Science.gov

Sample records for prix observes sur

  1. Old Fire/Grand Prix Fire, California

    NASA Technical Reports Server (NTRS)

    2003-01-01

    On November 18, 2003, the Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) on NASA's Terra satellite acquired this image of the Old Fire/Grand Prix fire east of Los Angeles. The image is being processed by NASA's Wildfire Response Team and will be sent to the United States Department of Agriculture's Forest Service Remote Sensing Applications Center (RSAC) which provides interpretation services to Burned Area Emergency Response (BAER) teams to assist in mapping the severity of the burned areas. The image combines data from the visible and infrared wavelength regions to highlight the burned areas.

    With its 14 spectral bands from the visible to the thermal infrared wavelength region, and its high spatial resolution of 15 to 90 meters (about 50 to 300 feet), ASTER images Earth to map and monitor the changing surface of our planet.

    ASTER is one of five Earth-observing instruments launched December 18, 1999, on NASA's Terra satellite. The instrument was built by Japan's Ministry of Economy, Trade and Industry. A joint U.S./Japan science team is responsible for validation and calibration of the instrument and the data products.

    The broad spectral coverage and high spectral resolution of ASTER provides scientists in numerous disciplines with critical information for surface mapping, and monitoring of dynamic conditions and temporal change. Example applications are: monitoring glacial advances and retreats; monitoring potentially active volcanoes; identifying crop stress; determining cloud morphology and physical properties; wetlands evaluation; thermal pollution monitoring; coral reef degradation; surface temperature mapping of soils and geology; and measuring surface heat balance.

    Michael Abrams at NASA's Jet Propulsion Laboratory (JPL), Pasadena, Calif., is the U.S. science team leader; Bjorn Eng of JPL is the project manager. The Terra mission is part of NASA's Earth Science Enterprise, a long- term research effort dedicated to

  2. Alt-Energy Grand Prix Inspires an "I Can" Attitude

    ERIC Educational Resources Information Center

    Tessmer, Al; Trzeciak, Mark

    2010-01-01

    This article describes how a team comprised largely of high school students builds and races an E85-fueled car and takes first place at the Bowling Green (Ohio) State University (BGSU) Grand Prix. Free and open to the public, the event features student drivers and crews, racing go-karts powered by renewable, ethanol-based E85 fuel. The track is a…

  3. 75 FR 20920 - Safety Zone; Lake Havasu Grand Prix, Lake Havasu, AZ

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-22

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone; Lake Havasu Grand Prix, Lake Havasu, AZ... temporary safety zone upon the navigable waters of Lake Havasu on the Colorado River in Lake Havasu City, Arizona for the Lake Havasu Grand Prix. This temporary safety zone is necessary to provide for the...

  4. Television Experience Patterns in Children and Juveniles; Illustrated by the Prize-Winning Programmes of the Prix Jeunesse 1964. Research Report. Publications of the International Central Institute for Youth and Educational Television. No.1.

    ERIC Educational Resources Information Center

    Keilhacker, Margarete; Vogg, Gunther

    A study to test the appeal, reception, and response quality in the case of programs screened at the 1st. Prix Jeunesse contest in Munich by the observation of children and juveniles (age-grouped 6 to 12, 12 to 15, and 15 and over) is described in this paper. Specific questions considered are: 1. What conditions govern appeal? 2. Are age and sex…

  5. Stride characteristics of horses competing in Grand Prix jumping.

    PubMed

    Leach, D H; Ormrod, K; Clayton, H M

    1984-05-01

    An investigation was made of the stride characteristics of horses jumping 2 obstacles during a Grand Prix competition. One obstacle was a picket fence and rail 1.3 m high (fence 2), and the other was a coop and rail 1.52 m high (fence 11). Thirteen distance and 22 timing measurements of 17 horses were extracted from high-speed films, using computer-aided analysis. These data were used to compare takeoff and landing of the lead and nonlead legs, the thoracic limbs and pelvic limbs, and fence 2 and fence 11. Paired t-tests were used to compare means and a stepwise regression analysis was done for each fence, using the total horizontal distance jumped as the dependent variable. Stride timing and distance measurements did not differ (P less than 0.05) between the 2 fences . Each horse approached the fences in a moderately fast canter and, at takeoff , placed the nonlead thoracic limb earlier and farther from the fence than the lead thoracic limb (P less than 0.05). The nonlead leg stance phase lasted longer than the lead leg stance phase (P less than 0.05). The lead and nonlead pelvic limbs acted more in unison than the thoracic limbs and did not differ in their time of placement, stance phase duration, or position from the fence (P less than 0.05). The overlap of the stance phases of the pelvic limbs was greater than that of the thoracic limbs (P less than 0.05).(ABSTRACT TRUNCATED AT 250 WORDS) PMID:6732020

  6. 78 FR 34568 - Special Local Regulation; Heritage Coast Offshore Grand Prix, Tawas Bay; East Tawas, MI

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-10

    .... SUPPLEMENTARY INFORMATION: Table of Acronyms DHS Department of Homeland Security FR Federal Register NPRM Notice... SECURITY Coast Guard 33 CFR Part 100 RIN 1625-AA08 Special Local Regulation; Heritage Coast Offshore Grand... immediately after the Heritage Coast Offshore Grand Prix boat race. This special local regulation...

  7. 78 FR 28164 - Special Local Regulation; Aguada Offshore Grand Prix, Bahia de Aguadilla; Aguada, PR

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-14

    .... SUPPLEMENTARY INFORMATION: Table of Acronyms DHS Department of Homeland Security FR Federal Register NPRM Notice... public dockets in the January 17, 2008, issue of the Federal Register (73, FR 3316). 4. Public Meeting We... in Aguada, Puerto Rico during the Aguada Offshore Grand Prix, a high speed boat race. The event...

  8. 75 FR 34932 - Safety Zone; Michigan City Super Boat Grand Prix, Lake Michigan, Michigan City, IN

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-21

    ... Super Boat Grand Prix, Lake Michigan, Michigan City, IN in the Federal Register (75 FR 22333). We... intended to restrict vessels from a portion of Lake Michigan due to a high speed boat racing event. This... associated with a high speed boat racing event. DATES: This regulation is effective from 9 a.m. until 4...

  9. 76 FR 29642 - Special Local Regulations; Miami Super Boat Grand Prix, Miami Beach, FL

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-23

    ... establishing special local regulations on the waters of the Atlantic Ocean east of ] Miami Beach, Florida... will be held on the waters of the Atlantic Ocean east of Miami Beach, Florida. Approximately 25 high... Atlantic Ocean east of Miami Beach, Florida during the Miami Super Boat Grand Prix. The special...

  10. 33 CFR 100.106 - Freeport Grand Prix, Long Beach, NY.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Freeport Grand Prix, Long Beach... Beach, NY. (a) Regulated area. The regulated area is a trapezoidal area on the coastal Atlantic waters of Long Island to the south of Long Beach, New York. The regulated area is one and one quarter...

  11. 33 CFR 100.106 - Freeport Grand Prix, Long Beach, NY.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 1 2011-07-01 2011-07-01 false Freeport Grand Prix, Long Beach... Beach, NY. (a) Regulated area. The regulated area is a trapezoidal area on the coastal Atlantic waters of Long Island to the south of Long Beach, New York. The regulated area is one and one quarter...

  12. 75 FR 21194 - Special Local Regulation; Harrison Township Grand Prix, Lake St. Clair; Harrison Township, MI

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-23

    ... Federal Register (73 FR 3316). Public Meeting We do not now plan to hold a public meeting. But you may... SECURITY Coast Guard 33 CFR Part 100 RIN 1625-AA08 Special Local Regulation; Harrison Township Grand Prix, Lake St. Clair; Harrison Township, MI AGENCY: Coast Guard, DHS. ACTION: Notice of proposed...

  13. 75 FR 39445 - Special Local Regulation; Harrison Township Grand Prix, Lake St. Clair, Harrison Township, MI

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-09

    ... St. Clair, Harrison Township, MI in the Federal Register (75 FR 21194). We received zero comments on... SECURITY Coast Guard 33 CFR Part 100 RIN 1625-AA08 Special Local Regulation; Harrison Township Grand Prix, Lake St. Clair, Harrison Township, MI AGENCY: Coast Guard, DHS. ACTION: Temporary final rule....

  14. Considérations nosographiques sur le délire d'infestation parasitaire à travers trois observations cliniques

    PubMed Central

    Berhili, Nabil; Bout, Amine; Hlal, Hayat; Aarab, Chadya; Aalouane, Rachid; Rammouz, Ismail

    2016-01-01

    Le syndrome d'Ekbom, ou délire d'infestation parasitaire, est une pathologie rare, caractérisée par la conviction inébranlable d'avoir une peau infestée d'insectes ou de parasites. Il s'agit d'un délire monothématique à mécanisme hallucinatoire qui touche typiquement les femmes d’âge avancé. Nous rapportons les cas de trois patients qui présentent un délire d'infestation parasitaire dans des contextes cliniques différents. Le premier patient souffre d'un délire d'infestation isolé correspondant à la forme décrite par Karl Ekbom. Le deuxième cas présente un délire d'infestation secondaire, s'inscrivant dans le cadre d'une leuco-encéphalopathie de type CADASIL. Enfin, le troisième patient se présente dans un tableau évocateur d'un épisode dépressif avec une caractéristique psychotique qui intègre le délire d'infestation. Ces trois vignettes cliniques illustrent parfaitement le caractère trans-nosographique de ce syndrome ainsi que les difficultés de prise en charge de ces patients, tant au niveau de l'alliance thérapeutique que sur le plan des choix en matière de traitement pharmacologiques. PMID:27642468

  15. 77 FR 47522 - Special Local Regulation; Port Huron Offshore Gran Prix, St. Clair River; Port Huron, MI

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-09

    ... Department of Homeland Security FR Federal Register NPRM Notice of Proposed Rulemaking ] A. Regulatory... SECURITY Coast Guard 33 CFR Part 100 RIN 1625-AA08 Special Local Regulation; Port Huron Offshore Gran Prix, St. Clair River; Port Huron, MI AGENCY: Coast Guard, DHS. ACTION: Temporary final rule. SUMMARY:...

  16. 77 FR 15600 - Special Local Regulation; Emerald Coast Super Boat Grand Prix; Saint Andrew Bay; Panama City, FL

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-16

    ... SECURITY Coast Guard 33 CFR Part 100 RIN 1625-AA08 Special Local Regulation; Emerald Coast Super Boat Grand... crews, vessels, and persons on navigable waters during the Emerald Coast Super Boat Grand Prix high... received an application for a Marine Event Permit on January 31, 2011 from Super Boat International,...

  17. 78 FR 25574 - Special Local Regulations; Third Annual Space Coast Super Boat Grand Prix, Atlantic Ocean; Cocoa...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-02

    ...) 366-9826. SUPPLEMENTARY INFORMATION: Table of Acronyms DHS Department of Homeland Security FR Federal... Ocean east of Cocoa Beach, Florida during the Space Coast Super Boat Grand Prix, a series of high-speed... approximately 30 high-speed race boats are anticipated to participate in the races, and approximately...

  18. 77 FR 15006 - Special Local Regulations; Third Annual Space Coast Super Boat Grand Prix, Atlantic Ocean, Cocoa...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-14

    ... Super Boat Grand Prix, Atlantic Ocean, Cocoa Beach, FL AGENCY: Coast Guard, DHS. ACTION: Notice of... of the Atlantic Ocean east of Cocoa Beach, Florida during the Third Annual Space Coast Super Boat...-speed boat races. The event will be held on the waters of the Atlantic Ocean east of Cocoa...

  19. 76 FR 26931 - Safety Zone; Second Annual Space Coast Super Boat Grand Prix, Atlantic Ocean, Cocoa Beach, FL

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-10

    ... Prix, Atlantic Ocean, Cocoa Beach, FL AGENCY: Coast Guard, DHS. ACTION: Temporary final rule. SUMMARY: The Coast Guard is establishing a temporary safety zone on the waters of the Atlantic Ocean east of... will be held on the waters of the Atlantic Ocean east of Cocoa Beach, Florida. Approximately 30...

  20. Les torsions sur testicules cryptorchides

    PubMed Central

    Gharbi, Mohamed; Amri, Najmeddine; Chambeh, Wahib; Braiek, Salem; Kamel, Rafik El

    2010-01-01

    Résumé But : La cryptorchidie est une pathologie assez fréquente en urologie. Elle est associée à un risque élevé d’infertilité et de dégénérescence. Elle semble aussi être associée à un risque important de torsion. Cette entité est très peu abordée dans la littérature. Nous rapportons tous les cas de torsion sur testicule cryptorchide observés à notre service dans le but de mieux caractériser cette pathologie et de réduire ainsi le taux d’orchidectomies. Méthodologie : Il s’agit d’une étude rétrospective portant sur tous les cas de torsion sur testicule cryptorchide opérés dans notre service d’urologie entre 1999 et 2007. Les patients ont fait l’objet d’une description basée sur le résumé de leurs observations. Résultats : Les patients étaient âgés de 7 mois à 39 ans. La torsion touchait le testicule droit dans 53 % des cas. Le tableau clinique comportait une douleur au niveau de la région inguinale d’apparition soudaine avec une masse sous-cutanée inflammatoire et douloureuse à ce niveau et surtout un hémiscrotum homolatéral vide. Dans 60 % des cas, le diagnostic était tardif et une orchidectomie a été réalisée. Dans les autre cas, un abaissement du testicule a été réalisé avec orchidopexie controlatéral dans le même temps opératoire. Conclusion : Bien qu’il s’agisse d’une pathologie peu courante, la torsion sur testicule cryptorchide doit être étudiée davantage. Le diagnostic précoce permettra de sauver et d’abaisser le testicule et faciliter ainsi le dépistage d’une éventuelle dégénérescence. PMID:21191497

  1. Observation directe de la croissance d'hydrosilicate de calcium sur des surfaces d'alité et de silice par microscopie à force atomique

    NASA Astrophysics Data System (ADS)

    Gauffinet, Sandrine; Finot, Éric; Lesniewska, Eric; Nonat, André

    1998-08-01

    Direct observation of the growth of calcium silicate hydrates, the tricalcium silicate hydration products, at the solid-solution interface were performed by atomic force microscopy. The covering of the surface of alite or silica by a three-dimensional oriented aggregation of nano particles of calcium silicate hydrate is always observed whatever the sample. All observations and quantifications made on calcium silicate growth at the submicronic level are in agreement with the data deduced from the study of the system evolution at the macroscopic level.

  2. Pockmarks off Big Sur, California

    USGS Publications Warehouse

    Paull, C.; Ussler, W.; Maher, N.; Greene, H. Gary; Rehder, G.; Lorenson, T.; Lee, H.

    2002-01-01

    A pockmark field was discovered during EM-300 multi-beam bathymetric surveys on the lower continental slope off the Big Sur coast of California. The field contains ??? 1500 pockmarks which are between 130 and 260 m in diameter, and typically are 8-12 m deep located within a 560 km2 area. To investigate the origin of these features, piston cores were collected from both the interior and the flanks of the pockmarks, and remotely operated vehicle observation (ROV) video and sampling transects were conducted which passed through 19 of the pockmarks. The water column within and above the pockmarks was sampled for methane concentration. Piston cores and ROV collected push cores show that the pockmark field is composed of monotonous fine silts and clays and the cores within the pockmarks are indistinguishable from those outside the pockmarks. No evidence for either sediment winnowing or diagenetic alteration suggestive of fluid venting was obtained. 14C measurements of the organic carbon in the sediments indicate continuous sedimentation throughout the time resolution of the radiocarbon technique ( ??? 45000 yr BP), with a sedimentation rate of ??? 10 cm per 1000 yr both within and between the pockmarks. Concentrations of methane, dissolved inorganic carbon, sulfate, chloride, and ammonium in pore water extracted from within the cores are generally similar in composition to seawater and show little change with depth, suggesting low biogeochemical activity. These pore water chemical gradients indicate that neither significant accumulations of gas are likely to exist in the shallow subsurface ( ??? 100 m) nor is active fluid advection occurring within the sampled sediments. Taken together the data indicate that these pockmarks are more than 45000 yr old, are presently inactive, and contain no indications of earlier fluid or gas venting events. ?? 2002 Elsevier Science B.V. All rights reserved.

  3. Endothelial SUR-8 Acts in an ERK-Independent Pathway During Atrioventricular Cushion Development

    PubMed Central

    Yi, Jing; Chen, Muyun; Wu, Xiaohui; Yang, Xiao; Xu, Tian; Zhuang, Yuan; Han, Min; Xu, Rener

    2010-01-01

    SUR-8, a conserved leucine-rich repeats protein, was first identified as a positive regulator of Ras pathway in Caenorhabditis elegans. Biochemical studies indicated that SUR-8 interacts with Ras and Raf, leading to the elevated ERK activity. However, the physiological role of SUR-8 during mammalian development remains unclear. Here we found that germline deletion of SUR-8 in mice resulted in early embryonic lethality. Inactivated SUR-8 specifically in mouse endothelial cells (ECs) revealed that SUR-8 is essential for embryonic heart development. SUR-8 deficiency in ECs resulted in late embryonic lethality, and the mutant mice displayed multiple cardiac defects. The reduced endothelial-mesenchymal transformation (EMT) and the reduced mesenchyme proliferation phase were observed in the atrioventricular canal (AVC) within the mutant hearts, leading to the formation of hypoplastic endocardial cushions. However, ERK activation did not appear to be affected in mutant ECs, suggesting that SUR-8 may act in an ERK-independent pathway to regulate AVC development. Developmental Dynamics 239:2005–2013, 2010 © 2010 Wiley-Liss, Inc. PMID:20549726

  4. La tuberculose cutanée: observation de six cas confirmés au CHU Souro SANOU (CHUSS) de Bobo-Dioulasso (Burkina Faso)

    PubMed Central

    Andonaba, Jean Baptiste; Barro-Traoré, Fatou; Yaméogo, Téné; Diallo, Boukary; Korsaga-Somé, Nina; Traoré, Adama

    2013-01-01

    La localisation cutanée de la maladie tuberculeuse demeure une forme rare et représente seulement 2,1% des localisations. L'objet de cette étude est de rapporter le profil épidémiologique, anatomoclinique et évolutif des cas de tuberculose ganglio-cutanée diagnostiqués dans un CHU au Burkina Faso. La fréquence de la tuberculose cutanée est très faible au CHUSS. Six cas ont été diagnostiqués entre 2004 et 2010, soit une fréquence de un cas par an. La durée d’évolution des cas allait de deux jusqu’à dix ans avant leur diagnostic. Les lésions observées étaient: trois scrofulodermes, trois gommes, une tuberculose testiculaire associée à un mal de Pott, un cas de polyadénopathies et des cicatrices atropho-rétractiles dans la plupart des cas. Sur le plan anatomopathologique, des granulomes tuberculoïdes ont été mis en évidence dans tous les cas avec une forte réaction tuberculinique à l'IDR. Sous antituberculeux pendant six mois, l’évolution a été bonne dans tous les cas mais au prix de séquelles cutanées cicatricielles inesthétiques. Son ampleur reste peut-être encore méconnue. Le renforcement du plateau technique du CHU et une bonne collaboration interdisciplinaire contribuerait à un meilleur diagnostic et prise en charge de cette affection. PMID:24648863

  5. AirMSPI PODEX BigSur Terrain Images

    Atmospheric Science Data Center

    2013-12-13

    ... from the PODEX 2013 Campaign   Big Sur target (Big Sur, California) 02/03/2013 Terrain-projected   Select ...   Version number   For more information, see the Data Product Specifications (DPS)   ...

  6. Fires Burning near Big Sur, California

    NASA Technical Reports Server (NTRS)

    2008-01-01

    Fires near Big Sur, Calif., continued to burn unchecked when the Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) instrument on NASA's Terra satellite captured this image on Sunday, June 29. In Northern California alone, fires have consumed more than 346,000 acres.At least 18,000 people have deployed to attempt to extinguish or control the flames. Air quality as far away as San Francisco has been adversely impacted by the dense clouds of smoke and ash blowing towards the northwest. The satellite image combines a natural color portrayal of the landscape with thermal infrared data showing the active burning areas in red. The dark area in the lower right is a previous forest fire.

    ASTER is one of five Earth-observing instruments launched December 18, 1999, on NASA's Terra satellite. The instrument was built by Japan's Ministry of Economy, Trade and Industry. A joint U.S./Japan science team is responsible for validation and calibration of the instrument and the data products.

    The broad spectral coverage and high spectral resolution of ASTER provides scientists in numerous disciplines with critical information for surface mapping, and monitoring of dynamic conditions and temporal change. Example applications are: monitoring glacial advances and retreats; monitoring potentially active volcanoes; identifying crop stress; determining cloud morphology and physical properties; wetlands evaluation; thermal pollution monitoring; coral reef degradation; surface temperature mapping of soils and geology; and measuring surface heat balance.

    The U.S. science team is located at NASA's Jet Propulsion Laboratory, Pasadena, Calif. The Terra mission is part of NASA's Science Mission Directorate.

    Size: 35.4 by 57 kilometers (21.9 by 34.2 miles) Location: 36.1 degrees North latitude, 121.6 degrees West longitude Orientation: North at top Image Data: ASTER bands 3, 2, and 1 Original Data Resolution: 15 meters (49 feet) Dates Acquired: June 29

  7. Patrik and Putrik and Clown Ferdl; Findings and Cognition on the Television Perception of Children and Young People Based on the Prize-Winning Programmes of Prix Jeunesse 1966. Publications of the Internationales Zentralinstitut fur das Jugend- und Bildungsfernsehen, Number 3.

    ERIC Educational Resources Information Center

    Griebel, Francine, Ed.; Burger, Anette, Ed.

    The results of an investigation of the reactions of young children (ranging from four to nine years of age) in France, Germany, England, America, and Czechoslovkia to two Prix Jeunesse winning television films are examined in this document. Summarized reports from each of the participating countries for the film "Patrik and Putrik" and,…

  8. Sur8 mediates tumorigenesis and metastasis in colorectal cancer

    PubMed Central

    Lee, Young-Mi; Kaduwal, Saluja; Lee, Kug Hwa; Park, Jong-Chan; Jeong, Woo-Jeong; Choi, Kang-Yell

    2016-01-01

    Sur8, a scaffold protein of the Ras pathway, interacts with Ras and Raf and modulates the Ras-extracellular signal-regulated kinase (ERK) pathway. Here we show that Sur8 is overexpressed in established human colorectal cancer (CRC) cell lines and CRC patient tissues. Moreover, Sur8 expression is increased during liver metastasis in CRC patients. Sur8 knockdown decreases ERK and Akt activities in CRC cell lines, regardless of their K-Ras, B-Raf or PI3K mutation status. Overexpression or knockdown of Sur8 increases or decreases, respectively, the proliferation or transformation of CRC cell lines. Sur8 knockdown attenuates the migration and invasion of HCT116 CRC cells. Subcutaneous or orthotopic injection of HCT116 cells harboring a doxycycline (Dox)-mediated Sur8 knockdown system in nude mice resulted in decreased tumorigenic potential and inhibited the liver metastatic potential of HCT116 cells. Taken together, our data support the role of Sur8 as a promoter of tumorigenesis and liver metastasis in CRC through its modulation of the Ras-ERK and PI3K-Akt signaling pathways. PMID:27469030

  9. Sur8 mediates tumorigenesis and metastasis in colorectal cancer.

    PubMed

    Lee, Young-Mi; Kaduwal, Saluja; Lee, Kug Hwa; Park, Jong-Chan; Jeong, Woo-Jeong; Choi, Kang-Yell

    2016-01-01

    Sur8, a scaffold protein of the Ras pathway, interacts with Ras and Raf and modulates the Ras-extracellular signal-regulated kinase (ERK) pathway. Here we show that Sur8 is overexpressed in established human colorectal cancer (CRC) cell lines and CRC patient tissues. Moreover, Sur8 expression is increased during liver metastasis in CRC patients. Sur8 knockdown decreases ERK and Akt activities in CRC cell lines, regardless of their K-Ras, B-Raf or PI3K mutation status. Overexpression or knockdown of Sur8 increases or decreases, respectively, the proliferation or transformation of CRC cell lines. Sur8 knockdown attenuates the migration and invasion of HCT116 CRC cells. Subcutaneous or orthotopic injection of HCT116 cells harboring a doxycycline (Dox)-mediated Sur8 knockdown system in nude mice resulted in decreased tumorigenic potential and inhibited the liver metastatic potential of HCT116 cells. Taken together, our data support the role of Sur8 as a promoter of tumorigenesis and liver metastasis in CRC through its modulation of the Ras-ERK and PI3K-Akt signaling pathways. PMID:27469030

  10. Adolescence et pornographie sur la toile

    PubMed Central

    Haza, Marion

    2012-01-01

    Dans cet article, nous abordons la question de l’accès à la pornographie sur Internet par les adolescents. Nous déclinons plusieurs facettes de ces rencontres: la rencontre «fortuite», quand les adolescents sont confrontés à des images intempestives, des publicités ou spams avec des contenus pornographiques; la rencontre «spectatrice», quand les adolescents cherchent activement des vidéos ou photos mettant en scène la sexualité; et enfin la rencontre «actrice», quand les adolescents se mettent en scène eux-mêmes, seuls ou à plusieurs, de façon pornographique sur le Net. A partir d’exemple, nous réfléchissons aux enjeux de ces rencontres virtuelles précoces de la sexualité adulte par rapport au développement adolescent et à la représentation de leur propre sexualité en construction. PMID:22876261

  11. Le point sur les amas de galaxies

    NASA Astrophysics Data System (ADS)

    Pierre, M.

    galaxies jouent donc un rôle de premier plan dans toute étude cosmologique et par conséquent, sont indispensables à notre compréhension globale de l'univers. Dans l'introduction générale, nous détaillons cet aspect fondamental en montrant comment l'étude des amas peut contribuer à contraindre les scénarios cosmologiques. Une fois le contexte scientifique délimité, les chapitres suivants s'attachent à présenter les diverses propriétés des amas et leur évolution cosmique observée dans diverses longueurs d'onde principalement dans les domaines visible (galaxies), X (gaz) et radio (gaz et particules). Nous verrons que l'étude détaillée d'un amas implique celle de l'interaction entre ses différentes composantes et est un passage obligé pour remonter au paramètre ultime (ou premier) qu'est sa masse. Loin d'être un détour ennuyeux, ceci sera l'occasion d'aborder des phénomènes physiques extrêmement variés tel l'aspect multi-phases du milieu intra-amas, les sursauts de formation d'étoiles et l'évolution morphologique des galaxies capturées par les amas, ou bien encore, l'interaction entre le plasma intra-amas et les particules relativistes accélérées lors de la fusion entre deux amas. Bien sûr, pour chaque longueur d'onde, nous ne manquerons pas de décrire simplement les techniques d'observation et d'analyse mises en oeuvre ; celles-ci sont particulièrement intéressantes dans le cas de l'instrumentation spatiale. Nous terminerons en présentant des projets d'observatoires pour l'horizon 2010 et leur impact prévu sur l'étude des amas de galaxies.

  12. Grossesse sur cicatrice de césarienne: à propos d'un cas et revue de la literature

    PubMed Central

    Lachiri, Boutaina; Zazi, Abdelgheni; Benkerroum, Zineb; Hafidi, Moulay Rachid; Kouach, Jaouad; Rahali, Driss Moussaoui; Dehayni, Mohamed

    2015-01-01

    La grossesse sur cicatrice de césarienne est une forme rare de grossesse ectopique qui engage le pronostic vital et fonctionnel utérin par hémorragie ou par rupture utérine précoce. Nous rapportons le cas d'une grossesse ectopique sur cicatrice de césarienne diagnostiquée à 11 semaines d'aménorrhée suite à une aspiration blanche pour grossesse arrêtée chez une patiente de 43 ans porteuse d'un utérus bi-cicatriciel. A travers cette observation ainsi qu'une revue de la littérature les auteurs vont essayer de mettre le point sur les méthodes diagnostiques et thérapeutiques de cette entité rare afin d'améliorer la prise en charge. PMID:26213603

  13. Lithiase géante sur enterocystoplastie

    PubMed Central

    Elmortaji, Khalid; Elomri, Ghassane; Bennani, Saad; Rabii, Redouane; Aboutaib, Rachid; Meziane, Fethi

    2014-01-01

    La formation des lithiases est une complication fréquente des entérocystoplasties après cystectomie radicale pour tumeur de vessie infiltrante. Le délai d'apparition dépend des facteurs de risque favorisants notamment les infections urinaires. Néanmoins la survenue de lithiase géante sur néovessie reste exceptionnelle, seulement 5 cas ont été rapportés dans la littérature. Nous rapportons dans ce travail, le cas d'une lithiase géante compliquant une entérocystoplastie chez un malade suivi pour tumeur de vessie infiltrante. PMID:25932070

  14. AirMSPI PODEX Big Sur Ellipsoid Images

    Atmospheric Science Data Center

    2013-12-11

    ... AirMSPI Browse Images from the PODEX 2013 Campaign   Big Sur target 02/03/2013 Ellipsoid-projected   Select ...   Version number   For more information, see the  Data Product Specifications (DPS) ...

  15. Lignes directrices canadiennes sur la rhinosinusite chronique

    PubMed Central

    Kaplan, Alan

    2013-01-01

    Résumé Objectif Présenter un résumé clinique des lignes directrices canadiennes sur la rhinosinusite chronique (RSC) qui comporte des recommandations pertinentes aux médecins de famille. Qualité des données Les auteurs des lignes directrices ont effectué une recherche documentaire systématique dans la littérature médicale et ont rédigé une ébauche de recommandations. Une cote a été donnée à la fois en fonction de la fiabilité des données probantes et de la solidité des recommandations. On a sollicité les commentaires d’experts en contenu de l’extérieur, ainsi que l’aval des sociétés médicales (Association pour la microbiologie médicale et l’infectiologie Canada, Société canadienne d’allergie et d’immunologie clinique, Canadian Society of Otolaryngology—Head and Neck Surgery, Association canadienne des médecins d’urgence et Regroupement canadien des médecins de famille en santé respiratoire). Message principal Le diagnostic d’une RSC se fonde sur le type et la durée des symptômes et une constatation objective d’une inflammation de la muqueuse nasale ou des sinus paranasaux. La rhinosinusite chronique est catégorisée en fonction de la présence ou de l’absence de polypes nasaux et cette distinction entraîne des différences dans le traitement. On traite la rhinosinusite chronique avec polypes nasaux au moyen de corticostéroïdes par voie intranasale. Des antibiotiques sont recommandés quand les symptômes indiquent une infection (douleur ou purulence). Pour une RSC sans polypes nasaux, on recommande des corticostéroïdes par voie intranasale et des antibiotiques de deuxième ligne (par ex. combinaisons amoxicilline–acide clavulanique ou fluoroquinolones à activité accrue contre Gram positif). Une irrigation avec une solution saline, des stéroïdes par voie orale et des tests d’allergies pourraient être appropriées. Si le patient ne répond pas au traitement, il faudrait envisager d

  16. Carcinome hépatocellulaire non fibrolamellaire sur foie sain

    PubMed Central

    Bouomrani, Salem; Kilani, Ichrak; Nouma, Hanène; Slama, Alaeddine; Beji, Maher

    2014-01-01

    Le carcinome hépatocellulaire (CHC) survient le plus souvent sur foie de cirrhose. Sa survenue sur un foie sain est exceptionnelle et pose un véritable défit diagnostique pour le clinicien. Nous rapportons l'observation d'un patient de 53 ans, sans antécédents pathologiques notables qui fût admis pour exploration d'une douleur de l'hypochondre droit évoluant depuis quelques mois avec une exacerbation récente, associée à un amaigrissement important et une altération de l’état général. L'examen clinique notait une hépatomégalie ferme et douloureuse. L’échographie abdominale montrait une masse hétérogène du secteur latéral droit du foie faisant 10 cm de grand axe. La TDM abdominale montrait une masse tissulaire, hétérogène, à vascularisation artérielle importante, mesurant 10 cm de diamètre et occupant le secteur latéral droit du foie. Cette tumeur comprime la branche portale droite sans signes d'extension. Il n'y avait pas d'adénopathie ni d’épanchement intra abdominal. La ponction biopsique écho-guidée avait conclu à un CHC non fibrolamellaire. Le bilan biologique, en particulier les transaminases, le taux de prothrombine, l’électrophorèse des protéines sanguine et l'alpha foeto-protéine, était sans anomalies. Les sérologies de l'hépatites virales B et C ainsi que la recherche des auto anticorps spécifiques des hépatites auto immunes et le bilan cuprique étaient aussi négatives. Vue l’âge, le stade avancé de la tumeur et l'altération de l’état général la conduite thérapeutique était de s'abstenir. PMID:25419293

  17. Kir6.2 activation by sulfonylurea receptors: a different mechanism of action for SUR1 and SUR2A subunits via the same residues

    PubMed Central

    Principalli, Maria A; Dupuis, Julien P; Moreau, Christophe J; Vivaudou, Michel; Revilloud, Jean

    2015-01-01

    ATP-sensitive potassium channels (K-ATP channels) play a key role in adjusting the membrane potential to the metabolic state of cells. They result from the unique combination of two proteins: the sulfonylurea receptor (SUR), an ATP-binding cassette (ABC) protein, and the inward rectifier K+ channel Kir6.2. Both subunits associate to form a heterooctamer (4 SUR/4 Kir6.2). SUR modulates channel gating in response to the binding of nucleotides or drugs and Kir6.2 conducts potassium ions. The activity of K-ATP channels varies with their localization. In pancreatic β-cells, SUR1/Kir6.2 channels are partly active at rest while in cardiomyocytes SUR2A/Kir6.2 channels are mostly closed. This divergence of function could be related to differences in the interaction of SUR1 and SUR2A with Kir6.2. Three residues (E1305, I1310, L1313) located in the linker region between transmembrane domain 2 and nucleotide-binding domain 2 of SUR2A were previously found to be involved in the activation pathway linking binding of openers onto SUR2A and channel opening. To determine the role of the equivalent residues in the SUR1 isoform, we designed chimeras between SUR1 and the ABC transporter multidrug resistance-associated protein 1 (MRP1), and used patch clamp recordings on Xenopus oocytes to assess the functionality of SUR1/MRP1 chimeric K-ATP channels. Our results reveal that the same residues in SUR1 and SUR2A are involved in the functional association with Kir6.2, but they display unexpected side-chain specificities which could account for the contrasted properties of pancreatic and cardiac K-ATP channels. PMID:26416970

  18. Random assembly of SUR subunits in K(ATP) channel complexes.

    PubMed

    Cheng, Wayland W L; Tong, Ailing; Flagg, Thomas P; Nichols, Colin G

    2008-01-01

    Sulfonylurea receptors (SURs) associate with Kir6.x subunits to form tetradimeric K(ATP) channel complexes. SUR1 and SUR2 confer differential channel sensitivities to nucleotides and pharmacological agents, and are expressed in specific, but overlapping, tissues. This raises the question of whether these different SUR subtypes can assemble in the same channel complex and generate channels with hybrid properties. To test this, we engineered dimeric constructs of wild type or N160D mutant Kir6.2 fused to SUR1 or SUR2A. Dimeric fusions formed functional, ATP-sensitive, channels. Coexpression of weakly rectifying SUR1-Kir6.2 (WTF-1) with strongly rectifying SUR1-Kir6.2[N160D] (NDF-1) in COSm6 cells results in mixed subunit complexes that exhibit unique rectification properties. Coexpression of NDF-1 and SUR2A-Kir6.2 (WTF-2) results in similar complex rectification, reflecting the presence of SUR1- and SUR2A-containing dimers in the same channel. The data demonstrate clearly that SUR1 and SUR2A subunits associate randomly, and suggest that heteromeric channels will occur in native tissues. PMID:18690055

  19. Finding the SurPriSe: A Case Study of a Faculty Learning Community

    ERIC Educational Resources Information Center

    Michel, Roberta M.

    2014-01-01

    This article details a faculty learning community (FLC) that started in 2009 on the campus of a Midwestern University and has evolved into an interdisciplinary research, teaching and social community of practice and learning called SurPriSe. SurPriSe is an acronym that reflects the interest area of the FLC; Sur for surveillance, Pri for privacy,…

  20. Etude des effets du martelage repetitif sur les contraintes residuelles

    NASA Astrophysics Data System (ADS)

    Hacini, Lyes

    L'assemblage par soudage peut engendrer des contraintes residuelles. Ces contraintes provoquent des fissurations prematurees et un raccourcissement de la duree de vie des composants. Dans ce contexte, le martelage robotise est utilise pour relaxer ces contraintes residuelles. Trois volets sont presentes: le premier est l'evaluation des effets des impacts unitaires repetes sur le champ de contraintes developpe dans des plaques d'acier inoxydable austenitique 304L vierges ou contenant des contraintes residuelles initiales. Dans la deuxieme partie de ce projet, le martelage est applique grace au robot SCOMPI. Les contraintes residuelles induites et relaxees par martelage sont ensuite mesurees par la methode des contours, qui a ete adaptee a cet effet. Dans la troisieme partie, le martelage est modelise par la methode des elements finis. Un modele axisymetrique developpe grace au logiciel ANSYS permet de simuler des impacts repetes d'un marteau elastique sur une plaque ayant un comportement elastoplastique.

  1. Effets des electrons secondaires sur l'ADN

    NASA Astrophysics Data System (ADS)

    Boudaiffa, Badia

    Les interactions des electrons de basse energie (EBE) representent un element important en sciences des radiations, particulierement, les sequences se produisant immediatement apres l'interaction de la radiation ionisante avec le milieu biologique. Il est bien connu que lorsque ces radiations deposent leur energie dans la cellule, elles produisent un grand nombre d'electrons secondaires (4 x 104/MeV), qui sont crees le long de la trace avec des energies cinetiques initiales bien inferieures a 20 eV. Cependant, il n'y a jamais eu de mesures directes demontrant l'interaction de ces electrons de tres basse energie avec l'ADN, du principalement aux difficultes experimentales imposees par la complexite du milieu biologique. Dans notre laboratoire, les dernieres annees ont ete consacrees a l'etude des phenomenes fondamentaux induits par impact des EBE sur differentes molecules simples (e.g., N2, CO, O2, H2O, NO, C2H 4, C6H6, C2H12) et quelques molecules complexes dans leur phase solide. D'autres travaux effectues recemment sur des bases de l'ADN et des oligonucleotides ont montre que les EBE produisent des bris moleculaires sur les biomolecules. Ces travaux nous ont permis d'elaborer des techniques pour mettre en evidence et comprendre les interactions fondamentales des EBE avec des molecules d'interet biologique, afin d'atteindre notre objectif majeur d'etudier l'effet direct de ces particules sur la molecule d'ADN. Les techniques de sciences des surfaces developpees et utilisees dans les etudes precitees peuvent etre etendues et combinees avec des methodes classiques de biologie pour etudier les dommages de l'ADN induits par l'impact des EBE. Nos experiences ont montre l'efficacite des electrons de 3--20 eV a induire des coupures simple et double brins dans l'ADN. Pour des energies inferieures a 15 eV, ces coupures sont induites par la localisation temporaire d'un electron sur une unite moleculaire de l'ADN, ce qui engendre la formation d'un ion negatif transitoire

  2. Malformations vasculaires au cours du syndrome de Williams-Beuren: à propos de trois nouvelles observations

    PubMed Central

    Sator, Hicham; Rhouni, Fatima Ezzahra; Benjouad, Ibitihale; Rhouni, Fatima Ezzahra; Benjouad, Ibitihale; Dafiri, Rachida; Chat, Latifa

    2016-01-01

    Le syndrome de Williams-Beuren est une maladie génétique rare, il associe classiquement une dysmorphie faciale assez spécifique, des malformations cardiovasculaires et un profil neuropsychologique particulier. Nous rapportons les observations de trois enfants atteints du syndrome de Williams-Beuren en insistant surtout sur les anomalies vasculaires observées sur l'angio-scanner et angio-IRM. PMID:27200143

  3. Le défi de la recherche sur les médicaments et du traitement des enfants au Canada

    PubMed Central

    Rieder, Michael J

    2011-01-01

    RÉSUMÉ Les enfants ont toujours été des « orphelins thérapeutiques ». De nombreux médicaments n’ont pas fait l’objet d’études auprès des enfants et des adolescents ou leur utilisation n’est pas autorisée officiellement auprès d’eux, ce qui crée un défi constant en matière d’élaboration et de définition de pharmacothérapies à la sécurité et l’efficacité optimales au sein du groupe d’âge pédiatrique. Depuis dix ans, des réseaux ont germé aux États-Unis et en Europe afin d’accroître la recherche sur les médicaments dans ce groupe, mais aucune évolution comparable ne s’observe au Canada. Le présent document de principes expose le contexte de la situation canadienne et contient des recommandations qui tiennent compte de deux besoins pressants : plus de recherches sur les médicaments axées sur les enfants et les adolescents canadiens, y compris un financement dédié à de telles recherches, et plus d’effectifs pour mener des études ciblées. Ces initiatives devraient être entreprises en collaboration, sur les scènes nationale et internationale, et inclure des démarches stratégiques et novatrices afin de régler les problèmes et enjeux éthiques uniques que présente la recherche sur les médicaments au sein de cette population.

  4. Lignes directrices simplifiées sur les lipides

    PubMed Central

    Allan, G. Michael; Lindblad, Adrienne J.; Comeau, Ann; Coppola, John; Hudson, Brianne; Mannarino, Marco; McMinis, Cindy; Padwal, Raj; Schelstraete, Christine; Zarnke, Kelly; Garrison, Scott; Cotton, Candra; Korownyk, Christina; McCormack, James; Nickel, Sharon; Kolber, Michael R.

    2015-01-01

    Résumé Objectif Produire un guide de pratique clinique comportant une approche simplifiée à la prévention primaire des maladies cardiovasculaires (MCV), en insistant sur l’estimation du risque de MCV et la prise en charge des profils lipidiques à l’intention des cliniciens de soins primaires et leurs équipes; nous avons recherché la contribution de professionnels des soins primaires qui n’avaient que peu ou pas de conflits d’intérêts et nous nous sommes concentrés sur les données probantes de la plus haute qualité accessibles. Méthodes Neuf professionnels de la santé (4 médecins de famille, 2 internistes, 1 infirmière praticienne, 1 infirmière autorisée et 1 pharmacienne) et 1 membre non votant (pharmacienne gestionnaire de projet) formaient le comité principal appelé le Lipid Pathway Committee (le comité). La sélection des membres s’est fondée sur la profession, le milieu de pratique et son emplacement. Les membres ont divulgué tous leurs conflits d’intérêts potentiels ou réels. Le processus d’élaboration des lignes directrices était itératif et s’appuyait sur des affichages en ligne, une révision détaillée des données probantes, des réunions par téléphone et en ligne. Le comité a cerné 12 questions prioritaires à répondre. Le groupe de révision des données probantes a répondu à ces questions. À la suite d’un examen des réponses, les principales recommandations ont été formulées par consensus du comité. Nous avons produit une ébauche des lignes directrices qui a ensuite été peaufinée, distribuée à un groupe de cliniciens (médecins de famille, autres spécialistes, pharmaciens, infirmières et infirmières praticiennes) et à des patients pour obtenir de la rétroaction, la réviser en conséquence et le comité l’a ensuite finalisée. Recommandations Des recommandations sont présentées concernant le dépistage et les analyses, les évaluations du risque, le suivi, de même que le r

  5. Structure of thermotoga maritima stationary phase survival protein SurE : a novel acid phosphatase.

    SciTech Connect

    Zhang, R.-G; Skarina, T.; Katz, J. E.; Khachatryan, A; Vyas, S.; Arrowsmith, C. H.; Clarke, S.; Edwards, A.; Joachimiak, A.; Savchenko, A.; Biosciences Division; Univ. of Toronto; Univ. of California; Clinical Genomics Centre /Proteomics, Univ. Health Network

    2001-11-01

    Background: The rpoS, nlpD, pcm, and surE genes are among many whose expression is induced during the stationary phase of bacterial growth. rpoS codes for the stationary-phase RNA polymerase {sigma} subunit, and nlpD codes for a lipoprotein. The pcm gene product repairs damaged proteins by converting the atypical isoaspartyl residues back to L-aspartyls. The physiological and biochemical functions of surE are unknown, but its importance in stress is supported by the duplication of the surE gene in E. coli subjected to high-temperature growth. The pcm and surE genes are highly conserved in bacteria, archaea, and plants. Results: The structure of SurE from Thermotoga maritima was determined at 2.0 Angstroms. The SurE monomer is composed of two domains; a conserved N-terminal domain, a Rossman fold, and a C-terminal oligomerization domain, a new fold. Monomers form a dimer that assembles into a tetramer. Biochemical analysis suggests that SurE is an acid phosphatase, with an optimum pH of 5.5-6.2. The active site was identified in the N-terminal domain through analysis of conserved residues. Structure-based site-directed point mutations abolished phosphatase activity. T. maritima SurE intra- and intersubunit salt bridges were identified that may explain the SurE thermostability. Conclusions: The structure of SurE provided information about the protein's fold, oligomeric state, and active site. The protein possessed magnesium-dependent acid phosphatase activity, but the physiologically relevant substrate(s) remains to be identified. The importance of three of the assigned active site residues in catalysis was confirmed by site-directed mutagenesis.

  6. SUR1-Associated Mechanisms Are Not Involved in Ischemic Optic Neuropathy 1 Day Post-Injury

    PubMed Central

    Nicholson, James D.; Guo, Yan; Bernstein, Steven L.

    2016-01-01

    Ischemia-reperfusion injury after central nervous system (CNS) injury presents a major health care challenge with few promising treatments. Recently, it has become possible to reduce edema after CNS injury by antagonizing a sulfonylurea receptor 1 (SUR1) regulated ion channel expressed after injury. SUR1 upregulation after injury is a necessary precondition for the formation of this channel, and has been implicated in white matter injury after clinical spinal cord trauma. Glibenclamide, an SUR1 antagonist, appears to have neuroprotective effect against cerebral stroke in an open-label small clinical trial and great effectiveness in reducing damage after varied experimental CNS injury models. Despite its importance in CNS injuries, SUR1 upregulation appears to play no part in rodent anterior ischemic optic neuropathy (rAION) injury as tested by real-time PCR and immunohistochemical staining of rAION-injured rat optic nerve (ON). Furthermore, the SUR1 antagonist glibenclamide administered immediately after rAION injury provided no protection to proximal ON microvasculature 1 day post-injury but may reduce optic nerve head edema in a manner unrelated to ON SUR1 expression. Our results suggest that there may be fundamental differences between rAION optic nerve ischemia and other CNS white matter injuries where SUR1 appears to play a role. PMID:27560494

  7. SUR1-Associated Mechanisms Are Not Involved in Ischemic Optic Neuropathy 1 Day Post-Injury.

    PubMed

    Nicholson, James D; Guo, Yan; Bernstein, Steven L

    2016-01-01

    Ischemia-reperfusion injury after central nervous system (CNS) injury presents a major health care challenge with few promising treatments. Recently, it has become possible to reduce edema after CNS injury by antagonizing a sulfonylurea receptor 1 (SUR1) regulated ion channel expressed after injury. SUR1 upregulation after injury is a necessary precondition for the formation of this channel, and has been implicated in white matter injury after clinical spinal cord trauma. Glibenclamide, an SUR1 antagonist, appears to have neuroprotective effect against cerebral stroke in an open-label small clinical trial and great effectiveness in reducing damage after varied experimental CNS injury models. Despite its importance in CNS injuries, SUR1 upregulation appears to play no part in rodent anterior ischemic optic neuropathy (rAION) injury as tested by real-time PCR and immunohistochemical staining of rAION-injured rat optic nerve (ON). Furthermore, the SUR1 antagonist glibenclamide administered immediately after rAION injury provided no protection to proximal ON microvasculature 1 day post-injury but may reduce optic nerve head edema in a manner unrelated to ON SUR1 expression. Our results suggest that there may be fundamental differences between rAION optic nerve ischemia and other CNS white matter injuries where SUR1 appears to play a role.

  8. SUR1-Associated Mechanisms Are Not Involved in Ischemic Optic Neuropathy 1 Day Post-Injury.

    PubMed

    Nicholson, James D; Guo, Yan; Bernstein, Steven L

    2016-01-01

    Ischemia-reperfusion injury after central nervous system (CNS) injury presents a major health care challenge with few promising treatments. Recently, it has become possible to reduce edema after CNS injury by antagonizing a sulfonylurea receptor 1 (SUR1) regulated ion channel expressed after injury. SUR1 upregulation after injury is a necessary precondition for the formation of this channel, and has been implicated in white matter injury after clinical spinal cord trauma. Glibenclamide, an SUR1 antagonist, appears to have neuroprotective effect against cerebral stroke in an open-label small clinical trial and great effectiveness in reducing damage after varied experimental CNS injury models. Despite its importance in CNS injuries, SUR1 upregulation appears to play no part in rodent anterior ischemic optic neuropathy (rAION) injury as tested by real-time PCR and immunohistochemical staining of rAION-injured rat optic nerve (ON). Furthermore, the SUR1 antagonist glibenclamide administered immediately after rAION injury provided no protection to proximal ON microvasculature 1 day post-injury but may reduce optic nerve head edema in a manner unrelated to ON SUR1 expression. Our results suggest that there may be fundamental differences between rAION optic nerve ischemia and other CNS white matter injuries where SUR1 appears to play a role. PMID:27560494

  9. [Marine algae of Baja California Sur, Mexico: nutritional value].

    PubMed

    Carrillo Domínguez, Silvia; Casas Valdez, Margarita; Ramos Ramos, Felipe; Pérez-Gil, Fernando; Sánchez Rodríguez, Ignacio

    2002-12-01

    The Baja California Peninsula is one of the richest regions of seaweed resources in México. The objective of this study was to determine the chemical composition of some marine algae species of Baja California Sur, with an economical potential due to their abundance and distribution, and to promote their use as food for human consumption and animal feeding. The algae studied were Green (Ulva spp., Enteromorpha intestinalis, Caulerpa sertularoides, Bryopsis hypnoides), Red (Laurencia johnstonii, Spyridia filamentosa, Hypnea valentiae) and Brown (Sargassum herporizum, S. sinicola, Padina durvillaei, Hydroclathrus clathrathus, Colpomenia sinuosa). The algae were dried and ground before analysis. In general, the results showed that algae had a protein level less than 11%, except L. johnstonii with 18% and low energy content. The ether extract content was lower than 1%. However, the algae were a good source of carbohydrates and inorganic matter.

  10. 46 CFR 7.135 - Point Sur, CA to Cape Blanco, OR.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... shore. (e) A line drawn from the northwestern tip of Tomales Point to latitude 38°15.1′ N. longitude 123... 46 Shipping 1 2014-10-01 2014-10-01 false Point Sur, CA to Cape Blanco, OR. 7.135 Section 7.135... Pacific Coast § 7.135 Point Sur, CA to Cape Blanco, OR. (a) A line drawn from Monterey Harbor Light “6”...

  11. 46 CFR 7.135 - Point Sur, CA to Cape Blanco, OR.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... shore. (e) A line drawn from the northwestern tip of Tomales Point to latitude 38°15.1′ N. longitude 123... 46 Shipping 1 2012-10-01 2012-10-01 false Point Sur, CA to Cape Blanco, OR. 7.135 Section 7.135... Pacific Coast § 7.135 Point Sur, CA to Cape Blanco, OR. (a) A line drawn from Monterey Harbor Light “6”...

  12. 46 CFR 7.135 - Point Sur, CA to Cape Blanco, OR.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... shore. (e) A line drawn from the northwestern tip of Tomales Point to latitude 38°15.1′ N. longitude 123... 46 Shipping 1 2011-10-01 2011-10-01 false Point Sur, CA to Cape Blanco, OR. 7.135 Section 7.135... Pacific Coast § 7.135 Point Sur, CA to Cape Blanco, OR. (a) A line drawn from Monterey Harbor Light “6”...

  13. 46 CFR 7.135 - Point Sur, CA to Cape Blanco, OR.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... shore. (e) A line drawn from the northwestern tip of Tomales Point to latitude 38°15.1′ N. longitude 123... 46 Shipping 1 2013-10-01 2013-10-01 false Point Sur, CA to Cape Blanco, OR. 7.135 Section 7.135... Pacific Coast § 7.135 Point Sur, CA to Cape Blanco, OR. (a) A line drawn from Monterey Harbor Light “6”...

  14. 46 CFR 7.130 - Point Conception, CA to Point Sur, CA.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false Point Conception, CA to Point Sur, CA. 7.130 Section 7.130 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY PROCEDURES APPLICABLE TO THE PUBLIC BOUNDARY LINES Pacific Coast § 7.130 Point Conception, CA to Point Sur, CA. (a) A line drawn from the southernmost extremity of Fossil Point at longitude...

  15. 46 CFR 7.135 - Point Sur, CA to Cape Blanco, OR.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false Point Sur, CA to Cape Blanco, OR. 7.135 Section 7.135 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY PROCEDURES APPLICABLE TO THE PUBLIC BOUNDARY LINES Pacific Coast § 7.135 Point Sur, CA to Cape Blanco, OR. (a) A line drawn from Monterey Harbor Light “6” to latitude 36°36.5′ N. longitude...

  16. Modelisations des effets de surface sur les jets horizontaux subsoniques d'hydrogene et de methane

    NASA Astrophysics Data System (ADS)

    Gomez, Luis Fernando

    Le developpement des codes et de normes bases sur une methodologie scientifique requiert la capacite de predire l'etendue inflammable de deversements gazeux d'hydrogene sous differentes conditions. Des etudes anterieures ont deja etabli des modeles bases sur les lois de conservation de la mecanique des fluides basees sur des correlations experimentales qui permettent de predire la decroissance de la concentration et de la vitesse d'un gaz le long de l'axe d'un jet libre vertical. Cette etude s'interesse aux effets de proximite a une surface horizontale parallele sur un jet turbulent. Nous nous interessons a son impact sur l'etendue du champ de la concentration et sur l'enveloppe inflammable en particulier. Cette etude est comparative : l'hydrogene est compare au methane. Ceci permet de degager l'influence des effets de difference de la densite sur le comportement du jet, et de comparer le comportement de l'hydrogene aux correlations experimentales, qui ont ete essentiellement etablies pour le methane. Un modele decrivant l'evolution spatio-temporelle du champ de concentration du gaz dilue est propose, base sur la mecanique des fluides computationnelle. Cette approche permet de varier systematiquement les conditions aux frontieres (proximite du jet a la surface, par exemple) et de connaitre en detail les proprietes de l'ecoulement. Le modele est implemente dans le code de simulations par volumes finis de FLUENT. Les resultats des simulations sont compares avec les lois de similitudes decoulant de la theorie des jets d'ecoulements turbulents libres ainsi qu'avec les resultats experimentaux disponibles. L'effet de la difference des masses molaires des constituantes du jet et des constituantes du milieu de dispersion est egalement etudie dans le contexte du comportement d'echelle de la region developpee du jet.

  17. Ability of a rapid HIV testing site to attract and test vulnerable populations: a cross-sectional study on Actuel sur Rue.

    PubMed

    Engler, Kim; Rollet, Kathleen; Lessard, David; Thomas, Réjean; Lebouché, Bertrand

    2016-10-01

    Quebec's HIV epidemic persists, particularly among men who have sex with men (MSM) and in Montreal. Increasing access to HIV testing is necessary and community-based rapid testing offers one strategy. This paper examines the clienteles and activities of a rapid HIV testing site in Montreal, the pilot project Actuel sur Rue. Comparative analyses were conducted with 1357 MSM, 147 heterosexual men and 64 women who visited Actuel sur Rue between July 2012 and November 2013 on socio-demographics, health, drug use, sexual practices/infection and HIV testing/prevention. Significant group differences were observed in each category. Actuel sur Rue received 1901 clients, conducted 1417 rapid HIV tests and tested 77 never-tested individuals. Rapid testing produced a high reactive rate (2%). Only 1/28 of those with reactive tests had no previous HIV testing, and 36% had used post-exposure prophylaxis, suggesting missed opportunities for prevention. Findings highlight diverse client vulnerability profiles and the relevance of checkpoints and further prevention efforts.

  18. Effets de la formation sur la violence conjugale

    PubMed Central

    Zaher, Eman; Keogh, Kelly; Ratnapalan, Savithiri

    2014-01-01

    Résumé Objectif Décrire et évaluer l’efficacité de la formation concernant la violence conjugale pour améliorer les connaissances et permettre la reconnaissance et la prise en charge par les médecins des femmes victimes de violence. Sources des données On a fait une recension dans la base de données des révisions systématiques de Cochrane, MEDLINE, PubMed, PsycINFO, ERIC et EMBASE pour trouver des articles publiés entre le 1e janvier 2000 et le 1e novembre 2012. Des recherches manuelles ont complété cette recension pour cerner des articles pertinents à l’aide d’une stratégie de recherche combinant des textes, mots et expressions MeSH. Sélection des études On a choisi des études randomisées contrôlées qui portaient sur des interventions éducatives à l’intention des médecins et fournissaient des données sur les effets des interventions. Synthèse On a inclus 9 études randomisées contrôlées qui décrivaient différentes approches pédagogiques et diverses mesures des résultats. Trois études examinaient les effets d’interventions éducatives pour des médecins en formation postdoctorale et ont constaté une augmentation des connaissances, mais il n’y a eu aucun changement dans le comportement en ce qui a trait à l’identification des victimes de violence conjugale. Six études portaient sur des interventions éducatives pour des médecins en pratique active. Trois d’entre elles utilisaient une approche à multiples facettes pour les médecins, qui combinait une formation ainsi que des interventions de soutien de la part du système pour changer les comportements des médecins, comme une sensibilisation générale accrue à la violence conjugale au moyen de brochures et d’affiches, des aide-mémoire pour rappeler aux médecins comment identifier les victimes, des moyens pour faciliter l’accès des médecins à des services de soutien pour les victimes, la réalisation d’audits et la fourniture de rétroaction. Les

  19. Sur Lago area, Venezuela: Three dimensional integrated seismic interpretation

    SciTech Connect

    Growcott, A.; McIan, A.; Ramirez, R. )

    1993-02-01

    In 1988, 550 square km of 3D seismic data were acquired in the Sur Del Lago area. The aims of the survey were (1) To better define structures already identified from the existing 1 [times] 1 km 2D seismic grid at the level of potential Cretaceous limestone reservoirs and (2) To further study the prospectivity of potential structural and stratigraphic traps within the Tertiary section. Detailed interpretation of the 3D survey using an interactive workstation led to an improved structural definition at the Cogollo limestone level and the identification of fault related inversion lineaments and basement related Cretaceous limestone structures. Based upon the new seismic interpretation a 4 well exploration project was planned. The new program commenced with the drilling of exploration well SLA-7-IX in 1991 which proved commercial amounts of hydrocarbons in the western part of the area. Detailed information collected from the exploration wells includes a comprehensive electric log suite, ditch cuttings and vertical seismic profiles. The information is being used as detailed lithological, stratigraphic and seismic data input for velocity modeling, ray trace modeling, seismic attribute analysis, and reservoir characterization software in order to further understand the structural and stratigraphic potential of the area.

  20. SurR regulates hydrogen production in Pyrococcus furiosus by a sulfur-dependent redox switch

    PubMed Central

    Yang, Hua; Lipscomb, Gina L.; Keese, Annette M.; Schut, Gerrit J.; Thomm, Michael; Adams, Michael W. W.; Wang, Bi Cheng; Scott, Robert A.

    2010-01-01

    SUMMARY We present structural and biochemical evidence for a redox switch in the archaeal transcriptional regulator SurR of Pyrococcus furiosus, a hyperthermophilic anaerobe. P. furiosus produces H2 during fermentation, but undergoes a metabolic shift to produce H2S when elemental sulfur (S0) becomes available. Changes in gene expression occur within minutes of S0 addition, and the majority of these S0-responsive genes are regulatory targets of SurR, a key regulator involved in primary S0 response. SurR was shown in vitro to have dual functionality, activating transcription of some of these genes, notably the hydrogenase operons, and repressing others, including a gene encoding sulfur reductase. This work demonstrates via biochemical and structural evidence that the activity of SurR is modulated by cysteine residues in a CxxC motif that constitute a redox switch. Oxidation of the switch with S0 inhibits sequence-specific DNA binding by SurR, leading to deactivation of genes related to H2 production and derepression of genes involved in S0 metabolism. PMID:20598080

  1. The Activity of Escherichia coli Chaperone SurA Is Regulated by Conformational Changes Involving a Parvulin Domain

    PubMed Central

    Soltes, Garner R.; Schwalm, Jaclyn; Ricci, Dante P.

    2016-01-01

    ABSTRACT The periplasmic chaperone SurA is critical for the biogenesis of outer membrane proteins (OMPs) and, thus, the maintenance of membrane integrity in Escherichia coli. The activity of this modular chaperone has been attributed to a core chaperone module, with only minor importance assigned to the two SurA peptidyl-prolyl isomerase (PPIase) domains. In this work, we used synthetic phenotypes and covalent tethering to demonstrate that the activity of SurA is regulated by its PPIase domains and, furthermore, that its activity is correlated with the conformational state of the chaperone. When combined with mutations in the β-barrel assembly machine (BAM), SurA mutations resulting in deletion of the second parvulin domain (P2) inhibit OMP assembly, suggesting that P2 is involved in the regulation of SurA. The first parvulin domain (P1) potentiates this autoinhibition, as mutations that covalently tether the P1 domain to the core chaperone module severely impair OMP assembly. Furthermore, these inhibitory mutations negate the suppression of and biochemically stabilize the protein specified by a well-characterized gain-of-function mutation in P1, demonstrating that SurA cycles between distinct conformational and functional states during the OMP assembly process. IMPORTANCE This work reveals the reversible autoinhibition of the SurA chaperone imposed by a heretofore underappreciated parvulin domain. Many β-barrel-associated outer membrane (OM) virulence factors, including the P-pilus and type I fimbriae, rely on SurA for proper assembly; thus, a mechanistic understanding of SurA function and inhibition may facilitate antibiotic intervention against Gram-negative pathogens, such as uropathogenic Escherichia coli, E. coli O157:H7, Shigella, and Salmonella. In addition, SurA is important for the assembly of critical OM biogenesis factors, such as the lipopolysaccharide (LPS) transport machine, suggesting that specific targeting of SurA may provide a useful means to

  2. Profil bactériologique du pied diabétique et son impact sur le choix des antibiotiques

    PubMed Central

    Zemmouri, Adil; Tarchouli, Mohamed; Benbouha, Abdellatif; Lamkinsi, Tarik; Bensghir, Mustapha; Elouennass, Mostafa; Haimeur, Cherqui

    2015-01-01

    Introduction Analyse du profil bactériologique des pieds diabétiques pris en charge à l'hôpital militaire de Rabat et son influence sur l'antibiothérapie de première intention. Méthodes Etude prospective non randomisée étalée sur 18 mois, ayant concerné 105 patients. Après recueil des données et en attente des résultats bactériologiques nos patients ont été divisés en deux groupes: un groupe a été mis sous Amoxicilline + Acide clavulanique + Gentamycine (59 patients) et un groupe sous Ertapénème±Gentamycine (46 patients). Résultats L’étude a regroupé 85 hommes et 20 femmes (sexe ratio = 4.26). L’âge moyen est de 64.4 ans. La gangrène a été observée chez 79% des malades; elle était humide-donc surinfectée en principe- dans 43% des cas. Par ailleurs, 67% des malades ont un chiffre de globules blancs 12000 définissant une infection sévère. L'ostéolyse a été mise en évidence chez 27% de nos patients. Parmi les différentes techniques de prélèvements: 81% ont été profonds dont 21% de biopsie osseuse per opératoire et 14% de prélèvements combinés. 42% de ces prélèvements sont poly microbiens et 21% sont stériles. Les résultats bactériologiques viennent confirmer la prédominance des bactéries aérobies à Gram positif. Le taux de remplacement de l'Ertapénème est de 22% contre un taux de 50% pour l'Amoxiclav. Conclusion L'antibiothérapie ne doit être instaurée qu'en cas d'infection du pied diabétique diagnostiquée sur les critères cliniques établis par les consensus internationaux récents. Le respect des mesures de lutte contre la diffusion de la résistance bactérienne s'avère primordiale. PMID:27386024

  3. Structure and function of an archaeal homolog of survival protein E (SurEalpha): an acid phosphatase with purine nucleotide specificity.

    PubMed

    Mura, Cameron; Katz, Jonathan E; Clarke, Steven G; Eisenberg, David

    2003-03-01

    The survival protein E (SurE) family was discovered by its correlation to stationary phase survival of Escherichia coli and various repair proteins involved in sustaining this and other stress-response phenotypes. In order to better understand this ancient and well-conserved protein family, we have determined the 2.0A resolution crystal structure of SurEalpha from the hyperthermophilic crenarchaeon Pyrobaculum aerophilum (Pae). This first structure of an archaeal SurE reveals significant similarities to and differences from the only other known SurE structure, that from the eubacterium Thermatoga maritima (Tma). Both SurE monomers adopt similar folds; however, unlike the Tma SurE dimer, crystalline Pae SurEalpha is predominantly non-domain swapped. Comparative structural analyses of Tma and Pae SurE suggest conformationally variant regions, such as a hinge loop that may be involved in domain swapping. The putative SurE active site is highly conserved, and implies a model for SurE bound to a potential substrate, guanosine-5'-monophosphate (GMP). Pae SurEalpha has optimal acid phosphatase activity at temperatures above 90 degrees C, and is less specific than Tma SurE in terms of metal ion requirements. Substrate specificity also differs between Pae and Tma SurE, with a more specific recognition of purine nucleotides by the archaeal enzyme. Analyses of the sequences, phylogenetic distribution, and genomic organization of the SurE family reveal examples of genomes encoding multiple surE genes, and suggest that SurE homologs constitute a broad family of enzymes with phosphatase-like activities.

  4. The Classroom as Big Sur: Notes on the Liaison Between Evaluation and Professional Growth

    ERIC Educational Resources Information Center

    Sneeden, Ralph

    2013-01-01

    Bill Frisell's new album ("Big Sur") was heralded with a short documentary about its impulse and inception: Frisell's retreat to an isolated coastal ranch in Central California. In the video, he describes the influence of the place, the dramatic and evocative landscape, and how it ultimately became the subject and theme for the…

  5. Seafloor Rocks and Sediments of the Continental Shelf From Monterey Bay to Point Sur, California

    USGS Publications Warehouse

    Eittreim, Stephen L.; Anima, Roberto J.; Stevenson, Andrew J.; Wong, Florence L.

    2000-01-01

    Introduction Acoustic swath mapping of the greater Monterey Bay area continental shelf from Point Ano Nuevo to Point Sur reveals complex patterns of rock outcrops on the shelf, and coarse sand bodies that occur in distinct depressions on the inner and mid-shelves. This publication portrays the seafloor components in a 36- by 48-inch map sheet at 1:100,000 scale.

  6. Reflections on "Petit Battement sur le Cou de Pied": Is It Still Relevant?

    ERIC Educational Resources Information Center

    Paskevska, Anna

    2007-01-01

    This article presents multiple perspectives of "petit battement sur le cou de pied". These perspectives include historical, biomechanical, and pedagogic points of view. The article offers useful information for ballet specialists and applied research studies aimed at ballet pedagogy. (Contains 2 tables and 5 figures.)

  7. Differential mechanisms of Cantú syndrome-associated gain of function mutations in the ABCC9 (SUR2) subunit of the KATP channel.

    PubMed

    Cooper, Paige E; Sala-Rabanal, Monica; Lee, Sun Joo; Nichols, Colin G

    2015-12-01

    Cantú syndrome (CS) is a rare disease characterized by congenital hypertrichosis, distinct facial features, osteochondrodysplasia, and cardiac defects. Recent genetic analysis has revealed that the majority of CS patients carry a missense mutation in ABCC9, which codes for the sulfonylurea receptor SUR2. SUR2 subunits couple with Kir6.x, inwardly rectifying potassium pore-forming subunits, to form adenosine triphosphate (ATP)-sensitive potassium (K(ATP)) channels, which link cell metabolism to membrane excitability in a variety of tissues including vascular smooth muscle, skeletal muscle, and the heart. The functional consequences of multiple uncharacterized CS mutations remain unclear. Here, we have focused on determining the functional consequences of three documented human CS-associated ABCC9 mutations: human P432L, A478V, and C1043Y. The mutations were engineered in the equivalent position in rat SUR2A (P429L, A475V, and C1039Y), and each was coexpressed with mouse Kir6.2. Using macroscopic rubidium ((86)Rb(+)) efflux assays, we show that K(ATP) channels formed with P429L, A475V, or C1039Y mutants enhance K(ATP) activity compared with wild-type (WT) channels. We used inside-out patch-clamp electrophysiology to measure channel sensitivity to ATP inhibition and to MgADP activation. For P429L and A475V mutants, sensitivity to ATP inhibition was comparable to WT channels, but activation by MgADP was significantly greater. C1039Y-dependent channels were significantly less sensitive to inhibition by ATP or by glibenclamide, but MgADP activation was comparable to WT. The results indicate that these three CS mutations all lead to overactive K(ATP) channels, but at least two mechanisms underlie the observed gain of function: decreased ATP inhibition and enhanced MgADP activation. PMID:26621776

  8. Differential mechanisms of Cantú syndrome–associated gain of function mutations in the ABCC9 (SUR2) subunit of the KATP channel

    PubMed Central

    Cooper, Paige E.; Sala-Rabanal, Monica; Lee, Sun Joo

    2015-01-01

    Cantú syndrome (CS) is a rare disease characterized by congenital hypertrichosis, distinct facial features, osteochondrodysplasia, and cardiac defects. Recent genetic analysis has revealed that the majority of CS patients carry a missense mutation in ABCC9, which codes for the sulfonylurea receptor SUR2. SUR2 subunits couple with Kir6.x, inwardly rectifying potassium pore-forming subunits, to form adenosine triphosphate (ATP)-sensitive potassium (KATP) channels, which link cell metabolism to membrane excitability in a variety of tissues including vascular smooth muscle, skeletal muscle, and the heart. The functional consequences of multiple uncharacterized CS mutations remain unclear. Here, we have focused on determining the functional consequences of three documented human CS-associated ABCC9 mutations: human P432L, A478V, and C1043Y. The mutations were engineered in the equivalent position in rat SUR2A (P429L, A475V, and C1039Y), and each was coexpressed with mouse Kir6.2. Using macroscopic rubidium (86Rb+) efflux assays, we show that KATP channels formed with P429L, A475V, or C1039Y mutants enhance KATP activity compared with wild-type (WT) channels. We used inside-out patch-clamp electrophysiology to measure channel sensitivity to ATP inhibition and to MgADP activation. For P429L and A475V mutants, sensitivity to ATP inhibition was comparable to WT channels, but activation by MgADP was significantly greater. C1039Y-dependent channels were significantly less sensitive to inhibition by ATP or by glibenclamide, but MgADP activation was comparable to WT. The results indicate that these three CS mutations all lead to overactive KATP channels, but at least two mechanisms underlie the observed gain of function: decreased ATP inhibition and enhanced MgADP activation. PMID:26621776

  9. Eisosomes promote the ability of Sur7 to regulate plasma membrane organization in Candida albicans

    PubMed Central

    Wang, Hong X.; Douglas, Lois M.; Veselá, Petra; Rachel, Reinhard; Malinsky, Jan; Konopka, James B.

