Sample records for proc fla state

  1. Chlamydomonas Kinesin-II–dependent Intraflagellar Transport (IFT): IFT Particles Contain Proteins Required for Ciliary Assembly in Caenorhabditis elegans Sensory Neurons

    PubMed Central

    Cole, Douglas G.; Diener, Dennis R.; Himelblau, Amy L.; Beech, Peter L.; Fuster, Jason C.; Rosenbaum, Joel L.

    1998-01-01

    We previously described a kinesin-dependent movement of particles in the flagella of Chlamydomonas reinhardtii called intraflagellar transport (IFT) (Kozminski, K.G., K.A. Johnson, P. Forscher, and J.L. Rosenbaum. 1993. Proc. Natl. Acad. Sci. USA. 90:5519–5523). When IFT is inhibited by inactivation of a kinesin, FLA10, in the temperature-sensitive mutant, fla10, existing flagella resorb and new flagella cannot be assembled. We report here that: (a) the IFT-associated FLA10 protein is a subunit of a heterotrimeric kinesin; (b) IFT particles are composed of 15 polypeptides comprising two large complexes; (c) the FLA10 kinesin-II and IFT particle polypeptides, in addition to being found in flagella, are highly concentrated around the flagellar basal bodies; and, (d) mutations affecting homologs of two of the IFT particle polypeptides in Caenorhabditis elegans result in defects in the sensory cilia located on the dendritic processes of sensory neurons. In the accompanying report by Pazour, G.J., C.G. Wilkerson, and G.B. Witman (1998. J. Cell Biol. 141:979–992), a Chlamydomonas mutant (fla14) is described in which only the retrograde transport of IFT particles is disrupted, resulting in assembly-defective flagella filled with an excess of IFT particles. This microtubule- dependent transport process, IFT, defined by mutants in both the anterograde (fla10) and retrograde (fla14) transport of isolable particles, is probably essential for the maintenance and assembly of all eukaryotic motile flagella and nonmotile sensory cilia. PMID:9585417

  2. High-Performance Solid-State and Fiber Lasers Controlled by Volume Bragg Gratings

    DTIC Science & Technology

    2013-09-01

    Glebov: Proc. SPIE 8237 (2012) 823705. 12） I. Divliansky, D. Ott, B. Anderson, G. Venus, and L. Glebov: To be published in Opt. Express. 13） A. Jain...B. Anderson, D. Drachenberg, V. Rotar, G. Venus, and L. Glebov: Proc. SPIE 8237 (2012) 823705. 47） B. Anderson, S. Kaim, G. B. Venus, J. Lumeau, V

  3. Proceedings of the Conference on the Design of Experiments in Army Research Development and Testing (27th) Held at The McKimmon Center for Continuing Education, North Carolina State University, Raleigh, North Carolina on 21-23 October 1981

    DTIC Science & Technology

    1982-06-01

    of states and a class of cascade processes. Proc. Cambridge Phil . Soc. 47, 77-85. Foster, F. G. (1952). On Markov chains with an enumerable infinity of...states. Proc. Cambridge Phil . Soc. 48, 587-591. Foster, F. G. (1953). On the stochastic matrices associated with certain queuing processes. Ann. Math...Frawley (1973), Li and Schucany (1975), Schucany and Beckett (1976), and Hollander and Sethurann (1978). The Schucany-Frawley-Li test is based on the

  4. Solid State Research

    DTIC Science & Technology

    1988-11-15

    Reduction of Intermodulation L.M. Johnson Opt. Lett. 13, 928 (1988) Distortion in Interferometric H.V. Roussell Optical Modulators * Author not at Lincoln...Engineering V, Proc. Niobate Interferometric Modulators SPIE 835, 29 (1988), DTIC AD-A198029 7553 Advanced Device Fabrication with W.D. Goodhue Proc...Colorado, 3 October 1988 7741 B Integrated-Optical Interferometric L.M. Johnson 2 X 2 Switches H.V.Roussell 7927B Free-Space Optical Interconnects

  5. Reliability Evaluation of Computer Systems.

    DTIC Science & Technology

    1981-01-01

    algorithms in hardware is not restricted by the designs of particular circuits. Applications could be made in new computer architectures; one candidate...pp. 137-148, IEEE, Chicago, Illinois, September 1963. (With J.F. Wakerly ) "Design of Low-Cost General-Purpose Self- Diagnosing Computers," Proc...34 Proc., IEEE Int’l Solid-State Circuits Conference, Philadelphia, Pennsylvania, February 16-18, 1977. (With J.F. Wakerly ) "Microcomputers in the

  6. A State-of-the-Art Assessment of Automatic Name Placement.

    DTIC Science & Technology

    1986-08-01

    develop an automatic name placement system. 11 Balodis, M., "Positioning of typography on maps," Proc. ACSM Pall Con- vention, Salt Lake City, Utah, Sept...1983, pp. 28-44. This article deals with the selection of typography for maps. It describes psycho-visual experiments with groups of individuals to...Polytechnic Institute, Troy, NY 12181, May 1984. (Also available as Tech. Rept. IPL-TR-063.) SBalodis, M., "Positioning of typography on maps," Proc

  7. Time-dependent and time-independent approaches to study effects of degenerate electronic states

    NASA Astrophysics Data System (ADS)

    Baer, Michael; Yahalom, Asher; Englman, Robert

    1998-10-01

    Two types of phases are discussed in this article: (1) The topological phase as introduced by Berry [Proc. R. Soc. London, Ser. A 392, 45(1984)] and Aharonov and Anandan [Phys. Rev. Lett. 58, 1593 (1987)] and (2) the Longuet-Higgins phase [Proc. R. Soc. London, Ser. A 344, 147 (1975)]. The two types of phases have a common origin, namely the multivaluedness of the electronic adiabatic basis, a phenomenon associated with the existence of a degeneracy in configuration space. It will be shown, by studying an electronic model Hamiltonian that arises from a two-state approximation to the Mathieu equation, that the two phases differ from each other substantially, coinciding only in the adiabatic limit upon completion of a cycle.

  8. System Synthesis for Polymorphous Computing Architectures

    DTIC Science & Technology

    2002-02-01

    G H F Proc 5 : 4 : 3 11 1 Figure 3. Self-timed execution. D C B F G H E D B H EA CG F D C B F G H E D B H EA CG F AProc 1 Proc 2...first-iteration actors denoted by T. D B H E CG F D C B F G H E D B H EA CG F A 18 T T T T Proc 3 Proc 4 Proc 5 Proc 1 Proc 2 1 T⁄ T trmin30 ture-mirror...Phase1Algo( , ) = transientReduction( ) Output T G S′ S G T S′ S S′ Figure 11. Pseudocode to find

  9. Research Directions in Database Security, II

    DTIC Science & Technology

    1990-11-01

    WILLIAMS Burke Ct 286 WOLCOTT 9th Rd 795 WOOD 25th St 520 YANCEY Motley St 398 ZUZACK Arden Rd LDV> : The style of the prototype is such that the...WOLCOTT Fin Clk YANCEY Dept Mgr ZUZACK Proc Anal LDV> ;RR3: S (sortrel (project (njoin (project employee-base ’(Department Employee-Name Employee-Num...Proc Anal PROC MAHONEY Secy PROC YANCEY Dept Mgr PROC ZUZACK Proc Anal SEC BRIMER DMSO SEC FALBO Secy SEC HILL Dept Mgr SEC MITCHELL Ast DBSO SEC THOMAS

  10. A Review of PROC IRT in SAS

    ERIC Educational Resources Information Center

    Choi, Jinnie

    2017-01-01

    This article reviews PROC IRT, which was added to Statistical Analysis Software in 2014. We provide an introductory overview of a free version of SAS, describe what PROC IRT offers for item response theory (IRT) analysis and how one can use PROC IRT, and discuss how other SAS macros and procedures may compensate the IRT functionalities of PROC IRT.

  11. 3 CFR 9007 - Proclamation 9007 of August 30, 2013. National Childhood Obesity Awareness Month, 2013

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Childhood Obesity Awareness Month, 2013 9007 Proclamation 9007 Presidential Documents Proclamations Proclamation 9007 of August 30, 2013 Proc. 9007 National Childhood Obesity Awareness Month, 2013By the President of the United States of America A Proclamation In the United States, obesity affects millions of...

  12. The chimeric VirA-tar receptor protein is locked into a highly responsive state.

    PubMed Central

    Turk, S C; van Lange, R P; Sonneveld, E; Hooykaas, P J

    1993-01-01

    The wild-type VirA protein is known to be responsive not only to phenolic compounds but also to sugars via the ChvE protein (G. A. Cangelosi, R. G. Ankenbauer, and E. W. Nester, Proc. Natl. Acad. Sci. USA 87:6708-6712, 1990, and N. Shimoda, A. Toyoda-Yamamoto, J. Nagamine, S. Usami, M. Katayama, Y. Sakagami, and Y. Machida, Proc. Natl. Acad. Sci. USA 87:6684-6688, 1990). It is shown here that the mutant VirA(Ser-44, Arg-45) protein and the chimeric VirA-Tar protein are no longer responsive to sugars and the ChvE protein. However, whereas the chimeric VirA-Tar protein was found to be locked in a highly responsive state, the VirA(Ser-44, Arg-45) mutant protein appeared to be locked in a low responsive state. This difference turned out to be important for tumorigenicity of the host strains in virulence assays on Kalanchoë daigremontiana. Images PMID:8366057

  13. 3 CFR 9067 - Proclamation 9067 of December 5, 2013. Death of Nelson Mandela

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 5, 2013 Proc. 9067 Death of Nelson MandelaBy the President of the United States of America A... Nelson Mandela's memory. He left behind a South Africa that is free and at peace with itself—a close... Constitution and laws of the United States of America, I hereby order that the flag of the United States shall...

  14. Optimization-based methods for road image registration

    DOT National Transportation Integrated Search

    2008-02-01

    A number of transportation agencies are now relying on direct imaging for monitoring and cataloguing the state of their roadway systems. Images provide objective information to characterize the pavement as well as roadside hardware. The tasks of proc...

  15. 75 FR 69741 - Proposed Collection; Comment Request for Rev. Proc. 2007-99 (RP-127367-07), 9100 Relief Under...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-15

    .... Proc. 2007-99 (RP- 127367-07), 9100 Relief Under Sections 897 and 1445 AGENCY: Internal Revenue Service...)). Currently, the IRS is soliciting comments concerning Rev. Proc. 2007-99 (RP-127367-07), 9100 Relief Under...: Rev. Proc. 2007-99 (RP-127367-07), 9100 Relief Under Sections 897 and 1445. OMB Number: 1545-2098...

  16. The gap of the area-weighted Motzkin spin chain is exponentially small

    NASA Astrophysics Data System (ADS)

    Levine, Lionel; Movassagh, Ramis

    2017-06-01

    We prove that the energy gap of the model proposed by Zhang et al (2016 arXiv:1606.07795) is exponentially small in the square of the system size. In Movassagh and Shor (2016 Proc. Natl Acad. Sci. USA) a class of exactly solvable quantum spin chain models was proposed that have integer spins (s), with a nearest neighbors Hamiltonian, and a unique ground state. The ground state can be seen as a uniform superposition of all s-colored Motzkin walks. The half-chain entanglement entropy provably violates the area law by a square root factor in the system’s size (˜\\sqrt{n} ) for s  >  1. For s  =  1, the violation is logarithmic (Bravyi et al 2012 Phys. Rev. Lett. 109 207202). Moreover in Movassagh and Shor (2016 Proc. Natl Acad. Sci. USA) it was proved that the gap vanishes polynomially and is O(n -c ) with c≥slant2 . Recently, a deformation of Movassagh and Shor (2016 Proc. Natl Acad. Sci. USA), which we call ‘weighted Motzkin quantum spin chain’ was proposed Zhang et al (2016 arXiv:1606.07795). This model has a unique ground state that is a superposition of the s-colored Motzkin walks weighted by tarea\\{Motzkin walk\\} with t  >  1. The most surprising feature of this model is that it violates the area law by a factor of n. Here we prove that the gap of this model is upper bounded by 8ns t-n2/3 for t  >  1 and s  >  1.

  17. Performance Analysis of Polymorphous Computing Architectures

    DTIC Science & Technology

    2001-01-01

    G H F Proc 5 : 4 : 3 11 1 Figure 3. Self-timed execution. D C B F G H E D B H EA CG...F D C B F G H E D B H EA CG F AProc 1 Proc 2 Proc 3 Proc 4 Proc 5 185 cution pattern when the application graph in Figure 2 is executed in a self...transform, a quadra- E Figure 10. Self-timed execution with first-iteration actors denoted by T. D B H E CG F D C B F G H E D B H EA CG F A 18 T T T

  18. 3 CFR 8752 - Proclamation 8752 of November 8, 2011. World Freedom Day, 2011

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ..., 2011 Proc. 8752 World Freedom Day, 2011By the President of the United States of America A Proclamation... ourselves at a crossroads of history as a wave of democratic movements sweeps away oppressive dictatorships... United States of America, by virtue of the authority vested in me by the Constitution and the laws of the...

  19. 3 CFR 8985 - Proclamation 8985 of May 21, 2013. National Maritime Day, 2013

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 3 The President 1 2014-01-01 2014-01-01 false Proclamation 8985 of May 21, 2013. National Maritime..., 2013 Proc. 8985 National Maritime Day, 2013By the President of the United States of America A... extraordinary things as members of the United States Merchant Marine. When the idea of America depended on the...

  20. 3 CFR 9055 - Proclamation 9055 of November 5, 2013. Veterans Day, 2013

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... marking the 60th anniversary of the Korean War Armistice, we resolved that in the United States of America... 3 The President 1 2014-01-01 2014-01-01 false Proclamation 9055 of November 5, 2013. Veterans Day... Proc. 9055 Veterans Day, 2013By the President of the United States of America A Proclamation On...

  1. 3 CFR 8737 - Proclamation 8737 of October 14, 2011. National Character Counts Week, 2011

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... October 14, 2011 Proc. 8737 National Character Counts Week, 2011By the President of the United States of... is imperative that we create a climate of acceptance and compassion in our schools and communities... States of America, by virtue of the authority vested in me by the Constitution and the laws of the United...

  2. CHLOROLYSIS APPLIED TO THE CONVERSION OF CHLOROCARBON RESIDUES

    EPA Science Inventory

    This program was initiated with the objective of determining the technical feasibility and economic viability of eliminating, within the United States, the discharge of large quantities of chlorocarbon residues which are harmful to the environment through the use of a German proc...

  3. Construction of even and odd combinations of Morse-like coherent states

    NASA Astrophysics Data System (ADS)

    Récamier, José; Jáuregui, Rocio

    2003-06-01

    In this work we construct approximate coherent states for the Morse potential using a method inspired by the f-oscillator formalism (Man'ko et al 1996 Proc. 4th Wigner Symp. ed M Natig, Atakishiyev, T H Seligman and K B Wolf (Singapore: World Scientific) p 421). We make even and odd combinations of these states and evaluate the temporal evolution of the position operator and its dispersion as a function of time when the states evolve under a nonlinear Morse Hamiltonian.

  4. SAS FORMATS: USES AND ABUSES

    EPA Science Inventory

    SAS formats are a very powerful tool. They allow you to display the data in a more readable manner without modifying the data. They can also be used to group data into categories for use in various procedures like PROC FREQ, PROC TTEST, and PROC MEANS (as a class variable). ...

  5. SAS FORMATS: USES AND ABUSES

    EPA Science Inventory

    SAS formats are a very powerful tool. They allow you to display the data in a more readable manner without modifying it. Formats can also be used to group data into categories for use in various procedures like PROC FREQ, PROC TTEST, and PROC MEANS (as a class variable). As ...

  6. Foundations of Nuclear Geophysics

    NASA Astrophysics Data System (ADS)

    Herndon, J. M.; Hollenbach, D. F.

    2002-05-01

    Herndon suggested that the inner core of the Earth consists, not of partially crystallized iron metal, but of nickel silicide. He has shown by fundamental mass ratios that i) the Earth as a whole, especially the inner 82%, has a state of oxidation like primitive enstatite chondrites, and ii) the lower mantle and core are similar in composition to the Abee enstatite chondrite. By analogy with Abee data, CaS and MgS precipitates from the core are expected to collect at the core-mantle boundary and, significantly, a major fraction of the actinides are expected to precipitate from the core and to collect at the center of the Earth. Herndon demonstrated the feasibility of a nuclear fission reactor at the center of the Earth as the energy source for the geomagnetic field and described a natural mechanism that would lead to variations in energy production and thus variations in the geomagnetic field. Hollenbach and Herndon produced numerical simulations of the operation of the geo-reactor over the lifetime of the Earth using the state-of-the-art, validated, industry standard SCALE code package developed at Oak Ridge National Laboratory. The results clearly demonstrate that such a geo-reactor would i) function as a fast-neutron breeder reactor; ii) under appropriate conditions, operate over the entire period of geologic time; iii) function in such a manner as to yield variable and/or intermittent output; iv) generate energy at levels in the range generally accepted by the geophysics community; and, v) produce He-3 and He-4 in ratios that are in the range observed from deep-mantle sources. Deep-source He-3, the authors submit, is evidence of in-core sustained nuclear fission, rather than the out-gassing of primordial He-3; which in turn is evidence of large amounts of uranium residing in the Earth's core; which in turn is evidence that the core has a state of oxidation like the corresponding matter in primitive enstatite chondrites. The factors affecting He-3/He-4 ratios, their causes and implications, will be discussed in the presentation. Also, the current state of investigations into additional deep-Earth nuclear fission signatures will be presented. References: J. M. Herndon, Proc. R. Roc. London, Ser. A, 368 (1979) 495; J. Geomagn. Geoelectr. 45 (1993) 423; Proc. R. Soc. London, Ser. A, 445 (1994) 453; Proc. Nat. Acad. Sci. (USA) 93 (1996) 646. Hollenbach, D. F. and J. M. Herndon, Proc. Nat. Acad. Sci. (USA) 98 (2001) 11085.

  7. SAS FORMATS: USES AND ABUSES

    EPA Science Inventory

    SAS formats are a very powerful tool. They allow you to display the data in a more readable manner without modifying it. Formats can also be used to group data into categories for use in various procedures like PROC FREQ, PROC TTEST, and PROC MEANS (as a class variable). As w...

  8. 3 CFR 8591 - Proclamation 8591 of October 29, 2010. National Alzheimer's Disease Awareness Month, 2010

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Alzheimer's Disease Awareness Month, 2010 8591 Proclamation 8591 Presidential Documents Proclamations Proclamation 8591 of October 29, 2010 Proc. 8591 National Alzheimer's Disease Awareness Month, 2010By the President of the United States of America A Proclamation Alzheimer’s disease tragically robs individuals of...

  9. 3 CFR 8852 - Proclamation 8852 of August 31, 2012. National Childhood Obesity Awareness Month, 2012

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Childhood Obesity Awareness Month, 2012 8852 Proclamation 8852 Presidential Documents Proclamations Proclamation 8852 of August 31, 2012 Proc. 8852 National Childhood Obesity Awareness Month, 2012By the President of the United States of America A Proclamation Over the past several decades, childhood obesity...

  10. 3 CFR 8342 - Proclamation 8342 of January 16, 2009. To Suspend Entry as Immigrants and Nonimmigrants of...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Entry as Immigrants and Nonimmigrants of Foreign Government Officials Responsible for Failing To Combat... January 16, 2009 Proc. 8342 To Suspend Entry as Immigrants and Nonimmigrants of Foreign Government... into the United States, as immigrants or nonimmigrants, of certain senior government officials...

  11. A Price To Pay for Relaxed Substrate Specificity: A Comparative Kinetic Analysis of the Class II Lanthipeptide Synthetases ProcM and HalM2

    PubMed Central

    2015-01-01

    Lanthipeptides are a class of ribosomally synthesized and posttranslationally modified peptide natural products (RiPPs) that typically harbor multiple intramolecular thioether linkages. For class II lanthipeptides, these cross-links are installed in a multistep reaction pathway by a single enzyme (LanM). The multifunctional nature of LanMs and the manipulability of their genetically encoded peptide substrates (LanAs) make LanM/LanA systems promising targets for the engineering of new antibacterial compounds. Here, we report the development of a semiquantitative mass spectrometry-based assay for kinetic characterization of LanM-catalyzed reactions. The assay was used to conduct a comparative kinetic analysis of two LanM enzymes (HalM2 and ProcM) that exhibit drastically different substrate selectivity. Numerical simulation of the kinetic data was used to develop models for the multistep HalM2- and ProcM-catalyzed reactions. These models illustrate that HalM2 and ProcM have markedly different catalytic efficiencies for the various reactions they catalyze. HalM2, which is responsible for the biosynthesis of a single compound (the Halβ subunit of the lantibiotic haloduracin), catalyzes reactions with higher catalytic efficiency than ProcM, which modifies 29 different ProcA precursor peptides during prochlorosin biosynthesis. In particular, the rates of thioether ring formation are drastically reduced in ProcM, likely because this enzyme is charged with installing a variety of lanthipeptide ring architectures in its prochlorosin products. Thus, ProcM appears to pay a kinetic price for its relaxed substrate specificity. In addition, our kinetic models suggest that conformational sampling of the LanM/LanA Michaelis complex could play an important role in the kinetics of LanA maturation. PMID:25409537

  12. United States Air Force Summary, First Edition

    DTIC Science & Technology

    1976-01-01

    Montoya, Joseph M. (N. Max.) Inouye, DanIel K. (Hawaii) Hollings, &nest F. (S.C.) Bayh, Birch (Ind.) Eagleton, ThomasF. (Mo.) Chiles, Lawton (Fla...0334 REF4 AF/ACBM~350 HOUSE APPROPRIATIONS. COMMITTEE Democrats Mohon, George H. (Tex.) Chairmm Whitten, Jamie L. (Miss.) Sikes, RobertL. F. (Fla...S.C.) Bellmon, Henry t., (okle.) Dole, Bob (Kans.) Beall, J. Glenn, Jr. (MD) ~ublicans Cranston, Alan (Cal.) Chiles, lawton (Fla.) Abourezk, James

  13. REddyProc: Enabling researchers to process Eddy-Covariance data

    NASA Astrophysics Data System (ADS)

    Wutzler, Thomas; Moffat, Antje; Migliavacca, Mirco; Knauer, Jürgen; Menzer, Olaf; Sickel, Kerstin; Reichstein, Markus

    2017-04-01

    Analysing Eddy-Covariance measurements involves extensive processing, which puts technical labour to researchers. There is a need to overcome difficulties in data processing associated with deploying, adapting and using existing software and online tools. We tackled that need by developing the REddyProc package in the open source cross-platform language R that provides standard processing routines for reading half-hourly files from different formats, including from the recently released FLUXNET 2015 dataset, uStar threshold estimation and associated uncertainty, gap-filling, flux partitioning (both night-time or daytime based), and visualization of results. Although different in some features, the package mimics the online tool that has been extensively used by many users and site Principal Investigators (PIs) in the last years, and available on the website of the Max Planck Institute for Biogeochemistry. Generally, REddyProc results are statistically equal to results based on the state-of the art tools. The provided routines can be easily installed, configured, used, and integrated with further analysis. Hence the eddy covariance community will benefit from using the provided package allowing easier integration of standard processing with extended analysis. This complements activities by AmeriFlux, ICOS, NEON, and other regional networks for developing codes for standardized data processing of multiple sites in FLUXNET.

  14. An Implementation in Pascal: Translation of Prolog into Pascal.

    DTIC Science & Technology

    1985-06-01

    for i:=1 to px do begin ifr (proc .i..relativity=O) then continue; if proc .. ) .ptype=6) hen continue;if (proc (...abegin<>O) then continue; passname...forj:=reitorn do if (j0) then continue; if (par (.>) ppe <>1) then continue; if (par .. .namie<>par(.i.).name) parle nO ype:par C.’ ntype; par Inblnd

  15. 3 CFR 8684 - Proclamation 8684 of May 31, 2011. African-American Music Appreciation Month, 2011

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Music Appreciation Month, 2011 8684 Proclamation 8684 Presidential Documents Proclamations Proclamation 8684 of May 31, 2011 Proc. 8684 African-American Music Appreciation Month, 2011By the President of the United States of America A Proclamation The music of our Nation has always spoken to the condition of our...

  16. 3 CFR 8527 - Proclamation 8527 of May 28, 2010. African-American Music Appreciation Month, 2010

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Music Appreciation Month, 2010 8527 Proclamation 8527 Presidential Documents Proclamations Proclamation 8527 of May 28, 2010 Proc. 8527 African-American Music Appreciation Month, 2010By the President of the United States of America A Proclamation Music can tell a story, assuage our sorrows, provide blessing and...

  17. 3 CFR 8774 - Proclamation 8774 of January 13, 2012. Religious Freedom Day, 2012

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 3 The President 1 2013-01-01 2013-01-01 false Proclamation 8774 of January 13, 2012. Religious... 13, 2012 Proc. 8774 Religious Freedom Day, 2012By the President of the United States of America A... religious freedom. Hailing from diverse backgrounds and faiths, countless settlers have shared a simple...

  18. 3 CFR 8792 - Proclamation 8792 of April 2, 2012. National Donate Life Month, 2012

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... National Donate Life Month, we reflect on that essential quality and recommit to saving lives through organ... Life Month, 2012 8792 Proclamation 8792 Presidential Documents Proclamations Proclamation 8792 of April 2, 2012 Proc. 8792 National Donate Life Month, 2012By the President of the United States of America...

  19. Internal erosion during soil pipeflow: state of science for experimental and numerical analysis

    USDA-ARS?s Scientific Manuscript database

    Many field observations have lead to speculation on the role of piping in embankment failures, landslides, and gully erosion. However, there has not been a consensus on the subsurface flow and erosion processes involved and inconsistent use of terms have exasperated the problem. One such piping proc...

  20. 3 CFR 8407 - Proclamation 8407 of August 31, 2009. National Ovarian Cancer Awareness Month, 2009

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Ovarian Cancer Awareness Month, 2009 8407 Proclamation 8407 Presidential Documents Proclamations Proclamation 8407 of August 31, 2009 Proc. 8407 National Ovarian Cancer Awareness Month, 2009By the President of the United States of America A Proclamation Ovarian cancer remains the leading cause of death from...

  1. 3 CFR 8462 - Proclamation 8462 of December 2, 2009. International Day of Persons With Disabilities, 2009

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Day of Persons With Disabilities, 2009 8462 Proclamation 8462 Presidential Documents Proclamations Proclamation 8462 of December 2, 2009 Proc. 8462 International Day of Persons With Disabilities, 2009By the... commitment to human rights and fundamental freedoms for persons with disabilities, the United States became a...

  2. 3 CFR 8702 - Proclamation 8702 of August 31, 2011. National Childhood Obesity Awareness Month, 2011

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Childhood Obesity Awareness Month, 2011 8702 Proclamation 8702 Presidential Documents Proclamations Proclamation 8702 of August 31, 2011 Proc. 8702 National Childhood Obesity Awareness Month, 2011By the President of the United States of America A Proclamation Since the 1970s, the rate of childhood obesity in...

  3. 3 CFR 8338 - Proclamation 8338 of January 13, 2009. Religious Freedom Day, 2009

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Freedom Day, 2009 8338 Proclamation 8338 Presidential Documents Proclamations Proclamation 8338 of January 13, 2009 Proc. 8338 Religious Freedom Day, 2009By the President of the United States of America A Proclamation Religious freedom is the foundation of a healthy and hopeful society. On Religious Freedom Day, we...

  4. 3 CFR 8605 - Proclamation 8605 of November 19, 2010. National Farm-City Week, 2010

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Farm-City Week, 2010 8605 Proclamation 8605 Presidential Documents Proclamations Proclamation 8605 of November 19, 2010 Proc. 8605 National Farm-City Week, 2010By the President of the United States of America... sustainable way of life for future generations. During National Farm-City Week, we recognize the myriad...

  5. 3 CFR 8515 - Proclamation 8515 of May 6, 2010. Military Spouse Appreciation Day, 2010

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... uniform and their families. They are America’s greatest military asset, and my Administration is committed..., 2010 Proc. 8515 Military Spouse Appreciation Day, 2010By the President of the United States of America... Nation’s servicemembers. At the heart of our Armed Forces, servicemembers' spouses keep our military...

  6. 3 CFR 8375 - Proclamation 8375 of May 8, 2009. Military Spouse Day, 2009

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Proc. 8375 Military Spouse Day, 2009By the President of the United States of America A Proclamation Military spouses share the sacrifices of service with our Nation's men and women in uniform. As members of... household finances to comforting children impacted by a military parent's absence, military spouses take on...

  7. 3 CFR 8422 - Proclamation 8422 of September 25, 2009. Gold Star Mother's and Families' Day, 2009

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Mother's and Families' Day, 2009 8422 Proclamation 8422 Presidential Documents Proclamations Proclamation 8422 of September 25, 2009 Proc. 8422 Gold Star Mother's and Families' Day, 2009By the President of the United States of America A Proclamation The sacrifices of our military servicemembers are etched in the...

  8. 3 CFR 9025 - Proclamation 9025 of September 26, 2013. Gold Star Mother's and Family's Day, 2013

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Mother's and Family's Day, 2013 9025 Proclamation 9025 Presidential Documents Proclamations Proclamation 9025 of September 26, 2013 Proc. 9025 Gold Star Mother's and Family's Day, 2013By the President of the United States of America A Proclamation In our city centers and our bustling parks, monuments stand...

  9. 3 CFR 8976 - Proclamation 8976 of May 9, 2013. Military Spouse Appreciation Day, 2013

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... wounded warriors. America's military spouses are at the core of our Armed Forces, and on Military Spouse..., 2013 Proc. 8976 Military Spouse Appreciation Day, 2013By the President of the United States of America... for military homeowners. Through First Lady Michelle Obama and Dr. Jill Biden's Joining Forces...

  10. 3 CFR 8678 - Proclamation 8678 of May 18, 2011. National Maritime Day, 2011

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... citizens around the world. On National Maritime Day, we honor their invaluable contributions to America’s... of our transportation system. Last year, my Administration implemented “America’s Marine Highway..., 2011 Proc. 8678 National Maritime Day, 2011By the President of the United States of America A...

  11. 3 CFR 8526 - Proclamation 8526 of May 20, 2010. National Maritime Day, 2010

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... ships and seafarers to our economic and national security. Since 1775, America’s maritime fleet has... their contributions to America’s leadership in the global marketplace, and to our security. Civilian..., 2010 Proc. 8526 National Maritime Day, 2010By the President of the United States of America A...

  12. 3 CFR 8649 - Proclamation 8649 of April 7, 2011. National Volunteer Week, 2011

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7, 2011 Proc. 8649 National Volunteer Week, 2011By the President of the United States of America A Proclamation America's story has been marked by the service of volunteers. Generations of selfless individuals... caring for older Americans to supporting our veterans and military families and rebuilding after...

  13. 3 CFR 8669 - Proclamation 8669 of May 5, 2011. Military Spouse Appreciation Day, 2011

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ..., Strengthening our Military Families: Meeting America’s Commitment, which marshaled resources from across our..., 2011 Proc. 8669 Military Spouse Appreciation Day, 2011By the President of the United States of America... protect and defend our great Nation every day. Across America and around the world, military spouses serve...

  14. 3 CFR 8832 - Proclamation 8832 of June 1, 2012. African-American Music Appreciation Month, 2012

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Music Appreciation Month, 2012 8832 Proclamation 8832 Presidential Documents Proclamations Proclamation 8832 of June 1, 2012 Proc. 8832 African-American Music Appreciation Month, 2012By the President of the United States of America A Proclamation As a long-cherished piece of American culture, music offers a...

  15. 3 CFR 9010 - Proclamation 9010 of August 30, 2013. National Prostate Cancer Awareness Month, 2013

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Prostate Cancer Awareness Month, 2013 9010 Proclamation 9010 Presidential Documents Proclamations Proclamation 9010 of August 30, 2013 Proc. 9010 National Prostate Cancer Awareness Month, 2013By the President of the United States of America A Proclamation Among American men, prostate cancer is both the second...

  16. 3 CFR 8855 - Proclamation 8855 of August 31, 2012. National Prostate Cancer Awareness Month, 2012

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Prostate Cancer Awareness Month, 2012 8855 Proclamation 8855 Presidential Documents Proclamations Proclamation 8855 of August 31, 2012 Proc. 8855 National Prostate Cancer Awareness Month, 2012By the President of the United States of America A Proclamation Prostate cancer is among the most common cancers for...

  17. 3 CFR 8874 - Proclamation 8874 of October 1, 2012. National Breast Cancer Awareness Month, 2012

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Breast Cancer Awareness Month, 2012 8874 Proclamation 8874 Presidential Documents Proclamations Proclamation 8874 of October 1, 2012 Proc. 8874 National Breast Cancer Awareness Month, 2012By the President of the United States of America A Proclamation Breast cancer touches the lives of Americans from every...

  18. 3 CFR 8936 - Proclamation 8936 of February 28, 2013. Read Across America Day, 2013

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... America Day, 2013 8936 Proclamation 8936 Presidential Documents Proclamations Proclamation 8936 of February 28, 2013 Proc. 8936 Read Across America Day, 2013By the President of the United States of America A Proclamation Today, people of all ages will mark Read Across America Day by celebrating stories...

  19. 3 CFR 8480 - Proclamation 8480 of March 1, 2010. Read Across America Day, 2010

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... America Day, 2010 8480 Proclamation 8480 Presidential Documents Proclamations Proclamation 8480 of March 1, 2010 Proc. 8480 Read Across America Day, 2010By the President of the United States of America A... require comprehension of the written word. On Read Across America Day, we reaffirm our commitment to...

  20. Imaging of Stellar Surfaces with the Navy Precision Optical Interferometer

    DTIC Science & Technology

    2015-09-18

    geostationary satel- lite with the Navy Prototype Optical Interferome- ter,” in Proc. Optical and Infrared Interferometry II, W. C. Danchi, F...Cormier, “Imag- ing of geostationary satellites with the MRO inter- ferometer,” in Proc. Advanced Maui Optical and Space Surveillance Technologies... geostationary satellites: Signal-to-noise considerations,” in Proc. Advanced Maui Optical and Space Surveillance Technologies Conference, 2011. 6. D

  1. A white noise approach to the Feynman integrand for electrons in random media

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Grothaus, M., E-mail: grothaus@mathematik.uni-kl.de; Riemann, F., E-mail: riemann@mathematik.uni-kl.de; Suryawan, H. P., E-mail: suryawan@mathematik.uni-kl.de

    2014-01-15

    Using the Feynman path integral representation of quantum mechanics it is possible to derive a model of an electron in a random system containing dense and weakly coupled scatterers [see F. Edwards and Y. B. Gulyaev, “The density of states of a highly impure semiconductor,” Proc. Phys. Soc. 83, 495–496 (1964)]. The main goal of this paper is to give a mathematically rigorous realization of the corresponding Feynman integrand in dimension one based on the theory of white noise analysis. We refine and apply a Wick formula for the product of a square-integrable function with Donsker's delta functions and usemore » a method of complex scaling. As an essential part of the proof we also establish the existence of the exponential of the self-intersection local times of a one-dimensional Brownian bridge. As a result we obtain a neat formula for the propagator with identical start and end point. Thus, we obtain a well-defined mathematical object which is used to calculate the density of states [see, e.g., F. Edwards and Y. B. Gulyaev, “The density of states of a highly impure semiconductor,” Proc. Phys. Soc. 83, 495–496 (1964)].« less

  2. 3 CFR 8978 - Proclamation 8978 of May 10, 2013. National Women's Health Week, 2013

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... conditions like pregnancy or cancer. Already, 47 million women have gained access to preventive services at... 3 The President 1 2014-01-01 2014-01-01 false Proclamation 8978 of May 10, 2013. National Women's..., 2013 Proc. 8978 National Women's Health Week, 2013By the President of the United States of America A...

  3. 3 CFR 8699 - Proclamation 8699 of August 25, 2011. Women’s Equality Day, 2011

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... the achievements of women and recommit ourselves to the goal of gender equality in this country. IN... 25, 2011 Proc. 8699 Women’s Equality Day, 2011By the President of the United States of America A... that women-owned businesses can compete in the marketplace, that women are not discriminated against in...

  4. 3 CFR 8623 - Proclamation 8623 of January 14, 2011. Religious Freedom Day, 2011

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 3 The President 1 2012-01-01 2012-01-01 false Proclamation 8623 of January 14, 2011. Religious... 14, 2011 Proc. 8623 Religious Freedom Day, 2011By the President of the United States of America A... Religious Freedom Day, we commemorate Virginia’s 1786 Statute for Religious Freedom, in which Thomas...

  5. 3 CFR 8474 - Proclamation 8474 of January 15, 2010. Religious Freedom Day, 2010

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 3 The President 1 2011-01-01 2011-01-01 false Proclamation 8474 of January 15, 2010. Religious... 15, 2010 Proc. 8474 Religious Freedom Day, 2010By the President of the United States of America A... religious persecution on other continents. Recognizing their strife and toil, it was the genius of America’s...

  6. 3 CFR 8735 - Proclamation 8735 of October 7, 2011. Columbus Day, 2011

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Proc. 8735 Columbus Day, 2011By the President of the United States of America A Proclamation On October... generations reach new horizons. Ten weeks before his arrival in the Americas, Columbus and his crewmembers set... that continue to enrich the fabric of American life. Columbus returned to the Americas three more times...

  7. 3 CFR 9037 - Proclamation 9037 of October 8, 2013. Leif Erikson Day, 2013

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ..., 2013 Proc. 9037 Leif Erikson Day, 2013By the President of the United States of America A Proclamation...'s familiar shores and set sail for Greenland. Erikson and his crew were not aiming to make history... them the first Europeans known to visit North America. Their settlement, Vinland, sustained them in the...

  8. 3 CFR 8488 - Proclamation 8488 of March 31, 2010. Census Day, 2010

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Proc. 8488 Census Day, 2010By the President of the United States of America A Proclamation Since our... census will assess a Nation of over 300 million. America's diversity defines our national character, yet... that all Americans get the support they deserve and a voice in our democracy. NOW, THEREFORE, I, BARACK...

  9. 3 CFR 8354 - Proclamation 8354 of April 1, 2009. National Cancer Control Month, 2009

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 3 The President 1 2010-01-01 2010-01-01 false Proclamation 8354 of April 1, 2009. National Cancer... 1, 2009 Proc. 8354 National Cancer Control Month, 2009By the President of the United States of America A Proclamation We have achieved remarkable progress in the fight against cancer. Miracles in...

  10. 3 CFR 8647 - Proclamation 8647 of April 1, 2011. World Autism Awareness Day, 2011

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 3 The President 1 2012-01-01 2012-01-01 false Proclamation 8647 of April 1, 2011. World Autism..., 2011 Proc. 8647 World Autism Awareness Day, 2011By the President of the United States of America A Proclamation With autism spectrum disorders (ASDs) affecting nearly one percent of children in the United...

  11. 3 CFR 8795 - Proclamation 8795 of April 2, 2012. World Autism Awareness Day, 2012

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 3 The President 1 2013-01-01 2013-01-01 false Proclamation 8795 of April 2, 2012. World Autism..., 2012 Proc. 8795 World Autism Awareness Day, 2012By the President of the United States of America A Proclamation Autism spectrum disorders (ASDs) affect young people and adults of every background, and millions...

  12. 3 CFR 9041 - Proclamation 9041 of October 11, 2013. Columbus Day, 2013

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 3 The President 1 2014-01-01 2014-01-01 false Proclamation 9041 of October 11, 2013. Columbus Day... Proc. 9041 Columbus Day, 2013By the President of the United States of America A Proclamation Late in.... Instead, more than two months later, his crew spotted the Bahamas, and our world was changed forever. A...

  13. 3 CFR 8709 - Proclamation 8709 of September 9, 2011. National Grandparents Day, 2011

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... September 9, 2011 Proc. 8709 National Grandparents Day, 2011By the President of the United States of America A Proclamation The support of loved ones provides the earliest and often most powerful influence on... our grandparents as they have for us. We must keep Social Security strong and viable, while preserving...

  14. 3 CFR 8729 - Proclamation 8729 of October 3, 2011. Child Health Day, 2011

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... making important repairs to schools, like removing asbestos and updating technology. On Child Health Day... 3 The President 1 2012-01-01 2012-01-01 false Proclamation 8729 of October 3, 2011. Child Health..., 2011 Proc. 8729 Child Health Day, 2011By the President of the United States of America A Proclamation...

  15. 3 CFR 8339 - Proclamation 8339 of January 15, 2009. National Sanctity of Human Life Day, 2009

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Sanctity of Human Life Day, 2009 8339 Proclamation 8339 Presidential Documents Proclamations Proclamation 8339 of January 15, 2009 Proc. 8339 National Sanctity of Human Life Day, 2009By the President of the United States of America A Proclamation All human life is a gift from our Creator that is sacred, unique...

  16. 3 CFR 8348 - Proclamation 8348 of February 27, 2009. Save Your Vision Week, 2009

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Vision Week, 2009 8348 Proclamation 8348 Presidential Documents Proclamations Proclamation 8348 of February 27, 2009 Proc. 8348 Save Your Vision Week, 2009By the President of the United States of America A... are critical to minimize vision loss from eye diseases as well as vision loss that is correctable with...

  17. 3 CFR 8961 - Proclamation 8961 of April 19, 2013. National Park Week, 2013

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 3 The President 1 2014-01-01 2014-01-01 false Proclamation 8961 of April 19, 2013. National Park..., 2013 Proc. 8961 National Park Week, 2013By the President of the United States of America A Proclamation... experience it firsthand. This week, the National Park Service will make that opportunity available to...

  18. 3 CFR 8498 - Proclamation 8498 of April 16, 2010. National Park Week, 2010

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 3 The President 1 2011-01-01 2011-01-01 false Proclamation 8498 of April 16, 2010. National Park..., 2010 Proc. 8498 National Park Week, 2010By the President of the United States of America A Proclamation.... During National Park Week, we celebrate the diversity, beauty, and history found in our National Park...

  19. 3 CFR 8362 - Proclamation 8362 of April 17, 2009. National Park Week, 2009

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 3 The President 1 2010-01-01 2010-01-01 false Proclamation 8362 of April 17, 2009. National Park..., 2009 Proc. 8362 National Park Week, 2009By the President of the United States of America A Proclamation America’s National Parks are among our Nation’s most precious treasures. During National Park Week, we...

  20. 3 CFR 8797 - Proclamation 8797 of April 9, 2012. National Volunteer Week, 2012

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 9, 2012 Proc. 8797 National Volunteer Week, 2012By the President of the United States of America A... achieving our highest ambitions—from a world-class education for every child to an economy built to last. During National Volunteer Week, we pay tribute to all who give of themselves to keep America strong, and...

  1. 3 CFR 8974 - Proclamation 8974 of May 1, 2013. National Day of Prayer, 2013

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Prayer, 2013 8974 Proclamation 8974 Presidential Documents Proclamations Proclamation 8974 of May 1, 2013 Proc. 8974 National Day of Prayer, 2013By the President of the United States of America A Proclamation Americans have long turned to prayer both in times of joy and times of sorrow. On their voyage to the New...

  2. 3 CFR 8845 - Proclamation 8845 of July 27, 2012. World Hepatitis Day, 2012

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 3 The President 1 2013-01-01 2013-01-01 false Proclamation 8845 of July 27, 2012. World Hepatitis..., 2012 Proc. 8845 World Hepatitis Day, 2012By the President of the United States of America A Proclamation Worldwide, one in twelve people is living with viral hepatitis—a disease that threatens the health...

  3. 3 CFR 8455 - Proclamation 8455 of November 20, 2009. National Farm-City Week, 2009

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Farm-City Week, 2009 8455 Proclamation 8455 Presidential Documents Proclamations Proclamation 8455 of November 20, 2009 Proc. 8455 National Farm-City Week, 2009By the President of the United States of America... communities are critical to our economy and to the nourishment of our people. During National Farm-City Week...

  4. 3 CFR 8872 - Proclamation 8872 of September 28, 2012. Gold Star Mother's and Family's Day, 2012

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Mother's and Family's Day, 2012 8872 Proclamation 8872 Presidential Documents Proclamations Proclamation 8872 of September 28, 2012 Proc. 8872 Gold Star Mother's and Family's Day, 2012By the President of the United States of America A Proclamation From the revolution that gave life to our Republic to the trials...

  5. 3 CFR 8743 - Proclamation 8743 of November 1, 2011. Military Family Month, 2011

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... make America’s military the finest in the world, their family members embody the resilience and... November 1, 2011 Proc. 8743 Military Family Month, 2011By the President of the United States of America A... 3 The President 1 2012-01-01 2012-01-01 false Proclamation 8743 of November 1, 2011. Military...

  6. 3 CFR 8785 - Proclamation 8785 of March 19, 2012. National Day of Honor

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Proc. 8785 National Day of HonorBy the President of the United States of America A Proclamation Nine... began one of the most challenging missions our military has ever known. They left the comforts of home... Nation’s longest wars, veterans of Operation Iraqi Freedom and Operation New Dawn wrote one of the most...

  7. 3 CFR 8816 - Proclamation 8816 of May 11, 2012. Military Spouse Appreciation Day, 2012

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... ways to give back to our country day after day. The strength and readiness of America’s military..., 2012 Proc. 8816 Military Spouse Appreciation Day, 2012By the President of the United States of America.... Alongside these selfless heroes, our Nation’s military spouses also offer tremendous service and make great...

  8. 3 CFR 8690 - Proclamation 8690 of June 17, 2011. Father's Day, 2011

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Proc. 8690 Father's Day, 2011By the President of the United States of America A Proclamation Parenthood... 3 The President 1 2012-01-01 2012-01-01 false Proclamation 8690 of June 17, 2011. Father's Day... everything they have to build a better future for their family, asking nothing in return but their children’s...

  9. 3 CFR 8756 - Proclamation 8756 of November 18, 2011. National Family Week, 2011

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... November 18, 2011 Proc. 8756 National Family Week, 2011By the President of the United States of America A.... My Administration remains steadfast in our commitment to families across America. To ensure our... loved ones. Our troops and military families serve with valor at home and overseas, and as a Nation we...

  10. 3 CFR 8346 - Proclamation 8346 of February 27, 2009. American Red Cross Month, 2009

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... February 27, 2009 Proc. 8346 American Red Cross Month, 2009By the President of the United States of America..., and the volunteers who respond to them. These efforts include supporting our military and their... helping military families stay connected with service members around the world, teaching CPR and first aid...

  11. 3 CFR 8906 - Proclamation 8906 of November 16, 2012. National Family Week, 2012

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... earned. America’s prosperity has always come from an economy that is built on a strong and growing middle... recommit to keeping America's promise alive for every family. NOW, THEREFORE, I, BARACK OBAMA, President of... November 16, 2012 Proc. 8906 National Family Week, 2012By the President of the United States of America A...

  12. 3 CFR 8598 - Proclamation 8598 of November 5, 2010. Veterans Day, 2010

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Proc. 8598 Veterans Day, 2010By the President of the United States of America A Proclamation On... not our weapons or our technology that make us the most advanced military in the world; it is the... stretching across more than two centuries, our veterans have charged into harm’s way, sometimes making the...

  13. 3 CFR 8768 - Proclamation 8768 of December 28, 2011. National Mentoring Month, 2012

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... December 28, 2011 Proc. 8768 National Mentoring Month, 2012By the President of the United States of America... essential role in preparing our Nation’s youth for a bright future. During National Mentoring Month, we... relative, or a trusted friend, a mentor’s steady and dependable support can inspire a child to strive for...

  14. 3 CFR 8895 - Proclamation 8895 of November 1, 2012. Military Family Month, 2012

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... November 1, 2012 Proc. 8895 Military Family Month, 2012By the President of the United States of America A Proclamation Since our Nation's earliest days, courageous men and women of all backgrounds and beliefs have... 3 The President 1 2013-01-01 2013-01-01 false Proclamation 8895 of November 1, 2012. Military...

  15. 3 CFR 8696 - Proclamation 8696 of July 27, 2011. World Hepatitis Day, 2011

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 3 The President 1 2012-01-01 2012-01-01 false Proclamation 8696 of July 27, 2011. World Hepatitis..., 2011 Proc. 8696 World Hepatitis Day, 2011By the President of the United States of America A..., stem the tide of new infections, and ensure treatment reaches those who need it. On World Hepatitis Day...

  16. 3 CFR 8538 - Proclamation 8538 of June 18, 2010. World Refugee Day, 2010

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 3 The President 1 2011-01-01 2011-01-01 false Proclamation 8538 of June 18, 2010. World Refugee..., 2010 Proc. 8538 World Refugee Day, 2010By the President of the United States of America A Proclamation On World Refugee Day, we honor the contributions and resilience of those forced to flee from their...

  17. 3 CFR 8948 - Proclamation 8948 of March 29, 2013. National Cancer Control Month, 2013

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 3 The President 1 2014-01-01 2014-01-01 false Proclamation 8948 of March 29, 2013. National Cancer... 29, 2013 Proc. 8948 National Cancer Control Month, 2013By the President of the United States of America A Proclamation For more than a decade, Americans have watched the overall cancer death rate drop...

  18. 3 CFR 8644 - Proclamation 8644 of March 31, 2011. National Cancer Control Month, 2011

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 3 The President 1 2012-01-01 2012-01-01 false Proclamation 8644 of March 31, 2011. National Cancer... 31, 2011 Proc. 8644 National Cancer Control Month, 2011By the President of the United States of... fight against cancer. Improvements in early detection and treatment of this disease have led to...

