Sample records for process requiring continuous

  1. 40 CFR 63.11975 - What are my continuous compliance requirements for process wastewater?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... requirements for process wastewater? 63.11975 Section 63.11975 Protection of Environment ENVIRONMENTAL... What are my continuous compliance requirements for process wastewater? (a) For each process wastewater... in paragraph (b) of this section. For each process wastewater stream for which you initially...

  2. 40 CFR 63.11975 - What are my continuous compliance requirements for process wastewater?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... requirements for process wastewater? 63.11975 Section 63.11975 Protection of Environment ENVIRONMENTAL... What are my continuous compliance requirements for process wastewater? (a) For each process wastewater... in paragraph (b) of this section. For each process wastewater stream for which you initially...

  3. 40 CFR 63.11975 - What are my continuous compliance requirements for process wastewater?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... requirements for process wastewater? 63.11975 Section 63.11975 Protection of Environment ENVIRONMENTAL... What are my continuous compliance requirements for process wastewater? (a) For each process wastewater... in paragraph (b) of this section. For each process wastewater stream for which you initially...

  4. 40 CFR 63.2455 - What requirements must I meet for continuous process vents?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... CATEGORIES National Emission Standards for Hazardous Air Pollutants: Miscellaneous Organic Chemical... any continuous process vent that is combined with Group 1 batch process vents before a control device or recovery device because the requirements of § 63.2450(c)(2)(i) apply to the combined stream. (2...

  5. Transfer of a three step mAb chromatography process from batch to continuous: Optimizing productivity to minimize consumable requirements.

    PubMed

    Gjoka, Xhorxhi; Gantier, Rene; Schofield, Mark

    2017-01-20

    The goal of this study was to adapt a batch mAb purification chromatography platform for continuous operation. The experiments and rationale used to convert from batch to continuous operation are described. Experimental data was used to design chromatography methods for continuous operation that would exceed the threshold for critical quality attributes and minimize the consumables required as compared to batch mode of operation. Four unit operations comprising of Protein A capture, viral inactivation, flow-through anion exchange (AEX), and mixed-mode cation exchange chromatography (MMCEX) were integrated across two Cadence BioSMB PD multi-column chromatography systems in order to process a 25L volume of harvested cell culture fluid (HCCF) in less than 12h. Transfer from batch to continuous resulted in an increase in productivity of the Protein A step from 13 to 50g/L/h and of the MMCEX step from 10 to 60g/L/h with no impact on the purification process performance in term of contaminant removal (4.5 log reduction of host cell proteins, 50% reduction in soluble product aggregates) and overall chromatography process yield of recovery (75%). The increase in productivity, combined with continuous operation, reduced the resin volume required for Protein A and MMCEX chromatography by more than 95% compared to batch. The volume of AEX membrane required for flow through operation was reduced by 74%. Moreover, the continuous process required 44% less buffer than an equivalent batch process. This significant reduction in consumables enables cost-effective, disposable, single-use manufacturing. Copyright © 2016 The Authors. Published by Elsevier B.V. All rights reserved.

  6. 40 CFR 74.17 - Application requirements for process sources. [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 16 2010-07-01 2010-07-01 false Application requirements for process sources. [Reserved] 74.17 Section 74.17 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) SULFUR DIOXIDE OPT-INS Permitting Procedures § 74.17 Application...

  7. 40 CFR 63.9632 - What are the installation, operation, and maintenance requirements for my monitoring equipment?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS FOR SOURCE CATEGORIES (CONTINUED) National Emission Standards for Hazardous Air Pollutants: Taconite Iron Ore Processing Continuous Compliance Requirements § 63.9632 What are...

  8. 40 CFR 63.9632 - What are the installation, operation, and maintenance requirements for my monitoring equipment?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS FOR SOURCE CATEGORIES (CONTINUED) National Emission Standards for Hazardous Air Pollutants: Taconite Iron Ore Processing Continuous Compliance Requirements § 63.9632 What are...

  9. Superior memory efficiency of quantum devices for the simulation of continuous-time stochastic processes

    NASA Astrophysics Data System (ADS)

    Elliott, Thomas J.; Gu, Mile

    2018-03-01

    Continuous-time stochastic processes pervade everyday experience, and the simulation of models of these processes is of great utility. Classical models of systems operating in continuous-time must typically track an unbounded amount of information about past behaviour, even for relatively simple models, enforcing limits on precision due to the finite memory of the machine. However, quantum machines can require less information about the past than even their optimal classical counterparts to simulate the future of discrete-time processes, and we demonstrate that this advantage extends to the continuous-time regime. Moreover, we show that this reduction in the memory requirement can be unboundedly large, allowing for arbitrary precision even with a finite quantum memory. We provide a systematic method for finding superior quantum constructions, and a protocol for analogue simulation of continuous-time renewal processes with a quantum machine.

  10. 40 CFR 63.9631 - What are my monitoring requirements?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 14 2011-07-01 2011-07-01 false What are my monitoring requirements? 63.9631 Section 63.9631 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... (CONTINUED) National Emission Standards for Hazardous Air Pollutants: Taconite Iron Ore Processing Continuous...

  11. 40 CFR 63.2480 - What requirements must I meet for equipment leaks?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... affected source. (5) For pumps in light liquid service in an MCPU that has no continuous process vents and.../vapor and light liquid service at an existing source, you may elect to comply with the requirements in... light liquid service in an MCPU that has no continuous process vents and is part of an existing source...

  12. Facility design consideration for continuous mix production of class 1.3 propellant

    NASA Technical Reports Server (NTRS)

    Williamson, K. L.; Schirk, P. G.

    1994-01-01

    In November of 1989, NASA awarded the Advanced Solid Rocket Motor (ASRM) contract to Lockheed Missiles and Space Company (LMSC) for production of advanced solid rocket motors using the continuous mix process. Aerojet ASRM division (AAD) was selected as the facility operator and RUST International Corporation provided the engineering, procurement, and construction management services. The continuous mix process mandates that the mix and cast facilities be 'close-coupled' along with the premix facilities, creating unique and challenging requirements for the facility designer. The classical approach to handling energetic materials-division into manageable quantities, segregation, and isolation-was not available due to these process requirements and quantities involved. This paper provides a description of the physical facilities, the continuous mix process, and discusses the monitoring and detection techniques used to mitigate hazards and prevent an incident.

  13. Achieving continuous manufacturing: technologies and approaches for synthesis, workup, and isolation of drug substance. May 20-21, 2014 Continuous Manufacturing Symposium.

    PubMed

    Baxendale, Ian R; Braatz, Richard D; Hodnett, Benjamin K; Jensen, Klavs F; Johnson, Martin D; Sharratt, Paul; Sherlock, Jon-Paul; Florence, Alastair J

    2015-03-01

    This whitepaper highlights current challenges and opportunities associated with continuous synthesis, workup, and crystallization of active pharmaceutical ingredients (drug substances). We describe the technologies and requirements at each stage and emphasize the different considerations for developing continuous processes compared with batch. In addition to the specific sequence of operations required to deliver the necessary chemical and physical transformations for continuous drug substance manufacture, consideration is also given to how adoption of continuous technologies may impact different manufacturing stages in development from discovery, process development, through scale-up and into full scale production. The impact of continuous manufacture on drug substance quality and the associated challenges for control and for process safety are also emphasized. In addition to the technology and operational considerations necessary for the adoption of continuous manufacturing (CM), this whitepaper also addresses the cultural, as well as skills and training, challenges that will need to be met by support from organizations in order to accommodate the new work flows. Specific action items for industry leaders are: Develop flow chemistry toolboxes, exploiting the advantages of flow processing and including highly selective chemistries that allow use of simple and effective continuous workup technologies. Availability of modular or plug and play type equipment especially for workup to assist in straightforward deployment in the laboratory. As with learning from other industries, standardization is highly desirable and will require cooperation across industry and academia to develop and implement. Implement and exploit process analytical technologies (PAT) for real-time dynamic control of continuous processes. Develop modeling and simulation techniques to support continuous process development and control. Progress is required in multiphase systems such as crystallization. Involve all parts of the organization from discovery, research and development, and manufacturing in the implementation of CM. Engage with academia to develop the training provision to support the skills base for CM, particularly in flow chemistry, physical chemistry, and chemical engineering skills at the chemistry-process interface. Promote and encourage publication and dissemination of examples of CM across the sector to demonstrate capability, engage with regulatory comment, and establish benchmarks for performance and highlight challenges. Develop the economic case for CM of drug substance. This will involve various stakeholders at project and business level, however establishing the critical economic drivers is critical to driving the transformation in manufacturing. © 2014 Wiley Periodicals, Inc. and the American Pharmacists Association.

  14. Orodispersible films: Product transfer from lab-scale to continuous manufacturing.

    PubMed

    Thabet, Yasmin; Breitkreutz, Joerg

    2018-01-15

    Orodispersible films have been described as new beneficial dosage forms for special patient populations. Due to various production settings, different requirements on film formulations are required for non- continuous and continuous manufacturing. In this study, a continuous coating machine was qualified in regards of the process conditions for film compositions and their effects on the formed films. To investigate differences between both manufacturing processes, various film formulations of hydrochlorothiazide and hydroxypropylcellulose (HPC) or hydroxypropylmethycellulose (HPMC) as film formers were produced and the resulting films were characterized. The qualification of the continuously operating coating machine reveals no uniform heat distribution during drying. Coating solutions for continuous manufacturing should provide at least a dynamic viscosity of 1 Pa*s (wet film thickness of 500 μm, velocity of 15.9 cm/min). HPC films contain higher residuals of ethanol or acetone in bench-scale than in continuous production mode. Continuous production lead to lower drug content of the films. All continuously produced films disintegrate within less than 30 s. There are observed significant effects of the production process on the film characteristics. When transferring film manufacturing from lab-scale to continuous mode, film compositions, processing conditions and suitable characterization methods have to be carefully selected and adopted. Copyright © 2017 Elsevier B.V. All rights reserved.

  15. 40 CFR 145.58 - Procedure for processing an Indian Tribe's application.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Tribe's application. 145.58 Section 145.58 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS (CONTINUED) STATE UIC PROGRAM REQUIREMENTS Indian Tribes § 145.58 Procedure for processing an Indian Tribe's application. (a) The Administrator shall process a completed application of an...

  16. 40 CFR 145.58 - Procedure for processing an Indian Tribe's application.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Tribe's application. 145.58 Section 145.58 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS (CONTINUED) STATE UIC PROGRAM REQUIREMENTS Indian Tribes § 145.58 Procedure for processing an Indian Tribe's application. (a) The Administrator shall process a completed application of an...

  17. 40 CFR 145.58 - Procedure for processing an Indian Tribe's application.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Tribe's application. 145.58 Section 145.58 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS (CONTINUED) STATE UIC PROGRAM REQUIREMENTS Indian Tribes § 145.58 Procedure for processing an Indian Tribe's application. (a) The Administrator shall process a completed application of an...

  18. 42 CFR 3.102 - Process and requirements for initial and continued listing of PSOs.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... SERVICES GENERAL PROVISIONS PATIENT SAFETY ORGANIZATIONS AND PATIENT SAFETY WORK PRODUCT PSO Requirements... continued listing as a PSO by submitting a completed certification form that meets the requirements of this... delisted; (vi) Attest that the PSO will promptly notify the Secretary during its period of listing if it...

  19. 40 CFR 63.11562 - What are my initial compliance requirements?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... CATEGORIES (CONTINUED) National Emission Standards for Hazardous Air Pollutants for Area Sources: Asphalt Processing and Asphalt Roofing Manufacturing Standards and Compliance Requirements § 63.11562 What are my initial compliance requirements? (a) For asphalt processing operations, you must: (1) Demonstrate initial...

  20. 40 CFR 63.11562 - What are my initial compliance requirements?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... CATEGORIES (CONTINUED) National Emission Standards for Hazardous Air Pollutants for Area Sources: Asphalt Processing and Asphalt Roofing Manufacturing Standards and Compliance Requirements § 63.11562 What are my initial compliance requirements? (a) For asphalt processing operations, you must: (1) Demonstrate initial...

  1. 40 CFR 63.11562 - What are my initial compliance requirements?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... CATEGORIES (CONTINUED) National Emission Standards for Hazardous Air Pollutants for Area Sources: Asphalt Processing and Asphalt Roofing Manufacturing Standards and Compliance Requirements § 63.11562 What are my initial compliance requirements? (a) For asphalt processing operations, you must: (1) Demonstrate initial...

  2. 40 CFR 63.11562 - What are my initial compliance requirements?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... CATEGORIES (CONTINUED) National Emission Standards for Hazardous Air Pollutants for Area Sources: Asphalt Processing and Asphalt Roofing Manufacturing Standards and Compliance Requirements § 63.11562 What are my initial compliance requirements? (a) For asphalt processing operations, you must: (1) Demonstrate initial...

  3. 40 CFR 63.11562 - What are my initial compliance requirements?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... CATEGORIES (CONTINUED) National Emission Standards for Hazardous Air Pollutants for Area Sources: Asphalt Processing and Asphalt Roofing Manufacturing Standards and Compliance Requirements § 63.11562 What are my initial compliance requirements? (a) For asphalt processing operations, you must: (1) Demonstrate initial...

  4. 40 CFR 240.208-1 - Requirement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...-1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.208-1 Requirement. Residue and other solid waste products resulting from a thermal process shall be disposed of in an...

  5. Factory-Calibrated Continuous Glucose Sensors: The Science Behind the Technology.

    PubMed

    Hoss, Udo; Budiman, Erwin Satrya

    2017-05-01

    The use of commercially available continuous glucose monitors for diabetes management requires sensor calibrations, which until recently are exclusively performed by the patient. A new development is the implementation of factory calibration for subcutaneous glucose sensors, which eliminates the need for user calibrations and the associated blood glucose tests. Factory calibration means that the calibration process is part of the sensor manufacturing process and performed under controlled laboratory conditions. The ability to move from a user calibration to factory calibration is based on several technical requirements related to sensor stability and the robustness of the sensor manufacturing process. The main advantages of factory calibration over the conventional user calibration are: (a) more convenience for the user, since no more fingersticks are required for calibration and (b) elimination of use errors related to the execution of the calibration process, which can lead to sensor inaccuracies. The FreeStyle Libre ™ and FreeStyle Libre Pro ™ flash continuous glucose monitoring systems are the first commercially available sensor systems using factory-calibrated sensors. For these sensor systems, no user calibrations are required throughout the sensor wear duration.

  6. Factory-Calibrated Continuous Glucose Sensors: The Science Behind the Technology

    PubMed Central

    Budiman, Erwin Satrya

    2017-01-01

    Abstract The use of commercially available continuous glucose monitors for diabetes management requires sensor calibrations, which until recently are exclusively performed by the patient. A new development is the implementation of factory calibration for subcutaneous glucose sensors, which eliminates the need for user calibrations and the associated blood glucose tests. Factory calibration means that the calibration process is part of the sensor manufacturing process and performed under controlled laboratory conditions. The ability to move from a user calibration to factory calibration is based on several technical requirements related to sensor stability and the robustness of the sensor manufacturing process. The main advantages of factory calibration over the conventional user calibration are: (a) more convenience for the user, since no more fingersticks are required for calibration and (b) elimination of use errors related to the execution of the calibration process, which can lead to sensor inaccuracies. The FreeStyle Libre™ and FreeStyle Libre Pro™ flash continuous glucose monitoring systems are the first commercially available sensor systems using factory-calibrated sensors. For these sensor systems, no user calibrations are required throughout the sensor wear duration. PMID:28541139

  7. 5 CFR 838.721 - Application requirements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... (CONTINUED) COURT ORDERS AFFECTING RETIREMENT BENEFITS Procedures for Processing Court Orders Awarding Former... former spouse survivor annuity based on a court order acceptable for processing. No special form is required to give OPM notice of the court order. (2) OPM may require an additional application after the...

  8. Voluntary Professional Credentialing Programs. A Resource Handbook for Continuing Educators.

    ERIC Educational Resources Information Center

    Hanniford, Barbara, Ed.

    This handbook describes 77 voluntary programs offering professional credentialing for people in a wide range of professional and occupational fields. Each description lists credentials, organization offering credentials, initial credentialing requirements, credential renewal requirements (if any), continuing education approval process, and other…

  9. 40 CFR 63.1511 - Performance test/compliance demonstration general requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS FOR... reactive fluxing rate. (2) Each performance test for a continuous process must consist of 3 separate runs...

  10. 40 CFR 63.8690 - How do I monitor and collect data to demonstrate continuous compliance?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... SOURCE CATEGORIES (CONTINUED) National Emission Standards for Hazardous Air Pollutants: Asphalt Processing and Asphalt Roofing Manufacturing Continuous Compliance Requirements § 63.8690 How do I monitor...

  11. 40 CFR 63.8690 - How do I monitor and collect data to demonstrate continuous compliance?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... SOURCE CATEGORIES (CONTINUED) National Emission Standards for Hazardous Air Pollutants: Asphalt Processing and Asphalt Roofing Manufacturing Continuous Compliance Requirements § 63.8690 How do I monitor...

  12. 40 CFR 63.8690 - How do I monitor and collect data to demonstrate continuous compliance?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... SOURCE CATEGORIES (CONTINUED) National Emission Standards for Hazardous Air Pollutants: Asphalt Processing and Asphalt Roofing Manufacturing Continuous Compliance Requirements § 63.8690 How do I monitor...

  13. 40 CFR 63.8690 - How do I monitor and collect data to demonstrate continuous compliance?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... SOURCE CATEGORIES (CONTINUED) National Emission Standards for Hazardous Air Pollutants: Asphalt Processing and Asphalt Roofing Manufacturing Continuous Compliance Requirements § 63.8690 How do I monitor...

  14. 40 CFR 63.1429 - Process vent monitoring requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... thermocouple, ultra-violet beam sensor, or infrared sensor) capable of continuously detecting the presence of a... used, a temperature monitoring device equipped with a continuous recorder is required. (i) Where an incinerator other than a catalytic incinerator is used, a temperature monitoring device shall be installed in...

  15. 40 CFR 63.1429 - Process vent monitoring requirements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... thermocouple, ultra-violet beam sensor, or infrared sensor) capable of continuously detecting the presence of a... used, a temperature monitoring device equipped with a continuous recorder is required. (i) Where an incinerator other than a catalytic incinerator is used, a temperature monitoring device shall be installed in...

  16. 40 CFR 63.1429 - Process vent monitoring requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... thermocouple, ultra-violet beam sensor, or infrared sensor) capable of continuously detecting the presence of a... used, a temperature monitoring device equipped with a continuous recorder is required. (i) Where an incinerator other than a catalytic incinerator is used, a temperature monitoring device shall be installed in...

  17. 32 CFR 651.47 - Public involvement.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) ENVIRONMENTAL QUALITY ENVIRONMENTAL ANALYSIS OF ARMY ACTIONS (AR 200-2) Public Involvement and the Scoping Process § 651.47 Public... analyzing environmental considerations. This requirement can be met at the very beginning of the process by...

  18. 32 CFR 651.47 - Public involvement.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) ENVIRONMENTAL QUALITY ENVIRONMENTAL ANALYSIS OF ARMY ACTIONS (AR 200-2) Public Involvement and the Scoping Process § 651.47 Public... analyzing environmental considerations. This requirement can be met at the very beginning of the process by...

  19. 32 CFR 651.47 - Public involvement.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) ENVIRONMENTAL QUALITY ENVIRONMENTAL ANALYSIS OF ARMY ACTIONS (AR 200-2) Public Involvement and the Scoping Process § 651.47 Public... analyzing environmental considerations. This requirement can be met at the very beginning of the process by...

  20. 32 CFR 651.47 - Public involvement.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) ENVIRONMENTAL QUALITY ENVIRONMENTAL ANALYSIS OF ARMY ACTIONS (AR 200-2) Public Involvement and the Scoping Process § 651.47 Public... analyzing environmental considerations. This requirement can be met at the very beginning of the process by...

  1. 40 CFR 63.1326 - Batch process vents-recordkeeping provisions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS FOR SOURCE CATEGORIES (CONTINUED) National Emission Standards for Hazardous Air Pollutant Emissions: Group IV Polymers and Resins... requirements for Group 2 batch process vents that are exempt from the batch mass input limitation provisions...

  2. 40 CFR 65.156 - General monitoring requirements for control and recovery devices.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) CONSOLIDATED FEDERAL AIR RULE Closed Vent Systems, Control Devices, and Routing to a Fuel Gas System or a Process § 65.156 General monitoring requirements for... systems. (1) All monitoring equipment shall be installed, calibrated, maintained, and operated according...

  3. 40 CFR 161.162 - Description of production process.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 25 2013-07-01 2013-07-01 false Description of production process. 161.162 Section 161.162 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS DATA REQUIREMENTS FOR REGISTRATION OF ANTIMICROBIAL PESTICIDES Product Chemistry Data Requirements...

  4. 49 CFR 266.15 - Requirements for State Rail Plan.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... DEPARTMENT OF TRANSPORTATION ACT § 266.15 Requirements for State Rail Plan. (a) State planning process. The State Rail Plan shall be based on a comprehensive, coordinated and continuing planning process for all... submitted to the Commission for approval or are in the process of negotiation, to the extent that this...

  5. 14 CFR 60.16 - Additional qualifications for a currently qualified FSTD.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... TRANSPORTATION (CONTINUED) AIRMEN FLIGHT SIMULATION TRAINING DEVICE INITIAL AND CONTINUING QUALIFICATION AND USE... required to undergo an additional qualification process if a user intends to use the FSTD for meeting... that FSTD. This process consists of the following: (1) The sponsor: (i) Must submit to the NSPM all...

  6. Certification renewal process of the American Board of Orthodontics.

    PubMed

    Castelein, Paul T; DeLeon, Eladio; Dugoni, Steven A; Chung, Chun-Hsi; Tadlock, Larry P; Barone, Nicholas D; Kulbersh, Valmy P; Sabott, David G; Kastrop, Marvin C

    2015-05-01

    The American Board of Orthodontics was established in 1929 and is the oldest specialty board in dentistry. Its goal is to protect the public by ensuring competency through the certification of eligible orthodontists. Originally, applicants for certification submitted a thesis, 5 case reports, and a set of casts with appliances. Once granted, the certification never expired. Requirements have changed over the years. In 1950, 15 cases were required, and then 10 in 1987. The Board has continued to refine and improve the certification process. In 1998, certification became time limited, and a renewal process was initiated. The Board continues to improve the recertification process. Copyright © 2015 American Association of Orthodontists. Published by Elsevier Inc. All rights reserved.

  7. 40 CFR 98.266 - Data reporting requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... wet-process phosphoric acid process lines. (8) Number of times missing data procedures were used to... 40 Protection of Environment 21 2014-07-01 2014-07-01 false Data reporting requirements. 98.266... (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Phosphoric Acid Production § 98.266 Data reporting...

  8. On the Processing of Martensitic Steels in Continuous Galvanizing Lines: Part 1

    NASA Astrophysics Data System (ADS)

    Song, Taejin; Kwak, Jaihyun; de Cooman, B. C.

    2012-01-01

    Whereas low-carbon (<0.2 mass pct) martensitic grades can be produced easily in continuous annealing processing lines equipped with the required cooling capacity, the thermal cycles in continuous galvanizing lines make it difficult to produce hot-dip Zn or Zn-alloy coated high-strength martensitic grades. This is because of the tempering processes occurring during dipping of the strip in the liquid Zn bath and, in the case of galvannealed sheet steel, the short thermal treatment required to achieve the alloying between the Zn and the steel. These short additional thermal treatments last less than 30 seconds but severely degrade the mechanical properties. Using a combination of internal friction, X-ray diffraction, and transmission electron microscopy, it is shown that the ultrafine-grained lath microstructure allows for a rapid dislocation recovery and carbide formation during the galvanizing processes. In addition, the effective dislocation pinning occurring during the galvannealing process results in strain localization and the suppression of strain hardening.

  9. Adapting viral safety assurance strategies to continuous processing of biological products.

    PubMed

    Johnson, Sarah A; Brown, Matthew R; Lute, Scott C; Brorson, Kurt A

    2017-01-01

    There has been a recent drive in commercial large-scale production of biotechnology products to convert current batch mode processing to continuous processing manufacturing. There have been reports of model systems capable of adapting and linking upstream and downstream technologies into a continuous manufacturing pipeline. However, in many of these proposed continuous processing model systems, viral safety has not been comprehensively addressed. Viral safety and detection is a highly important and often expensive regulatory requirement for any new biological product. To ensure success in the adaption of continuous processing to large-scale production, there is a need to consider the development of approaches that allow for seamless incorporation of viral testing and clearance/inactivation methods. In this review, we outline potential strategies to apply current viral testing and clearance/inactivation technologies to continuous processing, as well as modifications of existing unit operations to ensure the successful integration of viral clearance into the continuous processing of biological products. Biotechnol. Bioeng. 2017;114: 21-32. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  10. 40 CFR 63.7938 - How do I demonstrate continuous compliance with the general standards?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Remediation General Compliance Requirements § 63.7938 How do I demonstrate continuous compliance with the....7893. (2) If the remediation material treated or managed by the process vented through the affected... required in § 63.7885(c)(2) to show that the total VOHAP concentration of the remediation material remains...

  11. 40 CFR 63.7565 - What parts of the General Provisions apply to me?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS FOR SOURCE CATEGORIES (CONTINUED) National Emission Standards for Hazardous Air Pollutants for Industrial, Commercial, and Institutional Boilers and Process Heaters Other Requirements and Information § 63.7565 What parts...

  12. 31 CFR 357.29 - Time required for processing transaction request.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 31 Money and Finance:Treasury 2 2013-07-01 2013-07-01 false Time required for processing transaction request. 357.29 Section 357.29 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL SERVICE, DEPARTMENT OF THE TREASURY BUREAU OF THE PUBLIC DEBT REGULATIONS...

  13. 31 CFR 357.29 - Time required for processing transaction request.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 31 Money and Finance:Treasury 2 2011-07-01 2011-07-01 false Time required for processing transaction request. 357.29 Section 357.29 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL SERVICE, DEPARTMENT OF THE TREASURY BUREAU OF THE PUBLIC DEBT REGULATIONS...

  14. 31 CFR 357.29 - Time required for processing transaction request.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 31 Money and Finance:Treasury 2 2012-07-01 2012-07-01 false Time required for processing transaction request. 357.29 Section 357.29 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL SERVICE, DEPARTMENT OF THE TREASURY BUREAU OF THE PUBLIC DEBT REGULATIONS...

  15. 31 CFR 357.29 - Time required for processing transaction request.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 31 Money and Finance: Treasury 2 2014-07-01 2014-07-01 false Time required for processing transaction request. 357.29 Section 357.29 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL SERVICE, DEPARTMENT OF THE TREASURY BUREAU OF THE FISCAL SERVICE REGULATIONS...

  16. 40 CFR 63.7892 - What are my inspection and monitoring requirements for process vents?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 14 2014-07-01 2014-07-01 false What are my inspection and monitoring requirements for process vents? 63.7892 Section 63.7892 Protection of Environment ENVIRONMENTAL PROTECTION... SOURCE CATEGORIES (CONTINUED) National Emission Standards for Hazardous Air Pollutants: Site Remediation...

  17. 40 CFR 63.7892 - What are my inspection and monitoring requirements for process vents?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 13 2011-07-01 2011-07-01 false What are my inspection and monitoring requirements for process vents? 63.7892 Section 63.7892 Protection of Environment ENVIRONMENTAL PROTECTION... SOURCE CATEGORIES (CONTINUED) National Emission Standards for Hazardous Air Pollutants: Site Remediation...

  18. 40 CFR 63.7892 - What are my inspection and monitoring requirements for process vents?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 14 2012-07-01 2011-07-01 true What are my inspection and monitoring requirements for process vents? 63.7892 Section 63.7892 Protection of Environment ENVIRONMENTAL PROTECTION... SOURCE CATEGORIES (CONTINUED) National Emission Standards for Hazardous Air Pollutants: Site Remediation...

