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Sample records for primary systemic al

  1. Concomitant diagnosis of primary Sjögren's syndrome and systemic AL amyloidosis.

    PubMed

    Delèvaux, I; André, M; Amoura, Z; Kémény, J L; Piette, J C; Aumaître, O

    2001-07-01

    A 48 year old woman was referred to hospital for buccal discomfort. Physical examination showed a macroglossia and features of xerostomia. She was diagnosed as having primary Sjögren's syndrome according to the criteria proposed by the European Community study group in 1993. Furthermore, a lower lip salivary gland biopsy showed amyloid deposits that were also seen in the stomach and in the bone marrow. Echocardiography was consistent with cardiac amyloidosis. Serum immunofixation identified a monoclonal IgGlambda. As far as is known, this is the first report of systemic primary amyloidosis associated with Sjögren's syndrome. The relation between these two disorders is discussed.

  2. /Cu-Al System

    NASA Astrophysics Data System (ADS)

    Kish, Orel; Froumin, Natalya; Aizenshtein, Michael; Frage, Nachum

    2014-05-01

    Wettability and interfacial interaction of the Ta2O5/Cu-Al system were studied. Pure Cu does not wet the Ta2O5 substrate, and improved spreading is achieved when relatively a high fraction of the active element (~40 at.% Al) was added. The Al2O3 and AlTaO4 phases were observed at the Ta2O5/Cu-Al interface. A thermodynamic evaluation allowed us to suggest that the lack of wetting bellow 40 at.% Al is due to the presence of a native oxide, which covers the drop. The conditions of the native oxide decomposition and the formation of the volatile Al2O suboxide strongly depend on the vacuum level during sessile drop experiments and the composition of the Cu-Al alloy. In our case, Al contents greater than 40% provides thermodynamic conditions for the formation of Al2O (as a result of Al reaction with Al2O3) and the drop spreading. It was suggested that the final contact angle in the Ta2O5/Cu-Al system (50°) is determined by Ta adsorption on the newly formed alumina interlayer.

  3. ALS superbend magnet system

    SciTech Connect

    Zbasnik, J.; Wang, S.T.; Chen, J.Y.; DeVries, G.J.; DeMarco, R.; Fahmie, M.; Geyer, A.; Green, M.A.; Harkins, J.; Henderson, T.; Hinkson, J.; Hoyer, E.H.; Krupnick, J.; Marks, S.; Ottens, F.; Paterson, J.A.; Pipersky, P.; Portmann, G.; Robin, D.A.; Schlueter, R.D.; Steier, C.; Taylor, C.E.; Wahrer, R.

    2000-09-15

    The Lawrence Berkeley National Laboratory is preparing to upgrade the Advanced Light Source (ALS) with three superconducting dipoles (Superbends). In this paper we present the final magnet system design which incorporates R&D test results and addresses the ALS operational concerns of alignment, availability, and economy. The design incorporates conduction-cooled Nb-Ti windings and HTS current leads, epoxy-glass suspension straps, and a Gifford-McMahon cryocooler to supply steady state refrigeration. We also present the current status of fabrication and testing.

  4. Long-term outcomes of primary systemic light chain (AL) amyloidosis in patients treated upfront with bortezomib or lenalidomide and the importance of risk adapted strategies.

    PubMed

    Kastritis, Efstathios; Roussou, Maria; Gavriatopoulou, Maria; Migkou, Magdalini; Kalapanida, Despina; Pamboucas, Constantinos; Kaldara, Elisavet; Ntalianis, Argyrios; Psimenou, Erasmia; Toumanidis, Savvas T; Tasidou, Anna; Terpos, Evangelos; Dimopoulos, Meletios A

    2015-04-01

    Bortezomib and lenalidomide are increasingly used in patients with AL amyloidosis, but long term data on their use as primary therapy in AL amyloidosis are lacking while early mortality remains significant. Thus, we analyzed the long term outcomes of 85 consecutive unselected patients, which received primary therapy with bortezomib or lenalidomide and we prospectively evaluated a risk adapted strategy based on bortezomib/dexamethasone to reduce early mortality. Twenty-six patients received full-dose bortezomib/dexamethasone, 36 patients lenalidomide with oral cyclophosphamide and low-dose dexamethasone and 23 patients received bortezomib/dexamethasone at a dose and schedule adjusted to the risk of early death. On intent to treat, 67% of patients achieved a hematologic response (24% hemCRs) and 34% an organ response; both were more frequent with bortezomib. An early death occurred in 20%: in 36% of those treated with full-dose bortezomib/dexamethasone, in 22% of lenalidomide-treated patients but only in 4.5% of patients treated with risk-adapted bortezomib/dexamethasone. Activity of full vs. adjusted dose bortezomib/dexamethasone was similar; twice weekly vs. weekly administration of bortezomib also had similar activity. After a median follow up of 57 months, median survival is 47 months and is similar for patients treated with bortezomib vs. lenalidomide-based regimens. However, risk adjusted-bortezomib/dexamethasone was associated with improved 1-year survival vs. full-dose bortezomib/dexamethasone or lenalidomide-based therapy (81% vs. 56% vs. 53%, respectively). In conclusion, risk-adapted bortezomib/dexamethasone may reduce early mortality and preserve activity while long term follow up indicates that remissions obtained with lenalidomide or bortezomib may be durable, even without consolidation with alkylators.

  5. Dynamic Modeling of ALS Systems

    NASA Technical Reports Server (NTRS)

    Jones, Harry

    2002-01-01

    The purpose of dynamic modeling and simulation of Advanced Life Support (ALS) systems is to help design them. Static steady state systems analysis provides basic information and is necessary to guide dynamic modeling, but static analysis is not sufficient to design and compare systems. ALS systems must respond to external input variations and internal off-nominal behavior. Buffer sizing, resupply scheduling, failure response, and control system design are aspects of dynamic system design. We develop two dynamic mass flow models and use them in simulations to evaluate systems issues, optimize designs, and make system design trades. One model is of nitrogen leakage in the space station, the other is of a waste processor failure in a regenerative life support system. Most systems analyses are concerned with optimizing the cost/benefit of a system at its nominal steady-state operating point. ALS analysis must go beyond the static steady state to include dynamic system design. All life support systems exhibit behavior that varies over time. ALS systems must respond to equipment operating cycles, repair schedules, and occasional off-nominal behavior or malfunctions. Biological components, such as bioreactors, composters, and food plant growth chambers, usually have operating cycles or other complex time behavior. Buffer sizes, material stocks, and resupply rates determine dynamic system behavior and directly affect system mass and cost. Dynamic simulation is needed to avoid the extremes of costly over-design of buffers and material reserves or system failure due to insufficient buffers and lack of stored material.

  6. Revealing heterogeneous nucleation of primary Si and eutectic Si by AlP in hypereutectic Al-Si alloys

    PubMed Central

    Li, Jiehua; Hage, Fredrik S.; Liu, Xiangfa; Ramasse, Quentin; Schumacher, Peter

    2016-01-01

    The heterogeneous nucleation of primary Si and eutectic Si can be attributed to the presence of AlP. Although P, in the form of AlP particles, is usually observed in the centre of primary Si, there is still a lack of detailed investigations on the distribution of P within primary Si and eutectic Si in hypereutectic Al-Si alloys at the atomic scale. Here, we report an atomic-scale experimental investigation on the distribution of P in hypereutectic Al-Si alloys. P, in the form of AlP particles, was observed in the centre of primary Si. However, no significant amount of P was detected within primary Si, eutectic Si and the Al matrix. Instead, P was observed at the interface between the Al matrix and eutectic Si, strongly indicating that P, in the form of AlP particles (or AlP ‘patch’ dependent on the P concentration), may have nucleated on the surface of the Al matrix and thereby enhanced the heterogeneous nucleation of eutectic Si. The present investigation reveals some novel insights into heterogeneous nucleation of primary Si and eutectic Si by AlP in hypereutectic Al-Si alloys and can be used to further develop heterogeneous nucleation mechanisms based on adsorption. PMID:27120994

  7. Revealing heterogeneous nucleation of primary Si and eutectic Si by AlP in hypereutectic Al-Si alloys

    NASA Astrophysics Data System (ADS)

    Li, Jiehua; Hage, Fredrik S.; Liu, Xiangfa; Ramasse, Quentin; Schumacher, Peter

    2016-04-01

    The heterogeneous nucleation of primary Si and eutectic Si can be attributed to the presence of AlP. Although P, in the form of AlP particles, is usually observed in the centre of primary Si, there is still a lack of detailed investigations on the distribution of P within primary Si and eutectic Si in hypereutectic Al-Si alloys at the atomic scale. Here, we report an atomic-scale experimental investigation on the distribution of P in hypereutectic Al-Si alloys. P, in the form of AlP particles, was observed in the centre of primary Si. However, no significant amount of P was detected within primary Si, eutectic Si and the Al matrix. Instead, P was observed at the interface between the Al matrix and eutectic Si, strongly indicating that P, in the form of AlP particles (or AlP ‘patch’ dependent on the P concentration), may have nucleated on the surface of the Al matrix and thereby enhanced the heterogeneous nucleation of eutectic Si. The present investigation reveals some novel insights into heterogeneous nucleation of primary Si and eutectic Si by AlP in hypereutectic Al-Si alloys and can be used to further develop heterogeneous nucleation mechanisms based on adsorption.

  8. Viking orbiter system primary mission

    NASA Technical Reports Server (NTRS)

    Goudy, J. R.

    1977-01-01

    An overview of Viking Orbiter (VO) system and subsystem performances during the primary mission (the time period from VO-1 launch on August 20, 1975, through November 15, 1976) is presented. Brief descriptions, key design requirements, pertinent historical information, unique applications or situations, and predicted versus actual performances are included for all VO-1 and VO-2 subsystems, both individually and as an integrated system.

  9. Al Qaeda as a System

    DTIC Science & Technology

    2006-03-15

    either as welcome guests or parasites . As welcome guests, Al Qaeda members take sanctuary in sponsor states. Sponsor states provide Al Qaeda with...sponsorship, Al Qaeda takes sanctuary as parasites either overtly or covertly. They take overt sanctuary in countries that publicly claim a policy...39 Yehudit Barsky, “Al Qa’ida, Iran, and Hezbollah: A Continuing Symbiosis ,” The American Jewish Committee Series on Terrorism , February 2004, 2-3

  10. Neuronal inclusion protein TDP-43 has no primary genetic role in FTD and ALS.

    PubMed

    Gijselinck, Ilse; Sleegers, Kristel; Engelborghs, Sebastiaan; Robberecht, Wim; Martin, Jean-Jacques; Vandenberghe, Rik; Sciot, Raf; Dermaut, Bart; Goossens, Dirk; van der Zee, Julie; De Pooter, Tim; Del-Favero, Jurgen; Santens, Patrick; De Jonghe, Peter; De Deyn, Peter P; Van Broeckhoven, Christine; Cruts, Marc

    2009-08-01

    The nuclear TAR DNA binding protein (TDP-43) is deposited in ubiquitin-positive inclusions in frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS), two clinicopathologically overlapping neurodegenerative diseases. In this study we excluded mutations and copy number variations in the gene encoding TDP-43 (TARDBP) from an extended series of 173 FTD and 237 ALS patients. Further, we did not identify association of common genetic variants in these patients. Our data implicate that TDP-43 has no primary genetic role in the pathophysiological mechanisms underlying central nervous system neurodegeneration in these diseases.

  11. Primary Atomic Clock Reference System

    NASA Technical Reports Server (NTRS)

    2001-01-01

    An artist's concept of the Primary Atomic Clock Reference System (PARCS) plarned to fly on the International Space Station (ISS). PARCS will make even more accurate atomic time available to everyone, from physicists testing Einstein's Theory of Relativity, to hikers using the Global Positioning System to find their way. In ground-based atomic clocks, lasers are used to cool and nearly stop atoms of cesium whose vibrations are used as the time base. The microgravity of space will allow the atoms to be suspended in the clock rather than circulated in an atomic fountain, as required on Earth. PARCS is being developed by the Jet Propulsion Laboratory with principal investigators at the National Institutes of Standards and Technology and the University of Colorado, Boulder. See also No. 0103191

  12. Primary Atomic Clock Reference System

    NASA Technical Reports Server (NTRS)

    2001-01-01

    An artist's concept of the Primary Atomic Clock Reference System (PARCS) plarned to fly on the International Space Station (ISS). PARCS will make even more accurate atomic time available to everyone, from physicists testing Einstein's Theory of Relativity, to hikers using the Global Positioning System to find their way. In ground-based atomic clocks, lasers are used to cool and nearly stop atoms of cesium whose vibrations are used as the time base. The microgravity of space will allow the atoms to be suspended in the clock rather than circulated in an atomic fountain, as required on Earth. PARCS is being developed by the Jet Propulsion Laboratory with principal investigators at the National Institutes of Standards and Technology and the University of Colorado, Boulder. See also No. 0100120.

  13. Job satisfaction among primary health care physicians and nurses in Al-madinah Al-munawwara.

    PubMed

    Al Juhani, Abdullah M; Kishk, Nahla A

    2006-01-01

    Job satisfaction is the affective orientation that an employee has towards his work. Greater physician satisfaction is associated with greater patient adherence and satisfaction. Nurses' job satisfaction, have great impact on the organizational success. Knowing parts of job dissatisfaction among physicians and nurses is important in forming strategies for retaining them in primary health care (PHC) centers. Therefore, this study aimed at assessing the level of job satisfaction among PHC physicians and nurses in Al- Madina Al- Munawwara. Also, to explore the relationship of their personal and job characteristics with job satisfaction. A descriptive cross- sectional epidemiological approach was adopted. A self completion questionnaire was distributed to physicians and nurses at PHC centers. A multi-dimensional job scale adopted by Traynor and Wade (1993) was modified and used. The studied sample included 445 health care providers, 23.6% were physicians and 76.4% were nurses. Job dissatisfaction was highly encountered where 67.1% of the nurses & 52.4% of physicians were dissatisfied. Professional opportunities, patient care and financial reward were the most frequently encountered domains with which physicians were dissatisfied. The dissatisfying domains for majority of nurses were professional opportunities, workload and appreciation reward. Exploring the relation between demographic and job characteristics with job satisfaction revealed that older, male, non-Saudi, specialists physicians had insignificantly higher mean score of job satisfaction than their counterparts. While older, female, non-Saudi, senior nurses had significantly higher mean score than their counterparts. It is highly recommended to reduce workload for nurses and provision of better opportunities promotional for PHC physicians and nurses.

  14. Systems Engineering Techniques for ALS Decision Making

    NASA Technical Reports Server (NTRS)

    Rodriquez, Luis F.; Drysdale, Alan E.; Jones, Harry; Levri, Julie A.

    2004-01-01

    The Advanced Life Support (ALS) Metric is the predominant tool for predicting the cost of ALS systems. Metric goals for the ALS Program are daunting, requiring a threefold increase in the ALS Metric by 2010. Confounding the problem, the rate new ALS technologies reach the maturity required for consideration in the ALS Metric and the rate at which new configurations are developed is slow, limiting the search space and potentially giving the perspective of a ALS technology, the ALS Metric may remain elusive. This paper is a sequel to a paper published in the proceedings of the 2003 ICES conference entitled, "Managing to the metric: an approach to optimizing life support costs." The conclusions of that paper state that the largest contributors to the ALS Metric should be targeted by ALS researchers and management for maximum metric reductions. Certainly, these areas potentially offer large potential benefits to future ALS missions; however, the ALS Metric is not the only decision-making tool available to the community. To facilitate decision-making within the ALS community a combination of metrics should be utilized, such as the Equivalent System Mass (ESM)-based ALS metric, but also those available through techniques such as life cycle costing and faithful consideration of the sensitivity of the assumed models and data. Often a lack of data is cited as the reason why these techniques are not considered for utilization. An existing database development effort within the ALS community, known as OPIS, may provide the opportunity to collect the necessary information to enable the proposed systems analyses. A review of these additional analysis techniques is provided, focusing on the data necessary to enable these. The discussion is concluded by proposing how the data may be utilized by analysts in the future.

  15. HYPERTENSION CARE IN AL ASYAH PRIMARY HEALTH CARE CENTER, AL QASSIM, SAUDI ARABIA: AN AUDIT OF STRUCTURE, PROCESS, AND OUTCOME

    PubMed Central

    Surour, Atef M.; Saleh, Mahmoud A.; Al-Alfi, Mohammed A.; Al-Saigul, Abdullah M.; Riyadh, Mohammed A.

    2004-01-01

    Objectives: The objective of this study is to assess the quality of hypertension care in Al-Asyah primary health cares (PHC) center, Al Qassim Region, Saudi Arabia through an auditing of structure, process, and outcome. Subjects and methods: All files of registered hypertensive patients in the PHC center were reviewed as recommended by WHO, National Quality Assurance protocol, protocol of management of hypertension and criteria in the Sixth report of Joint National Committee on detection, evaluation and treatment of high blood pressure (JNCVI), to evaluate the structure, process, and outcome of hypertension care. Result: All hypertensive patients registered in Al Asyah PHC center ( 201 patients ) were included in this study. The prevalence of HTN among adults (≥15 years) was7.4% and increased with age. Patients were mostly Saudi (94.5%) with a mean age of 58.6 ± 13.9 years. Most of the patients were diagnosed as essential HTN (98.5%) at Al Asyah PHC center (87.1%). The mean duration of the HTN was 7.7 years, and 48.8% had a family history of HTN and 35.3% had diabetes mellitus. Most patients were obese or overweight (53.7% and 31.3% respectively), blood pressure of 79.6% of the patients was well controlled, and 45.3% of these patients had at least one complication. Ischemic heart disease, left ventricular hypertrophy, stroke, and myocardial infarction were the most common recorded complications. Conclusion: This study proves that all essential resources needed for hypertension care are available, but the results of process and outcome indicators show the need for the improvement of the referral system as well as good continuous constant health education programs to encourage the patients, their families and the community to observe more healthy lifestyles. PMID:23012041

  16. Preoperational test report, primary ventilation system

    SciTech Connect

    Clifton, F.T.

    1997-11-04

    This represents a preoperational test report for Primary Ventilation Systems, Project W-030. Project W-030 provides a ventilation upgrade for the four Aging Waste Facility tanks. The system provides vapor space filtered venting of tanks AY101, AY102, AZ101, AZ102. The tests verify correct system operation and correct indications displayed by the central Monitor and Control System.

  17. Refinement of primary Si grains in Al-20%Si alloy slurry through serpentine channel pouring process

    NASA Astrophysics Data System (ADS)

    Zheng, Zhi-kai; Mao, Wei-min; Liu, Zhi-yong; Wang, Dong; Yue, Rui

    2016-05-01

    In this study, a serpentine channel pouring process was used to prepare the semi-solid Al-20%Si alloy slurry and refine primary Si grains in the alloy. The effects of the pouring temperature, number of curves in the serpentine channel, and material of the serpentine channel on the size of primary Si grains in the semi-solid Al-20%Si alloy slurry were investigated. The results showed that the pouring temperature, number of the curves, and material of the channel strongly affected the size and distribution of the primary Si grains. The pouring temperature exerted the strongest effect, followed by the number of the curves and then the material of the channel. Under experimental conditions of a four-curve copper channel and a pouring temperature of 701°C, primary Si grains in the semi-solid Al-20%Si alloy slurry were refined to the greatest extent, and the lath-like grains were changed into granular grains. Moreover, the equivalent grain diameter and the average shape coefficient of primary Si grains in the satisfactory semi-solid Al-20%Si alloy slurry were 24.4 μm and 0.89, respectively. Finally, the refinement mechanism and distribution rule of primary Si grains in the slurry prepared through the serpentine channel pouring process were analyzed and discussed.

  18. Mechanistic Selection and Growth of Twinned Bicrystalline Primary Si in Near Eutectic Al-Si Alloys

    SciTech Connect

    Jung, Choonho

    2006-01-01

    Morphological evolution and selection of angular primary silicon is investigated in near-eutectic Al-Si alloys. Angular silicon arrays are grown directionally in a Bridgman furnace at velocities in the regime of 10-3 m/sec and with a temperature gradient of 7.5 x 103 K/m. Under these conditions, the primary Si phase grows as an array of twinned bicrystalline dendrites, where the twinning gives rise to a characteristic 8-pointed star-shaped primary morphology. While this primary Si remains largely faceted at the growth front, a complex structure of coherent symmetric twin boundaries enables various adjustment mechanisms which operate to optimize the characteristic spacings within the primary array. In the work presented here, this primary silicon growth morphology is examined in detail. In particular, this thesis describes the investigation of: (1) morphological selection of the twinned bicrystalline primary starshape morphology; (2) primary array behavior, including the lateral propagation of the starshape grains and the associated evolution of a strong <100> texture; (3) the detailed structure of the 8-pointed star-shaped primary morphology, including the twin boundary configuration within the central core; (4) the mechanisms of lateral propagation and spacing adjustment during array evolution; and (5) the thermosolutal conditions (i.e. operating state) at the primary growth front, including composition and phase fraction in the vicinity of the primary tip.

  19. Primary systemic amyloidosis presenting as constrictive pericarditis.

    PubMed

    Singh, Vikas; Fishman, Joel E; Alfonso, Carlos E

    2011-01-01

    The most frequent presentation of cardiac amyloidosis is with endomyocardial deposition, and resultant restrictive cardiomyopathy. We present a case of primary systemic amyloidosis causing constrictive pericarditis (CP) and congestive heart failure without clinical evidence of endomyocardial deposition. A comprehensive evaluation by noninvasive and invasive studies facilitated the differentiation of CP from restrictive cardiomyopathy and the patient was effectively treated with pericardectomy. To our knowledge, this is the first documented case of primary systemic amyloidosis causing selective CP with successful antemortem diagnosis and treatment in a young man.

  20. Advanced Launch System (ALS): Electrical actuation and power systems improve operability and cost picture

    NASA Technical Reports Server (NTRS)

    Sundberg, Gale R.

    1990-01-01

    To obtain the Advanced Launch System (ALS) primary goals of reduced costs and improved operability, there must be significant reductions in the launch operations and servicing requirements relative to current vehicle designs and practices. One of the primary methods for achieving these goals is by using vehicle electrical power system and controls for all actuation and avionics requirements. A brief status review of the ALS and its associated Advanced Development Program is presented to demonstrate maturation of those technologies that will help meet the overall operability and cost goals. The electric power and actuation systems are highlighted as a specific technology ready not only to meet the stringent ALS goals (cryogenic field valves and thrust vector controls with peak power demands to 75 hp), but also those of other launch vehicles, military and civilian aircraft, lunar/Martian vehicles, and a multitude of commercial applications.

  1. Advanced Launch System (ALS) actuation and power systems impact operability and cost

    NASA Technical Reports Server (NTRS)

    Sundberg, Gale R.

    1990-01-01

    To obtain the Advanced Launch System (ALS) primary goals of reduced costs and improved operability, there must be significant reductions in the launch operations and servicing requirements relative to current vehicle designs and practices. One of the primary methods for achieving these goals is by using vehicle electrical power system and controls for all actuation and avionics requirements. A brief status review of the ALS and its associated Advanced Development Program is presented to demonstrate maturation of those technologies that will help meet the overall operability and cost goals. The electric power and actuation systems are highlighted as a specific technology ready not only to meet the stringent ALS goals (cryogenic field valves and thrust vector controls with peak power demands to 75 hp), but also those of other launch vehicles, military and civilian aircraft, lunar/Martian vehicles, and a multitude of commercial applications.

  2. Advanced launch system (ALS) - Electrical actuation and power systems improve operability and cost picture

    NASA Technical Reports Server (NTRS)

    Sundberg, Gale R.

    1990-01-01

    To obtain the Advanced Launch System (ALS) primary goals of reduced costs and improved operability, there must be significant reductions in the launch operations and servicing requirements relative to current vehicle designs and practices. One of the primary methods for achieving these goals is by using vehicle electrrical power system and controls for all aviation and avionics requirements. A brief status review of the ALS and its associated Advanced Development Program is presented to demonstrate maturation of those technologies that will help meet the overall operability and cost goals. The electric power and actuation systems are highlighted as a sdpecific technology ready not only to meet the stringent ALS goals (cryogenic field valves and thrust vector controls with peak power demands to 75 hp), but also those of other launch vehicles, military ans civilian aircraft, lunar/Martian vehicles, and a multitude of comercial applications.

  3. Project Design Concept Primary Ventilation System

    SciTech Connect

    MCGREW, D.L.

    2000-10-02

    Tank Farm Restoration and Safe Operation (TFRSO), Project W-3 14 was established to provide upgrades that would improve the reliability and extend the system life of portions of the waste transfer, electrical, ventilation, instrumentation and control systems for the Hanford Site Tank Farms. An assessment of the tank farm system was conducted and the results are documented in system assessment reports. Based on the deficiencies identified in the tank farm system assessment reports, and additional requirements analysis performed in support of the River Protection Project (RPP), an approved scope for the TFRSO effort was developed and documented in the Upgrade Scope Summary Report (USSR), WHC-SD-W314-RPT-003, Rev. 4. The USSR establishes the need for the upgrades and identifies the specific equipment to be addressed by this project. This Project Design Concept (PDC) is in support of the Phase 2 upgrades and provides an overall description of the operations concept for the W-314 Primary Ventilation Systems. Actual specifications, test requirements, and procedures are not included in this PDC. The PDC is a ''living'' document, which will be updated throughout the design development process to provide a progressively more detailed description of the W-314 Primary Ventilation Systems design. The Phase 2 upgrades to the Primary Ventilation Systems shall ensure that the applicable current requirements are met for: Regulatory Compliance; Safety; Mission Requirements; Reliability; and Operational Requirements.

  4. Challenging mimickers of primary systemic vasculitis.

    PubMed

    Miloslavsky, Eli M; Stone, John H; Unizony, Sebastian H

    2015-01-01

    The need to distinguish true primary systemic vasculitis from its multiple potential mimickers is one of the most challenging diagnostic conundrums in clinical medicine. This article reviews 9 challenging vasculitis mimickers: fibromuscular dysplasia, calciphylaxis, segmental arterial mediolysis, antiphospholipid syndrome, hypereosinophilic syndrome, lymphomatoid granulomatosis, malignant atrophic papulosis, livedoid vasculopathy, and immunoglobulin G4-related disease.

  5. [Transforming health systems based on primary care].

    PubMed

    Durán-Arenas, Luis; Salinas-Escudero, Guillermo; Granados-García, Víctor; Martínez-Valverde, Silvia

    2012-01-01

    Access to health services is a social basic determinant of health in Mexico unlike what happens in developed countries. The demand for health services is focused on primary care, but the design meets only the supply of hospital care services. So it generates a dissonance between the needs and the effective design of health services. In addition, the term affiliation refers to population contributing or in the recruitment process, that has been counted as members of these social security institutions (SS) and Popular Insurance (SP). In the case of Instituto Mexicano del Seguro Social (IMSS) three of four contributors are in contact with health services; while in the SP, this indicator does not exist. Moreover, the access gap between health services is found in the health care packages so that members of the SS and SP do not have same type of coverage. The question is: which model of health care system want the Mexicans? Primary care represents the first choice for increasing the health systems performance, as well as to fulfill their function of social protection: universal access and coverage based on needs, regardless whether it is a public or private health insurance. A central aspect for development of this component is the definition of the first contact with the health system through the creation of a primary health care team, led by a general practitioner as the responsible of a multidisciplinary health team. The process addresses the concepts of primary care nursing, consumption of inputs (mainly medical drugs), maintenance and general services. Adopting a comprehensive strategy that will benefit all Mexicans equally and without discrimination, this primary care system could be financed with a total operating cost of approximately $ 22,809 million by year.

  6. Evaluating Primary Dendrite Trunk Diameters in Directionally Solidified Al-Si Alloys

    NASA Technical Reports Server (NTRS)

    Grugel, R. N.; Tewari, S. N.; Poirier, D. R.

    2014-01-01

    The primary dendrite trunk diameters of Al-Si alloys that were directionally solidified over a range of processing conditions have been measured. These data are analyzed with a model based primarily on an assessment of secondary dendrite arm dissolution in the mushy zone. Good fit with the experimental data is seen and it is suggested that the primary dendrite trunk diameter is a useful metric that correlates well with the actual solidification processing parameters. These results are placed in context with the limited results from the aluminium - 7 wt. % silicon samples directionally solidified aboard the International Space Station as part of the MICAST project.

  7. Realization of a primary spectrophotometric system

    NASA Astrophysics Data System (ADS)

    Škerović, V.; Vukadin, P.; Zarubica, V.; Zeković, Lj

    2008-08-01

    The first step in establishing measurement uniformity in spectrophotometry is the realization of a versatile, fully evaluated and documented measurement system, which may, after metrological validation, be upheld as the primary spectrophotometric standard. In this paper, the development and realization of the spectrophotometer—primary standard in the Laboratory for Photometry of Bureau of Measures and Precious Metals—are presented. The construction of the system, as well as its metrological characterization, is shown. Evaluation of systematic errors due to various influential quantities and physical effects, such as light beam geometry effects, inter-reflections, nonlinearities and others, is presented. The results of measurements of spectral transmittance made with neutral optical filters and the evaluation of total measurement uncertainty are presented. Validation of the results was preformed according to National Institute for Standards and Technologies (NIST) certified standards of spectral transmittance.

  8. Systemic primary carnitine deficiency with hypoglycemic encephalopathy

    PubMed Central

    Jun, Jae Sung; Lee, Eun Joo; Park, Hyung Doo

    2016-01-01

    Acute hypoglycemia in children is not an uncommon disease that can be encountered in the Emergency Department. Most cases of childhood hypoglycemia are caused by ketotic hypoglycemia due to missed meals. Often, hypoketotic hypoglycemia can also occur, which suggests hyperinsulinemia or a defect in fatty acid oxidation. Carnitine is essential for long chain fatty acids transfer into mitochondria for oxidation. We present a case of systemic primary carnitine deficiency who presented with seizures due to hypoketotic hypoglycemia. PMID:28164076

  9. Outlier Benchmark Systems With Gaia Primaries

    NASA Astrophysics Data System (ADS)

    Marocco, Federico; Pinfield, David J.; Montes, David; Zapatero Osorio, Maria Rosa; Smart, Richard L.; Cook, Neil J.; Caballero, José A.; Jones, Hugh, R. A.; Lucas, Phil W.

    2016-07-01

    Benchmark systems are critical to assisting sub-stellar physics. While the known population of benchmarks hasincreased significantly in recent years, large portions of the age-metallicity parameter space remain unexplored.Gaia will expand enormously the pool of well characterized primary stars, and our simulations show that we couldpotentially have access to more than 6000 benchmark systems out to 300 pc, allowing us to whittle down thesenbsp;systems into a large sample with outlier properties that will reveal the nature of ultra-cool dwarfs in rare parameternbsp;space. In this contribution we present the preliminary results from our effort to identify and characterize ultra-coolnbsp;companions to Gaia-imaged stars with unusual values of metallicity. Since these systems are intrinsically rare, wenbsp;expand the volume probed by targeting faint, low-proper motion systems.nbsp;/p>

  10. REPOSITORY SURFACE FACILITIES PRIMARY SYSTEM CRANE DATA

    SciTech Connect

    K. Schwartztrauber

    2005-03-14

    The purpose of this calculation is to compile crane design data for the mechanical primary structures, systems, and components (SSCs) required for the repository Waste Handling Building (WHB) and Carrier Preparation Building (CPB). The work presented in this document has been prepared in accordance with Office of Civilian Radioactive Waste Management approved program document AP-3.12Q, Calculations. This calculation has been developed to supplement information previously prepared using the development plan for ''WHB/WTB Space Program Analysis for Site Recommendation'' (Reference 5), which concentrates on the primary, primary support, facility support, and miscellaneous building support areas located in the WHB and Waste Treatment Building (WTB). The development plan was completed in accordance with AP-2.13Q, ''Technical Product Development Planning''. The work in this calculation is a continuance of the work described in the previous development plan; therefore, in accordance with AP-2.21Q, ''Quality Determinations and Planning for Scientific, Engineering, and Regulatory Compliance Activities'', a new Technical Work Plan is not required.

  11. Phase diagrams of Al-Si and Al-Ge systems

    NASA Astrophysics Data System (ADS)

    Kagaya, Hiroko-Matsuo; Imazawa, Kazumoto; Sato, Mayumi; Soma, Toshinobu

    1998-03-01

    Considering the contributions from the band and local mode frequencies, the temperature- and pressure-dependent mean-square displacement for Al-Si and Al-Ge solid solutions is quantitatively calculated to be similar to that for matrix Al. Then, the concentration-dependence of the Debye temperature at higher and lower temperatures is estimated, the pressure effect on the solidus curve is presented by applying Lindeman's melting law to the Al-Si and Al-Ge alloy systems. The solidus curve obtained increases as a function of the pressure, and is in good agreement with the observed tendency for these solid solutions.

  12. 77 FR 40250 - Tart Cherries Grown in the States of Michigan, et al.; Increasing the Primary Reserve Capacity...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-09

    ... Agricultural Marketing Service 7 CFR Part 930 Tart Cherries Grown in the States of Michigan, et al.; Increasing the Primary Reserve Capacity and Revising Exemption Requirements AGENCY: Agricultural Marketing... the exemption provisions applicable to handler diversion activities prescribed under the...

  13. Primary helium heater for propellant pressurization systems

    NASA Technical Reports Server (NTRS)

    Reichmuth, D. M.; Nguyen, T. V.; Pieper, J. L.

    1991-01-01

    The primary helium heater is a unique design that provides direct heating of pressurant gas for large pressure fed propulsion systems. It has been conceptually designed to supply a heated (800-1000 R) pressurization gas to both a liquid oxygen and an RP-1 propellant tank. This pressurization gas is generated within the heater by mixing super critical helium (40-300 R and 3000-1600 psi) with an appropriate amount of combustion products from a 4:1 throttling stoichiometric LO2/LH2 combustor. This simple, low cost and reliable mixer utilizes the large quantity of helium to provide stoichiometric combustor cooling, extend the throttling limits and enhance the combustion stability margin. Preliminary combustion, thermal, and CFD analyses confirm that this low-pressure-drop direct helium heater can provide the constant-temperature pressurant suitable for tank pressurization of both fuel and oxidizer tanks of large pressure fed vehicles.

  14. Primary reflector for solar energy collection systems

    NASA Technical Reports Server (NTRS)

    Miller, C. G. (Inventor); Stephens, J. B.

    1978-01-01

    A fixed, linear, ground-based primary reflector is disclosed which has an extended curved sawtooth-contoured surface covered with a metalized polymeric reflecting material. The device reflects solar energy to a movably supported collector that is kept at the concentrated line focus of the reflector primary. The primary reflector may be constructed by a process utilizing well-known freeway paving machinery.

  15. Primary central nervous system posttransplant lymphoproliferative disorders.

    PubMed

    Castellano-Sanchez, Amilcar A; Li, Shiyong; Qian, Jiang; Lagoo, Anand; Weir, Edward; Brat, Daniel J

    2004-02-01

    Posttransplant lymphoproliferative disorders (PTLDs) represent a spectrum ranging from Epstein-Barr virus (EBV)-driven polyclonal lymphoid proliferations to EBV+ or EBV- malignant lymphomas. Central nervous system (CNS) PTLDs have not been characterized fully. We reviewed the clinical, radiologic, and pathologic features of 12 primary CNS PTLDs to define them more precisely. Patients included 10 males and 2 females (median age, 43.4 years) who were recipients of kidney (n = 5), liver (n = 2), heart (n = 2), peripheral blood stem cells (n = 2), or bone marrow (n = 1). All received immunosuppressive therapy. CNS symptoms developed 3 to 131 months (mean, 31 months) after transplantation. By neuroimaging, most showed multiple (3 to 9) intra-axial, contrast-enhancing lesions. Histologic sections showed marked expansion of perivascular spaces by large, cytologically malignant lymphoid cells that were CD45+, CD20+, EBV+ and showed light chain restriction or immunoglobulin gene rearrangement. In distinction to PTLDs in other organ systems, CNS PTLDs were uniformly high-grade lymphomas that fulfilled the World Health Organization criteria for monomorphic PTLDs. Extremely short survival periods were noted for each CNS PTLD that followed peripheral blood stem cell transplantation. Survival of others with CNS PTLD varied; some lived more than 2 years.

  16. Pediatric primary care as a component of systems of care.

    PubMed

    Brown, Jonathan D

    2010-02-01

    Systems of care should be defined in a manner that includes primary care. The current definition of systems of care shares several attributes with the definition of primary care: both are defined as community-based services that are accessible, accountable, comprehensive, coordinated, culturally competent, and family focused. However, systems of care is defined as serving only children and youth with serious emotional disturbance and their families and does not fully embrace the concept of primary prevention. Although similarities in the definitions of primary care and systems of care may provide a theoretical foundation for including primary care within the systems of care framework, a definition of systems of care that incorporates the idea of prevention and takes into account the broad population served in primary care would provide communities with a definition that can be used to further the work of integrating primary care into systems of care.

  17. Development of Educational Management System in Small Primary School

    ERIC Educational Resources Information Center

    Alsammarry, Yupayao; Sirisuthi, Chaiyuth; Duangcharthom, Surat

    2016-01-01

    The purposes of the research were: (1) to study the factors of Educational Management System in Small Primary School; (2) to investigate current situations problems and guidelines of developing educational management in small primary school; (3) to develop Educational Management System in Small Primary School; and (4) to examine the results of…

  18. Primary Dendrite Arm Spacings in Al-7Si Alloy Directionally Solidified on the International Space Station

    NASA Technical Reports Server (NTRS)

    Angart, Samuel; Lauer, Mark; Poirier, David; Tewari, Surendra; Rajamure, Ravi; Grugel, Richard

    2015-01-01

    Samples from directionally solidified Al- 7 wt. % Si have been analyzed for primary dendrite arm spacing (lambda) and radial macrosegregation. The alloy was directionally solidified (DS) aboard the ISS to determine the effect of mitigating convection on lambda and macrosegregation. Samples from terrestrial DS-experiments thermal histories are discussed for comparison. In some experiments, lambda was measured in microstructures that developed during the transition from one speed to another. To represent DS in the presence of no convection, the Hunt-Lu model was used to represent diffusion controlled growth under steady-state conditions. By sectioning cross-sections throughout the entire length of a solidified sample, lambda was measured and calculated using the model. During steady-state, there was reasonable agreement between the measured and calculated lambda's in the space-grown samples. In terrestrial samples, the differences between measured and calculated lambda's indicated that the dendritic growth was influenced by convection.

  19. Quality of Diabetes Care in Primary Health Centres in North Al-Batinah of Oman

    PubMed Central

    Al-Shafaee, Mohammed; Al-Farsi, Yousuf; Al-Kaabi, Yousuf; Banerjee, Yajnavalka; Al-Zadjali, Najat; Al-Zakwani, Ibrahim

    2014-01-01

    Objective: To assess the quality of diabetic care provided in primary health care settings in Oman. Methods: This was a cross-sectional study of randomly selected 500 patients with diabetes mellitus (DM) attending 6 primary care diabetic clinics in the north Al-Batinah region of Oman from January to December 2010. Nine standards on the quality of diabetes care were audited. Results: The mean age of the sample was 51±13 years, ranging from 15 to 87 years; the majority (61%) were females. The mean duration of DM was 4±3 years, ranging from 1 to 18 years. Seventy-seven percent of the patients attended diabetic clinics at least 4 times per year. Of the 9 assessed diabetic standards, HbA1c was documented in 33% of the patients, body mass index in 12%, low-density lipoprotein cholesterol (LDL-C) in 40%, urinary albumin:creatinine ratio in 28%, creatinine in 63% and blood pressure (BP) in 96%. Optimal control among the documented indicators was noted in 32, 21, 25, 85, 95 and 19%, respectively. Twenty percent of the patients had their ECGs done while only 39% of the patients had foot examination. No patient had attained control in all of HbA1c., BP and LDL-C. Conclusion: There is a gap between the recommended DM care guidelines and current practice with consequent poor quality of care in these patients. PMID:25024774

  20. Solidification of Liquid Distributed in its Primary Matrix Phase of Al-10Cu-Fe Alloy and Their Tribological Characteristics

    NASA Astrophysics Data System (ADS)

    Rao, L. Sankara; Jha, A. K.; Ojha, S. N.

    2016-12-01

    Solidification behavior of liquid phase entrained in its primary solid has been investigated. A hypoeutectic alloy based on Al-Cu-Fe system containing Fe and Si was thermal cycled between semisolid regions to low temperatures. The freezing characteristics of the liquid were recorded in inverse rate cooling curves. The continuous network of the liquid phase progressively changed into isolated droplets with their different size and size distribution. Such droplets revealed undercooling of the melt varying from 20 to 35 °C below the eutectic temperature of the alloy. This behavior of melt undercooling is discussed in light of independent nucleation events associated with freezing of droplets. Solidification structure of droplets revealed particulate eutectic phases in contrast to lamellar eutectic microstructure in the interdendritic region of the as-cast alloy. The droplet distribution and their solidification structure resulted in an improvement in tribological characteristics of the alloy. This effect is correlated with features of wear surfaces generated on the matting surfaces.

  1. Solidification of Liquid Distributed in its Primary Matrix Phase of Al-10Cu-Fe Alloy and Their Tribological Characteristics

    NASA Astrophysics Data System (ADS)

    Rao, L. Sankara; Jha, A. K.; Ojha, S. N.

    2017-02-01

    Solidification behavior of liquid phase entrained in its primary solid has been investigated. A hypoeutectic alloy based on Al-Cu-Fe system containing Fe and Si was thermal cycled between semisolid regions to low temperatures. The freezing characteristics of the liquid were recorded in inverse rate cooling curves. The continuous network of the liquid phase progressively changed into isolated droplets with their different size and size distribution. Such droplets revealed undercooling of the melt varying from 20 to 35 °C below the eutectic temperature of the alloy. This behavior of melt undercooling is discussed in light of independent nucleation events associated with freezing of droplets. Solidification structure of droplets revealed particulate eutectic phases in contrast to lamellar eutectic microstructure in the interdendritic region of the as-cast alloy. The droplet distribution and their solidification structure resulted in an improvement in tribological characteristics of the alloy. This effect is correlated with features of wear surfaces generated on the matting surfaces.

  2. 'Abd al-Rahman al-Sufi's 3-Step Magnitude System

    NASA Astrophysics Data System (ADS)

    Hafez, Ihsan; Stephenson, F. Richard; Orchiston, Wayne

    'Abd al-Rahmān al-ūfī's Book of the Fixed Stars dates from around AD 964 and is one of the most important medieval Arabic treatises on astronomy. In this paper we begin with a very brief introduction to the Book of the Fixed Stars. This book contains an extensive star catalogue that lists star coordinates and magnitude estimates for all of the Ptolemaic stars. However, in his book al-hūfī utilized three distinct intermediate magnitude values whereas Ptolemy only mentioned two. We believe that al-hūfī used what we have termed a '3-step intermediate magnitude system,' which is more accurate than Ptolemy's 2-step intermediate system. In this paper we examine in detail the accuracy of this unique 3-step system in comparison with Ptolemy's and modern magnitude values.

  3. Teachers' Performance Motivation System in Thai Primary Schools

    ERIC Educational Resources Information Center

    Pasathang, Sarojn; Tesaputa, Kowat; Sataphonwong, Pattananusron

    2016-01-01

    This research aims to: 1) study the present conditions and desirable condition of the motivation systems as well as how to find methods for motivating the performance of teachers in primary schools, 2) develop a motivation system for the performance of teachers in primary schools, 3) study the effects of using the motivation system for compliance…

  4. Pediatric Primary Care as a Component of Systems of Care

    ERIC Educational Resources Information Center

    Brown, Jonathan D.

    2010-01-01

    Systems of care should be defined in a manner that includes primary care. The current definition of systems of care shares several attributes with the definition of primary care: both are defined as community-based services that are accessible, accountable, comprehensive, coordinated, culturally competent, and family focused. However, systems of…

  5. Investigation of Phase Equilibria and Some Properties of Alloys of Ti-Al-Fe and Ti-Al-V Systems,

    DTIC Science & Technology

    Some data on the structure and properties of Ti-Al-Fe alloys are presented. The phase equilibria in alloys in the system Ti-Al-V were studies...However, the data available in the literature on phase equilibria in the systems Ti-Al-Fe and Ti-Al-V require refinement, as they are insufficiently

  6. Thermodynamic Modeling of the Al-Cr-Mn Ternary System

    NASA Astrophysics Data System (ADS)

    Cui, Senlin; Jung, In-Ho

    2017-03-01

    The phase diagram information available in the literature on the Al-Cr-Mn system was comprehensively evaluated and optimized for the first time to obtain a set of Gibbs energies of all the solid and liquid phases in the Al-Cr-Mn system. The Modified Quasi-chemical Model (MQM) was utilized to describe the Gibbs energy of the liquid phase of the Al-Cr-Mn system. The Compound Energy Formalism (CEF) was used to model the solid solution phases. A revision of the Al-Mn system was simultaneously conducted to consider the γ_H (Al8Mn5) phase. The liquid Cr-Mn phase was also remodeled using the Modified Quasi-chemical Model (MQM) to obtain a consistent description of the ternary Al-Cr-Mn liquid phase. Accurate description of the phase diagram of the entire Al-Cr-Mn system was obtained from the thermodynamic models with optimized parameters in the present study, and the model parameters can be used to predict the thermodynamic properties of the ternary system.

  7. [Primary central nervous system lymphoma: report of one case].

    PubMed

    Zhao, Peng; Su, Rong-Gang

    2002-04-01

    One case of primary central nervous system lymphoma was reported. The patient received comprehensive therapy, mainly the surgical treatment, with the survival time 12 months, and local recurrence was considered as the major cause of death. The pathology, imagine examination, diagnosis and treatment of primary central nervous system lymphoma were discussed.

  8. Primary healthcare system and practice characteristics in Singapore.

    PubMed

    Khoo, Hwee Sing; Lim, Yee Wei; Vrijhoef, Hubertus Jm

    2014-01-01

    It is crucial to adapt and improve the (primary) health care systems of countries to prepare for future patient profiles and their related needs. The main aim of this study was to acquire a comprehensive overview of the perceptions of primary care experts in Singapore about the state of primary care in Singapore, and to compare this with the state of primary care in other countries. Notwithstanding ranked 2(nd) in terms of efficiency of health care, Singapore is facing significant health care challenges. Emails were sent to 85 experts, where they were asked to rate Singapore's primary care system based on nine internationally adopted health system characteristics and six practice characteristics (response rate = 29%). The primary care system in Singapore received an average of 10.9 out of 30 possible points. Lowest ratings were given to: earnings of primary care physicians compared to specialists, requirement for 24 hr accessibility of primary care services, standard of family medicine in academic departments, reflection of community served by practices in patient lists, and the access to specialists without needing to be referred by primary care physicians. Singapore was categorized as a 'low' primary care country according to the experts.

  9. Interdiffusion in the Mg-Al system and Intrinsic Diffusion in (Al3Mg2) Phase

    SciTech Connect

    Brennan, Sarah; Bermudez, Katrina; Kulkarni, Nagraj S; Sohn, Yong Ho

    2011-01-01

    Increasing use and development of lightweight Mg-alloys have led to the desire for more fundamental research in and understanding of Mg-based systems. As a strengthening component, Al is one of the most important and common alloying elements for Mg-alloys. In this study, solid-to-solid diffusion couple techniques were employed to examine the interdiffusion between pure Mg and Al. Diffusion anneals were carried out at 300 , 350 , and 400 C for 720, 360, and 240 hours, respectively. Optical and scanning electron microscopies (SEM) were employed to observe the formation of the intermetallics -Al12Mg17 and -Al3Mg2, but not -phase. Concentration profiles were determined using X-ray energy dispersive spectroscopy (XEDS). The growth constants and activation energies were determined for each intermetallic phase.

  10. Characteristics of primary electric propulsion systems. [conferences

    NASA Technical Reports Server (NTRS)

    Byers, D. C.

    1979-01-01

    The use of advanced electric propulsion systems is expected to provide cost and performance benefits for future energetic space missions. A methodology to predict the characteristics of advanced electric propulsion systems was developed and programmed for computer calculations to allow evaluation of a broad set of technology and mission assumptions. The impact on overall thrust system characteristics was assessed for variations of propellant type, total accelerating voltage, thruster area, specific impulse, and power system approach. The data may be used both to provide direction to technology emphasis and allow for preliminary estimates of electric propulsion system properties for a wide variety of applications.

  11. School Management Information Systems in Primary Schools

    ERIC Educational Resources Information Center

    Demir, Kamile

    2006-01-01

    Developments in information technologies have been impacting upon educational organizations. Principals have been using management information systems to improve the efficiency of administrative services. The aim of this research is to explore principals' perceptions about management information systems and how school management information…

  12. Primary care training and the evolving healthcare system.

    PubMed

    Peccoralo, Lauren A; Callahan, Kathryn; Stark, Rachel; DeCherrie, Linda V

    2012-01-01

    With growing numbers of patient-centered medical homes and accountable care organizations, and the potential implementation of the Patient Protection and Affordable Care Act, the provision of primary care in the United States is expanding and changing. Therefore, there is an urgent need to create more primary-care physicians and to train physicians to practice in this environment. In this article, we review the impact that the changing US healthcare system has on trainees, strategies to recruit and retain medical students and residents into primary-care internal medicine, and the preparation of trainees to work in the changing healthcare system. Recruitment methods for medical students include early preclinical exposure to patients in the primary-care setting, enhanced longitudinal patient experiences in clinical clerkships, and primary-care tracks. Recruitment methods for residents include enhanced ambulatory-care training and primary-care programs. Financial-incentive programs such as loan forgiveness may encourage trainees to enter primary care. Retaining residents in primary-care careers may be encouraged via focused postgraduate fellowships or continuing medical education to prepare primary-care physicians as both teachers and practitioners in the changing environment. Finally, to prepare primary-care trainees to effectively and efficiently practice within the changing system, educators should consider shifting ambulatory training to community-based practices, encouraging resident participation in team-based care, providing interprofessional educational experiences, and involving trainees in quality-improvement initiatives. Medical educators in primary care must think innovatively and collaboratively to effectively recruit and train the future generation of primary-care physicians.

  13. Application of Total Quality Management System in Thai Primary Schools

    ERIC Educational Resources Information Center

    Prueangphitchayathon, Setthiya; Tesaputa, Kowat; Somprach, Kanokorn

    2015-01-01

    The present study seeks to develop a total quality management (TQM) system that can be applied to primary schools. The approach focuses on customer orientation, total involvement of all constituencies and continuous improvement. TQM principles were studied and synthesized according to case studies of the best practices in 3 primary schools (small,…

  14. Primary Health Care in Canada: Systems in Motion

    PubMed Central

    Hutchison, Brian; Levesque, Jean-Frederic; Strumpf, Erin; Coyle, Natalie

    2011-01-01

    Context: During the 1980s and 1990s, innovations in the organization, funding, and delivery of primary health care in Canada were at the periphery of the system rather than at its core. In the early 2000s, a new policy environment emerged. Methods: This policy analysis examines primary health care reform efforts in Canada during the last decade, drawing on descriptive information from published and gray literature and from a series of semistructured interviews with informed observers of primary health care in Canada. Findings: Primary health care in Canada has entered a period of potentially transformative change. Key initiatives include support for interprofessional primary health care teams, group practices and networks, patient enrollment with a primary care provider, financial incentives and blended-payment schemes, development of primary health care governance mechanisms, expansion of the primary health care provider pool, implementation of electronic medical records, and quality improvement training and support. Conclusions: Canada's experience suggests that primary health care transformation can be achieved voluntarily in a pluralistic system of private health care delivery, given strong government and professional leadership working in concert. PMID:21676023

  15. Primary amoebic meningoencephalitis in a patient with systemic lupus erythematosus.

    PubMed

    Shrestha, Nabin K; Khanal, Basudha; Sharma, Sanjib K; Dhakal, Subodh S; Kanungo, Reba

    2003-01-01

    This report describes a case of primary amoebic meningoencephalitis in a patient with systemic lupus erythematosus. No specific exposure was identified. Treatment with intravenous amphotericin B was associated with marked clinical improvement, but subsequent fatal relapse while still on therapy.

  16. Crystal structure of novel compounds in the systems Zr-Cu-Al, Mo-Pd-Al and partial phase equilibria in the Mo-Pd-Al system.

    PubMed

    Khan, Atta U; Rogl, P; Giester, G

    2012-02-28

    The crystal structures of three Al-rich compounds have been solved from X-ray single crystal diffractometry: τ(1)-MoPd(2-x)Al(8+x) (x = 0.067); τ(7)-Zr(Cu(1-x)Al(x))(12) (x = 0.514) and τ(9)-ZrCu(1-x)Al(4) (x = 0.144). τ(1)-MoPd(2-x)Al(8+x) adopts a unique structure type (space group Pbcm; lattice parameters a = 0.78153(2), b = 1.02643(3) and c = 0.86098(2) nm), which can be conceived as a superstructure of the Mo(Cu(x)Al(1-x))(6)Al(4) type. Whereas Mo-atoms occupy the 4d site, Pd(2) occupies the 4c site, Al and Pd(1) atoms randomly share the 4d position and the rest of the positions are fully occupied by Al. A Bärnighausen tree documents the crystallographic group-subgroup relation between the structure types of Mo(Cu(x)Al(1-x))(6)Al(4) and τ(1). τ(7)-Zr(Cu(1-x)Al(x))(12) (x = 0.514) has been confirmed to crystallize with the ThMn(12) type (space group I4/mmm; lattice parameters a = 0.85243(2) and c = 0.50862(3) nm). In total, 4 crystallographic sites were defined, out of which, Zr occupies site 2a, the 8f site is fully occupied by Cu, the 8i site is entirely occupied by Al, but the 8j site turned out to comprise a random mixture of Cu and Al atoms. The compound τ(9)-ZrCu(1-x)Al(4) (x = 0.144) crystallizes in a unique structure type (space group P4/nmm; lattice parameters a = 0.40275(3) and c = 1.17688(4) nm) which exhibits full atom order but a vacancy (14.4%) on the 2c site, shared with Cu atoms. τ(9)-ZrCu(1-x)Al(4) is a superstructure of Cu with an arrangement of three unit cells of Cu in the direction of the c-axis. A Bärnighausen tree documents this relationship. The ZrCu(1-x)Al(4) type (n = 3) is part of a series of structures which follow this building principle: Cu (n = 1), TiAl(3) (n = 2), τ(5)-TiNi(2-x)Al(5) (n = 4), HfGa(2) (n = 6) and Cu(3)Pd (n = 7). A partial isothermal section for the Al-rich part of the Mo-Pd-Al system at 860 °C has been established with two ternary compounds τ(1)-MoPd(2-x)Al(8+x) and τ(2) (unknown structure). The

  17. 75 FR 65279 - Schedule for Rating Disabilities; AL Amyloidosis (Primary Amyloidosis)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-22

    ... presumptive service connection based on herbicide exposure for this disease. The intended effects are to... adding AL amyloidosis to the list of diseases associated with exposure to certain herbicide...

  18. Viking 75 project: Viking lander system primary mission performance report

    NASA Technical Reports Server (NTRS)

    Cooley, C. G.

    1977-01-01

    Viking Lander hardware performance during launch, interplanetary cruise, Mars orbit insertion, preseparation, separation through landing, and the primary landed mission, with primary emphasis on Lander engineering and science hardware operations, the as-flown mission are described with respect to Lander system performance and anomalies during the various mission phases. The extended mission and predicted Lander performance is discussed along with a summary of Viking goals, mission plans, and description of the Lander, and its subsystem definitions.

  19. 78 FR 28896 - Design Limits and Loading Combinations for Metal Primary Reactor Containment System Components

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-16

    ... COMMISSION Design Limits and Loading Combinations for Metal Primary Reactor Containment System Components... Combinations for Metal Primary Reactor Containment System Components,'' in which there are no substantive... loading combinations for metal primary reactor containment system components. ADDRESSES: Please refer...

  20. The 747 primary flight control systems reliability and maintenance study

    NASA Technical Reports Server (NTRS)

    1979-01-01

    The major operational characteristics of the 747 Primary Flight Control Systems (PFCS) are described. Results of reliability analysis for separate control functions are presented. The analysis makes use of a NASA computer program which calculates reliability of redundant systems. Costs for maintaining the 747 PFCS in airline service are assessed. The reliabilities and cost will provide a baseline for use in trade studies of future flight control system design.

  1. Faceted growth of primary Al{sub 2}Cu crystals during directional solidification in high magnetic field

    SciTech Connect

    Li, Chuanjun; Ren, Zhongming; Shen, Yu; Wang, Qiuliang; Dai, Yinming; Wang, Hui

    2013-10-21

    The high magnetic field is widely used to modify the crystal morphology. In this work, the effect of the magnetic field on growing behavior of faceted crystals in the Al-40 wt. %Cu alloy was investigated using directional solidification technique. It was found that the faceted growth of primary Al{sub 2}Cu phase was degraded and the primary spacing was reduced upon applying the magnetic field. Additionally, the length of the mushy zone first decreased and then increased with increase of the magnetic field intensity. The quantitative analysis reveals that the shear stress induced by the fluid motion is insufficient to break the atom bonds at the solid-liquid interface. However, both of the thermoelectric magnetic convection (TEMC) and the thermoelectric magnetic force (TEMF) cause dendrites to fracture and reduce the primary spacing. The two effects also weaken the faceting growth. Moreover, the instability of the solid-liquid interface is generated by the TEMF, which further leads to degrade the faceted growth. The length of mushy zone was changed by the TEMC and reached the minimum in the magnetic field of 0.5 T, which is in good agreement with the predicted value (0.83 T)

  2. An Assessment of the Al- Fe- N System

    NASA Astrophysics Data System (ADS)

    Hillert, Mats; Jonsson, Stefan

    1992-11-01

    The thermodynamic properties of the Al-Fe-N system are assessed, taking various types of information into account. For solid AIN, a description very similar to that given by JANAF is found to yield reasonable predictions for the solubility of A1N in face-centered cubic (fcc) Fe and in liquid Fe. An ionic two-sublattice model is applied to the liquid phase, containing two N species, N-3 and N0 The melting point of A1N is taken as 3068 K, and a required gas pressure of 9.75 bar is predicted. A sublimation point of 2690 K at 1 bar is also predicted. A plot of the liquidus surfaces in the Fe-rich end of the Al-Fe-N system is presented.

  3. Systemic AL amyloidosis in a Beech Marten (Martes foina).

    PubMed

    Scaglione, F E; Mignone, W; Ferrero, E; Poggi, M; Biolatti, B; Bollo, E

    2013-10-01

    A wild Beech Marten (Martes foina), was referred for necropsy to the Department of Animal Pathology of the University of Turin (Italy). At gross examination, whitish and firm masses, 10-mm in diameter, were found on the heart and in the kidney. Spleen showed lighter color and greater consistency, and the cut surface of the liver appeared scattered with whitish-yellow coalescing foci homogeneously distributed. Amyloid deposits were present in the perivascular and intercellular spaces of the visceral organs, such as the heart, liver, and kidneys. Amyloid stained positively with Congo red with and without 5% potassium permanganate pretreatment and showed green birefringence observable under polarized light. A diagnosis of systemic AL amyloidosis was made. This is the first description of systemic AL amyloidosis in a wild Stone Marten.

  4. Influence of the permeability of networked primary Si on the ejection of hypereutectic Al-Si melts by centrifugation

    NASA Astrophysics Data System (ADS)

    Youn, Ji Won; Jeon, Je-Beom; Park, Jin Man; Seo, Seok Yong; Lim, Jeon Taik; Kim, Suk Jun; Kim, Ki Young

    2017-02-01

    The separation of high purity Si for solar cells from Al-Si alloy melt in the mushy zone was investigated using an advanced centrifugal technique. The efficiency of separating Si, based on the weight ratio of separated Si to Si in alloy melt, was maximized by optimizing the permeability of a porous structure of Si (Si foam.) For the optimization of the permeability, two fundamental microstructure variables, size and the solid fraction of primary Si platelets, were controlled by adjusting the Si content in the melts and the rotation start temperature, respectively. The best separation efficiency (48.3% with 3N purity) was achieved when Si content in melt was 24% and the solid fraction was 8.7%. The melt with 23% Si led to a higher separation efficiency (69.8%) for a solid fraction of 10.4%, but Al sandwiched between the Si platelets resulted in a decrease in the purity to 2N.

  5. Influence of the permeability of networked primary Si on the ejection of hypereutectic Al-Si melts by centrifugation

    NASA Astrophysics Data System (ADS)

    Youn, Ji Won; Jeon, Je-Beom; Park, Jin Man; Seo, Seok Yong; Lim, Jeon Taik; Kim, Suk Jun; Kim, Ki Young

    2017-03-01

    The separation of high purity Si for solar cells from Al-Si alloy melt in the mushy zone was investigated using an advanced centrifugal technique. The efficiency of separating Si, based on the weight ratio of separated Si to Si in alloy melt, was maximized by optimizing the permeability of a porous structure of Si (Si foam.) For the optimization of the permeability, two fundamental microstructure variables, size and the solid fraction of primary Si platelets, were controlled by adjusting the Si content in the melts and the rotation start temperature, respectively. The best separation efficiency (48.3% with 3N purity) was achieved when Si content in melt was 24% and the solid fraction was 8.7%. The melt with 23% Si led to a higher separation efficiency (69.8%) for a solid fraction of 10.4%, but Al sandwiched between the Si platelets resulted in a decrease in the purity to 2N.

  6. Primary electric power generation systems for advanced-technology engines

    NASA Technical Reports Server (NTRS)

    Cronin, M. J.

    1983-01-01

    The advantages of the all electric airplane are discussed. In the all electric airplane the generator is the sole source of electric power; it powers the primary and secondary flight controls, the environmentals, and the landing gear. Five candidates for all electric power systems are discussed and compared. Cost benefits of the all electric airplane are discussed.

  7. An Exploratory Study on How Primary Pupils Approach Systems

    ERIC Educational Resources Information Center

    Koski, Marja-Ilona; de Vries, Marc

    2013-01-01

    This paper presents a study of systems thinking among 27 primary pupils (8-10 years old) and their teacher. The study included a pre-test for the teacher and the pupils, lesson planning, the actual lesson and a post-test for the pupils. The research focused on finding an answer to three questions: (1) do pupils see a system as a structure…

  8. [Primary central nervous system lymphoma: pathogenesis and histomorphology].

    PubMed

    Méhes, Gábor

    2017-03-08

    Lymphoproliferative diseases of the central nervous system are rare, diagnostics and treatment are accordingly challenging. Since the introduction of the 2008 WHO lymphoma classification, primary CNS DLBCL - also covering the associated primary ocular (vitreoretinal) lymphoma - is a separate entity. The special localization is related with a series of newly recognized genetic, genomic and immunologic features directing to the strong interaction between transformed lymphoma cells, neural tissue components and the local immune response. Histological differentiation is frequently disabled by the limited sampling opportunities and requires the application of all available hematopathologic technologies including immunohistochemistry, cytology, liquor serology, flow cytometry, fluorescence in situ hybridization and polymerase chain reaction with sequencing.

  9. Advanced Launch System (ALS) Space Transportation Expert System Study

    DTIC Science & Technology

    1991-03-01

    CONSIDERATIONS, CONTRACTUAL OBLIGATIONS, OR NOTICE ON A SPECIFIC DOCUMENT. DISCLAIMER NOTICE THIS DOCUMENT IS BEST QUALITY AVAILABLE. THE COPY...System Assessment Methodology 2- 11 2.3.1.1 Methodology Overview 2- 11 2.3.1.2 Approach 2- 11 2.3.1.3 Defmitions of Attributes 2- 12 2.3.2 Assessment...how the use of knowledge-based systems can help increase autonomy. A design approach to this degree of autonomy will be demonstrated in Phase 2 (ADP

  10. Improvement of the Electrochemical Behavior of Steel Surfaces Using a [Ti-Al/Ti-Al-N] n Multilayer System

    NASA Astrophysics Data System (ADS)

    Ipaz, L.; Aperador, W.; Caicedo, J. C.; Esteve, J.; Zambrano, G.

    2013-05-01

    The aim of this work is to improve the corrosion resistance of AISI D3 steel surfaces using a [Ti-Al/Ti-Al-N] n multilayer system deposited with different periods (Λ) and bilayer numbers ( n), via magnetron co-sputtering pulsed d.c. procedure, from a metallic (Ti-Al) binary target. The multilayer coatings were characterized by cross-sectional scanning electron microscopy that showed the modulation and microstructure of the [Ti-Al/Ti-Al-N] n multilayer system. The composition of the single Ti-Al and Ti-Al-N layer films was studied via x-ray photoelectron spectroscopy, where typical signals for Ti2p1/2, Ti2p, N1s, and Al2p3/2 were detected. The electrochemical properties were evaluated by electrochemical impedance spectroscopy and Tafel polarization curves. The optimal electrochemical behavior was obtained for the [Ti-Al/Ti-Al-N] n multilayered period of Λ = 25 nm (100 bilayers). At these conditions, the maximum polarization resistance (1719.32 kΩ cm2) and corrosion rate (0.7 μmy) were 300 and 35 times higher than that of uncoated AISI D3 steel substrate (5.61 kΩ cm2 and 25 μmy, respectively). Finally, scanning electron microscopy was used to analyze the [Ti-Al/Ti-Al-N] n multilayered surface after the corrosive attack. The improvement effects in the electrochemical behavior of the AISI D3 coated with the [Ti-Al/Ti-Al-N] n multilayered coatings could be attributed to the number of interfaces that act as obstacles for the inward and outward diffusions of Cl- ions, generating an increment in the energy or potential required for translating the corrosive ions across the coating/substrate interface.

  11. Targetable genetic features of primary testicular and primary central nervous system lymphomas

    PubMed Central

    Chapuy, Bjoern; Roemer, Margaretha G. M.; Stewart, Chip; Tan, Yuxiang; Abo, Ryan P.; Zhang, Liye; Dunford, Andrew J.; Meredith, David M.; Thorner, Aaron R.; Jordanova, Ekaterina S.; Liu, Gang; Feuerhake, Friedrich; Ducar, Matthew D.; Illerhaus, Gerald; Gusenleitner, Daniel; Linden, Erica A.; Sun, Heather H.; Homer, Heather; Aono, Miyuki; Pinkus, Geraldine S.; Ligon, Azra H.; Ligon, Keith L.; Ferry, Judith A.; Freeman, Gordon J.; van Hummelen, Paul; Golub, Todd R.; Getz, Gad; Rodig, Scott J.; de Jong, Daphne; Monti, Stefano

    2016-01-01

    Primary central nervous system lymphomas (PCNSLs) and primary testicular lymphomas (PTLs) are extranodal large B-cell lymphomas (LBCLs) with inferior responses to current empiric treatment regimens. To identify targetable genetic features of PCNSL and PTL, we characterized their recurrent somatic mutations, chromosomal rearrangements, copy number alterations (CNAs), and associated driver genes, and compared these comprehensive genetic signatures to those of diffuse LBCL and primary mediastinal large B-cell lymphoma (PMBL). These studies identify unique combinations of genetic alterations in discrete LBCL subtypes and subtype-selective bases for targeted therapy. PCNSLs and PTLs frequently exhibit genomic instability, and near-uniform, often biallelic, CDKN2A loss with rare TP53 mutations. PCNSLs and PTLs also use multiple genetic mechanisms to target key genes and pathways and exhibit near-uniform oncogenic Toll-like receptor signaling as a result of MYD88 mutation and/or NFKBIZ amplification, frequent concurrent B-cell receptor pathway activation, and deregulation of BCL6. Of great interest, PCNSLs and PTLs also have frequent 9p24.1/PD-L1/PD-L2 CNAs and additional translocations of these loci, structural bases of immune evasion that are shared with PMBL. PMID:26702065

  12. High-temperature phase equilibria in the Al-rich corner of the Al-Ti-C system

    SciTech Connect

    Frage, N.; Frumin, N.; Levin, L.; Polak, M.; Dariel, M.P.

    1998-04-01

    A thermodynamic analysis of the Al-rich corner in the ternary Al-Ti-C diagram, providing phase relations and regions of phase stability, is presented. An invariant four-phase equilibrium between Al, Al{sub 4}C{sub 3}, Al{sub 3}Ti, and TiC{sub x} takes place at 0.53 at. pct Ti, 7.10{sup {minus}6} at. pct C, and TiC{sub 0.883} at 966 K. The carbon content of the TiC{sub x} phase, which extends from x = 0.48 to 0.98, exerts a significant effect on phase relationships in this ternary system. In particular, it is shown that stoichiometric TiC is not stable in the presence of liquid Al. For example, at 1,300 K, a two-phase equilibrium between Al{sub L} and TiC{sub x} exists only in the 0.91 < x < 0.82 range. Thus, the interaction of Al{sub L} with stoichiometric TiC leads to the formation of the Al{sub 4}C{sub 3} aluminum carbide phase, whereas for x < 0.82, only the intermetallic compound Al{sub 3}Ti can form at this temperature. The results of this analysis were confirmed by X-ray diffraction (XRD) measurements of relevant composites.

  13. Metastability in the MgAl2O4-Al2O3 System

    DOE PAGES

    Wilkerson, Kelley R.; Smith, Jeffrey D.; Hemrick, James G.

    2014-07-22

    Aluminum oxide must take a spinel form ( γ-Al2O3) at elevated temperatures in order for extensive solid solution to form between MgAl2O4 and α-Al2O3. The solvus line between MgAl2O4 and Al2O3 has been defined at 79.6 wt% Al2O3 at 1500°C, 83.0 wt% Al2O3 at 1600°C, and 86.5 wt% Al2O3 at 1700°C. A metastable region has been defined at temperatures up to 1700°C which could have significant implications for material processing and properties. Additionally, initial processing could have major implications on final chemistry. The spinel solid solution region has been extended to form an infinite solid solution with Al2O3 at elevatedmore » temperatures. A minimum in melting at 1975°C and a chemistry of 96 wt% Al2O3 rather than a eutectic is present, resulting in no eutectic crystal formation during solidification.« less

  14. A primary mirror metrology system for the GMT

    NASA Astrophysics Data System (ADS)

    Rakich, A.

    2016-07-01

    The Giant Magellan Telescope (GMT)1 is a 25 m "doubly segmented" telescope composed of seven 8.4 m "unit Gregorian telescopes", on a common mount. Each primary and secondary mirror segment will ideally lie on the geometrical surface of the corresponding rotationally symmetrical full aperture optical element. Therefore, each primary and conjugated secondary mirror segment will feed a common instrument interface, their focal planes co-aligned and cophased. First light with a subset of four unit telescopes is currently scheduled for 2022. The project is currently considering an important aspect of the assembly, integration and verification (AIV) phase of the project. This paper will discuss a dedicated system to directly characterize the on-sky performance of the M1 segments, independently of the M2 subsystem. A Primary Mirror Metrology System (PMS) is proposed. The main purpose of this system will be to he4lp determine the rotation axis of an instrument rotator (the Gregorian Instrument Rotator or GIR in this case) and then to characterize the deflections and deformations of the M1 segments with respect to this axis as a function of gravity and temperature. The metrology system will incorporate a small (180 mm diameter largest element) prime focus corrector (PFC) that simultaneously feeds a <60" square acquisition and guiding camera field, and a Shack Hartmann wavefront sensor. The PMS is seen as a significant factor in risk reduction during AIV; it allows an on-sky characterization of the primary mirror segments and cells, without the complications of other optical elements. The PMS enables a very useful alignment strategy that constrains each primary mirror segments' optical axes to follow the GIR axis to within a few arc seconds. An additional attractive feature of the incorporation of the PMS into the AIV plan, is that it allows first on-sky telescope operations to occur with a system of considerably less optical and control complexity than the final doubly

  15. Advising potential recipients on the use of organs from donors with primary central nervous system tumors.

    PubMed

    Warrens, Anthony N; Birch, Rhiannon; Collett, David; Daraktchiev, Maren; Dark, John H; Galea, George; Gronow, Katie; Neuberger, James; Hilton, David; Whittle, Ian R; Watson, Christopher J E

    2012-02-27

    Deciding to use an organ from a donor with a primary central nervous system (CNS) tumor necessitates offsetting the risk of tumor transmission with the chances of survival if the patient waits for another offer of a transplant. Published data vary in the quoted risk of tumor transmission. We used data obtained by reviewing 246 UK recipients of organs taken from donors with CNS tumors and found no evidence of a difference in overall patient mortality for recipients of a kidney, liver, or cardiothoracic organ, compared with recipients of organs from donors without a CNS tumor. Recent publication of the UK experience of transplanting organs from CNS tumor donors found no transmission in 448 recipients of organs from 177 donors with a primary CNS tumor (Watson et al., Am J Transplant 2010; 10: 1437). This 0% transmission rate is associated with an upper 95% confidence interval limit of 1.5%. Using a series of assumptions of risk, we compared the risks of dying as a result of the transmission of a primary brain tumor with the risks of dying if not transplanted. On this basis, the use of kidneys from a donor with a primary CNS tumor provides a further 8 years of life over someone who waited for a donor who did not have a primary CNS tumor, in addition to the life years gained by the transplant itself. The benefits for the recipients of livers and cardiothoracic organs were less, but there was no disadvantage in the impact on life expectancy.

  16. Effect of Shrinkage on Primary Dendrite Arm Spacing during Binary Al-Si Alloy Solidification

    NASA Astrophysics Data System (ADS)

    Wang, Hongda; Hamed, Mohamed S.; Shankar, Sumanth

    2011-08-01

    Upward and downward directional solidification of hypoeutectic Al-Si alloys were numerically simulated inside a cylindrical container. Undercooling of the liquidus temperature prior to the solidification event was introduced in the numerical model. The finite-volume method was used to solve the energy, concentration, momentum, and continuity equations. Temperature and liquid concentrations inside the mushy zone were coupled with local equilibrium assumptions. An energy equation was applied to determine the liquid fraction inside the mushy zone while considering the temperature undercooling at the solidifying dendrite/liquid interface. Momentum and continuity equations were coupled by the SIMPLE algorithm. Flow velocity distribution at various times, G, R, λ 1, and solidification time at mushy zone/liquid interface during solidification were predicted. The effect of shrinkage during solidification on these solidification parameters was quantified. Transient temperature distribution, solidification time for the mushy zone/liquid interface, and λ 1 were validated by laboratory experiments. It was found that better agreement could be achieved when the fluid flow due to solidification shrinkage was considered. Considering shrinkage in upward solidification was found to only have a marginal effect on solidification parameters, such as G, R, and λ 1; whereas, in the downward solidification, fluid flow due to shrinkage had a significant effect on these solidification parameters. Considering shrinkage during downward solidification resulted in a smaller R, stronger fluid flow, and increased solidification time at the mushy zone/liquid interface. Further, the flow pattern was significantly altered when solidification shrinkage was considered in the simulation. The effect of shrinkage on G and λ 1 strongly depended on the instantaneous location of the mushy zone/liquid interface in the computational domain. The numerical results could be validated by experimental data

  17. Behavior modification in primary care: the pressure system model.

    PubMed

    Katz, D L

    2001-01-01

    The leading causes of death in the United States are predominantly attributable to modifiable behaviors. Patients with behavioral risk factors for premature death and disability, including dietary practices; sexual practices; level of physical activity; motor vehi cle use patterns; and tobacco, alcohol, and illicit sub stance use, are seen far more consistently by primary care providers than by mental health specialists. Yet models of behavior modification are reported, debated, and revised almost exclusively in the psychology literature. While the Stages of Change Model, or Transtheo retical Model, has won application in a broadening array of clinical settings, its application in the primary care setting is apparently quite limited despite evidence of its utility [Prochaska J, Velicer W. Am J Health Promot 1997;12:38-48]. The lack of a rigorous behavioral model developed for application in the primary care setting is an impediment to the accomplishment of public health goals specified in the Healthy People objectives and in the reports of the U.S. Preventive Services Task Force. The Pressure System Model reported here synthesizes elements of established behavior modification theories for specific application under the constraints of the primary care setting. Use of the model in both clinical and research settings, with outcome evaluation, is encouraged as part of an effort to advance public health.

  18. Preoperational test report, primary ventilation condenser cooling system

    SciTech Connect

    Clifton, F.T.

    1997-10-29

    This represents the preoperational test report for the Primary Ventilation Condenser Cooling System, Project W-030. Project W-030 provides a ventilation upgrade for the four Aging Waste Facility tanks. The system uses a closed chilled water piping loop to provide offgas effluent cooling for tanks AY101, AY102, AZ1O1, AZ102; the offgas is cooled from a nominal 100 F to 40 F. Resulting condensation removes tritiated vapor from the exhaust stack stream. The piping system includes a package outdoor air-cooled water chiller with parallel redundant circulating pumps; the condenser coil is located inside a shielded ventilation equipment cell. The tests verify correct system operation and correct indications displayed by the central Monitor and Control System.

  19. RELAP5 MODEL OF THE DIVERTOR PRIMARY HEAT TRANSFER SYSTEM

    SciTech Connect

    Popov, Emilian L; Yoder Jr, Graydon L; Kim, Seokho H

    2010-08-01

    This report describes the RELAP5 model that has been developed for the divertor primary heat transfer system (PHTS). The model is intended to be used to examine the transient performance of the divertor PHTS and evaluate control schemes necessary to maintain parameters within acceptable limits during transients. Some preliminary results are presented to show the maturity of the model and examine general divertor PHTS transient behavior. The model can be used as a starting point for developing transient modeling capability, including control system modeling, safety evaluations, etc., and is not intended to represent the final divertor PHTS design. Preliminary calculations using the models indicate that during normal pulsed operation, present pressurizer controls may not be sufficient to keep system pressures within their desired range. Additional divertor PHTS and control system design efforts may be required to ensure system pressure fluctuation during normal operation remains within specified limits.

  20. Apollo experience report guidance and control systems: Primary guidance, navigation, and control system development

    NASA Technical Reports Server (NTRS)

    Holley, M. D.; Swingle, W. L.; Bachman, S. L.; Leblanc, C. J.; Howard, H. T.; Biggs, H. M.

    1976-01-01

    The primary guidance, navigation, and control systems for both the lunar module and the command module are described. Development of the Apollo primary guidance systems is traced from adaptation of the Polaris Mark II system through evolution from Block I to Block II configurations; the discussion includes design concepts used, test and qualification programs performed, and major problems encountered. The major subsystems (inertial, computer, and optical) are covered. Separate sections on the inertial components (gyroscopes and accelerometers) are presented because these components represent a major contribution to the success of the primary guidance, navigation, and control system.

  1. Long-period ordered superstructures that appear in an (Al,Ga)-rich (Al,Ga)Ti system

    NASA Astrophysics Data System (ADS)

    Nakano, Takayoshi; Hagihara, Koji; Hata, Satoshi; Shigyo, Hajime; Nakashima, Hideharu; Umakoshi, Yukichi; Arya, Ashok; Kulkarni, Ulhas D.

    2013-01-01

    Long-period ordered superstructures in an (Al,Ga)-rich (Al,Ga)Ti system composed of (Al,Ga) x Ti100- x (x = 50-65 at. %) were investigated by using melt-spun ribbons, focusing on the ordering process of the superstructural phases. Compositional regions in which h-(Al,Ga)2Ti (Ga2Zr-type), (Al,Ga)5Ti3 and (Al,Ga)3Ti2 with threefold, fourfold and fivefold periodicity, respectively, appeared coherently in the L10 matrix were identified by electron diffraction patterns in two different temperature conditions of as-spun (a relatively high-temperature state) and heat-treatment at 700°C (a relatively low-temperature state). The (Al,Ga)5Ti3 superstructural phase always existed between the compositional region where h-(Al,Ga)2Ti and (Al,Ga)3Ti2 dominantly appear. Therefore, periodical ordering proceeds following the periodicity of the concentration wave of pure (Al,Ga) layers parallel to {310) in the Ti (002) layers from threefold to fivefold periodicity via fourfold periodicity. We found that the (Al,Ga)3Ti2 long-period superstructural phase preferentially appeared with increasing Ga concentration in the melt-spun ribbon annealed at 700°C. In other words, the h-(Al,Ga)2Ti superstructure with threefold periodicity preferentially appeared at the high temperature and a low Ga concentration. Thus, the (Al,Ga)3Ti2-type superstructure was never produced without the addition of Ga in the present study. The long-period ordered superstructures were composed of three pairs of primitive cells, (Al,Ga)Ti2, (Al,Ga)Ti3 and (Al,Ga)Ti4, with periodic atomic arrangements corresponding to lean rhombus, fat rhombus and square, respectively. We discuss the ordering process throughout the (Al,Ga)5 ? superstructure based on the periodic concentration wave and exchange of atoms. The effect of long-period ordered superstructures on hardness is also mentioned.

