Developing Elementary Math and Science Process Skills Through Engineering Design Instruction

NASA Astrophysics Data System (ADS)

Strong, Matthew G.

This paper examines how elementary students can develop math and science process skills through an engineering design approach to instruction. The performance and development of individual process skills overall and by gender were also examined. The study, preceded by a pilot, took place in a grade four extracurricular engineering design program in a public, suburban school district. Students worked in pairs and small groups to design and construct airplane models from styrofoam, paper clips, and toothpicks. The development and performance of process skills were assessed through a student survey of learning gains, an engineering design packet rubric (student work), observation field notes, and focus group notes. The results indicate that students can significantly develop process skills, that female students may develop process skills through engineering design better than male students, and that engineering design is most helpful for developing the measuring, suggesting improvements, and observing process skills. The study suggests that a more regular engineering design program or curriculum could be beneficial for students' math and science abilities both in this school and for the elementary field as a whole.

Process characterization and Design Space definition.

PubMed

Hakemeyer, Christian; McKnight, Nathan; St John, Rick; Meier, Steven; Trexler-Schmidt, Melody; Kelley, Brian; Zettl, Frank; Puskeiler, Robert; Kleinjans, Annika; Lim, Fred; Wurth, Christine

2016-09-01

Quality by design (QbD) is a global regulatory initiative with the goal of enhancing pharmaceutical development through the proactive design of pharmaceutical manufacturing process and controls to consistently deliver the intended performance of the product. The principles of pharmaceutical development relevant to QbD are described in the ICH guidance documents (ICHQ8-11). An integrated set of risk assessments and their related elements developed at Roche/Genentech were designed to provide an overview of product and process knowledge for the production of a recombinant monoclonal antibody (MAb). This chapter describes the tools used for the characterization and validation of MAb manufacturing process under the QbD paradigm. This comprises risk assessments for the identification of potential Critical Process Parameters (pCPPs), statistically designed experimental studies as well as studies assessing the linkage of the unit operations. Outcome of the studies is the classification of process parameters according to their criticality and the definition of appropriate acceptable ranges of operation. The process and product knowledge gained in these studies can lead to the approval of a Design Space. Additionally, the information gained in these studies are used to define the 'impact' which the manufacturing process can have on the variability of the CQAs, which is used to define the testing and monitoring strategy. Copyright © 2016 International Alliance for Biological Standardization. Published by Elsevier Ltd. All rights reserved.

Engineering design: A cognitive process approach

NASA Astrophysics Data System (ADS)

Strimel, Greg Joseph

The intent of this dissertation was to identify the cognitive processes used by advanced pre-engineering students to solve complex engineering design problems. Students in technology and engineering education classrooms are often taught to use an ideal engineering design process that has been generated mostly by educators and curriculum developers. However, the review of literature showed that it is unclear as to how advanced pre-engineering students cognitively navigate solving a complex and multifaceted problem from beginning to end. Additionally, it was unclear how a student thinks and acts throughout their design process and how this affects the viability of their solution. Therefore, Research Objective 1 was to identify the fundamental cognitive processes students use to design, construct, and evaluate operational solutions to engineering design problems. Research Objective 2 was to determine identifiers within student cognitive processes for monitoring aptitude to successfully design, construct, and evaluate technological solutions. Lastly, Research Objective 3 was to create a conceptual technological and engineering problem-solving model integrating student cognitive processes for the improved development of problem-solving abilities. The methodology of this study included multiple forms of data collection. The participants were first given a survey to determine their prior experience with engineering and to provide a description of the subjects being studied. The participants were then presented an engineering design challenge to solve individually. While they completed the challenge, the participants verbalized their thoughts using an established "think aloud" method. These verbalizations were captured along with participant observational recordings using point-of-view camera technology. Additionally, the participant design journals, design artifacts, solution effectiveness data, and teacher evaluations were collected for analysis to help achieve the research objectives of this study. Two independent coders then coded the video/audio recordings and the additional design data using Halfin's (1973) 17 mental processes for technological problem-solving. The results of this study indicated that the participants employed a wide array of mental processes when solving engineering design challenges. However, the findings provide a general analysis of the number of times participants employed each mental process, as well as the amount of time consumed employing the various mental processes through the different stages of the engineering design process. The results indicated many similarities between the students solving the problem, which may highlight voids in current technology and engineering education curricula. Additionally, the findings showed differences between the processes employed by participants that created the most successful solutions and the participants who developed the least effective solutions. Upon comparing and contrasting these processes, recommendations for instructional strategies to enhance a student's capability for solving engineering design problems were developed. The results also indicated that students, when left without teacher intervention, use a simplified and more natural process to solve design challenges than the 12-step engineering design process reported in much of the literature. Lastly, these data indicated that students followed two different approaches to solving the design problem. Some students employed a sequential and logical approach, while others employed a nebulous, solution centered trial-and-error approach to solving the problem. In this study the participants who were more sequential had better performing solutions. Examining these two approaches and the student cognition data enabled the researcher to generate a conceptual engineering design model for the improved teaching and development of engineering design problem solving.

Design and Construction Process of Two LEED Certified University Buildings: A Collective Case Study

ERIC Educational Resources Information Center

Rich, Kim

2011-01-01

This study was conducted at the early stages of integrating LEED into the design process in which a clearer understanding of what sustainable and ecological design was about became evident through the duration of designing and building of two academic buildings on a university campus. In this case study, due to utilizing a grounded theory…

Integrating ergonomics in design processes: a case study within an engineering consultancy firm.

PubMed

Sørensen, Lene Bjerg; Broberg, Ole

2012-01-01

This paper reports on a case study within an engineering consultancy firm, where engineering designers and ergonomists were working together on the design of a new hospital sterile processing plant. The objective of the paper is to gain a better understanding of the premises for integrating ergonomics into engineering design processes and how different factors either promote or limit the integration. Based on a grounded theory approach a model illustrating these factors is developed and different hypotheses about how these factors either promote and/or limit the integration of ergonomics into design processes is presented along with the model.

Comparative effectiveness of colony-stimulating factors in febrile neutropenia prophylaxis: how results are affected by research design.

PubMed

Henk, Henry J; Li, Xiaoyan; Becker, Laura K; Xu, Hairong; Gong, Qi; Deeter, Robert G; Barron, Richard L

2015-01-01

To examine the impact of research design on results in two published comparative effectiveness studies. Guidelines for comparative effectiveness research have recommended incorporating disease process in study design. Based on the recommendations, we develop a checklist of considerations and apply the checklist in review of two published studies on comparative effectiveness of colony-stimulating factors. Both studies used similar administrative claims data, but different methods, which resulted in directionally different estimates. Major design differences between the two studies include: whether the timing of intervention in disease process was identified and whether study cohort and outcome assessment period were defined based on this temporal relationship. Disease process and timing of intervention should be incorporated into the design of comparative effectiveness studies.

HYFIRE II: fusion/high-temperature electrolysis conceptual-design study. Annual report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fillo, J.A.

1983-08-01

As in the previous HYFIRE design study, the current study focuses on coupling a Tokamak fusion reactor with a high-temperature blanket to a High-Temperature Electrolyzer (HTE) process to produce hydrogen and oxygen. Scaling of the STARFIRE reactor to allow a blanket power to 6000 MW(th) is also assumed. The primary difference between the two studies is the maximum inlet steam temperature to the electrolyzer. This temperature is decreased from approx. 1300/sup 0/ to approx. 1150/sup 0/C, which is closer to the maximum projected temperature of the Westinghouse fuel cell design. The process flow conditions change but the basic design philosophymore » and approaches to process design remain the same as before. Westinghouse assisted in the study in the areas of systems design integration, plasma engineering, balance-of-plant design, and electrolyzer technology.« less

A Critical Review of Instructional Design Process of Distance Learning System

ERIC Educational Resources Information Center

Chaudry, Muhammad Ajmal; ur-Rahman, Fazal

2010-01-01

Instructional design refers to planning, development, delivery and evaluation of instructional system. It is an applied field of study aiming at the application of descriptive research outcomes in regular instructional settings. The present study was designed to critically review the process of instructional design at Allama Iqbal Open University…

Cost studies for commercial fuselage crown designs

NASA Technical Reports Server (NTRS)

Walker, T. H.; Smith, P. J.; Truslove, G.; Willden, K. S.; Metschan, S. L.; Pfahl, C. L.

1991-01-01

Studies were conducted to evaluate the cost and weight potential of advanced composite design concepts in the crown region of a commercial transport. Two designs from each of three design families were developed using an integrated design-build team. A range of design concepts and manufacturing processes were included to allow isolation and comparison of cost centers. Detailed manufacturing/assembly plans were developed as the basis for cost estimates. Each of the six designs was found to have advantages over the 1995 aluminum benchmark in cost and weight trade studies. Large quadrant panels and cobonded frames were found to save significant assembly labor costs. Comparisons of high- and intermediate-performance fiber systems were made for skin and stringer applications. Advanced tow placement was found to be an efficient process for skin lay up. Further analysis revealed attractive processes for stringers and frames. Optimized designs were informally developed for each design family, combining the most attractive concepts and processes within that family. A single optimized design was selected as the most promising, and the potential for further optimization was estimated. Technical issues and barriers were identified.

An Investigation of the Artifacts and Process of Constructing Computers Games about Environmental Science in a Fifth Grade Classroom

ERIC Educational Resources Information Center

Baytak, Ahmet; Land, Susan M.

2011-01-01

This study employed a case study design (Yin, "Case study research, design and methods," 2009) to investigate the processes used by 5th graders to design and develop computer games within the context of their environmental science unit, using the theoretical framework of "constructionism." Ten fifth graders designed computer games using "Scratch"…

Information Design: A New Approach to Teaching Technical Writing Service Courses

ERIC Educational Resources Information Center

McKee, Candie DeLane

2012-01-01

This study used a needs assessment, process analysis, process design, and textbook design to develop a new process and new textbook, based on Cargile-Cook's layered literacies, Quesenbery's five qualities of usability, and Carliner's information design theories, for use in technical writing service learning courses. The needs assessment was based…

Design Process-System and Methodology of Design Research

NASA Astrophysics Data System (ADS)

Bashier, Fathi

2017-10-01

Studies have recognized the failure of the traditional design approach both in practice and in the studio. They showed that design problems today are too complex for the traditional approach to cope with and reflected a new interest in a better quality design services in order to meet the challenges of our time. In the mid-1970s and early 1980s, there has been a significant shift in focus within the field of design research towards the aim of creating a ‘design discipline’. The problem, as will be discussed, is the lack of an integrated theory of design knowledge that can explicitly describe the design process in a coherent way. As a consequence, the traditional approach fails to operate systematically, in a disciplinary manner. Addressing this problem is the primary goal of the research study in the design process currently being conducted in the research-based master studio at Wollega University, Ethiopia. The research study seeks to make a contribution towards a disciplinary approach, through proper understanding the mechanism of knowledge development within design process systems. This is the task of the ‘theory of design knowledge’. In this article the research project is introduced, and a model of the design process-system is developed in the studio as a research plan and a tool of design research at the same time. Based on data drawn from students’ research projects, the theory of design knowledge is developed and empirically verified through the research project.

Glasses-type wearable computer displays: usability considerations examined with a 3D glasses case study.

PubMed

Chang, Joonho; Moon, Seung Ki; Jung, Kihyo; Kim, Wonmo; Parkinson, Matthew; Freivalds, Andris; Simpson, Timothy W; Baik, Seon Pill

2018-05-01

This study presents usability considerations and solutions for the design of glasses-type wearable computer displays and examines their effectiveness in a case study. Design countermeasures were investigated by a four-step design process: (1) preliminary design analysis; (2) design idea generation; (3) final design selection; and (4) virtual fitting trial. Three design interventions were devised from the design process: (1) weight balance to reduce pressure concentrated on the nose, (2) compliant temples to accommodate diverse head sizes and (3) a hanger mechanism to help spectacle users hang their wearable display on their eye glasses. To investigate their effectiveness, in the case study, the novel 3D glasses adopting the three interventions were compared with two existing 3D glasses in terms of neck muscle fatigue and subjective discomfort rating. While neck muscle fatigue was not significantly different among the three glasses (p = 0.467), the novel glasses had significantly smaller discomfort ratings (p = 0.009). Relevance to Industry: A four-step design process identified usability considerations and solutions for the design of glasses-type wearable computer displays. A novel 3D glasses was proposed through the process and its effectiveness was validated. The results identify design considerations and opportunities relevant to the emerging wearable display industry.

A Flexible Pilot-Scale Setup for Real-Time Studies in Process Systems Engineering

ERIC Educational Resources Information Center

Panjapornpon, Chanin; Fletcher, Nathan; Soroush, Masoud

2006-01-01

This manuscript describes a flexible, pilot-scale setup that can be used for training students and carrying out research in process systems engineering. The setup allows one to study a variety of process systems engineering concepts such as design feasibility, design flexibility, control configuration selection, parameter estimation, process and…

Rethinking Design Process: Using 3D Digital Models as an Interface in Collaborative Session

ERIC Educational Resources Information Center

Ding, Suining

2008-01-01

This paper describes a pilot study for an alternative design process by integrating a designer-user collaborative session with digital models. The collaborative session took place in a 3D AutoCAD class for a real world project. The 3D models served as an interface for designer-user collaboration during the design process. Students not only learned…

High School Engineering and Technology Education Integration through Design Challenges

ERIC Educational Resources Information Center

Mentzer, Nathan

2011-01-01

This study contextualized the use of the engineering design process by providing descriptions of how each element in a design process was integrated in an eleventh grade industry and engineering systems course. The guiding research question for this inquiry was: How do students engage in the engineering design process in a course where technology…

Experimental design methods for bioengineering applications.

PubMed

Keskin Gündoğdu, Tuğba; Deniz, İrem; Çalışkan, Gülizar; Şahin, Erdem Sefa; Azbar, Nuri

2016-01-01

Experimental design is a form of process analysis in which certain factors are selected to obtain the desired responses of interest. It may also be used for the determination of the effects of various independent factors on a dependent factor. The bioengineering discipline includes many different areas of scientific interest, and each study area is affected and governed by many different factors. Briefly analyzing the important factors and selecting an experimental design for optimization are very effective tools for the design of any bioprocess under question. This review summarizes experimental design methods that can be used to investigate various factors relating to bioengineering processes. The experimental methods generally used in bioengineering are as follows: full factorial design, fractional factorial design, Plackett-Burman design, Taguchi design, Box-Behnken design and central composite design. These design methods are briefly introduced, and then the application of these design methods to study different bioengineering processes is analyzed.

Feasibility study of an Integrated Program for Aerospace vehicle Design (IPAD). Volume 1A: Summary

NASA Technical Reports Server (NTRS)

Miller, R. E., Jr.; Redhed, D. D.; Kawaguchi, A. S.; Hansen, S. D.; Southall, J. W.

1973-01-01

IPAD was defined as a total system oriented to the product design process. This total system was designed to recognize the product design process, individuals and their design process tasks, and the computer-based IPAD System to aid product design. Principal elements of the IPAD System include the host computer and its interactive system software, new executive and data management software, and an open-ended IPAD library of technical programs to match the intended product design process. The basic goal of the IPAD total system is to increase the productivity of the product design organization. Increases in individual productivity were feasible through automation and computer support of routine information handling. Such proven automation can directly decrease cost and flowtime in the product design process.

Conceptualizing and Estimating Process Speed in Studies Employing Ecological Momentary Assessment Designs: A Multilevel Variance Decomposition Approach

ERIC Educational Resources Information Center

Shiyko, Mariya P.; Ram, Nilam

2011-01-01

Researchers have been making use of ecological momentary assessment (EMA) and other study designs that sample feelings and behaviors in real time and in naturalistic settings to study temporal dynamics and contextual factors of a wide variety of psychological, physiological, and behavioral processes. As EMA designs become more widespread,…

The NASA Exploration Design Team; Blueprint for a New Design Paradigm

NASA Technical Reports Server (NTRS)

Oberto, Robert E.; Nilsen, Erik; Cohen, Ron; Wheeler, Rebecca; DeFlorio, Paul

2005-01-01

NASA has chosen JPL to deliver a NASA-wide rapid-response real-time collaborative design team to perform rapid execution of program, system, mission, and technology trade studies. This team will draw on the expertise of all NASA centers and external partners necessary. The NASA Exploration Design Team (NEDT) will be led by NASA Headquarters, with field centers and partners added according to the needs of each study. Through real-time distributed collaboration we will effectively bring all NASA field centers directly inside Headquarters. JPL's Team X pioneered the technique of real time collaborative design 8 years ago. Since its inception, Team X has performed over 600 mission studies and has reduced per-study cost by a factor of 5 and per-study duration by a factor of 10 compared to conventional design processes. The Team X concept has spread to other NASA centers, industry, academia, and international partners. In this paper, we discuss the extension of the JPL Team X process to the NASA-wide collaborative design team. We discuss the architecture for such a process and elaborate on the implementation challenges of this process. We further discuss our current ideas on how to address these challenges.

On-Line Critiques in Collaborative Design Studio

ERIC Educational Resources Information Center

Sagun, Aysu; Demirkan, Halime

2009-01-01

In this study, the Design Collaboration Model (DCM) was developed to provide a medium for the on-line collaboration of the design courses. The model was based on the situated and reflective practice characteristics of the design process. The segmentation method was used to analyse the design process observed both in the design diaries and the…

Practicing universal design to actual hand tool design process.

PubMed

Lin, Kai-Chieh; Wu, Chih-Fu

2015-09-01

UD evaluation principles are difficult to implement in product design. This study proposes a methodology for implementing UD in the design process through user participation. The original UD principles and user experience are used to develop the evaluation items. Difference of product types was considered. Factor analysis and Quantification theory type I were used to eliminate considered inappropriate evaluation items and to examine the relationship between evaluation items and product design factors. Product design specifications were established for verification. The results showed that converting user evaluation into crucial design verification factors by the generalized evaluation scale based on product attributes as well as the design factors applications in product design can improve users' UD evaluation. The design process of this study is expected to contribute to user-centered UD application. Copyright © 2015 Elsevier Ltd and The Ergonomics Society. All rights reserved.

Analyzing Team Based Engineering Design Process in Computer Supported Collaborative Learning

ERIC Educational Resources Information Center

Lee, Dong-Kuk; Lee, Eun-Sang

2016-01-01

The engineering design process has been largely implemented in a collaborative project format. Recently, technological advancement has helped collaborative problem solving processes such as engineering design to have efficient implementation using computers or online technology. In this study, we investigated college students' interaction and…

Shape design of an optimal comfortable pillow based on the analytic hierarchy process method

PubMed Central

Liu, Shuo-Fang; Lee, Yann-Long; Liang, Jung-Chin

2011-01-01

Objective Few studies have analyzed the shapes of pillows. The purpose of this study was to investigate the relationship between the pillow shape design and subjective comfort level for asymptomatic subjects. Methods Four basic pillow designs factors were selected on the basis of literature review and recombined into 8 configurations for testing the rank of degrees of comfort. The data were analyzed by the analytic hierarchy process method to determine the most comfortable pillow. Results Pillow number 4 was the most comfortable pillow in terms of head, neck, shoulder, height, and overall comfort. The design factors of pillow number 4 were using a combination of standard, cervical, and shoulder pillows. A prototype of this pillow was developed on the basis of the study results for designing future pillow shapes. Conclusions This study investigated the comfort level of particular users and redesign features of a pillow. A deconstruction analysis would simplify the process of determining the most comfortable pillow design and aid designers in designing pillows for groups. PMID:22654680

A quality by design approach to understand formulation and process variability in pharmaceutical melt extrusion processes.

PubMed

Patwardhan, Ketaki; Asgarzadeh, Firouz; Dassinger, Thomas; Albers, Jessica; Repka, Michael A

2015-05-01

In this study, the principles of quality by design (QbD) have been uniquely applied to a pharmaceutical melt extrusion process for an immediate release formulation with a low melting model drug, ibuprofen. Two qualitative risk assessment tools - Fishbone diagram and failure mode effect analysis - were utilized to strategically narrow down the most influential parameters. Selected variables were further assessed using a Plackett-Burman screening study, which was upgraded to a response surface design consisting of the critical factors to study the interactions between the study variables. In process torque, glass transition temperature (Tg ) of the extrudates, assay, dissolution and phase change were measured as responses to evaluate the critical quality attributes (CQAs) of the extrudates. The effect of each study variable on the measured responses was analysed using multiple regression for the screening design and partial least squares for the optimization design. Experimental limits for formulation and process parameters to attain optimum processing have been outlined. A design space plot describing the domain of experimental variables within which the CQAs remained unchanged was developed. A comprehensive approach for melt extrusion product development based on the QbD methodology has been demonstrated. Drug loading concentrations between 40- 48%w/w and extrusion temperature in the range of 90-130°C were found to be the most optimum. © 2015 Royal Pharmaceutical Society.

Towards a systems approach to risk considerations for concurrent design

NASA Technical Reports Server (NTRS)

Meshkat, Leila; Oberto, Robert E.

2004-01-01

This paper describes the new process used by the Project Design Center at NASA's Jet Propulsion Laboratory for the identification, assessment and communication of risk elements throughout the lifecycle of a mission design. This process includes a software tool, 'RAP' that collects and communicates risk information between the various designers and a 'risk expert' who mediates this process. The establishment of this process is an attempt towards the systematic consideration of risk in the design decision making process. Using this process, we are able to better keep track of the risks associated with the design decisions. Furthermore, it helps us develop better risk profiles for the studies under consideration. We aim to refine and expand the current process to enable more thorough risk analysis capabilities in the future.

Application of Quality by Design to the characterization of the cell culture process of an Fc-Fusion protein.

PubMed

Rouiller, Yolande; Solacroup, Thomas; Deparis, Véronique; Barbafieri, Marco; Gleixner, Ralf; Broly, Hervé; Eon-Duval, Alex

2012-06-01

The production bioreactor step of an Fc-Fusion protein manufacturing cell culture process was characterized following Quality by Design principles. Using scientific knowledge derived from the literature and process knowledge gathered during development studies and manufacturing to support clinical trials, potential critical and key process parameters with a possible impact on product quality and process performance, respectively, were determined during a risk assessment exercise. The identified process parameters were evaluated using a design of experiment approach. The regression models generated from the data allowed characterizing the impact of the identified process parameters on quality attributes. The main parameters having an impact on product titer were pH and dissolved oxygen, while those having the highest impact on process- and product-related impurities and variants were pH and culture duration. The models derived from characterization studies were used to define the cell culture process design space. The design space limits were set in such a way as to ensure that the drug substance material would consistently have the desired quality. Copyright © 2012 Elsevier B.V. All rights reserved.

User roles and contributions during the new product development process in collaborative innovation communities.

PubMed

Guo, Wei; Zheng, Qing; An, Weijin; Peng, Wei

2017-09-01

Collaborative innovation (co-innovation) community emerges as a new product design platform where companies involve users in the new product development (NPD) process. Large numbers of users participate and contribute to the process voluntarily. This exploratory study investigates the heterogeneous roles of users based on a global co-innovation project in online community. Content analysis, social network analysis and cluster method are employed to measure user behaviors, distinguish user roles, and analyze user contributions. The study identifies six user roles that emerge during the NPD process in co-innovation community: project leader, active designer, generalist, communicator, passive designer, and observer. The six user roles differ in their contribution forms and quality. This paper contributes to research on co-innovation in online communities, including design team structure, user roles and their contribution to design task and solution, as well as user value along the process. In addition, the study provides practices guidance on implementing project, attracting users, and designing platform for co-innovation community practitioners. Copyright © 2017 Elsevier Ltd. All rights reserved.

Using system dynamics for collaborative design: a case study

PubMed Central

Elf, Marie; Putilova, Mariya; von Koch, Lena; Öhrn, Kerstin

2007-01-01

Background In order to facilitate the collaborative design, system dynamics (SD) with a group modelling approach was used in the early stages of planning a new stroke unit. During six workshops a SD model was created in a multiprofessional group. Aim To explore to which extent and how the use of system dynamics contributed to the collaborative design process. Method A case study was conducted using several data sources. Results SD supported a collaborative design, by facilitating an explicit description of stroke care process, a dialogue and a joint understanding. The construction of the model obliged the group to conceptualise the stroke care and experimentation with the model gave the opportunity to reflect on care. Conclusion SD facilitated the collaborative design process and should be integrated in the early stages of the design process as a quality improvement tool. PMID:17683519

Application of the quality by design approach to the drug substance manufacturing process of an Fc fusion protein: towards a global multi-step design space.

PubMed

Eon-duval, Alex; Valax, Pascal; Solacroup, Thomas; Broly, Hervé; Gleixner, Ralf; Strat, Claire L E; Sutter, James

2012-10-01

The article describes how Quality by Design principles can be applied to the drug substance manufacturing process of an Fc fusion protein. First, the quality attributes of the product were evaluated for their potential impact on safety and efficacy using risk management tools. Similarly, process parameters that have a potential impact on critical quality attributes (CQAs) were also identified through a risk assessment. Critical process parameters were then evaluated for their impact on CQAs, individually and in interaction with each other, using multivariate design of experiment techniques during the process characterisation phase. The global multi-step Design Space, defining operational limits for the entire drug substance manufacturing process so as to ensure that the drug substance quality targets are met, was devised using predictive statistical models developed during the characterisation study. The validity of the global multi-step Design Space was then confirmed by performing the entire process, from cell bank thawing to final drug substance, at its limits during the robustness study: the quality of the final drug substance produced under different conditions was verified against predefined targets. An adaptive strategy was devised whereby the Design Space can be adjusted to the quality of the input material to ensure reliable drug substance quality. Finally, all the data obtained during the process described above, together with data generated during additional validation studies as well as manufacturing data, were used to define the control strategy for the drug substance manufacturing process using a risk assessment methodology. Copyright © 2012 Wiley-Liss, Inc.

Development of a Premium Quality Plasma-derived IVIg (IQYMUNE®) Utilizing the Principles of Quality by Design-A Worked-through Case Study.

PubMed

Paolantonacci, Philippe; Appourchaux, Philippe; Claudel, Béatrice; Ollivier, Monique; Dennett, Richard; Siret, Laurent

2018-01-01

Polyvalent human normal immunoglobulins for intravenous use (IVIg), indicated for rare and often severe diseases, are complex plasma-derived protein preparations. A quality by design approach has been used to develop the Laboratoire Français du Fractionnement et des Biotechnologies new-generation IVIg, targeting a high level of purity to generate an enhanced safety profile while maintaining a high level of efficacy. A modular approach of quality by design was implemented consisting of five consecutive steps to cover all the stages from the product design to the final product control strategy.A well-defined target product profile was translated into 27 product quality attributes that formed the basis of the process design. In parallel, a product risk analysis was conducted and identified 19 critical quality attributes among the product quality attributes. Process risk analysis was carried out to establish the links between process parameters and critical quality attributes. Twelve critical steps were identified, and for each of these steps a risk mitigation plan was established.Among the different process risk mitigation exercises, five process robustness studies were conducted at qualified small scale with a design of experiment approach. For each process step, critical process parameters were identified and, for each critical process parameter, proven acceptable ranges were established. The quality risk management and risk mitigation outputs, including verification of proven acceptable ranges, were used to design the process verification exercise at industrial scale.Finally, the control strategy was established using a mix, or hybrid, of the traditional approach plus elements of the quality by design enhanced approach, as illustrated, to more robustly assign material and process controls and in order to securely meet product specifications.The advantages of this quality by design approach were improved process knowledge for industrial design and process validation and a clear justification of the process and product specifications as a basis for control strategy and future comparability exercises. © PDA, Inc. 2018.

Study unique artistic lopburi province for design brass tea set of bantahkrayang community

NASA Astrophysics Data System (ADS)

Pliansiri, V.; Seviset, S.

2017-07-01

The objectives of this study were as follows: 1) to study the production process of handcrafted Brass Tea Set; and 2) to design and develop the handcrafted of Brass Tea Set. The process of design was started by mutual analytical processes and conceptual framework for product design, Quality Function Deployment, Theory of Inventive Problem Solving, Principles of Craft Design, and Principle of Reverse Engineering. The experts in field of both Industrial Product Design and Brass Handicraft Product, have evaluated the Brass Tea Set design and created prototype of Brass tea set by the sample of consumers who have ever bought the Brass Tea Set of Bantahkrayang Community on this research. The statistics methods used were percentage, mean ({{{\\overline X}} = }) and standard deviation (S.D.) 3. To assess consumer satisfaction toward of handcrafted Brass tea set was at the high level.

A Co-Design Process Microanalysis: Stages and Facilitators of an Inquiry-Based and Technology-Enhanced Learning Scenario

ERIC Educational Resources Information Center

Barbera, Elena; Garcia, Iolanda; Fuertes-Alpiste, Marc

2017-01-01

This paper presents a case study of the co-design process for an online course on Sustainable Development (Degree in Tourism) involving the teacher, two students, and the project researchers. The co-design process was founded on an inquiry-based and technology-enhanced model that takes shape in a set of design principles. The research had two main…

Affordable Design: A Methodolgy to Implement Process-Based Manufacturing Cost into the Traditional Performance-Focused Multidisciplinary Design Optimization

NASA Technical Reports Server (NTRS)

Bao, Han P.; Samareh, J. A.

2000-01-01

The primary objective of this paper is to demonstrate the use of process-based manufacturing and assembly cost models in a traditional performance-focused multidisciplinary design and optimization process. The use of automated cost-performance analysis is an enabling technology that could bring realistic processbased manufacturing and assembly cost into multidisciplinary design and optimization. In this paper, we present a new methodology for incorporating process costing into a standard multidisciplinary design optimization process. Material, manufacturing processes, and assembly processes costs then could be used as the objective function for the optimization method. A case study involving forty-six different configurations of a simple wing is presented, indicating that a design based on performance criteria alone may not necessarily be the most affordable as far as manufacturing and assembly cost is concerned.

Case study: Lockheed-Georgia Company integrated design process

NASA Technical Reports Server (NTRS)

Waldrop, C. T.

1980-01-01

A case study of the development of an Integrated Design Process is presented. The approach taken in preparing for the development of an integrated design process includes some of the IPAD approaches such as developing a Design Process Model, cataloging Technical Program Elements (TPE's), and examining data characteristics and interfaces between contiguous TPE's. The implementation plan is based on an incremental development of capabilities over a period of time with each step directed toward, and consistent with, the final architecture of a total integrated system. Because of time schedules and different computer hardware, this system will not be the same as the final IPAD release; however, many IPAD concepts will no doubt prove applicable as the best approach. Full advantage will be taken of the IPAD development experience. A scenario that could be typical for many companies, even outside the aerospace industry, in developing an integrated design process for an IPAD-type environment is represented.

Statistical optimization of process parameters for lipase-catalyzed synthesis of triethanolamine-based esterquats using response surface methodology in 2-liter bioreactor.

PubMed

Masoumi, Hamid Reza Fard; Basri, Mahiran; Kassim, Anuar; Abdullah, Dzulkefly Kuang; Abdollahi, Yadollah; Abd Gani, Siti Salwa; Rezaee, Malahat

2013-01-01

Lipase-catalyzed production of triethanolamine-based esterquat by esterification of oleic acid (OA) with triethanolamine (TEA) in n-hexane was performed in 2 L stirred-tank reactor. A set of experiments was designed by central composite design to process modeling and statistically evaluate the findings. Five independent process variables, including enzyme amount, reaction time, reaction temperature, substrates molar ratio of OA to TEA, and agitation speed, were studied under the given conditions designed by Design Expert software. Experimental data were examined for normality test before data processing stage and skewness and kurtosis indices were determined. The mathematical model developed was found to be adequate and statistically accurate to predict the optimum conversion of product. Response surface methodology with central composite design gave the best performance in this study, and the methodology as a whole has been proven to be adequate for the design and optimization of the enzymatic process.

Evaluating the Effects of Culvert Designs on Ecosystem Processes in Northern Wisconsin Streams

Treesearch

J. C. Olson; A. M. Marcarelli; A.L. Timm; S.L. Eggert; R.K. Kolka

2017-01-01

Culvert replacements are commonly undertaken to restore aquatic organism passage and stream hydrologic and geomorphic conditions, but their effects on ecosystem processes are rarely quantified. The objective of this study was to investigate the effects of two culvert replacement designs on stream ecosystem processes. The stream simulation design, where culverts...

Defining process design space for a hydrophobic interaction chromatography (HIC) purification step: application of quality by design (QbD) principles.

PubMed

Jiang, Canping; Flansburg, Lisa; Ghose, Sanchayita; Jorjorian, Paul; Shukla, Abhinav A

2010-12-15

The concept of design space has been taking root under the quality by design paradigm as a foundation of in-process control strategies for biopharmaceutical manufacturing processes. This paper outlines the development of a design space for a hydrophobic interaction chromatography (HIC) process step. The design space included the impact of raw material lot-to-lot variability and variations in the feed stream from cell culture. A failure modes and effects analysis was employed as the basis for the process characterization exercise. During mapping of the process design space, the multi-dimensional combination of operational variables were studied to quantify the impact on process performance in terms of yield and product quality. Variability in resin hydrophobicity was found to have a significant influence on step yield and high-molecular weight aggregate clearance through the HIC step. A robust operating window was identified for this process step that enabled a higher step yield while ensuring acceptable product quality. © 2010 Wiley Periodicals, Inc.

Design and information requirements for travel and tourism needs on scenic byways.

DOT National Transportation Integrated Search

1994-01-01

The purpose of this study was to develop a system design and information evaluation process that could be used to review proposed or designated scenic byways. The process was intended to ensure that the geometric and traffic design of these roads wer...

How does the context and design of participatory decision-making processes affect their outcomes? Evidence from sustainable land management in global drylands.

NASA Astrophysics Data System (ADS)

de Vente, Joris; Reed, Mark; Stringer, Lindsay; Valente, Sandra; Newig, Jens

2014-05-01

It is widely accepted that the design of participatory processes in environmental management needs to be adapted to local contexts. Yet, it is not clear which elements of process design are universal, making it difficult to design processes that deliver beneficial outcomes across different contexts. We used empirical evidence to analyse the extent to which context and process design can enable or impede stakeholder participation and facilitate beneficial environmental and social outcomes in a range of decision-making contexts where stakeholders are engaged in environmental management. To explore the role of national-scale context on the outcomes of participatory processes, we interviewed facilitators from a process that was replicated across 13 dryland study sites around the world, which focussed on selecting Sustainable Land Management (SLM) options in close collaboration with stakeholders. To explore the role of process design and local context, we interviewed participants and facilitators in 11 case studies in Spain and Portugal in which different process designs were used. Interview data were analysed using a combination of quantitative and qualitative approaches to characterise relationships between process design, context and process outcomes. The similarity of outcomes across the 13 international study sites suggested that the national socio-cultural context in which a participatory process is conducted has little impact on its outcomes. However, analysis of cases from Spain and Portugal showed that some aspects of local context may affect outcomes. Having said this, factors associated with process design and participant selection played a more significant role in influencing outcomes in both countries. Processes that led to more beneficial outcomes for the environment and/or participants were likely to include: the legitimate representation of stakeholders; professional facilitation including structured methods for eliciting and aggregating information and balancing power dynamics between participants; and the provision of information and decision-making power to all participants. Participatory processes initiated or facilitated by government bodies led to significantly less trust, information gain, learning, and flexible solutions. However, in these processes, decisions were more acceptable to and likely to be implemented by governments and by those who had to apply them on the ground. These findings provide a solid empirical basis for best practice in the design of participatory processes in SLM in a number of contexts internationally, which if followed, increase the likelihood of providing beneficial environmental and social outcomes for those involved.