  19. 40 CFR 63.7892 - What are my inspection and monitoring requirements for process vents?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 13 2010-07-01 2010-07-01 false What are my inspection and monitoring requirements for process vents? 63.7892 Section 63.7892 Protection of Environment ENVIRONMENTAL PROTECTION... SOURCE CATEGORIES (CONTINUED) National Emission Standards for Hazardous Air Pollutants: Site Remediation...

  20. 40 CFR 63.7892 - What are my inspection and monitoring requirements for process vents?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 14 2013-07-01 2013-07-01 false What are my inspection and monitoring requirements for process vents? 63.7892 Section 63.7892 Protection of Environment ENVIRONMENTAL PROTECTION... SOURCE CATEGORIES (CONTINUED) National Emission Standards for Hazardous Air Pollutants: Site Remediation...

  1. 10 CFR 51.26 - Requirement to publish notice of intent and conduct scoping process.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 2 2013-01-01 2013-01-01 false Requirement to publish notice of intent and conduct scoping process. 51.26 Section 51.26 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) ENVIRONMENTAL PROTECTION REGULATIONS FOR DOMESTIC LICENSING AND RELATED REGULATORY FUNCTIONS National Environmental Policy...

  2. 48 CFR 246.870-2 - Policy.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... requirements. (10) Process for keeping continually informed of current counterfeiting information and trends. (11) Process for screening the Government-Industry Data Exchange Program (GIDEP) reports and other...

  3. Process' standardization and change management in higher education. The case of TEI of Athens

    NASA Astrophysics Data System (ADS)

    Chalaris, Ioannis; Chalaris, Manolis; Gritzalis, Stefanos; Belsis, Petros

    2015-02-01

    The establishment of mature operational procedures and the effort of standardizing and certifying these procedures is a particularly arduous and demanding task which requires strong commitment from management to the existing objectives, administrative stability and continuity, availability of resources, an adequate implementation team with support from all stakeholders and of course great tolerance until tangible results of the investment are shown. Ensuring these conditions, particularly in times of economic crisis, is an extremely difficult task for large organizations such as TEI of Athens where there is heterogeneity in personnel and changes in the administrative hierarchy arise plethora of additional difficulties and require an effective change management. In this work we depict the path of standardization and certification of administrative functions of TEI of Athens, with emphasis on difficulties encountered and how to address them and in particular issues of change management and the culture related to this effort. The requirement for infrastructure needed to be maintained in processes and tools process & strategic management is embodied, in order to evolve mechanisms for continuous improvement processes and storage / recovery of the resulting knowledge. The work concludes with a general design of a road map of internal audit and continuous improvement processes for a large institution of higher education.

  4. 40 CFR 240.205-1 - Requirement.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Requirement. 240.205-1 Section 240.205-1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.205-1 Requirement...

  5. 40 CFR 240.200-1 - Requirement.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Requirement. 240.200-1 Section 240.200-1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.200-1 Requirement...

  6. 40 CFR 240.211-1 - Requirement.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Requirement. 240.211-1 Section 240.211-1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.211-1 Requirement...

  7. 40 CFR 240.208-1 - Requirement.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Requirement. 240.208-1 Section 240.208-1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.208-1 Requirement...

  8. 40 CFR 240.200-1 - Requirement.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Requirement. 240.200-1 Section 240.200-1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.200-1 Requirement...

  9. 40 CFR 240.208-1 - Requirement.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Requirement. 240.208-1 Section 240.208-1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.208-1 Requirement...

  10. 40 CFR 240.206-1 - Requirement.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Requirement. 240.206-1 Section 240.206-1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.206-1 Requirement...

  11. 40 CFR 240.211-1 - Requirement.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Requirement. 240.211-1 Section 240.211-1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.211-1 Requirement...

  12. 40 CFR 240.206-1 - Requirement.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Requirement. 240.206-1 Section 240.206-1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.206-1 Requirement...

  13. 40 CFR 240.208-1 - Requirement.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Requirement. 240.208-1 Section 240.208-1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.208-1 Requirement...

  14. 40 CFR 240.202-1 - Requirement.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Requirement. 240.202-1 Section 240.202-1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.202-1 Requirement...

  15. 40 CFR 240.204-1 - Requirement.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Requirement. 240.204-1 Section 240.204-1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.204-1 Requirement...

  16. 40 CFR 240.204-1 - Requirement.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Requirement. 240.204-1 Section 240.204-1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.204-1 Requirement...

  17. 40 CFR 240.204-1 - Requirement.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Requirement. 240.204-1 Section 240.204-1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.204-1 Requirement...

  18. 40 CFR 240.203-1 - Requirement.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Requirement. 240.203-1 Section 240.203-1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.203-1 Requirement...

  19. 40 CFR 240.203-1 - Requirement.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Requirement. 240.203-1 Section 240.203-1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.203-1 Requirement...

  20. 40 CFR 240.207-1 - Requirement.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Requirement. 240.207-1 Section 240.207-1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.207-1 Requirement...

  1. 40 CFR 240.211-1 - Requirement.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Requirement. 240.211-1 Section 240.211-1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.211-1 Requirement...

  2. 40 CFR 240.205-1 - Requirement.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Requirement. 240.205-1 Section 240.205-1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.205-1 Requirement...

  3. 40 CFR 240.202-1 - Requirement.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Requirement. 240.202-1 Section 240.202-1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.202-1 Requirement...

  4. 40 CFR 240.205-1 - Requirement.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Requirement. 240.205-1 Section 240.205-1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.205-1 Requirement...

  5. 40 CFR 240.207-1 - Requirement.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Requirement. 240.207-1 Section 240.207-1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.207-1 Requirement...

  6. 40 CFR 240.203-1 - Requirement.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Requirement. 240.203-1 Section 240.203-1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.203-1 Requirement...

  7. 40 CFR 240.207-1 - Requirement.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Requirement. 240.207-1 Section 240.207-1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.207-1 Requirement...

  8. 40 CFR 240.206-1 - Requirement.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Requirement. 240.206-1 Section 240.206-1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.206-1 Requirement...

  9. 40 CFR 240.210-1 - Requirement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Requirement. 240.210-1 Section 240.210-1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.210-1 Requirement...

  10. 40 CFR 240.202-1 - Requirement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Requirement. 240.202-1 Section 240.202-1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.202-1 Requirement...

  11. 40 CFR 240.207-1 - Requirement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Requirement. 240.207-1 Section 240.207-1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.207-1 Requirement...

  12. 40 CFR 240.211-1 - Requirement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Requirement. 240.211-1 Section 240.211-1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.211-1 Requirement...

  13. 40 CFR 240.204-1 - Requirement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Requirement. 240.204-1 Section 240.204-1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.204-1 Requirement...

  14. 40 CFR 240.203-1 - Requirement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Requirement. 240.203-1 Section 240.203-1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.203-1 Requirement...

  15. 40 CFR 240.205-1 - Requirement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Requirement. 240.205-1 Section 240.205-1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.205-1 Requirement...

  16. 40 CFR 240.206-1 - Requirement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Requirement. 240.206-1 Section 240.206-1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.206-1 Requirement...

  17. 40 CFR 240.202-1 - Requirement.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Requirement. 240.202-1 Section 240.202-1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.202-1 Requirement...

  18. Regulatory and quality considerations for continuous manufacturing. May 20-21, 2014 Continuous Manufacturing Symposium.

    PubMed

    Allison, Gretchen; Cain, Yanxi Tan; Cooney, Charles; Garcia, Tom; Bizjak, Tara Gooen; Holte, Oyvind; Jagota, Nirdosh; Komas, Bekki; Korakianiti, Evdokia; Kourti, Dora; Madurawe, Rapti; Morefield, Elaine; Montgomery, Frank; Nasr, Moheb; Randolph, William; Robert, Jean-Louis; Rudd, Dave; Zezza, Diane

    2015-03-01

    This paper assesses the current regulatory environment, relevant regulations and guidelines, and their impact on continuous manufacturing. It summarizes current regulatory experience and learning from both review and inspection perspectives. It outlines key regulatory aspects, including continuous manufacturing process description and control strategy in regulatory files, process validation, and key Good Manufacturing Practice (GMP) requirements. In addition, the paper identifies regulatory gaps and challenges and proposes a way forward to facilitate implementation. © 2014 Wiley Periodicals, Inc. and the American Pharmacists Association.

  19. 40 CFR 240.200-1 - Requirement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...-1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.200-1 Requirement. In consultation with the responsible agencies, the owner/operator shall determine what wastes shall...

  20. 40 CFR 240.200-1 - Requirement.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...-1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.200-1 Requirement. In consultation with the responsible agencies, the owner/operator shall determine what wastes shall...

  1. Design of launch systems using continuous improvement process

    NASA Technical Reports Server (NTRS)

    Brown, Richard W.

    1995-01-01

    The purpose of this paper is to identify a systematic process for improving ground operations for future launch systems. This approach is based on the Total Quality Management (TQM) continuous improvement process. While the continuous improvement process is normally identified with making incremental changes to an existing system, it can be used on new systems if they use past experience as a knowledge base. In the case of the Reusable Launch Vehicle (RLV), the Space Shuttle operations provide many lessons. The TQM methodology used for this paper will be borrowed from the United States Air Force 'Quality Air Force' Program. There is a general overview of the continuous improvement process, with concentration on the formulation phase. During this phase critical analyses are conducted to determine the strategy and goals for the remaining development process. These analyses include analyzing the mission from the customers point of view, developing an operations concept for the future, assessing current capabilities and determining the gap to be closed between current capabilities and future needs and requirements. A brief analyses of the RLV, relative to the Space Shuttle, will be used to illustrate the concept. Using the continuous improvement design concept has many advantages. These include a customer oriented process which will develop a more marketable product and a better integration of operations and systems during the design phase. But, the use of TQM techniques will require changes, including more discipline in the design process and more emphasis on data gathering for operational systems. The benefits will far outweigh the additional effort.

  2. 42 CFR 460.12 - Application requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... (CONTINUED) PROGRAMS OF ALL-INCLUSIVE CARE FOR THE ELDERLY (PACE) PROGRAMS OF ALL-INCLUSIVE CARE FOR THE ELDERLY (PACE) PACE Organization Application and Waiver Process § 460.12 Application requirements. (a...

  3. 42 CFR 460.12 - Application requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... (CONTINUED) PROGRAMS OF ALL-INCLUSIVE CARE FOR THE ELDERLY (PACE) PROGRAMS OF ALL-INCLUSIVE CARE FOR THE ELDERLY (PACE) PACE Organization Application and Waiver Process § 460.12 Application requirements. (a...

  4. Process Improvements in Training Device Acceptance Testing: A Study in Total Quality Management

    DTIC Science & Technology

    1990-12-12

    Quality Management , a small group of Government and industry specialists examined the existing training device acceptance test process for potential improvements. The agreed-to mission of the Air Force/Industry partnership was to continuously identify and promote implementable approaches to minimize the cost and time required for acceptance testing while ensuring that validated performance supports the user training requirements. Application of a Total Quality process improvement model focused on the customers and their requirements, analyzed how work was accomplished, and

  5. Texas Solar Collaboration Action Plan

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Winland, Chris

    2013-02-14

    Texas Solar Collaboration Permitting and Interconenction Process Improvement Action Plan. San Antonio-specific; Investigate feasibility of using electronic signatures; Investigate feasibility of enabling other online permitting processes (e.g., commercial); Assess need for future document management and workflow/notification IT improvements; Update Information Bulletin 153 regarding City requirements and processes for PV; Educate contractors and public on CPS Energy’s new 2013 solar program processes; Continue to discuss “downtown grid” interconnection issues and identify potential solutions; Consider renaming Distributed Energy Resources (DER); and Continue to participate in collaborative actions.

  6. 40 CFR 240.201-1 - Requirement.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...-1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.201-1 Requirement. Using information provided to them by the waste generator/owner, the responsible agency and the facility...

  7. 40 CFR 63.1429 - Process vent monitoring requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... the presence of a pilot flame. (3) Where a boiler or process heater of less than 44 megawatts design... series are used, a scrubbing liquid flow rate meter, or a pressure monitoring device, equipped with a continuous recorder, is required for each absorber in the series. An owner or operator may submit a request...

  8. 40 CFR 63.1429 - Process vent monitoring requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... the presence of a pilot flame. (3) Where a boiler or process heater of less than 44 megawatts design... series are used, a scrubbing liquid flow rate meter, or a pressure monitoring device, equipped with a continuous recorder, is required for each absorber in the series. An owner or operator may submit a request...

  9. 40 CFR 63.2450 - What are my general requirements for complying with this subpart?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... values are available for at least two of the 15-minute periods during an hour when calibration, quality... during periods of startup, shutdown, and malfunction (SSM), and you must meet the requirements specified...., continuous process vents, batch process vents, storage tanks, transfer operations, and waste management units...

  10. 40 CFR 63.2450 - What are my general requirements for complying with this subpart?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... values are available for at least two of the 15-minute periods during an hour when calibration, quality..., except during periods of startup, shutdown, and malfunction (SSM), and you must meet the requirements...., continuous process vents, batch process vents, storage tanks, transfer operations, and waste management units...

  11. 34 CFR 364.50 - What requirements apply to the processing of referrals and applications?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 34 Education 2 2011-07-01 2010-07-01 true What requirements apply to the processing of referrals and applications? 364.50 Section 364.50 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND REHABILITATIVE SERVICES, DEPARTMENT OF EDUCATION STATE...

  12. 34 CFR 364.50 - What requirements apply to the processing of referrals and applications?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 2 2010-07-01 2010-07-01 false What requirements apply to the processing of referrals and applications? 364.50 Section 364.50 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND REHABILITATIVE SERVICES, DEPARTMENT OF EDUCATION STATE...

  13. 21 CFR 111.460 - What requirements apply to holding in-process material?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 2 2010-04-01 2010-04-01 false What requirements apply to holding in-process material? 111.460 Section 111.460 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION CURRENT GOOD MANUFACTURING PRACTICE IN...

  14. 40 CFR 63.1094 - What waste streams are exempt from the requirements of this subpart?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... CATEGORIES (CONTINUED) National Emission Standards for Ethylene Manufacturing Process Units: Heat Exchange... section are exempt from this subpart. (a) Waste in the form of gases or vapors that is emitted from process fluids. (b) Waste that is contained in a segregated storm water sewer system. Waste Requirements ...

  15. Factors Influencing Team Performance in a Continuous Quality Improvement Process in the Wisconsin Technical College System

    ERIC Educational Resources Information Center

    Pietz, Victoria Lynn

    2014-01-01

    Continuous Quality Improvement (CQI) programs are growing in popularity in higher education settings and a key component is the use of work groups, which require active employee involvement. The problem addressed in this research was the lack of employee engagement in the Quality Review Process (QRP), which is a statewide CQI model developed by…

  16. A Framework for Business Process Change Requirements Analysis

    NASA Astrophysics Data System (ADS)

    Grover, Varun; Otim, Samuel

    The ability to quickly and continually adapt business processes to accommodate evolving requirements and opportunities is critical for success in competitive environments. Without appropriate linkage between redesign decisions and strategic inputs, identifying processes that need to be modified will be difficult. In this paper, we draw attention to the analysis of business process change requirements in support of process change initiatives. Business process redesign is a multifaceted phenomenon involving processes, organizational structure, management systems, human resource architecture, and many other aspects of organizational life. To be successful, the business process initiative should focus not only on identifying the processes to be redesigned, but also pay attention to various enablers of change. Above all, a framework is just a blueprint; management must lead change. We hope our modest contribution will draw attention to the broader framing of requirements for business process change.

  17. Team table: a framework and tool for continuous factory planning

    NASA Astrophysics Data System (ADS)

    Sihn, Wilfried; Bischoff, Juergen; von Briel, Ralf; Josten, Marcus

    2000-10-01

    Growing market turbulences and shorter product life cycles require a continuous adaptation of factory structures resulting in a continuous factory planning process. Therefore a new framework is developed which focuses on configuration and data management process integration. This enable an online system performance evaluation based on continuous availability of current data. The use of this framework is especially helpful and will guarantee high cost and time savings, when used in the early stages of the planning, called the concept or rough planning phase. The new framework is supported by a planning round table as a tool for team-based configuration processes integrating the knowledge of all persons involved in planning processes. A case study conducted at a German company shows the advantages which can be achieved by implementing the new framework and methods.

  18. 40 CFR 63.8685 - What are my general requirements for complying with this subpart?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... SOURCE CATEGORIES (CONTINUED) National Emission Standards for Hazardous Air Pollutants: Asphalt Processing and Asphalt Roofing Manufacturing General Compliance Requirements § 63.8685 What are my general...

  19. 40 CFR 63.8685 - What are my general requirements for complying with this subpart?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... SOURCE CATEGORIES (CONTINUED) National Emission Standards for Hazardous Air Pollutants: Asphalt Processing and Asphalt Roofing Manufacturing General Compliance Requirements § 63.8685 What are my general...

  20. 40 CFR 63.8685 - What are my general requirements for complying with this subpart?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... SOURCE CATEGORIES (CONTINUED) National Emission Standards for Hazardous Air Pollutants: Asphalt Processing and Asphalt Roofing Manufacturing General Compliance Requirements § 63.8685 What are my general...

  1. 40 CFR 63.8685 - What are my general requirements for complying with this subpart?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... SOURCE CATEGORIES (CONTINUED) National Emission Standards for Hazardous Air Pollutants: Asphalt Processing and Asphalt Roofing Manufacturing General Compliance Requirements § 63.8685 What are my general...

  2. 40 CFR 63.8685 - What are my general requirements for complying with this subpart?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... SOURCE CATEGORIES (CONTINUED) National Emission Standards for Hazardous Air Pollutants: Asphalt Processing and Asphalt Roofing Manufacturing General Compliance Requirements § 63.8685 What are my general...

  3. 40 CFR 60.5415 - How do I demonstrate continuous compliance with the standards for my gas well affected facility...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... plants? 60.5415 Section 60.5415 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... used to reduce emissions, you must demonstrate continuous compliance with the performance requirements... sudden, infrequent, and unavoidable failure of air pollution control equipment, process equipment, or a...

  4. 21 CFR 133.171 - Pasteurized process pimento cheese.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Pasteurized process pimento cheese. 133.171... (CONTINUED) FOOD FOR HUMAN CONSUMPTION CHEESES AND RELATED CHEESE PRODUCTS Requirements for Specific Standardized Cheese and Related Products § 133.171 Pasteurized process pimento cheese. Pasteurized process...

  5. 21 CFR 133.171 - Pasteurized process pimento cheese.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 2 2011-04-01 2011-04-01 false Pasteurized process pimento cheese. 133.171... (CONTINUED) FOOD FOR HUMAN CONSUMPTION CHEESES AND RELATED CHEESE PRODUCTS Requirements for Specific Standardized Cheese and Related Products § 133.171 Pasteurized process pimento cheese. Pasteurized process...

  6. 40 CFR 63.8690 - How do I monitor and collect data to demonstrate continuous compliance?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Processing and Asphalt Roofing Manufacturing Continuous Compliance Requirements § 63.8690 How do I monitor... emission or operating levels, nor may such data be used in fulfilling a minimum data availability...

  7. 40 CFR 68.1 - Scope.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) CHEMICAL ACCIDENT PREVENTION... petition process for adding or deleting substances to the list of regulated substances, the requirements..., threshold quantities, and accident prevention regulations promulgated under this part do not limit in any...

  8. Regulatory and Quality Considerations for Continuous Manufacturing May 20-21, 2014 Continuous Manufacturing Symposium.

    PubMed

    Allison, Gretchen; Cain, Yanxi Tan; Cooney, Charles; Garcia, Tom; Bizjak, Tara Gooen; Holte, Oyvind; Jagota, Nirdosh; Komas, Bekki; Korakianiti, Evdokia; Kourti, Dora; Madurawe, Rapti; Morefield, Elaine; Montgomery, Frank; Nasr, Moheb; Randolph, William; Robert, Jean-Louis; Rudd, Dave; Zezza, Diane

    2015-03-01

    This paper assesses the current regulatory environment, relevant regulations and guidelines, and their impact on continuous manufacturing. It summarizes current regulatory experience and learning from both review and inspection perspectives. It outlines key regulatory aspects, including continuous manufacturing process description and control strategy in regulatory files, process validation, and key Good Manufacturing Practice (GMP) requirements. In addition, the paper identifies regulatory gaps and challenges and proposes a way forward to facilitate implementation. © 2015 Wiley Periodicals, Inc. and the American Pharmacists Association. © 2014 Wiley Periodicals, Inc. and the American Pharmacists Association.

  9. 40 CFR 63.11935 - What CEMS and CPMS requirements must I meet to demonstrate initial and continuous compliance with...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... process vents in Table 1 or 2 to this subpart. You must meet the CPMS requirements in paragraph (c) of... parameter specified in Table 5 to this subpart for each process vent control device specified in § 63.11925(b) that is used to comply with the emission limits for process vents in Table 1 or 2 to this subpart...

  10. 40 CFR 63.11935 - What CEMS and CPMS requirements must I meet to demonstrate initial and continuous compliance with...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... process vents in Table 1 or 2 to this subpart. You must meet the CPMS requirements in paragraph (c) of... parameter specified in Table 5 to this subpart for each process vent control device specified in § 63.11925(b) that is used to comply with the emission limits for process vents in Table 1 or 2 to this subpart...

  11. 40 CFR 63.11935 - What CEMS and CPMS requirements must I meet to demonstrate initial and continuous compliance with...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... process vents in Table 1 or 2 to this subpart. You must meet the CPMS requirements in paragraph (c) of... parameter specified in Table 5 to this subpart for each process vent control device specified in § 63.11925(b) that is used to comply with the emission limits for process vents in Table 1 or 2 to this subpart...

  12. 40 CFR 63.11940 - What continuous monitoring requirements must I meet for control devices required to install CPMS...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... consistent with the manufacturer's recommendations within 15 days or by the next time any process vent stream... the manufacturer's recommendations within 15 days or by the next time any process vent stream is...) Determine gas stream flow using the design blower capacity, with appropriate adjustments for pressure drop...

  13. 40 CFR 63.1092 - What are the major differences between the requirements of 40 CFR part 61, subpart FF, and the...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... the requirements of 40 CFR part 61, subpart FF, and the waste requirements for ethylene production... (CONTINUED) National Emission Standards for Ethylene Manufacturing Process Units: Heat Exchange Systems and... requirements of 40 CFR part 61, subpart FF, and the waste requirements for ethylene production sources? The...

  14. 40 CFR 65.62 - Process vent group determination.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ..., or Group 2B) for each process vent. Group 1 process vents require control, and Group 2A and 2B... 40 Protection of Environment 15 2010-07-01 2010-07-01 false Process vent group determination. 65... (CONTINUED) CONSOLIDATED FEDERAL AIR RULE Process Vents § 65.62 Process vent group determination. (a) Group...

  15. 40 CFR 63.7570 - Who implements and enforces this subpart?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS FOR SOURCE CATEGORIES (CONTINUED) National Emission Standards for Hazardous Air Pollutants for Industrial, Commercial, and Institutional Boilers and Process Heaters Other Requirements and Information § 63.7570 Who implements and...

  16. 40 CFR 68.90 - Applicability.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) CHEMICAL ACCIDENT PREVENTION PROVISIONS Emergency Response § 68.90 Applicability. (a) Except as provided in... processes shall comply with the requirements of § 68.95. (b) The owner or operator of stationary source...

  17. Back to School: A Guide to Continuing Your Education after Prison

    ERIC Educational Resources Information Center

    Crayton, Anna; Lindahl, Nicole

    2010-01-01

    By picking up this guide, you have already taken an important step towards continuing your education. Going back to school will require hard work and dedication. The process will be both challenging and frustrating. But if you stick with it, continuing your education can bring you tremendous rewards. Earning a General Education Development…

  18. General Recommendations on Fatigue Risk Management for the Canadian Forces

    DTIC Science & Technology

    2010-04-01

    missions performed in aviation require an individual(s) to process large amount of information in a short period of time and to do this on a continuous...information processing required during sustained operations can deteriorate an individual’s ability to perform a task. Given the high operational tempo...memory, which, in turn, is utilized to perform human thought processes (Baddeley, 2003). While various versions of this theory exist, they all share

  19. 40 CFR Appendix C to Part 75 - Missing Data Estimation Procedures

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... certification of a parametric, empirical, or process simulation method or model for calculating substitute data... available process simulation methods and models. 1.2Petition Requirements Continuously monitor, determine... desulfurization, a corresponding empirical correlation or process simulation parametric method using appropriate...

  20. 40 CFR Table 6 to Subpart Lllll of... - Requirements for Reports

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... (CONTINUED) National Emission Standards for Hazardous Air Pollutants: Asphalt Processing and Asphalt Roofing Manufacturing Pt. 63, Subpt. LLLLL, Table 6 Table 6 to Subpart LLLLL of Part 63—Requirements for Reports You...

  1. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    The ''Disposal of Waste or Excess High Explosives'' project began January 1971. Various methods of disposal were investigated with the conclusion that incineration, at major ERDA facilities, would be the most feasible and safest method with the least cost and development time required. Two independent incinerator concepts were investigated: a rotary type for continuous processing and an enclosed pit type for batch processing. Both concepts are feasible; however, it is recommended that further investigations would be required to render them acceptable. It is felt that a larger effort would be required in the case of the rotary incinerator. The projectmore » was terminated (December 1976) prior to completion as a result of a grant of authority by the Texas Air Control Board allowing the ERDA Pantex Plant to continue indefinitely outdoor burning of explosives.« less

  2. 49 CFR Appendix A to Part 580 - Secure Printing Processes and Other Secure Processes

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 7 2014-10-01 2014-10-01 false Secure Printing Processes and Other Secure Processes A Appendix A to Part 580 Transportation Other Regulations Relating to Transportation (Continued... DISCLOSURE REQUIREMENTS Pt. 580, App. A Appendix A to Part 580—Secure Printing Processes and Other Secure...

  3. 49 CFR Appendix A to Part 580 - Secure Printing Processes and Other Secure Processes

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 7 2012-10-01 2012-10-01 false Secure Printing Processes and Other Secure Processes A Appendix A to Part 580 Transportation Other Regulations Relating to Transportation (Continued... DISCLOSURE REQUIREMENTS Pt. 580, App. A Appendix A to Part 580—Secure Printing Processes and Other Secure...

  4. 49 CFR Appendix A to Part 580 - Secure Printing Processes and Other Secure Processes

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 7 2011-10-01 2011-10-01 false Secure Printing Processes and Other Secure Processes A Appendix A to Part 580 Transportation Other Regulations Relating to Transportation (Continued... DISCLOSURE REQUIREMENTS Pt. 580, App. A Appendix A to Part 580—Secure Printing Processes and Other Secure...

  5. 49 CFR Appendix A to Part 580 - Secure Printing Processes and Other Secure Processes

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 7 2013-10-01 2013-10-01 false Secure Printing Processes and Other Secure Processes A Appendix A to Part 580 Transportation Other Regulations Relating to Transportation (Continued... DISCLOSURE REQUIREMENTS Pt. 580, App. A Appendix A to Part 580—Secure Printing Processes and Other Secure...

  6. 40 CFR 63.9600 - What are my operation and maintenance requirements?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... correspond to your standard operating procedures for maintaining the proper and efficient combustion within... PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS FOR SOURCE CATEGORIES (CONTINUED) National Emission Standards for Hazardous Air Pollutants: Taconite Iron Ore Processing Operation...

  7. 40 CFR 63.9600 - What are my operation and maintenance requirements?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... correspond to your standard operating procedures for maintaining the proper and efficient combustion within... PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS FOR SOURCE CATEGORIES (CONTINUED) National Emission Standards for Hazardous Air Pollutants: Taconite Iron Ore Processing Operation...

  8. 40 CFR 63.9600 - What are my operation and maintenance requirements?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... correspond to your standard operating procedures for maintaining the proper and efficient combustion within... PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS FOR SOURCE CATEGORIES (CONTINUED) National Emission Standards for Hazardous Air Pollutants: Taconite Iron Ore Processing Operation...