  2. Use of Fuzzy Logic Systems for Assessment of Primary Faults

    NASA Astrophysics Data System (ADS)

    Petrović, Ivica; Jozsa, Lajos; Baus, Zoran

    2015-09-01

    In electric power systems, grid elements are often subjected to very complex and demanding disturbances or dangerous operating conditions. Determining initial fault or cause of those states is a difficult task. When fault occurs, often it is an imperative to disconnect affected grid element from the grid. This paper contains an overview of possibilities for using fuzzy logic in an assessment of primary faults in the transmission grid. The tool for this task is SCADA system, which is based on information of currents, voltages, events of protection devices and status of circuit breakers in the grid. The function model described with the membership function and fuzzy logic systems will be presented in the paper. For input data, diagnostics system uses information of protection devices tripping, states of circuit breakers and measurements of currents and voltages before and after faults.

  3. Measured Activities of Al and Ni in gamma-(Ni) and gamma'-(Ni)3Al in the Ni-Al-Pt System

    NASA Technical Reports Server (NTRS)

    Copland, Evan

    2007-01-01

    Adding Pt to Ni-Al coatings is critical to achieving the required oxidation protection of Ni-based superalloys, but the nature of the Pt effect remains unresolved. This research provides a fundamental part of the answer by measuring the influence of Pt on the activities of Al and Ni in gamma-(Ni), gamma prime-(Ni)3Al and liquid in the Ni-Al-Pt system. Measurements have been made at 25 compositions in the Ni-rich corner over the temperature range, T = 1400-1750 K, by the vapor pressure technique with a multiple effusion-cell mass spectrometer (multi-cell KEMS). These measurements clearly show adding Pt (for X(sub Pt) less than 0.25) decreases a(Al) while increasing a(Ni). This solution behavior supports the idea that Pt increases Al transport to an alloy / Al2O3 interface and also limits the interaction between the coating and substrate alloys in the gamma-(Ni) + gamma prime-(Ni)3Al region. This presentation will review the progress of this study.

  4. Cryptanalysis and improvement of Yan et al.'s biometric-based authentication scheme for telecare medicine information systems.

    PubMed

    Mishra, Dheerendra; Mukhopadhyay, Sourav; Chaturvedi, Ankita; Kumari, Saru; Khan, Muhammad Khurram

    2014-06-01

    Remote user authentication is desirable for a Telecare Medicine Information System (TMIS) for the safety, security and integrity of transmitted data over the public channel. In 2013, Tan presented a biometric based remote user authentication scheme and claimed that his scheme is secure. Recently, Yan et al. demonstrated some drawbacks in Tan's scheme and proposed an improved scheme to erase the drawbacks of Tan's scheme. We analyze Yan et al.'s scheme and identify that their scheme is vulnerable to off-line password guessing attack, and does not protect anonymity. Moreover, in their scheme, login and password change phases are inefficient to identify the correctness of input where inefficiency in password change phase can cause denial of service attack. Further, we design an improved scheme for TMIS with the aim to eliminate the drawbacks of Yan et al.'s scheme.

  5. Development of a primary angular shock calibration system

    NASA Astrophysics Data System (ADS)

    Peng, Jun

    2008-06-01

    Primary angular shock calibration system is developed by Changcheng Institute of Metrology & Measurement (CIMM). It uses brushless servo motor driving the air bearing system to generate rotational angle, angular velocity and angular acceleration. Both grating and heterodyne laser interferometer with diffraction grating is used to measure the angular movement, which are traceable to the International System of Units (SI). It can be used to calibrate angular transducers, i.e. angular accelerometer, angular velocity transducer, and rotational angle transducer to obtain sensitivity by angular shock or other kinds of excitation. Heterodyne laser interferometer with diffraction grating is successfully used in the measurement of angular acceleration. The method of using grating and scanning heads measure angular acceleration is developed. One characteristic of this system is that it could generate different kind of excitation signals, which include half sine, trapezoidal, sinusoidal, etc. and it can work as a high performance rate table to generate constant angular velocity. The preliminary test shows the uncertainty in calibrating angular accelerometer should be better than 2%. This paper introduces the mechanic system, control system and measurement system of the angular shock calibration system.

  6. Composition and solidification microstructure selection in the interdendritic matrix between primary Al{sub 3}Fe dendrites in hypereutectic Al-Fe alloys

    SciTech Connect

    Liang, D.; Korgul, P.; Jones, H.

    1996-07-01

    The composition and constitution of matrix microstructure between plate-like Al{sub 3}Fe dendrites in Bridgman-grown hypereutectic Al-Fe alloys has been determined as a function of alloy concentration C{sub 0} and growth velocity V in the ranges 2.5 < C{sub 0} < 28.1 wt%Fe and 0.01 < V < 5.0 mm/s. The transition at V = 0.1 mm/s from a fully eutectic matrix at C{sub 0} = 3.5 wt%Fe to one containing {alpha}Al dendrites at C{sub 0} {ge} 4.7 wt%Fe is attributed to growth temperatures of {alpha}Al dendrites that are higher than those of eutectic in a matrix of lower iron-content, which results from these conditions. The matrix eutectic changes from irregular {alpha}-Al-Al{sub 3}Fe to regular {alpha}Al-Al{sub x}Fe with increasing V, the transition velocity increasing from 0.1 to 0.2 mm/s for C{sub 0} values of 9.5 and 14 wt%Fe up to 0.35--1.0 mm/s for C{sub 0} values of 18.7--28.1 wt%Fe. This increased transition velocity, compared with that for {alpha}-Al-Al{sub 3}Fe to {alpha}Al-Al{sub 6}Fe at lower concentration, is indicative of a lower formation temperature for the {alpha}Al-Al{sub x}Fe than the {alpha}Al-Al{sub 6}Fe eutectic.

  7. EVALUATION OF THE TEMPORARY TENT COVER TRUSS SYSTEM AP PRIMARY VENT SYSTEM

    SciTech Connect

    HAQ MA

    2009-12-31

    The purpose of this calculation is to evaluate a temporary ten cover truss system. This system will be used to provide weather protection to the workers during replacement of the filter for the Primary Ventilation System in AP Tank Farm. The truss system has been fabricated utilizing tubes and couplers, which are normally used for scaffoldings.

  8. Development of an allergy management support system in primary care

    PubMed Central

    Flokstra - de Blok, Bertine MJ; van der Molen, Thys; Christoffers, Wianda A; Kocks, Janwillem WH; Oei, Richard L; Oude Elberink, Joanne NG; Roerdink, Emmy M; Schuttelaar, Marie Louise; van der Velde, Jantina L; Brakel, Thecla M; Dubois, Anthony EJ

    2017-01-01

    Background Management of allergic patients in the population is becoming more difficult because of increases in both complexity and prevalence. Although general practitioners (GPs) are expected to play an important role in the care of allergic patients, they often feel ill-equipped for this task. Therefore, the aim of this study was to develop an allergy management support system (AMSS) for primary care. Methods Through literature review, interviewing and testing in secondary and primary care patients, an allergy history questionnaire was constructed by allergists, dermatologists, GPs and researchers based on primary care and specialists’ allergy guidelines and their clinical knowledge. Patterns of AMSS questionnaire responses and specific immunoglobulin E (sIgE)-test outcomes were used to identify diagnostic categories and develop corresponding management recommendations. Validity of the AMSS was investigated by comparing specialist (gold standard) and AMSS diagnostic categories. Results The two-page patient-completed AMSS questionnaire consists of 12 (mainly) multiple choice questions on symptoms, triggers, severity and medication. Based on the AMSS questionnaires and sIgE-test outcome of 118 patients, approximately 150 diagnostic categories of allergic rhinitis, asthma, atopic dermatitis, anaphylaxis, food allergy, hymenoptera allergy and other allergies were identified, and the corresponding management recommendations were formulated. The agreement between the allergy specialists’ assessments and the AMSS was 69.2% (CI 67.2–71.2). Conclusion Using a systematic approach, it was possible to develop an AMSS that allows for the formulation of diagnostic and management recommendations for GPs managing allergic patients. The AMSS thus holds promise for the improvement of the quality of primary care for this increasing group of patients. PMID:28352197

  9. Combustion synthesis of ceramic-metal composite materials - The TiC-Al2O3-Al system

    NASA Technical Reports Server (NTRS)

    Feng, H. J.; Moore, John J.; Wirth, D. G.

    1992-01-01

    Combustion synthesis was applied for producing ceramic-metal composites with reduced levels of porosity, by allowing an excess amount of liquid metal, generated by the exothermic reaction during synthesis, to infiltrate the pores. It is shown that this method, when applied to TiC-Al2O3 system, led to a decreased level of porosity in the resulting TiC-Al2O3-Al product, as compared with that of TiC-Al2O3 system. This in situ procedure is more efficient than the two-stage conventional processes (i.e., sintering followed by liquid metal infiltration), although there are limitations with respect to total penetration of the liquid metal and maintaining a stable propagation of the combustion reaction.

  10. Shortening the Time of Heat Treatment of Silumins of the Al - Si - Cu System by Modifying their Structure

    NASA Astrophysics Data System (ADS)

    Nikitin, K. V.; Chikova, O. A.; Amosov, E. A.; Nikitin, V. I.

    2016-11-01

    The possibility of shortening the heat treatment hold of silumins of the Al - Si - Cu system by changing the parameters of the structure under chill casting is considered and a criterion for their evaluation is suggested. Alloys AK6M2 and AK8M3ch are used to demonstrate experimentally that decrease in the sizes of the crystals of primary silicon and in the transverse size of the α-Al secondary dendrite arms can halve the time of holding for quenching and aging at a guaranteed margin of the strength properties.

  11. Primary propulsion/large space system interaction study

    NASA Technical Reports Server (NTRS)

    Coyner, J. V.; Dergance, R. H.; Robertson, R. I.; Wiggins, J. V.

    1981-01-01

    An interaction study was conducted between propulsion systems and large space structures to determine the effect of low thrust primary propulsion system characteristics on the mass, area, and orbit transfer characteristics of large space systems (LSS). The LSS which were considered would be deployed from the space shuttle orbiter bay in low Earth orbit, then transferred to geosynchronous equatorial orbit by their own propulsion systems. The types of structures studied were the expandable box truss, hoop and column, and wrap radial rib each with various surface mesh densities. The impact of the acceleration forces on system sizing was determined and the effects of single point, multipoint, and transient thrust applications were examined. Orbit transfer strategies were analyzed to determine the required velocity increment, burn time, trip time, and payload capability over a range of final acceleration levels. Variables considered were number of perigee burns, delivered specific impulse, and constant thrust and constant acceleration modes of propulsion. Propulsion stages were sized for four propellant combinations; oxygen/hydrogen, oxygen/methane, oxygen/kerosene, and nitrogen tetroxide/monomethylhydrazine, for pump fed and pressure fed engine systems. Two types of tankage configurations were evaluated, minimum length to maximize available payload volume and maximum performance to maximize available payload mass.

  12. An evaluation of four telemedicine systems for primary care.

    PubMed Central

    Dunn, E V; Conrath, D W; Bloor, W G; Tranquada, B

    1977-01-01

    In an evaluation of the efficacy of four two-way telecommunication systems for use in primary care, more than 1,000 patients seeking care at a community health center received an additional remote examination by use of either color television, black and white television, still-frame black and white television, or hands-free telephone. The diagnosis, clinical tests and X rays requested, and proposed patient management were compared to the actual care received by the patients at the health center. There were no significant differences between any of the modes in relation to diagnostic accuracy, time for the diagnostic interview, tests requested, or referral rates. Furthermore, patient attitudes did not vary significantly. Thus the relatively inexpensive telephone proved to be as efficient and effective a means for delivery of remote physician care as did any of the visual communication systems. PMID:873812

  13. Fission Product Migration in Primary System and Containment

    SciTech Connect

    2015-04-01

    Version 00 ART MOD2 aims at a comprehensive analysis for the FP behaviour in primary system and in containment during severe accidents and therefore the code considers the removal of radio-nuclides of up to 60 materials including chemical compounds by natural deposition and by the engineered safety features (ESF) such as spray systems. As for the natural deposition of radio-nuclides, the code can consider the phenomena such as gravitational settling, thermophoresis, diffusiophoresis, Brownian diffusion, diffusion under laminar or turbulent flows, resuspension, condensation, chemisorption and revaporization. The code also models the aerosol growth by agglomeration of aerosols and condensation/evaporation of volatile material at the aerosol surface. Recently, the models for iodine chemistry in containment sump water was incorporated into ART MOD2 ART MOD2 was modified in January 2015 to correct coding errors and improve the vibration of the calculation result of water (H2O) vapor.

  14. Optimized Battery-Type Reactor Primary System Design Utilizing Lead

    SciTech Connect

    Yu, Yong H.; Son, Hyoung M.; Lee, Il S.; Suh, Kune Y.

    2006-07-01

    A number of small and medium size reactors are being developed worldwide as well as large electricity generation reactors for co-generation, district heating or desalination. The Seoul National University has started to develop 23 MWth BORIS (Battery Optimized Reactor Integral System) as a multi-purpose reactor. BORIS is an integral-type optimized fast reactor with an ultra long life core. BORIS is being designed to meet the Generation IV nuclear energy system goals of sustainability, safety, reliability and economics. Major features of BORIS include 20 consecutive years of operation without refueling; elimination of an intermediate heat transport loop and main coolant pump; open core without individual subassemblies; inherent negative reactivity feedback; and inherent load following capability. Its one mission is to provide incremental electricity generation to match the needs of developing nations and especially remote communities without major electrical grid connections. BORIS consists of a reactor module, heat exchanger, coolant module, guard vessel, reactor vessel auxiliary cooling system (RVACS), secondary system, containment and the seismic isolation. BORIS is designed to generate 10 MWe with the resulting thermal efficiency of 45 %. BORIS uses lead as the primary system coolant because of the inherent safety of the material. BORIS is coupled with a supercritical carbon dioxide Brayton cycle as the secondary system to gain a high cycle efficiency in the range of 45 %. The reference core consists of 757 fuel rods without assembly with an active core height of 0.8 m. The BORIS core consists of single enrichment zone composed of a Pu-MA (minor actinides)-U-N fuel and a ferritic-martensitic stainless steel clad. This study is intended to set up appropriate reactor vessel geometry by performing thermal hydraulic analysis on RVACS using computational fluid dynamics codes; to examine the liquid metal coolant behavior along the subchannels; to find out whether the

  15. NiAl-based Polyphase in situ Composites in the NiAl-Ta-X (X = Cr, Mo, or V) Systems

    NASA Technical Reports Server (NTRS)

    Johnson, D. R.; Oliver, B. F.; Noebe, R. D.; Whittenberger, J. D.

    1995-01-01

    Polyphase in situ composites were generated by directional solidification of ternary eutectics. This work was performed to discover if a balance of properties could be produced by combining the NiAl-Laves phase and the NiAl-refractory metal phase eutectics. The systems investigated were the Ni-Al-Ta-X (X = Cr, Mo, or V) alloys. Ternary eutectics were found in each of these systems and the eutectic composition, temperature, and morphology were determined. The ternary eutectic systems examined were the NiAl-NiAlTa-(Mo, Ta), NiAl-(Cr, Al) NiTa-Cr, and the NiAl-NiAlTa-V systems. Each eutectic consists of NiAl, a C14 Laves phase, and a refractory metal phase. Directional solidification was performed by containerless processing techniques in a levitation zone refiner to minimize alloy contamination. Room temperature fracture toughness of these materials was determined by a four-point bend test. Preliminary creep behavior was determined by compression tests at elevated temperatures, 1100-l400 K. Of the ternary eutectics, the one in the NiAl-Ta-Cr system was found to be the most promising. The fracture toughness of the NiAl-(Cr, Al)NiTa-Cr eutectic was intermediate between the values of the NiAl-NiAlTa eutectic and the NiAl-Cr eutectic. The creep strength of this ternary eutectic was similar to or greater than that of the NiAl-Cr eutectic.

  16. Compact TPV Generation System Using Al2O3/Er3Al5O12 Eutectic Ceramics Selective Emitters

    NASA Astrophysics Data System (ADS)

    Adachi, Yusuke; Yugami, Hiroo; Shibata, Kouji; Nakagawa, Narihito

    2004-11-01

    The emissive properties of Al2O3Er3Al5O12 eutectic ceramics have been measured as a candidate of selective emitters. It is identified that the Al2O3Er3Al5O12 eutectic ceramics have selective emission bands at the wavelength of 1.5 μm, and the emittance at the emission peak is over 0.8. The selective emissive power for GaSb photovoltaic (PV) cells of 49 kW/m2 is achieved by this material at 1600 K. Since the emission bands match the sensitive region of GaSb PV cells, the Al2O3Er3Al5O12 eutectic ceramics are suited as emitter materials in thermophotovoltaic (TPV) systems using GaSb PV cells. The optical design of small-scale TPV systems for portable power sources has been investigated with the three-dimensional ray tracing simulation. Using a mirror/PV optical design, the concentrated thermal radiation is irradiated on PV cells with the view factor over 0.75.

  17. Interdiffusion and Intrinsic Diffusion in the Mg-Al System

    SciTech Connect

    Brennan, Sarah; Bermudez, Katrina; Sohn, Yong Ho; Kulkarni, Nagraj S

    2012-01-01

    Solid-to-solid diffusion couples were assembled and annealed to examine the diffusion between pure Mg (99.96%) and Al (99.999%). Diffusion anneals were carried out at 300 , 350 , and 400 C for 720, 360, and 240 hours, respectively. Optical and scanning electron microscopes were utilized to identify the formation of the intermetallic phases, -Al12Mg17 and -Al3Mg2 and absence of the -phase in the diffusion couples. Thicknesses of the -Al12Mg17 and -Al3Mg2 phases were measured and the parabolic growth constants were calculated to determine the activation energies for the growth, 165 and 86 KJ/mole, respectively. Concentration profiles were determined with electron microprobe analysis using pure elemental standards. Composition-dependent interdiffusion coefficients in Mg-solid solution, -Al12Mg17 and - Al3Mg2 and Al-solid solutions were calculated based on the Boltzmann-Matano analysis. Average effective interdiffusion coefficients for each phase were also calculated, and the magnitude was the highest for the -Al3Mg2 phase, followed by -Al12Mg17, Al-solid solution and Mg-solid solution. Intrinsic diffusion coefficients based on Huemann s analysis (e.g., marker plane) were determined for the ~38 at.% Mg in the -Al3Mg2 phase. Activation energies and the pre-exponential factors for the inter- and intrinsic diffusion coefficients were calculated for the temperature range examined. The -Al3Mg2 phase was found to have the lowest activation energies for growth and interdiffusion among all four phases studied. At the marker location in the -Al3Mg2 phase, the intrinsic diffusion of Al was found to be faster than that of Mg. Extrapolations of the impurity diffusion coefficients in the terminal solid solutions were made and compared to the available self- and impurity diffusion data from literature. Thermodynamic factor, tracer diffusion coefficients and atomic mobilities at the marker plane composition were approximated using available literature values of Mg activity in the -Al

  18. A Study of Diffusivity in the BCC Solid Solution of Nb-Al and Nb-Ti-Al System

    DTIC Science & Technology

    1990-01-01

    A STUDY OF DIFFUSIVITY IN THE BCC SOLID SOLUTION OF Nb-Al AND Nb-Ti-Al SYSTEM P DTIC ELECTE NOV 3o01993 A- J.BY JOSE GUADALUPE LUIS RUIZ APARICIO A...analysis was employed for the evaluation of composition profiles in all the diffusion couples. Tne interdiffusion coefficient for the 0 solid solution of Nb...system suggest that Ti is the fastest element in the J0 solid solution . Qualitatively the penetration tendencies correlate with the melting point of

  19. 49 CFR 214.529 - In-service failure of primary braking system.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 4 2013-10-01 2013-10-01 false In-service failure of primary braking system. 214... Maintenance Machines and Hi-Rail Vehicles § 214.529 In-service failure of primary braking system. (a) In the event of a total in-service failure of its primary braking system, an on-track roadway...

  20. 49 CFR 214.529 - In-service failure of primary braking system.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 4 2012-10-01 2012-10-01 false In-service failure of primary braking system. 214... Maintenance Machines and Hi-Rail Vehicles § 214.529 In-service failure of primary braking system. (a) In the event of a total in-service failure of its primary braking system, an on-track roadway...

  1. 49 CFR 214.529 - In-service failure of primary braking system.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 4 2014-10-01 2014-10-01 false In-service failure of primary braking system. 214... Maintenance Machines and Hi-Rail Vehicles § 214.529 In-service failure of primary braking system. (a) In the event of a total in-service failure of its primary braking system, an on-track roadway...

  2. 49 CFR 214.529 - In-service failure of primary braking system.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false In-service failure of primary braking system. 214... Maintenance Machines and Hi-Rail Vehicles § 214.529 In-service failure of primary braking system. (a) In the event of a total in-service failure of its primary braking system, an on-track roadway...

  3. 49 CFR 214.529 - In-service failure of primary braking system.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 4 2011-10-01 2011-10-01 false In-service failure of primary braking system. 214... Maintenance Machines and Hi-Rail Vehicles § 214.529 In-service failure of primary braking system. (a) In the event of a total in-service failure of its primary braking system, an on-track roadway...

  4. Neuropsychological profile of patients with primary systemic hypertension.

    PubMed

    Ostrosky-Solis, F; Mendoza, V U; Ardila, A

    2001-01-01

    Arterial hypertension represents a risk factor for cerebrovascular disease. It has been hypothesized that chronic hypertension may eventually result in small subcortical infarcts associated with some cognitive impairments. One hundred fourteen patients with primary systemic hypertension (PSH) and 114 matched subjects were selected. PSH patients were further divided in four groups depending upon the hypertension severity. In addition to the medical and laboratory exams, a neuropsychological evaluation was administered. The NEUROPSI neuropsychological test battery was used. An association between level of hypertension and cognitive impairment was observed. Most significant differences were observed in the following domains: Reading, executive functioning, constructional, and memory-recall. No differences were observed in orientation, memory-recognition, and language. Some neuropsychological functions appeared impaired even in the PSH group with the least risk factors. Cognitive evaluation may be important in cases of PSH not only to determine early subtle cognitive changes, but also for follow-up purposes, and to assess the efficacy of different therapeutic procedures.

  5. Primary large-cell lymphoma of the central nervous system

    SciTech Connect

    Amendola, B.E.; McClatchey, K.D.; Amendola, M.A.; Gebarski, S.S.

    1986-06-01

    Primary non-Hodgkin's lymphoma of the central nervous system (CNS) is a rare disease. Seven patients were seen and treated at the University of Michigan Medical Center between January 1969 and December 1983. All patients had histologically proven diagnoses of large cell lymphoma with clinical and radiologic evidence of involvement limited to the CNS. Five of seven patients received postoperative radiation therapy, two of whom have had apparent local control at 1- and 2-year follow-up. The two patients without postoperative radiation died of local recurrence 2 and 3 months following subtotal resection. These poor results suggest that adjuvant therapy may be required for improved control of this type of extranodal lymphoma.

  6. Shuttle primary reaction control system engine exhaust plume contamination effects

    NASA Technical Reports Server (NTRS)

    Koontz, Steve; Ehlers, Horst; Pedley, Mike; Cross, John; Hakes, Charles

    1993-01-01

    Space Shuttle proximity operations constitute an important part of the SSF induced external environment. The impingement of primary reaction control system (PRCS) engine plumes on SSF functional surfaces during docking or berthing and separation leads to concerns about molecular contamination and high speed particle impact. The Shuttle Plume Impingement flight Experiment (SPIE) was designed to provide a direct measure of both the molecular contamination and particle impact rates produced by Shuttle PRCS engines in the LEO environment. The measured permanent deposition produced by PRCS engine firings was less than that assumed in current SSF programatic assessments. Only two to three possible high velocity particle impact pits were observed on the RMS end effector hardware.

  7. Primary Standards Laboratory report

    SciTech Connect

    Not Available

    1990-12-01

    Sandia National Laboratories operates the Primary Standards Laboratory (PSL) for the Department of Energy, Albuquerque Operations Office (DOE/AL). This report summarizes metrology activities that received emphasis in the first half of 1990 and provides information pertinent to the operation of the DOE/AL system-wide Standards and Calibration Program.

  8. Chemotherapy in newly diagnosed primary central nervous system lymphoma

    PubMed Central

    Hashemi-Sadraei, Nooshin; Peereboom, David M.

    2010-01-01

    Primary central nervous system lymphoma (PCNSL) accounts for only 3% of brain tumors. It can involve the brain parenchyma, leptomeninges, eyes and the spinal cord. Unlike systemic lymphoma, durable remissions remain uncommon. Although phase III trials in this rare disease are difficult to perform, many phase II trials have attempted to define standards of care. Treatment modalities for patients with newly diagnosed PCNSL include radiation and/or chemotherapy. While the role of radiation therapy for initial management of PCNSL is controversial, clinical trials will attempt to improve the therapeutic index of this modality. Routes of chemotherapy administration include intravenous, intraocular, intraventricular or intra-arterial. Multiple trials have outlined different methotrexate-based chemotherapy regimens and have used local techniques to improve drug delivery. A major challenge in the management of patients with PCNSL remains the delivery of aggressive treatment with preservation of neurocognitive function. Because PCNSL is rare, it is important to perform multicenter clinical trials and to incorporate detailed measurements of long-term toxicities. In this review we focus on different chemotherapeutic approaches for immunocompetent patients with newly diagnosed PCNSL and discuss the role of local drug delivery in addition to systemic therapy. We also address the neurocognitive toxicity of treatment. PMID:21789140

  9. The Australian experiment: how primary health care organizations supported the evolution of a primary health care system.

    PubMed

    Nicholson, Caroline; Jackson, Claire L; Marley, John E; Wells, Robert

    2012-03-01

    Primary health care in Australia has undergone 2 decades of change. Starting with a vision for a national health strategy with general practice at its core, Australia established local meso-level primary health care organizations--Divisions of General Practice--moving from focus on individual practitioners to a professional collective local voice. The article identifies how these meso-level organizations have helped the Australian primary health care system evolve by supporting the roll-out of initiatives including national practice accreditation, a focus on quality improvement, expansion of multidisciplinary teams into general practice, regional integration, information technology adoption, and improved access to care. Nevertheless, there are still challenges to ensuring equitable access and the supply and distribution of a primary care workforce, addressing the increasing rates of chronic disease and obesity, and overcoming the fragmentation of funding and accountability in the Australian system.

  10. Primary Central Nervous System Anaplastic Large T-cell Lymphoma

    PubMed Central

    Splavski, Bruno; Muzevic, Dario; Ladenhauser-Palijan, Tatjana; Jr, Brano Splavski

    2016-01-01

    Introduction: Primary central nervous system lymphoma (PCNSL) of T-cell origin is an exceptionally rare, highly malignant intracranial neoplasm. Although such a tumor typically presents with a focal mass lesion. Case report: Past medical history of a 26-year-old male patient with a PCNS lymphoma of T-cell origin was not suggestive of intracranial pathology or any disorder of other organs and organic systems. To achieve a gross total tumor resection, surgery was performed via osteoplastic craniotomy using the left frontal transcortical transventricular approach. Histological and immunohistochemical analyses of the tissue removed described tumor as anaplastic large cell lymphoma of T-cells (T-ALCL). Postoperative and neurological recovery was complete, while control imaging of the brain showed no signs of residual tumor at a six-month follow-up. The patient, who did not appear immunocompromized, was referred to a hematologist and an oncologist where corticosteroids, the particular chemotherapeutic protocol and irradiation therapy were applied. Conclusion: Since PCNS lymphoma is a potentially curable brain tumor, we believe that proper selection of the management options, including early radical tumor resection for solitary PCNS lymphoma, may be proposed as a major treatment of such a tumor in selected patients, resulting in a satisfactory outcome. PMID:27703297

  11. Vapor Pressures in the Al(I)+Al2O3(s) System: Reconsidering Al2O3(s) Condensation

    NASA Technical Reports Server (NTRS)

    Copland, Evan

    2005-01-01

    The vaporization behavior of the A1-O system has been studied on numerous occasions but significant uncertainties remain. The origin of this uncertainty must be understood before A1-O vaporization behavior can be accurately determined. The condensation of A12O3 and clogging of the effusion orifice is a difficult problem for the Knudsen effusion technique that influences the measured vaporization behavior but has only received limited attention. This study reconsiders this behavior in detail. A new theory for A12O3 condensation is proposed together with procedures that will improve the measured thermodynamic properties of A1-O vaporization.

  12. Manufacture of the ALS storage ring vacuum system

    NASA Astrophysics Data System (ADS)

    Kennedy, Kurt

    1991-08-01

    The Advanced Light Source (ALS) storage ring has a 4.9 meter magnetic radius and an antechamber type vacuum chamber. These two requirements makes conventional bent tube manufacturing techniques difficult. The ALS sector vacuum chambers have been made by machining two halves out of aluminum plate and welding at the mid plane. Each of these chambers have over 50 penetrations with metal sealed flanges and seven metal sealed poppet valves which use the chamber wall as the valve seat. The sector chambers are 10 meters long and some features in the chambers must be located to .25 mm. This paper describes how and how successfully these features have been achieved.

  13. Pathway analysis of primary central nervous system lymphoma.

    PubMed

    Tun, Han W; Personett, David; Baskerville, Karen A; Menke, David M; Jaeckle, Kurt A; Kreinest, Pamela; Edenfield, Brandy; Zubair, Abba C; O'Neill, Brian P; Lai, Weil R; Park, Peter J; McKinney, Michael

    2008-03-15

    Primary central nervous system (CNS) lymphoma (PCNSL) is a diffuse large B-cell lymphoma (DLBCL) confined to the CNS. A genome-wide gene expression comparison between PCNSL and non-CNS DLBCL was performed, the latter consisting of both nodal and extranodal DLBCL (nDLBCL and enDLBCL), to identify a "CNS signature." Pathway analysis with the program SigPathway revealed that PCNSL is characterized notably by significant differential expression of multiple extracellular matrix (ECM) and adhesion-related pathways. The most significantly up-regulated gene is the ECM-related osteopontin (SPP1). Expression at the protein level of ECM-related SPP1 and CHI3L1 in PCNSL cells was demonstrated by immunohistochemistry. The alterations in gene expression can be interpreted within several biologic contexts with implications for PCNSL, including CNS tropism (ECM and adhesion-related pathways, SPP1, DDR1), B-cell migration (CXCL13, SPP1), activated B-cell subtype (MUM1), lymphoproliferation (SPP1, TCL1A, CHI3L1), aggressive clinical behavior (SPP1, CHI3L1, MUM1), and aggressive metastatic cancer phenotype (SPP1, CHI3L1). The gene expression signature discovered in our study may represent a true "CNS signature" because we contrasted PCNSL with wide-spectrum non-CNS DLBCL on a genomic scale and performed an in-depth bioinformatic analysis.

  14. Reversible Ammonia Sorption for the Primary Life Support System (PLSS)

    NASA Technical Reports Server (NTRS)

    Wojtowicz, Marek A.; Cosgrove, Joseph E.; Serio, Michael A.; Jennings, Mallory A.

    2012-01-01

    Results are presented on the development of regenerable trace-contaminant (TC) sorbent for use in Extravehicular Activities (EVAs), and more specifically in the Primary Life Support System (PLSS). Since ammonia is the most important TC to be captured, data presented in this paper are limited to ammonia sorption, with results relevant to other TCs to be reported at a later time. The currently available TC-control technology involves the use of a packed bed of acid-impregnated granular charcoal. The sorbent is non-regenerable, and its use is associated with appreciable pressure drop, i.e. power consumption. The objective of this work is to demonstrate the feasibility of using vacuum-regenerable sorbents for PLSS application. In this study, several carbon sorbent monoliths were fabricated and tested. Multiple adsorption/vacuum-regeneration cycles were demonstrated at room temperature, as well as carbon surface conditioning that enhances ammonia sorption without impairing sorbent regeneration. Depending on sorbent monolith geometry, the reduction in pressure drop with respect to granular sorbent was found to be between 50% and two orders of magnitude. Resistive heating of the carbon sorbent monolith was demonstrated by applying voltage to the opposite ends of the monolith.

  15. Comment on 'The remote sensing of ocean primary productivity - Use of a new data compilation to test satellite algorithms' by William Balch et al

    NASA Technical Reports Server (NTRS)

    Platt, Trevor; Sathyendranath, Shubha

    1993-01-01

    Various conclusions by Balch et al. (1992) about the current state of modeling primary production in the sea (lack of improvement in primary production models, since 1957, utility of analytical models, and merits or weaknesses of complex models) are commented on. It is argued that since they are based on a false premise, these conclusions are not robust, and that the approach used by Balch et al. (the model of Platt and Sathyendranath, 1988) was inadequate for the question they set out to address. The present criticism is based mainly on the issue of whether implementation was correct with respect to parameter selection. It is concluded that the findings of Balch et al. with respect to the model of Platt and Sathyendranath is unreliable. Balch replies that satellite-derived estimates of primary production should be compared directly to that measured in situ in as many regions as possible. This will provide a first-order estimate of the magnitude of the error involved in estimating primary production from space.

  16. Development of Effective Academic Affairs Administration System in Thai Primary Schools

    ERIC Educational Resources Information Center

    Thongnoi, Niratchakorn; Srisa-ard, Boonchom; Sri-ampai, Anan

    2013-01-01

    This research aimed to: 1) study current situations and problems of academic affairs administration system in Primary Schools. 2) develop an effective academic affairs administration system, and 3) evaluate the implementation of the developed system in the primary school, Thailand. Research and Development (R&D) was employed which consisted of…

  17. Modelacio de sedimentadors en plantes de tractament d'aigues residuals. Aplicacio al proces de fermentacio - elutracio de fangs primaris

    NASA Astrophysics Data System (ADS)

    Ribes Bertomeu, Josep

    the development and validation of a general settling model that allows simulating the main settling operations taking place in a WWTP, considering both primary and secondary settlers and thickeners. It consists in a one-dimensional model based on the flux theory of Kynch and the double-exponential settling function of Takacs that takes into account flocculation, hindered settling and compression processes. The model has been applied to simulation of settlers and thickeners by means of splitting the system into several horizontal layers, all of them considered as completely mixed reactors which are interconnected by mass flux obtained from the settling model. In order to simulate the conversion processes taking place during sedimentation, the general quality model BNRM1 has been added, and it has been proposed an iterative procedure for solving the equations for each layer in which the settler has been divided. The settling flux model validation, along with the quality model, has been carried out by applying them to a simulation of primary sludge fermentation - elutriation process. This process has been studied on a pilot plant located in the Carraixet WWTP in Alboraia (Valencia). In order to simulate the observed decrease in solids separation efficiency in the studied fermentation - elutriation process, the quality model has been modified with the addition of a new process called "disintegration of complex particulate material". This process influences the settleability of the sludge because it is considered that the disintegrated solids become non-settleable solids. This modification implies the addition of two new kinetic parameters (the specific disintegration velocity for volatile particulate material and the specific disintegration velocity for non volatile particulate material). However, the settling parameter that represents the non-settleable fraction of total suspended solids is eliminated from the model and it has been transformed into an experimental

  18. Primary Nocturnal Enuresis: A Structural and Strategic Family Systems Approach.

    ERIC Educational Resources Information Center

    Fletcher, Teresa B.

    2000-01-01

    Exploration of the literature regarding primary nocturnal enuresis suggests there are various causes including genetic, biological, physiological, and psychological explanations. Treatments typically consist of medication and behavioral intervention. However, it was believed that this enuretic case was caused by psychological trauma. A series of…

  19. Power Systems for Future Missions: Appendices A-L

    NASA Technical Reports Server (NTRS)

    Gill, S. P.; Frye, P. E.; Littman, Franklin D.; Meisl, C. J.

    1994-01-01

    Selection of power system technology for space applications is typically based on mass, readiness of a particular technology to meet specific mission requirements, and life cycle costs (LCC). The LCC is typically used as a discriminator between competing technologies for a single mission application. All other future applications for a given technology are usually ignored. As a result, development cost of a technology becomes a dominant factor in the LCC comparison. Therefore, it is common for technologies such as DIPS and LMR-CBC to be potentially applicable to a wide range of missions and still lose out in the initial LCC comparison due to high development costs. This collection of appendices (A through L) contains the following power systems technology plans: CBC DIPS Technology Roadmap; PEM PFC Technology Roadmap; NAS Battery Technology Roadmap; PV/RFC Power System Technology Roadmap; PV/NAS Battery Technology Roadmap; Thermionic Reactor Power System Technology Roadmap; SP-100 Power System Technology Roadmap; Dynamic SP-100 Power System Technology Roadmap; Near-Term Solar Dynamic Power System Technology Roadmap; Advanced Solar Dynamic Power System Technology Roadmap; Advanced Stirling Cycle Dynamic Isotope Power System Technology Roadmap; and the ESPPRS (Evolutionary Space Power and Propulsion Requirements System) User's Guide.

  20. A Computerized System for In-Service Formative Evaluation in Primary Care Residencies

    PubMed Central

    Beaujon, H. Jan

    1980-01-01

    A computerized system for in-service formative evaluation in primary care residencies is described. Used by three primary care residency programs at the Medical University of South Carolina, the system includes among its applications: ongoing evaluations of and by residents (rotations, monitoring, chart audits), annual in-service examinations, annual faculty and resident evaluations, and alumni surveys.

  1. Phase diagram of the Al-Er-Mo ternary system at 873 K

    NASA Astrophysics Data System (ADS)

    Pan, Yanfang; Yang, Wenchao; Tang, Chenghuang; Lan, Yanni; Zhan, Yong Zhong

    2015-11-01

    The phase relationship in the Al-Er-Mo ternary system at 873 K has been investigated based on the equilibrated method mainly by means of X-ray powder diffraction and scanning electron microscopy. The existence of 10 binary compounds and two ternary compounds has been confirmed. The results present that the isothermal section at 873 K is governed by 15 single-phase regions, 29 two-phase regions and 15 three-phase regions. By using the phase-disappearing method, Al8Mo3 has a narrow homogeneity range (from 72 to 73 at% Al), while the homogeneity range of AlMo3 is from 21% to 28.5% at% Al. Also, the maximum solubility of Al in Mo is about 16 at%.

  2. Cathode for use in high energy primary thionyl chloride cell systems and high energy primary thionyl chloride cell systems including the cathode

    NASA Astrophysics Data System (ADS)

    Walker, C. W., Jr.; Wade, W. L., Jr.; Binder, M.; Gilman, S.

    1985-08-01

    A cathode is provided for use in high energy primary lithium-thionyl chloride cell systems or calcium-thionyl chloride cell systems. The cathode comprises an expanded metallic current collector screen into which has been pasted a mixture of a low surface area conductive carbon black and a high surface area conductive carbon black previously mixed with a binder.

  3. Optimization design for the supporting system of 5m collimator primary mirror

    NASA Astrophysics Data System (ADS)

    Guan, Shaohua; Ma, Tianmeng; Zhang, Ming

    2016-10-01

    Primary mirror is an important component of collimator. The surface figure error of primary mirror is a critical factor affecting the imaging quality of collimator. Besides, the support system of primary mirror of collimator must be steady, while collimator need be moved safely as an elementary optical measuring tool. The support system of the primary mirror is composed of axial support and lateral support. Due to the axis of the primary mirror is horizontal when collimator working, the lateral support of the primary mirror has a far greater impact on the figure error of the primary mirror. In this paper, static structure analysis with finite element method is carried out for a 5m collimator primary mirror with V-block support under gravity load. With the analysis, the relationship between the structure parameters in primary mirror V-block support and the deformation of the primary mirror is built. With this relationship, the optimization parameters are found out to reduce the gravity deformation of the primary mirror.

  4. Solid state phase equilibria and intermetallic compounds of the Al-Cr-Ho system

    SciTech Connect

    Pang, Mingjun; Zhan, Yongzhong; Du, Yong

    2013-02-15

    The solid state phase equilibria of the Al-Cr-Ho ternary system at 500 Degree-Sign C were experimentally investigated. The phase relations at 500 Degree-Sign C are governed by 14 three-phase regions, 29 two-phase regions and 15 single-phase regions. The existences of 10 binary compounds and 2 ternary phases have been confirmed. Al{sub 11}Cr{sub 2}, Al{sub 11}Cr{sub 4} and Al{sub 17}Ho{sub 2} were not found at 500 Degree-Sign C. Crystal structures of Al{sub 9}Cr{sub 4} and Al{sub 8}Cr{sub 4}Ho were determined by the Rietveld X-ray powder data refinement. Al{sub 9}Cr{sub 4} was found to exhibit cubic structure with space group I4-bar 3m (no. 217) and lattice parameters a=0.9107(5) nm. Al{sub 8}Cr{sub 4}Ho crystallizes in ThMn{sub 12} structure type with space group I4/mmm (no. 139) and lattice parameters a=0.8909(4) nm, c=0.5120(5) nm. It is concluded that the obtained Al{sub 4}Cr phase in this work should be {mu}-Al{sub 4}Cr by comparing with XRD pattern of the hexagonal {mu}-Al{sub 4}Mn compound. - Graphical abstract: The solid state phase equilibria of the Al-Cr-Ho ternary system at 500 Degree-Sign C. Highlights: Black-Right-Pointing-Pointer Al-Cr-Ho system has been investigated. Black-Right-Pointing-Pointer Al{sub 9}Cr{sub 4} has cubic structure with space group I4-bar 3m. Black-Right-Pointing-Pointer Al{sub 8}Cr{sub 4}Ho crystallizes in ThMn{sub 12} type with space group I4/mmm. Black-Right-Pointing-Pointer Al{sub 4}Cr phase is {mu}-type at 500 Degree-Sign C.

  5. {sup 26}Al IN THE EARLY SOLAR SYSTEM: NOT SO UNUSUAL AFTER ALL

    SciTech Connect

    Jura, M.; Xu, S.; Young, E. D. E-mail: sxu@astro.ucla.edu

    2013-10-01

    Recently acquired evidence shows that extrasolar asteroids exhibit over a factor of 100 variation in the iron to aluminum abundance ratio. This large range likely is a consequence of igneous differentiation that resulted from heating produced by radioactive decay of {sup 26}Al with an abundance comparable to that in the solar system's protoplanetary disk at birth. If so, the conventional view that our solar system began with an unusually high amount of {sup 26}Al should be discarded.

  6. The W. M. Keck Telescope segmented primary mirror active control system

    SciTech Connect

    Jared, R.C.; Arthur, A.A.; Andreae, S.; Biocca, A.; Cohen, R.W.; Fuertes, J.M.; Franck, J.; Gabor, G.; Llacer, J.; Mast, T.; Meng, J.; Merrick, T.; Minor, R.; Nelson, J.; Orayani, M.; Salz, P.; Schaefer, B.; Witebsky, C.

    1989-07-01

    The ten meter diameter primary mirror of the W. M. Keck Telescope is a mosaic of thirty-six hexagonal mirrors. An active control system stabilizes the primary mirror. The active control system uses 168 measurements of the relative positions of adjacent mirror segments and 3 measurements of the primary mirror position in the telescope structure to control the 108 degrees of freedom needed to stabilize the figure and position of the primary mirror. The components of the active control system are relative position sensors, electronics, computers, actuators that position the mirrors, and software. The software algorithms control the primary mirror, perform star image stacking, emulate the segments, store and fit calibration data, and locate hardware defects. We give an overview of the active control system, its functional requirements and test measurements. 12 refs.

  7. Description of the primary flight display and flight guidance system logic in the NASA B-737 transport systems research vehicle

    NASA Technical Reports Server (NTRS)

    Knox, Charles E.

    1990-01-01

    A primary flight display format was integrated with the flight guidance and control system logic in support of various flight tests conducted with the NASA Transport Systems Research Vehicle B-737-100 airplane. The functional operation of the flight guidance mode control panel and the corresponding primary flight display formats are presented.

  8. Phase relations of a high-Mg basalt from the Aleutian Island arc - Implications for primary island arc basalts and high-Al basalts

    NASA Technical Reports Server (NTRS)

    Gust, D. A.; Perfit, M. R.

    1987-01-01

    An experimental investigation of a primitive high-Mg basalt, MK-15, collected from lava flows of the Unalaska Island in the Aleutian Island arc has been conducted in order to study primary and parental island arc basalts and the development of island arc magmas. The results suggest a model in which high-Al basalts are generated by moderate amounts of crystal fractionation from more primitive (high Mg/Mg + Fe, lower Al2O3) basaltic magmas near the arc crust-mantle boundary. Somewhere between 20-30 depth, significant amounts of clinopyroxene and olivine, with lesser amounts of spinel and possibly amphibole, fractionate, forming layer of olivine-clinopyroxenite at the base of the arc crust.

  9. Component Activity Measurements in the Ti-Al-O System by Knudsen Cell Mass Spectrometry

    NASA Technical Reports Server (NTRS)

    Copland, Evan; Jacobson, Nathan S.

    2003-01-01

    Titanium-aluminides (containing (alpha)2-Ti3Al and gamma-TiAl intermetallic phases) have received continued research focus due to their potential as low-density materials for structural applications at intermediate temperatures. However their application above about 850C is hindered by poor oxidation resistance, characterized by the formation of a non-protective TiO2+Al2O3 scale and an oxygen-enriched subsurface zone. Consistent with this are measured titanium and aluminum activities in "oxygen-free" titanium-aluminides, which indicate Al2O3 is only stable for aluminum concentrations greater then 54 atom percent at 1373 K. However, the inability to form a protective Al2O3 scale is in apparent conflict with phase diagram studies, as experimental isothermal sections of the Ti-Al-O system show gamma-TiAl + alpha2-Ti3Al structures are in equilibrium only with Al2O3. The apparent resolution to this conflict lies in the inclusion of oxygen effects in the thermodynamic measurements

  10. Thermodynamic assessments and inter-relationships between systems involving Al, Am, Ga, Pu, and U

    NASA Astrophysics Data System (ADS)

    Perron, A.; Turchi, P. E. A.; Landa, A.; Oudot, B.; Ravat, B.; Delaunay, F.

    2016-12-01

    A newly developed self-consistent CALPHAD thermodynamic database involving Al, Am, Ga, Pu, and U is presented. A first optimization of the slightly characterized Am-Al and completely unknown Am-Ga phase diagrams is proposed. To this end, phase diagram features as crystal structures, stoichiometric compounds, solubility limits, and melting temperatures have been studied along the U-Al → Pu-Al → Am-Al, and U-Ga → Pu-Ga → Am-Ga series, and the thermodynamic assessments involving Al and Ga alloying are compared. In addition, two distinct optimizations of the Pu-Al phase diagram are proposed to account for the low temperature and Pu-rich region controversy. The previously assessed thermodynamics of the other binary systems (Am-Pu, Am-U, Pu-U, and Al-Ga) is also included in the database and is briefly described in the present work. Finally, predictions on phase stability of ternary and quaternary systems of interest are reported to check the consistency of the database.

  11. Thermodynamic assessments and inter-relationships between systems involving Al, Am, Ga, Pu, and U

    SciTech Connect

    Perron, A.; Turchi, P. E. A.; Landa, A.; Oudot, B.; Ravat, B.; Delaunay, F.

    2016-12-01

    We present a newly developed self-consistent CALPHAD thermodynamic database involving Al, Am, Ga, Pu, and U. A first optimization of the slightly characterized Am-Al and completely unknown Am-Ga phase diagrams is proposed. To this end, phase diagram features as crystal structures, stoichiometric compounds, solubility limits, and melting temperatures have been studied along the U-Al → Pu-Al → Am-Al, and U-Ga → Pu-Ga → Am-Ga series, and the thermodynamic assessments involving Al and Ga alloying are compared. In addition, two distinct optimizations of the Pu-Al phase diagram are proposed to account for the low temperature and Pu-rich region controversy. We included the previously assessed thermodynamics of the other binary systems (Am-Pu, Am-U, Pu-U, and Al-Ga) in the database and is briefly described in the present work. In conclusion, predictions on phase stability of ternary and quaternary systems of interest are reported to check the consistency of the database.

  12. Thermodynamic assessments and inter-relationships between systems involving Al, Am, Ga, Pu, and U

    DOE PAGES

    Perron, A.; Turchi, P. E. A.; Landa, A.; ...

    2016-12-01

    We present a newly developed self-consistent CALPHAD thermodynamic database involving Al, Am, Ga, Pu, and U. A first optimization of the slightly characterized Am-Al and completely unknown Am-Ga phase diagrams is proposed. To this end, phase diagram features as crystal structures, stoichiometric compounds, solubility limits, and melting temperatures have been studied along the U-Al → Pu-Al → Am-Al, and U-Ga → Pu-Ga → Am-Ga series, and the thermodynamic assessments involving Al and Ga alloying are compared. In addition, two distinct optimizations of the Pu-Al phase diagram are proposed to account for the low temperature and Pu-rich region controversy. We includedmore » the previously assessed thermodynamics of the other binary systems (Am-Pu, Am-U, Pu-U, and Al-Ga) in the database and is briefly described in the present work. In conclusion, predictions on phase stability of ternary and quaternary systems of interest are reported to check the consistency of the database.« less

  13. Control System Modeling for the Thirty Meter Telescope Primary Mirror

    NASA Technical Reports Server (NTRS)

    MacMynowski, Douglas G.; Thompson, Peter M.; Shelton, J. Chris; Roberts, Lewis C., Jr.; Colavita, M. Mark; Sirota, Mark J.

    2011-01-01

    The Thirty Meter Telescope primary mirror is composed of 492 segments that are controlled to high precision in the presence of wind and vibration disturbances, despite the interaction with structural dynamics. The higher bandwidth and larger number of segments compared with the Keck telescopes requires greater attention to modeling to ensure success. We focus here on the development and validation of a suite of quasi-static and dynamic modeling tools required to support the design process, including robustness verification, performance estimation, and requirements flowdown. Models are used to predict the dynamic response due to wind and vibration disturbances, estimate achievable bandwidth in the presence of control-structure-interaction (CSI) and uncertainty in the interaction matrix, and simulate and analyze control algorithms and strategies, e.g. for control of focus-mode, and sensor calibration. Representative results illustrate TMT performance scaling with parameters, but the emphasis is on the modeling framework itself.

  14. Primary lymphoma of the central nervous system: a case report.

    PubMed

    Mackenzie, R A; Braye, S G

    1979-01-01

    A 46-year-old female presented with a 1-week history of mental change, confusion and headaches. Investigations revealed evidence of sterile meningitis. CAT scanning of the brain demonstrated marked contrast enhancement around the ependyma, and later examinations showed extension of the process deep into the white matter, Cerebral biopsies were non-diagnostic and, despite ventricular drainage and treatment with antibiotics and high dose steriods, the patent died. At postmortem there was extensive tumour tissue distributed in a butterfly shape around the ventricles, and microscopy revealed typical apperances of primary CNS lymphoma. On the basis of the experience of this case and a review of recent literature, it is suggested that the CAT scan appearances of this tumour are quite typical, and that cranial irradiation may be justified in the absence of specific histological diagnosis.

  15. Contribution of polymers to classical primary insulation of distribution system

    SciTech Connect

    Shwehdi, M.H.; Al-Rawi, A.

    1996-12-31

    Insulation composites used on present distribution lines frequently consist of several types of materials such as wood, porcelain, polymers and fiberglass reinforced plastics (FRP) connected in series. A study included the laboratory determination of the critical flashover voltage (CFO) of 17 single component and 90 combinations of two components were conducted. The acquired data were used to develop methods of predicting CFO levels of various multiple series electrical insulations. This paper illustrates the results and analyses of the classical primary insulation (porcelain), and of the modern-day insulation of polymers. It also presents the result of whether polymers may add or supplement insulation strength to the two dielectric combination using statistical methods. The paper also presents advantages and guidelines for the use of polymers to either replace or complement porcelain. This may help optimize the choice of dielectrics on distribution lines.

  16. Primary Dendrite Arm Spacing and Trunk Diameter in Al-7-Weight-Percentage Si Alloy Directionally Solidified Aboard the International Space Station

    NASA Technical Reports Server (NTRS)

    Ghods, M.; Tewari, S. N.; Lauer, M.; Poirier, D. R.; Grugel, R. N.

    2016-01-01

    Under a NASA-ESA collaborative research project, three Al-7-weight-percentage Si samples (MICAST-6, MICAST-7 and MICAST 2-12) were directionally solidified aboard the International Space Station to determine the effect of mitigating convection on the primary dendrite array. The samples were approximately 25 centimeters in length with a diameter of 7.8 millimeter-diameter cylinders that were machined from [100] oriented terrestrially grown dendritic Al-7Si samples and inserted into alumina ampoules within the Sample Cartridge Assembly (SCA) inserts of the Low Gradient Furnace (LGF). The feed rods were partially remelted in space and directionally solidified to effect the [100] dendrite-orientation. MICAST-6 was grown at 5 microns per second for 3.75 centimeters and then at 50 microns per second for its remaining 11.2 centimeters of its length. MICAST-7 was grown at 20 microns per second for 8.5 centimeters and then at 10 microns per second for 9 centimeters of its remaining length. MICAST2-12 was grown at 40 microns per second for 11 centimeters. The thermal gradient at the liquidus temperature varied from 22 to 14 degrees Kelvin per centimeter during growth of MICAST-6, from 26 to 24 degrees Kelvin per centimeter for MICAST-7 and from 33 to 31 degrees Kelvin per centimeter for MICAST2-12. Microstructures on the transverse sections along the sample length were analyzed to determine nearest-neighbor spacing of the primary dendrite arms and trunk diameters of the primary dendrite-arrays. This was done along the lengths where steady-state growth prevailed and also during the transients associated with the speed-changes. The observed nearest-neighbor spacings during steady-state growth of the MICAST samples show a very good agreement with predictions from the Hunt-Lu primary spacing model for diffusion controlled growth. The observed primary dendrite trunk diameters during steady-state growth of these samples also agree with predictions from a coarsening-based model

  17. Systems integration and demonstration of advanced reusable structure for ALS

    NASA Technical Reports Server (NTRS)

    Gibbins, Martin N.

    1991-01-01

    The objective was to investigate the potential of advanced material to achieve life cycle cost (LCC) benefits for reusable structure on the advanced launch system. Three structural elements were investigated - all components of an Advanced Launch System reusable propulsion/avionics module. Leading aeroshell configurations included sandwich structure using titanium, graphite/polyimide (Gr/PI), or high-temperature aluminum (HTA) face sheets. Thrust structure truss concepts used titanium, graphite/epoxy, or silicon carbide/aluminum struts. Leading aft bulkhead concepts employed graphite epoxy and aluminum. The technical effort focused on the aeroshell because the greatest benefits were expected there. Thermal analyses show the structural temperature profiles during operation. Finite element analyses show stresses during splash-down. Weight statements and manufacturing cost estimates were prepared for calculation of LCC for each design. The Gr/PI aeroshell showed the lowest potential LCC, but the HTA aeroshell was judged to be lower risk. A technology development plan was prepared to validate the applicable structural technology.

  18. An ion thruster module for primary propulsion systems.

    NASA Technical Reports Server (NTRS)

    King, H. J.; Poeschel, R. L.

    1972-01-01

    The development of a 30 cm thruster module having the operational characteristics, weight, and structural integrity consistent with flight hardware is described. Elements of the program discussed in this paper are selection of an ion optical system design, development of the discharge chamber and its control, and the results of extensive performance mapping tests. The thruster system operates at 2750 sec specific impulse at 69% over-all efficiency and can be throttled from 2.0 A to 0.16 A beam current with a control system requiring a single electrical input. The 1 kV ion beam is formed by a high perveance, two grid ion optical system.

  19. [Differences and similarities of primary care in the German and Spanish health care systems].

    PubMed

    Salvador Comino, María Rosa; Krane, Sibylla; Schelling, Jörg; Regife García, Víctor

    2016-02-01

    An efficient primary care is of particular importance for any countries' health care system. Many differences exist on how distinctive countries try to obtain the goal of an efficient, cost-effective primary care for its population. In this article we conducted a selective literature review, which includes both scientific and socio-political publications. The findings are complemented with the experience of a Spanish physician from Seville in her last year of training in family medicine, who completed a four months long rotation in the German health care system. We highlighted different features by comparing both countries, including their health care expenditure, the relation between primary and secondary care, the organization in the academic field and the training of future primary care physicians. It is clear that primary care in both countries plays a central role, have to deal with shortcomings, and in some points one system can learn from the other.

  20. Primary-secondary pumping conversion: Retrofit of an existing campus chilled water distribution system

    SciTech Connect

    Sczomak, D.P.; Nguyen, P.N.

    1996-08-01

    The chilled water distribution system within an existing 8,300 ton (29,200 kW) capacity regional chilled water plant at Michigan State University (MSU) is being converted from a primary pumping arrangement to a primary-secondary arrangement. The plant presently provides chilled water for air conditioning to twelve remote buildings. In the future, MSU plans to increase the plant`s capacity to 10,800 tons (38,000 kW) in order to serve seven more buildings. The addition of buildings to the distribution system has caused the existing primary pumps to be incapable of producing enough pressure to offset system losses at design flow rates. The existing system has become unable to concurrently provide adequate flow, design supply water temperature and efficient chiller operation due to the distribution system deficiencies. The primary-secondary pumping conversion will include modifications to the distribution piping, the addition of five variable speed secondary pumps, additions and modifications to the control systems, the trimming of impellers on six of the existing primary pumps and replacement of two primary pumps. The campus central control system will be utilized to provide automatic chiller staging, interface with the packaged secondary pump control systems, and control of the building interconnections. The total construction cost is approximately $1,400,000 and is scheduled for completion prior to the 1996 cooling season. Provisions have been made for two additional secondary pumps to accommodate the connection of additional buildings to the distribution system in the future.

  1. The evolution of interface microstructure in a ZrO[sub 2]/Ag-Cu-Al-Ti system

    SciTech Connect

    Lee, Youngmin; Yu, Jin )

    1993-08-01

    Among ceramic/metal (C/M) joining technologies, the active filler metal method has been studied extensively due to the simple brazing process and excellent joint strength. Active metal elements, typically Ti, are intentionally added to braze alloys to enhance the formation of reaction products between the ceramic and the braze metal at the C/M interface. In the brazing of Al[sub 2]O[sub 3] with the Ag-Cu-Ti filler metal, reaction products such as [gamma]-TiO, Cu[sub 2](Ti, Al)[sub 4]O, Ti[sub 3](Cu[sub 0.76]Al[sub 0.18]Sn[sub 0.06])[sub 3]O were found, while products such as Ti[sub 5]Si[sub 3] and TiN formed in the brazing of Si[sub 3]N[sub 4]. The presence of reaction layers at the C/M interface influences the interface strength in a complex way. In Cu/Al[sub 2]O[sub 3], Co/Al[sub 2]O[sub 3], Ni/Al[sub 2]O[sub 3], and Cu/diamond systems, maxima of joint strength were observed at some intermediate Ti addition, while the flexural strength decreased substantially with the thickening of the TiO layer in a ZrO[sub 2]/Ag-Cu-Sn-Ti system. Thus, composition of the braze alloy (particularly, the content of the active metal), process conditions such as brazing temperature and time, microstructure and mechanical properties of reaction products at the C/M interfaces, interfacial chemistry, and residual stress are primary factors to be studied in order to understand the strengths of the C/M interfaces systematically. In the present and the following papers, evolutions of interfacial microstructures at various brazing conditions, and corresponding interface strengths are reported, respectively, for a ZrO[sub 2]/Ag-Cu-Al-Ti system.

  2. Intention and Usage of Computer Based Information Systems in Primary Health Centers

    ERIC Educational Resources Information Center

    Hosizah; Kuntoro; Basuki N., Hari

    2016-01-01

    The computer-based information system (CBIS) is adopted by almost all of in health care setting, including the primary health center in East Java Province Indonesia. Some of softwares available were SIMPUS, SIMPUSTRONIK, SIKDA Generik, e-puskesmas. Unfortunately they were most of the primary health center did not successfully implemented. This…

  3. Vacuum system for the LBL Advanced Light Source (ALS)

    SciTech Connect

    Kennedy, K.; Henderson, T.; Meneghetti, J. )

    1989-03-01

    A 1.5 to 1.9 GeV synchrotron light source is being built at LBL. The vacuum system is designed to permit most synchrotron photons to escape the electron channel and be absorbed in an antechamber. The gas generated by the photons hitting the absorbers in the antechambers will be pumped by titanium sublimation pumps located directly under the absorbers. The electron channel and the antechamber are connected by a 10-mm-high slot that offers good electrodynamic isolation of the two chambers of frequencies affecting the store electron orbit. Twelve 10-meter-long vessels constitute the vacuum chambers for all the lattice magnets. Each chamber will be machined from two thick plates of 5083-H321 aluminum and welded at the perimeter. Machining both the inside and outside of the vacuum chamber permits the use of complex and accurate surfaces. The use of thick plates allows flanges to be machined directly into the wall of each chamber, thus avoiding much welding. 1 ref., 3 figs.

  4. Early accretion of protoplanets inferred from a reduced inner solar system (26)Al inventory.

    PubMed

    Schiller, Martin; Connelly, James N; Glad, Aslaug C; Mikouchi, Takashi; Bizzarro, Martin

    2015-06-15

    The mechanisms and timescales of accretion of 10-1000 km sized planetesimals, the building blocks of planets, are not yet well understood. With planetesimal melting predominantly driven by the decay of the short-lived radionuclide (26)Al ((26)Al→(26)Mg; t1/2 = 0.73 Ma), its initial abundance determines the permissible timeframe of planetesimal-scale melting and its subsequent cooling history. Currently, precise knowledge about the initial (26)Al abundance [((26)Al/(27)Al)0] exists only for the oldest known solids, calcium aluminum-rich inclusions (CAIs) - the so-called canonical value. We have determined the (26)Al/(27)Al of three angrite meteorites, D'Orbigny, Sahara 99555 and NWA 1670, at their time of crystallization, which corresponds to (3.98 ± 0.15)×10(-7), (3.64 ± 0.18)×10(-7), and (5.92 ± 0.59)×10(-7), respectively. Combined with a newly determined absolute U-corrected Pb-Pb age for NWA 1670 of 4564.39 ± 0.24 Ma and published U-corrected Pb-Pb ages for the other two angrites, this allows us to calculate an initial ((26)Al/(27)Al)0 of [Formula: see text] for the angrite parent body (APB) precursor material at the time of CAI formation, a value four times lower than the accepted canonical value of 5.25 × 10(-5). Based on their similar (54)Cr/(52)Cr ratios, most inner solar system materials likely accreted from material containing a similar (26)Al/(27)Al ratio as the APB precursor at the time of CAI formation. To satisfy the abundant evidence for widespread planetesimal differentiation, the subcanonical (26)Al budget requires that differentiated planetesimals, and hence protoplanets, accreted rapidly within 0.25 ± 0.15 Ma of the formation of canonical CAIs.

  5. Early accretion of protoplanets inferred from a reduced inner solar system 26Al inventory

    NASA Astrophysics Data System (ADS)

    Schiller, Martin; Connelly, James N.; Glad, Aslaug C.; Mikouchi, Takashi; Bizzarro, Martin

    2015-06-01

    The mechanisms and timescales of accretion of 10-1000 km sized planetesimals, the building blocks of planets, are not yet well understood. With planetesimal melting predominantly driven by the decay of the short-lived radionuclide 26Al (26Al→26Mg; t1/2 = 0.73 Ma), its initial abundance determines the permissible timeframe of planetesimal-scale melting and its subsequent cooling history. Currently, precise knowledge about the initial 26Al abundance [(26Al/27Al)0] exists only for the oldest known solids, calcium aluminum-rich inclusions (CAIs) - the so-called canonical value. We have determined the 26Al/27Al of three angrite meteorites, D'Orbigny, Sahara 99555 and NWA 1670, at their time of crystallization, which corresponds to (3.98 ± 0.15) ×10-7, (3.64 ± 0.18) ×10-7, and (5.92 ± 0.59) ×10-7, respectively. Combined with a newly determined absolute U-corrected Pb-Pb age for NWA 1670 of 4564.39 ± 0.24 Ma and published U-corrected Pb-Pb ages for the other two angrites, this allows us to calculate an initial (26Al/27Al)0 of (1.33-0.18+0.21) ×10-5 for the angrite parent body (APB) precursor material at the time of CAI formation, a value four times lower than the accepted canonical value of 5.25 ×10-5. Based on their similar 54Cr/52Cr ratios, most inner solar system materials likely accreted from material containing a similar 26Al/27Al ratio as the APB precursor at the time of CAI formation. To satisfy the abundant evidence for widespread planetesimal differentiation, the subcanonical 26Al budget requires that differentiated planetesimals, and hence protoplanets, accreted rapidly within 0.25 ± 0.15 Ma of the formation of canonical CAIs.

  6. Current Management of Primary Central Nervous System Lymphoma

    SciTech Connect

    Schultz, Christopher J.; Bovi, Joseph

    2010-03-01

    Primary central nervous cell lymphoma (PCNSL) is an uncommon neoplasm of the brain, leptomeninges, and rarely the spinal cord. Initially thought to be characteristically associated with congenital, iatrogenic, or acquired immunosuppression, PCNSL is now recognized with increasing frequency in immunocompetent individuals. The role of surgery is limited to establishing diagnosis, as PCNSL is often multifocal with a propensity to involve the subarachnoid space. A whole-brain radiation volume has empirically been used to adequately address the multifocal tumor frequently encountered at the time of PCNSL diagnosis. Despite high rates of response after whole-brain radiotherapy (WBRT), rapid recurrence is common and long-term survival is the exception. Chemotherapy alone or in combination with WBRT has more recently become the treatment of choice. Most effective regimens contain high-dose methotrexate and or other agents that are capable of penetrating the blood-brain barrier. High response rates and improved survival with the use of chemotherapy has led to treatment strategies that defer or eliminate WBRT in hopes of lessening the risk of neurotoxicity attributed to WBRT. Unfortunately, elimination of WBRT is also associated with a higher rate of relapse. Combined chemotherapy and WBRT regimens are now being explored that use lower total doses of radiation and altered fractionation schedules with the aim of maintaining high rates of tumor control while minimizing neurotoxicity. Pretreatment, multifactor prognostic indices have recently been described that may allow selection of treatment regimens that strike an appropriate balance of risk and benefit for the individual PCNSL patient.

  7. Postperovskite phase equilibria in the MgSiO3-Al2O3 system.

    PubMed

    Tsuchiya, Jun; Tsuchiya, Taku

    2008-12-09

    We investigate high-P,T phase equilibria of the MgSiO(3)-Al(2)O(3) system by means of the density functional ab initio computation methods with multiconfiguration sampling. Being different from earlier studies based on the static substitution properties with no consideration of Rh(2)O(3)(II) phase, present calculations demonstrate that (i) dissolving Al(2)O(3) tends to decrease the postperovskite transition pressure of MgSiO(3) but the effect is not significant ( approximately -0.2 GPa/mol% Al(2)O(3)); (ii) Al(2)O(3) produces the narrow perovskite+postperovskite coexisting P,T area (approximately 1 GPa) for the pyrolitic concentration (x(Al2O3) approximately 6 mol%), which is sufficiently responsible to the deep-mantle D'' seismic discontinuity; (iii) the transition would be smeared (approximately 4 GPa) for the basaltic Al-rich composition (x(Al2O3) approximately 20 mol%), which is still seismically visible unless iron has significant effects; and last (iv) the perovskite structure spontaneously changes to the Rh(2)O(3)(II) with increasing the Al concentration involving small displacements of the Mg-site cations.

  8. Development of a biocompatible nanodelivery system for tuberculosis drugs based on isoniazid-Mg/Al layered double hydroxide

    PubMed Central

    Saifullah, Bullo; Arulselvan, Palanisamy; El Zowalaty, Mohamed Ezzat; Fakurazi, Sharida; Webster, Thomas J; Geilich, Benjamin M; Hussein, Mohd Zobir

    2014-01-01

    The primary challenge in finding a treatment for tuberculosis (TB) is patient non-compliance to treatment due to long treatment duration, high dosing frequency, and adverse effects of anti-TB drugs. This study reports on the development of a nanodelivery system that intercalates the anti-TB drug isoniazid into Mg/Al layered double hydroxides (LDHs). Isoniazid was found to be released in a sustained manner from the novel nanodelivery system in humans in simulated phosphate buffer solutions at pH 4.8 and pH 7.4. The nanodelivery formulation was highly biocompatible compared to free isoniazid against human normal lung and 3T3 mouse fibroblast cells. The formulation was active against Mycobacterium tuberculosis and gram-positive bacteria and gram-negative bacteria. Thus results show significant promise for the further study of these nanocomposites for the treatment of TB. PMID:25336952

  9. Crystallization paths in SiO2-Al2O3-CaO system as a genotype of silicate materials

    NASA Astrophysics Data System (ADS)

    Lutsyk, V. I.; Zelenaya, A. E.

    2013-12-01

    The phases trajectories in the fields of primary crystallization of cristobalite (SiO2cr), tridymite (SiO2tr), mullite (3Al2O3-2SiO2) and in a field of liquid immiscibility are analyzed on a basis of computer model for T-x-y diagram of SiO2-Al2O3-CaO system. The concentration fields with unique set of microconstituents and the fields without individual crystallization schemes and microconstituents are revealed.

  10. Direct Metal Deposition by Laser in TiNi-Al System for Graded Structure Fabrication

    NASA Astrophysics Data System (ADS)

    Shishkovsky, I.; Kakovkina, N.; Missemer, F.

    2016-07-01

    Intermetallic phase formation was studied in powdered TiNi-Al system under layerwise laser cladding with the aim of forming a gradient of properties due to a change in the concentration relation of Al in the NiTi powder mixture from one layer to another. The relationship between the laser cladding parameters and the intermetallic phase structures in consecutively cladded layers were determined. The structure of intermetallic compounds formed by laser synthesis was studied by optical microscopy, measurement of microhardness, SEM with EDX analysis. Microhardness doubling from 500 HV to 1000 HV was achieved due to nitinol matrix enrichment by Al, which is promising for aerospace applications.

  11. Progress in systemic chemotherapy of primary breast cancer: an overview.

    PubMed

    Hortobagyi, G N

    2001-01-01

    Substantial progress has been made in the multidisciplinary management of primary breast cancer during the last 30 years. Adjuvant chemotherapy has been shown to significantly reduce the annual risk of cancer recurrence and mortality, and these effects persist even 15 years after diagnosis. Combination chemotherapy is superior to single-agent therapy and anthracycline-containing regimens. Those that combine an anthracycline with 5-fluorouracil and cyclophosphamide are more effective than regimens without an anthracycline. Six cycles of a single regimen appear to provide optimal benefit. Dose reductions below the standard range are associated with inferior results. Dose increases that require growth factor or hematopoietic stem cell support are under investigation; at this time, the existing results provide no compelling reason to use this strategy outside a clinical trial. Regimens using fixed crossover designs with two non-cross-resistant regimens are being evaluated. The addition of a taxane to anthracycline-containing regimens is currently under intense scrutiny, and preliminary analysis of the first three clinical trials has shown encouraging, albeit not compelling, results. For patients with estrogen receptor-positive breast cancer, the sequential administration of chemotherapy and 5 years of tamoxifen therapy provides additive benefits. No compelling evidence exists to combine ovarian ablation with chemotherapy. Most side effects and toxic effects are self-limited, although premature menopause requires monitoring and preventive interventions to preserve bone mineral density. The small risk of acute leukemia is of concern, and additional research to develop safer regimens is clearly indicated. The overall effect of optimal local/regional treatment combined with an anthracycline-containing adjuvant chemotherapy and a taxane (and, for patients with estrogen receptor-positive tumors, 5 years of tamoxifen therapy) is a greater than 50% reduction in annual risks of

  12. The development process for the space shuttle primary avionics software system

    NASA Technical Reports Server (NTRS)

    Keller, T. W.

    1987-01-01

    Primary avionics software system; software development approach; user support and problem diagnosis; software releases and configuration; quality/productivity programs; and software development/production facilities are addressed. Also examined are the external evaluations of the IBM process.

  13. The Al-Rich Part of the System CaO-Al 2O 3-MgO . Part I. Phase Relationships

    NASA Astrophysics Data System (ADS)

    Göbbels, M.; Woermann, E.; Jung, J.

    1995-12-01

    In the Al-rich part of the ternary system CaO-Al 2O 3MgO two new ternary phases Ca 2Mg 2Al 28O 46 (CAM-I) and CaMg 2Al 16O 27 (CAM-II) with limited solid solution ranges were found. Due to the fact that the compositions of the Mg-rich end members of these solid solutions lie on the join between hibonite (CaAl 12O 19) and spinel (MgAl 2O 4), the model of the crystal structures of these phases can be constructed by a suitable combination of hibonite and spinel units. Both phases, CAM-I and CAM-II, exhibit solid solution ranges described by a substitution mechanism also found in the binary spinel phase, MgAl 2O 4: 3 Mg 2+ = 2 Al 3+ + □. Thus the ternary phases can be expressed by the chemical formulas. Ca 2Mg 2-3 xAl 28+2 x□ xO 46 for CAM-I with 0 ≤ x ≤ 0.30 and CaMg 2-3 yAl 16+2 y□ yO 27 for CAM-II with 0 ≤ y ≤ 0.2.

  14. Speciation in the AlCl3/SO2Cl2 catholyte system.

    SciTech Connect

    Boyle, Timothy J.; Ingersoll, David T.; Tallant, David Robert; Andrews, Nicholas L.; Rodriguez, Mark Andrew; Alam, Todd Michael

    2005-02-01

    The fundamental chemical behavior of the AlCl{sub 3}/SO{sub 2}Cl{sub 2} catholyte system was investigated using {sup 27}Al NMR spectroscopy, Raman spectroscopy, and single-crystal X-ray diffraction. Three major Al-containing species were found to be present in this catholyte system, where the ratio of each was dependent upon aging time, concentration, and/or storage temperature. The first species was identified as [Cl{sub 2}Al({mu}-Cl)]{sub 2} in equilibrium with AlCl{sub 3}. The second species results from the decomposition of SO{sub 2}Cl{sub 2} which forms Cl{sub 2}(g) and SO{sub 2}(g). The SO{sub 2}(g) is readily consumed in the presence of AlCl{sub 3} to form the crystallographically characterized species [Cl{sub 2}Al({mu}-O{sub 2}SCl)]{sub 2} (1). For 1, each Al is tetrahedrally (T{sub d}) bound by two terminal Cl and two {mu}-O ligands whereas, the S is three-coordinated by two {mu}-O ligands and one terminal Cl. The third molecular species also has T{sub d}-coordinated Al metal centers but with increased oxygen coordination. Over time it was noted that a precipitate formed from the catholyte solutions. Raman spectroscopic studies show that this gel or precipitate has a component that was consistent with thionyl chloride. We have proposed a polymerization scheme that accounts for the precipitate formation. Further NMR studies indicate that the precipitate is in equilibrium with the solution.

  15. HETEROGENEOUS DISTRIBUTION OF {sup 26}Al AT THE BIRTH OF THE SOLAR SYSTEM

    SciTech Connect

    Makide, Kentaro; Nagashima, Kazuhide; Krot, Alexander N.; Huss, Gary R.; Ciesla, Fred J.; Yang, Le; Hellebrand, Eric; Gaidos, Eric

    2011-06-01

    It is believed that {sup 26}Al, a short-lived (t{sub 1/2} = 0.73 Ma) and now extinct radionuclide, was uniformly distributed in the nascent solar system (SS) with the initial {sup 26}Al/{sup 27}Al ratio of {approx}5.2 x 10{sup -5}, suggesting an external, stellar origin rather than local, solar source. However, the stellar source of {sup 26}Al and the manner in which it was injected into the SS remain controversial: the {sup 26}Al could have been produced by an asymptotic giant branch star, a supernova, or a Wolf-Rayet star and injected either into the protosolar molecular cloud, protosolar cloud core, or protoplanetary disk. Corundum (Al{sub 2}O{sub 3}) is predicted to be the first condensate from a cooling gas of solar composition. Here we show that micron-sized corundum condensates from {sup 16}O-rich ({Delta}{sup 17}O {approx} -25 per mille ) gas of solar composition recorded heterogeneous distribution of {sup 26}Al at the birth of the SS: the inferred initial {sup 26}Al/{sup 27}Al ratio ranges from {approx}6.5x10{sup -5} to <2x10{sup -6}; 52% of corundum grains measured are {sup 26}Al-poor. Abundant {sup 26}Al-poor, {sup 16}O-rich refractory objects include grossite- and hibonite-rich calcium-aluminum-rich inclusions (CAIs) in CH (high metal abundance and high iron concentration) chondrites, platy hibonite crystals in CM (Mighei-like) chondrites, and CAIs with fractionation and unidentified nuclear effects CAIs chondrites. Considering the apparently early and short duration (<0.3 Ma) of condensation of refractory {sup 16}O-rich solids in the SS, we infer that {sup 26}Al was injected into the collapsing protosolar molecular cloud and later homogenized in the protoplanetary disk. The apparent lack of correlation between {sup 26}Al abundance and O-isotope composition of corundum grains constrains the stellar source of {sup 26}Al in the SS.

  16. Operation and performance of the PEP-II prototype longitudinal damping system at ALS

    SciTech Connect

    Teytelman, D.; Claus, R.; Fox, J.

    1995-05-01

    A modular programmable longitudinal feedback system has been developed as a component of the PEP-II R+D program. This system is based on a family of VME and VXI packaged signal processing functions which implement a general purpose digital feedback controller for accelerators with bunch spacings of 2 ns. A complete PEP-II prototype system has been configured and installed for use at the LBL Advanced Light Source. The system configuration used for tests at the ALS is described and results are presented showing the action of the feedback system. Open and closed loop results showing the detection and calculation of feedback signals from bunch motion are presented and the system is shown to damp coupled-bunch instabilities in the ALS. Use of the system for accelerator diagnostics is illustrated via measurement of grow-damp transients which quantify growth rates without feedback, damping rates with feedback, and identify unstable modes.

  17. Timing and extent of Mg and Al isotopic homogenization in the early inner Solar System

    NASA Astrophysics Data System (ADS)

    Mishra, Ritesh Kumar; Chaussidon, Marc

    2014-03-01

    The first million years of the Solar System is a key period when the first solids were formed from the nebula gas. The chronology of the different processes at the origin of these solids is still largely unknown and relies strongly on the assumption made of homogeneous distribution for short-lived radioactive nuclides such as 26Al. This assumption is questioned. In this study, in situ 26Al-26Mg isotope systematics was studied with high precision in 12 calcium, aluminum-rich inclusions (CAIs) (1 type A, 2 type B, 5 type C, and 4 fine grained spinel-rich), 2 amoeboid olivine aggregates (AOAs), and 2 Al-rich chondrules from Efremovka and Vigarano. The (26Al/27Al)i in these early Solar System solids (the subscript ‘i’ stands for the initial isotope ratio obtained from the mineral 26Al isochron) range from ∼6.5×10-5 to 0.2×10-5 with δMgi*26 from -0.08 to +0.37‰. The (26Al/27Al)i and δMgi*26 of CAIs and chondrules can be explained by formation of their precursors from a homogeneous reservoir (Solar System Initial, noted hereafter SSI) with initial magnesium isotopic composition of δMgSSI*26=-0.052±0.013‰ and initial (26Al/27Al)SSI abundance of (5.62±0.42)×10-5. The high precision magnesium isotope data obtained in the present study and literature data allows identifying a few epochs of formation/reprocessing of CAIs. The time periods of these epochs correspond well with the median life times of the pre-main sequence evolution of stars of Solar mass if we anchor the (Al26/Al27)SSI=(5.62±0.42)×10-5 to the beginning of class I phase. This provides a natural explanation to the range of (26Al/27Al)i - (∼6 to 0.02) × 10-5 seen in corundum grains, FUN (Fractionation and Unidentified Nuclear Effects) CAIs, ultrarefractory CAIs, normal CAIs, and chondrules, and suggests a possible relationship between the astrophysical conditions and the formation of these early solids. Corundum grains, FUN CAIs, ultrarefractory CAIs would have formed during the class 0 of

  18. Rate and correlates of depression among elderly people attending primary health care centres in Al-Dakhiliyah governorate, Oman.