  19. 3 CFR 8673 - Proclamation 8673 of May 12, 2011. Small Business Week, 2011

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 3 The President 1 2012-01-01 2012-01-01 false Proclamation 8673 of May 12, 2011. Small Business..., 2011 Proc. 8673 Small Business Week, 2011By the President of the United States of America A... Street to the high-tech startups that keep America on the cutting edge, small businesses are the backbone...

  20. 3 CFR 8781 - Proclamation 8781 of March 2, 2012. Read Across America Day, 2012

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... America Day, 2012 8781 Proclamation 8781 Presidential Documents Proclamations Proclamation 8781 of March 2, 2012 Proc. 8781 Read Across America Day, 2012By the President of the United States of America A... vital investment not only in their future, but also in an America that leads the world in educating its...

  1. Databases in Healthcare.

    DTIC Science & Technology

    1980-03-01

    34; Proc. ACM Pacific 75 Conference, Boole and Babbage , Palo Alto, CA., 1975. Giebin75 Giebink, G.A., et al: "Current Status of Ambulatory Health Care...13, pp. 36-49, 1978. Stimso78 Stimson, D.H. and G. Charles : "A Computer-Based Information System in an Ambulatory Care System and Case Study" Proc...Base Management Systems" Proc. ACM Pacific 75 Conference, Boole and Babbage , Palo Alto, CA, 1975. Szolov78 Szolovits, P. and S.G. Pauker: "Categorical

  2. A gravitational potential finding for rotating cosmological body in the context of proto-planetary dynamics problem solving

    NASA Astrophysics Data System (ADS)

    Krot, Alexander M.

    2008-09-01

    The statistical theory for a cosmological body forming (so-called the spheroidal body model) has been proposed in [1]-[9]. Within the framework of this theory, bodies have fuzzy outlines and are represented by means of spheroidal forms [1],[2]. In the work [3], it has been investigated a slowly evolving in time process of a gravitational compression of a spheroidal body close to an unstable equilibrium state. In the papers [4],[5], the equation of motion of particles inside the weakly gravitating spheroidal body modeled by means of an ideal liquid has been obtained. Using Schwarzschild's and Kerr's metrics a consistency of the proposed statistical model with the general relativity has been shown in [6]. The proposed theory follows from the conception for forming a spheroidal body from protoplanetary nebula [7],[8]; it permits to derive the form of distribution functions for an immovable [1]-[5] and rotating spheroidal body [6]-[8] as well as their density masses and also the distribution function of specific angular momentum of the rotating uniformly spheroidal body [7],[8]. It is well-known there is not a statistical equilibrium in a gas-dust proto-planetary cloud because of long relaxation time for proto-planets formation in own gravitational field. This proto-planetary system behavior can be described by Jeans' equation in partial derivations relative to a distribution function [9]. The problem for finding a general solution of Jeans' equation is connected directly with an analytical expression for potential of gravitational field. Thus, the determination of gravitational potential is the main problem of statistical dynamics for proto-planetary system [9]. This work shows this task of proto-planetary dynamics can be solved on the basis of spheroidal bodies theory. The proposed theory permits to derive the form of gravitational potential for a rotating spheroidal body at a long distance from its center. Using the obtained analytical expression for potential of gravitational field, the gravitational strength (as well as angular momentum space function) in a remote zone of a slowly gravitational compressed rotating spheroidal body is obtained. As a result, a distribution function describing mechanical state of proto-planetary system can be found from the Jeans' equation. References: [1] Krot AM. The statistical model of gravitational interaction of particles. Uspekhi Sovremennoï Radioelektroniki (special issue "Cosmic Radiophysics", Moscow) 1996; 8: 66-81 (in Russian). [2] Krot AM. Use of the statistical model of gravity for analysis of nonhomogeneity in earth surface. Proc. SPIE's 13th Annual Intern. Symposium "AeroSense", Orlando, Florida, USA, April 5-9, 1999; 3710: 1248-1259. [3] Krot AM. Statistical description of gravitational field: a new approach. Proc. SPIE's 14th Annual Intern.Symposium "AeroSense", Orlando, Florida, USA, April 24-28, 2000; 4038: 1318-1329. [4] Krot AM. Gravidynamical equations for a weakly gravitating spheroidal body. Proc. SPIE's 15th Annual Intern. Symposium "AeroSense", Orlando, Florida, USA, April 16-20, 2001; 4394: 1271-1282. [5] Krot AM. Development of gravidynamical equations for a weakly gravitating body in the vicinity of absolute zero temperature. Proc. 53rd Intern. Astronautical Congress (IAC) - The 2nd World Space Congress-2002, Houston, Texas, USA, October 10-19, 2002; Preprint IAC-02-J.P.01: 1-11. [6] Krot AM. The statistical model of rotating and gravitating spheroidal body with the point of view of general relativity. Proc. 35th COSPAR Scientific Assembly, Paris, France, July 18-25, 2004; Abstract-Nr. COSPAR 04-A- 00162. [7] Krot A. The statistical approach to exploring formation of Solar system. Proc. European Geoscinces Union (EGU) General Assembly, Vienna, Austria, April 02-07, 2006; Geophysical Research Abstracts, vol. 8: EGU06-A- 00216, SRef-ID: 1607-7962/gra/. [8] Krot AM. The statistical model of original and evolution planets of Solar system and planetary satellities. Proc. European Planetary Science Congress, Berlin, Germany, September 18-22, 2006; Planetary Research Abstracts, ESPC2006-A-00014. [9] Krot A. On the principal difficulties and ways to their solution in the theory of gravitational condensation of infinitely distributed dust substance. Proc. XXIV IUGG General Assembly, Perugia, Italy, July 2-13, 2007; GS002 Symposium "Gravity Field", Abstract GS002-3598: 143-144.

  3. Department of Defense Congressional Action on FY 1984 Authorization Request.

    DTIC Science & Technology

    1983-10-11

    AUTHORIZATION NOTE: The Military Construction Bill authorization recommendation totaIS dIO not include projects authorized using savings or authorized for...change from the request). &DE9rooi)00 ti M S in Million (Zallocki- Proc. of Ammunition. Armsy Nerve gas artillery shells .185 Bethune) Proc. of...Ammunitioin. Army Nerve gas production -96S (Gore) Missile Proc, Air Force MX Production funds -357 8 (Byron) ROTE, Air Force T-46A Trainer Aircraft . 200

  4. Unobserved time effects confound the identification of climate change impacts.

    PubMed

    Auffhammer, Maximilian; Vincent, Jeffrey R

    2012-07-24

    A recent study by Feng et al. [Feng S, Krueger A, Oppenheimer M (2010) Proc Natl Acad Sci USA 107:14257-14262] in PNAS reported statistical evidence of a weather-driven causal effect of crop yields on human migration from Mexico to the United States. We show that this conclusion is based on a different statistical model than the one stated in the paper. When we correct for this mistake, there is no evidence of a causal link.

  5. 3 CFR 102.171-102.999 - [Reserved

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Childhood Obesity Awareness Month, 2011 55207 8703 Sept. 1 National Ovarian Cancer Awareness Month, 2011...)Child Health Day (Proc. 8729)Childhood Cancer Awareness Month, National (Proc. 8705)Childhood Obesity...

  6. 3 CFR 8642 - Proclamation 8642 of March 31, 2011. National Donate Life Month, 2011

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 3 The President 1 2012-01-01 2012-01-01 false Proclamation 8642 of March 31, 2011. National Donate... 31, 2011 Proc. 8642 National Donate Life Month, 2011By the President of the United States of America... difference in many lives. As we observe National Donate Life Month, we reflect on an important opportunity to...

  7. 3 CFR 8880 - Proclamation 8880 of October 1, 2012. Child Health Day, 2012

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 3 The President 1 2013-01-01 2013-01-01 false Proclamation 8880 of October 1, 2012. Child Health..., 2012 Proc. 8880 Child Health Day, 2012By the President of the United States of America A Proclamation As a Nation, we share an obligation to ensure the health and well-being of our children. The youth of...

  8. 3 CFR 8954 - Proclamation 8954 of April 1, 2013. World Autism Awareness Day, 2013

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 3 The President 1 2014-01-01 2014-01-01 false Proclamation 8954 of April 1, 2013. World Autism..., 2013 Proc. 8954 World Autism Awareness Day, 2013By the President of the United States of America A... the autism spectrum. It is a reality that affects millions of families every day, from the classroom...

  9. 3 CFR 8786 - Proclamation 8786 of March 23, 2012. Cesar Chavez Day, 2012

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... World War II. And this month, we honor ten Americans as Champions of Change for their commitment to... 3 The President 1 2013-01-01 2013-01-01 false Proclamation 8786 of March 23, 2012. Cesar Chavez..., 2012 Proc. 8786 Cesar Chavez Day, 2012By the President of the United States of America A Proclamation...

  10. 3 CFR 8933 - Proclamation 8933 of February 28, 2013. American Red Cross Month, 2013

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 3 The President 1 2014-01-01 2014-01-01 false Proclamation 8933 of February 28, 2013. American Red... February 28, 2013 Proc. 8933 American Red Cross Month, 2013By the President of the United States of America... communities around the world, and we renew the compassionate spirit that continues to keep our country strong...

  11. Proceedings of the Annual Conference on Manual Control (15th) held March 20 - 22, 1979, Wright State University, Dayton, Ohio

    DTIC Science & Technology

    1979-11-01

    Performance in a Precognitive Tracking Task," Proc. 13th Annual Conf. on Manual Control, pp. 152-165, June 1977. (32] Repa Brian S. and Robert S. Zucker...operators that have received attention in manual control. Precognitive manual control displays differ from the pursuit and compensatory displays of the

  12. 3 CFR 8489 - Proclamation 8489 of April 1, 2010. National Cancer Control Month, 2010

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 3 The President 1 2011-01-01 2011-01-01 false Proclamation 8489 of April 1, 2010. National Cancer... 1, 2010 Proc. 8489 National Cancer Control Month, 2010By the President of the United States of America A Proclamation Cancer is among the leading causes of death in our country, taking over half a...

  13. 3 CFR 8638 - Proclamation 8638 of March 18, 2011. National Poison Prevention Week, 2011

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 3 The President 1 2012-01-01 2012-01-01 false Proclamation 8638 of March 18, 2011. National Poison Prevention Week, 2011 8638 Proclamation 8638 Presidential Documents Proclamations Proclamation 8638 of March 18, 2011 Proc. 8638 National Poison Prevention Week, 2011By the President of the United States of America A Proclamation Each day, emergenc...

  14. 3 CFR 8483 - Proclamation 8483 of March 5, 2010. Save Your Vision Week, 2010

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 3 The President 1 2011-01-01 2011-01-01 false Proclamation 8483 of March 5, 2010. Save Your Vision..., 2010 Proc. 8483 Save Your Vision Week, 2010By the President of the United States of America A Proclamation While many Americans are fortunate to have healthy eyes, millions are affected by low vision or...

  15. 3 CFR 9014 - Proclamation 9014 of September 6, 2013. National Days of Prayer and Remembrance, 2013

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 3 The President 1 2014-01-01 2014-01-01 false Proclamation 9014 of September 6, 2013. National Days of Prayer and Remembrance, 2013 9014 Proclamation 9014 Presidential Documents Proclamations Proclamation 9014 of September 6, 2013 Proc. 9014 National Days of Prayer and Remembrance, 2013By the President of the United States of America A...

  16. 3 CFR 8998 - Proclamation 8998 of July 19, 2013. Captive Nations Week, 2013

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 3 The President 1 2014-01-01 2014-01-01 false Proclamation 8998 of July 19, 2013. Captive Nations Week, 2013 8998 Proclamation 8998 Presidential Documents Proclamations Proclamation 8998 of July 19, 2013 Proc. 8998 Captive Nations Week, 2013By the President of the United States of America A Proclamation As citizens of the oldest democracy on...

  17. 3 CFR 9001 - Proclamation 9001 of July 25, 2013. World Hepatitis Day, 2013

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 3 The President 1 2014-01-01 2014-01-01 false Proclamation 9001 of July 25, 2013. World Hepatitis..., 2013 Proc. 9001 World Hepatitis Day, 2013By the President of the United States of America A Proclamation Each year, we mark World Hepatitis Day to bring attention to a disease that afflicts one in twelve...

  18. 3 CFR 8428 - Proclamation 8428 of October 1, 2009. National Domestic Violence Awareness Month, 2009

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 3 The President 1 2010-01-01 2010-01-01 false Proclamation 8428 of October 1, 2009. National Domestic Violence Awareness Month, 2009 8428 Proclamation 8428 Presidential Documents Proclamations Proclamation 8428 of October 1, 2009 Proc. 8428 National Domestic Violence Awareness Month, 2009By the President of the United States of America A...

  19. 3 CFR 8683 - Proclamation 8683 of May 27, 2011. Prayer for Peace, Memorial Day, 2011

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ..., answered the call of duty with valor and unwavering devotion. From Gettysburg to Kandahar, America’s sons..., 2011 Proc. 8683 Prayer for Peace, Memorial Day, 2011By the President of the United States of America A... for lasting peace. On this solemn day in which Americans unite in remembrance of our country’s fallen...

  20. 3 CFR 8590 - Proclamation 8590 of October 29, 2010. Military Family Month, 2010

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... October 29, 2010 Proc. 8590 Military Family Month, 2010By the President of the United States of America A... exemplify the highest principles of our Nation. Across America, military families inspire us all with their... us safe and free. As America asks ever more of military families, they have a right to expect more of...

  1. 3 CFR 8848 - Proclamation 8848 of August 24, 2012. Women's Equality Day, 2012

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 24, 2012 Proc. 8848 Women's Equality Day, 2012By the President of the United States of America A... secured the right to vote for America's women. The product of profound struggle and fierce hope, the 19th... 3 The President 1 2013-01-01 2013-01-01 false Proclamation 8848 of August 24, 2012. Women's...

  2. 3 CFR 8444 - Proclamation 8444 of October 30, 2009. Military Family Month, 2009

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... October 30, 2009 Proc. 8444 Military Family Month, 2009By the President of the United States of America A Proclamation No one pays a higher price for our freedom than members of our Nation’s military and their... 3 The President 1 2010-01-01 2010-01-01 false Proclamation 8444 of October 30, 2009. Military...

  3. 3 CFR 9046 - Proclamation 9046 of October 28, 2013. Death of Thomas S. Foley Former Speaker of the House of...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Thomas S. Foley Former Speaker of the House of Representatives 9046 Proclamation 9046 Presidential Documents Proclamations Proclamation 9046 of October 28, 2013 Proc. 9046 Death of Thomas S. Foley Former Speaker of the House of RepresentativesBy the President of the United States of America A Proclamation As...

  4. 3 CFR 102.171-102.999 - [Reserved

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Month, 2012 55091 8852 Aug. 31 National Childhood Obesity Awareness Month, 2012 55093 8853 Aug. 31...)Child Health Day (Proc. 8880)Childhood Cancer Awareness Month, National (Proc. 8851)Childhood Obesity...

  5. 3 CFR 102.171-102.999 - [Reserved

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ..., 2013 54737 9007 Aug. 30 National Childhood Obesity Awareness Month, 2013 54739 9008 Aug. 30 National... Health Day (Proc. 9036)Childhood Cancer Awareness Month, National (Proc. 9006)Childhood Obesity Awareness...

  6. Coilable Crystalline Fiber (CCF) Lasers and their Scalability

    DTIC Science & Technology

    2014-03-01

    Fibers: Double-Clad Design Concept of Tm:YAG-Core Fiber and Mode Simulation. Proc. SPIE 2012, 8237 , 82373M. 8. Beach, R. J.; Mitchell, S. C...Dubinskii, M. True Crystalline Fibers: Double-Clad LMA Design Concept of Tm:YAG-Core Fiber and Mode Simulation. Proc. of SPIE 2012, 8237 , 82373M-1...Tm:YAG-Core Fiber and Mode Simulation. Proc. SPIE 8237 , 82373M, 2012. 8. Beach, R. J.; Mitchell, S. C.; Meissner, H. E.; Meissner, O. R.; Krupke, W

  7. pROC: an open-source package for R and S+ to analyze and compare ROC curves.

    PubMed

    Robin, Xavier; Turck, Natacha; Hainard, Alexandre; Tiberti, Natalia; Lisacek, Frédérique; Sanchez, Jean-Charles; Müller, Markus

    2011-03-17

    Receiver operating characteristic (ROC) curves are useful tools to evaluate classifiers in biomedical and bioinformatics applications. However, conclusions are often reached through inconsistent use or insufficient statistical analysis. To support researchers in their ROC curves analysis we developed pROC, a package for R and S+ that contains a set of tools displaying, analyzing, smoothing and comparing ROC curves in a user-friendly, object-oriented and flexible interface. With data previously imported into the R or S+ environment, the pROC package builds ROC curves and includes functions for computing confidence intervals, statistical tests for comparing total or partial area under the curve or the operating points of different classifiers, and methods for smoothing ROC curves. Intermediary and final results are visualised in user-friendly interfaces. A case study based on published clinical and biomarker data shows how to perform a typical ROC analysis with pROC. pROC is a package for R and S+ specifically dedicated to ROC analysis. It proposes multiple statistical tests to compare ROC curves, and in particular partial areas under the curve, allowing proper ROC interpretation. pROC is available in two versions: in the R programming language or with a graphical user interface in the S+ statistical software. It is accessible at http://expasy.org/tools/pROC/ under the GNU General Public License. It is also distributed through the CRAN and CSAN public repositories, facilitating its installation.

  8. PROC IRT: A SAS Procedure for Item Response Theory

    PubMed Central

    Matlock Cole, Ki; Paek, Insu

    2017-01-01

    This article reviews the procedure for item response theory (PROC IRT) procedure in SAS/STAT 14.1 to conduct item response theory (IRT) analyses of dichotomous and polytomous datasets that are unidimensional or multidimensional. The review provides an overview of available features, including models, estimation procedures, interfacing, input, and output files. A small-scale simulation study evaluates the IRT model parameter recovery of the PROC IRT procedure. The use of the IRT procedure in Statistical Analysis Software (SAS) may be useful for researchers who frequently utilize SAS for analyses, research, and teaching.

  9. 3 CFR 8873 - Proclamation 8873 of October 1, 2012. National Arts and Humanities Month, 2012

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 8873 of October 1, 2012 Proc. 8873 National Arts and Humanities Month, 2012By the President of the United States of America A Proclamation After the bombing of Fort McHenry during the War of 1812, a young... 3 The President 1 2013-01-01 2013-01-01 false Proclamation 8873 of October 1, 2012. National Arts...

  10. 3 CFR 8831 - Proclamation 8831 of May 25, 2012. Prayer for Peace, Memorial Day, 2012

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 3 The President 1 2013-01-01 2013-01-01 false Proclamation 8831 of May 25, 2012. Prayer for Peace..., 2012 Proc. 8831 Prayer for Peace, Memorial Day, 2012By the President of the United States of America A... who have borne conflict’s greatest cost, mourn where the wounds of war are fresh, and pray for a just...

  11. 3 CFR 8968 - Proclamation 8968 of April 30, 2013. National Foster Care Month, 2013

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 30, 2013 Proc. 8968 National Foster Care Month, 2013By the President of the United States of America... healthy and safe. It is a promise we owe to the hundreds of thousands of youth in foster care—boys and... them to get a good education, find a job, and build a better life. To give foster youth the support...

  12. Semiconductor Diamond Technology

    DTIC Science & Technology

    1991-12-31

    temperature technologically permits diamond applica- tion to materials which heretofore could not survive the temperature extremes. Scien- tifically, tle...Institute, Research Triangle Park. NC 27709 [3D. Huang, and KM.ekl I Department of Materials Science and Engineering, Pennsylvania State University...34, edited by g. Messier, J.T. Glass, J.E. Butler, and R. Roy ( Materials Research Society, Pittsburgh, PA, 1991). and Conf. Proc. 179th meeting of’ The

  13. 3 CFR 8722 - Proclamation 8722 of September 23, 2011. Gold Star Mother’s and Family’s Day, 2011

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 8722 of September 23, 2011 Proc. 8722 Gold Star Mother’s and Family’s Day, 2011By the President of the United States of America A Proclamation Since our Nation’s earliest days, the men and women of our Armed Forces have demonstrated the courage and heroism that have come to define America. Across shores, in...

  14. 3 CFR 8796 - Proclamation 8796 of April 3, 2012. Education and Sharing Day, U.S.A., 2012

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 3 The President 1 2013-01-01 2013-01-01 false Proclamation 8796 of April 3, 2012. Education and Sharing Day, U.S.A., 2012 8796 Proclamation 8796 Presidential Documents Proclamations Proclamation 8796 of April 3, 2012 Proc. 8796 Education and Sharing Day, U.S.A., 2012By the President of the United States of...

  15. Dynamic Spectrum Sharing with Limited Network State Information

    DTIC Science & Technology

    2010-11-01

    M. L. Honig,"Two-Cell Downlink Noncoherent Cooperation Without Transmitter Phase Alignment", Proc. Globecom Conf., Miami, FL, Dec. 2010. D. Schmidt, W...restrict the number of active streams even though the maximum multiplexing gain is not achieved. 3 Noncoherent Cooperative Broadcasting...study a noncoherent cooperative transmission scheme with two interfering links, which does not require phase alignment. It is assumed that the

  16. An In Vitro Model for Retinal Laser Damage

    DTIC Science & Technology

    2007-01-01

    Approved for public release, distribution unlimited This paper is part of the following report: TITLE: Conference on Optical Interactions with Tissue...necessarily endorsed by the United States Air Force. Optical Interactions with Tissue and Cells XVIII, edited by Steven L. Jacques, William P. Roach, Proc...used for the 532-nm exposures. Verification of laser wavelength was performed with a spectrometer (Ocean Optics ). Figure 4 provides a schematic

  17. 3 CFR 8351 - Proclamation 8351 of March 3, 2009. Women’s History Month, 2009

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 3 The President 1 2010-01-01 2010-01-01 false Proclamation 8351 of March 3, 2009. Womenâs History..., 2009 Proc. 8351 Women’s History Month, 2009By the President of the United States of America A... during Women’s History Month, we remember and celebrate women from all walks of life who have shaped this...

  18. Probabilistic Reverse dOsimetry Estimating Exposure Distribution (PROcEED)

    EPA Pesticide Factsheets

    PROcEED is a web-based application used to conduct probabilistic reverse dosimetry calculations.The tool is used for estimating a distribution of exposure concentrations likely to have produced biomarker concentrations measured in a population.

  19. KSC-01pp0847

    NASA Image and Video Library

    2001-04-19

    KENNEDY SPACE CENTER, FLA. -- At a launch observation site, State Education Commissioner Charlie Crist (left) talks with astronaut Sam Durrance.  Crist was commemorating the 20th anniversary of Space Shuttle program with his visit to KSC for the launch of Space Shuttle Endeavour on mission STS-100.  He accompanied students from Ronald McNair Magnet School, Cocoa, Fla

  20. An enhanced Planetary Radar Operating Centre (PROC)

    NASA Astrophysics Data System (ADS)

    Catallo, C.

    2010-12-01

    Planetary exploration by means of radar systems, mainly using GPRs is an important role of Italy and numerous scientific international space programs are carried out jointly with ESA and NASA by Italian Space Agency, the scientific community and the industry. Three experiments under Italian leadership ( designed and manufactured by the Italian industry) provided by ASI within a NASA/ESA/ASI joint venture framework are successfully operating: MARSIS on-board MEX, SHARAD on-board MRO and CASSINI Radar on-board Cassini spacecraft: the missions have been further extended . Three dedicated operational centers, namely SHOC, (Sharad Operating Centre), MOC (Marsis Operating Center) and CASSINI PAD are operating from the missions beginning to support all the scientific communities, institutional customers and experiment teams operation Each center is dedicated to a single instrument management and control, data processing and distribution and even if they had been conceived to operate autonomously and independently one from each other, synergies and overlaps have been envisaged leading to the suggestion of a unified center, the Planetary Radar Processing Center (PROC). In order to harmonize operations either from logistics point of view and from HW/SW capabilities point of view PROC is designed and developed for offering improved functionalities to increase capabilities, mainly in terms of data exchange, comparison, interpretation and exploitation. PROC is, therefore, conceived as the Italian support facility to the scientific community for on-going and future Italian planetary exploration programs, such as Europa-Jupiter System Mission (EJSM) The paper describes how the new PROC is designed and developed, to allow SHOC, MOC and CASSINI PAD to operate as before, and to offer improved functionalities to increase capabilities, mainly in terms of data exchange, comparison, interpretation and exploitation aiding scientists to increase their knowledge in the field of surface radar sounding: furthermore the flexibility and the big dimensions of the PROC archives allow easy integration of other missions (e.g. EJSM). A specific PROC Web facility and a dedicated high capacity on line storage allow PROC missions status and scientific results spreading, scientific requests submission, news, studies, technical information, radar data images publication and data retrieving (the latter only on science team members request), according to different permissions assigned both to science team members and generic users

  1. Misbalance in type III collagen formation/degradation as a novel serological biomarker for penetrating (Montreal B3) Crohn's disease.

    PubMed

    van Haaften, W T; Mortensen, J H; Karsdal, M A; Bay-Jensen, A C; Dijkstra, G; Olinga, P

    2017-07-01

    Misbalances in extracellular matrix turnover are key factors in the development of stricturing (Montreal B2) and penetrating (Montreal B3) Crohn's disease. To determine whether serological markers for collagen formation and degradation could serve as biomarkers for complications of Crohn's disease. Serum biomarkers for type I, III, V and VI collagen formation (P1NP, Pro-C3, Pro-C5, Pro-C6) and matrix metalloproteinase mediated degradation (C1M, C3M, C5M and C6M) were measured in a retrospective, single centre cohort of 112 patients with Crohn's disease in the terminal ileum (nonstricturing/nonpenetrating: n=40, stricturing: n=55, penetrating: n=17) and 24 healthy controls. Active inflammation was defined as CRP >5 mg/L. C3M and Pro-C5 levels were higher in penetrating vs nonpenetrating/nonstricturing and stricturing disease (33.6±5 vs 25.8±2.2 [P=.004] and 27.2±2.3 [P=.018] nmol/L C3M, 1262.7±259.4 vs 902.9±109.9 [P=.005] and 953.0±106.4 [P=.015] nmol/L Pro-C5). C1M (71.2±26.1 vs 46.2±6.2 nmol/L [P<.001]), C3M (31.6±3.9 vs 26.1±1.6 nmol/L [P=.002] and Pro-C5 levels (1171.7±171.5 vs 909.6±80.4 nmol/L [P=.002]) were higher in patients with active inflammation vs without active inflammation. Pro-C3/C3M-ratios were best to differentiate between penetrating vs nonstricturing/nonpenetrating and stricturing disease with area under the curves of 0.815±0.109 (P<.001) and 0.746±0.114 (P=.002) respectively. Serological biomarkers show that penetrating Crohn's disease is characterised by increased matrix metalloproteinase-9 degraded type III collagen and formation of type V collagen. Active inflammation in Crohn's disease is characterised by increased formation of type V collagen and increased matrix metalloproteinase mediated breakdown of type I, III collagen. Pro-C3/C3M ratios are superior in differentiating between penetrating Crohn's disease vs inflammatory and stricturing Crohn's disease. © 2017 The Authors. Alimentary Pharmacology and Therapeutics published by John Wiley & Sons Ltd.

  2. The statistical model of origin and evolution planets of Solar system and planetary satellities

    NASA Astrophysics Data System (ADS)

    Krot, A.

    There are the theories for exploring Solar system formation in accord Titius-Bode's low: electromagnetic theories (Birkeland (1912), Alfven (1942)), gravitational theories (Schmidt (1944), Woolfson (1964), Safronov (1969), Dole (1970)), nebular theories (Weizsaecker (1943), Kuiper (1949), Nakano (1970)) [1]-[3]. In spite of great number of work aimed to exploring formation of the Solar system, however, the mentioned theories were not able to explain all phenomena. In this connection the statistical theory for a cosmological body forming (so-called the spheroidal body model) has been proposed in [4]-[11]. Within the framework of this theory, bodies have fuzzy outlines and are represented by means of spheroidal forms. In the work [6], which is a continuation of the papers [4], [5], it has been investigated a slowly evolving in time process of a gravitational compression of a spheroidal body close to an unstable equilibrium state. In the papers [7],[8]the equation of motion of particles inside the weakly gravitating spheroidal body modeled by means of an ideal liquid has been obtained. Using Schwarzschild's and Kerr's metrics a consistency of the proposed statistical model with the general relativity has been shown in [12]. The proposed theory proceeds from the conception for forming a spheroidal body as a protoplanet from planetary nebula; it permits to derive the form of distribution functions for an immovable and rotating spheroidal body [4]-[6],[10]-[13] as well as their density masses (gravitational potentials and strengths) and also to find the distribution function of specific angular momentum of the rotating uniformly spheroidal body [13],[14]. Using the specific angular momentum distribution function this work considers a gas- dust protoplanetary cloud as a rotating and gravitating spheroidal body. Because the specific angular momenta are averaged during conglomeration process the specific angular momenta for a planets of Solar system is found. As a result a new low for Solar system planetary distances is derived (it generalizes the well-known Schmidt low). The new low gives a very good estimation of real planetary distances in Solar system (the relative error of estimation is 0%; absolute error of estimation is 0,5% besides its maximal value is equal to 5% for Earth and Pluto). This low has been applied also to estimation of Jupiter's satellities distances in this work. References: [1] M.M.Nieto, The Tutius-Bode low of planetary distances: its his-tory and theory. Pergamon: Oxford, New York et., 1972. [2] V.S. Safronov, Evolution of Protoplanetary cloud and the formation of the Earth and planets. 1969, Moscow, Nauka, (in Russian); NASA Tech. Transl. F-677, Washington, D.C. 1972. [3] A.V. Vityazev, G.V. Pechrnikova and V.S.Safronov, The Terrestrial planets: origin and early evolution. 1990. Moscow, Nauka (in Russian) [4] A.M.Krot, Achievement in Modern Radioelectronics (Special issue "Cosmic Radiophysics", Moscow), no.8, pp.66-81, 1996 (in Russian). [5] A.M.Krot, Proc. SPIE's 13th Annual Intern.Symp. "AeroSense", vol.3710, pp.1248-1259, Orlando, Florida, USA, April 5-9, 1999. [6] A.M.Krot, Proc. SPIE's 14th Annual Intern.Symp. "AeroSense", vol.4038, pp.1318-1329, Orlando, Florida, USA, April 24-28, 2000. [7] A.M.Krot, Proc. SPIE's 15th Annual Intern. Symposium "AeroSense", vol.4394, pp.1271-1282, Orlando, Florida, USA, April 16-20, 2001. [8] A.M.Krot, Proc. 53rd Intern. Astronautical Congress: The World Space Congress-2002, Houston, Texas, USA, October 10-19, 2002, Preprint IAC-02-J.P.01. - 11 p. [9] A.M.Krot, Proc. 34th Scientific Assembly of the Committee on Space Research (COSPAR)- The 2nd World Space Congress (WSC- 2002), October 10-19, 2002,Houston, Texas, USA. [10] A.M.Krot, Proc. of EGS- AGU-EUG Joint Assembly, Nice, France, April 6-11, 2003, Geophysical Research Abstracts, vol.5, EAE03-À-05568, 2003. [11] A.M. Krot, Proc. of 54 Intern. Astronautical Congress (IAC), September 29-October 3, 2003, Bremen, Germany, Preprint IAC-03-J.1.08. -11p. [12] A.M.Krot , Proc. of 35th COSPAR Scientific Assembly, Paris, France, July 18-25, 2004, Abstract-Nr. COSPAR 04-A-00162. [13] A.Krot, Proc. EGU- 2nd General Assembly, Vienna, Austria, April 24-29, 2005, Geophysical Research Abstracts, vol.7, EGU05-A-04550, 2005; SRef-ID: 1607-7962/gra/. [14] A.Krot Proc. EGU- General Assembly, Vienna, Austria, April 02- 07, 2006, Geophysical Research Abstracts, vol.8, EGU06-A-00216, 2006; SRef-ID: 1607-7962/gra/. 2

  3. Differential conductance and defect states in the heavy-fermion superconductor CeCoIn 5

    DOE PAGES

    John S. Van Dyke; Davis, James C.; Morr, Dirk K.

    2016-01-22

    We demonstrate that the electronic band structure extracted from quasiparticle interference spectroscopy [Nat. Phys. 9, 468 (2013)] and the theoretically computed form of the superconducting gaps [Proc. Natl. Acad. Sci. USA 111, 11663 (2014)] can be used to understand the dI/dV line shape measured in the normal and superconducting state of CeCoIn5 [Nat. Phys. 9, 474 (2013)]. In particular, the dI/dV line shape, and the spatial structure of defect-induced impurity states, reflects the existence of multiple superconducting gaps of d x2–y2 symmetry. As a result, these results strongly support a recently proposed microscopic origin of the unconventional superconducting state.

  4. High Strength Steel Weldment Reliability: Weld Metal Hydrogen Trapping.

    DTIC Science & Technology

    1998-02-01

    Reliability : Weld Metal Hydrogen Trapping submitted to : United States Army Research Office Materials Science Division P.O. Box 12211 Research Triangle...Conf. Proc. of Welding and Related Technologies for the XXIth Century, November 1998, Kiev, Ukraine : "Hydrogen Assisted Cracking in...appendices (see appendix IV). Next TTCP workshop will be held from 6th to 8th October 1998, at CANMET , Ottawa, Ontario, Canada. 20 III. Figures 18

  5. Steady-states for shear flows of a liquid-crystal model: Multiplicity, stability, and hysteresis

    NASA Astrophysics Data System (ADS)

    Dorn, Tim; Liu, Weishi

    In this work, we study shear flows of a fluid layer between two solid blocks via a liquid-crystal type model proposed in [C.H.A. Cheng, L.H. Kellogg, S. Shkoller, D.L. Turcotte, A liquid-crystal model for friction, Proc. Natl. Acad. Sci. USA 21 (2007) 1-5] for an understanding of frictions. A characterization on the existence and multiplicity of steady-states is provided. Stability issue of the steady-states is examined mainly focusing on bifurcations of zero eigenvalues. The stability result suggests that this simple model exhibits hysteresis, and it is supported by a numerical simulation.

  6. 3 CFR 102.171-102.999 - [Reserved

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Aug. 31 National Wilderness Month, 2010 54455 8554 Sept. 1 National Childhood Obesity Awareness Month...: Establishing a Task Force on Childhood Obesity 7197 Feb. 23 Notice: Continuation of the National Emergency... (Proc. 8578)Childhood Cancer Awareness Month, National (Proc. 8556)Childhood Obesity Awareness Month...

  7. Study of application rates of aerosol and pump hair sprays. Final report, July 1986-November 1987

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Boggs, R.R.; Belmont, B.

    Application rates of three hair spray dispensing systems, aerosol, pump, and Exxel packaging were determined through a six-week user panel of approximately 300 people. In addition, photochemically reactive organic compounds (PROC) application rates were determined through chemical analysis of the products. The user panel was stratified on the basis of sex, dispenser (pump/aerosol), and age (adult/teen). Weighted-application rates and weighted PROC application rates are included. A Mann-Whitney evaluation was made to evaluate differences between data sets. Product-usage data for both male and female adult groups support the conclusion that increased use of either pumps or Exxel packaging for hair spraymore » would reduce PROC emissions in California. Data from adult groups also indicate that use of Exxel packaging in place of pumps would not reduce PROC. Consumer preference was also sampled. Adult pump users were not very willing to switch to aerosols, but on the order of half of aerosol users were willing to switch to pumps.« less

  8. Human Infrastructure & Human Activity Detection

    DTIC Science & Technology

    2007-07-01

    Personnel Detection Using Seismic Sensors”, Proc. of SPIE, Vol. 5090, 2003, pp. 162-173. [3] J. M. Cathcart , “Phenomenological investigations into...personnel signatures,” Proc. of the SPIE, Vol. 5796, pp. 428-434, May 2005. [4] B. Mauro & J. M. Cathcart , “Analysis of visible band sensors for

  9. UAS-NAS Live Virtual Constructive Distributed Environment (LVC): LVC Gateway, Gateway Toolbox, Gateway Data Logger (GDL), SaaProc Software Design Description

    NASA Technical Reports Server (NTRS)

    Jovic, Srboljub

    2015-01-01

    This document provides the software design description for the two core software components, the LVC Gateway, the LVC Gateway Toolbox, and two participants, the LVC Gateway Data Logger and the SAA Processor (SaaProc).

  10. POPE: Partial Order Preserving Encoding

    DTIC Science & Technology

    2016-09-09

    Alex X. Liu, Ann L. Wang, and Bezawada Bruhadeshwar. Fast range query processing with strong privacy protection for cloud computing . Proc. VLDB...States government. As such, the Government retains a nonexclusive, royalty-free right to publish or reproduce this article , or to allow others to do so...of these schemes the direc- tory in the persistent client storage depends on the full dataset. Thus 1We abuse notation and use OPE to refer to both

  11. Pursuit, Avoidance, and Cohesion in Flight: Multi-Purpose Control Laws and Neuromorphic VLSI

    DTIC Science & Technology

    2010-10-01

    34 Binaural Spectral Cues for Ultrasonic Localization," Proc. International Symposium on Circuits and Systems, pp. 2110 - 2113, 2008 (DOI:10.1109/ISCAS...T. K. Horiuchi, C. Bansal, and T. M. Massoud (2009), " Binaural Intensity Comparison in the Echolocating Bat Using Synaptic Conductance," Proc

  12. KSC-01pp0848

    NASA Image and Video Library

    2001-04-19

    KENNEDY SPACE CENTER, FLA. -- State Education Commissioner Charlie Crist (left) and astronaut Sam Durrance (center) talk to a child and his mother who are waiting at an observation site to watch the launch of Space Shuttle Endeavour on mission STS-100.  Crist was commemorating the 20th anniversary of Space Shuttle program with his visit to KSC for the launch.  He accompanied students from Ronald McNair Magnet School, Cocoa, Fla

  13. Spirochete motility and morpholgy

    NASA Astrophysics Data System (ADS)

    Charon, Nyles

    2004-03-01

    Spirochetes have a unique structure, and as a result their motility is different from that of other bacteria. These organisms can swim in a highly viscous, gel-like medium, such as that found in connective tissue, that inhibits the motility of most other bacteria. In spirochetes, the organelles for motility, the periplasmic flagella, reside inside the cell within the periplasmic space. A given periplasmic flagellum is attached only at one end of the cell, and depending on the species, may or may not overlap in the center of the cell. The number of periplasmic flagella varies from species to species. These structures have been shown to be directly involved in motility and function by rotating within the periplasmic space (1). The present talk focuses on the spirochete that causes Lyme disease, Borrelia burgdorferi. In many bacterial species, cell shape is usually dictated by the peptidoyglycan layer of the cell wall. In the first part of the talk, results will be presented that the morphology of B. burgdorferi is the result of a complex interaction between the cell cylinder and the internal periplasmic flagella resulting in a cell with a flat-wave morphology. Backward moving, propagating waves enable these bacteria to swim and translate in a given direction. Using targeted mutagenesis, we inactivated the gene encoding the major periplasmic flagellar filament protein FlaB. The resulting flaB mutants not only were non-motile, but were rod-shaped (2). Western blot analysis indicated that flaB was no longer synthesized, and electron microscopy revealed that the mutants were completely deficient in periplasmic flagella. Our results indicate that the periplasmic flagella of B. burgdorferi have a skeletal function. These organelles dynamically interact with the rod-shaped cell cylinder to enable the cell to swim, and to confer in part its flat-wave morphology The latter part of the talk concerns the basis for asymmetrical rotation of the periplasmic flagella of B. burgdorferi during chemotaxis. In translational motility, the bundles of periplasmic flagella rotate in opposite directions. When not translating, they rotate in the same direction, and the cells flex. We present evidence that asymmetrical rotation of the bundles during translation does not depend upon the chemotaxis signal transduction system. The histidine kinase CheA is known to be an essential component in the signaling pathway for bacterial chemotaxis. Mutants of cheA in flagellated bacteria continually rotate their flagella in one direction. B. burgdorferi has two copies of cheA. We reasoned that if chemotaxis were essential for asymmetrical rotation of the flagellar bundles, and if the flagellar motors at both cell ends were identical, inactivation of the two cheA genes should result in cells that constant flex. To test this hypothesis, the signaling pathway was completely blocked by construction of a double cheA mutant. This mutant was completely deficient in chemotaxis. Rather than flexing, it failed to reverse, and it continually translated only in one direction. The results indicate that asymmetrical rotation does not depend upon the chemotaxis system but rather upon differences between the two flagellar bundles. We propose that certain factors within the spirochete localize at flagellar motors at one end of the cell to effect this asymmetry (3). References: 1. Charon, N.W. and S.F. Goldstein. 2002. The genetics of motility and chemotaxis of a fascinating group of bacteria: the spirochetes. Ann. Rev. Genetics. 36: 47-73. 2. Motaleb M.A., L. Corum, J.L Bono, A.F. Elias, P. Rosa, D.S. Samuels, N.W. Charon. 2000. Borrelia burgdorferi periplasmic flagella have both skeletal and motility functions. Proc Natl Acad Sci. 2000 97:10899-10904. 3. Li, C. R. Bakker, M. Motaleb, F. Cabello, M.L. Sartakova, and N.W. Charon. 2002. Asymmetrical flagellar rotation in Borrelia burgdorferi non-chemotaxis mutants. Proc. Natl. Acad. Sci. 99:6169-6174.

  14. Advanced Visual and Instruction Systems for Maintenance Support (AVIS-MS)

    DTIC Science & Technology

    2006-12-01

    Hayashi , "Augmentable Reality: Situated Communication through Physical and Digital Spaces," Proc. 2nd Int’l Symp. Wearable Computers, IEEE CS Press...H. Ohno , "An Optical See-through Display for Mutual Occlusion of Real and Virtual Environments," Proc. Int’l Symp. Augmented Reality 2000 (ISARO0

  15. Predicting Database Requirements for Geographic Information Systems in the Year 2000: Long-Term Design Issues for GRASS

    DTIC Science & Technology

    1992-08-01

    Image Processing. Reading, Massachusetts: Addison-Wesley (1977). Graefe, G., "Parallelizing the Volcano Query Processor," Proc. IEEE COMPCON 90...Approach to a Next Generation of Hypermedia System," Proc. IEEE COMPCON 90 (February 1990), pp 520-527. Jellinghaus, R., " Eiffel Linda: An Object

  16. Performance Evaluation of Multihop Packet Radio Networks by Simulation

    DTIC Science & Technology

    1987-03-01

    Multihop Packet Radio Networks," Proc. IEEE, Vol. 75, No. 1, January 1987. [15] 1. Gitman , "On the Capacity of Slotted ALOHA Networks and Some Design...Networks in the Presence of Noise," Proc. Infocom, Washington D. C., April 1985 [40] H. Frank, I. Gitman and R. Van Slyke, " Packet Radio System

  17. Evaluation of Low-volume Sprayers Used in Asian Citrus Psyllid Control Applications

    DTIC Science & Technology

    2010-06-01

    control, p. 149–157. In: B. Aubert, S. Tontyaporn, and D. Buangsuwon (eds.). Proc. Asia Pacific Intl. Conf. Citriculture, Chiang Mai , Thailand, 4–10...planning and management, p. 77–82. In: B. Aubert, S. Tontyaporn, and D. Buangsuwon (eds.). Proc. Asia Pacific Intl. Conf. Citriculture, Chiang Mai , Thailand

  18. Recent Advances In Radar Polarimetry And Polarimetric SAR Interferometry

    DTIC Science & Technology

    2007-02-01

    Workshop, ESA SERRÍN, Frascati, Italy, January 2003. [69] EUSAR 2000 Procs, VDE Verlag, Offenbach, ISBN: 3-8007-2544-4, Munich, Germany, May 2000. [70...EUSAR 2002 Procs, VDE Verlag, Offenbach, ISBN: 3-8007-2697-1, Cologne, Germany, June 2002. [71] Ferro-Famil, L. and E. Pottier, 2000, "Description of

  19. Detection of Explosives on Surfaces Using UV Raman Spectroscopy: Effect of Substrate Color

    DTIC Science & Technology

    2017-10-01

    Jr, editors. Proc. SPIE 5794; Detection and Remediation Technologies for Mines and Minelike Targets X; 2005; Orlando, FL. Bellingham (WA): Society of...detection of 2,4-DNT in contact with sand particles. In: Harmon RS, Broach JT, Holloway JH Jr, editors. Proc. SPIE 6217; Detection and Remediation

  20. Study of the efficacy of aerosol versus nonaerosol laundry products. Final report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Boggs, R.R.; Belmont, B.

    1987-10-01

    The California Air Resources Board estimates that 6.6 tons of photochemically reactive organic compounds (PROC) are released into the environment in California every day because of the use of aerosol laundry products. The project studied the efficacy, ease of product use, and PROC content for three major brands of pre-wash stain removers in available product forms and for five starch products in their available product forms. Efficacy of pre-wash products was generally found to be limited. They were particularly useful for oil and ball point ink removal. Aerosols were found to be slightly superior. PROC content varied from 16-76% onmore » aerosols; none was found in nonaerosols. Aerosols were found to be slightly easier to use by the laboratory investigator. For starches, on synthetic fabrics Faultless aerosol was found to be superior. For natural fabrics, results were mixed. Efficacy per unit cost was found to be high for bulk starches. PROC content for the two aerosols was 5.8% for Faultless and 8.5% for Niagra. Aerosols were easiest to use and bulk products rather difficult to use.« less

  1. Using SAS PROC CALIS to fit Level-1 error covariance structures of latent growth models.

    PubMed

    Ding, Cherng G; Jane, Ten-Der

    2012-09-01

    In the present article, we demonstrates the use of SAS PROC CALIS to fit various types of Level-1 error covariance structures of latent growth models (LGM). Advantages of the SEM approach, on which PROC CALIS is based, include the capabilities of modeling the change over time for latent constructs, measured by multiple indicators; embedding LGM into a larger latent variable model; incorporating measurement models for latent predictors; and better assessing model fit and the flexibility in specifying error covariance structures. The strength of PROC CALIS is always accompanied with technical coding work, which needs to be specifically addressed. We provide a tutorial on the SAS syntax for modeling the growth of a manifest variable and the growth of a latent construct, focusing the documentation on the specification of Level-1 error covariance structures. Illustrations are conducted with the data generated from two given latent growth models. The coding provided is helpful when the growth model has been well determined and the Level-1 error covariance structure is to be identified.

  2. Adaptive Topological Configuration of an Integrated Circuit/Packet-Switched Computer Network.

    DTIC Science & Technology

    1984-01-01

    Gitman et al. [45] state that there are basically two approaches to the integrated network design problem: (1) solve the link/capacity problem for...1972), 1385-1397. 33. Frank, H., and Gitman , I. Economic analysis of integrated voice and data networks: a case study. Proc. of IEEE 66 , 11 (Nov. 1978...1974), 1074-1079. 45. Gitman , I., Hsieh, W., and Occhiogrosso, B. J. Analysis and design of hybrid switching networks. IEEE Trans. on Comm. Com-29

  3. 76 FR 13449 - Proposed Collection; Comment Request for Revenue Procedure 2009-41 (Rev. Proc. 2002-59 Is...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-11

    ... Classification Elections. DATES: Written comments should be received on or before May 10, 2011 to be assured of... Classification Elections. OMB Number: 1545-1771. Revenue Procedure Number: Revenue Procedure 2009-41. (Rev. Proc... Internal Revenue Code for an eligible entity that requests relief for a late classification election filed...

  4. Development and Analysis of Security Policies in Security Enhanced Android

    DTIC Science & Technology

    2012-12-01

    Privilege - Escalation Attacks on Android ,” Proc. 19th Annual...Services, Bethesda, MD, 2011, pp. 239–252. 98 [43] L. Davi, et al. “ Privilege Escalation Attacks on Android ,” Proc. 13th Int. Conf. on Information...TaintDroid. XManDroid dynamically analyzes applications’ transitive permission usage in order to prevent application-level privilege escalation attacks

  5. Using SAS PROC MCMC for Item Response Theory Models

    ERIC Educational Resources Information Center

    Ames, Allison J.; Samonte, Kelli

    2015-01-01

    Interest in using Bayesian methods for estimating item response theory models has grown at a remarkable rate in recent years. This attentiveness to Bayesian estimation has also inspired a growth in available software such as WinBUGS, R packages, BMIRT, MPLUS, and SAS PROC MCMC. This article intends to provide an accessible overview of Bayesian…

  6. 26 CFR 601.201 - Rulings and determinations letters.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... entire group. See, for example, Rev. Proc. 78-15, 1978-2 C.B. 488, and Rev. Proc. 78-16, 1978-2 C.B. 489... rulings to business, trade, or industrial associations or to other similar groups relating to the application of the tax laws to members of the group. However, rulings may be issued to such groups or...

  7. 26 CFR 601.201 - Rulings and determinations letters.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... entire group. See, for example, Rev. Proc. 78-15, 1978-2 C.B. 488, and Rev. Proc. 78-16, 1978-2 C.B. 489... rulings to business, trade, or industrial associations or to other similar groups relating to the application of the tax laws to members of the group. However, rulings may be issued to such groups or...