  9. 40 CFR 63.605 - Monitoring requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS FOR SOURCE CATEGORIES (CONTINUED) National Emission Standards for Hazardous Air Pollutants From Phosphoric Acid Manufacturing Plants § 63.605... the mass flow of phosphorus-bearing feed material to the process. The monitoring system shall have an...

  10. Hybrid Discrete-Continuous Markov Decision Processes

    NASA Technical Reports Server (NTRS)

    Feng, Zhengzhu; Dearden, Richard; Meuleau, Nicholas; Washington, Rich

    2003-01-01

    This paper proposes a Markov decision process (MDP) model that features both discrete and continuous state variables. We extend previous work by Boyan and Littman on the mono-dimensional time-dependent MDP to multiple dimensions. We present the principle of lazy discretization, and piecewise constant and linear approximations of the model. Having to deal with several continuous dimensions raises several new problems that require new solutions. In the (piecewise) linear case, we use techniques from partially- observable MDPs (POMDPS) to represent value functions as sets of linear functions attached to different partitions of the state space.

  11. 33 CFR 148.107 - What additional information may be required?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... HOMELAND SECURITY (CONTINUED) DEEPWATER PORTS DEEPWATER PORTS: GENERAL Application for a License § 148.107...), in coordination with MARAD, may determine whether compliance with the requirement is important to processing the application within the time prescribed by the Act. (3) If the requirement is important to...

  12. Statistical Methods in Assembly Quality Management of Multi-Element Products on Automatic Rotor Lines

    NASA Astrophysics Data System (ADS)

    Pries, V. V.; Proskuriakov, N. E.

    2018-04-01

    To control the assembly quality of multi-element mass-produced products on automatic rotor lines, control methods with operational feedback are required. However, due to possible failures in the operation of the devices and systems of automatic rotor line, there is always a real probability of getting defective (incomplete) products into the output process stream. Therefore, a continuous sampling control of the products completeness, based on the use of statistical methods, remains an important element in managing the quality of assembly of multi-element mass products on automatic rotor lines. The feature of continuous sampling control of the multi-element products completeness in the assembly process is its breaking sort, which excludes the possibility of returning component parts after sampling control to the process stream and leads to a decrease in the actual productivity of the assembly equipment. Therefore, the use of statistical procedures for continuous sampling control of the multi-element products completeness when assembled on automatic rotor lines requires the use of such sampling plans that ensure a minimum size of control samples. Comparison of the values of the limit of the average output defect level for the continuous sampling plan (CSP) and for the automated continuous sampling plan (ACSP) shows the possibility of providing lower limit values for the average output defects level using the ACSP-1. Also, the average sample size when using the ACSP-1 plan is less than when using the CSP-1 plan. Thus, the application of statistical methods in the assembly quality management of multi-element products on automatic rotor lines, involving the use of proposed plans and methods for continuous selective control, will allow to automating sampling control procedures and the required level of quality of assembled products while minimizing sample size.

  13. 40 CFR 158.330 - Description of production process.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Description of production process. 158.330 Section 158.330 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS DATA REQUIREMENTS FOR PESTICIDES Product Chemistry § 158.330 Description of production process. If...

  14. 40 CFR 158.330 - Description of production process.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 24 2014-07-01 2014-07-01 false Description of production process. 158.330 Section 158.330 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS DATA REQUIREMENTS FOR PESTICIDES Product Chemistry § 158.330 Description of production process. If...

  15. 40 CFR 158.330 - Description of production process.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 25 2012-07-01 2012-07-01 false Description of production process. 158.330 Section 158.330 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS DATA REQUIREMENTS FOR PESTICIDES Product Chemistry § 158.330 Description of production process. If...

  16. 40 CFR 158.330 - Description of production process.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 24 2011-07-01 2011-07-01 false Description of production process. 158.330 Section 158.330 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS DATA REQUIREMENTS FOR PESTICIDES Product Chemistry § 158.330 Description of production process. If...

  17. 40 CFR 158.330 - Description of production process.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 25 2013-07-01 2013-07-01 false Description of production process. 158.330 Section 158.330 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS DATA REQUIREMENTS FOR PESTICIDES Product Chemistry § 158.330 Description of production process. If...

  18. 40 CFR Table 9 to Subpart Ddddd of... - Reporting Requirements

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS FOR SOURCE CATEGORIES (CONTINUED) National Emission Standards for Hazardous Air Pollutants for Industrial, Commercial, and Institutional Boilers and Process Heaters Pt. 63, Subpt. DDDDD, Table 9 Table 9 to Subpart DDDDD of Part 63...

  19. Wisconsin Recertification Manual for Public Librarians.

    ERIC Educational Resources Information Center

    Fox, Robert; And Others

    Designed to assist public librarians certified after May 1, 1979, this manual explains Wisconsin recertification requirements based on continuing education. It provides continuing education guidelines, a flow chart of the recertification process, an individual learning activity form, an annual report form, a conversion chart for assignment of…

  20. Aspects of the BPRIM Language for Risk Driven Process Engineering

    NASA Astrophysics Data System (ADS)

    Sienou, Amadou; Lamine, Elyes; Pingaud, Hervé; Karduck, Achim

    Nowadays organizations are exposed to frequent changes in business environment requiring continuous alignment of business processes on business strategies. This agility requires methods promoted in enterprise engineering approaches. Risk consideration in enterprise engineering is getting important since the business environment is becoming more and more competitive and unpredictable. Business processes are subject to the same quality requirements as material and human resources. Thus, process management is supposed to tackle value creation challenges but also the ones related to value preservation. Our research considers risk driven business process design as an integral part of enterprise engineering. A graphical modelling language for risk driven business process engineering was introduced in former research. This paper extends the language and handles questions related to modelling risk in organisational context.

  1. 32 CFR 807.5 - Processing requests.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 6 2010-07-01 2010-07-01 false Processing requests. 807.5 Section 807.5 National Defense Department of Defense (Continued) DEPARTMENT OF THE AIR FORCE ADMINISTRATION SALE TO THE PUBLIC § 807.5 Processing requests. Payment is required before shipping the requested material. Payment...

  2. 21 CFR 133.179 - Pasteurized process cheese spread.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 2 2011-04-01 2011-04-01 false Pasteurized process cheese spread. 133.179 Section... (CONTINUED) FOOD FOR HUMAN CONSUMPTION CHEESES AND RELATED CHEESE PRODUCTS Requirements for Specific Standardized Cheese and Related Products § 133.179 Pasteurized process cheese spread. (a)(1) Pasteurized...

  3. Process Makes Thermoplastic Prepreg Ribbon

    NASA Technical Reports Server (NTRS)

    Wilson, Maywood L.; Johnson, Gary S.

    1995-01-01

    Manufacturing process produces ribbon of composite material (prepreg) consisting of continuous lengthwise fibers impregnated with thermoplastic resin. Ribbon can later be cut into sheets of required sizes and shapes, stacked, then heated under pressure to form composite-material structural components. Process accommodates variety of thermoplastic resins and variety of fibers.

  4. Interference effects of vocalization on dual task performance

    NASA Astrophysics Data System (ADS)

    Owens, J. M.; Goodman, L. S.; Pianka, M. J.

    1984-09-01

    Voice command and control systems have been proposed as a potential means of off-loading the typically overburdened visual information processing system. However, prior to introducing novel human-machine interfacing technologies in high workload environments, consideration must be given to the integration of the new technologists within existing task structures to ensure that no new sources of workload or interference are systematically introduced. This study examined the use of voice interactive systems technology in the joint performance of two cognitive information processing tasks requiring continuous memory and choice reaction wherein a basis for intertask interference might be expected. Stimuli for the continuous memory task were presented aurally and either voice or keyboard responding was required in the choice reaction task. Performance was significantly degraded in each task when voice responding was required in the choice reaction time task. Performance degradation was evident in higher error scores for both the choice reaction and continuous memory tasks. Performance decrements observed under conditions of high intertask stimulus similarity were not statistically significant. The results signal the need to consider further the task requirements for verbal short-term memory when applying speech technology in multitask environments.

  5. 21 CFR 111.90 - What requirements apply to treatments, in-process adjustments, and reprocessing when there is a...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 2 2011-04-01 2011-04-01 false What requirements apply to treatments, in-process... established in accordance with § 111.70 is not met? 111.90 Section 111.90 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION CURRENT GOOD...

  6. 42 CFR 482.100 - Condition of participation: Organ procurement.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ....100 Section 482.100 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) STANDARDS AND CERTIFICATION CONDITIONS OF PARTICIPATION FOR HOSPITALS Requirements for Specialty Hospitals Transplant Center Process Requirements § 482.100 Condition of...

  7. 40 CFR 761.372 - Specific requirements for relatively clean surfaces.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 30 2010-07-01 2010-07-01 false Specific requirements for relatively clean surfaces. 761.372 Section 761.372 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT POLYCHLORINATED BIPHENYLS (PCBs) MANUFACTURING, PROCESSING...

  8. 7 CFR 3434.10 - Reporting requirements.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 15 2013-01-01 2013-01-01 false Reporting requirements. 3434.10 Section 3434.10 Agriculture Regulations of the Department of Agriculture (Continued) NATIONAL INSTITUTE OF FOOD AND AGRICULTURE HISPANIC-SERVING AGRICULTURAL COLLEGES AND UNIVERSITIES CERTIFICATION PROCESS § 3434.10 Reporting...

  9. 7 CFR 3434.10 - Reporting requirements.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 15 2014-01-01 2014-01-01 false Reporting requirements. 3434.10 Section 3434.10 Agriculture Regulations of the Department of Agriculture (Continued) NATIONAL INSTITUTE OF FOOD AND AGRICULTURE HISPANIC-SERVING AGRICULTURAL COLLEGES AND UNIVERSITIES CERTIFICATION PROCESS § 3434.10 Reporting...

  10. 40 CFR 63.643 - Miscellaneous process vent provisions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS FOR SOURCE CATEGORIES (CONTINUED) National Emission Standards for Hazardous Air Pollutants From Petroleum Refineries § 63.643... section. (1) Reduce emissions of organic HAP's using a flare that meets the requirements of § 63.11(b) of...

  11. 40 CFR 61.357 - Reporting requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 61.357 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED... wastewater treatment system unit is monitored in accordance with § 61.354(a)(1) of this subpart, then each... unit is equal to or greater than 10 ppmw. (ii) If a treatment process or wastewater treatment system...

  12. 40 CFR 63.1324 - Batch process vents-monitoring equipment.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... beam sensor, or infrared sensor) capable of continuously detecting the presence of a pilot flame is...) Where an incinerator is used, a temperature monitoring device equipped with a continuous recorder is required. (i) Where an incinerator other than a catalytic incinerator is used, the temperature monitoring...

  13. 40 CFR 63.1324 - Batch process vents-monitoring equipment.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... beam sensor, or infrared sensor) capable of continuously detecting the presence of a pilot flame is...) Where an incinerator is used, a temperature monitoring device equipped with a continuous recorder is required. (i) Where an incinerator other than a catalytic incinerator is used, the temperature monitoring...

  14. 40 CFR 265.401 - General operating requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... equipment, the process or equipment must be equipped with a means to stop this inflow (e.g., a waste feed....401 Section 265.401 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) INTERIM STATUS STANDARDS FOR OWNERS AND OPERATORS OF HAZARDOUS WASTE TREATMENT, STORAGE, AND...

  15. 40 CFR Table 3 to Subpart Dddd of... - Work Practice Requirements

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 12 2011-07-01 2009-07-01 true Work Practice Requirements 3 Table 3 to Subpart DDDD of Part 63 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS... Table 3 to Subpart DDDD of Part 63—Work Practice Requirements For the following process units at...

  16. Incorporating assessment and prescribing for ambulatory ailments skills into practice: An environmental scan of continuing education for pharmacist prescribing in Canada

    PubMed Central

    Habicht, Dana; Ng, Sheila; Dunford, Drena; Shearer, Brenna; Kuo, I fan

    2017-01-01

    Objectives: Pharmacists in Canadian provinces are at different stages of applying prescribing legislation into practice. The purpose of this environmental scan was to examine differences in legislation, remuneration, professional uptake, continuing education requirements and continuing education resources relating to pharmacist prescribing for ambulatory ailments, with a focus on continuing education. Methods: Data were collected between May and December 2016 using websites and communication with provincial professional regulatory bodies, advocacy bodies, drug coverage programs and other organizations that offer continuing education for pharmacists. Results: Training requirements to prescribe for ambulatory ailments vary provincially, including no training requirements, online tutorials and a comprehensive application process. Government-funded remuneration for prescribing services is absent in most provinces. Pharmacist uptake of the training required to obtain prescribing authority ranges from 30% to 100% of pharmacists. Continuing education programs on the topic of prescribing across the country include online courses, in-person courses, webinars, panel discussions and preparation courses. Conclusion: Many aspects of pharmacist prescribing for ambulatory ailments, including the style and content of continuing education resources, vary from province to province. Further research on this topic would help to determine the effect of these differences on the success of incorporating pharmacist prescribing into practice. PMID:28894501

  17. Incorporating assessment and prescribing for ambulatory ailments skills into practice: An environmental scan of continuing education for pharmacist prescribing in Canada.

    PubMed

    Habicht, Dana; Ng, Sheila; Dunford, Drena; Shearer, Brenna; Kuo, I Fan

    2017-01-01

    Pharmacists in Canadian provinces are at different stages of applying prescribing legislation into practice. The purpose of this environmental scan was to examine differences in legislation, remuneration, professional uptake, continuing education requirements and continuing education resources relating to pharmacist prescribing for ambulatory ailments, with a focus on continuing education. Data were collected between May and December 2016 using websites and communication with provincial professional regulatory bodies, advocacy bodies, drug coverage programs and other organizations that offer continuing education for pharmacists. Training requirements to prescribe for ambulatory ailments vary provincially, including no training requirements, online tutorials and a comprehensive application process. Government-funded remuneration for prescribing services is absent in most provinces. Pharmacist uptake of the training required to obtain prescribing authority ranges from 30% to 100% of pharmacists. Continuing education programs on the topic of prescribing across the country include online courses, in-person courses, webinars, panel discussions and preparation courses. Many aspects of pharmacist prescribing for ambulatory ailments, including the style and content of continuing education resources, vary from province to province. Further research on this topic would help to determine the effect of these differences on the success of incorporating pharmacist prescribing into practice.

  18. 21 CFR 133.173 - Pasteurized process cheese food.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 2 2011-04-01 2011-04-01 false Pasteurized process cheese food. 133.173 Section... (CONTINUED) FOOD FOR HUMAN CONSUMPTION CHEESES AND RELATED CHEESE PRODUCTS Requirements for Specific Standardized Cheese and Related Products § 133.173 Pasteurized process cheese food. (a)(1) A pasteurized...

  19. 21 CFR 133.170 - Pasteurized process cheese with fruits, vegetables, or meats.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 2 2011-04-01 2011-04-01 false Pasteurized process cheese with fruits, vegetables... AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION CHEESES AND RELATED CHEESE PRODUCTS Requirements for Specific Standardized Cheese and Related Products § 133.170 Pasteurized process cheese with...

  20. 21 CFR 133.170 - Pasteurized process cheese with fruits, vegetables, or meats.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Pasteurized process cheese with fruits, vegetables... AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION CHEESES AND RELATED CHEESE PRODUCTS Requirements for Specific Standardized Cheese and Related Products § 133.170 Pasteurized process cheese with...

  1. 40 CFR 63.11925 - What are my initial and continuous compliance requirements for process vents?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... accepted chemical engineering principles, measurable process parameters, or physical or chemical laws or... scale. (iv) Engineering assessment including, but not limited to, the following: (A) Previous test..., and procedures used in the engineering assessment shall be documented. (3) For miscellaneous process...

  2. 40 CFR 63.11925 - What are my initial and continuous compliance requirements for process vents?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... accepted chemical engineering principles, measurable process parameters, or physical or chemical laws or... scale. (iv) Engineering assessment including, but not limited to, the following: (A) Previous test..., and procedures used in the engineering assessment shall be documented. (3) For miscellaneous process...

  3. 40 CFR 63.11925 - What are my initial and continuous compliance requirements for process vents?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... accepted chemical engineering principles, measurable process parameters, or physical or chemical laws or... scale. (iv) Engineering assessment including, but not limited to, the following: (A) Previous test..., and procedures used in the engineering assessment shall be documented. (3) For miscellaneous process...

  4. 45 CFR 1303.5 - Service of process.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 4 2010-10-01 2010-10-01 false Service of process. 1303.5 Section 1303.5 Public Welfare Regulations Relating to Public Welfare (Continued) OFFICE OF HUMAN DEVELOPMENT SERVICES... § 1303.5 Service of process. Whenever documents are required to be filed or served under this part, or...

  5. Development of a COTS Mass Storage Unit for the Space Readiness Coherent Lidar Experiment

    NASA Technical Reports Server (NTRS)

    Liggin, Karl; Clark, Porter

    1999-01-01

    The technology to develop a Mass Storage Unit (MSU) using commercial-off-the-shelf (COTS) hard drives is an on-going challenge to meet the Space Readiness Coherent Lidar Experiment (SPARCLE) program requirements. A conceptual view of SPARCLE's laser collecting atmospheric data from the shuttle is shown in Figure 1. The determination to develop this technology required several in depth studies before an actual COTS hard drive was selected to continue this effort. Continuing the development of the MSU can, and will, serve future NASA programs that require larger data storage and more on-board processing.

  6. 40 CFR 265.272 - General operating requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 25 2010-07-01 2010-07-01 false General operating requirements. 265.272 Section 265.272 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES... nonhazardous by degradation, transformation, or immobilization processes occurring in or on the soil. (b) The...

  7. 40 CFR 63.2270 - How do I monitor and collect data to demonstrate continuous compliance?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... appropriate, monitor malfunctions, associated repairs, and required quality assurance or control activities... monitoring in continuous operation at all times that the process unit is operating. For purposes of calculating data averages, you must not use data recorded during monitoring malfunctions, associated repairs...

  8. 40 CFR 63.2270 - How do I monitor and collect data to demonstrate continuous compliance?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... control activities (including, as applicable, calibration checks and required zero and span adjustments), you must conduct all monitoring in continuous operation at all times that the process unit is operating. For purposes of calculating data averages, you must not use data recorded during monitoring...

  9. 40 CFR 63.2270 - How do I monitor and collect data to demonstrate continuous compliance?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... appropriate, monitor malfunctions, associated repairs, and required quality assurance or control activities... monitoring in continuous operation at all times that the process unit is operating. For purposes of calculating data averages, you must not use data recorded during monitoring malfunctions, associated repairs...

  10. 40 CFR 63.2270 - How do I monitor and collect data to demonstrate continuous compliance?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... control activities (including, as applicable, calibration checks and required zero and span adjustments), you must conduct all monitoring in continuous operation at all times that the process unit is operating. For purposes of calculating data averages, you must not use data recorded during monitoring...

  11. 40 CFR 63.7938 - How do I demonstrate continuous compliance with the general standards?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... compliance with the general standards? 63.7938 Section 63.7938 Protection of Environment ENVIRONMENTAL... Remediation General Compliance Requirements § 63.7938 How do I demonstrate continuous compliance with the....7893. (2) If the remediation material treated or managed by the process vented through the affected...

  12. 40 CFR 63.7938 - How do I demonstrate continuous compliance with the general standards?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... compliance with the general standards? 63.7938 Section 63.7938 Protection of Environment ENVIRONMENTAL... Remediation General Compliance Requirements § 63.7938 How do I demonstrate continuous compliance with the....7893. (2) If the remediation material treated or managed by the process vented through the affected...

  13. 40 CFR 63.7938 - How do I demonstrate continuous compliance with the general standards?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... compliance with the general standards? 63.7938 Section 63.7938 Protection of Environment ENVIRONMENTAL... Remediation General Compliance Requirements § 63.7938 How do I demonstrate continuous compliance with the....7893. (2) If the remediation material treated or managed by the process vented through the affected...

  14. 40 CFR 63.7938 - How do I demonstrate continuous compliance with the general standards?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... compliance with the general standards? 63.7938 Section 63.7938 Protection of Environment ENVIRONMENTAL... Remediation General Compliance Requirements § 63.7938 How do I demonstrate continuous compliance with the....7893. (2) If the remediation material treated or managed by the process vented through the affected...

  15. 40 CFR Table 12 to Subpart G of... - Monitoring Requirements for Treatment Processes

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Appropriate methods as specified in § 63.143 and as approved by permitting authority. 2. Steam stripper (i... recorder. (ii) Wastewater feed mass flow rate; and Continuously Liquid flow meter installed at stripper... operating temperature Continuously (A) Liquid temperature monitoring device installed at stripper influent...

  16. 40 CFR Table 12 to Subpart G of... - Monitoring Requirements for Treatment Processes

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Appropriate methods as specified in § 63.143 and as approved by permitting authority. 2. Steam stripper (i... recorder. (ii) Wastewater feed mass flow rate; and Continuously Liquid flow meter installed at stripper... operating temperature Continuously (A) Liquid temperature monitoring device installed at stripper influent...

  17. 40 CFR Table 12 to Subpart G of... - Monitoring Requirements for Treatment Processes

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Appropriate methods as specified in § 63.143 and as approved by permitting authority. 2. Steam stripper (i... recorder. (ii) Wastewater feed mass flow rate; and Continuously Liquid flow meter installed at stripper... operating temperature Continuously (A) Liquid temperature monitoring device installed at stripper influent...

  18. 40 CFR Table 12 to Subpart G of... - Monitoring Requirements for Treatment Processes

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Appropriate methods as specified in § 63.143 and as approved by permitting authority. 2. Steam stripper (i... recorder. (ii) Wastewater feed mass flow rate; and Continuously Liquid flow meter installed at stripper... operating temperature Continuously (A) Liquid temperature monitoring device installed at stripper influent...

  19. 40 CFR Table 12 to Subpart G of... - Monitoring Requirements for Treatment Processes

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Appropriate methods as specified in § 63.143 and as approved by permitting authority. 2. Steam stripper (i... recorder. (ii) Wastewater feed mass flow rate; and Continuously Liquid flow meter installed at stripper... operating temperature Continuously (A) Liquid temperature monitoring device installed at stripper influent...

  20. 21 CFR 179.26 - Ionizing radiation for the treatment of food.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION (CONTINUED) IRRADIATION IN THE PRODUCTION, PROCESSING AND... “Treated by irradiation” in addition to information required by other regulations. The logo shall be placed... statement that discloses that a food has been intentionally subject to irradiation. (2) For irradiated foods...

  1. 21 CFR 179.26 - Ionizing radiation for the treatment of food.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION (CONTINUED) IRRADIATION IN THE PRODUCTION, PROCESSING AND... “Treated by irradiation” in addition to information required by other regulations. The logo shall be placed... statement that discloses that a food has been intentionally subject to irradiation. (2) For irradiated foods...

  2. 21 CFR 179.26 - Ionizing radiation for the treatment of food.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION (CONTINUED) IRRADIATION IN THE PRODUCTION, PROCESSING AND... “Treated by irradiation” in addition to information required by other regulations. The logo shall be placed... statement that discloses that a food has been intentionally subject to irradiation. (2) For irradiated foods...

  3. 21 CFR 179.26 - Ionizing radiation for the treatment of food.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION (CONTINUED) IRRADIATION IN THE PRODUCTION, PROCESSING AND... “Treated by irradiation” in addition to information required by other regulations. The logo shall be placed... statement that discloses that a food has been intentionally subject to irradiation. (2) For irradiated foods...

  4. Hot-melt co-extrusion: requirements, challenges and opportunities for pharmaceutical applications.

    PubMed

    Vynckier, An-Katrien; Dierickx, Lien; Voorspoels, Jody; Gonnissen, Yves; Remon, Jean Paul; Vervaet, Chris

    2014-02-01

    Co-extrusion implies the simultaneous hot-melt extrusion of two or more materials through the same die, creating a multi-layered extrudate. It is an innovative continuous production technology that offers numerous advantages over traditional pharmaceutical processing techniques. This review provides an overview of the co-extrusion equipment, material requirements and medical and pharmaceutical applications. The co-extrusion equipment needed for pharmaceutical production has been summarized. Because the geometrical design of the die dictates the shape of the final product, different die types have been discussed. As one of the major challenges at the moment is shaping the final product in a continuous way, an overview of downstream solutions for processing co-extrudates into drug products is provided. Layer adhesion, extrusion temperature and viscosity matching are pointed out as most important requirements for material selection. Examples of medical and pharmaceutical applications are presented and some recent findings considering the production of oral drug delivery systems have been summarized. Co-extrusion provides great potential for the continuous production of fixed-dose combination products which are gaining importance in pharmaceutical industry. There are still some barriers to the implementation of co-extrusion in the pharmaceutical industry. The optimization of downstream processing remains a point of attention. © 2013 Royal Pharmaceutical Society.

  5. 40 CFR 63.8680 - What is the purpose of this subpart?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... (CONTINUED) National Emission Standards for Hazardous Air Pollutants: Asphalt Processing and Asphalt Roofing... national emission standards for hazardous air pollutants (NESHAP) for existing and new asphalt processing and asphalt roofing manufacturing facilities. This subpart also establishes requirements to...

  6. 40 CFR 63.8680 - What is the purpose of this subpart?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... (CONTINUED) National Emission Standards for Hazardous Air Pollutants: Asphalt Processing and Asphalt Roofing... national emission standards for hazardous air pollutants (NESHAP) for existing and new asphalt processing and asphalt roofing manufacturing facilities. This subpart also establishes requirements to...

  7. 40 CFR 63.8680 - What is the purpose of this subpart?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... (CONTINUED) National Emission Standards for Hazardous Air Pollutants: Asphalt Processing and Asphalt Roofing... national emission standards for hazardous air pollutants (NESHAP) for existing and new asphalt processing and asphalt roofing manufacturing facilities. This subpart also establishes requirements to...

  8. 40 CFR 63.8680 - What is the purpose of this subpart?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... (CONTINUED) National Emission Standards for Hazardous Air Pollutants: Asphalt Processing and Asphalt Roofing... national emission standards for hazardous air pollutants (NESHAP) for existing and new asphalt processing and asphalt roofing manufacturing facilities. This subpart also establishes requirements to...

  9. 40 CFR 161.165 - Description of formulation process.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 25 2013-07-01 2013-07-01 false Description of formulation process. 161.165 Section 161.165 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS DATA REQUIREMENTS FOR REGISTRATION OF ANTIMICROBIAL PESTICIDES Product Chemistry Data...

  10. 40 CFR 161.165 - Description of formulation process.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 24 2011-07-01 2011-07-01 false Description of formulation process. 161.165 Section 161.165 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS DATA REQUIREMENTS FOR REGISTRATION OF ANTIMICROBIAL PESTICIDES Product Chemistry Data...

  11. 40 CFR 161.165 - Description of formulation process.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Description of formulation process. 161.165 Section 161.165 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS DATA REQUIREMENTS FOR REGISTRATION OF ANTIMICROBIAL PESTICIDES Product Chemistry Data...

  12. Course Development Cycle Time: A Framework for Continuous Process Improvement.

    ERIC Educational Resources Information Center

    Lake, Erinn

    2003-01-01

    Details Edinboro University's efforts to reduce the extended cycle time required to develop new courses and programs. Describes a collaborative process improvement framework, illustrated data findings, the team's recommendations for improvement, and the outcomes of those recommendations. (EV)

  13. A continuous process for the development of Kodak Aerochrome Infrared Film 2443 as a negative

    NASA Astrophysics Data System (ADS)

    Klimes, D.; Ross, D. I.

    1993-02-01

    A process for the continuous dry-to-dry development of Kodak Aerochrome Infrared Film 2443 as a negative (CIR-neg) is described. The process is well suited for production processing of long film lengths. Chemicals from three commercial film processes are used with modifications. Sensitometric procedures are recommended for the monitoring of processing quality control. Sensitometric data and operational aerial exposures indicate that films developed in this process have approximately the same effective aerial film speed as films processed in the reversal process recommended by the manufacturer (Kodak EA-5). The CIR-neg process is useful when aerial photography is acquired for resources management applications which require print reproductions. Originals can be readily reproduced using conventional production equipment (electronic dodging) in black and white or color (color compensation).