    PubMed

    Al-Sabahi, S M; Al Sinawi, H N; Al-Hinai, S S; Youssef, R M

    2014-04-03

    This study determined the rates and correlates of depression among community-dwelling elderly people, based on data from the comprehensive health assessment conducted in Al-Dakhiliyah governorate in Oman in 2008-2010. Data covered sociodemographic characteristics, medical and nutrition status, functional abilities, depression and dementia. The rate of depression was 16.9%, higher among women than men (19.3% versus 14.3%). Depression was independently predicted by the presence of social risk (OR = 3.44), dementia (OR = 3.17), impairment in activities of daily living (OR = 2.19), joint problems (OR = 1.52) and mobility restriction (OR = 1.43). If dementia was excluded from the model, depression was additionally predicted by poor perception of health (OR = 2.09), impairment in instrumental activities of daily living (OR = 1.47) and older ages of 70-< 80 years (OR = 1.63) and ≥ 80 years (OR = 1.75). Although not presenting as a complaint, depression in not uncommon among elderly people.

  19. Venous thromboembolism in systemic autoimmune diseases: A narrative review with emphasis on primary systemic vasculitides.

    PubMed

    Tamaki, Hiromichi; Khasnis, Atul

    2015-08-01

    Venous thromboembolism (VTE) is a prevalent multifactorial health condition associated with significant morbidity and mortality. Population-based epidemiological studies have revealed an association between systemic autoimmune diseases and deep venous thrombosis (DVT)/VTE. The etiopathogenesis of increased risk of VTE in systemic autoimmune diseases is not entirely clear but multiple contributors have been explored, especially in the context of systemic inflammation and disordered thrombogenesis. Epidemiologic data on increased risk of VTE in patients with primary systemic vasculitides (PSV) have accumulated in recent years and some of these studies suggest the increased risk while patients have active diseases. This could lead us to hypothesize that venous vascular inflammation has a role to play in this phenomenon, but this is unproven. The role of immunosuppressive agents in modulating the risk of VTE in patients with PSV is not yet clear except for Behçet's disease, where most of the studies are retrospective. Sensitizing physicians to this complication has implications for prevention and optimal management of patients with these complex diseases. This review will focus on the epidemiology and available evidence regarding pathogenesis, and will attempt to summarize the best available data regarding evaluation and treatment of these patients.

  20. Thermal explosion in Al-Ni system: influence of mechanical activation.

    PubMed

    White, Jeremiah D E; Reeves, Robert V; Son, Steven F; Mukasyan, Alexander S

    2009-12-03

    The influence of short-term (5-15 min) highly energetic ball milling on the ignition characteristics of a gasless heterogeneous Ni-Al reactive system has been investigated. By using Al-Ni clad particles (30-40 microm diameter Al spheres coated by a 3-3.5 microm layer of Ni, that corresponds to a 1:1 Ni/Al atomic ratio), it was shown that such mechanical treatment leads to a significant decrease in the self-ignition temperature of the system. For example, after 15 min of ball milling, the ignition temperature appears to be approximately 600 K, well below the eutectic (913 K) in the considered binary system, which is the ignition temperature for the initial clad particles. Thus, it was demonstrated that the thermal explosion process for mechanically treated reactive media can be solely defined by solid-state reactions. Additionally, thermal analysis measurements revealed that mechanical activation results in a substantial decrease in the effective activation energy (from 84 to 28 kcal/mol) of interaction between Al and Ni. This effect, that is, mechanical activation of chemical reaction, is connected to a substantial increase of contact area between reactive particles and fresh interphase boundaries formed in an inert atmosphere during ball milling. It is also important that by varying the time of mechanical activation one can precisely control the ignition temperature in high-density energetic heterogeneous systems.

  1. High Density Hydrogen Storage System Demonstration Using NaAlH4 Based Complex Compound Hydrides

    SciTech Connect

    Daniel A. Mosher; Xia Tang; Ronald J. Brown; Sarah Arsenault; Salvatore Saitta; Bruce L. Laube; Robert H. Dold; Donald L. Anton

    2007-07-27

    This final report describes the motivations, activities and results of the hydrogen storage independent project "High Density Hydrogen Storage System Demonstration Using NaAlH4 Based Complex Compound Hydrides" performed by the United Technologies Research Center under the Department of Energy Hydrogen Program, contract # DE-FC36-02AL67610. The objectives of the project were to identify and address the key systems technologies associated with applying complex hydride materials, particularly ones which differ from those for conventional metal hydride based storage. This involved the design, fabrication and testing of two prototype systems based on the hydrogen storage material NaAlH4. Safety testing, catalysis studies, heat exchanger optimization, reaction kinetics modeling, thermochemical finite element analysis, powder densification development and material neutralization were elements included in the effort.

  2. Space Shuttle Program Primary Avionics Software System (PASS) Success Legacy - Quality and Reliability Date

    NASA Technical Reports Server (NTRS)

    Orr, James K.; Peltier, Daryl

    2010-01-01

    Thsi slide presentation reviews the avionics software system on board the space shuttle, with particular emphasis on the quality and reliability. The Primary Avionics Software System (PASS) provides automatic and fly-by-wire control of critical shuttle systems which executes in redundant computers. Charts given show the number of space shuttle flights vs time, PASS's development history, and other charts that point to the reliability of the system's development. The reliability of the system is also compared to predicted reliability.

  3. Evaluation of primary stability of innovated orthodontic miniscrew system (STS): An ex-vivo study

    PubMed Central

    Seifi, Massoud

    2016-01-01

    Background Stability is determined as one of the requirements in use of Temporary Anchorage Devices (TAD) in orthodontics. Miniscrew has been a widely used Bone Anchor. Compared with mini-implant that necessitates osseointegration; mechanical retention is a determining factor for primary stability of miniscrew. Studies investigated various ways to increase primary stability. The aim of this study is to introduce a new configuration of miniscrew system which is believed to obtain more primary stability. Material and Methods Freshly ovine mandibles were cut in blocks. Twenty-seven miniscrews (diameter 1.6 × 8 mm; G2, Dual Top Anchor System, Jeil Medical, Seoul, Korea) were inserted in the blocks and divided in 2 experimental groups: single miniscrew and the innovated design “Seifi Twin Screw (STS)”. Primary stability was evaluated by Periotest “M”® device. Results Independent t-test showed a significant difference between 2 experimental groups in periotest evaluation (p< 0.05). STS demonstrated higher primary stability due to its mechanical configuration and design. Conclusions The STS provides higher primary stability and was found to be effective in increased success rate of miniscrew systems from the standpoint of primary stability. Key words:Anchorage procedures, anchorage techniques, orthodontic anchorage procedures, miniscrews, temporary anchorage device. PMID:27398174

  4. Reliability model of fault-tolerant data processing system with primary and backup nodes

    NASA Astrophysics Data System (ADS)

    Rahman, P. A.; Bobkova, E. Yu

    2016-04-01

    This paper deals with the fault-tolerant data processing systems, which are widely used in modern world of information technologies and have acceptable overhead expenses in hardware implementation. A simplified reliability model for duplex systems and the offered by authors advanced model for data processing systems with primary and backup nodes based on a three-state model of recoverable elements, which takes into consideration different failure rates of passive and active nodes and finite time of node activation, are also given. A calculation formula for the availability factor of the dual-node data processing system with primary and backup nodes and calculation examples are also provided.

  5. 40 CFR 141.544 - What if my system uses chloramines, ozone, or chlorine dioxide for primary disinfection?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ..., ozone, or chlorine dioxide for primary disinfection? 141.544 Section 141.544 Protection of Environment... Benchmark § 141.544 What if my system uses chloramines, ozone, or chlorine dioxide for primary disinfection? If your system uses chloramines, ozone or chlorine dioxide for primary disinfection your system...

  6. 40 CFR 141.544 - What if my system uses chloramines, ozone, or chlorine dioxide for primary disinfection?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ..., ozone, or chlorine dioxide for primary disinfection? 141.544 Section 141.544 Protection of Environment... Benchmark § 141.544 What if my system uses chloramines, ozone, or chlorine dioxide for primary disinfection? If your system uses chloramines, ozone or chlorine dioxide for primary disinfection your system...

  7. 40 CFR 141.544 - What if my system uses chloramines, ozone, or chlorine dioxide for primary disinfection?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ..., ozone, or chlorine dioxide for primary disinfection? 141.544 Section 141.544 Protection of Environment... Benchmark § 141.544 What if my system uses chloramines, ozone, or chlorine dioxide for primary disinfection? If your system uses chloramines, ozone or chlorine dioxide for primary disinfection your system...

  8. 40 CFR 141.544 - What if my system uses chloramines, ozone, or chlorine dioxide for primary disinfection?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ..., ozone, or chlorine dioxide for primary disinfection? 141.544 Section 141.544 Protection of Environment... Benchmark § 141.544 What if my system uses chloramines, ozone, or chlorine dioxide for primary disinfection? If your system uses chloramines, ozone or chlorine dioxide for primary disinfection your system...

  9. 40 CFR 141.544 - What if my system uses chloramines, ozone, or chlorine dioxide for primary disinfection?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ..., ozone, or chlorine dioxide for primary disinfection? 141.544 Section 141.544 Protection of Environment... Benchmark § 141.544 What if my system uses chloramines, ozone, or chlorine dioxide for primary disinfection? If your system uses chloramines, ozone or chlorine dioxide for primary disinfection your system...

  10. Process for preparing high-transition-temperature superconductors in the Nb-Al-Ge system

    DOEpatents

    Giorgi, A.L.; Szklarz, E.G.

    1973-01-30

    The patent describes a process for preparing superconducting materials in the Nb-Al-Ge system having transition temperatures in excess of 19K. The process comprises premixing powdered constituents, pressing them into a plug, heating the plug to 1,450-1,800C for 30 minutes to an hour under vacuum or an inert atmosphere, and annealing at moderate temperatures for reasonably long times (approximately 50 hours). High transition-temperature superconductors, including those in the Nb3(Al,Ge) system, prepared in accordance with this process exhibit little degradation in the superconducting transition temperature on being ground to -200 mesh powder. (GRA)

  11. Structural and electronic properties of the graphene/Al/Ni(111) intercalation system

    NASA Astrophysics Data System (ADS)

    Voloshina, E. N.; Generalov, A.; Weser, M.; Böttcher, S.; Horn, K.; Dedkov, Yu S.

    2011-11-01

    Decoupling of the graphene layer from the ferromagnetic substrate via intercalation of sp metal has recently been proposed as an effective way to realize a single-layer graphene-based spin-filter. Here, the structural and electronic properties of the prototype system, graphene/Al/Ni(111), are investigated via a combination of electron diffraction and spectroscopic methods. These studies are accompanied by state-of-the-art electronic structure calculations. The properties of this prospective Al-intercalation-like system and its possible implementations in future graphene-based devices are discussed.

  12. Phase equilibria and structural investigations in the system Al-Fe-Si.

    PubMed

    Marker, Martin C J; Skolyszewska-Kühberger, Barbara; Effenberger, Herta S; Schmetterer, Clemens; Richter, Klaus W

    2011-12-01

    The Al-Fe-Si system was studied for an isothermal section at 800 °C in the Al-rich part and at 900 °C in the Fe-rich part, and for half a dozen vertical sections at 27, 35, 40, 50 and 60 at.% Fe and 5 at.% Al. Optical microscopy and powder X-ray diffraction (XRD) was used for initial sample characterization, and Electron Probe Microanalysis (EPMA) and Scanning Electron Microscopy (SEM) of the annealed samples was used to determine the exact phase compositions. Thermal reactions were studied by Differential Thermal Analysis (DTA). Our experimental results are generally in good agreement with the most recent phase diagram versions of the system Al-Fe-Si. A new ternary high-temperature phase τ12 (cF96, NiTi2-type) with the composition Al48Fe36Si16 was discovered and was structurally characterized by means of single-crystal and powder XRD. The variation of the lattice parameters of the triclinic phase τ1 with the composition Al2+x Fe3Si3-x (-0.3 < x < 1.3) was studied in detail. For the binary phase FeSi2 only small solubility of Al was found in the low-temperature modification LT-FeSi2 (ζβ ) but significant solubility in the high-temperature modification HT-FeSi2 (ζα ) (8.5 at.% Al). It was found that the high-temperature modification of FeSi2 is stabilized down to much lower temperature in the ternary, confirming earlier literature suggestions on this issue. DTA results in four selected vertical sections were compared with calculated sections based on a recent CALPHAD assessment. The deviations of liquidus values are significant suggesting the need for improvement of the thermodynamic models.

  13. Simulation of primary-slag melting behavior in the cohesive zone of a blast furnace, considering the effect of Al{sub 2}O{sub 3}, Fe{sub t}O, and basicity in the sinter ore

    SciTech Connect

    Hino, Mitsutaka; Nagasaka, Tetsuya; Katsumata, Akitoshi; Higuchi, Kenichi; Yamaguchi, Kazuyoshi; Kon-No, Norimitsu

    1999-08-01

    The alumina content in the iron ore imported to Japan is increasing year by year, and some problems in blast furnace operation, due to the use of the high-alumina-containing sinter, have already been reported. In order to clarify the mechanism of the harmful effect of alumina on the blast furnace operation, the behavior of the primary melt, which is formed in the sinter at the cohesive zone of the blast furnace, has been simulated by dripping slag through an iron or oxide funnel. The effects of basicity, Al{sub 2}O{sub 3}, and Fe{sub t}O contents in the five slag systems on the dripping temperature and weight of slag remaining on the funnel have been discussed. It was found that the eutectic melt formed in the sinter would play an important role in the dripping behavior of the slag in the blast furnace through the fine porosity of the reduced iron and ore particles. Al{sub 2}O{sub 3} increased the weight of the slag remaining on the funnel, and its effect became very significant in the acidic and low-Fe{sub t}O-containing slag. It was estimated that the increase of the weight of the slag remaining on the funnel by Al{sub 2}O{sub 3} in the ore could result in a harmful effect on the permeability resistance and an indirect reduction rate of the sinter in the blast furnace.

  14. AlGaInN laser diode technology and systems for defence and security applications

    NASA Astrophysics Data System (ADS)

    Najda, Stephen P.; Perlin, Piotr; Suski, Tadek; Marona, Lujca; Boćkowski, Mike; Leszczyński, Mike; Wisniewski, Przemek; Czernecki, Robert; Kucharski, Robert; Targowski, Grzegorz; Watson, Scott; Kelly, Antony E.

    2015-10-01

    AlGaInN laser diodes is an emerging technology for defence and security applications such as underwater communications and sensing, atomic clocks and quantum information. The AlGaInN material system allows for laser diodes to be fabricated over a very wide range of wavelengths from u.v., ~380nm, to the visible ~530nm, by tuning the indium content of the laser GaInN quantum well. Thus AlGaInN laser diode technology is a key enabler for the development of new disruptive system level applications in displays, telecom, defence and other industries. Ridge waveguide laser diodes are fabricated to achieve single mode operation with optical powers up to 100mW with the 400-440nm wavelength range with high reliability. Visible free-space and underwater communication at frequencies up to 2.5GHz is reported using a directly modulated 422nm GaN laser diode. Low defectivity and highly uniform GaN substrates allow arrays and bars to be fabricated. High power operation operation of AlGaInN laser bars with up to 20 emitters have been demonstrated at optical powers up to 4W in a CS package with common contact configuration. An alternative package configuration for AlGaInN laser arrays allows for each individual laser to be individually addressable allowing complex free-space or optical fibre system integration with a very small form-factor.

  15. Neurocognitive Features Distinguishing Primary Central Nervous System Lymphoma from Other Possible Causes of Rapidly Progressive Dementia

    PubMed Central

    Deutsch, Mariel B.; Mendez, Mario F.

    2015-01-01

    Objective Define the neurocognitive features of primary central nervous system lymphoma (PCNSL) presenting with dementia, and compare with other causes of rapidly progressive dementia (RPD). Background PCNSL can present as an RPD. Differentiating PCNSL from other RPDs is critical because lymphomatous dementia may be reversible, and untreated PCNSL is fatal. Methods We performed a meta-analysis of case reports of dementia from PCNSL (between 1950 and 2013); 20 patients (14 with lymphomatosis cerebri) met our criteria. We compared these patients to a case series of patients with RPD from Creutzfeldt-Jakob disease and other non-PCNSL etiologies (Sala et al, 2012. Alzheimer Dis Assoc Disord. 26:267–271). Results Median age was 66 (range 41–81); 70% were men. Time from symptom onset to evaluation was < 6 months in 65%. No patients had seizures; 5% had headaches; 45% had non-aphasic speech difficulty. There was significantly more memory impairment in patients with PCNSL than other RPDs and significantly less myoclonus and parkinsonism. Behavioral changes and cerebellar signs were not significantly different. Significantly more patients with PCNSL than other RPDs had white matter changes; significantly fewer had atrophy. Elevated CSF protein and pleocytosis were more frequent in PCNSL; patients with other RPDs tended to have normal CSF ± 14-3-3 protein. Conclusions Unlike patients with RPD from other causes, those with PCNSL commonly present with impaired memory, apathy, and abnormal speech and gait, without headache, seizure, or myoclonus. White-matter changes and CSF abnormalities predominate. Improved clinical awareness of PCNSL can prompt earlier diagnosis and treatment. PMID:25812125

  16. Implementation of coulometric titration system at constant current for developing of certified materials as primary standards

    NASA Astrophysics Data System (ADS)

    Suarez, H.; Cristancho, R.; Peralta, F.; Torres, H.

    2017-01-01

    Coulometry is a primary method for measuring high purity substances. This is used to certify the primary reference materials required in a chemical analysis process. This paper describes the coulometric titration system developed by the National Metrology Institute (NMI) of Colombia for the certification of hydrochloric acid 0.1mol/kg reference materials. In addition, it also shows preliminary studies for future development of potassium chloride (KCl) and ethylenediaminetetraacetic acid disodium salt (EDTA-Na2) certification.

  17. Role for primary cilia as flow detectors in the cardiovascular system.

    PubMed

    Van der Heiden, Kim; Egorova, Anastasia D; Poelmann, Robert E; Wentzel, Jolanda J; Hierck, Beerend P

    2011-01-01

    The cardiovascular system is exposed to biochemical and biomechanical signals. Various sensors for these signals have been described and they contribute to cardiovascular development, maintenance of vessel integrity during adult life, and to pathogenesis. In the past 10years, primary cilia, membrane-covered, rod-like cellular protrusions, were discovered on multiple cell types of the cardiovascular system. Primary cilia are sensory organelles involved in several key (developmental) signaling pathways and in chemo- and mechanosensing on a myriad of cell types. In the embryonic and adult cardiovascular system, they have been demonstrated to function as shear stress sensors on endothelial cells and could act as strain sensors on smooth muscle cells and cardiomyocytes and as chemosensors on fibroblasts. This review will cover their occurrence and elaborate on established and possible functions of primary cilia in the cardiovascular system.

  18. Wettability and phase formation in the TiC{sub x}/Al system

    SciTech Connect

    Frumin, N.; Frage, N.; Polak, M.; Dariel, M.P.

    1997-10-15

    The introduction of reinforcements such as carbide or oxide ceramics into a metallic matrix improves high temperature strength, creep resistance and low temperature toughness. Modification of the ceramic phase can also be used in order to improve wetting in a metal/ceramic system. The wettability of ceramic surfaces by metallic melts is strongly dependent on the stoichiometry of the ceramic compound (oxide or carbide). Titanium carbide has a wide range of stability (0.55 < C/Ti {le} 1), and its chemical, physical and mechanical properties largely depend on the composition. For instance, chemical inertness and hardness increase with increasing C/Ti ratio. The use of TiC as a reinforcing phase in aluminum alloys or in TiC/Al cermets has not been exploited fully. Titanium carbide exhibits adequate wetting by Al{sub (L)} due to chemical interactions at high temperatures that may also lead to the formation of the Al{sub 4}C{sub 3} phase. The presence of this phase at the interface is undesirable because it is weak and brittle. Moreover, Al{sub 4}C{sub 3} decomposes in the presence of water to form Al{sub 2}O{sub 3} and methane gas. The present work was aimed at finding the proper conditions and the Ti/C ratio in non-stoichiometric TiC{sub x} that would improve wetting and prevent the formation of Al{sub 4}C{sub 3}.

  19. Gender Differences in the Primary Representational System according to Neurolinguistic Programming.

    ERIC Educational Resources Information Center

    Cassiere, M. F.; And Others

    Neurolinguistic Programming (NLP) is a currently popular therapeutic modality in which individuals organize information through three basic sensory systems, one of which is the Primary Representational System (PRS). This study was designed to investigate gender differences in PRS according to the predicate preference method. It was expected that…

  20. Relationships between Digestive, Circulatory, and Urinary Systems in Portuguese Primary Textbooks

    ERIC Educational Resources Information Center

    Carvalho, Graça S.; Clèment, Pierre

    2007-01-01

    In this study, 63 Portuguese primary schoolbooks (1920-2005) were analyzed. The analysis focused on text information (reference to blood absorption and association of the digestive system to other human systems) and on information from images (presence or absence of image "confusion" (when the sequence of the digestive tract is not…

  1. Composition Optimization of Al-DOPING Lithium Manganese Oxide from Al2O3-Li2CO3-MnO2 Ternary System

    NASA Astrophysics Data System (ADS)

    He, Gang; Sun, Xinyan; Hong, Jianhe; He, Mingzhong

    2013-07-01

    In order to synthesize eutectic compound of Al doping lithium manganese oxide which can be used as cathode material in lithium battery, using γ-Al2O3, Li2CO3 and MnO2 as starting raw materials, the composition optimization research work has been done by the solid state synthesis method. A limited composition range was found in Al2O3-Li2CO3-MnO2 ternary system, in which the synthesized Al doping lithium manganese oxides have single spinel structure and good electrochemical performance. The results showed that the LiAl0.04Mn1.96O4 material presented better charge-discharge cycling behavior than pure LiMn2O4, and showed the best electrochemistry property among the compounds in the Al2O3-Li2O-Mn2O3 ternary system. LiAl0.04Mn1.96O4 still kept perfect cubic structure, but LiMn2O4 kept the coexistence of the cubic and tetragonal phases after 50 charge-discharge cycles.

  2. Critical Assessment and Thermodynamic Modeling of the Al-Fe-O System

    NASA Astrophysics Data System (ADS)

    Shishin, Denis; Prostakova, Viktoria; Jak, Evgueni; Decterov, Sergei A.

    2016-02-01

    A complete literature review, critical evaluation, and thermodynamic modeling of the phase diagrams and thermodynamic properties of phases in the Al-Fe-O system at 1 atm total pressure are presented. Optimized model equations for the thermodynamic properties of all phases are obtained, which reproduce all available thermodynamic and phase-equilibrium data within experimental error limits from 298.15 K (25 °C) to above the liquidus temperatures at all compositions and oxygen partial pressures from metal saturation to 1 atm. The complex phase relationships in the system have been elucidated, and discrepancies among the data have been resolved. The database of the model parameters can be used along with software for Gibbs-energy minimization in order to calculate all thermodynamic properties and any type of phase diagram section. The modified quasichemical model was used for the liquid oxide phase. A sublattice model, based upon the Compound Energy Formalism, was developed for spinel, which expands from magnetite, Fe3O4, to hercynite, FeAl2O4. The distribution of cations between octahedral and tetrahedral sites and oxygen nonstoichiometry in spinel are taken into account. The model for metallic liquid assumes random mixing of associates: Fe, Al, O, AlO, and Al2O. It describes well the minimum that is observed on the solubility of oxygen in liquid iron as a function of the Al content. The solid solution between hematite and corundum exhibiting a miscibility gap, as well as a small solubility of Al2O3 in wüstite are quantitatively described by a simple Bragg-Williams model.

  3. Integration of Oral Health into Primary Health Care System: Views of Primary Health Care Workers in Lagos State, Nigeria

    PubMed Central

    Ogunbodede, Eyitope; Adeniyi, Abiola

    2014-01-01

    The limited access to oral health care in developing countries can be greatly improved by integrating oral health into the Primary Health Care (PHC) system. This study was designed to assess the views of PHC workers on integrating oral health care into the PHC system. A self-administered questionnaire survey was conducted in two selected local government areas of Lagos State. The instrument contained three sections assessing sociodemographic features, knowledge of common oral diseases and views on integration of oral health into PHC respectively. The mean knowledge score was 7.75 (SD=±1.81), while 60.4% of the respondents had average knowledge scores. Educational status (P=0.018) and designation (P=0.033) were significantly related to the mean knowledge scores. There was no significant difference in the oral health knowledge of the various cadres (P=0.393). Majority (85.4%) of the respondents were willing to include oral health education in their job schedule and 82% believed they needed more training on oral health. The knowledge of the respondents on the causes of the common oral diseases was deficient. Oral health education should be included in the future curriculum of these personnel. PMID:28299117

  4. Synthesis of MAX Phases in the Zr-Ti-Al-C System.

    PubMed

    Tunca, Bensu; Lapauw, Thomas; Karakulina, Olesia M; Batuk, Maria; Cabioc'h, Thierry; Hadermann, Joke; Delville, Rémi; Lambrinou, Konstantina; Vleugels, Jozef

    2017-03-20

    This study reports on the synthesis and characterization of MAX phases in the (Zr,Ti)n+1AlCn system. The MAX phases were synthesized by reactive hot pressing and pressureless sintering in the 1350-1700 °C temperature range. The produced ceramics contained large fractions of 211 and 312 (n = 1, 2) MAX phases, while strong evidence of a 413 (n = 3) stacking was found. Moreover, (Zr,Ti)C, ZrAl2, ZrAl3, and Zr2Al3 were present as secondary phases. In general, the lattice parameters of the hexagonal 211 and 312 phases followed Vegard's law over the complete Zr-Ti solid solution range, but the 312 phase showed a non-negligible deviation from Vegard's law around the (Zr0.33,Ti0.67)3Al1.2C1.6 stoichiometry. High-resolution scanning transmission electron microscopy combined with X-ray diffraction demonstrated ordering of the Zr and Ti atoms in the 312 phase, whereby Zr atoms occupied preferentially the central position in the close-packed M6X octahedral layers. The same ordering was also observed in 413 stackings present within the 312 phase. The decomposition of the secondary (Zr,Ti)C phase was attributed to the miscibility gap in the ZrC-TiC system.

  5. Kr implantation into heavy ion irradiated monolithic U-Mo/Al systems: SIMS and SEM investigations

    NASA Astrophysics Data System (ADS)

    Zweifel, T.; Valle, N.; Grygiel, C.; Monnet, I.; Beck, L.; Petry, W.

    2016-03-01

    Worldwide, high performance research and material test reactors are aiming to convert their fuel from high enriched uranium towards low enriched ones. High density U-Mo/Al based nuclear fuels are considered as a promising candidate for this conversion. However, during in-pile test irradiations, the formation of an interdiffusion layer (IDL) between the U-Mo and the Al matrix is observed, caused by irradiation enhanced U-Al interdiffusion processes. This IDL accumulates fission gases at the IDL/matrix interfaces. Together, these two effects strongly reduce the performance of this new fuel type. Recently, the out-of-pile technique of heavy ion irradiation (127I) on U-Mo/Al layer systems proved to be an alternative to time-consuming in-pile test irradiations for certain fuel behaviour aspects. Here we present SIMS and SEM investigations of non-conventional 82Kr implantation into previously heavy ion irradiated U-Mo/Al layer systems. It is shown that Kr accumulates inside μm large porosities at the IDL/matrix interfaces. This critical accumulation of μm-sized large gas bubbles is directly related to the presence of the irradiation induced IDL. Without IDL no critical accumulation of fission gas bubbles occurs.

  6. New investigation of phase equilibria in the system Al-Cu-Si.

    PubMed

    Ponweiser, Norbert; Richter, Klaus W

    2012-01-25

    The phase equilibria and invariant reactions in the system Al-Cu-Si were investigated by a combination of optical microscopy, powder X-ray diffraction (XRD), differential thermal analysis (DTA) and electron probe micro analysis (EPMA). Isothermal phase equilibria were investigated within two isothermal sections. The isothermal section at 500 °C covers the whole ternary composition range and largely confirms the findings of previous phase diagram investigations. The isothermal section at 700 °C describes phase equilibria only in the complex Cu-rich part of the phase diagram. A new ternary compound τ was found in the region between (Al,Cu)-γ(1) and (Cu,Si)-γ and its solubility range was determined. The solubility of Al in κ-CuSi was found to be extremely high at 700 °C. In contrast, no ternary solubility in the β-phase of Cu-Al was found, although this phase is supposed to form a complete solid solution according to previous phase diagram assessments. Two isopleths, at 10 and 40 at.% Si, were investigated by means of DTA and a partial ternary reaction scheme (Scheil diagram) was constructed, based on the current work and the latest findings in the binary systems Al-Cu and Cu-Si. The current study shows that the high temperature equilibria in the Cu-rich corner are still poorly understood and additional studies in this area would be favorable.

  7. A Study of Phase Composition and Structure of Alloys of the Al - Mg - Si - Fe System

    NASA Astrophysics Data System (ADS)

    Mailybaeva, A. D.; Zolotorevskii, V. S.; Smagulov, D. U.; Islamkulov, K. M.

    2017-03-01

    The Thermo-Calc software is used to compute the phase transformations occurring during cooling of alloys. Polythermal and isothermal sections of the phase diagram of the Al - Mg - Si - Fe system are plotted. The phase composition and the structure of aluminum alloys in cast condition and after a heat treatment are studied experimentally.

  8. Comparison of the Mismatch Repair System between Primary and Metastatic Colorectal Cancers Using Immunohistochemistry

    PubMed Central

    Jung, Jiyoon; Kang, Youngjin; Lee, Yoo Jin; Kim, Eojin; Ahn, Bokyung; Lee, Eunjung; Kim, Joo Young; Lee, Jeong Hyeon; Lee, Youngseok; Kim, Chul Hwan; Chae, Yang-Seok

    2017-01-01

    Background Colorectal cancer (CRC) is one of the most common malignancies worldwide. Approximately 10%–15% of the CRC cases have defective DNA mismatch repair (MMR) genes. Although the high level of microsatellite instability status is a predictor of favorable outcome in primary CRC, little is known about its frequency and importance in secondary CRC. Immunohistochemical staining (IHC) for MMR proteins (e.g., MLH1, MSH2, MSH6, and PMS2) has emerged as a useful technique to complement polymerase chain reaction (PCR) analyses. Methods In this study, comparison between the MMR system of primary CRCs and paired liver and lung metastatic lesions was done using IHC and the correlation with clinical outcomes was also examined. Results Based on IHC, 7/61 primary tumors (11.4%) showed deficient MMR systems, while 13/61 secondary tumors (21.3%) showed deficiencies. In total, 44 cases showed proficient expression in both the primary and metastatic lesions. Three cases showed deficiencies in both the primary and paired metastatic lesions. In 10 cases, proficient expression was found only in the primary lesions, and not in the corresponding metastatic lesions. In four cases, proficient expression was detected in the secondary tumor, but not in the primary tumor. Conclusions Although each IHC result and the likely defective genes were not exactly matched between the primary and the metastatic tumors, identical results for primary and metastatic lesions were obtained in 77% of the cases (47/61). These data are in agreement with the previous microsatellite detection studies that used PCR and IHC. PMID:28192899

  9. Early accretion of protoplanets inferred from a reduced inner solar system 26Al inventory

    PubMed Central

    Schiller, Martin; Connelly, James N.; Glad, Aslaug C.; Mikouchi, Takashi; Bizzarro, Martin

    2016-01-01

    The mechanisms and timescales of accretion of 10–1000 km sized planetesimals, the building blocks of planets, are not yet well understood. With planetesimal melting predominantly driven by the decay of the short-lived radionuclide 26Al (26Al→26Mg; t1/2 = 0.73 Ma), its initial abundance determines the permissible timeframe of planetesimal-scale melting and its subsequent cooling history. Currently, precise knowledge about the initial 26Al abundance [(26Al/27Al)0] exists only for the oldest known solids, calcium aluminum-rich inclusions (CAIs) – the so-called canonical value. We have determined the 26Al/27Al of three angrite meteorites, D’Orbigny, Sahara 99555 and NWA 1670, at their time of crystallization, which corresponds to (3.98 ± 0.15)×10−7, (3.64 ± 0.18)×10−7, and (5.92 ± 0.59)×10−7, respectively. Combined with a newly determined absolute U-corrected Pb–Pb age for NWA 1670 of 4564.39 ± 0.24 Ma and published U-corrected Pb–Pb ages for the other two angrites, this allows us to calculate an initial (26Al/27Al)0 of (1.33−0.18+0.21)×10−5 for the angrite parent body (APB) precursor material at the time of CAI formation, a value four times lower than the accepted canonical value of 5.25 × 10−5. Based on their similar 54Cr/52Cr ratios, most inner solar system materials likely accreted from material containing a similar 26Al/27Al ratio as the APB precursor at the time of CAI formation. To satisfy the abundant evidence for widespread planetesimal differentiation, the subcanonical 26Al budget requires that differentiated planetesimals, and hence protoplanets, accreted rapidly within 0.25 ± 0.15 Ma of the formation of canonical CAIs. PMID:27429474

  10. Thermodynamics of greenhouse systems for the northern latitudes: analysis, evaluation and prospects for primary energy saving.

    PubMed

    Bronchart, Filip; De Paepe, Michel; Dewulf, Jo; Schrevens, Eddie; Demeyer, Peter

    2013-04-15

    In Flanders and the Netherlands greenhouse production systems produce economically important quantities of vegetables, fruit and ornamentals. Indoor environmental control has resulted in high primary energy use. Until now, the research on saving primary energy in greenhouse systems has been mainly based on analysis of energy balances. However, according to the thermodynamic theory, an analysis based on the concept of exergy (free energy) and energy can result in new insights and primary energy savings. Therefore in this paper, we analyse the exergy and energy of various processes, inputs and outputs of a general greenhouse system. Also a total system analysis is then performed by linking the exergy analysis with a dynamic greenhouse climate growth simulation model. The exergy analysis indicates that some processes ("Sources") lie at the origin of several other processes, both destroying the exergy of primary energy inputs. The exergy destruction of these Sources is caused primarily by heat and vapour loss. Their impact can be compensated by exergy input from heating, solar radiation, or both. If the exergy destruction of these Sources is reduced, the necessary compensation can also be reduced. This can be accomplished through insulating the greenhouse and making the building more airtight. Other necessary Sources, namely transpiration and loss of CO2, have a low exergy destruction compared to the other Sources. They are therefore the best candidate for "pump" technologies ("vapour heat pump" and "CO2 pump") designed to have a low primary energy use. The combination of these proposed technologies results in an exergy efficient greenhouse with the highest primary energy savings. It can be concluded that exergy analyses add additional information compared to only energy analyses and it supports the development of primary energy efficient greenhouse systems.

  11. 40 CFR 141.535 - What if my system uses chloramines, ozone, or chlorine dioxide for primary disinfection?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ..., ozone, or chlorine dioxide for primary disinfection? 141.535 Section 141.535 Protection of Environment... § 141.535 What if my system uses chloramines, ozone, or chlorine dioxide for primary disinfection? If your system uses chloramines, ozone, or chlorine dioxide for primary disinfection, you must...

  12. 40 CFR 141.535 - What if my system uses chloramines, ozone, or chlorine dioxide for primary disinfection?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ..., ozone, or chlorine dioxide for primary disinfection? 141.535 Section 141.535 Protection of Environment... § 141.535 What if my system uses chloramines, ozone, or chlorine dioxide for primary disinfection? If your system uses chloramines, ozone, or chlorine dioxide for primary disinfection, you must...

  13. 40 CFR 141.535 - What if my system uses chloramines, ozone, or chlorine dioxide for primary disinfection?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ..., ozone, or chlorine dioxide for primary disinfection? 141.535 Section 141.535 Protection of Environment... § 141.535 What if my system uses chloramines, ozone, or chlorine dioxide for primary disinfection? If your system uses chloramines, ozone, or chlorine dioxide for primary disinfection, you must...

  14. 40 CFR 141.535 - What if my system uses chloramines, ozone, or chlorine dioxide for primary disinfection?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ..., ozone, or chlorine dioxide for primary disinfection? 141.535 Section 141.535 Protection of Environment... § 141.535 What if my system uses chloramines, ozone, or chlorine dioxide for primary disinfection? If your system uses chloramines, ozone, or chlorine dioxide for primary disinfection, you must...

  15. 40 CFR 141.535 - What if my system uses chloramines, ozone, or chlorine dioxide for primary disinfection?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ..., ozone, or chlorine dioxide for primary disinfection? 141.535 Section 141.535 Protection of Environment... § 141.535 What if my system uses chloramines, ozone, or chlorine dioxide for primary disinfection? If your system uses chloramines, ozone, or chlorine dioxide for primary disinfection, you must...

  16. High Temperature Aerogels in the Al2O3-SiO2 System

    NASA Technical Reports Server (NTRS)

    Hurwitz, Frances I.; Aranda, Denisse V.; Gallagher, Meghan E.

    2008-01-01

    Al2O3-SiO2 aerogels are of interest as constituents of thermal insulation systems for use at high temperatures. Al2O3 and mullite aerogels are expected to crystallize at higher temperatures than their SiO2 counterparts, hence avoiding the shrinkages that accompany the formation of lower temperature SiO2 phases and preserving pore structures into higher temperature regimes. The objective of this work is to determine the influence of processing parameters on shrinkage, gel structure (including surface area, pore size and distribution) and pyrolysis behavior.

  17. Direct Evidence of Nanometric Invasionlike Grain Boundary Penetration in the Al/Ga System

    SciTech Connect

    Pereiro-Lopez, E.; Cloetens, P.; Ludwig, W.; Bellet, D.; Lemaignan, C.

    2005-11-18

    We report the first in situ results of deformation during grain boundary penetration in the Al/Ga system, obtained with a novel, nondestructive hard x-ray synchrotron projection microscopy technique. Focusing the beam to a state-of-the-art spot size of 90x90 nm{sup 2}, we demonstrate that penetration is accompanied by continuous relative separation of the Al grains of the same final amplitude as the final Ga layer thickness in the absence of external stress. The formation of nanometric intergranular liquid layers is originated by a crack propagation process and inherently implies the presence of weak stress levels.

  18. The Microstructure-Processing-Property Relationships in an Al Matrix Composite System Reinforced by Al-Cu-Fe Alloy Particles

    SciTech Connect

    Tang, Fei

    2004-01-01

    Metal matrix composites (MMC), especially Al matrix composites, received a lot of attention during many years of research because of their promise for the development of automotive and aerospace materials with improved properties and performance, such as lighter weight and better structural properties, improved thermal conductivity and wear resistance. In order to make the MMC materials more viable in various applications, current research efforts on the MMCs should continue to focus on two important aspects, including improving the properties of MMCs and finding more economical techniques to produce MMCs. Solid state vacuum sintering was studied in tap densified Al powder and in hot quasi-isostatically forged samples composed of commercial inert gas atomized or high purity Al powder, generated by a gas atomization reaction synthesis (GARS) technique. The GARS process results in spherical Al powder with a far thinner surface oxide. The overall results indicated the enhanced ability of GARS-processed Al and Al alloy powders for solid state sintering, which may lead to simplification of current Al powder consolidation processing methods. Elemental Al-based composites reinforced with spherical Al-Cu-Fe alloy powders were produced by quasi-isostatic forging and vacuum hot pressing (VHP) consolidation methods. Microstructures and tensile properties of AYAl-Cu-Fe composites were characterized. It was proved that spherical Al-Cu-Fe alloy powders can serve as an effective reinforcement particulate for elemental Al-based composites, because of their high hardness and a preferred type of matrix/reinforcement interfacial bonding, with reduced strain concentration around the particles. Ultimate tensile strength and yield strength of the composites were increased over the corresponding Al matrix values, far beyond typical observations. This remarkable strengthening was achieved without precipitation hardening and without severe strain hardening during consolidation because of

  19. RASC-AL (Revolutionary Aerospace Systems Concepts-Academic Linkage): 2002 Advanced Concept Design Presentation

    NASA Technical Reports Server (NTRS)

    2002-01-01

    The Revolutionary Aerospace Systems Concepts-Academic Linkage (RASC-AL) is a program of the Lunar and Planetary Institute (LPI) in collaboration with the Universities Space Research Association's (USRA) ICASE institute through the NASA Langley Research Center. The RASC-AL key objectives are to develop relationships between universities and NASA that lead to opportunities for future NASA research and programs, and to develop aerospace systems concepts and technology requirements to enable future NASA missions. The program seeks to look decades into the future to explore new mission capabilities and discover what's possible. NASA seeks concepts and technologies that can make it possible to go anywhere, at anytime, safely, reliably, and affordably to accomplish strategic goals for science, exploration, and commercialization. University teams were invited to submit research topics from the following themes: Human and Robotic Space Exploration, Orbital Aggregation & Space Infrastructure Systems (OASIS), Zero-Emissions Aircraft, and Remote Sensing. RASC-AL is an outgrowth of the HEDS-UP (University Partners) Program sponsored by the LPI. HEDS-UP was a program of the Lunar and Planetary Institute designed to link universities with NASA's Human Exploration and Development of Space (HEDS) enterprise. The first RASC-AL Forum was held November 5-8, 2002, at the Hilton Cocoa Beach Oceanfront Hotel in Cocoa Beach, Florida. Representatives from 10 university teams presented student research design projects at this year's Forum. Each team contributed a written report and these reports are presented.

  20. Apotopes and innate immune system: novel players in the primary biliary cirrhosis scenario.

    PubMed

    Lleo, Ana; Invernizzi, Pietro

    2013-08-01

    Our understanding of primary biliary cirrhosis has been rapidly growing over the past decade and the disease is now regarded as a model for other female-predominant, organ-specific autoimmune conditions. Primary biliary cirrhosis ensues from a multi-lineage loss of tolerance to the E2 component of the pyruvate dehydrogenase complex. One of the major unanswered questions in the pathogenesis of primary biliary cirrhosis is the specificity of small intrahepatic bile ducts attack while PDC-E2 is present in mitochondria of all nucleated cells. Recent findings suggest that the uniqueness of the primary target tissue, biliary epithelium, may be of considerable importance for understanding primary biliary cirrhosis and that the biliary epithelial cell is more than an innocent victim. Rather, it attracts an immune attack by virtue of the unique apoptotic mechanisms and by the way it handles PDC-E2. Moreover, recent evidence suggests that apoptotic bodies of biliary epithelial cell are able to activate the innate immune system in the presence of anti-mitochondrial antibodies. This review article is intended to provide a critical overview of the role of apoptosis in biliary epithelial cells, the activation of the innate immune system, and its biological and clinical significance in primary biliary cirrhosis.

  1. 75 FR 36689 - United States, et al. v. Election Systems & Software, Inc.; Public Comments and Response on...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-28

    ... Antitrust Division United States, et al. v. Election Systems & Software, Inc.; Public Comments and Response... United States, et al. v. Election Systems & Software Inc., Case No. 1:10-00380-JDB, which were filed in.... Election Systems and Software, Inc., Defendant. Case No.: 1:10-cv-00380 Judge: Bates, John D. Deck...

  2. Central nervous system compromise in primary Sjögren's syndrome.

    PubMed

    Anaya, Juan-Manuel; Villa, Luis A; Restrepo, Lucas; Molina, Jose F; Mantilla, Rubén D; Vargas, Sergio

    2002-08-01

    Central nervous system (CNS) involvement in primary Sjögren's syndrome (SS) is poorly understood, and its frequency as well as its manifestations are subjects of controversy. The current study was undertaken to determine the prevalence and the clinical and immunogenetic characteristics of CNS compromise in a well defined group of patients with primary SS. In this retrospective study, patients fulfilled the European classification criteria. Among 120 patients with primary SS, 3 (2.5%) had CNS compromise (multiple sclerosis-like illness, complicated migraine, and optic neuritis with epilepsy). The CNS involvement coincided with the onset of sicca symptoms in 1 case. All 3 patients carried the human leukocyte antigen (HLA) DQB1*0303 allele and tested positive for anti-Ro antibodies, but not for anti-cardiolipin antibodies. Although rare, CNS compromise in primary SS can be the presenting manifestation of the disease in a few cases, and may be severe and varied.

  3. A new ordered tetragonal phase in the Ti3Al+Nb system

    NASA Technical Reports Server (NTRS)

    Hsiung, L. M.; Wadley, H. N. G.

    1992-01-01

    Results are reported from an experimental study of phase stability in a plasma-sprayed Ti3Al+Nb alloy using TEM and electron diffraction techniques. The alloys was produced from Ti3Al+Nb powder via an inductively coupled plasma deposition process. Evidence was found for the ordering of the B2 phase to a structure similar to the DO3-type phase, but with a tetragonal distortion. An ordered tetragonal phase (T) is proposed to account for these observations, and the existence of the B2 - T ordering transformation in the Ti3Al+Nb system is suggested. The T phase can be regarded as a DO3-like phase with a tetragonal distortion. The tegragonality c0/a0 is approximately equal to 1.02, and a0 equals 0.65 +/-0.01 nm.

  4. Fabrication of NiAl intermetallic reactors for microtechnology-based energy chemical systems (MECS)

    SciTech Connect

    Alman, D.A.; Wilson, R.D.; Paul, B.K.

    2001-01-01

    Microtechnology-based energy chemical systems (MECS) offer opportunities for portable power generation, on-site waste remediation, point-of-use chemical synthesis, and heat-transfer. The material requirements for this application include chemical inertness and the ability to be fabricated into structures that contain internal features of complex geometries and small (<250 micrometer) dimensions. It has been recognized that materials with limited formability, like ceramics and intermetallics, may be required for high temperature applications. In this paper, a method for forming an array of internal microchannels in a NiAl device is presented. Microchannels are precision machined (via laser ablation) into elemental Ni and Al foils. During bonding, these foils are converted into NiAl. Results show that this is a viable method for producing aluminide-based structure containing complex, internal features.

  5. Ultrasound assisted combustion synthesis of TiC in Al-Ti-C system.

    PubMed

    Liu, Zhiwei; Rakita, Milan; Xu, Wilson; Wang, Xiaoming; Han, Qingyou

    2015-11-01

    This research investigated the effects of high-intensity ultrasound on the combustion synthesis of TiC particles in Al-Ti-C system. The process involved that high-intensity ultrasound was applied on the surface of a compacted Al-Ti-C pellet directly through a Nb probe during the thermal explosion reaction. By comparing with the sample without ultrasonic treatment, it was found that the thermal explosion reaction for synthesizing TiC phase could take place thoroughly in the ultrasonically treated sample. During the process of synthesizing TiC phase, the dissolution of solid graphite particles into the Al-Ti melt, as well as the nucleation and growth of TiC particles could be promoted effectively due to the effects of ultrasound, leading to an enhancement of the formation of TiC particles. Ultrasound assisted combustion synthesis as a simple and effective approach was proposed for synthesizing materials in this research.

  6. Comparison of Carbon and Hi-Z Primary Collimators for the LHC Phase II Collimation System

    SciTech Connect

    Keller, Lewis; Markiewicz, Thomas; Smith, Jeffrey; Assmann, Ralph; Bracco, Chiara; Weiler, Thomas; /Karlsruhe, Inst. Technol.

    2011-10-31

    A current issue with the LHC collimation system is single-diffractive, off-energy protons from the primary collimators that pass completely through the secondary collimation system and are absorbed immediately downbeam in the cold magnets of the dispersion suppressor section. Simulations suggest that the high impact rate could result in quenching of these magnets. We have studied replacing the 60 cm primary graphite collimators, which remove halo mainly by inelastic strong interactions, with 5.25 mm tungsten, which remove halo mainly by multiple coulomb scattering and thereby reduce the rate of single-diffractive interactions that cause losses in the dispersion suppressor.

  7. Primary Systemic Amyloidosis and High Levels of Angiotensin-Converting Enzyme: Two Case Reports

    PubMed Central

    Praena-Segovia, J.; Sanchez-Gastaldo, A.; Bernabeu-Wittel, M.; Ocete-Pérez, R.; Ávila-Polo, R.; Martino, M. L.

    2013-01-01

    Infiltrative heart diseases are caused by a heterogeneous group of disorders; amyloidosis and sarcoidosis are two frequent causes of myocardial infiltration, which differ in clinical and biological outcome and treatment issues. The presence of high levels of angiotensin-converting enzyme (ACE) in a patient with infiltrative heart disease may increase suspicion of sarcoidosis. Nevertheless, no mention about increased ACE levels in extracerebral primary systemic amyloidosis is available. We present two cases of primary systemic amyloidosis, which are cardiac involvement and elevated ACE levels. PMID:24826302

  8. A systems-based partnership learning model for strengthening primary healthcare

    PubMed Central

    2013-01-01

    Background Strengthening primary healthcare systems is vital to improving health outcomes and reducing inequity. However, there are few tools and models available in published literature showing how primary care system strengthening can be achieved on a large scale. Challenges to strengthening primary healthcare (PHC) systems include the dispersion, diversity and relative independence of primary care providers; the scope and complexity of PHC; limited infrastructure available to support population health approaches; and the generally poor and fragmented state of PHC information systems. Drawing on concepts of comprehensive PHC, integrated quality improvement (IQI) methods, system-based research networks, and system-based participatory action research, we describe a learning model for strengthening PHC that addresses these challenges. We describe the evolution of this model within the Australian Aboriginal and Torres Strait Islander primary healthcare context, successes and challenges in its application, and key issues for further research. Discussion IQI approaches combined with system-based participatory action research and system-based research networks offer potential to support program implementation and ongoing learning across a wide scope of primary healthcare practice and on a large scale. The Partnership Learning Model (PLM) can be seen as an integrated model for large-scale knowledge translation across the scope of priority aspects of PHC. With appropriate engagement of relevant stakeholders, the model may be applicable to a wide range of settings. In IQI, and in the PLM specifically, there is a clear role for research in contributing to refining and evaluating existing tools and processes, and in developing and trialling innovations. Achieving an appropriate balance between funding IQI activity as part of routine service delivery and funding IQI related research will be vital to developing and sustaining this type of PLM. Summary This paper draws together

  9. Primary Care Behavioral Health Provider Training: Systematic Development and Implementation in a Large Medical System.

    PubMed

    Dobmeyer, Anne C; Hunter, Christopher L; Corso, Meghan L; Nielsen, Matthew K; Corso, Kent A; Polizzi, Nicholas C; Earles, Jay E

    2016-09-01

    The expansion of integrated, collaborative, behavioral health services in primary care requires a trained behavioral health workforce with specific competencies to deliver effective, evidence-informed, team-based care. Most behavioral health providers do not have training or experience working as primary care behavioral health consultants (BHCs), and require structured training to function effectively in this role. This article discusses one such training program developed to meet the needs of a large healthcare system initiating widespread implementation of the primary care behavioral health model of service delivery. It details the Department of Defense's experience in developing its extensive BHC training program, including challenges of addressing personnel selection and hiring issues, selecting a model for training, developing and implementing a phased training curriculum, and improving the training over time to address identified gaps. Future directions for training improvements and lessons learned in a large healthcare system are discussed.

  10. Quasiparticle band structure for the Hubbard systems: Application to. alpha. -CeAl sub 2

    SciTech Connect

    Costa-Quintana, J.; Lopez-Aguilar, F. ); Balle, S. ); Salvador, R. Supercomputer Computations Research Institute, Florida State University, Tallahassee, Florida 32306-4052 )

    1990-04-01

    A self-energy formalism for determining the quasiparticle band structure of the Hubbard systems is deduced. The self-energy is obtained from the dynamically screened Coulomb interaction whose bare value is the correlation energy {ital U}. A method for integrating the Schroedingerlike equation with the self-energy operator is given. The method is applied to the cubic Laves phase of {alpha}-CeAl{sub 2} because it is a clear Hubbard system with a very complex electronic structure and, moreover, this system provides us with sufficient experimental data for testing our method.

  11. Vapor/Mist Used to Lubricate Gears After Loss of Primary Lubrication System

    NASA Technical Reports Server (NTRS)

    Handschuh, Robert F.; Morales, Wilfredo

    2001-01-01

    Loss of lubrication in rotorcraft drive systems is a demanding requirement placed on drive system manufacturers. The drive system must operate for at least 30 minutes once the primary lubrication system has failed. This test is a military requirement that must be passed prior to certification of the aircraft. As new aircraft engines, operating at higher speeds, are fielded, the requirements for the drive system become increasingly more difficult. Also, the drive system must be lightweight, which minimizes the opportunity to use the gear bodies to absorb the tremendous amount of heating that takes place. In many cases, the amount of heat generated because of the high speed and load requires an emergency lubrication system that negatively impacts the aircraft's weight, complexity, and cost. A single mesh spur gear test rig is being used at the NASA Glenn Research Center to investigate possible emergency lubrication system improvements that will minimize the impact of having these systems onboard rotorcraft. A technique currently being investigated uses a vapor/mist system to lubricate the contacting surfaces after the primary lubrication system has been shut down. A number of tests were conducted in which the vapor/mist used the same lubricant as the primary system, but at a greatly reduced flow rate. Each test was initiated with the primary lubrication system operational and at steady-state conditions for a given speed and load. Then the primary lubrication system was shut down, and the vapor/mist lubrication system was initiated. An example of the tests conducted is shown in the figures. These preliminary tests have uncovered a mechanism that provides a lubricious, carbonaceous solid on the surface that actually reduces the surface temperature of the meshing gear teeth during operation. Surface analysis of the carbonaceous solid revealed it was graphitic. This mechanism is the synthetic lubricant "coking" on the active profile of the gears, which reduces the

  12. Primary healthcare in transition – a qualitative study of how managers perceived a system change

    PubMed Central

    2013-01-01

    Background Primary healthcare in Sweden has undergone widespread reforms in recent years, including freedom of choice regarding provider, freedom of establishment and increased privatisation. The key aims of the reforms were to strengthen the role of the patient and improve performance in terms of access and responsiveness. The aim of this study was to explore how managers at publicly owned primary healthcare centres perceived the transition of the primary healthcare system and the impact it has had on their work. Methods In this qualitative study, 24 managers of publicly owned primary healthcare centres in the metropolitan region of Gothenburg were recruited. Semi-structured interviews were conducted and data were analysed using content analysis inspired by Silverman. Results The analysis revealed two core themes: The transition is perceived as a rapid change, enforced mainly through financial incentives and Prioritisation conflicts arise between patient groups with different needs, demands and levels of empowerment. The transition has produced powerful and rapid effects that were considered to be both positive and negative. While the new financial incentives were seen as a driving force and a tool for change, they also became a stress factor due to uncertainty, competition with other primary healthcare centres and negative feelings associated with staff cutbacks. The shift in power towards the patient improved access and service but also led to more patients with unreasonable demands. Managers found it difficult to prioritise correctly between patient groups with different needs, demands and levels of empowerment and they were concerned about potentially negative effects on less empowered patients, e.g. multi-morbid patients. Managers also experienced shortcomings in their change management skills. Conclusions This qualitative study shows the complexity of the system change and describes the different effects and perceptions of the transition from a manager

  13. A new classification system for primary lymphatic dysplasias based on phenotype.

    PubMed

    Connell, F; Brice, G; Jeffery, S; Keeley, V; Mortimer, P; Mansour, S

    2010-05-01

    Traditional classification systems for lymphoedema are of limited use for the diagnosis of specific forms of primary lymphoedema. The understanding of primary lymphoedema has been impeded by confusing terminology and a tendency to simply divide patients into three categories based on the age of onset: lymphoedema congenita manifests at or shortly after birth, lymphoedema praecox is apparent before the age of 35 years and lymphoedema tarda manifests thereafter. The clinical presentation in the spectrum of primary lymphoedema disorders is very variable; the phenotypes of primary lymphoedema conditions vary in the age of onset, site of the oedema, inheritance patterns, associated features and genetic causes. Different inheritance patterns are recognised and there are numerous associated anomalies. Some subgroups, such as Milroy disease and Lymphoedema distichiasis, are well characterised, but others are not. A new clinical classification for primary lymphoedema has been developed as a diagnostic algorithm. Its use is demonstrated on 333 probands referred to our lymphoedema clinic. Grouping patients by accurate phenotyping facilitates molecular investigations, understanding of inheritance patterns, and the natural history of different types of primary lymphoedema. Descriptions of the diagnostic categories, some of which have not been previously clearly defined as distinct clinical entities, are illustrated by clinical cases.

  14. Release and systemic accumulation of heavy metals from preformed crowns used in restoration of primary teeth.

    PubMed

    Kodaira, Hiroe; Ohno, Kohachiro; Fukase, Naoko; Kuroda, Midori; Adachi, Shiki; Kikuchi, Motohiro; Asada, Yoshinobu

    2013-01-01

    Preformed crowns for restoration of primary teeth are used in various treatments and are essential for restoring the crowns of primary molars. However, there are concerns that mechanical, chemical, and thermal stimulation may cause release of components of such crowns. We examined systemic accumulation of heavy metals associated with preformed crowns (3M Stainless Steel Primary Molar Crowns) used in primary tooth restoration. The participants were 37 children who had visited the Pediatric Dental Clinic of Tsurumi University Dental Hospital. They were divided into two groups: 22 participants without a history of being fitted with a preformed crown for primary tooth restoration (controls), and 15 participants with preformed crowns for primary tooth restoration. Analysis of hair samples showed a significant difference in the level of the trace element Cr - an important component of the preformed crowns - between children with and without preformed crowns, but no significant differences in Fe or Ni levels. Levels of the trace elements Ni, Cr, and Fe were within allowable ranges, indicating that these minerals were not likely to be harmful.

  15. Heterogeneous distribution of 26Al at the birth of the solar system: Evidence from refractory grains and inclusions

    NASA Astrophysics Data System (ADS)

    Krot, A. N.; Makide, K.; Nagashima, K.; Huss, G. R.; Ogliore, R. C.; Ciesla, F. J.; Yang, L.; Hellebrand, E.; Gaidos, E.

