Pulmonary microvascular dysfunction and pathological changes induced by blast injury in a rabbit model.

PubMed

Wu, Si Yu; Han, Geng Fen; Kang, Jian Yi; Zhang, Liang Chao; Wang, Ai Min; Wang, Jian Min

2016-09-01

Vascular leakage has been proven to play a critical role in the incidence and development of explosive pulmonary barotrauma. Quantitatively investigated in the present study was the severity of vascular leakage in a gradient blast injury series, as well as ultrastructural evidence relating to pulmonary vascular leakage. One hundred adult male New Zealand white rabbits were randomly divided into 5 groups according to distance from the detonator (10 cm, 15 cm, 20 cm, 30 cm, and sham control). Value of pulmonary vascular leakage was monitored by a radioactive 125I-albumin labeling method. Pathological changes caused by the blast wave were examined under light and electron microscopes. Transcapillary escape rate of 125I-albumin and residual radioactivity in both lungs increased significantly at the distances of 10 cm, 15 cm, and 20 cm, suggesting increased severity of vascular leakage in these groups. Ultrastructural observation showed swelling of pulmonary capillary endothelial cells and widened gap between endothelial cells in the 10-cm and 15-cm groups. Primary blast wave can result in pulmonary capillary blood leakage. Blast wave can cause swelling of pulmonary capillary endothelial cells and widened gap between endothelial cells, which may be responsible for pulmonary vascular leakage.

Ultrastructural brain abnormalities and associated behavioral changes in mice after low-intensity blast exposure.

PubMed

Song, Hailong; Konan, Landry M; Cui, Jiankun; Johnson, Catherine E; Langenderfer, Martin; Grant, DeAna; Ndam, Tina; Simonyi, Agnes; White, Tommi; Demirci, Utkan; Mott, David R; Schwer, Doug; Hubler, Graham K; Cernak, Ibolja; DePalma, Ralph G; Gu, Zezong

2018-07-16

Explosive blast-induced mild traumatic brain injury (mTBI), a "signature wound" of recent military conflicts, commonly affects service members. While past blast injury studies have provided insights into TBI with moderate- to high-intensity explosions, the impact of primary low-intensity blast (LIB)-mediated pathobiology on neurological deficits requires further investigation. Our prior considerations of blast physics predicted ultrastructural injuries at nanoscale levels. Here, we provide quantitative data using a primary LIB injury murine model exposed to open field detonation of 350 g of high-energy explosive C4. We quantified ultrastructural and behavioral changes up to 30 days post blast injury (DPI). The use of an open-field experimental blast generated a primary blast wave with a peak overpressure of 6.76 PSI (46.6 kPa) at a 3-m distance from the center of the explosion, a positive phase duration of approximate 3.0 milliseconds (ms), a maximal impulse of 8.7 PSI × ms and a sharp rising time of 9 × 10 -3  ms, with no apparent impact/acceleration in exposed animals. Neuropathologically, myelinated axonal damage was observed in blast-exposed groups at 7 DPI. Using transmission electron microscopy, we observed and quantified myelin sheath defects and mitochondrial abnormalities at 7 and 30 DPI. Inverse correlations between blast intensities and neurobehavioral outcomes including motor activities, anxiety levels, nesting behavior, spatial learning and memory occurred. These observations uncover unique ultrastructural brain abnormalities and associated behavioral changes due to primary blast injury and provide key insights into its pathogenesis and potential treatment. Copyright © 2018 Elsevier B.V. All rights reserved.

Low-cost blast wave generator for studies of hearing loss and brain injury: blast wave effects in closed spaces.

PubMed

Newman, Andrew J; Hayes, Sarah H; Rao, Abhiram S; Allman, Brian L; Manohar, Senthilvelan; Ding, Dalian; Stolzberg, Daniel; Lobarinas, Edward; Mollendorf, Joseph C; Salvi, Richard

2015-03-15

Military personnel and civilians living in areas of armed conflict have increased risk of exposure to blast overpressures that can cause significant hearing loss and/or brain injury. The equipment used to simulate comparable blast overpressures in animal models within laboratory settings is typically very large and prohibitively expensive. To overcome the fiscal and space limitations introduced by previously reported blast wave generators, we developed a compact, low-cost blast wave generator to investigate the effects of blast exposures on the auditory system and brain. The blast wave generator was constructed largely from off the shelf components, and reliably produced blasts with peak sound pressures of up to 198dB SPL (159.3kPa) that were qualitatively similar to those produced from muzzle blasts or explosions. Exposure of adult rats to 3 blasts of 188dB peak SPL (50.4kPa) resulted in significant loss of cochlear hair cells, reduced outer hair cell function and a decrease in neurogenesis in the hippocampus. Existing blast wave generators are typically large, expensive, and are not commercially available. The blast wave generator reported here provides a low-cost method of generating blast waves in a typical laboratory setting. This compact blast wave generator provides scientists with a low cost device for investigating the biological mechanisms involved in blast wave injury to the rodent cochlea and brain that may model many of the damaging effects sustained by military personnel and civilians exposed to intense blasts. Copyright © 2015 Elsevier B.V. All rights reserved.

Low-Cost Blast Wave Generator for Studies of Hearing Loss and Brain Injury: Blast Wave Effects in Closed Spaces

PubMed Central

Newman, Andrew J.; Hayes, Sarah H.; Rao, Abhiram S.; Allman, Brian L.; Manohar, Senthilvelan; Ding, Dalian; Stolzberg, Daniel; Lobarinas, Edward; Mollendorf, Joseph C.; Salvi, Richard

2015-01-01

Background Military personnel and civilians living in areas of armed conflict have increased risk of exposure to blast overpressures that can cause significant hearing loss and/or brain injury. The equipment used to simulate comparable blast overpressures in animal models within laboratory settings is typically very large and prohibitively expensive. New Method To overcome the fiscal and space limitations introduced by previously reported blast wave generators, we developed a compact, low-cost blast wave generator to investigate the effects of blast exposures on the auditory system and brain. Results The blast wave generator was constructed largely from off the shelf components, and reliably produced blasts with peak sound pressures of up to 198 dB SPL (159.3 kPa) that were qualitatively similar to those produced from muzzle blasts or explosions. Exposure of adult rats to 3 blasts of 188 dB peak SPL (50.4 kPa) resulted in significant loss of cochlear hair cells, reduced outer hair cell function and a decrease in neurogenesis in the hippocampus. Comparison to existing methods Existing blast wave generators are typically large, expensive, and are not commercially available. The blast wave generator reported here provides a low-cost method of generating blast waves in a typical laboratory setting. Conclusions This compact blast wave generator provides scientists with a low cost device for investigating the biological mechanisms involved in blast wave injury to the rodent cochlea and brain that may model many of the damaging effects sustained by military personnel and civilians exposed to intense blasts. PMID:25597910

Primary Blast-Induced Traumatic Brain Injury in Rats Leads to Increased Prion Protein in Plasma: A Potential Biomarker for Blast-Induced Traumatic Brain Injury

PubMed Central

Pham, Nam; Sawyer, Thomas W.; Wang, Yushan; Jazii, Ferdous Rastgar; Vair, Cory

2015-01-01

Abstract Traumatic brain injury (TBI) is deemed the “signature injury” of recent military conflicts in Afghanistan and Iraq, largely because of increased blast exposure. Injuries to the brain can often be misdiagnosed, leading to further complications in the future. Therefore, the use of protein biomarkers for the screening and diagnosis of TBI is urgently needed. In the present study, we have investigated the plasma levels of soluble cellular prion protein (PrPC) as a novel biomarker for the diagnosis of primary blast-induced TBI (bTBI). We hypothesize that the primary blast wave can disrupt the brain and dislodge extracellular localized PrPC, leading to a rise in concentration within the systemic circulation. Adult male Sprague–Dawley rats were exposed to single pulse shockwave overpressures of varying intensities (15-30 psi or 103.4–206.8 kPa] using an advanced blast simulator. Blood plasma was collected 24 h after insult, and PrPC concentration was determined with a modified commercial enzyme-linked immunosorbent assay (ELISA) specific for PrPC. We provide the first report that mean PrPC concentration in primary blast exposed rats (3.97 ng/mL±0.13 SE) is significantly increased compared with controls (2.46 ng/mL±0.14 SE; two tailed test p<0.0001). Furthermore, we report a mild positive rank correlation between PrPC concentration and increasing blast intensity (psi) reflecting a plateaued response at higher pressure magnitudes, which may have implications for all military service members exposed to blast events. In conclusion, it appears that plasma levels of PrPC may be a novel biomarker for the detection of primary bTBI. PMID:25058115

On the Propagation and Interaction of Spherical Blast Waves

NASA Technical Reports Server (NTRS)

Kandula, Max; Freeman, Robert

2007-01-01

The characteristics and the scaling laws of isolated spherical blast waves have been briefly reviewed. Both self-similar solutions and numerical solutions of isolated blast waves are discussed. Blast profiles in the near-field (strong shock region) and the far-field (weak shock region) are examined. Particular attention is directed at the blast overpressure and shock propagating speed. Consideration is also given to the interaction of spherical blast waves. Test data for the propagation and interaction of spherical blast waves emanating from explosives placed in the vicinity of a solid propellant stack are presented. These data are discussed with regard to the scaling laws concerning the decay of blast overpressure.

Brain Response to Primary Blast Wave Using Validated Finite Element Models of Human Head and Advanced Combat Helmet

PubMed Central

Zhang, Liying; Makwana, Rahul; Sharma, Sumit

2013-01-01

Blast-induced traumatic brain injury has emerged as a “signature injury” in combat casualty care. Present combat helmets are designed primarily to protect against ballistic and blunt impacts, but the current issue with helmets is protection concerning blasts. In order to delineate the blast wave attenuating capability of the Advanced Combat Helmet (ACH), a finite element (FE) study was undertaken to evaluate the head response against blast loadings with and without helmet using a partially validated FE model of the human head and ACH. Four levels of overpressures (0.27–0.66 MPa) from the Bowen’s lung iso-damage threshold curves were used to simulate blast insults. Effectiveness of the helmet with respect to head orientation was also investigated. The resulting biomechanical responses of the brain to blast threats were compared for human head with and without the helmet. For all Bowen’s cases, the peak intracranial pressures (ICP) in the head ranged from 0.68 to 1.8 MPa in the coup cortical region. ACH was found to mitigate ICP in the head by 10–35%. Helmeted head resulted in 30% lower average peak brain strains and product of strain and strain rate. Among three blast loading directions with ACH, highest reduction in peak ICP (44%) was due to backward blasts whereas the lowest reduction in peak ICP and brain strains was due to forward blast (27%). The biomechanical responses of a human head to primary blast insult exhibited directional sensitivity owing to the different geometry contours and coverage of the helmet construction and asymmetric anatomy of the head. Thus, direction-specific tolerances are needed in helmet design in order to offer omni-directional protection for the human head. The blasts of varying peak overpressures and durations that are believed to produce the same level of lung injury produce different levels of mechanical responses in the brain, and hence “iso-damage” curves for brain injury are likely different than the Bowen curves for lung injury. PMID:23935591

Blast lung injury.

PubMed

Sasser, Scott M; Sattin, Richard W; Hunt, Richard C; Krohmer, Jon

2006-01-01

Current trends in global terrorism mandate that emergency medical services, emergency medicine and other acute care clinicians have a basic understanding of the physics of explosions, the types of injuries that can result from an explosion, and current management for patients injured by explosions. High-order explosive detonations result in near instantaneous transformation of the explosive material into a highly pressurized gas, releasing energy at supersonic speeds. This results in the formation of a blast wave that travels out from the epicenter of the blast. Primary blast injuries are characterized by anatomical and physiological changes from the force generated by the blast wave impacting the body's surface, and affect primarily gas-containing structures (lungs, gastrointestinal tract, ears). "Blast lung" is a clinical diagnosis and is characterized as respiratory difficulty and hypoxia without obvious external injury to the chest. It may be complicated by pneumothoraces and air emboli and may be associated with multiple other injuries. Patients may present with a variety of symptoms, including dyspnea, chest pain, cough, and hemoptysis. Physical examination may reveal tachypnea, hypoxia, cyanosis, and decreased breath sounds. Chest radiography, computerized tomography, and arterial blood gases may assist with diagnosis and management; however, they should not delay diagnosis and emergency interventions in the patient exposed to a blast. High flow oxygen, airway management, tube thoracostomy in the setting of pneumothoraces, mechanical ventilation (when required) with permissive hypercapnia, and judicious fluid administration are essential components in the management of blast lung injury.

75 FR 4793 - Availability for Non-Exclusive, Exclusive, or Partially Exclusive Licensing of U.S. Provisional...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-29

... Partially Exclusive Licensing of U.S. Provisional Patent Application Concerning Blast Wave Sensor AGENCY... ``Blast Wave Sensor,'' filed January 4, 2010. The United States Government, as represented by the... wave sensors and their use to detect blast induced pressure changes, and, in particular, a blast wave...

Blast overpressure after tire explosion: a fatal case.

PubMed

Pomara, Cristoforo; D'Errico, Stefano; Riezzo, Irene; Perilli, Gabriela; Volpe, Umberto; Fineschi, Vittorio

2013-12-01

Fatal blast injuries are generally reported in literature as a consequence of the detonation of explosives in war settings. The pattern of lesion depends on the position of the victim in relation to the explosion, on whether the blast tracks through air or water, and whether it happens in the open air or within an enclosed space and the distance from the explosion. Tire explosion-related injuries are rarely reported in literature. This study presents a fatal case of blast overpressure due to the accidental explosion of a truck tire occurring in a tire repair shop. A multidisciplinary approach to the fatality involving forensic pathologists and engineers revealed that the accidental explosion, which caused a series of primary and tertiary blast wave injuries, was due to tire deterioration.

Development of a multimodal blast sensor for measurement of head impact and over-pressurization exposure.

PubMed

Chu, Jeffrey J; Beckwith, Jonathan G; Leonard, Daniel S; Paye, Corey M; Greenwald, Richard M

2012-01-01

It is estimated that 10-20% of United States soldiers returning from Operation Iraqi Freedom (OIF) and Operation Enduring Freedom (OEF) have suffered at least one instance of blast-induced traumatic brain injury (bTBI) with many reporting persistent symptomology and long-term effects. This variation in blast response may be related to the complexity of blast waves and the many mechanisms of injury, including over-pressurization due to the shock wave and potential for blunt impacts to the head from shrapnel or from other indirect impacts (e.g., building, ground, and vehicle). To help differentiate the effects of primary, secondary, and tertiary effects of blast, a custom sensor was developed to simultaneously measure over-pressurization and blunt impact. Moreover, a custom, complementary filter was designed to differentiate the measurements of blunt (low-frequency bandwidth) from over-pressurization (high-frequency bandwidth). The custom sensor was evaluated in the laboratory using a shock tube to simulate shock waves and a drop fixture to simulate head impacts. Both bare sensors and sensor embedded within an ACH helmet coupon were compared to laboratory reference transducers under multiple loading conditions (n = 5) and trials at each condition (n = 3). For all comparative measures, peak magnitude, peak impulse, and cross-correlation measures, R (2) values, were greater than 0.900 indicating excellent agreement of peak measurements and time-series comparisons with laboratory measures.

Model for small arms fire muzzle blast wave propagation in air

NASA Astrophysics Data System (ADS)

Aguilar, Juan R.; Desai, Sachi V.

2011-11-01

Accurate modeling of small firearms muzzle blast wave propagation in the far field is critical to predict sound pressure levels, impulse durations and rise times, as functions of propagation distance. Such a task being relevant to a number of military applications including the determination of human response to blast noise, gunfire detection and localization, and gun suppressor design. Herein, a time domain model to predict small arms fire muzzle blast wave propagation is introduced. The model implements a Friedlander wave with finite rise time which diverges spherically from the gun muzzle. Additionally, the effects in blast wave form of thermoviscous and molecular relaxational processes, which are associated with atmospheric absorption of sound were also incorporated in the model. Atmospheric absorption of blast waves is implemented using a time domain recursive formula obtained from numerical integration of corresponding differential equations using a Crank-Nicholson finite difference scheme. Theoretical predictions from our model were compared to previously recorded real world data of muzzle blast wave signatures obtained by shooting a set different sniper weapons of varying calibers. Recordings containing gunfire acoustical signatures were taken at distances between 100 and 600 meters from the gun muzzle. Results shows that predicted blast wave slope and exponential decay agrees well with measured data. Analysis also reveals the persistency of an oscillatory phenomenon after blast overpressure in the recorded wave forms.

Blast-wave density measurements

NASA Astrophysics Data System (ADS)

Ritzel, D. V.

Applications of a densitometer to obtain time-resolved data on the total density in blast-wave flows are described. A beta-source (promethium-147) is separated by a gap from a scintillator and a photomultiplier tube (PMT). Attenuation of the radiation beam by the passing blast wave is due to the total density in the gap volume during the wave passage. Signal conditioning and filtering methods permit the system to output linearized data. Results are provided from use of the system to monitor blast waves emitted by detonation of a 10.7 m diameter fiberglass sphere containing 609 tons of ammonium nitrate/fuel oil at a 50.6 m height. Blast wave density data are provided for peak overpressure levels of 245, 172 and 70 kPa and distances of 183, 201 and 314 m from ground zero. Data resolution was of high enough quality to encourage efforts to discriminate dust and gasdynamic phenomena within passing blast waves.

Reduction of optically observed artillery blast wave trajectories using low dimensionality models

NASA Astrophysics Data System (ADS)

Steward, Bryan J.; Gross, Kevin C.; Perram, Glen P.

2011-05-01

Muzzle blast trajectories from firings of a 152 mm caliber gun howitzer were obtained with high-speed optical imagers and used to assess the fidelity with which low dimensionality models can be used for data reduction. Characteristic flow regions were defined for the blast waves. The near-field region was estimated to extend to 0.98 - 1.25 meters from the muzzle and the far-field region was estimated to begin at 2.61 - 3.31 meters. Blast wave geometries and radial trajectories were collected in the near through far-fields with visible imagers operating at 1,600 Hz. Beyond the near-field the blast waves exhibited a near-spherical geometry in which the major axis of the blast lay along the axis of the gun barrel and measured within 95% of the minor axis. Several blast wave propagation models were applied to the mid and far-field data to determine their ability to reduce the blast wave trajectories to fewer parameters while retaining the ability to distinguish amongst three munitions configurations. A total of 147 firings were observed and used to assess within-configuration variability relative to separation between configurations. Results show that all models perform well, and drag and point blast model parameters additionally provide insight into phenomenology of the blast.

Two-dimensional explosion experiments examining the interaction between a blast wave and a sand hill

NASA Astrophysics Data System (ADS)

Sugiyama, Y.; Izumo, M.; Ando, H.; Matsuo, A.

2018-05-01

Two-dimensional explosion experiments were conducted to discuss the interaction between a blast wave and sand and show the mitigation effect of the sand on the blast wave. The explosive used was a detonating cord 1.0 m in length, which was initiated in a sand hill shaped like a triangular prism and whose cross section was an isosceles triangle with base angles of 30°. Sand-hill heights of 30 and 60 mm were used as parameters to discuss the effect of sand mass upon blast-wave strength. The interaction of the blast wave with the sand/air interface causes multiple peaks in the blast wave, which are induced by successive transmissions at the interface. The increase in the sand mass further mitigates the blast parameters of peak overpressure and positive impulse. The results of this experiment can be utilized to validate the numerical method of solving the problem of interaction between a compressible fluid and a particle layer.

Two-dimensional explosion experiments examining the interaction between a blast wave and a sand hill

NASA Astrophysics Data System (ADS)

Sugiyama, Y.; Izumo, M.; Ando, H.; Matsuo, A.

2018-02-01

Two-dimensional explosion experiments were conducted to discuss the interaction between a blast wave and sand and show the mitigation effect of the sand on the blast wave. The explosive used was a detonating cord 1.0 m in length, which was initiated in a sand hill shaped like a triangular prism and whose cross section was an isosceles triangle with base angles of 30°. Sand-hill heights of 30 and 60 mm were used as parameters to discuss the effect of sand mass upon blast-wave strength. The interaction of the blast wave with the sand/air interface causes multiple peaks in the blast wave, which are induced by successive transmissions at the interface. The increase in the sand mass further mitigates the blast parameters of peak overpressure and positive impulse. The results of this experiment can be utilized to validate the numerical method of solving the problem of interaction between a compressible fluid and a particle layer.

Numerical modeling and characterization of blast waves for application in blast-induced mild traumatic brain injury research

NASA Astrophysics Data System (ADS)

Phillips, Michael G.

Human exposure to blast waves, including blast-induced traumatic brain injury, is a developing field in medical research. Experiments with explosives have many disadvantages including safety, cost, and required area for trials. Shock tubes provide an alternative method to produce free field blast wave profiles. A compressed nitrogen shock tube experiment instrumented with static and reflective pressure taps is modeled using a numerical simulation. The geometry of the numerical model is simplified and blast wave characteristics are derived based upon static and pressure profiles. The pressure profiles are analyzed along the shock tube centerline and radially away from the tube axis. The blast wave parameters found from the pressure profiles provide guidelines for spatial location of a specimen. The location could be based on multiple parameters and provides a distribution of anticipated pressure profiles experience by the specimen.

Translational Research for Blast-Induced Traumatic Brain Injury: Injury Mechanism to Development of Medical Instruments

NASA Astrophysics Data System (ADS)

Nakagawa, A.; Ohtani, K.; Arafune, T.; Washio, T.; Iwasaki, M.; Endo, T.; Ogawa, Y.; Kumabe, T.; Takayama, K.; Tominaga, T.

1. Investigation of shock wave-induced phenomenon: blast-induced traumatic brain injury Blast wave (BW) is generated by explosion and is comprised of lead shock wave (SE) followed by subsequent supersonic flow.

The quinary pattern of blast injury.

PubMed

Kluger, Yoram; Nimrod, Adi; Biderman, Philippe; Mayo, Ami; Sorkin, Patric

2007-01-01

Bombing is the primary weapon of global terrorism, and it results in a complicated, multidimensional injury pattern. It induces bodily injuries through the well-documented primary, secondary, tertiary, and quaternary mechanisms of blast. Their effects dictate special medical concern and timely implementation of diagnostic and management strategies. Our objective is to report on clinical observations of patients admitted to the Tel Aviv Medical Center following a terrorist bombing. The explosion injured 27 patients, and three died. Four survivors who had been in close proximity to the explosion, as indicated by their eardrum perforation and additional blast injuries, were exposed to the blast wave. They exhibited a unique and immediate hyperinflammatory state, two upon admission to the intensive care unit and two during surgery. This hyperinflammatory state manifested as hyperpyrexia, sweating, low central venous pressure, and positive fluid balance. This state did not correlate with the complexity of injuries sustained by any of the 67 patients admitted to the intensive care unit after previous bombings. The patients' hyperinflammatory behavior, unrelated to their injury complexity and severity of trauma, indicates a new injury pattern in explosions, termed the "quinary blast injury pattern." Unconventional materials used in the manufacture of the explosive can partly explain the observed early hyperinflammatory state. Medical personnel caring for blast victims should be aware of this new type of bombing injury.

Instability of Taylor-Sedov blast waves propagating through a uniform gas

NASA Astrophysics Data System (ADS)

Grun, J.; Stamper, J.; Manka, C.; Resnick, J.; Burris, R.; Crawford, J.; Ripin, B. H.

1991-05-01

An instability in Taylor-Sedov blast waves was measured as the waves propagated through a uniform gas with a low adiabatic index. The first measurements of the instability are given and compared to theoretical predictions. The classical Taylor-Sedov blast waves resulted from the expansion of ablation plasma into an ambient gas from laser-irradiated foils, and photographs were taken using the dark-field imaging method. Visible emission from the blasts were recorded with a four-frame microchannel-plate intensifier camera. Blast waves formed in nitrogen gas are shown to be stable and smooth, whereas the waves propagating through xenon gas are found to be unstable and wrinkled. A power law is fitted to the experimental data, and the adiabatic indices are theorized to cause the different responses in the two gases. The results generally agree with theoretical predictions in spite of some minor discrepancies, and an explanation of the instability mechanism is developed. When the adiabatic index is sufficiently low, the Taylor-Sedov blast waves in a uniform gas will be unstable, and the perturbed amplitudes will grow as a power of time.

Dynamic response analysis of surrounding rock under the continuous blasting seismic wave

NASA Astrophysics Data System (ADS)

Gao, P. F.; Zong, Q.; Xu, Y.; Fu, J.

2017-10-01

The blasting vibration that is caused by blasting excavation will generate a certain degree of negative effect on the stability of surrounding rock in underground engineering. A dynamic response analysis of surrounding rock under the continuous blasting seismic wave is carried out to optimize blasting parameters and guide underground engineering construction. Based on the theory of wavelet analysis, the reconstructed signals of each layer of different frequency bands are obtained by db8 wavelet decomposition. The difference of dynamic response of the continuous blasting seismic wave at a certain point caused by different blasting sources is discussed. The signal in the frequency band of natural frequency of the surrounding rock shows a certain degree of amplification effect deduced from the dynamic response characteristics of the surrounding rock under the influence of continuous blasting seismic wave. Continuous blasting operations in a fixed space will lead to the change of internal structure of the surrounding rock. It may result in the decline of natural frequency of the whole surrounding rock and it is also harmful for the stability of the surrounding rock.

Characterising the acceleration phase of blast wave formation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fox, T. E., E-mail: tef503@york.ac.uk; Pasley, J.; Central Laser Facility, STFC Rutherford Appleton Laboratory, Harwell Oxford, Didcot OX11 0QX

2014-10-15

Intensely heated, localised regions in uniform fluids will rapidly expand and generate an outwardly propagating blast wave. The Sedov-Taylor self-similar solution for such blast waves has long been studied and applied to a variety of scenarios. A characteristic time for their formation has also long been identified using dimensional analysis, which by its very nature, can offer several interpretations. We propose that, rather than simply being a characteristic time, it may be interpreted as the definitive time taken for a blast wave resulting from an intense explosion in a uniform media to contain its maximum kinetic energy. A scaling relationmore » for this measure of the acceleration phase, preceding the establishment of the blast wave, is presented and confirmed using a 1D planar hydrodynamic model.« less

Suspended liquid particle disturbance on laser-induced blast wave and low density distribution

NASA Astrophysics Data System (ADS)

Ukai, Takahiro; Zare-Behtash, Hossein; Kontis, Konstantinos

2017-12-01

The impurity effect of suspended liquid particles on the laser-induced gas breakdown was experimentally investigated in quiescent gas. The focus of this study is the investigation of the influence of the impurities on the shock wave structure as well as the low density distribution. A 532 nm Nd:YAG laser beam with an 188 mJ/pulse was focused on the chamber filled with suspended liquid particles 0.9 ± 0.63 μm in diameter. Several shock waves are generated by multiple gas breakdowns along the beam path in the breakdown with particles. Four types of shock wave structures can be observed: (1) the dual blast waves with a similar shock radius, (2) the dual blast waves with a large shock radius at the lower breakdown, (3) the dual blast waves with a large shock radius at the upper breakdown, and (4) the triple blast waves. The independent blast waves interact with each other and enhance the shock strength behind the shock front in the lateral direction. The triple blast waves lead to the strongest shock wave in all cases. The shock wave front that propagates toward the opposite laser focal spot impinges on one another, and thereafter a transmitted shock wave (TSW) appears. The TSW interacts with the low density core called a kernel; the kernel then longitudinally expands quickly due to a Richtmyer-Meshkov-like instability. The laser-particle interaction causes an increase in the kernel volume which is approximately five times as large as that in the gas breakdown without particles. In addition, the laser-particle interaction can improve the laser energy efficiency.

Experimental investigation of blast mitigation and particle-blast interaction during the explosive dispersal of particles and liquids

NASA Astrophysics Data System (ADS)

Pontalier, Q.; Loiseau, J.; Goroshin, S.; Frost, D. L.

2018-04-01

The attenuation of a blast wave from a high-explosive charge surrounded by a layer of inert material is investigated experimentally in a spherical geometry for a wide range of materials. The blast wave pressure is inferred from extracting the blast wave velocity with high-speed video as well as direct measurements with pressure transducers. The mitigant consists of either a packed bed of particles, a particle bed saturated with water, or a homogeneous liquid. The reduction in peak blast wave overpressure is primarily dependent on the mitigant to explosive mass ratio, M/C, with the mitigant material properties playing a secondary role. Relative peak pressure mitigation reduces with distance and for low values of M/C (< 10) can return to unmitigated pressure levels in the mid-to-far field. Solid particles are more effective at mitigating the blast overpressure than liquids, particularly in the near field and at low values of M/C, suggesting that the energy dissipation during compaction, deformation, and fracture of the powders plays an important role. The difference in scaled arrival time of the blast and material fronts increases with M/C and scaled distance, with solid particles giving the largest separation between the blast wave and cloud of particles. Surrounding a high-explosive charge with a layer of particles reduces the positive-phase blast impulse, whereas a liquid layer has no influence on the impulse in the far field. Taking the total impulse due to the blast wave and material impact into account implies that the damage to a nearby structure may actually be augmented for a range of distances. These results should be taken into consideration in the design of explosive mitigant systems.

Experimental investigation of blast mitigation and particle-blast interaction during the explosive dispersal of particles and liquids

NASA Astrophysics Data System (ADS)

Pontalier, Q.; Loiseau, J.; Goroshin, S.; Frost, D. L.

2018-05-01

The attenuation of a blast wave from a high-explosive charge surrounded by a layer of inert material is investigated experimentally in a spherical geometry for a wide range of materials. The blast wave pressure is inferred from extracting the blast wave velocity with high-speed video as well as direct measurements with pressure transducers. The mitigant consists of either a packed bed of particles, a particle bed saturated with water, or a homogeneous liquid. The reduction in peak blast wave overpressure is primarily dependent on the mitigant to explosive mass ratio, M/ C, with the mitigant material properties playing a secondary role. Relative peak pressure mitigation reduces with distance and for low values of M/ C (< 10) can return to unmitigated pressure levels in the mid-to-far field. Solid particles are more effective at mitigating the blast overpressure than liquids, particularly in the near field and at low values of M/ C, suggesting that the energy dissipation during compaction, deformation, and fracture of the powders plays an important role. The difference in scaled arrival time of the blast and material fronts increases with M/ C and scaled distance, with solid particles giving the largest separation between the blast wave and cloud of particles. Surrounding a high-explosive charge with a layer of particles reduces the positive-phase blast impulse, whereas a liquid layer has no influence on the impulse in the far field. Taking the total impulse due to the blast wave and material impact into account implies that the damage to a nearby structure may actually be augmented for a range of distances. These results should be taken into consideration in the design of explosive mitigant systems.

Note: A table-top blast driven shock tube

NASA Astrophysics Data System (ADS)

Courtney, Michael W.; Courtney, Amy C.

2010-12-01

The prevalence of blast-induced traumatic brain injury in conflicts in Iraq and Afghanistan has motivated laboratory scale experiments on biomedical effects of blast waves and studies of blast wave transmission properties of various materials in hopes of improving armor design to mitigate these injuries. This paper describes the design and performance of a table-top shock tube that is more convenient and widely accessible than traditional compression driven and blast driven shock tubes. The design is simple: it is an explosive driven shock tube employing a rifle primer that explodes when impacted by the firing pin. The firearm barrel acts as the shock tube, and the shock wave emerges from the muzzle. The small size of this shock tube can facilitate localized application of a blast wave to a subject, tissue, or material under test.

Note: A table-top blast driven shock tube.

PubMed

Courtney, Michael W; Courtney, Amy C

2010-12-01

The prevalence of blast-induced traumatic brain injury in conflicts in Iraq and Afghanistan has motivated laboratory scale experiments on biomedical effects of blast waves and studies of blast wave transmission properties of various materials in hopes of improving armor design to mitigate these injuries. This paper describes the design and performance of a table-top shock tube that is more convenient and widely accessible than traditional compression driven and blast driven shock tubes. The design is simple: it is an explosive driven shock tube employing a rifle primer that explodes when impacted by the firing pin. The firearm barrel acts as the shock tube, and the shock wave emerges from the muzzle. The small size of this shock tube can facilitate localized application of a blast wave to a subject, tissue, or material under test.

Quick reproduction of blast-wave flow-field properties of nuclear, TNT, and ANFO explosions

NASA Astrophysics Data System (ADS)

Groth, C. P. T.

1986-04-01

In many instances, extensive blast-wave flow-field properties are required in gasdynamics research studies of blast-wave loading and structure response, and in evaluating the effects of explosions on their environment. This report provides a very useful computer code, which can be used in conjunction with the DNA Nuclear Blast Standard subroutines and code, to quickly reconstruct complete and fairly accurate blast-wave data for almost any free-air (spherical) and surface-burst (hemispherical) nuclear, trinitrotoluene (TNT), or ammonium nitrate-fuel oil (ANFO) explosion. This code is capable of computing all of the main flow properties as functions of radius and time, as well as providing additional information regarding air viscosity, reflected shock-wave properties, and the initial decay of the flow properties just behind the shock front. Both spatial and temporal distributions of the major blast-wave flow properties are also made readily available. Finally, provisions are also included in the code to provide additional information regarding the peak or shock-front flow properties over a range of radii, for a specific explosion of interest.

On the Interaction and Coalescence if Spherical Blast Waves

NASA Technical Reports Server (NTRS)

Kandula, Max; Freeman, Robert J.

2005-01-01

The scaling and similarity laws concerning the propagation of isolated spherical blast waves are briefly reviewed. Both point source explosions and high pressure gas explosions are considered. Test data on blast overpressure from the interaction and coalescence of spherical blast waves emanating from explosives in the form of shaped charges of different strength placed in the vicinity of a solid propellant stack are presented. These data are discussed with regard to the scaling laws concerning the decay of blast overpressure. The results point out the possibility of detecting source explosions from far-field pressure measurements.

Dynamics and Afterglow Light Curves of Gamma-Ray Burst Blast Waves Encountering a Density Bump or Void

NASA Astrophysics Data System (ADS)

Uhm, Z. Lucas; Zhang, Bing

2014-07-01

We investigate the dynamics and afterglow light curves of gamma-ray burst blast waves that encounter various density structures (such as bumps, voids, or steps) in the surrounding ambient medium. We present and explain the characteristic response features that each type of density structure in the medium leaves on the forward shock (FS) and reverse shock (RS) dynamics for blast waves with either a long-lived or short-lived RS. We show that when the ambient medium density drops, the blast waves exhibit in some cases a period of an actual acceleration (even during their deceleration stage) due to adiabatic cooling of blast waves. Comparing numerical examples that have different shapes of bumps or voids, we propose a number of consistency tests that must be satisfied by correct modeling of blast waves. Our model results successfully pass these tests. Employing a Lagrangian description of blast waves, we perform a sophisticated calculation of afterglow emission. We show that as a response to density structures in the ambient medium, the RS light curves produce more significant variations than the FS light curves. Some observed features (such as rebrightenings, dips, or slow wiggles) can be more easily explained within the RS model. We also discuss the origin of these different features imprinted on the FS and RS light curves.

Close-in Blast Waves from Spherical Charges*

NASA Astrophysics Data System (ADS)

Howard, William; Kuhl, Allen

2011-06-01

We study the close-in blast waves created by the detonation of spherical high explosives (HE) charges, via numerical simulations with our Arbitrary-Lagrange-Eulerian (ALE3D) code. We used a finely-resolved, fixed Eulerian 2-D mesh (200 μm per cell) to capture the detonation of the charge, the blast wave propagation in air, and the reflection of the blast wave from an ideal surface. The thermodynamic properties of the detonation products and air were specified by the Cheetah code. A programmed-burn model was used to detonate the charge at a rate based on measured detonation velocities. The results were analyzed to evaluate the: (i) free air pressure-range curves: Δps (R) , (ii) free air impulse curves, (iii) reflected pressure-range curves, and (iv) reflected impulse-range curves. A variety of explosives were studied. Conclusions are: (i) close-in (R < 10 cm /g 1 / 3) , each explosive had its own (unique) blast wave (e.g., Δps (R , HE) ~ a /Rn , where n is different for each explosive); (ii) these close-in blast waves do not scale with the ``Heat of Detonation'' of the explosive (because close-in, there is not enough time to fully couple the chemical energy to the air via piston work); (iii) instead they are related to the detonation conditions inside the charge. Scaling laws will be proposed for such close-in blast waves.

Integrated Experimental Platforms to Study Blast Injuries: a Bottom-Up Approach

NASA Astrophysics Data System (ADS)

Bo, Chiara

2013-06-01

Developing a cellular and molecular understanding of the nature of traumatic and post-traumatic effects of blast events on live biological samples is critical for improving clinical outcomes.1 To investigate the consequences of pressure waves upon cellular structures and the underlying physiological and biochemical changes, we are using an integrated approach to study the material and biological properties of cells, tissues and organs when subjected to extreme conditions. In particular we have developed a confined Split Hopkinson Pressure Bar (SHPB) system, which allows us to subject cells in suspension or in a monolayer to compression waves of the order of few MPa and duration of hundreds of microseconds.2 The chamber design also enables recovery of the biological samples for cellular and molecular analysis. Specifically, cell survivability, viability, proliferation and morphological changes are investigated post compression for different cell populations. The SHPB platform, coupled with Quasi-Static experiments, is also used to determine stress-strain curves of soft biological tissues under compression at low, medium and high strain rates. Samples are also examined using histological techniques to study macro- and microscopical changes induced by compression waves. Finally, a shock tube has been developed to replicate primary blast damage on organs (i.e. mice lungs) and cell monolayers by generating single or multiple air blast of the order of kPa and few milliseconds duration. This platform allows us to visualize post-traumatic morphological changes at the cellular level as a function of the stimulus pressure and duration as well as biomarker signatures of blast injuries. Adapting and integrating a variety of approaches with different experimental platforms allows us to sample a vast pressure-time space in terms of biological and structural damage that mimic blast injuries and also to determine which physical parameters (peak pressure, stimulus duration, impulse) are contributing to the injury process. Moreover, understanding biological damage following blast events is crucial to developing novel clinical approaches to detect and treat traumatic injury pathologies. This work is supported by he Atomic Weapons Establishment, UK and The Royal British Legion Centre for Blast Injury Studies at Imperial College London, UK

Numerical investigation of particle-blast interaction during explosive dispersal of liquids and granular materials

NASA Astrophysics Data System (ADS)

Pontalier, Q.; Lhoumeau, M.; Milne, A. M.; Longbottom, A. W.; Frost, D. L.

2018-05-01

Experiments show that when a high-explosive charge with embedded particles or a charge surrounded by a layer of liquid or granular material is detonated, the flow generated is perturbed by the motion of the particles and the blast wave profile differs from that of an ideal Friedlander form. Initially, the blast wave overpressure is reduced due to the energy dissipation resulting from compaction, fragmentation, and heating of the particle bed, and acceleration of the material. However, as the blast wave propagates, particle-flow interactions collectively serve to reduce the rate of decay of the peak blast wave overpressure. Computations carried out with a multiphase hydrocode reproduce the general trends observed experimentally and highlight the transition between the particle acceleration/deceleration phases, which is not accessible experimentally, since the particles are obscured by the detonation products. The dependence of the particle-blast interaction and the blast mitigation effectiveness on the mitigant to explosive mass ratio, the particle size, and the initial solid volume fraction is investigated systematically. The reduction in peak blast overpressure is, as in experiments, primarily dependent on the mass ratio of material to explosive, with the particle size, density, and initial porosity of the particle bed playing secondary roles. In the near field, the blast overpressure decreases sharply with distance as the particles are accelerated by the flow. When the particles decelerate due to drag, energy is returned to the flow and the peak blast overpressure recovers and reaches values similar to that of a bare explosive charge for low mass ratios. Time-distance trajectory plots of the particle and blast wave motion with the pressure field superimposed, illustrate the weak pressure waves generated by the motion of the particle layer which travel upstream and perturb the blast wave motion. Computation of the particle and gas momentum flux in the multiphase flow generated during explosive particle dispersal indicates that the particle momentum flux is the dominant term in the near field. Both the gas and particle loading must be taken into account when determining the damage to nearby structures following the detonation of a high-explosive charge surrounded by a material layer.

Numerical investigation of particle-blast interaction during explosive dispersal of liquids and granular materials

NASA Astrophysics Data System (ADS)

Pontalier, Q.; Lhoumeau, M.; Milne, A. M.; Longbottom, A. W.; Frost, D. L.

2018-04-01

Experiments show that when a high-explosive charge with embedded particles or a charge surrounded by a layer of liquid or granular material is detonated, the flow generated is perturbed by the motion of the particles and the blast wave profile differs from that of an ideal Friedlander form. Initially, the blast wave overpressure is reduced due to the energy dissipation resulting from compaction, fragmentation, and heating of the particle bed, and acceleration of the material. However, as the blast wave propagates, particle-flow interactions collectively serve to reduce the rate of decay of the peak blast wave overpressure. Computations carried out with a multiphase hydrocode reproduce the general trends observed experimentally and highlight the transition between the particle acceleration/deceleration phases, which is not accessible experimentally, since the particles are obscured by the detonation products. The dependence of the particle-blast interaction and the blast mitigation effectiveness on the mitigant to explosive mass ratio, the particle size, and the initial solid volume fraction is investigated systematically. The reduction in peak blast overpressure is, as in experiments, primarily dependent on the mass ratio of material to explosive, with the particle size, density, and initial porosity of the particle bed playing secondary roles. In the near field, the blast overpressure decreases sharply with distance as the particles are accelerated by the flow. When the particles decelerate due to drag, energy is returned to the flow and the peak blast overpressure recovers and reaches values similar to that of a bare explosive charge for low mass ratios. Time-distance trajectory plots of the particle and blast wave motion with the pressure field superimposed, illustrate the weak pressure waves generated by the motion of the particle layer which travel upstream and perturb the blast wave motion. Computation of the particle and gas momentum flux in the multiphase flow generated during explosive particle dispersal indicates that the particle momentum flux is the dominant term in the near field. Both the gas and particle loading must be taken into account when determining the damage to nearby structures following the detonation of a high-explosive charge surrounded by a material layer.

Two-material optimization of plate armour for blast mitigation using hybrid cellular automata

NASA Astrophysics Data System (ADS)

Goetz, J.; Tan, H.; Renaud, J.; Tovar, A.

2012-08-01

With the increased use of improvised explosive devices in regions at war, the threat to military and civilian life has risen. Cabin penetration and gross acceleration are the primary threats in an explosive event. Cabin penetration crushes occupants, damaging the lower body. Acceleration causes death at high magnitudes. This investigation develops a process of designing armour that simultaneously mitigates cabin penetration and acceleration. The hybrid cellular automaton (HCA) method of topology optimization has proven efficient and robust in problems involving large, plastic deformations such as crash impact. Here HCA is extended to the design of armour under blast loading. The ability to distribute two metallic phases, as opposed to one material and void, is also added. The blast wave energy transforms on impact into internal energy (IE) inside the solid medium. Maximum attenuation occurs with maximized IE. The resulting structures show HCA's potential for designing blast mitigating armour structures.

Planar blast scaling with condensed-phase explosives in a shock tube

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jackson, Scott L

2011-01-25

Blast waves are strong shock waves that result from large power density deposition into a fluid. The rapid energy release of high-explosive (HE) detonation provides sufficiently high power density for blast wave generation. Often it is desirable to quantify the energy released by such an event and to determine that energy relative to other reference explosives to derive an explosive-equivalence value. In this study, we use condensed-phase explosives to drive a blast wave in a shock tube. The explosive material and quantity were varied to produce blast waves of differing strengths. Pressure transducers at varying lengths measured the post-shock pressure,more » shock-wave arrival time and sidewall impulse associated with each test. Blast-scaling concepts in a one-dimensional geometry were then used to both determine the energy release associated with each test and to verify the scaling of the shock position versus time, overpressure versus distance, and impulse. Most blast scaling measurements to-date have been performed in a three-dimensional geometry such as a blast arena. Testing in a three-dimensional geometry can be challenging, however, as spherical shock-wave symmetry is required for good measurements. Additionally, the spherical wave strength decays rapidly with distance and it can be necessary to utilize larger (several kg) quantities of explosive to prevent significant decay from occurring before an idealized blast wave has formed. Such a mode of testing can be expensive, require large quantities of explosive, and be limited by both atmospheric conditions (such as rain) and by noise complaints from the population density near the test arena. Testing is possible in more compact geometries, however. Non-planar blast waves can be formed into a quasi-planar shape by confining the shock diffraction with the walls of a shock tube. Regardless of the initial form, the wave shape will begin to approximate a planar front after successive wave reflections from the tube walls. Such a technique has previously been used to obtain blast scaling measurements in the planar geometry with gaseous explosives and the condensed-phase explosive nitroguanidine. Recently, there has been much interest in the blast characterization of various non-ideal high explosive (NIHE) materials. With non-ideals, the detonation reaction zone is significantly larger (up to several cm for ANFO) than more ideal explosives. Wave curvature, induced by charge-geometry, can significantly affect the energy release associated with NIHEs. To measure maximum NIHE energy release accurately, it is desirable to minimize any such curvature and, if possible, to overdrive the detonation shock to ensure completion of chemical reactions ahead of the sonic locus associated with the reaction zone. This is achieved in the current study through use of a powerful booster HE and a charge geometry consisting of short cylindrical lengths of NIHE initiated along the charge centerline.« less

Controlled Low-Pressure Blast-Wave Exposure Causes Distinct Behavioral and Morphological Responses Modelling Mild Traumatic Brain Injury, Post-Traumatic Stress Disorder, and Comorbid Mild Traumatic Brain Injury-Post-Traumatic Stress Disorder.

PubMed

Zuckerman, Amitai; Ram, Omri; Ifergane, Gal; Matar, Michael A; Sagi, Ram; Ostfeld, Ishay; Hoffman, Jay R; Kaplan, Zeev; Sadot, Oren; Cohen, Hagit

2017-01-01

The intense focus in the clinical literature on the mental and neurocognitive sequelae of explosive blast-wave exposure, especially when comorbid with post-traumatic stress-related disorders (PTSD) is justified, and warrants the design of translationally valid animal studies to provide valid complementary basic data. We employed a controlled experimental blast-wave paradigm in which unanesthetized animals were exposed to visual, auditory, olfactory, and tactile effects of an explosive blast-wave produced by exploding a thin copper wire. By combining cognitive-behavioral paradigms and ex vivo brain MRI to assess mild traumatic brain injury (mTBI) phenotype with a validated behavioral model for PTSD, complemented by morphological assessments, this study sought to examine our ability to evaluate the biobehavioral effects of low-intensity blast overpressure on rats, in a translationally valid manner. There were no significant differences between blast- and sham-exposed rats on motor coordination and strength, or sensory function. Whereas most male rats exposed to the blast-wave displayed normal behavioral and cognitive responses, 23.6% of the rats displayed a significant retardation of spatial learning acquisition, fulfilling criteria for mTBI-like responses. In addition, 5.4% of the blast-exposed animals displayed an extreme response in the behavioral tasks used to define PTSD-like criteria, whereas 10.9% of the rats developed both long-lasting and progressively worsening behavioral and cognitive "symptoms," suggesting comorbid PTSD-mTBI-like behavioral and cognitive response patterns. Neither group displayed changes on MRI. Exposure to experimental blast-wave elicited distinct behavioral and morphological responses modelling mTBI-like, PTSD-like, and comorbid mTBI-PTSD-like responses. This experimental animal model can be a useful tool for elucidating neurobiological mechanisms underlying the effects of blast-wave-induced mTBI and PTSD and comorbid mTBI-PTSD.

Role of helmet in the mechanics of shock wave propagation under blast loading conditions.

PubMed

Ganpule, S; Gu, L; Alai, A; Chandra, N

2012-01-01

The effectiveness of helmets in extenuating the primary shock waves generated by the explosions of improvised explosive devices is not clearly understood. In this work, the role of helmet on the overpressurisation and impulse experienced by the head were examined. The shock wave-head interactions were studied under three different cases: (i) unprotected head, (ii) head with helmet but with varying head-helmet gaps and (iii) head covered with helmet and tightly fitting foam pads. The intensification effect was discussed by examining the shock wave flow pattern and verified with experiments. A helmet with a better protection against shock wave is suggested.

Chronic Traumatic Encephalopathy in Blast-Exposed Military Veterans and a Blast Neurotrauma Mouse Model

PubMed Central

Goldstein, Lee E.; Fisher, Andrew M.; Tagge, Chad A.; Zhang, Xiao-Lei; Velisek, Libor; Sullivan, John A.; Upreti, Chirag; Kracht, Jonathan M.; Ericsson, Maria; Wojnarowicz, Mark W.; Goletiani, Cezar J.; Maglakelidze, Giorgi M.; Casey, Noel; Moncaster, Juliet A.; Minaeva, Olga; Moir, Robert D.; Nowinski, Christopher J.; Stern, Robert A.; Cantu, Robert C.; Geiling, James; Blusztajn, Jan K.; Wolozin, Benjamin L.; Ikezu, Tsuneya; Stein, Thor D.; Budson, Andrew E.; Kowall, Neil W.; Chargin, David; Sharon, Andre; Saman, Sudad; Hall, Garth F.; Moss, William C.; Cleveland, Robin O.; Tanzi, Rudolph E.; Stanton, Patric K.; McKee, Ann C.

2013-01-01

Blast exposure is associated with traumatic brain injury (TBI), neuropsychiatric symptoms, and long-term cognitive disability. We examined a case series of postmortem brains from U.S. military veterans exposed to blast and/or concussive injury. We found evidence of chronic traumatic encephalopathy (CTE), a tau protein–linked neurodegenerative disease, that was similar to the CTE neuropathology observed in young amateur American football players and a professional wrestler with histories of concussive injuries. We developed a blast neurotrauma mouse model that recapitulated CTE-linked neuropathology in wild-type C57BL/6 mice 2 weeks after exposure to a single blast. Blast-exposed mice demonstrated phosphorylated tauopathy, myelinated axonopathy, microvasculopathy, chronic neuroinflammation, and neurodegeneration in the absence of macroscopic tissue damage or hemorrhage. Blast exposure induced persistent hippocampal-dependent learning and memory deficits that persisted for at least 1 month and correlated with impaired axonal conduction and defective activity-dependent long-term potentiation of synaptic transmission. Intracerebral pressure recordings demonstrated that shock waves traversed the mouse brain with minimal change and without thoracic contributions. Kinematic analysis revealed blast-induced head oscillation at accelerations sufficient to cause brain injury. Head immobilization during blast exposure prevented blast-induced learning and memory deficits. The contribution of blast wind to injurious head acceleration may be a primary injury mechanism leading to blast-related TBI and CTE. These results identify common pathogenic determinants leading to CTE in blast-exposed military veterans and head-injured athletes and additionally provide mechanistic evidence linking blast exposure to persistent impairments in neurophysiological function, learning, and memory. PMID:22593173

Chronic traumatic encephalopathy in blast-exposed military veterans and a blast neurotrauma mouse model.

PubMed

Goldstein, Lee E; Fisher, Andrew M; Tagge, Chad A; Zhang, Xiao-Lei; Velisek, Libor; Sullivan, John A; Upreti, Chirag; Kracht, Jonathan M; Ericsson, Maria; Wojnarowicz, Mark W; Goletiani, Cezar J; Maglakelidze, Giorgi M; Casey, Noel; Moncaster, Juliet A; Minaeva, Olga; Moir, Robert D; Nowinski, Christopher J; Stern, Robert A; Cantu, Robert C; Geiling, James; Blusztajn, Jan K; Wolozin, Benjamin L; Ikezu, Tsuneya; Stein, Thor D; Budson, Andrew E; Kowall, Neil W; Chargin, David; Sharon, Andre; Saman, Sudad; Hall, Garth F; Moss, William C; Cleveland, Robin O; Tanzi, Rudolph E; Stanton, Patric K; McKee, Ann C

2012-05-16

Blast exposure is associated with traumatic brain injury (TBI), neuropsychiatric symptoms, and long-term cognitive disability. We examined a case series of postmortem brains from U.S. military veterans exposed to blast and/or concussive injury. We found evidence of chronic traumatic encephalopathy (CTE), a tau protein-linked neurodegenerative disease, that was similar to the CTE neuropathology observed in young amateur American football players and a professional wrestler with histories of concussive injuries. We developed a blast neurotrauma mouse model that recapitulated CTE-linked neuropathology in wild-type C57BL/6 mice 2 weeks after exposure to a single blast. Blast-exposed mice demonstrated phosphorylated tauopathy, myelinated axonopathy, microvasculopathy, chronic neuroinflammation, and neurodegeneration in the absence of macroscopic tissue damage or hemorrhage. Blast exposure induced persistent hippocampal-dependent learning and memory deficits that persisted for at least 1 month and correlated with impaired axonal conduction and defective activity-dependent long-term potentiation of synaptic transmission. Intracerebral pressure recordings demonstrated that shock waves traversed the mouse brain with minimal change and without thoracic contributions. Kinematic analysis revealed blast-induced head oscillation at accelerations sufficient to cause brain injury. Head immobilization during blast exposure prevented blast-induced learning and memory deficits. The contribution of blast wind to injurious head acceleration may be a primary injury mechanism leading to blast-related TBI and CTE. These results identify common pathogenic determinants leading to CTE in blast-exposed military veterans and head-injured athletes and additionally provide mechanistic evidence linking blast exposure to persistent impairments in neurophysiological function, learning, and memory.

Blast shock wave mitigation using the hydraulic energy redirection and release technology.

PubMed

Chen, Yun; Huang, Wei; Constantini, Shlomi

2012-01-01

A hydraulic energy redirection and release technology has been developed for mitigating the effects of blast shock waves on protected objects. The technology employs a liquid-filled plastic tubing as a blast overpressure transformer to transfer kinetic energy of blast shock waves into hydraulic energy in the plastic tubings. The hydraulic energy is redirected through the plastic tubings to the openings at the lower ends, and then is quickly released with the liquid flowing out through the openings. The samples of the specifically designed body armor in which the liquid-filled plastic tubings were installed vertically as the outer layer of the body armor were tested. The blast test results demonstrated that blast overpressure behind the body armor samples was remarkably reduced by 97% in 0.2 msec after the liquid flowed out of its appropriate volume through the openings. The results also suggested that a volumetric liquid surge might be created when kinetic energy of blast shock wave was transferred into hydraulic energy to cause a rapid physical movement or displacement of the liquid. The volumetric liquid surge has a strong destructive power, and can cause a noncontact, remote injury in humans (such as blast-induced traumatic brain injury and post-traumatic stress disorder) if it is created in cardiovascular system. The hydraulic energy redirection and release technology can successfully mitigate blast shock waves from the outer surface of the body armor. It should be further explored as an innovative approach to effectively protect against blast threats to civilian and military personnel.

Blast Shock Wave Mitigation Using the Hydraulic Energy Redirection and Release Technology

PubMed Central

Chen, Yun; Huang, Wei; Constantini, Shlomi

2012-01-01

A hydraulic energy redirection and release technology has been developed for mitigating the effects of blast shock waves on protected objects. The technology employs a liquid-filled plastic tubing as a blast overpressure transformer to transfer kinetic energy of blast shock waves into hydraulic energy in the plastic tubings. The hydraulic energy is redirected through the plastic tubings to the openings at the lower ends, and then is quickly released with the liquid flowing out through the openings. The samples of the specifically designed body armor in which the liquid-filled plastic tubings were installed vertically as the outer layer of the body armor were tested. The blast test results demonstrated that blast overpressure behind the body armor samples was remarkably reduced by 97% in 0.2 msec after the liquid flowed out of its appropriate volume through the openings. The results also suggested that a volumetric liquid surge might be created when kinetic energy of blast shock wave was transferred into hydraulic energy to cause a rapid physical movement or displacement of the liquid. The volumetric liquid surge has a strong destructive power, and can cause a noncontact, remote injury in humans (such as blast-induced traumatic brain injury and post-traumatic stress disorder) if it is created in cardiovascular system. The hydraulic energy redirection and release technology can successfully mitigate blast shock waves from the outer surface of the body armor. It should be further explored as an innovative approach to effectively protect against blast threats to civilian and military personnel. PMID:22745740

Challenging Some Contemporary Views of Coronal Mass Ejections. I. The Case for Blast Waves

NASA Astrophysics Data System (ADS)

Howard, T. A.; Pizzo, V. J.

2016-06-01

Since the closure of the “solar flare myth” debate in the mid-1990s, a specific narrative of the nature of coronal mass ejections (CMEs) has been widely accepted by the solar physics community. This narrative describes structured magnetic flux ropes at the CME core that drive the surrounding field plasma away from the Sun. This narrative replaced the “traditional” view that CMEs were blast waves driven by solar flares. While the flux rope CME narrative is supported by a vast quantity of measurements made over five decades, it does not adequately describe every observation of what have been termed CME-related phenomena. In this paper we present evidence that some large-scale coronal eruptions, particularly those associated with EIT waves, exhibit characteristics that are more consistent with a blast wave originating from a localized region (such as a flare site) rather than a large-scale structure driven by an intrinsic flux rope. We present detailed examples of CMEs that are suspected blast waves and flux ropes, and show that of our small sample of 22 EIT-wave-related CMEs, 91% involve a blast wave as at least part of the eruption, and 50% are probably blast waves exclusively. We conclude with a description of possible signatures to look for in determining the difference between the two types of CMEs and with a discussion on modeling efforts to explore this possibility.

Neurodegeneration and Vision Loss after Mild Blunt Trauma in the C57Bl/6 and DBA/2J Mouse

PubMed Central

Bricker-Anthony, Courtney; Rex, Tonia S.

2015-01-01

Damage to the eye from blast exposure can occur as a result of the overpressure air-wave (primary injury), flying debris (secondary injury), blunt force trauma (tertiary injury), and/or chemical/thermal burns (quaternary injury). In this study, we investigated damage in the contralateral eye after a blast directed at the ipsilateral eye in the C57Bl/6J and DBA/2J mouse. Assessments of ocular health (gross pathology, electroretinogram recordings, optokinetic tracking, optical coherence tomography and histology) were performed at 3, 7, 14 and 28 days post-trauma. Olfactory epithelium and optic nerves were also examined. Anterior pathologies were more common in the DBA/2J than in the C57Bl/6 and could be prevented with non-medicated viscous eye drops. Visual acuity decreased over time in both strains, but was more rapid and severe in the DBA/2J. Retinal cell death was present in approximately 10% of the retina at 7 and 28 days post-blast in both strains. Approximately 60% of the cell death occurred in photoreceptors. Increased oxidative stress and microglial reactivity was detected in both strains, beginning at 3 days post-injury. However, there was no sign of injury to the olfactory epithelium or optic nerve in either strain. Although our model directs an overpressure air-wave at the left eye in a restrained and otherwise protected mouse, retinal damage was detected in the contralateral eye. The lack of damage to the olfactory epithelium and optic nerve, as well as the different timing of cell death as compared to the blast-exposed eye, suggests that the injuries were due to physical contact between the contralateral eye and the housing chamber of the blast device and not propagation of the blast wave through the head. Thus we describe a model of mild blunt eye trauma. PMID:26148200

Study of blasting seismic effects of underground powerhouse of pumped storage project in granite condition

NASA Astrophysics Data System (ADS)

Wan, Sheng; Li, Hui

2018-03-01

Though the test of blasting vibration, the blasting seismic wave propagation laws in southern granite pumped storage power project are studied. Attenuation coefficient of seismic wave and factors coefficient are acquired by the method of least squares regression analysis according to Sadaovsky empirical formula, and the empirical formula of seismic wave is obtained. This paper mainly discusses on the test of blasting vibration and the procedure of calculation. Our practice might as well serve as a reference for similar projects to come.

Low Level Primary Blast Injury in Rodent Brain

PubMed Central

Pun, Pamela B. L.; Kan, Enci Mary; Salim, Agus; Li, Zhaohui; Ng, Kian Chye; Moochhala, Shabbir M.; Ling, Eng-Ang; Tan, Mui Hong; Lu, Jia

2011-01-01

The incidence of blast attacks and resulting traumatic brain injuries has been on the rise in recent years. Primary blast is one of the mechanisms in which the blast wave can cause injury to the brain. The aim of this study was to investigate the effects of a single sub-lethal blast over pressure (BOP) exposure of either 48.9 kPa (7.1 psi) or 77.3 kPa (11.3 psi) to rodents in an open-field setting. Brain tissue from these rats was harvested for microarray and histopathological analyses. Gross histopathology of the brains showed that cortical neurons were “darkened” and shrunken with narrowed vasculature in the cerebral cortex day 1 after blast with signs of recovery at day 4 and day 7 after blast. TUNEL-positive cells were predominant in the white matter of the brain at day 1 after blast and double-labeling of brain tissue showed that these DNA-damaged cells were both oligodendrocytes and astrocytes but were mainly not apoptotic due to the low caspase-3 immunopositivity. There was also an increase in amyloid precursor protein immunoreactive cells in the white matter which suggests acute axonal damage. In contrast, Iba-1 staining for macrophages or microglia was not different from control post-blast. Blast exposure altered the expression of over 5786 genes in the brain which occurred mostly at day 1 and day 4 post-blast. These genes were narrowed down to 10 overlapping genes after time-course evaluation and functional analyses. These genes pointed toward signs of repair at day 4 and day 7 post-blast. Our findings suggest that the BOP levels in the study resulted in mild cellular injury to the brain as evidenced by acute neuronal, cerebrovascular, and white matter perturbations that showed signs of resolution. It is unclear whether these perturbations exist at a milder level or normalize completely and will need more investigation. Specific changes in gene expression may be further evaluated to understand the mechanism of blast-induced neurotrauma. PMID:21541261

Micro-blast waves using detonation transmission tubing

NASA Astrophysics Data System (ADS)

Samuelraj, I. Obed; Jagadeesh, G.; Kontis, K.

2013-07-01

Micro-blast waves emerging from the open end of a detonation transmission tube were experimentally visualized in this study. A commercially available detonation transmission tube was used (Nonel tube, M/s Dyno Nobel, Sweden), which is a small diameter tube coated with a thin layer of explosive mixture (HMX + traces of Al) on its inner side. The typical explosive loading for this tube is of the order of 18 mg/m of tube length. The blast wave was visualized using a high speed digital camera (frame rate 1 MHz) to acquire time-resolved schlieren images of the resulting flow field. The visualization studies were complemented by computational fluid dynamic simulations. An analysis of the schlieren images showed that although the blast wave appears to be spherical, it propagates faster along the tube axis than along a direction perpendicular to the tube axis. Additionally, CFD analysis revealed the presence of a barrel shock and Mach disc, showing structures that are typical of an underexpanded jet. A theory in use for centered large-scale explosions of intermediate strength (10 < Δ {p}/{p}_0 ≲ 0.02) gave good agreement with the blast trajectory along the tube axis. The energy of these micro-blast waves was found to be 1.25 ± 0.94 J and the average TNT equivalent was found to be 0.3. The repeatability in generating these micro-blast waves using the Nonel tube was very good (± 2 %) and this opens up the possibility of using this device for studying some of the phenomena associated with muzzle blasts in the near future.

Dynamics and afterglow light curves of gamma-ray burst blast waves encountering a density bump or void

DOE Office of Scientific and Technical Information (OSTI.GOV)

Uhm, Z. Lucas; Zhang, Bing, E-mail: uhm@pku.edu.cn, E-mail: zhang@physics.unlv.edu

2014-07-01

We investigate the dynamics and afterglow light curves of gamma-ray burst blast waves that encounter various density structures (such as bumps, voids, or steps) in the surrounding ambient medium. We present and explain the characteristic response features that each type of density structure in the medium leaves on the forward shock (FS) and reverse shock (RS) dynamics for blast waves with either a long-lived or short-lived RS. We show that when the ambient medium density drops, the blast waves exhibit in some cases a period of an actual acceleration (even during their deceleration stage) due to adiabatic cooling of blastmore » waves. Comparing numerical examples that have different shapes of bumps or voids, we propose a number of consistency tests that must be satisfied by correct modeling of blast waves. Our model results successfully pass these tests. Employing a Lagrangian description of blast waves, we perform a sophisticated calculation of afterglow emission. We show that as a response to density structures in the ambient medium, the RS light curves produce more significant variations than the FS light curves. Some observed features (such as rebrightenings, dips, or slow wiggles) can be more easily explained within the RS model. We also discuss the origin of these different features imprinted on the FS and RS light curves.« less

POLYCYCLIC AROMATIC HYDROCARBON PROCESSING IN THE BLAST WAVE OF THE SUPERNOVA REMNANT N132D

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tappe, A.; Rho, J.; Boersma, C.

2012-08-01

We present Spitzer Infrared Spectrograph 14-36 {mu}m mapping observations of the supernova remnant N132D in the Large Magellanic Cloud. This study focuses on the processing of polycyclic aromatic hydrocarbons (PAHs) that we previously identified in the southern blast wave. The mid-infrared spectra show strong continuum emission from shock-heated dust and a unique, nearly featureless plateau in the 15-20 {mu}m region, which we attribute to PAH molecules. The typical PAH emission bands observed in the surrounding interstellar medium ahead of the blast wave disappear, which indicates shock processing of PAH molecules. The PAH plateau appears most strongly at the outer edgemore » of the blast wave and coincides with diffuse X-ray emission that precedes the brightest X-ray and optical filaments. This suggests that PAH molecules in the surrounding medium are swept up and processed in the hot gas of the blast wave shock, where they survive the harsh conditions long enough to be detected. We also observe a broad emission feature at 20 {mu}m appearing with the PAH plateau. We speculate that this feature is either due to FeO dust grains or connected to the processing of PAHs in the supernova blast wave shock.« less

Tailoring the Blast Exposure Conditions in the Shock Tube for Generating Pure, Primary Shock Waves: The End Plate Facilitates Elimination of Secondary Loading of the Specimen

PubMed Central

Misistia, Anthony; Kahali, Sudeepto; Sundaramurthy, Aravind; Chandra, Namas

2016-01-01

The end plate mounted at the mouth of the shock tube is a versatile and effective implement to control and mitigate the end effects. We have performed a series of measurements of incident shock wave velocities and overpressures followed by quantification of impulse values (integral of pressure in time domain) for four different end plate configurations (0.625, 2, 4 inches, and an open end). Shock wave characteristics were monitored by high response rate pressure sensors allocated in six positions along the length of 6 meters long 229 mm square cross section shock tube. Tests were performed at three shock wave intensities, which was controlled by varying the Mylar membrane thickness (0.02, 0.04 and 0.06 inch). The end reflector plate installed at the exit of the shock tube allows precise control over the intensity of reflected waves penetrating into the shock tube. At the optimized distance of the tube to end plate gap the secondary waves were entirely eliminated from the test section, which was confirmed by pressure sensor at T4 location. This is pronounced finding for implementation of pure primary blast wave animal model. These data also suggest only deep in the shock tube experimental conditions allow exposure to a single shock wave free of artifacts. Our results provide detailed insight into spatiotemporal dynamics of shock waves with Friedlander waveform generated using helium as a driver gas and propagating in the air inside medium sized tube. Diffusion of driver gas (helium) inside the shock tube was responsible for velocity increase of reflected shock waves. Numerical simulations combined with experimental data suggest the shock wave attenuation mechanism is simply the expansion of the internal pressure. In the absence of any other postulated shock wave decay mechanisms, which were not implemented in the model the agreement between theory and experimental data is excellent. PMID:27603017

Tailoring the Blast Exposure Conditions in the Shock Tube for Generating Pure, Primary Shock Waves: The End Plate Facilitates Elimination of Secondary Loading of the Specimen.

PubMed

Kuriakose, Matthew; Skotak, Maciej; Misistia, Anthony; Kahali, Sudeepto; Sundaramurthy, Aravind; Chandra, Namas

2016-01-01

The end plate mounted at the mouth of the shock tube is a versatile and effective implement to control and mitigate the end effects. We have performed a series of measurements of incident shock wave velocities and overpressures followed by quantification of impulse values (integral of pressure in time domain) for four different end plate configurations (0.625, 2, 4 inches, and an open end). Shock wave characteristics were monitored by high response rate pressure sensors allocated in six positions along the length of 6 meters long 229 mm square cross section shock tube. Tests were performed at three shock wave intensities, which was controlled by varying the Mylar membrane thickness (0.02, 0.04 and 0.06 inch). The end reflector plate installed at the exit of the shock tube allows precise control over the intensity of reflected waves penetrating into the shock tube. At the optimized distance of the tube to end plate gap the secondary waves were entirely eliminated from the test section, which was confirmed by pressure sensor at T4 location. This is pronounced finding for implementation of pure primary blast wave animal model. These data also suggest only deep in the shock tube experimental conditions allow exposure to a single shock wave free of artifacts. Our results provide detailed insight into spatiotemporal dynamics of shock waves with Friedlander waveform generated using helium as a driver gas and propagating in the air inside medium sized tube. Diffusion of driver gas (helium) inside the shock tube was responsible for velocity increase of reflected shock waves. Numerical simulations combined with experimental data suggest the shock wave attenuation mechanism is simply the expansion of the internal pressure. In the absence of any other postulated shock wave decay mechanisms, which were not implemented in the model the agreement between theory and experimental data is excellent.

CHALLENGING SOME CONTEMPORARY VIEWS OF CORONAL MASS EJECTIONS. I. THE CASE FOR BLAST WAVES

DOE Office of Scientific and Technical Information (OSTI.GOV)

Howard, T. A.; Pizzo, V. J., E-mail: howard@boulder.swri.edu

Since the closure of the “solar flare myth” debate in the mid-1990s, a specific narrative of the nature of coronal mass ejections (CMEs) has been widely accepted by the solar physics community. This narrative describes structured magnetic flux ropes at the CME core that drive the surrounding field plasma away from the Sun. This narrative replaced the “traditional” view that CMEs were blast waves driven by solar flares. While the flux rope CME narrative is supported by a vast quantity of measurements made over five decades, it does not adequately describe every observation of what have been termed CME-related phenomena.more » In this paper we present evidence that some large-scale coronal eruptions, particularly those associated with EIT waves, exhibit characteristics that are more consistent with a blast wave originating from a localized region (such as a flare site) rather than a large-scale structure driven by an intrinsic flux rope. We present detailed examples of CMEs that are suspected blast waves and flux ropes, and show that of our small sample of 22 EIT-wave-related CMEs, 91% involve a blast wave as at least part of the eruption, and 50% are probably blast waves exclusively. We conclude with a description of possible signatures to look for in determining the difference between the two types of CMEs and with a discussion on modeling efforts to explore this possibility.« less

Experimental Animal Models for Studies on the Mechanisms of Blast-Induced Neurotrauma

PubMed Central

Risling, Mårten; Davidsson, Johan

2012-01-01

A blast injury is a complex type of physical trauma resulting from the detonation of explosive compounds and has become an important issue due to the use of improvised explosive devices (IED) in current military conflicts. Blast-induced neurotrauma (BINT) is a major concern in contemporary military medicine and includes a variety of injuries that range from mild to lethal. Extreme forces and their complex propagation characterize BINT. Modern body protection and the development of armored military vehicles can be assumed to have changed the outcome of BINT. Primary blast injuries are caused by overpressure waves whereas secondary, tertiary, and quaternary blast injuries can have more varied origins such as the impact of fragments, abnormal movements, or heat. The characteristics of the blast wave can be assumed to be significantly different in open field detonations compared to explosions in a confined space, such an armored vehicle. Important parameters include peak pressure, duration, and shape of the pulse. Reflections from walls and armor can make the prediction of effects in individual cases very complex. Epidemiological data do not contain information of the comparative importance of the different blast mechanisms. It is therefore important to generate data in carefully designed animal models. Such models can be selective reproductions of a primary blast, penetrating injuries from fragments, acceleration movements, or combinations of such mechanisms. It is of crucial importance that the physical parameters of the employed models are well characterized so that the experiments can be reproduced in different laboratory settings. Ideally, pressure recordings should be calibrated by using the same equipment in several laboratories. With carefully designed models and thoroughly evaluated animal data it should be possible to achieve a translation of data between animal and clinical data. Imaging and computer simulation represent a possible link between experiments and studies of human cases. However, in order for mathematical simulations to be completely useful, the predictions will most likely have to be validated by detailed data from animal experiments. Some aspects of BINT can conceivably be studied in vitro. However, factors such as systemic response, brain edema, inflammation, vasospasm, or changes in synaptic transmission and behavior must be evaluated in experimental animals. Against this background, it is necessary that such animal experiments are carefully developed imitations of actual components in the blast injury. This paper describes and discusses examples of different designs of experimental models relevant to BINT. PMID:22485104

Viscoelastic Materials Study for the Mitigation of Blast-Related Brain Injury

NASA Astrophysics Data System (ADS)

Bartyczak, Susan; Mock, Willis, Jr.