Toward Eco Product Development with Qualitative and CAE Design Process - Case Study of Flame Guiding Module

NASA Astrophysics Data System (ADS)

Chen, W. L.; Chao, F. L.

2018-04-01

Sustainable products become increasingly important for company in addressing eco-performance to satisfy global environmental regulations. Case study of flame guiding module reviewed design process and concerns related to the torch design. For enhancing flame height, the torch was embedded with an airflow guidance structure. The design process and design methodologies were investigated as an eco-design case study. Combine qualitative and CAE simulation were proposed to fulfil its main and auxiliary functions including reduction of impact during use. The design guidelines help prevent mistake arrangements, CAE helps understand combustion phenomenon. The flow field simulation enables fine tune of geometric design. Functional test and measurement are carried out to confirm the product features. On Eco-performance, we choose 5 items for evaluation the status of previous and redesign module, namely function need, low impact material, few manufacturing steps, low energy consumption, and safety. The radar diagram indicates that eco-performance of redesign module is better. Life cycle assessment calculated the carbon footprint of the manufacturing and processing stage with Eco-it. By using recycled steel in the flame module, it reduces raw material stage carbon footprint significantly.

Using the cognitive interviewing process to improve survey design by allied health: A qualitative study.

PubMed

Howlett, Owen; McKinstry, Carol; Lannin, Natasha A

2018-04-01

Allied health professionals frequently use surveys to collect data for clinical practice and service improvement projects. Careful development and piloting of purpose-designed surveys is important to ensure intended measuring (that respondents correctly interpret survey items when responding). Cognitive interviewing is a specific technique that can improve the design of self-administered surveys. The aim of this study was to describe the use of the cognitive interviewing process to improve survey design, which involved a purpose-designed, online survey evaluating staff use of functional electrical stimulation. A qualitative study involving one round of cognitive interviewing with three occupational therapists and three physiotherapists. The cognitive interviewing process identified 11 issues with the draft survey, which could potentially influence the validity and quality of responses. The raised issues included difficulties with: processing the question to be able to respond, determining a response to the question, retrieving relevant information from memory and comprehending the written question. Twelve survey amendments were made following the cognitive interviewing process, comprising four additions, seven revisions and one correction. The cognitive interviewing process applied during the development of a purpose-designed survey enabled the identification of potential problems and informed revisions to the survey prior to its use. © 2017 Occupational Therapy Australia.

Toward Understanding the Cognitive Processes of Software Design in Novice Programmers

ERIC Educational Resources Information Center

Yeh, Kuo-Chuan

2009-01-01

This study provides insights with regard to the types of cognitive processes that are involved in the formation of mental models and the way those models change over the course of a semester in novice programmers doing a design task. Eight novice programmers participated in this study for three distinct software design sessions, using the same…

Optimal cure cycle design for autoclave processing of thick composites laminates: A feasibility study

NASA Technical Reports Server (NTRS)

Hou, Jean W.

1985-01-01

The thermal analysis and the calculation of thermal sensitivity of a cure cycle in autoclave processing of thick composite laminates were studied. A finite element program for the thermal analysis and design derivatives calculation for temperature distribution and the degree of cure was developed and verified. It was found that the direct differentiation was the best approach for the thermal design sensitivity analysis. In addition, the approach of the direct differentiation provided time histories of design derivatives which are of great value to the cure cycle designers. The approach of direct differentiation is to be used for further study, i.e., the optimal cycle design.

Sketching in Design Journals: An Analysis of Visual Representations in the Product Design Process

ERIC Educational Resources Information Center

Lau, Kimberly; Oehlberg, Lora; Agogino, Alice

2009-01-01

This paper explores the sketching behavior of designers and the role of sketching in the design process. Observations from a descriptive study of sketches provided in design journals, characterized by a protocol measuring sketching activities, are presented. A distinction is made between journals that are entirely tangible and those that contain…

The life cycles of six multi-center adaptive clinical trials focused on neurological emergencies developed for the Advancing Regulatory Science initiative of the National Institutes of Health and US Food and Drug Administration: Case studies from the Adaptive Designs Accelerating Promising Treatments Into Trials Project.

PubMed

Guetterman, Timothy C; Fetters, Michael D; Mawocha, Samkeliso; Legocki, Laurie J; Barsan, William G; Lewis, Roger J; Berry, Donald A; Meurer, William J

2017-01-01

Clinical trials are complicated, expensive, time-consuming, and frequently do not lead to discoveries that improve the health of patients with disease. Adaptive clinical trials have emerged as a methodology to provide more flexibility in design elements to better answer scientific questions regarding whether new treatments are efficacious. Limited observational data exist that describe the complex process of designing adaptive clinical trials. To address these issues, the Adaptive Designs Accelerating Promising Treatments Into Trials project developed six, tailored, flexible, adaptive, phase-III clinical trials for neurological emergencies, and investigators prospectively monitored and observed the processes. The objective of this work is to describe the adaptive design development process, the final design, and the current status of the adaptive trial designs that were developed. To observe and reflect upon the trial development process, we employed a rich, mixed methods evaluation that combined quantitative data from visual analog scale to assess attitudes about adaptive trials, along with in-depth qualitative data about the development process gathered from observations. The Adaptive Designs Accelerating Promising Treatments Into Trials team developed six adaptive clinical trial designs. Across the six designs, 53 attitude surveys were completed at baseline and after the trial planning process completed. Compared to baseline, the participants believed significantly more strongly that the adaptive designs would be accepted by National Institutes of Health review panels and non-researcher clinicians. In addition, after the trial planning process, the participants more strongly believed that the adaptive design would meet the scientific and medical goals of the studies. Introducing the adaptive design at early conceptualization proved critical to successful adoption and implementation of that trial. Involving key stakeholders from several scientific domains early in the process appears to be associated with improved attitudes towards adaptive designs over the life cycle of clinical trial development.

Natural gas operations: considerations on process transients, design, and control.

PubMed

Manenti, Flavio

2012-03-01

This manuscript highlights tangible benefits deriving from the dynamic simulation and control of operational transients of natural gas processing plants. Relevant improvements in safety, controllability, operability, and flexibility are obtained not only within the traditional applications, i.e. plant start-up and shutdown, but also in certain fields apparently time-independent such as the feasibility studies of gas processing plant layout and the process design of processes. Specifically, this paper enhances the myopic steady-state approach and its main shortcomings with respect to the more detailed studies that take into consideration the non-steady state behaviors. A portion of a gas processing facility is considered as case study. Process transients, design, and control solutions apparently more appealing from a steady-state approach are compared to the corresponding dynamic simulation solutions. Copyright © 2011 ISA. Published by Elsevier Ltd. All rights reserved.

A Systematic Approach of Employing Quality by Design Principles: Risk Assessment and Design of Experiments to Demonstrate Process Understanding and Identify the Critical Process Parameters for Coating of the Ethylcellulose Pseudolatex Dispersion Using Non-Conventional Fluid Bed Process.

PubMed

Kothari, Bhaveshkumar H; Fahmy, Raafat; Claycamp, H Gregg; Moore, Christine M V; Chatterjee, Sharmista; Hoag, Stephen W

2017-05-01

The goal of this study was to utilize risk assessment techniques and statistical design of experiments (DoE) to gain process understanding and to identify critical process parameters for the manufacture of controlled release multiparticulate beads using a novel disk-jet fluid bed technology. The material attributes and process parameters were systematically assessed using the Ishikawa fish bone diagram and failure mode and effect analysis (FMEA) risk assessment methods. The high risk attributes identified by the FMEA analysis were further explored using resolution V fractional factorial design. To gain an understanding of the processing parameters, a resolution V fractional factorial study was conducted. Using knowledge gained from the resolution V study, a resolution IV fractional factorial study was conducted; the purpose of this IV study was to identify the critical process parameters (CPP) that impact the critical quality attributes and understand the influence of these parameters on film formation. For both studies, the microclimate, atomization pressure, inlet air volume, product temperature (during spraying and curing), curing time, and percent solids in the coating solutions were studied. The responses evaluated were percent agglomeration, percent fines, percent yield, bead aspect ratio, median particle size diameter (d50), assay, and drug release rate. Pyrobuttons® were used to record real-time temperature and humidity changes in the fluid bed. The risk assessment methods and process analytical tools helped to understand the novel disk-jet technology and to systematically develop models of the coating process parameters like process efficiency and the extent of curing during the coating process.

Biomimetic design processes in architecture: morphogenetic and evolutionary computational design.

PubMed

Menges, Achim

2012-03-01

Design computation has profound impact on architectural design methods. This paper explains how computational design enables the development of biomimetic design processes specific to architecture, and how they need to be significantly different from established biomimetic processes in engineering disciplines. The paper first explains the fundamental difference between computer-aided and computational design in architecture, as the understanding of this distinction is of critical importance for the research presented. Thereafter, the conceptual relation and possible transfer of principles from natural morphogenesis to design computation are introduced and the related developments of generative, feature-based, constraint-based, process-based and feedback-based computational design methods are presented. This morphogenetic design research is then related to exploratory evolutionary computation, followed by the presentation of two case studies focusing on the exemplary development of spatial envelope morphologies and urban block morphologies.

Development of Crystallizer for Advanced Aqueous Reprocessing Process

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tadahiro Washiya; Atsuhiro Shibata; Toshiaki Kikuchi

2006-07-01

Crystallization is one of the remarkable technologies for future fuel reprocessing process that has safety and economical advantages. Japan Atomic Energy Agency (JAEA) (former Japan Nuclear Cycle Development Institute), Mitsubishi Material Corporation and Saitama University have been developing the crystallization process. In previous study, we carried out experimental studies with uranium, MOX and spent fuel conditions, and flowsheet analysis was considered. In association with these studies, an innovative continuous crystallizer and its system was developed to ensure high process performance. From the design study, an annular type continuous crystallizer was selected as the most promising design, and performance was confirmedmore » by small-scale test and engineering scale demonstration at uranium crystallization conditions. In this paper, the design study and the demonstration test results are described. (authors)« less

Demonstration of the feasibility of automated silicon solar cell fabrication

NASA Technical Reports Server (NTRS)

Taylor, W. E.; Schwartz, F. M.

1975-01-01

A study effort was undertaken to determine the process, steps and design requirements of an automated silicon solar cell production facility. Identification of the key process steps was made and a laboratory model was conceptually designed to demonstrate the feasibility of automating the silicon solar cell fabrication process. A detailed laboratory model was designed to demonstrate those functions most critical to the question of solar cell fabrication process automating feasibility. The study and conceptual design have established the technical feasibility of automating the solar cell manufacturing process to produce low cost solar cells with improved performance. Estimates predict an automated process throughput of 21,973 kilograms of silicon a year on a three shift 49-week basis, producing 4,747,000 hexagonal cells (38mm/side), a total of 3,373 kilowatts at an estimated manufacturing cost of $0.866 per cell or $1.22 per watt.

The Use of Executive Control Processes in Engineering Design by Engineering Students and Professional Engineers

ERIC Educational Resources Information Center

Dixon, Raymond A.; Johnson, Scott D.

2012-01-01

A cognitive construct that is important when solving engineering design problems is executive control process, or metacognition. It is a central feature of human consciousness that enables one "to be aware of, monitor, and control mental processes." The framework for this study was conceptualized by integrating the model for creative design, which…

Investigating a Method of Scaffolding Student-Designed Experiments

ERIC Educational Resources Information Center

Morgan, Kelly; Brooks, David W.

2012-01-01

The process of designing an experiment is a difficult one. Students often struggle to perform such tasks as the design process places a large cognitive load on students. Scaffolding is the process of providing support for a student to allow them to complete tasks they would otherwise not have been able to complete. This study sought to investigate…

Coal gasification systems engineering and analysis. Appendix B: Medium B+U gas design

NASA Technical Reports Server (NTRS)

1980-01-01

A four module, 20,000 TPD, based on KT coal gasification technology was designed. The plant processes Kentucky No. 9 coal with provisions for up to five percent North Alabama coal. Medium BTU gas with heat content of 305 BTU/SCF and not more than 200 ppm sulfur is the primary plant product. Sulfur is recovered for scale as prilled sulfur. Ash disposal is on site. The plant is designed for zero water discharge. Trade studies provided the basis for not using boiler produced steam to drive prime movers. Thus process derived steam in excess of process requirements in superheated for power use in prime movers. Electricity from the TVA grid is used to supply the balance of the plant prime mover power requirements. A study of the effect of mine mouth coal cleaning showed that coal cleaning is not an economically preferred route. The design procedure involved defining available processes to meet the requirements of each system, technical/economic trade studies to select the preferred processes, and engineering design and flow sheet development for each module. Cost studies assumed a staggered construction schedule for the four modules beginning spring 1981 and a 90% on stream factor.

RATES OF REACTION AND PROCESS DESIGN DATA FOR THE HYDROCARB PROCESS

EPA Science Inventory

The report provides experimental and process design data in support of studies for developing the coprocessing of fossil fuels with biomass by the Hydrocarb process. The experimental work includes the hydropyrolysis of biomass and the thermal decomposition of methane in a 2.44 m ...

The Study Review Process. WWC Process Brief

ERIC Educational Resources Information Center

What Works Clearinghouse, 2017

2017-01-01

Many studies of education interventions make claims about impacts on students' outcomes. Some studies have designs that enable readers to make causal inferences about the effects of an intervention but others have designs that do not permit these types of conclusions. To help policymakers, practitioners, and others make sense of study results, the…

Design for human factors (DfHF): a grounded theory for integrating human factors into production design processes.

PubMed

Village, Judy; Searcy, Cory; Salustri, Filipo; Patrick Neumann, W

2015-01-01

The 'design for human factors' grounded theory explains 'how' human factors (HF) went from a reactive, after-injury programme in safety, to being proactively integrated into each step of the production design process. In this longitudinal case study collaboration with engineers and HF Specialists in a large electronics manufacturer, qualitative data (e.g. meetings, interviews, observations and reflections) were analysed using a grounded theory methodology. The central tenet in the theory is that when HF Specialists acclimated to the engineering process, language and tools, and strategically aligned HF to the design and business goals of the organisation, HF became a means to improve business performance. This led to engineers 'pulling' HF Specialists onto their team. HF targets were adopted into engineering tools to communicate HF concerns quantitatively, drive continuous improvement, visibly demonstrate change and lead to benchmarking. Senior management held engineers accountable for HF as a key performance indicator, thus integrating HF into the production design process. Practitioner Summary: Research and practice lack explanations about how HF can be integrated early in design of production systems. This three-year case study and the theory derived demonstrate how ergonomists changed their focus to align with design and business goals to integrate HF into the design process.

The Influence of Game Design on the Collaborative Problem Solving Process: A Cross-Case Study of Multi-Player Collaborative Gameplay Analysis

ERIC Educational Resources Information Center

Yildirim, Nilay

2013-01-01

This cross-case study examines the relationships between game design attributes and collaborative problem solving process in the context of multi-player video games. The following game design attributes: sensory stimuli elements, level of challenge, and presentation of game goals and rules were examined to determine their influence on game…

Modeling and analysis of power processing systems: Feasibility investigation and formulation of a methodology

NASA Technical Reports Server (NTRS)

Biess, J. J.; Yu, Y.; Middlebrook, R. D.; Schoenfeld, A. D.

1974-01-01

A review is given of future power processing systems planned for the next 20 years, and the state-of-the-art of power processing design modeling and analysis techniques used to optimize power processing systems. A methodology of modeling and analysis of power processing equipment and systems has been formulated to fulfill future tradeoff studies and optimization requirements. Computer techniques were applied to simulate power processor performance and to optimize the design of power processing equipment. A program plan to systematically develop and apply the tools for power processing systems modeling and analysis is presented so that meaningful results can be obtained each year to aid the power processing system engineer and power processing equipment circuit designers in their conceptual and detail design and analysis tasks.

Media milling process optimization for manufacture of drug nanoparticles using design of experiments (DOE).

PubMed

Nekkanti, Vijaykumar; Marwah, Ashwani; Pillai, Raviraj

2015-01-01

Design of experiments (DOE), a component of Quality by Design (QbD), is systematic and simultaneous evaluation of process variables to develop a product with predetermined quality attributes. This article presents a case study to understand the effects of process variables in a bead milling process used for manufacture of drug nanoparticles. Experiments were designed and results were computed according to a 3-factor, 3-level face-centered central composite design (CCD). The factors investigated were motor speed, pump speed and bead volume. Responses analyzed for evaluating these effects and interactions were milling time, particle size and process yield. Process validation batches were executed using the optimum process conditions obtained from software Design-Expert® to evaluate both the repeatability and reproducibility of bead milling technique. Milling time was optimized to <5 h to obtain the desired particle size (d90 < 400 nm). The desirability function used to optimize the response variables and observed responses were in agreement with experimental values. These results demonstrated the reliability of selected model for manufacture of drug nanoparticles with predictable quality attributes. The optimization of bead milling process variables by applying DOE resulted in considerable decrease in milling time to achieve the desired particle size. The study indicates the applicability of DOE approach to optimize critical process parameters in the manufacture of drug nanoparticles.

Development of a Model for Measuring Scientific Processing Skills Based on Brain-Imaging Technology: Focused on the Experimental Design Process

ERIC Educational Resources Information Center

Lee, Il-Sun; Byeon, Jung-Ho; Kim, Young-shin; Kwon, Yong-Ju

2014-01-01

The purpose of this study was to develop a model for measuring experimental design ability based on functional magnetic resonance imaging (fMRI) during biological inquiry. More specifically, the researchers developed an experimental design task that measures experimental design ability. Using the developed experimental design task, they measured…

Reading Students' Minds: Design Assessment in Distance Education

ERIC Educational Resources Information Center

Jones, Derek

2014-01-01

This paper considers the design of assessment for students of design according to behaviourist versus experiential pedagogical approaches, relating these to output-oriented as opposed to process-oriented assessment methods. It is part case study and part recognition of the importance of process in design education and how this might be applied in…

User-Design: A Case Application in Health Care Training.

ERIC Educational Resources Information Center

Carr-Chellman, Alison; Cuyar, Craig; Breman, Jeroen

1998-01-01

Discussion of user-design as a theoretical process for creating training, software, and computer systems focuses on a case study that describes user-design methodology in home health care through the context of diffusing a new laptop patient-record-keeping system with home nurses. Research needs and implications for the design process are…

Quality by design case study: an integrated multivariate approach to drug product and process development.

PubMed

Huang, Jun; Kaul, Goldi; Cai, Chunsheng; Chatlapalli, Ramarao; Hernandez-Abad, Pedro; Ghosh, Krishnendu; Nagi, Arwinder

2009-12-01

To facilitate an in-depth process understanding, and offer opportunities for developing control strategies to ensure product quality, a combination of experimental design, optimization and multivariate techniques was integrated into the process development of a drug product. A process DOE was used to evaluate effects of the design factors on manufacturability and final product CQAs, and establish design space to ensure desired CQAs. Two types of analyses were performed to extract maximal information, DOE effect & response surface analysis and multivariate analysis (PCA and PLS). The DOE effect analysis was used to evaluate the interactions and effects of three design factors (water amount, wet massing time and lubrication time), on response variables (blend flow, compressibility and tablet dissolution). The design space was established by the combined use of DOE, optimization and multivariate analysis to ensure desired CQAs. Multivariate analysis of all variables from the DOE batches was conducted to study relationships between the variables and to evaluate the impact of material attributes/process parameters on manufacturability and final product CQAs. The integrated multivariate approach exemplifies application of QbD principles and tools to drug product and process development.

Active pharmaceutical ingredient (API) production involving continuous processes--a process system engineering (PSE)-assisted design framework.

PubMed

Cervera-Padrell, Albert E; Skovby, Tommy; Kiil, Søren; Gani, Rafiqul; Gernaey, Krist V

2012-10-01

A systematic framework is proposed for the design of continuous pharmaceutical manufacturing processes. Specifically, the design framework focuses on organic chemistry based, active pharmaceutical ingredient (API) synthetic processes, but could potentially be extended to biocatalytic and fermentation-based products. The method exploits the synergic combination of continuous flow technologies (e.g., microfluidic techniques) and process systems engineering (PSE) methods and tools for faster process design and increased process understanding throughout the whole drug product and process development cycle. The design framework structures the many different and challenging design problems (e.g., solvent selection, reactor design, and design of separation and purification operations), driving the user from the initial drug discovery steps--where process knowledge is very limited--toward the detailed design and analysis. Examples from the literature of PSE methods and tools applied to pharmaceutical process design and novel pharmaceutical production technologies are provided along the text, assisting in the accumulation and interpretation of process knowledge. Different criteria are suggested for the selection of batch and continuous processes so that the whole design results in low capital and operational costs as well as low environmental footprint. The design framework has been applied to the retrofit of an existing batch-wise process used by H. Lundbeck A/S to produce an API: zuclopenthixol. Some of its batch operations were successfully converted into continuous mode, obtaining higher yields that allowed a significant simplification of the whole process. The material and environmental footprint of the process--evaluated through the process mass intensity index, that is, kg of material used per kg of product--was reduced to half of its initial value, with potential for further reduction. The case-study includes reaction steps typically used by the pharmaceutical industry featuring different characteristic reaction times, as well as L-L separation and distillation-based solvent exchange steps, and thus constitutes a good example of how the design framework can be useful to efficiently design novel or already existing API manufacturing processes taking advantage of continuous processes. Copyright © 2012 Elsevier B.V. All rights reserved.

Selection process for trade study: Reusable Hydrogen Composite Tank System (RHCTS)

NASA Astrophysics Data System (ADS)

Greenberg, H. S.

1994-09-01

This document describes the selection process that will be used to identify the most suitable structural configuration option for an SSTO winged vehicle capable of delivering 25,000 lbs to a 220 nm circular orbit at 51.6 degree inclination. The most suitable RHCTS is within this configuration and will be the prototype design for subsequent design and analysis and the basis for the design and fabrication of a scale test article to be subjected to life cycle testing. The selection process for this TA 1 trade study is the same as that for the TA 2 trade study. As the trade study progresses additional insight may result in modifications to the selection criteria within in this process. Such modifications will result in an update of this document as appropriate.

Adapting Nielsen’s Design Heuristics to Dual Processing for Clinical Decision Support

PubMed Central

Taft, Teresa; Staes, Catherine; Slager, Stacey; Weir, Charlene

2016-01-01

The study objective was to improve the applicability of Nielson’s standard design heuristics for evaluating electronic health record (EHR) alerts and linked ordering support by integrating them with Dual Process theory. Through initial heuristic evaluation and a user study of 7 physicians, usability problems were identified. Through independent mapping of specific usability criteria to support for each of the Dual Cognitive processes (S1 and S2) and deliberation, agreement was reached on mapping criteria. Finally, usability errors from the heuristic and user study were mapped to S1 and S2. Adding a dual process perspective to specific heuristic analysis increases the applicability and relevance of computerized health information design evaluations. This mapping enables designers to measure that their systems are tailored to support attention allocation. System 1 will be supported by improving pattern recognition and saliency, and system 2 through efficiency and control of information access. PMID:28269915

Adapting Nielsen's Design Heuristics to Dual Processing for Clinical Decision Support.

PubMed

Taft, Teresa; Staes, Catherine; Slager, Stacey; Weir, Charlene

2016-01-01

The study objective was to improve the applicability of Nielson's standard design heuristics for evaluating electronic health record (EHR) alerts and linked ordering support by integrating them with Dual Process theory. Through initial heuristic evaluation and a user study of 7 physicians, usability problems were identified. Through independent mapping of specific usability criteria to support for each of the Dual Cognitive processes (S1 and S2) and deliberation, agreement was reached on mapping criteria. Finally, usability errors from the heuristic and user study were mapped to S1 and S2. Adding a dual process perspective to specific heuristic analysis increases the applicability and relevance of computerized health information design evaluations. This mapping enables designers to measure that their systems are tailored to support attention allocation. System 1 will be supported by improving pattern recognition and saliency, and system 2 through efficiency and control of information access.

A Web Centric Architecture for Deploying Multi-Disciplinary Engineering Design Processes

NASA Technical Reports Server (NTRS)

Woyak, Scott; Kim, Hongman; Mullins, James; Sobieszczanski-Sobieski, Jaroslaw

2004-01-01

There are continuous needs for engineering organizations to improve their design process. Current state of the art techniques use computational simulations to predict design performance, and optimize it through advanced design methods. These tools have been used mostly by individual engineers. This paper presents an architecture for achieving results at an organization level beyond individual level. The next set of gains in process improvement will come from improving the effective use of computers and software within a whole organization, not just for an individual. The architecture takes advantage of state of the art capabilities to produce a Web based system to carry engineering design into the future. To illustrate deployment of the architecture, a case study for implementing advanced multidisciplinary design optimization processes such as Bi-Level Integrated System Synthesis is discussed. Another example for rolling-out a design process for Design for Six Sigma is also described. Each example explains how an organization can effectively infuse engineering practice with new design methods and retain the knowledge over time.

Study of the 5E Instructional Model to Improve the Instructional Design Process of Novice Teachers

ERIC Educational Resources Information Center

Hu, Jiuhua; Gao, Chong; Liu, Yang

2017-01-01

This study investigated the effects of 5E instructional model on the teaching processes of novice teachers. First, we conducted a teaching design training project based on the 5E model for 40 novice teachers, and compared pre-texts of the teachers' teaching process from before the training with post-texts obtained immediately following the…

Process wastewater treatability study for Westinghouse fluidized-bed coal gasification

DOE Office of Scientific and Technical Information (OSTI.GOV)

Winton, S.L.; Buvinger, B.J.; Evans, J.M.

1983-11-01

In the development of a synthetic fuels facility, water usage and wastewater treatment are major areas of concern. Coal gasification processes generally produce relatively large volumes of gas condensates. These wastewaters are typically composed of a variety of suspended and dissolved organic and inorganic solids and dissolved gaseous contaminants. Fluidized-bed coal gasification (FBG) processes are no exception to this rule. The Department of Energy's Morgantown Energy Technology Center (METC), the Gas Research Institute (GRI), and the Environmental Protection Agency (EPA/IERLRTP) recognized the need for a FBG treatment program to provide process design data for FBG wastewaters during the environmental, health,more » and safety characterization of the Westinghouse Process Development Unit (PDU). In response to this need, METC developed conceptual designs and a program plan to obtain process design and performance data for treating wastewater from commercial-scale Westinghouse-based synfuels plants. As a result of this plan, METC, GRI, and EPA entered into a joint program to develop performance data, design parameters, conceptual designs, and cost estimates for treating wastewaters from a FBG plant. Wastewater from the Westinghouse PDU consists of process quench and gas cooling condensates which are similar to those produced by other FBG processes such as U-Gas, and entrained-bed gasification processes such as Texaco. Therefore, wastewater from this facility was selected as the basis for this study. This paper outlines the current program for developing process design and cost data for the treatment of these wastewaters.« less

Beyond access: a case study on the intersection between accessibility, sustainability, and universal design.

PubMed

Gossett, Andrea; Mirza, Mansha; Barnds, Ann Kathleen; Feidt, Daisy

2009-11-01

A growing emphasis has been placed on providing equal opportunities for all people, particularly people with disabilities, to support participation. Barriers to participation are represented in part by physical space restrictions. This article explores the decision-making process during the construction of a new office building housing a disability-rights organization. The building project featured in this study was developed on the principles of universal design, maximal accessibility, and sustainability to support access and participation. A qualitative case study approach was used involving collection of data through in-depth interviews with key decision-makers; non-participant observations at design meetings; and on-site tours. Qualitative thematic analysis along with the development of a classification system was used to understand specific building elements and the relevant decision processes from which they resulted. Recording and analyzing the design process revealed several key issues including grassroots involvement of stakeholders; interaction between universal design and sustainable design; addressing diversity through flexibility and universality; and segregationist accessibility versus universal design. This case study revealed complex interactions between accessibility, universal design, and sustainability. Two visual models were proposed to understand and analyze these complexities.

An Expert Teacher's Thinking and Teaching and Instructional Design Models and Principles: An Ethnographic Study.

ERIC Educational Resources Information Center

Moallem, Mahnaz

1998-01-01

Examines an expert teacher's thinking and teaching processes in order to link them to instructional-design procedures. Findings suggest that there were fundamental differences between the teacher's thinking and teaching processes and microinstructional design models. (Author/AEF)

Learning on the Fly: Exploring the Informal Learning Process of Aviation Instructors

ERIC Educational Resources Information Center

Wofford, Michael Grant; Ellinger, Andrea D.; Watkins, Karen E.

2013-01-01

Purpose: This study aims to examine the process of informal learning of aviation instructors. Design/methodology/approach: A qualitative instrumental case study design was used for this study. In-depth, multiple semi-structured interviews and document review were the primary approaches to data collection and the data were analyzed using constant…

Team Learning: Collective Reflection Processes in Teacher Teams

ERIC Educational Resources Information Center

Ohlsson, Jon

2013-01-01

Purpose: The purpose of this paper is to contribute to further studies of theoretical and conceptual understanding of teachers' team learning processes, with a main focus on team work, team atmosphere, and collective reflections. Design/methodology/approach: The empirical study was designed as a multi-case study in a research and development…

The Ontology of Clinical Research (OCRe): An Informatics Foundation for the Science of Clinical Research

PubMed Central

Sim, Ida; Tu, Samson W.; Carini, Simona; Lehmann, Harold P.; Pollock, Brad H.; Peleg, Mor; Wittkowski, Knut M.

2013-01-01

To date, the scientific process for generating, interpreting, and applying knowledge has received less informatics attention than operational processes for conducting clinical studies. The activities of these scientific processes — the science of clinical research — are centered on the study protocol, which is the abstract representation of the scientific design of a clinical study. The Ontology of Clinical Research (OCRe) is an OWL 2 model of the entities and relationships of study design protocols for the purpose of computationally supporting the design and analysis of human studies. OCRe’s modeling is independent of any specific study design or clinical domain. It includes a study design typology and a specialized module called ERGO Annotation for capturing the meaning of eligibility criteria. In this paper, we describe the key informatics use cases of each phase of a study’s scientific lifecycle, present OCRe and the principles behind its modeling, and describe applications of OCRe and associated technologies to a range of clinical research use cases. OCRe captures the central semantics that underlies the scientific processes of clinical research and can serve as an informatics foundation for supporting the entire range of knowledge activities that constitute the science of clinical research. PMID:24239612

Developing Engineering and Science Process Skills Using Design Software in an Elementary Education

NASA Astrophysics Data System (ADS)

Fusco, Christopher

This paper examines the development of process skills through an engineering design approach to instruction in an elementary lesson that combines Science, Technology, Engineering, and Math (STEM). The study took place with 25 fifth graders in a public, suburban school district. Students worked in groups of five to design and construct model bridges based on research involving bridge building design software. The assessment was framed around individual student success as well as overall group processing skills. These skills were assessed through an engineering design packet rubric (student work), student surveys of learning gains, observation field notes, and pre- and post-assessment data. The results indicate that students can successfully utilize design software to inform constructions of model bridges, develop science process skills through problem based learning, and understand academic concepts through a design project. The final result of this study shows that design engineering is effective for developing cooperative learning skills. The study suggests that an engineering program offered as an elective or as part of the mandatory curriculum could be beneficial for developing students' critical thinking, inter- and intra-personal skills, along with an increased their understanding and awareness for scientific phenomena. In conclusion, combining a design approach to instruction with STEM can increase efficiency in these areas, generate meaningful learning, and influence student attitudes throughout their education.

Identifying Complex Cultural Interactions in the Instructional Design Process: A Case Study of a Cross-Border, Cross-Sector Training for Innovation Program

ERIC Educational Resources Information Center

Russell, L. Roxanne; Kinuthia, Wanjira L.; Lokey-Vega, Anissa; Tsang-Kosma, Winnie; Madathany, Reeny

2013-01-01

The purpose of this research is to identify complex cultural dynamics in the instructional design process of a cross-sector, cross-border training environment by applying Young's (2009) Culture-Based Model (CBM) as a theoretical framework and taxonomy for description of the instructional design process under the conditions of one case. This…

A SAS-based solution to evaluate study design efficiency of phase I pediatric oncology trials via discrete event simulation.

PubMed

Barrett, Jeffrey S; Jayaraman, Bhuvana; Patel, Dimple; Skolnik, Jeffrey M

2008-06-01

Previous exploration of oncology study design efficiency has focused on Markov processes alone (probability-based events) without consideration for time dependencies. Barriers to study completion include time delays associated with patient accrual, inevaluability (IE), time to dose limiting toxicities (DLT) and administrative and review time. Discrete event simulation (DES) can incorporate probability-based assignment of DLT and IE frequency, correlated with cohort in the case of DLT, with time-based events defined by stochastic relationships. A SAS-based solution to examine study efficiency metrics and evaluate design modifications that would improve study efficiency is presented. Virtual patients are simulated with attributes defined from prior distributions of relevant patient characteristics. Study population datasets are read into SAS macros which select patients and enroll them into a study based on the specific design criteria if the study is open to enrollment. Waiting times, arrival times and time to study events are also sampled from prior distributions; post-processing of study simulations is provided within the decision macros and compared across designs in a separate post-processing algorithm. This solution is examined via comparison of the standard 3+3 decision rule relative to the "rolling 6" design, a newly proposed enrollment strategy for the phase I pediatric oncology setting.

Numerical and experimental analysis of a ducted propeller designed by a fully automated optimization process under open water condition

NASA Astrophysics Data System (ADS)

Yu, Long; Druckenbrod, Markus; Greve, Martin; Wang, Ke-qi; Abdel-Maksoud, Moustafa

2015-10-01

A fully automated optimization process is provided for the design of ducted propellers under open water conditions, including 3D geometry modeling, meshing, optimization algorithm and CFD analysis techniques. The developed process allows the direct integration of a RANSE solver in the design stage. A practical ducted propeller design case study is carried out for validation. Numerical simulations and open water tests are fulfilled and proved that the optimum ducted propeller improves hydrodynamic performance as predicted.