  8. 26 CFR 601.201 - Rulings and determinations letters.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... entire group. See, for example, Rev. Proc. 78-15, 1978-2 C.B. 488, and Rev. Proc. 78-16, 1978-2 C.B. 489... rulings to business, trade, or industrial associations or to other similar groups relating to the application of the tax laws to members of the group. However, rulings may be issued to such groups or...

  9. 26 CFR 601.201 - Rulings and determinations letters.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... entire group. See, for example, Rev. Proc. 78-15, 1978-2 C.B. 488, and Rev. Proc. 78-16, 1978-2 C.B. 489... rulings to business, trade, or industrial associations or to other similar groups relating to the application of the tax laws to members of the group. However, rulings may be issued to such groups or...

  10. 26 CFR 601.201 - Rulings and determinations letters.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... entire group. See, for example, Rev. Proc. 78-15, 1978-2 C.B. 488, and Rev. Proc. 78-16, 1978-2 C.B. 489... rulings to business, trade, or industrial associations or to other similar groups relating to the application of the tax laws to members of the group. However, rulings may be issued to such groups or...

  11. Using SAS PROC MCMC for Item Response Theory Models

    PubMed Central

    Samonte, Kelli

    2014-01-01

    Interest in using Bayesian methods for estimating item response theory models has grown at a remarkable rate in recent years. This attentiveness to Bayesian estimation has also inspired a growth in available software such as WinBUGS, R packages, BMIRT, MPLUS, and SAS PROC MCMC. This article intends to provide an accessible overview of Bayesian methods in the context of item response theory to serve as a useful guide for practitioners in estimating and interpreting item response theory (IRT) models. Included is a description of the estimation procedure used by SAS PROC MCMC. Syntax is provided for estimation of both dichotomous and polytomous IRT models, as well as a discussion on how to extend the syntax to accommodate more complex IRT models. PMID:29795834

  12. A two-state hysteresis model from high-dimensional friction

    PubMed Central

    Biswas, Saurabh; Chatterjee, Anindya

    2015-01-01

    In prior work (Biswas & Chatterjee 2014 Proc. R. Soc. A 470, 20130817 (doi:10.1098/rspa.2013.0817)), we developed a six-state hysteresis model from a high-dimensional frictional system. Here, we use a more intuitively appealing frictional system that resembles one studied earlier by Iwan. The basis functions now have simple analytical description. The number of states required decreases further, from six to the theoretical minimum of two. The number of fitted parameters is reduced by an order of magnitude, to just six. An explicit and faster numerical solution method is developed. Parameter fitting to match different specified hysteresis loops is demonstrated. In summary, a new two-state model of hysteresis is presented that is ready for practical implementation. Essential Matlab code is provided. PMID:26587279

  13. Rapid Thermal Processing of 3-5 Compound Semiconductors with Application to the Fabrication of Microwave Devices

    DTIC Science & Technology

    1988-05-01

    LE i GOD~’Q~/ SOLID STATE ELECTRONICS LABORATORY STANFORD ELECTRON ICS LABORATORIES DEPARTMENT OF ELECTRICAL ENGINEERING L STANFORD UNIVERSITY...defects in the growth of subsequent layers. Test structures consisting 325 zEP-H~ PrzC~ LE of multiple layers of GaAs or alternating lay ers of GaAs...QA5) ~erhfellowship. ’J L Ho~ viand ) IF Gibtxn,. itecr Res Soc S% mp Proc 52. 15119t 36 Rapid thermal annealing of Si-implanted GaAs with

  14. Structural Basis for Bc12-Regulated Mitochondrion-Dependent Apoptosis

    DTIC Science & Technology

    2005-04-01

    groups , double-resonance (’H/15N or 1H/ 31P) probes had square r.f. which have a considerably narrower ’IN chemical shift coils wrapped directly around...bilayers, which provides no res- B E H olution [Fig. 5(D)]. The peak near 35 ppm results from the amino groups of the lysine side-chains and the N...tissue-specific and physiological state-specific sub- 21. Huang Q, Petros AM, Virgin HW, Fesik SW, Olejniczak ET. Proc. units of the Na+, K+-ATPase. The

  15. PARTIAL REVISION: ABSORPTION SPECTRUM AND QUANTUM STATES OF THE PRASEODYMIUM ION. I. SINGLE CRYSTALS OF PRASEODYMIUM CHLORIDE

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sayre, E.V.; Sancier, K.M.; Freed, S.

    1958-07-01

    In an analysis of term splitting in the absorption spectrum of 24 samples of praseodymium chloride, Judd (Proc. Roy. Soc. (London) A241, 414(1957)) found all but two of the authors' results to be constant with his. A discussion of reconciliation is presentrd, and the authors point out that the error is due to a mistake in descrimination between electronic transitions and the weak vibrationally coupled lines. (J.R.D.)

  16. Decentralized Stackelberg Strategies for Interconnected Stochastic Dynamic Systems

    DTIC Science & Technology

    1977-10-01

    Solutions" IM, Vol.8, No.6, p.413- 430, 1971. (42) Rhodes, I.B., and Luenberger, D.G., "Differential Games with Imperfect State Information", E Trans...34, Proc. Systems E for Power, ERDA Conf. Henniker, New Hampshire, 1975. [47) Starr, A.W., and Ho, Y.C., "Nonzero-Sum Differential Games ", Jt_., [ Vol.3, p...CONTROLLING OFFICE NAME AND ADDRESS 12. REPORT DATE October, 1977 Joint Services Electronics Program ,3. NUMSEROWPAGES 97 14. MONITORiNG &GENCY NAME 1

  17. KSC-01pp0855

    NASA Image and Video Library

    2001-04-19

    KENNEDY SPACE CENTER, FLA. -- Students from Ronald McNair Magnet School, Cocoa, Fla., gather outside the school bus, posing with their chaperone, teacher Nicole Waxberg (front left, in school t-shirt), astronaut Sam Durrance (center, in uniform) and State Education Commissioner Charlie Crist (right, in white shirt).  All were at KSC to watch the launch of  Space Shuttle Endeavour on mission STS-100.  Crist was commemorating the 20th anniversary of Space Shuttle program with his visit

  18. Condition Monitoring Techniques for Electromechanical Equipment Used in Air Force Ground C3I (Command, Control, Communications and Intelligence) Systems.

    DTIC Science & Technology

    1983-08-01

    Proc. 2nd Congress National de flabilite, Perros -Guirec, Sept. 17-20, 1974, pp. 639-653. Published by CNET, Lannion (France). 53. Love, A. E. H., A...96. C. Rosiaux, Fiabilite des allumeurs determinee a partir des ventes-echanges, Proc. 2nd Congres National de fiabilite, Perros Guirec, Sept. 17-20

  19. Terrestrial Planet Finder Interferometer (TPF-1) Whitepaper for the AAAC Exoplanet Task Force

    DTIC Science & Technology

    2007-04-02

    very strong indication of a biological release ( Lovelock 1980; Sagan et al. 1993). The three strongest bands in the Earth-analog spectrum, O3 band...A., Henry, C. A., et al. 2005, Proc. SPIE, 5905, 8 Lay, O. P. 2006, Proc. SPIE, 6268, 62681A Lovelock , J. E. 1980, Cosmic Search, 2, (4), 2 Martin

  20. Maritime In Situ Sensing Inter-Operable Networks (MISSION)

    DTIC Science & Technology

    2013-09-30

    creating acoustic communications (acomms) technologies enabling underwater sensor networks and distributed systems. Figure 1. Project MISSION...Marn, S. Ramp, F. Bahr, “Implementation of an Underwater Wireless Sensor Network in San Francisco Bay,” Proc. 10th International Mine Warfare...NILUS – An Underwater Acoustic Sensor Network Demonstrator System,” Proc. 10th International Mine Warfare Technology Symposium, Monterey, CA, May 7

  1. Protein Structure Validation and Refinement Using Amide Proton Chemical Shifts Derived from Quantum Mechanics

    PubMed Central

    Christensen, Anders S.; Linnet, Troels E.; Borg, Mikael; Boomsma, Wouter; Lindorff-Larsen, Kresten; Hamelryck, Thomas; Jensen, Jan H.

    2013-01-01

    We present the ProCS method for the rapid and accurate prediction of protein backbone amide proton chemical shifts - sensitive probes of the geometry of key hydrogen bonds that determine protein structure. ProCS is parameterized against quantum mechanical (QM) calculations and reproduces high level QM results obtained for a small protein with an RMSD of 0.25 ppm (r = 0.94). ProCS is interfaced with the PHAISTOS protein simulation program and is used to infer statistical protein ensembles that reflect experimentally measured amide proton chemical shift values. Such chemical shift-based structural refinements, starting from high-resolution X-ray structures of Protein G, ubiquitin, and SMN Tudor Domain, result in average chemical shifts, hydrogen bond geometries, and trans-hydrogen bond (h3 JNC') spin-spin coupling constants that are in excellent agreement with experiment. We show that the structural sensitivity of the QM-based amide proton chemical shift predictions is needed to obtain this agreement. The ProCS method thus offers a powerful new tool for refining the structures of hydrogen bonding networks to high accuracy with many potential applications such as protein flexibility in ligand binding. PMID:24391900

  2. Noise, fluctuation, and HADAMARD-transform spectrometry

    NASA Astrophysics Data System (ADS)

    Nitzsche, Guenter; Riesenberg, Rainer

    2003-05-01

    The HADAMARD principle is known in optics as a multiplex technique. It describes the mode with the most advantageous increase of the signal-to-noise ratio (SNR) in terms of scanning (Fellget advantage). The maximum increase of SNR, we call it gain, is (n+1)/(2On), where n is the number of multiplexing. It is valid in the case of pure detector noise. The multiplex encoding Hadamard pattern in case of n = 7 is 1110100, whereby 1 stands for a switched on channel performed by a field selector. The signals of all (switched on) channels are detected by a single detector. n measurement steps with a cyclic change of the pattern is necessary to perform the Hadamard transformation and to get the result of each individual channel. In case of n = 7 the theoretical gain is 1.51. For all possible multiplex pattern (1100000, 1110000 and so on) the gain is theoretically investigated. A multiplexing advantage (gain > 1) is reached only by the Hadamard pattern, the inverse Hadamard pattern and for (0111111)-pattern (gain=1.08). Most of the multiplex pattern are disadvantageous. The reason for maximum gain of the HADAMARD transformation is analysed theoretically. Signal fluctuations during the measurement caused by fluctuations of the illumination or by the object under test, reduce the multiplex gain, too. So the limits for realizing a gain are estimated theoretically. Essential is the transformation procedure and its influence on the error propagation. The results could be verified by experiments with array spectrometeres. Requirements are derived by numerical simulation concerning the stability of the signals to be multiplexed. It is simulated the needed stability of the signals with increasing order of multiplexing. So the increase of the multiplex gain is limited by signal fluctuations. A realized 96 channel spectral reader is presented as a modern application of an optical multiplexing arrangement. ! M. Harvid, N. J. A. Sloane, Hadamard Transform Optics, Academic Press, 1979 ! R.A. De Verse, R.M. Hammaker, W. G. Fately, J.A.Graham, J.D.Tate, "Spectrometry and imaging using a digital micromirror array" American Laboratory, Vol. 30, 21, pp. 112-120, 1998 ! R. Riesenberg, A. Wuttig, B. Harnisch, "Optical MEMS Technology for Multiplexing in High-End Micro-Scpectrometers", Proc. SPIE 4928, 6-14, 2002 ! A. Wuttig, R. Riesenberg, "Hyperspectral imager with a facile MEMS", Proc. SPIE 4881A, 2002, to be published ! R. Riesenberg, G. Nitzsche, W. Voigt, 'HADAMARD Encoding and other optical Multiplexing', VDI-Berichte 1694, pp. 345-350, 2002 ! A. Wuttig, R. Riesenberg, G. Nitzsche, "Subpixel Analysis of Double Array Grating Spectrometer", Proc. SPIE 4480, pp. 334-344, 2002 ! A. Wuttig, R. Riesenberg, G. Nitzsche, "Integral Field and Multi Object Spectrometry with MEMS", Proc. SPIE 4480, pp. 367-376, 2002 ! R. Riesenberg, G. Nitzsche, A. Wuttig, B. Harnisch, "Micro Spectrometer and MEMS for Space" in "Smaller Satellites: Bigger Business?", edited by M. Rycroft, N. Crosby, Kluwer Academic Publisher, pp. 403-406, 2002 ! R. Riesenberg, A. Wuttig, "Optical sensors with MEMS, slit masks and micromechanical devices", Proc. SPIE 4561, pp. 315-322, 2001 ! R. Riesenberg, "MicroMechanical Slit Positioning System as a transmissive spatial Light Modulator", Proc. SPIE 4457, pp.197-203, 2001 ! R. Riesenberg, J. Lonschinski, "HADAMARD-Minispectrometer made by a Micro Device", Proc. "3rd Round Table on Micro/NanoTechnologies for Space", ESTEC, Noordwijk, The Netherlands, pp. 291 - 297, 2000 ! R. Riesenberg, U. Dillner, "HADAMARD Imaging Spectrometers", Proc. SPIE 3753, pp. 203-213, 1999 ! R. Riesenberg, Th. Seifert, "Design of spatial Light Modulator Microdevices - Micro Slit Arrays", Proc. SPIE 3680, Part One, pp. 406-414, 1999 ! R. Riesenberg, W. Voigt, J. Schoneich, "Compact Spectrometers made by Micro System Technology", Sensor 97, Proc. Vol. 2, pp. 145-150,1997

  3. KSC-04pd0930

    NASA Image and Video Library

    2004-03-31

    KENNEDY SPACE CENTER, FLA. - An aerial photo of the Space Life Sciences Lab at KSC. The new lab is a state-of-the-art facility built for ISS biotechnology research. It was developed as a partnership between NASA KSC and the State of Florida.

  4. KSC-04pd0931

    NASA Image and Video Library

    2004-03-31

    KENNEDY SPACE CENTER, FLA. - An aerial photo of the Space Life Sciences Lab at KSC. The new lab is a state-of-the-art facility built for ISS biotechnology research. It was developed as a partnership between NASA KSC and the State of Florida.

  5. KSC-04pd0932

    NASA Image and Video Library

    2004-03-31

    KENNEDY SPACE CENTER, FLA. - An aerial photo of the Space Life Sciences Lab at KSC. The new lab is a state-of-the-art facility built for ISS biotechnology research. It was developed as a partnership between NASA KSC and the State of Florida.

  6. PTEN Loss Antagonizes Calcitriol-Mediated Growth Inhibition in Prostate Epithelial Cells

    DTIC Science & Technology

    2009-05-01

    deleting lentiviral vector: efficient gene targeting in vivo. Proc Natl Acad Sci U S A, 98: 11450-11455, 2001. 27. Vlahos , C. J., Matter, W. F., Hui, K...and in aging skin in vivo. Proc Natl Acad Sci U S A, 92: 9363-9367, 1995. 35. Vlahos , C. J., Matter, W. F., Hui, K. Y., and Brown, R. F. A specific

  7. Stationary Digital Tomosynthesis System for Early Detection of Breast Tumors

    DTIC Science & Technology

    2011-05-01

    selenium flat panel detector. Proc. SPIE 2005. 5745: p. 529-540 4. Kopans, D.B., Breast Imaging. 2 ed. 1997, New York Lippincott Williams and...same. 2005. 8. M. Bissonnette, et al. Digital breast tomosynthesis using an amorphous selenium flat panel detector. in Medical Imaging 2005...tomosynthesis system with selenium based flat panel detector. Proc of SPIE, Physics of Medical Imaging, 2005. 5745. 12

  8. Research in Stochastic Processes

    DTIC Science & Technology

    1988-08-31

    stationary sequence, Stochastic Proc. Appl. 29, 1988, 155-169 T. Hsing, J. Husler and M.R. Leadbetter, On the exceedance point process for a stationary...Nandagopalan, On exceedance point processes for "regular" sample functions, Proc. Volume, Oberxolfach Conf. on Extreme Value Theory, J. Husler and R. Reiss...exceedance point processes for stationary sequences under mild oscillation restrictions, Apr. 88. Obermotfach Conf. on Extremal Value Theory. Ed. J. HUsler

  9. Thermochemical Processes in Plasma Aerodynamics

    DTIC Science & Technology

    2006-06-01

    hydrocarbon fuel possesses not only much lower induction time but also more effective potential in thermodynamic combustion cycle (more complete exergy ... Internal Plasma- Assisted Combustion, AIAA Paper 2004-1014. Proc. 42 "d AIAA Aerospace Sciences Meeting & Exhibit, 4-8 January 2004, Reno, NV, P. 10 2...Vystavkin N, Sukovatkin N, Serov Yu, Savischenko N, Yuriev A., External and Internal Plasma- Assisted Combustion AIAA Paper 2003-6240. Proc. 41st

  10. The Relativistic Geometry and Dynamics of Electrons

    NASA Astrophysics Data System (ADS)

    Atiyah, M. F.; Malkoun, J.

    2018-02-01

    Atiyah and Sutcliffe (Proc R Soc Lond Ser A 458:1089-1115, 2002) made a number of conjectures about configurations of N distinct points in hyperbolic 3-space, arising from ideas of Berry and Robbins (Proc R Soc Lond Ser A 453:1771-1790, 1997). In this paper we prove all these conjectures, purely geometrically, but we also provide a physical interpretation in terms of Electrons.

  11. KSC-01pp0853

    NASA Image and Video Library

    2001-04-19

    KENNEDY SPACE CENTER, FLA. -- During his visit to KSC for the launch of  Space Shuttle Endeavour on mission STS-100, State Education Commissioner Charlie Crist (right) talks to Jerry Moyer of Dynamac (Bionetics).  At far left is Jay Burmer, FDOE, Director, Central Florida Office. Second from right is astronaut Sam Durrance.  Crist and Durrance accompanied students from Ronald McNair Magnet School, Cocoa, Fla., for the launch.  Crist was commemorating the 20th anniversary of Space Shuttle program with his visit to KSC

  12. KSC-01pp0849

    NASA Image and Video Library

    2001-04-19

    KENNEDY SPACE CENTER, FLA. -- State Education Commissioner Charlie Crist  (background, right) talks to students from Ronald McNair Magnet School, Cocoa, Fla., on the school bus that brought them to KSC for the launch of Space Shuttle Endeavour on mission STS-100. Crist was commemorating the 20th anniversary of Space Shuttle program with his visit to KSC for the launch.  In uniform (center) is astronaut Sam Durrance, who also accompanied the students.  At far left is teacher Nicole Waxberg, who chaperoned the students

  13. Accelerated collagen turnover in women with angina pectoris without obstructive coronary artery disease: An iPOWER substudy.

    PubMed

    Nielsen, Signe H; Mygind, Naja D; Michelsen, Marie M; Bechsgaard, Daria F; Suhrs, Hannah E; Genovese, Federica; Nielsen, Henning B; Brix, Susanne; Karsdal, Morten; Prescott, Eva; Kastrup, Jens

    2018-05-01

    Aim Collagens are major cardiac extracellular matrix components, known to be actively remodelled and accumulated during diffuse myocardial fibrosis. We evaluated whether accelerated collagen turnover described by neo-epitope biomarkers reflecting collagen formation and degradation separates patients with diffuse myocardial fibrosis from asymptomatic controls. Methods and results Seventy-one women with angina pectoris without significant coronary artery disease assessed by invasive coronary angiogram were included. Competitive enzyme-linked immunosorbent assays (ELISAs) measuring circulating protein fragments in serum assessed the formation and degradation of collagen type III (Pro-C3, C3M and C3C), IV (P4NP7S and C4M), V (Pro-C5 and C5M) and VI (Pro-C6 and C6M), and degradation of collagen type I (C1M). Serum samples from 32 age-matched asymptomatic women were included as controls. Symptomatic women presented significantly elevated levels of Pro-C6, C3C, C3M, C4M and C8-C ( p < 0.0001-0.0058) and significantly decreased levels of Pro-C3, C5M and C6M ( p < 0.0001-0.041), reflecting accelerated collagen turnover and an imbalanced collagen formation and degradation compared to controls. Cardiac magnetic resonance T1 mapping was performed to determine extracellular volume fraction and thus diffuse myocardial fibrosis. A significant association was identified between C5M and extracellular volume fraction by cardiac magnetic resonance ( p = 0.01). Conclusion Women with angina pectoris, but without significant obstructive coronary artery disease, showed an imbalanced collagen turnover compared to asymptomatic controls. The examined biomarkers are tools to monitor active collagen remodelling in patients with angina pectoris, in risk of developing myocardial fibrosis.

  14. A possible extension to the RInChI as a means of providing machine readable process data.

    PubMed

    Jacob, Philipp-Maximilian; Lan, Tian; Goodman, Jonathan M; Lapkin, Alexei A

    2017-04-11

    The algorithmic, large-scale use and analysis of reaction databases such as Reaxys is currently hindered by the absence of widely adopted standards for publishing reaction data in machine readable formats. Crucial data such as yields of all products or stoichiometry are frequently not explicitly stated in the published papers and, hence, not reported in the database entry for those reactions, limiting their usefulness for algorithmic analysis. This paper presents a possible extension to the IUPAC RInChI standard via an auxiliary layer, termed ProcAuxInfo, which is a standardised, extensible form in which to report certain key reaction parameters such as declaration of all products and reactants as well as auxiliaries known in the reaction, reaction stoichiometry, amounts of substances used, conversion, yield and operating conditions. The standard is demonstrated via creation of the RInChI including the ProcAuxInfo layer based on three published reactions and demonstrates accurate data recoverability via reverse translation of the created strings. Implementation of this or another method of reporting process data by the publishing community would ensure that databases, such as Reaxys, would be able to abstract crucial data for big data analysis of their contents.

  15. The effect of millisecond flash lamp annealing on electrical and structural properties of ZnO:Al/Si structures

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lindberg, P. F.; Riise, H. N.; Vines, L.

    2016-05-14

    The effect of millisecond flash lamp annealing (FLA) on aluminum doped ZnO (AZO) films and their interface with Si have been studied. The AZO films were deposited by magnetron sputtering on Si (100) substrates. The electrical and structural properties of the film and AZO/Si structures were characterized by current–voltage, capacitance–voltage, and deep level transient spectroscopy measurements, X-ray diffraction, and secondary ion mass spectrometry. The resistivity of the AZO film is reduced to a close to state-of-the-art value of 2 × 10{sup −4} Ω cm after FLA for 3 ms with an average energy density of 29 J/cm{sup 2}. In addition, most of the interfacial defects energymore » levels are simultaneously annealed out, except for one persisting shallow level, tentatively assigned to the vacancy-oxygen complex in Si, which was not affected by FLA. Subsequent to the FLA, the samples were treated in N{sub 2} or forming gas (FG) (N{sub 2}/H{sub 2}, 90/10%{sub mole}) ambient at 200–500 °C. The latter samples maintained the low resistivity achieved after the FLA, but not the former ones. The interfacial defect level persisting after the FLA is removed by the FG treatment, concurrently as another level emerges at ∼0.18 eV below the conduction band. The electrical data of the AZO films are discussed in term of point defects controlling the resistivity, and it is argued that the FLA promotes formation of electrically neutral clusters of Zink vacancies (V{sub Zn}'s) rather than passivating/compensating complexes between the Al donors and V{sub Zn}'s.« less

  16. KSC-04pd0644

    NASA Image and Video Library

    2004-03-26

    KENNEDY SPACE CENTER, FLA. -- An aerial photo of the recently completed Space Life Sciences Lab at KSC. The new lab is a state-of-the-art facility built for ISS biotechnology research. It was developed as a partnership between NASA-KSC and the State of Florida.

  17. KSC-04pd0645

    NASA Image and Video Library

    2004-03-26

    KENNEDY SPACE CENTER, FLA. -- An aerial photo of the recently completed Space Life Sciences Lab at KSC. The new lab is a state-of-the-art facility built for ISS biotechnology research. It was developed as a partnership between NASA-KSC and the State of Florida.

  18. KSC-04pd0646

    NASA Image and Video Library

    2004-03-26

    KENNEDY SPACE CENTER, FLA. -- An aerial photo of the recently completed Space Life Sciences Lab at KSC. The new lab is a state-of-the-art facility built for ISS biotechnology research. It was developed as a partnership between NASA-KSC and the State of Florida.

  19. KSC-04pd0647

    NASA Image and Video Library

    2004-03-26

    KENNEDY SPACE CENTER, FLA. -- An aerial photo of the recently completed Space Life Sciences Lab at KSC. The new lab is a state-of-the-art facility built for ISS biotechnology research. It was developed as a partnership between NASA-KSC and the State of Florida.

  20. KENNEDY SPACE CENTER, FLA. - Workers in KSC's Vertical Processing Facility prepare a solid state recorder for installation in a protective enclosure as part of the prelaunch preparations for STS-82, the second Hubble Space Telescope servicing mission. The digital solid state recorder will replace one of three engineering/science tape recorders on Hubble. The solid state recorder has no moving parts to wear out. It also is more flexible than a reel-to-reel recorder and can store 10 times as much data. Liftoff aboard Discovery is targeted Feb. 11 with a crew of seven.

    NASA Image and Video Library

    1997-01-16

    KENNEDY SPACE CENTER, FLA. - Workers in KSC's Vertical Processing Facility prepare a solid state recorder for installation in a protective enclosure as part of the prelaunch preparations for STS-82, the second Hubble Space Telescope servicing mission. The digital solid state recorder will replace one of three engineering/science tape recorders on Hubble. The solid state recorder has no moving parts to wear out. It also is more flexible than a reel-to-reel recorder and can store 10 times as much data. Liftoff aboard Discovery is targeted Feb. 11 with a crew of seven.

  1. KENNEDY SPACE CENTER, FLA. - Workers in KSC's Vertical Processing Facility install a solid state recorder into a transport assembly in its protective enclosure as part of the prelaunch preparations for STS-82, the second Hubble Space Telescope servicing mission. The digital solid state recorder will replace one of three engineering/science tape recorders on Hubble. The solid state recorder has no moving parts to wear out. It also is more flexible than a reel-to-reel recorder and can store 10 times as much data. Liftoff aboard Discovery is targeted Feb. 11 with a crew of seven.

    NASA Image and Video Library

    1997-01-16

    KENNEDY SPACE CENTER, FLA. - Workers in KSC's Vertical Processing Facility install a solid state recorder into a transport assembly in its protective enclosure as part of the prelaunch preparations for STS-82, the second Hubble Space Telescope servicing mission. The digital solid state recorder will replace one of three engineering/science tape recorders on Hubble. The solid state recorder has no moving parts to wear out. It also is more flexible than a reel-to-reel recorder and can store 10 times as much data. Liftoff aboard Discovery is targeted Feb. 11 with a crew of seven.

  2. KENNEDY SPACE CENTER, FLA. - Valerie Cassanto, with Instrumentation Technology Associates, Inc., and Bob McLean, from the Southwest Texas State University, work on an experiment found during the search for Columbia debris. Included in the Commercial ITA Biomedical Experiments payload on mission STS-107 are urokinase cancer research, microencapsulation of drugs, the Growth of Bacterial Biofilm on Surfaces during Spaceflight (GOBBSS), and tin crystal formation.

    NASA Image and Video Library

    2003-05-06

    KENNEDY SPACE CENTER, FLA. - Valerie Cassanto, with Instrumentation Technology Associates, Inc., and Bob McLean, from the Southwest Texas State University, work on an experiment found during the search for Columbia debris. Included in the Commercial ITA Biomedical Experiments payload on mission STS-107 are urokinase cancer research, microencapsulation of drugs, the Growth of Bacterial Biofilm on Surfaces during Spaceflight (GOBBSS), and tin crystal formation.

  3. An Innovative Multi-Agent Search-and-Rescue Path Planning Approach

    DTIC Science & Technology

    2015-03-09

    search problems from search theory and artificial intelligence /distributed robotic control, and pursuit-evasion problem perspectives may be found in...Dissanayake, “Probabilistic search for a moving target in an indoor environment”, In Proc. IEEE/RSJ Int. Conf. Intelligent Robots and Systems, 2006, pp...3393-3398. [7] H. Lau, and G. Dissanayake, “Optimal search for multiple targets in a built environment”, In Proc. IEEE/RSJ Int. Conf. Intelligent

  4. Securing BGP Using External Security Monitors

    DTIC Science & Technology

    2006-01-01

    forms. In Proc. SOSP, Brighton , UK , Oct. 2005. [19] A. Seshadri, A. Perrig, L. van Doorn, and P. Khosla. SWATT: Software-based Attestation for...Williams, E. G. Sirer, and F. B. Schnei- der. Nexus: A New Operating System for Trustwor- thy Computing (extended abstract). In Proc. SOSP, Brighton , UK ...as a distributed database of untrustworthy hosts or messages. An ESM that detects invalid behavior issues a certifi- cate describing the behavior or

  5. Antithrombin deficiency and decreased protein C activity in a young man with venous thromboembolism: a case report.

    PubMed

    Wang, Dong; Tian, Min; Cui, Guanglin; Wang, Dao Wen

    2018-06-01

    Antithrombin and protein C are two crucial members in the anticoagulant system and play important roles in hemostasis. Mutations in SERPINC1 and PROC lead to deficiency or dysfunction of the two proteins, which could result in venous thromboembolism (VTE). Here, we report a Chinese 22-year-old young man who developed recurrent and serious VTE in cerebral veins, visceral veins, and deep veins of the lower extremity. Laboratory tests and direct sequencing of PROC and SERPINC1 were conducted for the patient and his family members. Coagulation tests revealed that the patient presented type I antithrombin deficiency combined with decreased protein C activity resulting from a small insertion mutation c.848_849insGATGT in SERPINC1 and a short deletion variant c.572_574delAGA in PROC. This combination of the two mutations was absent in 400 healthy subjects each from southern and northern China. Then, we summarized all the mutations of the SERPINC1 and PROC gene reported in the Chinese Han population. This study demonstrates that the combination of antithrombin deficiency and decreased protein C activity can result in severe VTE and that the coexistence of different genetic factors may increase the risk of VTE.

  6. State-of-the-Art for Assessing Earthquake Hazards in the United States. Report 25. Parameters for Specifying Intensity-Related Earthquake Ground Motions.

    DTIC Science & Technology

    1987-09-01

    and Sponheuer, W. 1969. Scale of Seismic Intensity: Proc. Fourth World Conf. on Earthquake Engineering, Santiago, Chile . Murphy, J. R., and O’Brien, L...Predom V/H el, V/I Vel V/H Displ V/H sec VIH Period Period Predom Accel cm/sec Vel cm Disp .05 Dur sec sec Period S11 2 0.48 MODIFIED MERCALLI INTENSITY...0.1 0. 0.16 142.20 Long. Vert Hor Vert Ratio Ratio Vert Ratio Vert r io Du r atio Predom Predom VIH Acce V/H Vel V /H Dspi V H sec 1, H Period Period

  7. Carbon nanoparticle doped micro-patternable nano-composites for wearable sensing applications (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Khosla, Ajit

    2017-04-01

    This talk focuses on preparation, characterization and micropatterning of electrically conducting KETJENBLACK carbon black nanoparticle (80 nm-diameter) doped Polydimethylsiloxane (PDMS) by employing extrusion mixing. Previously, we had reported fabrication of various micropatternable nanocomposites for wearable sensing applications vis solvent assisted ultrasonic mixing technique[1-16] . Extrusion mixing has an advantage as no organic solvents are used and homogenous dispersion of carbon nanoparticles is observed, which is confirmed by SEM analysis. The developed nanocomposite can be micropatterened using standard microfabrication techniques. It is also observed that percolation threshold occurs at 0.51 wt% of carbon nanoparticles in polymer matrix. Examples of developed nano-composites for wearable sensing applications for precision medicine will also be discussed. References: 1.http://summit.sfu.ca/item/12017 A. Khosla. Micropatternable multifunctional nanocomposite polymers for flexible soft MEMS applications. Diss. Applied Science: School of Engineering Science, 2011. 2. A. Khosla ; B. L. Gray; Fabrication of multiwalled carbon nanotube polydimethylsiloxne nanocomposite polymer flexible microelectrodes for microfluidics and MEMS. Proc. SPIE 7642, Electroactive Polymer Actuators and Devices (EAPAD) 2010, 76421V (April 09, 2010); doi:10.1117/12.847292. 3. Ang Li ; Ajit Khosla ; Connie Drewbrook ; Bonnie L. Gray; Fabrication and testing of thermally responsive hydrogel-based actuators using polymer heater elements for flexible microvalves. Proc. SPIE 7929, Microfluidics, BioMEMS, and Medical Microsystems IX, 79290G (February 14, 2011); doi:10.1117/12.873197. 4. Khosla, A. and Gray, B. L. (2010), Preparation, Micro-Patterning and Electrical Characterization of Functionalized Carbon-Nanotube Polydimethylsiloxane Nanocomposite Polymer. Macromol. Symp., 297: 210-218. doi:10.1002/masy.200900165 5. A. Khosla ; D. Hilbich ; C. Drewbrook ; D. Chung ; B. L. Gray; Large scale micropatterning of multi-walled carbon nanotube/polydimethylsiloxane nanocomposite polymer on highly flexible 12×24 inch substrates. Proc. SPIE 7926, Micromachining and Microfabrication Process Technology XVI, 79260L (February 15, 2011); doi:10.1117/12.876738. 6. A. Khosla, and Bonnie L. Gray. "(Invited) Micropatternable Multifunctional Nanocomposite Polymers for Flexible Soft NEMS and MEMS Applications." ECS Transactions 45.3 (2012): 477-494. doi: 10.1149/1.3700913 7. Khosla, Ajit. "Nanoparticle-doped electrically-conducting polymers for flexible nano-micro Systems." Electrochemical Society Interface 21.3-4 (2012): 67-70. 8. Ajit Khosla; Smart garments in chronic disease management: progress and challenges. Proc. SPIE 8548, Nanosystems in Engineering and Medicine, 85482O (October 24, 2012); doi:10.1117/12.979667. 9. D. Chung ; A. Khosla ; B. L. Gray; Screen printable flexible conductive nanocomposite polymer with applications to wearable sensors. Proc. SPIE 9060, Nanosensors, Biosensors, and Info-Tech Sensors and Systems 2014, 90600U (April 16, 2014); doi:10.1117/12.2046548. 10. Daehan Chung ; Sam Seyfollahi ; Ajit Khosla ; Bonnie Gray ; Ash Parameswaran ; Ramani Ramaseshan ; Kirpal Kohli; Initial experiments with flexible conductive electrodes for potential applications in cancer tissue screening. Proc. SPIE 7929, Microfluidics, BioMEMS, and Medical Microsystems IX, 79290Z (February 14, 2011); doi:10.1117/12.875563. 11. A. Khosla ; B. L. Gray; New technologies for large-scale micropatterning of functional nanocomposite polymers. Proc. SPIE 8344, Nanosensors, Biosensors, and Info-Tech Sensors and Systems 2012, 83440W (April 26, 2012); doi:10.1117/12.915178. 12. A. Khosla, B.L. Gray, Preparation, characterization and micromolding of multi-walled carbon nanotube polydimethylsiloxane conducting nanocomposite polymer, Materials Letters, Volume 63, Issues 13-14, 31 May 2009, Pages 1203-1206, ISSN 0167-577X, http://dx.doi.org/10.1016/j.matlet.2009.02.043. 13. Giassa, M., Khosla, A., Gray, B. et al. J Electron Test (2010) 26: 139. doi:10.1007/s10836-009-5125-3 14.Ozhikandathil, Jayan, Ajit Khosla, and Muthukumaran Packirisamy. "Electrically Conducting PDMS Nanocomposite Using In Situ Reduction of Gold Nanostructures and Mechanical Stimulation of Carbon Nanotubes and Silver Nanoparticles." ECS Journal of Solid State Science and Technology 4.10 (2015): S3048-S3052. doi:10.1149/2.0091510jss 15. Kassegne, Sam, Maria Vomero, Roberto Gavuglio, Mieko Hirabayashi, Emre Özyilmaz, Sebastien Nguyen, Jesus Rodriguez, Eda Özyilmaz, Pieter van Niekerk, and Ajit Khosla. "Electrical impedance, electrochemistry, mechanical stiffness, and hardness tunability in glassy carbon MEMS μECoG electrodes." Microelectronic Engineering 133 (2015): 36-44. 16. A. Khosla ; B. L. Gray; Fabrication and properties of conductive micromoldable thermosetting polymer for electronic routing in highly flexible microfluidic systems. Proc. SPIE 7593, Microfluidics, BioMEMS, and Medical Microsystems VIII, 759314 (February 17, 2010); doi:10.1117/12.840911.

  8. Measurement of Solid-State Optical Refrigeration by Two-Band Differential Luminescence Thermometry

    DTIC Science & Technology

    2010-03-01

    Bahae ,1 R. I . Epstein,2 and M. P. Hehlen2 1The University of New Mexico, 800 Yale Boulevard Northeast, Albuquerque, New Mexico 87131, USA 2Los Alamos...Solids, R. I . Epstein and M. Sheik- Bahae , eds. (Wiley, 2009), pp. 33–68. 3. W. M. Patterson, M. P. Hehlen, R. I . Epstein, and M. Sheik- Bahae ...M. Sheik- Bahae , R. I . Epstein, S. Bigotta, and M. Tonelli, “Cooling of Yb:YLF using cavity enhanced resonant absorption,” Proc. SPIE 6907, 69070B

  9. Advanced Numerical Methods for Simulating Nonlinear Multirate Lumped Parameter Models

    DTIC Science & Technology

    1991-05-01

    defining a Waveform: typedef struct Waveform char *name; /* character string of the name of the variable */ double tn; /* time of the beginning of the...A State-Space Approach, Reprinted from Proc. Third Ann. Allerton Conf. Circuits and Systems Thoery , 659-668, in Computer-Aided Circuit Design...kg/n 3) 1025.9 kg/m3 @ 15* C. v Kinematic Viscosity of Water (m2/sec) 1.19x10-6 m2/sec @ 15* C. G Acceleration of Gravity (m/sec2) 9.80665 m/sec 2 L

  10. Reactive Removal of BiF Ground State

    DTIC Science & Technology

    1990-09-28

    1978). 3. W E. Jones and T D. McLean, J. Mol. Spectrosc. 90, 481 (1981). 4. R. E Heidner, H . Helvajian , J. S. Holloway, and J. B. Koffend, J. Chem...Phys. 84, 2137 (1986). 5. C. R. Jones and H . P. Broida, J. Chem. Phys. 60, 4369 (1974). 6. H . Helvajian , J. S. Holloway, and J. B. Koffend, J. Chem...Phys. Rev. A6, 631 (1972). 27. H . Hotop and W C. Lineberger, J. Phys. Chem. Ref. Data 4, 539 (1985). 28. J.M. Herbelin, Conf. Proc., Intl. Gonf. on

  11. Performance Characterization and Optimization of Microgrid-Based Energy Generation and Storage Technologies

    DTIC Science & Technology

    2012-01-01

    A. Rufer, “Multiphysics and energetic modeling of a vanadium redox flow battery ,” in Proc. 2008 IEEE International Conference on Sustainable...p. 81. [11] K.W. Knehr and E.C. Kumbur, "Open circuit voltage of vanadium redox flow batteries : Discrepancy between models and experiments...Blanc and A. Rufer, “Multiphysics and energetic modeling of a vanadium redox flow battery ,” in Proc. 2008 IEEE International Conference on Sustainable

  12. Performance Analysis of Hybrid ARQ Protocols in a Slotted Code Division Multiple-Access Network

    DTIC Science & Technology

    1989-08-01

    Convolutional Codes . in Proc Int. Conf. Commun., 21.4.1-21.4.5, 1987. [27] J. Hagenauer. Rate Compatible Punctured Convolutional Codes . in Proc Int. Conf...achieved by using a low rate (r = 0.5), high constraint length (e.g., 32) punctured convolutional code . Code puncturing provides for a variable rate code ...investigated the use of convolutional codes in Type II Hybrid ARQ protocols. The error

  13. Pump Diode Characterization for an Unstable Diode-Pumped Alkali Laser Resonator

    DTIC Science & Technology

    2013-03-01

    2003. Petersen, A., and R. Lane, Second harmonic operation of diode-pumped Rb vapor lasers , Proc. of SPIE, 7005, 2008. Siegman , A. E., Lasers ...University Science Books, Sausalito, CA, 1986. Siegman , A. E., Defining, measuring and optimizing laser beam quality, Proc. of SPIE, 1868, 1993. Steck, D...PUMP DIODE CHARACTERIZATION FOR AN UNSTABLE DIODE-PUMPED ALKALI LASER RESONATOR THESIS Chad T. Taguba, Master Sergeant, USAF AFIT-ENP-13-M-33

  14. Blood Organic Phosphate in Hyperthermic Dogs

    DTIC Science & Technology

    1959-06-01

    fermenting uptake is then responsible for the previously yeast caused an increase in fezrmentation and a observed fall in plasma inorganic phosphate in...Young. The alcoholic 3. Radigan, L. R., and S. Robinson. Effects of ferment of yast- juice . Proc. Roy. Soc. London environmental heat stress and...4. Kenny, R. A. The effect of hot, humid environ- yeast - juice from hexose and phosphate. Proc. ments on the renal function of West Africans. Roy Soc

  15. Polarization Orientation Dependence of the Far Infrared Spectra of Oriented Single Crystals of 1,3,5-trinitro-S-triazine (RDX) using Terahertz Time-Domain Spectroscopy

    DTIC Science & Technology

    2009-01-01

    BE, Hogbin MR, Kemp MC (2007) Proc IEEE 95:1559 14. Laman N, Sree Harsha S, Grischkowsky D, Melinger JS (2008) Opt Express 16:4094 15. Melinger JS... Laman N, Grischkowsky D (2008) Appl Phy Lett 93:011102 16. Tribe WR, Newnham DA, Taday PF, Kemp MC (2004) Proc SPIE 5354:168 17. Watters DG, Falconer DG

  16. Microsoft Research at TREC 2009. Web and Relevance Feedback Tracks

    DTIC Science & Technology

    2009-11-01

    Information Processing Systems, pages 193–200, 2006. [2] J . M. Kleinberg. Authoritative sources in a hyperlinked environment. In Proc. of the 9th...Walker, S. Jones, M. Hancock-Beaulieu, and M. Gatford. Okapi at TREC-3. In Proc. of the 3rd Text REtrieval Conference, 1994. [8] J . J . Rocchio. Relevance...feedback in information retrieval. In Gerard Salton , editor, The SMART Retrieval System - Experiments in Automatic Document Processing. Prentice Hall

  17. Nanocomposites for Enhanced Structural Integrity

    DTIC Science & Technology

    2007-09-11

    Yong and H.T. Hahn, "Kevlar/Vinyl Ester Composites with SiC Nanoparticles ," SAMPE 2004 Proc. ( CD ROM), May 2004. C-6. M. Lui and H.T. Hahn...34 Nanoparticle -Based Mitigation of fiber Print-Through in Composite Mirrors," Proc. American Society for Composites, 20’h Technical Conference ( CD ROM), Sept. 2005...the graphene layers. Microwave radiation aids in drying and results in further separation of the sheets. Thermogravimetric analysis indicates that the

  18. Security Games Applied to Real-World: Research Contributions and Challenges

    DTIC Science & Technology

    2012-01-01

    Marecki, J.: GUARDS and PROTECT: Next Generation Applications of Security Games . SIGECOM 10 (March 2011) 31–34 4. Shieh, E ., An, B., Yang, R., Tambe...Steigerwald, E .: GUARDS - Game Theoretic Security Allocation on a National Scale. In: Proc. of The 10th International Conference on Autonomous Agents...Shieh, E ., Kiekintveld, C.: Refinement of Strong Stackelberg Equilibria in Security Games . In: Proc. of the 25th Conference on Artificial Intelligence

  19. Spectral Analysis of Breast Cancer on Tissue Microarrays: Seeing Beyond Morphology

    DTIC Science & Technology

    2005-04-01

    Harvey N., Szymanski J.J., Bloch J.J., Mitchell M. investigation of image feature extraction by a genetic algorithm. Proc. SPIE 1999;3812:24-31. 11...automated feature extraction using multiple data sources. Proc. SPIE 2003;5099:190-200. 15 4 Spectral-Spatial Analysis of Urine Cytology Angeletti et al...Appendix Contents: 1. Harvey, N.R., Levenson, R.M., Rimm, D.L. (2003) Investigation of Automated Feature Extraction Techniques for Applications in

  20. Ground Motion Studies for Large Future Accelerator

    NASA Astrophysics Data System (ADS)

    Takeda, Shigeru; Oide, Katsunobu

    1997-05-01

    The future large accelerator, such as TeV linear collider, should have extremely small emittance to perform the required luminosity. Precise alignment of machine components is essential to prevent emittance dilution. The ground motion spoils alignment of accelerator elements and results in emittance growth. The ground motion in the frequency range of seismic vibration is mostly coherent in the related accelerator. But the incoherent diffusive or Brownian like motion becomes dominant at frequency region less than seismic vibration [1, 2, 3]. Slow ground motion with respect to the machine performance is discussed including the method of tunnel construction. Our experimental results and recent excavated results clarify that application of TBMs is better excavating method than NATM (Drill + Blast) for accelerator tunnel to prevent emittance dilution. ([1] V. Shiltsev, Proc. of IWAA95 Tsukuba, 1995. [2] Shigeru Takeda et al., Proc. of EPAC96, 1996. [3] A. Sery, Proc. of LINAC96, 1996.)

  1. Phospholamban and its Phosphorylated Form Interact Differently with Lipid Bilayers: A 31P, 2H and 13C Solid-State NMR Spectroscopic Study

    PubMed Central

    Abu-Baker, Shadi; Lorigan, Gary A.

    2008-01-01

    Phospholamban (PLB) is a 52-amino acid integral membrane protein that helps to regulate the flow of Ca2+ ions in cardiac muscle cells. Recent structural studies on the PLB pentamer and the functionally active monomer (AFA-PLB) debate whether its cytoplasmic domain, in either the phosphorylated or dephosphorylated states, is α-helical in structure as well as whether it associates with the lipid head groups [Oxenoid, K. (2005) Proc Natl. Acad. Sci. USA 102, 10870–10875, Karim, C. B. (2004) Proc. Natl. Acad. Sci. USA 101, 14437–14442, Andronesi, C.A. (2005) J. Am. Chem. Soc. 127, 12965–12974, Li, J. (2003) Biochemistry 42, 10674–10682, Metcalfe, E. E. (2005) Biochemistry 44, 4386–4396, Clayton, J. C. (2005) Biochemistry 44, 17016–17026]. Comparing the secondary structure of the PLB pentamer and its phosphorylated form (P-PLB) as well as their interaction with the lipid bilayer is crucial in order to understand its regulatory function. Therefore, in this study, the full-length wild-type (WT)-PLB and P-PLB were incorporated into 1-palmitoyl-2-oleoyl-sn-glycero-phosphocholine (POPC) phospholipid bilayers and studied utilizing solid-state NMR spectroscopy. The analysis of the 2H and 31P solid-state NMR data of PLB and P-PLB in POPC multilamellar vesicles (MLVs) indicates that a direct interaction takes place between both proteins and the phospholipid head groups. However, the interaction of P-PLB with POPC bilayers was less significant when compared to PLB. Moreover, the secondary structure using 13C=O site-specific isotopically labeled Ala15-PLB and Ala15-P-PLB in POPC bilayers suggests that this residue, located in the cytoplasmic domain, is a part of an α-helical structure for both PLB and P-PLB. PMID:17073452

  2. KENNEDY SPACE CENTER, FLA. - Stephanie Stilson, NASA vehicle manager for Discovery, is being filmed for a special feature on the KSC Web about the recent Orbiter Major Modification period, which included inspection, modifications and reservicing of most systems onboard Discovery, plus installation of a Multifunction Electronic Display Subsystem (MEDS) - a state-of-the-art “glass cockpit.” The orbiter is now being prepared for eventual launch on a future mission.

    NASA Image and Video Library

    2004-01-22

    KENNEDY SPACE CENTER, FLA. - Stephanie Stilson, NASA vehicle manager for Discovery, is being filmed for a special feature on the KSC Web about the recent Orbiter Major Modification period, which included inspection, modifications and reservicing of most systems onboard Discovery, plus installation of a Multifunction Electronic Display Subsystem (MEDS) - a state-of-the-art “glass cockpit.” The orbiter is now being prepared for eventual launch on a future mission.

  3. Quadratic Zeeman effect in hydrogen Rydberg states: Rigorous bound-state error estimates in the weak-field regime

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Falsaperla, P.; Fonte, G.