    2016-01-01

    The plasma membrane of the fungal pathogen Candida albicans forms a protective barrier that also mediates many processes needed for virulence, including cell wall synthesis, invasive hyphal morphogenesis, and nutrient uptake. Because compartmentalization of the plasma membrane is believed to coordinate these diverse activities, we examined plasma membrane microdomains termed eisosomes or membrane compartment of Can1 (MCC), which correspond to ∼200-nm-long furrows in the plasma membrane. A pil1∆ lsp1∆ mutant failed to form eisosomes and displayed strong defects in plasma membrane organization and morphogenesis, including extensive cell wall invaginations. Mutation of eisosome proteins Slm2, Pkh2, and Pkh3 did not cause similar cell wall defects, although pkh2∆ cells formed chains of furrows and pkh3∆ cells formed wider furrows, identifying novel roles for the Pkh protein kinases in regulating furrows. In contrast, the sur7∆ mutant formed cell wall invaginations similar to those for the pil1∆ lsp1∆ mutant even though it could form eisosomes and furrows. A PH-domain probe revealed that the regulatory lipid phosphatidylinositol 4,5-bisphosphate was enriched at sites of cell wall invaginations in both the sur7∆ and pil1∆ lsp1∆ cells, indicating that this contributes to the defects. The sur7∆ and pil1∆ lsp1∆ mutants displayed differential susceptibility to various types of stress, indicating that they affect overlapping but distinct functions. In support of this, many mutant phenotypes of the pil1∆ lsp1∆ cells were rescued by overexpressing SUR7. These results demonstrate that C. albicans eisosomes promote the ability of Sur7 to regulate plasma membrane organization. PMID:27009204

  10. Effets de L'anisotropie Cristalline et du Desordre Controle Sur les Proprietes Optiques et Phononiques des Composes Semiconducteurs ZIRCONIUM(1-X) Hafnium(x) SOUFRE(3)

    NASA Astrophysics Data System (ADS)

    Ait-Ouali, Abderrahmane

    Dans ce travail, nous presentons l'etude de l'effet de l'anisotropie cristalline et du desordre substitutionnel controle sur les proprietes electroniques et vibrationnelles des composes semiconducteurs Zr_{rm 1-x}Hf_{x} S_3. Les proprietes phononiques sont ete etudiees en spectroscopie Raman. Les mesures systematiques des spectres polarises de tous les composes nous ont permis d'identifier tous les phonons predits par la theorie des groupes et de suivre l'evolution de leur frequence avec la concentration de hafnium. L'analyse plus approfondie par un procede de lissage des spectres nous a permis detudier l'effet du desordre controle sur la largeur des modes phononiques. Les resultats de cette analyse ont ete confrontes aux predictions d'un modele developpe pour une chai ne diatomique desordonnee et ameliore suite a nos observations experimentales. La forme en cloche predite par ce dernier pour la variation de la largeur du mode optique de la chai ne est observee pour trois phonons de symetrie Bg. L'accord est excellent pour X > 0.5 pour deux des trois modes et ce, sans aucun parametre ajustable. Cette etude nous a permis, d'une part, de conclure que les modes Bg se comportent comme s'ils etaient sur une chai ne isolee et que, par consequent, les deux chai nes composant la cellule unite de nos cristaux sont tres faiblement liees et, d'autre part, de confirmer la symetrie des modes telle que deduite des spectres polarises. Les proprietes electroniques du ZrS_3 ont ete etudiees par des mesures polarisees du coefficient d'absorption pres de son gap indirect. L'evolution des spectres avec la temperature nous a permis d'identifier deux gaps paralleles differents et un gap perpendiculaire confirmant ainsi le modele de la structure de bande base sur les etats electroniques moleculaires de l'ion (S _2)^2. L'analyse detaillee des differentes structures du coefficient d'absorption indique clairement un caractere bidimensionnel du gap indirect. L'effet du desordre

  11. L’opinion des étudiants en médecine de Québec sur les punitions corporelles

    PubMed Central

    Labbé, Jean; Laflamme, Nathalie; Makosso-Kallyth, Sun

    2012-01-01

    OBJECTIF : L’objectif de la présente étude est de décrire l’opinion des étudiants en médecine de l’Université Laval sur le sujet controversé des punitions corporelles envers les enfants. MÉTHODOLOGIE : Un sondage a été réalisé auprès des étudiants en quatrième année de médecine de l’Université Laval pendant cinq années consécutives, soit de l’année scolaire 2006–2007 jusqu’à celle de 2010–2011 inclusivement, à l’occasion d’un séminaire portant sur la maltraitance envers les enfants. RÉSULTATS : Sur les 712 étudiants interrogés, 74 % étaient de sexe féminin et 91 % étaient âgés de moins de 30 ans. Concernant les punitions corporelles envers les enfants, 22 % des répondants s’y sont déclarés favorables. Plus de garçons que de filles se sont prononcés en faveur de cette pratique disciplinaire, soit 31 % des garçons par rapport à 18 % des filles respectivement (RC rajusté = 2,2, IC 95 % :1,4 à 3,4; p=0,0003). Près de 36 % des étudiants ayant eu des punitions corporelles y étaient favorables, comparativement à seulement 4 % de ceux qui n’avaient pas connu cette forme de discipline (RC rajusté = 16,5, IC 95 % :8,6 à 31,4; p<0,0001). Parmi ceux qui ont mentionné avoir été victimes d’abus physique, 25 % se sont déclarés en faveur de cette pratique, ce qui est similaire au 21 % observés chez ceux qui n’en ont pas été victimes (p=0,52). CONCLUSION : Alors que plusieurs organismes médicaux se sont prononcés contre l’utilisation des punitions corporelles, plus d’un futur médecin sur cinq à Québec se déclare favorable à cette méthode disciplinaire et pourrait influencer la conduite des parents en ce sens. PMID:24179417

  12. Syndrome de Sweet: étude clinique et natomopathologique sur 5 ans

    PubMed Central

    Bouzidi, Hanae; Gallouj, Salim; Amraoui, Nissrine; Mernissi, Fatima Zahra; Harmouch, Taoufiq

    2015-01-01

    Le syndrome de Sweet ou dermatose aiguë fébrile neutrophilique est une maladie inflammatoire rare à expression cutanée prédominante, appartenant au groupe des dermatoses neutrophiliques. Il est caractérisé par le polymorphisme de son expression clinique et la diversité des maladies qui peuvent lui être associées. Le but de ce travail était d’étudier les particularités cliniques, anatomopathologiques, thérapeutiques et évolutives du syndrome de Sweet. Nous rapportons une étude rétrospective et descriptive de 25 cas de syndrome de Sweet observés dans les services de dermatologie et d'anatomie pathologique du centre hospitalier universitaire de Fès sur une période de 5 ans. Notre série était constituée de 5 hommes et de 20 femmes avec un sex-ratio (hommes/femmes) de 0,25. L’âge moyen des patients était de 47 ans avec des extrêmes allant de 11 à 75 ans. Des maladies associées étaient retrouvées chez 17 patients: hémopathies (deux cas), tumeur solide (1cas), maladie chronique de l'intestin (1cas), tuberculose (1 cas), diabète (trois cas) et infections (9 cas). Deux patientes étaient enceintes au moment du diagnostic. Les manifestations cutanées étaient polymorphes avec atteintes muqueuses dans deux cas. Les lésions siégeaient le plus souvent au niveau acral. Histologiquement, le derme était le siège d'un infiltrat dense et diffus riche en polynucléaires neutrophiles dans tous les cas. Une inflammation de la paroi des vaisseaux étaient observées dans trois cas. Le syndrome de Sweet peut être révélateur ou précéder des maladies associées, ce qui impose une surveillance rigoureuse et prolongée. PMID:26185554

  13. Influence des effets de température quasi-statiques du premier ordre sur les dispositifs à ondes de surface transverses sur sillons gravés

    NASA Astrophysics Data System (ADS)

    Ballandras, S.; Gavignet, E.; Bigler, E.

    1995-02-01

    The present study is devoted to the theoretical calculation of the first order quasi-static temperature coefficient of surface transverse waves which can propagate under shallow groove gratings. The model presented here associates an analytical description of non-perturbed surface transverse waves on an anisotropic substrate developed by Auld and Tiersten's perturbation method. This approach has been implemented in the case of quartz delay lines corrugated with rectangular grooves. It is shown that singly rotated quartz cuts can be theoretically found exhibiting a first-order temperature coefficient close to zero. The sensitivity of this coefficient versus the groove depth is also theoretically demonstrated. La présente étude consiste à calculer le coefficient de température du premier ordre d'un résonateur à ondes transverses de surface se propageant sous un réseau de sillons gravés de forme quelconque. Ce calcul fait intervenir un modèle analytique de propagation des ondes sur un substrat anisotrope développé par Auld et une méthode de perturbation mise au point par Tiersten. Cette approche théorique a été mise en oeuvre pour traiter le cas des dispositifs à sillons gravés de profil rectangulaire sur quartz. On montre ainsi qu'il existe des coupes de quartz à simple rotation présentant un coefficient de température du premier ordre théorique proche de zéro. L'influence de la profondeur de gravure des sillons sur ce coefficient est également mise en évidence théoriquement.

  14. Évolution des lignes directrices sur le traitement de la dyslipidémie

    PubMed Central

    John Bosomworth, N.

    2014-01-01

    Résumé Objectif Comprendre comment les nouvelles lignes directrices sur la prise en charge du risque cardiovasculaire publiées par l’American Heart Association et l’American College of Cardiology (AHA-ACC) peuvent être interprétées et utilisées dans le contexte canadien. Sources des données Les lignes directrices de l’AHA-ACC ont été examinées, de même que toutes les références. Des recherches indépendantes dans PubMed ont été effectuées pour inclure l’ajout aux statines d’autres antihyperlipidémiants et l’emploi de calculatrices médicales visant à aider le patient à comprendre. Message principal Les nouvelles lignes directrices de l’AHA-ACC s’appuient sur les meilleures données probantes disponibles actuellement en matière de traitement de la dyslipidémie. Cela inclut le risque cardiovasculaire (CV) sur 10 ans comme seuil thérapeutique au lieu du taux de cholestérol des lipoprotéines de faible densité, de même que l’abandon des cibles thérapeutiques de lipoprotéines de faible densité. On met de plus en plus l’accent sur les interventions alimentaires et l’exercice, avec l’amorce d’un effort pour quantifier l’effet de ces interventions. Les statines constituent la principale intervention pharmacologique, et l’ajout d’autres médicaments pour accentuer la baisse lipidique n’est plus recommandé. En ce qui concerne l’application au Canada, les tables de risque de Framingham sont plus appropriées pour évaluer le risque que les équations de cohortes regroupées utilisées aux États-Unis. Les calculatrices du risque de maladie cardiovasculaire (MCV) devraient contenir de l’information sur l’âge cardiovasculaire et devraient pouvoir illustrer le risque et les interventions de rechange afin d’aider le patient à comprendre et de favoriser la prise de décision éclairée. Conclusion L’attention sur les meilleures données probantes concernant le risque CV peut simplifier le traitement de la

  15. Effet de l'interaction coulombienne sur la localisation d'Anderson dans le gaz bidimensionnel d'électrons

    NASA Astrophysics Data System (ADS)

    Fleury, G.

    2010-09-01

    Nous étudions l’effet des interactions coulombiennes sur la localisation d’Anderson dans le gaz bidimensionnel d’électrons désordonné. L’objectif est de statuer sur la question de l’existence de métaux à deux dimensions. En l’absence d’interaction, la théorie d’échelle de la localisation prédit qu’un désordre infinitésimal suffit à localiser la fonction d’onde électronique et donc à rendre le système isolant à température nulle (Abrahams et al., 1979). Dans certaines limites extrêmes, les interactions peuvent être prises en compte et l’on aboutit également à un état isolant. Cependant, aucune théorie analytique ne permet de traiter le régime quantique non-perturbatif où désordre et interaction sont intermédiaires. Expérimentalement, il est possible de l’explorer dans des échantillons de haute mobilité et basse densité. Depuis 1994, des comportements métalliques inexpliqués y ont été observés (Kravchenko et al., 1994). Nous avons mis au point une méthode numérique permettant d’étudier le problème couplé de la localisation d’Anderson en présence d’interaction. Cette méthode mêle Monte Carlo quantique à température nulle et théorie d’échelle pour la conductance de Thouless. Nous trouvons que la théorie d’échelle de la localisation est préservée en présence d’interaction et donc que le gaz bidimensionnel, même corrélé, est isolant à température nulle. Nos résultats montrent de plus que les interactions délocalisent le gaz bidimensionnel et que cet effet de délocalisation est accru en présence de dégénérescence de vallées. Ils nous permettent de proposer un mécanisme simple rendant compte des principales caractéristiques des comportements métalliques observés expérimentalement.

  16. Réalisation de réseaux sur polymères par laser UV

    NASA Astrophysics Data System (ADS)

    Castex, M. C.; Fischer, A.; Simeonov, D.; Adès, D.; Siove, A.

    2003-06-01

    Nous présentons ici une méthode très simple de réalisation de réseaux d'amplitude de pas sub-micronique sur des films polymères à base de carbazote déposés sur des substrat de silice. Les réseaux sont fabriqués en irradiant avec un faisceau laser à 193nm un masque de phase placé au contact du film. La qualité des réseaux obtenus permet désormais d'envisager la réalisation de micro-cavités lasers de type planaire permettant de sélectionner une émission laser monomode autour de 400nm.

  17. A new species of Rhadinella (Serpentes: Colubridae) from the Sierra Madre del Sur of Guerrero, Mexico.

    PubMed

    Campillo, Gustavo; Dávila-Galavíz, Luis Fernando; Flores-Villela, Oscar; Campbell, Jonathan A

    2016-04-12

    We describe a new species of Rhadinella from the Sierra Madre del Sur of Guerrero, Mexico, a region where the genus was previously unknown. This diminutive species is a member of a group of snakes previously allocated in the Rhadinaea godmani group, and more recently transferred to the genus Rhadinella. These snakes may have conspicuous dark longitudinal striping on a pale brown to orange background or may have dark brown to blackish dorsal ground coloration, which mostly or completely obfuscates a pattern of longitudinal striping. The new species is mostly dark with barely discernible slightly paler or darker striping (depending on how striping is interpreted). The closest relative of the new species, on the basis of morphological similarities and biogeography, appears to be Rhadinella donaji which occurs to the east in the Sierra Madre del Sur of Oaxaca about 275 km from the type-locality of the new species.

  18. ABCC9/SUR2 in the brain: Implications for hippocampal sclerosis of aging and a potential therapeutic target.

    PubMed

    Nelson, Peter T; Jicha, Gregory A; Wang, Wang-Xia; Ighodaro, Eseosa; Artiushin, Sergey; Nichols, Colin G; Fardo, David W

    2015-11-01

    The ABCC9 gene and its polypeptide product, SUR2, are increasingly implicated in human neurologic disease, including prevalent diseases of the aged brain. SUR2 proteins are a component of the ATP-sensitive potassium ("KATP") channel, a metabolic sensor for stress and/or hypoxia that has been shown to change in aging. The KATP channel also helps regulate the neurovascular unit. Most brain cell types express SUR2, including neurons, astrocytes, oligodendrocytes, microglia, vascular smooth muscle, pericytes, and endothelial cells. Thus it is not surprising that ABCC9 gene variants are associated with risk for human brain diseases. For example, Cantu syndrome is a result of ABCC9 mutations; we discuss neurologic manifestations of this genetic syndrome. More common brain disorders linked to ABCC9 gene variants include hippocampal sclerosis of aging (HS-Aging), sleep disorders, and depression. HS-Aging is a prevalent neurological disease with pathologic features of both neurodegenerative (aberrant TDP-43) and cerebrovascular (arteriolosclerosis) disease. As to potential therapeutic intervention, the human pharmacopeia features both SUR2 agonists and antagonists, so ABCC9/SUR2 may provide a "druggable target", relevant perhaps to both HS-Aging and Alzheimer's disease. We conclude that more work is required to better understand the roles of ABCC9/SUR2 in the human brain during health and disease conditions.

  19. Multimodal 3-D reconstruction of human anatomical structures using SurLens Visualization System.

    PubMed

    Adeshina, A M; Hashim, R; Khalid, N E A; Abidin, S Z Z

    2013-03-01

    In the medical diagnosis and treatment planning, radiologists and surgeons rely heavily on the slices produced by medical imaging devices. Unfortunately, these image scanners could only present the 3-D human anatomical structure in 2-D. Traditionally, this requires medical professional concerned to study and analyze the 2-D images based on their expert experience. This is tedious, time consuming and prone to error; expecially when certain features are occluding the desired region of interest. Reconstruction procedures was earlier proposed to handle such situation. However, 3-D reconstruction system requires high performance computation and longer processing time. Integrating efficient reconstruction system into clinical procedures involves high resulting cost. Previously, brain's blood vessels reconstruction with MRA was achieved using SurLens Visualization System. However, adapting such system to other image modalities, applicable to the entire human anatomical structures, would be a meaningful contribution towards achieving a resourceful system for medical diagnosis and disease therapy. This paper attempts to adapt SurLens to possible visualisation of abnormalities in human anatomical structures using CT and MR images. The study was evaluated with brain MR images from the department of Surgery, University of North Carolina, United States and CT abdominal pelvic, from the Swedish National Infrastructure for Computing. The MR images contain around 109 datasets each of T1-FLASH, T2-Weighted, DTI and T1-MPRAGE. Significantly, visualization of human anatomical structure was achieved without prior segmentation. SurLens was adapted to visualize and display abnormalities, such as an indication of walderstrom's macroglobulinemia, stroke and penetrating brain injury in the human brain using Magentic Resonance (MR) images. Moreover, possible abnormalities in abdominal pelvic was also visualized using Computed Tomography (CT) slices. The study shows SurLens' functionality as

  20. [Polyplacophoran communities (Mollusca: Polyplacophora) at Bahia de La Paz, Baja California Sur, México].

    PubMed

    García Ríos, Cedar I; Alvarez Ruiz, Migdalia

    2007-03-01

    Eight species of polyplacophorans have been reported from La Bahia de la Paz, Baja California Sur, Mexico. We add Lepidochitona beanii, Chaetopleura lurida, Stenoplax limaciformis, S. mariposa, Lepidozona clathrata, L. serrata and Acanthochitona arragonites, increasing the known number of species to 15. Ordination analysis of five chiton communities at the site suggests a correlation of wave exposure to species composition and diversity: communities with intermediate wave exposure have more species (richness) and higher diversity (Shannon's index).

  1. [Polyplacophoran communities (Mollusca: Polyplacophora) at Bahia de La Paz, Baja California Sur, México].

    PubMed

    García Ríos, Cedar I; Alvarez Ruiz, Migdalia

    2007-03-01

    Eight species of polyplacophorans have been reported from La Bahia de la Paz, Baja California Sur, Mexico. We add Lepidochitona beanii, Chaetopleura lurida, Stenoplax limaciformis, S. mariposa, Lepidozona clathrata, L. serrata and Acanthochitona arragonites, increasing the known number of species to 15. Ordination analysis of five chiton communities at the site suggests a correlation of wave exposure to species composition and diversity: communities with intermediate wave exposure have more species (richness) and higher diversity (Shannon's index). PMID:18457125

  2. Electrical Resistivity Tomographies on the detection of adobe buried archaeological structures in Piramide Sur in Cahuachi (Peru)

    NASA Astrophysics Data System (ADS)

    Capozzoli, L.; Masini, N.; Rizzo, E.; Lasaponara, R.; Orefici, G.

    2012-04-01

    During the last two decades of excavations, adobe pyramids dating back from the 6th century B.C. to the 4th century A.D have been unearthed in the ancient Ceremonial Centre of Cahuachi near Nasca (Peru) by an Italian-Peruvian mission directed by Giuseppe Orefici. One of the archaeological sectors, called sector A, has been almost excavated and restored. To complete sector A only a terraced mound named "Piramide Sur" needs to be excavated. In order to provide useful information on the presence of buried structures and platforms as well on the geological stratigraphy a multi-scale approach based on the integration of satellite remote sensing with geophysical techniques was employed. Such investigations were carried out by the Italian mission ITACA, funded by the Italian Ministry Affairs and composed of researchers of two institutes of CNR (IMAA and IBAM), which provides a scientific support for archaeological research, since 2007. In particular, the subsurface features were investigated by Geoelectrical prospecting, performed by using a georesistivimeter for tomography which observe the resistivity value along sections. Several tomographies were carried out to investigate the shallow and deep structure of the pyramid both along the main flank at Nord and on the top. Finally, the integration of all data acquired by the different remote sensing techniques allowed for spatially characterizing the archaeological features, thus providing important information for the planning of the next archaeological campaign.

  3. Etude du stockage de l'hydrogene sur des nanostructures de carbone microporeuses

    NASA Astrophysics Data System (ADS)

    Poirier, Eric

    2007-12-01

    Le stockage de l'hydrogene par adsorption sur des adsorbants nano-structures a ete etudie sous differentes conditions de pression et de temperature. Les adsorbants etudies sont principalement des nanotubes de carbone a simple paroi ainsi que des structures metallo-organiques. Les mesures ont ete realisees a l'aide de systemes gravimetriques et volumetriques tres sensibles specialement mis au point pour de petits echantillons necessitant un degazage in situ. Les appareils developpes, au nombre de quatre, comprennent deux systemes gravimetriques et deux systemes volumetriques. Ensemble, ces systemes couvrent la plage de pressions (0-100) bars ainsi que la plage de temperatures (77-295) K. Les differentes analyses montrent que l'adsorption d'hydrogene sur les adsorbants nano-structures etudies est maximale a 77 K et varie entre environ (1.5 et 4) % masse. A temperature ambiante, l'adsorption croit lineairement avec la pression et demeure sous les 1% masse pour des pressions inferieures a 100 bars. L'adsorption d'hydrogene sur ces materiaux dans ces conditions se compare notamment a celle obtenue sur des charbons actives. La modelisation de l'adsorption a egalement ete realisee dans des conditions cryogeniques a l'aide du modele de Dubinin-Astakhov sous une forme adaptee pour l'adsorption supercritique. Les enthalpies d'adsorption calculees a partir de ce modele varient sous les 6 kJ/mole et sont donc consistantes avec des processus de physisorption. L'applicabilite du modele de Dubinin-Astakhov suggere que l'adsorption d'hydrogene puisse etre representee par un processus de remplissage des pores par un pseudo-liquide. Ces travaux s'inscrivent dans un contexte ou la capacite d'adsorption reelle des nanostructures de carbone est sujette a la controverse. En consequence, l'approche experimentale adoptee se distingue par les differentes demarches mises de l'avant pour l'obtention de mesures fiables sur des echantillons de faibles masses ainsi que par son caractere

  4. Mechanisms of anticonvulsant and sedative actions of the ethanolic stem-bark extract of Ficus sur Forssk (Moraceae) in rodents.

    PubMed

    Ishola, Ismail O; Olayemi, Sunday O; Yemitan, Omoniyi K; Ekpemandudiri, Ngozi K

    2013-11-01

    Ficus sur Forssk (Moraceae) is used in traditional African medicine in the treatment of epilepsy, pain and inflammations. Anticonvulsant activity was investigated using picrotoxin (PTX), strychnine (SCN), isoniazid (INZ), pentylenetetrazole (PTZ) and N-methyl-D-aspartic acid NMDA models of convulsion. The phytochemical analysis of the extract revealed the presence of flavonoids, saponins, tannins, alkaloids and anthraquinone. Oral administration of Ficus sur, 1 h before intraperitoneal injection of chemical convulsants significantly (p < 0.05) delayed the onset and prolonged the duration of convulsions in PTX, SCN, INZ, PTZ and NMDA-induced seizures. However, the anticonvulsant activity of the ethanolic extract of Ficus sur was significantly reversed following intraperitoneal pre-treatment with flumazenil (GABA receptor antagonist), cyproheptadine (5-HT2 receptor antagonist) and L-NNA (nitric oxide synthase inhibitor) in picrotoxin-induced convulsion. The data obtained suggest that ethanol extract of Ficus sur possessed significant anticonvulsant effect, thereby confirming the traditional uses of Ficus sur in the treatment of epilepsies; mechanisms of which could involve interaction with GABAergic, glycinergic, serotonergic and glutaminergic system barks.

  5. Phenylephrine preconditioning in embryonic heart H9c2 cells is mediated by up-regulation of SUR2B/Kir6.2: A first evidence for functional role of SUR2B in sarcolemmal KATP channels and cardioprotection.

    PubMed

    Jovanović, Sofija; Ballantyne, Thomas; Du, Qingyou; Blagojević, Miloš; Jovanović, Aleksandar

    2016-01-01

    ATP-sensitive K(+) (KATP) channels were originally described in cardiomyocytes, where physiological levels of intracellular ATP keep them in a closed state. Structurally, these channels are composed of pore-forming inward rectifier, Kir6.1 or Kir6.2, and a regulatory, ATP-binding subunit, SUR1, SUR2A or SUR2B. SUR1 and Kir6.2 form pancreatic type of KATP channels, SUR2A and Kir6.2 form cardiac type of KATP channels, SUR2B and Kir6.1 form vascular smooth muscle type of KATP channels. The presence of SUR2B has been described in cardiomyocytes, but its functional significance and role has remained unknown. Pretreatment with phenylephrine (100nM) for 24h increased mRNA levels of SUR2B and Kir6.2, without affecting those levels of SUR1, SUR2A and Kir6.1 in embryonic heart H9c2 cells. Such increase was associated with increased K(+) current through KATP channels and Kir6.2/SUR2B protein complexes as revealed by whole cell patch clamp electrophysiology and immunoprecipitation/Western blotting respectively. Pretreatment with phenylephrine (100nM) generated a cellular phenotype that acquired resistance to chemical hypoxia induced by 2,4-dinitrophenol (DNP; 10mM), which was accompanied by increased in K(+) current in response to DNP (10mM). Cytoprotection afforded by phenylephrine (100nM) was abolished by infection of H9c2 cells with adenovirus containing Kir6.2AFA, a mutant form of Kir6.2 with largely reduced K(+) conductance. Taking all together, the present findings demonstrate that the activation of α1-adrenoceptors up-regulates SUR2B/Kir6.2 to confer cardioprotection. This is the first account of possible physiological role of SUR2B in cardiomyocytes.

  6. Etude sur les tendons en materiaux composites et leur application aux ancrages postcontraints

    NASA Astrophysics Data System (ADS)

    Chennouf, Adil

    L'objectif general de la presente these est d'evaluer le comportement a l'arrachement et au fluage d'ancrages injectes constitues de tendons en materiaux composites afin d'etablir des recommandations plus appropriees et realistes pour le dimensionnement et la conception. Quatre types de tendons en materiaux composites, deux a base de fibres d'aramide et deux a base de fibres de carbone, ont ete utilises dans l'etude. Les travaux de recherche de cette these ont porte notamment sur: (I) Une caracterisation physique et mecanique des tendons en materiaux composites utilises dans l'etude. (II) Une etude en laboratoire sur les coulis de scellement. La premiere etape de cette etude a concerne le developpement d'un coulis de scellement performant adapte aux tendons en materiaux composites et a differentes situations d'injection. La seconde etape a traite des essais de caracterisations physique et mecanique du coulis de scellement developpe comparativement a trois coulis de scellement usuels d'un meme rapport E/L de 0,4. (III) Une etude sur des modeles reduits d'ancrages injectes. (IV) Une etude sur des modeles d'ancrages a grande echelle. La synthese de ces etudes a permis d'enoncer les principales conclusions suivantes: (1) Les valeurs moyennes des charges de rupture des tendons en materiaux composites ont ete de 1% a 29% superieures a celles specifiees par les manufacturiers. (2) L'etude sur les coulis de scellement a permis le developpement de coulis de ciment repondant aux criteres fixes, soient une grande stabilite, une bonne fluidite, une legere expansion et de bonnes caracteristiques mecaniques. (3) Les tendons en materiaux composites ont montre des contraintes d'adherence maximum superieures a celles des tendons en acier. (4) Le type de fibre, la configuration et le fini de surface des tendons en materiaux composites gouvernent leur resistance a l'adherence. (5) L'introduction de sable et d'autres ajouts comme les fines de silice et la poudre d'aluminium au coulis

  7. SUR2 subtype (A and B)-dependent differential activation of the cloned ATP-sensitive K+ channels by pinacidil and nicorandil

    PubMed Central

    Shindo, Takashi; Yamada, Mitsuhiko; Isomoto, Shojiro; Horio, Yoshiyuki; Kurachi, Yoshihisa

    1998-01-01

    The classical ATP sensitive K+ (KATP) channels are composed of a sulphonylurea receptor (SUR) and an inward rectifying K+ channel subunit (BIR/Kir6.2). They are the targets of vasorelaxant agents called K+ channel openers, such as pinacidil and nicorandil.In order to examine the tissue selectivity of pinacidil and nicorandil, in vitro, we compared the effects of these agents on cardiac type (SUR2A/Kir6.2) and vascular smooth muscle type (SUR2B/Kir6.2) of the KATP channels heterologously expressed in HEK293T cells, a human embryonic kidney cell line, by using the patch-clamp method.In the cell-attached recordings (145 mM K+ in the pipette), pinacidil and nicorandil activated a weakly inwardly-rectifying, glibenclamide-sensitive 80 pS K+ channel in both the transfected cells.In the whole-cell configuration, pinacidil showed a similar potency in activating the SUR2B/Kir6.2 and SUR2A/Kir6.2 channels (EC50 of ∼2 and ∼10 μM, respectively). On the other hand, nicorandil activated the SUR2B/Kir6.2 channel >100 times more potently than the SUR2A/Kir6.2 (EC50 of ∼10 μM and >500 μM, respectively).Thus, nicorandil, but not pinacidil, preferentially activates the KATP channels containing SUR2B. Because SUR2A and SUR2B are diverse only in 42 amino acids at their C-terminal ends, it is strongly suggested that this short part of SUR2B may play a critical role in the action of nicorandil on the vascular type classical KATP channel. PMID:9692785

  8. ATP-sensitive K(+) channels (Kir6.1/SUR1) regulate gap junctional coupling in cochlear-supporting cells.

    PubMed

    Blödow, Alexander; Begandt, Daniela; Bader, Almke; Becker, Annegret; Burghard, Alice; Kühne, Daniela; Kral, Andrej; Ngezahayo, Anaclet

    2016-07-01

    Using the double whole-cell patch-clamp technique, we found that the absence of intracellular ATP led to gap junction uncoupling in cochlear-supporting Hensen cells. The uncoupling was observed as a progressive reduction of the gap junctional electrical conductance from a starting value of approximately 40 nS to less than 0.04 nS within 10-20 min. The conductance rundown was partly avoided by at least 3 mM ATP and completely suppressed by 5 mM ATP or 5'-adenylyl-imidodiphosphate (AMP-PNP), the non-hydrolysable ATP analog, in the pipette filling solution, suggesting that ATP was needed as ligand and not as a hydrolysable energy supplier or substrate for enzymatic reactions. The effect of intracellular ATP was mimicked by the external application of barium, a nonselective blocker of inwardly rectifying K(+) (Kir) channels, and glibenclamide, an inhibitor of the ATP-sensitive Kir channels (KATP). Moreover a Ba(2+)-sensitive whole-cell inward current was observed in absence of internal ATP. We propose that the internal ATP kept the KATP channels in a closed state, thereby maintaining the gap junction coupling of Hensen cells. The immunostaining of guinea pig cochlear tissue revealed for the first time the expression of the KATP channel subunits Kir6.1 and SUR1 in Hensen cells and supported the proposed hypothesis. The results suggest that KATP channels, as regulator of the gap junction coupling in Hensen cells, could be the physiological link between the metabolic state of the supporting cells and K(+) recycling in the organ of Corti. PMID:27030354

  9. ATP-sensitive K(+) channels (Kir6.1/SUR1) regulate gap junctional coupling in cochlear-supporting cells.

    PubMed

    Blödow, Alexander; Begandt, Daniela; Bader, Almke; Becker, Annegret; Burghard, Alice; Kühne, Daniela; Kral, Andrej; Ngezahayo, Anaclet

    2016-07-01

    Using the double whole-cell patch-clamp technique, we found that the absence of intracellular ATP led to gap junction uncoupling in cochlear-supporting Hensen cells. The uncoupling was observed as a progressive reduction of the gap junctional electrical conductance from a starting value of approximately 40 nS to less than 0.04 nS within 10-20 min. The conductance rundown was partly avoided by at least 3 mM ATP and completely suppressed by 5 mM ATP or 5'-adenylyl-imidodiphosphate (AMP-PNP), the non-hydrolysable ATP analog, in the pipette filling solution, suggesting that ATP was needed as ligand and not as a hydrolysable energy supplier or substrate for enzymatic reactions. The effect of intracellular ATP was mimicked by the external application of barium, a nonselective blocker of inwardly rectifying K(+) (Kir) channels, and glibenclamide, an inhibitor of the ATP-sensitive Kir channels (KATP). Moreover a Ba(2+)-sensitive whole-cell inward current was observed in absence of internal ATP. We propose that the internal ATP kept the KATP channels in a closed state, thereby maintaining the gap junction coupling of Hensen cells. The immunostaining of guinea pig cochlear tissue revealed for the first time the expression of the KATP channel subunits Kir6.1 and SUR1 in Hensen cells and supported the proposed hypothesis. The results suggest that KATP channels, as regulator of the gap junction coupling in Hensen cells, could be the physiological link between the metabolic state of the supporting cells and K(+) recycling in the organ of Corti.

  10. Intragenic single nucleotide polymorphism haplotype analysis of SUR1 mutations in familial hyperinsulinism.

    PubMed

    Glaser, B; Furth, J; Stanley, C A; Baker, L; Thornton, P S; Landau, H; Permutt, M A

    1999-01-01

    Familial hyperinsulinism (HI; MIM# 256450) is an autosomal recessive disorder of pancreatic beta-cell function, characterized by inadequate suppression of insulin secretion despite severe recurrent fasting hypoglycemia. Subtotal pancreatectomy is frequently required to prevent permanent neurologic sequelae. The incidence of HI in the Caucasian population is estimated at 1:50,000, however an apparent increased incidence among Ashkenazi Jews and Saudi Arabian Arabs has been reported. A locus for HI was assigned by linkage analyses to human chromosome 11p15.1. The sulfonylurea receptor (MIM# 600509, SUR1) and the potassium channel, inwardly rectifying, subfamily J member 11 (MIM# 600937, KIR6.2) genes, 2 components of the beta-cell K(ATP) channel, are clustered in this chromosomal region, and mutations in these genes have been implicated in HI. We previously demonstrated that two mutations in the SUR1 gene are present on approximately 88% of HI-associated chromosomes in Ashkenazi Jewish patients. Haplotype analysis with microsatellite markers flanking the gene revealed that one mutation (delF1388), reported only in Ashkenazi probands, occurred on two related extended haplotypes. By contrast, the second, more common mutation (3992-9g-->a) was associated with nine different intergenic haplotypes and has been reported in non-Jewish HI patients as well. In this study, we evaluated disease-associated chromosomes from 41 Ashkenazi Jewish and 2 non-Jewish HI patients carrying the 3992-9g-->a mutation by assessing haplotypes defined by nine common single nucleotide polymorphisms (SNPs), six in the SUR1 gene, and three in the KIR6.2 gene. Our results indicate that all 54 chromosomes carrying the 3992-9g-->a mutation in the Jewish patients appear to have originated from one founder mutation, whereas the same mutation on chromosomes from non-Jewish patients originated independently. Furthermore, our findings have implications concerning the HI-associated chromosomes on which no

  11. Observation Station

    ERIC Educational Resources Information Center

    Rutherford, Heather

    2011-01-01

    This article describes how a teacher integrates science observations into the writing center. At the observation station, students explore new items with a science theme and use their notes and questions for class writings every day. Students are exposed to a variety of different topics and motivated to write in different styles all while…

  12. Instrumentation pour la spectroscopie laser sur faisceau d'ions rapides

    NASA Astrophysics Data System (ADS)

    Bazin, Marc

    Devant l'emergence des technologies exploitant l'infiniment petit, la spectroscopie atomique et moleculaire devient de plus en plus incontournable pour comprendre precisement les mecanismes quantiques impliques dans l'interaction des molecules. C'est le cas notamment de la nanotechnologie, de la dynamique reactionnelle des gaz a effet de serre ou simplement de l'identification des molecules constituant certains objets de l'astrophysique. Bien qu'un travail considerable soit deja accompli pour comprendre la dissociation ou la formation des molecules simples, il reste a vaincre la complexite des mecanismes impliques lorsque les molecules possedent plus de trois noyaux. Parmi les rares techniques de spectroscopie a tres haute resolution (jusqu'a la structure hyperfine), la spectroscopie laser sur faisceaux d'ions rapides est une methode experimentale eprouvee depuis trois decennies environ. Cette methode spectroscopique fournit des resultats comptant parmi les meilleurs pour obtenir des constantes moleculaires precises et permettre la reduction du spectre moleculaire. Une particularite remarquable de notre instrument est la possibilite d'enregistrer le signal de fragmentation moleculaire par laser via les etats de predissociation de la molecule etudiee. Notre contribution a ete d'ameliorer et de moderniser l'equipement existant. Nous avons augmente la resolution spectrale de notre instrument. Nous avons atteint notre principal objectif, a savoir, la possibilite d'acquerir des spectres selon deux modes : par detection du signal synchronisee sur le faisceau laser module en frequence ou par detection du signal directement par comptage. Cette derniere methode est une premiere sur ce type d'instrument et son principal interet a ete d'obtenir une meilleure mesure de l'elargissement de raie. Nous sommes parvenus a mettre clairement en evidence l'elargissement de raie avec la puissance laser en utilisant la methode de detection par comptage direct. La fluorescence induite par

  13. Traumatismes fermés et pénétrants de l'abdomen: analyse rétrospective sur 175 cas et revue de la littérature

    PubMed Central

    Fanomezantsoa, Raherinantenaina; Davidà, Rakotomena Solonirina; Tianarivelo, Rajaonarivony; Fabienne, Rabetsiahiny Lalao; Aina, Rajaonanahary Toky Mamin'Ny; Auberlin, Rakototiana Felantsoa; Allen, Hunald Francis; Nirina, Rakoto Ratsimba Hery

    2015-01-01

    Les traumatismes abdominaux sont relativement fréquents mais graves dans les pays en développement. Le but de cette étude était de décrire les aspects épidémiologiques, diagnostiques, thérapeutiques et évolutifs des contusions et plaies pénétrantes de l'abdomen prises en charge dans un pays à faibles ressources. Patients et méthodes: Il s'agissait d'une étude rétrospective et descriptive de 2 ans (2011-2012) ayant colligé 175 cas de traumatisés abdominaux au CHU-JRA Tananarive Madagascar. Parmi ces blessés (144 hommes et 31 femmes), il existait 122 vivants (69,7%) et 53 décès (30,3%) avant tout geste thérapeutique hospitalier. Les étiologies étaient dominées par les accidents à responsabilité civile (52,5%) et de la voie publique (38,5%). Les contusions et plaies pénétrantes représentaient respectivement 41,8% et 58,2%. Parmi les blessés vivants, 112 ont été opérés (91,8%). L’évolution hospitalière était favorable dans 94,3%. Quatre patients avaient des suites opératoires compliquées (3,6%). Sept patients étaient décédés (5,7%). Parmi les décès préhospitaliers, nous avons observé 73,6% de polytraumatisme (n = 39) et 26,4% de traumatismes abdominaux isolés (n = 14). A l'autopsie, les lésions abdominales étaient hémorragiques dans 94,3% incluant des plaies vasculaires rétropéritonéales, des ruptures hépatospléniques et des traumatismes graves du bassin. En situation précaire, les traumatismes abdominaux ont une mortalité préhospitalière assez importante. A l'hôpital, l’évolution était généralement favorable au prix d'un acte opératoire invasif. PMID:26097633

  14. Mesure et retroaction sur un qubit multi-niveaux en electrodynamique quantique en circuit non lineair

    NASA Astrophysics Data System (ADS)

    Boissonneault, Maxime

    L'electrodynamique quantique en circuit est une architecture prometteuse pour le calcul quantique ainsi que pour etudier l'optique quantique. Dans cette architecture, on couple un ou plusieurs qubits supraconducteurs jouant le role d'atomes a un ou plusieurs resonateurs jouant le role de cavites optiques. Dans cette these, j'etudie l'interaction entre un seul qubit supraconducteur et un seul resonateur, en permettant cependant au qubit d'avoir plus de deux niveaux et au resonateur d'avoir une non-linearite Kerr. Je m'interesse particulierement a la lecture de l'etat du qubit et a son amelioration, a la retroaction du processus de mesure sur le qubit de meme qu'a l'etude des proprietes quantiques du resonateur a l'aide du qubit. J'utilise pour ce faire un modele analytique reduit que je developpe a partir de la description complete du systeme en utilisant principalement des transfprmations unitaires et une elimination adiabatique. J'utilise aussi une librairie de calcul numerique maison permettant de simuler efficacement l'evolution du systeme complet. Je compare les predictions du modele analytique reduit et les resultats de simulations numeriques a des resultats experimentaux obtenus par l'equipe de quantronique du CEASaclay. Ces resultats sont ceux d'une spectroscopie d'un qubit supraconducteur couple a un resonateur non lineaire excite. Dans un regime de faible puissance de spectroscopie le modele reduit predit correctement la position et la largeur de la raie. La position de la raie subit les decalages de Lamb et de Stark, et sa largeur est dominee par un dephasage induit par le processus de mesure. Je montre que, pour les parametres typiques de l'electrodynamique quantique en circuit, un accord quantitatif requiert un modele en reponse non lineaire du champ intra-resonateur, tel que celui developpe. Dans un regime de forte puissance de spectroscopie, des bandes laterales apparaissent et sont causees par les fluctuations quantiques du champ electromagnetique

  15. Estimating effective roughness parameters of the L-MEB model for soil moisture retrieval using passive microwave observations from SMAPVEX12

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Although there have been efforts to improve existing soil moisture retrieval algorithms, the ability to estimate soil moisture from passive microwave observations is still hampered by problems in accurately modeling the observed microwave signal. This paper focuses on the estimation of effective sur...

  16. Whipple Observations

    NASA Astrophysics Data System (ADS)

    Trangsrud, A.

    2015-12-01

    The solar system that we know today was shaped dramatically by events in its dynamic formative years. These events left their signatures at the distant frontier of the solar system, in the small planetesimal relics that populate the vast Oort Cloud, the Scattered Disk, and the Kuiper Belt. To peer in to the history and evolution of our solar system, the Whipple mission will survey small bodies in the large volume that begins beyond the orbit of Neptune and extends out to thousands of AU. Whipple detects these objects when they occult distant stars. The distance and size of the occulting object is reconstructed from well-understood diffraction effects in the object's shadow. Whipple will observe tens of thousands of stars simultaneously with high observing efficiency, accumulating roughly a billion "star-hours" of observations over its mission life. Here we describe the Whipple observing strategy, including target selection and scheduling.

  17. Observing Insects.

    ERIC Educational Resources Information Center

    Arbel, Ilil

    1991-01-01

    Describes how to observe and study the fascinating world of insects in public parks, backyards, and gardens. Discusses the activities and habits of several common insects. Includes addresses for sources of beneficial insects, seeds, and plants. (nine references) (JJK)

  18. Pharmacology of human sulphonylurea receptor SUR1 and inward rectifier K+ channel Kir6.2 combination expressed in HEK-293 cells

    PubMed Central

    Gopalakrishnan, Murali; Molinari, Eduardo J; Shieh, Char-Chang; Monteggia, Lisa M; Roch, Jean-Marc; Whiteaker, Kristi L; Scott, Victoria E S; Sullivan, James P; Brioni, Jorge D

    2000-01-01

    The pharmacological properties of KATP channels generated by stable co-expression of the sulphonylurea receptor SUR1 and the inwardly rectifying K+ channel Kir6.2 were characterized in HEK-293 cells.[3H]-Glyburide (glibenclamide) bound to transfected cells with a Bmax value of 18.5 pmol mg−1 protein and with a KD value of 0.7 nM. Specific binding was displaced by a series of sulphonylurea analogues with rank order potencies consistent with those observed in pancreatic RINm5F insulinoma and in the brain.Functional activity of KATP channels was assessed by whole cell patch clamp, cation efflux and membrane potential measurements. Whole cell currents were detected in transfected cells upon depletion of internal ATP or by exposure to 500 μM diazoxide. The currents showed weak inward rectification and were sensitive to inhibition by glyburide (IC50=0.92 nM).Metabolic inhibition by 2-deoxyglucose and oligomycin treatment triggered 86Rb+ efflux from transfected cells that was sensitive to inhibition by glyburide (IC50=3.6 nM).Diazoxide, but not levcromakalim, evoked concentration-dependent decreases in DiBAC4(3) fluorescence responses with an EC50 value of 14.1 μM which were attenuated by the addition of glyburide. Diazoxide-evoked responses were inhibited by various sulphonylurea analogues with rank order potencies that correlated well with their binding affinities.In summary, results from ligand binding and functional assays demonstrate that the pharmacological properties of SUR1 and Kir6.2 channels co-expressed in HEK-293 cells resemble those typical of native KATP channels described in pancreatic and neuronal tissues. PMID:10742287

  19. Effet de la composition des materiaux composites sur la caracterisation et detection par ondes de Lamb

    NASA Astrophysics Data System (ADS)

    Ostiguy, Pierre-Claude

    Les matériaux composites sont de plus en plus utilisés en aéronautique. Leurs excellentes propriétés mécaniques et leur faible poids leur procurent un avantage certain par rapport aux matériaux métalliques. Ceux-ci étant soumis à diverses conditions de chargement et environnementales, ils sont suceptibles de subir plusieurs types d'endommagements, compromettant leur intégrité. Des méthodes fiables d'inspection sont donc nécessaires pour évaluer leur intégrité. Néanmoins, peu d'approches non destructives, embarquées et efficaces sont présentement utilisées. Ce travail de recherche se penche sur l'étude de l'effet de la composition des matériaux composites sur la détection et la caractérisation par ondes guidées. L'objectif du projet est de développer une approche de caractérisation mécanique embarquée permettant d'améliorer la performance d'une approche d'imagerie par antenne piézoélectriques sur des structures composite et métalliques. La contribution de ce projet est de proposer une approche embarquée de caractérisation mécanique par ultrasons qui ne requiert pas une mesure sur une multitude d'échantillons et qui est non destructive. Ce mémoire par articles est divisé en quatre parties, dont les parties deux A quatre présentant les articles publiés et soumis. La première partie présente l'état des connaissances dans la matière nécessaires à l'acomplissement de ce projet de maîtrise. Les principaux sujets traités portent sur les matériaux composites, propagation d'ondes, la modélisation des ondes guidées, la caractérisation par ondes guidées et la surveillance embarquée des structures. La deuxième partie présente une étude de l'effet des propriétés mécaniques sur la performance de l'algorithme d'imagerie Excitelet. L'étude est faite sur une structure isotrope. Les résultats ont démontré que l'algorithme est sensible à l'exactitude des propriétés mécaniques utilisées dans le modèle. Cette

  20. Les enjuex éthiques entourant la recherche en santé sur les enfants

    PubMed Central

    2008-01-01

    RÉSUMÉ La recherche en santé est un devoir moral parce qu’elle est la base des soins probants prodigués par tous les dispensateurs de soins. Des politiques et des règlements précis régissent la tenue des recherches sur des humains. Il faut procéder à une évaluation éthique d’un projet de recherche donné avant de pouvoir l’entreprendre. La recherche sur les enfants pose d’énormes défis en matière de consentement éclairé et d’assentiment, de vulnérabilité et de potentiel de conflit d’intérêts (CDI). Les chercheurs en santé pédiatrique devraient prôner la participation des enfants à la recherche, tout en se montrant attentifs à en limiter les risques.

  1. Adsorption de gaz sur les materiaux microporeux modelisation, thermodynamique et applications

    NASA Astrophysics Data System (ADS)

    Richard, Marc-Andre

    2009-12-01

    Nos travaux sur l'adsorption de gaz dans les materiaux microporeux s'inscrivent dans le cadre des recherches visant a augmenter l'efficacite du stockage de l'hydrogene a bord des vehicules. Notre objectif etait d'etudier la possibilite d'utiliser l'adsorption afin d'ameliorer l'efficacite de la liquefaction de l'hydrogene des systemes a petite echelle. Nous avons egalement evalue les performances d'un systeme de stockage cryogenique de l'hydrogene base sur la physisorption. Comme nous avons affaire a des plages de temperatures particulierement etendues et a de hautes pressions dans la region supercritique du gaz, nous avons du commencer par travailler sur la modelisation et la thermodynamique de l'adsorption. La representation de la quantite de gaz adsorbee en fonction de la temperature et de la pression par un modele semi-empirique est un outil utile pour determiner la masse de gaz adsorbee dans un systeme mais egalement pour calculer les effets thermiques lies a l'adsorption. Nous avons adapte le modele Dubinin-Astakhov (D-A) pour modeliser des isothermes d'adsorption d'hydrogene, d'azote et de methane sur du charbon actif a haute pression et sur une grande plage de temperatures supercritiques en considerant un volume d'adsorption invariant. Avec cinq parametres de regression (incluant le volume d'adsorption Va), le modele que nous avons developpe permet de tres bien representer des isothermes experimentales d'adsorption d'hydrogene (de 30 a 293 K, jusqu'a 6 MPa), d'azote (de 93 a 298 K, jusqu'a 6 MPa) et de methane (de 243 a 333 K, jusqu'a 9 MPa) sur le charbon actif. Nous avons calcule l'energie interne de la phase adsorbee a partir du modele en nous servant de la thermodynamique des solutions sans negliger le volume d'adsorption. Par la suite, nous avons presente les equations de conservation de la niasse et de l'energie pour un systeme d'adsorption et valide notre demarche en comparant des simulations et des tests d'adsorption et de desorption. En plus de l

  2. The optimization research of the multi-response problems based on the SUR.

    PubMed

    Su, Haitao; Yao, Hong Mei; Zeng, Hui

    2015-03-01

    In the optimization design of products and processes in the biological medicine, we need to consider multiple characteristics of quality simultaneously, namely multi-response problems, multi-response optimization design can improve the quality of the products effectively, and realize enormous economic benefits and so multi-response optimization design is showing a more and more important role in continuous quality improvement activities. But usually there is no specific set of input variables to make all the response variables be optimal, and the traditional multi-response surface method cannot solve the correlation problem between multi-responses and regression model problem effectively. Because we can make a better fitting model and solve the problem of the correlation between the response variables at the same time with SUR method, this thesis uses the SUR method to model the relationship between each response and control variables, and makes predictions; confirms the satisfaction function of each response and the overall satisfaction function; combines with practical problems of a company in biological medicine field named SX to conduct empirical research, this thesis confirms the optimal factor level combination with the overall satisfaction function in the end, thus solves the multi-response optimization problems.

  3. Volvulus du grêle sur paquet d’ascaris: à propos d’un cas

    PubMed Central

    Diouf, Cheikh; Kane, Ahmed; Ndoye, Ndeye Aby; Ndour, Oumar; Faye-Fall, Aimé Lakh; Fall, Mbaye; Alumeti, Désiré Munyali; Ngom, Gabriel

    2016-01-01

    Nous rapportons un cas exceptionnel de volvulus nécrosé de l'intestin grêle dû à des ascaris adultes chez un enfant de 7 ans. A l'admission, l'enfant présentait le tableau d'occlusion intestinale qui évoluait depuis deux jours avec altération de l'état général. La radiographie de l'abdomen sans préparation retrouvait des niveaux hydroaériques de type grêlique et un aspect tigré évoquant le diagnostic d'une occlusion intestinale haute sur masse abdominale. Après la réanimation, le traitement chirurgical consistait en une laparotomie qui avait retrouvé un volvulus nécrosé de l'iléon terminale contenant des ascaris adultes. Une résection du grêle sur environ un mètre emportant le segment nécrosé suivie d'une iléostomie était réalisée. L'évolution a été favorable, l'anastomose iléo-colique fut réalisée quatre semaines plus tard. Au recul de deux ans l'enfant est indemne de tout symptôme. PMID:27795803

  4. Visual Analysis and Dissemination of Scientific Literature Collections with SurVis.

    PubMed

    Beck, Fabian; Koch, Sebastian; Weiskopf, Daniel

    2016-01-01

    Bibliographic data such as collections of scientific articles and citation networks have been studied extensively in information visualization and visual analytics research. Powerful systems have been built to support various types of bibliographic analysis, but they require some training and cannot be used to disseminate the insights gained. In contrast, we focused on developing a more accessible visual analytics system, called SurVis, that is ready to disseminate a carefully surveyed literature collection. The authors of a survey may use our Web-based system to structure and analyze their literature database. Later, readers of the survey can obtain an overview, quickly retrieve specific publications, and reproduce or extend the original bibliographic analysis. Our system employs a set of selectors that enable users to filter and browse the literature collection as well as to control interactive visualizations. The versatile selector concept includes selectors for textual search, filtering by keywords and meta-information, selection and clustering of similar publications, and following citation links. Agreement to the selector is represented by word-sized sparkline visualizations seamlessly integrated into the user interface. Based on an analysis of the analytical reasoning process, we derived requirements for the system. We developed the system in a formative way involving other researchers writing literature surveys. A questionnaire study with 14 visual analytics experts confirms that SurVis meets the initially formulated requirements.

  5. Evaluation des connaissances des parents sur les bronchiolites aiguës

    PubMed Central

    Gueddari, Widad; Tazi, Abderrahmane; Ouardi, Amine; Nani, Samira; Zineddine, Abdelhadi

    2014-01-01

    Les infections respiratoires (IR) constituent la deuxième cause de mortalité infantile au Maroc, dû en partie à l'absence d'information et de sensibilisation. Le but de ce travail était d’évaluer les connaissances des parents sur la bronchiolite aiguë, infection respiratoire très fréquente. Nous avons réalisé une enquête basée sur un questionnaire, auprès de parents de nourrissons consultants pour toux, avec ou sans gêne respiratoire. 180 parents ont été inclus dans l’étude. Les parents pensaient que l'infection respiratoire était secondaire au climat froid (96%); seuls 4% ont évoqué une origine infectieuse. Aucun des parents ne savait que le lavage des mains était un moyen de prévention de la transmission. Les parents ont majoritairement répondu que la kinésithérapie respiratoire ne servait à rien (65%), et qu'elle était nocive (24.5%). Ce manque de connaissances fondamentales en matière d'IR et de bronchiolite en particulier, devrait inciter à entreprendre un programme de sensibilisation PMID:25328606

  6. Implementation of tsunami disaster prevention measures in the municipality of San Rafael del Sur, Nicaragua

    NASA Astrophysics Data System (ADS)

    Strauch, W.; Talavera, E.; Acosta, N.; Sanchez, M.; Mejia, E.

    2007-05-01

    The Nicaraguan Pacific coast presents considerable tsunami risk. On September 1, 1992, a tsunami caused enormous damage in the infrastructure and killed more than 170 people. A pilot project was conducted between 2006 and 2007 in the municipality of San Rafel del Sur, area of Masachapa, The project included multiple topics of tsunami prevention measures and considering the direct participation of the local population, as: -General education on disaster prevention, participative events; -Investigation of awareness level and information needs for different population groups; -Specific educational measures in the schools; -Publication of brochures, calendars, news paper articles, radio programs, TV spots -Development of local tsunami hazard maps, 1:5,000 scale; (based on previous regional tsunami hazard mapping projects and local participation) -Development of a tsunami warning plan; -Improvements of the national tsunami warning system. -Installation of sirens for tsunami warning -Installation of tsunami signs, indicating hazardous areas, evacuation routes, safe places; -Realization of evacuation drills in schools. Based on the experiences gained in Masachapa it is planned to run similar projects in other areas along the Nicaraguan Pacific coast. In the project participated the local municipality and local stakeholders of San Rafael del Sur, Ministry of Education, National Police, Nicaraguan Red Cross, Ministry of Health, Ministry of Tourism, Nicaraguan Geosciences Institute (INETER), National System for Disaster Prevention (SINAPRED), Swiss Agency for Development and Cooperation (SDC). It was financed by SDC and INETER.

  7. Cancer du sein sur tissu mammaire ectopique: à propos de 2 cas

    PubMed Central

    Haddad, Houssam; Bourhaleb, Zouhour; El Harroudi, Tijani; Mezouar, Loubna; El Hfid, Mohamed

    2012-01-01

    Le cancer du sein sur tissu mammaire ectopique est une tumeur rare qui représente 0,2 à 0,6% de l′ensemble des cancers du sein. Les auteurs en rapportent 2 cas pris en charge dans 2 centres d′oncologie marocains. Il s′agit de 2 patientes âgées de 31 ans et 47 ans présentant un cancer du sein sur tissu mammaire ectopique en situation axillaire. Une tumorectomie avec curage ganglionnaire axillaire homolatéral a été réalisée chez les 2 patientes dont une après une chimiothérapie néoadjuvante. Le traitement adjuvant a compris une chimiothérapie, radiothérapie puis une hormonothérapie. Après un recul de 12 mois et 20 mois respectivement, les 2 patientes sont en rémission complète. PMID:23330041

  8. Boron and strontium isotope compositions of groundwater from the La Paz arid coastal aquifer, Baja California Sur, Mexico

    NASA Astrophysics Data System (ADS)

    Mahlknecht, Jürgen; Rosner, Martin; Meixner, Anette

    2016-04-01

    In groundwater studies boron and strontium isotopic compositions can be used to identify natural and anthropogenic sources as well as processes related to groundwater recharge, flow and mixing. The La Paz arid costal aquifer in Baja California Sur, Mexico, is the most important source of drinking and irrigation water for La Paz area and suffers from anthropogenic contamination and intensive exploitation of the aquifer causing seawater intrusion and general groundwater abatement. The relatively un-radiogenic 87Sr/86Sr isotope ratios of the La Paz groundwater range in a narrow field between 0.7054 and 0.7062. In contrast to strontium the boron isotope composition displays a large variability between +27 and +55 permil d11B. The relatively low 87Sr/86Sr ratios of the La Paz groundwater highlight a significant contribution of strontium derived from local terrestrial sediments and igneous rocks with known 87Sr/86Sr ratios between 0.705 and 0.7035. The large variability of d11B values indicate that multiple sources and processes determine the boron isotope composition of La Paz groundwater. Rainwater (high d11B), seawater (~+40 permil) due to seawater intrusions, wastewater (low to medium d11B) and boron derived from the local geology (low to medium d11B) explain most of the observed groundwater d11B variability. However, d11B values higher than modern seawater point to significant boron isotope fractionation by preferential absorption of 10B onto clay minerals during the evolution of some groundwater samples. Due to low boron concentrations in rainwater a significant contribution of 11B-rich rainwater (>+40 permil) on the La Paz groundwater is unlikely.

  9. Arab observations

    NASA Astrophysics Data System (ADS)

    Fatoohi, L. J.

    There are two main medieval Arab sources of astronomical observations: chronicles and astronomical treatises. Medieval Arabs produced numerous chronicles many of which reported astronomical events that the chroniclers themselves observed or were witnessed by others. Astronomical phenomena that were recorded by chroniclers include solar and lunar eclipses, cometary apparitions, meteors, and meteor showers. Muslim astronomers produced many astronomical treatises known as zijes. Zijes include records of mainly predictable phenomena, such as eclipses of the Sun and Moon. Unlike chronicles, zijes usually ignore irregular phenomena such as the apparitions of comets and meteors, and meteor showers. Some zijes include astronomical observations, especially of eclipses. Not unexpectedly, records in zijes are in general more accurate than their counterparts in chronicles. However, research has shown that medieval Arab chronicles and zijes both contain some valuable astronomical observational data. Unfortunately, much of the heritage of medieval Arab chroniclers and astronomers is still in manuscript form. Moreover, most of the huge numbers of Arabic manuscripts that exist in various libraries, especially in Arab countries, are still uncatalogued. Until now there is only one catalogue of zijes which was compiled in the fifties and which includes brief comments on 200 zijes. There is a real need for systematic investigation of medieval Arab historical and astronomical manuscripts which exist in many libraries all over the world.

  10. Impact de la preparation des anodes crues et des conditions de cuisson sur la fissuration dans des anodes denses

    NASA Astrophysics Data System (ADS)

    Amrani, Salah

    La fabrication de l'aluminium est realisee dans une cellule d'electrolyse, et cette operation utilise des anodes en carbone. L'evaluation de la qualite de ces anodes reste indispensable avant leur utilisation. La presence des fissures dans les anodes provoque une perturbation du procede l'electrolyse et une diminution de sa performance. Ce projet a ete entrepris pour determiner l'impact des differents parametres de procedes de fabrication des anodes sur la fissuration des anodes denses. Ces parametres incluent ceux de la fabrication des anodes crues, des proprietes des matieres premieres et de la cuisson. Une recherche bibliographique a ete effectuee sur tous les aspects de la fissuration des anodes en carbone pour compiler les travaux anterieurs. Une methodologie detaillee a ete mise au point pour faciliter le deroulement des travaux et atteindre les objectifs vises. La majorite de ce document est reservee pour la discussion des resultats obtenus au laboratoire de l'UQAC et au niveau industriel. Concernant les etudes realisees a l'UQAC, une partie des travaux experimentaux est reservee a la recherche des differents mecanismes de fissuration dans les anodes denses utilisees dans l'industrie d'aluminium. L'approche etait d'abord basee sur la caracterisation qualitative du mecanisme de la fissuration en surface et en profondeur. Puis, une caracterisation quantitative a ete realisee pour la determination de la distribution de la largeur de la fissure sur toute sa longueur, ainsi que le pourcentage de sa surface par rapport a la surface totale de l'echantillon. Cette etude a ete realisee par le biais de la technique d'analyse d'image utilisee pour caracteriser la fissuration d'un echantillon d'anode cuite. L'analyse surfacique et en profondeur de cet echantillon a permis de voir clairement la formation des fissures sur une grande partie de la surface analysee. L'autre partie des travaux est basee sur la caracterisation des defauts dans des echantillons d'anodes crues

  11. Prevalence of infection with Toxoplasma gondii in landrace and mixed breed pigs slaughtered in Baja California Sur state, Mexico

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Purpose We performed a cross-sectional study to determine the seroprevalence of Toxoplasma gondii infection in 308 domestic pigs slaughtered in La Paz, Baja California Sur State, Mexico using the modified agglutination test (MAT, cut off 1:25). Results Forty (13%) of the 308 pigs were seropositive ...

  12. Effets de la pollution de l’air sur la santé

    PubMed Central

    Abelsohn, Alan; Stieb, Dave M.

    2011-01-01

    Résumé Objectif Faire connaître aux médecins de famille les effets de la pollution atmosphérique sur la santé et indiquer quels conseils donner aux patients vulnérables pour qu’ils soient moins exposés. Sources de l’information On a consulté MEDLINE à l’aide des termes relatifs à la pollution atmosphérique et à ses effets indésirables. On a révisé les articles en anglais publiés entre janvier 2008 et décembre 2009. La plupart des études contenaient des preuves de niveau II. Principal message Au Canada, la pollution de l’air extérieur cause une morbidité et une mortalité importantes. Elle peut affecter le système respiratoire (exacerbation de l’asthme et de la maladie pulmonaire obstructive chronique) et le système cardiovasculaire (déclencher l’arythmie, l’insuffisance cardiaque et les AVC). La cote air santé (CAS) est un nouvel outil de communication mis au point par Santé Canada et Environnement Canada qui indique sur une échelle de 1 à 10, le risque pour la santé causé par la pollution atmosphérique. La CAS est largement diffusée dans les médias et cet outil pourrait être utile au médecin de famille pour inciter les patients à haut risque (comme ceux qui souffrent d’asthme, de maladie pulmonaire obstructive chronique ou d’insuffisance cardiaque) à réduire leur exposition à la pollution atmosphérique. Conclusion Le médecin de famille peut se servir de la CAS et de ses messages sur la santé pour enseigner aux asthmatiques et aux autres patients à risque élevé la façon de réduire les risques pour la santé causés par la pollution atmosphérique.

  13. Late Cardiac Events after Childhood Cancer: Methodological Aspects of the Pan-European Study PanCareSurFup

    PubMed Central

    Feijen, Elizabeth A. M.; Font-Gonzalez, Anna; van Dalen, Elvira C.; van der Pal, Helena J. H.; Reulen, Raoul C.; Winter, David L.; Kuehni, Claudia E.; Haupt, Riccardo; Alessi, Daniela; Byrne, Julianne; Bardi, Edit; Jakab, Zsuzsanna; Grabow, Desiree; Garwicz, Stanislaw; Jankovic, Momcilo; Levitt, Gill A.; Skinner, Roderick; Zadravec Zaletel, Lorna; Hjorth, Lars; Tissing, Wim J. E.; de Vathaire, Florent; Hawkins, Mike M.; Kremer, Leontien C. M.

    2016-01-01

    Background and Aim Childhood cancer survivors are at high risk of long-term adverse effects of cancer and its treatment, including cardiac events. The pan-European PanCareSurFup study determined the incidence and risk factors for cardiac events among childhood cancer survivors. The aim of this article is to describe the methodology of the cardiac cohort and nested case-control study within PanCareSurFup. Methods Eight data providers in Europe participating in PanCareSurFup identified and validated symptomatic cardiac events in their cohorts of childhood cancer survivors. Data on symptomatic heart failure, ischemia, pericarditis, valvular disease and arrhythmia were collected and graded according to the Criteria for Adverse Events. Detailed treatment data, data on potential confounders, lifestyle related risk factors and general health problems were collected. Results The PanCareSurFup cardiac cohort consisted of 59,915 5-year childhood cancer survivors with malignancies diagnosed between 1940 and 2009 and classified according to the International Classification of Childhood Cancer 3. Different strategies were used to identify cardiac events such as record linkage to population/ hospital or regional based databases, and patient- and general practitioner-based questionnaires. Conclusion The cardiac study of the European collaborative research project PanCareSurFup will provide the largest cohort of 5-year childhood cancer survivors with systematically ascertained and validated data on symptomatic cardiac events. The result of this study can provide information to minimize the burden of cardiac events in childhood cancer survivors by tailoring the follow-up of childhood cancer survivors at high risk of cardiac adverse events, transferring this knowledge into evidence-based clinical practice guidelines and providing a platform for future research studies in childhood cancer patients.  PMID:27643694

  14. Ophthalmic Combination of SurR9-C84A and Trichostatin-A Targeting Molecular Pathogenesis of Alkali Burn

    PubMed Central

    Roy, Kislay; Sriramoju, Bhasker; Kanwar, Rupinder K.; Kanwar, Jagat R.

    2016-01-01

    Background: Alkali burn is a frequently occurring ocular injury that resembles ocular inflammation caused by eye allergies, infection, and refractive surgeries. Methods: We investigated the synergistic regenerative potential of dominant negative survivin mutant (SurR9-C84A) and histone deacetylase (HDAC) inhibitor trichostatin-A (TSA) against alkali burn and corneal haze using human keratocytes and rabbit alkali burn model (Female New Zealand white rabbits). Results: Combination of SurR9-C84A and TSA suppressed levels of transforming growth factor (TGF)-β, alpha smooth-muscle actin (α-SMA), fibronectin and HDAC1, leading to apoptosis in myofibroblast cells and, showed the potential to clear the corneal haze. An insult with 0.5 N NaOH for 1 min led to neutrophils infiltration and formation of large vacuoles in the stroma. Treatments with TSA and SurR9-C84A for 40 min led to improvement in the conjunctival and corneal tissue integrity, marked by an increase in clathrin, and claudin expressions. An increase in TGF-β and endogenous survivin confirmed wound healing and cell proliferation in rabbit cornea. The blood analysis revealed a substantial decrease in the RBC, WBC, platelets, or the hemoglobin content post alkali burn. The cytokine array analysis revealed that NaOH induced expressions of IL-1α and MMP-9, which were found to be significantly downregulated (1.8 and 11.5 fold respectively) by the combinatorial treatment of SurR9-C84A and TSA. Conclusion: Our results confirmed that combination of SurR9-C84A with TSA worked in synergy to heal ocular injury and inflammations due to alkali burn and led to the regeneration of ocular tissue by increasing clathrin, claudin, survivin, and TGF-β and reversal of alkali burn by suppressing IL-1α and MMP-9 without inducing haze. PMID:27516741

  15. The Periplasmic Bacterial Molecular Chaperone SurA Adapts Its Structure to Bind Peptides in Different Conformations to Assert a Sequence Preference for Aromatic Residues

    SciTech Connect

    Xu, X.; Wang, S.; Hu, Y.-X.; McKay, D.B.

    2009-06-04

    The periplasmic molecular chaperone protein SurA facilitates correct folding and maturation of outer membrane proteins in Gram-negative bacteria. It preferentially binds peptides that have a high fraction of aromatic amino acids. Phage display selections, isothermal titration calorimetry and crystallographic structure determination have been used to elucidate the basis of the binding specificity. The peptide recognition is imparted by the first peptidyl-prolyl isomerase (PPIase) domain of SurA. Crystal structures of complexes between peptides of sequence WEYIPNV and NFTLKFWDIFRK with the first PPIase domain of the Escherichia coli SurA protein at 1.3 A resolution, and of a complex between the dodecapeptide and a SurA fragment lacking the second PPIase domain at 3.4 A resolution, have been solved. SurA binds as a monomer to the heptapeptide in an extended conformation. It binds as a dimer to the dodecapeptide in an alpha-helical conformation, predicated on a substantial structural rearrangement of the SurA protein. In both cases, side-chains of aromatic residues of the peptides contribute a large fraction of the binding interactions. SurA therefore asserts a recognition preference for aromatic amino acids in a variety of sequence configurations by adopting alternative tertiary and quaternary structures to bind peptides in different conformations.

  16. Experiential environmental learning: A case study of innovative pedagogy in Baja Sur, Mexico

    NASA Astrophysics Data System (ADS)

    Schneller, Andrew Jon

    This mixed methods case study describes an innovative two-semester middle school environmental learning course that departs from traditional Mexican expository pedagogy through the incorporation of experiential and service learning. This research takes place in a small middle school in Pescadero, Baja California Sur, Mexico. The research approach utilized in the study adds to the handful of studies in this cross-disciplinary field by employing quantitative methodologies to measure course outcomes on student environmental knowledge, perceptions, and actions, while simultaneously qualitatively describing the behavioral, educational, environmental, and social experiences of students. This research employs Dewey's theories of experience---as well as those of more contemporary authenticity theorists---in order to identify the philosophies that advocate incorporating experiential pedagogy within the curriculum. Implications for Mexican educational policy, practical pedagogical applications, and theory are discussed.

  17. Metal concentrations in demersal fish species from Santa Maria Bay, Baja California Sur, Mexico (Pacific coast).

    PubMed

    Jonathan, M P; Aurioles-Gamboa, David; Villegas, Lorena Elizabeth Campos; Bohórquez-Herrera, Jimena; Hernández-Camacho, Claudia J; Sujitha, S B

    2015-10-15

    Concentrations of 11 trace metals (Fe, Mn, Cr, Cu, Ni, Co, Pb, Zn, Cd, As, Hg) in 40 fish species from Santa Maria Bay, Baja California Sur, Mexico, the strategically important area for marine mammals and organisms were analyzed. Based on their concentrations the ranking of metals Fe>Zn>Ni>Cr>Mn>Pb>Cu>Co>As>Cd>Hg suggests that organism size, metabolism and feeding habits are correlated with metal concentrations. Local geological formations affect the concentrations of different metals in the aquatic environment and are subsequently transferred to fishes. The correlation analysis suggests that metabolism and nurturing habits impact the concentration of metals. Concentrations of Fe and Mn appear to be influenced by scavenging and absorption processes, which vary by species. The considerable variability in the metal concentrations obtained in different species underscores the importance of regular monitoring.