The life cycles of six multi-center adaptive clinical trials focused on neurological emergencies developed for the Advancing Regulatory Science initiative of the National Institutes of Health and US Food and Drug Administration: Case studies from the Adaptive Designs Accelerating Promising Treatments Into Trials Project

PubMed Central

Guetterman, Timothy C; Fetters, Michael D; Mawocha, Samkeliso; Legocki, Laurie J; Barsan, William G; Lewis, Roger J; Berry, Donald A; Meurer, William J

2017-01-01

Objectives: Clinical trials are complicated, expensive, time-consuming, and frequently do not lead to discoveries that improve the health of patients with disease. Adaptive clinical trials have emerged as a methodology to provide more flexibility in design elements to better answer scientific questions regarding whether new treatments are efficacious. Limited observational data exist that describe the complex process of designing adaptive clinical trials. To address these issues, the Adaptive Designs Accelerating Promising Treatments Into Trials project developed six, tailored, flexible, adaptive, phase-III clinical trials for neurological emergencies, and investigators prospectively monitored and observed the processes. The objective of this work is to describe the adaptive design development process, the final design, and the current status of the adaptive trial designs that were developed. Methods: To observe and reflect upon the trial development process, we employed a rich, mixed methods evaluation that combined quantitative data from visual analog scale to assess attitudes about adaptive trials, along with in-depth qualitative data about the development process gathered from observations. Results: The Adaptive Designs Accelerating Promising Treatments Into Trials team developed six adaptive clinical trial designs. Across the six designs, 53 attitude surveys were completed at baseline and after the trial planning process completed. Compared to baseline, the participants believed significantly more strongly that the adaptive designs would be accepted by National Institutes of Health review panels and non-researcher clinicians. In addition, after the trial planning process, the participants more strongly believed that the adaptive design would meet the scientific and medical goals of the studies. Conclusion: Introducing the adaptive design at early conceptualization proved critical to successful adoption and implementation of that trial. Involving key stakeholders from several scientific domains early in the process appears to be associated with improved attitudes towards adaptive designs over the life cycle of clinical trial development. PMID:29085638

Experimental Learning Enhancing Improvisation Skills

ERIC Educational Resources Information Center

Pereira Christopoulos, Tania; Wilner, Adriana; Trindade Bestetti, Maria Luisa

2016-01-01

Purpose: This study aims to present improvisation training and experimentation as an alternative method to deal with unexpected events in which structured processes do not seem to work. Design/Methodology/Approach: Based on the literature of sensemaking and improvisation, the study designs a framework and process model of experimental learning…

Making Connections: Building Artistic Insight for Digital Design

ERIC Educational Resources Information Center

Garone, Eugene A.

2010-01-01

Using three groups of community college students, this study addresses the process students Using three groups of community college students, this study addresses the process students use to construe, reformulate, and synthesize knowledge, and discusses the connection between drawing skills, sketching, and digital design production. In addition…

Operationally efficient propulsion system study (OEPSS) data book. Volume 7; Launch Operations Index (LOI) Design Features and Options

NASA Technical Reports Server (NTRS)

Ziese, James M.

1992-01-01

A design tool of figure of merit was developed that allows the operability of a propulsion system design to be measured. This Launch Operations Index (LOI) relates Operations Efficiency to System Complexity. The figure of Merit can be used by conceptual designers to compare different propulsion system designs based on their impact on launch operations. The LOI will improve the design process by making sure direct launch operations experience is a necessary feedback to the design process.

Study on light weight design of truss structures of spacecrafts

NASA Astrophysics Data System (ADS)

Zeng, Fuming; Yang, Jianzhong; Wang, Jian

2015-08-01

Truss structure is usually adopted as the main structure form for spacecrafts due to its high efficiency in supporting concentrated loads. Light-weight design is now becoming the primary concern during conceptual design of spacecrafts. Implementation of light-weight design on truss structure always goes through three processes: topology optimization, size optimization and composites optimization. During each optimization process, appropriate algorithm such as the traditional optimality criterion method, mathematical programming method and the intelligent algorithms which simulate the growth and evolution processes in nature will be selected. According to the practical processes and algorithms, combined with engineering practice and commercial software, summary is made for the implementation of light-weight design on truss structure for spacecrafts.

Improved Image-Guided Laparoscopic Prostatectomy

DTIC Science & Technology

2013-07-01

Automatic robotic-assisted palpation has been designed , implemented and tested. Two studies have been completed: 1) ex-vivo prostate specimens using...concerned with the additional processing of the specimens. We responded by designing a phantom box to improve the process so that pathologists could...of the study will be presented below, at task 3a. Task 3. Design and build new LAPUS probe (months 13-24) Data from the ex-vivo

Development of Souvenir Production Transaction Processing System

NASA Astrophysics Data System (ADS)

Rumambi, H.; Kaparang, R.; Lintong, J.

2018-01-01

This research aims to design a souvenir production transaction processing system for the craftsmen in North Sulawesi. The craftsmen make very simple recordings about souvenir production transactions and use documents that are not in accordance with the generally accepted accounting practices. This research uses qualitative method. The data is collected through interviews, observations, documents and literatures studies. The research stages are conducted in preliminary studies, data collection, data analyzed and system design. The design of system is built from chart of account, accounting cycle and documents as input and get processed in accounting recording. The outputs are financial statements. The system design provides benefits for the craftsmen in assessing the financial performance and getting financing from bank.

Mechatronics Education: From Paper Design to Product Prototype Using LEGO NXT Parts

NASA Astrophysics Data System (ADS)

Lofaro, Daniel M.; Le, Tony Truong Giang; Oh, Paul

The industrial design cycle starts with design then simulation, prototyping, and testing. When the tests do not match the design requirements the design process is started over again. It is important for students to experience this process before they leave their academic institution. The high cost of the prototype phase, due to CNC/Rapid Prototype machine costs, makes hands on study of this process expensive for students and the academic institutions. This document shows that the commercially available LEGO NXT Robot kit is a viable low cost surrogate to the expensive industrial CNC/Rapid Prototype portion of the industrial design cycle.

Interpretive Research Aiming at Theory Building: Adopting and Adapting the Case Study Design

ERIC Educational Resources Information Center

Diaz Andrade, Antonio

2009-01-01

Although the advantages of case study design are widely recognised, its original positivist underlying assumptions may mislead interpretive researchers aiming at theory building. The paper discusses the limitations of the case study design for theory building and explains how grounded theory systemic process adds to the case study design. The…

The Impact of WhatsApp Use on Success in Education Process

ERIC Educational Resources Information Center

Cetinkaya, Levent

2017-01-01

The purpose of this study is to explore the effects of WhatsApp use for education and determine the opinions of students towards the process. The study was designed in mixed research model which combines both qualitative and quantitative data. In the quantitative aspect of the study, quasi-experimental design, with a pretest-posttest control…

Residential Interior Design as Complex Composition: A Case Study of a High School Senior's Composing Process

ERIC Educational Resources Information Center

Smagorinsky, Peter; Zoss, Michelle; Reed, Patty M.

2006-01-01

This research analyzed the composing processes of one high school student as she designed the interiors of homes for a course in interior design. Data included field notes, an interview with the teacher, artifacts from the class, and the focal student's concurrent and retrospective protocols in relation to her design of home interiors. The…

The networked student: A design-based research case study of student constructed personal learning environments in a middle school science course

NASA Astrophysics Data System (ADS)

Drexler, Wendy

This design-based research case study applied a networked learning approach to a seventh grade science class at a public school in the southeastern United States. Students adapted emerging Web applications to construct personal learning environments for in-depth scientific inquiry of poisonous and venomous life forms. The personal learning environments constructed used Application Programming Interface (API) widgets to access, organize, and synthesize content from a number of educational Internet resources and social network connections. This study examined the nature of personal learning environments; the processes students go through during construction, and patterns that emerged. The project was documented from both an instructional and student-design perspective. Findings revealed that students applied the processes of: practicing digital responsibility; practicing digital literacy; organizing content; collaborating and socializing; and synthesizing and creating. These processes informed a model of the networked student that will serve as a framework for future instructional designs. A networked learning approach that incorporates these processes into future designs has implications for student learning, teacher roles, professional development, administrative policies, and delivery. This work is significant in that it shifts the focus from technology innovations based on tools to student empowerment based on the processes required to support learning. It affirms the need for greater attention to digital literacy and responsibility in K12 schools as well as consideration for those skills students will need to achieve success in the 21st century. The design-based research case study provides a set of design principles for teachers to follow when facilitating student construction of personal learning environments.

Methodological considerations in the design and implementation of clinical trials.

PubMed

Cirrincione, Constance T; Lavoie Smith, Ellen M; Pang, Herbert

2014-02-01

To review study design issues related to clinical trials led by oncology nurses, with special attention to those conducted within the cooperative group setting; to emphasize the importance of the statistician's role in the process of clinical trials. Studies available at clinicaltrials.gov using experimental designs that have been published in peer-reviewed journals; cooperative group trials are highlighted. The clinical trial is a primary means to test intervention efficacy. A properly designed and powered study with clear and measurable objectives is as important as the intervention itself. Collaboration among the study team, including the statistician, is central in developing and conducting appropriately designed studies. For optimal results, collaboration is an ongoing process that should begin early on. Copyright © 2014 Elsevier Inc. All rights reserved.

The Influence of Toy Design Activities on Middle School Students' Understanding of the Engineering Design Processes

NASA Astrophysics Data System (ADS)

Zhou, Ninger; Pereira, Nielsen L.; George, Tarun Thomas; Alperovich, Jeffrey; Booth, Joran; Chandrasegaran, Senthil; Tew, Jeffrey David; Kulkarni, Devadatta M.; Ramani, Karthik

2017-10-01

The societal demand for inspiring and engaging science, technology, engineering, and mathematics (STEM) students and preparing our workforce for the emerging creative economy has necessitated developing students' self-efficacy and understanding of engineering design processes from as early as elementary school levels. Hands-on engineering design activities have shown the potential to promote middle school students' self-efficacy and understanding of engineering design processes. However, traditional classrooms often lack hands-on engineering design experiences, leaving students unprepared to solve real-world design problems. In this study, we introduce the framework of a toy design workshop and investigate the influence of the workshop activities on students' understanding of and self-efficacy beliefs in engineering design. Using a mixed method approach, we conducted quantitative analyses to show changes in students' engineering design self-efficacy and qualitative analyses to identify students' understanding of the engineering design processes. Findings show that among the 24 participants, there is a significant increase in students' self-efficacy beliefs after attending the workshop. We also identified major themes such as design goals and prototyping in students' understanding of engineering design processes. This research provides insights into the key elements of middle school students' engineering design learning and the benefits of engaging middle school students in hands-on toy design workshops.

Integrated Bioprocess Design: A Case Study for Undergraduates.

ERIC Educational Resources Information Center

Titchener-Hooker, Nigel; Zhou, Yu-Hong

2000-01-01

Presents a case study for use in the teaching of bioprocess design. Taking the production and isolation of the intracellular protein s. cerevisae, demonstrates how undergraduates can use a range of data to construct and then investigate the range of processes flowsheet options available for a process duty. (Author/SAH)

Application of quality by design concepts in the development of fluidized bed granulation and tableting processes.

PubMed

Djuris, Jelena; Medarevic, Djordje; Krstic, Marko; Djuric, Zorica; Ibric, Svetlana

2013-06-01

This study illustrates the application of experimental design and multivariate data analysis in defining design space for granulation and tableting processes. According to the quality by design concepts, critical quality attributes (CQAs) of granules and tablets, as well as critical parameters of granulation and tableting processes, were identified and evaluated. Acetaminophen was used as the model drug, and one of the study aims was to investigate the possibility of the development of immediate- or extended-release acetaminophen tablets. Granulation experiments were performed in the fluid bed processor using polyethylene oxide polymer as a binder in the direct granulation method. Tablets were compressed in the laboratory excenter tablet press. The first set of experiments was organized according to Plackett-Burman design, followed by the full factorial experimental design. Principal component analysis and partial least squares regression were applied as the multivariate analysis techniques. By using these different methods, CQAs and process parameters were identified and quantified. Furthermore, an in-line method was developed to monitor the temperature during the fluidized bed granulation process, to foresee possible defects in granules CQAs. Various control strategies that are based on the process understanding and assure desired quality attributes of the product are proposed. Copyright © 2013 Wiley Periodicals, Inc.

Rapid Geometry Creation for Computer-Aided Engineering Parametric Analyses: A Case Study Using ComGeom2 for Launch Abort System Design

NASA Technical Reports Server (NTRS)

Hawke, Veronica; Gage, Peter; Manning, Ted

2007-01-01

ComGeom2, a tool developed to generate Common Geometry representation for multidisciplinary analysis, has been used to create a large set of geometries for use in a design study requiring analysis by two computational codes. This paper describes the process used to generate the large number of configurations and suggests ways to further automate the process and make it more efficient for future studies. The design geometry for this study is the launch abort system of the NASA Crew Launch Vehicle.

Human Engineering of Space Vehicle Displays and Controls

NASA Technical Reports Server (NTRS)

Whitmore, Mihriban; Holden, Kritina L.; Boyer, Jennifer; Stephens, John-Paul; Ezer, Neta; Sandor, Aniko

2010-01-01

Proper attention to the integration of the human needs in the vehicle displays and controls design process creates a safe and productive environment for crew. Although this integration is critical for all phases of flight, for crew interfaces that are used during dynamic phases (e.g., ascent and entry), the integration is particularly important because of demanding environmental conditions. This panel addresses the process of how human engineering involvement ensures that human-system integration occurs early in the design and development process and continues throughout the lifecycle of a vehicle. This process includes the development of requirements and quantitative metrics to measure design success, research on fundamental design questions, human-in-the-loop evaluations, and iterative design. Processes and results from research on displays and controls; the creation and validation of usability, workload, and consistency metrics; and the design and evaluation of crew interfaces for NASA's Crew Exploration Vehicle are used as case studies.

We get the algorithms of our ground truths: Designing referential databases in digital image processing

PubMed Central

Jaton, Florian

2017-01-01

This article documents the practical efforts of a group of scientists designing an image-processing algorithm for saliency detection. By following the actors of this computer science project, the article shows that the problems often considered to be the starting points of computational models are in fact provisional results of time-consuming, collective and highly material processes that engage habits, desires, skills and values. In the project being studied, problematization processes lead to the constitution of referential databases called ‘ground truths’ that enable both the effective shaping of algorithms and the evaluation of their performances. Working as important common touchstones for research communities in image processing, the ground truths are inherited from prior problematization processes and may be imparted to subsequent ones. The ethnographic results of this study suggest two complementary analytical perspectives on algorithms: (1) an ‘axiomatic’ perspective that understands algorithms as sets of instructions designed to solve given problems computationally in the best possible way, and (2) a ‘problem-oriented’ perspective that understands algorithms as sets of instructions designed to computationally retrieve outputs designed and designated during specific problematization processes. If the axiomatic perspective on algorithms puts the emphasis on the numerical transformations of inputs into outputs, the problem-oriented perspective puts the emphasis on the definition of both inputs and outputs. PMID:28950802

Making the case for evidence-based design in healthcare: a descriptive case study of organizational decision making.

PubMed

Shoemaker, Lorie K; Kazley, Abby Swanson; White, Andrea

2010-01-01

The aim of this study was to describe the organizational decision-making process used in the selection of evidence-based design (EBD) concepts, the criteria used to make these decisions, and the extent to which leadership style may have influenced the decision-making process. Five research questions were formulated to frame the direction of this study, including: (1) How did healthcare leaders learn of innovations in design? (2) How did healthcare leaders make decisions in the selection of healthcare design concepts? (3) What criteria did healthcare leaders use in the decision-making process? (4) How did healthcare leaders consider input from the staff in design decisions? and (5) To what extent did the leadership style of administrators affect the outcomes of the decision-making process? Current issues affecting healthcare in the community led the principal investigator's organization to undertake an ambitious facilities expansion project. As part of its planning process, the organization learned of EBD principles that seemingly had a positive impact on patient care and safety and staff working conditions. Although promising, a paucity of empirical research addressed the cost/benefit of incorporating many EBD concepts into one hospital setting, and there was no research that articulated the organizational decision-making process used by healthcare administrators when considering the use of EBD in expansion projects. A mixed-method, descriptive, qualitative, single-case study and quantitative design were used to address the five research questions. The Systems Research Organizing Model provided the theoretical framework. A variety of data collection methods was used, including interviews of key respondents, the review of documentary evidence, and the Multifactor Leadership Questionnaire. A participatory process was used throughout the design decision phases, involving staff at all levels of the organization. The Internet and architects facilitated learning about EBD. Financial considerations were a factor in decision making. The prevalence of the transformational leadership style among the organization's administrators exceeded the U.S. mean.

A novel double loop control model design for chemical unstable processes.

PubMed

Cong, Er-Ding; Hu, Ming-Hui; Tu, Shan-Tung; Xuan, Fu-Zhen; Shao, Hui-He

2014-03-01

In this manuscript, based on Smith predictor control scheme for unstable process in industry, an improved double loop control model is proposed for chemical unstable processes. Inner loop is to stabilize integrating the unstable process and transform the original process to first-order plus pure dead-time dynamic stable process. Outer loop is to enhance the performance of set point response. Disturbance controller is designed to enhance the performance of disturbance response. The improved control system is simple with exact physical meaning. The characteristic equation is easy to realize stabilization. Three controllers are separately design in the improved scheme. It is easy to design each controller and good control performance for the respective closed-loop transfer function separately. The robust stability of the proposed control scheme is analyzed. Finally, case studies illustrate that the improved method can give better system performance than existing design methods. © 2013 ISA Published by ISA All rights reserved.

A methodological framework to support the initiation, design and institutionalization of participatory modeling processes in water resources management

NASA Astrophysics Data System (ADS)

Halbe, Johannes; Pahl-Wostl, Claudia; Adamowski, Jan

2018-01-01

Multiple barriers constrain the widespread application of participatory methods in water management, including the more technical focus of most water agencies, additional cost and time requirements for stakeholder involvement, as well as institutional structures that impede collaborative management. This paper presents a stepwise methodological framework that addresses the challenges of context-sensitive initiation, design and institutionalization of participatory modeling processes. The methodological framework consists of five successive stages: (1) problem framing and stakeholder analysis, (2) process design, (3) individual modeling, (4) group model building, and (5) institutionalized participatory modeling. The Management and Transition Framework is used for problem diagnosis (Stage One), context-sensitive process design (Stage Two) and analysis of requirements for the institutionalization of participatory water management (Stage Five). Conceptual modeling is used to initiate participatory modeling processes (Stage Three) and ensure a high compatibility with quantitative modeling approaches (Stage Four). This paper describes the proposed participatory model building (PMB) framework and provides a case study of its application in Québec, Canada. The results of the Québec study demonstrate the applicability of the PMB framework for initiating and designing participatory model building processes and analyzing barriers towards institutionalization.

Empirical studies of software design: Implications for SSEs

NASA Technical Reports Server (NTRS)

Krasner, Herb

1988-01-01

Implications for Software Engineering Environments (SEEs) are presented in viewgraph format for characteristics of projects studied; significant problems and crucial problem areas in software design for large systems; layered behavioral model of software processes; implications of field study results; software project as an ecological system; results of the LIFT study; information model of design exploration; software design strategies; results of the team design study; and a list of publications.

Spatial information is processed even when it is task-irrelevant: implications for neuroimaging task design.

PubMed

Meegan, Daniel V; Honsberger, Michael J M

2005-05-01

Many neuroimaging studies have been designed to differentiate domain-specific processes in the brain. A common design constraint is to use identical stimuli for different domain-specific tasks. For example, an experiment investigating spatial versus identity processing would present compound spatial-identity stimuli in both spatial and identity tasks, and participants would be instructed to attend to, encode, maintain, or retrieve spatial information in the spatial task, and identity information in the identity task. An assumption in such studies is that spatial information will not be processed in the identity task, as it is irrelevant for that task. We report three experiments demonstrating violations of this assumption. Our results suggest that comparisons of spatial and identity tasks in existing neuroimaging studies have underestimated the amount of brain activation that is spatial-specific. For future neuroimaging studies, we recommend unique stimulus displays for each domain-specific task, and event-related measurement of post-stimulus processing.

An MBE growth facility for real-time in situ synchrotron x-ray topography studies of strained-layer III-V epitaxial materials

NASA Astrophysics Data System (ADS)

Whitehouse, C. R.; Barnett, S. J.; Soley, D. E. J.; Quarrell, J.; Aldridge, S. J.; Cullis, A. G.; Emeny, M. T.; Johnson, A. D.; Clarke, G. F.; Lamb, W.; Tanner, B. K.; Cottrell, S.; Lunn, B.; Hogg, C.; Hagston, W.

1992-01-01

This paper describes a unique combined UHV MBE growth x-ray topography facility designed to allow the first real-time synchrotron radiation x-ray topography study of strained-layer III-V growth processes. This system will enable unambiguous determination of dislocation nucleation and multiplication processes as a function of controlled variations in growth conditions, and also during post-growth thermal processing. The planned experiments have placed very stringent demands upon the engineering design of the system, and design details regarding the growth chamber; sample manipulator, x-ray optics, and real-time imaging systems are described. Results obtained during a feasibility study are also presented.

An MBE growth facility for real-time in situ synchrotron x-ray topography studies of strained-layer III--V epitaxial materials

DOE Office of Scientific and Technical Information (OSTI.GOV)

Whitehouse, C.R.; Barnett, S.J.; Soley, D.E.J.

1992-01-01

This paper describes a unique combined UHV MBE growth x-ray topography facility designed to allow the first real-time synchrotron radiation x-ray topography study of strained-layer III--V growth processes. This system will enable unambiguous determination of dislocation nucleation and multiplication processes as a function of controlled variations in growth conditions, and also during post-growth thermal processing. The planned experiments have placed very stringent demands upon the engineering design of the system, and design details regarding the growth chamber; sample manipulator, x-ray optics, and real-time imaging systems are described. Results obtained during a feasibility study are also presented.

Verifying and Validating Proposed Models for FSW Process Optimization

NASA Technical Reports Server (NTRS)

Schneider, Judith

2008-01-01

This slide presentation reviews Friction Stir Welding (FSW) and the attempts to model the process in order to optimize and improve the process. The studies are ongoing to validate and refine the model of metal flow in the FSW process. There are slides showing the conventional FSW process, a couple of weld tool designs and how the design interacts with the metal flow path. The two basic components of the weld tool are shown, along with geometries of the shoulder design. Modeling of the FSW process is reviewed. Other topics include (1) Microstructure features, (2) Flow Streamlines, (3) Steady-state Nature, and (4) Grain Refinement Mechanisms

A case study of the influences of audience and purpose on the composing processes of an engineer

NASA Technical Reports Server (NTRS)

Stalnaker, B. J.

1981-01-01

The design and preliminary findings of a study of composing processes (on the job) of engineers, managers, and scientists is presented. The influences of audience and purpose on the composing process of engineers was of concern; specifically, the cognitive processes, physical behaviors, and factors that influence the evoluton of a piece of writing. An overview of the study, related literature, outlines of research design, and preliminary findings from a case study of engineers are given. It is suggested that teaching be adapted to help students learn to represent rhetorical problems to guide composing for effective writing.

Aesthetic Pleasure versus Aesthetic Interest: The Two Routes to Aesthetic Liking

PubMed Central

Graf, Laura K. M.; Landwehr, Jan R.

2017-01-01

Although existing research has established that aesthetic pleasure and aesthetic interest are two distinct positive aesthetic responses, empirical research on aesthetic preferences usually considers only aesthetic liking to capture participants’ aesthetic response. This causes some fundamental contradictions in the literature; some studies find a positive relationship between easy-to-process stimulus characteristics and aesthetic liking, while others suggest a negative relationship. The present research addresses these empirical contradictions by investigating the dual character of aesthetic liking as manifested in both the pleasure and interest components. Based on the Pleasure-Interest Model of Aesthetic Liking (PIA Model; Graf and Landwehr, 2015), two studies investigated the formation of pleasure and interest and their relationship with aesthetic liking responses. Using abstract art as the stimuli, Study 1 employed a 3 (stimulus fluency: low, medium, high) × 2 (processing style: automatic, controlled) × 2 (aesthetic response: pleasure, interest) experimental design to examine the processing dynamics responsible for experiencing aesthetic pleasure versus aesthetic interest. We find that the effect of stimulus fluency on pleasure is mediated by a gut-level fluency experience. Stimulus fluency and interest, by contrast, are related through a process of disfluency reduction, such that disfluent stimuli that grow more fluent due to processing efforts become interesting. The second study employed product designs (bikes, chairs, and lamps) as stimuli and a 2 (fluency: low, high) × 2 (processing style: automatic, controlled) × 3 (product type: bike, chair, lamp) experimental design to examine pleasure and interest as mediators of the relationship between stimulus fluency and design attractiveness. With respect to lamps and chairs, the results suggest that the effect of stimulus fluency on attractiveness is fully mediated by aesthetic pleasure, especially in the automatic processing style. Conversely, disfluent product designs can enhance design attractiveness judgments due to interest when a controlled processing style is adopted. PMID:28194119

Comparing Freshman and doctoral engineering students in design: mapping with a descriptive framework

NASA Astrophysics Data System (ADS)

Carmona Marques, P.

2017-11-01

This paper reports the results of a study of engineering students' approaches to an open-ended design problem. To carry out this, sketches and interviews were collected from 9 freshmen (first year) and 10 doctoral engineering students, when they designed solutions for orange squeezers. Sketches and interviews were analysed and mapped with a descriptive 'ideation framework' (IF) of the design process, to document and compare their design creativity (Carmona Marques, P., A. Silva, E. Henriques, and C. Magee. 2014. "A Descriptive Framework of the Design Process from a Dual Cognitive Engineering Perspective." International Journal of Design Creativity and Innovation 2 (3): 142-164). The results show that the designers worked in a manner largely consistent with the IF for generalisation and specialisation loops. Also, doctoral students produced more alternative solutions during the ideation process. In addition, compared to freshman, doctoral used the generalisation loop of the IF, working at higher levels of abstraction. The iterative nature of design is highlighted during this study - a potential contribution to decrease the gap between both groups in engineering education.

Breadth in Design Problem Scoping: Using Insights from Experts to Investigate Student Processes. Research Brief

ERIC Educational Resources Information Center

Morozov, Andrew; Kilgore, Deborah; Atman, Cynthia

2007-01-01

In this study, the authors used two methods for analyzing expert data: verbal protocol analysis (VPA) and narrative analysis. VPA has been effectively used to describe the design processes employed by engineering students, expert designers, and expert-novice comparative research. VPA involves asking participants to "think aloud" while…

Study and Test to Confirm Automobile Drivetrain Components to Improve Fuel Economy : Volume 2. The Drivetrain Design Process With an Automatic Transmission

DOT National Transportation Integrated Search

1979-05-01

This report presents the key thought processes that are used by the drivetrain designer in matching an engine to a given vehicle with specific performance goals in mind. This report provides those uninitiated in this aspect of automotive design valua...

GUIDE FOR CONDUCTING TREATABILITY STUDIES UNDER CERCLA

EPA Science Inventory

Systematically conducted, well-documented treatability studies are an important component of the removal process, remedial investigation/ feasibility study (RI/FS) process and the remedial design/remedial action (RD/RA) process under the Comprehensive Environmental Response...

The Metamorphosis of Industrial Designers from Novices to Experts

ERIC Educational Resources Information Center

Wong, Ju-Joan; Chen, Po-Yu; Chen, Chun-Di

2016-01-01

Professional training for designers is crucial in the field of design studies. The characteristics of novices versus those of expert designers have been identified in the literature; however, studies exploring the issue of professional training processes in the actual workplace are not well developed. Our study addresses the topic by using…

What are you trying to learn? Study designs and the appropriate analysis for your research question

USDA-ARS?s Scientific Manuscript database

One fundamental necessity in the entire process of a well-performed study is the experimental design. A well-designed study can help researchers understand and have confidence in their results and analyses, and additionally the agreement or disagreement with the stated hypothesis. This well-designed...

Integrating ergonomics into engineering design: the role of objects.

PubMed

Hall-Andersen, Lene Bjerg; Broberg, Ole

2014-05-01

The objective of this study was to explore the role of objects in integrating ergonomic knowledge in engineering design processes. An engineering design case was analyzed using the theoretical concepts of boundary objects and intermediary objects: Boundary objects facilitate collaboration between different knowledge domains, while the aim of an intermediary object is to circulate knowledge and thus produce a distant effect. Adjustable layout drawings served as boundary objects and had a positive impact on the dialog between an ergonomist and designers. An ergonomic guideline document was identified as an intermediary object. However, when the ergonomic guidelines were circulated in the design process, only some of the guidelines were transferred to the design of the sterile processing plant. Based on these findings, recommendations for working with objects in design processes are included. Copyright © 2013 Elsevier Ltd and The Ergonomics Society. All rights reserved.

Move the Neighbourhood: Study design of a community-based participatory public open space intervention in a Danish deprived neighbourhood to promote active living.

PubMed

Pawlowski, Charlotte Skau; Winge, Laura; Carroll, Sidse; Schmidt, Tanja; Wagner, Anne Margrethe; Nørtoft, Kamilla Pernille Johansen; Lamm, Bettina; Kural, René; Schipperijn, Jasper; Troelsen, Jens

2017-05-19

A limited amount of research has examined the effect of changing public open spaces on active living. This paper will present the study protocol of a community-based intervention study co-designed in an interdisciplinary collaboration with community members to develop urban installations highly tailored to promote active living among children (10-13-years-old) and seniors (>60-years-old) in a deprived neighbourhood in Copenhagen. The study builds on a quasi-experimental study design with two sub-studies: 1) a children study and 2) a senior study. The interventions will be developed, designed and implemented in collaboration with local children and seniors, respectively, using different co-design tools and methods. We will evaluate the effect of the interventions on children's and senior's use of the new-built urban installations using accelerometers in combination with GPS as well as systematic observation using the System for Observing Play and Recreation in Communities (SOPARC). A process evaluation with focus groups consisting of the various stakeholders in the two sub-studies will be used to gain knowledge of the intervention processes. The paper presents new approaches in the field of public open space interventions through interdisciplinary collaboration, participatory co-design approach and combination of measurements. Using both effect and process evaluations the study will provide unique insights in the role and importance of the interdisciplinary collaboration, participatory processes, and tailoring changes in public open space to local needs and wishes. These results can be used to guide urban renewal projects in deprived neighbourhoods in the future. Retrospectively registered with study ID ISRCTN50036837 . Date of registration: 16 December 2016.

Feasibility study of an Integrated Program for Aerospace vehicle Design (IPAD). Volume 1B: Concise review

NASA Technical Reports Server (NTRS)

Miller, R. E., Jr.; Southall, J. W.; Kawaguchi, A. S.; Redhed, D. D.

1973-01-01

Reports on the design process, support of the design process, IPAD System design catalog of IPAD technical program elements, IPAD System development and operation, and IPAD benefits and impact are concisely reviewed. The approach used to define the design is described. Major activities performed during the product development cycle are identified. The computer system requirements necessary to support the design process are given as computational requirements of the host system, technical program elements and system features. The IPAD computer system design is presented as concepts, a functional description and an organizational diagram of its major components. The cost and schedules and a three phase plan for IPAD implementation are presented. The benefits and impact of IPAD technology are discussed.

Guidelines for Transferring Residential Courses into Web

ERIC Educational Resources Information Center

Tüzün, Hakan; Çinar, Murat

2016-01-01

This study shared unique design experiences by examining the process of transferring residential courses to the Web, and proposed a design model for individuals who want to transfer their courses into this environment. The formative research method was used in the study, and two project teams' processes of putting courses, which were being taught…

Feasibility study of an Integrated Program for Aerospace-vehicle Design (IPAD) system. Volume 3: Engineering creative/evaluation processes, phase 1, task 2

NASA Technical Reports Server (NTRS)

Garrocq, C. A.; Hosek, J. J.

1973-01-01

A series of functional flow charts are considered that were developed to properly identify and record the degree of participation of the disciplines considered in this feasibility study and the type of data required in the design process.

Cognitive Process as a Basis for Intelligent Retrieval Systems Design.

ERIC Educational Resources Information Center

Chen, Hsinchun; Dhar, Vasant

1991-01-01

Two studies of the cognitive processes involved in online document-based information retrieval were conducted. These studies led to the development of five computational models of online document retrieval which were incorporated into the design of an "intelligent" document-based retrieval system. Both the system and the broader implications of…

Design principles for simulation games for learning clinical reasoning: A design-based research approach.

PubMed

Koivisto, J-M; Haavisto, E; Niemi, H; Haho, P; Nylund, S; Multisilta, J

2018-01-01

Nurses sometimes lack the competence needed for recognising deterioration in patient conditions and this is often due to poor clinical reasoning. There is a need to develop new possibilities for learning this crucial competence area. In addition, educators need to be future oriented; they need to be able to design and adopt new pedagogical innovations. The purpose of the study is to describe the development process and to generate principles for the design of nursing simulation games. A design-based research methodology is applied in this study. Iterative cycles of analysis, design, development, testing and refinement were conducted via collaboration among researchers, educators, students, and game designers. The study facilitated the generation of reusable design principles for simulation games to guide future designers when designing and developing simulation games for learning clinical reasoning. This study makes a major contribution to research on simulation game development in the field of nursing education. The results of this study provide important insights into the significance of involving nurse educators in the design and development process of educational simulation games for the purpose of nursing education. Copyright © 2017 Elsevier Ltd. All rights reserved.

Three-Dimensional Finite Element Ablative Thermal Response and Thermostructural Design of Thermal Protection Systems

NASA Technical Reports Server (NTRS)

Dec, John A.; Braun, Robert D.

2011-01-01

A finite element ablation and thermal response program is presented for simulation of three-dimensional transient thermostructural analysis. The three-dimensional governing differential equations and finite element formulation are summarized. A novel probabilistic design methodology for thermal protection systems is presented. The design methodology is an eight step process beginning with a parameter sensitivity study and is followed by a deterministic analysis whereby an optimum design can determined. The design process concludes with a Monte Carlo simulation where the probabilities of exceeding design specifications are estimated. The design methodology is demonstrated by applying the methodology to the carbon phenolic compression pads of the Crew Exploration Vehicle. The maximum allowed values of bondline temperature and tensile stress are used as the design specifications in this study.

Key issues in theoretical and functional pneumatic design

NASA Astrophysics Data System (ADS)

Xu, Z. G.; Yang, D. Y.; Liu, W. M.; Liu, T. T.

2017-10-01

This paper studies the energy release of the pneumatic engine in different thermodynamic processes, the isothermal process is the highest power output process, while adiabatic process is the lowest energy output process, and the energy release of the pneumatic engine is a multi-state thermodynamic process between them. Therefore heat exchanging should be increased between the pneumatic engine and the outer space, the gas expansion process in the cylinder should be as close as possible to the isothermal process. Heat exchange should be increased between the cylinder and the external spaces. Secondly, the fin structure is studied to increase the heat exchanging between the cylinder body and the outside space. The upper part has fin structures and the lower cylinder has no fin structure, this structure improved the working efficiency of pneumatic engine. Finally the cam and the hydraulic bottle of pneumatic engines are designed. Simulation and theoretical calculation are used to the analysis of the whole structure, which lay the foundation for the manufacturing and design of the pneumatic engines.