2011-06-01

Recent preliminary research into the causes of blast-related brain injury indicates that exposure to blast pressures, such as from IED detonation or multiple firings of a weapon, causes damage to brain tissue resulting in Traumatic Brain Injury (TBI) and Post Traumatic Stress Disorder (PTSD). Current combat helmets are not sufficient to protect the warfighter from this danger and the effects are debilitating, costly, and long-lasting. Commercially available viscoelastic materials, designed to dampen vibration caused by shock waves, might be useful as helmet liners to dampen blast waves. The objective of this research is to develop an experimental technique to test these commercially available materials when subject to blast waves and evaluate their blast mitigating behavior. A 40-mm-bore gas gun is being used as a shock tube to generate blast waves (ranging from 1 to 500 psi) in a test fixture at the gun muzzle. A fast opening valve is used to release nitrogen gas from the breech to impact instrumented targets. The targets consist of aluminum/ viscoelastic polymer/ aluminum materials. Blast attenuation is determined through the measurement of pressure and accelerometer data in front of and behind the target. The experimental technique, calibration and checkout procedures, and results will be presented.

Dynamic Modelling of Fault Slip Induced by Stress Waves due to Stope Production Blasts

NASA Astrophysics Data System (ADS)

Sainoki, Atsushi; Mitri, Hani S.

2016-01-01

Seismic events can take place due to the interaction of stress waves induced by stope production blasts with faults located in close proximity to stopes. The occurrence of such seismic events needs to be controlled to ensure the safety of the mine operators and the underground mine workings. This paper presents the results of a dynamic numerical modelling study of fault slip induced by stress waves resulting from stope production blasts. First, the calibration of a numerical model having a single blast hole is performed using a charge weight scaling law to determine blast pressure and damping coefficient of the rockmass. Subsequently, a numerical model of a typical Canadian metal mine encompassing a fault parallel to a tabular ore deposit is constructed, and the simulation of stope extraction sequence is carried out with static analyses until the fault exhibits slip burst conditions. At that point, the dynamic analysis begins by applying the calibrated blast pressure to the stope wall in the form of velocities generated by the blast holes. It is shown from the results obtained from the dynamic analysis that the stress waves reflected on the fault create a drop of normal stresses acting on the fault, which produces a reduction in shear stresses while resulting in fault slip. The influence of blast sequences on the behaviour of the fault is also examined assuming several types of blast sequences. Comparison of the blast sequence simulation results indicates that performing simultaneous blasts symmetrically induces the same level of seismic events as separate blasts, although seismic energy is more rapidly released when blasts are performed symmetrically. On the other hand when nine blast holes are blasted simultaneously, a large seismic event is induced, compared to the other two blasts. It is concluded that the separate blasts might be employed under the adopted geological conditions. The developed methodology and procedure to arrive at an ideal blast sequence can be applied to other mines where faults are found in the vicinity of stopes.

Dynamics and stability of relativistic gamma-ray-bursts blast waves

NASA Astrophysics Data System (ADS)

Meliani, Z.; Keppens, R.

2010-09-01

Aims: In gamma-ray-bursts (GRBs), ultra-relativistic blast waves are ejected into the circumburst medium. We analyse in unprecedented detail the deceleration of a self-similar Blandford-McKee blast wave from a Lorentz factor 25 to the nonrelativistic Sedov phase. Our goal is to determine the stability properties of its frontal shock. Methods: We carried out a grid-adaptive relativistic 2D hydro-simulation at extreme resolving power, following the GRB jet during the entire afterglow phase. We investigate the effect of the finite initial jet opening angle on the deceleration of the blast wave, and identify the growth of various instabilities throughout the coasting shock front. Results: We find that during the relativistic phase, the blast wave is subject to pressure-ram pressure instabilities that ripple and fragment the frontal shock. These instabilities manifest themselves in the ultra-relativistic phase alone, remain in full agreement with causality arguments, and decay slowly to finally disappear in the near-Newtonian phase as the shell Lorentz factor drops below 3. From then on, the compression rate decreases to levels predicted to be stable by a linear analysis of the Sedov phase. Our simulations confirm previous findings that the shell also spreads laterally because a rarefaction wave slowly propagates to the jet axis, inducing a clear shell deformation from its initial spherical shape. The blast front becomes meridionally stratified, with decreasing speed from axis to jet edge. In the wings of the jetted flow, Kelvin-Helmholtz instabilities occur, which are of negligible importance from the energetic viewpoint. Conclusions: Relativistic blast waves are subject to hydrodynamical instabilities that can significantly affect their deceleration properties. Future work will quantify their effect on the afterglow light curves.

Oxy-acetylene driven laboratory scale shock tubes for studying blast wave effects

NASA Astrophysics Data System (ADS)

Courtney, Amy C.; Andrusiv, Lubov P.; Courtney, Michael W.

2012-04-01

This paper describes the development and characterization of modular, oxy-acetylene driven laboratory scale shock tubes. Such tools are needed to produce realistic blast waves in a laboratory setting. The pressure-time profiles measured at 1 MHz using high-speed piezoelectric pressure sensors have relevant durations and show a true shock front and exponential decay characteristic of free-field blast waves. Descriptions are included for shock tube diameters of 27-79 mm. A range of peak pressures from 204 kPa to 1187 kPa (with 0.5-5.6% standard error of the mean) were produced by selection of the driver section diameter and distance from the shock tube opening. The peak pressures varied predictably with distance from the shock tube opening while maintaining both a true blast wave profile and relevant pulse duration for distances up to about one diameter from the shock tube opening. This shock tube design provides a more realistic blast profile than current compression-driven shock tubes, and it does not have a large jet effect. In addition, operation does not require specialized personnel or facilities like most blast-driven shock tubes, which reduces operating costs and effort and permits greater throughput and accessibility. It is expected to be useful in assessing the response of various sensors to shock wave loading; assessing the reflection, transmission, and absorption properties of candidate armor materials; assessing material properties at high rates of loading; assessing the response of biological materials to shock wave exposure; and providing a means to validate numerical models of the interaction of shock waves with structures. All of these activities have been difficult to pursue in a laboratory setting due in part to lack of appropriate means to produce a realistic blast loading profile.

In silico investigation of intracranial blast mitigation with relevance to military traumatic brain injury.

PubMed

Nyein, Michelle K; Jason, Amanda M; Yu, Li; Pita, Claudio M; Joannopoulos, John D; Moore, David F; Radovitzky, Raul A

2010-11-30

Blast-induced traumatic brain injury is the most prevalent military injury in Iraq and Afghanistan, yet little is known about the mechanical effects of blasts on the human head, and still less is known about how personal protective equipment affects the brain's response to blasts. In this study we investigated the effect of the Advanced Combat Helmet (ACH) and a conceptual face shield on the propagation of stress waves within the brain tissue following blast events. We used a sophisticated computational framework for simulating coupled fluid-solid dynamic interactions and a three-dimensional biofidelic finite element model of the human head and intracranial contents combined with a detailed model of the ACH and a conceptual face shield. Simulations were conducted in which the unhelmeted head, head with helmet, and head with helmet and face shield were exposed to a frontal blast wave with incident overpressure of 10 atm. Direct transmission of stress waves into the intracranial cavity was observed in the unprotected head and head with helmet simulations. Compared to the unhelmeted head, the head with helmet experienced slight mitigation of intracranial stresses. This suggests that the existing ACH does not significantly contribute to mitigating blast effects, but does not worsen them either. By contrast, the helmet and face shield combination impeded direct transmission of stress waves to the face, resulting in a delay in the transmission of stresses to the intracranial cavity and lower intracranial stresses. This suggests a possible strategy for mitigating blast waves often associated with military concussion.

In silico investigation of intracranial blast mitigation with relevance to military traumatic brain injury

PubMed Central

Nyein, Michelle K.; Jason, Amanda M.; Yu, Li; Pita, Claudio M.; Joannopoulos, John D.; Moore, David F.; Radovitzky, Raul A.

2010-01-01

Blast-induced traumatic brain injury is the most prevalent military injury in Iraq and Afghanistan, yet little is known about the mechanical effects of blasts on the human head, and still less is known about how personal protective equipment affects the brain’s response to blasts. In this study we investigated the effect of the Advanced Combat Helmet (ACH) and a conceptual face shield on the propagation of stress waves within the brain tissue following blast events. We used a sophisticated computational framework for simulating coupled fluid–solid dynamic interactions and a three-dimensional biofidelic finite element model of the human head and intracranial contents combined with a detailed model of the ACH and a conceptual face shield. Simulations were conducted in which the unhelmeted head, head with helmet, and head with helmet and face shield were exposed to a frontal blast wave with incident overpressure of 10 atm. Direct transmission of stress waves into the intracranial cavity was observed in the unprotected head and head with helmet simulations. Compared to the unhelmeted head, the head with helmet experienced slight mitigation of intracranial stresses. This suggests that the existing ACH does not significantly contribute to mitigating blast effects, but does not worsen them either. By contrast, the helmet and face shield combination impeded direct transmission of stress waves to the face, resulting in a delay in the transmission of stresses to the intracranial cavity and lower intracranial stresses. This suggests a possible strategy for mitigating blast waves often associated with military concussion. PMID:21098257

Mild neurotrauma indicates a range-specific pressure response to low level shock wave exposure.

PubMed

Vandevord, Pamela J; Bolander, Richard; Sajja, Venkata Siva Sai Sujith; Hay, Kathryn; Bir, Cynthia A

2012-01-01

Identifying the level of overpressure required to create physiological deficits is vital to advance prevention, diagnostic, and treatment strategies for individuals exposed to blasts. In this study, a rodent model of primary blast neurotrauma was employed to determine the pressure at which acute neurological alterations occurred. Rats were exposed to a single low intensity shock wave at a pressure of 0, 97, 117, or 153 kPa. Following exposure, rats were assessed for acute cognitive alterations using the Morris water maze and motor dysfunction using the horizontal ladder test. Subsequently, histological analyses of three brain regions (primary motor cortex, the hippocampal dentate gyrus region, and the posteromedial cortical amygdala) were conducted. Histological parameters included measuring the levels of glial fibrillary acidic protein (GFAP) to identify astrocyte activation, cleaved caspase-3 for early apoptosis identification and Fluoro-Jade B (FJB) which labels degenerating neurons within the brain tissue. The results demonstrated that an exposure to a single 117 kPa shock wave revealed a significant change in overall neurological deficits when compared to controls and the other pressures. The animals showed significant alterations in water maze parameters and a histological increase in the number of GFAP, caspase-3, and FJB-positive cells. It is suggested that when exposed to a low level shock wave, there may be a biomechanical response elicited by a specific pressure range which can cause low level neurological deficits within the rat. These data indicate that neurotrauma induced from a shock wave may lead to cognitive deficits in short-term learning and memory of rats. Additional histological evidence supports significant and diffuse glial activation and cellular damage. Further investigation into the biomechanical aspects of shock wave exposure is required to elucidate this pressure range-specific phenomenon.

A Finite Difference Numerical Model for the Propagation of Finite Amplitude Acoustical Blast Waves Outdoors Over Hard and Porous Surfaces

DTIC Science & Technology

1991-09-01

Difference Numerical Model for the Propagation of Finite Amplitude Acoustical Blast Waves Outdoors Over Hard and Porous Surfaces by Victor W. Sparrow...The nonlinear acoustic propagation effects require a numerical solution in the time domain. To model a porous ground surface, which in the frequency...incident on the hard and porous surfaces were produced. The model predicted that near grazing finite amplitude acoustic blast waves decay with distance

Large blast and thermal simulator advanced concept driver design by computational fluid dynamics. Final report, 1987-1989

DOE Office of Scientific and Technical Information (OSTI.GOV)

Opalka, K.O.

1989-08-01

The construction of a large test facility has been proposed for simulating the blast and thermal environment resulting from nuclear explosions. This facility would be used to test the survivability and vulnerability of military equipment such as trucks, tanks, and helicopters in a simulated thermal and blast environment, and to perform research into nuclear blast phenomenology. The proposed advanced design concepts, heating of driver gas and fast-acting throat valves for wave shaping, are described and the results of CFD studies to advance these new technical concepts fro simulating decaying blast waves are reported.

Reactivity and Fragmentation of Aluminum-based Structural Energetic Materials under Explosive Loading

NASA Astrophysics Data System (ADS)

Glumac, Nick; Clemenson, Michael; Guadarrama, Jose; Krier, Herman

2015-06-01

Aluminum-cased warheads have been observed to generate enhanced blast and target damage due to reactivity of the aluminum fragments with ambient air. This effect can more than double the output of a conventional warhead. The mechanism by which the aluminum reacts under these conditions remains poorly understood. We undertake a highly controlled experimental study to investigate the phenomenon of aluminum reaction under explosive loading. Experiments are conducted with Al 6061 casings and PBX-N9 explosive with a fixed charge to case mass ratio of 1:2. Results are compared to inert casings (steel), as well as to tests performed in nitrogen environments to isolate aerobic and anaerobic effects. Padded walls are used in some tests to isolate the effects of impact-induced reactions, which are found to be non-negligible. Finally, blast wave measurements and quasi-static pressure measurements are used to isolate the fraction of case reaction that is fast enough to drive the primary blast wave from the later time reaction that generates temperature and overpressure only in the late-time fireball. Fragment size distributions, including those in the micron-scale range, are collected and quantified.

On the formation of Friedlander waves in a compressed-gas-driven shock tube

PubMed Central

Tasissa, Abiy F.; Hautefeuille, Martin; Fitek, John H.; Radovitzky, Raúl A.

2016-01-01

Compressed-gas-driven shock tubes have become popular as a laboratory-scale replacement for field blast tests. The well-known initial structure of the Riemann problem eventually evolves into a shock structure thought to resemble a Friedlander wave, although this remains to be demonstrated theoretically. In this paper, we develop a semi-analytical model to predict the key characteristics of pseudo blast waves forming in a shock tube: location where the wave first forms, peak over-pressure, decay time and impulse. The approach is based on combining the solutions of the two different types of wave interactions that arise in the shock tube after the family of rarefaction waves in the Riemann solution interacts with the closed end of the tube. The results of the analytical model are verified against numerical simulations obtained with a finite volume method. The model furnishes a rational approach to relate shock tube parameters to desired blast wave characteristics, and thus constitutes a useful tool for the design of shock tubes for blast testing. PMID:27118888

Full-scale testing of leakage of blast waves inside a partially vented room exposed to external air blast loading

NASA Astrophysics Data System (ADS)

Codina, R.; Ambrosini, D.

2018-03-01

For the last few decades, the effects of blast loading on structures have been studied by many researchers around the world. Explosions can be caused by events such as industrial accidents, military conflicts or terrorist attacks. Urban centers have been prone to various threats including car bombs, suicide attacks, and improvised explosive devices. Partially vented constructions subjected to external blast loading represent an important topic in protective engineering. The assessment of blast survivability inside structures and the development of design provisions with respect to internal elements require the study of the propagation and leakage of blast waves inside buildings. In this paper, full-scale tests are performed to study the effects of the leakage of blast waves inside a partially vented room that is subjected to different external blast loadings. The results obtained may be useful for proving the validity of different methods of calculation, both empirical and numerical. Moreover, the experimental results are compared with those computed using the empirical curves of the US Defense report/manual UFC 3-340. Finally, results of the dynamic response of the front masonry wall are presented in terms of accelerations and an iso-damage diagram.

Investigation of blast-induced traumatic brain injury.

PubMed

Taylor, Paul A; Ludwigsen, John S; Ford, Corey C

2014-01-01

Many troops deployed in Iraq and Afghanistan have sustained blast-related, closed-head injuries from being within non-lethal distance of detonated explosive devices. Little is known, however, about the mechanisms associated with blast exposure that give rise to traumatic brain injury (TBI). This study attempts to identify the precise conditions of focused stress wave energy within the brain, resulting from blast exposure, which will correlate with a threshold for persistent brain injury. This study developed and validated a set of modelling tools to simulate blast loading to the human head. Using these tools, the blast-induced, early-time intracranial wave motions that lead to focal brain damage were simulated. The simulations predict the deposition of three distinct wave energy components, two of which can be related to injury-inducing mechanisms, namely cavitation and shear. Furthermore, the results suggest that the spatial distributions of these damaging energy components are independent of blast direction. The predictions reported herein will simplify efforts to correlate simulation predictions with clinical measures of TBI and aid in the development of protective headwear.

Investigation of blast-induced traumatic brain injury

PubMed Central

Ludwigsen, John S.; Ford, Corey C.

2014-01-01

Objective Many troops deployed in Iraq and Afghanistan have sustained blast-related, closed-head injuries from being within non-lethal distance of detonated explosive devices. Little is known, however, about the mechanisms associated with blast exposure that give rise to traumatic brain injury (TBI). This study attempts to identify the precise conditions of focused stress wave energy within the brain, resulting from blast exposure, which will correlate with a threshold for persistent brain injury. Methods This study developed and validated a set of modelling tools to simulate blast loading to the human head. Using these tools, the blast-induced, early-time intracranial wave motions that lead to focal brain damage were simulated. Results The simulations predict the deposition of three distinct wave energy components, two of which can be related to injury-inducing mechanisms, namely cavitation and shear. Furthermore, the results suggest that the spatial distributions of these damaging energy components are independent of blast direction. Conclusions The predictions reported herein will simplify efforts to correlate simulation predictions with clinical measures of TBI and aid in the development of protective headwear. PMID:24766453

Modelling and Testing of Blast Effect On the Structures

NASA Astrophysics Data System (ADS)

Figuli, Lucia; Jangl, Štefan; Papán, Daniel

2016-10-01

As a blasting agent in the blasting and mining engineering, has been using one of so called new generation of explosives which offer greater flexibility in their range and application, and such explosive is ANFO. It is type of explosive consists of an oxidiser and a fuel (ammonium nitrate and fuel oil). One of such ANFO explosives which are industrially made in Slovakia is POLONIT. The explosive is a mixture of ammonium nitrate, methyl esters of higher fatty acids, vegetable oil and red dye. The paper deals with the analysis of structure subjected to the blast load created by the explosion of POLONIT charge. First part of paper is describing behaviour and characteristic of blast wave generated from the blast (detonation characteristics, physical characteristics, time-history diagram etc.) and the second part presents the behaviour of such loaded structures, because of the analysis of such dynamical loaded structure is required knowing the parameters of blast wave, its effect on structure and the tools for the solution of dynamic analysis. The real field tests of three different weight of charges and two different structures were done. The explosive POLONIT was used together with 25 g of ignition explosive PLNp10. Analytical and numerical model of blast loaded structure is compared with the results obtained from the field tests (is compared with the corresponding experimental accelerations). For the modelling structures were approximated as a one-degree system of freedom (SDOF), where the blast wave was estimated with linear decay and exponential decay using positive and negative phase of blast wave. Numerical solution of the steel beam dynamic response was performed via FEM (Finite Element Method) using standard software Visual FEA.

Simulation of blast-induced early-time intracranial wave physics leading to traumatic brain injury.

PubMed

Taylor, Paul A; Ford, Corey C

2009-06-01

The objective of this modeling and simulation study was to establish the role of stress wave interactions in the genesis of traumatic brain injury (TBI) from exposure to explosive blast. A high resolution (1 mm3 voxels) five material model of the human head was created by segmentation of color cryosections from the Visible Human Female data set. Tissue material properties were assigned from literature values. The model was inserted into the shock physics wave code, CTH, and subjected to a simulated blast wave of 1.3 MPa (13 bars) peak pressure from anterior, posterior, and lateral directions. Three-dimensional plots of maximum pressure, volumetric tension, and deviatoric (shear) stress demonstrated significant differences related to the incident blast geometry. In particular, the calculations revealed focal brain regions of elevated pressure and deviatoric stress within the first 2 ms of blast exposure. Calculated maximum levels of 15 KPa deviatoric, 3.3 MPa pressure, and 0.8 MPa volumetric tension were observed before the onset of significant head accelerations. Over a 2 ms time course, the head model moved only 1 mm in response to the blast loading. Doubling the blast strength changed the resulting intracranial stress magnitudes but not their distribution. We conclude that stress localization, due to early-time wave interactions, may contribute to the development of multifocal axonal injury underlying TBI. We propose that a contribution to traumatic brain injury from blast exposure, and most likely blunt impact, can occur on a time scale shorter than previous model predictions and before the onset of linear or rotational accelerations traditionally associated with the development of TBI.

Modeling and simulation of blast-induced, early-time intracranial wave physics leading to traumatic brain injury.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ford, Corey C.; Taylor, Paul Allen

The objective of this modeling and simulation study was to establish the role of stress wave interactions in the genesis of traumatic brain injury (TBI) from exposure to explosive blast. A high resolution (1 mm{sup 3} voxels), 5 material model of the human head was created by segmentation of color cryosections from the Visible Human Female dataset. Tissue material properties were assigned from literature values. The model was inserted into the shock physics wave code, CTH, and subjected to a simulated blast wave of 1.3 MPa (13 bars) peak pressure from anterior, posterior and lateral directions. Three dimensional plots ofmore » maximum pressure, volumetric tension, and deviatoric (shear) stress demonstrated significant differences related to the incident blast geometry. In particular, the calculations revealed focal brain regions of elevated pressure and deviatoric (shear) stress within the first 2 milliseconds of blast exposure. Calculated maximum levels of 15 KPa deviatoric, 3.3 MPa pressure, and 0.8 MPa volumetric tension were observed before the onset of significant head accelerations. Over a 2 msec time course, the head model moved only 1 mm in response to the blast loading. Doubling the blast strength changed the resulting intracranial stress magnitudes but not their distribution. We conclude that stress localization, due to early time wave interactions, may contribute to the development of multifocal axonal injury underlying TBI. We propose that a contribution to traumatic brain injury from blast exposure, and most likely blunt impact, can occur on a time scale shorter than previous model predictions and before the onset of linear or rotational accelerations traditionally associated with the development of TBI.« less

Stress Wave Interaction Between Two Adjacent Blast Holes

NASA Astrophysics Data System (ADS)

Yi, Changping; Johansson, Daniel; Nyberg, Ulf; Beyglou, Ali

2016-05-01

Rock fragmentation by blasting is determined by the level and state of stress in the rock mass subjected to blasting. With the application of electronic detonators, some researchers stated that it is possible to achieve improved fragmentation through stress wave superposition with very short delay times. This hypothesis was studied through theoretical analysis in the paper. First, the stress in rock mass induced by a single-hole shot was analyzed with the assumptions of infinite velocity of detonation and infinite charge length. Based on the stress analysis of a single-hole shot, the stress history and tensile stress distribution between two adjacent holes were presented for cases of simultaneous initiation and 1 ms delayed initiation via stress superposition. The results indicated that the stress wave interaction is local around the collision point. Then, the tensile stress distribution at the extended line of two adjacent blast holes was analyzed for a case of 2 ms delay. The analytical results showed that the tensile stress on the extended line increases due to the stress wave superposition under the assumption that the influence of neighboring blast hole on the stress wave propagation can be neglected. However, the numerical results indicated that this assumption is unreasonable and yields contrary results. The feasibility of improving fragmentation via stress wave interaction with precise initiation was also discussed. The analysis in this paper does not support that the interaction of stress waves improves the fragmentation.

Blast wave attenuation in liquid foams: role of gas and evidence of an optimal bubble size.

PubMed

Monloubou, Martin; Bruning, Myrthe A; Saint-Jalmes, Arnaud; Dollet, Benjamin; Cantat, Isabelle

2016-09-28

Liquid foams are excellent systems to mitigate pressure waves such as acoustic or blast waves. The understanding of the underlying dissipation mechanisms however still remains an active matter of debate. In this paper, we investigate the attenuation of a weak blast wave by a liquid foam. The wave is produced with a shock tube and impacts a foam, with a cylindrical geometry. We measure the wave attenuation and velocity in the foam as a function of bubble size, liquid fraction, and the nature of the gas. We show that the attenuation depends on the nature of the gas and we experimentally evidence a maximum of dissipation for a given bubble size. All features are qualitatively captured by a model based on thermal dissipation in the gas.

Double shock front formation in cylindrical radiative blast waves produced by laser irradiation of krypton gas

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kim, I.; Quevedo, H. J.; Feldman, S.

2013-12-15

Radiative blast waves were created by irradiating a krypton cluster source from a supersonic jet with a high intensity femtosecond laser pulse. It was found that the radiation from the shock surface is absorbed in the optically thick upstream medium creating a radiative heat wave that travels supersonically ahead of the main shock. As the blast wave propagates into the heated medium, it slows and loses energy, and the radiative heat wave also slows down. When the radiative heat wave slows down to the transonic regime, a secondary shock in the ionization precursor is produced. This paper presents experimental datamore » characterizing both the initial and secondary shocks and numerical simulations to analyze the double-shock dynamics.« less

Rodent model of direct cranial blast injury.

PubMed

Kuehn, Reed; Simard, Philippe F; Driscoll, Ian; Keledjian, Kaspar; Ivanova, Svetlana; Tosun, Cigdem; Williams, Alicia; Bochicchio, Grant; Gerzanich, Volodymyr; Simard, J Marc

2011-10-01

Traumatic brain injury resulting from an explosive blast is one of the most serious wounds suffered by warfighters, yet the effects of explosive blast overpressure directly impacting the head are poorly understood. We developed a rodent model of direct cranial blast injury (dcBI), in which a blast overpressure could be delivered exclusively to the head, precluding indirect brain injury via thoracic transmission of the blast wave. We constructed and validated a Cranium Only Blast Injury Apparatus (COBIA) to deliver blast overpressures generated by detonating .22 caliber cartridges of smokeless powder. Blast waveforms generated by COBIA replicated those recorded within armored vehicles penetrated by munitions. Lethal dcBI (LD(50) ∼ 515 kPa) was associated with: (1) apparent brainstem failure, characterized by immediate opisthotonus and apnea leading to cardiac arrest that could not be overcome by cardiopulmonary resuscitation; (2) widespread subarachnoid hemorrhages without cortical contusions or intracerebral or intraventricular hemorrhages; and (3) no pulmonary abnormalities. Sub-lethal dcBI was associated with: (1) apnea lasting up to 15 sec, with transient abnormalities in oxygen saturation; (2) very few delayed deaths; (3) subarachnoid hemorrhages, especially in the path of the blast wave; (4) abnormal immunolabeling for IgG, cleaved caspase-3, and β-amyloid precursor protein (β-APP), and staining for Fluoro-Jade C, all in deep brain regions away from the subarachnoid hemorrhages, but in the path of the blast wave; and (5) abnormalities on the accelerating Rotarod that persisted for the 1 week period of observation. We conclude that exposure of the head alone to severe explosive blast predisposes to significant neurological dysfunction.

A Single Primary Blast-Induced Traumatic Brain Injury in a Rodent Model Causes Cell-Type Dependent Increase in Nicotinamide Adenine Dinucleotide Phosphate Oxidase Isoforms in Vulnerable Brain Regions.

PubMed

Rama Rao, Kakulavarapu V; Iring, Stephanie; Younger, Daniel; Kuriakose, Matthew; Skotak, Maciej; Alay, Eren; Gupta, Raj K; Chandra, Namas

2018-06-12

Blast-induced traumatic brain injury (bTBI) is a leading cause of morbidity in soldiers on the battlefield and in training sites with long-term neurological and psychological pathologies. Previous studies from our laboratory demonstrated activation of oxidative stress pathways after blast injury, but their distribution among different brain regions and their impact on the pathogenesis of bTBI have not been explored. The present study examined the protein expression of two isoforms: nicotinamide adenine dinucleotide phosphate (NADPH) oxidase 1 and 2 (NOX1, NOX2), corresponding superoxide production, a downstream event of NOX activation, and the extent of lipid peroxidation adducts of 4-hydroxynonenal (4HNE) to a range of proteins. Brain injury was evaluated 4 h after the shock-wave exposure, and immunofluorescence signal quantification was performed in different brain regions. Expression of NOX isoforms displayed a differential increase in various brain regions: in hippocampus and thalamus, there was the highest increase of NOX1, whereas in the frontal cortex, there was the highest increase of NOX2 expression. Cell-specific analysis of changes in NOX expression with respect to corresponding controls revealed that blast resulted in a higher increase of NOX1 and NOX 2 levels in neurons compared with astrocytes and microglia. Blast exposure also resulted in increased superoxide levels in different brain regions, and such changes were reflected in 4HNE protein adduct formation. Collectively, this study demonstrates that primary blast TBI induces upregulation of NADPH oxidase isoforms in different regions of the brain parenchyma and that neurons appear to be at higher risk for oxidative damage compared with other neural cells.

Simulation of detonation cell kinematics using two-dimensional reactive blast waves

NASA Astrophysics Data System (ADS)

Thomas, G. O.; Edwards, D. H.

1983-10-01

A method of generating a cylindrical blast wave is developed which overcomes the disadvantages inherent in the converging-diverging nozzle technique used by Edwards et al., 1981. It is demonstrated than an exploding wire placed at the apex of a two-dimensional sector provides a satisfactory source of the generation of blast waves in reactive systems. The velocity profiles of the blast waves are found to simulate those in freely propagating detonations very well, and this method does not suffer from the disadvantage of having the mass flow at the throat as in the nozzle method. The density decay parameter is determined to have a constant value of 4 in the systems investigated, and it is suggested that this may be a universal value. It is proposed that suitable wedges could be used to create artificial Mach stems in the same manner as Strehlow and Barthel (1971) without the attendant disadvantages of the nozzle method.

The soft X-ray background as a supernova blast wave viewed from inside - Solar abundance models

NASA Technical Reports Server (NTRS)

Edgar, R. J.

1986-01-01

A model of the soft X-ray background is presented in which the sun is assumed to be inside an active supernova blast wave. The blast wave evolves in a preexisting cavity. The broad band surface brightnesses is explained by such a blast wave with an explosion energy of E sub approximately 5 x 10 to the 50th power ergs and radius 80 to 100 pc, using solar abundances. An approach to treating the problem of large anisotropies in the ambient medium is also explored, accommodating the observed anticorrelation between the soft X-ray surface brightness and the 21 cm column density. It is found that only for post shock temperatures below 10 to the 6 power K a shock propagating into a density enhancement will be dimmer than a similar shock in a lower density region.

Numerical modeling of an experimental shock tube for traumatic brain injury studies

NASA Astrophysics Data System (ADS)

Phillips, Michael; Regele, Jonathan D.

2015-11-01

Unfortunately, Improvised Explosive Devices (IEDs) are encountered commonly by both civilians and military soldiers throughout the world. Over a decade of medical history suggests that traumatic brain injury (TBI) may result from exposure to the blast waves created by these explosions, even if the person does not experience any immediate injury or lose consciousness. Medical researchers study the exposure of mice and rats to blast waves created in specially designed shock tubes to understand the effect on brain tissue. A newly developed table-top shock tube with a short driver section has been developed for mice experiments to reduce the time necessary to administer the blast radiation and increase the amount of statistical information available. In this study, numerical simulations of this shock tube are performed to assess how the blast wave takes its shape. The pressure profiles obtained from the numerical results are compared with the pressure histories from the experimental pressure transducers. The results show differences in behavior from what was expected, but the blast wave may still be an effective means of studying TBI.

Characteristics of laser-induced shock wave injury to the inner ear of rats

NASA Astrophysics Data System (ADS)

Kurioka, Takaomi; Matsunobu, Takeshi; Niwa, Katsuki; Tamura, Atsushi; Kawauchi, Satoko; Satoh, Yasushi; Sato, Shunichi; Shiotani, Akihiro

2014-12-01

Recently, the number of blast injuries of the inner ear has increased in the general population. In blast-induced inner ear injury, a shock wave (SW) component in the blast wave is considered to play an important role in sensorineural hearing loss. However, the mechanisms by which an SW affects inner ear tissue remain largely unknown. We aimed to establish a new animal model for SW-induced inner ear injury by using laser-induced SWs (LISWs) on rats. The LISWs were generated by irradiating an elastic laser target with 694-nm nanosecond pulses of a ruby laser. After LISW application to the cochlea through bone conduction, auditory measurements revealed the presence of inner ear dysfunction, the extent of which depended on LISW overpressure. A significantly lower survival rate of hair cells and spiral ganglion neurons, as well as severe oxidative damage, were observed in the inner ear exposed to an LISW. Although considerable differences in the pressure characteristics exist between LISWs and SWs in real blast waves, the functional and morphological changes shown by the present LISW-based model were similar to those observed in real blast-induced injury. Thus, our animal model is expected to be useful for laboratory-based research of blast-induced inner ear injury.

Characteristics of laser-induced shock wave injury to the inner ear of rats.

PubMed

Kurioka, Takaomi; Matsunobu, Takeshi; Niwa, Katsuki; Tamura, Atsushi; Kawauchi, Satoko; Satoh, Yasushi; Sato, Shunichi; Shiotani, Akihiro

2014-12-01

Recently, the number of blast injuries of the inner ear has increased in the general population. In blast-induced inner ear injury, a shock wave (SW) component in the blast wave is considered to play an important role in sensorineural hearing loss. However, the mechanisms by which an SW affects inner ear tissue remain largely unknown. We aimed to establish a new animal model for SW-induced inner ear injury by using laser-induced SWs (LISWs) on rats. The LISWs were generated by irradiating an elastic laser target with 694-nm nanosecond pulses of a ruby laser. After LISW application to the cochlea through bone conduction, auditory measurements revealed the presence of inner ear dysfunction, the extent of which depended on LISW overpressure. A significantly lower survival rate of hair cells and spiral ganglion neurons, as well as severe oxidative damage, were observed in the inner ear exposed to an LISW. Although considerable differences in the pressure characteristics exist between LISWs and SWs in real blast waves, the functional and morphological changes shown by the present LISW-based model were similar to those observed in real blast-induced injury. Thus, our animal model is expected to be useful for laboratory-based research of blast-induced inner ear injury.

Blast wave mitigation by dry aqueous foams

NASA Astrophysics Data System (ADS)

Del Prete, E.; Chinnayya, A.; Domergue, L.; Hadjadj, A.; Haas, J.-F.

2013-02-01

This paper presents results of experiments and numerical modeling on the mitigation of blast waves using dry aqueous foams. The multiphase formalism is used to model the dry aqueous foam as a dense non-equilibrium two-phase medium as well as its interaction with the high explosion detonation products. New experiments have been performed to study the mass scaling effects. The experimental as well as the numerical results, which are in good agreement, show that more than an order of magnitude reduction in the peak overpressure ratio can be achieved. The positive impulse reduction is less marked than the overpressures. The Hopkinson scaling is also found to hold particularly at larger scales for these two blast parameters. Furthermore, momentum and heat transfers, which have the main dominant role in the mitigation process, are shown to modify significantly the classical blast wave profile and thereafter to disperse the energy from the peak overpressure due to the induced relaxation zone. In addition, the velocity of the fireball, which acts as a piston on its environment, is smaller than in air. Moreover, the greater inertia of the liquid phase tends to project the aqueous foam far from the fireball. The created gap tempers the amplitude of the transmitted shock wave to the aqueous foam. As a consequence, this results in a lowering of blast wave parameters of the two-phase spherical decaying shock wave.

Acceleration from short-duration blast

NASA Astrophysics Data System (ADS)

Ritzel, D. V.; Van Albert, S.; Sajja, V.; Long, J.

2018-01-01

The blast-induced motion of spheres has been studied experimentally where the shock wave is rapidly decaying during the period that quasi-steady acceleration would be developed in the case of a step-function shock wave as considered in most shock-tube studies. The motion of sphere models ranging from 39 to 251 mm in diameter and having a range of densities was assessed using the "free-flight" method in a simulator specially designed to replicate the decaying shock wave profile of spherical blast including negative phase and positive entropy gradient. A standardized blast-wave simulation of 125 kPa and 6-ms positive-phase duration was applied for all experiments. In all cases, there are three phases to the motion: a relatively low "kickoff" velocity from the shock diffraction, acceleration or deceleration during the positive duration, then deceleration through the negative phase and subsequent quiescent air. The unexpected deceleration of larger spheres after their kickoff velocity during the decaying yet high-speed flow of the blast wave seems associated with the persistence of a ring vortex on the downstream side of the sphere. The flow is entirely unsteady with initial forces dominated by the shock diffraction; therefore, the early motion of spheres under such conditions is not governed by quasi-steady drag as in classical aerodynamics. The work will help establish scaling rules for model studies of blast-induced motion relevant to improvised explosive devices, and preliminary results are shown for motion imparted to a human skull surrogate.

Blast-Wave Generation and Propagation in Rapidly Heated Laser-Irradiated Targets

NASA Astrophysics Data System (ADS)

Ivancic, S. T.; Stillman, C. R.; Nilson, P. M.; Solodov, A. A.; Froula, D. H.

2017-10-01

Time-resolved extreme ultraviolet (XUV) spectroscopy was used to study the creation and propagation of a >100-Mbar blast wave in a target irradiated by an intense (>1018WWcm2 cm2) laser pulse. Blast waves provide a platform to generate immense pressures in the laboratory. A temporal double flash of XUV radiation was observed when viewing the rear side of the target, which is attributed to the emergence of a blast wave following rapid heating by a fast-electron beam generated from the laser pulse. The time-history of XUV emission in the photon energy range of 50 to 200 eV was recorded with an x-ray streak camera with 7-ps temporal resolution. The heating and expansion of the target was simulated with an electron transport code coupled to 1-D radiation-hydrodynamics simulations. The temporal delay between the two flashes measured in a systematic study of target thickness and composition was found to evolve in good agreement with a Sedov-Taylor blast-wave solution. This material is based upon work supported by the Department of Energy National Nuclear Security Administration under Award Number DE-NA0001944 and Department of Energy Office of Science Award Number DE-SC-0012317.

Using Building Seismic Strong-Motion Data to Quantify Urban Blast Pressure Fields

NASA Astrophysics Data System (ADS)

Massari, A.; Kohler, M. D.; Heaton, T. H.; Kanamori, H.; Hauksson, E.; Clayton, R. W.; Guy, R.; Bunn, J.; Chandy, M.

2015-12-01

The use of building vibrations to measure blast wave propagation in a city is examined in this case study. The Exxon Mobil Corp. oil refinery in Torrance, California experienced an explosion on February 18, 2015 causing ground shaking equivalent to a magnitude 1.9 earthquake. The impulse response for the source was computed from Southern California Seismic Network data for a multi-orthogonal force system with a value of 2×105 kN vertically downward. The pressure wave excited by the explosion traveled through the city of Los Angeles, and was detected by a dense accelerometer array in a 52-story building also in downtown Los Angeles 22.8 km from the explosion. The array is part of the Community Seismic Network (CSN) and consists of three-component class-C MEMs sensors located on each floor of the building. The detection was verified by the nearly simultaneous arrival times of acceleration pulses on multiple floors of the building, corresponding to an average wave speed near the speed of sound in air. The pressure wave peak magnitude from the air blast was determined using accelerometer data collected on every floor of the building coupled with the elastic response of the structure as a whole. . Making use of high-fidelity finite element modeling of the building validated by previous low-level seismicity and ambient noise data, a procedure is outlined for pressure wave detection and quantification on well instrumented buildings. This case study for a 52 story building, instrumented by the CSN, acts as a proxy for blast wave quantification in dense urban environments. This type of information can be used to understand the flow of blast waves through a cityscape as well as enhance procedures for estimating blast source magnitude. Better understanding of the propagation of pressure waves in urban environments will lead to the development of improved countermeasures in those environments.

Experimental Investigation on the Basic Law of the Fracture Spatial Morphology for Water Pressure Blasting in a Drillhole Under True Triaxial Stress

NASA Astrophysics Data System (ADS)

Huang, Bingxiang; Li, Pengfeng

2015-07-01

The present literature on the morphology of water pressure blasting fractures in drillholes is not sufficient and does not take triaxial confining stress into account. Because the spatial morphology of water pressure blasting fractures in drillholes is not clear, the operations lack an exact basis. Using a large true triaxial water pressure blasting experimental system and an acoustic emission 3-D positioning system, water pressure blasting experiments on cement mortar test blocks (300 mm × 300 mm × 300 mm) were conducted to study the associated basic law of the fracture spatial morphology. The experimental results show that water pressure blasting does not always generate bubble pulsation. After water pressure blasting under true triaxial stress, a crushed compressive zone and a blasting fracture zone are formed from the inside, with the blasting section of the naked drillhole as the center, to the outside. The shape of the outer edges of the two zones is ellipsoidal. The range of the blasting fracture is large in the radial direction of the drillhole, where the surrounding pressure is large, i.e., the range of the blasting fracture in the drillhole radial cross-section is approximately ellipsoidal. The rock near the drillhole wall is affected by a tensile stress wave caused by the test block boundary reflection, resulting in more flake fractures appearing in the fracturing crack surface in the drillhole axial direction and parallel to the boundary surface. The flake fracture is thin, presenting a small-range flake fracture. The spatial morphology of the water pressure blasting fracture in the drillhole along the axial direction is similar to a wide-mouth Chinese bottle: the crack extent is large near the drillhole orifice, gradually narrows inward along the drillhole axial direction, and then increases into an approximate ellipsoid in the internal naked blasting section. Based on the causes of the crack generation, the blasting cracks are divided into three zones: the blasting shock zone, the axial extension zone, and the orifice influence zone. The explosion shock zone is the range that is directly impacted by the explosive shock waves. The axial extension zone is the axial crack area with uniform width, which is formed when the blasting fracture in the edge of the explosion shock zone extends along the drillhole wall. The extension of the orifice influence zone is very large because the explosion stress waves reflect at the free face and generate tensile stress waves. In the water pressure blasting of the drillhole, the sealing section should be lengthened to allow the drillhole blasting cracks to extend sufficiently under the long-time effect of the blasting stress field of quasi-hydrostatic pressure.

Single-subject-based whole-brain MEG slow-wave imaging approach for detecting abnormality in patients with mild traumatic brain injury

PubMed Central

Huang, Ming-Xiong; Nichols, Sharon; Baker, Dewleen G.; Robb, Ashley; Angeles, Annemarie; Yurgil, Kate A.; Drake, Angela; Levy, Michael; Song, Tao; McLay, Robert; Theilmann, Rebecca J.; Diwakar, Mithun; Risbrough, Victoria B.; Ji, Zhengwei; Huang, Charles W.; Chang, Douglas G.; Harrington, Deborah L.; Muzzatti, Laura; Canive, Jose M.; Christopher Edgar, J.; Chen, Yu-Han; Lee, Roland R.

2014-01-01

Traumatic brain injury (TBI) is a leading cause of sustained impairment in military and civilian populations. However, mild TBI (mTBI) can be difficult to detect using conventional MRI or CT. Injured brain tissues in mTBI patients generate abnormal slow-waves (1–4 Hz) that can be measured and localized by resting-state magnetoencephalography (MEG). In this study, we develop a voxel-based whole-brain MEG slow-wave imaging approach for detecting abnormality in patients with mTBI on a single-subject basis. A normative database of resting-state MEG source magnitude images (1–4 Hz) from 79 healthy control subjects was established for all brain voxels. The high-resolution MEG source magnitude images were obtained by our recent Fast-VESTAL method. In 84 mTBI patients with persistent post-concussive symptoms (36 from blasts, and 48 from non-blast causes), our method detected abnormalities at the positive detection rates of 84.5%, 86.1%, and 83.3% for the combined (blast-induced plus with non-blast causes), blast, and non-blast mTBI groups, respectively. We found that prefrontal, posterior parietal, inferior temporal, hippocampus, and cerebella areas were particularly vulnerable to head trauma. The result also showed that MEG slow-wave generation in prefrontal areas positively correlated with personality change, trouble concentrating, affective lability, and depression symptoms. Discussion is provided regarding the neuronal mechanisms of MEG slow-wave generation due to deafferentation caused by axonal injury and/or blockages/limitations of cholinergic transmission in TBI. This study provides an effective way for using MEG slow-wave source imaging to localize affected areas and supports MEG as a tool for assisting the diagnosis of mTBI. PMID:25009772

Relationship between changes in the cochlear blood flow and disorder of hearing function induced by blast injury in guinea pigs.

PubMed

Chen, Wei; Wang, Jianmin; Chen, Jing; Chen, Jichuan; Chen, Zhiqiang

2013-01-01

The auditory system is the most susceptible to damages from blast waves. Blast injuries always lead to varying degrees of hearing impairment. Although a disorder of the cochlear blood flow (CoBF) has been considered to be related to many pathological processes of the auditory system and to contribute to various types of hearing loss, changes in the CoBF induced by blast waves and the relationship between such changes and hearing impairment are undefined. To observe the changes in the cochlear microcirculation after exposure to an explosion blast, investigate the relationship between changes in the CoBF and hearing impairment and subsequently explore the mechanism responsible for the changes in the CoBF, we detected the perfusion of the cochlear microcirculation and hearing threshold shift after exposure to an explosion blast. Then, an N-nitro-L-arginine-methyl ester (L-NAME, NO synthase inhibitor) solution and artificial perilymph were applied to the round window (RW) of the cochlea before the blast exposure, followed by an evaluation of the CoBF and hearing function. The results indicated that the changes in the CoBF were correlated to the strength of the blast wave. The cochlear blood flow significantly increased when the peak value of the blast overpressure was greater than approximately 45 kPa, and there was no significant change in the cochlear blood flow when the peak value of the blast overpressure was less than approximately 35 kPa. Following local administration of the NO synthase inhibitor L-NAME, the increase in the CoBF induced by the blast was inhibited, and this reduction was significantly associated with the hearing threshold.

Localization of small arms fire using acoustic measurements of muzzle blast and/or ballistic shock wave arrivals.

PubMed

Lo, Kam W; Ferguson, Brian G

2012-11-01

The accurate localization of small arms fire using fixed acoustic sensors is considered. First, the conventional wavefront-curvature passive ranging method, which requires only differential time-of-arrival (DTOA) measurements of the muzzle blast wave to estimate the source position, is modified to account for sensor positions that are not strictly collinear (bowed array). Second, an existing single-sensor-node ballistic model-based localization method, which requires both DTOA and differential angle-of-arrival (DAOA) measurements of the muzzle blast wave and ballistic shock wave, is improved by replacing the basic external ballistics model (which describes the bullet's deceleration along its trajectory) with a more rigorous model and replacing the look-up table ranging procedure with a nonlinear (or polynomial) equation-based ranging procedure. Third, a new multiple-sensor-node ballistic model-based localization method, which requires only DTOA measurements of the ballistic shock wave to localize the point of fire, is formulated. The first method is applicable to situations when only the muzzle blast wave is received, whereas the third method applies when only the ballistic shock wave is received. The effectiveness of each of these methods is verified using an extensive set of real data recorded during a 7 day field experiment.

Characterization of Viscoelastic Materials for Low-Magnitude Blast Mitigation

NASA Astrophysics Data System (ADS)

Bartyczak, Susan; Mock, Willis

2013-06-01

Recent preliminary research indicates that exposure to low amplitude blast waves, such as from IED detonation or multiple firings of a weapon, causes damage to brain tissue resulting in Traumatic Brain Injury (TBI) and Post Traumatic Stress Disorder (PTSD). Current combat helmets are not sufficiently protecting warfighters from this danger and the effects are debilitating, costly, and long-lasting. The objective of this research is to evaluate the blast mitigating behavior of current helmet materials and new materials designed for blast mitigation using a test fixture recently developed at the Naval Surface Warfare Center Dahlgren Division for use with an existing gas gun. A 40-mm-bore gas gun is used as a shock tube to generate blast waves (ranging from 5 to 30 psi) in a test fixture mounted at the gun muzzle. A fast opening valve is used to release helium gas from a breech which forms into a blast wave and impacts instrumented targets in the test fixture. Blast attenuation of selected materials is determined through the measurement of pressure and accelerometer data in front of and behind the target. Materials evaluated in this research include 6061-T6 aluminum, polyurea 1000, Styrofoam, and Sorbothane (durometer 50, shore 00). The experimental technique, calibration and checkout procedures, and results will be presented.

MCDU-8-A Computer Code for One-Dimensional Blast Wave Problems

DTIC Science & Technology

1975-07-01

medium surrounding the explosion is assuned to be air obeying an ideal gas equation of state with a constant specific heat ratio, y2, of 1.4. The...characteristics Explosive blast Pentolite spheres ■ 20.\\ASSTRACT (Continue on reverie eld* II neceeemry end Identify by block number) he method...INVOLVING THE. SUDDEN RELEASE OF A HIGHLY COMPRESSED AIR SPHERE 11 V. A SAMPLE PROBLEM INVOLVING A BLAST WAVE RESULTING FROM THE DETONATION OF A

Rapid Simulation of Blast Wave Propagation in Built Environments Using Coarse-Grain Based Intelligent Modeling Methods

DTIC Science & Technology

2011-04-01

experiments was performed using an artificial neural network to try to capture the nonlinearities. The radial Gaussian artificial neural network system...Modeling Blast-Wave Propagation using Artificial Neural Network Methods‖, in International Journal of Advanced Engineering Informatics, Elsevier

Pathophysiology of the inner ear after blast injury caused by laser-induced shock wave

PubMed Central

Niwa, Katsuki; Mizutari, Kunio; Matsui, Toshiyasu; Kurioka, Takaomi; Matsunobu, Takeshi; Kawauchi, Satoko; Satoh, Yasushi; Sato, Shunichi; Shiotani, Akihiro; Kobayashi, Yasushi

2016-01-01

The ear is the organ that is most sensitive to blast overpressure, and ear damage is most frequently seen after blast exposure. Blast overpressure to the ear results in sensorineural hearing loss, which is untreatable and is often associated with a decline in the quality of life. In this study, we used a rat model to demonstrate the pathophysiological and structural changes in the inner ear that replicate pure sensorineural hearing loss associated with blast injury using laser-induced shock wave (LISW) without any conductive hearing loss. Our results indicate that threshold elevation of the auditory brainstem response (ABR) after blast exposure was primarily caused by outer hair cell dysfunction induced by stereociliary bundle disruption. The bundle disruption pattern was unique; disturbed stereocilia were mostly observed in the outermost row, whereas those in the inner and middle rows stereocilia remained intact. In addition, the ABR examination showed a reduction in wave I amplitude without elevation of the threshold in the lower energy exposure group. This phenomenon was caused by loss of the synaptic ribbon. This type of hearing dysfunction has recently been described as hidden hearing loss caused by cochlear neuropathy, which is associated with tinnitus or hyperacusis. PMID:27531021

Pathophysiology of the inner ear after blast injury caused by laser-induced shock wave.

PubMed

Niwa, Katsuki; Mizutari, Kunio; Matsui, Toshiyasu; Kurioka, Takaomi; Matsunobu, Takeshi; Kawauchi, Satoko; Satoh, Yasushi; Sato, Shunichi; Shiotani, Akihiro; Kobayashi, Yasushi

2016-08-17

The ear is the organ that is most sensitive to blast overpressure, and ear damage is most frequently seen after blast exposure. Blast overpressure to the ear results in sensorineural hearing loss, which is untreatable and is often associated with a decline in the quality of life. In this study, we used a rat model to demonstrate the pathophysiological and structural changes in the inner ear that replicate pure sensorineural hearing loss associated with blast injury using laser-induced shock wave (LISW) without any conductive hearing loss. Our results indicate that threshold elevation of the auditory brainstem response (ABR) after blast exposure was primarily caused by outer hair cell dysfunction induced by stereociliary bundle disruption. The bundle disruption pattern was unique; disturbed stereocilia were mostly observed in the outermost row, whereas those in the inner and middle rows stereocilia remained intact. In addition, the ABR examination showed a reduction in wave I amplitude without elevation of the threshold in the lower energy exposure group. This phenomenon was caused by loss of the synaptic ribbon. This type of hearing dysfunction has recently been described as hidden hearing loss caused by cochlear neuropathy, which is associated with tinnitus or hyperacusis.

Simulation and scaling analysis of a spherical particle-laden blast wave

NASA Astrophysics Data System (ADS)

Ling, Y.; Balachandar, S.

2018-02-01

A spherical particle-laden blast wave, generated by a sudden release of a sphere of compressed gas-particle mixture, is investigated by numerical simulation. The present problem is a multiphase extension of the classic finite-source spherical blast-wave problem. The gas-particle flow can be fully determined by the initial radius of the spherical mixture and the properties of gas and particles. In many applications, the key dimensionless parameters, such as the initial pressure and density ratios between the compressed gas and the ambient air, can vary over a wide range. Parametric studies are thus performed to investigate the effects of these parameters on the characteristic time and spatial scales of the particle-laden blast wave, such as the maximum radius the contact discontinuity can reach and the time when the particle front crosses the contact discontinuity. A scaling analysis is conducted to establish a scaling relation between the characteristic scales and the controlling parameters. A length scale that incorporates the initial pressure ratio is proposed, which is able to approximately collapse the simulation results for the gas flow for a wide range of initial pressure ratios. This indicates that an approximate similarity solution for a spherical blast wave exists, which is independent of the initial pressure ratio. The approximate scaling is also valid for the particle front if the particles are small and closely follow the surrounding gas.

Simulation and scaling analysis of a spherical particle-laden blast wave

NASA Astrophysics Data System (ADS)

Ling, Y.; Balachandar, S.

2018-05-01

A spherical particle-laden blast wave, generated by a sudden release of a sphere of compressed gas-particle mixture, is investigated by numerical simulation. The present problem is a multiphase extension of the classic finite-source spherical blast-wave problem. The gas-particle flow can be fully determined by the initial radius of the spherical mixture and the properties of gas and particles. In many applications, the key dimensionless parameters, such as the initial pressure and density ratios between the compressed gas and the ambient air, can vary over a wide range. Parametric studies are thus performed to investigate the effects of these parameters on the characteristic time and spatial scales of the particle-laden blast wave, such as the maximum radius the contact discontinuity can reach and the time when the particle front crosses the contact discontinuity. A scaling analysis is conducted to establish a scaling relation between the characteristic scales and the controlling parameters. A length scale that incorporates the initial pressure ratio is proposed, which is able to approximately collapse the simulation results for the gas flow for a wide range of initial pressure ratios. This indicates that an approximate similarity solution for a spherical blast wave exists, which is independent of the initial pressure ratio. The approximate scaling is also valid for the particle front if the particles are small and closely follow the surrounding gas.

Volcanic Lightning, Pyroclastic Density Currents, Ballistic Fall, Vent Tremor, and One Very Loud Blast: Acoustic Analysis of the 14 July 2013 Vulcanian Eruption at Tungurahua, Ecuador.

NASA Astrophysics Data System (ADS)

Anderson, J.; Johnson, J. B.; Steele, A. L.; Anzieta, J. C.; Ortiz, H. D.; Hall, M. L.; Ruiz, M. C.

2014-12-01

Acoustic recordings reveal a variety of volcanic activities during an exceptionally loud vulcanian eruption at Tungurahua. A period of several months of mild surface activity came to an abrupt end with the emission of a powerful blast wave heard at least 180 km away. Sensors 2080 m from the vent recorded a stepped rise to its maximum overpressure of 1220 Pa (corresponding to a sound pressure level of 156 dB) and its unusually long dominant period of 5.6 s. We discuss source processes that produced the blast wave, considering that wave propagation could be nonlinear near the vent because of high overpressures. More than an hour of acoustic activity was recorded after the blast wave, including sound from falling ballistics, reflections of the blast wave from nearby mountains, pyroclastic density currents, and acoustic tremor at the vent. Glitches in the acoustic records related to plume lightning were also serendipitously observed, although thunder could not be unambiguously identified. We discuss acoustic signatures of falling ballistics and pyroclastic density currents and how array-style deployments and analytic methods can be used to reveal them. Placement of sensors high on the volcano's slopes facilitated resolving these distinct processes. This study demonstrates that near-vent, array-style acoustic installations can be used to monitor various types of volcanic activity.

The characterization and evaluation of accidental explosions

NASA Technical Reports Server (NTRS)

Strehlow, R. A.; Baker, W. E.

1975-01-01

Accidental explosions are discussed from a number of viewpoints. First, all accidental explosions, intentional explosions and natural explosions are characterized by type. Second, the nature of the blast wave produced by an ideal (point source or HE) explosion is discussed to form a basis for describing how other explosion processes yield deviations from ideal blast wave behavior. The current status blast damage mechanism evaluation is also discussed. Third, the current status of our understanding of each different category of accidental explosions is discussed in some detail.

Localization of Gunfire from Multiple Shooters (ARO Research Topic 5.2, Information Processing and Fusion; STIR Program)

DTIC Science & Technology

2016-03-03

for each shot, as well as "raw" data that includes time-of-arrival (TOA) and direction-of-arrival (DOA) of the muzzle blast (MB) produced by the weapon...angle of arrival, muzzle blast, shock wave, bullet deceleration, fusion REPORT DOCUMENTATION PAGE 11. SPONSOR/MONITOR’S REPORT NUMBER(S) 10. SPONSOR...of the muzzle blast (MB) produced by the weapon and the shock wave (SW) produced by the supersonic bullet. The localization accuracy is improved

Leech segmental repeats develop normally in the absence of signals from either anterior or posterior segments

NASA Technical Reports Server (NTRS)

Seaver, E. C.; Shankland, M.

2000-01-01

We have investigated whether the development of segmental repeats is autonomous in the embryo of the leech Helobdella robusta. The segmental tissues of the germinal band arise from progeny of five stem cells called teloblasts. Asymmetric divisions of the teloblasts form chains of segment founder cells (called primary blast cells) that divide in a stereotypical manner to produce differentiated descendants. Using two distinct techniques, we have looked for potential interactions between neighboring blast cell clones along the anterior-posterior axis. In one technique, we prevented the birth of primary blast cells by injection of DNase I into the teloblast, thereby depriving the last blast cell produced before the ablation of its normal posterior neighbors. We also ablated single blast cells with a laser microbeam, which allowed us to assess potential signals acting on either more anterior or more posterior primary blast cell clones. Our results suggest that interactions along the anterior-posterior axis between neighboring primary blast cell clones are not required for development of normal segmental organization within the blast cell clone. We also examined the possibility that blast cells receive redundant signals from both anterior and posterior neighboring clones and that either is sufficient for normal development. Using double blast cell laser ablations to isolate a primary blast cell clone by removal of both its anterior and its posterior neighbor, we found that the isolated clone still develops normally. These results reveal that the fundamental segmental repeat in the leech embryo, the primary blast cell clone, can develop normally in the apparent absence of signals from adjacent repeats along the anterior-posterior axis.

Wound ballistics and blast injuries.

PubMed

Prat, N J; Daban, J-L; Voiglio, E J; Rongieras, F

2017-12-01

Wounds due to gunshot and explosions, while usually observed during battlefield combat, are no longer an exceptional occurrence in civilian practice in France. The principles of wound ballistics are based on the interaction between the projectile and the human body as well as the transfer of energy from the projectile to tissues. The treatment of ballistic wounds relies on several principles: extremity wound debridement and absence of initial closure, complementary medical treatment, routine immobilization, revision surgery and secondary closure. Victims of explosions usually present with a complex clinical picture since injuries are directly or indirectly related to the shock wave (blast) originating from the explosion. These injuries depend on the type of explosive device, the environment and the situation of the victim at the time of the explosion, and are classed as primary, secondary, tertiary or quaternary. Secondary injuries due to flying debris and bomb fragments are generally the predominant presenting symptoms while isolated primary injuries (blast) are rare. The resulting complexity of the clinical picture explains why triage of these victims is particularly difficult. Certain myths, such as inevitable necrosis of the soft tissues that are displaced by the formation of the temporary cavitation by the projectile, or sterilization of the wounds by heat generated by the projectile should be forgotten. Ballistic-protective body armor and helmets are not infallible, even when they are not perforated, and can even be at the origin of injuries, either due to missile impact, or to the blast. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

[An experimental study of blast injury].

PubMed

Wang, Z G

1989-01-01

This paper presents some aspects of the authors' experimental research on blast injury in the past two years. The main results are as follows: (1) A new designed 39 meter-long shock tube for biological test has been built in the laboratory. Its maximal overpressure values are 215 kPa (in open condition) and 505 kPa (in closed condition). It may meet the need for inflicting blast injuries with various degree of severity. (2) A study of the effect of simulating gun muzzle blast wave on sheep indicated that in the single explosion, the threshold overpressure values inflicting the injury of internal organs were: Lung-37.27 kPa, G-I tract-41.0 kPa; the upper respiratory tract-negative until 73 kPa, while in the multiple (20 times) explosions, they were 23.7, 23.7 and 41.4 kPa, respectively. (3) Using TEM, SEM and some other special techniques, such as morphometry, freeze-fracture technique, labelled lanthanum nitrate technique, etc, it was demonstrated that in the lung with blast injury there were significant pathological changes in pulmonary capillary endothelium, alveolar epithelium and their intercellular junctions with apparent increase of permeability. (4) It has been shown that parallel superficial stripelike hemorrhage typical for lung blast injury is "Intercostal marking" instead of "Rib marking". (5) A new type of material (foamy nickel) for protection against blast wave is presented. It was proved that the material can effectively weaken or eliminate the effect of blast wave on human body.

Correlative analysis of head kinematics and brain's tissue response: a computational approach toward understanding the mechanisms of blast TBI

NASA Astrophysics Data System (ADS)

Sarvghad-Moghaddam, H.; Rezaei, A.; Ziejewski, M.; Karami, G.

2017-11-01

Upon impingement of blast waves on the head, stress waves generated at the interface of the skull are transferred into the cranium and the brain tissue and may cause mild to severe blast traumatic brain injury. The intensity of the shock front, defined by the blast overpressure (BoP), that is, the blast-induced peak static overpressure, significantly affects head kinematics as well as the tissue responses of the brain. While evaluation of global linear and rotational accelerations may be feasible, an experimental determination of dynamic responses of the brain in terms of intracranial pressure (ICP), maximum shear stress (MSS), and maximum principal strain (MPS) is almost impossible. The main objective of this study is to investigate possible correlations between head accelerations and the brain's ICP, MSS, and MPS. To this end, three different blasts were simulated by modeling the detonation of 70, 200, and 500 g of TNT at a fixed distance from the head, corresponding to peak BoPs of 0.52, 1.2, and 2 MPa, respectively. A nonlinear multi-material finite element algorithm was implemented in the LS-DYNA explicit solver. Fluid-solid interaction between the blast waves and head was modeled using a penalty-based method. Strong correlations were found between the brain's dynamic responses and both global linear and rotational accelerations at different blast intensities (R^{2 }≥98%), implying that global kinematic parameters of the head might be strong predictors of brain tissue biomechanical parameters.

A Novel Closed-Head Model of Mild Traumatic Brain Injury Caused by Primary Overpressure Blast to the Cranium Produces Sustained Emotional Deficits in Mice

PubMed Central

Heldt, Scott A.; Elberger, Andrea J.; Deng, Yunping; Guley, Natalie H.; Del Mar, Nobel; Rogers, Joshua; Choi, Gy Won; Ferrell, Jessica; Rex, Tonia S.; Honig, Marcia G.; Reiner, Anton

2014-01-01

Emotional disorders are a common outcome from mild traumatic brain injury (TBI) in humans, but their pathophysiological basis is poorly understood. We have developed a mouse model of closed-head blast injury using an air pressure wave delivered to a small area on one side of the cranium, to create mild TBI. We found that 20-psi blasts in 3-month-old C57BL/6 male mice yielded no obvious behavioral or histological evidence of brain injury, while 25–40 psi blasts produced transient anxiety in an open field arena but little histological evidence of brain damage. By contrast, 50–60 psi blasts resulted in anxiety-like behavior in an open field arena that became more evident with time after blast. In additional behavioral tests conducted 2–8 weeks after blast, 50–60 psi mice also demonstrated increased acoustic startle, perseverance of learned fear, and enhanced contextual fear, as well as depression-like behavior and diminished prepulse inhibition. We found no evident cerebral pathology, but did observe scattered axonal degeneration in brain sections from 50 to 60 psi mice 3–8 weeks after blast. Thus, the TBI caused by single 50–60 psi blasts in mice exhibits the minimal neuronal loss coupled to “diffuse” axonal injury characteristic of human mild TBI. A reduction in the abundance of a subpopulation of excitatory projection neurons in basolateral amygdala enriched in Thy1 was, however, observed. The reported link of this neuronal population to fear suppression suggests their damage by mild TBI may contribute to the heightened anxiety and fearfulness observed after blast in our mice. Our overpressure air blast model of concussion in mice will enable further studies of the mechanisms underlying the diverse emotional deficits seen after mild TBI. PMID:24478749

Characterizing the energy output generated by a standard electric detonator using shadowgraph imaging

NASA Astrophysics Data System (ADS)

Petr, V.; Lozano, E.

2017-09-01

This paper overviews a complete method for the characterization of the explosive energy output from a standard detonator. Measurements of the output of explosives are commonly based upon the detonation parameters of the chemical energy content of the explosive. These quantities provide a correct understanding of the energy stored in an explosive, but they do not provide a direct measure of the different modes in which the energy is released. This optically based technique combines high-speed and ultra-high-speed imaging to characterize the casing fragmentation and the detonator-driven shock load. The procedure presented here could be used as an alternative to current indirect methods—such as the Trauzl lead block test—because of its simplicity, high data accuracy, and minimum demand for test repetition. This technique was applied to experimentally measure air shock expansion versus time and calculating the blast wave energy from the detonation of the high explosive charge inside the detonator. Direct measurements of the shock front geometry provide insight into the physics of the initiation buildup. Because of their geometry, standard detonators show an initial ellipsoidal shock expansion that degenerates into a final spherical wave. This non-uniform shape creates variable blast parameters along the primary blast wave. Additionally, optical measurements are validated using piezoelectric pressure transducers. The energy fraction spent in the acceleration of the metal shell is experimentally measured and correlated with the Gurney model, as well as to several empirical formulations for blasts from fragmenting munitions. The fragment area distribution is also studied using digital particle imaging analysis and correlated with the Mott distribution. Understanding the fragmentation distribution plays a critical role when performing hazard evaluation from these types of devices. In general, this technique allows for characterization of the detonator within 6-8% error with no knowledge of the amount or type of explosive contained within the shell, making it also suitable for the study of unknown improvised explosive devices.

Perfluorocarbon reduces cell damage from blast injury by inhibiting signal paths of NF-κB, MAPK and Bcl-2/Bax signaling pathway in A549 cells

PubMed Central

Li, Huaidong; Li, Chunsun; Yang, Zhen; Li, Yanqin; She, Danyang; Cao, Lu; Wang, Wenjie; Liu, Changlin; Chen, Liangan

2017-01-01

Background and objective Blast lung injury is a common type of blast injury and has very high mortality. Therefore, research to identify medical therapies for blast injury is important. Perfluorocarbon (PFC) is used to improve gas exchange in diseased lungs and has anti-inflammatory functions in vitro and in vivo. The aim of this study was to determine whether PFC reduces damage to A549 cells caused by blast injury and to elucidate its possible mechanisms of action. Study design and methods A549 alveolar epithelial cells exposed to blast waves were treated with and without PFC. Morphological changes and apoptosis of A549 cells were recorded. PCR and enzyme-linked immunosorbent assay (ELISA) were used to measure the mRNA or protein levels of IL-1β, IL-6 and TNF-α. Malondialdehyde (MDA) levels and superoxide dismutase (SOD) activity levels were detected. Western blot was used to quantify the expression of NF-κB, Bax, Bcl-2, cleaved caspase-3 and MAPK cell signaling proteins. Results A549 cells exposed to blast wave shrank, with less cell-cell contact. The morphological change of A549 cells exposed to blast waves were alleviated by PFC. PFC significantly inhibited the apoptosis of A549 cells exposed to blast waves. IL-1β, IL-6 and TNF-α cytokine and mRNA expression levels were significantly inhibited by PFC. PFC significantly increased MDA levels and decreased SOD activity levels. Further studies indicated that NF-κB, Bax, caspase-3, phospho-p38, phosphor-ERK and phosphor-JNK proteins were also suppressed by PFC. The quantity of Bcl-2 protein was increased by PFC. Conclusion Our research showed that PFC reduced A549 cell damage caused by blast injury. The potential mechanism may be associated with the following signaling pathways: 1) the signaling pathways of NF-κB and MAPK, which inhibit inflammation and reactive oxygen species (ROS); and 2) the signaling pathways of Bcl-2/Bax and caspase-3, which inhibit apoptosis. PMID:28323898

Characterization of viscoelastic materials for low-magnitude blast mitigation

NASA Astrophysics Data System (ADS)

Bartyczak, S.; Mock, W.

2014-05-01

Recent research indicates that exposure to low amplitude blast waves, such as IED detonation or multiple firings of a weapon, causes damage to brain tissue resulting in Traumatic Brain Injury (TBI) and Post Traumatic Stress Disorder (PTSD). Current combat helmets are not sufficiently protecting warfighters from this danger and the effects are debilitating, costly, and long-lasting. The objective of the present work is to evaluate the blast mitigating behavior of current helmet materials and new materials designed for blast mitigation using a test fixture recently developed at the Naval Surface Warfare Center Dahlgren Division for use with an existing gas gun. The 40-mm-bore gas gun was used as a shock tube to generate blast waves (ranging from 0.5 to 2 bar) in the test fixture mounted on the gun muzzle. A fast opening valve was used to release helium gas from the breech which formed into a blast wave and impacted instrumented targets in the test fixture. Blast attenuation of selected materials was determined through the measurement of stress data in front of and behind the target. Materials evaluated in this research include polyurethane foam from currently fielded US Army and Marine Corps helmets, polyurea 1000, and three hardnesses of Sorbothane (48, 58, and 70 durometer, Shore 00). Polyurea 1000 and 6061-T6 aluminum were used to calibrate the stress gauges.

Mathematical theory of cylindrical isothermal blast waves in a magnetic field. [with application to supernova remnant evolution

NASA Technical Reports Server (NTRS)

Lerche, I.

1981-01-01

An analysis is conducted regarding the properties of cylindrically symmetric self-similar blast waves propagating away from a line source into a medium whose density and magnetic field (with components in both the phi and z directions) both vary as r to the -(omega) power (with omega less than 1) ahead of the blast wave. The main results of the analysis can be divided into two classes, related to a zero azimuthal field and a zero longitudinal field. In the case of the zero longitudinal field it is found that there are no physically acceptable solutions with continuous postshock variations of flow speed and gas density.

Experimental Study of the Effect of Water Mist Location On Blast Overpressure Attenuation in A Shock Tube

NASA Astrophysics Data System (ADS)

Mataradze, Edgar; Chikhradze, Nikoloz; Bochorishvili, Nika; Akhvlediani, Irakli; Tatishvili, Dimitri

2017-12-01

Explosion protection technologies are based on the formation of a shock wave mitigation barrier between the protection site and the explosion site. Contemporary protective systems use water mist as an extinguishing barrier. To achieve high effectiveness of the protective system, proper selection of water mist characteristics is important. The main factors defining shock wave attenuation in water mist include droplet size distribution, water concentration in the mist, droplet velocity and geometric properties of mist. This paper examines the process of attenuation of shock waves in mist with droplets ranging from 25 to 400 microns under different conditions of water mist location. Experiments were conducted at the Mining Institute with the use of a shock tube to study the processes of explosion suppression by a water mist barrier. The shock tube consists of a blast chamber, a tube, a system for the dosed supply of water, sensors, data recording equipment, and a process control module. Shock wave overpressure reduction coefficient was studied in the shock tube under two different locations of water mist: a) when water mist is created in direct contact with blast chamber and b) the blast chamber and the mist are separated by air space. It is established that in conditions when the air space distance between the blast chamber and the mist is 1 meter, overpressure reduction coefficient is 1.5-1.6 times higher than in conditions when water mist is created in direct contact with blast chamber.

Methodology and evaluation of intracranial pressure response in rats exposed to complex shock waves.

PubMed

Dal Cengio Leonardi, Alessandra; Keane, Nickolas J; Hay, Kathryn; Ryan, Anne G; Bir, Cynthia A; VandeVord, Pamela J

2013-12-01

Studies on blast neurotrauma have focused on investigating the effects of exposure to free-field blast representing the simplest form of blast threat scenario without considering any reflecting surfaces. However, in reality personnel are often located within enclosures or nearby reflecting walls causing a complex blast environment, that is, involving shock reflections and/or compound waves from different directions. The purpose of this study was to design a complex wave testing system and perform a preliminary investigation of the intracranial pressure (ICP) response of rats exposed to a complex blast wave environment (CBWE). The effects of head orientation in the same environment were also explored. Furthermore, since it is hypothesized that exposure to a CBWE would be more injurious as compared to a free-field blast wave environment (FFBWE), a histological comparison of hippocampal injury (cleaved caspase-3 and glial fibrillary acidic protein (GFAP)) was conducted in both environments. Results demonstrated that, regardless of orientation, peak ICP values were significantly elevated over the peak static air overpressure. Qualitative differences could be noticed compared to the ICP response in rats exposed to simulated FFBWE. In the CBWE scenario, after the initial loading the skull/brain system was not allowed to return to rest and was loaded again reaching high ICP values. Furthermore, results indicated consistent and distinct ICP-time profiles according to orientation, as well as distinctive values of impulse associated with each orientation. Histologically, cleaved caspase-3 positive cells were significantly increased in the CBWE as compared to the FFBWE. Overall, these findings suggest that the geometry of the skull and the way sutures are distributed in the rats are responsible for the difference in the stresses observed. Moreover, this increase stress contributes to correlation of increased injury in the CBWE.