  18. Recommandations sur l’examen pelvien de dépistage systématique

    PubMed Central

    Tonelli, Marcello; Gorber, Sarah Connor; Moore, Ainsley; Thombs, Brett D.

    2016-01-01

    Résumé Objectif Examiner les lignes directrices de 2014 de l’American College of Physicians (ACP) en matière d’examens pelviens de dépistage du cancer (autre que du col), des maladies inflammatoires pelviennes ou d’autres affections gynécologiques bénignes afin de déterminer si les lignes directrices de l’ACP en matière d’examens pelviens systématiques sont conformes aux normes établies par le Groupe d’étude canadien sur les soins de santé préventifs (GECSSP) et peuvent être adaptées ou adoptées. Méthodologie La méthode SNAP-IT (Smooth National Adaptation and Presentation of Guidelines to Improve Thrombosis Treatment) a servi à déterminer si les lignes directrices de l’ACP étaient conformes aux normes du GECSSP et pouvaient être adaptées ou adoptées. Recommandations Le GECSSP recommande de ne pas effectuer un examen pelvien de dépistage des cancers non cervicaux, des maladies inflammatoires pelviennes ou d’autres affections gynécologiques chez les femmes asymptomatiques. Il s’agit d’une forte recommandation reposant sur des données probantes de qualité modérée. Conclusion Le GECSSP adopte la recommandation en matière d’examen pelvien de dépistage, comme publiée par l’ACP en 2014.

  19. Segundo Catálogo Estelar del Hemisferio Sur con Astrolabio Fotoeléctrico PAII

    NASA Astrophysics Data System (ADS)

    Manrique, W. T.; Podestá, R. C.; Alonso, E.; Actis, E. V.; Pacheco, A. M.; Bustos, G.; Lizhi, L.; Zezhi, W.; Fanmiao, Z.; Hongqi, W.; Perdomo, R.

    Recordamos que entre el Observatorio Astronómico ``Félix Aguilar'', el Observatorio Astronómico de Beijing y el Observatorio Astronómico de La Plata, se ha convenido en desarrollar un Proyecto de Investigación conjunto, para la observación sistemática de estrellas en el Hemisferio Sur, con el objeto de la elaboración de un Catálogo Estelar Global utilizando un Astrolabio Fotoeléctrico PAII del Observatorio de Beijing, que ha sido usado con éxito en la República de China. En este trabajo se presenta el Segundo Catálogo Estelar del Hemisferio Sur, derivado de las observaciones realizadas con el PAII instalado en el OAFA, durante el períiodo Febrero de 1992 a Marzo de 1997. En este lapso se han observado mas de 400000 pasajes estelares, obteniéndose las correcciones Δ α y Δ δ de 5241 estrellas del FK4, FK5, FK5 Ext., SRS, CAMC y GC. Las precisiones medias son del orden de ± 3,2 ms en ascensión recta y ±0."057 en declinación. Rango de magnitudes : 2,0 a 11,5 Rango de declinaciones : -3o a -60o Epoca Media : 1994.9 Se analizan los residuos en función de la magnitud y tipo espectral, correcciones de grupo y frecuencia de distribución Δ α y Δ δ.

  20. Modern carbonate sediments and environments of the LaPaz region, Baja California Sur, Mexico

    SciTech Connect

    Halfar, J.; Ingle, J.C. Jr.; Cruz-Orozco, R.; Godinez-Orta, L.

    1996-12-31

    The Gulf of California represents one of the most productive and unique marginal seas in the world. The mouth of the Gulf captures warm equatorial water while annual wind patterns assure major upwelling of nutrient-rich water leading to a rich marine biota. These conditions have created a wide array of tropical through warm temperate carbonate environments. The most unusual of these environments is located in the La Paz region of Baja California Sur where tropical-subtropical water temperatures and low rainfall have allowed growth of corals, calcareous red algae, and other shelled invertebrates to form a carbonate bank environment. Sampling and mapping transacts in shallow bays north of La Paz and on the adjacent Espiritu Santo island have revealed a full spectrum of subenvironments including mangrove bordered, terrigenous mud dominated coastal zones, which grade into carbonate tidal flats. In addition, single coral heads as well as incipient reef structures constructed by Porites and Pocillopora coral are present in deeper water areas. Coralline red algae, which are increasingly utilized for paleoenvironmental reconstructions, grow in high abundance on coral debris and in soft sediments and turn out to be main contributors to the La Paz carbonates. Analysis of siliciclastic admixtures, grain size and organic carbon content allow a classification of distinct environments. These data are supplemented by an evaluation of benthic foraminiferal zonations and the varying abundance of biogenic constituents. This Baja California Sur carbonate environment holds special relevance for the interpretation of analogous Neogene and Paleogene paleoenvironments marking major paleoclimatic and paleoceanographic events along the Pacific Coast of North America.

  1. Modern carbonate sediments and environments of the LaPaz region, Baja California Sur, Mexico

    SciTech Connect

    Halfar, J.; Ingle, J.C. Jr. ); Cruz-Orozco, R. ); Godinez-Orta, L. )

    1996-01-01

    The Gulf of California represents one of the most productive and unique marginal seas in the world. The mouth of the Gulf captures warm equatorial water while annual wind patterns assure major upwelling of nutrient-rich water leading to a rich marine biota. These conditions have created a wide array of tropical through warm temperate carbonate environments. The most unusual of these environments is located in the La Paz region of Baja California Sur where tropical-subtropical water temperatures and low rainfall have allowed growth of corals, calcareous red algae, and other shelled invertebrates to form a carbonate bank environment. Sampling and mapping transacts in shallow bays north of La Paz and on the adjacent Espiritu Santo island have revealed a full spectrum of subenvironments including mangrove bordered, terrigenous mud dominated coastal zones, which grade into carbonate tidal flats. In addition, single coral heads as well as incipient reef structures constructed by Porites and Pocillopora coral are present in deeper water areas. Coralline red algae, which are increasingly utilized for paleoenvironmental reconstructions, grow in high abundance on coral debris and in soft sediments and turn out to be main contributors to the La Paz carbonates. Analysis of siliciclastic admixtures, grain size and organic carbon content allow a classification of distinct environments. These data are supplemented by an evaluation of benthic foraminiferal zonations and the varying abundance of biogenic constituents. This Baja California Sur carbonate environment holds special relevance for the interpretation of analogous Neogene and Paleogene paleoenvironments marking major paleoclimatic and paleoceanographic events along the Pacific Coast of North America.

  2. Etude Bacteriologique sur 30 Mois dans un Service de Brulés

    PubMed Central

    Chaibdraa, A.; Bentakouk, M.C.

    2008-01-01

    Summary Le pronostic des brûlures est souvent tributaire de complications infectieuses. Les objectifs de cette étude préliminaire rétrospective sont une évaluation de la flore microbienne et ses fluctuations selon la durée d'hospitalisation chez les patients du Centre des brûlés adultes de Annaba (Algérie). Ce travail porte sur 633 prélèvements microbiologiques positifs obtenus entre juin 2003 (inauguration du service) et décembre 2005. Selon le site de prélèvement la répartition est: cutané (78%), hémoculture (9%), prélèvement trachéo-bronchique (4%), uroculture (3%), sonde urinaire (3%), cathéter(3%). Les germes isolés sont: les staphylocoques (58%), les Pseudomonas (20%), le Candida albicans (5%), l'Acinetobacter (3%) et les autres germes (14%). Parmi les staphylocoques et les Pseudomonas recensés, respectivement 19% et 11% sont isolés la première semaine, contre 43% et 52% au-delà de 21 jours. Ces résultats confrontés aux données de la littérature confirment la prédominance du staphylocoque et du Pseudomonas. Le risque de contamination à partir des techniques invasives de réanimation est commun à toutes les équipes. La prolifération bactérienne est en relation avec la durée d'hospitalisation. Ces constatations doivent nous inciter à tirer bénéfice de l'expérience des autres services, en particulier sur les moyens, accessibles, de prévention de l'infection nosocomiale. PMID:21991102

  3. CGRO Observations

    NASA Technical Reports Server (NTRS)

    Kaaret, Philip

    1997-01-01

    This final report presents an investigation of the CGRO (Compton Gamma Ray Observatory) observations. The investigation includes: Diffuse Gamma-Ray Emission at High Latitudes; and Echoes in X-Ray Novae; A Localized Excess of Gamma-Radiation; Transient Hard X-Ray Emission from Globular Clusters; and A Search for Be/X-Ray Binaries in Hard X-Rays; Hard X-Ray Emission from X-Ray Bursters; X-Ray Transients in Star-Forming Regions; Gamma-ray Emission from Globular Clusters; Shock High Energy Emission from Be-Star/Pulsar System PSR 1259-63m; Gamma-Ray Spectroscopy of Nearby OB Associations; Long Term Hard X-Ray Monitoring of X-Ray Busters; and Periodic Hard X-Ray Emission from GRO J1849-03.

  4. ASCA Observations

    NASA Technical Reports Server (NTRS)

    Helfand, David J.

    1998-01-01

    This recently expired grant has supported the work of the PI, his students, and his collaborators on a variety of ASCA projects over the past four years. Annual reports have summarized much of the work accomplished; here we provide a brief review of the work resulting from this effort, and a summary of the personnel who have benefited from the grant's support. Starburst Galaxies with Extreme X-ray Luminosities This project began as a careful examination of the claims of Boller et al. (1992) that there were dozens of "normal" galaxies in the ROSAT All-Sky Survey that had X-ray luminosities in excess of 1042 erg sec, higher than that seen in the hundreds of non-AGN galaxies observed with Einstein. If true, this suggested that X-ray emission associated with star formation activity might have a significant contribution to make to the still unexplained cosmic X-ray background (XRB). Since some of our earlier work with the Einstein Observatory Deep Surveys had suggested a similar possibility and several sets of authors over the years had modelled the starburst XRB contribution, these claims were worth pursuing. Our work expanded the examination beyond the RASS to include earlier claims of high-luminosity galaxies powered by starburst emission (selected in this case on the basis of the far-IR luminosities). The result of extensive followup observations under several programs using ROSAT, ASCA, and ground-based facilities was to show that nearly all of these objects in fact have hidden AGN at their cores, and that their luminosities are not in any way extraordinary.

  5. Observational exobiology

    NASA Technical Reports Server (NTRS)

    Tarter, J.

    1986-01-01

    The Earth's atmosphere absorbs partially or completely many ultraviolet, infrared and submillimeter wavelengths. Atmospheric seeing distorts small images, imposing a limit on the achievable angular resolution at optical and infrared wavelengths that is much poorer than the intrinsic capability of telescope optics. The atomic and molecular species of the atmosphere confuse or prevent the spectral studies of similar compounds outside of the terrestrial environment. Telescopes placed in orbit above the atmosphere avoid these problems and enjoy a unique view of the universe. There are many complex questions pertaining to the origin and evolution of the biogenic elements and compounds and the existence of terrestrial types of planets elsewhere that can be only tackled from orbiting facilities. The detailed nature of the spacecraft, platforms and instrumentation most likely to be launched by the United States and Europe in the near future in an attempt to determine what observational programs would be tractable and which areas of interest to exobiology required hardware capabilities beyond those currently envisioned are considered.

  6. Carbonate chemistry and air-sea CO2 flux at a fixed point in a NW Mediterranean Bay, Villefranche-sur-Mer, France

    NASA Astrophysics Data System (ADS)

    De Carlo, E. H.; Mousseau, L.; Passafiume, O.; Drupp, P. S.; Gattuso, J.

    2011-12-01

    The purpose of the Service d'Observation de la Rade de Villefranche-sur-Mer (SO-RADE) is to study the temporal variability of hydrological conditions as well as the abundance and composition of holo- and meroplankton at a fixed station in the bay of Villefranche-sur-Mer, North West Mediterranean. The weekly data collected at this site, designated as "Point B (43° 41.10'N - 7° 18.94'E), since 1957 are recognized as a long-term time series describing the evolution of the hydrological conditions in a coastal environment. Since 2007, historical measurements of hydrological and biological conditions have been complemented by measurements of the CO2-carbonate system parameters. In this contribution we present CO2-carbonate system parameters and ancillary data for the period 2007-2010. The data are evaluated in the context of the physical and biogeochemical processes that contribute to the fluxes of CO2 between the ocean and atmosphere. Seasonal cycles of seawater pCO2 are controlled principally by variations in temperature, showing maxima in the summer and minima during the winters. Normalization of pCO2 to the mean seawater temperature (18oC) results in an apparent reversal of the seasonal cycle with maxima observed in the winters and minima in the summers, consistent with a control of pCO2 by primary productivity. Calculations of "instantaneous fluxes" of CO2 between the ocean and atmosphere show this area to be primarily a weak source of CO2 to the atmosphere during the summer and a weak sink during the winter and near neutral overall (range: -0.3 to +0.3 mmol CO2 m-2 h-1, average: 0.02 mmol CO2 m-2 h-1). We will also provide projections of errors incurred from the estimation of annualized fluxes of CO2 based on weekly measurements relative to daily and high-frequency (3 h) data such as those obtained at the Hawaii Kilo Nalu coastal time series station, which shows similar behavior to the Point B location despite significant differences in climate and hydrological

  7. Evaluation d'impact sur la santé et évaluation d'impact sur l'équité en santé : éventail de pratiques et questions de recherche.

    PubMed

    Villeval, Mélanie; Bidault, Elsa; Lang, Thierry

    2016-09-01

    L'Evaluation d'Impact sur la Santé (EIS) se développe au niveau international et est encore au stade émergent en France. Elle vise à évaluer les effets positifs et négatifs potentiels d'un projet, d'un programme ou d'une politique sur la santé. L'objectif est de produire des recommandations en direction des décideurs, afin d'en maximiser les effets positifs et d'en diminuer les effets négatifs. L'EIS est un moyen particulièrement intéressant d'action sur les déterminants de la santé au-delà des comportements individuels et du système de santé. Les politiques de logement, de transport, de solidarité, économiques, etc. ont, en effet, des impacts souvent non prévus sur la santé. Au-delà des effets sur la santé, l'EIS doit aussi permettre d'apprécier la distribution de ces effets dans la population.Si la préoccupation pour l'équité en santé est centrale dans l'EIS, elle reste cependant difficilement traduite en pratique. Face à cette difficulté, des démarches d'évaluation d'impact ont été développées pour renforcer la prise en compte de l'équité à chaque étape de l'EIS ou « Equity Focused Health Impact Assessment », ou prendre en compte les impacts sur les inégalités de santé de façon spécifique. Ainsi, l'Evaluation de l'Impact sur l'Equité en Santé (EIES) semble, par exemple, particulièrement intéressante pour évaluer l'impact sur les inégalités de projets dans le champ sanitaire.L'EIS et l'EIES posent de nombreuses questions de recherche, notamment autour de la réunion, dans une même démarche, du politique, du citoyen et de l'expert. La participation des populations vulnérables potentiellement affectées par la politique évaluée est une valeur centrale de l'EIS, mais pose des questions d'acceptabilité sociale. La collaboration avec les décideurs politiques est également un enjeu majeur. Les difficultés méthodologiques, notamment de quantification des impacts, peuvent constituer des freins à la promotion

  8. Evaluation d'impact sur la santé et évaluation d'impact sur l'équité en santé : éventail de pratiques et questions de recherche.

    PubMed

    Villeval, Mélanie; Bidault, Elsa; Lang, Thierry

    2016-09-01

    L'Evaluation d'Impact sur la Santé (EIS) se développe au niveau international et est encore au stade émergent en France. Elle vise à évaluer les effets positifs et négatifs potentiels d'un projet, d'un programme ou d'une politique sur la santé. L'objectif est de produire des recommandations en direction des décideurs, afin d'en maximiser les effets positifs et d'en diminuer les effets négatifs. L'EIS est un moyen particulièrement intéressant d'action sur les déterminants de la santé au-delà des comportements individuels et du système de santé. Les politiques de logement, de transport, de solidarité, économiques, etc. ont, en effet, des impacts souvent non prévus sur la santé. Au-delà des effets sur la santé, l'EIS doit aussi permettre d'apprécier la distribution de ces effets dans la population.Si la préoccupation pour l'équité en santé est centrale dans l'EIS, elle reste cependant difficilement traduite en pratique. Face à cette difficulté, des démarches d'évaluation d'impact ont été développées pour renforcer la prise en compte de l'équité à chaque étape de l'EIS ou « Equity Focused Health Impact Assessment », ou prendre en compte les impacts sur les inégalités de santé de façon spécifique. Ainsi, l'Evaluation de l'Impact sur l'Equité en Santé (EIES) semble, par exemple, particulièrement intéressante pour évaluer l'impact sur les inégalités de projets dans le champ sanitaire.L'EIS et l'EIES posent de nombreuses questions de recherche, notamment autour de la réunion, dans une même démarche, du politique, du citoyen et de l'expert. La participation des populations vulnérables potentiellement affectées par la politique évaluée est une valeur centrale de l'EIS, mais pose des questions d'acceptabilité sociale. La collaboration avec les décideurs politiques est également un enjeu majeur. Les difficultés méthodologiques, notamment de quantification des impacts, peuvent constituer des freins à la promotion

  9. Thermal-maturity trends within Franciscan rocks near Big Sur, California: Implications for offset along the San Gregorio San Simeon Hosgri fault zone

    NASA Astrophysics Data System (ADS)

    Underwood, Michael B.; Laughland, Matthew M.; Shelton, Kevin L.; Sedlock, Richard L.

    1995-09-01

    Conventional neotectonic interpretations place the Lucia and Point Sur subterranes of the Franciscan subduction complex on opposite sides of the San Gregorio San Simeon Hosgri dextral fault system and connect that system through the Sur fault zone. Our reconstructed paleotemperature contours, however, are not offset across the San Simeon segment, so differential displacement between the subterranes after peak heating appears to have been negligible. One explanation is that dextral slip on the faults has totaled only 5 10 km. A second possibility is that a discrete Hosgri San Simeon segment extends offshore of the amalgamated Point Sur and Lucia subterranes and that an en echelon stepover transfers dextral slip eastward to the San Gregorio Palo Colorado segment. In either case, the Sur fault zone appears to play a relatively insignificant role in the late Cenozoic tectonic evolution of central California.

  10. First record of a louse fly, Stilbometopa impressa (Bigot), and new host for Microlynchia pusilla (Speiser) (Hippoboscidae) from the Cape Region, Baja California Sur, México.

    PubMed

    Llinas, J; Jiménez, M L

    1996-04-01

    Nine of thirty California quail (Callipepla californica achrustera) captured in autumn of 1992, 17 km west of La Paz, Baja California Sur, México, were parasitized by louse flies. We identified eight Microlynchia pusilla and three Stilbometopa impressa from 30 quails in the ratio of 2.75:1. These are the first records of S. impressa for Cape Region and the first time either fly has been reported from the California quail in Baja California Sur. PMID:8722274

  11. Croissance epitaxiale de GaAs sur substrats de Ge par epitaxie par faisceaux chimiques

    NASA Astrophysics Data System (ADS)

    Belanger, Simon

    La situation energetique et les enjeux environnementaux auxquels la societe est confrontee entrainent un interet grandissant pour la production d'electricite a partir de l'energie solaire. Parmi les technologies actuellement disponibles, la filiere du photovoltaique a concentrateur solaire (CPV pour concentrator photovoltaics) possede un rendement superieur et mi potentiel interessant a condition que ses couts de production soient competitifs. La methode d'epitaxie par faisceaux chimiques (CBE pour chemical beam epitaxy) possede plusieurs caracteristiques qui la rendent interessante pour la production a grande echelle de cellules photovoltaiques a jonctions multiples a base de semi-conducteurs III-V. Ce type de cellule possede la meilleure efficacite atteinte a ce jour et est utilise sur les satellites et les systemes photovoltaiques a concentrateur solaire (CPV) les plus efficaces. Une des principales forces de la technique CBE se trouve dans son potentiel d'efficacite d'utilisation des materiaux source qui est superieur a celui de la technique d'epitaxie qui est couramment utilisee pour la production a grande echelle de ces cellules. Ce memoire de maitrise presente les travaux effectues dans le but d'evaluer le potentiel de la technique CBE pour realiser la croissance de couches de GaAs sur des substrats de Ge. Cette croissance constitue la premiere etape de fabrication de nombreux modeles de cellules solaires a haute performance decrites plus haut. La realisation de ce projet a necessite le developpement d'un procede de preparation de surface pour les substrats de germanium, la realisation de nombreuses sceances de croissance epitaxiale et la caracterisation des materiaux obtenus par microscopie optique, microscopie a force atomique (AFM), diffraction des rayons-X a haute resolution (HRXRD), microscopie electronique a transmission (TEM), photoluminescence a basse temperature (LTPL) et spectrometrie de masse des ions secondaires (SIMS). Les experiences ont permis

  12. Lignes directrices canadiennes sur la rhinosinusite bactérienne aiguë

    PubMed Central

    Kaplan, Alan

    2014-01-01

    Résumé Objectif Faire un résumé clinique des lignes directrices canadiennes sur la rhinosinusite bactérienne aiguë (RSBA) qui présente des éléments d’intérêt pour les médecins de famille. Source des données Les auteurs des lignes directrices ont effectué une recherche documentaire systématique et ont rédigé des recommandations. Une cote a été donnée à la fois en fonction de la fiabilité des données probantes et de la solidité des recommandations. On a sollicité les commentaires d’experts en la matière venant de l’extérieur, ainsi que l’aval de sociétés médicales canadiennes (Association pour la microbiologie médicale et l’infectiologie Canada, Société canadienne d’allergie et d’immunologie clinique, Société canadienne d’otorhinolaryngologie et de chirurgie cervicofaciale, Association canadienne des médecins d’urgence et Regroupement canadien des médecins de famille en santé respiratoire). Message principal Le diagnostic de la RSBA repose sur la présence de symptômes particuliers et leur durée; l’imagerie ou une culture n’est pas nécessaire dans les cas peu compliqués. Le traitement dépend de la gravité des symptômes, notamment avec des corticostéroïdes intranasaux (CSIN) recommandés comme monothérapie pour les cas de légers à modérés, quoique leurs bienfaits soient modestes. Le recours à des CSIN accompagnés d’antibiotiques est réservé aux patients qui ne répondent pas aux CSIN après 72 heures et comme traitement initial des patients dont les symptômes sont graves. Le choix de l’antibiotique doit tenir compte du pathogène soupçonné, du risque de résistance, des problèmes concomitants et des tendances locales de la résistance aux antimicrobiens. Des thérapies d’appoint comme l’irrigation nasale avec une solution saline sont recommandées. En présence de cas réfractaires au traitement, d’épisodes récurrents et de signes de complications, on devrait demander une

  13. Allergie respiratoire et “sunko”: une association rare, à propos d'une observation

    PubMed Central

    Ngombe, Léon Kabamba; Kangulu, Ignace Bwana; Nzaji, Michel Kabamba

    2014-01-01

    Il est rapporté dans ce texte un cas d'allergie respiratoire ayant fait probablement suite à une consommation d'un tabac sans fumé couramment utilisé en République Démocratique du Congo, le « Sunko ». Une rhinite et un asthme allergiques sont les cas. Cette observation permet d'attirer l'attention du monde scientifique à mettre sur pieds des études concernant la composition et les effets du Sunko pour appréhender cette association, puis d'informer l'opinion sur les dangers que courent les consommateurs de ce type de tabac et de faire la revue de la littérature. PMID:25426218

  14. Structural and functional insights into the stationary-phase survival protein SurE, an important virulence factor of Brucella abortus.

    PubMed

    Tarique, K F; Abdul Rehman, S A; Devi, S; Tomar, Priya; Gourinath, S

    2016-05-01

    The stationary-phase survival protein SurE from Brucella abortus (BaSurE) is a metal-dependent phosphatase that is essential for the survival of this bacterium in the stationary phase of its life cycle. Here, BaSurE has been biochemically characterized and its crystal structure has been determined to a resolution of 1.9 Å. BaSurE was found to be a robust enzyme, showing activity over wide ranges of temperature and pH and with various phosphoester substrates. The active biomolecule is a tetramer and each monomer was found to consist of two domains: an N-terminal domain, which forms an approximate α + β fold, and a C-terminal domain that belongs to the α/β class. The active site lies at the junction of these two domains and was identified by the presence of conserved negatively charged residues and a bound Mg(2+) ion. Comparisons of BaSurE with its homologues have revealed both common features and differences in this class of enzymes. The number and arrangement of some of the equivalent secondary structures, which are seen to differ between BaSurE and its homologues, are responsible for a difference in the size of the active-site area and the overall oligomeric state of this enzyme in other organisms. As it is absent in mammals, it has the potential to be a drug target.

  15. Structural and functional insights into the stationary-phase survival protein SurE, an important virulence factor of Brucella abortus.

    PubMed

    Tarique, K F; Abdul Rehman, S A; Devi, S; Tomar, Priya; Gourinath, S

    2016-05-01

    The stationary-phase survival protein SurE from Brucella abortus (BaSurE) is a metal-dependent phosphatase that is essential for the survival of this bacterium in the stationary phase of its life cycle. Here, BaSurE has been biochemically characterized and its crystal structure has been determined to a resolution of 1.9 Å. BaSurE was found to be a robust enzyme, showing activity over wide ranges of temperature and pH and with various phosphoester substrates. The active biomolecule is a tetramer and each monomer was found to consist of two domains: an N-terminal domain, which forms an approximate α + β fold, and a C-terminal domain that belongs to the α/β class. The active site lies at the junction of these two domains and was identified by the presence of conserved negatively charged residues and a bound Mg(2+) ion. Comparisons of BaSurE with its homologues have revealed both common features and differences in this class of enzymes. The number and arrangement of some of the equivalent secondary structures, which are seen to differ between BaSurE and its homologues, are responsible for a difference in the size of the active-site area and the overall oligomeric state of this enzyme in other organisms. As it is absent in mammals, it has the potential to be a drug target. PMID:27139831

  16. La violence sur les réseaux canadiens de télévision

    PubMed Central

    Paquette, Guy

    2003-01-01

    La question des effets de la violence à la télévision occupe une place très importante dans l’opinion publique depuis les vingt dernières années, et des centaines d’études y ont été consacrées. Plusieurs chercheurs concluent à une influence négative de cette violence sur le comportement. Le public, les diffuseurs et les autorités politiques ont tous endossé l’idée de réduire la quantité totale de violence présentée au petit écran – en particulier dans les émissions accessibles aux enfants. Nous avons analysé un millier d’émissions de fiction présentées entre 1993 et 2001 sur les principaux réseaux généralistes de télévision au Canada : TVA et TQS ainsi que CTV et Global pour les réseaux privés français et anglais, ainsi que Radio-Canada français et anglais pour les réseaux publics. La méthodologie utilisée est l’analyse de contenu classique, où l’acte de violence constitue l’unité d’analyse. Les données recueillies démontrent que la quantité de violence a augmenté régulièrement depuis 1993, malgré la volonté affirmée des télédiffuseurs de présenter une programmation moins violente. C’est le cas du nombre brut d’actes et du nombre d’actes à l’heure, qui est lui aussi en forte croissance. Les réseaux privés véhiculent trois fois plus de violence que les réseaux publics. On constate également qu’une très forte proportion d’actes de violence figure dans des émissions qui commencent avant 21 h, et que de nombreux enfants y sont probablement exposés. Nous signalons finalement la place de plus en plus importante occupée par la violence psychologique. PMID:20020031

  17. Mise à jour sur l’utilisation clinique de la buprénorphine

    PubMed Central

    Ducharme, Simon; Fraser, Ronald; Gill, Kathryn

    2012-01-01

    Résumé Objectif Examiner les données scientifiques actuelles sur la buprénorphine-naloxone pour le traitement des troubles liés aux opioïdes, en insistant sur le contexte des soins primaires. Qualité des données On a fait une recension dans MEDLINE et la base de données Cochrane des synthèses critiques. Les données probantes sont surtout de niveau I. Message principal La buprénorphine est un agoniste partiel des récepteurs μ des opioïdes et un antagoniste des récepteurs κ des opioïdes ayant une longue demi-vie et un potentiel moins grand que la méthadone d’entraîner un usage abusif. Pour une désintoxication, la buprénorphine est au moins équivalente à la méthadone et supérieure à la clonidine. Comme thérapie de substitution, la buprénorphine est clairement supérieure au placebo. La méthadone comporte de légers avantages en ce qui a trait à la rétention en thérapie, mais une approche par étape en utilisant initialement la buprénorphine-naloxone est aussi efficace. Il est possible, sécuritaire et efficace de recourir à la buprénorphine en milieu de soins primaires. On peut obtenir l’autorisation de prescrire de la buprénorphine après avoir suivi une formation en ligne. Conclusion La buprénorphine est un agent sécuritaire et efficace pour la désintoxication en cas de dépendance aux opioïdes. Elle peut servir d’agent de première intention dans les programmes de thérapie de substitution, en raison de son potentiel plus faible d’usage abusif en comparaison d’autres opioïdes. Son efficacité en milieux de soins primaires en fait un outil thérapeutique utile pour les médecins de famille.

  18. Enquete sur les aspects toxicologiques de la phytotherapie utilisee par un herboriste à Fes, Maroc

    PubMed Central

    Zeggwagh, Ali Amine; Lahlou, Younes; Bousliman, Yassir

    2013-01-01

    Introduction Dans le but d'étudier l'aspect toxicologique des plantes médicinales utilisées en médecine traditionnelle, une étude ethnobotanique a été réalisée à la ville de Fès au centre du Maroc. Méthodes Ont été inclus dans l'étude tous les patients ayant bénéficié d'une prescription par l'herboriste de plantes à visée thérapeutique. La discussion de nos résultats s'est faite sur la base d'une revue de la littérature avec identification des principales plantes toxiques utilisées en phytothérapie au Maroc. L'approche bibliographique a permis de compléter les informations. Résultats L'âge moyen des patients traités par des plantes (38 femmes, 32 hommes) était de 35 ± 18 ans. L'enquête ethnobotanique à révélé que la majorité des plantes médicinales étaient utilisées contre les affections urinaires (21%), suivi des maladies de l'appareil digestif (19.6%) et des maladies rhumatologiques (18.2%). Le nombre de plantes prescrits par l'herboriste a été de 53 dont 5 sont potentiellement toxiques. L'identification taxonomique des plantes prescrites a recensé 30 familles dont les plus représentées sont les Lamiaceae (23.33%), les Apiaceae (13,33%) et les Asteraceae (10%). La prescription des plantes considérées comme toxiques a concerné 7,1% des consultants traités par les plantes médicinales. Aucune complication inhérente aux plantes prescrites n'a été déplorée. Conclusion Malgré les résultats encourageants de notre enquête sur le compte de la phytothérapie, la pratique de la phytothérapie est laissée à la vulgarisation et à l'oubli scientifique, législatif et universitaire. PMID:23734270

  19. Bio-optical profile data report coastal transition zone program, R/V Point Sur, June 15-28, 1987

    NASA Technical Reports Server (NTRS)

    Davis, Curtiss O.; Rhea, W. Joseph

    1990-01-01

    Twenty vertical profiles of the bio-optical properties of the ocean were made during a research cruise on the R/V Point Sur, June 15 to 28, 1987, as part of the Coastal Transition Zone Program off Point Arena, California. Extracted chlorophyll values were also measured at some stations to provide calibration data for the in situ fluorometer. This summary provides investigators with an overview of the data collected. The entire data set is available in digital form.

  20. Map showing coastal cliff retreat rates along the Big Sur coast, Monterey and San Luis Obispo Counties, California

    USGS Publications Warehouse

    Hapke, Cheryl J.; Green, Krystal R.

    2004-01-01

    The average coastal cliff retreat rate along the Big Sur coast is 18 ? 6 cm/yr as measured over a 52-year time period. The erosion reference features measured as the cliff edge include the well-defined cliff edges common to marine terraces, slight breaks in the slope defining the upper edge of the active lower slope, and the road grade. Cliff erosion and retreat are focused in isolated erosion hotspots that account for most of the calculated average retreat.

  1. Décohésion d'interfaces dans des couches de NiO sur du nickel industriel de pureté variable

    NASA Astrophysics Data System (ADS)

    Chirat, B.; Haut, C.; Huntz, A. M.; Andrieux, M.; Feltz, B.

    2003-03-01

    L'oxydation sous air de deux nickel de pureté industrielle mais de provenance différente a été étudiée, principalement à 800^{circ}C. Outre la cinétique d'oxydation et la morphologie des couches de NiO, l'étude a été focalisée sur les caractéristiques mécaniques des couches de NiO. Celles-ci ont été caractérisées à la température ambiante, essentiellement par flexion trois points sous MEB. Si la cinétique d'oxydation des deux métaux industriels est voisine et associée à des morphologies de couches assez complexes mais similaires, il n'en est pas de même pour la majorité des caractéristiques mécaniques. Ainsi, même en prenant en compte l'évolution des caractéristiques mécaniques du nickel avec le temps de traitement, on observe des différences dans les valeurs de KIC des couches de NiO selon la nature du substrat et l'épaisseur de la couche d'oxyde, c'est-à-dire avec la durée de l'oxydation. Enfin et surtout, le comportement vis-à-vis de la décohésion est très différent : il est pratiquement impossible d'écailler les couches de NiO formées sur l'un des nickel, tandis que la décohésion est obtenue avec une relative facilité dans le cas de l'autre nickel. Mais, cette décohésion n'a pas lieu à l'interface métal-oxyde, mais à l'interface oxyde-oxyde, en raison de la formation de deux couches de NiO, l'une interne, l'autre externe.

  2. Une étude rétrospective sur le cancer de l'ovaire avec un recul médian de 42 mois

    PubMed Central

    Raherinantenaina, Fanomezantsoa; Rakotomena, Solonirina Davidà; Hasiniatsy, Nomeharisoa Rodrigue Emile; Rakototiana, Felantsoa Auberlin; Rafaramino, Florine; Ratsimba, Hery Nirina Rakoto

    2015-01-01

    Le cancer de l'ovaire est relativement fréquent mais grave et de mauvais pronostic. Le but de cette étude était de mettre en évidence les aspects épidémiologique, diagnostique, thérapeutique et évolutif de cette pathologie maligne prise en charge dans un pays en développement. Il s'agit d'une étude rétrospective et descriptive de 10 ans (2000- 2009) effectuée dans un CHU de chirurgie générale et d'Oncologie sur 62 patientes ayant développé un cancer de l'ovaire et opérées à visée curative. L’âge moyen des patientes était de 43 ans dont 53,23% avaient plus de 45 ans. Le dosage sanguin du CA-125 était positif chez 10 patientes sur 12. Les tumeurs étaient découvertes à l’échographie dans 87,10% des cas et à la laparotomie dans 12,90%. L'hystérectomie totale avec annexectomie bilatérale était l'intervention la plus pratiquée (64,52%). Les suites opératoires précoces étaient simples. Dix patientes étaient opérées de second regard (16,13%) pour des récidives locorégionales. Les tumeurs épithéliales étaient le type histologique le plus fréquent (93,55%) dont 79% au stade avancé (Ic-IV) et 21% au stade précoce (Ia-Ib). La chimiothérapie adjuvante était administrée chez 22,60% des patientes. Avec un recul médian de 42 mois, 29 patientes étaient perdues de vue. L’évolution était favorable dans 27,42% et dans 25,81% les décès se sont survenus en postopératoire tardif. Le cancer de l'ovaire n’était pas fréquent mais grave compte tenu des stades avancés et du taux élevé des décès postopératoires tardifs qui étaient largement observés chez les patientes privées d'une chimiothérapie adéquate. PMID:26113942

  3. Transport de particules massives dans un fluide turbulent: Application a l'erosion due au sable sur les parois d'une turbine hydraulique

    NASA Astrophysics Data System (ADS)

    Bergeron, Stephen

    'aide de ce logiciel correspondent très bien avec celles observées sur le terrain. Une parallélisation à gros grain (``coarse grain parallelism'') est incluse intrinsèquement dans l'algorithme résultant. Une version du logiciel utilisant le passage de message sur un réseau hétérogène de stations de travail a été mise au point et est utilisée dans le cas de géométries de taille intermédiaire. Cette implémentation permet ainsi de rentabiliser l'utilisation des stations de travail déjà disponibles plutôt que de recourir à un serveur plus coûteux, ce qui est un avantage dans un contexte de recherche industrielle.

  4. Abdomen aigu sur une torsion de rate ectopique: à propos d'un cas

    PubMed Central

    Khalid, Elhattabi; Fatimazahra, Bensardi; Rachid, Lefriyekh; Abdelaziz, Fadil; Mohamed, Lahkim; Nadia, Benissa; Driss, Khaiz; Saad, Berrada; Najib, Zerouali Ouariti

    2012-01-01

    La rate ectopique est une entité rare dont l'incidence est mal connue. La torsion de son pédicule est une complication grave, qui doit bénéficier d'un diagnostic précoce; évitant ainsi la splénectomie surtout chez des patients jeunes. Nous rapportons le cas d'une patiente âgée de 39 ans; admise aux urgences dans un tableau d'abdomen aigu chirurgical, l'examen clinique, l’échographie et la tomodensitométrie abdominale ont contribué au diagnostic de torsion d'une rate ectopique en position hypogastrique, la splénectomie a été réalisée devant la découverte peropératoire de taches de nécrose sur la rate tordue. Le diagnostic de torsion d'une rate ectopique doit être suspecté devant l'association d'un abdomen aigu et la palpation d'une masse abdominale. L’échographie et la tomodensitométrie abdominale confirment le diagnostic. Le traitement est chirurgical; il consiste en une splénopexie qui est plus approprié. En présence de nécrose, la splénectomie doit être réalisée aussi bien par voie laparoscopique que par laparotomie. PMID:22655096

  5. The two Coissac's novels : l'Envol and Sur la Lune

    NASA Astrophysics Data System (ADS)

    Villain, Jacques

    2002-01-01

    Coissac wrote two novels with his friend Charles Rouch.: "L'Envol" in 1934 and "Sur la Lune" in 1935. In these books he describes the preparation of the lunar rocket weigthing 3000 tons and powered by solid propellants. This rocket is launched from a base built at the top of a peruvian volcano. The seven men crew (5 french and one american) is sent to the Moon in a 45 tons command module from which two lunar modules can be separated and can descent to the lunar surface. Coissac describes along the trajectory the means to guide and control the rocket. The exploration of the Moon is done with bicycles ans suits. The explorers meet strange animals and strange people living under ground like termites in perfect love and happiness. After having explored the two faces of the Moon, the lunar modules leave the Moon for a docking with the main vehicle waiting on a lunar orbit and the crew comes back to the Earth. The spacecraft lands in the Pacific Ocean. Except the direct flight from Earth to the Moon, the travel to the Moon proposed by Coissac is very similar to that of Apollo but more than thirty years earlier.

  6. The Reality of Neandertal Symbolic Behavior at the Grotte du Renne, Arcy-sur-Cure, France

    PubMed Central

    Caron, François; d'Errico, Francesco; Del Moral, Pierre; Santos, Frédéric; Zilhão, João

    2011-01-01

    Background The question of whether symbolically mediated behavior is exclusive to modern humans or shared with anatomically archaic populations such as the Neandertals is hotly debated. At the Grotte du Renne, Arcy-sur-Cure, France, the Châtelperronian levels contain Neandertal remains and large numbers of personal ornaments, decorated bone tools and colorants, but it has been suggested that this association reflects intrusion of the symbolic artifacts from the overlying Protoaurignacian and/or of the Neandertal remains from the underlying Mousterian. Methodology/Principal Findings We tested these hypotheses against the horizontal and vertical distributions of the various categories of diagnostic finds and statistically assessed the probability that the Châtelperronian levels are of mixed composition. Our results reject that the associations result from large or small scale, localized or generalized post-depositional displacement, and they imply that incomplete sample decontamination is the parsimonious explanation for the stratigraphic anomalies seen in the radiocarbon dating of the sequence. Conclusions/Significance The symbolic artifacts in the Châtelperronian of the Grotte du Renne are indeed Neandertal material culture. PMID:21738702

  7. Relevamiento total del hemisferio sur celeste en la frecuencia de 1420 MHz

    NASA Astrophysics Data System (ADS)

    Bava, J. A.; Colomb, F. R.; Hurrel, E.; Larrarte, J. J.; Sanz, A. J.; Testori, J. C.; Reich, P.; Reich, W.; Wielebinski, R.

    En el presente artículo se describe el relevamiento del cielo en el Hemisferio Sur Celeste en la frecuencia de 1420 MHz para declinaciones δ<= -19o realizado con la Antena II de 30 metros de diámetro del IAR. Este relevamiento posee igual sensibilidad (3xr.m.s=50 mK) que el realizado en el Hemisferio Norte con el radiotelescopio de 25 metros de Stockert de la Universidad de Bonn, operado por el Max-Planck Institute für Radioastronomie ( Reich W., 1982, A&ASS 48, 219; Reich P. and Reich W., 1986, A&ASS 63, 205). Con los datos obtenidos por ambos radiotelescopios se posee una base de datos de todo el cielo en esta frecuencia. En esta publicación presentamos los detalles del sistema receptor, técnicas de observación y reducción de datos, calibración y discusión de los errores en los resultados.

  8. Isostatic gravity map of the Point Sur 30 x 60 quadrangle and adjacent areas, California

    USGS Publications Warehouse

    Watt, J.T.; Morin, R.L.; Langenheim, V.E.

    2011-01-01

    This isostatic residual gravity map is part of a regional effort to investigate the tectonics and water resources of the central Coast Range. This map serves as a basis for modeling the shape of basins and for determining the location and geometry of faults in the area. Local spatial variations in the Earth's gravity field (after removing variations caused by instrument drift, earth-tides, latitude, elevation, terrain, and deep crustal structure), as expressed by the isostatic anomaly, reflect the distribution of densities in the mid- to upper crust, which in turn can be related to rock type. Steep gradients in the isostatic gravity field often indicate lithologic or structural boundaries. Gravity highs reflect the Mesozoic granitic and Franciscan Complex basement rocks that comprise both the northwest-trending Santa Lucia and Gabilan Ranges, whereas gravity lows in Salinas Valley and the offshore basins reflect the thick accumulations of low-density alluvial and marine sediment. Gravity lows also occur where there are thick deposits of low-density Monterey Formation in the hills southeast of Arroyo Seco (>2 km, Marion, 1986). Within the map area, isostatic residual gravity values range from approximately -60 mGal offshore in the northern part of the Sur basin to approximately 22 mGal in the Santa Lucia Range.

  9. Uranium-series ages of marine terraces, La Paz Peninsula, Baja California Sur, Mexico

    USGS Publications Warehouse

    Sirkin, L.; Szabo, B. J.; Padilla, G.A.; Pedrin, S.A.; Diaz, E.R.

    1990-01-01

    Uranium-series dating of coral samples from raised marine terrace deposits between 1.5 and 10 m above sea level in the La Paz Peninsula area, Baja California Sur, yielded ages between 123 ka and 138 ka that are in agreement with previously reported results. The stratigraphy and ages of marine units near the El Coyote Arroyo indicate the presence of two high stands of the sea during the last interglacial or oxygen isotope substage 5e at about 140 ka and 123 ka. Accepting 5 m for the sea level during the last interglacial transgression, we calculate average uplift rates for the marine terraces of about ???70 mm/ka and 40 mm/ka. These slow rates of uplift indicate a relative stability of the La Paz peninsula area for the past 140 000 years. In contrast, areas of Baja California affected by major faultf experienced higher rates of uplift. Rockwell et al. (1987) reported vertical uplift rates of 180 to 300 mm/ka at Punta Banda within the Aqua Blanea fault zone in northern Baja California. ?? 1990 Springer-Verlag.

  10. Geothermal Exploration Using Remote Sensing in the South of Baja California Sur, Mexico

    NASA Astrophysics Data System (ADS)

    Báncora, Cristina; Prol-Ledesma, Rosa María

    2008-05-01

    The area from Ciudad Constitución to Los Cabos in Baja California Sur was studied using a mosaic of four Landsat ETM+images. The main objective was to define favorable areas for utilization and exploitation of geothermal energy. The approach was to spectrally and spatially enhance the images to define characteristics related with geothermal activity, as are the presence of altered rock and main geological structures. The products of hydrothermal alteration are minerals that belong to two main groups: oxides and hydroxyls. Therefore, image processing is necessary to enhance oxides and hydroxyls spectral features and subdue the vegetation spectral characteristics. The band subtraction (4-3, 3-1, 5-7) gave the finest results due to the fact that it is a linear equation that does not cause loss of information when it is stretched. A color composite was done with these three layers and after a detailed visual analysis three areas were point out to be prospective to contain hydrothermal activity.

  11. Influence of Carbonate Crusts on Trophic Cascades in Big Sur Streams.

    NASA Astrophysics Data System (ADS)

    Rundio, D.; Lindley, S.

    2005-05-01

    Top-down effects of fish predation in streams are influenced by habitat conditions and traits of intermediate consumers. Along the Big Sur coast, seasonal carbonate crusts form in many streams, and appear to alter insect communities. We conducted a small-scale field experiment in two adjacent tributaries (crusted and crust-free) to determine the effects of predation by juvenile steelhead (Oncorhynchus mykiss) on invertebrates and algae in these different stream types. We hypothesized that a trophic cascade would be more likely in the crusted stream, which was dominated by an herbivore vulnerable to steelhead predation (Baetis), than in the crust-free stream, which was dominated by a less vulnerable herbivore (Agapetus). However, excluding steelhead from paving bricks had no effect on algae or Baetis in the crusted stream. Algal abundance was low, suggesting possible bottom-up control. In the crust-free stream, steelhead predation did not affect Agapetus, but nevertheless produced a trophic cascade by causing Baetis to increase by 85%, which in turn depressed algae by 25%. These results suggest that trophic interactions may differ between crust forming and non-crust forming streams, which we plan to test with additional sampling and experiments replicated across stream types.

  12. Modelisation de la diffusion sur les surfaces metalliques: De l'adatome aux processus de croissance

    NASA Astrophysics Data System (ADS)

    Boisvert, Ghyslain

    Cette these est consacree a l'etude des processus de diffusion en surface dans le but ultime de comprendre, et de modeliser, la croissance d'une couche mince. L'importance de bien mai triser la croissance est primordiale compte tenu de son role dans la miniaturisation des circuits electroniques. Nous etudions ici les surface des metaux nobles et de ceux de la fin de la serie de transition. Dans un premier temps, nous nous interessons a la diffusion d'un simple adatome sur une surface metallique. Nous avons, entre autres, mis en evidence l'apparition d'une correlation entre evenements successifs lorsque la temperature est comparable a la barriere de diffusion, i.e., la diffusion ne peut pas etre associee a une marche aleatoire. Nous proposons un modele phenomenologique simple qui reproduit bien les resultats des simulations. Ces calculs nous ont aussi permis de montrer que la diffusion obeit a la loi de Meyer-Neldel. Cette loi stipule que, pour un processus active, le prefacteur augmente exponentiellement avec la barriere. En plus, ce travail permet de clarifier l'origine physique de cette loi. En comparant les resultats dynamiques aux resultats statiques, on se rend compte que la barriere extraite des calculs dynamiques est essentiellement la meme que celle obtenue par une approche statique, beaucoup plus simple. On peut donc obtenir cette barriere a l'aide de methodes plus precises, i.e., ab initio, comme la theorie de la fonctionnelle de la densite, qui sont aussi malheureusement beaucoup plus lourdes. C'est ce que nous avons fait pour plusieurs systemes metalliques. Nos resultats avec cette derniere approche se comparent tres bien aux resultats experimentaux. Nous nous sommes attardes plus longuement a la surface (111) du platine. Cette surface regorge de particularites interessantes, comme la forme d'equilibre non-hexagonale des i lots et deux sites d'adsorption differents pour l'adatome. De plus, des calculs ab initio precedents n'ont pas reussi a confirmer la

  13. Stratigraphy of Pyroclastic Deposits of EL Aguajito Caldera, Baja California Sur, MÉXICO

    NASA Astrophysics Data System (ADS)

    Osorio Ocampo, L. S.; Macias, J. L.; García Sánchez, L.; Pola, A.; Saucedo, R.; Sánchez, J. M.; Avellán, D. R.; Cardona, S.; Reyes-Agustín, G.; Arce, J. L.

    2015-12-01

    El Aguajito caldera is located in the State of Baja California Sur, it comprises an area of 450 km2 and sits within the Santa Rosalía Basin which is controlled by NE-SW extensional structures and the NW-SE Cimarron Fault that transects the caldera structure. The oldest rocks are ~90 Ma granodiorites covered by an Oligocene-Miocene volcano-sedimentary sequence, the Miocene Santa Lucia Formation and La Esperanza basalt. Pliocene volcanism is represented by La Reforma caldera, El Aguajito caldera, and the Tres Vírgenes Volcanic complex. This study focuses on the cartography and stratigraphy of area in order to understand the evolution of the volcanic system. The stratigraphy from base to top consists of a series of shallow marine sediments (fossiliferous sandstones) covered by a thick sequence of ignimbrites and pyroclastic flows interbedded with volcaniclastic deposits (Gloria and El Infierno Formations). On top of these deposits is El Aguajito caldera, it consists of a 2 m thick pumice fallout followed by an ignimbrite with three transitional lithofacies: a ≤30-m thick light-pink pyroclastic flow enriched in pumice at the base that gradually becomes enrich in lithics towards the top with the occurrence of degasing pipes. On top rests a 15 m-thick light-purple ignimbrite slightly welded with fiammes and a sequence of pumiceous pyroclastic flows and fallouts. These deposits have been associate to the caldera formation with a collapse diameter of ~8 km marked by rhyolitic domes exposed along a ring collapse crowned the sequence as well as NW-SE aligned rhyolitic domes parallel to the seashore. This cartography allowed to present a preliminary new geological map with four stratigraphic units recognized so far, that were emplaced under subaerial conditions beginning with a Plinian column followed by the emplacement of El Aguajito ignimbrite with its subsequent caldera collapse and finally the extrusion of resurgent domes.

  14. Availability of safe drinking-water: the answer to cholera outbreak? Nabua, Camarines Sur, Philippines, 2012

    PubMed Central

    de los Reyes, Vikki Carr; Sucaldito, Ma Nemia; Tayag, Enrique

    2015-01-01

    Background In May 2012, there were increasing diarrhoea cases and deaths reported from Nabua, Camarines Sur to the Philippines event-based surveillance system. An investigation was conducted to identify risk factors and determine transmission dynamics. Methods A suspected case was defined as a resident of Nabua with at least three episodes of watery diarrhoea per day from 16 March to 22 June 2012. A confirmed case was defined as a suspected case positive for Vibrio cholerae. An environmental investigation was conducted and rectal swabs and water samples sent to the national reference laboratory for bacterial isolation. A 1:2 case-control study matching for age and sex was conducted. Data were analysed using Epi Info. Results There were 309 suspected cases with two deaths, and the most affected age group was children under five years (45%). Eight cases were positive for Vibrio cholerae Ogawa El Tor and one for Non-01. Water samples were positive for faecal coliforms and Aeromonas caviae. The case-control study showed that cases had a higher odds than controls of using unchlorinated water sources (odds ratio [OR] = 3.6; 95% confidence interval [CI]:1.6–8.5) and having toilets located within 20 m of a septic tank (OR = 2.7; 95% CI: 1.4–5.3). In multivariate analysis, the only significant factor was drinking from piped water (OR = 0.21; 95% CI: 0.09–0.49). Discussion In this cholera outbreak, drinking-water from unchlorinated wells was a significant risk factor. Future cholera control efforts should include not just improving water and sanitation systems but also intensified behaviour change campaigns. PMID:26668761

  15. L'effet des deformations plastiques severes sur les proprietes d'hydruration du magnesium

    NASA Astrophysics Data System (ADS)

    Lang, Julien

    Le travail de recherche effectue durant mon projet de maitrise en physique a l'Universite du Quebec a Trois-Rivieres dans les laboratoires de l'Institut de Recherche sur l'Hydrogene etait de comparer l'effet du laminage a froid de la poudre de MgH2 avec celui du broyage mecanique. Nous avons etudie cette nouvelle technique en utilisant un laminoir vertical concu specialement pour laminer de la poudre. Nous avons lamine la poudre de MgH2 5, 25, 50 et 100 fois. La comparaison de la morphologie de la poudre de MgH 2 telle que recu du manufacturier et broye mecaniquement pendant 30 minutes avec celle de la poudre laminee ete faite a l'aide d'un microscope electronique a balayage. Nous avons par la suite mesure les proprietes de sorption d'hydrogene grace un appareil PCT de type Sievert. Nous avons aussi determine la structure cristalline par diffraction de rayons X. A partir de ces resultats, nous avons constate que le nombre optimal de laminages est de cinq et a les caracteristiques d'absorption/desorption d'hydrogene similaires a un broyage mecanique de 30 minutes. Nous avons aussi utilise les courbes de cinetiques d'absorption et de desorption d'hydrogene pour calculer l'etape limitative dans les reactions de sorption des echantillons lamines. Comme cinq laminages se font en environ 10 secondes, on voit que le laminage a froid est une technique plus interessante industriellement que le broyage mecanique a cause de l'important gain en temps et en energie.

  16. Regulation of myometrial contraction by ATP-sensitive potassium (KATP) channel via activation of SUR2B and Kir 6.2 in mouse.

    PubMed

    Hong, Seung Hwa; Kyeong, Kyu-Sang; Kim, Chan Hyung; Kim, Young Chul; Choi, Woong; Yoo, Ra Young; Kim, Hun Sik; Park, Yeon Jin; Ji, Il Woon; Jeong, Eun-Hwan; Kim, Hak Soon; Xu, Wen-Xie; Lee, Sang Jin

    2016-08-01

    ATP-sensitive potassium (KATP) channels are well characterized in cardiac, pancreatic and many other muscle cells. In the present study, functional expression of the KATP channel was examined in non-pregnant murine longitudinal myometrium. Isometric contraction measurements and Western blot were used. KATP channel openers (KCOs), such as pinacidil, cromakalim, diazoxide and nicorandil, inhibited spontaneous myometrial contractions in a reversible and glibenclamide-sensitive manner. KCOs inhibited oxytocin (OXT)- and prostaglandin F2α (PGF2α)-induced phasic contractions in a glibenclamide-sensitive manner. SUR2B and Kir6.2 were detected by Western blot, whereas SUR1, SUR2A and Kir6.1 were not. These results show that pinacidl, cromakalim, diazoxide and nicorandil-sensitive KATP channels exist in murine myometrium, which are composed of SUR2B and Kir6.2. Based on the modulatory effects of the KATP channel on spontaneous contraction, OXT- and PGF2α-induced contractions, KATP channels seem to play an essential role in murine myometrial motility via activation of SUR2B and Kir6.2.

  17. Regulation of myometrial contraction by ATP-sensitive potassium (KATP) channel via activation of SUR2B and Kir 6.2 in mouse

    PubMed Central

    HONG, Seung Hwa; KYEONG, Kyu-Sang; KIM, Chan Hyung; KIM, Young Chul; CHOI, Woong; YOO, Ra Young; KIM, Hun Sik; PARK, Yeon Jin; JI, Il Woon; JEONG, Eun-Hwan; KIM, Hak Soon; XU, Wen-Xie; LEE, Sang Jin

    2016-01-01

    ATP-sensitive potassium (KATP) channels are well characterized in cardiac, pancreatic and many other muscle cells. In the present study, functional expression of the KATP channel was examined in non-pregnant murine longitudinal myometrium. Isometric contraction measurements and Western blot were used. KATP channel openers (KCOs), such as pinacidil, cromakalim, diazoxide and nicorandil, inhibited spontaneous myometrial contractions in a reversible and glibenclamide-sensitive manner. KCOs inhibited oxytocin (OXT)- and prostaglandin F2α (PGF2α)-induced phasic contractions in a glibenclamide-sensitive manner. SUR2B and Kir6.2 were detected by Western blot, whereas SUR1, SUR2A and Kir6.1 were not. These results show that pinacidl, cromakalim, diazoxide and nicorandil-sensitive KATP channels exist in murine myometrium, which are composed of SUR2B and Kir6.2. Based on the modulatory effects of the KATP channel on spontaneous contraction, OXT- and PGF2α-induced contractions, KATP channels seem to play an essential role in murine myometrial motility via activation of SUR2B and Kir6.2. PMID:27086859

  18. Regulation of myometrial contraction by ATP-sensitive potassium (KATP) channel via activation of SUR2B and Kir 6.2 in mouse.

    PubMed

    Hong, Seung Hwa; Kyeong, Kyu-Sang; Kim, Chan Hyung; Kim, Young Chul; Choi, Woong; Yoo, Ra Young; Kim, Hun Sik; Park, Yeon Jin; Ji, Il Woon; Jeong, Eun-Hwan; Kim, Hak Soon; Xu, Wen-Xie; Lee, Sang Jin

    2016-08-01

    ATP-sensitive potassium (KATP) channels are well characterized in cardiac, pancreatic and many other muscle cells. In the present study, functional expression of the KATP channel was examined in non-pregnant murine longitudinal myometrium. Isometric contraction measurements and Western blot were used. KATP channel openers (KCOs), such as pinacidil, cromakalim, diazoxide and nicorandil, inhibited spontaneous myometrial contractions in a reversible and glibenclamide-sensitive manner. KCOs inhibited oxytocin (OXT)- and prostaglandin F2α (PGF2α)-induced phasic contractions in a glibenclamide-sensitive manner. SUR2B and Kir6.2 were detected by Western blot, whereas SUR1, SUR2A and Kir6.1 were not. These results show that pinacidl, cromakalim, diazoxide and nicorandil-sensitive KATP channels exist in murine myometrium, which are composed of SUR2B and Kir6.2. Based on the modulatory effects of the KATP channel on spontaneous contraction, OXT- and PGF2α-induced contractions, KATP channels seem to play an essential role in murine myometrial motility via activation of SUR2B and Kir6.2. PMID:27086859

  19. Speech of italian ambassador

    SciTech Connect

    2008-04-09

    L'ambassadeur italien (nom?)fait un discours sur l'aspect de la recherche au Cern, une organisation internationale qui a comme but la connaissance dans sa forme la plus pure et libre d'un intérêt planétaire. Il remet un prix au DG C.Rubbia qui lui remercie en français

  20. Impact de la varicocèle sur le volume testiculaire et les paramètres spermatiques

    PubMed Central

    Benazzouz, Mohamed Hicham; Essatara, Younes; El Sayegh, Hachem; Iken, Ali; Benslimane, Lounis; Nouini, Yassine

    2014-01-01

    Introduction La varicocèle est une pathologie masculine fréquente dont l'incidence est encore plus importante dans dans la population des hommes infertiles. Si ses mécanismes sont à ce jour incomplètement expliqués il semble acquis que la varicocèle peut être associée a une dysfonction testiculaire avec diminution du volume testiculaire et de la concentration en spermatozoïde de l’éjaculat. Méthodes Dans un premier temps nous exposons les résultats d'une étude rétrospective sur 5 ans (de Mars 2009 à Mars 2014), réalisée au service d'urologie A de l'hôpital Ibn Sina de Rabat et ayant comme objectif d’évaluer l'impact de la varicocèle palpable sur le volume testiculaire et les paramètres spermatiques. Tous les patients inclus dans notre étude avaient une varicocèle palpable. Dans un deuxième temps, et à travers une revue de la littérature nous discutons l'impact du traitement de la varicocèle sur la fertilité. Résultats 39 patients ont été inclus dans notre étude. L’âge moyen était de 29,71 ans et la varicocèle siégeait dans 89,74% des cas du coté gauche. Une atrophie testiculaire homolatérale à la varicocèle était retrouvée dans 7% des cas alors que des anomalies du spermogramme se voyaient dans 69,23% des cas. Conclusion L'impact de la varicocèle sur l'altération des paramètres spermatiques a été clairement établi bien que sa physio pathogénie ne soit pas bien élucidée. Le traitement chirurgical de la varicocèle semble indiqué chez les hommes infertiles présentant une varicocèle clinique et une altération significative du sperme. PMID:25918574

  1. Observing iodine monoxide from satellite

    NASA Astrophysics Data System (ADS)

    Schoenhardt, Anja; Richter, Andreas; Begoin, Mathias; Wittrock, Folkard; Burrows, John P.

    Iodine and iodine monoxide (IO) belong to the group of reactive halogen species, and they may impact on atmospheric chemical composition and the radiation budget. Vice versa, sur-rounding conditions may influence the emissions and pathways of iodine compounds. Although atmospheric amounts of iodine are typically fairly small, the impact may still be substantial. Iodine radicals are photolytically released from precursors and may then cause catalytic ozone depletion. In this reaction with ozone, IO is produced, a molecule which plays a central role in the iodine cycling. Via self reactions of IO, higher iodine oxides form and initiate the formation of new particles, which may change the atmospheric radiation balance. Apart from that, many living species, including human beings, vertebrates in general, but also micro-and macroalgae species, e.g., depend on the supply with iodine. Consequently, it is necessary to understand the cycling of iodine through the different components of the Earth system. Although increas-ing research effort in the form of field, laboratory and modeling studies has strongly improved our knowledge and understanding of iodine abundances and impact, still many open questions remain. The relevance of iodine on a global scale is not well known yet; sources are not well quantified and release processes are not fully understood. Since recently, IO may be observed from space by the SCIAMACHY instrument on the EN-VISAT satellite, which is in a near-polar, sun-synchronous orbit. Nadir observations from SCIAMACHY have been analysed for the IO absorption signature in the visible wavelength range for several mission years. IO amounts are typically close to the limit of detectability of SCIAMACHY. Detecting such small quantities, careful attention needs to be paid to system-atic errors, spectral correlations and resulting retrieval artefacts. Subsequently, appropriate temporal averaging is utilised to improve the signal-to-noise ratio. The resulting

  2. Mise à jour sur la vaccination contre l’herpès zoster

    PubMed Central

    Shapiro, Marla; Kvern, Brent; Watson, Peter; Guenther, Lyn; McElhaney, Janet; McGeer, Allison

    2011-01-01

    Résumé Objectif Répondre aux questions fréquentes concernant l’utilisation du nouveau vaccin contre l’herpès zoster (HZ). Sources de l’information Les résultats publiés d’études cliniques et d’autres études, les recommandations du Comité consultatif national de l’immunisation du Canada et de l’Advisory Committee on Immunization Practices des États-Unis; des données ont aussi été obtenues dans la monographie du produit approuvée par Santé Canada sur le vaccin. Principal message L’herpès zoster est causé par la réactivation du virus varicelle-zoster; l’algie post-zostérienne (APZ) est sa complication la plus fréquente et la plus grave. L’incidence de l’APZ après un zona est directement reliée à l’âge, notamment 50 % des personnes affectées de plus de 60 ans qui ont des douleurs persistantes non soulagées. Le vaccin à base de virus vivant contre le HZ réduit l’incidence du zona d’environ 50 % et de 2 tiers l’apparition des APZ. De plus, les symptômes sont atténués et de plus courte durée chez les personnes vaccinées. Le vaccin est contre-indiqué chez de nombreux patients immunodéprimés et pourrait ne pas être efficace chez les patients qui prennent des médicaments antiviraux qui agissent contre le virus HZ. Les médecins devraient être au courant des différentes recommandations touchant ces groupes. Conclusion Le vaccin contre le HZ est une mesure de prévention sécuritaire et efficace pour réduire le fardeau global et la gravité du zona chez les adultes plus âgés. Le vaccin semble rentable lorsqu’il est administré à des adultes de 60 ans et plus.

  3. Le cancer en Mauritanie : résultats sur 10 ans du registre hospitalier de Nouakchott

    PubMed Central

    Baba, Nacer Dine Ould Mohamed; Sauvaget, Catherine

    2013-01-01

    Le fardeau du cancer reste mal connu en Mauritanie. Il n'est basé que sur des extrapolations de l'incidence des cancers des pays avoisinants. Les données du registre de l'hôpital national permettent de décrire les cas avec un diagnostic histologique. Tous les cas de cancers enregistrés par le service d'anatomo-pathologie de l'hôpital national de Nouakchott de 2000 à 2009 ont été analysés. En 10 ans, 3305 prélèvements histologiques ont été analysés (hommes:42%, femmes:58%). Chez l'homme, le cancer le plus fréquemment analysé était le cancer de la peau (218 cas au total, 189 cas en excluant mélanome), suivi de la prostate (203), des cancers digestifs (179, colorectal et ‘sophage), et des lymphomes (151). Chez la femme, un quart des biopsies était des cancers du sein (485), suivi du col utérin (344), de la sphère gynécologique (218, ovaire et corps utérin), et de la peau (114). Les cancers du foie, du poumon ou de la vessie étaient peu fréquents. Ces résultats ne reflètent pas l'incidence ni l'actuel fardeau du cancer en Mauritanie puisque de nombreux patients diagnostiqués avec un cancer ne reçoivent pas d'examen anatomopathologique. Si, comme dans les pays avoisinants du Maroc et du Mali, les cancers du col et du sein sont les pathologies les plus fréquentes chez la femme, la distribution des cancers chez l'homme dans ce registre hospitalier diffère des résultats des registres de population du Maroc et du Mali où les cancers du poumon, du foie, de la prostate et de la vessie dominent. PMID:23785554

  4. Geochemistry of a Tertiary sedimentary phosphate deposit: Baja California Sur, Mexico

    USGS Publications Warehouse

    Piper, D.Z.

    1991-01-01

    The San Gregorio Formation in Baja California Sur, a phosphate-enriched sedimentary unit of late Oligocene to early Miocene age, has been analyzed in two areas (La Purisima and San Hilario) for its chemical composition (major oxides, Cu, Cd, Cr, Co, V, and rare-earth elements - REE) and isotopic composition (??18O and ??13C). A detrital and a marine component were determined from major oxides. The detrital component consists of an unaltered volcanic-ash fraction and a terrigenous clay-silt fraction. The marine component, which accumulated initially as biogenic and hydrogenous material, is now present as opal-A, opal-CT, CaCO3, organic matter, and an authigenic phosphate fraction, mostly pelletal and composed of the carbonate-fluorapatite mineral francolite. The minor elements have been partitioned into these components by assuming a constant composition for the two detrital fractions. The composition of the marine component of minor elements can then be interpreted by assuming that the stoichiometry of the original accumulating organic matter was equal to that of modern plankton. The Cu and Cd contents in the marine component of all rocks require that the seawater-derived fractions of these two metals were supplied to the seafloor solely by organic matter. Enrichments of Cr and V at both sites required an additional marine input. On the basis of their geochemistry in the modern ocean, Cr and V could have precipitated, or been adsorbed, onto settling particles from an O2 minimum zone in which the O2 content was low enough to promote denitrification rather than oxygen respiration. An enrichment of the REE, now within the apatite fraction, resulted from their adsorption onto particulates also in the O2 minimum zone and to the dissolution and alteration of biogenic phases (predominantly silica) within the sediment. Co and Fe2O3 show no enrichment above a detrital contribution. The ??18O-values of apatites from the La Purisima site are heavier than those of apatites

  5. The Palaeodiet of the Pericue Indians of the Cape Region of Baja California Sur, Mexico.

    NASA Astrophysics Data System (ADS)

    Beer, N.; Gonzalez, S.; Huddart, D.; Rosales-Lopez, A.; Lamb, A.