    2012-12-01

    Abstract-We review recent results on O- and Mg-isotope compositions of refractory grains (corundum, hibonite) and calcium, aluminum-rich inclusions (CAIs) from unequilibrated ordinary and carbonaceous chondrites. We show that these refractory objects originated in the presence of nebular gas enriched in 16O to varying degrees relative to the standard mean ocean water value: the Δ17OSMOW value ranges from approximately -16‰ to -35‰, and recorded heterogeneous distribution of 26<span class="hlt">Al</span> in their formation region: the inferred (26<span class="hlt">Al</span>/27<span class="hlt">Al</span>)0 ranges from approximately 6.5 × 10-5 to <2 × 10-6. There is no correlation between O- and Mg-isotope compositions of the refractory objects: 26<span class="hlt">Al</span>-rich and 26<span class="hlt">Al</span>-poor refractory objects have similar O-isotope compositions. We suggest that 26<span class="hlt">Al</span> was injected into the 26<span class="hlt">Al</span>-poor collapsing protosolar molecular cloud core, possibly by a wind from a neighboring massive star, and was later homogenized in the protoplanetary disk by radial mixing, possibly at the canonical value of 26<span class="hlt">Al</span>/27<span class="hlt">Al</span> ratio (approximately 5 × 10-5). The 26<span class="hlt">Al</span>-rich and 26<span class="hlt">Al</span>-poor refractory grains and inclusions represent different generations of refractory objects, which formed prior to and during the injection and homogenization of 26<span class="hlt">Al</span>. Thus, the duration of formation of refractory grains and CAIs cannot be inferred from their 26<span class="hlt">Al</span>-26Mg systematics, and the canonical (26<span class="hlt">Al</span>/27<span class="hlt">Al</span>)0 does not represent the initial abundance of 26<span class="hlt">Al</span> in the solar <span class="hlt">system</span>; instead, it may or may not represent the average abundance of 26<span class="hlt">Al</span> in the fully formed disk. The latter depends on the formation time of CAIs with the canonical 26<span class="hlt">Al</span>/27<span class="hlt">Al</span> ratio relative to the timing of complete delivery of stellar 26<span class="hlt">Al</span> to the solar <span class="hlt">system</span>, and the degree of its subsequent homogenization in the disk. The injection of material containing 26<span class="hlt">Al</span> resulted in no observable changes in O-isotope composition of the solar <span class="hlt">system</span>. Instead, the variations in O-isotope compositions between individual</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=19800047753&hterms=aloe&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D20%26Ntt%3Daloe','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=19800047753&hterms=aloe&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D20%26Ntt%3Daloe"><span><span class="hlt">Al</span>-26 from red giants. [connections with anomalous Mg-26 content in meteorites and solar <span class="hlt">system</span> formation</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Norgaard, H.</p> <p>1980-01-01</p> <p>Simplified models of thermally pulsing red giants are investigated, with particular emphasis on predicting the extent to which nuclear processing at the base of the convective envelope in conjunction with processing in the thermally unstable He shell can synthesize <span class="hlt">Al</span>-26 (tau/1/2/ = 7.2 x 10 to the 5th yr). Values of <span class="hlt">Al</span>-26/<span class="hlt">Al</span>-27 of about 0.5-1, with <span class="hlt">Al</span>-27/<span class="hlt">Al</span>-27(solar) of about 1-2, are predicted in some cases. It is pointed out that such results can lead to isotope shifts in the absorption lines of <span class="hlt">Al</span>H and <span class="hlt">Al</span>O, which should be observationally identifiable in some late-type supergiants. The possible connection with the anomalous Mg-26 content (assigned to the decay of <span class="hlt">Al</span>-26) detected in some meteorites and the connection with formation of the solar <span class="hlt">system</span> are also touched on.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=neurolinguistic+AND+programming&pg=5&id=EJ297736','ERIC'); return false;" href="http://eric.ed.gov/?q=neurolinguistic+AND+programming&pg=5&id=EJ297736"><span>Assessing <span class="hlt">Primary</span> Representational <span class="hlt">System</span> (PRS) Preference for Neurolinguistic Programming (NLP) Using Three Methods.</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Dorn, Fred J.</p> <p>1983-01-01</p> <p>Considered three methods of identifying <span class="hlt">Primary</span> Representational <span class="hlt">System</span> (PRS)--an interview, a word list, and a self-report--in a study of 120 college students. Results suggested the three methods offer little to counselors either collectively or individually. Results did not validate the PRS construct, suggesting the need for further research.…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=neurolinguistic+AND+programming&pg=4&id=EJ291139','ERIC'); return false;" href="http://eric.ed.gov/?q=neurolinguistic+AND+programming&pg=4&id=EJ291139"><span>Assessment of <span class="hlt">Primary</span> Representational <span class="hlt">Systems</span> with Neurolinguistic Programming: Examination of Preliminary Literature.</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Dorn, Fred J.; And Others</p> <p>1983-01-01</p> <p>Reviews the inconsistent findings of studies on neurolinguistic programing and recommends some areas that should be examined to verify various claims. Discusses methods of assessing client's <span class="hlt">primary</span> representational <span class="hlt">systems</span>, including predicate usage and eye movements, and suggests that more reliable methods of assessing PRS must be found. (JAC)</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://files.eric.ed.gov/fulltext/EJ1086212.pdf','ERIC'); return false;" href="http://files.eric.ed.gov/fulltext/EJ1086212.pdf"><span>Development of Quality Assurance <span class="hlt">System</span> in Culture and Nation Character Education in <span class="hlt">Primary</span> Education in Indonesia</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Susilana, Rudi; Asra</p> <p>2013-01-01</p> <p>The purpose of national education is to develop skills and build dignified national character and civilization in educating nation life (Act No. 20, 2003). The paper describes a <span class="hlt">system</span> of quality assurance in culture and character education in <span class="hlt">primary</span> education. This study employs the six sigma model which consists of the formula DMAIC (Define,…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=Intimate+AND+relationships&pg=4&id=EJ1075703','ERIC'); return false;" href="http://eric.ed.gov/?q=Intimate+AND+relationships&pg=4&id=EJ1075703"><span>Job Realities of <span class="hlt">Primary</span> School Principals in Greece: Similarities and Variations in a Highly Centralized <span class="hlt">System</span></span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Dimopoulos, Kostas; Dalkavouki, Katerina; Koulaidis, Vasilis</p> <p>2015-01-01</p> <p>This study aims at investigating <span class="hlt">primary</span> school principals' work on a daily basis in order to understand the ways in which the centralized educational <span class="hlt">system</span> affects their practices. Four typical cases of principals were selected and asked to keep daily records for a period of four months. Data from logs were complemented with data collected…</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_9");'>9</a></li> <li><a href="#" onclick='return showDiv("page_10");'>10</a></li> <li class="active"><span>11</span></li> <li><a href="#" onclick='return showDiv("page_12");'>12</a></li> <li><a href="#" onclick='return showDiv("page_13");'>13</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_11 --> <div id="page_12" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_10");'>10</a></li> <li><a href="#" onclick='return showDiv("page_11");'>11</a></li> <li class="active"><span>12</span></li> <li><a href="#" onclick='return showDiv("page_13");'>13</a></li> <li><a href="#" onclick='return showDiv("page_14");'>14</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="221"> <li> <p><a target="_blank" onclick="trackOutboundLink('http://files.eric.ed.gov/fulltext/EJ1068617.pdf','ERIC'); return false;" href="http://files.eric.ed.gov/fulltext/EJ1068617.pdf"><span>Investigating Nigerian <span class="hlt">Primary</span> School Teachers' Preparedness to Adopt Personal Response <span class="hlt">System</span> in ESL Classroom</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Agbatogun, Alaba Olaoluwakotansibe</p> <p>2012-01-01</p> <p>This study investigated the extent to which computer literacy dimensions (computer general knowledge, documents and documentations, communication and surfing as well as data inquiry), computer use and academic qualification as independent variables predicted <span class="hlt">primary</span> school teachers' attitude towards the integration of Personal Response <span class="hlt">System</span> in…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=MAMMOGRAPHY&pg=2&id=EJ692530','ERIC'); return false;" href="http://eric.ed.gov/?q=MAMMOGRAPHY&pg=2&id=EJ692530"><span>Office <span class="hlt">Systems</span> and Their Influence on Mammography Use in Rural and Urban <span class="hlt">Primary</span> Care</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Engelman, Kimberly K.; Ellerbeck, Edward F.; Perpich, Denise; Nazir, Niaman; McCarter, Kevin; Ahluwalia, Jasjit S.</p> <p>2004-01-01</p> <p>Breast cancer screening rates are lower in rural communities. Although studies have addressed barriers to mammography for rural residents, physician practice barriers have received less attention. Purpose: Controlled clinical trials have shown that the use of office reminder <span class="hlt">systems</span> in <span class="hlt">primary</span> care practices is related to increased clinical care…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://files.eric.ed.gov/fulltext/EJ1079832.pdf','ERIC'); return false;" href="http://files.eric.ed.gov/fulltext/EJ1079832.pdf"><span>Using a Learning Management <span class="hlt">System</span> to Personalise Learning for <span class="hlt">Primary</span> School Students</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Edmunds, Bronwyn; Hartnett, Maggie</p> <p>2014-01-01</p> <p>This paper reports on one aspect of a descriptive multiple-case study which set out to explore the role of a learning management <span class="hlt">system</span> (LMS) in personalising learning for students from the perspective of three teachers in one <span class="hlt">primary</span> school in New Zealand. The intention was to provide insight into the role the LMS could play in classrooms when…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://hdl.handle.net/2060/19740022381','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/19740022381"><span>Space shuttle/food <span class="hlt">system</span> study. Volume 2, Appendix F: Flight food and <span class="hlt">primary</span> packaging</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p></p> <p>1974-01-01</p> <p>The analysis and selection of food items and <span class="hlt">primary</span> packaging, the development of menus, the nutritional analysis of diet, and the analyses of alternate food mixes and contingency foods is reported in terms of the overall food <span class="hlt">system</span> design for space shuttle flight. Stowage weights and cubic volumes associated with each alternate mix were also evaluated.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.osti.gov/scitech/servlets/purl/1337537','SCIGOV-STC'); return false;" href="http://www.osti.gov/scitech/servlets/purl/1337537"><span>Investigating Power <span class="hlt">System</span> <span class="hlt">Primary</span> and Secondary Reserve Interaction under High Wind Power Penetration</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Zhang, Yingchen; Tan, Jin; Krad, Ibrahim; Yang, Rui; Gevorgian, Vahan; Ela, Erik</p> <p>2016-12-01</p> <p>Power <span class="hlt">system</span> frequency needs to be maintained close to its nominal value at all times to successfully balance load and generation and maintain <span class="hlt">system</span> reliability. Adequate <span class="hlt">primary</span> frequency response and secondary frequency response are the <span class="hlt">primary</span> forces to correct an energy imbalance at the second-to-minute level. As wind energy becomes a larger portion of the world's energy portfolio, there is an increased need for wind to provide frequency response. This paper addresses one of the major concerns about using wind for frequency regulation: the unknown factor of the interaction between <span class="hlt">primary</span> and secondary reserves. The lack of a commercially available tool to model this has limited the energy industry's understanding of when the depletion of <span class="hlt">primary</span> reserves will impact the performance of secondary response or vice versa. This paper investigates the issue by developing a multi-area frequency response integration tool with combined <span class="hlt">primary</span> and secondary capabilities. The simulation is conducted in close coordination with economical energy scheduling scenarios to ensure credible simulation results.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/scitech/biblio/21494107','SCIGOV-STC'); return false;" href="https://www.osti.gov/scitech/biblio/21494107"><span>A new phase in the <span class="hlt">system</span> lithium-aluminum: Characterization of orthorhombic Li{sub 2}<span class="hlt">Al</span></span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Puhakainen, Kati; Bostroem, Magnus; Groy, Thomas L.; Haeussermann, Ulrich</p> <p>2010-11-15</p> <p>Investigation of the Li rich part of the binary Li-<span class="hlt">Al</span> <span class="hlt">system</span> revealed the existence of a new phase, orthorhombic Li{sub 2}<span class="hlt">Al</span>, which is isostructural to Li{sub 2}Ga and Li{sub 2}In. The crystal structure was determined from single crystal X-ray diffraction data (Cmcm, a=4.658(2) A, b=9.767(4) A, c=4.490(2) A, Z=4). Refinement of atomic position site occupancies yielded a composition Li{sub 1.92}<span class="hlt">Al</span>{sub 1.08} (64 at% Li) indicating a small homogeneity range, Li{sub 2-x}<span class="hlt">Al</span>{sub 1+x}. Li{sub 2}<span class="hlt">Al</span> is the peritectic decomposition product of the stoichiometric compound Li{sub 9}<span class="hlt">Al</span>{sub 4}, which is stable below 270{+-}2 {sup o}C. Li{sub 2}<span class="hlt">Al</span> itself decomposes peritectically to Li{sub 3}<span class="hlt">Al</span>{sub 2} and Li rich melt at 335{+-}2 {sup o}C. The discovery of Li{sub 2}<span class="hlt">Al</span> (Li{sub 2-x}<span class="hlt">Al</span>{sub 1+x}) settles a long standing inconsistency in the Li-<span class="hlt">Al</span> phase diagram which was based on the assumption that Li{sub 9}<span class="hlt">Al</span>{sub 4} possesses a high temperature modification. - Graphical abstract: A new phase, Li{sub 2}<span class="hlt">Al</span>, has been discovered in the binary Li-<span class="hlt">Al</span> <span class="hlt">system</span>. The structure of orthorhombic Li{sub 2}<span class="hlt">Al</span> is closely related to that of the established monoclinic phase Li{sub 9}<span class="hlt">Al</span>{sub 4}.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.dtic.mil/docs/citations/ADA601698','DTIC-ST'); return false;" href="http://www.dtic.mil/docs/citations/ADA601698"><span>A <span class="hlt">Systemic</span> Assessment Model for <span class="hlt">Al</span>-Qaida’s Global Jihad</span></a></p> <p><a target="_blank" href="https://publicaccess.dtic.mil/psm/api/service/search/search">DTIC Science & Technology</a></p> <p></p> <p>2013-04-11</p> <p>infrastructure, boycotts of Western goods and services, and “ depriv [ing] the western crusader from stealing the Muslims’ oil which is being drained as the...strategy. The subsequent demonstration employs the latter approach, examining the <span class="hlt">systemic</span> impact of Operation IRAQI FREEDOM (OIF) on <span class="hlt">Al</span>-Qaida’s...Prevent exploitation of Muslim resources by the infidels. MoP: Do the infidels reap unfair benefits from Muslim oil production? MoP: Do the</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=19760050746&hterms=frictions+metal&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D40%26Ntt%3Dfrictions%2Bmetal','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=19760050746&hterms=frictions+metal&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D40%26Ntt%3Dfrictions%2Bmetal"><span>Effect of adsorbed films on friction of <span class="hlt">Al</span>2O3-metal <span class="hlt">systems</span></span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Pepper, S. V.</p> <p>1976-01-01</p> <p>The kinetic friction of polycrystalline <span class="hlt">Al</span>2O3 sliding on Cu, Ni, and Fe in ultrahigh vacuum was studied as a function of the surface chemistry of the metal. Clean metal surfaces were exposed to O2, Cl2, C2H4, and C2H3Cl, and the change in friction due to the adsorbed species was observed. Auger electron spectroscopy assessed the elemental composition of the metal surface. It was found that the <span class="hlt">systems</span> exposed to Cl2 exhibited low friction, interpreted as the van der Waals force between the <span class="hlt">Al</span>2O3 and metal chloride. The generation of metal oxide by oxygen exposures resulted in an increase in friction, interpreted as due to strong interfacial bonds established by reaction of metal oxide with <span class="hlt">Al</span>2O3 to form the complex oxide (spinel). The only effect of C2H4 was to increase the friction of the Fe <span class="hlt">system</span>, but C2H3Cl exposures decreases friction in both Ni and Fe <span class="hlt">systems</span>, indicating the dominance of the chlorine over the ethylene complex on the surface</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4825311','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4825311"><span>Clinical profile and treatment outcome of older (>75 years) patients with <span class="hlt">systemic</span> <span class="hlt">AL</span> amyloidosis</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Sachchithanantham, Sajitha; Offer, Mark; Venner, Christopher; Mahmood, Shameem A.; Foard, Darren; Rannigan, Lisa; Lane, Thirusha; Gillmore, Julian D.; Lachmann, Helen J.; Hawkins, Philip N.; Wechalekar, Ashutosh D.</p> <p>2015-01-01</p> <p><span class="hlt">Systemic</span> <span class="hlt">AL</span> amyloidosis, a disease with improving outcomes using novel therapies, is increasingly recognized in the elderly but treatment and outcomes have not been systematically studied in this group of patients in whom comorbidities and frailty may compound morbidity and mortality. We report the outcomes of 295 patients with <span class="hlt">systemic</span> <span class="hlt">AL</span> amyloidosis ≥75 years seen at the UK National Amyloidosis Centre from 2005–2012. The median age was 78.5 years. The median overall survival was 20 months. Two hundred and thirty-eight patients received chemotherapy and 57 elected for supportive care only (overall survival – 24 and 8.4 months, respectively). On intention-to-treat analysis, 44% achieved a hematologic response including a very good partial response or better in 23%. The median overall survival was 6.2 years in patients achieving very good partial response or better at the 6-month landmark analysis and 1.5 years in non-responders. Factors independently indicating a poor prognosis were: cardiac involvement, performance status ≥2; systolic blood pressure <100 mmHg and, on landmark analysis, achieving less than a very good partial response. Treatment of <span class="hlt">systemic</span> <span class="hlt">AL</span> amyloidosis in the elderly is challenging. Deep clonal responses are associated with excellent survival and organ responses. Achieving a response to the first-line regimen appears particularly important as outcomes of non-responders are similar to those of untreated patients. Prospective trials with lower toxicity, outpatient treatment regimens are needed. PMID:26294730</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25488034','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25488034"><span>Post-transplantation <span class="hlt">primary</span> central nervous <span class="hlt">system</span> lymphoma in a patient with <span class="hlt">systemic</span> lupus erythematosus and prolonged use of immunosuppressant.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Tse, Teresa P K; Chan, Allan N L; Chan, Tony K T; Po, Y C</p> <p>2014-12-01</p> <p>Post-transplantation <span class="hlt">primary</span> central nervous <span class="hlt">system</span> lymphoma is an uncommon and fatal post-transplant lymphoproliferative disorder. Such lymphomas have been described in only a few case series in the literature. The incidence of this condition is rising with improved survival after organ transplantation. A case of post-transplantation <span class="hlt">primary</span> central nervous <span class="hlt">system</span> lymphoma in a young Chinese woman with <span class="hlt">systemic</span> lupus erythematosus is described here. She presented with right-sided weakness and memory loss after tooth extraction 2 weeks before admission. Contrast computed tomography of the brain demonstrated a contrast rim-enhancing lesion over the left frontal lobe. With a history of recent dental procedure, long-term immunosuppressive therapy and computed tomography findings, cerebral abscess was highly suspected. Emergency operation was performed. Histopathology showed post-transplantation <span class="hlt">primary</span> central nervous <span class="hlt">system</span> lymphoma, with cells positive for B-cell marker CD20. Immunosuppressant was stopped and she was treated with radiotherapy and rituximab (anti-CD20 monoclonal antibody). She remained disease-free at 16 months. Post-transplantation <span class="hlt">primary</span> central nervous <span class="hlt">system</span> lymphoma is rare with variable presentation and radiological features. We believe rituximab may have a role in the treatment of such lymphomas.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/scitech/biblio/5566381','SCIGOV-STC'); return false;" href="https://www.osti.gov/scitech/biblio/5566381"><span><span class="hlt">Primary</span> lymphomas of the central nervous <span class="hlt">system</span>: patterns of failure and factors that influence survival</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Loeffler, J.S.; Ervin, T.J.; Mauch, P.; Skarin, A.; Weinstein, H.J.; Canellos, G.; Cassady, J.R.</p> <p>1985-04-01</p> <p><span class="hlt">Primary</span> lymphomas of the CNS are rare tumors accounting for less than 2% of all extranodal non-Hodgkin's lymphomas. The treatment for this disease has been disappointing. Radiation therapy and surgery have produced consistently poor control of this disease, with a median survival of 15 months. A review of ten cases of <span class="hlt">primary</span> lymphoma of the CNS treated at the Joint Center for Radiation Therapy or Dana-Farber Cancer Institute (Boston) from 1968 to 1981 is presented. All patients had biopsy- proven CNS lymphomas without <span class="hlt">systemic</span> disease at presentation. In this series, control of CNS lymphoma was seen only in patients receiving craniospinal radiation or CNS-penetrating chemotherapy.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/15366623','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/15366623"><span>Micro-tensile bond strength of adhesive <span class="hlt">systems</span> applied on occlusal <span class="hlt">primary</span> enamel.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Ramires-Romito, Ana Cláudia; Reis, Alessandra; Loguercio, Alessandro Dourado; de Góes, Mario Fernando; Grande, Rosa Helena Miranda</p> <p>2004-01-01</p> <p>The aim of this study was to evaluate the micro-tensile bond strength of adhesive <span class="hlt">systems</span> (OptiBond Solo, Kerr; Prime & Bond NT, Dentsply) on occlusal surface of <span class="hlt">primary</span> molars. The adhesives were tested under manufacturers' specifications and after contamination of the bonding site with saliva. Hourglass cylindrical-shaped samples were obtained and subjected to a tensile force. No significant difference was observed among the groups. OptiBond Solo and Prime & Bond NT showed similar values of bond strengths when applied on occlusal enamel of <span class="hlt">primary</span> molar under either saliva contamination or not.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/22085327','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/22085327"><span>Health <span class="hlt">system</span> factors affecting communication with pediatricians: gendered work culture in <span class="hlt">primary</span> care.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Lynch, Sean</p> <p>2011-01-01</p> <p>This qualitative study examined the roles that practice setting, education level, and gender may play in social workers' communication satisfaction with pediatricians. Taking an ethnographic approach, the researcher interviewed social workers and pediatricians who worked together to provide mental health services in <span class="hlt">primary</span> care. The results suggested that gender at the health <span class="hlt">system</span> level may be an issue and that gendered work culture in <span class="hlt">primary</span> care was a factor in communication. In particular, reimbursement, an aspect of the gendered work culture, was a substantial communication barrier, and the implications for Medicaid billing are discussed.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/24020596','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/24020596"><span>Patient-centered <span class="hlt">primary</span> health care: synergy potential for health <span class="hlt">systems</span> strengthening.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Stender, S C; Christensen, A</p> <p>2013-10-01</p> <p>The ultimate goal of government health <span class="hlt">systems</span> is to provide highly effective equitable services that save lives and reduce morbidity and mortality. The pressure to conform to duplicative global and donor initiatives compounds existing challenges to health <span class="hlt">systems</span> strengthening such as shortages of human resources for health, weak supply chains, inadequate laboratory services and parallel data management <span class="hlt">systems</span>. This article illustrates how <span class="hlt">primary</span> health care, as the point of entry into the health care <span class="hlt">system</span> for the majority of individuals in sub-Saharan Africa, should be strengthened to ensure that individuals and their communities receive essential, holistic care.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2006PSSAR.203.2581J','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2006PSSAR.203.2581J"><span>Real-time investigations of selenization reactions in the <span class="hlt">system</span> Cu-In-<span class="hlt">Al</span>-Se</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Jost, Stefan; Hergert, Frank; Hock, Rainer; Purwins, Michael; Enderle, Ralph</p> <p>2006-09-01</p> <p>In this article we present results of a detailed study of selenization reactions in the quaternary <span class="hlt">system</span> Cu-In-<span class="hlt">Al</span>-Se and of the binary subsystem aluminum-selenium. The investigation of solid-state reactions involved in the formation of the compound semiconductor Cu(In,<span class="hlt">Al</span>)Se2 was performed using real-time X-ray diffraction (XRD) with a time resolution of 22.5 s while annealing an elemental layer stack of the metals covered with selenium. A temperature-resolved phase analysis shows that the formation of the semiconductor takes place via metal-selenides. Ex-situ XRD measurements of the processed thin films show a phase segregation concerning the aluminum content of the formed chalcopyrite. Subsequent Rietveld-refinement of real-time measurements reveals a formation reaction of the quaternary semiconductor Cu(In,<span class="hlt">Al</span>)Se2 from the -In2Se3 related crystal structure of (<span class="hlt">Al</span>,In)2Se3 and Cu2Se as educts.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016JAP...120t5304L','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016JAP...120t5304L"><span>Structural and thermoelectric properties of SiGe/<span class="hlt">Al</span> multilayer <span class="hlt">systems</span> during metal induced crystallization</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Lindorf, M.; Rohrmann, H.; Span, G.; Raoux, S.; Jordan-Sweet, J.; Albrecht, M.</p> <p>2016-11-01</p> <p>While the process of metal induced crystallization (MIC) is widely used in the fabrication of thin film electronic devices, its application to the field of thermoelectrics is fairly new. Especially, its implementation in the field of the classic thermoelectric material SiGe could lead to a low cost approach by combining the benefits of low thermal budget, self-doping, and thin film and sputter deposition compatibility. In this work, samples consisting of SiGe/<span class="hlt">Al</span> multilayers deposited on aluminum oxide based substrates have been prepared. Special emphasis was put on the ratio of <span class="hlt">Al</span> to SiGe and the resulting changes in transport properties during annealing. On one hand, a certain amount of <span class="hlt">Al</span> is needed to ensure a complete MIC process for the SiGe, but on the other hand, an excess of <span class="hlt">Al</span> results in a metallic <span class="hlt">system</span> with low thermoelectric efficiency. In-situ characterization during annealing of the samples was carried out via x-ray diffraction, electrical resistivity, and Seebeck measurements.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/12114137','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/12114137"><span>Development of a handheld computer documentation <span class="hlt">system</span> to enhance an integrated <span class="hlt">primary</span> care clerkship.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Pipas, Catherine F; Carney, Patricia A; Eliassen, M Scottie; Mengshol, Sarah C; Fall, Leslie H; Olson, Ardis L; Schifferdecker, Karen E; Russell, Margaret T; Peltier, Deborah A; Nierenberg, David W</p> <p>2002-07-01</p> <p>Documentation <span class="hlt">systems</span> are used by medical schools and residency programs to record the clinical experiences of their learners. The authors developed a <span class="hlt">system</span> for their school's (Dartmouth's) multidisciplinary <span class="hlt">primary</span> care clerkship (family medicine, internal medicine, pediatrics) that documents students' clinical and educational experiences and provides feedback designed to enhance clinical training utilizing a timely data-reporting <span class="hlt">system</span>. The five critical components of the <span class="hlt">system</span> are (1) a valid, reliable and feasible data-collection instrument; (2) orientation of and ongoing support for student and faculty users; (3) generation and distribution of timely feedback reports to students, preceptors, and clerkship directors; (4) adequate financial and technical support; and (5) a database design that allows for overall evaluation of educational outcomes. The <span class="hlt">system</span>, whose development began in 1997, generated and distributed approximately 150 peer-comparison reports of clinical teaching experiences to students, preceptors, and course directors during 2001, in formats that are easy to interpret and use to individualize learning. The authors present report formats and annual cost estimate comparisons of paper- and computer-based <span class="hlt">system</span> development and maintenance, which range from $35,935 to $53,780 for the paper-based <span class="hlt">system</span> and from $46,820 to $109,308 for the computer-based <span class="hlt">system</span>. They mention ongoing challenges in components of the <span class="hlt">system</span>. They conclude that a comprehensive documentation and feedback <span class="hlt">system</span> provides an essential infrastructure for the evaluation and enhancement of community-based teaching and learning in <span class="hlt">primary</span> care ambulatory clerkships, whether separate or integrated.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26594800','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26594800"><span>A PCA3 gene-based transcriptional amplification <span class="hlt">system</span> targeting <span class="hlt">primary</span> prostate cancer.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Neveu, Bertrand; Jain, Pallavi; Têtu, Bernard; Wu, Lily; Fradet, Yves; Pouliot, Frédéric</p> <p>2016-01-12</p> <p>Targeting specifically <span class="hlt">primary</span> prostate cancer (PCa) cells for immune therapy, gene therapy or molecular imaging is of high importance. The PCA3 long non-coding RNA is a unique PCa biomarker and oncogene that has been widely studied. This gene has been mainly exploited as an accurate diagnostic urine biomarker for PCa detection. In this study, the PCA3 promoter was introduced into a new transcriptional amplification <span class="hlt">system</span> named the 3-Step Transcriptional Amplification <span class="hlt">System</span> (PCA3-3STA) and cloned into type 5 adenovirus. PCA3-3STA activity was highly specific for PCa cells, ranging between 98.7- and 108.0-fold higher than that for benign <span class="hlt">primary</span> prostate epithelial or non-PCa cells, respectively. In human PCa xenografts, PCA3-3STA displayed robust bioluminescent signals at levels that are sufficient to translate to positron emission tomography (PET)-based reporter imaging. Remarkably, when freshly isolated benign or cancerous prostate biopsies were infected with PCA3-3STA, the optical signal produced from <span class="hlt">primary</span> PCa biopsies was significantly higher than from benign prostate biopsies (4.4-fold, p < 0.0001). PCA3-3STA therefore represents a PCa-specific expression <span class="hlt">system</span> with the potential to target, with high accuracy, <span class="hlt">primary</span> or metastatic PCa epithelial cells for imaging, vaccines, or gene therapy.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2328061','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2328061"><span>Perceived role of <span class="hlt">primary</span> care physicians in Nova Scotia's reformed health care <span class="hlt">system</span>. Qualitative study.</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Sangster, L. M.; McGuire, D. P.</p> <p>1999-01-01</p> <p>OBJECTIVE: To determine <span class="hlt">primary</span> care physicians' perceptions of their role in a reformed health <span class="hlt">system</span>. DESIGN: Qualitative study using in-depth interviews. SETTING: Province of Nova Scotia. PARTICIPANTS: Purposefully selected sample of 14 practising <span class="hlt">primary</span> care physicians. MAIN OUTCOME FINDINGS: Participants identified seven aspects of their role: primarily, diagnosis and treatment of patient's medical problems; then coordination, counseling, education, advocacy, disease prevention, and gatekeeping. The range of activities and degree of responsibility assumed by participants, however, varied. Factors affecting role perception fell into three categories: philosophical view of health and medicine, willingness to collaborate, and practical realities. Participants differed in their understanding of <span class="hlt">primary</span> health care and their overall vision of the health <span class="hlt">system</span>. Remuneration policies and concerns about sharing accountability were factors preventing an integrated, collaborative approach to care. Personal, patient, and structural realities also limited physicians' roles. CONCLUSIONS: This sample of <span class="hlt">primary</span> care physicians had diverse perceptions of their role. Results of this study could provide information for identifying issues that need to be addressed to facilitate changes taking place in the health care <span class="hlt">system</span>. PMID:10889862</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/21604505','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/21604505"><span>[The <span class="hlt">primary</span> research and development of software oversampling mapping <span class="hlt">system</span> for electrocardiogram].</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Zhou, Yu; Ren, Jie</p> <p>2011-04-01</p> <p>We put forward a new concept of software oversampling mapping <span class="hlt">system</span> for electrocardiogram (ECG) to assist the research of the ECG inverse problem to improve the generality of mapping <span class="hlt">system</span> and the quality of mapping signals. We then developed a conceptual <span class="hlt">system</span> based on the traditional ECG detecting circuit, Labview and DAQ card produced by National Instruments, and at the same time combined the newly-developed oversampling method into the <span class="hlt">system</span>. The results indicated that the <span class="hlt">system</span> could map ECG signals accurately and the quality of the signals was good. The improvement of hardware and enhancement of software made the <span class="hlt">system</span> suitable for mapping in different situations. So the <span class="hlt">primary</span> development of the software for oversampling mapping <span class="hlt">system</span> was successful and further research and development can make the <span class="hlt">system</span> a powerful tool for researching ECG inverse problem.</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_10");'>10</a></li> <li><a href="#" onclick='return showDiv("page_11");'>11</a></li> <li class="active"><span>12</span></li> <li><a href="#" onclick='return showDiv("page_13");'>13</a></li> <li><a href="#" onclick='return showDiv("page_14");'>14</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_12 --> <div id="page_13" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_11");'>11</a></li> <li><a href="#" onclick='return showDiv("page_12");'>12</a></li> <li class="active"><span>13</span></li> <li><a href="#" onclick='return showDiv("page_14");'>14</a></li> <li><a href="#" onclick='return showDiv("page_15");'>15</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="241"> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/scitech/biblio/22255054','SCIGOV-STC'); return false;" href="https://www.osti.gov/scitech/biblio/22255054"><span>Hydrogen migration dynamics in hydrated <span class="hlt">Al</span> clusters: The <span class="hlt">Al</span>{sub 17}{sup (−)}·H{sub 2}O <span class="hlt">system</span> as an example</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Álvarez-Barcia, S.; Flores, J. R.</p> <p>2014-02-28</p> <p>The <span class="hlt">Al</span>{sub m}{sup (−)}·(H{sub 2}O){sub n} <span class="hlt">systems</span> are known to undergo water splitting processes in the gas phase giving H{sub k}<span class="hlt">Al</span>{sub m}(OH){sub k}{sup (−)}·(H{sub 2}O){sub n−k} <span class="hlt">systems</span>, which can generate H{sub 2}. The migration of H atoms from one <span class="hlt">Al</span> atom to another on the cluster's surface is of critical importance to the mechanism of the complete H{sub 2} production process. We have applied a combination of Molecular Dynamics and Rice-Ramsperger-Kassel-Marcus theory including tunneling effects to study the gas-phase evolution of HAl{sub 17}(OH){sup (−)}, which can be considered a model <span class="hlt">system</span>. First, we have performed an extensive search for local minima and the connecting saddle points using a density functional theory method. It is found that in the water-splitting process <span class="hlt">Al</span>{sub 17}{sup (−)}·(H{sub 2}O) → HAl{sub 17}(OH){sup (−)}, the H atom which bonds to the <span class="hlt">Al</span> cluster losses rather quickly its excess energy, which is easily “absorbed” by the cluster because of its flexibility. This fact ultimately determines that long-range hydrogen migration is not a very fast process and that, probably, tunneling only plays a secondary role in the migration dynamics, at least for moderate energies. Reduction of the total energy results in the process being very much slowed down. The consequences on the possible mechanisms of H{sub 2} generation from the interaction of <span class="hlt">Al</span> clusters and water molecules are discussed.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2011ApPhL..98i1905M','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2011ApPhL..98i1905M"><span>Influence of sample processing parameters on thermal boundary conductance value in an <span class="hlt">Al/Al</span>N <span class="hlt">system</span></span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Monachon, Christian; Hojeij, Mohamad; Weber, Ludger</p> <p>2011-02-01</p> <p>The influence of sample processing parameters on the thermal boundary conductance (TBC) between aluminum and aluminum nitride has been investigated by transient thermoreflectance. An evaporated <span class="hlt">Al</span> layer on the polished substrate yielded a TBC at ambient of roughly 47 MW m-2 K-1. The largest improvement (by a factor of 5) was obtained by plasma-etching of the substrate and subsequent evaporation of the metal layer. Electron microscopy suggests that the differences in TBC were mainly due to the (partial) elimination of the native oxide layer on the substrate. The importance of an adequate model for data extraction on measured TBC is highlighted.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/24301716','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/24301716"><span>Payment <span class="hlt">systems</span> and incentives in <span class="hlt">primary</span> care: implications of recent reforms in Estonia and Romania.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Dan, Sorin; Savi, Riin</p> <p>2015-01-01</p> <p>Since the early 1990s, major reform in healthcare has been adopted in former communist countries in Central and Eastern Europe. More than 20 years after, reform in healthcare still draws much interest from policy makers and academics alike. One of the dynamic components of reform has been the reform of payment <span class="hlt">systems</span> in <span class="hlt">primary</span> care. This article looks at recent developments in payment <span class="hlt">systems</span> and financial incentives in Estonia and Romania. We conclude that finding the appropriate mix in paying and incentivizing <span class="hlt">primary</span> care providers in a transitional context is no easy solution for healthcare policy makers who need to carefully weigh in the advantages and inherent problems of various payment arrangements. In a transitional, rapidly changing healthcare <span class="hlt">system</span> and society, and a context of financial stringency, the theoretical effects of payment mechanisms may be more difficult to predict and manage than it is expected.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5090079','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5090079"><span>Randomized Clinical Trial of Composite Restorations in <span class="hlt">Primary</span> Teeth: Effect of Adhesive <span class="hlt">System</span> after Three Years</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Donmez, Secil Bektaş; Uysal, Serdar; Ozdemir, Pinar; Tekcicek, Meryem; Zimmerli, Brigitte; Lussi, Adrian</p> <p>2016-01-01</p> <p>The purpose of this study was to assess the clinical performance of composite restorations placed with different adhesive <span class="hlt">systems</span> in <span class="hlt">primary</span> teeth. In 32 patients, 128 composite restorations were placed using a split-mouth design as follows (4 groups/patient): three-step etch-and-rinse (Group 1), two-step etch-and-rinse (Group 2), two-step self-etch (Group 3), and one-step self-etch (Group 4). The restorations were clinically evaluated at baseline and at 6, 18, and 36 months according to the FDI criteria. There was no significant difference between the adhesive <span class="hlt">systems</span> in retention of the restorations (p > 0.05). Over time, there was a statistically significant decrease in marginal adaptation in all groups, whereas surface and marginal staining significantly increased in Groups 3 and 4 (p < 0.05). The etch-and-rinse adhesive <span class="hlt">systems</span> resulted in better marginal adaptation than the self-etch adhesive <span class="hlt">systems</span> (p < 0.05). It was concluded that preetching of the <span class="hlt">primary</span> enamel might help improve the clinical performance of the self-etch adhesive <span class="hlt">systems</span> in <span class="hlt">primary</span> teeth. PMID:27833917</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2013CSR....52...62L','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2013CSR....52...62L"><span><span class="hlt">Primary</span> production and sinking export during fall in the Hudson Bay <span class="hlt">system</span>, Canada</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Lapoussière, Amandine; Michel, Christine; Gosselin, Michel; Poulin, Michel; Martin, Johannie; Tremblay, Jean-Éric</p> <p>2013-01-01</p> <p><span class="hlt">Primary</span> production and organic material sinking export were investigated in the Hudson Bay <span class="hlt">system</span> (i.e., Hudson Bay, Hudson Strait and Foxe Basin) under ice-free conditions during early fall 2005, using the 14C-uptake method and short-term free-drifting particle interceptor traps deployed below the euphotic zone at 50 m. Principal component analysis revealed spatial patterns of <span class="hlt">primary</span> production and chlorophyll a (chl a) biomass in the euphotic zone that were shaped by hydrographic conditions and nutrient concentrations linked to freshwater/seawater influence. <span class="hlt">Primary</span> production rates varied widely, from 70 to 435 mg C m-2 d-1, while the range of particulate organic carbon (POC) sinking fluxes was narrow, from 50 to 77 mg C m-2 d-1. Consequently, high ratios of POC sinking export to <span class="hlt">primary</span> production (i.e., export ratios; range of 0.38-0.69) were observed at stations where <span class="hlt">primary</span> production was low and dominated by small cells, and where heterotrophic protist dominated in biomass. These results show that at short temporal scales neither protist community structure nor biomass or production rates could be used to predict the magnitude of POC sinking export from the euphotic zone.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4410115','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4410115"><span>Does a quality management <span class="hlt">system</span> improve quality in <span class="hlt">primary</span> care practices in Switzerland? A longitudinal study</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Goetz, Katja; Hess, Sigrid; Jossen, Marianne; Huber, Felix; Rosemann, Thomas; Brodowski, Marc; Künzi, Beat; Szecsenyi, Joachim</p> <p>2015-01-01</p> <p>Objectives To examine the effectiveness of the quality management programme—European Practice Assessment—in <span class="hlt">primary</span> care in Switzerland. Design Longitudinal study with three points of measurement. Setting <span class="hlt">Primary</span> care practices in Switzerland. Participants In total, 45 of 91 <span class="hlt">primary</span> care practices completed European Practice Assessment three times. Outcomes The interval between each assessment was around 36 months. A variance analyses for repeated measurements were performed for all 129 quality indicators from the domains: ‘infrastructure’, ‘information’, ‘finance’, and ‘quality and safety’ to examine changes over time. Results Significant improvements were found in three of four domains: ‘quality and safety’ (F=22.81, p<0.01), ‘information’ (F=27.901, p<0.01) and ‘finance’ (F=4.073, p<0.02). The 129 quality indicators showed a significant improvement within the three points of measurement (F=33.864, p<0.01). Conclusions The European Practice Assessment for <span class="hlt">primary</span> care practices thus provides a functioning quality management programme, focusing on the sustainable improvement of structural and organisational aspects to promote high quality of <span class="hlt">primary</span> care. The implementation of a quality management <span class="hlt">system</span> which also includes a continuous improvement process would give added value to provide good care. PMID:25900466</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/scitech/biblio/1349018','SCIGOV-STC'); return false;" href="https://www.osti.gov/scitech/biblio/1349018"><span>Investigating Power <span class="hlt">System</span> <span class="hlt">Primary</span> and Secondary Reserve Interaction under High Wind Penetration Using Frequency Response Model</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Tan, Jin; Zhang, Yingchen; Krad, Ibrahim; Gevorgian, Vahan; Ela, Erik</p> <p>2015-10-12</p> <p>Power <span class="hlt">system</span> frequency needs to be maintained close to its nominal value at all times to avoid machine damage, under-frequency load-shedding and even blackouts. Adequate <span class="hlt">primary</span> frequency response and secondary frequency response are the <span class="hlt">primary</span> forces to correct an energy imbalance at the second to minute level. As wind energy becomes a larger portion of the world's energy portfolio, there are greater oppotunities for wind to provide frequency response services. This paper addresses one area of frequency control that has been missing in previous work - the reliabilty impacts and interactions between <span class="hlt">primary</span> and secondary frequency control. The lack of a commercially available tools to simulate the interaction of these two responses has limited the energy industry's understanding of when the depletion of <span class="hlt">primary</span> control reserve will impact the performance of secondary conrol response or vice versa. To investigate this issue, in this paper we develop a multi-area frequency response integration model with combined <span class="hlt">primary</span> and secondary frequency control capabilities.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2014SPIE.8973E..0IK','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2014SPIE.8973E..0IK"><span>Optimal microelectromechanical <span class="hlt">systems</span> (MEMS) device for achieving high pyroelectric response of <span class="hlt">Al</span>N</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Kebede, Bemnnet; Coutu, Ronald A.; Starman, LaVern</p> <p>2014-03-01</p> <p>This paper discusses research being conducted on aluminum nitride (<span class="hlt">Al</span>N) as a pyroelectric material for use in detecting applications. <span class="hlt">Al</span>N is being investigated because of its high pyroelectric coefficient, thermal stability, and high Curie temperature. In order to determine suitability of the pyroelectric properties of <span class="hlt">Al</span>N for use as a detector, testing of several devices was conducted. These devices were fabricated using microelectromechanical <span class="hlt">systems</span> (MEMS) fabrication processes; the devices were also designed to allow for voltage and current measurements. The deposited <span class="hlt">Al</span>N films used were 150 nm - 300 nm in thickness. Thin-films were used to rapidly increase the temperature response after the thermal stimulus was applied to the pyroelectric material. This is important because the pyroelectric effect is directly proportional to the rate of temperature change. The design used was a face-electrode bridge that provides thermal isolation which minimizes heat loss to the substrate, thereby increasing operation frequency of the pyroelectric device. A thermal stimulus was applied to the pyroelectric material and the response was measured across the electrodes. A thermal imaging camera was used to monitor the changes in temperature. Throughout the testing process, the annealing temperatures, type of layers, and thicknesses were also varied. These changes resulted in improved MEMS designs, which were fabricated to obtain an optimal design configuration for achieving a high pyroelectric response. A pyroelectric voltage response of 38.9 mVp-p was measured without filtering, 12.45 mVp-p was measured in the infrared (IR) region using a Si filter, and 6.38 mVp-p was measured in the short wavelength IR region using a long pass filter. The results showed that <span class="hlt">Al</span>N's pyroelectric properties can be used in detecting applications.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2012PhPro..39..382S','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2012PhPro..39..382S"><span>Direct Metal Deposition of Functional Graded Structures in Ti- <span class="hlt">Al</span> <span class="hlt">System</span></span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Shishkovsky, I.; Missemer, F.; Smurov, I.</p> <p></p> <p>A direct laser metal deposition (DLMD) technology with co-axial powder injection is used to fabricate a complex functional graded structure (FGS) fabrication. The aim of the study is to demonstrate the possibility to produce intermetallic phases in the Ti-<span class="hlt">Al</span> powder <span class="hlt">systems</span> in the course of a single-step DMD process. Besides, relationships between the main laser cladding parameters and the intermetallic phase structures of the built-up objects have been studied. In our research we applied the optical microscopy, X-ray analysis, microhardness measurement and SEM with EDX analysis of the laser-fabricated intermetallics. The discussion of the mechanisms of Ti x <span class="hlt">Al</span> y (x,y = 1.3) intermetallic transformations in exothermal reactions is also offered in the report.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/scitech/biblio/22111950','SCIGOV-STC'); return false;" href="https://www.osti.gov/scitech/biblio/22111950"><span>Elastic scattering measurements for {sup 7}Be+{sup 27}<span class="hlt">Al</span> <span class="hlt">system</span> at RIBRAS facility</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Morcelle, V.; Lichtenthaeler, R.; Morais, M. C.; Lepine-Szily, A.; Guimaraes, V.; Faria, P. N. de; Gasques, L.; Pires, K. C. C.; Condori, R. P.; Gomes, P. R. S.; Lubian, J.; Mendes, D. R. Jr.; Barioni, A.; Shorto, J. M. B.; Zamora, J. C.</p> <p>2013-05-06</p> <p>Elastic scattering angular distribution measurements of {sup 7}Be+{sup 27}<span class="hlt">Al</span> <span class="hlt">system</span> were performed at the laboratory energy of 15.6 MeV. The {sup 7}Be secondary beam was produced by the proton transfer reaction {sup 3}He({sup 6}Li,{sup 7}Be) and impinged on {sup 27}<span class="hlt">Al</span> and {sup 197}Au targets, using the Radioactive Ion Beam (RIB) facility, RIBRAS. The elastic angular distribution was obtained within the angular range of 15{sup 0} - 80{sup 0} at the center of mass frame. Optical model calculations have been performed using the Woods- Saxon form factors and the Sao Paulo potential to fit the experimental data. The total reaction cross section was derived.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/scitech/biblio/1327114','SCIGOV-STC'); return false;" href="https://www.osti.gov/scitech/biblio/1327114"><span>FORMATION MECHANISM FOR THE NANOSCALE AMORPHOUS INTERFACE IN PULSE-WELDED <span class="hlt">AL</span>/FE BIMETALLIC <span class="hlt">SYSTEM</span></span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Li, Jingjing; Yu, Qian; Zhang, Zijiao; Xu, Wei; Sun, Xin</p> <p>2016-05-20</p> <p>Pulse or impact welding traditionally has been referred to as “solid-state” welding. By integrating advanced interface characterizations and diffusion calculations, we report that the nanoscale amorphous interface in the pulse-welded <span class="hlt">Al</span>/Fe bimetallic <span class="hlt">system</span> is formed by rapid heating and melting of a thin <span class="hlt">Al</span> layer at the interface, diffusion of iron atoms in the liquid aluminum, and subsequent rapid quenching with diffused iron atoms in solution. This finding challenges the commonly held belief regarding the solid-state nature of the impact-based welding process for dissimilar metals. Elongated ultra-fine grains with high dislocation density and ultra-fine equiaxed grains also are observed in the weld interface vicinity on the steel and aluminum sides, respectively, which further confirms that melting and the resulted recrystallization occurred on the aluminum side of the interface.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017MSHT...58..515K','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017MSHT...58..515K"><span>Strength of "Light" Ferritic and Austenitic Steels Based on the Fe - Mn - <span class="hlt">Al</span> - C <span class="hlt">System</span></span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Kaputkina, L. M.; Svyazhin, A. G.; Smarygina, I. V.; Kindop, V. E.</p> <p>2017-01-01</p> <p>The phase composition, the hardness, the mechanical properties at room temperature, and the resistance to hot (950 - 1000°C) and warm (550°C) deformation are studied for cast deformable "light" ferritic and austenitic steels of the Fe - (12 - 25)% Mn - (0 - 15)% <span class="hlt">Al</span> - (0 - 2)% C <span class="hlt">system</span> alloyed additionally with about 5% Ni. The high-aluminum high-manganese low-carbon and carbonless ferritic steels at a temperature of about 0.5 T melt have a specific strength close to that of the austenitic steels and may be used as weldable scale-resistant and wear-resistant materials. The high-carbon Fe - (20 - 24)% Mn - (5 - 9)% <span class="hlt">Al</span> - 5% Ni - 1.5% C austenitic steels may be applied as light high-strength materials operating at cryogenic temperatures after a solution treatment and as scale- and heat-resistant materials in an aged condition.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016ApPhL.108t1606L','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016ApPhL.108t1606L"><span>Formation mechanism for the nanoscale amorphous interface in pulse-welded <span class="hlt">Al</span>/Fe bimetallic <span class="hlt">systems</span></span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Li, Jingjing; Yu, Qian; Zhang, Zijiao; Xu, Wei; Sun, Xin</p> <p>2016-05-01</p> <p>Pulse or impact welding traditionally has been referred to as "solid-state" welding. By integrating advanced interface characterizations and diffusion calculations, we report that the nanoscale amorphous interface in the pulse-welded <span class="hlt">Al</span>/Fe bimetallic <span class="hlt">system</span> is formed by rapid heating and melting of a thin <span class="hlt">Al</span> layer at the interface, diffusion of iron atoms in the liquid aluminum, and subsequent rapid quenching with diffused iron atoms in solution. This finding challenges the commonly held belief regarding the solid-state nature of the impact-based welding process for dissimilar metals. Elongated ultra-fine grains with high dislocation density and ultra-fine equiaxed grains also are observed in the weld interface vicinity on the steel and aluminum sides, respectively, which further confirms that melting and the subsequent recrystallization occurred on the aluminum side of the interface.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016JSSCh.243..168M','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016JSSCh.243..168M"><span>Investigation of the phase relations in the U-<span class="hlt">Al</span>-Ge ternary <span class="hlt">system</span>: Influence of the <span class="hlt">Al</span>/Ge substitution on the properties of the intermediate phases</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Moussa, C.; El Sayah, Z.; Chajewski, G.; Berche, A.; Dorcet, V.; Pikul, A. P.; Pasturel, M.; Joanny, L.; Stepnik, B.; Tougait, O.</p> <p>2016-11-01</p> <p>The phase relations within the U-<span class="hlt">Al</span>-Ge ternary <span class="hlt">system</span> were studied for two isothermal sections, at 673 K for the whole Gibbs triangle and at 1173 K for the concentration range 25-100 at% U. The identification of the phases, their composition ranges and stability were determined by x-ray powder diffraction, scanning electron microscopy coupled to energy dispersive spectroscopy and differential thermal analysis. The tie-lines and the solubility domains were determined for the U-Ge and U-<span class="hlt">Al</span> binaries, the UAl3-UGe3 solid-solution and for the unique ternary intermediate phase U3<span class="hlt">Al</span>2-xGe3+x. The experimental isopleth section of the pseudo-binary UAl3-UGe3 reveals an isomorphous solid solution based on the Cu3Au-type below the solidus. The U3<span class="hlt">Al</span>2-xGe3+x solid solution extends for -0.1≤x≤1.35 and -0.2≤x≤1.5 at 673 K and 1173 K respectively. It crystallizes in the I-centered tetragonal symmetry. The reciprocal lattice of several compositions of the U3<span class="hlt">Al</span>2-xGe3+x solid solution was examined by electron diffraction at room temperature, revealing the presence of a c-glide plane. Their crystal structure was refined by single crystal x-ray diffraction suggesting an isomorphous solid solution best described with the non-centrosymmetric space group I4cm in the paramagnetic domain. The magnetic measurements confirm the ferromagnetic ordering of the solid solution U3<span class="hlt">Al</span>2-xGe3+x with an increase of Tc with the <span class="hlt">Al</span> content. The thermal variation of the specific heat bear out the magnetic transitions with some delocalized character of the uranium 5f electrons.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28382683','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28382683"><span>Increased Light-Use Efficiency Sustains Net <span class="hlt">Primary</span> Productivity of Shaded Coffee Plants In Agroforestry <span class="hlt">System</span>.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Charbonnier, Fabien; Roupsard, Olivier; le Maire, Guerric; Guillemot, Joannès; Casanoves, Fernando; Lacointe, André; Vaast, Philippe; Allinne, Clémentine; Audebert, Louise; Cambou, Aurélie; Clément-Vidal, Anne; Defrenet, Elsa; Duursma, Remko A; Jarri, Laura; Jourdan, Christophe; Khac, Emmanuelle; Leandro, Patricia; Medlyn, Belinda E; Saint-André, Laurent; Thaler, Philippe; Van den Meersche, Karel; Barquero Aguilar, Alejandra; Lehner, Peter; Dreyer, Erwin</p> <p>2017-04-06</p> <p>In agroforestry <span class="hlt">systems</span>, shade trees strongly affect the physiology of the undergrown crop. However, a major paradigm is that the reduction in absorbed photosynthetically active radiation is, to a certain extent, compensated by an increase in light-use efficiency, thereby reducing the difference in net <span class="hlt">primary</span> productivity between shaded and non-shaded plants. Due to the large spatial heterogeneity in agroforestry <span class="hlt">systems</span> and the lack of appropriate tools, the combined effects of such variables have seldom been analysed, even though they may help understand physiological processes underlying yield dynamics. In this study, we monitored net <span class="hlt">primary</span> productivity, during two years, on scales ranging from individual coffee plants to the entire plot. Absorbed radiation was mapped with a 3D-model (MAESPA). Light-use efficiency and net assimilation rate were derived for each coffee plant individually. We found that although irradiance was reduced by 60% below crowns of shade trees, coffee light-use efficiency increased by 50%, leaving net <span class="hlt">primary</span> productivity fairly stable across all shade levels. Variability of aboveground net <span class="hlt">primary</span> productivity of coffee plants was caused primarily by the age of the plants and by intraspecific competition among them (drivers usually overlooked in the agroforestry literature) rather than by the presence of shade trees.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27893519','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27893519"><span>Effects of Hospital <span class="hlt">Systems</span> on Medical Home Transformation in <span class="hlt">Primary</span> Care Residency Training Practices.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Knierim, Kyle; Hall, Tristen; Fernald, Douglas; Staff, Thomas J; Buscaj, Emilie; Allen, Jessica Cornett; Onysko, Mary; Dickinson, W Perry</p> <p>2016-11-23</p> <p>Most <span class="hlt">primary</span> care residency training practices have close financial and administrative relationships with teaching hospitals and health <span class="hlt">systems</span>. Many residency practices have begun integrating the core principles of the patient-centered medical home (PCMH) into clinical workflows and educational experiences. Little is known about how the relationships with hospitals and health <span class="hlt">systems</span> affect these transformation efforts. Data from the Colorado Residency PCMH Project were analyzed. Results show that teaching hospitals and health <span class="hlt">systems</span> have significant opportunities to influence residency practices' transformation, particularly in the areas of supporting team-based care, value-based payment reforms, and health information technology.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25591411','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25591411"><span><span class="hlt">Primary</span> health care and public health: foundations of universal health <span class="hlt">systems</span>.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>White, Franklin</p> <p>2015-01-01</p> <p>The aim of this review is to advocate for more integrated and universally accessible health <span class="hlt">systems</span>, built on a foundation of <span class="hlt">primary</span> health care and public health. The perspective outlined identified health <span class="hlt">systems</span> as the frame of reference, clarified terminology and examined complementary perspectives on health. It explored the prospects for universal and integrated health <span class="hlt">systems</span> from a global perspective, the role of healthy public policy in achieving population health and the value of the social-ecological model in guiding how best to align the components of an integrated health service. The importance of an ethical private sector in partnership with the public sector is recognized. Most health <span class="hlt">systems</span> around the world, still heavily focused on illness, are doing relatively little to optimize health and minimize illness burdens, especially for vulnerable groups. This failure to improve the underlying conditions for health is compounded by insufficient allocation of resources to address priority needs with equity (universality, accessibility and affordability). Finally, public health and <span class="hlt">primary</span> health care are the cornerstones of sustainable health <span class="hlt">systems</span>, and this should be reflected in the health policies and professional education <span class="hlt">systems</span> of all nations wishing to achieve a health <span class="hlt">system</span> that is effective, equitable, efficient and affordable.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/21273747','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/21273747"><span><span class="hlt">Primary</span> angiitis of the central nervous <span class="hlt">system</span> mimicking tumor-like lesion--case report.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Tanei, Takafumi; Nakahara, Norimoto; Takebayashi, Shigenori; Ito, Masafumi; Hashizume, Yoshio; Wakabayashi, Toshihiko</p> <p>2011-01-01</p> <p>A 60-year-old man presented with a rare case of <span class="hlt">primary</span> angiitis of the central nervous <span class="hlt">system</span> mimicking a tumor-like lesion and manifesting as slight disorientation, left hemiparesis, and motor aphasia. Computed tomography showed multiple low density lesions in the left frontal lobe, brain stem, and right parietal lobe. Magnetic resonance images revealed a slightly enhanced mass lesion in the right parietal lobe with surrounding brain edema. Serum, cerebrospinal fluid, and other image examinations did not show any abnormal findings, so surgical removal of the right parietal mass was performed. Histological examination revealed that the mass consisted of hemorrhagic infarction without cellular atypia. Proliferations of endothelial cells in small and medium arteries, and infiltration of macrophages in the perivascular space were detected in the infarction tissues. The histological diagnosis was <span class="hlt">primary</span> angiitis of the central nervous <span class="hlt">system</span>.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.osti.gov/scitech/servlets/purl/883120','SCIGOV-STC'); return false;" href="http://www.osti.gov/scitech/servlets/purl/883120"><span>INTEGRATED DRILLING <span class="hlt">SYSTEM</span> USING MUD ACTUATED DOWN HOLE HAMMER AS <span class="hlt">PRIMARY</span> ENGINE</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>John V. Fernandez; David S. Pixton</p> <p>2005-12-01</p> <p>A history and project summary of the development of an integrated drilling <span class="hlt">system</span> using a mud-actuated down-hole hammer as its <span class="hlt">primary</span> engine are given. The summary includes laboratory test results, including atmospheric tests of component parts and simulated borehole tests of the hammer <span class="hlt">system</span>. Several remaining technical hurdles are enumerated. A brief explanation of commercialization potential is included. The <span class="hlt">primary</span> conclusion for this work is that a mud actuated hammer can yield substantial improvements to drilling rate in overbalanced, hard rock formations. A secondary conclusion is that the down-hole mud actuated hammer can serve to provide other useful down-hole functions including generation of high pressure mud jets, generation of seismic and sonic signals, and generation of diagnostic information based on hammer velocity profiles.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://hdl.handle.net/2060/19780016329','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/19780016329"><span><span class="hlt">Primary</span> reaction control <span class="hlt">system</span>/remote manipulator <span class="hlt">system</span> interaction with loaded arm. Space shuttle engineering and operations support</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Taylor, E. C.; Davis, J. D.</p> <p>1978-01-01</p> <p>A study of the interaction between the orbiter <span class="hlt">primary</span> reaction control <span class="hlt">system</span> (PRCS) and the remote manipulator <span class="hlt">system</span> (RMS) with a loaded arm is documented. This analysis was performed with the Payload Deployment and Retrieval <span class="hlt">Systems</span> Simulation (PDRSS) program with the passive arm bending option. The passive-arm model simulates the arm as massless elastic links with locked joints. The study was divided into two parts. The first part was the evaluation of the response of the arm to step inputs (i.e. constant jet torques) about each of the orbiter body axes. The second part of the study was the evaluation of the response of the arm to minimum impulse <span class="hlt">primary</span> RCS jet firings with both single pulse and pulse train inputs.</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_11");'>11</a></li> <li><a href="#" onclick='return showDiv("page_12");'>12</a></li> <li class="active"><span>13</span></li> <li><a href="#" onclick='return showDiv("page_14");'>14</a></li> <li><a href="#" onclick='return showDiv("page_15");'>15</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_13 --> <div id="page_14" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_12");'>12</a></li> <li><a href="#" onclick='return showDiv("page_13");'>13</a></li> <li class="active"><span>14</span></li> <li><a href="#" onclick='return showDiv("page_15");'>15</a></li> <li><a href="#" onclick='return showDiv("page_16");'>16</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="261"> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/15825280','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/15825280"><span>[Correction of spectral interferences by ICP-AES <span class="hlt">primary</span> expert <span class="hlt">system</span>].</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Ying, H; Yang, P; Wang, X; Huang, B</p> <p>1998-12-01</p> <p>A subpackage for spectral interference correction has been set up in ICP-AES <span class="hlt">primary</span> expert <span class="hlt">system</span>. Some numerical recipes have been applied in this subpackage, such as curve smoothing, derivative spectrum, FFT technique, spectral resolving etc. A comprehensive method for spectral interference correction is presented. All these numeric recipes have been tested with simulated data and also utilized in several typical examples of real spectra. Results are satisfactory.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/scitech/biblio/22391497','SCIGOV-STC'); return false;" href="https://www.osti.gov/scitech/biblio/22391497"><span>Analysis of N-16 concentration in <span class="hlt">primary</span> cooling <span class="hlt">system</span> of AP1000 power reactor</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Rohanda, Anis; Waris, Abdul</p> <p>2015-04-16</p> <p>Nitrogen-16 (N-16) is one of the radiation safety parameter on the <span class="hlt">primary</span> reactor <span class="hlt">system</span>. The activation product, N-16, is the predominant contributor to the activity in the reactor coolant <span class="hlt">system</span> during reactor operation. N-16 is activation product derived from activation of O-16 with fast neutron based on {sup 16}O(n,p){sup 16}N reaction. Thus study is needed and it performs to determine N-16 concentration in reactor coolant (<span class="hlt">primary</span> coolant) in supporting radiation safety. One of the way is using analytical methode based on activation and redecay princip to obtain N-16 concentration. The analysis was performed on the configuration basis and operational of Westinghouse AP1000 power reactor in several monitoring points at coolant reactor <span class="hlt">system</span>. The results of the calculation of N-16 concentration at the core outlet, reactor vessel outlet, pressurizer line, inlet and outlet of steam generators, <span class="hlt">primary</span> pumps, reactor vessels inlet and core inlet are: 281, 257, 255, 250, 145, 142, 129 and 112 µCi/gram respectively. The results of analysis compared with AP1000 design control document as standard values. The verification showed very high accuracy comparation between analytical results and standard values.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015AIPC.1656f0012R','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015AIPC.1656f0012R"><span>Analysis of N-16 concentration in <span class="hlt">primary</span> cooling <span class="hlt">system</span> of AP1000 power reactor</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Rohanda, Anis; Waris, Abdul</p> <p>2015-04-01</p> <p>Nitrogen-16 (N-16) is one of the radiation safety parameter on the <span class="hlt">primary</span> reactor <span class="hlt">system</span>. The activation product, N-16, is the predominant contributor to the activity in the reactor coolant <span class="hlt">system</span> during reactor operation. N-16 is activation product derived from activation of O-16 with fast neutron based on 16O(n,p)16N reaction. Thus study is needed and it performs to determine N-16 concentration in reactor coolant (<span class="hlt">primary</span> coolant) in supporting radiation safety. One of the way is using analytical methode based on activation and redecay princip to obtain N-16 concentration. The analysis was performed on the configuration basis and operational of Westinghouse AP1000 power reactor in several monitoring points at coolant reactor <span class="hlt">system</span>. The results of the calculation of N-16 concentration at the core outlet, reactor vessel outlet, pressurizer line, inlet and outlet of steam generators, <span class="hlt">primary</span> pumps, reactor vessels inlet and core inlet are: 281, 257, 255, 250, 145, 142, 129 and 112 µCi/gram respectively. The results of analysis compared with AP1000 design control document as standard values. The verification showed very high accuracy comparation between analytical results and standard values.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3715251','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3715251"><span>Deployment and Validation of a Smart <span class="hlt">System</span> for Screening of Language Disorders in <span class="hlt">Primary</span> Care</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Martín-Ruiz, María Luisa; Duboy, Miguel Ángel Valero; de la Cruz, Iván Pau</p> <p>2013-01-01</p> <p>Neuro-evolutive development from birth until the age of six years is a decisive factor in a child's quality of life. Early detection of development disorders in early childhood can facilitate necessary diagnosis and/or treatment. <span class="hlt">Primary</span>-care pediatricians play a key role in its detection as they can undertake the preventive and therapeutic actions requested to promote a child's optimal development. However, the lack of time and little specific knowledge at <span class="hlt">primary</span>-care avoid to applying continuous early-detection anomalies procedures. This research paper focuses on the deployment and evaluation of a smart <span class="hlt">system</span> that enhances the screening of language disorders in <span class="hlt">primary</span> care. Pediatricians get support to proceed with early referral of language disorders. The proposed model provides them with a decision-support tool for referral actions to trigger essential diagnostic and/or therapeutic actions for a comprehensive individual development. The research was conducted by starting from a sample of 60 cases of children with language disorders. Validation was carried out through two complementary steps: first, by including a team of seven experts from the fields of neonatology, pediatrics, neurology and language therapy, and, second, through the evaluation of 21 more previously diagnosed cases. The results obtained show that therapist positively accepted the <span class="hlt">system</span> proposal in 18 cases (86%) and suggested <span class="hlt">system</span> redesign for single referral to a speech therapist in three remaining cases. PMID:23752564</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/scitech/biblio/22342232','SCIGOV-STC'); return false;" href="https://www.osti.gov/scitech/biblio/22342232"><span><span class="hlt">AL</span> Cassiopeiae: An F-type contact binary <span class="hlt">system</span> with a cool stellar companion</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Qian, S.-B.; Zhou, X.; Zhu, L.-Y.; Zhao, E.-G.; Liao, W.-P.; Zola, S.; Leung, K.-C.</p> <p>2014-11-01</p> <p>According to the general catalog of variable stars, <span class="hlt">AL</span> Cas was classified as an EW-type eclipsing binary with a spectral type of B and an orbital period of P = 0.5005555 days. The first photometric light curves of the close binary in the B, V, R, and I bands are presented. New low-resolution spectra indicate that its spectral type is about F7 rather than B-type. A photometric analysis with the Wilson-Devinney method suggests that it is a contact binary (f = 39.3%) with a mass ratio of 0.61. Using 17 newly determined eclipse times together with those collected from the literature, we found that the observed–calculated (O – C) curve of <span class="hlt">AL</span> Cas shows a cyclic change with a period of 86.6 yr and an amplitude of 0.0181 days. The periodic variation was analyzed for the light-travel time effect via the presence of a third body. The mass of the third body was determined to be M {sub 3}sin i' = 0.29(± 0.05) M {sub ☉} when a total mass of 2.14 M {sub ☉} for <span class="hlt">AL</span> Cas is adopted. It is expected that the cool companion star may have played an important role in the origin and evolution of the <span class="hlt">system</span> by removing angular momentum from the central binary <span class="hlt">system</span> during early dynamical interaction and/or late dynamical evolution. This causes the original detached <span class="hlt">system</span> to have a low angular momentum and a short initial orbital period. Then it can evolve into the present contact configuration via a case A mass transfer.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=299062','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=299062"><span>Activated neu oncogene sequences in <span class="hlt">primary</span> tumors of the peripheral nervous <span class="hlt">system</span> induced in rats by transplacental exposure to ethylnitrosourea.</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Perantoni, A O; Rice, J M; Reed, C D; Watatani, M; Wenk, M L</p> <p>1987-01-01</p> <p>Neurogenic tumors were selectively induced in high incidence in F344 rats by a single transplacental exposure to the direct-acting alkylating agent N-ethyl-N-nitrosourea (EtNU). We prepared DNA for transfection of NIH 3T3 cells from <span class="hlt">primary</span> glial tumors of the brain and from schwannomas of the cranial and spinal nerves that developed in the transplacentally exposed offspring between 20 and 40 weeks after birth. DNA preparations from 6 of 13 schwannomas, but not from normal liver, kidney, or intestine of tumor-bearing rats, transformed NIH 3T3 cells. NIH 3T3 clones transformed by schwannoma DNA contained rat repetitive DNA sequences, and all isolates contained rat neu oncogene sequences. One schwannoma yielded a transformant with rat-specific sequences for both neu and N-ras. A point mutation in the transmembrane region of the putative protein product of neu was identified in all six transformants and in the <span class="hlt">primary</span> tumors from which they were derived as well as in 5 of 6 schwannomas tested that did not transform NIH 3T3 cells. Of 59 gliomas, only one yielded transforming DNA, and an activated N-ras oncogene was identified. The normal cellular neu sequence for the transmembrane region, but not the mutated sequence, was identified in DNA from all 11 gliomas surveyed by oligonucleotide hybridization. Activation of the neu oncogene, originally identified [Schechter, <span class="hlt">A.L</span>., Stern, D.F., Vaidyanathan, L., Decker, S.J., Drebin, J.A., Greene, M.I. & Weinberg, R.A. (1984) Nature (London) 312, 513-516] in cultured cell lines derived from EtNU-induced neurogenic tumors that by biochemical but not histologic criteria were thought to originate in the central nervous <span class="hlt">system</span> in BD-IX rats, appears specifically associated with tumors of the peripheral nervous <span class="hlt">system</span> in the F344 inbred strain. Images PMID:3476947</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.osti.gov/scitech/servlets/purl/67710','SCIGOV-STC'); return false;" href="http://www.osti.gov/scitech/servlets/purl/67710"><span>The amplitude and phase control of the <span class="hlt">ALS</span> Storage Ring RF <span class="hlt">System</span></span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Lo, C.C.; Taylor, B.; Baptiste, K.</p> <p>1995-03-01</p> <p>A 500MHz, 300KW Klystron power amplifier provides RF power to the <span class="hlt">ALS</span> Storage Ring. In order to accommodate the amplitude and phase changes during beam stacking and decay, which demand continuously varying power levels from the Klystron, four loops are used to keep the <span class="hlt">system</span> operating properly, with two of those loops dedicated to keeping the two cavity tuners on tune. Description of the control loops and their performance data will be given. Using the modulation anode of the Klystron in the amplitude loop will be discussed.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28032835','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28032835"><span>Activities and Attributes of Nurse Practitioner Leaders: Lessons from a <span class="hlt">Primary</span> Care <span class="hlt">System</span> Change.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>O'Rourke, Tammy; Higuchi, Kathryn Smith</p> <p>2016-01-01</p> <p>Nurse practitioners (NPs) are being encouraged to practice to the full extent of their skills, and they have a critical role to play in leading health <span class="hlt">system</span> reform. The evidence in support of NP-led initiatives is growing; however, in spite of the positive outcomes associated with these initiatives, considerable opposition to and debate about the potential for NPs to lead health <span class="hlt">system</span> change and interprofessional teams continues. To date, we know very little about NP leadership activities, particularly those activities that contribute to <span class="hlt">primary</span> care <span class="hlt">system</span> change, and there are very few examples of this type of leadership. The qualitative descriptive study here was part of a larger case study that examined stakeholder participation in a <span class="hlt">system</span> change led by NPs. The change involved the introduction of a new NP-led model of team-based <span class="hlt">primary</span> care delivery in Ontario, Canada. Data from participant interviews and public documents were analyzed to describe the activities and attributes (perseverance, risk-taking and effective communication) of two NP leaders who were the drivers of this change. Knowledge of these activities and attributes has the potential to inform NP leadership roles in health <span class="hlt">system</span> policy planning and implementation. However, to be able to provide effective leadership in <span class="hlt">system</span> change, NPs need access to educational content about public policy and opportunities to develop and practice the skills required to work with multiple stakeholders, including those who oppose change.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/scitech/biblio/186788','SCIGOV-STC'); return false;" href="https://www.osti.gov/scitech/biblio/186788"><span>Combustion synthesis of metal-matrix composites. Part 2: The Ti-Ti{sub x}<span class="hlt">Al</span>{sub y}-<span class="hlt">Al</span>{sub 2}O{sub 3} <span class="hlt">system</span></span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Kunrath, A.O.; Strohaecker, T.R.; Moore, J.J.</p> <p>1996-01-15</p> <p>The production of high performance materials (ceramics, intermetallics and composites) by combustion synthesis is receiving considerable attention since the process offers certain advantages with respect to simplicity and a relatively low energy requirement. The methods by which combustion synthesis (or SHS) can be used to produce metal matrix composites were outlined in an earlier paper. The use of excess liquid metal in the combustion synthesis reaction has already been successfully employed to achieve low porosity products. This metallic phase may be generated by an in-situ reduction of a metal oxide or by adding an excess of some metal to the reactants. Coupling a simultaneous consolidation (pressing) process with the SHS reaction has been found to produce dense bodies. This work discussed in this paper is concerned with the synthesis of a metallic/intermetallic matrix composite reaction <span class="hlt">system</span> which can be represented by equation. With this reaction, high volume fractions of metallic/intermetallic phases can be produced. The metal-matrix produced by this reaction is predominantly a mixture of Ti{sub 3}<span class="hlt">Al</span> + Ti as indicated in the appropriate area of the Ti-<span class="hlt">Al</span> phase diagram. Increasing x increases the volume fraction of Ti. Ti<span class="hlt">Al</span> was observed in only one of the four different stoichiometries studied, i.e., x = 1, as detected by XRD. Using this reaction, there is a constant amount of excess <span class="hlt">Al</span> and a variable excess of Ti. These stoichiometries produce composites with varying Ti-<span class="hlt">Al</span> ratios that allow the matrix composition of the composite to be varied along the concentration axis of the Ti-<span class="hlt">Al</span> phase diagram.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/scitech/biblio/21448880','SCIGOV-STC'); return false;" href="https://www.osti.gov/scitech/biblio/21448880"><span>{sup 60}Fe AND {sup 26}<span class="hlt">Al</span> IN CHONDRULES FROM UNEQUILIBRATED CHONDRITES: IMPLICATIONS FOR EARLY SOLAR <span class="hlt">SYSTEM</span> PROCESSES</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Mishra, R. K.; Goswami, J. N.; Rudraswami, N. G.; Tachibana, S.; Huss, G. R.</p> <p>2010-05-10</p> <p>The presence of about a dozen short-lived nuclides in the early solar <span class="hlt">system</span>, including {sup 60}Fe and {sup 26}<span class="hlt">Al</span>, has been established from isotopic studies of meteorite samples. An accurate estimation of solar <span class="hlt">system</span> initial abundance of {sup 60}Fe, a distinct product of stellar nucleosynthesis, is important to infer the stellar source of this nuclide. Previous studies in this regard suffered from the lack of exact knowledge of the time of formation of the analyzed meteorite samples. We present here results obtained from the first combined study of {sup 60}Fe and {sup 26}<span class="hlt">Al</span> records in early solar <span class="hlt">system</span> objects to remove this ambiguity. Chondrules from unequilibrated ordinary chondrites belonging to low petrologic grades were analyzed for their Fe-Ni and <span class="hlt">Al</span>-Mg isotope systematics. The <span class="hlt">Al</span>-Mg isotope data provide the time of formation of the analyzed chondrules relative to the first solar <span class="hlt">system</span> solids, the Ca-<span class="hlt">Al</span>-rich inclusions. The inferred initial {sup 60}Fe/{sup 56}Fe values of four chondrules, combined with their time of formation based on <span class="hlt">Al</span>-Mg isotope data, yielded a weighted mean value of (6.3 {+-} 2) x 10{sup -7} for solar <span class="hlt">system</span> initial {sup 60}Fe/{sup 56}Fe. This argues for a high-mass supernova as the source of {sup 60}Fe along with {sup 26}<span class="hlt">Al</span> and several other short-lived nuclides present in the early solar <span class="hlt">system</span>.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.osti.gov/scitech/servlets/purl/926171','SCIGOV-STC'); return false;" href="http://www.osti.gov/scitech/servlets/purl/926171"><span>Cooperative Research and Development of <span class="hlt">Primary</span> Surface Recuperator for Advanced Microturbine <span class="hlt">Systems</span></span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Escola, George</p> <p>2007-01-17</p> <p>Recuperators have been identified as key components of advanced gas turbines <span class="hlt">systems</span> that achieve a measure of improvement in operating efficiency and lead the field in achieving very low emissions. Every gas turbine manufacturer that is studying, developing, or commercializing advanced recuperated gas turbine cycles requests that recuperators operate at higher temperature without a reduction in design life and must cost less. The Solar Cooperative Research and Development of <span class="hlt">Primary</span> Surface Recuperator for Advanced Microturbine <span class="hlt">Systems</span> Program is directed towards meeting the future requirements of advanced gas turbine <span class="hlt">systems</span> by the following: (1) The development of advanced alloys that will allow recuperator inlet exhaust gas temperatures to increase without significant cost increase. (2) Further characterization of the creep and oxidation (dry and humid air) properties of nickel alloy foils (less than 0.13 mm thick) to allow the economical use of these materials. (3) Increasing the use of advanced robotic <span class="hlt">systems</span> and advanced in-process statistical measurement <span class="hlt">systems</span>.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/scitech/biblio/922165','SCIGOV-STC'); return false;" href="https://www.osti.gov/scitech/biblio/922165"><span>A Potentiometric, Spectrophotometric and Pitzer Ion-Interaction Study of Reaction Equilibria in the Aqueous H+-<span class="hlt">Al</span>3+, H+-Oxalate and H+-<span class="hlt">Al</span>3+-Oxalate <span class="hlt">Systems</span> up to 5 mol*dm-3 NaCl</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Boily, Jean F.; Qafoku, Odeta; Felmy, Andrew R.</p> <p>2007-12-01</p> <p>Aluminium-oxalate complexation was determined in acidic media of aqueous NaCl solutions ranging from 0.1-5.0 mol•dm-3. Complexation in the H+-<span class="hlt">Al</span>3+ and H+-Oxalate <span class="hlt">systems</span> was also studied to provide a set of internally consistent thermodynamic data. The ionic strength dependent formation constants describing the stabilities of the <span class="hlt">Al</span>3+, <span class="hlt">Al</span>OH2+, <span class="hlt">Al</span>3(OH)45+, <span class="hlt">Al</span>13O4(OH)247+, H2L, HL-, L2-, <span class="hlt">Al</span>L+, <span class="hlt">Al</span>L2- and <span class="hlt">Al</span>L33- species (where L is the oxalate ion) was also described using a Pitzer ion interaction model. The derived parameters can be used to predict chemical speciation in the H+-<span class="hlt">Al</span>3+-Oxalate <span class="hlt">system</span> in the 0.1-5.0 mol•dm-3 NaCl range.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/20146645','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/20146645"><span>Exceptional oral manifestations of amyloid light chain protein (<span class="hlt">AL</span>) <span class="hlt">systemic</span> amyloidosis.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Elad, Sharon; Czerninski, Rakefet; Fischman, Stuart; Keshet, Na'ama; Drucker, Scott; Davidovich, Tzipporah; Goldschmidt, Neta</p> <p>2010-03-01</p> <p>Oral amyloidosis is usually presented in the tongue and is often associated with multiple myeloma. We present three patients with unusual oral manifestations of <span class="hlt">primary</span> amyloidosis, which to the best of our knowledge have not been previously published. In two cases the oral manifestation was overt at the time of diagnosis and all cases ended in patient mortality. Since these oral manifestations can contribute to the diagnosis of <span class="hlt">systemic</span> amyloidosis, clinicians should be made aware of them. Future research should assess the significance of oral manifestation as a prognostic indicator.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/22426680','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/22426680"><span><span class="hlt">Primary</span> breast lymphoma sequentially relapsed in the peripheral and central nervous <span class="hlt">system</span>.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Tang, Tzung-Chih; Chang, Hung; Chuang, Wen-Yu</p> <p>2012-09-01</p> <p><span class="hlt">Primary</span> breast lymphoma (PBL) is an uncommon extranodal type of lymphoma, exhibiting more aggressive behavior and poorer prognosis. Patients with PBL have a higher incidence to relapse in central nervous <span class="hlt">system</span> (CNS), which is always leading to a dismal outcome even treating with high intensity chemotherapy plus radiotherapy. Lymphoma involving the peripheral nervous <span class="hlt">system</span> (PNS), either primarily or secondarily, is also rare. But no PBL with PNS relapse has been reported before. Herein, we reported a case of PBL who presented with subsequent relapse in two discrete sites of the PNS followed by the CNS.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://hdl.handle.net/2060/19850019660','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/19850019660"><span><span class="hlt">Primary</span> propulsion of electrothermal, ion and chemical <span class="hlt">systems</span> for space-based radar orbit transfer</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Wang, S. Y.; Staiger, P. J.</p> <p>1985-01-01</p> <p>An orbit transfer mission concept has been studied for a Space-Based Radar (SBR) where 40 kW required for radar operation is assumed available for orbit transfer propulsion. Arcjet, pulsed electrothermal (PET), ion, and storable chemical <span class="hlt">systems</span> are considered for the <span class="hlt">primary</span> propulsion. Transferring two SBR per shuttle flight to 1112 km/60 deg using electrical propulsion <span class="hlt">systems</span> offers an increased payload at the expense of increased trip time, up to 2000 kg each, which may be critical for survivability. Trade offs between payload mass, transfer time, launch site, inclination, and height of parking orbits are presented.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=19860029693&hterms=pets&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D70%26Ntt%3Dpets','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=19860029693&hterms=pets&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D70%26Ntt%3Dpets"><span><span class="hlt">Primary</span> propulsion of electrothermal, ion, and chemical <span class="hlt">systems</span> for space-based radar orbit transfer</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Wang, S.-Y.; Staiger, P. J.</p> <p>1985-01-01</p> <p>An orbit transfer mission concept has been studied for a Space-Based Radar (SBR) where 40 kW required for radar operation is assumed available for orbit transfer propulsion. Arcjet, pulsed electrothermal (PET), ion, and storable chemical <span class="hlt">systems</span> are considered for the <span class="hlt">primary</span> propulsion. Transferring two SBR per shuttle flight to 1112 km/60 deg using eiectrical propulsion <span class="hlt">systems</span> offers an increased payload at the expense of increased trip time, up to 2000 kg each, which may be critical for survivability. Trade offs between payload mass, transfer time, launch site, inclination, and height of parking orbits are presented.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26720646','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26720646"><span>Propagation Properties of the Precipitation Band in an <span class="hlt">Al</span>Cl₃/NaOH <span class="hlt">System</span>.