Improving Design Understandings and Skills through Enhanced Metacognition: Reflective Design Journals

ERIC Educational Resources Information Center

Kurt, Mustafa; Kurt, Sevinc

2017-01-01

The main aim of this study was to investigate and discover whether going through the process of reflection by keeping reflective design journals (RDJ) enhances architecture students' metacognition and whether this enhanced metacognition improves their design understandings and skills. The study was a mixed-methods design and utilised content…

A framework of knowledge creation processes in participatory simulation of hospital work systems.

PubMed

Andersen, Simone Nyholm; Broberg, Ole

2017-04-01

Participatory simulation (PS) is a method to involve workers in simulating and designing their own future work system. Existing PS studies have focused on analysing the outcome, and minimal attention has been devoted to the process of creating this outcome. In order to study this process, we suggest applying a knowledge creation perspective. The aim of this study was to develop a framework describing the process of how ergonomics knowledge is created in PS. Video recordings from three projects applying PS of hospital work systems constituted the foundation of process mining analysis. The analysis resulted in a framework revealing the sources of ergonomics knowledge creation as sequential relationships between the activities of simulation participants sharing work experiences; experimenting with scenarios; and reflecting on ergonomics consequences. We argue that this framework reveals the hidden steps of PS that are essential when planning and facilitating PS that aims at designing work systems. Practitioner Summary: When facilitating participatory simulation (PS) in work system design, achieving an understanding of the PS process is essential. By applying a knowledge creation perspective and process mining, we investigated the knowledge-creating activities constituting the PS process. The analysis resulted in a framework of the knowledge-creating process in PS.

Architectural design of the science complex at Elizabeth City State University

NASA Technical Reports Server (NTRS)

Jahromi, Soheila

1993-01-01

This paper gives an overall view of the architectural design process and elements in taking an idea from conception to execution. The project presented is an example for this process. Once the need for a new structure is established, an architect studies the requirements, opinions and limits in creating a structure that people will exist in, move through, and use. Elements in designing a building include factors such as volume and surface, light and form changes of scale and view, movement and stasis. Some of the other factors are functions and physical conditions of construction. Based on experience, intuition, and boundaries, an architect will utilize all elements in creating a new building. In general, the design process begins with studying the spatial needs which develop into an architectural program. A comprehensive and accurate architectural program is essential for having a successful building. The most attractive building which does not meet the functional needs of its users has failed at the primary reason for its existence. To have a good program an architect must have a full understanding of the daily functions that will take place in the building. The architectural program along with site characteristics are among a few of the important guidelines in studying the form, adjacencies, and circulation for the structure itself and also in relation to the adjacent structures. Conceptual studies are part of the schematic design, which is the first milestone in the design process. The other reference points are design development and construction documents. At each milestone, review and coordination with all the consultants is established, and the user is essential in refining the project. In design development phase, conceptual diagrams take shape, and architectural, structural, mechanical, and electrical systems are developed. The final phase construction documents convey all the information required to construct the building. The design process and elements described were applied in the following project.

An Altair Overview: Designing a Lunar Lander for 21st Century Human Space Exploration

NASA Technical Reports Server (NTRS)

Brown, Kendall K.; Connolly, John F.

2012-01-01

Altair, the lunar lander element of NASA's Constellation program, was conducted in a different design environment than many other NASA projects of similar scope. Because of this relatively unique approach, there are a number of significant success stories that should be considered during the development of any future lunar landers or human spacecraft. This paper is divided into two separate themes; the first is the approach used during the conceptual design studies, including the systematic analysis cycles and the decision making process associated with each: and the second is a summary of the resulting lessons learned that were compiled after looking back at the lifetime of the Project. Altair was terminated before entering Phase B of its design, and was often criticized for being a very heavy and very large vehicle. While there was specific rationale for all of the decisions that led up to that configuration, future design cycles were specifically planned to re-address the mass challenge. Had the project continued, the deliberate, stepwise design process would have converged on an optimized lander design that balanced mass, risk, cost and capabilities. Some of the specific items that will be addressed in this paper include project development strategy, organizational approach and team dynamics, risk-informed design process, mission architecture constraints, mission key driving requirements, model-based systems engineering process, configuration studies, contingency considerations, subsystem overviews and key trade studies. The paper will conclude with a summary of the lessons identified during the Altair project and make suggestions for application to future studies.

Development of deployable structures for large space platform systems. Volume 1: Executive summary

NASA Technical Reports Server (NTRS)

Greenberg, H. S.

1983-01-01

The preponderance of study effort was devoted toward the deployable platform systems study which culminated in the detailed design of a ground test article for future development testing. This design is representative of a prototype square-truss, single-fold building-block design that can construct deployable platform structures. This prototype design was selected through a comprehensive and traceable selection process applied to eight competitive designs. The selection process compared the competitive designs according to seven major selection criteria, i.e., design versatility, cost, thermal stability, meteoroid impact significance, reliability, performance predictability, and orbiter integration suitability. In support of the foregoing, a materials data base, and platform systems technology development needs were established. An erectable design of an OTV hangar was selected and recommended for further design development. This design was selected from five study-developed competitive single-fold and double-fold designs including hard-shell and inflatable designs. Also, two deployable manned module configurations, i.e., a hard-shell and an inflatable design were each developed to the same requirements as the composite of two Space station baseline habitat modules.

Small Column Ion Exchange Design and Safety Strategy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Huff, T.; Rios-Armstrong, M.; Edwards, R.

2011-02-07

Small Column Ion Exchange (SCIX) is a transformational technology originally developed by the Department of Energy (DOE) Environmental Management (EM-30) office and is now being deployed at the Savannah River Site (SRS) to significantly increase overall salt processing capacity and accelerate the Liquid Waste System life-cycle. The process combines strontium and actinide removal using Monosodium Titanate (MST), Rotary Microfiltration, and cesium removal using Crystalline Silicotitanate (CST, specifically UOP IONSIV{reg_sign}IE-911 ion exchanger) to create a low level waste stream to be disposed in grout and a high level waste stream to be vitrified. The process also includes preparation of the streamsmore » for disposal, e.g., grinding of the loaded CST material. These waste processing components are technically mature and flowsheet integration studies are being performed including glass formulations studies, application specific thermal modeling, and mixing studies. The deployment program includes design and fabrication of the Rotary Microfilter (RMF) assembly, ion-exchange columns (IXCs), and grinder module, utilizing an integrated system safety design approach. The design concept is to install the process inside an existing waste tank, Tank 41H. The process consists of a feed pump with a set of four RMFs, two IXCs, a media grinder, three Submersible Mixer Pumps (SMPs), and all supporting infrastructure including media receipt and preparation facilities. The design addresses MST mixing to achieve the required strontium and actinide removal and to prevent future retrieval problems. CST achieves very high cesium loadings (up to 1,100 curies per gallon (Ci/gal) bed volume). The design addresses the hazards associated with this material including heat management (in column and in-tank), as detailed in the thermal modeling. The CST must be size reduced for compatibility with downstream processes. The design addresses material transport into and out of the grinder and includes provisions for equipment maintenance including remote handling. The design includes a robust set of nuclear safety controls compliant with DOE Standard (STD)-1189, Integration of Safety into the Design Process. The controls cover explosions, spills, boiling, aerosolization, and criticality. Natural Phenomena Hazards (NPH) including seismic event, tornado/high wind, and wildland fire are considered. In addition, the SCIX process equipment was evaluated for impact to existing facility safety equipment including the waste tank itself. SCIX is an innovative program which leverages DOE's technology development capabilities to provide a basis for a successful field deployment.« less

Model medication management process in Australian nursing homes using business process modeling.

PubMed

Qian, Siyu; Yu, Ping

2013-01-01

One of the reasons for end user avoidance or rejection to use health information systems is poor alignment of the system with healthcare workflow, likely causing by system designers' lack of thorough understanding about healthcare process. Therefore, understanding the healthcare workflow is the essential first step for the design of optimal technologies that will enable care staff to complete the intended tasks faster and better. The often use of multiple or "high risk" medicines by older people in nursing homes has the potential to increase medication error rate. To facilitate the design of information systems with most potential to improve patient safety, this study aims to understand medication management process in nursing homes using business process modeling method. The paper presents study design and preliminary findings from interviewing two registered nurses, who were team leaders in two nursing homes. Although there were subtle differences in medication management between the two homes, major medication management activities were similar. Further field observation will be conducted. Based on the data collected from observations, an as-is process model for medication management will be developed.

Reflections on the Adaptive Designs Accelerating Promising Trials Into Treatments (ADAPT-IT) Process—Findings from a Qualitative Study

PubMed Central

Guetterman, Timothy C.; Fetters, Michael D.; Legocki, Laurie J.; Mawocha, Samkeliso; Barsan, William G.; Lewis, Roger J.; Berry, Donald A.; Meurer, William J.

2015-01-01

Context The context for this study was the Adaptive Designs Advancing Promising Treatments Into Trials (ADAPT-IT) project, which aimed to incorporate flexible adaptive designs into pivotal clinical trials and to conduct an assessment of the trial development process. Little research provides guidance to academic institutions in planning adaptive trials. Objectives The purpose of this qualitative study was to explore the perspectives and experiences of stakeholders as they reflected back about the interactive ADAPT-IT adaptive design development process, and to understand their perspectives regarding lessons learned about the design of the trials and trial development. Materials and methods We conducted semi-structured interviews with ten key stakeholders and observations of the process. We employed qualitative thematic text data analysis to reduce the data into themes about the ADAPT-IT project and adaptive clinical trials. Results The qualitative analysis revealed four themes: education of the project participants, how the process evolved with participant feedback, procedures that could enhance the development of other trials, and education of the broader research community. Discussion and conclusions While participants became more likely to consider flexible adaptive designs, additional education is needed to both understand the adaptive methodology and articulate it when planning trials. PMID:26622163

Development of hybrid lifecycle cost estimating tool (HLCET) for manufacturing influenced design tradeoff

NASA Astrophysics Data System (ADS)

Sirirojvisuth, Apinut

In complex aerospace system design, making an effective design decision requires multidisciplinary knowledge from both product and process perspectives. Integrating manufacturing considerations into the design process is most valuable during the early design stages since designers have more freedom to integrate new ideas when changes are relatively inexpensive in terms of time and effort. Several metrics related to manufacturability are cost, time, and manufacturing readiness level (MRL). Yet, there is a lack of structured methodology that quantifies how changes in the design decisions impact these metrics. As a result, a new set of integrated cost analysis tools are proposed in this study to quantify the impacts. Equally important is the capability to integrate this new cost tool into the existing design methodologies without sacrificing agility and flexibility required during the early design phases. To demonstrate the applicability of this concept, a ModelCenter environment is used to develop software architecture that represents Integrated Product and Process Development (IPPD) methodology used in several aerospace systems designs. The environment seamlessly integrates product and process analysis tools and makes effective transition from one design phase to the other while retaining knowledge gained a priori. Then, an advanced cost estimating tool called Hybrid Lifecycle Cost Estimating Tool (HLCET), a hybrid combination of weight-, process-, and activity-based estimating techniques, is integrated with the design framework. A new weight-based lifecycle cost model is created based on Tailored Cost Model (TCM) equations [3]. This lifecycle cost tool estimates the program cost based on vehicle component weights and programmatic assumptions. Additional high fidelity cost tools like process-based and activity-based cost analysis methods can be used to modify the baseline TCM result as more knowledge is accumulated over design iterations. Therefore, with this concept, the additional manufacturing knowledge can be used to identify a more accurate lifecycle cost and facilitate higher fidelity tradeoffs during conceptual and preliminary design. Advanced Composite Cost Estimating Model (ACCEM) is employed as a process-based cost component to replace the original TCM result of the composite part production cost. The reason for the replacement is that TCM estimates production costs from part weights as a result of subtractive manufacturing of metallic origin such as casting, forging, and machining processes. A complexity factor can sometimes be adjusted to reflect different types of metal and machine settings. The TCM assumption, however, gives erroneous results when applied to additive processes like those of composite manufacturing. Another innovative aspect of this research is the introduction of a work measurement technique called Maynard Operation Sequence Technique (MOST) to be used, similarly to Activity-Based Costing (ABC) approach, to estimate manufacturing time of a part by virtue of breaking down the operations occurred during its production. ABC allows a realistic determination of cost incurred in each activity, as opposed to using a traditional method of time estimation by analogy or using response surface equations from historical process data. The MOST concept provides a tailored study of an individual process typically required for a new, innovative design. Nevertheless, the MOST idea has some challenges, one of which is its requirement to build a new process from ground up. The process development requires a Subject Matter Expertise (SME) in manufacturing method of the particular design. The SME must have also a comprehensive understanding of the MOST system so that the correct parameters are chosen. In practice, these knowledge requirements may demand people from outside of the design discipline and a priori training of MOST. To relieve the constraint, this study includes an entirely new sub-system architecture that comprises 1) a knowledge-based system to provide the required knowledge during the process selection; and 2) a new user-interface to guide the parameter selection when building the process using MOST. Also included in this study is the demonstration of how the HLCET and its constituents can be integrated with a Georgia Tech' Integrated Product and Process Development (IPPD) methodology. The applicability of this work will be shown through a complex aerospace design example to gain insights into how manufacturing knowledge helps make better design decisions during the early stages. The setup process is explained with an example of its utility demonstrated in a hypothetical fighter aircraft wing redesign. The evaluation of the system effectiveness against existing methodologies is illustrated to conclude the thesis.

Fire Hazard Assessment in Supporting Fire Protection System Design of a Chemical Process Facility

DTIC Science & Technology

1996-08-01

CSDP/Studies/FireHaz –i– 3/28/97 FIRE HAZARD ASSESSMENT IN SUPPORTING FIRE PROTECTION SYSTEM DESIGN OF A CHEMICAL PROCESS FACILITY Ali Pezeshk...Joseph Chang, Dwight Hunt, and Peter Jahn Parsons Infrastructure & Technology Group, Inc. Pasadena, California 91124 ABSTRACT Because fires in a chemical ...Assessment in Supporting Fire Protection System Design of a Chemical Process Facility 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6

Ku-band signal design study. [space shuttle orbiter data processing network

NASA Technical Reports Server (NTRS)

Rubin, I.

1978-01-01

Analytical tools, methods and techniques for assessing the design and performance of the space shuttle orbiter data processing system (DPS) are provided. The computer data processing network is evaluated in the key areas of queueing behavior synchronization and network reliability. The structure of the data processing network is described as well as the system operation principles and the network configuration. The characteristics of the computer systems are indicated. System reliability measures are defined and studied. System and network invulnerability measures are computed. Communication path and network failure analysis techniques are included.

A Phenomenological Research Study on Writer's Block: Causes, Processes, and Results

ERIC Educational Resources Information Center

Bastug, Muhammet; Ertem, Ihsan Seyit; Keskin, Hasan Kagan

2017-01-01

Purpose: The purpose of this paper is to investigate the causes, processes of writer's block experienced by a group of classroom teacher candidates and its impact on them. Design/methodology/approach: The phenomenological design, which is a qualitative research design, was preferred in the research since it was aimed to investigate the causes,…

Learning Effects of a Science Textbook Designed with Adapted Cognitive Process Principles on Grade 5 Students

ERIC Educational Resources Information Center

Cheng, Ming-Chang; Chou, Pei-I; Wang, Ya-Ting; Lin, Chih-Ho

2015-01-01

This study investigates how the illustrations in a science textbook, with their design modified according to cognitive process principles, affected students' learning performance. The quasi-experimental design recruited two Grade 5 groups (N?=?58) as the research participants. The treatment group (n?=?30) used the modified version of the textbook,…

Relating Right Brain Studies to the Design Process.

ERIC Educational Resources Information Center

Hofland, John

Intended for teachers of theatrical design who need to describe a design process for their students, this paper begins by giving a brief overview of recent research that has described the different functions of the right and left cerebral hemispheres. It then notes that although the left hemisphere tends to dominate the right hemisphere, it is the…

Malleable Thought: The Role of Craft Thinking in Practice-Led Graphic Design

ERIC Educational Resources Information Center

Ings, Welby

2015-01-01

This article considers the potential of craft processes as creative engagements in graphic design research. It initially discusses the uneasy history of craft within the discipline, then draws upon case studies undertaken by three established designers who, in their postgraduate theses, engaged with craft as a process of thinking. In doing so, the…

Novel ergonomic postural assessment method (NERPA) using product-process computer aided engineering for ergonomic workplace design.

PubMed

Sanchez-Lite, Alberto; Garcia, Manuel; Domingo, Rosario; Angel Sebastian, Miguel

2013-01-01

Musculoskeletal disorders (MSDs) that result from poor ergonomic design are one of the occupational disorders of greatest concern in the industrial sector. A key advantage in the primary design phase is to focus on a method of assessment that detects and evaluates the potential risks experienced by the operative when faced with these types of physical injuries. The method of assessment will improve the process design identifying potential ergonomic improvements from various design alternatives or activities undertaken as part of the cycle of continuous improvement throughout the differing phases of the product life cycle. This paper presents a novel postural assessment method (NERPA) fit for product-process design, which was developed with the help of a digital human model together with a 3D CAD tool, which is widely used in the aeronautic and automotive industries. The power of 3D visualization and the possibility of studying the actual assembly sequence in a virtual environment can allow the functional performance of the parts to be addressed. Such tools can also provide us with an ergonomic workstation design, together with a competitive advantage in the assembly process. The method developed was used in the design of six production lines, studying 240 manual assembly operations and improving 21 of them. This study demonstrated the proposed method's usefulness and found statistically significant differences in the evaluations of the proposed method and the widely used Rapid Upper Limb Assessment (RULA) method.

[Optimizing the extracting technique of ampelopsin from Ampelopsis cantoniensis Planch by a uniform design method].

PubMed

He, Zhi-feng; Zeng, Sa; Hou, Juan-juan; Liu, De-yu

2006-07-01

To optimize the preparation of ampelopsin from Ampelopsis Cantoniensis Planch. The extraction and purification process was studied by the uniform design with the extract of ampelopsin content and purity as markers. The facters which influence the extraction and the purification of ampelopsin content were studied by uniform design. The optimum extraction and purification process: the concentration for alcohol was 90%, and refluxing quartic, 1.5 h each time; extraction by petroleum ether quintic, the mount of active carbon was 1 g/100 g of the medicine material, and recrystaling thrice. This extraction process has higher yield of ampelopsin and is available for production.

Optimization of the Manufacturing Process of Conical Shell Structures Using Prepreg Laminatees

NASA Astrophysics Data System (ADS)

Khakimova, Regina; Zimmermann, Rolf; Burau, Florian; Siebert, Marc; Arbelo, Mariano; Castro, Saullo; Degenhardt, Richard

2014-06-01

The design and manufacture of an unstiffened composite conical structure which is a scaled-down version of the Ariane 5 Midlife Evolution Equipment Bay Structure is presented. For such benchmarking structures the fiber orientation error is critical and then the manufacturing process becomes a big challenge. The paper therefore is focused on the implementation of a tailoring study and on the manufacturing process. The conical structure will be tested to validate a new design approach.This study contributes to the European Union (EU) project DESICOS, whose aim is to develop less conservative design guidelines for imperfection sensitive thin-walled structures.

Optimisation study of a vehicle bumper subsystem with fuzzy parameters

NASA Astrophysics Data System (ADS)

Farkas, L.; Moens, D.; Donders, S.; Vandepitte, D.

2012-10-01

This paper deals with the design and optimisation for crashworthiness of a vehicle bumper subsystem, which is a key scenario for vehicle component design. The automotive manufacturers and suppliers have to find optimal design solutions for such subsystems that comply with the conflicting requirements of the regulatory bodies regarding functional performance (safety and repairability) and regarding the environmental impact (mass). For the bumper design challenge, an integrated methodology for multi-attribute design engineering of mechanical structures is set up. The integrated process captures the various tasks that are usually performed manually, this way facilitating the automated design iterations for optimisation. Subsequently, an optimisation process is applied that takes the effect of parametric uncertainties into account, such that the system level of failure possibility is acceptable. This optimisation process is referred to as possibility-based design optimisation and integrates the fuzzy FE analysis applied for the uncertainty treatment in crash simulations. This process is the counterpart of the reliability-based design optimisation used in a probabilistic context with statistically defined parameters (variabilities).

Risk assessment as standard work in design.

PubMed

Morrill, Patricia W

2013-01-01

This case study article examines a formal risk assessment as part of the decision making process for design solutions in high risk areas. The overview of the Failure Modes and Effects Analysis (FMEA) tool with examples of its application in hospital building projects will demonstrate the benefit of those structured conversations. This article illustrates how two hospitals used FMEA when integrating operational processes with building projects: (1) adjacency decision for Intensive Care Unit (ICU); and (2) distance concern for handling of specimens from Surgery to Lab. Both case studies involved interviews that exposed facility solution concerns. Just-in-time studies using the FMEA followed the same risk assessment process with the same workshop facilitator involving structured conversations in analyzing risks. In both cases, participants uncovered key areas of risk enabling them to take the necessary next steps. While the focus of this article is not the actual design solution, it is apparent that the risk assessment brought clarity to the situations resulting in prompt decision making about facility solutions. Hospitals are inherently risky environments; therefore, use of the formal risk assessment process, FMEA, is an opportunity for design professionals to apply more rigor to design decision making when facility solutions impact operations in high risk areas. Case study, decision making, hospital, infection control, strategy, work environment.

Promoting Teacher Adoption of GIS Using Teacher-Centered and Teacher-Friendly Design

ERIC Educational Resources Information Center

Hong, Jung Eun

2014-01-01

This article reports the results of a case study that employed user-centered design to develop training tutorials for helping middle school social studies teachers use Web-based GIS in their classrooms. This study placed teachers in the center of the design process in planning, designing, and developing the tutorials. This article describes how…

User Design: A Case Study on Corporate Change

ERIC Educational Resources Information Center

Pastore, Raymond S.; Carr-Chellman, Alison A.; Lohmann, Neal

2011-01-01

The purpose of this study was to examine the effects of implementing user design strategies within the corporate culture. Using a case study design approach, this article explores the change process within a "Fortune" 100 company in which users were given significant decision-making powers. The main focus is on the unique nature of user design in…

Innovation in Information Technology: Theoretical and Empirical Study in SMQR Section of Export Import in Automotive Industry

NASA Astrophysics Data System (ADS)

Edi Nugroho Soebandrija, Khristian; Pratama, Yogi

2014-03-01

This paper has the objective to provide the innovation in information technology in both theoretical and empirical study. Precisely, both aspects relate to the Shortage Mispacking Quality Report (SMQR) Claims in Export and Import in Automotive Industry. This paper discusses the major aspects of Innovation, Information Technology, Performance and Competitive Advantage. Furthermore, In the empirical study of PT. Astra Honda Motor (AHM) refers to SMQR Claims, Communication Systems, Analysis and Design Systems. Briefly both aspects of the major aspects and its empirical study are discussed in the Introduction Session. Furthermore, the more detail discussion is conducted in the related aspects in other sessions of this paper, in particular in Literature Review in term classical and updated reference of current research. The increases of SMQR claim and communication problem at PT. Astra Daihatsu Motor (PT. ADM) which still using the email cause the time of claim settlement become longer and finally it causes the rejected of SMQR claim by supplier. With presence of this problem then performed to design the integrated communication system to manage the communication process of SMQR claim between PT. ADM with supplier. The systems was analyzed and designed is expected to facilitate the claim communication process so that can be run in accordance with the procedure and fulfill the target of claim settlement time and also eliminate the difficulties and problems on the previous manual communication system with the email. The design process of the system using the approach of system development life cycle method by Kendall & Kendall (2006)which design process covers the SMQR problem communication process, judgment process by the supplier, claim process, claim payment process and claim monitoring process. After getting the appropriate system designs for managing the SMQR claim, furthermore performed the system implementation and can be seen the improvement in claim communication process and settlement time become faster and achieve the target. The conclusion in this paper comprises two major aspects. The first one refers to the conclusion in term of theory and concept. The second one refers to the conclusion in term of the empirical study of one of automotive industries in Indonesia. Both of them are expected to have contribution in current and future research of related aspects that are discussed in this paper.

Empowerment in the process of health messaging for rural low-income mothers: an exploratory message design project.

PubMed

Aldoory, Linda; Braun, Bonnie; Maring, Elisabeth Fost; Duggal, Mili; Briones, Rowena Lynn

2015-01-01

Rural, low-income mothers face challenges to their health equal to or greater than those of low-income mothers from urban areas. This study put health message design into the hands of low-income rural mothers. The current study filled a research gap by analyzing a participatory process used to design health messages tailored to the everyday lives of rural low-income mothers. A total of forty-three mothers participated in nine focus groups, which were held from 2012 to 2013, in eight states. The mothers were from different racial and ethnic backgrounds. Participants discussed food security, physical activity, and oral health information. They created messages by considering several elements: visuals, length of message, voice/perspective, self-efficacy and personal control, emotional appeals, positive and negative reinforcements, and steps to health behavior change. This study was innovative in its focus on empowerment as a key process to health message design.

An interdisciplinary team communication framework and its application to healthcare 'e-teams' systems design

PubMed Central

2009-01-01

Background There are few studies that examine the processes that interdisciplinary teams engage in and how we can design health information systems (HIS) to support those team processes. This was an exploratory study with two purposes: (1) To develop a framework for interdisciplinary team communication based on structures, processes and outcomes that were identified as having occurred during weekly team meetings. (2) To use the framework to guide 'e-teams' HIS design to support interdisciplinary team meeting communication. Methods An ethnographic approach was used to collect data on two interdisciplinary teams. Qualitative content analysis was used to analyze the data according to structures, processes and outcomes. Results We present details for team meta-concepts of structures, processes and outcomes and the concepts and sub concepts within each meta-concept. We also provide an exploratory framework for interdisciplinary team communication and describe how the framework can guide HIS design to support 'e-teams'. Conclusion The structures, processes and outcomes that describe interdisciplinary teams are complex and often occur in a non-linear fashion. Electronic data support, process facilitation and team video conferencing are three HIS tools that can enhance team function. PMID:19754966

An interdisciplinary team communication framework and its application to healthcare 'e-teams' systems design.

PubMed

Kuziemsky, Craig E; Borycki, Elizabeth M; Purkis, Mary Ellen; Black, Fraser; Boyle, Michael; Cloutier-Fisher, Denise; Fox, Lee Ann; MacKenzie, Patricia; Syme, Ann; Tschanz, Coby; Wainwright, Wendy; Wong, Helen

2009-09-15

There are few studies that examine the processes that interdisciplinary teams engage in and how we can design health information systems (HIS) to support those team processes. This was an exploratory study with two purposes: (1) To develop a framework for interdisciplinary team communication based on structures, processes and outcomes that were identified as having occurred during weekly team meetings. (2) To use the framework to guide 'e-teams' HIS design to support interdisciplinary team meeting communication. An ethnographic approach was used to collect data on two interdisciplinary teams. Qualitative content analysis was used to analyze the data according to structures, processes and outcomes. We present details for team meta-concepts of structures, processes and outcomes and the concepts and sub concepts within each meta-concept. We also provide an exploratory framework for interdisciplinary team communication and describe how the framework can guide HIS design to support 'e-teams'. The structures, processes and outcomes that describe interdisciplinary teams are complex and often occur in a non-linear fashion. Electronic data support, process facilitation and team video conferencing are three HIS tools that can enhance team function.

A quality-by-design approach to risk reduction and optimization for human embryonic stem cell cryopreservation processes.

PubMed

Mitchell, Peter D; Ratcliffe, Elizabeth; Hourd, Paul; Williams, David J; Thomas, Robert J

2014-12-01

It is well documented that cryopreservation and resuscitation of human embryonic stem cells (hESCs) is complex and ill-defined, and often suffers poor cell recovery and increased levels of undesirable cell differentiation. In this study we have applied Quality-by-Design (QbD) concepts to the critical processes of slow-freeze cryopreservation and resuscitation of hESC colony cultures. Optimized subprocesses were linked together to deliver a controlled complete process. We have demonstrated a rapid, high-throughput, and stable system for measurement of cell adherence and viability as robust markers of in-process and postrecovery cell state. We observed that measurement of adherence and viability of adhered cells at 1 h postseeding was predictive of cell proliferative ability up to 96 h in this system. Application of factorial design defined the operating spaces for cryopreservation and resuscitation, critically linking the performance of these two processes. Optimization of both processes resulted in enhanced reattachment and post-thaw viability, resulting in substantially greater recovery of cryopreserved, pluripotent cell colonies. This study demonstrates the importance of QbD concepts and tools for rapid, robust, and low-risk process design that can inform manufacturing controls and logistics.

Parametric Design within an Atomic Design Process (ADP) applied to Spacecraft Design

NASA Astrophysics Data System (ADS)

Ramos Alarcon, Rafael

This thesis describes research investigating the development of a model for the initial design of complex systems, with application to spacecraft design. The design model is called an atomic design process (ADP) and contains four fundamental stages (specifications, configurations, trade studies and drivers) that constitute the minimum steps of an iterative process that helps designers find a feasible solution. Representative design models from the aerospace industry are reviewed and are compared with the proposed model. The design model's relevance, adaptability and scalability features are evaluated through a focused design task exercise with two undergraduate teams and a long-term design exercise performed by a spacecraft payload team. The implementation of the design model is explained in the context in which the model has been researched. This context includes the organization (a student-run research laboratory at the University of Michigan), its culture (academically oriented), members that have used the design model and the description of the information technology elements meant to provide support while using the model. This support includes a custom-built information management system that consolidates relevant information that is currently being used in the organization. The information is divided in three domains: personnel development history, technical knowledge base and laboratory operations. The focused study with teams making use of the design model to complete an engineering design exercise consists of the conceptual design of an autonomous system, including a carrier and a deployable lander that form the payload of a rocket with an altitude range of over 1000 meters. Detailed results from each of the stages of the design process while implementing the model are presented, and an increase in awareness of good design practices in the teams while using the model are explained. A long-term investigation using the design model consisting of the successful characterization of an imaging system for a spacecraft is presented. The spacecraft is designed to take digital color images from low Earth orbit. The dominant drivers from each stage of the design process are indicated as they were identified, with the accompanying hardware development leading to the final configuration that comprises the flight spacecraft.

Education Leaders' Decision-Making Processes about Educational Facilities in a University Multiple Stakeholder Environment

ERIC Educational Resources Information Center

Kelting, Scott

2011-01-01

This research is a retrospective case study designed to document and analyze the process of decision-making by educational leaders and stakeholders at a four-year university. For this study, educational leaders and key stakeholders agreed to extensive interviews about the decisions made during the design, construction, and post-occupancy phases of…

Reliability of the Nursing Home Survey Process: A Simultaneous Survey Approach

ERIC Educational Resources Information Center

Lee, Robert H.; Gajewski, Byron J.; Thompson, Sarah

2006-01-01

Purpose: We designed this study to examine the reliability of the nursing home survey process in the state of Kansas using regular and simultaneous survey teams. In particular, the study examined how two survey teams exposed to the same information at the same time differed in their interpretations. Design and Methods: The protocol for…

Model of Values-Based Management Process in Schools: A Mixed Design Study

ERIC Educational Resources Information Center

Dogan, Soner

2016-01-01

The aim of this paper is to evaluate the school administrators' values-based management behaviours according to the teachers' perceptions and opinions and, accordingly, to build a model of values-based management process in schools. The study was conducted using explanatory design which is inclusive of both quantitative and qualitative methods.…

Studying Implementation within a Continuous Continuous-Improvement Process: What Happens When We Design with Adaptations in Mind?

ERIC Educational Resources Information Center

Tichnor-Wagner, Ariel; Allen, Danielle; Socol, Allison Rose; Cohen-Vogel, Lora; Rutledge, Stacey A.; Xing, Qi W.

2018-01-01

Background/Context: This study examines the implementation of an academic and social-emotional learning innovation called Personalization for Academic and Social-Emotional Learning, or PASL. The innovation was designed, tested, and implemented using a continuous continuous-improvement model. The model emphasized a top-and-bottom process in which…

A Case Study of Professors' and Instructional Designers' Experiences in the Development of Online Courses

ERIC Educational Resources Information Center

Stevens, Karl B.

2012-01-01

The purpose of this qualitative case study was to examine the experiences of instructional designers and professors during the online course development process and to determine if their experiences had an effect on the process itself. To gain an understanding of their experiences, open-ended interviews were conducted, seeking descriptions of…

Phase A design study of microgravity fluoride fiber puller

NASA Technical Reports Server (NTRS)

Workman, Gary L.; Smith, Guy A.; Kosten, Susan

1994-01-01

Improved transmission properties for fluoride fibers due to space processing has great potential for commercial benefits. Phase A design study will determine conceptual feasibility and provide initial definition of the technical requirements and design issues for space.

Who Gets Designated a Terrorist and Why?

ERIC Educational Resources Information Center

Beck, Colin J.; Miner, Emily

2013-01-01

This study examines formal terrorism designations by governments through the lens of organization studies research on categorization processes. It is argued that designations hinge on markers from the organizational profile of a militant group. Using cross-sectional data on militant organizations and designations by the United States, the United…

How work context affects operating room processes: using data mining and computer simulation to analyze facility and process design.

PubMed

Baumgart, André; Denz, Christof; Bender, Hans-Joachim; Schleppers, Alexander

2009-01-01

The complexity of the operating room (OR) requires that both structural (eg, department layout) and behavioral (eg, staff interactions) patterns of work be considered when developing quality improvement strategies. In our study, we investigated how these contextual factors influence outpatient OR processes and the quality of care delivered. The study setting was a German university-affiliated hospital performing approximately 6000 outpatient surgeries annually. During the 3-year-study period, the hospital significantly changed its outpatient OR facility layout from a decentralized (ie, ORs in adjacent areas of the building) to a centralized (ie, ORs in immediate vicinity of each other) design. To study the impact of the facility change on OR processes, we used a mixed methods approach, including process analysis, process modeling, and social network analysis of staff interactions. The change in facility layout was seen to influence OR processes in ways that could substantially affect patient outcomes. For example, we found a potential for more errors during handovers in the new centralized design due to greater interdependency between tasks and staff. Utilization of the mixed methods approach in our analysis, as compared with that of a single assessment method, enabled a deeper understanding of the OR work context and its influence on outpatient OR processes.