    2008-05-01

    The archaeology of the Pericue Indians inhabiting the Cape region of Baja California has long been an area of interest. The dolichocranic traits exhibited by this population have lead to suggestions that these people were a relic population of an early coastal migration into North America. The antiquity of directly dated Pericue human remains only reaches 3,000 B.P. with occupation sites dating back to 9,000 B.P. The site of Babisuri cave in Isla Espiritu Santo may demonstrate a very early human presence in Baja California Sur between 36,000 to 45,000 B.P. although the exact nature of this evidence is unclear. Increasing tourist development within this region threatens many archaeological sites particularly coastal shell middens and rock shelters. Current rescue excavations are yielding important information regarding many aspects of the culture of the Pericue Indians. Geochemical evidence of diet {d13C and d15N} taken from Pericue bone samples, modern and archaeological animals and modern plants is helping us to understand the complicated subsistence strategies of this group. Initial results highlight a complicated and diverse diet including marine and terrestrial resources, most likely exploited seasonally. Similarities between the diet of the Pericue and other nearby coastal Indian groups are clear and will be discussed. Pericue Indian material culture, combined with the exploitation of marine mammals and the construction of enormous shell mounds display parallels with other central and North American groups. The exploitation of marine mammals and the associated stone tools display striking similarities to the Chumash people of the Channel Islands of Coastal Southern California. Some of these cultural similarities will be highlighted in this presentation. Current genetic work is attempting to discover the nature of the similarities between the Chumash and Pericue groups as some cultural elements of each group have parallels with the other. Initial genetic

  6. Modelling impacts of offshore wind farms on trophic web: the Courseulles-sur-Mer case study

    NASA Astrophysics Data System (ADS)

    Raoux, Aurore; Pezy, Jean-Philippe; Dauvin, Jean-Claude; Tecchio, samuele; Degraer, Steven; Wilhelmsson, Dan; Niquil, Nathalie

    2016-04-01

    The French government is planning the construction of three offshore wind farms in Normandy. These offshore wind farms will integrate into an ecosystem already subject to a growing number of anthropogenic disturbances such as transportation, fishing, sediment deposit, and sediment extraction. The possible effects of this cumulative stressors on ecosystem functioning are still unknown, but they could impact their resilience, making them susceptible to changes from one stable state to another. Understanding the behaviour of these marine coastal complex systems is essential in order to anticipate potential state changes, and to implement conservation actions in a sustainable manner. Currently, there are no global and integrated studies on the effects of construction and exploitation of offshore wind farms. Moreover, approaches are generally focused on the conservation of some species or groups of species. Here, we develop a holistic and integrated view of ecosystem impacts through the use of trophic webs modelling tools. Trophic models describe the interaction between biological compartments at different trophic levels and are based on the quantification of flow of energy and matter in ecosystems. They allow the application of numerical methods for the characterization of emergent properties of the ecosystem, also called Ecological Network Analysis (ENA). These indices have been proposed as ecosystem health indicators as they have been demonstrated to be sensitive to different impacts on marine ecosystems. We present here in detail the strategy for analysing the potential environmental impacts of the construction of the Courseulles-sur-Mer offshore wind farm (Bay of Seine) such as the reef effect through the use of the Ecopath with Ecosim software. Similar Ecopath simulations will be made in the future on the Le Tréport offshore wind farm site. Results will contribute to a better knowledge of the impacts of the offshore wind farms on ecosystems. They also allow to

  7. Une arthrite septique sur prothèse totale de genou à Pasteurella multocida: à propos d'un cas

    PubMed Central

    Kouevidjin, Biova Teko; Bassinga, Jonathan Sylvanus

    2015-01-01

    Une arthrite septique sur PTG est due essentiellement au Staphylococcus aureus suivie des staphylocoques à coagulase négative, et les streptocoques. Au cours de ses 40 dernières années très peu de cas d'infection sur arthroplastie à Pasteurella multocida ont été rapporté. La présentation clinique n'a rien de spécifique.la contamination survient après une morsure, griffure ou léchage d'un chat. L'interrogatoire et l'examen bactériologique est la clé du diagnostique. Nous rapportons le cas d'une patiente de 84 ans qui présente une infection a Pasteurella multocida suite à une morsure du chat 06 jours au paravent. Elle a bénéficié d'une prise en charge chirurgicale par lavage et synovectomie et une bi-antibiothérapie avec bonne évolution. PMID:26523162

  8. From Bretonneau to therapeutic antibodies, from specificity to specific remedies, Saint-Cyr-Sur-Loire, France, November 19, 2012

    PubMed Central

    Marchand, Claire; Nouat, Romaric; Watier, Hervé

    2013-01-01

    Held on November 19, 2012 in Saint-Cyr-sur-Loire, France, the symposium “From Bretonneau to therapeutic antibodies, from specificity to specific remedies” focused on the historical development of antibodies as therapeutics, with an emphasis on the seminal work of the French physician Pierre-Fidèle Bretonneau (1778–1862). The morning session was devoted to discussion of the evolution of the concept of specificity in medicine, which started with an epistemological definition. The contributions of Bretonneau to the emergence of the concept of specificity, notably with his studies on diphtheria, and the subsequent development of antidiphtheric serotherapy in Europe during the period 1894–1898 were then presented in detail. The afternoon session began with a presentation on the role of French physiologists during the years 1860–1890 in establishing the basic concepts of specific immunity and the principles of serotherapy. The history of antivenom serotherapy, particularly its discovery by Césaire Phisalix, and the development of antilymphocyte globulins as successful transplantation drugs were then discussed. The symposium ended with the inauguration of a stele representing Bretonneau, who lived in Saint-Cyr-sur-Loire and died 150 y ago. PMID:23924799

  9. Sur la nature de la variabilite spectrale et photometrique periodique d'etoiles Wolf-Rayet apparemment isolees

    NASA Astrophysics Data System (ADS)

    Morel, Thierry

    Il est depuis longtemps suspecté que les étoiles Wolf-Rayet apparemment isolées présentant des variations périodiques dans le profil de leurs raies spectrales, en photométrie ou en polarimétrie sont associées à un compagnon dégénéré (étoile à neutron ou trou noir), et constituent ainsi une phase évolutive dont l'existence, bien que prédite par les modèles évolutifs des systèmes binaires massifs rapprochés, n'a pas encore été catégoriquement confirmée observationnellement. Cependant, de récentes études ayant trait à la variabilité spectrale des étoiles OB laissent émettre quelques doutes quant à la pertinence de ce modèle, en démontrant que des vents largement asphériques peuvent se développer dans les étoiles de type précoce. Le scénario alternatif serait donc de considérer que la variabilité périodique observée n'est pas due à la présence d'un compagnon dégénéré affectant la structure à grande échelle du vent de l'étoile Wolf-Rayet, mais est au contraire induite par la modulation par rotation d'un vent nettement anisotropique. Cet ouvrage présente les résultats d'un vaste programme d'observations spectroscopiques et photométriques (généralement simultanées) se proposant de lever l'ambiguïté sur la nature précise des étoiles Wolf-Rayet apparemment isolées dont la périodicité des variations est. soit depuis longtemps établie (WR 6), soit suspectée (WR 1, WR 134, WR 136). Notre étude a permis de confirmer l'existence d'une périodicité de 2.3 jours pour l'étoile WR 134. En outre, nous présentons des arguments mettant en doute l'éventuelle association de WR 6 et WR 134 avec un compagnon dégénéré. Alternativement, nous proposons que la variabilité périodique observée serait plutôt induite, à l'instar de nombreuses étoiles OB, par la rotation de structures azimutalement étendues dans le vent. Ce modèle est plus à même d'appréhender certains aspects de la variabilité, notamment la

  10. Methodologie de conception numerique d'un ventilateur helico-centrifuge basee sur l'emploi du calcul meridien

    NASA Astrophysics Data System (ADS)

    Lallier-Daniels, Dominic

    La conception de ventilateurs est souvent basée sur une méthodologie « essais/erreurs » d'amélioration de géométries existantes ainsi que sur l'expérience de design et les résultats expérimentaux cumulés par les entreprises. Cependant, cette méthodologie peut se révéler coûteuse en cas d'échec; même en cas de succès, des améliorations significatives en performance sont souvent difficiles, voire impossibles à obtenir. Le projet présent propose le développement et la validation d'une méthodologie de conception basée sur l'emploi du calcul méridien pour la conception préliminaire de turbomachines hélico-centrifuges (ou flux-mixte) et l'utilisation du calcul numérique d'écoulement fluides (CFD) pour la conception détaillée. La méthode de calcul méridien à la base du processus de conception proposé est d'abord présentée. Dans un premier temps, le cadre théorique est développé. Le calcul méridien demeurant fondamentalement un processus itératif, le processus de calcul est également présenté, incluant les méthodes numériques de calcul employée pour la résolution des équations fondamentales. Une validation du code méridien écrit dans le cadre du projet de maîtrise face à un algorithme de calcul méridien développé par l'auteur de la méthode ainsi qu'à des résultats de simulation numérique sur un code commercial est également réalisée. La méthodologie de conception de turbomachines développée dans le cadre de l'étude est ensuite présentée sous la forme d'une étude de cas pour un ventilateur hélico-centrifuge basé sur des spécifications fournies par le partenaire industriel Venmar. La méthodologie se divise en trois étapes: le calcul méridien est employé pour le pré-dimensionnement, suivi de simulations 2D de grilles d'aubes pour la conception détaillée des pales et finalement d'une analyse numérique 3D pour la validation et l'optimisation fine de la géométrie. Les résultats de calcul m

  11. Numerical modelling of circulation and dispersion processes in Boulogne-sur-Mer harbour (Eastern English Channel): sensitivity to physical forcing and harbour design

    NASA Astrophysics Data System (ADS)

    Jouanneau, Nicolas; Sentchev, Alexei; Dumas, Franck

    2013-12-01

    The MARS-3D model in conjunction with the particle tracking module Ichthyop is used to study circulation and tracer dynamics under a variety of forcing conditions in the eastern English Channel, and in the Boulogne-sur-Mer harbour (referred to hereafter as BLH). Results of hydrodynamic modelling are validated against the tidal gauge data, VHF radar surface velocities and ADCP measurements. Lagrangian tracking experiments are performed with passive particles to study tracer dispersal along the northern French coast, with special emphasis on the BLH. Simulations revealed an anticyclonic eddy generated in the harbour at rising tide. Tracers, released during flood tide at the Liane river mouth, move northward with powerful clockwise rotating current. After the high water, the current direction changes to westward, and tracers leave the harbour through the open boundary. During ebb tide, currents convergence along the western open boundary but no eddy is formed, surface currents inside the harbour are much weaker and the tracer excursion length is small. After the current reversal at low water, particles are advected shoreward resulting in a significant increase of the residence time of tracers released during ebb tide. The effect of wind on particle dispersion was found to be particularly strong. Under strong SW wind, the residence time of particles released during flood tide increases from 1.5 to 6 days. For release during ebb tide, SW wind weakens the southward tidally induced drift and thus the residence time decreases. Similar effects are observed when the freshwater inflow to the harbour is increased from 2 to 10 m3/s during the ebb tide flow. For flood tide conditions, the effect of freshwater inflow is less significant. We also demonstrate an example of innovative coastal management targeted at the reduction of the residence time of the pathogenic material accidentally released in the harbour.

  12. Arsenic content in groundwater from the southern part of the San Antonio-El Triunfo mining district, Baja California Sur, Mexico

    NASA Astrophysics Data System (ADS)

    Wurl, Jobst; Mendez-Rodriguez, Lía; Acosta-Vargas, Baudilio

    2014-10-01

    The San Antonio-El Triunfo mining district is located in a mountain region 60 km southeast of La Paz, the capital of the Mexican state of Baja California Sur. Mining activities, focused on gold and silver extraction, which began in the second half of the 18th century; the main activity took place between 1878 and 1911. The minerals were treated through the cyanide method, burned, and smelted. In effect between 800,000 and 1 million tons of mine waste materials were scattered in an area of approximately 350-400 km2. This area contains today several byproducts as a result from arsenopyrite oxidation, such as arsenolite (As2O3). The aim of this study was to analyze groundwater composition in order to define the actual concentrations of relevant parameters to detect ore mining contaminations, especially in respect to arsenic. In the autumn of 2010, 29 groundwater samples were obtained using flow-through bailer or down-hole pump methods, and a total of 37 variables were measured in each sample. Arsenic (dissolved) exceeded the values established by the World Health Organization (WHO, 2011) (0.01 mg/L) in 41% of the monitored sites. The maximum concentration of arsenic found in one observation well was 0.45 mg/L. Four water samples, which were characterized by elevated concentration of boron (max. conc. 9.5 mg/L), fluoride (max. conc. 3.25 mg/L) and alkaline pH values (>9), showed a composition typical for hydrothermal water. Because all four samples had arsenic concentration under 0.008 mg/L, we conclude that no significant impact of arsenic from hydrothermal fluids is found in the study area.

  13. Clair de lune sur le port de Boulogne: enquête sur un tableau de Manet, traduction d'un article de Donald W. Olson

    NASA Astrophysics Data System (ADS)

    Borg, Janet

    2016-10-01

    The 19th-century artist Edouard Manet created a spectacular nocturnal painting showing a full Moon over the harbor of Boulogne. Art historians have dated this work to either 1868 or 1869. Calculations of lunar phases, 19th-century maps and photographs of Boulogne harbor, the correspondence of the artist, and other clues allow us to determine a date and precise time when Manet observed this moonlit scene.

  14. Stratigraphy and geochronology of the Comondú Group near Loreto, Baja California sur, Mexico

    NASA Astrophysics Data System (ADS)

    Umhoefer, Paul J.; Dorsey, Rebecca J.; Willsey, Shawn; Mayer, Larry; Renne, Paul

    2001-10-01

    Upper Oligocene to Middle Miocene volcanic and sedimentary rocks in the Loreto region, Baja California Sur, are widely exposed and make up the Comondú Group as redefined here following McFall. The Comondú Group is part of a volcanic arc and forearc basin that formed along the northwestern margin of Mexico. Regional to detailed scale mapping, stratigraphic analysis, and geochronology in a 10-20-km-wide and 70-km-long belt from the gulf escarpment to the coast near Loreto reveal three main units in the Comondú Group and a composite thickness of ˜1.5-2 km. (1) The lower clastic unit (˜30-19 Ma) contains 200-300 m of fluvial sandstone and conglomerate with probable local eolian deposits and numerous felsic tuffs and basalt flows that accumulated in a forearc basin. (2) The middle breccia and lava flow unit (˜19-15 Ma) is up to 750 m thick and consists of massive andesite breccia that was deposited as proximal debris flows interbedded with minor andesite lava flows. (3) The upper lava flow and breccia unit (˜15-12 Ma) consists almost entirely of up to ˜600 meters of andesite lava flows a few kilometers west of Loreto that are part of a composite volcano. North and south of Loreto for up to 25 km, the unit is composed of andesite lava flows and massive andesite breccia that formed from thick debris flows near that and other volcanic centers. The three units of the Comondú Group in the Loreto area correlated with the Salto, Pelones, and Ricasón formations of the Bahı´a Concepción area. The lower clastic unit of this study is time equivalent to the marine San Gregorio, El Cien, and Isidro formations on the western and southern Baja California peninsula. The middle and upper units of the Loreto area are the proximal equivalent to the type section of the Comondú Group near the village of Comondú. During deposition of the lower part of the Comondú Group, the arc lay to the east on mainland Mexico in the Sierra Madre Occidental, and then migrated to the

  15. Late Quaternary Faulting along the San Juan de los Planes Fault Zone, Baja California Sur, Mexico

    NASA Astrophysics Data System (ADS)

    Busch, M. M.; Coyan, J. A.; Arrowsmith, J.; Maloney, S. J.; Gutierrez, G.; Umhoefer, P. J.

    2007-12-01

    As a result of continued distributed deformation in the Gulf Extensional Province along an oblique-divergent plate margin, active normal faulting is well manifest in southeastern Baja California. By characterizing normal-fault related deformation along the San Juan de los Planes fault zone (SJPFZ) southwest of La Paz, Baja California Sur we contribute to understanding the patterns and rates of faulting along the southwest gulf-margin fault system. The geometry, history, and rate of faulting provide constraints on the relative significance of gulf-margin deformation as compared to axial system deformation. The SJPFZ is a major north-trending structure in the southern Baja margin along which we focused our field efforts. These investigations included: a detailed strip map of the active fault zone, including delineation of active scarp traces and geomorphic surfaces on the hanging wall and footwall; fault scarp profiles; analysis of bedrock structures to better understand how the pattern and rate of strain varied during the development of this fault zone; and a gravity survey across the San Juan de los Planes basin to determine basin geometry and fault behavior. The map covers a N-S swath from the Gulf of California in the north to San Antonio in the south, an area ~45km long and ~1-4km wide. Bedrock along the SJPFZ varies from Cretaceous Las Cruces Granite in the north to Cretaceous Buena Mujer Tonalite in the south and is scarred by shear zones and brittle faults. The active scarp-forming fault juxtaposes bedrock in the footwall against Late Quaternary sandstone-conglomerate. This ~20m wide zone is highly fractured bedrock infused with carbonate. The northern ~12km of the SJPFZ, trending 200°, preserves discontinuous scarps 1-2km long and 1-3m high in Quaternary units. The scarps are separated by stretches of bedrock embayed by hundreds of meters-wide tongues of Quaternary sandstone-conglomerate, implying low Quaternary slip rate. Further south, ~2 km north of the

  16. Lipid Biomarkers for Methanogens in Hypersaline Cyanobacterial Mats for Guerrero Negro, Baja California Sur

    NASA Technical Reports Server (NTRS)

    Jahnke, Linda L.; Embaye, Tsegereda; Summons, Roger E.; Fonda, Mark (Technical Monitor)

    2002-01-01

    Analyses of sediments from the vicinity of active methane seeps have uncovered a particular suite of lipid biomarker patterns that characterize methane consuming archaea and their syntrophic, sulfate reducing partners. These isoprenoid biomarkers, largely identified by their anomalously light carbon isotopic signatures, have been a topic of intense research activity and are recorded in numerous methane-rich environments from Holocene to Cenozoic. This phenomenon has implications for depleted kerogens at 2.7 Ga on early Earth (Hinrichs 2002). In contrast, the lipid biosignatures of methane producing archaea are not readily identified through distinct isotopic labels and have received comparably little attention in analyses of archaea in environmental samples. Indeed, environmental analyses generally detect only free archaeal lipids, not the intact, polar molecules found in the membrane of living organisms. As part of the Ames NAI, the 'Early Microbial Ecosystem Research Group' (EMERG) is working to understand microbial processes in the hypersaline cyanobacterial mats growing in the salt evaporation ponds of the Exportadora de Sal at Guerrero Negro, Baja California Sur, Mexico. The aim of this study was to develop methods by which we could identify the organisms responsible for methane generation in this environment. While the ester-bound fatty acids, hopanoids and wax esters provide a means to identify most of the bacterial components of these mats, the archaea which Ere evidently present through genomic assays and the fact of intense methane production (Hoehler et al. 200l), have not been identified through their corresponding lipid signatures. Archaeal core lipids present a number of analytical challenges. The core lipids of methanogens comprise C20, C40 and sometimes C25 isoprenoid chains, linked through ether bonds to glycerol. As well as archaeal (C20), sn-2- and sn-3-hydroxyarchaeol are associated particularly with methylotrophic methanogens. Recently, we have

  17. Actes des journees de linguistique: Colloque sur la recherche etudiante (Proceedings of the Linguistics Conference: Colloquium on Student Research) (Quebec, Canada, March 18-19, 1988).

    ERIC Educational Resources Information Center

    Lepage, Danielle, Ed.; Dominik, Annette, Ed.

    Presentations by students at a colloquium on student research on the occasion of the 50th anniversary of the University of Laval's Faculty of Letters, March 18-19, 1988, include: "Une enquete sur la qualite du francais ecrit au Quebec"; "Amenagement linguistique et neologie"; "Analyse syntaxique des 'arrets et retours' en arabe morocain parle";…

  18. Conséquences des nouvelles formes de commande sur les matériaux de l'isolation statorique

    NASA Astrophysics Data System (ADS)

    Bellomo, J. P.; Lebey, Th.; Peltier, Fr.; Oraison, J. M.

    1997-05-01

    Use of inverter drive for rotating machines speed control leads to the application of new stress on stator insulation materials. The integrity of these materials under such stresses has therefore to be studied. Thanks to specially equipped motor, the different voltage shapes have been identified. Very short rise time fronts, large overvoltages and high oscillation frequencies are obtained. These voltages are then reproduced on laboratory samples (Polyethylene Terephtalate). The main result is the existence of trapped surface charges related both to the rise front value and to the existence of polar mechanisms in the material bulk. The consequences of this surface charge existence on the reliability of a real system are then discussed. L'utilisation de nouvelles formes de commande pour les machines à courant alternatif se traduit par l'apparition d'un nouveau type de contraintes sur les matériaux de l'isolation statorique. L'étude de leur comportement sous l'action de ce type de contraintes revêt un intérêt tout particulier pour la validation et la stabilité de ces systèmes dans le temps. Nous présentons, tout d'abord, ces différentes formes de tension identifiées à l'aide d'un moteur spécialement instrumenté. L'existence de fronts de tension très élevés, de surtensions importantes (jusqu'à 500V) et d'oscillations hautes fréquences (2MHz), est mise en évidence. La reproduction de ces contraintes en laboratoire sur des échantillons de polyesters (PolyÉthylène Térephthalate) permet alors de déterminer l'influence des formes de tension carrées sur les propriétés intrinsèques du matériau. Elle se traduit par l'existence d'une charge piégée en surface du diélectrique. Cette charge superficielle est associée, d'une part à l'existence de phénomènes de relaxation dans les matériaux étudiés et d'autre part à la valeur des fronts de tension appliqués. Pour finir, les conséquences possibles de l'existence de ces charges superficielles

  19. Nicotinamide-rich diet protects the heart against ischaemia-reperfusion in mice: a crucial role for cardiac SUR2A.

    PubMed

    Sukhodub, Andriy; Du, Qingyou; Jovanović, Sofija; Jovanović, Aleksandar

    2010-06-01

    It is a consensus view that a strategy to increase heart resistance to ischaemia-reperfusion is a warranted. Here, based on our previous study, we have hypothesized that a nicotinamide-rich diet could increase myocardial resistance to ischaemia-reperfusion. Therefore, the purpose of this study was to determine whether nicotinamide-rich diet would increase heart resistance to ischaemia-reperfusion and what is the underlying mechanism. Experiments have been done on mice on control and nicotinamide-rich diet (mice were a week on nicotinamide-rich diet) as well as on transgenic mice overexpressing SUR2A (SUR2A mice), a regulatory subunit of cardioprotective ATP-sensitive K(+) (K(ATP)) channels and their littermate controls (WT). The levels of mRNA in heart tissue were measured by real-time RT-PCR, whole heart and single cell resistance to ischaemia-reperfusion and severe hypoxia was measured by TTC staining and laser confocal microscopy, respectively. Nicotinamide-rich diet significantly decreased the size of myocardial infarction induced by ischaemia-reperfusion (from 42.5+/-4.6% of the area at risk zone in mice on control diet to 26.8+/-1.8% in mice on nicotinamide-rich diet, n=6-12, P=0.031). The cardioprotective effect of nicotinamide-rich diet was associated with 11.46+/-1.22 times (n=6) increased mRNA levels of SUR2A in the heart. HMR1098, a selective inhibitor of the sarcolemmal K(ATP) channels opening, abolished cardioprotection afforded by nicotinamide-rich diet. Transgenic mice with a sole increase in SUR2A expression had also increased cardiac resistance to ischaemia-reperfusion. We conclude that nicotinamide-rich diet up-regulate SUR2A and increases heart resistance to ischaemia-reperfusion.

  20. Rupture utérine sur utérus bicorne à 12 semaines d'aménorrhée: à propos d'un cas

    PubMed Central

    Itchimouh, Sanaa; Khabtou, Karima; Mahdaoui, Sakher; Boufettal, Houssine; Samouh, Naima

    2016-01-01

    La fréquence des malformations utérines ayant un impact sur la reproduction est difficile à apprécier. Leur mise en évidence nécessite un bilan spécifique (hystérosalpingographie, hystéroscopie, cœlioscopie). La fertilité spontanée peut être altérée en fonction du type d'anomalie utérine. Toutes ces anomalies peuvent avoir des répercussions sur l’évolution de la conception à type de fausses couches précoces et tardives, de grossesse extra utérine, de menace d'accouchement prématuré, d'accouchement prématuré, de pathologies vasculaires gravidiques et de retard de croissance intra-utérin. L'utérus bicorne est la plus connue des malformations et représente environ la moitié des anomalies de l'utérus. La survenue d'une telle grossesse constitue une situation à risque pouvant entraîner une mort maternelle, mais le diagnostic précoce et un bon suivi peut mener des grossesses à terme sur des utérus malformé. Le dépistage échographique devrait permettre la détection systématique de ce genre de cas afin de prendre préventivement les mesures qui s'imposent. Nous rapportons un cas de rupture utérine sur utérus bicorne unicervical sur grossesse à 12 semaines d'aménorrhée. PMID:27642490

  1. Testosterone protects female embryonic heart H9c2 cells against severe metabolic stress by activating estrogen receptors and up-regulating IES SUR2B.

    PubMed

    Ballantyne, Thomas; Du, Qingyou; Jovanović, Sofija; Neemo, Andrew; Holmes, Robert; Sinha, Sharabh; Jovanović, Aleksandar

    2013-02-01

    A recent clinical study demonstrated that a testosterone supplementation improves functional capacity in elderly female patients suffering from heart failure. These findings prompted us to consider possible mechanisms of testosterone-induced cardioprotection in females. To address this question we have used a pure female population of rat heart embryonic H9c2 cells. Pre-treatment of cells with testosterone for 24h significantly increased survival of H9c2 cells exposed to 2,4-dinitrophenol (DNP), an inhibitor of oxidative phosphorylation. These cells expressed low level of androgen receptors and the effect of testosterone was not modified by hydroxyflutamide, an antagonist of androgen receptor. In contrast, cyclohexamide, an inhibitor of protein biosynthesis, and tamoxifene, a partial agonist of estrogen receptors, abolished cardioprotection afforded by testosterone. In addition, finasteride, an inhibitor of 5α-reductase, and anastrazole, an inhibitor of α-aromatase, also blocked testosterone-induced cytoprotection. Real time RT-PCR revealed that testosterone did not regulate the expression of nine subunits and accessory proteins of sarcolemmal ATP-sensitive K(+) (K(ATP)) channels. On the other hand, testosterone, as well as 17β-estradiol, up-regulated a putative mitochondrial K(ATP) channel subunit, mitochondrial sulfonylurea receptor 2B intraexonics splice variant (IES SUR2B), without affecting expression of IES SUR2A. Tamoxifene inhibited testosterone-induced up-regulation of IES SUR2B without affecting IES SUR2A. In conclusion, this study has shown that testosterone protect female embryonic heart H9c2 cells against severe metabolic stress by its conversion into metabolites that activate estrogen receptors and up-regulate IES SUR2B.

  2. Une observation d'un goitre sur dysgénésie thyroïdienne pré-sternale

    PubMed Central

    Fanantenana, Herinirina Nicolas; Hasina, Rajaonarison Ny Ony Narindra Lova; Hery, Rafanomezantsoa; Claude, Rakotoarisoa Andriamihaja Jean; Ahmad, Ahmad

    2015-01-01

    L'hétérotopie thyroïdienne est une localisation anormale de tissus thyroïdiens normaux coexistant avec un organe normal et de localisation normale. Elle se distingue de l'ectopie thyroïdienne et d'une métastase du cancer de la thyroïde. Nous rapportons un cas d'hétérotopie thyroïdienne pré-sternale chez une femme de 65 ans afin de discuter le mécanisme de la migration de la thyroïde, le problème diagnostique et thérapeutique posé par cette topographie exceptionnelle. L'origine thyroïdienne de la masse est confirmée par l'histologie. Dans les lieux isolés, la chirurgie d'exérèse reste le seul moyen pour avoir le diagnostic et pour traiter les patients. PMID:26327954

  3. Regards sur l'evolution des theories de la traduction depuis vingt ans (Observations on the Evolution of Translation Theories Over the Past Twenty Years)

    ERIC Educational Resources Information Center

    Vinay, Jean-Paul

    1975-01-01

    This article discusses developments within the past twenty years in translation in North America and Europe, according to several approaches: theoretical stylistic, artistic, pedagogical, and computational. (Text is in French.) (AM)

  4. Etude de la Production des Mesons d* Sur le PIC de Resonance du Boson Z Observes AU Lep avec le Detecteur Opal

    NASA Astrophysics Data System (ADS)

    Przysiezniak, Helenka

    L'etude de la production des mesons D* est effectuee a partir d'evenements multihadroniques rm Z^0to q| q, avec des donnees prises en 1990, 1991 et 1992 avec le detecteur OPAL au LEP. La notation q definit les quarks des cinq saveurs pouvant etre observees au LEP: up (u), down (d), strange (s), charme (c), beaute (b). Les D* et les correlations D*-leptons sont identifiees et ces dernieres servent a effecteur une separation claire entre les evenements rm Z^0to b| b et Z^0to c| c. On mesure la distribution de la variable de fragmentation x_{rm D^ *}=E_{rm D^*}/E _{rm faisceau} pour les D* produits dans les evenements rm Z^0 to c| c. Elle est notee f _{rm cto D^*}. Ce resultat est a la base d'une publication OPAL (1), avec trois autres methodes de separation etudiees en parallele, donnat la premiere mesure OPAL de f _{rm cto D^*} qui soit independante de toute modelisation de la fragmentation des quarks lourds, ainsi qu'une mesure de Gamma_{rm c| c} parmi les plus precises effectuees a ce jour, ou Gamma_{rm c| c} est la largeur partielle de la desintegration du Z^0 en une paire cc. En ce qui concerne les resultats obtenus dans le cadre de cette these, la valeur moyenne de la distribution f_ {rm cto D^*}, notee < x_{rm cto D^*}>, est donnee par:< x_{rm cto D^*}>=0.530+/-0.027 +/-0.022ou la premiere erreur est statistique, et la seconde est systematique. On mesure aussi le taux de production des mesons D*, donnee par: {Gamma({rm Z^0to D^ *}X)overGamma_{rm hadrons}}=0.207+/-0.007+/-0.017 ou Gamma_{rm hadrons } est la largeur totale de la desintegration du Z^0 en paires de qq des cinq saveurs. La separation entre evenements rm Z^0to b| b et Z^0 to c| c, dans lesquels sont produits des D* se desintegrant selon rm D^ *to D^0pito (Kpi)pi, nous donne:(DIAGRAM, TABLE OR GRAPHIC OMITTED...PLEASE SEE DAI)La variable de fragmentation x_ {rm cto D^*} est utilisee pour tester les modeles des processes perturbatifs et non-perturbatifs qui entrent en jeu lors de la fragmentation des quarks b et c. On compare la distribution mesuree de la variable aux distributions des echantillons de donnees simulees, generees avec differentes fonctions de fragmentation (Peterson, Lund, Collins & Spiller, Kartvelishvili). On compare aussi la valeir moyenne de la distribution a celles mesurees dans d'autres experiences, a d'autres energies au centre de masse. On onserve que < x_{rm cto D^*} > decroi t avec l'energie au centre de masse. Ceci est une indication des violations d'echelle en ChromoDynamique Quantique. La mesure des taux de production sont en accord avec les autres mesures effectuees au LEP, dans ALEPH et DELPHI. Enfin, le resultat pour Gamma_ {| c}/Gamma_{ rm hadrons} est en accord avec les predictions du Modele Standard.

  5. Cancer développé sur dilatation kystique de la voie biliaire: à propos d’un cas

    PubMed Central

    Soufi, Mehdi; Lahlou, Mohammed Khalid; Chad, Bouziane

    2014-01-01

    Les auteurs rapportent un cas de dilatation kystique du cholédoque intra- pancréatique découvert chez une femme de 46 ans et compliqué d'un carcinome tubulo-papillaire n'envahissant pas le pancréas. Le traitement a consisté en une duodénopancréatectomie céphalique avec un curage ganglionnaire et anastomose hépatico-jéjunale; la survie était de 30 mois; les auteurs abordent les aspects radiologiques, anatomopathologiques, thérapeutiques et pronostiques de ces cancers développé sur dilatation kystique de la voie biliaire et discutent la place d'une radiothérapie complémentaire de la chirurgie susceptible d'améliorer la survie. PMID:25922635

  6. Influence du chrome et du niobium sur l'équilibre α-γ dans les aluminiures de titane

    NASA Astrophysics Data System (ADS)

    Daloz, D.; Hazotte, A.; Lacaze, J.; Charpentier, M.

    2004-12-01

    L’influence du chrome et du niobium sur les transformations et équilibres de phases des aluminiures de titane dans le domaine biphasé a/g est étudiée par analyse thermique différentielle, dilatomètrie, et métallographie quantitative après traitements thermiques suivis de trempe. Les compositions et les taux de phases à l’équilibre sont déterminés pour différentes températures du domaine biphasé a/g. Les résultats sont comparés aux calculs thermodynamiques réalisés à l’aide d’une banque de données relative aux intermétalliques de base Ti-Al.

  7. Reconnaissance geologic map of the Loreto and part of the San Janier quadrangles, Baja California Sur, Mexico

    USGS Publications Warehouse

    McLean, Hugh

    1988-01-01

    The Loreto area of Baja California Sur, Mexico, contains a diverse association of igneous, sedimentary, and metasedimentary rocks exposed in the foothills and arroyos between the Sierra La Giganta and Gulf of California. The Loreto area was selected for this study to examine the possible relation of the marine rocks to the opening of the Gulf of California, and to determine the stratigraphic and structural relations between basement rocks composed of granitic and prebatholithic rocks and overlying Tertiary (mainly Miocene) sedimentary and volcanic rocks, and by a sequence of Pliocene marine and nonmarine sedimentary rocks. The Pliocene marine rocks lie in a structural depression informally called here, the Loreto embayment. This geologic map and report stem from a cooperative agreement between the U.S. Geological Survey and the Consejo de Recursos Minerales of Mexico that was initiated in 1982.

  8. Oral Reading Observation System Observer's Training Manual.

    ERIC Educational Resources Information Center

    Brady, Mary Ella; And Others

    A self-instructional program for use by teachers of the handicapped, this training manual was developed to teach accurate coding with the Oral Reading Observation System (OROS)an observation system designed to code teacher-pupil verbal interaction during oral reading instruction. The body of the manual is organized to correspond to the nine…

  9. Influence des défauts de la structure du verre sur la résistance mécanique des fibres optiques

    NASA Astrophysics Data System (ADS)

    Chmel, A.; Baptizmanski, V. V.; Kharshak, A. A.

    1992-12-01

    For silica (pure and doped) optical fibers prepared from preforms irradiated by thermal neutrons and Ar^+ ions, the measurements of lifetime under transverse stress were carried out. It is found that the neutron bombardment leads to decrease of the lifetime and the strength of fiber while the ion implantation results in increasing of these parameters. The influence of particle irradiation on the glass strength is explained by the generation of structural defects which were observed by the infrared an Raman spectroscopy methods. The direction of the change of mechanical properties of fibers is determined by the type of defects and their distribution in the cross-section of fiber. Des préformes de fibres optiques de silice ont été exposées à un bombardement par des faisceaux de neutrons thermiques et d'ions Ar^+ à énergie de 40 keV afin d'engendrer des défauts de la structure respectivement dans le volume ou dans la couche superficielle des échantillons. Les fibres obtenues des préformes irradiées et non irradiées ont été mises en charge de flexion. On a déterminé leur temps de rupture sous diverses contraintes de traction sur la surface extérieure de la fibre en flexion. On a observé une diminution du temps de rupture des fibres après le bombardement neutronique et une augmentation après l'implantation ionique. L'analyse de la nature des défauts en faisant appel à la spectroscopie infrarouge et Raman a fait ressortir que l'irradiation aux ions entraînait essentiellement des liaisons chimiques dans une fine couche superficielle de l'échantillon alors que l'irradiation aux neutrons occasionnait une déformation des zones du réseau silicique dans toute la section de la préforme et de la fibre. L'amélioration de la résistance mécanique s'explique par une augmentation de la mobilité des éléments structuraux de la matrice de verre par suite d'une rupture partielle des liaisons chimiques et sa diminution par l'apparition de concentrateurs

  10. Ram Burn Observations (RAMBO)

    NASA Technical Reports Server (NTRS)

    2002-01-01

    Ram Burn Observations (RAMBO) is a Department of Defense experiment that observes shuttle Orbital Maneuvering System engine burns for the purpose of improving plume models. On STS-107 the appropriate sensors will observe selected rendezvous and orbit adjust burns.

  11. DRESS syndrome: à propos de trois observations

    PubMed Central

    Chebbi, Wafa; Souissi, Jihed; Chelli, Jihène; Larbi, Fatma; Zantour, Baha; Habib Sfar, Mohamed

    2014-01-01

    Le syndrome d'hypersensibilité médicamenteuse ou Drug Rash with Eosinophilia and Systemic Symptoms (DRESS) est une toxidermie rare mais sévère. Nous rapportons trois observations de DRESS syndromes secondaires à la prise de carbamazipine dans deux cas et de salazopyrine dans un cas. Le délai moyen entre la prise médicamenteuse et la survenue du DRESS syndrome était de six semaines. Le médicament incriminé était arrêté d'une façon définitive dans tous les cas. Une corticothérapie par voie générale était instaurée chez tous les patients devant l'atteinte hépatique sévère. L’évolution était favorable avec disparation des lésions cutanées et normalisation du bilan hépatique. Le diagnostic du syndrome DRESS doit être évoqué devant un tableau associant une éruption fébrile et des signes systémiques faisant suite à une prise médicamenteuse. La précocité du diagnostic est fondamentale pour l'arrêt définitif des médicaments suspects. Le traitement n'est pas bien codifié mais repose actuellement sur la corticothérapie générale. PMID:25810802

  12. Accident D’Electrisation et Hemorragie Cerebro-Meningee : A Propos D’une Observation

    PubMed Central

    Chaibdraa, A.; Medjellakh, M.S.; Saouli, A.; Bentakouk, M.C.

    2008-01-01

    Summary L'électrisation est un évènement accidentel qui diffère des autres pathologies occasionnant des brûlures graves, à cause de ses spécificités qui traduisent d'une part la destruction du revêtement cutané, mais également les effets directs ou indirects du courant électrique sur tout tissu de l'organisme rencontré lors de son passage, en particulier le tissu nerveux. Les manifestations neurologiques centrales sont nombreuses, en relation avec les effets de l'électricité sur le parenchyme cérébral ou une lésion associée à l'électrisation. Nous rapportons l'observation d'une hémorragie cérébro-meningée survenant au 3ème jour d'une électrisation grave. Cette complication est bien documentée dans la littérature traitant des accidents d'électrisation post-foudroiement. N'ayant pas rencontré de cas similaire publié lors des accidents dus au courant industriel, nous présentons cette observation, qui soulève le problème du mécanisme physiopathologique de survenue, difficile à trancher. PMID:21991125

  13. A Week of Observations

    ERIC Educational Resources Information Center

    Colasacco, Jenne

    2011-01-01

    Even the most effective teachers have room to grow, but it's not always easy for principals to give adequate guidance through short observations. High school principal Jenne Colasacco decided to bring more depth to her observations by observing each of her teachers during one class for an entire week. The new observation structure, which included…

  14. Ondes de surface transverses sur plaques piézoélectriques avec réseaux de bandes metalliques déposés sur les 2 faces

    NASA Astrophysics Data System (ADS)

    Ballandras, S.; Gavignet, E.; Bigler, E.

    1995-09-01

    A theoretical model has been implemented to study surface transverse waves propagating on piezoelectric plates of finite thickness with thin metal strip gratings on both sides. Calculations have been performed for AT-cuts of quartz of thickness varying from 140 to 120 μm. The spatial period of the gratings was fixed to 20 μm (acoustic wavelength equal to 40 μm). The dispersion curve relating the angular frequency to the wavenumber presents more than one stopband as found in the usual analyses on semi-infinite substrates. These multiple high-frequency stopbands allow to design and realize high stability resonators or highly sensitive sensors for gravimetry, accelerometer applications, etc. Un modèle théorique a été mis en œuvre pour l'étude des propriétés des ondes de surface transverses se propageant sur des plaques piézoélectriques d'épaisseur finie avec des réseaux de fines bandes métalliques déposés sur chaque face. Les calculs ont été effectués pour des plaques de quartz voisines de la coupe AT et d'épaisseur variant de 140 à 120 μm. La périodicité des réseaux en regard a été fixée à 20 μm (longueur d'onde acoustique 40 μm). La courbe de dispersion reliant la pulsation au nombre d'ondes présente plusieurs bandes d'arrêt incluant celle habituellement mise en évidence pour un substrat semi-infini. L'existence de ces multiples bandes d'arrêt haute fréquence ouvre de nouvelles perspectives pour la réalisation de résonateurs ultrastables ou de capteurs de très grande sensibilité gravimétrique, accélérométrique, etc.

  15. Early auroral observations

    NASA Astrophysics Data System (ADS)

    Silverman, S.

    1998-06-01

    Early auroral observations from Europe and Asia, and catalogs of these observations, are described and discussed. Cautions to be aware of when using these data include the dating of the observation, and the cultural context, especially for observations included in histories and annals as omens and portents. Specific attention is then paid to observations from classical Greece and Rome, the Middle East in biblical times, Asian annals, and the period from late antiquity through the medieval period.

  16. Active Crustal Deformation in the Area of San Carlos, Baja California Sur, Mexico as Shown by Data of Local Earthquake Sequences

    NASA Astrophysics Data System (ADS)

    Munguía, Luis; González-Escobar, Mario; Navarro, Miguel; Valdez, Tito; Mayer, Sergio; Aguirre, Alfredo; Wong, Victor; Luna, Manuel

    2015-12-01

    We analyzed earthquakes of sequences that occurred at different times near San Carlos, a town of approximately 5000 inhabitants. The seismic sequences happened during March-April 1989, October 2000-June 2001, and 5-15 February 2004 at about 200 km west of the Pacific-North America plate boundary. The strong shaking from initial earthquakes of the first two sequences prompted the installation of temporary seismic stations in the area. With data recorded by these stations, we found an earthquake distribution that is consistent with the northwest segment of the Santa Margarita fault. Both the focal depth, that seemed to increase in E-NE direction, and a composite fault-plane solution, obtained from polarity data of the small earthquakes, were also consistent with the main characteristics of that fault. We also found that our normal-faulting mechanism (east side down) was quite similar to centroid moment tensor solutions for earthquakes with M w 5.4 and 5.3 that occurred in the area in February 2004. It is likely, then, that these larger earthquakes also occurred along the Santa Margarita Fault. To get some insight into the regional stress pattern, we compared the above mechanisms with mechanisms reported for other earthquakes of the Pacific margin of Baja California Sur and the Gulf of California regions. We observed that focal mechanisms of the two regions have T axes of stress that plunge sub horizontally in E-NE average direction. The corresponding P axes have N-NW average trend, but for the Pacific earthquakes these axes plunge at angles that are ~35° larger than those for the Gulf earthquakes. These more vertically inclined P axes of compressive stress mean substantial oblique fault motions. The mixture of oblique and strike-slip components of fault motions, as the focal mechanisms show, confirms a transtensional stress regime for the region. Before this research, we knew little about the seismicity and styles of faulting in the area. Now we know that

  17. Active Crustal Deformation in the Area of San Carlos, Baja California Sur, Mexico as Shown by Data of Local Earthquake Sequences

    NASA Astrophysics Data System (ADS)

    Munguía, Luis; González-Escobar, Mario; Navarro, Miguel; Valdez, Tito; Mayer, Sergio; Aguirre, Alfredo; Wong, Victor; Luna, Manuel

    2016-10-01

    We analyzed earthquakes of sequences that occurred at different times near San Carlos, a town of approximately 5000 inhabitants. The seismic sequences happened during March-April 1989, October 2000-June 2001, and 5-15 February 2004 at about 200 km west of the Pacific-North America plate boundary. The strong shaking from initial earthquakes of the first two sequences prompted the installation of temporary seismic stations in the area. With data recorded by these stations, we found an earthquake distribution that is consistent with the northwest segment of the Santa Margarita fault. Both the focal depth, that seemed to increase in E-NE direction, and a composite fault-plane solution, obtained from polarity data of the small earthquakes, were also consistent with the main characteristics of that fault. We also found that our normal-faulting mechanism (east side down) was quite similar to centroid moment tensor solutions for earthquakes with M w 5.4 and 5.3 that occurred in the area in February 2004. It is likely, then, that these larger earthquakes also occurred along the Santa Margarita Fault. To get some insight into the regional stress pattern, we compared the above mechanisms with mechanisms reported for other earthquakes of the Pacific margin of Baja California Sur and the Gulf of California regions. We observed that focal mechanisms of the two regions have T axes of stress that plunge sub horizontally in E-NE average direction. The corresponding P axes have N-NW average trend, but for the Pacific earthquakes these axes plunge at angles that are ~35° larger than those for the Gulf earthquakes. These more vertically inclined P axes of compressive stress mean substantial oblique fault motions. The mixture of oblique and strike-slip components of fault motions, as the focal mechanisms show, confirms a transtensional stress regime for the region. Before this research, we knew little about the seismicity and styles of faulting in the area. Now we know that

  18. Volvulus gastrique aigu sur éventration diaphragmatique de l'adulte: à propos d'un cas et revue de la littérature

    PubMed Central

    Guèye, Mohamadou Lamine; Touré, Alpha Oumar; Thiam, Ousmane; Seck, Mamadou; Cissé, Mamadou; Kâ, Ousmane; Dieng, Madieng; Touré, Cheikh Tidiane

    2015-01-01

    Le volvulus gastrique aigu sur éventration diaphragmatique est une affection rare et une urgence diagnostique et thérapeutique. Sa présentation clinique est peu spécifique et la tomodensitométrie abdominale permet de confirmer le diagnostic. Nous rapportons le cas d'un patient de 22 ans qui présentaitun syndrome occlusif et une voussure épigastrique. A la radiographie de l'Abdomen Sans Préparation, on notait 2 niveaux hydro-aériques sous la coupole diaphragmatique gauche qui était surélevée. Une dévolvulation et une gastrectomie atypique ont été réalisées devant un volvulus gastrique aigu avec nécrose du fundus mis en évidence à la laparotomie. Les suites opératoires ont été simples. PMID:26161223

  19. Restauration fonctionnelle du rachis : effet du niveau initial de douleur sur les performances des sujets lombalgiques chroniques

    PubMed Central

    Caby, Isabelle; Olivier, N; Mendelek, F; Kheir, R Bou; Vanvelcenaher, J; Pelayo, P

    2014-01-01

    HISTORIQUE : La lombalgie chronique est une douleur lombaire persistante d’origine multifactorielle. Le niveau de douleur initial reste faiblement utilisé pour analyser et comparer les réponses des patients lombalgiques au programme de reconditionnement. OBJECTIFS : Apprécier et évaluer les réponses des sujets lombalgiques chroniques très douloureux à une prise en charge dynamique et intensive. MÉTHODOLOGIE : 144 sujets atteints de lombalgie chronique ont été inclus dans un programme de restauration fonctionnelle du rachis de 5 semaines. Les sujets ont été classés en deux groupes de niveau de douleur: un groupe atteint de douleur sévère (n = 28) et un groupe atteint de douleur légère à modérée (n = 106). L’ensemble des sujets ont bénéficié d’une prise en charge identique comprenant principalement de la kinésithérapie, de l’ergothérapie, du reconditionnement musculaire et cardio-vasculaire ainsi qu’un suivi psychologique. Les paramètres physiques (flexibilité, force musculaire) et psychologiques (qualité de vie) ont été mesurés avant (T0) et après le programme (T5sem). RÉSULTATS : L’ensemble des performances physiques et fonctionnelles des sujets très douloureux sont moins bonnes et le retentissement de la lombalgie sur la qualité de vie, pour ces mêmes sujets, est majoré à T0. Toutes les différences significatives constatées à T0 entre les deux groupes s’effacent à T5sem. CONCLUSIONS : Les sujets lombalgiques chroniques très douloureux répondent favorablement au programme dynamique et intensif. L’intensité douloureuse de la lombalgie n’aurait pas d’effet sur les réponses au programme. La restauration fonctionnelle du rachis apporterait aux sujets la possibilité de mieux gérer leur douleur quel que soit son niveau. PMID:25299476

  20. Computing by Observing Changes

    NASA Astrophysics Data System (ADS)

    Cavaliere, Matteo; Leupold, Peter

    Computing by Observing is a paradigm for the implementation of models of Natural Computing. It was inspired by the setup of experiments in biochemistry. One central feature is an observer that translates the evolution of an underlying observed system into sequences over a finite alphabet. We take a step toward more realistic observers by allowing them to notice only an occurring change in the observed system rather than to read the system's entire configuration. Compared to previous implementations of the Computing by Observing paradigm, this decreases the computational power; but with relatively simple systems we still obtain the language class generated by matrix grammars.

  1. Détermination expérimentale de la résistance thermique d'interface d'un dépôt métallique submicronique sur son substrat

    NASA Astrophysics Data System (ADS)

    Hmina, N.; Scudeller, Y.

    1995-06-01

    de la résistance électrique du dépôt. La détection à large bande passante (25 MHz) assure une bonne restitution du signal. Celui-ci est filtré numériquement pour être ensuite analysé. De très faibles résistances, comprises entre 10^{-8} et 10^{-6} m^2 K/W, peuvent être détectées lorsque l'observation des variations de température s'effectue avant la première microseconde. Le principe de la méthode et le dispositif expérimental sont présentés. La sensibilité de la méthode est analysée en détail. Des résultats, obtenus sur des dépôts de 200 à 600 nm de cuivre pulvérisés sur un substrat de verre de Silice, sont présentés. Des résistances d'interfaces de l'ordre de 10^{-7} m^2 K/W ont été identifiées avec une précision d'environ 30 %.

  2. Polyhedral Observation Cupola

    NASA Technical Reports Server (NTRS)

    Edelstein, Karen S.; Valle, Gerald D.

    1990-01-01

    Strong, lightweight structure includes facets with windows. Report describes concept for observation cupola for Space Station Freedom. Cupola used by crewmembers to observe docking of Space Shuttle, servicing of payloads, extravehicular activity, and other operations in which they could help by observing. Includes computer-generated pictures realistically depicting crewmembers' positions, workstation positions, and views through various windows.

  3. Teacher Observation Scales.

    ERIC Educational Resources Information Center

    Purdue Univ., Lafayette, IN. Educational Research Center.

    The Teacher Observation Scales include four instruments: Observer Rating Scale (ORS), Reading Strategies Check List, Arithmetic Strategies Check List, and Classroom Description. These instruments utilize trained observers to describe the teaching behavior, instructional strategies and physical characteristics in each classroom. On the ORS, teacher…

  4. L'Univers bute sur l'âge du fer

    NASA Astrophysics Data System (ADS)

    Bonnet-Bidaud, J. M.

    2003-07-01

    La découverte d'un quasar très lointain, apparu dans l'Univers très jeune, bien plus chargé en fer que ne le prévoit le Big Bang, sème la perplexité chez les cosmologistes. Faut-il revoir la théorie ou attendre d'autres observations?

  5. Evaluating Reanalysis - Independent Observations and Observation Independence

    NASA Astrophysics Data System (ADS)

    Wahl, S.; Bollmeyer, C.; Danek, C.; Friederichs, P.; Keller, J. D.; Ohlwein, C.

    2014-12-01

    Reanalyses on global to regional scales are widely used for validation of meteorological or hydrological models and for many climate applications. However, the evaluation of the reanalyses itself is still a crucial task. A major challenge is the lack of independent observations, since most of the available observational data is already included, e. g. by the data assimilation scheme. Here, we focus on the evaluation of dynamical reanalyses which are obtained by using numerical weather prediction models with a fixed data assimilation scheme. Precipitation is generally not assimilated in dynamical reanalyses (except for e.g. latent heat nudging) and thereby provides valuable data for the evaluation of reanalysis. Since precipitation results from the complex dynamical and microphysical atmospheric processes, an accurate representation of precipitation is often used as an indicator for a good model performance. Here, we use independent observations of daily precipitation accumulations from European rain gauges (E-OBS) of the years 2008 and 2009 for the intercomparison of various regional reanalyses products for the European CORDEX domain (Hirlam reanalysis at 0.2°, Metoffice UM reanalysis at 0.11°, COSMO reanalysis at 0.055°). This allows for assessing the benefits of increased horizontal resolution compared to global reanalyses. Furthermore, the effect of latent heat nudging (assimilation of radar-derived rain rates) is investigated using an experimental setup of the COSMO reanalysis with 6km and 2km resolution for summer 2011. Further, we present an observation independent evaluation based on kinetic energy spectra. Such spectra should follow a k-3 dependence of the wave number k for the larger scale, and a k-5/3 dependence on the mesoscale. We compare the spectra of the aforementioned regional reanalyses in order to investigate the general capability of the reanalyses to resolve events on the mesoscale (e.g. effective resolution). The intercomparison and

  6. Chaetognatha in the Bahía Magdalena lagoon complex, Baja California Sur, México: species composition and assemblages.

    PubMed

    Cota Meza, M S

    2011-07-01

    The chaetognaths from 187 zooplankton samples collected from the Bahia Magdalena lagoon complex, Baja California Sur, Mexico during March, June, July, August, September, November, and December 1982 were studied. Twelve species belonging to two genera were identified. Sagitta euneritica and S. enflata were the most abundant and most frequent species with maximum abundance in July (40,000 org/100 m(3) and 6100 org/100 m(3) respectively). Sagitta pacifica, S. regularis and S. pseudoserratodentata were stenothermic (21 to 25 degrees C), whereas the rest of the species were eurythermic (15.5 to 29.5 degrees C). Sagitta euneritica contributed considerably to the zooplanktonic biomass, increasing the density in particular in BahíaAlmejas. The analysis of the species assemblages (Morisita index) showed that S. pacifica and S. regularis interact more frequently in August when there is a change of the water masses that converge in this zone during summer, when the California Countercurrent predominates. The composition of taxa during winter is characterized by the dominance of S. euneritica. Entering the warm period, an abrupt change occurs in taxa composition of the three zones studied: channels, Bahía Magdalena, and BahíaAlmejas. The amplitude and distribution of S. peruviana was influenced possibility by the oceanographic conditions of ENSO 1982. PMID:22315819

  7. Baseline heavy metals and metalloid values in blood of loggerhead turtles (Caretta caretta) from Baja California Sur, Mexico.

    PubMed

    Ley-Quiñónez, C; Zavala-Norzagaray, A A; Espinosa-Carreón, T L; Peckham, H; Marquez-Herrera, C; Campos-Villegas, L; Aguirre, A A

    2011-09-01

    Environmental pollution due to heavy metals is having an increased impact on marine wildlife accentuated by anthropogenic changes in the planet including overfishing, agricultural runoff and marine emerging infectious diseases. Sea turtles are considered sentinels of ecological health in marine ecosystems. The objective of this study was to determine baseline concentrations of zinc, cadmium, copper, nickel, selenium, manganese, mercury and lead in blood of 22 clinically healthy, loggerhead turtles (Caretta caretta), captured for several reasons in Puerto López Mateos, Baja California Sur, Mexico. Zinc was the most prevalent metal in blood (41.89 μg g⁻¹), followed by Selenium (10.92 μg g⁻¹). The mean concentration of toxic metal Cadmium was 6.12 μg g⁻¹ and 1.01μg g⁻¹ respectively. Mean concentrations of metals followed this pattern: Zn>Se>Ni>Cu>Mn>Cd>Pb and Hg. We can conclude that blood is an excellent tissue to measure in relatively non-invasive way baseline values of heavy metals in Caretta caretta. PMID:21788056

  8. SUR1 Receptor Interaction with Hesperidin and Linarin Predicts Possible Mechanisms of Action of Valeriana officinalis in Parkinson

    PubMed Central

    Santos, Gesivaldo; Giraldez-Alvarez, Lisandro Diego; Ávila-Rodriguez, Marco; Capani, Francisco; Galembeck, Eduardo; Neto, Aristóteles Gôes; Barreto, George E.; Andrade, Bruno

    2016-01-01

    Parkinson’s disease (PD) is one of the most common neurodegenerative disorders. A theoretical approach of our previous experiments reporting the cytoprotective effects of the Valeriana officinalis compounds extract for PD is suggested. In addiction to considering the PD as a result of mitochondrial metabolic imbalance and oxidative stress, such as in our previous in vitro model of rotenone, in the present manuscript we added a genomic approach to evaluate the possible underlying mechanisms of the effect of the plant extract. Microarray of substantia nigra (SN) genome obtained from Allen Brain Institute was analyzed using gene set enrichment analysis to build a network of hub genes implicated in PD. Proteins transcribed from hub genes and their ligands selected by search ensemble approach algorithm were subjected to molecular docking studies, as well as 20 ns Molecular Dynamics (MD) using a Molecular Mechanic Poison/Boltzman Surface Area (MMPBSA) protocol. Our results bring a new approach to Valeriana officinalis extract, and suggest that hesperidin, and probably linarin are able to relieve effects of oxidative stress during ATP depletion due to its ability to binding SUR1. In addition, the key role of valerenic acid and apigenin is possibly related to prevent cortical hyperexcitation by inducing neuronal cells from SN to release GABA on brain stem. Thus, under hyperexcitability, oxidative stress, asphyxia and/or ATP depletion, Valeriana officinalis may trigger different mechanisms to provide neuronal cell protection. PMID:27199743

  9. MIS3 to late Holocene Palaeo-ice Thickness Constraints of Glacier Viedma, Hielo Patagonico Sur, Southern South America

    NASA Astrophysics Data System (ADS)

    Geiger, A.; Fabel, D.; Glasser, N. F.

    2014-12-01

    Southern South America is the only landmass intersecting the southern westerly winds (SWW), which critically shape southern hemispheric and global climate. At present palaeo-climatic datasets stretching the 3000 km of SWW influence are in latitudinal disagreement, suggesting a complex picture of SWW palaeo-behavior. In order to unravel the nature of the SWW over the last glacial cycle, a tighter grid of sensitive palaeo-proxies in the region is required. The work presented here is based on the palaeo-glaciology of the Viedma outlet (49°S, 72°W), the second largest glacier draining the Hielo Patagonico Sur (HPS). This locality corresponds to the present day center of the precipitation bearing SWW in southern South America, which are a key factor in maintaining the HPS. Any variation in SWW strength or location has a direct impact on glacial expansion in the region, hence palaeo-glacial geometries can provide key insights into SWW dynamics. Palaeo-ice surface, thickness and thinning rates spanning MIS3 to the late Holocene are presented based on 16 Be-10 exposure ages along three vertical transects covering the accumulation and ablation areas of glacier Viedma. Results indicate a maximum ice thickness over MIS3, a thickening over the Antarctic Cold Reversal (ACR), which overprinted the vertical expression of the LGM, and progressive ice surface lowering from the middle to the late Holocene. The palaeo-climatic implications will be discussed, particularly with focus on SWW positioning and behavior.

  10. Biological influences on modern sulfates: Textures and composition of gypsum deposits from Guerrero Negro, Baja California Sur, Mexico

    NASA Astrophysics Data System (ADS)

    Vogel, Marilyn B.; Des Marais, David J.; Parenteau, Mary N.; Jahnke, Linda L.; Turk, Kendra A.; Kubo, Michael D. Y.

    2010-01-01

    Gypsum (CaSO 4·2H 2O) deposits from a range of sedimentary environments at Guerrero Negro, Baja California Sur, Mexico were investigated for microscale texture and composition in order to differentiate features formed under substantial microbial influence from those for which microbial effects were relatively minor or absent. Gypsum deposits were classified according to their sedimentary environment, textures, crystal habit, brine composition and other geochemical factors. The environments studied included subaqueous sediments in anchialine pools and in solar salterns, as well as subsurface sediments of mudflats and saltpans. Gypsum that developed in the apparent absence of biofilms included crystals precipitated in the water column and subsedimentary discs that precipitated from phreatic brines. Subsedimentary gypsum developed in sabkha environments exhibited a sinuous microtexture and poikilitically enclosed detrital particles. Water column precipitates had euhedral prismatic habits and extensive penetrative twinning. Gypsum deposits influenced by biofilms included bottom nucleated crusts and gypsolites developing in anchialine pools and saltern ponds. Gypsum precipitating within benthic biofilms, and in biofilms within subaerial sediment surfaces provided compelling evidence of biological influences on crystal textures and habits. This evidence included irregular, high relief surface textures, accessory minerals (S°, Ca-carbonate, Sr/Ca-sulfate and Mg-hydroxide) and distinctive crystal habits such as equant forms and crystals having distorted prism faces.

  11. Syndrome de larva migrans cutanée sur pied malformé (à propos d'un cas)

    PubMed Central

    Benbella, Imane; Khalki, Hanane; Lahmadi, Khalid; Kouara, Sara; Abbadi, Abderrahim; Er-rami, Mohammed

    2016-01-01

    Le syndrome de larva migrans cutanée est une dermite sous cutanée causée par des larves d'ankylostomes d'animaux en impasse parasitaire chez l'homme. L'infestation transcutanée est favorisée par le contact avec le sol contaminé par les larves du parasite. Nous rapportons le cas d'un nourrisson de 15 mois, originaire de Guinée-Bissau, atteint d'un syndrome de larva migrans cutanée sur un pied malformé. Cette malformation sous forme d'une syndactylie associée à une tuméfaction du pied, était à l'origine d'un retard d'acquisition de la station debout. De même, on a rapporté une notion de pieds nus, vue la difficulté de chausser le pied malformé du patient. Tous ces facteurs auraient contribués à favoriser l'infestation du malade par les larves du nématode. PMID:27217876

  12. Rupture utérine spontanée sur léiomyosarcome utérin

    PubMed Central

    Boussouni, Khouloud; Benoulaid, Meryem; Dafiri, Rachida

    2016-01-01

    Les sarcomes utérins sont des cancers rares caractérisés par leur polymorphisme clinique et histologique. Ce sont des tumeurs malignes de mauvais pronostic. Ils se révèlent, généralement, par des symptômes non spécifiques à type de douleurs pelviennes, métrorragies. Un tableau d'abdomen aigu avec hémopneumopéritoine est une présentation rare. Nous rapportons le cas d'un léiomyosarcome utérin qui s'est manifesté par une péritonite aigue généralisée inaugurale chez une femme de 43 ans. Le diagnostic de perforation utérine sur tumeur maligne a été suspecté par l'imagerie préopératoire en urgence (échographie et TDM) et confirmé histologiquement. PMID:27642425

  13. Baseline heavy metals and metalloid values in blood of loggerhead turtles (Caretta caretta) from Baja California Sur, Mexico.

    PubMed

    Ley-Quiñónez, C; Zavala-Norzagaray, A A; Espinosa-Carreón, T L; Peckham, H; Marquez-Herrera, C; Campos-Villegas, L; Aguirre, A A

    2011-09-01

    Environmental pollution due to heavy metals is having an increased impact on marine wildlife accentuated by anthropogenic changes in the planet including overfishing, agricultural runoff and marine emerging infectious diseases. Sea turtles are considered sentinels of ecological health in marine ecosystems. The objective of this study was to determine baseline concentrations of zinc, cadmium, copper, nickel, selenium, manganese, mercury and lead in blood of 22 clinically healthy, loggerhead turtles (Caretta caretta), captured for several reasons in Puerto López Mateos, Baja California Sur, Mexico. Zinc was the most prevalent metal in blood (41.89 μg g⁻¹), followed by Selenium (10.92 μg g⁻¹). The mean concentration of toxic metal Cadmium was 6.12 μg g⁻¹ and 1.01μg g⁻¹ respectively. Mean concentrations of metals followed this pattern: Zn>Se>Ni>Cu>Mn>Cd>Pb and Hg. We can conclude that blood is an excellent tissue to measure in relatively non-invasive way baseline values of heavy metals in Caretta caretta.

  14. Evolution de films de cuivre sur un substrat de cordiérite au cours de traitements thermiques

    NASA Astrophysics Data System (ADS)

    Guille, Jean-Louis; Gondolf, Marc

    1993-04-01

    Copper films were applied on low sintering temperature cordierite substrates either by sputtering or screen printing. Their behaviour during thermal treatments was studied as a function of various parameters : deposition technique, thickness, firing atmosphere, physical state of the substrate (green or sintered). Films were most often broken during the treatment. In the case of screen printed films the effects of an oxydation-reduction cycle of copper are pointed out. Des films de cuivre ont été déposés sur un substrat de cordiérite à basse température de frittage par deux techniques, pulvérisation cathodique et sérigraphie. On étudie leur comportement au cours de traitements thermiques en fonction de différents paramètres : technique de déposition, épaisseur, atmosphère de traitement, état physique du substrat (cru ou fritté). On constate le plus souvent une fragmentation du film. Dans le cas des films sérigraphiés on met en évidence les effets dus à l'oxydation et à la réduction du cuivre.

  15. Observational projects in Serbia

    NASA Astrophysics Data System (ADS)

    Vince, O.; Cvetković, Z.; Pavlović, R.; Damljanović, G.; Djurašević, G.

    2014-03-01

    A new era of astronomical observations in Serbia started in 2010, when a 60 cm telescope was installed on the summit of the mountain Vidojevica. Despite the small number of active observers and all the problems that usually follows the usage of a new instrument, we developed several observational projects, joined several international observational networks and follow-up projects. In this paper, we will shortly introduce all the projects and people involved in them, as well as the instruments that are used for observations.

  16. Protein kinase C modulation of recombinant ATP-sensitive K(+) channels composed of Kir6.1 and/or Kir6.2 expressed with SUR2B.

    PubMed

    Thorneloe, Kevin S; Maruyama, Yoshiaki; Malcolm, A Todd; Light, Peter E; Walsh, Michael P; Cole, William C

    2002-05-15

    The molecular identity of smooth muscle ATP-sensitive K(+) channels (K(ATP)) is not established with certainty. Patch clamp methods were employed to determine if recombinant K(ATP) channels composed of Kir6.1 and SUR2B subunits expressed by human embryonic kidney (HEK293) cells share an identical modulation by protein kinase C (PKC) with the vascular K(NDP) subtype of K(ATP) channel. The open probability of Kir6.1/SUR2B channels was determined before and after sequential exposure to pinacidil (50 microM) and the combination of pinacidil and phorbol 12,13-dibutyrate (PdBu; 50 nM). Treatment with PdBu caused a decline in channel activity, but this was not seen with an inactive phorbol ester, 4 alpha-phorbol 12,13-didecanoate (PdDe; 50 nM). Angiotensin II (0.1 microM) induced a similar inhibition of Kir6.1/SUR2B channels in cells expressing angiotensin AT(1) receptors. The effects of PdBu and angiotensin II were blocked by the PKC inhibitor, chelerythrine (3 microM). Purified PKC inhibited Kir6.1/SUR2B activity (in 0.5 mM ATP/ 0.5 mM ADP), and the inhibition was blocked by a specific peptide inhibitor of PKC, PKC(19-31). In contrast, PdBu increased the activity of recombinant K(ATP) channels composed of Kir6.2 and SUR2B, or the combination of Kir6.1, Kir6.2 and SUR2B subunits. The results indicate that the modulation by PKC of Kir6.1/SUR2B, but not Kir6.2/SUR2B or Kir6.1-Kir6.2/SUR2B channel gating mimics that of native vascular K(NDP) channels. Physiological inhibition of vascular K(ATP) current by vasoconstrictors which utilize intracellular signalling cascades involving PKC is concluded to involve the modulation of K(NDP) channel complexes composed of four Kir6.1 and their associated SUR2B subunits.

  17. Les effets du travail en equipe dans l'apprentissage par projets sur la motivation des etudiantes et des etudiants en formation des ingenieurs

    NASA Astrophysics Data System (ADS)

    Fernandez, Nicolas

    Les representants des secteurs industriels et les, milieux professionnels en Amerique du Nord reprochaient aux universites de former des ingenieurs avec peu d'experience pratique en resolution de problemes et en conception. Quelques programmes de genie ont alors mis en place le travail en equipe dans l'apprentissage par projets. Beaucoup d'ecrits font valoir les benefices de l'apprentissage par projets sur la motivation des etudiants. Or, ces benefices commencent a peine a faire l'objet de recherches visant a produire des donnees probantes a ce sujet. Les travaux sur la motivation en contexte d'apprentissage et les modeles theoriques developpes sont issus d'environnements d'apprentissage marques par l'enseignement magistral. Le modele de la valeur attendue de la tache (Eccles et Wigfield, 1995; Neuville, 2004) et le modele du systeme-groupe (St-Arnaud, 2008) ont ete retenus pour mesurer les effets du travail en equipe dans l'apprentissage par projets sur la motivation. La recherche visait aussi a approfondir et a nuancer la comprehension de la motivation des etudiants universitaires apprenant en contexte innovant. Les sujets constituent des etudiants (n=100) travaillant sur des projets d'integration au cours des trois sessions initiales du programme de genie mecanique d'une universite canadienne. L'analyse de regression multiple revele que les construits de la motivation expliquent un tiers de la variance de l'engagement academique dans la realisation du projet d'integration. Les perceptions de l' "expectancy", de la valeur intrinseque et utilitaire sont les determinants principaux de l'engagement des etudiants. L'analyse de variance multivariee a mesures repetees indique que la motivation des etudiants pour le travail sur les projets d'integration a augmente au cours des trois sessions initiales du parcours de formation. Finalement, malgre l'absence d'interaction significative entre les variables de motivation et de l'equipe, les reponses des sujets indiquent une

  18. BOOK REVIEW: Observational Cosmology Observational Cosmology

    NASA Astrophysics Data System (ADS)

    Howell, Dale Andrew

    2013-04-01

    Observational Cosmology by Stephen Serjeant fills a niche that was underserved in the textbook market: an up-to-date, thorough cosmology textbook focused on observations, aimed at advanced undergraduates. Not everything about the book is perfect - some subjects get short shrift, in some cases jargon dominates, and there are too few exercises. Still, on the whole, the book is a welcome addition. For decades, the classic textbooks of cosmology have focused on theory. But for every Sunyaev-Zel'dovich effect there is a Butcher-Oemler effect; there are as many cosmological phenomena established by observations, and only explained later by theory, as there were predicted by theory and confirmed by observations. In fact, in the last decade, there has been an explosion of new cosmological findings driven by observations. Some are so new that you won't find them mentioned in books just a few years old. So it is not just refreshing to see a book that reflects the new realities of cosmology, it is vital, if students are to truly stay up on a field that has widened in scope considerably. Observational Cosmology is filled with full-color images, and graphs from the latest experiments. How exciting it is that we live in an era where satellites and large experiments have gathered so much data to reveal astounding details about the origin of the universe and its evolution. To have all the latest data gathered together and explained in one book will be a revelation to students. In fact, at times it was to me. I've picked up modern cosmological knowledge through a patchwork of reading papers, going to colloquia, and serving on grant and telescope allocation panels. To go back and see them explained from square one, and summarized succinctly, filled in quite a few gaps in my own knowledge and corrected a few misconceptions I'd acquired along the way. To make room for all these graphs and observational details, a few things had to be left out. For one, there are few derivations

  19. Integrating Models and Observations

    NASA Technical Reports Server (NTRS)

    Womebarger, Amy

    2011-01-01

    For the past ten years, the coronal loops community has held bi-annual workshops to discuss the analysis of coronal loop observations and the latest efforts to model the loop structures. During this time, several heating scenarios have been proposed to explain loop observations. These heating scenarios rely on different heating frequencies, locations, and durations, as well as different loop sub-structure. Often the scenarios are developed to explain an observation, hence all heating scenarios match some observational criteria. The key to discriminating between the competing heating scenarios is to first identify the distinguishing observables. For instance, both effectively steady and nanoflare-heating scenarios can produce quasi-steady intensities. Observing quasi-steady intensities, then, does not help determine which heating scenario is most likely. These heating scenarios may, however, predict different velocities or different emission measure distributions. In this talk, I will discuss a few of the expected observations for some simple heating scenarios. I will ask the modeling community to calculate similar observations for the different heating scenarios to generate a standard list of expected observations. After the community develops this list, comparisons with actual loop observations can then distinguish the most likely heating scenario.

  20. Observing Double Stars

    NASA Astrophysics Data System (ADS)

    Genet, Russell M.; Fulton, B. J.; Bianco, Federica B.; Martinez, John; Baxter, John; Brewer, Mark; Carro, Joseph; Collins, Sarah; Estrada, Chris; Johnson, Jolyon; Salam, Akash; Wallen, Vera; Warren, Naomi; Smith, Thomas C.; Armstrong, James D.; McGaughey, Steve; Pye, John; Mohanan, Kakkala; Church, Rebecca

    2012-05-01

    Double stars have been systematically observed since William Herschel initiated his program in 1779. In 1803 he reported that, to his surprise, many of the systems he had been observing for a quarter century were gravitationally bound binary stars. In 1830 the first binary orbital solution was obtained, leading eventually to the determination of stellar masses. Double star observations have been a prolific field, with observations and discoveries - often made by students and amateurs - routinely published in a number of specialized journals such as the Journal of Double Star Observations. All published double star observations from Herschel's to the present have been incorporated in the Washington Double Star Catalog. In addition to reviewing the history of visual double stars, we discuss four observational technologies and illustrate these with our own observational results from both California and Hawaii on telescopes ranging from small SCTs to the 2-meter Faulkes Telescope North on Haleakala. Two of these technologies are visual observations aimed primarily at published "hands-on" student science education, and CCD observations of both bright and very faint doubles. The other two are recent technologies that have launched a double star renaissance. These are lucky imaging and speckle interferometry, both of which can use electron-multiplying CCD cameras to allow short (30 ms or less) exposures that are read out at high speed with very low noise. Analysis of thousands of high speed exposures allows normal seeing limitations to be overcome so very close doubles can be accurately measured.

  1. BOOK REVIEW: Observational Cosmology Observational Cosmology

    NASA Astrophysics Data System (ADS)

    Howell, Dale Andrew

    2013-04-01

    Observational Cosmology by Stephen Serjeant fills a niche that was underserved in the textbook market: an up-to-date, thorough cosmology textbook focused on observations, aimed at advanced undergraduates. Not everything about the book is perfect - some subjects get short shrift, in some cases jargon dominates, and there are too few exercises. Still, on the whole, the book is a welcome addition. For decades, the classic textbooks of cosmology have focused on theory. But for every Sunyaev-Zel'dovich effect there is a Butcher-Oemler effect; there are as many cosmological phenomena established by observations, and only explained later by theory, as there were predicted by theory and confirmed by observations. In fact, in the last decade, there has been an explosion of new cosmological findings driven by observations. Some are so new that you won't find them mentioned in books just a few years old. So it is not just refreshing to see a book that reflects the new realities of cosmology, it is vital, if students are to truly stay up on a field that has widened in scope considerably. Observational Cosmology is filled with full-color images, and graphs from the latest experiments. How exciting it is that we live in an era where satellites and large experiments have gathered so much data to reveal astounding details about the origin of the universe and its evolution. To have all the latest data gathered together and explained in one book will be a revelation to students. In fact, at times it was to me. I've picked up modern cosmological knowledge through a patchwork of reading papers, going to colloquia, and serving on grant and telescope allocation panels. To go back and see them explained from square one, and summarized succinctly, filled in quite a few gaps in my own knowledge and corrected a few misconceptions I'd acquired along the way. To make room for all these graphs and observational details, a few things had to be left out. For one, there are few derivations

  2. Geo-neutrino Observation

    SciTech Connect

    Dye, S. T.; Alderman, M.; Batygov, M.; Learned, J. G.; Matsuno, S.; Mahoney, J. M.; Pakvasa, S.; Rosen, M.; Smith, S.; Varner, G.; McDonough, W. F.