    1993-05-01

    Applying a method based on some results due to Kato [Proc. Phys. Soc. Jpn. 4, 334 (1949)], we show that series of Rydberg eigenvalues and Rydberg eigenfunctions of hydrogen in a uniform magnetic field can be calculated with a rigorous error estimate. The efficiency of the method decreases as the eigenvalue density increases and as [gamma][ital n][sup 3][r arrow]1, where [gamma] is the magnetic-field strength in units of 2.35[times]10[sup 9] G and [ital n] is the principal quantum number of the unperturbed hydrogenic manifold from which the diamagnetic Rydberg states evolve. Fixing [gamma] at the laboratory value 2[times]10[sup [minus]5] andmore » confining our calculations to the region [gamma][ital n][sup 3][lt]1 (weak-field regime), we obtain extremely accurate results up to states corresponding to the [ital n]=32 manifold.« less

  4. Fla. Budget Threatens Online Ed. Mandate

    ERIC Educational Resources Information Center

    Manzo, Kathleen Kennedy

    2009-01-01

    As Florida school districts scramble to meet a looming state mandate to offer full-time online instruction for K-8 students, and as high school enrollments in such courses continue to climb, lawmakers are mulling restrictions and budget cuts for the state's nationally known virtual school. Together, online-learning advocates say, the growing…

  5. A High Performance Frequency Standard and Distribution System for Cassini Ka-Band Experiment

    DTIC Science & Technology

    2005-08-01

    Orthogonal Polarization In Anisotropic Dielectric Resonators”, Proceedings of the 2002 IEEE International Frequency Control Symposium , pp. 553-558...2002. [9] G. J. Dick, Rabi T. Wang, Robert Tjoelker, “Design and Progress Report for Compact Cryocooled Sapphire Oscillator "VCSO"”, Proc. 2005 Joint...IEEE FCS/ PTTI. [10] R. Basu, G. J. Dick, Rabi T. Wang,” Novel Design of an All- Cryogenic RF Pound Circuit “,Proc. 2005 Joint IEEE FCS/ PTTI

  6. Hierarchical Organization for Large, Dynamic Radio Networks.

    DTIC Science & Technology

    1988-01-01

    January 1985. [3] N. Shacharm and J. Tornow . Future Directions in Packet Radio Technology. In - Proc. of IEEE INFOCOM󈨙, Washington, D.C., 1985. [4] J.J...Freeman and Company, 1979. [7] J. Jubin and J. Tornow . The DARPA Packet Radio Network Protocols. Proceed- inga of the IEEE, 75(1):21-32, January 1987... Tornow . Future Directions in Packet Radio Technology. In Proc. of IEEE INFOCOM󈨙, Washington, D.C., 1985. [28] N. Shacham and J. Westcott. Future

  7. Coherent Structures and Chaos Control in High-Power Microwave and Charged-Particle Beam Devices

    DTIC Science & Technology

    2009-01-31

    34Equilibrium Theory of an Intense Elliptic Beam for High - Power Ribbon-Beam Klystron Applications," Proc. 2007 Part. Accel. Conf. p. 2316. Courant...34Equilibrium Theory of an Intense Elliptic Beam for High - Power Ribbon-Beam Klystron Applications," C. Chen and J. Zhou, Proc. 2007 Part. Accel. Conf. (2007...accelerator focusing systems. Over 600 high - power , high -efficiency klystrons , for example, may be needed to provide rf power for the acceleration

  8. An Experimental and Theoretical Investigation of Optogalvanic Effects.

    DTIC Science & Technology

    1987-12-01

    Discharge Plasmas" at Atholl Palace Hotel, Pitlochry, Scotland, June 23-July 5 (1985). Published in Radiative Processes in Discharge Plasmas, edited by J...and 8 are taken from Phelps.39 The temperature dependence of D is taken from Buckingham and Dalgarno, that of Y is taken from Allison, Browne and...1307 (1955). 40. R. A. Buckingham , and A. Dalgarno, Proc. Roy. Soc. (London) A213, 506 (1952). 41. D. C. Allison, J. C. Browne, and A. Dalgarno, Proc

  9. URREF Reliability Versus Credibility in Information Fusion

    DTIC Science & Technology

    2013-07-01

    Fusion, Vol. 3, No. 2, December, 2008. [31] E. Blasch, J. Dezert, and P. Valin , “DSMT Applied to Seismic and Acoustic Sensor Fusion,” Proc. IEEE Nat...44] E. Blasch, P. Valin , E. Bossé, “Measures of Effectiveness for High- Level Fusion,” Int. Conference on Information Fusion, 2010. [45] X. Mei, H...and P. Valin , “Information Fusion Measures of Effectiveness (MOE) for Decision Support,” Proc. SPIE 8050, 2011. [49] Y. Zheng, W. Dong, and E

  10. Knowledge-Based Vision Techniques for the Autonomous Land Vehicle Program

    DTIC Science & Technology

    1991-10-01

    Knowledge System The CKS is an object-oriented knowledge database that was originally designed to serve as the central information manager for a...34 Representation Space: An Approach to the Integra- tion of Visual Information ," Proc. of DARPA Image Understanding Workshop, Palo Alto, CA, pp. 263-272, May 1989...Strat, " Information Management in a Sensor-Based Au- tonomous System," Proc. DARPA Image Understanding Workshop, University of Southern CA, Vol.1, pp

  11. The nucleotide-dependent interaction of FlaH and FlaI is essential for assembly and function of the archaellum motor

    DOE PAGES

    Chaudhury, Paushali; Neiner, Tomasz; D'Imprima, Edoardo; ...

    2015-10-28

    The motor of the membrane-anchored archaeal motility structure, the archaellum, contains FlaX, FlaI and FlaH. FlaX forms a 30 nm ring structure that acts as a scaffold protein and was shown to interact with the bifunctional ATPase FlaI and FlaH. However, the structure and function of FlaH has been enigmatic. Here we present structural and functional analyses of isolated FlaH and archaellum motor subcomplexes. The FlaH crystal structure reveals a RecA/Rad51 family fold with an ATP bound on a conserved and exposed surface, which presumably forms an oligomerization interface. FlaH does not hydrolyze ATP in vitro, but ATP binding tomore » FlaH is essential for its interaction with FlaI and for archaellum assembly. FlaH interacts with the C-terminus of FlaX, which was earlier shown to be essential for FlaX ring formation and to mediate interaction with FlaI. Electron microscopy reveals that FlaH assembles as a second ring inside the FlaX ring in vitro. Collectively these data reveal central structural mechanisms for FlaH interactions in mediating archaellar assembly: FlaH binding within the FlaX ring and nucleotide-regulated FlaH binding to FlaI form the archaellar basal body core.« less

  12. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Chaudhury, Paushali; Neiner, Tomasz; D'Imprima, Edoardo

    The motor of the membrane-anchored archaeal motility structure, the archaellum, contains FlaX, FlaI and FlaH. FlaX forms a 30 nm ring structure that acts as a scaffold protein and was shown to interact with the bifunctional ATPase FlaI and FlaH. However, the structure and function of FlaH has been enigmatic. Here we present structural and functional analyses of isolated FlaH and archaellum motor subcomplexes. The FlaH crystal structure reveals a RecA/Rad51 family fold with an ATP bound on a conserved and exposed surface, which presumably forms an oligomerization interface. FlaH does not hydrolyze ATP in vitro, but ATP binding tomore » FlaH is essential for its interaction with FlaI and for archaellum assembly. FlaH interacts with the C-terminus of FlaX, which was earlier shown to be essential for FlaX ring formation and to mediate interaction with FlaI. Electron microscopy reveals that FlaH assembles as a second ring inside the FlaX ring in vitro. Collectively these data reveal central structural mechanisms for FlaH interactions in mediating archaellar assembly: FlaH binding within the FlaX ring and nucleotide-regulated FlaH binding to FlaI form the archaellar basal body core.« less

  13. Challenges of anamorphic high-NA lithography and mask making

    NASA Astrophysics Data System (ADS)

    Hsu, Stephen D.; Liu, Jingjing

    2017-06-01

    Chip makers are actively working on the adoption of 0.33 numerical aperture (NA) EUV scanners for the 7-nm and 5-nm nodes (B. Turko, S. L. Carson, A. Lio, T. Liang, M. Phillips, et al., in `Proc. SPIE9776, Extreme Ultraviolet (EUV) Lithography VII', vol. 977602 (2016) doi: 10.1117/12.2225014; A. Lio, in `Proc. SPIE9776, Extreme Ultraviolet (EUV) Lithography VII', vol. 97760V (2016) doi: 10.1117/12.2225017). In the meantime, leading foundries and integrated device manufacturers are starting to investigate patterning options beyond the 5-nm node (O. Wood, S. Raghunathan, P. Mangat, V. Philipsen, V. Luong, et al., in `Proc. SPIE. 9422, Extreme Ultraviolet (EUV) Lithography VI', vol. 94220I (2015) doi: 10.1117/12.2085022). To minimize the cost and process complexity of multiple patterning beyond the 5-nm node, EUV high-NA single-exposure patterning is a preferred method over EUV double patterning (O. Wood, S. Raghunathan, P. Mangat, V. Philipsen, V. Luong, et al., in `Proc. SPIE. 9422, Extreme Ultraviolet (EUV) Lithography VI', vol. 94220I (2015) doi: 10.1117/12.2085022; J. van Schoot, K. van Ingen Schenau, G. Bottiglieri, K. Troost, J. Zimmerman, et al., `Proc. SPIE. 9776, Extreme Ultraviolet (EUV) Lithography VII', vol. 97761I (2016) doi: 10.1117/12.2220150). The EUV high-NA scanner equipped with a projection lens of 0.55 NA is designed to support resolutions below 10 nm. The high-NA system is beneficial for enhancing resolution, minimizing mask proximity correction bias, improving normalized image log slope (NILS), and controlling CD uniformity (CDU). However, increasing NA from 0.33 to 0.55 reduces the depth of focus (DOF) significantly. Therefore, the source mask optimization (SMO) with sub-resolution assist features (SRAFs) are needed to increase DOF to meet the demanding full chip process control requirements (S. Hsu, R. Howell, J. Jia, H.-Y. Liu, K. Gronlund, et al., EUV `Proc. SPIE9048, Extreme Ultraviolet (EUV) Lithography VI', (2015) doi: 10.1117/12.2086074). To ensure no assist feature printing, the assist feature sizes need to be scaled with λ/NA. The extremely small SRAF width (below 25 nm on the reticle) is difficult to fabricate across the full reticle. In this paper, we introduce an innovative `attenuated SRAF' to improve SRAF manufacturability and still maintain the process window benefit. A new mask fabrication process is proposed to use existing mask-making capability to manufacture the attenuated SRAFs. The high-NA EUV system utilizes anamorphic reduction; 4× in the horizontal (slit) direction and 8× in the vertical (scanning) direction (J. van Schoot, K. van Ingen Schenau, G. Bottiglieri, K. Troost, J. Zimmerman, et al., `Proc. SPIE. 9776, Extreme Ultraviolet (EUV) Lithography VII', vol. 97761I (2016) doi: 10.1117/12.2220150; B. Kneer, S. Migura, W. Kaiser, J. T. Neumann, J. van Schoot, in `Proc. SPIE9422, Extreme Ultraviolet (EUV) Lithography VI', vol. 94221G (2015) doi: 10.1117/12.2175488). For an anamorphic system, the magnification has an angular dependency, and thus, familiar mask specifications such as mask error factor (MEF) need to be redefined. Similarly, mask-manufacturing rule check (MRC) needs to consider feature orientation.

  14. Selection of Human Antibody Fragments Which Bind Novel Breast Tumor Antigens

    DTIC Science & Technology

    1998-09-01

    chain Fv analogue produced in Escherichia coli. Proc Natl Acad Sci U S A. 85: 5879-83. 11. Adams, G.P., McCartney, J.E., Tai, M.-S., Oppermann, H...antidigoxin single-chain Fv analogue produced in E coil. Proc NailAcadSci Bernard Foundation, the Frank Strick Foundation and the USA 85:5879-5883 CaPCURE...recovery of infectious phage was increased by preincubation of cells with chloroquine . Measurement of phage recovery from within the cytosol as a

  15. Interfacial Layer Effects in Ba(1-x)Sr(x)TiO3 Thick Films Prepared by Plasma Spray

    DTIC Science & Technology

    2003-04-01

    in Materials Development for Direct Write technologies, edited by D. B. Chrisey, D. R. Gamota, H . Helvajian , and D. P. Taylor, (Mater. Res. Soc. Proc...Direct Write technologies, edited by D. B. Chrisey, D. R. Gamota, H . Helvajian , and D. P. Taylor, (Mater. Res. Soc. Proc. 624, San Francisco, CA, 2000...Research Center at Northwestern University supported by the MRSEC program under a NSF grant (DMR-0076097). REFERENCES 1. K. H . Church, C. Fore, T. Feeley

  16. System M: A Program Logic for Code Sandboxing and Identification

    DTIC Science & Technology

    2014-07-22

    M. Ryan. Attack, solution and verification for shared authorisation data in TCG TPM. In Proc. FAST’09, 2010. [8] A. Datta, A. Derek, J. C. Mitchell...11] S. Delaune, S. Kremer, M. D. Ryan, and G. Steel. A formal analysis of authentication in the TPM. In Proc. FAST’10, 2011. [12] S. Delaune, S...A. Jeffrey. Authenticity by typing for security protocols. Journal of Computer Security, 11(4):451–519, July 2003. [16] S. Gürgens, C. Rudolph, D

  17. A Guide to Electrical Insulation Design in Aerospace Vehicles for a Broad Range of Environmental Parameter Space

    DTIC Science & Technology

    2010-03-01

    as an example with information from Llewellyn Jones (1939) [30] and from Meek (1978), pg. 233 [7]. Morokuma (1969) [31] varied the surface potential...breakdown in high pressure gases,” Phys. Rev. A, 21, 2069. 13. Dutton, J., Llewellyn Jones , F., and Palmer, R.W., (1961), Proc. Phys. Soc. 78, 569...breakdown and insulators in compressed gas,” IEE Proc. 128, 303. 30. Llewellyn Jones , F. (1939), Phil. Mag. 28, 192. 31. Morokuma, Y., Nakamura, Y., and

  18. Regulation & Development of Membrane Transport Processes.

    DTIC Science & Technology

    1985-05-15

    221, 733-741. 30. Liu, A. Y. C. and Greengard, P. (1974) Proc. Nall. Acad. Sci. USA, 71, 3869-3873. 31. MacKnight, A. D. C., DiBona , D. R., and Leaf...However, DiBona and Sachs and their collaborators 2. IXO(YI’(YI’IC INSEITION OF OTHER TANSPORT SYSTEMS 155 have challenged this view, suggesting that...the U.S. Public Health Service. REFERENCES I. DiBona , D. R., Ito, S., Berglindh, T.. and Sachs, G. (1979) Proc. Nall. Acad. Sci. USA, 76, 6689-6693. 2

  19. A Lightweight Intelligent Virtual Cinematography System for Machinima Production

    DTIC Science & Technology

    2007-01-01

    portmanteau of machine and cinema , machinima refers to the innovation of leveraging video game technology to greatly ease the creation of computer...selecting camera angles to capture the action of an a priori unknown script as aesthetically appropriate cinema . There are a number of challenges therein...Proc. of the 4th International Conf. on Autonomous Agents. Young, R.M. and Riedl, M.O. 2003. Towards an Architecture for Intelligent Control of Narrative in Interactive Virtual Worlds. In Proc. of IUI 2003.

  20. Implementation of a Fault Tolerant Control Unit within an FPGA for Space Applications

    DTIC Science & Technology

    2006-12-01

    Conference 2002, September 2002. [20] M. Alderighi, A. Candelori, F. Casini, S. D’Angelo, M. Mancini, A. Paccagnella, S. Pastore , G.R. Sechi, “Heavy...Luigi Carro and Ricardo Reis , “Designing and Testing Fault-Tolerant Techniques for SRAM-based FPGAs,” in Proc. 1st Conference on Computer Frontiers, pp...susceptibility,” in IEEE Proc. 12th IEEE Intl. Symposium on On-Line Testing, pp. 89-91, 2006. [45] Fernanda Lima, Luigi Carro and Ricardo Reis

  1. Electron temperature response to ECRH on FTU tokamak in transient conditions.

    NASA Astrophysics Data System (ADS)

    Jacchia, A.; Bruschi, A.; Cirant, S.; Granucci, G.; Sozzi, C.; de Luca, F.; Amadeo, P.; Bracco, G.; Tudisco, O.

    2001-10-01

    Steady-state electron heat transport analysis of FTU high density plasmas under Electron Cyclotron Heating (ECRH) shows "stiff" electron temperature profiles [1,2,3]. Plasma response to off-axis EC heating, in fact, exibits a lower limit to electron temperature gradient length, Lc , below which electron thermal conductivity switches to higher values. Stiffness, however, is attenuated in the plasma core of saw-tooth free discharges with flat-hollow temperature profile and during current ramp-up [3,4,5], in which cases the temperature gradient length can be brought to very low values by means of on-axis ECH. Steady and current ramp-up discharges probed by steady and modulated ECH are analyzed in terms of stiffnes. Critical gradient length dependence on local features of computed current density profile is discussed. [1] Sozzi, C. et al., Paper EXP5/13, Plasma Phys. Contr. Fus. Res., Proc.18th IAEA Conf., Sorrento, 2000. [2] Jacchia, A. et al. Topical Conference on Radio Frequency Power in Plasmas, Oxnard, USA, (2001). [3] Cirant, S. et al. Topical Conference on Radio Frequency Power in Plasmas, Oxnard, USA, (2001). [4] Sozzi, C. et al., EPS, Madeira 2001. [5] Bracco, G. et al.,Plasma Phys. Contr. Fus. Res., Proc.18th IAEA Conf., Sorrento, 2000.

  2. KSC-2010-4654

    NASA Image and Video Library

    2010-09-15

    CAPE CANAVERAL, Fla. -- NASA's Kennedy Space Center and Brevard Workforce host a job fair in Kennedy's Operations Support Building II and Space Station Processing Facility to help center employees with future planning and placement as the Space Shuttle Program comes to an end. Recruiters included federal, state and local government agencies and organizations, as well as private companies from across the country. The second part of the job fair is scheduled for Sept. 16 at a hotel in Cape Canaveral, Fla. Kennedy's Human Resources Office also has hosted workshops, seminars and other events to prepare employees as much as possible for future opportunities. Photo credit: NASA/Kim Shiflett

  3. KSC-2010-4652

    NASA Image and Video Library

    2010-09-15

    CAPE CANAVERAL, Fla. -- NASA's Kennedy Space Center and Brevard Workforce host a job fair in Kennedy's Operations Support Building II and Space Station Processing Facility to help center employees with future planning and placement as the Space Shuttle Program comes to an end. Recruiters included federal, state and local government agencies and organizations, as well as private companies from across the country. The second part of the job fair is scheduled for Sept. 16 at a hotel in Cape Canaveral, Fla. Kennedy's Human Resources Office also has hosted workshops, seminars and other events to prepare employees as much as possible for future opportunities. Photo credit: NASA/Kim Shiflett

  4. KSC-2010-4659

    NASA Image and Video Library

    2010-09-16

    CAPE CANAVERAL, Fla. -- NASA's Kennedy Space Center and Brevard Workforce host a job fair at a hotel in Cape Canaveral, Fla., to help center employees with future planning and placement as the Space Shuttle Program comes to an end. Recruiters included federal, state and local government agencies and organizations, as well as private companies from across the country. The first part of the job fair took place Sept. 15 in Kennedy's Operations Support Building II and Space Station Processing Facility. Kennedy's Human Resources Office also has hosted workshops, seminars and other events to prepare employees as much as possible for future opportunities. Photo credit: NASA/Jack Pfaller

  5. KSC-2010-4653

    NASA Image and Video Library

    2010-09-15

    CAPE CANAVERAL, Fla. -- NASA's Kennedy Space Center and Brevard Workforce host a job fair in Kennedy's Operations Support Building II and Space Station Processing Facility to help center employees with future planning and placement as the Space Shuttle Program comes to an end. Recruiters included federal, state and local government agencies and organizations, as well as private companies from across the country. The second part of the job fair is scheduled for Sept. 16 at a hotel in Cape Canaveral, Fla. Kennedy's Human Resources Office also has hosted workshops, seminars and other events to prepare employees as much as possible for future opportunities. Photo credit: NASA/Kim Shiflett

  6. KSC-2010-4657

    NASA Image and Video Library

    2010-09-16

    CAPE CANAVERAL, Fla. -- NASA's Kennedy Space Center and Brevard Workforce host a job fair at a hotel in Cape Canaveral, Fla., to help center employees with future planning and placement as the Space Shuttle Program comes to an end. Recruiters included federal, state and local government agencies and organizations, as well as private companies from across the country. The first part of the job fair took place Sept. 15 in Kennedy's Operations Support Building II and Space Station Processing Facility. Kennedy's Human Resources Office also has hosted workshops, seminars and other events to prepare employees as much as possible for future opportunities. Photo credit: NASA/Jack Pfaller

  7. KSC-2010-4658

    NASA Image and Video Library

    2010-09-16

    CAPE CANAVERAL, Fla. -- NASA's Kennedy Space Center and Brevard Workforce host a job fair at a hotel in Cape Canaveral, Fla., to help center employees with future planning and placement as the Space Shuttle Program comes to an end. Recruiters included federal, state and local government agencies and organizations, as well as private companies from across the country. The first part of the job fair took place Sept. 15 in Kennedy's Operations Support Building II and Space Station Processing Facility. Kennedy's Human Resources Office also has hosted workshops, seminars and other events to prepare employees as much as possible for future opportunities. Photo credit: NASA/Jack Pfaller

  8. KSC-2010-4656

    NASA Image and Video Library

    2010-09-15

    CAPE CANAVERAL, Fla. -- NASA's Kennedy Space Center and Brevard Workforce host a job fair in Kennedy's Operations Support Building II and Space Station Processing Facility to help center employees with future planning and placement as the Space Shuttle Program comes to an end. Recruiters included federal, state and local government agencies and organizations, as well as private companies from across the country. The second part of the job fair is scheduled for Sept. 16 at a hotel in Cape Canaveral, Fla. Kennedy's Human Resources Office also has hosted workshops, seminars and other events to prepare employees as much as possible for future opportunities. Photo credit: NASA/Kim Shiflett

  9. KSC-2010-4655

    NASA Image and Video Library

    2010-09-15

    CAPE CANAVERAL, Fla. -- NASA's Kennedy Space Center and Brevard Workforce host a job fair in Kennedy's Operations Support Building II and Space Station Processing Facility to help center employees with future planning and placement as the Space Shuttle Program comes to an end. Recruiters included federal, state and local government agencies and organizations, as well as private companies from across the country. The second part of the job fair is scheduled for Sept. 16 at a hotel in Cape Canaveral, Fla. Kennedy's Human Resources Office also has hosted workshops, seminars and other events to prepare employees as much as possible for future opportunities. Photo credit: NASA/Kim Shiflett

  10. KSC01padig109

    NASA Image and Video Library

    2001-03-02

    Student teams direct their robots on the playing field during the NASA/KSC FIRST Southeastern Regional event held March 1-3, 2001. Robot number 582 is by the Viking Electros, W.M. Raines High School, Jacksonville, Fla. Number 459 is by Eastside High School, Gainesville, Fla. FIRST (For Inspiration and Recognition of Science and Technology) events are held nationwide, pitting robots against each other and the clock on a playing field. Many teams are sponsored by corporations and academic institutions. There are 27 teams throughout the State of Florida who are competing. KSC, which sponsors nine teams, has held the regional event for two years

  11. KENNEDY SPACE CENTER, FLA. - The Space Life Sciences Lab (SLSL), formerly known as the Space Experiment Research and Processing Laboratory (SERPL), is nearing completion. The new lab is a state-of-the-art facility being built for ISS biotechnology research. Developed as a partnership between NASA-KSC and the State of Florida, NASA’s life sciences contractor will be the primary tenant of the facility, leasing space to conduct flight experiment processing and NASA-sponsored research. About 20 percent of the facility will be available for use by Florida’s university researchers through the Florida Space Research Institute.

    NASA Image and Video Library

    2003-09-10

    KENNEDY SPACE CENTER, FLA. - The Space Life Sciences Lab (SLSL), formerly known as the Space Experiment Research and Processing Laboratory (SERPL), is nearing completion. The new lab is a state-of-the-art facility being built for ISS biotechnology research. Developed as a partnership between NASA-KSC and the State of Florida, NASA’s life sciences contractor will be the primary tenant of the facility, leasing space to conduct flight experiment processing and NASA-sponsored research. About 20 percent of the facility will be available for use by Florida’s university researchers through the Florida Space Research Institute.

  12. 50 CFR 216.50 - Importation at designated ports.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ..., designated ports of entry for the United States are: New York, N.Y. Miami, Fla. Chicago, Ill. San Francisco, Calif. Los Angeles, Calif. New Orleans, La. Seattle, Wash. Honolulu, Hi. (c) Additionally, marine...

  13. KENNEDY SPACE CENTER, FLA. - From left, Bob McLean, Southwest Texas State University, and Valerie Cassanto, Instrumentation Technology Associates, Inc., study one of the experiments carried on mission STS-107. Several experiments were found during the search for Columbia debris. Included in the Commercial ITA Biomedical Experiments payload on mission STS-107 are urokinase cancer research, microencapsulation of drugs, the Growth of Bacterial Biofilm on Surfaces during Spaceflight (GOBBSS), and tin crystal formation.

    NASA Image and Video Library

    2003-05-07

    KENNEDY SPACE CENTER, FLA. - From left, Bob McLean, Southwest Texas State University, and Valerie Cassanto, Instrumentation Technology Associates, Inc., study one of the experiments carried on mission STS-107. Several experiments were found during the search for Columbia debris. Included in the Commercial ITA Biomedical Experiments payload on mission STS-107 are urokinase cancer research, microencapsulation of drugs, the Growth of Bacterial Biofilm on Surfaces during Spaceflight (GOBBSS), and tin crystal formation.

  14. Method and system for turbomachinery surge detection

    DOEpatents

    Faymon, David K.; Mays, Darrell C.; Xiong, Yufei

    2004-11-23

    A method and system for surge detection within a gas turbine engine, comprises: measuring the compressor discharge pressure (CDP) of the gas turbine over a period of time; determining a time derivative (CDP.sub.D ) of the measured (CDP) correcting the CDP.sub.D for altitude, (CDP.sub.DCOR); estimating a short-term average of CDP.sub.DCOR.sup.2 ; estimating a short-term average of CDP.sub.DCOR ; and determining a short-term variance of corrected CDP rate of change (CDP.sub.roc) based upon the short-term average of CDP.sub.DCOR and the short-term average of CDP.sub.DCOR.sup.2. The method and system then compares the short-term variance of corrected CDP rate of change with a pre-determined threshold (CDP.sub.proc) and signals an output when CDP.sub.roc >CDP.sub.proc. The method and system provides a signal of a surge within the gas turbine engine when CDP.sub.roc remains>CDP.sub.proc for pre-determined period of time.

  15. A comparison of methods of fitting several models to nutritional response data.

    PubMed

    Vedenov, D; Pesti, G M

    2008-02-01

    A variety of models have been proposed to fit nutritional input-output response data. The models are typically nonlinear; therefore, fitting the models usually requires sophisticated statistical software and training to use it. An alternative tool for fitting nutritional response models was developed by using widely available and easier-to-use Microsoft Excel software. The tool, implemented as an Excel workbook (NRM.xls), allows simultaneous fitting and side-by-side comparisons of several popular models. This study compared the results produced by the tool we developed and PROC NLIN of SAS. The models compared were the broken line (ascending linear and quadratic segments), saturation kinetics, 4-parameter logistics, sigmoidal, and exponential models. The NRM.xls workbook provided results nearly identical to those of PROC NLIN. Furthermore, the workbook successfully fit several models that failed to converge in PROC NLIN. Two data sets were used as examples to compare fits by the different models. The results suggest that no particular nonlinear model is necessarily best for all nutritional response data.

  16. Exact Solution of a Two-Species Quantum Dimer Model for Pseudogap Metals

    NASA Astrophysics Data System (ADS)

    Feldmeier, Johannes; Huber, Sebastian; Punk, Matthias

    2018-05-01

    We present an exact ground state solution of a quantum dimer model introduced by Punk, Allais, and Sachdev [Quantum dimer model for the pseudogap metal, Proc. Natl. Acad. Sci. U.S.A. 112, 9552 (2015)., 10.1073/pnas.1512206112], which features ordinary bosonic spin-singlet dimers as well as fermionic dimers that can be viewed as bound states of spinons and holons in a hole-doped resonating valence bond liquid. Interestingly, this model captures several essential properties of the metallic pseudogap phase in high-Tc cuprate superconductors. We identify a line in parameter space where the exact ground state wave functions can be constructed at an arbitrary density of fermionic dimers. At this exactly solvable line the ground state has a huge degeneracy, which can be interpreted as a flat band of fermionic excitations. Perturbing around the exactly solvable line, this degeneracy is lifted and the ground state is a fractionalized Fermi liquid with a small pocket Fermi surface in the low doping limit.

  17. May quasicrystals be good thermoelectric materials?

    NASA Astrophysics Data System (ADS)

    Maciá, Enrique

    2000-11-01

    We present a theoretical analysis of quasicrystals (QCs) as potential thermoelectric materials. We consider a self-similar density of states model and extend the framework introduced in [G. D. Mahan and J. O. Sofo, Proc. Natl. Acad. Sci. U.S.A. 93, 7436 (1996)] to systems exhibiting correlated features in their electronic structure. We show that relatively high values of the thermoelectric figure of merit, ranging from 0.01 up to 1.6 at room temperature, may be expected for these systems. We compare our results with available experimental data on transport properties of QCs and suggest some potential candidates for thermoelectric applications.

  18. The Evaluation of Bivariate Mixed Models in Meta-analyses of Diagnostic Accuracy Studies with SAS, Stata and R.

    PubMed

    Vogelgesang, Felicitas; Schlattmann, Peter; Dewey, Marc

    2018-05-01

    Meta-analyses require a thoroughly planned procedure to obtain unbiased overall estimates. From a statistical point of view not only model selection but also model implementation in the software affects the results. The present simulation study investigates the accuracy of different implementations of general and generalized bivariate mixed models in SAS (using proc mixed, proc glimmix and proc nlmixed), Stata (using gllamm, xtmelogit and midas) and R (using reitsma from package mada and glmer from package lme4). Both models incorporate the relationship between sensitivity and specificity - the two outcomes of interest in meta-analyses of diagnostic accuracy studies - utilizing random effects. Model performance is compared in nine meta-analytic scenarios reflecting the combination of three sizes for meta-analyses (89, 30 and 10 studies) with three pairs of sensitivity/specificity values (97%/87%; 85%/75%; 90%/93%). The evaluation of accuracy in terms of bias, standard error and mean squared error reveals that all implementations of the generalized bivariate model calculate sensitivity and specificity estimates with deviations less than two percentage points. proc mixed which together with reitsma implements the general bivariate mixed model proposed by Reitsma rather shows convergence problems. The random effect parameters are in general underestimated. This study shows that flexibility and simplicity of model specification together with convergence robustness should influence implementation recommendations, as the accuracy in terms of bias was acceptable in all implementations using the generalized approach. Schattauer GmbH.

  19. FlaA proteins in Leptospira interrogans are essential for motility and virulence but are not required for formation of the flagellum sheath.

    PubMed

    Lambert, Ambroise; Picardeau, Mathieu; Haake, David A; Sermswan, Rasana W; Srikram, Amporn; Adler, Ben; Murray, Gerald A

    2012-06-01

    Spirochetes have periplasmic flagella composed of a core surrounded by a sheath. The pathogen Leptospira interrogans has four flaB (proposed core subunit) and two flaA (proposed sheath subunit) genes. The flaA genes are organized in a locus with flaA2 immediately upstream of flaA1. In this study, flaA1 and flaA2 mutants were constructed by transposon mutagenesis. Both mutants still produced periplasmic flagella. The flaA1 mutant did not produce FlaA1 but continued to produce FlaA2 and retained normal morphology and virulence in a hamster model of infection but had reduced motility. The flaA2 mutant did not produce either the FlaA1 or the FlaA2 protein. Cells of the flaA2 mutant lacked the distinctive hook-shaped ends associated with L. interrogans and lacked translational motility in liquid and semisolid media. These observations were confirmed with a second, independent flaA2 mutant. The flaA2 mutant failed to cause disease in animal models of acute infection. Despite lacking FlaA proteins, the flagella of the flaA2 mutant were of the same thickness as wild-type flagella, as measured by electron microscopy, and exhibited a normal flagellum sheath, indicating that FlaA proteins are not essential for the synthesis of the flagellum sheath, as observed for other spirochetes. This study shows that FlaA subunits contribute to leptospiral translational motility, cellular shape, and virulence.

  20. University of Glasgow at TREC 2014: Experiments with Terrier in Contextual Suggestion, Temporal Summarisation and Web Tracks

    DTIC Science & Technology

    2014-11-01

    Romain Deveaud, M-Dyaa Albakour, Stuart Mackie, Nut Limsopatham, Craig Macdonald, Iadh Ounis, Thibaut Thonet ⇤ and Bekir Taner Dinçer † {firstname.lastname...of Tor Vergata at TREC 2007 Blog track. In Proc. of TREC, 2007. [3] J . Aslam, M. Ekstrand-Abueg, V. Pavlu, F. Diaz, and T. Sakai. Trec 2013 temporal...selection based on prevalence and novelty. In Proc. of CIKM’14, 2014. [18] R. McCreadie, C. Macdonald, I. Ounis, J . Peng, and R. L. T. Santos. University of

  1. Military Application of Space-Time Adaptive Processing (Les applications militaires du traitement adaptatif espace-temps)

    DTIC Science & Technology

    2003-04-01

    La détection de cibles mobiles terrestres est l’un des objectifs primaires de la télédétection depuis la terre. Cependant, les retours de cible...Proc. EUSAR’96, 26-28 March 1996, Koenigswinter, Germany, pp. 49-52 ( VDE Publishers) [13] Ender, J., ”Detection and Estimation of Moving Target...Signals by Multi-Channel SAR”, Proc. EUSAR’96, 26-28 March 1996, Koenigswinter, Germany, pp. 411-417, ( VDE Publishers). Also: AEU, Vol. 50, March 1996, pp

  2. Implementation of a Localization System for Sensor Networks

    DTIC Science & Technology

    2006-05-18

    its N-point DFT is mathematically formulated as X[k] = N−1∑ n=0 x[n] W nkN , k = 0, 1, . . . , N − 1 (7.1) W knN = e −j(2π/N)kn (7.2) There are two...distributed ad-hoc wireless sensor networks. In Int. Conf. on Acoustics, Speech , and Signal Proc. (ICASSP), pages 2037 – 2040, Salt Lake City, UT. [18] J...Stability of recursive qrd-ls algorithms using finite- precision systolic array implementation. IEEE Trans. on Acoustics, Speech , and Signal Proc., 37(5

  3. KENNEDY SPACE CENTER, FLA. - From left, Bob McLean, Southwest Texas State University; Valerie Cassanto, Instrumentation Technology Associates, Inc.; and Dennis Morrison, NASA Johnson Space Center, process one of the experiments carried on mission STS-107. Several experiments were found during the search for Columbia debris. Included in the Commercial ITA Biomedical Experiments payload on mission STS-107 are urokinase cancer research, microencapsulation of drugs, the Growth of Bacterial Biofilm on Surfaces during Spaceflight (GOBBSS), and tin crystal formation.

    NASA Image and Video Library

    2003-05-07

    KENNEDY SPACE CENTER, FLA. - From left, Bob McLean, Southwest Texas State University; Valerie Cassanto, Instrumentation Technology Associates, Inc.; and Dennis Morrison, NASA Johnson Space Center, process one of the experiments carried on mission STS-107. Several experiments were found during the search for Columbia debris. Included in the Commercial ITA Biomedical Experiments payload on mission STS-107 are urokinase cancer research, microencapsulation of drugs, the Growth of Bacterial Biofilm on Surfaces during Spaceflight (GOBBSS), and tin crystal formation.

  4. KENNEDY SPACE CENTER, FLA. - Valerie Cassanto, with Instrumentation Technology Associates, Inc., and Bob McLean, from the Southwest Texas State University, transfer to a new container material from one of the experiments carried on mission STS-107. Several experiments were found during the search for Columbia debris. Included in the Commercial ITA Biomedical Experiments payload on mission STS-107 are urokinase cancer research, microencapsulation of drugs, the Growth of Bacterial Biofilm on Surfaces during Spaceflight (GOBBSS), and tin crystal formation.

    NASA Image and Video Library

    2003-05-06

    KENNEDY SPACE CENTER, FLA. - Valerie Cassanto, with Instrumentation Technology Associates, Inc., and Bob McLean, from the Southwest Texas State University, transfer to a new container material from one of the experiments carried on mission STS-107. Several experiments were found during the search for Columbia debris. Included in the Commercial ITA Biomedical Experiments payload on mission STS-107 are urokinase cancer research, microencapsulation of drugs, the Growth of Bacterial Biofilm on Surfaces during Spaceflight (GOBBSS), and tin crystal formation.

  5. KSC-2012-4408

    NASA Image and Video Library

    2012-08-14

    CAPE CANAVERAL, Fla. -- Florida's Lt. Gov. Jennifer Carroll talks about the positive impact the aerospace industry has on the state of Florida during the National Space Club Florida Committee's August luncheon at the Radisson Resort at the Port in Cape Canaveral, Fla. NASA Commercial Crew Program Manager Ed Mango also discussed the innovative steps the agency is taking with industry partners to develop the next U.S. space transportation capability to and from low Earth orbit, which will eventually be available for use by the U.S. government and other commercial customers. To learn more about the Commercial Crew Program, visit www.nasa.gov/commercialcrew. Photo credit: Kim Shiflett

  6. KSC-2012-4409

    NASA Image and Video Library

    2012-08-14

    CAPE CANAVERAL, Fla. -- Florida's Lt. Gov. Jennifer Carroll talks about the positive impact the aerospace industry has on the state of Florida during the National Space Club Florida Committee's August luncheon at the Radisson Resort at the Port in Cape Canaveral, Fla. NASA Commercial Crew Program Manager Ed Mango also discussed the innovative steps the agency is taking with industry partners to develop the next U.S. space transportation capability to and from low Earth orbit, which will eventually be available for use by the U.S. government and other commercial customers. To learn more about the Commercial Crew Program, visit www.nasa.gov/commercialcrew. Photo credit: Kim Shiflett

  7. KSC-2012-4410

    NASA Image and Video Library

    2012-08-14

    CAPE CANAVERAL, Fla. -- Florida's Lt. Gov. Jennifer Carroll talks about the positive impact the aerospace industry has on the state of Florida during the National Space Club Florida Committee's August luncheon at the Radisson Resort at the Port in Cape Canaveral, Fla. NASA Commercial Crew Program Manager Ed Mango also discussed the innovative steps the agency is taking with industry partners to develop the next U.S. space transportation capability to and from low Earth orbit, which will eventually be available for use by the U.S. government and other commercial customers. To learn more about the Commercial Crew Program, visit www.nasa.gov/commercialcrew. Photo credit: Kim Shiflett

  8. Deformation and stability of surface states in Dirac semimetals

    NASA Astrophysics Data System (ADS)

    Kargarian, Mehdi; Lu, Yuan-Ming; Randeria, Mohit

    2018-04-01

    The unusual surface states of topological semimetals have attracted a lot of attention. Recently, we showed [Proc. Natl. Acad. Sci. USA 113, 8648 (2016), 10.1073/pnas.1524787113] that for a Dirac semimetal (DSM) arising from band inversion, such as Na3Bi and Cd3As2 , the expected double Fermi arcs on the surface are not topologically protected. Quite generally, the arcs deform into states similar to those on the surface of a strong topological insulator. Here we address two questions related to deformation and stability of surface states in DSMs. First, we discuss why certain perturbations, no matter how large, are unable to destroy the double Fermi arcs. We show that this is related to a certain extra (particle-hole) symmetry, which is nongeneric in materials. Second, we discuss situations in which the surface states are completely destroyed without breaking any symmetry or impacting the bulk Dirac nodes. We are not aware of any experimental or density functional theory (DFT) candidates for a material which is a bulk DSM without any surface states, but our results clearly show that this is possible.

  9. The kinetic equations for rotating and gravitating spheroidal body

    NASA Astrophysics Data System (ADS)

    Krot, A.

    2003-04-01

    In papers [1],[2] it has been proposed a statistical model of the gravitational interaction of particles.In the framework of this model bodies have fuzzy outlines and are represented by means of spheroidal forms. A con- sistency of the proposed statistical model the Einstein general relativity [3], [4], [5] has been shown. In work [6], which is a continuation of the paper[2], it has been investigated a slowly evolving in time process of a gravitational compression of a spheroidal body close to an unstable equilibrium state. In the paper [7] the equation of motion of particles inside the weakly gravitating spheroidal body modeled by means of an ideal liquid has been obtained. It has been derived the equations of hyperbolic type for the gravitational field of a weakly gravitating spheroidal body under observable values of velocities of particles composing it [7],[8]. This paper considers the case of gravitational compres- sion of spheroidal body with observable values of parti- cles.This means that distribution function of particles inside weakly rotating spheroidal body is a sum of an isotropic space-homogeneous stationary distribution function and its change (disturbance) under influence of dymanical gravitational field. The change of initial space-homogeneous stationary distribution function satisfyes the Boltzmann kinetic equation. This paper shows that if gravitating spheroidal body is rotating uniformly or is being at rest then distribution function of its particles satisfyes the Liouville theorem. Thus, being in unstable statistical quasiequilibrium the gravi- tating spheroidal body is rotating with constant angular velocity (or, in particular case, is being at rest). The joint distribution function of spheroidal body's particles in to coordinate space and angular velocity space is introduced. References [1] A.M.Krot, Achievements in Modern Radioelectronics, special issue "Cosmic Radiophysics",no. 8, pp.66-81, 1996 (Moscow, Russia). [2] A.M.Krot, Proc. SPIE 13th Symp."AeroSense", Orlando, Florida,USA, 5-9 April,vol. 3710, pp.1242-1259,1999. [3] L.D.Landau and E.M.Lifshitz, Classical Theory of Fields, Addison-Wesley, 1951. [4] S.Weinberg, Gravitation and Cosmology, John Wiley and Sons: New York, 1972. [5] C.W.Misner, K.S.Thorne,and J.A.Wheeler, Gravitation, W.H.Freeman and Co., San Francisco, 1973. [6] A.M.Krot, Proc. SPIE 14th Symp. "AeroSense",Orlando, Florida, USA, 24-29 April,vol.4038,pp.1318-1329,2000. [7] A.M.Krot, Proc. SPIE 15th Symp. "AeroSense",Orlando, Florida, USA, 16-20 April,vol.4394,pp.1217-1282,2001. [8] A.M.Krot, Proc. 53rd Intern. Astronautical Congress, The World Space Congress-2002, Houston, Texas, USA, 10-19 October,Preprint IAC-02-J.p.1,pp.1-11,2002.

  10. Delay Differential Equation-Based Modeling of Passively Mode-Locked Quantum Dot Lasers Using Measured Gain and Loss Spectra (Postprint)

    DTIC Science & Technology

    2013-01-01

    semiconductor laser8, 9: ATAe d dA TQiTGi qg 12 11 2 1 (1) 2 0 1 AeeGgd dG GQ (2) Proc. of SPIE Vol. 8255 82551K-2 Downloaded From: http...1 Downloaded From: http://spiedigitallibrary.org/ on 01/14/2013 Terms of Use: http://spiedl.org/terms 1 Approved for public release; distribution...parameters ( 0g and 0q , respectively) have been derived to yield: Gg0 (10) Proc. of SPIE Vol. 8255 82551K-3 Downloaded From: http

  11. Security of two-state and four-state practical quantum bit-commitment protocols

    NASA Astrophysics Data System (ADS)

    Loura, Ricardo; Arsenović, Dušan; Paunković, Nikola; Popović, Duška B.; Prvanović, Slobodan

    2016-12-01

    We study cheating strategies against a practical four-state quantum bit-commitment protocol [A. Danan and L. Vaidman, Quant. Info. Proc. 11, 769 (2012)], 10.1007/s11128-011-0284-4 and its two-state variant [R. Loura et al., Phys. Rev. A 89, 052336 (2014)], 10.1103/PhysRevA.89.052336 when the underlying quantum channels are noisy and the cheating party is constrained to using single-qubit measurements only. We show that simply inferring the transmitted photons' states by using the Breidbart basis, optimal for ambiguous (minimum-error) state discrimination, does not directly produce an optimal cheating strategy for this bit-commitment protocol. We introduce a strategy, based on certain postmeasurement processes and show it to have better chances at cheating than the direct approach. We also study to what extent sending forged geographical coordinates helps a dishonest party in breaking the binding security requirement. Finally, we investigate the impact of imperfect single-photon sources in the protocols. Our study shows that, in terms of the resources used, the four-state protocol is advantageous over the two-state version. The analysis performed can be straightforwardly generalized to any finite-qubit measurement, with the same qualitative results.

  12. Evaluation of canine red blood cell quality after processing with an automated cell salvage device.

    PubMed

    Hofbauer, Nina; Windberger, Ursula; Schwendenwein, Ilse; Tichy, Alexander; Eberspächer, Eva

    2016-05-01

    To evaluate the properties of RBC concentrate harvested after processing fresh whole blood units from healthy dogs with an automated cell salvage device. Prospective, in vitro, experimental study. University teaching hospital. Sixteen healthy, privately owned dogs of various breeds. Fresh canine whole blood collected in bags with citrate phosphate dextrose adenine solution was processed with an automated cell salvage device and analyzed in vitro. Laboratory values determined before (baseline, from a catheter sample) and after processing RBCs (procRBCs) included a complete blood count, selected blood chemistry analytes, erythrocyte osmotic resistance, whole blood viscosity, RBC aggregation, and RBC deformability. Total recovery of RBCs was 80% ± 12%. Hematocrit of the procRBCs yielded by the device was 77% ± 3.7% (mean ± standard deviation). Gross morphology of the RBCs remained unchanged. The mean corpuscular volume, erythrocyte osmotic resistance, RBC deformability, RBC aggregation, and the activity of lactate dehydrogenase showed minor but statistically significant changes from baseline. No differences in the concentrations of free hemoglobin were observed. Whole blood viscosity was less in the procRBCs. Seventy-seven percent (mean) of the platelets were washed out, while a mean of 57% of the leukocytes remained in the procRBCs. Although processing canine blood with this automated cell salvage device leads to slight changes in some properties of RBCs, most of these changes are comparable to changes seen in human blood after processing. Present data indicate that the use of this cell salvage device does not induce changes in canine RBC concentrate that would preclude its use for transfusion. © Veterinary Emergency and Critical Care Society 2016.

  13. KSC-04pd1893

    NASA Image and Video Library

    2004-09-22

    KENNEDY SPACE CENTER, FLA. - Large pieces of equipment in the Processing Control Center are covered in plastic in preparation for the arrival of Hurricane Jeanne, expected to impact Central Florida Sunday. This is the fourth hurricane in 45 days to make landfall somewhere in the state.

  14. Genetic Diversity of the Flagellin Genes of Clostridium botulinum Groups I and II

    PubMed Central

    Woudstra, Cedric; Lambert, Dominic; Anniballi, Fabrizio; De Medici, Dario; Austin, John

    2013-01-01

    Botulinum neurotoxins (BoNTs) are produced by phenotypically and genetically different Clostridium species, including Clostridium botulinum and some strains of Clostridium baratii (serotype F) and Clostridium butyricum (serotype E). BoNT-producing clostridia responsible for human botulism encompass strains of group I (secreting proteases, producing toxin serotype A, B, or F, and growing optimally at 37°C) and group II (nonproteolytic, producing toxin serotype E, B, or F, and growing optimally at 30°C). Here we report the development of real-time PCR assays for genotyping C. botulinum strains of groups I and II based on flaVR (variable region sequence of flaA) sequences and the flaB gene. Real-time PCR typing of regions flaVR1 to flaVR10 and flaB was optimized and validated with 62 historical and Canadian C. botulinum strains that had been previously typed. Analysis of 210 isolates of European origin allowed the identification of four new C. botulinum flaVR types (flaVR11 to flaVR14) and one new flaVR type specific to C. butyricum type E (flaVR15). The genetic diversity of the flaVR among C. botulinum strains investigated in the present study reveals the clustering of flaVR types into 5 major subgroups. Subgroups 1, 3, and 4 contain proteolytic Clostridium botulinum, subgroup 2 is made up of nonproteolytic C. botulinum only, and subgroup 5 is specific to C. butyricum type E. The genetic variability of the flagellin genes carried by C. botulinum and the possible association of flaVR types with certain geographical areas make gene profiling of flaVR and flaB promising in molecular surveillance and epidemiology of C. botulinum. PMID:23603687

  15. Structural Characterization of the Fla2 Flagellum of Rhodobacter sphaeroides

    PubMed Central

    de la Mora, Javier; Uchida, Kaoru; del Campo, Ana Martínez; Camarena, Laura; Aizawa, Shin-Ichi

    2015-01-01

    ABSTRACT Rhodobacter sphaeroides is a free-living alphaproteobacterium that contains two clusters of functional flagellar genes in its genome: one acquired by horizontal gene transfer (fla1) and one that is endogenous (fla2). We have shown that the Fla2 system is normally quiescent and under certain conditions produces polar flagella, while the Fla1 system is always active and produces a single flagellum at a nonpolar position. In this work we purified and characterized the structure and analyzed the composition of the Fla2 flagellum. The number of polar filaments per cell is 4.6 on average. By comparison with the Fla1 flagellum, the prominent features of the ultra structure of the Fla2 HBB are the absence of an H ring, thick and long hooks, and a smoother zone at the hook-filament junction. The Fla2 helical filaments have a pitch of 2.64 μm and a diameter of 1.4 μm, which are smaller than those of the Fla1 filaments. Fla2 filaments undergo polymorphic transitions in vitro and showed two polymorphs: curly (right-handed) and coiled. However, in vivo in free-swimming cells, we observed only a bundle of filaments, which should probably be left-handed. Together, our results indicate that Fla2 cell produces multiple right-handed polar flagella, which are not conventional but exceptional. IMPORTANCE R. sphaeroides possesses two functional sets of flagellar genes. The fla1 genes are normally expressed in the laboratory and were acquired by horizontal transfer. The fla2 genes are endogenous and are expressed in a Fla1− mutant grown phototrophically and in the absence of organic acids. The Fla1 system produces a single lateral or subpolar flagellum, and the Fla2 system produces multiple polar flagella. The two kinds of flagella are never expressed simultaneously, and both are used for swimming in liquid media. The two sets of genes are certainly ready for responding to specific environmental conditions. The characterization of the Fla2 system will help us to understand its role in the physiology of this microorganism. PMID:26124240

  16. Utilization Management of Orthopedic Services by Fitzsimons Army Medical Center and Evans Army Community Hospital

    DTIC Science & Technology

    1993-08-01

    LOS Mean LOS: Total LOS: positions g FAMC-HCFA FAMC-HCFA 214 Back & Neck Proc with CC 5 4.02 51.6 42.6 213 2_11 Wound Debrid & Skin Graft ex Hand, for...Administration (HCFA) DRG Dis- CMI FAMC LO5 Mean LOS: Total LOS: posit’i Mean FAMC-HCFA FAMC-HCFA 263 Skin Graft &/ox Debrid for Skin Ulcer or Cellulitis w CC...32.0 21.4 43 468 Extensive O.R. Proc Un- Related to Principal DX 16 3.42 7.6 -5.5 -89 217 Wound Debrid & Skin Graft ex Hand, for Muscskelet & Conn

  17. No regularity singularities exist at points of general relativistic shock wave interaction between shocks from different characteristic families.