  14. 40 CFR 98.76 - Data reporting requirements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Ammonia Manufacturing § 98.76 Data reporting requirements. In... specified in paragraphs (a) and (b) of this section, as applicable for each ammonia manufacturing process... paragraph (a): (1) Annual quantity of each type of feedstock consumed for ammonia manufacturing (scf of...

  15. 40 CFR 98.76 - Data reporting requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Ammonia Manufacturing § 98.76 Data reporting requirements. In... specified in paragraphs (a) and (b) of this section, as applicable for each ammonia manufacturing process... paragraph (a): (1) Annual quantity of each type of feedstock consumed for ammonia manufacturing (scf of...

  16. 40 CFR 98.76 - Data reporting requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Ammonia Manufacturing § 98.76 Data reporting requirements. In... specified in paragraphs (a) and (b) of this section, as applicable for each ammonia manufacturing process... (2) of this section: (1) Annual quantity of each type of feedstock consumed for ammonia manufacturing...

  17. 40 CFR 98.76 - Data reporting requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Ammonia Manufacturing § 98.76 Data reporting requirements. In... specified in paragraphs (a) and (b) of this section, as applicable for each ammonia manufacturing process... this paragraph (a): (1) Annual quantity of each type of feedstock consumed for ammonia manufacturing...

  18. 40 CFR 98.76 - Data reporting requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Ammonia Manufacturing § 98.76 Data reporting requirements. In... specified in paragraphs (a) and (b) of this section, as applicable for each ammonia manufacturing process... paragraph (a): (1) Annual quantity of each type of feedstock consumed for ammonia manufacturing (scf of...

  19. 42 CFR 431.152 - State plan requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 4 2011-10-01 2011-10-01 false State plan requirements. 431.152 Section 431.152 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS STATE ORGANIZATION AND GENERAL ADMINISTRATION Appeals Process for NFs...

  20. 42 CFR 431.152 - State plan requirements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 4 2012-10-01 2012-10-01 false State plan requirements. 431.152 Section 431.152 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS STATE ORGANIZATION AND GENERAL ADMINISTRATION Appeals Process for NFs...

  1. 42 CFR 431.152 - State plan requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false State plan requirements. 431.152 Section 431.152 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS STATE ORGANIZATION AND GENERAL ADMINISTRATION Appeals Process for NFs...

  2. 42 CFR 431.152 - State plan requirements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 4 2014-10-01 2014-10-01 false State plan requirements. 431.152 Section 431.152 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS STATE ORGANIZATION AND GENERAL ADMINISTRATION Appeals Process for NFs...

  3. 42 CFR 431.152 - State plan requirements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 4 2013-10-01 2013-10-01 false State plan requirements. 431.152 Section 431.152 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS STATE ORGANIZATION AND GENERAL ADMINISTRATION Appeals Process for NFs...

  4. 40 CFR 98.164 - Monitoring and QA/QC requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Hydrogen Production § 98.164 Monitoring and QA/QC requirements. The GHG emissions data for hydrogen production process units must be quality-assured as specified in... Instrumental Determination of Carbon, Hydrogen, and Nitrogen in Petroleum Products and Lubricants (incorporated...

  5. 40 CFR 98.266 - Data reporting requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... phosphoric acid process lines. (8) Number of times missing data procedures were used to estimate phosphate... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Data reporting requirements. 98.266... (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Phosphoric Acid Production § 98.266 Data reporting...

  6. 47 CFR 54.642 - Competitive bidding requirement and exemptions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... SERVICES (CONTINUED) UNIVERSAL SERVICE Universal Service Support for Health Care Providers Healthcare... process. (1) All entities participating in the Healthcare Connect Fund must conduct a fair and open... local requirements. (c) Cost-effective. For purposes of the Healthcare Connect Fund, “cost-effective” is...

  7. 47 CFR 54.642 - Competitive bidding requirement and exemptions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... SERVICES (CONTINUED) UNIVERSAL SERVICE Universal Service Support for Health Care Providers Healthcare... process. (1) All entities participating in the Healthcare Connect Fund must conduct a fair and open... local requirements. (c) Cost-effective. For purposes of the Healthcare Connect Fund, “cost-effective” is...

  8. Feasibility of using continuous chromatography in downstream processing: Comparison of costs and product quality for a hybrid process vs. a conventional batch process.

    PubMed

    Ötes, Ozan; Flato, Hendrik; Winderl, Johannes; Hubbuch, Jürgen; Capito, Florian

    2017-10-10

    The protein A capture step is the main cost-driver in downstream processing, with high attrition costs especially when using protein A resin not until end of resin lifetime. Here we describe a feasibility study, transferring a batch downstream process to a hybrid process, aimed at replacing batch protein A capture chromatography with a continuous capture step, while leaving the polishing steps unchanged to minimize required process adaptations compared to a batch process. 35g of antibody were purified using the hybrid approach, resulting in comparable product quality and step yield compared to the batch process. Productivity for the protein A step could be increased up to 420%, reducing buffer amounts by 30-40% and showing robustness for at least 48h continuous run time. Additionally, to enable its potential application in a clinical trial manufacturing environment cost of goods were compared for the protein A step between hybrid process and batch process, showing a 300% cost reduction, depending on processed volumes and batch cycles. Copyright © 2017 Elsevier B.V. All rights reserved.

  9. Sustaining Public Involvement in Long Range Planning Using a Stakeholder Based Process: A Case Study from Eugene-Springfield ,Oregon

    DOT National Transportation Integrated Search

    1998-09-16

    The Intermodal Surface Transportation Efficiency Act requires a proactive : public involvement process that provides complete information, timely public : notice, full public access to key decisions, and supports early and continuing : involvement of...

  10. 40 CFR 158.335 - Description of formulation process.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Description of formulation process. 158.335 Section 158.335 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS DATA REQUIREMENTS FOR PESTICIDES Product Chemistry § 158.335 Description of formulation...

  11. 40 CFR 240.204-2 - Recommended procedures: Design.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ....204-2 Section 240.204-2 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures... indiscriminately. Consideration should be given to onsite treatment of process and waste waters before discharge...

  12. 40 CFR 158.335 - Description of formulation process.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 25 2013-07-01 2013-07-01 false Description of formulation process. 158.335 Section 158.335 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS DATA REQUIREMENTS FOR PESTICIDES Product Chemistry § 158.335 Description of formulation...

  13. 40 CFR 158.335 - Description of formulation process.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 24 2014-07-01 2014-07-01 false Description of formulation process. 158.335 Section 158.335 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS DATA REQUIREMENTS FOR PESTICIDES Product Chemistry § 158.335 Description of formulation...

  14. 40 CFR 158.335 - Description of formulation process.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 25 2012-07-01 2012-07-01 false Description of formulation process. 158.335 Section 158.335 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS DATA REQUIREMENTS FOR PESTICIDES Product Chemistry § 158.335 Description of formulation...

  15. 40 CFR 158.335 - Description of formulation process.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 24 2011-07-01 2011-07-01 false Description of formulation process. 158.335 Section 158.335 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS DATA REQUIREMENTS FOR PESTICIDES Product Chemistry § 158.335 Description of formulation...

  16. Modified Pressure System for Imaging Egg Cracks

    USDA-ARS?s Scientific Manuscript database

    One aspect of grading table eggs is shell checks or cracks. Currently, USDA voluntary regulations require that humans grade a representative sample of all eggs processed. However, as processing plants and packing facilities continue to increase their volume and throughput, human graders are having ...

  17. Modified Pressure System for Imaging Egg Cracks

    USDA-ARS?s Scientific Manuscript database

    Abstract One aspect of grading table eggs is shell checks or cracks. Currently, USDA voluntary regulations require that humans grade a representative sample of all eggs processed. However, as processing plants and packing facilities continue to increase their volume and throughput, human graders a...

  18. Recognition Decisions From Visual Working Memory Are Mediated by Continuous Latent Strengths.

    PubMed

    Ricker, Timothy J; Thiele, Jonathan E; Swagman, April R; Rouder, Jeffrey N

    2017-08-01

    Making recognition decisions often requires us to reference the contents of working memory, the information available for ongoing cognitive processing. As such, understanding how recognition decisions are made when based on the contents of working memory is of critical importance. In this work we examine whether recognition decisions based on the contents of visual working memory follow a continuous decision process of graded information about the correct choice or a discrete decision process reflecting only knowing and guessing. We find a clear pattern in favor of a continuous latent strength model of visual working memory-based decision making, supporting the notion that visual recognition decision processes are impacted by the degree of matching between the contents of working memory and the choices given. Relation to relevant findings and the implications for human information processing more generally are discussed. Copyright © 2016 Cognitive Science Society, Inc.

  19. 21 CFR 133.180 - Pasteurized process cheese spread with fruits, vegetables, or meats.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 2 2011-04-01 2011-04-01 false Pasteurized process cheese spread with fruits... HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION CHEESES AND RELATED CHEESE PRODUCTS Requirements for Specific Standardized Cheese and Related Products § 133.180 Pasteurized process cheese spread...

  20. 21 CFR 133.174 - Pasteurized process cheese food with fruits, vegetables, or meats.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Pasteurized process cheese food with fruits... HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION CHEESES AND RELATED CHEESE PRODUCTS Requirements for Specific Standardized Cheese and Related Products § 133.174 Pasteurized process cheese food...

  1. 21 CFR 133.174 - Pasteurized process cheese food with fruits, vegetables, or meats.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 2 2011-04-01 2011-04-01 false Pasteurized process cheese food with fruits... HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION CHEESES AND RELATED CHEESE PRODUCTS Requirements for Specific Standardized Cheese and Related Products § 133.174 Pasteurized process cheese food...

  2. 21 CFR 133.180 - Pasteurized process cheese spread with fruits, vegetables, or meats.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Pasteurized process cheese spread with fruits... HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION CHEESES AND RELATED CHEESE PRODUCTS Requirements for Specific Standardized Cheese and Related Products § 133.180 Pasteurized process cheese spread...

  3. 40 CFR 63.11395 - What are the standards and compliance requirements for existing sources?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... routine and long-term maintenance) and continuous monitoring system. (4) A list of operating parameters... polymerization process equipment and monomer recovery process equipment and convey the collected gas stream.... (2) 0.05 lb/hr of AN from the control device for monomer recovery process equipment. (3) If you do...

  4. 40 CFR 63.11395 - What are the standards and compliance requirements for existing sources?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... routine and long-term maintenance) and continuous monitoring system. (4) A list of operating parameters... polymerization process equipment and monomer recovery process equipment and convey the collected gas stream.... (2) 0.05 lb/hr of AN from the control device for monomer recovery process equipment. (3) If you do...

  5. 40 CFR 63.11395 - What are the standards and compliance requirements for existing sources?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... routine and long-term maintenance) and continuous monitoring system. (4) A list of operating parameters... polymerization process equipment and monomer recovery process equipment and convey the collected gas stream.... (2) 0.05 lb/hr of AN from the control device for monomer recovery process equipment. (3) If you do...

  6. Eye-Tracking as a Tool in Process-Oriented Reading Test Validation

    ERIC Educational Resources Information Center

    Solheim, Oddny Judith; Uppstad, Per Henning

    2011-01-01

    The present paper addresses the continuous need for methodological reflection on how to validate inferences made on the basis of test scores. Validation is a process that requires many lines of evidence. In this article we discuss the potential of eye tracking methodology in process-oriented reading test validation. Methodological considerations…

  7. Enhancing Student Learning of Enterprise Integration and Business Process Orientation through an ERP Business Simulation Game

    ERIC Educational Resources Information Center

    Seethamraju, Ravi

    2011-01-01

    The sophistication of the integrated world of work and increased recognition of business processes as critical corporate assets require graduates to develop "process orientation" and an "integrated view" of business. Responding to these dynamic changes in business organizations, business schools are also continuing to modify…

  8. 40 CFR 63.114 - Process vent provisions-monitoring requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... but not limited to a thermocouple, ultra-violet beam sensor, or infrared sensor) capable of... accurately. (1) Where an incinerator is used, a temperature monitoring device equipped with a continuous recorder is required. (i) Where an incinerator other than a catalytic incinerator is used, a temperature...

  9. 40 CFR 63.114 - Process vent provisions-monitoring requirements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... but not limited to a thermocouple, ultra-violet beam sensor, or infrared sensor) capable of... accurately. (1) Where an incinerator is used, a temperature monitoring device equipped with a continuous recorder is required. (i) Where an incinerator other than a catalytic incinerator is used, a temperature...

  10. 40 CFR 63.114 - Process vent provisions-monitoring requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... but not limited to a thermocouple, ultra-violet beam sensor, or infrared sensor) capable of... accurately. (1) Where an incinerator is used, a temperature monitoring device equipped with a continuous recorder is required. (i) Where an incinerator other than a catalytic incinerator is used, a temperature...

  11. 40 CFR Table 35 to Subpart G of... - Control Requirements for Items of Equipment That Meet the Criteria of § 63.149 of Subpart G

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS FOR SOURCE CATEGORIES National Emission Standards for Organic Hazardous Air Pollutants From the Synthetic Organic Chemical Manufacturing Industry for Process Vents, Storage...

  12. Combining the Tasks of Grading Individual Assignments and Assessing Student Outcomes in Project-Based Courses

    ERIC Educational Resources Information Center

    Dahm, Kevin

    2014-01-01

    ABET requires that engineering programs demonstrate continuous assessment and continuous improvement in order to be accredited. Central to the process is establishing and assessing measurable "student outcomes" that reflect whether the goals and objectives of the program are being met. This paper examines effective strategies for…

  13. Is Bigger Better? Customer Base Expansion through Word-of-Mouth Reputation

    ERIC Educational Resources Information Center

    Rob, Rafael; Fishman, Arthur

    2005-01-01

    A model of gradual reputation formation through a process of continuous investment in product quality is developed. We assume that the ability to produce high-quality products requires continuous investment and that as a consequence of informational frictions, such as search costs, information about firms' past performance diffuses only gradually…

  14. Space sensors for global change

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Canavan, G.H.

    1994-02-15

    Satellite measurements should contribute to a fuller understanding of the physical processes behind the radiation budget, exchange processes, and global change. Climate engineering requires global observation for early indications of predicted effects, which puts a premium on affordable, distributed constellations of satellites with effective, affordable sensors. Defense has a requirement for continuous global surveillance for warning of aggression, which could evolve from advanced sensors and satellites in development. Many climate engineering needs match those of defense technologies.

  15. The Process by Which Double Base Propellants with Embedded Continuous Wires are Fabricated by Use of the Screw Extruder,

    DTIC Science & Technology

    1983-03-08

    Engineering Research Center in Xian Xian City, People’s Republic of China received June 9, 1981 Abstract This paper describes a process by which the screw... research , it is not only possible to satisfy a full range of design requirements, but also to produce double base propellant grains with continuous...arranged in a radial configuration by the application of an electrical charge. In recent years3 researches on the embedding of wires in propellant

  16. Nonlinear dynamic range transformation in visual communication channels.

    PubMed

    Alter-Gartenberg, R

    1996-01-01

    The article evaluates nonlinear dynamic range transformation in the context of the end-to-end continuous-input/discrete processing/continuous-display imaging process. Dynamic range transformation is required when we have the following: (i) the wide dynamic range encountered in nature is compressed into the relatively narrow dynamic range of the display, particularly for spatially varying irradiance (e.g., shadow); (ii) coarse quantization is expanded to the wider dynamic range of the display; and (iii) nonlinear tone scale transformation compensates for the correction in the camera amplifier.

  17. 5 CFR 838.421 - Application requirements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... (CONTINUED) COURT ORDERS AFFECTING RETIREMENT BENEFITS Procedures for Processing Court Orders Affecting... application letter must be accompanied by— (1) A certified copy of the court order acceptable for processing... the former spouse's representative that the court order is currently in force and has not been amended...

  18. 5 CFR 838.221 - Application requirements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... (CONTINUED) COURT ORDERS AFFECTING RETIREMENT BENEFITS Procedures for Processing Court Orders Affecting... accompanied by— (1) A certified copy of the court order acceptable for processing that is directed at employee... order is currently in force and has not been amended, superseded, or set aside; (3) Information...

  19. 40 CFR 372.20 - Process for modifying covered chemicals and facilities.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... chemicals and facilities. 372.20 Section 372.20 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SUPERFUND, EMERGENCY PLANNING, AND COMMUNITY RIGHT-TO-KNOW PROGRAMS TOXIC CHEMICAL RELEASE REPORTING: COMMUNITY RIGHT-TO-KNOW Reporting Requirements § 372.20 Process for modifying covered chemicals...

  20. 42 CFR 457.1180 - Program specific review process: Notice.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... SERVICES (CONTINUED) STATE CHILDREN'S HEALTH INSURANCE PROGRAMS (SCHIPs) ALLOTMENTS AND GRANTS TO STATES State Plan Requirements: Applicant and Enrollee Protections § 457.1180 Program specific review process... explanation of applicable rights to review of that determination, the standard and expedited time frames for...

  1. 42 CFR 457.1180 - Program specific review process: Notice.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... SERVICES (CONTINUED) STATE CHILDREN'S HEALTH INSURANCE PROGRAMS (SCHIPs) ALLOTMENTS AND GRANTS TO STATES State Plan Requirements: Applicant and Enrollee Protections § 457.1180 Program specific review process... explanation of applicable rights to review of that determination, the standard and expedited time frames for...

  2. 42 CFR 457.1180 - Program specific review process: Notice.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... SERVICES (CONTINUED) STATE CHILDREN'S HEALTH INSURANCE PROGRAMS (SCHIPs) ALLOTMENTS AND GRANTS TO STATES State Plan Requirements: Applicant and Enrollee Protections § 457.1180 Program specific review process... explanation of applicable rights to review of that determination, the standard and expedited time frames for...

  3. 42 CFR 457.1180 - Program specific review process: Notice.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... SERVICES (CONTINUED) STATE CHILDREN'S HEALTH INSURANCE PROGRAMS (SCHIPs) ALLOTMENTS AND GRANTS TO STATES State Plan Requirements: Applicant and Enrollee Protections § 457.1180 Program specific review process... explanation of applicable rights to review of that determination, the standard and expedited time frames for...

  4. 42 CFR 457.1180 - Program specific review process: Notice.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... SERVICES (CONTINUED) STATE CHILDREN'S HEALTH INSURANCE PROGRAMS (SCHIPs) ALLOTMENTS AND GRANTS TO STATES State Plan Requirements: Applicant and Enrollee Protections § 457.1180 Program specific review process... explanation of applicable rights to review of that determination, the standard and expedited time frames for...

  5. 40 CFR 63.1412 - Continuous process vent applicability assessment procedures and methods.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... engineering principles, measurable process parameters, or physical or chemical laws or properties. Examples of... values, and engineering assessment control applicability assessment requirements are to be determined... by using the engineering assessment procedures in paragraph (k) of this section. (f) Volumetric flow...

  6. 40 CFR 63.1412 - Continuous process vent applicability assessment procedures and methods.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... engineering principles, measurable process parameters, or physical or chemical laws or properties. Examples of... values, and engineering assessment control applicability assessment requirements are to be determined... by using the engineering assessment procedures in paragraph (k) of this section. (f) Volumetric flow...

  7. 40 CFR 63.1412 - Continuous process vent applicability assessment procedures and methods.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... engineering principles, measurable process parameters, or physical or chemical laws or properties. Examples of... values, and engineering assessment control applicability assessment requirements are to be determined... by using the engineering assessment procedures in paragraph (k) of this section. (f) Volumetric flow...

  8. 40 CFR 63.1412 - Continuous process vent applicability assessment procedures and methods.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... engineering principles, measurable process parameters, or physical or chemical laws or properties. Examples of... values, and engineering assessment control applicability assessment requirements are to be determined... by using the engineering assessment procedures in paragraph (k) of this section. (f) Volumetric flow...

  9. 40 CFR 63.1412 - Continuous process vent applicability assessment procedures and methods.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... engineering principles, measurable process parameters, or physical or chemical laws or properties. Examples of... values, and engineering assessment control applicability assessment requirements are to be determined... by using the engineering assessment procedures in paragraph (k) of this section. (f) Volumetric flow...

  10. Software process assessments

    NASA Technical Reports Server (NTRS)

    Miller, Sharon E.; Tucker, George T.; Verducci, Anthony J., Jr.

    1992-01-01

    Software process assessments (SPA's) are part of an ongoing program of continuous quality improvements in AT&T. Their use was found to be very beneficial by software development organizations in identifying the issues facing the organization and the actions required to increase both quality and productivity in the organization.

  11. 7 CFR 1780.39 - Application processing.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... shall be payable jointly to the borrower and the United States of America. (5) Applicants must provide a... AGRICULTURE (CONTINUED) WATER AND WASTE LOANS AND GRANTS Loan and Grant Application Processing § 1780.39... documentation requirements, preparation of cost and income estimates, development of proposals for organization...

  12. 7 CFR 1780.39 - Application processing.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... shall be payable jointly to the borrower and the United States of America. (5) Applicants must provide a... AGRICULTURE (CONTINUED) WATER AND WASTE LOANS AND GRANTS Loan and Grant Application Processing § 1780.39... documentation requirements, preparation of cost and income estimates, development of proposals for organization...

  13. 7 CFR 1780.39 - Application processing.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... shall be payable jointly to the borrower and the United States of America. (5) Applicants must provide a... AGRICULTURE (CONTINUED) WATER AND WASTE LOANS AND GRANTS Loan and Grant Application Processing § 1780.39... documentation requirements, preparation of cost and income estimates, development of proposals for organization...

  14. 7 CFR 1780.39 - Application processing.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... shall be payable jointly to the borrower and the United States of America. (5) Applicants must provide a... AGRICULTURE (CONTINUED) WATER AND WASTE LOANS AND GRANTS Loan and Grant Application Processing § 1780.39... documentation requirements, preparation of cost and income estimates, development of proposals for organization...

  15. Efficient Transition Probability Computation for Continuous-Time Branching Processes via Compressed Sensing.

    PubMed

    Xu, Jason; Minin, Vladimir N

    2015-07-01

    Branching processes are a class of continuous-time Markov chains (CTMCs) with ubiquitous applications. A general difficulty in statistical inference under partially observed CTMC models arises in computing transition probabilities when the discrete state space is large or uncountable. Classical methods such as matrix exponentiation are infeasible for large or countably infinite state spaces, and sampling-based alternatives are computationally intensive, requiring integration over all possible hidden events. Recent work has successfully applied generating function techniques to computing transition probabilities for linear multi-type branching processes. While these techniques often require significantly fewer computations than matrix exponentiation, they also become prohibitive in applications with large populations. We propose a compressed sensing framework that significantly accelerates the generating function method, decreasing computational cost up to a logarithmic factor by only assuming the probability mass of transitions is sparse. We demonstrate accurate and efficient transition probability computations in branching process models for blood cell formation and evolution of self-replicating transposable elements in bacterial genomes.

  16. Efficient Transition Probability Computation for Continuous-Time Branching Processes via Compressed Sensing

    PubMed Central

    Xu, Jason; Minin, Vladimir N.

    2016-01-01

    Branching processes are a class of continuous-time Markov chains (CTMCs) with ubiquitous applications. A general difficulty in statistical inference under partially observed CTMC models arises in computing transition probabilities when the discrete state space is large or uncountable. Classical methods such as matrix exponentiation are infeasible for large or countably infinite state spaces, and sampling-based alternatives are computationally intensive, requiring integration over all possible hidden events. Recent work has successfully applied generating function techniques to computing transition probabilities for linear multi-type branching processes. While these techniques often require significantly fewer computations than matrix exponentiation, they also become prohibitive in applications with large populations. We propose a compressed sensing framework that significantly accelerates the generating function method, decreasing computational cost up to a logarithmic factor by only assuming the probability mass of transitions is sparse. We demonstrate accurate and efficient transition probability computations in branching process models for blood cell formation and evolution of self-replicating transposable elements in bacterial genomes. PMID:26949377

  17. 29 CFR 825.500 - Recordkeeping requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Recordkeeping requirements. 825.500 Section 825.500 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR OTHER LAWS THE FAMILY... maintained and preserved on microfilm or other basic source document of an automated data processing memory...

  18. 5 CFR 838.1121 - Procedures and requirements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... REGULATIONS (CONTINUED) COURT ORDERS AFFECTING RETIREMENT BENEFITS Court Orders Under the Child Abuse... requirements applicable to legal process under part 581 of this chapter apply to OPM's administration of child... 581 of this chapter that appears valid on its face. (2)(i) After OPM has determined that a child abuse...

  19. 40 CFR 98.164 - Monitoring and QA/QC requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Hydrogen Production § 98.164 Monitoring and QA/QC requirements. The GHG emissions data for hydrogen production process units must be quality-assured as specified in..., Hydrogen, and Nitrogen in Petroleum Products and Lubricants (incorporated by reference, see § 98.7). (xi...

  20. 40 CFR 63.114 - Process vent provisions-monitoring requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ..., temperature monitoring devices shall be installed in the gas stream immediately before and after the catalyst... but not limited to a thermocouple, ultra-violet beam sensor, or infrared sensor) capable of... monitoring device in the firebox equipped with a continuous recorder. This requirement does not apply to gas...

  1. 40 CFR 63.114 - Process vent provisions-monitoring requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ..., temperature monitoring devices shall be installed in the gas stream immediately before and after the catalyst... but not limited to a thermocouple, ultra-violet beam sensor, or infrared sensor) capable of... monitoring device in the firebox equipped with a continuous recorder. This requirement does not apply to gas...

  2. 50 CFR 20.82 - Records required.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 50 Wildlife and Fisheries 9 2014-10-01 2014-10-01 false Records required. 20.82 Section 20.82 Wildlife and Fisheries UNITED STATES FISH AND WILDLIFE SERVICE, DEPARTMENT OF THE INTERIOR (CONTINUED... clubs which do not fully process migratory birds by removal of both the head and wings. [41 FR 38510...

  3. 50 CFR 20.82 - Records required.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 50 Wildlife and Fisheries 9 2012-10-01 2012-10-01 false Records required. 20.82 Section 20.82 Wildlife and Fisheries UNITED STATES FISH AND WILDLIFE SERVICE, DEPARTMENT OF THE INTERIOR (CONTINUED... clubs which do not fully process migratory birds by removal of both the head and wings. [41 FR 38510...

  4. 50 CFR 20.82 - Records required.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 50 Wildlife and Fisheries 9 2013-10-01 2013-10-01 false Records required. 20.82 Section 20.82 Wildlife and Fisheries UNITED STATES FISH AND WILDLIFE SERVICE, DEPARTMENT OF THE INTERIOR (CONTINUED... clubs which do not fully process migratory birds by removal of both the head and wings. [41 FR 38510...

  5. Flow Asymmetric Propargylation: Development of Continuous Processes for the Preparation of a Chiral β-Amino Alcohol.

    PubMed

    Li, Hui; Sheeran, Jillian W; Clausen, Andrew M; Fang, Yuan-Qing; Bio, Matthew M; Bader, Scott

    2017-08-01

    The development of a flow chemistry process for asymmetric propargylation using allene gas as a reagent is reported. The connected continuous process of allene dissolution, lithiation, Li-Zn transmetallation, and asymmetric propargylation provides homopropargyl β-amino alcohol 1 with high regio- and diastereoselectivity in high yield. This flow process enables practical use of an unstable allenyllithium intermediate. The process uses the commercially available and recyclable (1S,2R)-N-pyrrolidinyl norephedrine as a ligand to promote the highly diastereoselective (32:1) propargylation. Judicious selection of mixers based on the chemistry requirement and real-time monitoring of the process using process analytical technology (PAT) enabled stable and scalable flow chemistry runs. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  6. 21 CFR 133.173 - Pasteurized process cheese food.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 2 2014-04-01 2014-04-01 false Pasteurized process cheese food. 133.173 Section 133.173 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION CHEESES AND RELATED CHEESE PRODUCTS Requirements for Specific...