    2009-12-17

    Observations of geo-neutrinos measure radiogenic heat production within the earth, providing information on the thermal history and dynamic processes of the mantle. Two detectors currently observe geo-neutrinos from underground locations. Other detection projects in various stages of development include a deep ocean observatory. This paper presents the current status of geo-neutrino observation and describes the scientific capabilities of the deep ocean observatory, with emphasis on geology and neutrino physics.

  3. Héliosismologie: observations.

    NASA Astrophysics Data System (ADS)

    Fossat, E.

    Contents: (1) Introduction. (2) Les observables. (3) Les observations. (4) Paramètres à mesurer. (5) Le problème du temps d'intégration. (6) Les programmes d'observation actuels. (7) A propos de la précision des mesures. (8) Sélection de quelques résultats récents et de problèmes en suspens parmi d'autres. (9) En guise de conclusion provisoire. (10) IRIS status report.

  4. Jupiter System Observer

    NASA Technical Reports Server (NTRS)

    Senske, Dave; Kwok, Johnny

    2008-01-01

    This slide presentation reviews the proposed mission for the Jupiter System Observer. The presentation also includes overviews of the mission timeline, science goals, and spacecraftspecifications for the satellite.

  5. BAA Observers' Workshops: Observing the aurora

    NASA Astrophysics Data System (ADS)

    Gavine, D.

    2004-10-01

    Although auroral and upper-atmosphere research is carried out mainly in polar regions by professional scientists, it is still worthwhile for the amateur to observe this beautiful and sometimes spectacular phenomenon for its own sake. Occasionally, however, the BAA Aurora Section is called upon to supply information on displays to a variety of professional organisations, and so it has become important to receive reports, to log them in a standardised method and to maintain a continuous archive which can be consulted by interested persons. Through the kindness and foresight of the late Dr Michael Gadsden this has been done - all our auroral and noctilucent cloud data from the time of Director James Paton in the 1940s up to the present is preserved in the special Balfour Stewart Archive at the Library of Aberdeen University.

  6. Observations sur les fondements acoustiques et perceptifs de certains procedes du systeme verbo-tonal (Observations on the Acoustic and Perceptual Foundations of Some Processes of the Verbo-Tonal System)

    ERIC Educational Resources Information Center

    Landercy, Albert; Renard, Raymond

    1976-01-01

    This article outlines the bases of the verbo-tonal method of correcting phonetic errors in second language learning, a method based on awareness of the phonological system of the learner's native language and its influence on the phonological system of the target language. (Text is in French.) (CLK)

  7. [Temporal and spatial distribution of shorebirds (Charadriiformes) at San Ignacio Lagoon, Baja California Sur, Mexico].

    PubMed

    Mendoza, Luis Francisco; Carmona, Roberto

    2013-03-01

    Baja California Peninsula has several wetlands that represent important ecosystems for shorebirds. San Ignacio Lagoon is one of these sites, and supports 10% of the total abundance of shorebirds reported in this Peninsula. Since there is few information about this group in this area, we studied spatial and temporal changes in abundance and distribution of shorebirds in San Ignacio Lagoon. For this, we conducted twelve monthly censuses (October 2007-September 2008) on the entire internal perimeter of the lagoon, which we divided into four areas: two at the North and two at the South. We observed a seasonal pattern, with the lowest abundance in May (1 585 birds) and the highest in October (47 410). The most abundant species were Marbled Godwits (Limosa fedoa; 55% of the total records), Western Sandpipers (Calidris mauri; 23%), and Willet (Tringa semipalmata; 10%). All three species were more abundant in autumn; for both, the Marbled Godwit and Willet, we observed their highest numbers in winter and spring, while the Western Sandpiper showed noticeable oscillations, reaching a maximum in early winter (December). In summer, Marbled Godwit and Willet were the only birds present but in lower numbers. Here present the first records of the Pacific Red Knot (Calidris canutus roselaari) in the area. Bird abundance and species richness were influenced seasonally by migration and spatially by sites in the lagoon. The greatest shorebird abundance was in the South area of the lagoon, probably because of better accessibility to food. Our results allowed the inclusion of San Ignacio Lagoon in the Western Hemisphere Shorebirds Reserve Network (WHSRN) as a site of international importance.

  8. Turbulence Heating ObserveR - THOR

    NASA Astrophysics Data System (ADS)

    Retino, Alessandro; Marcucci, Maria FedericaFederica; Vaivads, Andris; Escoubet, C. Philippe; Khotyaintsev, Yuri; Fazakerley, Andrew; Soucek, Jan; Gehler, Martin; Lavraud, Benoit; Vainio, Rami; Valentini, Francesco; Chen, Christopher H. K.; Narita, Yasuhito; Wielders, Arno

    2016-07-01

    Turbulent fluctuations are ubiquitous in astrophysical plasmas and reach up to scales as large as stars, bubbles or clouds blown out by stellar winds, or even entire galaxies. However, most of the irreversible energy dissipation produced by turbulent fluctuations occurs at very small scales, the so-called kinetic scales, where the plasma no longer behaves as a fluid and the properties of individual plasma species (electrons, protons, and other ions) become important. The heating of different plasma species as well as the acceleration of particles to high energies are governed by kinetic processes which determine how the turbulent electromagnetic fluctuations dissipate. Thus, processes at kinetic scales directly affect the large-scale properties of astrophysical plasmas. Turbulence Heating ObserveR (THOR) is the first mission ever flown in space fully dedicated to study plasma turbulent fluctuations and associated energization mechanisms. It will explore the kinetic plasma processes that determine the fundamental behavior of the majority of baryonic matter in the universe. THOR will lead to an understanding of the basic plasma heating and particle acceleration mechanisms, of their effect on different plasma species and of their relative importance in different turbulent regimes. THOR will provide closure of these fundamental questions by making detailed in situ measurements of the closest available dilute and turbulent magnetized plasmas at unprecedented temporal and spatial resolution. THOR focuses on particular regions in space: the pristine solar wind, the Earth's bow shock and interplanetary shocks, and the compressed solar wind regions downstream of shocks. These regions are selected because of their different turbulence properties, and reflect similar astrophysical environments. THOR is a candidate for selection as the next ESA M4 mission. Here we present THOR's science as well as the results of the ongoing mission study, currently undertaken at ESA.

  9. Observing Classroom Practice

    ERIC Educational Resources Information Center

    Danielson, Charlotte

    2012-01-01

    Classroom observation is a crucial aspect of any system of teacher evaluation. No matter how skilled a teacher is in other aspects of teaching--such as careful planning, working well with colleagues, and communicating with parents--if classroom practice is deficient, that individual cannot be considered a good teacher. Classroom observations can…

  10. Crew Earth Observations

    NASA Technical Reports Server (NTRS)

    Runco, Susan

    2009-01-01

    Crew Earth Observations (CEO) takes advantage of the crew in space to observe and photograph natural and human-made changes on Earth. The photographs record the Earth's surface changes over time, along with dynamic events such as storms, floods, fires and volcanic eruptions. These images provide researchers on Earth with key data to better understand the planet.

  11. Observe Your Shadow

    ERIC Educational Resources Information Center

    Rovšek, Barbara

    2016-01-01

    Observe Your Shadow was the title of an observational experiment that was, among others, conducted in the scope of the past year's (2014-2015) first Slovene science competition for elementary school pupils between the ages of 6 and 13. The main reason for establishing a new science competition was popularization of science and its experimental…

  12. Developing Observation Skills

    ERIC Educational Resources Information Center

    Ashbrook, Peggy

    2010-01-01

    We typically know children are learning when they are able to make sense of an object's materials or a situation that was previously a bit mysterious and communicate what they have figured out. But what about observing? One of the process skills listed in the National Science Education Standards (NRC 1996), observation is something students have…

  13. Comet Observations with SIRTF

    NASA Technical Reports Server (NTRS)

    Cruikshank, Dale P.

    2003-01-01

    Comet observations are included in the programs of the Guaranteed Time Observers (GTO) on the Space Infrared Telescope Facility (SIRTF), scheduled to be in space and operational for five years beginning in late 2003. SIRTF is a cryogenic telescope with three basic instruments for imaging, photometry and spectroscopy from 3.6 m to 160 m. All of these capabilities will be used in studies of comets. The intent is to study the infrared radiation (emission) from comets (and dust tails, where relevant) in all stages of evolution, starting with Kuiper Belt objects and Centaurs (thermal emission at 24,70, and 160 m to derive dimensions and albedos). Active comets will be observed spectroscopically and in deep thermal images. Several known or suspected extinct comets will be observed spectroscopically (5-37 m) for information on their surface compositions. There are opportunities for Guest Observers (GO) to propose additional comet work. .

  14. Visual observations over oceans

    NASA Technical Reports Server (NTRS)

    Terry, R. D.

    1979-01-01

    Important factors in locating, identifying, describing, and photographing ocean features from space are presented. On the basis of crew comments and other findings, the following recommendations can be made for Earth observations on Space Shuttle missions: (1) flyover exercises must include observations and photography of both temperate and tropical/subtropical waters; (2) sunglint must be included during some observations of ocean features; (3) imaging remote sensors should be used together with conventional photographic systems to document visual observations; (4) greater consideration must be given to scheduling earth observation targets likely to be obscured by clouds; and (5) an annotated photographic compilation of ocean features can be used as a training aid before the mission and as a reference book during space flight.

  15. GRBs Observed by MAXI

    NASA Astrophysics Data System (ADS)

    Serino, M.; Sakamoto, T.; Yoshida, A.; Kawai, N.; Morii, M.; Sugizaki, M.; Nakahira, S.; Negoro, H.; Mihara, T.; Nishimura, Y.; Ogawa, Y.; Matsuoka, M.

    2013-07-01

    Monitor of All-sky X-ray Image (MAXI) on board International Space Station is capable of observing gamma-ray bursts (GRBs) and sending notices of GRBs or other transient events, using real time connection to the ground. MAXI observed 32 GRBs or short X-ray transients as of the end of September 2012. Among them, eleven events were simultaneously detected by other satellites. The observed rate of the MAXI GRBs is about one event per month. This rate is comparable to a past observation with larger effective area and larger field of view. The fact indicates that MAXI has better sensitivity to observe GRBs because of low background. The distribution of the spectral hardness of MAXI GRBs is similar to the results of a past instrument, which is sensitive to similar energy range.

  16. Observables in effective gravity

    SciTech Connect

    Giddings, Steven B.; Marolf, Donald; Hartle, James B.

    2006-09-15

    We address the construction and interpretation of diffeomorphism-invariant observables in a low-energy effective theory of quantum gravity. The observables we consider are constructed as integrals over the space of coordinates, in analogy to the construction of gauge-invariant observables in Yang-Mills theory via traces. As such, they are explicitly nonlocal. Nevertheless we describe how, in suitable quantum states and in a suitable limit, the familiar physics of local quantum field theory can be recovered from appropriate such observables, which we term ''pseudolocal.'' We consider measurement of pseudolocal observables, and describe how such measurements are limited by both quantum effects and gravitational interactions. These limitations support suggestions that theories of quantum gravity associated with finite regions of spacetime contain far fewer degrees of freedom than do local field theories.

  17. Observing the new Moon

    NASA Astrophysics Data System (ADS)

    Hoffman, Roy E.

    2003-04-01

    The first appearance of the new Moon has been used throughout history and is still used today to determine religious calendars. Many methods for predicting the Moon's appearance have been proposed throughout history and new models are still being developed. All these models have to be tested against observations to test their validity. To this end, ancient and modern astronomers have collected observations of new and old crescent Moons. Here we present the results of 539 observations of the Moon made over several years by many experienced observers in good weather conditions. In addition to determining whether or not the Moon was seen, the times of its first and last appearance were also carefully recorded. The addition of the appearance time means that even an easily visible Moon, recorded when it can barely be seen, may be compared with a visibility criterion. The observational data base greatly expands on previously published reports.

  18. Influence de revetements bioactifs sur les cellules endotheliales: Vers des protheses vasculaires non thrombotiques

    NASA Astrophysics Data System (ADS)

    Fadlallah, Hicham

    Developing vascular prostheses of small diameter to replace vessels closed by atherosclerosis remains a challenge because of the risk of thrombosis. Seeding of endothelial cells, which have antithrombogenic properties, is a promising solution, but we must create surfaces which promote their adhesion and retention to resist shear stresses created by the blood flow on the surface. This master's project aimed at investigating the effect of a plasma polymerized coating rich in primary amines (called LP), with or without elements of the extracellular matrix (Fibronectin (FN) or chondroitin sulphate (CS)) on the endothelial cells and hemocompatibility of polyethylene terephthalate (PET). The adhesion, growth and retention of human umbilical vein endothelial cells (HUVECs) on PET and LP, in the presence and absence of FN or CS, have been studied. In addition, platelet adhesion on different surfaces was evaluated by a perfusion test with whole blood, platelets being previously labeled with rhodamine. Finally a double fluorescent labeling (using Cellview Maroon to mark the HUVECs and CD61 antibody for platelets) was developed to study the retention of endothelial cells, under blood flow and verify their non thrombogenic character. The results obtained show that both the LP coating and the adsorbed FN, strongly increase both the cellular adhesion and growth on PET; however they have no additional effect when the two are combined. They also augment cellular retention to surface, but this remains incomplete. Moreover we observed that the plasma coating (LP) greatly increases the thrombogenicity of the surface, with strong platelet adhesion and activation. This thrombogenicity is extremely reduced when endothelial cells cover the surface, but cell loss under the effect of shear produced by the perfusion creates significant areas of platelet adhesion. The grafting of CS on LP also permits good HUVECs adhesion, growth and retention under shear stress on HUVEC, with no difference

  19. PECVD de composes de silicium sur polymeres: Etude de la premiere phase du depot

    NASA Astrophysics Data System (ADS)

    Dennler, Gilles

    Since their first introduction in the early 90's, transparent barriers against oxygen and/or water vapor permeation through polymers, such as SiO 2, are the object of increasing interest in the food and pharmaceutical packaging industries, and more recently for the encapsulation of organic-based displays. It is now well known that these thin layers possess barrier properties only if they are thicker than a certain critical thickness, dc. For example, dc is around 12 nm in the case of SiO2 on KaptonRTM PI; below this value, the measured "Oxygen Transmission Rate" (OTR, in standard cm3/m2/day/bar) is roughly the same as that of the uncoated polymer. Until now, no detailed research has been carried out to explain this observation, but a hypothesis was proposed in the literature, based on island-like growth structure of the coating for d ≤ dc. According to this hypothesis, the surface energy of the polymeric substrates is so low that the Volmer-Weber (island-coalescence) growth mode occurs. We have aimed to verify this explanation, that is, to study the initial phase of silicon-compound (SiO2 and SiN) growth on four different polymeric substrates, namely polyimide (KaptonRTM PI), polycarbonate (LexanRTM PC), polypropylene (PP), and polyethyleneterephthalate (MylarRTM PET). Three different deposition methods were used, namely reactive evaporation of SiO, radio-frequency (RF) Plasma Enhanced Chemical Vapor Deposition (RF PECVD), and Distributed Electron Cyclotron Resonance (DECR) PECVD. In this latter case, the substrates were placed in three different positions: (i) in the active glow zone, (ii) downstream, and (iii) downstream, but shielded from photon emission (e.g. VUV) from the plasma. Angle-Resolved X-Ray Photoelectron Spectroscopy (ARXPS), Rutherford Backscattering Spectroscopy (RBS), and Scanning Electron Microscopy (SEM), the latter performed after Reactive Ion Etching (RIE) by oxygen plasma, revealed that growth indeed occurs in a Volmer-Weber mode in the

  20. Comportement en fatigue et influence de la temperature sur les proprietes en traction du PLA

    NASA Astrophysics Data System (ADS)

    Menard, Claire

    Current environmental issues reduce the use of materials obtained from fossil resources. The usual plastics therefore tend to be replaced by more green polymers such as polylactic acid (PLA), a bio-based and biodegradable polymer. Knowledge on the properties of this material is essential, especially in terms of fatigue strength and influence of temperature on tensile stiffness and strength. In this study, the PLA samples are submitted to monotonic tensile tests, according to ASTM D638-10, at various temperatures between room temperature (23°C) and the glass transition temperature of the material (55-60°C). The results show a decrease of 30% of the modulus of elasticity and 60% of the tensile strength between these two temperatures. This decrease is mainly due to a significant drop in the mechanical properties beyond 50°C. In addition, tensile fatigue tests were conducted at loads rate between 40 and 80% of tensile strength, at room temperature in order to plot the Wohler curve of PLA. The ruptured specimens were finally observed with a scanning electron microscope (SEM) to analyze the failure mechanisms in fatigue of PLA.

  1. K-Ar ages confirm Pliocene age for oldest Neogene marine strata near Loreto, Baja California Sur, Mexico

    SciTech Connect

    McLean, H.

    1987-05-01

    Beds of pumiceous tuff interbedded with mollusk-rich sedimentary rocks provide new age constraints on the timing of the late Neogene subsidence and marine transgression a few kilometers north of Loreto, Baja California Sur, Mexico. The lower part of the Neogene section consists of approximately 1500 m of early to middle Miocene nonmarine volcanic-derived sandstone, breccia, and porphyritic andesite and dacite lavas, called the Comondu Formation or Comondu Group by previous workers. The Miocene rocks are unconformably overlain by nearly 1000 m of predominantly marine sandstone, siltstone, conglomerate, coquina, and tuff of Pliocene age. This 1000-m section grades upward from unfossiliferous fanglomerate, sandstone, and pelitic red beds that are interpreted to be nonmarine into mollusk-rich marine strata; this sequence indicates that marine transgression occurred within the Pliocene section. Plagioclase and hornblende from three pumiceous tuff beds stratigraphically located near the base, middle, and top of the marine section yield K-Ar ages of 3.2, 1.9, and 1.8 Ma, respectively; these ages are similar to Pliocene ages indicated by reconnaissance studies of ostracods, diatoms, and foraminifers. The diatoms indicate open-ocean waters and the foraminifers indicate outer shelf depth. Ostracods, oysters, pectens, and other fossil bivalves seem to indicate a shallow-water embayment. Lateral distribution of nonmarine and marine facies suggests a paleoenvironment in which alluvial fans fed coarse debris into a series of coastal fan deltas. The Pliocene basin may have been a largely landlocked embayment similar to the modern Bahia Concepcion, located 70 km north of Loreto. Marine and volcanic rocks are assumed to be associated with the opening of the Gulf of California. If this assumption is correct, the beds near Loreto suggest that the opening occurred during the Pliocene.

  2. Transmission Sur Fibres Optiques Dans Un Systeme D'Archivage Et De Communication D'Images Pour Des Applications Medicales

    NASA Astrophysics Data System (ADS)

    Aaron, Gilles; Bonnard, Rene

    1984-03-01

    Dans l'hOpital, le besoin d'un reseau de communication electronique ne cesse de crottre au fur et a mesure de la numerisation des images. Ce reseau local a pour but de relier quelques sources d'images telles la radiologie numerique, la tomodensitometrie, la resonance magnetique nucleaire, l'echographie ultraso-nore etc..., a un systme d'archivage. Des consoles de visualisation interacti-ves peuvent etre utilisees dans les salles d'examens, les bureaux des medecins et les services de soins. Dans un tel systme, trois caracteristiques princi-pales doivent etre prises en compte le debit, la longueur du cable et le nombre de connexions. - Le debit est tr?)s important, en effet, un temps de reponse maxima de quel-ques secondes doit etre garanti pour des images de plusieurs millions d'ele-ments binaires. - La distance entre connexions peut etre de quelques km dans certains grands hopitaux. - Le nombre de connexions au reseau ne depasse jamais quelques dizaines car les sources d'images et les unites de traitement representent des materiels importants, par ailleurs les consoles de visualisation simples peuvent etre groupees en grappe. Toutes ces conditions sont remplies par les transmissions sur fibres optiques. Selon la topologie et la methode d'accNs, deux solutions peuvent etre envisa-gees : - Anneau actif - Etoile active ou passive Enfin, les developpements de Thomson-CSF en composants pour transmissions optiques pour les grands reseaux de tel4distribution nous apportent un support technologique et une production de masse qui diminuera les collts du materiel.

  3. Galileo's Observations of Neptune

    NASA Astrophysics Data System (ADS)

    Standish, E. M.

    2001-11-01

    In 1979, Stillman Drake and Charles Kowal found that the astronomer Galileo actually observed the planet Neptune in the years 1612 and 1613. Galileo's observing notebooks still exist and are preserved in the National Central Library in Florence, Italy. In them, one can see the discovery of the four large moons of Jupiter, and one can follow the subsequent work of Galileo as he improved his telescopes, charted the nightly positions of the satellites, and refined his ability to predict their future configurations. One sees his observing innovations and improving accuracies which seem to reach a crescendo just at the time of his observations of Neptune. Further scrutiny of Galileo's notebooks has revealed other intriguing observations. One is a probable fourth observation of Neptune which has a direct bearing upon present-day ephemerides. There are also observations of two other objects which, to this day, despite some effort, remain unidentified - possibly asteroids, comets, novae, or supernovae. More than of just historical interest, Galileo's work still has important implications for present-day astronomy. The research described in this talk was carried out at the Jet Propulsion Laboratory, California Institute of Technology, under contract with the National Aeronautics and Space Administration.

  4. Catalog of infrared observations

    NASA Technical Reports Server (NTRS)

    Gezari, D. Y.; Schmitz, M.; Mead, J. M.

    1982-01-01

    The infrared astronomical data base and its principal data product, the catalog of Infrared Observations (CIO), comprise a machine readable library of infrared (1 microns to 1000 microns astronomical observations. To date, over 1300 journal articles and 10 major survey catalogs are included in this data base, which contains about 55,000 individual observations of about 10,000 different infrared sources. Of these, some 8,000 sources are identifiable with visible objects, and about 2,000 do not have known visible counterparts.

  5. Catalog of infrared observations

    NASA Astrophysics Data System (ADS)

    Gezari, D. Y.; Schmitz, M.; Mead, J. M.

    1984-05-01

    The infrared astronomical data base and its principal data product, the catalog of Infrared Observations (CIO), comprise a machine readable library of infrared (1 microns to 1000 microns astronomical observations. To date, over 1300 journal articles and 10 major survey catalogs are included in this data base, which contains about 55,000 individual observations of about 10,000 different infrared sources. Of these, some 8,000 sources are identifiable with visible objects, and about 2,000 do not have known visible counterparts.

  6. Coastal dynamics off Cabo Pulmo, Baja California Sur, México

    NASA Astrophysics Data System (ADS)

    Trasviña-Castro, A.; Gonzalez-Rodriguez, E.; Zaitsev, O. V.

    2013-05-01

    Cabo Pulmo is the one of the few coral reefs of the Mexican Pacific. It is located to the north of the Tropic of Cancer (at 23.5° N) and therefore formally in the subtropical region. It is part of the Gulf of California but its location near the tip of the Peninsula pose questions about the exchange of properties with the neighboring Pacific Ocean, some of which will be addressed here. It was declared National Park in 1995. Since then it became a no-take zone and a nature reserve for the preservation of the large variety of species found there. We report results based on meteorological and hydrographic observations as well as current measurements gathered between October 2010 and February 2012. These results include the presence of coastal currents forced by the tide, the wind and remote forcing. We believe the latter are associated, sometimes, to the mesoscale circulation of the entrance to the Gulf of California and, at other times, to coastal jets coming from the interior of the Gulf. We use displacement diagrams to discuss the trends of the residual circulation along the coast. During autumn, winter and even in spring the residual coastal flow is towards the Equator. This is attributed to the influence of the Northwesterly winds that blow over the Gulf of California in these months. It is in summer that the coastal residual circulation exhibits a poleward component being more intense during Southeasterly wind events. Finally, we present evidence of coastal exchange with the Pacific Ocean in the form of an intense jet. This coastal jet flows equatorward past Cabo Pulmo, continues towards the Pacific side of the Peninsula and generates offshore filaments when turning the cape.

  7. Nouvelles Limites sur la Detection Directe de la Matiere Sombre avec l'Experience PICASSO

    NASA Astrophysics Data System (ADS)

    Piro, Marie-Cecile

    Astronomical and cosmological observations strongly suggest the presence of an exotic form of non-relativistic, non-baryonic matter that would represent 26% of the actual energy-matter content of the Universe. This so-called cold dark matter would be composed of Weakly Interactive Massive Particles (WIMP). PICASSO (Project In CAnada to Search for Supersymmetric Objects) aims to detect directly one of the dark matter candidates proposed in the framework of supersymmetric extensions of the standard model : the neutralino. The experiment is installed in the SNOLAB underground laboratory at Sudbury (Ontario) and uses superheated C4F10 droplets detectors, a variant of bubble chamber technique. Phase transitions in the superheated liquids are triggered by 19F recoils caused by the elastic collision with neutralinos and create an acoustic signal which is recorded by piezoelectric sensors. This thesis presents recent progress in PICASSO leading to a substantially increased sensitivity in the search of neutralinos. New fabrication and purification procedures allowed a background reduction of about a factor 10 of the major detectors contamination caused by alpha emitters. Detailed studies allowed to localize these emitters in the detectors. In addition, data analysis efforts were able to improve substantially the discrimination between alpha particle induced events and those created by nuclear recoils. New analysis tools were also developed in order to discriminate between particle induced and non-particle induced events, such as electronic backgrounds and acoustic noise signals. An important new background suppression mechanism at higher temperatures led to the present improved sensitivity of PICASSO at low WIMP masses.

  8. Technique distribuee de gestion de la charge sur le reseau electrique et ring-tree: Un nouveau systeme de communication P2P

    NASA Astrophysics Data System (ADS)

    Ayoub, Simon

    Le reseau de distribution et de transport de l'electricite se modernise dans plusieurs pays dont le Canada. La nouvelle generation de ce reseau que l'on appelle smart grid, permet entre autre l'automatisation de la production, de la distribution et de la gestion de la charge chez les clients. D'un autre cote, des appareils domestiques intelligents munis d'une interface de communication pour des applications du smart grid commencent a apparaitre sur le marche. Ces appareils intelligents pourraient creer une communaute virtuelle pour optimiser leurs consommations d'une facon distribuee. La gestion distribuee de ces charges intelligentes necessite la communication entre un grand nombre d'equipements electriques. Ceci represente un defi important a relever surtout si on ne veut pas augmenter le cout de l'infrastructure et de la maintenance. Lors de cette these deux systemes distincts ont ete concus : un systeme de communication peer-to-peer, appele Ring-Tree, permettant la communication entre un nombre important de noeuds (jusqu'a de l'ordre de grandeur du million) tel que des appareils electriques communicants et une technique distribuee de gestion de la charge sur le reseau electrique. Le systeme de communication Ring-Tree inclut une nouvelle topologie reseau qui n'a jamais ete definie ou exploitee auparavant. Il inclut egalement des algorithmes pour la creation, l'exploitation et la maintenance de ce reseau. Il est suffisamment simple pour etre mis en oeuvre sur des controleurs associes aux dispositifs tels que des chauffe-eaux, chauffage a accumulation, bornes de recharges electriques, etc. Il n'utilise pas un serveur centralise (ou tres peu, seulement lorsqu'un noeud veut rejoindre le reseau). Il offre une solution distribuee qui peut etre mise en oeuvre sans deploiement d'une infrastructure autre que les controleurs sur les dispositifs vises. Finalement, un temps de reponse de quelques secondes pour atteindre 1'ensemble du reseau peut etre obtenu, ce qui est

  9. Effets potentiels d’un modèle rationnel de prescription sur les dépenses nationales en santé

    PubMed Central

    Littman, Jordan; Halil, Roland

    2016-01-01

    Résumé Objectif Estimer les économies que pourrait engendrer la mise en œuvre d’un modèle rationnel de prescription pour des classes de médicaments équivalents sur les plans de l’efficacité, de la toxicité et de la commodité. Conception L’Institut canadien d’information sur la santé a fourni des renseignements sur les 10 principales classes de médicaments en fonction des dépenses annuelles qui leur sont attribuables. Ces classes ont été examinées en vue de leur inclusion potentielle dans l’étude selon qu’il était possible de comparer les médicaments à l’intérieur d’une même classe. Lorsqu’à la suite d’une recherche documentaire, une équivalence a été établie en fonction de l’efficacité, de la toxicité et de la commodité des médicaments, les données annuelles sur les prescriptions ont été recueillies à partir de la base de données du Système national d’information sur l’utilisation des médicaments prescrits. Les économies potentielles de coûts ont ensuite été calculées en comparant les parts de marché actuelles avec les parts potentielles futures de ce marché. Contexte Le Canada. Principaux paramètres à l’étude Les différences estimées dans les dépenses que produirait un modèle rationnel de prescription. Résultats Une équivalence a été établie sur les plans de l’efficacité, de la toxicité et de la commodité dans les classes de statines, d’inhibiteurs de la pompe à protons, d’inhibiteurs de l’enzyme de conversion de l’angiotensine et d’inhibiteurs sélectifs du recaptage de l’angiotensine. Les dépenses annuelles totales dans ces classes se situent à 856 millions $ dans les programmes publics de médicaments et à 1,97 milliard $ environ à l’échelle nationale. Grâce à des prescriptions rationnelles, on estime que les économies annuelles pourraient atteindre 222 millions $ pour les programmes publics et 521 millions $ à l’échelle nationale. Conclusion La

  10. The Earth Observing System

    NASA Astrophysics Data System (ADS)

    Wilson, Stan; Dozier, Jeff

    1991-09-01

    The Earth Observing System (EOS), the centerpiece of NASA's Mission to Planet Earth, is to study the interactions of the atmosphere, land, oceans, and living organisms, using the perspective of space to observe the earth as a global environmental system. To better understand the role of clouds in global change, EOS will measure incoming and emitted radiation at the top of the atmosphere. Then, to study characteristics of the atmosphere that influence radiation transfer between the top of the atmosphere and the surface, EOS wil observe clouds, water vapor and cloud water, aerosols, temperature and humidity, and directional effects. To elucidate the role of anthropogenic greenhouse gas and terrestrial and marine plants as a source or sink for carbon, EOS will observe the biological productivity of lands and oceans. EOS will also study surface properties that affect biological productivity at high resolution spatially and spectrally.

  11. Observing System Simulation Experiments

    NASA Technical Reports Server (NTRS)

    Prive, Nikki

    2015-01-01

    This presentation gives an overview of Observing System Simulation Experiments (OSSEs). The components of an OSSE are described, along with discussion of the process for validating, calibrating, and performing experiments. a.

  12. Motor learning by observing.

    PubMed

    Mattar, Andrew A G; Gribble, Paul L

    2005-04-01

    Learning complex motor behaviors like riding a bicycle or swinging a golf club is based on acquiring neural representations of the mechanical requirements of movement (e.g., coordinating muscle forces to control the club). Here we provide evidence that mechanisms matching observation and action facilitate motor learning. Subjects who observed a video depicting another person learning to reach in a novel mechanical environment (imposed by a robot arm) performed better when later tested in the same environment than subjects who observed similar movements but no learning; moreover, subjects who observed learning of a different environment performed worse. We show that this effect is not based on conscious strategies but instead depends on the implicit engagement of neural systems for movement planning and control. PMID:15820701

  13. Observers and Reality

    NASA Astrophysics Data System (ADS)

    Jaroszkiewicz, George

    The following sections are included: * Introduction * Basic Concepts and Terms * Particles * Questions, Answers, and Laboratories * Observers and Experiments * The Stern-Gerlach Experiment * The DS Experiment * The Monitored DS Experiment * The Contextuality of Space and Time * Acknowledgment * References

  14. Observing earth from Skylab

    NASA Technical Reports Server (NTRS)

    1975-01-01

    Skylab technology and observations of earth resources are discussed. Special attention was given to application of Skylab data to mapmaking, geology/geodesy, water resources, oceanography, meteorology, and geography/ecology.

  15. Mars Observer Press Conference

    NASA Technical Reports Server (NTRS)

    1993-01-01

    Footage shows Bob MacMillin, NASA's Public Information Office, as he introduces the Mars Observer Project Manager, Glen Cunningham. Glen is shown addressing the current status of the Mars Observer communication system, the inability of NASA to establish contact, and the action that is currently being taken to establish contact with the spacecraft. Glen is also seen answering questions from both the audience as well as other NASA Centers.

  16. Points quantiques sur substrat d'indium phosphure: Plate-forme pour des composantes optoelectroniques accordables

    NASA Astrophysics Data System (ADS)

    Allen, Claudine

    InAs/InGaAsP quantum dots were embedded in laser diode structures grown on (100) InP and tunable lasing has been observed between 1.5 mum and 1.7 mum. We first investigated the dynamics of charge carriers and photons in these laser diodes. It was found that the carriers confined in the quantum dots have discrete energy states like those of a bidimensional harmonic oscillator. The interaction between charge carriers and electromagnetic waves was analyzed through the electrical susceptibility. This has confirmed the possibility of wave amplification if the charge carrier population in the quantum dots is inverted, eventually leading to lasing if enough current is injected. Next, we have studied experimentally three different laser diode structures; their spectral properties and their super linear relation between emitted optical power and injected current demonstrate lasing characteristics. The best optoelectronic performance was obtained for the structure with the deepest charge carrier confinement potential and largest density of quantum dots, but an increase of this second parameter doesn't guarantee an improvement of the performance. At room temperature, a laser threshold current density of 1.1 kA/cm 2 and an external quantum differential efficiency of 9.4% have been measured for this laser diode structure as well as a good internal quantum efficiency of 25% approximately. This efficiency decrease from internal to external was attributed to high internal photon losses with a coefficient of 28 cm-1. Typical increase of the threshold current density with temperature was verified with characteristic temperatures between 52 K and 121 K, but this characteristic temperature abnormally increased above 180 K for two of the three laser diode structures. Spectral tuning potential was assessed by studying the effect of temperature and length of the laser diodes on their lasing wavelength. Promising results incited us to set up an external cavity tunable laser based on our

  17. FuzzObserver

    NASA Technical Reports Server (NTRS)

    Howard, Ayanna; Bayard, David

    2006-01-01

    Fuzzy Feature Observation Planner for Small Body Proximity Observations (FuzzObserver) is a developmental computer program, to be used along with other software, for autonomous planning of maneuvers of a spacecraft near an asteroid, comet, or other small astronomical body. Selection of terrain features and estimation of the position of the spacecraft relative to these features is an essential part of such planning. FuzzObserver contributes to the selection and estimation by generating recommendations for spacecraft trajectory adjustments to maintain the spacecraft's ability to observe sufficient terrain features for estimating position. The input to FuzzObserver consists of data from terrain images, including sets of data on features acquired during descent toward, or traversal of, a body of interest. The name of this program reflects its use of fuzzy logic to reason about the terrain features represented by the data and extract corresponding trajectory-adjustment rules. Linguistic fuzzy sets and conditional statements enable fuzzy systems to make decisions based on heuristic rule-based knowledge derived by engineering experts. A major advantage of using fuzzy logic is that it involves simple arithmetic calculations that can be performed rapidly enough to be useful for planning within the short times typically available for spacecraft maneuvers.

  18. Investigation of the role of the BAM complex and SurA chaperone in outer-membrane protein biogenesis and type III secretion system expression in Salmonella.

    PubMed

    Fardini, Yann; Trotereau, Jérôme; Bottreau, Elisabeth; Souchard, Charlène; Velge, Philippe; Virlogeux-Payant, Isabelle

    2009-05-01

    In Escherichia coli, the assembly of outer-membrane proteins (OMP) requires the BAM complex and periplasmic chaperones, such as SurA or DegP. Previous work has suggested a potential link between OMP assembly and expression of the genes encoding type-III secretion systems. In order to test this hypothesis, we studied the role of the different lipoproteins of the BAM complex (i.e. BamB, BamC, BamD and BamE), and the periplasmic chaperones SurA and DegP, in these two phenotypes in Salmonella. Analysis of the corresponding deletion mutants showed that, as previously described with the DeltabamB mutant, BamD, SurA and, to a lesser extent, BamE play a role in outer-membrane biogenesis in Salmonella Enteritidis, while the membrane was not notably disturbed in DeltabamC and DeltadegP mutants. Interestingly, we found that BamD is not essential in Salmonella, unlike its homologues in Escherichia coli and Neisseria gonorrhoeae. In contrast, BamD was the only protein required for full expression of T3SS-1 and flagella, as demonstrated by transcriptional analysis of the genes involved in the biosynthesis of these T3SSs. In line with this finding, bamD mutants showed a reduced secretion of effector proteins by these T3SSs, and a reduced ability to invade HT-29 cells. As DeltasurA and DeltabamE mutants had lower levels of OMPs in their outer membrane, but showed no alteration in T3SS-1 and flagella expression, these results demonstrate the absence of a systematic link between an OMP assembly defect and the downregulation of T3SSs in Salmonella; therefore, this link appears to be related to a more specific mechanism that involves at least BamB and BamD. PMID:19372159

  19. Superposition tridimensionnelle (3-D) sur la base du crâne pour l’évaluation longitudinale des effets de la croissance et du traitement

    PubMed Central

    Cevidanes, Lucia H.S.; Styner, Martin; Proffit, William R.; Ngom, Traduit par Papa Ibrahima

    2010-01-01

    RÉSUMÉ – Pour évaluer les modifications liées à la croissance ou au traitement, il est nécessaire de superposer les céphalogrammes successifs sur une structure stable. En céphalométrie bidimensionnelle (2-D), la base du crâne est souvent utilisée pour les superpositions parce que les changements qu’elle subit après le développement cérébral sont mineurs. Toutefois, sur les céphalogrammes de profil et de face, les points de repère basicraniens sont peu fiables. Dans cet article, nous présentons une nouvelle méthode de superposition tridimensionnelle (3-D) basée sur un enregistrement entièrement automatisé des intensités de voxels, au niveau de la surface de la base du crâne. Le progiciel utilisé permet l’évaluation quantitative des modifications qui apparaissent dans le temps, grâce au calcul de la distance euclidienne entre les surfaces du modèle tridimensionnel. Il permet également l’appréciation visuelle de l’emplacement et de l’importance des modifications au niveau des maxillaires, grâce à une surimpression graphique. Les modifications sont visualisées par comparaison à des tables de correspondance de couleur. On peut ainsi réaliser une étude détaillée des modes d’adaptation chez les patients dont la croissance et/ou le traitement ont provoqué des modifications squelettiques cliniquement significatives. PMID:19954732

  20. Recent observed climate change over the Arabian Peninsula

    NASA Astrophysics Data System (ADS)

    Alsarmi, Said; Washington, Richard

    2011-06-01

    We have examined trends in temperature and precipitation parameters for the Arabian Peninsula (AP) during the last 2 to 3 decades. The data set has been carefully quality controlled and checked for homogeneity. Although of low density (21 stations) and relatively short time period, a clear picture of climate change in the region has emerged. The general pattern of the AP mean annual temperature trend is one of warming, with 14 of 21 stations show statistically significant warming at 0.05 level and most at 0.001 level and only one (Seeb) showing statistically significant cooling. The highest statistically significant mean annual warming trends are found in Oman (Sur = 1.03°C decade-1) and Emirates (Dubai = 0.81°C decade-1). The season of maximum warming in mean temperature is March to April. The highest monthly mean temperature trend in the AP occurs in Sur in May (1.47°C decade-1). There is a broad statistically significant increase in mean annual maximum temperature in AP in 12 out of 21 stations, with the highest trends in central and eastern/southeastern AP. Only SW AP and the Gulf of Oman do not show warming. The highest monthly maximum temperature trend in the AP occurs in Bahrain in March (2.27°C decade-1). The second highest significant warming trends are reported in Doha in February (1.54°C decade-1). For minimum temperature, 16 out of 21 stations show statistically significant warming trends, with the highest annual trends observed in the Emirates (Dubai = 1.24°C decade-1), northwest Oman (Sohar = 1.17°C decade-1) and Qatar (Doha = 1.13°C decade-1). The highest monthly minimum temperature warming rate occurred in October. Both Dubai and Kuwait reported the highest significant rate of 2.00°C decade-1. The general mean annual diurnal temperature range trend is negative in the AP, with six out of 21 stations show statistically significant negative trends while three stations show statistically significant positive trends. Trends in mean annual

  1. Observations of Deep Flow along the Central California Coast

    NASA Astrophysics Data System (ADS)

    Collins, Curtis; Margolina, Tetyana; Rago, Thomas

    2016-04-01

    A number of programs have collected observations of deep currents and water properties over the continental shelf off Central California during the past three decades. Here we summarize the results of these measurements. The oldest data set included bimonthly observations off Point Sur (33° 20'N) from April 1988 to April 1991 using an acoustically tracked dropsonde and a NBIS Mk III CTD. The poleward flow observed above 1000 m was weaker at depth but generally dominated the flow pattern. Deep (˜1000 m) currents were also observed off California from August 1994 to September 2009 using current meters and RAFOS floats. Current meter data were collected at nine locations for time periods ranging from two months to 76 months. A total of 144 months of float data were collected. Analysis of current meter data included histograms, progressive vector diagrams, stick plots, kinetic energy and rotary spectra, stick plots, means and standard deviations. Float data were analyzed using trajectories and calculating means, standard deviations, and diffusivities. For current meter data, semidiurnal tidal energy dominated the kinetic energy spectrum, anticyclonic rotary motion exceeded cyclonic motion, kinetic energy was typically an order of magnitude greater than for diurnal frequencies, and kinetic energy decreased about an order of magnitude as depth increased by 1000 m. Mean speed for current meter (float) data was 6.1 (4.0) cm s‑1 and alongshore variability exceeded across shore variability. Two floats were entrained in mesoscale eddies, one cyclonic and the other anticyclonic; the eddies moved westward at a speed of about one cm s‑1. Seasonal variability along the continental slope was marked by late summer or early fall warming; eddy kinetic energy was minimum in February, 3 cm2 s‑2.

  2. D'Eichthal and Urbain's "Lettres sur la race noire et la race blanche": race, gender, and reconciliation after slave emancipation.

    PubMed

    Andrews, Naomi J

    2011-01-01

    This article is a close reading of Gustave D'Eichthal and Ishmayl Urbain's Lettres sur la race noire et la race blanche (1839), written during the decade prior to the "second" French emancipation in 1848. The article argues that the hierarchical gendering of race described in the letters is reflective of metropolitan concerns about potential for social disorder accompanying slave emancipation in the French colonies. In arguing for social reconciliation through interracial marriage and its offspring, the symbolically charged figure of the mulatto, the authors deployed gendered and familial language to describe a stable post-emancipation society.

  3. Scénarios dynamiques d'une fibre dopée erbium fonctionnant sur deux longueurs d'onde

    NASA Astrophysics Data System (ADS)

    Bérisson, W.; Besnard, P.; Ginovart, F.; Le Boudecl, P.; Sanchez, F.; Stéphan, G. M.

    2002-06-01

    Nous montrons la sensibilité à l'anisotropie de pompe des diagrammes de bifurcation d'une fibre dopée erbium fonctionnant sur deux longueurs d'onde. Un très bon accord entre les diagrammes de bifurcation expérimentaux et ceux obtenus théoriquement a été obtenu. De nouveaux types de bistabilités (3T-chaos et IT-chaos) sont mis en évidence pour ces systèmes.

  4. Evaluation du niveau de connaissance des patients sur la gestion du traitement par les antis vitamines K dans le service de cardiologie de Ouagadougou

    PubMed Central

    Samadoulougou, André; Temoua Naibe, Dangwé; Mandi, Germain; Yameogo, Relwendé Aristide; Kabore, Elisé; Millogo, Georges; Yameogo, Nobila Valentin; Kologo, Jonas Koudougou; Thiam/Tall, Anna; Toguyeni, Boubacar Jean Yves; Zabsonre, Patrice

    2014-01-01

    Introduction Les antivitamines K (AVK), traitement anticoagulant oral le plus largement prescrit, posent un réel problème de santé publique du fait de leur risque iatrogène. L'objectif de cette étude était de préciser le niveau de connaissance des patients sur la gestion de leur traitement par les AVK. Méthodes Il s'est agi d'une enquête transversale descriptive réalisée au CHU-Yalgado Ouédraogo, sur une période de 03 mois : du 1er mars au 31 mai 2012. Un questionnaire a été administré aux patients bénéficiant d'un traitement AVK depuis au moins un mois. Résultats Soixante-dix patients ont été inclus dans l'étude dont 30 hommes. L'âge moyen était de 49 ans ± 16 ans. Les cardiopathies et la maladie thromboembolique veineuse justifiant l'institution du traitement AVK étaient retrouvées respectivement dans 58,6% et 41,4% des cas. Le nom de l'AVK et la raison exacte du traitement étaient connus respectivement dans 91,4% et 67,1% des cas. Plus de la moitié des patients (68,6%) savaient que les AVK rendaient le sang plus fluide. Quarante-six patients (65,7%) citaient l'INR comme examen biologique de surveillance du traitement et seulement 28 patients (40%) connaissaient les valeurs cibles. La majorité des patients ne connaissait pas les risques encourus en cas de surdosage (72,8%) et de sous-dosage (71,4%). Une automédication par anti-inflammatoire non stéroïdien était signalée par 18 patients (25,7%). Les choux (74,3%) et la laitue (62,9%), aliments à consommer avec modération, étaient les plus cités. Conclusion Les connaissances des patients sur la gestion des AVK étaient fragmentaires et insuffisantes pour assurer la sécurité et l'efficacité du traitement. La création d'un programme d'éducation thérapeutique sur les AVK s'avère alors nécessaire. PMID:25870741

  5. Etudes sur la gravitation: Theories alternatives en 2+1 et 3+1 dimensions

    NASA Astrophysics Data System (ADS)

    Edery, Ariel

    to study a 2 + 1 dimensional model. However, in 2 + 1 dimensions, the analog to Einstein gravity is trivial. The space-time outside sources is flat and particles at rest do not interact. The odd dimensional space-time allows one to include a gravitational Chern-Simons term called a topological mass term because it gives mass to the graviton. In article three and four, we consider localized mass and spin sources in the full non-linear theory. We obtain solutions for both of Vuorio's sectors. In article 3 we demonstrate that delta function sources, while allowed in the linearized theory are not consistent with the full non-linear field equations. In article four, we consider how to embed point sources in Vuorio's cosmological sector and discuss the metric solution for the case when observers are near and far away from the source. (Abstract shortened by UMI.)

  6. The pioneer woman's view of migraine: Elizabeth Garrett Anderson's thesis "Sur la migraine".

    PubMed

    Wilkinson, M; Isler, H

    1999-01-01

    This is a presentation of a doctoral thesis of 1870. The author was English but the thesis and the examinations were in French. Elizabeth Garrett Anderson, usually referred to as E.G.A., was the first woman in Britain to obtain the title of M.D., but not the first in Europe. Nadeshda Prokofevna Suslova, a Russian, received her M.D. in 1867 in Zurich, the most liberal university at that time, soon to be flooded by female students from Russia. E.G.A. had been applying to the few possible European universities but she settled for Paris after the Empress Eugenie had decided that she should be accepted there. This meant that she could succeed without having to be a Paris resident, just by writing a thesis and passing a series of examinations presided over by Paul Broca. This was important as she was already conducting private and dispensary practice, and could not find a locum (she insisted on a woman). E.G.A. had suffered many setbacks, for being a woman, as such being unacceptable in dissection rooms and operating theatres, and generally in a professional career where women were unheard of. She was finally permitted to receive her medical diploma from the Worshipful Society of Apothecaries of London. She wrote about her thesis: "I have chosen Headache as its subject. I had to find a subject which could be well studied without post-mortem observations, of which I can have but very few in either private or dispensary practice; and I wished also to take a large subject, one that demanded some insight into the harmony that exists between the main physiological functions." Marcia Wilkinson (M.W.), who worked in the Elizabeth Garrett Anderson Hospital in London for 35 years, heard there of E.G.A.'s thesis on migraine and sent for it from Paris. In 1966 she translated it into English from the original French, being interested both in the subject and in the person of this resolute and lucid woman. When H. Isler found the French thesis in the British Library he intended to

  7. Uranian Equinoctial Observations

    NASA Astrophysics Data System (ADS)

    Bauer, J. M.; Hammel, H. B.; Young, L. A.; Olkin, C. B.; Goguen, J. D.; Hicks, M.; Schmidt, B.; Lainey, V.; Chanover, N. J.; Miller, C.; Hibbitts, C. A.; Baines, K. H.; Arlot, J.; Fitzsimmons, A.; Buratti, B. J.

    2008-12-01

    In December of 2007, the planet Uranus passed through its northern hemisphere spring equinox. The northernmost latitudes of the planet and regular satellites were exposed to sunlight for the first time in 42 years. Unique circumstances during the equinoctial event also concerning the viewing geometries of the rings and satellites provided rare opportunities to determine the physical nature of these elements of the Uranian system and to study the short-term and evolutionary effects of seasonal insolation in the outer solar system. Furthermore, the approaching perspective afforded opportunities to characterize details of surfaces that had not been viewable, even by Voyager 2, since the advent of modern instrumentation. We present preliminary results from these observations made over several nights during the 2006, 2007, and 2008 observing semesters. Our imaging using the Palomar adaptive optics system on the observatory's 200- inch telescope has been used to obtain high-resolution images. These observations have provided constraints on the planet's atmospheric dynamics and structure by monitoring the increasing storm activity and changing large-scale features in the atmosphere, such as the shifting polar collar, and sampling the vertical structure from multiple planetary occultations. These same images also provide unique photometric information regarding the ring-system particles by viewing the system from its dark side, accessible only during the 2007 season. Spectral and spectro-photometric observations of the newly exposed surfaces of the major satellites have also been obtained from the IRTF, the SOAR telescope, and Palomar 200-inch, including observations of some mutual event phenomena. Acknowledgements: These results are based in part on observations obtained at the Hale Telescope, Palomar Observatory, as part of a collaborative agreement between Caltech, JPL and Cornell University. Some observations were also obtained at the Infrared Telescope Facility, which

  8. East Asian observations

    NASA Astrophysics Data System (ADS)

    Stephenson, F. R.

    East Asian observations are of established importance in Applied Historical Astronomy. The earliest astronomical records from this part of the world (China, Japan and Korea) originate from China. These observations, mainly of lunar eclipses, are recorded on oracle bones from the period ca. 1300 - 1050 BC. Virtually all later Chinese and other East Asian astronomical records now exist only in printed copies. The earliest surviving series of solar eclipse observations from any part of the world is contained in the Chunqiu (722 - 481 BC), a chronicle of the Chinese state of Lu. However, not until after 200 BC, with the establishment of a stable empire in China, do detailed astronomical records survive. These are mainly contained in specially compiled astrological treatises in the official dynastic histories. Such records, following the traditional style, extend down to the start of the present century. All classes of phenomena visible to the unaided eye are represented: solar and lunar eclipses, lunar and planetary movements among the constellations, comets, novae and supernovae, meteors, sunspots and the aurora borealis. Parallel, but independent series of observations are recorded in Japanese and Korean history, especially after about AD 800. Sources of Japanese records tend to be more diverse than their Chinese and Korean counterparts, but fortunately Kanda Shigeru (1935) and Ohsaki Shyoji (1994) have made extensive compilations of Japanese astronomical observations down to the 1860s. Throughout East Asia, dates were expressed in terms of a luni-solar calendar.

  9. Heisenberg's observability principle

    NASA Astrophysics Data System (ADS)

    Wolff, Johanna

    2014-02-01

    Werner Heisenberg's 1925 paper 'Quantum-theoretical re-interpretation of kinematic and mechanical relations' marks the beginning of quantum mechanics. Heisenberg famously claims that the paper is based on the idea that the new quantum mechanics should be 'founded exclusively upon relationships between quantities which in principle are observable'. My paper is an attempt to understand this observability principle, and to see whether its employment is philosophically defensible. Against interpretations of 'observability' along empiricist or positivist lines I argue that such readings are philosophically unsatisfying. Moreover, a careful comparison of Heisenberg's reinterpretation of classical kinematics with Einstein's argument against absolute simultaneity reveals that the positivist reading does not fit with Heisenberg's strategy in the paper. Instead the appeal to observability should be understood as a specific criticism of the causal inefficacy of orbital electron motion in Bohr's atomic model. I conclude that the tacit philosophical principle behind Heisenberg's argument is not a positivistic connection between observability and meaning, but the idea that a theory should not contain causally idle wheels.

  10. ALMA Observations of TNOs

    NASA Astrophysics Data System (ADS)

    Butler, Bryan J.; Brown, Michael E.

    2016-10-01

    Some of the most fundamental properties of TNOs are still quite poorly constrained, including diameter and density. Observations at long thermal wavelengths, in the millimeter and submillimeter, hold promise for determining these quantities, at least for the largest of these bodies (and notably for those with companions). Knowing this information can then yield clues as to the formation mechanism of these bodies, allowing us to distinguish between pairwise accretion and other formation scenarios.We have used the Atacama Large Millimeter/Submillimeter Array (ALMA) to observe Orcus, Quaoar, Salacia, and 2002 UX25 at wavelengths of 1.3 and 0.8 mm, in order to constrain the sizes of these bodies. We have also used ALMA to make astrometric observations of the Eris-Dysnomia system, in an attempt to measure the wobble of Eris and hence accurately determine its density. Dysnomia should also be directly detectable in those data, separate from Eris (ALMA has sufficient resolution in the configuration in which the observations were made). Results from these observations will be presented and discussed.

  11. Observed Barium Emission Rates

    NASA Technical Reports Server (NTRS)

    Stenbaek-Nielsen, H. C.; Wescott, E. M.; Hallinan, T. J.

    1993-01-01

    The barium releases from the CRRES satellite have provided an opportunity for verifying theoretically calculated barium ion and neutral emission rates. Spectra of the five Caribbean releases in the summer of 1991 were taken with a spectrograph on board a U.S. Air Force jet aircraft. Because the line of sight release densities are not known, only relative rates could be obtained. The observed relative rates agree well with the theoretically calculated rates and, together with other observations, confirm the earlier detailed theoretical emission rates. The calculated emission rates can thus with good accuracy be used with photometric observations. It has been postulated that charge exchange between neutral barium and oxygen ions represents a significant source for ionization. If so. it should be associated with emissions at 4957.15 A and 5013.00 A, but these emissions were not detected.

  12. Ultraviolet observations of comets

    NASA Technical Reports Server (NTRS)

    Code, A. D.; Houck, T. E.; Lillie, C. F.

    1972-01-01

    The first observations of a comet in the vacuum ultraviolet were obtained on January 14, 1970, when OAO-2 recorded the spectrum of the bright comet Tago-Sato-Kosaka (1969g). The observations revealed, among other things, the predicted extensive hydrogen Lyman alpha halo. OAO-2 continued to collect spectrophotometric measurements of this comet throughout January of that year; a photograph of the nucleus in Lyman alpha revealed finer scale structures. In February of 1970, the bright comet Bennet (1969i) became favorable for space observations. On the basis of the OAO discovery, OGO-V made several measurements of comet Bennet with low spatial resolution photometers. Comet Enke was detected by OGO in January of 1971 at a large heliocentric distance from its Lyman alpha emission.

  13. Multiscale ground aurora observations

    NASA Astrophysics Data System (ADS)

    Kozelov, Boris

    Aurora is the most impressive phenomenon that initially motivates people's interest in the study of near-Earth space. Now auroral observations provide unique information about the processes occurring in the magnetosphere-ionosphere plasma: this is the only type of observations that gives detailed two-dimensional spatial distribution with sufficient temporal resolution. Fractal power-law distributions that are typical for aurora indicate the passing transients in near-Earth plasma. Spatio-temporal dynamics of active auroral forms on the night side is showing signs of turbulence and self-organized criticality at huge range of scales. Pulsing auroral forms are usually associated with the wave-particle interaction. The report describes the current state of the ground-based optical observations of aurorae at different scales and methods of analysis of their results.

  14. Observed climate change hotspots

    NASA Astrophysics Data System (ADS)

    Turco, M.; Palazzi, E.; Hardenberg, J.; Provenzale, A.

    2015-05-01

    We quantify climate change hotspots from observations, taking into account the differences in precipitation and temperature statistics (mean, variability, and extremes) between 1981-2010 and 1951-1980. Areas in the Amazon, the Sahel, tropical West Africa, Indonesia, and central eastern Asia emerge as primary observed hotspots. The main contributing factors are the global increase in mean temperatures, the intensification of extreme hot-season occurrence in low-latitude regions and the decrease of precipitation over central Africa. Temperature and precipitation variability have been substantially stable over the past decades, with only a few areas showing significant changes against the background climate variability. The regions identified from the observations are remarkably similar to those defined from projections of global climate models under a "business-as-usual" scenario, indicating that climate change hotspots are robust and persistent over time. These results provide a useful background to develop global policy decisions on adaptation and mitigation priorities over near-time horizons.

  15. Astrometric observations of triton

    NASA Astrophysics Data System (ADS)

    Qiao, R. C.; Yan, Y. R.; Shen, K. X.; Dourneau, G.; Xi, X. J.; Cheng, X.; Wang, S. H.; Tang, Z. H.; Liu, J. R.

    2007-04-01

    Astrometric positions of the Neptunian Satellite Triton are given for the opposition of Neptune for the years 1996, 2003, 2005 and 2006. The 943 observed positions were obtained at the Cassegrain focus of a 156-cm reflector. In our reduction, the up-to-date catalogue of stars UCAC2 was chosen to ensure a proper astrometric calibration. Our observed positions are compared to theoretical positions provided from JPL and IMCCE ephemerides. The observed minus calculated residuals have s.d. values of the order of 0.04 arcsec. The data are available in electronic form as Supplementary Material to the online version of the paper on Blackwell Synergy, at the CDS via anonymous FTP to http://cdsarc.u-strasbg.fr or via http://cdsweb.u-strasbg.fr/Abstract.html. E-mail: rcqiao@ntsc.ac.cn

  16. Observe Your Shadow

    NASA Astrophysics Data System (ADS)

    Rovšek, Barbara

    2016-04-01

    Observe Your Shadow was the title of an observational experiment that was, among others, conducted in the scope of the past year's (2014-2015) first Slovene science competition for elementary school pupils between the ages of 6 and 13. The main reason for establishing a new science competition was popularization of science and its experimental methods, particularly among elementary school students. Elementary school teachers are not generally specialists in science, but rather have (and should have) extremely wide scopes of interests and competencies. By providing them with ideas and instructions for science experiments, we aim to enrich regular school lessons. In the first year alone, the competition took place in over half of Slovene elementary schools, with a total of 9000 participating students. In this paper we shall report about pupils' responses to tasks related to one of the experiments, namely, observation of their shadows on a sunny day.

  17. Observations from Sarmizegetusa Sanctuary

    NASA Astrophysics Data System (ADS)

    Barbosu, M.

    2000 years ago, Sarmizegetusa Regia was the capital of ancient Dacia (today: Romania). It is known that the Dacian high priests used the Sanctuary of Sarmizegetusa not only for religious ceremonies, but also for astronomical observations. After having completed geodesic measurements, we analyzed the architecture of the sanctuary with its main points, directions and circles. We discuss here what kind of astronomical observations could have been made with the scientific knowledge of that time. The final section of this work is dedicated to the remarkable resemblance between Sarmizegztusa and Stonehenge.

  18. Observations of interstellar zinc

    NASA Technical Reports Server (NTRS)

    Jura, M.; York, D.

    1981-01-01

    The International Ultraviolet Explorer observations of interstellar zinc toward 10 stars are examined. It is found that zinc is at most only slightly depleted in the interstellar medium; its abundance may serve as a tracer of the true metallicity in the gas. The local interstellar medium has abundances that apparently are homogeneous to within a factor of two, when integrated over paths of about 500 pc, and this result is important for understanding the history of nucleosynthesis in the solar neighborhood. The intrinsic errors in detecting weak interstellar lines are analyzed and suggestions are made as to how this error limit may be lowered to 5 mA per target observation.

  19. The SETI observational plan

    NASA Technical Reports Server (NTRS)

    Berman, A. L.

    1980-01-01

    The SETI (Search for Extraterrestrial Intelligence) Project's primary thrust is to search the microwave region of the spectrum for signals of extraterrestrial intelligent origin. The project will search a well defined volume of search parameter space using existing antennae and a sophisticated data acquisition and analysis system. Two major components are included, the target survey, which will observe at very high sensitivity all attractive stellar candidates within 75 light years of the Sun, and the sky survey, which will observe the entire celestial sphere at a lower sensitivity.

  20. Observations of UU Cancri

    NASA Astrophysics Data System (ADS)

    Kalv, P.; Oja, T.; Harvig, V.

    2007-07-01

    We present UBVR photometric observations of the 96-day binary system UU Cancri (K4 III) obtained in 1972-1994. A relatively large scatter in the orbital light curves turned out to be intrinsic with a modulating cycle lasting at least 8000 days. Using all available archived photographic and visual observations covering nearly 100 years, we find the orbital period of the system to be constant. This fact, together with the pattern of the colour curves, makes the existence of a powerful accretion disk in the system improbable.

  1. Conceptualization of groundwater flow of a coastal arid aquifer using isotopic and chemical tools: La Paz, Baja California Sur, Mexico

    NASA Astrophysics Data System (ADS)

    Tamez-Melendez, Carol; Hernández-Antonio, Arturo; Mahlknecht, Jürgen

    2016-04-01

    Groundwater from the La Paz coastal aquifer in Baja California Sur, Mexico, is the main source of drinking water for the local population. Due to its proximity to the coast, sea water intrusion is the main factor of salinization of groundwater. Other geochemical processes also affect the quality of the aquifer threating its vulnerability. Forty-seven samples were analyzed for ion chemistry and isotopes. A hierarchical cluster analysis was performed for a better interpretation resulting in three main groups and proved for geographical correspondence. Deuterium and d18O ranged from -82 to -52.1 and from -11.6 to -7 permil, respectively, showing that the main recharge originates in the Sierra el Novillo, flowing toward SE-NW direction and in accordance to deuterium excess (d) high evaporation effects (d>10‰) are mostly in the middle portion of the study area and in El Centenario due to high kinetic isotope fractioning related to elevated temperatures. Hydrogeochemistry analyses demonstrated salinization mainly due to sea water intrusion and in second instance due water-rock interaction, where enrichment of Na+ (ranges from 35.7 to 1089 mg/L-1) was present in some samples probably due to weathering of silicates and/or cation exchange in soils with Ca2+ (27.7 to 658 mg/L-1) at clay-surfaces. High concentrations of NO3-2 (ranges from 1.4 to 48.8 mg/L-1), Cl- (ranges from 54.4 to 2960 mg/L-1) and Na+ show that anthropogenic input is mainly coming from an agricultural area (El Centenario-Chametla) where heavy groundwater extractions are made for irrigational purposes, lowering the groundwater table up to 10 m and consequently promoting upconing and salinity concentrations (NaCl). Carbon-13 and radiocarbon ranged from -12.3 to -9.1‰ and from 29.5 to 100.4 pmC, respectively. Distribution of ages (up to ~5000 years) indicates two flow trends (E-W and SE-NW).

  2. Sedimentologic Assessment of a Makran Tsunami Depsoit in Sur Lagoon Using High- Resolution Particle Size Distributions (PSDs) and Cluster Analysis

    NASA Astrophysics Data System (ADS)

    Reinhardt, E. G.; Donato, S. V.; Boyce, J. I.; Pilarczyk, J. E.

    2008-12-01

    The Makran subduction zone, which conveys the Arabian plate beneath Eurasia, has a poorly understood potential to generate tsunamis that would strike Oman, Iran, Pakistan, and India. The 1945 Makran earthquake (M 8.1), which resulted from a rupture 100-150 km long, caused a tsunami that reached heights of 5-15 m and killed an estimated 3,000 people on the coast of what is now Pakistan. The possibility of a full- length Makran rupture, approx. 750 km long, remains untested. The arid coastlines of the northern Arabian Sea (including parts of Oman, Iran, Pakistan and India) have had little attention regarding paleo-tsunami research. They lack the main environments where tsumani deposits have been found on temperate shores: tidal marshes, peatlands, and coastal lakes. Instead they offer sandy lagoons and salt flats where tsunami-laid sand sheets can be removed by wind, confused with the deposits of wadi sheet floods, and obliterated by burrowing crabs. Recent research has shown that a shell bed in Oman, likely from the 1945 tsunami (Sur Lagoon - Donato et al., 2008), contained distinctive molluscan assemblages and taphonomy, showing promise as a tsunami indicator for these arid settings. However, the large size of the molluscs is problematic in cores with small sample sizes, as the taphonomic data might not be representative enough to determine a tsunami origin without the use of additional proxies. Further characterization of the shell bed in Oman utilized high-resolution (cm scale) PSDs and Q-mode cluster analysis to identify the tsunami bed in cores (n=8). Results showed that the shell bed was more poorly sorted, and heterogeneous than the background lagoonal sediments. The tsunami bed thickness correlated generally with the thickness of the shell-bed, however cluster analysis of the particle size distributions (PSDs) extended the unit several centimeters above or below the shell-bed in some cores. The use of the full PSD (94 size classes) better characterized the

  3. Mise à jour sur le nouveau vaccin 9-valent pour la prévention du virus du papillome humain

    PubMed Central

    Yang, David Yi; Bracken, Keyna

    2016-01-01

    Résumé Objectif Informer les médecins de famille quant à l’efficacité, à l’innocuité, aux effets sur la santé publique et à la rentabilité du vaccin 9-valent contre le virus du papillome humain (VPH). Qualité des données Des articles pertinents publiés dans PubMed jusqu’en mai 2015 ont été examinés et analysés. La plupart des données citées sont de niveau I (essais randomisés et contrôlés et méta-analyses) ou de niveau II (études transversales, cas-témoins et épidémiologiques). Des rapports et recommandations du gouvernement sont aussi cités en référence. Message principal Le vaccin 9-valent contre le VPH, qui offre une protection contre les types 6, 11, 16, 18, 31, 33, 45, 52 et 58 du VPH, est sûr et efficace et réduira encore plus l’incidence des infections à VPH, de même que les cas de cancer lié au VPH. Il peut également protéger indirectement les personnes non immunisées par l’entremise du phénomène d’immunité collective. Un programme d’immunisation efficace peut prévenir la plupart des cancers du col de l’utérus. Les analyses montrent que la rentabilité du vaccin 9-valent chez les femmes est comparable à celle du vaccin quadrivalent original contre le VPH (qui protège contre les types 6, 11, 16 et 18 du VPH) en usage à l’heure actuelle. Toutefois, il faut investiguer plus en profondeur l’utilité d’immuniser les garçons avec le vaccin 9-valent contre le VPH. Conclusion en plus d’être sûr, le vaccin 9-valent protège mieux contre le VPH que le vaccin quadrivalent. Une analyse coûtefficacité en favorise l’emploi, du moins chez les adolescentes. Ainsi, les médecins devraient recommander le vaccin 9-valent à leurs patients plutôt que le vaccin quadrivalent contre le VPH.

  4. Renaud Paulian et le programme du CNRS sur les hautes montagnes à Madagascar: étage vs domaine

    PubMed Central

    Guillaumet, Jean-Louis; Betsch, Jean-Marie; Callmander, Martin W.

    2011-01-01

    Résumé Le programme intitulé « Étude des écosystémes montagnards dans la région malgache» (RCP 225/CNRS; responsable: Recteur Renaud Paulian) avait pour ambition de dégager leurs caractères généraux, l'origine des éléments constitutifs et de tester la validité d'un Domaine malgache des Hautes Montagnes proposé par Humbert dès 1951. De 1970 à 1973, trois campagnes (Andringitra; Chaînes anosyennes et Ankaratra; Itremo, Ibity et Marojejy) ont permis une caractérisation écologique des milieux particuliers ainsi que des analyses de systématique sur certains taxa connus pour leur intérêt biogéographique. La succession altitudinale des formations végétales, définies par des critères physionomiques et structuraux, est précisée par massif. Le dernier étage caractérisé par le fourré éricoïde et ses groupements associés ne correspond pas à l'Étage des Hautes Montagnes de l'Est africain. Des groupes de la faune (invertébrés hexapodes: Collemboles et Dermaptères) indiquent une disjonction entre les massifs du Nord (Tsaratanana, Marojejy), ceux du Centre et du Sud; des éléments de la flore (Pandanaceae, Araliaceae, Asteraceae) sont en cours d'analyse dans le même sens. Le Domaine des Hautes montagnes à Madagascar est une réalité écologique mais ne peut être défini floristiquement; chaque massif montagneux est une entité phytogéographique d'étages de végétation interdépendants inclus dans les différents Sous-Domaines du Centre. Les groupes peu mobiles de la faune indiquent globalement une dépendance trophique et bioclimatique (effet tampon du climat intraforestier) vis-à-vis des étages de végétation, mais peuvent réagir à des microclimats locaux par des décalages à leurs limites. PMID:21731422

  5. Speech of italian ambassador

    ScienceCinema

    None

    2016-07-12

    L'ambassadeur italien (nom?)fait un discours sur l'aspect de la recherche au Cern, une organisation internationale qui a comme but la connaissance dans sa forme la plus pure et libre d'un intérêt planétaire. Il remet un prix au DG C.Rubbia qui lui remercie en français

  6. Observability of complex systems

    PubMed Central

    Liu, Yang-Yu; Slotine, Jean-Jacques; Barabási, Albert-László

    2013-01-01

    A quantitative description of a complex system is inherently limited by our ability to estimate the system’s internal state from experimentally accessible outputs. Although the simultaneous measurement of all internal variables, like all metabolite concentrations in a cell, offers a complete description of a system’s state, in practice experimental access is limited to only a subset of variables, or sensors. A system is called observable if we can reconstruct the system’s complete internal state from its outputs. Here, we adopt a graphical approach derived from the dynamical laws that govern a system to determine the sensors that are necessary to reconstruct the full internal state of a complex system. We apply this approach to biochemical reaction systems, finding that the identified sensors are not only necessary but also sufficient for observability. The developed approach can also identify the optimal sensors for target or partial observability, helping us reconstruct selected state variables from appropriately chosen outputs, a prerequisite for optimal biomarker design. Given the fundamental role observability plays in complex systems, these results offer avenues to systematically explore the dynamics of a wide range of natural, technological and socioeconomic systems. PMID:23359701

  7. An Observing Session

    NASA Astrophysics Data System (ADS)

    Argyle, Bob; Argyle, R. W.

    In this chapter I describe a typical observing session with the 8-in. (20-cm) Thorrowgood refractor at the Institute of Astronomy in Cambridge. The telescope belongs to the Royal Astronomical Society but is on permanent loan to the Cambridge University Astronomical Society and has been on its present site since 1930 (Fig. 24.1).

  8. Climate Observations from Space

    NASA Astrophysics Data System (ADS)

    Briggs, Stephen

    2016-07-01

    The latest Global Climate Observing System (GCOS) Status Report on global climate observations, delivered to the UNFCCC COP21 in November 2016, showed how satellite data are critical for observations relating to climate. Of the 50 Essential Climate Variables (ECVs) identified by GCOS as necessary for understanding climate change, about half are derived only from satellite data while half of the remainder have a significant input from satellites. Hence data from Earth observing satellite systems are now a fundamental requirement for understanding the climate system and for managing the consequences of climate change. Following the Paris Agreement of COP21 this need is only greater. Not only will satellites have to continue to provide data for modelling and predicting climate change but also for a much wider range of actions relating to climate. These include better information on loss and damage, resilience, improved adaptation to change, and on mitigation including information on greenhouse gas emissions. In addition there is an emerging need for indicators of the risks associated with future climate change which need to be better quantified, allowing policy makers both to understand what decisions need to be taken, and to see the consequences of their actions. The presentation will set out some of the ways in which satellite data are important in all aspects of understanding, managing and predicting climate change and how they may be used to support future decisions by those responsible for policy related to managing climate change and its consequences.