    PubMed

    Reintjes, Moritz; Temple, Blake

    2015-05-08

    We give a constructive proof that coordinate transformations exist which raise the regularity of the gravitational metric tensor from C 0,1 to C 1,1 in a neighbourhood of points of shock wave collision in general relativity. The proof applies to collisions between shock waves coming from different characteristic families, in spherically symmetric spacetimes. Our result here implies that spacetime is locally inertial and corrects an error in our earlier Proc. R. Soc. A publication, which led us to the false conclusion that such coordinate transformations, which smooth the metric to C 1,1 , cannot exist. Thus, our result implies that regularity singularities (a type of mild singularity introduced in our Proc. R. Soc. A paper) do not exist at points of interacting shock waves from different families in spherically symmetric spacetimes. Our result generalizes Israel's celebrated 1966 paper to the case of such shock wave interactions but our proof strategy differs fundamentally from that used by Israel and is an extension of the strategy outlined in our original Proc. R. Soc. A publication. Whether regularity singularities exist in more complicated shock wave solutions of the Einstein-Euler equations remains open.

  18. No regularity singularities exist at points of general relativistic shock wave interaction between shocks from different characteristic families

    PubMed Central

    Reintjes, Moritz; Temple, Blake

    2015-01-01

    We give a constructive proof that coordinate transformations exist which raise the regularity of the gravitational metric tensor from C0,1 to C1,1 in a neighbourhood of points of shock wave collision in general relativity. The proof applies to collisions between shock waves coming from different characteristic families, in spherically symmetric spacetimes. Our result here implies that spacetime is locally inertial and corrects an error in our earlier Proc. R. Soc. A publication, which led us to the false conclusion that such coordinate transformations, which smooth the metric to C1,1, cannot exist. Thus, our result implies that regularity singularities (a type of mild singularity introduced in our Proc. R. Soc. A paper) do not exist at points of interacting shock waves from different families in spherically symmetric spacetimes. Our result generalizes Israel's celebrated 1966 paper to the case of such shock wave interactions but our proof strategy differs fundamentally from that used by Israel and is an extension of the strategy outlined in our original Proc. R. Soc. A publication. Whether regularity singularities exist in more complicated shock wave solutions of the Einstein–Euler equations remains open. PMID:27547092

  19. KSC-04pd1891

    NASA Image and Video Library

    2004-09-22

    KENNEDY SPACE CENTER, FLA. - Workers place plastic sheets over racks of equipment in the Reusable Launch Vehicle Support Complex in preparation for the arrival of Hurricane Jeanne, expected to impact Central Florida Sunday. This is the fourth hurricane in 45 days to make landfall somewhere in the state.

  20. KSC-04pd1892

    NASA Image and Video Library

    2004-09-22

    KENNEDY SPACE CENTER, FLA. - Workers place plastic sheets over racks of equipment in the Reusable Launch Vehicle Support Complex in preparation for the arrival of Hurricane Jeanne, expected to impact Central Florida Sunday. This is the fourth hurricane in 45 days to make landfall somewhere in the state.

  1. KENNEDY SPACE CENTER, FLA. - Barry Perlman, Pembroke Pines Charter Middle School in Florida, examines one of the experiments carried on mission STS-107 as Bob McLean, Southwest Texas State University, looks on. Several experiments were found during the search for Columbia debris. Included in the Commercial ITA Biomedical Experiments payload on mission STS-107 are urokinase cancer research, microencapsulation of drugs, the Growth of Bacterial Biofilm on Surfaces during Spaceflight (GOBBSS), and tin crystal formation. The latter was sponsored by the Pembroke Pines Charter Middle School.

    NASA Image and Video Library

    2003-05-07

    KENNEDY SPACE CENTER, FLA. - Barry Perlman, Pembroke Pines Charter Middle School in Florida, examines one of the experiments carried on mission STS-107 as Bob McLean, Southwest Texas State University, looks on. Several experiments were found during the search for Columbia debris. Included in the Commercial ITA Biomedical Experiments payload on mission STS-107 are urokinase cancer research, microencapsulation of drugs, the Growth of Bacterial Biofilm on Surfaces during Spaceflight (GOBBSS), and tin crystal formation. The latter was sponsored by the Pembroke Pines Charter Middle School.

  2. KENNEDY SPACE CENTER, FLA. - NASA Vehicle Manager for Discovery, Stephanie Stilson poses for a photo after working with a KSC Web team who were filming a special feature for the KSC Web. Stilson explained her role in the recent Orbiter Major Modification period, which included inspection, modifications and reservicing of most systems onboard. The work on Discovery also included the installation of a Multifunction Electronic Display Subsystem (MEDS) - a state-of-the-art “glass cockpit.” The orbiter is now being prepared for eventual launch on a future mission.

    NASA Image and Video Library

    2004-01-22

    KENNEDY SPACE CENTER, FLA. - NASA Vehicle Manager for Discovery, Stephanie Stilson poses for a photo after working with a KSC Web team who were filming a special feature for the KSC Web. Stilson explained her role in the recent Orbiter Major Modification period, which included inspection, modifications and reservicing of most systems onboard. The work on Discovery also included the installation of a Multifunction Electronic Display Subsystem (MEDS) - a state-of-the-art “glass cockpit.” The orbiter is now being prepared for eventual launch on a future mission.

  3. KENNEDY SPACE CENTER, FLA. - Standing on a workstand (at left) in the Orbiter Processing Facility is Stephanie Stilson, NASA vehicle manager for Discovery. She is being filmed for a special feature on the KSC Web about the recent Orbiter Major Modification period on Discovery, which included inspection, modifications and reservicing of most systems onboard, plus installation of a Multifunction Electronic Display Subsystem (MEDS) - a state-of-the-art “glass cockpit.” The orbiter is now being prepared for eventual launch on a future mission.

    NASA Image and Video Library

    2004-01-22

    KENNEDY SPACE CENTER, FLA. - Standing on a workstand (at left) in the Orbiter Processing Facility is Stephanie Stilson, NASA vehicle manager for Discovery. She is being filmed for a special feature on the KSC Web about the recent Orbiter Major Modification period on Discovery, which included inspection, modifications and reservicing of most systems onboard, plus installation of a Multifunction Electronic Display Subsystem (MEDS) - a state-of-the-art “glass cockpit.” The orbiter is now being prepared for eventual launch on a future mission.

  4. KENNEDY SPACE CENTER, FLA. - In the Orbiter Processing Facility, Stephanie Stilson, NASA vehicle manager for Discovery, stands in front of a leading edge on the wing of Discovery. She is being filmed for a special feature on the KSC Web about the recent Orbiter Major Modification period on Discovery, which included inspection, modifications and reservicing of most systems onboard, plus installation of a Multifunction Electronic Display Subsystem (MEDS) - a state-of-the-art “glass cockpit.” The orbiter is now being prepared for eventual launch on a future mission.

    NASA Image and Video Library

    2004-01-22

    KENNEDY SPACE CENTER, FLA. - In the Orbiter Processing Facility, Stephanie Stilson, NASA vehicle manager for Discovery, stands in front of a leading edge on the wing of Discovery. She is being filmed for a special feature on the KSC Web about the recent Orbiter Major Modification period on Discovery, which included inspection, modifications and reservicing of most systems onboard, plus installation of a Multifunction Electronic Display Subsystem (MEDS) - a state-of-the-art “glass cockpit.” The orbiter is now being prepared for eventual launch on a future mission.

  5. KENNEDY SPACE CENTER, FLA. - During power-up of the orbiter Discovery in the Orbiter Processing Facility, a technician moves a switch. Discovery has been undergoing Orbiter Major Modifications in the past year, ranging from wiring, control panels and black boxes to gaseous and fluid systems tubing and components. These systems were deserviced, disassembled, inspected, modified, reassembled, checked out and reserviced, as were most other systems onboard. The work includes the installation of the Multifunction Electronic Display Subsystem (MEDS) - a state-of-the-art “glass cockpit.”

    NASA Image and Video Library

    2003-08-27

    KENNEDY SPACE CENTER, FLA. - During power-up of the orbiter Discovery in the Orbiter Processing Facility, a technician moves a switch. Discovery has been undergoing Orbiter Major Modifications in the past year, ranging from wiring, control panels and black boxes to gaseous and fluid systems tubing and components. These systems were deserviced, disassembled, inspected, modified, reassembled, checked out and reserviced, as were most other systems onboard. The work includes the installation of the Multifunction Electronic Display Subsystem (MEDS) - a state-of-the-art “glass cockpit.”

  6. KENNEDY SPACE CENTER, FLA. - During power-up of the orbiter Discovery in the Orbiter Processing Facility, a technician turns on a switch. Discovery has been undergoing Orbiter Major Modifications in the past year, ranging from wiring, control panels and black boxes to gaseous and fluid systems tubing and components. These systems were deserviced, disassembled, inspected, modified, reassembled, checked out and reserviced, as were most other systems onboard. The work includes the installation of the Multifunction Electronic Display Subsystem (MEDS) - a state-of-the-art “glass cockpit.”

    NASA Image and Video Library

    2003-08-27

    KENNEDY SPACE CENTER, FLA. - During power-up of the orbiter Discovery in the Orbiter Processing Facility, a technician turns on a switch. Discovery has been undergoing Orbiter Major Modifications in the past year, ranging from wiring, control panels and black boxes to gaseous and fluid systems tubing and components. These systems were deserviced, disassembled, inspected, modified, reassembled, checked out and reserviced, as were most other systems onboard. The work includes the installation of the Multifunction Electronic Display Subsystem (MEDS) - a state-of-the-art “glass cockpit.”

  7. Identification of a second flagellin gene and functional characterization of a sigma70-like promoter upstream of a Leptospira borgpetersenii flaB gene.

    PubMed

    Lin, Min; Dan, Hanhong; Li, Yijing

    2004-02-01

    Leptospira borgpetersenii, one of the causative agents of leptospirosis in both animals and humans, is a bacterial pathogen with characteristic motility that is mediated by the rotation of two periplasmic flagella (PF). The flaB gene coding for a core polypeptide subunit of PF was previously characterized by sequence analysis of its open reading frame (ORF) (M. Lin, J Biochem Mol Biol Biophys 2:181-187, 1999). The present study was undertaken to isolate and clone the uncharacterized sequence upstream of the flaB gene by using a PCR-based genome walking procedure. This has resulted in a 1470-bp genomic DNA sequence in which an 846-bp ORF coding for a 281-amino acid polypeptide (31.3 kDa) is identified 455 bp upstream from the flaB start codon. The encoded protein exhibits 72% amino acid identity to the deduced FlaB protein sequence of L. borgpetersenii and a high degree of sequence homology to the FlaB proteins of other spirochaetes. This has demonstrated for the first time that a second flaB gene homolog is present in a Leptospira species. The newly identified gene is designated flaB1, and the previously cloned flaB renamed flaB2. Within the intergenic sequence between flaB1 and flaB2, a potential stem-loop structure (12-bp inverted repeats) was identified 25 bp downstream of the flaB1 stop codon; this could serve as a transcription terminator for the flaB1 mRNA. Three E. coli-like promoter regions (I, II, and III) for binding Esigma(70), a regulatory sequence uncommonly found in flagellar genes, were predicted upstream of the flaB2 ORF. Only promoter region II contains a promoter that is functional in E. coli, as revealed at phenotypic and transcriptional levels by its capability of directing the expression of the chloramphenicol acetyltransferase (CAT) gene in the promoter probe vector pKK232-8. These observations may suggest that flaB1 and flaB2 are transcribed separately and do not form a transcriptional operon controlled by a single promoter.

  8. KSC-04PD-1956

    NASA Technical Reports Server (NTRS)

    2004-01-01

    KENNEDY SPACE CENTER, FLA. An aerial view of the Vehicle Assembly Building at KSC shows damage to the roof inflicted by both Hurricane Frances and the category 3 Hurricane Jeanne. The latter storm barreled through Central Florida Sept. 25-26, the fourth hurricane in 6 weeks to batter the state.

  9. KSC-04pd1912

    NASA Image and Video Library

    2004-09-27

    KENNEDY SPACE CENTER, FLA. - - In the Orbiter Processing Facility, the wheel on Atlantis is covered in plastic that protected it from possible damage by Hurricane Jeanne. The storm barreled through Central Florida Sept. 25-26 from the southeast. This was the fourth hurricane in 6 weeks to batter the state.

  10. Elastic instabilities in rubber

    NASA Astrophysics Data System (ADS)

    Gent, Alan

    2009-03-01

    Materials that undergo large elastic deformations can exhibit novel instabilities. Several examples are described: development of an aneurysm on inflating a rubber tube; non-uniform stretching on inflating a spherical balloon; formation of internal cracks in rubber blocks at a critical level of triaxial tension or when supersaturated with a dissolved gas; surface wrinkling of a block at a critical amount of compression; debonding or fracture of constrained films on swelling, and formation of ``knots'' on twisting stretched cylindrical rods. These various deformations are analyzed in terms of a simple strain energy function, using Rivlin's theory of large elastic deformations, and the results are compared with experimental measurements of the onset of unstable states. Such comparisons provide new tests of Rivlin's theory and, at least in principle, critical tests of proposed strain energy functions for rubber. Moreover the onset of highly non-uniform deformations has serious implications for the fatigue life and fracture resistance of rubber components. [4pt] References: [0pt] R. S. Rivlin, Philos. Trans. Roy. Soc. Lond. Ser. A241 (1948) 379--397. [0pt] A. Mallock, Proc. Roy. Soc. Lond. 49 (1890--1891) 458--463. [0pt] M. A. Biot, ``Mechanics of Incremental Deformations'', Wiley, New York, 1965. [0pt] A. N. Gent and P. B. Lindley, Proc. Roy. Soc. Lond. A 249 (1958) 195--205. [0pt] A. N. Gent, W. J. Hung and M. F. Tse, Rubb. Chem. Technol. 74 (2001) 89--99. [0pt] A. N. Gent, Internatl. J. Non-Linear Mech. 40 (2005) 165--175.

  11. A link between torse-forming vector fields and rotational hypersurfaces

    NASA Astrophysics Data System (ADS)

    Chen, Bang-Yen; Verstraelen, Leopold

    Torse-forming vector fields introduced by Yano [On torse forming direction in a Riemannian space, Proc. Imp. Acad. Tokyo 20 (1944) 340-346] are natural extension of concurrent and concircular vector fields. Such vector fields have many nice applications to geometry and mathematical physics. In this paper, we establish a link between rotational hypersurfaces and torse-forming vector fields. More precisely, our main result states that, for a hypersurface M of 𝔼n+1 with n ≥ 3, the tangential component xT of the position vector field of M is a proper torse-forming vector field on M if and only if M is contained in a rotational hypersurface whose axis of rotation contains the origin.

  12. Optical characterization of antirelaxation coatings

    NASA Astrophysics Data System (ADS)

    Tsvetkov, S.; Gateva, S.; Cartaleva, S.; Mariotti, E.; Nasyrov, K.

    2018-03-01

    Antirelaxation coatings (ARC) are used in optical cells containing alkali metal vapor to reduce the depolarization of alkali atoms after collisions with the cell walls. The long-lived ground state polarization is a basis for development of atomic clocks, magnetometers, quantum memory, slow light experiments, precision measurements of fundamental symmetries etc. In this work, a simple method for measuring the number of collisions of the alkali atoms with the cell walls without atomic spin randomization (Nasyrov et al., Proc. SPIE (2015)) was applied to characterize the AR properties of two PDMS coatings prepared from different solutions in ether (PDMS 2% and PDMS 5%). We observed influence of the light-induced atomic desorption (LIAD) on the AR properties of coatings.

  13. Steady-State Operation in Tore Supra

    NASA Astrophysics Data System (ADS)

    Hoang, G. T.; Tore Supra, Equipe

    1999-11-01

    The Tore Supra superconducting tokamak is devoted to steady-state operation. The CIEL (French acronym for internal component and limiter) project( LIPA, M., et al., Proc. of the 17th IEEE/NPSS Symp. on Fus. Engineering, San Diego, USA, 1997.) consists of a complete upgrade of the inner chamber of Tore Supra, planned to be installed during the year 2000. This project will allow physics scenarios with up to 24 MW of radio frequency heating and current drive (typically 8 - 10 MW of ICRF, 10 - 12 MW of LHCD and 2 MW of ECRF) in stationary plasmas up to 1000 s, with active particle control. This paper presents an overview of the experiments planned to explore the properties, such as the confinement and MHD stability, of various heating and current drive scenarios for long duration discharges. The expected performance for the CIEL phase is also reported.

  14. Evaluation of FlaB1, FlaB2, FlaB3, and Tp0463 of Treponema pallidum for serodiagnosis of syphilis.

    PubMed

    Jiang, Chuanhao; Xiao, Jinhong; Xie, Yafeng; Xiao, Yongjian; Wang, Chuan; Kuang, Xingxing; Xu, Man; Li, Ranhui; Zeng, Tiebing; Liu, Shuanquan; Yu, Jian; Zhao, Feijun; Wu, Yimou

    2016-02-01

    Syphilis is a multistage disease caused by the invasive spirochete Treponema pallidum subsp. pallidum, and accurate diagnosis is important for the prevention and treatment of syphilis. Here, to identify appropriate diagnostic antigens for serodiagnosis of syphilis, 6 recombinant proteins were expressed in Escherichia coli and purified, including flagellins (FlaB1 [Tp0868], FlaB2 [Tp0792], and FlaB3 [Tp0870]), Tp0463, Tp0751, and Tp1038. The sensitivities were determined by screening sera from individuals with primary (n=82), secondary (n=115), latent (n=105), and congenital (n=65) syphilis. The specificities were determined by screening sera from uninfected controls (n=30) and potentially cross-reactive infections including Lyme disease (n=30), leptospirosis (n=5), and hepatitis B (n=30). Our data showed that FlaB1, FlaB2, FlaB3, Tp0463, and Tp1038 exhibited higher overall sensitivities and specificities for detecting IgG antibody, with 95.4% and 98.9%, 92.6% and 95.8%, 95.1% and 95.8%, 92.6% and 97.9%, and 95.9% and 98.9%, respectively. In contrast, Tp0751 demonstrated only an overall sensitivity of 39.2%. For comparison, the sensitivity and specificity of Architect Syphilis TP were determined to be 98.1% and 93.7%, respectively. In addition, FlaB1, FlaB2, FlaB3, and Tp0463 demonstrated excellent performance for detecting IgM antibody in primary and congenital syphilis, with sensitivities of 76.8% and 83.1%, 72.0% and 87.7%, 74.4% and 89.2%, and 64.6% and 75.3%, respectively. These results indicate that FlaB1, FlaB2, FlaB3, and Tp0463 could be as novel diagnostic candidates for serodiagnosis of syphilis. Copyright © 2016 Elsevier Inc. All rights reserved.

  15. Fla. Panel's Evolution Vote Hailed

    ERIC Educational Resources Information Center

    Cavanagh, Sean

    2008-01-01

    This article reports on how the compromise hammered out in Florida recently over the treatment of evolution in the state's science classrooms is winning praise from scientists and educators. The new science standards will refer to evolution as the "scientific theory of evolution." These changes will replace more-general language in the…

  16. KSC-98pc1769

    NASA Image and Video Library

    1998-12-03

    KENNEDY SPACE CENTER, FLA. -- U.S. Secretary of State Madeleine Albright talks with NASA Administrator Daniel Goldin (at left) in the VIP lounge at the Apollo/Saturn V Center while awaiting launch of Mission STS-88, the first U.S. launch for the International Space Station. Astronaut Michael Lopez-Alegria is looking on in background

  17. KSC-04pd1894

    NASA Image and Video Library

    2004-09-22

    KENNEDY SPACE CENTER, FLA. - Large pieces of equipment in the Processing Control Center in the Launch Complex 39 Area are covered in plastic in preparation for the arrival of Hurricane Jeanne, expected to impact Central Florida Sunday. This is the fourth hurricane in 45 days to make landfall somewhere in the state.

  18. 7 CFR 351.2 - Location of inspectors.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ..., Hoboken, N.J., Honolulu, Hawaii, Houston, Tex., Jacksonville, Fla., Jamaica, L.I., N.Y., Key West, Fla..., Calif., Savannah, Ga., Seattle, Wash., Tampa, Fla., Toledo, Ohio, Washington, DC, West Palm Beach, Fla...

  19. 7 CFR 351.2 - Location of inspectors.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ..., Hoboken, N.J., Honolulu, Hawaii, Houston, Tex., Jacksonville, Fla., Jamaica, L.I., N.Y., Key West, Fla..., Calif., Savannah, Ga., Seattle, Wash., Tampa, Fla., Toledo, Ohio, Washington, DC, West Palm Beach, Fla...

  20. 7 CFR 351.2 - Location of inspectors.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ..., Hoboken, N.J., Honolulu, Hawaii, Houston, Tex., Jacksonville, Fla., Jamaica, L.I., N.Y., Key West, Fla..., Calif., Savannah, Ga., Seattle, Wash., Tampa, Fla., Toledo, Ohio, Washington, DC, West Palm Beach, Fla...

  1. 7 CFR 351.2 - Location of inspectors.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ..., Hoboken, N.J., Honolulu, Hawaii, Houston, Tex., Jacksonville, Fla., Jamaica, L.I., N.Y., Key West, Fla..., Calif., Savannah, Ga., Seattle, Wash., Tampa, Fla., Toledo, Ohio, Washington, DC, West Palm Beach, Fla...

  2. Double-bosonization and Majid's conjecture, (I): Rank-inductions of ABCD

    NASA Astrophysics Data System (ADS)

    Hu, Hongmei; Hu, Naihong

    2015-11-01

    Majid developed in [S. Majid, Math. Proc. Cambridge Philos. Soc. 125, 151-192 (1999)] the double-bosonization theory to construct Uq(𝔤) and expected to generate inductively not just a line but a tree of quantum groups starting from a node. In this paper, the authors confirm Majid's first expectation (see p. 178 [S. Majid, Math. Proc. Cambridge Philos. Soc. 125, 151-192 (1999)]) through giving and verifying the full details of the inductive constructions of Uq(𝔤) for the classical types, i.e., the ABCD series. Some examples in low ranks are given to elucidate that any quantum group of classical type can be constructed from the node corresponding to Uq(𝔰𝔩2).

  3. 33 CFR 334.590 - Atlantic Ocean off Cape Canaveral, Fla.; Air Force missile testing area, Patrick Air Force Base...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ..., Fla.; Air Force missile testing area, Patrick Air Force Base, Fla. 334.590 Section 334.590 Navigation... RESTRICTED AREA REGULATIONS § 334.590 Atlantic Ocean off Cape Canaveral, Fla.; Air Force missile testing area, Patrick Air Force Base, Fla. (a) The danger zone. An area in the Atlantic Ocean immediately offshore from...

  4. Flagellin diversity in Clostridium botulinum groups I and II: a new strategy for strain identification.

    PubMed

    Paul, Catherine J; Twine, Susan M; Tam, Kevin J; Mullen, James A; Kelly, John F; Austin, John W; Logan, Susan M

    2007-05-01

    Strains of Clostridium botulinum are traditionally identified by botulinum neurotoxin type; however, identification of an additional target for typing would improve differentiation. Isolation of flagellar filaments and analysis by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) showed that C. botulinum produced multiple flagellin proteins. Nano-liquid chromatography-tandem mass spectrometry (nLC-MS/MS) analysis of in-gel tryptic digests identified peptides in all flagellin bands that matched two homologous tandem flagellin genes identified in the C. botulinum Hall A genome. Designated flaA1 and flaA2, these open reading frames encode the major structural flagellins of C. botulinum. Colony PCR and sequencing of flaA1/A2 variable regions classified 80 environmental and clinical strains into group I or group II and clustered isolates into 12 flagellar types. Flagellar type was distinct from neurotoxin type, and epidemiologically related isolates clustered together. Sequencing a larger PCR product, obtained during amplification of flaA1/A2 from type E strain Bennett identified a second flagellin gene, flaB. LC-MS analysis confirmed that flaB encoded a large type E-specific flagellin protein, and the predicted molecular mass for FlaB matched that observed by SDS-PAGE. In contrast, the molecular mass of FlaA was 2 to 12 kDa larger than the mass predicted by the flaA1/A2 sequence of a given strain, suggesting that FlaA is posttranslationally modified. While identification of FlaB, and the observation by SDS-PAGE of different masses of the FlaA proteins, showed the flagellin proteins of C. botulinum to be diverse, the presence of the flaA1/A2 gene in all strains examined facilitates single locus sequence typing of C. botulinum using the flagellin variable region.

  5. Sub-grid scale combustion models for large eddy simulation of unsteady premixed flame propagation around obstacles.

    PubMed

    Di Sarli, Valeria; Di Benedetto, Almerinda; Russo, Gennaro

    2010-08-15

    In this work, an assessment of different sub-grid scale (sgs) combustion models proposed for large eddy simulation (LES) of steady turbulent premixed combustion (Colin et al., Phys. Fluids 12 (2000) 1843-1863; Flohr and Pitsch, Proc. CTR Summer Program, 2000, pp. 61-82; Kim and Menon, Combust. Sci. Technol. 160 (2000) 119-150; Charlette et al., Combust. Flame 131 (2002) 159-180; Pitsch and Duchamp de Lageneste, Proc. Combust. Inst. 29 (2002) 2001-2008) was performed to identify the model that best predicts unsteady flame propagation in gas explosions. Numerical results were compared to the experimental data by Patel et al. (Proc. Combust. Inst. 29 (2002) 1849-1854) for premixed deflagrating flame in a vented chamber in the presence of three sequential obstacles. It is found that all sgs combustion models are able to reproduce qualitatively the experiment in terms of step of flame acceleration and deceleration around each obstacle, and shape of the propagating flame. Without adjusting any constants and parameters, the sgs model by Charlette et al. also provides satisfactory quantitative predictions for flame speed and pressure peak. Conversely, the sgs combustion models other than Charlette et al. give correct predictions only after an ad hoc tuning of constants and parameters. Copyright 2010 Elsevier B.V. All rights reserved.

  6. Light emitting diodes as a monitor to study P-type doping of GaN-based heterostructures grown by MOVPE

    NASA Astrophysics Data System (ADS)

    Schineller, B.; Guttzeit, A.; Vertommen, F.; Schön, O.; Heuken, M.; Heime, K.; Beccard, R.

    1998-06-01

    The group-III nitrides are an interesting material system for applications in the blue spectral region and for high-power and high-temperature devices. P-type doping in the metalorganic vapour-phase growth process, however, suffers from the material's high-background donor concentration. Hydrogen passivation furthermore decreases the number of activated acceptors [N.M. Johnson, W. Götz, J. Neugebauer, C.G. van de Walle, Mater. Res. Soc. Symp. Proc. 395 (1996) 723; A. Bosin, V. Fiorentini, Mater. Res. Soc. Symp. Proc. 395 (1996) 503] [1, 2]. Thermal treatment was found to increase the amount of activated acceptors [S.J. Pearton, S. Bendi, K.S. Jones, V. Krishnamoorthy, R.G. Wilson, F. Ren, R.F. Karlicek, R.A. Stall, Appl. Phys. Lett. 69 (1996) 1879; Y. Li, Y. Lu, H. Shen, M. Wraback, C.Y. Hwang, M. Schurman, W. Mayo, T. Salagaj, R.A. Stall, Mater. Res. Soc. Symp. Proc. 395 (1996) 369] [3, 4]. We have investigated the influences of thermal treatment process steps on the electrical and optical properties of Mg-doped single layers and used the results to fabricate AlGaN/GaN heterostructure LED layers. A simple test structure was employed to assess the electro-optical properties of the LED structures.

  7. Electromagnetic field effects in explosives

    NASA Astrophysics Data System (ADS)

    Tasker, Douglas

    2009-06-01

    Present and previous research on the effects of electromagnetic fields on the initiation and detonation of explosives and the electromagnetic properties of explosives are reviewed. Among the topics related to detonating explosives are: measurements of conductivity; enhancement of performance; and control of initiation and growth of reaction. Hayes...()^1 showed a strong correlation of peak electrical conductivity with carbon content of the detonation products. Ershov.......^2 linked detailed electrical conductivity measurements with reaction kinetics and this work was extended to enhance detonation performance electrically;...^3 for this, electrical power densities of the order of 100 TW/m^2 of explosive surface normal to the detonation front were required. However, small electrical powers are required to affect the initiation and growth of reaction.......^4,5 A continuation of this work will be reported. LA-UR 09-00873 .^1 B. Hayes, Procs. of 4th Symposium (International) on Detonation (1965), p. 595. ^2 A. Ershov, P. Zubkov, and L. Luk'yanchikov, Combustion, Explosion, and Shock Waves 10, 776-782 (1974). ^3 M. Cowperthwaite, Procs. 9th Detonation Symposium (1989), p. 388-395. ^4 M. A. Cook and T. Z. Gwyther, ``Influence of Electric Fields on Shock to Detonation Transition,'' (1965). ^5 D. Salisbury, R. Winter, and L. Biddle, Procs. of the APS Topical Conference on Shock Compression of Condensed Matter (2005) p. 1010-1013.

  8. Polymorphisms in antithrombin and in tissue factor pathway inhibitor genes are associated with recurrent pregnancy loss.

    PubMed

    Guerra-Shinohara, Elvira M; Bertinato, Juliano Felix; Tosin Bueno, Carolina; Cordeiro da Silva, Kelma; Burlacchini de Carvalho, Mário Henrique; Pulcineli Vieira Francisco, Rossana; Zugaib, Marcelo; Cerda, Alvaro; Morelli, Vânia Maris

    2012-10-01

    Recurrent pregnancy loss (RPL) is a multifactorial condition. The effect of antithrombin (SERPINC1), protein C (PROC), thrombomodulin (THBD) and tissue factor pathway inhibitor (TFPI) single nucleotide polymorphisms (SNPs) on the risk of RPL is thus far unknown. Our objective was to determine the association of SNPs in the above mentioned genes with RPL. We included 117 non-pregnant women with three or more consecutive losses prior to 20 weeks of pregnancy without a previous history of carrying a fetus to viability, and 264 healthy fertile non-pregnant women who had at least two term deliveries and no known pregnancy losses. The PROC (rs1799809 and rs1799808), SERPINC1 (rs2227589), THBD (rs1042579) and TFPI (rs10931292, rs8176592 and rs10153820) SNPs were analysed by Real Time PCR. Genotype frequencies for PROC 2418A>G, PROC 2405C>T, THBD 1418C>T, TFPI (T-33C and TFPI C-399T) SNPs were similar in cases and controls. The carriers of SERPINC1 786A allele (GA + AA genotypes) had an increased risk for RPL (odds ratio [OR]: 1.77, 95% confidence interval [CI]: 1.05-3.00, p= 0.034) while women carrying the TFPI -287C allele (TC + CC genotypes) had a protection effect on having RPL (OR: 0.46, 95% CI: 0.26-0.83, p= 0.009). The TCC haplotype for TFPI T-33C/ TFPI T-287C/ TFPI C-399T SNPs was less frequent in cases (5.7%) than in controls (11.6%) (OR: 0.45, 95% CI: 0.23-0.90, p= 0.025). In conclusion, our data indicate that SERPINC1 786G>A variant increases the risk for RPL, while TFPI T-287C variant is protective; however, further studies are required to confirm our findings.

  9. Low doses of allergen and probiotic supplementation separately or in combination alleviate allergic reactions to cow β-lactoglobulin in mice.

    PubMed

    Thang, Cin L; Boye, Joyce I; Zhao, Xin

    2013-02-01

    Probiotic supplementation and oral tolerance induction can reduce certain types of food allergy. The objectives of this study were to investigate the allergy-reducing effects of probiotics (VSL#3) and/or oral tolerance induction via low doses of an allergen supplementation in β-lactoglobulin (BLG)-sensitized mice. Three-week-old, male BALB/c mice were divided into 6 groups (n = 8/group): sham-sensitized negative control (CTL-), BLG-sensitized positive control (CTL+), oral tolerance-induced and BLG-sensitized group (OT), probiotic-supplemented OT group (OTP), probiotic-supplemented CTL- (PRO), and probiotic-supplemented and BLG-sensitized (PROC) groups. Mice were i.p. sensitized with BLG and alum and then orally challenged with BLG. Immunological responses were assessed by monitoring hypersensitivity scores and measuring levels of BLG-specific serum Igs, total serum IgE and fecal IgA, and cytokines from serum and spleen lysates. Hypersensitivity scores were significantly lower in the PROC (2.00 ± 0.53), OT (0.75 ± 0.46), and OTP mice (1.00 ± 0.53) than in the CTL+ mice (2.63 ± 0.52) as were BLG-specific serum IgE concentrations (34.3 ± 10, 0.442 ± 0.36, 3.54 ± 3.5, and 78.5 ± 8.7 μg/L for PROC, OT, OTP, and CTL+, respectively). Our results suggest that supplementation of VSL#3 suppressed the allergic reaction mainly through increased intestinal secretary IgA (sIgA) in PROC mice, and oral tolerance offered allergen-specific protective effects to BLG-induced allergy, probably through CD4+CD25+ regulatory T cell-mediated active suppression. In OTP mice, probiotics did not induce a further reduction of hypersensitivity score compared with OT mice but may provide additional protection to unforeseen nonspecific challenges through increased intestinal sIgA.

  10. Protein structure refinement using a quantum mechanics-based chemical shielding predictor.

    PubMed

    Bratholm, Lars A; Jensen, Jan H

    2017-03-01

    The accurate prediction of protein chemical shifts using a quantum mechanics (QM)-based method has been the subject of intense research for more than 20 years but so far empirical methods for chemical shift prediction have proven more accurate. In this paper we show that a QM-based predictor of a protein backbone and CB chemical shifts (ProCS15, PeerJ , 2016, 3, e1344) is of comparable accuracy to empirical chemical shift predictors after chemical shift-based structural refinement that removes small structural errors. We present a method by which quantum chemistry based predictions of isotropic chemical shielding values (ProCS15) can be used to refine protein structures using Markov Chain Monte Carlo (MCMC) simulations, relating the chemical shielding values to the experimental chemical shifts probabilistically. Two kinds of MCMC structural refinement simulations were performed using force field geometry optimized X-ray structures as starting points: simulated annealing of the starting structure and constant temperature MCMC simulation followed by simulated annealing of a representative ensemble structure. Annealing of the CHARMM structure changes the CA-RMSD by an average of 0.4 Å but lowers the chemical shift RMSD by 1.0 and 0.7 ppm for CA and N. Conformational averaging has a relatively small effect (0.1-0.2 ppm) on the overall agreement with carbon chemical shifts but lowers the error for nitrogen chemical shifts by 0.4 ppm. If an amino acid specific offset is included the ProCS15 predicted chemical shifts have RMSD values relative to experiments that are comparable to popular empirical chemical shift predictors. The annealed representative ensemble structures differ in CA-RMSD relative to the initial structures by an average of 2.0 Å, with >2.0 Å difference for six proteins. In four of the cases, the largest structural differences arise in structurally flexible regions of the protein as determined by NMR, and in the remaining two cases, the large structural change may be due to force field deficiencies. The overall accuracy of the empirical methods are slightly improved by annealing the CHARMM structure with ProCS15, which may suggest that the minor structural changes introduced by ProCS15-based annealing improves the accuracy of the protein structures. Having established that QM-based chemical shift prediction can deliver the same accuracy as empirical shift predictors we hope this can help increase the accuracy of related approaches such as QM/MM or linear scaling approaches or interpreting protein structural dynamics from QM-derived chemical shift.

  11. KSC-2009-2323

    NASA Image and Video Library

    2009-03-18

    CAPE CANAVERAL, Fla. – At the Astrotech payload processing facility in Titusville, Fla., technicians apply the NOAA decal to the fairing that will encapsulate the GOES-O satellite during launch. The latest Geostationary Operational Environmental Satellite, GOES-O was developed by NASA for the National Oceanic and Atmospheric Administration, or NOAA. The GOES satellites continuously provide observations of 60 percent of the Earth including the continental United States, providing weather monitoring and forecast operations as well as a continuous and reliable stream of environmental information and severe weather warnings. Once in orbit, GOES-O will be designated GOES-14, and NASA will provide on-orbit checkout and then transfer operational responsibility to NOAA. The GOES-O satellite is targeted to launch April 28 onboard a United Launch Alliance Delta IV expendable launch vehicle. Photo credit: NASA/Kim Shiflett

  12. KENNEDY SPACE CENTER, FLA. - Frank T. Brogan, president of the Florida Atlantic University, speaks at a dedication and ribbon-cutting ceremony for the Space Life Sciences Lab hosted by NASA-Kennedy Space Center and the state of Florida at the new lab. Completed in August, the facility encompasses more than 100,000 square feet and was formerly known as the Space Experiment Research and Processing Laboratory or SERPL. The state, through the Florida Space Authority, built the research lab which is host to NASA, NASA’s Life Sciences Services contractor Dynamac Corp., Bionetics Corp., and researchers from the University of Florida. Dynamac Corp. leases the facility. The Florida Space Research Institute is responsible for gaining additional tenants from outside the NASA community.

    NASA Image and Video Library

    2003-11-19

    KENNEDY SPACE CENTER, FLA. - Frank T. Brogan, president of the Florida Atlantic University, speaks at a dedication and ribbon-cutting ceremony for the Space Life Sciences Lab hosted by NASA-Kennedy Space Center and the state of Florida at the new lab. Completed in August, the facility encompasses more than 100,000 square feet and was formerly known as the Space Experiment Research and Processing Laboratory or SERPL. The state, through the Florida Space Authority, built the research lab which is host to NASA, NASA’s Life Sciences Services contractor Dynamac Corp., Bionetics Corp., and researchers from the University of Florida. Dynamac Corp. leases the facility. The Florida Space Research Institute is responsible for gaining additional tenants from outside the NASA community.

  13. KENNEDY SPACE CENTER, FLA. - Dignitaries, invited guests, space center employees, and the media gather for a dedication and ribbon-cutting ceremony for the Space Life Sciences Lab hosted by NASA-Kennedy Space Center and the state of Florida at the new lab. Completed in August, the facility encompasses more than 100,000 square feet and was formerly known as the Space Experiment Research and Processing Laboratory or SERPL. The state, through the Florida Space Authority, built the research lab which is host to NASA, NASA’s Life Sciences Services contractor Dynamac Corp., Bionetics Corp., and researchers from the University of Florida. Dynamac Corp. leases the facility. The Florida Space Research Institute is responsible for gaining additional tenants from outside the NASA community.

    NASA Image and Video Library

    2003-11-19

    KENNEDY SPACE CENTER, FLA. - Dignitaries, invited guests, space center employees, and the media gather for a dedication and ribbon-cutting ceremony for the Space Life Sciences Lab hosted by NASA-Kennedy Space Center and the state of Florida at the new lab. Completed in August, the facility encompasses more than 100,000 square feet and was formerly known as the Space Experiment Research and Processing Laboratory or SERPL. The state, through the Florida Space Authority, built the research lab which is host to NASA, NASA’s Life Sciences Services contractor Dynamac Corp., Bionetics Corp., and researchers from the University of Florida. Dynamac Corp. leases the facility. The Florida Space Research Institute is responsible for gaining additional tenants from outside the NASA community.

  14. KENNEDY SPACE CENTER, FLA. - Capt. Winston Scott, executive director of the Florida Space Authority, speaks at a dedication and ribbon-cutting ceremony for the Space Life Sciences Lab hosted by NASA-Kennedy Space Center and the state of Florida at the new lab. Completed in August, the facility encompasses more than 100,000 square feet and was formerly known as the Space Experiment Research and Processing Laboratory or SERPL. The state, through the Florida Space Authority, built the research lab which is host to NASA, NASA’s Life Sciences Services contractor Dynamac Corp., Bionetics Corp., and researchers from the University of Florida. Dynamac Corp. leases the facility. The Florida Space Research Institute is responsible for gaining additional tenants from outside the NASA community.

    NASA Image and Video Library

    2003-11-19

    KENNEDY SPACE CENTER, FLA. - Capt. Winston Scott, executive director of the Florida Space Authority, speaks at a dedication and ribbon-cutting ceremony for the Space Life Sciences Lab hosted by NASA-Kennedy Space Center and the state of Florida at the new lab. Completed in August, the facility encompasses more than 100,000 square feet and was formerly known as the Space Experiment Research and Processing Laboratory or SERPL. The state, through the Florida Space Authority, built the research lab which is host to NASA, NASA’s Life Sciences Services contractor Dynamac Corp., Bionetics Corp., and researchers from the University of Florida. Dynamac Corp. leases the facility. The Florida Space Research Institute is responsible for gaining additional tenants from outside the NASA community.

  15. KENNEDY SPACE CENTER, FLA. - Dynamac employees (from left) Larry Burns, Debbie Wells and Michelle Crouch talk in a conference room of the Space Life Sciences Lab (SLSL), formerly known as the Space Experiment Research and Processing Laboratory (SERPL). They have been transferring equipment from Hangar L. The new lab is a state-of-the-art facility being built for ISS biotechnology research. Developed as a partnership between NASA-KSC and the State of Florida, NASA’s life sciences contractor will be the primary tenant of the facility, leasing space to conduct flight experiment processing and NASA-sponsored research. About 20 percent of the facility will be available for use by Florida’s university researchers through the Florida Space Research Institute.

    NASA Image and Video Library

    2003-09-10

    KENNEDY SPACE CENTER, FLA. - Dynamac employees (from left) Larry Burns, Debbie Wells and Michelle Crouch talk in a conference room of the Space Life Sciences Lab (SLSL), formerly known as the Space Experiment Research and Processing Laboratory (SERPL). They have been transferring equipment from Hangar L. The new lab is a state-of-the-art facility being built for ISS biotechnology research. Developed as a partnership between NASA-KSC and the State of Florida, NASA’s life sciences contractor will be the primary tenant of the facility, leasing space to conduct flight experiment processing and NASA-sponsored research. About 20 percent of the facility will be available for use by Florida’s university researchers through the Florida Space Research Institute.

  16. KENNEDY SPACE CENTER, FLA. - Dynamac employees Debbie Wells, Michelle Crouch and Larry Burns are silhouetted as they talk inside a conference room of the Space Life Sciences Lab (SLSL), formerly known as the Space Experiment Research and Processing Laboratory (SERPL). They have been transferring equipment from Hangar L. The new lab is a state-of-the-art facility being built for ISS biotechnology research. Developed as a partnership between NASA-KSC and the State of Florida, NASA’s life sciences contractor will be the primary tenant of the facility, leasing space to conduct flight experiment processing and NASA-sponsored research. About 20 percent of the facility will be available for use by Florida’s university researchers through the Florida Space Research Institute.

    NASA Image and Video Library

    2003-09-10

    KENNEDY SPACE CENTER, FLA. - Dynamac employees Debbie Wells, Michelle Crouch and Larry Burns are silhouetted as they talk inside a conference room of the Space Life Sciences Lab (SLSL), formerly known as the Space Experiment Research and Processing Laboratory (SERPL). They have been transferring equipment from Hangar L. The new lab is a state-of-the-art facility being built for ISS biotechnology research. Developed as a partnership between NASA-KSC and the State of Florida, NASA’s life sciences contractor will be the primary tenant of the facility, leasing space to conduct flight experiment processing and NASA-sponsored research. About 20 percent of the facility will be available for use by Florida’s university researchers through the Florida Space Research Institute.

  17. KENNEDY SPACE CENTER, FLA. - Ivan Rodriguez, with Bionetics, and Michelle Crouch and Larry Burns, with Dynamac, carry boxes of equipment into the Space Life Sciences Lab (SLSL), formerly known as the Space Experiment Research and Processing Laboratory (SERPL). They are transferring equipment from Hangar L. The new lab is a state-of-the-art facility being built for ISS biotechnology research. Developed as a partnership between NASA-KSC and the State of Florida, NASA’s life sciences contractor will be the primary tenant of the facility, leasing space to conduct flight experiment processing and NASA-sponsored research. About 20 percent of the facility will be available for use by Florida’s university researchers through the Florida Space Research Institute.

    NASA Image and Video Library

    2003-09-10

    KENNEDY SPACE CENTER, FLA. - Ivan Rodriguez, with Bionetics, and Michelle Crouch and Larry Burns, with Dynamac, carry boxes of equipment into the Space Life Sciences Lab (SLSL), formerly known as the Space Experiment Research and Processing Laboratory (SERPL). They are transferring equipment from Hangar L. The new lab is a state-of-the-art facility being built for ISS biotechnology research. Developed as a partnership between NASA-KSC and the State of Florida, NASA’s life sciences contractor will be the primary tenant of the facility, leasing space to conduct flight experiment processing and NASA-sponsored research. About 20 percent of the facility will be available for use by Florida’s university researchers through the Florida Space Research Institute.

  18. KENNEDY SPACE CENTER, FLA. - Dynamac employees (from left) Larry Burns, Debbie Wells and Neil Yorio carry boxes of hardware into the Space Life Sciences Lab (SLSL), formerly known as the Space Experiment Research and Processing Laboratory (SERPL). They are transferring equipment from Hangar L. The new lab is a state-of-the-art facility being built for ISS biotechnology research. Developed as a partnership between NASA-KSC and the State of Florida, NASA’s life sciences contractor will be the primary tenant of the facility, leasing space to conduct flight experiment processing and NASA-sponsored research. About 20 percent of the facility will be available for use by Florida’s university researchers through the Florida Space Research Institute.

    NASA Image and Video Library

    2003-09-10

    KENNEDY SPACE CENTER, FLA. - Dynamac employees (from left) Larry Burns, Debbie Wells and Neil Yorio carry boxes of hardware into the Space Life Sciences Lab (SLSL), formerly known as the Space Experiment Research and Processing Laboratory (SERPL). They are transferring equipment from Hangar L. The new lab is a state-of-the-art facility being built for ISS biotechnology research. Developed as a partnership between NASA-KSC and the State of Florida, NASA’s life sciences contractor will be the primary tenant of the facility, leasing space to conduct flight experiment processing and NASA-sponsored research. About 20 percent of the facility will be available for use by Florida’s university researchers through the Florida Space Research Institute.

  19. KSC00pp1091

    NASA Image and Video Library

    2000-08-06

    During opening ceremonies of the 2000 International Law Enforcement Games, astronaut Sam Durrance addresses an audience of 1,850 participants and their families. Held in the KSC Visitor Complex Rocket Garden, the ceremony included parades, torch lighting and a tug of war. The games feature officers from 15 countries and 37 United States in competitions around Brevard County, Fla

  20. KSC-00pp1091

    NASA Image and Video Library

    2000-08-06

    During opening ceremonies of the 2000 International Law Enforcement Games, astronaut Sam Durrance addresses an audience of 1,850 participants and their families. Held in the KSC Visitor Complex Rocket Garden, the ceremony included parades, torch lighting and a tug of war. The games feature officers from 15 countries and 37 United States in competitions around Brevard County, Fla

  1. 76 FR 66965 - Treasure Coast Specialty Pharmacy Decision and Order

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-28

    ... pharmacist that is so licensed. Further, citing Federgo v. Department of Professional Regulation, 452 So.2d 1063 (Fla. 3rd DCA 1984), the Respondents state that alleged wrongdoing of a pharmacist does not... registered as a pharmacist, but instead permits a pharmacy to designate managerial authority to a registered...

  2. KSC-04PD-1959

    NASA Technical Reports Server (NTRS)

    2004-01-01

    KENNEDY SPACE CENTER, FLA. The Damage Assessment Recovery Team (DART) meets at the NASA KSC News Center following Hurricane Jeanne. At left (red shirt) is Center Director Jim Kennedy and Media Services Division Chief Mike Rein. A category 3 storm, Jeanne barreled through Central Florida Sept. 25-26, the fourth hurricane in 6 weeks to batter the state.

  3. KSC-04pd1959

    NASA Image and Video Library

    2004-09-27

    KENNEDY SPACE CENTER, FLA. - The Damage Assessment Recovery Team (DART) meets at the NASA KSC News Center following Hurricane Jeanne. At left (red shirt) is Center Director Jim Kennedy and Media Services Division Chief Mike Rein. A category 3 storm, Jeanne barreled through Central Florida Sept. 25-26, the fourth hurricane in 6 weeks to batter the state.