  7. 21 CFR 133.173 - Pasteurized process cheese food.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 2 2012-04-01 2012-04-01 false Pasteurized process cheese food. 133.173 Section 133.173 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION CHEESES AND RELATED CHEESE PRODUCTS Requirements for Specific...

  8. 21 CFR 133.173 - Pasteurized process cheese food.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 2 2013-04-01 2013-04-01 false Pasteurized process cheese food. 133.173 Section 133.173 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION CHEESES AND RELATED CHEESE PRODUCTS Requirements for Specific...

  9. 40 CFR 63.11561 - What are my standards and management practices?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... CATEGORIES (CONTINUED) National Emission Standards for Hazardous Air Pollutants for Area Sources: Asphalt Processing and Asphalt Roofing Manufacturing Standards and Compliance Requirements § 63.11561 What are my standards and management practices? (a) For asphalt processing operations, you must meet the emission limits...

  10. 40 CFR 63.11561 - What are my standards and management practices?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... CATEGORIES (CONTINUED) National Emission Standards for Hazardous Air Pollutants for Area Sources: Asphalt Processing and Asphalt Roofing Manufacturing Standards and Compliance Requirements § 63.11561 What are my standards and management practices? (a) For asphalt processing operations, you must meet the emission limits...

  11. 40 CFR 63.11561 - What are my standards and management practices?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... CATEGORIES (CONTINUED) National Emission Standards for Hazardous Air Pollutants for Area Sources: Asphalt Processing and Asphalt Roofing Manufacturing Standards and Compliance Requirements § 63.11561 What are my standards and management practices? (a) For asphalt processing operations, you must meet the emission limits...

  12. 40 CFR 63.11561 - What are my standards and management practices?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... CATEGORIES (CONTINUED) National Emission Standards for Hazardous Air Pollutants for Area Sources: Asphalt Processing and Asphalt Roofing Manufacturing Standards and Compliance Requirements § 63.11561 What are my standards and management practices? (a) For asphalt processing operations, you must meet the emission limits...

  13. PF-WFS Shell Inspection Update December 2016

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Vigil, Anthony Eugene; Ledoux, Reina Rebecca; Gonzales, Antonio R.

    Since the last project update in FY16:Q2, PF-WFS personnel have advanced in understanding of shell inspection on Coordinate Measuring Machines {CMM} and refined the PF-WFS process to the point it was decided to convert shell inspection from the Sheffield #1 gage to Lietz CM Ms. As a part of introspection on the quality of this process many sets of data have been reviewed and analyzed. This analysis included Sheffield to CMM comparisons, CMM inspection repeatability, fixturing differences, quality check development, probing approach changes. This update report will touch on these improvements that have built the confidence in this process tomore » mainstream it inspecting shells. In addition to the CMM programming advancements, the continuation in refinement of input and outputs for the CMM program has created an archiving scheme, input spline files, an output metafile, and inspection report package. This project will continue to mature. Part designs may require program modifications to accommodate "new to this process" part designs. Technology limitations tied to security and performance are requiring possible changes to computer configurations to support an automated process.« less

  14. Experimental and Numerical Simulations of Phase Transformations Occurring During Continuous Annealing of DP Steel Strips

    NASA Astrophysics Data System (ADS)

    Wrożyna, Andrzej; Pernach, Monika; Kuziak, Roman; Pietrzyk, Maciej

    2016-04-01

    Due to their exceptional strength properties combined with good workability the Advanced High-Strength Steels (AHSS) are commonly used in automotive industry. Manufacturing of these steels is a complex process which requires precise control of technological parameters during thermo-mechanical treatment. Design of these processes can be significantly improved by the numerical models of phase transformations. Evaluation of predictive capabilities of models, as far as their applicability in simulation of thermal cycles thermal cycles for AHSS is considered, was the objective of the paper. Two models were considered. The former was upgrade of the JMAK equation while the latter was an upgrade of the Leblond model. The models can be applied to any AHSS though the examples quoted in the paper refer to the Dual Phase (DP) steel. Three series of experimental simulations were performed. The first included various thermal cycles going beyond limitations of the continuous annealing lines. The objective was to validate models behavior in more complex cooling conditions. The second set of tests included experimental simulations of the thermal cycle characteristic for the continuous annealing lines. Capability of the models to describe properly phase transformations in this process was evaluated. The third set included data from the industrial continuous annealing line. Validation and verification of models confirmed their good predictive capabilities. Since it does not require application of the additivity rule, the upgrade of the Leblond model was selected as the better one for simulation of industrial processes in AHSS production.

  15. Early Intervention to Support the Academic Recovery of First-Year Students at Risk of Non-Continuation

    ERIC Educational Resources Information Center

    Lizzio, Alf; Wilson, Keithia

    2013-01-01

    The widening participation agenda and related concerns about student retention require a more systematic focus on supporting student success. This paper describes a process designed with the dual goals of supporting the short-term academic recovery of students at risk of non-continuation due to early difficulties with assessment and developing…

  16. Translating Head Motion into Attention - Towards Processing of Student's Body-Language

    ERIC Educational Resources Information Center

    Raca, Mirko; Kidzinski, Lukasz; Dillenbourg, Pierre

    2015-01-01

    Evidence has shown that student's attention is a crucial factor for engagement and learning gain. Although it can be accurately assessed ad-hoc by an experienced teacher, continuous contact with all students in a large class is difficult to maintain and requires training for novice practitioners. We continue our previous work on investigating…

  17. Multimembrane Bioreactor

    NASA Technical Reports Server (NTRS)

    Cho, Toohyon; Shuler, Michael L.

    1989-01-01

    Set of hydrophilic and hydrophobic membranes in bioreactor allows product of reaction to be separated, while nutrients fed to reacting cells and byproducts removed from them. Separation process requires no externally supplied energy; free energy of reaction sufficient. Membranes greatly increase productivity of metabolizing cells by continuously removing product and byproducts, which might otherwise inhibit reaction, and by continuously adding oxygen and organic nutrients.

  18. 40 CFR 63.7985 - Am I subject to the requirements in this subpart?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS FOR SOURCE...)(1) through (4) of this section. (1) Are located at or are part of a major source of hazardous air... as defined in § 63.8105. (3) Process, use, or produce HAP. (4) Are not part of an affected source...

  19. 40 CFR 63.7985 - Am I subject to the requirements in this subpart?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS FOR SOURCE...)(1) through (4) of this section. (1) Are located at or are part of a major source of hazardous air... as defined in § 63.8105. (3) Process, use, or produce HAP. (4) Are not part of an affected source...

  20. Cleaning conveyor belts in the chicken-cutting area of a poultry processing plant with 45°c water.

    PubMed

    Soares, V M; Pereira, J G; Zanette, C M; Nero, L A; Pinto, J P A N; Barcellos, V C; Bersot, L S

    2014-03-01

    Conveyor belts are widely used in food handling areas, especially in poultry processing plants. Because they are in direct contact with food and it is a requirement of the Brazilian health authority, conveyor belts are required to be continuously cleaned with hot water under pressure. The use of water in this procedure has been questioned based on the hypothesis that water may further disseminate microorganisms but not effectively reduce the organic material on the surface. Moreover, reducing the use of water in processing may contribute to a reduction in costs and emission of effluents. However, no consistent evidence in support of removing water during conveyor belt cleaning has been reported. Therefore, the objective of the present study was to compare the bacterial counts on conveyor belts that were or were not continuously cleaned with hot water under pressure. Superficial samples from conveyor belts (cleaned or not cleaned) were collected at three different times during operation (T1, after the preoperational cleaning [5 a.m.]; T2, after the first work shift [4 p.m.]; and T3, after the second work shift [1:30 a.m.]) in a poultry meat processing facility, and the samples were subjected to mesophilic and enterobacterial counts. For Enterobacteriaceae, no significant differences were observed between the conveyor belts, independent of the time of sampling or the cleaning process. No significant differences were observed between the counts of mesophilic bacteria at the distinct times of sampling on the conveyor belt that had not been subjected to continuous cleaning with water at 45°C. When comparing similar periods of sampling, no significant differences were observed between the mesophilic counts obtained from the conveyor belts that were or were not subjected to continuous cleaning with water at 45°C. Continuous cleaning with water did not significantly reduce microorganism counts, suggesting the possibility of discarding this procedure in chicken processing.

  1. Structure and Randomness of Continuous-Time, Discrete-Event Processes

    NASA Astrophysics Data System (ADS)

    Marzen, Sarah E.; Crutchfield, James P.

    2017-10-01

    Loosely speaking, the Shannon entropy rate is used to gauge a stochastic process' intrinsic randomness; the statistical complexity gives the cost of predicting the process. We calculate, for the first time, the entropy rate and statistical complexity of stochastic processes generated by finite unifilar hidden semi-Markov models—memoryful, state-dependent versions of renewal processes. Calculating these quantities requires introducing novel mathematical objects (ɛ -machines of hidden semi-Markov processes) and new information-theoretic methods to stochastic processes.

  2. Airline business continuity and IT disaster recovery sites.

    PubMed

    Haji, Jassim

    2016-01-01

    Business continuity is defined as the capability of the organisation to continue delivery of products or services at acceptable predefined levels following a disruptive incident. Business continuity is fast evolving to become a critical and strategic decision for any organisation. Transportation in general, and airlines in particular, is a unique sector with a specialised set of requirements, challenges and opportunities. Business continuity in the airline sector is a concept that is generally overlooked by the airline managements. This paper reviews different risks related to airline processes and will also propose solutions to these risks based on experiences and good industry practices.

  3. Process Requirements for Achieving Full-Flow Disinfection of Recirculating Water Using Ozonation and UV Irradiation

    USDA-ARS?s Scientific Manuscript database

    A continuous water disinfection process can be used to prevent the introduction and accumulation of obligate and opportunistic fish pathogens in recirculating aquaculture systems (RAS), especially during a disease outbreak when the causative agent would otherwise proliferate within the system. To p...

  4. 47 CFR 52.36 - Standard data fields for simple port order processing.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 3 2012-10-01 2012-10-01 false Standard data fields for simple port order... CARRIER SERVICES (CONTINUED) NUMBERING Number Portability § 52.36 Standard data fields for simple port order processing. (a) A telecommunications carrier may require only the data described in paragraphs (b...

  5. 40 CFR 63.1013 - Sampling connection systems standards.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... (CONTINUED) National Emission Standards for Equipment Leaks-Control Level 1 § 63.1013 Sampling connection... container are not required to be collected or captured. (c) Equipment design and operation. Each closed... process fluid to a process; or (3) Be designed and operated to capture and transport all the purged...

  6. Process test plan, phase II: waste retrieval sluicing system emissions collection

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    POWERS, R.L.

    1999-06-01

    This Process Test Plan is prepared to continue from HNF-3733 which was Phase I of the test. Supplemental operational controls and sampling requirements are defined to safely obtain gas samples from the 296-C-006 ventilation system stack during active operation of the sluicing equipment.

  7. 27 CFR 41.262 - Reports.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... TREASURY (CONTINUED) TOBACCO IMPORTATION OF TOBACCO PRODUCTS, CIGARETTE PAPERS AND TUBES, AND PROCESSED... is not required to report such shipment or transfer on TTB F 5250.2. (e) Concluding report. When a...

  8. Comparison of property between two Viking Seismic tapes

    NASA Astrophysics Data System (ADS)

    Yamamoto, Y.; Yamada, R.

    2016-12-01

    Tthe restoration work of the seismometer data onboard Viking Lander 2 is still continuing. Originally, the data were processed and archived both in MIT and UTIG separately, and each data is accessible via the Internet today. Their file formats to store the data are different, but both of them are currently readable due to the continuous investigation. However, there is some inconsistency between their data although most of their data are highly consistent. To understand the differences, the knowledge of archiving and off-line processing of spacecraft is required because these differences are caused by the off-line processing.The data processing of spacecraft often requires merge and sort processing of raw data. The merge processing is normally performed to eliminate duplicated data, and the sort processing is performed to fix data order. UTIG did not seem to perform these merge and sort processing. Therefore, the UTIG processed data remain duplication. The MIT processed data did these merge and sort processing, but the raw data sometimes include wrong time tags, and it cannot be fixed strictly after sort processing. Also, the MIT processed data has enough documents to understand metadata, while UTIG data has a brief instruction. Therefore, both of MIT and UTIG data are treated complementary. A better data set can be established using both of them. In this presentation, we would show the method to build a better data set of Viking Lander 2 seismic data.

  9. 40 CFR 63.1366 - Monitoring and inspection requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Production § 63.1366 Monitoring and inspection requirements. (a) To provide evidence of continued compliance... shall be divided by the production rate, per process, for 12-month periods at the frequency specified in... hydrocarbon in air); and (B) Mixtures of methane in air at a concentration less than 10,000 parts per million...

  10. 40 CFR 63.1366 - Monitoring and inspection requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Production § 63.1366 Monitoring and inspection requirements. (a) To provide evidence of continued compliance... of both total HAP and total VOC shall be divided by the production rate, per process, for 12-month... parts per million hydrocarbon in air); and (B) Mixtures of methane in air at a concentration less than...

  11. 17 CFR 240.17Ad-19 - Requirements for cancellation, processing, storage, transportation, and destruction or other...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Requirements for cancellation....17Ad-19 Section 240.17Ad-19 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) GENERAL RULES AND REGULATIONS, SECURITIES EXCHANGE ACT OF 1934 Rules and Regulations Under the...

  12. 29 CFR 780.129 - Required relationship of practices to farming operations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Required relationship of practices to farming operations. 780.129 Section 780.129 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR STATEMENTS OF GENERAL POLICY OR INTERPRETATION NOT DIRECTLY RELATED TO REGULATIONS EXEMPTIONS APPLICABLE TO AGRICULTURE, PROCESSING OF...

  13. Higher Romanian Education Post-Bologna: Required Changes, Instruments and Ethical Issues

    ERIC Educational Resources Information Center

    Petrisor, Alexandru-Ionut

    2011-01-01

    In 1999 Romania became part of the Bologna process, focused on the European Credit Transfer and Accumulation System, design to increase the compatibility of European universities, ensuring the mobility of students and professors in the context of re-orienting education to the formation of competences continuously adapted to market requirements.…

  14. 21 CFR 701.9 - Exemptions from labeling requirements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... (CONTINUED) COSMETICS COSMETIC LABELING General Provisions § 701.9 Exemptions from labeling requirements. (a) Except as provided by paragraphs (b) and (c) of this section, a shipment or other delivery of a cosmetic... establishment where such cosmetic is to be processed, labeled, or repacked; or (2) In case such person is not...

  15. 21 CFR 701.9 - Exemptions from labeling requirements.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... (CONTINUED) COSMETICS COSMETIC LABELING General Provisions § 701.9 Exemptions from labeling requirements. (a) Except as provided by paragraphs (b) and (c) of this section, a shipment or other delivery of a cosmetic... establishment where such cosmetic is to be processed, labeled, or repacked; or (2) In case such person is not...

  16. 21 CFR 701.9 - Exemptions from labeling requirements.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... (CONTINUED) COSMETICS COSMETIC LABELING General Provisions § 701.9 Exemptions from labeling requirements. (a) Except as provided by paragraphs (b) and (c) of this section, a shipment or other delivery of a cosmetic... establishment where such cosmetic is to be processed, labeled, or repacked; or (2) In case such person is not...

  17. 21 CFR 701.9 - Exemptions from labeling requirements.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... (CONTINUED) COSMETICS COSMETIC LABELING General Provisions § 701.9 Exemptions from labeling requirements. (a) Except as provided by paragraphs (b) and (c) of this section, a shipment or other delivery of a cosmetic... establishment where such cosmetic is to be processed, labeled, or repacked; or (2) In case such person is not...

  18. PSP, TSP, XP, CMMI...Eating the Alphabet Soup!

    DTIC Science & Technology

    2011-05-19

    Operations and Reports, 1215 Jefferson Davis Highway, Suite 1204, Arlington VA 22202-4302. Respondents should be aware that notwithstanding any other...4 Q tit t Continuous process improvement Organizational Performance Management Causal Analysis and Resolution Level Focus Process Areas Requirements...Project Management process standardization Risk management Decision Analysis and Resolution Product Integration 2 M d R i t t anage Basic Project

  19. Using PAT to accelerate the transition to continuous API manufacturing.

    PubMed

    Gouveia, Francisca F; Rahbek, Jesper P; Mortensen, Asmus R; Pedersen, Mette T; Felizardo, Pedro M; Bro, Rasmus; Mealy, Michael J

    2017-01-01

    Significant improvements can be realized by converting conventional batch processes into continuous ones. The main drivers include reduction of cost and waste, increased safety, and simpler scale-up and tech transfer activities. Re-designing the process layout offers the opportunity to incorporate a set of process analytical technologies (PAT) embraced in the Quality-by-Design (QbD) framework. These tools are used for process state estimation, providing enhanced understanding of the underlying variability in the process impacting quality and yield. This work describes a road map for identifying the best technology to speed-up the development of continuous processes while providing the basis for developing analytical methods for monitoring and controlling the continuous full-scale reaction. The suitability of in-line Raman, FT-infrared (FT-IR), and near-infrared (NIR) spectroscopy for real-time process monitoring was investigated in the production of 1-bromo-2-iodobenzene. The synthesis consists of three consecutive reaction steps including the formation of an unstable diazonium salt intermediate, which is critical to secure high yield and avoid formation of by-products. All spectroscopic methods were able to capture critical information related to the accumulation of the intermediate with very similar accuracy. NIR spectroscopy proved to be satisfactory in terms of performance, ease of installation, full-scale transferability, and stability to very adverse process conditions. As such, in-line NIR was selected to monitor the continuous full-scale production. The quantitative method was developed against theoretical concentration values of the intermediate since representative sampling for off-line reference analysis cannot be achieved. The rapid and reliable analytical system allowed the following: speeding up the design of the continuous process and a better understanding of the manufacturing requirements to ensure optimal yield and avoid unreacted raw materials and by-products in the continuous reactor effluent. Graphical Abstract Using PAT to accelerate the transition to continuous API manufacturing.

  20. In-line Raman spectroscopic monitoring and feedback control of a continuous twin-screw pharmaceutical powder blending and tableting process.

    PubMed

    Nagy, Brigitta; Farkas, Attila; Gyürkés, Martin; Komaromy-Hiller, Szofia; Démuth, Balázs; Szabó, Bence; Nusser, Dávid; Borbás, Enikő; Marosi, György; Nagy, Zsombor Kristóf

    2017-09-15

    The integration of Process Analytical Technology (PAT) initiative into the continuous production of pharmaceuticals is indispensable for reliable production. The present paper reports the implementation of in-line Raman spectroscopy in a continuous blending and tableting process of a three-component model pharmaceutical system, containing caffeine as model active pharmaceutical ingredient (API), glucose as model excipient and magnesium stearate as lubricant. The real-time analysis of API content, blend homogeneity, and tablet content uniformity was performed using a Partial Least Squares (PLS) quantitative method. The in-line Raman spectroscopic monitoring showed that the continuous blender was capable of producing blends with high homogeneity, and technological malfunctions can be detected by the proposed PAT method. The Raman spectroscopy-based feedback control of the API feeder was also established, creating a 'Process Analytically Controlled Technology' (PACT), which guarantees the required API content in the produced blend. This is, to the best of the authors' knowledge, the first ever application of Raman-spectroscopy in continuous blending and the first Raman-based feedback control in the formulation technology of solid pharmaceuticals. Copyright © 2017 Elsevier B.V. All rights reserved.

  1. Continuous direct tablet compression: effects of impeller rotation rate, total feed rate and drug content on the tablet properties and drug release.

    PubMed

    Järvinen, Maiju A; Paaso, Janne; Paavola, Marko; Leiviskä, Kauko; Juuti, Mikko; Muzzio, Fernando; Järvinen, Kristiina

    2013-11-01

    Continuous processing is becoming popular in the pharmaceutical industry for its cost and quality advantages. This study evaluated the mechanical properties, uniformity of dosage units and drug release from the tablets prepared by continuous direct compression process. The tablet formulations consisted of acetaminophen (3-30% (w/w)) pre-blended with 0.25% (w/w) colloidal silicon dioxide, microcrystalline cellulose (69-96% (w/w)) and magnesium stearate (1% (w/w)). The continuous tableting line consisted of three loss-in-weight feeders and a convective continuous mixer and a rotary tablet press. The process continued for 8 min and steady state was reached within 5 min. The effects of acetaminophen content, impeller rotation rate (39-254 rpm) and total feed rate (15 and 20 kg/h) on tablet properties were examined. All the tablets complied with the friability requirements of European Pharmacopoeia and rapidly released acetaminophen. However, the relative standard deviation of acetaminophen content (10% (w/w)) increased with an increase in impeller rotation rate at a constant total feed rate (20 kg/h). A compression force of 12 kN tended to result in greater tablet hardness and subsequently a slower initial acetaminophen release from tablets when compared with those made with the compression force of about 8 kN. In conclusion, tablets could be successfully prepared by a continuous direct compression process and process conditions affected to some extent tablet properties.

  2. Facilitating NASA's Use of GEIA-STD-0005-1, Performance Standard for Aerospace and High Performance Electronic Systems Containing Lead-Free Solder

    NASA Technical Reports Server (NTRS)

    Plante, Jeannete

    2010-01-01

    GEIA-STD-0005-1 defines the objectives of, and requirements for, documenting processes that assure customers and regulatory agencies that AHP electronic systems containing lead-free solder, piece parts, and boards will satisfy the applicable requirements for performance, reliability, airworthiness, safety, and certify-ability throughout the specified life of performance. It communicates requirements for a Lead-Free Control Plan (LFCP) to assist suppliers in the development of their own Plans. The Plan documents the Plan Owner's (supplier's) processes, that assure their customer, and all other stakeholders that the Plan owner's products will continue to meet their requirements. The presentation reviews quality assurance requirements traceability and LFCP template instructions.

  3. Simulation Modeling of Software Development Processes

    NASA Technical Reports Server (NTRS)

    Calavaro, G. F.; Basili, V. R.; Iazeolla, G.

    1996-01-01

    A simulation modeling approach is proposed for the prediction of software process productivity indices, such as cost and time-to-market, and the sensitivity analysis of such indices to changes in the organization parameters and user requirements. The approach uses a timed Petri Net and Object Oriented top-down model specification. Results demonstrate the model representativeness, and its usefulness in verifying process conformance to expectations, and in performing continuous process improvement and optimization.

  4. Six Lessons We Learned Applying Six Sigma

    NASA Technical Reports Server (NTRS)

    Carroll, Napoleon; Casleton, Christa H.

    2005-01-01

    As Chief Financial Officer of Kennedy Space Center (KSC), I'm not only responsible for financial planning and accounting but also for building strong partnerships with the CFO customers, who include Space Shuttle and International Space Station operations as well all who manage the KSC Spaceport. My never ending goal is to design, manage and continuously improve our core business processes so that they deliver world class products and services to the CFO's customers. I became interested in Six Sigma as Christa Casleton (KSC's first Six Sigma Black belt) applied Six Sigma tools and methods to our Plan and Account for Travel Costs Process. Her analysis was fresh, innovative and thorough but, even more impressive, was her approach to ensure ongoing, continuous process improvement. Encouraged by the results, I launched two more process improvement initiatives aimed at applying Six Sigma principles to CFO processes that not only touch most of my employees but also have direct customer impact. As many of you know, Six Sigma is a measurement scale that compares the output of a process with customer requirements. That's straight forward, but demands that you not only understand your processes but also know your products and the critical customer requirements. The objective is to isolate and eliminate the causes of process variation so that the customer sees consistently high quality.

  5. 40 CFR 63.1333 - Additional requirements for performance testing.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... paragraphs (b)(1) and (b)(2) of this section. ER19JN00.041 Where: ERMBS = Emission rate of organic HAP or TOC from continuous process vents, kg/Mg product. Ei = Emission rate of organic HAP or TOC from continuous... hours in a year for control device j. Ei=Mass rate of TOC or total organic HAP at the inlet of control...

  6. 40 CFR 63.2480 - What requirements must I meet for equipment leaks?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... connectors at your affected source. (5) For pumps in light liquid service in an MCPU that has no continuous... connectors in gas/vapor and light liquid service at an existing source, you may elect to comply with the... in light liquid service in an MCPU that has no continuous process vents and is part of an existing...

  7. 40 CFR 63.2480 - What requirements must I meet for equipment leaks?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... connectors at your affected source. (5) For pumps in light liquid service in an MCPU that has no continuous... connectors in gas/vapor and light liquid service at an existing source, you may elect to comply with the... in light liquid service in an MCPU that has no continuous process vents and is part of an existing...

  8. 40 CFR 63.2480 - What requirements must I meet for equipment leaks?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... connectors at your affected source. (5) For pumps in light liquid service in an MCPU that has no continuous... connectors in gas/vapor and light liquid service at an existing source, you may elect to comply with the... in light liquid service in an MCPU that has no continuous process vents and is part of an existing...

  9. NASA Case Sensitive Review and Audit Approach

    NASA Astrophysics Data System (ADS)

    Lee, Arthur R.; Bacus, Thomas H.; Bowersox, Alexandra M.; Newman, J. Steven

    2005-12-01

    As an Agency involved in high-risk endeavors NASA continually reassesses its commitment to engineering excellence and compliance to requirements. As a component of NASA's continual process improvement, the Office of Safety and Mission Assurance (OSMA) established the Review and Assessment Division (RAD) [1] to conduct independent audits to verify compliance with Agency requirements that impact safe and reliable operations. In implementing its responsibilities, RAD benchmarked various approaches for conducting audits, focusing on organizations that, like NASA, operate in high-risk environments - where seemingly inconsequential departures from safety, reliability, and quality requirements can have catastrophic impact to the public, NASA personnel, high-value equipment, and the environment. The approach used by the U.S. Navy Submarine Program [2] was considered the most fruitful framework for the invigorated OSMA audit processes. Additionally, the results of benchmarking activity revealed that not all audits are conducted using just one approach or even with the same objectives. This led to the concept of discrete, unique "audit cases."

  10. Variational objective analysis for cyclone studies

    NASA Technical Reports Server (NTRS)

    Achtemeier, Gary L.

    1989-01-01

    Significant accomplishments during 1987 to 1988 are summarized with regard to each of the major project components. Model 1 requires satisfaction of two nonlinear horizontal momentum equations, the integrated continuity equation, and the hydrostatic equation. Model 2 requires satisfaction of model 1 plus the thermodynamic equation for a dry atmosphere. Model 3 requires satisfaction of model 2 plus the radiative transfer equation. Model 4 requires satisfaction of model 3 plus a moisture conservation equation and a parameterization for moist processes.

  11. 40 CFR 63.11565 - What general provisions sections apply to this subpart?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... CATEGORIES (CONTINUED) National Emission Standards for Hazardous Air Pollutants for Area Sources: Asphalt Processing and Asphalt Roofing Manufacturing Other Requirements and Information § 63.11565 What general...

  12. 40 CFR 63.11565 - What general provisions sections apply to this subpart?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... CATEGORIES (CONTINUED) National Emission Standards for Hazardous Air Pollutants for Area Sources: Asphalt Processing and Asphalt Roofing Manufacturing Other Requirements and Information § 63.11565 What general...

  13. 40 CFR 63.11565 - What general provisions sections apply to this subpart?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... CATEGORIES (CONTINUED) National Emission Standards for Hazardous Air Pollutants for Area Sources: Asphalt Processing and Asphalt Roofing Manufacturing Other Requirements and Information § 63.11565 What general...

  14. 40 CFR 63.11565 - What general provisions sections apply to this subpart?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... CATEGORIES (CONTINUED) National Emission Standards for Hazardous Air Pollutants for Area Sources: Asphalt Processing and Asphalt Roofing Manufacturing Other Requirements and Information § 63.11565 What general...

  15. 40 CFR 63.11565 - What general provisions sections apply to this subpart?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... CATEGORIES (CONTINUED) National Emission Standards for Hazardous Air Pollutants for Area Sources: Asphalt Processing and Asphalt Roofing Manufacturing Other Requirements and Information § 63.11565 What general...