The Development of a Design and Construction Process Protocol to Support the Home Modification Process Delivered by Occupational Therapists

PubMed Central

Ormerod, Marcus; Newton, Rita

2018-01-01

Modifying the home environments of older people as they age in place is a well-established health and social care intervention. Using design and construction methods to redress any imbalance caused by the ageing process or disability within the home environment, occupational therapists are seen as the experts in this field of practice. However, the process used by occupational therapists when modifying home environments has been criticised for being disorganised and not founded on theoretical principles and concepts underpinning the profession. To address this issue, research was conducted to develop a design and construction process protocol specifically for home modifications. A three-stage approach was taken for the analysis of qualitative data generated from an online survey, completed by 135 occupational therapists in the UK. Using both the existing occupational therapy intervention process model and the design and construction process protocol as the theoretical frameworks, a 4-phase, 9-subphase design and construction process protocol for home modifications was developed. Overall, the study is innovative in developing the first process protocol for home modifications, potentially providing occupational therapists with a systematic and effective approach to the design and delivery of home modification services for older and disabled people. PMID:29682348

The Development of a Design and Construction Process Protocol to Support the Home Modification Process Delivered by Occupational Therapists.

PubMed

Russell, Rachel; Ormerod, Marcus; Newton, Rita

2018-01-01

Modifying the home environments of older people as they age in place is a well-established health and social care intervention. Using design and construction methods to redress any imbalance caused by the ageing process or disability within the home environment, occupational therapists are seen as the experts in this field of practice. However, the process used by occupational therapists when modifying home environments has been criticised for being disorganised and not founded on theoretical principles and concepts underpinning the profession. To address this issue, research was conducted to develop a design and construction process protocol specifically for home modifications. A three-stage approach was taken for the analysis of qualitative data generated from an online survey, completed by 135 occupational therapists in the UK. Using both the existing occupational therapy intervention process model and the design and construction process protocol as the theoretical frameworks, a 4-phase, 9-subphase design and construction process protocol for home modifications was developed. Overall, the study is innovative in developing the first process protocol for home modifications, potentially providing occupational therapists with a systematic and effective approach to the design and delivery of home modification services for older and disabled people.

Reengineering a database for clinical trials management: lessons for system architects.

PubMed

Brandt, C A; Nadkarni, P; Marenco, L; Karras, B T; Lu, C; Schacter, L; Fisk, J M; Miller, P L

2000-10-01

This paper describes the process of enhancing Trial/DB, a database system for clinical studies management. The system's enhancements have been driven by the need to maximize the effectiveness of developer personnel in supporting numerous and diverse users, of study designers in setting up new studies, and of administrators in managing ongoing studies. Trial/DB was originally designed to work over a local area network within a single institution, and basic architectural changes were necessary to make it work over the Internet efficiently as well as securely. Further, as its use spread to diverse communities of users, changes were made to let the processes of study design and project management adapt to the working styles of the principal investigators and administrators for each study. The lessons learned in the process should prove instructive for system architects as well as managers of electronic patient record systems.

Identification of Tools and Techniques to Enhance Interdisciplinary Collaboration During Design and Construction Projects.

PubMed

Keys, Yolanda; Silverman, Susan R; Evans, Jennie

2017-10-01

The purpose of this study was to collect the perceptions of design professionals and clinicians regarding design process success strategies and elements of interprofessional engagement and communication during healthcare design and construction projects. Additional objectives were to gather best practices to maximize clinician engagement and provide tools and techniques to improve interdisciplinary collaboration for future projects. Strategies are needed to enhance the design and construction process and create interactions that benefit not only the project but the individuals working to see its completion. Meaningful interprofessional collaboration is essential to any healthcare design project and making sure the various players communicate is a critical element. This was a qualitative study conducted via an online survey. Respondents included architects, construction managers, interior designers, and healthcare personnel who had recently been involved in a building renovation or new construction project for a healthcare facility. Responses to open-ended questions were analyzed for themes, and descriptive statistics were used to provide insight into participant demographics. Information on the impressions, perceptions, and opportunities related to clinician involvement in design projects was collected from nurses, architects, interior designers, and construction managers. Qualitative analysis revealed themes of clinician input, organizational dynamics, and a variety of communication strategies to be the most frequently mentioned elements of successful interprofessional collaboration. This study validates the need to include clinician input in the design process, to consider the importance of organizational dynamics on design team functioning, and to incorporate effective communication strategies during design and construction projects.

A quality by design study applied to an industrial pharmaceutical fluid bed granulation.

PubMed

Lourenço, Vera; Lochmann, Dirk; Reich, Gabriele; Menezes, José C; Herdling, Thorsten; Schewitz, Jens

2012-06-01

The pharmaceutical industry is encouraged within Quality by Design (QbD) to apply science-based manufacturing principles to assure quality not only of new but also of existing processes. This paper presents how QbD principles can be applied to an existing industrial pharmaceutical fluid bed granulation (FBG) process. A three-step approach is presented as follows: (1) implementation of Process Analytical Technology (PAT) monitoring tools at the industrial scale process, combined with multivariate data analysis (MVDA) of process and PAT data to increase the process knowledge; (2) execution of scaled-down designed experiments at a pilot scale, with adequate PAT monitoring tools, to investigate the process response to intended changes in Critical Process Parameters (CPPs); and finally (3) the definition of a process Design Space (DS) linking CPPs to Critical to Quality Attributes (CQAs), within which product quality is ensured by design, and after scale-up enabling its use at the industrial process scale. The proposed approach was developed for an existing industrial process. Through enhanced process knowledge established a significant reduction in product CQAs, variability already within quality specifications ranges was achieved by a better choice of CPPs values. The results of such step-wise development and implementation are described. Copyright © 2012 Elsevier B.V. All rights reserved.

Design requirements for operational earth resources ground data processing

NASA Technical Reports Server (NTRS)

Baldwin, C. J.; Bradford, L. H.; Burnett, E. S.; Hutson, D. E.; Kinsler, B. A.; Kugle, D. R.; Webber, D. S.

1972-01-01

Realistic tradeoff data and evaluation techniques were studied that permit conceptual design of operational earth resources ground processing systems. Methodology for determining user requirements that utilize the limited information available from users is presented along with definitions of sensor capabilities projected into the shuttle/station era. A tentative method is presented for synthesizing candidate ground processing concepts.

DESIGNING EFFICIENT, ECONOMIC AND ENVIRONMENTALLY FRIENDLY CHEMICAL PROCESSES

EPA Science Inventory

A catalytic reforming process has been studied using hierarchical design and simulation calculations. Approximations for the fugitive emissions indicate which streams allow the most value to be lost and which have the highest potential environmental impact. One can use this infor...

DESIGNING EFFICIENT, ECONOMIC AND ENVIRONMENTALLY FRIENDLY CHEMICAL PROCESSES

EPA Science Inventory

A catalytic reforming process has been studied using hierarchical design and simulation calculations. Aproximations for the fugitive emissions indicate which streams allow the most value to be lost and which have the highest potential environmental impact. One can use tis inform...

Simulation models and designs for advanced Fischer-Tropsch technology

DOE Office of Scientific and Technical Information (OSTI.GOV)

Choi, G.N.; Kramer, S.J.; Tam, S.S.

1995-12-31

Process designs and economics were developed for three grass-roots indirect Fischer-Tropsch coal liquefaction facilities. A baseline and an alternate upgrading design were developed for a mine-mouth plant located in southern Illinois using Illinois No. 6 coal, and one for a mine-mouth plane located in Wyoming using Power River Basin coal. The alternate design used close-coupled ZSM-5 reactors to upgrade the vapor stream leaving the Fischer-Tropsch reactor. ASPEN process simulation models were developed for all three designs. These results have been reported previously. In this study, the ASPEN process simulation model was enhanced to improve the vapor/liquid equilibrium calculations for themore » products leaving the slurry bed Fischer-Tropsch reactors. This significantly improved the predictions for the alternate ZSM-5 upgrading design. Another model was developed for the Wyoming coal case using ZSM-5 upgrading of the Fischer-Tropsch reactor vapors. To date, this is the best indirect coal liquefaction case. Sensitivity studies showed that additional cost reductions are possible.« less

Ultra-processed Food Intake and Obesity: What Really Matters for Health-Processing or Nutrient Content?

PubMed

Poti, Jennifer M; Braga, Bianca; Qin, Bo

2017-12-01

The aim of this narrative review was to summarize and critique recent evidence evaluating the association between ultra-processed food intake and obesity. Four of five studies found that higher purchases or consumption of ultra-processed food was associated with overweight/obesity. Additional studies reported relationships between ultra-processed food intake and higher fasting glucose, metabolic syndrome, increases in total and LDL cholesterol, and risk of hypertension. It remains unclear whether associations can be attributed to processing itself or the nutrient content of ultra-processed foods. Only three of nine studies used a prospective design, and the potential for residual confounding was high. Recent research provides fairly consistent support for the association of ultra-processed food intake with obesity and related cardiometabolic outcomes. There is a clear need for further studies, particularly those using longitudinal designs and with sufficient control for confounding, to potentially confirm these findings in different populations and to determine whether ultra-processed food consumption is associated with obesity independent of nutrient content.

Riser Feeding Evaluation Method for Metal Castings Using Numerical Analysis

NASA Astrophysics Data System (ADS)

Ahmad, Nadiah

One of the design aspects that continues to create a challenge for casting designers is the optimum design of casting feeders (risers). As liquid metal solidifies, the metal shrinks and forms cavities inside the casting. In order to avoid shrinkage cavities, risers are added to the casting shape to supply additional molten metal when shrinkage occurs during solidification. The shrinkage cavities in the casting are compensated by controlling the cooling rate to promote directional solidification. This control can be achieved by designing the casting such that the cooling begins at the sections that are farthest away from the risers and ends at the risers. Therefore, the risers will solidify last and feed the casting with the molten metal. As a result, the shrinkage cavities formed during solidification are in the risers which are later removed from the casting. Since casting designers have to usually go through iterative processes of validating the casting designs which are very costly due to expensive simulation processes or manual trials and errors on actual casting processes, this study investigates more efficient methods that will help casting designers utilize their casting experiences systematically to develop good initial casting designs. The objective is to reduce the casting design method iterations; therefore, reducing the cost involved in that design processes. The aim of this research aims at finding a method that can help casting designers design effective risers used in sand casting process of aluminum-silicon alloys by utilizing the analysis of solidification simulation. The analysis focuses on studying the significance of pressure distribution of the liquid metal at the early stage of casting solidification, when heat transfer and convective fluid flow are taken into account in the solidification simulation. The mathematical model of casting solidification was solved using the finite volume method (FVM). This study focuses to improve our understanding of the feeding behavior in aluminum-silicon alloys and the effective feeding by considering the pressure gradient distribution of the molten metal at casting dendrite coherency point. For this study, we will identify the relationship between feeding efficiency, shrinkage behavior and how the change in riser size affects the pressure gradient in the casting. This understanding will be used to help in the design of effective risers.

Application of quality by design principles to the development and technology transfer of a major process improvement for the manufacture of a recombinant protein.

PubMed

Looby, Mairead; Ibarra, Neysi; Pierce, James J; Buckley, Kevin; O'Donovan, Eimear; Heenan, Mary; Moran, Enda; Farid, Suzanne S; Baganz, Frank

2011-01-01

This study describes the application of quality by design (QbD) principles to the development and implementation of a major manufacturing process improvement for a commercially distributed therapeutic protein produced in Chinese hamster ovary cell culture. The intent of this article is to focus on QbD concepts, and provide guidance and understanding on how the various components combine together to deliver a robust process in keeping with the principles of QbD. A fed-batch production culture and a virus inactivation step are described as representative examples of upstream and downstream unit operations that were characterized. A systematic approach incorporating QbD principles was applied to both unit operations, involving risk assessment of potential process failure points, small-scale model qualification, design and execution of experiments, definition of operating parameter ranges and process validation acceptance criteria followed by manufacturing-scale implementation and process validation. Statistical experimental designs were applied to the execution of process characterization studies evaluating the impact of operating parameters on product quality attributes and process performance parameters. Data from process characterization experiments were used to define the proven acceptable range and classification of operating parameters for each unit operation. Analysis of variance and Monte Carlo simulation methods were used to assess the appropriateness of process design spaces. Successful implementation and validation of the process in the manufacturing facility and the subsequent manufacture of hundreds of batches of this therapeutic protein verifies the approaches taken as a suitable model for the development, scale-up and operation of any biopharmaceutical manufacturing process. Copyright © 2011 American Institute of Chemical Engineers (AIChE).

Designing a ticket to ride with the Cognitive Work Analysis Design Toolkit.

PubMed

Read, Gemma J M; Salmon, Paul M; Lenné, Michael G; Jenkins, Daniel P

2015-01-01

Cognitive work analysis has been applied in the design of numerous sociotechnical systems. The process used to translate analysis outputs into design concepts, however, is not always clear. Moreover, structured processes for translating the outputs of ergonomics methods into concrete designs are lacking. This paper introduces the Cognitive Work Analysis Design Toolkit (CWA-DT), a design approach which has been developed specifically to provide a structured means of incorporating cognitive work analysis outputs in design using design principles and values derived from sociotechnical systems theory. This paper outlines the CWA-DT and describes its application in a public transport ticketing design case study. Qualitative and quantitative evaluations of the process provide promising early evidence that the toolkit fulfils the evaluation criteria identified for its success, with opportunities for improvement also highlighted. The Cognitive Work Analysis Design Toolkit has been developed to provide ergonomics practitioners with a structured approach for translating the outputs of cognitive work analysis into design solutions. This paper demonstrates an application of the toolkit and provides evaluation findings.

Crucial design issues for special access technology; a Delphi study.

PubMed

O'Rourke, Pearl; Ekins, Ray; Timmins, Bernard; Timmins, Fiona; Long, Siobhan; Coyle, Eugene

2014-01-01

To develop and demonstrate a method to involve professional users of assistive technology (AT) in the development process of customisable products. Employing the ideas of user participation and mass customisation, this research addresses the need for reduced product costs and optimised product flexibility. An adaptable six-question Delphi study was developed to establish consensus among AT professionals on design issues relating to a specified AT domain requiring innovation. The study is demonstrated for the special access technology (SAT) domain. A modified morphological matrix structures the application of the study results to the product design process. Fourteen professionals from the Republic of Ireland and the UK participated. Consensus was reached on prevalent parts of SAT that malfunction, primary reasons for SAT malfunction, characteristics of clients associated with SAT selection, client needs regarding SAT use and training, desirable traits of SAT and clinicians' frustrations with SAT. The study revealed a range of problems related to SAT, highlighting the complexities of successful SAT adoption. The questions led to differentiated insights and enabled design solution conceptualisation from various perspectives. The approach was found to help facilitate efficient generation and application of professional users' knowledge during the design process of customisable AT.

The LITERACY-Portal as the Subject of a Case Study on a Human-Centered Design Solution Supporting Users with Special Needs

ERIC Educational Resources Information Center

Hagelkruys, Dominik; Motschnig, Renate

2017-01-01

Case studies help to reflect and to capture information about complex processes and domains and to make it reusable for future application in related contexts. In the case study reported in this article, we aim to capture and share processes and experience that we gained while designing a web-portal for supporting the specific user group of…

Learning Theory Expertise in the Design of Learning Spaces: Who Needs a Seat at the Table?

ERIC Educational Resources Information Center

Rook, Michael M.; Choi, Koun; McDonald, Scott P.

2015-01-01

This study highlights the impact of including stakeholders with expertise in learning theory in a learning space design process. We present the decision-making process during the design of the Krause Innovation Studio on the campus of the Pennsylvania State University to draw a distinction between the architect and faculty member's decision-making…

Providing Guidance in Virtual Lab Experimentation: The Case of an Experiment Design Tool

ERIC Educational Resources Information Center

Efstathiou, Charalampos; Hovardas, Tasos; Xenofontos, Nikoletta A.; Zacharia, Zacharias C.; deJong, Ton; Anjewierden, Anjo; van Riesen, Siswa A. N.

2018-01-01

The present study employed a quasi-experimental design to assess a computer-based tool, which was intended to scaffold the task of designing experiments when using a virtual lab for the process of experimentation. In particular, we assessed the impact of this tool on primary school students' cognitive processes and inquiry skills before and after…

An Exploratory Study of the Effect of Enclosed Structure on Type Design with Fixation Dispersion: Evidence from Eye Movements

ERIC Educational Resources Information Center

Ma, Min-Yuan; Chuang, Hsien-Chih

2017-01-01

Type design is the process of re-organizing visual elements and their corresponding meanings into a new organic entity, particularly for the highly logographic Chinese characters whose intrinsic features are retained even after re-organization. Due to this advantage, designers believe that such a re-organization process will not affect Chinese…

Creative user-centered visualization design for energy analysts and modelers.

PubMed

Goodwin, Sarah; Dykes, Jason; Jones, Sara; Dillingham, Iain; Dove, Graham; Duffy, Alison; Kachkaev, Alexander; Slingsby, Aidan; Wood, Jo

2013-12-01

We enhance a user-centered design process with techniques that deliberately promote creativity to identify opportunities for the visualization of data generated by a major energy supplier. Visualization prototypes developed in this way prove effective in a situation whereby data sets are largely unknown and requirements open - enabling successful exploration of possibilities for visualization in Smart Home data analysis. The process gives rise to novel designs and design metaphors including data sculpting. It suggests: that the deliberate use of creativity techniques with data stakeholders is likely to contribute to successful, novel and effective solutions; that being explicit about creativity may contribute to designers developing creative solutions; that using creativity techniques early in the design process may result in a creative approach persisting throughout the process. The work constitutes the first systematic visualization design for a data rich source that will be increasingly important to energy suppliers and consumers as Smart Meter technology is widely deployed. It is novel in explicitly employing creativity techniques at the requirements stage of visualization design and development, paving the way for further use and study of creativity methods in visualization design.

Role of System Architecture in Architecture in Developing New Drafting Tools

NASA Astrophysics Data System (ADS)

Sorguç, Arzu Gönenç

In this study, the impact of information technologies in architectural design process is discussed. In this discussion, first the differences/nuances between the concept of software engineering and system architecture are clarified. Then, the design process in engineering, and design process in architecture has been compared by considering 3-D models as the center of design process over which the other disciplines involve the design. It is pointed out that in many high-end engineering applications, 3-D solid models and consequently digital mock-up concept has become a common practice. But, architecture as one of the important customers of CAD systems employing these tools has not started to use these 3-D models. It is shown that the reason of this time lag between architecture and engineering lies behind the tradition of design attitude. Therefore, it is proposed a new design scheme a meta-model to develop an integrated design model being centered on 3-D model. It is also proposed a system architecture to achieve the transformation of architectural design process by replacing 2-D thinking with 3-D thinking. It is stated that in the proposed system architecture, the CAD systems are included and adapted for 3-D architectural design in order to provide interfaces for integration of all possible disciplines to design process. It is also shown that such a change will allow to elaborate the intelligent or smart building concept in future.

Implementation of quality by design approach in manufacturing process optimization of dry granulated, immediate release, coated tablets - a case study.

PubMed

Teżyk, Michał; Jakubowska, Emilia; Milanowski, Bartłomiej; Lulek, Janina

2017-10-01

The aim of this study was to optimize the process of tablets compression and identification of film-coating critical process parameters (CPPs) affecting critical quality attributes (CQAs) using quality by design (QbD) approach. Design of experiment (DOE) and regression methods were employed to investigate hardness, disintegration time, and thickness of uncoated tablets depending on slugging and tableting compression force (CPPs). Plackett-Burman experimental design was applied to identify critical coating process parameters among selected ones that is: drying and preheating time, atomization air pressure, spray rate, air volume, inlet air temperature, and drum pressure that may influence the hardness and disintegration time of coated tablets. As a result of the research, design space was established to facilitate an in-depth understanding of existing relationship between CPPs and CQAs of intermediate product (uncoated tablets). Screening revealed that spray rate and inlet air temperature are two most important factors that affect the hardness of coated tablets. Simultaneously, none of the tested coating factors have influence on disintegration time. The observation was confirmed by conducting film coating of pilot size batches.

Investigation on the Flexural Creep Stiffness Behavior of PC-ABS Material Processed by Fused Deposition Modeling Using Response Surface Definitive Screening Design

NASA Astrophysics Data System (ADS)

Mohamed, Omar Ahmed; Masood, Syed Hasan; Bhowmik, Jahar Lal

2017-03-01

The resistance of polymeric materials to time-dependent plastic deformation is an important requirement of the fused deposition modeling (FDM) design process, its processed products, and their application for long-term loading, durability, and reliability. The creep performance of the material and part processed by FDM is the fundamental criterion for many applications with strict dimensional stability requirements, including medical implants, electrical and electronic products, and various automotive applications. Herein, the effect of FDM fabrication conditions on the flexural creep stiffness behavior of polycarbonate-acrylonitrile-butadiene-styrene processed parts was investigated. A relatively new class of experimental design called "definitive screening design" was adopted for this investigation. The effects of process variables on flexural creep stiffness behavior were monitored, and the best suited quadratic polynomial model with high coefficient of determination ( R 2) value was developed. This study highlights the value of response surface definitive screening design in optimizing properties for the products and materials, and it demonstrates its role and potential application in material processing and additive manufacturing.

Process simulation during the design process makes the difference: process simulations applied to a traditional design.

PubMed

Traversari, Roberto; Goedhart, Rien; Schraagen, Jan Maarten

2013-01-01

The objective is evaluation of a traditionally designed operating room using simulation of various surgical workflows. A literature search showed that there is no evidence for an optimal operating room layout regarding the position and size of an ultraclean ventilation (UCV) canopy with a separate preparation room for laying out instruments and in which patients are induced in the operating room itself. Neither was literature found reporting on process simulation being used for this application. Many technical guidelines and designs have mainly evolved over time, and there is no evidence on whether the proposed measures are also effective for the optimization of the layout for workflows. The study was conducted by applying observational techniques to simulated typical surgical procedures. Process simulations which included complete surgical teams and equipment required for the intervention were carried out for four typical interventions. Four observers used a form to record conflicts with the clean area boundaries and the height of the supply bridge. Preferences for particular layouts were discussed with the surgical team after each simulated procedure. We established that a clean area measuring 3 × 3 m and a supply bridge height of 2.05 m was satisfactory for most situations, provided a movable operation table is used. The only cases in which conflicts with the supply bridge were observed were during the use of a surgical robot (Da Vinci) and a surgical microscope. During multiple trauma interventions, bottlenecks regarding the dimensions of the clean area will probably arise. The process simulation of four typical interventions has led to significantly different operating room layouts than were arrived at through the traditional design process. Evidence-based design, human factors, work environment, operating room, traditional design, process simulation, surgical workflowsPreferred Citation: Traversari, R., Goedhart, R., & Schraagen, J. M. (2013). Process simulation during the design process makes the difference: Process simulations applied to a traditional design. Health Environments Research & Design Journal 6(2), pp 58-76.

Using the Science Process Skills to Investigate Animals and Animal Habitats

NASA Astrophysics Data System (ADS)

Braithwaite, Saisha

This study explored how a STEM (science, technology, engineering, and math) engineer design challenge allowed students to analyze the characteristics of animals and animal habitats. This study was conducted in a kindergarten class within an urban school district. The class has 25 students while the study focuses on six students. The group consists of three boys and three girls. In this study, the students used the science process skills to observe, classify, infer, and make predictions about animals and habitats. In the engineer design, students created an established habitat and built their own animal that can survive in that habitat. The study analyzed how students used process skills to engage with the habitats and animals. The students successfully used the science process skills in this study. The results showed that students gained more content knowledge when they used multiple process skills within a lesson. The study shows that developing lessons using the science process skills improves students' ability to demonstrate their knowledge of animals and their habitats.

Development of an Instrument for the Measurement of Leadership Commitment to Organizational Process

ERIC Educational Resources Information Center

Hylton, Peter D.

2013-01-01

The purpose of this research study was to create a new instrument designed to examine the commitment of an organization's leadership to following organizational processes, as measured by stakeholder perceptions. This instrument was designed to aid in closure of a gap in the field of leadership studies relative to the impact that a leader's…

Guiding the Design of Lessons by Using the MAPLET Framework: Matching Aims, Processes, Learner Expertise and Technologies

ERIC Educational Resources Information Center

Ifenthaler, Dirk; Gosper, Maree

2014-01-01

This paper introduces the MAPLET framework that was developed to map and link teaching aims, learning processes, learner expertise and technologies. An experimental study with 65 participants is reported to test the effectiveness of the framework as a guide to the design of lessons embedded within larger units of study. The findings indicate the…

DESIGNING ENVIRONMENTALLY FRIENDLY CHEMICAL PROCESSES

EPA Science Inventory

The design of a chemical process involves many aspects: from profitability, flexibility and reliability to safety to the environment. While each of these is important, in this work, the focus will be on profitability and the environment. Key to the study of these aspects is the ...

Hybrid receiver study

NASA Technical Reports Server (NTRS)

Stone, M. S.; Mcadam, P. L.; Saunders, O. W.

1977-01-01

The results are presented of a 4 month study to design a hybrid analog/digital receiver for outer planet mission probe communication links. The scope of this study includes functional design of the receiver; comparisons between analog and digital processing; hardware tradeoffs for key components including frequency generators, A/D converters, and digital processors; development and simulation of the processing algorithms for acquisition, tracking, and demodulation; and detailed design of the receiver in order to determine its size, weight, power, reliability, and radiation hardness. In addition, an evaluation was made of the receiver's capabilities to perform accurate measurement of signal strength and frequency for radio science missions.

Using a contextualized sensemaking model for interaction design: A case study of tumor contouring.

PubMed

Aselmaa, Anet; van Herk, Marcel; Laprie, Anne; Nestle, Ursula; Götz, Irina; Wiedenmann, Nicole; Schimek-Jasch, Tanja; Picaud, Francois; Syrykh, Charlotte; Cagetti, Leonel V; Jolnerovski, Maria; Song, Yu; Goossens, Richard H M

2017-01-01

Sensemaking theories help designers understand the cognitive processes of a user when he/she performs a complicated task. This paper introduces a two-step approach of incorporating sensemaking support within the design of health information systems by: (1) modeling the sensemaking process of physicians while performing a task, and (2) identifying software interaction design requirements that support sensemaking based on this model. The two-step approach is presented based on a case study of the tumor contouring clinical task for radiotherapy planning. In the first step of the approach, a contextualized sensemaking model was developed to describe the sensemaking process based on the goal, the workflow and the context of the task. In the second step, based on a research software prototype, an experiment was conducted where three contouring tasks were performed by eight physicians respectively. Four types of navigation interactions and five types of interaction sequence patterns were identified by analyzing the gathered interaction log data from those twenty-four cases. Further in-depth study on each of the navigation interactions and interaction sequence patterns in relation to the contextualized sensemaking model revealed five main areas for design improvements to increase sensemaking support. Outcomes of the case study indicate that the proposed two-step approach was beneficial for gaining a deeper understanding of the sensemaking process during the task, as well as for identifying design requirements for better sensemaking support. Copyright © 2016. Published by Elsevier Inc.

Collective Design of an E-Textbook: Teachers' Collective Documentation

ERIC Educational Resources Information Center

Gueudet, Ghislaine; Pepin, Birgit; Sabra, Hussein; Trouche, Luc

2016-01-01

In this study, we investigated design processes in teacher collectives, which have been made possible by new "digital" opportunities: platforms, discussion lists, etc. The object of our study is the French Sésamath teacher association and its design of a grade 10 e-textbook, more precisely the design of the "functions" chapter.…

Volatile Organic Compound and Particulate Emission Studies of AF (Air Force) Paint Booth Facilities. Phase 1.

DTIC Science & Technology

1988-07-01

quantity of air which requires processing. Recirculation systems were designed for two of the painting facilities included in this study. In designing the...BACKGROUND AND PURPOSE .... ................ .... 57 B. DESIGN CONSIDERATIONS .... ............... .... 58 1. Safety Standards .......... ............... 58...65 5. Conceptual Design .... ................ ... 68 V CONCLUSIONS AND RECOMMENDATIONS ............... .. 72 A. CONCLUSIONS

[The Munich Attachment and Effectiveness Study: Study Design and a Case Example].

PubMed

Hörz-Sagstetter, Susanne; Minow, Anna-Rahel; Erhardt, Ingrid; Barten-Hohn, Julia; Denscherz, Claudia; Buchheim, Anna; Taubner, Svenja; Mertens, Wolfgang

2016-03-01

The "Munich Attachment and Effectiveness Study" is a prospective psychotherapy study examining process and outcome of psychoanalytic psychotherapies. The study design and results are exemplified in a single case. At 6 points in time audio-taped and transcribed therapy sessions are evaluated using process instruments (e. g. Psychotherapy Process Q-Set PQS) and interviews (e. g. Operationalized Psychodynamic Diagnostics OPD, Heidelberg Structural Change Scale HSCS, Adult Attachment Interview AAI). In the single case, findings from the psychotherapeutic process (e. g. "therapist is empathic" according to PQS) complement the achieved changes. 5 HSCS problem foci reached level of "restructuring", on the Reflective Functioning Scale a marked change of RF took place and the attachment classification changed over time. The instruments employed in this study corresponded well in assessing change processes in spite of differing theoretical background. © Georg Thieme Verlag KG Stuttgart · New York.

Designing for Diverse Learning: Case Study of Place-Based Learning in Design and Technologies Pre-Service Teacher Education

ERIC Educational Resources Information Center

Best, Marnie; MacGregor, Denise; Price, Deborah

2017-01-01

Place-based learning experiences in Design and Technologies education connect people and place with design processes and products. Drawing on place-based learning, this case study shares the experiences of eight final year pre-service Design and Technologies education students from the University of South Australia as they collaborated with…

Sustainable supply chain design: a configurational approach.

PubMed

Masoumik, S Maryam; Abdul-Rashid, Salwa Hanim; Olugu, Ezutah Udoncy; Raja Ghazilla, Raja Ariffin

2014-01-01

Designing the right supply chain that meets the requirements of sustainable development is a significant challenge. Although there are a considerable number of studies on issues relating to sustainable supply chain design (SSCD) in terms of designing the practices, processes, and structures, they have rarely demonstrated how these components can be aligned to form an effective sustainable supply chain (SSC). Considering this gap in the literature, this study adopts the configurational approach to develop a conceptual framework that could configure the components of a SSC. In this respect, a process-oriented approach is utilized to classify and harmonize the design components. A natural-resource-based view (NRBV) is adopted to determine the central theme to align the design components around. The proposed framework presents three types of SSC, namely, efficient SSC, innovative SSC, and reputed SSC. The study culminates with recommendations concerning the direction for future research.

Sustainable Supply Chain Design: A Configurational Approach

PubMed Central

Masoumik, S. Maryam; Raja Ghazilla, Raja Ariffin

2014-01-01

Designing the right supply chain that meets the requirements of sustainable development is a significant challenge. Although there are a considerable number of studies on issues relating to sustainable supply chain design (SSCD) in terms of designing the practices, processes, and structures, they have rarely demonstrated how these components can be aligned to form an effective sustainable supply chain (SSC). Considering this gap in the literature, this study adopts the configurational approach to develop a conceptual framework that could configure the components of a SSC. In this respect, a process-oriented approach is utilized to classify and harmonize the design components. A natural-resource-based view (NRBV) is adopted to determine the central theme to align the design components around. The proposed framework presents three types of SSC, namely, efficient SSC, innovative SSC, and reputed SSC. The study culminates with recommendations concerning the direction for future research. PMID:24523652

Planning for Materials Processing in Space

NASA Technical Reports Server (NTRS)

1977-01-01

A systems design study to describe the conceptual evolution, the institutional interrelationshiphs, and the basic physical requirements to implement materials processing in space was conducted. Planning for a processing era, rather than hardware design, was emphasized. Product development in space was examined in terms of fluid phenomena, phase separation, and heat and mass transfer. The effect of materials processing on the environment was studied. A concept for modular, unmanned orbiting facilities using the modified external tank of the space shuttle is presented. Organizational and finding structures which would provide for the efficient movement of materials from user to space are discussed.

Sensory processing and world modeling for an active ranging device

NASA Technical Reports Server (NTRS)

Hong, Tsai-Hong; Wu, Angela Y.

1991-01-01

In this project, we studied world modeling and sensory processing for laser range data. World Model data representation and operation were defined. Sensory processing algorithms for point processing and linear feature detection were designed and implemented. The interface between world modeling and sensory processing in the Servo and Primitive levels was investigated and implemented. In the primitive level, linear features detectors for edges were also implemented, analyzed and compared. The existing world model representations is surveyed. Also presented is the design and implementation of the Y-frame model, a hierarchical world model. The interfaces between the world model module and the sensory processing module are discussed as well as the linear feature detectors that were designed and implemented.

Study of a Fine Grained Threaded Framework Design

NASA Astrophysics Data System (ADS)

Jones, C. D.

2012-12-01

Traditionally, HEP experiments exploit the multiple cores in a CPU by having each core process one event. However, future PC designs are expected to use CPUs which double the number of processing cores at the same rate as the cost of memory falls by a factor of two. This effectively means the amount of memory per processing core will remain constant. This is a major challenge for LHC processing frameworks since the LHC is expected to deliver more complex events (e.g. greater pileup events) in the coming years while the LHC experiment's frameworks are already memory constrained. Therefore in the not so distant future we may need to be able to efficiently use multiple cores to process one event. In this presentation we will discuss a design for an HEP processing framework which can allow very fine grained parallelization within one event as well as supporting processing multiple events simultaneously while minimizing the memory footprint of the job. The design is built around the libdispatch framework created by Apple Inc. (a port for Linux is available) whose central concept is the use of task queues. This design also accommodates the reality that not all code will be thread safe and therefore allows one to easily mark modules or sub parts of modules as being thread unsafe. In addition, the design efficiently handles the requirement that events in one run must all be processed before starting to process events from a different run. After explaining the design we will provide measurements from simulating different processing scenarios where the processing times used for the simulation are drawn from processing times measured from actual CMS event processing.

Investigation of Low-Reynolds-Number Rocket Nozzle Design Using PNS-Based Optimization Procedure

NASA Technical Reports Server (NTRS)

Hussaini, M. Moin; Korte, John J.

1996-01-01

An optimization approach to rocket nozzle design, based on computational fluid dynamics (CFD) methodology, is investigated for low-Reynolds-number cases. This study is undertaken to determine the benefits of this approach over those of classical design processes such as Rao's method. A CFD-based optimization procedure, using the parabolized Navier-Stokes (PNS) equations, is used to design conical and contoured axisymmetric nozzles. The advantage of this procedure is that it accounts for viscosity during the design process; other processes make an approximated boundary-layer correction after an inviscid design is created. Results showed significant improvement in the nozzle thrust coefficient over that of the baseline case; however, the unusual nozzle design necessitates further investigation of the accuracy of the PNS equations for modeling expanding flows with thick laminar boundary layers.