  4. KSC-04pd1919

    NASA Image and Video Library

    2004-09-27

    KENNEDY SPACE CENTER, FLA. - In the Orbiter Processing Facility, the wheel on Atlantis is covered in plastic that protected it from possible damage by Hurricane Jeanne. The storm ravaged Central Florida for 21 hours as it crossed the shoreline on the east coast Sept. 25-26. This was the fourth hurricane in 6 weeks to batter the state.

  5. KSC-2010-5322

    NASA Image and Video Library

    2010-08-23

    CAPE CANAVERAL, Fla. -- At NASA's Kennedy Space Center in Florida, two manatees congregate in brackish water off State Road 3, near the center's north guard gate. Kennedy coexists with the Merritt Island National Wildlife Refuge, habitat to more than 310 species of birds, 25 mammals, 117 fish and 65 amphibians and reptiles. Photo credit: NASA/Frank Michaux

  6. KENNEDY SPACE CENTER, FLA. - During power-up of the orbiter Discovery in the Orbiter Processing Facility, a technician (left) looks at the circuit breaker lights in the cabin. Discovery has been undergoing Orbiter Major Modifications in the past year, ranging from wiring, control panels and black boxes to gaseous and fluid systems tubing and components. These systems were deserviced, disassembled, inspected, modified, reassembled, checked out and reserviced, as were most other systems onboard. The work includes the installation of the Multifunction Electronic Display Subsystem (MEDS) - a state-of-the-art “glass cockpit.”

    NASA Image and Video Library

    2003-08-27

    KENNEDY SPACE CENTER, FLA. - During power-up of the orbiter Discovery in the Orbiter Processing Facility, a technician (left) looks at the circuit breaker lights in the cabin. Discovery has been undergoing Orbiter Major Modifications in the past year, ranging from wiring, control panels and black boxes to gaseous and fluid systems tubing and components. These systems were deserviced, disassembled, inspected, modified, reassembled, checked out and reserviced, as were most other systems onboard. The work includes the installation of the Multifunction Electronic Display Subsystem (MEDS) - a state-of-the-art “glass cockpit.”

  7. Construction of recombinant Mip-FlaA dominant epitope vaccine against Legionella pneumophila and evaluation of the immunogenicity and protective immunity.

    PubMed

    He, Jinlei; Zhang, Junrong; He, Yanxia; Huang, Fan; Li, Jiao; Chen, Qiwei; Chen, Dali; Chen, Jianping

    2016-02-01

    Legionnaires' disease, a kind of systemic disease with pneumonia as the main manifestation, is caused by Legionella pneumophila (L. pneumophila). In order to prevent the disease, we optimized Mip and FlaA, the virulence factors of L. pneumophila, to design recombinant Mip-FlaA dominant epitope vaccine against the pathogen. Firstly, the coding sequences of mip and flaA were optimized by DNAStar software and Expasy protein analysis system, and then, the tertiary structure and function of recombinant Mip-FlaA were predicted by PHYRE2 Protein Fold Recognition Server. After that, the optimized mip, flaA and mip-flaA were cloned, expressed and purified, and the proteins were used as dominant epitope vaccines to immunize BABL/c mice. Moreover, the IgG titers, histological changes in lung and the level of TNF-α, IFN-γ, IL-6 and IL-1β were detected to reflect the immunogenicity and protective immunity of the vaccines. The results of SDS-PAGE and Western blot proved the recombinant Mip-FlaA was successfully expressed. ELISA results of IgG titers and these cytokines showed Mip-FlaA group was capable to induce the strongest immune response, compared to PBS, Mip and FlaA groups. In addition, histopathology analysis demonstrated the mice immunized with Mip-FlaA showed better immune protection. Therefore, the work indicated that the above-described biological tools were useful in optimization of epitope vaccine. Antigenic characterization and immune protection of recombinant Mip-FlaA would be of great value in understanding the immunopathogenesis of the disease and in developing possible vaccine against the pathogen.

  8. Flagellin Diversity in Clostridium botulinum Groups I and II: a New Strategy for Strain Identification▿

    PubMed Central

    Paul, Catherine J.; Twine, Susan M.; Tam, Kevin J.; Mullen, James A.; Kelly, John F.; Austin, John W.; Logan, Susan M.

    2007-01-01

    Strains of Clostridium botulinum are traditionally identified by botulinum neurotoxin type; however, identification of an additional target for typing would improve differentiation. Isolation of flagellar filaments and analysis by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) showed that C. botulinum produced multiple flagellin proteins. Nano-liquid chromatography-tandem mass spectrometry (nLC-MS/MS) analysis of in-gel tryptic digests identified peptides in all flagellin bands that matched two homologous tandem flagellin genes identified in the C. botulinum Hall A genome. Designated flaA1 and flaA2, these open reading frames encode the major structural flagellins of C. botulinum. Colony PCR and sequencing of flaA1/A2 variable regions classified 80 environmental and clinical strains into group I or group II and clustered isolates into 12 flagellar types. Flagellar type was distinct from neurotoxin type, and epidemiologically related isolates clustered together. Sequencing a larger PCR product, obtained during amplification of flaA1/A2 from type E strain Bennett identified a second flagellin gene, flaB. LC-MS analysis confirmed that flaB encoded a large type E-specific flagellin protein, and the predicted molecular mass for FlaB matched that observed by SDS-PAGE. In contrast, the molecular mass of FlaA was 2 to 12 kDa larger than the mass predicted by the flaA1/A2 sequence of a given strain, suggesting that FlaA is posttranslationally modified. While identification of FlaB, and the observation by SDS-PAGE of different masses of the FlaA proteins, showed the flagellin proteins of C. botulinum to be diverse, the presence of the flaA1/A2 gene in all strains examined facilitates single locus sequence typing of C. botulinum using the flagellin variable region. PMID:17351097

  9. POTENTIALLY PATHOGENIC FREE-LIVING AMOEBAE IN SOME FLOOD-AFFECTED AREAS DURING 2011 CHIANG MAI FLOOD

    PubMed Central

    Wannasan, Anchalee; Uparanukraw, Pichart; Songsangchun, Apichart; Morakote, Nimit

    2013-01-01

    SUMMARY The survey was carried out to investigate the presence of potentially pathogenic free-living amoebae (FLA) during flood in Chiang Mai, Thailand in 2011. From different crisis flood areas, seven water samples were collected and tested for the presence of amoebae using culture and molecular methods. By monoxenic culture, FLA were detected from all samples at 37 °C incubation. The FLA growing at 37 °C were morphologically identified as Acanthamoeba spp., Naegleria spp. and some unidentified amoebae. Only three samples (42.8%), defined as thermotolerant FLA, continued to grow at 42 °C. By molecular methods, two non-thermotolerant FlA were shown to have 99% identity to Acanthamoeba sp. and 98% identity to Hartmannella vermiformis while the two thermotolerant FLA were identified as Echinamoeba exundans (100% identity) and Hartmannella sp. (99% identity). This first report of the occurrence of FLA in water during the flood disaster will provide information to the public to be aware of potentially pathogenic FLA. PMID:24213194

  10. Potentially pathogenic free-living amoebae in some flood-affected areas during 2011 Chiang Mai flood.

    PubMed

    Wannasan, Anchalee; Uparanukraw, Pichart; Songsangchun, Apichart; Morakote, Nimit

    2013-01-01

    The survey was carried out to investigate the presence of potentially pathogenic free-living amoebae (FLA) during flood in Chiang Mai, Thailand in 2011. From different crisis flood areas, seven water samples were collected and tested for the presence of amoebae using culture and molecular methods. By monoxenic culture, FLA were detected from all samples at 37 °C incubation. The FLA growing at 37 °C were morphologically identified as Acanthamoeba spp., Naegleria spp. and some unidentified amoebae. Only three samples (42.8%), defined as thermotolerant FLA, continued to grow at 42 °C. By molecular methods, two non-thermotolerant FlA were shown to have 99% identity to Acanthamoeba sp. and 98% identity to Hartmannella vermiformis while the two thermotolerant FLA were identified as Echinamoeba exundans (100% identity) and Hartmannella sp. (99% identity). This first report of the occurrence of FLA in water during the flood disaster will provide information to the public to be aware of potentially pathogenic FLA.

  11. Rare earth chalcogenide Ce3Te4 as high efficiency high temperature thermoelectric material

    NASA Astrophysics Data System (ADS)

    Wang, Xiaochun; Yang, Ronggui; Zhang, Yong; Zhang, Peihong; Xue, Yu

    2011-05-01

    The electronic band structures of Ce3Te4 have been studied using the first-principles density-functional theory calculations. It is found that the density of states of Ce3Te4 has a very high delta-shaped peak appearing 0.21 eV above the Fermi level, which mainly comes from the f orbital electrons of the rare-earth element Ce. Using the simple theory proposed by Mahan and Sofo, [Proc. Natl. Acad. Sci. U.S.A. 93, 7436 (1996)], we obtain an ideal value of zT=13.5 for Ce3Te4 at T=1200 K, suggesting that the rare-earth chalcogenide Ce3Te4 could be a promising high efficiency high temperature thermoelectric material.

  12. Measurement of the Lamb shift in the hydrogen atom (n = 2)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sokolov, Y.L.; Yakovlev, V.P.

    1982-07-01

    A principle is proposed for the observation of the stationary interference pattern of two phase-shifted components of the 2p (or 2s) state of the hydrogen atom (Yu. L. Sokolov, Sov. Phys. JETP 36, 243 (1973)); (Proc. 6-th Internat. Conf. on Atomic Phys., Riga, 1978, p. 207). An atomic interferometer, a device analogous in principle to a two-channel optical (such as Michelson's) interferometer, is used to measure the frequency of the (2s/sub 1/2/, F = 0)--(2p/sub 1/2/, F = 0) transition in the hydrogen atom, which is found to equal 909.9014 +- 0.0019 MHz. The corresponding Lamb shift is delta(H, nmore » = 2) = 1057.8594 +- 0.0019 MHz.« less

  13. Polypodium sp. (Coelenterata) infection of paddlefish (Polyodon spathula) eggs

    USGS Publications Warehouse

    Suppes, V. Charles; Meyer, Fred P.

    1975-01-01

    Parasitism of fish by coelenterates is rare and the first North American infection was reported in sturgeon (Hoffman et al., 1974, J Parasitol 60: 548-550). In the USSR parasitism of sturgeon (Acipenser sp.) eggs by the coelenterate Polypodium hydriforme Ussov 1885 has long been reported and investigated [Raikova, 1959, in Parasites of Freshwater Fish and the Biological Basis for their Control. Bull State Sci Res Inst Lake and River Fish. XLIX. Eng. transl. No. TT61-31056, O. T. S., U. S. Dep. Commerce, Washington, D. C., 1962, 235 p.: Raikova, 1973, (Proc Second Internat Symp on Cnidaria), Seto Marine Biological Laboratory 20: 165-173]. This report represents the first known infection of Polypodium in the paddlefish (Polyodon spathula).

  14. pROC-Chemotype Plots Enhance the Interpretability of Benchmarking Results in Structure-Based Virtual Screening.

    PubMed

    Ibrahim, Tamer M; Bauer, Matthias R; Dörr, Alexander; Veyisoglu, Erdem; Boeckler, Frank M

    2015-11-23

    Recently, we have reported a systematic comparison of molecular preparation protocols (using MOE or Maestro) in combination with two docking tools (GOLD or Glide), employing our DEKOIS 2.0 benchmark sets. Herein, we demonstrate how comparable settings of data preparation protocols can affect the profile and AUC of pROC curves based on variations in chemotype enrichment. We show how the recognition of different classes of chemotypes can affect the docking performance, particularly in the early enrichment, and monitor changes in this recognition behavior based on score normalization and rescoring strategies. For this, we have developed "pROC-Chemotype", which is an automated protocol that matches and visualizes ligand chemotype information together with potency classes in the pROC profiles obtained by docking. This tool enhances the understanding of the influence of chemotype recognition in early enrichment, but also reveals trends of impaired recognition of chemotype classes at the end of the score-ordered rank. Identifying such issues helps to devise score-normalization strategies to overcome this potential bias in an intuitive manner. Furthermore, strong perturbations in chemotype ranking between different methods can help to identify the underlying reasons (e.g., changes in the protonation/tautomerization state). It also assists in the selection of appropriate scoring functions that are capable to retrieve more potent and diverse hits. In summary, we demonstrate how this new tool can be utilized to identify and highlight chemotype-specific behavior, e.g., in dataset preparation. This can help to overcome some chemistry-related bias in virtual screening campaigns. pROC-Chemotype is made freely available at www.dekois.com.

  15. Environmental Impact Research Program. Transplanting of the Seagrasses Halodule wrightii, Syringodium filiforme, and Thalassia testudinum for Sediment Stabilization and Habitat Development in the Southeast Region of the United States.

    DTIC Science & Technology

    1987-07-01

    TRANSPLANTING OF THE SEAGRASSES HALODULE WRIGHT/I, SYRINGODIUM FILIFORME, AND THALASSIA TESTUDINUM * - -FOR SEDIMENT STABILIZATION AND HABITAT DEVELOPMENT IN...SYRINGODIUM FILIFORME, AND THALASSIA TESTUDINUM FOR SEDIMENT STABILIZATION AND HABITAT DEVELOPMENT IN THE SOUTHEAST REGION OF THE UNITED STATES PART...Tallahassee,. Fla., 95 pp. den Hartog, C. 1971. The dynamic aspect in the ecology of seagrass communities. Thalassia Jugosl. 7:101-112. Derrenbacker, J.A., and

  16. Acanthamoeba and other free-living amoebae in bat guano, an extreme habitat.

    PubMed

    Mulec, Janez; Dietersdorfer, Elisabeth; Üstüntürk-Onan, Miray; Walochnik, Julia

    2016-04-01

    Several representatives of the so-called free-living amoebae (FLA) are of medical relevance, not only as facultative pathogens but also as vehicles for pathogenic bacteria. Some FLA can survive and even grow under extreme environmental conditions. Bat guano is an exceptional habitat, the conditions becoming gradually more extreme with aging. In the current study, samples of bat guano of different ages from five caves in Slovenia were screened for the presence of FLA. FLA were isolated from almost all guano samples, including guano with a pH of 3.5. Only the two samples that had been drawn from >20-year-old guano were negative for FLA. Generally, FLA diversity correlated to high concentrations of cultivable bacteria (∼10(8) CFU/g) and fungi (∼10(5) CFU/g). Interestingly, the absence of FLA in seasoned guanos was mirrored by the presence of dictyostelid slime moulds. The isolated amoebae were identified as belonging to the genera Acanthamoeba, Copromyxa, Naegleria, Sappinia, Tetramitus, Thecamoeba, Vahlkampfia, Vannella and Vermamoeba. To the best of our knowledge, this is the first study on the diversity of FLA in guano.

  17. Protection against Legionnaire's Disease: Recombinant Flagellin A of Legionella pneumophila Can Induce Protective Immunity against Bacteremia in a BALB/c Murine Model.

    PubMed

    Mohabati Mobarez, Ashraf; Ahmadrajabi, Roya; Khoramabadi, Nima; Salmanian, Ali-Hatef

    2017-01-01

    To investigate the immunoprotective effects of the recombinant type A flagellin (FLA), the flaA gene of Legionella pneumophila serogroup 1 strain Paris was cloned into pET28a(+). Recombinant FLA (rFLA) was overexpressed in E. coli BL21 (DE3) and purified by Ni2+ exchange chromatography. Female BALB/c aged 6-8 weeks were immunized with 20 μg of rFLA. Nonimmunized mice along with mice inoculated with a sublethal dose of live L. pneumophila intravenously were considered as negative and positive controls, respectively. A significant serum antibody response was observed in female BALB/c mice immunized with rFLA. Production of IFN-γ and IL-12, and TNF-α in the serum and the splenocyte cultures, and antigen-specific splenocyte proliferation suggested a strong innate and adaptive cell-mediated immunity response in rFLA-immunized mice. Intravenous lethal challenge with L. pneumophila serogroup 1 (strain Paris) showed that 60% of mice immunized with rFLA survived in a 10-day follow-up survey. These results show that rFLA from L. pneumophila can elicit strong innate and adaptive immune responses and suggest the possibility of a long-term immunity against lethal challenge with L. pneumophila. © 2017 S. Karger AG, Basel.

  18. PSHREG: A SAS macro for proportional and nonproportional subdistribution hazards regression

    PubMed Central

    Kohl, Maria; Plischke, Max; Leffondré, Karen; Heinze, Georg

    2015-01-01

    We present a new SAS macro %pshreg that can be used to fit a proportional subdistribution hazards model for survival data subject to competing risks. Our macro first modifies the input data set appropriately and then applies SAS's standard Cox regression procedure, PROC PHREG, using weights and counting-process style of specifying survival times to the modified data set. The modified data set can also be used to estimate cumulative incidence curves for the event of interest. The application of PROC PHREG has several advantages, e.g., it directly enables the user to apply the Firth correction, which has been proposed as a solution to the problem of undefined (infinite) maximum likelihood estimates in Cox regression, frequently encountered in small sample analyses. Deviation from proportional subdistribution hazards can be detected by both inspecting Schoenfeld-type residuals and testing correlation of these residuals with time, or by including interactions of covariates with functions of time. We illustrate application of these extended methods for competing risk regression using our macro, which is freely available at: http://cemsiis.meduniwien.ac.at/en/kb/science-research/software/statistical-software/pshreg, by means of analysis of a real chronic kidney disease study. We discuss differences in features and capabilities of %pshreg and the recent (January 2014) SAS PROC PHREG implementation of proportional subdistribution hazards modelling. PMID:25572709

  19. Modification of the D2 radial wavefunction by near resonant compact states

    NASA Astrophysics Data System (ADS)

    Hagelstein, Peter L.

    2003-03-01

    We have proposed that phonon exchange can occur in the presence of a highly excited optical phonon mode during a dd-fusion reaction. We have also suggested (P. L. Hagelstein, Bull. APS 45, 235 (2000)) at new second-order site-other-site reactions can occur when the energy of a fusion reaction is transferred elsewhere. Fast particle ejecta from the experiments of Chambers( G. P. Chambers, et al, J. Fusion Energy, Vol. 9, p. 281 (1990).) and of Cecil (F. E. Cecil, et al, AIP Conf. Proc. Vol. 228, p. 383 (1990).) appear to be consistent with such a mechanism, in which a dd-fusion reaction at one site is coupled to a disintegration at another site. The dominant process of this type is the null reaction in which dd-fusion is coupled to He-4 dissociation. This process can lead to compact dd-states(P. L. Hagelstein, Bull. APS 2001), and is consistent with the Kasagi experiment(J. Kasagi et al, J. Phys. Soc. Japan 64, 777 (1995). ). We find that compact states near resonance with the molecular D2 states changes the radial wavefunction at small r.

  20. Detecting the Length of Double-stranded DNA with Solid State Nanopores

    NASA Astrophysics Data System (ADS)

    Li, Jiali; Gershow, Marc; Stein, Derek; Qun, Cai; Brandin, Eric; Wang, Hui; Huang, Albert; Branton, Dan; Golovchenko, Jene

    2003-03-01

    We report on the use of nanometer scale diameter, solid-state nanopores as single molecule detectors of double stranded DNA molecules. These solid-state nanopores are fabricated in thin membranes of silicon nitride, by ion beam sculpting 1. They produce discrete electronic signals: current blockages, when an electrically biased nanopore is exposed to DNA molecules in aqueous salt solutions. We demonstrate examples of such electronic signals for 3k base pairs (bp) and 10k bp double stranded DNA molecules, which suggest that these molecules are individually translocating through the nanopore during the detection process. The translocating time for the 10k bp double stranded DNA is about 3 times longer than the 3k bp, demonstrating that a solid-state nanopore device can be used to detect the lengths of double stranded DNA molecules. Similarities and differences with signals obtained from single stranded DNA in a biological nanopores are discussed 2. 1. Li, J., Stein, D., McMullan, C., Branton, D. Aziz, M. J. and Golovchenko, J. Ion Beam Sculpting at nanometer length scales. Nature 412, 166-169 (2001). 2. Meller, A., L. Nivon, E. Brandin, Golovchenko, J. & Branton, D. Proc. Natl. Acad. Sci. USA 97, 1079-1084 (2000).

  1. KSC-05PD-1596

    NASA Technical Reports Server (NTRS)

    2005-01-01

    KENNEDY SPACE CENTER, FLA. The NASA News Center at NASA Kennedy Space Center hums with activity as workers and volunteers behind the counter help the media during launch activities for Return to Flight mission STS-114. More than a thousand media representatives from 36 states, the District of Columbia and 32 countries converged on the News Center for the historic launch.

  2. KSC-05PD-1593

    NASA Technical Reports Server (NTRS)

    2005-01-01

    KENNEDY SPACE CENTER, FLA. Satellite trucks are lined up in the parking lot at the NASA Kennedy Space Center News Center to cover the launch of Space Shuttle Discovery on Return to Flight mission STS-114. More than a thousand media representatives from 36 states, the District of Columbia and 32 countries converged on the News Center for the historic launch.

  3. The Children's Foreign Language Anxiety Scale: Reliability and Validity

    ERIC Educational Resources Information Center

    Aydin, Selami; Harputlu, Leyla; Ustuk, Özgehan; Güzel, Serhat; Çelik, Seyda Savran

    2017-01-01

    Foreign language anxiety (FLA) has been mainly associated with adult language learners. Although FLA forms a serious problem in the foreign language learning process for all learners, the effects of FLA on children have been mainly overlooked. The underlying reason is that there is a lack of an appropriate measurement tool for FLA among children.…

  4. Steve Rummel | NREL

    Science.gov Websites

    Module Intercomparison," Proc. Solar Energies Technologies Review Meeting Nov. 7-10, 2005, NREL tech . Rummel, D.R. Myers, T.L. Stoffel, and D. Waddington, "A Comparison of Photovoltaic Calibration

  5. SFG characterization of a cationic ONLO dye in biological thin films

    NASA Astrophysics Data System (ADS)

    Johnson, Lewis E.; Casford, Michael T.; Elder, Delwin L.; Davies, Paul B.; Johal, Malkiat S.

    2013-10-01

    Biopolymer-based thin films, such as those composed of CTMA-DNA, can be used as a host material for NLOactive dyes for applications such as electro-optic (EO) switching and second harmonic generation. Previous work by Heckman et al. (Proc. SPIE 6401, 640108-2) has demonstrated functioning DNA-based EO modulators. Improved performance requires optimization of both the first hyperpolarizabilities (β) and degree of acentric ordering exhibited by the chromophores. The cationic dye DANPY-1 (Proc. SPIE 8464, 846409-D) has a high affinity for DNA and a substantial hyperpolarizability; however, its macroscopic ordering has not been previously characterized. We have characterized the acentric ordering of the dye using sum-frequency generation (SFG) vibrational spectroscopy in surface-immobilized DNA and on planar metal and dielectric surfaces.

  6. Quadratic Zeeman effect in hydrogen Rydberg states: Rigorous error estimates for energy eigenvalues, energy eigenfunctions, and oscillator strengths

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Falsaperla, P.; Fonte, G.

    1994-10-01

    A variational method, based on some results due to T. Kato [Proc. Phys. Soc. Jpn. 4, 334 (1949)], and previously discussed is here applied to the hydrogen atom in uniform magnetic fields of tesla in order to calculate, with a rigorous error estimate, energy eigenvalues, energy eigenfunctions, and oscillator strengths relative to Rydberg states up to just below the field-free ionization threshold. Making use of a basis (parabolic Sturmian basis) with a size varying from 990 up to 5050, we obtain, over the energy range of [minus]190 to [minus]24 cm[sup [minus]1], all of the eigenvalues and a good part ofmore » the oscillator strengths with a remarkable accuracy. This, however, decreases with increasing excitation energy and, thus, above [similar to][minus]24 cm[sup [minus]1], we obtain results of good accuracy only for eigenvalues ranging up to [similar to][minus]12 cm[sup [minus]1].« less

  7. Urea denatured state ensembles contain extensive secondary structure that is increased in hydrophobic proteins.

    PubMed

    Nick Pace, C; Huyghues-Despointes, Beatrice M P; Fu, Hailong; Takano, Kazufumi; Scholtz, J Martin; Grimsley, Gerald R

    2010-05-01

    The goal of this article is to gain a better understanding of the denatured state ensemble (DSE) of proteins through an experimental and computational study of their denaturation by urea. Proteins unfold to different extents in urea and the most hydrophobic proteins have the most compact DSE and contain almost as much secondary structure as folded proteins. Proteins that unfold to the greatest extent near pH 7 still contain substantial amounts of secondary structure. At low pH, the DSE expands due to charge-charge interactions and when the net charge per residue is high, most of the secondary structure is disrupted. The proteins in the DSE appear to contain substantial amounts of polyproline II conformation at high urea concentrations. In all cases considered, including staph nuclease, the extent of unfolding by urea can be accounted for using the data and approach developed in the laboratory of Wayne Bolen (Auton et al., Proc Natl Acad Sci 2007; 104:15317-15323).

  8. Alternative Electron-Transfer Channels Ensure Ultrafast Deactivation of Light-Induced Excited States in Riboflavin Binding Protein.

    PubMed

    Zanetti-Polzi, Laura; Aschi, Massimiliano; Amadei, Andrea; Daidone, Isabella

    2017-07-20

    Flavoproteins, containing flavin chromophores, are enzymes capable of transferring electrons at very high speeds. The ultrafast photoinduced electron-transfer (ET) kinetics of riboflavin binding protein to the excited riboflavin was studied by femtosecond spectroscopy and found to occur within a few hundred femtoseconds [ Zhong and Zewail, Proc. Natl. Acad. Sci. U.S.A. 2001, 98, 11867-11872 ]. This ultrafast kinetics was attributed to the presence of two aromatic rings that could transfer the electron to riboflavin: the side chains of tryptophan 156 and tyrosine 75. However, the underlying ET mechanism remained unclear. Here, using a hybrid quantum mechanical-molecular dynamics approach, we perform ET dynamics simulations taking into account the motion of the protein and the solvent upon ET. This approach reveals that ET occurs via a major reaction channel involving tyrosine 75 (83%) and a minor one involving tryptophan 156 (17%). We also show that the protein environment is designed to ensure the fast quenching of the riboflavin excited state.

  9. Protein structure refinement using a quantum mechanics-based chemical shielding predictor† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c6sc04344e Click here for additional data file.

    PubMed Central

    2017-01-01

    The accurate prediction of protein chemical shifts using a quantum mechanics (QM)-based method has been the subject of intense research for more than 20 years but so far empirical methods for chemical shift prediction have proven more accurate. In this paper we show that a QM-based predictor of a protein backbone and CB chemical shifts (ProCS15, PeerJ, 2016, 3, e1344) is of comparable accuracy to empirical chemical shift predictors after chemical shift-based structural refinement that removes small structural errors. We present a method by which quantum chemistry based predictions of isotropic chemical shielding values (ProCS15) can be used to refine protein structures using Markov Chain Monte Carlo (MCMC) simulations, relating the chemical shielding values to the experimental chemical shifts probabilistically. Two kinds of MCMC structural refinement simulations were performed using force field geometry optimized X-ray structures as starting points: simulated annealing of the starting structure and constant temperature MCMC simulation followed by simulated annealing of a representative ensemble structure. Annealing of the CHARMM structure changes the CA-RMSD by an average of 0.4 Å but lowers the chemical shift RMSD by 1.0 and 0.7 ppm for CA and N. Conformational averaging has a relatively small effect (0.1–0.2 ppm) on the overall agreement with carbon chemical shifts but lowers the error for nitrogen chemical shifts by 0.4 ppm. If an amino acid specific offset is included the ProCS15 predicted chemical shifts have RMSD values relative to experiments that are comparable to popular empirical chemical shift predictors. The annealed representative ensemble structures differ in CA-RMSD relative to the initial structures by an average of 2.0 Å, with >2.0 Å difference for six proteins. In four of the cases, the largest structural differences arise in structurally flexible regions of the protein as determined by NMR, and in the remaining two cases, the large structural change may be due to force field deficiencies. The overall accuracy of the empirical methods are slightly improved by annealing the CHARMM structure with ProCS15, which may suggest that the minor structural changes introduced by ProCS15-based annealing improves the accuracy of the protein structures. Having established that QM-based chemical shift prediction can deliver the same accuracy as empirical shift predictors we hope this can help increase the accuracy of related approaches such as QM/MM or linear scaling approaches or interpreting protein structural dynamics from QM-derived chemical shift. PMID:28451325

  10. KENNEDY SPACE CENTER, FLA. - Dignitaries, invited guests, space center employees, and the media show their appreciation for the speakers at a dedication and ribbon-cutting ceremony for the Space Life Sciences Lab hosted by NASA-Kennedy Space Center and the state of Florida at the new lab. Completed in August, the facility encompasses more than 100,000 square feet and was formerly known as the Space Experiment Research and Processing Laboratory or SERPL. The state, through the Florida Space Authority, built the research lab which is host to NASA, NASA’s Life Sciences Services contractor Dynamac Corp., Bionetics Corp., and researchers from the University of Florida. Dynamac Corp. leases the facility. The Florida Space Research Institute is responsible for gaining additional tenants from outside the NASA community.

    NASA Image and Video Library

    2003-11-19

    KENNEDY SPACE CENTER, FLA. - Dignitaries, invited guests, space center employees, and the media show their appreciation for the speakers at a dedication and ribbon-cutting ceremony for the Space Life Sciences Lab hosted by NASA-Kennedy Space Center and the state of Florida at the new lab. Completed in August, the facility encompasses more than 100,000 square feet and was formerly known as the Space Experiment Research and Processing Laboratory or SERPL. The state, through the Florida Space Authority, built the research lab which is host to NASA, NASA’s Life Sciences Services contractor Dynamac Corp., Bionetics Corp., and researchers from the University of Florida. Dynamac Corp. leases the facility. The Florida Space Research Institute is responsible for gaining additional tenants from outside the NASA community.

  11. 33 CFR 334.590 - Atlantic Ocean off Cape Canaveral, Fla.; Air Force missile testing area, Patrick Air Force Base...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ..., Fla.; Air Force missile testing area, Patrick Air Force Base, Fla. 334.590 Section 334.590 Navigation... RESTRICTED AREA REGULATIONS § 334.590 Atlantic Ocean off Cape Canaveral, Fla.; Air Force missile testing area... during firing periods to be specified by the Commander, Air Force Missile Test Center, Patrick Air Force...

  12. 33 CFR 334.590 - Atlantic Ocean off Cape Canaveral, Fla.; Air Force missile testing area, Patrick Air Force Base...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ..., Fla.; Air Force missile testing area, Patrick Air Force Base, Fla. 334.590 Section 334.590 Navigation... RESTRICTED AREA REGULATIONS § 334.590 Atlantic Ocean off Cape Canaveral, Fla.; Air Force missile testing area... during firing periods to be specified by the Commander, Air Force Missile Test Center, Patrick Air Force...

  13. 33 CFR 334.590 - Atlantic Ocean off Cape Canaveral, Fla.; Air Force missile testing area, Patrick Air Force Base...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ..., Fla.; Air Force missile testing area, Patrick Air Force Base, Fla. 334.590 Section 334.590 Navigation... RESTRICTED AREA REGULATIONS § 334.590 Atlantic Ocean off Cape Canaveral, Fla.; Air Force missile testing area... during firing periods to be specified by the Commander, Air Force Missile Test Center, Patrick Air Force...

  14. 33 CFR 334.590 - Atlantic Ocean off Cape Canaveral, Fla.; Air Force missile testing area, Patrick Air Force Base...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ..., Fla.; Air Force missile testing area, Patrick Air Force Base, Fla. 334.590 Section 334.590 Navigation... RESTRICTED AREA REGULATIONS § 334.590 Atlantic Ocean off Cape Canaveral, Fla.; Air Force missile testing area... during firing periods to be specified by the Commander, Air Force Missile Test Center, Patrick Air Force...

  15. KENNEDY SPACE CENTER, FLA. - Workers calibrate a tracking telescope, part of the Distant Object Attitude Measurement System (DOAMS), located in Cocoa Beach, Fla. The telescope provides optical support for launches from KSC and Cape Canaveral.

    NASA Image and Video Library

    2003-09-03

    KENNEDY SPACE CENTER, FLA. - Workers calibrate a tracking telescope, part of the Distant Object Attitude Measurement System (DOAMS), located in Cocoa Beach, Fla. The telescope provides optical support for launches from KSC and Cape Canaveral.

  16. KENNEDY SPACE CENTER, FLA. - A worker calibrates a tracking telescope, part of the Distant Object Attitude Measurement System (DOAMS), located in Cocoa Beach, Fla. The telescope provides optical support for launches from KSC and Cape Canaveral.

    NASA Image and Video Library

    2003-09-03

    KENNEDY SPACE CENTER, FLA. - A worker calibrates a tracking telescope, part of the Distant Object Attitude Measurement System (DOAMS), located in Cocoa Beach, Fla. The telescope provides optical support for launches from KSC and Cape Canaveral.

  17. On bipartite pure-state entanglement structure in terms of disentanglement

    NASA Astrophysics Data System (ADS)

    Herbut, Fedor

    2006-12-01

    Schrödinger's disentanglement [E. Schrödinger, Proc. Cambridge Philos. Soc. 31, 555 (1935)], i.e., remote state decomposition, as a physical way to study entanglement, is carried one step further with respect to previous work in investigating the qualitative side of entanglement in any bipartite state vector. Remote measurement (or, equivalently, remote orthogonal state decomposition) from previous work is generalized to remote linearly independent complete state decomposition both in the nonselective and the selective versions. The results are displayed in terms of commutative square diagrams, which show the power and beauty of the physical meaning of the (antiunitary) correlation operator inherent in the given bipartite state vector. This operator, together with the subsystem states (reduced density operators), constitutes the so-called correlated subsystem picture. It is the central part of the antilinear representation of a bipartite state vector, and it is a kind of core of its entanglement structure. The generalization of previously elaborated disentanglement expounded in this article is a synthesis of the antilinear representation of bipartite state vectors, which is reviewed, and the relevant results of [Cassinelli et al., J. Math. Anal. Appl. 210, 472 (1997)] in mathematical analysis, which are summed up. Linearly independent bases (finite or infinite) are shown to be almost as useful in some quantum mechanical studies as orthonormal ones. Finally, it is shown that linearly independent remote pure-state preparation carries the highest probability of occurrence. This singles out linearly independent remote influence from all possible ones.

  18. Shikimic Acid Ozonolysis is Influenced by its Physical State

    NASA Astrophysics Data System (ADS)

    Steimer, S.; Krieger, U. K.; Lampimäki, M.; Peter, T.; Ammann, M.

    2013-12-01

    Atmospheric aerosols play an important role in climate, air quality and human health. They undergo continuous transformation, changing their physical and chemical properties. Recent findings show that secondary organic aerosol (SOA) particles can form amorphous solids and semi-solids under atmospheric conditions [1]. Such physical states are highly viscous, leading to a decreased diffusivity within the bulk of the material. Inhibited mass transport could slow down chemical reactions, thereby increasing the lifetime of the organic compounds involved. First indications of such behavior were recently shown for the reaction of thin protein films with ozone [2] and formation of organonitrogen from ammonia uptake to α-pinene secondary organic material [3]. In this study, we investigated the influence of physical state on the ozonolysis of shikimic acid. This carboxylic acid is a constituent of biomass burning aerosols and used here as a proxy for oxygenated organic aerosol. The viscosity of the organic material was adjusted by varying the humidity of the system between 0% and 92% RH, assuming a correlation between the two parameters since water acts as a plasticizer. The system was probed with two complementary techniques: coated wall flow tube measurements, where the uptake of ozone is measured via loss from the gas phase and in situ X-ray microspectroscopy on single particles, where oxidation of the bulk can be observed. Additionally, data from electrodynamic balance measurements and kinetic modeling were used to facilitate data analysis. The dependence of the ozonolysis on relative humidity was clearly observed with both techniques. The coated wall flow tube measurements showed a long term, gradually changing ozone uptake over more than 15 hours, the magnitude of which varied over nearly two orders between driest and wettest conditions. It was possible to separate the uptake into two distinct kinetic regimes, the first of which displayed a Langmuir-Hinshelwood type behavior regarding the ozone gas phase concentration. Microspectroscopy showed that the speed at which the characteristic double bond peak of shikimic acid disappeared was humidity dependent. The measured humidity dependence supports the hypothesis that the uptake coefficient is highly dependent on the diffusion coefficients of ozone and/or shikimic acid in the organic film. [1] Nature, 2010, 467, 824-827. [2] Proc. Natl. Acad. Sci. U. S. A., 2011, 108, 11003-11008. [3] Proc. Natl. Acad. Sci. U. S. A., 2012, 109, 17354-17359.

  19. Opening ceremonies of the 2000 Law Enforcement Games held at KSC

    NASA Technical Reports Server (NTRS)

    2000-01-01

    During opening ceremonies of the 2000 International Law Enforcement Games, astronaut Sam Durrance addresses an audience of 1,850 participants and their families. Held in the KSC Visitor Complex Rocket Garden, the ceremony included parades, torch lighting and a tug of war. The games feature officers from 15 countries and 37 United States in competitions around Brevard County, Fla.

  20. KSC00pp1089

    NASA Image and Video Library

    2000-08-06

    Canadian police officers gather in the KSC Visitor Complex Rocket Garden during opening ceremonies of the 2000 International Law Enforcement Games. More than 1,850 participants and their families took part in the opening, held in the Rocket Garden. The ceremony included parades, torch lighting and a tug of war. The games feature officers from 15 countries and 37 United States in competitions around Brevard County, Fla

  1. KSC-00pp1089

    NASA Image and Video Library

    2000-08-06

    Canadian police officers gather in the KSC Visitor Complex Rocket Garden during opening ceremonies of the 2000 International Law Enforcement Games. More than 1,850 participants and their families took part in the opening, held in the Rocket Garden. The ceremony included parades, torch lighting and a tug of war. The games feature officers from 15 countries and 37 United States in competitions around Brevard County, Fla

  2. KSC00pp1090

    NASA Image and Video Library

    2000-08-06

    A crowd of police officers and their families attend opening ceremonies of the 2000 International Law Enforcement Games. Held in the KSC Visitor Complex Rocket Garden, the ceremony hosted more than 1,850 participants and their families for events that included parades, torch lighting and a tug of war. The games feature officers from 15 countries and 37 United States in competitions around Brevard County, Fla

  3. KSC-00pp1090

    NASA Image and Video Library

    2000-08-06

    A crowd of police officers and their families attend opening ceremonies of the 2000 International Law Enforcement Games. Held in the KSC Visitor Complex Rocket Garden, the ceremony hosted more than 1,850 participants and their families for events that included parades, torch lighting and a tug of war. The games feature officers from 15 countries and 37 United States in competitions around Brevard County, Fla

  4. KSC-2009-3311

    NASA Image and Video Library

    2009-05-28

    CAPE CANAVERAL, Fla. – NASA Kennedy Space Center Bob Cabana talks to guests at the annual Community Leaders Breakfast held in the Debus Center at Kennedy Space Center's Visitor Complex. Community leaders, business executives, educators, community organizers and state and local government heard Cabana provide an overview of operations at the space center and a look ahead at upcoming missions and activities. Photo credit: NASA/Kim Shiflett

  5. KSC-2009-3308

    NASA Image and Video Library

    2009-05-28

    CAPE CANAVERAL, Fla. – NASA Kennedy Space Center Bob Cabana talks to guests at the annual Community Leaders Breakfast held in the Debus Center at Kennedy's Visitor Complex. Community leaders, business executives, educators, community organizers and state and local government heard Cabana provide an overview of operations at the space center and a look ahead at upcoming missions and activities. Photo credit: NASA/Kim Shiflett

  6. KSC-2009-3309

    NASA Image and Video Library

    2009-05-28

    CAPE CANAVERAL, Fla. – NASA Kennedy Space Center Bob Cabana talks to guests at the annual Community Leaders Breakfast held in the Debus Center at Kennedy's Visitor Complex. Community leaders, business executives, educators, community organizers and state and local government heard Cabana provide an overview of operations at the space center and a look ahead at upcoming missions and activities. Photo credit: NASA/Kim Shiflett

  7. KSC-04pd1884

    NASA Image and Video Library

    2004-09-22

    KENNEDY SPACE CENTER, FLA. - In the Reusable Launch Vehicle (RLV) Hangar, workers begin wrapping racks of equipment in preparation for the arrival of Hurricane Jeanne, expected to impact Central Florida Sunday. This is the fourth hurricane in 45 days to make landfall somewhere in the state. The Thermal Protection System (TPS) Facility suffered extensive damage from Hurricane Frances, causing the relocation of equipment to the RLV.

  8. Kepler Media Briefing

    NASA Image and Video Library

    2009-02-19

    Debra Fischer, a professor of Astronomy at San Francisco State University, talks about the Kepler mission during a media briefing, Thursday, Feb. 19, 2008, at NASA Headquarters in Washington. Kepler, the first mission with the ability to find planets like earth, is scheduled to launch on March 5, 2009 from Cape Canaveral Air Force Station, Fla. aboard a Delta II rocket. Photo Credit: (NASA/Paul. E. Alers)

  9. KSC-03PD-1454

    NASA Technical Reports Server (NTRS)

    2003-01-01

    KENNEDY SPACE CENTER, FLA. - Valerie Cassanto, with Instrumentation Technology Associates, Inc., and Bob McLean, from the Southwest Texas State University, work on an experiment found during the search for Columbia debris. Included in the Commercial ITA Biomedical Experiments payload on mission STS-107 are urokinase cancer research, microencapsulation of drugs, the Growth of Bacterial Biofilm on Surfaces during Spaceflight (GOBBSS), and tin crystal formation.

  10. KSC-04pd1921

    NASA Image and Video Library

    2004-09-27

    KENNEDY SPACE CENTER, FLA. - In the Orbiter Processing Facility, the wing of the orbiter Atlantis is covered in plastic, part of the preparation to protect the vehicles from possible damage by Hurricane Jeanne. The storm ravaged Central Florida for 21 hours as it crossed the shoreline on the east coast Sept. 25-26. Hurricane Jeanne was the fourth hurricane in 6 weeks to batter the state.

  11. KSC-04pd1920

    NASA Image and Video Library

    2004-09-27

    KENNEDY SPACE CENTER, FLA. - In the Orbiter Processing Facility, the nose of orbiter Atlantis is covered in plastic, part of the preparation to protect the vehicles from possible damage by Hurricane Jeanne. The storm ravaged Central Florida for 21 hours as it crossed the shoreline on the east coast Sept. 25-26. Hurricane Jeanne was the fourth hurricane in 6 weeks to batter the state.

  12. KENNEDY SPACE CENTER, FLA. - Arturo Ramierez, Charles Curley and Duke Follistein, KSC and Costa Rican researchers, carry the hazardous gas detection system AVEMS to the central of the Turrialba volcano. The Aircraft-based Volcanic Emission Mass Spectrometer determines the presence and concentration of various chemicals. It is being tested in flights over the Turrialba volcano and in the crater, sampling and analyzing fresh volcanic gases in their natural chemical state. The AVEMS system has been developed for use in the Space Shuttle program, to detect toxic gas leaks and emissions in the Shuttle’s aft compartment and the crew compartment.

    NASA Image and Video Library

    2003-03-31

    KENNEDY SPACE CENTER, FLA. - Arturo Ramierez, Charles Curley and Duke Follistein, KSC and Costa Rican researchers, carry the hazardous gas detection system AVEMS to the central of the Turrialba volcano. The Aircraft-based Volcanic Emission Mass Spectrometer determines the presence and concentration of various chemicals. It is being tested in flights over the Turrialba volcano and in the crater, sampling and analyzing fresh volcanic gases in their natural chemical state. The AVEMS system has been developed for use in the Space Shuttle program, to detect toxic gas leaks and emissions in the Shuttle’s aft compartment and the crew compartment.

  13. Environmental factors shaping cultured free-living amoebae and their associated bacterial community within drinking water network.

    PubMed

    Delafont, Vincent; Bouchon, Didier; Héchard, Yann; Moulin, Laurent

    2016-09-01

    Free-living amoebae (FLA) constitute an important part of eukaryotic populations colonising drinking water networks. However, little is known about the factors influencing their ecology in such environments. Because of their status as reservoir of potentially pathogenic bacteria, understanding environmental factors impacting FLA populations and their associated bacterial community is crucial. Through sampling of a large drinking water network, the diversity of cultivable FLA and their bacterial community were investigated by an amplicon sequencing approach, and their correlation with physicochemical parameters was studied. While FLA ubiquitously colonised the water network all year long, significant changes in population composition were observed. These changes were partially explained by several environmental parameters, namely water origin, temperature, pH and chlorine concentration. The characterisation of FLA associated bacterial community reflected a diverse but rather stable consortium composed of nearly 1400 OTUs. The definition of a core community highlighted the predominance of only few genera, majorly dominated by Pseudomonas and Stenotrophomonas. Co-occurrence analysis also showed significant patterns of FLA-bacteria association, and allowed uncovering potentially new FLA - bacteria interactions. From our knowledge, this study is the first that combines a large sampling scheme with high-throughput identification of FLA together with associated bacteria, along with their influencing environmental parameters. Our results demonstrate the importance of physicochemical parameters in the ecology of FLA and their bacterial community in water networks. Copyright © 2016 Elsevier Ltd. All rights reserved.

  14. Antisense expression of the fasciclin-like arabinogalactan protein FLA6 gene in Populus inhibits expression of its homologous genes and alters stem biomechanics and cell wall composition in transgenic trees

    PubMed Central

    Wang, Haihai; Jiang, Chunmei; Wang, Cuiting; Yang, Yang; Yang, Lei; Gao, Xiaoyan; Zhang, Hongxia

    2015-01-01

    Fasciclin-like arabinogalactan proteins (FLAs) play important roles in the growth and development of roots, stems, and seeds in Arabidopsis. However, their biological functions in woody plants are largely unknown. In this work, we investigated the possible function of PtFLA6 in poplar. Quantitative real-time PCR, PtFLA6–yellow fluorescent protein (YFP) fusion protein subcellular localization, Western blotting, and immunohistochemical analyses demonstrated that the PtFLA6 gene was expressed specifically in the xylem of mature stem, and PtFLA6 protein was distributed ubiquitous in plant cells and accumulated predominantly in stem xylem fibres. Antisense expression of PtFLA6 in the aspen hybrid clone Poplar davidiana×Poplar bolleana reduced the transcripts of PtFLA6 and its homologous genes. Transgenic plants that showed a significant reduction in the transcripts of PtFLAs accumulated fewer PtFLA6 and arabinogalactan proteins than did the non-transgenic plants, leading to reduced stem flexural strength and stiffness. Further studies revealed that the altered stem biomechanics of transgenic plants could be attributed to the decreased cellulose and lignin composition in the xylem. In addition expression of some xylem-specific genes involved in cell wall biosynthesis was downregulated in these transgenic plants. All these results suggest that engineering the expression of PtFLA6 and its homologues could modulate stem mechanical properties by affecting cell wall composition in trees. PMID:25428999

  15. Recombinant Mip-PilE-FlaA dominant epitopes vaccine candidate against Legionella pneumophila.

    PubMed

    He, Jinlei; Huang, Fan; Chen, Han; Chen, Qiwei; Zhang, Junrong; Li, Jiao; Chen, Dali; Chen, Jianping

    2017-06-01

    Legionella pneumophila is the main causative agent of Legionnaires' disease, which is a severe multi-system disease with pneumonia as the primary manifestation. We designed a recombinant Mip-PilE-FlaA dominant epitopes vaccine against Legionella pneumophila to prevent the disease and evaluated its immunogenicity and protective immunity. The protein structures of Mip, PilE and FlaA were analyzed using a computer, and the gene sequences of the dominant epitopes of the three proteins were selected to construct and optimize the vaccine. The optimized mip, pilE, flaA and recombinant mip-pilE-flaA gene sequences were cloned, expressed and purified. The purified proteins were used as dominant epitopes vaccines to immunize BALB/c mice and determine the protective immunity and immunogenicity of these purified proteins. The identification confirmed that the recombinant mip-pilE-flaA was successfully cloned and expressed. ELISA revealed that the Mip-PilE-FlaA group produced the highest IgG response, and this protein may considerably improve the production of some cytokines in BALB/c mice. Histopathology analyses of lungs from mice immunized with Mip-PilE-FlaA revealed a certain protective effect. Our work demonstrated that the recombinant dominant epitopes of Mip-PilE-FlaA exhibited strong immunogenicity and immune protection, and this protein may be an efficient epitopes vaccine candidate against Legionella pneumophila. Copyright © 2017 European Federation of Immunological Societies. Published by Elsevier B.V. All rights reserved.