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Ban, Takahiko; Nagatsu, Yuichiro; Tokuyama, Hideaki</p> <p>2016-01-19</p> <p>When inherently immobile solid particles collectively form precipitates in a reaction-diffusion <span class="hlt">system</span> involving a redissolution reaction, a propagation phenomenon may occur in which a dynamic pattern of precipitation bands forms. This propagating precipitation phenomenon has been studied by many researchers. However, two completely different processes-i.e., the reaction-diffusion of reactants and the crystal growth of products-progress simultaneously in the <span class="hlt">system</span>, thereby rendering the phenomenon complex. There are no well-established experimental laws for this propagating precipitation phenomenon, such as the spacing, time, and width laws associated with the well-known Liesegang phenomenon, which is static in the sense that precipitation bands form and remain at the same position. In fact, it has not been clarified which of the processes controls the propagation phenomenon. Accordingly, we have investigated the apparent diffusion coefficient associated with the dynamics of propagating precipitation band in an <span class="hlt">Al</span>Cl3/NaOH <span class="hlt">system</span> for the case in which a large excess of outer electrolytes (i.e., OH(-)) diffuses into gel in which inner electrolytes (i.e.,<span class="hlt">Al</span>(3+)) are homogeneously distributed. An isolated precipitation band of <span class="hlt">Al</span>(OH)3 was formed horizontally in a test tube and propagated vertically in proportion to the square root of time. In our experimental results, we found that the apparent diffusion coefficient, D(p), possesses an exponential dependence on the initial concentrations of the outer electrolyte, and the inner electrolyte; the measured relation was D(p) = D[<span class="hlt">Al</span>(3+)](-0.6)[OH(-)](0.6), where D = (0.63 ± 0.04) × 10(5) cm(2)/s. From our model equations based on the prenucleation theory, which take into account a redissolution reaction, we found that the dynamics of the reaction front of the outer and the inner electrolytes was an important factor in controlling the propagation of the precipitation band. In our simulation results, we obtained a similar</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/scitech/biblio/21300663','SCIGOV-STC'); return false;" href="https://www.osti.gov/scitech/biblio/21300663"><span>{sup 26}<span class="hlt">Al</span> AND THE FORMATION OF THE SOLAR <span class="hlt">SYSTEM</span> FROM A MOLECULAR CLOUD CONTAMINATED BY WOLF-RAYET WINDS</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Gaidos, Eric; Krot, Alexander N.; Williams, Jonathan P.; Raymond, Sean N. E-mail: sasha@higp.hawaii.edu E-mail: sean.raymond@colorado.edu</p> <p>2009-05-10</p> <p>In agreement with previous work, we show that the presence of the short-lived radionuclide (SLR) {sup 26}<span class="hlt">Al</span> in the early solar <span class="hlt">system</span> was unlikely (less than 2% a priori probability) to be the result of direct introduction of supernova (SN) ejecta into the gaseous disk during the Class II stage of protosolar evolution. We also show that Bondi-Hoyle accretion of any contaminated residual gas from the Sun's natal star cluster contributed negligible {sup 26}<span class="hlt">Al</span> to the primordial solar <span class="hlt">system</span>. Our calculations are consistent with the absence of the oxygen isotopic signature expected with any late introduction of SN ejecta into the protoplanetary disk. Instead, the presence of {sup 26}<span class="hlt">Al</span> in the oldest solar <span class="hlt">system</span> solids (calcium-aluminum-rich inclusions (CAIs)) and its apparent uniform distribution with the inferred canonical {sup 26}<span class="hlt">Al</span>/{sup 27}<span class="hlt">Al</span> ratio of (4.5-5) x 10{sup -5} support the inheritance of {sup 26}<span class="hlt">Al</span> from the Sun's parent giant molecular cloud. We propose that this radionuclide originated in a prior generation of massive stars that formed in the same molecular cloud and contaminated that cloud by Wolf-Rayet winds. We calculated the Galactic distribution of {sup 26}<span class="hlt">Al</span>/{sup 27}<span class="hlt">Al</span> ratios that arise from such contamination using the established embedded cluster mass and stellar initial mass functions, published nucleosynthetic yields from the winds of massive stars, and by assuming rapid and uniform mixing into the cloud. Although our model predicts that the majority of stellar <span class="hlt">systems</span> contain no {sup 26}<span class="hlt">Al</span> from massive stars, and that the a priori probability that the {sup 26}<span class="hlt">Al</span>/{sup 27}<span class="hlt">Al</span> ratio will reach or exceed the canonical solar <span class="hlt">system</span> value is only {approx}6%, the maximum in the distribution of nonzero values is close to the canonical {sup 26}<span class="hlt">Al</span>/{sup 27}<span class="hlt">Al</span> ratio. We find that the Sun most likely formed 4-5 million years (Myr) after the massive stars that were the source of {sup 26}<span class="hlt">Al</span>. Furthermore, our model can explain the initial solar <span class="hlt">system</span></p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/scitech/biblio/186789','SCIGOV-STC'); return false;" href="https://www.osti.gov/scitech/biblio/186789"><span>Combustion synthesis of metal-matrix composites. Part 3: The <span class="hlt">Al-TiC-Al</span>{sub 2}O{sub 3} <span class="hlt">system</span></span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Kunrath, A.O.; Strohaecker, T.R.; Moore, J.J.</p> <p>1996-01-15</p> <p>The principle of combustion synthesis to produce metal matrix composites has been outlined in earlier papers. Applying pressure either during or immediately after the reaction is completed is the most commonly used method to achieve high densification of the synthesized products. Some advanced ceramics (TiC and TiB{sub 2}) have been reported to achieve up to 95% of theoretical density using this technique. The current research is a continuation of the work on the TiC-<span class="hlt">Al</span>{sub 2}O{sub 3}-<span class="hlt">Al</span> <span class="hlt">system</span>, in which an excess amount of liquid aluminum is generated by the exothermic reaction and infiltrates the pores of the ceramic matrix improving the densification of the product. The current research is aimed at synthesizing high volume fractions, i.e., > 50%, metal matrix composites using the SHS reaction. The stability of this reaction is inversely proportional to the excess amount of the metal phase added to the reactants, i.e. x<span class="hlt">Al</span>. The excess <span class="hlt">Al</span> acts as a diluent, taking heat from the reaction front, and making it difficult to ignite and/or sustain the reaction in pellets with stoichiometries of high volume fractions of metal. For this reason, the simultaneous combustion (thermal explosion) mode was chosen to perform the synthesis reaction and in which the whole pellet is heated to the ignition temperature.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/scitech/biblio/1164045','SCIGOV-STC'); return false;" href="https://www.osti.gov/scitech/biblio/1164045"><span>Solution-based thermodynamic modeling of the Ni-<span class="hlt">Al</span>-Mo <span class="hlt">system</span> using first-principles calculations</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Zhou, S H; Wang, Y; Chen, L -Q; Liu, Z -K; Napolitano, R E</p> <p>2014-09-01</p> <p>A solution-based thermodynamic description of the ternary Ni–Al–Mo <span class="hlt">system</span> is developed here, incorporating first-principles calculations and reported modeling of the binary Ni–<span class="hlt">Al</span>, Ni–Mo and Al–Mo <span class="hlt">systems</span>. To search for the configurations with the lowest energies of the N phase, the Alloy Theoretic Automated Toolkit (ATAT) was employed and combined with VASP. The liquid, bcc and γ-fcc phases are modeled as random atomic solutions, and the γ'-Ni3<span class="hlt">Al</span> phase is modeled by describing the ordering within the fcc structure using two sublattices, summarized as (<span class="hlt">Al</span>,Mo,Ni)0.75(<span class="hlt">Al</span>,Mo,Ni)0.25. Thus, γ-fcc and γ'-Ni3<span class="hlt">Al</span> are modeled with a single Gibbs free energy function with appropriate treatment of the chemical ordering contribution. In addition, notable improvements are the following: first, the ternary effects of Mo and <span class="hlt">Al</span> in the B2-Ni<span class="hlt">Al</span> and D0a-Ni3Mo phases, respectively, are considered; second, the N-Ni<span class="hlt">Al</span>8Mo3 phase is described as a solid solution using a three-sublattice model; third, the X-Ni14<span class="hlt">Al</span>75Mo11 phase is treated as a stoichiometric compound. Model parameters are evaluated using first-principles calculations of zero-Kelvin formation enthalpies and reported experimental data. In comparison with the enthalpies of formation for the compounds ψ-<span class="hlt">Al</span>Mo, θ-<span class="hlt">Al</span>8Mo3 and B2-Ni<span class="hlt">Al</span>, the first-principles results indicate that the N-Ni<span class="hlt">Al</span>8Mo3 phase, which is stable at high temperatures, decomposes into other phases at low temperature. Resulting phase equilibria are summarized in the form of isothermal sections and liquidus projections. To clearly identify the relationship between the γ-fcc and γ'-Ni3<span class="hlt">Al</span> phases in the ternary Ni–Al–Mo <span class="hlt">system</span>, the specific γ-fcc and γ'-Ni3<span class="hlt">Al</span> phase fields are plotted in x(<span class="hlt">Al</span>)–x(Mo)–T space for a temperature range 1200–1800 K.</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_12");'>12</a></li> <li><a href="#" onclick='return showDiv("page_13");'>13</a></li> <li class="active"><span>14</span></li> <li><a href="#" onclick='return showDiv("page_15");'>15</a></li> <li><a href="#" onclick='return showDiv("page_16");'>16</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_14 --> <div id="page_15" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_13");'>13</a></li> <li><a href="#" onclick='return showDiv("page_14");'>14</a></li> <li class="active"><span>15</span></li> <li><a href="#" onclick='return showDiv("page_16");'>16</a></li> <li><a href="#" onclick='return showDiv("page_17");'>17</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="281"> <li> <p><a target="_blank" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=19920041145&hterms=ALS&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D10%26Ntt%3DALS','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=19920041145&hterms=ALS&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D10%26Ntt%3DALS"><span>Aerodynamics of the advanced launch <span class="hlt">system</span> (<span class="hlt">ALS</span>) propulsion and avionics (P/A) module</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Ferguson, Stan; Savage, Dick</p> <p>1992-01-01</p> <p>This paper discusses the design and testing of candidate Advanced Launch <span class="hlt">System</span> (<span class="hlt">ALS</span>) Propulsion and Avionics (P/A) Module configurations. The P/A Module is a key element of future launch <span class="hlt">systems</span> because it is essential to the recovery and reuse of high-value propulsion and avionics hardware. The <span class="hlt">ALS</span> approach involves landing of first stage (booster) and/or second stage (core) P/A modules near the launch site to minimize logistics and refurbishment cost. The key issue addressed herein is the aerodynamic design of the P/A module, including the stability characteristics and the lift-to-drag (L/D) performance required to achieve the necessary landing guidance accuracy. The reference P/A module configuration was found to be statically stable for the desired flight regime, to provide adequate L/D for targeting, and to have effective modulation of the L/D performance using a body flap. The hypersonic aerodynamic trends for nose corner radius, boattail angle and body flap deflections were consistent with pretest predictions. However, the levels for the L/D and axial force for hypersonic Mach numbers were overpredicted by impact theories.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016ISPAnIII3..233W','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016ISPAnIII3..233W"><span>Uls LiDAR Supported Analyses of Laser Beam Penetration from Different <span class="hlt">ALS</span> <span class="hlt">Systems</span> Into Vegetation</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Wieser, M.; Hollaus, M.; Mandlburger, G.; Glira, P.; Pfeifer, N.</p> <p>2016-06-01</p> <p>This study analyses the underestimation of tree and shrub heights for different airborne laser scanner <span class="hlt">systems</span> and point cloud distribution within the vegetation column. Reference data was produced by a novel UAV-borne laser scanning (ULS) with a high point density in the complete vegetation column. With its physical parameters (e.g. footprint) and its relative accuracy within the block as stated in Section 2.2 the reference data is supposed to be highly suitable to detect the highest point of the vegetation. An airborne topographic (<span class="hlt">ALS</span>) and topo-bathymetric (ALB) <span class="hlt">system</span> were investigated. All data was collected in a period of one month in leaf-off condition, while the dominant tree species in the study area are deciduous trees. By robustly estimating the highest 3d vegetation point of each laser <span class="hlt">system</span> the underestimation of the vegetation height was examined in respect to the ULS reference data. This resulted in a higher under-estimation of the airborne topographic <span class="hlt">system</span> with 0.60 m (trees) and 0.55 m (shrubs) than for the topo-bathymetric <span class="hlt">system</span> 0.30 m (trees) and 0.40 m (shrubs). The degree of the underestimation depends on structural characteristics of the vegetation itself and physical specification of the laser <span class="hlt">system</span>.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015ApSS..355..930S','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015ApSS..355..930S"><span>Influence of SiC surface polarity on the wettability and reactivity in an <span class="hlt">Al</span>/SiC <span class="hlt">system</span></span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Shen, Ping; Wang, Yi; Ren, Lihua; Li, Shixin; Liu, Yuhua; Jiang, Qichuan</p> <p>2015-11-01</p> <p>The wetting of (0 0 0 1) 6H-SiC single crystals by molten <span class="hlt">Al</span> was investigated using a dispensed sessile drop method in a high vacuum at 973-1173 K. The wettability and reactivity in this <span class="hlt">system</span> are sensitive to the surface polarity of SiC. The interfacial reaction on the Si-terminated surface is rapid. The formation of a continuous <span class="hlt">Al</span>4C3 product layer at the interface leads to an equilibrium contact angle of 56 ± 1° at 1173 K. In comparison, the interfacial reaction on the C-terminated surface is sluggish. The interface is only partially covered by discrete <span class="hlt">Al</span>4C3 platelets even after dwelling at 1173 K for 2 h. The final wettability, however, is much better (θF = 41 ± 1°) than that of the Si-terminated surface which was covered by a dense <span class="hlt">Al</span>4C3 layer, suggesting that the formation of <span class="hlt">Al</span>4C3 should not always contribute to the wetting in the <span class="hlt">Al</span>/SiC <span class="hlt">system</span>. A plausible explanation is that the clean (i.e., deoxidized) C-terminated surface should be well wetted by molten <span class="hlt">Al</span> in nature, owing to the strong chemical interactions between liquid <span class="hlt">Al</span> and the surface atoms of the C-terminated SiC. It is likely that the presence of the oxide film at the surface of the molten <span class="hlt">Al</span> drop or the SiC substrate and the rapid formation of <span class="hlt">Al</span>4C3, which prevent the establishment of a real <span class="hlt">Al</span>/SiC interface, conceal the intrinsic wettability of this <span class="hlt">system</span>.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.osti.gov/scitech/servlets/purl/431177','SCIGOV-STC'); return false;" href="http://www.osti.gov/scitech/servlets/purl/431177"><span>Environmental standards for <span class="hlt">primary</span> and secondary containment <span class="hlt">systems</span> and transfer stations</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Maguire, D.M.</p> <p>1995-04-01</p> <p>Environmental Standards for <span class="hlt">Primary</span> and Secondary Containment <span class="hlt">Systems</span> and Transfer Stations will supersede all previous requirements for design of dikes, storage tanks, and transfer stations in order to maintain consistency throughout the Y-12 Plant. This document is organized into six distinct sections, each with a specific purpose. Section I outlines the objectives of the document along with its applications and limitations; this section should be of interest to all readers for essential background information. Section II lists all definitions and is consistent with definitions outlined by environmental regulations. Section III discusses <span class="hlt">primary</span> containment standards. Section IV outlines secondary containment standards; this section contains the actual standards for the diking of storage tanks and storage containers. Section V discusses transfer station standards. Section VI of this document outlines how exemptions may be granted for specific cases.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1378148','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1378148"><span>Gut mucosal nutritional support--enteral nutrition as <span class="hlt">primary</span> therapy after multiple <span class="hlt">system</span> trauma.</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Kudsk, K A</p> <p>1994-01-01</p> <p>Over the past 10 years, several clinical and experimental studies report the potential benefit of enteral nutrition as <span class="hlt">primary</span> therapy after multiple <span class="hlt">system</span> trauma. In this study, 98 patients sustaining blunt and penetrating trauma were randomised to receive either enteral or parenteral feeding for 15 days. There were significantly fewer infectious complications in patients randomised to receive enteral feeding with particular benefit shown in the most severely injured patients. Serum protein concentrations correlated with the clinical outcome with an increase in constitutive protein and decrease in acute phase protein concentrations occurring in the enteral group through a decrease in septic complications and possible direct hepatic 'reprioritisation'. Enteral feeding serves as a <span class="hlt">primary</span> therapy affecting the outcome of critically ill patients. PMID:8125392</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3215502','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3215502"><span>Colon Targeted Drug Delivery <span class="hlt">Systems</span>: A Review on <span class="hlt">Primary</span> and Novel Approaches</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Philip, Anil K.; Philip, Betty</p> <p>2010-01-01</p> <p>The colon is a site where both local and <span class="hlt">systemic</span> delivery of drugs can take place. Local delivery allows topical treatment of inflammatory bowel disease. However, treatment can be made effective if the drugs can be targeted directly into the colon, thereby reducing the <span class="hlt">systemic</span> side effects. This review, mainly compares the <span class="hlt">primary</span> approaches for CDDS (Colon Specific Drug Delivery) namely prodrugs, pH and time dependent <span class="hlt">systems</span>, and microbially triggered <span class="hlt">systems</span>, which achieved limited success and had limitations as compared with newer CDDS namely pressure controlled colonic delivery capsules, CODESTM, and osmotic controlled drug delivery which are unique in terms of achieving in vivo site specificity, and feasibility of manufacturing process. PMID:22125706</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=19920071474&hterms=PPS&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D50%26Ntt%3DPPS','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=19920071474&hterms=PPS&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D50%26Ntt%3DPPS"><span>Design and testing of the U.S. Space Station Freedom <span class="hlt">primary</span> propulsion <span class="hlt">system</span></span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Morano, Joseph S.; Delventhal, Rex A.; Chilcot, Kimberly J.</p> <p>1992-01-01</p> <p>The <span class="hlt">primary</span> propulsion <span class="hlt">system</span> (PPS) for the Space Station Freedom is discussed in terms of salient design characteristics and key testing procedures. The rocket engine modules contain reboost and attitude control thrusters, and their designs are illustrated showing the mounting structures, thruster solenoid valves, and thrust chambers. The propellant tank assembly for storing gaseous N pressurant and hydrazine propellant is described as are the <span class="hlt">system</span> avionics, thruster solenoid valves, and latching isolation valves. PPS testing conducted on the development <span class="hlt">systems</span> includes the use of a propulsion-module development unit, a development test article, and <span class="hlt">system</span> qualification testing. Specific test articles include functional heaters, mass/thermal simulated components, flight-quality structures, and software control operations.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/1992jpnt.confTW...M','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/1992jpnt.confTW...M"><span>Design and testing of the U.S. Space Station Freedom <span class="hlt">primary</span> propulsion <span class="hlt">system</span></span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Morano, Joseph S.; Delventhal, Rex A.; Chilcot, Kimberly J.</p> <p>1992-07-01</p> <p>The <span class="hlt">primary</span> propulsion <span class="hlt">system</span> (PPS) for the Space Station Freedom is discussed in terms of salient design characteristics and key testing procedures. The rocket engine modules contain reboost and attitude control thrusters, and their designs are illustrated showing the mounting structures, thruster solenoid valves, and thrust chambers. The propellant tank assembly for storing gaseous N pressurant and hydrazine propellant is described as are the <span class="hlt">system</span> avionics, thruster solenoid valves, and latching isolation valves. PPS testing conducted on the development <span class="hlt">systems</span> includes the use of a propulsion-module development unit, a development test article, and <span class="hlt">system</span> qualification testing. Specific test articles include functional heaters, mass/thermal simulated components, flight-quality structures, and software control operations.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2010SPIE.7622E..2AG','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2010SPIE.7622E..2AG"><span>Optimization of <span class="hlt">system</span> parameters for modulator design in x-ray scatter correction using <span class="hlt">primary</span> modulation</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Gao, Hewei; Zhu, Lei; Fahrig, Rebecca</p> <p>2010-04-01</p> <p>The impact of the <span class="hlt">system</span> parameters of the modulator on X-ray scatter correction using <span class="hlt">primary</span> modulation is studied and an optimization of the modulator design is presented. Recently, a promising scatter correction method for X-ray computed tomography (CT) that uses a checkerboard pattern of attenuating blockers (<span class="hlt">primary</span> modulator) placed between the X-ray source and the object has been developed and experimentally verified. The blocker size, d, and the blocker transmission factor, α, are critical to the performance of the <span class="hlt">primary</span> modulation method. In this work, an error caused by aliasing of <span class="hlt">primary</span> whose magnitude depends on the choices of d and α, and the scanned object, is set as the object function to be minimized, with constraints including the X-ray focal spot, the physical size of the detector element, and the noise level. The optimization is carried out in two steps. In the first step, d is chosen as small as possible but should meet a lower-bound condition. In the second step, α should be selected to balance the error level in the scatter estimation and the noise level in the reconstructed image. The lower bound of d on our tabletop CT <span class="hlt">system</span> is 0.83 mm. Numerical simulations suggest 0.6 < α < 0.8 is appropriate. Using a Catphan 600 phantom, a copper modulator (d = 0.89 mm, α = 0.70) expectedly outperforms an aluminum modulator (d = 2.83 mm, α = 0.90). With the aluminum modulator, our method reduces the average error of CT number in selected contrast rods from 371.4 to 25.4 Hounsfield units (HU) and enhances the contrast to noise ratio (CNR) from 10.9 to 17.2; when the copper modulator is used, the error is further reduced to 21.9 HU and the CNR is further increased to 19.2.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/scitech/biblio/21370547','SCIGOV-STC'); return false;" href="https://www.osti.gov/scitech/biblio/21370547"><span>Thermal transformation of quaternary compounds in NaF-CaF{sub 2}-<span class="hlt">Al</span>F{sub 3} <span class="hlt">system</span></span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Zaitseva, Julia N.; Yakimov, Igor S.; Kirik, Sergei D.</p> <p>2009-08-15</p> <p>Details of quaternary compounds formation in the <span class="hlt">system</span> NaF-CaF{sub 2}-<span class="hlt">Al</span>F{sub 3} are specified. To achieve this aim, the samples of phases NaCa<span class="hlt">Al</span>F{sub 6} and Na{sub 2}Ca{sub 3}<span class="hlt">Al</span>{sub 2}F{sub 14} have been obtained by high-temperature solid-phase synthesis. Their thermal behavior when heated up to 800 deg. C has been studied using the methods of high-temperature X-ray diffraction (XRD) and thermal analysis (TA). The <span class="hlt">system</span> under consideration can be regarded as a quasibinary section CaF{sub 2}-Na<span class="hlt">Al</span>F{sub 4}, where at T=745-750 deg. C invariant equilibrium is implemented with the phases CaF{sub 2}-NaCa<span class="hlt">Al</span>F{sub 6}-Na{sub 2}Ca{sub 3}<span class="hlt">Al</span>{sub 2}F{sub 14}-(liquid melt)-(Na<span class="hlt">Al</span>F{sub 4}). The peculiarity of the equilibrium is Na<span class="hlt">Al</span>F{sub 4} metastability at normal pressure. Below the equilibrium temperature the quaternary phase Na{sub 2}Ca{sub 3}<span class="hlt">Al</span>{sub 2}F{sub 14} is stable and NaCa<span class="hlt">Al</span>F{sub 6} above this temperature. The phase NaCa<span class="hlt">Al</span>F{sub 6} fixed by rapid quenching from high temperatures and when heated up to 640 deg. C decomposes, yielding Na{sub 2}Ca{sub 3}<span class="hlt">Al</span>{sub 2}F{sub 14}. Further heating in vacuum at temperature up to 740 deg. C results in decomposition of Na{sub 2}Ca{sub 3}<span class="hlt">Al</span>{sub 2}F{sub 14} into CaF{sub 2} and Na{sub 3}<span class="hlt">Al</span>F{sub 6}. The expected reverse transformation of Na{sub 2}Ca{sub 3}<span class="hlt">Al</span>{sub 2}F{sub 14} into NaCa<span class="hlt">Al</span>F{sub 6} has not been observed under experimental conditions. Transformations in bulk samples reveal direct and reverse transformation of quaternary phases. Synopsis: Thermal transformation of the quaternary compounds in <span class="hlt">system</span> (NaF-CaF{sub 2}-<span class="hlt">Al</span>F{sub 3}) was investigated using high-temperature X-ray diffraction (XRD) and thermal analysis (TA). In the <span class="hlt">system</span> the invariant equilibrium is implemented with the phases CaF{sub 2}-NaCa<span class="hlt">Al</span>F{sub 6}-Na{sub 2}Ca{sub 3}<span class="hlt">Al</span>{sub 2}F{sub 14}-(liquid melt)-(Na<span class="hlt">Al</span>F{sub 4}) at T=745-750 deg. C. - Graphical Abstract: The paper concerns of a small piece of the ternary <span class="hlt">system</span> (NaF-CaF{sub 2}-<span class="hlt">Al</span>F{sub 3}) which is very important for</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.osti.gov/scitech/servlets/purl/991923','SCIGOV-STC'); return false;" href="http://www.osti.gov/scitech/servlets/purl/991923"><span>EVALUATION OF BEST AVAILABLE CONTROL TECHNOLOGY FOR TOXICS (TBACT) DOUBLE SHELL TANK FARMS <span class="hlt">PRIMARY</span> VENTILATION <span class="hlt">SYSTEM</span> SUPPORTING WASTE TRANSFER OPERATIONS</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>KELLY SE; HAASS CC; KOVACH JL; TURNER DA</p> <p>2010-06-03</p> <p>This report is an evaluation of Best Available Control Technology for Toxics (tBACT) for installation and operation of the Hanford double shell (DST) tank <span class="hlt">primary</span> ventilation <span class="hlt">systems</span>. The DST <span class="hlt">primary</span> ventilation <span class="hlt">systems</span> are being modified to support Hanford's waste retrieval, mixing, and delivery of single shell tank (SST) and DST waste throught the DST storage <span class="hlt">system</span> to the Waste Treatment and Immobilization Plant (WTP).</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.osti.gov/scitech/servlets/purl/991873','SCIGOV-STC'); return false;" href="http://www.osti.gov/scitech/servlets/purl/991873"><span>EVALUATION OF BEST AVAILABLE CONTROL TECHNOLOGY FOR TOXICS -TBACT- DOUBLE SHELL TANK FARMS <span class="hlt">PRIMARY</span> VENTILATION <span class="hlt">SYSTEMS</span> SUPPORTING WASTE TRANSFER OPERATIONS</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>HAAS CC; KOVACH JL; KELLY SE; TURNER DA</p> <p>2010-06-24</p> <p>This report is an evaluation of Best Available Control Technology for Toxics (tBACT) for installation and operation of the Hanford double shell (DST) tank <span class="hlt">primary</span> ventilation <span class="hlt">systems</span>. The DST <span class="hlt">primary</span> ventilation <span class="hlt">systems</span> are being modified to support Hanford's waste retrieval, mixing, and delivery of single shell tank (SST) and DST waste through the DST storage <span class="hlt">system</span> to the Waste Treatment and Immobilizaiton Plant (WTP).</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.gpo.gov/fdsys/pkg/FR-2010-03-15/pdf/2010-5519.pdf','FEDREG'); return false;" href="https://www.gpo.gov/fdsys/pkg/FR-2010-03-15/pdf/2010-5519.pdf"><span>75 FR 12256 - United States, et <span class="hlt">al</span>. v. Election <span class="hlt">Systems</span> and Software, Inc.; Proposed Final Judgment and...</span></a></p> <p><a target="_blank" href="http://www.gpo.gov/fdsys/browse/collection.action?collectionCode=FR">Federal Register 2010, 2011, 2012, 2013, 2014</a></p> <p></p> <p>2010-03-15</p> <p>... Antitrust Division United States, et <span class="hlt">al</span>. v. Election <span class="hlt">Systems</span> and Software, Inc.; Proposed Final Judgment and.... v. Election <span class="hlt">Systems</span> and Software Inc., Civil Action No. 10-00380. On March 8, 2010, the United States filed a Complaint alleging that the proposed acquisition by Election <span class="hlt">Systems</span> and Software,...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.gpo.gov/fdsys/pkg/FR-2011-06-15/pdf/2011-14628.pdf','FEDREG'); return false;" href="https://www.gpo.gov/fdsys/pkg/FR-2011-06-15/pdf/2011-14628.pdf"><span>76 FR 35017 - United States et <span class="hlt">al</span>. v. United Regional Health Care <span class="hlt">System</span>; Public Comments and Response on...</span></a></p> <p><a target="_blank" href="http://www.gpo.gov/fdsys/browse/collection.action?collectionCode=FR">Federal Register 2010, 2011, 2012, 2013, 2014</a></p> <p></p> <p>2011-06-15</p> <p>... Antitrust Division United States et <span class="hlt">al</span>. v. United Regional Health Care <span class="hlt">System</span>; Public Comments and Response... States and State of Texas v. United Regional Health Care <span class="hlt">System</span>, Civil Action No. 7:11-cv- 00030-0, which.... United Regional Health Care <span class="hlt">System</span>, Defendant. Case No.: 7:11-cv-00030 Response Of Plaintiff...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/scitech/biblio/1347806','SCIGOV-STC'); return false;" href="https://www.osti.gov/scitech/biblio/1347806"><span>An Icosahedral Quasicrystal and Its 1/0 Crystalline Approximant in the Ca–Au–<span class="hlt">Al</span> <span class="hlt">System</span></span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Pham, Joyce; Kreyssig, Andreas; Goldman, Alan I.; Miller, Gordon J.</p> <p>2016-10-17</p> <p>A new icosahedral quasicrystalline phase, CaAu4.5–x<span class="hlt">Al</span>1.5+x [0.11 ≤ x ≤ 0.40(6); CaAu4.4<span class="hlt">Al</span>1.6, aQC = 5.383(4) Å, and Pm35], and its lowest-order 1/0 cubic crystalline approximant phase, CaAu3+x<span class="hlt">Al</span>1–x [0 ≤ x ≤ 0.31(1); a = 9.0766(5)–9.1261(8) Å, Pa3(No. 205), and Pearson symbol cP40], have been discovered in the Ca-poor region of the Ca–Au–<span class="hlt">Al</span> <span class="hlt">system</span>. In the crystalline approximant, eight [Au3–x<span class="hlt">Al</span>1+x] tetrahedra fill the unit cell, and each tetrahedron is surrounded by four Ca atoms, thus forming a three-dimensional network of {Ca4/4[Au3–x<span class="hlt">Al</span>1+x]} tetrahedral stars. A computational study of Au and <span class="hlt">Al</span> site preferences concurs with the experimental results, which indicate a preference for near-neighbor Au–<span class="hlt">Al</span> interactions over Au–Au and Al–<span class="hlt">Al</span> interactions. Analysis of the electronic density of states and the associated crystal orbital Hamilton population curves was used to rationalize the descriptions of CaAu4.5–x<span class="hlt">Al</span>1.5+x [0.11 ≤ x ≤ 0.46(6)] and CaAu3+x<span class="hlt">Al</span>1–x [0 ≤ x ≤ 0.31(1)] as polar intermetallic species, whereby Ca atoms engage in polar covalent bonding with the electronegative, electron-deficient [Au3–x<span class="hlt">Al</span>1+x] tetrahedral clusters and the observed phase width of the crystalline approximant.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/23321962','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/23321962"><span>EHR <span class="hlt">systems</span> in the Spanish Public Health National <span class="hlt">System</span>: the lack of interoperability between <span class="hlt">primary</span> and specialty care.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>de la Torre-Díez, Isabel; González, Sandra; López-Coronado, Miguel</p> <p>2013-02-01</p> <p>One of the problems of the Spanish Public Health National <span class="hlt">System</span> is the lack of interoperability in the implemented Electronic Health Records (EHRs) <span class="hlt">systems</span> in <span class="hlt">primary</span> and specialty care. There is a deficiency in the electronic health <span class="hlt">systems</span> that store the data of <span class="hlt">primary</span> care patients, so one of the basic problems that prevent that every hospital and health center working on the same method is that deficiency. In this paper we research on this problem and to give expression to a series of solutions to it. Bibliographic material in this work has been obtained mainly from MEDLINE source. Additionally, due to the lack of information and privacy about the different EHRs <span class="hlt">systems</span>, we have resorted to making direct contact with the organizations that have implemented those <span class="hlt">systems</span> and technological providers. Two solutions have been propounded given several aspects for a feasibility study. The first solution is based upon in the execution of backups in different EHRs databases, which implies a huge economical and infrastructure development. The second of these solutions so that due to the creation of protocols by means of Cloud Computing Technologies. It is crucial the need to reach a homogeneity concerning to the storage of patients clinical data. On the results achieved we can emphasize that maybe the main problems are not the economical handicaps or the large technological development needed, but, as for Health each Region manages its own competences, each one governs with independent policies and decisions.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017MMTB..tmp...60J','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017MMTB..tmp...60J"><span>Phase Equilibria in the <span class="hlt">System</span> "FeO"-CaO-SiO2-<span class="hlt">Al</span>2O3-MgO at Different CaO/SiO2 Ratios</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Jang, Kyoung-oh; Ma, Xiaodong; Zhu, Jinming; Xu, Haifa; Wang, Geoff; Zhao, Baojun</p> <p>2017-03-01</p> <p>The "FeO"-containing slags play an important role in the operation of an ironmaking blast furnace (BF), in particular the <span class="hlt">primary</span> slags such as the <span class="hlt">system</span> "FeO"-CaO-SiO2-<span class="hlt">Al</span>2O3-2 mass pct MgO with CaO/SiO2 weight ratios of 1.3, 1.5, and 1.8 saturated with metallic iron. To investigate the characteristics of such a slag <span class="hlt">system</span> and its behavior in BF, the phase equilibria and liquidus temperatures in the slag <span class="hlt">system</span> have been experimentally determined using the high-temperature equilibration and quenching technique followed by an electron probe X-ray microanalysis (EPMA). Isotherms between 1553 K and 1603 K (1280 °C and 1330 °C) were determined in the <span class="hlt">primary</span> phase fields of dicalcium silicate, melilite, spinel, and monoxide [(Mg,Fe2+)O]. Pseudo-ternary phase diagrams of (CaO + SiO2)-<span class="hlt">Al</span>2O3-"FeO" with a fixed MgO concentration at 2 mass pct and at CaO/SiO2 ratios of 1.3, 1.5, and 1.8 have been discussed, respectively, simplifying the complexity of the slag <span class="hlt">system</span> for easy understanding and applying in BF operation. It was found that the liquidus temperatures increase in melilite and spinel <span class="hlt">primary</span> phase fields, but decrease in dicalcium silicate and monoxide <span class="hlt">primary</span> phase fields with increasing <span class="hlt">Al</span>2O3/(CaO + SiO2) ratio. In addition, the liquidus temperatures decrease with increasing "FeO" concentration in dicalcium silicate and melilite <span class="hlt">primary</span> phase fields, while showing an increasing trend in the spinel and monoxide <span class="hlt">primary</span> phase fields. The data resulted from this study can be used to improve and optimize currently available database of thermodynamic models used in FactSage.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/12038521','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/12038521"><span><span class="hlt">Primary</span> lymphoma of the central nervous <span class="hlt">system</span> and HTLV-I infection.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Calderón, Enrique J; Japón, Miguel A; Chinchón, Isidoro; Soriano, Vicente; Capote, Francisco J</p> <p>2002-01-01</p> <p>Only a few cases of AIDS-related <span class="hlt">primary</span> lymphomas of the central nervous <span class="hlt">system</span> (CNS) show a T-cell phenotype. We have recently studied two intravenous drug users with HIV infection who had <span class="hlt">primary</span> CNS T-cell lymphomas. In both cases, the enzyme immunoassay (EIA) for HTLV gave a positive result. In the first case, study by western-blot (WB) and specific PCR confirmed the human T-cell lymphotropic virus type I (HTLV-I) infection and serological study by EIA for HTLV of his mother was negative. In the second case, analysis of ante-mortem serum samples by two different WBs showed an indeterminate pattern suggestive of HTLV-I infection, but adequate samples for PCR were not available. We speculate about the possibility that the horizontal transmission of HTLV-I infection could have facilitated the devepolment of a <span class="hlt">primary</span> CNS T-cell lymphoma in these HIV patients, although they cannot be strictly considered as ATLL cases.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/22893524','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/22893524"><span>Heat transfer characteristics of current <span class="hlt">primary</span> packaging <span class="hlt">systems</span> for pharmaceutical freeze-drying.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Hibler, Susanne; Gieseler, Henning</p> <p>2012-11-01</p> <p>In the field of freeze-drying, the <span class="hlt">primary</span> packaging material plays an essential role. Here, the packaging <span class="hlt">system</span> not only contains and protects the drug product during storage and shipping, but it is also directly involved in the freeze-drying process itself. The heat transfer characteristics of the actual container <span class="hlt">system</span> influence product temperature and therefore product homogeneity and quality as well as process performance. Consequently, knowledge of the container heat transfer characteristics is of vital importance for process optimization. It is the objective of this review article to provide a summary of research focused on heat transfer characteristics of different container <span class="hlt">systems</span> for pharmaceutical freeze-drying. Besides the common tubing and molded glass vials and metal trays, more recent packaging solutions like polymer vials, LYOGUARD® trays, syringes, and blister packs are discussed. Recent developments in vial manufacturing are also taken into account.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27555368','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27555368"><span>The Simplest Chronoscope V: A Theory of Dual <span class="hlt">Primary</span> and Secondary Reaction Time <span class="hlt">Systems</span>.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Montare, Alberto</p> <p>2016-12-01</p> <p>Extending work by Montare, visual simple reaction time, choice reaction time, discriminative reaction time, and overall reaction time scores obtained from college students by the simplest chronoscope (a falling meterstick) method were significantly faster as well as significantly less variable than scores of the same individuals from electromechanical reaction timers (machine method). Results supported the existence of dual reaction time <span class="hlt">systems</span>: an ancient <span class="hlt">primary</span> reaction time <span class="hlt">system</span> theoretically activating the V5 parietal area of the dorsal visual stream that evolved to process significantly faster sensory-motor reactions to sudden stimulations arising from environmental objects in motion, and a secondary reaction time <span class="hlt">system</span> theoretically activating the V4 temporal area of the ventral visual stream that subsequently evolved to process significantly slower sensory-perceptual-motor reactions to sudden stimulations arising from motionless colored objects.</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_13");'>13</a></li> <li><a href="#" onclick='return showDiv("page_14");'>14</a></li> <li class="active"><span>15</span></li> <li><a href="#" onclick='return showDiv("page_16");'>16</a></li> <li><a href="#" onclick='return showDiv("page_17");'>17</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_15 --> <div id="page_16" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_14");'>14</a></li> <li><a href="#" onclick='return showDiv("page_15");'>15</a></li> <li class="active"><span>16</span></li> <li><a href="#" onclick='return showDiv("page_17");'>17</a></li> <li><a href="#" onclick='return showDiv("page_18");'>18</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="301"> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4512937','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4512937"><span><span class="hlt">System</span> facilitators and barriers to discussing older driver safety in <span class="hlt">primary</span> care settings</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Betz, Marian E.; Jones, Jacqueline; Carr, David B.</p> <p>2015-01-01</p> <p>Background <span class="hlt">Primary</span> care physicians play a leading role in counseling older drivers, but discussions often do not occur until safety concerns arise. Prior work suggests that routine questioning about driving might facilitate these difficult conversations. Objective To explore <span class="hlt">system</span>-level factors affecting driving discussions in <span class="hlt">primary</span> care settings, in order to inform the design and implementation of a program supporting routine conversations. Methods This qualitative descriptive study used iterative interviews with providers (physicians, nurses, medical assistants, social workers, and administrative staff) working at two clinics (one geriatric, one general internal medicine) at a tertiary-care teaching hospital. General inductive techniques in transcript analysis were used to identify stakeholder-perceived <span class="hlt">system</span>-level barriers and facilitators to routine conversations with older drivers. Results From fifteen interviews, four themes emerged: (1) complexity of defined provider roles within <span class="hlt">primary</span> care setting (which can both support team work and hamper efficiency); (2) inadequate resources to support providers (including clinical prompts, local guides, and access to social workers and driving specialists); (3) gaps in education of providers and patients about discussing driving; and (4) suggested models to enhance provider conversations with older drivers (including following successful examples and using defined pathways integrated into the electronic medical record). A fifth theme was that participants characterized their experiences in terms of current and ideal states. Conclusions Physicians have been tasked with assessing older driver safety and guiding older patients through the process of “driving retirement.” Attention to <span class="hlt">system</span>-level factors such as provider roles, resources, and training can support them in this process. PMID:25617342</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/24047379','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/24047379"><span>Not lost in translation: generalization of the <span class="hlt">primary</span> <span class="hlt">systems</span> hypothesis to Japanese-specific language processes.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Ueno, Taiji; Saito, Satoru; Saito, Akie; Tanida, Yuki; Patterson, Karalyn; Lambon Ralph, Matthew A</p> <p>2014-02-01</p> <p>The emergentist-connectionist approach assumes that language processing reflects interaction between <span class="hlt">primary</span> neural <span class="hlt">systems</span> (<span class="hlt">Primary</span> <span class="hlt">Systems</span> Hypothesis). This idea offers an overarching framework that generalizes to various kinds of (English) language and nonverbal cognitive activities. The current study advances this approach with respect to language in two new and important ways. The first is the provision of a neuroanatomically constrained implementation of the theory. The second is a test of its ability to generalize to a language other than English (in this case Japanese) and, in particular, to a feature of that language (pitch accent) for which there is no English equivalent. A corpus analysis revealed the presence and distribution of typical and atypical accent forms in Japanese vocabulary, forming a quasiregular domain. Consequently, according to the <span class="hlt">Primary</span> <span class="hlt">Systems</span> Hypothesis, there should be a greater semantic impact on the processing of words with an atypical pitch accent. In turn, when word meaning is intrinsically less rich (e.g., abstract words), speakers should be prone to regularization errors of pitch accent. We explored these semantic-phonological interactions, first, in a neuroanatomically constrained, parallel-distributed processing model of spoken language processing. This model captured the accent typicality effect observed in nonword repetition in Japanese adults and children and exhibited the predicted semantic impact on repetition of words with atypical accent patterns. Second, also as predicted, in word repetition and immediate serial recall of spoken words, human participants exhibited reduced pitch-accent accuracy and/or slower RT for low imageability words with atypical accent patterns, and they generated accent errors reflecting the more typical accent patterns found in Japanese.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/20494505','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/20494505"><span>Work stress of <span class="hlt">primary</span> care physicians in the US, UK and German health care <span class="hlt">systems</span>.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Siegrist, Johannes; Shackelton, Rebecca; Link, Carol; Marceau, Lisa; von dem Knesebeck, Olaf; McKinlay, John</p> <p>2010-07-01</p> <p>Work-related stress among physicians has been an issue of growing concern in recent years. How and why this may vary between different health care <span class="hlt">systems</span> remains poorly understood. Using an established theoretical model (effort-reward imbalance), this study analyses levels of work stress among <span class="hlt">primary</span> care physicians (PCPs) in three different health care <span class="hlt">systems</span>, the United States, the United Kingdom and Germany. Whether professional autonomy and specific features of the work environment are associated with work stress and account for possible country differences are examined. Data are derived from self-administered questionnaires obtained from 640 randomly sampled physicians recruited for an international comparative study of medical decision making conducted from 2005 to 2007. Results demonstrate country-specific differences in work stress with the highest level in Germany, intermediate level in the US and lowest level among UK physicians. A negative correlation between professional autonomy and work stress is observed in all three countries, but neither this association nor features of the work environment account for the observed country differences. Whether there will be adequate numbers of PCPs, or even a field of <span class="hlt">primary</span> care in the future, is of increasing concern in several countries. To the extent that work-related stress contributes to this, identification of its organizational correlates in different health care <span class="hlt">systems</span> may offer opportunities for remedial interventions.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5114190','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5114190"><span>A Case of <span class="hlt">Primary</span> Central Nervous <span class="hlt">System</span> Lymphoma Located at Brain Stem in a Child</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Kim, Jinho</p> <p>2016-01-01</p> <p><span class="hlt">Primary</span> central nervous <span class="hlt">system</span> lymphoma (PCNSL) is an extranodal Non-Hodgkin's lymphoma that is confined to the brain, eyes, and/or leptomeninges without evidence of a <span class="hlt">systemic</span> <span class="hlt">primary</span> tumor. Although the tumor can affect all age groups, it is rare in childhood; thus, its incidence and prognosis in children have not been well defined and the best treatment strategy remains unclear. A nine-year old presented at our department with complaints of diplopia, dizziness, dysarthria, and right side hemiparesis. Magnetic resonance image suggested a diffuse brain stem glioma with infiltration into the right cerebellar peduncle. The patient was surgically treated by craniotomy and frameless stereotactic-guided biopsy, and unexpectedly, the histopathology of the mass was consistent with diffuse large B cell lymphoma, and immunohistochemical staining revealed positivity for CD20 and CD79a. Accordingly, we performed a staging work-up for <span class="hlt">systemic</span> lymphoma, but no evidence of lymphoma elsewhere in the body was obtained. In addition, she had a negative serologic finding for human immunodeficient virus, which confirmed the histopathological diagnosis of PCNSL. She was treated by radiosurgery at 12 Gy and subsequent adjuvant combination chemotherapy based on high dose methotrexate. Unfortunately, 10 months after the tissue-based diagnosis, she succumbed due to an acute hydrocephalic crisis. PMID:27867930</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3262465','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3262465"><span>Envisioning a Learning Health Care <span class="hlt">System</span>: The Electronic <span class="hlt">Primary</span> Care Research Network, A Case Study</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Delaney, Brendan C.; Peterson, Kevin A.; Speedie, Stuart; Taweel, Adel; Arvanitis, Theodoros N.; Hobbs, F. D. Richard</p> <p>2012-01-01</p> <p>PURPOSE The learning health care <span class="hlt">system</span> refers to the cycle of turning health care data into knowledge, translating that knowledge into practice, and creating new data by means of advanced information technology. The electronic <span class="hlt">Primary</span> Care Research Network (ePCRN) was a project, funded by the US National Institutes of Health, with the aim to facilitate clinical research using <span class="hlt">primary</span> care electronic health records (EHRs). METHODS We identified the requirements necessary to deliver clinical studies via a distributed electronic network linked to EHRs. After we explored a variety of informatics solutions, we constructed a functional prototype of the software. We then explored the barriers to adoption of the prototype software within US practice-based research networks. RESULTS We developed a <span class="hlt">system</span> to assist in the identification of eligible cohorts from EHR data. To preserve privacy, counts and flagging were performed remotely, and no data were transferred out of the EHR. A lack of batch export facilities from EHR <span class="hlt">systems</span> and ambiguities in the coding of clinical data, such as blood pressure, have so far prevented a full-scale deployment. We created an international consortium and a model for sharing further ePCRN development across a variety of ongoing projects in the United States and Europe. CONCLUSIONS A means of accessing health care data for research is not sufficient in itself to deliver a learning health care <span class="hlt">system</span>. EHR <span class="hlt">systems</span> need to use sophisticated tools to capture and preserve rich clinical context in coded data, and business models need to be developed that incentivize all stakeholders from clinicians to vendors to participate in the <span class="hlt">system</span>. PMID:22230831</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/10671022','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/10671022"><span>Measuring access to <span class="hlt">primary</span> medical care: some examples of the use of geographical information <span class="hlt">systems</span>.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Parker, E B; Campbell, J L</p> <p>1998-06-01</p> <p>This paper explores the potential for geographical information <span class="hlt">system</span> technology in defining some variables influencing the use of <span class="hlt">primary</span> care medical services. Eighteen general practices in Scotland contributed to a study examining the accessibility of their services and their patients' use of the local Accident and Emergency Department. Geo-referencing of information was carried out through analysis of postcode data relating to practices and patients. This information was analyzed using ARC/INFO GIS software in conjunction with the ORACLE relational database and 1991 census information. The results demonstrate that GIS technology has an important role in defining and analyzing the use of health services by the population.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.osti.gov/scitech/servlets/purl/1004961','SCIGOV-STC'); return false;" href="http://www.osti.gov/scitech/servlets/purl/1004961"><span>Thermal Analysis of the Divertor <span class="hlt">Primary</span> Heat Transfer <span class="hlt">System</span> Piping During the Gas Baking Process</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Yoder Jr, Graydon L; Harvey, Karen; Ferrada, Juan J</p> <p>2011-02-01</p> <p>A preliminary analysis has been performed examining the temperature distribution in the Divertor <span class="hlt">Primary</span> Heat Transfer <span class="hlt">System</span> (PHTS) piping and the divertor itself during the gas baking process. During gas baking, it is required that the divertor reach a temperature of 350 C. Thermal losses in the piping and from the divertor itself require that the gas supply temperature be maintained above that temperature in order to ensure that all of the divertor components reach the required temperature. The analysis described in this report was conducted in order to estimate the required supply temperature from the gas heater.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/15929034','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/15929034"><span>NOA-03 trial of high-dose methotrexate in <span class="hlt">primary</span> central nervous <span class="hlt">system</span> lymphoma: final report.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Herrlinger, Ulrich; Küker, Wilhelm; Uhl, Martin; Blaicher, Hans-Peter; Karnath, Hans-Otto; Kanz, Lothar; Bamberg, Michael; Weller, Michael</p> <p>2005-06-01</p> <p>The NOA-03 trial explored high-dose methotrexate alone in 37 patients with <span class="hlt">primary</span> central nervous <span class="hlt">system</span> lymphoma. The overall median survival was 25 months. After 4 years, the rate of leukoencephalopathy in patients surviving more than 12 months was 58% with and 10% without whole-brain radiotherapy given at relapse (p = 0.11). Attention deficits were found in all six tested patients, and memory deficits in four patients. Two patients had normal, three had moderately restricted, and one had markedly restricted quality of life. Thus, high-dose methotrexate with deferred radiotherapy had only moderate efficacy and was associated with significant neurotoxicity in long-term surviving patients.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2925331','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2925331"><span>Embedding effective depression care: using theory for <span class="hlt">primary</span> care organisational and <span class="hlt">systems</span> change</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p></p> <p>2010-01-01</p> <p> agreement is reached about how care is organised; and reflexive monitoring, which proposes that depression work requires agreement about how depression work will be monitored at the patient and practice level. We describe how these constructs can be used to guide the design and implementation of effective depression care in a way that can take account of contextual differences. Conclusions Ideas about what is required for an effective model and <span class="hlt">system</span> of depression care in <span class="hlt">primary</span> care need to be accompanied by theoretically informed frameworks that consider how these can be implemented. The conceptual framework we have presented can be used to guide organisational and <span class="hlt">system</span> change to develop common language around each construct between policy makers, service users, professionals, and researchers. This shared understanding across groups is fundamental to the effective implementation of change in <span class="hlt">primary</span> care for depression. PMID:20687962</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2011RJPCA..85...55K','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2011RJPCA..85...55K"><span>Peculiarities of the iron reduction mechanism in Fe-<span class="hlt">Al</span>-K <span class="hlt">system</span></span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Krylova, A. Yu.; Chernavskii, P. A.; Lyadov, A. S.; Sagitov, S. A.; Krylova, M. V.; Khadzhiev, S. N.</p> <p>2011-01-01</p> <p>Temperature-programmed reduction was used in combination with measurements of magnetization to determine the peculiarities of iron reduction in the Fe-K-<span class="hlt">Al</span> <span class="hlt">system</span>. It was found that reduction by hydrogen proceeds with the formation of metallic iron through the stage of magnetite formation (Fe3O4); the effective activation energies are 63 and 39 kJ/mol for the I and II stages, respectively. It was shown that substituting carbon oxide for hydrogen leads to iron reduction proceeding only to the stage of magnetite formation ( E Fe 3O4 = 94 kJ/mol). The magnetite interacts with CO to produce carbide (presumably Hegge carbide Fe2C). Iron reduction in the synthesis gas occurs with the preferential participation of hydrogen or carbon dioxide, depending on the rate of temperature rise.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2010MMTB...41..386Z','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2010MMTB...41..386Z"><span>Phase Equilibria Studies in the <span class="hlt">System</span> ZnO-``FeO''-<span class="hlt">Al</span>2O3-CaO-SiO2 Relevant to Imperial Smelting Furnace Slags: Part II</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Zhao, Baojun; Hayes, Peter C.; Jak, Evgueni</p> <p>2010-04-01</p> <p>The phase equilibria and the liquidus temperatures in the <span class="hlt">system</span> ZnO-“FeO”-<span class="hlt">Al</span>2O3-CaO-SiO2 have been determined experimentally in equilibrium with metallic iron. Specifically, the effects of <span class="hlt">Al</span>2O3 concentrations in Imperial Smelting Furnace slags are identified, and the results are presented in the form of pseudo-ternary sections ZnO-“FeO”-(<span class="hlt">Al</span>2O3 + CaO + SiO2) in which CaO/SiO2 = 0.93 and (CaO + SiO2)/<span class="hlt">Al</span>2O3 = 5.0 and 3.5, respectively. It was found that, in the presence of <span class="hlt">Al</span>2O3, the spinel phase is formed, the spinel <span class="hlt">primary</span> phase field expands, and the wustite and melilite <span class="hlt">primary</span> phase fields are reduced in size with an increasing <span class="hlt">Al</span>2O3 concentration. The implications of the findings to industrial practice are discussed.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2996385','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2996385"><span>Evaluation of computerized health management information <span class="hlt">system</span> for <span class="hlt">primary</span> health care in rural India</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p></p> <p>2010-01-01</p> <p>Background The Comprehensive Rural Health Services Project Ballabgarh, run by All India Institute of Medical Sciences (AIIMS), New Delhi has a computerized Health Management Information <span class="hlt">System</span> (HMIS) since 1988. The HMIS at Ballabgarh has undergone evolution and is currently in its third version which uses generic and open source software. This study was conducted to evaluate the effectiveness of a computerized Health Management Information <span class="hlt">System</span> in rural health <span class="hlt">system</span> in India. Methods The data for evaluation were collected by in-depth interviews of the stakeholders i.e. program managers (authors) and health workers. Health Workers from AIIMS and Non-AIIMS <span class="hlt">Primary</span> Health Centers were interviewed to compare the manual with computerized HMIS. A cost comparison between the two methods was carried out based on market costs. The resource utilization for both manual and computerized HMIS was identified based on workers' interviews. Results There have been no major hardware problems in use of computerized HMIS. More than 95% of data was found to be accurate. Health workers acknowledge the usefulness of HMIS in service delivery, data storage, generation of workplans and reports. For program managers, it provides a better tool for monitoring and supervision and data management. The initial cost incurred in computerization of two <span class="hlt">Primary</span> Health Centers was estimated to be Indian National Rupee (INR) 1674,217 (USD 35,622). Equivalent annual incremental cost of capital items was estimated as INR 198,017 (USD 4213). The annual savings is around INR 894,283 (USD 11,924). Conclusion The major advantage of computerization has been in saving of time of health workers in record keeping and report generation. The initial capital costs of computerization can be recovered within two years of implementation if the <span class="hlt">system</span> is fully operational. Computerization has enabled implementation of a good <span class="hlt">system</span> for service delivery, monitoring and supervision. PMID:21078203</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4499680','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4499680"><span>Development of a computerised decisions support <span class="hlt">system</span> for renal risk drugs targeting <span class="hlt">primary</span> healthcare</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Helldén, Anders; Al-Aieshy, Fadiea; Bastholm-Rahmner, Pia; Bergman, Ulf; Gustafsson, Lars L; Höök, Hans; Sjöviker, Susanne; Söderström, Anders; Odar-Cederlöf, Ingegerd</p> <p>2015-01-01</p> <p>Objectives To assess general practitioners (GPs) experience from the implementation and use of a renal computerised decision support <span class="hlt">system</span> (CDSS) for drug dosing, developed for <span class="hlt">primary</span> healthcare, integrated into the patient’s electronic health record (EHR), and building on estimation of the patient's creatinine clearance (ClCG). Design Qualitative research design by a questionnaire and a focus group discussion. Setting and participants Eight GPs at two <span class="hlt">primary</span> healthcare centres (PHCs). Interventions The GP at PHC 1, and the project group, developed and tested the technical solution of the CDSS. Proof-of-concept was tested by seven GPs at PHC 2. They also participated in a group discussion and answered a questionnaire. A web window in the EHR gave drug and dosage in relation to ClCG. Each advice was according to three principles: If? Why? Because. Outcome measures (1) The GPs’ experience of ‘easiness to use’ and ‘perceived usefulness’ at PHC 2, based on loggings of use, answers from a questionnaire using a 5-point Likert scale, and answers from a focus group discussion. (2) The number of patients aged 65 years and older with an estimation of ClCG before and after the implementation of the CDSS. Results The GPs found the CDSS fast, simple and easy to use. They appreciated the automatic presentation of the CICG status on opening the medication list, and the ability to actively look up specific drug recommendations in two steps. The CDSS scored high on the Likert scale. All GPs wanted to continue the use of the CDSS and to recommend it to others. The number of patients with an estimated ClCG increased 1.6-fold. Conclusions Acceptance of the simple graphical interface of this push and pull renal CDSS was high among the <span class="hlt">primary</span> care physicians evaluating this proof of concept. The graphical model should be useful for further development of renal decision support <span class="hlt">systems</span>. PMID:26150141</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26035344','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26035344"><span>NaF-KF-<span class="hlt">Al</span>F3 <span class="hlt">System</span>: Phase Transition in K2Na<span class="hlt">Al</span>3F12 Ternary Fluoride.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Kirik, Sergei D; Zaitseva, Yulia N; Leshok, Darya Yu; Samoilo, Alexandr S; Dubinin, Petr S; Yakimov, Igor S; Simakov, Dmitry A; Gusev, Alexandr O</p> <p>2015-06-15</p> <p>Phase formation in the NaF-KF-<span class="hlt">Al</span>F3 <span class="hlt">system</span>, in the vicinity of the K2Na<span class="hlt">Al</span>3F12 composition, has been studied. The samples have been prepared by melting the starting components at 650 °C. A new phase has been revealed, which appeared to be a low-temperature form of the well-known K2Na<span class="hlt">Al</span>3F12 ternary fluoride obtained by the hydrothermal synthesis method. The high-temperature form melts at 598 °C and is stable in a narrow temperature region of about 15 deg below the melting point. Thermal analysis, high temperature X-ray diffraction, IR-spectroscopy, X-ray fluorescence, and X-ray powder diffraction crystal structure analysis have been applied to study the composition, crystal structure, and thermal properties of the low-temperature phase. The crystal structure consists of trigonal-hexagonal two-dimensional (2D) grids built from the [<span class="hlt">Al</span>F6] octahedra connected via vertices. The 2D grids have a specific wave-like conformation with a wavelength of 11.88 Å and an amplitude of 0.46 Å. There is a shift of the adjacent grids relative to each other. Because of this shift, the space between the grids changes. The shift leads to the formation of pores adapted to potassium and sodium ions. The reasons for the wave-like structure of layers are discussed. It is shown that the two polymorphic forms differ in the order of cation occupations.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4789428','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4789428"><span>Recent Clinical Characteristics of Labors Using Three Japanese <span class="hlt">Systems</span> of Midwife-Led <span class="hlt">Primary</span> Delivery Care</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Suzuki, Shunji</p> <p>2016-01-01</p> <p>Objective. The objective of this study was to describe the recent clinical characteristics of labor using 3 <span class="hlt">systems</span> of Japanese midwife-led <span class="hlt">primary</span> delivery care, as follows: (1) those intending to give birth at home managed by midwives who do not belong to our hospital, (2) those planning to give birth in our hospital managed by the same midwives, and (3) those planning to give birth managed by midwives who belong to our hospital. Methods. A retrospective cohort study was performed. Results. There were no significant differences in the obstetric or neonatal outcomes among the 3 groups. The rate of transfers during labor with the <span class="hlt">system</span> involving midwives belonging to our hospital was higher than those with the other 2 <span class="hlt">systems</span>. In addition, the timing of transfers in the <span class="hlt">system</span> with the midwives belonging to our hospital was earlier than with the other 2 <span class="hlt">systems</span>. Among the 3 groups, there were no significant differences in the rate of the main 2 indications for transfers: fetal heart rate abnormality and failure to progress. Conclusion. There were no significant differences in perinatal outcomes among the 3 <span class="hlt">systems</span>; however, there were some differences in the status of transfers to obstetric shared care. PMID:27034827</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016JPSJ...85k4602N','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016JPSJ...85k4602N"><span>Crystallographic Features and State Stability of the Decagonal Quasicrystal in the <span class="hlt">Al</span>-Co-Cu Alloy <span class="hlt">System</span></span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Nakayama, Kei; Mizutani, Akito; Koyama, Yasumasa</p> <p>2016-11-01</p> <p>In the <span class="hlt">Al</span>-Co-Cu alloy <span class="hlt">system</span>, both the decagonal quasicrystal with the space group of Poverline{10}m2 and its approximant <span class="hlt">Al</span>13Co4 phase with monoclinic Cm symmetry are present around 20 at. % Co-10 at. % Cu. In this study, we examined the crystallographic features of prepared <span class="hlt">Al</span>-(30 - x) at. % Co-x at. % Cu samples mainly by transmission electron microscopy in order to make clear the crystallographic relation between the decagonal quasicrystal and the monoclinic <span class="hlt">Al</span>13Co4 structure. The results revealed a coexistence state consisting of decagonal quasicrystal and approximant <span class="hlt">Al</span>13Co4 regions in <span class="hlt">Al</span>-20 at. % Co-10 at. % Cu alloy samples. With the help of the coexistence state, the orientation relationship was established between the monoclinic <span class="hlt">Al</span>13Co4 structure and the decagonal quasicrystal. In the determined relationship, the crystallographic axis in the quasicrystal was found to be parallel to the normal direction of the (010)m plane in the <span class="hlt">Al</span>13Co4 structure, where the subscript m denotes the monoclinic <span class="hlt">system</span>. Based on data obtained experimentally, the state stability of the decagonal quasicrystal was also examined in terms of the Hume-Rothery (HR) mechanism on the basis of the nearly-free-electron approximation. It was found that a model based on the HR mechanism could explain the crystallographic features such as electron diffraction patterns and atomic arrangements found in the decagonal quasicrystal. In other words, the HR mechanism is most likely appropriate for the stability of the decagonal quasicrystal in the <span class="hlt">Al</span>-Co-Cu alloy <span class="hlt">system</span>.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2614732','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2614732"><span>Postperovskite phase equilibria in the MgSiO3–<span class="hlt">Al</span>2O3 <span class="hlt">system</span></span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Tsuchiya, Jun; Tsuchiya, Taku</p> <p>2008-01-01</p> <p>We investigate high-P,T phase equilibria of the MgSiO3–<span class="hlt">Al</span>2O3 <span class="hlt">system</span> by means of the density functional ab initio computation methods with multiconfiguration sampling. Being different from earlier studies based on the static substitution properties with no consideration of Rh2O3(II) phase, present calculations demonstrate that (i) dissolving <span class="hlt">Al</span>2O3 tends to decrease the postperovskite transition pressure of MgSiO3 but the effect is not significant (≈-0.2 GPa/mol% <span class="hlt">Al</span>2O3); (ii) <span class="hlt">Al</span>2O3 produces the narrow perovskite+postperovskite coexisting P,T area (≈1 GPa) for the pyrolitic concentration (x<span class="hlt">Al</span>2O3 ≈6 mol%), which is sufficiently responsible to the deep-mantle D″ seismic discontinuity; (iii) the transition would be smeared (≈4 GPa) for the basaltic <span class="hlt">Al</span>-rich composition (x<span class="hlt">Al</span>2O3 ≈20 mol%), which is still seismically visible unless iron has significant effects; and last (iv) the perovskite structure spontaneously changes to the Rh2O3(II) with increasing the <span class="hlt">Al</span> concentration involving small displacements of the Mg-site cations. PMID:19036928</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25245922','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25245922"><span>Isolated <span class="hlt">primary</span> central nervous <span class="hlt">system</span> lymphoma arising from the optic chiasm.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Vassal, F; Pommier, B; Boutet, C; Forest, F; Campolmi, N; Nuti, C</p> <p>2014-12-01</p> <p>A 58-year-old previously healthy woman rapidly developed progressive bilateral visual loss. Magnetic resonance imaging revealed a bulging appearance of the optic chiasm, with homogeneous enhancement after gadolinium administration, which suggested an optic glioma or inflammatory disease. In the absence of (para)clinical clues for a specific diagnosis despite extensive investigation, a biopsy of one optic nerve was performed, resulting in a diagnosis of non-Hodgkin B-cell lymphoma. There was no evidence of any other ocular or <span class="hlt">systemic</span> involvement, therefore the conclusion was that this immunocompetent patient had a <span class="hlt">primary</span> central nervous <span class="hlt">system</span> lymphoma isolated in the anterior visual pathway. Treatment included two cycles of polychemotherapy (rituximab, methotrexate, carmustine, etoposide, methylprednisolone), followed by autologous peripheral blood stem cell transplantation and rituximab plus cytarabine consolidation therapy. Subsequently, the patient exhibited significant improvement in vision, and was still disease-free at the 1-year follow-up examination. The aim of the present paper was to provide well-documented clinical, radiological, and intraoperative features of isolated <span class="hlt">primary</span> malignant lymphoma arising from the anterior visual pathway. A better recognition of this rare pathological entity is necessary for clinicians who may encounter similar presentations, as prompt management is crucial for both a visual and vital prognosis.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/scitech/biblio/1031524','SCIGOV-STC'); return false;" href="https://www.osti.gov/scitech/biblio/1031524"><span>Modeling and Simulation of the ITER First Wall/Blanket <span class="hlt">Primary</span> Heat Transfer <span class="hlt">System</span></span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Ying, Alice; Popov, Emilian L</p> <p>2011-01-01</p> <p>ITER inductive power operation is modeled and simulated using a thermal-hydraulics <span class="hlt">system</span> code (RELAP5) integrated with a 3-D CFD (SC-Tetra) code. The <span class="hlt">Primary</span> Heat Transfer <span class="hlt">System</span> (PHTS) functions are predicted together with the main parameters operational ranges. The control algorithm strategy and derivation are summarized as well. The First Wall and Blanket modules are the <span class="hlt">primary</span> components of PHTS, used to remove the major part of the thermal heat from the plasma. The modules represent a set of flow channels in solid metal structure that serve to absorb the radiation heat and nuclear heating from the fusion reactions and to provide shield for the vacuum vessel. The blanket modules are water cooled. The cooling is forced convective with constant blanket inlet temperature and mass flow rate. Three independent water loops supply coolant to the three blanket sectors. The main equipment of each loop consists of a pump, a steam pressurizer and a heat exchanger. A major feature of ITER is the pulsed operation. The plasma does not burn continuously, but on intervals with large periods of no power between them. This specific feature causes design challenges to accommodate the thermal expansion of the coolant during the pulse period and requires active temperature control to maintain a constant blanket inlet temperature.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28241672','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28241672"><span>Structural Behaviour of Solid Solutions in the Nd<span class="hlt">Al</span>O3-SrTiO3 <span class="hlt">System</span>.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Ohon, Natalia; Stepchuk, Roman; Blazhivskyi, Kostiantyn; Vasylechko, Leonid</p> <p>2017-12-01</p> <p>Single-phase mixed aluminates-titanates Nd1-x Sr x <span class="hlt">Al</span>1-x Ti x O3 (x = 0.3 ÷ 0.9) were prepared from stoichiometric amounts of constituent oxides Nd2O3, <span class="hlt">Al</span>2O3, TiO2 and strontium carbonate SrCO3 by solid-state reaction technique in air at 1773 K. Crystal structure parameters of Nd1-x Sr x <span class="hlt">Al</span>1-x Ti x O3 were refined by full-profile Rietveld refinement in space groups R [Formula: see text] c (x = 0.3, 0.5, 0.7 and 0.8) and Pm [Formula: see text] m (x = 0.9). Comparison of the obtained structural parameters with the literature data for the end members of the <span class="hlt">system</span> Nd<span class="hlt">Al</span>O3 and SrTiO3 revealed formation of two kinds of solid solutions Nd1-xSrx<span class="hlt">Al</span>1-xTixO3 with the cubic and rhombohedral perovskite structure. Morphotropic rhombohedral-to-cubic phase transition in Nd1-xSrx<span class="hlt">Al</span>1-xTixO3 series occurs at x = 0.84. Based on the results obtained as well as the literature data for the parent compounds, the tentative phase diagram of the Nd<span class="hlt">Al</span>O3-SrTiO3 pseudo-binary <span class="hlt">system</span> have been constructed.</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_14");'>14</a></li> <li><a href="#" onclick='return showDiv("page_15");'>15</a></li> <li class="active"><span>16</span></li> <li><a href="#" onclick='return showDiv("page_17");'>17</a></li> <li><a href="#" onclick='return showDiv("page_18");'>18</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_16 --> <div id="page_17" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_15");'>15</a></li> <li><a href="#" onclick='return showDiv("page_16");'>16</a></li> <li class="active"><span>17</span></li> <li><a href="#" onclick='return showDiv("page_18");'>18</a></li> <li><a href="#" onclick='return showDiv("page_19");'>19</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="321"> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017NRL....12..148O','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017NRL....12..148O"><span>Structural Behaviour of Solid Solutions in the Nd<span class="hlt">Al</span>O3-SrTiO3 <span class="hlt">System</span></span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Ohon, Natalia; Stepchuk, Roman; Blazhivskyi, Kostiantyn; Vasylechko, Leonid</p> <p>2017-02-01</p> <p>Single-phase mixed aluminates-titanates Nd1- x Sr x <span class="hlt">Al</span>1- x Ti x O3 ( x = 0.3 ÷ 0.9) were prepared from stoichiometric amounts of constituent oxides Nd2O3, <span class="hlt">Al</span>2O3, TiO2 and strontium carbonate SrCO3 by solid-state reaction technique in air at 1773 K. Crystal structure parameters of Nd1- x Sr x <span class="hlt">Al</span>1- x Ti x O3 were refined by full-profile Rietveld refinement in space groups R overline{3} c ( x = 0.3, 0.5, 0.7 and 0.8) and Pm overline{3} m ( x = 0.9). Comparison of the obtained structural parameters with the literature data for the end members of the <span class="hlt">system</span> Nd<span class="hlt">Al</span>O3 and SrTiO3 revealed formation of two kinds of solid solutions Nd1-xSrx<span class="hlt">Al</span>1-xTixO3 with the cubic and rhombohedral perovskite structure. Morphotropic rhombohedral-to-cubic phase transition in Nd1-xSrx<span class="hlt">Al</span>1-xTixO3 series occurs at x = 0.84. Based on the results obtained as well as the literature data for the parent compounds, the tentative phase diagram of the Nd<span class="hlt">Al</span>O3-SrTiO3 pseudo-binary <span class="hlt">system</span> have been constructed.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/scitech/biblio/1076718','SCIGOV-STC'); return false;" href="https://www.osti.gov/scitech/biblio/1076718"><span>Distributed Hierarchical Control of Multi-Area Power <span class="hlt">Systems</span> with Improved <span class="hlt">Primary</span> Frequency Regulation</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Lian, Jianming; Marinovici, Laurentiu D.; Kalsi, Karanjit; Du, Pengwei; Elizondo, Marcelo A.</p> <p>2012-12-12</p> <p>The conventional distributed hierarchical control architecture for multi-area power <span class="hlt">systems</span> is revisited. In this paper, a new distributed hierarchical control architecture is proposed. In the proposed architecture, pilot generators are selected in each area to be equipped with decentralized robust control as a supplementary to the conventional droop speed control. With the improved <span class="hlt">primary</span> frequency control, the <span class="hlt">system</span> frequency can be restored to the nominal value without the help of secondary frequency control, which reduces the burden of the automatic generation control for frequency restoration. Moreover, the low frequency inter-area electromechanical oscillations can also be effectively damped. The effectiveness of the proposed distributed hierarchical control architecture is validated through detailed simulations.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/24356697','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/24356697"><span>[Health situation assessment by <span class="hlt">primary</span> care workers based on geographic information <span class="hlt">systems</span>].</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Ritter, Fernando; Rosa, Roger dos Santos; Flores, Rui</p> <p>2013-12-01</p> <p><span class="hlt">Primary</span> healthcare has made little use of information <span class="hlt">systems</span> to assess the population's health situation due to the difficulty in understanding the reports. Generic definitions of actions are common, based on empirical observations. The current study aimed to evaluate whether the introduction of georeferenced indicators can serve to better identify individuals' health situation, which would help planning actions by health teams. Healthcare workers from eight teams answered a questionnaire at three different moments: the first, before reading the information <span class="hlt">system</span>'s reports; the second after reading; and the third after using georeferencing. The results showed a significant difference in the classification of the health situation using georeferencing when compared to the previous moments (p < 0.05). Georeferencing facilitated analysis of the health situation, fostering better monitoring of work processes. Finally, use of the data points to rationalization of actions and possible upgrading of healthcare. The study suggests the use of georeferencing in the work agenda to become an effective tool for orienting actions.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4558226','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4558226"><span>Genome-wide analysis uncovers novel recurrent alterations in <span class="hlt">primary</span> central nervous <span class="hlt">system</span> lymphomas</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Braggio, Esteban; Van Wier, Scott; Ojha, Juhi; McPhail, Ellen; Asmann, Yan W.; Egan, Jan; da Silva, Jackline Ayres; Schiff, David; Lopes, M Beatriz; Decker, Paul A; Valdez, Riccardo; Tibes, Raoul; Eckloff, Bruce; Witzig, Thomas E.; Stewart, A Keith; Fonseca, Rafael; O’Neill, Brian Patrick</p> <p>2015-01-01</p> <p>Purpose <span class="hlt">Primary</span> central nervous <span class="hlt">system</span> lymphoma (PCNSL) is an aggressive non-Hodgkin lymphoma confined to the CNS. Whether there is a PCNSL-specific genomic signature and, if so, how it differs from <span class="hlt">systemic</span> diffuse large B-cell lymphoma (DLBCL) is uncertain. Experimental design We performed a comprehensive genomic study of tumor samples from 19 immunocompetent PCNSL patients. Testing comprised array-comparative genomic hybridization and whole exome sequencing. Results Biallelic inactivation of TOX and PRKCD were recurrently found in PCNSL but not in <span class="hlt">systemic</span> DLBCL, suggesting a specific role in PCNSL pathogenesis. Additionally, we found a high prevalence of MYD88 mutations (79%) and CDKN2A biallelic loss (60%). Several genes recurrently affected in PCNSL were common with <span class="hlt">systemic</span> DLBCL, including loss of TNFAIP3, PRDM1, GNA13, TMEM30A, TBL1XR1, B2M, CD58, activating mutations of CD79B, CARD11 and translocations IgH-BCL6. Overall, BCR/TLR/NF-κB pathways were altered in >90% of PNCSL, highlighting its value for targeted therapeutic approaches. Furthermore, integrated analysis showed enrichment of pathways associated with immune response, proliferation, apoptosis, and lymphocyte differentiation. Conclusions In summary, genome-wide analysis uncovered novel recurrent alterations, including TOX and PRKCD, helping to differentiate PCNSL from <span class="hlt">systemic</span> DLBCL and related lymphomas. PMID:25991819</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/24354510','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/24354510"><span>The activation pattern of macrophages in giant cell (temporal) arteritis and <span class="hlt">primary</span> angiitis of the central nervous <span class="hlt">system</span>.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Mihm, Bernhard; Bergmann, Markus; Brück, Wolfgang; Probst-Cousin, Stefan</p> <p>2014-06-01</p> <p>To determine if the pattern of macrophage activation reflects differences in the pathogenesis and clinical presentation of giant cell arteritis and <span class="hlt">primary</span> angiitis of the central nervous <span class="hlt">system</span>, specimens of 10 patients with giant cell arteritis and five with <span class="hlt">primary</span> angiitis of the central nervous <span class="hlt">system</span> were immunohistochemically studied and the expression of the macrophage activation markers 27E10, MRP14, MRP8 and 25F9 was determined in the vasculitic infiltrates. Thus, a partly different expression pattern of macrophage activation markers in giant cell arteritis and <span class="hlt">primary</span> angiitis of the central nervous <span class="hlt">system</span> was observed. The group comparison revealed that giant cell arteritis cases had significantly higher numbers of acute activated MRP14-positive macrophages, whereas <span class="hlt">primary</span> angiitis of the central nervous <span class="hlt">system</span> is characterized by a tendency toward more MRP8-positive intermediate/late activated macrophages. Furthermore, in giant cell arteritis comparably fewer CD8-positive lymphocytes were observed. These observations suggest, that despite their histopathological similarities, giant cell arteritis and <span class="hlt">primary</span> angiitis of the central nervous <span class="hlt">system</span> appear to represent either distinct entities within the spectrum of granulomatous vasculitides or different stages of similar disease processes. Their discrete clinical presentation is reflected by different activation patterns of macrophages, which may characterize giant cell arteritis as a more acute process and <span class="hlt">primary</span> angiitis of the central nervous <span class="hlt">system</span> as a more advanced inflammatory process.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/1988MTA....19.1645A','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/1988MTA....19.1645A"><span>Microstructural characterization of the dispersed phases in <span class="hlt">Al</span>-Ce-Fe <span class="hlt">system</span></span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Ayer, Raghavan; Angers, L. M.; Mueller, R. R.; Scanlon, J. C.; Klein, C. F.</p> <p>1988-07-01</p> <p>Analytical electron microscopy studies were conducted on a rapidly solidified <span class="hlt">Al</span>-8.8Fe-3.7Ce alloy and arc melted buttons of aluminum rich <span class="hlt">Al</span>-Fe-Ce alloys to determine the characteristics of the metastable and equilibrium phases. The rapidly solidified alloy consisted of binary and ternary metastable phases in the as-extruded condition. The binary metastable phase was identified to be <span class="hlt">Al</span>6Fe, while the ternary metastable phases were identified to be <span class="hlt">Al</span>10Fe2Ce and <span class="hlt">Al</span>20Fe5Ce. The <span class="hlt">Al</span>20Fe5Ce was a decagonal quasicrystal while the <span class="hlt">Al</span>10Fe2Ce phase was determined to have an orthorhombic crystal structure belonging to space group Cmmm, Cmm2, or C222. Microscopy studies of RS alloy and cast buttons annealed at 700 K established the equilibrium phases to be <span class="hlt">Al</span>13Fe4, <span class="hlt">Al</span>4Ce, and an <span class="hlt">Al</span>13Fe3Ce ternary phase which was first identified in the present study. The crystal structure of the equilibrium ternary phase was determined to be orthorhombic with a Cmcm or Cmc2 space group. The details of X-ray microanalysis and convergent beam electron diffraction analysis are described.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/pages/biblio/1340510-sensitivity-polycrystal-local-plasticity-slip-system-kinematic-hardening-laws-al-t6','SCIGOV-DOEP'); return false;" href="https://www.osti.gov/pages/biblio/1340510-sensitivity-polycrystal-local-plasticity-slip-system-kinematic-hardening-laws-al-t6"><span>Sensitivity of polycrystal [local] plasticity to slip <span class="hlt">system</span> kinematic hardening laws for <span class="hlt">Al</span> 7075-T6</span></a></p> <p><a target="_blank" href="http://www.osti.gov/pages">DOE PAGES</a></p> <p>Hennessey, Conor; Castelluccio, Gustavo M.; McDowell, David L.</p> <p>2017-01-22</p> <p>The prediction of formation and early growth of microstructurally small fatigue cracks requires use of constitutive models that accurately estimate local states of stress, strain, and cyclic plastic strain. However, few research efforts have attempted to systematically consider the sensitivity of overall cyclic stress-strain hysteresis and higher order mean stress relaxation and plastic strain ratcheting responses introduced by the slip <span class="hlt">system</span> back-stress formulation in crystal plasticity, even for face centered cubic (FCC) crystal <span class="hlt">systems</span>. This paper explores the performance of two slip <span class="hlt">system</span> level kinematic hardening models using a finite element crystal plasticity implementation as a User Material Subroutine (UMAT)more » within ABAQUS, with fully implicit numerical integration. The two kinematic hardening formulations aim to reproduce the cyclic deformation of polycrystalline <span class="hlt">Al</span> 7075-T6 in terms of both macroscopic cyclic stress-strain hysteresis loop shape, as well as ratcheting and mean stress relaxation under strain- or stress-controlled loading with mean strain or stress, respectively. The first formulation is an Armstrong-Frederick type hardening-dynamic recovery law for evolution of the back stress. This approach is capable of reproducing observed deformation under completely reversed uniaxial loading conditions, but overpredicts the rate of cyclic ratcheting and associated mean stress relaxation. The second formulation corresponds to a multiple back stress Ohno-Wang type hardening law with nonlinear dynamic recovery. The adoption of this back stress evolution law greatly improves the capability to model experimental results for polycrystalline specimens subjected to cycling with mean stress or strain. As a result, the relation of such nonlinear dynamic recovery effects are related to slip <span class="hlt">system</span> interactions with dislocation substructures.« less</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/pages/biblio/1340510-sensitivity-polycrystal-plasticity-slip-system-kinematic-hardening-laws-al-t6','SCIGOV-DOEP'); return false;" href="https://www.osti.gov/pages/biblio/1340510-sensitivity-polycrystal-plasticity-slip-system-kinematic-hardening-laws-al-t6"><span>Sensitivity of polycrystal plasticity to slip <span class="hlt">system</span> kinematic hardening laws for <span class="hlt">Al</span> 7075-T6</span></a></p> <p><a target="_blank" href="http://www.osti.gov/pages">DOE PAGES</a></p> <p>Hennessey, Conor; Castelluccio, Gustavo M.; McDowell, David L.</p> <p>2017-02-01</p> <p>The prediction of formation and early growth of microstructurally small fatigue cracks requires use of constitutive models that accurately estimate local states of stress, strain, and cyclic plastic strain. However, few research efforts have attempted to systematically consider the sensitivity of overall cyclic stress-strain hysteresis and higher order mean stress relaxation and plastic strain ratcheting responses introduced by the slip <span class="hlt">system</span> back-stress formulation in crystal plasticity, even for face centered cubic (FCC) crystal <span class="hlt">systems</span>. This paper explores the performance of two slip <span class="hlt">system</span> level kinematic hardening models using a finite element crystal plasticity implementation as a User Material Subroutine (UMAT)more » within ABAQUS, with fully implicit numerical integration. The two kinematic hardening formulations aim to reproduce the cyclic deformation of polycrystalline <span class="hlt">Al</span> 7075-T6 in terms of both macroscopic cyclic stress-strain hysteresis loop shape, as well as ratcheting and mean stress relaxation under strain- or stress-controlled loading with mean strain or stress, respectively. The first formulation is an Armstrong-Frederick type hardening-dynamic recovery law for evolution of the back stress. This approach is capable of reproducing observed deformation under completely reversed uniaxial loading conditions, but overpredicts the rate of cyclic ratcheting and associated mean stress relaxation. The second formulation corresponds to a multiple back stress Ohno-Wang type hardening law with nonlinear dynamic recovery. The adoption of this back stress evolution law greatly improves the capability to model experimental results for polycrystalline specimens subjected to cycling with mean stress or strain. As a result, the relation of such nonlinear dynamic recovery effects are related to slip <span class="hlt">system</span> interactions with dislocation substructures.« less</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://files.eric.ed.gov/fulltext/EJ1008869.pdf','ERIC'); return false;" href="http://files.eric.ed.gov/fulltext/EJ1008869.pdf"><span>Exploring Online Learning at <span class="hlt">Primary</span> Schools: Students' Perspectives on Cyber Home Learning <span class="hlt">System</span> through Video Conferencing (CHLS-VC)</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Lee, June; Yoon, Seo Young; Lee, Chung Hyun</p> <p>2013-01-01</p> <p>The purposes of the study are to investigate CHLS (Cyber Home Learning <span class="hlt">System</span>) in online video conferencing environment in <span class="hlt">primary</span> school level and to explore the students' responses on CHLS-VC (Cyber Home Learning <span class="hlt">System</span> through Video Conferencing) in order to explore the possibility of using CHLS-VC as a supportive online learning <span class="hlt">system</span>. The…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25400782','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25400782"><span>Clinicopathological and immunohistochemical features of <span class="hlt">primary</span> central nervous <span class="hlt">system</span> germ cell tumors: a 24-years experience.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Gao, Yuping; Jiang, Jiyao; Liu, Qiang</p> <p>2014-01-01</p> <p><span class="hlt">Primary</span> central nervous <span class="hlt">system</span> (CNS) germ cell tumors (GCTs) are a rare heterogeneous group of lesions, which the clinicopathological features have a marked degree of heterogeneity comparing with that of gonadal GCTs. Accurately diagnosing CNS GCTs might be extremely difficult and requires immunohistochemical verification. This study was to investigate the biological feature of CNS GCTs and diagnostic value of immunohistochemical markers OCT3/4, C-kit, PLAP, and CD30 in CNS GCTs. A retrospective study was performed on 34 patients with CNS germ cell tumors between 1990 and 2014. 34 CNS GCTs account for 9.2% of all <span class="hlt">primary</span> CNS neoplasms. The sellar region (35.3%) and pineal gland (17.6%) were the most common sites of intracranial GCTs. Hydrocephalus (82.4%) and diplopia (46.9%) were the two most common clinical presentations. The most common histological subtypes were germinoma (67.6%). PLAP, c-kit, OCT3/4 were highly expressed in gernimomas. CD30 and CK AE1/3 stainings were positive in embryonal carcinoma. Yolk sac tumor component showed positive staining for AFP and CK AE1/3. β-HCG staining was positive in choriocarcinoma and STGC. Patients with mature teratomas and germinomas had a better prognosis (a 5-year survival rate) than those with embryonal carcinoma and choriocarcinoma (a 5-year survival rates were 0). Our finding suggest that the incidences of <span class="hlt">primary</span> CNS GCTs are higher in South China than in the West, but mixed GCTs are uncommon in our study. The judicious use of a panel of selected markers is helpful in diagnosing and predicting the prognosis for CNS GCTs.