Aviation Human-in-the-Loop Simulation Studies: Experimental Planning, Design, and Data Management

DTIC Science & Technology

2014-01-01

Aviation Human-in-the-Loop Simulation Studies: Experimental Planning, Design , and Data Management Kevin W. Williams1 Bonny Christopher2 Gena...Simulation Studies: Experimental Planning, Design , and Data Management January 2014 6. Performing Organization Code 7. Author(s) 8. Performing...describe the process by which we designed our human-in-the-loop (HITL) simulation study and the methodology used to collect and analyze the results

Study on reservoir time-varying design flood of inflow based on Poisson process with time-dependent parameters

NASA Astrophysics Data System (ADS)

Li, Jiqing; Huang, Jing; Li, Jianchang

2018-06-01

The time-varying design flood can make full use of the measured data, which can provide the reservoir with the basis of both flood control and operation scheduling. This paper adopts peak over threshold method for flood sampling in unit periods and Poisson process with time-dependent parameters model for simulation of reservoirs time-varying design flood. Considering the relationship between the model parameters and hypothesis, this paper presents the over-threshold intensity, the fitting degree of Poisson distribution and the design flood parameters are the time-varying design flood unit period and threshold discriminant basis, deduced Longyangxia reservoir time-varying design flood process at 9 kinds of design frequencies. The time-varying design flood of inflow is closer to the reservoir actual inflow conditions, which can be used to adjust the operating water level in flood season and make plans for resource utilization of flood in the basin.

Evaluating the process parameters of the dry coating process using a 2(5-1) factorial design.

PubMed

Kablitz, Caroline Désirée; Urbanetz, Nora Anne

2013-02-01

A recent development of coating technology is dry coating, where polymer powder and liquid plasticizer are layered on the cores without using organic solvents or water. Several studies evaluating the process were introduced in literature, however, little information about the critical process parameters (CPPs) is given. Aim of the study was the investigation and optimization of CPPs with respect to one of the critical quality attributes (CQAs), the coating efficiency of the dry coating process in a rotary fluid bed. Theophylline pellets were coated with hydroxypropyl methylcellulose acetate succinate as enteric film former and triethyl citrate and acetylated monoglyceride as plasticizer. A 2(5-1) design of experiments (DOEs) was created investigating five independent process parameters namely coating temperature, curing temperature, feeding/spraying rate, air flow and rotor speed. The results were evaluated by multilinear regression using the software Modde(®) 7. It is shown, that generally, low feeding/spraying rates and low rotor speeds increase coating efficiency. High coating temperatures enhance coating efficiency, whereas medium curing temperatures have been found to be optimum in terms of coating efficiency. This study provides a scientific base for the design of efficient dry coating processes with respect to coating efficiency.

Implementation of "Quality by Design (QbD)" Approach for the Development of 5-Fluorouracil Loaded Thermosensitive Hydrogel.

PubMed

Dalwadi, Chintan; Patel, Gayatri

2016-01-01

The purpose of this study was to investigate Quality by Design (QbD) principle for the preparation of hydrogel products to prove both practicability and utility of executing QbD concept to hydrogel based controlled release systems. Product and process understanding will help in decreasing the variability of critical material and process parameters, which give quality product output and reduce the risk. This study includes the identification of the Quality Target Product Profiles (QTPPs) and Critical Quality Attributes (CQAs) from literature or preliminary studies. To identify and control the variability in process and material attributes, two tools of QbD was utilized, Quality Risk Management (QRM) and Experimental Design. Further, it helps to identify the effect of these attributes on CQAs. Potential risk factors were identified from fishbone diagram and screened by risk assessment and optimized by 3-level 2- factor experimental design with center points in triplicate, to analyze the precision of the target process. This optimized formulation was further characterized by gelling time, gelling temperature, rheological parameters, in-vitro biodegradation and in-vitro drug release. Design space was created using experimental design tool that gives the control space and working within this controlled space reduces all the failure modes below the risk level. In conclusion, QbD approach with QRM tool provides potent and effectual pyramid to enhance the quality into the hydrogel.

Design Process for Online Websites Created for Teaching Turkish as a Foreign Language in Web Based Environments

ERIC Educational Resources Information Center

Türker, Fatih Mehmet

2016-01-01

In today's world, where online learning environments have increased their efficiency in education and training, the design of the websites prepared for education and training purposes has become an important process. This study is about the teaching process of the online learning environments created to teach Turkish in web based environments, and…

Using a Systematic Conceptual Model for a Process Evaluation of a Middle School Obesity Risk-Reduction Nutrition Curriculum Intervention: "Choice, Control & Change"

ERIC Educational Resources Information Center

Lee, Heewon; Contento, Isobel R.; Koch, Pamela

2013-01-01

Objective: To use and review a conceptual model of process evaluation and to examine the implementation of a nutrition education curriculum, "Choice, Control & Change", designed to promote dietary and physical activity behaviors that reduce obesity risk. Design: A process evaluation study based on a systematic conceptual model. Setting: Five…

Novel Ergonomic Postural Assessment Method (NERPA) Using Product-Process Computer Aided Engineering for Ergonomic Workplace Design

PubMed Central

Sanchez-Lite, Alberto; Garcia, Manuel; Domingo, Rosario; Angel Sebastian, Miguel

2013-01-01

Background Musculoskeletal disorders (MSDs) that result from poor ergonomic design are one of the occupational disorders of greatest concern in the industrial sector. A key advantage in the primary design phase is to focus on a method of assessment that detects and evaluates the potential risks experienced by the operative when faced with these types of physical injuries. The method of assessment will improve the process design identifying potential ergonomic improvements from various design alternatives or activities undertaken as part of the cycle of continuous improvement throughout the differing phases of the product life cycle. Methodology/Principal Findings This paper presents a novel postural assessment method (NERPA) fit for product-process design, which was developed with the help of a digital human model together with a 3D CAD tool, which is widely used in the aeronautic and automotive industries. The power of 3D visualization and the possibility of studying the actual assembly sequence in a virtual environment can allow the functional performance of the parts to be addressed. Such tools can also provide us with an ergonomic workstation design, together with a competitive advantage in the assembly process. Conclusions The method developed was used in the design of six production lines, studying 240 manual assembly operations and improving 21 of them. This study demonstrated the proposed method’s usefulness and found statistically significant differences in the evaluations of the proposed method and the widely used Rapid Upper Limb Assessment (RULA) method. PMID:23977340

Design and optimization of a chromatographic purification process for Streptococcus pneumoniae serotype 23F capsular polysaccharide by a Design of Experiments approach.

PubMed

Ji, Yu; Tian, Yang; Ahnfelt, Mattias; Sui, Lili

2014-06-27

Multivalent pneumococcal vaccines were used worldwide to protect human beings from pneumococcal diseases. In order to eliminate the toxic organic solutions used in the traditional vaccine purification process, an alternative chromatographic process for Streptococcus pneumoniae serotype 23F capsular polysaccharide (CPS) was proposed in this study. The strategy of Design of Experiments (DoE) was introduced into the process development to solve the complicated design procedure. An initial process analysis was given to review the whole flowchart, identify the critical factors of chromatography through FMEA and chose the flowthrough mode due to the property of the feed. A resin screening study was then followed to select candidate resins. DoE was utilized to generate a resolution IV fractional factorial design to further compare candidates and narrow down the design space. After Capto Adhere was selected, the Box-Behnken DoE was executed to model the process and characterize all effects of factors on the responses. Finally, Monte Carlo simulation was used to optimize the process, test the chosen optimal conditions and define the control limit. The results of three scale-up runs at set points verified the DoE and simulation predictions. The final results were well in accordance with the EU pharmacopeia requirements: Protein/CPS (w/w) 1.08%; DNA/CPS (w/w) 0.61%; the phosphorus content 3.1%; the nitrogen 0.315% and the Methyl-pentose percentage 47.9%. Other tests of final pure CPS also met the pharmacopeia specifications. This alternative chromatographic purification process for pneumococcal vaccine without toxic organic solvents was successfully developed by the DoE approach and proved scalability, robustness and suitability for large scale manufacturing. Copyright © 2014 Elsevier B.V. All rights reserved.

The Role of Re-Appropriation in Open Design: A Case Study on How Openness in Higher Education for Industrial Design Engineering Can Trigger Global Discussions on the Theme of Urban Gardening

ERIC Educational Resources Information Center

Ostuzzi, Francesca; Conradie, Peter; De Couvreur, Lieven; Detand, Jan; Saldien, Jelle

2016-01-01

This case study explores the opportunities for students of Industrial Design Engineering to engage with direct and indirect stakeholders by making their design process and results into open-ended designed solutions. The reported case study involved 47 students during a two-weeks intensive course on the topic of urban gardening. Observations were…

Effectiveness of Facebook Based Learning to Enhance Creativity among Islamic Studies Students by Employing Isman Instructional Design Model

ERIC Educational Resources Information Center

Alias, Norlidah; Siraj, Saedah; Daud, Mohd Khairul Azman Md; Hussin, Zaharah

2013-01-01

The study examines the effectiveness of Facebook based learning to enhance creativity among Islamic Studies students in the secondary educational setting in Malaysia. It describes the design process by employing the Isman Instructional Design Model. A quantitative study was carried out using experimental method and background survey. The…

DHM simulation in virtual environments: a case-study on control room design.

PubMed

Zamberlan, M; Santos, V; Streit, P; Oliveira, J; Cury, R; Negri, T; Pastura, F; Guimarães, C; Cid, G

2012-01-01

This paper will present the workflow developed for the application of serious games in the design of complex cooperative work settings. The project was based on ergonomic studies and development of a control room among participative design process. Our main concerns were the 3D human virtual representation acquired from 3D scanning, human interaction, workspace layout and equipment designed considering ergonomics standards. Using Unity3D platform to design the virtual environment, the virtual human model can be controlled by users on dynamic scenario in order to evaluate the new work settings and simulate work activities. The results obtained showed that this virtual technology can drastically change the design process by improving the level of interaction between final users and, managers and human factors team.

Designing Teaching--Teaching Designing: Teacher's Guidance in a Virtual Design Studio

ERIC Educational Resources Information Center

Lahti, Henna; Seitamaa-Hakkarainen, Pirita

2014-01-01

This study examined pedagogical aspects of virtual designing. It focused on how an industrial design teacher organised a university course in plastic product design and how the teacher guided student teams' design processes in a virtual design studio. The model of Learning by Collaborative Design was used as a pedagogical and analytical framework.…

Basic Design, a Needed Foundation for Designing a Successful Garment: A Case Study of Dressmakers in the Ho Municipality, Volta Region, Ghana

ERIC Educational Resources Information Center

Gbetodeme, Selom; Amankwa, Joana; Dzegblor, Noble Komla

2016-01-01

To facilitate the design process in every art form, there are certain guidelines that all professional designers should use. These are known as elements and principles of design. This study is a survey carried out to assess the knowledge of dressmakers about basic design in the Ho Municipality of Ghana. Sixty dressmakers were randomly sampled for…

What Does Design and Technology Learning Really Look Like?

ERIC Educational Resources Information Center

Southall, Mary

2016-01-01

This paper presents findings from a research study investigating the relationship between "intended" learning and "actual" learning in Design and Technology lessons (Southall, 2015). The research focused upon the "pre active" phase of the teaching-learning process, that is the teacher's planning processes and…

Assessment of pictographs developed through a participatory design process using an online survey tool.

PubMed

Kim, Hyeoneui; Nakamura, Carlos; Zeng-Treitler, Qing

2009-02-24

Inpatient discharge instructions are a mandatory requirement of the Centers for Medicare and Medicaid Services and Joint Commission on Accreditation of Healthcare Organizations. The instructions include all the information relevant to post-discharge patient care. Prior studies show that patients often cannot fully understand or remember all the instructions. To address this issue, we have previously conducted a pilot study in which pictographs were created through a participatory design process to facilitate the comprehension and recall of discharge instructions. The main objective of this study was to verify the individual effectiveness of pictographs created through a participatory design process. In this study, we included 20 pictographs developed by our group and 20 pictographs developed by the Robert Wood Johnson Foundation as a reference baseline for pictographic recognition. To assess whether the participants could recognize the meaning of the pictographs, we designed an asymmetrical pictograph-text label-linking test. Data collection lasted for 7 days after the email invitation. A total of 44 people accessed the survey site. We excluded 7 participants who completed less than 50% of the survey. A total of 719 answers from 37 participants were analyzed. The analysis showed that the participants recognized the pictographs developed in-house significantly better than those included in the study as a baseline (P< .001). This trend was true regardless of the participant's gender, age, and education level. The results also revealed that there is a large variance in the quality of the pictographs developed using the same design process-the recognition rate ranged from below 50% to above 90%. This study confirmed that the majority of the pictographs developed in a participatory design process involving a small number of nurses and consumers were recognizable by a larger number of consumers. The variance in recognition rates suggests that pictographs should be assessed individually before being evaluated within the context of an application.

To Explore the Effect of Sub Consciousness on Sudden Moments of Inspiration (SMI) in the Sketching Process of Industrial Design

ERIC Educational Resources Information Center

Wu, Qun; Wang, Yecheng

2015-01-01

The purpose of this study is to identify the occurrence of Sudden Moments of Inspiration (SMI) in the sketching process of industrial design through experiments to explain the effect of sub consciousness on SMI. There are a pre-experiment and a formal experiment. In the formal experiment, nine undergraduates majoring in industrial design with same…

Superstructure-based Design and Optimization of Batch Biodiesel Production Using Heterogeneous Catalysts

NASA Astrophysics Data System (ADS)

Nuh, M. Z.; Nasir, N. F.

2017-08-01

Biodiesel as a fuel comprised of mono alkyl esters of long chain fatty acids derived from renewable lipid feedstock, such as vegetable oil and animal fat. Biodiesel production is complex process which need systematic design and optimization. However, no case study using the process system engineering (PSE) elements which are superstructure optimization of batch process, it involves complex problems and uses mixed-integer nonlinear programming (MINLP). The PSE offers a solution to complex engineering system by enabling the use of viable tools and techniques to better manage and comprehend the complexity of the system. This study is aimed to apply the PSE tools for the simulation of biodiesel process and optimization and to develop mathematical models for component of the plant for case A, B, C by using published kinetic data. Secondly, to determine economic analysis for biodiesel production, focusing on heterogeneous catalyst. Finally, the objective of this study is to develop the superstructure for biodiesel production by using heterogeneous catalyst. The mathematical models are developed by the superstructure and solving the resulting mixed integer non-linear model and estimation economic analysis by using MATLAB software. The results of the optimization process with the objective function of minimizing the annual production cost by batch process from case C is 23.2587 million USD. Overall, the implementation a study of process system engineering (PSE) has optimized the process of modelling, design and cost estimation. By optimizing the process, it results in solving the complex production and processing of biodiesel by batch.

Nurses and nurse assistants' experiences with using a design thinking approach to innovation in a nursing home.

PubMed

Eines, Trude Fløystad; Vatne, Solfrid

2018-05-01

The aim of this study was to evaluate nurses' and nurse assistants' experiences with a design thinking approach to innovation used in a nursing home in Norway. A design thinking approach to innovation that focuses on users' needs can be employed to address many of the challenges facing health care providers in a field facing a growing ageing population, complex diseases and financial shortfalls. This study is based on a thematic analysis of four focus group interviews with nurses and nurse assistants (n = 23). In the initial phase of developing the new service model, which included defining staff roles and responsibilities, participating nurses and nurse assistants felt engaged and motivated by the designers' inclusive and creative methods. However, during the new model's testing phase, they were critical of management's lack of involvement in the model`s implementation and therefore became less motivated about the project. The findings of the study highlight the importance of the designers cooperating with management and staff for the duration of the innovation process. Challenging innovation processes require strong managers who engage with designers, patients, staff and volunteers throughout all phases of an innovation process using a design thinking approach. © 2017 John Wiley & Sons Ltd.

Collaboration within Student Design Teams Participating in Architectural Design Competitions

ERIC Educational Resources Information Center

Erbil, Livanur; Dogan, Fehmi

2012-01-01

This paper investigates design collaboration with reference to convergent and divergent idea generation processes in architectural design teams entering a design competition. Study of design teams offer a unique opportunity to investigate how creativity is fostered through collaborative work. While views of creativity often relate creativity to…

Nanohole Arrays of Mixed Designs and Microwriting for Simultaneous and Multiple Protein Binding Studies

PubMed Central

Ji, Jin; Yang, Jiun-Chan; Larson, Dale N.

2009-01-01

We demonstrate using nanohole arrays of mixed designs and a microwriting process based on dip-pen nanolithography to monitor multiple, different protein binding events simultaneously in real time based on the intensity of Extraordinary Optical Transmission of nanohole arrays. The microwriting process and small footprint of the individual nanohole arrays enabled us to observe different binding events located only 16μm apart, achieving high spatial resolution. We also present a novel concept that incorporates nanohole arrays of different designs to improve confidence and accuracy of binding studies. For proof of concept, two types of nanohole arrays, designed to exhibit opposite responses to protein bindings, were fabricated on one transducer. Initial studies indicate that the mixed designs could help to screen out artifacts such as protein intrinsic signals, providing improved accuracy of binding interpretation. PMID:19297143

A Taguchi study of the aeroelastic tailoring design process

NASA Technical Reports Server (NTRS)

Bohlmann, Jonathan D.; Scott, Robert C.

1991-01-01

A Taguchi study was performed to determine the important players in the aeroelastic tailoring design process and to find the best composition of the optimization's objective function. The Wing Aeroelastic Synthesis Procedure (TSO) was used to ascertain the effects that factors such as composite laminate constraints, roll effectiveness constraints, and built-in wing twist and camber have on the optimum, aeroelastically tailored wing skin design. The results show the Taguchi method to be a viable engineering tool for computational inquiries, and provide some valuable lessons about the practice of aeroelastic tailoring.

DIY 3D printing of custom orthopaedic implants: a proof of concept study.

PubMed

Frame, Mark; Leach, William

2014-03-01

3D printing is an emerging technology that is primarily used for aiding the design and prototyping of implants. As this technology has evolved it has now become possible to produce functional and definitive implants manufactured using a 3D printing process. This process, however, previously required a large financial investment in complex machinery and professionals skilled in 3D product design. Our pilot study's aim was to design and create a 3D printed custom orthopaedic implant using only freely available consumer hardware and software.

Multiqubit Clifford groups are unitary 3-designs

NASA Astrophysics Data System (ADS)

Zhu, Huangjun

2017-12-01

Unitary t -designs are a ubiquitous tool in many research areas, including randomized benchmarking, quantum process tomography, and scrambling. Despite the intensive efforts of many researchers, little is known about unitary t -designs with t ≥3 in the literature. We show that the multiqubit Clifford group in any even prime-power dimension is not only a unitary 2-design, but also a 3-design. Moreover, it is a minimal 3-design except for dimension 4. As an immediate consequence, any orbit of pure states of the multiqubit Clifford group forms a complex projective 3-design; in particular, the set of stabilizer states forms a 3-design. In addition, our study is helpful in studying higher moments of the Clifford group, which are useful in many research areas ranging from quantum information science to signal processing. Furthermore, we reveal a surprising connection between unitary 3-designs and the physics of discrete phase spaces and thereby offer a simple explanation of why no discrete Wigner function is covariant with respect to the multiqubit Clifford group, which is of intrinsic interest in studying quantum computation.

Design, scale-up, Six Sigma in processing different feedstocks in a fixed bed downdraft biomass gasifier

NASA Astrophysics Data System (ADS)

Boravelli, Sai Chandra Teja

This thesis mainly focuses on design and process development of a downdraft biomass gasification processes. The objective is to develop a gasifier and process of gasification for a continuous steady state process. A lab scale downdraft gasifier was designed to develop the process and obtain optimum operating procedure. Sustainable and dependable sources such as biomass are potential sources of renewable energy and have a reasonable motivation to be used in developing a small scale energy production plant for countries such as Canada where wood stocks are more reliable sources than fossil fuels. This thesis addresses the process of thermal conversion of biomass gasification process in a downdraft reactor. Downdraft biomass gasifiers are relatively cheap and easy to operate because of their design. We constructed a simple biomass gasifier to study the steady state process for different sizes of the reactor. The experimental part of this investigation look at how operating conditions such as feed rate, air flow, the length of the bed, the vibration of the reactor, height and density of syngas flame in combustion flare changes for different sizes of the reactor. These experimental results also compare the trends of tar, char and syngas production for wood pellets in a steady state process. This study also includes biomass gasification process for different wood feedstocks. It compares how shape, size and moisture content of different feedstocks makes a difference in operating conditions for the gasification process. For this, Six Sigma DMAIC techniques were used to analyze and understand how each feedstock makes a significant impact on the process.

Comprehensive assessment of the L-lysine production process from fermentation of sugarcane molasses.

PubMed

Anaya-Reza, Omar; Lopez-Arenas, Teresa

2017-07-01

L-Lysine is an essential amino acid that can be produced by chemical processes from fossil raw materials, as well as by microbial fermentation, the latter being a more efficient and environmentally friendly procedure. In this work, the production process of L-lysine-HCl is studied using a systematic approach based on modeling and simulation, which supports decision making in the early stage of process design. The study considers two analysis stages: first, the dynamic analysis of the fermentation reactor, where the conversion of sugars from sugarcane molasses to L-lysine with a strain of Corynebacterium glutamicum is carried out. In this stage, the operation mode (either batch or fed batch) and operating conditions of the fermentation reactor are defined to reach the maximum technical criteria. Afterwards, the second analysis stage relates to the industrial production process of L-lysine-HCl, where the fermentation reactor, upstream processing, and downstream processing are included. In this stage, the influence of key parameters on the overall process performance is scrutinized through the evaluation of several technical, economic, and environmental criteria, to determine a profitable and sustainable design of the L-lysine production process. The main results show how the operating conditions, process design, and selection of evaluation criteria can influence in the conceptual design. The best plant design shows maximum product yield (0.31 g L-lysine/g glucose) and productivity (1.99 g/L/h), achieving 26.5% return on investment (ROI) with a payback period (PBP) of 3.8 years, decreasing water and energy consumption, and with a low potential environmental impact (PEI) index.

The Investigation of Science Process Skills of Science Teachers in Terms of Some Variables

ERIC Educational Resources Information Center

Aydogdu, Bülent

2015-01-01

This study aimed to investigate basic process skills, integrated process skills and overall science process skills of science teachers in terms of some variables. This study had a survey design. The study population consisted of 170 science teachers from a province located in the Central Anatolia Region of Turkey. The study data were obtained from…

Space station automation study: Automation requirements derived from space manufacturing concepts. Volume 1: Executive summary

NASA Technical Reports Server (NTRS)

1984-01-01

The electroepitaxial process and the Very Large Scale Integration (VLSI) circuits (chips) facilities were chosen because each requires a very high degree of automation, and therefore involved extensive use of teleoperators, robotics, process mechanization, and artificial intelligence. Both cover a raw materials process and a sophisticated multi-step process and are therfore highly representative of the kinds of difficult operation, maintenance, and repair challenges which can be expected for any type of space manufacturing facility. Generic areas were identified which will require significant further study. The initial design will be based on terrestrial state-of-the-art hard automation. One hundred candidate missions were evaluated on the basis of automation portential and availability of meaning ful knowldege. The design requirements and unconstrained design concepts developed for the two missions are presented.

Study of mould design and forming process on advanced polymer-matrix composite complex structure

NASA Astrophysics Data System (ADS)

Li, S. J.; Zhan, L. H.; Bai, H. M.; Chen, X. P.; Zhou, Y. Q.

2015-07-01

Advanced carbon fibre-reinforced polymer-matrix composites are widely applied to aviation manufacturing field due to their outstanding performance. In this paper, the mould design and forming process of the complex composite structure were discussed in detail using the hat stiffened structure as an example. The key issues of the moulddesign were analyzed, and the corresponding solutions were also presented. The crucial control points of the forming process such as the determination of materials and stacking sequence, the temperature and pressure route of the co-curing process were introduced. In order to guarantee the forming quality of the composite hat stiffened structure, a mathematical model about the aperture of rubber mandrel was introduced. The study presented in this paper may provide some actual references for the design and manufacture of the important complex composite structures.

Design optimization for active twist rotor blades

NASA Astrophysics Data System (ADS)

Mok, Ji Won

This dissertation introduces the process of optimizing active twist rotor blades in the presence of embedded anisotropic piezo-composite actuators. Optimum design of active twist blades is a complex task, since it involves a rich design space with tightly coupled design variables. The study presents the development of an optimization framework for active helicopter rotor blade cross-sectional design. This optimization framework allows for exploring a rich and highly nonlinear design space in order to optimize the active twist rotor blades. Different analytical components are combined in the framework: cross-sectional analysis (UM/VABS), an automated mesh generator, a beam solver (DYMORE), a three-dimensional local strain recovery module, and a gradient based optimizer within MATLAB. Through the mathematical optimization problem, the static twist actuation performance of a blade is maximized while satisfying a series of blade constraints. These constraints are associated with locations of the center of gravity and elastic axis, blade mass per unit span, fundamental rotating blade frequencies, and the blade strength based on local three-dimensional strain fields under worst loading conditions. Through pre-processing, limitations of the proposed process have been studied. When limitations were detected, resolution strategies were proposed. These include mesh overlapping, element distortion, trailing edge tab modeling, electrode modeling and foam implementation of the mesh generator, and the initial point sensibility of the current optimization scheme. Examples demonstrate the effectiveness of this process. Optimization studies were performed on the NASA/Army/MIT ATR blade case. Even though that design was built and shown significant impact in vibration reduction, the proposed optimization process showed that the design could be improved significantly. The second example, based on a model scale of the AH-64D Apache blade, emphasized the capability of this framework to explore the nonlinear design space of complex planform. Especially for this case, detailed design is carried out to make the actual blade manufacturable. The proposed optimization framework is shown to be an effective tool to design high authority active twist blades to reduce vibration in future helicopter rotor blades.

From the past to the future: Integrating work experience into the design process.

PubMed

Bittencourt, João Marcos; Duarte, Francisco; Béguin, Pascal

2017-01-01

Integrating work activity issues into design process is a broadly discussed theme in ergonomics. Participation is presented as the main means for such integration. However, a late participation can limit the development of both project solutions and future work activity. This article presents the concept of construction of experience aiming at the articulated development of future activities and project solutions. It is a non-teleological approach where the initial concepts will be transformed by the experience built up throughout the design process. The method applied was a case study of an ergonomic participation during the design of a new laboratory complex for biotechnology research. Data was obtained through analysis of records in a simulation process using a Lego scale model and interviews with project participants. The simulation process allowed for developing new ways of working and generating changes in the initial design solutions, which enable workers to adopt their own developed strategies for conducting work more safely and efficiently in the future work system. Each project decision either opens or closes a window of opportunities for developing a future activity. Construction of experience in a non-teleological design process allows for understanding the consequences of project solutions for future work.

Parametric and Generative Design Techniques for Digitalization in Building Industry: the Case Study of Glued- Laminated-Timber Industry

NASA Astrophysics Data System (ADS)

Pasetti Monizza, G.; Matt, D. T.; Benedetti, C.

2016-11-01

According to Wortmann classification, the Building Industry (BI) can be defined as engineer-to-order (ETO) industry: the engineering-process starts only when an order is acquired. This definition implies that every final product (building) is almost unique’ and processes cannot be easily standardized or automated. Because of this, BI is one of the less efficient industries today’ mostly leaded by craftsmanship. In the last years’ several improvements in process efficiency have been made focusing on manufacturing and installation processes only. In order to improve the efficiency of design and engineering processes as well, the scientific community agrees that the most fruitful strategy should be Front-End Design (FED). Nevertheless, effective techniques and tools are missing. This paper discusses outcomes of a research activity that aims at highlighting whether Parametric and Generative Design techniques allow reducing wastes of resources and improving the overall efficiency of the BI, by pushing the Digitalization of design and engineering processes of products. Focusing on the Glued-Laminated-Timber industry, authors will show how Parametric and Generative Design techniques can be introduced in a standard supply-chain system, highlighting potentials and criticism on the supply-chain system as a whole.

Designing for Quality: An Analysis of Design and Pedagogical Issues in Online Course Development

ERIC Educational Resources Information Center

Sanga, Mapopa William

2017-01-01

This study investigated the process through which 100 online courses were developed in compliance with a purpose-made rubric designed to bring the courses to a level that would meet requirements of membership in a state authorization reciprocity agreement. The study identified and analyzed common design and pedagogical issues instructors…

Teachers as Participatory Designers: Two Case Studies with Technology-Enhanced Learning Environments

ERIC Educational Resources Information Center

Cober, Rebecca; Tan, Esther; Slotta, Jim; So, Hyo-Jeong; Könings, Karen D.

2015-01-01

Teachers are not typically involved as participatory designers in the design of technology-enhanced learning environments. As they have unique and valuable perspectives on the role of technology in education, it is of utmost importance to engage them in a participatory design process. Adopting a case study methodology, we aim to reveal in what…

High School Students' Use of Paper-Based and Internet-Based Information Sources in the Engineering Design Process

ERIC Educational Resources Information Center

Pieper, Jon; Mentzer, Nathan

2013-01-01

Mentzer and Becker (2011) and Becker and Mentzer (2012) demonstrated that high school students engaged in engineering design problems spent more time accessing information and spent more time designing when provided with Internet access. They studied high school students engaged in an engineering design challenge. The two studies attempted to…

Design of experiments utilization to map the processing capabilities of a micro-spray dryer: particle design and throughput optimization in support of drug discovery.

PubMed

Ormes, James D; Zhang, Dan; Chen, Alex M; Hou, Shirley; Krueger, Davida; Nelson, Todd; Templeton, Allen

2013-02-01

There has been a growing interest in amorphous solid dispersions for bioavailability enhancement in drug discovery. Spray drying, as shown in this study, is well suited to produce prototype amorphous dispersions in the Candidate Selection stage where drug supply is limited. This investigation mapped the processing window of a micro-spray dryer to achieve desired particle characteristics and optimize throughput/yield. Effects of processing variables on the properties of hypromellose acetate succinate were evaluated by a fractional factorial design of experiments. Parameters studied include solid loading, atomization, nozzle size, and spray rate. Response variables include particle size, morphology and yield. Unlike most other commercial small-scale spray dryers, the ProCepT was capable of producing particles with a relatively wide mean particle size, ca. 2-35 µm, allowing material properties to be tailored to support various applications. In addition, an optimized throughput of 35 g/hour with a yield of 75-95% was achieved, which affords to support studies from Lead-identification/Lead-optimization to early safety studies. A regression model was constructed to quantify the relationship between processing parameters and the response variables. The response surface curves provide a useful tool to design processing conditions, leading to a reduction in development time and drug usage to support drug discovery.

Optimization of MLS receivers for multipath environments

NASA Technical Reports Server (NTRS)

Mcalpine, G. A.; Highfill, J. H., III

1976-01-01

The design of a microwave landing system (MLS) aircraft receiver, capable of optimal performance in multipath environments found in air terminal areas, is reported. Special attention was given to the angle tracking problem of the receiver and includes tracking system design considerations, study and application of locally optimum estimation involving multipath adaptive reception and then envelope processing, and microcomputer system design. Results show processing is competitive in this application with i-f signal processing performance-wise and is much more simple and cheaper. A summary of the signal model is given.

Application of a quality by design approach to the cell culture process of monoclonal antibody production, resulting in the establishment of a design space.

PubMed

Nagashima, Hiroaki; Watari, Akiko; Shinoda, Yasuharu; Okamoto, Hiroshi; Takuma, Shinya

2013-12-01

This case study describes the application of Quality by Design elements to the process of culturing Chinese hamster ovary cells in the production of a monoclonal antibody. All steps in the cell culture process and all process parameters in each step were identified by using a cause-and-effect diagram. Prospective risk assessment using failure mode and effects analysis identified the following four potential critical process parameters in the production culture step: initial viable cell density, culture duration, pH, and temperature. These parameters and lot-to-lot variability in raw material were then evaluated by process characterization utilizing a design of experiments approach consisting of a face-centered central composite design integrated with a full factorial design. Process characterization was conducted using a scaled down model that had been qualified by comparison with large-scale production data. Multivariate regression analysis was used to establish statistical prediction models for performance indicators and quality attributes; with these, we constructed contour plots and conducted Monte Carlo simulation to clarify the design space. The statistical analyses, especially for raw materials, identified set point values, which were most robust with respect to the lot-to-lot variability of raw materials while keeping the product quality within the acceptance criteria. © 2013 Wiley Periodicals, Inc. and the American Pharmacists Association.

Using Systems Theory to Examine Patient and Nurse Structures, Processes, and Outcomes in Centralized and Decentralized Units.

PubMed

Real, Kevin; Fay, Lindsey; Isaacs, Kathy; Carll-White, Allison; Schadler, Aric

2018-01-01

This study utilizes systems theory to understand how changes to physical design structures impact communication processes and patient and staff design-related outcomes. Many scholars and researchers have noted the importance of communication and teamwork for patient care quality. Few studies have examined changes to nursing station design within a systems theory framework. This study employed a multimethod, before-and-after, quasi-experimental research design. Nurses completed surveys in centralized units and later in decentralized units ( N = 26 pre , N = 51 post ). Patients completed surveys ( N = 62 pre ) in centralized units and later in decentralized units ( N = 49 post ). Surveys included quantitative measures and qualitative open-ended responses. Patients preferred the decentralized units because of larger single-occupancy rooms, greater privacy/confidentiality, and overall satisfaction with design. Nurses had a more complex response. Nurses approved the patient rooms, unit environment, and noise levels in decentralized units. However, they reported reduced access to support spaces, lower levels of team/mentoring communication, and less satisfaction with design than in centralized units. Qualitative findings supported these results. Nurses were more positive about centralized units and patients were more positive toward decentralized units. The results of this study suggest a need to understand how system components operate in concert. A major contribution of this study is the inclusion of patient satisfaction with design, an important yet overlooked fact in patient satisfaction. Healthcare design researchers and practitioners may consider how changing system interdependencies can lead to unexpected changes to communication processes and system outcomes in complex systems.

Reducing Physical Risk Factors in Construction Work Through a Participatory Intervention: Protocol for a Mixed-Methods Process Evaluation.

PubMed

Ajslev, Jeppe; Brandt, Mikkel; Møller, Jeppe Lykke; Skals, Sebastian; Vinstrup, Jonas; Jakobsen, Markus Due; Sundstrup, Emil; Madeleine, Pascal; Andersen, Lars Louis

2016-05-26

Previous research has shown that reducing physical workload among workers in the construction industry is complicated. In order to address this issue, we developed a process evaluation in a formative mixed-methods design, drawing on existing knowledge of the potential barriers for implementation. We present the design of a mixed-methods process evaluation of the organizational, social, and subjective practices that play roles in the intervention study, integrating technical measurements to detect excessive physical exertion measured with electromyography and accelerometers, video documentation of working tasks, and a 3-phased workshop program. The evaluation is designed in an adapted process evaluation framework, addressing recruitment, reach, fidelity, satisfaction, intervention delivery, intervention received, and context of the intervention companies. Observational studies, interviews, and questionnaires among 80 construction workers organized in 20 work gangs, as well as health and safety staff, contribute to the creation of knowledge about these phenomena. At the time of publication, the process of participant recruitment is underway. Intervention studies are challenging to conduct and evaluate in the construction industry, often because of narrow time frames and ever-changing contexts. The mixed-methods design presents opportunities for obtaining detailed knowledge of the practices intra-acting with the intervention, while offering the opportunity to customize parts of the intervention.