  16. KSC-2009-2584

    NASA Image and Video Library

    2009-03-22

    CAPE CANAVERAL, Fla. – In the Astrotech payload processing facility in Titusville, Fla., technicians monitor the alignment of the GOES-O satellite onto a special stand for loading of its oxidizer and hydrazine propellants. The latest Geostationary Operational Environmental Satellite, GOES-O was developed by NASA for the National Oceanic and Atmospheric Administration, or NOAA. The GOES satellites continuously provide observations of 60 percent of the Earth including the continental United States, providing weather monitoring and forecast operations as well as a continuous and reliable stream of environmental information and severe weather warnings. Once in orbit, GOES-O will be designated GOES-14, and NASA will provide on-orbit checkout and then transfer operational responsibility to NOAA. The GOES-O satellite is targeted to launch from Cape Canaveral Air Force Station's Launch Complex 37 no earlier than May 12 onboard a United Launch Alliance Delta IV expendable launch vehicle. Photo credit: NASA/Troy Cryder

  17. KSC-2009-2585

    NASA Image and Video Library

    2009-03-22

    CAPE CANAVERAL, Fla. – In the Astrotech payload processing facility in Titusville, Fla., technicians check the alignment of the GOES-O satellite onto a special stand for loading of its oxidizer and hydrazine propellants. The latest Geostationary Operational Environmental Satellite, GOES-O was developed by NASA for the National Oceanic and Atmospheric Administration, or NOAA. The GOES satellites continuously provide observations of 60 percent of the Earth including the continental United States, providing weather monitoring and forecast operations as well as a continuous and reliable stream of environmental information and severe weather warnings. Once in orbit, GOES-O will be designated GOES-14, and NASA will provide on-orbit checkout and then transfer operational responsibility to NOAA. The GOES-O satellite is targeted to launch from Cape Canaveral Air Force Station's Launch Complex 37 no earlier than May 12 onboard a United Launch Alliance Delta IV expendable launch vehicle. Photo credit: NASA/Troy Cryder

  18. Occurrence of Infected Free-Living Amoebae in Cooling Towers of Southern Brazil.

    PubMed

    Soares, Scheila S; Souza, Thamires K; Berté, Francisco K; Cantarelli, Vlademir V; Rott, Marilise B

    2017-12-01

    This study determined the occurrence of potentially pathogenic free-living amoebae (FLA) and bacteria associated with amoebae in air-conditioning cooling towers in southern Brazil. Water samples were collected from 36 cooling systems from air-conditioning in the state of Rio Grande do Sul, Brazil. The organisms were identified using polymerase chain reaction (PCR) and sequencing automated. The results showed that these aquatic environments, with variable temperature, are potential "hot spots" for emerging human pathogens like free-living amoebae and bacteria associated. In total, 92% of the cooling-tower samples analyzed were positive for FLA, and Acanthamoeba was the dominant genus by culture and PCR. Amoebal isolates revealed intracellular bacteria in 39.3% of them and all were confirmed as members of the genus Pseudomonas. The results obtained show the important role of cooling towers as a source of amoebae-associated pathogens.

  19. KSC-2009-2587

    NASA Image and Video Library

    2009-03-22

    CAPE CANAVERAL, Fla. – In the Astrotech payload processing facility in Titusville, Fla., technicians secure the GOES-O satellite onto a special stand for loading of its oxidizer and hydrazine propellants. The latest Geostationary Operational Environmental Satellite, GOES-O was developed by NASA for the National Oceanic and Atmospheric Administration, or NOAA. The GOES satellites continuously provide observations of 60 percent of the Earth including the continental United States, providing weather monitoring and forecast operations as well as a continuous and reliable stream of environmental information and severe weather warnings. Once in orbit, GOES-O will be designated GOES-14, and NASA will provide on-orbit checkout and then transfer operational responsibility to NOAA. The GOES-O satellite is targeted to launch from Cape Canaveral Air Force Station's Launch Complex 37 no earlier than May 12 onboard a United Launch Alliance Delta IV expendable launch vehicle. Photo credit: NASA/Troy Cryder

  20. KSC-2009-2577

    NASA Image and Video Library

    2009-03-22

    CAPE CANAVERAL, Fla. – In the Astrotech payload processing facility in Titusville, Fla., technicians lift the GOES-O satellite to move it to a special stand for loading of its oxidizer and hydrazine propellants. The latest Geostationary Operational Environmental Satellite, GOES-O was developed by NASA for the National Oceanic and Atmospheric Administration, or NOAA. The GOES satellites continuously provide observations of 60 percent of the Earth including the continental United States, providing weather monitoring and forecast operations as well as a continuous and reliable stream of environmental information and severe weather warnings. Once in orbit, GOES-O will be designated GOES-14, and NASA will provide on-orbit checkout and then transfer operational responsibility to NOAA. The GOES-O satellite is targeted to launch from Cape Canaveral Air Force Station's Launch Complex 37 no earlier than May 12 onboard a United Launch Alliance Delta IV expendable launch vehicle. Photo credit: NASA/Troy Cryder

  1. KSC-2009-2581

    NASA Image and Video Library

    2009-03-22

    CAPE CANAVERAL, Fla. – In the Astrotech payload processing facility in Titusville, Fla., the GOES-O satellite traverses the clean room toward a special stand for loading of its oxidizer and hydrazine propellants. The latest Geostationary Operational Environmental Satellite, GOES-O was developed by NASA for the National Oceanic and Atmospheric Administration, or NOAA. The GOES satellites continuously provide observations of 60 percent of the Earth including the continental United States, providing weather monitoring and forecast operations as well as a continuous and reliable stream of environmental information and severe weather warnings. Once in orbit, GOES-O will be designated GOES-14, and NASA will provide on-orbit checkout and then transfer operational responsibility to NOAA. The GOES-O satellite is targeted to launch from Cape Canaveral Air Force Station's Launch Complex 37 no earlier than May 12 onboard a United Launch Alliance Delta IV expendable launch vehicle. Photo credit: NASA/Troy Cryder

  2. KSC-2009-2580

    NASA Image and Video Library

    2009-03-22

    CAPE CANAVERAL, Fla. – In the Astrotech payload processing facility in Titusville, Fla., the GOES-O satellite is moved toward a special stand for loading of its oxidizer and hydrazine propellants. The latest Geostationary Operational Environmental Satellite, GOES-O was developed by NASA for the National Oceanic and Atmospheric Administration, or NOAA. The GOES satellites continuously provide observations of 60 percent of the Earth including the continental United States, providing weather monitoring and forecast operations as well as a continuous and reliable stream of environmental information and severe weather warnings. Once in orbit, GOES-O will be designated GOES-14, and NASA will provide on-orbit checkout and then transfer operational responsibility to NOAA. The GOES-O satellite is targeted to launch from Cape Canaveral Air Force Station's Launch Complex 37 no earlier than May 12 onboard a United Launch Alliance Delta IV expendable launch vehicle. Photo credit: NASA/Troy Cryder

  3. KSC-2009-2582

    NASA Image and Video Library

    2009-03-22

    CAPE CANAVERAL, Fla. – In the Astrotech payload processing facility in Titusville, Fla., the GOES-O satellite is gently moved toward a special stand for loading of its oxidizer and hydrazine propellants. The latest Geostationary Operational Environmental Satellite, GOES-O was developed by NASA for the National Oceanic and Atmospheric Administration, or NOAA. The GOES satellites continuously provide observations of 60 percent of the Earth including the continental United States, providing weather monitoring and forecast operations as well as a continuous and reliable stream of environmental information and severe weather warnings. Once in orbit, GOES-O will be designated GOES-14, and NASA will provide on-orbit checkout and then transfer operational responsibility to NOAA. The GOES-O satellite is targeted to launch from Cape Canaveral Air Force Station's Launch Complex 37 no earlier than May 12 onboard a United Launch Alliance Delta IV expendable launch vehicle. Photo credit: NASA/Troy Cryder

  4. KSC-2009-2583

    NASA Image and Video Library

    2009-03-22

    CAPE CANAVERAL, Fla. – In the Astrotech payload processing facility in Titusville, Fla., the GOES-O satellite is gently lowered onto a special stand for loading of its oxidizer and hydrazine propellants. The latest Geostationary Operational Environmental Satellite, GOES-O was developed by NASA for the National Oceanic and Atmospheric Administration, or NOAA. The GOES satellites continuously provide observations of 60 percent of the Earth including the continental United States, providing weather monitoring and forecast operations as well as a continuous and reliable stream of environmental information and severe weather warnings. Once in orbit, GOES-O will be designated GOES-14, and NASA will provide on-orbit checkout and then transfer operational responsibility to NOAA. The GOES-O satellite is targeted to launch from Cape Canaveral Air Force Station's Launch Complex 37 no earlier than May 12 onboard a United Launch Alliance Delta IV expendable launch vehicle. Photo credit: NASA/Troy Cryder

  5. KSC-2009-2588

    NASA Image and Video Library

    2009-03-22

    CAPE CANAVERAL, Fla. – In the Astrotech payload processing facility in Titusville, Fla., technicians secure the GOES-O satellite onto a special stand for loading of its oxidizer and hydrazine propellants. The latest Geostationary Operational Environmental Satellite, GOES-O was developed by NASA for the National Oceanic and Atmospheric Administration, or NOAA. The GOES satellites continuously provide observations of 60 percent of the Earth including the continental United States, providing weather monitoring and forecast operations as well as a continuous and reliable stream of environmental information and severe weather warnings. Once in orbit, GOES-O will be designated GOES-14, and NASA will provide on-orbit checkout and then transfer operational responsibility to NOAA. The GOES-O satellite is targeted to launch from Cape Canaveral Air Force Station's Launch Complex 37 no earlier than May 12 onboard a United Launch Alliance Delta IV expendable launch vehicle. Photo credit: NASA/Troy Cryder

  6. KSC-2009-2576

    NASA Image and Video Library

    2009-03-22

    CAPE CANAVERAL, Fla. – In the Astrotech payload processing facility in Titusville, Fla., technicians prepare to move the GOES-O satellite onto a special stand for loading of its oxidizer and hydrazine propellants. The latest Geostationary Operational Environmental Satellite, GOES-O was developed by NASA for the National Oceanic and Atmospheric Administration, or NOAA. The GOES satellites continuously provide observations of 60 percent of the Earth including the continental United States, providing weather monitoring and forecast operations as well as a continuous and reliable stream of environmental information and severe weather warnings. Once in orbit, GOES-O will be designated GOES-14, and NASA will provide on-orbit checkout and then transfer operational responsibility to NOAA. The GOES-O satellite is targeted to launch from Cape Canaveral Air Force Station's Launch Complex 37 no earlier than May 12 onboard a United Launch Alliance Delta IV expendable launch vehicle. Photo credit: NASA/Troy Cryder

  7. KSC-2009-2578

    NASA Image and Video Library

    2009-03-22

    CAPE CANAVERAL, Fla. – In the Astrotech payload processing facility in Titusville, Fla., technicians move the GOES-O satellite toward a special stand for loading of its oxidizer and hydrazine propellants. The latest Geostationary Operational Environmental Satellite, GOES-O was developed by NASA for the National Oceanic and Atmospheric Administration, or NOAA. The GOES satellites continuously provide observations of 60 percent of the Earth including the continental United States, providing weather monitoring and forecast operations as well as a continuous and reliable stream of environmental information and severe weather warnings. Once in orbit, GOES-O will be designated GOES-14, and NASA will provide on-orbit checkout and then transfer operational responsibility to NOAA. The GOES-O satellite is targeted to launch from Cape Canaveral Air Force Station's Launch Complex 37 no earlier than May 12 onboard a United Launch Alliance Delta IV expendable launch vehicle. Photo credit: NASA/Troy Cryder

  8. KSC-2009-2579

    NASA Image and Video Library

    2009-03-22

    CAPE CANAVERAL, Fla. – In the Astrotech payload processing facility in Titusville, Fla., technicians monitor the lift of the GOES-O satellite toward a special stand for loading of its oxidizer and hydrazine propellants. The latest Geostationary Operational Environmental Satellite, GOES-O was developed by NASA for the National Oceanic and Atmospheric Administration, or NOAA. The GOES satellites continuously provide observations of 60 percent of the Earth including the continental United States, providing weather monitoring and forecast operations as well as a continuous and reliable stream of environmental information and severe weather warnings. Once in orbit, GOES-O will be designated GOES-14, and NASA will provide on-orbit checkout and then transfer operational responsibility to NOAA. The GOES-O satellite is targeted to launch from Cape Canaveral Air Force Station's Launch Complex 37 no earlier than May 12 onboard a United Launch Alliance Delta IV expendable launch vehicle. Photo credit: NASA/Troy Cryder

  9. KSC-2009-3556

    NASA Image and Video Library

    2009-06-05

    CAPE CANAVERAL, Fla. – At the Astrotech payload processing facility in Titusville, Fla., workers prepare to move the platform on which the encapsulated GOES-O satellite sits in preparation for moving GOES-O to Cape Canaveral Air Force Station's Launch Complex 37 pad where it will be mated with the United Launch Alliance Delta IV expendable launch vehicle. The GOES-O satellite is targeted to launch no earlier than June 26. The latest Geostationary Operational Environmental Satellite, GOES-O was developed by NASA for the National Oceanic and Atmospheric Administration, or NOAA. The GOES satellites continuously provide observations of 60 percent of the Earth including the continental United States, providing weather monitoring and forecast operations as well as a continuous and reliable stream of environmental information and severe weather warnings. Once in orbit, GOES-O will be designated GOES-14, and NASA will provide on-orbit checkout and then transfer operational responsibility to NOAA. Photo credit: NASA/Jack Pfaller

  10. KSC-2009-3557

    NASA Image and Video Library

    2009-06-05

    CAPE CANAVERAL, Fla. – At the Astrotech payload processing facility in Titusville, Fla., workers move the platform on which the encapsulated GOES-O satellite sits in preparation for moving GOES-O to Cape Canaveral Air Force Station's Launch Complex 37 pad where it will be mated with the United Launch Alliance Delta IV expendable launch vehicle. The GOES-O satellite is targeted to launch no earlier than June 26. The latest Geostationary Operational Environmental Satellite, GOES-O was developed by NASA for the National Oceanic and Atmospheric Administration, or NOAA. The GOES satellites continuously provide observations of 60 percent of the Earth including the continental United States, providing weather monitoring and forecast operations as well as a continuous and reliable stream of environmental information and severe weather warnings. Once in orbit, GOES-O will be designated GOES-14, and NASA will provide on-orbit checkout and then transfer operational responsibility to NOAA. Photo credit: NASA/Jack Pfaller

  11. KSC-2009-3554

    NASA Image and Video Library

    2009-06-05

    CAPE CANAVERAL, Fla. – At the Astrotech payload processing facility in Titusville, Fla., access platforms are being removed from around the encapsulated GOES-O satellite in preparation for moving GOES-O to Cape Canaveral Air Force Station's Launch Complex 37 pad where it will be mated with the United Launch Alliance Delta IV expendable launch vehicle. The GOES-O satellite is targeted to launch no earlier than June 26. The latest Geostationary Operational Environmental Satellite, GOES-O was developed by NASA for the National Oceanic and Atmospheric Administration, or NOAA. The GOES satellites continuously provide observations of 60 percent of the Earth including the continental United States, providing weather monitoring and forecast operations as well as a continuous and reliable stream of environmental information and severe weather warnings. Once in orbit, GOES-O will be designated GOES-14, and NASA will provide on-orbit checkout and then transfer operational responsibility to NOAA. Photo credit: NASA/Jack Pfaller

  12. KSC-2009-3555

    NASA Image and Video Library

    2009-06-05

    CAPE CANAVERAL, Fla. – At the Astrotech payload processing facility in Titusville, Fla., access platforms are being removed from around the encapsulated GOES-O satellite in preparation for moving GOES-O to Cape Canaveral Air Force Station's Launch Complex 37 pad where it will be mated with the United Launch Alliance Delta IV expendable launch vehicle. The GOES-O satellite is targeted to launch no earlier than June 26. The latest Geostationary Operational Environmental Satellite, GOES-O was developed by NASA for the National Oceanic and Atmospheric Administration, or NOAA. The GOES satellites continuously provide observations of 60 percent of the Earth including the continental United States, providing weather monitoring and forecast operations as well as a continuous and reliable stream of environmental information and severe weather warnings. Once in orbit, GOES-O will be designated GOES-14, and NASA will provide on-orbit checkout and then transfer operational responsibility to NOAA. Photo credit: NASA/Jack Pfaller

  13. KSC-2009-3558

    NASA Image and Video Library

    2009-06-05

    CAPE CANAVERAL, Fla. – At the Astrotech payload processing facility in Titusville, Fla., workers move the platform on which the encapsulated GOES-O satellite sits in preparation for moving GOES-O to Cape Canaveral Air Force Station's Launch Complex 37 pad where it will be mated with the United Launch Alliance Delta IV expendable launch vehicle. The GOES-O satellite is targeted to launch no earlier than June 26. The latest Geostationary Operational Environmental Satellite, GOES-O was developed by NASA for the National Oceanic and Atmospheric Administration, or NOAA. The GOES satellites continuously provide observations of 60 percent of the Earth including the continental United States, providing weather monitoring and forecast operations as well as a continuous and reliable stream of environmental information and severe weather warnings. Once in orbit, GOES-O will be designated GOES-14, and NASA will provide on-orbit checkout and then transfer operational responsibility to NOAA. Photo credit: NASA/Jack Pfaller

  14. KSC-2009-3842

    NASA Image and Video Library

    2009-06-25

    CAPE CANAVERAL, Fla. – Bart Hagemeyer, at left, meteorologist in charge, NOAA National Weather Service forecast office, Melbourne, Fla., and Joel Tumbiolo, Delta IV launch weather officer, 45th Weather Squadron, Cape Canaveral Air Force Station, participate in a prelaunch news conference on the Geostationary Operational Environmental Satellite-O mission in NASA's Kennedy Space Center press site auditorium. The GOES-O satellite is targeted to launch June 26. The latest Geostationary Operational Environmental Satellite, GOES-O was developed by NASA for the National Oceanic and Atmospheric Administration, or NOAA. Each of the GOES satellites continuously provides observations of 60 percent of the Earth including the continental United States, providing weather monitoring and forecast operations as well as a continuous and reliable stream of environmental information and severe weather warnings. Once in orbit, GOES-O will be designated GOES-14, and NASA will provide on-orbit checkout and then transfer operational responsibility to NOAA. Photo credit: NASA/Jim Grossmann

  15. KSC-2011-1628

    NASA Image and Video Library

    2011-02-24

    CAPE CANAVERAL, Fla. -- Folks from across the country camped out in communities surrounding NASA's Kennedy Space Center in Florida to witness space shuttle Discovery make history by lifting off on its final scheduled mission from Launch Pad 39A. Seen here, is State Road 406, also known as the A. Max Brewer Causeway, in Titusville, Fla. Liftoff is set for 4:50 p.m. EST on Feb. 24. Discovery and its six-member STS-133 crew will deliver the Permanent Multipurpose Module, packed with supplies and critical spare parts, as well as Robonaut 2, the dexterous humanoid astronaut helper, to the International Space Station. Discovery, which will fly its 39th mission, is scheduled to be retired following STS-133. This will be the 133rd Space Shuttle Program mission and the 35th shuttle voyage to the space station. For more information on the STS-133 mission, visit www.nasa.gov/mission_pages/shuttle/shuttlemissions/sts133/. Photo credit: NASA/Jack Pfaller

  16. KSC-2011-1630

    NASA Image and Video Library

    2011-02-24

    CAPE CANAVERAL, Fla. -- Folks from across the country camped out in communities surrounding NASA's Kennedy Space Center in Florida to witness space shuttle Discovery make history by lifting off on its final scheduled mission from Launch Pad 39A. Seen here, is State Road 406, also known as the A. Max Brewer Causeway, in Titusville, Fla. Liftoff is set for 4:50 p.m. EST on Feb. 24. Discovery and its six-member STS-133 crew will deliver the Permanent Multipurpose Module, packed with supplies and critical spare parts, as well as Robonaut 2, the dexterous humanoid astronaut helper, to the International Space Station. Discovery, which will fly its 39th mission, is scheduled to be retired following STS-133. This will be the 133rd Space Shuttle Program mission and the 35th shuttle voyage to the space station. For more information on the STS-133 mission, visit www.nasa.gov/mission_pages/shuttle/shuttlemissions/sts133/. Photo credit: NASA/Jack Pfaller

  17. KSC-2011-1627

    NASA Image and Video Library

    2011-02-24

    CAPE CANAVERAL, Fla. -- Folks from across the country camped out in communities surrounding NASA's Kennedy Space Center in Florida to witness space shuttle Discovery make history by lifting off on its final scheduled mission from Launch Pad 39A. Seen here, is State Road 406, also known as the A. Max Brewer Causeway, in Titusville, Fla. Liftoff is set for 4:50 p.m. EST on Feb. 24. Discovery and its six-member STS-133 crew will deliver the Permanent Multipurpose Module, packed with supplies and critical spare parts, as well as Robonaut 2, the dexterous humanoid astronaut helper, to the International Space Station. Discovery, which will fly its 39th mission, is scheduled to be retired following STS-133. This will be the 133rd Space Shuttle Program mission and the 35th shuttle voyage to the space station. For more information on the STS-133 mission, visit www.nasa.gov/mission_pages/shuttle/shuttlemissions/sts133/. Photo credit: NASA/Jack Pfaller

  18. A systematic review of filler agents for aesthetic treatment of HIV facial lipoatrophy (FLA).

    PubMed

    Jagdeo, Jared; Ho, Derek; Lo, Alex; Carruthers, Alastair

    2015-12-01

    HIV facial lipoatrophy (FLA) is characterized by facial volume loss. HIV FLA affects the facial contours of the cheeks, temples, and orbits, and is associated with social stigma. Although new highly active antiretroviral therapy medications are associated with less severe FLA, the prevalence of HIV FLA among treated individuals exceeds 50%. The goal of our systematic review is to examine published clinical studies involving the use of filler agents for aesthetic treatment of HIV FLA and to provide evidence-based recommendations based on published efficacy and safety data. A systematic review of the published literature was performed on July 1, 2015, on filler agents for aesthetic treatment of HIV FLA. Based on published studies, poly-L-lactic acid is the only filler agent with grade of recommendation: B. Other reviewed filler agents received grade of recommendation: C or D. Poly-L-lactic acid may be best for treatment over temples and cheeks, whereas calcium hydroxylapatite, with a Food and Drug Administration indication of subdermal implantation, may be best used deeply over bone for focal enhancement. Additional long-term randomized controlled trials are necessary to elucidate the advantages and disadvantages of fillers that have different biophysical properties, in conjunction with cost-effectiveness analysis, for treatment of HIV FLA. Published by Elsevier Inc.

  19. KSC-04PD-0769

    NASA Technical Reports Server (NTRS)

    2004-01-01

    KENNEDY SPACE CENTER, FLA. -- From left, Florida Gov. Jeb Bush, U.S. Mint Director Henrietta Holsman Fore, Deputy Secretary of the Treasury Samuel W. Bodman, and NASA Administrator Sean OKeefe participate in the launching ceremony for the new Florida quarter, held at the KSC Visitor Complex. In the background is a map of the United States illustrating the state quarters issued to date. The newly unveiled quarter celebrates Florida as the gateway to discovery -- a destination for explorers in the past, a launch site for space explorers of the future, and an inviting place for visitors today.

  20. KSC-04pd0769

    NASA Image and Video Library

    2004-04-07

    KENNEDY SPACE CENTER, FLA. -- From left, Florida Gov. Jeb Bush, U.S. Mint Director Henrietta Holsman Fore, Deputy Secretary of the Treasury Samuel W. Bodman, and NASA Administrator Sean O’Keefe participate in the launching ceremony for the new Florida quarter, held at the KSC Visitor Complex. In the background is a map of the United States illustrating the state quarters issued to date. The newly unveiled quarter celebrates Florida as the gateway to discovery -- a destination for explorers in the past, a launch site for space explorers of the future, and an inviting place for visitors today.

  1. 78 FR 11272 - Submission for OMB Review; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-15

    ... and Budget, Attention: Desk Officer for Treasury, New Executive Office Building, Room 10235... for Spin-Off Rulings. Abstract: This revenue procedure updates Rev. Proc. 96-30, which sets forth in a...

  2. Spitzer Telemetry Processing System

    NASA Technical Reports Server (NTRS)

    Stanboli, Alice; Martinez, Elmain M.; McAuley, James M.

    2013-01-01

    The Spitzer Telemetry Processing System (SirtfTlmProc) was designed to address objectives of JPL's Multi-mission Image Processing Lab (MIPL) in processing spacecraft telemetry and distributing the resulting data to the science community. To minimize costs and maximize operability, the software design focused on automated error recovery, performance, and information management. The system processes telemetry from the Spitzer spacecraft and delivers Level 0 products to the Spitzer Science Center. SirtfTlmProc is a unique system with automated error notification and recovery, with a real-time continuous service that can go quiescent after periods of inactivity. The software can process 2 GB of telemetry and deliver Level 0 science products to the end user in four hours. It provides analysis tools so the operator can manage the system and troubleshoot problems. It automates telemetry processing in order to reduce staffing costs.

  3. Fixed point theorems for generalized contractions in ordered metric spaces

    NASA Astrophysics Data System (ADS)

    O'Regan, Donal; Petrusel, Adrian

    2008-05-01

    The purpose of this paper is to present some fixed point results for self-generalized contractions in ordered metric spaces. Our results generalize and extend some recent results of A.C.M. Ran, M.C. Reurings [A.C.M. Ran, MEC. Reurings, A fixed point theorem in partially ordered sets and some applications to matrix equations, Proc. Amer. Math. Soc. 132 (2004) 1435-1443], J.J. Nieto, R. Rodríguez-López [J.J. Nieto, R. Rodríguez-López, Contractive mapping theorems in partially ordered sets and applications to ordinary differential equations, Order 22 (2005) 223-239; J.J. Nieto, R. Rodríguez-López, Existence and uniqueness of fixed points in partially ordered sets and applications to ordinary differential equations, Acta Math. Sin. (Engl. Ser.) 23 (2007) 2205-2212], J.J. Nieto, R.L. Pouso, R. Rodríguez-López [J.J. Nieto, R.L. Pouso, R. Rodríguez-López, Fixed point theorem theorems in ordered abstract sets, Proc. Amer. Math. Soc. 135 (2007) 2505-2517], A. Petrusel, I.A. Rus [A. Petrusel, I.A. Rus, Fixed point theorems in ordered L-spaces, Proc. Amer. Math. Soc. 134 (2006) 411-418] and R.P. Agarwal, M.A. El-Gebeily, D. O'Regan [R.P. Agarwal, M.A. El-Gebeily, D. O'Regan, Generalized contractions in partially ordered metric spaces, Appl. Anal., in press]. As applications, existence and uniqueness results for Fredholm and Volterra type integral equations are given.

  4. The Second Great Thermal Event from the History of the Solar System as Origin of the Lunar Asymmetries and Paleomagnetism

    NASA Astrophysics Data System (ADS)

    Neagu, A.

    1993-07-01

    To explain the origin of the natural remanent magnetism (NRM) of lunar rocks [1,2] and lunar asymmetries [3-5], many models suppose an asymmetric arrangement of matter within the early Moon [6,7]. Presented here is a model of lunar evolution that explains both the appearance of the lunar asymmetries and the presence of a high lunar palaeomagnetic field in the vicinity of 3.9 Ga starting from a symmetrically differentiated Moon. According to this model, less than 0.2 Ga after its formation as a completely molten planetary body, the Moon differentiated in concentric layers to form an anorthositic crust, a mantle, and an iron core [8]. Lunar asymmetries appeared at about 3.9 Ga ago when the Sun underwent a very violent explosive phase, generating the second great thermal event (SGTE) from the history of the solar system. Solar plasma into expansion interacted with the solar system bodies, erasing previous records on a large part of their surfaces and generating thermal effects of various kinds. Figure 1 presents the manner in which the solar plasma "excavated" within the lunar crust. The result was the displacement of the lunar center-of-figure (CF) and center-of mass (CM) from O in their present positions [3-5]. A similar "excavation" within the primordial crust of the Earth generated the appearance of a protocontinental land (Proto-Pangaea). Eccentric placement of the lunar core immediately after SGTE occurrence and its movement toward the new position of the lunar CM, along with change of the lunar spin into a synchronous rotation, generated lunar internal motions vigorously enough to drive lunar dynamo. Figure 2 presents the lunar palaeomagnetic field intensity as a function of time according to this scenario. Immediately after SGTE occurrence, the lunar crust was subjected to intensive bombardment with impacting masses belonging to Population II impactors [9]. The larger impacts generated zones of weakness and fissures within the lunar crust, but the isostatic answer of the lunar interior and its asymmetric structure permitted mare volcanism to occur only on the nearside [10]. This model is strongly supported by isotopic, petrologic, and magnetic analyses of lunar nearside rocks that give abundant evidence for a widespread thermal metamorphism at about 3.9 Ga. It is reflected especially in partial to complete equilibration of the isotopic systems [8], in the redistribution of volatiles on lunar surface [11-13] and in the thermoremanent magnetization of lunar breccias [14]. This model also explains the asymmetric distribution of the thorium concentrations in the lunar surface [15] and the presence, near the lunar surface, of rocks of deep-seated origin [16]. References: [1] Nagata T. et al. (1970) Proc. Apollo 11 LSC, 2325. [2] Strangway D. W. (1971) EPSL, 13, 43. [3] Kaula W. M. et al. (1972) Proc. LSC 3rd, 2189. [4] Kaula W. M. et al. (1974) Proc. LSC 5th, 3049. [5] Haines E. L. and Metzger A. E. (1980) Proc. LPSC 11th, 689. [6] Stevenson D. J. (1980) Nature, 287, 520. [7] Ransford G. and Sjogren W. (1972) Nature, 238, 260. [8] Wasserburg G. J. et al. (1977) Phil. Trans. R. Soc. Lond., A285, 7. [9] Neagu A. (1993) 18th EGS Meeting, Wiesbaden. [10] Neagu A. (1992) Meteoritics, 27, 267. [11] Tera F. and Wasserburg G. J. (1972) EPSL, 14, 281. [12] Nunes P. D. and Tatsumoto M. (1973) Science, 182, 916. [13] Cirlin E. H. and Housley R. M. (1980) Proc. LPSC 11th, 349. [14] Gose W. A. et al. (1978) EPSL, 38, 373. [15] Metzger A. E. et al. (1977) Proc. LSC 8th, 949. [16] James O. B. (1980) Proc. LPSC 11th, 365. Fig. 1, which appears here in the hard copy, shows a schematic equatorial cross section of the Moon showing the lunar internal structure before and after SGTE occurred. Fig. 2 appears here in the hard copy.

  5. The effects of beta-endorphin: state change modification.

    PubMed

    Veening, Jan G; Barendregt, Henk P

    2015-01-29

    Beta-endorphin (β-END) is an opioid neuropeptide which has an important role in the development of hypotheses concerning the non-synaptic or paracrine communication of brain messages. This kind of communication between neurons has been designated volume transmission (VT) to differentiate it clearly from synaptic communication. VT occurs over short as well as long distances via the extracellular space in the brain, as well as via the cerebrospinal fluid (CSF) flowing through the ventricular spaces inside the brain and the arachnoid space surrounding the central nervous system (CNS). To understand how β-END can have specific behavioral effects, we use the notion behavioral state, inspired by the concept of machine state, coming from Turing (Proc London Math Soc, Series 2,42:230-265, 1937). In section 1.4 the sequential organization of male rat behavior is explained showing that an animal is not free to switch into another state at any given moment. Funneling-constraints restrict the number of possible behavioral transitions in specific phases while at other moments in the sequence the transition to other behavioral states is almost completely open. The effects of β-END on behaviors like food intake and sexual behavior, and the mechanisms involved in reward, meditation and pain control are discussed in detail. The effects on the sequential organization of behavior and on state transitions dominate the description of these effects.

  6. Presence of Legionella and Free-Living Amoebae in Composts and Bioaerosols from Composting Facilities

    PubMed Central

    Conza, Lisa; Pagani, Simona Casati; Gaia, Valeria

    2013-01-01

    Several species of Legionella cause Legionnaires’ disease (LD). Infection may occur through inhalation of Legionella or amoebal vesicles. The reservoirs of Legionella are water, soil, potting soil and compost. Some species of free-living amoebae (FLA) that are naturally present in water and soil were described as hosts for Legionella. This study aimed to understand whether or not the composting facilities could be sources of community-acquired Legionella infections after development of bioaerosols containing Legionella or FLA. We looked for the presence of Legionella (by co-culture) and FLA (by culture) in composts and bioaerosols collected at four composting facilities located in southern Switzerland. We investigated the association between the presence of Legionella and compost and air parameters and presence of FLA. Legionella spp. (including L. pneumophila) were detected in 69.3% (61/88) of the composts and FLA (mainly Acanthamoeba, Vermamoeba, Naegleria and Stenamoeba) in 92.0% (81/88). L. pneumophila and L. bozemanii were most frequently isolated. FLA as potential host for Legionella spp. were isolated from 40.9% (36/88) of the composts in all facilities. In Legionella-positive samples the temperature of compost was significantly lower (P = 0.012) than in Legionella-negative samples. Of 47 bioaerosol samples, 19.1% (9/47) were positive for FLA and 10.6% (5/47) for L. pneumophila. Composts (62.8%) were positive for Legionella and FLA contemporaneously, but both microorganisms were never detected simultaneously in bioaerosols. Compost can release bioaerosol containing FLA or Legionella and could represent a source of infection of community-acquired Legionella infections for workers and nearby residents. PMID:23844174

  7. Antisense expression of the fasciclin-like arabinogalactan protein FLA6 gene in Populus inhibits expression of its homologous genes and alters stem biomechanics and cell wall composition in transgenic trees.

    PubMed

    Wang, Haihai; Jiang, Chunmei; Wang, Cuiting; Yang, Yang; Yang, Lei; Gao, Xiaoyan; Zhang, Hongxia

    2015-03-01

    Fasciclin-like arabinogalactan proteins (FLAs) play important roles in the growth and development of roots, stems, and seeds in Arabidopsis. However, their biological functions in woody plants are largely unknown. In this work, we investigated the possible function of PtFLA6 in poplar. Quantitative real-time PCR, PtFLA6-yellow fluorescent protein (YFP) fusion protein subcellular localization, Western blotting, and immunohistochemical analyses demonstrated that the PtFLA6 gene was expressed specifically in the xylem of mature stem, and PtFLA6 protein was distributed ubiquitous in plant cells and accumulated predominantly in stem xylem fibres. Antisense expression of PtFLA6 in the aspen hybrid clone Poplar davidiana×Poplar bolleana reduced the transcripts of PtFLA6 and its homologous genes. Transgenic plants that showed a significant reduction in the transcripts of PtFLAs accumulated fewer PtFLA6 and arabinogalactan proteins than did the non-transgenic plants, leading to reduced stem flexural strength and stiffness. Further studies revealed that the altered stem biomechanics of transgenic plants could be attributed to the decreased cellulose and lignin composition in the xylem. In addition expression of some xylem-specific genes involved in cell wall biosynthesis was downregulated in these transgenic plants. All these results suggest that engineering the expression of PtFLA6 and its homologues could modulate stem mechanical properties by affecting cell wall composition in trees. © The Author 2014. Published by Oxford University Press on behalf of the Society for Experimental Biology.

  8. Kentucky highway user survey 2004.

    DOT National Transportation Integrated Search

    2004-06-01

    The purpose of this study was to continue the efforts begun in 1997 to monitor Kentucky public opinion regarding the quality of highway systems, including a portion to measure satisfaction with current drivers license and registration renewal proc...

  9. Kentucky highway user survey 2001.

    DOT National Transportation Integrated Search

    2002-04-01

    The purpose of this study was to continue the efforts begun in 1997 to monitor Kentucky public opinion regarding the quality of highway systems, including a portion to measure satisfaction with current drivers license and registration renewal proc...

  10. EVALUATING THE SUSTAINABILITY OF GREEN CHEMISTRIES

    EPA Science Inventory

    The U.S. EPA's National Risk Management Research Laboratory is developing a methodology for the evaluation of reaction chemistries. This methodology, called GREENSCOPE (Gauging Reaction Effectiveness for the ENvironmental Sustainability of Chemistries with a multi-Objective Proc...

  11. Bioanalytical Methods for Food Contaminant Analysis

    EPA Science Inventory

    Foods are complex mixtures of lipids, carbohydrates, proteins, vitamins, organic compounds and other naturally occurring compounds. Sometimes added to this mixture are residues of pesticides, veterinary and human drugs, microbial toxins, preservatives, contaminants from food proc...

  12. 76 FR 55070 - Government-Owned Inventions; Availability for Licensing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-06

    ...). Publications: 1. Robbins JB, et al. Synthesis, characterization, and immunogenicity in mice of Shigella sonnei O-specific oligosaccharide- core-protein conjugates. Proc Natl Acad Sci U S A. 2009 May 12;106(19...

  13. Detection of viable Helicobacter pylori inside free-living amoebae in wastewater and drinking water samples from Eastern Spain.

    PubMed

    Moreno-Mesonero, Laura; Moreno, Yolanda; Alonso, José Luis; Ferrús, M Antonia

    2017-10-01

    Helicobacter pylori is one of the most concerning emerging waterborne pathogens. It has been suggested that it could survive in water inside free-living amoebae (FLA), but nobody has studied this relationship in the environment yet. Thus, we aimed to detect viable H. pylori cells from inside FLA in water samples. Sixty-nine wastewater and 31 drinking water samples were collected. FLA were purified and identified by PCR and sequencing. For exclusively detecting H. pylori inside FLA, samples were exposed to sodium hypochlorite and assayed by specific PMA-qPCR, DVC-FISH and culture. FLA were detected in 38.7% of drinking water and 79.7% of wastewater samples, even after disinfection. In wastewater, Acanthamoeba spp. and members of the family Vahlkampfiidae were identified. In drinking water, Acanthamoeba spp. and Echinamoeba and/or Vermamoeba were present. In 39 (58.2%) FLA-positive samples, H. pylori was detected by PMA-qPCR. After DVC-FISH, 21 (31.3%) samples harboured viable H. pylori internalized cells. H. pylori was cultured from 10 wastewater samples. To our knowledge, this is the first report that demonstrates that H. pylori can survive inside FLA in drinking water and wastewater, strongly supporting the hypothesis that FLA could play an important role in the transmission of H. pylori to humans. © 2017 Society for Applied Microbiology and John Wiley & Sons Ltd.

  14. Tautomeric selectivity of the excited-state lifetime of guanine/cytosine base pairs: The role of electron-driven proton-transfer processes

    PubMed Central

    Sobolewski, Andrzej L.; Domcke, Wolfgang; Hättig, C.

    2005-01-01

    The UV spectra of three different conformers of the guanine/cytosine base pair were recorded recently with UV-IR double-resonance techniques in a supersonic jet [Abo-Riziq, A., Grace, L., Nir, E., Kabelac, M., Hobza, P. & de Vries, M. S. (2005) Proc. Natl. Acad. Sci. USA 102, 20–23]. The spectra provide evidence for a very efficient excited-state deactivation mechanism that is specific for the Watson–Crick structure and may be essential for the photostability of DNA. Here we report results of ab initio electronic-structure calculations for the excited electronic states of the three lowest-energy conformers of the guanine/cytosine base pair. The calculations reveal that electron-driven interbase proton-transfer processes play an important role in the photochemistry of these systems. The exceptionally short lifetime of the UV-absorbing states of the Watson–Crick conformer is tentatively explained by the existence of a barrierless reaction path that connects the spectroscopic 1π π * excited state with the electronic ground state via two electronic curve crossings. For the non-Watson–Crick structures, the photochemically reactive state is located at higher energies, resulting in a barrier for proton transfer and, thus, a longer lifetime of the UV-absorbing 1π π * state. The computational results support the conjecture that the photochemistry of hydrogen bonds plays a decisive role for the photostability of the molecular encoding of the genetic information in isolated DNA base pairs. PMID:16330778

  15. KSC-05pd2449

    NASA Image and Video Library

    2005-11-07

    KENNEDY SPACE CENTER, FLA. - A Long-Eared Owl is spotted on Launch Complex 41 at Cape Canaveral Air Force Station in Florida. This one holds a typical stance for protecting its young. These owls range from Alaska and Canada to the Gulf states and Mexico, as far east as Central Florida. Their habitat is deciduous and evergreen forests. They nest in deserted nests of crows, hawks or squirrels.

  16. KSC-05pd2448

    NASA Image and Video Library

    2005-11-07

    KENNEDY SPACE CENTER, FLA. - A Long-Eared Owl is spotted on Launch Complex 41 at Cape Canaveral Air Force Station in Florida. This one holds a typical stance for protecting its young. These owls range from Alaska and Canada to the Gulf states and Mexico, as far east as Central Florida. Their habitat is deciduous and evergreen forests. They nest in deserted nests of crows, hawks or squirrels.

  17. KSC-00pp1083

    NASA Image and Video Library

    2000-08-06

    An international gathering of police officers march in a parade at the KSC Visitor Complex during opening ceremonies of the 2000 International Law Enforcement Games. More than 1,850 participants and their families took part in the opening, held in the Rocket Garden. The ceremony includes parades, torch lighting and a tug of war. The games feature officers from 15 countries and 37 United States in competitions around Brevard County, Fla

  18. KSC-00pp1088

    NASA Image and Video Library

    2000-08-06

    Hong Kong police officers gather in the KSC Visitor Complex Rocket Garden during opening ceremonies of the 2000 International Law Enforcement Games. More than 1,850 participants and their families took part in the opening, held in the Rocket Garden. The ceremony included parades, torch lighting and a tug of war. The games feature officers from 15 countries and 37 United States in competitions around Brevard County, Fla

  19. KSC00pp1088

    NASA Image and Video Library

    2000-08-06

    Hong Kong police officers gather in the KSC Visitor Complex Rocket Garden during opening ceremonies of the 2000 International Law Enforcement Games. More than 1,850 participants and their families took part in the opening, held in the Rocket Garden. The ceremony included parades, torch lighting and a tug of war. The games feature officers from 15 countries and 37 United States in competitions around Brevard County, Fla

  20. KSC00pp1083

    NASA Image and Video Library

    2000-08-06

    An international gathering of police officers march in a parade at the KSC Visitor Complex during opening ceremonies of the 2000 International Law Enforcement Games. More than 1,850 participants and their families took part in the opening, held in the Rocket Garden. The ceremony includes parades, torch lighting and a tug of war. The games feature officers from 15 countries and 37 United States in competitions around Brevard County, Fla

  1. KSC00pp1084

    NASA Image and Video Library

    2000-08-06

    A crowd of police officers and their families cheer a presentation of flags during opening ceremonies of the 2000 International Law Enforcement Games. Held in the KSC Visitor Complex Rocket Garden, the ceremony hosted more than 1,850 participants and their families for events that included parades, torch lighting and a tug of war. The games feature officers from 15 countries and 37 United States in competitions around Brevard County, Fla

  2. KSC-00pp1084

    NASA Image and Video Library

    2000-08-06

    A crowd of police officers and their families cheer a presentation of flags during opening ceremonies of the 2000 International Law Enforcement Games. Held in the KSC Visitor Complex Rocket Garden, the ceremony hosted more than 1,850 participants and their families for events that included parades, torch lighting and a tug of war. The games feature officers from 15 countries and 37 United States in competitions around Brevard County, Fla

  3. KSC-05PD-1601

    NASA Technical Reports Server (NTRS)

    2005-01-01

    KENNEDY SPACE CENTER, FLA. Astronaut James Reilly is interviewed in the NASA News Center at NASA Kennedy Space Center by a television reporter during launch activities for Return to Flight mission STS-114. Reilly has flown on two Shuttle missions, STS-89 and STS-104. More than a thousand media representatives from 36 states, the District of Columbia and 32 countries converged on the News Center for the historic launch.

  4. KSC-2009-3304

    NASA Image and Video Library

    2009-05-28

    CAPE CANAVERAL, Fla. – Florida Rep. Ralph Poppell (left) talks with Kennedy Space Center Director Bob Cabana during the annual Community Leaders Breakfast held in the Debus Center at Kennedy Space Center's Visitor Complex. Community leaders, business executives, educators, community organizers and state and local government heard Cabana provide an overview of operations at the space center and a look ahead at upcoming missions and activities. Photo credit: NASA/Kim Shiflett

  5. KSC-91PC-0264

    NASA Image and Video Library

    1991-02-20

    CAPE CANAVERAL, Fla. -- Vice President of the United States Dan Quayle. right. tries on a communications headset in the Launch Control Center and learns about firing room activities from Launch Director Robert Sieck. Quayle spoke with members of the STS-39 flight crew participating in the Terminal Countdown Demonstration Test, toured the launch pad and other center facilities, addressed workers and held a press conference. Image credit: NASA

  6. KSC-04pd1886

    NASA Image and Video Library

    2004-09-22

    KENNEDY SPACE CENTER, FLA. - In the Reusable Launch Vehicle (RLV) Hangar, workers stretch sheets of plastic over racks of equipment in preparation for the arrival of Hurricane Jeanne, expected to impact Central Florida Sunday. This is the fourth hurricane in 45 days to make landfall somewhere in the state. The Thermal Protection System (TPS) Facility suffered extensive damage from Hurricane Frances, causing the relocation of equipment to the RLV.

  7. 33 CFR 162.65 - All waterways tributary to the Atlantic Ocean south of Chesapeake Bay and all waterways tributary...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Atlantic Ocean south of Chesapeake Bay and all waterways tributary to the Gulf of Mexico east and south of... the Gulf of Mexico east and south of St. Marks, Fla. (a) Description. This section applies to the... or with the Gulf of Mexico east and south of St. Marks, Florida. (2) United States property. All...

  8. 33 CFR 162.65 - All waterways tributary to the Atlantic Ocean south of Chesapeake Bay and all waterways tributary...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Atlantic Ocean south of Chesapeake Bay and all waterways tributary to the Gulf of Mexico east and south of... the Gulf of Mexico east and south of St. Marks, Fla. (a) Description. This section applies to the... or with the Gulf of Mexico east and south of St. Marks, Florida. (2) United States property. All...

  9. 33 CFR 162.65 - All waterways tributary to the Atlantic Ocean south of Chesapeake Bay and all waterways tributary...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Atlantic Ocean south of Chesapeake Bay and all waterways tributary to the Gulf of Mexico east and south of... the Gulf of Mexico east and south of St. Marks, Fla. (a) Description. This section applies to the... or with the Gulf of Mexico east and south of St. Marks, Florida. (2) United States property. All...

  10. 76 FR 2134 - Notice of Lodging of Consent Decree Under the Comprehensive Environmental Response, Compensation...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-12

    ... Seven Out, LLC and BCX, Inc. (``Settling Defendants'') in United States of America v. Seven Out LLC, and BCX, Inc., Case No. 3:11-cv-0009-UAMH-MCR (U.S.D.C. M.D. Fla.), with respect to the BCX Tank Superfund... at or from the Site. Financial information provided by the Settling Defendants indicated an inability...

  11. KSC-04pd1887

    NASA Image and Video Library

    2004-09-22

    KENNEDY SPACE CENTER, FLA. - In the Reusable Launch Vehicle (RLV) Hangar, workers secure stretch sheets of plastic over racks of equipment in preparation for the arrival of Hurricane Jeanne, expected to impact Central Florida Sunday. This is the fourth hurricane in 45 days to make landfall somewhere in the state. The Thermal Protection System (TPS) Facility suffered extensive damage from Hurricane Frances, causing the relocation of equipment to the RLV.

  12. KENNEDY SPACE CENTER, FLA. - Employees check out the new chamber facilities of the Space Life Sciences Lab (SLSL), formerly known as the Space Experiment Research and Processing Laboratory (SERPL). From left are Ray Wheeler, with NASA; Debbie Wells and Larry Burns, with Dynamac; A.O. Rule, president of Environmental Growth Chambers, Inc. (ECG); Neil Yorio, with Dynamac; and John Wiezchowski, with ECG. The SLSL is a state-of-the-art facility being built for ISS biotechnology research. Developed as a partnership between NASA-KSC and the State of Florida, NASA’s life sciences contractor will be the primary tenant of the facility, leasing space to conduct flight experiment processing and NASA-sponsored research. About 20 percent of the facility will be available for use by Florida’s university researchers through the Florida Space Research Institute.

    NASA Image and Video Library

    2003-09-10

    KENNEDY SPACE CENTER, FLA. - Employees check out the new chamber facilities of the Space Life Sciences Lab (SLSL), formerly known as the Space Experiment Research and Processing Laboratory (SERPL). From left are Ray Wheeler, with NASA; Debbie Wells and Larry Burns, with Dynamac; A.O. Rule, president of Environmental Growth Chambers, Inc. (ECG); Neil Yorio, with Dynamac; and John Wiezchowski, with ECG. The SLSL is a state-of-the-art facility being built for ISS biotechnology research. Developed as a partnership between NASA-KSC and the State of Florida, NASA’s life sciences contractor will be the primary tenant of the facility, leasing space to conduct flight experiment processing and NASA-sponsored research. About 20 percent of the facility will be available for use by Florida’s university researchers through the Florida Space Research Institute.

  13. FlaF is a β-sandwich protein that anchors the archaellum in the archaeal cell envelope by binding the S-layer protein

    DOE PAGES

    Banerjee, Ankan; Tsai, Chi -Lin; Chaudhury, Paushali; ...