A Novel Closed-Head Model of Mild Traumatic Brain Injury Using Focal Primary Overpressure Blast to the Cranium in Mice

PubMed Central

Guley, Natalie H.; Rogers, Joshua T.; Del Mar, Nobel A.; Deng, Yunping; Islam, Rafiqul M.; D'Surney, Lauren; Ferrell, Jessica; Deng, Bowei; Hines-Beard, Jessica; Bu, Wei; Ren, Huiling; Elberger, Andrea J.; Marchetta, Jeffrey G.; Rex, Tonia S.; Honig, Marcia G.

2016-01-01

Abstract Mild traumatic brain injury (TBI) from focal head impact is the most common form of TBI in humans. Animal models, however, typically use direct impact to the exposed dura or skull, or blast to the entire head. We present a detailed characterization of a novel overpressure blast system to create focal closed-head mild TBI in mice. A high-pressure air pulse limited to a 7.5 mm diameter area on the left side of the head overlying the forebrain is delivered to anesthetized mice. The mouse eyes and ears are shielded, and its head and body are cushioned to minimize movement. This approach creates mild TBI by a pressure wave that acts on the brain, with minimal accompanying head acceleration-deceleration. A single 20-psi blast yields no functional deficits or brain injury, while a single 25–40 psi blast yields only slight motor deficits and brain damage. By contrast, a single 50–60 psi blast produces significant visual, motor, and neuropsychiatric impairments and axonal damage and microglial activation in major fiber tracts, but no contusive brain injury. This model thus reproduces the widespread axonal injury and functional impairments characteristic of closed-head mild TBI, without the complications of systemic or ocular blast effects or head acceleration that typically occur in other blast or impact models of closed-skull mild TBI. Accordingly, our model provides a simple way to examine the biomechanics, pathophysiology, and functional deficits that result from TBI and can serve as a reliable platform for testing therapies that reduce brain pathology and deficits. PMID:26414413

Distinguishing Realistic Military Blasts from Firecrackers in Mitigation Studies of Blast Induced Traumatic Brain Injury

DOE Office of Scientific and Technical Information (OSTI.GOV)

Moss, W C; King, M J; Blackman, E G

In their Contributed Article, Nyein et al. (1,2) present numerical simulations of blast waves interacting with a helmeted head and conclude that a face shield may significantly mitigate blast induced traumatic brain injury (TBI). A face shield may indeed be important for future military helmets, but the authors derive their conclusions from a much smaller explosion than typically experienced on the battlefield. The blast from the 3.16 gm TNT charge of (1) has the following approximate peak overpressures, positive phase durations, and incident impulses (3): 10 atm, 0.25 ms, and 3.9 psi-ms at the front of the head (14 cmmore » from charge), and 1.4 atm, 0.32 ms, and 1.7 psi-ms at the back of a typical 20 cm head (34 cm from charge). The peak pressure of the wave decreases by a factor of 7 as it traverses the head. The blast conditions are at the threshold for injury at the front of the head, but well below threshold at the back of the head (4). The blast traverses the head in 0.3 ms, roughly equal to the positive phase duration of the blast. Therefore, when the blast reaches the back of the head, near ambient conditions exist at the front. Because the headform is so close to the charge, it experiences a wave with significant curvature. By contrast, a realistic blast from a 2.2 kg TNT charge ({approx} an uncased 105 mm artillery round) is fatal at an overpressure of 10 atm (4). For an injury level (4) similar to (1), a 2.2 kg charge has the following approximate peak overpressures, positive phase durations, and incident impulses (3): 2.1 atm, 2.3 ms, and 18 psi-ms at the front of the head (250 cm from charge), and 1.8 atm, 2.5 ms, and 16.8 psi-ms at the back of the head (270 cm from charge). The peak pressure decreases by only a factor of 1.2 as it traverses the head. Because the 0.36 ms traversal time is much smaller than the positive phase duration, pressures on the head become relatively uniform when the blast reaches the back of the head. The larger standoff implies that the headform locally experiences a nearly planar blast wave. Also, the positive phase durations and blast impulses are much larger than those of (1). Consequently, the blast model used in (1) is spatially and temporally very different from a military blast. It would be useful to repeat the calculations using military blast parameters. Finally, (1) overlooks a significant part of (5). On page 1 and on page 3, (1) states that (5) did not consider helmet pads. But pages pages 3 and 4 of (5) present simulations of blast wave propagation across an ACH helmeted head form with and without pads. (5) states that when the pads are present, the 'underwash' of air under the helmet is blocked when compared to the case without. (1) reaches this same conclusion, but reports it as a new result rather than a confirmation of that already found in (5).« less

Effect of Human and Sheep Lung Orientation on Primary Blast Injury Induced by Single Blast

DTIC Science & Technology

2010-09-01

may be injured by m ore than one of these mechanisms in any given event. Primary blast in juries ( PBI ) are exclusively caused by the blast...overpressure. A PBI usually affects air-containing organs such as t he lung, ears and gastrointestinal tract. Secon dary blast injuries are caused by...orientation on blast injuries predicted in human and sheep models. From th is study, it is predicted that the greatest reduction in lung PBI may be

Piecewise parabolic method for simulating one-dimensional shear shock wave propagation in tissue-mimicking phantoms

NASA Astrophysics Data System (ADS)

Tripathi, B. B.; Espíndola, D.; Pinton, G. F.

2017-11-01

The recent discovery of shear shock wave generation and propagation in the porcine brain suggests that this new shock phenomenology may be responsible for a broad range of traumatic injuries. Blast-induced head movement can indirectly lead to shear wave generation in the brain, which could be a primary mechanism for injury. Shear shock waves amplify the local acceleration deep in the brain by up to a factor of 8.5, which may tear and damage neurons. Currently, there are numerical methods that can model compressional shock waves, such as comparatively well-studied blast waves, but there are no numerical full-wave solvers that can simulate nonlinear shear shock waves in soft solids. Unlike simplified representations, e.g., retarded time, full-wave representations describe fundamental physical behavior such as reflection and heterogeneities. Here we present a piecewise parabolic method-based solver for one-dimensional linearly polarized nonlinear shear wave in a homogeneous medium and with empirical frequency-dependent attenuation. This method has the advantage of being higher order and more directly extendable to multiple dimensions and heterogeneous media. The proposed numerical scheme is validated analytically and experimentally and compared to other shock capturing methods. A Riemann step-shock problem is used to characterize the numerical dissipation. This dissipation is then tuned to be negligible with respect to the physical attenuation by choosing an appropriate grid spacing. The numerical results are compared to ultrasound-based experiments that measure planar polarized shear shock wave propagation in a tissue-mimicking gelatin phantom. Good agreement is found between numerical results and experiment across a 40 mm propagation distance. We anticipate that the proposed method will be a starting point for the development of a two- and three-dimensional full-wave code for the propagation of nonlinear shear waves in heterogeneous media.

Direct Comparison of the Primary Blast Response of a Physical Head Model with Post-mortem Human Subjects

DTIC Science & Technology

2014-02-27

and brain st e made from erpart. The br ace by the me is instrumen design sleev sure transduc se of the tria f the gel duri is in intima pically...filtered usin ressure signa with the hea a 10 kHz cu ty of WSU u series. The sh section sepa p to a pressu wave down re pressure a design can be...of wave generat 5m (0 ouring of the he occipital s e comparativ hod used in t tterworth filt llowing the s d of a filterin tudy (Figure o part

Anatomical manifestations of primary blast ocular trauma observed in a postmortem porcine model.

PubMed

Sherwood, Daniel; Sponsel, William E; Lund, Brian J; Gray, Walt; Watson, Richard; Groth, Sylvia L; Thoe, Kimberly; Glickman, Randolph D; Reilly, Matthew A

2014-02-24

We qualitatively describe the anatomic features of primary blast ocular injury observed using a postmortem porcine eye model. Porcine eyes were exposed to various levels of blast energy to determine the optimal conditions for future testing. We studied 53 enucleated porcine eyes: 13 controls and 40 exposed to a range of primary blast energy levels. Eyes were preassessed with B-scan and ultrasound biomicroscopy (UBM) ultrasonography, photographed, mounted in gelatin within acrylic orbits, and monitored with high-speed videography during blast-tube impulse exposure. Postimpact photography, ultrasonography, and histopathology were performed, and ocular damage was assessed. Evidence for primary blast injury was obtained. While some of the same damage was observed in the control eyes, the incidence and severity of this damage in exposed eyes increased with impulse and peak pressure, suggesting that primary blast exacerbated these injuries. Common findings included angle recession, internal scleral delamination, cyclodialysis, peripheral chorioretinal detachments, and radial peripapillary retinal detachments. No full-thickness openings of the eyewall were observed in any of the eyes tested. Scleral damage demonstrated the strongest associative tendency for increasing likelihood of injury with increased overpressure. These data provide evidence that primary blast alone (in the absence of particle impact) can produce clinically relevant ocular damage in a postmortem model. The blast parameters derived from this study are being used currently in an in vivo model. We also propose a new Cumulative Injury Score indicating the clinical relevance of observed injuries.

Quarry blasts assessment and their environmental impacts on the nearby oil pipelines, southeast of Helwan City, Egypt

NASA Astrophysics Data System (ADS)

Mohamed, Adel M. E.; Mohamed, Abuo El-Ela A.

2013-06-01

Ground vibrations induced by blasting in the cement quarries are one of the fundamental problems in the quarrying industry and may cause severe damage to the nearby utilities and pipelines. Therefore, a vibration control study plays an important role in the minimization of environmental effects of blasting in quarries. The current paper presents the influence of the quarry blasts at the National Cement Company (NCC) on the two oil pipelines of SUMED Company southeast of Helwan City, by measuring the ground vibrations in terms of Peak Particle Velocity (PPV). The seismic refraction for compressional waves deduced from the shallow seismic survey and the shear wave velocity obtained from the Multi channel Analysis of Surface Waves (MASW) technique are used to evaluate the closest site of the two pipelines to the quarry blasts. The results demonstrate that, the closest site of the two pipelines is of class B, according to the National Earthquake Hazard Reduction Program (NEHRP) classification and the safe distance to avoid any environmental effects is 650 m, following the deduced Peak Particle Velocity (PPV) and scaled distance (SD) relationship (PPV = 700.08 × SD-1.225) in mm/s and the Air over Pressure (air blast) formula (air blast = 170.23 × SD-0.071) in dB. In the light of prediction analysis, the maximum allowable charge weight per delay was found to be 591 kg with damage criterion of 12.5 mm/s at the closest site of the SUMED pipelines.

Chemical Initiation of FAE Clouds

DTIC Science & Technology

1980-11-01

iadlded significant FAE blasts when performed in open air, no blasl when performed in an atmosphere of nitrogen, and a very strong blast when per...miniature experiments produced well-measurable blast pressures which were considerably larger when the ambient atmosphere was air instead of nitrogen, and...very much larger when the ambient atmosphere was oxygen. It was thus demonstrated that the blast wave is reinforced by release of combustion energy

Blast and Shock Mitigation Through the Use of Advanced Materials

NASA Astrophysics Data System (ADS)

Bartyczak, Susan; Edgerton, Lauren; Mock, Willis

2017-06-01

The dynamic response to low amplitude blast waves of four viscoelastic materials has been investigated: Dragonshield BCTM and three polyurea formulations (P1000, P650, and a P250/1000 blend). A 40-mm-bore gas gun was used as a shock tube to generate planar blast waves, ranging from 1 to 2 bars, that impacted instrumented target assemblies mounted on the gas gun muzzle. Each target assembly consisted of a viscoelastic material sample sandwiched between two gauge assemblies for measuring wave velocity and input/output stresses. Each gauge assembly consisted of one polyvinylidene fluoride (PVDF) stress gauge sandwiched between two 3.25 inch diameter 6061-T6 aluminum discs. Impedance matching techniques were used on the stress measurements to calculate the stresses on the front and back of the samples. The shock velocity-particle velocity relationship, stress-particle velocity relationship, and blast attenuation for each material were determined. The experimental technique, analysis methodology, and results will be presented.

Extended adiabatic blast waves and a model of the soft X-ray background. [interstellar matter

NASA Technical Reports Server (NTRS)

Cox, D. P.; Anderson, P. R.

1981-01-01

An analytical approximation is generated which follows the development of an adiabatic spherical blast wave in a homogeneous ambient medium of finite pressure. An analytical approximation is also presented for the electron temperature distribution resulting from coulomb collisional heating. The dynamical, thermal, ionization, and spectral structures are calculated for blast waves of energy E sub 0 = 5 x 10 to the 50th power ergs in a hot low-density interstellar environment. A formula is presented for estimating the luminosity evolution of such explosions. The B and C bands of the soft X-ray background, it is shown, are reproduced by such a model explosion if the ambient density is about .000004 cm, the blast radius is roughly 100 pc, and the solar system is located inside the shocked region. Evolution in a pre-existing cavity with a strong density gradient may, it is suggested, remove both the M band and OVI discrepancies.

Computational Modeling of Blast Wave Transmission Through Human Ear.

PubMed

Leckness, Kegan; Nakmali, Don; Gan, Rong Z

2018-03-01

Hearing loss has become the most common disability among veterans. Understanding how blast waves propagate through the human ear is a necessary step in the development of effective hearing protection devices (HPDs). This article presents the first 3D finite element (FE) model of the human ear to simulate blast wave transmission through the ear. The 3D FE model of the human ear consisting of the ear canal, tympanic membrane, ossicular chain, and middle ear cavity was imported into ANSYS Workbench for coupled fluid-structure interaction analysis in the time domain. Blast pressure waveforms recorded external to the ear in human cadaver temporal bone tests were applied at the entrance of the ear canal in the model. The pressure waveforms near the tympanic membrane (TM) in the canal (P1) and behind the TM in the middle ear cavity (P2) were calculated. The model-predicted results were then compared with measured P1 and P2 waveforms recorded in human cadaver ears during blast tests. Results show that the model-derived P1 waveforms were in an agreement with the experimentally recorded waveforms with statistic Kurtosis analysis. The FE model will be used for the evaluation of HPDs in future studies.

Self-similar relativistic blast waves with energy injection

NASA Astrophysics Data System (ADS)

van Eerten, Hendrik

2014-08-01

A sufficiently powerful astrophysical source with power-law luminosity in time will give rise to a self-similar relativistic blast wave with a reverse shock travelling into the ejecta and a forward shock moving into the surrounding medium. Once energy injection ceases and the last energy is delivered to the shock front, the blast wave will transit into another self-similar stage depending only on the total amount of energy injected. I describe the effect of limited duration energy injection into environments with density depending on radius as a power law, emphasizing optical/X-ray Gamma-ray Burst afterglows as applications. The blast wave during injection is treated analytically, the transition following last energy injection with one-dimensional simulations. Flux equations for synchrotron emission from the forward and reverse shock regions are provided. The reverse shock emission can easily dominate, especially with different magnetizations for both regions. Reverse shock emission is shown to support both the reported X-ray and optical correlations between afterglow plateau duration and end time flux, independently of the luminosity power-law slope. The model is demonstrated by application to bursts 120521A and 090515, and can accommodate their steep post-plateau light-curve slopes.

No Flares from Gamma-Ray Burst Afterglow Blast Waves Encountering Sudden Circumburst Density Change

NASA Astrophysics Data System (ADS)

Gat, Ilana; van Eerten, Hendrik; MacFadyen, Andrew

2013-08-01

Afterglows of gamma-ray bursts are observed to produce light curves with the flux following power-law evolution in time. However, recent observations reveal bright flares at times on the order of minutes to days. One proposed explanation for these flares is the interaction of a relativistic blast wave with a circumburst density transition. In this paper, we model this type of interaction computationally in one and two dimensions, using a relativistic hydrodynamics code with adaptive mesh refinement called RAM, and analytically in one dimension. We simulate a blast wave traveling in a stellar wind environment that encounters a sudden change in density, followed by a homogeneous medium, and compute the observed radiation using a synchrotron model. We show that flares are not observable for an encounter with a sudden density increase, such as a wind termination shock, nor for an encounter with a sudden density decrease. Furthermore, by extending our analysis to two dimensions, we are able to resolve the spreading, collimation, and edge effects of the blast wave as it encounters the change in circumburst medium. In all cases considered in this paper, we find that a flare will not be observed for any of the density changes studied.

Relationship between Orientation to a Blast and Pressure Wave Propagation Inside the Rat Brian

DTIC Science & Technology

2011-01-01

8217·’ 2.9 ± 0.4’ ·• 64 M. Chavko ec at. I j ournal of Neuroscience Mecl1ods 195 (20!1 ) 61-66 A 60 ~ c 60 ~ ------> ------> 40 40 ~ 20 20 v :; VI...WA, Prusaczyk WK. McCarron RM. Measurement or blast wave by a miniature fiber optic pressure transducer in the rat brain. J Neurosci Methods...AI. Blast related neuro- trauma: a review or cellular injury. Mol Cell Biomech 2008;3: 155-68. ling G. Bandak F, Armonda R, Grant G, Ecklund J

Effects of Low-Level Blast Exposure on the Nervous System: Is There Really a Controversy?

PubMed Central

Elder, Gregory A.; Stone, James R.; Ahlers, Stephen T.

2014-01-01

High-pressure blast waves can cause extensive CNS injury in human beings. However, in combat settings, such as Iraq and Afghanistan, lower level exposures associated with mild traumatic brain injury (mTBI) or subclinical exposure have been much more common. Yet controversy exists concerning what traits can be attributed to low-level blast, in large part due to the difficulty of distinguishing blast-related mTBI from post-traumatic stress disorder (PTSD). We describe how TBI is defined in human beings and the problems posed in using current definitions to recognize blast-related mTBI. We next consider the problem of applying definitions of human mTBI to animal models, in particular that TBI severity in human beings is defined in relation to alteration of consciousness at the time of injury, which typically cannot be assessed in animals. However, based on outcome assessments, a condition of “low-level” blast exposure can be defined in animals that likely approximates human mTBI or subclinical exposure. We review blast injury modeling in animals noting that inconsistencies in experimental approach have contributed to uncertainty over the effects of low-level blast. Yet, animal studies show that low-level blast pressure waves are transmitted to the brain. In brain, low-level blast exposures cause behavioral, biochemical, pathological, and physiological effects on the nervous system including the induction of PTSD-related behavioral traits in the absence of a psychological stressor. We review the relationship of blast exposure to chronic neurodegenerative diseases noting the paradoxical lowering of Abeta by blast, which along with other observations suggest that blast-related TBI is pathophysiologically distinct from non-blast TBI. Human neuroimaging studies show that blast-related mTBI is associated with a variety of chronic effects that are unlikely to be explained by co-morbid PTSD. We conclude that abundant evidence supports low-level blast as having long-term effects on the nervous system. PMID:25566175

An animal-to-human scaling law for blast-induced traumatic brain injury risk assessment.

PubMed

Jean, Aurélie; Nyein, Michelle K; Zheng, James Q; Moore, David F; Joannopoulos, John D; Radovitzky, Raúl

2014-10-28

Despite recent efforts to understand blast effects on the human brain, there are still no widely accepted injury criteria for humans. Recent animal studies have resulted in important advances in the understanding of brain injury due to intense dynamic loads. However, the applicability of animal brain injury results to humans remains uncertain. Here, we use advanced computational models to derive a scaling law relating blast wave intensity to the mechanical response of brain tissue across species. Detailed simulations of blast effects on the brain are conducted for different mammals using image-based biofidelic models. The intensity of the stress waves computed for different external blast conditions is compared across species. It is found that mass scaling, which successfully estimates blast tolerance of the thorax, fails to capture the brain mechanical response to blast across mammals. Instead, we show that an appropriate scaling variable must account for the mass of protective tissues relative to the brain, as well as their acoustic impedance. Peak stresses transmitted to the brain tissue by the blast are then shown to be a power function of the scaling parameter for a range of blast conditions relevant to TBI. In particular, it is found that human brain vulnerability to blast is higher than for any other mammalian species, which is in distinct contrast to previously proposed scaling laws based on body or brain mass. An application of the scaling law to recent experiments on rabbits furnishes the first physics-based injury estimate for blast-induced TBI in humans.

RESONANT AMPLIFICATION OF TURBULENCE BY THE BLAST WAVES

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zankovich, A. M.; Kovalenko, I. G., E-mail: ilya.g.kovalenko@gmail.com

2015-02-10

We discuss the idea of whether spherical blast waves can amplify by a nonlocal resonant hydrodynamic mechanism inhomogeneities formed by turbulence or phase segregation in the interstellar medium. We consider the problem of a blast-wave-turbulence interaction in the Linear Interaction Approximation. Mathematically, this is an eigenvalue problem for finding the structure and amplitude of eigenfunctions describing the response of the shock-wave flow to forced oscillations by external perturbations in the ambient interstellar medium. Linear analysis shows that the blast wave can amplify density and vorticity perturbations for a wide range of length scales with amplification coefficients of up to 20,more » with increasing amplification the larger the length. There also exist resonant harmonics for which the gain becomes formally infinite in the linear approximation. Their orbital wavenumbers are within the range of macro- (l ∼ 1), meso- (l ∼ 20), and microscopic (l > 200) scales. Since the resonance width is narrow (typically, Δl < 1), resonance should select and amplify discrete isolated harmonics. We speculate on a possible explanation of an observed regular filamentary structure of regularly shaped round supernova remnants such as SNR 1572, 1006, or 0509-67.5. Resonant mesoscales found (l ≈ 18) are surprisingly close to the observed scales (l ≈ 15) of ripples in the shell's surface of SNR 0509-67.5.« less

Multi-thermal observations of the 2010 October 16 flare:heating of a ribbon via loops, or a blast wave?

NASA Astrophysics Data System (ADS)

Christe, Steven; Inglis, A.; Aschwanden, M.; Dennis, B.

2011-05-01

On 2010 October 16th SDO/AIA observed its first flare using automatic exposure control. Coincidentally, this flare also exhibited a large number of interesting features. Firstly, a large ribbon significantly to the solar west of the flare kernel was ignited and was visible in all AIA wavelengths, posing the question as to how this energy was deposited and how it relates to the main flare site. A faint blast wave also emanates from the flare kernel, visible in AIA and observed traveling to the solar west at an estimated speed of 1000 km/s. This blast wave is associated with a weak white-light CME observed with STEREO B and a Type II radio burst observed from Green Bank Observatory (GBSRBS). One possibility is that this blast wave is responsible for the heating of the ribbon. However, closer scrutiny reveals that the flare site and the ribbon are in fact connected magnetically via coronal loops which are heated during the main energy release. These loops are distinct from the expected hot, post-flare loops present within the main flare kernel. RHESSI spectra indicate that these loops are heated to approximately 10 MK in the immediate flare aftermath. Using the multi-temperature capabilities of AIA in combination with RHESSI, and by employing the cross-correlation mapping technique, we are able to measure the loop temperatures as a function of time over several post-flare hours and hence measure the loop cooling rate. We find that the time delay between the appearance of loops in the hottest channel, 131 A, and the cool 171 A channel, is 70 minutes. Yet the causality of this event remains unclear. Is the ribbon heated via these interconnected loops or via a blast wave?

Prediction of air blast mitigation in an array of rigid obstacles using smoothed particle hydrodynamics

NASA Astrophysics Data System (ADS)

Prasanna Kumar, S. S.; Patnaik, B. S. V.; Ramamurthi, K.

2018-04-01

The mitigation of blast waves propagating in air and interacting with rigid barriers and obstacles is numerically investigated using the mesh-free smoothed particle hydrodynamics method. A novel virtual boundary particle procedure with a skewed gradient wall boundary treatment is applied at the interfaces between air and rigid bodies. This procedure is validated with closed-form solutions for strong and weak shock reflection from rigid surfaces, supersonic flows over a wedge, formation of reflected, transverse, and Mach stem shocks, and also earlier experiments on interaction of a blast wave with concrete blocks. The mitigation of the overpressure and impulse transmitted to the protected structure due to an array of rigid obstacles of different shapes placed in the path of the blast wave is thereafter determined and discussed in the context of the existing experimental and numerical studies. It is shown that blockages having the shape of a right facing triangle or square placed in tandem or staggered provide better mitigation. The influence of the distance between the blockage array and protected structure is assessed, and the incorporation of a gap in the blockages is shown to improve the mitigation. The mechanisms responsible for the attenuation of air blast are identified through the simulations.

Off-center blast in a shocked medium

DOE PAGES

Duncan-Miller, Gabrielle Christiane; Stone, William D.

2017-11-16

When multiple blasts occur at different times, the situation arises in which a blast wave is propagating into a medium that has already been shocked. Determining the evolution in shape of the second shock is not trivial, as it is propagating into air that is not only non-uniform, but also non-stationary. To accomplish this task, we employ the method of Kompaneets to determine the shape of a shock in a non-uniform media. We also draw from the work of Korycansky [1] on an off-center explosion in a medium with radially varying density. Extending this to treat non-stationary flow, and makingmore » use of approximations to the Sedov solution for the point blast problem, we are able to determine an analytic expression for the evolving shape of the second shock. Specifically, we consider the case of a shock in air at standard ambient temperature and pressure, with the second shock occurring shortly after the original blast wave reaches it, as in a sympathetic detonation.« less

Air blast injuries killed the crew of the submarine H.L. Hunley.

PubMed

Lance, Rachel M; Stalcup, Lucas; Wojtylak, Brad; Bass, Cameron R

2017-01-01

The submarine H.L. Hunley was the first submarine to sink an enemy ship during combat; however, the cause of its sinking has been a mystery for over 150 years. The Hunley set off a 61.2 kg (135 lb) black powder torpedo at a distance less than 5 m (16 ft) off its bow. Scaled experiments were performed that measured black powder and shock tube explosions underwater and propagation of blasts through a model ship hull. This propagation data was used in combination with archival experimental data to evaluate the risk to the crew from their own torpedo. The blast produced likely caused flexion of the ship hull to transmit the blast wave; the secondary wave transmitted inside the crew compartment was of sufficient magnitude that the calculated chances of survival were less than 16% for each crew member. The submarine drifted to its resting place after the crew died of air blast trauma within the hull.

Off-center blast in a shocked medium

DOE Office of Scientific and Technical Information (OSTI.GOV)

Duncan-Miller, Gabrielle Christiane; Stone, William D.

When multiple blasts occur at different times, the situation arises in which a blast wave is propagating into a medium that has already been shocked. Determining the evolution in shape of the second shock is not trivial, as it is propagating into air that is not only non-uniform, but also non-stationary. To accomplish this task, we employ the method of Kompaneets to determine the shape of a shock in a non-uniform media. We also draw from the work of Korycansky [1] on an off-center explosion in a medium with radially varying density. Extending this to treat non-stationary flow, and makingmore » use of approximations to the Sedov solution for the point blast problem, we are able to determine an analytic expression for the evolving shape of the second shock. Specifically, we consider the case of a shock in air at standard ambient temperature and pressure, with the second shock occurring shortly after the original blast wave reaches it, as in a sympathetic detonation.« less

Air blast injuries killed the crew of the submarine H.L. Hunley

PubMed Central

Stalcup, Lucas; Wojtylak, Brad; Bass, Cameron R.

2017-01-01

The submarine H.L. Hunley was the first submarine to sink an enemy ship during combat; however, the cause of its sinking has been a mystery for over 150 years. The Hunley set off a 61.2 kg (135 lb) black powder torpedo at a distance less than 5 m (16 ft) off its bow. Scaled experiments were performed that measured black powder and shock tube explosions underwater and propagation of blasts through a model ship hull. This propagation data was used in combination with archival experimental data to evaluate the risk to the crew from their own torpedo. The blast produced likely caused flexion of the ship hull to transmit the blast wave; the secondary wave transmitted inside the crew compartment was of sufficient magnitude that the calculated chances of survival were less than 16% for each crew member. The submarine drifted to its resting place after the crew died of air blast trauma within the hull. PMID:28832592

Pressure pulse induced-damage in live biological samples

NASA Astrophysics Data System (ADS)

Bo, C.; Balzer, J.; Godfrey, S.; Francois, M.; Saffell, J. L.; Rankin, S. M.; Proud, W. G.; Brown, K. A.

2012-08-01

Developing a cellular and molecular understanding of the nature of traumatic and post-traumatic effects of blast on live biological samples is critical for improving clinical outcomes. To analyze the effects of blast waves upon the cellular structures and the underlying physiological and biochemical changes, we have constructed an experimental platform capable of delivering compression waves, of amplitudes relevant to blast, to cell suspensions in a contained environment. Initial characterization of the system shows that cell cultures can be subjected to high-intensity compression waves up to 15 MPa in pressure and duration of 80 ± 10μs. Studies of mouse mesenchymal stem cells subjected to two different pressure impulses were analysed by cell counting, cell viability assays and microscopic evaluation: the experiments present evidence suggestive of increased levels of damage and loss of cellular integrity compared to uncompressed cell cultures.

Blast induced mild traumatic brain injury/concussion: A physical analysis

NASA Astrophysics Data System (ADS)

Kucherov, Yan; Hubler, Graham K.; DePalma, Ralph G.

2012-11-01

Currently, a consensus exists that low intensity non-impact blast wave exposure leads to mild traumatic brain injury (mTBI). Considerable interest in this "invisible injury" has developed in the past few years but a disconnect remains between the biomedical outcomes and possible physical mechanisms causing mTBI. Here, we show that a shock wave travelling through the brain excites a phonon continuum that decays into specific acoustic waves with intensity exceeding brain tissue strength. Damage may occur within the period of the phonon wave, measured in tens to hundreds of nanometers, which makes the damage difficult to detect using conventional modalities.

Simulation and Measurements of Small Arms Blast Wave Overpressure in the Process of Designing a Silencer

NASA Astrophysics Data System (ADS)

Hristov, Nebojša; Kari, Aleksandar; Jerković, Damir; Savić, Slobodan; Sirovatka, Radoslav

2015-02-01

Simulation and measurements of muzzle blast overpressure and its physical manifestations are studied in this paper. The use of a silencer can have a great influence on the overpressure intensity. A silencer is regarded as an acoustic transducer and a waveguide. Wave equations for an acoustic dotted source of directed effect are used for physical interpretation of overpressure as an acoustic phenomenon. Decomposition approach has proven to be suitable to describe the formation of the output wave of the wave transducer. Electroacoustic analogies are used for simulations. A measurement chain was used to compare the simulation results with the experimental ones.

On meteor-generated infrasound. [propagation characteristics during entry into earth atmosphere

NASA Technical Reports Server (NTRS)

Revelle, D. O.

1976-01-01

The characteristics of generation and propagation of infrasonic pressure waves excited during meteor entry into the earth's atmosphere are studied. Existing line source blast wave theory is applied to infrasonic airwave data from four bright fire-balls. It is shown that the strong shock behavior of the blast wave is confined to a cylinderical region with a radius proportional to the product of the meteor Mach number and its diameter. A description of the wave form far from the source is provided. Infrasonic data reported elsewhere are analyzed. All the results should be considered as preliminary, and additional work is under way to refine the estimates obtained.

Intracranial pressure increases during exposure to a shock wave.

PubMed

Leonardi, Alessandra Dal Cengio; Bir, Cynthia A; Ritzel, Dave V; VandeVord, Pamela J

2011-01-01

Traumatic brain injuries (TBI) caused by improvised explosive devices (IEDs) affect a significant percentage of surviving soldiers wounded in Iraq and Afghanistan. The extent of a blast TBI, especially initially, is difficult to diagnose, as internal injuries are frequently unrecognized and therefore underestimated, yet problems develop over time. Therefore it is paramount to resolve the physical mechanisms by which critical stresses are inflicted on brain tissue from blast wave encounters with the head. This study recorded direct pressure within the brains of male Sprague-Dawley rats during exposure to blast. The goal was to understand pressure wave dynamics through the brain. In addition, we optimized in vivo methods to ensure accurate measurement of intracranial pressure (ICP). Our results demonstrate that proper sealing techniques lead to a significant increase in ICP values, compared to the outside overpressure generated by the blast. Further, the values seem to have a direct relation to a rat's size and age: heavier, older rats had the highest ICP readings. These findings suggest that a global flexure of the skull by the transient shockwave is an important mechanism of pressure transmission inside the brain.

Cerebellar White Matter Abnormalities following Primary Blast Injury in US Military Personnel

PubMed Central

Mac Donald, Christine; Johnson, Ann; Cooper, Dana; Malone, Thomas; Sorrell, James; Shimony, Joshua; Parsons, Matthew; Snyder, Abraham; Raichle, Marcus; Fang, Raymond; Flaherty, Stephen; Russell, Michael; Brody, David L.

2013-01-01

Little is known about the effects of blast exposure on the human brain in the absence of head impact. Clinical reports, experimental animal studies, and computational modeling of blast exposure have suggested effects on the cerebellum and brainstem. In US military personnel with isolated, primary blast-related ‘mild’ traumatic brain injury and no other known insult, we found diffusion tensor MRI abnormalities consistent with cerebellar white matter injury in 3 of 4 subjects. No abnormalities in other brain regions were detected. These findings add to the evidence supporting the hypothesis that primary blast exposure contributes to brain injury in the absence of head impact and that the cerebellum may be particularly vulnerable. However, the clinical effects of these abnormalities cannot be determined with certainty; none of the subjects had ataxia or other detected evidence of cerebellar dysfunction. The details of the blast events themselves cannot be disclosed at this time, thus additional animal and computational modeling will be required to dissect the mechanisms underlying primary blast-related traumatic brain injury. Furthermore, the effects of possible subconcussive impacts and other military-related exposures cannot be determined from the data presented. Thus many aspects of topic will require further investigation. PMID:23409052

Survey of seismic conditions of drilling and blasting operations near overhead electricity power lines

NASA Astrophysics Data System (ADS)

Korshunov, G. I.; Afanasev, P. I.; Bulbasheva, I. A.

2017-10-01

The monitoring and survey results of drilling and blasting operations are specified during the development of Afanasyevsky deposit of cement raw materials for a 110 kV electricity power lines structure. Seismic explosion waves and air shock waves were registered in the course of monitoring. The dependency of peak particle velocities on the scaled distance and explosive weight by the delay time was obtained.

Calculation of wing response to gusts and blast waves with vortex lift effect

NASA Technical Reports Server (NTRS)

Chao, D. C.; Lan, C. E.

1983-01-01

A numerical study of the response of aircraft wings to atmospheric gusts and to nuclear explosions when flying at subsonic speeds is presented. The method is based upon unsteady quasi-vortex lattice method, unsteady suction analogy and Pade approximant. The calculated results, showing vortex lag effect, yield reasonable agreement with experimental data for incremental lift on wings in gust penetration and due to nuclear blast waves.

Nonuniform Expansion of the Youngest Galactic Supernova Remnant G1.9+0.3

NASA Technical Reports Server (NTRS)

Borkowski, Kazimierz J.; Reynolds, Stephen P.; Green, David A.; Hwang, Una; Petre, Robert; Krishnamurthy, Kalyani; Willett, Rebecca

2014-01-01

We report measurements of the X-ray expansion of the youngest Galactic supernova remnant, G1.9+0.3, using Chandra observations in 2007, 2009, and 2011. The measured rates strongly deviate from uniform expansion, decreasing radially by about 60 along the X-ray bright SE-NW axis from 0.84 plus or minus 0.06% yr(exp -1) to 0.52% plus or minus 0.03 yr(exp -1). This corresponds to undecelerated ages of 120-190 yr, confirming the young age of G1.9+0.3 and implying a significant deceleration of the blast wave. The synchrotron-dominated X-ray emission brightens at a rate of 1.9% plus or minus 0.4% yr(exp -1). We identify bright outer and inner rims with the blast wave and reverse shock, respectively. Sharp density gradients in either the ejecta or ambient medium are required to produce the sudden deceleration of the reverse shock or the blast wave implied by the large spread in expansion ages. The blast wave could have been decelerated recently by an encounter with a modest density discontinuity in the ambient medium, such as may be found at a wind termination shock, requiring strong mass loss in the progenitor.

NO FLARES FROM GAMMA-RAY BURST AFTERGLOW BLAST WAVES ENCOUNTERING SUDDEN CIRCUMBURST DENSITY CHANGE

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gat, Ilana; Van Eerten, Hendrik; MacFadyen, Andrew

2013-08-10

Afterglows of gamma-ray bursts are observed to produce light curves with the flux following power-law evolution in time. However, recent observations reveal bright flares at times on the order of minutes to days. One proposed explanation for these flares is the interaction of a relativistic blast wave with a circumburst density transition. In this paper, we model this type of interaction computationally in one and two dimensions, using a relativistic hydrodynamics code with adaptive mesh refinement called RAM, and analytically in one dimension. We simulate a blast wave traveling in a stellar wind environment that encounters a sudden change inmore » density, followed by a homogeneous medium, and compute the observed radiation using a synchrotron model. We show that flares are not observable for an encounter with a sudden density increase, such as a wind termination shock, nor for an encounter with a sudden density decrease. Furthermore, by extending our analysis to two dimensions, we are able to resolve the spreading, collimation, and edge effects of the blast wave as it encounters the change in circumburst medium. In all cases considered in this paper, we find that a flare will not be observed for any of the density changes studied.« less

High-speed imaging and small-scale explosive characterization techniques to understand effects of primary blast-induced injury on nerve cell structure and function

NASA Astrophysics Data System (ADS)

Piehler, T.; Banton, R.; Zander, N.; Duckworth, J.; Benjamin, R.; Sparks, R.

2018-01-01

Traumatic brain injury (TBI) is often associated with blast exposure. Even in the absence of penetrating injury or evidence of tissue injury on imaging, blast TBI may trigger a series of neural/glial cellular and functional changes. Unfortunately, the diagnosis and proper treatment of mild traumatic brain injury (mTBI) caused by explosive blast is challenging, as it is not easy to clinically distinguish blast from non-blast TBI on the basis of patient symptoms. Damage to brain tissue, cell, and subcellular structures continues to occur slowly and in a manner undetectable by conventional imaging techniques. The threshold shock impulse levels required to induce damage and the cumulative effects upon multiple exposures are not well characterized. Understanding how functional and structural damage from realistic blast impact at cellular and tissue levels at variable timescales after mTBI events may be vital for understanding this injury phenomenon and for linking mechanically induced structural changes with measurable effects on the nervous system. Our working hypothesis is that there is some transient physiological dysfunction occurring at cellular and subcellular levels within the central nervous system due to primary blast exposure. We have developed a novel in vitro indoor experimental system that uses real military explosive charges to more accurately represent military blast exposure and to probe the effects of primary explosive blast on dissociated neurons. We believe this system offers a controlled experimental method to analyze and characterize primary explosive blast-induced cellular injury and to understand threshold injury phenomenon. This paper will also focus on the modeling aspect of our work and how it relates to the experimental work.

Particle momentum effects from the detonation of heterogeneous explosives

NASA Astrophysics Data System (ADS)

Frost, D. L.; Ornthanalai, C.; Zarei, Z.; Tanguay, V.; Zhang, F.

2007-06-01

Detonation of a spherical high explosive charge containing solid particles generates a high-speed two-phase flow comprised of a decaying spherical air blast wave together with a rapidly expanding cloud of particles. The particle momentum effects associated with this two-phase flow have been investigated experimentally and numerically for a heterogeneous explosive consisting of a packed bed of inert particles saturated with a liquid explosive. Experimentally, the dispersion of the particles was tracked using flash radiography and high-speed photography. A particle streak gauge was developed to measure the rate of arrival of the particles at various locations. Using a cantilever gauge and a free-piston impulse gauge, it was found that the particle momentum flux provided the primary contribution of the multiphase flow to the near-field impulse applied to a nearby small structure. The qualitative features of the interaction between a particle and the flow field are illustrated using simple models for the particle motion and blast wave dynamics. A more realistic Eulerian two-fluid model for the gas-particle flow and a finite-element model for the structural response of the cantilever gauge are then used to determine the relative contributions of the gas and particles to the loading.

Computational modeling of blast wave interaction with a human body and assessment of traumatic brain injury

NASA Astrophysics Data System (ADS)

Tan, X. G.; Przekwas, A. J.; Gupta, R. K.

2017-11-01

The modeling of human body biomechanics resulting from blast exposure poses great challenges because of the complex geometry and the substantial material heterogeneity. We developed a detailed human body finite element model representing both the geometry and the materials realistically. The model includes the detailed head (face, skull, brain and spinal cord), the neck, the skeleton, air cavities (lungs) and the tissues. Hence, it can be used to properly model the stress wave propagation in the human body subjected to blast loading. The blast loading on the human was generated from a simulated C4 explosion. We used the highly scalable solvers in the multi-physics code CoBi for both the blast simulation and the human body biomechanics. The meshes generated for these simulations are of good quality so that relatively large time-step sizes can be used without resorting to artificial time scaling treatments. The coupled gas dynamics and biomechanics solutions were validated against the shock tube test data. The human body models were used to conduct parametric simulations to find the biomechanical response and the brain injury mechanism due to blasts impacting the human body. Under the same blast loading condition, we showed the importance of inclusion of the whole body.

Shock tubes and waves; Proceedings of the Sixteenth International Symposium, Rheinisch-Westfaelische Technische Hochschule, Aachen, Federal Republic of Germany, July 26-31, 1987

NASA Astrophysics Data System (ADS)

Groenig, Hans

Topics discussed in this volume include shock wave structure, propagation, and interaction; shocks in condensed matter, dusty gases, and multiphase media; chemical processes and related combustion and detonation phenomena; shock wave reflection, diffraction, and focusing; computational fluid dynamic code development and shock wave application; blast and detonation waves; advanced shock tube technology and measuring technique; and shock wave applications. Papers are presented on dust explosions, the dynamics of shock waves in certain dense gases, studies of condensation kinetics behind incident shock waves, the autoignition mechanism of n-butane behind a reflected shock wave, and a numerical simulation of the focusing process of reflected shock waves. Attention is also given to the equilibrium shock tube flow of real gases, blast waves generated by planar detonations, modern diagnostic methods for high-speed flows, and interaction between induced waves and electric discharge in a very high repetition rate excimer laser.

Modelling and Experimental Verification of Pressure Wave Following Gaseous Helium Storage Tank Rupture

NASA Astrophysics Data System (ADS)

Chorowski, M.; Grabowski, M.; Jędrusyna, A.; Wach, J.

Helium inventory in high energy accelerators, tokamaks and free electron lasers may exceed tens of tons. The gaseous helium is stored in steel tanks under a pressure of about 20 bar and at environment temperature. Accidental rupture of any of the tanks filled with the gaseous helium will create a rapid energy release in form of physical blast. An estimation of pressure wave distribution following the tank rupture and potential consequences to the adjacent research infrastructure and buildings is a very important task, critical in the safety aspect of the whole cryogenic system. According to the present regulations the TNT equivalent approach is to be applied to evaluate the pressure wave following a potential gas storage tank rupture. A special test stand was designed and built in order to verify experimentally the blast effects in controlled conditions. In order to obtain such a shock wave a pressurized plastic tank was used. The tank was ruptured and the resulting pressure wave was recorded using a spatially-distributed array of pressure sensors connected to a high-speed data acquisition device. The results of the experiments and the comparison with theoretical values obtained from thermodynamic model of the blast are presented. A good agreement between the simulated and measured data was obtained. Recommendations regarding the applicability of thermodynamic model of physical blast versus TNT approach, to estimate consequences of gas storage tank rupture are formulated. The laboratory scale experimental results have been scaled to ITER pressurized helium storage tanks.

Effects of Filtering on Experimental Blast Overpressure Measurements.

PubMed

Alphonse, Vanessa D; Kemper, Andrew R; Duma, Stefan M

2015-01-01

When access to live-fire test facilities is limited, experimental studies of blast-related injuries necessitate the use of a shock tube or Advanced Blast Simulator (ABS) to mimic free-field blast overpressure. However, modeling blast overpressure in a laboratory setting potentially introduces experimental artifacts in measured responses. Due to the high sampling rates required to capture a blast overpressure event, proximity to alternating current (AC-powered electronics) and poorly strain-relieved or unshielded wires can result in artifacts in the recorded overpressure trace. Data in this study were collected for tests conducted on an empty ABS (“Empty Tube”) using high frequency pressure sensors specifically designed for blast loading rates (n=5). Additionally, intraocular overpressure data (“IOP”) were collected for porcine eyes potted inside synthetic orbits located inside the ABS using an unshielded miniature pressure sensor (n=3). All tests were conducted at a 30 psi static overpressure level. A 4th order phaseless low pass Butterworth software filter was applied to the data. Various cutoff frequencies were examined to determine if the raw shock wave parameters values could be preserved while eliminating noise and artifacts. A Fast Fourier Transform (FFT) was applied to each test to examine the frequency spectra of the raw and filtered signals. Shock wave parameters (time of arrival, peak overpressure, positive duration, and positive impulse) were quantified using a custom MATLAB® script. Lower cutoff frequencies attenuated the raw signal, effectively decreasing the peak overpressure and increasing the positive duration. Rise time was not preserved the filtered data. A CFC 6000 filter preserved the remaining shock wave parameters within ±2.5% of the average raw values for the Empty Tube test data. A CFC 7000 filter removed experimental high-frequency artifacts and preserved the remaining shock wave parameters within ±2.5% of the average raw values for test IOP test data. Though the region of interest of the signals examined in the current study did not contain extremely high frequency content, it is possible that live-fire testing may produce shock waves with higher frequency content. While post-processing filtering can remove experimental artifacts, special care should be taken to minimize or eliminate the possibility of recording these artifacts in the first place.

Distributed Mobile Device Based Shooter Detection Simulation

DTIC Science & Technology

2013-09-01

three signatures of a gunshot ( muzzle flash [optical], muzzle blast [auditory], and shock wave [auditory]), we focus only on information from the...bullet, while this proximity is important when using information from the shock wave. Detecting and using the muzzle flash would require accurate...Additionally, the mobile device would need to be aimed towards the blast to even have a chance detect the muzzle flash . 2.1 Single Microphone When a sound is

Non-Impact, Blast-Induced Mild TBI and PTSD: Concepts and Caveats

DTIC Science & Technology

2011-07-01

has been verified by wound ballistics experiments in animals and finite element simulation of blast loads on the torso. Blood surge caused by...ballistic pressure waves in animals An experimental study of wound ballistics demon- strates that a ballistic pressure wave can cause a remote injury to...surge. This hypothesis has been supported by some experimental data. A volumetric surge of blood moved through the thorax and abdomen has been observed

Simulation of the Reflected Blast Wave froma C-4 Charge

DOE Office of Scientific and Technical Information (OSTI.GOV)

Howard, W M; Kuhl, A L; Tringe, J W

2011-08-01

The reflection of a blast wave from a C4 charge detonated above a planar surface is simulated with our ALE3D code. We used a finely-resolved, fixed Eulerian 2-D mesh (167 {micro}m per cell) to capture the detonation of the charge, the blast wave propagation in nitrogen, and its reflection from the surface. The thermodynamic properties of the detonation products and nitrogen were specified by the Cheetah code. A programmed-burn model was used to detonate the charge at a rate based on measured detonation velocities. Computed pressure histories are compared with pressures measured by Kistler 603B piezoelectric gauges at 8 rangesmore » (GR = 0, 2, 4, 8, 10, and 12 inches) along the reflecting surface. Computed and measured waveforms and positive-phase impulses were similar, except at close-in ranges (GR < 2 inches), which were dominated by jetting effects.« less

Simulation of the reflected blast wave from a C-4 charge

NASA Astrophysics Data System (ADS)

Howard, W. Michael; Kuhl, Allen L.; Tringe, Joseph

2012-03-01

The reflection of a blast wave from a C4 charge detonated above a planar surface is simulated with our ALE3D code. We used a finely-resolved, fixed Eulerian 2-D mesh (167 μm per cell) to capture the detonation of the charge, the blast wave propagation in nitrogen, and its reflection from the surface. The thermodynamic properties of the detonation products and nitrogen were specified by the Cheetah code. A programmed-burn model was used to detonate the charge at a rate based on measured detonation velocities. Computed pressure histories are compared with pressures measured by Kistler 603B piezoelectric gauges at 7 ranges (GR = 0, 5.08, 10.16, 15.24, 20.32, 25.4, and 30.48 cm) along the reflecting surface. Computed and measured waveforms and positive-phase impulses were similar, except at close-in ranges (GR < 5 cm), which were dominated by jetting effects.

Cloth ballistic vest alters response to blast.

PubMed

Phillips, Y Y; Mundie, T G; Yelverton, J T; Richmond, D R

1988-01-01

Ballistic wounds have been and will remain the principal cause of casualties in combat. Cloth ballistic vests (CBV) play an important role in limiting critical wounds from fragments and small-arms fire. There is an increased risk of primary blast injury on the modern battlefield. In a previous study, volunteers were exposed to short-duration blast waves of low peak pressure (18.6 +/- 0.8 kPa). Pressure measurements made in the distal esophagus as an estimate of intrathoracic pressure (ITP) were significantly higher (p less than 0.05) when the standard U.S. Army ballistic jacket was worn (8.7 +/- 1.2 kPa) than when fatigues alone were worn (7.4 +/- 0.7 kPa). In this study 58 sheep were exposed to nominal blast levels of 115, 230, 295, and 420 kPa peak pressure in groups of 12, 18, 16, and 12, respectively. Half of each group was fitted with a CBV. Lung weight index (LWI), lung weight expressed as a percentage of body weight, was used as a measure of blast injury. Use of the CBV was associated with a significant increase in LWI (p less than 0.05) which averaged 21% for the two middle exposure groups. At the 420 kPa level, two of six non-CBV animals died as opposed to five of six animals wearing the CBV. Intrathoracic pressure was generally higher in the CBV group. Likely mechanisms of injury enhancement include an increase in target surface area and an alteration of the effective loading function on the thorax. This information may be useful in the triage and treatment of casualties exposed to intense blast environments.

Air blasts generated by rockfall impacts: Analysis of the 1996 Happy Isles event in Yosemite National Park

USGS Publications Warehouse

Morrissey, M.M.; Savage, W.Z.; Wieczorek, G.F.

1999-01-01

The July 10, 1996, Happy Isles rockfall in Yosemite National Park, California, released 23,000 to 38,000 m3 of granite in four separate events. The impacts of the first two events which involved a 550-m free fall, generated seismic waves and atmospheric pressure waves (air blasts). We focus on the dynamic behavior of the second air blast that downed over 1000 trees, destroyed a bridge, demolished a snack bar, and caused one fatality and several injuries. Calculated velocities for the air blast from a two-phase, finite difference model are compared to velocities estimated from tree damage. From tornadic studies of tree damage, the air blast is estimated to have traveled <108-120 m/s within 50 m from the impact and decreased to <10-20 m/s within 500 m from the impact. The numerical model simulates the two-dimensional propagation of an air blast through a dusty atmosphere with initial conditions defined by the impact velocity and pressure. The impact velocity (105-107 m/s) is estimated from the Colorado Rockfall Simulation Program that simulates rockfall trajectories. The impact pressure (0.5 MPa) is constrained by the kinetic energy of the impact (1010-1012 J) estimated from the seismic energy generated by the impact. Results from the air blast simulations indicate that the second Happy Isles air blast (weak shock wave) traveled with an initial velocity above the local sound speed. The size and location of the first impact are thought to have injected <50 wt % dust into the atmosphere. This amount of dust lowered the local atmospheric sound speed to ???220 m/s. The discrepancy between calculated velocity data and field estimated velocity data (???220 m/s versus ???110 m/s) is attributed to energy dissipated by the downing of trees and additional entrainment of debris into the atmosphere not included in the calculations. Copyright 1999 by the American Geophysical Union.

Air blasts generated by rockfall impacts: Analysis of the 1996 Happy Isles event in Yosemite National Park

NASA Astrophysics Data System (ADS)

Morrissey, M. M.; Savage, W. Z.; Wieczorek, G. F.

1999-10-01

The July 10, 1996, Happy Isles rockfall in Yosemite National Park, California, released 23,000 to 38,000 m3 of granite in four separate events. The impacts of the first two events which involved a 550-m free fall, generated seismic waves and atmospheric pressure waves (air blasts). We focus on the dynamic behavior of the second air blast that downed over 1000 trees, destroyed a bridge, demolished a snack bar, and caused one fatality and several injuries. Calculated velocities for the air blast from a two-phase, finite difference model are compared to velocities estimated from tree damage. From tornadic studies of tree damage, the air blast is estimated to have traveled <108-120 m/s within 50 m from the impact and decreased to <10-20 m/s within 500 m from the impact. The numerical model simulates the two-dimensional propagation of an air blast through a dusty atmosphere with initial conditions defined by the impact velocity and pressure. The impact velocity (105-107 m/s) is estimated from the Colorado Rockfall Simulation Program that simulates rockfall trajectories. The impact pressure (0.5 MPa) is constrained by the kinetic energy of the impact (1010-1012 J) estimated from the seismic energy generated by the impact. Results from the air blast simulations indicate that the second Happy Isles air blast (weak shock wave) traveled with an initial velocity above the local sound speed. The size and location of the first impact are thought to have injected <50 wt% dust into the atmosphere. This amount of dust lowered the local atmospheric sound speed to ˜220 m/s. The discrepancy between calculated velocity data and field estimated velocity data (˜220 m/s versus ˜110 m/s) is attributed to energy dissipated by the downing of trees and additional entrainment of debris into the atmosphere not included in the calculations.

High-fidelity simulations of blast loadings in urban environments using an overset meshing strategy

NASA Astrophysics Data System (ADS)

Wang, X.; Remotigue, M.; Arnoldus, Q.; Janus, M.; Luke, E.; Thompson, D.; Weed, R.; Bessette, G.

2017-05-01

Detailed blast propagation and evolution through multiple structures representing an urban environment were simulated using the code Loci/BLAST, which employs an overset meshing strategy. The use of overset meshes simplifies mesh generation by allowing meshes for individual component geometries to be generated independently. Detailed blast propagation and evolution through multiple structures, wave reflection and interaction between structures, and blast loadings on structures were simulated and analyzed. Predicted results showed good agreement with experimental data generated by the US Army Engineer Research and Development Center. Loci/BLAST results were also found to compare favorably to simulations obtained using the Second-Order Hydrodynamic Automatic Mesh Refinement Code (SHAMRC). The results obtained demonstrated that blast reflections in an urban setting significantly increased the blast loads on adjacent buildings. Correlations of computational results with experimental data yielded valuable insights into the physics of blast propagation, reflection, and interaction under an urban setting and verified the use of Loci/BLAST as a viable tool for urban blast analysis.

The multi-modal responses of a physical head model subjected to various blast exposure conditions

NASA Astrophysics Data System (ADS)

Ouellet, S.; Philippens, M.

2018-01-01

The local and global biomechanical response of the body to a blast wave is the first step of a sequence that leads to the development of stresses and strains which can exceed the tolerance of brain tissue. These stresses and strains may then lead to neuro-physical changes in the brain and contribute to initiate a cascade of events leading to injury. The specific biomechanical pathways by which the blast energy is transmitted through the head structure are, however, not clearly understood. Multiple transmission mechanisms have been proposed to explain the generation of brain stresses following the impingement of a blast wave on the head. With the use of a physical head model, the work presented here aims at demonstrating that the proposed transmission mechanisms are not mutually exclusive. They are part of a continuum of head responses where, depending on the exposure conditions, a given mechanism may or may not dominate. This article presents the joint analysis of previous blast test results generated with the brain injury protection evaluation device (BIPED) headform under four significantly different exposure conditions. The focus of the analysis is to demonstrate how the nature of the recorded response is highly dependent on the exposure characteristics and consequently, on the method used to reproduce blast exposure in a laboratory environment. The timing and magnitude of the variations in intra-cranial pressures (ICP) were analysed relative to the external pressure field in order to better understand the wave dynamics occurring within the brain structure of the headform. ICP waveforms were also analysed in terms of their energy spectral density to better identify the energy partitioning between the different modes of response. It is shown that the BIPED response is multi-modal and that the energy partitioning between its different modes of response is greatly influenced by exposure characteristics such as external peak overpressure, impulse, blast wave structure, and direction of propagation. Convincing evidence of stresses generated from local skull deformation is presented along with evidence of stress transmission through relative brain-to-skull motion. These findings suggest that research aimed at defining exposure thresholds should not focus on a single stress transmission mechanism or use experimental designs unrepresentative of realistic blast loading conditions that may favour a given mechanism over another.

Integrated experimental platforms to study blast injuries: a bottom-up approach

NASA Astrophysics Data System (ADS)

Bo, C.; Williams, A.; Rankin, S.; Proud, W. G.; Brown, K. A.

2014-05-01

We are developing experimental models of blast injury using data from live biological samples. An integrated research strategy is followed to study material and biological properties of cells, tissues and organs, that are subjected to dynamic and static pressures, relevant to those of battlefield blast. We have developed a confined Split Hopkinson Pressure Bar (SHPB) system, which allows cells, either in suspension or as a monolayer, to be subjected to compression waves with pressures on the order of a few MPa and durations of hundreds of microseconds. The chamber design enables recovery of biological samples for cellular and molecular analysis. The SHPB platform, coupled with Quasi-Static experiments, is used to determine stress-strain curves of soft biological tissues under compression at low, medium and high strain rates. Tissue samples are examined, using histological techniques, to study macro- and microscopic changes induced by compression waves. In addition, a shock tube enables application of single or multiple air blasts with pressures on the order of kPa and a few milliseconds duration; this platform was used for initial studies on mesenchymal stem cells responses to blast pressures.

Elucidation of Inflammation Processes Exacerbating Neuronal Cell Damage to the Retina and Brain Visual Centers as Quest for Therapeutic Drug Targets in Rat Model of Blast Overpressure Wave Exposure

DTIC Science & Technology

tissues, as carried out by immune cells; and thus is a promising target. Scope and timing, however, of this process must be better understood. Our study...uses an adult rat model of eye and brain injuries, as produced by exposure to simulated blast waves in a shock tube. Rats were kept on an omega-3

The effect of cosmic-ray acceleration on supernova blast wave dynamics

NASA Astrophysics Data System (ADS)

Pais, M.; Pfrommer, C.; Ehlert, K.; Pakmor, R.

2018-05-01

Non-relativistic shocks accelerate ions to highly relativistic energies provided that the orientation of the magnetic field is closely aligned with the shock normal (quasi-parallel shock configuration). In contrast, quasi-perpendicular shocks do not efficiently accelerate ions. We model this obliquity-dependent acceleration process in a spherically expanding blast wave setup with the moving-mesh code AREPO for different magnetic field morphologies, ranging from homogeneous to turbulent configurations. A Sedov-Taylor explosion in a homogeneous magnetic field generates an oblate ellipsoidal shock surface due to the slower propagating blast wave in the direction of the magnetic field. This is because of the efficient cosmic ray (CR) production in the quasi-parallel polar cap regions, which softens the equation of state and increases the compressibility of the post-shock gas. We find that the solution remains self-similar because the ellipticity of the propagating blast wave stays constant in time. This enables us to derive an effective ratio of specific heats for a composite of thermal gas and CRs as a function of the maximum acceleration efficiency. We finally discuss the behavior of supernova remnants expanding into a turbulent magnetic field with varying coherence lengths. For a maximum CR acceleration efficiency of about 15 per cent at quasi-parallel shocks (as suggested by kinetic plasma simulations), we find an average efficiency of about 5 per cent, independent of the assumed magnetic coherence length.

Temporal and Spatial Effects of Blast Overpressure on Blood-Brain Barrier Permeability in Traumatic Brain Injury.

PubMed

Kuriakose, Matthew; Rama Rao, Kakulavarapu V; Younger, Daniel; Chandra, Namas

2018-06-06

Blast-induced traumatic brain injury (bTBI) is a "signature wound" in soldiers during training and in combat and has also become a major cause of morbidity in civilians due to increased insurgency. This work examines the role of blood-brain barrier (BBB) disruption as a result of both primary biomechanical and secondary biochemical injury mechanisms in bTBI. Extravasation of sodium fluorescein (NaF) and Evans blue (EB) tracers were used to demonstrate that compromise of the BBB occurs immediately following shock loading, increases in intensity up to 4 hours and returns back to normal in 24 hours. This BBB compromise occurs in multiple regions of the brain in the anterior-posterior direction of the shock wave, with maximum extravasation seen in the frontal cortex. Compromise of the BBB is confirmed by (a) extravasation of tracers into the brain, (b) quantification of tight-junction proteins (TJPs) in the brain and the blood, and (c) tracking specific blood-borne molecules into the brain and brain-specific proteins into the blood. Taken together, this work demonstrates that the BBB compromise occurs as a part of initial biomechanical loading and is a function of increasing blast overpressures.

An ultra-fast fiber optic pressure sensor for blast event measurements

NASA Astrophysics Data System (ADS)

Wu, Nan; Zou, Xiaotian; Tian, Ye; Fitek, John; Maffeo, Michael; Niezrecki, Christopher; Chen, Julie; Wang, Xingwei

2012-05-01

Soldiers who are exposed to explosions are at risk of suffering traumatic brain injury (TBI). Since the causal relationship between a blast and TBI is poorly understood, it is critical to have sensors that can accurately quantify the blast dynamics and resulting wave propagation through a helmet and skull that are imparted onto and inside the brain. To help quantify the cause of TBI, it is important to record transient pressure data during a blast event. However, very few sensors feature the capabilities of tracking the dynamic pressure transients due to the rapid change of the pressure during blast events, while not interfering with the physical material layers or wave propagation. In order to measure the pressure transients efficiently, a pressure sensor should have a high resonant frequency and a high spatial resolution. This paper describes an ultra-fast fiber optic pressure sensor based on the Fabry-Perot principle for the application of measuring the rapid pressure changes in a blast event. A shock tube experiment performed in US Army Natick Soldier Research, Development and Engineering Center has demonstrated that the resonant frequency of the sensor is 4.12 MHz, which is relatively close to the designed theoretical value of 4.113 MHz. Moreover, the experiment illustrated that the sensor has a rise time of 120 ns, which demonstrates that the sensor is capable of observing the dynamics of the pressure transient during a blast event.

Surface wave inversion of central Texas quarry blasts

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bonner, J.L.; Goforth, T.T.

1993-02-01

Compressional and shear wave models of the upper crust in central Texas were obtained by inverting Rayleigh and Love waves recorded at the new W.M. Keck Foundation Seismological Observatory at Baylor University. The Keck Observatory, which became operational in April 1992, consists of a three-component, broadband Geotech seismometer located at a depth of 130 feet in a borehole 17 miles from the Baylor campus. The field station is solar powered, and the 140-dB dynamic range digital data are transmitted to the Baylor analysis lab via radio, where they are analyzed and archived. Limestone quarries located in all directions from themore » Keck Observatory detonate two to four tons of explosives per blast several times a week. Recordings of these blasts show sharp onsets of P and S waves, as well as dispersed Rayleigh and Love waves in the period band 1 to 3 seconds. Multiple filter analysis and phase matched filtering techniques were used to obtain high quality dispersion curves for the surface waves, and inversion techniques were applied to produce shear velocity models of the upper crust. A rapid increase in shear velocity at a depth of about 1.5 km is associated with the Ouachita Overthrust Belt. Portable seismic recording systems were placed at the quarries to monitor start times and initial wave forms. These data were combined with the Keck recordings to produce attenuation and compressional velocity models.« less

Efficacy of visor and helmet for blast protection assessed using a computational head model

NASA Astrophysics Data System (ADS)

Singh, D.; Cronin, D. S.

2017-11-01

Head injury resulting from blast exposure has been identified as a challenge that may be addressed, in part, through improved protective systems. Existing detailed head models validated for blast loading were applied to investigate the influence of helmet visor configuration, liner properties, and shell material stiffness. Response metrics including head acceleration and intracranial pressures (ICPs) generated in brain tissue during primary blast exposure were used to assess and compare helmet configurations. The addition of a visor was found to reduce peak head acceleration and positive ICPs. However, negative ICPs associated with a potential for injury were increased when a visor and a foam liner were present. In general, the foam liner material was found to be more significant in affecting the negative ICP response than positive ICP or acceleration. Shell stiffness was found to have relatively small effects on either metric. A strap suspension system, modeled as an air gap between the head and helmet, was more effective in reducing response metrics compared to a foam liner. In cases with a foam liner, lower-density foam offered a greater reduction of negative ICPs. The models demonstrated the "underwash" effect in cases where no foam liner was present; however, the reflected pressures generated between the helmet and head did not translate to significant ICPs in adjacent tissue, when compared to peak ICPs from initial blast wave interaction. This study demonstrated that the efficacy of head protection can be expressed in terms of load transmission pathways when assessed with a detailed computational model.

Characteristics and mechanisms of cardiopulmonary injury caused by mine blasts in shoals: a randomized controlled study in a rabbit model.

PubMed

Han, Gengfen; Wang, Ziming; Wang, Jianmin; Yang, Weixiao; Chen, Jing; Kang, Jianyi; Zhang, Sen; Wang, Aimin; Lai, Xinan

2013-01-01

Because the characteristics of blast waves in water are different from those in air and because kinetic energy is liberated by a pressure wave at the water-air interface, thoracic injuries from mine blasts in shoals may be serious. The aim of the present study was to investigate the characteristics and mechanisms of cardiopulmonary injury caused by mine blasts in shoals. To study the characteristics of cardiopulmonary injury, 56 animals were divided randomly into three experimental groups (12 animals in the sham group, 22 animals in the land group and 22 animals in the shoal group). To examine the biomechanics of injury, 20 animals were divided randomly into the land group and the shoal group. In the experimental model, the water surface was at the level of the rabbit's xiphoid process, and paper electric detonators (600 mg RDX) were used to simulate mines. Electrocardiography and echocardiography were conducted, and arterial blood gases, serum levels of cardiac troponin I and creatine kinase-MB and other physiologic parameters were measured over a 12-hour period after detonation. Pressures in the thorax and abdomen and the acceleration of the thorax were measured. The results indicate that severe cardiopulmonary injury and dysfunction occur following exposure to mine blasts in shoals. Therefore, the mechanisms of cardiopulmonary injury may result from shear waves that produce strain at the water-air interface. Another mechanism of injury includes the propagation of the shock wave from the planta to the thorax, which causes a much higher peak overpressure in the abdomen than in the thorax; as a result, the abdominal organs and diaphragm are thrust into the thorax, damaging the lungs and heart.

Characterization and Modeling of Thoraco-Abdominal Response to Blast Waves. Volume 4. Biomechanical Model of Thorax Response to Blast Loading

DTIC Science & Technology

1985-05-01

non- zero Dirichlet boundary conditions and/or general mixed type boundary conditions. Note that Neumann type boundary condi- tion enters the problem by...Background ................................. ................... I 1.3 General Description ..... ............ ........... . ....... ...... 2 2. ANATOMICAL...human and varions loading conditions for the definition of a generalized safety guideline of blast exposure. To model the response of a sheep torso

Intrathoracic pressure variations in an anthropomorphic dummy exposed to air blast, blunt impact, and missiles.

PubMed

Jönsson, A; Arvebo, E; Schantz, B

1988-01-01

Experiments with an anthropomorphic dummy for blast research demonstrated that pressures recorded in the lung model of the dummy could be correlated to primary air blast effects on the lungs of experimental animals. The results presented here were obtained with a dummy of the type mentioned above, but with the lung model modified to improve geometric similarity to man. Blast experiments were performed in a shock tube, and impact experiments in a special impact machine. Experiments with nonpenetrating missiles were performed with small-caliber firearms and the dummy protected by body armor. Severity indices derived from the blast experiments were related to established criteria for primary lung injury in man. Impacts delivered in the impact machine and by nonpenetrating missiles are compared. Relationships between severity of impact based on experiments with animals and primary lung injury in man are discussed.

Interaction of Supernova Blast Waves with Wind-Driven Shells: Formation of "Jets", "Bullets", "Ears", Etc.

NASA Astrophysics Data System (ADS)

Gvaramadze, V. V.

Most of middle-aged supernova remnants (SNRs) have a distorted and complicated appearance which cannot be explained in the framework of the Sedov-Taylor model. We consider three typical examples of such SNRs (Vela SNR, MSH15-52, G309.2-00.6) and show that their structure could be explained as a result of interaction of a supernova (SN) blast wave with the ambient medium preprocessed by the action of the SN progenitor's wind and ionized emission.

Damage Detection of a Concrete Column Subject to Blast Loads Using Embedded Piezoceramic Transducers.

PubMed

Xu, Kai; Deng, Qingshan; Cai, Lujun; Ho, Siuchun; Song, Gangbing

2018-04-28

Some of the most severe structural loadings come in the form of blast loads, which may be caused by severe accidents or even terrorist activities. Most commonly after exposure to explosive forces, a structure will suffer from different degrees of damage, and even progress towards a state of collapse. Therefore, damage detection of a structure subject to explosive loads is of importance. This paper proposes a new approach to damage detection of a concrete column structure subjected to blast loads using embedded piezoceramic smart aggregates (SAs). Since the sensors are embedded in the structure, the proposed active-sensing based approach is more sensitive to internal or through cracks than surface damage. In the active sensing approach, the embedded SAs act as actuators and sensors, that can respectively generate and detect stress waves. If the stress wave propagates across a crack, the energy of the wave attenuates, and the reduction of the energy compared to the healthy baseline is indicative of a damage. With a damage index matrix constructed by signals obtained from an array of SAs, cracks caused by blast loads can be detected throughout the structure. Conventional sensing methods such as the measurement of dynamic strain and acceleration were included in the experiment. Since columns are critical elements needed to prevent structural collapse, knowledge of their integrity and damage conditions is essential for safety after exposure to blast loads. In this research, a concrete column with embedded SAs was chosen as the specimen, and a series of explosive tests were conducted on the column. Experimental results reveal that surface damages, though appear severe, cause minor changes in the damage index, and through cracks result in significant increase of the damage index, demonstrating the effectiveness of the active sensing, enabled by embedded SAs, in damage monitoring of the column under blast loads, and thus providing a reliable indication of structural integrity in the event of blast loads.

Damage Detection of a Concrete Column Subject to Blast Loads Using Embedded Piezoceramic Transducers

PubMed Central

Deng, Qingshan; Cai, Lujun; Ho, Siuchun; Song, Gangbing

2018-01-01

Some of the most severe structural loadings come in the form of blast loads, which may be caused by severe accidents or even terrorist activities. Most commonly after exposure to explosive forces, a structure will suffer from different degrees of damage, and even progress towards a state of collapse. Therefore, damage detection of a structure subject to explosive loads is of importance. This paper proposes a new approach to damage detection of a concrete column structure subjected to blast loads using embedded piezoceramic smart aggregates (SAs). Since the sensors are embedded in the structure, the proposed active-sensing based approach is more sensitive to internal or through cracks than surface damage. In the active sensing approach, the embedded SAs act as actuators and sensors, that can respectively generate and detect stress waves. If the stress wave propagates across a crack, the energy of the wave attenuates, and the reduction of the energy compared to the healthy baseline is indicative of a damage. With a damage index matrix constructed by signals obtained from an array of SAs, cracks caused by blast loads can be detected throughout the structure. Conventional sensing methods such as the measurement of dynamic strain and acceleration were included in the experiment. Since columns are critical elements needed to prevent structural collapse, knowledge of their integrity and damage conditions is essential for safety after exposure to blast loads. In this research, a concrete column with embedded SAs was chosen as the specimen, and a series of explosive tests were conducted on the column. Experimental results reveal that surface damages, though appear severe, cause minor changes in the damage index, and through cracks result in significant increase of the damage index, demonstrating the effectiveness of the active sensing, enabled by embedded SAs, in damage monitoring of the column under blast loads, and thus providing a reliable indication of structural integrity in the event of blast loads. PMID:29710807

The circumstellar ring of SN 1987A

NASA Astrophysics Data System (ADS)

Fransson, Claes; Migotto, Katia; Larsson, Josefin; Pesce, Dominic; Challis, Peter; Chevalier, Roger A.; France, Kevin; Kirshner, Robert P.; Leibundgut, Bruno; Lundqvist, Peter; McCray, Richard; Spyromilio, Jason; Taddia, Francesco; Jerkstrand, Anders; Mattila, Seppo; Smith, Nathan; Sollerman, Jesper; Wheeler, J. Craig; Crotts, Arlin; Garnavich, Peter; Heng, Kevin; Lawrence, Stephen S.; Panagia, Nino; Pun, Chun S. J.; Sonneborn, George; Sugerman, Ben

2016-06-01

The circumstellar ring of supernova 1987A first became visible a few months after the explosion due to photoionisation by the supernova flash. From 1995 hotspots appeared in the ring and their brightness increased nearly exponentially as a result of interaction with the supernova blast wave. Imaging and spectroscopic observations with the Hubble Space Telescope and the Very Large Telescope now show that both the shocked and the unshocked emission components from the ring have been decreasing since ~ 2009. In addition, the most recent images reveal the brightening of new spots outside the ring. These observations indicate that the hotspots are being dissolved by the shocks and that the blast wave is now expanding and interacting with dense clumps beyond the ring. Based on the currently observed decay we predict that the ring will be destroyed by ~ 2025, while the blast wave will reveal the distribution of gas as it expands outside the ring, thus tracing the mass-loss history of the supernova progenitor.