  9. On Observing the Weather

    ERIC Educational Resources Information Center

    Crane, Peter

    2004-01-01

    Rain, sun, snow, sleet, wind... the weather affects everyone in some way every day, and observing weather is a terrific activity to attune children to the natural world. It is also a great way for children to practice skills in gathering and recording information and to learn how to use simple tools in a standardized fashion. What better way to…

  10. Jupiter System Observer

    NASA Technical Reports Server (NTRS)

    Senske, Dave; Prockter, Louise

    2008-01-01

    This slide presentation reviews the scientific philosophy that is guiding the planning behind the Jupiter System Observer (JSO). The JSO would be a long-term platform for studying Jupiter and the complete Jovian system. The goal is to advance the understanding of the fundamental processes of planetary systems, their formation and evolution.

  11. Skylab 4 crew observations

    NASA Technical Reports Server (NTRS)

    Gibson, E. G.

    1977-01-01

    Comments on food, exercise, scheduling, medical training, the effect of fluid shift, and vestibular phenomena are briefly reported. A ballistocardiographic effect of around 60 beats per minute was observed several times for the whole Skylab cluster. Also experienced were light flashes that were well correlated with the South Atlantic anomaly.

  12. Beyond Casual Observing

    NASA Astrophysics Data System (ADS)

    Ang, R. J. Y.

    2009-03-01

    Amateur astronomers can go beyond casual observing and contribute to real scientific research and astronomy education. The evolutionary stages of an astronomer is discussed, from stargazing as a pastime to taking up a formal degree in astronomy and advancement of Astronomy as a fielf of study.

  13. SWIFT Observations AGN

    NASA Technical Reports Server (NTRS)

    Mushotzky, Richard

    2008-01-01

    I will present results from the x-ray and optical follow-up observations of the Swift Burst Alert Telescope (BAT) Active Galactic Nuclei (AGN) survey. I will discuss the nature of obscuration in these objects, the relationship to optical properties and the change of properties with luminosity and galaxy type.

  14. The Mars Observer database

    NASA Technical Reports Server (NTRS)

    Albee, Arden L.

    1988-01-01

    Mars Observer will study the surface, atmosphere, and climate of Mars in a systematic way over an entire Martian year. The observations of the surface will provide a database that will be invaluable to the planning of a future Mars sample return mission. Mars Observer is planned for a September 1992 launch from the Space Shuttle, using an upper-stage. After the one year transit the spacecraft is injected into orbit about Mars and the orbit adjusted to a near-circular, sun-synchronous low-altitude, polar orbit. During the Martian year in this mapping orbit the instruments gather both geoscience data and climatological data by repetitive global mapping. The scientific objectives of the mission are to: (1) determine the global elemental and mineralogical character of the surface material; (2) define globally the topography and gravitational field; (3) establish the nature of the magnetic field; (4) determine the time and space distribution, abundance, sources, and sinks of volatile material and dust over a seasonal cycle; and (5) explore the structure and aspects of the circulation of the atmosphere. The science investigations and instruments for Mars Observer have been chosen with these objectives in mind. These instruments, the principal investigator or team leader and the objectives are discussed.

  15. Observability of quarks

    SciTech Connect

    Bjorken, J.D.

    1985-12-01

    Even if stable hadrons with fractional charge do not exist, most of the criteria of observability used for ordinary elementary particles apply in principle to quarks as well. This is especially true in a simplified world containing only hadrons made of top quarks and gluons. In the real world containing light quarks, essential complications do occur, but most of the conclusions survive.

  16. COMPTEL solar flare observations

    NASA Technical Reports Server (NTRS)

    Ryan, J. M.; Aarts, H.; Bennett, K.; Debrunner, H.; Devries, C.; Denherder, J. W.; Eymann, G.; Forrest, D. J.; Diehl, R.; Hermsen, W.

    1992-01-01

    COMPTEL as part of a solar target of opportunity campaign observed the sun during the period of high solar activity from 7-15 Jun. 1991. Major flares were observed on 9 and 11 Jun. Although both flares were large GOES events (greater than or = X10), they were not extraordinary in terms of gamma-ray emission. Only the decay phase of the 15 Jun. flare was observed by COMPTEL. We report the preliminary analysis of data from these flares, including the first spectroscopic measurement of solar flare neutrons. The deuterium formation line at 2.223 MeV was present in both events and for at least the 9 Jun. event, was comparable to the flux in the nuclear line region of 4-8 MeV, consistent with Solar-Maximum Mission (SSM) Observations. A clear neutron signal was present in the flare of 9 Jun. with the spectrum extending up to 80 MeV and consistent in time with the emission of gamma-rays, confirming the utility of COMPTEL in measuring the solar neutron flux at low energies. The neutron flux below 100 MeV appears to be lower than that of the 3 Jun. 1982 flare by more than an order of magnitude. The neutron signal of the 11 Jun. event is under study. Severe dead time effects resulting from the intense thermal x-rays require significant corrections to the measured flux which increase the magnitude of the associated systematic uncertainties.

  17. Tensions entre rationalité technique et intérêts politiques : l’exemple de la mise en œuvre de la Loi sur les agences de développement de réseaux locaux de services de santé et de services sociaux au Québec

    PubMed Central

    Contandriopoulos, D.; Hudon, Raymond; Martin, Elisabeth; Thompson, Daniel

    2013-01-01

    Sommaire L’objet de cet article est constitué par les processus décisionnels entourant la mise en œuvre de la Loi sur les agences de développement de réseaux locaux de services de santé et de services sociaux (Loi 25). Nous entendons mettre en lumière les stratégies des groupes ou institutions de diverses natures qui ont fait valoir leurs préférences et ont tenté, avec un succès inégal, d’influencer les décisions relatives à cette réforme majeure de la structure du système de santé québécois. Au plan théorique, nous nous appuyons principalement sur les modèles d’analyse du lobbying qui, depuis les travaux fondateurs de Milbrath (1960, 1963), présentent cette pratique comme un processus fondamental d’échange d’information. Selon les données colligées dans les retranscriptions d’entrevues, les stratégies observées correspondent effectivement aux caractéristiques constitutives du lobbying et, dans quelques situations, à celles du patronage. La combinaison de ces divers éléments révèle que la mise en œuvre de la Loi 25 s’avère être avant tout un processus proprement politique. Ainsi, furent relégués au second plan les arguments techniques qui composaient initialement les objectifs de la Loi. PMID:23509412

  18. L'endométriose périnéale profonde sur cicatrice d’épisiotomie: à propos d'un cas rare

    PubMed Central

    Laadioui, Meriem; Alaoui, Fdili; Jayi, Sofia; Bouguern, Hakima; Chaara, Hikmat; Melhouf, Moulay Aabdelilah

    2013-01-01

    Parmi les localisations rares de l'endométriose sur cicatrice, celle du périnée demeure exceptionnelle, l'origine en est souvent iatrogène (épisiotomie). Nous rapportons le cas d'une patiente présentant une douleur cyclique, au niveau de la cicatrice d’épisiotomie. Avec à l'examen clinique une masse de 3,5 cm de grand diamètre au niveau de la cicatrice d’épisiotomie. L’écho périnéale a objectivé une image hypoéchgène hétérogène non vascularisée en regard de la cicatrice d’épisiotomie faisant 3,23/1cm. L'excision de la lésion a été réalisée et l’étude anatomopathologique a confirmé le diagnostic d'endométriose. Les suites postopératoires étaient simples avec un recul de 3 mois sans récidive de la douleur ni de la masse. A travers notre cas et une revue de la littérature, nous insistons sur les la nécessité du diagnostic clinique et d'une prise en charge précoce en vue d'améliorer le pronostic de cette entité rare. PMID:24778749

  19. Etude de l'influence de la temperature et de l'humidite sur les proprietes mecaniques en traction des fibres de chanvre et de coco

    NASA Astrophysics Data System (ADS)

    Ho Thi, Thu Nga

    L'objectif de cette etude fut d'etablir l'effet de l'humidite et de la temperature sur la resistance en traction et le module elastique des fibres de chanvre et de coco. Deux etudes ont ete realisees afin d'atteindre cet objectif. La premiere vise l'absorption de l'humidite dans ces fibres en exposition dans l'air (de 0%RH a 80%RH) ainsi que l'absorption de l'eau dans ces fibres immergees dans l'eau aux differentes temperatures. La deuxieme consiste a mesurer la resistance en traction et le module elastique de ces fibres sous differentes conditions d'humidite et de temperature. En basant sur les resultats experimentaux obtenus, les methodes semi empiriques et de reseaux de neurones ont ete utilisees pour but de predire les proprietes en traction (resistance et module d'elasticite) des fibres de chanvre et de coco sous l'influence de l'humidite et de la temperature.

  20. Un essai contrôlé randomisé: effet du port de chaussures à talons hauts sur le squelette appendiculaire inferieur

    PubMed Central

    Koussihouèdé, Fifamè Eudia Nadège; Falola, Jean-Marie; Fousseni, El-Mansour Barres

    2015-01-01

    Introduction Véritable attribut de la féminité, le port de chaussures à talons est devenu une exigence professionnelle dans certaines structures des pays en développement comme le Bénin. L'objectif de ce travail est de déterminer les effets spécifiques du port de chaussures à talons hauts sur le squelette appendiculaire inférieur. Méthodes Des examens radiographiques de face et de profil de la cheville et du genou ont été effectués sur 122 femmes volontaires, âgées en moyenne de 25,09 ± 1,34 ans et ayant les genu varum qui ont participé à cette étude. Résultats Les résultats ont indiqué une augmentation significative de l’écart inter malléolaire, de l’écart inter condylien, de l'angle antérieur du pied et de l'angle fémoro-patellaire. Une diminution significative de l'angle postérieur du pied a été constatée. Conclusion Le port de chaussures à talons hauts est l'une des causes de la gonarthrose, des troubles des articulations de la cheville et du pied. PMID:26113922

  1. Mesure des stades de developpement du sapin baumier (Abies balsamea [L.] Mill.) par teledetection des maxima locaux sur images a tres haute resolution

    NASA Astrophysics Data System (ADS)

    Demers, Alain

    L'objectif principal de cette these est d'identifier les parametres cles pour lier le developpement morphologique de la cime du sapin baumier (Abies balsamea [L.] Mill.) aux patrons de reflectance qu'elle genere sur une image aerienne a haute resolution. La quantite et la distribution spatiale des aiguilles dans le sapin dependent de la structure des branches. Un mecanisme de ramification particulier (la reiteration) ressort comme le parametre cle pour lier l'augmentation de la biomasse foliaire et la forme de la branche. Les reiterats forment des agglomerats de feuillage qui engendrent des inegalites dans les patrons de reflectance de la cime. La reflectance est plus elevee ou il y a une forte concentration de reiterats (maximum local). On demontre que le developpement du sapin baumier se mesure au moyen de l'analyse des maxima locaux de la cime sur une image. La biomasse de l'arbre se mesure par la teledetection et l'analyse des patrons de reflectance de la cime, c'est-a-dire la mesure du niveau de reiteration par le decompte des maxima locaux de la cime. Cette etude demontre qu'il est possible de proceder a l'inventaire du volume de bois d'un peuplement par la teledetection de l'architecture des arbres.

  2. Que nous apprennent les petits frères et sœurs sur les signes précoces d’autisme?1

    PubMed Central

    Rogers, Sally J.

    2010-01-01

    L’objectif de cette revue est de présenter une synthèse des réponses que l’on peut actuellement apporter à la question de savoir quelles sont les premières caractéristiques comportementales qui prédisent le développement de l’autisme. L’article se centre sur 5 points : la présence de Troubles du Spectre Autistique (TSA) dans des groupes de frères et sœurs puînés d’enfants déjà diagnostiqués, les patterns et caractéristiques du développement moteur, les patterns et caractéristiques du développement social et émotionnel, les patterns et caractéristiques de la communication intentionnelle verbale et non verbale, et les patterns qui marquent le début de comportements pathognomoniques de TSA. La discussion porte sur les aspects inattendus des résultats et les pistes de recherche nouvelles qu’ils peuvent engendrer. PMID:20890377

  3. Quaternary structure of K[ssubscript ATP] channel SUR2A nucleotide binding domains resolved by synchrotron radiation X-ray scattering

    SciTech Connect

    Park, Sungjo; Terzic, Andre

    2010-05-25

    Heterodimeric nucleotide binding domains NBD1/NBD2 distinguish the ATP-binding cassette protein SUR2A, a recognized regulatory subunit of cardiac ATP-sensitive K{sup +} (K{sub ATP}) channels. The tandem function of these core domains ensures metabolism-dependent gating of the Kir6.2 channel pore, yet their structural arrangement has not been resolved. Here, purified monodisperse and interference-free recombinant particles were subjected to synchrotron radiation small-angle X-ray scattering (SAXS) in solution. Intensity function analysis of SAXS profiles resolved NBD1 and NBD2 as octamers. Implemented by ab initio simulated annealing, shape determination prioritized an oblong envelope wrapping NBD1 and NBD2 with respective dimensions of 168 x 80 x 37 {angstrom}{sup 3} and 175 x 81 x 37 {angstrom}{sup 3} based on symmetry constraints, validated by atomic force microscopy. Docking crystal structure homology models against SAXS data reconstructed the NBD ensemble surrounding an inner cleft suitable for Kir6.2 insertion. Human heart disease-associated mutations introduced in silico verified the criticality of the mapped protein-protein interface. The resolved quaternary structure delineates thereby a macromolecular arrangement of K{sub ATP} channel SUR2A regulatory domains.

  4. Developpement et validation d'un outil base sur l'acoustique geometrique pour le diagnostic du bruit de nacelle

    NASA Astrophysics Data System (ADS)

    Minard, Benoit

    De nos jours, la problématique du bruit généré par les avions est devenue un point de développement important dans le domaine de l'aéronautique. C'est ainsi que de nombreuses études sont faites dans le domaine et une première approche consiste à modéliser de façon numérique ce bruit de manière à réduire de façon conséquente les coûts lors de la conception. C'est dans ce contexte qu'un motoriste a demandé à l'université de Sherbrooke, et plus particulièrement au groupe d'acoustique de l'Université de Sherbrooke (GAUS), de développer un outil de calcul de la propagation des ondes acoustiques dans les nacelles mais aussi pour l'étude des effets d'installation. Cet outil de prédiction leur permet de réaliser des études afin d'optimiser les traitements acoustiques (« liners »), la géométrie de ces nacelles pour des études portant sur l'intérieur de la nacelle et des études de positionnement des moteurs et de design pour les effets d'installation. L'objectif de ce projet de maîtrise était donc de poursuivre le travail réalisé par [gousset, 2011] sur l'utilisation d'une méthode de lancer de rayons pour l'étude des effets d'installation des moteurs d'avion. L'amélioration du code, sa rapidité, sa fiabilité et sa généralité étaient les objectifs principaux. Le code peut être utilisé avec des traitements acoustiques de surfaces («liners») et peut prendre en compte le phénomène de la diffraction par les arêtes et enfin peut être utilisé pour réaliser des études dans des environnements complexes tels que les nacelles d'avion. Le code développé fonctionne en 3D et procéde en 3 étapes : (1) Calcul des faisceaux initiaux (division d'une sphère, demi-sphère, maillage des surfaces de la géométrie) (2) Propagation des faisceaux dans l'environnement d'étude : calcul de toutes les caractéristiques des rayons convergents (amplitude, phase, nombre de réflexions, ...) (3) Reconstruction du champ de pression en un ou

  5. Observations of Exoplanet Atmospheres

    NASA Astrophysics Data System (ADS)

    Crossfield, Ian J. M.

    2015-10-01

    Detailed characterization of an extrasolar planet's atmosphere provides the best hope for distinguishing the makeup of its outer layers, and the only hope for understanding the interplay between initial composition, chemistry, dynamics and circulation, and disequilibrium processes. In recent years, some areas have seen rapid progress, while developments in others have come more slowly and/or have been hotly contested. This article gives an observer's perspective on the current understanding of extrasolar planet atmospheres prior to the considerable advances expected from the next generation of observing facilities. Atmospheric processes of both transiting and directly imaged planets are discussed, including molecular and atomic abundances, cloud properties, thermal structure, and planetary energy budgets. In the future we can expect a continuing and accelerating stream of new discoveries, which will fuel the ongoing exoplanet revolution for many years to come.

  6. Observational astrochemistry: recent results.

    PubMed

    Irvine, W M

    1989-01-01

    More than 80 molecular species have now been observed by astronomers in the dense interstellar clouds where stars and planets form or in the envelopes expelled by evolved stars. Elemental constituents of these compounds include all of the "biogenic" elements, hydrogen, carbon, nitrogen, oxygen, sulfur, and (most recently) phosphorus. In addition, silicon is found in several molecules, and a series of metal halides have recently been detected in the outflowing envelope of a nearby carbon star. Additions to the list of known interstellar molecules since the last COSPAR meeting are discussed individually. Recent measurements of the hydrogen isotopic fractionation for the cyclic molecule C3H2 are described; values up to 10,000 times the cosmic deuterium-to-hydrogen ratio are found. Knowledge of the chemical reservoirs for the major volatile elements and a comparison between observed molecular abundances and theoretical models are both discussed.

  7. IRAS observations of comets

    NASA Technical Reports Server (NTRS)

    Walker, R. G.; Matson, D. L.; Veeder, G. J.

    1986-01-01

    The moderate spatial resolution and high sensitivity of the Infrared Astronomical Satellite (IRAS), which surveyed the celestial sphere during 1983 at wavelengths of 12, 25, 60, and 100 microns, were particularly well suited to detecting extended thermal emission from cometary dust. Sources with infrared color temperatures characteristic of solar system bodies, and at the ephemerides position of known comets were selected for analysis by the IRAS Asteroid Data Analysis System (ADAS). The data base is now available for use by researchers. This paper describes the development of the data base, details its entries, and presents a statistical analysis of its contents. The IRAS survey contains multiple observations of many periodic comets. A brief description and analysis is given of the observed infrared and derived physical properties for several comets of special interest.

  8. Awareness as observational heterarchy

    PubMed Central

    Sonoda, Kohei; Kodama, Kentaro; Gunji, Yukio-Pegio

    2013-01-01

    Libet et al. (1983) revealed that brain activity precedes conscious intention. For convenience in this study, we divide brain activity into two parts: a conscious field (CF) and an unconscious field (UF). Most studies have assumed a comparator mechanism or an illusion of CF and discuss the difference of prediction and postdiction. We propose that problems to be discussed here are a twisted sense of agency between CF and UF, and another definitions of prediction and postdiction in a mediation process for the twist. This study specifically examines the definitions throughout an observational heterarchy model based on internal measurement. The nature of agency must be emergence that involves observational heterarchy. Consequently, awareness involves processes having duality in the sense that it is always open to the world (postdiction) and that it also maintains self robustly (prediction). PMID:24101912

  9. Gamma Ray Bursts - Observations

    NASA Technical Reports Server (NTRS)

    Gehrels, N.; Cannizzo, J. K.

    2010-01-01

    We are in an exciting period of discovery for gamma-ray bursts. The Swift observatory is detecting 100 bursts per year, providing arcsecond localizations and sensitive observations of the prompt and afterglow emission. The Fermi observatory is observing 250 bursts per year with its medium-energy GRB instrument and about 10 bursts per year with its high-energy LAT instrument. In addition, rapid-response telescopes on the ground are providing new capabilities to study optical emission during the prompt phase and spectral signatures of the host galaxies. The combined data set is enabling great advances in our understanding of GRBs including afterglow physics, short burst origin, and high energy emission.

  10. Other groundbased observations

    NASA Technical Reports Server (NTRS)

    Duvall, Thomas L., Jr.

    1995-01-01

    Ground-based solar observational programs are discussed. The Birmingham (U.K.) solar oscillation network (BiSON) program, the Crimean (Ukraine) low degree program, the Stanford (California) low degree program, the Tenerife (Spain) group program, the South Pole program, the Mount Wilson (California) program, the international research on the interior of the sun (IRIS) network program, the high-l helioseismometer instrument, the ground luminosity oscillations imager (LOI) program, and the Taiwanese oscillation network (TON) program, are outlined.

  11. Safety Observations Achieve Results

    2000-01-16

    The SOAR web application provides a multi-checklist capability where focused observations can be created to address risk-likely work environments, tasks, etc. The SOAR web application has numerous reports to sort the data by key word, multiple factors (i.e., location, team, behavior, checklist, work environment, etc.), and the highest frequency of behaviors and error-likely predecessors, etc. Other performance indicators are also provided.

  12. Southern hemisphere observations

    NASA Astrophysics Data System (ADS)

    Orchiston, Wayne

    Because of insurmountable problems associated with absolute dating, the non-literate cultures of the Southern Hemisphere can contribute little to Applied Historical Astronomy, although Maori traditions document a possible supernova dating to the period 1000-1770 AD. In contrast, the abundant nineteenth century solar, planetary, cometary and stellar observational data provided by Southern Hemisphere professional and amateur observatories can serve as an invaluable mine of information for present-day astronomers seeking to incorporate historical data in their investigations.

  13. Observations on Melkersson's syndrome

    PubMed Central

    Scott, George A.

    1968-01-01

    The findings in nine cases of Melkersson's syndrome are presented. It is suggested that this condition is less uncommon than is generally realized. A careful personal and family history should be taken in all cases of Bell's palsy, and the tongue examined, if this syndrome is to be recognized. Observations are made on the possible aetiology and on treatment. ImagesFig. 1Fig. 2 PMID:5665744

  14. Satellite observations of ethylene

    NASA Astrophysics Data System (ADS)

    Dolan, W.; Payne, V.; Kulawik, S. S.; Bowman, K. W.

    2015-12-01

    Ethylene (C2H4) is a trace gas commonly associated with boreal fire plumes and the petrochemical industry. It has a short lifetime (~1-2 days) in the troposphere due to its reaction with OH. Chemical destruction of ethylene in the atmosphere leads to the production of ozone precursors such as carbon monoxide (CO) and formaldehyde. The Tropospheric Emission Spectrometer (TES) is a Fourier Transform Spectrometer aboard the Aura satellite that measures thermal infrared radiances with high spectral resolution. Trace gas products retrieved routinely from TES spectra include O3, CO, H2O, HDO, CH4, NH3, HCOOH, CH3OH, with OCS and PAN to be included in the next data release. The TES spectra also includes a wealth of untapped information about other trace gasses including ethylene. Ethylene was first observed in TES spectra by Alvarado et al. (2011), though it has yet to be developed into an operational product. Our study focuses on the detection and initial quantitative estimates of ethylene in TES special observations taken in support of the 2008 ARCTAS mission. Initial observations of HCN in the spectra may provide a way to distinguish between fire plume and petrochemical derived ethylene. Results indicate a correlation between ethylene and CO in fresh fire plumes but not in older plumes, consistent with the gas's short lifetime. The approach adopted here to detect ethylene in the TES 2008 ARCTAS special observations can easily be expanded to larger datasets, including those from other thermal infrared sounders as well as to other trace gases.

  15. Observations of interstellar zinc

    NASA Technical Reports Server (NTRS)

    York, D. G.; Jura, M.

    1982-01-01

    IUE observations toward 10 stars have shown that zinc is not depleted in the interstellar medium by more than a factor of two, suggesting that its abundance may serve as a tracer of the true metallicity in the gas. A result pertinent to the history of nucleosynthesis in the solar neighborhood is that the local interstellar medium has abundances that appear to be homogeneous to within a factor of two, when integrated over paths of about 500 pc.

  16. The Spatial Standard Observer

    NASA Technical Reports Server (NTRS)

    Watson, Andrew B.; Ahumada, Albert J, Jr.

    2006-01-01

    The spatial standard observer is a computational model that provides a measure of the visibility of a target in a uniform background image or of the visual discriminability of two images. Standard observers have long been used in science and industry to quantify the discriminability of colors. Color standard observers address the spectral characteristics of visual stimuli, while the spatial standard observer (SSO), as its name indicates, addresses spatial characteristics. The SSO is based on a model of human vision. The SSO was developed in a process that included evaluation of a number of earlier mathematical models that address optical, physiological, and psychophysical aspects of spatial characteristics of human visual perception. Elements of the prior models are incorporated into the SSO, which is formulated as a compromise between accuracy and simplicity. The SSO operates on a digitized monochrome still image or on a pair of such images. The SSO consists of three submodels that operate sequentially on the input image(s): 1. A contrast model, which converts an input monochrome image to a luminance contrast image, wherein luminance values are expressed as excursions from, and normalized to, a mean; 2. A contrast-sensitivity-filter model that includes an oblique-effect filter (which accounts for the decline in contrast sensitivity at oblique viewing angles); and 3. A spatial summation model, in which responses are spatially pooled by raising each pixel to the power beta, adding the results, and raising the sum to the 1/b power. In this model, b=2.9 was found to be a suitable value. The net effect of the SSO is to compute a numerical measure of the perceptual strength of the single image, or of the visible difference (denoted the perceptual distance) between two images. The unit of a measure used in the SSO is the just noticeable difference (JND), which is a standard measure of perceptual discriminability. A target that is just visible has a measure of 1 JND.

  17. Observations of Surfzone Albedo

    NASA Astrophysics Data System (ADS)

    Sinnett, G.; Feddersen, F.

    2014-12-01

    The surfzone environment (where waves break) contains several unique and previously unconsidered processes that affect the heat budget. Entering short-wave radiation is a dominant term in both shelf and surfzone heat budgets. In contrast to the shelf, however, depth limited wave breaking in the surfzone generates spray, whitewater and suspended sediments, elevating the surface albedo (ratio of reflected to incident short-wave radiation). Elevated albedo reduces the level of solar short-wave radiation entering the water, potentially resulting in less heating. Additionally, surfzone water quality is often impacted by fecal bacteria contamination. As bacteria mortality is related to short-wave solar radiation, elevated surfzone albedo could reduce pathogen mortality, impacting human health. Albedo in the open ocean has been frequently studied and parameterizations often consider solar zenith angle, wind speed and ocean chlorophyll concentration, producing albedo values typically near 0.06. However, surfzone albedo observations have been extremely sparse, yet show depth limited wave breaking may increase the albedo by nearly a factor of 10 up to 0.5. Here, we present findings from a field study at the Scripps Institution of Oceanography pier to observe the affect of waves on surfzone albedo. Concurrent measurements were taken with a four-way radiometer (to measure both downwelling and upwelling short-wave and long wave radiation) mounted above the surfzone. A co-located GoPro camera was used to relate visual aspects of the surfzone to measured reflectance, and wave height and period were observed with a bottom mounted pressure sensor in 5 m water depth just outside the surfzone. Wind speed and direction were observed on the pier 10 m above the water surface. Here, we will examine the surfzone albedo dependence on surfzone parameters, such as wave height.

  18. The Earth Observing System

    NASA Technical Reports Server (NTRS)

    Shaffer, Lisa Robock

    1992-01-01

    The restructuring of the NASA Earth Observing System (EOS), designed to provide comprehensive long term observations from space of changes occurring on the Earth from natural and human causes in order to have a sound scientific basis for policy decisions on protection of the future, is reported. In response to several factors, the original program approved in the fiscal year 1991 budget was restructured and somewhat reduced in scope. The resulting program uses three different sized launch vehicles to put six different spacecraft in orbit in the first phase, followed by two replacement launches for each of five of the six satellites to maintain a long term observing capability to meet the needs of global climate change research and other science objectives. The EOS system, including the space observatories, the data and information system, and the interdisciplinary global change research effort, are approved and proceeding. Elements of EOS are already in place, such as the research investigations and initial data system capabilities. The flights of precursor satellite and Shuttle missions, the ongoing data analysis, and the evolutionary enhancements to the integrated Earth science data management capabilities are all important building blocks to the full EOS program.

  19. NICER observation of magnetars

    NASA Astrophysics Data System (ADS)

    Enoto, Teruaki; Kaspi, Victoria M.; Arzoumanian, Zaven

    2016-04-01

    The Neutron Star Interior Composition ExploreR (NICER) is a NASA Explorer Misson of Opportunity as an attached payload aboard the International Space Station (ISS), launch in August 2016. The NICER is planned to study the interior composition and structure within neutron stars via high precise measurement of their stellar mass and radius, also to investigate dynamic and energetic behaviors of their activities. This mission will enable pulsar rotation-resolved spectroscopy in the 0.2--12 keV energy band with large collection area (about twice of the XMM-Newton observatory for soft X-ray timing), precise time-tagging resolution (~200 nsec, 25 times better than RXTE), and high sensitivity (about 2e-14 erg/s/cm2 in the 0.5--10 keV, 5-sigma for 10 ksec exposure). As one of prime goals of the mission, we will describe the science planning of the NICER magnetar observations. The NICER is expected to provide monitoring of fainter magnetar sources which cannot be performed by Swift due to its little collective area. Deep observations of quiescent magnetars and high-B radio pulsars can be also performed with the NICER to study their spectral similarity as a key to investigate the connection between these two sub-classes. Finally, ToO programs are suitable to follow-up the magnate outburst relaxation down to much fainter flux level. We will introduce the NICER strategy of the magnetar observation.

  20. Individual Colorimetric Observer Model

    PubMed Central

    Asano, Yuta; Fairchild, Mark D.; Blondé, Laurent

    2016-01-01

    This study proposes a vision model for individual colorimetric observers. The proposed model can be beneficial in many color-critical applications such as color grading and soft proofing to assess ranges of color matches instead of a single average match. We extended the CIE 2006 physiological observer by adding eight additional physiological parameters to model individual color-normal observers. These eight parameters control lens pigment density, macular pigment density, optical densities of L-, M-, and S-cone photopigments, and λmax shifts of L-, M-, and S-cone photopigments. By identifying the variability of each physiological parameter, the model can simulate color matching functions among color-normal populations using Monte Carlo simulation. The variabilities of the eight parameters were identified through two steps. In the first step, extensive reviews of past studies were performed for each of the eight physiological parameters. In the second step, the obtained variabilities were scaled to fit a color matching dataset. The model was validated using three different datasets: traditional color matching, applied color matching, and Rayleigh matches. PMID:26862905

  1. Enhanced ocean observational capability

    SciTech Connect

    Volpe, A M; Esser, B K

    2000-01-10

    Coastal oceans are vital to world health and sustenance. Technology that enables new observations has always been the driver of discovery in ocean sciences. In this context, we describe the first at sea deployment and operation of an inductively coupled plasma mass spectrometer (ICPMS) for continuous measurement of trace elements in seawater. The purpose of these experiments was to demonstrate that an ICPMS could be operated in a corrosive and high vibration environment with no degradation in performance. Significant advances occurred this past year due to ship time provided by Scripps Institution of Oceanography (UCSD), as well as that funded through this project. Evaluation at sea involved performance testing and characterization of several real-time seawater analysis modes. We show that mass spectrometers can rapidly, precisely and accurately determine ultratrace metal concentrations in seawater, thus allowing high-resolution mapping of large areas of surface seawater. This analytical capability represents a significant advance toward real-time observation and understanding of water mass chemistry in dynamic coastal environments. In addition, a joint LLNL-SIO workshop was convened to define and design new technologies for ocean observation. Finally, collaborative efforts were initiated with atmospheric scientists at LLNL to identify realistic coastal ocean and river simulation models to support real-time analysis and modeling of hazardous material releases in coastal waterways.

  2. Victoire sur les Maths.

    ERIC Educational Resources Information Center

    Tahta, Dick

    1993-01-01

    Presents two case studies from a book by Lusiane Weyl-Kailey in which she addresses the learning problems of 14-year-old boys from either a psychoanalytic perspective or a mathematical perspective, depending upon her diagnosis of the boys' problems. (MDH)

  3. 33 CFR 100.720 - Annual Suncoast Offshore Grand Prix; Gulf of Mexico, Sarasota, FL.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... of the racecourse. All coordinates referenced use datum: NAD 83. (4) Big Sarasota Pass will be closed... datum: NAD 1983. (b) Special local regulations. (1) No anchoring will be permitted seaward of...

  4. 33 CFR 100.717 - Annual Fort Myers Beach Offshore Grand Prix; Fort Myers, FL.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...°58.30′ W). All coordinates referenced use datum: NAD 83. (b) Special local regulations. (1) No vessel... coordinates referenced use datum: NAD 83. (3) All vessel traffic, not involved with the Fort Myers Beach... clear of the racecourse. All coordinates referenced use datum: NAD 83. (4) All vessel traffic,...

  5. 33 CFR 100.717 - Annual Fort Myers Beach Offshore Grand Prix; Fort Myers, FL.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...°58.30′ W). All coordinates referenced use datum: NAD 83. (b) Special local regulations. (1) No vessel... coordinates referenced use datum: NAD 83. (3) All vessel traffic, not involved with the Fort Myers Beach... clear of the racecourse. All coordinates referenced use datum: NAD 83. (4) All vessel traffic,...

  6. 33 CFR 100.720 - Annual Suncoast Offshore Grand Prix; Gulf of Mexico, Sarasota, FL.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... of the racecourse. All coordinates referenced use datum: NAD 83. (4) Big Sarasota Pass will be closed... datum: NAD 1983. (b) Special local regulations. (1) No anchoring will be permitted seaward of...

  7. 33 CFR 100.720 - Annual Suncoast Offshore Grand Prix; Gulf of Mexico, Sarasota, FL.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... of the racecourse. All coordinates referenced use datum: NAD 83. (4) Big Sarasota Pass will be closed... datum: NAD 1983. (b) Special local regulations. (1) No anchoring will be permitted seaward of...

  8. 33 CFR 100.717 - Annual Fort Myers Beach Offshore Grand Prix; Fort Myers, FL.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...°58.30′ W). All coordinates referenced use datum: NAD 83. (b) Special local regulations. (1) No vessel... coordinates referenced use datum: NAD 83. (3) All vessel traffic, not involved with the Fort Myers Beach... clear of the racecourse. All coordinates referenced use datum: NAD 83. (4) All vessel traffic,...

  9. 33 CFR 100.717 - Annual Fort Myers Beach Offshore Grand Prix; Fort Myers, FL.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...°58.30′ W). All coordinates referenced use datum: NAD 83. (b) Special local regulations. (1) No vessel... coordinates referenced use datum: NAD 83. (3) All vessel traffic, not involved with the Fort Myers Beach... clear of the racecourse. All coordinates referenced use datum: NAD 83. (4) All vessel traffic,...

  10. 33 CFR 100.720 - Annual Suncoast Offshore Grand Prix; Gulf of Mexico, Sarasota, FL.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... of the racecourse. All coordinates referenced use datum: NAD 83. (4) Big Sarasota Pass will be closed... datum: NAD 1983. (b) Special local regulations. (1) No anchoring will be permitted seaward of...

  11. 78 FR 22811 - Special Local Regulations; Mayaguez Grand Prix, Mayaguez Bay; Mayaguez, PR

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-17

    .... SUPPLEMENTARY INFORMATION: Table of Acronyms DHS Department of Homeland Security FR Federal Register NPRM Notice... public dockets in the January 17, 2008, issue of the Federal Register (73 FR 3316). 4. Public Meeting We... individually or cumulatively have a significant effect on the human environment. This proposed rule...

  12. 78 FR 22814 - Special Local Regulations; Miami Super Boat Grand Prix, Atlantic Ocean; Miami Beach, FL

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-17

    ... Department of Homeland Security FR Federal Register NPRM Notice of Proposed Rulemaking A. Public... Federal Register (73 FR 3316). 4. Public Meeting We do not plan to hold a public meeting. But you may... significant effect on the human environment. This proposed rule involves a special local regulation issued...

  13. 78 FR 7331 - SLR; Fajardo Offshore Grand Prix; Rada Fajardo; Fajardo, PR

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-01

    .... SUPPLEMENTARY INFORMATION: Table of Acronyms DHS Department of Homeland Security FR Federal Register NPRM Notice... public dockets in the January 17, 2008, issue of the Federal Register (73 FR 3316). 4. Public Meeting We... individually or cumulatively have a significant effect on the human environment. This proposed rule...

  14. 33 CFR 100.912 - Detroit Bell Isle Grand Prix, Detroit, MI.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Belle Isle located at position 42°20′00″ N; 082°59′45″ W, to 50 yards offshore at position 42°19′57″; 082°59′ 43″, and continuing at a distance of 50 yards around the western end of Belle Isle to the Belle Isle Bridge, maintaining a constant distance of 50 yards from the shoreline and terminating...

  15. 33 CFR 100.717 - Annual Fort Myers Beach Offshore Grand Prix; Fort Myers, FL.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...°58.30′ W). All coordinates referenced use datum: NAD 83. (b) Special local regulations. (1) No vessel... coordinates referenced use datum: NAD 83. (3) All vessel traffic, not involved with the Fort Myers Beach... clear of the racecourse. All coordinates referenced use datum: NAD 83. (4) All vessel traffic,...

  16. 33 CFR 100.720 - Annual Suncoast Offshore Grand Prix; Gulf of Mexico, Sarasota, FL.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... of the racecourse. All coordinates referenced use datum: NAD 83. (4) Big Sarasota Pass will be closed... datum: NAD 1983. (b) Special local regulations. (1) No anchoring will be permitted seaward of...

  17. 75 FR 22333 - Safety Zone; Michigan City Super Boat Grand Prix, Lake Michigan, Michigan City, IN

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-28

    ... FR 3316). Public Meeting We do not now plan to hold a public meeting. But you may submit a request.... This zone is intended to restrict vessels from a portion of Lake Michigan due to high speed power boat... associated with high speed power boat racing. DATES: Comments and related material must be received by...

  18. The MedidaPrix Award: An Agent for Changing Higher Education e-Learning Practice

    NASA Astrophysics Data System (ADS)

    Baumgartner, Peter; Bauer, Reinhard

    With the possibilities of virtual or blended learning environments, remarkable opportunities for new forms of learning have emerged. Responding effectively to this transformation process, we need to capture, honor, and disseminate high quality e-Learning materials and initiate a new sharing mentality.

  19. 33 CFR 100.912 - Detroit Bell Isle Grand Prix, Detroit, MI.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... SECURITY REGATTAS AND MARINE PARADES SAFETY OF LIFE ON NAVIGABLE WATERS § 100.912 Detroit Bell Isle Grand... Detroit River near Belle Isle, bounded by a line extending from a point of land on the southern shore of... position 42°20′28″; 082°59′43″ on the northern side of Belle Isle, adjacent to a point on land at...

  20. 33 CFR 165.158 - Safety Zone: Patchogue Grand Prix, Patchogue Bay, Patchogue, NY.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Sound. (c) Regulations. (1) The general regulations contained in 33 CFR § 165.23 apply. (2) In... zone on VHF-16 or via phone at (203) 468-4401. (d) Enforcement period. This rule will be enforced...

  1. 77 FR 37808 - Special Local Regulation; East Tawas Offshore Gran Prix, Tawas Bay; East Tawas, MI

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-25

    ..., no person or vessel may enter the regulated area without permission of the Captain of the Port. DATES.... SUPPLEMENTARY INFORMATION: Table of Acronyms DHS Department of Homeland Security FR Federal Register NPRM Notice... to wait for a comment period to run would be both impracticable and contrary to the public...

  2. Dynamic observing tonometry (DOT)

    NASA Astrophysics Data System (ADS)

    Kanngiesser, Hartmut E.; Robert, Yves C.

    1999-06-01

    To help improve early detection of vascular eye diseases, a method, named Dynamic Observing Tonometry (DOT), for measuring the intra-ocular pressure (IOP) has been developed, which allows for simultaneous ophthalmoscopy and dynamic tonometry of the human eye. Material and Method. A system for the application of this method is presented, consisting of a transducer to be placed on the corneal surface and of a stand-alone base unit. The latter can be connected to a personal computer for further data processing and storage. The transducer consists of a Goldmann-type contact lens modified by implementing means for transparent pressure-measurement of IOP. A small flat membrane in the center of the lens applanates the cornea. A liquid transmits the applanation pressure from the opposite side of this membrane to a pressure sensor located outside the optical pathway. Time-dependent IOP's are transmitted telemetrically to the base unit for processing. Results. Current initial tests provide evidence for the viability of the concept and have demonstrated the performance of the system. Typical time dependent IOP measurements obtained with an experimental device are presented. Clinical trials with two prototypes are underway. Conclusion: The proposed device allows the ophthalmology to perform the ordinary slit-lamp fundus examinations combined with simultaneous dynamic tonometry. It offers for the first time easy and precise analysis of cardiac and respiratory- modulated intra-ocular pressure while directly observing the choroid and the papilla, as well as the analysis of heart rate variability and inspection of the iridocorneal angle at varying applied pressure. Moreover, dynamic observing tonometry gives easy access to examination procedures such as tonography and ophthalmodynamometry, which have been rarely performed despite their potential diagnostic value due to the complexity of experimental protocols hitherto used.

  3. Pion observables and QCD

    SciTech Connect

    Roberts, C.D.

    1994-09-01

    The Dyson-Schwinger equations (DSEs) are a tower of coupled integral equations that relate the Green functions of QCD to one another. Solving these equations provides the solution of QCD. This tower of equations includes the equation for the quark self-energy, which is the analogue of the gap equation in superconductivity, and the Bethe-Salpeter equation, the solution of which is the quark-antiquark bound state amplitude in QCD. The application of this approach to solving Abelian and non-Abelian gauge theories is reviewed. The nonperturbative DSE approach is being developed as both: (1) a computationally less intensive alternative and; (2) a complement to numerical simulations of the lattice action of QCD. In recent years, significant progress has been made with the DSE approach so that it is now possible to make sensible and direct comparisons between quantities calculated using this approach and the results of numerical simulations of Abelian gauge theories. Herein the application of the DSE approach to the calculation of pion observables is described: the {pi}-{pi} scattering lengths (a{sub 0}{sup 0}, a{sub 0}{sup 2}, A{sub 1}{sup 1}, a{sub 2}{sup 2}) and associated partial wave amplitudes; the {pi}{sup 0} {yields} {gamma}{gamma} decay width; and the charged pion form factor, F{sub {pi}}(q{sup 2}). Since this approach provides a straightforward, microscopic description of dynamical chiral symmetry breaking (D{sub X}SB) and confinement, the calculation of pion observables is a simple and elegant illustrative example of its power and efficacy. The relevant DSEs are discussed in the calculation of pion observables and concluding remarks are presented.

  4. Radar Observations of Asteroids

    NASA Astrophysics Data System (ADS)

    Ostro, S. J.

    2003-05-01

    During the past 25 years, radar investigations have provided otherwise unavailable information about the physical and dynamical properties of more than 200 asteroids. Measurements of the distribution of echo power in time delay and Doppler frequency provide two-dimensional images with spatial resolution as fine as a decameter. Sequences of delay-Doppler images can be used to produce geologically detailed three-dimensional models, to define the rotation state precisely, to constrain the internal density distribution, and to estimate the trajectory of the object's center of mass. Radar wavelengths (4 to 13 cm) and the observer's control of transmitted and received polarizations make the observations sensitive to near-surface bulk density and macroscopic structure. Since delay-Doppler positional measurements are orthogonal to optical angle measurements and typically have much finer fractional precision, they are powerful for refining orbits and prediction ephemerides. Radar astrometry can add decades or centuries to the interval over which an asteroid's close Earth approaches can accurately be predicted and can significantly refine collision probability estimates based on optical astrometry alone. In the highly unlikely case that a small body is on course for an Earth collision in this century, radar reconnaissance would almost immediately distinguish between an impact trajectory and a near miss and would dramatically reduce the difficulty and cost of any effort to prevent the collision. The sizes and rotation periods of radar-detected asteroids span more than four orders of magnitude. These observations have revealed both stony and metallic objects, elongated and nonconvex shapes as well as nearly featureless spheroids, small-scale morphology ranging from smoother than the lunar regolith to rougher than the rockiest terrain on Mars, craters and diverse linear structures, non-principal-axis spin states, contact binaries, and binary systems.

  5. Distributed Observer Network

    NASA Technical Reports Server (NTRS)

    Conroy, Michael; Mazzone, Rebecca; Little, William; Elfrey, Priscilla; Mann, David; Mabie, Kevin; Cuddy, Thomas; Loundermon, Mario; Spiker, Stephen; McArthur, Frank; Srey, Tate; Bonilla, Dennis

    2010-01-01

    The Distributed Observer network (DON) is a NASA-collaborative environment that leverages game technology to bring three-dimensional simulations to conventional desktop and laptop computers in order to allow teams of engineers working on design and operations, either individually or in groups, to view and collaborate on 3D representations of data generated by authoritative tools such as Delmia Envision, Pro/Engineer, or Maya. The DON takes models and telemetry from these sources and, using commercial game engine technology, displays the simulation results in a 3D visual environment. DON has been designed to enhance accessibility and user ability to observe and analyze visual simulations in real time. A variety of NASA mission segment simulations [Synergistic Engineering Environment (SEE) data, NASA Enterprise Visualization Analysis (NEVA) ground processing simulations, the DSS simulation for lunar operations, and the Johnson Space Center (JSC) TRICK tool for guidance, navigation, and control analysis] were experimented with. Desired functionalities, [i.e. Tivo-like functions, the capability to communicate textually or via Voice-over-Internet Protocol (VoIP) among team members, and the ability to write and save notes to be accessed later] were targeted. The resulting DON application was slated for early 2008 release to support simulation use for the Constellation Program and its teams. Those using the DON connect through a client that runs on their PC or Mac. This enables them to observe and analyze the simulation data as their schedule allows, and to review it as frequently as desired. DON team members can move freely within the virtual world. Preset camera points can be established, enabling team members to jump to specific views. This improves opportunities for shared analysis of options, design reviews, tests, operations, training, and evaluations, and improves prospects for verification of requirements, issues, and approaches among dispersed teams.

  6. 2009 Observer Survey Report

    USGS Publications Warehouse

    Crimmins, Theresa M.; Rosemartin, Alyssa H.; Lincicome, Alexis; Weltzin, Jake F.

    2010-01-01

    Survey participants’ suggestions for improving the program fell into several categories, including the need for a more expansive list of plants from which to pick, the ability to monitor animals, and more information on the plants, including photographs of the various phenophases to aid in identification. Participants also requested increased contact from the USA‐NPN, in the form of weekly or monthly emails or newsletters and reminders to collect and submit observations. Many of these suggestions are either already being addressed in changes being made to the monitoring system and online entry system or are planned for the future.

  7. Observations of minor planets.

    NASA Astrophysics Data System (ADS)

    Observations made at the following stations are published: Bucharest, Catania, Caussols, Cent. Astron. Yebes, Cerro Tololo Interam. Obs., Chirorin, Crimean Astrophys. Obs. (52nd Report), Eur. South. Obs., Falkensee, Geisei, Goethe Link Obs., Göttingen, Haute Provence, Hemingford Abbots, JCPM Oi Stn., Kambah (near Canberra), Kitt Peak, Klet', Le Creusot, Lick Obs., Lincoln Lab., Lowell Obs., Lowell Obs. Anderson Mesa Stn., Madonnna di Dossobuono, Mt. John Obs., Mt. Palomar, Oak Ridge Obs., Purple Mountain Obs., Quonochontaug Stn. (Rhode Island), Reintal, S. Vittore (Bologna), Seewalchen, Siding Spring, Skalnaté Pleso, Spec. Astrophys. Obs., Steward Obs., Sydney, Tautenburg, Telford, Tokyo Obs. Kiso Stn., Turku, Zimmerwald.

  8. Television observations of Phobos

    NASA Technical Reports Server (NTRS)

    Avanesov, G. A.; Bonev, B. I.; Boicheva, V.; Kempe, F.; Bazilevskii, A. T.; Duxbury, T.

    1989-01-01

    In February and March 1989 the Phobos 2 spacecraft took 37 television images of Phobos from a distance of 190-1100 km. The data are being used to update the three-dimensional model of Phobos, to provide improved determinations of its density and orbital dynamics, and to study its surface color, composition, and texture. Preliminary findings are presented here which include different integrated photometric behavior in visible and near-infrared bands, observation of a region immediately west of Stickney which is relatively free of large grooves, the prevalence of bright rims on grooves and younger craters, and low bulk density.

  9. Observation of Atomic Antihydrogen

    SciTech Connect

    Blanford, G.; Gollwitzer, K.; Mandelkern, M.; Schultz, J.; Zioulas, G.; Christian, D.C.; Munger, C.T.

    1998-04-01

    We report the background-free observation of atomic antihydrogen, produced by interactions of an antiproton beam with a hydrogen gas jet target in the Fermilab Antiproton Accumulator. We measure the cross section of the reaction {ovr p}p{r_arrow}{ovr H}e{sup {minus}}p for {ovr p} beam momenta between 5203 and 6232 MeV/c to be 1.12{plus_minus}0.14{plus_minus}0.09 pb. {copyright} {ital 1998} {ital The American Physical Society}

  10. The observation of decay

    NASA Astrophysics Data System (ADS)

    Sudbery, A.

    1984-10-01

    It is argued that the usual formulation of quantum mechanics does not satisfactorily describe physical change: the standard formula for a transition probability does not follow from the postulates. Instead, these yield the paradox that a watched pot never bolls (sometimes called "Zeno's paradox"). The paradox is reviewed and the possibility of avoiding it is discussed. A simple model of a decaying system is analysed; the system is then considered in continuous interaction with an apparatus designed to observe the time development of the system. In the light of this analysis, the possibility is considered of replacing the usual (diserete) projection postulate by a continuous projection postulate.

  11. Earth observations - STS-7

    NASA Technical Reports Server (NTRS)

    1983-01-01

    Earth observations - STS-7. North part of Western Australia province, Dampier Land, Fitzroy and Lennard Rivers and the Buccaneer Archipelago (35792); Lake Titicaca, on the Peru-Bolivia border. The Bolivian capital city La Paz is also visible (35793); Denham Sound and Shark Bay in Western Australia are easily recognizable (35794); The Mona Loa Volcano, on the island of Hawaii can be seen in this view. A close look reveals lava flows from the active volcano (35795); Africa; Namibia, Grandberg and Cape Cross, Atlantic Ocean as photographed from the Challenger (35796); View of Venezuela, Aruba, Curacao, and Peninsula de Paraguana (35797).

  12. Copernicus Earth observation programme

    NASA Astrophysics Data System (ADS)

    Žlebir, Silvo

    European Earth observation program Copernicus is an EU-wide programme that integrates satellite data, in-situ data and modeling to provide user-focused information services to support policymakers, researchers, businesses and citizens. Land monitoring service and Emergency service are fully operational already, Atmosphere monitoring service and Marine environment monitoring service are preoperational and will become fully operational in the following year, while Climate change service and Security service are in an earlier development phase. New series of a number of dedicated satellite missions will be launched in the following years, operated by the European Space Agency and EUMETSAT, starting with Sentinel 1A satellite early this year. Ground based, air-borne and sea-borne in-situ data are provided by different international networks and organizations, EU member states networks etc. European Union is devoting a particular attention to secure a sustainable long-term operational provision of the services. Copernicus is also stated as a European Union’s most important contribution to Global Earth Observation System of Systems (GEOSS). The status and the recent development of the Copernicus programme will be presented, together with its future perspective. As Copernicus services have already demonstrated their usability and effectiveness, some interesting cases of their deployment will be presented. Copernicus free and open data policy, supported by a recently adopted EU legislative act, will also be presented.

  13. Ulysses: UVCS Coordinated Observations

    NASA Technical Reports Server (NTRS)

    Suess, S. T.; Poletto, G.; Corti, G.; Simnett, G.; Noci, G.; Romoli, M.; Kohl, J.; Goldstein, B.

    1998-01-01

    We present results from coordinated observations in which instruments on Solar and Heliospheric Observatory (SOHO) and Ulysses were used to measure the density and flow speed of plasma at the Sun and to again measure the same properties of essentially the same plasma in the solar wind. Plasma was sampled by Ultraviolet Coronagraph Spectrometer (UVCS) at 3.5 and 4.5 solar radii and by Ulysses/SWOOPS at 5 AU. Data were acquired during a nearly 2 week period in May-June 1997 at a latitude of 9-10 degrees north of the equator, on the east limb and, hence, in the streamer belt and the source location of slow wind. Density and outflow speed are compared, in order to check for preservation of the near Sun characteristics in the interplanetary medium. By chance, Ulysses was at the very northern edge of the visible streamer belt. Nevertheless, no evidence of fast wind, or mixing with fast wind coming from the northern polar coronal hole, was evident at Ulysses. The morphology of the streamer belt was similar at the beginning and end of the observation period, but was markedly different during the middle of the period. A corresponding change in density (but not flow speed) was noted at Ulysses.

  14. Observations of glitches

    NASA Astrophysics Data System (ADS)

    Espinoza, Cristobal

    2016-07-01

    Glitches are sudden spin ups observed in the otherwise smooth rotation of pulsars. These rare and rather small events are thought to be caused by an erratic relationship between a loosely coupled internal superfluid and the crust of the neutron star. They are known to be one of the very few phenomena which allow us to study the interior of pulsars. The largest events are followed by a period of relaxation, lasting from month to years, in which the rotation evolves back to the pre-glitch state. These recoveries might represent the response of internal superfluid components to the sudden change in rotation at the glitch. Therefore, the study and comprehension of glitches and their recoveries provide ways to refine our understanding of superfluid physics in the extreme and unique conditions present inside neutron stars. In this talk I will summarise the current observational status of glitch research. This will include not only the detection of new glitches but also the analysis of our detection capabilities and the design of monitoring campaigns that could deliver a wider range of detections. I will also present ongoing research on the glitch size distribution of particular sources and some recent results regarding the long-term effects that glitch recoveries pose on pulsar spin evolution.

  15. Exoplanet observations with GTC

    NASA Astrophysics Data System (ADS)

    Pallé, Enric

    2015-12-01

    Our group is presently conducting an observational campaign, using the 10-meter Gran Telescopio Canarias (GTC), to obtain the transmission spectrum of several exoplanets during a transit event. The GTC instrument OSIRIS is used in its long-slit spectroscopic mode, covering the spectral range of 520-1040 nm, and observations are taken using a set of custom-built slits of various, broad, widths. We integrate the stellar flux of both stars in different wavelength regions producing several light curves and fit transit models in order to obtain the star-to-planet radius ratio Rp/Rs across wavelength. A Markov Chain Monte Carlo (MCMC) Bayesian approach is used for the transit fitting. We will show that with our instrumental setup, OSIRIS has been able to reach precisions down to 250 ppm (WASP-48b, V=11.06 mag) for each color light curve 10 nm wide, in a single transit. And accuracies of the order of 500ppm can be obtained for objects with V=16. Central transit timing accuracies have been measured down to 6 seconds.Here, we will present refined planet parameters, the detection of planet color signatures, and the transmission spectra of a set of know and unpublished transiting exoplanets. We will also discuss the capabilities and limitations of GTC with current and future instrumentation, and the role of GTC as tool for the follow up of faint exoplanet targets.

  16. Commercial Earth Observation

    NASA Technical Reports Server (NTRS)

    1995-01-01

    Through the Earth Observation Commercial Applications Program (EOCAP) at Stennis Space Center, Applied Analysis, Inc. developed a new tool for analyzing remotely sensed data. The Applied Analysis Spectral Analytical Process (AASAP) detects or classifies objects smaller than a pixel and removes the background. This significantly enhances the discrimination among surface features in imagery. ERDAS, Inc. offers the system as a modular addition to its ERDAS IMAGINE software package for remote sensing applications. EOCAP is a government/industry cooperative program designed to encourage commercial applications of remote sensing. Projects can run three years or more and funding is shared by NASA and the private sector participant. Through the Earth Observation Commercial Applications Program (EOCAP), Ocean and Coastal Environmental Sensing (OCENS) developed SeaStation for marine users. SeaStation is a low-cost, portable, shipboard satellite groundstation integrated with vessel catch and product monitoring software. Linked to the Global Positioning System, SeaStation provides real time relationships between vessel position and data such as sea surface temperature, weather conditions and ice edge location. This allows the user to increase fishing productivity and improve vessel safety. EOCAP is a government/industry cooperative program designed to encourage commercial applications of remote sensing. Projects can run three years or more and funding is shared by NASA and the private sector participant.

  17. AH Her Observing Campaign

    NASA Astrophysics Data System (ADS)

    Waagen, Elizabeth O.

    2013-05-01

    Dr. Juan Echevarria (Universidad Nacional Autónoma de México) and colleagues request AAVSO assistance in a campaign on the Z Cam-type cataclysmic variable AH Her being carried out 2013 May 29 - June 18. They will be making photometric and spectroscopic observations of AH Her using the 2.1m and 0.84m telescopes at San Pedro Martir Observatory (SPM). Their goal is to carry out a radial velocity study of the system components using modern detectors; no study of AH Her has been made since the one by Horne, Wade, and Szkody in 1980-1981 (1986MNRAS.219..791H). Photometry and spectroscopy are requested. AH Her, for decades a reasonably "regular" Z Cam system, began exhibiting significantly anomalous behavior in ~2007. Since then it has experienced brief periods of fairly typical behavior interspersed with more anomalous intervals, including some unprecedented behavior. Most recently, it has returned to a more normal pattern of outbursts shape-wise but it is not back to its normal amplitude or frequency. AAVSO data will be essential for correlation in order to determine the precise time(s) of minimum occurring during the campaign. Finder charts with sequences may be created using the AAVSO Variable Star Plotter (http://www.aavso.org/vsp). Observations should be submitted to the AAVSO International Database. See full Alert Notice for more details.

  18. Stereoscopically Observing Manipulative Actions.

    PubMed

    Ferri, S; Pauwels, K; Rizzolatti, G; Orban, G A

    2016-08-01

    The purpose of this study was to investigate the contribution of stereopsis to the processing of observed manipulative actions. To this end, we first combined the factors "stimulus type" (action, static control, and dynamic control), "stereopsis" (present, absent) and "viewpoint" (frontal, lateral) into a single design. Four sites in premotor, retro-insular (2) and parietal cortex operated specifically when actions were viewed stereoscopically and frontally. A second experiment clarified that the stereo-action-specific regions were driven by actions moving out of the frontoparallel plane, an effect amplified by frontal viewing in premotor cortex. Analysis of single voxels and their discriminatory power showed that the representation of action in the stereo-action-specific areas was more accurate when stereopsis was active. Further analyses showed that the 4 stereo-action-specific sites form a closed network converging onto the premotor node, which connects to parietal and occipitotemporal regions outside the network. Several of the specific sites are known to process vestibular signals, suggesting that the network combines observed actions in peripersonal space with gravitational signals. These findings have wider implications for the function of premotor cortex and the role of stereopsis in human behavior. PMID:27252350

  19. The ANTARES observation network

    NASA Astrophysics Data System (ADS)

    Dogliotti, Ana I.; Ulloa, Osvaldo; Muller-Karger, Frank; Hu, Chuanmin; Murch, Brock; Taylor, Charles; Yuras, Gabriel; Kampel, Milton; Lutz, Vivian; Gaeta, Salvador; Gagliardini, Domingo A.; Garcia, Carlos A. E.; Klein, Eduardo; Helbling, Walter; Varela, Ramon; Barbieri, Elena; Negri, Ruben; Frouin, Robert; Sathyendranath, Shubha; Platt, Trevor

    2005-08-01

    The ANTARES network seeks to understand the variability of the coastal environment on a continental scale and the local, regional, and global factors and processes that effect this change. The focus are coastal zones of South America and the Caribbean Sea. The initial approach includes developing time series of in situ and satellite-based environmental observations in coastal and oceanic regions. The network is constituted by experts that seek to exchange ideas, develop an infrastructure for mutual logistical and knowledge support, and link in situ time series of observations located around the Americas with real-time and historical satellite-derived time series of relevant products. A major objective is to generate information that will be distributed publicly and openly in the service of coastal ocean research, resource management, science-based policy making and education in the Americas. As a first stage, the network has linked oceanographic time series located in Argentina, Brazil, Chile and Venezuela. The group has also developed an online tool to examine satellite data collected with sensors such as NASA's MODIS. Specifically, continental-scale high-resolution (1 km) maps of chlorophyll and of sea surface temperature are generated and served daily over the web according to specifications of users within the ANTARES network. Other satellite-derived variables will be added as support for the network is solidified. ANTARES serves data and offers simple analysis tools that anyone can use with the ultimate goal of improving coastal assessments, management and policies.

  20. Observing inflationary reheating.

    PubMed

    Martin, Jérôme; Ringeval, Christophe; Vennin, Vincent

    2015-02-27

    Reheating is the epoch which connects inflation to the subsequent hot big-bang phase. Conceptually very important, this era is, however, observationally poorly known. We show that the current Planck satellite measurements of the cosmic microwave background (CMB) anisotropies constrain the kinematic properties of the reheating era for most of the inflationary models. This result is obtained by deriving the marginalized posterior distributions of the reheating parameter for about 200 models of slow-roll inflation. Weighted by the statistical evidence of each model to explain the data, we show that the Planck 2013 measurements induce an average reduction of the posterior-to-prior volume by 40%. Making some additional assumptions on reheating, such as specifying a mean equation of state parameter, or focusing the analysis on peculiar scenarios, can enhance or reduce this constraint. Our study also indicates that the Bayesian evidence of a model can substantially be affected by the reheating properties. The precision of the current CMB data is therefore such that estimating the observational performance of a model now requires incorporating information about its reheating history. PMID:25768752

  1. GLOBAL OBSERVATIONS FROM PHOBOS.

    SciTech Connect

    BAKER,M.D.; FOR THE PHOBOS COLLABORATION

    2002-07-18

    Particle production in Au+Au collisions has been measured in the PHOBOS experiment at RHIC for a range of collision energies. Three empirical observations have emerged from this dataset which require theoretical examination. First, there is clear evidence of limiting fragmentation. Namely, particle production in central Au + Au collisions, when expressed as dN/d{eta}{prime} ({eta}{prime} {triple_bond} {eta} - y{sub beam}), becomes energy independent at high energy for a broad region of {eta}{prime} around {eta}{prime} = 0. This energy-independent region grows with energy, allowing only a limited region (if any) of longitudinal boost-invariance. Second, there is a striking similarity between particle production in e{sup +}e{sup -} and Au + Au collisions (scaled by the number of participating nucleon pairs). Both the total number of produced particles and the longitudinal distribution of produced particles are approximately the same in e{sup +}e{sup -} and in scaled Au + Au. This observation was not predicted and has not been explained. Finally, particle production has been found to scale approximately with the number of participating nucleon pairs for > 65. This scaling occurs both for the total multiplicity and for high p{sub T} particles (3 < p{sub T} < 4.5 GeV/c).

  2. Stereoscopically Observing Manipulative Actions

    PubMed Central

    Ferri, S.; Pauwels, K.; Rizzolatti, G.; Orban, G. A.

    2016-01-01

    The purpose of this study was to investigate the contribution of stereopsis to the processing of observed manipulative actions. To this end, we first combined the factors “stimulus type” (action, static control, and dynamic control), “stereopsis” (present, absent) and “viewpoint” (frontal, lateral) into a single design. Four sites in premotor, retro-insular (2) and parietal cortex operated specifically when actions were viewed stereoscopically and frontally. A second experiment clarified that the stereo-action-specific regions were driven by actions moving out of the frontoparallel plane, an effect amplified by frontal viewing in premotor cortex. Analysis of single voxels and their discriminatory power showed that the representation of action in the stereo-action-specific areas was more accurate when stereopsis was active. Further analyses showed that the 4 stereo-action-specific sites form a closed network converging onto the premotor node, which connects to parietal and occipitotemporal regions outside the network. Several of the specific sites are known to process vestibular signals, suggesting that the network combines observed actions in peripersonal space with gravitational signals. These findings have wider implications for the function of premotor cortex and the role of stereopsis in human behavior. PMID:27252350

  3. Observations of Distant Clusters

    NASA Technical Reports Server (NTRS)

    Donahue, Megan

    2004-01-01

    The is the proceedings and papers supported by the LTSA grant: Homer, D. J.\\& Donahue, M. 2003, in "The Emergence of Cosmic Structure": 13'h Astrophysics Conference Proceedings, Vol. 666,3 1 1-3 14, (AIP). Baumgartner, W. H., Loewenstein, M., Horner, D. J., Mushotzky, R. F. 2003, HEAD- AAS, 35.3503. Homer, D. J. , Donahue, M., Voit G. M. 2003, HEAD-AAS, 35.1309. Nowak, M. A., Smith, B., Donahue, M., Stocke, J. 2003, HEAD-AAS, 35.1316. Scott, D., Borys, C., Chapman, S. C., Donahue, M., Fahlman, G. G., Halpem, M. Newbury, P. 2002, AAS, 128.01. Jones, L. R. et al. 2002, A new era in cosmology, ASP Conference Proceedings, Vol. 283, p. 223 Donahue, M., Daly, R. A., Homer, D. J. 2003, ApJ, 584, 643, Constraints on the Cluster Environments and Hotspot magnetic field strengths for radio sources 3280 and 3254. Donahue, M., et al. 2003, ApJ, 598, 190. The mass, baryonic fraction, and x-ray temperature of the luminous, high-redshift cluster of galaxies MS045 1.6-0305 Perlman, E. S. et al. 2002, ApJS, 140, 256. Smith, B. J., Nowak, M., Donahue, M., Stocke, J. 2003, AJ, 126, 1763. Chandra Observations of the Interacting NGC44 10 Group of Galaxies. Postman, M., Lauer, T. R., Oegerle, W., Donahue, M. 2002, ApJ, 579, 93. The KPNO/deep-range cluster survey I. The catalog and space density of intermediate-redshift clusters. Molnar, S. M., Hughes, J. P., Donahue, M., Joy, M. 2002, ApJ, 573, L91, Chandra Observations of Unresolved X-Ray Sources around Two Clusters of Galaxies. Donahue, M., Mack, J., 2002 NewAR, 46, 155, HST NIcmos and WFPC2 observations of molecular hydrogen and dust around cooling flows. Koekemoer, A. M. et al. 2002 NewAR, 46, 149, Interactions between the A2597 central radio source and dense gas host galaxy. Donahue, M. et al. 2002 ApJ, 569,689, Distant cluster hunting II.

  4. AAVSO Solar Observers Worldwide

    NASA Astrophysics Data System (ADS)

    Howe, R.

    2013-06-01

    (Abstract only) For visual solar observers there has been no biological change in the "detector" (human eye) - at century scales (eye + visual cortex) does not change much over time. Our capacity to "integrate" seeing distortions is not just simple averaging! The visual cortex plays an essential role, and until recently only the SDO-HMI (Solar Dynamics Observatory, Helioseismic and Magnetic Imager) has had the capacity to detect the smallest sunspots, called pores. Prior to this the eye was superior to photography and CCD. Imaged data are not directly comparable or substitutable to counts by eye, as the effects of sensor/optical resolution and seeing will have a different influence on the resulting sunspot counts for images when compared to the human eye. Also contributing to the complex task of counting sunspots is differentiating between a sunspot (which is usually defined as having a darker center (umbra) and lighter outer ring (penumbra)) and a pore, made even more complex by the conflicting definitions of the word "pore" in the solar context: "pore" can mean a small spot without penumbra or "pore" can mean a random intergranular blemish that is not a true sunspot. The overall agreement is that the smallest spot size is near 2,000 km or ~3 arc sec, (Loughhead, R. E. and Bray, R. J. 1961, Australian J. Phys., 14, 347). Sunspot size is dictated by granulation dynamics rather than spot size (cancellation of convective motion), and by the lifetime of the pore, which averages from 10 to 30 minutes. There is no specific aperture required for AAVSO observers contributing sunspot observations. However, the detection of the smallest spots is influenced by the resolution of the telescope. Two factors to consider are the theoretical optical resolution (unobstructed aperture), Rayleigh criterion: theta = 138 / D(mm), and Dawes criterion: theta = 116 / D(mm) (http://www.telescope-optics.net/telescope_resolution.htm). However, seeing is variable with time; daytime range will

  5. Little Ice Age versus Present Day: Comparison of Temperature, Precipitation and Seasonality in Speleothem Records from the Han-sur-Lesse Cave, Belgium.

    NASA Astrophysics Data System (ADS)

    Vansteenberge, S.; Van Opdenbosch, J.; Van Rampelbergh, M.; Verheyden, S.; Keppens, E.; Cheng, H.; Edwards, R. L.; Claeys, P. F.

    2015-12-01

    The Proserpine stalagmite is a 2 m large, tabular-shaped speleothem located in the Han-sur-Lesse cave in Belgium. The speleothem formed over the last 1000 years and is still growing. High-accuracy U/Th datings have indicated exceptionally high growth-rates of up to 2 mm per year. This, together with a well expressed annual layering, makes the Proserpine stalagmite an ideal candidate for high-resolution paleoclimate reconstructions of the last millennium. Previous work, including over 10 years of cave monitoring, has already learned us how short-term, i.e. decadal to seasonal, climate variations are incorporated within speleothem calcite from the Han-sur-Lesse cave system. It has been shown that δ18O and δ13C stable isotopes and trace element proxies of recently formed calcite reflect seasonal variations in temperature and precipitation of the near-cave environment (Verheyden et al, 2008; Van Rampelbergh et al., 2014). Now, this knowledge was used to infer local climate parameters further back in time to the period of +/- 1620-1630 CE, corresponding to one of the cold peaks within the Little Ice Age. Speleothem calcite was sampled at sub-annual resolution, with approximately 11 samples per year, for stable isotope analysis. LA-ICP-MS and µXRF analyses resulted in time series of trace elements. Preliminary results indicate a well expressed seasonal signal in δ13C and trace element composition but a multi-annual to decadal trend in δ18O. This combined proxy study eventually enables comparison of the expression of seasonality and longer term climate variations between a Little Ice Age cold peak and Present Day. References: Verheyden, S. et al., 2008, Monitoring climatological, hydrological and geochemical parameters in the Père Noël cave (Belgium): implication for the interpretation of speleothem isotopic and geochemical time-series. International Journal of Speleology, 37(3), 221-234. Van Rampelbergh, M. et al., 2014, Seasonal variations recorded in cave

  6. Catalyseur d'hydrocraquage à base de sulfure de NiMo déposé sur une zéolithe HEMT modifiée

    NASA Astrophysics Data System (ADS)

    Baalala, M.; Becue, T.; Leglise, J.; Manoli, J. M.; van Gestel, J. N. M.; Lamotte, J.; Bensitel, M.; Goupil, J. M.; Cornet, D.