    2015-05-01

    Archaea employ the archaellum, a type IV pilus-like nanomachine, for swimming motility. In the crenarchaeon Sulfolobus acidocaldarius, the archaellum consists of seven proteins: FlaB/X/G/F/H/I/J. FlaF is conserved and essential for archaellum assembly but no FlaF structures exist. Here, we truncated the FlaF N terminus and solved 1.5-Å and 1.65-Å resolution crystal structures of this monotopic membrane protein. Structures revealed an N-terminal α-helix and an eight-strand β-sandwich, immunoglobulin-like fold with striking similarity to S-layer proteins. Crystal structures, X-ray scattering, and mutational analyses suggest dimer assembly is needed for in vivo function. The sole cell envelope component of S. acidocaldarius is amore » paracrystalline S-layer, and FlaF specifically bound to S-layer protein, suggesting that its interaction domain is located in the pseudoperiplasm with its N-terminal helix in the membrane. From these data, FlaF may act as the previously unknown archaellum stator protein that anchors the rotating archaellum to the archaeal cell envelope.« less

  14. Quadratic Zeeman effect for hydrogen: A method for rigorous bound-state error estimates

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Fonte, G.; Falsaperla, P.; Schiffrer, G.

    1990-06-01

    We present a variational method, based on direct minimization of energy, for the calculation of eigenvalues and eigenfunctions of a hydrogen atom in a strong uniform magnetic field in the framework of the nonrelativistic theory (quadratic Zeeman effect). Using semiparabolic coordinates and a harmonic-oscillator basis, we show that it is possible to give rigorous error estimates for both eigenvalues and eigenfunctions by applying some results of Kato (Proc. Phys. Soc. Jpn. 4, 334 (1949)). The method can be applied in this simple form only to the lowest level of given angular momentum and parity, but it is also possible tomore » apply it to any excited state by using the standard Rayleigh-Ritz diagonalization method. However, due to the particular basis, the method is expected to be more effective, the weaker the field and the smaller the excitation energy, while the results of Kato we have employed lead to good estimates only when the level spacing is not too small. We present a numerical application to the {ital m}{sup {ital p}}=0{sup +} ground state and the lowest {ital m}{sup {ital p}}=1{sup {minus}} excited state, giving results that are among the most accurate in the literature for magnetic fields up to about 10{sup 10} G.« less

  15. Motility states in bidirectional cargo transport

    NASA Astrophysics Data System (ADS)

    Klein, Sarah; Appert-Rolland, Cécile; Santen, Ludger

    2015-09-01

    Intracellular cargos which are transported by molecular motors move stochastically along cytoskeleton filaments. In particular for bidirectionally transported cargos it is an open question whether the characteristics of their motion can result from pure stochastic fluctuations or whether some coordination of the motors is needed. The results of a mean-field (MF) model of cargo-motors dynamics proposed by Müller et al. (Müller M. J. et al., Proc. Natl. Acad. Sci. U.S.A., 105 (2008) 4609) suggest the existence of states which are characterized by a symmetric bimodal distribution of cargo velocities. These states would result from a stochastic tug of war. Here we analyze the influence of the MF assumption on the cargo motion by considering a model that takes explicitly the position of each motor into account. We find that those states with symmetric bimodal distributions then disappear. As the MF model implicitly assumes some stepping synchronization between motors, we introduce a partial synchronization via an artificial mutual motor-motor activation, and show that the results of the MF model are then recovered but, even in this favorable case, only in the limit of a strong motor-motor activation and of a high number of motors. We conclude that the MF assumption is not relevant for intracellular transport.

  16. KENNEDY SPACE CENTER, FLA. - The master assembler, crane crew, removes a five-meter telescope in Cocoa Beach, Fla., for repair. The tracking telescope is part of the Distant Object Attitude Measurement System (DOAMS) that provides optical support for launches from KSC and Cape Canaveral.

    NASA Image and Video Library

    2003-08-25

    KENNEDY SPACE CENTER, FLA. - The master assembler, crane crew, removes a five-meter telescope in Cocoa Beach, Fla., for repair. The tracking telescope is part of the Distant Object Attitude Measurement System (DOAMS) that provides optical support for launches from KSC and Cape Canaveral.

  17. Innovative Methodology in the Discovery of Novel Drug Targets in the Free-Living Amoebae

    PubMed

    Baig, Abdul Mannan

    2018-04-25

    Despite advances in drug discovery and modifications in the chemotherapeutic regimens, human infections caused by free-living amoebae (FLA) have high mortality rates (~95%). The FLA that cause fatal human cerebral infections include Naegleria fowleri, Balamuthia mandrillaris and Acanthamoeba spp. Novel drug-target discovery remains the only viable option to tackle these central nervous system (CNS) infection in order to lower the mortality rates caused by the FLA. Of these FLA, N. fowleri causes primary amoebic meningoencephalitis (PAM), while the A. castellanii and B. Mandrillaris are known to cause granulomatous amoebic encephalitis (GAE). The infections caused by the FLA have been treated with drugs like Rifampin, Fluconazole, Amphotericin-B and Miltefosine. Miltefosine is an anti-leishmanial agent and an experimental anti-cancer drug. With only rare incidences of success, these drugs have remained unsuccessful to lower the mortality rates of the cerebral infection caused by FLA. Recently, with the help of bioinformatic computational tools and the discovered genomic data of the FLA, discovery of newer drug targets has become possible. These cellular targets are proteins that are either unique to the FLA or shared between the humans and these unicellular eukaryotes. The latter group of proteins has shown to be targets of some FDA approved drugs prescribed in non-infectious diseases. This review out-lines the bioinformatic methodologies that can be used in the discovery of such novel drug-targets, their chronicle by in-vitro assays done in the past and the translational value of such target discoveries in human diseases caused by FLA. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

  18. Epidemiology, Relative Invasive Ability, Molecular Characterization, and Competitive Performance of Campylobacter jejuni Strains in the Chicken Gut▿

    PubMed Central

    Pope, Christopher; Wilson, Janet; Taboada, Eduardo N.; MacKinnon, Joanne; Felipe Alves, Cristiano A.; Nash, John H. E.; Rahn, Kris; Tannock, Gerald W.

    2007-01-01

    One hundred forty-one Campylobacter jejuni isolates from humans with diarrhea and 100 isolates from retailed poultry meat were differentiated by flaA typing. The bacteria were isolated in a specific geographical area (Dunedin) in New Zealand over a common time period. Twenty nine flaA types were detected, one of which (flaA restriction fragment length polymorphism type 15 [flaA-15]) predominated among isolates from humans (∼30% of isolates). This strain was of low prevalence (5% of isolates) among poultry isolates. flaA-15 strains were five to six times more invasive of HEp2 cells in an in vitro assay than a flaA type (flaA-3) that was commonly encountered on poultry meat (23% of isolates) but was seldom associated with human illness (5%). Competitive-exclusion experiments with chickens, utilizing real-time quantitative PCR to measure the population sizes of specific strains representing flaA-15 (T1016) and flaA-3 (Pstau) in digesta, were carried out. These experiments showed that T1016 always outcompeted Pstau in the chicken intestine. Genomic comparisons of T1016 and Pstau were made using DNA microarrays representing the genome of C. jejuni NCTC 11168. These comparisons revealed differences between the strains in the gene content of the Cj1417c-to-Cj1442c region of the genome, which is associated with the formation of capsular polysaccharide. The strains differed in Penner type (T1016, O42; Pstau, O53). It was concluded that poultry meat was at least one source of human infection with C. jejuni, that some Campylobacter strains detected in poultry meat are of higher virulence for humans than others, and that bacterial attributes affecting strain virulence and commensal colonization ability may be linked. PMID:17921281

  19. I-15 San Diego, California, model validation and calibration report.

    DOT National Transportation Integrated Search

    2010-02-01

    The Integrated Corridor Management (ICM) initiative requires the calibration and validation of simulation models used in the Analysis, Modeling, and Simulation of Pioneer Site proposed integrated corridors. This report summarizes the results and proc...

  20. Boolean networks with veto functions

    NASA Astrophysics Data System (ADS)

    Ebadi, Haleh; Klemm, Konstantin

    2014-08-01

    Boolean networks are discrete dynamical systems for modeling regulation and signaling in living cells. We investigate a particular class of Boolean functions with inhibiting inputs exerting a veto (forced zero) on the output. We give analytical expressions for the sensitivity of these functions and provide evidence for their role in natural systems. In an intracellular signal transduction network [Helikar et al., Proc. Natl. Acad. Sci. USA 105, 1913 (2008), 10.1073/pnas.0705088105], the functions with veto are over-represented by a factor exceeding the over-representation of threshold functions and canalyzing functions in the same system. In Boolean networks for control of the yeast cell cycle [Li et al., Proc. Natl. Acad. Sci. USA 101, 4781 (2004), 10.1073/pnas.0305937101; Davidich et al., PLoS ONE 3, e1672 (2008), 10.1371/journal.pone.0001672], no or minimal changes to the wiring diagrams are necessary to formulate their dynamics in terms of the veto functions introduced here.

  1. Electron Gun and Collector Design for 94 GHz Gyro-amplifiers.

    NASA Astrophysics Data System (ADS)

    Nguyen, K.; Danly, B.; Levush, B.; Blank, M.; True, D.; Felch, K.; Borchard, P.

    1997-05-01

    The electrical design of the magnetron injection gun and collector for high average power TE_01 gyro-amplifiers has recently been completed using the EGUN(W.B. Herrmannsfeldt, AIP Conf. Proc. 177, pp. 45-58, 1988.) and DEMEOS(R. True, AIP Conf. Proc. 297, pp. 493-499, 1993.) codes. The gun employs an optimized double-anode geometry and a radical cathode cone angle of 500 to achieve superior beam optics that are relatively insensitive to electrode misalignments and field errors. Perpendicular velocity spread of 1.6% at an perpendicular to axial velocity ratio of 1.52 is obtained for a 6 A, 65 kV beam. The 1.28" diameter collector, which also serves as the output waveguide, has an average power density of < 350 W/cm^2 for a 59 kW average power beam. Details will be presented at the conference.

  2. High-Power Testing of 11.424-GHz Dielectric-Loaded Accelerating Structures

    NASA Astrophysics Data System (ADS)

    Gold, Steven; Gai, Wei

    2001-10-01

    Argonne National Laboratory has previously described the design, construction, and bench testing of an X-band traveling-wave accelerating structure loaded with a permittivity=20 dielectric (P. Zou et al., Rev. Sci. Instrum. 71, 2301, 2000.). We describe a new program to build a test accelerator using this structure. The accelerator will be powered by the high-power 11.424-GHz radiation from the magnicon facility at the Naval Research Laboratory ( O.A. Nezhevenko et al., Proc. PAC 2001, in press). The magnicon is expected to provide up to 30 MW from each of two WR-90 output waveguide arms in pulses of up to 1 microsecond duration, permitting tests up to a gradient of 40 MV/m. Still higher power pulses (100-500 MW) may be available at the output of an active pulse compressor driven by the magnicon ( A.L. Vikharev et al., Proc. 9th Workshop on Advanced Accelerator Concepts.).

  3. A lanthipeptide library used to identify a protein-protein interaction inhibitor.

    PubMed

    Yang, Xiao; Lennard, Katherine R; He, Chang; Walker, Mark C; Ball, Andrew T; Doigneaux, Cyrielle; Tavassoli, Ali; van der Donk, Wilfred A

    2018-04-01

    In this article we describe the production and screening of a genetically encoded library of 10 6 lanthipeptides in Escherichia coli using the substrate-tolerant lanthipeptide synthetase ProcM. This plasmid-encoded library was combined with a bacterial reverse two-hybrid system for the interaction of the HIV p6 protein with the UEV domain of the human TSG101 protein, which is a critical protein-protein interaction for HIV budding from infected cells. Using this approach, we identified an inhibitor of this interaction from the lanthipeptide library, whose activity was verified in vitro and in cell-based virus-like particle-budding assays. Given the variety of lanthipeptide backbone scaffolds that may be produced with ProcM, this method may be used for the generation of genetically encoded libraries of natural product-like lanthipeptides containing substantial structural diversity. Such libraries may be combined with any cell-based assay to identify lanthipeptides with new biological activities.

  4. Multilevel sequential Monte Carlo: Mean square error bounds under verifiable conditions

    DOE PAGES

    Del Moral, Pierre; Jasra, Ajay; Law, Kody J. H.

    2017-01-09

    We consider the multilevel sequential Monte Carlo (MLSMC) method of Beskos et al. (Stoch. Proc. Appl. [to appear]). This technique is designed to approximate expectations w.r.t. probability laws associated to a discretization. For instance, in the context of inverse problems, where one discretizes the solution of a partial differential equation. The MLSMC approach is especially useful when independent, coupled sampling is not possible. Beskos et al. show that for MLSMC the computational effort to achieve a given error, can be less than independent sampling. In this article we significantly weaken the assumptions of Beskos et al., extending the proofs tomore » non-compact state-spaces. The assumptions are based upon multiplicative drift conditions as in Kontoyiannis and Meyn (Electron. J. Probab. 10 [2005]: 61–123). The assumptions are verified for an example.« less

  5. Multilevel sequential Monte Carlo: Mean square error bounds under verifiable conditions

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Del Moral, Pierre; Jasra, Ajay; Law, Kody J. H.

    We consider the multilevel sequential Monte Carlo (MLSMC) method of Beskos et al. (Stoch. Proc. Appl. [to appear]). This technique is designed to approximate expectations w.r.t. probability laws associated to a discretization. For instance, in the context of inverse problems, where one discretizes the solution of a partial differential equation. The MLSMC approach is especially useful when independent, coupled sampling is not possible. Beskos et al. show that for MLSMC the computational effort to achieve a given error, can be less than independent sampling. In this article we significantly weaken the assumptions of Beskos et al., extending the proofs tomore » non-compact state-spaces. The assumptions are based upon multiplicative drift conditions as in Kontoyiannis and Meyn (Electron. J. Probab. 10 [2005]: 61–123). The assumptions are verified for an example.« less

  6. The Family Leukemia Association

    ERIC Educational Resources Information Center

    Pollitt, Eleanor

    1976-01-01

    An association of families of children with leukemia, the Family Leukemia Association (FLA), was recently established in Toronto. This paper discusses (a) philosophy of the FLA; (b) formative years of this organization; (c) problems encountered by leukemic children and their families; and (d) the FLA's past and future educational and social…

  7. The development of spheroidal bodies theory for proto-planetary dynamics problem solving

    NASA Astrophysics Data System (ADS)

    Krot, A. M.

    2007-08-01

    There is not a full statistical equilibrium in a gas-dust proto-planetary cloud because of long relaxation time for proto-planet formation in own gravitational field. This protoplanetary system behavior can be described by Jeans equation in partial derivations relatively a distribution function. The problem for finding a general solution of Jeans equation is connected directly with an analytical expression for potential of gravitational field. Thus, the determination of gravitational potential is the main problem of statistical dynamics for proto-planetary system. The work shows this task of protoplanetary dynamics can be solved on the basis of spheroidal bodies theory [1]-[4]. Within the framework of this theory, cosmological bodies have fuzzy outlines and are represented by means of spheroidal forms. The proposed theory follows from the conception for forming a spheroidal body as a proto-planet from dust-like nebula; it permits to derive the form of distribution functions for an immovable spheroidal body [1],[2] and rotating one [3],[4] as well as their density masses (gravitational potentials and strengths) and also to find the distribution function of specific angular momentum for the rotating spheroidal body [4]. References: [1] A.M.Krot, Achievement in Modern Radioelectronics, 1996, no.8, pp.66-81 (in Russian). [2] A.M.Krot, Proc. SPIE's 13thAnnual Intern.Symp. "AeroSense", Orlando, Florida, USA, 1999, vol.3710, pp.1248-1259. [3] A.M.Krot, Proc. 35th COSPAR Scientific Assembly, Paris, France, 2004, Abstract A-00162. [4] A.Krot, Proc. EGU General Assembly, Vienna, Austria, 2006, Geophys. Res. Abstracts, vol.8, A-00216; SRef-ID: 1607-7962/gra/.

  8. Structure of genes and an insertion element in the methane producing archaebacterium Methanobrevibacter smithii.

    PubMed

    Hamilton, P T; Reeve, J N

    1985-01-01

    DNA fragments cloned from the methanogenic archaebacterium Methanobrevibacter smithii which complement mutations in the purE and proC genes of E. coli have been sequenced. Sequence analyses, transposon mutagenesis and expression in E. coli minicells indicate that purE and proC complementations result from the synthesis of M. smithii polypeptides with molecular weights of 36,697 and 27,836 respectively. The encoding genes appear to be located in operons. The M. smithii genome contains 69% A/T basepairs (bp) which is reflected in unusual codon usages and intergenic regions containing approximately 85% A/T bp. An insertion element, designated ISM1, was found within the cloned M. smithii DNA located adjacent to the proC complementing region. ISM1 is 1381 bp in length, has 29 bp terminal inverted repeat sequences and contains one major ORF encoded in 87% of the ISM1 sequence. ISM1 is mobile, present in approximately 10 copies per genome and integration duplicates 8 bp at the site of insertion. The duplicated sequences show homology with sequences within the 29 bp terminal repeat sequence of ISM1. Comparison of our data with sequences from halophilic archaebacteria suggests that 5'GAANTTTCA and 5'TTTTAATATAAA may be consensus promoter sequences for archaebacteria. These sequences closely resemble the consensus sequences which precede Drosophila heat-shock genes (Pelham 1982; Davidson et al. 1983). Methanogens appear to employ the eubacterial system of mRNA: 16SrRNA hybridization to ensure initiation of translation; the consensus ribosome binding sequence is 5'AGGTGA.

  9. KSC-03PD-3139

    NASA Technical Reports Server (NTRS)

    2003-01-01

    KENNEDY SPACE CENTER, FLA. The Honorable Toni Jennings, lieutenant governor of the state of Florida, speaks at a dedication and ribbon-cutting ceremony for the Space Life Sciences Lab hosted by NASA-Kennedy Space Center and the state of Florida at the new lab. Completed in August, the facility encompasses more than 100,000 square feet and was formerly known as the Space Experiment Research and Processing Laboratory or SERPL. The state, through the Florida Space Authority, built the research lab which is host to NASA, NASAs Life Sciences Services contractor Dynamac Corp., Bionetics Corp., and researchers from the University of Florida. Dynamac Corp. leases the facility. The Florida Space Research Institute is responsible for gaining additional tenants from outside the NASA community.

  10. KSC-02pp1743

    NASA Image and Video Library

    2002-11-10

    KENNEDY SPACE CENTER, FLA. -- Seminole Native American Veterans serve as color guard during a pre-launch Native American ceremony at the Rocket Garden in the KSC Visitor Complex. David Nunez, U.S. Navy, carries the State of Florida Flag; David Stephen Bowers, U.S. Army, carries the Flag of the United States of America; Charles Billie Hiers, U.S. Marine Corps., carries the Seminole Tribe of Florida Flag. The ceremony was part of several days' activities commemorating John B. Herrington as the first tribally enrolled Native American astronaut to fly on a Shuttle mission. Herrington is a Mission Specialist on STS-113.

  11. KSC-04PD-0774

    NASA Technical Reports Server (NTRS)

    2004-01-01

    KENNEDY SPACE CENTER, FLA. -- Florida Gov. Jeb Bush thanks KSC Director James W. Kennedy (right) for hosting the ceremony to launch the new Florida quarter at the KSC Visitor Complex. The backdrop is a map of the United States, illustrating the state quarters issued to date. Also on stage are, from left, U.S. Mint Director Henrietta Holsman Fore, Deputy Secretary of the Treasury Samuel W. Bodman, and NASA Administrator Sean O'Keefe. The quarter celebrates Florida as the gateway to discovery -- a destination for explorers in the past, a launch site for space explorers of the future, and an inviting place for visitors today.

  12. KSC-04pd0774

    NASA Image and Video Library

    2004-04-07

    KENNEDY SPACE CENTER, FLA. -- Florida Gov. Jeb Bush thanks KSC Director James W. Kennedy (right) for hosting the ceremony to launch the new Florida quarter at the KSC Visitor Complex. The backdrop is a map of the United States, illustrating the state quarters issued to date. Also on stage are, from left, U.S. Mint Director Henrietta Holsman Fore, Deputy Secretary of the Treasury Samuel W. Bodman, and NASA Administrator Sean O'Keefe. The quarter celebrates Florida as the gateway to discovery -- a destination for explorers in the past, a launch site for space explorers of the future, and an inviting place for visitors today.

  13. Mission Assurance: Issues and Challenges

    DTIC Science & Technology

    2010-07-15

    JFQ), Summer 1995. [9] Alberts , C.J. & Dorofee, A.J., “Mission Assurance Analysis Protocol (MAAP): Assessing Risk in Complex Environments... CAMUS : Automatically Mapping Cyber Assets to Missions and Users,” Proc. of the 2010 Military Communications Conference (MILCOM 2009), 2009. [23

  14. 33 CFR 110.73 - St. Johns River, Fla.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 1 2013-07-01 2013-07-01 false St. Johns River, Fla. 110.73 Section 110.73 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.73 St. Johns River, Fla. (a) Area A. The waters lying...

  15. 33 CFR 110.74 - Marco Island, Marco River, Fla.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 1 2012-07-01 2012-07-01 false Marco Island, Marco River, Fla. 110.74 Section 110.74 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.74 Marco Island, Marco River, Fla. Beginning...

  16. 33 CFR 110.74a - Manatee River, Bradenton, Fla.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Manatee River, Bradenton, Fla. 110.74a Section 110.74a Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.74a Manatee River, Bradenton, Fla. The waters...

  17. 33 CFR 110.74 - Marco Island, Marco River, Fla.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 1 2011-07-01 2011-07-01 false Marco Island, Marco River, Fla. 110.74 Section 110.74 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.74 Marco Island, Marco River, Fla. Beginning...

  18. 33 CFR 110.74 - Marco Island, Marco River, Fla.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Marco Island, Marco River, Fla. 110.74 Section 110.74 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.74 Marco Island, Marco River, Fla. Beginning...

  19. 33 CFR 110.74a - Manatee River, Bradenton, Fla.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 1 2011-07-01 2011-07-01 false Manatee River, Bradenton, Fla. 110.74a Section 110.74a Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.74a Manatee River, Bradenton, Fla. The waters...

  20. 33 CFR 110.73 - St. Johns River, Fla.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 1 2012-07-01 2012-07-01 false St. Johns River, Fla. 110.73 Section 110.73 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.73 St. Johns River, Fla. (a) Area A. The waters lying...

  1. 33 CFR 110.74 - Marco Island, Marco River, Fla.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 1 2013-07-01 2013-07-01 false Marco Island, Marco River, Fla. 110.74 Section 110.74 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.74 Marco Island, Marco River, Fla. Beginning...

  2. 33 CFR 110.74 - Marco Island, Marco River, Fla.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 1 2014-07-01 2014-07-01 false Marco Island, Marco River, Fla. 110.74 Section 110.74 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.74 Marco Island, Marco River, Fla. Beginning...

  3. 33 CFR 110.74a - Manatee River, Bradenton, Fla.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 1 2013-07-01 2013-07-01 false Manatee River, Bradenton, Fla. 110.74a Section 110.74a Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.74a Manatee River, Bradenton, Fla. The waters...

  4. 33 CFR 110.74a - Manatee River, Bradenton, Fla.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 1 2012-07-01 2012-07-01 false Manatee River, Bradenton, Fla. 110.74a Section 110.74a Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.74a Manatee River, Bradenton, Fla. The waters...

  5. 33 CFR 110.73 - St. Johns River, Fla.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 1 2011-07-01 2011-07-01 false St. Johns River, Fla. 110.73 Section 110.73 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.73 St. Johns River, Fla. (a) Area A. The waters lying...

  6. 33 CFR 110.74a - Manatee River, Bradenton, Fla.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 1 2014-07-01 2014-07-01 false Manatee River, Bradenton, Fla. 110.74a Section 110.74a Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.74a Manatee River, Bradenton, Fla. The waters...

  7. 33 CFR 110.73 - St. Johns River, Fla.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 1 2014-07-01 2014-07-01 false St. Johns River, Fla. 110.73 Section 110.73 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.73 St. Johns River, Fla. (a) Area A. The waters lying...

  8. Importance of Flagella and Enterotoxins for Aeromonas Virulence in a Mouse Model

    EPA Science Inventory

    A genetic characterization of eight virulence factor genes, elastase, lipase, polar flagella (flaA/flaB, flaG), lateral flagella (lafA), and the enterotoxins alt, act, and ast, was performed using polymerase chain reaction with 55 drinking water and nine clinical isolates. When 1...

  9. 19 CFR 122.24 - Landing requirements for certain aircraft arriving from areas south of U.S.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ..., Fla Opa-Locka Airport. Miami, Fla Tamiami Airport. Midland, TX Midland International Airport. New Orleans, La New Orleans International Airport (Moissant Field). New Orleans, La New Orleans Lakefront.... West Palm Beach, Fla Palm Beach International Airport. Wilmington, NC New Hanover County Airport Yuma...

  10. 33 CFR 110.74b - Apollo Beach, Fla.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 1 2012-07-01 2012-07-01 false Apollo Beach, Fla. 110.74b Section 110.74b Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.74b Apollo Beach, Fla. Beginning at a point...

  11. 33 CFR 110.74b - Apollo Beach, Fla.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Apollo Beach, Fla. 110.74b Section 110.74b Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.74b Apollo Beach, Fla. Beginning at a point...

  12. 33 CFR 110.74b - Apollo Beach, Fla.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 1 2011-07-01 2011-07-01 false Apollo Beach, Fla. 110.74b Section 110.74b Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.74b Apollo Beach, Fla. Beginning at a point...

  13. 33 CFR 110.74b - Apollo Beach, Fla.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 1 2013-07-01 2013-07-01 false Apollo Beach, Fla. 110.74b Section 110.74b Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.74b Apollo Beach, Fla. Beginning at a point...

  14. 33 CFR 110.74b - Apollo Beach, Fla.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 1 2014-07-01 2014-07-01 false Apollo Beach, Fla. 110.74b Section 110.74b Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.74b Apollo Beach, Fla. Beginning at a point...

  15. Surveillance and evaluation of the infection risk of free-living amoebae and Legionella in different aquatic environments.

    PubMed

    Ji, Wen-Tsai; Hsu, Bing-Mu; Chang, Tien-Yu; Hsu, Tsui-Kang; Kao, Po-Min; Huang, Kuan-Hao; Tsai, Shiou-Feng; Huang, Yu-Li; Fan, Cheng-Wei

    2014-11-15

    Free-living amoebae (FLA) are ubiquitous in various aquatic environments. Several amoebae species are pathogenic and host other pathogens such as Legionella, but the presence of FLA and its parasites as well as the related infection risk are not well known. In this study, the presence of pathogenic FLA and Legionella in various water bodies was investigated. Water samples were collected from a river, intake areas of drinking water treatment plants, and recreational hot spring complexes in central and southern Taiwan. A total of 140 water samples were tested for the presence of Acanthamoeba spp., Naegleria spp., Vermamoeba vermiformis, and Legionella. In addition, phylogenetic characteristics and water quality parameters were also assessed. The pathogenic genotypes of FLA included Acanthamoeba T4 and Naegleria australiensis, and both were abundant in the hot spring water. In contrast, Legionella pneumophila was detected in different aquatic environments. Among the FLA assessed, V. vermiformis was most likely to coexist with Legionella spp. The total bacteria level was associated with the presence of FLA and Legionella especially in hot spring water. Taken together, FLA contamination in recreational hot springs and drinking water source warrants more attention on potential legionellosis and amoebae infections. Copyright © 2014. Published by Elsevier B.V.

  16. Free-living amoebae and their associated bacteria in Austrian cooling towers: a 1-year routine screening.

    PubMed

    Scheikl, Ute; Tsao, Han-Fei; Horn, Matthias; Indra, Alexander; Walochnik, Julia

    2016-09-01

    Free-living amoebae (FLA) are widely spread in the environment and known to cause rare but often serious infections. Besides this, FLA may serve as vehicles for bacterial pathogens. In particular, Legionella pneumophila is known to replicate within FLA thereby also gaining enhanced infectivity. Cooling towers have been the source of outbreaks of Legionnaires' disease in the past and are thus usually screened for legionellae on a routine basis, not considering, however, FLA and their vehicle function. The aim of this study was to incorporate a screening system for host amoebae into a Legionella routine screening. A new real-time PCR-based screening system for various groups of FLA was established. Three cooling towers were screened every 2 weeks over the period of 1 year for FLA and Legionella spp., by culture and molecular methods in parallel. Altogether, 83.3 % of the cooling tower samples were positive for FLA, Acanthamoeba being the dominating genus. Interestingly, 69.7 % of the cooling tower samples were not suitable for the standard Legionella screening due to their high organic burden. In the remaining samples, positivity for Legionella spp. was 25 % by culture, but overall positivity was 50 % by molecular methods. Several amoebal isolates revealed intracellular bacteria.

  17. Vehicle-dependent disposition kinetics of fluoranthene in Fisher-344 rats.

    PubMed

    Harris, Deacqunita L; Hood, Darry B; Ramesh, Aramandla

    2008-03-01

    The objective of this study was to evaluate how the vehicles of choice affect the pharmacokinetics of orally administered Fluoranthene [FLA] in rats. Fluoranthene is a member of the family of Polycyclic Aromatic Hydrocarbon chemicals. Fluoranthene exposure to humans may occur as a result of cigarette smoking, consumption of contaminated food and water, heating woods in stoves and boilers, industrial sources such as coal gasification, carbon and graphite electrode manufacturing. Adult male Fisher-344 rats were given single oral doses of 25 and 50 microg/kg FLA in tricaprylin, peanut oil, cod liver oil, Tween 80/isotonic saline (1:5) and 2% Alkamuls-EL620 through gavage. After administration, the rats were housed individually in metabolic cages and sacrificed at 2, 4, 6, 8, 10 and 12 hours post FLA exposure. Blood, lung, liver, small intestine, adipose tissue samples, urine, and feces were collected at each time point. Samples were subjected to a liquid-liquid extraction using methanol, chloroform, and water. The extracts were analyzed by a reverse-phase HPLC, equipped with a fluorescence detector. The results revealed a dose-dependent increase in FLA concentrations in plasma and tissues for all the vehicles used. Plasma and tissue FLA concentrations were greater for peanut oil; cod liver oil, and tricaprylin vehicles compared to Alkamuls (p < 0.05), and Tween 80/isotonic saline (1:5). Most of the FLA administered through peanut oil, cod liver oil and tricaprylin was cleared from the body by 8 hours (90%) and 12 hours (80%) post administration for the 25 microg/kg and 50 microg/kg dose groups, respectively. With both doses employed, the metabolism of FLA was highest when cod liver oil was used as a vehicle and lowest in vehicles containing detergent/water [cod liver oil > peanut oil > tricaprylin > alkamuls > Tween 80/isotonic saline (1:5)]. These findings suggest that uptake and elimination of FLA is accelerated when administered through oil-based vehicles. The low uptake of FLA from Alkamuls and Tween 80/isotonic saline may have been a result of the poor solubility of the chemical. In summary, our findings reiterate that absorption characteristics of FLA were governed by the dose as well as the dosing vehicle. The vehicle-dependent bioavailability of FLA suggests a need for the judicious selection of vehicles in evaluating oral toxicity studies for risk assessment purposes.

  18. KSC-04pd0879

    NASA Image and Video Library

    2004-04-16

    KENNEDY SPACE CENTER, FLA. - Two fledgling ospreys occupy a nest near the NASA-KSC News Center, across from the Vehicle Assembly Building. Known as a fish hawk, ospreys select sites of opportunity, from trees and telephone poles to rocks or even flat ground. In the United States they are found from Alaska to Florida and the Gulf Coast. Osprey nests are found throughout the Kennedy Space Center and nearby Merritt Island National Wildlife Refuge.

  19. KSC00pp1085

    NASA Image and Video Library

    2000-08-06

    British police officers carry their country’s flag while marching in a parade at the KSC Visitor Complex during opening ceremonies of the 2000 International Law Enforcement Games. More than 1,850 participants and their families took part in the opening, held in the Rocket Garden. The ceremony included parades, torch lighting and a tug of war. The games feature officers from 15 countries and 37 United States in competitions around Brevard County, Fla

  20. KSC-00pp1082

    NASA Image and Video Library

    2000-08-06

    U.S. Police officers join the KSC Space Man in a parade at the KSC Visitor Complex during opening ceremonies of the 2000 International Law Enforcement Games. More than 1,850 participants and their families took part in the opening, held in the Rocket Garden. The ceremony includes parades, torch lighting and a tug of war. The games feature officers from 15 countries and 37 United States in competitions around Brevard County, Fla

  1. Opening ceremonies of the 2000 Law Enforcement Games held at KSC

    NASA Technical Reports Server (NTRS)

    2000-01-01

    Canadian police officers gather in the KSC Visitor Complex Rocket Garden during opening ceremonies of the 2000 International Law Enforcement Games. More than 1,850 participants and their families took part in the opening, held in the Rocket Garden. The ceremony included parades, torch lighting and a tug of war. The games feature officers from 15 countries and 37 United States in competitions around Brevard County, Fla.

  2. KSC00pp1082

    NASA Image and Video Library

    2000-08-06

    U.S. Police officers join the KSC Space Man in a parade at the KSC Visitor Complex during opening ceremonies of the 2000 International Law Enforcement Games. More than 1,850 participants and their families took part in the opening, held in the Rocket Garden. The ceremony includes parades, torch lighting and a tug of war. The games feature officers from 15 countries and 37 United States in competitions around Brevard County, Fla

  3. Opening ceremonies of the 2000 Law Enforcement Games held at KSC

    NASA Technical Reports Server (NTRS)

    2000-01-01

    A crowd of police officers and their families attend opening ceremonies of the 2000 International Law Enforcement Games. Held in the KSC Visitor Complex Rocket Garden, the ceremony hosted more than 1,850 participants and their families for events that included parades, torch lighting and a tug of war. The games feature officers from 15 countries and 37 United States in competitions around Brevard County, Fla.

  4. Opening ceremonies of the 2000 Law Enforcement Games held at KSC

    NASA Technical Reports Server (NTRS)

    2000-01-01

    Hong Kong police officers gather in the KSC Visitor Complex Rocket Garden during opening ceremonies of the 2000 International Law Enforcement Games. More than 1,850 participants and their families took part in the opening, held in the Rocket Garden. The ceremony included parades, torch lighting and a tug of war. The games feature officers from 15 countries and 37 United States in competitions around Brevard County, Fla.

  5. KSC-00pp1085

    NASA Image and Video Library

    2000-08-06

    British police officers carry their country’s flag while marching in a parade at the KSC Visitor Complex during opening ceremonies of the 2000 International Law Enforcement Games. More than 1,850 participants and their families took part in the opening, held in the Rocket Garden. The ceremony included parades, torch lighting and a tug of war. The games feature officers from 15 countries and 37 United States in competitions around Brevard County, Fla

  6. 2015-1252

    NASA Image and Video Library

    2015-01-29

    CAPE CANAVERAL, Fla. – First Lady of the State of Florida Ann Scott speaks to students, parents and guests inside the Astronaut Encounter Theater at NASA’s Kennedy Space Center in Florida during the 2015 Celebrate Literacy Week Florida PSA Awards program. The event, hosted by the Florida Department of Education, announced the winning entries from elementary, middle and high school students that best encouraged literacy and its connection to space careers. Photo credit: NASA/Ben Smegelsky

  7. KSC-2015-1250

    NASA Image and Video Library

    2015-01-29

    CAPE CANAVERAL, Fla. – First Lady of the State of Florida Ann Scott greets students inside the Astronaut Encounter Theater at NASA’s Kennedy Space Center in Florida during the 2015 Celebrate Literacy Week Florida PSA Awards program. The event, hosted by the Florida Department of Education, announced the winning entries from elementary, middle and high school students that best encouraged literacy and its connection to space careers. Photo credit: NASA/Ben Smegelsky

  8. KSC-2015-1251

    NASA Image and Video Library

    2015-01-29

    CAPE CANAVERAL, Fla. – First Lady of the State of Florida Ann Scott greets students inside the Astronaut Encounter Theater at NASA’s Kennedy Space Center in Florida during the 2015 Celebrate Literacy Week Florida PSA Awards program. The event, hosted by the Florida Department of Education, announced the winning entries from elementary, middle and high school students that best encouraged literacy and its connection to space careers. Photo credit: NASA/Ben Smegelsky

  9. KSC-03pd1452

    NASA Image and Video Library

    2003-05-06

    KENNEDY SPACE CENTER, FLA. - Valerie Cassanto and Bob McLean talk to a reporter about experiments found during the search for Columbia debris. Cassanto is with Instrumentation Technology Associates Inc. and McLean is with the Southwest Texas State University. Included in the Commercial ITA Biomedical Experiments payload on mission STS-107 are urokinase cancer research, microencapsulation of drugs, the Growth of Bacterial Biofilm on Surfaces during Spaceflight (GOBBSS), and tin crystal formation.

  10. KSC-02pd0432

    NASA Image and Video Library

    2002-03-29

    KENNEDY SPACE CENTER, FLA. - A Short-Billed Dowitcher perches on a branch hanging above water near Kennedy Space Center,. These sandpiper-like birds inhabit mud flats, creeks, salt marshes and tidal estuaries. With their long bills probing the water in rapid up-and-down motion, they seek marine worms, snails, tiny crustaceans and aquatic larvae. They range from southern Alaska to eastern Canada and winter from the southern United States to central South America.

  11. KSC-2013-3002

    NASA Image and Video Library

    2013-06-29

    CAPE CANAVERAL, Fla. -- At the Kennedy Space Center Visitor Complex in Florida, the "rocket garden" includes many of the historic launch vehicles of the United States' efforts to explore space. The new $100 million facility includes interactive exhibits that tell the story of the 30-year Space Shuttle Program and highlight the future of space exploration. The "Space Shuttle Atlantis" exhibit formally opened to the public on June 29, 2013.Photo credit: NASA/Jim Grossmann

  12. KSC-03PD-1470

    NASA Technical Reports Server (NTRS)

    2003-01-01

    KENNEDY SPACE CENTER, FLA. - From left, Bob McLean, Southwest Texas State University, and Valerie Cassanto, Instrumentation Technology Associates, Inc., study one of the experiments carried on mission STS-107. Several experiments were found during the search for Columbia debris. Included in the Commercial ITA Biomedical Experiments payload on mission STS-107 are urokinase cancer research, microencapsulation of drugs, the Growth of Bacterial Biofilm on Surfaces during Spaceflight (GOBBSS), and tin crystal formation.

  13. KSC-03PD-1452

    NASA Technical Reports Server (NTRS)

    2003-01-01

    KENNEDY SPACE CENTER, FLA. - Valerie Cassanto and Bob McLean talk to a reporter about experiments found during the search for Columbia debris. Cassanto is with Instrumentation Technology Associates Inc. and McLean is with the Southwest Texas State University. Included in the Commercial ITA Biomedical Experiments payload on mission STS-107 are urokinase cancer research, microencapsulation of drugs, the Growth of Bacterial Biofilm on Surfaces during Spaceflight (GOBBSS), and tin crystal formation.

  14. Finite-element modeling of soft tissue rolling indentation.

    PubMed

    Sangpradit, Kiattisak; Liu, Hongbin; Dasgupta, Prokar; Althoefer, Kaspar; Seneviratne, Lakmal D

    2011-12-01

    We describe a finite-element (FE) model for simulating wheel-rolling tissue deformations using a rolling FE model (RFEM). A wheeled probe performing rolling tissue indentation has proven to be a promising approach for compensating for the loss of haptic and tactile feedback experienced during robotic-assisted minimally invasive surgery (H. Liu, D. P. Noonan, B. J. Challacombe, P. Dasgupta, L. D. Seneviratne, and K. Althoefer, "Rolling mechanical imaging for tissue abnormality localization during minimally invasive surgery, " IEEE Trans. Biomed. Eng., vol. 57, no. 2, pp. 404-414, Feb. 2010; K. Sangpradit, H. Liu, L. Seneviratne, and K. Althoefer, "Tissue identification using inverse finite element analysis of rolling indentation," in Proc. IEEE Int. Conf. Robot. Autom. , Kobe, Japan, 2009, pp. 1250-1255; H. Liu, D. Noonan, K. Althoefer, and L. Seneviratne, "The rolling approach for soft tissue modeling and mechanical imaging during robot-assisted minimally invasive surgery," in Proc. IEEE Int. Conf. Robot. Autom., May 2008, pp. 845-850; H. Liu, P. Puangmali, D. Zbyszewski, O. Elhage, P. Dasgupta, J. S. Dai, L. Seneviratne, and K. Althoefer, "An indentation depth-force sensing wheeled probe for abnormality identification during minimally invasive surgery," Proc. Inst. Mech. Eng., H, vol. 224, no. 6, pp. 751-63, 2010; D. Noonan, H. Liu, Y. Zweiri, K. Althoefer, and L. Seneviratne, "A dual-function wheeled probe for tissue viscoelastic property identification during minimally invasive surgery," in Proc. IEEE Int. Conf. Robot. Autom. , 2008, pp. 2629-2634; H. Liu, J. Li, Q. I. Poon, L. D. Seneviratne, and K. Althoefer, "Miniaturized force indentation-depth sensor for tissue abnormality identification," IEEE Int. Conf. Robot. Autom., May 2010, pp. 3654-3659). A sound understanding of wheel-tissue rolling interaction dynamics will facilitate the evaluation of signals from rolling indentation. In this paper, we model the dynamic interactions between a wheeled probe and a soft tissue sample using the ABAQUS FE software package. The aim of this work is to more precisely locate abnormalities within soft tissue organs using RFEM and hence aid surgeons to improve diagnostic ability. The soft tissue is modeled as a nonlinear hyperelastic material with geometrical nonlinearity. The proposed RFEM was validated on a silicone phantom and a porcine kidney sample. The results show that the proposed method can predict the wheel-tissue interaction forces of rolling indentation with good accuracy and can also accurately identify the location and depth of simulated tumors.

  15. KENNEDY SPACE CENTER, FLA. -- KSC management and other employees gather in the Center’s television studio to watch the address by President George W. Bush at NASA Headquarters in Washington, D.C., stating his goals for NASA’s new mission: Completing the International Space Station, retiring the Space Shuttle orbiters, developing a new crew exploration vehicle, and returning to the moon and beyond within the next two decades. Pres. Bush was welcomed by NASA Administrator Sean O’Keefe and Expedition 8 Commander Michael Foale, who greeted him from the International Space Station. Members of the Washington, D.C., audience included astronauts Eileen Collins, Ed Lu and Michael Lopez-Alegria, and former astronaut Gene Cernan.

    NASA Image and Video Library

    2004-01-14

    KENNEDY SPACE CENTER, FLA. -- KSC management and other employees gather in the Center’s television studio to watch the address by President George W. Bush at NASA Headquarters in Washington, D.C., stating his goals for NASA’s new mission: Completing the International Space Station, retiring the Space Shuttle orbiters, developing a new crew exploration vehicle, and returning to the moon and beyond within the next two decades. Pres. Bush was welcomed by NASA Administrator Sean O’Keefe and Expedition 8 Commander Michael Foale, who greeted him from the International Space Station. Members of the Washington, D.C., audience included astronauts Eileen Collins, Ed Lu and Michael Lopez-Alegria, and former astronaut Gene Cernan.

  16. KENNEDY SPACE CENTER, FLA. - In the RLV Hangar, Adm. Harold Gehman, chairman of the Columbia Investigation Accident Board, points to data on a chart. He and other board members are visiting as part of the ongoing investigation. Recovery efforts as of May 5 included 82,500 pieces of debris weighing 84,800 pounds, almost 40 percent of the total dry weight of the shuttle. About 25,000 personnel took part, utilizing almost 1.5 million total man-hours in the recovery effort and involving more than 130 federal, state and local agencies. The operation was also supported by more than 270 organizations that included businesses and volunteer groups.

    NASA Image and Video Library

    2003-05-15

    KENNEDY SPACE CENTER, FLA. - In the RLV Hangar, Adm. Harold Gehman, chairman of the Columbia Investigation Accident Board, points to data on a chart. He and other board members are visiting as part of the ongoing investigation. Recovery efforts as of May 5 included 82,500 pieces of debris weighing 84,800 pounds, almost 40 percent of the total dry weight of the shuttle. About 25,000 personnel took part, utilizing almost 1.5 million total man-hours in the recovery effort and involving more than 130 federal, state and local agencies. The operation was also supported by more than 270 organizations that included businesses and volunteer groups.

  17. KENNEDY SPACE CENTER, FLA. - Reporters at the dedication ceremony of a NASA hangar at the San Jose, Costa Rica, airport observe the WB-57f takeoff for its sixth Costa Rican flight. KSC and NASA researchers are testing the Aircraft-based Volcanic Emission Mass Spectrometer (AVEMS) that determines the presence and concentration of various chemicals. It is being tested in flights over the Turrialba volcano in Costa Rica, and in the crater, sampling and analyzing fresh volcanic gases in their natural chemical state. The AVEMS system has been developed for use in the Space Shuttle program, to detect toxic gas leaks and emissions in the Shuttle’s aft compartment and the crew compartment.

    NASA Image and Video Library

    2003-03-31

    KENNEDY SPACE CENTER, FLA. - Reporters at the dedication ceremony of a NASA hangar at the San Jose, Costa Rica, airport observe the WB-57f takeoff for its sixth Costa Rican flight. KSC and NASA researchers are testing the Aircraft-based Volcanic Emission Mass Spectrometer (AVEMS) that determines the presence and concentration of various chemicals. It is being tested in flights over the Turrialba volcano in Costa Rica, and in the crater, sampling and analyzing fresh volcanic gases in their natural chemical state. The AVEMS system has been developed for use in the Space Shuttle program, to detect toxic gas leaks and emissions in the Shuttle’s aft compartment and the crew compartment.

  18. Cartographic production for the Florida Shelf Habitat (FLaSH) map study: generation of surface grids, contours, and KMZ files

    USGS Publications Warehouse

    Robbins, Lisa L.; Hansen, Mark; Raabe, Ellen; Knorr, Paul O.; Browne, Joseph

    2007-01-01

    The Florida shelf represents a finite source of economic resources, including commercial and recreational fisheries, tourism, recreation, sand and gravel resources, phosphate, and freshwater reserves. Yet the basic information needed to locate resources, or to interpret and utilize existing data, comes from many sources, dates, and formats. A multi-agency effort is underway to coordinate and prioritize the compilation of suitable datasets for an integrated information system of Florida’s coastal and ocean resources. This report and the associated data files represent part of the effort to make data accessible and useable with computer-mapping systems, web-based technologies, and user-friendly visualization tools. Among the datasets compiled and developed are seafloor imagery, marine sediment data, and existing bathymetric data. A U.S. Geological Survey-sponsored workshop in January 2007 resulted in the establishment of mapping priorities for the state. Bathymetry was identified as a common priority among agencies and researchers. State-of-the-art computer-mapping techniques and data-processing tools were used to develop shelf-wide raster and vector data layers. Florida Shelf Habitat (FLaSH) Mapping Project (http://coastal.er.usgs.gov/flash) endeavors to locate available data, identify data gaps, synthesize existing information, and expand our understanding of geologic processes in our dynamic coastal and marine systems.

  19. KENNEDY SPACE CENTER, FLA. - At the Astrotech Space Operations processing facilities, NASA’s MESSENGER spacecraft is secure after transfer to the work stand. There employees of the Johns Hopkins University Applied Physics Laboratory, builders of the spacecraft, will perform an initial state-of-health check. Then processing for launch can begin, including checkout of the power systems, communications systems and control systems. The thermal blankets will also be attached for flight. MESSENGER - short for MErcury Surface, Space ENvironment, GEochemistry and Ranging - will be launched May 11 on a six-year mission aboard a Boeing Delta II rocket. Liftoff is targeted for 2:26 a.m. EDT on Tuesday, May 11.

    NASA Image and Video Library

    2004-03-10

    KENNEDY SPACE CENTER, FLA. - At the Astrotech Space Operations processing facilities, NASA’s MESSENGER spacecraft is secure after transfer to the work stand. There employees of the Johns Hopkins University Applied Physics Laboratory, builders of the spacecraft, will perform an initial state-of-health check. Then processing for launch can begin, including checkout of the power systems, communications systems and control systems. The thermal blankets will also be attached for flight. MESSENGER - short for MErcury Surface, Space ENvironment, GEochemistry and Ranging - will be launched May 11 on a six-year mission aboard a Boeing Delta II rocket. Liftoff is targeted for 2:26 a.m. EDT on Tuesday, May 11.

  20. KENNEDY SPACE CENTER, FLA. - At the Astrotech Space Operations processing facilities, NASA’s MESSENGER spacecraft is lifted off the pallet for transfer to a work stand. There employees of the Johns Hopkins University Applied Physics Laboratory, builders of the spacecraft, will perform an initial state-of-health check. Then processing for launch can begin, including checkout of the power systems, communications systems and control systems. The thermal blankets will also be attached for flight. MESSENGER - short for MErcury Surface, Space ENvironment, GEochemistry and Ranging - will be launched May 11 on a six-year mission aboard a Boeing Delta II rocket. Liftoff is targeted for 2:26 a.m. EDT on Tuesday, May 11.

    NASA Image and Video Library

    2004-03-10

    KENNEDY SPACE CENTER, FLA. - At the Astrotech Space Operations processing facilities, NASA’s MESSENGER spacecraft is lifted off the pallet for transfer to a work stand. There employees of the Johns Hopkins University Applied Physics Laboratory, builders of the spacecraft, will perform an initial state-of-health check. Then processing for launch can begin, including checkout of the power systems, communications systems and control systems. The thermal blankets will also be attached for flight. MESSENGER - short for MErcury Surface, Space ENvironment, GEochemistry and Ranging - will be launched May 11 on a six-year mission aboard a Boeing Delta II rocket. Liftoff is targeted for 2:26 a.m. EDT on Tuesday, May 11.

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