  16. 40 CFR 63.1080 - What is the purpose of this subpart?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... (CONTINUED) National Emission Standards for Ethylene Manufacturing Process Units: Heat Exchange Systems and... requirements for controlling emissions of hazardous air pollutants (HAP) from heat exchange systems and waste...

  17. 40 CFR 63.1080 - What is the purpose of this subpart?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... (CONTINUED) National Emission Standards for Ethylene Manufacturing Process Units: Heat Exchange Systems and... requirements for controlling emissions of hazardous air pollutants (HAP) from heat exchange systems and waste...

  18. 40 CFR 63.1080 - What is the purpose of this subpart?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... (CONTINUED) National Emission Standards for Ethylene Manufacturing Process Units: Heat Exchange Systems and... requirements for controlling emissions of hazardous air pollutants (HAP) from heat exchange systems and waste...

  19. 40 CFR 63.1080 - What is the purpose of this subpart?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... (CONTINUED) National Emission Standards for Ethylene Manufacturing Process Units: Heat Exchange Systems and... requirements for controlling emissions of hazardous air pollutants (HAP) from heat exchange systems and waste...

  20. 40 CFR 63.1080 - What is the purpose of this subpart?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... (CONTINUED) National Emission Standards for Ethylene Manufacturing Process Units: Heat Exchange Systems and... requirements for controlling emissions of hazardous air pollutants (HAP) from heat exchange systems and waste...

  1. Feasibility of utilizing bioindicators for testing microbial inactivation in sweetpotato purees processed with a continuous-flow microwave system.

    PubMed

    Brinley, T A; Dock, C N; Truong, V-D; Coronel, P; Kumar, P; Simunovic, J; Sandeep, K P; Cartwright, G D; Swartzel, K R; Jaykus, L-A

    2007-06-01

    Continuous-flow microwave heating has potential in aseptic processing of various food products, including purees from sweetpotatoes and other vegetables. Establishing the feasibility of a new processing technology for achieving commercial sterility requires evaluating microbial inactivation. This study aimed to assess the feasibility of using commercially available plastic pouches of bioindicators containing spores of Geobacillius stearothermophilus ATCC 7953 and Bacillus subtilis ATCC 35021 for evaluating the degree of microbial inactivation achieved in vegetable purees processed in a continuous-flow microwave heating unit. Sweetpotato puree seeded with the bioindicators was subjected to 3 levels of processing based on the fastest particles: undertarget process (F(0) approximately 0.65), target process (F(0) approximately 2.8), and overtarget process (F(0) approximately 10.10). After initial experiments, we found it was necessary to engineer a setup with 2 removable tubes connected to the continuous-flow microwave system to facilitate the injection of indicators into the unit without interrupting the puree flow. Using this approach, 60% of the indicators injected into the system could be recovered postprocess. Spore survival after processing, as evaluated by use of growth indicator dyes and standard plating methods, verified inactivation of the spores in sweetpotato puree. The log reduction results for B. subtilis were equivalent to the predesigned degrees of sterilization (F(0)). This study presents the first report suggesting that bioindicators such as the flexible, food-grade plastic pouches can be used for microbial validation of commercial sterilization in aseptic processing of foods using a continuous-flow microwave system.

  2. Postacute Care in Cancer Rehabilitation.

    PubMed

    Guo, Ying; Fu, Jack B; Guo, Hong; Camp, Jennifer; Shin, Ki Y; Tu, Shi-Ming; Palmer, Lynn J; Yadav, Rajesh

    2017-02-01

    Acute care is usually associated with disease progression, treatments for cancer, and medical comorbidities. Patients with cancer may develop sudden functional deficits that require rehabilitation. Some of these patients benefit from acute rehabilitation, others benefit from subacute rehabilitation. After acute rehabilitation, continuous care for these patients has not been well described. Three studies are presented to demonstrate that cancer rehabilitation is a continuous process. Rehabilitation professionals should know how to detect fall risk, monitor symptoms, and render symptom management. Patients with cancer often require rehabilitation services during their entire disease trajectory. Copyright © 2016 Elsevier Inc. All rights reserved.

  3. Continuous Removal of Coal-Gasification Residue

    NASA Technical Reports Server (NTRS)

    Collins, Earl R., Jr.; Suitor, J.; Dubis, D.

    1986-01-01

    Continuous-flow hopper processes solid residue from coal gasification, converting it from ashes, cinders, and clinkers to particles size of sand granules. Unit does not require repeated depressurization of lockhopper to admit and release materials. Therefore consumes less energy. Because unit has no airlock valves opened and closed repeatedly on hot, abrasive particles, subjected to lesser wear. Coal-gasification residue flows slowly through pressure-letdown device. Material enters and leaves continuously. Cleanout door on each pressure-letdown chamber allows access for maintenance and emergencies.

  4. Design Research with a Focus on Learning Processes: An Overview on Achievements and Challenges

    ERIC Educational Resources Information Center

    Prediger, Susanne; Gravemeijer, Koeno; Confrey, Jere

    2015-01-01

    Design research continues to gain prominence as a significant methodology in the mathematics education research community. This overview summarizes the origins and the current state of design research practices focusing on methodological requirements and processes of theorizing. While recognizing the rich variations in the foci and scale of design…

  5. 40 CFR 62.14470 - When must I comply with this subpart if I plan to continue operation of my HMIWI?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... FOR DESIGNATED FACILITIES AND POLLUTANTS Federal Plan Requirements for Hospital/Medical/Infectious... air pollution control equipment or process changes such that the HMIWI is brought on line, and ensuring that all necessary process changes and air pollution control equipment are operating properly. (3...

  6. 40 CFR 62.14470 - When must I comply with this subpart if I plan to continue operation of my HMIWI?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... FOR DESIGNATED FACILITIES AND POLLUTANTS Federal Plan Requirements for Hospital/Medical/Infectious... air pollution control equipment or process changes such that the HMIWI is brought on line, and ensuring that all necessary process changes and air pollution control equipment are operating properly. (3...

  7. Terminology and biology of fire scars in selected central hardwoods

    Treesearch

    Kevin T. Smith; Elaine Kennedy Sutherland

    2001-01-01

    Dendrochronological analysis of fire scars requires tree survival of fire exposure. Trees survive fire exposure by: (1) avoidance of injury through constitutive protection and (2) induced defense. Induced defenses include (a) compartmentalization processes that resist the spread of injury and infection and (b) closure processes that restore the continuity of the...

  8. 15 CFR 713.2 - Annual declaration requirements for plant sites that produce, process or consume Schedule 2...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... a chemical in any units within the same plant through chemical reaction, including any associated... plant sites that produce, process or consume Schedule 2 chemicals in excess of specified thresholds. 713... (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE CHEMICAL WEAPONS CONVENTION REGULATIONS...

  9. 15 CFR 713.2 - Annual declaration requirements for plant sites that produce, process or consume Schedule 2...

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... a chemical in any units within the same plant through chemical reaction, including any associated... plant sites that produce, process or consume Schedule 2 chemicals in excess of specified thresholds. 713... (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE CHEMICAL WEAPONS CONVENTION REGULATIONS...

  10. 15 CFR 713.2 - Annual declaration requirements for plant sites that produce, process or consume Schedule 2...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... a chemical in any units within the same plant through chemical reaction, including any associated... plant sites that produce, process or consume Schedule 2 chemicals in excess of specified thresholds. 713... (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE CHEMICAL WEAPONS CONVENTION REGULATIONS...

  11. 15 CFR 713.2 - Annual declaration requirements for plant sites that produce, process or consume Schedule 2...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... a chemical in any units within the same plant through chemical reaction, including any associated... plant sites that produce, process or consume Schedule 2 chemicals in excess of specified thresholds. 713... (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE CHEMICAL WEAPONS CONVENTION REGULATIONS...

  12. Assessing Faculty Bias in Rating Embedded Assurance of Learning Assignments

    ERIC Educational Resources Information Center

    Kim, Dong-gook; Helms, Marilyn M.

    2016-01-01

    Assurance of learning (AoL) processes for continuous improvement and accreditation require business schools to assess program goals. Findings from the process can lead to changes in course design or curriculum. Often AoL assignments are embedded into existing courses and assessed at regular intervals. Faculty members may evaluate an assignment in…

  13. Multisite Assessment of Nursing Continuing Education Learning Needs Using an Electronic Tool.

    PubMed

    Winslow, Susan; Jackson, Stephanie; Cook, Lesley; Reed, Joanne Williams; Blakeney, Keshia; Zimbro, Kathie; Parker, Cindy

    2016-02-01

    A continued education needs assessment and associated education plan are required for organizations on the journey for American Nurses Credentialing Center Magnet® designation. Leveraging technology to support the assessment and analysis of continuing education needs was a new venture for a 12-hospital regional health system. The purpose of this performance improvement project was to design and conduct an enhanced process to increase the efficiency and effectiveness of gathering data on nurses' preferences and increase nurse satisfaction with the learner assessment portion of the process. Educators trialed the use of a standardized approach via an electronic survey tool to replace the highly variable processes previously used. Educators were able to view graphical summary of responses by category and setting, which substantially decreased analysis and action planning time for education implementation plans at the system, site, or setting level. Based on these findings, specific continuing education action plans were drafted for each category and classification of nurses. Copyright 2016, SLACK Incorporated.

  14. 40 CFR 63.8696 - What parts of the General Provisions apply to me?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... CATEGORIES (CONTINUED) National Emission Standards for Hazardous Air Pollutants: Asphalt Processing and Asphalt Roofing Manufacturing Other Requirements and Information § 63.8696 What parts of the General...

  15. 40 CFR 63.8696 - What parts of the General Provisions apply to me?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... CATEGORIES (CONTINUED) National Emission Standards for Hazardous Air Pollutants: Asphalt Processing and Asphalt Roofing Manufacturing Other Requirements and Information § 63.8696 What parts of the General...

  16. 40 CFR 63.8696 - What parts of the General Provisions apply to me?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... CATEGORIES (CONTINUED) National Emission Standards for Hazardous Air Pollutants: Asphalt Processing and Asphalt Roofing Manufacturing Other Requirements and Information § 63.8696 What parts of the General...

  17. 40 CFR 63.8696 - What parts of the General Provisions apply to me?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... CATEGORIES (CONTINUED) National Emission Standards for Hazardous Air Pollutants: Asphalt Processing and Asphalt Roofing Manufacturing Other Requirements and Information § 63.8696 What parts of the General...

  18. 40 CFR 63.8696 - What parts of the General Provisions apply to me?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... CATEGORIES (CONTINUED) National Emission Standards for Hazardous Air Pollutants: Asphalt Processing and Asphalt Roofing Manufacturing Other Requirements and Information § 63.8696 What parts of the General...

  19. Control of three different continuous pharmaceutical manufacturing processes: Use of soft sensors.

    PubMed

    Rehrl, Jakob; Karttunen, Anssi-Pekka; Nicolaï, Niels; Hörmann, Theresa; Horn, Martin; Korhonen, Ossi; Nopens, Ingmar; De Beer, Thomas; Khinast, Johannes G

    2018-05-30

    One major advantage of continuous pharmaceutical manufacturing over traditional batch manufacturing is the possibility of enhanced in-process control, reducing out-of-specification and waste material by appropriate discharge strategies. The decision on material discharge can be based on the measurement of active pharmaceutical ingredient (API) concentration at specific locations in the production line via process analytic technology (PAT), e.g. near-infrared (NIR) spectrometers. The implementation of the PAT instruments is associated with monetary investment and the long term operation requires techniques avoiding sensor drifts. Therefore, our paper proposes a soft sensor approach for predicting the API concentration from the feeder data. In addition, this information can be used to detect sensor drift, or serve as a replacement/supplement of specific PAT equipment. The paper presents the experimental determination of the residence time distribution of selected unit operations in three different continuous processing lines (hot melt extrusion, direct compaction, wet granulation). The mathematical models describing the soft sensor are developed and parameterized. Finally, the suggested soft sensor approach is validated on the three mentioned, different continuous processing lines, demonstrating its versatility. Copyright © 2018 Elsevier B.V. All rights reserved.

  20. What is the Final Verification of Engineering Requirements?

    NASA Technical Reports Server (NTRS)

    Poole, Eric

    2010-01-01

    This slide presentation reviews the process of development through the final verification of engineering requirements. The definition of the requirements is driven by basic needs, and should be reviewed by both the supplier and the customer. All involved need to agree upon a formal requirements including changes to the original requirements document. After the requirements have ben developed, the engineering team begins to design the system. The final design is reviewed by other organizations. The final operational system must satisfy the original requirements, though many verifications should be performed during the process. The verification methods that are used are test, inspection, analysis and demonstration. The plan for verification should be created once the system requirements are documented. The plan should include assurances that every requirement is formally verified, that the methods and the responsible organizations are specified, and that the plan is reviewed by all parties. The options of having the engineering team involved in all phases of the development as opposed to having some other organization continue the process once the design has been complete is discussed.

  1. Fiberboards from loblolly pine refiner groundwood: effects of gross wood characteristics and board density

    Treesearch

    Charles W. McMillin

    1968-01-01

    Boards for insulation and and structural uses are being manufactured in increasing quantities. The coarse fiber required for these products can be disk-refined from untreated wood chips. Since such fiber is produced in essentially one mechanical operation, continuous control is required of the raw material as well as the refining process.

  2. Universal Quantum Computing with Arbitrary Continuous-Variable Encoding.

    PubMed

    Lau, Hoi-Kwan; Plenio, Martin B

    2016-09-02

    Implementing a qubit quantum computer in continuous-variable systems conventionally requires the engineering of specific interactions according to the encoding basis states. In this work, we present a unified formalism to conduct universal quantum computation with a fixed set of operations but arbitrary encoding. By storing a qubit in the parity of two or four qumodes, all computing processes can be implemented by basis state preparations, continuous-variable exponential-swap operations, and swap tests. Our formalism inherits the advantages that the quantum information is decoupled from collective noise, and logical qubits with different encodings can be brought to interact without decoding. We also propose a possible implementation of the required operations by using interactions that are available in a variety of continuous-variable systems. Our work separates the "hardware" problem of engineering quantum-computing-universal interactions, from the "software" problem of designing encodings for specific purposes. The development of quantum computer architecture could hence be simplified.

  3. Universal Quantum Computing with Arbitrary Continuous-Variable Encoding

    NASA Astrophysics Data System (ADS)

    Lau, Hoi-Kwan; Plenio, Martin B.

    2016-09-01

    Implementing a qubit quantum computer in continuous-variable systems conventionally requires the engineering of specific interactions according to the encoding basis states. In this work, we present a unified formalism to conduct universal quantum computation with a fixed set of operations but arbitrary encoding. By storing a qubit in the parity of two or four qumodes, all computing processes can be implemented by basis state preparations, continuous-variable exponential-swap operations, and swap tests. Our formalism inherits the advantages that the quantum information is decoupled from collective noise, and logical qubits with different encodings can be brought to interact without decoding. We also propose a possible implementation of the required operations by using interactions that are available in a variety of continuous-variable systems. Our work separates the "hardware" problem of engineering quantum-computing-universal interactions, from the "software" problem of designing encodings for specific purposes. The development of quantum computer architecture could hence be simplified.

  4. Design, construction, operation and costs of a modern small-scale fuel-alcohol plant

    NASA Astrophysics Data System (ADS)

    Leeper, S. A.; Dawley, L. J.; Wolfram, J. H.; Berglund, G. R.; Richardson, J. G.; McAtee, R. E.

    1982-01-01

    The design used for the small-scale fuel alcohol plant (SSFAP) is discussed. By incorporating a microprocessor into the plant design, most plant operations were automated and labor requirements were reduced. Continuous processing made energy conservation possible, thus reducing energy requirements. A low-temperature, continuous plug-flow cooker design made high yields possible. Ethanol was consistently produced at the SSFAP from corn at a yield of 2.6 gallons (anhydrous) per bushel and an energy requirement of 30,000 to 35,000 Btu/gallon (190-proof). In addition, barley, grain dust, and potato waste were converted at the SSFAP. The capacity of the SSFAP is 180,000 gallons per year (300 days operation). Competitively priced ethanol is produced at this capacity.

  5. Identification of emergent off-nominal operational requirements during conceptual architecting of the more electric aircraft

    NASA Astrophysics Data System (ADS)

    Armstrong, Michael James

    Increases in power demands and changes in the design practices of overall equipment manufacturers has led to a new paradigm in vehicle systems definition. The development of unique power systems architectures is of increasing importance to overall platform feasibility and must be pursued early in the aircraft design process. Many vehicle systems architecture trades must be conducted concurrent to platform definition. With an increased complexity introduced during conceptual design, accurate predictions of unit level sizing requirements must be made. Architecture specific emergent requirements must be identified which arise due to the complex integrated effect of unit behaviors. Off-nominal operating scenarios present sizing critical requirements to the aircraft vehicle systems. These requirements are architecture specific and emergent. Standard heuristically defined failure mitigation is sufficient for sizing traditional and evolutionary architectures. However, architecture concepts which vary significantly in terms of structure and composition require that unique failure mitigation strategies be defined for accurate estimations of unit level requirements. Identifying of these off-nominal emergent operational requirements require extensions to traditional safety and reliability tools and the systematic identification of optimal performance degradation strategies. Discrete operational constraints posed by traditional Functional Hazard Assessment (FHA) are replaced by continuous relationships between function loss and operational hazard. These relationships pose the objective function for hazard minimization. Load shedding optimization is performed for all statistically significant failures by varying the allocation of functional capability throughout the vehicle systems architecture. Expressing hazards, and thereby, reliability requirements as continuous relationships with the magnitude and duration of functional failure requires augmentations to the traditional means for system safety assessment (SSA). The traditional two state and discrete system reliability assessment proves insufficient. Reliability is, therefore, handled in an analog fashion: as a function of magnitude of failure and failure duration. A series of metrics are introduced which characterize system performance in terms of analog hazard probabilities. These include analog and cumulative system and functional risk, hazard correlation, and extensions to the traditional component importance metrics. Continuous FHA, load shedding optimization, and analog SSA constitute the SONOMA process (Systematic Off-Nominal Requirements Analysis). Analog system safety metrics inform both architecture optimization (changes in unit level capability and reliability) and architecture augmentation (changes in architecture structure and composition). This process was applied for two vehicle systems concepts (conventional and 'more-electric') in terms of loss/hazard relationships with varying degrees of fidelity. Application of this process shows that the traditional assumptions regarding the structure of the function loss vs. hazard relationship apply undue design bias to functions and components during exploratory design. This bias is illustrated in terms of inaccurate estimations of the system and function level risk and unit level importance. It was also shown that off-nominal emergent requirements must be defined specific to each architecture concept. Quantitative comparisons of architecture specific off-nominal performance were obtained which provide evidence to the need for accurate definition of load shedding strategies during architecture exploratory design. Formally expressing performance degradation strategies in terms of the minimization of a continuous hazard space enhances the system architects ability to accurately predict sizing critical emergent requirements concurrent to architecture definition. Furthermore, the methods and frameworks generated here provide a structured and flexible means for eliciting these architecture specific requirements during the performance of architecture trades.

  6. Processing lunar soils for oxygen and other materials

    NASA Technical Reports Server (NTRS)

    Knudsen, Christian W.; Gibson, Michael A.

    1992-01-01

    Two types of lunar materials are excellent candidates for lunar oxygen production: ilmenite and silicates such as anorthite. Both are lunar surface minable, occurring in soils, breccias, and basalts. Because silicates are considerably more abundant than ilmenite, they may be preferred as source materials. Depending on the processing method chosen for oxygen production and the feedstock material, various useful metals and bulk materials can be produced as byproducts. Available processing techniques include hydrogen reduction of ilmenite and electrochemical and chemical reductions of silicates. Processes in these categories are generally in preliminary development stages and need significant research and development support to carry them to practical deployment, particularly as a lunar-based operation. The goal of beginning lunar processing operations by 2010 requires that planning and research and development emphasize the simplest processing schemes. However, more complex schemes that now appear to present difficult technical challenges may offer more valuable metal byproducts later. While they require more time and effort to perfect, the more complex or difficult schemes may provide important processing and product improvements with which to extend and elaborate the initial lunar processing facilities. A balanced R&D program should take this into account. The following topics are discussed: (1) ilmenite--semi-continuous process; (2) ilmenite--continuous fluid-bed reduction; (3) utilization of spent ilmenite to produce bulk materials; (4) silicates--electrochemical reduction; and (5) silicates--chemical reduction.

  7. 40 CFR 60.276a - Recordkeeping and reporting requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... device, and continuous monitoring equipment; (4) Flow diagram of process and emission capture equipment... at values exceeding ±15 percent of the value established under § 60.274a(c) or operation at flow...

  8. 40 CFR 60.276a - Recordkeeping and reporting requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... device, and continuous monitoring equipment; (4) Flow diagram of process and emission capture equipment... at values exceeding ±15 percent of the value established under § 60.274a(c) or operation at flow...

  9. 40 CFR 60.276a - Recordkeeping and reporting requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... device, and continuous monitoring equipment; (4) Flow diagram of process and emission capture equipment... at values exceeding ±15 percent of the value established under § 60.274a(c) or operation at flow...

  10. 40 CFR 60.276a - Recordkeeping and reporting requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... device, and continuous monitoring equipment; (4) Flow diagram of process and emission capture equipment... at values exceeding ±15 percent of the value established under § 60.274a(c) or operation at flow...

  11. 40 CFR 60.276a - Recordkeeping and reporting requirements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... device, and continuous monitoring equipment; (4) Flow diagram of process and emission capture equipment... at values exceeding ±15 percent of the value established under § 60.274a(c) or operation at flow...

  12. Continuous welding of unidirectional fiber reinforced thermoplastic tape material

    NASA Astrophysics Data System (ADS)

    Schledjewski, Ralf

    2017-10-01

    Continuous welding techniques like thermoplastic tape placement with in situ consolidation offer several advantages over traditional manufacturing processes like autoclave consolidation, thermoforming, etc. However, still there is a need to solve several important processing issues before it becomes a viable economic process. Intensive process analysis and optimization has been carried out in the past through experimental investigation, model definition and simulation development. Today process simulation is capable to predict resulting consolidation quality. Effects of material imperfections or process parameter variations are well known. But using this knowledge to control the process based on online process monitoring and according adaption of the process parameters is still challenging. Solving inverse problems and using methods for automated code generation allowing fast implementation of algorithms on targets are required. The paper explains the placement technique in general. Process-material-property-relationships and typical material imperfections are described. Furthermore, online monitoring techniques and how to use them for a model based process control system are presented.

  13. Continuous Codes and Standards Improvement (CCSI)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rivkin, Carl H; Burgess, Robert M; Buttner, William J

    2015-10-21

    As of 2014, the majority of the codes and standards required to initially deploy hydrogen technologies infrastructure in the United States have been promulgated. These codes and standards will be field tested through their application to actual hydrogen technologies projects. Continuous codes and standards improvement (CCSI) is a process of identifying code issues that arise during project deployment and then developing codes solutions to these issues. These solutions would typically be proposed amendments to codes and standards. The process is continuous because as technology and the state of safety knowledge develops there will be a need to monitor the applicationmore » of codes and standards and improve them based on information gathered during their application. This paper will discuss code issues that have surfaced through hydrogen technologies infrastructure project deployment and potential code changes that would address these issues. The issues that this paper will address include (1) setback distances for bulk hydrogen storage, (2) code mandated hazard analyses, (3) sensor placement and communication, (4) the use of approved equipment, and (5) system monitoring and maintenance requirements.« less

  14. Classification of cardiac arrhythmias using competitive networks.

    PubMed

    Leite, Cicilia R M; Martin, Daniel L; Sizilio, Glaucia R A; Dos Santos, Keylly E A; de Araujo, Bruno G; Valentim, Ricardo A M; Neto, Adriao D D; de Melo, Jorge D; Guerreiro, Ana M G

    2010-01-01

    Information generated by sensors that collect a patient's vital signals are continuous and unlimited data sequences. Traditionally, this information requires special equipment and programs to monitor them. These programs process and react to the continuous entry of data from different origins. Thus, the purpose of this study is to analyze the data produced by these biomedical devices, in this case the electrocardiogram (ECG). Processing uses a neural classifier, Kohonen competitive neural networks, detecting if the ECG shows any cardiac arrhythmia. In fact, it is possible to classify an ECG signal and thereby detect if it is exhibiting or not any alteration, according to normality.

  15. Hydrocarbon fuels from brown grease: Moving from the research laboratory toward an industrial process

    NASA Astrophysics Data System (ADS)

    Pratt, Lawrence M.; Strothers, Joel; Pinnock, Travis; Hilaire, Dickens Saint; Bacolod, Beatrice; Cai, Zhuo Biao; Sim, Yoke-Leng

    2017-04-01

    Brown grease is a generic term for the oily solids and semi-solids that accumulate in the sewer system and in sewage treatment plants. It has previously been shown that brown grease undergoes pyrolysis to form a homologous series of alkanes and 1-alkenes between 7 and 17 carbon atoms, with smaller amounts of higher hydrocarbons and ketones up to about 30 carbon atoms. The initial study was performed in batch mode on a scale of up to 50 grams of starting material. However, continuous processes are usually more efficient for large scale production of fuels and commodity chemicals. This work describes the research and development of a continuous process. The first step was to determine the required reactor temperature. Brown grease consists largely of saturated and unsaturated fatty acids, and they react at different rates, and produce different products and intermediates. Intermediates include ketones, alcohols, and aldehydes, and Fe(III) ion catalyzes at least some of the reactions. By monitoring the pyrolysis of brown grease, its individual components, and intermediates, it was determined that a reactor temperature of at least 340 °C is required. A small scale (1 L) continuous stirred tank reactor was built and its performance is described.

  16. Study on Capturing Functional Requirements of the New Product Based on Evolution

    NASA Astrophysics Data System (ADS)

    Liu, Fang; Song, Liya; Bai, Zhonghang; Zhang, Peng

    In order to exist in an increasingly competitive global marketplace, it is important for corporations to forecast the evolutionary direction of new products rapidly and effectively. Most products in the world are developed based on the design of existing products. In the product design, capturing functional requirements is a key step. Function is continuously evolving, which is driven by the evolution of needs and technologies. So the functional requirements of new product can be forecasted based on the functions of existing product. Eight laws of function evolution are put forward in this paper. The process model of capturing the functional requirements of new product based on function evolution is proposed. An example illustrates the design process.

  17. Plasma separation

    NASA Technical Reports Server (NTRS)

    Steurer, Wolfgang

    1992-01-01

    This process employs a thermal plasma for the separation and production of oxygen and metals. It is a continuous process that requires no consumables and relies entirely on space resources. The almost complete absence of waste renders it relatively clean. It can be turned on or off without any undesirable side effects or residues. The prime disadvantage is its high power consumption.

  18. Application of enhanced modern structured analysis techniques to Space Station Freedom electric power system requirements

    NASA Technical Reports Server (NTRS)

    Biernacki, John; Juhasz, John; Sadler, Gerald

    1991-01-01

    A team of Space Station Freedom (SSF) system engineers are in the process of extensive analysis of the SSF requirements, particularly those pertaining to the electrical power system (EPS). The objective of this analysis is the development of a comprehensive, computer-based requirements model, using an enhanced modern structured analysis methodology (EMSA). Such a model provides a detailed and consistent representation of the system's requirements. The process outlined in the EMSA methodology is unique in that it allows the graphical modeling of real-time system state transitions, as well as functional requirements and data relationships, to be implemented using modern computer-based tools. These tools permit flexible updating and continuous maintenance of the models. Initial findings resulting from the application of EMSA to the EPS have benefited the space station program by linking requirements to design, providing traceability of requirements, identifying discrepancies, and fostering an understanding of the EPS.