Optical shaping of gas targets for laser–plasma ion sources

DOE PAGES

Dover, N. P.; Cook, N.; Tresca, O.; ...

2016-02-09

In this paper, we report on the experimental demonstration of a technique to generate steep density gradients in gas-jet targets of interest to laser–plasma ion acceleration. By using an intentional low-energy prepulse, we generated a hydrodynamic blast wave in the gas to shape the target prior to the arrival of an intense COmore » $$_{2}$$($${\\it\\lambda}\\approx 10~{\\rm\\mu}\\text{m}$$) drive pulse. This technique has been recently shown to facilitate the generation of ion beams by shockwave acceleration (Trescaet al.,Phys. Rev. Lett., vol. 115 (9), 2015, 094802). Here, we discuss and introduce a model to understand the generation of these blast waves and discuss in depth the experimental realisation of the technique, supported by hydrodynamics simulations. With appropriate prepulse energy and timing, this blast wave can generate steepened density gradients as short as$$l\\approx 20~{\\rm\\mu}\\text{m}$$($1/e$), opening up new possibilities for laser–plasma studies with near-critical gaseous targets.« less

Synaptic Mechanisms of Blast-Induced Brain Injury

PubMed Central

Przekwas, Andrzej; Somayaji, Mahadevabharath R.; Gupta, Raj K.

2016-01-01

Blast wave-induced traumatic brain injury (TBI) is one of the most common injuries to military personnel. Brain tissue compression/tension due to blast-induced cranial deformations and shear waves due to head rotation may generate diffuse micro-damage to neuro-axonal structures and trigger a cascade of neurobiological events culminating in cognitive and neurodegenerative disorders. Although diffuse axonal injury is regarded as a signature wound of mild TBI (mTBI), blast loads may also cause synaptic injury wherein neuronal synapses are stretched and sheared. This synaptic injury may result in temporary disconnect of the neural circuitry and transient loss in neuronal communication. We hypothesize that mTBI symptoms such as loss of consciousness or dizziness, which start immediately after the insult, could be attributed to synaptic injury. Although empirical evidence is beginning to emerge; the detailed mechanisms underlying synaptic injury are still elusive. Coordinated in vitro–in vivo experiments and mathematical modeling studies can shed light into the synaptic injury mechanisms and their role in the potentiation of mTBI symptoms. PMID:26834697

Lasting retinal injury in a mouse model of blast-induced trauma

USDA-ARS?s Scientific Manuscript database

Traumatic brain injury (TBI) due to blast exposure is currently the most prevalent of war injuries. While secondary ocular blast injuries due to flying debris are more common, primary ocular blast exposure has been reported among survivors of explosions, but with limited understanding of the resulti...

Updates to Blast Injury Criteria Models for Nuclear Casualty Estimation

DTIC Science & Technology

2015-12-01

the likelihood of blast-related injury use a two-step process. First, the maximum velocity obtained by the human body or secondary missile is determined...the human body . Secondary injuries are caused by missiles that are accelerated by the blast wave. Tertiary injuries are caused by the acceleration of...the human body and the ensuing deceleration. In this work, we focus on secondary and tertiary injuries. Because of the dramatic effects experienced

Underbody Blast Models of TBI Caused by Hyper-Acceleration and Secondary Head Impact

DTIC Science & Technology

2016-02-01

discovery rate (FDR), which controls for the expected proportion of false rejected hypotheses. ANOVA was performed to evaluate the significance in gene...acceleration/deceleration11,27 and blast4,13 have also been designed for the purpose of evaluating coup-contrecoup and blast wave energies potentially... evaluation of different angles/ locations of the projectile impact to the surface of the rat head. Finally, pilot studies were conducted to provide further

Ultrahigh energy neutrino afterglows of nearby long duration gamma-ray bursts

NASA Astrophysics Data System (ADS)

Thomas, Jessymol K.; Moharana, Reetanjali; Razzaque, Soebur

2017-11-01

Detection of ultrahigh energy (UHE, ≳1 PeV ) neutrinos from astrophysical sources will be a major advancement in identifying and understanding the sources of UHE cosmic rays (CRs) in nature. Long duration gamma-ray burst (GRB) blast waves have been considered as potential acceleration sites of UHECRs. These CRs are expected to interact with GRB afterglow photons, which are synchrotron radiation from relativistic electrons coaccelerated with CRs in the blast wave, and naturally produce UHE neutrinos. Fluxes of these neutrinos are uncertain, however, and crucially depend on the observed afterglow modeling. We have selected a sample of 23 long duration GRBs within redshift 0.5 for which adequate electromagnetic afterglow data are available and which could produce high flux of UHE afterglow neutrinos, being nearby. We fit optical, x-ray, and γ -ray afterglow data with an adiabatic blast wave model in a constant density interstellar medium and in a wind environment where the density of the wind decreases as the inverse square of the radius from the center of the GRB. The blast wave model parameters extracted from these fits are then used for calculating UHECR acceleration and p γ interactions to produce UHE neutrino fluxes from these GRBs. We have also explored the detectability of these neutrinos by currently running and upcoming large area neutrino detectors, such as the Pierre Auger Observatory, IceCube Gen-2, and KM3NeT observatories. We find that our realistic flux models from nearby GRBs will be unconstrained in the foreseeable future.

Off-center blast in a shocked medium

NASA Astrophysics Data System (ADS)

Duncan-Miller, G. C.; Stone, W. D.

2018-07-01

When multiple blasts occur at different times, the situation arises in which a blast wave is propagating into a medium that has already been shocked. Determining the evolution in the shape of the second shock is not trivial, as it is propagating into air that is not only non-uniform, but also non-stationary. To accomplish this task, we employ the method of Kompaneets to determine the shape of a shock in a non-uniform media. We also draw from the work of Korycansky (Astrophys J 398:184-189. https://doi.org/10.1086/171847 , 1992) on an off-center explosion in a medium with radially varying density. Extending this to treat non-stationary flow, and making use of approximations to the Sedov solution for the point blast problem, we are able to determine an analytic expression for the evolving shape of the second shock. In particular, we consider the case of a shock in air at standard ambient temperature and pressure, with the second shock occurring shortly after the original blast wave reaches it, as in a sympathetic detonation.

The Foulness Multiton Air Blast Simulator. Part 3. Blast Wave Formation and Methods Used to Drive the Simulator,

DTIC Science & Technology

1980-03-01

the total energy release of the explosive driver using expanded polystyrene and at the same time, controlling the rate of release. The part played by aqueous foam in minimising irregularities in waveform also is described. (Author)

The Complexity of Biomechanics Causing Primary Blast-Induced Traumatic Brain Injury: A Review of Potential Mechanisms

PubMed Central

Courtney, Amy; Courtney, Michael

2015-01-01

Primary blast-induced traumatic brain injury (bTBI) is a prevalent battlefield injury in recent conflicts, yet biomechanical mechanisms of bTBI remain unclear. Elucidating specific biomechanical mechanisms is essential to developing animal models for testing candidate therapies and for improving protective equipment. Three hypothetical mechanisms of primary bTBI have received the most attention. Because translational and rotational head accelerations are primary contributors to TBI from non-penetrating blunt force head trauma, the acceleration hypothesis suggests that blast-induced head accelerations may cause bTBI. The hypothesis of direct cranial transmission suggests that a pressure transient traverses the skull into the brain and directly injures brain tissue. The thoracic hypothesis of bTBI suggests that some combination of a pressure transient reaching the brain via the thorax and a vagally mediated reflex result in bTBI. These three mechanisms may not be mutually exclusive, and quantifying exposure thresholds (for blasts of a given duration) is essential for determining which mechanisms may be contributing for a level of blast exposure. Progress has been hindered by experimental designs, which do not effectively expose animal models to a single mechanism and by over-reliance on poorly validated computational models. The path forward should be predictive validation of computational models by quantitative confirmation with blast experiments in animal models, human cadavers, and biofidelic human surrogates over a range of relevant blast magnitudes and durations coupled with experimental designs, which isolate a single injury mechanism. PMID:26539158

29 CFR 1926.906 - Initiation of explosive charges-electric blasting.

Code of Federal Regulations, 2013 CFR

2013-07-01

...” position at all times, except when firing. It shall be so designed that the firing lines to the cap circuit... blasting machine shall not be in excess of its rated capacity. Furthermore, in primary blasting, a series..., shall use only blasting galvanometers or other instruments that are specifically designed for this...

29 CFR 1926.906 - Initiation of explosive charges-electric blasting.

Code of Federal Regulations, 2014 CFR

2014-07-01

...” position at all times, except when firing. It shall be so designed that the firing lines to the cap circuit... blasting machine shall not be in excess of its rated capacity. Furthermore, in primary blasting, a series..., shall use only blasting galvanometers or other instruments that are specifically designed for this...

29 CFR 1926.906 - Initiation of explosive charges-electric blasting.

Code of Federal Regulations, 2012 CFR

2012-07-01

...” position at all times, except when firing. It shall be so designed that the firing lines to the cap circuit... blasting machine shall not be in excess of its rated capacity. Furthermore, in primary blasting, a series..., shall use only blasting galvanometers or other instruments that are specifically designed for this...

29 CFR 1926.906 - Initiation of explosive charges-electric blasting.

Code of Federal Regulations, 2011 CFR

2011-07-01

...” position at all times, except when firing. It shall be so designed that the firing lines to the cap circuit... blasting machine shall not be in excess of its rated capacity. Furthermore, in primary blasting, a series..., shall use only blasting galvanometers or other instruments that are specifically designed for this...

Blast waves from detonated military explosive reduce GluR1 and synaptophysin levels in hippocampal slice cultures✩

PubMed Central

Smith, Marquitta; Piehler, Thuvan; Benjamin, Richard; Farizatto, Karen L.; Pait, Morgan C.; Almeida, Michael F.; Ghukasyan, Vladimir V.; Bahr, Ben A.

2017-01-01

Explosives create shockwaves that cause blast-induced neurotrauma, one of the most common types of traumatic brain injury (TBI) linked to military service. Blast-induced TBIs are often associated with reduced cognitive and behavioral functions due to a variety of factors. To study the direct effects of military explosive blasts on brain tissue, we removed systemic factors by utilizing rat hippocampal slice cultures. The long-term slice cultures were briefly sealed air-tight in serum-free medium, lowered into a 37 °C water-filled tank, and small 1.7-gram assemblies of cyclotrimethylene trinitramine (RDX) were detonated 15 cm outside the tank, creating a distinct shockwave recorded at the culture plate position. Compared to control mock-treated groups of slices that received equal submerge time, 1–3 blast impacts caused a dose-dependent reduction in the AMPA receptor subunit GluR1. While only a small reduction was found in hippocampal slices exposed to a single RDX blast and harvested 1–2 days later, slices that received two consecutive RDX blasts 4 min apart exhibited a 26–40% reduction in GluR1, and the receptor subunit was further reduced by 64–72% after three consecutive blasts. Such loss correlated with increased levels of HDAC2, a histone deacetylase implicated in stress-induced reduction of glutamatergic transmission. No evidence of synaptic marker recovery was found at 72 h post-blast. The presynaptic marker synaptophysin was found to have similar susceptibility as GluR1 to the multiple explosive detonations. In contrast to the synaptic protein reductions, actin levels were unchanged, spectrin breakdown was not detected, and Fluoro-Jade B staining found no indication of degenerating neurons in slices exposed to three RDX blasts, suggesting that small, sub-lethal explosives are capable of producing selective alterations to synaptic integrity. Together, these results indicate that blast waves from military explosive cause signs of synaptic compromise without producing severe neurodegeneration, perhaps explaining the cognitive and behavioral changes in those blast-induced TBI sufferers that have no detectable neuropathology. PMID:27720798

The injured eye

PubMed Central

Scott, Robert

2011-01-01

Eye injuries come at a high cost to society and are avoidable. Ocular blast injuries can be primary, from the blast wave itself; secondary, from fragments carried by the blast wind; tertiary; due to structural collapse or being thrown against a fixed object; or quaternary, from burns and indirect injuries. Ballistic eye protection significantly reduces the incidence of eye injuries and should be encouraged from an early stage in Military training. Management of an injured eye requires meticulous history taking, evaluation of vision that measures the acuity and if there is a relative pupillary defect as well as careful inspection of the eyes, under anaesthetic if necessary. A lateral canthotomy with cantholysis should be performed immediately if there is a sight-threatening retrobulbar haemorrhage. Systemic antibiotics should be prescribed if there is a suspected penetrating or perforating injury. A ruptured globe should be protected by an eye shield. Primary repair of ruptured globes should be performed in a timely fashion. Secondary procedures will often be required at a later date to achieve sight preservation. A poor initial visual acuity is not a guarantee of a poor final result. The final result can be predicted after approximately 3–4 weeks. Future research in eye injuries attempts to reduce scarring and neuronal damage as well as to promote photoreceptor rescue, using post-transcriptional inhibition of cell death pathways and vaccination to promote neural recovery. Where the sight has been lost sensory substitution of a picture from a spectacle mounted video camera to the touch receptors of the tongue can be used to achieve appreciation of the outside world. PMID:21149360

Time variation in the reaction-zone structure of two-phase spray detonations.

NASA Technical Reports Server (NTRS)

Pierce, T. H.; Nicholls, J. A.

1973-01-01

A detailed theoretical analysis of the time-varying detonation structure in a monodisperse spray is presented. The theory identifies experimentally observed reaction-zone overpressures as deriving from blast waves formed therein by the explosive ignition of the spray droplets, and follows in time the motion, change in strength, and interactions of these blast waves with one another, and with the leading shock. The results are compared with experimental data by modeling the motion of a finite-size circular pressure transducer through the theoretical data field in an x-t space.

Dynamic Pressure Impulse for Near-Ideal and Non-Ideal Blast Waves -- Height of Burst Charts. Supplement

DTIC Science & Technology

1983-12-31

Law 79-565), 22 April 1967. Other requests shall be referred to Director, Defense Nuclear Agency, Washington, DC 20305- 10101. THIS WORK WAS SPONSORED...JPUMNTNYNOTATIO This work was sponsored by the Defense Nuclear Agency under RDT&E RMSS Code 8344082466 Y99QAXSGO0039 H25900. I?. cosASI comR I& SUISCI TM...displacement which a vehicle exposed to a blast wave sufers can be used as a measure of the dynamic pressure impulse it receives. ,hat is, the vehicle

Astrophysical blast wave data

DOE Office of Scientific and Technical Information (OSTI.GOV)

Riley, Nathan; Geissel, Matthias; Lewis, Sean M

2015-03-01

The data described in this document consist of image files of shadowgraphs of astrophysically relevant laser driven blast waves. Supporting files include Mathematica notebooks containing design calculations, tabulated experimental data and notes, and relevant publications from the open research literature. The data was obtained on the Z-Beamlet laser from July to September 2014. Selected images and calculations will be published as part of a PhD dissertation and in associated publications in the open research literature, with Sandia credited as appropriate. The authors are not aware of any restrictions that could affect the release of the data.

Structural Changes in Lipid Vesicles Generated by the Shock Blast Waves: Coarse-Grained Molecular Dynamics Simulation

DTIC Science & Technology

2013-11-01

duration, or shock-pulse shape. Used in this computational study is a coarse-grained model of the lipid vesicle as a simplified model of a cell...Figures iv List of Tables iv 1. Introduction 1 2. Model and Methods 3 3. Results and Discussion 6 3.1 Simulation of the Blast Waves with Low Peak...realistic detail but to focus on a simple model of the major constituent of a cell membrane, the phospholipid bilayer. In this work, we studied the

Blast-wave model description of the Hanbury-Brown-Twiss radii in pp collisions at LHC energies

NASA Astrophysics Data System (ADS)

Bialas, Andrzej; Florkowski, Wojciech; Zalewski, Kacper

2015-04-01

The blast wave model is applied to the recent data on Hanbury-Brown-Twiss radii in pp collisions, measured by the ALICE Collaboration. A reasonable description of data is obtained for a rather low temperature of the kinetic freeze-out, T≃ 100 MeV, and the transverse profile corresponding to the emission from a shell of a fairly small width 2δ ˜ 1.5 fm. The size and the life-time of the produced system are determined for various multiplicities of the produced particles.

Another self-similar blast wave: Early time asymptote with shock heated electrons and high thermal conductivity

NASA Technical Reports Server (NTRS)

Cox, D. P.; Edgar, R. J.

1982-01-01

Accurate approximations are presented for the self-similar structures of nonradiating blast waves with adiabatic ions, isothermal electrons, and equation ion and electron temperatures at the shock. The cases considered evolve in cavities with power law ambient densities (including the uniform density case) and have negligible external pressure. The results provide the early time asymptote for systems with shock heating of electrons and strong thermal conduction. In addition, they provide analytical results against which two fluid numerical hydrodynamic codes can be checked.

Blast Wave Experiments at Z

DTIC Science & Technology

2007-06-01

radiation flows upward, it passes though a 1.7-mm high, tapered, 25-μm thick gold wall cone that is filled 20 ± 3 mg/cm3 silica aerogel (SiO2). Above...this cone is a 20 ± 3 mg/cm3 silica aerogel filled, 1-mm high, 2.4-mm inner diameter, 25-μm thick gold wall cylinder. On the cylinder rests a 4-mm...diameter gold platform that supports a higher density (40-60 mg/cm3) silica aerogel . This aerogel is the region where the blast wave forms after

Internal ballistics of the detonation products of a blast-hole charge

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mangush, S.K.; Garbunov, V.A.

1986-07-01

The authors investigate the gasdynamic flow of the detonation products of a blast-hole charge (the expansion of the detonation products in the blast hole and the gas outflow and propagation of shock airwaves into the face space). The problem is solved by means of a numerical program for integration of partial differential equations of one-dimensional gas-dynamics. A numerical model of the internal ballistics of a blast-hole charge is presented. In addition to the variation of the thermodynamic parameters in the blast hole, the formation of the shock wave in the face space is shown, which is the source of gasmore » ignition. Further development of the numerical model of the action of blast-hole charges is planned which will involve an analysis of a number of applied problems.« less

Bomb blast mass casualty incidents: initial triage and management of injuries.

PubMed

Goh, S H

2009-01-01

Bomb blast injuries are no longer confined to battlefields. With the ever present threat of terrorism, we should always be prepared for bomb blasts. Bomb blast injuries tend to affect air-containing organs more, as the blast wave tends to exert a shearing force on air-tissue interfaces. Commonly-injured organs include the tympanic membranes, the sinuses, the lungs and the bowel. Of these, blast lung injury is the most challenging to treat. The clinical picture is a mix of acute respiratory distress syndrome and air embolism, and the institution of positive pressure ventilation in the presence of low venous pressures could cause systemic arterial air embolism. The presence of a tympanic membrane perforation is not a reliable indicator of the presence of a blast injury in the other air-containing organs elsewhere. Radiological imaging of the head, chest and abdomen help with the early identification of blast lung injury, head injury, abdominal injury, eye and sinus injuries, as well as any penetration by foreign bodies. In addition, it must be borne in mind that bomb blasts could also be used to disperse radiological and chemical agents.

Mandibular fractures in British military personnel secondary to blast trauma sustained in Iraq and Afghanistan.

PubMed

Breeze, J; Gibbons, A J; Hunt, N C; Monaghan, A M; Gibb, I; Hepper, A; Midwinter, M

2011-12-01

Blast trauma is the primary cause of maxillofacial injury sustained by British service personnel on deployment, and the mandible is the maxillofacial structure most likely to be injured in combat, but there are few reports about the effect of blast trauma on it. The Joint Theatre Trauma Registry identified all mandibular fractures sustained by British servicemen secondary to blast injury between 1 January 2004 and 30 September 2009. These were matched to corresponding hospital notes from the Royal Centre for Defence Medicine (RCDM) for those evacuated servicemen and autopsy records for those who died of wounds. Seventy-four mandibular fractures were identified in 60 servicemen. Twenty-two soldiers were evacuated to the RCDM and the remaining 38 died from wounds. Fractures of the symphysis (39/106, 37%) and body (31/106, 29%) were more common than those of the angle (26/106, 25%) and condyle (10/106, 9%). This pattern of injury differs from that of civilian blunt trauma where the condyle is the site that is injured most often. Those fractures thought to result from the blast wave itself usually caused simple localised fractures, whereas those fractures thought to result from fragments of the blast caused comminution that affected several areas of the mandible. The pattern of fractures in personnel injured while they were inside a vehicle resembled that traditionally seen in blunt trauma, which supports the requirement for mandatory wearing of seat-belts in the rear of vehicles whenever tactically viable. All mandibular fractures in servicemen injured while in the turret of a vehicle had evidence of foreign bodies or radio-opaque fragments as a result of their exposed position. Many of these injuries could therefore be potentially prevented by the adoption of facial protection. Copyright © 2010 The British Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.

Photographic laboratory studies of explosions.

NASA Technical Reports Server (NTRS)

Kamel, M. M.; Oppenheim, A. K.

1973-01-01

Description of a series of cinematographic studies of explosions made with a high-speed rotating-mirror streak camera which uses a high-frequency stroboscopic ruby laser as the light source. The results obtained mainly concern explosions initiated by focused laser irradiation from a pulsed neodymium laser in a detonating gas consisting essentially of an equimolar mixture of acetylene and oxygen at an initial pressure of 100 torr at room temperature. Among the most significant observations were observations of a spherical blast wave preceded by a Chapman-Jouguet detonation which is stabilized immediately after initiation, the merging of a spherical flame with a shock front of the blast wave in which the flame is propagating, the division of a spherical detonation front into a shock wave and flame, and the generation of shock waves by a network of spherical flames.

Molecular Signatures and Diagnostic Biomarkers of Cumulative, Blast-Graded Mild TBI

DTIC Science & Technology

2012-10-01

These results are in agreement with data obtained using non-blast TBI models (Diet- rich et al., 2004; Maegele et al., 2007). Moreover, CX3CL1 chemokine...the shoulder at Figure 1A), substantially contaminating the blast wave in the direction of shock tube axis (Figure 1A). In addition, the exhaust...highly spe- cific for the CNS and is present in platelets and red blood cells (see Svetlov et al., 2009 for review). In previous studies, we reported a

In Silico Investigation of Intracranial Blast Mitigation with Relevance to Military Traumatic Brain Injury

DTIC Science & Technology

2010-09-01

how personal protective equipment affects the brain’s response to blasts. In this study we investigated the effect of the Advanced Combat...analyzing stress wave propagation, which is the main dynamic effect loading the brain tissue during a blast event. We consider two key metrics of stress ...Cauchy stress tensor, and sij ¼ σij − 13σkkδij are the compo- nents of the deviatoric stress tensor (24). Fig. 1 shows snapshots of the pressure

The Acceleration of Charged Particles at a Spherical Shock Moving through an Irregular Magnetic Field

DOE Office of Scientific and Technical Information (OSTI.GOV)

Giacalone, J.

We investigate the physics of charged-particle acceleration at spherical shocks moving into a uniform plasma containing a turbulent magnetic field with a uniform mean. This has applications to particle acceleration at astrophysical shocks, most notably, to supernovae blast waves. We numerically integrate the equations of motion of a large number of test protons moving under the influence of electric and magnetic fields determined from a kinematically defined plasma flow associated with a radially propagating blast wave. Distribution functions are determined from the positions and velocities of the protons. The unshocked plasma contains a magnetic field with a uniform mean andmore » an irregular component having a Kolmogorov-like power spectrum. The field inside the blast wave is determined from Maxwell’s equations. The angle between the average magnetic field and unit normal to the shock varies with position along its surface. It is quasi-perpendicular to the unit normal near the sphere’s equator, and quasi-parallel to it near the poles. We find that the highest intensities of particles, accelerated by the shock, are at the poles of the blast wave. The particles “collect” at the poles as they approximately adhere to magnetic field lines that move poleward from their initial encounter with the shock at the equator, as the shock expands. The field lines at the poles have been connected to the shock the longest. We also find that the highest-energy protons are initially accelerated near the equator or near the quasi-perpendicular portion of the shock, where the acceleration is more rapid.« less

Collimation and Asymmetry of the Hot Blast Wave from the Recurrent Nova V745 Sco

NASA Astrophysics Data System (ADS)

Drake, Jeremy J.; Delgado, Laura; Laming, J. Martin; Starrfield, Sumner; Kashyap, Vinay; Orlando, Salvatore; Page, Kim L.; Hernanz, M.; Ness, J.-U.; Gehrz, R. D.; van Rossum, Daan; Woodward, Charles E.

2016-07-01

The recurrent symbiotic nova V745 Sco exploded on 2014 February 6 and was observed on February 22 and 23 by the Chandra X-ray Observatory Transmission Grating Spectrometers. By that time the supersoft source phase had already ended, and Chandra spectra are consistent with emission from a hot, shock-heated circumstellar medium with temperatures exceeding 107 K. X-ray line profiles are more sharply peaked than expected for a spherically symmetric blast wave, with a full width at zero intensity of approximately 2400 km s-1, an FWHM of 1200 ± 30 km s-1, and an average net blueshift of 165 ± 10 km s-1. The red wings of lines are increasingly absorbed toward longer wavelengths by material within the remnant. We conclude that the blast wave was sculpted by an aspherical circumstellar medium in which an equatorial density enhancement plays a role, as in earlier symbiotic nova explosions. Expansion of the dominant X-ray-emitting material is aligned close to the plane of the sky and is most consistent with an orbit seen close to face-on. Comparison of an analytical blast wave model with the X-ray spectra, Swift observations, and near-infrared line widths indicates that the explosion energy was approximately 1043 erg and confirms an ejected mass of approximately 10-7 M ⊙. The total mass lost is an order of magnitude lower than the accreted mass required to have initiated the explosion, indicating that the white dwarf is gaining mass and is a Type Ia supernova progenitor candidate.

Ground vibration monitoring for construction blasting in urban areas

DOT National Transportation Integrated Search

2001-04-01

The primary objectives of this study were to determine a recommendation for the pre-blast area for surveys, and to obtain actual field vibrations from rock blasting operations, in populated regions within specific geologic units. The area confined wi...

Ultrafast Fabry-Perot fiber-optic pressure sensors for multimedia blast event measurements.

PubMed

Zou, Xiaotian; Wu, Nan; Tian, Ye; Zhang, Yang; Fitek, John; Maffeo, Michael; Niezrecki, Christopher; Chen, Julie; Wang, Xingwei

2013-02-20

A shock wave (SW) is characterized as a large pressure fluctuation that typically lasts only a few milliseconds. On the battlefield, SWs pose a serious threat to soldiers who are exposed to explosions, which may lead to blast-induced traumatic brain injuries. SWs can also be used beneficially and have been applied to a variety of medical treatments due to their unique interaction with tissues and cells. Consequently, it is important to have sensors that can quantify SW dynamics in order to better understand the physical interaction between body tissue and the incident acoustic wave. In this paper, the ultrafast fiber-optic sensor based on the Fabry-Perot interferometric principle was designed and four such sensors were fabricated to quantify a blast event within different media, simultaneously. The compact design of the fiber-optic sensor allows for a high degree of spatial resolution when capturing the wavefront of the traveling SW. Several blast event experiments were conducted within different media (e.g., air, rubber membrane, and water) to evaluate the sensor's performance. This research revealed valuable knowledge for further study of SW behavior and SW-related applications.

A Wireless Intracranial Brain Deformation Sensing System for Blast-Induced Traumatic Brain Injury

PubMed Central

Song, S.; Race, N. S.; Kim, A.; Zhang, T.; Shi, R.; Ziaie, B.

2015-01-01

Blast-induced traumatic brain injury (bTBI) has been linked to a multitude of delayed-onset neurodegenerative and neuropsychiatric disorders, but complete understanding of their pathogenesis remains elusive. To develop mechanistic relationships between bTBI and post-blast neurological sequelae, it is imperative to characterize the initiating traumatic mechanical events leading to eventual alterations of cell, tissue, and organ structure and function. This paper presents a wireless sensing system capable of monitoring the intracranial brain deformation in real-time during the event of a bTBI. The system consists of an implantable soft magnet and an external head-mounted magnetic sensor that is able to measure the field in three dimensions. The change in the relative position of the soft magnet WITH respect to the external sensor as the result of the blast wave induces changes in the magnetic field. The magnetic field data in turn is used to extract the temporal and spatial motion of the brain under the blast wave in real-time. The system has temporal and spatial resolutions of 5 μs and 10 μm. Following the characterization and validation of the sensor system, we measured brain deformations in a live rodent during a bTBI. PMID:26586273

Combined Effects of Primary and Tertiary Blast on Rat Brain: Characterization of a Model of Blast-induced Mild Traumatic Brain Injury

DTIC Science & Technology

2014-03-01

military environments, affected in- dividuals (e.g. football players) often sustain additional mild injuries. mTBI symptoms are typically mild and... concussion andmild traumatic brain injury. PM R 3, S354–358; DOI:10.1016/j.pmrj.2011.07.017 (2011). 2. Hendricks, A. M. et al. Screening for mild traumatic...Mendez, M. F. et al. Mild traumatic brain injury from primary blast vs. blunt forces: post- concussion consequences and functional neuroimaging

Blast Injuries: From Improvised Explosive Device Blasts to the Boston Marathon Bombing.

PubMed

Singh, Ajay K; Ditkofsky, Noah G; York, John D; Abujudeh, Hani H; Avery, Laura A; Brunner, John F; Sodickson, Aaron D; Lev, Michael H

2016-01-01

Although most trauma centers have experience with the imaging and management of gunshot wounds, in most regions blast wounds such as the ones encountered in terrorist attacks with the use of improvised explosive devices (IEDs) are infrequently encountered outside the battlefield. As global terrorism becomes a greater concern, it is important that radiologists, particularly those working in urban trauma centers, be aware of the mechanisms of injury and the spectrum of primary, secondary, tertiary, and quaternary blast injury patterns. Primary blast injuries are caused by barotrauma from the initial increased pressure of the explosive detonation and the rarefaction of the atmosphere immediately afterward. Secondary blast injuries are caused by debris carried by the blast wind and most often result in penetrating trauma from small shrapnel. Tertiary blast injuries are caused by the physical displacement of the victim and the wide variety of blunt or penetrating trauma sustained as a result of the patient impacting immovable objects such as surrounding cars, walls, or fences. Quaternary blast injuries include all other injuries, such as burns, crush injuries, and inhalational injuries. Radiography is considered the initial imaging modality for assessment of shrapnel and fractures. Computed tomography is the optimal test to assess penetrating chest, abdominal, and head trauma. The mechanism of blast injuries and the imaging experience of the victims of the Boston Marathon bombing are detailed, as well as musculoskeletal, neurologic, gastrointestinal, and pulmonary injury patterns from blast injuries. ©RSNA, 2016.

Stochastic Lanchester Air-To-Air Campaign Model: Methods Used to Generate Model Outputs and a User’s Guide: 2007

DTIC Science & Technology

2007-05-01

only the non-dimensional parameter Kill Rate Ra- tio = KRR = κ = kb/kr: . [Eq. 2-6] 1(0)Pexcept0(0)P Mmb,κPmP Nnr, nPP ;NnrandMmb ,nPκPm)Pnκ(mP NM,nm...varies with explosive yield E. Dy- namic overpressure p is proportional to the square of the air velocity v immedi- ately behind the blast wave ...ρ and the time t required for the blast wave to reach the locations of interest. According to the principles of dimensional analysis, v can be

Combining Advanced Turbulent Mixing and Combustion Models with Advanced Multi-Phase CFD Code to Simulate Detonation and Post-Detonation Bio-Agent Mixing and Destruction

DTIC Science & Technology

2017-10-01

perturbations in the energetic material to study their effects on the blast wave formation. The last case also makes use of the same PBX, however, the...configuration, Case A: Spore cloud located on the top of the charge at an angle 45 degree, Case B: Spore cloud located at an angle 45 degree from the charge...theoretical validation. The first is the Sedov case where the pressure decay and blast wave front are validated based on analytical solutions. In this test

Computation of viscous blast wave flowfields

NASA Technical Reports Server (NTRS)

Atwood, Christopher A.

1991-01-01

A method to determine unsteady solutions of the Navier-Stokes equations was developed and applied. The structural finite-volume, approximately factored implicit scheme uses Newton subiterations to obtain the spatially and temporally second-order accurate time history of the interaction of blast-waves with stationary targets. The inviscid flux is evaluated using MacCormack's modified Steger-Warming flux or Roe flux difference splittings with total variation diminishing limiters, while the viscous flux is computed using central differences. The use of implicit boundary conditions in conjunction with a telescoping in time and space method permitted solutions to this strongly unsteady class of problems. Comparisons of numerical, analytical, and experimental results were made in two and three dimensions. These comparisons revealed accurate wave speed resolution with nonoscillatory discontinuity capturing. The purpose of this effort was to address the three-dimensional, viscous blast-wave problem. Test cases were undertaken to reveal these methods' weaknesses in three regimes: (1) viscous-dominated flow; (2) complex unsteady flow; and (3) three-dimensional flow. Comparisons of these computations to analytic and experimental results provided initial validation of the resultant code. Addition details on the numerical method and on the validation can be found in the appendix. Presently, the code is capable of single zone computations with selection of any permutation of solid wall or flow-through boundaries.

Skull flexure as a contributing factor in the mechanism of injury in the rat when exposed to a shock wave.

PubMed

Bolander, Richard; Mathie, Blake; Bir, Cynthia; Ritzel, David; VandeVord, Pamela

2011-10-01

The manner in which energy from an explosion is transmitted into the brain is currently a highly debated topic within the blast injury community. This study was conducted to investigate the injury biomechanics causing blast-related neurotrauma in the rat. Biomechanical responses of the rat head under shock wave loading were measured using strain gauges on the skull surface and a fiber optic pressure sensor placed within the cortex. MicroCT imaging techniques were applied to quantify skull bone thickness. The strain gauge results indicated that the response of the rat skull is dependent on the intensity of the incident shock wave; greater intensity shock waves cause greater deflections of the skull. The intracranial pressure (ICP) sensors indicated that the peak pressure developed within the brain was greater than the peak side-on external pressure and correlated with surface strain. The bone plates between the lambda, bregma, and midline sutures are probable regions for the greatest flexure to occur. The data provides evidence that skull flexure is a likely candidate for the development of ICP gradients within the rat brain. This dependency of transmitted stress on particular skull dynamics for a given species should be considered by those investigating blast-related neurotrauma using animal models.

Shock waves; Proceedings of the 18th International Symposium, Sendai, Japan, July 21-26, 1991. Vols. 1 & 2

NASA Astrophysics Data System (ADS)

Takayama, Kazuyoshi

Various papers on shock waves are presented. The general topics addressed include: shock wave structure, propagation, and interaction; shock wave reflection, diffraction, refraction, and focusing; shock waves in condensed matter; shock waves in dusty gases and multiphase media; hypersonic flows and shock waves; chemical processes and related combustion phenomena; explosions, blast waves, and laser initiation of shock waves; shock tube technology and instrumentation; CFD of shock wave phenomena; medical applications and biological effects; industrial applications.

A Numerical Study on the Screening of Blast-Induced Waves for Reducing Ground Vibration

NASA Astrophysics Data System (ADS)

Park, Dohyun; Jeon, Byungkyu; Jeon, Seokwon

2009-06-01

Blasting is often a necessary part of mining and construction operations, and is the most cost-effective way to break rock, but blasting generates both noise and ground vibration. In urban areas, noise and vibration have an environmental impact, and cause structural damage to nearby structures. Various wave-screening methods have been used for many years to reduce blast-induced ground vibration. However, these methods have not been quantitatively studied for their reduction effect of ground vibration. The present study focused on the quantitative assessment of the effectiveness in vibration reduction of line-drilling as a screening method using a numerical method. Two numerical methods were used to analyze the reduction effect toward ground vibration, namely, the “distinct element method” and the “non-linear hydrocode.” The distinct element method, by particle flow code in two dimensions (PFC 2D), was used for two-dimensional parametric analyses, and some cases of two-dimensional analyses were analyzed three-dimensionally using AUTODYN 3D, the program of the non-linear hydrocode. To analyze the screening effectiveness of line-drilling, parametric analyses were carried out under various conditions, with the spacing, diameter of drill holes, distance between the blasthole and line-drilling, and the number of rows of drill holes, including their arrangement, used as parameters. The screening effectiveness was assessed via a comparison of the vibration amplitude between cases both with and without screening. Also, the frequency distribution of ground motion of the two cases was investigated through fast Fourier transform (FFT), with the differences also examined. From our study, it was concluded that line-drilling as a screening method of blast-induced waves was considerably effective under certain design conditions. The design details for field application have also been proposed.

Low-cost rapid miniature optical pressure sensors for blast wave measurements.

PubMed

Wu, Nan; Wang, Wenhui; Tian, Ye; Zou, Xiaotian; Maffeo, Michael; Niezrecki, Christopher; Chen, Julie; Wang, Xingwei

2011-05-23

This paper presents an optical pressure sensor based on a Fabry-Perot (FP) interferometer formed by a 45° angle polished single mode fiber and an external silicon nitride diaphragm. The sensor is comprised of two V-shape grooves with different widths on a silicon chip, a silicon nitride diaphragm released on the surface of the wider V-groove, and a 45° angle polished single mode fiber. The sensor is especially suitable for blast wave measurements: its compact structure ensures a high spatial resolution; its thin diaphragm based design and the optical demodulation scheme allow a fast response to the rapid changing signals experienced during blast events. The sensor shows linearity with the correlation coefficient of 0.9999 as well as a hysteresis of less than 0.3%. The shock tube test demonstrated that the sensor has a rise time of less than 2 µs from 0 kPa to 140 kPa.

Mabs monograph, air blast instrumentation, 1943-1993 measurement techniques and instrumentation. Volume 1. The nuclear era. 1945-1963. Technical report, 17 September 1992-31 May 1994

DOE Office of Scientific and Technical Information (OSTI.GOV)

Reisler, R.E.; Keefer, J.H.; Ethridge, N.H.

1995-03-01

Blast wave measurement techniques and instrumentation developed by Military Applications of Blast Simulators (MABS) participating countries to study blast phenomena during the nuclear era are summarized. Passive and active gages both mechanical self-recording and electronic systems deployed on kiloton and megaton explosive tests during the period 1945-1963 are presented. The country and the year the gage was introduced are included with the description. References are also provided. Volume 2 covers measurement techniques and instrumentation for the period 1959-1993 and Volume 3 covers structural target and gage calibration from 1943 to 1993.

Skull Flexure from Blast Waves: A Mechanism for Brain Injury with Implications for Helmet Design

DOE Office of Scientific and Technical Information (OSTI.GOV)

Moss, W C; King, M J; Blackman, E G

2009-04-30

Traumatic brain injury [TBI] has become a signature injury of current military conflicts, with debilitating, costly, and long-lasting effects. Although mechanisms by which head impacts cause TBI have been well-researched, the mechanisms by which blasts cause TBI are not understood. From numerical hydrodynamic simulations, we have discovered that non-lethal blasts can induce sufficient skull flexure to generate potentially damaging loads in the brain, even without a head impact. The possibility that this mechanism may contribute to TBI has implications for injury diagnosis and armor design.

COLLIMATION AND ASYMMETRY OF THE HOT BLAST WAVE FROM THE RECURRENT NOVA V745 Sco

DOE Office of Scientific and Technical Information (OSTI.GOV)

Drake, Jeremy J.; Kashyap, Vinay; Delgado, Laura

The recurrent symbiotic nova V745 Sco exploded on 2014 February 6 and was observed on February 22 and 23 by the Chandra X-ray Observatory Transmission Grating Spectrometers. By that time the supersoft source phase had already ended, and Chandra spectra are consistent with emission from a hot, shock-heated circumstellar medium with temperatures exceeding 10{sup 7} K. X-ray line profiles are more sharply peaked than expected for a spherically symmetric blast wave, with a full width at zero intensity of approximately 2400 km s{sup 1}, an FWHM of 1200 ± 30 km s{sup 1}, and an average net blueshift of 165more » ± 10 km s{sup 1}. The red wings of lines are increasingly absorbed toward longer wavelengths by material within the remnant. We conclude that the blast wave was sculpted by an aspherical circumstellar medium in which an equatorial density enhancement plays a role, as in earlier symbiotic nova explosions. Expansion of the dominant X-ray-emitting material is aligned close to the plane of the sky and is most consistent with an orbit seen close to face-on. Comparison of an analytical blast wave model with the X-ray spectra, Swift observations, and near-infrared line widths indicates that the explosion energy was approximately 10{sup 43} erg and confirms an ejected mass of approximately 10{sup 7} M {sub ⊙}. The total mass lost is an order of magnitude lower than the accreted mass required to have initiated the explosion, indicating that the white dwarf is gaining mass and is a Type Ia supernova progenitor candidate.« less

BLAST BIOLOGY. Technical Progress Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

White, C.S.; Richmond, D.R.

1959-09-18

Experimental data regarding the biologic consequences of exposure to several environmental variations associated with actual and simulated explosive detonations were reviewed. Blast biology is discussed relative to primary, secondary, tentiary, and miscellaneous blast effects as those attributable, respectively, to variations in environmental pressure, trauma from blast-produced missiles (both penetrating and nonpenetrating), the consequences of physical displacement of biological targets by blast-produced winds, and hazards due to ground shock, dust, and thermal phenomena not caused by thermal radiation per se. Primary blast effects were considered, noting physical-biophysical factors contributing to the observed pathophysiology. A simple hydrostatic model was utilized diagrammatically inmore » pointing out possible etiologic mechanisms. The gross biologic response to single. "fast"-rising overpressures were described as was the tolerance of mice, rats, guinea pigs. and rabbits to "long"-duration pressure pulses rising "rapidly" in single and double steps. Data regarding biological response to "slowly" rising over-pressures of "long" duration are discussed. Attention was called to the similarities under certain circumstances between thoracic trauma from nonpenetrating missiles and that noted from air blast. The association between air emboli, increase in lung weight (hemorrhage and edema), and mortality was discussed. Data relevant to the clinical symptoms and therapy of blast injury are presented. The relation of blast hazards to nuclear explosions was assessed and one approach to predicting the maximal potential casualties from blast phenomena is presented making use of arbitrary and tentative criteria. (auth)« less

The effect of suppressors and muzzle brakes on shock wave strength

NASA Astrophysics Data System (ADS)

Phan, K. C.; Stollery, J. L.

Experimental simulations of a gun blast were performed in the course of an optimization study of shock-wave suppressor and muzzle-brake geometry. A single-spark schlieren system was used to photograph the shock waves emerging from a 32-mm shock tube. The suppressor systems tested with respect to the overpressure level included a perforated tube enclosed in an expansion chamber, a cup-and-box suppressor, and noise-absorbent materials inside a suppressor; high suppression efficiency was observed for the first two. Recoil simulation tests, performed with plain and pyramidal baffles, disk, and cylinder, show that the blast level is generally higher for a more efective muzzle brake. An optimum distance from the muzzle to the brake is suggested to be in the region of one caliber.

Navier-Stokes simulations of unsteady transonic flow phenomena

NASA Technical Reports Server (NTRS)

Atwood, C. A.

1992-01-01

Numerical simulations of two classes of unsteady flows are obtained via the Navier-Stokes equations: a blast-wave/target interaction problem class and a transonic cavity flow problem class. The method developed for the viscous blast-wave/target interaction problem assumes a laminar, perfect gas implemented in a structured finite-volume framework. The approximately factored implicit scheme uses Newton subiterations to obtain the spatially and temporally second-order accurate time history of the blast-waves with stationary targets. The inviscid flux is evaluated using either of two upwind techniques, while the full viscous terms are computed by central differencing. Comparisons of unsteady numerical, analytical, and experimental results are made in two- and three-dimensions for Couette flows, a starting shock-tunnel, and a shock-tube blockage study. The results show accurate wave speed resolution and nonoscillatory discontinuity capturing of the predominantly inviscid flows. Viscous effects were increasingly significant at large post-interaction times. While the blast-wave/target interaction problem benefits from high-resolution methods applied to the Euler terms, the transonic cavity flow problem requires the use of an efficient scheme implemented in a geometrically flexible overset mesh environment. Hence, the Reynolds averaged Navier-Stokes equations implemented in a diagonal form are applied to the cavity flow class of problems. Comparisons between numerical and experimental results are made in two-dimensions for free shear layers and both rectangular and quieted cavities, and in three-dimensions for Stratospheric Observatory For Infrared Astronomy (SOFIA) geometries. The acoustic behavior of the rectangular and three-dimensional cavity flows compare well with experiment in terms of frequency, magnitude, and quieting trends. However, there is a more rapid decrease in computed acoustic energy with frequency than observed experimentally owing to numerical dissipation. In addition, optical phase distortion due to the time-varying density field is modelled using geometrical constructs. The computed optical distortion trends compare with the experimentally inferred result, but underpredicts the fluctuating phase difference magnitude.

Attenuation of blast pressure behind ballistic protective vests.

PubMed

Wood, Garrett W; Panzer, Matthew B; Shridharani, Jay K; Matthews, Kyle A; Capehart, Bruce P; Myers, Barry S; Bass, Cameron R

2013-02-01

Clinical studies increasingly report brain injury and not pulmonary injury following blast exposures, despite the increased frequency of exposure to explosive devices. The goal of this study was to determine the effect of personal body armour use on the potential for primary blast injury and to determine the risk of brain and pulmonary injury following a blast and its impact on the clinical care of patients with a history of blast exposure. A shock tube was used to generate blast overpressures on soft ballistic protective vests (NIJ Level-2) and hard protective vests (NIJ Level-4) while overpressure was recorded behind the vest. Both types of vest were found to significantly decrease pulmonary injury risk following a blast for a wide range of conditions. At the highest tested blast overpressure, the soft vest decreased the behind armour overpressure by a factor of 14.2, and the hard vest decreased behind armour overpressure by a factor of 56.8. Addition of body armour increased the 50th percentile pulmonary death tolerance of both vests to higher levels than the 50th percentile for brain injury. These results suggest that ballistic protective body armour vests, especially hard body armour plates, provide substantial chest protection in primary blasts and explain the increased frequency of head injuries, without the presence of pulmonary injuries, in protected subjects reporting a history of blast exposure. These results suggest increased clinical suspicion for mild to severe brain injury is warranted in persons wearing body armour exposed to a blast with or without pulmonary injury.

[Indirect blast rupture of the pancreas with a primary unperforated blast injury of the duodenum].

PubMed

Ignjatović, Dragan; Ignjatović, Mile; Jevtić, Miodrag

2006-02-01

To present a patient with an indirect blast rupture of the head of pancreas, as well as with a blast contusion of the duodenum following abdominal gunshot injury. A patient with the abdominal gunshot injury was submitted to the management of the injury of the liver, gaster and the right kidney in the field hospital. The revealed rupture of the head of the pancreas and the contusion of the duodenum were managed applying the method of Whipple. Indirect blast injuries require extensive surgical interventions, especially under war conditions.

Improvements to the Sandia CTH Hydro-Code to Support Blast Analysis and Protective Design of Military Vehicles

DTIC Science & Technology

2014-04-15

used for advertising or product endorsement purposes. 6.0 REFERENCES [1] McGlaun, J., Thompson, S. and Elrick, M. “CTH: A Three-Dimensional Shock-Wave...Validation of a Loading Model for Simulating Blast Mine Effects on Armoured Vehicles,” 7 th International LS-DYNA Users Conference, Detroit, MI 2002. [14

A Bulk Comptonization Model for the Prompt GRB Emission and its Relation to the Fermi GRB Spectra

NASA Technical Reports Server (NTRS)

Kazanas, Demosthenes

2010-01-01

We present a model in which the GRB prompt emission at E E(sub peak) is due to bulk Comptonization by the relativistic blast wave motion of either its own synchrotron photons of ambient photons of the stellar configuration that gave birth to the GRB. The bulk Comptonization process then induces the production of relativistic electrons of Lorentz factor equal to that of the blast wave through interactions with its ambient protons. The inverse compton emission of these electrons produces a power law component that extends to multi GeV energies in good agreement with the LAT GRB observations.

Analysis of dynamical response of air blast loaded safety device

NASA Astrophysics Data System (ADS)

Tropkin, S. N.; Tlyasheva, R. R.; Bayazitov, M. I.; Kuzeev, I. R.

2018-03-01

Equipment of many oil and gas processing plants in the Russian Federation is considerably worn-out. This causes the decrease of reliability and durability of equipment and rises the accident rate. An air explosion is the one of the most dangerous cases for plants in oil and gas industry, usually caused by uncontrolled emission and inflammation of oil products. Air explosion can lead to significant danger for life and health of plant staff, so it necessitates safety device usage. A new type of a safety device is designed. Numerical simulation is necessary to analyse design parameters and performance of the safety device, subjected to air blast loading. Coupled fluid-structure interaction analysis is performed to determine strength of the protective device and its performance. The coupled Euler-Lagrange method, allowable in Abaqus by SIMULIA, is selected as the most appropriate analysis tool to study blast wave interaction with the safety device. Absorption factors of blast wave are evaluated for the safety device. This factors allow one to assess efficiency of the safety device, and its main structural component – dampener. Usage of CEL allowed one to model fast and accurately the dampener behaviour, and to develop the parametric model to determine safety device sizes.

Wireless device for activation of an underground shock wave absorber

NASA Astrophysics Data System (ADS)

Chikhradze, M.; Akhvlediani, I.; Bochorishvili, N.; Mataradze, E.

2011-10-01

The paper describes the mechanism and design of the wireless device for activation of energy absorber for localization of blast energy in underground openings. The statistics shows that the greatest share of accidents with fatal results associate with explosions in coal mines due to aero-methane and/or air-coal media explosion. The other significant problem is terrorist or accidental explosions in underground structures. At present there are different protective systems to reduce the blast energy. One of the main parts of protective Systems is blast Identification and Registration Module. The works conducted at G. Tsulukidze Mining Institute of Georgia enabled to construct the wireless system of explosion detection and mitigation of shock waves. The system is based on the constant control on overpressure. The experimental research continues to fulfill the system based on both threats, on the constant control on overpressure and flame parameters, especially in underground structures and coal mines. Reaching the threshold value of any of those parameters, the system immediately starts the activation. The absorber contains a pyrotechnic device ensuring the discharge of dispersed water. The operational parameters of wireless device and activation mechanisms of pyrotechnic element of shock wave absorber are discussed in the paper.

Tsunami Generation from Asteroid Airburst and Ocean Impact and Van Dorn Effect

NASA Technical Reports Server (NTRS)

Robertson, Darrel

2016-01-01

Airburst - In the simulations explored energy from the airburst couples very weakly with the water making tsunami dangerous over a shorter distance than the blast for asteroid sizes up to the maximum expected size that will still airburst (approx.250MT). Future areas of investigation: - Low entry angle airbursts create more cylindrical blasts and might couple more efficiently - Bursts very close to the ground will increase coupling - Inclusion of thermosphere (>80km altitude) may show some plume collapse effects over a large area although with much less pressure center dot Ocean Impact - Asteroid creates large cavity in ocean. Cavity backfills creating central jet. Oscillation between the cavity and jet sends out tsunami wave packet. - For deep ocean impact waves are deep water waves (Phase speed = 2x Group speed) - If the tsunami propagation and inundation calculations are correct for the small (<250MT) asteroids in these simulations where they impact deep ocean basins, the resulting tsunami is not a significant hazard unless particularly close to vulnerable communities. Future work: - Shallow ocean impact. - Effect of continental shelf and beach profiles - Tsunami vs. blast damage radii for impacts close to populated areas - Larger asteroids below presumed threshold of global effects (Ø200 - 800m).

Reconstruction of Axial Energy Deposition in Magnetic Liner Inertial Fusion Based on PECOS Shadowgraph Unfolds Using the AMR Code FLASH

NASA Astrophysics Data System (ADS)

Adams, Marissa; Jennings, Christopher; Slutz, Stephen; Peterson, Kyle; Gourdain, Pierre; U. Rochester-Sandia Collaboration

2017-10-01

Magnetic Liner Inertial Fusion (MagLIF) experiments incorporate a laser to preheat a deuterium filled capsule before compression via a magnetically imploding liner. In this work, we focus on the blast wave formed in the fuel during the laser preheat component of MagLIF, where approximately 1kJ of energy is deposited in 3ns into the capsule axially before implosion. To model blast waves directly relevant to experiments such as MagLIF, we inferred deposited energy from shadowgraphy of laser-only experiments preformed at the PECOS target chamber using the Z-Beamlet laser. These energy profiles were used to initialize 2-dimensional simulations using by the adaptive mesh refinement code FLASH. Gradients or asymmetries in the energy deposition may seed instabilities that alter the fuel's distribution, or promote mix, as the blast wave interacts with the liner wall. The AMR capabilities of FLASH allow us to study the development and dynamics of these instabilities within the fuel and their effect on the liner before implosion. Sandia Natl Labs is managed by NTES of Sandia, LLC., a subsidiary of Honeywell International, Inc, for the U.S. DOEs NNSA under contract DE-NA0003525.

Bioceramic inlays do not improve mechanical incorporation of grit-blasted titanium stems in the proximal sheep femur.

PubMed

Keränen, Pauli; Koort, Jyri; Itälä, Ari; Ylänen, Heimo; Dalstra, Michel; Hupa, Mikko; Kommonen, Bertel; Aro, Hannu T

2010-03-15

The aim of the present study was to determine, if bioactive glass (BG) surface inlays improve osseointegration of titanium implants in the proximal femur of adult sheep. In simulation of uncemented primary stems (nine animals), only the proximal part of the implants was grit-blasted and three surface slots of the grit-blasted region were filled with sintered BG microspheres. Primary stems were implanted using press-fit technique. In revision stem simulation (eight animals), grit-blasting was extended over the whole implant and seven perforating holes of the stem were filled by sintered BG granules. Revision stems were implanted with a mixture of autogenous bone graft and BG granules. Comparison with solid partially or fully grit-blasted control stems implanted in the contralateral femurs was performed in the primary and revision stem experiments at 12 and 25 weeks, respectively. Implant incorporation was evaluated by torsional failure testing and histomorphometry. Only one-third of the primary stems anchored mechanically to bone. The revision stems incorporated better and the BG inlays of the revision stems showed ingrowth of new bone. However, there were no significant differences in the torsional failure loads between the stems with BG inlays and the control stems. In conclusion, surface BG inlays gave no measurable advantage in mechanical incorporation of grit-blasted titanium implants. Overall, the proximal sheep femur, characterized by minimal amount of cancellous bone and the presence of adipocytic bone marrow, seemed to present compromised bone healing conditions. (c) 2009 Wiley Periodicals, Inc.

Detection of Blast-Related Traumatic Brain Injury in U.S. Military Personnel

DTIC Science & Technology

2011-06-02

hypothesis that blast-related traumatic brain injury causes traumatic axonal injury, using diffusion tensor imaging ( DTI ), an advanced form of magnetic... DTI scanning within 90 days after the injury. All the subjects had primary blast exposure plus another, blast-related mecha- nism of injury (e.g...other injuries but no clinical diagnosis of traumatic brain injury. Results Abnormalities revealed on DTI were consistent with traumatic axonal injury in

Blast-Induced Tinnitus and Elevated Central Auditory and Limbic Activity in Rats: A Manganese-Enhanced MRI and Behavioral Study.

PubMed

Ouyang, Jessica; Pace, Edward; Lepczyk, Laura; Kaufman, Michael; Zhang, Jessica; Perrine, Shane A; Zhang, Jinsheng

2017-07-07

Blast-induced tinitus is the number one service-connected disability that currently affects military personnel and veterans. To elucidate its underlying mechanisms, we subjected 13 Sprague Dawley adult rats to unilateral 14 psi blast exposure to induce tinnitus and measured auditory and limbic brain activity using manganese-enhanced MRI (MEMRI). Tinnitus was evaluated with a gap detection acoustic startle reflex paradigm, while hearing status was assessed with prepulse inhibition (PPI) and auditory brainstem responses (ABRs). Both anxiety and cognitive functioning were assessed using elevated plus maze and Morris water maze, respectively. Five weeks after blast exposure, 8 of the 13 blasted rats exhibited chronic tinnitus. While acoustic PPI remained intact and ABR thresholds recovered, the ABR wave P1-N1 amplitude reduction persisted in all blast-exposed rats. No differences in spatial cognition were observed, but blasted rats as a whole exhibited increased anxiety. MEMRI data revealed a bilateral increase in activity along the auditory pathway and in certain limbic regions of rats with tinnitus compared to age-matched controls. Taken together, our data suggest that while blast-induced tinnitus may play a role in auditory and limbic hyperactivity, the non-auditory effects of blast and potential traumatic brain injury may also exert an effect.

Isochoric heating and strong blast wave formation driven by fast electrons in solid-density targets

NASA Astrophysics Data System (ADS)

Santos, J. J.; Vauzour, B.; Touati, M.; Gremillet, L.; Feugeas, J.-L.; Ceccotti, T.; Bouillaud, R.; Deneuville, F.; Floquet, V.; Fourment, C.; Hadj-Bachir, M.; Hulin, S.; Morace, A.; Nicolaï, Ph; d'Oliveira, P.; Reau, F.; Samaké, A.; Tcherbakoff, O.; Tikhonchuk, V. T.; Veltcheva, M.; Batani, D.

2017-10-01

We experimentally investigate the fast (< 1 {ps}) isochoric heating of multi-layer metallic foils and subsequent high-pressure hydrodynamics induced by energetic electrons driven by high-intensity, high-contrast laser pulses. The early-time temperature profile inside the target is measured from the streaked optical pyrometry of the target rear side. This is further characterized from benchmarked simulations of the laser-target interaction and the fast electron transport. Despite a modest laser energy (< 1 {{J}}), the early-time high pressures and associated gradients launch inwards a strong compression wave developing over ≳ 10 ps into a ≈ 140 {Mbar} blast wave, according to hydrodynamic simulations, consistent with our measurements. These experimental and numerical findings pave the way to a short-pulse-laser-based platform dedicated to high-energy-density physics studies.

Mobile, Multimodal, Label-Free Imaging Probe Analysis of Choroidal Oximetry and Retinal Hypoxia

DTIC Science & Technology

2017-12-01

these same eye injuries. Primary blast-induced injury (PBI), which can occur in eyes that are not punctured or ruptured by the blast, is correlated ...optimization. (1A-F) The component of our PBI- devices, output pressure detection sensor, amplifier, and input pressure panel. (1G) Correlation between...by changing the setting of blast generator. (2A-B) Correlation between output pressure and blast time duration. (2C) After PBI- treatment, the eyes of

Blast injury from explosive munitions.

PubMed

Cernak, I; Savic, J; Ignjatovic, D; Jevtic, M

1999-07-01

To evaluate the effect of blast in common war injuries. One thousand three hundred and three patients injured by explosive munitions and demonstrating extremity wounds without other penetrating injuries were admitted to the Military Medical Academy in Belgrade between 1991 and 1994. Of these, 665 patients (51%) had symptoms and physical signs that were compatible with the clinical diagnosis of primary blast injury, whereas the remaining 658 patients did not. Random sampling of 65 patients in the blast group during the early posttraumatic period showed statistically significant elevations in blood thromboxane A2 (TxA2), prostacyclin (PGI2), and sulfidopeptide leukotrienes compared with the random sample of 62 patients in the nonblast group. This difference could not be accounted for by differing injury severity between the groups, because the severity of wounds as measured by both the Injury Severity Score and the Red Cross Wound Classification was similar in both groups. Amongst blast patients, 200 patients (30%) had long-term (1 year) symptoms and signs reflecting central nervous system disorders. These symptoms and signs were only sporadically found in 4% of the nonblast patients. These findings indicate that primary blast injury is more common in war injuries than previously thought and that of those affected by blast, a surprisingly high proportion retain long-term neurologic disability. The elevation in eicosanoids could be used to confirm and monitor blast injury. In relation to the immediate management of patients injured by explosive weapons, it follows that particular attention should be paid to the presence and/or development of blast injury. Our findings indicate that blast is more common in war injuries than previously thought. Eicosanoid changes after blast injury suggest that blast injury causes a major physiologic stress. A variety of effects on the central nervous system suggest that blast injury could be responsible for some aspects of what is now considered to be the posttraumatic stress disorder.

Airblast Simulator Studies.

DTIC Science & Technology

1984-02-01

RAREFACTION WAVE ELIMINATOR CONSIDERATIONS 110 5.1 FLIP CALCULATIONS 110 5.2 A PASSIVE/ACTIVE RWE 118 6 DISTRIBUTED FUEL AIR EXPLOSIVES 120 REFERENCES 123 TA...conventional and distributed-charge fuel- air explosive charges used in a study of the utility of distributed charge FAE systems for blast simulation. The...limited investigation of distributed charge fuel air explosive configurations for blast simulator applications. During the course of this study

Ozone formation behind pulsed-laser-generated blast waves in oxygen

NASA Astrophysics Data System (ADS)

Stricker, J.; Parker, J. G.

1984-12-01

The formation of ozone behind blast waves in oxygen generated by a pulsed laser has been investigated both experimentally and theoretically, over cell pressure range of 0.68-27 atm. Ozone buildup formed by successive pulses was monitored by recording UV absorption at 2540 Å. It was found that, as the number of pulses increase, the rate of ozone formation decreased until finally an equilibrium concentration was reached. This equilibrium magnitude was determined by the condition that the number of ozone molecules produced by the wave equals the number decomposed by the same wave. The decomposition and formation of O3 during a single pulse were monitored by time-resolved UV absorption measurements. In order to provide a fundamental basis for interpretation of the mechanism of ozone formation, a mathematical model was developed. Although qualitatively measurements and theory agree, the data, mainly on the number of O3 molecules produced per pulse, is in significant disagreement. Several possible explanations of this discrepancy are given.

The ratio between corner frequencies of source spectra of P- and S-waves—a new discriminant between earthquakes and quarry blasts

NASA Astrophysics Data System (ADS)

Ataeva, G.; Gitterman, Y.; Shapira, A.

2017-01-01

This study analyzes and compares the P- and S-wave displacement spectra from local earthquakes and explosions of similar magnitudes. We propose a new approach to discrimination between low-magnitude shallow earthquakes and explosions by using ratios of P- to S-wave corner frequencies as a criterion. We have explored 2430 digital records of the Israeli Seismic Network (ISN) from 456 local events (226 earthquakes, 230 quarry blasts, and a few underwater explosions) of magnitudes Md = 1.4-3.4, which occurred at distances up to 250 km during 2001-2013 years. P-wave and S-wave displacement spectra were computed for all events following Brune's source model of earthquakes (1970, 1971) and applying the distance correction coefficients (Shapira and Hofstetter, Teconophysics 217:217-226, 1993; Ataeva G, Shapira A, Hofstetter A, J Seismol 19:389-401, 2015), The corner frequencies and moment magnitudes were determined using multiple stations for each event, and then the comparative analysis was performed.

Activity of Bruton's tyrosine-kinase inhibitor ibrutinib in patients with CD117-positive acute myeloid leukaemia: a mechanistic study using patient-derived blast cells.

PubMed

Rushworth, Stuart A; Pillinger, Genevra; Abdul-Aziz, Amina; Piddock, Rachel; Shafat, Manar S; Murray, Megan Y; Zaitseva, Lyubov; Lawes, Matthew J; MacEwan, David J; Bowles, Kristian M

2015-05-01

Roughly 80% of patients with acute myeloid leukaemia have high activity of Bruton's tyrosine-kinase (BTK) in their blast cells compared with normal haemopoietic cells, rendering the cells sensitive to the oral BTK inhibitor ibrutinib in vitro. We aimed to develop the biological understanding of the BTK pathway in acute myeloid leukaemia to identify clinically relevant diagnostic information that might define a subset of patients that should respond to ibrutinib treatment. We obtained acute myeloid leukaemia blast cells from unselected patients attending our UK hospital between Feb 19, 2010, and Jan 20, 2014. We isolated primary acute myeloid leukaemia blast cells from heparinised blood and human peripheral blood mononuclear cells to establish the activity of BTK in response to CD117 activation. Furthermore, we investigated the effects of ibrutinib on CD117-induced BTK activation, downstream signalling, adhesion to primary bone-marrow mesenchymal stromal cells, and proliferation of primary acute myeloid leukaemia blast cells. We used the Mann-Whitney U test to compare results between groups. We obtained acute myeloid leukaemia blast cells from 29 patients. Ibrutinib significantly inhibited CD117-mediated proliferation of primary acute myeloid leukaemia blast cells (p=0·028). CD117 activation increased BTK activity by inducing phosphorylated BTK in patients with CD117-positive acute myeloid leukaemia. Furthermore, ibrutinib inhibited CD117-induced activity of BTK and downstream kinases at a concentration of 100 nM or more. CD117-mediated adhesion of CD117-expressing blast cells to bone-marrow stromal cells was significantly inhibited by Ibrutinib at 500 nM (p=0·028) INTERPRETATION: As first-in-man clinical trials of ibrutinib in patients with acute myeloid leukaemia commence, the data suggest not all patients will respond. Our findings show that BTK has specific pro-tumoural biological actions downstream of surface CD117 activation, which are inhibited by ibrutinib. Accordingly, we propose that patients with acute myeloid leukaemia whose blast cells express CD117 should be considered for forthcoming clinical trials of ibrutinib. Worldwide Cancer Research, The Big C, UK National Institutes for Health Research, the Humane Research Trust, the Department of Higher Education and Research of the Libyan Government, and Norwich Research Park. Copyright © 2015 Elsevier Ltd. All rights reserved.

The influence of clothing on human intrathoracic pressure during airblast.

PubMed

Young, A J; Jaeger, J J; Phillips, Y Y; Yelverton, J T; Richmond, D R

1985-01-01

Exposure to airblast can result in injury to the lungs and other gas-containing organs. The mechanism of lung injury is not clearly understood, but may be related to the rapid increase in intrathoracic pressure (ITP) which is produced when the blast wave strikes the chest wall. The purpose of this study was to determine if ITP during airblast would be influenced by several different types of protective clothing. Ten healthy young male volunteers were exposed to airblast while standing face-on and wearing 1) military fatigues (control condition); 2) fatigues with field jacket; 3) fatigues with ballistic armor vest; 4) fatigues with ceramic vest; 5) fatigues with ceramic vest over the ballistic vest. The incident blast waves simulated artillery muzzle blast. In each subject, an esophageal strain-gauge pressure transducer measured ITP during the blast. The pressure signal was analyzed for ITPmax, and maximum rate of rise of ITP (dP X dt max-1). In addition, the power density spectra of each ITP wave was computed and the peak frequency (fp) and centroid frequency (fc) were calculated. When the subjects wore the ballistic vest, the mean ITPmax was higher (p less than 0.05) than when they were exposed to airblast in fatigues alone. ITPmax was not influenced by the other clothing ensembles. The mean dP X dtmax-1 was not significantly different with any protective clothing ensemble. Clothing had no significant effect of fp, but with the ballistic vest, the mean calculated fc was higher (p less than 0.05) than that for the fatigues alone.(ABSTRACT TRUNCATED AT 250 WORDS)

Concussive brain injury from explosive blast

PubMed Central

de Lanerolle, Nihal C; Hamid, Hamada; Kulas, Joseph; Pan, Jullie W; Czlapinski, Rebecca; Rinaldi, Anthony; Ling, Geoffrey; Bandak, Faris A; Hetherington, Hoby P

2014-01-01

Objective Explosive blast mild traumatic brain injury (mTBI) is associated with a variety of symptoms including memory impairment and posttraumatic stress disorder (PTSD). Explosive shock waves can cause hippocampal injury in a large animal model. We recently reported a method for detecting brain injury in soldiers with explosive blast mTBI using magnetic resonance spectroscopic imaging (MRSI). This method is applied in the study of veterans exposed to blast. Methods The hippocampus of 25 veterans with explosive blast mTBI, 20 controls, and 12 subjects with PTSD but without exposure to explosive blast were studied using MRSI at 7 Tesla. Psychiatric and cognitive assessments were administered to characterize the neuropsychiatric deficits and compare with findings from MRSI. Results Significant reductions in the ratio of N-acetyl aspartate to choline (NAA/Ch) and N-acetyl aspartate to creatine (NAA/Cr) (P < 0.05) were found in the anterior portions of the hippocampus with explosive blast mTBI in comparison to control subjects and were more pronounced in the right hippocampus, which was 15% smaller in volume (P < 0.05). Decreased NAA/Ch and NAA/Cr were not influenced by comorbidities – PTSD, depression, or anxiety. Subjects with PTSD without blast had lesser injury, which tended to be in the posterior hippocampus. Explosive blast mTBI subjects had a reduction in visual memory compared to PTSD without blast. Interpretation The region of the hippocampus injured differentiates explosive blast mTBI from PTSD. MRSI is quite sensitive in detecting and localizing regions of neuronal injury from explosive blast associated with memory impairment. PMID:25493283

Mechanical Damage of Tympanic Membrane in Relation to Impulse Pressure Waveform – A Study in Chinchillas

PubMed Central

Gan, Rong Z.; Nakmali, Don; Ji, Xiao D.; Leckness, Kegan; Yokell, Zachary

2016-01-01

Mechanical damage to middle ear components in blast exposure directly causes hearing loss, and the rupture of the tympanic membrane (TM) is the most frequent injury of the ear. However, it is unclear how the severity of injury graded by different patterns of TM rupture is related to the overpressure waveforms induced by blast waves. In the present study, the relationship between the TM rupture threshold and the impulse or overpressure waveform has been investigated in chinchillas. Two groups of animals were exposed to blast overpressure simulated in our lab under two conditions: open field and shielded with a stainless steel cup covering the animal head. Auditory brainstem response (ABR) and wideband tympanometry were measured before and after exposure to check the hearing threshold and middle ear function. Results show that waveforms recorded in the shielded case were different from those in the open field and the TM rupture threshold in the shielded case was lower than that in the open field (3.4±0.7 vs. 9.1±1.7 psi or 181±1.6 vs. 190±1.9 dB SPL). The impulse pressure energy spectra analysis of waveforms demonstrates that the shielded waveforms include greater energy at high frequencies than that of the open field waves. Finally, a 3D finite element (FE) model of the chinchilla ear was used to compute the distributions of stress in the TM and the TM displacement with impulse pressure waves. The FE model-derived change of stress in response to pressure loading in the shielded case was substantially faster than that in the open case. This finding provides the biomechanical mechanisms for blast induced TM damage in relation to overpressure waveforms. The TM rupture threshold difference between the open and shielded cases suggests that an acoustic role of helmets may exist, intensifying ear injury during blast exposure. PMID:26807796

Forensic Seismology: constraints on terrorist bombings

NASA Astrophysics Data System (ADS)

Wallace, T. C.; Koper, K. D.

2002-05-01

Seismology has long been used as a tool to monitor and investigate explosions, both accidental and intentional. Seismic records can be used to provide a precise chronology of events, estimate the energy release in explosions and produce constraints to test various scenarios for the explosions. Truck bombs are a popular tool of terrorists, and at least two such attacks have been recorded seismically. On August 7, 1998 a truck bomb was detonated near the US embassy in Nairobi, Kenya. The bomb seriously damaging a dozen buildings, injuring more than 4000 people and causing 220 fatalities. The explosion was recorded on a short-period seismometer located north of the blast site; the blast seismogram contained body waves, Rayleigh waves and vibrations associated with the air blast. Modeling of the body and surfaces wave allowed an estimate of the origin time of the bombing, which it turn could be used as a constraint the timing of the air blasts. The speed of the air waves from an explosion depend on the air temperature and the size, or yield, of the explosion. In an effort to fully utilize the seismic recordings from such attacks, we analyzed the seismic records from a series of controlled truck bomb explosions carried out at White Sand Missile Range in New Mexico. We developed a new set of scaling laws that relate seismic and acoustic observations directly to the explosive mass (yield). These relationships give a yield of approximately 3000 kg of TNT equivalent for the Nairobi bomb. The terrorist bombing of the Murrah Federal Building in Oklahoma City in 1995 was also recorded on seismometers. One of these records showed 2 discrete surface wavetrains separated by approximately 10 seconds. Some groups seized on the seismic recordings as evidence that there were 2 explosions, and that the US government was actually behind the bombing. However, the USGS monitored the demolition of the remainder of the Murrah Building and showed that the collapse also produced 2 surface waves. The interpretation is that one group was the fundamental mode Rayleigh wave while the other was either a higher-mode surface wave or a scattered S-wave (Lg like) packet (Holzer et al, 1996). This example illustrates the utility of forensic seismology for testing various hypothesis for the explosions. As the number of permanent and temporarily installed seismometers increase in the next decade, the number of "exotic" sources recorded and investigated is grow dramatically. These studies can be very useful for investigating terrorist attacks, and developing scenarios for the crimes.