From pattern to process: The strategy of the Earth Observing System: Volume 2: EOS Science Steering Committee report

NASA Technical Reports Server (NTRS)

1987-01-01

The Earth Observing System (EOS) represents a new approach to the study of the Earth. It consists of remotely sensed and correlative in situ observations designed to address important, interrelated global-scale processes. There is an urgent need to study the Earth as a complete, integrated system in order to understand and predict changes caused by human activities and natural processes. The EOS approach is based on an information system concept and designed to provide a long-term study of the Earth using a variety of measurement methods from both operational and research satellite payloads and continuing ground-based Earth science studies. The EOS concept builds on the foundation of the earlier, single-discipline space missions designed for relatively short observation periods. Continued progress in our understanding of the Earth as a system will come from EOS observations spanning several decades using a variety of contemporaneous measurements.

The UARS and open data system concept and analysis study. Executive summary

NASA Technical Reports Server (NTRS)

Mittal, M.; Nebb, J.; Woodward, H.

1983-01-01

Alternative concepts for a common design for the UARS and OPEN Central Data Handling Facility (CDHF) are offered. The designs are consistent with requirements shared by UARS and OPEN and the data storage and data processing demands of these missions. Because more detailed information is available for UARS, the design approach was to size the system and to select components for a UARS CDHF, but in a manner that does not optimize the CDHF at the expense of OPEN. Costs for alternative implementations of the UARS designs are presented showing that the system design does not restrict the implementation to a single manufacturer. Processing demands on the alternative UARS CDHF implementations are discussed. With this information at hand together with estimates for OPEN processing demands, it is shown that any shortfall in system capability for OPEN support can be remedied by either component upgrades or array processing attachments rather than a system redesign.

System importance measures: A new approach to resilient systems-of-systems

NASA Astrophysics Data System (ADS)

Uday, Payuna

Resilience is the ability to withstand and recover rapidly from disruptions. While this attribute has been the focus of research in several fields, in the case of system-of-systems (SoSs), addressing resilience is particularly interesting and challenging. As infrastructure SoSs, such as power, transportation, and communication networks, grow in complexity and interconnectivity, measuring and improving the resilience of these SoSs is vital in terms of safety and providing uninterrupted services. The characteristics of systems-of-systems make analysis and design of resilience challenging. However, these features also offer opportunities to make SoSs resilient using unconventional methods. In this research, we present a new approach to the process of resilience design. The core idea behind the proposed design process is a set of system importance measures (SIMs) that identify systems crucial to overall resilience. Using the results from the SIMs, we determine appropriate strategies from a list of design principles to improve SoS resilience. The main contribution of this research is the development of an aid to design that provides specific guidance on where and how resources need to be targeted. Based on the needs of an SoS, decision-makers can iterate through the design process to identify a set of practical and effective design improvements. We use two case studies to demonstrate how the SIM-based design process can inform decision-making in the context of SoS resilience. The first case study focuses on a naval warfare SoS and describes how the resilience framework can leverage existing simulation models to support end-to-end design. We proceed through stages of the design approach using an agent-based model (ABM) that enables us to demonstrate how simulation tools and analytical models help determine the necessary inputs for the design process and, subsequently, inform decision-making regarding SoS resilience. The second case study considers the urban transportation network in Boston. This case study focuses on interpreting the results of the resilience framework and on describing how they can be used to guide design choices in large infrastructure networks. We use different resilience maps to highlight the range of design-related information that can be obtained from the framework. Specific advantages of the SIM-based resilience design include: (1) incorporates SoS- specific features within existing risk-based design processes - the SIMs determine the relative importance of different systems based on their impacts on SoS-level performance, and suggestions for resilience improvement draw from design options that leverage SoS- specific characteristics, such as the ability to adapt quickly (such as add new systems or re-task existing ones) and to provide partial recovery of performance in the aftermath of a disruption; (2) allows rapid understanding of different areas of concern within the SoS - the visual nature of the resilience map (a key outcome of the SIM analysis) provides a useful way to summarize the current resilience of the SoS as well as point to key systems of concern; and (3) provides a platform for multiple analysts and decision- makers to study, modify, discuss and document options for SoS.

Activating schoolyards: study design of a quasi-experimental schoolyard intervention study.

PubMed

Andersen, Henriette Bondo; Pawlowski, Charlotte Skau; Scheller, Hanne Bebendorf; Troelsen, Jens; Toftager, Mette; Schipperijn, Jasper

2015-05-31

The aim of the Activating Schoolyards Study is to develop, implement, document and assess a comprehensive schoolyard intervention to promote physical activity (PA) during school recess for primary school children (grade 4-8). The intervention is designed to implement organizational and structural changes in the physical environment. The study builds on a quasi-experimental study design using a mixed method approach including: 1) an exploratory study aimed at providing input for the developing process; 2) an evaluation of the effect of the interventions using a combination of accelerometer, GPS and GIS; 3) a process evaluation facilitating the intervention development process and identifying barriers and facilitators in the implementation process; 4) a post-intervention end-user evaluation aimed at exploring who uses the schoolyards and how the schoolyards are used. The seven project schools (cases) were selected by means of an open competition and the interventions were developed using a participatory bottom-up approach. The participatory approach and case selection strategy make the study design novel. The use of a mixed methods design including qualitative as well as quantitative methods can be seen as a strength, as the different types of data complement each other and results of one part of the study informed the following parts. A unique aspect of our study is the use of accelerometers in combination with GPS and GIS in the effect evaluation to objectively determine where and how active the students are in the schoolyard, before and after the intervention. This provides a type of data that, to our knowledge, has not been used before in schoolyard interventions. Exploring the change in behavior in relation to specific intervention elements in the schoolyard will lead to recommendations for schools undergoing schoolyard renovations at some point in the future.

Quantification of construction waste prevented by BIM-based design validation: Case studies in South Korea.

PubMed

Won, Jongsung; Cheng, Jack C P; Lee, Ghang

2016-03-01

Waste generated in construction and demolition processes comprised around 50% of the solid waste in South Korea in 2013. Many cases show that design validation based on building information modeling (BIM) is an effective means to reduce the amount of construction waste since construction waste is mainly generated due to improper design and unexpected changes in the design and construction phases. However, the amount of construction waste that could be avoided by adopting BIM-based design validation has been unknown. This paper aims to estimate the amount of construction waste prevented by a BIM-based design validation process based on the amount of construction waste that might be generated due to design errors. Two project cases in South Korea were studied in this paper, with 381 and 136 design errors detected, respectively during the BIM-based design validation. Each design error was categorized according to its cause and the likelihood of detection before construction. The case studies show that BIM-based design validation could prevent 4.3-15.2% of construction waste that might have been generated without using BIM. Copyright © 2015 Elsevier Ltd. All rights reserved.

Reduction of Aspergillus spp. and aflatoxins in peanut sauce processing by oil-less frying of chilli powder and retort processing.

PubMed

Farawahida, A H; Jinap, S; Nor-Khaizura, M A R; Samsudin, N I P

2017-12-01

Among the many roles played by small and medium enterprises (SMEs) in the food industry is the production of heritage foods such as peanut sauce. Unfortunately, the safety of peanut sauce is not always assured as the processing line is not controlled. Peanut sauce is usually made of peanuts and chilli, and these commodities are normally contaminated with Aspergillus spp. and aflatoxins (AFs). Hence, the objective of this study was to evaluate the practices related to reduction of AF hazard and the effect of interventions in peanut sauce processing. Peanut samples were collected from each step of peanut sauce processing from a small peanut sauce company according to four designs: (1) control; (2) oil-less frying of chilli powder; (3) addition of retort processing; and (4) combination of oil-less frying of chilli powder and retort processing. Oil-less frying of chilli powder (Design 2) reduced total AFs by 33-41%, retort processing (Design 3) reduced total AFs by 49%, while combination of these two thermal processes (Design 4) significantly reduced total AFs, by 57%. The present work demonstrated that Design 4 yielded the highest reduction of total AFs and is therefore recommended to be employed by SME companies.

Optimization of process parameters for a quasi-continuous tablet coating system using design of experiments.

PubMed

Cahyadi, Christine; Heng, Paul Wan Sia; Chan, Lai Wah

2011-03-01

The aim of this study was to identify and optimize the critical process parameters of the newly developed Supercell quasi-continuous coater for optimal tablet coat quality. Design of experiments, aided by multivariate analysis techniques, was used to quantify the effects of various coating process conditions and their interactions on the quality of film-coated tablets. The process parameters varied included batch size, inlet temperature, atomizing pressure, plenum pressure, spray rate and coating level. An initial screening stage was carried out using a 2(6-1(IV)) fractional factorial design. Following these preliminary experiments, optimization study was carried out using the Box-Behnken design. Main response variables measured included drug-loading efficiency, coat thickness variation, and the extent of tablet damage. Apparent optimum conditions were determined by using response surface plots. The process parameters exerted various effects on the different response variables. Hence, trade-offs between individual optima were necessary to obtain the best compromised set of conditions. The adequacy of the optimized process conditions in meeting the combined goals for all responses was indicated by the composite desirability value. By using response surface methodology and optimization, coating conditions which produced coated tablets of high drug-loading efficiency, low incidences of tablet damage and low coat thickness variation were defined. Optimal conditions were found to vary over a large spectrum when different responses were considered. Changes in processing parameters across the design space did not result in drastic changes to coat quality, thereby demonstrating robustness in the Supercell coating process. © 2010 American Association of Pharmaceutical Scientists

Integrating reliability and maintainability into a concurrent engineering environment

NASA Astrophysics Data System (ADS)

Phillips, Clifton B.; Peterson, Robert R.

1993-02-01

This paper describes the results of a reliability and maintainability study conducted at the University of California, San Diego and supported by private industry. Private industry thought the study was important and provided the university access to innovative tools under cooperative agreement. The current capability of reliability and maintainability tools and how they fit into the design process is investigated. The evolution of design methodologies leading up to today's capability is reviewed for ways to enhance the design process while keeping cost under control. A method for measuring the consequences of reliability and maintainability policy for design configurations in an electronic environment is provided. The interaction of selected modern computer tool sets is described for reliability, maintainability, operations, and other elements of the engineering design process. These tools provide a robust system evaluation capability that brings life cycle performance improvement information to engineers and their managers before systems are deployed, and allow them to monitor and track performance while it is in operation.

Designing With Empathy: Humanizing Narratives for Inspired Healthcare Experiences.

PubMed

Carmel-Gilfilen, Candy; Portillo, Margaret

2016-01-01

Designers can and should play a critical role in shaping a holistic healthcare experience by creating empathetic design solutions that foster a culture of care for patients, families, and staff. Using narrative inquiry as a design tool, this case study shares strategies for promoting empathy. Designing for patient-centered care infuses empathy into the creative process. Narrative inquiry offers a methodology to think about and create empathetic design that enhances awareness, responsiveness, and accountability. This article shares discoveries from a studio on empathetic design within an outpatient cancer care center. The studio engaged students in narrative techniques throughout the design process by incorporating aural, visual, and written storytelling. Benchmarking, observations, and interviews were merged with data drawn from scholarly evidence-based design literature reviews. Using an empathy-focused design process not only motivated students to be more engaged in the project but facilitated the generation of fresh and original ideas. Design solutions were innovative and impactful in supporting the whole person. Similarities as well as differences defined empathetic cancer care across projects and embodied concepts of design empowerment, design for the whole person, and design for healing. By becoming more conscious of empathy, those who create healthcare environments can better connect holistically to the user to take an experiential approach to design. Explicitly developing a mind-set that raises empathy to the forefront of the design process offers a breakthrough in design thinking that bridges the gap between what might be defined as "good design" and patient-centered care. © The Author(s) 2015.

Optimal cost design of water distribution networks using a decomposition approach

NASA Astrophysics Data System (ADS)

Lee, Ho Min; Yoo, Do Guen; Sadollah, Ali; Kim, Joong Hoon

2016-12-01

Water distribution network decomposition, which is an engineering approach, is adopted to increase the efficiency of obtaining the optimal cost design of a water distribution network using an optimization algorithm. This study applied the source tracing tool in EPANET, which is a hydraulic and water quality analysis model, to the decomposition of a network to improve the efficiency of the optimal design process. The proposed approach was tested by carrying out the optimal cost design of two water distribution networks, and the results were compared with other optimal cost designs derived from previously proposed optimization algorithms. The proposed decomposition approach using the source tracing technique enables the efficient decomposition of an actual large-scale network, and the results can be combined with the optimal cost design process using an optimization algorithm. This proves that the final design in this study is better than those obtained with other previously proposed optimization algorithms.

Numerical aerodynamic simulation facility preliminary study, volume 2 and appendices

NASA Technical Reports Server (NTRS)

1977-01-01

Data to support results obtained in technology assessment studies are presented. Objectives, starting points, and future study tasks are outlined. Key design issues discussed in appendices include: data allocation, transposition network design, fault tolerance and trustworthiness, logic design, processing element of existing components, number of processors, the host system, alternate data base memory designs, number representation, fast div 521 instruction, architectures, and lockstep array versus synchronizable array machine comparison.

Schools Designed with Community Participation.

ERIC Educational Resources Information Center

Sanoff, Henry

This publication presents case studies of school buildings to demonstrate the application of a post occupancy evaluation (POE) during various stages of the design and planning process. It explains that because POE is a process for gathering information about a building in use, it can be applied effectively both to renovation and expansion projects…

Global Explorers: An Examination of Program Processes and Outcomes

ERIC Educational Resources Information Center

Duerden, Mathew David

2009-01-01

This study utilizes longitudinal, mixed-method data drawn from participants in an environmental education/international immersion program for middle high-school students to study outcomes and processes associated with program participation. Studies of program outcomes and processes are important for better understanding the design and impact of…

Pilot scale system for the production of palm-based Monoester-OH

NASA Astrophysics Data System (ADS)

Ngah, Muhammad Syukri; Badri, Khairiah Haji

2016-11-01

A mechanically agitate reactor vessel in a moderate scale size of 500 L has been developed. This vessel was constructed to produce palm-based polyurethane polyol with a capacity of maximum 400 L. This is to accomodate the demand required for marketing trial run as part of the commercialization intention. The chemistry background of the process design was thoroughly studied. The esterification and condensation in batch process was maintained from the laboratory scale. Only RBD palm kernel oil was used in this study. This paper will describe the engineering design for the reactor vessel development beginning at the stoichiometric equations for the production process to the detail engineering including the equipment selection and fabrication in order to meet the design and objective specifications.

Lubricant based determination of design space for continuously manufactured high dose paracetamol tablets.

PubMed

Taipale-Kovalainen, Krista; Karttunen, Anssi-Pekka; Ketolainen, Jarkko; Korhonen, Ossi

2018-03-30

The objective of this study was to devise robust and stable continuous manufacturing process settings, by exploring the design space after an investigation of the lubrication-based parameters influencing the continuous direct compression tableting of high dose paracetamol tablets. Experimental design was used to generate a structured study plan which involved 19 runs. The formulation variables studied were the type of lubricant (magnesium stearate or stearic acid) and its concentration (0.5, 1.0 and 1.5%). Process variables were total production feed rate (5, 10.5 and 16kg/h), mixer speed rpm (500, 850 and 1200rpm), and mixer inlet port for lubricant (A or B). The continuous direct compression tableting line consisted of loss-in-weight feeders, a continuous mixer and a tablet press. The Quality Target Product Profile (QTPP) was defined for the final product, as the flowability of powder blends (2.5s), tablet strength (147N), dissolution in 2.5min (90%) and ejection force (425N). A design space was identified which fulfilled all the requirements of QTPP. The type and concentration of lubricant exerted the greatest influence on the design space. For example, stearic acid increased the tablet strength. Interestingly, the studied process parameters had only a very minor effect on the quality of the final product and the design space. It is concluded that the continuous direct compression tableting process itself is insensitive and can cope with changes in lubrication, whereas formulation parameters exert a major influence on the end product quality. Copyright © 2017 Elsevier B.V. All rights reserved.

Process innovation in high-performance systems: From polymeric composites R&D to design and build of airplane showers

NASA Astrophysics Data System (ADS)

Wu, Yi-Jui

In the aerospace industry reducing aircraft weight is key because it increases flight performance and drives down operating costs. With fierce competition in the commercial aircraft industry, companies that focused primarily on exterior aircraft performance design issues are turning more attention to the design of aircraft interior. Simultaneously, there has been an increase in the number of new amenities offered to passengers especially in first class travel and executive jets. These new amenities present novel and challenging design parameters that include integration into existing aircraft systems without sacrificing flight performance. The objective of this study was to design a re-circulating shower system for an aircraft that weighs significantly less than pre-existing shower designs. This was accomplished by integrating processes from polymeric composite materials, water filtration, and project management. Carbon/epoxy laminates exposed to hygrothermal cycling conditions were evaluated and compared to model calculations. Novel materials and a variety of fabrication processes were developed to create new types of paper for honeycomb applications. Experiments were then performed on the properties and honeycomb processability of these new papers. Standard water quality tests were performed on samples taken from the re-circulating system to see if current regulatory standards were being met. These studies were executed and integrated with tools from project management to design a better shower system for commercial aircraft applications.

A self-study of designing and implementing an inquiry-based chemistry course for elementary education majors

NASA Astrophysics Data System (ADS)

Larson, Teresa

2011-12-01

This self-study examines my experiences with implementing an inquiry-based version of a chemistry course (Chemistry 299) designed for elementary education majors. The inquiry-based curriculum design and teaching strategies that I implement in Chemistry 299 is the focus of this study. Since my previous education and professional experiences were in the physical sciences, I position myself in this study as a scientist who engages in self-study as a form of professional development for the purpose of developing an inquiry-based curriculum and instructional practices. My research provides an inside perspective of the curriculum development process. This process involves implementing the inquiry-oriented ideas and knowledge I acquired in my graduate studies to design the curriculum and influence my teaching practice. My analysis of the curriculum and my instruction is guided by two questions: What are the strengths and weaknesses of the inquiry-based Chemistry 299 curriculum design? What does the process of developing my inquiry-based teaching practice entail and what makes is challenging? Schwab's (1973) The Practical 3: Translation into Curriculum serves as the theoretical framework for this study because of the emphasis Schwab places on combining theoretical and practical knowledge in the curriculum development process and because of the way he characterizes the curriculum. The findings in this study are separated into curriculum and instruction domains. First, the Chemistry 299 curriculum was designed to make the epistemological practices of scientists "accessible" to students by emphasizing epistemic development with respect to their ideas about scientific inquiry and science learning. Using student learning as a gauge for progress, I identify specific design elements that developed transferable inquiry skills as a means to support scientific literacy and pre-service teacher education. Second, the instruction-related findings built upon the insight I gained through my analysis of the curriculum. The data reveals four areas of inner conflict I dealt with throughout the study that related to underlying beliefs I held about science teaching and learning. The implications of the study position the Chemistry 299 curriculum in the field and speak to issues related to developing science courses for elementary education majors and professional development for scientists.

Warpage analysis in injection moulding process

NASA Astrophysics Data System (ADS)

Hidayah, M. H. N.; Shayfull, Z.; Nasir, S. M.; Fathullah, M.; Hazwan, M. H. M.

2017-09-01

This study was concentrated on the effects of process parameters in plastic injection moulding process towards warpage problem by using Autodesk Moldflow Insight (AMI) software for the simulation. In this study, plastic dispenser of dental floss has been analysed with thermoplastic material of Polypropylene (PP) used as the moulded material and details properties of 80 Tonne Nessei NEX 1000 injection moulding machine also has been used in this study. The variable parameters of the process are packing pressure, packing time, melt temperature and cooling time. Minimization of warpage obtained from the optimization and analysis data from the Design Expert software. Integration of Response Surface Methodology (RSM), Center Composite Design (CCD) with polynomial models that has been obtained from Design of Experiment (DOE) is the method used in this study. The results show that packing pressure is the main factor that will contribute to the formation of warpage in x-axis and y-axis. While in z-axis, the main factor is melt temperature and packing time is the less significant among the four parameters in x, y and z-axes. From optimal processing parameter, the value of warpage in x, y and z-axis have been optimised by 21.60%, 26.45% and 24.53%, respectively.

Adapting Rational Unified Process (RUP) approach in designing a secure e-Tendering model

NASA Astrophysics Data System (ADS)

Mohd, Haslina; Robie, Muhammad Afdhal Muhammad; Baharom, Fauziah; Darus, Norida Muhd; Saip, Mohamed Ali; Yasin, Azman

2016-08-01

e-Tendering is an electronic processing of the tender document via internet and allow tenderer to publish, communicate, access, receive and submit all tender related information and documentation via internet. This study aims to design the e-Tendering system using Rational Unified Process approach. RUP provides a disciplined approach on how to assign tasks and responsibilities within the software development process. RUP has four phases that can assist researchers to adjust the requirements of various projects with different scope, problem and the size of projects. RUP is characterized as a use case driven, architecture centered, iterative and incremental process model. However the scope of this study only focusing on Inception and Elaboration phases as step to develop the model and perform only three of nine workflows (business modeling, requirements, analysis and design). RUP has a strong focus on documents and the activities in the inception and elaboration phases mainly concern the creation of diagrams and writing of textual descriptions. The UML notation and the software program, Star UML are used to support the design of e-Tendering. The e-Tendering design based on the RUP approach can contribute to e-Tendering developers and researchers in e-Tendering domain. In addition, this study also shows that the RUP is one of the best system development methodology that can be used as one of the research methodology in Software Engineering domain related to secured design of any observed application. This methodology has been tested in various studies in certain domains, such as in Simulation-based Decision Support, Security Requirement Engineering, Business Modeling and Secure System Requirement, and so forth. As a conclusion, these studies showed that the RUP one of a good research methodology that can be adapted in any Software Engineering (SE) research domain that required a few artifacts to be generated such as use case modeling, misuse case modeling, activity diagram, and initial class diagram from a list of requirements as identified earlier by the SE researchers

Conducting Research in Technical Communication: The Application of True Experimental Designs.

ERIC Educational Resources Information Center

Spyridakis, Jan H.

1992-01-01

Explains the use of true experimental designs in technical communication research, lists the eight steps in the research process, and concludes with the hope that practitioners should now be able to read research studies critically and perhaps design empirical studies of their own after further reading. (SR)

Exploring Collaboration in Learning by Design via Weblogs

ERIC Educational Resources Information Center

Çakiroglu, Ünal; Yildiz, Merve; Mazlum, Ebru; Turan Güntepe, Ebru; Aydin, Senay

2017-01-01

The purpose of this qualitative study was to explore collaborative activities that were carried out via weblogs according to a "learning by design" approach. During the instructional process, Microsoft Publisher was used for a series of infographic design activities. The study participants were 33 undergraduate students who were enrolled…

Training Students’ Science Process Skills through Didactic Design on Work and Energy

NASA Astrophysics Data System (ADS)

Ramayanti, S.; Utari, S.; Saepuzaman, D.

2017-09-01

Science Process Skills (SPS) has not been optimally trained to the students in the learning activity. The aim of this research is finding the ways to train SPS on the subject of Work and Energy. One shot case study design is utilized in this research that conducted on 32 students in one of the High Schools in Bandung. The students’ SPS responses were analyzed by the development SPS based assessment portfolios. The results of this research showed the didactic design that had been designed to training the identifying variables skills, formulating hypotheses, and the experiment activity shows the development. But the didactic design to improve the students’ predicting skills shows that the development is still not optimal. Therefore, in the future studies need to be developed the didactic design on the subject Work and Energy that exercising these skills.

GIS-assisted spatial analysis for urban regulatory detailed planning: designer's dimension in the Chinese code system

NASA Astrophysics Data System (ADS)

Yu, Yang; Zeng, Zheng

2009-10-01

By discussing the causes behind the high amendments ratio in the implementation of urban regulatory detailed plans in China despite its law-ensured status, the study aims to reconcile conflict between the legal authority of regulatory detailed planning and the insufficient scientific support in its decision-making and compilation by introducing into the process spatial analysis based on GIS technology and 3D modeling thus present a more scientific and flexible approach to regulatory detailed planning in China. The study first points out that the current compilation process of urban regulatory detailed plan in China employs mainly an empirical approach which renders it constantly subjected to amendments; the study then discusses the need and current utilization of GIS in the Chinese system and proposes the framework of a GIS-assisted 3D spatial analysis process from the designer's perspective which can be regarded as an alternating processes between the descriptive codes and physical design in the compilation of regulatory detailed planning. With a case study of the processes and results from the application of the framework, the paper concludes that the proposed framework can be an effective instrument which provides more rationality, flexibility and thus more efficiency to the compilation and decision-making process of urban regulatory detailed plan in China.

The Value of the Operational Principle in Instructional Design

ERIC Educational Resources Information Center

Gibbons, Andrew S.

2009-01-01

Formal design studies are increasing our insight into design processes, including those of instructional design. Lessons are being learned from other design fields, and new techniques and concepts can be imported as they are demonstrated effective. The purpose of this article is to introduce a design concept--the "operational principle"--for…

Learning from the Pros: How Experienced Designers Translate Instructional Design Models into Practice

ERIC Educational Resources Information Center

Ertmer, Peggy A.; York, Cindy S.; Gedik, Nuray

2009-01-01

Understanding how experienced designers approach complex design problems provides new perspectives on how they translate instructional design (ID) models and processes into practice. In this article, the authors describe the results of a study in which 16 "seasoned" designers shared compelling stories from practice that offered insights into their…

Cognitive Activity-based Design Methodology for Novice Visual Communication Designers

ERIC Educational Resources Information Center

Kim, Hyunjung; Lee, Hyunju

2016-01-01

The notion of design thinking is becoming more concrete nowadays, as design researchers and practitioners study the thinking processes involved in design and employ the concept of design thinking to foster better solutions to complex and ill-defined problems. The goal of the present research is to develop a cognitive activity-based design…

Application of quality by design concept to develop a dual gradient elution stability-indicating method for cloxacillin forced degradation studies using combined mixture-process variable models.

PubMed

Zhang, Xia; Hu, Changqin

2017-09-08

Penicillins are typical of complex ionic samples which likely contain large number of degradation-related impurities (DRIs) with different polarities and charge properties. It is often a challenge to develop selective and robust high performance liquid chromatography (HPLC) methods for the efficient separation of all DRIs. In this study, an analytical quality by design (AQbD) approach was proposed for stability-indicating method development of cloxacillin. The structures, retention and UV characteristics rules of penicillins and their impurities were summarized and served as useful prior knowledge. Through quality risk assessment and screen design, 3 critical process parameters (CPPs) were defined, including 2 mixture variables (MVs) and 1 process variable (PV). A combined mixture-process variable (MPV) design was conducted to evaluate the 3 CPPs simultaneously and a response surface methodology (RSM) was used to achieve the optimal experiment parameters. A dual gradient elution was performed to change buffer pH, mobile-phase type and strength simultaneously. The design spaces (DSs) was evaluated using Monte Carlo simulation to give their possibility of meeting the specifications of CQAs. A Plackett-Burman design was performed to test the robustness around the working points and to decide the normal operating ranges (NORs). Finally, validation was performed following International Conference on Harmonisation (ICH) guidelines. To our knowledge, this is the first study of using MPV design and dual gradient elution to develop HPLC methods and improve separations for complex ionic samples. Copyright © 2017 Elsevier B.V. All rights reserved.

Total-System Approach To Design And Analysis Of Structures

NASA Technical Reports Server (NTRS)

Verderaime, V.

1995-01-01

Paper presents overview and study of, and comprehensive approach to, multidisciplinary engineering design and analysis of structures. Emphasizes issues related to design of semistatic structures in environments in which spacecraft launched, underlying concepts applicable to other structures within unique terrestrial, marine, or flight environments. Purpose of study to understand interactions among traditionally separate engineering design disciplines with view toward optimizing not only structure but also overall design process.

System Identification of a Heaving Point Absorber: Design of Experiment and Device Modeling

DOE PAGES

Bacelli, Giorgio; Coe, Ryan; Patterson, David; ...

2017-04-01

Empirically based modeling is an essential aspect of design for a wave energy converter. These models are used in structural, mechanical and control design processes, as well as for performance prediction. The design of experiments and methods used to produce models from collected data have a strong impact on the quality of the model. This study considers the system identification and model validation process based on data collected from a wave tank test of a model-scale wave energy converter. Experimental design and data processing techniques based on general system identification procedures are discussed and compared with the practices often followedmore » for wave tank testing. The general system identification processes are shown to have a number of advantages. The experimental data is then used to produce multiple models for the dynamics of the device. These models are validated and their performance is compared against one and other. Furthermore, while most models of wave energy converters use a formulation with wave elevation as an input, this study shows that a model using a hull pressure sensor to incorporate the wave excitation phenomenon has better accuracy.« less

System Identification of a Heaving Point Absorber: Design of Experiment and Device Modeling

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bacelli, Giorgio; Coe, Ryan; Patterson, David

Empirically based modeling is an essential aspect of design for a wave energy converter. These models are used in structural, mechanical and control design processes, as well as for performance prediction. The design of experiments and methods used to produce models from collected data have a strong impact on the quality of the model. This study considers the system identification and model validation process based on data collected from a wave tank test of a model-scale wave energy converter. Experimental design and data processing techniques based on general system identification procedures are discussed and compared with the practices often followedmore » for wave tank testing. The general system identification processes are shown to have a number of advantages. The experimental data is then used to produce multiple models for the dynamics of the device. These models are validated and their performance is compared against one and other. Furthermore, while most models of wave energy converters use a formulation with wave elevation as an input, this study shows that a model using a hull pressure sensor to incorporate the wave excitation phenomenon has better accuracy.« less

Electricity pricing policy: A neo-institutional, developmental and cross-national policy design map

NASA Astrophysics Data System (ADS)

Koundinya, Sridarshan Umesh

This dissertation explores the role of ideas and ideology in the mental policy design maps of regulators in the US and in India. The research approach is to describe the regulatory design process in the history of the US electric industry from a neo-institutional and developmental perspective. And then to use the insights of such a study to suggest policy options to a sample of Indian experts. A regulatory process model explores the interactions among normative values, regulatory instruments and historical phases in policy design. A spectrum of seven regulatory instruments--subsidized rates, average cost pricing, marginal cost pricing, time-of-use pricing, ramsey pricing, incentive regulation and spot pricing is examined. A neo-institutional perspective characterizes the process of institutionalizing these regulatory instruments as a design process that infuses them with values beyond mere technical requirements. The process model includes normative values such as efficiency, fairness, free choice and political feasibility. These values arise from an analytical classification of various market metaphors debated in the history of economic thought. The theory of development and co-evolution applied to the history of electricity regulation yields a typology of evolutionary phases in the US. The typology describes hierarchically emergent relationships between supply and demand and among the normative values. The theory hypothesizes technologically contingent relationships between pricing policies and normative values in the historical phases of dependence (or rural), independence (or urban) and interdependence (or informational). The contents of this model are represented as related elements in a policy design map that simplifies the process of designing regulatory instruments in the US. This neo-institutional, developmental policy design map was used to design a survey instrument. The survey was conducted among electricity experts in India to test the hypothesized inter-relationships among various elements at different levels of the policy design map in a cross-national context. The study adds value with a comprehensive design map that helps to organize and give coherence to the policy prescriptions made by Indian experts as they converge on one institutional model. Thus the dissertation contributes to the transfer of knowledge about regulatory practice from the US to India.

How to Construct a Mixed Methods Research Design.

PubMed

Schoonenboom, Judith; Johnson, R Burke

2017-01-01

This article provides researchers with knowledge of how to design a high quality mixed methods research study. To design a mixed study, researchers must understand and carefully consider each of the dimensions of mixed methods design, and always keep an eye on the issue of validity. We explain the seven major design dimensions: purpose, theoretical drive, timing (simultaneity and dependency), point of integration, typological versus interactive design approaches, planned versus emergent design, and design complexity. There also are multiple secondary dimensions that need to be considered during the design process. We explain ten secondary dimensions of design to be considered for each research study. We also provide two case studies showing how the mixed designs were constructed.

Designing visual displays and system models for safe reactor operations based on the user`s perspective of the system

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brown-VanHoozer, S.A.

Most designers are not schooled in the area of human-interaction psychology and therefore tend to rely on the traditional ergonomic aspects of human factors when designing complex human-interactive workstations related to reactor operations. They do not take into account the differences in user information processing behavior and how these behaviors may affect individual and team performance when accessing visual displays or utilizing system models in process and control room areas. Unfortunately, by ignoring the importance of the integration of the user interface at the information process level, the result can be sub-optimization and inherently error- and failure-prone systems. Therefore, tomore » minimize or eliminate failures in human-interactive systems, it is essential that the designers understand how each user`s processing characteristics affects how the user gathers information, and how the user communicates the information to the designer and other users. A different type of approach in achieving this understanding is Neuro Linguistic Programming (NLP). The material presented in this paper is based on two studies involving the design of visual displays, NLP, and the user`s perspective model of a reactor system. The studies involve the methodology known as NLP, and its use in expanding design choices from the user`s ``model of the world,`` in the areas of virtual reality, workstation design, team structure, decision and learning style patterns, safety operations, pattern recognition, and much, much more.« less

A Case Study on Collective Cognition and Operation in Team-Based Computer Game Design by Middle-School Children

ERIC Educational Resources Information Center

Ke, Fengfeng; Im, Tami

2014-01-01

This case study examined team-based computer-game design efforts by children with diverse abilities to explore the nature of their collective design actions and cognitive processes. Ten teams of middle-school children, with a high percentage of minority students, participated in a 6-weeks, computer-assisted math-game-design program. Essential…

The development and application of a multi-criteria optimization method to the design of a 20-seat regional jet airliner

NASA Astrophysics Data System (ADS)

Au, How Meng

The aircraft design process traditionally starts with a given set of top-level requirements. These requirements can be aircraft performance related such as the fuel consumption, cruise speed, or takeoff field length, etc., or aircraft geometry related such as the cabin height or cabin volume, etc. This thesis proposes a new aircraft design process in which some of the top-level requirements are not explicitly specified. Instead, these previously specified parameters are now determined through the use of the Price-Per-Value-Factor (PPVF) index. This design process is well suited for design projects where general consensus of the top-level requirements does not exist. One example is the design of small commuter airliners. The above mentioned value factor is comprised of productivity, cabin volume, cabin height, cabin pressurization, mission fuel consumption, and field length, each weighted to a different exponent. The relative magnitude and positive/negative signs of these exponents are in agreement with general experience. The value factors of the commuter aircraft are shown to have improved over a period of four decades. In addition, the purchase price is shown to vary linearly with the value factor. The initial aircraft sizing process can be manpower intensive if the calculations are done manually. By incorporating automation into the process, the design cycle can be shortened considerably. The Fortran program functions and subroutines in this dissertation, in addition to the design and optimization methodologies described above, contribute to the reduction of manpower required for the initial sizing process. By combining the new design process mentioned above and the PPVF as the objective function, an optimization study is conducted on the design of a 20-seat regional jet. Handbook methods for aircraft design are written into a Fortran code. A genetic algorithm is used as the optimization scheme. The result of the optimization shows that aircraft designed to this PPVF index can be competitive compared to existing turboprop commuter aircraft. The process developed can be applied to other classes of aircraft with the designer modifying the cost function based upon the design goals.