  19. Continuous care and patients' basic needs during weaning from mechanical ventilation: A qualitative study.

    PubMed

    Khalafi, Ali; Elahi, Nasrin; Ahmadi, Fazlollah

    2016-12-01

    Mechanical ventilation is associated with a number of risks and complications. Thus, rapid and safe weaning from mechanical ventilation is of great importance. Weaning is a complex and challenging process, requiring continuous care and knowledge of the patient. The aim of the present study was to describe the continuous care process during weaning as well as to analyse the facilitators and obstacles to the weaning process from start to finish from the perspective of intensive care unit (ICU) staff, particularly nurses. Twenty-two ICU staff members, including nurses and physicians, and three patients hospitalised in the ICU were enrolled in this qualitative study. Semi-structured interviews were used for data collection and the transcripts were analysed using qualitative content analysis. 'Continuous care' was found to be the patients' basic need during weaning from mechanical ventilation. Uninterrupted, stable, comprehensive and dynamic care and monitoring with immediate response to all physiological and psychological changes were features of continuous care. The three main themes identified by this study were time spent with the patient, comprehensive supervision and maintenance of the quality of care during shifts. Continuous and constant care should be provided during the weaning process. Such care will help to provide health care staff with a deeper understanding of the patient and his or her continuous changes, leading to a timely and favourable response during weaning. To achieve this goal, skill, communication and organisational changes are essential. Copyright © 2016 Elsevier Ltd. All rights reserved.

  20. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Smith, Donald F.; Schulz, Carl; Konijnenburg, Marco

    High-resolution Fourier transform ion cyclotron resonance (FT-ICR) mass spectrometry imaging enables the spatial mapping and identification of biomolecules from complex surfaces. The need for long time-domain transients, and thus large raw file sizes, results in a large amount of raw data (“big data”) that must be processed efficiently and rapidly. This can be compounded by largearea imaging and/or high spatial resolution imaging. For FT-ICR, data processing and data reduction must not compromise the high mass resolution afforded by the mass spectrometer. The continuous mode “Mosaic Datacube” approach allows high mass resolution visualization (0.001 Da) of mass spectrometry imaging data, butmore » requires additional processing as compared to featurebased processing. We describe the use of distributed computing for processing of FT-ICR MS imaging datasets with generation of continuous mode Mosaic Datacubes for high mass resolution visualization. An eight-fold improvement in processing time is demonstrated using a Dutch nationally available cloud service.« less

  1. General simulation algorithm for autocorrelated binary processes.

    PubMed

    Serinaldi, Francesco; Lombardo, Federico

    2017-02-01

    The apparent ubiquity of binary random processes in physics and many other fields has attracted considerable attention from the modeling community. However, generation of binary sequences with prescribed autocorrelation is a challenging task owing to the discrete nature of the marginal distributions, which makes the application of classical spectral techniques problematic. We show that such methods can effectively be used if we focus on the parent continuous process of beta distributed transition probabilities rather than on the target binary process. This change of paradigm results in a simulation procedure effectively embedding a spectrum-based iterative amplitude-adjusted Fourier transform method devised for continuous processes. The proposed algorithm is fully general, requires minimal assumptions, and can easily simulate binary signals with power-law and exponentially decaying autocorrelation functions corresponding, for instance, to Hurst-Kolmogorov and Markov processes. An application to rainfall intermittency shows that the proposed algorithm can also simulate surrogate data preserving the empirical autocorrelation.

  2. Mathematical Models of Continuous Flow Electrophoresis

    NASA Technical Reports Server (NTRS)

    Saville, D. A.; Snyder, R. S.

    1985-01-01

    Development of high resolution continuous flow electrophoresis devices ultimately requires comprehensive understanding of the ways various phenomena and processes facilitate or hinder separation. A comprehensive model of the actual three dimensional flow, temperature and electric fields was developed to provide guidance in the design of electrophoresis chambers for specific tasks and means of interpreting test data on a given chamber. Part of the process of model development includes experimental and theoretical studies of hydrodynamic stability. This is necessary to understand the origin of mixing flows observed with wide gap gravitational effects. To insure that the model accurately reflects the flow field and particle motion requires extensive experimental work. Another part of the investigation is concerned with the behavior of concentrated sample suspensions with regard to sample stream stability particle-particle interactions which might affect separation in an electric field, especially at high field strengths. Mathematical models will be developed and tested to establish the roles of the various interactions.

  3. Event-driven processing for hardware-efficient neural spike sorting

    NASA Astrophysics Data System (ADS)

    Liu, Yan; Pereira, João L.; Constandinou, Timothy G.

    2018-02-01

    Objective. The prospect of real-time and on-node spike sorting provides a genuine opportunity to push the envelope of large-scale integrated neural recording systems. In such systems the hardware resources, power requirements and data bandwidth increase linearly with channel count. Event-based (or data-driven) processing can provide here a new efficient means for hardware implementation that is completely activity dependant. In this work, we investigate using continuous-time level-crossing sampling for efficient data representation and subsequent spike processing. Approach. (1) We first compare signals (synthetic neural datasets) encoded with this technique against conventional sampling. (2) We then show how such a representation can be directly exploited by extracting simple time domain features from the bitstream to perform neural spike sorting. (3) The proposed method is implemented in a low power FPGA platform to demonstrate its hardware viability. Main results. It is observed that considerably lower data rates are achievable when using 7 bits or less to represent the signals, whilst maintaining the signal fidelity. Results obtained using both MATLAB and reconfigurable logic hardware (FPGA) indicate that feature extraction and spike sorting accuracies can be achieved with comparable or better accuracy than reference methods whilst also requiring relatively low hardware resources. Significance. By effectively exploiting continuous-time data representation, neural signal processing can be achieved in a completely event-driven manner, reducing both the required resources (memory, complexity) and computations (operations). This will see future large-scale neural systems integrating on-node processing in real-time hardware.

  4. Advanced manufacturing development of a composite empennage component for L-1011 aircraft

    NASA Technical Reports Server (NTRS)

    1978-01-01

    Work continued toward the development of tooling and processing concepts required for a cocured hat/skin cover assembly. A plan was developed and implemented to develop the process for using preimpregnated T300/5208 with a resin content of 34 + or - 2 percent by weight. Use of this material results in a simplified laminating process because removal by bleeding or prebleeding is no longer required. The approach to this task basically consists of fabricating and testing flat laminated panels and simulated structural panels to verify known processing techniques relative to end-laminate quality. The flat panels were used to determine air bleeding arrangement and required cure cycle. Single and multihat-stiffened panels were fabricated using the established air bleeding arrangement and cure cycle with the resulting cured parts yielding excellent correlation of ply thickness with all surfaces clear of porosity and voids.

  5. A hybrid continuous-discrete method for stochastic reaction-diffusion processes.

    PubMed

    Lo, Wing-Cheong; Zheng, Likun; Nie, Qing

    2016-09-01

    Stochastic fluctuations in reaction-diffusion processes often have substantial effect on spatial and temporal dynamics of signal transductions in complex biological systems. One popular approach for simulating these processes is to divide the system into small spatial compartments assuming that molecules react only within the same compartment and jump between adjacent compartments driven by the diffusion. While the approach is convenient in terms of its implementation, its computational cost may become prohibitive when diffusive jumps occur significantly more frequently than reactions, as in the case of rapid diffusion. Here, we present a hybrid continuous-discrete method in which diffusion is simulated using continuous approximation while reactions are based on the Gillespie algorithm. Specifically, the diffusive jumps are approximated as continuous Gaussian random vectors with time-dependent means and covariances, allowing use of a large time step, even for rapid diffusion. By considering the correlation among diffusive jumps, the approximation is accurate for the second moment of the diffusion process. In addition, a criterion is obtained for identifying the region in which such diffusion approximation is required to enable adaptive calculations for better accuracy. Applications to a linear diffusion system and two nonlinear systems of morphogens demonstrate the effectiveness and benefits of the new hybrid method.

  6. An architecture for heuristic control of real-time processes

    NASA Technical Reports Server (NTRS)

    Raulefs, P.; Thorndyke, P. W.

    1987-01-01

    Abstract Process management combines complementary approaches of heuristic reasoning and analytical process control. Management of a continuous process requires monitoring the environment and the controlled system, assessing the ongoing situation, developing and revising planned actions, and controlling the execution of the actions. For knowledge-intensive domains, process management entails the potentially time-stressed cooperation among a variety of expert systems. By redesigning a blackboard control architecture in an object-oriented framework, researchers obtain an approach to process management that considerably extends blackboard control mechanisms and overcomes limitations of blackboard systems.

  7. Enhancing Zeolite Performance by Catalyst Shaping in a Mesoscale Continuous-Flow Diels-Alder Process.

    PubMed

    Seghers, Sofie; Lefevere, Jasper; Mullens, Steven; De Vylder, Anton; Thybaut, Joris W; Stevens, Christian V

    2018-03-26

    In contrast to most lab-scale batch procedures, a continuous-flow implementation requires a thorough consideration of the solid catalyst design. In a previous study, irregular zeolite pellets were applied in a miniaturized continuous-flow reactor for the Diels-Alder reaction in the construction of norbornene scaffolds. After having faced the challenges of continuous operation, the aim of this study is to exploit catalyst structuring. To this end, microspheres with high uniformity and various sphere diameters were synthesized according to the vibrational droplet coagulation method. The influence of the use of these novel zeolite shapes in a mesoscale continuous-flow Diels-Alder process of cyclopentadiene and methyl acrylate is discussed. An impressive enhancement of catalyst lifetime is demonstrated, as even after a doubled process time of 14 h, the microspheres still exceeded the conversion after 7 h when using zeolite pellets by 30 %. A dual reason is found for this beneficial impact of catalyst shaping. The significant improvement in catalyst longevity can be attributed to the interplay of the chemical composition and the porosity structure of the microspheres. © 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  8. 42 CFR 3.102 - Process and requirements for initial and continued listing of PSOs.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... information that is not available to other providers, or affect the independence of PSO operations, management... to information regarding the work and operation of the PSO that is not available to other contracting...

  9. Direct writing of metal nanostructures: lithographic tools for nanoplasmonics research.

    PubMed

    Leggett, Graham J

    2011-03-22

    Continued progress in the fast-growing field of nanoplasmonics will require the development of new methods for the fabrication of metal nanostructures. Optical lithography provides a continually expanding tool box. Two-photon processes, as demonstrated by Shukla et al. (doi: 10.1021/nn103015g), enable the fabrication of gold nanostructures encapsulated in dielectric material in a simple, direct process and offer the prospect of three-dimensional fabrication. At higher resolution, scanning probe techniques enable nanoparticle particle placement by localized oxidation, and near-field sintering of nanoparticulate films enables direct writing of nanowires. Direct laser "printing" of single gold nanoparticles offers a remarkable capability for the controlled fabrication of model structures for fundamental studies, particle-by-particle. Optical methods continue to provide a powerful support for research into metamaterials.

  10. An Interprofessional Approach to Continuing Education With Mass Casualty Simulation: Planning and Execution.

    PubMed

    Saber, Deborah A; Strout, Kelley; Caruso, Lisa Swanson; Ingwell-Spolan, Charlene; Koplovsky, Aiden

    2017-10-01

    Many natural and man-made disasters require the assistance from teams of health care professionals. Knowing that continuing education about disaster simulation training is essential to nursing students, nurses, and emergency first responders (e.g., emergency medical technicians, firefighters, police officers), a university in the northeastern United States planned and implemented an interprofessional mass casualty incident (MCI) disaster simulation using the Project Management Body of Knowledge (PMBOK) management framework. The school of nursing and University Volunteer Ambulance Corps (UVAC) worked together to simulate a bus crash with disaster victim actors to provide continued education for community first responders and train nursing students on the MCI process. This article explains the simulation activity, planning process, and achieved outcomes. J Contin Educ Nurs. 2017;48(10):447-453. Copyright 2017, SLACK Incorporated.

  11. Novel method to sample very high power CO2 lasers: II Continuing Studies

    NASA Astrophysics Data System (ADS)

    Eric, John; Seibert, Daniel B., II; Green, Lawrence I.

    2005-04-01

    For the past 28 years, the Laser Hardened Materials Evaluation Laboratory (LHMEL) at the Wright-Patterson Air Force Base, OH, has worked with CO2 lasers capable of producing continuous energy up to 150 kW. These lasers are used in a number of advanced materials processing applications that require accurate spatial energy measurements of the laser. Conventional non-electronic methods are not satisfactory for determining the spatial energy profile. This paper describes continuing efforts in qualifying the new method in which a continuous, real-time electronic spatial energy profile can be obtained for very high power, (VHP) CO2 lasers.

  12. From Prime to Extended Mission: Evolution of the MER Tactical Uplink Process

    NASA Technical Reports Server (NTRS)

    Mishkin, Andrew H.; Laubach, Sharon

    2006-01-01

    To support a 90-day surface mission for two robotic rovers, the Mars Exploration Rover mission designed and implemented an intensive tactical operations process, enabling daily commanding of each rover. Using a combination of new processes, custom software tools, a Mars-time staffing schedule, and seven-day-a-week operations, the MER team was able to compress the traditional weeks-long command-turnaround for a deep space robotic mission to about 18 hours. However, the pace of this process was never intended to be continued indefinitely. Even before the end of the three-month prime mission, MER operations began evolving towards greater sustainability. A combination of continued software tool development, increasing team experience, and availability of reusable sequences first reduced the mean process duration to approximately 11 hours. The number of workshifts required to perform the process dropped, and the team returned to a modified 'Earth-time' schedule. Additional process and tool adaptation eventually provided the option of planning multiple Martian days of activity within a single workshift, making 5-day-a-week operations possible. The vast majority of the science team returned to their home institutions, continuing to participate fully in the tactical operations process remotely. MER has continued to operate for over two Earth-years as many of its key personnel have moved on to other projects, the operations team and budget have shrunk, and the rovers have begun to exhibit symptoms of aging.

  13. The Role of Electronic Health Records in Structuring Nursing Handoff Communication and Maintaining Situation Awareness

    ERIC Educational Resources Information Center

    Alghenaimi, Said

    2012-01-01

    In healthcare institutions, work must continue 24 hours a day, 7 days a week. A team of nurses is needed to provide around-the-clock patient care, and this process requires transfer of patient care responsibilities, a process known as a "handoff." The present study explored the role of electronic health records in structuring handoff…

  14. Knowledge Management Capabilities and Organizational Performance: An Investigation into the Effects of Knowledge Infrastructure and Processes on Organizational Performance

    ERIC Educational Resources Information Center

    Cho, Taejun

    2011-01-01

    Knowledge is one of the most important assets for surviving in the modern business environment. The effective management of that asset mandates continuous adaptation by organizations, and requires employees to strive to improve the company's work processes. Organizations attempt to coordinate their unique knowledge with traditional means as well…

  15. Developing and evaluating innovative items for the NCLEX: Part 2, item characteristics and cognitive processing.

    PubMed

    Wendt, Anne; Harmes, J Christine

    2009-01-01

    This article is a continuation of the research on the development and evaluation of innovative item formats for the NCLEX examinations that was published in the March/April 2009 edition of Nurse Educator. The authors discuss the innovative item templates and evaluate the statistical characteristics and level of cognitive processing required to answer the examination items.

  16. Algae to Bio-Crude in Less Than 60 Minutes

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Elliott, Doug

    Engineers have created a chemical process that produces useful crude oil just minutes after engineers pour in harvested algae -- a verdant green paste with the consistency of pea soup. The PNNL team combined several chemical steps into one continuous process that starts with an algae slurry that contains as much as 80 to 90 percent water. Most current processes require the algae to be dried -- an expensive process that takes a lot of energy. The research has been licensed by Genifuel Corp.

  17. Algae to Bio-Crude in Less Than 60 Minutes

    ScienceCinema

    Elliott, Doug

    2018-01-16

    Engineers have created a chemical process that produces useful crude oil just minutes after engineers pour in harvested algae -- a verdant green paste with the consistency of pea soup. The PNNL team combined several chemical steps into one continuous process that starts with an algae slurry that contains as much as 80 to 90 percent water. Most current processes require the algae to be dried -- an expensive process that takes a lot of energy. The research has been licensed by Genifuel Corp.

  18. Continuous bind-and-elute protein A capture chromatography: Optimization under process scale column constraints and comparison to batch operation.

    PubMed

    Kaltenbrunner, Oliver; Diaz, Luis; Hu, Xiaochun; Shearer, Michael

    2016-07-08

    Recently, continuous downstream processing has become a topic of discussion and analysis at conferences while no industrial applications of continuous downstream processing for biopharmaceutical manufacturing have been reported. There is significant potential to increase the productivity of a Protein A capture step by converting the operation to simulated moving bed (SMB) mode. In this mode, shorter columns are operated at higher process flow and corresponding short residence times. The ability to significantly shorten the product residence time during loading without appreciable capacity loss can dramatically increase productivity of the capture step and consequently reduce the amount of Protein A resin required in the process. Previous studies have not considered the physical limitations of how short columns can be packed and the flow rate limitations due to pressure drop of stacked columns. In this study, we are evaluating the process behavior of a continuous Protein A capture column cycling operation under the known pressure drop constraints of a compressible media. The results are compared to the same resin operated under traditional batch operating conditions. We analyze the optimum system design point for a range of feed concentrations, bed heights, and load residence times and determine achievable productivity for any feed concentration and any column bed height. © 2016 American Institute of Chemical Engineers Biotechnol. Prog., 32:938-948, 2016. © 2016 American Institute of Chemical Engineers.

  19. Influences of operational parameters on phosphorus removal in batch and continuous electrocoagulation process performance.

    PubMed

    Nguyen, Dinh Duc; Yoon, Yong Soo; Bui, Xuan Thanh; Kim, Sung Su; Chang, Soon Woong; Guo, Wenshan; Ngo, Huu Hao

    2017-11-01

    Performance of an electrocoagulation (EC) process in batch and continuous operating modes was thoroughly investigated and evaluated for enhancing wastewater phosphorus removal under various operating conditions, individually or combined with initial phosphorus concentration, wastewater conductivity, current density, and electrolysis times. The results revealed excellent phosphorus removal (72.7-100%) for both processes within 3-6 min of electrolysis, with relatively low energy requirements, i.e., less than 0.5 kWh/m 3 for treated wastewater. However, the removal efficiency of phosphorus in the continuous EC operation mode was better than that in batch mode within the scope of the study. Additionally, the rate and efficiency of phosphorus removal strongly depended on operational parameters, including wastewater conductivity, initial phosphorus concentration, current density, and electrolysis time. Based on experimental data, statistical model verification of the response surface methodology (RSM) (multiple factor optimization) was also established to provide further insights and accurately describe the interactive relationship between the process variables, thus optimizing the EC process performance. The EC process using iron electrodes is promising for improving wastewater phosphorus removal efficiency, and RSM can be a sustainable tool for predicting the performance of the EC process and explaining the influence of the process variables.

  20. Tracking Data Acquisition System (TDAS) for the 1990's. Volume 6: TDAS navigation system architecture

    NASA Technical Reports Server (NTRS)

    Elrod, B. D.; Jacobsen, A.; Cook, R. A.; Singh, R. N. P.

    1983-01-01

    One-way range and Doppler methods for providing user orbit and time determination are examined. Forward link beacon tracking, with on-board processing of independent navigation signals broadcast continuously by TDAS spacecraft; forward link scheduled tracking; with on-board processing of navigation data received during scheduled TDAS forward link service intervals; and return link scheduled tracking; with ground-based processing of user generated navigation data during scheduled TDAS return link service intervals are discussed. A system level definition and requirements assessment for each alternative, an evaluation of potential navigation performance and comparison with TDAS mission model requirements is included. TDAS satellite tracking is also addressed for two alternatives: BRTS and VLBI tracking.

  1. Supercritical fluids as alternative, safe, food-processing media: an overview.

    PubMed

    Da Cruz Francisco, José; Szwajcer Dey, Estera

    2003-01-01

    The continuous growth of world population and its concentration in the urban areas require food supplies that are continuous, sufficient and of good quality. To resolve this problem techniques have been developed for increasing food quantity and quality. The techniques are applied throughout the food chain from production, conservation and during distribution to the consumers (from "the field to the fork"). During handling of food, chemicals are often deliberately added to achieve improved processing and better quality. This is one of the main reasons food undergoes different kinds of contamination. This overview focuses on the application of supercritical fluids as media for handling food materials during processing with the perspective of reducing chemical contamination of food. Examples of developmental applications of this technique and on research work in process are presented. Emphasis is given to extraction and biotransformation techniques.

  2. African Union: Towards Good Governance, Peace and Security

    DTIC Science & Technology

    2012-03-15

    While good governance, peace and security remain individual state responsibilities, they constitute the main pillars of Africa’s political stability and...African national leadership to drive this process.2 Political stability itself requires strong state institutional capabilities to ensure continuity

  3. 40 CFR 240.209 - Safety.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Safety. 240.209 Section 240.209 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.209 Safety. ...

  4. BTS guide to good statistical practice

    DOT National Transportation Integrated Search

    2002-09-01

    Quality of data has many faces. Primarily, it has to be relevant to its users. Relevance is : an outcome that is achieved through a series of steps starting with a planning process that : link user needs to data requirements. It continues through acq...

  5. Coaching "Callings" throughout the Adult Life Cycle.

    ERIC Educational Resources Information Center

    Hudson, Frederic M.

    2001-01-01

    The process of "callings" continues throughout life. Coaching can connect the present to the future in a meaningful way. Callings represent a value shift requiring revision of the nature and scope of one's central purpose in life and meaningful activities. (JOW)

  6. 46 CFR 57.03-1 - General requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING WELDING AND BRAZING... welding or brazing procedure specification for the particular welding or brazing process to be used. The welding or brazing procedure specification must include a sketch showing joint preparation. Suggested...

  7. 45 CFR 2400.20 - Preparation of application.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 45 Public Welfare 4 2012-10-01 2012-10-01 false Preparation of application. 2400.20 Section 2400.20 Public Welfare Regulations Relating to Public Welfare (Continued) JAMES MADISON MEMORIAL FELLOWSHIP FOUNDATION FELLOWSHIP PROGRAM REQUIREMENTS Application Process § 2400.20 Preparation of...

  8. 45 CFR 2400.20 - Preparation of application.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 4 2013-10-01 2013-10-01 false Preparation of application. 2400.20 Section 2400.20 Public Welfare Regulations Relating to Public Welfare (Continued) JAMES MADISON MEMORIAL FELLOWSHIP FOUNDATION FELLOWSHIP PROGRAM REQUIREMENTS Application Process § 2400.20 Preparation of...

  9. 45 CFR 2400.22 - Application deadline.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 4 2013-10-01 2013-10-01 false Application deadline. 2400.22 Section 2400.22 Public Welfare Regulations Relating to Public Welfare (Continued) JAMES MADISON MEMORIAL FELLOWSHIP FOUNDATION FELLOWSHIP PROGRAM REQUIREMENTS Application Process § 2400.22 Application deadline. Completed...

  10. 45 CFR 2400.20 - Preparation of application.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 4 2014-10-01 2014-10-01 false Preparation of application. 2400.20 Section 2400.20 Public Welfare Regulations Relating to Public Welfare (Continued) JAMES MADISON MEMORIAL FELLOWSHIP FOUNDATION FELLOWSHIP PROGRAM REQUIREMENTS Application Process § 2400.20 Preparation of...

  11. 45 CFR 2400.22 - Application deadline.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 4 2014-10-01 2014-10-01 false Application deadline. 2400.22 Section 2400.22 Public Welfare Regulations Relating to Public Welfare (Continued) JAMES MADISON MEMORIAL FELLOWSHIP FOUNDATION FELLOWSHIP PROGRAM REQUIREMENTS Application Process § 2400.22 Application deadline. Completed...

  12. 45 CFR 2400.22 - Application deadline.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 45 Public Welfare 4 2012-10-01 2012-10-01 false Application deadline. 2400.22 Section 2400.22 Public Welfare Regulations Relating to Public Welfare (Continued) JAMES MADISON MEMORIAL FELLOWSHIP FOUNDATION FELLOWSHIP PROGRAM REQUIREMENTS Application Process § 2400.22 Application deadline. Completed...

  13. 45 CFR 2400.20 - Preparation of application.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 4 2011-10-01 2011-10-01 false Preparation of application. 2400.20 Section 2400.20 Public Welfare Regulations Relating to Public Welfare (Continued) JAMES MADISON MEMORIAL FELLOWSHIP FOUNDATION FELLOWSHIP PROGRAM REQUIREMENTS Application Process § 2400.20 Preparation of...

  14. 45 CFR 2400.22 - Application deadline.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 4 2011-10-01 2011-10-01 false Application deadline. 2400.22 Section 2400.22 Public Welfare Regulations Relating to Public Welfare (Continued) JAMES MADISON MEMORIAL FELLOWSHIP FOUNDATION FELLOWSHIP PROGRAM REQUIREMENTS Application Process § 2400.22 Application deadline. Completed...

  15. 45 CFR 2400.20 - Preparation of application.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 4 2010-10-01 2010-10-01 false Preparation of application. 2400.20 Section 2400.20 Public Welfare Regulations Relating to Public Welfare (Continued) JAMES MADISON MEMORIAL FELLOWSHIP FOUNDATION FELLOWSHIP PROGRAM REQUIREMENTS Application Process § 2400.20 Preparation of...

  16. 45 CFR 2400.22 - Application deadline.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 4 2010-10-01 2010-10-01 false Application deadline. 2400.22 Section 2400.22 Public Welfare Regulations Relating to Public Welfare (Continued) JAMES MADISON MEMORIAL FELLOWSHIP FOUNDATION FELLOWSHIP PROGRAM REQUIREMENTS Application Process § 2400.22 Application deadline. Completed...

  17. 40 CFR 240.207 - Aesthetics.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Aesthetics. 240.207 Section 240.207 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.207 Aesthetics. ...

  18. 40 CFR 240.208 - Residue.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Residue. 240.208 Section 240.208 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.208 Residue. ...

  19. 40 CFR 240.206 - Vectors.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Vectors. 240.206 Section 240.206 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.206 Vectors. ...

  20. 40 CFR 240.211 - Records.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Records. 240.211 Section 240.211 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.211 Records. ...

  1. 40 CFR 141.130 - General requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... (CONTINUED) NATIONAL PRIMARY DRINKING WATER REGULATIONS Disinfectant Residuals, Disinfection Byproducts, and... constitute national primary drinking water regulations. (1) The regulations in this subpart establish...) which add a chemical disinfectant to the water in any part of the drinking water treatment process must...

  2. 40 CFR 240.205-2 - Recommended procedures: Design.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ....205-2 Section 240.205-2 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures... air pollution control technology. (b) All emissions, including dust from vents, should be controlled. ...

  3. 40 CFR 240.205-2 - Recommended procedures: Design.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ....205-2 Section 240.205-2 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures... air pollution control technology. (b) All emissions, including dust from vents, should be controlled. ...

  4. 40 CFR 240.209 - Safety.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Safety. 240.209 Section 240.209 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.209 Safety. ...

  5. 40 CFR 240.211 - Records.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Records. 240.211 Section 240.211 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.211 Records. ...

  6. 40 CFR 240.211 - Records.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Records. 240.211 Section 240.211 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.211 Records. ...

  7. 40 CFR 240.211 - Records.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Records. 240.211 Section 240.211 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.211 Records. ...

  8. 46 CFR 57.03-1 - General requirements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING WELDING AND BRAZING... welding or brazing procedure specification for the particular welding or brazing process to be used. The welding or brazing procedure specification must include a sketch showing joint preparation. Suggested...

  9. 46 CFR 57.03-1 - General requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING WELDING AND BRAZING... welding or brazing procedure specification for the particular welding or brazing process to be used. The welding or brazing procedure specification must include a sketch showing joint preparation. Suggested...

  10. 46 CFR 57.03-1 - General requirements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING WELDING AND BRAZING... welding or brazing procedure specification for the particular welding or brazing process to be used. The welding or brazing procedure specification must include a sketch showing joint preparation. Suggested...

  11. 46 CFR 57.03-1 - General requirements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING WELDING AND BRAZING... welding or brazing procedure specification for the particular welding or brazing process to be used. The welding or brazing procedure specification must include a sketch showing joint preparation. Suggested...

  12. 40 CFR 61.356 - Recordkeeping requirements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ..., annual average flow-weighted benzene concentration, and annual benzene quantity. (2) For each waste... measurements, calculations, and other documentation used to determine that the continuous flow of process... benzene concentrations in the waste, the annual average flow-weighted benzene concentration of the waste...