Vascular and Inflammatory Factors in the Pathophysiology of Blast-Induced Brain Injury

PubMed Central

Elder, Gregory A.; Gama Sosa, Miguel A.; De Gasperi, Rita; Stone, James Radford; Dickstein, Dara L.; Haghighi, Fatemeh; Hof, Patrick R.; Ahlers, Stephen T.

2015-01-01

Blast-related traumatic brain injury (TBI) has received much recent attention because of its frequency in the conflicts in Iraq and Afghanistan. This renewed interest has led to a rapid expansion of clinical and animal studies related to blast. In humans, high-level blast exposure is associated with a prominent hemorrhagic component. In animal models, blast exerts a variety of effects on the nervous system including vascular and inflammatory effects that can be seen with even low-level blast exposures which produce minimal or no neuronal pathology. Acutely, blast exposure in animals causes prominent vasospasm and decreased cerebral blood flow along with blood-brain barrier breakdown and increased vascular permeability. Besides direct effects on the central nervous system, evidence supports a role for a thoracically mediated effect of blast; whereby, pressure waves transmitted through the systemic circulation damage the brain. Chronically, a vascular pathology has been observed that is associated with alterations of the vascular extracellular matrix. Sustained microglial and astroglial reactions occur after blast exposure. Markers of a central and peripheral inflammatory response are found for sustained periods after blast injury and include elevation of inflammatory cytokines and other inflammatory mediators. At low levels of blast exposure, a microvascular pathology has been observed in the presence of an otherwise normal brain parenchyma, suggesting that the vasculature may be selectively vulnerable to blast injury. Chronic immune activation in brain following vascular injury may lead to neurobehavioral changes in the absence of direct neuronal pathology. Strategies aimed at preventing or reversing vascular damage or modulating the immune response may improve the chronic neuropsychiatric symptoms associated with blast-related TBI. PMID:25852632

Engine Cycle Analysis of Air Breathing Microwave Rocket with Reed Valves

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fukunari, Masafumi; Komatsu, Reiji; Yamaguchi, Toshikazu

The Microwave Rocket is a candidate for a low cost launcher system. Pulsed plasma generated by a high power millimeter wave beam drives a blast wave, and a vehicle acquires impulsive thrust by exhausting the blast wave. The thrust generation process of the Microwave Rocket is similar to a pulse detonation engine. In order to enhance the performance of its air refreshment, the air-breathing mechanism using reed valves is under development. Ambient air is taken to the thruster through reed valves. Reed valves are closed while the inside pressure is high enough. After the time when the shock wave exhaustsmore » at the open end, an expansion wave is driven and propagates to the thrust-wall. The reed valve is opened by the negative gauge pressure induced by the expansion wave and its reflection wave. In these processes, the pressure oscillation is important parameter. In this paper, the pressure oscillation in the thruster was calculated by CFD combined with the flux through from reed valves, which is estimated analytically. As a result, the air-breathing performance is evaluated using Partial Filling Rate (PFR), the ratio of thruster length to diameter L/D, and ratio of opening area of reed valves to superficial area {alpha}. An engine cycle and predicted thrust was explained.« less

Shock Initiated Reactions of Reactive Multiphase Blast Explosives

NASA Astrophysics Data System (ADS)

Wilson, Dennis; Granier, John; Johnson, Richard; Littrell, Donald

2015-06-01

This paper describes a new class of reactive multiphase blast explosives (RMBX) and characterization of their blast characteristics. These RMBXs are non-ideal explosive compositions of perfluoropolyether (PFPE), nano aluminum, and a micron-size high-density reactive metal - Tantalum, Zirconium, or Zinc in mass loadings of 66 to 83 percent. Unlike high explosives, these PFPE-metal compositions release energy via a fast self-oxidized combustion wave (rather than a true self-sustaining detonation) that is shock dependent, and can be overdriven to control energy release rate. The term ``reactive multiphase blast'' refers to the post-dispersion blast behavior: multiphase in that there are a gas phase that imparts pressure and a solid (particulate) phase that imparts momentum; and reactive in that the hot metal particles react with atmospheric oxygen and the explosive gas products to give an extended pressure pulse. The RMBX formulations were tested in two spherical core-shell geometries - an RMBX shell exploded by a high explosive core, and an RMBX core imploded by a high explosive shell. The fireball and blast characteristics were compared to a C-4 baseline charge.

Retinal ganglion cell damage in an experimental rodent model of blast-mediated traumatic brain injury.

PubMed

Mohan, Kabhilan; Kecova, Helga; Hernandez-Merino, Elena; Kardon, Randy H; Harper, Matthew M

2013-05-15

To evaluate retina and optic nerve damage following experimental blast injury. Healthy adult mice were exposed to an overpressure blast wave using a custom-built blast chamber. The effects of blast exposure on retina and optic nerve function and structure were evaluated using the pattern electroretinogram (pERG), spectral domain optical coherence tomography (OCT), and the chromatic pupil light reflex. Assessment of the pupil response to light demonstrated decreased maximum pupil constriction diameter in blast-injured mice using red light or blue light stimuli 24 hours after injury compared with baseline in the eye exposed to direct blast injury. A decrease in the pupil light reflex was not observed chronically following blast exposure. We observed a biphasic pERG decrease with the acute injury recovering by 24 hours postblast and the chronic injury appearing at 4 months postblast injury. Furthermore, at 3 months following injury, a significant decrease in the retinal nerve fiber layer was observed using OCT compared with controls. Histologic analysis of the retina and optic nerve revealed punctate regions of reduced cellularity in the ganglion cell layer and damage to optic nerves. Additionally, a significant upregulation of proteins associated with oxidative stress was observed acutely following blast exposure compared with control mice. Our study demonstrates that decrements in retinal ganglion cell responses can be detected after blast injury using noninvasive functional and structural tests. These objective responses may serve as surrogate tests for higher CNS functions following traumatic brain injury that are difficult to quantify.

Xenon Protects against Blast-Induced Traumatic Brain Injury in an In Vitro Model.

PubMed

Campos-Pires, Rita; Koziakova, Mariia; Yonis, Amina; Pau, Ashni; Macdonald, Warren; Harris, Katie; Edge, Christopher J; Franks, Nicholas P; Mahoney, Peter F; Dickinson, Robert

2018-04-15

The aim of this study was to evaluate the neuroprotective efficacy of the inert gas xenon as a treatment for patients with blast-induced traumatic brain injury in an in vitro laboratory model. We developed a novel blast traumatic brain injury model using C57BL/6N mouse organotypic hippocampal brain-slice cultures exposed to a single shockwave, with the resulting injury quantified using propidium iodide fluorescence. A shock tube blast generator was used to simulate open field explosive blast shockwaves, modeled by the Friedlander waveform. Exposure to blast shockwave resulted in significant (p < 0.01) injury that increased with peak-overpressure and impulse of the shockwave, and which exhibited a secondary injury development up to 72 h after trauma. Blast-induced propidium iodide fluorescence overlapped with cleaved caspase-3 immunofluorescence, indicating that shock-wave-induced cell death involves apoptosis. Xenon (50% atm) applied 1 h after blast exposure reduced injury 24 h (p < 0.01), 48 h (p < 0.05), and 72 h (p < 0.001) later, compared with untreated control injury. Xenon-treated injured slices were not significantly different from uninjured sham slices at 24 h and 72 h. We demonstrate for the first time that xenon treatment after blast traumatic brain injury reduces initial injury and prevents subsequent injury development in vitro. Our findings support the idea that xenon may be a potential first-line treatment for those with blast-induced traumatic brain injury.

Gun muzzle blast and flash

NASA Astrophysics Data System (ADS)

Klingenberg, Guenter; Heimerl, Joseph M.

A repository of fundamental experimental and analytical data concerning the complex phenomena associated with gun-muzzle blast and flash effects is presented, proceeding from gun muzzle signatures to modern gun-propulsion concepts, interior and transitional ballistics, and characterizations of blast-wave research and muzzle flash. Data are presented in support of a novel hypothesis which explains the ignition of secondary flash and elucidates the means for its suppression. Both chemical and mechanical (often competing) methods of flash suppression are treated. The historical work of Kesslau and Ladenburg is noted, together with French, British, Japanese and American research efforts and current techniques of experimental characterization for gun muzzle phenomena.

Comprehensive 3D Model of Shock Wave-Brain Interactions in Blast-Induced Traumatic Brain Injuries

DTIC Science & Technology

2009-10-01

waves can cause brain damage by other mechanisms including excess pressure (leading to contusions), excess strain (leading to subdural ... hematomas and/or diffuse axonal injuries), and, in particular, cavitation effects (leading to subcellular damage). This project aims at the development of a

Aluminum Micro-Balloons as Improved Fuel for Warhead Explosives

DTIC Science & Technology

2018-01-29

12-1-0006 Dr. Jerry W. Forbes Prepared by: Energetics Technology Center 10400 O Donnell Place Suite 202 St. Charles, MD 20603...the goal of enhancing blast waves. This 6.2 grant work provides the baseline technology to understand shock wave experiments done and to be done

Blast-Induced Acceleration in a Shock Tube: Distinguishing Primary and Tertiary Blast Injury

DTIC Science & Technology

2015-10-01

these well-defined exposure conditions, anesthetized rats are used to simultaneously record intracranial pressure (ICP), intravascular pressure , and...blast flow conditions (e.g. peak static and total pressure , positive phase duration, and impulse) and acceleration and displacement of a wide range of...resultant pressure responses in varied compartments in concert with the neuropathological, neurochemical, and neurobehavioral consequences of exposures

Blast injury research models

PubMed Central

Kirkman, E.; Watts, S.; Cooper, G.

2011-01-01

Blast injuries are an increasing problem in both military and civilian practice. Primary blast injury to the lungs (blast lung) is found in a clinically significant proportion of casualties from explosions even in an open environment, and in a high proportion of severely injured casualties following explosions in confined spaces. Blast casualties also commonly suffer secondary and tertiary blast injuries resulting in significant blood loss. The presence of hypoxaemia owing to blast lung complicates the process of fluid resuscitation. Consequently, prolonged hypotensive resuscitation was found to be incompatible with survival after combined blast lung and haemorrhage. This article describes studies addressing new forward resuscitation strategies involving a hybrid blood pressure profile (initially hypotensive followed later by normotensive resuscitation) and the use of supplemental oxygen to increase survival and reduce physiological deterioration during prolonged resuscitation. Surprisingly, hypertonic saline dextran was found to be inferior to normal saline after combined blast injury and haemorrhage. New strategies have therefore been developed to address the needs of blast-injured casualties and are likely to be particularly useful under circumstances of enforced delayed evacuation to surgical care. PMID:21149352

Brain Vulnerability to Repeated Blast Overpressure and Polytrauma

DTIC Science & Technology

2012-05-01

shock tube: distinguishing primary and tertiary blast injury mechanisms in rat TBI - Roles of polyunsaturated fatty acids in traumatic brain injury...vulnerabilities and resilience: evaluation of salutary effects of DHA supplementation using neurolipidomics and functional outcome assessments

Sub-lethal Ocular Trauma (SLOT): Establishing a Standardized Blast Threshold to Facilitate Diagnostic, Early Treatment, and Recovery Studies for Blast Injuries to the Eye and Optic Nerve

DTIC Science & Technology

2014-09-01

the less, we observed 64 a broad array of ocular injuries. Petras et al. (1997) observed a similar trend in rats exposed to overpressures of...2013. PMID: 22185582. Petras , J.M., Bauman, R.A., and Elsayed, N.M., 1997, Visual system degeneration induced by blast overpressure: Toxicology...2012, Primary blast injury to the eye and orbit: Finite element modeling: Investigative Ophthalmology: v. 53, pp. 8057–8066. Sanchez, R., Martin , R

Analysis of the Laser Propelled Lightcraft Vehicle

NASA Technical Reports Server (NTRS)

Feikema, Douglas

2000-01-01

Advanced propulsion research and technology require launch and space flight technologies, which can drastically reduce mission costs. Laser propulsion is a concept in which energy of a thrust producing reaction mass is supplied via beamed energy from an off-board power source. A variety of laser/beamed energy concepts were theoretically and experimentally investigated since the early 1970's. During the 1980's the Strategic Defense Initiative (SDI) research lead to the invention of the Laser Lightcraft concept. Based upon the Laser Lightcraft concept, the U.S. Air Force and NASA have jointly set out to develop technologies required for launching small payloads into Low Earth Orbit (LEO) for a cost of $1.0M or $1000/lb to $ 100/lb. The near term objectives are to demonstrate technologies and capabilities essential for a future earth to orbit launch capability. Laser propulsion offers the advantages of both high thrust and good specific impulse, I(sub sp), in excess of 1000 s. Other advantages are the simplicity and reliability of the engine because of few moving parts, simpler propellant feed system, and high specific impulse. Major limitations of this approach are the laser power available, absorption and distortion of the pulsed laser beam through the atmosphere, and coupling laser power into thrust throughout the flight envelope, The objective of this paper is to assist efforts towards optimizing the performance of the laser engine. In order to accomplish this goal (1) defocusing of the primary optic was investigated using optical ray tracing and (2), time dependent calculations were conducted of the optically induced blast wave to predict pressure and temperature in the vicinity of the cowl. Defocusing of the primary parabolic reflector causes blurring and reduction in the intensity of the laser ignition site on the cowl. However, because of the caustic effect of ray-tracing optics the laser radiation still forms a well-defined ignition line on the cowl. The blast wave calculations show reasonable agreement with previously published calculations and recent detailed CFD computations.

A Quick Look at Supernova 1987A

NASA Image and Video Library

2017-02-24

On February 24, 1987, astronomers in the southern hemisphere saw a supernova in the Large Magellanic Cloud. This new object was dubbed “Supernova 1987A” and was the brightest stellar explosion seen in over four centuries. Chandra has observed Supernova 1987A many times and the X-ray data reveal important information about this object. X-rays from Chandra have shown the expanding blast wave from the original explosion slamming into a ring of material expelled by the star before it exploded. The latest Chandra data reveal the blast wave has moved beyond the ring into a region that astronomers do not know much about. These observations can help astronomers learn how supernovas impact their environments and affect future generations of stars and planets.

Compact and reliable triggering method for near muzzle flash radiography

NASA Astrophysics Data System (ADS)

Lee, Eun S.; Hwang, Eul H.; Yim, Dong W.; Song, So Y.

1993-01-01

Precise timing for x-ray bursts is crucial in acquiring useful information from flash radiographic experiments. Triggering the flash x-ray system near the muzzle is a difficult task because of the intrinsic nature of the muzzle blast. In this work a compact and reliable triggering method for near muzzle flash radiography is introduced; a piezoelectric pin probe attached at the end of the barrel. These types of probes have not been activated by the precursor shock wave, but they have been activated by the main blast wave only. Reliability in triggering the flash x-ray system has been confirmed throughout a series of flash radiographic experiments near the muzzle for gun barrels with calibers up to 105 mm.

Modeling and simulation of explosion effectiveness as a function of blast and crowd characteristics

NASA Astrophysics Data System (ADS)

Usmani, Zeeshan-Ul-Hassan

Suicide bombing has become one of the most lethal and favorite modus operandi of terrorist organizations around the world. On average, there is a suicide bombing attack every six days somewhere in the world. While various attempts have been made to assess the impact of explosions on structures and military personnel, little has been done on modeling the impact of a blast wave on a crowd in civilian settings. The assessment of an explosion's effect on a crowd can lead to better management of disasters, triage of patients, locating blast victims under the debris, development of protective gear, and safe distance recommendations to reduce the casualties. The overall goal of this work is to predict the magnitude of injuries and lethality on humans from a blast-wave with various explosive and crowd characteristics, and to compare, contrast, and analyze the performance of explosive and injury models against the real-life data of suicide bombing incidents. This thesis introduces BlastSim---a physics based stationary multi-agent simulation platform to model and simulate a suicide bombing event. The agents are constrained by the physical characteristics and mechanics of the blast wave. The BlastSim is programmed to test, analyze, and validate the results of different model combinations under various conditions with different sets of parameters, such as the crowd and explosive characteristics, blockage and human shields, fragmentation and the bomber's position, in 2-dimensional and 3-dimensional environments. The suicide bombing event can be re-created for forensic analysis. The proposed model combinations show a significant performance---the Harold Brode explosive model with Catherine Lee injury model using the blockage stands out consistently to be the best with an overall cumulative accuracy of 87.6%. When comparing against actual data, overall, prediction accuracy can be increased by 71% using this model combination. The J. Clutter with Reflection explosive model using Charles Stewart injury model with blockage works best for confined-space incidents with an accuracy of 80%. Blockage in a crowd can increase the accuracy by 17% for all models. Line-of-sight with an attacker, rushing towards an exit, announcing the threat of a suicide bombing, sitting inside a vehicle or building, and standing closer to a wall or a rigid surface were found to be the most lethal choices both during and after an attack. The findings can have implications for emergency response and counter terrorism.

Transcriptional profiling in rat hair follicles following simulated Blast insult: a new diagnostic tool for traumatic brain injury.

PubMed

Zhang, Jing; Carnduff, Lisa; Norman, Grant; Josey, Tyson; Wang, Yushan; Sawyer, Thomas W; Martyniuk, Christopher J; Langlois, Valerie S

2014-01-01

With wide adoption of explosive-dependent weaponry during military activities, Blast-induced neurotrauma (BINT)-induced traumatic brain injury (TBI) has become a significant medical issue. Therefore, a robust and accessible biomarker system is in demand for effective and efficient TBI diagnosis. Such systems will also be beneficial to studies of TBI pathology. Here we propose the mammalian hair follicles as a potential candidate. An Advanced Blast Simulator (ABS) was developed to generate shock waves simulating traumatic conditions on brains of rat model. Microarray analysis was performed in hair follicles to identify the gene expression profiles that are associated with shock waves. Gene set enrichment analysis (GSEA) and sub-network enrichment analysis (SNEA) were used to identify cell processes and molecular signaling cascades affected by simulated bomb blasts. Enrichment analyses indicated that genes with altered expression levels were involved in central nervous system (CNS)/peripheral nervous system (PNS) responses as well as signal transduction including Ca2+, K+-transportation-dependent signaling, Toll-Like Receptor (TLR) signaling and Mitogen Activated Protein Kinase (MAPK) signaling cascades. Many of the pathways identified as affected by shock waves in the hair follicles have been previously reported to be TBI responsive in other organs such as brain and blood. The results suggest that the hair follicle has some common TBI responsive molecular signatures to other tissues. Moreover, various TBI-associated diseases were identified as preferentially affected using a gene network approach, indicating that the hair follicle may be capable of reflecting comprehensive responses to TBI conditions. Accordingly, the present study demonstrates that the hair follicle is a potentially viable system for rapid and non-invasive TBI diagnosis.

Transcriptional Profiling in Rat Hair Follicles following Simulated Blast Insult: A New Diagnostic Tool for Traumatic Brain Injury

PubMed Central

Zhang, Jing; Carnduff, Lisa; Norman, Grant; Josey, Tyson; Wang, Yushan; Sawyer, Thomas W.; Martyniuk, Christopher J.; Langlois, Valerie S.

2014-01-01

With wide adoption of explosive-dependent weaponry during military activities, Blast-induced neurotrauma (BINT)-induced traumatic brain injury (TBI) has become a significant medical issue. Therefore, a robust and accessible biomarker system is in demand for effective and efficient TBI diagnosis. Such systems will also be beneficial to studies of TBI pathology. Here we propose the mammalian hair follicles as a potential candidate. An Advanced Blast Simulator (ABS) was developed to generate shock waves simulating traumatic conditions on brains of rat model. Microarray analysis was performed in hair follicles to identify the gene expression profiles that are associated with shock waves. Gene set enrichment analysis (GSEA) and sub-network enrichment analysis (SNEA) were used to identify cell processes and molecular signaling cascades affected by simulated bomb blasts. Enrichment analyses indicated that genes with altered expression levels were involved in central nervous system (CNS)/peripheral nervous system (PNS) responses as well as signal transduction including Ca2+, K+-transportation-dependent signaling, Toll-Like Receptor (TLR) signaling and Mitogen Activated Protein Kinase (MAPK) signaling cascades. Many of the pathways identified as affected by shock waves in the hair follicles have been previously reported to be TBI responsive in other organs such as brain and blood. The results suggest that the hair follicle has some common TBI responsive molecular signatures to other tissues. Moreover, various TBI-associated diseases were identified as preferentially affected using a gene network approach, indicating that the hair follicle may be capable of reflecting comprehensive responses to TBI conditions. Accordingly, the present study demonstrates that the hair follicle is a potentially viable system for rapid and non-invasive TBI diagnosis. PMID:25136963

Origin of asymmetries in X-ray emission lines from the blast wave of the 2014 outburst of nova V745 Sco

NASA Astrophysics Data System (ADS)

Orlando, Salvatore; Drake, Jeremy J.; Miceli, Marco

2017-02-01

The symbiotic nova V745 Sco was observed in outburst on 2014 February 6. Its observations by the Chandra X-ray Observatory at days 16 and 17 have revealed a spectrum characterized by asymmetric and blueshifted emission lines. Here we investigate the origin of these asymmetries through 3D hydrodynamic simulations describing the outburst during the first 20 d of evolution. The model takes into account thermal conduction and radiative cooling, and assumes that a blast wave propagates through an equatorial density enhancement (EDE). From these simulations, we synthesize the X-ray emission and derive the spectra as they would be observed with Chandra. We find that both the blast wave and the ejecta distribution are efficiently collimated in polar directions due to the presence of the EDE. The majority of the X-ray emission originates from the interaction of the blast with the EDE and is concentrated on the equatorial plane as a ring-like structure. Our `best-fitting' model requires a mass of ejecta in the outburst Mej ≈ 3 × 10-7 M⊙ and an explosion energy Eb ≈ 3 × 1043 erg, and reproduces the distribution of emission measure versus temperature and the evolution of shock velocity and temperature inferred from the observations. The model predicts asymmetric and blueshifted line profiles similar to those observed and explains their origin as due to substantial X-ray absorption of redshifted emission by ejecta material. The comparison of predicted and observed Ne and O spectral line ratios reveals no signs of strong Ne enhancement and suggests that the progenitor is a CO white dwarf.

Ground vibration monitoring for construction blasting in urban areas.

DOT National Transportation Integrated Search

2001-04-01

The primary objectives of this study were to determine a recommendation for the preblast : area for surveys, and to obtain actual field vibrations from rock blasting : operations, in populated regions within specific geologic units. The area confined...

Tympanic membrane perforation after combat blast exposure in Iraq: a poor biomarker of primary blast injury.

PubMed

Harrison, Corey D; Bebarta, Vikhyat S; Grant, Gerald A

2009-07-01

The US military has reported over 10,000 improvised explosive device attacks attributing to over 400 deaths in Iraq in 2005. Otologic blast injury and tympanic membrane (TM) perforation have traditionally been used as a predictor, or biomarker, of serious or occult primary blast injury (PBI). Although combat injuries from the US-Iraq conflict have been described, the utility of TM perforation as a marker of PBI has not. The objective of this study is to determine the incidence of tympanic perforation in patients subject to blast exposures and describe its utility as a biomarker of more serious primary barotrauma, as observed at a US military hospital in Iraq. In our institutional review board-approved study, all patients during a 30-day period who arrived at a tertiary US military hospital in Iraq were evaluated. All patients with blast injures were identified on arrival to the hospital emergency department and were followed up through their hospital course and evacuation to the United States to assure they received proper otolaryngology evaluation and follow-up. Demographic data and manifestations of PBI (TM perforation, pneumothorax, pulmonary contusion, nonpenetrating facial sinus injury, and bowel perforation) and other combat injuries were recorded. The diagnostic tests and clinical examination findings used to identify these complications were also recorded. One hundred sixty-seven patients were enrolled over 30 days. All blast exposures resulted from primary or secondary explosions from munitions used in combat. This included both combatants and civilians. All patients were men. The mean patient age was 28 years (range, 12-55 years). Sixteen percent (27 of 167) of blast-exposed patients had TM perforation. Thirteen of 27 patients with perforations had bilateral perforations. Twelve of 167 patients (7%) had PBI. Six of 12 patients (50%) with PBI had TM perforation. The use of TM perforation as a biomarker for PBI resulted in a sensitivity of 50% (95% CI, 22-78%) and specificity of 87% (95% CI, 81-92%). Both TM perforation and PBI are rare with improvised explosive devices and other explosive devices in the current Iraqi-US conflict. Contrary to previous belief and management guidelines, TM perforation had low sensitivity for serious or occult PBI and was not a good biomarker. On the basis of the findings of this study, the absence of TM perforation does not appear to exclude other serious PBI.

Dynamic load mitigation using dissipative elastic metamaterials with multiple Maxwell-type oscillators

NASA Astrophysics Data System (ADS)

Alamri, Sagr; Li, Bing; Tan, K. T.

2018-03-01

Dissipative elastic metamaterials have attracted increased attention in recent times. This paper presents the development of a dissipative elastic metamaterial with multiple Maxwell-type resonators for stress wave attenuation. The mechanism of the dissipation effect on the vibration characteristics is systematically investigated by mass-spring-damper models with single and dual resonators. Based on the parameter optimization, it is revealed that a broadband wave attenuation region (stopping band) can be obtained by properly utilizing interactions from resonant motions and viscoelastic effects of the Maxwell-type oscillators. The relevant numerical verifications are conducted for various cases, and excellent agreement between the numerical and theoretical frequency response functions is shown. The design of this dissipative metamaterial system is further applied for dynamic load mitigation and blast wave attenuation. Moreover, the transient response in the continuum model is designed and analyzed for more robust design. By virtue of the bandgap merging effect induced by the Maxwell-type damper, the transient blast wave can be almost completely suppressed in the low frequency range. A significantly improved performance of the proposed dissipative metamaterials for stress wave mitigation is verified in both time and frequency domains.

Bomb blast imaging: bringing order to chaos.

PubMed

Dick, E A; Ballard, M; Alwan-Walker, H; Kashef, E; Batrick, N; Hettiaratchy, S; Moran, C G

2018-06-01

Blast injuries are complex, severe, and outside of our everyday clinical practice, but every radiologist needs to understand them. By their nature, bomb blasts are unpredictable and affect multiple victims, yet require an immediate, coordinated, and whole-hearted response from all members of the clinical team, including all radiology staff. This article will help you gain the requisite expertise in blast imaging including recognising primary, secondary, and tertiary blast injuries. It will also help you understand the fundamental role that imaging plays during mass casualty attacks and how to avoid radiology becoming a bottleneck to the forward flow of severely injured patients as they are triaged and treated. Copyright © 2018. Published by Elsevier Ltd.

Combined Effects of Primary and Tertiary Blast on Rat Brain: Characterization of a Model of Blast-induced Mild Traumatic Brain Injury

DTIC Science & Technology

2012-03-01

blast injury mechanisms in rat TBI - Roles of polyunsaturated fatty acids in traumatic brain injury vulnerabilities and resilience: evaluation of...salutary effects of DHA supplementation using neurolipidomics and functional outcome assessments - Diagnostic and Therapeutic Targeting of...immunohistochemical assessments reveal greater glial fibrillary acidic protein (GFAP) and IBa1 immunoreactivity in rats subjected to combined injuries than are

Molecular Signatures and Diagnostic Biomarkers of Cumulative, Blast-Graded Mild TBI

DTIC Science & Technology

2013-10-01

Kirk, Department of Mechanical and Aerospace Engineering, Florida Institute of Technology, Melbourne FL 32901 January 3 rd , 2013 2. Prima V...induced Neurotrauma “Neuro-glial and systemic mechanisms of pathological responses in rat models of primary blast overpressure compared to "composite...inflammation biomarkers such as L-selectin and s-ICAM involved in molecular mechanisms of blast-induced injury. The FIT prototype sensor (version 1) to

Retinal Ganglion Cell Damage in an Experimental Rodent Model of Blast-Mediated Traumatic Brain Injury

PubMed Central

Mohan, Kabhilan; Kecova, Helga; Hernandez-Merino, Elena; Kardon, Randy H.; Harper, Matthew M.

2013-01-01

Purpose. To evaluate retina and optic nerve damage following experimental blast injury. Methods. Healthy adult mice were exposed to an overpressure blast wave using a custom-built blast chamber. The effects of blast exposure on retina and optic nerve function and structure were evaluated using the pattern electroretinogram (pERG), spectral domain optical coherence tomography (OCT), and the chromatic pupil light reflex. Results. Assessment of the pupil response to light demonstrated decreased maximum pupil constriction diameter in blast-injured mice using red light or blue light stimuli 24 hours after injury compared with baseline in the eye exposed to direct blast injury. A decrease in the pupil light reflex was not observed chronically following blast exposure. We observed a biphasic pERG decrease with the acute injury recovering by 24 hours postblast and the chronic injury appearing at 4 months postblast injury. Furthermore, at 3 months following injury, a significant decrease in the retinal nerve fiber layer was observed using OCT compared with controls. Histologic analysis of the retina and optic nerve revealed punctate regions of reduced cellularity in the ganglion cell layer and damage to optic nerves. Additionally, a significant upregulation of proteins associated with oxidative stress was observed acutely following blast exposure compared with control mice. Conclusions. Our study demonstrates that decrements in retinal ganglion cell responses can be detected after blast injury using noninvasive functional and structural tests. These objective responses may serve as surrogate tests for higher CNS functions following traumatic brain injury that are difficult to quantify. PMID:23620426

Current topics in shock waves; Proceedings of the International Symposium on Shock Waves and Shock Tubes, 17th, Lehigh University, Bethlehem, PA, July 17-21, 1989

NASA Astrophysics Data System (ADS)

Kim, Yong W.

Various papers on shock waves are presented. The general topics addressed include: shock formation, focusing, and implosion; shock reflection and diffraction; turbulence; laser-produced plasmas and waves; ionization and shock-plasma interaction; chemical kinetics, pyrolysis, and soot formation; experimental facilities, techniques, and applications; ignition of detonation and combustion; particle entrainment and shock propagation through particle suspension; boundary layers and blast simulation; computational methods and numerical simulation.

Radiative precursors driven by converging blast waves in noble gases

DOE Office of Scientific and Technical Information (OSTI.GOV)

Burdiak, G. C.; Lebedev, S. V.; Harvey-Thompson, A. J.

2014-03-15

A detailed study of the radiative precursor that develops ahead of converging blast waves in gas-filled cylindrical liner z-pinch experiments is presented. The experiment is capable of magnetically driving 20 km s{sup −1} blast waves through gases of densities of the order 10{sup −5} g cm{sup −3} (see Burdiak et al. [High Energy Density Phys. 9(1), 52–62 (2013)] for a thorough description). Data were collected for Ne, Ar, and Xe gas-fills. The geometry of the setup allows a determination of the plasma parameters both in the precursor and across the shock, along a nominally uniform line of sight that is perpendicularmore » to the propagation of the shock waves. Radiation from the shock was able to excite NeI, ArII, and XeII/XeIII precursor spectral features. It is shown that the combination of interferometry and optical spectroscopy data is inconsistent with upstream plasmas being in LTE. Specifically, electron density gradients do not correspond to any apparent temperature change in the emission spectra. Experimental data are compared to 1D radiation hydrodynamics HELIOS-CR simulations and to PrismSPECT atomic physics calculations to assist in a physical interpretation of the observations. We show that upstream plasma is likely in the process of being radiatively heated and that the emission from a small percentage of ionised atoms within a cool background plasma dominates the emission spectra. Experiments were carried out on the MAGPIE and COBRA pulsed-power facilities at Imperial College London and Cornell University, respectively.« less

Head orientation affects the intracranial pressure response resulting from shock wave loading in the rat.

PubMed

Dal Cengio Leonardi, Alessandra; Keane, Nickolas J; Bir, Cynthia A; Ryan, Anne G; Xu, Liaosa; Vandevord, Pamela J

2012-10-11

Since an increasing number of returning military personnel are presenting with neurological manifestations of traumatic brain injury (TBI), there has been a great focus on the effects resulting from blast exposure. It is paramount to resolve the physical mechanism by which the critical stress is being inflicted on brain tissue from blast wave encounters with the head. This study quantitatively measured the effect of head orientation on intracranial pressure (ICP) of rats exposed to a shock wave. Furthermore, the study examined how skull maturity affects ICP response of animals exposed to shock waves at various orientations. Results showed a significant increase in ICP values in larger rats at any orientation. Furthermore, when side-ICP values were compared to the other orientations, the peak pressures were significantly lower suggesting a relation between ICP and orientation of the head due to geometry of the skull and location of sutures. This finding accentuates the importance of skull dynamics in explaining possible injury mechanisms during blast. Also, the rate of pressure change was measured and indicated that the rate was significantly higher when the top of the head was facing the shock front. The results confirm that the biomechanical response of the superior rat skull is distinctive compared to other areas of the skull, suggesting a skull flexure mechanism. These results not only present insights into the mechanism of brain injury, but also provide information which can be used for designing more effective protective head gear. Copyright © 2012 Elsevier Ltd. All rights reserved.

Protection of the lung from blast overpressure by stress wave decouplers, buffer plates or sandwich panels.

PubMed

Sedman, Andrew; Hepper, A

2018-03-19

This paper outlines aspects of UK Ministry of Defence's research and development of blast overpressure protection technologies appropriate for use in body armour, with the aim of both propagating new knowledge and updating existing information. Two simple models are introduced not only to focus the description of the mechanism by which the lungs can be protected, but also to provide a bridge between fields of research that may hold the key to further advances in protection technology and related body armour. Protection can be provided to the lungs by decoupling the stress wave transmission into the thorax by managing the blast energy imparted through the protection system. It is proposed that the utility of the existing 'simple decoupler' blast overpressure protection is reviewed in light of recent developments in the treatment of those sustaining both overpressure and fragment injuries. It is anticipated that further advances in protection technology may be generated by those working in other fields on the analogous technologies of 'buffer plates' and 'sandwich panels'. © Crown copyright (2018), Dstl. This material is licensed under the terms of the Open Government Licence except where otherwise stated. To view this licence, visit http://www.nationalarchives.gov.uk/doc/open-government-licence/version/3 or write to the Information Policy Team, The National Archives, Kew, London TW9 4DU, or email: psi@nationalarchives.gsi.gov.uk.

Imaging features of blast injuries: experience from 2015 Ankara bombing in Turkey.

PubMed

Yazgan, Cisel; Aksu, Nalan M

2016-06-01

To present the radiological features of blast-related injuries in the victims of the 10 October 2015 Ankara bombing and emphasize the importance of imaging. This retrospective descriptive study included a total of 28 patients who underwent CT scan or radiographic imaging within 6 h after the bombing on 10 October 2015. CT scans and plain radiographs were evaluated regarding mechanisms of injuries. Injuries were categorized as primary, secondary, tertiary and quaternary. The number of shrapnel and distribution of injuries were noted. Injury Severity Score (ISS) was used to rank the severity of the injury. Primary blast injuries consisted of only tympanic membrane rupture. A high rate of patients (21/28 patients) in the study group suffered from secondary blast injuries. Tertiary injuries were detected in only three patients. Of the severely injured patients, five had abdominal injuries, three had thoracic injuries and six had extremity injuries. ISS was significantly higher in patients with thoracic and abdominal injuries. Our results after the suicide bomb attacks showed that the most common injury pattern was secondary blast injury. The torso was the most commonly injured body region, followed by the extremities. This specific injury pattern requires the use of immense radiological imaging. Hence, radiologists should be aware of the mechanisms and spectrums of blast-related injuries. Both the unique injury pattern and the following chaos make blast-related injuries a challenge in terms of triage, diagnosis and management. Radiologists should be familiar with the wide spectrum of these unique injuries.

AN EXTERNAL SHOCK ORIGIN OF GRB 141028A

DOE Office of Scientific and Technical Information (OSTI.GOV)

Burgess, J. Michael; Bégué, Damien; Ryde, Felix

The prompt emission of the long, smooth, and single-pulsed gamma-ray burst, GRB 141028A, is analyzed under the guise of an external shock model. First, we fit the γ -ray spectrum with a two-component photon model, namely, synchrotron+blackbody, and then fit the recovered evolution of the synchrotron νF{sub ν} peak to an analytic model derived considering the emission of a relativistic blast wave expanding into an external medium. The prediction of the model for the νF{sub ν} peak evolution matches well with the observations. We observe the blast wave transitioning into the deceleration phase. Furthermore, we assume the expansion of themore » blast wave to be nearly adiabatic, motivated by the low magnetic field deduced from the observations. This allows us to recover within an order of magnitude the flux density at the νF{sub ν} peak, which is remarkable considering the simplicity of the analytic model. Under this scenario we argue that the distinction between prompt and afterglow emission is superfluous as both early-time emission and late-time emission emanate from the same source. While the external shock model is clearly not a universal solution, this analysis opens the possibility that at least some fraction of GRBs can be explained with an external shock origin of their prompt phase.« less

Initiation and structures of gaseous detonation

NASA Astrophysics Data System (ADS)

Vasil'ev, A. A.; Vasiliev, V. A.

2018-03-01

The analysis of the initiation of a detonation wave (DW) and the emergence of a multi-front structure of the DW-front are presented. It is shown that the structure of the DW arises spontaneously at the stage of a strong overdriven of the wave. The hypothesis of the gradual enhancement of small perturbations on an initially smooth initiating blast wave, traditionally used in the numerical simulation of multi-front detonation, does not agree with the experimental data. The instability of the DW is due to the chemical energy release of the combustible mixture Q. A technique for determining the Q-value of mixture was proposed, based on reconstruction of the trajectory of the expanding wave from the position of the strong explosion model. The wave trajectory at the critical initiation of a multifront detonation in a combustible mixture is compared with the trajectory of an explosive wave from the same initiator in an inert mixture whose gas-dynamic parameters are equivalent to the parameters of the combustible mixture. The energy release of a mixture is defined as the difference in the joint energy release of the initiator and the fuel mixture during the critical initiation and energy release of the initiator when the blast wave is excited in an inert mixture. Observable deviations of the experimental profile of Q from existing model representations were found.

Comparison of Some Blast Vibration Predictors for Blasting in Underground Drifts and Some Observations

NASA Astrophysics Data System (ADS)

Bhagwat, Vaibhab Pramod; Dey, Kaushik

2016-04-01

Drilling and blasting are the most economical excavation techniques in underground drifts driven through hard rock formation. Burn cut is the most popular drill pattern, used in this case, to achieve longer advance per blast round. The ground vibration generated due to the propagation of blast waves on the detonation of explosive during blasting is the principal cause for structural and rock damage. Thus, ground vibration is a point of concern for the blasting engineers. The ground vibration from a blast is measured using a seismograph placed at the blast monitoring station. The measured vibrations, in terms of peak particle velocity, are related to the maximum charge detonated at one instant and the distance of seismograph from the blast point. The ground vibrations from a number of blast rounds of varying charge/delay and distances are monitored. A number of scaling factors of these dependencies (viz. Distance and maximum charge/delay) have been proposed by different researchers, namely, square root, cube root, CMRI, Langefors and Kihlstrom, Ghosh-Daemon, Indian standard etc. Scaling factors of desired type are computed for all the measured blast rounds. Regression analysis is carried out between the scaling factors and peak particle velocities to establish the coefficients of the vibration predictor equation. Then, the developed predictor equation is used for designing the blast henceforth. Director General of Mine Safety, India, specified that ground vibrations from eight to ten blast rounds of varying charge/delay and distances should be monitored to develop a predictor equation; however, there is no guideline about the type of scaling factor to be used. Further to this, from the statistical point of view, a regression analysis on a small sample population cannot be accepted without the testing of hypothesis. To show the importance of the above, in this paper, seven scaling factors are considered for blast data set of a hard-rock underground drift using burn-cut blast design. The possible step by step approach to establish a vibration predictor equation is also proposed.

In Vitro Studies of Primary Explosive Blast Loading on Neurons

DTIC Science & Technology

2015-09-01

blast but was significantly higher for the triple blast. Membrane permeability was also evaluated by calcein dye . Calcein is normally a membrane...impermeable dye ; however, upon damage to the plasma membrane, leakage of the dye into the cytosol can occur, causing an increase in the fluorescence of the...intensities were significantly higher for the injured cells compared with the control and sham. However, the difference in dye uptake between the singly and

Blast-Induced Acceleration in a Shock Tube: Distinguishing Primary and Tertiary Blast Injury

DTIC Science & Technology

2016-10-01

objects of varied areal densities to define relations of blast flow conditions to acceleration and displacement , we have begun examination of the effects... displacement from other biomechanical components and effects of the shockwave. 15. SUBJECT TERMS Key words or phrases identifying major concepts in the...and total pressure, positive phase duration, and impulse) and acceleration and displacement of a wide range of inanimate objects, we have continued

Establishment of segment polarity in the ectoderm of the leech Helobdella

NASA Technical Reports Server (NTRS)

Seaver, E. C.; Shankland, M.

2001-01-01

The segmented ectoderm and mesoderm of the leech arise via a stereotyped cell lineage from embryonic stem cells called teloblasts. Each teloblast gives rise to a column of primary blast cell daughters, and the blast cells generate descendant clones that serve as the segmental repeats of their particular teloblast lineage. We have examined the mechanism by which the leech primary blast cell clones acquire segment polarity - i.e. a fixed sequence of positional values ordered along the anteroposterior axis of the segmental repeat. In the O and P teloblast lineages, the earliest divisions of the primary blast cell segregate anterior and posterior cell fates along the anteroposterior axis. Using a laser microbeam, we ablated single cells from both o and p blast cell clones at stages when the clone was two to four cells in length. The developmental fate of the remaining cells was characterized with rhodamine-dextran lineage tracer. Twelve different progeny cells were ablated, and in every case the ablation eliminated the normal descendants of the ablated cell while having little or no detectable effect on the developmental fate of the remaining cells. This included experiments in which we specifically ablated those blast cell progeny that are known to express the engrailed gene, or their lineal precursors. These findings confirm and extend a previous study by showing that the establishment of segment polarity in the leech ectoderm is largely independent of cell interactions conveyed along the anteroposterior axis. Both intercellular signaling and engrailed expression play an important role in the segment polarity specification of the Drosophila embryo, and our findings suggest that there may be little or no conservation of this developmental mechanism between those two organisms.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Suzuki, Akihiro; Maeda, Keiichi; Shigeyama, Toshikazu

A two-dimensional special relativistic radiation-hydrodynamics code is developed and applied to numerical simulations of supernova shock breakout in bipolar explosions of a blue supergiant. Our calculations successfully simulate the dynamical evolution of a blast wave in the star and its emergence from the surface. Results of the model with spherical energy deposition show a good agreement with previous simulations. Furthermore, we calculate several models with bipolar energy deposition and compare their results with the spherically symmetric model. The bolometric light curves of the shock breakout emission are calculated by a ray-tracing method. Our radiation-hydrodynamic models indicate that the early partmore » of the shock breakout emission can be used to probe the geometry of the blast wave produced as a result of the gravitational collapse of the iron core.« less

The Sedov Blast Wave as a Radial Piston Verification Test

DOE PAGES

Pederson, Clark; Brown, Bart; Morgan, Nathaniel

2016-06-22

The Sedov blast wave is of great utility as a verification problem for hydrodynamic methods. The typical implementation uses an energized cell of finite dimensions to represent the energy point source. We avoid this approximation by directly finding the effects of the energy source as a boundary condition (BC). Furthermore, the proposed method transforms the Sedov problem into an outward moving radial piston problem with a time-varying velocity. A portion of the mesh adjacent to the origin is removed and the boundaries of this hole are forced with the velocities from the Sedov solution. This verification test is implemented onmore » two types of meshes, and convergence is shown. Our results from the typical initial condition (IC) method and the new BC method are compared.« less

The state of clouds in a violent interstellar medium

NASA Astrophysics Data System (ADS)

Heathcote, S. R.; Brand, P. W. J. L.

1983-04-01

A highly approximate but simple model is developed which describes the interaction of a supernova blast wave with an interstellar cloud. The behavior of a cloud when exposed to conditions prevalent in a violent interstellar medium is examined using this model. Results show that after a cloud has been shocked it is rarely allowed sufficient time to return to pressure equilibrium with its surroundings before encountering a second shock. Thus, significant departures from pressure equilibrium are inevitable. It is determined that the disruption of a cloud by its passage through a blast wave is quite effective and the half life of clouds cannot greatly exceed the mean interval between shocks striking a given cloud. In addition, it is found that composite core-envelope clouds are not viable under typical conditions.

Waveform inversion of acoustic waves for explosion yield estimation

DOE PAGES

Kim, K.; Rodgers, A. J.

2016-07-08

We present a new waveform inversion technique to estimate the energy of near-surface explosions using atmospheric acoustic waves. Conventional methods often employ air blast models based on a homogeneous atmosphere, where the acoustic wave propagation effects (e.g., refraction and diffraction) are not taken into account, and therefore, their accuracy decreases with increasing source-receiver distance. In this study, three-dimensional acoustic simulations are performed with a finite difference method in realistic atmospheres and topography, and the modeled acoustic Green's functions are incorporated into the waveform inversion for the acoustic source time functions. The strength of the acoustic source is related to explosionmore » yield based on a standard air blast model. The technique was applied to local explosions (<10 km) and provided reasonable yield estimates (<~30% error) in the presence of realistic topography and atmospheric structure. In conclusion, the presented method can be extended to explosions recorded at far distance provided proper meteorological specifications.« less

Cellular characterization of compression-induceddamage in live biological samples

NASA Astrophysics Data System (ADS)

Bo, Chiara; Balzer, Jens; Hahnel, Mark; Rankin, Sara M.; Brown, Katherine A.; Proud, William

2012-03-01

Understanding the damage that high intensity compression waves induce in human tissues is critical for developing improved therapies for patients suffering from blast injuries. Experimentally based models of blast injury using live biological samples are needed. In this study we have developed a system to directly assess the effects of dynamic loading conditions on live cells. Here, we describe a confinement chamber designed to subject live cell cultures in a liquid environment to high intensity compression waves using a split Hopkinson pressure bar system. Signals from the strain gauges mounted on the bars and the chamber allow the measurement of parameters such as pressure and duration of the stimulus. The chamber itself also allows recovery of cells subjected to compression for assessment of cellular damage. In these studies we present evidence of increased levels of damage and loss of cellular integrity in cultured mouse mesenchymal stem cells subjected to a high-intensity compression wave with a peak pressure of 7.6 ± 0.8 MPa.

Waveform inversion of acoustic waves for explosion yield estimation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kim, K.; Rodgers, A. J.

We present a new waveform inversion technique to estimate the energy of near-surface explosions using atmospheric acoustic waves. Conventional methods often employ air blast models based on a homogeneous atmosphere, where the acoustic wave propagation effects (e.g., refraction and diffraction) are not taken into account, and therefore, their accuracy decreases with increasing source-receiver distance. In this study, three-dimensional acoustic simulations are performed with a finite difference method in realistic atmospheres and topography, and the modeled acoustic Green's functions are incorporated into the waveform inversion for the acoustic source time functions. The strength of the acoustic source is related to explosionmore » yield based on a standard air blast model. The technique was applied to local explosions (<10 km) and provided reasonable yield estimates (<~30% error) in the presence of realistic topography and atmospheric structure. In conclusion, the presented method can be extended to explosions recorded at far distance provided proper meteorological specifications.« less

Modeling of weak blast wave propagation in the lung.

PubMed

D'yachenko, A I; Manyuhina, O V

2006-01-01

Blast injuries of the lung are the most life-threatening after an explosion. The choice of physical parameters responsible for trauma is important to understand its mechanism. We developed a one-dimensional linear model of an elastic wave propagation in foam-like pulmonary parenchyma to identify the possible cause of edema due to the impact load. The model demonstrates different injury localizations for free and rigid boundary conditions. The following parameters were considered: strain, velocity, pressure in the medium and stresses in structural elements, energy dissipation, parameter of viscous criterion. Maximum underpressure is the most suitable wave parameter to be the criterion for edema formation in a rabbit lung. We supposed that observed scattering of experimental data on edema severity is induced by the physiological variety of rabbit lungs. The criterion and the model explain this scattering. The model outlines the demands for experimental data to make an unambiguous choice of physical parameters responsible for lung trauma due to impact load.

Reactive Blast Waves from Composite Charges

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kuhl, A L; Bell, J B; Beckner, V E

2009-10-16

Investigated here is the performance of composite explosives - measured in terms of the blast wave they drive into the surrounding environment. The composite charge configuration studied here was a spherical booster (1/3 charge mass), surrounded by aluminum (Al) powder (2/3 charge mass) at an initial density of {rho}{sub 0} = 0.604 g/cc. The Al powder acts as a fuel but does not detonate - thereby providing an extreme example of a 'non-ideal' explosive (where 2/3 of the charge does not detonate). Detonation of the booster charge creates a blast wave that disperses the Al powder and ignites the ensuingmore » Al-air mixture - thereby forming a two-phase combustion cloud embedded in the explosion. Afterburning of the booster detonation products with air also enhances and promotes the Al-air combustion process. Pressure waves from such reactive blast waves have been measured in bomb calorimeter experiments. Here we describe numerical simulations of those experiments. A Heterogeneous Continuum Model was used to model the dispersion and combustion of the Al particle cloud. It combines the gasdynamic conservation laws for the gas phase with a dilute continuum model for the dispersed phase, as formulated by Nigmatulin. Inter-phase mass, momentum and energy exchange are prescribed by phenomenological models of Khasainov. It incorporates a combustion model based on mass conservation laws for fuel, air and products; source/sink terms are treated in the fast-chemistry limit appropriate for such gasdynamic fields, along with a model for mass transfer from the particle phase to the gas. The model takes into account both the afterburning of the detonation products of the booster with air, and the combustion of the Al particles with air. The model equations were integrated by high-order Godunov schemes for both the gas and particle phases. Adaptive Mesh Refinement (AMR) was used to capture the energy-bearing scales of the turbulent flow on the computational grid, and to track/resolve reaction zones. Numerical simulations of the explosion fields from 1.5-g and 10-kg composite charges were performed. Computed pressure histories (red curve) are compared with measured waveforms (black curves) in Fig. 1. Comparison of these results with a waveform for a non-combustion case in nitrogen (blue curve) demonstrates that a reactive blast wave was formed. Cross-sectional views of the temperature field at various times are presented in Fig. 2, which shows that the flow is turbulent. Initially, combustion occurs at the fuel-air interface, and the energy release rate is controlled by the rate of turbulent mixing. Eventually, oxidizer becomes distributed throughout the cloud via ballistic mixing of the particles with air; energy release then occurs in a distributed combustion mode, and Al particle kinetics controls the energy release rate. Details of the Heterogeneous Continuum Model and results of the numerical simulations of composite charge explosions will be described in the paper.« less

Mechanical damage of tympanic membrane in relation to impulse pressure waveform - A study in chinchillas.

PubMed

Gan, Rong Z; Nakmali, Don; Ji, Xiao D; Leckness, Kegan; Yokell, Zachary

2016-10-01

Mechanical damage to middle ear components in blast exposure directly causes hearing loss, and the rupture of the tympanic membrane (TM) is the most frequent injury of the ear. However, it is unclear how the severity of injury graded by different patterns of TM rupture is related to the overpressure waveforms induced by blast waves. In the present study, the relationship between the TM rupture threshold and the impulse or overpressure waveform has been investigated in chinchillas. Two groups of animals were exposed to blast overpressure simulated in our lab under two conditions: open field and shielded with a stainless steel cup covering the animal head. Auditory brainstem response (ABR) and wideband tympanometry were measured before and after exposure to check the hearing threshold and middle ear function. Results show that waveforms recorded in the shielded case were different from those in the open field and the TM rupture threshold in the shielded case was lower than that in the open field (3.4 ± 0.7 vs. 9.1 ± 1.7 psi or 181 ± 1.6 vs. 190 ± 1.9 dB SPL). The impulse pressure energy spectra analysis of waveforms demonstrates that the shielded waveforms include greater energy at high frequencies than that of the open field waves. Finally, a 3D finite element (FE) model of the chinchilla ear was used to compute the distributions of stress in the TM and the TM displacement with impulse pressure waves. The FE model-derived change of stress in response to pressure loading in the shielded case was substantially faster than that in the open case. This finding provides the biomechanical mechanisms for blast induced TM damage in relation to overpressure waveforms. The TM rupture threshold difference between the open and shielded cases suggests that an acoustic role of helmets may exist, intensifying ear injury during blast exposure. Copyright © 2016 Elsevier B.V. All rights reserved.

Detection of Blast-Related Traumatic Brain Injury in U.S. Military Personnel

PubMed Central

Mac Donald, Christine L.; Johnson, Ann M.; Cooper, Dana; Nelson, Elliot C.; Werner, Nicole J.; Shimony, Joshua S.; Snyder, Abraham Z.; Raichle, Marcus E.; Witherow, John R.; Fang, Raymond; Flaherty, Stephen F.; Brody, David L.

2011-01-01

BACKGROUND Blast-related traumatic brain injuries have been common in the Iraq and Afghanistan wars, but fundamental questions about the nature of these injuries remain unanswered. METHODS We tested the hypothesis that blast-related traumatic brain injury causes traumatic axonal injury, using diffusion tensor imaging (DTI), an advanced form of magnetic resonance imaging that is sensitive to axonal injury. The subjects were 63 U.S. military personnel who had a clinical diagnosis of mild, uncomplicated traumatic brain injury. They were evacuated from the field to the Landstuhl Regional Medical Center in Landstuhl, Germany, where they underwent DTI scanning within 90 days after the injury. All the subjects had primary blast exposure plus another, blast-related mechanism of injury (e.g., being struck by a blunt object or injured in a fall or motor vehicle crash). Controls consisted of 21 military personnel who had blast exposure and other injuries but no clinical diagnosis of traumatic brain injury. RESULTS Abnormalities revealed on DTI were consistent with traumatic axonal injury in many of the subjects with traumatic brain injury. None had detectible intracranial injury on computed tomography. As compared with DTI scans in controls, the scans in the subjects with traumatic brain injury showed marked abnormalities in the middle cerebellar peduncles (P<0.001), in cingulum bundles (P = 0.002), and in the right orbitofrontal white matter (P = 0.007). In 18 of the 63 subjects with traumatic brain injury, a significantly greater number of abnormalities were found on DTI than would be expected by chance (P<0.001). Follow-up DTI scans in 47 subjects with traumatic brain injury 6 to 12 months after enrollment showed persistent abnormalities that were consistent with evolving injuries. CONCLUSIONS DTI findings in U.S. military personnel support the hypothesis that blast-related mild traumatic brain injury can involve axonal injury. However, the contribution of primary blast exposure as compared with that of other types of injury could not be determined directly, since none of the subjects with traumatic brain injury had isolated primary blast injury. Furthermore, many of these subjects did not have abnormalities on DTI. Thus, traumatic brain injury remains a clinical diagnosis. (Funded by the Congressionally Directed Medical Research Program and the National Institutes of Health; ClinicalTrials.gov number, NCT00785304.) PMID:21631321

Seismo-acoustic analysis of the near quarry blasts using Plostina small aperture array

NASA Astrophysics Data System (ADS)

Ghica, Daniela; Stancu, Iulian; Ionescu, Constantin

2013-04-01

Seismic and acoustic signals are important to recognize different type of industrial blasting sources in order to discriminate between them and natural earthquakes. We have analyzed the seismic events listed in the Romanian catalogue (Romplus) for the time interval between 2011 and 2012, and occurred in the Dobrogea region, in order to determine detection seismo-acoustic signals of quarry blasts by Plostina array stations. Dobrogea is known as a seismic region characterized by crustal earthquakes with low magnitudes; at the same time, over 40 quarry mines are located in the area, being sources of blasts recorded both with the seismic and infrasound sensors of the Romanian Seismic Network. Plostina seismo-acoustic array, deployed in the central part of Romania, consists of 7 seismic sites (3C broad-band instruments and accelerometers) collocated with 7 infrasound instruments. The array is particularly used for the seismic monitoring of the local and regional events, as well as for the detection of infrasonic signals produced by various sources. Considering the characteristics of the infrasound sensors (frequency range, dynamic, sensibility), the array proved its efficiency in observing the signals produced by explosions, mine explosion and quarry blasts. The quarry mines included for this study cover distances of two hundreds of kilometers from the station and routinely generate explosions that are detected as seismic and infrasonic signals with Plostina array. The combined seismo-acoustic analysis uses two types of detectors for signal identification: one, applied for the seismic signal identification, is based on array processing techniques (beamforming and frequency-wave number analysis), while the other one, which is used for infrasound detection and characterization, is the automatic detector DFX-PMCC (Progressive Multi-Channel Correlation Method). Infrasonic waves generated by quarry blasts have frequencies ranging from 0.05 Hz up to at least 6 Hz and amplitudes below 5 Pa. Seismic data analysis shows that the frequency range of the signals are above 2 Hz. Surface explosions such as quarry blasts are useful sources for checking detection and location efficiency, when seismic measurements are added. The process is crucial for discrimination purposes and for establishing of a set of ground-truth infrasound events. Ground truth information plays a key role in the interpretation of infrasound signals, by including near-field observations from industrial blasts.

Assessment and Treatment of Blast-Induced Auditory and Vestibular Injuries

DTIC Science & Technology

2016-06-01

Year 2: Q 1 – 2. Examine cochlear and vestibular tissue at 1d and 7d after bTBI Q 3 – 4. Examine cochlear and vestibular tissue at 30d and 60d...the key features of blast wave flow conditions, including the negative phase and secondary shock. However the ABS has not been previously utilized to...isoflurane can be easily adjusted by the flow control. However, due to movement artefact and nosecone constraints, it is a sub-optimal anesthetic

Development of a Comprehensive Blast-Related Auditory Injury Database (BRAID)

DTIC Science & Technology

2016-05-01

these, may result in temporary or persistent noise-induced hear- ing loss (NIHL) and tinnitus . NIHL and tinnitus present a problematic public...uals deployed to battle zones are increasingly at risk for NIHL, tinnitus , and other otologic injuries [4]. The effects of blast exposure on the...primary interest because it may be permanent and cause persistent symptoms of tinnitus [18–20] and hear- ing loss [6,17,21–23]. Blast-related middle

Fragment Size Distribution of Blasted Rock Mass

NASA Astrophysics Data System (ADS)

Jug, Jasmin; Strelec, Stjepan; Gazdek, Mario; Kavur, Boris

2017-12-01

Rock mass is a heterogeneous material, and the heterogeneity of rock causes sizes distribution of fragmented rocks in blasting. Prediction of blasted rock mass fragmentation has a significant role in the overall economics of opencast mines. Blasting as primary fragmentation can significantly decrease the cost of loading, transport, crushing and milling operations. Blast fragmentation chiefly depends on the specific blast design (geometry of blast holes drilling, the quantity and class of explosive, the blasting form, the timing and partition, etc.) and on the properties of the rock mass (including the uniaxial compressive strength, the rock mass elastic Young modulus, the rock discontinuity characteristics and the rock density). Prediction and processing of blasting results researchers can accomplish by a variety of existing software’s and models, one of them is the Kuz-Ram model, which is possibly the most widely used approach to estimating fragmentation from blasting. This paper shows the estimation of fragmentation using the "SB" program, which was created by the authors. Mentioned program includes the Kuz-Ram model. Models of fragmentation are confirmed and calibrated by comparing the estimated fragmentation with actual post-blast fragmentation from image processing techniques. In this study, the Kuz-Ram fragmentation model has been used for an open-pit limestone quarry in Dalmatia, southern Croatia. The resulting calibrated value of the rock factor enables the quality prognosis of fragmentation in further blasting works, with changed drilling geometry and blast design parameters. It also facilitates simulation in the program to optimize blasting works and get the desired fragmentations of the blasted rock mass.

Post-blasting seismicity in Rudna copper mine, Poland - source parameters analysis.

NASA Astrophysics Data System (ADS)

Caputa, Alicja; Rudziński, Łukasz; Talaga, Adam

2017-04-01

The really important hazard in Polish copper mines is high seismicity and corresponding rockbursts. Many methods are used to reduce the seismic hazard. Among others the most effective is preventing blasting in potentially hazardous mining panels. The method is expected to provoke small moderate tremors (up to M2.0) and reduce in this way a stress accumulation in the rockmass. This work presents an analysis, which deals with post-blasting events in Rudna copper mine, Poland. Using the Full Moment Tensor (MT) inversion and seismic spectra analysis, we try to find some characteristic features of post blasting seismic sources. Source parameters estimated for post-blasting events are compared with the parameters of not-provoked mining events that occurred in the vicinity of the provoked sources. Our studies show that focal mechanisms of events which occurred after blasts have similar MT decompositions, namely are characterized by a quite strong isotropic component as compared with the isotropic component of not-provoked events. Also source parameters obtained from spectral analysis show that provoked seismicity has a specific source physics. Among others, it is visible from S to P wave energy ratio, which is higher for not-provoked events. The comparison of all our results reveals a three possible groups of sources: a) occurred just after blasts, b) occurred from 5min to 24h after blasts and c) not-provoked seismicity (more than 24h after blasting). Acknowledgements: This work was supported within statutory activities No3841/E-41/S/2016 of Ministry of Science and Higher Education of Poland.

AFWL (Air Force Weapons Laboratory) HULL (Hydrodynamics Unlimited) calculations of air blast over a dam slope. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fry, M.A.; Needham, C.E.; Stucker, M.

1976-10-01

This laboratory performed Hydrodynamics Unlimited (HULL) calculations of the air blast over a dam for two yields and two pressure regions. A 5th calculation included a rigid blockhouse at the foot of the dam. Although the shielding effect of the dam reduced the incident blast wave overpressure, reflection of the shock from the valley floor raised the peak overpressure up to at least 40% of the free air value. In almost every case, the overpressure impulses near the foot of the dam were greater than or equal to free air values. The rigid blockhouse experienced the most severe overpressure environments.more » The assumption of a 50-psi hard blockhouse is reasonable. During collapse of the blockhouse, it appears to be rigid to the air flow, since it responds slowly to the rapid air blast. Although there may be other reasons to detonate the weapon on the surface of the reservoir, the best way to destroy the blockhouse and any related structures with air blast, probably would be to detonate the device downstream of the blockhouse.« less

Gangliosides and Ceramides Change in a Mouse Model of Blast Induced Traumatic Brain Injury

PubMed Central

2013-01-01

Explosive detonations generate atmospheric pressure changes that produce nonpenetrating blast induced “mild” traumatic brain injury (bTBI). The structural basis for mild bTBI has been extremely controversial. The present study applies matrix-assisted laser desorption/ionization (MALDI) mass spectrometry imaging to track the distribution of gangliosides in mouse brain tissue that were exposed to very low level of explosive detonations (2.5–5.5 psi peak overpressure). We observed major increases of the ganglioside GM2 in the hippocampus, thalamus, and hypothalamus after a single blast exposure. Moreover, these changes were accompanied by depletion of ceramides. No neurological or brain structural signs of injury could be inferred using standard light microscopic techniques. The first source of variability is generated by the Latency between blast and tissue sampling (peak intensity of the blast wave). These findings suggest that subtle molecular changes in intracellular membranes and plasmalemma compartments may be biomarkers for biological responses to mild bTBI. This is also the first report of a GM2 increase in the brains of mature mice from a nongenetic etiology. PMID:23590251

Blast Testing Issues and TBI: Experimental Models That Lead to Wrong Conclusions.

PubMed

Needham, Charles E; Ritzel, David; Rule, Gregory T; Wiri, Suthee; Young, Leanne

2015-01-01

Over the past several years, we have noticed an increase in the number of blast injury studies published in peer-reviewed biomedical journals that have utilized improperly conceived experiments. Data from these studies will lead to false conclusions and more confusion than advancement in the understanding of blast injury, particularly blast neurotrauma. Computational methods to properly characterize the blast environment have been available for decades. These methods, combined with a basic understanding of blast wave phenomena, enable researchers to extract useful information from well-documented experiments. This basic understanding must include the differences and interrelationships of static pressure, dynamic pressure, reflected pressure, and total or stagnation pressure in transient shockwave flows, how they relate to loading of objects, and how they are properly measured. However, it is critical that the research community effectively overcomes the confusion that has been compounded by a misunderstanding of the differences between the loading produced by a free field explosive blast and loading produced by a conventional shock tube. The principles of blast scaling have been well established for decades and when properly applied will do much to repair these problems. This paper provides guidance regarding proper experimental methods and offers insights into the implications of improperly designed and executed tests. Through application of computational methods, useful data can be extracted from well-documented historical tests, and future work can be conducted in a way to maximize the effectiveness and use of valuable biological test data.

Neurological Effects of Blast Injury

PubMed Central

Hicks, Ramona R.; Fertig, Stephanie J.; Desrocher, Rebecca E.; Koroshetz, Walter J.; Pancrazio, Joseph J.

2010-01-01

Over the last few years, thousands of soldiers and an even greater number of civilians have suffered traumatic injuries due to blast exposure, largely attributed to improvised explosive devices in terrorist and insurgent activities. The use of body armor is allowing soldiers to survive blasts that would otherwise be fatal due to systemic damage. Emerging evidence suggests that exposure to a blast can produce neurological consequences in the brain, but much remains unknown. To elucidate the current scientific basis for understanding blast-induced traumatic brain injury (bTBI), the NIH convened a workshop in April, 2008. A multidisciplinary group of neuroscientists, engineers, and clinicians were invited to share insights on bTBI, specifically pertaining to: physics of blast explosions, acute clinical observations and treatments, preclinical and computational models, and lessons from the international community on civilian exposures. This report provides an overview of the state of scientific knowledge of bTBI, drawing from the published literature, as well as presentations, discussions, and recommendations from the workshop. One of the major recommendations from the workshop was the need to characterize the effects of blast exposure on clinical neuropathology. Clearer understanding of the human neuropathology would enable validation of preclinical and computational models, which are attempting to simulate blast wave interactions with the central nervous system. Furthermore, the civilian experience with bTBI suggests that polytrauma models incorporating both brain and lung injuries may be more relevant to the study of civilian countermeasures than considering models with a neurological focus alone. PMID:20453776

Blasting Damage Predictions by Numerical Modeling in Siahbishe Pumped Storage Powerhouse

NASA Astrophysics Data System (ADS)

Eslami, Majid; Goshtasbi, Kamran

2018-04-01

One of the popular methods of underground and surface excavations is the use of blasting. Throughout this method of excavation, the loading resulted from blasting can be affected by different geo-mechanical and structural parameters of rock mass. Several factors affect turbulence in underground structures some of which are explosion, vibration, and stress impulses caused by the neighbouring blasting products. In investigating the blasting mechanism one should address the processes which expand with time and cause seismic events. To protect the adjoining structures against any probable deconstruction or damage, it is very important to model the blasting process prior to any actual operation. Efforts have been taken in the present study to demonstrate the potentiality of numerical methods in predicting the specified parameters in order to prevent any probable destruction. For this purpose the blasting process was modeled, according to its natural implementation, in one of the tunnels of Siahbishe dam by the 3DEC and AUTODYN 3D codes. 3DEC was used for modeling the blasting environment as well as the blast holes and AUTODYN 3D for modeling the explosion process in the blast hole. In this process the output of AUTODYN 3D, which is a result of modeling the blast hole and is in the form of stress waves, is entered into 3DEC. For analyzing the amount of destruction made by the blasting operation, the key parameter of Peak Particle Velocity was used. In the end, the numerical modeling results have been compared with the data recorded by the seismographs planted through the tunnel. As the results indicated 3DEC and AUTODYN 3D proved appropriate for analyzing such an issue. Therefore, by means of these two softwares one can analyze explosion processes prior to their implementation and make close estimation of the damage resulting from these processes.

Energies of GRB blast waves and prompt efficiencies as implied by modelling of X-ray and GeV afterglows

NASA Astrophysics Data System (ADS)

Beniamini, Paz; Nava, Lara; Duran, Rodolfo Barniol; Piran, Tsvi

2015-11-01

We consider a sample of 10 gamma-ray bursts with long-lasting ( ≳ 102 s) emission detected by Fermi/Large Area Telescope and for which X-ray data around 1 d are also available. We assume that both the X-rays and the GeV emission are produced by electrons accelerated at the external forward shock, and show that the X-ray and the GeV fluxes lead to very different estimates of the initial kinetic energy of the blast wave. The energy estimated from GeV is on average ˜50 times larger than the one estimated from X-rays. We model the data (accounting also for optical detections around 1 d, if available) to unveil the reason for this discrepancy and find that good modelling within the forward shock model is always possible and leads to two possibilities: (i) either the X-ray emitting electrons (unlike the GeV emitting electrons) are in the slow-cooling regime or (ii) the X-ray synchrotron flux is strongly suppressed by Compton cooling, whereas, due to the Klein-Nishina suppression, this effect is much smaller at GeV energies. In both cases the X-ray flux is no longer a robust proxy for the blast wave kinetic energy. On average, both cases require weak magnetic fields (10-6 ≲ ɛB ≲ 10-3) and relatively large isotropic kinetic blast wave energies 10^{53} erg<{E}_{0,kin}<10^{55} erg corresponding to large lower limits on the collimated energies, in the range 10^{52} erg<{E}_{θ ,kin}<5× 10^{52} erg for an ISM (interstellar medium) environment with n ˜ 1 cm-3 and 10^{52} erg<{E}_{θ ,kin}<10^{53} erg for a wind environment with A* ˜ 1. These energies are larger than those estimated from the X-ray flux alone, and imply smaller inferred values of the prompt efficiency mechanism, reducing the efficiency requirements on the still uncertain mechanism responsible for prompt emission.

Analysis of the X-ray emission of nine Swift afterglows

NASA Astrophysics Data System (ADS)

Panaitescu, A.; Mészáros, P.; Gehrels, N.; Burrows, D.; Nousek, J.

2006-03-01

The X-ray light curves of nine Swift XRT afterglows (050126, 050128, 050219A, 050315, 050318, 050319, 050401, 050408 and 050505) display a complex behaviour: a steep t-3.0+/-0.3 decay until ~400 s, followed by a significantly slower t-0.65+/-0.20 fall-off, which at 0.2-2 day after the burst evolves into a t-1.7+/-0.5 decay. We consider three possible models for the geometry of relativistic blast-waves (spherical outflows, non-spreading jets and spreading jets), two possible dynamical regimes for the forward shock (adiabatic and fully radiative), and we take into account a possible angular structure of the outflow and delayed energy injection in the blast-wave to identify the models which reconcile the X-ray light-curve decay with the slope of the X-ray continuum for each of the above three afterglow phases. By piecing together the various models for each phase in a way that makes physical sense, we identify possible models for the entire X-ray afterglow. The major conclusion of this work is that a long-lived episode of energy injection in the blast-wave, during which the shock energy increases at t1.0+/-0.5, is required for five afterglows and could be at work in the other four as well. For some afterglows, there may be other mechanisms that can explain the t < 400 s fast falling-off X-ray light curve (e.g. the large-angle gamma-ray burst emission), the 400 s to 5 h slow decay (e.g. a structured outflow), or the steepening at 0.2-2 day (e.g. a jet-break, a collimated outflow transiting from a wind with a r-3 radial density profile to a homogeneous or outward-increasing density region). Optical observations in conjunction with the X-ray can distinguish among these various models. Our simple tests allow the determination of the location of the cooling frequency relative to the X-ray domain and, thus, of the index of the electron power-law distribution with energy in the blast-wave. The resulting indices are clearly inconsistent with a universal value.

X-Ray Emission from Supernova Remnants.

NASA Astrophysics Data System (ADS)

Sackville Hamilton, Andrew James

1984-12-01

This thesis deals with the x-ray spectra of supernova remnants (SNRs), and in particular the x-ray spectra of the two young Type I SNRs SN1006 and Tycho. Firstly an extensive grid of nonequilibrium model spectra of SNRs in the adiabatic blast wave stage of evolution is computed, and numerous diagnostics of the state and composi- tion of the blast wave plasma are plotted over parameter space. It is demonstrated that the spectrum of an adiabatic blast wave is a good approximation to several other model SNR structures in which emission is dominated by gas undergoing quasi steady state ioni- zation near a shock front, including the one-fluid isothermal blast wave similarity solution, and the reverse shock similarity solution advocated by Chevalier for the early evolution of Type I SNe. None of these structures appears able to account for the observed spectra of SN1006 or Tycho. A new similarity solution for the early time evolution of uniform ejecta moving into an external medium is presented. It is argued that the x-ray spectra of SN1006 and Tycho are consistent with emission mainly from a reverse shock into 1.4M(,o) of initially uniform density SN ejecta consisting of pure heavy elements, moving into a uniform medium. Satisfactory fits to the observed spectra are obtained with a two layer structure of ejecta, an outer layer of unprocessed material, and an inner layer of mixed processed heavy elements. The structure of ejecta inferred is similar for both SN1006 and Tycho, the marked difference between the two spectra being attributed largely to the lower density of the ambient medium around SN1006. The results are consistent with the theory of Type I SNe as exploded white dwarfs, and resolve the apparent problems of too little iron, and too much total mass, deduced by other authors from earlier analyses of the x-ray emission of SN1006 and Tycho. Various salient aspects of the physics of a shock-heated pure heavy element plasma are discussed.