    1999-02-01

    Treating a NH4EMT zeolite with a solution of (NH4)2SiF6 at 80 °C affords a solid containing amorphous SiO2 intimately mixed with the zeolite. This acidic support EMT-Si was loaded with NiMo sulfide in order to prepare a bifunctional catalyst, which was tested for the hydrogenation of benzene and the hydrocracking of n-heptane. This NiMo/EMT-Si catalyst was found more active for hydrogenation than the analogous NiMo/HY. This is ascribed to a higher dispersion of the NiMo sulfide, which is almost equally shared between the internal mesopores in the modified EMT solid, and the fissures, which were created throughout the zeolite grains upon inserting the NiMo sulfide. The catalyst with the EMT-Si support was also found more active than the NiMo/HY for the hydrocracking of heptane, with a slightly higher selectivity into heptane isomers. Le traitement d'une zéolithe NH4EMT par une solution de (NH4)2SiF6 fournit un solide comportant une phase SiO2 amorphe intimement mélangée aux parties intactes de la zéolithe. Sur ce support acide EMT-Si, on a greffé un sulfure de NiMo afin de préparer un catalyseur bifonctionnel qui a été testé dans les réactions d'hydrogénation du benzène et d'hydrocraquage du n-heptane. Ce catalyseur NiMo/EMT-Si s'avère plus actif en hydrogénation que son analogue NiMo/HY, en raison d'une meilleure dispersion du sulfure de NiMo. Sur le solide EMT modifié, le sulfure se répartit à peu près également entre les mésopores internes et les fissures crées dans les grains de zéolithe lors de l'insertion du sulfure de NiMo. Au contraire sur le support Y, une partie du sulfure est externe aux grains de zéolithe et inactive en catalyse. Le catalyseur NiMo/EMT-Si est aussi trouvé plus actif que le NiMo/HY en hydrocraquage du n-heptane, et un peu plus sélectif en isomères.

  7. Électrooxydation du mésoérythritol sur platine, modifié ou non par des adatomes, en milieu acide

    NASA Astrophysics Data System (ADS)

    Cherqaoui, A.; Chbihi, M. El M.; Takky, D.; Kokoh, K. B.; Leger, J.-M.; Lamy, C.

    1999-03-01

    The electrocatalytic oxidation of meso-erythritol has been studied in 0.1 M HClO4 on platinum and on adatoms modified platinum. Preliminary investigations by cyclic voltammetry showed that erythritol was not reactive on a Pt electrode. Underpotential deposition of lead or thallium adatoms at platinum allowed to increase significantly the current densities. Long-time electrolyses were carried out using a three potential plateau program with different values of the oxidation potentials. Chromatographic analyses showed that the oxidation of erythritol led mainly to erythrose, erythrulose and to erythronic acid. Otherwise, electrolysis of erythritol on a Pt-Tl modified electrode orientated selectively the distribution of the reaction products towards the formation of erythrulose. L'oxydation électrocatalytique du mésoérythrytol a été étudiée en milieu acide HClO4 0,1 M sur le platine modifié ou non par des adatomes métalliques. Les études préliminaires réalisées par voltammétrie cyclique montrent que l'érythritol est très peu réactif sur le platine seul. La modification de la surface de l'électrode par dépôt en sous-tension d'adatomes de plomb et de thallium permet d'augmenter les densités de courant. Les électrolyses prolongées sont réalisées à l'aide d'un programme à trois paliers de potentiel et pour différentes valeurs de potentiel d'oxydation. Les analyses chromatographiques montrent que les produits d'oxydation sont l'érythrose, l'érythrulose et l'acide érythronique. D'autre part l'oxydation de l'érythritol sur le platine modifié par des adatomes de thallium conduit à une production sélective d'érythrulose.

  8. Ion Outflow Observations

    NASA Technical Reports Server (NTRS)

    Mellot, Mary (Technical Monitor)

    2002-01-01

    The characteristics of out-flowing ions have been investigated under various circumstances. In particular the upwelling of ions from the cleft region has been studied to attempt to look at source characteristics (e.g., temperature, altitude). High altitude (6-8 Re) data tend to show ions species that have the same velocity and are adiabatically cooled. Such ions, while representative of their source, can not provide an accurate picture. Ion observations from the TIDE detector on the Polar spacecraft show an energy (or equivalently a velocity) spectrum of ions as they undo the geomagnetic mass spectrometer effect due to convection-gravity separation of the different species. Consolidation of this type of data into a complete representation of the source spectrum can be attempted by building a set of maximum-phase-space- density-velocity pairs and attributing the total to the source.

  9. The Mars Observer Mission

    NASA Technical Reports Server (NTRS)

    Palluconi, F. D.

    1985-01-01

    The Mars Observer Mission is to be the first in a series of modest-cost inner-planet missions. Launch is planned for the August/September 1990 Mars opportunity with arrival at Mars one year later. The geoscience/climatology objectives are to be met during a mapping mission over the course of one Mars year (687 days). The mapping orbit will be near-polar (93 degree orbital inclination), sun-synchronous (2 PM sunward equator crossing), and near-circular (350 km orbit altitude, 116 minute period). The spacecraft, to be selected in late 1985, will be a modified version of an existing commercial design which, in the mapping orbit, will maintain a nadir orientation. Experiments and instruments will be selected through an Announcement of Opportunity (AO) process with release of the AO in April 1985, and selection in early 1986. A description of current planning for this mission, with emphasis on climatology, is presented here.

  10. SAMPEX Relativistic Microbursts Observation

    NASA Astrophysics Data System (ADS)

    Liang, X.; Comess, M.; Smith, D. M.; Selesnick, R. S.; Sample, J. G.; Millan, R. M.

    2012-12-01

    Relativistic (>1 MeV) electron microburst precipitation is thought to account for significant relativistic electron loss. We present the statistical and spectral analysis of relativistic microbursts observed by the Proton/Electron Telescope (PET) on board the Solar Anomalous Magnetospheric Particle Explorer(SAMPEX) satellite from 1992 to 2004. Spectrally we find that microbursts are well fit by an exponential energy distribution in the 0.5-4 MeV range with a spectral e-folding energy of E0 < 375 keV. We also discuss the comparison of morning microbursts with events at midnight, which were first identified as microbursts by O'Brien et al. (2004). Finally, we compare the loss-rates due to microbursts and non-microburst precipitation during storm times and averaged over all times.

  11. Spatial Standard Observer

    NASA Technical Reports Server (NTRS)

    Watson, Andrw B. (Inventor)

    2010-01-01

    The present invention relates to devices and methods for the measurement and/or for the specification of the perceptual intensity of a visual image. or the perceptual distance between a pair of images. Grayscale test and reference images are processed to produce test and reference luminance images. A luminance filter function is convolved with the reference luminance image to produce a local mean luminance reference image . Test and reference contrast images are produced from the local mean luminance reference image and the test and reference luminance images respectively, followed by application of a contrast sensitivity filter. The resulting images are combined according to mathematical prescriptions to produce a Just Noticeable Difference, JND value, indicative of a Spatial Standard Observer. SSO. Some embodiments include masking functions. window functions. special treatment for images lying on or near border and pre-processing of test images.

  12. Skylab Earth Observation Studies

    NASA Technical Reports Server (NTRS)

    1972-01-01

    This concept illustrates Skylab Earth observation studies, an Earth Resources Experiment Package (EREP). EREP was designed to explore the use of the widest possible portion of the electromagnetic spectrum for Earth resource investigations with sensors that recorded data in the visible, infrared, and microwave spectral regions. Resources subject to this study included a capability of mapping Earth resources and land uses, crop and forestry cover, health of vegetation, types of soil, water storage in snow pack, surface or near-surface mineral deposits, sea surface temperature, and the location of likely feeding areas for fish, etc. A significant feature of EREP was the ability of man to operate the sensors in a laboratory fashion.

  13. Spatial Standard Observer

    NASA Technical Reports Server (NTRS)

    Watson, Andrew B. (Inventor)

    2012-01-01

    The present invention relates to devices and methods for the measurement and/or for the specification of the perceptual intensity of a visual image, or the perceptual distance between a pair of images. Grayscale test and reference images are processed to produce test and reference luminance images. A luminance filter function is convolved with the reference luminance image to produce a local mean luminance reference image. Test and reference contrast images are produced from the local mean luminance reference image and the test and reference luminance images respectively, followed by application of a contrast sensitivity filter. The resulting images are combined according to mathematical prescriptions to produce a Just Noticeable Difference, JND value, indicative of a Spatial Standard Observer, SSO. Some embodiments include masking functions, window functions, special treatment for images lying on or near borders and pre-processing of test images.

  14. VERITAS Galactic Observations

    NASA Astrophysics Data System (ADS)

    Hughes, Gareth

    2013-06-01

    We report on recent Galactic results and discoveries made by the VERITAS collaboration. The Very Energetic Radiation Imaging Telescope Array System (VERITAS) is a ground-based gamma-ray observatory, located in southern Arizona, able to detect gamma rays of energies from 100 GeV up to 30 TeV. VERITAS has been fully operational since 2007 and its current sensitivity enables the detection of a 1% Crab Nebula flux at 5 sigma in under 30 hours. The observatory is well placed to view large parts of the galactic plane including its center, resulting in a strong galactic program. Objects routinely observed include Pulsars, Pulsar Wind Nebula, X-ray binaries and sources with unidentified counterparts in other wavelengths.

  15. Propellers: Theory and observation

    NASA Astrophysics Data System (ADS)

    Sremcevic, M.

    2007-12-01

    The question on the origin and evolution of planetary rings is one of the prominent unsolved problems of planetary sciences with direct implications for planet-forming processes in preplanetary disks. The recent detection of four propeller-shaped features in Saturn's A ring (Tiscareno et al., 2006) proved the presence of large boulder-sized moonlets in the rings (Spahn & Sremcevic, 2000). Their very existence favors a ring creation in a catastrophic disruption of an icy satellite (Sremcevic et al., 2007) rather than a co-genetic origin with Saturn, since bodies of this size can hardly have accreted inside the rings. Here we will review the current state of theoretical modeling and Cassini observations.

  16. Equilibration by quantum observation

    NASA Astrophysics Data System (ADS)

    Gordon, Goren; Bhaktavatsala Rao, D. D.; Kurizki, Gershon

    2010-05-01

    We consider an unexplored regime of open quantum systems that relax via coupling to a bath while being monitored by an energy meter. We show that any such system inevitably reaches an equilibrium (quasi-steady) state controllable by the effective rate of monitoring. In the non-Markovian regime, this approach suggests the possible 'freezing' of states, by choosing monitoring rates that set a non-thermal equilibrium state to be the desired one. For measurement rates high enough to cause the quantum Zeno effect, the only steady state is the fully mixed state, due to the breakdown of the rotating wave approximation. Regardless of the monitoring rate, all the quasi-steady states of an observed open quantum system live only as long as the Born approximation holds, namely the bath entropy does not change. Otherwise, both the system and the bath converge to their fully mixed states.

  17. Quadrature, Interpolation and Observability

    NASA Technical Reports Server (NTRS)

    Hodges, Lucille McDaniel

    1997-01-01

    Methods of interpolation and quadrature have been used for over 300 years. Improvements in the techniques have been made by many, most notably by Gauss, whose technique applied to polynomials is referred to as Gaussian Quadrature. Stieltjes extended Gauss's method to certain non-polynomial functions as early as 1884. Conditions that guarantee the existence of quadrature formulas for certain collections of functions were studied by Tchebycheff, and his work was extended by others. Today, a class of functions which satisfies these conditions is called a Tchebycheff System. This thesis contains the definition of a Tchebycheff System, along with the theorems, proofs, and definitions necessary to guarantee the existence of quadrature formulas for such systems. Solutions of discretely observable linear control systems are of particular interest, and observability with respect to a given output function is defined. The output function is written as a linear combination of a collection of orthonormal functions. Orthonormal functions are defined, and their properties are discussed. The technique for evaluating the coefficients in the output function involves evaluating the definite integral of functions which can be shown to form a Tchebycheff system. Therefore, quadrature formulas for these integrals exist, and in many cases are known. The technique given is useful in cases where the method of direct calculation is unstable. The condition number of a matrix is defined and shown to be an indication of the the degree to which perturbations in data affect the accuracy of the solution. In special cases, the number of data points required for direct calculation is the same as the number required by the method presented in this thesis. But the method is shown to require more data points in other cases. A lower bound for the number of data points required is given.

  18. Effet de la concentration du cuivre ou de l'argent sur les propriétés des agrégats de rhodium déposés sur silice amorphe dans l'hydrogénation du 1,3 butadiène

    NASA Astrophysics Data System (ADS)

    Ksibi, Z.; Ghorbel1, A.; Bellamy, B.

    1999-02-01

    Some samples with rhodium, rhodium-copper and rhodium-silver deposited on amorphous silica by vapor deposition of the metallic phase under high-vacuum (P < 5.10-7 Pa) have been prepared. The effect of rhodium cluster size and copper or silver addition on catalytic properties of rhodium in the 1,3 butadiène hydrogenation was studied. Results show that the reaction is sensitive to the size of rhodium aggregates and that there is an important difference between the effect of copper and silver on the rhodium properties. Indeed copper forms an alloy with rhodium and provokes a poison effect on the activity of the noble metal, whereas silver exhibits a mask effect on the rhodium particles without forming alloy with it. Des échantillons mono-métalliques au rhodium et bimétalliques rhodium-cuivre et rhodium-argent déposés sur une silice amorphe par vapodéposition d'une phase métallique dans des conditions ultra-vide (P < 5.10-7 Pa) ont été préparés. L'effet de la taille des agrégats de rhodium ainsi que celui de l'addition du cuivre ou de l'argent sur les propriétés catalytiques du rhodium dans l'hydrogénation du 1,3 butadiène ont été étudiés. Les résultats montrent que la réaction étudiée est sensible à la taille des agrégats de rhodium et nous notons une différence importante entre l'effet du cuivre et de l'argent sur les propriétés du rhodium. En effet le cuivre forme un alliage avec le rhodium et provoque un effet poison d?où une modification de l'activité du métal noble, alors que l'argent exerce un effet de masque sur les particules de rhodium sans toutefois former d'alliage avec ce dernier.

  19. Caracterisation, modelisation et validation du transfert radiatif d'atmospheres non standard; impact sur les corrections atmospheriques d'images de teledetection

    NASA Astrophysics Data System (ADS)

    Zidane, Shems

    This study is based on data acquired with an airborne multi-altitude sensor on July 2004 during a nonstandard atmospheric event in the region of Saint-Jean-sur-Richelieu, Quebec. By non-standard atmospheric event we mean an aerosol atmosphere that does not obey the typical monotonic, scale height variation employed in virtually all atmospheric correction codes. The surfaces imaged during this field campaign included a diverse variety of targets : agricultural land, water bodies, urban areas and forests. The multi-altitude approach employed in this campaign allowed us to better understand the altitude dependent influence of the atmosphere over the array of ground targets and thus to better characterize the perturbation induced by a non-standard (smoke) plume. The transformation of the apparent radiance at 3 different altitudes into apparent reflectance and the insertion of the plume optics into an atmospheric correction model permitted an atmospheric correction of the apparent reflectance at the two higher altitudes. The results showed consistency with the apparent validation reflectances derived from the lowest altitude radiances. This approach effectively confirmed the accuracy of our non-standard atmospheric correction approach. This test was particularly relevant at the highest altitude of 3.17 km : the apparent reflectances at this altitude were above most of the plume and therefore represented a good test of our ability to adequately correct for the influence of the perturbation. Standard atmospheric disturbances are obviously taken into account in most atmospheric correction models, but these are based on monotonically decreasing aerosol variations with increasing altitude. When the atmospheric radiation is affected by a plume or a local, non-standard pollution event, one must adapt the existing models to the radiative transfer constraints of the local perturbation and to the reality of the measurable parameters available for ingestion into the model. The

  20. Gold pickings and PIXE analysis. More about the Bronze age gold found in the cave of Han-sur-Lesse (Namur, Belgium)

    NASA Astrophysics Data System (ADS)

    Warmenbol, Eugène

    2004-11-01

    Gold remains a rare material during the whole Bronze Age. It is a metal that circulates amongst the elites exclusively. The exchange of gold artefacts over very long distances is fundamental in the build-up of socio-political relations. Fifty artefacts found during subaquatic excavations in the river Lesse in the cave of Han-sur-Lesse have been submitted to quantitative elemental analysis using PIXE, a method never used before on archaeological material found in Belgium. The results show that there are clearly three groups of artefacts. The first one (discs, "baskets", pearls) proves of local manufacture, as also suggested by the discovery of two ingots. The second one (gilded rings) could have been locally made too, but is a lot less homogeneous. The third one (filigreed and granulated beads or pin's heads) must be imported and most probably originates in the Mediterranean.

  1. Étude de la condensation par convection forcée du R113, R152a et du R12 sur une plaque plane horizontale

    NASA Astrophysics Data System (ADS)

    Louahlia, H.; Panday, P. K.

    1996-07-01

    Forced convection condensation of pure vapour flowing between two horizontal parallel plates with the bottom plate cooled is analysed numerically. The coupled boundary layer equations for the two phases are solved using an implicite finite difference procedure. The pressure gradient, shear stress, inertia and enthalpy convection terms, and turbulence in the two phases are retained in this analysis. The laminar model and the turbulent models of Pletcher [19] and Koyama et al. [20] are compared for condensation of R113. The mean heat transfer coefficients predicted with the model of Pletcher [19] are in good agreement with the experimental results of Lu and Suryanarayana [18]. The thermal performances of R152a and R12 are also compared. For the condensation of R152a, the pressure drop is 18% smaller and the mean heat transfer coefficients are 24% higher compared to those of R12. These results are in line with the experimental work of Cheng and Tao [12]. The influence of the temperature difference and inclination of the plate on the condensate film thikness are also reported. The results of the present calculations for the condensation of R12, R152a and R113 are represented by a non-dimensional equation. La condensation en film par convection forcée est analysé numériquement pour un écoulement de vapeur pure saturée entre deux plaques planes horizontales. Le condensat se forme uniquement sur une plaque inférieure. Les équations de la couche limite appliquées dans les deux phases sont couplées et résolues par une méthode des différences finies implicite. Le gradient de pression, les contraintes tangentielles, les termes d'inertie et de convection d'enthalpie ainsi que la turbulence dans les deux phases sont pris en compte. Le modèle laminaire ainsi que les modèles de turbulence de Pletcher [19] et de Koyama et al. [20] sont comparés pour la condensation du R113. Les coefficients d'échange thermique moyens prédits avec le modèle de Pletcher, s

  2. Variation du coefficient de collage de l'argent et de l'or durant leur condensation sur film de MgO

    NASA Astrophysics Data System (ADS)

    Desrousseaux, G.; Carlan, A.; Jiang, Z.

    1993-10-01

    The incidence rate dependence of the sticking coefficient during the growth of gold (or silver) condensate on MgO film is experimentally investigated for a substrate kept at room temperature. This MgO substrate is deposited on quartz monitor by evaporation under UHV from a Knudsen cell. Then, from another cell, the flux of metal atoms impinges on the MgO film which covers the quartz. Under this flux of incident metal atoms, the changes (respectively θ and f) of the temperature and of the frequency of the quartz oscillator are then simultaneously recorded. Both continuous measurements enable us to calculate, at different times t, the sticking coefficient η (t) defined as the ration between the condensed metal rate q and the incident rate R. We use the results to plot η versus t and examine the slope of η-rise until the time t at which η (t) reaches unity. The progression of η (t) reaches unity. The progression of η (t) from zero to unity during the metal deposition is explained by assuming that the nucleation on preferred sites with capture of adatoms at the edge of stable germs is the prevailing condensation mechanism at the initial stage of the condensation. Our experimental results could be fitted better by assuming an exponential growth of the site occupation than an increase of the number density n_s(t) with (Rt)^{1/3}. On étudie expérimentalement la dépendance que peut présenter, par rapport au flux métallique incident, la progression vers l'unité du coefficient de collage. Pour cela, on suit cette progression pour l'or et l'argent condensés sur film de MgO à température proche de l'ambiante. Le substrat de MgO est déposé sur un quartz de pesée par évaporation sous ultra-vide à partir d'une cellule de Knudsen. Une autre cellule est utilsée pour déposer l'un de ces métaux sur le film de MgO couvrant le quartz. Les variations θ et f de la température et de la fréquence d'oscillations du quartz de pesée sous le flux d'atomes incidents

  3. Two new hemoglobin variants: Hb Brem-sur-Mer [beta9(A6)Ser-->Tyr] and Hb Passy [alpha81(F2)Ser-->Pro (alpha2)].

    PubMed

    Lacan, Philippe; Moreau, Mathieu; Becchi, Michel; Zanella-Cleon, Isabelle; Aubry, Martine; Louis, Jean-Jacques; Couprie, Nicole; Francina, Alain

    2005-01-01

    Two new hemoglobin (Hb) variants: Hb Brem-sur-Mer [codon 9 (TCT-->TAT); beta9(A6)Ser-->Tyr] on the first exon of the beta-globin gene and Hb Passy [codon 81 (TCC-->CCC); alpha81(F2)Ser-->Pro (alpha2)] on the second exon of the alpha2-globin gene, are described. The two variants were characterized by DNA sequencing and mass spectrometry (MS). Hematological abnormalities: microcytosis and hypochromia were found only in the carrier of Hb Passy. In the absence of an association with an alpha-thalassemic deletion or mutation, the mutation 81(F2)Pro could induce a possible alpha-thalassemia (thal).

  4. Perspective sur les ruptures d’approvisionnement de médicaments en établissement de santé de 2006 à 2010

    PubMed Central

    Bussières, Jean-François; Chiveri, Andrei; Lebel, Denis

    2011-01-01

    RÉSUMÉ Contexte: Si les ruptures d’approvisionnement de médicaments font partie de la réalité de la pratique pharmaceutique depuis plusieurs décennies, elles deviennent une préoccupation quotidienne pour les pharmaciens dans les années 2000 et dépassent les frontières de la littérature pharmaceutique. Objectif: L’objectif principal de cette étude était de quantifier le nombre de médicaments en rupture de stock par année et la durée de ces interruptions. L’objectif secondaire visait à décrire le nombre de médicaments en rupture de stock par fabricant et par classe thérapeutique. Méthode: Cette étude descriptive et rétrospective des ruptures d’approvisionnement en médicaments a porté sur l’ensemble des médicaments à contrat pour les hôpitaux des régions administratives de Montréal, de Laval et de l’Estrie, au Québec. Le nombre de ruptures de stocks, le nombre de jours de rupture de stock et leur durée moyenne par année ont été calculés par fabricant et par classe thérapeutique. De plus, la proportion de produits en rupture de stock et la proportion de jours de rupture de stocks ont été déterminées par classe thérapeutique. Les données ont été analysées à l’aide de statistiques descriptives (c.-à-d. somme, moyenne, écart-type, médiane, intervalle). Résultats: Entre le 1er janvier 2006 et le 31 août 2010 (une période de 56 mois), 2400 ruptures de stocks ont été dénombrées pour un total de 258 105 jours de rupture de stocks (durée moyenne de 108 jours, écart-type de 130 jours et intervalle de 5 à 1623 jours). Un total de 70 fabricants étaient impliqués dans la survenue de toutes les ruptures d’approvisionnement de médicaments relevées durant cette période. Cinquante pour cent (50 %) des ruptures de stocks et des jours de rupture de stocks provenaient de quatre fabricants. Les interruptions étudiées touchaient la majorité des classes thérapeutiques de médicaments disponibles sur le

  5. Embedded Gaussian unitary ensembles with U(Ω)⊗SU(r) embedding generated by random two-body interactions with SU(r) symmetry

    NASA Astrophysics Data System (ADS)

    Vyas, Manan; Kota, V. K. B.

    2012-12-01

    Following the earlier studies on embedded unitary ensembles generated by random two-body interactions [EGUE(2)] with spin SU(2) and spin-isospin SU(4) symmetries, developed is a general formulation, for deriving lower order moments of the one- and two-point correlation functions in eigenvalues, that is valid for any EGUE(2) and BEGUE(2) ("B" stands for bosons) with U(Ω)⊗SU(r) embedding and with two-body interactions preserving SU(r) symmetry. Using this formulation with r = 1, we recover the results derived by Asaga et al. [Ann. Phys. (N.Y.) 297, 344 (2002)], 10.1006/aphy.2002.6248 for spinless boson systems. Going further, new results are obtained for r = 2 (this corresponds to two species boson systems) and r = 3 (this corresponds to spin 1 boson systems).

  6. Effet de la dose d'irradiation sur la fraction tocophérolique d'huiles végétales

    NASA Astrophysics Data System (ADS)

    Chaouch, A.; El Fartah, S.; Pouliquen-Sonaglia, I.; Lesgards, G.; Raffi, J.; Trihi, M.

    1999-01-01

    Tocopherols, minor components of vegetable oils, are very important due to their high antioxydant power; we studied separation and quantification of tocopherol fraction with regard to the irradiation dose, using liquid chromatography combined with electrochemical detection. Dans les huiles végétales, les tocophérols sont des constituants mineurs très importants grâce à leur pouvoir antioxydant très élevé. Notre travail s'est porté sur la séparation et la quantification de la fraction tocophérolique et son évolution en fonction des différentes doses d'ionisation par la technique C.L.H.P. / détection électrochimique.

  7. [Length, body weight and sex of the golden Coryphaena hippurus (Perciformes: Coryphaenidae), of the littoral of Sinaloa, Nayarit and Baja California Sur, Mexico].

    PubMed

    Madrid, J V; Beltrán-Pimienta, R

    2001-01-01

    Dolphin fish population data were recorded from landings in Sinaloa, Nayarit and Baja Califonia Sur, Mexico, in 1997. Of 3,211 organisms, only 2,812 produced complete biometric data. The maximal length and weight were 192 cm and 30 kg. The three sampling sites and the climatic periods also were associated with different size (P < 0.05). The covariate analysis of weight and length relationships indicated significative differences (P < 0.05) for total data and by sex. Condition factor was higher throughout the study period in Mazatlán, and the variation was higher, in the spring. The sexual ratio was in Mazatlán constant, while there were more males in Nayarit in the fall and the spring and in Los Cabos in the spring. There may be population differences, between the central mexican Pacific Coast and the Peninsula of Baja data. PMID:12189824

  8. [Length, body weight and sex of the golden Coryphaena hippurus (Perciformes: Coryphaenidae), of the littoral of Sinaloa, Nayarit and Baja California Sur, Mexico].

    PubMed

    Madrid, J V; Beltrán-Pimienta, R

    2001-01-01

    Dolphin fish population data were recorded from landings in Sinaloa, Nayarit and Baja Califonia Sur, Mexico, in 1997. Of 3,211 organisms, only 2,812 produced complete biometric data. The maximal length and weight were 192 cm and 30 kg. The three sampling sites and the climatic periods also were associated with different size (P < 0.05). The covariate analysis of weight and length relationships indicated significative differences (P < 0.05) for total data and by sex. Condition factor was higher throughout the study period in Mazatlán, and the variation was higher, in the spring. The sexual ratio was in Mazatlán constant, while there were more males in Nayarit in the fall and the spring and in Los Cabos in the spring. There may be population differences, between the central mexican Pacific Coast and the Peninsula of Baja data.

  9. Maps showing estimated sediment yield from coastal landslides and active slope distribution along the Big Sur coast, Monterey and San Luis Obispo Counties, California

    USGS Publications Warehouse

    Hapke, Cheryl J.; Green, Krystal R.; Dallas, Kate

    2004-01-01

    The 1982-83 and 1997-98 El Ni?os brought very high precipitation to California?s central coast; this precipitation resulted in raised groundwater levels, coastal flooding, and destabilized slopes throughout the region. Large landslides in the coastal mountains of Big Sur in Monterey and San Luis Obispo Counties blocked sections of California State Route 1, closing the road for months at a time. Large landslides such as these occur frequently in the winter months along the Big Sur coast due to the steep topography and weak bedrock. A large landslide in 1983 resulted in the closure of Highway 1 for over a year to repair the road and stabilize the slope. Resulting work from the 1983 landslide cost over $7 million and generated 30 million cubic yards of debris from landslide removal and excavations to re-establish the highway along the Big Sur coast. Before establishment of the Monterey Bay National Marine Sanctuary (MBNMS) in 1992, typical road opening measures involved disposal of some landslide material and excess material generated from slope stabilization onto the seaward side of the highway. It is likely that some or most of this disposed material, either directly or indirectly through subsequent erosion, was eventually transported downslope into the ocean. In addition to the landslides that initiate above the road, natural slope failures sometimes occur on the steep slopes below the road and thus deliver material to the base of the coastal mountains where it is eroded and dispersed by waves and nearshore currents. Any coastal-slope landslide, generated through natural or anthropogenic processes, can result in sediment entering the nearshore zone. The waters offshore of the Big Sur coast are part of the MBNMS. Since it was established in 1992, landslide-disposal practices came under question for two reasons. The U.S. Code of Federal Regulations, Title 15, Section 922.132 prohibits discharging or depositing, from beyond the boundary of the Sanctuary, any material

  10. EISCAT meteor observations

    NASA Astrophysics Data System (ADS)

    Häggström, Ingemar; Pellinen-Wannberg, Asta; Westman, Assar; Vierinen, Juha; Brosch, Noah

    2010-05-01

    We present preliminary results from a 24-hour run to observe meteors conducted at EISCAT (Tromsø, Norway) on 17-18 December 2009, when no strong meteor showers were active. These pertain to the single-beam echoes detected at zenith by the Tromsø VHF and UHF systems and are compared with similar results obtained in 2008 during the peak of the Geminid meteor shower (Brosch et al. 2009). We present statistics of the echoes and concentrate, in particular, on the population of high-altitude echoes defined as being at 150-km altitude or higher, and on decelerating meteors. We also report on the character of tristatic echoes detected during the same period around 100-km altitude using the UHF receiver stations at Kiruna (Sweden) and Sodankylä (Finland), and on some low-altitude trails detected during this run. References: Brosch, N., Häggström, I., Pellinen-Wannberg, A., Westman, A. "Unusual features in high statistics radar meteor studies at EISCAT" Monthly Notices of the Royal Astronomical Society, 2009.

  11. Greenland Sea observations

    SciTech Connect

    Gudmandsen, P.; Mortensen, H.B.; Pedersen, L.T.; Skriver, H.; Minnett, P.

    1992-12-31

    ERS-1 SAR data have been acquired over the Greenland Sea and Fram Strait during two periods, the Ice Phase of three-day repeat cycle from January to March 1992 and a one-month period in the 35-day repeat cycle from 16 July to 15 August 1992. Most data became available by way of the Broadband Data Dissemination System, i.e. with a spatial resolution of about 100 m. With these data various algorithms have been tested to derive sea ice parameters such as ice extent, ice concentration and ice displacement. In the latter period data were collected to support the activities of a research vessel in the area mainly related to the large polynyas that form east and north of Greenland. The formation of polynyas could clearly be outlined but also other phenomena were observed related to the influence of wind streets and gravity waves associated with the atmospheric boundary layer. The data will have to be studied further including full-resolution data to substantiate the conclusions arrived at.

  12. [Pierre Janet observes history].

    PubMed

    Fischer-Homberger, Esther

    2014-01-01

    Janet, philosopher and physician, Freud's junior by three years, not only described traumatic dissociation and pathogenic subconscious ideas; he outlined a comprehensive system of psychology. Still, he considered his concepts to be mere linguistic tools, designed to grasp mental phenomena as precisely as possible. His prime interest was in observations - his own and those of others, whether his contemporaries at home and abroad or predecessors of all kinds. Janet never regarded himself as a historian, but his works as well as his way of thinking are most interesting from a historiographical point of view. His three-volume Médications psychologiques of 1919 contains a wealth of material about the history of psychotherapy. Furthermore, he dealt with his sources in a critical and historically reflexive manner. The later Janet considered any explanation and theory to be "inventions", more or less useful and basically open to change. By working with the notion of "narration", he described scientific statements as narratives, different from lies, fairy-tales or novels only in their claim to be verifiable. Every narration, however, is placed in a social context: narrators always wish to evoke a particular image of the real in their audience. Thus Janet established the link between scientific edifices and individual motivation, an unsettling link in terms of the history of science and certainly alien, if not positively abhorrent to Freud.

  13. Multisensor Fire Observations

    NASA Technical Reports Server (NTRS)

    Boquist, C.

    2004-01-01

    This DVD includes animations of multisensor fire observations from the following satellite sources: Landsat, GOES, TOMS, Terra, QuikSCAT, and TRMM. Some of the animations are included in multiple versions of a short video presentation on the DVD which focuses on the Hayman, Rodeo-Chediski, and Biscuit fires during the 2002 North American fire season. In one version of the presentation, MODIS, TRMM, GOES, and QuikSCAT data are incorporated into the animations of these wildfires. These data products provided rain, wind, cloud, and aerosol data on the fires, and monitored the smoke and destruction created by them. Another presentation on the DVD consists of a panel discussion, in which experts from academia, NASA, and the U.S. Forest Service answer questions on the role of NASA in fighting forest fires, the role of the Terra satellite and its instruments, including the Moderate Resolution Imaging Spectroradiometer (MODIS), in fire fighting decision making, and the role of fire in the Earth's climate. The third section of the DVD features several animations of fires over the years 2001-2003, including animations of global and North American fires, and specific fires from 2003 in California, Washington, Montana, and Arizona.

  14. Distributed Observer Network

    NASA Technical Reports Server (NTRS)

    2008-01-01

    NASA s advanced visual simulations are essential for analyses associated with life cycle planning, design, training, testing, operations, and evaluation. Kennedy Space Center, in particular, uses simulations for ground services and space exploration planning in an effort to reduce risk and costs while improving safety and performance. However, it has been difficult to circulate and share the results of simulation tools among the field centers, and distance and travel expenses have made timely collaboration even harder. In response, NASA joined with Valador Inc. to develop the Distributed Observer Network (DON), a collaborative environment that leverages game technology to bring 3-D simulations to conventional desktop and laptop computers. DON enables teams of engineers working on design and operations to view and collaborate on 3-D representations of data generated by authoritative tools. DON takes models and telemetry from these sources and, using commercial game engine technology, displays the simulation results in a 3-D visual environment. Multiple widely dispersed users, working individually or in groups, can view and analyze simulation results on desktop and laptop computers in real time.

  15. Destiny's Earth Observation Window

    NASA Technical Reports Server (NTRS)

    2002-01-01

    Astronaut Michael J. Bloomfield, STS-110 mission commander, looks through the Earth observation window in the Destiny laboratory aboard the International Space Station (ISS). The STS-110 mission prepared the ISS for future spacewalks by installing and outfitting the S0 (S-zero) truss and the Mobile Transporter. The 43-foot-long S0 Truss, weighing in at 27,000 pounds, was the first of 9 segments that will make up the Station's external framework that will eventually stretch 356 feet (109 meters), or approximately the length of a football field. This central truss segment also includes a flatcar called the Mobile Transporter and rails that will become the first 'space railroad,' which will allow the Station's robotic arm to travel up and down the finished truss for future assembly and maintenance. The completed truss structure will hold solar arrays and radiators to provide power and cooling for additional international research laboratories from Japan and Europe that will be attached to the Station. Milestones of the STS-110 mission included the first time the ISS robotic arm was used to maneuver spacewalkers around the Station and marked the first time all spacewalks were based out of the Station's Quest Airlock. It was also the first Shuttle to use three Block II Main Engines. The Space Shuttle Orbiter Atlantis, STS-110 mission, was launched April 8, 2002 and returned to Earth April 19, 2002.

  16. Benthic trophic network in the Bay of Banyuls-sur-Mer (northwest Mediterranean, France): An assessment based on stable carbon and nitrogen isotopes analysis

    NASA Astrophysics Data System (ADS)

    Carlier, Antoine; Riera, Pascal; Amouroux, Jean-Michel; Bodiou, Jean-Yves; Grémare, Antoine

    2007-03-01

    The benthic trophic network in the Bay of Banyuls-sur-Mer was studied through the carbon and nitrogen isotopic characterization of a large set of soft-bottom macrobenthic invertebrates, fishes and potential food sources. Continental inputs as well as seagrass meadows did not contribute significantly to this benthic trophic network as indicated by: (1) the difference between their δ 13C signatures (respectively -28.4‰ and -9.5‰) and those of sampled animals (between -21.0‰ and -14.6‰); and (2) their low inputs to the bay. Benthic primary consumers fed mostly on surface sediment organic matter (SSOM), which tightly interacts with suspended particulate organic matter (SPOM) and sedimenting organic matter (STOM) due to sediment resuspension. Our results also suggest the occurrence of a transfer between marine SPOM and some invertebrates (e.g. Veretillum cynomorium) and fishes (e.g. Boops boops and Spicara melanurus) through zooplankton. Moreover, the different types of primary consumers (i.e., suspension-feeders, interface-feeders, surface deposit-feeders and subsurface deposit-feeders) preferentially used distinct fractions of the heterogeneous SPOM-STOM-SSOM pool. These differences were mostly related with feeding depth and resulted in distinct isotopic signatures. Differences in the stable isotopic ratios of suspension and interface-feeders could also partly reflect the use of microphytobenthos by the later. Assuming a 15N-enrichment factor of 3.4‰ between the lower and upper ranges of two successive trophic levels, we estimated that the benthic food web of the Bay of Banyuls-sur-Mer was composed of 4 trophic levels. The comparison with our δ 13C values suggests that the whole trophic food chain is affected by continental inputs at the immediate vicinity of the Rhône River mouth even though these effects are maximal for deposit-feeding and carnivorous polychaetes.

  17. Phobos: Observed bulk properties

    NASA Astrophysics Data System (ADS)

    Pätzold, Martin; Andert, Tom; Jacobson, Robert; Rosenblatt, Pascal; Dehant, Véronique

    2014-11-01

    This work is a review of the mass determinations of the Mars moon Phobos by spacecraft close flybys, by solving for the Martian gravity field and by the analysis of secular orbit perturbations. The absolute value and accuracy is sensitive on the knowledge and accuracy of the Phobos ephemeris, of the spacecraft orbit, other perturbing forces acting on the spacecraft and the resolution of the Martian gravity field besides the measurement accuracy of the radio tracking data. The mass value and its error improved from spacecraft mission to mission or from the modern analysis of “old” tracking data but these solutions depend on the accuracy of the ephemeris at the time of observation. The mass value seems to settle within the range of GMPh=(7.11±0.09)×10-4 km3 s-2 which covers almost all mass values from close flybys and “distant” encounters within its 3-σ error (1.5%). Using the volume value determined from MEX HRSC imaging, the bulk density is (1873±31) kg m-3 (3-σ error or 1.7%), a low value which suggests that Phobos is either highly porous, is composed partially of light material or both. The determination of the gravity coefficients C20 and C22 from the Mars Express 2010 close flyby does not allow to draw conclusion on the internal structure. The large errors do not distinguish whether Phobos is homogeneous or not. In view of theories of the Phobos' origin, one possibility is that Phobos is not a captured asteroid but accreted from a debris disk in Mars orbit as a second generation solar system object.

  18. Observing Mars with MOC

    NASA Astrophysics Data System (ADS)

    Sandoval, J.; Jensen, E.; Supulver, K.; Edgett, K.; Davis, S.; Gross, W.; Zimdar, R.; Posiolova, L.; Caplinger, M.; Warren, J.; Malin, M.

    2000-12-01

    NASA's Mars Global Surveyor (MGS) has been in orbit around Mars since September 1997. The Mars Orbiter Camera (MOC) is one of 6 experiments on board MGS and has taken more than 75,000 images of the Martian surface. MOC consists of two wide angle cameras (one imaging through a 600nm red filter, the other through a 425nm blue filter), used to take daily global maps of the planet, observe weather changes, and provide context for the narrow angle images. The narrow angle camera -- an f/10 3.5m focal length telescope -- is used to acquire high resolution images of specific targets and randomly sample other terrain. MOC primarily looks nadir, but spacecraft slews can be commanded, for example, to examine landing sites and to measure focus performance by imaging stars. MOC is operated by Malin Space Science Systems, Inc., from its facilities in San Diego, CA. A six person operations staff is responsible for selecting targets, commanding the camera, retrieving data from Project computers at the Jet Propulsion Laboratory, checking quality, and archiving the raw data with NASA's Planetary Data System. Following a six-month validation process, the data are made publicly available on the World Wide Web. Specific images of interest are highlighted in media-related web releases. We present an overview of MOC and its operation, with emphasis on the archiving process and details of the camera's design and implementation. We also include some recent images and examples of the active environment of Mars, such as the seasonal regression of the polar caps and dust storms.

  19. CCD Camera Observations

    NASA Astrophysics Data System (ADS)

    Buchheim, Bob; Argyle, R. W.

    One night late in 1918, astronomer William Milburn, observing the region of Cassiopeia from Reverend T.H.E.C. Espin's observatory in Tow Law (England), discovered a hitherto unrecorded double star (Wright 1993). He reported it to Rev. Espin, who measured the pair using his 24-in. reflector: the fainter star was 6.0 arcsec from the primary, at position angle 162.4 ^{circ } (i.e. the fainter star was south-by-southeast from the primary) (Espin 1919). Some time later, it was recognized that the astrograph of the Vatican Observatory had taken an image of the same star-field a dozen years earlier, in late 1906. At that earlier epoch, the fainter star had been separated from the brighter one by only 4.8 arcsec, at position angle 186.2 ^{circ } (i.e. almost due south). Were these stars a binary pair, or were they just two unrelated stars sailing past each other? Some additional measurements might have begun to answer this question. If the secondary star was following a curved path, that would be a clue of orbital motion; if it followed a straight-line path, that would be a clue that these are just two stars passing in the night. Unfortunately, nobody took the trouble to re-examine this pair for almost a century, until the 2MASS astrometric/photometric survey recorded it in late 1998. After almost another decade, this amateur astronomer took some CCD images of the field in 2007, and added another data point on the star's trajectory, as shown in Fig. 15.1.

  20. Observation as an Assessment Tool.

    ERIC Educational Resources Information Center

    Nickell, Pat; Wilson, Angene

    1999-01-01

    Considers the use of observation in the classroom as a means of student assessment. Focuses on developing an observation instrument, the scoring criteria, and using progress-based rankings rather than static rankings. Provides an example teacher observation form. (CMK)

  1. Modern Observational Techniques for Comets

    NASA Technical Reports Server (NTRS)

    Brandt, J. C. (Editor); Greenberg, J. M. (Editor); Donn, B. (Editor); Rahe, J. (Editor)

    1981-01-01

    Techniques are discussed in the following areas: astrometry, photometry, infrared observations, radio observations, spectroscopy, imaging of coma and tail, image processing of observation. The determination of the chemical composition and physical structure of comets is highlighted.

  2. Earth observing scanning polarimeter

    NASA Technical Reports Server (NTRS)

    Travis, Larry

    1993-01-01

    Climate forcing by tropospheric aerosols is receiving increased attention because of the realization that the climate effects may be large, while our knowledge of global aerosol characteristics and temporal changes is very poor. Tropospheric aerosols cause a direct radiative forcing due simply to their scattering and absorption of solar radiation, as well as an indirect effect as cloud condensation nuclei which can modify the shortwave reflectivity of clouds. Sulfate aerosols tend to increase planetary albedo through both the direct and indirect effects; a cooling due to anthropogenic sulfate aerosols has been estimated of order 1 W/sq m, noting that this is similar in magnitude to the present anthropogenic greenhouse gas warming. Other aerosols, including those from biomass burning and wind-blown desert dust are also of potential climatic importance. At present, the only global monitoring of tropospheric aerosols is a NOAA operational product, aerosol optical thickness, obtained using channel-1 (0.58-0.68 mu m) radiances from the AVHRR. With this single channel radiance data, one must use an approach which is based on the inferred excess of reflected radiance owing to scattering by the aerosols over that expected from theoretical calculations. This approach is suited only for situations where the surface has a low albedo that is well known a priori. Thus, the NOAA operational product is restricted to coverage over the ocean at AVHRR scan angles well away from sun glint, and aerosol changes are subject to confusion with changes caused by either optically thin or subpixel clouds. Because optically thin aerosols have only a small effect on the radiance, accurate measurements for optical thickness less than 0.1 (which is a typical background level) are precluded. Moreover, some of the largest and most important aerosol changes are expected over land. The Earth Observing Scanning Polarimeter (EOSP) instrument, based upon design heritage and analysis techniques

  3. Geometrically constrained observability. [control theory

    NASA Technical Reports Server (NTRS)

    Brammer, R. F.

    1974-01-01

    This paper deals with observed processes in situations in which observations are available only when the state vector lies in certain regions. For linear autonomous observed processes, necessary and sufficient conditions are obtained for half-space observation regions. These results are shown to contain a theorem dual to a controllability result proved by the author for a linear autonomous control system whose control restraint set does not contain the origin as an interior point. Observability results relating to continuous observation systems and sampled data systems are presented, and an example of observing the state of an electrical network is given.

  4. Lignes directrices canadiennes sur l’utilisation sécuritaire et efficace des opioïdes pour la douleur chronique non cancéreuse

    PubMed Central

    Kahan, Meldon; Wilson, Lynn; Mailis-Gagnon, Angela; Srivastava, Anita

    2011-01-01

    Résumé Objectif Présenter aux médecins de famille un résumé clinique pratique sur la prescription d’opioïdes à des populations particulières en se fondant sur les recommandations faites dans les lignes directrices canadiennes sur l’utilisation sécuritaire et efficace des opioïdes pour la douleur chronique non cancéreuse. Qualité des données Pour produire les lignes directrices, les chercheurs ont effectué une synthèse critique de la littérature médicale en insistant plus précisément sur les études de l’efficacité et de la sécurité des opioïdes dans des populations particulières. Message principal Les médecins de famille peuvent atténuer les risques de surdose, de sédation, d’usage abusif et de dépendance grâce à des stratégies adaptées à l’âge et à l’état de santé des patients. Dans le cas de patients à risque de dépendance, on devrait réserver les opioïdes aux douleurs nociceptives ou neuropathiques bien définies qui n’ont pas répondu aux traitements de première intention. Il faut procéder lentement au titrage des opioïdes, avec des dispensations fréquentes et une étroite surveillance pour dépister tout signe d’usage abusif. Une dépendance aux opioïdes suspectée est prise en charge au moyen d’une thérapie structurée aux opioïdes, d’un traitement à la méthadone ou à la buprénorphine ou encore d’un traitement fondé sur l’abstinence. Les patients souffrant de troubles de l’humeur ou d’anxiété ont tendance à avoir une réponse analgésique atténuée aux opioïdes, sont à risque plus élevé d’usage abusif et prennent souvent des sédatifs qui interagissent défavorablement avec les opioïdes. Il faut prendre des précautions semblables à celles utilisées avec d’autres patients à risque élevé. Il faut faire un sevrage progressif si la douleur du patient demeure sévère même avec un essai adéquat de thérapie aux opioïdes. Chez les personnes âgées, la s

  5. Near-Earth asteroids: Observer alert network and physical observations

    NASA Technical Reports Server (NTRS)

    Davis, Donald R.; Chapman, Clark R.

    1992-01-01

    This project strives to obtain physical observations on newly discovered Near-Earth Objects (NEO's) in order to provide fundamental data needed to assess the resources available in the population. The goal is acquiring data on all objects brighter than magnitude V= 17.0. To accomplish this, an electronic mail alert and observer information service that informs observers around the world as to the status of physical observations on currently observable NEO's was established. Such data is also acquired ourselves through a cooperative program with European colleagues that uses telescopes on La Palma to obtain spectra of NEO's and through observations made from a local telescope on Tumamoc Hill. This latter telescope has the advantage that large amounts of observing time are available, so that whenever a new NEO's discovered, we can be assured of getting time to observe it.

  6. Workshop on Mars Telescopic Observations

    NASA Technical Reports Server (NTRS)

    Bell, J. F., III (Editor); Moersch, J. E. (Editor)

    1995-01-01

    The Mars Telescopic Observations Workshop, held August 14-15, 1995, at Cornell University in Ithaca, New York, was organized and planned with two primary goals in mind: The first goal was to facilitate discussions among and between amateur and professional observers and to create a workshop environment fostering collaborations and comparisons within the Mars observing community. The second goal was to explore the role of continuing telescopic observations of Mars in the upcoming era of increased spacecraft exploration. The 24 papers presented at the workshop described the current NASA plans for Mars exploration over the next decade, current and recent Mars research being performed by professional astronomers, and current and past Mars observations being performed by amateur observers and observing associations. The workshop was divided into short topical sessions concentrating on programmatic overviews, groundbased support of upcoming spacecraft experiments, atmospheric observations, surface observations, modeling and numerical studies, and contributions from amateur astronomers.

  7. Observational Learning and the Effects of Model-Observer Similarity.

    ERIC Educational Resources Information Center

    Braaksma, Martine A. H.; Rijlaarsdam, Gert; van den Bergh, Huub

    2002-01-01

    This study examined the effects of similarity in competence between model and observer on the effectiveness of observational learning in argumentative writing. Results are consistent with the similarity hypothesis: weak learners learn more from focusing their observations on weak models, whereas better learners learn more from focusing on good…

  8. Impact of HIV-1 genetic diversity on plasma HIV-1 RNA Quantification: usefulness of the Agence Nationale de Recherches sur le SIDA second-generation long terminal repeat-based real-time reverse transcriptase polymerase chain reaction test.

    PubMed

    Rouet, François; Chaix, Marie-Laure; Nerrienet, Eric; Ngo-Giang-Huong, Nicole; Plantier, Jean-Christophe; Burgard, Marianne; Peeters, Martine; Damond, Florence; Ekouevi, Didier Koumavi; Msellati, Philippe; Ferradini, Laurent; Rukobo, Sandra; Maréchal, Valérie; Schvachsa, Nilda; Wakrim, Lahcen; Rafalimanana, Christian; Rakotoambinina, Benjamin; Viard, Jean-Paul; Seigneurin, Jean-Marie; Rouzioux, Christine

    2007-08-01

    The high genetic diversity of HIV-1 has a major impact on the quantification of plasma HIV-1 RNA, representing an increasingly difficult challenge. A total of 898 plasma specimens positive for HIV-1 RNA by commercial assays (Amplicor v1.5; Roche Diagnostic Systems, Alameda, CA or Versant v3.0; Bayer Diagnostics, Emeryville, CA) were tested using the Agence Nationale de Recherches sur le SIDA second-generation (G2) real-time reverse transcriptase polymerase chain reaction (RT-PCR) test: 518 samples containing HIV-1 of known subtype, including 88 from 2 subtype panels and 430 harboring B (n = 266) and non-B (n = 164) group M HIV-1 subtypes from patients followed up in 2002 through 2005 at Necker Hospital (Paris, France), and 380 samples from 10 different countries (Argentina, Cambodia, Cameroon, Central African Republic, France, Ivory Coast, Madagascar, Morocco, Thailand, and Zimbabwe). HIV-1 RNA values obtained by G2 real-time PCR were highly correlated with those obtained by the Amplicor v1.5 for B and non-B subtypes (R = 0.892 and 0.892, respectively) and for samples from diverse countries (R = 0.867 and 0.893 for real-time PCR vs. Amplicor v1.5 and real-time PCR vs. Versant v3.0, respectively). Approximately 30% of specimens harboring non-B subtypes were underquantified by at least -0.51 log10 in Amplicor v1.5 versus 5% underquantified in G2 real-time PCR. Discrepant results were also obtained with subtype B samples (14% underquantified by Amplicor v1.5 vs. 7% by G2 real-time PCR). Similar percentages were observed when comparing results obtained with the G2 real-time PCR assay with those obtained using the Versant assay. Addressing HIV-1 diversity, continual monitoring of HIV-1 RNA assays, together with molecular epidemiology studies, is required to improve the accuracy of all HIV RNA assays.

  9. Lignes directrices canadiennes sur l’utilisation sécuritaire et efficace des opioïdes pour la douleur chronique non cancéreuse

    PubMed Central

    Kahan, Meldon; Mailis-Gagnon, Angela; Wilson, Lynn; Srivastava, Anita

    2011-01-01

    Résumé Objectif Présenter aux médecins de famille un résumé clinique pratique des lignes directrices canadiennes sur l’utilisation sécuritaire et efficace des opioïdes pour la douleur chronique non cancéreuse, produites par le National Opioid Use Guideline Group. Qualité des données Pour produire les lignes directrices, les chercheurs ont effectué une synthèse critique de la littérature médicale sur l’efficacité et l’innocuité des opioïdes pour la douleur chronique non cancéreuse et ont rédigé une série de recommandations. Un panel de 49 cliniciens experts de toutes les régions du Canada ont passé en revue l’ébauche et ont atteint un consensus sur 24 recommandations. Message principal Il est recommandé de faire un dépistage du risque de dépendance avant de prescrire des opioïdes. On recommande des opioïdes faibles (codéine et tramadol) pour une douleur de légère à modérée qui n’a pas répondu aux traitements de première intention. On peut essayer l’oxycodone, l’hydromorphone et la morphine chez les patients qui n’ont pas eu de soulagement avec des opioïdes plus faibles. Une faible dose initiale et une lente hausse du titrage sont recommandées, ainsi qu’une étroite surveillance du patient qu’on a d’abord renseigné. Les médecins doivent surveiller l’apparition de complications comme l’apnée du sommeil. La dose optimale est celle qui améliore le fonctionnement ou atténue les cotes d’évaluation de la douleur d’au moins 30 %. Pour la grande majorité des patients, la dose optimale sera bien en deçà de l’équivalent de 200 mg de morphine par jour. On recommande le sevrage progressif pour les patients qui n’ont pas répondu à un essai d’opioïdes adéquat. Conclusion Les opioïdes jouent un rôle important dans la prise en charge de la douleur chronique non cancéreuse, mais il faut en prescrire avec prudence pour limiter les dommages potentiels. Les nouvelles lignes directrices

  10. Quatrième conférence consensuelle sur le diagnostic et le traitement de la démence

    PubMed Central

    Moore, Ainsley; Patterson, Christopher; Lee, Linda; Vedel, Isabelle; Bergman, Howard

    2014-01-01

    Résumé Objectif Revoir les stratégies diagnostiques de la maladie d’Alzheimer, actualiser les recommandations concernant le traitement des symptômes de démence et proposer une approche thérapeutique à la démence d’apparition précoce et d’évolution rapide. Composition du comité Des spécialistes et des délégués de diverses régions du Canada et représentant diverses disciplines pertinentes ont discuté et se sont mis d’accord sur les révisions à apporter aux lignes directrices de 2006. Méthodologie On a eu recours au système GRADE (grading of recommendations, assessment, development, and evaluation) pour évaluer le consensus concernant les recommandations, lequel était défini comme suit : lorsque 80 % ou plus des participants ont voté en faveur de la recommandation. La cote des données probantes est rapportée lorsque cela est possible. Rapport important pour les médecins de famille, malgré les progrès effectués dans les domaines des biomarqueurs liquidiens et de la neuro-imagerie, le diagnostic de démence au Canada demeure fondamentalement clinique. De nouveaux critères cliniques essentiels de diagnostic de la maladie d’Alzheimer en reconnaissent dorénavant les formes moins fréquentes et non amnestiques. La démence précoce, une affection rare, mais importante, devrait inciter les médecins à aiguiller les patients vers un spécialiste ayant accès à des conseillers en génétique. La démence d’évolution rapide, mal définie dans la littérature, faciliterait le dépistage de cette affection rare, mais importante. Les inhibiteurs de la cholinestérase sont maintenant indiqués pour le traitement d’affections autres que la maladie d’Alzheimer. Des lignes directrices concernant l’arrêt du traitement, lesquelles n’existaient pas auparavant, sont également apparues. De nouvelles données probantes sur le recours à la mémantine, aux antidépresseurs et à d’autres agents psychotropes dans le traitement de la

  11. How to observe with GTC

    NASA Astrophysics Data System (ADS)

    Villamariz, M. R.

    2007-06-01

    We present here the outline of the process that any potential GTC observer will need to follow in order to perform their observations. Depending on which of the members of the GTC community the observer belongs to, the details of the different steps and timeline of the process will differ slightly, but in general it will be as follows: first the (Phase I) observing proposal will have to be prepared and submitted to the corresponding Time Allocation Committee. If the proposal is awarded time, then the observer will have to prepare and submit the (Phase II) observing programme to GTC, that will asses it and iterate with the observer if necessary until the observing programme is ready to enter our system. If the observer got time in the classical visiting mode, he/she will have to come in the scheduled dates to perform the observations together with the assigned support astronomer, and if the observations were asked for in service mode, we will schedule and perform them. The result of the process will be both the raw and validated data that will be delivered to the observer and kept in our archive where the rest of the community will be able to access them once the year of exclusivity of the observer has expired.

  12. Si vous pensez que c'est juste un mal de jambe… détrompez-vous: ce que les leaders en santé doivent savoir sur la maladie artérielle périphérique.

    PubMed

    Papia, Giuseppe; Mayer, Perry; Kelton, David; Queen, Douglas; Elliott, James A; Kuhnke, Janet L

    2015-11-01

    Environ 800 000 Canadiens ont une maladie artérielle périphérique (MAP), une cause majeure d'amputation. Pourtant, le public et les cliniciens connaissent très peu cette maladie. Le présent article traite de la campagne de sensibilisation Si vous pensez que c'est juste un mal de jambe… détrompez-vous que l'Association canadienne du soin des plaies a lancée pour contrer cette tendance. Il porte également sur les facteurs de risque et le dépistage de la MAP, son lien avec le diabète, son traitement et ses soins, ses innovations en matière de soins de la MAP et la nécessité de faire preuve de leadership sur le plan des politiques. PMID:26487733

  13. Observations of FK Comae stars

    NASA Technical Reports Server (NTRS)

    Bopp, B. W.

    1981-01-01

    Observations on the FK Comae stars are described. FK Com, UZ Lib and HD 199178 are compared and related as a group of stars. The crucial observational tests of the proposed evolutionary status of these stars are noted.

  14. An Experience in Participant Observation

    ERIC Educational Resources Information Center

    Jackson, Bettie S.

    1975-01-01

    The conflict in participant observation is between the nurse as observer and the nurse as care provider. For nursing, the gains are descriptive, theory-generating data; for the nurse researcher, a heightened awareness of the human condition. (Author)

  15. Skylab observations of Comet Kohoutek

    NASA Technical Reports Server (NTRS)

    Snoddy, W. C.; Gary, G. A.

    1974-01-01

    This paper summarizes the special operational procedures developed to observe the Comet Kohoutek from Skylab and the scientific results from these observations. Emphasis is placed on results from Skylab experiments S052, White Light Coronagraph; S201, Far UV Electronographic Camera; S233, Kohoutek Photometric Photography; S019, UV Stellar Astronomy; S183, Ultraviolet Panorama Telescope; and S082B, Ultraviolet Spectrography. Visual observations by the astronaut crew and the significance of these observations are discussed.

  16. Structure and geomorphology of the "big bend" in the Hosgri-San Gregorio fault system, offshore of Big Sur, central California

    NASA Astrophysics Data System (ADS)

    Johnson, S. Y.; Watt, J. T.; Hartwell, S. R.; Kluesner, J. W.; Dartnell, P.

    2015-12-01

    The right-lateral Hosgri-San Gregorio fault system extends mainly offshore for about 400 km along the central California coast and is a major structure in the distributed transform margin of western North America. We recently mapped a poorly known 64-km-long section of the Hosgri fault offshore Big Sur between Ragged Point and Pfieffer Point using high-resolution bathymetry, tightly spaced single-channel seismic-reflection and coincident marine magnetic profiles, and reprocessed industry multichannel seismic-reflection data. Regionally, this part of the Hosgri-San Gregorio fault system has a markedly more westerly trend (by 10° to 15°) than parts farther north and south, and thus represents a transpressional "big bend." Through this "big bend," the fault zone is never more than 6 km from the shoreline and is a primary control on the dramatic coastal geomorphology that includes high coastal cliffs, a narrow (2- to 8-km-wide) continental shelf, a sharp shelfbreak, and a steep (as much as 17°) continental slope incised by submarine canyons and gullies. Depth-converted industry seismic data suggest that the Hosgri fault dips steeply to the northeast and forms the eastern boundary of the asymmetric (deeper to the east) Sur Basin. Structural relief on Franciscan basement across the Hosgri fault is about 2.8 km. Locally, we recognize five discrete "sections" of the Hosgri fault based on fault trend, shallow structure (e.g., disruption of young sediments), seafloor geomorphology, and coincidence with high-amplitude magnetic anomalies sourced by ultramafic rocks in the Franciscan Complex. From south to north, section lengths and trends are as follows: (1) 17 km, 312°; (2) 10 km, 322°; (3)13 km, 317°; (4) 3 km, 329°; (5) 21 km, 318°. Through these sections, the Hosgri surface trace includes several right steps that vary from a few hundred meters to about 1 km wide, none wide enough to provide a barrier to continuous earthquake rupture.

  17. Etiologies et pronostic des occlusions intestinales aigues mécaniques à l’Hôpital National de Zinder: étude transversale sur 171 patients

    PubMed Central

    Adamou, Harissou; Magagi, Ibrahim Amadou; Habou, Oumarou; Magagi, Amadou; Maazou, Halidou; Adamou, Mansour; Harouna, Yacouba

    2016-01-01

    L’occlusion intestinale aigue (OIA) mécanique, représente l’une des pathologies les plus fréquentes en chirurgie digestive d’urgence. L’objectif de cette étude était de décrire les aspects étiologiques et pronostiques des occlusions intestinales aigues mécaniques à l’Hôpital National de Zinder (HNZ), Niger. Il s’agissait d’une étude transversale sur 24 mois (Janvier 2013 à Décembre 2014) ayant inclus tous les patients opérés pour OIA. Les occlusions intestinales mécaniques représentaient 24,50% (n=171) des urgences chirurgicales digestives (n=622). L’âge médian était à 25 ans (extrêmes: 1 jour et 95 ans). Le sexe ratio était à 3,5 en faveur des hommes. Les enfants représentaient 38,60% (n=66). Le siège de l’obstacle était sur le grêle dans 60,82% (n=104), colique dans 21,63%(n=37) et mixte dans 17,54% (n=30). Le mécanisme par strangulation constituait 88,89% (n=152) dont les hernies étranglées avec 49,70% (n=85) et les invaginations intestinales aigues avec 19,88% (n=34) des patients. Les malformations ano-rectales et les tumeurs constituaient les principales étiologies par obstruction avec respectivement 7,02% (n=12) et 3,51% (n=6). Une résection intestinale était faite dans 52 cas (30,41%). Les complications septiques prédominaient (n=39/53), dont la suppuration pariétale (n=23). Le séjour moyen était de 7,82 jours. La mortalité globale était 11,70% (n=20). Celle-ci était corrélée statistiquement à la nécrose intestinale (p=0,01) et au retard d’admission (p=0,04). Les étiologies des OIA sont multiples et dominées par les hernies étranglées. La morbi-mortalité élevée qu’elles entrainent pourrait être évitée par la prise en charge précoce avant l’installation d’une nécrose intestinale.

  18. Suivi prospectif sur 5 ans des tentatives de suicide en population clinique dans la région de Fès, Maroc

    PubMed Central

    Aarab, Chadya; Elghazouani, Fatima; Aalouane, Rachid; Rammouz, Ismail

    2014-01-01

    Au Maroc, les tentatives de suicide (TS) demeurent un sujet mal évalué à cause de considérations socioculturelles et l'absence d'approche longitudinale. L'objectif principal était d’évaluer le devenir des suicidants après 5ans au centre universitaire psychiatrique de Fès, les objectifs secondaires étaient l'estimation de la prévalence des TS, préciser les étiologies les plus fréquentes, et établir une corrélation entre les paramètres sociodémographiques, cliniques et évolutifs. Etude prospective à visée transversale et longitudinale, incluant les suicidants vus à l'hôpital psychiatrique de Fès, avec un suivi longitudinal sur 5ans. L’évaluation a été faite par un hétéro-questionnaire et le Mini International Neuropsychiatric Interview (MINI) cherchant le trouble psychiatrique sous jacent. On a recruté 105 patients suicidants, 62% des femmes, l’âge moyen est de 29,23ans. La prévalence des tentatives de suicide est de 3% sur l'ensemble des consultants à l’établissement. Les troubles de l'humeur, psychotiques et de personnalité ont occupé respectivement 37,6%, 27,7%, et 25,7% des cas. La récidive suicidaire a été notée chez 54% des patients, était significativement corrélée à la vie solitaire (P: 0,039) et à la présence d'antécédents familiaux de TS (P: 0,046). L'utilisation de moyens violents était significativement fréquente chez les patients psychotiques. Après 5ans, 32 patients ont répondu à notre appel. Le taux de récidive était de 15%. On a noté trois cas de décès dont deux suicides confirmés. Les résultats confirment les données de la littérature scientifique avec certaines particularités cliniques et évolutives. PMID:25478042

  19. Qualité des certificats de coups et blessures volontaires sur adultes à Dakar et Diourbel, Sénégal

    PubMed Central

    Soumah, Mohamed Maniboliot; Ngwa, Hugues Elie Elame; Ndiaye, Mor; Sow, Mamadou Lamine

    2011-01-01

    Introduction Le certificat médical est une attestation écrite, destinée à constater un fait d'ordre médical. L'intérêt de cette étude résultait de la fréquence du contentieux entre représentants de la loi et médecins à propos des certificats médicaux descriptifs de coups et blessures volontaires. Les objectifs étaient d’étudier les critères d’établissement des certificats médicaux dans les cas de coups et blessures volontaires, d’évaluer la qualité des certificats médicaux dans les procédures judiciaires dans les régions de Dakar et de Diourbel, d'apprécier l’évaluation de l'Incapacité Totale de Travail fixée par les médecins et leurs implications judiciaires. Méthodes Nous avons étudié 201 certificats descriptifs de constatation de coups et blessures volontaires. L'incapacité totale de travail (ITT) au sens pénal a été revue par un médecin légiste. Les données recueillies ont été saisies et analysées par logiciel Epi Data version 3.1 et Epi Info 6.04. Résultats Le nom et les prénoms du médecin étaient mentionnés sur les 201 certificats. Sur les 201 certificats étudiés, 170 mentionnaient les faits rapportés par la victime. En proposant de manière comparative pour chacune des ITT fixées par le médecin, une ITT pénale, nous trouvions des erreurs entre ITT pénale et ITT civile (dans 95% des cas). Conclusion Les certificats médicaux délivrés sont incomplets. Les recommandations concernent la création d'unités médico-judiciaires et de centres d'accueil des victimes d'agression. PMID:22384305

  20. Polymorphisme de l'apolipoprotéine E dans la population du nord du Maroc: fréquence et influence sur les paramètres lipidiques

    PubMed Central

    Benyahya, Fatiha; Barakat, Amina; Ghailani, Naima; Bennani, Mohcine

    2013-01-01

    Introduction L'objectif de ce travail est de déterminer les fréquences alléliques et génotypiques des sites polymorphes situés dans le gène de l'apolipoprotéine E (apo E) ainsi que leur impact sur les paramètres cliniques et lipidiques dans un échantillon de la population du nord du Maroc cliniquement diagnostiqué ADH. Méthodes Le génotype de l'apo E a été analysé par séquençage direct chez 46 patients cliniquement diagnostiqués ADH selon les critères standards. Résultats Les fréquences des allèles epsilon 3, epsilon 2 et epsilon 4 ont été respectivement 78.3%, 2.2% et 19.6%. La fréquence de l'allèle epsilon 4 est très élevée chez la population du nord du Maroc en comparaison avec les populations des autres régions marocaines. Elle est similaire à celle rapportée dans les pays de l'Europe du nord. Les taux du cholestérol total, du cholestérol LDL ainsi que la présence des xanthomes et les maladies cardiovasculaires ne différent pas entre les génotypes de l'apoE. En revanche, les résultats ont montré une influence de l'allèle epsilon4 sur le taux des triglycérides chez les sujets obèses. Conclusion Le génotype de l'apoE ne peut expliquer le phénotype clinique et biochimique présenté par des patients du Nord du Maroc cliniquement diagnostiqués ADH. PMID:24396563

  1. General characteristics of the diet of Trachinotus paitensis (Teleostei: Carangidae) from San Ignacio Lagoon, Baja California Sur, Mexico.

    PubMed

    Cruz Escalona, V H; Abitia Cárdenas, L A

    2004-03-01

    The food habits of Trachinotus paitensis, in San Ignacio Lagoon B.C.S., Mexico, were investigated. We observed that T. paitensis is carnivorous, feeding mainly on benthic invertebrates (the gastropods Anachis spp., Bittium spp., and the crustacean larvae). We concluded that T. paitensis is an opportunist predator that impacts mainly on epibenthic invertebrates.

  2. Movement Processes as Observable Behavior.

    ERIC Educational Resources Information Center

    Harrington, Wilma M.

    The operations for achieving skill in motor performance are perceiving, patterning, adapting, refining, varying, improvising, and composing. These operations are readily observable in physical education classes. An observation record containing the seven catagories was used to classify teacher feedback to students. The teachers observed were…

  3. Observability in dynamic evolutionary models.

    PubMed

    López, I; Gámez, M; Carreño, R

    2004-02-01

    In the paper observability problems are considered in basic dynamic evolutionary models for sexual and asexual populations. Observability means that from the (partial) knowledge of certain phenotypic characteristics the whole evolutionary process can be uniquely recovered. Sufficient conditions are given to guarantee observability for both sexual and asexual populations near an evolutionarily stable state.

  4. Babylonian Observational and Predictive Astronomy

    NASA Astrophysics Data System (ADS)

    Steele, John M.

    Babylonian astronomers during the last seven and a half centuries BC kept systematic records of night-by-night observations of a range of astronomical phenomena. From these observations, lunar and planetary cycles were identified which were used to make predictions of future astronomical phenomena from previous observations.

  5. Doppler observations of solar rotation

    NASA Technical Reports Server (NTRS)

    Scherrer, P. H.; Wilcox, J. M.

    1980-01-01

    Daily observations of the photospheric equatorial rotation rate using the Doppler effect are made at the Stanford Solar Observatory. These observations show no variations in the rotation rate that exceed the observational error of about 1%. The average rotation rate is indistinguishable from that of sunspots and large-scale magnetic field structures.

  6. Doppler observations of solar rotation

    NASA Technical Reports Server (NTRS)

    Scherrer, P. H.

    1980-01-01

    Daily observations of the photospheric equatorial rotation rate using the Doppler effect mode at the Sanford Solar Observatory are presented. These observations show no variations in the rotation rate that exceed the observational error of about one percent. The average rotation rate is indistinguishable from that of sunspots and large scale magnetic field structures.

  7. astroplan: Observation Planning for Astronomers

    NASA Astrophysics Data System (ADS)

    Morris, Brett

    2016-03-01

    Astroplan is an observation planning package for astronomers. It is an astropy-affiliated package which began as a Google Summer of Code project. Astroplan facilitates convenient calculation of common observational quantities, like target altitudes and azimuths, airmasses, and rise/set times. Astroplan also computes when targets are observable given various extensible observing constraints, for example: within a range of airmasses or altitudes, or at a given separation from the Moon. Astroplan is taught in the undergraduate programming for astronomy class, and enables observational Pre- MAP projects at the University of Washington. In the near future, we plan to implement scheduling capabilities in astroplan on top of the constraints framework.

  8. State observer for synchronous motors

    DOEpatents

    Lang, Jeffrey H.

    1994-03-22

    A state observer driven by measurements of phase voltages and currents for estimating the angular orientation of a rotor of a synchronous motor such as a variable reluctance motor (VRM). Phase voltages and currents are detected and serve as inputs to a state observer. The state observer includes a mathematical model of the electromechanical operation of the synchronous motor. The characteristics of the state observer are selected so that the observer estimates converge to the actual rotor angular orientation and velocity, winding phase flux linkages or currents.

  9. The structure of robust observers

    NASA Technical Reports Server (NTRS)

    Bhattacharyya, S. P.

    1975-01-01

    Conventional observers for linear time-invariant systems are shown to be structurally inadequate from a sensitivity standpoint. It is proved that if a linear dynamic system is to provide observer action despite arbitrary small perturbations in a specified subset of its parameters, it must: (1) be a closed loop system, be driven by the observer error, (2) possess redundancy, the observer must be generating, implicitly or explicitly, at least one linear combination of states that is already contained in the measurements, and (3) contain a perturbation-free model of the portion of the system observable from the external input to the observer. The procedure for design of robust observers possessing the above structural features is established and discussed.