  13. 40 CFR 61.356 - Recordkeeping requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ..., annual average flow-weighted benzene concentration, and annual benzene quantity. (2) For each waste... measurements, calculations, and other documentation used to determine that the continuous flow of process... benzene concentrations in the waste, the annual average flow-weighted benzene concentration of the waste...

  14. 40 CFR 61.356 - Recordkeeping requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ..., annual average flow-weighted benzene concentration, and annual benzene quantity. (2) For each waste... measurements, calculations, and other documentation used to determine that the continuous flow of process... benzene concentrations in the waste, the annual average flow-weighted benzene concentration of the waste...

  15. 45 CFR 800.301 - Application process.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Public Welfare Regulations Relating to Public Welfare (Continued) OFFICE OF PERSONNEL MANAGEMENT MULTI... statute requiring competitive bidding, OPM may consider annually applications from health insurance issuers, including groups of health insurance issuers as defined in § 800.20, to participate in the MSPP...

  16. 40 CFR 725.70 - Compliance.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 30 2010-07-01 2010-07-01 false Compliance. 725.70 Section 725.70 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT REPORTING REQUIREMENTS AND REVIEW PROCESSES FOR MICROORGANISMS Administrative Procedures § 725.70 Compliance. (a) Failure...

  17. 40 CFR 725.70 - Compliance.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 31 2011-07-01 2011-07-01 false Compliance. 725.70 Section 725.70 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT REPORTING REQUIREMENTS AND REVIEW PROCESSES FOR MICROORGANISMS Administrative Procedures § 725.70 Compliance. (a) Failure...

  18. Production process stability - core assumption of INDUSTRY 4.0 concept

    NASA Astrophysics Data System (ADS)

    Chromjakova, F.; Bobak, R.; Hrusecka, D.

    2017-06-01

    Today’s industrial enterprises are confronted by implementation of INDUSTRY 4.0 concept with basic problem - stabilised manufacturing and supporting processes. Through this phenomenon of stabilisation, they will achieve positive digital management of both processes and continuously throughput. There is required structural stability of horizontal (business) and vertical (digitized) manufacturing processes, supported through digitalised technologies of INDUSTRY 4.0 concept. Results presented in this paper based on the research results and survey realised in more industrial companies. Following will described basic model for structural process stabilisation in manufacturing environment.

  19. Future Supply Chains Enabled by Continuous Processing-Opportunities Challenges May 20-21 2014 Continuous Manufacturing Symposium.

    PubMed

    Srai, Jagjit Singh; Badman, Clive; Krumme, Markus; Futran, Mauricio; Johnston, Craig

    2015-03-01

    This paper examines the opportunities and challenges facing the pharmaceutical industry in moving to a primarily "continuous processing"-based supply chain. The current predominantly "large batch" and centralized manufacturing system designed for the "blockbuster" drug has driven a slow-paced, inventory heavy operating model that is increasingly regarded as inflexible and unsustainable. Indeed, new markets and the rapidly evolving technology landscape will drive more product variety, shorter product life-cycles, and smaller drug volumes, which will exacerbate an already unsustainable economic model. Future supply chains will be required to enhance affordability and availability for patients and healthcare providers alike despite the increased product complexity. In this more challenging supply scenario, we examine the potential for a more pull driven, near real-time demand-based supply chain, utilizing continuous processing where appropriate as a key element of a more "flow-through" operating model. In this discussion paper on future supply chain models underpinned by developments in the continuous manufacture of pharmaceuticals, we have set out; The paper recognizes that although current batch operational performance in pharma is far from optimal and not necessarily an appropriate end-state benchmark for batch technology, the adoption of continuous supply chain operating models underpinned by continuous production processing, as full or hybrid solutions in selected product supply chains, can support industry transformations to deliver right-first-time quality at substantially lower inventory profiles. © 2015 The Authors. Journal of Pharmaceutical Sciences published by Wiley Periodicals, Inc. and the American Pharmacists Association. © 2014 Wiley Periodicals, Inc. and the American Pharmacists Association.

  20. The exact fundamental solution for the Benes tracking problem

    NASA Astrophysics Data System (ADS)

    Balaji, Bhashyam

    2009-05-01

    The universal continuous-discrete tracking problem requires the solution of a Fokker-Planck-Kolmogorov forward equation (FPKfe) for an arbitrary initial condition. Using results from quantum mechanics, the exact fundamental solution for the FPKfe is derived for the state model of arbitrary dimension with Benes drift that requires only the computation of elementary transcendental functions and standard linear algebra techniques- no ordinary or partial differential equations need to be solved. The measurement process may be an arbitrary, discrete-time nonlinear stochastic process, and the time step size can be arbitrary. Numerical examples are included, demonstrating its utility in practical implementation.

  1. Subjective Prior Distributions for Modeling Longitudinal Continuous Outcomes with Non-Ignorable Dropout

    PubMed Central

    Paddock, Susan M.; Ebener, Patricia

    2010-01-01

    Substance abuse treatment research is complicated by the pervasive problem of non-ignorable missing data – i.e., the occurrence of the missing data is related to the unobserved outcomes. Missing data frequently arise due to early client departure from treatment. Pattern-mixture models (PMMs) are often employed in such situations to jointly model the outcome and the missing data mechanism. PMMs require non-testable assumptions to identify model parameters. Several approaches to parameter identification have therefore been explored for longitudinal modeling of continuous outcomes, and informative priors have been developed in other contexts. In this paper, we describe an expert interview conducted with five substance abuse treatment clinical experts who have familiarity with the Therapeutic Community modality of substance abuse treatment and with treatment process scores collected using the Dimensions of Change Instrument. The goal of the interviews was to obtain expert opinion about the rate of change in continuous client-level treatment process scores for clients who leave before completing two assessments and whose rate of change (slope) in treatment process scores is unidentified by the data. We find that the experts’ opinions differed dramatically from widely-utilized assumptions used to identify parameters in the PMM. Further, subjective prior assessment allows one to properly address the uncertainty inherent in the subjective decisions required to identify parameters in the PMM and to measure their effect on conclusions drawn from the analysis. PMID:19012279

  2. Design and Implementation of an Innovative Manufacturing Process for Aerial and Land Supply Needs

    DTIC Science & Technology

    2011-06-30

    buildup of the pad , the incoming web should be held in place during cutting operation to eliminate any shifting / tilting , this has been achieved by...the required number of layers of the folded sheets is stacked to meet the desired size of the pad , the finished pad is ejected and the process...continues for making the remaining pads . Development of such innovative manufacturing process provides immediate capability for the Department of

  3. Feasibility of commercial space manufacturing, production of pharmaceuticals. Volume 3: Product data

    NASA Technical Reports Server (NTRS)

    1978-01-01

    The feasibility of commercial manufacturing of pharmaceuticals in space is analyzed and the study results are presented. The chronology of the study process is discussed. The separation of serum proteins by the continuous flow electrophoresis process is investigated. The production requirements of twelve candidate products including antihemophilic factor, beta cells, erythropoietin, epidermal growth factor, alpha-1-antitrypsin, and interferon are evaluated.

  4. 40 CFR 270.30 - Conditions applicable to all permits.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... operator staffing and training, and adequate laboratory and process controls, including appropriate quality... any location. (j) Monitoring and records. (1) Samples and measurements taken for the purpose of... recordings for continuous monitoring instrumentation, copies of all reports required by this permit, the...

  5. 40 CFR 270.30 - Conditions applicable to all permits.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... operator staffing and training, and adequate laboratory and process controls, including appropriate quality... any location. (j) Monitoring and records. (1) Samples and measurements taken for the purpose of... recordings for continuous monitoring instrumentation, copies of all reports required by this permit, the...

  6. 40 CFR 240.204 - Water quality.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Water quality. 240.204 Section 240.204 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.204 Water quality. ...

  7. 40 CFR 240.204 - Water quality.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Water quality. 240.204 Section 240.204 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.204 Water quality. ...

  8. Guide to good statistical practice in the transportation field

    DOT National Transportation Integrated Search

    2003-05-01

    Quality of data has many faces. Primarily, it has to be relevant (i.e., useful) to its users. Relevance is achieved through a series of steps starting with a planning process that links user needs to data requirements. It continues through acquisitio...

  9. Transportation improvement program and air quality conformity determination federal fiscal years 2008-2011

    DOT National Transportation Integrated Search

    2007-01-01

    In order to be eligible for federal funds, urbanized areas are required to maintain a continuing, cooperative, and comprehensive (3C) transportation planning process that results in plans and programs consistent with the planning objectives of the me...

  10. 40 CFR Table 7 to Subpart Ppp of... - Process Vents From Continuous Unit Operations-Monitoring, Recordkeeping, and Reporting Requirements

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... regeneration stream mass or volumetric flow during carbon bed regeneration cycle; and temperature of the carbon bed after regeneration (and within 15 minutes of completing any cooling cycle(s)) Maximum mass or...

  11. 28 CFR 26.22 - Requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Judicial Administration DEPARTMENT OF JUSTICE DEATH SENTENCES PROCEDURES Certification Process for State... of death in state postconviction proceedings. As provided in 28 U.S.C. 2261(c) and (d), the mechanism... represented the prisoner at trial unless the prisoner and counsel expressly request continued representation...

  12. 40 CFR 240.209-2 - Recommended procedures: Design.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Recommended procedures: Design. 240.209-2 Section 240.209-2 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures...

  13. 40 CFR 240.208-3 - Recommended procedures: Operations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Recommended procedures: Operations. 240.208-3 Section 240.208-3 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended...

  14. 40 CFR 240.210-3 - Recommended procedures: Operations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Recommended procedures: Operations. 240.210-3 Section 240.210-3 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended...

  15. 40 CFR 240.210 - General operations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false General operations. 240.210 Section 240.210 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.210 General...

  16. 40 CFR 240.202-3 - Recommended procedures: Operations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Recommended procedures: Operations. 240.202-3 Section 240.202-3 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended...

  17. 40 CFR 240.202-2 - Recommended procedures: Design.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Recommended procedures: Design. 240.202-2 Section 240.202-2 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures...

  18. 40 CFR 240.210-2 - Recommended procedures: Design.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Recommended procedures: Design. 240.210-2 Section 240.210-2 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures...

  19. 40 CFR 240.207-2 - Recommended procedures: Design.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ....207-2 Section 240.207-2 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures... attractive. The tipping, residue discharge, and waste salvage areas should be screened from public view, and...

  20. 40 CFR 240.203-3 - Recommended procedures: Operations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Recommended procedures: Operations. 240.203-3 Section 240.203-3 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended...

  1. 40 CFR 240.206-2 - Recommended procedures: Design.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Recommended procedures: Design. 240.206-2 Section 240.206-2 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures...

  2. 40 CFR 240.205 - Air quality.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Air quality. 240.205 Section 240.205 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.205 Air quality. ...

  3. 40 CFR 240.205 - Air quality.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Air quality. 240.205 Section 240.205 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.205 Air quality. ...

  4. 40 CFR 240.205 - Air quality.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Air quality. 240.205 Section 240.205 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.205 Air quality. ...

  5. 40 CFR 240.205 - Air quality.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Air quality. 240.205 Section 240.205 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.205 Air quality. ...

  6. 40 CFR 240.204 - Water quality.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Water quality. 240.204 Section 240.204 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.204 Water quality. ...

  7. 40 CFR 240.204 - Water quality.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Water quality. 240.204 Section 240.204 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.204 Water quality. ...

  8. 40 CFR 240.204 - Water quality.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Water quality. 240.204 Section 240.204 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.204 Water quality. ...

  9. 40 CFR 240.202-2 - Recommended procedures: Design.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Recommended procedures: Design. 240.202-2 Section 240.202-2 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures...

  10. 40 CFR 240.201-2 - Recommended procedures: Design.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ....201-2 Section 240.201-2 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures... or excluded wastes inadvertently left at the facility should be considered in design. (b) Examples of...

  11. 40 CFR 240.211-2 - Recommended procedures: Design.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Recommended procedures: Design. 240.211-2 Section 240.211-2 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures...

  12. 40 CFR 240.200-2 - Recommended procedures: Design.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ....200-2 Section 240.200-2 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.200-2 Recommended procedures: Design. (a) In addition to the residential and commercial wastes...

  13. 40 CFR 240.202 - Site selection.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Site selection. 240.202 Section 240.202 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.202 Site...

  14. 40 CFR 240.200-2 - Recommended procedures: Design.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ....200-2 Section 240.200-2 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.200-2 Recommended procedures: Design. (a) In addition to the residential and commercial wastes...

  15. 7 CFR 926.9 - Handle.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and... REQUIREMENTS APPLICABLE TO CRANBERRIES NOT SUBJECT TO THE CRANBERRY MARKETING ORDER § 926.9 Handle. Handle... cranberries or processed cranberries up to, but not including, the retail level. Effective Date Note: At 71 FR...

  16. 50 CFR 80.80 - How does an agency apply for a grant?

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... INTERIOR (CONTINUED) FINANCIAL ASSISTANCE-WILDLIFE SPORT FISH RESTORATION PROGRAM ADMINISTRATIVE REQUIREMENTS, PITTMAN-ROBERTSON WILDLIFE RESTORATION AND DINGELL-JOHNSON SPORT FISH RESTORATION ACTS... Management and Budget for the grant application process; and (ii) Available on the Federal Web site for...

  17. 40 CFR 240.205 - Air quality.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Air quality. 240.205 Section 240.205 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.205 Air quality. ...

  18. Continuous and pulsed laser high power beam combiner for additive manufacturing applications

    NASA Astrophysics Data System (ADS)

    Bassignana, Marta; Califano, Alessio; Pescarmona, Francesco; Braglia, Andrea; Perrone, Guido

    2018-02-01

    Laser-based additive manufacturing (AM) from metal powders is emerging as the new industrial revolution, although current fabrication approaches still require long mechanical post-processing to improve the final surface quality and meet the design tolerances. To overcome this limitation, the next generation machines are expected to complement laser AM with laser ablation (LA) to implement surface finishing and micro texturing already during the device growth process. With this aim, a new beam combiner to allow the real-time interchange of additive and subtractive processes using the same scanner head has been designed. Extensive tests have been carried out using a 6 kW continuous-wave laser similar to that used for the metal powder fusion and a nanosecond 100W pulsed source similar to that used for laser ablation.

  19. Comparative technoeconomic analysis of a softwood ethanol process featuring posthydrolysis sugars concentration operations and continuous fermentation with cell recycle.

    PubMed

    Schneiderman, Steven J; Gurram, Raghu N; Menkhaus, Todd J; Gilcrease, Patrick C

    2015-01-01

    Economical production of second generation ethanol from Ponderosa pine is of interest due to widespread mountain pine beetle infestation in the western United States and Canada. The conversion process is limited by low glucose and high inhibitor concentrations resulting from conventional low-solids dilute acid pretreatment and enzymatic hydrolysis. Inhibited fermentations require larger fermentors (due to reduced volumetric productivity) and low sugars lead to low ethanol titers, increasing distillation costs. In this work, multiple effect evaporation (MEE) and nanofiltration (NF) were evaluated to concentrate the hydrolysate from 30 g/l to 100, 150, or 200 g/l glucose. To ferment this high gravity, inhibitor containing stream, traditional batch fermentation was compared with continuous stirred tank fermentation (CSTF) and continuous fermentation with cell recycle (CSTF-CR). Equivalent annual operating cost (EAOC = amortized capital + yearly operating expenses) was used to compare these potential improvements for a local-scale 5 MGY ethanol production facility. Hydrolysate concentration via evaporation increased EAOC over the base process due to the capital and energy intensive nature of evaporating a very dilute sugar stream; however, concentration via NF decreased EAOC for several of the cases (by 2 to 15%). NF concentration to 100 g/l glucose with a CSTF-CR was the most economical option, reducing EAOC by $0.15 per gallon ethanol produced. Sensitivity analyses on NF options showed that EAOC improvement over the base case could still be realized for even higher solids removal requirements (up to two times higher centrifuge requirement for the best case) or decreased NF performance. © 2015 American Institute of Chemical Engineers.

  20. Lapse in Institutional Animal Care and Use Committee Continuing Reviews.

    PubMed

    Tsan, Min-Fu; Grabenbauer, Michael; Nguyen, Yen

    2016-01-01

    The United States federal animal welfare regulations and the Public Health Service Policy on Humane Care and Use of Laboratory Animals require that institutional animal care and use committees (IACUCs) conduct continuing reviews of all animal research activities. However, little is known about the lapse rate of IACUC continuing reviews, and how frequently investigators continue research activities during the lapse. It is also not clear what factors may contribute to an institution's lapse in IACUC continuing reviews. As part of the quality assurance program, the Department of Veterans Affairs (VA) has collected performance metric data for animal care and use programs since 2011. We analyzed IACUC continuing review performance data at 74-75 VA research facilities from 2011 through 2015. The IACUC continuing review lapse rates improved from 5.6% in 2011 to 2.7% in 2015. The rate of investigators continuing research activities during the lapse also decreased from 47.2% in 2012 to 7.4% in 2015. The type of IACUCs used and the size of animal research programs appeared to have no effect in facility's rates of lapse in IACUC continuing reviews. While approximately 80% of facilities reported no lapse in IACUC continuing reviews, approximately 14% of facilities had lapse rates of >10% each year. Some facilities appeared to be repeat offenders. Four facilities had IACUC lapse rates of >10% in at least 3 out of 5 years, suggesting a system problem in these facilities requiring remedial actions to improve their IACUC continuing review processes.

  1. Unlocking the potential of supported liquid phase catalysts with supercritical fluids: low temperature continuous flow catalysis with integrated product separation

    PubMed Central

    Franciò, Giancarlo; Hintermair, Ulrich; Leitner, Walter

    2015-01-01

    Solution-phase catalysis using molecular transition metal complexes is an extremely powerful tool for chemical synthesis and a key technology for sustainable manufacturing. However, as the reaction complexity and thermal sensitivity of the catalytic system increase, engineering challenges associated with product separation and catalyst recovery can override the value of the product. This persistent downstream issue often renders industrial exploitation of homogeneous catalysis uneconomical despite impressive batch performance of the catalyst. In this regard, continuous-flow systems that allow steady-state homogeneous turnover in a stationary liquid phase while at the same time effecting integrated product separation at mild process temperatures represent a particularly attractive scenario. While continuous-flow processing is a standard procedure for large volume manufacturing, capitalizing on its potential in the realm of the molecular complexity of organic synthesis is still an emerging area that requires innovative solutions. Here we highlight some recent developments which have succeeded in realizing such systems by the combination of near- and supercritical fluids with homogeneous catalysts in supported liquid phases. The cases discussed exemplify how all three levels of continuous-flow homogeneous catalysis (catalyst system, separation strategy, process scheme) must be matched to locate viable process conditions. PMID:26574523

  2. A hybrid continuous-discrete method for stochastic reaction–diffusion processes

    PubMed Central

    Zheng, Likun; Nie, Qing

    2016-01-01

    Stochastic fluctuations in reaction–diffusion processes often have substantial effect on spatial and temporal dynamics of signal transductions in complex biological systems. One popular approach for simulating these processes is to divide the system into small spatial compartments assuming that molecules react only within the same compartment and jump between adjacent compartments driven by the diffusion. While the approach is convenient in terms of its implementation, its computational cost may become prohibitive when diffusive jumps occur significantly more frequently than reactions, as in the case of rapid diffusion. Here, we present a hybrid continuous-discrete method in which diffusion is simulated using continuous approximation while reactions are based on the Gillespie algorithm. Specifically, the diffusive jumps are approximated as continuous Gaussian random vectors with time-dependent means and covariances, allowing use of a large time step, even for rapid diffusion. By considering the correlation among diffusive jumps, the approximation is accurate for the second moment of the diffusion process. In addition, a criterion is obtained for identifying the region in which such diffusion approximation is required to enable adaptive calculations for better accuracy. Applications to a linear diffusion system and two nonlinear systems of morphogens demonstrate the effectiveness and benefits of the new hybrid method. PMID:27703710

  3. Unlocking the potential of supported liquid phase catalysts with supercritical fluids: low temperature continuous flow catalysis with integrated product separation.

    PubMed

    Franciò, Giancarlo; Hintermair, Ulrich; Leitner, Walter

    2015-12-28

    Solution-phase catalysis using molecular transition metal complexes is an extremely powerful tool for chemical synthesis and a key technology for sustainable manufacturing. However, as the reaction complexity and thermal sensitivity of the catalytic system increase, engineering challenges associated with product separation and catalyst recovery can override the value of the product. This persistent downstream issue often renders industrial exploitation of homogeneous catalysis uneconomical despite impressive batch performance of the catalyst. In this regard, continuous-flow systems that allow steady-state homogeneous turnover in a stationary liquid phase while at the same time effecting integrated product separation at mild process temperatures represent a particularly attractive scenario. While continuous-flow processing is a standard procedure for large volume manufacturing, capitalizing on its potential in the realm of the molecular complexity of organic synthesis is still an emerging area that requires innovative solutions. Here we highlight some recent developments which have succeeded in realizing such systems by the combination of near- and supercritical fluids with homogeneous catalysts in supported liquid phases. The cases discussed exemplify how all three levels of continuous-flow homogeneous catalysis (catalyst system, separation strategy, process scheme) must be matched to locate viable process conditions. © 2015 The Authors.

  4. Direct approach for bioprocess optimization in a continuous flat-bed photobioreactor system.

    PubMed

    Kwon, Jong-Hee; Rögner, Matthias; Rexroth, Sascha

    2012-11-30

    Application of photosynthetic micro-organisms, such as cyanobacteria and green algae, for the carbon neutral energy production raises the need for cost-efficient photobiological processes. Optimization of these processes requires permanent control of many independent and mutably dependent parameters, for which a continuous cultivation approach has significant advantages. As central factors like the cell density can be kept constant by turbidostatic control, light intensity and iron content with its strong impact on productivity can be optimized. Both are key parameters due to their strong dependence on photosynthetic activity. Here we introduce an engineered low-cost 5 L flat-plate photobioreactor in combination with a simple and efficient optimization procedure for continuous photo-cultivation of microalgae. Based on direct determination of the growth rate at constant cell densities and the continuous measurement of O₂ evolution, stress conditions and their effect on the photosynthetic productivity can be directly observed. Copyright © 2012 Elsevier B.V. All rights reserved.

  5. Life sciences flight experiments program mission science requirements document. The first life sciences dedicated Spacelab mission, part 1

    NASA Technical Reports Server (NTRS)

    Rummel, J. A.

    1982-01-01

    The Mission Science Requirements Document (MSRD) for the First Dedicated Life Sciences Mission (LS-1) represents the culmination of thousands of hours of experiment selection, and science requirement definition activities. NASA life sciences has never before attempted to integrate, both scientifically and operationally, a single mission dedicated to life sciences research, and the complexity of the planning required for such an endeavor should be apparent. This set of requirements completes the first phase of a continual process which will attempt to optimize (within available programmatic and mission resources) the science accomplished on this mission.

  6. 40 CFR 63.1335 - General recordkeeping and reporting provisions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Precompliance Report. The Administrator may deem alternative controls to be equivalent to the controls required... (CONTINUED) National Emission Standards for Hazardous Air Pollutant Emissions: Group IV Polymers and Resins... malfunction and a program for corrective action for malfunctioning process and air pollution control equipment...

  7. 15 CFR Appendix A to Subpart C of... - Certification Application Templates

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... as to the purpose of its products as described in this requirement. (15) Quality management system... certification of compliance with an equivalent program of quality management that covers the processes described... Trade (Continued) NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE QUALITY...

  8. 7 CFR 1780.17 - Selection priorities and process.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...) Projects that primarily recycle solid waste products thereby limiting the need for solid waste disposal—5..., DEPARTMENT OF AGRICULTURE (CONTINUED) WATER AND WASTE LOANS AND GRANTS General Policies and Requirements... solid waste violations—15 points. (c) Median household income priorities. The median household income of...

  9. 7 CFR 1780.17 - Selection priorities and process.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...) Projects that primarily recycle solid waste products thereby limiting the need for solid waste disposal—5..., DEPARTMENT OF AGRICULTURE (CONTINUED) WATER AND WASTE LOANS AND GRANTS General Policies and Requirements... solid waste violations—15 points. (c) Median household income priorities. The median household income of...

  10. 7 CFR 1780.17 - Selection priorities and process.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...) Projects that primarily recycle solid waste products thereby limiting the need for solid waste disposal—5..., DEPARTMENT OF AGRICULTURE (CONTINUED) WATER AND WASTE LOANS AND GRANTS General Policies and Requirements... solid waste violations—15 points. (c) Median household income priorities. The median household income of...

  11. 7 CFR 1160.215 - Assessment exemption.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...) system plan; processes only products that are eligible to be labeled as 100 percent organic under the NOP... Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing... shall be required on fluid milk products exported from the United States. (b) A fluid milk processor...

  12. 40 CFR 725.300 - Scope and purpose.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 31 2014-07-01 2014-07-01 false Scope and purpose. 725.300 Section 725.300 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT REPORTING REQUIREMENTS AND REVIEW PROCESSES FOR MICROORGANISMS Exemptions for Test Marketing § 725.300 Scope...

  13. 27 CFR 40.355 - Return of manufacturer.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ..., DEPARTMENT OF THE TREASURY (CONTINUED) TOBACCO MANUFACTURE OF TOBACCO PRODUCTS, CIGARETTE PAPERS AND TUBES, AND PROCESSED TOBACCO Manufacture of Cigarette Papers and Tubes Taxes § 40.355 Return of manufacturer. (a) Requirement for filing. A manufacturer of cigarette papers and tubes shall file, for each factory...

  14. 40 CFR 240.208-2 - Recommended procedures: Design.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ....208-2 Section 240.208-2 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures... allow for removal from the site of residue or other solids in a manner that protects the environment. ...

  15. 50 CFR 260.102 - Equipment.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 50 Wildlife and Fisheries 9 2011-10-01 2011-10-01 false Equipment. 260.102 Section 260.102... Products for Human Consumption Requirements for Plants Operating Under Continuous Inspection on A Contract Basis 1 § 260.102 Equipment. All equipment used for receiving, washing, segregating, picking, processing...

  16. 27 CFR 40.355 - Return of manufacturer.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ..., DEPARTMENT OF THE TREASURY (CONTINUED) TOBACCO MANUFACTURE OF TOBACCO PRODUCTS, CIGARETTE PAPERS AND TUBES, AND PROCESSED TOBACCO Manufacture of Cigarette Papers and Tubes Taxes § 40.355 Return of manufacturer. (a) Requirement for filing. A manufacturer of cigarette papers and tubes shall file, for each factory...

  17. 27 CFR 40.355 - Return of manufacturer.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ..., DEPARTMENT OF THE TREASURY (CONTINUED) TOBACCO MANUFACTURE OF TOBACCO PRODUCTS, CIGARETTE PAPERS AND TUBES, AND PROCESSED TOBACCO Manufacture of Cigarette Papers and Tubes Taxes § 40.355 Return of manufacturer. (a) Requirement for filing. A manufacturer of cigarette papers and tubes shall file, for each factory...

  18. 27 CFR 40.355 - Return of manufacturer.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ..., DEPARTMENT OF THE TREASURY (CONTINUED) TOBACCO MANUFACTURE OF TOBACCO PRODUCTS, CIGARETTE PAPERS AND TUBES, AND PROCESSED TOBACCO Manufacture of Cigarette Papers and Tubes Taxes § 40.355 Return of manufacturer. (a) Requirement for filing. A manufacturer of cigarette papers and tubes shall file, for each factory...

  19. 27 CFR 40.355 - Return of manufacturer.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ..., DEPARTMENT OF THE TREASURY (CONTINUED) TOBACCO MANUFACTURE OF TOBACCO PRODUCTS, CIGARETTE PAPERS AND TUBES, AND PROCESSED TOBACCO Manufacture of Cigarette Papers and Tubes Taxes § 40.355 Return of manufacturer. (a) Requirement for filing. A manufacturer of cigarette papers and tubes shall file, for each factory...

  20. 40 CFR 240.201 - Solid wastes excluded.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Solid wastes excluded. 240.201 Section 240.201 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.201 Solid...

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