Imaging features of blast injuries: experience from 2015 Ankara bombing in Turkey

PubMed Central

Aksu, Nalan M

2016-01-01

Objective: To present the radiological features of blast-related injuries in the victims of the 10 October 2015 Ankara bombing and emphasize the importance of imaging. Methods: This retrospective descriptive study included a total of 28 patients who underwent CT scan or radiographic imaging within 6 h after the bombing on 10 October 2015. CT scans and plain radiographs were evaluated regarding mechanisms of injuries. Injuries were categorized as primary, secondary, tertiary and quaternary. The number of shrapnel and distribution of injuries were noted. Injury Severity Score (ISS) was used to rank the severity of the injury. Results: Primary blast injuries consisted of only tympanic membrane rupture. A high rate of patients (21/28 patients) in the study group suffered from secondary blast injuries. Tertiary injuries were detected in only three patients. Of the severely injured patients, five had abdominal injuries, three had thoracic injuries and six had extremity injuries. ISS was significantly higher in patients with thoracic and abdominal injuries. Conclusion: Our results after the suicide bomb attacks showed that the most common injury pattern was secondary blast injury. The torso was the most commonly injured body region, followed by the extremities. This specific injury pattern requires the use of immense radiological imaging. Hence, radiologists should be aware of the mechanisms and spectrums of blast-related injuries. Advances in knowledge: Both the unique injury pattern and the following chaos make blast-related injuries a challenge in terms of triage, diagnosis and management. Radiologists should be familiar with the wide spectrum of these unique injuries. PMID:26959613

Instability of a Planar Expansion Wave

DTIC Science & Technology

2005-10-11

Israel 3E. T. S. I. Industriales , Universidad de Castilla-La Mancha, 13071 Cuidad Real, Spain Received 18 March 2005; published 11 October 2005 An...modulation amplitude m=dx. As first shown in 3, for ideal gases with moderate values of , like 5 3 or 7 5 , m in a rippled rarefaction wave exhibits...radiating gases . The accuracy of such approximation is beyond the scope of the present paper see 17 and refer- ences therein. A blast wave

Rigid polyurethane foam as an efficient material for shock wave attenuation

NASA Astrophysics Data System (ADS)

Komissarov, P. V.; Borisov, A. A.; Sokolov, G. N.; Lavrov, V. V.

2016-09-01

A new method for reducing parameters of blast waves generated by explosions of HE charges on ground is presented. Most of the traditional techniques reduce the wave parameters at a certain distance from the charge, i.e. as a matter of fact the damping device interacts with a completely formed shock wave. The proposed approach is to use rigid polyurethane foam coating immediately the explosive charge. A distributed structure of such a foam block that provides most efficient shock wave attenuation is suggested. Results of experimental shock wave investigations recorded in tests in which HE charges have been exploded with damping devices and without it are compared.

On the propagation of decaying planar shock and blast waves through non-uniform channels

NASA Astrophysics Data System (ADS)

Peace, J. T.; Lu, F. K.

2018-05-01

The propagation of planar decaying shock and blast waves in non-uniform channels is investigated with the use of a two-equation approximation of the generalized CCW theory. The effects of flow non-uniformity for the cases of an arbitrary strength decaying shock and blast wave in the strong shock limit are considered. Unlike the original CCW theory, the two-equation approximation takes into account the effects of initial temporal flow gradients in the flow properties behind the shock as the shock encounters an area change. A generalized order-of-magnitude analysis is carried out to analyze under which conditions the classical area-Mach (A-M) relation and two-equation approximation are valid given a time constant of decay for the flow properties behind the shock. It is shown that the two-equation approximation extends the applicability of the CCW theory to problems where flow non-uniformity behind the shock is orders of magnitude above that for appropriate use of the A-M relation. The behavior of the two-equation solution is presented for converging and diverging channels and compared against the A-M relation. It is shown that the second-order approximation and A-M relation have good agreement for converging geometries, such that the influence of flow non-uniformity behind the shock is negligible compared to the effects of changing area. Alternatively, the two-equation approximation is shown to be strongly dependent on the initial magnitude of flow non-uniformity in diverging geometries. Further, in diverging geometries, the inclusion of flow non-uniformity yields shock solutions that tend toward an acoustic wave faster than that predicted by the A-M relation.

Computational Model of the Eye for Primary and Secondary Blast Trauma

DTIC Science & Technology

2015-10-01

inflicted closed eye injuries with features similar to those seen in patients with ocular blast trauma. Alphonse et al. [16] studied the effect of low...Kemper, V. Alphonse , C. McNally, I. Herring, P. Brown, J. Stitzel, and S. Duma. Response of Porcine Eyes to Blast Overpressure: Effects of Overpressure...that induces closed globe anterior and posterior pole damage. Experimental eye research, 99:63–70, 2012. [16] V. D. Alphonse , A. R. Kemper, B. T. Strom

Primary Blast Traumatic Brain Injury in the Rat: Relating Diffusion Tensor Imaging and Behavior

DTIC Science & Technology

2013-10-14

collegiate football players: the NCAA concussion study. JAMA (2003) 290:2556–63. doi:10.1001/ jama.290.19.2556 6. DePalma RG, Burris DG, Champion HR... concussions in retired pro- fessional football players. Am J Sports Med (2012) 40:2206–12. doi: 10.1177/0363546512456193 10. Verfaellie M, Lafleche G...low-blast exposures and limited excur- sions during high-blast exposures. Angular accelerations were well below the threshold for mild concussion in

Shear Forces during Blast, Not Abrupt Changes in Pressure Alone, Generate Calcium Activity in Human Brain Cells

DTIC Science & Technology

2012-06-29

the tissue-force interaction(s) and the cellular damage properties remain unresolved. Studies on a mechanical head model demonstrated high transient...that pressure transient. In vitro models of primary blast injury [5,18,19] are likewise limited by an absence of real-time, high spatial and temporal... models , as well as with human injuries in which expression of bTBI symptoms among different individuals that are exposed to the same blast is

Primary Blast Injuries in the Open and in Foxholes Resulting from Nuclear Type Detonations

DTIC Science & Technology

1991-07-01

within a few hours after blast are probably caused by suffocation from blood and fluids obstructing the airways and from intra- abdominal...ATT’N: _-COMIPAQ •.. • - i .• :_ ... . - ARMED FORCES RADIOBIOLOGY RSCH INST ATTN: DEPT OF RADIATION BIOCHEMISTRY INTERSERVICE NUCLEAR WEAPONS SCHOOL

POLLUTION EFFECTS OF ABNORMAL OPERATIONS IN IRON AND STEEL MAKING. VOLUME III. BLAST FURNACE IRONMAKING, MANUAL OF PRACTICE

EPA Science Inventory

The report is one in a six-volume series considering abnormal operating conditions (AOCs) in the primary section (sintering, blast furnace ironmaking, open hearth, electric furnace, and basic oxygen steelmaking) of an integrated iron and steel plant. Pollution standards, generall...

Development of a 3D numerical methodology for fast prediction of gun blast induced loading

NASA Astrophysics Data System (ADS)

Costa, E.; Lagasco, F.

2014-05-01

In this paper, the development of a methodology based on semi-empirical models from the literature to carry out 3D prediction of pressure loading on surfaces adjacent to a weapon system during firing is presented. This loading is consequent to the impact of the blast wave generated by the projectile exiting the muzzle bore. When exceeding a pressure threshold level, loading is potentially capable to induce unwanted damage to nearby hard structures as well as frangible panels or electronic equipment. The implemented model shows the ability to quickly predict the distribution of the blast wave parameters over three-dimensional complex geometry surfaces when the weapon design and emplacement data as well as propellant and projectile characteristics are available. Considering these capabilities, the use of the proposed methodology is envisaged as desirable in the preliminary design phase of the combat system to predict adverse effects and then enable to identify the most appropriate countermeasures. By providing a preliminary but sensitive estimate of the operative environmental loading, this numerical means represents a good alternative to more powerful, but time consuming advanced computational fluid dynamics tools, which use can, thus, be limited to the final phase of the design.

Dynamic Analysis of Tunnel in Weathered Rock Subjected to Internal Blast Loading

NASA Astrophysics Data System (ADS)

Tiwari, Rohit; Chakraborty, Tanusree; Matsagar, Vasant

2016-11-01

The present study deals with three-dimensional nonlinear finite element (FE) analyses of a tunnel in rock with reinforced concrete (RC) lining subjected to internal blast loading. The analyses have been performed using the coupled Eulerian-Lagrangian analysis tool available in FE software Abaqus/Explicit. Rock and RC lining are modeled using three-dimensional Lagrangian elements. Beam elements have been used to model reinforcement in RC lining. Three different rock types with different weathering conditions have been used to understand the response of rock when subjected to blast load. The trinitrotoluene (TNT) explosive and surrounding air have been modeled using the Eulerian elements. The Drucker-Prager plasticity model with strain rate-dependent material properties has been used to simulate the stress-strain response of rock. The concrete damaged plasticity model and Johnson-Cook plasticity model have been used for the simulation of stress-strain response of concrete and steel, respectively. The explosive (TNT) has been modeled using Jones-Wilkins-Lee (JWL) equation of state. The analysis results have been studied for stresses, deformation and damage of RC lining and the surrounding rock. It is observed that damage in RC lining results in higher stress in rock. Rocks with low modulus and high weathering conditions show higher attenuation of shock wave. Higher amount of ground shock wave propagation is observed in case of less weathered rock. Ground heave is observed under blast loading for tunnel close to ground surface.

Concepts and strategies for clinical management of blast-induced traumatic brain injury and posttraumatic stress disorder.

PubMed

Chen, Yun; Huang, Wei; Constantini, Shlomi

2013-01-01

After exposure of the human body to blast, kinetic energy of the blast shock waves might be transferred into hydraulic energy in the cardiovascular system to cause a rapid physical movement or displacement of blood (a volumetric blood surge). The volumetric blood surge moves through blood vessels from the high-pressure body cavity to the low-pressure cranial cavity, causing damage to tiny cerebral blood vessels and the blood-brain barrier (BBB). Large-scale cerebrovascular insults and BBB damage that occur globally throughout the brain may be the main causes of non-impact, blast-induced brain injuries, including the spectrum of traumatic brain injury (TBI) and posttraumatic stress disorder (PTSD). The volumetric blood surge may be a major contributor not only to blast-induced brain injuries resulting from physical trauma, but may also be the trigger to psychiatric disorders resulting from emotional and psychological trauma. Clinical imaging technologies, which are able to detect tiny cerebrovascular insults, changes in blood flow, and cerebral edema, may help diagnose both TBI and PTSD in the victims exposed to blasts. Potentially, prompt medical treatment aiming at prevention of secondary neuronal damage may slow down or even block the cascade of events that lead to progressive neuronal damage and subsequent long-term neurological and psychiatric impairment.

Simplified modeling of blast waves from metalized heterogeneous explosives

NASA Astrophysics Data System (ADS)

Zarei, Z.; Frost, D. L.

2011-09-01

The detonation of a metalized explosive generates a complex multiphase flow field. Modeling the subsequent propagation of the blast front requires a detailed knowledge of the metal particle dynamics and reaction rate. Given the uncertainties in modeling these phenomena, a much simpler, 1D compressible flow model is used to illustrate the general effects of secondary energy release due to particle reaction on the blast front properties. If the total energy release is held constant, the blast pressure and impulse are primarily dependent on the following parameters: the proportion of secondary energy released due to afterburning, the rate of energy release, the location the secondary energy release begins, and the range over which it occurs. Releasing the total energy over a longer time period in general reduces the peak blast overpressure at a given distance. However, secondary energy release reduces the rate of decay of the shock pressure, increases the local gas temperature and hence increases the velocity of the secondary shock front. As a result, for certain values of the above parameters, the peak blast impulse may be increased by a factor of about two in a region near the charge. The largest augmentation to the near-field peak impulse results when the secondary energy is released immediately behind the shock front rather than uniformly within the combustion products.

Untangling the Effect of Head Acceleration on Brain Responses to Blast Waves

PubMed Central

Mao, Haojie; Unnikrishnan, Ginu; Rakesh, Vineet; Reifman, Jaques

2015-01-01

Multiple injury-causing mechanisms, such as wave propagation, skull flexure, cavitation, and head acceleration, have been proposed to explain blast-induced traumatic brain injury (bTBI). An accurate, quantitative description of the individual contribution of each of these mechanisms may be necessary to develop preventive strategies against bTBI. However, to date, despite numerous experimental and computational studies of bTBI, this question remains elusive. In this study, using a two-dimensional (2D) rat head model, we quantified the contribution of head acceleration to the biomechanical response of brain tissues when exposed to blast waves in a shock tube. We compared brain pressure at the coup, middle, and contre-coup regions between a 2D rat head model capable of simulating all mechanisms (i.e., the all-effects model) and an acceleration-only model. From our simulations, we determined that head acceleration contributed 36–45% of the maximum brain pressure at the coup region, had a negligible effect on the pressure at the middle region, and was responsible for the low pressure at the contre-coup region. Our findings also demonstrate that the current practice of measuring rat brain pressures close to the center of the brain would record only two-thirds of the maximum pressure observed at the coup region. Therefore, to accurately capture the effects of acceleration in experiments, we recommend placing a pressure sensor near the coup region, especially when investigating the acceleration mechanism using different experimental setups. PMID:26458125

Quantifying Coastal Hazard of Airburst-Generated Tsunamis

NASA Astrophysics Data System (ADS)

Titov, V. V.; Boslough, M.

2017-12-01

The effort to prevent or mitigate the effects of an impact on Earth is known as planetary defense. A significant component of planetary defense research involves risk assessment. Much of our understanding of the risk from near-Earth objects comes from the geologic record in the form of impact craters, but not all asteroid impacts are crater-forming events. Small asteroids explode before reaching the surface, generating an airburst, and most impacts into the ocean do not penetrate the water to form a crater in the sea floor. The risk from these non-crater-forming ocean impacts and airbursts is difficult to quantify and represents a significant uncertainty in our assessment of the overall threat. One of the suggested mechanisms for the production of asteroid-generated tsunami is by direct coupling of the pressure wave to the water, analogous to the means by which a moving weather front can generate a meteotsunami. To test this hypothesis, we have run a series of airburst simulations and provided time-resolved pressure and wind profiles for tsunami modelers to use as source functions. We used hydrocodes to model airburst scenarios and provide time dependent boundary conditions as input to shallow-water wave propagation codes. The strongest and most destructive meteotsunami are generated by atmospheric pressure oscillations with amplitudes of only a few hPa, corresponding to changes in sea level of a few cm. The resulting wave is strongest when there is a resonance between the ocean and the atmospheric forcing. The blast wave from an airburst propagates at a speed close to a tsunami speed only in the deepest part of the ocean, and a Proudman resonance cannot be usually achieved even though the overpressures are orders of magnitude greater. However, blast wave profiles are N-waves in which a sharp shock wave leading to overpressure is followed by a more gradual rarefaction to a much longer-duration underpressure phase. Even though the blast outruns the water wave it is forcing, the tsunami should continue to be driven by the out-of-resonance gradient associated with the suction phase, which may depend strongly on the details of the airburst scenario. The open question is whether there are any conditions under which such an airburst can generate tsunami with substantial coastal hazard to contribute to the overall impact risk.

Numerical Simulations of Near-Field Blast Effects using Kinetic Plates

NASA Astrophysics Data System (ADS)

Neuscamman, Stephanie; Manner, Virginia; Brown, Geoffrey; Glascoe, Lee

2013-06-01

Numerical simulations using two hydrocodes were compared to near-field measurements of blast impulse associated with ideal and non-ideal explosives to gain insight into testing results and predict untested configurations. The recently developed kinetic plate test was designed to measure blast impulse in the near-field by firing spherical charges in close range from steel plates and probing plate acceleration using laser velocimetry. Plate velocities for ideal, non-ideal and aluminized explosives tests were modeled using a three dimensional hydrocode. The effects of inert additives in the explosive formulation were modeled using a 1-D hydrocode with multiphase flow capability using Lagrangian particles. The relative effect of particle impact on the plate compared to the blast wave impulse is determined and modeling is compared to free field pressure results. This work is performed under the auspices of the U.S. Department of Energy by Lawrence Livermore National Laboratory under Contract DE-AC52-07NA27344. This is abstract LLNL-ABS-622152.

Quantification of non-ideal explosion violence with a shock tube

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jackson, Scott I; Hill, Larry G

There is significant interest in quantifying the blast violence associated with various nonideal explosions. Such data is essential to evaluate the damage potential of both explosive cookoff and terrorist explosive scenarios. We present a technique designed to measure the source energy associated with a non-ideal, asymmetrical, and three-dimensional explosion. A tube is used to confine and focus energy from a blast event into a one-dimensional, quasi-planar shock front. During propagation along the length of the tube, the wave is allowed to shocksteepen into a more ideal form. Pressure transducers then measure the shock overpressure as a function of the distancemore » from the source. One-dimensional blast scaling theory allows calculation of the source energy from this data. This small-scale test method addresses cost and noise concerns as well as boosting and symmetry issues associated with large-scale, three-dimensional, blast arena tests. Results from both ideal explosives and non-ideal explosives are discussed.« less

Repeat low-level blast exposure increases transient receptor potential vanilloid 1 (TRPV1) and endothelin-1 (ET-1) expression in the trigeminal ganglion

PubMed Central

Burke, Teresa A.; Doyle Brackley, Allison; Jeske, Nathaniel A.; Cleland, Jeffery M.; Lund, Brian J.

2017-01-01

Blast-associated sensory and cognitive trauma sustained by military service members is an area of extensively studied research. Recent studies in our laboratory have revealed that low-level blast exposure increased expression of transient receptor potential vanilloid 1 (TRPV1) and endothelin-1 (ET-1), proteins well characterized for their role in mediating pain transmission, in the cornea. Determining the functional consequences of these alterations in protein expression is critical to understanding blast-related sensory trauma. Thus, the purpose of this study was to examine TRPV1 and ET-1 expression in ocular associated sensory tissues following primary and tertiary blast. A rodent model of blast injury was used in which anesthetized animals, unrestrained or restrained, received a single or repeat blast (73.8 ± 5.5 kPa) from a compressed air shock tube once or daily for five consecutive days, respectively. Behavioral and functional analyses were conducted to assess blast effects on nocifensive behavior and TRPV1 activity. Immunohistochemistry and Western Blot were also performed with trigeminal ganglia (TG) to determine TRPV1, ET-1 and glial fibrillary associated protein (GFAP) expression following blast. Increased TRPV1, ET-1 and GFAP were detected in the TG of animals exposed to repeat blast. Increased nocifensive responses were also observed in animals exposed to repeat, tertiary blast as compared to single blast and control. Moreover, decreased TRPV1 desensitization was observed in TG neurons exposed to repeat blast. Repeat, tertiary blast resulted in increased TRPV1, ET-1 and GFAP expression in the TG, enhanced nociception and decreased TRPV1 desensitization. PMID:28797041

Consortium Study of the Chelyabinsk Meteorite

NASA Technical Reports Server (NTRS)

Righter, K.; Fries, M. D.; Gibson, E. K.; Harrington, R.; Keller, L. P.; McCoy, T. J.; Morris, R. V.; Nagao, K.; Nakamura-Messenger, K.; Niles, P.;

Case Report: Lightning-Induced Pneumomediastinum.

PubMed

Blumenthal, Ryan; Saayman, Gert

2017-06-01

We present the case of a 41-year-old woman who was fatally injured during a witnessed lightning strike event and in whom autopsy revealed the unusual keraunopathological finding of overt pneumomediastinum. The possible pathophysiological mechanism(s) of causation of this phenomenon are discussed, with specific reference also to the "Macklin" effect and the role of blast overpressures associated with lightning strike. It is suggested that the latter may lead to sudden alveolar rupture, with subsequent rapid tracking of air along bronchovascular sheaths in a centripetal manner toward the hilum of the lung and thus into the mediastinum. A review of the blast literature suggests that this victim would have been exposed to a blast pressure wave of approximately 29-psi (200 kPa) to 72-psi (500 kPa) magnitude.

Elucidation of Inflammation Processes Exacerbating Neuronal Cell Damage to the Retina and Brain Visual Centers as Quest for Therapeutic Drug Targets in Rat Model of Blast Overpressure Wave Exposure

DTIC Science & Technology

2016-10-01

Righting Reflex of rats following double blast exposure. 0 4 8 12 16 20 R ig ht in g Re fle x (m in ut es ) PLACEBO FISH OIL Total Lived Died...experiments. Funding Support: Geneva Foundation contractor – WRAIR Name: Joseph B. Long, Ph.D. Project Role: Co-Investigator – WRAIR Researcher...Funding Support: Clinical Research Management contractor Name: Andrew B. Batuure Project Role: Technician - WRAIR Researcher Identifier (e.g. ORCID

Study of blast event propagation in different media using a novel ultrafast miniature optical pressure sensor

NASA Astrophysics Data System (ADS)

Zou, Xiaotian; Wu, Nan; Tian, Ye; Zhang, Hongtao; Niezrecki, Christopher; Wang, Xingwei

2011-06-01

Traumatic brain injury (TBI, also called intracranial injury) is a high potential threat to our soldiers. A helmet structural health monitoring system can be effectively used to study the effects of ballistic/blast events on the helmet and human skull to prevent soldiers from TBI. However, one of the biggest challenges lies in that the pressure sensor installed inside the helmet system must be fast enough to capture the blast wave during the transient period. In this paper, an ultrafast optical fiber sensor is presented to measure the blast signal. The sensor is based on a Fabry-Pérot (FP) interferometeric principle. An FP cavity is built between the endface of an etched optical fiber tip and the silica thin diaphragm attached on the end of a multimode optical fiber. The sensor is small enough to be installed in different locations of a helmet to measure blast pressure simultaneously. Several groups of tests regarding multi-layer blast events were conducted to evaluate the sensors' performance. The sensors were mounted in different segments of a shock tube side by side with the reference sensors, to measure a rapidly increasing pressure. The segments of the shock tube were filled with different media. The results demonstrated that our sensors' responses agreed well with those from the electrical reference sensors. In addition, the home-made shock tube could provide a good resource to study the propagation of blast event in different media.

Mitigation of explosions of hydrogen-air mixtures using bulk materials and aqueous foam

NASA Astrophysics Data System (ADS)

Medvedev, S. P.; Khomik, S. V.; Mikhalkin, V. N.; Ivantsov, A. N.; Agafonov, G. L.; Cherepanov, A. A.; Cherepanova, T. T.; Betev, A. S.

2018-01-01

The objective of this work is to determine experimentally the effectiveness of protective barriers under conditions when blast waves are generated during premixed hydrogen- air combustion in various regimes. Experiments are conducted in a vertical tube having a diameter of 54 mm and a length of up to 2 m. Blast loads are produced by acceleration of premixed hydrogen-air flames in the tube with ring obstacles. Comparative tests are performed between protection barriers made of bulk materials with different densities and aqueous foams with different expansion ratios. It is demonstrated that the degree of blast load attenuation by an aqueous foam barrier increases with decreasing molecular weight of the filling gas and increasing density (decreasing expansion ratio) of the foam. An Aerosil barrier three times thicker than a titanium-dioxide one is found to have a similar attenuating effect on blast action. However, the mass per unit area of an Aerosil barrier is lower than titanium dioxide by a factor of 6 and is comparable to foam. The observed dependence of blast load attenuation on parameters of bulk materials and aqueous foams must be taken into account in systems designed to mitigate the consequences of accidental hydrogen release and combustion.

Numerical simulations of the occupant head response in an infantry vehicle under blunt impact and blast loading conditions.

PubMed

Sevagan, Gopinath; Zhu, Feng; Jiang, Binhui; Yang, King H

2013-07-01

This article presents the results of a finite element simulation on the occupant head response in an infantry vehicle under two separated loading conditions: (1) blunt impact and (2) blast loading conditions. A Hybrid-III dummy body integrated with a previously validated human head model was used as the surrogate. The biomechanical response of the head was studied in terms of head acceleration due to the impact by a projectile on the vehicle and intracranial pressure caused by blast wave. A series of parametric studies were conducted on the numerical model to analyze the effect of some key parameters, such as seat configuration, impact velocity, and boundary conditions. The simulation results indicate that a properly designed seat and internal surface of the infantry vehicle can play a vital role in reducing the risk of head injury in the current scenarios. Comparison of the kinematic responses under the blunt impact and blast loading conditions reveals that under the current loading conditions, the acceleration pulse in the blast scenario has much higher peak values and frequency than blunt impact case, which may reflect different head response characteristics.

Experimental Investigation of Cavitation as a Possible Damage Mechanism in Blast-Induced Traumatic Brain Injury in Post-Mortem Human Subject Heads.

PubMed

Salzar, Robert S; Treichler, Derrick; Wardlaw, Andrew; Weiss, Greg; Goeller, Jacques

2017-04-15

The potential of blast-induced traumatic brain injury from the mechanism of localized cavitation of the cerebrospinal fluid (CSF) is investigated. While the mechanism and criteria for non-impact blast-induced traumatic brain injury is still unknown, this study demonstrates that local cavitation in the CSF layer of the cranial volume could contribute to these injuries. The cranial contents of three post-mortem human subject (PMHS) heads were replaced with both a normal saline solution and a ballistic gel mixture with a simulated CSF layer. Each were instrumented with multiple pressure transducers and placed inside identical shock tubes at two different research facilities. Sensor data indicates that cavitation may have occurred in the PMHS models at pressure levels below those for a 50% risk of blast lung injury. This study points to skull flexion, the result of the shock wave on the front of the skull leading to a negative pressure in the contrecoup, as a possible mechanism that contributes to the onset of cavitation. Based on observation of intracranial pressure transducer data from the PMHS model, cavitation onset is thought to occur from approximately a 140 kPa head-on incident blast.

Primary Blast Injury Criteria for Animal/Human TBI Models using Field Validated Shock Tubes

DTIC Science & Technology

2016-09-01

Software, Inc., San Jose, CA). Dose-response models for heart rate and pulmonary injury were fitted with Origin 9.0 software (OriginLab Corp...impulse. We observed only a few cases where pathological score exceeded 21 for the blast 7 strength higher than 300 kPa BOP with high standard...average heart rates (ΔHR) decreased gradually with increase in blast intensity: -29±10 (60 kPa), - 26±20 (100 kPa), -43±26 (130 kPa), -62±21 (190

Surface assessment and modification of concrete using abrasive blasting

NASA Astrophysics Data System (ADS)

Millman, Lauren R.

Composite systems are applied to concrete substrates to strengthen and extend the service life. Successful restoration or rehabilitation requires surface preparation prior to the application of the overlay. Surface coatings, waterproofing systems, and other external surface applications also require surface preparation prior to application. Abrasive blast media is often used to clean and uniformly roughen the substrate. The appropriate surface roughness is necessary to facilitate a strong bond between the existing substrate and overlay. Thus, surface modification using abrasive blast media (sand and dry ice), their respective environmental effects, surface roughness characterization prior to and after blasting, and the adhesion between the substrate and overlay are the focus of this dissertation. This dissertation is comprised of an introduction, a literature review, and four chapters, the first of which addresses the environmental effects due to abrasive blasting using sand, water, and dry ice. The assessment considered four response variables: carbon dioxide (CO2) emissions, fuel and energy consumption, and project duration. The results indicated that for sand blasting and water jetting, the primary factor contributing to environmental detriment was CO22 emissions from vehicular traffic near the construction site. The second chapter is an analysis of the International Concrete Repair Institute's (ICRI) concrete surface profiles (CSPs) using 3-D optical profilometry. The primary objective was to evaluate the suitability of approximating the 3-D surface (areal) parameters with those extracted from 2-D (linear) profiles. Four profile directions were considered: two diagonals, and lines parallel and transverse to the longitudinal direction of the mold. For any CSP mold, the estimation of the 3-D surface roughness using a 2-D linear profile resulted in underestimation and overestimation errors exceeding 50%, demonstrating the inadequacy of 2-D linear profiles to approximate the 3-D concrete surface profiles. The errors were reduced when a weighted average of the four linear profiles approximated the corresponding 3-D parameter. The following chapter considers the parametric and sensitivity of concrete surface topography measurements. The weighted average of the four 2-D profiles consistently resulted in underestimation of the corresponding 3-D parameters: the dispersion of surface elevations (Sq) and the roughness (Sa). Results indicated the 3-D parameter, Sq, had the least sensitivity to data point reduction. The final chapter investigated surface modification using dry ice and sand blasting. The overall objective was to evaluate the change in the 3-D surface roughness (Sa) following blasting as functions of mix design and as induced by freeze-thaw cycling, and to compare the results obtained using dry ice with those obtained using sand as the blasting media. In general, sand blasting produced larger changes in Sa compared to dry ice blasting for the concrete mix designs considered. The primary mechanism responsible for altering the surface topography of the concrete was the scaling of the superficial cement paste layer on the exposed surface, which was due to freeze-thaw cycling. The largest relative change in roughness following blasting occurred in the control samples, which had not undergone freeze-thaw cycling.

Revisiting the emission from relativistic blast waves in a density-jump medium

DOE Office of Scientific and Technical Information (OSTI.GOV)

Geng, J. J.; Huang, Y. F.; Dai, Z. G.

2014-09-01

Re-brightening bumps are frequently observed in gamma-ray burst afterglows. Many scenarios have been proposed to interpret the origin of these bumps, of which a blast wave encountering a density-jump in the circumburst environment has been questioned by recent works. We develop a set of differential equations to calculate the relativistic outflow encountering the density-jump by extending the work of Huang et al. This approach is a semi-analytic method and is very convenient. Our results show that late high-amplitude bumps cannot be produced under common conditions, rather only a short plateau may emerge even when the encounter occurs at an earlymore » time (<10{sup 4} s). In general, our results disfavor the density-jump origin for those observed bumps, which is consistent with the conclusion drawn from full hydrodynamics studies. The bumps thus should be caused by other scenarios.« less

Blast waves from violent explosive activity at Yasur Volcano, Vanuatu

NASA Astrophysics Data System (ADS)

Marchetti, E.; Ripepe, M.; Delle Donne, D.; Genco, R.; Finizola, A.; Garaebiti, E.

2013-11-01

and seismic waveforms were collected during violent strombolian activity at Yasur Volcano (Vanuatu). Averaging ~3000 seismic events showed stable waveforms, evidencing a low-frequency (0.1-0.3 Hz) signal preceding ~5-6 s the explosion. Infrasonic waveforms were mostly asymmetric with a sharp compressive (5-106 Pa) onset, followed by a small long-lasting rarefaction phase. Regardless of the pressure amplitude, the ratio between the positive and negative phases was constant. These waveform characteristics closely resembled blast waves. Infrared imagery showed an apparent cold spherical front ~20 m thick, which moved between 342 and 405 m/s before the explosive hot gas/fragments cloud. We interpret this cold front as that produced by the vapor condensation induced by the passage of the shock front. We suggest that violent strombolian activity at Yasur was driven by supersonic dynamics with gas expanding at 1.1 Mach number inside the conduit.

The Supercritical Pile Model: Prompt Emission Across the Electromagnetic Spectrum

NASA Technical Reports Server (NTRS)

Kazanas, Demos; Mastichiadis, A.

2008-01-01

The "Supercritical Pile" GRB model is an economical model that provides the dissipation necessary to convert explosively the energy stored in relativistic protons in the blast wave of a GRB into radiation; at the same time it produces spectra whose luminosity peaks at 1 MeV in the lab frame, the result of the kinematics of the proton-photon - pair production reaction that effects the conversion of proton energy to radiation. We outline the fundamental notions behind the "Supercritical Pile" model and discuss the resulting spectra of the prompt emission from optical to gamma-ray energies of order Gamma^2 m_ec^2, (Gamma is the Lorentz factor of the blast wave) present even in the absence of an accelerated particle distribution and compare our results to bursts that cover this entire energy range. Particular emphasis is given on the emission at the GLAST energy range both in the prompt and the afterglow stages of the burst.

High resolution seismic tomography imaging of Ireland with quarry blast data

NASA Astrophysics Data System (ADS)

Arroucau, P.; Lebedev, S.; Bean, C. J.; Grannell, J.

2017-12-01

Local earthquake tomography is a well established tool to image geological structure at depth. That technique, however, is difficult to apply in slowly deforming regions, where local earthquakes are typically rare and of small magnitude, resulting in sparse data sampling. The natural earthquake seismicity of Ireland is very low. That due to quarry and mining blasts, on the other hand, is high and homogeneously distributed. As a consequence, and thanks to the dense and nearly uniform coverage achieved in the past ten years by temporary and permanent broadband seismological stations, the quarry blasts offer an alternative approach for high resolution seismic imaging of the crust and uppermost mantle beneath Ireland. We detected about 1,500 quarry blasts in Ireland and Northern Ireland between 2011 and 2014, for which we manually picked more than 15,000 P- and 20,000 S-wave first arrival times. The anthropogenic, explosive origin of those events was unambiguously assessed based on location, occurrence time and waveform characteristics. Here, we present a preliminary 3D tomographic model obtained from the inversion of 3,800 P-wave arrival times associated with a subset of 500 events observed in 2011, using FMTOMO tomographic code. Forward modeling is performed with the Fast Marching Method (FMM) and the inverse problem is solved iteratively using a gradient-based subspace inversion scheme after careful selection of damping and smoothing regularization parameters. The results illuminate the geological structure of Ireland from deposit to crustal scale in unprecedented detail, as demonstrated by sensitivity analysis, source relocation with the 3D velocity model and comparisons with surface geology.

Analysis of MINIE2013 Explosion Air-Blast Data

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schnurr, Julie M.; Rodgers, Arthur J.; Kim, Keehoon

We report analysis of air-blast overpressure measurements from the MINIE2013 explosive experiments. The MINIE2013 experiment involved a series of nearly 70 near-surface (height-ofburst, HOB, ranging from -1 to +4 m) low-yield (W=2-20 kg TNT equivalent) chemical highexplosives tests that were recorded at local distances (230 m – 28.5 km). Many of the W and HOB combinations were repeated, allowing for quantification of the variability in air-blast features and corresponding yield estimates. We measured canonical signal features (peak overpressure, impulse per unit area, and positive pulse duration) from the air-blast data and compared these to existing air-blast models. Peak overpressure measurementsmore » showed good agreement with the models at close ranges but tended to attenuate more rapidly at longer range (~ 1 km), which is likely caused by upward refraction of acoustic waves due to a negative vertical gradient of sound speed. We estimated yields of the MINIE2013 explosions using the Integrated Yield Determination Tool (IYDT). Errors of the estimated yields were on average within 30% of the reported yields, and there were no significant differences in the accuracy of the IYDT predictions grouped by yield. IYDT estimates tend to be lower than ground truth yields, possibly because of reduced overpressure amplitudes by upward refraction. Finally, we report preliminary results on a development of a new parameterized air-blast waveform.« less

Blast biology: a study of the primary and tertiary effects of blast in open underground protective shelters. Project 33. 1 of Operation Plumbbob

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ricmond, D.R.; Taborelli, R.V.; Bowen, I.G.

1959-02-01

Dogs, pigs, rabbits, guinea pigs, and mice were exposed to nuclear detonations in two open underground partitioned shelters. The shelters were of similar construction, and each was exposed to separate detonations. Each inner chamber filled through its own orifice; thus four separate pressure environments were obtained. An aerodynamic mound was placed over the escape hatch of each structure to determine its effect on the pressure-curve shape inside the chamber. In one test a sieve plate bolted across the top of the mound was evaluated. Wind protective baffles of solid plate and of heavy wire screen were installed in the sheltersmore » to compare primary and tertiary blast effects on dogs. The shelters also contained static and dynamic pressure gages, radiation detectors, telemetering devices, and, in one test, air-temperature measuring instruments, dust-collecting trays, and eight pigs for the biological assessment of thermal effects. One dog was severely injured from tertiary blast effects associated with a maximal dynamic pressure (Q) of 10.5 psi, and one was undamaged with a maximal Q of 2 psi. Primary blast effects resulting from peak overpressures of 30.3, 25.5, 9.5, and 4.1 psi were minimal. The mortality was 19% of the mice exposed to a peak pressure of 30.3 psi and 5 and 3% of the guinea pigs and mice exposed to a peak pressure of 25.5 psi. Many of the rabbits, guinea pigs, and mice sustained slight lung hemorrhages at maximum pressues of 25.5 and 30.3 psi. Eardrum perforation data for all species, except mice, were recorded. Following shot 2, thermal effects were noted. Animals of the groups saved for observation have died from ionizing-radiation effects.« less

BLAST BIOLOGY--A STUDY OF THE PRIMARY AND TERTIARY EFFECTS OF BLAST IN OPEN UNDERGROUND PROTECTIVE SHELTERS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ricmond, D.R.; Taborelli, R.V.; Bowen, I.G.

1959-02-01

Dogs, pigs, rabbits, guinea pigs, and mice were exposed to nuclear detonatiors in two open underground pantitioned shelters. The shelters were of similar constructions and each was exposed to separate detonations. Each inner chamber filled through its own orifice; thus four separate pressure enviromments were obtained. An aerodynamic mound was placed over the escape hatch of each structure to determine its effect on the pressurecurve shape inside the chamber. In one test a sieve plate bolted across the top of the mound was evaluated. Wind protective baffles of solid plate and of heavy wire screen were installed in the sheltersmore » to compare primary and tertiary blast effects on dogs. The shelters also contained static and dynamic pressure gages, radiation detectors, telemetering devices, and, in one test, air-temperature measuring instruments, dustcollecting trays, and eight pigs for the biological assessment of thermal effects. One dog was severely injured from tertiary blast effects associated with a maximal dynamic pressure (Q) of 10.5 psi, and one was undamaged with a maximal Q of 2 psi. Primary blast effects resulting from peak overpressures of 30.3, 25.5, 9.5. and 4.1 psi were minimal. The mortality was 19 per cent of the mice exposed to a peak pressure of 30.3 psi and 5 and 3 per cent of the guinea pigs and mice exposed to a peak pressure of 25.5 psi. Many of the rabbits, guinea pigs, and mice sustained slight lung hemorrhages at maximum pressures of 25.5 and 30.3 psi. Eardrum perforation data for all species, except mice, were recorded. Following shot 2, thermal effects were noted. Animals of the groups saved for observation have died from ionizing-radiation effects. (auth)« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Uhm, Z. Lucas; Zhang Bing; Hascoeet, Romain

We perform a detailed study on the dynamics of a relativistic blast wave with the presence of a long-lived reverse shock (RS). Although a short-lived RS has been widely considered, the RS is believed to be long-lived as a consequence of a stratification expected on the ejecta Lorentz factors. The existence of a long-lived RS causes the forward shock (FS) dynamics to deviate from a self-similar Blandford-McKee solution. Employing the ''mechanical model'' that correctly incorporates the energy conservation, we present an accurate solution for both the FS and RS dynamics. We conduct a sophisticated calculation of the afterglow emission. Adoptingmore » a Lagrangian description of the blast wave, we keep track of an adiabatic evolution of numerous shells between the FS and RS. An evolution of the electron spectrum is also followed individually for every shell. We then find the FS and RS light curves by integrating over the entire FS and RS shocked regions, respectively. Exploring a total of 20 different ejecta stratifications, we explain in detail how a stratified ejecta affects its blast wave dynamics and afterglow light curves. We show that, while the FS light curves are not sensitive to the ejecta stratifications, the RS light curves exhibit much richer features, including steep declines, plateaus, bumps, re-brightenings, and a variety of temporal decay indices. These distinctive RS features may be observable if the RS has higher values of the microphysics parameters than the FS. We discuss possible applications of our results in understanding the gamma-ray burst afterglow data.« less

Hydrodynamic Simulations of Kepler's Supernova Remnant

NASA Astrophysics Data System (ADS)

Sullivan, Jessica; Blondin, John; Borkowski, Kazik; Reynolds, Stephen

2018-01-01

Kepler’s supernova remnant contains unusual features that strongly suggest an origin in a single-degenerate Type Ia explosion, including anisotropic circumstellar medium (CSM), a strong brightness gradient, and spatially varying expansion proper motions. We present 3Dhydrodynamic simulations to test a picture in which Kepler's progenitor binary emitted a strong asymmetric wind, densest in the orbital plane, while the system moved at high velocity through the ISM. We simulate the creation of the presupernova environment as well as the supernova blast wave, using the VH-1 grid-based hydrodynamics code. We first modeled an anisotropic wind to create an asymmetric bowshock around the progenitor, then the blast wave from thesupernova. The final simulation places both previous model pieces onto a single grid and allows the blast wave to expand into the bowshock. Models were completed on a Yin-Yang grids with matching angular resolutions. By manipulating parameters that control the asymmetry of the system, we attempted to find conditions that recreated the current state of Kepler. We analyzed these models by comparing images of Kepler from the Chandra X-ray Observatory to line-of-sight projections from the model results. We also present comparisons of simulated expansion velocities with recent observations of X-ray proper motions from Chandra images. We were able to produce models that contained similar features to those seen in Kepler. We find the greatest resemblance to Kepler images with a presupernova wind with an equator-to-pole density contrast of 3 and a moderately disk-like CSM at a 5° angle between equatorial plane and system motion.

PAIR-DOMINATED GeV-OPTICAL FLASH IN GRB 130427A

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vurm, Indrek; Hascoët, Romain; Beloborodov, Andrei M., E-mail: indrek.vurm@gmail.com

2014-07-10

We show that the light curve of the double GeV+optical flash in GRB 130427A is consistent with radiation from the blast wave in a wind-type medium with density parameter A = ρr {sup 2} ∼ 5 × 10{sup 10} g cm{sup –1}. The peak of the flash is emitted by copious e {sup ±} pairs created and heated in the blast wave; our first-principle calculation determines the pair-loading factor and temperature of the shocked plasma. Using detailed radiative transfer simulations, we reconstruct the observed double flash. The optical flash is dominated by synchrotron emission from the thermal plasma behind the forward shock, andmore » the GeV flash is produced via inverse Compton (IC) scattering by the same plasma. The seed photons for IC scattering are dominated by the prompt MeV radiation during the first tens of seconds, and by the optical to X-ray afterglow thereafter. IC cooling of the thermal plasma behind the forward shock reproduces all GeV data from a few seconds to ∼1 day. We find that the blast wave Lorentz factor at the peak of the flash is Γ ≈ 200, and the forward shock magnetization is ε{sub B} ∼ 2 × 10{sup –4}. An additional source is required by the data in the optical and X-ray bands at times >10{sup 2} s; we speculate that this additional source may be a long-lived reverse shock in the explosion ejecta.« less

Simulation of primary-slag melting behavior in the cohesive zone of a blast furnace, considering the effect of Al{sub 2}O{sub 3}, Fe{sub t}O, and basicity in the sinter ore

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hino, Mitsutaka; Nagasaka, Tetsuya; Katsumata, Akitoshi

1999-08-01

The alumina content in the iron ore imported to Japan is increasing year by year, and some problems in blast furnace operation, due to the use of the high-alumina-containing sinter, have already been reported. In order to clarify the mechanism of the harmful effect of alumina on the blast furnace operation, the behavior of the primary melt, which is formed in the sinter at the cohesive zone of the blast furnace, has been simulated by dripping slag through an iron or oxide funnel. The effects of basicity, Al{sub 2}O{sub 3}, and Fe{sub t}O contents in the five slag systems onmore » the dripping temperature and weight of slag remaining on the funnel have been discussed. It was found that the eutectic melt formed in the sinter would play an important role in the dripping behavior of the slag in the blast furnace through the fine porosity of the reduced iron and ore particles. Al{sub 2}O{sub 3} increased the weight of the slag remaining on the funnel, and its effect became very significant in the acidic and low-Fe{sub t}O-containing slag. It was estimated that the increase of the weight of the slag remaining on the funnel by Al{sub 2}O{sub 3} in the ore could result in a harmful effect on the permeability resistance and an indirect reduction rate of the sinter in the blast furnace.« less

Numerical simulation of blast wave propagation in vicinity of standalone prism on flat plate

NASA Astrophysics Data System (ADS)

Valger, Svetlana; Fedorova, Natalya; Fedorov, Alexander

2018-03-01

In the paper, numerical simulation of shock wave propagation in the vicinity of a standalone prism and a prism with a cavity in front of it was carried out. The modeling was based on the solution of 3D Euler equations and Fluent software was used as a main computational tool. The algorithm for local dynamic mesh adaptation to high gradients of pressure was applied. The initial stage of the explosion of condensed explosive was described with the help of "Compressed balloon method". The research allowed describing the characteristic stages of the blast in a semi-closed space, the structure of secondary shock waves and their interaction with obstacles. The numerical approach in Fluent based on combining inviscid gas dynamics methods and "Compressed balloon method" was compared with the method which had been used by the authors earlier with the help of AUTODYN and which is based on the use of the hydrodynamic model of a material to describe state of detonation products. For the problem of shock wave propagation in the vicinity of standalone prism the comparison of the simulation results obtained using both the methods with the experimental data was performed on the dependence of static pressure and effective momentum on time for the characteristic points located on prism walls.

Prevalence of Cerebral Microhemorrhage following Chronic Blast-Related Mild Traumatic Brain Injury in Military Service Members Using Susceptibility-Weighted MRI.

PubMed

Lotan, E; Morley, C; Newman, J; Qian, M; Abu-Amara, D; Marmar, C; Lui, Y W

2018-05-24

Cerebral microhemorrhages are a known marker of mild traumatic brain injury. Blast-related mild traumatic brain injury relates to a propagating pressure wave, and there is evidence that the mechanism of injury in blast-related mild traumatic brain injury may be different from that in blunt head trauma. Two recent reports in mixed cohorts of blunt and blast-related traumatic brain injury in military personnel suggest that the prevalence of cerebral microhemorrhages is lower than in civilian head injury. In this study, we aimed to characterize the prevalence of cerebral microhemorrhages in military service members specifically with chronic blast-related mild traumatic brain injury. Participants were prospectively recruited and underwent 3T MR imaging. Susceptibility-weighted images were assessed by 2 neuroradiologists independently for the presence of cerebral microhemorrhages. Our cohort included 146 veterans (132 men) who experienced remote blast-related mild traumatic brain injury (mean, 9.4 years; median, 9 years after injury). Twenty-one (14.4%) reported loss of consciousness for <30 minutes. Seventy-seven subjects (52.7%) had 1 episode of blast-related mild traumatic brain injury; 41 (28.1%) had 2 episodes; and 28 (19.2%) had >2 episodes. No cerebral microhemorrhages were identified in any subject, as opposed to the frequency of SWI-detectable cerebral microhemorrhages following blunt-related mild traumatic brain injury in the civilian population, which has been reported to be as high as 28% in the acute and subacute stages. Our results may reflect differences in pathophysiology and the mechanism of injury between blast- and blunt-related mild traumatic brain injury. Additionally, the chronicity of injury may play a role in the detection of cerebral microhemorrhages. © 2018 by American Journal of Neuroradiology.

In silico investigation of blast-induced intracranial fluid cavitation as it potentially leads to traumatic brain injury

DOE Office of Scientific and Technical Information (OSTI.GOV)

Haniff, S.; Taylor, P. A.

In this paper, we conducted computational macroscale simulations predicting blast-induced intracranial fluid cavitation possibly leading to brain injury. To further understanding of this problem, we developed microscale models investigating the effects of blast-induced cavitation bubble collapse within white matter axonal fiber bundles of the brain. We model fiber tracks of myelinated axons whose diameters are statistically representative of white matter. Nodes of Ranvier are modeled as unmyelinated sections of axon. Extracellular matrix envelops the axon fiber bundle, and gray matter is placed adjacent to the bundle. Cavitation bubbles are initially placed assuming an intracranial wave has already produced them. Pressuremore » pulses, of varied strengths, are applied to the upper boundary of the gray matter and propagate through the model, inducing bubble collapse. Simulations, conducted using the shock wave physics code CTH, predict an increase in pressure and von Mises stress in axons downstream of the bubbles after collapse. This appears to be the result of hydrodynamic jetting produced during bubble collapse. Interestingly, results predict axon cores suffer significantly lower shear stresses from proximal bubble collapse than does their myelin sheathing. Finally, simulations also predict damage to myelin sheathing, which, if true, degrades axonal electrical transmissibility and general health of the white matter structures in the brain.« less

In silico investigation of blast-induced intracranial fluid cavitation as it potentially leads to traumatic brain injury

DOE PAGES

Haniff, S.; Taylor, P. A.

2017-10-17

In this paper, we conducted computational macroscale simulations predicting blast-induced intracranial fluid cavitation possibly leading to brain injury. To further understanding of this problem, we developed microscale models investigating the effects of blast-induced cavitation bubble collapse within white matter axonal fiber bundles of the brain. We model fiber tracks of myelinated axons whose diameters are statistically representative of white matter. Nodes of Ranvier are modeled as unmyelinated sections of axon. Extracellular matrix envelops the axon fiber bundle, and gray matter is placed adjacent to the bundle. Cavitation bubbles are initially placed assuming an intracranial wave has already produced them. Pressuremore » pulses, of varied strengths, are applied to the upper boundary of the gray matter and propagate through the model, inducing bubble collapse. Simulations, conducted using the shock wave physics code CTH, predict an increase in pressure and von Mises stress in axons downstream of the bubbles after collapse. This appears to be the result of hydrodynamic jetting produced during bubble collapse. Interestingly, results predict axon cores suffer significantly lower shear stresses from proximal bubble collapse than does their myelin sheathing. Finally, simulations also predict damage to myelin sheathing, which, if true, degrades axonal electrical transmissibility and general health of the white matter structures in the brain.« less

Implementation of Smoothed Particle Hydrodynamics for Detonation of Explosive with Application to Rock Fragmentation

NASA Astrophysics Data System (ADS)

Pramanik, R.; Deb, D.

2015-07-01

The paper presents a methodology in the SPH framework to analyze physical phenomena those occur in detonation process of an explosive. It mainly investigates the dynamic failure mechanism in surrounding brittle rock media under blast-induced stress wave and expansion of high pressure product gases. A program burn model is implemented along with JWL equation of state to simulate the reaction zone in between unreacted explosive and product gas. Numerical examples of detonation of one- and two-dimensional explosive slab have been carried out to investigate the effect of reaction zone in detonation process and outward dispersion of gaseous product. The results are compared with those obtained from existing solutions. A procedure is also developed in SPH framework to apply continuity conditions between gas and rock interface boundaries. The modified Grady-Kipp damage model for the onset of tensile yielding and Drucker-Prager model for shear failure are implemented for elasto-plastic analysis of rock medium. The results show that high compressive stress causes high crack density in the vicinity of blast hole. The major principal stress (tensile) is responsible for forming radial cracks from the blast hole. Spalling zones are also developed due to stress waves reflected from the free surfaces.

In silico investigation of blast-induced intracranial fluid cavitation as it potentially leads to traumatic brain injury

NASA Astrophysics Data System (ADS)

Haniff, S.; Taylor, P. A.

2017-11-01

We conducted computational macroscale simulations predicting blast-induced intracranial fluid cavitation possibly leading to brain injury. To further understanding of this problem, we developed microscale models investigating the effects of blast-induced cavitation bubble collapse within white matter axonal fiber bundles of the brain. We model fiber tracks of myelinated axons whose diameters are statistically representative of white matter. Nodes of Ranvier are modeled as unmyelinated sections of axon. Extracellular matrix envelops the axon fiber bundle, and gray matter is placed adjacent to the bundle. Cavitation bubbles are initially placed assuming an intracranial wave has already produced them. Pressure pulses, of varied strengths, are applied to the upper boundary of the gray matter and propagate through the model, inducing bubble collapse. Simulations, conducted using the shock wave physics code CTH, predict an increase in pressure and von Mises stress in axons downstream of the bubbles after collapse. This appears to be the result of hydrodynamic jetting produced during bubble collapse. Interestingly, results predict axon cores suffer significantly lower shear stresses from proximal bubble collapse than does their myelin sheathing. Simulations also predict damage to myelin sheathing, which, if true, degrades axonal electrical transmissibility and general health of the white matter structures in the brain.

Distinguishing the Unique Neuropathological Profile of Blast Polytrauma

PubMed Central

Greenberg, Shaylen; Eck, Joseph; Lavik, Erin

2017-01-01

Traumatic brain injury sustained after blast exposure (blast-induced TBI) has recently been documented as a growing issue for military personnel. Incidence of injury to organs such as the lungs has decreased, though current epidemiology still causes a great public health burden. In addition, unprotected civilians sustain primary blast lung injury (PBLI) at alarming rates. Often, mild-to-moderate cases of PBLI are survivable with medical intervention, which creates a growing population of survivors of blast-induced polytrauma (BPT) with symptoms from blast-induced mild TBI (mTBI). Currently, there is a lack of preclinical models simulating BPT, which is crucial to identifying unique injury mechanisms of BPT and its management. To meet this need, our group characterized a rodent model of BPT and compared results to a blast-induced mTBI model. Open field (OF) performance trials were performed on rodents at 7 days after injury. Immunohistochemistry was performed to evaluate cellular outcome at day seven following BPT. Levels of reactive astrocytes (GFAP), apoptosis (cleaved caspase-3 expression), and vascular damage (SMI-71) were significantly elevated in BPT compared to blast-induced mTBI. Downstream markers of hypoxia (HIF-1α and VEGF) were higher only after BPT. This study highlights the need for unique therapeutics and prehospital management when handling BPT. PMID:28424745

Continuum modeling of neuronal cell under blast loading

PubMed Central

Jérusalem, Antoine; Dao, Ming

2012-01-01

Traumatic brain injuries have recently been put under the spotlight as one of the most important causes of accidental brain dysfunctions. Significant experimental and modeling efforts are thus ongoing to study the associated biological, mechanical and physical mechanisms. In the field of cell mechanics, progresses are also being made at the experimental and modeling levels to better characterize many of the cell functions such as differentiation, growth, migration and death, among others. The work presented here aims at bridging both efforts by proposing a continuum model of neuronal cell submitted to blast loading. In this approach, cytoplasm, nucleus and membrane (plus cortex) are differentiated in a representative cell geometry, and different material constitutive models are adequately chosen for each one. The material parameters are calibrated against published experimental work of cell nanoindentation at multiple rates. The final cell model is ultimately subjected to blast loading within a complete fluid-structure interaction computational framework. The results are compared to the nanoindentation simulation and the specific effects of the blast wave on the pressure and shear levels at the interfaces are identified. As a conclusion, the presented model successfully captures some of the intrinsic intracellular phenomena occurring during its deformation under blast loading and potentially leading to cell damage. It suggests more particularly the localization of damage at the nucleus membrane similarly to what has already been observed at the overall cell membrane. This degree of damage is additionally predicted to be worsened by a longer blast positive phase duration. As a conclusion, the proposed model ultimately provides a new three dimensional computational tool to evaluate intracellular damage during blast loading. PMID:22562014

Shock initiated reactions of reactive multi-phase blast explosives

NASA Astrophysics Data System (ADS)

Wilson, Dennis; Granier, John; Johnson, Richard; Littrell, Donald

2017-01-01

This paper describes a new class of non-ideal explosive compositions made of perfluoropolyether (PFPE), nanoaluminum, and a micron-size, high mass density, reactive metal. Unlike high explosives, these compositions release energy via a fast self-oxidized combustion wave rather than a true self-sustaining detonation. Their reaction rates are shock dependent and they can be overdriven to change their energy release rate. These compositions are fuel rich and have an extended aerobic energy release phase. The term "reactive multiphase blast" refers to the post-dispersion blast behavior: multiphase in that there are a gas phase that imparts pressure and a solid (particulate) phase that imparts energy and momentum [1]; and reactive in that the hot metal particles react with atmospheric oxygen and the explosive gas products to give an extended pressure pulse. Tantalum-based RMBX formulations were tested in two spherical core-shell configurations - an RMBX shell exploded by a high explosive core, and an RMBX core imploded by a high explosive shell. The fireball and blast characteristics were compared to a C-4 baseline charge.

Numerical study of blast characteristics from detonation of homogeneous explosives

NASA Astrophysics Data System (ADS)

Balakrishnan, Kaushik; Genin, Franklin; Nance, Doug V.; Menon, Suresh

2010-04-01

A new robust numerical methodology is used to investigate the propagation of blast waves from homogeneous explosives. The gas-phase governing equations are solved using a hybrid solver that combines a higher-order shock capturing scheme with a low-dissipation central scheme. Explosives of interest include Nitromethane, Trinitrotoluene, and High-Melting Explosive. The shock overpressure and total impulse are estimated at different radial locations and compared for the different explosives. An empirical scaling correlation is presented for the shock overpressure, incident positive phase pressure impulse, and total impulse. The role of hydrodynamic instabilities to the blast effects of explosives is also investigated in three dimensions, and significant mixing between the detonation products and air is observed. This mixing results in afterburn, which is found to augment the impulse characteristics of explosives. Furthermore, the impulse characteristics are also observed to be three-dimensional in the region of the mixing layer. This paper highlights that while some blast features can be successfully predicted from simple one-dimensional studies, the growth of hydrodynamic instabilities and the impulsive loading of homogeneous explosives require robust three-dimensional investigation.

Air pressure waves from Mount St. Helens eruptions

NASA Astrophysics Data System (ADS)

Reed, Jack W.

1987-10-01

Infrasonic recordings of the pressure wave from the Mount St. Helens (MSH) eruption on May 18, 1980, together with the weather station barograph records were used to estimate an equivalent explosion airblast yield for this eruption. Pressure wave amplitudes versus distance patterns were found to be comparable with patterns found for a small-scale nuclear explosion, the Krakatoa eruption, and the Tunguska comet impact, indicating that the MSH wave came from an explosion equivalent of about 5 megatons of TNT. The peculiar audibility pattern reported, with the blast being heard only at ranges beyond about 100 km, is explained by consideration of finite-amplitude shock propagation developments.

Single Pass Streaming BLAST on FPGAs*†

PubMed Central

Herbordt, Martin C.; Model, Josh; Sukhwani, Bharat; Gu, Yongfeng; VanCourt, Tom

2008-01-01

Approximate string matching is fundamental to bioinformatics and has been the subject of numerous FPGA acceleration studies. We address issues with respect to FPGA implementations of both BLAST- and dynamic-programming- (DP) based methods. Our primary contribution is a new algorithm for emulating the seeding and extension phases of BLAST. This operates in a single pass through a database at streaming rate, and with no preprocessing other than loading the query string. Moreover, it emulates parameters turned to maximum possible sensitivity with no slowdown. While current DP-based methods also operate at streaming rate, generating results can be cumbersome. We address this with a new structure for data extraction. We present results from several implementations showing order of magnitude acceleration over serial reference code. A simple extension assures compatibility with NCBI BLAST. PMID:19081828

Effect of casing yield stress on bomb blast impulse

NASA Astrophysics Data System (ADS)

Hutchinson, M. D.

2012-08-01

An equation to predict blast effects from cased charges was first proposed by U. Fano in 1944 and revised by E.M. Fisher in 1953 [1]. Fisher's revision provides much better matches to available blast impulse data, but still requires empirical parameter adjustments. A new derivation [2], based on the work of R.W. Gurney [3] and G.I. Taylor [4], has resulted in an equation which nearly matches experimental data. This new analytical model is also capable of being extended, through the incorporation of additional physics, such as the effects of early case fracture, finite casing thickness, casing metal strain energy dissipation, explosive gas escape through casing fractures and the comparative dynamics of blast wave and metal fragment impacts. This paper will focus on the choice of relevant case fracture strain criterion, as it will be shown that this allows the explicit inclusion of the dynamic properties of the explosive and casing metal. It will include a review and critique of the most significant earlier work on this topic, contained in a paper by Hoggatt and Recht [5]. Using this extended analytical model, good matches can readily be made to available free-field blast impulse data, without any empirical adjustments being needed. Further work will be required to apply this model to aluminised and other highly oxygen-deficient explosives.

A modern combat trauma.

PubMed

Popivanov, Georgi; Mutafchiyski, V M; Belokonski, E I; Parashkevov, A B; Koutin, G L

2014-03-01

The world remains plagued by wars and terrorist attacks, and improvised explosive devices (IED) are the main weapons of our current enemies, causing almost two-thirds of all combat injuries. We wished to analyse the pattern of blast trauma on the modern battlefield and to compare it with combat gunshot injuries. Analysis of a consecutive series of combat trauma patients presenting to two Bulgarian combat surgical teams in Afghanistan over 11 months. Demographics, injury patterns and Injury Severity Scores (ISS) were compared between blast and gunshot-injured casualties using Fisher's Exact Test. The blast victims had significantly higher median ISS (20.54 vs 9.23) and higher proportion of ISS>16 (60% vs 33.92%, p=0.008) than gunshot cases. They also had more frequent involvement of three or more body regions (47.22% vs 3.58%, p<0.0001). A significantly higher frequency of head (27.27% vs 3.57%), facial (20% vs 0%) and extremities injuries (85.45% vs 42.86%) and burns (12.72% vs 0%) was noted among the victims of explosion (p<0.0001). Based on clinical examination and diagnostic imaging, primary blast injury was identified in 24/55 (43.6%), secondary blast injury in 37 blast cases (67.3%), tertiary in 15 (27.3%) and quaternary blast injury (all burns) in seven (12.72%). Our results corroborate the 'multidimensional' injury pattern of blast trauma. The complexity of the blast trauma demands a good knowledge and a special training of the military surgeons and hospital personnel before deployment.

Hoxa9 and Hoxa10 induce CML myeloid blast crisis development through activation of Myb expression.

PubMed

Negi, Vijay; Vishwakarma, Bandana A; Chu, Su; Oakley, Kevin; Han, Yufen; Bhatia, Ravi; Du, Yang

2017-11-17

Mechanisms underlying the progression of Chronic Myeloid Leukemia (CML) from chronic phase to myeloid blast crisis are poorly understood. Our previous studies have suggested that overexpression of SETBP1 can drive this progression by conferring unlimited self-renewal capability to granulocyte macrophage progenitors (GMPs). Here we show that overexpression of Hoxa9 or Hoxa10 , both transcriptional targets of Setbp1 , is also sufficient to induce self-renewal of primary myeloid progenitors, causing their immortalization in culture. More importantly, both are able to cooperate with BCR/ABL to consistently induce transformation of mouse GMPs and development of aggressive leukemias resembling CML myeloid blast crisis, suggesting that either gene can drive CML progression by promoting the self-renewal of GMPs. We further identify Myb as a common critical target for Hoxa9 and Hoxa10 in inducing self-renewal of myeloid progenitors as Myb knockdown significantly reduced colony-forming potential of myeloid progenitors immortalized by the expression of either gene. Interestingly, Myb is also capable of immortalizing primary myeloid progenitors in culture and cooperating with BCR/ABL to induce leukemic transformation of mouse GMPs. Significantly increased levels of MYB transcript also were detected in all human CML blast crisis samples examined over chronic phase samples, further suggesting the possibility that MYB overexpression may play a prevalent role in driving human CML myeloid blast crisis development. In summary, our results identify overexpression of HOXA9 , HOXA10 , and MYB as critical drivers of CML progression, and suggest MYB as a key therapeutic target for inhibiting the self-renewal of leukemia-initiating cells in CML myeloid blast crisis patients.

Consequences of impacts of small asteroids and comets with Earth

NASA Technical Reports Server (NTRS)

Hills, J. G.

1994-01-01

The fragmentation of a small asteroid in the atmosphere greatly increases its cross sections for aerodynamic braking and energy dissipation. At a typical impact velocity of 22 km/s, the atmosphere absorbs more than half the kinetic energy of stony meteoroids with diameters, D(sub m), less than 220 m and iron meteoroids with D(sub m) less than 80 m. The corresponding diameter for comets with impact velocity 50 km/s is D(sub m) less than 1600 m. Most of the atmospheric energy dissipation occurs in a fraction of a scale height, so large meteors appear to 'explode' or 'flare' at the end of their visible paths. This dissipation of energy in the atmosphere protects the earth from direct impact damage (e.g., craters), but it produces a blast wave that can do considerable damage. The area of destruction around the impact point in which the over-pressure in the blast wave exceeds 4 lb/sq in = 2.8 x 10(exp 5) dynes/cu cm, which is enough to knock over trees and destroy buildings, increases rapidly from zero for chondritic meteoroids less than 56 m in diameter (15 megatons) to about 200 sq km for those 80 m in diameter (48 megatons); the probable diameter of the tunguska impactor of 1908 is about 80 m. Crater formation and earthquakes are not significant in land impacts by stony asteroids less than about 200 m in diameter because of the air protection. A tsunami is probably the most devastating type of damage for asteroids 200 m to 1 km in diameter. An impact by an asteroid this size anywhere in the Atlantic would devastate coastal areas on both sides of the ocean. An asteroid a few kilometers across would produce a tsunami that would reach the foothills of the Appalachian Mountains in the upper half of the East Coast of the United States. Most of Florida is protected from a tsunami by the gradual slope of the ocean off its coast, which causes most of the tsunami energy to be reflected back into the Atlantic. The atmosphere plume produced by asteroids with diameters exceeding about 120 m cannot be contained by the atmosphere, so this bubble of high-temperature gas forms a new layer on top of the atmosphere. The dust entrapped in this hot gas is likely to have optical depths exceeding tau = 10 for asteroids with diameters exceeding about 0.5 to 1 km. The optical flux from asteroids 60 m or more in diameter is enough to ignite pine forests. However, the blast wave from an impacting asteroid goes beyond the radius in which the fire starts. The blast wave tends to blow out the fire, so it is likely that the impact will char the forest, as at Tunguska, but the impact will not produce a sustained fire. Because comets dissipate their energy much higher in the atmosphere than asteroids, they illuminate a much larger region and their blast wave is weaker. So they are much more effective in producing large fires. This suggests that the KT impactor was a comet rather than an asteroid.

Minimisation of the explosion shock wave load onto the occupants inside the vehicle during trinitrotoluene charge blast.

PubMed

Krzystała, Edyta; Mężyk, Arkadiusz; Kciuk, Sławomir

2016-01-01

The aim of this study was to elaborate identification method of crew overload as a result of trinitrotoluene charge explosion under the military wheeled vehicle. During the study, an experimental military ground research was carried out. The aim of this research was to verify the mine blast resistance of the prototype wheeled vehicle according to STANG 4569 as well as the anti-explosive seat. Within the work, the original methodology was elaborated along with a prototype research statement. This article presents some results of the experimental research, thanks to which there is a possibility to estimate the crew's lives being endangered in an explosion through the measurement of acceleration as well as the pressure on the chest, head and internal organs. On the basis of our acceleration results, both effectiveness and infallibility of crew protective elements along with a blast mitigation seat were verified.

An Investigation of the Interstellar Environment of Supernova Remnant CTB87

NASA Astrophysics Data System (ADS)

Liu, Qian-Cheng; Chen, Yang; Chen, Bing-Qiu; Zhou, Ping; Wang, Xiao-Tao; Su, Yang

2018-06-01

We present a new millimeter CO-line observation toward supernova remnant (SNR) CTB 87, which was regarded purely as a pulsar wind nebula (PWN), and an optical investigation of a coincident surrounding superbubble. The CO observation shows that the SNR delineated by the radio emission is projectively covered by a molecular cloud (MC) complex at {V}LSR}=-60 to -54 {km} {{{s}}}-1. Both the symmetric axis of the radio emission and the trailing X-ray PWN appear projectively to be along a gap between two molecular gas patches at ‑58 to -57 {km} {{{s}}}-1. Asymmetric broad profiles of 12CO lines peaked at -58 {km} {{{s}}}-1 are found at the eastern and southwestern edges of the radio emission. This represents a kinematic signature consistent with an SNR–MC interaction. We also find that a superbubble, ∼37‧ in radius, appears to surround the SNR from H I 21 cm ({V}LSR}∼ -61 to -68 {km} {{{s}}}-1), WISE mid-IR, and optical extinction data. We build a multi-band photometric stellar sample of stars within the superbubble region and find 82 OB star candidates. The likely peak distance in the stars’ distribution seems consistent with the distance previously suggested for CTB 87. We suggest the arc-like radio emission is mainly a relic of the part of the blast wave that propagates into the MC complex and is now in a radiative stage while the other part of the blast wave has been expanding into the low-density region in the superbubble. This scenario naturally explains the lack of X-ray emission related to the ejecta and blast wave. The SNR–MC interaction also favors a hadronic contribution to the γ-ray emission from the CTB 87 region.

Infrared and X-Ray Evidence for Circumstellar Grain Destruction by the Blast Wave of Supernova 1987A

NASA Technical Reports Server (NTRS)

Dwek, Eliahu; Arendt, Richard G.; Bouchet, Patrice; Burrows, David N.; Challis, Peter; Danziger, John; DeBuizer James M.; Gehrz, Robert D.; Kirshner, Robert P.; McCray, Richard;

Shear wave propagation in anisotropic soft tissues and gels

PubMed Central

Namani, Ravi; Bayly, Philip V.

2013-01-01

The propagation of shear waves in soft tissue can be visualized by magnetic resonance elastography (MRE) [1] to characterize tissue mechanical properties. Dynamic deformation of brain tissue arising from shear wave propagation may underlie the pathology of blast-induced traumatic brain injury. White matter in the brain, like other biological materials, exhibits a transversely isotropic structure, due to the arrangement of parallel fibers. Appropriate mathematical models and well-characterized experimental systems are needed to understand wave propagation in these structures. In this paper we review the theory behind waves in anisotropic, soft materials, including small-amplitude waves superimposed on finite deformation of a nonlinear hyperelastic material. Some predictions of this theory are confirmed in experimental studies of a soft material with controlled anisotropy: magnetically-aligned fibrin gel. PMID:19963987

[Gangrene of the right colon after blast injury caused by abdominal gunshot wounds].

PubMed

Ignjatović, Dragan; Misović, Sidor; Jevtić, Miodrag

2005-06-01

To present a patient with an indirect secondary non-perforating blast injury of the right colon following abdominal gunshot injury, which led to necrosis and the right colon gangrene, and was surgically managed. A 26-year-old male was shot in the abdomen by four projectiles causing the secondary indirect blast injury of the right colon that turned into gangrene after 24 hours. Two days after admission, laparotomy was performed, but the primary anastomosis was not done because of the stomach and pancreatic injury, and the resection of the colon with terminal ileostomy was done instead. Three months later, the reconstruction of the colon was performed using ileocolotransverso-terminolatetral anastomosis. Secondary blast injuries should be anticipated in gunshot injuries, and could be expected to any organs, particularly the air filled ones.

A computational study of laser-supported detonation waves propagating up an oblique incident beam

NASA Astrophysics Data System (ADS)

Bohn, C. L.; Crawford, M. L.

1987-01-01

A series of numerical experiments was conducted to study the propagation of laser-supported detonation waves (LSDWs) in the case that a CO2 laser beam strikes an aluminum surface obliquely in air. A reflected shock formed at the aluminum surface was more prominent at higher angles of incidence theta of the beam, but otherwise the hydrodynamics of the plasma and the LSDW were insensitive to theta. Furthermore, the total impulse delivered to the aluminum varied approximately as 1/cos theta, a result that can be modeled with elementary blast-wave theory.

Vane Flow Direction Sensor for Blast Waves

DTIC Science & Technology

1987-02-07

APPLICATIONS INTL CORP IIT RESEARCH INSTITUTE ATTN: K SITES ATTN: DOCUMENTS LIBRARY SCIENCE APPLICATIONS INTL CORP KAMAN SCIENCES CORP ATTN: TECHNICAL...UBRARY ATTN: L MENTE ATTN: W PLOWS ATTN: LIBRARY SCIENCE APPLICATIONS INTL CORP KAMAN SCIENCE§ CORP ATTN: J MCRARY ATTN: B KINSLOW SCIENCE APPLICATIONS

Excitation and Disruption of a Giant Molecular Cloud by the Sepurnova Remnant 3C 391

NASA Technical Reports Server (NTRS)

Reach, W. T.; Rho, J.

1998-01-01

The ambient molecular gas at the distance of the remnant comprises a giant molecular cloud whose edge is closely parallel to a ridge of bright non-thermal radio continuum, which evidently delineates the blast-wave into the cloud.

Shock tubes and waves; Proceedings of the Fourteenth International Symposium on Shock Tubes and Shock Waves, University of Sydney, Sydney, Australia, August 19-22, 1983

NASA Astrophysics Data System (ADS)

Archer, R. D.; Milton, B. E.