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/scitech/biblio/22412999','SCIGOV-STC'); return false;" href="https://www.osti.gov/scitech/biblio/22412999"><span>Quasiperiodic <span class="hlt">Al</span>GaAs superlattices for neuromorphic networks and nonlinear control <span class="hlt">systems</span></span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Malyshev, K. V.</p> <p>2015-01-28</p> <p>The application of quasiperiodic <span class="hlt">Al</span>GaAs superlattices as a nonlinear element of the FitzHugh–Nagumo neuromorphic network is proposed and theoretically investigated on the example of Fibonacci and figurate superlattices. The sequences of symbols for the figurate superlattices were produced by decomposition of the Fibonacci superlattices' symbolic sequences. A length of each segment of the decomposition was equal to the corresponding figurate number. It is shown that a nonlinear network based upon Fibonacci and figurate superlattices provides better parallel filtration of a half-tone picture; then, a network based upon traditional diodes which have cubic voltage-current characteristics. It was found that the figurate superlattice F{sup 0}{sub 11}(1) as a nonlinear network's element provides the filtration error almost twice less than the conventional “cubic” diode. These advantages are explained by a wavelike shape of the decreasing part of the quasiperiodic superlattice's voltage-current characteristic, which leads to multistability of the network's cell. This multistability promises new interesting nonlinear dynamical phenomena. A variety of wavy forms of voltage-current characteristics opens up new interesting possibilities for quasiperiodic superlattices and especially for figurate superlattices in many areas—from nervous <span class="hlt">system</span> modeling to nonlinear control <span class="hlt">systems</span> development.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2013NIMPA.721...21S','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2013NIMPA.721...21S"><span>Thick target neutron yield from 145 MeV 19F+27<span class="hlt">Al</span> <span class="hlt">system</span></span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Sunil, C.; Bandyopadhyay, T.; Nandy, M.; Suman, Vitisha; Paul, S.; Nanal, V.; Pillay, R. G.; Sarkar, P. K.</p> <p>2013-09-01</p> <p>The double differential neutron energy distribution has been measured for the 19F+27<span class="hlt">Al</span> <span class="hlt">system</span> at 145 MeV projectile energy. The time of flight technique was used to measure the energy while pulse shape discrimination has been used to separate the neutrons from photons. The results are compared with the statistical nuclear reaction model codes PACE and EMPIRE. The PACE code appears to predict the slope and the end point energy of the experimental spectra fairly well but over predicts the values. The slope obtained from the EMPIRE calculations appears to be harder while the values being closer to the experimental results. The yield from the Hauser-Feshbach based compound nucleus model calculations agree reasonably well with the experimental results at the backward angles but not in the forward directions. The energy integrated angular distribution from 145 MeV projectiles show an enhanced emission in the forward angles compared to the similar results from 110 MeV projectiles. This analysis suggests some contribution from the pre-equilibrium emissions from the <span class="hlt">system</span> at the higher projectile energy.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015JAP...117d4303M','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015JAP...117d4303M"><span>Quasiperiodic <span class="hlt">Al</span>GaAs superlattices for neuromorphic networks and nonlinear control <span class="hlt">systems</span></span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Malyshev, K. V.</p> <p>2015-01-01</p> <p>The application of quasiperiodic <span class="hlt">Al</span>GaAs superlattices as a nonlinear element of the FitzHugh-Nagumo neuromorphic network is proposed and theoretically investigated on the example of Fibonacci and figurate superlattices. The sequences of symbols for the figurate superlattices were produced by decomposition of the Fibonacci superlattices' symbolic sequences. A length of each segment of the decomposition was equal to the corresponding figurate number. It is shown that a nonlinear network based upon Fibonacci and figurate superlattices provides better parallel filtration of a half-tone picture; then, a network based upon traditional diodes which have cubic voltage-current characteristics. It was found that the figurate superlattice F011(1) as a nonlinear network's element provides the filtration error almost twice less than the conventional "cubic" diode. These advantages are explained by a wavelike shape of the decreasing part of the quasiperiodic superlattice's voltage-current characteristic, which leads to multistability of the network's cell. This multistability promises new interesting nonlinear dynamical phenomena. A variety of wavy forms of voltage-current characteristics opens up new interesting possibilities for quasiperiodic superlattices and especially for figurate superlattices in many areas—from nervous <span class="hlt">system</span> modeling to nonlinear control <span class="hlt">systems</span> development.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/scitech/biblio/21090856','SCIGOV-STC'); return false;" href="https://www.osti.gov/scitech/biblio/21090856"><span>Bronchial Artery and <span class="hlt">Systemic</span> Artery Embolization in the Management of <span class="hlt">Primary</span> Lung Cancer Patients with Hemoptysis</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Park, Hong Suk Kim, Young Il; Kim, Hyae Young; Zo, Jae-Ill; Lee, Joo Hyuk; Lee, Jin Soo</p> <p>2007-07-15</p> <p>Purpose. To assess the safety and effectiveness of arterial embolization in lung cancer patients with hemoptysis. Methods. Nineteen <span class="hlt">primary</span> lung cancer patients with hemoptysis underwent bronchial artery and <span class="hlt">systemic</span> artery embolization from April 2002 to March 2005. There were 17 men and 2 women, with a mean age of 59 years. Histologic analysis revealed squamous cell carcinoma in 10 patients and poorly differentiated adenocarcinoma in 9 patients. The amount of hemoptysis was bleeding of 25-50 ml within 24 hr in 8 patients, recurrent blood-tinged sputum in 6, and bleeding of 100 ml or more per 24 hr in 5. Embolization was done with a superselective technique using a microcatheter and polyvinyl alcohol particles to occlude the affected vessels. Results. Arterial embolization was technically successful in all patients and clinically successful in 15 patients (79%). The average number of arteries embolized was 1.2. Bronchial arteriography revealed staining (all patients), dilatation of the artery or hypervascularity (10 patients), and bronchopulmonary shunt (6 patients). The recurrence rate was 33% (5/15) and 11 patients were alive with a mean follow-up time of 148 days (30-349 days). Conclusion. Arterial embolotherapy for hemoptysis in patients with <span class="hlt">primary</span> lung cancer is an effective, safe therapeutic modality despite the fact the vascular changes are subtle on angiography.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/22165652','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/22165652"><span>Patient-centered medical home: an emerging <span class="hlt">primary</span> care model and the military health <span class="hlt">system</span>.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Marshall, Robert C; Doperak, Martin; Milner, Michelle; Motsinger, Charles; Newton, Terry; Padden, Maureen; Pastoor, Sara; Hughes, Cortney L; LeFurgy, Jennifer; Mun, Seong K</p> <p>2011-11-01</p> <p>The patient-centered medical home (PCMH) is a <span class="hlt">primary</span> care model that aims to provide quality care that is coordinated, comprehensive, and cost-effective. PCMH is hinged upon building a strong patient-provider relationship and using a team-based approach to care to increase continuity and access. It is anticipated that PCMH can curb the growth of health care costs through better preventative medicine and lower utilization of services. The Navy, Air Force, and Army are implementing versions of PCMH, which includes the use of technologies for improved documentation, better disease management, improved communication between the care teams and patients, and increased access to care. This article examines PCMH in the Military Health <span class="hlt">System</span> by providing examples of the transition from each of the branches. The authors argue that the military must overcome unique challenges to implement and sustain PCMH that civilian providers may not face because of the deployment of patients and staff, the military's mission of readiness, and the use of both on-base and off-base care by beneficiaries. Our objective is to lay out these considerations and to provide ways that they have been or can be addressed within the transition from traditional <span class="hlt">primary</span> care to PCMH.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/20034728','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/20034728"><span>Performance of newly implemented Environmental Management <span class="hlt">Systems</span> in <span class="hlt">primary</span> schools in South Africa.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Hens, Luc; Wiedemann, Torsten; Raath, Schalk; Stone, Riana; Renders, Paul; Craenhals, Eric</p> <p>2010-01-01</p> <p>Quantitative results from Environmental Management <span class="hlt">Systems</span> (EMS) at <span class="hlt">primary</span> schools have rarely been examined in literature. This paper presents the monitoring results of environmental care in 39 <span class="hlt">primary</span> schools in Northern South Africa. During 2 years, after the EMS was implemented in the curriculum and in the school's management, the progress of environmental performances of the participating schools has been measured, by means of detailed questionnaires, related to four environmental aspects: water, waste, energy and greening. At the beginning of the project, 50% of the schools performed well on water-related environmental actions. Two years later it was 76%. For waste-related activities the improvement was even stronger: from 50% to 100%. The environmental performances of the schools improved also for greening-related actions, from 50% at the start of the project to 64% two years later. Only energy-related activities did not improve significantly with only 24% of all schools performing well at the end of the survey period. In general, the introduction of an EMS succeeded in an improvement of the overall environmental performances of the schools, but cost-intensive activities were less successful than others.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/21840220','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/21840220"><span><span class="hlt">Primary</span> activity measurements with a 4πβ-4πγ coincidence counting <span class="hlt">system</span>.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Nedjadi, Youcef; Bailat, Claude J; Bochud, François O</p> <p>2012-01-01</p> <p>The radioactive concentrations of (166m)Ho, (134)Cs and (133)Ba solutions have been standardised using a 4πβ-4πγ coincidence counting <span class="hlt">system</span> we have recently set up. The detection in the beta channel is performed using various geometries of a UPS-89 plastic scintillator optically coupled to a selected low-noise 1in. diameter photomultiplier tube. The light-tight thin capsule that encloses this beta detector is housed within the well of a 5in.×5in. NaI(Tl) monocrystal detector. The beta detection efficiency can be varied either by optical filtering or electronic discrimination when the electrons loose all their energy in the plastic scintillator. This 4πβ-4πγ coincidence <span class="hlt">system</span> improves on our 4πβ(PC)-γ <span class="hlt">system</span> in that its sample preparation is less labour intensive, it yields larger beta- and gamma-counting efficiencies thus enabling the standardisation of low activity sources with good statistics in reasonable time, and it makes standardising short-lived radionuclides easier. The resulting radioactive concentrations of (166m)Ho, (134)Cs and (133)Ba are found to agree with those measured with other <span class="hlt">primary</span> measurement methods thus validating our 4πβ-4πγ coincidence counting <span class="hlt">system</span>.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28375369','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28375369"><span>Comparison of degradation and recaesiation between GaAs and <span class="hlt">Al</span>GaAs photocathodes in an unbaked vacuum <span class="hlt">system</span>.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Feng, Cheng; Zhang, Yijun; Shi, Feng; Qian, Yunsheng; Cheng, Hongchang; Zhang, Junju; Liu, Xinxin; Zhang, Xiang</p> <p>2017-03-20</p> <p>The lifetime and reliability of a photocathode during operation are always raised problems and the photocathode performance depends on the vacuum condition. With the purpose of investigating the stability and reliability of a GaAs-based photocathode in a harsher vacuum environment, reflection-mode exponential-doped GaAs and <span class="hlt">Al</span>GaAs photocathodes are metalorganic vapor-phase epitaxial grown and then (Cs, O) activated inside an unbaked vacuum chamber. The degraded photocurrents are compared after activation and recaesiations between GaAs and <span class="hlt">Al</span>GaAs photocathdoes under illumination with an equal initial photocurrent and an equal optical flux, respectively. It is found that the performance on degradation and recaesiations between GaAs and <span class="hlt">Al</span>GaAs photocathodes are different. In the unbaked vacuum <span class="hlt">system</span>, the stability of an <span class="hlt">Al</span>GaAs photocathode after (Cs, O) activation is always better than that of a GaAs photocathode. After multiple recaesiations, the photocurrent decay curves of the <span class="hlt">Al</span>GaAs photocathode are nearly coincident, which means a nearly constant operational lifetime. Moreover, operational lifetime of an <span class="hlt">Al</span>GaAs photocathode is longer than that of a GaAs photocathode, which further illuminates that <span class="hlt">Al</span>GaAs photocathodes are superior to GaAs photocathodes in stability and repeatability under markedly harsher vacuum conditions.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.osti.gov/scitech/servlets/purl/647049','SCIGOV-STC'); return false;" href="http://www.osti.gov/scitech/servlets/purl/647049"><span>Effect of the Keck telescope`s segmented <span class="hlt">primary</span> on the performance on the Keck adaptive optics <span class="hlt">system</span></span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Gavel, D.</p> <p>1997-06-01</p> <p>The 349 degree of freedom Keck adaptive optics <span class="hlt">system</span> will be mapped on to the 36 segment Keck <span class="hlt">primary</span> mirror. Each telescope segment is independently controlled in piston and tilt by an active control <span class="hlt">system</span> and each segment also has its own set of aberrations. This presents a unique set of problems for the Keck adaptive optics <span class="hlt">system</span>, not encountered with continuous <span class="hlt">primaries</span>. To a certain extent the low order segment aberrations, beginning with focus, can be corrected statically by the adaptive optic <span class="hlt">system</span>. However, the discontinuous surface at the segment edges present special problems in sensing and correcting wavefront with laser guide stars or natural guide stars.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017JEMat.tmp...19A','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017JEMat.tmp...19A"><span>Effects of Codoping with Ga and P on Thermoelectric Properties of Ba8<span class="hlt">Al</span>16Si30 Clathrate <span class="hlt">System</span></span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Anno, Hiroaki; Ueda, Takahiro; Okamoto, Kazuya</p> <p>2017-01-01</p> <p>We have investigated the effects of Codoping With Ga and P on the thermoelectric properties of the Ba8<span class="hlt">Al</span>16Si30 clathrate <span class="hlt">system</span>, attempting to optimize the carrier concentration. The elastic properties, which are important for design of thermoelectric devices, were investigated by ultrasonic testing. Ga/P-codoped specimens with nominal compositions Ba8<span class="hlt">Al</span>16Ga x Si30-2x P x (x = 1.0, 1.5, 2.0) were prepared by arc melting and spark plasma sintering and their Seebeck coefficient, electrical conductivity, and thermal conductivity were measured. Analytical studies revealed that the total content of <span class="hlt">Al</span> and Ga, expressed as atoms per formula unit, increased to 15.65 at nominal x = 2.0, exceeding the maximum content (y = 15.16) of <span class="hlt">Al</span> for the Ba8<span class="hlt">Al</span> y Si46-y clathrate <span class="hlt">system</span>. Ultrasonic tests determined the Young's modulus, shear modulus, bulk modulus, and Poisson's ratio to be 102.55 GPa, 40.14 GPa, 76.85 GPa, and 0.2775, respectively, for Ba8<span class="hlt">Al</span>16Ga x Si30-2x P x (x = 2.0). The Hall carrier concentration decreased from ˜1.0 × 1021 cm-3 for Ba8<span class="hlt">Al</span> y Si46-y to ˜6.3 × 1020 cm-3 for Ba8<span class="hlt">Al</span>16Ga x Si30-2x P x (x = 2.0), suggesting that Ga/P codoping may be useful for tuning the carrier concentration. The value of the Seebeck coefficient at ˜320 K increased from -46 μV K-1 for Ba8<span class="hlt">Al</span> y Si46-y to -67 μV K-1 for Ba8<span class="hlt">Al</span>16Ga x Si30-2x P x (x = 2.0). The dimensionless thermoelectric figure␣of merit ZT at 900 K improved from ˜0.4 for Ba8<span class="hlt">Al</span> y Si46-y to ˜0.47 for Ba8<span class="hlt">Al</span>16Ga x Si30-2x P x (x = 2.0).</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_15");'>15</a></li> <li><a href="#" onclick='return showDiv("page_16");'>16</a></li> <li class="active"><span>17</span></li> <li><a href="#" onclick='return showDiv("page_18");'>18</a></li> <li><a href="#" onclick='return showDiv("page_19");'>19</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_17 --> <div id="page_18" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_16");'>16</a></li> <li><a href="#" onclick='return showDiv("page_17");'>17</a></li> <li class="active"><span>18</span></li> <li><a href="#" onclick='return showDiv("page_19");'>19</a></li> <li><a href="#" onclick='return showDiv("page_20");'>20</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="341"> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017JEMat..46.1730A','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017JEMat..46.1730A"><span>Effects of Codoping with Ga and P on Thermoelectric Properties of Ba8<span class="hlt">Al</span>16Si30 Clathrate <span class="hlt">System</span></span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Anno, Hiroaki; Ueda, Takahiro; Okamoto, Kazuya</p> <p>2017-03-01</p> <p>We have investigated the effects of Codoping With Ga and P on the thermoelectric properties of the Ba8<span class="hlt">Al</span>16Si30 clathrate <span class="hlt">system</span>, attempting to optimize the carrier concentration. The elastic properties, which are important for design of thermoelectric devices, were investigated by ultrasonic testing. Ga/P-codoped specimens with nominal compositions Ba8<span class="hlt">Al</span>16Ga x Si30-2 x P x ( x = 1.0, 1.5, 2.0) were prepared by arc melting and spark plasma sintering and their Seebeck coefficient, electrical conductivity, and thermal conductivity were measured. Analytical studies revealed that the total content of <span class="hlt">Al</span> and Ga, expressed as atoms per formula unit, increased to 15.65 at nominal x = 2.0, exceeding the maximum content ( y = 15.16) of <span class="hlt">Al</span> for the Ba8<span class="hlt">Al</span> y Si46- y clathrate <span class="hlt">system</span>. Ultrasonic tests determined the Young's modulus, shear modulus, bulk modulus, and Poisson's ratio to be 102.55 GPa, 40.14 GPa, 76.85 GPa, and 0.2775, respectively, for Ba8<span class="hlt">Al</span>16Ga x Si30-2 x P x ( x = 2.0). The Hall carrier concentration decreased from ˜1.0 × 1021 cm-3 for Ba8<span class="hlt">Al</span> y Si46- y to ˜6.3 × 1020 cm-3 for Ba8<span class="hlt">Al</span>16Ga x Si30-2 x P x ( x = 2.0), suggesting that Ga/P codoping may be useful for tuning the carrier concentration. The value of the Seebeck coefficient at ˜320 K increased from -46 μV K-1 for Ba8<span class="hlt">Al</span> y Si46- y to -67 μV K-1 for Ba8<span class="hlt">Al</span>16Ga x Si30-2 x P x ( x = 2.0). The dimensionless thermoelectric figure of merit ZT at 900 K improved from ˜0.4 for Ba8<span class="hlt">Al</span> y Si46- y to ˜0.47 for Ba8<span class="hlt">Al</span>16Ga x Si30-2 x P x ( x = 2.0).</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/24800324','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/24800324"><span>District nurses' experiences with the free-choice <span class="hlt">system</span> in Swedish <span class="hlt">primary</span> care.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Hollman, Djana; Lennartsson, Sandra; Rosengren, Kristina</p> <p>2014-01-01</p> <p>This article aims to describe the experiences of district nurses regarding their work situation after the free-choice <span class="hlt">system</span> in <span class="hlt">primary</span> care in Sweden was implemented. The study comprised a total of 17 semi-structured narratives with district nurses. The narratives were analysed using manifest qualitative content analysis. One category,'being an underused resource', and three subcategories, 'being financially aware','being flexible' and 'being appealing', were identified. A focus on economic benefit can limit the cooperation and exchange of experiences within and between different care units, which could have a negative impact on the quality of care due to competition between different care providers. Underused resources and restrictions in terms of improvement skills have an impact on job satisfaction and the working environment, and affect the quality of care as a result.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/22002486','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/22002486"><span><span class="hlt">Primary</span> central nervous <span class="hlt">system</span> lymphoma: implication of high-dose chemotherapy followed by auto-SCT.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Reddy, N; Savani, B N</p> <p>2012-10-01</p> <p><span class="hlt">Primary</span> central nervous <span class="hlt">system</span> lymphoma is a rare and distinct subtype of non-Hodgkin's lymphoma that is sensitive to radiation and chemotherapy. Decisions regarding the initial therapeutic approach are influenced by age and risk of therapy-related neurotoxicity. Despite several albeit small phase II studies, and the acknowledged need for larger prospective trials, there is supporting evidence to consider auto-SCT following induction chemotherapy in patients with good performance status. The international extranodal lymphoma study group is conducting a randomized phase II study comparing consolidative radiation therapy to high-dose therapy. Novel therapeutic options including early aggressive approach with upfront auto-SCT and strategies to prevent relapse following transplantation is an area of focus.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3458413','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3458413"><span>Salvage Therapy for Refractory Aids-Related <span class="hlt">Primary</span> Central Nervous <span class="hlt">System</span> Lymphoma</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Ferro, Hugo; Parino, Eduardo</p> <p>2012-01-01</p> <p>A 27-year-old male patient presented with speech disorders and multiple brain masses on MRI evaluation. He tested positive for HIV. A sterotactic biopsy diagnosed <span class="hlt">primary</span> central nervous <span class="hlt">system</span> lymphoma (diffuse large B-cell lymphoma). After two cycles of high-dose metotrexate (HD-MTX-)-based chemotherapy, the tumor progressed. He underwent whole brain radiotherapy achieving complete response. Six cycles of consolidating immunochemotherapy with rituximab-temozolomide were administered after radiation. Forty-three months after remission, he has not recurred and his neurological status is optimal. Younger HIV patients with refractory PCNSL and preserved immune function can face salvage therapy successfully achieving long term remissions with no remarkable neurotoxicity. PMID:23029628</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/23029628','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/23029628"><span>Salvage therapy for refractory AIDS-related <span class="hlt">primary</span> central nervous <span class="hlt">system</span> lymphoma.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Ferro, Hugo; Parino, Eduardo</p> <p>2012-01-01</p> <p>A 27-year-old male patient presented with speech disorders and multiple brain masses on MRI evaluation. He tested positive for HIV. A sterotactic biopsy diagnosed <span class="hlt">primary</span> central nervous <span class="hlt">system</span> lymphoma (diffuse large B-cell lymphoma). After two cycles of high-dose metotrexate (HD-MTX-)-based chemotherapy, the tumor progressed. He underwent whole brain radiotherapy achieving complete response. Six cycles of consolidating immunochemotherapy with rituximab-temozolomide were administered after radiation. Forty-three months after remission, he has not recurred and his neurological status is optimal. Younger HIV patients with refractory PCNSL and preserved immune function can face salvage therapy successfully achieving long term remissions with no remarkable neurotoxicity.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/22576396','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/22576396"><span>A case of <span class="hlt">primary</span> central nervous <span class="hlt">system</span> lymphoma presenting diffuse infiltrative leukoencephalopathy.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Yamamoto, Tatsuya; Kojima, Kazuho; Koibuchi, Katsura; Ito, Shoichi; Higuchi, Yoshinori; Iwadate, Yasuo; Oide, Takashi; Kuwabara, Satoshi</p> <p>2012-01-01</p> <p>A 58-year-old immunocompetent man gradually developed loss of appetite, cognitive decline, gait disturbances, and personality changes over 4 months. Brain magnetic resonance imaging (MRI) revealed bilateral diffuse leukoencephalopathy without mass formation on admission. His condition progressively deteriorated, and we treated him with intravenous high-dose steroids. His symptoms improved rapidly, but exacerbated when therapy was withdrawn. A brain biopsy was performed, and the diagnosis of <span class="hlt">primary</span> central nervous <span class="hlt">system</span> lymphoma (PCNSL) was confirmed. He was successfully treated with high-dose methotrexate therapy. Although it is difficult to diagnose PCNSL without mass formation in the early stages, steroid responsiveness is important and brain biopsy is essential for the correct diagnosis of PCNSL.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/23904430','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/23904430"><span>Post-traumatic basal ganglia haemorrhage in a child with <span class="hlt">primary</span> central nervous <span class="hlt">system</span> lymphoma.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Jankowski, Pawel P; Levy, Michael L; Crawford, John Ross</p> <p>2013-07-31</p> <p><span class="hlt">Primary</span> central nervous <span class="hlt">system</span> lymphoma (PCNSL) is a rare tumour of childhood with 15-20 cases reported yearly in North America. We present a case of a 13-year-old boy diagnosed with PCNSL who presented more than one-and-a-half years post-treatment with high dose cytosine arabinoside and methotrexate with a right-sided basal ganglia haemorrhage on MRI following a concussion while playing organised football against medical advice. There was no evidence of an underlying vascular malformation or recurrent disease by MRI, cerebrospinal fluid analysis or positron emission tomography computed tomography (PET-CT). However, 6 months post-injury he presented with asymptomatic disease recurrence of the frontal lobe. Our case reports an unusual MRI pattern of post-traumatic injury in a child previously treated for PCNSL that would support a recommendation for the avoidance of contact sports in this population.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4943038','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4943038"><span>The <span class="hlt">Systemic</span> Changes to Improve Efficiency in Polish <span class="hlt">Primary</span> Health Care</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Holecki, Tomasz; Romaniuk, Piotr; Woźniak-Holecka, Joanna</p> <p>2016-01-01</p> <p><span class="hlt">Primary</span> health care is an important part of any health care <span class="hlt">system</span>. In highly developed countries it secures the population's most elementary health needs, with particular emphasis on preventive care and early intervention. Polish PHC model is currently undergoing a thorough transformation, associated with the need to adapt to standards designated based on the WHO's criteria, and with reference to the experience of other European countries. The paper describes the process of changes being carried out, in the context of previous experiences of reform relating to the sphere of organization, processes and efficiency. A review and systematization has been made, with regard to the undertaken activities in the field of deregulation and change of legal provisions, which are aimed at achieving the improvement of the efficiency of treatment and resource allocation. A set of recommendations based on expert's discourse have also been provided, with respect to future directions of Polish PHC transformation. PMID:27468269</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4777729','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4777729"><span>Astrocytes As the Main Players in <span class="hlt">Primary</span> Degenerative Disorders of the Human Central Nervous <span class="hlt">System</span></span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Capani, Francisco; Quarracino, Cecilia; Caccuri, Roberto; Sica, Roberto E. P.</p> <p>2016-01-01</p> <p>Along the last years it has been demonstrated that non-neural cells play a major role in the pathogenesis of the <span class="hlt">primary</span> degenerative disorders (PDDs) of the human central nervous <span class="hlt">system</span>. Among them, astrocytes coordinate and participate in many different and complex metabolic processes, in close interaction with neurons. Moreover, increasing experimental evidence hints an early astrocytic dysfunction in these diseases. In this mini review we summarize the astrocytic behavior in PDDs, with special consideration to the experimental observations where astrocytic pathology precedes the development of neuronal dysfunction. We also suggest a different approach that could be consider in human investigations in Alzheimer’s and Parkinson’s disease. We believe that the study of PDDs with human brain samples may hold the key of a paradigmatic physiopathological process in which astrocytes might be the main players. PMID:26973519</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26973519','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26973519"><span>Astrocytes As the Main Players in <span class="hlt">Primary</span> Degenerative Disorders of the Human Central Nervous <span class="hlt">System</span>.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Capani, Francisco; Quarracino, Cecilia; Caccuri, Roberto; Sica, Roberto E P</p> <p>2016-01-01</p> <p>Along the last years it has been demonstrated that non-neural cells play a major role in the pathogenesis of the <span class="hlt">primary</span> degenerative disorders (PDDs) of the human central nervous <span class="hlt">system</span>. Among them, astrocytes coordinate and participate in many different and complex metabolic processes, in close interaction with neurons. Moreover, increasing experimental evidence hints an early astrocytic dysfunction in these diseases. In this mini review we summarize the astrocytic behavior in PDDs, with special consideration to the experimental observations where astrocytic pathology precedes the development of neuronal dysfunction. We also suggest a different approach that could be consider in human investigations in Alzheimer's and Parkinson's disease. We believe that the study of PDDs with human brain samples may hold the key of a paradigmatic physiopathological process in which astrocytes might be the main players.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4999605','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4999605"><span>A <span class="hlt">Systems</span> Model for Ursodeoxycholic Acid Metabolism in Healthy and Patients With <span class="hlt">Primary</span> Biliary Cirrhosis</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Dobbins, RL; O'Connor‐Semmes, RL; Young, MA</p> <p>2016-01-01</p> <p>A <span class="hlt">systems</span> model was developed to describe the metabolism and disposition of ursodeoxycholic acid (UDCA) and its conjugates in healthy subjects based on pharmacokinetic (PK) data from published studies in order to study the distribution of oral UDCA and potential interactions influencing therapeutic effects upon interruption of its enterohepatic recirculation. The base model was empirically adapted to patients with <span class="hlt">primary</span> biliary cirrhosis (PBC) based on current understanding of disease pathophysiology and clinical measurements. Simulations were performed for patients with PBC under two competing hypotheses: one for inhibition of ileal absorption of both UDCA and conjugates and the other only of conjugates. The simulations predicted distinctly different bile acid distribution patterns in plasma and bile. The UDCA model adapted to patients with PBC provides a platform to investigate a complex therapeutic drug interaction among UDCA, UDCA conjugates, and inhibition of ileal bile acid transport in this rare disease population. PMID:27537780</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2010IEITI..91..796S','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2010IEITI..91..796S"><span>Dynamic Scheduling Real-Time Task Using <span class="hlt">Primary</span>-Backup Overloading Strategy for Multiprocessor <span class="hlt">Systems</span></span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Sun, Wei; Yu, Chen; Défago, Xavier; Inoguchi, Yasushi</p> <p></p> <p>The scheduling of real-time tasks with fault-tolerant requirements has been an important problem in multiprocessor <span class="hlt">systems</span>. The <span class="hlt">primary</span>-backup (PB) approach is often used as a fault-tolerant technique to guarantee the deadlines of tasks despite the presence of faults. In this paper we propose a dynamic PB-based task scheduling approach, wherein an allocation parameter is used to search the available time slots for a newly arriving task, and the previously scheduled tasks can be re-scheduled when there is no available time slot for the newly arriving task. In order to improve the schedulability we also propose an overloading strategy for PB-overloading and Backup-backup (BB) overloading. Our proposed task scheduling algorithm is compared with some existing scheduling algorithms in the literature through simulation studies. The results have shown that the task rejection ratio of our real-time task scheduling algorithm is almost 50% lower than the compared algorithms.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/18425300','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/18425300"><span><span class="hlt">Systems</span> for the management of respiratory disease in <span class="hlt">primary</span> care - an international series: Canada.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Kaplan, Alan</p> <p>2008-06-01</p> <p>Canada has a universal health care <span class="hlt">system</span> funded by the government. All people are supposed to have unrestricted access to all essential health care in a timely fashion. Canada has ten provinces and three territories. Health care is funded by each province/territory, with federal payments providing some of the funding. The bulk of the provision of respiratory care in Canada is provided by <span class="hlt">primary</span> care practitioners. Across the country we have a family physician shortage; thus, in many areas of the country there is insufficient access since patients do not actually have a family physician. This has less effect on acute medical services, which can be available in ER or walk-in settings, but certainly does affect the provision of services for chronic illnesses. While thus far the health care <span class="hlt">system</span> is 'free', there are some significant limitations; the commonest is waiting times for specialist care and investigations. Other significant deficiencies include the lack of coverage for medications for both acute and chronic conditions and of medical devices. <span class="hlt">Primary</span> care reforms by local governments have attempted to fix these issues by changing care models. Fee-for-service medicine by physicians is slowly being changed in places to capitation models and other <span class="hlt">systems</span> such as rewards for managing chronic conditions optimally. Ontario has instituted 'reward <span class="hlt">systems</span>' for diabetes and smoking cessation. British Columbia has rewards for multiple chronic diseases. In many areas, care in the provinces is regionalised to allow local arrangements to help decide on where and how care is organised. Respiratory diseases (excluding lung cancer) rank fourth in Canada in the total proportion of direct health care costs (behind neuropsychiatric, injury and cardiovascular diseases). A number of studies have shown that respiratory conditions such as asthma and COPD are underdiagnosed and/or undermanaged. Other conditions need treatment by specialists or physicians with a special interest</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/18537651','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/18537651"><span>Treatment of central nervous <span class="hlt">system</span> involvement associated with <span class="hlt">primary</span> Sjögren's syndrome.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Ozgocmen, Salih; Gur, Ali</p> <p>2008-01-01</p> <p>Sjögren's syndrome (SS) is a chronic autoimmune disease that mainly affects the exocrine glands and usually presents with sicca symptoms of the main mucosal surfaces. The prevalence and the type of central nervous <span class="hlt">system</span> (CNS) tissue damage caused by SS are debatable. The wide spectrum of CNS manifestations, different classification criteria used and unclear inclusion or exclusion criteria pose some difficulty reviewing these studies. Careful examination of the SS patients and to be aware of neurological findings which may be associated with suspicious CNS involvement is highly important. Central nervous <span class="hlt">system</span> may also hypothetically have a role in the pathophysiology of SS. The wide spectrum of CNS involvement includes focal (sensorial and motor deficits, brain stem, cerebellar lesions, seizure, migraine etc.) or non-focal (encephalomyelitis, aseptic meningitis, neuropsychiatric dysfunctions), spinal cord (myelopathy, transverse myelitis, motor neuron disease etc.) findings or multiple sclerosis-like illness and optic neuritis. Evolving imaging techniques such as single photon emission computed tomography (SPECT), magnetic resonance spectroscopy or magnetization transfer imaging are promising for better understanding the nature of CNS involvement in SS. Treatments usually comprise symptomatic approach in milder cases however, pulse cyclophosphamide and steroids or other immunosuppressants (chlorambucil or azathioprine) are required in cases with progressive symptoms leading to neurological impairment. Anti-TNF agents (infliximab and etanercept) and B cell targeted therapies (rituximab and epratuzumab) are used in <span class="hlt">primary</span> SS however their efficacy on CNS manifestation is still unclear. Randomized, multicenter studies are warranted to confirm the efficacy of treatment regimes which were reported to be effective in anecdotal reports or in small uncontrolled series. This article reviews the clinical approach to current therapy of CNS involvement in patients with</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015DPS....4740209B','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015DPS....4740209B"><span>Geodynamic stability of the <span class="hlt">primary</span> in the binary asteroid <span class="hlt">system</span> 65803 Didymos</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Barnouin, Olivier S.; Maurel, Clara; Richardson, Derek C.; Ballouz, Ronald-Louis; Schwartz, Stephen; Michel, Patrick</p> <p>2015-11-01</p> <p>The moon of the near-Earth binary asteroid 65803 Didymos is the target of the Asteroid Impact and Deflection Assessment (AIDA) mission. This mission is a joint concept between NASA and ESA to investigate the effectiveness of a kinetic impactor in deflecting an asteroid. The mission is composed of two components: the NASA-led Double Asteroid Redirect Test (DART) that will impact the Didymos moon, and the ESA-led Asteroid Impact Monitoring (AIM) mission that will characterize the Didymos <span class="hlt">system</span>. In order to provide AIDA constraints on the physical character of the both objects in this binary <span class="hlt">system</span>, we undertook preliminary numerical investigations to evaluate the stability of the shape of the <span class="hlt">primary</span> using its rapid 2.26 h rotation. We modeled the <span class="hlt">primary</span> as a rubble pile. Each model consisted of thousands of uniform rigid spheres collapsed together under their own gravity to form a spherical pile that was then carved to match the current radar-derived shape model of the <span class="hlt">primary</span>, as well as other comparable shapes (e.g. asteroid 1999 KW4, spheres) that were scaled to match best estimates of the size of Didymos. Each model was given a starting rotation period of 6 h with the spin axis aligned to the pole. At each timestep the spin rate was increased by a small amount so that after about 1 million timesteps the spin would match the observed rotation of 2.26 h. We tested a range of bulk densities spanning the current observational uncertainty (mean 2.4 g/cc) using "gravel"-like material parameters that provide significant resistance to sliding and rolling. We find that at the upper range of the density uncertainty it is possible for Didymos to hold its shape and not lose mass at its nominal rotation period, without the need for cohesive forces. At lower densities or with smoother particles, significant shape change occurs and mass loss is possible. We conclude that based on the radar shape available at the time of this writing, Didymos is marginally stable as a rubble</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27441147','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27441147"><span>Thermodynamic simulation on mineralogical composition of CaO-SiO2-<span class="hlt">Al</span>2O3-MgO quaternary slag <span class="hlt">system</span>.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Liu, Chao; Zhang, Yu-Zhu; Li, Jie; Li, Jun-Guo; Kang, Yue</p> <p>2016-01-01</p> <p>It is necessary to elucidate the crystallization thermodynamic of mineralogical phases during the cooling process of the molten BFS with different chemical composition, because the high-melting point mineral phase maybe crystallized during the fiber forming and thereafter cooling process. Thermodynamic calculation software FactSage6.4 and the hot remelting experiments were performed to explore the influence of basicity, <span class="hlt">Al</span>2O3 content and MgO content on the crystallization of mineralogical components and their transformation. The results showed that the main mineralography of the CaO-SiO2-<span class="hlt">Al</span>2O3-MgO quaternary slag <span class="hlt">system</span> was melilite, and a certain amount of anorthite and calcium metasilicate. The crystallographic temperature of melilite is increased with the increasing of basicity, MgO and <span class="hlt">Al</span>2O3 content, which has a significant impact on the utilization performance of the mineral wool prepared with the hot blast furnace slag directly. With the increasing of basicity, there was a tendency that crystallographic amount of melilite increased to the summit and then declined, while the amount of anorthite and calcium metasilicate decreased consistently. Finally, these two mineralogical components could be replaced by magnesium rhodonite and spinel with the increasing of basicity. When the basicity and MgO content were 1.0 and 9 %, the crystallographic mass ratio of melilite and anorthite increased, while that of calcium silicate declined, and replaced by spinel finally with the increasing of <span class="hlt">Al</span>2O3 content. When the basicity and <span class="hlt">Al</span>2O3 content were 1.0 and 13 %, the crystallographic mass ratio of melilite increased, while that of anorthite and calcium silicate declined, and replaced by pyroxene and spinel with the increasing of MgO content. To decline fiberization temperature of the melt BFS, the basicity, MgO and <span class="hlt">Al</span>2O3 content should be decreased during the modification process of chemical composition, because the crystallization temperature of the <span class="hlt">primary</span> crystalline</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/1997JSSCh.131...24T','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/1997JSSCh.131...24T"><span>An XRD and Electron Diffraction Study of Cristobalite-Related Phases in the Na<span class="hlt">Al</span>O 2-Na<span class="hlt">Al</span>SiO 4<span class="hlt">System</span></span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Thompson, John G.; Melnitchenko, Alexandra; Palethorpe, Stephen R.; Withers, Ray L.</p> <p>1997-06-01</p> <p>A detailed study of the sodium aluminate-carnegieite <span class="hlt">system</span> (Na2-x<span class="hlt">Al</span>2-xSixO4, 0≤x≤1) at temperatures between 800 and 1300°C has revealed five previously unreported phases. All of the new phases can be described as modulated variants of an underlyingβ-cristobalite parent structure. Atx≈0.05 theγ-Na<span class="hlt">Al</span>O2-type structure (P41212,a=1/2ap,c=cp) (p=parent) is stabilized to room-temperature; atx≈0.2-0.45 an orthorhombic (Pbca,a=2ap,b=2bp,c=1/2cp) KGaO2-type structure is obtained, except atx≈0.35 where a new tetragonal (P41212,a=2ap,c=cp) phase is observed; atx≈0.5-0.6 a new cubic (P213,a=2ap) phase is obtained; atx≈0.7-0.9 a new orthorhombic (Pc21b,a=2ap,b=2bp,c=2cp) phase is obtained. XRD and electron diffraction data, refined unit cell dimensions, and the phase relationships at 1300°C are presented. The proposed space group symmetries are based on observed extinction conditions and constraints provided by a modulated structure description of the new phases. The materials are prepared by gel synthesis followed by solid state reaction in air.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/1570066','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/1570066"><span>[A case of <span class="hlt">primary</span> intracerebral malignant lymphoma in <span class="hlt">systemic</span> lupus erythematosus].</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Tomabechi, M; Daita, G; Ohgami, S; Yonemasu, Y; Maekawa, I</p> <p>1992-04-01</p> <p>The patient, a 44-year-old female, was admitted to our department because of right hemiparesis and left oculomotor nerve palsy on February 7, 1986. Neither lymphadenopathy nor hepatosplenomegaly was present. She had been treated with prednisolone for <span class="hlt">systemic</span> lupus erythematosus (SLE) for one and a half year before admission. The CT scan revealed a homogeneously enhanced mass lesion from the midbrain through the thalamus on the right side. The whole body gallium scintigram showed no abnormal uptake except in the brain. Stereotaxic biopsy was performed. Histopathological diagnosis was malignant lymphoma, diffuse, large cell type (International Working Formulation). The enhanced mass lesion disappeared after radiation therapy. Subsequently, she received chemotherapy. She remained well until May 1988 when she died because of the <span class="hlt">systemic</span> lymphadenopathy. The association of malignant lymphoma and SLE has appeared occasionally in the literature. <span class="hlt">Primary</span> intracerebral malignant lymphoma associated with SLE is much rarer but it should be considered in the differential diagnosis of symptoms of the central nervous <span class="hlt">system</span> in a patient with SLE. Therefore, biopsy of a cerebral mass lesion is mandatory if appropriate therapy such as radiation and chemotherapy is to be administered.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/10563430','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/10563430"><span>Radiotherapy in the treatment of <span class="hlt">primary</span> central nervous <span class="hlt">system</span> lymphoma (PCNSL).</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Nelson, D F</p> <p>1999-07-01</p> <p>The use of radiotherapy alone to treat <span class="hlt">primary</span> central nervous <span class="hlt">system</span> lymphoma (PCNSL) does not produce the high local control and survival rates that it does in limited extranodal non-Hodgkin's lymphoma outside the central nervous <span class="hlt">system</span> (CNS). Even with doses of whole brain radiation therapy (WBRT) to 40+20 Gy boost, the Radiation Therapy Oncology Group (RTOG) reported a local control rate of 39%. Seventy-nine percent of recurrences were in the 60 Gy region. The median survival was 11.6 months. This response to local radiotherapy is quite different from the response of non-CNS Diffuse Large Cell Lymphoma where doses of 30-40 and >40 Gy have a 75-90% local control rate. Neither <span class="hlt">systemic</span> lymphoma nor PCNSL have a classic radiotherapy dose response. For PCNSL there appears to be a threshold dose that ranges in the literature between 30 and > 50 Gy with a median of 40 Gy. Therefore, when radiotherapy is combined with chemotherapy that crosses the BBB, WBRT and/or boost doses may be able to be decreased, especially in patients achieving a complete response. Promising data from the Centre Leon Berard suggest that this is possible. When such chemotherapy was combined with intrathecal chemotherapy and 20 Gy WBRT, they obtained a 56% actuarial 5 year survival rate. Confirmation of single institution reports of favorable results such as these are needed. Cooperative group and intergroup trials are needed to define optimal therapy.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26307856','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26307856"><span>Changes in functional connectivity of pain modulatory <span class="hlt">systems</span> in women with <span class="hlt">primary</span> dysmenorrhea.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Wei, Shyh-Yuh; Chao, Hsiang-Tai; Tu, Cheng-Hao; Li, Wei-Chi; Low, Intan; Chuang, Chih-Ying; Chen, Li-Fen; Hsieh, Jen-Chuen</p> <p>2016-01-01</p> <p>Menstrual pain is the most prevalent gynecological complaint, and is usually without organic cause (termed <span class="hlt">primary</span> dysmenorrhea, PDM). The high comorbidity in the later life of PDM with many functional pain disorders (associated with central dysfunction of pain inhibition, eg, fibromyalgia) suggests possible maladaptive functionality of pain modulatory <span class="hlt">systems</span> already occurred in young PDM women, making them vulnerable to functional pain disorders. Periaqueductal gray (PAG) matter functions as a critical hub in the neuraxis of pain modulatory <span class="hlt">systems</span>; therefore, we investigated the functional connectivity of PAG in PDM. Forty-six PDM subjects and 49 controls received resting-state functional magnetic resonance imaging during menstruation and periovulatory phases. The PAG of PDM subjects exhibited adaptive/reactive hyperconnectivity with the sensorimotor cortex during painful menstruation, whereas it exhibited maladaptive hypoconnectivity with the dorsolateral prefrontal cortex and default mode network (involving the ventromedial prefrontal cortex, posterior cingulate cortex, or posterior parietal cortex) during menstruation or periovulatory phase. We propose that the maladaptive descending pain modulatory <span class="hlt">systems</span> in PDM may underpin the central susceptibility to subsequent development of various functional disorders later in life. This hypothesis is corroborated by the growing body of evidence that hypoconnectivity between PAG and default mode network is a coterminal to many functional pain disorders.</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_16");'>16</a></li> <li><a href="#" onclick='return showDiv("page_17");'>17</a></li> <li class="active"><span>18</span></li> <li><a href="#" onclick='return showDiv("page_19");'>19</a></li> <li><a href="#" onclick='return showDiv("page_20");'>20</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_18 --> <div id="page_19" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_17");'>17</a></li> <li><a href="#" onclick='return showDiv("page_18");'>18</a></li> <li class="active"><span>19</span></li> <li><a href="#" onclick='return showDiv("page_20");'>20</a></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="361"> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/scitech/biblio/1000894','SCIGOV-STC'); return false;" href="https://www.osti.gov/scitech/biblio/1000894"><span>Modeling and Analysis of Alternative Concept of ITER Vacuum Vessel <span class="hlt">Primary</span> Heat Transfer <span class="hlt">System</span></span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Carbajo, Juan J; Yoder Jr, Graydon L; Dell'Orco, Giovanni; Curd, Warren; Kim, Seokho H</p> <p>2010-01-01</p> <p>A RELAP5-3D model of the ITER (Latin for the way ) vacuum vessel (VV) <span class="hlt">primary</span> heat transfer <span class="hlt">system</span> has been developed to evaluate a proposed design change that relocates the heat exchangers (HXs) from the exterior of the tokamak building to the interior. This alternative design protects the HXs from external hazards such as wind, tornado, and aircraft crash. The proposed design integrates the VV HXs into a VV pressure suppression <span class="hlt">system</span> (VVPSS) tank that contains water to condense vapour in case of a leak into the plasma chamber. The proposal is to also use this water as the ultimate sink when removing decay heat from the VV <span class="hlt">system</span>. The RELAP5-3D model has been run under normal operating and abnormal (decay heat) conditions. Results indicate that this alternative design is feasible, with no effects on the VVPSS tank under normal operation and with tank temperature and pressure increasing under decay heat conditions resulting in a requirement to remove steam generated if the VVPSS tank low pressure must be maintained.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4926712','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4926712"><span>Patients’ perceptions of the triage <span class="hlt">system</span> in a <span class="hlt">primary</span> healthcare facility, Cape Town, South Africa</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Adeniji, Adeloye Amoo</p> <p>2016-01-01</p> <p>Background In public healthcare facilities, where the patient numbers and the available resources are often disproportionate, triage is used to prioritise when patients are seen. Patients may not understand the triage process and have strong views on how to improve their experience. Aim This study explored the views of patients who had undergone triage in the emergency centre of a <span class="hlt">primary</span> care facility. Setting Gugulethu Community Health Centre, Cape Town. Methods A purposive sample consisted of five women (one coded green, three orange, one yellow) and four men (one coded green and three yellow). A semi-structured qualitative interview was conducted in either Xhosa or English and the transcripts analysed using the framework method. Results All of the respondents complained of a lack of information and poor understanding of the triage process. Those coded green experienced the process as biased and unfair and reported that the triage nurse was rude and unprofessional. By contrast, those coded yellow or orange found the triage nurse to be helpful and professional. Most patients turned to support staff (e.g. security staff or cleaners) for assistance in dealing with the triage <span class="hlt">system</span>. Most patients waited longer than the guidelines recommend and the green-coded patients complained about this issue. Conclusion Patients did not have a good experience of the triage <span class="hlt">system</span>. Managers of the triage <span class="hlt">system</span> need to design better strategies to improve patient acceptance and share information. The important role of support staff needs to be recognised and strengthened. PMID:27380788</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/24111037','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/24111037"><span>A new control method depending on <span class="hlt">primary</span> phase angle of transcutaneous energy transmission <span class="hlt">system</span> for artificial heart.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Miura, H; Saito, I; Sato, F; Shiraishi, Y; Yambe, T; Matsuki, H</p> <p>2013-01-01</p> <p>A new control method for stabilizing output voltage of the transcutaneous energy transmission <span class="hlt">system</span> for artificial heart is proposed. This method is <span class="hlt">primary</span> side, is outside of the body, which is not depending on a signal transmission <span class="hlt">system</span> from the implanted device. The impedance observed from <span class="hlt">primary</span> side changes from inductive to capacitive and the output voltage decreases drastically when the output current is large and the coupling factor is higher than that of the optimal condition. In this case, the driving frequency should be changed to higher so that the phase angle of the <span class="hlt">primary</span> impedance is zero degree. The preliminary examination showed that this control method can enhance the output voltage limit to twice and the feasibility of the <span class="hlt">primary</span> side control.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016MMTB...47.1093K','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016MMTB...47.1093K"><span>Phase Equilibrium Studies of CaO-SiO2-MgO-<span class="hlt">Al</span>2O3 <span class="hlt">System</span> with Binary Basicity of 1.5 Related to Blast Furnace Slag</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Kou, Mingyin; Wu, Shengli; Ma, Xiaodong; Wang, Laixin; Chen, Mao; Cai, Qingwu; Zhao, Baojun</p> <p>2016-04-01</p> <p>Slags play an important role in blast furnace operation, and their compositions are based on the CaO-SiO2-MgO-<span class="hlt">Al</span>2O3 quaternary <span class="hlt">system</span> in many steel companies. The binary basicity (CaO/SiO2 weight ratio) of blast furnace slags, especially <span class="hlt">primary</span> slag and bosh slag, can be as high as 1.5 or higher. Phase equilibria and liquidus temperatures in the CaO-SiO2-MgO-<span class="hlt">Al</span>2O3 <span class="hlt">system</span> with binary basicity of 1.50 are experimentally determined for temperatures in the range 1723 K to 1823 K (1450 °C to 1550 °C). High temperature equilibration, quenching, and electron probe X-ray microanalysis techniques have been used in the present study. The isotherms are obtained in the <span class="hlt">primary</span> phase fields of Ca2SiO4, melilite, spinel, periclase, and merwinite related to blast furnace slags. Effects of <span class="hlt">Al</span>2O3, MgO, and binary basicity on liquidus temperatures have been discussed. In addition, extensive solid solutions have been measured for different <span class="hlt">primary</span> phases and will be used for development and optimization of the thermodynamic database.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/1986GeCoA..50.1911B','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/1986GeCoA..50.1911B"><span>Equilibrium aluminium hydroxo-oxalate phases during initial clay formation; H +-<span class="hlt">Al</span> 3+-oxalic acid-Na + <span class="hlt">system</span></span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Bilinski, Halka; Horvath, Laszlo; Ingri, Nils; Sjöberg, Staffan</p> <p>1986-09-01</p> <p>The conditions necessary for initial clay formation have been studied in different model <span class="hlt">systems</span> comprising different organic acids besides Si and <span class="hlt">Al</span>. In the present paper the solid phases and the precipitation boundary characterizing the subsystem H +-<span class="hlt">Al</span> 3+-oxalic acid (H 2L) are discussed. pH and tyndallometric measurements were performed in an ionic medium of 0.6 M Na(Cl) at 25 °C. The two phases <span class="hlt">Al</span> 3(OH) 7(C 2O 4) · 3H 2O (phase I) and Na<span class="hlt">Al</span>(OH) 2(C 2O 4) · 3H 2O (phase II) determine the precipitation boundary. The following formation constants for the two phases were deduced: lgβ1 = lg([ <span class="hlt">Al</span>3+] -3[ H2C2O4] -1[ H+] 9 = -21.87 ± 0.08 and lgβ11 = lg([ <span class="hlt">Al</span>3+] -1[ H2C2O4] -1[ H+] 4 = -5.61 ± 0.06. Phase I exists in the range [ <span class="hlt">Al</span>] tot≥ 10 -4.4moldm-3,[ H2C2O4] tot ≥ 10 -4.9moldm-3 and at pH < 6.8, thus being a possible precipitate in oxalic-rich natural waters. The more soluble sodium phase is unlikely to exist in natural waters. The two phases are metastable relative to crystalline gibbsite and may be considered as the first precipitation step in the transition from aqueous <span class="hlt">Al</span> oxalates down to stable <span class="hlt">Al</span> hydroxide. Model calculations illustrating these competing hydrolysis-complexation reactions are discussed in terms of predominance and speciation diagrams. The solid phases have been characterized by X-ray analysis of powders, TGA and IR spectra, and tentative structures are proposed. Phase I seems to be an octahedral layer structure, in which 3/5 of the octahedral sites between two close packed oxygen sheets are occupied by <span class="hlt">Al</span> 3+ and the oxalate ion acts as a bridge ligand between two aluminium atoms. Phase II forms a more open sheet structure and has ion exchange properties. Powder data for a phase crystallized from the studied solution after a year are also presented. This phase, Na 4<span class="hlt">Al</span> 2(OH) 2(C 2O 4) 4 · 10H 2O, supports the results from the equilibrium analysis of recent solution data by SJöBERG and ÖHMAN (1985), who have found the dinuclear</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/scitech/biblio/565405','SCIGOV-STC'); return false;" href="https://www.osti.gov/scitech/biblio/565405"><span>Observation, control, and modal analysis of longitudinal coupled-bunch instabilities in the <span class="hlt">ALS</span> via a digital feedback <span class="hlt">system</span></span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Fox, J.D.; Claus, R.; Hindi, H.; Linscott, I.; Prabhakar, S.; Ross, W.; Teytelman, D.; Drago, A.; Serio, M.; Byrd, J.; Corlett, J.; Stover, G.</p> <p>1997-01-01</p> <p>The operation of a longitudinal multibunch damping <span class="hlt">system</span> using digital signal processing (DSP) techniques is shown via measurements from the Lawrence Berkeley Laboratory (LBL) Advanced Light Source (<span class="hlt">ALS</span>). The feedback <span class="hlt">system</span> (developed for use by PEP-II, <span class="hlt">ALS</span>, and DA{Phi}NE) uses a parallel array of signal processors to implement a bunch-by-bunch feedback <span class="hlt">system</span> for sampling rates up to 500 MHz. The programmable DSP <span class="hlt">system</span> allows feedback control as well as accelerator diagnostics. A diagnostic technique is illustrated which uses the DSP <span class="hlt">system</span> to excite and then damp the beam. The resulting 12-ms time domain transient is Fourier analyzed to provide the simultaneous measurement of growth rates and damping rates of all unstable coupled-bunch beam modes. {copyright} {ital 1997 American Institute of Physics.}</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2013JaJAP..52hJF07D','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2013JaJAP..52hJF07D"><span>Enhanced Capability of Photoelectrochemical CO2 Conversion <span class="hlt">System</span> Using an <span class="hlt">Al</span>GaN/GaN Photoelectrode</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Deguchi, Masahiro; Yotsuhashi, Satoshi; Hashiba, Hiroshi; Yamada, Yuka; Ohkawa, Kazuhiro</p> <p>2013-08-01</p> <p>We report significantly improved photosynthesis <span class="hlt">system</span> based on <span class="hlt">Al</span>GaN/GaN photochemical process. The resultant energy conversion efficiency is 0.13% which is the same level as that of real plants. The capability of this <span class="hlt">system</span> is enhanced by high cathode potential due to the reduction of energy loss while utilizing the piezoelectric effect in the <span class="hlt">Al</span>GaN/GaN heterostructure. The Faradaic efficiency of the CO2 conversion to organic materials is enhanced, accompanied by an increment in photocurrent by modification of the <span class="hlt">Al</span>GaN/GaN photoelectrode structure and electrolytes. Furthermore, reaction products such as C2H4 and C2H5OH are generated by light illumination alone.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.osti.gov/scitech/servlets/purl/877181','SCIGOV-STC'); return false;" href="http://www.osti.gov/scitech/servlets/purl/877181"><span>Enhanced Control of PWR <span class="hlt">Primary</span> Coolant Water Chemistry Using Selective Separation <span class="hlt">Systems</span> for Recovery and Recycle of Enriched Boric Acid</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Ken Czerwinski; Charels Yeamans; Don Olander; Kenneth Raymond; Norman Schroeder; Thomas Robison; Bryan Carlson; Barbara Smit; Pat Robinson</p> <p>2006-02-28</p> <p>The objective of this project is to develop <span class="hlt">systems</span> that will allow for increased nuclear energy production through the use of enriched fuels. The developed <span class="hlt">systems</span> will allow for the efficient and selective recover of selected isotopes that are additives to power water reactors' <span class="hlt">primary</span> coolant chemistry for suppression of corrosion attack on reactor materials.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://hdl.handle.net/2060/19900019290','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/19900019290"><span>Liquid Rocket Booster (LRB) for the Space Transportation <span class="hlt">System</span> (STS) <span class="hlt">systems</span> study. Appendix F: Performance and trajectory for <span class="hlt">ALS</span>/LRB launch vehicles</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p></p> <p>1989-01-01</p> <p>By simply combining two baseline pump-fed LOX/RP-1 Liquid Rocket Boosters (LRBs) with the Denver core, a launch vehicle (Option 1 Advanced Launch <span class="hlt">System</span> (<span class="hlt">ALS</span>)) is obtained that can perform both the 28.5 deg (<span class="hlt">ALS</span>) mission and the polar orbit <span class="hlt">ALS</span> mission. The Option 2 LRB was obtained by finding the optimum LOX/LH2 engine for the STS/LRB reference mission (70.5 K lb payload). Then this engine and booster were used to estimate <span class="hlt">ALS</span> payload for the 28.5 deg inclination <span class="hlt">ALS</span> mission. Previous studies indicated that the optimum number of STS/LRB engines is four. When the engine/booster sizing was performed, each engine had 478 K lb sea level thrust and the booster carried 625,000 lb of useable propellant. Two of these LRBs combined with the Denver core provided a launch vehicle that meets the payload requirements for both the <span class="hlt">ALS</span> and STS reference missions. The Option 3 LRB uses common engines for the cores and boosters. The booster engines do not have the nozzle extension. These engines were sized as common <span class="hlt">ALS</span> engines. An <span class="hlt">ALS</span> launch vehicle that has six core engines and five engines per booster provides 109,100 lb payload for the 28.5 deg mission. Each of these LOX/LH2 LRBs carries 714,100 lb of useable propellant. It is estimated that the STS/LRB reference mission payload would be 75,900 lb.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.osti.gov/scitech/servlets/purl/1221954','SCIGOV-STC'); return false;" href="http://www.osti.gov/scitech/servlets/purl/1221954"><span>Simulation of atomic diffusion in the Fcc Ni<span class="hlt">Al</span> <span class="hlt">system</span>: A kinetic Monte Carlo study</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Alfonso, Dominic R.; Tafen, De Nyago</p> <p>2015-04-28</p> <p>The atomic diffusion in fcc Ni<span class="hlt">Al</span> binary alloys was studied by kinetic Monte Carlo simulation. The environment dependent hopping barriers were computed using a pair interaction model whose parameters were fitted to relevant data derived from electronic structure calculations. Long time diffusivities were calculated and the effect of composition change on the tracer diffusion coefficients was analyzed. These results indicate that this variation has noticeable impact on the atomic diffusivities. A reduction in the mobility of both Ni and <span class="hlt">Al</span> is demonstrated with increasing <span class="hlt">Al</span> content. As a result, examination of the pair interaction between atoms was carried out for the purpose of understanding the predicted trends.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016SPIE.9698E..0VE','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016SPIE.9698E..0VE"><span>Creating an optical spectroscopy <span class="hlt">system</span> for use in a <span class="hlt">primary</span> care clinical setting (Conference Presentation)</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Eshein, Adam; Nguyen, The-Quyen; Radosevich, Andrew J.; Gould, Bradley; Wu, Wenli; Konda, Vani; Yang, Leslie W.; Koons, Ann; Feder, Seth; Valuckaite, Vesta; Roy, Hemant K.; Backman, Vadim</p> <p>2016-03-01</p> <p>While there are a plethora of in-vivo spectroscopic techniques that have demonstrated the ability to detect a number of diseases in research trials, very few techniques have successfully become a fully realized clinical technology. This is primarily due to the stringent demands on a clinical device for widespread implementation. Some of these demands include: simple operation requiring minimal or no training, safe for in-vivo patient use, no disruption to normal clinic workflow, tracking of <span class="hlt">system</span> performance, warning for measurement abnormality, and meeting all FDA guidelines for medical use. Previously, our group developed a fiber optic probe-based optical sensing technique known as low-coherence enhanced backscattering spectroscopy (LEBS) to quantify tissue ultrastructure in-vivo. Now we have developed this technique for the application of prescreening patients for colonoscopy in a <span class="hlt">primary</span> care (PC) clinical setting. To meet the stringent requirements for a viable medical device used in a PC clinical setting, we developed several novel components including an automated calibration tool, optical contact sensor for signal acquisition, and a contamination sensor to identify measurements which have been affected by debris. The end result is a state-of-the-art medical device that can be realistically used by a PC physician to assess a person's risk for harboring colorectal precancerous lesions. The pilot study of this <span class="hlt">system</span> shows great promise with excellent stability and accuracy in identifying high-risk patients. While this <span class="hlt">system</span> has been designed and optimized for our specific application, the <span class="hlt">system</span> and design concepts are universal to most in-vivo fiber optic based spectroscopic techniques.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.osti.gov/scitech/servlets/purl/985287','SCIGOV-STC'); return false;" href="http://www.osti.gov/scitech/servlets/purl/985287"><span>RELAP5 Model of the First Wall/Blanket <span class="hlt">Primary</span> Heat Transfer <span class="hlt">System</span></span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Popov, Emilian L; Yoder Jr, Graydon L; Kim, Seokho H</p> <p>2010-06-01</p> <p>ITER inductive power operation is modeled and simulated using a <span class="hlt">system</span> level computer code to evaluate the behavior of the <span class="hlt">Primary</span> Heat Transfer <span class="hlt">System</span> (PHTS) and predict parameter operational ranges. The control algorithm strategy and derivation are summarized in this report as well. A major feature of ITER is pulsed operation. The plasma does not burn continuously, but the power is pulsed with large periods of zero power between pulses. This feature requires active temperature control to maintain a constant blanket inlet temperature and requires accommodation of coolant thermal expansion during the pulse. In view of the transient nature of the power (plasma) operation state a transient <span class="hlt">system</span> thermal-hydraulics code was selected: RELAP5. The code has a well-documented history for nuclear reactor transient analyses, it has been benchmarked against numerous experiments, and a large user database of commonly accepted modeling practices exists. The process of heat deposition and transfer in the blanket modules is multi-dimensional and cannot be accurately captured by a one-dimensional code such as RELAP5. To resolve this, a separate CFD calculation of blanket thermal power evolution was performed using the 3-D SC/Tetra thermofluid code. A 1D-3D co-simulation more realistically models FW/blanket internal time-dependent thermal inertia while eliminating uncertainties in the time constant assumed in a 1-D <span class="hlt">system</span> code. Blanket water outlet temperature and heat release histories for any given ITER pulse operation scenario are calculated. These results provide the basis for developing time dependent power forcing functions which are used as input in the RELAP5 calculations.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.osti.gov/scitech/servlets/purl/10104836','SCIGOV-STC'); return false;" href="http://www.osti.gov/scitech/servlets/purl/10104836"><span><span class="hlt">Primary</span> standards laboratory report, 1st half 1994</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Not Available</p> <p>1994-11-01</p> <p>Sandia National Laboratories operates the <span class="hlt">Primary</span> Standards Laboratory for the Department of Energy, Albuquerque Operations Office (DOE/<span class="hlt">AL</span>). This report summarizes metrology activities that received emphasis in the first half of 1994 and provides information pertinent to the operation of the DOE/<span class="hlt">AL</span> <span class="hlt">system</span>-wide Standards and Calibration Program.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5321213','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5321213"><span><span class="hlt">Primary</span> Central Nervous <span class="hlt">System</span> Lymphoma: A Critical Review of the Role of Surgery for Resection</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Yun, Jonathan; Iwamoto, Fabio M.; Sonabend, Adam M.</p> <p>2016-01-01</p> <p>Background <span class="hlt">Primary</span> central nervous <span class="hlt">system</span> lymphomas (PCNSL) are rare CNS tumors that carry a poor prognosis, with most patients suffering recurrence. Progress has been made in the treatment of this pathology, notably with the widespread use of <span class="hlt">systemic</span> high dose methotrexate. However, unlike most other malignant CNS neoplasms, surgery for cytoreduction is not routinely performed for this disease, mainly as a result of negative experiences decades ago. Since these studies were published, the availability of intraoperative monitoring, MR imaging and neuro-navigation as well as surgical adjuncts such as fluorescence- guided resection have greatly improved the safety of intracranial procedures. More recent data is suggestive of a potential survival benefit for resection of single PCNSL lesions when patients are subsequently treated with modern regimen high-dose methotrexate, yet this evidence is limited, and should be interpreted conservatively. Methods and findings A systematic review of the literature was performed to identify trials evaluating surgical options for the treatment of PCNSL. Conclusion In this review, we provide a critical overview of the evidence favoring and discouraging resection for PCNSL. This literature suffers from several biases and limitations that must be considered in the context of the extrapolation of this literature into clinical decision-making. PMID:28239600</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/22426596','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/22426596"><span><span class="hlt">Primary</span> central nervous <span class="hlt">system</span> anaplastic large-cell lymphoma mimicking lymphomatosis cerebri.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Sugino, Toshiya; Mikami, Takeshi; Akiyama, Yukinori; Wanibuchi, Masahiko; Hasegawa, Tadashi; Mikuni, Nobuhiro</p> <p>2013-01-01</p> <p><span class="hlt">Primary</span> central nervous <span class="hlt">system</span> lymphoma (PCNSL) is usually diffuse large B-cell lymphoma. Anaplastic large-cell lymphoma (ALCL) rarely occurs in the central nervous <span class="hlt">system</span>. PCNSL always presents as single or multiple nodular contrast-enhancing mass lesions within T2-hyperintense areas on magnetic resonance imaging (MRI). Infrequently, diffuse infiltrating change with little contrast enhancement called lymphomatosis cerebri can be seen in PCNSL. In this report, we describe a 75-year-old immunocompetent man who had progressive dementia. On MRI, diffuse white matter lesions with little contrast enhancement were observed to gradually progress, which was clinically consistent with his worsening condition. A biopsy specimen revealed non-destructive, diffusely infiltrating, anaplastic large CD30-positive lymphoma, indicating a diagnosis of ALCL. After the biopsy, he was treated by whole brain irradiation (total 46 Gy) and focal boost irradiation (total 14 Gy). However, his performance status worsened and there was no symptom improvement. The patient died 8 months after symptom onset. The clinical course, diagnostic workup, pathologic correlates, and treatment outcomes are described herein.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4802180','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4802180"><span>A Conceptual Framework for Evaluation of Public Health and <span class="hlt">Primary</span> Care <span class="hlt">System</span> Performance in Iran</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Jahanmehr, Nader; Rashidian, Arash; Khosravi, Ardeshir; Farzadfar, Farshad; Shariati, Mohammad; Majdzadeh, Reza; Sari, Ali Akbari; Mesdaghinia, Alireza</p> <p>2015-01-01</p> <p>Introduction: The main objective of this study was to design a conceptual framework, according to the policies and priorities of the ministry of health to evaluate provincial public health and <span class="hlt">primary</span> care performance and to assess their share in the overall health impacts of the community. Methods: We used several tools and techniques, including <span class="hlt">system</span> thinking, literature review to identify relevant attributes of health <span class="hlt">system</span> performance framework and interview with the key stakeholders. The PubMed, Scopus, web of science, Google Scholar and two specialized databases of Persian language literature (IranMedex and SID) were searched using main terms and keywords. Following decision-making and collective agreement among the different stakeholders, 51 core indicators were chosen from among 602 obtained indicators in a four stage process, for monitoring and evaluation of Health Deputies. Results: We proposed a conceptual framework by identifying the performance area for Health Deputies between other determinants of health, as well as introducing a chain of results, for performance, consisting of Input, Process, Output and Outcome indicators. We also proposed 5 dimensions for measuring the performance of Health Deputies, consisting of efficiency, effectiveness, equity, access and improvement of health status. Conclusion: The proposed Conceptual Framework illustrates clearly the Health Deputies success in achieving best results and consequences of health in the country. Having the relative commitment of the ministry of health and Health Deputies at the University of Medical Sciences is essential for full implementation of this framework and providing the annual performance report. PMID:25946937</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016NatGe...9..505R','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016NatGe...9..505R"><span>Partial decoupling of <span class="hlt">primary</span> productivity from upwelling in the California Current <span class="hlt">system</span></span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Renault, Lionel; Deutsch, Curtis; McWilliams, James C.; Frenzel, Hartmut; Liang, Jun-Hong; Colas, François</p> <p>2016-07-01</p> <p>Coastal winds and upwelling of deep nutrient-rich water along subtropical eastern boundaries yield some of the ocean's most productive ecosystems. Simple indices of coastal wind strength have been extensively used to estimate the timing and magnitude of biological productivity on seasonal and interannual timescales and underlie the prediction that anthropogenic climate warming will increase the productivity by making coastal winds stronger. The effect of wind patterns on regional net <span class="hlt">primary</span> productivity is not captured by such indices and is poorly understood. Here we present evidence, using a realistic model of the California Current <span class="hlt">system</span> and satellite measurements, that the observed slackening of the winds near the coast has little effect on near-shore phytoplankton productivity despite a large reduction in upwelling velocity. On the regional scale the wind drop-off leads to substantially higher production even when the total upwelling rate remains the same. This partial decoupling of productivity from upwelling results from the impact of wind patterns on alongshore currents and the eddies they generate. Our results imply that productivity in eastern boundary upwelling <span class="hlt">systems</span> will be better predicted from indices of the coastal wind that account for its offshore structure.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.osti.gov/scitech/servlets/purl/911384','SCIGOV-STC'); return false;" href="http://www.osti.gov/scitech/servlets/purl/911384"><span>Assessment of Field Experience Related to Pressurized Water Reactor <span class="hlt">Primary</span> <span class="hlt">System</span> Leaks</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Shah, Vikram Naginbhai; Ware, Arthur Gates; Atwood, Corwin Lee; Sattison, Martin Blaine; Hartley, Robert Scott; Hsu, C.</p> <p>1999-08-01</p> <p>This paper presents our assessment of field experience related to pressurized water reactor (PWR) <span class="hlt">primary</span> <span class="hlt">system</span> leaks in terms of their number of rates, how aging affects frequency of leak events, the safety significance of such leaks, industry efforts to reduce leaks, and effectiveness of current leak detection <span class="hlt">systems</span>. We have reviewed the licensee event reports to identify the events that took place during 1985 to the third quarter of 1996, and reviewed related technical literature and visited PWR plants to analyze these events. Our assessment shows that USNRC licensees have taken effective actions to reduce the number of leak events. One main reason for this decreasing trend was the elimination or reportable leakages from valve stem packing after 1991. Our review of leak events related to vibratory fatigue reveals a statistically significant decreasing trend with age (years of operation), but not in calendar time. Our assessment of worldwide data on leakage caused by thermal fatigue cracking is that the fatigue of aging piping is a safety significant issue. Our review of leak events has identified several susceptible sites in piping having high safety significance; but the inspection of some of these sites is not required by the ASME Code. These sites may be included in the risk-informed inspection programs.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.osti.gov/scitech/servlets/purl/9237','SCIGOV-STC'); return false;" href="http://www.osti.gov/scitech/servlets/purl/9237"><span>Assessment of Field Experience Related to Pressurized Water Reactor <span class="hlt">Primary</span> <span class="hlt">System</span> Leaks</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>A. G. Ware; C. Hsu; C. L. Atwood; M. B. Sattison; R. S. Hartley; V. N. Shah</p> <p>1999-02-01</p> <p>This paper presents our assessment of field experience related to pressurized water reactor (PWR) <span class="hlt">primary</span> <span class="hlt">system</span> leaks in terms of their number and rates, how aging affects frequency of leak events, the safety significance of such leaks, industry efforts to reduce leaks, and effectiveness of current leak detection <span class="hlt">systems</span>. We have reviewed the licensee event reports to identify the events that took place during 1985 to the third quarter of 1996, and reviewed related technical literature and visited PWR plants to analyze these events. Our assessment shows that USNRC licensees have taken effective actions to reduce the number of leak events. One main reason for this decreasing trend was the elimination or reportable leakages from valve stem packing after 1991. Our review of leak events related to vibratory fatigue reveals a statistically significant decreasing trend with age (years of operation), but not in calendar time. Our assessment of worldwide data on leakage caused by thermal fatigue cracking is that the fatigue of aging piping is a safety significant issue. Our review of leak events has identified several susceptible sites in piping having high safety significance; but the inspection of some of these sites is not required by the ASME Code. These sites may be included in the risk-informed inspection programs.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.mayoclinic.org/diseases-conditions/primary-progressive-aphasia/home/ovc-20168153?p=1','NIH-MEDLINEPLUS'); return false;" href="http://www.mayoclinic.org/diseases-conditions/primary-progressive-aphasia/home/ovc-20168153?p=1"><span><span class="hlt">Primary</span> Progressive Aphasia</span></a></p> <p><a target="_blank" href="http://medlineplus.gov/">MedlinePlus</a></p> <p></p> <p></p> <p><span class="hlt">Primary</span> progressive aphasia Overview By Mayo Clinic Staff <span class="hlt">Primary</span> progressive aphasia (uh-FAY-zhuh) is a rare nervous <span class="hlt">system</span> (neurological) syndrome ... your ability to communicate. People with <span class="hlt">primary</span> progressive aphasia can have trouble expressing their thoughts and understanding ...</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_17");'>17</a></li> <li><a href="#" onclick='return showDiv("page_18");'>18</a></li> <li class="active"><span>19</span></li> <li><a href="#" onclick='return showDiv("page_20");'>20</a></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_19 --> <div id="page_20" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_18");'>18</a></li> <li><a href="#" onclick='return showDiv("page_19");'>19</a></li> <li class="active"><span>20</span></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li><a href="#" onclick='return showDiv("page_22");'>22</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="381"> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/scitech/biblio/1130193','SCIGOV-STC'); return false;" href="https://www.osti.gov/scitech/biblio/1130193"><span>Displacement Threshold Energy and Recovery in an <span class="hlt">Al</span>-Ti Nanolayered <span class="hlt">System</span> with Intrinsic Point Defect Partitioning</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Gerboth, Matthew D.; Setyawan, Wahyu; Henager, Charles H.</p> <p>2014-01-07</p> <p>A method is established and validated using molecular dynamics (MD) to determine the displacement threshold energies as Ed in nanolayered, multilayered <span class="hlt">systems</span> of dissimilar metals. The method is applied to specifically oriented nanolayered films of <span class="hlt">Al</span>-Ti where the crystal structure and interface orientations are varied in atomic models and Ed is calculated. Methods for defect detection are developed and discussed based on prior research in the literature and based on specific crystallographic directions available in the nanolayered <span class="hlt">systems</span>. These are compared and contrasted to similar calculations in corresponding bulk materials, including fcc <span class="hlt">Al</span>, fcc Ti, hcp <span class="hlt">Al</span>, and hcp Ti. In all cases, the calculated Ed in the multilayers are intermediate to the corresponding bulk values but exhibit some important directionality. In the nanolayer, defect detection demonstrated systematic differences in the behavior of Ed in each layer. Importantly, collision cascade damage exhibits significant defect partitioning within the <span class="hlt">Al</span> and Ti layers that is hypothesized to be an intrinsic property of dissimilar nanolayered <span class="hlt">systems</span>. This type of partitioning could be partly responsible for observed asymmetric radiation damage responses in many multilayered <span class="hlt">systems</span>. In addition, a pseudo-random direction was introduced to approximate the average Ed without performing numerous simulations with random directions.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://hdl.handle.net/2060/20060051711','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/20060051711"><span>A Preliminary Assessment of Phase Separator Ground-Based and Reduced-Gravity Testing for <span class="hlt">ALS</span> <span class="hlt">Systems</span></span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Hall, Nancy Rabel</p> <p>2006-01-01</p> <p>A viewgraph presentation of phase separator ground-based and reduced-gravity testing for Advanced Life Support (<span class="hlt">ALS</span>) <span class="hlt">systems</span> is shown. The topics include: 1) Multiphase Flow Technology Program; 2) Types of Separators; 3) MOBI Phase Separators; 4) Experiment set-up; and 5) Preliminary comparison/results.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.gpo.gov/fdsys/pkg/FR-2010-10-01/pdf/2010-24624.pdf','FEDREG'); return false;" href="https://www.gpo.gov/fdsys/pkg/FR-2010-10-01/pdf/2010-24624.pdf"><span>75 FR 60820 - United States v. Adobe <span class="hlt">Systems</span>, Inc., et <span class="hlt">al</span>.; Proposed Final Judgment and Competitive Impact...</span></a></p> <p><a target="_blank" href="http://www.gpo.gov/fdsys/browse/collection.action?collectionCode=FR">Federal Register 2010, 2011, 2012, 2013, 2014</a></p> <p></p> <p>2010-10-01</p> <p>... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF JUSTICE Antitrust Division United States v. Adobe <span class="hlt">Systems</span>, Inc., et <span class="hlt">al</span>.; Proposed Final Judgment and Competitive Impact Statement Notice is hereby given pursuant to the Antitrust Procedures and Penalties Act, 15 U.S.C. 16(b)-(h), that a proposed Final...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016JPCM...28q5302D','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016JPCM...28q5302D"><span>A basin-hopping Monte Carlo investigation of the structural and energetic properties of 55- and 561-atom bimetallic nanoclusters: the examples of the ZrCu, Zr<span class="hlt">Al</span>, and Cu<span class="hlt">Al</span> <span class="hlt">systems</span></span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>De Souza, Douglas G.; Cezar, Henrique M.; Rondina, Gustavo G.; de Oliveira, Marcelo F.; Da Silva, Juarez L. F.</p> <p>2016-05-01</p> <p>We report a basin-hopping Monte Carlo investigation within the embedded-atom method of the structural and energetic properties of bimetallic ZrCu, Zr<span class="hlt">Al</span>, and Cu<span class="hlt">Al</span> nanoclusters with 55 and 561 atoms. We found that unary Zr55, Zr561, Cu55, Cu561, <span class="hlt">Al</span>55, and <span class="hlt">Al</span>561 <span class="hlt">systems</span> adopt the well known compact icosahedron (ICO) structure. The excess energy is negative for all <span class="hlt">systems</span> and compositions, which indicates an energetic preference for the mixing of both chemical species. The ICO structure is preserved if a few atoms of the host <span class="hlt">system</span> are replaced by different species, however, the composition limit in which the ICO structure is preserved depends on both the host and new chemical species. Using several structural analyses, three classes of structures, namely ideal ICO, nearly ICO, and distorted ICO structures, were identified. As the amounts of both chemical species change towards a more balanced composition, configurations far from the ICO structure arise and the dominant structures are nearly spherical, which indicates a strong minimization of the surface energy by decreasing the number of atoms with lower coordination on the surface. The average bond lengths follow Vegard’s law almost exactly for ZrCu and Zr<span class="hlt">Al</span>, however, this is not the case for Cu<span class="hlt">Al</span>. Furthermore, the radial distribution allowed us to identify the presence of an onion-like behavior in the surface of the 561-atom Cu<span class="hlt">Al</span> nanocluster with the <span class="hlt">Al</span> atoms located in the outermost surface shell, which can be explained by the lower surface energies of the <span class="hlt">Al</span> surfaces compared with the Cu surfaces. In ZrCu and Zr<span class="hlt">Al</span> the radial distribution indicates a nearly homogeneous distribution for the chemical species, however, with a slightly higher concentration of <span class="hlt">Al</span> atoms on the Zr<span class="hlt">Al</span> surface, which can also be explained by the lower surface energy.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2009PhRvB..80t5412D','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2009PhRvB..80t5412D"><span>Complex metallic surface phases in the <span class="hlt">Al</span>/Cu(111) <span class="hlt">system</span>: An experimental and computational study</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Duguet, T.; Gaudry, E.; Deniozou, T.; Ledieu, J.; de Weerd, M. C.; Belmonte, T.; Dubois, J. M.; Fournée, V.</p> <p>2009-11-01</p> <p>The growth of complex intermetallics as surface alloys is investigated by annealing <span class="hlt">Al</span> thin films deposited on Cu(111) substrate in ultrahigh vacuum. Already at room temperature, the large lattice mismatch between <span class="hlt">Al</span> and Cu results in interfacial intermixing. Upon annealing, various phases are formed by diffusion depending on the thickness of the <span class="hlt">Al</span> films and the annealing temperature. The surface structures are characterized by scanning tunneling microscopy, low-energy electron diffraction, and x-ray photoelectron spectroscopy. Three different superlattice phases are identified as well as the complex Hume-Rothery γ-<span class="hlt">Al</span>4Cu9 phase. The epitaxial relationships between the surface phases and the Cu(111) substrate are determined. We further investigate the electronic structure of the γ phase by density functional calculations. Experimental valence bands are compared to calculated density of states and simulated STM images are used to identify possible bulk planes appearing as surface termination.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2008RuMet2008...46P','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2008RuMet2008...46P"><span>Rare-earth metals (REMs) in nickel aluminide-based alloys: I. Physicochemical laws of interaction in the Ni-<span class="hlt">Al</span>-REM and Ni x <span class="hlt">Al</span> y -REM-AE (alloying element) <span class="hlt">systems</span></span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Povarova, K. B.; Kazanskaya, N. K.; Drozdov, A. A.; Morozov, A. E.</p> <p>2008-02-01</p> <p>The data on the Ni-<span class="hlt">Al</span>- R ( R = REM Sc, Y, La, lanthanides) binary and ternary <span class="hlt">systems</span> and the interactions of three rare-earth metals (yttrium, lanthanum, cerium) with the main alloying elements (Ti (Zr, Hf), Cr (Mo, W) that are introduced into Ni3<span class="hlt">Al</span>-based VKNA alloys are analyzed. The binary aluminides of REMs in the Ni-<span class="hlt">Al</span>- R ternary <span class="hlt">systems</span> are shown to be in equilibrium with neither Ni<span class="hlt">Al</span> nor Ni3<span class="hlt">Al</span>. The solid solution of aluminum in RNi5, which penetrates deep into these ternary <span class="hlt">systems</span>, is the most stable phase in equilibrium with Ni3<span class="hlt">Al</span>. In the Ni<span class="hlt">Al</span> (Ni3<span class="hlt">Al</span>)-AE- R <span class="hlt">systems</span>, REM precipitation (segregation) on various defects and interfaces in nickel aluminides is likely to be the most probable, and REMs are thought to interact with the most active impurities in real alloys (C, O, N), since REMs have a large atomic radius and, thus, are virtually undissolved in nickel, aluminum, and nickel aluminides.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://hdl.handle.net/2060/19920000799','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/19920000799"><span>Feasibility of using a knowledge-based <span class="hlt">system</span> concept for in-flight <span class="hlt">primary</span> flight display research</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Ricks, Wendell R.