  10. Neural mechanisms of observational learning

    PubMed Central

    Burke, Christopher J.; Tobler, Philippe N.; Baddeley, Michelle; Schultz, Wolfram

    2010-01-01

    Individuals can learn by interacting with the environment and experiencing a difference between predicted and obtained outcomes (prediction error). However, many species also learn by observing the actions and outcomes of others. In contrast to individual learning, observational learning cannot be based on directly experienced outcome prediction errors. Accordingly, the behavioral and neural mechanisms of learning through observation remain elusive. Here we propose that human observational learning can be explained by two previously uncharacterized forms of prediction error, observational action prediction errors (the actual minus the predicted choice of others) and observational outcome prediction errors (the actual minus predicted outcome received by others). In a functional MRI experiment, we found that brain activity in the dorsolateral prefrontal cortex and the ventromedial prefrontal cortex respectively corresponded to these two distinct observational learning signals. PMID:20660717

  11. Neural mechanisms of observational learning.

    PubMed

    Burke, Christopher J; Tobler, Philippe N; Baddeley, Michelle; Schultz, Wolfram

    2010-08-10

    Individuals can learn by interacting with the environment and experiencing a difference between predicted and obtained outcomes (prediction error). However, many species also learn by observing the actions and outcomes of others. In contrast to individual learning, observational learning cannot be based on directly experienced outcome prediction errors. Accordingly, the behavioral and neural mechanisms of learning through observation remain elusive. Here we propose that human observational learning can be explained by two previously uncharacterized forms of prediction error, observational action prediction errors (the actual minus the predicted choice of others) and observational outcome prediction errors (the actual minus predicted outcome received by others). In a functional MRI experiment, we found that brain activity in the dorsolateral prefrontal cortex and the ventromedial prefrontal cortex respectively corresponded to these two distinct observational learning signals.

  12. Neurocysticercose révélée par une épilepsie réfractaire: à propos d'une observation

    PubMed Central

    Bugeme, Marcellin; Mukuku, Olivier

    2015-01-01

    Nous rapportons une observation de neurocysticercose parenchymateuse chez un homme de 38 ans, consommant régulièrement la viande de porc, qui a présenté une épilepsie réfractaire. Le diagnostic de NCC était basé sur la présence de lésions kystiques montrant le scolex sur les images du scanner cérébrale, la présence de signes cliniques évocateurs de NCC (épilepsie faite des crises convulsives focales évoluant vers des crises bilatérales), la réponse clinique au traitement à l'albendazole et le fait que notre patient vit dans une zone reconnue endémique à la cysticercose. Après un traitement fait d'albendazole et de prednisolone, l’évolution est marquée par la disparition complète des crises épileptiques. PMID:26090052

  13. Biomagnification of mercury and its antagonistic interaction with selenium in yellowfin tuna Thunnus albacares in the trophic web of Baja California Sur, Mexico.

    PubMed

    Ordiano-Flores, Alfredo; Rosíles-Martínez, Rene; Galván-Magaña, Felipe

    2012-12-01

    Mercury and selenium concentrations were determined in muscle of 37 yellowfin tuna (Thunnus albacares) captured aboard of Mexican purse-seiners boats off western coast of Baja California Sur, between Punta Eugenia and Cabo Falso, from October to December 2006. Also, its prey (mainly, jumbo squid Dosidicus gigas and pelagic red crab Pleuroncodes planipes) were analyzed from the stomach contents. All the mercury values obtained were lower that mercury content recommended by standard legal limits for seafood adopted by Mexican norms (typically 0.5-1.0μg g(-1)). Mercury concentrations vary between 0.06 and 0.51μg g(-1) in yellowfin tuna, and from 0.01 to 0.20μg g(-1) in its prey, suggesting that mercury can accumulate in prey tissues and that of their predator. Biomagnification factors (BMF) between predator-prey associations were calculated. The BMFs were >1, indicating that mercury biomagnifies along the food web of yellowfin tuna. In all species studied there was a molar excess of selenium over mercury. The rank order of mean selenium/mercury molar ratios was for pufferfish (42.62)> diamond squid (15.09)>yellowfin tuna (10.29)>pelagic red crab (10.05)>panama lightfish (9.54)> jumbo squid (8.91). The selenium health benefit value (Se-HBV) was calculated to have an improved understanding of the health benefits and risk of fish consumption.

  14. Consequences experimentales des effets des fluctuations du vide sur la fluorescence parametrique et la generation du second harmonique en milieu confine

    NASA Astrophysics Data System (ADS)

    Robichaud, Luc

    Les fluctuations du vide, qui consistent en l'apparition momentanee de particules, ce qui est permit par le principe d'incertitude de Heisenberg, joue un role primordial dans les processus photoniques, en particulier les processus non-lineaires. Par la manipulation de ces fluctuations du vide a l'aide de confinement optique, on retrouve deux phenomenes particuliers : l'intensification de la fluorescence parametrique (Walker, 2008) et l'inhibition de la generation du second harmonique (Collette, 2013). Dans ce travail, on presente les resultats dans le cas classique ; c'est-a-dire sans fluctuations du vide et confinement. Par la suite, on presente les effets des fluctuations du vide et du confinement, ce qui mene aux deux effets mentionnes. Dans le cas de la fluorescence parametrique, le bruit quantique sur le champ interne et externe est calcule, le role du desaccord de phase dans le modele est expose et une generalisation tridimensionnelle est etudiee afin de generaliser la conception du modele d'un cas unidimensionnel a un cas tridimensionnel planaire. Dans le cas de la generation du second harmonique, les difficultes d'un modele purement tridimensionnel sont exposees et ensuite le cas limite planaire est etudie.

  15. Overview of 3D Documentation Data and Tools available for Archaeological Researches: case study of the Romanesque Church of Dugny-sur-Meuse (France)

    NASA Astrophysics Data System (ADS)

    Macher, H.; Grussenmeyer, P.; Kraemer, C.; Guillemin, S.

    2015-08-01

    In this paper, the 3D documentation of the full structure of the Romanesque church of Dugny-sur-Meuse is discussed. In 2012 and 2013, a 3D recording project was carried out under the supervision of the Photogrammetry and Geomatics Research Group from INSA Strasbourg (France) in cooperation with C. Kraemer, archaeologist from Nancy (France). The goal of the project was on one hand to propose new solutions and tools to the archaeologists in charge of the project especially for stone by stone measurements. On the other hand, a simplified 3D model was required by the local authorities for communication purposes. To achieve these goals several techniques were applied namely GNSS measurements and accurate traverse networks, photogrammetric recordings and terrestrial laser scanning acquisitions. The various acquired data are presented in this paper. Based on these data, several deliverables are also proposed. The generation of orthoimages from plane as well as cylindrical surfaces is considered. Moreover, the workflow for the creation of a 3D simplified model is also presented.

  16. A probable case of gigantism/acromegaly in skeletal remains from the Jewish necropolis of "Ronda Sur" (Lucena, Córdoba, Spain; VIII-XII centuries CE).

    PubMed

    Viciano, Joan; De Luca, Stefano; López-Lázaro, Sandra; Botella, Daniel; Diéguez-Ramírez, Juan Pablo

    2015-01-01

    Pituitary gigantism is a rare endocrine disorder caused by hypersecretion of growth hormone during growing period. Individuals with this disorder have an enormous growth in height and associated degenerative changes. The continued hypersecretion of growth hormone during adulthood leads to acromegaly, a condition related to the disproportionate bone growth of the skull, hands and feet. The skeletal remains studied belong to a young adult male from the Jewish necropolis of "Ronda Sur" in Lucena (Córdoba, Spain, VIII-XII centuries CE). The individual shows a very large and thick neurocranium, pronounced supraorbital ridges, an extremely prominent occipital protuberance, and an extremely large and massive mandible. Additional pathologies include enlargement of the vertebral bodies with degenerative changes, thickened ribs, and a slight increased length of the diaphysis with an increased cortical bone thickness of lower limbs. Comparative metric analysis of the mandible with other individuals from the same population and a contemporary Mediterranean population shows a trend toward acromegalic morphology. This case is an important contribution in paleopathological literature because it is a rare condition that has not been widely documented in ancient skeletal remains. PMID:25776010

  17. Fiabilité des structures mécaniques adaptatives: effet de la panne des actionneurs ou des capteurs sur la stabilité

    NASA Astrophysics Data System (ADS)

    Fall, H.; Charon, W.; Kouta, R.

    2002-12-01

    Ces dernières décennies, des activités significatives dans le monde étaient dirigées autour du contrôle actif. Le but de ces recherches était essentiellement d'améliorer les performances, la fiabilité et la sécurité des systèmes. Notamment dans le cas des structures soumises à des vibrations aléatoires. D'importants travaux ont été consacré à l'utilisation des “matériaux intelligents” comme capteurs et actionneurs. Cette article propose l'analyse de la fiabilité des systèmes mécaniques en étudiant les pannes des actionneurs ou des capteurs. L'effet de ces pannes sur la stabilité et la performance du système y est démontré. Les méthodologies de conception y sont rappelées. Des exemples numériques sont fournis à travers le contrôle d'un panneau sous chargement dynamique pour illustrer la méthode proposée.

  18. Application d'une technique de modelisation aerodynamique conceptuelle sur la simulation d'un pilote automatique a commande optimale pour un avion d'affaires

    NASA Astrophysics Data System (ADS)

    Pollender-Moreau, Olivier

    Ce document présente, dans le cadre d'un contexte conceptuel, une méthode d'enchaînement servant à faire le lien entre les différentes étapes qui permettent de réaliser la simulation d'un aéronef à partir de ses données géométriques et de ses propriétés massiques. En utilisant le cas de l'avion d'affaires Hawker 800XP de la compagnie Hawker Beechcraft, on démontre, via des données, un processus de traitement par lots et une plate-forme de simulation, comment (1) modéliser la géométrie d'un aéronef en plusieurs surfaces, (2) calculer les forces aérodynamiques selon une technique connue sous le nom de Vortex Lattice Method, (3) construire un modèle de vol servant à la simulation des aéronefs pour leur enveloppe de vol en ajoutant des fonctions supplémentaires, (4) construire un modèle de turbosoufflante simplifié, (5) développer un algorithme d'équilibre (trim) du mouvement longitudinal, (6) développer des algorithmes de contrôle à commande moderne, (7) développer certaines fonctions d'un système de pilotage automatique, et (8) rassembler le tout sous une même plate-forme de simulation. Afin de supporter ce travail, une application publique Matlab, connue sous le nom de Tornado, est utilisée conjointement avec d'autres fonctions pour la conception du modèle de vol aérodynamique. D'ailleurs, il sera démontré que le modèle de vol, quoiqu'il soit quand même crédible, ne concorde pas tout à fait avec les données de référence. Par contre, puisque le modèle des moteurs fonctionne bien, que l'algorithme d'équilibrage du mouvement longitudinal fonctionne bien et que les pôles des systèmes dynamiques concordent avec la littérature, les tests dynamiques effectués au sein de la plate-forme de simulation permettent d'obtenir des résultats fonctionnels et crédibles. D'ailleurs, deux systèmes d'augmentation de la stabilité basés sur la méthode de contrôle moderne LQR et couvrant l

  19. Biomagnification of mercury and its antagonistic interaction with selenium in yellowfin tuna Thunnus albacares in the trophic web of Baja California Sur, Mexico.

    PubMed

    Ordiano-Flores, Alfredo; Rosíles-Martínez, Rene; Galván-Magaña, Felipe

    2012-12-01

    Mercury and selenium concentrations were determined in muscle of 37 yellowfin tuna (Thunnus albacares) captured aboard of Mexican purse-seiners boats off western coast of Baja California Sur, between Punta Eugenia and Cabo Falso, from October to December 2006. Also, its prey (mainly, jumbo squid Dosidicus gigas and pelagic red crab Pleuroncodes planipes) were analyzed from the stomach contents. All the mercury values obtained were lower that mercury content recommended by standard legal limits for seafood adopted by Mexican norms (typically 0.5-1.0μg g(-1)). Mercury concentrations vary between 0.06 and 0.51μg g(-1) in yellowfin tuna, and from 0.01 to 0.20μg g(-1) in its prey, suggesting that mercury can accumulate in prey tissues and that of their predator. Biomagnification factors (BMF) between predator-prey associations were calculated. The BMFs were >1, indicating that mercury biomagnifies along the food web of yellowfin tuna. In all species studied there was a molar excess of selenium over mercury. The rank order of mean selenium/mercury molar ratios was for pufferfish (42.62)> diamond squid (15.09)>yellowfin tuna (10.29)>pelagic red crab (10.05)>panama lightfish (9.54)> jumbo squid (8.91). The selenium health benefit value (Se-HBV) was calculated to have an improved understanding of the health benefits and risk of fish consumption. PMID:23059106

  20. Fine scale daily movements and habitat use of East Pacific green turtles at a shallow coastal lagoon in Baja California Sur, Mexico

    USGS Publications Warehouse

    Senko, Jesse; Koch, Volker; Megill, William M.; Carthy, Raymond R.; Templeton, R.obert P.; Nichols, Wallace J.

    2010-01-01

    Green turtles spend most of their lives in coastal foraging areas where they face multiple anthropogenic impacts. Therefore, understanding their spatial use in this environment is a priority for conservation efforts. We studied the fine scale daily movements and habitat use of East Pacific green turtles (Chelonia mydas) at Laguna San Ignacio, a shallow coastal lagoon in Baja California Sur, Mexico where sea turtles are subject to high levels of gillnet bycatch and directed hunting. Six turtles ranging from 44.6 to 83.5 cm in straight carapace length were tracked for short deployments (1 to 6 d) with GPS-VHF telemetry. Turtles were active throughout diurnal, nocturnal, and crepuscular periods. Although they moved greater total distances during daytime, their speed of travel and net displacement remained consistent throughout 24-h periods. A positive selection for areas of seagrass and moderate water depth (5 to 10 m) was determined using Ivlev's electivity index, with neutral selection for shallow water (< 5 m) and avoidance of deep water (> 10 m). Turtles exhibited two distinct behavioral movement patterns: circular movements with high fidelity to the capture–release location and meandering movements with low fidelity to the capture–release location. Our results indicate that green turtles were active throughout the diel cycle while traveling large distances and traversing multiple habitats over short temporal scales.

  1. Palaeo-ecological quality status based on foraminifera of Boulogne-sur-Mer harbour (Pas-de-Calais, Northeastern France) over the last 200 years.

    PubMed

    Francescangeli, F; Armynot du Chatelet, E; Billon, G; Trentesaux, A; Bouchet, V M P

    2016-06-01

    Over the last centuries, coastal areas have experienced dramatic degradations of their environmental quality, which has led to a huge reduction of marine biodiversity. The objective of the present study was to use geochemical parameters and benthic fossil foraminifera to assess environmental changes that have occurred over the last 200 years in a harbour area (Boulogne-sur-Mer, Northern France) heavily modified by human activities. A multidisciplinary approach including major and trace metals, grain-size, total organic carbon and benthic fossil foraminifera, has been performed on a 33-cm long core. The dating was carried out using the activity of (210)Pb and (137)Cs. Embayment of the area and increase of trace metals concentrations induced a shift in benthic communities. Human activities modified a sandy nearshore bank, colonized by typical marine foraminiferal species, such as Cribroelphiudium excavatum, into a sheltered environment, dominated by brackish end-members, such as Haynesina germanica. Along the sedimentary record, the interaction between meiofaunal and geochemical elements made it possible to distinguish between a pre-impacted period and an industrial period. The upper part of the core reflects better ecological conditions, indicating an environmental recovery. Our results provide baselines for future environmental bio-monitoring in the area. PMID:27074196

  2. Rapport sur l'état du patrimoine astronomique dans les observatoires français de la fin du XIXè siècle

    NASA Astrophysics Data System (ADS)

    Damm, E.; Pécontal, E.

    2012-12-01

    Suite au colloque sur la sauvegarde du patrimoine astronomique organisé par le MAEE et la SAF, sous l'égide de l'UNESCO, qui a conduit à l'adoption de la Déclaration de Paris, les directeurs d'observatoires institutionnels qui étaient absents du colloque ont ressenti le besoin de discuter de ces conclusions prises en leur nom. L'initiative d'organiser une réunion des directeurs des Observatoires des Sciences de l'Univers (OSU) à ce sujet le 30 janvier 2012 a été prise par François Vernotte, directeur de l'Observatoire de Besançon. Le présent compte-rendu de visite résulte d'une initiative spontanée d'Emmanuel Pécontal, astronome responsable du Patrimoine à l'observatoire de Lyon, et d'Evelyne Damm, membre de la Commission Nationale de classement des Monuments Historiques (CNMH) et élue à la communauté d'agglomération des Portes de l'Essonne oû est sis l'observatoire de Camille Flammarion.

  3. A probable case of gigantism/acromegaly in skeletal remains from the Jewish necropolis of "Ronda Sur" (Lucena, Córdoba, Spain; VIII-XII centuries CE).

    PubMed

    Viciano, Joan; De Luca, Stefano; López-Lázaro, Sandra; Botella, Daniel; Diéguez-Ramírez, Juan Pablo

    2015-01-01

    Pituitary gigantism is a rare endocrine disorder caused by hypersecretion of growth hormone during growing period. Individuals with this disorder have an enormous growth in height and associated degenerative changes. The continued hypersecretion of growth hormone during adulthood leads to acromegaly, a condition related to the disproportionate bone growth of the skull, hands and feet. The skeletal remains studied belong to a young adult male from the Jewish necropolis of "Ronda Sur" in Lucena (Córdoba, Spain, VIII-XII centuries CE). The individual shows a very large and thick neurocranium, pronounced supraorbital ridges, an extremely prominent occipital protuberance, and an extremely large and massive mandible. Additional pathologies include enlargement of the vertebral bodies with degenerative changes, thickened ribs, and a slight increased length of the diaphysis with an increased cortical bone thickness of lower limbs. Comparative metric analysis of the mandible with other individuals from the same population and a contemporary Mediterranean population shows a trend toward acromegalic morphology. This case is an important contribution in paleopathological literature because it is a rare condition that has not been widely documented in ancient skeletal remains.

  4. Galileo NIMS Observations of Europa

    NASA Astrophysics Data System (ADS)

    Shirley, J. H.; Ocampo, A. C.; Carlson, R. W.

    2000-10-01

    The Galileo spacecraft began its tour of the Jovian system in December, 1995. The Galileo Millenium Mission (GMM) is scheduled to end in January, 2003. The opportunities to observe Europa in the remaining orbits are severely limited. Thus the catalog of NIMS observations of Europa is virtually complete. We summarize and describe this extraordinary dataset, which consists of 77 observations. The observations may be grouped in three categories, based on the scale of the data (km/pixel). The highest-resolution observations, with projected scales of 1-9 km/pixel, comprise one important subset of the catalog. These 29 observations sample both leading and trailing hemispheres at low and high latitudes. They have been employed in studies exploring the chemical composition of the non-ice surface materials on Europa (McCord et al., 1999, JGR 104, 11,827; Carlson et al., 1999, Science 286, 97). A second category consists of regional observations at moderate resolution. These 15 observations image Europa's surface at scales of 15-50 km/pixel, appropriate for construction of regional and global mosaics. A gap in coverage for longitudes 270-359 W may be partially filled during the 34th orbit of GMM. The final category consists of 33 global observations with scales ranging upward from 150 km/pixel. The noise levels are typically much reduced in comparison to observations taken deep within Jupiter's magnetosphere. Distant observations obtained during the 11th orbit revealed the presence of hydrogen peroxide on Europa's surface (Carlson et al., 1999b, Science 283, 2062). NIMS observations are archived in ISIS-format "cubes," which are available to researchers through the Planetary Data System (http://www-pdsimage.jpl.nasa.gov/PDS/Public/Atlas/Atlas.html). Detailed guides to every NIMS observation may be downloaded from the NIMS web site (http://jumpy.igpp.ucla.edu/ nims/).

  5. Mise à jour sur la prévention et le dépistage selon l’âge à l’intention des médecins de soins primaires canadiens

    PubMed Central

    Shimizu, Tawnya; Bouchard, Manon; Mavriplis, Cleo

    2016-01-01

    Résumé Objectif Faire la synthèse des meilleures lignes directrices fondées sur des données probantes concernant la prévention et le dépistage chez les adultes canadiens selon l’âge. Qualité des données Les recommandations du Groupe d’étude canadien sur les soins de santé préventifs représentent la source principale des renseignements et sont complétées par les recommandations pertinentes du Preventive Services Task Force des États-Unis lorsque celles du Groupe d’étude canadien étaient inaccessibles ou désuètes. Les guides de pratique des principales organisations nationales axées spécifiquement sur une maladie ou une spécialité ont aussi fait l’objet d’une révision pour prendre en compte les données factuelles les plus récentes. Message principal Les interventions de dépistage recommandées selon l’âge et le sexe sont présentées dans un tableau de synthèse où est mise en évidence la qualité des données à l’appui de ces recommandations. Un exemple de modèle à suivre dans les dossiers médicaux électroniques ou sur papier est aussi proposé. Conclusion Qu’il s’agisse d’une visite consacrée à la prévention ou d’une occasion saisie autrement de faire du counseling et du dépistage de prévention chez leurs patients, les médecins de soins primaires peuvent se servir de cette synthèse des recommandations fondées sur des données probantes pour maximiser leur efficience et prévenir d’importantes omissions ou des dépistages inutiles.

  6. Observing ENSO then and now

    NASA Astrophysics Data System (ADS)

    McPhaden, M. J.

    2013-12-01

    The 1982-83 El Nino was the largest on record when it occurred. However, it was neither predicted nor even detected until nearly at it's peak. The inability to effectively observe or forecast evolving climatic conditions in the tropical Pacific motivated a community wide effort to develop an extensive ocean observing system capable of reporting data in real-time across the basin. That observing system was implemented over the ten year period (1985-94) of the Tropical Ocean Global Atmosphere (TOGA) program and has continued to evolve with the introduction new observing system components, improved measurement technologies, and wider data access through the internet. Data from this observing system have fundamentally advanced ENSO research, enabled skillful seasonal prediction, and provided a rich source of information for studies of climate variability and change. This presentation will review some of the successes of the past 30 years as well as highlight challenges in sustaining future ocean observations for climate.

  7. NS&T Management Observations

    SciTech Connect

    Gianotto, David

    2014-09-01

    The INL Management Observation Program (MOP) is designed to improve managers and supervisors understanding of work being performed by employees and the barriers impacting their success. The MOP also increases workers understanding of managements’ expectations as they relate to safety, security, quality, and work performance. Management observations (observations) are designed to improve the relationship and trust between employees and managers through increased engagement and interactions between managers and researchers in the field. As part of continuous improvement, NS&T management took initiative to focus on the participation and quality of observations in FY 14. This quarterly report is intended to (a) summarize the participation and quality of management’s observations, (b) assess observations for commonalities or trends related to facility or process barriers impacting research, and (c) provide feedback and make recommendations for improvements NS&T’s MOP.

  8. Observability of Neuronal Network Motifs

    PubMed Central

    Whalen, Andrew J.; Brennan, Sean N.; Sauer, Timothy D.; Schiff, Steven J.

    2014-01-01

    We quantify observability in small (3 node) neuronal networks as a function of 1) the connection topology and symmetry, 2) the measured nodes, and 3) the nodal dynamics (linear and nonlinear). We find that typical observability metrics for 3 neuron motifs range over several orders of magnitude, depending upon topology, and for motifs containing symmetry the network observability decreases when observing from particularly confounded nodes. Nonlinearities in the nodal equations generally decrease the average network observability and full network information becomes available only in limited regions of the system phase space. Our findings demonstrate that such networks are partially observable, and suggest their potential efficacy in reconstructing network dynamics from limited measurement data. How well such strategies can be used to reconstruct and control network dynamics in experimental settings is a subject for future experimental work. PMID:25909092

  9. Observing with the Armillary Astrolabe

    NASA Astrophysics Data System (ADS)

    Wlodarczyk, J.

    1987-08-01

    The author investigates the merits and limitations of the armillary astrolabe, which served for direct observations of the ecliptic longitudes and latitudes of the heavenly bodies from Antiquity to the end of the sixteenth century. Observations made with a modern replica of the instrument are compared with historical astrolabic observations as reported by Ptolemy in the Almagest and with measurements made in 1503-4 by Bernard Walther in Nuremberg.

  10. Observations of Novae From ROAD

    NASA Astrophysics Data System (ADS)

    Hambsch, F.-J.

    2014-12-01

    The author discusses observations of galactic novae and some extragalactic supernovae from his remote observatory ROAD (Remote Observatory Atacama Desert) he commenced in August 2011 with Nova Lupi 2011 (PR Lup). The observed novae are mainly chosen according to AAVSO Alert Notices and AAVSO Special Notices as published on their website. Examples of dense observations of different novae are presented. The focus goes to the different behaviors of their light curves. It also demonstrates the capability of the remote observatory ROAD.

  11. Observations of Novae from ROAD

    NASA Astrophysics Data System (ADS)

    Hambsch, Franz-Josef

    2014-05-01

    The author discusses observations of galactic novae and some extragalactic supernovae from his remote observatory ROAD (Remote Observatory Atacama Desert) he commenced in August 2011 with Nova Lupi 2011 (PR Lup). The observed novae are mainly chosen according to alert notices and special notices of the AAVSO as published on their website. Examples of dense observations of different novae are presented. The focus goes to the different behaviors of their light curves. It also demonstrates the capability of the remote observatory ROAD.

  12. Magnetopause structure from satellite observations

    NASA Technical Reports Server (NTRS)

    Sonnerup, B. U. O.

    1979-01-01

    Observations on magnetopause structure are reported. Major topics covered include: classical reconnection, transport mechanisms, magnetospheric boundary layers, tearing modes, and Jupiter's magnetopause.

  13. Observations of Solar Radio Transients

    NASA Astrophysics Data System (ADS)

    Paige, Giorla

    2011-05-01

    A low frequency radio telescope has been recently been constructed on the campus of the The College of New Jersey (TCNJ) and has begun conducting observations at 20MHz as part of NASA'a Radio Jove program. This instrument is capable of observations of solar radio emission including strong prompt radio emission associated with solar burst events. We will discuss solar observations conducted with this instrument as well as an effort to conduct coincident observations with the Eight-meter-wavelength Transient Array (ETA) and the Long Wavelength Array (LWA).

  14. Mauna Kea Observatory infrared observations

    NASA Technical Reports Server (NTRS)

    Jefferies, J. T.

    1974-01-01

    Galactic and solar system infrared observations are reported using a broad variety of radiometric and spectroscopic instrumentation. Infrared programs and papers published during this period are listed.

  15. Observations of active chromosphere stars

    NASA Technical Reports Server (NTRS)

    Africano, J. L.; Klimke, A.; Stencel, R. E.; Noah, P. V.; Bopp, B. W.

    1983-01-01

    It is pointed out that spectroscopic signatures of stellar chromospheric activity are readily observable. The present study is concerned with new photometric and spectroscopic observations of active-chromosphere RS CVn, BY Dra, and FK Com stars. Attention is given to the first results of a synoptic monitoring program of many active chromosphere stars. During the time from 1980 to 1982, photometric and spectroscopic observations of 10 known or suspected active-chromosphere objects were made. The results regarding the individual stars are discussed. Seven stars observed with the International Ultraviolet Explorer (IUE) are all spectroscopic binaries.

  16. Quantum estimation by local observables

    SciTech Connect

    Hotta, Masahiro; Ozawa, Masanao

    2004-08-01

    Quantum estimation theory provides optimal observations for various estimation problems for unknown parameters in the state of the system under investigation. However, the theory has been developed under the assumption that every observable is available for experimenters. Here, we generalize the theory to problems in which the experimenter can use only locally accessible observables. For such problems, we establish a Cramer-Rao-type inequality by obtaining an explicit form of the Fisher information as a reciprocal lower bound for the mean-square errors of estimations by locally accessible observables. Furthermore, we explore various local quantum estimation problems for composite systems, where nontrivial combinatorics is needed for obtaining the Fisher information.

  17. Tuberculome myocardique: localisation inhabituelle de la tuberculoseà propos d'une nouvelle observation avec une revue de la littérature

    PubMed Central

    Lambatten, Dalal; Hammi, Sanaa; Rhofir, Yasmina; Bourkadi, Jamal Eddine

    2016-01-01

    Nous rapportons l'observation d'un patient de 50 ans présentant une masse tumorale du ventricule gauche évoluant dans un contexte d'altération de l’état général et de fièvre. Cette masse a été objectivée par l’échocardiographie réalisée pour l'exploration d'une cardiomégalie radiologique. L'aspect en imagerie par résonance magnétique était évocateur d'un tuberculome intra myocardique. A travers notre observation, nous proposons une revue de la littérature sur cette localisation inhabituelle de la tuberculose. PMID:27583096

  18. Science Shorts: Observation versus Inference

    ERIC Educational Resources Information Center

    Leager, Craig R.

    2008-01-01

    When you observe something, how do you know for sure what you are seeing, feeling, smelling, or hearing? Asking students to think critically about their encounters with the natural world will help to strengthen their understanding and application of the science-process skills of observation and inference. In the following lesson, students make…

  19. Ionospheric observations in southern Norway

    NASA Astrophysics Data System (ADS)

    Kjørsvik, N.; Øvstedal, O.; Pettersen, B. R.; Svendsen, J. G. G.

    2003-04-01

    A permanent GPS reference receiver is established in station AK06 at the campus of NLH, Norway. The monumentation, hardware, software and network connection is according to IGS practice. In this poster the first application of dual frequency GPS observations from this station is presented. Carrier phase and pseudorange observations at 1 Hz are used to monitor ionospheric TEC values. The processing is carried out in near real time. Observation files containing one hour of observations are added to moving observation files containing 24 hours of data. Differential Code Biases (DCB) in the satellites are taken from the IONEX (IONosphere Exchange format) computed by the ionosphere working group of the International GPS Services. The IGS estimate daily Global Ionospheric Models with DCBs and ionospheric Total Electron Content (TEC) parameters. Daily estimates for the receiver DCB are estimated using dual frequency pseudorange observations and satellite DCBs and TEC values from IGS. Final TEC values are estimated using undifferenced carrier phase observations leveled to pseudorange. Hourly snap shots as well as animations are presented on a web-page. GPS-observations from other stations will be added in order to extend the area of coverage.

  20. Learning to Observe "and" Infer

    ERIC Educational Resources Information Center

    Hanuscin, Deborah L.; Park Rogers, Meredith A.

    2008-01-01

    Researchers describe the need for students to have multiple opportunities and social interaction to learn about the differences between observation and inference and their role in developing scientific explanations (Harlen 2001; Simpson 2000). Helping children develop their skills of observation and inference in science while emphasizing the…

  1. The Differentiated Classroom Observation Scale

    ERIC Educational Resources Information Center

    Cassady, Jerrell C.; Neumeister, Kristie L. Speirs; Adams, Cheryll M.; Cross, Tracy L.; Dixon, Felicia A.; Pierce, Rebecca L.

    2004-01-01

    This article presents a new classroom observation scale that was developed to examine the differential learning activities and experiences of gifted children educated in regular classroom settings. The Differentiated Classroom Observation Scale (DCOS) is presented in total, with clarification of the coding practices and strategies. Although the…

  2. Observing Teaching. SEDA Paper 79.

    ERIC Educational Resources Information Center

    Brown, Sally, Ed.; And Others

    This publication offers practical support to those in British higher education implementing the Observation of Teaching governmental directives. It provides discussion of key issues as well as a range of materials on how to carry out teaching observation including 23 checklists. The materials are grouped in four main areas: general issues, self…

  3. Seeing the Invisible: Classroom Observation.

    ERIC Educational Resources Information Center

    Beirne, Mary Helen

    1997-01-01

    Presents results from a study investigating the effects of professional training on teachers' use of observations to assess elementary students. Describes the training program and its focus on professional empowerment, strategy development for observation-based assessment, and learning the value of peer support. Reports that participants'…

  4. Infrared observations of the planets

    NASA Technical Reports Server (NTRS)

    Low, F. J.

    1974-01-01

    The planetary observations presented are divided into three parts: (1) infrared photometry at all wavelengths accessible from the ground; (2) high resolution infrared mapping of Jupiter with special emphasis at 5 microns; and (3) extensive infrared observations of Comet Kohoutek. Results are briefly summarized.

  5. Learning to Learn through Observation.

    ERIC Educational Resources Information Center

    Browder, Diane M.; And Others

    1987-01-01

    Observational learning is theoretically conceptualized as a skill that can be developed along a learning hierarchy from acquisition and fluency development to generalization of imitative behavior. This review characterizes these levels of observational learning and details differential teaching strategies that have been attempted at each level…

  6. chi Cygnids observation in Japan

    NASA Astrophysics Data System (ADS)

    Shiba, Yasuo

    2015-12-01

    The chi Cygnids (IAU MDC code: 00757 CCY) are a new meteor shower reported by Green (2015) green15 in 2015 September. I find members of the chi Cygnids in the 2015 data of the Japanese TV meteor observing network the `SonotaCo network'. Additionally a few meteors from this shower were observed in 2010.

  7. New particle observations in SELEX

    SciTech Connect

    Jun, Soon Yung; /Carnegie Mellon U.

    2004-12-01

    Particle observations in data from SELEX, the charm hadro-production experiment (E781) at Fermilab are reviewed. These include observations of the doubly charmed baryon {Xi}{sub cc}{sup +}(3520) and the charmed strange meson D{sub sJ}{sup +}(2632).

  8. Observation of Persons and Contexts.

    ERIC Educational Resources Information Center

    Gump, Paul V.

    Observational approaches used by ecological psychologists can focus on the behavior of persons or on their settings. The options for subject-centered observation are diary methods, specimen records, time sampling, and event sampling or critical incident recording. Serious limitations correlated to the time interval method, as it is often applied,…

  9. A novel extended state observer.

    PubMed

    Xiong, Shaofeng; Wang, Weihong; Liu, Xiaodong; Chen, Zengqiang; Wang, Sen

    2015-09-01

    A novel extended state observer, which feeds back the output estimation error via both nonlinear and switching terms, is put forward for the first time in this paper. No longer neglecting the lumped uncertainty׳s first time derivative, the problem of disturbance observer design is transformed into the problem of state observer design in the presence of external disturbance. The switching term of the output estimation error is employed to counteract the adverse effect of external disturbance. The newly developed extended state observer provides an attractive solution to the issue of high precision motion control system. Both numerical simulation and experimentation on a speed turntable with temperature box are implemented to verify the performance of the proposed newly developed extended state observer. PMID:26275404

  10. Mars Observer Orbit Insertion Briefing

    NASA Technical Reports Server (NTRS)

    1993-01-01

    Steve Wall is the host of this video entitled, "Return to the Red Planet". Live animation of the Mars Observer orbiting Mars is presented. Steve Wall explains the spacecraft insertion maneuver and also explains the purpose for the Mars Observer launch. Live coverage of the Cape Canaveral launch of the Mars Observer is also presented. Suzanne Dodd, Chief of the Mission Planning team describes the burn start and how the spacecraft will be captured by Mars' gravity. Glenn Cunningham, Mars Observer Project Manager, gives background information on the Mars Observer and describes the organizations behind the Mars Observer Spacecraft, such as the Deep Space Network, the Mission Operation Support Office, Science Investigators, the Flight Engineering Office, Operations Office, and the Ground Data System Office. Dr. William Piotrowski, Acting Director, Solar System Exploration Division, NASA, talks about the purpose of the Mars Pathfinder which is to develop the technology and systems for landing small science packages on Mars. Mr. Roger Gibbs, Former Mars Observer Spacecraft Systems Engineer, tells us how the Mars Observer was built and describes the structural elements on the Mars Observer. The 11-month cruise period for the spacecraft is given by Joseph Beerer, Manager of the Engineering office. The thrust for the Mars Orbit Insertion is described by Ronald Klemetson, Technical Manager, Propulsion Subsystem Jet Propulsion Laboratory (JPL). George Chen, Lead Engineer Attitude and Articulation Subsystem Spacecraft Team, explains the importance of the attitude control engines on the Spacecraft. Marvin Traxler, Manager of Tracking and Data Acquisition, describes how searching for a signal from the Mars Observer works. See NONP-NASA-VT-2000081555 for a continuation of this discussion with Marvin Traxler.

  11. Versión final del relevamiento de HI en el hemisferio sur realizado desde el IAR

    NASA Astrophysics Data System (ADS)

    Bajaja, E.; Arnal, E. M.; Morras, R.; Pöppel, W. G. L.; Kalberla, P.

    The incorporation to the IAR equipment, of the Arecibo 1008 channels digital auto-correlator and of a cooled receiver for 21 and 18 cm and two polarizations, built at the MPIfR at Bonn (Germany) with the participation of argentine Engineers, made it possible to carry out the surveying of the HI in the part of the southern sky visible with the IAR dish No. 1. The parameters chosen for this survey were similar to those of a similar survey of HI in the northern sky, made from Dwingeloo (Holland) by the Leiden Observatory, in order that both surveys were compatible for producing a whole sky HI survey. The main parameters were: a) Spatial coverage: 50980 points below -25o in declination, spaced 0oċ5 in galactic latitude and approximately 0oċ5/cos φ in longitude, with an angular resolution of 0oċ5; b) Velocity coverage: from -527 to +528 km s-1 with channels spaced 1.047 km s-1 and with a velocity resolution of 1.27 km s-1, and c) Sensitivity: rms noise ≤ 70 mK. The observations started in 1994 and ended in 1997. Spectra reduction was completed in 1999 without including stray radiation corrections. The work for this correction started in 2002 and was completed recently through a collaboration between the IAR and the Radioastronomisches Institut der Universität Bonn. The maps produced with the whole sky HI survey, built adding the northern and southern surveys, show the consistency of the observations and corrections in both surveys and the enormous amount of information provided by them.

  12. Observability and observer design for hybrid multicell choppers

    NASA Astrophysics Data System (ADS)

    Bejarano, F. J.; Ghanes, M.; Barbot, J.-P.

    2010-03-01

    Multicell choppers are part of a class of hybrid systems in which the continuous state vector is always unobservable, in the sense that the observability matrix never has full rank. Due to their hybrid behaviour, the recent concept of Z(T N )-observability can be applied and analysed in the context of multicell choppers, which allows to give conditions, in terms of the switching sequence, under which the voltage across each capacitor can be reconstructed, not instantly, but after some number of switchings. The case when a DC-motor is coupled to the multicell chopper is also considered. It is shown that, under certain admissible assumptions, the voltages across the capacitors and the motor speed can be acceptably estimated. Two observers, one based on the super-twisting algorithm and the other one based on an adaptive approach, are designed. Additionally, we design an observer for the partial state observation. Simulations are given where the proposed observers are compared and the effectiveness of both is shown.

  13. Ideal AFROC and FROC observers.

    PubMed

    Khurd, Parmeshwar; Liu, Bin; Gindi, Gene

    2010-02-01

    Detection of multiple lesions in images is a medically important task and free-response receiver operating characteristic (FROC) analyses and its variants, such as alternative FROC (AFROC) analyses, are commonly used to quantify performance in such tasks. However, ideal observers that optimize FROC or AFROC performance metrics have not yet been formulated in the general case. If available, such ideal observers may turn out to be valuable for imaging system optimization and in the design of computer aided diagnosis techniques for lesion detection in medical images. In this paper, we derive ideal AFROC and FROC observers. They are ideal in that they maximize, amongst all decision strategies, the area, or any partial area, under the associated AFROC or FROC curve. Calculation of observer performance for these ideal observers is computationally quite complex. We can reduce this complexity by considering forms of these observers that use false positive reports derived from signal-absent images only. We also consider a Bayes risk analysis for the multiple-signal detection task with an appropriate definition of costs. A general decision strategy that minimizes Bayes risk is derived. With particular cost constraints, this general decision strategy reduces to the decision strategy associated with the ideal AFROC or FROC observer.

  14. Solar Ca II K Observations

    NASA Astrophysics Data System (ADS)

    Bertello, Luca; Pevtsov, Alexei A.; Tlatov, Andrey; Singh, Jagdev

    2016-07-01

    Some of the most important archives of past and current long-term solar synoptic observations in the resonance line of Ca II K are described here. These observations are very important for understanding the state of the solar magnetism on time scales up to several decades. The first observations of this kind began in 1904 at the Kodaikanal Observatory (India), followed by similar programs at different other locations. Regular full-disk Ca II K monitoring programs started in 1915 at the Mount Wilson Observatory (USA) and in 1917 at the National Solar Observatory of Japan. Beginning in 1919 and in 1926 regular observations were taken also at the Paris-Meudon Observatory (France) and at the "Donati solar tower telescope of the Arcetri Astrophysical Observatory in Italy, respectively. In 1926 the the Astronomical Observatory of the Coimbra University in Portugal started its own program of Ca II K observations. Although some of these programs have been terminated over the years, their data archives constitute a unique resource for studies of solar variability. In the early 1970s, the National Solar Observatory (NSO) at Sacramento Peak (USA) started a new program of daily Sun-as-a-star observations in the Ca II K line. Today the NSO is continuing these observations through its Synoptic Optical Long-term Investigations of the Sun (SOLIS) facility.

  15. Impact des produits de lessivage de feuilles mortes sur la teneur en oxygène de l'eau et sur la survie d'un gastéropode

    NASA Astrophysics Data System (ADS)

    Chergui, H.; Haddy, L.; Markaoui, M.; Pattee, E.

    The impact of the leaching of oleander, Nerium oleander, and willow, Salix pedicellata, leaves on the aquatic environment was investigated in the laboratory. The leaves were collected on the banks of a Moroccan stream, leachate polyphenols were analysed, and leachate toxic effects on the dominant gastropod species of the stream were investigated. The following factors were considered: leaf species, dry or fresh state of the leaves, litter concentration, duration of leaching, temperature. Within the first 8-12 hrs of submersion, the litter of both species caused a great depletion of dissolved oxygen. Later, oxygen consumption decreased. Dry oleander leaves caused a greater drop in oxygen concentration than fresh oleander leaves. The opposite was observed in willow leaves, most clearly at 5 and 10°C. At higher temperatures (20 and 25°C), oxygen nearly totally disappeared under all conditions, leaving 0 to 2 mg.I -1 after 48 hours. Whether fresh or dry, oleander leaves always caused a greater oxygen depletion than willow leaves. Willow leaves contained more tannin-and non-tannin-polyphenols than oleander leaves, and their leaching released more of these compounds, especially in dry leaves. The leaching of both leaf species only had a toxic effect on the gastropods at the higher temperatures (20 and 25°C), thus suggesting that the toxic effect was mainly due to lack of oxygen in the water. At these temperatures, the toxic effect of dry leaves was greater than that of fresh leaves. Oleander proved more toxic than willow, presumably under the influence of both lack of oxygen and toxic heterosides.

  16. L'impact de la texture sur la reaction en phase solide du nickel avec le silicium

    NASA Astrophysics Data System (ADS)

    Gaudet, Simon

    Microelectronics is a 300 G$ industry based on constant improvement of transistors. NiSi is currently the material of choice for the formation of contacts on the sources and drains of transistors with critical dimensions below 50 nm. Contacts are formed through a solid state reaction between Ni and Si. During the reaction an interdiffusion between Ni and Si occurs and result in formation of multiple phases. The temperature and the sequence at which those phases are observed during annealing are highly dependent on doping concentration and nature, thickness deposited, geometry, or alloying elements. On a single chip, billions of transistors with different sets of characteristics coexist and their contacts are all form simultaneously. At each transistor generation, the integration of NiSi is therefore a new challenge. This thesis allows to better understanding of the reaction and the process variations, notably by the observation of a metastable phase playing a key role in the reaction. We developed an experimental approach using x-ray diffraction to effectively characterize the entire reciprocal space. This experimental technique allows us to identify, using a single measurement, the texture, and nature of all phases in a sample, deformations of the lattice, signals from the thermal diffuse scattering resulting from the interaction of the x-rays with the phonons of the substrate and the presence of planar defects. This technique allowed us to demonstrate that the texture of the phases forming has a crucial impact on the reaction between Ni and Si or is the marker of phenomenon important to understand the reaction. Software, developed to process the raw data and analyze the three dimensional reciprocal space, were made available to the scientific community. First, we characterize the reaction of 10 nm Ni on Si(001). During the reaction, the first phases to form are Ni2Si and an epitaxial phase at the interface. The Ni2Si phase is consumed by the metastable theta

  17. IUE observations of young variables

    NASA Technical Reports Server (NTRS)

    Gahm, G. F.

    1981-01-01

    A number of far UV spectrograms of young variable stars have become available through observations with the IUE satellite. Several T Tauri stars and Herbig type Be- and Ae-stars in dark nebulae were observed and spectrograms of a total of 17 stars, which were considered to be very young pre-main-sequence stars, were collected. In many of these cases only part of the spectral region available at the IUE is covered and there are examples where large spectral regions are severely underexposed. With a few exceptions, the stars have been observed with the low resolution cameras, providing spectra resolutions of 6 to 7 A.

  18. Mars Observer magnetic fields investigation

    NASA Technical Reports Server (NTRS)

    Acuna, M. H.; Connerney, J. E. P.; Wasilewski, P.; Lin, R. P.; Anderson, K. A.; Carlson, C. W.; Mcfadden, J.; Curtis, D. W.; Reme, H.; Cros, A.

    1992-01-01

    The magnetic fields experiment designed for the Mars Observer mission will provide definitive measurements of the Martian magnetic field from the transition and mapping orbits planned for the Mars Observer. The paper describes the instruments (which include a classical magnetometer and an electron reflection magnetometer) and techniques designed to investigate the nature of the Martian magnetic field and the Mars-solar wind interaction, the mapping of crustal magnetic fields, and studies of the Martian ionosphere, which are activities included in the Mars Observer mission objectives. Attention is also given to the flight software incorporated in the on-board data processor, and the procedures of data processing and analysis.

  19. HEGRA Observations of Galactic Sources

    NASA Astrophysics Data System (ADS)

    Völk, H.; Hegea Collaboration

    2000-06-01

    In this talk I will first give a summary of the observations of expected Galactic TeV gamma-ray sources with the HEGRA CT-Sytem since the Kruger Park Workshop in 1997. Then I will go into some detail regarding the observations of Supernova Remnants (SNRs), especially those of Tycho's SNR and of Cas A. The emphasis will not be on all aspects of these published data. I will rather review the selection of these observational targets, and discuss some of the physical implications of the results.

  20. HEGRA observations of Galactic sources

    NASA Astrophysics Data System (ADS)

    HEGRA Collaboration

    2000-06-01

    In this talk I will first give a summary of the observations of expected Galactic TeV γ-ray sources with the HEGRA CT-System since the Kruger Park Workshop in 1997. Then I will go into some detail regarding the observations of Supernova Remnants (SNRs), especially those of Tycho's SNR and of Cas A. The emphasis will not be on all aspects of these published data. I will rather review the selection of these observational targets, and discuss some of the physical implications of the results. .

  1. The ESO Observing Programmes Committee

    NASA Astrophysics Data System (ADS)

    Westerlund, B. E.

    1982-06-01

    Since 1978 the ESO Observing Programmes Committee (OPC) has "the function to inspect and rank the proposals made for observing programmes at La Silla, and thereby to advise the Director General on the distribution of observing time". The members (one from each member country) and their alternates are nominated by the respective national committees for five-year terms (not immediately renewable). The terms are staggered so that each year one or two persons are replaced. The Chairman is appointed annually by the Council. He is invited to attend Council meetings and to report to its members.

  2. AUV Mapping and ROV Exploration of Los Frailes Submarine Canyon, Cabo Pulmo National Marine Park, Baja California Sur, Mexico

    NASA Astrophysics Data System (ADS)

    Troni, G.; Caress, D. W.; Graves, D.; Thomas, H. J.; Thompson, D.; Barry, J. P.; Aburto-Oropeza, O.; Johnson, A. F.; Lundsten, L.

    2015-12-01

    the thalweg, largely bare of sediment. ROV video indicates the north wall is composed of granitic rock similar to outcrops on shore. Few fish or other animals are observed below 100 m depth, but considerable diversity exists along the canyon walls above 100 m depth. These observations are consistent with a pronounced oxygen minimum zone present below about 100 m depth.

  3. Assessment by regional modelling of the impact of monopile foundations on the hydrodynamics and sediment transport: case of Courseulles-sur-Mer (France) wind farm

    NASA Astrophysics Data System (ADS)

    Rivier, Aurélie; Bennis, Anne-Claire; Pinon, Grégory; Magar, Vanesa; Gross, Markus

    2015-04-01

    Offshore monopile foundations of wind turbines modify hydrodynamics and sediment transport at local scale and also at regional scale. The aim of this work is to assess these changes and to parametrize them in a regional model. These modifications were previously evaluated using the regional circulation model MARS3D (Lazure and Dumas, 2008) in tests-cases (Rivier et al., 2014) using two approaches: in the first approach, monopiles are explicitly modelled in the mesh as dry cells and in the second approach a sub-grid parametrization which considers the drag force exerted by a monopile on the flow is used. The sub-grid parametrization is improved close to the bed in this paper by adding a drag force term in the momentum equations, source terms in the turbulence model and by increasing the bed shear stress at monopile location. Changes in hydrodynamics regime, especially near-bed, affect sediment transport regime and modifications due to monopiles on sediment dynamics is also investigated using the MARS3D sediment transport module (Le Hir et al., 2011) which solves the advection-diffusion equations. Test-cases are run using hydrodynamical conditions and sediment grain sizes typical from the area located off Courseulles-sur-Mer (Normandy, France) where an offshore wind farm is planned to be built. Velocity, turbulent kinetic energy and bed thickness changes due to the monopile simulated by both approaches are compared to each other and to experimental measurements made in a flume at the University of Caen or to published data (e.g. Roulund et al., 2005; Dargahi,1989). Then the model is applied in a real configuration on an area including the future offshore wind farm of Courseulles-sur-Mer. Four monopiles are represented in the model using both approaches and modifications of the hydrodynamics and sediment transport are assessed along a tidal cycle. Currents increase at the side edge of the monopile and decrease in front of and downstream the monopile. Turbulent kinetic

  4. Archetypal Analysis for Nominal Observations.

    PubMed

    Seth, Sohan; Eugster, Manuel J A

    2016-05-01

    Archetypal analysis is a popular exploratory tool that explains a set of observations as compositions of few 'pure' patterns. The standard formulation of archetypal analysis addresses this problem for real valued observations by finding the approximate convex hull. Recently, a probabilistic formulation has been suggested which extends this framework to other observation types such as binary and count. In this article we further extend this framework to address the general case of nominal observations which includes, for example, multiple-option questionnaires. We view archetypal analysis in a generative framework: this allows explicit control over choosing a suitable number of archetypes by assigning appropriate prior information, and finding efficient update rules using variational Bayes'. We demonstrate the efficacy of this approach extensively on simulated data, and three real world examples: Austrian guest survey dataset, German credit dataset, and SUN attribute image dataset.

  5. Observability transition in real networks

    NASA Astrophysics Data System (ADS)

    Yang, Yang; Radicchi, Filippo

    2016-09-01

    We consider the observability model in networks with arbitrary topologies. We introduce a system of coupled nonlinear equations, valid under the locally treelike ansatz, to describe the size of the largest observable cluster as a function of the fraction of directly observable nodes present in the network. We perform a systematic analysis on 95 real-world graphs and compare our theoretical predictions with numerical simulations of the observability model. Our method provides almost perfect predictions in the majority of the cases, even for networks with very large values of the clustering coefficient. Potential applications of our theory include the development of efficient and scalable algorithms for real-time surveillance of social networks, and monitoring of technological networks.

  6. Observations of Orionids from Bulgaria

    NASA Astrophysics Data System (ADS)

    Dimitrov, Todor; Velkov, Valentin

    2010-01-01

    Presented are results from visual observations of the Orionds and other showers carried out in Bulgaria. Radiant positions of the basic active showers are obtained. Recorded is a possible new radiant in ARI.

  7. Hinode Observes an Active Sun

    NASA Video Gallery

    The X-ray Telescope on the Japanese/NASA mission Hinode has been observing the full sun, nearly continuously, for an extended period. In this movie significant small-scale dynamic events can be obs...

  8. Voyager 2 Observes Energetic Electrons

    NASA Video Gallery

    This animation shows the Voyager 2 observations of energetic electrons. Voyager 2 detected a dramatic drop of the flux of electrons as it left the sector region. The intense flux came back as soon ...

  9. Archetypal Analysis for Nominal Observations.

    PubMed

    Seth, Sohan; Eugster, Manuel J A

    2016-05-01

    Archetypal analysis is a popular exploratory tool that explains a set of observations as compositions of few 'pure' patterns. The standard formulation of archetypal analysis addresses this problem for real valued observations by finding the approximate convex hull. Recently, a probabilistic formulation has been suggested which extends this framework to other observation types such as binary and count. In this article we further extend this framework to address the general case of nominal observations which includes, for example, multiple-option questionnaires. We view archetypal analysis in a generative framework: this allows explicit control over choosing a suitable number of archetypes by assigning appropriate prior information, and finding efficient update rules using variational Bayes'. We demonstrate the efficacy of this approach extensively on simulated data, and three real world examples: Austrian guest survey dataset, German credit dataset, and SUN attribute image dataset. PMID:27046837

  10. [Asteroidea, Echinoidea y Holothuroidea in shallow bottoms of Bahía de Loreto, Baja California Sur, Mexico].

    PubMed

    Holguin Quiñones, O; Wright López, H; Solís Marín, F

    2000-12-01

    To evaluate echinoderm distribution, abundance and density a double 50 m transect, with a side observation range of 2.5 m was used at each of 11 stations (bimonthly samplings, Aug. 1997-Febr. 1998). In Bahía de Loreto the Phylum Echinodermata consists of 26 taxa. The greatest mean abundance by transect and mean densities in order of importance for Echinoidea were: Echinometra vanbrunti (94.1 +/- 52.9 ind, 0.25 ind/m2), Centrostephanus coronatus (38.15 +/- 9.15 ind, 0.06 ind/m2), Tripneustes depressus (28.68 +/- 6.86 ind, 0.039 ind/m2), Eucidaris thouarsii (10.66 +/- 3.37 ind, 0.025 ind/m2) and Diadema mexicanum (11.75 +/- 4.92 ind, 0.023 ind/m2); for Asteroidea were: Phataria unifascialis, Mithrodia bradleyi and Acanthaster planci. Asteroidea was the dominant class with 12 species, followed by Echinoidea with ten and Holothuroidea was represented by four species. PMID:11487923

  11. Prevalence and risk factors for intestinal parasitic infections in a rural community in "consolación del sur" municipality, cuba.

    PubMed

    Pino Santos, A; Núñez Fernández, F A; Martínez Sánchez, R; Domenech Cañete, I; Rodríguez, M; Jeres Puebla, L; Rodríguez González, Z

    2014-08-01

    Intestinal parasites are very common infections worldwide and they are responsible for significant public health problems. The World Health Organization estimates that one-third of the world population is infected and some epidemiologic factors related to the transmission have been identified. The purpose of this investigation was to study the prevalence of intestinal parasitic infections in people living in the rural community of "El Canal", Consolación del Sur municipality and the association with some epidemiologic risk factors. All participants were subjected to three methods of parasitological examinations on the stool samples and by immunodiagnostic tests which allow the detection of excretory-secretory antigens of adults with Fasciola hepatica. The global prevalence rate of intestinal parasitic infections (IPIs) was 18%, and 16.7% for protozoan infections, while the rate of helminth infection was lower (5.3%) in the population studied. The univariate analysis identified three factors associated with intestinal pathogenic protozoan infections which include livestock work, drinking water from well\\river and eating unwashed fruits\\vegetables. The multivariate analysis using introduction test logistic regression ratified the association of these risk factors. Contrary to what have been published in the majority of Cuban studies carried out in rural places, a higher prevalence of protozoan than helminth infection was found. This discrepancy may be explained because the majority of the workers in this rural community were stock-breeders and they are not involved in other agricultural work. The identification of risk factors is important in order to design appropriate strategies for control of IPIs in communities. PMID:25429477

  12. High-resolution seismic-reflection and marine-magnetic data from offshore central California--San Gregorio to Point Sur

    USGS Publications Warehouse

    Sliter, Ray W.; Johnson, Samuel Y.; Watt, Janet T.; Scheirer, Daniel S.; Allwardt, Parker; Triezenberg, Peter J.

    2013-01-01

    The U.S. Geological Survey collected high-resolution seismic-reflection data on four surveys (S-N1-09-MB, S-15-10-NC, S-06-11-MB, and S-04-12-MB) and marine-magnetic data on one survey (S-06-11-MB) between 2009 and 2012, offshore of central California between San Gregorio and Point Sur. This work was supported in part by the California Seafloor Mapping Program. The survey areas span about 120 km of California's coast (including Monterey Bay). Most data were collected aboard the U.S. Geological Survey R/V Parke Snavely. Cumulatively, approximately 1,410 km of single-channel seismic-reflection data were acquired, mainly using a SIG 2mille minisparker. About 44 km of data were collected simultaneously using an EdgeTech Chirp 512. Subbottom acoustic penetration spanned tens to several hundreds of meters, variable by location. Marine magnetic data were collected on approximately 460 km of track lines (mainly in southern Monterey Bay) using a Geometrics G882 cesium-vapor marine magnetometer. This report includes maps and navigation files of the surveyed transects, linked to Google Earth™ software, as well as digital data files showing images of each transect in SEG-Y and JPEG formats. The images of bedrock, sediment deposits, and tectonic structure provide geologic information that is essential to hazard assessment, regional sediment management, and coastal and marine spatial planning at Federal, State and local levels, as well as to future research on the geomorphic, sedimentary, tectonic, and climatic record of central California.

  13. Explaining the appeal for immigrant men who have sex with men of a community-based rapid HIV-testing site in Montreal (Actuel sur Rue).

    PubMed

    Lessard, David; Lebouché, Bertrand; Engler, Kim; Thomas, Réjean; Machouf, Nimâ

    2015-01-01

    Immigrant men who have sex with men (MSM) are vulnerable to HIV. In the last decade, several rapid HIV-testing facilities targeting MSM have been established around the world and seem popular among immigrants. This study analyzes factors contributing to immigrant MSM's use of Actuel sur Rue (AsR), a community-based rapid HIV-testing site in Montreal's gay village, where 31% of clients are immigrants. From October 2013 to January 2014, AsR staff compiled a list of new clients born outside of Canada. With their consent, 40 immigrant MSM were reached among these new clients for a 15-minute phone survey entailing open-ended and multiple-choice questions. The survey sought immigrant MSM's reasons for visiting AsR; satisfaction with service and staff; and open comments. An inductive thematic analysis was conducted with the qualitative data, and descriptive statistics were produced with the quantitative data. The qualitative findings indicate that the main reasons for seeking an HIV test were a recent risk, routine testing, or being in a new relationship. Clients chose AsR mainly because it is easily accessible, service is fast or they heard about it from a friend. The quantitative findings indicate that rates of satisfaction were high (over 90% were satisfied about all aspects except for openings hours) and more than 80% felt comfortable while receiving services at AsR. Nevertheless, this study's findings have implications for improving services. They stress the importance of offering rapid yet comprehensive service and of taking into account immigrant MSM's concerns for confidentiality.

  14. [Spatial and biogeographic characterization of macroalgal assemblages from Bahía del Rincón, Baja California Sur, Mexico].

    PubMed

    Riosmena-Rodríguez, R; Hinojosa-Arango, G; López-Vivas, J M; León-Cisneros, K; Holguin-Acosta, E

    2005-01-01

    Macroalgal studies in Baja California Sur have dealt mainly with occurrence and seasonality, but some areas are poorly known even for these basic data. Bahia del Rincón-La Rivera is an important high-productivity fisheries area where coastal infrastructure development is under way. A spatial characterization of the marine flora from Bahia del Rincón-La Rivera was done by intensive sampling at different depths and localities with skin and SCUBA diving. At least 500 m2 were surveyed in each site. Additionally. quantitative sampling was done in ten random 25 cm2 quadrates per site. In the intertidal section, density and cover estimates were used. We also investigated the historical records and geographical affinities. A total of 72 species were identified (most were red algae: 62%). We found no general trend in the biogeographical affinities, which varied with each taxonomic group. Most brown algae species were tropical-endemic; red algae temperate-cosmopolite and green algae tropical-cosmopolite. In the spatial assemblage structure we found a high similarity between the intertidal areas, but a low similarity in shallow or deeper areas (3-5 m). This pattern was the same when we compared the abundance of the main species. We suggest that there are significant spatial differences in recruitment and development of the assemblages in relation to vertical distribution (depth) and position along the shore. There is a clear-cut Gelidium-Jania belt in the intertidal zone and a Padina-Dictyota belt below the low tide. Sporadic and year-round species occur in the intertidal zone, annual and perennial species below the low tide line. Sites differ in recruitment and this affects the abundance of other species (such as coraline and Caulerpa species). Temperature and sedimentation affect seasonality, but community structure is relatively constant throughout the year.

  15. Lignes directrices sur la prise en charge en soins primaires des céphalées chez l’adulte

    PubMed Central

    Becker, Werner J.; Findlay, Ted; Moga, Carmen; Scott, N. Ann; Harstall, Christa; Taenzer, Paul

    2015-01-01

    Résumé Objectif Accroître l’utilisation d’approches éclairées par des données probantes pour diagnostiquer, investiguer et traiter en soins primaires les céphalées des patients. Qualité des données Une recherche documentaire exhaustive a été effectuée pour trouver des lignes directrices et des révisions systématiques publiées entre janvier 2000 et mai 2011. La grille d’évaluation de la qualité des recommandations pour la pratique clinique AGREE a servi à l’analyse critique des lignes directrices. Les 6 guides de pratique clinique de la plus grande qualité ont servi de base dans le processus d’adaptation. Message principal Un groupe d’élaboration multidisciplinaire de professionnels des soins primaires ont formulé 91 recommandations précises à l’aide d’un processus consensuel. Les recommandations portent sur le diagnostic, l’investigation et la prise en charge de la migraine, de la céphalée de tension, de la céphalée due à une surmédication et de la céphalée vasculaire de Horton. Conclusion Un guide de pratique clinique adapté au contexte des soins de santé au Canada a été produit en suivant un processus d’adaptation de lignes directrices dans le but d’aider les professionnels de toutes les disciplines des soins primaires à dispenser des soins éclairés par des données probantes aux patients souffrant de céphalées.

  16. Elemental concentrations in different species of seaweeds from Loreto Bay, Baja California Sur, Mexico: implications for the geochemical control of metals in algal tissue.

    PubMed

    Sánchez-Rodríguez, I; Huerta-Diaz, M A; Choumiline, E; Holguín-Quiñones, O; Zertuche-González, J A

    2001-01-01

    Concentration levels of 21 elements were analyzed by instrumental neutron activation analysis (Rb, Cs, Ca, Sr, Ba, Sc, Cr, Fe, Co, Ni, Zn, Se, As, Sb, Th, U, Br, Hf, Ta, Zr, and Ag) in seven different seaweed species (Codium cuneatum, Sargassum sinicola, Padina durvillaei, Laurencia johnstonii, L. papillosa, Gracilaria pachidermatica and Hypnea pannosa), collected in a shallow coastal zone from Bahia de Loreto, Baja California Sur, Mexico. Measured concentrations in algal tissue spanned almost eight orders of magnitude (from 2.0 x 10(-3) microg g(-1) for Hf to 1.2 x 10(5) microg g(-1) for Ca). Ca was consistently the most abundant element in all analyzed seaweeds, followed by Fe and Sr. Brown algae showed a tendency to incorporate higher concentrations of elements than red and green algae. Additionally, there were significant linear correlations (P < 0.05 to P < 0.001) between a total of 76 different pairs of elements, some of them (e.g. Rb-Ni, Rb-Ag, Sc Cr, Sc-Fe, Sc Ni, Sc Hf, Cr Fe, Fe Ni, Fe-Hf and Ni-Th) highly correlated (r2 > 0.900). A significant correlation (r2 = 0.701, n = 18, P < 0.001) exists between our measurements in the tissue of algae and their corresponding average elemental concentrations in oceanic water from the North Pacific Ocean. Hence, overall elemental abundance in algal tissue apparently is controlled by the elemental abundance in oceanic water, whereas metabolic processes as well as environmental factors relevant to each region modify the final concentration of a given element in the body of a macroalgae.

  17. Cestodes of the blue shark, Prionace glauca (Linnaeus 1758), (Carcharhiniformes: Carcharhinidae), off the west coast of Baja California Sur, Mexico.

    PubMed

    Méndez, Oscar; Galván-Magaña, Felipe

    2016-01-01

    The cestode species recovered from the spiral intestines of 27 blue sharks (Prionace glauca) (Linnaeus, 1758) are reported from the western coast of Baja California Sur (BCS). The sampling was undertaken on a monthly basis from January 2003 to January 2004. The helminthological examination indicated the presence of four species of cestodes: Platybothrium auriculatum Yamaguti, 1952; Prosobothrium japonicum Yamaguti, 1934; Anthobothrium caseyi (Yamaguti, 1934) Ruhnke & Caira, 2009; and Paraorygmatobothrium prionacis (Yamaguti, 1934) Ruhnke, 1994. Of all the 27 sharks examined, 88.8% were infected with at least one cestode species. The most frequent species was P. auriculatum infecting 85% of the spiral intestines examined. In contrast the species with the highest mean intensity was P. prionacis (80.4 200). The species richness of cestodes in P. glauca is very similar in other regions of the world despite its wide distribution; however, this richness is low compared with other species of sharks within the same family. The feeding and host-specific are important factors that influence the parameters of infection of cestodes in this shark. On the west coast of BCS, Prionace glauca feeds mainly on red crab Pleuroncodes planipes Stimpson, 1860; squids Gonatus californiensis Young, 1972, Ancistrocheirus lesueurii (D'Orbigny, 1842), Haliphron atlanticus Steenstrup, 1861, and low proportion of fish teleosts as Merluccius productus (Ayres, 1855), Sardinops sp. Hubbs, 1929 and Scomber japonicus Houttuyn, 1872. We speculate that these prey could be involved as the second intermediate hosts of these cestodes, as in other members of these genera, although the life cycles of none are known. PMID:27394312

  18. Incidence of organochlorine pesticides and the health condition of nestling ospreys (Pandion haliaetus) at Laguna San Ignacio, a pristine area of Baja California Sur, Mexico.

    PubMed

    Rivera-Rodríguez, Laura B; Rodríguez-Estrella, Ricardo

    2011-01-01

    We identified and quantified organochlorine (OC) pesticide residues in the plasma of 28 osprey (Pandion haliaetus) nestlings from a dense population in Laguna San Ignacio, a pristine area of Baja California Sur, Mexico, during the 2001 breeding season. Sixteen OC pesticides were identified and quantified. α-, β-, δ- and γ-hexachlorocyclohexane, heptaclor, heptachlor epoxide, endosulfan I and II, endosulfan-sulfate, p,p'-DDE, p,p'-DDD, aldrin, dieldrin, endrin, endrin aldehyde, and endrin ketone were the OCs found in the plasma of nestlings, ranging from 0.002 to 6.856 pg/μl (parts per billion). No differences were found in the concentration of pesticides between genders (P > 0.05). In our work, the concentrations detected in the plasma were lower than those reported to be a threat for the species and that affect the survival and reproduction of birds. The presence of OC pesticides in the remote Laguna San Ignacio osprey population is an indication of the ubiquitous nature of these contaminants. OCs are apparently able to travel long distances from their source to the study area. A significant relationship between hemoglobin and mean corpuscular hemoglobin concentrations and OC concentrations were found suggesting that a potential effect on the health of chicks may exist in this osprey population caused by the OC, e.g. anemia. The total proteins were positively correlated with α-BHC, endosulfan I, and p,p'-DDD. It has been suggested that OC also affects competitive interactions and population status over the long term in vertebrate species, and our results could be used as reference information for comparison with other more exposed osprey populations. PMID:20949316

  19. Cestodes of the blue shark, Prionace glauca (Linnaeus 1758), (Carcharhiniformes: Carcharhinidae), off the west coast of Baja California Sur, Mexico.

    PubMed

    Méndez, Oscar; Galván-Magaña, Felipe

    2016-03-03

    The cestode species recovered from the spiral intestines of 27 blue sharks (Prionace glauca) (Linnaeus, 1758) are reported from the western coast of Baja California Sur (BCS). The sampling was undertaken on a monthly basis from January 2003 to January 2004. The helminthological examination indicated the presence of four species of cestodes: Platybothrium auriculatum Yamaguti, 1952; Prosobothrium japonicum Yamaguti, 1934; Anthobothrium caseyi (Yamaguti, 1934) Ruhnke & Caira, 2009; and Paraorygmatobothrium prionacis (Yamaguti, 1934) Ruhnke, 1994. Of all the 27 sharks examined, 88.8% were infected with at least one cestode species. The most frequent species was P. auriculatum infecting 85% of the spiral intestines examined. In contrast the species with the highest mean intensity was P. prionacis (80.4 200). The species richness of cestodes in P. glauca is very similar in other regions of the world despite its wide distribution; however, this richness is low compared with other species of sharks within the same family. The feeding and host-specific are important factors that influence the parameters of infection of cestodes in this shark. On the west coast of BCS, Prionace glauca feeds mainly on red crab Pleuroncodes planipes Stimpson, 1860; squids Gonatus californiensis Young, 1972, Ancistrocheirus lesueurii (D'Orbigny, 1842), Haliphron atlanticus Steenstrup, 1861, and low proportion of fish teleosts as Merluccius productus (Ayres, 1855), Sardinops sp. Hubbs, 1929 and Scomber japonicus Houttuyn, 1872. We speculate that these prey could be involved as the second intermediate hosts of these cestodes, as in other members of these genera, although the life cycles of none are known.

  20. Capillary electrophoresis finger print technique (CE-SSCP): an alternative tool for the monitoring activities of HAB species in Baja California Sur Costal.

    PubMed

    Herrera-Sepúlveda, Angélica; Hernandez-Saavedra, Norma Y; Medlin, Linda K; West, Nyree

    2013-10-01

    In Mexican waters, there is no a formal and well-established monitoring program of harmful algal blooms (HAB) events. Until now, most of the work has been focused on the characterization of organisms present in certain communities. Therefore, the development of new techniques for the rapid detection of HAB species is necessary. Capillary electrophoresis finger print technique (CE-SSCP) is a fingerprinting technique based on the identification of different conformers dependent of its base composition. This technique, coupled with capillary electrophoresis, has been used to compare and identify different conformers. The aim of this study was to determine if CE-SSCP analysis of ribosomal RNA (rRNA) gene fragments could be used for a rapid identification of toxic and harmful HAB species to improve monitoring activities along the coasts of Baja California Sur, Mexico.Three different highly variable regions of the 18S and 28S rRNA genes were chosen and their suitability for the discrimination of different dinoflagellate species was assessed by CE-SSCP.The CE-SSCP results obtained for the LSU D7 fragment has demonstrated that this technique with this gene region could be useful for the identification of the ten dinoflagellates species of different genera.We have shown that this method can be used to discriminate species and the next step will be to apply it to natural samples to achieve our goal of molecular monitoring for toxic algae in Mexican waters. This strategy will offer an option to improve an early warning system of HAB events for coastal BCS, allowing the possible implementation of mitigation strategies. A monitoring program of HAB species using molecular methods will permit the analysis of several samples in a short period of time, without the pressure of counting with a taxonomic expert in phytoplankton taxonomy. PMID:22744160