Techniques and facilities are examined, taking into account compressor cascades research using a helium-driven shock tube, the suppression of shocks on transonic airfoils, methods of isentropically achieving superpressures, optimized performance of arc heated shock tubes, pressure losses in free piston driven shock tubes, large shock tubes designed for nuclear survivability testing, and power-series solutions of the gasdynamic equations for Mach reflection of a planar shock by a wedge. Other subjects considered are related to aerodynamics in shock tubes, shocks in dusty gases, chemical kinetics, and lasers, plasmas, and optical methods. Attention is given to vapor explosions and the blast at Mt. St. Helens, combustion reaction mechanisms from ignition delay times, the development and use of free piston wind tunnels, models for nonequilibrium flows in real shock tubes, air blast measuring techniques, finite difference computations of flow about supersonic lifting bodies, and the investigation of ionization relaxation in shock tubes.

SUPERNOVAE AND THEIR EXPANDING BLAST WAVES DURING THE EARLY EVOLUTION OF GALACTIC GLOBULAR CLUSTERS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tenorio-Tagle, Guillermo; Silich, Sergiy; Muñoz-Tuñón, Casiana

2015-11-20

Our arguments deal with the early evolution of Galactic globular clusters and show why only a few of the supernovae (SNe) products were retained within globular clusters and only in the most massive cases (M ≥ 10{sup 6} M{sub ⊙}), while less massive clusters were not contaminated at all by SNe. Here, we show that SN blast waves evolving in a steep density gradient undergo blowout and end up discharging their energy and metals into the medium surrounding the clusters. This inhibits the dispersal and the contamination of the gas left over from a first stellar generation. Only the ejecta from well-centeredmore » SNe that evolve into a high-density medium available for a second stellar generation (2SG) in the most massive clusters would be retained. These are likely to mix their products with the remaining gas, eventually leading in these cases to an Fe-contaminated 2SG.« less

Dynamic loads on human and animal surrogates at different test locations in compressed-gas-driven shock tubes

NASA Astrophysics Data System (ADS)

Alay, E.; Skotak, M.; Misistia, A.; Chandra, N.

2018-01-01

Dynamic loads on specimens in live-fire conditions as well as at different locations within and outside compressed-gas-driven shock tubes are determined by both static and total blast overpressure-time pressure pulses. The biomechanical loading on the specimen is determined by surface pressures that combine the effects of static, dynamic, and reflected pressures and specimen geometry. Surface pressure is both space and time dependent; it varies as a function of size, shape, and external contour of the specimens. In this work, we used two sets of specimens: (1) anthropometric dummy head and (2) a surrogate rodent headform instrumented with pressure sensors and subjected them to blast waves in the interior and at the exit of the shock tube. We demonstrate in this work that while inside the shock tube the biomechanical loading as determined by various pressure measures closely aligns with live-fire data and shock wave theory, significant deviations are found when tests are performed outside.

The X-Ray Evolution of the Symbiotic Star V 407 Cygni During Its 2010 Outburst

NASA Technical Reports Server (NTRS)

Mukai, K.; Nelson, T.; Chomiuk, L.; Donato, D.; Sokoloski, J.

2011-01-01

We present a summary of Swift and Suzaku X-ray observations of the 2010 nova outburst of the symbiotic star, V 407 Cyg. The Suzaku spectrum obtained on day 30 indicates the presence of the supersoft component from the white dwarf surface, as well as optically thin component from the shock between the nova ejecta and the Mira wind. The Swift observations then allow us to track the evolution of both components from day 4 to day 150. Most notable is the sudden brightening of the optically think component around day 20. We identify this as the time when the blast wave reached the immediate vicinity of the photosphere of the Mira. We have developed a simplified model of the blast wave-wind interaction that can reproduce the gross features of the X-ray evolution of V407 Cyg. If the model is correct, the binary separation is likely to be large and the mass loss rate of the Mira is likely to be relatively low.

The X-Ray Evolution of the Symbiotic Star V407 Cygni During Its 2010 Outburst

NASA Technical Reports Server (NTRS)

Mukai, K.; Nelson, T.; Chomiuk, L.; Donato, D.; Sokoloski, J.

2011-01-01

We present a summary of Swift and Suzaku X-ray observations of the 2010 nova outburst of the symbiotic star, V407 Cyg. The Suzaku spectrum obtained on day 30 indicates the presence of the supersoft component from the white dwarf surface, as well as optically thin component from the shock between the nova ejecta and the Mira wind. The Swift observations then allow us to track the evolution of both components from day 4 to day 150. Most notable is the sudden brightening of the optically think component around day 20. We identify this as the time when the blast wave reached the immediate vicinity of the photosphere of the Mira. We have developed a simplified model of the blast wave-wind interaction that can reproduce the gross features of the X-ray evolution of V407 Cyg. If the model is correct, the binary separation is likely to be large and the mass loss rate of the Mira is likely to be relatively low.

A cosmic-ray-mediated shock in the solar system

NASA Technical Reports Server (NTRS)

Eichler, D.

1981-01-01

It is pointed out that the flare-induced blast wave of Aug. 4, 1972, the most violent disturbance in the solar wind on record, produced cosmic rays with an efficiency of about 50%. Such a high efficiency is predicted by the self-regulating production model of cosmic-ray origin in shocks. Most interplanetary shocks, according to simple theoretical analysis, are not strong enough to produce cosmic rays efficiently. However, if shock strength is the key parameter governing efficiency, as present interplanetary data suggest, then shocks from supernova blasts, quasar outbursts, and other violent astrophysical phenomena should be extremely efficient sources of cosmic rays.

Basic Research Investigations into Multimode Laser and EM Launchers for Affordable Rapid Access to Space (Volumes 1 and 2)

DTIC Science & Technology

2010-08-31

not defined. Figure 5.9: Run 10-Schlieren image with only the laser-induced air-breakdown glow visible. (M=8.77, T∞=68.7 K , P∞=0.15 kPa...Run #13-Laser induced blast wave interaction with oblique shock. (M-5.95, T∞=263.7 K , P∞=5.62 kPa, Ep=196±20 J) ................ Error! Bookmark not...the air-breakdown geometry. (M-5.95, T∞=262.3 K , P∞=5.16 kPa, Ep=176±18 J)Error! Bookmark not defined. Figure 5.13: Run#16 - Laser induced blast

Compressive strength after blast of sandwich composite materials

PubMed Central

Arora, H.; Kelly, M.; Worley, A.; Del Linz, P.; Fergusson, A.; Hooper, P. A.; Dear, J. P.

2014-01-01

Composite sandwich materials have yet to be widely adopted in the construction of naval vessels despite their excellent strength-to-weight ratio and low radar return. One barrier to their wider use is our limited understanding of their performance when subjected to air blast. This paper focuses on this problem and specifically the strength remaining after damage caused during an explosion. Carbon-fibre-reinforced polymer (CFRP) composite skins on a styrene–acrylonitrile (SAN) polymer closed-cell foam core are the primary composite system evaluated. Glass-fibre-reinforced polymer (GFRP) composite skins were also included for comparison in a comparable sandwich configuration. Full-scale blast experiments were conducted, where 1.6×1.3 m sized panels were subjected to blast of a Hopkinson–Cranz scaled distance of 3.02 m kg−1/3, 100 kg TNT equivalent at a stand-off distance of 14 m. This explosive blast represents a surface blast threat, where the shockwave propagates in air towards the naval vessel. Hopkinson was the first to investigate the characteristics of this explosive air-blast pulse (Hopkinson 1948 Proc. R. Soc. Lond. A 89, 411–413 (doi:10.1098/rspa.1914.0008)). Further analysis is provided on the performance of the CFRP sandwich panel relative to the GFRP sandwich panel when subjected to blast loading through use of high-speed speckle strain mapping. After the blast events, the residual compressive load-bearing capacity is investigated experimentally, using appropriate loading conditions that an in-service vessel may have to sustain. Residual strength testing is well established for post-impact ballistic assessment, but there has been less research performed on the residual strength of sandwich composites after blast. PMID:24711494

Summary of efficiency testing of standard and high-capacity high-efficiency particulate air filters subjected to simulated tornado depressurization and explosive shock waves

DOE Office of Scientific and Technical Information (OSTI.GOV)

Smith, P.R.; Gregory, W.S.

1985-04-01

Pressure transients in nuclear facility air cleaning systems can originate from natural phenomena such as tornadoes or from accident-induced explosive blast waves. This study was concerned with the effective efficiency of high-efficiency particulate air (HEPA) filters during pressure surges resulting from simulated tornado and explosion transients. The primary objective of the study was to examine filter efficiencies at pressure levels below the point of structural failure. Both standard and high-capacity 0.61-m by 0.61-m HEPA filters were evaluated, as were several 0.2-m by 0.2-m HEPA filters. For a particular manufacturer, the material release when subjected to tornado transients is the samemore » (per unit area) for both the 0.2-m by 0.2-m and the 0.61-m by 0.61-m filters. For tornado transients, the material release was on the order of micrograms per square meter. When subjecting clean HEPA filters to simulated tornado transients with aerosol entrained in the pressure pulse, all filters tested showed a degradation of filter efficiency. For explosive transients, the material release from preloaded high-capacity filters was as much as 340 g. When preloaded high-capacity filters were subjected to shock waves approximately 50% of the structural limit level, 1 to 2 mg of particulate was released.« less

Bose--Einstein Correlations and Thermal Cluster Formation in High-energy Collisions

NASA Astrophysics Data System (ADS)

Bialas, A.; Florkowski, W.; Zalewski, K.

The blast wave model is generalized to include the production of thermal clusters, as suggested by the apparent success of the statistical model of particle production at high energies. The formulae for the HBT correlation functions and the corresponding HBT radii are derived.

A miniature pressure sensor for blast event evaluation

NASA Astrophysics Data System (ADS)

Wu, Nan; Wang, Wenhui; Tian, Ye; Niezrecki, Christopher; Wang, Xingwei

2011-06-01

Traumatic brain injury (TBI) is a great potential threat to people who deal with explosive devices. Protection from TBI has attracted more and more interest. Great efforts have been taken to the studies on the understanding of the propagation of the blast events and its effect on TBI. However, one of the biggest challenges is that the current available pressure sensors are not fast enough to capture the blast wave especially the transient period. This paper reports an ultrafast pressure sensor that could be very useful for analysis of the fast changing blast signal. The sensor is based on Fabry-Perot (FP) principle. It uses a 45º angle polished fiber sitting in a V-groove on a silicon chip. The endface of the angle polished fiber and the diaphragm which is lifted off on the side wall of the V-groove form the FP cavity. The sensor is very small and can be mounted on different locations of a helmet to measure blast pressure simultaneously. The tests were conducted at Natick Soldier Research, Development, and Engineering Center (NSRDEC) in Natick, MA. The sensors were mounted in a shock tube, side by side with the reference sensors, to measure a rapidly increased pressure. The results demonstrated that our sensors' responses agreed well with those from the electrical reference sensors and their response time is comparable.

Traumatic brain injury produced by exposure to blasts, a critical problem in current wars: biomarkers, clinical studies, and animal models

NASA Astrophysics Data System (ADS)

Dixon, C. Edward

2011-06-01

Traumatic brain injury (TBI) resulting from exposure to blast energy released by Improvised Explosive Devices (IEDs) has been recognized as the "signature injury" of Operation Iraqi Freedom and Operation Enduring Freedom. Repeated exposure to mild blasts may produce subtle deficits that are difficult to detect and quantify. Several techniques have been used to detect subtle brain dysfunction including neuropsychological assessments, computerized function testing and neuroimaging. Another approach is based on measurement of biologic substances (e.g. proteins) that are released into the body after a TBI. Recent studies measuring biomarkers in CSF and serum from patients with severe TBI have demonstrated the diagnostic, prognostic, and monitoring potential. Advancement of the field will require 1) biochemical mining for new biomarker candidates, 2) clinical validation of utility, 3) technical advances for more sensitive, portable detectors, 4) novel statistical approach to evaluate multiple biomarkers, and 5) commercialization. Animal models have been developed to simulate elements of blast-relevant TBI including gas-driven shock tubes to generate pressure waves similar to those produced by explosives. These models can reproduce hallmark clinical neuropathological responses such as neuronal degeneration and inflammation, as well as behavioral impairments. An important application of these models is to screen novel therapies and conduct proteomic, genomic, and lipodomic studies to mine for new biomarker candidates specific to blast relevant TBI.

Five Years of Mid-Infrared Evolution of the Remnant of SN 1987A: The Encounter Between the Blast Wave and the Dusty Equatorial Ring

NASA Technical Reports Server (NTRS)

Dwek, Eli; Arendt, Richard G.; Bouchet, Patrice; Burrows, David N.; Challis, Peter; Danziger, I. John; De Buizer, James M.; Gehrz, Robert D.; Park, Sangwook; Polomski, Elisha F.;

Operation Greenhouse. Scientific Director's report of atomic weapon tests at Eniwetok, 1951. Annex 1. 6, blast measurements. Part 3. Pressure near ground level. Section 4. Blast asymmetry from aerial photographs. Section 5. Ball-crusher-gauge measurements of peak pressure

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1985-04-01

Aerial motion pictures from manned aircraft were taken of the Dog, Easy, and George Shots and from a drone aircraft on Dog Shot to determine whether asymmetries in the blast waves could be detected and measured. Only one film, that taken of Dog Shot from a drone, was considered good enough to warrant detailed analysis, but this failed to yield any positive information on asymmetries. The analysis showed that failure to obtain good arrival-time data arose from a number of cases, but primarily from uncertainities in magnification and timing. Results could only be matched with reliable data from blast-velocity switchesmore » by use of large corrections. Asymnetries, if present, were judged to have been too small or to have occurred too early to be detected with the slow-frame speed used. Recommendations for better results include locating the aircraft directly overhead at the time of burst and using a camera having greater frame speed and provided with timing marks.« less

Large Blast and Thermal Simulator Reflected Wave Eliminator Study

DTIC Science & Technology

1990-03-01

it delays the passage of this wave through the test section until after the test is complete. The required length of extra duct depends on the strength...tube axis, which acts like an additional contraction effect since Se = Sj/[Cqsin(aj)]. Tii extra area is illustrated best by plotting (Se-Ae)/Ac versus...34Simulation de Choc et de Soaffie. Comimpensateur d’Ondes de Detente de Bouche pour tube a Choc de 2400 mm de diametre de Veine. Description, Compte- Renda

Abundant and equipotent founder cells establish and maintain acute lymphoblastic leukaemia.

PubMed

Elder, A; Bomken, S; Wilson, I; Blair, H J; Cockell, S; Ponthan, F; Dormon, K; Pal, D; Heidenreich, O; Vormoor, J

2017-12-01

High frequencies of blasts in primary acute lymphoblastic leukaemia (ALL) samples have the potential to induce leukaemia and to engraft mice. However, it is unclear how individual ALL cells each contribute to drive leukaemic development in a bulk transplant and the extent to which these blasts vary functionally. We used cellular barcoding as a fate mapping tool to track primograft ALL blasts in vivo. Our results show that high numbers of ALL founder cells contribute at similar frequencies to leukaemic propagation over serial transplants, without any clear evidence of clonal succession. These founder cells also exhibit equal capacity to home and engraft to different organs, although stochastic processes may alter the composition in restrictive niches. Our findings enhance the stochastic stem cell model of ALL by demonstrating equal functional abilities of singular ALL blasts and show that successful treatment strategies must eradicate the entire leukaemic cell population.

In-Vitro Approaches for Studying Blast-Induced Traumatic Brain Injury

PubMed Central

Chen, Yung Chia; Smith, Douglas H.

2009-01-01

Abstract Traumatic brain injury caused by explosive or blast events is currently divided into four phases: primary, secondary, tertiary, and quaternary blast injury. These phases of blast-induced traumatic brain injury (bTBI) are biomechanically distinct, and can be modeled in both in-vivo and in-vitro systems. The purpose of this review is to consider the mechanical phases of bTBI, how these phases are reproduced with in-vitro models, and to review findings from these models to assess how each phase of bTBI can be examined in more detail. Highlighted are some important gaps in the literature that may be addressed in the future to better identify the exact contributing mechanisms for bTBI. These in-vitro models, viewed in combination with in-vivo models and clinical studies, can be used to assess both the mechanisms and possible treatments for this type of trauma. PMID:19397424

Primary Blast Injury Criteria for Animal/Human TBI Models using Field Validated Shock Tubes

DTIC Science & Technology

2017-09-01

differential pathological response, which depends on the local tissue composition, and the response is to insult depends upon the cell type. regions...Neuroinflammation A single blast induces cell-type dependent increase in NADPH oxidase isoforms We have performed characterization of the spatial variations and...uniformly distribute and affect the whole brain. However, pathophysiological outcomes (e.g., NOX changes) in response to bTBI depend on the differential

A Review of Central Nervous System (CNS)/Cognitive Effects Due to Blast

DTIC Science & Technology

2007-02-01

head trauma: is brain damage overdiagnosed ? Part 1. J Clin Neurosci, 7(5), 400-8. Mayorga, M. A. (1997). The pathology of primary blast overpressure...Office and is available to the general public, including foreign nationals. Copies may be obtained from the Defense Technical Information Center (DTIC...http://www.dtic.mil). AFRL-RH-BR-TR-2007-0072 has been reviewed and is approved for publication in accordance with assigned distribution

An Evaluation of the Compressive Properties of Helmet Pads Pre- and Post-Shock Wave Overpressure Exposure

DTIC Science & Technology

2015-08-14

by ANSI Std. Z39.18 BLAST DROP TESTS BRAIN DAMAGE VISCOELASTICITY BRAIN CONCUSSION ...Cambridge, UK: Cambridge University Press, 1997. [5] W. C. Moss and M. J. King, "Impact response of US Army and National Football League helmet pad

An external shock origin of GRB 141028A

DOE Office of Scientific and Technical Information (OSTI.GOV)

Burgess, J. Michael; Bégué, Damien; Ryde, Felix

The prompt emission of the long, smooth, and single-pulsed gamma-ray burst, GRB 141028A, is analyzed under the guise of an external shock model. First, we fit the γ-ray spectrum with a two-component photon model, namely, synchrotron+blackbody, and then fit the recovered evolution of the synchrotron νF ν peak to an analytic model derived considering the emission of a relativistic blast wave expanding into an external medium. The prediction of the model for the νF ν peak evolution matches well with the observations. We observe the blast wave transitioning into the deceleration phase. Furthermore, we assume the expansion of the blastmore » wave to be nearly adiabatic, motivated by the low magnetic field deduced from the observations. This allows us to recover within an order of magnitude the flux density at the νF ν peak, which is remarkable considering the simplicity of the analytic model. Under this scenario we argue that the distinction between prompt and afterglow emission is superfluous as both early-time emission and late-time emission emanate from the same source. In conclusion, while the external shock model is clearly not a universal solution, this analysis opens the possibility that at least some fraction of GRBs can be explained with an external shock origin of their prompt phase.« less

An external shock origin of GRB 141028A

DOE PAGES

Burgess, J. Michael; Bégué, Damien; Ryde, Felix; ...

2016-05-05

The prompt emission of the long, smooth, and single-pulsed gamma-ray burst, GRB 141028A, is analyzed under the guise of an external shock model. First, we fit the γ-ray spectrum with a two-component photon model, namely, synchrotron+blackbody, and then fit the recovered evolution of the synchrotron νF ν peak to an analytic model derived considering the emission of a relativistic blast wave expanding into an external medium. The prediction of the model for the νF ν peak evolution matches well with the observations. We observe the blast wave transitioning into the deceleration phase. Furthermore, we assume the expansion of the blastmore » wave to be nearly adiabatic, motivated by the low magnetic field deduced from the observations. This allows us to recover within an order of magnitude the flux density at the νF ν peak, which is remarkable considering the simplicity of the analytic model. Under this scenario we argue that the distinction between prompt and afterglow emission is superfluous as both early-time emission and late-time emission emanate from the same source. In conclusion, while the external shock model is clearly not a universal solution, this analysis opens the possibility that at least some fraction of GRBs can be explained with an external shock origin of their prompt phase.« less

External front instabilities induced by a shocked particle ring.

PubMed

Rodriguez, V; Saurel, R; Jourdan, G; Houas, L

2014-10-01

The dispersion of a cylindrical particle ring by a blast or shock wave induces the formation of coherent structures which take the form of particle jets. A blast wave, issuing from the discharge of a planar shock wave at the exit of a conventional shock tube, is generated in the center of a granular medium ring initially confined inside a Hele-Shaw cell. With the present experimental setup, under impulsive acceleration, a solid particle-jet formation is observed in a quasi-two-dimensional configuration. The aim of the present investigation is to observe in detail the formation of very thin perturbations created around the external surface of the dispersed particle layer. By means of fast flow visualization with an appropriate recording window, we focus solely on the first instants during which the external particle ring becomes unstable. We find that the critical area of the destabilization of the external ring surface is constant regardless of the acceleration of the initial layer. Moreover, we observe in detail the external front perturbation wavelength, rendered dimensionless by the initial ring perimeter, and follow its evolution with the initial particle layer acceleration. We report this quantity to be constant regardless of the evolution of the initial particle layer acceleration. Finally, we can reasonably assert that external front perturbations depend solely on the material of the particles.

Uniform high order spectral methods for one and two dimensional Euler equations

NASA Technical Reports Server (NTRS)

Cai, Wei; Shu, Chi-Wang

1991-01-01

Uniform high order spectral methods to solve multi-dimensional Euler equations for gas dynamics are discussed. Uniform high order spectral approximations with spectral accuracy in smooth regions of solutions are constructed by introducing the idea of the Essentially Non-Oscillatory (ENO) polynomial interpolations into the spectral methods. The authors present numerical results for the inviscid Burgers' equation, and for the one dimensional Euler equations including the interactions between a shock wave and density disturbance, Sod's and Lax's shock tube problems, and the blast wave problem. The interaction between a Mach 3 two dimensional shock wave and a rotating vortex is simulated.

Exosomes Secreted by Apoptosis-Resistant Acute Myeloid Leukemia (AML) Blasts Harbor Regulatory Network Proteins Potentially Involved in Antagonism of Apoptosis*

PubMed Central

Wojtuszkiewicz, Anna; Schuurhuis, Gerrit J.; Kessler, Floortje L.; Piersma, Sander R.; Knol, Jaco C.; Pham, Thang V.; Jansen, Gerrit; Musters, René J. P.; van Meerloo, Johan; Assaraf, Yehuda G.; Kaspers, Gertjan J. L.; Zweegman, Sonja; Cloos, Jacqueline; Jimenez, Connie R.

2016-01-01

Expression of apoptosis-regulating proteins (B-cell CLL/lymphoma 2 - BCL-2, Myeloid Cell Leukemia 1 - MCL-1, BCL-2 like 1 - BCL-X and BCL-2-associated X protein - BAX) in acute myeloid leukemia (AML) blasts at diagnosis is associated with disease-free survival. We previously found that the initially high apoptosis-resistance of AML cells decreased after therapy, while regaining high levels at relapse. Herein, we further explored this aspect of dynamic apoptosis regulation in AML. First, we showed that the intraindividual ex vivo apoptosis-related profiles of normal lymphocytes and AML blasts within the bone marrow of AML patients were highly correlated. The expression values of apoptosis-regulating proteins were far beyond healthy control lymphocytes, which implicates the influence of microenvironmental factors. Second, we demonstrated that apoptosis-resistant primary AML blasts, as opposed to apoptosis-sensitive cells, were able to up-regulate BCL-2 expression in sensitive AML blasts in contact cultures (p = 0.0067 and p = 1.0, respectively). Using secretome proteomics, we identified novel proteins possibly engaged in apoptosis regulation. Intriguingly, this analysis revealed that major functional protein clusters engaged in global gene regulation, including mRNA splicing, protein translation, and chromatin remodeling, were more abundant (p = 4.01E-06) in secretomes of apoptosis-resistant AML. These findings were confirmed by subsequent extracellular vesicle proteomics. Finally, confocal-microscopy-based colocalization studies show that splicing factors-containing vesicles secreted by high AAI cells are taken up by low AAI cells. The current results constitute the first comprehensive analysis of proteins released by apoptosis-resistant and sensitive primary AML cells. Together, the data point to vesicle-mediated release of global gene regulatory protein clusters as a plausible novel mechanism of induction of apoptosis resistance. Deciphering the modes of communication between apoptosis-resistant blasts may in perspective lead to the discovery of prognostic tools and development of novel therapeutic interventions, aimed at limiting or overcoming therapy resistance. PMID:26801919

A Review of Research on Impulsive Loading of Marine Composites

NASA Astrophysics Data System (ADS)

Porfiri, Maurizio; Gupta, Nikhil

Impulsive loading conditions, such as those produced by blast waves, are being increasingly recognized as relevant in marine applications. Significant research efforts are directed towards understanding the impulsive loading response of traditional naval materials, such as aluminum and steel, and advanced composites, such as laminates and sandwich structures. Several analytical studies are directed towards establishing predictive models for structural response and failure of marine structures under blast loading. In addition, experimental research efforts are focused on characterizing structural response to blast loading. The aim of this review is to provide a general overview of the state of the art on analytical and experimental studies in this field that can serve as a guideline for future research directions. Reported studies cover the Office of Naval Research-Solid Mechanics Program sponsored research along with other worldwide research efforts of relevance to marine applications. These studies have contributed to developing a fundamental knowledge of the mechanics of advanced materials subjected to impulsive loading, which is of interest to all Department of Defense branches.

The High-Strain Rate Loading of Structural Biological Materials

NASA Astrophysics Data System (ADS)

Proud, W. G.; Nguyen, T.-T. N.; Bo, C.; Butler, B. J.; Boddy, R. L.; Williams, A.; Masouros, S.; Brown, K. A.

2015-10-01

The human body can be subjected to violent acceleration as a result of explosion caused by military ordinance or accident. Blast waves cause injury and blunt trauma can be produced by violent impact of objects against the human body. The long-term clinical manifestations of blast injury can be significantly different in nature and extent to those suffering less aggressive insult. Similarly, the damage seen in lower limbs from those injured in explosion incidents is in general more severe than those falling from height. These phenomena increase the need for knowledge of the short- and long-term effect of transient mechanical loading to the biological structures of the human body. This paper gives an overview of some of the results of collaborative investigation into blast injury. The requirement for time-resolved data, appropriate mechanical modeling, materials characterization and biological effects is presented. The use of a range of loading platforms, universal testing machines, drop weights, Hopkinson bars, and bespoke traumatic injury simulators are given.

40 CFR 63.1541 - Applicability.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Hazardous Air Pollutants for Primary Lead Smelting § 63.1541 Applicability. (a) The provisions of this subpart apply to the following affected sources at primary lead smelters: sinter machine, blast furnace... not apply to secondary lead smelters, lead refiners, or lead remelters. (b) Table 1 of this subpart...

Combined Effects of Primary and Tertiary Blast on Rat Brain: Characterization of a Model of Blast-induced Mild Traumatic Brain Injury

DTIC Science & Technology

2015-03-01

known as concussions ) affect ~1.3 million individuals in the US annually mostly during contact sports such as boxing, hockey, and football [1, 2]. In...disorder which has been observed in several athletes with a history of multiple concussions . In particular, phosphorylated Tau (pTau) protein...Accreditation of Laboratory Animal Care International. References [1] Laker SR. Epidemiology of concussion and mild traumatic brain injury. PM R

Olefin unit primary fractionator on-line Petro-Blast Lancing

DOE Office of Scientific and Technical Information (OSTI.GOV)

Adams, W.D.; Rutan, C.R.

1994-12-31

Today`s commodity chemicals market forces companies to find innovative ways to extend unit on line operation between turnarounds such that they will remain economically competitive. At the OxyChem Chocolate Bayou facility the Primary Fractionator, quench oil column, fouling defined the length of the run between Olefin Unit turnarounds. Polymer growth on the valve trays restricted vapor flow through the column. This increased the column pressure drop which resulted in severe flooding. The inability to cool the furnace effluent while separating the fuel oil and gasoline components would cause premature shutdowns. Fouling locations were defined using gamma scan techniques and pressuremore » surveys. Nozzles were welded and hot tapped at strategic locations around the column. A high pressure Petro-Blast Lancing technique, inserted through the nozzles, was then used to clean the trays. The operation has extended the unit run length although the column may require additional Petro-Blast Lancing before the next scheduled plant turnaround. If this schedule holds, a two year extension in the unit run length will be realized.« less

RESEARCH PAPERS : Ionospheric signature of surface mine blasts from Global Positioning System measurements

NASA Astrophysics Data System (ADS)

Calais, Eric; Bernard Minster, J.; Hofton, Michelle; Hedlin, Michael

1998-01-01

Sources such as atmospheric or buried explosions and shallow earthquakes are known to produce infrasonic pressure waves in the atmosphere Because of the coupling between neutral particles and electrons at ionospheric altitudes, these acoustic and gravity waves induce variations of the ionospheric electron density. The Global Positioning System (GPS) provides a way of directly measuring the total electron content in the ionosphere and, therefore, of detecting such perturbations in the upper atmosphere. In July and August 1996, three large surface mine blasts (1.5 Kt each) were detonated at the Black Thunder coal mine in eastern Wyoming. As part of a seismic and acoustic monitoring experiment, we deployed five dual-frequency GPS receivers at distances ranging from 50 to 200 km from the mine and were able to detect the ionospheric perturbation caused by the blasts. The perturbation starts 10 to 15 min after the blast, lasts for about 30 min, and propagates with an apparent horizontal velocity of 1200 m s- 1. Its amplitude reaches 3 × 1014 el m- 2 in the 7-3 min period band, a value close to the ionospheric perturbation caused by the M=6.7 Northridge earthquake (Calais & Minster 1995). The small signal-to-noise ratio of the perturbation can be improved by slant-stacking the electron content time-series recorded by the different GPS receivers taking into account the horizontal propagation of the perturbation. The energy of the perturbation is concentrated in the 200 to 300 s period band, a result consistent with previous observations and numerical model predictions. The 300 s band probably corresponds to gravity modes and shorter periods to acoustic modes, respectively. Using a 1-D stratified velocity model of the atmosphere we show that linear acoustic ray tracing fits arrival times at all GPS receivers. We interpret the perturbation as a direct acoustic wave caused by the explosion itself. This study shows that even relatively small subsurface events can produce ionospheric perturbations that are above the detection threshold of the GPS technique. By sensing derivative signals, which can be detected over a relatively broad region, it appears that GPS might be particularly useful for source characterization within the first acoustic quiet zone where infrasound would probably be ineffective. This suggests that dual-frequency GPS monitoring could contribute to Comprehensive Nuclear Test Ban Treaty verification.

Ionospheric Signature of Surface Mine Blasts from Global Positioning System Measurements

NASA Technical Reports Server (NTRS)

Calais, Eric; Minster, J. Bernard; Hofton, Michelle A.; Hedlin, Michael A. H.

1998-01-01

Sources such as atmospheric or buried explosions and shallow earthquakes are known to produce infrasonic pressure waves in the atmosphere. Because of the coupling between neutral particles and electrons at ionospheric altitudes, these acoustic and gravity waves induce variations of the ionospheric electron density. The Global Positioning System (GPS) provides a way of directly measuring the total electron content in the ionosphere and, therefore, of detecting such perturbations in the upper atmosphere. In July and August 1996, three large surface mine blasts (1.5 Kt each) were detonated at the Black Thunder coal mine in eastern Wyoming. As part of a seismic and acoustic monitoring- experiment, we deployed five dual-frequency GPS receivers at distances ranging from 50 to 200 km from the mine and were able to detect the ionospheric perturbation caused by the blasts. The perturbation starts 10 to 15 min after the blast, lasts for about 30 min, and propagates with an apparent horizontal velocity of 1200 meters per second. Its amplitude reaches 3 x 10 (exp 14) el per square meters in the 7-3 min period band, a value close to the ionospheric perturbation caused by the M = 6.7 Northridge earthquake. The small signal-to-noise ratio of the perturbation can be improved by slant-stacking the electron content time-series recorded by the different GPS receivers taking into account the horizontal propagation of the perturbation. The energy of the perturbation is concentrated in the 200 to 300 second period band, a result consistent with previous observations and numerical model predictions. The 300 second band probably corresponds to gravity modes and shorter periods to acoustic modes, respectively. Using a 1-D stratified velocity model of the atmosphere we show that linear acoustic ray tracing fits arrival times at all GPS receivers. We interpret the perturbation as a direct acoustic wave caused by the explosion itself. This study shows that even relatively small subsurface events can produce ionospheric perturbations that are above the detection threshold of the GPS technique. By sensing derivative signals, which can be detected over a relatively broad region, it appears that GPS might be particularly useful for source characterization within the first acoustic quiet zone where infrasound would probably be ineffective. This suggests that dual-frequency GPS monitoring could contribute to Comprehensive Nuclear Test Ban Treaty verification.

Chronic Hypopituitarism Associated with Increased Postconcussive Symptoms Is Prevalent after Blast-Induced Mild Traumatic Brain Injury

PubMed Central

Undurti, Arundhati; Colasurdo, Elizabeth A.; Sikkema, Carl L.; Schultz, Jaclyn S.; Peskind, Elaine R.; Pagulayan, Kathleen F.; Wilkinson, Charles W.

2018-01-01

The most frequent injury sustained by US service members deployed to Iraq or Afghanistan is mild traumatic brain injuries (mTBI), or concussion, by far most often caused by blast waves from improvised explosive devices or other explosive ordnance. TBI from all causes gives rise to chronic neuroendocrine disorders with an estimated prevalence of 25–50%. The current study expands upon our earlier finding that chronic pituitary gland dysfunction occurs with a similarly high frequency after blast-related concussions. We measured circulating hormone levels and accessed demographic and testing data from two groups of male veterans with hazardous duty experience in Iraq or Afghanistan. Veterans in the mTBI group had experienced one or more blast-related concussion. Members of the deployment control (DC) group encountered similar deployment conditions but had no history of blast-related mTBI. 12 of 39 (31%) of the mTBI participants and 3 of 20 (15%) veterans in the DC group screened positive for one or more neuroendocrine disorders. Positive screens for growth hormone deficiency occurred most often. Analysis of responses on self-report questionnaires revealed main effects of both mTBI and hypopituitarism on postconcussive and posttraumatic stress disorder (PTSD) symptoms. Symptoms associated with pituitary dysfunction overlap considerably with those of PTSD. They include cognitive deficiencies, mood and anxiety disorders, sleep problems, diminished quality of life, deleterious changes in metabolism and body composition, and increased cardiovascular mortality. When such symptoms are due to hypopituitarism, they may be alleviated by hormone replacement. These findings suggest consideration of routine post-deployment neuroendocrine screening of service members and veterans who have experienced blast-related mTBI and are reporting postconcussive symptoms. PMID:29515515

A study on the dynamic behavior of the Meuse/Haute-Marne argillite

NASA Astrophysics Data System (ADS)

Cai, M.; Kaiser, P. K.; Suorineni, F.; Su, K.

Excavation of underground tunnels can be conducted by tunnel boring machines (TBM) or drill-and-blast. TBMs cause minimum damage to excavation walls. Blasting effects on excavation walls depend on the care with which the blasting is executed. For blast-induced damage in excavation walls, two issues have to be addressed: rate of loss of confinement (rate of excavation) and dynamic loading from wave propagation that causes both intended and unintended damage. To address these two aspects, laboratory dynamic tests were conducted for the determination of the dynamic properties of the Meuse/Haute-Marne argillite. In the present study, 17 tensile (Brazilian) and 15 compression split Hopkinson pressure bar (SHPB) tests were conducted. The test revealed that the dynamic strengths of the argillite are strain rate dependent. The average dynamic increase factors (ratio of dynamic strength to static strength) for tensile and compressive strength are about 3.3 and 2.4, respectively. A high-speed video camera was used to visualize the initiation of failure and subsequent deformation of the specimens. The direct compression specimens were found to deform and fail uniformly around the circumference of the specimen, by a spalling process. The SHPB Brazilian tests indicated that failure occurred in tension along the line of load application. Radial fractures were also observed. The test results can be used for the development of a dynamic constitutive model for the argillite for the prediction of damage in underground excavation utilizing the drill-and blast method.

Using SPL (Spent Pot-Lining) as an Alternative Fuel in Metallurgical Furnaces

NASA Astrophysics Data System (ADS)

Gao, Lei; Mostaghel, Sina; Ray, Shamik; Chattopadyay, Kinnor

2016-09-01

Replacing coke (coal) in a metallurgical furnace with other alternative fuels is beneficial for process economics and environmental friendliness. Coal injection is a common practice in blast furnace ironmaking, and spent pot-lining (SPL) was conceptualized as an alternative to coal. SPL is a resourceful waste from primary Aluminum production, with high carbon value. Equilibrium thermodynamics was used to calculate the energy content of SPL, and the compositional changes during SPL combustion. In order to capture the kinetics and mass transfer aspects, a blast furnace tuyere region CFD model was developed. The results of SPL combustion were compared with standard PCI coals, which are commonly used in blast furnaces. The CFD model was validated with experimental results for standard high volatile coals.

Blast Exposure Causes Early and Persistent Aberrant Phospho- and Cleaved-Tau Expression in a Murine Model of Mild Blast-Induced Traumatic Brain Injury

PubMed Central

Huber, Bertrand R.; Meabon, James S.; Martin, Tobin J.; Mourad, Pierre D.; Bennett, Raymond; Kraemer, Brian C.; Cernak, Ibolja; Petrie, Eric C.; Emery, Michael J.; Swenson, Erik R.; Mayer, Cynthia; Mehic, Edin; Peskind, Elaine R.; Cook, David G.

2014-01-01

Mild traumatic brain injury (mTBI) is considered the ‘signature injury’ of combat veterans that have served during the wars in Iraq and Afghanistan. This prevalence of mTBI is due in part to the common exposure to high explosive blasts in combat zones. In addition to the threats of blunt impact trauma caused by flying objects and the head itself being propelled against objects, the primary blast overpressure (BOP) generated by high explosives is capable of injuring the brain. Compared to other means of causing TBI, the pathophysiology of mild-to-moderate BOP is less well understood. To study the consequences of BOP exposure in mice, we employed a well-established approach using a compressed gas-driven shock tube that recapitulates battlefield-relevant open-field BOP. We found that 24 hours post-blast a single mild BOP provoked elevation of multiple phosphor- and cleaved-tau species in neurons, as well as elevating manganese superoxide-dismutase (MnSOD or SOD2) levels, a cellular response to oxidative stress. In hippocampus, aberrant tau species persisted for at least 30 days post-exposure, while SOD2 levels returned to sham control levels. These findings suggest that elevated phospho- and cleaved-tau species may be among the initiating pathologic processes induced by mild blast exposure. These findings may have important implications for efforts to prevent blast-induced insults to the brain from progressing into long-term neurodegenerative disease processes. PMID:23948882

Rarefaction Wave Eliminator Concepts For A Large Blast/Thermal Simulator.

DTIC Science & Technology

1985-02-01

hard copies of the pressure-time records. Final data process- ing was completed with the computer, printer , and plotter. Plots of pressure- time records...F ATTN: Prof 0. Zinke Fayetteville, AR 72701 Cdr, CRDC, AMCCOM ATTI: 4O-SPS-IL University of California PM=-J Lawrence Livermore Lab SOM-RSP-A ATTN

78 FR 52998 - Waiver to Space Exploration Technologies Corporation of Acceptable Risk Limit for Launch

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-27

... risk. The presence of inversion layers at VAFB is common, and results in the reflection of shock waves... caused without the reflection from the inversion layer. Chances of advantageous weather conditions during... experiences unique weather conditions that exacerbate far field blast overpressure from a launch. An inversion...

Numerical simulation of long-duration blast wave evolution in confined facilities

NASA Astrophysics Data System (ADS)

Togashi, F.; Baum, J. D.; Mestreau, E.; Löhner, R.; Sunshine, D.

2010-10-01

The objective of this research effort was to investigate the quasi-steady flow field produced by explosives in confined facilities. In this effort we modeled tests in which a high explosive (HE) cylindrical charge was hung in the center of a room and detonated. The HEs used for the tests were C-4 and AFX 757. While C-4 is just slightly under-oxidized and is typically modeled as an ideal explosive, AFX 757 includes a significant percentage of aluminum particles, so long-time afterburning and energy release must be considered. The Lawrence Livermore National Laboratory (LLNL)-produced thermo-chemical equilibrium algorithm, “Cheetah”, was used to estimate the remaining burnable detonation products. From these remaining species, the afterburning energy was computed and added to the flow field. Computations of the detonation and afterburn of two HEs in the confined multi-room facility were performed. The results demonstrate excellent agreement with available experimental data in terms of blast wave time of arrival, peak shock amplitude, reverberation, and total impulse (and hence, total energy release, via either the detonation or afterburn processes.

Discovery of a z = 0.65 post-starburst BAL quasar in the DES supernova fields

DOE PAGES

Mudd, Dale; Martini, Paul; Tie, Suk Sien; ...

2017-03-23

In this paper, we present the discovery of a z = 0.65 low-ionization broad absorption line (LoBAL) quasar in a post-starburst galaxy in data from the Dark Energy Survey (DES) and spectroscopy from the Australian Dark Energy Survey (OzDES). LoBAL quasars are a minority of all BALs, and rarer still is that this object also exhibits broad Fe ii (an FeLoBAL) and Balmer absorption. This is the first BAL quasar that has signatures of recently truncated star formation, which we estimate ended about 40 Myr ago. The characteristic signatures of an FeLoBAL require high column densities, which could be explainedmore » by the emergence of a young quasar from an early, dust-enshrouded phase, or by clouds compressed by a blast wave. Finally, the age of the starburst component is comparable to estimates of the lifetime of quasars, so if we assume the quasar activity is related to the truncation of the star formation, this object is better explained by the blast wave scenario.« less

An Empirical Non-TNT Approach to Launch Vehicle Explosion Modeling

NASA Technical Reports Server (NTRS)

Blackwood, James M.; Skinner, Troy; Richardson, Erin H.; Bangham, Michal E.

2015-01-01

In an effort to increase crew survivability from catastrophic explosions of Launch Vehicles (LV), a study was conducted to determine the best method for predicting LV explosion environments in the near field. After reviewing such methods as TNT equivalence, Vapor Cloud Explosion (VCE) theory, and Computational Fluid Dynamics (CFD), it was determined that the best approach for this study was to assemble all available empirical data from full scale launch vehicle explosion tests and accidents. Approximately 25 accidents or full-scale tests were found that had some amount of measured blast wave, thermal, or fragment explosion environment characteristics. Blast wave overpressure was found to be much lower in the near field than predicted by most TNT equivalence methods. Additionally, fragments tended to be larger, fewer, and slower than expected if the driving force was from a high explosive type event. In light of these discoveries, a simple model for cryogenic rocket explosions is presented. Predictions from this model encompass all known applicable full scale launch vehicle explosion data. Finally, a brief description of on-going analysis and testing to further refine the launch vehicle explosion environment is discussed.

Discovery of a z = 0.65 post-starburst BAL quasar in the DES supernova fields

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mudd, Dale; Martini, Paul; Tie, Suk Sien

We present the discovery of a z=0.65 low-ionization broad absorption line (LoBAL) quasar in a post-starburst galaxy in data from the Dark Energy Survey (DES) and spectroscopy from the Australian Dark Energy Survey (OzDES). LoBAL quasars are a minority of all BALs, and rarer still is that this object also exhibits broad FeII (an FeLoBAL) and Balmer absorption. This is the first BAL quasar that has signatures of recently truncated star formation, which we estimate ended about 40 Myr ago. The characteristic signatures of an FeLoBAL require high column densities, which could be explained by the emergence of a youngmore » quasar from an early, dust-enshrouded phase, or by clouds compressed by a blast wave. The age of the starburst component is comparable to estimates of the lifetime of quasars, so if we assume the quasar activity is related to the truncation of the star formation, this object is better explained by the blast wave scenario.« less

Discovery of a z = 0.65 post-starburst BAL quasar in the DES supernova fields

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mudd, Dale; Martini, Paul; Tie, Suk Sien

In this paper, we present the discovery of a z = 0.65 low-ionization broad absorption line (LoBAL) quasar in a post-starburst galaxy in data from the Dark Energy Survey (DES) and spectroscopy from the Australian Dark Energy Survey (OzDES). LoBAL quasars are a minority of all BALs, and rarer still is that this object also exhibits broad Fe ii (an FeLoBAL) and Balmer absorption. This is the first BAL quasar that has signatures of recently truncated star formation, which we estimate ended about 40 Myr ago. The characteristic signatures of an FeLoBAL require high column densities, which could be explainedmore » by the emergence of a young quasar from an early, dust-enshrouded phase, or by clouds compressed by a blast wave. Finally, the age of the starburst component is comparable to estimates of the lifetime of quasars, so if we assume the quasar activity is related to the truncation of the star formation, this object is better explained by the blast wave scenario.« less

Numerical simulation of the fluid-structure interaction between air blast waves and soil structure

NASA Astrophysics Data System (ADS)

Umar, S.; Risby, M. S.; Albert, A. Luthfi; Norazman, M.; Ariffin, I.; Alias, Y. Muhamad

2014-03-01

Normally, an explosion threat on free field especially from high explosives is very dangerous due to the ground shocks generated that have high impulsive load. Nowadays, explosion threats do not only occur in the battlefield, but also in industries and urban areas. In industries such as oil and gas, explosion threats may occur on logistic transportation, maintenance, production, and distribution pipeline that are located underground to supply crude oil. Therefore, the appropriate blast resistances are a priority requirement that can be obtained through an assessment on the structural response, material strength and impact pattern of material due to ground shock. A highly impulsive load from ground shocks is a dynamic load due to its loading time which is faster than ground response time. Of late, almost all blast studies consider and analyze the ground shock in the fluid-structure interaction (FSI) because of its influence on the propagation and interaction of ground shock. Furthermore, analysis in the FSI integrates action of ground shock and reaction of ground on calculations of velocity, pressure and force. Therefore, this integration of the FSI has the capability to deliver the ground shock analysis on simulation to be closer to experimental investigation results. In this study, the FSI was implemented on AUTODYN computer code by using Euler-Godunov and the arbitrary Lagrangian-Eulerian (ALE). Euler-Godunov has the capability to deliver a structural computation on a 3D analysis, while ALE delivers an arbitrary calculation that is appropriate for a FSI analysis. In addition, ALE scheme delivers fine approach on little deformation analysis with an arbitrary motion, while the Euler-Godunov scheme delivers fine approach on a large deformation analysis. An integrated scheme based on Euler-Godunov and the arbitrary Lagrangian-Eulerian allows us to analyze the blast propagation waves and structural interaction simultaneously.

A geophysical shock and air blast simulator at the National Ignition Facility

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fournier, K. B.; Brown, C. G.; May, M. J.

2014-09-15

The energy partitioning energy coupling experiments at the National Ignition Facility (NIF) have been designed to measure simultaneously the coupling of energy from a laser-driven target into both ground shock and air blast overpressure to nearby media. The source target for the experiment is positioned at a known height above the ground-surface simulant and is heated by four beams from the NIF. The resulting target energy density and specific energy are equal to those of a low-yield nuclear device. The ground-shock stress waves and atmospheric overpressure waveforms that result in our test system are hydrodynamically scaled analogs of full-scale seismicmore » and air blast phenomena. This report summarizes the development of the platform, the simulations, and calculations that underpin the physics measurements that are being made, and finally the data that were measured. Agreement between the data and simulation of the order of a factor of two to three is seen for air blast quantities such as peak overpressure. Historical underground test data for seismic phenomena measured sensor displacements; we measure the stresses generated in our ground-surrogate medium. We find factors-of-a-few agreement between our measured peak stresses and predictions with modern geophysical computer codes.« less

A geophysical shock and air blast simulator at the National Ignition Facility

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fournier, K. B.; Brown, C. G.; May, M. J.

2014-09-01

The energy partitioning energy coupling experiments at the National Ignition Facility (NIF) have been designed to measure simultaneously the coupling of energy from a laser-driven target into both ground shock and air blast overpressure to nearby media. The source target for the experiment is positioned at a known height above the ground-surface simulant and is heated by four beams from the NIF. The resulting target energy density and specific energy are equal to those of a low-yield nuclear device. The ground-shock stress waves and atmospheric overpressure waveforms that result in our test system are hydrodynamically scaled analogs of full-scale seismicmore » and air blast phenomena. This report summarizes the development of the platform, the simulations, and calculations that underpin the physics measurements that are being made, and finally the data that were measured. Agreement between the data and simulation of the order of a factor of two to three is seen for air blast quantities such as peak overpressure. Historical underground test data for seismic phenomena measured sensor displacements; we measure the stresses generated in our ground-surrogate medium. We find factors-of-a-few agreement between our measured peak stresses and predictions with modern geophysical computer codes.« less

Explosion Source Similarity Analysis via SVD

NASA Astrophysics Data System (ADS)

Yedlin, Matthew; Ben Horin, Yochai; Margrave, Gary

2016-04-01

An important seismological ingredient for establishing a regional seismic nuclear discriminant is the similarity analysis of a sequence of explosion sources. To investigate source similarity, we are fortunate to have access to a sequence of 1805 three-component recordings of quarry blasts, shot from March 2002 to January 2015. The centroid of these blasts has an estimated location 36.3E and 29.9N. All blasts were detonated by JPMC (Jordan Phosphate Mines Co.) All data were recorded at the Israeli NDC, HFRI, located at 30.03N and 35.03E. Data were first winnowed based on the distribution of maximum amplitudes in the neighborhood of the P-wave arrival. The winnowed data were then detrended using the algorithm of Cleveland et al (1990). The detrended data were bandpass filtered between .1 to 12 Hz using an eighth order Butterworth filter. Finally, data were sorted based on maximum trace amplitude. Two similarity analysis approaches were used. First, for each component, the entire suite of traces was decomposed into its eigenvector representation, by employing singular-valued decomposition (SVD). The data were then reconstructed using 10 percent of the singular values, with the resulting enhancement of the S-wave and surface wave arrivals. The results of this first method are then compared to the second analysis method based on the eigenface decomposition analysis of Turk and Pentland (1991). While both methods yield similar results in enhancement of data arrivals and reduction of data redundancy, more analysis is required to calibrate the recorded data to charge size, a quantity that was not available for the current study. References Cleveland, R. B., Cleveland, W. S., McRae, J. E., and Terpenning, I., Stl: A seasonal-trend decomposition procedure based on loess, Journal of Official Statistics, 6, No. 1, 3-73, 1990. Turk, M. and Pentland, A., Eigenfaces for recognition. Journal of cognitive neuroscience, 3(1), 71-86, 1991.

40 CFR 63.1541 - Applicability.

Code of Federal Regulations, 2011 CFR

2011-07-01

... subpart apply to the following affected sources at primary lead smelters: sinter machine, blast furnace... (Incorporations by reference), and § 63.15 (Availability of information confidentiality). The following sections...

Blasting response of the Eiffel Tower

NASA Astrophysics Data System (ADS)

Horlyck, Lachlan; Hayes, Kieran; Caetano, Ryan; Tahmasebinia, Faham; Ansourian, Peter; Alonso-Marroquin, Fernando

2016-08-01

A finite element model of the Eiffel Tower was constructed using Strand7 software. The model replicates the existing tower, with dimensions justified through the use of original design drawings. A static and dynamic analysis was conducted to determine the actions of the tower under permanent, imposed and wind loadings, as well as under blast pressure loads and earthquake loads due to an explosion. It was observed that the tower utilises the full axial capacity of individual members by acting as a `truss of trusses'. As such, permanent and imposed loads are efficiently transferred to the primary columns through compression, while wind loads induce tensile forces in the windward legs and compressive forces in the leeward. Under blast loading, the tower experienced both ground vibrations and blast pressures. Ground vibrations induced a negligibly small earthquake loading into the structure which was ignored in subsequent analyses. The blast pressure was significant, and a dynamic analysis of this revealed that further research is required into the damping qualities of the structure due to soil and mechanical properties. In the worst case scenario, the blast was assumed to completely destroy several members in the adjacent leg. Despite this weakened condition, it was observed that the tower would still be able to sustain static loads, at least for enough time for occupant evacuation. Further, an optimised design revealed the structure was structurally sound under a 46% reduction of the metal tower's mass.

Analysis of Otologic Injuries Due to Blast Trauma by Handmade Explosives

PubMed Central

Aslıer, Mustafa; Aslıer, Nesibe Gül Yüksel

2017-01-01

Objective The aim of this study is to identify the otologic injuries due to handmade explosive-welded blast travma in the law enforcement officers during the combat operations in the curfew security region and to specify the disorders that Otolaryngology and Head Neck Surgery (OHNS) physicians can face during such operations. Methods Medical records of patients in law enforcement who were initially treated by OHNS physicians of Silopi State Hospital during combat operations, between December 14, 2015 and January 15, 2016 were reviewed. Twenty-five patients with otologic injuries due to blast trauma were included in the study. Trauma characteristics, physical examination findings, and beginning treatments were identified. Results Primary blast injury (PBI) was identified as the major disorder in all 24 cases. Tinnitus and hearing loss were the most frequent complaints. In physical examination, tympanic membrane perforations were found in four ears of three patients. Oral methylprednisolone in decreasing doses for 10 days was commenced as an initial treatment in patients with PBI. Secondary blast injury presented in the form of soft tissue damage in the auricular helix due to shrapnel pieces in one patient and a minor surgery was performed. Conclusion Otologic injuries due to blast trauma may often develop during this type of combat operations. Otologic symptoms should be checked, otoscopic examination should be performed, and patients should consult OHNS physicians as soon as possible after trauma. PMID:29392057

Analysis of Otologic Injuries Due to Blast Trauma by Handmade Explosives.

PubMed

Aslıer, Mustafa; Aslıer, Nesibe Gül Yüksel

2017-06-01

The aim of this study is to identify the otologic injuries due to handmade explosive-welded blast travma in the law enforcement officers during the combat operations in the curfew security region and to specify the disorders that Otolaryngology and Head Neck Surgery (OHNS) physicians can face during such operations. Medical records of patients in law enforcement who were initially treated by OHNS physicians of Silopi State Hospital during combat operations, between December 14, 2015 and January 15, 2016 were reviewed. Twenty-five patients with otologic injuries due to blast trauma were included in the study. Trauma characteristics, physical examination findings, and beginning treatments were identified. Primary blast injury (PBI) was identified as the major disorder in all 24 cases. Tinnitus and hearing loss were the most frequent complaints. In physical examination, tympanic membrane perforations were found in four ears of three patients. Oral methylprednisolone in decreasing doses for 10 days was commenced as an initial treatment in patients with PBI. Secondary blast injury presented in the form of soft tissue damage in the auricular helix due to shrapnel pieces in one patient and a minor surgery was performed. Otologic injuries due to blast trauma may often develop during this type of combat operations. Otologic symptoms should be checked, otoscopic examination should be performed, and patients should consult OHNS physicians as soon as possible after trauma.

BLAST: The Balloon-Borne Large Aperture Submillimeter Telescope

NASA Technical Reports Server (NTRS)

Devlin, Mark; Ade, Peter; Bock, Jamie; Dicker, Simon; Griffin, Matt; Gunderson, Josh; Halpern, Mark; Hargrave, Peter; Hughes, David; Klein, Jeff

2004-01-01

BLAST is the Balloon-borne Large-Aperture Sub-millimeter Telescope. It will fly from a Long Duration Balloon (LDB) platform from Antarctica. The telescope design incorporates a 2 m primary mirror with large-format bolometer arrays operating at 250, 350 and 500 microns. By providing the first sensitive large-area (10 sq. deg.) sub-mm surveys at these wavelengths, BLAST will address some of the most important galactic and cosmological questions regarding the formation and evolution of stars, galaxies and clusters. Galactic and extragalactic BLAST surveys will: (1) identify large numbers of high-redshift galaxies; (2) measure photometric redshifts, rest-frame FIR luminosities and star formation rates thereby constraining the evolutionary history of the galaxies that produce the FIR and sub-mm background; (3) measure cold pre-stellar sources associated with the earliest stages of star and planet formation; (4) make high-resolution maps of diffuse galactic emission over a wide range of galactic latitudes. In addition to achieving the above scientific goals, the exciting legacy of the BLAST LDB experiment will be a catalogue of 3000-5000 extragalactic sub-mm sources and a 100 sq. deg. sub-mm galactic plane survey. Multi-frequency follow-up observations from SIRTF, ASTRO-F, and Herschel, together with spectroscopic observations and sub-arcsecond imaging from ALMA are essential to understand the physical nature of the BLAST sources.

Shear velocity and intrinsic Q structure of the shallow crust in southeastern New England from Rg wave dispersion

NASA Astrophysics Data System (ADS)

Saikia, Chandan K.; Kafka, Alan L.; Gnewuch, Scott C.; McTigue, John W.

1990-06-01

In this study, we analyzed 0.5-2.0 s period Rayleigh waves (Rg) generated by quarry and construction blasting in southern New England (CNE). We investigated group velocity dispersion and attenuation of the observed Rg waves. The paths crossing the Hartford Rift basin (HRB) show an obvious correlation between geology and Rg dispersion. The entire region in the southeastern New England comprising a wide range of geological structures and rock types from the Bronson Hill Anticlinorium to the Avalonian Terrane can be represented as one dispersion region. Therefore the relationship between lateral changes in geologic structures mapped on the surface and Rg dispersion is not as straightforward as might be expected for a best fitting flat-layered model of the shallow crust. The shear wave velocities appear to vary between 2.55 and 3.63 km/s within the upper 2.5 km except for the central HRB where the variation is between 2.12 and 2.7 km/s. Intrinsic Q structure is considered to be the primary means for the loss of energy in the shallow crust and was analyzed by modelling the waveforms of several of the observed seismograms. For this aspect of our study, we used a modal summation of Rayleigh waves assuming a far-field radiation approximation. The observed seismograms were dominated primarily by contributions from the fundamental mode, but higher modes were also included in the synthesis of the waveform. We were unable to model the absolute amplitudes of the waveforms because of the problems with the instrument calibration. It is clear, however, that to predict correct waveforms, the shear wave Q values in the upper few tenths of a kilometer of the crust must be about an order of magnitude smaller than Q values at the depth of 1-3 km which is of order of 100-250.

Assessment of inflammatory response and sequestration of blood iron transferrin complexes in a rat model of lung injury resulting from exposure to low-frequency shock waves.

PubMed

Gorbunov, Nikolai V; McFaul, Steve J; Van Albert, Stephen; Morrissette, Craig; Zaucha, Gary M; Nath, Jayasree

2004-04-01

Impact of air blast overpressure waves (OPW), or shock wave, with the body wall or body armor produces two types of energy waves: high-frequency low-amplitude stress waves and long-duration low-frequency share waves. These types of energy waves are characterized by different mechanisms of primary tissue injury that mostly affect lung. Systemic inflammation and resultant acute respiratory distress syndrome are known major secondary causative agents of delayed multiple organ failure and subsequent death after OPW exposure. However, association of each pattern of the blast OPW-produced energy waves with postexposure inflammatory events has not yet been delineated. The objectives of the present research were a) establishment of a rat model for assessment of the inflammatory response following lung injury produced by exposure to medium-amplitude (approximately 120 kPa) low-frequency (260+/-5 Hz) OPWs; and b) assessment of the dynamics of alteration in polymorphonuclear leukocyte counts and expression of CD11b adhesion molecules on the surface of polymorphonuclear leukocytes and status of iron-transferrin complexes in peripheral blood after OPW exposure. This study focused on the OPW effects at different time periods, using a sequential approach to postexposure events. Lung injury in rat was induced by OPW generated in a laboratory shock tube. Animals were exposed to OPW (at peak overpressure of 118+/-7 kPa) that produced "moderate" lung injury. Military research institute. Twenty-seven CVF Sprague-Dawley rats were subjected to OPW exposures, and 17 sham-treated animals were used as control. Lung tissue and blood samples were collected at 1, 3, 6, 12, and 24 hrs following OPW exposures and compared with samples collected from nonexposed animals. OPW-induced lung injury caused a 2.7-fold increase in the number of circulatory polymorphonuclear leukocytes as early as 1 hr postexposure, which is indicative of mobilization of the pool of marginated polymorphonuclear leukocytes into the free circulation. Polymorphonuclear leukocyte counts increased through the following 3- and 6-hr periods, when they were, respectively, 5-fold and 3.5-fold higher than in controls. These effects were accompanied by a pronounced expression of CD11b in polymorphonuclear leukocytes and tissue sequestration of blood iron-transferrin complexes during the entire 24-hr period of observations. The increase in circulatory polymorphonuclear leukocytes was accompanied by a decrease in iron-transferrin complex concentrations that apparently reflected implication of blood plasma iron in the inflammatory cell response to OPW-induced injury. The observed dynamics in polymorphonuclear leukocyte alterations in peripheral blood after OPW exposure were similar to those found recently in clinical observations of nonpenetrating injury and in animal models of infectious insults. Therefore, our data suggest that the main pattern of proinflammatory alterations in the rat model of lung injury induced by exposure to long-duration shock wave is similar to patterns that are characteristic of major trauma. The data further suggest that the expression of polymorphonuclear leukocyte CD11b and the response of iron-transferrin complex can be considered as potential surrogate markers in blood for systemic alterations following OPW-induced injury and, therefore, warrant further investigation in a human pilot study.

On the propagation and multiple reflections of a blast wave travelling through a dusty gas in a closed box

NASA Astrophysics Data System (ADS)

Lappa, Marcello; Drikakis, Dimitris; Kokkinakis, Ioannis

2017-03-01

This paper concerns the propagation of shock waves in an enclosure filled with dusty gas. The main motivation for this problem is to probe the effect on such dynamics of solid particles dispersed in the fluid medium. This subject, which has attracted so much attention over recent years given its important implications in the study of the structural stability of systems exposed to high-energy internal detonations, is approached here in the framework of a hybrid numerical two-way coupled Eulerian-Lagrangian methodology. In particular, insights are sought by considering a relatively simple archetypal setting corresponding to a shock wave originating from a small spherical region initialized on the basis of available analytic solutions. The response of the system is explored numerically with respect to several parameters, including the blast intensity (via the related value of the initial shock Mach number), the solid mass fraction (mass load), and the particle size (Stokes number). Results are presented in terms of pressure-load diagrams. Beyond practical applications, it is shown that a kaleidoscope of fascinating patterns is produced by the "triadic" relationships among multiple shock reflection events and particle-fluid and particle-wall interaction dynamics. These would be of great interest to researchers and scientists interested in fundamental problems relating to the general theory of pattern formation in complex nonlinear multiphase systems.

Directed blasts and blast-generated pyroclastic density currents: a comparison of the Bezymianny 1956, Mount St Helens 1980, and Soufrière Hills, Montserrat 1997 eruptions and deposits

USGS Publications Warehouse

Belousov, Alexander; Voight, Barry; Belousova, Marina

2007-01-01

We compare eruptive dynamics, effects and deposits of the Bezymianny 1956 (BZ), Mount St Helens 1980 (MSH), and Soufrière Hills volcano, Montserrat 1997 (SHV) eruptions, the key events of which included powerful directed blasts. Each blast subsequently generated a high-energy stratified pyroclastic density current (PDC) with a high speed at onset. The blasts were triggered by rapid unloading of an extruding or intruding shallow magma body (lava dome and/or cryptodome) of andesitic or dacitic composition. The unloading was caused by sector failures of the volcanic edifices, with respective volumes for BZ, MSH, and SHV c. 0.5, 2.5, and 0.05 km3 . The blasts devastated approximately elliptical areas, axial directions of which coincided with the directions of sector failures. We separate the transient directed blast phenomenon into three main parts, the burst phase, the collapse phase, and the PDC phase. In the burst phase the pressurized mixture is driven by initial kinetic energy and expands rapidly into the atmosphere, with much of the expansion having an initially lateral component. The erupted material fails to mix with sufficient air to form a buoyant column, but in the collapse phase, falls beyond the source as an inclined fountain, and thereafter generates a PDC moving parallel to the ground surface. It is possible for the burst phase to comprise an overpressured jet, which requires injection of momentum from an orifice; however some exploding sources may have different geometry and a jet is not necessarily formed. A major unresolved question is whether the preponderance of strong damage observed in the volcanic blasts should be attributed to shock waves within an overpressured jet, or alternatively to dynamic pressures and shocks within the energetic collapse and PDC phases. Internal shock structures related to unsteady flow and compressibility effects can occur in each phase. We withhold judgment about published shock models as a primary explanation for the damage sustained at MSH until modern 3D numerical modeling is accomplished, but argue that much of the damage observed in directed blasts can be reasonably interpreted to have been caused by high dynamic pressures and clast impact loading by an inclined collapsing fountain and stratified PDC. This view is reinforced by recent modeling cited for SHV. In distal and peripheral regions, solids concentration, maximum particle size, current speed, and dynamic pressure are diminished, resulting in lesser damage and enhanced influence by local topography on the PDC. Despite the different scales of the blasts (devastated areas were respectively 500, 600, and >10 km2 for BZ, MSH, and SHV), and some complexity involving retrogressive slide blocks and clusters of explosions, their pyroclastic deposits demonstrate strong similarity. Juvenile material composes >50% of the deposits, implying for the blasts a dominantly magmatic mechanism although hydrothermal explosions also occurred. The character of the magma fragmented by explosions (highly viscous, phenocryst-rich, variable microlite content) determined the bimodal distributions of juvenile clast density and vesicularity. Thickness of the deposits fluctuates in proximal areas but in general decreases with distance from the crater, and laterally from the axial region. The proximal stratigraphy of the blast deposits comprises four layers named A, B, C, D from bottom to top. Layer A is represented by very poorly sorted debris with admixtures of vegetation and soil, with a strongly erosive ground contact; its appearance varies at different sites due to different ground conditions at the time of the blasts. The layer reflects intense turbulent boundary shear between the basal part of the energetic head of the PDC and the substrate. Layer B exhibits relatively well-sorted fines depleted debris with some charred plant fragments; its deposition occurred by rapid suspension sedimentation in rapidly waning, high-concentration conditions. Layer C is mainly a poorly sorted massive layer enriched by fines with its uppermost part laminated, created by rapid sedimentation under moderate-concentration, weakly tractive conditions, with the uppermost laminated part reflecting a dilute depositional regime with grain-by-grain traction deposition. By analogy to laboratory experiments, mixing at the flow head of the PDC created a turbulent dilute wake above the body of a gravity current, with layer B deposited by the flow body and layer C by the wake. The uppermost layer D of fines and accretionary lapilli is an ash fallout deposit of the finest particles from the high-rising buoyant thermal plume derived from the sediment-depleted pyroclastic density current. The strong similarity among these eruptions and their deposits suggests that these cases represent similar source, transport and depositional phenomena.

Porcine head response to blast.

PubMed

Shridharani, Jay K; Wood, Garrett W; Panzer, Matthew B; Capehart, Bruce P; Nyein, Michelle K; Radovitzky, Raul A; Bass, Cameron R 'dale'

2012-01-01

Recent studies have shown an increase in the frequency of traumatic brain injuries related to blast exposure. However, the mechanisms that cause blast neurotrauma are unknown. Blast neurotrauma research using computational models has been one method to elucidate that response of the brain in blast, and to identify possible mechanical correlates of injury. However, model validation against experimental data is required to ensure that the model output is representative of in vivo biomechanical response. This study exposes porcine subjects to primary blast overpressures generated using a compressed-gas shock tube. Shock tube blasts were directed to the unprotected head of each animal while the lungs and thorax were protected using ballistic protective vests similar to those employed in theater. The test conditions ranged from 110 to 740 kPa peak incident overpressure with scaled durations from 1.3 to 6.9 ms and correspond approximately with a 50% injury risk for brain bleeding and apnea in a ferret model scaled to porcine exposure. Instrumentation was placed on the porcine head to measure bulk acceleration, pressure at the surface of the head, and pressure inside the cranial cavity. Immediately after the blast, 5 of the 20 animals tested were apneic. Three subjects recovered without intervention within 30 s and the remaining two recovered within 8 min following respiratory assistance and administration of the respiratory stimulant doxapram. Gross examination of the brain revealed no indication of bleeding. Intracranial pressures ranged from 80 to 390 kPa as a result of the blast and were notably lower than the shock tube reflected pressures of 300-2830 kPa, indicating pressure attenuation by the skull up to a factor of 8.4. Peak head accelerations were measured from 385 to 3845 G's and were well correlated with peak incident overpressure (R(2) = 0.90). One SD corridors for the surface pressure, intracranial pressure (ICP), and head acceleration are presented to provide experimental data for computer model validation.

Porcine Head Response to Blast

PubMed Central

Shridharani, Jay K.; Wood, Garrett W.; Panzer, Matthew B.; Capehart, Bruce P.; Nyein, Michelle K.; Radovitzky, Raul A.; Bass, Cameron R. ‘Dale’

2012-01-01

Recent studies have shown an increase in the frequency of traumatic brain injuries related to blast exposure. However, the mechanisms that cause blast neurotrauma are unknown. Blast neurotrauma research using computational models has been one method to elucidate that response of the brain in blast, and to identify possible mechanical correlates of injury. However, model validation against experimental data is required to ensure that the model output is representative of in vivo biomechanical response. This study exposes porcine subjects to primary blast overpressures generated using a compressed-gas shock tube. Shock tube blasts were directed to the unprotected head of each animal while the lungs and thorax were protected using ballistic protective vests similar to those employed in theater. The test conditions ranged from 110 to 740 kPa peak incident overpressure with scaled durations from 1.3 to 6.9 ms and correspond approximately with a 50% injury risk for brain bleeding and apnea in a ferret model scaled to porcine exposure. Instrumentation was placed on the porcine head to measure bulk acceleration, pressure at the surface of the head, and pressure inside the cranial cavity. Immediately after the blast, 5 of the 20 animals tested were apneic. Three subjects recovered without intervention within 30 s and the remaining two recovered within 8 min following respiratory assistance and administration of the respiratory stimulant doxapram. Gross examination of the brain revealed no indication of bleeding. Intracranial pressures ranged from 80 to 390 kPa as a result of the blast and were notably lower than the shock tube reflected pressures of 300–2830 kPa, indicating pressure attenuation by the skull up to a factor of 8.4. Peak head accelerations were measured from 385 to 3845 G’s and were well correlated with peak incident overpressure (R2 = 0.90). One SD corridors for the surface pressure, intracranial pressure (ICP), and head acceleration are presented to provide experimental data for computer model validation. PMID:22586417

The Threats to Survival in a Nuclear Environment.

DTIC Science & Technology

1987-05-01

second threat to survival in a nuclear attack is the blast or shock wave. Deen and Browning, in How to Survive a Nuclear Disaster , state, "It has been... Nuclear Disaster . Piscataway, NJ: A Grayson-Russell Book, New Century P’u-S1Tshers, 198t. 1S. Martin, Thomas 1., Jr. and Latham, Ronald C. Strategqy

A mouse model of ocular blast injury that induces closed globe anterior and posterior pole damage

PubMed Central

Hines-Beard, Jessica; Marchetta, Jeffrey; Gordon, Sarah; Chaum, Edward; Geisert, Eldon E.; Rex, Tonia S.

2012-01-01

We developed and characterized a mouse model of primary ocular blast injury. The device consists of: a pressurized air tank attached to a regulated paintball gun with a machined barrel; a chamber that protects the mouse from direct injury and recoil, while exposing the eye; and a secure platform that enables fine, controlled movement of the chamber in relation to the barrel. Expected pressures were calculated and the optimal pressure transducer, based on the predicted pressures, was positioned to measure output pressures at the location where the mouse eye would be placed. Mice were exposed to one of three blast pressures (23.6, 26.4, or 30.4psi). Gross pathology, intraocular pressure, optical coherence tomography, and visual acuity were assessed 0, 3, 7, 14, and 28 days after exposure. Contralateral eyes and non-blast exposed mice were used as controls. We detected increased damage with increased pressures and a shift in the damage profile over time. Gross pathology included corneal edema, corneal abrasions, and optic nerve avulsion. Retinal damage was detected by optical coherence tomography and a deficit in visual acuity was detected by optokinetics. Our findings are comparable to those identified in Veterans of the recent wars with closed eye injuries as a result of blast exposure. In summary, this is a relatively simple system that creates injuries with features similar to those seen in patients with ocular blast trauma. This is an important new model for testing the short-term and long-term spectrum of closed globe blast injuries and potential therapeutic interventions. PMID:22504073

Prospectively assessed clinical outcomes in concussive blast vs nonblast traumatic brain injury among evacuated US military personnel.