</p> <p>1991-01-01</p> <p>A study was conducted to determine the feasibility of using knowledge-based <span class="hlt">systems</span> architectures for inflight research of <span class="hlt">primary</span> flight display information management issues. The feasibility relied on the ability to integrate knowledge-based <span class="hlt">systems</span> with existing onboard aircraft <span class="hlt">systems</span>. And, given the hardware and software platforms available, the feasibility also depended on the ability to use interpreted LISP software with the real time operation of the <span class="hlt">primary</span> flight display. In addition to evaluating these feasibility issues, the study determined whether the software engineering advantages of knowledge-based <span class="hlt">systems</span> found for this application in the earlier workstation study extended to the inflight research environment. To study these issues, two integrated knowledge-based <span class="hlt">systems</span> were designed to control the <span class="hlt">primary</span> flight display according to pre-existing specifications of an ongoing <span class="hlt">primary</span> flight display information management research effort. These two <span class="hlt">systems</span> were implemented to assess the feasibility and software engineering issues listed. Flight test results were successful in showing the feasibility of using knowledge-based <span class="hlt">systems</span> inflight with actual aircraft data.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27441838','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27441838"><span>Metabolic Profiling of <span class="hlt">Systemic</span> Lupus Erythematosus and Comparison with <span class="hlt">Primary</span> Sjögren's Syndrome and <span class="hlt">Systemic</span> Sclerosis.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Bengtsson, Anders A; Trygg, Johan; Wuttge, Dirk M; Sturfelt, Gunnar; Theander, Elke; Donten, Magdalena; Moritz, Thomas; Sennbro, Carl-Johan; Torell, Frida; Lood, Christian; Surowiec, Izabella; Rännar, Stefan; Lundstedt, Torbjörn</p> <p>2016-01-01</p> <p><span class="hlt">Systemic</span> lupus erythematosus (SLE) is a chronic inflammatory autoimmune disease which can affect most organ <span class="hlt">systems</span> including skin, joints and the kidney. Clinically, SLE is a heterogeneous disease and shares features of several other rheumatic diseases, in particular <span class="hlt">primary</span> Sjögrens syndrome (pSS) and <span class="hlt">systemic</span> sclerosis (SSc), why it is difficult to diagnose The pathogenesis of SLE is not completely understood, partly due to the heterogeneity of the disease. This study demonstrates that metabolomics can be used as a tool for improved diagnosis of SLE compared to other similar autoimmune diseases. We observed differences in metabolic profiles with a classification specificity above 67% in the comparison of SLE with pSS, SSc and a matched group of healthy individuals. Selected metabolites were also significantly different between studied diseases. Biochemical pathway analysis was conducted to gain understanding of underlying pathways involved in the SLE pathogenesis. We found an increased oxidative activity in SLE, supported by increased xanthine oxidase activity and an increased turnover in the urea cycle. The most discriminatory metabolite observed was tryptophan, with decreased levels in SLE patients compared to control groups. Changes of tryptophan levels were related to changes in the activity of the aromatic amino acid decarboxylase (AADC) and/or to activation of the kynurenine pathway.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4956266','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4956266"><span>Metabolic Profiling of <span class="hlt">Systemic</span> Lupus Erythematosus and Comparison with <span class="hlt">Primary</span> Sjögren’s Syndrome and <span class="hlt">Systemic</span> Sclerosis</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Bengtsson, Anders A.; Trygg, Johan; Wuttge, Dirk M.; Sturfelt, Gunnar; Theander, Elke; Donten, Magdalena; Moritz, Thomas; Sennbro, Carl-Johan; Torell, Frida; Lood, Christian; Surowiec, Izabella; Rännar, Stefan; Lundstedt, Torbjörn</p> <p>2016-01-01</p> <p><span class="hlt">Systemic</span> lupus erythematosus (SLE) is a chronic inflammatory autoimmune disease which can affect most organ <span class="hlt">systems</span> including skin, joints and the kidney. Clinically, SLE is a heterogeneous disease and shares features of several other rheumatic diseases, in particular <span class="hlt">primary</span> Sjögrens syndrome (pSS) and <span class="hlt">systemic</span> sclerosis (SSc), why it is difficult to diagnose The pathogenesis of SLE is not completely understood, partly due to the heterogeneity of the disease. This study demonstrates that metabolomics can be used as a tool for improved diagnosis of SLE compared to other similar autoimmune diseases. We observed differences in metabolic profiles with a classification specificity above 67% in the comparison of SLE with pSS, SSc and a matched group of healthy individuals. Selected metabolites were also significantly different between studied diseases. Biochemical pathway analysis was conducted to gain understanding of underlying pathways involved in the SLE pathogenesis. We found an increased oxidative activity in SLE, supported by increased xanthine oxidase activity and an increased turnover in the urea cycle. The most discriminatory metabolite observed was tryptophan, with decreased levels in SLE patients compared to control groups. Changes of tryptophan levels were related to changes in the activity of the aromatic amino acid decarboxylase (AADC) and/or to activation of the kynurenine pathway. PMID:27441838</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.dtic.mil/docs/citations/ADA575213','DTIC-ST'); return false;" href="http://www.dtic.mil/docs/citations/ADA575213"><span>Ignition and Combustion Characteristics of Nanoscale <span class="hlt">Al</span>/AgIO3: A Potential Energetic Biocidal <span class="hlt">System</span></span></a></p> <p><a target="_blank" href="https://publicaccess.dtic.mil/psm/api/service/search/search">DTIC Science & Technology</a></p> <p></p> <p>2011-01-01</p> <p>reaction of <span class="hlt">Al</span>/AgIO3 thermites for potential use in biocidal applications . Rapid-heating wire experiments were performed to measure the ignition...OF: This work investigates the ignition and reaction of <span class="hlt">Al</span>/AgIO3 thermites for potential use in biocidal applications . Rapid-heating wire experiments...were performed to measure the ignition temperature and investigate the thermal decomposition of the oxidizer using a T-Jump/TOF Mass Spectrometer</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017JQSRT.187..167S','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017JQSRT.187..167S"><span>The new investigation of the b3Σ- -a3 Π <span class="hlt">system</span> of <span class="hlt">Al</span>H</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Szajna, Wojciech; Hakalla, Rafał; Kolek, Przemysław; Zachwieja, Mirosław</p> <p>2017-01-01</p> <p>The b3Σ- -a3 Π visible <span class="hlt">system</span> of <span class="hlt">Al</span>H was observed at high resolution by using a high accuracy, dispersive optical spectroscopy technique. The emission spectrum was excited in an aluminum hollow-cathode lamp with two anodes, filled with a static Ne/NH3 gas mixture. In the 25 , 900 - 26 , 500cm-1 spectral region, the rotational structure of the two overlapped 0-0 and 1-1 bands was clearly observed and precisely measured. In total, 260 transition wavenumbers have been assigned with an estimated accuracy of about 0.005 cm-1. The open rotational structure of the Q branches in both bands has been measured for the first time, and the Λ-doubling in the a3 Π , v = 0 , 1 levels has been described by o , p and q parameters. For example, the values for the v = 0 level are p0 = 1.754 (14) ×10-2cm-1, q0 = 3.264 (28) ×10-3cm-1 and o0 = 9.34 (20) ×10-2cm-1. Moreover, the spin-orbit interaction constants for the a3 Π state have been obtained experimentally as follows: A0 = 40.6040 (42)cm-1 and A1 = 40.419 (59)cm-1. The a3 Π , v = 0 , 1 levels are considered as regular, while for the b3Σ- , v = 0 , 1 levels considerable perturbations in the rotational structure have been observed. Consequently, these states have been represented in a different way in our least-squares treatment: a3 Π state by molecular constants and b3Σ- state by term values. The observed irregularities in the b3Σ- state have been graphically described by plotting experimental minus calculated term values versus quantum number N for the v = 0 level, as well as by plotting reduced term values versus N (N + 1) for the v = 1 level.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28277869','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28277869"><span>Disease burden of <span class="hlt">systemic</span> light-chain (<span class="hlt">AL</span>) amyloidosis: a systematic literature review.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Lin, Huamao Mark; Gao, Xin; Cooke, Catherine E; Berg, Deborah; Labotka, Richard; Faller, Douglas V; Seal, Brian; Hari, Parameswaran</p> <p>2017-02-21</p> <p>A systematic literature review on <span class="hlt">AL</span> amyloidosis was conducted in order to understand the disease burden, and identify unmet medical needs and knowledge gaps. MEDLINE, EMBASE and COCHRANE databases were searched for English language studies published in the last 10 years using search terms that focused on the clinical, economic, and patient-reported outcome (PRO) aspects of <span class="hlt">AL</span> amyloidosis. There was a low yield of articles in the economic and PRO categories and additional searches were conducted in clinical conference proceedings, and using Google and Google Scholar. After review, there were 65 articles included for data extraction. <span class="hlt">AL</span> amyloidosis is a rare disorder without any FDA or EMA approved indications for drug therapy. Using off-label therapies, there is a high rate, 42-64%, of non-response or progression, and an associated high mortality. Toxicities during therapy are common with estimates of up to 30-40% of patients experiencing severity of grade 3 or higher. Patients with <span class="hlt">AL</span> amyloidosis report severe psychological distress, anxiety and clinical depression. There is a deficiency in the literature on the economic costs associated with <span class="hlt">AL</span> amyloidosis, and information on costs has been derived from studies that examined multiple myeloma or other disease or treatment components common to <span class="hlt">AL</span> amyloidosis.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015IJAEO..43..160H','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015IJAEO..43..160H"><span>Leaf chlorophyll constraint on model simulated gross <span class="hlt">primary</span> productivity in agricultural <span class="hlt">systems</span></span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Houborg, Rasmus; McCabe, Matthew F.; Cescatti, Alessandro; Gitelson, Anatoly A.</p> <p>2015-12-01</p> <p>Leaf chlorophyll content (Chll) may serve as an observational proxy for the maximum rate of carboxylation (Vmax), which describes leaf photosynthetic capacity and represents the single most important control on modeled leaf photosynthesis within most Terrestrial Biosphere Models (TBMs). The parameterization of Vmax is associated with great uncertainty as it can vary significantly between plants and in response to changes in leaf nitrogen (N) availability, plant phenology and environmental conditions. Houborg et <span class="hlt">al</span>. (2013) outlined a semi-mechanistic relationship between Vmax25 (Vmax normalized to 25 °C) and Chll based on inter-linkages between Vmax25, Rubisco enzyme kinetics, N and Chll. Here, these relationships are parameterized for a wider range of important agricultural crops and embedded within the leaf photosynthesis-conductance scheme of the Community Land Model (CLM), bypassing the questionable use of temporally invariant and broadly defined plant functional type (PFT) specific Vmax25 values. In this study, the new Chll constrained version of CLM is refined with an updated parameterization scheme for specific application to soybean and maize. The benefit of using in-situ measured and satellite retrieved Chll for constraining model simulations of Gross <span class="hlt">Primary</span> Productivity (GPP) is evaluated over fields in central Nebraska, U.S.A between 2001 and 2005. Landsat-based Chll time-series records derived from the Regularized Canopy Reflectance model (REGFLEC) are used as forcing to the CLM. Validation of simulated GPP against 15 site-years of flux tower observations demonstrate the utility of Chll as a model constraint, with the coefficient of efficiency increasing from 0.91 to 0.94 and from 0.87 to 0.91 for maize and soybean, respectively. Model performances particularly improve during the late reproductive and senescence stage, where the largest temporal variations in Chll (averaging 35-55 μg cm-2 for maize and 20-35 μg cm-2 for soybean) are observed. While</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/24177246','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/24177246"><span>Sleep misperception, EEG characteristics and autonomic nervous <span class="hlt">system</span> activity in <span class="hlt">primary</span> insomnia: a retrospective study on polysomnographic data.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Maes, J; Verbraecken, J; Willemen, M; De Volder, I; van Gastel, A; Michiels, N; Verbeek, I; Vandekerckhove, M; Wuyts, J; Haex, B; Willemen, T; Exadaktylos, V; Bulckaert, A; Cluydts, R</p> <p>2014-03-01</p> <p>Misperception of Sleep Onset Latency, often found in <span class="hlt">Primary</span> Insomnia, has been cited to be influenced by hyperarousal, reflected in EEG- and ECG-related indices. The aim of this retrospective study was to examine the association between Central Nervous <span class="hlt">System</span> (i.e. EEG) and Autonomic Nervous <span class="hlt">System</span> activity in the Sleep Onset Period and the first NREM sleep cycle in <span class="hlt">Primary</span> Insomnia (n=17) and healthy controls (n=11). Furthermore, the study examined the influence of elevated EEG and Autonomic Nervous <span class="hlt">System</span> activity on Stage2 sleep-protective mechanisms (K-complexes and sleep spindles). Confirming previous findings, the <span class="hlt">Primary</span> Insomnia-group overestimated Sleep Onset Latency and this overestimation was correlated with elevated EEG activity. A higher amount of beta EEG activity during the Sleep Onset Period was correlated with the appearance of K-complexes immediately followed by a sleep spindle in the <span class="hlt">Primary</span> Insomnia-group. This can be interpreted as an extra attempt to protect sleep continuity or as a failure of the sleep-protective role of the K-complex by fast EEG frequencies following within one second. The strong association found between K-alpha (K-complex within one second followed by 8-12 Hz EEG activity) in Stage2 sleep and a lower parasympathetic Autonomic Nervous <span class="hlt">System</span> dominance (less high frequency HR) in Slow-wave sleep, further assumes a state of hyperarousal continuing through sleep in <span class="hlt">Primary</span> Insomnia.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2825883','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2825883"><span>Model <span class="hlt">Systems</span> for Examining Effects of Leukemia-Associated Oncogenes in <span class="hlt">Primary</span> Human CD34+ Cells via Retroviral Transduction</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Wunderlich, Mark; Mulloy, James C.</p> <p>2010-01-01</p> <p>Summary The use of <span class="hlt">primary</span> human cells to model cancer initiation and progression is now within the grasp of investigators. It has been nearly a decade since the first defined genetic elements were introduced into <span class="hlt">primary</span> human epithelial and fibroblast cells to model oncogenesis. This approach has now been extended to the hematopoietic <span class="hlt">system</span>, with the first described experimental transformation of <span class="hlt">primary</span> human hematopoietic cells. Human cell model <span class="hlt">systems</span> will lead to a better understanding of the species and cell type specific signals necessary for oncogenic initiation and progression, and will allow investigators to interrogate the cancer stem cell hypothesis using a well-defined hierarchical <span class="hlt">system</span> that has been studied for decades. The molecular and biochemical link between self-renewal and differentiation can now be experimentally approached using <span class="hlt">primary</span> human cells. In addition, the models that result from these experiments are likely to generate highly relevant <span class="hlt">systems</span> for use in identification and validation of potential therapeutic targets as well as testing of small molecule therapeutics. We describe here the methodologies and reagents that are used to examine the effects of leukemia fusion protein expression on <span class="hlt">primary</span> human hematopoietic cells, both in vitro and in vivo. PMID:19277588</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27918401','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27918401"><span>Establishing a Viable Workforce Pipeline of <span class="hlt">Primary</span> Care Nurse Practitioners: Benefits of a Health <span class="hlt">System</span> and Academic Partnership.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Madler, Billie; Helland, Mary</p> <p></p> <p>Maldistribution and shortages of <span class="hlt">primary</span> care providers, changing reimbursement structures, movement from inpatient to community-based models of care, an aging population, and health care reform lead to increased numbers of patients seeking care. All of these phenomena have a part in creating a health care landscape that requires industry leaders enlist innovative strategies to meet the health care needs of their communities. Delivery of high-quality, efficient care by qualified providers is essential for the success of any health care <span class="hlt">system</span>. Partnerships between health <span class="hlt">systems</span> and academic centers of learning to develop a pipeline of providers is one inventive approach that can address <span class="hlt">primary</span> care workforce needs. The purpose of this article was to share an example of an academic/health care <span class="hlt">system</span> partnership to address <span class="hlt">primary</span> care workforce needs in a rural Midwestern region.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016MNRAS.460.1811S','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016MNRAS.460.1811S"><span>HD 35502: a hierarchical triple <span class="hlt">system</span> with a magnetic B5IVpe <span class="hlt">primary</span></span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Sikora, J.; Wade, G. A.; Bohlender, D. A.; Shultz, M.; Adelman, S. J.; Alecian, E.; Hanes, D.; Monin, D.; Neiner, C.; MiMeS Collaboration; BinaMIcS Collaboration</p> <p>2016-08-01</p> <p>We present our analysis of HD 35502 based on high- and medium-resolution spectropolarimetric observations. Our results indicate that the magnetic B5IVsnp star is the <span class="hlt">primary</span> component of a spectroscopic triple <span class="hlt">system</span> and that it has an effective temperature of 18.4 ± 0.6 kK, a mass of 5.7 ± 0.6 M⊙, and a polar radius of 3.0^{+1.1}_{-0.5} R_{odot }. The two secondary components are found to be essentially identical A-type stars for which we derive effective temperatures (8.9 ± 0.3 kK), masses (2.1 ± 0.2 M⊙), and radii (2.1 ± 0.4 R⊙). We infer a hierarchical orbital configuration for the <span class="hlt">system</span> in which the secondary components form a tight binary with an orbital period of 5.668 66(6) d that orbits the <span class="hlt">primary</span> component with a period of over 40 yr. Least-Squares Deconvolution profiles reveal Zeeman signatures in Stokes V indicative of a longitudinal magnetic field produced by the B star ranging from approximately -4 to 0 kG with a median uncertainty of 0.4 kG. These measurements, along with the line variability produced by strong emission in Hα, are used to derive a rotational period of 0.853 807(3) d. We find that the measured v sin i = 75 ± 5 km s-1 of the B star then implies an inclination angle of the star's rotation axis to the line of sight of 24^{+6}_{-10}{}^circ. Assuming the Oblique Rotator Model, we derive the magnetic field strength of the B star's dipolar component (14^{+9}_{-3} kG) and its obliquity (63± 13deg). Furthermore, we demonstrate that the calculated Alfvén radius (41^{+17}_{-6}R_ast) and Kepler radius (2.1^{+0.4}_{-0.7}R_ast) place HD 35502's central B star well within the regime of centrifugal magnetosphere-hosting stars.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://pubs.er.usgs.gov/publication/70014774','USGSPUBS'); return false;" href="http://pubs.er.usgs.gov/publication/70014774"><span>Heat capacity measurements for cryolite (Na3<span class="hlt">Al</span>F6) and reactions in the <span class="hlt">system</span> NaFe<span class="hlt">Al</span>SiOF</span></a></p> <p><a target="_blank" href="http://pubs.er.usgs.gov/pubs/index.jsp?view=adv">USGS Publications Warehouse</a></p> <p>Anovitz, Lawrence M.; Hemingway, B.S.; Westrum, E.F.; Metz, G.W.; Essene, E.J.</p> <p>1987-01-01</p> <p>The heat capacity of cryolite (Na3<span class="hlt">Al</span>F6) has been measured from 7 to 1000 K by low-temperature adiabatic and high-temperature differential scanning calorimetry. Low-temperature data were obtained on material from the same hand specimen in the calorimetric laboratories of the University of Michigan and U.S. Geological Survey. The results obtained are in good agreement, and yield average values for the entropy of cryolite of: S0298 = 238.5 J/mol KS0T-S0298 = 145.114 ln T+ 193.009*10-3T- 10.366* 105 T2- 872.89 J/mol K (273-836.5 K)??STrans = 9.9J/mol KS0T-S0298 =198.414 ln T+73.203* 10-3T-63.814* 105 T2-1113.11 J/mol K (836.5-1153 K) with the transition temperature between ??- and ??-cryolite taken at 836.5 K. These data have been combined with data in the literature to calculate phase equilibria for the <span class="hlt">system</span> NaFe<span class="hlt">Al</span>SiOF. The resultant phase diagrams allow constraints to be placed on the fO2, fF2, aSiO2 and T conditions of formation for assemblages in alkalic rocks. A sample application suggests that log fO2 is approximately -19.2, log fF2 is -31.9 to -33.2, and aSiO2 is -1.06 at assumed P T conditions of 1000 K, 1 bar for the villiaumite-bearing Ilimaussaq intrusion in southwestern Greenland. ?? 1987.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27103761','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27103761"><span>Re-investigation of phase equilibria in the <span class="hlt">system</span> <span class="hlt">Al</span>-Cu and structural analysis of the high-temperature phase η1-<span class="hlt">Al</span>1-δCu.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Ponweiser, Norbert; Lengauer, Christian L; Richter, Klaus W</p> <p>2011-11-01</p> <p>The phase equilibria and reaction temperatures in the <span class="hlt">system</span> <span class="hlt">Al</span>-Cu were re-investigated by a combination of optical microscopy, powder X-ray diffraction (XRD) at ambient and elevated temperature, differential thermal analysis (DTA) and scanning electron microscopy (SEM). A full description of the phase diagram is given. The phase equilibria and invariant reactions in the Cu-poor part of the phase diagram could be confirmed. The Cu-rich part shows some differences in phase equilibria and invariant reactions compared to the known phase diagram. A two phase field was found between the high temperature phase η1 and the low temperature phase η2 thus indicating a first order transition. In the ζ1/ζ2 region of the phase diagram recent findings on the thermal stability could be widely confirmed. Contrary to previous results, the two phase field between δ and γ1 is very narrow. The results of the current work indicate the absence of the high temperature β0 phase as well as the absence of a two phase field between γ1 and γ0 suggesting a higher order transition between γ1 and γ0. The structure of γ0 (I-43m, Cu5Zn8-type) was confirmed by means of high-temperature XRD. Powder XRD was also used to determine the structure of the high temperature phase η1-<span class="hlt">Al</span>1-δCu. The phase is orthorhombic (space group Cmmm) and the lattice parameters are a = 4.1450(1) Å, b = 12.3004(4) Å and c = 8.720(1) Å; atomic coordinates are given.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/scitech/biblio/22492517','SCIGOV-STC'); return false;" href="https://www.osti.gov/scitech/biblio/22492517"><span>Study of the magnetic properties, structure, and phase transformation in the alloys of the Co-<span class="hlt">Al</span>-W <span class="hlt">system</span></span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Davidov, D. I. Stepanova, N. N. Kazantseva, N. V. Rigmant, M. B. Shishkin, D. A.</p> <p>2015-10-27</p> <p>An experimental study of phase transformations in the <span class="hlt">system</span> of Co-<span class="hlt">Al</span>-W in the concentration area of the intermetallic compound Co{sub 3}(<span class="hlt">Al</span>, W) is presented. The structure and phase composition of the Co–9 at % Al–X at % W (X = 4.5, 6.8, 8.5, 10, 12.5) alloys in depending on the tungsten content are analyzed. The Curie temperature and magnetic properties of the alloys with the different phase composition are determined.</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_18");'>18</a></li> <li><a href="#" onclick='return showDiv("page_19");'>19</a></li> <li class="active"><span>20</span></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li><a href="#" onclick='return showDiv("page_22");'>22</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_20 --> <div id="page_21" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_19");'>19</a></li> <li><a href="#" onclick='return showDiv("page_20");'>20</a></li> <li class="active"><span>21</span></li> <li><a href="#" onclick='return showDiv("page_22");'>22</a></li> <li><a href="#" onclick='return showDiv("page_23");'>23</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="401"> <li> <p><a target="_blank" onclick="trackOutboundLink('http://hdl.handle.net/2060/19850007569','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/19850007569"><span>Optimization of the NiCr<span class="hlt">Al</span>-Y/ZrO-Y2O3 thermal barrier <span class="hlt">system</span></span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Stecura, S.</p> <p>1985-01-01</p> <p>The effects of bond and thermal barrier coating compositions, thicknesses, and densities on air plasma spray deposited Ni-Cr-<span class="hlt">Al</span>-Y/ZrO2-Y2O3 life were evaluated in cyclic furnace oxidation tests at temperatures from 1110 to 1220 C. An empirical relation was developed to give life as a function of the above parameters. The thermal barrier <span class="hlt">system</span> tested which had the longest life consisted of Ni-35.0 wt% Cr-5.9 wt% <span class="hlt">Al</span>-0.95 wt% Y bond coating and ZrO2-6.1 wt% Y2O3 thermal barrier coating.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2007SSSci...9..531A','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2007SSSci...9..531A"><span>[H 4tren] 3/2·(<span class="hlt">Al</span> 6F 24)·3H 2O, the most condensed fluoride in the <span class="hlt">Al</span>(OH) 3- tren-HF aq.-ethanol <span class="hlt">system</span></span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Adil, K.; Marrot, J.; Leblanc, M.; Maisonneuve, V.</p> <p>2007-06-01</p> <p>The most condensed crystalline fluoride that appears in the <span class="hlt">Al</span>(OH) 3- tren-HF aq.-ethanol <span class="hlt">system</span> at 190 °C is found to be [H 4tren] 3/2·(<span class="hlt">Al</span> 6F 24)·3H 2O. The structure is monoclinic, P2 1/ c, with a = 21.939(1) Å, b = 6.7180(2) Å, c = 23.329(1) Å, β = 111.324(2)°. ∞(<span class="hlt">Al</span> 6F 24) chains result from the connection of (<span class="hlt">Al</span> 7F 30) 9- polyanions by opposite <span class="hlt">Al</span>F 6 octahedra. Hydrogen bonds are established between the ∞(<span class="hlt">Al</span> 6F 24) chains and ordered or disordered [H 4tren] 4+ cations and water molecules.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.osti.gov/scitech/servlets/purl/1185327','SCIGOV-STC'); return false;" href="http://www.osti.gov/scitech/servlets/purl/1185327"><span>Metastability in the Mg<span class="hlt">Al</span><sub>2</sub>O<sub>4</sub>-<span class="hlt">Al</span><sub>2</sub>O<sub>3</sub> <span class="hlt">System</span></span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Wilkerson, Kelley R.; Smith, Jeffrey D.; Hemrick, James G.</p> <p>2014-07-22</p> <p>Aluminum oxide must take a spinel form ( γ-<span class="hlt">Al</span><sub>2</sub>O<sub>3</sub>) at elevated temperatures in order for extensive solid solution to form between Mg<span class="hlt">Al</span><sub>2</sub>O<sub>4</sub> and α-<span class="hlt">Al</span><sub>2</sub>O<sub>3</sub>. The solvus line between Mg<span class="hlt">Al</span><sub>2</sub>O<sub>4</sub> and <span class="hlt">Al</span><sub>2</sub>O<sub>3</sub> has been defined at 79.6 wt% <span class="hlt">Al</span><sub>2</sub>O<sub>3</sub> at 1500°C, 83.0 wt% <span class="hlt">Al</span><sub>2</sub>O<sub>3</sub> at 1600°C, and 86.5 wt% <span class="hlt">Al</span><sub>2</sub>O<sub>3</sub> at 1700°C. A metastable region has been defined at temperatures up to 1700°C which could have significant implications for material processing and properties. Additionally, initial processing could have major implications on final chemistry. The spinel solid solution region has been extended to form an infinite solid solution with <span class="hlt">Al</span><sub>2</sub>O<sub>3</sub> at elevated temperatures. A minimum in melting at 1975°C and a chemistry of 96 wt% <span class="hlt">Al</span><sub>2</sub>O<sub>3</sub> rather than a eutectic is present, resulting in no eutectic crystal formation during solidification.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4049900','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4049900"><span>Meckel-Gruber syndrome and the role of <span class="hlt">primary</span> cilia in kidney, skeleton, and central nervous <span class="hlt">system</span> development</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Barker, Amy R; Thomas, Rhys; Dawe, Helen R</p> <p>2014-01-01</p> <p>The ciliopathies are a group of related inherited diseases characterized by malformations in organ development. The diseases affect multiple organ <span class="hlt">systems</span>, with kidney, skeleton, and brain malformations frequently observed. Research over the last decade has revealed that these diseases are due to defects in <span class="hlt">primary</span> cilia, essential sensory organelles found on most cells in the human body. Here we discuss the genetic and cell biological basis of one of the most severe ciliopathies, Meckel-Gruber syndrome, and explain how <span class="hlt">primary</span> cilia contribute to the development of the affected organ <span class="hlt">systems</span>. PMID:24322779</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/23144196','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/23144196"><span>Central nervous <span class="hlt">system</span> recurrence of <span class="hlt">systemic</span> lymphoma in the era of stem cell transplantation--an International <span class="hlt">Primary</span> Central Nervous <span class="hlt">System</span> Lymphoma Study Group project.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Bromberg, Jacoline E; Doorduijn, Jeanette K; Illerhaus, Gerald; Jahnke, Kristoph; Korfel, Agniezka; Fischer, Lars; Fritsch, Kristina; Kuittinen, Outti; Issa, Samar; van Montfort, Cees; van den Bent, Martin J</p> <p>2013-05-01</p> <p>Autologous stem cell transplantation has greatly improved the prognosis of <span class="hlt">systemic</span> recurrent non-Hodgkin's lymphoma. However, no prospective data are available concerning the feasibility and efficacy of this strategy for <span class="hlt">systemic</span> lymphoma relapsing in the central nervous <span class="hlt">system</span>. We, therefore, we performed an international multicenter retrospective study of patients with a central nervous <span class="hlt">system</span> recurrence of <span class="hlt">systemic</span> lymphoma to assess the outcome of these patients in the era of stem cell transplantation. We collected clinical and treatment data on patients with a first central nervous <span class="hlt">system</span> recurrence of <span class="hlt">systemic</span> lymphoma treated between 2000 and 2010 in one of five centers in four countries. Patient- and treatment-related factors were analyzed and compared descriptively. <span class="hlt">Primary</span> outcome measures were overall survival and percentage of patients transplanted. We identified 92 patients, with a median age of 59 years and a median Eastern Cooperative Oncology Group/World Health Organization performance status of 2, of whom 76% had diffuse large B-cell histology. The majority (79%) of these patients were treated with <span class="hlt">systemic</span> chemotherapy with or without intravenous rituximab. Twenty-seven patients (29%) were transplanted; age and insufficient response to induction chemotherapy were the main reasons for not being transplanted in the remaining 65 patients. The median overall survival was 7 months (95% confidence interval 2.6-11.4), being 8 months (95% confidence interval 3.8-5.2) for patients ≤ 65 years old. The 1-year survival rate was 34.8%; of the 27 transplanted patients 62% survived more than 1 year. The Memorial Sloan Kettering Prognostic Index for <span class="hlt">primary</span> central nervous <span class="hlt">system</span> lymphoma was prognostic for both undergoing transplantation and survival. In conclusion, despite the availability of autologous stem cell transplantation for patients with central nervous <span class="hlt">system</span> progression or relapse of <span class="hlt">systemic</span> lymphoma, prognosis is still poor. Long-term survival</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3891969','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3891969"><span>Intermittency Coding in the <span class="hlt">Primary</span> Olfactory <span class="hlt">System</span>: A Neural Substrate for Olfactory Scene Analysis</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Park, Il Memming; Bobkov, Yuriy V.; Ache, Barry W.</p> <p>2014-01-01</p> <p>The spatial and temporal characteristics of the visual and acoustic sensory input are indispensable attributes for animals to perform scene analysis. In contrast, research in olfaction has focused almost exclusively on how the nervous <span class="hlt">system</span> analyzes the quality and quantity of the sensory signal and largely ignored the spatiotemporal dimension especially in longer time scales. Yet, detailed analyses of the turbulent, intermittent structure of water- and air-borne odor plumes strongly suggest that spatio-temporal information in longer time scales can provide major cues for olfactory scene analysis for animals. We show that a bursting subset of <span class="hlt">primary</span> olfactory receptor neurons (bORNs) in lobster has the unexpected capacity to encode the temporal properties of intermittent odor signals. Each bORN is tuned to a specific range of stimulus intervals, and collectively bORNs can instantaneously encode a wide spectrum of intermittencies. Our theory argues for the existence of a novel peripheral mechanism for encoding the temporal pattern of odor that potentially serves as a neural substrate for olfactory scene analysis. PMID:24431452</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5266020','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5266020"><span><span class="hlt">Primary</span> central nervous <span class="hlt">system</span> ALK-positive anaplastic large cell lymphoma in an adult</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Dong, Xiaoqin; Li, Jun; Huo, Na; Wang, Yan; Wu, Zhao; Lin, Xiaohong; Zhao, Hong</p> <p>2016-01-01</p> <p>Abstract Rationale: Anaplastic large cell lymphoma (ALCL) is an aggressive non-Hodgkin lymphoma. It mostly invades lymph nodes with extranodal involvement observed in the soft tissue, bone, and skin. Patient concerns: We report a 34-year-old Chinese male patient who presented with headache, diplopia, and vomit. Cerebrospinal fluid (CSF) analysis via lumbar puncture showed elevated CSF pressure, elevated CSF protein concentrations, decreased CSF glucose and chloride concentration significantly, and pleocytosis of 68 to 350 × 106/L, in which lymphocytes and monocytes were predominant. These changes could be suggestive of tuberculous (TB) meningitis. Enhanced magnetic resonance imaging of spinal cord delineated multiple enhancing nodules in spinal cord, cauda equina, and cristae membrane, and multiple abnormal enhancing lesions in bilateral lumbar intervertebral foramen. Diagnoses: Spinal dura mater biopsy and paraffin pathology examination revealed anaplastic lymphoma kinase positive ALCL. Interventions: High-dose methotrexate, cytosine arabinoside craniospinal, and radiotherapy. Outcomes: Last follow-up on September 22, 2015 showed no evidence of tumor recurrence and the lower extremity muscle strength recovered to 4/5. Lessons: ALCL of <span class="hlt">primary</span> central nervous <span class="hlt">system</span> is an exceedingly rare tumor, which is usually misdiagnosed as meningitis (especially TB meningitis) according to clinical manifestation and laboratory examination. Thus closely monitoring patient's conditions and timely adjusting therapeutic regimen during treatment are necessary. PMID:27930548</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28140306','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28140306"><span>[Retrospective study of 48 cases of <span class="hlt">primary</span> central nervous <span class="hlt">system</span> lymphoma].</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Alessandro, Lucas; Pastor Rueda, José M; Villalonga, Juan F; Bruno, Verónica A; Carpani, Federico; Blaquier, Juan B; Tognarelli, Sofía; Varela, Francisco J; Muggeri, Alejandro</p> <p>2017-01-01</p> <p><span class="hlt">Primary</span> central nervous <span class="hlt">system</span> lymphoma (PCNSL) is an infrequent form of non-Hodgkin lymphoma restricted to the CNS. More than 90% are type B and mainly affect patients aged 50-70 years. Immunodeficiency is the most important risk factor. The aim of our study was to evaluate the immune status, clinical presentation and findings in complementary studies of PCNSL patients. A retrospective analysis of 48 cases treated in our center between January 1992 and May 2015 was performed. Median age at diagnosis was 61 years (range 25-84); with male predominance (2.1:1). Forty one cases (85%) were immunocompetent patients. Brain MRI findings showed parenchymal involvement in 45 cases (94%), 43% with frontal lobe and 35% basal ganglia, 4% had meningeal involvement and 2% had ophthalmic involvement at diagnosis. Fifty-five percent had restricted signal on diffusion weighted imaging and contrast enhancement was found in 89%. Pyramidal syndrome was the main initial clinical manifestation (56%). There were abnormal findings in 62% of CSF samples, but in only 11.1% positive cytology results were detected. The most frequent type was diffuse large B-cell lymphoma (83%), being B-cell type the most common form between them (96%). In our series PCNSL was more frequent in immunocompetent elderly male subjects. At initial evaluation, clinical manifestations and MRI findings were variable. The initial suspicion of this entity would allow an early diagnosis, avoiding empirical treatments that may confuse or delay diagnosis.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.osti.gov/scitech/servlets/purl/900228','SCIGOV-STC'); return false;" href="http://www.osti.gov/scitech/servlets/purl/900228"><span>Review of Failure Probability Calculations for HFIR <span class="hlt">Primary</span> Coolant <span class="hlt">System</span> Piping</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Simonen, Fredric A.</p> <p>2001-10-31</p> <p>During July 2001, Pacific Northwest National Laboratory was requested by the U.S. Department of Energy, Office of Nuclear Facilities Management, Office of Nuclear Energy, Science and Technology, Germantown, Maryland, to review calculations of piping failure probabilities for the High Flux Test Reactor (HFIR) located at and operated by the Oak Ridge National Laboratory (ORNL). The objective of the failure probability calculations was to estimate the probabilities of large leaks (>1500 gpm) that are of sufficient size to disable the <span class="hlt">primary</span> coolant <span class="hlt">system</span> of HFIR to the extent that there is a potential for core damage. PNNL reviewed the computational methods and the inputs to the calculations along with an evaluation of potential failure mechanisms not explicitly addressed by the ORNL calculations. The review concluded that the calculated failure probabilities even with consideration of uncertainties in the calculations and of other potential failure mechanisms provide a high level of confidence that failure frequencies are less than the stated goal of 10-6 piping failures per year.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27018254','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27018254"><span>Trends in <span class="hlt">primary</span> central nervous <span class="hlt">system</span> lymphoma incidence and survival in the U.S.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Shiels, Meredith S; Pfeiffer, Ruth M; Besson, Caroline; Clarke, Christina A; Morton, Lindsay M; Nogueira, Leticia; Pawlish, Karen; Yanik, Elizabeth L; Suneja, Gita; Engels, Eric A</p> <p>2016-08-01</p> <p>It is suspected that <span class="hlt">primary</span> central nervous <span class="hlt">system</span> lymphoma (PCNSL) rates are increasing among immunocompetent people. We estimated PCNSL trends in incidence and survival among immunocompetent persons by excluding cases among human immunodeficiency virus (HIV)-infected persons and transplant recipients. PCNSL data were derived from 10 Surveillance, Epidemiology and End Results (SEER) cancer registries (1992-2011). HIV-infected cases had reported HIV infection or death due to HIV. Transplant recipient cases were estimated from the Transplant Cancer Match Study. We estimated PCNSL trends overall and among immunocompetent individuals, and survival by HIV status. A total of 4158 PCNSLs were diagnosed (36% HIV-infected; 0·9% transplant recipients). HIV prevalence in PCNSL cases declined from 64·1% (1992-1996) to 12·7% (2007-2011), while the prevalence of transplant recipients remained low. General population PCNSL rates were strongly influenced by immunosuppressed cases, particularly in 20-39 year-old men. Among immunocompetent people, PCNSL rates in men and women aged 65+ years increased significantly (1·7% and 1·6%/year), but remained stable in other age groups. Five-year survival was poor, particularly among HIV-infected cases (9·0%). Among HIV-uninfected cases, 5-year survival increased from 19·1% (1992-1994) to 30·1% (2004-2006). In summary, PCNSL rates have increased among immunocompetent elderly adults, but not in younger individuals. Survival remains poor for both HIV-infected and HIV-uninfected PCNSL patients.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/15886021','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/15886021"><span>Task-relevant modulation of <span class="hlt">primary</span> somatosensory cortex suggests a prefrontal-cortical sensory gating <span class="hlt">system</span>.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Schaefer, Michael; Heinze, Hans-Jochen; Rotte, Michael</p> <p>2005-08-01</p> <p>Increasing evidence suggests that somatosensory information is modulated cortically for task-specific sensory inflow: Several studies report short-term adaptation of representational maps in <span class="hlt">primary</span> somatosensory cortex (SI) due to attention or induced by task-related motor activity such as handwriting. Recently, it has been hypothesized that the frontal or prefrontal cortex may modulate SI. In order to test this hypothesis, we studied the functional organization of SI while subjects performed the Tower of Hanoi task. This task is known to be related to activation of frontal or prefrontal areas. The functional organization of SI while performing the Tower of Hanoi task was compared to the organization of SI during performing the same movements but without the Tower of Hanoi task and with rest. Topography of SI was assessed using neuromagnetic source imaging based on tactile stimulation of the first (D1) and fifth digits (D5). Performing the Tower of Hanoi task was accompanied by plastic changes in SI as indicated by significant shifts in the cortical representations of D1 and D5: They moved further apart during the Tower of Hanoi task compared to the control task containing the same movements but without the cognitive characteristic. Thus, we conclude that SI maps undergo dynamic modulation depending on motor tasks with different cognitive demands. The results suggest that this short-term plasticity may be regulated by a prefrontal-cortical sensory gating <span class="hlt">system</span>.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/6972919','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/6972919"><span>Imbalances of T cell subpopulations in <span class="hlt">primary</span> immunodeficiencies and <span class="hlt">systemic</span> lupus erythematosus.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Pandolfi, F; Quinti, I; Sirianni, M C; Fiorilli, M; Zolla, S; Aiuti, F</p> <p>1981-01-01</p> <p>In the present report we describe a recently proposed technique for the enumeration of T lymphocyte subpopulations. The study was performed on peripheral blood lymphocytes (PBL) of 21 patients with <span class="hlt">primary</span> immunodeficiencies and 10 with <span class="hlt">systemic</span> lupus erythematosus (SLE). With this methodology, sheep rosettes are evaluated before and after preincubation with theophylline. Previous reports have shown that cells rosetting after the preincubation (T-res) contain most of the percentages of the helper activity, whereas sensitive cells (T-sens) exert suppression. T-res and T-sens cells were compared to several clinical and immunological parameters, including the detection of lymphocytes with Fc IgM and IgG receptors. We demonstrated a significant positive correlation between T-res and and EAox IgM cells and between T-sens and EAox IgG cells. In addition, patients with Ig defects demonstrated heterogeneity regarding alterations in the proportions of T-res and T-sens cells. On the contrary, in 8 patients with SLE, there was a markedly reduced proportion of T-sens cells. Variations in the balance of subpopulations were observed after treatment with thymic hormones and levamisole. We may conclude that theophylline rosettes represent an easy technique that can be profitably used in the evaluation of T cell subpopulations in immunological diseases.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/24750231','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/24750231"><span>Intraoperative rapid diagnosis of <span class="hlt">primary</span> central nervous <span class="hlt">system</span> lymphomas: advantages and pitfalls.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Sugita, Yasuo; Terasaki, Mizuhiko; Nakashima, Shinji; Ohshima, Koichi; Morioka, Motohiro; Abe, Hideyuki</p> <p>2014-10-01</p> <p>To study the advantages and pitfalls of intraoperative rapid diagnosis (IRD) of <span class="hlt">primary</span> central nervous <span class="hlt">system</span> lymphomas (PCNSL), pathology reports and frozen sections in our institution were reviewed. We examined 27 cases of PCNSL, one case of anaplastic glioma, and one case of metastatic brain tumor that were diagnosed on neuroimaging. Fifteen cases of intraoperative cytological preparations were also reviewed in a correlative manner. Among the 27 cases initially diagnosed as PCNSL, 18 were also diagnosed as PCNSL by IRD. However, IRD identified four of the 27 cases as gliosis, two as demyelination, one as atypical epithelial cells, one as malignant glioma and anaplastic astrocytoma. In addition, the case identified as metastatic brain tumor on neuroimaging was corrected to a diagnosis of PCNSL based on IRD. The final accuracy of IRD in the present study was 89.6% (26/29). After postoperative definitive diagnosis, two cases of anaplastic astrocytoma and one case of PCNSL by IRD were corrected to PCNSL, anaplastic oligodendroglioma and demyelination, respectively. PCNSL were sometimes histologically indistinguishable from malignant gliomas or demyelinating diseases in the present study, particularly in frozen sections. Notably, all cases for which both intraoperative cytology and frozen section were performed concomitantly were correctly diagnosed in the present study. In particular, lymphoglandular bodies were highly characteristic cytological findings of PCNSL. Both intraoperative cytology and frozen sections should therefore be performed concomitantly when PCNSL are suspected.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2014ChPhL..31b8502X','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2014ChPhL..31b8502X"><span>Sensing Characteristics of Shear-Mode <span class="hlt">Al</span>N Solidly Mounted Resonators with a Silicone Microfluidic <span class="hlt">System</span> in Viscous Media</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Xiong, Juan; Guo, Peng; Sun, Xi-Liang; Wang, Sheng-Fu; Hu, Ming-Zhe; Gu, Hao-Shuang</p> <p>2014-02-01</p> <p><span class="hlt">Al</span>N solidly mounted resonators with silicone microfluidic <span class="hlt">systems</span> vibrating in shear mode are fabricated and characterized. The fabrication process is compatible with integrated circuits and the c-axis tilted <span class="hlt">Al</span>N films are deposited, which allow in-liquid operation through excitation of the shear mode. The silicone microfluidic <span class="hlt">system</span> is mounted on top of the sensor chip to transport the analyses and confine the flow to the active area. The properties of sensor operation in air, deionized water, ethanol, isopropanol, 80% glycol aqueous solution, glycol, and olive oil are characterized. The effects of different viscosities on the resonance frequency shift and Q-factor of the sensor have been discussed. The sensitivity and Q value in glycol of the sensor are 1.52 MHz cm2/μg and around 60, respectively. The results indicate the potential of a highly sensitive microfluidic sensor <span class="hlt">system</span> for the applications in viscous media.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2009JAP...106d4510T','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2009JAP...106d4510T"><span>Influence of Ni silicide phases on effective work function modulation with <span class="hlt">Al</span>-pileup in the Ni fully silicided gate/HfSiON <span class="hlt">system</span></span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Tsuchiya, Yoshinori; Yoshiki, Masahiko; Koga, Junji; Nishiyama, Akira; Koyama, Masato</p> <p>2009-08-01</p> <p>Influences of Ni silicide phases on the effective work function (Φeff) modulation effect with <span class="hlt">Al</span> incorporation has been investigated in the Ni silicide/HfSiON <span class="hlt">systems</span>. We formed metal-insulator-semiconductor capacitors with <span class="hlt">Al</span> incorporated Ni silicide (NiSi, Ni2Si, and Ni3Si) gates on HfSiON by <span class="hlt">Al</span> solid-phase diffusion (<span class="hlt">Al</span>-SPD) process or <span class="hlt">Al</span> ion implantation (I/I) process. In the <span class="hlt">Al</span>-SPD process, <span class="hlt">Al</span> is deposited on Ni silicide gate. In the <span class="hlt">Al</span>-I/I process, <span class="hlt">Al</span> ions were doped in the upper part of Ni silicide layer. In both cases, we performed <span class="hlt">Al</span> drive-in annealing under the condition of 450 °C for 30 min in N2 ambient. It is found that the flat-band voltage (Vfb) values of <span class="hlt">Al</span> incorporated NiSi and Ni2Si gates shift negatively and identical independent of <span class="hlt">Al</span> incorporation processes. A highly concentrated <span class="hlt">Al</span> piled-up layer, which induces Φeff modulation to <span class="hlt">Al</span>-Φeff value, seems to correspond to the Vfb modulation. On the other hand, <span class="hlt">Al</span> incorporation has little influence on Φeff at the Ni3Si/HfSiON interface. We revealed that a lower <span class="hlt">Al</span> diffusion coefficient in Ni3Si phase reduces the <span class="hlt">Al</span> interface density at the Ni3Si/HfSiON interface. In addition, <span class="hlt">Al</span> piled-up layer is inherently unstable at the Ni3Si/HfSiON interface, which is confirmed from the detailed investigation about thermal stability of <span class="hlt">Al</span> piled-up layer by using phase change process from NiSi to Ni3Si phase.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/15669584','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/15669584"><span>Treating asthma by the guidelines: developing a medication management information <span class="hlt">system</span> for use in <span class="hlt">primary</span> care.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Twiggs, Joan E; Fifield, J; Jackson, E; Cushman, R; Apter, A</p> <p>2004-01-01</p> <p>The aim of this study was to develop, implement, and assess an automated asthma medication management information <span class="hlt">system</span> (MMIS) that provides patient-specific evaluative guidance based on 1997 NAEPP clinical consensus guidelines. MMIS was developed and implemented in <span class="hlt">primary</span> care settings within a pediatric asthma disease management program. MMIS infrastructure featured a centralized database with Internet access. MMIS collects detailed patient asthma medication data, evaluates pharmacotherapy relative to practitioner-reported disease severity, symptom control and model of guideline-recommended severity-appropriate medications and produces a patient-specific "curbside consult" feedback report. A <span class="hlt">system</span> algorithm translates actual detailed medication data into actual severity-specific medication-class combinations. A table-driven computer program compares actual medication-class combinations to a guideline-based medication-class combinations model. Methodology determines whether the patient was prescribed a "severity-appropriate" amount or an amount "more" or "less" medication than indicated for patient's reported severity. Feedback messages comment on comparison. Missing data, unrecognized amounts of controller medication or unrecognized medication combinations create error cases. Post hoc review analyzed error cases to determine prevalence of non-guideline medicating practices among these practitioners. Proportion of valid and error cases across two clinical visits before and after post hoc clinical review were measured, as well as proportion of severity-appropriate, out-of-severity and non-guideline medications. MMIS produced a valid feedback report for 83% of patient visits. Missing data accounted for 60% of error cases. Practitioners used severity-appropriate medications for 60% of cases. When non-severity-appropriate medications were used they tended to be "too much" rather than "too little" (22%, 5%), suggesting appropriate use of guideline-recommended "step</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25031012','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25031012"><span>MGMT promoter methylation and correlation with protein expression in <span class="hlt">primary</span> central nervous <span class="hlt">system</span> lymphoma.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Toffolatti, L; Scquizzato, E; Cavallin, S; Canal, F; Scarpa, M; Stefani, P M; Gherlinzoni, F; Dei Tos, A P</p> <p>2014-11-01</p> <p>The O (6)-methylguanine-DNA-methyltransferase (MGMT) gene encodes for a DNA repairing enzyme of which silencing by promoter methylation is involved in brain tumorigenesis. MGMT promoter methylation represents a favorable prognostic factor and has been associated with a better response to alkylating agents in glioma and <span class="hlt">systemic</span> lymphoma. <span class="hlt">Primary</span> central nervous <span class="hlt">system</span> lymphoma (PCNSL) is a rare and aggressive extranodal malignant lymphoma. The current standard of care, based on high-dose methotrexate chemotherapy, has improved prognosis but outcome remains poor for a majority of patients. Therapeutic progress in this field is conditioned by limited biological and molecular knowledge about the disease. Temozolomide has recently emerged as an alternative option for PCNSL treatment. We aimed to analyze the MGMT gene methylation status in a series of 24 PCNSLs, to investigate the relationship between methylation status of the gene and immunohistochemical expression of MGMT protein and to evaluate the possible prognostic significance of these biomarkers. Our results confirm that methylation of the MGMT gene and loss of MGMT protein are frequent events in these lymphomas (54 % of our cases) and suggest that they are gender and age related. MGMT methylation showed high correlation with loss of protein expression (concordance correlation coefficient = -0.49; Fisher exact test: p < 0.01), different from what has been observed in other brain tumors. In the subgroup of ten patients who received high dose chemotherapy, the presence of methylated MGMT promoter (n = 4), seems to be associated with a prolonged overall survival (>60 months in three of four patients). The prognostic significance of these molecular markers in PCNSL needs to be further studied in groups of patients treated in a homogeneous way.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/24967356','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/24967356"><span>Cell communication in a coculture <span class="hlt">system</span> consisting of outgrowth endothelial cells and <span class="hlt">primary</span> osteoblasts.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Herzog, David Paul Eric; Dohle, Eva; Bischoff, Iris; Kirkpatrick, Charles James</p> <p>2014-01-01</p> <p>Bone tissue is a highly vascularized and dynamic <span class="hlt">system</span> with a complex construction. In order to develop a construct for implant purposes in bone tissue engineering, a proper understanding of the complex dependencies between different cells and cell types would provide further insight into the highly regulated processes during bone repair, namely, angiogenesis and osteogenesis, and might result in sufficiently equipped constructs to be beneficial to patients and thereby accomplish their task. This study is based on an in vitro coculture model consisting of outgrowth endothelial cells and <span class="hlt">primary</span> osteoblasts and is currently being used in different studies of bone repair processes with special regard to angiogenesis and osteogenesis. Coculture <span class="hlt">systems</span> of OECs and pOBs positively influence the angiogenic potential of endothelial cells by inducing the formation of angiogenic structures in long-term cultures. Although many studies have focused on cell communication, there are still numerous aspects which remain poorly understood. Therefore, the aim of this study is to investigate certain growth factors and cell communication molecules that are important during bone repair processes. Selected growth factors like VEGF, angiopoietins, BMPs, and IGFs were investigated during angiogenesis and osteogenesis and their expression in the cultures was observed and compared after one and four weeks of cultivation. In addition, to gain a better understanding on the origin of different growth factors, both direct and indirect coculture strategies were employed. Another important focus of this study was to investigate the role of "gap junctions," small protein pores which connect adjacent cells. With these bridges cells are able to exchange signal molecules, growth factors, and other important mediators. It could be shown that connexins, the gap junction proteins, were located around cell nuclei, where they await their transport to the cell membrane. In addition, areas in which two</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016SuScT..29g5001L','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016SuScT..29g5001L"><span>Phase formation and superconducting properties of mechanically alloyed Nb3(<span class="hlt">Al</span>1-x Ge x ) <span class="hlt">system</span></span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Li, Pingyuan; Chen, Yongliang; Xu, Liyuan; Zhang, Yun; Pan, Xifeng; Yan, Guo; Zhang, Yong; Cheng, C. H.; Feng, Yong; Zhao, Yong</p> <p>2016-07-01</p> <p>Mechanically alloyed Nb3(<span class="hlt">Al</span>1-x Ge x ) compounds with nominal composition x = 0%, 10%, 15%, 20%, 25% and 30% were synthesized using high-energy ball milling. The effects of Ge content and sintering temperature on the formation of the Nb3<span class="hlt">Al</span> superconducting phase at a relatively low temperature without the extremely high-temperature rapid heating, quenching and transformation process were studied. The results revealed that Ge doping in Nb3<span class="hlt">Al</span> improved the formation of the A15 phase at low temperatures, enhanced the superconducting transition temperature (T c), and refined the grain structure, thus improving the overall superconducting properties. The pinning behavior was also studied for the optimized sample.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/pages/biblio/1221954-simulation-atomic-diffusion-fcc-nial-system-kinetic-monte-carlo-study','SCIGOV-DOEP'); return false;" href="https://www.osti.gov/pages/biblio/1221954-simulation-atomic-diffusion-fcc-nial-system-kinetic-monte-carlo-study"><span>Simulation of atomic diffusion in the Fcc Ni<span class="hlt">Al</span> <span class="hlt">system</span>: A kinetic Monte Carlo study</span></a></p> <p><a target="_blank" href="http://www.osti.gov/pages">DOE PAGES</a></p> <p>Alfonso, Dominic R.; Tafen, De Nyago</p> <p>2015-04-28</p> <p>The atomic diffusion in fcc Ni<span class="hlt">Al</span> binary alloys was studied by kinetic Monte Carlo simulation. The environment dependent hopping barriers were computed using a pair interaction model whose parameters were fitted to relevant data derived from electronic structure calculations. Long time diffusivities were calculated and the effect of composition change on the tracer diffusion coefficients was analyzed. These results indicate that this variation has noticeable impact on the atomic diffusivities. A reduction in the mobility of both Ni and <span class="hlt">Al</span> is demonstrated with increasing <span class="hlt">Al</span> content. As a result, examination of the pair interaction between atoms was carried out formore » the purpose of understanding the predicted trends.« less</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_19");'>19</a></li> <li><a href="#" onclick='return showDiv("page_20");'>20</a></li> <li class="active"><span>21</span></li> <li><a href="#" onclick='return showDiv("page_22");'>22</a></li> <li><a href="#" onclick='return showDiv("page_23");'>23</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_21 --> <div id="page_22" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_20");'>20</a></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li class="active"><span>22</span></li> <li><a href="#" onclick='return showDiv("page_23");'>23</a></li> <li><a href="#" onclick='return showDiv("page_24");'>24</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="421"> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2011RJPCA..85.1495L','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2011RJPCA..85.1495L"><span>Activities of the components in a spinel solid solution of the Fe-<span class="hlt">Al</span>-O <span class="hlt">system</span></span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Lykasov, A. A.; Kimyashev, A. A.</p> <p>2011-09-01</p> <p>The conditions of the equilibrium between the Fe3O4-Fe<span class="hlt">Al</span>2O4 solution and wustite are determined by measuring the EMF of galvanic cells containing a solid electrolyte, and the activities of the components in the Fe3O4-Fe<span class="hlt">Al</span>2O4 solution are calculated by treating the results of the experiment on the equilibrium between the spinel solution and wustite. Their properties are found to be different from those of ideal solutions at temperatures of 1000-1300 K. A significant positive deviation from the Raoult's law is believed to indicate the tendency of the solution to decompose. The experimental data are treated in terms of the theory of regular solutions, assuming the energy of mixing to be a function of temperature only. The critical temperature of decomposition for the Fe3O4-Fe<span class="hlt">Al</span>2O4 solution is found to be 1084 K.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=20050168081&hterms=Copper&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D70%26Ntt%3DCopper','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=20050168081&hterms=Copper&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D70%26Ntt%3DCopper"><span>Blanch Resistant and Thermal Barrier Ni<span class="hlt">Al</span> Coating <span class="hlt">Systems</span> for Advanced Copper Alloys</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Raj, Sai V. (Inventor)</p> <p>2005-01-01</p> <p>A method of forming an environmental resistant thermal barrier coating on a copper alloy is disclosed. The steps include cleansing a surface of a copper alloy, depositing a bond coat on the cleansed surface of the copper alloy, depositing a Ni<span class="hlt">Al</span> top coat on the bond coat and consolidating the bond coat and the Ni<span class="hlt">Al</span> top coat to form the thermal barrier coating. The bond coat may be a nickel layer or a layer composed of at least one of copper and chromium-copper alloy and either the bond coat or the Ni<span class="hlt">Al</span> top coat or both may be deposited using a low pressure or vacuum plasma spray.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/scitech/biblio/22261726','SCIGOV-STC'); return false;" href="https://www.osti.gov/scitech/biblio/22261726"><span>Solid state amorphization in the <span class="hlt">Al</span>-Fe binary <span class="hlt">system</span> during high energy milling</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Urban, P. Montes, J. M.; Cintas, J.</p> <p>2013-12-16</p> <p>In the present study, mechanical alloying (MA) of <span class="hlt">Al</span>75Fe25 elemental powders mixture was carried out in argon atmosphere, using a high energy attritor ball mill. The microstructure of the milled products at different stages of milling was characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM) and differential scanning calorimetry (DSC). The results showed that the amorphous phase content increased by increasing the milling time, and after 50 hours the amorphization process became complete. Heating the samples resulted in the crystallization of the synthesized amorphous alloys and the appearance of the equilibrium intermetallic compounds <span class="hlt">Al</span>{sub 5}Fe{sub 2}.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016PhSS...58.1930A','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016PhSS...58.1930A"><span>Study of the KNO3-<span class="hlt">Al</span>2O3 <span class="hlt">system</span> by differential scanning calorimetry</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Amirov, A. M.; Gafurov, M. M.; Rabadanov, K. Sh.</p> <p>2016-09-01</p> <p>The structural and the thermodynamic properties of potassium nitrate KNO3 and its composites with nanosized aluminum oxide <span class="hlt">Al</span>2O3 have been studied by differential scanning calorimetry. It has been found that an amorphous phase forms in composites (1- x)KNO3- x <span class="hlt">Al</span>2O3. The thermal effect corresponding to this phase has been observed at 316°C. It has been found that the phase transition heats of potassium nitrate decreased as the aluminum oxide fraction increased.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/16876842','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/16876842"><span>Interdiffusion of <span class="hlt">Al</span>-Ni <span class="hlt">system</span> enhanced by ultrasonic vibration at ambient temperature.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Li, Mingyu; Ji, Hongjun; Wang, Chunqing; Bang, Han Sur; Bang, Hee Seon</p> <p>2006-12-01</p> <p>At ambient temperature, <span class="hlt">Al</span>-1%Si wire of 25 microm diameter was bonded successfully onto the Au/Ni/Cu pad by ultrasonic wedge bonding technology. Physical process of the bond formation and the interface joining essence were investigated. It is found that the wire was softened by ultrasonic vibration, at the same time, pressure was loaded on the wire and plastic flow was generated in the bonding wire, which promoted the diffusion for Ni into <span class="hlt">Al</span>. Ultrasonic vibration enhanced the interdiffusion that resulted from the inner defects such as dislocations, vacancies, voids and so on, which ascribed to short circuit diffusion.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/18647949','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/18647949"><span>Measuring <span class="hlt">primary</span> care services performance: issues and opportunities from a home care pilot experience in the Tuscan health <span class="hlt">system</span>.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Cinquini, Lino; Vainieri, Milena</p> <p>2008-08-01</p> <p>In recent years in Italy, as in other European countries, profound changes have been introduced in health care both at central and regional levels. Most of them were oriented towards a shift from 'hospital-centred' health care to health care based more on <span class="hlt">primary</span> care services. This transition pursues two objectives: giving more effective responses to citizens' needs and reducing public health expenditure. Changes that involve organizational structure must also be carried out with the introduction of measurement tools that can help in planning and can control the changes. The paper provides the results obtained through the experience of modelling a measurement <span class="hlt">system</span> for <span class="hlt">primary</span> care carried out in 2004 and 2005 by some territorial managers and controllers in the Tuscan Health <span class="hlt">system</span>, and the main issues in measuring <span class="hlt">primary</span> care services emerging from this pilot experience focused on integrated home care services.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://hdl.handle.net/2060/20100040483','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/20100040483"><span>Design and Testing of the <span class="hlt">Primary</span> and Secondary Oxygen Regulators for the Flexible Portable Life Support <span class="hlt">System</span> (FlexPLSS)</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Campbell, Colin; Hepworth, Mark</p> <p>2010-01-01</p> <p>The next generation space suit requires additional capabilities for controlling and adjusting internal pressure compared to that of historical designs. Although the general configuration of the oxygen <span class="hlt">systems</span> for the next generation space suit is similar or derived from the Apollo and Shuttle Extravehicular Mobility Unit (EMU) with <span class="hlt">Primary</span> closed loop life support operation and Secondary sourced open loop life support operations, nearly everything else has evolved with new available technologies. For the case of the <span class="hlt">primary</span> and secondary regulators, the design has gone away from purely mechanical <span class="hlt">systems</span> actuated with pull-cords or "bicycle cables" to electro-mechanical hybrids that provide the best of both worlds with respect to power draw, reliability, and versatility. This paper discusses the development and testing of a Secondary Oxygen Regulator bench-top prototype along with comparisons of operation with the various prototypes for the <span class="hlt">Primary</span> Oxygen Regulator.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/22240231','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/22240231"><span>The FTIR studies of gels and thin films of <span class="hlt">Al</span>2O3-TiO2 and <span class="hlt">Al</span>2O3-TiO2-SiO2 <span class="hlt">systems</span>.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Adamczyk, Anna; Długoń, Elżbieta</p> <p>2012-04-01</p> <p>In this work, samples in form of bulk ones and thin films were obtained using the sol-gel method. The bulk samples were heated at different temperatures (500 °C, 850 °C and 1100 °C) corresponding to the annealing process of coatings, deposited on different substrates by dipping and pulling out samples from the proper sol with the stable speed. Thin films of both <span class="hlt">Al</span>2O3-TiO2 and <span class="hlt">Al</span>2O3-TiO2-SiO2 <span class="hlt">systems</span> were deposited on carbon, steel and titanium substrates in two different ways: as single layers obtained from <span class="hlt">Al</span>2O3 sol, TiO2 sol and <span class="hlt">Al</span>2O3 sol or deposited as mixed coatings from <span class="hlt">Al</span>2O3-TiO2 sol as well as <span class="hlt">Al</span>2O3-TiO2-SiO2 one. All bulk samples were studied by the FTIR spectroscopy and the X-ray diffractometry while thin films were also investigated by the electron microscopy. In the IR spectra of <span class="hlt">Al</span>2O3-TiO2 samples, as well as gels and coatings, bands due to the vibrations of <span class="hlt">Al</span>O bonds of the octahedrally and tetrahedrally coordinated aluminum were observed. The IR spectra of samples of <span class="hlt">Al</span>2O3-TiO2-SiO2 <span class="hlt">system</span> differ from that of <span class="hlt">Al</span>2O3-TiO2 ones in presence of bands assigned to the SiO bond vibrations and in positions of bands due to <span class="hlt">Al</span>O bond vibrations. In all spectra of bulk samples and coatings, the positions of TiO bond vibrations were ascribed basing on the IR spectra of the pure anatase and rutile.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016AcSpA.156...22L','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016AcSpA.156...22L"><span>A simple and rapid method for direct determination of <span class="hlt">Al</span>(III) based on the enhanced resonance Rayleigh scattering of hemin-functionalized graphene-<span class="hlt">Al</span>(III) <span class="hlt">system</span></span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Ling, Yu; Chen, Ling Xiao; Dong, Jiang Xue; Li, Nian Bing; Luo, Hong Qun</p> <p>2016-03-01</p> <p>A novel method for direct determination of <span class="hlt">Al</span>(III) by using hemin-functionalized graphene (H-GO) has been established based on the enhancement of resonance Rayleigh scattering (RRS) intensity. The characteristics of RRS spectra, the optimum reaction conditions, and the reaction mechanism have been investigated. In this experiment, the <span class="hlt">Al</span>(III) would exist in sol-gel <span class="hlt">Al</span>(OH)3 species under the condition of pH 5.9 in aqueous solutions. When H-GO existed in the solution, the sol-gel <span class="hlt">Al</span>(OH)3 would react with H-GO and result in enhancement of RRS intensity, owing to the enhanced hydrophobicity of H-GO surface. Therefore, a simple and rapid sensor for <span class="hlt">Al</span>(III) was developed. The increased intensity of RRS is directly proportional to the concentration of <span class="hlt">Al</span>(III) in the range of 10 nM-6 μM, along with a detection limit of 0.87 nM. Moreover, the sensor has been applied to determination of <span class="hlt">Al</span>(III) concentration in real water and aspirin tablet samples with satisfactory results. Therefore, the proposed method is promising as an effective means for selective and sensitive determination of <span class="hlt">Al</span>(III).</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2012TePhL..38..780R','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2012TePhL..38..780R"><span>Effect of conditions of pulsed electron-beam melting for <span class="hlt">Al</span> (film)/Ti (substrate) <span class="hlt">systems</span> on phase formation and properties of Ti-<span class="hlt">Al</span> surface alloys</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Rotshtein, V. P.; Kolubaeva, Yu. A.; Mei, X.; Markov, A. B.; Naiden, E. P.; Oskomov, K. V.; Pryadko, E. L.; Teresov, A. D.; Shulepov, I. A.; Shulov, V. A.</p> <p>2012-09-01</p> <p>Findings of comparative investigations are presented for phase formation, characteristics of hardening, tribological properties, and oxidation resistance of Ti-<span class="hlt">Al</span> intermetallic surface alloys formed by multiple alternation of deposition of an <span class="hlt">Al</span> film (0.1-1 μm) on a Ti substrate and pulsed liquid-phase mixing of <span class="hlt">Al</span> and Ti by intense low-energy (˜15 keV) electron beams with microsecond (˜3 μs) and submillisecond (100 μs) duration. It is found that microsecond synthesis is effective for formation of γ(Ti<span class="hlt">Al</span>) oxidation-resistant surface alloys. In turn, submillisecond synthesis allows one to form Ti3<span class="hlt">Al</span> surface alloys with enhanced wear resistance.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/24921962','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/24921962"><span>Role of <span class="hlt">primary</span> substrate composition and concentration on attenuation of trace organic chemicals in managed aquifer recharge <span class="hlt">systems</span>.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Alidina, Mazahirali; Li, Dong; Ouf, Mohamed; Drewes, Jörg E</p> <p>2014-11-01</p> <p>This study was undertaken to investigate the role of <span class="hlt">primary</span> substrate composition and concentration on the attenuation of biodegradable emerging trace organic chemicals (TOrCs) in simulated managed aquifer recharge (MAR) <span class="hlt">systems</span>. Four sets of soil columns were established in the laboratory, each receiving synthetic feed solutions comprising different ratios and concentrations of peptone-yeast and humic acid as the <span class="hlt">primary</span> substrate to investigate the effect on removal of six TOrCs (atenolol, caffeine, diclofenac, gemfibrozil, primidone, and trimethoprim). Based on abiotic control experiments, adsorption was not identified as a significant attenuation mechanism for primidone, gemfibrozil and diclofenac. Caffeine, atenolol and trimethoprim displayed initial adsorptive losses, however, adsorption coefficients derived from batch tests confirmed that adsorption was limited and in the long-term experiment, biodegradation was the dominant attenuation process. Within a travel time of 16 h, caffeine - an easily degradable compound exhibited removal exceeding 75% regardless of composition or concentration of the <span class="hlt">primary</span> substrate. Primidone - a poorly degradable compound, showed no removal in any column regardless of the nature of the <span class="hlt">primary</span> substrate. The composition and concentration of the <span class="hlt">primary</span> substrate, however, had an effect on attenuation of moderately degradable TOrCs, such as atenolol, gemfibrozil and diclofenac, with the <span class="hlt">primary</span> substrate composition seeming to have a larger impact on TOrC attenuation than its concentration. When the <span class="hlt">primary</span> substrate consisted mainly of refractory substrate (humic acid), higher removal of the moderately degradable TOrCs was observed. The microbial communities in the columns receiving more refractory carbon, were noted to be more diverse and hence likely able to express a wider range of enzymes, which were more suitable for TOrC transformation. The effect of the <span class="hlt">primary</span> substrate on microbial community composition, diversity</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015AGUFMGC13C1153M','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015AGUFMGC13C1153M"><span>Quantifying Human Appropriated Net <span class="hlt">Primary</span> Productivity (HANPP) in a Ghanaian Cocoa <span class="hlt">System</span></span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Morel, A.; Adu-Bredu, S.; Adu Sasu, M.; Ashley Asare, R.; Boyd, E.; Hirons, M. A.; Malhi, Y.; Mason, J.; Norris, K.; Robinson, E. J. Z.; McDermott, C. L.</p> <p>2015-12-01</p> <p>Ghana is the second largest producer of cocoa (Theobroma cacoa), exporting approximately 18 percent of global volumes. These cocoa farms are predominantly small-scale, ranging in size from 2-4 hectares (ha). Traditionally, the model of cocoa expansion in Ghana relied on clearing new areas of forest and establishing a farm under remnant forest trees. This is increasingly less practical due to few unprotected forest areas remaining and management practices favoring close to full sun cocoa to maximize short-term yields. This study is part of a larger project, ECOLMITS, which is an interdisciplinary, ESPA-funded[1] initiative exploring the ecological limits of ecosystem <span class="hlt">system</span> services (ESS) for alleviating poverty in small-scale agroforestry <span class="hlt">systems</span>. The ecological study plots are situated within and around the Kakum National Forest, a well-protected, moist-evergreen forest of the Lower Guinea Forest region. Net <span class="hlt">primary</span> productivity (NPP) is a measure of the rate at which carbon dioxide (CO2) is incorporated into plant tissues (e.g. canopy, stem and root). For this study, NPP was monitored in situ using methods developed by the Global Environmental Monitoring Network (GEM, http://gem.tropicalforests.ox.ac.uk/). By comparing NPP measured in intact forest and farms, the human appropriated NPP (HANPP) of this <span class="hlt">system</span> can be estimated. The forest measures provide the "potential" NPP of the region, and then the reduction in NPP for farm plots is calculated for both land-cover change (HANPPLUC) and cocoa harvesting (HANPPHARV). The results presented are of the first year of NPP measurements across the cocoa landscape, including measurements from intact forest, logged forest and cocoa farms across a shade gradient and located at varying distances from the forest edge (e.g. 100 m, 500 m, 1 km and 5 km). These measures will have implications for carbon sequestration potential over the region and long-term sustainability of the Ghanaian cocoa sector. [1] Ecosystem Services for</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2000SPIE.4093..397A','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2000SPIE.4093..397A"><span>Design of an interferometric <span class="hlt">system</span> for piston measurements in segmented <span class="hlt">primary</span> mirrors</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Arasa, Josep; Laguarta, Ferran; Pizarro, Carlos; Tomas, Nuria; Pinto, Agusti</p> <p>2000-10-01</p> <p>Recently, telescopes with segmented <span class="hlt">primary</span> mirrors are becoming increasingly popular due to their ability of achieving large apertures without the inconveniences caused by the fabrication and handling of monolithic surfaces with 8m (or over) in diameter. The difference in position of each pair of adjacent segments along the local normal of their interface (called piston hereafter), however, needs to be precisely measured in order to provide a diffraction- limited image. If a <span class="hlt">system</span> yielding the nanometric accuracy required in piston measurements worked in daylight hours, the resultant saving in observation time would be an important advance on a majority of the state-of-the-art piston measurement <span class="hlt">systems</span>. An interferometric piston measurement instrument accomplishing such objectives has been designed starting from the usual Michelson configuration at the CD6 (Terrassa, Spain), and its final test has been carried out in the test workbench of the Instituto de Astrofisica de Canarias (IAC, Canary Islands, Spain). Its optical layout relies on projecting the reference arm of the interferometer onto one of the segments of the pair considered, along the direction of the local normal to the surface while the measurement arm is projected onto the interface which divides the pair of segments considered. The field of view and its illumination are calculated to be equivalent in both segments. The lateral shift of the fringes in both interferograms determines the piston error present. A combination of monochromatic and white light is used, in order to remove the (lambda) /2 phase ambiguities present in piston measurements without losing the required resolution in the measurement. In this paper, the optical design of this interferometric piston measurement instrument will be presented. The particular configuration used in the interferometer, the implementation of an imaging <span class="hlt">system</span> allowing to see both the interface of the segments and the interference fringes, the effect of the</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=tea&pg=2&id=EJ1123604','ERIC'); return false;" href="http://eric.ed.gov/?q=tea&pg=2&id=EJ1123604"><span>Aesthetic Education of <span class="hlt">Primary</span> School Pupils as an Integral Part of the National <span class="hlt">System</span> of Continuous Art Education in Japan</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Kuchai, Tetiana</p> <p>2014-01-01</p> <p>The article examines aesthetic education of <span class="hlt">primary</span> school pupils as an integral part of the national <span class="hlt">system</span> of continuous art education in Japan. One of the most important traditional means of aesthetic education in Japan, according to L. Tsaryova is considered nature. Analysis of the scientific literature by domestic and foreign scientists…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://cfpub.epa.gov/si/si_public_record_report.cfm?dirEntryId=209896&keyword=Yang+AND+B&actType=&TIMSType=+&TIMSSubTypeID=&DEID=&epaNumber=&ntisID=&archiveStatus=Both&ombCat=Any&dateBeginCreated=&dateEndCreated=&dateBeginPublishedPresented=&dateEndPublishedPresented=&dateBeginUpdated=&dateEndUpdated=&dateBeginCompleted=&dateEndCompleted=&personID=&role=Any&journalID=&publisherID=&sortBy=revisionDate&count=50&CFID=78156608&CFTOKEN=81139215','EPA-EIMS'); return false;" href="http://cfpub.epa.gov/si/si_public_record_report.cfm?dirEntryId=209896&keyword=Yang+AND+B&actType=&TIMSType=+&TIMSSubTypeID=&DEID=&epaNumber=&ntisID=&archiveStatus=Both&ombCat=Any&dateBeginCreated=&dateEndCreated=&dateBeginPublishedPresented=&dateEndPublishedPresented=&dateBeginUpdated=&dateEndUpdated=&dateBeginCompleted=&dateEndCompleted=&personID=&role=Any&journalID=&publisherID=&sortBy=revisionDate&count=50&CFID=78156608&CFTOKEN=81139215"><span>Profiling Bioactivity of the ToxCast Chemical Library Using BioMAP <span class="hlt">Primary</span> Human Cell <span class="hlt">Systems</span></span></a></p> <p><a target="_blank" href="http://oaspub.epa.gov/eims/query.page">EPA Science Inventory</a></p> <p></p> <p></p> <p>The complexity of human biology has made prediction of health effects as a consequence of exposure to environmental chemicals especially challenging. Complex cell <span class="hlt">systems</span>, such as the Biologically Multiplexed Activity Profiling (BioMAP) <span class="hlt">primary</span>, human, cell-based disease models, ...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=Circulatory+AND+system&pg=2&id=EJ832124','ERIC'); return false;" href="http://eric.ed.gov/?q=Circulatory+AND+system&pg=2&id=EJ832124"><span>Effect of 5E Instructional Model in Student Success in <span class="hlt">Primary</span> School 6th Year Circulatory <span class="hlt">System</span> Topic</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Cardak, Osman; Dikmenli, Musa; Saritas, Ozge</p> <p>2008-01-01</p> <p>The aim of this study is to research the effect of the 5E instructional model on <span class="hlt">primary</span> (sixth grade) student success during the circulatory <span class="hlt">system</span> unit. This study was conducted with 38 students in two different classes by the same researcher in 2006-2007. One of the classes was assigned as the control group and the other as the experimental…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.dtic.mil/docs/citations/ADA147521','DTIC-ST'); return false;" href="http://www.dtic.mil/docs/citations/ADA147521"><span>Development of Portable Rapid Diagnostic Microbiology <span class="hlt">Systems</span> for Support of <span class="hlt">Primary</span> Health Care Delivery.</span></a></p> <p><a target="_blank" href="https://publicaccess.dtic.mil/psm/api/service/search/search">DTIC Science & Technology</a></p> <p></p> <p>1981-11-01</p> <p>should receive <span class="hlt">primary</span> attention. In the collective opinion of the delegates to the Alma -Ata Con- ference in 1978, sponsored by the World Health...diagnostic challenge of tropical diseases as seen by an epidemiologist. Amer J Trop Med Hyg 28:171, 1979. 3. WHO (Ed): Alma -Ata 1978. <span class="hlt">Primary</span> Health Care...World Health Organization, Geneva. p2. 4. Waddy BB: African epidemic cerebro -spinal, meningitis. J Trop Med Hyg 60:179, 19. 5. Sanborn WR: A portable</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/22220636','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/22220636"><span>Risk stratification in cardiovascular disease <span class="hlt">primary</span> prevention - scoring <span class="hlt">systems</span>, novel markers, and imaging techniques.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Zannad, Faiez; De Backer, Guy; Graham, Ian; Lorenz, Matthias; Mancia, Giuseppe; Morrow, David A; Reiner, Zeljko; Koenig, Wolfgang; Dallongeville, Jean; Macfadyen, Robert J; Ruilope, Luis M; Wilhelmsen, Lars</p> <p>2012-04-01</p> <p>The aim of this paper is to review and discuss current methods of risk stratification for cardiovascular disease (CVD) prevention, emerging biomarkers, and imaging techniques, and their relative merits and limitations. This report is based on discussions that took place among experts in the area during a special CardioVascular Clinical Trialists workshop organized by the European Society of Cardiology Working Group on Cardiovascular Pharmacology and Drug Therapy in September 2009. Classical risk factors such as blood pressure and low-density lipoprotein cholesterol levels remain the cornerstone of risk estimation in <span class="hlt">primary</span> prevention but their use as a guide to management is limited by several factors: (i) thresholds for drug treatment vary with the available evidence for cost-effectiveness and benefit-to-risk ratios; (ii) assessment may be imprecise; (iii) residual risk may remain, even with effective control of dyslipidemia and hypertension. Novel measures include C-reactive protein, lipoprotein-associated phospholipase A(2) , genetic markers, and markers of subclinical organ damage, for which there are varying levels of evidence. High-resolution ultrasound and magnetic resonance imaging to assess carotid atherosclerotic lesions have potential but require further validation, standardization, and proof of clinical usefulness in the general population. In conclusion, classical risk scoring <span class="hlt">systems</span> are available and inexpensive but have a number of limitations. Novel risk markers and imaging techniques may have a place in drug development and clinical trial design. However, their additional value above and beyond classical risk factors has yet to be determined for risk-guided therapy in CVD prevention.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4740786','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4740786"><span>Antiglutamate Receptor Antibodies and Cognitive Impairment in <span class="hlt">Primary</span> Antiphospholipid Syndrome and <span class="hlt">Systemic</span> Lupus Erythematosus</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Gerosa, Maria; Poletti, Barbara; Pregnolato, Francesca; Castellino, Gabriella; Lafronza, Annalisa; Silani, Vincenzo; Riboldi, Piersandro; Meroni, Pier Luigi; Merrill, Joan T.</p> <p>2016-01-01</p> <p><span class="hlt">Systemic</span> lupus erythematosus (SLE) and antiphospholipid syndrome have an increased risk to develop cognitive impairment. A possible role for antiphospholipid antibodies (aPL) and antiglutamate receptor (anti-NMDA) antibodies in the pathogenesis of neurological manifestations of these two conditions, have been suggested. In particular, the role of anti-NMDA antibodies in the pathogenesis of neuropsychiatric SLE is supported by several experimental studies in animal models and by the finding of a correlation between anti-NMDA positivity in cerebrospinal fluid and neurological manifestations of SLE. However, data from the literature are controversial, as several studies have reported a correlation of these antibodies with mild cognitive impairment in SLE, but more recent studies have not confirmed this finding. The synergism between anti-NMDA and other concomitant autoantibodies, such as aPL, can be hypothesized to play a role in inducing the tissue damage and eventually the functional abnormalities. In line with this hypothesis, we have found a high incidence of at least one impaired cognitive domain in a small cohort of patients with <span class="hlt">primary</span> APS (PAPS) and SLE. Interestingly, aPL were associated with low scoring for language ability and attention while anti-NMDA titers and mini-mental state examination scoring were inversely correlated. However, when patients were stratified according to the presence/absence of aPL, the correlation was confirmed in aPL positive patients only. Should those findings be confirmed, the etiology of the prevalent defects found in PAPS patients as well as the synergism between aPL and anti-NMDA antibodies would need to be explored. PMID:26870034</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/24420722','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/24420722"><span>Distinct antibody profile: a clue to <span class="hlt">primary</span> antiphospholipid syndrome evolving into <span class="hlt">systemic</span> lupus erythematosus?</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Freire, Paula Vieira; Watanabe, Elisa; dos Santos, Nelita Rocha; Bueno, Cleonice; Bonfá, Eloísa; de Carvalho, Jozélio Freire</p> <p>2014-03-01</p> <p>We have performed a retrospective study to determine if patients with antiphospholipid syndrome that developed <span class="hlt">systemic</span> lupus erythematosus (APS/SLE) had distinct clinical and/or serological features. All 80 <span class="hlt">primary</span> APS (PAPS) patients followed up at our APS unit were included in the study and divided into two groups: 14 APS/SLE and 66 PAPS. Prior or at onset of lupus manifestations, six patients were uniformly negative for lupus and Sjögren autoantibodies, and the other eight patients had persistent positive. In the first year after diagnosis of SLE, three patients remained with negative antibodies, the other seven patients maintained the same antibodies, and four patients developed other antibodies. APS/SLE group had a significant lower mean age at PAPS diagnosis (26.0 ± 8.0 vs. 34.2 ± 11.9 years, p = 0.03) and a longer disease duration (14.0 ± 7.0 vs. 6.0 ± 5.0 years, p < 0.0001). The mean time for PAPS to develop SLE was 5.2 ± 4.3 years. The typical clinical and laboratorial findings of APS did not discriminate both groups of patients. At lupus onset, antinuclear antibodies were more frequently observed in those who evolved to SLE (100 vs. 51.5%, p = 0.0005). Anti-double-stranded DNA (dsDNA), anti-ribosomal P, anti-Ro/SS-A, anti-La/SS-B, and anti-U1RNP antibodies were exclusively found in the APS/SLE patients, whereas anti-Smith (Sm) antibodies were not detected in both groups. The detection of a distinct subgroup of lupus-associated autoantibody in PAPS patients seems to be a hint to overt SLE disease, particularly in those patients with young age at diagnosis.</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_20");'>20</a></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li class="active"><span>22</span></li> <li><a href="#" onclick='return showDiv("page_23");'>23</a></li> <li><a href="#" onclick='return showDiv("page_24");'>24</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_22 --> <div id="page_23" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li><a href="#" onclick='return showDiv("page_22");'>22</a></li> <li class="active"><span>23</span></li> <li><a href="#" onclick='return showDiv("page_24");'>24</a></li> <li><a href="#" onclick='return showDiv("page_25");'>25</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="441"> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/15567554','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/15567554"><span><span class="hlt">Primary</span> central nervous <span class="hlt">system</span> lymphoma report of 32 cases and review of the literature.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Dubuisson, Annie; Kaschten, Bruno; Lénelle, Jacques; Martin, Didier; Robe, Pierre; Fassotte, Marie-France; Rutten, Isabelle; Deprez, Manuel; Stevenaert, Achille</p> <p>2004-12-01</p> <p>We retrospectively analyzed 32 cases of <span class="hlt">primary</span> central nervous <span class="hlt">system</span> lymphoma (PCNSL). Five cases were diagnosed in the period 1987-1994, for 27 cases in the period 1995-2002. There were 17 men and 15 women whose median age was 69 years. Three patients were immunodeficient. The commonest symptoms were focal deficit (16 patients) and cognitive/behaviour disturbances (14 patients). Radiologically, a total of 47 contrast-enhancing lesions were observed in 32 patients; 18 patients had deep-seated lesions. All but two patients underwent histological diagnosis following craniotomy (11 patients) and/or stereotaxic biopsy (22 patients); diagnosis was obtained on CSF cytology in one patient with a third ventricle tumour. In the last patient, the diagnosis was based on the finding of marked tumour shrinkage under corticotherapy, despite two negative histological examinations. Treatment included surgical resection (10 patients), chemotherapy (25 patients) and/or radiotherapy (12 patients). According to the therapeutic recommendations of the GELA (Groupe d'Etude des Lymphomes de l'Adulte), 19 patients received at least two courses of high-dose methotrexate; intrathecal chemotherapy was used in 20 patients with methotrexate and/or cytosine arabinoside. Radiation therapy consisted of whole brain irradiation followed by a boost on tumour site. Nine patients received a combined treatment of chemotherapy and radiotherapy. Twelve patients showed rapid progression to death. At the time of last contact, 28/32 patients (88%) had died, all from PCNSL disease or from complications due to its treatment. The median survival time was 13.9 months. We conclude that PCNSL is an increasingly frequent tumour. The diagnosis is obtained by stereotactic biopsy in the majority of cases. The prognosis appears dismal despite an intensive multidisciplinary therapeutic approach.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25132046','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25132046"><span>Analysis of genetic mutations in Chinese patients with <span class="hlt">systemic</span> <span class="hlt">primary</span> carnitine deficiency.