PubMed

Mac Donald, Christine L; Johnson, Ann M; Wierzechowski, Linda; Kassner, Elizabeth; Stewart, Theresa; Nelson, Elliot C; Werner, Nicole J; Zonies, David; Oh, John; Fang, Raymond; Brody, David L

2014-08-01

Blast injury has been identified as the signature injury in the conflicts in Iraq and Afghanistan. However it remains to be determined whether fundamental differences may exist between blast-related traumatic brain injury (TBI) and TBI due to other mechanisms. To determine similarities and differences between clinical outcomes in US military personnel with blast-related vs. non-blast-related concussive TBI and to identify the specific domains of impairment that best correlate with overall disability. Prospective cohort study involving active duty US Military personnel evacuated from Iraq or Afghanistan to Landstuhl Regional Medical Center, in Landstuhl, Germany. Four groups of participants were enrolled from 2010 to 2013: (1) blast plus impact complex TBI (n=53), (2) non-blast related TBI with injury due to other mechanisms (n=29), (3) blast-exposed controls evacuated for other medical reasons (n=27) (4) non-blast-exposed controls evacuated for other medical reasons (n=69). All patients with TBI met Department of Defense criteria for concussive (mild) TBI. The study participants were evaluated 6-12 months after injury at Washington University in St Louis. In total, 255 subjects were enrolled in the study, and 183 participated in follow-up evaluations, 5 of whom were disqualified. In-person clinical examinations included evaluation for overall disability, a standardized neurological exam, headache questionnaires, neuropsychological test battery, combat exposure and alcohol use surveys, and structured interview evaluations for post-traumatic stress disorder (PTSD) and depression. Global outcomes, headache severity, neuropsychological performance, and surprisingly even PTSD severity and depression were indistinguishable between the two TBI groups, independent of mechanism of injury. Both TBI groups had higher rates of moderate to severe overall disability than the respective control groups: 41/53 (77%) of blast plus impact TBI and 23/29 (79%) of nonblast TBI vs. 16/27 (59%) of blast-exposed controls and 28/69 (41%) of non-blast-exposed controls. In addition, blast-exposed controls had worse headaches and more severe PTSD than non-blast-exposed controls. Self-reported combat exposure intensity was higher in the blast plus impact TBI group than in nonblast TBI group and was higher in blast-exposed controls than in non-blast-exposed controls. However, combat exposure intensity did not correlate with PTSD severity in the TBI groups, but a modest positive correlation was observed in the controls. Overall outcomes were most strongly correlated with depression, headache severity, and number of abnormalities on neuropsychological testing. However a substantial fraction of the variance in overall outcome was not explained by any of the assessed measures. One potential interpretation of these results is that TBI itself, independent of injury mechanism and combat exposure intensity, is a primary driver of adverse outcomes. Many other important factors may be as yet unmeasured, and adverse outcomes following war-time injuries are difficult to fully explain. clinicaltrials.gov Identifier: NCT01313130.

Numerical Simulation of Bolide Entry with Ground Footprint Prediction

NASA Technical Reports Server (NTRS)

Aftosmis, Michael J.; Nemec, Marian; Mathias, Donovan L.; Berger, Marsha J.

2016-01-01

As they decelerate through the atmosphere, meteors deposit mass, momentum and energy into the surrounding air at tremendous rates. Trauma from the entry of such bolides produces strong blast waves that can propagate hundreds of kilometers and cause substantial terrestrial damage even when no ground impact occurs. We present a new simulation technique for airburst blast prediction using a fully-conservative, Cartesian mesh, finite-volume solver and investigate the ability of this method to model far- field propagation over hundreds of kilometers. The work develops mathematical models for the deposition of mass, momentum and energy into the atmosphere and presents verification and validation through canonical problems and the comparison of surface overpressures, and blast arrival times with actual results in the literature for known bolides. The discussion also examines the effects of various approximations to the physics of bolide entry that can substantially decrease the computational expense of these simulations. We present parametric studies to quantify the influence of entry-angle, burst-height and other parameters on the ground footprint of the airburst, and these values are related to predictions from analytic and handbook-methods.

On the fundamental unsteady fluid dynamics of shock-induced flows through ducts

NASA Astrophysics Data System (ADS)

Mendoza, Nicole Renee

Unsteady shock wave propagation through ducts has many applications, ranging from blast wave shelter design to advanced high-speed propulsion systems. The research objective of this study was improved fundamental understanding of the transient flow structures during unsteady shock wave propagation through rectangular ducts with varying cross-sectional area. This research focused on the fluid dynamics of the unsteady shock-induced flow fields, with an emphasis placed on understanding and characterizing the mechanisms behind flow compression (wave structures), flow induction (via shock waves), and enhanced mixing (via shock-induced viscous shear layers). A theoretical and numerical (CFD) parametric study was performed, in which the effects of these parameters on the unsteady flow fields were examined: incident shock strength, area ratio, and viscous mode (inviscid, laminar, and turbulent). Two geometries were considered: the backward-facing step (BFS) geometry, which provided a benchmark and conceptual framework, and the splitter plate (SP) geometry, which was a canonical representation of the engine flow path. The theoretical analysis was inviscid, quasi-1 D and quasi-steady; and the computational analysis was fully 2D, time-accurate, and VISCOUS. The theory provided the wave patterns and primary wave strengths for the BFS geometry, and the simulations verified the wave pattems and quantified the effects of geometry and viscosity. It was shown that the theoretical wave patterns on the BFS geometry can be used to systematically analyze the transient, 20, viscous flows on the SP geometry. This work also highlighted the importance and the role of oscillating shock and expansion waves in the development of these unsteady flows. The potential for both upstream and downstream flow induction was addressed. Positive upstream flow induction was not found in this study due to the persistent formation of an upstream-moving shock wave. Enhanced mixing was addressed by examining the evolution of the unsteady shear layer, its instability, and their effects on the flow field. The instability always appeared after the reflected shock interaction, and was exacerbated in the laminar cases and damped out in the turbulent cases. This research provided new understanding of the long-term evolution of these confined flows. Lastly, the turbulent work is one of the few turbulent studies on these flows.

Combined Effects of Primary and Tertiary Blast on Rat Brain: Characterization of a Model of Blast-induced Mild Traumatic Brain Injury

DTIC Science & Technology

2013-03-01

membranes and blocked with 4% non- fat dry milk for 1 h at room temperature. The blots were incubated with anti-mouse MPO monoclonal antibody (1:1000...Arun, M. Valiyaveettil, L. Biggemann, Y. Alamneh, Y. Wei, S. Oguntayo, Y. Wang, J.B. Long, M.P. Nambiar. Modulation of hearing related proteins in...skull with weight drop 30 sec post BOP, N=6-7 rats/gp) Fig 12. Changes in the neuron-specific cytoskeletal protein Microtubule-associated protein

Influence of bubble size and thermal dissipation on compressive wave attenuation in liquid foams

NASA Astrophysics Data System (ADS)

Monloubou, M.; Saint-Jalmes, A.; Dollet, B.; Cantat, I.

2015-11-01

Acoustic or blast wave absorption by liquid foams is especially efficient and bubble size or liquid fraction optimization is an important challenge in this context. A resonant behavior of foams has recently been observed, but the main local dissipative process is still unknown. In this paper, we evidence the thermal origin of the dissipation, with an optimal bubble size close to the thermal boundary layer thickness. Using a shock tube, we produce typical pressure variation at time scales of the order of the millisecond, which propagates in the foam in linear and slightly nonlinear regimes.

The Air Blast Wave from a Nuclear Explosion

NASA Astrophysics Data System (ADS)

Reines, Frederick

The sudden, large scale release of energy in the explosion of a nuclear bomb in air gives rise, in addition to nuclear emanations such as neutrons and gamma rays, to an extremely hot, rapidly expanding mass of air.** The rapidly expanding air mass has an initial temperature in the vicinity of a few hundred thousand degrees and for this reason it glows in its early stages with an intensity of many suns. It is important that the energy density in this initial "ball of fire" is of the order of 3 × 103 times that found in a detonating piece of TNT and hence that the initial stages of the large scale air motion produced by a nuclear explosion has no counterpart in an ordinary. H. E. explosion. Further, the relatively low temperatures ˜2,000°C associated with the initial stages of an H. E. detonation implies that the thermal radiation which it emits is a relatively insignificant fraction of the total energy involves. This point is made more striking when it is remembered that the thermal energy emitted by a hot object varies directly with the temperature in the Rayleigh Jeans region appropriate to the present discussion. The expansion of the air mass heated by the nuclear reaction produces, in qualitatively the same manner as in an H.E. explosion or the bursting of a high pressure balloon, an intense sharp pressure pulse, a shock wave, in the atmosphere. As the pressure pulse spreads outward it weakens due to the combined effects of divergence and the thermodynamically irreversible nature of the shock wave. The air comprising such a pressure pulse or blast wave moves first radially outward and then back towards the center as the blast wave passes. Since a permanent outward displacement of an infinite mass of air would require unlimited energy, the net outward displacement of the air distant from an explosion must approach zero with increasing distance. As the distance from the explosion is diminished the net outward displacement due to irreversible shock heating of the air increases and in the limit of small distances and increasingly strong shocks the net outward displacement of the shocked air is equal to the maximum outward displacement. These statements are applicable for short times of the order of seconds following the explosion since the heated air l behind by the shock wave will rise. The pressures and air mass motions associated with the rise of the atomic cloud are relatively unimportant in the free air pressure ranges from 2-15 psi for bomb yields under 100 kilotons (KT)…

Effects of UGTs on the ionosphere

NASA Astrophysics Data System (ADS)

Argo, P. E.; Fitzgerald, T. J.

The processes that propagate local effects of underground nuclear tests from the ground into the upper atmosphere, and produce a detectable signal in the ionosphere are described. Initially, the blast wave from a underground test (UGT) radially expands, until it reaches the surface of the earth. The wave is both reflected and transmitted at this sharp discontinuity in propagation media. Tne reflected wave combines with the incident wave to form an 'Airy surface,' at which very strong ripping forces tear the earth apart. This broken region is called the 'spat zone,' and is launched into ballistic motion. The resultant ground motion launches an acoustical wave into the atmosphere. This acoustic wave, with overpressures of a few tenths of one percent, propagates upwards at the speed of sound. Assuming purely linear propagation, the path of the acoustic energy can be tracked using raytracing models. Most of the wave energy, which is radiated nearly vertically, tends to propagate into the upper atmosphere, while wave energy radiated at angles greater than about 30 degrees to the vertical will be reflected back to earth and is probably what is seen by most infrasonde measurements.

Effect of Blast Injury on Auditory Localization in Military Service Members.

PubMed

Kubli, Lina R; Brungart, Douglas; Northern, Jerry

Among the many advantages of binaural hearing are the abilities to localize sounds in space and to attend to one sound in the presence of many sounds. Binaural hearing provides benefits for all listeners, but it may be especially critical for military personnel who must maintain situational awareness in complex tactical environments with multiple speech and noise sources. There is concern that Military Service Members who have been exposed to one or more high-intensity blasts during their tour of duty may have difficulty with binaural and spatial ability due to degradation in auditory and cognitive processes. The primary objective of this study was to assess the ability of blast-exposed Military Service Members to localize speech sounds in quiet and in multisource environments with one or two competing talkers. Participants were presented with one, two, or three topic-related (e.g., sports, food, travel) sentences under headphones and required to attend to, and then locate the source of, the sentence pertaining to a prespecified target topic within a virtual space. The listener's head position was monitored by a head-mounted tracking device that continuously updated the apparent spatial location of the target and competing speech sounds as the subject turned within the virtual space. Measurements of auditory localization ability included mean absolute error in locating the source of the target sentence, the time it took to locate the target sentence within 30 degrees, target/competitor confusion errors, response time, and cumulative head motion. Twenty-one blast-exposed Active-Duty or Veteran Military Service Members (blast-exposed group) and 33 non-blast-exposed Service Members and beneficiaries (control group) were evaluated. In general, the blast-exposed group performed as well as the control group if the task involved localizing the source of a single speech target. However, if the task involved two or three simultaneous talkers, localization ability was compromised for some participants in the blast-exposed group. Blast-exposed participants were less accurate in their localization responses and required more exploratory head movements to find the location of the target talker. Results suggest that blast-exposed participants have more difficulty than non-blast-exposed participants in localizing sounds in complex acoustic environments. This apparent deficit in spatial hearing ability highlights the need to develop new diagnostic tests using complex listening tasks that involve multiple sound sources that require speech segregation and comprehension.

On the Unsteady Shock Wave Interaction with a Backward-Facing Step: Viscous Analysis

NASA Astrophysics Data System (ADS)

Mendoza, N.; Bowersox, R. D. W.

Unsteady shock propagation through ducts with varying cross-sectional area occurs in many engineering applications, such as explosions in underground tunnels, blast shelter design, engine exhaust systems, and high-speed propulsion systems. These complex, transient flows are rich in fundamental fluid-dynamic phenomena and are excellent testbeds for improving our understanding of unsteady fluid dynamics

Finite size of hadrons and Bose-Einstein correlations in pp collisions at 7 TeV

NASA Astrophysics Data System (ADS)

Bialas, Andrzej; Florkowski, Wojciech; Zalewski, Kacper

2015-09-01

Space-time correlations between produced particles, induced by the composite nature of hadrons, imply specific changes in the properties of the correlation functions for identical particles. The expected magnitude of these effects is evaluated using the recently published blast-wave model analysis of the data for pp collisions at √{ s} = 7 TeV.

Spectral properties of blast-wave models of gamma-ray burst sources

NASA Technical Reports Server (NTRS)

Meszaros, P.; Rees, M. J.; Papathanassiou, H.

1994-01-01

We calculate the spectrum of blast-wave models of gamma-ray burst sources, for various assumptions about the magnetic field density and the relativistic particle acceleration efficiency. For a range of physically plausible models we find that the radiation efficiency is high and leads to nonthermal spectra with breaks at various energies comparable to those observed in the gamma-ray range. Radiation is also predicted at other wavebands, in particular at X-ray, optical/UV, and GeV/TeV energies. We discuss the spectra as a function of duration for three basic types of models, and for cosmological, halo, and galactic disk distances. We also evaluate the gamma-ray fluences and the spectral characteristics for a range of external densities. Impulsive burst models at cosmological distances can satisfy the conventional X-ray paucity constraint S(sub x)/S(sub gamma)less than a few percent over a wide range of durations, but galactic models can do so only for bursts shorter than a few seconds, unless additional assumptions are made. The emissivity is generally larger for bursts in a denser external environment, with the efficiency increasing up to the point where all the energy input is radiated away.

Numerical study of water mitigation effects on blast wave

NASA Astrophysics Data System (ADS)

Cheng, M.; Hung, K. C.; Chong, O. Y.

2005-11-01

The mitigating effect of a water wall on the generation and propagation of blast waves of a nearby explosive has been investigated using a numerical approach. A multimaterial Eulerian finite element technique is used to study the influence of the design parameters, such as the water-to-explosive weight ratio, the water wall thickness, the air-gap and the cover area ratio of water on the effectiveness of the water mitigation concept. In the computational model, the detonation gases are modelled with the standard Jones Wilkins Lee (JWL) equation of state. Water, on the other hand, is treated as a compressible fluid with the Mie Gruneisen equation of state model. The validity of the computational model is checked against a limited amount of available experimental data, and the influence of mesh sizes on the convergence of results is also discussed. From the results of the extensive numerical experiments, it is deduced that firstly, the presence of an air-gap reduces the effectiveness of the water mitigator. Secondly, the higher the water-to-explosive weight ratio, the more significant is the reduction in peak pressure of the explosion. Typically, water-to-explosive weight ratios in the range of 1 3 are found to be most practical.

Experimental study of detonation of large-scale powder-droplet-vapor mixtures

NASA Astrophysics Data System (ADS)

Bai, C.-H.; Wang, Y.; Xue, K.; Wang, L.-F.

2018-05-01

Large-scale experiments were carried out to investigate the detonation performance of a 1600-m3 ternary cloud consisting of aluminum powder, fuel droplets, and vapor, which were dispersed by a central explosive in a cylindrically stratified configuration. High-frame-rate video cameras and pressure gauges were used to analyze the large-scale explosive dispersal of the mixture and the ensuing blast wave generated by the detonation of the cloud. Special attention was focused on the effect of the descending motion of the charge on the detonation performance of the dispersed ternary cloud. The charge was parachuted by an ensemble of apparatus from the designated height in order to achieve the required terminal velocity when the central explosive was detonated. A descending charge with a terminal velocity of 32 m/s produced a cloud with discernably increased concentration compared with that dispersed from a stationary charge, the detonation of which hence generates a significantly enhanced blast wave beyond the scaled distance of 6 m/kg^{1/3}. The results also show the influence of the descending motion of the charge on the jetting phenomenon and the distorted shock front.

Modeling and simulations of radiative blast wave driven Rayleigh-Taylor instability experiments

NASA Astrophysics Data System (ADS)

Shimony, Assaf; Huntington, Channing M.; Trantham, Matthew; Malamud, Guy; Elbaz, Yonatan; Kuranz, Carolyn C.; Drake, R. Paul; Shvarts, Dov

2017-10-01

Recent experiments at the National Ignition Facility measured the growth of Rayleigh-Taylor RT instabilities driven by radiative blast waves, relevant to astrophysics and other HEDP systems. We constructed a new Buoyancy-Drag (BD) model, which accounts for the ablation effect on both bubble and spike. This ablation effect is accounted for by using the potential flow model ]Oron et al PoP 1998], adding another term to the classical BD formalism: βDuA / u , where β the Takabe constant, D the drag term, uA the ablation velocity and uthe instability growth velocity. The model results are compared with the results of experiments and 2D simulations using the CRASH code, with nominal radiation or reduced foam opacity (by a factor of 1000). The ablation constant of the model, βb / s, for the bubble and for the spike fronts, are calibrated using the results of the radiative shock experiments. This work is funded by the Lawrence Livermore National Laboratory under subcontract B614207, and was performed under the auspices of the U.S. Department of Energy by Lawrence Livermore National Laboratory under Contract No. DE-AC52-07NA27344.

Evidence for a Transketolase-Mediated Metabolic Checkpoint Governing Biotrophic Growth in Rice Cells by the Blast Fungus Magnaporthe oryzae

PubMed Central

Fernandez, Jessie; Marroquin-Guzman, Margarita; Wilson, Richard A.

2014-01-01

The blast fungus Magnaporthe oryzae threatens global food security through the widespread destruction of cultivated rice. Foliar infection requires a specialized cell called an appressorium that generates turgor to force a thin penetration hypha through the rice cuticle and into the underlying epidermal cells, where the fungus grows for the first days of infection as a symptomless biotroph. Understanding what controls biotrophic growth could open new avenues for developing sustainable blast intervention programs. Here, using molecular genetics and live-cell imaging, we dismantled M. oryzae glucose-metabolizing pathways to reveal that the transketolase enzyme, encoded by TKL1, plays an essential role in facilitating host colonization during rice blast disease. In the absence of transketolase, Δtkl1 mutant strains formed functional appressoria that penetrated rice cuticles successfully and developed invasive hyphae (IH) in rice cells from primary hyphae. However, Δtkl1 could not undertake sustained biotrophic growth or cell-to-cell movement. Transcript data and observations using fluorescently labeled histone H1:RFP fusion proteins indicated Δtkl1 mutant strains were alive in host cells but were delayed in mitosis. Mitotic delay could be reversed and IH growth restored by the addition of exogenous ATP, a metabolite depleted in Δtkl1 mutant strains. We show that ATP might act via the TOR signaling pathway, and TOR is likely a downstream target of activation for TKL1. TKL1 is also involved in controlling the migration of appressorial nuclei into primary hyphae in host cells. When taken together, our results indicate transketolase has a novel role in mediating - via ATP and TOR signaling - an in planta-specific metabolic checkpoint that controls nuclear migration from appressoria into primary hyphae, prevents mitotic delay in early IH and promotes biotrophic growth. This work thus provides new information about the metabolic strategies employed by M. oryzae to enable rice cell colonization. PMID:25188286

Usage of density analysis based on micro-CT for studying lung injury associated with burn-blast combined injury.

PubMed

Chang, Yang; Zhang, Dong-Hai; Hu, Quan; Liu, Ling-Ying; Yu, Yong-Hui; Chai, Jia-Ke

2018-02-12

Burn-blast combined injury is a kind of injury caused by heat and blast at the same time. The lung injury after burn-blast combined injuries is of primary importance, and investigation of lung injury is needed in the clinical care of patients. Computed tomography (CT) is one of the standard tools used to observe the anatomical basis and pathophysiology of acute lung injury. We applied a method of fast 3D (three-dimensional) reconstruction to calculate the density value of the lung injury by CT analysis. Blast-injury group (BL group), burn-injury group (B group), burn-blast combined injury group (BBL group), and sham control group (C group) were established. Each group had 16 rats. The three-dimensional images of the lung tissue were obtained at 6h, 24h, and 48h according to the CT value. The average density of the whole lung, left lung, and right lung were measured. The lung tissues were paraffin-embedded and HE stained. Smith scoring was performed according to the pathological findings. In the BBL group, the density of the lung tissue was higher than those of the BL group and B group (P<0.01). The lung tissue density values at 24h after injury were higher than those at 6h and 48h after injury (P<0.01). Pathological results confirmed the changes of density analysis of the lung tissue. The results have indicated that density analysis through a CT scan can be used as a way to evaluate lung injury in a burn-blast injury. Copyright © 2018 Elsevier Ltd and ISBI. All rights reserved.

Evaluation of Liquefaction Susceptibility of Clean Sands after Blast Densification

NASA Astrophysics Data System (ADS)

Vega Posada, Carlos Alberto

The effect of earthquakes on infrastructure facilities is an important topic of interest in geotechnical research. A key design issue for such facilities is whether or not liquefaction will occur during an earthquake. The consequences of this type of ground failure are usually severe, resulting in severe damage to a facility and in some cases the loss of human life. One approach to minimize the effect of liquefaction is to improve the ground condition by controlled blasting. The main limitations of the blast densification technique are that the design is mostly empirical and verification studies of densification have resulted in contradictory results in some case studies. In such cases, even though the ground surface settles almost immediately after blasting, common verification tests such as the cone penetration test (CPT), standard penetration test (SPT), and shear wave velocity test (Vs) suggest that the soil mass has not been improved at all. This raises concerns regarding the future performance of the soil and casts doubts on whether or not the improved deposit is still susceptible to liquefaction. In this work, a blast densification program was implemented at the Oakridge Landfill located in Dorchester County, SC, to gain information regarding the condition of a loose sand deposit during and after each blast event. In addition, an extensive laboratory testing program was conducted on reconstituted sand specimens to evaluate the mechanical behavior of saturated and gassy, medium dense sands during monotonic and cyclic loading. The results from the field and laboratory program indicate that gas released during blasting can remain trapped in the soil mass for several years, and this gas greatly affects the mechanical behavior of the sand. Gas greatly increases the liquefaction resistance of the soil. If the gas remains in the sand over the life of a project, then it will maintain this increased resistance to liquefaction, whether or not the penetration resistance increases with time. As part of this work, a methodology based on the critical state concepts was described to quantify the amount of densification needed at a certain project to make the soil more resistant to liquefaction and flow.

A Multiscale Approach to Blast Neurotrauma Modeling: Part I – Development of Novel Test Devices for in vivo and in vitro Blast Injury Models

PubMed Central

Panzer, Matthew B.; Matthews, Kyle A.; Yu, Allen W.; Morrison, Barclay; Meaney, David F.; Bass, Cameron R.

2012-01-01

The loading conditions used in some current in vivo and in vitro blast-induced neurotrauma models may not be representative of real-world blast conditions. To address these limitations, we developed a compressed-gas driven shock tube with different driven lengths that can generate Friedlander-type blasts. The shock tube can generate overpressures up to 650 kPa with durations between 0.3 and 1.1 ms using compressed helium driver gas, and peak overpressures up to 450 kPa with durations between 0.6 and 3 ms using compressed nitrogen. This device is used for short-duration blast overpressure loading for small animal in vivo injury models, and contrasts the more frequently used long duration/high impulse blast overpressures in the literature. We also developed a new apparatus that is used with the shock tube to recreate the in vivo intracranial overpressure response for loading in vitro culture preparations. The receiver device surrounds the culture with materials of similar impedance to facilitate the propagation of a single overpressure pulse through the tissue. This method prevents pressure waves reflecting off the tissue that can cause unrealistic deformation and injury. The receiver performance was characterized using the longest helium-driven shock tube, and produced in-fluid overpressures up to 1500 kPa at the location where a culture would be placed. This response was well correlated with the overpressure conditions from the shock tube (R2 = 0.97). Finite element models of the shock tube and receiver were developed and validated to better elucidate the mechanics of this methodology. A demonstration exposing a culture to the loading conditions created by this system suggest tissue strains less than 5% for all pressure levels simulated, which was well below functional deficit thresholds for strain rates less than 50 s−1. This novel system is not limited to a specific type of culture model and can be modified to reproduce more complex pressure pulses. PMID:22470367

Using Gunshot Detection Systems to Fight Explosive Fishing Practices

NASA Astrophysics Data System (ADS)

Showen, R. L.; Dunson, J. C.; Woodman, G.; Christopher, S.; Wilson, S.

2015-12-01

Blast fishing (using explosives to catch fish) causes extensive damage to coral reefs, especially in the Coral Triangle in Southeast Asia. Subsistence fishermen and larger consortiums, often with criminal links, throw an explosive into a school of fish, killing all sea life within range. This unsustainable practice is becoming more prevalent, and threatens the protein supply of as many as a billion people. Ending blast fishing will require combined technical and societal methods aimed at both deterring the practice, and catching those responsible. Our work aims to significantly improve enforcement. We are re-purposing SST's ShotSpotter gunshot detection system, (trusted and valued by police around the world), substituting hydrophones for the present microphones. Using multilateration and trained human reviewers, the system can give prompt blast alerts, location data, and acoustic waveforms to law enforcement officials. We hope to establish a prototype system in Malaysia in 2015, and have already secured governmental approvals for installation and tests with local law enforcement. The Scubazoo media firm in Malaysia is working with resorts, dive operations, and celebrity sponsors, and is planning to produce videos to illustrate the severity of the problem to both governments and the public. Because there is little hard data concerning the prevalence of blast fishing in either marine protected areas or open waters, the system can also indicate to the world the actual blast rates and patterns of use. The Teng Hoi environmental NGO in Hong Kong showed in 2004 that acoustic waves from typical bombs propagate on the order of 20 km, so an underwater locator system with a small number of sensors can feasibly cover a sizable coral region. Our present plans are to mount sensors on piers, buoys, and boats, but if possible we would also like to integrate with other existing acoustic arrays to strengthen the fight against blast fishing.

Combined inhibition of β-catenin and Bcr-Abl synergistically targets tyrosine kinase inhibitor-resistant blast crisis chronic myeloid leukemia blasts and progenitors in vitro and in vivo.

PubMed

Zhou, H; Mak, P Y; Mu, H; Mak, D H; Zeng, Z; Cortes, J; Liu, Q; Andreeff, M; Carter, B Z

2017-10-01

Tyrosine kinase inhibitor (TKI) resistance and progression to blast crisis (BC), both related to persistent β-catenin activation, remain formidable challenges for chronic myeloid leukemia (CML). We observed overexpression of β-catenin in BC-CML stem/progenitor cells, particularly in granulocyte-macrophage progenitors, and highest among a novel CD34 + CD38 + CD123 hi Tim-3 hi subset as determined by CyTOF analysis. Co-culture with mesenchymal stromal cells (MSCs) induced the expression of β-catenin and its target CD44 in CML cells. A novel Wnt/β-catenin signaling modulator, C82, and nilotinib synergistically killed KBM5 T315I and TKI-resistant primary BC-CML cells with or without BCR-ABL kinase mutations even under leukemia/MSC co-culture conditions. Silencing of β-catenin by short interfering RNA restored sensitivity of primary BCR-ABL T315I/E255V BC-CML cells to nilotinib. Combining the C82 pro-drug, PRI-724, with nilotinib significantly prolonged the survival of NOD/SCID/IL2Rγ null mice injected with primary BCR-ABL T315I/E255V BC-CML cells. The combined treatment selectively targeted CML progenitors and inhibited CD44, c-Myc, survivin, p-CRKL and p-STAT5 expression. In addition, pretreating primary BC-CML cells with C82, or the combination, but not with nilotinib alone, significantly impaired their engraftment potential in NOD/SCID/IL2Rγ-null-3/GM/SF mice and significantly prolonged survival. Our data suggest potential benefit of concomitant β-catenin and Bcr-Abl inhibition to prevent or overcome Bcr-Abl kinase-dependent or -independent TKI resistance in BC-CML.

Combined inhibition of β-catenin and Bcr–Abl synergistically targets tyrosine kinase inhibitor-resistant blast crisis chronic myeloid leukemia blasts and progenitors in vitro and in vivo

PubMed Central

Zhou, H; Mak, P Y; Mu, H; Mak, D H; Zeng, Z; Cortes, J; Liu, Q; Andreeff, M; Carter, B Z

2017-01-01

Tyrosine kinase inhibitor (TKI) resistance and progression to blast crisis (BC), both related to persistent β-catenin activation, remain formidable challenges for chronic myeloid leukemia (CML). We observed overexpression of β-catenin in BC-CML stem/progenitor cells, particularly in granulocyte–macrophage progenitors, and highest among a novel CD34+CD38+CD123hiTim-3hi subset as determined by CyTOF analysis. Co-culture with mesenchymal stromal cells (MSCs) induced the expression of β-catenin and its target CD44 in CML cells. A novel Wnt/β-catenin signaling modulator, C82, and nilotinib synergistically killed KBM5T315I and TKI-resistant primary BC-CML cells with or without BCR–ABL kinase mutations even under leukemia/MSC co-culture conditions. Silencing of β-catenin by short interfering RNA restored sensitivity of primary BCR–ABLT315I/E255V BC-CML cells to nilotinib. Combining the C82 pro-drug, PRI-724, with nilotinib significantly prolonged the survival of NOD/SCID/IL2Rγ null mice injected with primary BCR–ABLT315I/E255V BC-CML cells. The combined treatment selectively targeted CML progenitors and inhibited CD44, c-Myc, survivin, p-CRKL and p-STAT5 expression. In addition, pretreating primary BC-CML cells with C82, or the combination, but not with nilotinib alone, significantly impaired their engraftment potential in NOD/SCID/IL2Rγ-null-3/GM/SF mice and significantly prolonged survival. Our data suggest potential benefit of concomitant β-catenin and Bcr–Abl inhibition to prevent or overcome Bcr–Abl kinase-dependent or -independent TKI resistance in BC-CML. PMID:28321124

Study on the shock interference in a wedged convergent-divergent channel

NASA Astrophysics Data System (ADS)

Yu, F. M.; Wang, C. Z.

The investigation of shock reflection-to-diffraction phenomena upon a wedged convergent-divergent channel produced by a planar incident shock wave have been done in the shock tube facility of Institute of Aeronautics and Astronautics, National Cheng-Kung University. The experiment proceeds upon seven wedged convergent-divergent channels with the forward and rear wedge angles arrangement of them are (50°, 50°), (35°, 35°), (50°, 35°), (35°, 50°), (50°, 0°), (35°, 0°), and (90°, 0°), respectively. They were tested at Mach numbers of 1.1, 1.2, 1.3, 1.4, 1.5 and 1.6, respectively. On the first wedged channel, following the regular reflection on a 50°- wedged surface by the incident shock wave, shock diffraction with Mach stem has been observed as it moves to the downstream wedge surface. On the apex of the wedge, the secondary reflected shock behaviors as a sector of the blast shock moving toward the centerline of the channel. From the color schlieren pictures it has been observed that there exists a pattern of blast-wave-type high gas density gradient region near the wedge apex. Following the Mach reflection from the 35° -wedged surface on which only the Mach stem diffracted across the apex and following with a small region of disturbed acoustic wave front. The shock interference, which proceeds by the Mach reflection-to-diffraction generates a very complicate vortical flow structure. The measurement of the peak pressure along centerline of the channel downstream of the wedge apex indicates that it is larger near the apex and it decreases downstream. It is larger for larger convergent wedge angle and It is smaller for larger divergent wedge angle.

Computing the stresses and deformations of the human eye components due to a high explosive detonation using fluid-structure interaction model.

PubMed

Karimi, Alireza; Razaghi, Reza; Navidbakhsh, Mahdi; Sera, Toshihiro; Kudo, Susumu

2016-05-01

In spite the fact that a very small human body surface area is comprised by the eye, its wounds due to detonation have recently been dramatically amplified. Although many efforts have been devoted to measure injury of the globe, there is still a lack of knowledge on the injury mechanism due to Primary Blast Wave (PBW). The goal of this study was to determine the stresses and deformations of the human eye components, including the cornea, aqueous, iris, ciliary body, lens, vitreous, retina, sclera, optic nerve, and muscles, attributed to PBW induced by trinitrotoluene (TNT) explosion via a Lagrangian-Eulerian computational coupling model. Magnetic Resonance Imaging (MRI) was employed to establish a Finite Element (FE) model of the human eye according to a normal human eye. The solid components of the eye were modelled as Lagrangian mesh, while an explosive TNT, air domain, and aqueous were modelled using Arbitrary Lagrangian-Eulerian (ALE) mesh. Nonlinear dynamic FE simulations were accomplished using the explicit FE code, namely LS-DYNA. In order to simulate the blast wave generation, propagation, and interaction with the eye, the ALE formulation with Jones-Wilkins-Lee (JWL) equation defining the explosive material were employed. The results revealed a peak stress of 135.70kPa brought about by detonation upsurge on the cornea at the distance of 25cm. The highest von Mises stresses were observed on the sclera (267.3kPa), whereas the lowest one was seen on the vitreous body (0.002kPa). The results also showed a relatively high resultant displacement for the macula as well as a high variation for the radius of curvature for the cornea and lens, which can result in both macular holes, optic nerve damage and, consequently, vision loss. These results may have implications not only for understanding the value of stresses and strains in the human eye components but also giving an outlook about the process of PBW triggers damage to the eye. Copyright © 2016 Elsevier Ltd. All rights reserved.

Considerations for animal models of blast-related traumatic brain injury and chronic traumatic encephalopathy.

PubMed

Goldstein, Lee E; McKee, Ann C; Stanton, Patric K

2014-01-01

The association of military blast exposure and brain injury was first appreciated in World War I as commotio cerebri, and later as shell shock. Similar injuries sustained in modern military conflicts are now classified as mild traumatic brain injury (TBI). Recent research has yielded new insights into the mechanisms by which blast exposure leads to acute brain injury and chronic sequelae, including postconcussive syndrome, post-traumatic stress disorder, post-traumatic headache, and chronic traumatic encephalopathy, a tau protein neurodegenerative disease. Impediments to delivery of effective medical care for individuals affected by blast-related TBI include: poor insight into the heterogeneity of neurological insults induced by blast exposure; limited understanding of the mechanisms by which blast exposure injures the brain and triggers sequelae; failure to appreciate interactive injuries that affect frontal lobe function, pituitary regulation, and neurovegetative homeostasis; unknown influence of genetic risk factors, prior trauma, and comorbidities; absence of validated diagnostic criteria and clinical nosology that differentiate clinical endophenotypes; and lack of empirical evidence to guide medical management and therapeutic intervention. While clinicopathological analysis can provide evidence of correlative association, experimental use of animal models remains the primary tool for establishing causal mechanisms of disease. However, the TBI field is confronted by a welter of animal models with varying clinical relevance, thereby impeding scientific coherence and hindering translational progress. Animal models of blast TBI will be far more translationally useful if experimental emphasis focuses on accurate reproduction of clinically relevant endpoints (output) rather than scaled replication of idealized blast shockwaves (input). The utility of an animal model is dependent on the degree to which the model recapitulates pathophysiological mechanisms, neuropathological features, and neurological sequelae observed in the corresponding human disorder. Understanding the purpose of an animal model and the criteria by which experimental results derived from the model are validated are critical components for useful animal modeling. Animal models that reliably demonstrate clinically relevant endpoints will expedite development of new treatments, diagnostics, preventive measures, and rehabilitative strategies for individuals affected by blast TBI and its aftermath.

Considerations for animal models of blast-related traumatic brain injury and chronic traumatic encephalopathy

PubMed Central

2014-01-01

The association of military blast exposure and brain injury was first appreciated in World War I as commotio cerebri, and later as shell shock. Similar injuries sustained in modern military conflicts are now classified as mild traumatic brain injury (TBI). Recent research has yielded new insights into the mechanisms by which blast exposure leads to acute brain injury and chronic sequelae, including postconcussive syndrome, post-traumatic stress disorder, post-traumatic headache, and chronic traumatic encephalopathy, a tau protein neurodegenerative disease. Impediments to delivery of effective medical care for individuals affected by blast-related TBI include: poor insight into the heterogeneity of neurological insults induced by blast exposure; limited understanding of the mechanisms by which blast exposure injures the brain and triggers sequelae; failure to appreciate interactive injuries that affect frontal lobe function, pituitary regulation, and neurovegetative homeostasis; unknown influence of genetic risk factors, prior trauma, and comorbidities; absence of validated diagnostic criteria and clinical nosology that differentiate clinical endophenotypes; and lack of empirical evidence to guide medical management and therapeutic intervention. While clinicopathological analysis can provide evidence of correlative association, experimental use of animal models remains the primary tool for establishing causal mechanisms of disease. However, the TBI field is confronted by a welter of animal models with varying clinical relevance, thereby impeding scientific coherence and hindering translational progress. Animal models of blast TBI will be far more translationally useful if experimental emphasis focuses on accurate reproduction of clinically relevant endpoints (output) rather than scaled replication of idealized blast shockwaves (input). The utility of an animal model is dependent on the degree to which the model recapitulates pathophysiological mechanisms, neuropathological features, and neurological sequelae observed in the corresponding human disorder. Understanding the purpose of an animal model and the criteria by which experimental results derived from the model are validated are critical components for useful animal modeling. Animal models that reliably demonstrate clinically relevant endpoints will expedite development of new treatments, diagnostics, preventive measures, and rehabilitative strategies for individuals affected by blast TBI and its aftermath. PMID:25478023

Study on the early warning mechanism for the security of blast furnace hearths

NASA Astrophysics Data System (ADS)

Zhao, Hong-bo; Huo, Shou-feng; Cheng, Shu-sen

2013-04-01

The campaign life of blast furnace (BF) hearths has become the limiting factor for safety and high efficiency production of modern BFs. However, the early warning mechanism of hearth security has not been clear. In this article, based on heat transfer calculations, heat flux and erosion monitoring, the features of heat flux and erosion were analyzed and compared among different types of hearths. The primary detecting elements, mathematical models, evaluating standards, and warning methods were discussed. A novel early warning mechanism with the three-level quantificational standards was proposed for BF hearth security.

Kaon femtoscopy in Au+Au collisions at √SNN = 200 GeV at the STAR experiment

NASA Astrophysics Data System (ADS)

Lidrych, Jindřich

2018-02-01

In this proceedings, the STAR preliminary results on femtoscopic correlations of identical kaons from Au+Au collisions at =200 GeV are presented. The measured kaon source radii are studied as a function of collision energy as well as centrality and transverse pair mass mT. In addition, extracted kaon blast-wave freeze-out parameters are presented.

Blast Induced Liquefaction Potential and Transient Porewater Pressure Response of Saturated Sands.

DTIC Science & Technology

1985-10-15

14 2. CartquresIbducityGroundNotion.................... ... 16 .omaio fLefaction Mechsmse................ 17 . Pl...soil-water system by a factor of 16 , and reduce the wave propagation velocity by a factor of four. While liquefaction of materials containing air bubbles...restore the 16 effective stress. Low permeability soils, such as fine silts and low sensitivity clays, are not usually prone to liquefaction. Coarse silts

Time Evolution of the Density Field of a Micro-Explosion Using Background Oriented Schlieren

NASA Astrophysics Data System (ADS)

Suriyanarayanan, P.; Venkatakrishnan, L.; Jagadeesh, G.

In recent years micro-explosions have found interesting trans-disciplinary applications in the areas of food preservation,wood science, drug delivery, gene therapy and bio-medical applications [1, 2]. Generating controlled micro-explosions in a laboratory environment in a reliable manner is essential; to study and understand some of the near field flow dynamics associated with blast waves.

DRoplet and hAdron generator for nuclear collisions: An update

NASA Astrophysics Data System (ADS)

Tomášik, Boris

2016-10-01

The Monte Carlo generator DRAGON simulates hadron production in ultrarelativistic nuclear collisions. The underlying theoretical description is provided by the blast-wave model. DRAGON includes second-order angular anisotropy in transverse shape and the amplitude of the transverse expansion velocity. It also allows to simulate hadron production from a fragmented fireball, e.g. as resulting from spinodal decomposition happening at the first-order phase transition.

Interaction of Bio-Aerosols with Shock/Blast Waves: Dispersion, Activation, and Destruction of Airborne Biological Threats

DTIC Science & Technology

2011-05-01

laboratory protocol was used to investigate the post-shock-heating survival of three strains of endospores ( Bacillus atrophaeus, Bacillus subtilis ...investigate the post-shock-heating survival of three strains of endospores ( Bacillus atrophaeus, Bacillus subtilis and Bacillus thuringiensis, Al Hakam...investigated: Bacillus subtilis , Bacillus atrophaeus and Bacillus thuringiensis (Al Hakam). The exposporium on these three strains are radically different

Dynamic Pressure Impulse for Near-Ideal and Non-Ideal Blast Waves -- Height of Burst Charts

DTIC Science & Technology

1981-05-15

identI by block numiber) FIELD JGROUP ISUIS4NOUP Nucler Weapons Effects Dynamic Pressure Impulse IB 1 3 1Airblast (Nuclear) Height of Burst 1 1 4...impulse versus displacement and vice versa. The power func- tions were used to separately fit the data for the WWII and the M38A1 1/4 ton trucks

Observation and modeling of mixing-layer development in HED blast-wave-driven shear flow

NASA Astrophysics Data System (ADS)

di Stefano, Carlos

2013-10-01

This talk describes work exploring the sensitivity to initial conditions of hydrodynamic mixing-layer growth due to shear flow in the high-energy-density regime. This work features an approach in two parts, experimental and theoretical. First, an experiment, conducted at the OMEGA-60 laser facility, seeks to measure the development of such a mixing layer. This is accomplished by placing a layer of low-density (initially of either 0.05 or 0.1 g/cm3, to vary the system's Atwood number) carbon foam against a layer of higher-density (initially 1.4 g/cm3) polyamide-imide that has been machined to a nominally-flat surface at its interface with the foam. Inherent roughness of this surface's finish is precisely measured and varied from piece to piece. Ten simultaneous OMEGA beams, comprising a 4.5 kJ, 1-ns pulse focused to a roughly 1-mm-diameter spot, irradiate a thin polycarbonate ablator, driving a blast wave into the foam, parallel to its interface with the polyamide-imide. The ablator is framed by a gold washer, such that the blast wave is driven only into the foam, and not into the polyamide-imide. The subsequent forward motion of the shocked foam creates the desired shear effect, and the system is imaged by X-ray radiography 35 ns after the beginning of the driving laser pulse. Second, a simulation is performed, intending to replicate the flow observed in the experiment as closely as possible. Using the resulting simulated flow parameters, an analytical model can be used to predict the evolution of the mixing layer, as well as track the motion of the fluid in the experiment prior to the snapshot seen in the radiograph. The ability of the model to predict growth of the mixing layer under the various conditions observed in the experiment is then examined. This work is funded by the Predictive Sciences Academic Alliances Program in NNSA-ASC via grant DEFC52- 08NA28616, by the NNSA-DS and SC-OFES Joint Program in High-Energy-Density Laboratory Plasmas, grant number DE-NA0001840, and by the National Laser Use.

Disaster preparedness, pediatric considerations in primary blast injury, chemical, and biological terrorism

PubMed Central

Hamele, Mitchell; Poss, William Bradley; Sweney, Jill

2014-01-01

Both domestic and foreign terror incidents are an unfortunate outgrowth of our modern times from the Oklahoma City bombings, Sarin gas attacks in Japan, the Madrid train bombing, anthrax spores in the mail, to the World Trade Center on September 11th, 2001. The modalities used to perpetrate these terrorist acts range from conventional weapons to high explosives, chemical weapons, and biological weapons all of which have been used in the recent past. While these weapons platforms can cause significant injury requiring critical care the mechanism of injury, pathophysiology and treatment of these injuries are unfamiliar to many critical care providers. Additionally the pediatric population is particularly vulnerable to these types of attacks. In the event of a mass casualty incident both adult and pediatric critical care practitioners will likely be called upon to care for children and adults alike. We will review the presentation, pathophysiology, and treatment of victims of blast injury, chemical weapons, and biological weapons. The focus will be on those injuries not commonly encountered in critical care practice, primary blast injuries, category A pathogens likely to be used in terrorist incidents, and chemical weapons including nerve agents, vesicants, pulmonary agents, cyanide, and riot control agents with special attention paid to pediatric specific considerations. PMID:24834398

The Balloon-borne Large Aperture Submillimeter Telescope: BLAST

NASA Astrophysics Data System (ADS)

Truch, Matthew D. P.; Ade, P. A. R.; Bock, J. J.; Chapin, E. L.; Chung, J.; Devlin, M. J.; Dicker, S.; Griffin, M.; Gundersen, J. O.; Halpern, M.; Hargrave, P. C.; Hughes, D. H.; Klein, J.; MacTavish, C. J.; Marsden, G.; Martin, P. G.; Martin, T. G.; Mauskopf, P.; Netterfield, C. B.; Olmi, L.; Pascale, E.; Patanchon, G.; Rex, M.; Scott, D.; Semisch, C.; Thomas, N. E.; Tucker, C.; Tucker, G. S.; Viero, M. P.; Wiebe, D. V.

2009-01-01

The Balloon-borne Large Aperture Submillimeter Telescope (BLAST) is a suborbital surveying experiment designed to study the evolutionary history and processes of star formation in local galaxies (including the Milky Way) and galaxies at cosmological distances. The BLAST continuum camera, which consists of 270 detectors distributed between three arrays, observes simultaneously in broadband (30%) spectral windows at 250, 350, and 500 microns. The optical design is based on a 2 m diameter telescope, providing a diffraction-limited resolution of 30" at 250 microns. The gondola pointing system enables raster mapping of arbitrary geometry, with a repeatable positional accuracy of 30"; postflight pointing reconstruction to <5" rms is achieved. The onboard telescope control software permits autonomous execution of a preselected set of maps, with the option of manual override. On this poster, we describe the primary characteristics and measured in-flight performance of BLAST. BLAST performed a test flight in 2003 and has since made two scientifically productive long-duration balloon flights: a 100 hour flight from ESRANGE (Kiruna), Sweden to Victoria Island, northern Canada in 2005 June; and a 250 hour, circumpolar flight from McMurdo Station, Antarctica in 2006 December. The BLAST collaboration acknowledges the support of NASA through grants NAG5-12785, NAG5-13301, and NNGO-6GI11G, the Canadian Space Agency (CSA), the Science and Technology Facilities Council (STFC), Canada's Natural Sciences and Engineering Research Council (NSERC), the Canada Foundation for Innovation, the Ontario Innovation Trust, the Puerto Rico Space Grant Consortium, the Fondo Institucional para la Investigacion of the University of Puerto Rico, and the National Science Foundation Office of Polar Programs.

Propulsion system ignition overpressure for the Space Shuttle

NASA Technical Reports Server (NTRS)

Ryan, R. S.; Jones, J. H.; Guest, S. H.; Struck, H. G.; Rheinfurth, M. H.; Verferaime, V. S.

1981-01-01

Liquid and solid rocket motor propulsion systems create an overpressure wave during ignition, caused by the accelerating gas particles pushing against or displacing the air contained in the launch pad or launch facility and by the afterburning of the fuel-rich gases. This wave behaves as a blast or shock wave characterized by a positive triangular-shaped first pulse and a negative half-sine wave second pulse. The pulse travels up the space vehicle and has the potential of either overloading individual elements or exciting overall vehicle dynamics. The latter effect results from the phasing difference of the wave from one side of the vehicle to the other. This overpressure phasing, or delta P environment, because of its frequency content as well as amplitude, becomes a design driver for certain panels (e.g., thermal shields) and payloads for the Space Shuttle. The history of overpressure effects on the Space Shuttle, the basic overpressure phenomenon, Space Shuttle overpressure environment, scale model overpressure testing, and techniques for suppressing the overpressure environments are considered.

A study of phase explosion of metal using high power Nd:YAG laser ablation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yoh, Jack J.; Lee, H. H.; Choi, J. H.

2007-12-12

The interaction of high-power pulsed-laser beam with metal targets in air from 1.06 {mu}m, 5 ns, 3 J/pulse max, Nd:YAG pulsed laser is investigated together with hydrodynamic theories of laser-supported detonation (LSD) wave and multi-material reactive Euler equations. The high speed blast wave generated by the laser ablation of metal reaches maximum velocity of several thousand meters per second. The apparently similar flow conditions to those of reactive shock wave allow one to apply the equations of motion for energetic materials and to understand the explosive behavior of metal vaporization upon laser ablation. The characteristic time at which planar tomore » spherical wave transition occurs is confirmed at low (20 mJ/pulse) to higher (200 mJ/pulse) beam intensities. The flow structure behind the leading shock wave during the early planar shock state is confirmed by the high-resolution multi-material hydrocode originally developed for shock compression of condensed matter.« less

Reactions in the Tuyere Zone of Ironmaking Blast Furnace

NASA Astrophysics Data System (ADS)

Ma, Xiaodong; Zhu, Jinming; Xu, Haifa; Wang, Geoff; Lee, Hae-Geon; Zhao, Baojun

2018-02-01

A series of slags can be formed in the lower part of the ironmaking blast furnace that play important roles in smooth furnace operation, and in determining iron quality and productivity. The final slag tapped from the BF has been investigated extensively as it can be collected directly. Unfortunately, difficulties in accessing the interiors of the blast furnace limit the full understanding of other slags such as primary and bosh slags. In this study, different types of samples directly obtained from the tuyere zone of the blast furnace have been systematically analyzed and characterized using scanning electron microscopy (SEM), electron probe X-ray microanalysis (EPMA), and X-ray fluorescence (XRF), with focus on the characteristics of slags formed in the tuyere level. The samples were identified into three groups according to their morphological, mineralogical, and chemical properties: (1) tuyere slags originating from the reactions between ash and dripping slags; (2) bosh slags in the CaO-SiO2-Al2O3-MgO-FeO system, with a CaO/SiO2 weight ratio of around 1.50, and Al2O3 and MgO concentrations close to those of final slags; and (3) coke ash that did not react with bosh slags. These findings will provide useful information on the evaluation of slags inside the blast furnace and the reactions in the tuyere zone.

Rapid evolution of avirulence genes in rice blast fungus Magnaporthe oryzae

PubMed Central

2014-01-01

Background Rice blast fungus Magnaporthe oryzae is one of the most devastating pathogens in rice. Avirulence genes in this fungus share a gene-for-gene relationship with the resistance genes in its host rice. Although numerous studies have shown that rice blast R-genes are extremely diverse and evolve rapidly in their host populations, little is known about the evolutionary patterns of the Avr-genes in the pathogens. Results Here, six well-characterized Avr-genes and seven randomly selected non-Avr control genes were used to investigate the genetic variations in 62 rice blast strains from different parts of China. Frequent presence/absence polymorphisms, high levels of nucleotide variation (~10-fold higher than non-Avr genes), high non-synonymous to synonymous substitution ratios, and frequent shared non-synonymous substitution were observed in the Avr-genes of these diversified blast strains. In addition, most Avr-genes are closely associated with diverse repeated sequences, which may partially explain the frequent presence/absence polymorphisms in Avr-genes. Conclusion The frequent deletion and gain of Avr-genes and rapid non-synonymous variations might be the primary mechanisms underlying rapid adaptive evolution of pathogens toward virulence to their host plants, and these features can be used as the indicators for identifying additional Avr-genes. The high number of nucleotide polymorphisms among Avr-gene alleles could also be used to distinguish genetic groups among different strains. PMID:24725999

Blast Overpressure Studies with Animals and Man: Biological Response to Complex Blast Waves

DTIC Science & Technology

1993-10-31

cases, hemorrhage and edema reduced the lumen diameter of the organ making it difficult to breath. In subjects with extensive lung hemorrhage, confluent...IAF ui UU LU WiL N .4 C A p ... 4 n 1 - u- --- -j -j -j*-1 LA ZN MA’ P W I 4A MC I A U A( A fac U a*gJ*J~ U09 "~L rn in CM ININ~~ :2-. :2 a) - 41...tuU UU j ** ~ ~ ~ ( (A 0O~ -t u’ CO (Ao -*~~~L us~N-sr, ULA -U z, zd z~ 2*- . .01 -0 c Xo cm 1:2 𔃺 CO 2 L^m C .- Mp i m 3 - K -1§ LA x ’U.’x 0’ x Ixx

Temperature relaxation in supernova remnants, revisited

NASA Technical Reports Server (NTRS)

Itoh, H.

1984-01-01

Some supernova remnants are expanding into a partially neutral medium. The neutral atoms which are engulfed by the fast blast shock are collisionally ionized to eject low-energy secondary electrons. Calculations are conducted of the temperature relaxation through Coulomb collisions among the secondary electrons, the shocked electrons, and the ions, assuming that the three species have Maxwellian velocity distributions. The results are applied to a self-similar blast wave. If the efficiency of collisionless electron heating at the shock front is high in young remnants such as Tycho, the secondary electrons may be much cooler than both the shocked electrons and the ions. In this case, the emergent X-ray continuum spectrum will have a two-temperature, or a power-law, appearance. This effect may have been observed in the bright rim of the remnant of SN 1006.

Analysis of Fuel Injection and Atomization of a Hybrid Air-Blast Atomizer.

NASA Astrophysics Data System (ADS)

Ma, Peter; Esclape, Lucas; Buschhagen, Timo; Naik, Sameer; Gore, Jay; Lucht, Robert; Ihme, Matthias

2015-11-01

Fuel injection and atomization are of direct importance to the design of injector systems in aviation gas turbine engines. Primary and secondary breakup processes have significant influence on the drop-size distribution, fuel deposition, and flame stabilization, thereby directly affecting fuel conversion, combustion stability, and emission formation. The lack of predictive modeling capabilities for the reliable characterization of primary and secondary breakup mechanisms is still one of the main issues in improving injector systems. In this study, an unstructured Volume-of-Fluid method was used in conjunction with a Lagrangian-spray framework to conduct high-fidelity simulations of the breakup and atomization processes in a realistic gas turbine hybrid air blast atomizer. Results for injection with JP-8 aviation fuel are presented and compared to available experimental data. Financial support through the FAA National Jet Fuel Combustion Program is gratefully acknowledged.

CFD Applications in Support of the Space Shuttle Risk Assessment

NASA Technical Reports Server (NTRS)

Baum, Joseph D.; Mestreau, Eric; Luo, Hong; Sharov, Dmitri; Fragola, Joseph; Loehner, Rainald; Cook, Steve (Technical Monitor)

2000-01-01

The paper describes a numerical study of a potential accident scenario of the space shuttle, operating at the same flight conditions as flight 51L, the Challenger accident. The interest in performing this simulation is derived by evidence that indicates that the event itself did not exert large enough blast loading on the shuttle to break it apart. Rather, the quasi-steady aerodynamic loading on the damaged, unbalance vehicle caused the break-up. Despite the enormous explosive potential of the shuttle total fuel load (both liquid and solid), the post accident explosives working group estimated the maximum energy involvement to be equivalent to about five hundreds of pounds of TNT. This understanding motivated the simulation described here. To err on the conservative side, we modeled the event as an explosion, and used the maximum energy estimate. We modeled the transient detonation of a 500 lbs spherical charge of TNT, placed at the main engine, and the resulting blast wave propagation about the complete stack. Tracking of peak pressures and impulses at hundreds of locations on the vehicle surface indicate that the blast load was insufficient to break the vehicle, hence demonstrating likely crew survivability through such an event.

The spatial distribution patterns of condensed phase post-blast explosive residues formed during detonation.

PubMed

Abdul-Karim, Nadia; Blackman, Christopher S; Gill, Philip P; Karu, Kersti

2016-10-05

The continued usage of explosive devices, as well as the ever growing threat of 'dirty' bombs necessitates a comprehensive understanding of particle dispersal during detonation events in order to develop effectual methods for targeting explosive and/or additive remediation efforts. Herein, the distribution of explosive analytes from controlled detonations of aluminised ammonium nitrate and an RDX-based explosive composition were established by systematically sampling sites positioned around each firing. This is the first experimental study to produce evidence that the post-blast residue mass can distribute according to an approximate inverse-square law model, while also demonstrating for the first time that distribution trends can vary depending on individual analytes. Furthermore, by incorporating blast-wave overpressure measurements, high-speed imaging for fireball volume recordings, and monitoring of environmental conditions, it was determined that the principle factor affecting all analyte dispersals was the wind direction, with other factors affecting specific analytes to varying degrees. The dispersal mechanism for explosive residue is primarily the smoke cloud, a finding which in itself has wider impacts on the environment and fundamental detonation theory. Copyright © 2016 The Authors. Published by Elsevier B.V. All rights reserved.

Use of high-speed visualization for the study of shock-wave interactions with deformable porous materials

NASA Astrophysics Data System (ADS)

Skews, Beric W.; Glick, Gavin; Doyle, Graham K.; Lamond, Paul W.

1997-05-01

This paper describes the use of high-speed photography, and videography, in the study of material distortion and movement when a shock wave traverses a highly deformable porous structure, such as a blob of foam or a porous bed of particles. The effects of surface porosity can be significant in determining the nature of reflection of shock waves from surfaces. Not only are wave geometries substantially modified but the resulting wall pressures are also strongly affected. It, in addition, the surface is highly deformable by being made up of an elastic matrix or a collection of discrete particles, then the reflection geometry and loading can be even more complex. It is known, for example, that shock wave impact on open-cell polyurethane foam attached to a wall can cause a significant increase in pressure on the wall compared to reflection off a plane rigid wall without covering. The motion of the interface is an essential consideration in understanding the dynamics of these interactions. These studies could have application to the effects of blast wave propagation over complex surfaces such as forests, grasslands, and snow; as well as in establishing the efficacy of safety padding and attenuation materials under shock and impact loading conditions. Studies on an assortment of materials are presented, using a variety of visualization techniques. Recording methods used range from short duration flash photography (both shadow and schlieren), through multi-frame videography; to single frame, multi-exposure video capture with a camera capable of rates up to 1 million pictures per second. In the case of shock wave impact on specimens of polyurethane foam, the results clearly show the expulsion and reingestion of shock heated gas from within the foam body as the material collapses and then recovers, coupled with longitudinal and transverse oscillations of the body of the foam material. For blast wave propagation over porous beds, occurrence of particle lift off, bed fluidization, and the generation of surface dunes are evident. The recordings allow the calculation of the velocities and accelerations of the various interfaces and particles to be made, using suitable image processing techniques. Thus, estimates may be made of the unsteady drag forces acting on the individual particles.

Modelling blast induced damage from a fully coupled explosive charge

PubMed Central

Onederra, Italo A.; Furtney, Jason K.; Sellers, Ewan; Iverson, Stephen

2015-01-01

This paper presents one of the latest developments in the blasting engineering modelling field—the Hybrid Stress Blasting Model (HSBM). HSBM includes a rock breakage engine to model detonation, wave propagation, rock fragmentation, and muck pile formation. Results from two controlled blasting experiments were used to evaluate the code’s ability to predict the extent of damage. Results indicate that the code is capable of adequately predicting both the extent and shape of the damage zone associated with the influence of point-of-initiation and free-face boundary conditions. Radial fractures extending towards a free face are apparent in the modelling output and matched those mapped after the experiment. In the stage 2 validation experiment, the maximum extent of visible damage was of the order of 1.45 m for the fully coupled 38-mm emulsion charge. Peak radial velocities were predicted within a relative difference of only 1.59% at the nearest history point at 0.3 m from the explosive charge. Discrepancies were larger further away from the charge, with relative differences of −22.4% and −42.9% at distances of 0.46 m and 0.61 m, respectively, meaning that the model overestimated particle velocities at these distances. This attenuation deficiency in the modelling produced an overestimation of the damage zone at the corner of the block due to excessive stress reflections. The extent of visible damage in the immediate vicinity of the blasthole adequately matched the measurements. PMID:26412978

Design and Implementation of an Underwater Sound Recording Device

PubMed Central

Martinez, Jayson J.; Myers, Josh R.; Carlson, Thomas J.; Deng, Z. Daniel; Rohrer, John S.; Caviggia, Kurt A.; Woodley, Christa M.; Weiland, Mark A.

2011-01-01

To monitor the underwater sound and pressure waves generated by anthropogenic activities such as underwater blasting and pile driving, an autonomous system was designed to record underwater acoustic signals. The underwater sound recording device (USR) allows for connections of two hydrophones or other dynamic pressure sensors, filters high frequency noise out of the collected signals, has a gain that can be independently set for each sensor, and allows for 2 h of data collection. Two versions of the USR were created: a submersible model deployable to a maximum depth of 300 m, and a watertight but not fully submersible model. Tests were performed on the USR in the laboratory using a data acquisition system to send single-frequency sinusoidal voltages directly to each component. These tests verified that the device operates as designed and performs as well as larger commercially available data acquisition systems, which are not suited for field use. On average, the designed gain values differed from the actual measured gain values by about 0.35 dB. A prototype of the device was used in a case study to measure blast pressures while investigating the effect of underwater rock blasting on juvenile Chinook salmon and rainbow trout. In the case study, maximum positive pressure from the blast was found to be significantly correlated with frequency of injury for individual fish. The case study also demonstrated that the device withstood operation in harsh environments, making it a valuable tool for collecting field measurements. PMID:22164089

Frequency and Reasons for Return to Acute Care in Leukemia Patients Undergoing Inpatient Rehabilitation

PubMed Central

Fu, Jack Brian; Lee, Jay; Smith, Dennis W.; Bruera, Eduardo

2012-01-01

Objective To assess the frequency and reasons for return to the primary acute care service among leukemia patients undergoing inpatient rehabilitation. Design Retrospective study of all patients with leukemia, myelodysplastic syndrome, aplastic anemia, or myelofibrosis admitted to inpatient rehabilitation at a tertiary referral-based cancer center between January 1, 2005, and April 10, 2012. Items analyzed from patient records included return to the primary acute care service with demographic information, leukemia characteristics, medications, hospital admission characteristics, and laboratory values. Results 225 patients were admitted a total of 255 times. 93/255 (37%) of leukemia inpatient rehabilitation admissions returned to the primary acute care service. 18/93 (19%) and 42/93 (45%) of these patients died in the hospital and were discharged home respectively. Statistically significant factors (p<.05) associated with return to the primary acute care service include peripheral blast percentage and the presence of an antifungal agent on the day of inpatient rehabilitation transfer. Using an additional two factors (platelet count and the presence of an antiviral agent both with a p<.11), a Return To Primary (RTP) - Leukemia index was formulated. Conclusions Leukemia patients with the presence of circulating peripheral blasts and/or antifungal agent may be at increased risk of return to the primary acute care service. The RTP-Leukemia index should be tested in prospective studies to determine its usefulness. PMID:23117267

Imaging of Combat-Related Thoracic Trauma - Blunt Trauma and Blast Lung Injury.

PubMed

Lichtenberger, John P; Kim, Andrew M; Fisher, Dane; Tatum, Peter S; Neubauer, Brian; Peterson, P Gabriel; Carter, Brett W

2018-03-01

Combat-related thoracic trauma (CRTT) is a significant contributor to morbidity and mortality of the casualties from Operation Enduring Freedom (OEF) and Operation Iraqi Freedom (OIF). Penetrating, blunt, and blast injuries are the most common mechanisms of trauma to the chest. Imaging plays a key role in the battlefield management of CRTT casualties. This work discusses the imaging manifestations of thoracic injuries from blunt trauma and blast injury, emphasizing epidemiology and diagnostic clues seen during OEF and OIF. The assessment of radiologic findings in patients who suffer from combat-related blunt thoracic trauma and blast injury is the basis of this work. The imaging modalities for this work include multi-detector computed tomography (MDCT) and chest radiography. Multiple imaging modalities are available to imagers on or near the battlefront, including radiography, fluoroscopy, and MDCT. MDCT with multi-planar reconstructions is the most sensitive imaging modality available in combat hospitals for the evaluation of CRTT. In modern combat, blunt and blast injuries account for a significant portion of CRTT. Individual body armor converts penetrating trauma to blunt trauma, leading to pulmonary contusion that accounted for 50.2% of thoracic injuries during OIF and OEF. Flail chest, a subset of blunt chest injury, is caused by significant blunt force to the chest and occurs four times as frequently in combat casualties when compared with the civilian population. Imaging features of CRTT have significant diagnostic and prognostic value. Pulmonary contusions on chest radiography appear as patchy consolidations in the acute setting with ill-defined and non-segmental borders. MDCT of the chest is a superior imaging modality in diagnosing and evaluating pulmonary contusion. Contusions on MDCT appear as crescentic ground-glass opacities (opacities through which lung interstitium and vasculature are still visible) and areas of consolidation that often do not respect the anatomic boundaries of the affected lobes. Additionally, small pulmonary contusions may exhibit sub-pleural sparing and may distinguish contusion from pneumonia or other lung pathology. Although pulmonary laceration is typically the result of penetrating trauma, laceration may also be caused by displaced rib fractures or significant shearing forces on the lung without penetrating injury. Because of elastic recoil of the normal pulmonary parenchyma surrounding the injury, pulmonary lacerations may present as late as 48-72 h after injury. Pulmonary lacerations may appear similar to pulmonary contusions on chest radiography initially and will require MDCT for definitive diagnosis. Blast injury is a defining injury of modern combat. Blast lung injury is initially diagnosed with chest radiography, where the pattern of lung opacities has previously been described by clinicians as "batwing" or "butterfly" because of its central appearance in the lung. "Peribronchovascular" may be a more accurate description of primary blast lung based on its appearance on MDCT. This pattern may differentiate primary blast lung injury from other causes of thoracic trauma. CRTT continues to be a significant contributor to the morbidity and mortality of those injured during OEF and OIF. The distinct injury patterns and atypical imaging manifestations of blunt trauma and blast lung injury are important to recognize early because of the acuity of this patient population and the influence of accurate diagnosis on clinical management.

Development of unidentified dna-specific hif 1α gene of lizard (hemidactylus platyurus) which plays a role in tissue regeneration process

NASA Astrophysics Data System (ADS)

Novianti, T.; Sadikin, M.; Widia, S.; Juniantito, V.; Arida, E. A.

2018-03-01

Development of unidentified specific gene is essential to analyze the availability these genes in biological process. Identification unidentified specific DNA of HIF 1α genes is important to analyze their contribution in tissue regeneration process in lizard tail (Hemidactylus platyurus). Bioinformatics and PCR techniques are relatively an easier method to identify an unidentified gene. The most widely used method is BLAST (Basic Local Alignment Sequence Tools) method for alignment the sequences from the other organism. BLAST technique is online software from website https://blast.ncbi.nlm.nih.gov/Blast.cgi that capable to generate the similar sequences from closest kinship to distant kindship. Gecko japonicus is a species that it has closest kinship with H. platyurus. Comparing HIF 1 α gene sequence of G. japonicus with the other species used multiple alignment methods from Mega7 software. Conserved base areas were identified using Clustal IX method. Primary DNA of HIF 1 α gene was design by Primer3 software. HIF 1α gene of lizard (H. platyurus) was successfully amplified using a real-time PCR machine by primary DNA that we had designed from Gecko japonicus. Identification unidentified gene of HIF 1a lizard has been done successfully with multiple alignment method. The study was conducted by analyzing during the growth of tail on day 1, 3, 5, 7, 10, 13 and 17 of lizard tail after autotomy. Process amplification of HIF 1α gene was described by CT value in real time PCR machine. HIF 1α expression of gene is quantified by Livak formula. Chi-square statistic test is 0.000 which means that there is a different expression of HIF 1 α gene in every growth day treatment.

Detonation suppression in hydrogen-air mixtures using porous coatings on the walls

NASA Astrophysics Data System (ADS)

Bivol, G. Yu.; Golovastov, S. V.; Golub, V. V.

2018-05-01

We considered the problem of detonation suppression and weakening of blast wave effects occurring during the combustion of hydrogen-air mixtures in confined spaces. The gasdynamic processes during combustion of hydrogen, an alternative environmentally friendly fuel, were also considered. Detonation decay and flame propagation in hydrogen-air mixtures were experimentally investigated in rectangular cross-section channels with solid walls and two types of porous coatings: steel wool and polyurethane foam. Shock wave pressure dynamics inside the section with porous coating were studied using pressure sensors; flame front propagation was studied using photodiodes and high-speed camera visualization. For all mixtures, the detonation wave formed before entering the section with porous coating. For both porous materials, the steady detonation wave decoupled in the porous section of the channel into a shock wave and flame front propagating with a velocity around the Chapman-Jouguet acoustic velocity. By the end of the porous section, shock wave pressure reductions of 70 and 85% were achieved for the polyurethane foam and steel wool, respectively. The dependence of the flame velocity on the mixture composition (equivalence ratio) is presented.

Numerical Simulation of Blast Action on Civil Structures in Urban Environment

NASA Astrophysics Data System (ADS)

Valger, Svetlana A.; Fedorova, Natalya N.; Fedorov, Alexander V.

2017-10-01

Nowadays, a lot of industrial accidents accompanied by explosions are happening throughout the world. Also, increase in the number of terrorist acts committed by means of explosions is observed. For improving safety of buildings and structures it is necessary to raise their resistance to explosive effects, as well as to be able to predict degree of potential damage upon explosive loads of various intensities. One of the principal goals in designing the structure resistant to explosive effects is to determine the dynamic response of structures to the impact of the blast wave. To this end, the transient pressure loads on the walls of the civil engineering structures are to be determined. The simulation of explosion is highly complicated, involving an explosion causing the shock wave propagation in air and then interaction with a structure. The engineering-level techniques permit one to estimate an explosive shock impact only for isolated buildings. The complexity of the building, the presence of nearby structures and the surrounding environment cannot be taken into account. Advanced computer aid engineering (CAE) software techniques combined with the latest methods of discrete three-dimensional city modelling permits one to simulate and analyse the effects of explosions in urban areas with a precision which previously was not possible. In the paper, the simulation results are presented of shock wave forming due to a spherical explosive charge and its propagation in the vicinity of geometrical configuration imitating an urban environment. The numerical simulation of a flow in the vicinity of prisms of different cross-sections and heights located on a flat plate was performed. The calculations are carried out in a three-dimensional non-viscous formulation using ANSYS software. On a basis of simulation results, a complex wave structures were analysed, and all the peculiarities of flows and pressure history records on building walls were described and explained. The possibility of a correct description of the non-stationary wave flow in the vicinity of the complex of obstacles is demonstrated. The results are compared with the experimental data on the pressure distribution in gauges located on the prism walls. The estimation of shock wave exposure intensity was performed to different objects.

Numerical Investigation of Aluminum Burning Behind Blast Waves

DTIC Science & Technology

2010-10-01

Lai, and K.S. Im, “ Afterburning of TNT Explosive Products in Air with Aluminum Particles,” AIAA-2008-1029, 2008 [2] K. Balakrishnan and S. Menon...phase flow was applied. The modeled HE includes a significant percentage of aluminum particles, whose long-time afterburning and energy release must...the physical mechanisms are even more complex. The flow environment is significantly different from bare charge detonation and afterburn . As long

Blackjack

DTIC Science & Technology

2012-05-01

astar (C++) path finding algorithms.  bwaves (Fortran) simulation of blast waves in 3D transonic transient laminar viscous flow.  bzip2 (C) in...search based on Profile Hidden Markov Models.  lbm (C) implementation of Lattice Boltzman Method for simulation of incompressible fluids in 3D...to comply with a collection of information if it does not display a currently valid OMB control number. PLEASE DO NOT RETURN YOUR FORM TO THE ABOVE

Regional Surface Waves from Mesabi Range Mine Blasts (Northern Minnesota)

DTIC Science & Technology

1991-10-29

rocks within the Archean basement which underlies the Animikie basin near the source areas. The final analysis was two dimensional raytracing which...overlying the Archean basement. Overlying the Pokegama Quartzite is the Biwabik Iron Formation and the Virginia Formation (Morey, 1983, Southwick and others...composed of intercalated mudstone and siltstone turbidite deposits which thicken and coarsen progressively from north to south across the basin (Morey and

Chemical, Biological, Radiological, Nuclear, and High-Yield Explosives Consequences Management

DTIC Science & Technology

2006-10-02

cause three types of injuries: blast, thermal and radiation, as well as electromagnetic pulse (EMP) effects described further in a later section. (1...occur with conventional explosives and are further described in the next section. (2) Thermal injuries present as flash burns (burns from direct...exposure to the thermal radiation pulse, typically ultraviolet, visible, and infrared waves) or flame burns (burns from materials set afire by the infrared

Viscous Effects on Blast Wave Flowfields.

DTIC Science & Technology

1984-12-01

18 3-7 Grids used in shock-cylinder interaction calculations ....... ...................... ... 21 3-8 Pressure-time histories ...structure flow ........ .. 32 iv LIST OF ILLUSTRATIONS (concluded) r ~ue Pa e 4-2 Calculated pressure-time histories for shock-field structure...written in dimensionless, conservative-law formll ,r e orf t jas without external forces as follows: : *1 t, ’ yF 1 - v 4 yFv ) (2-1) K r V --, ~ V F F j