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Han, Lianshu; Wang, Fei; Wang, Yu; Ye, Jun; Qiu, Wenjuan; Zhang, Huiwen; Gao, Xiaolan; Gong, Zhuwen; Gu, Xuefan</p> <p>2014-10-01</p> <p><span class="hlt">Systemic</span> <span class="hlt">primary</span> carnitine deficiency (CDSP) is caused by mutations in SLC22A5 gene, which encodes organic cation transporter 2(OCTN2). CDSP leads to skeletal or cardiac myopathy and hepatic encephalopathy. The present study aimed to identify SLC22A5 gene mutations and analyze the potential relationship between genotype and clinical symptoms in 20 Chinese patients with CDSP. The complete coding region of the SLC22A5 gene including intron-exon boundaries were amplified and sequenced in all patients. Eighteen different mutations were found; of which, nine were novel. The mutations clustering in exons 1 and 4 accounted for 66.7% of all mutant alleles (26/39). The c.760C>T (p. R254X) was the most frequent mutation (25.6%, 10/39), suggesting it as an ethnic founder mutation. The relationship between genotype and phenotype was investigated in patients carrying the R254X mutation. Homozygous patients with R254X were late-onset cases who presented with dilated cardiomyopathy and muscle weakness after 1 year of age. Compound heterozygous patients carrying R254X, combined with other missense mutations occurred in very specific positions, dramatically altered OCTN2 protein function. Based on the analysis of case studies, a clear relationship between free carnitine (C0) level in plasma and OCTN2 genotype was not found in the present work, however, the low plasma C0 level could not indicate disease severity or genotype. Further functional studies with a large sample size are required to understand the relationship between R254X mutation and CDSP.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3128023','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3128023"><span><span class="hlt">Primary</span> care utilisation patterns among an urban immigrant population in the Spanish National Health <span class="hlt">System</span></span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p></p> <p>2011-01-01</p> <p>Background There is evidence suggesting that the use of health services is lower among immigrants after adjusting for age and sex. This study takes a step forward to compare <span class="hlt">primary</span> care (PC) utilisation patterns between immigrants and the native population with regard to their morbidity burden. Methods This retrospective, observational study looked at 69,067 individuals representing the entire population assigned to three urban PC centres in the city of Zaragoza (Aragon, Spain). Poisson models were applied to determine the number of annual PC consultations per individual based on immigration status. All models were first adjusted for age and sex and then for age, sex and case mix (ACG <span class="hlt">System</span>®). Results The age and sex adjusted mean number of total annual consultations was lower among the immigrant population (children: IRR = 0.79, p < 0.05; adults: IRR = 0.73, p < 0.05). After adjusting for morbidity burden, this difference decreased among children (IRR = 0.94, p < 0.05) and disappeared among adults (IRR = 1.00). Further analysis considering the PC health service and type of visit revealed higher usage of routine diagnostic tests among immigrant children (IRR = 1.77, p < 0.05) and a higher usage of emergency services among the immigrant adult population (IRR = 1.2, p < 0.05) after adjusting for age, sex and case mix. Conclusions Although immigrants make lower use of PC services than the native population after adjusting the consultation rate for age and sex, these differences decrease significantly when considering their morbidity burden. These results reinforce the 'healthy migration effect' and discount the existence of differences in PC utilisation patterns between the immigrant and native populations in Spain. PMID:21645335</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017MSHT...58..527A','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017MSHT...58..527A"><span>Effect of Annealing on the Electrical Resistivity and Strengthening of Low-Alloy Alloys of the <span class="hlt">Al</span> - Zr - Si <span class="hlt">System</span></span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Alabin, A. N.; Belov, N. A.; Korotkova, N. O.; Samoshinal, M. E.</p> <p>2017-01-01</p> <p>The effect of annealing at up to 550°C on the electrical resistivity ρ and HB hardness of low-alloy alloys of the <span class="hlt">Al</span> - Zr - Si <span class="hlt">system</span> containing up to 0.3% Zr and 0.3% Si is studied. The Thermo-Calc software is used to analyze the phase composition of the <span class="hlt">system</span>. The computed and experimental data are used to determine the lower and upper limits for heating of cast preforms from <span class="hlt">Al</span> - Zr alloys (shaped castings and ingots). It is shown that heating below 400°C and above 450°C is not expedient, because it increases the duration of the annealing in the former case and lowers the hardening effect due to coarsening of the Zr-containing particles in the latter case.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/scitech/biblio/22051137','SCIGOV-STC'); return false;" href="https://www.osti.gov/scitech/biblio/22051137"><span>High rate reactive magnetron sputter deposition of <span class="hlt">Al</span>-doped ZnO with unipolar pulsing and impedance control <span class="hlt">system</span></span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Nishi, Yasutaka; Hirohata, Kento; Tsukamoto, Naoki; Sato, Yasushi; Oka, Nobuto; Shigesato, Yuzo</p> <p>2010-07-15</p> <p><span class="hlt">Al</span>-doped ZnO (AZO) films were deposited on quartz glass substrates, unheated and heated to 200 deg. C, using reactive sputtering with a special feedback <span class="hlt">system</span> of discharge impedance combined with midfrequency pulsing. A planar Zn-<span class="hlt">Al</span> alloy target was connected to the switching unit, which was operated in a unipolar pulse mode. The oxidation of the target surface was precisely controlled by a feedback <span class="hlt">system</span> for the entire O{sub 2} flow ratio including ''the transition region''. The deposition rate was about 10-20 times higher than that for films deposited by conventional sputtering using an oxide target. A deposition rate of AZO films of 390 nm/min with a resistivity of 3.8x10{sup -4} {Omega} cm and a transmittance in the visible region of 85% was obtained when the films were deposited on glass substrates heated to 200 deg. C with a discharge power of 4 kW.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.alsa.org/2015-non-responsive-pages/about-als/diagnosing-als.html','NIH-MEDLINEPLUS'); return false;" href="http://www.alsa.org/2015-non-responsive-pages/about-als/diagnosing-als.html"><span>Diagnosing <span class="hlt">ALS</span></span></a></p> <p><a target="_blank" href="http://medlineplus.gov/">MedlinePlus</a></p> <p></p> <p></p> <p>... that a person diagnosed with <span class="hlt">ALS</span> seek a second opinion from an <span class="hlt">ALS</span> "expert" - someone who diagnoses and treats many <span class="hlt">ALS</span> patients and has training in this medical specialty. The <span class="hlt">ALS</span> Association maintains a list of recognized experts in the field of <span class="hlt">ALS</span>. See <span class="hlt">ALS</span> Association Certified Centers of ...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.dtic.mil/docs/citations/ADA630952','DTIC-ST'); return false;" href="http://www.dtic.mil/docs/citations/ADA630952"><span>Kinetic Metallization. Repair of IVD <span class="hlt">Al</span> Coatings and Mg Alloys Aircraft Components Using Portable Kinetic Metallization <span class="hlt">Systems</span></span></a></p> <p><a target="_blank" href="https://publicaccess.dtic.mil/psm/api/service/search/search">DTIC Science & Technology</a></p> <p></p> <p>2008-02-27</p> <p>person shall be subject to a penalty for failing to comply with a collection of information if it does not display a currently valid OMB control number...aircraft carriers & depots Environmentally sustainable Meets Navy JTP-2003 Portable <span class="hlt">system</span> & Handheld spray gun Robotic deployment for OEM Applications...Problem - Field & Depot Repair of Damaged IVD-<span class="hlt">Al</span> & Mg Alloys NADEP Facilities PEO(T) F/A-18, EA-18G PMA -271 E-6B</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/scitech/biblio/69689','SCIGOV-STC'); return false;" href="https://www.osti.gov/scitech/biblio/69689"><span>Flow strength and size effect of an <span class="hlt">Al</span>-Si-Mg composite model <span class="hlt">system</span> under multiaxial loadings</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Zhu, H.T.; Zbib, H.M.; Khraisheh, M.K.</p> <p>1995-06-01</p> <p>In the present work, using an <span class="hlt">Al</span>-Si-Mg composite model <span class="hlt">system</span>, a series of experiments were conducted to further investigate the effect of microstructural parameters on the flow strength of particulate reinforced MMCs. In addition to the simple tension and torsion tests, biaxial tension-torsion tests were performed to obtain the yield surface, showing the isotropic nature of plastic deformation in these materials. Experimental results are also compared with the prediction of a recently developed theoretical model.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5087231','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5087231"><span><span class="hlt">Primary</span> localized cutaneous amyloidosis with lichen and poikiloderma-like lesions and an excellent response to <span class="hlt">systemic</span> acitretin*</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>MA, Han; Su, Xiangyang; Zhu, Guoxing; Yin, Songchao; Lu, Chun; Lai, Wei</p> <p>2016-01-01</p> <p><span class="hlt">Primary</span> localized cutaneous amyloidosis is a skin-limited amyloidosis that does not involve internal organs. It is clinically subclassified into 3 general categories and some rare variants. However, there is considerable overlap within the classification. Though there are a variety of therapeutic measures, the treatment is often unsatisfactory, particularly when the disease is severe and extensive. We describe a rare case of <span class="hlt">primary</span> localized cutaneous amyloidosis with lichen and poikiloderma-like lesions that showed an excellent response to <span class="hlt">systemic</span> acitretin. PMID:27828646</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26334755','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26334755"><span><span class="hlt">Primary</span> peripheral T-cell lymphoma, not otherwise specified, of the central nervous <span class="hlt">system</span> in a child.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Momota, Hiroyuki; Kato, Seiichi; Fujii, Masazumi; Tsujiuchi, Takashi; Takahashi, Yoshiyuki; Kojima, Seiji; Wakabayashi, Toshihiko</p> <p>2015-10-01</p> <p><span class="hlt">Primary</span> peripheral T-cell lymphoma, not otherwise specified (PTCL-NOS), is a rare disease that infrequently involves the central nervous <span class="hlt">system</span> (CNS), and it is even rarer in pediatric patients. Here, we report of a 13-year-old male with <span class="hlt">primary</span> CNS PTCL-NOS who exhibited a malignant clinical course with recurrence after radiochemotherapy followed by bone marrow transplantation; he died 43 months after diagnosis. Pathology revealed the proliferation of cytotoxic T-cells and clonal T-cell receptor gene rearrangements. Although the optimal therapy for PTCL remains controversial, intensive radiochemotherapy may be required for some patients.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=19810054114&hterms=Free+energy&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D30%26Ntt%3DFree%2Benergy','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=19810054114&hterms=Free+energy&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D30%26Ntt%3DFree%2Benergy"><span>The MgO-<span class="hlt">Al</span>2O3-SiO2 <span class="hlt">system</span> - Free energy of pyrope and <span class="hlt">Al</span>2O3-enstatite. [in earth mantle formation</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Saxena, S. K.</p> <p>1981-01-01</p> <p>The model of fictive ideal components is used to determine Gibbs free energies of formation of pyrope and <span class="hlt">Al</span>2O3-enstatite from the experimental data on coexisting garnet and orthopyroxene and orthopyroxene and spinel in the temperature range 1200-1600 K. It is noted that <span class="hlt">Al</span>2O3 forms an ideal solution with MgSiO3. These thermochemical data are found to be consistent with the <span class="hlt">Al</span>2O3 isopleths that could be drawn using most recent experimental data and with the reversed experimental data on the garnet-spinel field boundary.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/scitech/biblio/21208697','SCIGOV-STC'); return false;" href="https://www.osti.gov/scitech/biblio/21208697"><span>Synthesis of Waste Form in the Gd-Fe-<span class="hlt">Al</span>-Ni-Mn-Cr-O <span class="hlt">System</span></span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Chae, S.C.; Jang, Y.N.; Bae, I.K.; Ryu, K.W.</p> <p>2006-07-01</p> <p>Poly-phase waste form which was the mixture of Gd{sub 3}Fe{sub 2}<span class="hlt">Al</span>{sub 3}O{sub 12} and (Ni{sub x}Mn{sub 1-x})(Fe{sub y}Cr{sub 1-y}){sub 2}O{sub 4} was synthesized. Also, we are intended to examine phase relation and physicochemical properties of coexisted phases in the compositions and to confirm accommodation relation of elements and phases. Two types of phase series were observed: Garnet-perovskite-spinel and Garnet-spinel. The compositions of garnets and spinels were nonstoichiometric, and especially, this poly-phase ceramics may be in a good waste form. The excessive Gd in garnets indicated the immobilization of higher content of actinides. The nonstoichiometric compositions of garnet and spinel were attributed to the formation of perovskite in that perovskite contained Gd, Fe and <span class="hlt">Al</span> from garnet and Cr from spinel. (authors)</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25697116','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25697116"><span>Could astrocytes be the <span class="hlt">primary</span> target of an offending agent causing the <span class="hlt">primary</span> degenerative diseases of the human central nervous <span class="hlt">system</span>? A hypothesis.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Sica, Roberto E</p> <p>2015-05-01</p> <p>Most of the named <span class="hlt">primary</span> degenerative diseases of the human central nervous <span class="hlt">system</span> have been attributed to a direct, <span class="hlt">primary</span> damage of some particular population of neurons. Within the spectrum of these illnesses there are disorders like amyotrophic lateral sclerosis, fronto-temporal dementia, Alzheimer's dementia, Parkinson's disease, Huntington's dementia and cerebellar ataxias affecting exclusively the human species. In the last years it has been shown that non-neural cells, mainly astrocytes, have a crucial role in the starting and development of these diseases. We suggest that the causative agent of these illnesses gets home first within the astrocytes, rather than the neurons, making them sick by modifying the structure of some proteins; from these cells the abnormal process would start a trip to other astrocytes having the same genetic, metabolic, structural and functional profiles that the originally affected astrocytes have, going through the gap junctions which connect that particular population devoted to a particular set of neurons. This appears to be a likely hypothesis because the astrocytes related to a defined population of neurons have their own, private properties and characteristics needed to support one particular set of neurons performing a defined function, making them a different and unique population, a fact which would limit the spreading of the disease to those astrocytes, sparing other astrocyte populations which do not share those characteristics. If this were the mechanism underlying these illnesses, the neurons, which their health depends on those astrocytes, would be deprived of their patronage and would start all the changes that characterizes a programmed cell death, and the clinical manifestations of a defined pathology would consequently appear.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5312106','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5312106"><span>Innovative approaches to establish and characterize <span class="hlt">primary</span> cultures: an ex vivo 3D <span class="hlt">system</span> and the zebrafish model</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Liverani, Chiara; La Manna, Federico; Groenewoud, Arwin; Mercatali, Laura; Van Der Pluijm, Gabri; Pieri, Federica; Cavaliere, Davide; De Vita, Alessandro; Spadazzi, Chiara; Miserocchi, Giacomo; Bongiovanni, Alberto; Recine, Federica; Riva, Nada; Amadori, Dino; Tasciotti, Ennio; Snaar-Jagalska, Ewa</p> <p>2017-01-01</p> <p>ABSTRACT Patient-derived specimens are an invaluable resource to investigate tumor biology. However, in vivo studies on <span class="hlt">primary</span> cultures are often limited by the small amount of material available, while conventional in vitro <span class="hlt">systems</span> might alter the features and behavior that characterize cancer cells. We present our data obtained on <span class="hlt">primary</span> dedifferentiated liposarcoma cells cultured in a 3D scaffold-based <span class="hlt">system</span> and injected into a zebrafish model. <span class="hlt">Primary</span> cells were characterized in vitro for their morphological features, sensitivity to drugs and biomarker expression, and in vivo for their engraftment and invasiveness abilities. The 3D culture showed a higher enrichment in cancer cells than the standard monolayer culture and a better preservation of liposarcoma-associated markers. We also successfully grafted <span class="hlt">primary</span> cells into zebrafish, showing their local migratory and invasive abilities. Our work provides proof of concept of the ability of 3D cultures to maintain the original phenotype of ex vivo cells, and highlights the potential of the zebrafish model to provide a versatile in vivo <span class="hlt">system</span> for studies with limited biological material. Such models could be used in translational research studies for biomolecular analyses, drug screenings and tumor aggressiveness assays. PMID:27895047</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/1999PhDT.......256M','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/1999PhDT.......256M"><span>Phase equilibria and transformations in the Ti-<span class="hlt">Al</span>-Nb <span class="hlt">system</span></span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Mishurda, Joseph Constantine</p> <p></p> <p>The phase equilibria and transformations in the Nb-Ti-<span class="hlt">Al</span> <span class="hlt">system</span> in the vicinity of the Sigma phase field have been examined with respect to the Liquidus Surface (Phase 1), the Phase Equilibria and Equilibrium Transformations (Phase II), and the Phase Transformations, Mechanisms and Kinetics (Phase III). Eight alloy compositions were produced by arc melting. The alloys were characterized by differential thermal analysis, metallography, X-ray diffraction, scanning electron microscopy (BSEI), electron probe microanalysis and transmission electron microscopy. The liquidus examination shed new light on previous microstructural interpretations, opening up new possibilities for microstructural development and control of multiphase alloys. Differential thermal analysis has identified the existence of a beta to sigma + gamma transformation in an alloy where it was not previously thought to exist. The results differed from the calculated diagram by higher titanium solubility in the sigma and delta phases than predicted at lower temperatures and a lower solubility of alpha2 and gamma. The high temperature betao transforms to gamma + sigma in a eutectoid fashion resulting in a desirable lamellar structure of sigma and gamma. The existence of a new body centered tetragonal crystal structure ao = 5.11A and co 28.12A with a point group symmetry of P4/mmm, at 700°C was discovered. A plethel section was found for the sigma + beta two phase alloys. A betao + O + sigma three phase field passes through the alloys between 981 and 1000°C. The plethel section at the transformation has an eutectoid characteristic, however, the nature of the transformation changes to a peritectoid. At temperatures below 970°C, the first transformation to occur is the decomposition of the metastable betao phase to an intermediate metastable phase O'. Reasonable values for Q were obtained, applicable to the diffusion limited region of the TTT-curve. The microstructure evolution of the sigma + beta</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.osti.gov/scitech/biblio/7209323','DOE-PATENT-XML'); return false;" href="http://www.osti.gov/scitech/biblio/7209323"><span>High-transition-temperature superconductors in the Nb-<span class="hlt">Al</span>-Ge <span class="hlt">system</span></span></a></p> <p><a target="_blank" href="http://www.osti.gov/doepatents">DOEpatents</a></p> <p>Giorgi, A.L.; Szklarz, E.G.</p> <p>1972-09-26</p> <p>The patent describes superconducting materials of the nominal composition Nb(x)<span class="hlt">Al</span>(y)Ge(l-y), where x is in the range of 1.9 to 2.8 and y is in the range of 0.5 to 0.9, having transition temperatures in the 19 -20K. range which are readily produced by annealing arc-melted compositions, or cold-pressed, heat-treated compositions at moderate temperatures for reasonably long times (about 50 hours).</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016PhRvB..94i4111G','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016PhRvB..94i4111G"><span>Phase and structural stability in Ni-<span class="hlt">Al</span> <span class="hlt">systems</span> from first principles</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Goiri, Jon Gabriel; Van der Ven, Anton</p> <p>2016-09-01</p> <p>We report on a comprehensive first-principles study of phase stability in the Ni-<span class="hlt">Al</span> binary, both at zero Kelvin and at finite temperature. First-principles density functional theory calculations of the energies of enumerated orderings on fcc and the sublattices of B2 not only predict the stability of known phases, but also reveal the stability of a family of ordered phases that combine features of L 12 and L 10 in different ratios to adjust their overall composition. The calculations also confirm the stability of vacancy ordered B2 derivatives that are stable in the <span class="hlt">Al</span>-rich half of the phase diagram. We introduce strain order parameters to systematically analyze instabilities with respect to the Bain path connecting the fcc and bcc lattices. Many unstable orderings on both fcc and bcc are predicted around compositions of xNi=0.625 , where a martensitic phase transformation is known to occur. Cluster expansion techniques together with Monte Carlo simulations were used to calculate a finite-temperature-composition phase diagram of the Ni-<span class="hlt">Al</span> binary. The calculated phase diagram together with an analysis of Bain instabilities reveals the importance of anharmonicity in determining the phase bounds between the B2 based β phase and the L 12 based γ' phase, as well as properties related to martensitic transformations that are observed upon quenching Ni-rich β .</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/22907449','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/22907449"><span>Catalytic oxidation with <span class="hlt">Al</span>-Ce-Fe-PILC as a post-treatment <span class="hlt">system</span> for coffee wet processing wastewater.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Sanabria, Nancy R; Peralta, Yury M; Montañez, Mardelly K; Rodríguez-Valencia, Nelson; Molina, Rafael; Moreno, Sonia</p> <p>2012-01-01</p> <p>The effluent from the anaerobic biological treatment of coffee wet processing wastewater (CWPW) contains a non-biodegradable compound that must be treated before it is discharged into a water source. In this paper, the wet hydrogen peroxide catalytic oxidation (WHPCO) process using <span class="hlt">Al</span>-Ce-Fe-PILC catalysts was researched as a post-treatment <span class="hlt">system</span> for CWPW and tested in a semi-batch reactor at atmospheric pressure and 25 °C. The <span class="hlt">Al</span>-Ce-Fe-PILC achieved a high conversion rate of total phenolic compounds (70%) and mineralization to CO(2) (50%) after 5 h reaction time. The chemical oxygen demand (COD) of coffee processing wastewater after wet hydrogen peroxide catalytic oxidation was reduced in 66%. The combination of the two treatment methods, biological (developed by Cenicafé) and catalytic oxidation with <span class="hlt">Al</span>-Ce-Fe-PILC, achieved a 97% reduction of COD in CWPW. Therefore, the WHPCO using <span class="hlt">Al</span>-Ce-Fe-PILC catalysts is a viable alternative for the post-treatment of coffee processing wastewater.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/pages/biblio/1321965-structural-ordering-solid-liquid-interfaces-al-sm-system-molecular-dynamics-study','SCIGOV-DOEP'); return false;" href="https://www.osti.gov/pages/biblio/1321965-structural-ordering-solid-liquid-interfaces-al-sm-system-molecular-dynamics-study"><span>Structural ordering at solid-liquid interfaces in <span class="hlt">Al</span>-Sm <span class="hlt">system</span>: A molecular-dynamics study</span></a></p> <p><a target="_blank" href="http://www.osti.gov/pages">DOE PAGES</a></p> <p>Sun, Yang; Zhang, Feng; Ye, Zhuo; ...</p> <p>2016-07-12</p> <p>The structural ordering at solid-liquid interfaces far from equilibrium is studied with molecular dynamics simulations for the <span class="hlt">Al</span>-Sm <span class="hlt">system</span>. Using the van-Hove self-correlation function as the criterion to identify attachment/detachment events that occur at the interface, we are able to determine the time-dependent interface position, and characterize the detailed interfacial structure ordering surrounding the attached atoms. For the interface between an undercooled <span class="hlt">Al</span>90Sm10 liquid and a metastable cubic structure, the solid induces the crystalline order of the cubic phase in the liquid layers, promoting the continuous growth of the crystal phase. When the same liquid is put in contact withmore » f.c.c. <span class="hlt">Al</span>, Sm from the liquid can still attach to the solid interface despite its insolubility in the <span class="hlt">Al</span> lattice. Non-f.c.c. order is revealed surrounding the attached Sm atoms. Lastly, we show that the local structure ordering at interface is highly correlated to solid packing and liquid ordering.« less</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2010ApPhA..99..607V','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2010ApPhA..99..607V"><span>Investigation of the ɛ phase in the Fe-<span class="hlt">Al</span> <span class="hlt">system</span> by high-temperature neutron diffraction</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Vogel, Sven C.; Stein, Frank; Palm, Martin</p> <p>2010-06-01</p> <p>In the central part of the Fe-<span class="hlt">Al</span> <span class="hlt">system</span> between about 58 and 65 at.% <span class="hlt">Al</span>, a high-temperature phase denoted as ɛ occurs with a hitherto unknown crystallographic structure. The phase is stable between 1231°C and 1095°C. In order to study the crystallographic structure of the ɛ phase, in situ high-temperature neutron time-of-flight diffraction experiments have been performed at the HIPPO instrument at the Los Alamos Neutron Science Center (LANSCE). The ɛ phase was found to have the formula Fe5<span class="hlt">Al</span>8 with a body-centred cubic structure of the Hume-Rothery Cu5Zn8 type (Ibar{4}3m (No. 217), Z=4, cI52) and 52 atoms in the unit cell. Its lattice parameter is a=8.9756(2) Å at 1120°C, which is 3.02 times that of cubic Fe<span class="hlt">Al</span> (B2) at the same temperature. We report here the evolution of the crystallographic parameters over the temperature range between 1080°C and 1120°C.</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li><a href="#" onclick='return showDiv("page_22");'>22</a></li> <li class="active"><span>23</span></li> <li><a href="#" onclick='return showDiv("page_24");'>24</a></li> <li><a href="#" onclick='return showDiv("page_25");'>25</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_23 --> <div id="page_24" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li><a href="#" onclick='return showDiv("page_22");'>22</a></li> <li><a href="#" onclick='return showDiv("page_23");'>23</a></li> <li class="active"><span>24</span></li> <li><a href="#" onclick='return showDiv("page_25");'>25</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="461"> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/scitech/biblio/1321965','SCIGOV-STC'); return false;" href="https://www.osti.gov/scitech/biblio/1321965"><span>Structural ordering at solid-liquid interfaces in <span class="hlt">Al</span>-Sm <span class="hlt">system</span>: A molecular-dynamics study</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Sun, Yang; Zhang, Feng; Ye, Zhuo; Ding, Zejun; Mendelev, Mikhail I.; Kramer, Matthew J.; Wang, Cai -Zhuang; Ho, Kai -Ming</p> <p>2016-07-12</p> <p>The structural ordering at solid-liquid interfaces far from equilibrium is studied with molecular dynamics simulations for the <span class="hlt">Al</span>-Sm <span class="hlt">system</span>. Using the van-Hove self-correlation function as the criterion to identify attachment/detachment events that occur at the interface, we are able to determine the time-dependent interface position, and characterize the detailed interfacial structure ordering surrounding the attached atoms. For the interface between an undercooled <span class="hlt">Al</span>90Sm10 liquid and a metastable cubic structure, the solid induces the crystalline order of the cubic phase in the liquid layers, promoting the continuous growth of the crystal phase. When the same liquid is put in contact with f.c.c. <span class="hlt">Al</span>, Sm from the liquid can still attach to the solid interface despite its insolubility in the <span class="hlt">Al</span> lattice. Non-f.c.c. order is revealed surrounding the attached Sm atoms. Lastly, we show that the local structure ordering at interface is highly correlated to solid packing and liquid ordering.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4288082','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4288082"><span>Factors Associated With Adoption of the Electronic Health Record <span class="hlt">System</span> Among <span class="hlt">Primary</span> Care Physicians</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Cheung, Clement SK; Tong, Ellen LH; Cheung, Ngai Tseung; Chan, Wai Man; Wang, Harry HX; Kwan, Mandy WM; Fan, Carmen KM; Liu, Kirin QL</p> <p>2013-01-01</p> <p>Background A territory-wide Internet-based electronic patient record allows better patient care in different sectors. The engagement of private physicians is one of the major facilitators for implementation, but there is limited information about the current adoption level of electronic medical record (eMR) among private <span class="hlt">primary</span> care physicians. Objective This survey measured the adoption level, enabling factors, and hindering factors of eMR, among private physicians in Hong Kong. It also evaluated the key functions and the popularity of electronic <span class="hlt">systems</span> and vendors used by these private practitioners. Methods A central registry consisting of 4324 private practitioners was set up. Invitations for self-administered surveys and the completed questionnaires were sent and returned via fax, email, postal mail, and on-site clinic visits. Current users and non-users of eMR <span class="hlt">system</span> were compared according to their demographic and practice characteristics. Student’s t tests and chi-square tests were used for continuous and categorical variables, respectively. Results A total of 524 completed surveys (response rate 524/4405 11.90%) were collected. The proportion of using eMR in private clinics was 79.6% (417/524). When compared with non-users, the eMR users were younger (users: 48.4 years SD 10.6 years vs non-users: 61.7 years SD 10.2 years, P<.001); more were female physicians (users: 80/417, 19.2% vs non-users: 14/107, 13.1%, P=.013); possessed less clinical experience (with more than20 years of practice: users: 261/417, 62.6% vs non-user: 93/107, 86.9%, P<.001); fewer worked under a Health Maintenance Organization (users: 347/417, 83.2% vs non-users: 97/107, 90.7%, P<.001) and more worked with practice partners (users: 126/417, 30.2% vs non-users: 4/107, 3.7%, P<.001). Efficiency (379/417, 90.9%) and reduction of medical errors (229/417, 54.9%) were the major enabling factors, while patient-unfriendliness (58/107, 54.2%) and limited consultation time (54/107, 50</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3750424','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3750424"><span>Reforming healthcare <span class="hlt">systems</span> on a locally integrated basis: is there a potential for increasing collaborations in <span class="hlt">primary</span> healthcare?</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p></p> <p>2013-01-01</p> <p>. This is with the exception of private medical clinics, where collaborations decreased both outside and within LHNs. Conclusion Health <span class="hlt">system</span> reforms aimed at creating geographically based networks influenced <span class="hlt">primary</span> healthcare practices’ both among themselves (horizontal collaborations) and with hospitals (vertical collaborations). There is evidence of increased collaborations within defined geographic areas, particularly among new type of <span class="hlt">primary</span> healthcare. PMID:23835105</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25824838','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25824838"><span>The Cp<span class="hlt">AL</span> quorum sensing <span class="hlt">system</span> regulates production of hemolysins CPA and PFO to build Clostridium perfringens biofilms.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Vidal, Jorge E; Shak, Joshua R; Canizalez-Roman, Adrian</p> <p>2015-06-01</p> <p>Clostridium perfringens strains produce severe diseases, including myonecrosis and enteritis necroticans, in humans and animals. Diseases are mediated by the production of potent toxins that often damage the site of infection, e.g., skin epithelium during myonecrosis. In planktonic cultures, the regulation of important toxins, such as CPA, CPB, and PFO, is controlled by the C. perfringens Agr-like (Cp<span class="hlt">AL</span>) quorum sensing (QS) <span class="hlt">system</span>. Strains also encode a functional LuxS/AI-2 <span class="hlt">system</span>. Although C. perfringens strains form biofilm-like structures, the regulation of biofilm formation is poorly understood. Therefore, our studies investigated the role of Cp<span class="hlt">AL</span> and LuxS/AI-2 QS <span class="hlt">systems</span> and of QS-regulated factors in controlling the formation of biofilms. We first demonstrate that biofilm production by reference strains differs depending on the culture medium. Increased biomass correlated with the presence of extracellular DNA in the supernatant, which was released by lysis of a fraction of the biofilm population and planktonic cells. Whereas ΔagrB mutant strains were not able to produce biofilms, a ΔluxS mutant produced wild-type levels. The transcript levels of Cp<span class="hlt">AL</span>-regulated cpa and pfoA genes, but not cpb, were upregulated in biofilms compared to planktonic cultures. Accordingly, Δcpa and ΔpfoA mutants, in type A (S13) or type C (CN3685) backgrounds, were unable to produce biofilms, whereas CN3685Δcpb made wild-type levels. Biofilm formation was restored in complemented Δcpa/cpa and ΔpfoA/pfoA strains. Confocal microscopy studies further detected CPA partially colocalizing with eDNA on the biofilm structure. Thus, Cp<span class="hlt">AL</span> regulates biofilm formation in C. perfringens by increasing levels of certain toxins required to build biofilms.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4432755','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4432755"><span>The Cp<span class="hlt">AL</span> Quorum Sensing <span class="hlt">System</span> Regulates Production of Hemolysins CPA and PFO To Build Clostridium perfringens Biofilms</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Shak, Joshua R.; Canizalez-Roman, Adrian</p> <p>2015-01-01</p> <p>Clostridium perfringens strains produce severe diseases, including myonecrosis and enteritis necroticans, in humans and animals. Diseases are mediated by the production of potent toxins that often damage the site of infection, e.g., skin epithelium during myonecrosis. In planktonic cultures, the regulation of important toxins, such as CPA, CPB, and PFO, is controlled by the C. perfringens Agr-like (Cp<span class="hlt">AL</span>) quorum sensing (QS) <span class="hlt">system</span>. Strains also encode a functional LuxS/AI-2 <span class="hlt">system</span>. Although C. perfringens strains form biofilm-like structures, the regulation of biofilm formation is poorly understood. Therefore, our studies investigated the role of Cp<span class="hlt">AL</span> and LuxS/AI-2 QS <span class="hlt">systems</span> and of QS-regulated factors in controlling the formation of biofilms. We first demonstrate that biofilm production by reference strains differs depending on the culture medium. Increased biomass correlated with the presence of extracellular DNA in the supernatant, which was released by lysis of a fraction of the biofilm population and planktonic cells. Whereas ΔagrB mutant strains were not able to produce biofilms, a ΔluxS mutant produced wild-type levels. The transcript levels of Cp<span class="hlt">AL</span>-regulated cpa and pfoA genes, but not cpb, were upregulated in biofilms compared to planktonic cultures. Accordingly, Δcpa and ΔpfoA mutants, in type A (S13) or type C (CN3685) backgrounds, were unable to produce biofilms, whereas CN3685Δcpb made wild-type levels. Biofilm formation was restored in complemented Δcpa/cpa and ΔpfoA/pfoA strains. Confocal microscopy studies further detected CPA partially colocalizing with eDNA on the biofilm structure. Thus, Cp<span class="hlt">AL</span> regulates biofilm formation in C. perfringens by increasing levels of certain toxins required to build biofilms. PMID:25824838</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2011SPIE.7995E..0NL','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2011SPIE.7995E..0NL"><span>Research on the reflection coating at three wavelengths for <span class="hlt">primary</span> reflector of the optical antenna in the laser communication <span class="hlt">systems</span></span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Liu, Huasong; Liu, Muxiao; Wang, Zhanshan; Ji, Yiqin; Lu, Jiangtao</p> <p>2011-02-01</p> <p><span class="hlt">Primary</span> reflector of the optical antenna is a key component in the space laser communication <span class="hlt">systems</span>, and multi-wavelengths laser need to be worked in the common aperture. Reflection coating is designed for the <span class="hlt">primary</span> reflector of a laser communication <span class="hlt">system</span>, which can work at three wavelengths (633nm, 808nm, 1550nm), the designed target reflectance are R633nm>=50%, R808nm>=99% and R1550nm>=99% at angle of incidence from 0 to 20 deg. We selected Ta2O5 and SiO2 as the high refractive index and low refractive index coating materials, analyzed the impact on the reflection coating of the <span class="hlt">systemic</span> errors and random errors, and determined the manufacture error of the coater <span class="hlt">system</span> which can't greater than 1%. The Ion beam sputtering deposition technique was used to manufacture reflection coating for three-wavelengths and a LAMBDA900 spectrophotometer was used to analysis the reflectance at three wavelengths which achieved the design requirements. Finally we give the origin of manufacture error source for this high reflection coating. The reflection coating component was successfully used in the <span class="hlt">primary</span> reflector of the optical antenna of the laser communication <span class="hlt">systems</span>.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2010SPIE.7995E..0NL','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2010SPIE.7995E..0NL"><span>Research on the reflection coating at three wavelengths for <span class="hlt">primary</span> reflector of the optical antenna in the laser communication <span class="hlt">systems</span></span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Liu, Huasong; Liu, Muxiao; Wang, Zhanshan; Ji, Yiqin; Lu, Jiangtao</p> <p>2010-10-01</p> <p><span class="hlt">Primary</span> reflector of the optical antenna is a key component in the space laser communication <span class="hlt">systems</span>, and multi-wavelengths laser need to be worked in the common aperture. Reflection coating is designed for the <span class="hlt">primary</span> reflector of a laser communication <span class="hlt">system</span>, which can work at three wavelengths (633nm, 808nm, 1550nm), the designed target reflectance are R633nm>=50%, R808nm>=99% and R1550nm>=99% at angle of incidence from 0 to 20 deg. We selected Ta2O5 and SiO2 as the high refractive index and low refractive index coating materials, analyzed the impact on the reflection coating of the <span class="hlt">systemic</span> errors and random errors, and determined the manufacture error of the coater <span class="hlt">system</span> which can't greater than 1%. The Ion beam sputtering deposition technique was used to manufacture reflection coating for three-wavelengths and a LAMBDA900 spectrophotometer was used to analysis the reflectance at three wavelengths which achieved the design requirements. Finally we give the origin of manufacture error source for this high reflection coating. The reflection coating component was successfully used in the <span class="hlt">primary</span> reflector of the optical antenna of the laser communication <span class="hlt">systems</span>.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28109684','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28109684"><span>Increase in the <span class="hlt">systemic</span> exposure of <span class="hlt">primary</span> metabolites of Midazolam in rat arising from CYP inhibition or hepatic dysfunction.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Hasegawa, Tsubasa; Nakanishi, Satomi; Minami, Keiko; Higashino, Haruki; Kataoka, Makoto; Shitara, Yoshihisa; Yamashita, Shinji</p> <p>2017-02-01</p> <p>The main purpose of this study is to demonstrate the possibility of increase in the <span class="hlt">systemic</span> exposure of drug metabolites by CYP-inhibition or acute hepatitis. Midazolam (MDZ) was used as a model substrate of CYP3A and 1-aminobenzotriazole (ABT) was used as a CYP-inhibitor. After oral pretreatment with ABT, MDZ was intravenously injected to rats and the plasma profiles of MDZ and its <span class="hlt">primary</span> metabolites, 1'-hydroxy MDZ and 4-hydroxy MDZ, were observed. In the ABT-pretreatment rats, plasma AUCs of both metabolites were much larger than those in control rats, demonstrating a higher <span class="hlt">systemic</span> exposure of metabolites under CYP-inhibited condition. Furthermore, kinetic analysis revealed that the amount of both metabolites entered into the <span class="hlt">systemic</span> circulation increased significantly (about 5-times). Increases in the <span class="hlt">systemic</span> exposure of the <span class="hlt">primary</span> metabolites of MDZ were also observed in the acute hepatitis rats induced by CCl4-pretreatment. As underlying mechanisms, it was speculated that ABT inhibited the subsequent metabolism of <span class="hlt">primary</span> metabolites of MDZ in the hepatocytes and enhanced their release to the <span class="hlt">systemic</span> circulation. In vitro study with rat liver microsomes supported this speculation. In conclusion, this study showed the complexity of PK profiles of drug metabolites, which might lead to new aspects on their safety issue.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/scitech/biblio/22345239','SCIGOV-STC'); return false;" href="https://www.osti.gov/scitech/biblio/22345239"><span>Phase and structural behavior of Sm<span class="hlt">Al</span>O{sub 3}–RAlO{sub 3} (R = Eu, Gd) <span class="hlt">systems</span></span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Ohon, N.; Vasylechko, L.; Prots, Yu.; Schmidt, M.</p> <p>2014-02-01</p> <p>Highlights: • Continuous solid solutions exist in the Sm<span class="hlt">Al</span>O{sub 3}–RAlO{sub 3} (R = Eu, Gd) <span class="hlt">systems</span>. • Lattice parameter crossover was found in solid solutions Sm{sub 1−x}R{sub x}<span class="hlt">Al</span>O{sub 3} (R = Eu, Gd). • Thermally induced lattice crossovers occur in Sm{sub 0.9}R{sub 0.1}<span class="hlt">Al</span>O{sub 3} at elevated temperatures. • First-order structural phase transition Pbnm↔R3{sup ¯}c was found in Sm{sub 1−x}R{sub x}<span class="hlt">Al</span>O{sub 3} (R = Eu, Gd). • Phase diagram of the <span class="hlt">systems</span> Sm<span class="hlt">Al</span>O{sub 3}–Eu<span class="hlt">Al</span>O{sub 3} and Sm<span class="hlt">Al</span>O{sub 3}–Gd<span class="hlt">Al</span>O{sub 3} has been constructed. - Abstract: Phase and structural behavior in the Sm<span class="hlt">Al</span>O{sub 3}–RAlO{sub 3} (R = Eu, Gd) <span class="hlt">systems</span> has been studied in a whole concentration range by means of laboratory X-ray diffraction, in situ synchrotron powder diffraction and differential thermal analysis techniques. Continuous solid solutions with orthorhombic perovskite structure have been found in both <span class="hlt">systems</span>. Peculiarity of the solid solutions of Sm{sub 1−x}Eu{sub x}<span class="hlt">Al</span>O{sub 3} and Sm{sub 1−x}Gd{sub x}<span class="hlt">Al</span>O{sub 3} is the existence of two lattice parameter crossovers in each <span class="hlt">system</span> occurred at x{sub Eu} = 0.07 and 0.62 and at x{sub Gd} = 0.04 and 0.33, respectively. The temperature induced lattice crossovers in the Sm{sub 0.9}Eu{sub 0.1}<span class="hlt">Al</span>O{sub 3} and Sm{sub 0.9}Gd{sub 0.1}<span class="hlt">Al</span>O{sub 3} samples have been found at 387 and 922 K and at 501 and 894 K. First-order reversible structural phase transformations Pbnm↔R3{sup ¯}c have been detected in both <span class="hlt">systems</span> at the elevated temperatures. The temperatures of these transitions increase linearly with the decreasing of the samarium content. Phase diagrams of the pseudo-binary <span class="hlt">systems</span> Sm<span class="hlt">Al</span>O{sub 3}–Eu<span class="hlt">Al</span>O{sub 3} and Sm<span class="hlt">Al</span>O{sub 3}–Gd<span class="hlt">Al</span>O{sub 3} have been constructed.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015AIPC.1665e0175J','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015AIPC.1665e0175J"><span>Influence of <span class="hlt">Al</span>2O3 nano-filler on dielectric properties and conductivity of two different PVA-PEO blend <span class="hlt">systems</span></span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Joge, Prajakta; Kanchan, D. K.; Dave, Gargi</p> <p>2015-06-01</p> <p><span class="hlt">System</span>-1: PVA-PEO-PEG-AgNO3 and <span class="hlt">System</span>-2: PVA-PEO-EC-LiCF3SO3, are two blend <span class="hlt">systems</span> prepared for different concentrations of <span class="hlt">Al</span>2O3 nano-filler ranging from 2 to 10 wt%. The effect of <span class="hlt">Al</span>2O3 nano filler on the conductivity (σdc) and dielectric properties such as dielectric constant (ɛ') and dielectric loss (ɛ") of the <span class="hlt">systems</span> is thoroughly investigated using impedance spectroscopic analysis technique.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/21636340','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/21636340"><span>[<span class="hlt">Primary</span> hyperoxaluria].</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Cochat, Pierre; Fargue, Sonia; Bacchetta, Justine; Bertholet-Thomas, Aurélia; Sabot, Jean-François; Harambat, Jérôme</p> <p>2011-07-01</p> <p><span class="hlt">Primary</span> hyperoxalurias are rare recessive inherited inborn errors of glyoxylate metabolism. They are responsible for progressive renal involvement, which further lead to <span class="hlt">systemic</span> oxalate deposition, which can even occur in infants. <span class="hlt">Primary</span> hyperoxaluria type 1 is the most common form in Europe and is due to alanine-glyoxylate aminostransferase deficiency, a hepatic peroxisomal pyridoxin-dependent enzyme. Therefore <span class="hlt">primary</span> hyperoxaluria type 1 is responsible for hyperoxaluria leading to aggressive stone formation and nephrocalcinosis. As glomerular filtration rate decreases, <span class="hlt">systemic</span> oxalate storage occurs throughout all the body, and mainly in the skeleton. The diagnosis is first based on urine oxalate measurement, then on genotyping, which may also allow prenatal diagnosis to be proposed. Conservative measures - including hydration, crystallization inhibitors and pyridoxine - are safe and may allow long lasting renal survival, provided it is given as soon as the diagnosis has been even suspected. No dialysis procedure can remove enough oxalate to compensate oxalate overproduction from the sick liver, therefore a combined liver and kidney transplantation should be planned before advanced renal disease has occurred, in order to limit/avoid <span class="hlt">systemic</span> oxalate deposition. In the future, <span class="hlt">primary</span> hyperoxaluria type 1 may benefit from hepatocyte transplantation, chaperone molecules, etc.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015PhDT.......137K','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015PhDT.......137K"><span>Design and evaluation of a <span class="hlt">primary</span>/secondary pumping <span class="hlt">system</span> for a heat pump assisted solar thermal loop</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Krockenberger, Kyle G.</p> <p></p> <p>A heat pump assisted solar thermal <span class="hlt">system</span> was designed, commissioned, tested and analyzed over a period of two years. The unique <span class="hlt">system</span> uses solar energy whenever it is available, but switches to heat pump mode at night or whenever there is a lack of solar energy. The solar thermal energy is added by a variety of flat plat solar collectors and an evacuated tube heat pipe solar collector. The working medium in the entire <span class="hlt">system</span> is a 50% mixture of propylene glycol and water for freeze protection. During the design and evaluation the <span class="hlt">primary</span> / secondary pumping <span class="hlt">system</span> was the focus of the evaluation. Testing within this research focused on the operation modes, pump stability, and <span class="hlt">system</span> efficiency. It was found that the <span class="hlt">system</span> was in full operation, the pumps were stable and that the efficiency factor of the <span class="hlt">system</span> was 1.95.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4616419','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4616419"><span>An Update of the Mayo Clinic Cohort of Patients With Adult <span class="hlt">Primary</span> Central Nervous <span class="hlt">System</span> Vasculitis</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Salvarani, Carlo; Brown, Robert D.; Christianson, Teresa; Miller, Dylan V.; Giannini, Caterina; Huston, John; Hunder, Gene G.</p> <p>2015-01-01</p> <p>Abstract <span class="hlt">Primary</span> central nervous <span class="hlt">system</span> vasculitis (PCNSV) is an uncommon condition in which lesions are limited to vessels of the brain and spinal cord. Because the clinical manifestations are not specific, the diagnosis is often difficult, and permanent disability and death are frequent outcomes. This study is based on a cohort of 163 consecutive patients with PCNSV who were examined at the Mayo Clinic over a 29-year period from 1983 to 2011. The aim of the study was to define the characteristics of these patients, which represents the largest series in adults reported to date. A total of 105 patients were diagnosed by angiographic findings and 58 by biopsy results. The patients diagnosed by biopsy more frequently had at presentation cognitive dysfunction, greater cerebrospinal fluid total protein concentrations, less frequent cerebral infarcts, and more frequent leptomeningeal gadolinium-enhanced lesions on magnetic resonance imaging (MRI), along with less mortality and disability at last follow-up. The patients diagnosed by angiograms more frequently had at presentation hemiparesis or a persistent neurologic deficit or stroke, more frequent infarcts on MRI and an increased mortality. These differences were mainly related to the different size of the vessels involved in the 2 groups. Although most patients responded to therapy with glucocorticoids alone or in conjunction with cyclophosphamide and tended to improve during the follow-up period, an overall increased mortality rate was observed. Relapses occurred in one-quarter of the patients and were less frequent in patients treated with prednisone and cyclophosphamide compared with those treated with prednisone alone. The mortality rate and degree of disability at last follow-up were greater in those with increasing age, cerebral infarctions on MRI, angiographic large vessel involvement, and diagnosis made by angiography alone, but were lower in those with gadolinium-enhanced lesions on MRI and in those with</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/16107291','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/16107291"><span>A baseline survey of the <span class="hlt">Primary</span> Healthcare <span class="hlt">system</span> in south eastern Nigeria.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Chukwuani, Chinyere Mercellina; Olugboji, Akindeji; Akuto, Edward Erdorga; Odebunmi, Akim; Ezeilo, Ezenta; Ugbene, Emmanuel</p> <p>2006-07-01</p> <p>A baseline survey to audit the PHC operations and determine community perception and expectations of PHC service delivery was conducted in 72 communities in Enugu state, southeastern Nigeria. The study was intended to facilitate the development of intermediate performance indicators for monitoring the progress of an ongoing health sector reform and to gather baseline data for planning and policy formulation. The tools used for the operations audit assessed indicators for evaluating: (a) Stewardship, (b) Service Provision and (c) Administrative and financial management; while the community survey was assessed by, (a) utilization of health services, (b) perception of service delivery and (c) health care financing. One hundred and sixteen respondents from each of the facilities in the sample frame were interviewed using a structured self-assessment questionnaire and a qualitative assessment was undertaken in 53 of the facilities using an audit guide. Focus group discussions (FGD) were conducted with the policy makers and planners in each of the 17 LGAs in the state. A total of 832 respondents were interviewed in the communities (using a structured questionnaire) and 42 community FGDs were conducted. The results indicate a lack of operational efficiency in the majority of the facilities audited. It was also observed that majority of the facilities do not provide all services required of it, are poorly maintained, do not have enough skilled health workers and operate without a budget. There appears to be no formal financial management <span class="hlt">system</span> in place and no policy on financial resource generation. The community survey identified two major problems; low utilization of PHCs and poor service provision. The key indicator identified by the community for evaluating performance of the PHCs remains "access to essential drugs". The major prospect was the willingness of an appreciable number of respondents to invest in health financing through insurance schemes and payment of</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/19488500','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/19488500"><span>The role of the Family Health Program in the organization of <span class="hlt">primary</span> care in municipal health <span class="hlt">systems</span>.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Medina, Maria Guadalupe; Hartz, Zulmira Maria de Araújo</p> <p>2009-05-01</p> <p>The contribution of <span class="hlt">primary</span> care to population health and health <span class="hlt">systems</span> organization has been well documented, but some authors have highlighted that in Third World countries it has gained more ground in discourse than in facts and practices, with different possible configurations. The objectives of the current study were to evaluate and correlate organizational and local contextual characteristics to the degree of implementation of <span class="hlt">primary</span> care in two municipalities (counties) in the State of Bahia State, Brazil, that had adopted the Family Health Program (FHP) as the <span class="hlt">system</span>'s central thrust. The research was based on two case studies with interwoven levels of analysis, using as the point of departure the underlying goal-image of <span class="hlt">primary</span> care in the definition of criteria and standards for degree of implementation. The total scores for Municipalities A and B were 66 and 81, respectively (maximum total score = 100), while differences were observed between the urban and rural teams. The political and institutional contexts helped explain differences in the degree of implementation of <span class="hlt">primary</span> care, but regardless of the municipal context, the study showed the emergence of organizational innovations closely related to the FHP.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015AIPA....5h7149A','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015AIPA....5h7149A"><span>Electrical properties of GaAs metal-oxide-semiconductor structure comprising <span class="hlt">Al</span>2O3 gate oxide and <span class="hlt">Al</span>N passivation layer fabricated in situ using a metal-organic vapor deposition/atomic layer deposition hybrid <span class="hlt">system</span></span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Aoki, Takeshi; Fukuhara, Noboru; Osada, Takenori; Sazawa, Hiroyuki; Hata, Masahiko; Inoue, Takayuki</p> <p>2015-08-01</p> <p>This paper presents a compressive study on the fabrication and optimization of GaAs metal-oxide-semiconductor (MOS) structures comprising a <span class="hlt">Al</span>2O3 gate oxide, deposited via atomic layer deposition (ALD), with an <span class="hlt">Al</span>N interfacial passivation layer prepared in situ via metal-organic chemical vapor deposition (MOCVD). The established protocol afforded self-limiting growth of <span class="hlt">Al</span>2O3 in the atmospheric MOCVD reactor. Consequently, this enabled successive growth of MOCVD-formed <span class="hlt">Al</span>N and ALD-formed <span class="hlt">Al</span>2O3 layers on the GaAs substrate. The effects of <span class="hlt">Al</span>N thickness, post-deposition anneal (PDA) conditions, and crystal orientation of the GaAs substrate on the electrical properties of the resulting MOS capacitors were investigated. Thin <span class="hlt">Al</span>N passivation layers afforded incorporation of optimum amounts of nitrogen, leading to good capacitance-voltage (C-V) characteristics with reduced frequency dispersion. In contrast, excessively thick <span class="hlt">Al</span>N passivation layers degraded the interface, thereby increasing the interfacial density of states (Dit) near the midgap and reducing the conduction band offset. To further improve the interface with the thin <span class="hlt">Al</span>N passivation layers, the PDA conditions were optimized. Using wet nitrogen at 600 °C was effective to reduce Dit to below 2 × 1012 cm-2 eV-1. Using a (111)A substrate was also effective in reducing the frequency dispersion of accumulation capacitance, thus suggesting the suppression of traps in GaAs located near the dielectric/GaAs interface. The current findings suggest that using an atmosphere ALD process with in situ <span class="hlt">Al</span>N passivation using the current MOCVD <span class="hlt">system</span> could be an efficient solution to improving GaAs MOS interfaces.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2010MMI....16..987P','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2010MMI....16..987P"><span>The effect of boron oxide on the crystallization behavior of Mg<span class="hlt">Al</span>2O4 spinel phase during the cooling of the CaO-SiO2-10 mass.% MgO-30 mass.%<span class="hlt">Al</span>2O3 <span class="hlt">systems</span></span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Park, Joo Hyun</p> <p>2010-12-01</p> <p>The microstructural characteristics of the CaO-SiO2-B2O3-10 mass.% MgO-30 mass.% <span class="hlt">Al</span>2O3 <span class="hlt">systems</span> solidified during slow cooling from 1600 °C were investigated using SEM-EDS and a thermochemical computation package. The effect of boron oxide on the crystallization behavior of the spinel in the aluminosilicate <span class="hlt">system</span> was observed because boron oxide is believed to become a potential flux to reduce the melting point of the liquid oxides. The <span class="hlt">primary</span> crystalline phase was spinel, mainly Mg<span class="hlt">Al</span>2O4, irrespective of the boron content. The liquidus temperature T L continuously decreased as the boron oxide content increased, indicating that the boron oxide decreased the activity of the Mg<span class="hlt">Al</span>2O4 spinel phase in liquid melts at high temperatures. The size of the spinel crystals increased as the temperature range for the solid + liquid coexisting region, viz. the mushy zone, increased. In the present <span class="hlt">systems</span>, because the T L continuously decreased with the increase in the boron oxide content, the viscosity of the liquid oxide may have affected the crystallization behavior of the spinel during cooling. Based on these results, an injection of a small amount of B2O3 flux into molten steel containing liquid aluminosilicate inclusions is not recommended because large spinel crystals can originate from the changes in the thermophysical properties of the liquid inclusions due to the incorporation of boron oxide into the aluminosilicate networks.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/scitech/biblio/22273493','SCIGOV-STC'); return false;" href="https://www.osti.gov/scitech/biblio/22273493"><span>Morphology and properties of a hybrid organic-inorganic <span class="hlt">system</span>: <span class="hlt">Al</span> nanoparticles embedded into CuPc thin film</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Molodtsova, O. V.; Babenkov, S. V.; Aristova, I. M.; Vilkov, O. V.; Aristov, V. Yu.</p> <p>2014-04-28</p> <p>The evolution of the morphology and the electronic structure of the hybrid organic-inorganic <span class="hlt">system</span> composed of aluminum nanoparticles (NPs) distributed in an organic semiconductor matrix—copper phthalocyanine (CuPc)—as a function of nominal aluminum content was studied by transmission electron microscopy and by photoemission spectroscopy methods. The aluminum atoms deposited onto the CuPc surface diffuse into the organic matrix and self-assemble to NPs in a well-defined manner with a narrow diameter distribution, which depends on the amount of aluminum that is evaporated onto the CuPc film. We find clear evidence of a charge transfer from <span class="hlt">Al</span> to CuPc and we have been able to determine the lattice sites where <span class="hlt">Al</span> ions sit. The finally at high coverage about 64 Å the formation of metallic aluminum overlayer on CuPc thin film takes place.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/18061425','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/18061425"><span>The <span class="hlt">primary</span> cilia, a 'Rab-id' transit <span class="hlt">system</span> for hedgehog signaling.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Oro, Anthony E</p> <p>2007-12-01</p> <p>Intense focus has been centered around how the <span class="hlt">primary</span> cilia transduces the hedgehog (Hh) signal from smoothened (Smo) to the Gli transcription factors. New data indicate that ligand and signaling lipids help regulate small GTPase-dependent accumulation and activity of signaling components.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=International+AND+Journal+AND+Current+AND+Research&pg=3&id=EJ953776','ERIC'); return false;" href="http://eric.ed.gov/?q=International+AND+Journal+AND+Current+AND+Research&pg=3&id=EJ953776"><span>Structures and <span class="hlt">Systems</span> and Bodies and Things: Historical Research on <span class="hlt">Primary</span> Schooling and Its Professional Relevance</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Cunningham, Peter</p> <p>2012-01-01</p> <p>Recalling its origins as a research journal addressing educationists this article seeks to understand historical research published in "History of Education" as aimed at a professional audience. <span class="hlt">Primary</span> schooling provides a significant focus as the study of education history was fostered especially in the training of elementary…</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li><a href="#" onclick='return showDiv("page_22");'>22</a></li> <li><a href="#" onclick='return showDiv("page_23");'>23</a></li> <li class="active"><span>24</span></li> <li><a href="#" onclick='return showDiv("page_25");'>25</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_24 --> <div id="page_25" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li><a href="#" onclick='return showDiv("page_22");'>22</a></li> <li><a href="#" onclick='return showDiv("page_23");'>23</a></li> <li><a href="#" onclick='return showDiv("page_24");'>24</a></li> <li class="active"><span>25</span></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="481"> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=law+AND+obligation&pg=4&id=EJ864915','ERIC'); return false;" href="http://eric.ed.gov/?q=law+AND+obligation&pg=4&id=EJ864915"><span>State Liability for Abuse in <span class="hlt">Primary</span> Schools: <span class="hlt">Systemic</span> Failure and "O'Keeffe" v. "Hickey"</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>O'Mahony, Conor</p> <p>2009-01-01</p> <p>Due to the historical arrangement between Church and State, the Irish State has always discharged its duty to provide for free <span class="hlt">primary</span> education exclusively through the provision of funding to privately owned and managed schools. Consequently, in "O'Keeffe" v. "Hickey," where a woman sued the State in respect of sex abuse she…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://files.eric.ed.gov/fulltext/EJ990110.pdf','ERIC'); return false;" href="http://files.eric.ed.gov/fulltext/EJ990110.pdf"><span>Uneven Distribution of Novice Teachers in the Chilean <span class="hlt">Primary</span> School <span class="hlt">System</span></span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Meckes, Lorena; Bascope, Martin</p> <p>2012-01-01</p> <p>This study examines the allocation of novice <span class="hlt">primary</span> teachers in Chilean schools, looking at their characteristics and at the attributes of the schools at which they are hired after having completed their initial teacher training. The study reveals that in Chile, more qualified novice teachers are more prone to get jobs in socio-economically…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=narrative+AND+research&pg=3&id=EJ1041813','ERIC'); return false;" href="http://eric.ed.gov/?q=narrative+AND+research&pg=3&id=EJ1041813"><span>Student Transition from <span class="hlt">Primary</span> to Lower Secondary School in Cambodia: Narrative Insights into Complex <span class="hlt">Systems</span></span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Edwards, D. Brent, Jr.; Zimmermann, Thomas; Sitha, Chhinh; Williams, James H.; Kitamura, Yuto</p> <p>2014-01-01</p> <p>This article has three purposes. First, it presents findings from a study of student retention and dropout in Cambodia, as pupils transition from <span class="hlt">primary</span> to lower secondary school. Second, it aims to understand from an in-depth, emic perspective the dynamics of this process and the challenges that individual families and their students face around…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2012PhDT.......215L','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2012PhDT.......215L"><span>Approche thermodynamique de la corrosion des refractaires aluminosiliceux par le bain cryolithique : modelisation thermodynamique du <span class="hlt">systeme</span> quaternaire reciproque <span class="hlt">Al</span>F3-NaF-SiF 4-<span class="hlt">Al</span>2O3-Na2O-SiO2</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Lambotte, Guillaume</p> <p></p> <p>The main objective of this thesis is the thermodynamic modeling of liquid and solid solutions, the stoichiometric compounds and the gaseous phase of the chemical <span class="hlt">system</span> which represent the species involved in the corrosion of the refractory lining of the electrolysis cell. This chemical <span class="hlt">system</span> is the quaternary reciprocal <span class="hlt">system</span> <span class="hlt">Al</span>F3-NaF-SiF4-<span class="hlt">Al</span> 2O3-Na2O-SiO2 with aluminum and carbon. The modeling of the entire reciprocal <span class="hlt">system</span> has never been realized before and is very challenging due to the nature of the oxyfluoride solution. The thermodynamic modeling is based on Gibbs free energy functions coming from the theory of solutions. The central hypothesis of this project is that, if it is possible to reproduce the strong short-range ordering observed between the ions of the liquid solution, then reasonable results will be obtained for the phase equilibria involved in this chemical <span class="hlt">system</span>. The thermodynamic model used in this thesis is the Modified Quasichemical Model in the Quadruplet Approximation (MQMQA) which takes into account the short-range ordering between first- and also second-nearest-neighbors, and is the best suited to model the oxyfluoride liquid solution. First, the reciprocal <span class="hlt">system</span> with the most negative Gibbs free energy change for the exchange reaction between the end-members, NaF-SiF4-Na 2O-SiO2, was modeled, allowing thus the validation of the recent modifications of the MQMQA aimed at improving the modeling of the thermodynamic properties of reciprocal solutions presenting a strong short-range order among first-nearest neighbors as well as second-nearest neighbors. In order to model this <span class="hlt">system</span>, an estimate of the thermodynamic properties of the hypothetical SiF4 liquid was necessary. The experimental data in the binary <span class="hlt">systems</span> NaF-SiF4 and Na2O-SiO2 are reproduced within the experimental error limits. In the reciprocal <span class="hlt">system</span>, a group of data in conflict with all others could not be reproduced. The data considered reliable are well reproduced. A</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.osti.gov/scitech/servlets/purl/532645','SCIGOV-STC'); return false;" href="http://www.osti.gov/scitech/servlets/purl/532645"><span>VXI based multibunch detector and QPSK modulator for the PEP-II/<span class="hlt">ALS</span>/DA{Phi}NE longitudinal feedback <span class="hlt">system</span></span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Young, A.; Fox, J.; Teytelman, D.</p> <p>1997-04-01</p> <p>The PEP-II/<span class="hlt">ALS</span>/DA{Phi}NE feedback <span class="hlt">systems</span> are complex <span class="hlt">systems</span> implemented using analog, digital and microwave circuits. The VXI hardware implementation for the Front-end and Back-end analog processing modules is presented. The Front-end module produces a baseband beam phase signal from pickups using a microwave tone burst generator. The Back-end VXI module generates an AM/QPSK modulated signal from a baseband correction signal computed in a digital signal processor. These components are implemented in VXI packages that allow a wide spectrum of <span class="hlt">system</span> functions including a 120 MHz bandwidth rms detector, reference phase servo, woofer link to the RF control <span class="hlt">system</span>, standard VXI status/control, and user defined registers. The details of the design and implementation of the VXI modules including performance characteristics are presented.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/1997E%26PSL.153..209K','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/1997E%26PSL.153..209K"><span>Melting enthalpies of mantle peridotite: calorimetric determinations in the <span class="hlt">system</span> CaO-MgO-<span class="hlt">Al</span> 2O 3-SiO 2 and application to magma generation</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Kojitani, Hiroshi; Akaogi, Masaki</p> <p>1997-12-01</p> <p>High-temperature drop calorimetry in the temperature range of 1398-1785 K was performed for the samples of mixtures of synthetic anorthite (An), diopside (Di), enstatite (En) and forsterite (Fo) with the same compositions as those of <span class="hlt">primary</span> melts generated at 1.1, 3 and 4 GPa at most 10° above the solidus of anhydrous mantle peridotite in the CaO-MgO-<span class="hlt">Al</span> 2O 3-SiO 2 <span class="hlt">system</span>. From the differences between the heat contents ( H T-H 298) of liquid and that of crystal mixture at the liquidus temperature, melting enthalpies of the samples of 1.1, 3 and 4 GPa-<span class="hlt">primary</span> melt compositions were determined at 1 atm to be 531 ± 39 J · g -1 at 1583 K, 604 ± 21 J · g -1 at 1703 K, 646 ± 21 J · g -1 at 1753 K, respectively. These heat of fusion values suggest that mixing enthalpy of the melt in the An-Di-En-Fo <span class="hlt">system</span> is approximately zero within the experimental errors when we use the heat of fusion of Fo by Richet et <span class="hlt">al</span>. (P. Richet, F. Leclerc, L. Benoist, Melting of forsterite and spinel, with implications for the glass transition of Mg 2SiO 4 liquid, Geophys. Res. Lett. 20 (1993) 1675-1678). The measured enthalpies of melting at 1 atm were converted into those for melting reactions which occur under high pressures by correcting enthalpy changes associated with solid-state mineral reactions. Correcting the effects of pressure, temperature and FeO and Na 2O components on the melting enthalpies at 1 atm, heat of fusion values of a representative mantle peridotite just above the solidus under high pressure were estimated to be 590 J at 1.1 GPa and 1523 K, 692 J at 3 GPa and 1773 K, and 807 J at 4 GPa and 1923 K for melting reactions producing liquid of 1 g, with uncertainties of 50 J. By applying these melting enthalpies to a mantle diapir model which generates present MORBs, a potential mantle temperature of 1533 K has been estimated, assuming an eruption temperature of magma of 1473 K.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.osti.gov/scitech/servlets/purl/561197','SCIGOV-STC'); return false;" href="http://www.osti.gov/scitech/servlets/purl/561197"><span>Final report spent nuclear fuel retrieval <span class="hlt">system</span> <span class="hlt">primary</span> cleaning development testing</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Ketner, G.L.; Meeuwsen, P.V.</p> <p>1997-09-01</p> <p>Developmental testing of the <span class="hlt">primary</span> cleaning station for spent nuclear fuel (SNF) and canisters is reported. A <span class="hlt">primary</span> clean machine will be used to remove the gross sludge from canisters and fuel while maintaining water quality in the downstream process area. To facilitate SNF separation from canisters and minimize the impact to water quality, all canisters will be subjected to mechanical agitation and flushing with the <span class="hlt">Primary</span> Clean Station. The <span class="hlt">Primary</span> Clean Station consists of an outer containment box with an internally mounted, perforated wash basket. A single canister containing up to 14 fuel assemblies will be loaded into the wash basket, the confinement box lid closed, and the wash basket rotated for a fixed cycle time. During this cycle, basin water will be flushed through the wash basket and containment box to remove and entrain the sludge and carry it out of the box. <span class="hlt">Primary</span> cleaning tests were performed to provide information concerning the removal of sludge from the fuel assemblies while in the basin canisters. The testing was also used to determine if additional fuel cleaning is required outside of the fuel canisters. Hydraulic performance and water demand requirements of the cleaning station were also evaluated. Thirty tests are reported in this document. Tests demonstrated that sludge can be dislodged and suspended sufficiently to remove it from the canister. Examination of fuel elements after cleaning suggested that more than 95% of the exposed fuel surfaces were cleaned so that no visual evidence of remained. As a result of testing, recommendations are made for the cleaning cycle. 3 refs., 16 figs., 4 tabs.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1560490','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1560490"><span>Linking <span class="hlt">Primary</span> Care Information <span class="hlt">Systems</span> and Public Health Vertical Programs in the Philippines: An Open-source Experience</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Tolentino, Herman; Marcelo, Alvin; Marcelo, Portia; Maramba, Inocencio</p> <p>2005-01-01</p> <p>Community-based <span class="hlt">primary</span> care information <span class="hlt">systems</span> are one of the building blocks for national health information <span class="hlt">systems</span>. In the Philippines, after the devolution of health care to local governments, we observed “health information <span class="hlt">system</span> islands” connected to national vertical programs being implemented in devolved health units. These structures lead to a huge amount of “information work” in the transformation of health information at the community level. This paper describes work done to develop and implement the open-source Community Based Health Information Tracking <span class="hlt">System</span> (CHITS) Project, which was implemented to address this information management problem and its outcomes. Several lessons learned from the field as well as software development strategies are highlighted in building community level information <span class="hlt">systems</span> that link to national level health information <span class="hlt">systems</span>. PMID:16779052</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016JMiMi..26h4007B','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016JMiMi..26h4007B"><span>Characterization of a smartphone size haptic rendering <span class="hlt">system</span> based on thin-film <span class="hlt">Al</span>N actuators on glass substrates</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Bernard, F.; Casset, F.; Danel, J. S.; Chappaz, C.; Basrour, S.</p> <p>2016-08-01</p> <p>This paper presents for the first time the characterization of a smartphone-size haptic rendering <span class="hlt">system</span> based on the friction modulation effect. According to previous work and finite element modeling, the homogeneous flexural modes are needed to get the haptic feedback effect. The device studied consists of a thin film <span class="hlt">Al</span>N transducers deposited on an 110  ×  65 mm2 glass substrate. The transducer’s localization on the glass plate allows a transparent central area of 90  ×  49 mm2. Electrical and mechanical parameters of the <span class="hlt">system</span> are extracted from measurement. From this extraction, the electrical impedance matching reduced the applied voltage to 17.5 V AC and the power consumption to 1.53 W at the resonance frequency of the vibrating <span class="hlt">system</span> to reach the haptic rendering specification. Transient characterizations of the actuation highlight a delay under the dynamic tactile detection. The characterization of the <span class="hlt">Al</span>N transducers used as sensors, including the noise rejection, the delay or the output charge amplitude allows detections with high accuracy of any variation due to external influences. Those specifications are the first step to a low-power-consumption feedback-looped <span class="hlt">system</span>.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28125126','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28125126"><span>[Traditional and Complementary Medicine in Brazil: inclusion in the Brazilian Unified National Health <span class="hlt">System</span> and integration with <span class="hlt">primary</span> care].</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Sousa, Islandia Maria Carvalho de; Tesser, Charles Dalcanale</p> <p>2017-01-23</p> <p>This study aimed to analyze the inclusion of Traditional and Complementary Medicine in Brazilian Unified National Health <span class="hlt">System</span> (SUS) and its integration with <span class="hlt">primary</span> healthcare (PHC). A qualitative study drew on institutional data, indexed articles, and case studies in selected Brazilian cities: Campinas (São Paulo State), Florianópolis (Santa Catarina State), Recife (Pernambuco State), Rio de Janeiro, and São Paulo. The analysis adopted the perspective of inclusion of Traditional and Complementary Medicine in the healthcare network and its integration with <span class="hlt">primary</span> healthcare, based on the following dimensions: presence of Traditional and Complementary Medicine on the municipal agenda; position in the services; mode of access to Traditional and Complementary Medicine; Traditional and Complementary Medicine practitioners; types of practices; demand profile; and potential for expansion in the SUS. The authors identified and characterized four types of inclusion and integration of Traditional and Complementary Medicine, whether in association or not: Type 1 - in <span class="hlt">primary</span> healthcare via professionals from the family health teams - Integrated; Type 2 - in <span class="hlt">primary</span> healthcare via professionals with full-time employment - Juxtaposed; Type 3 - in <span class="hlt">primary</span> healthcare via matrix-organized teams - Matrix Organization; Type 4 - in specialized services - Without Integration. The combination of types 1 and 3 was considered a potential guideline for the expansion of Traditional and Complementary Medicine in the SUS and can orient the growth and integration of Traditional and Complementary Medicine with <span class="hlt">primary</span> healthcare. The growing presence of Traditional and Complementary Medicine in the SUS requires conceiving its strategic expansion, while existing experiences should not be wasted.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26262261','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26262261"><span>Development of a Mobile <span class="hlt">System</span> Decision-support for Medical Diagnosis of Asthma in <span class="hlt">Primary</span> Healthcare--InteliMED.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Menezes, Júlio; Gusmão, Cristine</p> <p>2015-01-01</p> <p>The structure of public and <span class="hlt">primary</span> healthcare in Brazil is organized in a way to provide decentralized services. In theory, this scenario could enable the usage of mobile devices integrated with information <span class="hlt">systems</span> of several purposes. In addition, there is a need of decision-support tools that are based on collected evidences, once the professional of <span class="hlt">primary</span> healthcare, which essentially has general knowledge (non-specialist). Therefore there is a need of information that support the decision-making process on more specific contexts. This paper presents the proposal, experience of development and application of the InteliMED, a decision-support <span class="hlt">system</span> to asthma diagnosis of children and adolescents through decision-trees and mobile devices (smartphones and tablets).</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4599053','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4599053"><span>ESHAP chemotherapy is efficient in refractory/relapsed <span class="hlt">primary</span> central nervous <span class="hlt">system</span> lymphoma: report of four cases</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Ungur, Rodica; Tempescul, Adrian; Berthou, Christian; Bagacean, Cristina; Radeanu, Doinel; Muresan, Adriana; Zdrenghea, Mihnea</p> <p>2015-01-01</p> <p><span class="hlt">Primary</span> central nervous <span class="hlt">system</span> non-Hodgkin’s lymphoma is a rare presentation, almost always of diffuse large B-cell type. Although there is no consensus regarding therapy for this condition, induction regimens are based on high-dose methotrexate and consolidation whole-brain radiotherapy, or, more preferred recently, blood–brain barrier penetrating drugs such as etoposide, cytarabine, and alkylating agents like temozolomide, ifosfamide, and lomustine. We present here four cases of relapsed/refractory <span class="hlt">primary</span> central nervous <span class="hlt">system</span> lymphoma treated with ESHAP (etoposide, solumedrol, high-dose cytarabine, and platinum) chemotherapy to complete remission, with the eligible patients proceeding to autologous transplantation. We want to draw attention to this interesting, relatively well tolerated, underused therapeutic option, in a setting where treatment options are scarce and evidence-based recommendations are lacking. PMID:26491351</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://medlineplus.gov/ency/article/000734.htm','NIH-MEDLINEPLUS'); return false;" href="https://medlineplus.gov/ency/article/000734.htm"><span><span class="hlt">Primary</span> lymphoma of the brain</span></a></p> <p><a target="_blank" href="http://medlineplus.gov/">MedlinePlus</a></p> <p></p> <p></p> <p>Brain lymphoma; Cerebral lymphoma; <span class="hlt">Primary</span> lymphoma of the central nervous <span class="hlt">system</span>; Lymphoma - brain ... The cause of <span class="hlt">primary</span> brain lymphoma is not known. People with a weakened immune <span class="hlt">system</span> are at high risk for <span class="hlt">primary</span> lymphoma of the brain. ...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.alsa.org/','NIH-MEDLINEPLUS'); return false;" href="http://www.alsa.org/"><span><span class="hlt">ALS</span> Association</span></a></p> <p><a target="_blank" href="http://medlineplus.gov/">MedlinePlus</a></p> <p></p> <p></p> <p>... toward a world without <span class="hlt">ALS</span>! Walk to Defeat ALS® Walk to Defeat ALS® draws people of all ... We need your help. I Will Advocate National <span class="hlt">ALS</span> Registry The National <span class="hlt">ALS</span> Registry is a congressionally ...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28152659','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28152659"><span>Development of <span class="hlt">primary</span> central nervous <span class="hlt">system</span> lymphoma in a <span class="hlt">systemic</span> lupus erythematosus patient after treatment with mycophenolate mofetil and review of the literature.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Balci, M A; Pamuk, G E; Unlu, E; Usta, U; Pamuk, O N</p> <p>2017-01-01</p> <p><span class="hlt">Primary</span> central nervous <span class="hlt">system</span> lymphoma (PCNSL) is a rare form of extranodal non-Hodgkin lymphoma and four cases of PCNSL have previously been described in association with mycophenolate mofetil. We report the fifth case of PCNSL in a patient with lupus nephropathy while on mycophenolate mofetil treatment.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3495844','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3495844"><span><span class="hlt">AL</span> Amyloidosis</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p></p> <p>2012-01-01</p> <p>Definition of the disease <span class="hlt">AL</span> amyloidosis results from extra-cellular deposition of fibril-forming monoclonal immunoglobulin (Ig) light chains (LC) (most commonly of lambda isotype) usually secreted by a small plasma cell clone. Most patients have evidence of isolated monoclonal gammopathy or smoldering myeloma, and the occurrence of <span class="hlt">AL</span> amyloidosis in patients with symptomatic multiple myeloma or other B-cell lymphoproliferative disorders is unusual. The key event in the development of <span class="hlt">AL</span> amyloidosis is the change in the secondary or tertiary structure of an abnormal monoclonal LC, which results in instable conformation. This conformational change is responsible for abnormal folding of the LC, rich in β leaves, which assemble into monomers that stack together to form amyloid fibrils. Epidemiology <span class="hlt">AL</span> amyloidosis is the most common type of <span class="hlt">systemic</span> amyloidois in developed countries with an estimated incidence of 9 cases/million inhabitant/year. The average age of diagnosed patients is 65 years and less than 10% of patients are under 50. Clinical description The clinical presentation is protean, because of the wide number of tissues or organs that may be affected. The most common presenting symptoms are asthenia and dyspnoea, which are poorly specific and may account for delayed diagnosis. Renal manifestations are the most frequent, affecting two thirds of patients at presentation. They are characterized by heavy proteinuria, with nephrotic syndrome and impaired renal function in half of the patients. Heart involvement, which is present at diagnosis in more than 50% of patients, leading to restrictive cardiopathy, is the most serious complication and engages prognosis. Diagnostic methods The diagnosis relies on pathological examination of an involved site showing Congo red-positive amyloid deposits, with typical apple-green birefringence under polarized light, that stain positive with an anti-LC antibody by immunohistochemistry and/or immunofluorescence. Due to the</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27164089','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27164089"><span>Gene Mutation Profiles in <span class="hlt">Primary</span> Diffuse Large B Cell Lymphoma of Central Nervous <span class="hlt">System</span>: Next Generation Sequencing Analyses.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Todorovic Balint, Milena; Jelicic, Jelena; Mihaljevic, Biljana; Kostic, Jelena; Stanic, Bojana; Balint, Bela; Pejanovic, Nadja; Lucic, Bojana; Tosic, Natasa; Marjanovic, Irena; Stojiljkovic, Maja; Karan-Djurasevic, Teodora; Perisic, Ognjen; Rakocevic, Goran; Popovic, Milos; Raicevic, Sava; Bila, Jelena; Antic, Darko; Andjelic, Bosko; Pavlovic, Sonja</p> <p>2016-05-06</p> <p>The existence of a potential <span class="hlt">primary</span> central nervous <span class="hlt">system</span> lymphoma-specific genomic signature that differs from the <span class="hlt">systemic</span> form of diffuse large B cell lymphoma (DLBCL) has been suggested, but is still controversial. We investigated 19 patients with <span class="hlt">primary</span> DLBCL of central nervous <span class="hlt">system</span> (DLBCL CNS) using the TruSeq Amplicon Cancer Panel (TSACP) for 48 cancer-related genes. Next generation sequencing (NGS) analyses have revealed that over 80% of potentially protein-changing mutations were located in eight genes (CTNNB1, PIK3CA, PTEN, ATM, KRAS, PTPN11, TP53 and JAK3), pointing to the potential role of these genes in lymphomagenesis. TP53 was the only gene harboring mutations in all 19 patients. In addition, the presence of mutated TP53 and ATM genes correlated with a higher total number of mutations in other analyzed genes. Furthermore, the presence of mutated ATM correlated with poorer event-free survival (EFS) (p = 0.036). The presence of the mutated SMO gene correlated with earlier disease relapse (p = 0.023), inferior event-free survival (p = 0.011) and overall survival (OS) (p = 0.017), while mutations in the PTEN gene were associated with inferior OS (p = 0.048). Our findings suggest that the TP53 and ATM genes could be involved in the molecular pathophysiology of <span class="hlt">primary</span> DLBCL CNS, whereas mutations in the PTEN and SMO genes could affect survival regardless of the initial treatment approach.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4881509','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4881509"><span>Gene Mutation Profiles in <span class="hlt">Primary</span> Diffuse Large B Cell Lymphoma of Central Nervous <span class="hlt">System</span>: Next Generation Sequencing Analyses</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Todorovic Balint, Milena; Jelicic, Jelena; Mihaljevic, Biljana; Kostic, Jelena; Stanic, Bojana; Balint, Bela; Pejanovic, Nadja; Lucic, Bojana; Tosic, Natasa; Marjanovic, Irena; Stojiljkovic, Maja; Karan-Djurasevic, Teodora; Perisic, Ognjen; Rakocevic, Goran; Popovic, Milos; Raicevic, Sava; Bila, Jelena; Antic, Darko; Andjelic, Bosko; Pavlovic, Sonja</p> <p>2016-01-01</p> <p>The existence of a potential <span class="hlt">primary</span> central nervous <span class="hlt">system</span> lymphoma-specific genomic signature that differs from the <span class="hlt">systemic</span> form of diffuse large B cell lymphoma (DLBCL) has been suggested, but is still controversial. We investigated 19 patients with <span class="hlt">primary</span> DLBCL of central nervous <span class="hlt">system</span> (DLBCL CNS) using the TruSeq Amplicon Cancer Panel (TSACP) for 48 cancer-related genes. Next generation sequencing (NGS) analyses have revealed that over 80% of potentially protein-changing mutations were located in eight genes (CTNNB1, PIK3CA, PTEN, ATM, KRAS, PTPN11, TP53 and JAK3), pointing to the potential role of these genes in lymphomagenesis. TP53 was the only gene harboring mutations in all 19 patients. In addition, the presence of mutated TP53 and ATM genes correlated with a higher total number of mutations in other analyzed genes. Furthermore, the presence of mutated ATM correlated with poorer event-free survival (EFS) (p = 0.036). The presence of the mutated SMO gene correlated with earlier disease relapse (p = 0.023), inferior event-free survival (p = 0.011) and overall survival (OS) (p = 0.017), while mutations in the PTEN gene were associated with inferior OS (p = 0.048). Our findings suggest that the TP53 and ATM genes could be involved in the molecular pathophysiology of <span class="hlt">primary</span> DLBCL CNS, whereas mutations in the PTEN and SMO genes could affect survival regardless of the initial treatment approach. PMID:27164089</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.osti.gov/scitech/servlets/purl/10159090','SCIGOV-STC'); return false;" href="http://www.osti.gov/scitech/servlets/purl/10159090"><span>A station blackout simulation for the Advanced Neutron Source Reactor using the integrated <span class="hlt">primary</span> and secondary <span class="hlt">system</span> model</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Schneider, E.A.</p> <p>1994-06-01</p> <p>The Advanced Neutron Source Reactor (ANSR) is a research reactor to be built at Oak Ridge National Laboratory. This paper deals with thermal-hydraulic analysis of ANSR`s cooling <span class="hlt">systems</span> during nominal and transient conditions, with the major effort focusing upon the construction and testing of computer models of the reactor`s <span class="hlt">primary</span>, secondary and reflector vessel cooling <span class="hlt">systems</span>. The code RELAP5 was used to simulate transients, such as loss of coolant accidents and loss of off-site power, as well as to model the behavior of the reactor in steady state. Three stages are involved in constructing and using a RELAP5 model: (1) construction and encoding of the desired model, (2) testing and adjustment of the model until a satisfactory steady state is achieved, and (3) running actual transients using the steady-state results obtained earlier as initial conditions. By use of the ANSR design specifications, a model of the reactor`s <span class="hlt">primary</span> and secondary cooling <span class="hlt">systems</span> has been constructed to run a transient simulating a loss of off-site power. This incident assumes a pump coastdown in both the <span class="hlt">primary</span> and secondary loops. The results determine whether the reactor can survive the transition from forced convection to natural circulation.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/20877975','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/20877975"><span>Do the origins of <span class="hlt">primary</span> teeth affect the bond strength of a self-etching adhesive <span class="hlt">system</span> to dentin?</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Bengtson, Camilla Regina Galvão; Bengtson, Antonio Lucindo; Bengtson, Nadya Galvão; Turbino, Miriam Lacalle</p> <p>2010-01-01</p> <p>The aim of this in vitro study was to evaluate the tensile bond strength of a self-etching adhesive <span class="hlt">system</span> to three different dentinal substrates. <span class="hlt">Primary</span> molar teeth that had been recently exfoliated (RE), with unknown time of exfoliation (UT), and extracted due to prolonged retention (PR) were used for this investigation. Ten <span class="hlt">primary</span> molar teeth of each group were cut in the middle following the mesio-distal direction, creating a total of twenty specimens per group. The specimens were included in acrylic resin and had a flat dentin surface exposed. The self-etching adhesive <span class="hlt">system</span> was applied to this surface and a 3-millimeter high cone with diameter of 2 mm in the adhesion area was constructed using composite resin. The specimens were stored in distilled water at 37ºC for 24 hours. Fifteen specimens of each substrate were used for the tensile bond test (n = 15) and 5 had the interface analyzed by scanning electron microscopy (SEM). The data was examined by one-way ANOVA and presented no significant differences between groups (p = 0.5787). The mean values obtained for RE, UT and PR were 18.39 ± 9.70, 19.41 ± 7.80, and 23.30 ± 9.37 MPa, respectively. Any dentinal substrates of <span class="hlt">primary</span> teeth studied are safe for tensile bond strength tests with adhesive <span class="hlt">systems</span>.</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li><a href="#" onclick='return showDiv("page_22");'>22</a></li> <li><a href="#" onclick='return showDiv("page_23");'>23</a></li> <li><a href="#" onclick='return showDiv("page_24");'>24</a></li> <li class="active"><span>25</span></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_25 --> <center> <div class="footer-extlink text-muted"><small>Some links on this page may take you to non-federal websites. 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