Using an Analogical Thinking Model as an Instructional Tool to Improve Student Cognitive Ability in Architecture Design Learning Process

ERIC Educational Resources Information Center

Wu, Yun-Wu; Weng, Kuo-Hua

2013-01-01

Lack of creativity is a problem often plaguing students from design-related departments. Therefore, this study is intended to incorporate analogical thinking in the education of architecture design to enhance students' learning and their future career performance. First, this study explores the three aspects of architecture design curricula,…

Cognitive Task Analysis of Experts in Designing Multimedia Learning Object Guideline (M-LOG)

ERIC Educational Resources Information Center

Razak, Rafiza Abdul; Palanisamy, Punithavathy

2013-01-01

The purpose of this study was to design and develop a set of guidelines for multimedia learning objects to inform instructional designers (IDs) about the procedures involved in the process of content analysis. This study was motivated by the absence of standardized procedures in the beginning phase of the multimedia learning object design which is…

Bridging CALL & HCI: Input from Participatory Design

ERIC Educational Resources Information Center

Cardenas-Claros, Monica S.; Gruba, Paul A.

2010-01-01

Participatory design (PD), or the collaboration between software engineers and end users throughout the design process, may help improve CALL design practices. In this case study, four ESL learners, a software designer, and a language teacher created and evaluated a series of paper prototypes concerning help options in computer-based second…

High School Student Information Access and Engineering Design Performance

ERIC Educational Resources Information Center

Mentzer, Nathan

2014-01-01

Developing solutions to engineering design problems requires access to information. Research has shown that appropriately accessing and using information in the design process improves solution quality. This quasi-experimental study provides two groups of high school students with a design problem in a three hour design experience. One group has…

An Interactive Preliminary Design System of High Speed Forebody and Inlet Flows

NASA Technical Reports Server (NTRS)

Liou, May-Fun; Benson, Thomas J.; Trefny, Charles J.

2010-01-01

This paper demonstrates a simulation-based aerodynamic design process of high speed inlet. A genetic algorithm is integrated into the design process to facilitate the single objective optimization. The objective function is the total pressure recovery and is obtained by using a PNS solver for its computing efficiency. The system developed uses existing software of geometry definition, mesh generation and CFD analysis. The process which produces increasingly desirable design in each genetic evolution over many generations is automatically carried out. A generic two-dimensional inlet is created as a showcase to demonstrate the capabilities of this tool. A parameterized study of geometric shape and size of the showcase is also presented.

Overview of the Dissertation Process within the Framework of Flow Theory: A Qualitative Study

ERIC Educational Resources Information Center

Cakmak, Esra; Oztekin, Ozge; Isci, Sabiha; Danisman, Sahin; Uslu, Fatma; Karadag, Engin

2015-01-01

The purpose of this study is to examine the flow of doctoral students who are also research assistants and in the dissertation process. The study was designed using the case study method. The case undertaken in the study was the dissertation process. Eleven participants were selected into the study using maximum variation sampling. Face-to-face,…

Designing persuasive health materials using processing fluency: a literature review.

PubMed

Okuhara, Tsuyoshi; Ishikawa, Hirono; Okada, Masahumi; Kato, Mio; Kiuchi, Takahiro

2017-06-08

Health materials to promote health behaviors should be readable and generate favorable evaluations of the message. Processing fluency (the subjective experience of ease with which people process information) has been increasingly studied over the past decade. In this review, we explore effects and instantiations of processing fluency and discuss the implications for designing effective health materials. We searched seven online databases using "processing fluency" as the key word. In addition, we gathered relevant publications using reference snowballing. We included published records that were written in English and applicable to the design of health materials. We found 40 articles that were appropriate for inclusion. Various instantiations of fluency have a uniform effect on human judgment: fluently processed stimuli generate positive judgments (e.g., liking, confidence). Processing fluency is used to predict the effort needed for a given task; accordingly, it has an impact on willingness to undertake the task. Physical perceptual, lexical, syntactic, phonological, retrieval, and imagery fluency were found to be particularly relevant to the design of health materials. Health-care professionals should consider the use of a perceptually fluent design, plain language, numeracy with an appropriate degree of precision, a limited number of key points, and concrete descriptions that make recipients imagine healthy behavior. Such fluently processed materials that are easy to read and understand have enhanced perspicuity and persuasiveness.

Product and Process Perspectives: an Empirical Study of Explicitation in Chinese-English Translation

ERIC Educational Resources Information Center

Fan, Zhewei

2012-01-01

Product-and process-oriented, this dissertation focuses on both the explicitness in translated texts and the implementation of explicitation in Chinese-English translation. In doing so, it provides a new cognitive framework for understanding explicitation as a strategic process. A specially designed study of the translation process facilitates the…

A method of network topology optimization design considering application process characteristic

NASA Astrophysics Data System (ADS)

Wang, Chunlin; Huang, Ning; Bai, Yanan; Zhang, Shuo

2018-03-01

Communication networks are designed to meet the usage requirements of users for various network applications. The current studies of network topology optimization design mainly considered network traffic, which is the result of network application operation, but not a design element of communication networks. A network application is a procedure of the usage of services by users with some demanded performance requirements, and has obvious process characteristic. In this paper, we first propose a method to optimize the design of communication network topology considering the application process characteristic. Taking the minimum network delay as objective, and the cost of network design and network connective reliability as constraints, an optimization model of network topology design is formulated, and the optimal solution of network topology design is searched by Genetic Algorithm (GA). Furthermore, we investigate the influence of network topology parameter on network delay under the background of multiple process-oriented applications, which can guide the generation of initial population and then improve the efficiency of GA. Numerical simulations show the effectiveness and validity of our proposed method. Network topology optimization design considering applications can improve the reliability of applications, and provide guidance for network builders in the early stage of network design, which is of great significance in engineering practices.

Does Implementation Follow Design? A Case Study of a Workplace Health Promotion Program Using the 4-S Program Design and the PIPE Impact Metric Evaluation Models.

PubMed

Äikäs, Antti Hermanni; Pronk, Nicolaas P; Hirvensalo, Mirja Hannele; Absetz, Pilvikki

2017-08-01

The aim of this study was to describe the content of a multiyear market-based workplace health promotion (WHP) program and to evaluate design and implementation processes in a real-world setting. Data was collected from the databases of the employer and the service provider. It was classified using the 4-S (Size, Scope, Scalability, and Sustainability) and PIPE Impact Metric (Penetration, Implementation) models. Data analysis utilized both qualitative and quantitative methods. Program design covered well the evidence-informed best practices except for clear path toward sustainability, cooperation with occupational health care, and support from middle-management supervisors. The penetration rate among participants was high (99%) and majority (81%) of services were implemented as designed. Study findings indicate that WHP market would benefit the use of evidence-based design principles and tendentious decisions to anticipate a long-term implementation process already during the planning phase.

Does Implementation Follow Design? A Case Study of a Workplace Health Promotion Program Using the 4-S Program Design and the PIPE Impact Metric Evaluation Models

PubMed Central

Äikäs, Antti Hermanni; Pronk, Nicolaas P.; Hirvensalo, Mirja Hannele; Absetz, Pilvikki

2017-01-01

Objective: The aim of this study was to describe the content of a multiyear market-based workplace health promotion (WHP) program and to evaluate design and implementation processes in a real-world setting. Methods: Data was collected from the databases of the employer and the service provider. It was classified using the 4-S (Size, Scope, Scalability, and Sustainability) and PIPE Impact Metric (Penetration, Implementation) models. Data analysis utilized both qualitative and quantitative methods. Results: Program design covered well the evidence-informed best practices except for clear path toward sustainability, cooperation with occupational health care, and support from middle-management supervisors. The penetration rate among participants was high (99%) and majority (81%) of services were implemented as designed. Conclusion: Study findings indicate that WHP market would benefit the use of evidence-based design principles and tendentious decisions to anticipate a long-term implementation process already during the planning phase. PMID:28665839

Design of a Model Execution Framework: Repetitive Object-Oriented Simulation Environment (ROSE)

NASA Technical Reports Server (NTRS)

Gray, Justin S.; Briggs, Jeffery L.

2008-01-01

The ROSE framework was designed to facilitate complex system analyses. It completely divorces the model execution process from the model itself. By doing so ROSE frees the modeler to develop a library of standard modeling processes such as Design of Experiments, optimizers, parameter studies, and sensitivity studies which can then be applied to any of their available models. The ROSE framework accomplishes this by means of a well defined API and object structure. Both the API and object structure are presented here with enough detail to implement ROSE in any object-oriented language or modeling tool.

A Comparative Study : Microprogrammed Vs Risc Architectures For Symbolic Processing

NASA Astrophysics Data System (ADS)

Heudin, J. C.; Metivier, C.; Demigny, D.; Maurin, T.; Zavidovique, B.; Devos, F.

1987-05-01

It is oftenclaimed that conventional computers are not well suited for human-like tasks : Vision (Image Processing), Intelligence (Symbolic Processing) ... In the particular case of Artificial Intelligence, dynamic type-checking is one example of basic task that must be improved. The solution implemented in most Lisp work-stations consists in a microprogrammed architecture with a tagged memory. Another way to gain efficiency is to design a well suited instruction set for symbolic processing, which reduces the semantic gap between the high level language and the machine code. In this framework, the RISC concept provides a convenient approach to study new architectures for symbolic processing. This paper compares both approaches and describes our projectof designing a compact symbolic processor for Artificial Intelligence applications.

Supporting BPMN choreography with system integration artefacts for enterprise process collaboration

NASA Astrophysics Data System (ADS)

Nie, Hongchao; Lu, Xudong; Duan, Huilong

2014-07-01

Business Process Model and Notation (BPMN) choreography modelling depicts externally visible message exchanges between collaborating processes of enterprise information systems. Implementation of choreography relies on designing system integration solutions to realise message exchanges between independently developed systems. Enterprise integration patterns (EIPs) are widely accepted artefacts to design integration solutions. If the choreography model represents coordination requirements between processes with behaviour mismatches, the integration designer needs to analyse the routing requirements and address these requirements by manually designing EIP message routers. As collaboration scales and complexity increases, manual design becomes inefficient. Thus, the research problem of this paper is to explore a method to automatically identify routing requirements from BPMN choreography model and to accordingly design routing in the integration solution. To achieve this goal, recurring behaviour mismatch scenarios are analysed as patterns, and corresponding solutions are proposed as EIP routers. Using this method, a choreography model can be analysed by computer to identify occurrences of mismatch patterns, leading to corresponding router selection. A case study demonstrates that the proposed method enables computer-assisted integration design to implement choreography. A further experiment reveals that the method is effective to improve the design quality and reduce time cost.

Programming and machining of complex parts based on CATIA solid modeling

NASA Astrophysics Data System (ADS)

Zhu, Xiurong

2017-09-01

The complex parts of the use of CATIA solid modeling programming and simulation processing design, elaborated in the field of CNC machining, programming and the importance of processing technology. In parts of the design process, first make a deep analysis on the principle, and then the size of the design, the size of each chain, connected to each other. After the use of backstepping and a variety of methods to calculate the final size of the parts. In the selection of parts materials, careful study, repeated testing, the final choice of 6061 aluminum alloy. According to the actual situation of the processing site, it is necessary to make a comprehensive consideration of various factors in the machining process. The simulation process should be based on the actual processing, not only pay attention to shape. It can be used as reference for machining.

The implementation of the integrated design process in the hole-plan system

NASA Astrophysics Data System (ADS)

Ruy, Won-Sun; Ko, Dae-Eun; Yang, Young-Soon

2012-12-01

All current shipyards are using the customized CAD/CAM programs in order to improve the design quality and increase the design efficiency. Even though the data structures for ship design and construction are almost completed, the implementation related to the ship design processes are still in progress so that it has been the main causes of the bottleneck and delay during the middle of design process. In this study, we thought that the hole-plan system would be a good example which is remained to be improved. The people of outfitting division who don't have direct authority to edit the structural panels, should request the hull design division to install the holes for the outfitting equipment. For acceptance, they should calculate the hole position, determine the hole type, and find the intersected contour of panel. After consideration of the hull people, the requested holes are manually installed on the hull structure. As the above, many processes are needed such as communication and discussion between the divisions, drawings for hole-plan, and the consideration for the structural or production compatibility. However this iterative process takes a lot of working time and requires mental pressure to the related people and cross-division conflict. This paper will handle the hole-plan system in detail to automate the series of process and minimize the human efforts and time-consumption.

Carbon dioxide mineralization process design and evaluation: concepts, case studies, and considerations.

PubMed

Yuen, Yeo Tze; Sharratt, Paul N; Jie, Bu

2016-11-01

Numerous carbon dioxide mineralization (CM) processes have been proposed to overcome the slow rate of natural weathering of silicate minerals. Ten of these proposals are mentioned in this article. The proposals are described in terms of the four major areas relating to CM process design: pre-treatment, purification, carbonation, and reagent recycling operations. Any known specifics based on probable or representative operating and reaction conditions are listed, and basic analysis of the strengths and shortcomings associated with the individual process designs are given in this article. The processes typically employ physical or chemical pseudo-catalytic methods to enhance the rate of carbon dioxide mineralization; however, both methods have its own associated advantages and problems. To examine the feasibility of a CM process, three key aspects should be included in the evaluation criteria: energy use, operational considerations as well as product value and economics. Recommendations regarding the optimal level of emphasis and implementation of measures to control these aspects are given, and these will depend very much on the desired process objectives. Ultimately, a mix-and-match approach to process design might be required to provide viable and economic proposals for CM processes.

Optimal cure cycle design of a resin-fiber composite laminate

NASA Technical Reports Server (NTRS)

Hou, Jean W.; Sheen, Jeenson

1987-01-01

A unified computed aided design method was studied for the cure cycle design that incorporates an optimal design technique with the analytical model of a composite cure process. The preliminary results of using this proposed method for optimal cure cycle design are reported and discussed. The cure process of interest is the compression molding of a polyester which is described by a diffusion reaction system. The finite element method is employed to convert the initial boundary value problem into a set of first order differential equations which are solved simultaneously by the DE program. The equations for thermal design sensitivities are derived by using the direct differentiation method and are solved by the DE program. A recursive quadratic programming algorithm with an active set strategy called a linearization method is used to optimally design the cure cycle, subjected to the given design performance requirements. The difficulty of casting the cure cycle design process into a proper mathematical form is recognized. Various optimal design problems are formulated to address theses aspects. The optimal solutions of these formulations are compared and discussed.

Investigating Instructional Design Management and Leadership Competencies--A Delphi Study

ERIC Educational Resources Information Center

Gardner, Joel; Chongwony, Lewis; Washington, Tawana

2018-01-01

Research in instructional design and educational technology journals typically focuses on the theories, technologies, and processes related to practice of instructional design. There is little research emphasis, however, on leadership and management of instructional design in higher education. Investigating the competencies associated with…

Revision Vodcast Influence on Assessment Scores and Study Processes in Secondary Physics

ERIC Educational Resources Information Center

Marencik, Joseph J.

2012-01-01

A quasi-experimental switching replications design with matched participants was employed to determine the influence of revision vodcasts, or video podcasts, on students' assessment scores and study processes in secondary physics. This study satisfied a need for quantitative results in the area of vodcast influence on students' learning processes.…

Age and Visual Information Processing.

ERIC Educational Resources Information Center

Gummerman, Kent; And Others

This paper reports on three studies concerned with aspects of human visual information processing. Study I was an effort to measure the duration of iconic storage using a partial report method in children ranging in age from 6 to 13 years. Study II was designed to detect age related changes in the rate of processing (perceptually encoding) letters…

Designing and Proposing Your Research Project. Concise Guides to Conducting Behavioral, Health, and Social Science Research Series

ERIC Educational Resources Information Center

Urban, Jennifer Brown; van Eeden-Moorefield, Bradley Matheus

2017-01-01

Designing your own study and writing your research proposal takes time, often more so than conducting the study. This practical, accessible guide walks you through the entire process. You will learn to identify and narrow your research topic, develop your research question, design your study, and choose appropriate sampling and measurement…

Developing Tools to Counteract and Prevent Suicide Bomber Incidents: A Case Study in Value Sensitive Design.

PubMed

Royakkers, Lambèr; Steen, Marc

2017-08-01

Developers and designers make all sorts of moral decisions throughout an innovation project. In this article, we describe how teams of developers and designers engaged with ethics in the early phases of innovation based on case studies in the SUBCOP project (SUBCOP stands for 'SUicide Bomber COunteraction and Prevention'). For that purpose, Value Sensitive Design (VSD) will be used as a reference. Specifically, we focus on the following two research questions: How can researchers/developers learn about users' perspectives and values during the innovation process? and How can researchers/developers take into account these values, and related design criteria, in their decision-making during the innovation process? Based on a case study of several innovation processes in this project, we conclude the researchers/developers involved are able to do something similar to VSD (without them knowing about VSD or calling it 'VSD'), supported by relatively simple exercises in the project, e.g., meetings with potential end-users and discussions with members of the Ethical Advisory Board of the project. Furthermore, we also found-possibly somewhat counterintuitively-that a commercial, with its focus on understanding and satisfying customers' needs, can promote VSD.

Conceptual designs of NDA instruments for the NRTA system at the Rokkasho Reprocessing Plant

DOE Office of Scientific and Technical Information (OSTI.GOV)

Li, T.K.; Klosterbuer, S.F.; Menlove, H.O.

The authors are studying conceptual designs of selected nondestructive assay (NDA) instruments for the near-real-time accounting system at the rokkasho Reprocessing Plant (RRP) of Japan Nuclear Fuel Limited (JNFL). The JNFL RRP is a large-scale commercial reprocessing facility for spent fuel from boiling-water and pressurized-water reactors. The facility comprises two major components: the main process area to separate and produce purified plutonium nitrate and uranyl nitrate from irradiated reactor spent fuels, and the co-denitration process area to combine and convert the plutonium nitrate and uranyl nitrate into mixed oxide (MOX). The selected NDA instruments for conceptual design studies are themore » MOX-product canister counter, holdup measurement systems for calcination and reduction furnaces and for blenders in the co-denitration process, the isotope dilution gamma-ray spectrometer for the spent fuel dissolver solution, and unattended verification systems. For more effective and practical safeguards and material control and accounting at RRP, the authors are also studying the conceptual design for the UO{sub 3} large-barrel counter. This paper discusses the state-of-the-art NDA conceptual design and research and development activities for the above instruments.« less

Design, construction and calibration of a portable boundary layer wind tunnel for field use

USDA-ARS?s Scientific Manuscript database

Wind tunnels have been used for several decades to study wind erosion processes. Portable wind tunnels offer the advantage of testing natural surfaces in the field, but they must be carefully designed to insure that a logarithmic boundary layer is formed and that wind erosion processes may develop ...

Discussion of the Effectiveness of the National Accreditation Process of Secondary Science Education Programs

ERIC Educational Resources Information Center

Bazler, Judith A.; Van Sickle, Meta; Simonis, Doris; Graybill, Letty; Sorenson, Nancy; Brounstein, Erica

2014-01-01

This paper reflects upon the development, design, and results of a questionnaire distributed to professors of science education concerning the processes involved in a national accreditation of teacher education programs in science. After a pilot study, five professors/administrators from public and private institutions designed a questionnaire and…

The Self-Schedule System for Instructional-Learning Management in Adaptive School Learning Environments.

ERIC Educational Resources Information Center

Wang, Margaret C., Ed.

The studies in this monograph are designed to examine the implementation processes of an innovative instructional program and the relationship between the implementation process and the achievement of certain program goals in school settings. The monograph is a contribution to the technical aspects of designing and implementing innovative…

Designing a Flood-Risk Education Program in the Netherlands

ERIC Educational Resources Information Center

Bosschaart, Adwin; van der Schee, Joop; Kuiper, Wilmad

2016-01-01

This study focused on designing a flood-risk education program to enhance 15-year-old students' flood-risk perception. In the flood-risk education program, learning processes were modeled in such a way that the arousal of moderate levels of fear should prompt experiential and analytical information processing. In this way, understanding of flood…

Fostering Teachers' Design Expertise in Teacher Design Teams: Conducive Design and Support Activities

ERIC Educational Resources Information Center

Huizinga, Tjark; Handelzalts, Adam; Nieveen, Nienke; Voogt, Joke

2015-01-01

Supporting Teacher Design Teams (TDTs) during local curriculum development efforts is essential. To be able to provide high-quality support, insights are needed about how TDTs carry out design activities and how support is valued by the members of TDTs and how it affects their design expertise. In this study, the design and support processes of…

Optimization in the systems engineering process

NASA Technical Reports Server (NTRS)

Lemmerman, Loren A.

1993-01-01

The essential elements of the design process consist of the mission definition phase that provides the system requirements, the conceptual design, the preliminary design and finally the detailed design. Mission definition is performed largely by operations analysts in conjunction with the customer. The result of their study is handed off to the systems engineers for documentation as the systems requirements. The document that provides these requirements is the basis for the further design work of the design engineers at the Lockheed-Georgia Company. The design phase actually begins with conceptual design, which is generally conducted by a small group of engineers using multidisciplinary design programs. Because of the complexity of the design problem, the analyses are relatively simple and generally dependent on parametric analyses of the configuration. The result of this phase is a baseline configuration from which preliminary design may be initiated.

Methodological considerations for studying social processes.

PubMed

Patterson, Barbara; Morin, Karen

2012-01-01

To discuss the nature of and considerations in the study of social processes. Social processes include the elements of time, change and human interaction and many phenomena of interest to nurse researchers. Despite the significance of social processes for nursing practice and the labelling in many studies of phenomena as processes, there seems to be an inability to describe processes fully. The paper includes a presentation of two methodological approaches for illuminating the dynamics of social processes: participant observation and prospective time-series designs. Strengths and limitations of the two paradigmatically different approaches are offered. The method an investigator chooses should be considered selectively and appropriately according to the nature of the problem, what is known about the phenomena to be studied, and the investigator's world view and theoretical perspective. The conceptualisation of process can also influence the methodological choice. Capturing a social process in its entirety with either a qualitative or quantitative approach can be a difficult task. The focus of this paper is an initiation and expansion of the dialogue about which methods provide the best insight into social processes. This knowledge may offer opportunities for nurse researchers to design and implement interventions for individuals as they progress through life events.

Franz Kafka in the Design Studio: A Hermeneutic-Phenomenological Approach to Architectural Design Education

ERIC Educational Resources Information Center

Hisarligil, Beyhan Bolak

2012-01-01

This article demonstrates the outcomes of taking a hermeneutic phenomenological approach to architectural design and discusses the potentials for imaginative reasoning in design education. This study tests the use of literature as a verbal form of art and design and the contribution it can make to imaginative design processes--which are all too…

Comparison of Designer's Design Thinking Modes in Digital and Traditional Sketches

ERIC Educational Resources Information Center

Wu, Jun-Chieh; Chen, Cheng-Chi; Chen, Hsin-Chia

2012-01-01

The internal design thinking behaviour of designers in the concept development has been an important issue of cognitive psychology. In this study, the design thinking process designers have in applying digital media and traditional paper in the early concept development stage was explored. Special focus was made on the structure and procedure of…

May Stakeholders be Involved in Design Without Informed Consent? The Case of Hidden Design.

PubMed

Pols, A J K

2017-06-01

Stakeholder involvement in design is desirable from both a practical and an ethical point of view. It is difficult to do well, however, and some problems recur again and again, both of a practical nature, e.g. stakeholders acting strategically rather than openly, and of an ethical nature, e.g. power imbalances unduly affecting the outcome of the process. Hidden Design has been proposed as a method to deal with the practical problems of stakeholder involvement. It aims to do so by taking the observation of stakeholder actions, rather than the outcomes of a deliberative process, as its input. Furthermore, it hides from stakeholders the fact that a design process is taking place so that they will not behave differently than they otherwise would. Both aspects of Hidden Design have raised ethical worries. In this paper I make an ethical analysis of what it means for a design process to leave participants uninformed or deceived rather than acquiring their informed consent beforehand, and to use observation of actions rather than deliberation as input for design, using Hidden Design as a case study. This analysis is based on two sets of normative guidelines: the ethical guidelines for psychological research involving deception or uninformed participants from two professional psychological organisations, and Habermasian norms for a fair and just (deliberative) process. It supports the conclusion that stakeholder involvement in design organised in this way can be ethically acceptable, though under a number of conditions and constraints.

Evolutionary and biological metaphors for engineering design

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jakiela, M.

1994-12-31

Since computing became generally available, there has been strong interest in using computers to assist and automate engineering design processes. Specifically, for design optimization and automation, nonlinear programming and artificial intelligence techniques have been extensively studied. New computational techniques, based upon the natural processes of evolution, adaptation, and learing, are showing promise because of their generality and robustness. This presentation will describe the use of two such techniques, genetic algorithms and classifier systems, for a variety of engineering design problems. Structural topology optimization, meshing, and general engineering optimization are shown as example applications.

Development of system design information for carbon dioxide using an amine type sorber

NASA Technical Reports Server (NTRS)

Rankin, R. L.; Roehlich, F.; Vancheri, F.

1971-01-01

Development work on system design information for amine type carbon dioxide sorber is reported. Amberlite IR-45, an aminated styrene divinyl benzene matrix, was investigated to determine the influence of design parameters of sorber particle size, process flow rate, CO2 partial pressure, total pressure, and bed designs. CO2 capacity and energy requirements for a 4-man size system were related mathematically to important operational parameters. Some fundamental studies in CO2 sorber capacity, energy requirements, and process operation were also performed.

Creativity in ergonomic design: a supplemental value-adding source for product and service development.

PubMed

Zeng, Liang; Proctor, Robert W; Salvendy, Gavriel

2010-08-01

This article investigates the role of creativity in ergonomic design and the generic process of developing creative products and services. Creativity is gaining increased emphasis in both academia and industry. More than 50 years of research in creativity indicates that creativity is key to product and service innovation. Nevertheless, there is scarcely any comprehensive review dedicated to appraising the complex construct of creativity, the underlying cognitive process, and the role of creativity in product and service development. We review relevant literature regarding creativity, creative cognition, and the engineering design process to appraise the role of creativity in ergonomic design and to construct a conceptual model of creative product and service development. A framework of ergodesign creativity is advanced that highlights the central role of creativity in synergistically addressing the four dimensions of ergonomic design: functionality, safety, usability, and affectivity. A conceptual model of creative design process is then constructed that is goal oriented and is initiated by active problem finding and problem formulating. This process is carried out in a recursive and dynamic way, facilitated by creative thinking strategies. It is proposed that ergodesign creativity can add supplemental value to products and services, which subsequently affects consumer behavior and helps organizations gain competitive advantage. The proposed conceptual framework of ergodesign creativity and creative design process can serve as the ground for future theory development. Propositions advanced in this study should facilitate designers generating products and services that are creative and commercially competitive.

Integrated command, control, communication and computation system design study. Summary of tasks performed

NASA Technical Reports Server (NTRS)

1982-01-01

A summary of tasks performed on an integrated command, control, communication, and computation system design study is given. The Tracking and Data Relay Satellite System command and control system study, an automated real-time operations study, and image processing work are discussed.

Reconciling research and community priorities in participatory trials: application to Padres Informados/Jovenes Preparados.

PubMed

Allen, Michele L; Garcia-Huidobro, Diego; Bastian, Tiana; Hurtado, G Ali; Linares, Roxana; Svetaz, María Veronica

2017-06-01

Participatory research (PR) trials aim to achieve the dual, and at times competing, demands of producing an intervention and research process that address community perspectives and priorities, while establishing intervention effectiveness. To identify research and community priorities that must be reconciled in the areas of collaborative processes, study design and aim and study implementation quality in order to successfully conduct a participatory trial. We describe how this reconciliation was approached in the smoking prevention participatory trial Padres Informados/Jovenes Preparados (Informed Parents/Prepared Youth) and evaluate the success of our reconciled priorities. Data sources to evaluate success of the reconciliations included a survey of all partners regarding collaborative group processes, intervention participant recruitment and attendance and surveys of enrolled study participants assessing intervention outcomes. While we successfully achieved our reconciled collaborative processes and implementation quality goals, we did not achieve our reconciled goals in study aim and design. Due in part to the randomized wait-list control group design chosen in the reconciliation process, we were not able to demonstrate overall efficacy of the intervention or offer timely services to families in need of support. Achieving the goals of participatory trials is challenging but may yield community and research benefits. Innovative research designs are needed to better support the complex goals of participatory trials. © The Author 2017. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Effect of mold designs on molten metal behaviour in high-pressure die casting

NASA Astrophysics Data System (ADS)

Ibrahim, M. D.; Rahman, M. R. A.; Khan, A. A.; Mohamad, M. R.; Suffian, M. S. Z. M.; Yunos, Y. S.; Wong, L. K.; Mohtar, M. Z.

2017-04-01

This paper presents a research study conducted in a local automotive component manufacturer that produces aluminium alloy steering housing local and global markets. This study is to investigate the effect of design modification of mold in die casting as to improve the production rate. Design modification is carried out on the casting shot of the mold. Computer flow simulation was carried out to study the flow of molten metal in the mold with respect to the mold design modification. The design parameters of injection speed, die temperature and clamping force has been included in the study. The result of the simulation showed that modifications of casting shot give significant impact towards the molten flow behaviour in casting process. The capabilities and limitations of die casting process simulation to conduct defect analysis had been optimized. This research will enhance the efficiency of the mass production of the industry of die casting with the understanding of defect analysis, which lies on the modification of the mold design, a way early in its stages of production.

Methodology on Investigating the Influences of Automated Material Handling System in Automotive Assembly Process

NASA Astrophysics Data System (ADS)

Saffar, Seha; Azni Jafar, Fairul; Jamaludin, Zamberi

2016-02-01

A case study was selected as a method to collect data in actual industry situation. The study aimed to assess the influences of automated material handling system in automotive industry by proposing a new design of integration system through simulation, and analyze the significant effect and influence of the system. The method approach tool will be CAD Software (Delmia & Quest). The process of preliminary data gathering in phase 1 will collect all data related from actual industry situation. It is expected to produce a guideline and limitation in designing a new integration system later. In phase 2, an idea or concept of design will be done by using 10 principles of design consideration for manufacturing. A full factorial design will be used as design of experiment in order to analyze the performance measured of the integration system with the current system in case study. From the result of the experiment, an ANOVA analysis will be done to study the performance measured. Thus, it is expected that influences can be seen from the improvement made in the system.

The Effect of Design Modifications to the Typographical Layout of the New York State Elementary Science Learning Standards on User Preference and Process Time

ERIC Educational Resources Information Center

Arnold, Jeffery E.

2010-01-01

The purpose of this study was to determine the effect of four different design layouts of the New York State elementary science learning standards on user processing time and preference. Three newly developed layouts contained the same information as the standards core curriculum. In this study, the layout of the core guide is referred to as Book.…

The Impact of Inquiry Based Instruction on Science Process Skills and Self-Efficacy Perceptions of Pre-Service Science Teachers at a University Level Biology Laboratory

ERIC Educational Resources Information Center

Sen, Ceylan; Sezen Vekli, Gülsah

2016-01-01

The aim of this study is to determine the influence of inquiry-based teaching approach on pre-service science teachers' laboratory self-efficacy perceptions and scientific process skills. The quasi experimental model with pre-test-post-test control group design was used as an experimental design in this research. The sample of this study included…

GUIDE TO CONDUCTING TREATABILITY STUDIES UNDER CERCLA: SOIL WASHING - INTERIM GUIDANCE

EPA Science Inventory

Systematically conducted, well-documented treatability studies are an important component of the remedial investigation/feasibility study (RI/FS) process and the remedial design/remedial action (RD/RA) process under the Comprehensive Environmental Response, Compensation, and Liab...

GUIDE FOR CONDUCTING TREATABILITY STUDIES UNDER CERCLA: AEROBIC BIODEGRADATION REMEDY SCREENING

EPA Science Inventory

Systematically conducted, well-documented treatability studies are an important component of the remedial investigation/feasibility study (KU FS) process and the remedial design/remedial action (RD/RA) process under the Comprehensive Environmental Response, Compensation, and L...

GUIDE FOR CONDUCTING TREATABILITY STUDIES UNDER CERCLA: SOLVENT EXTRACTION - INTERIM GUIDANCE

EPA Science Inventory

Systematically conducted, well-documented treatability studies are an important component of the remedial investigation/feasibility study (RI/FS) process and the remedial design/remedial action (RD/RA) process under the Comprehensive Environmental Response, Compensation and Liabi...

GUIDE FOR CONDUCTING TREATABILITY STUDIES UNDER CERCLA: THERMAL DESORPTION - INTERIM GUIDANCE

EPA Science Inventory

Systematically conducted, well-documented treatability studies are an important component of the remedial investigation/feasibility study (RI/FS) process and the remedial design remedial action (RD/RA) process under the Comprehensive Environmental Response, Compensation, and Liab...

Importance of joint efforts for balanced process of designing and education

NASA Astrophysics Data System (ADS)

Mayorova, V. I.; Bannova, O. K.; Kristiansen, T.-H.; Igritsky, V. A.

2015-06-01

This paper discusses importance of a strategic planning and design process when developing long-term space exploration missions both robotic and manned. The discussion begins with reviewing current and/or traditional international perspectives on space development at the American, Russian and European space agencies. Some analogies and comparisons will be drawn upon analysis of several international student collaborative programs: Summer International workshops at the Bauman Moscow State Technical University, International European Summer Space School "Future Space Technologies and Experiments in Space", Summer school at Stuttgart University in Germany. The paper will focus on discussion about optimization of design and planning processes for successful space exploration missions and will highlight importance of the following: understanding connectivity between different levels of human being and machinery; simultaneous mission planning approach; reflections and correlations between disciplines involved in planning and executing space exploration missions; knowledge gained from different disciplines and through cross-applying and re-applying design approaches between variable space related fields of study and research. The conclusions will summarize benefits and complications of applying balanced design approach at all levels of the design process. Analysis of successes and failures of organizational efforts in space endeavors is used as a methodological approach to identify key questions to be researched as they often cause many planning and design processing problems.

Designing Pulse Laser Surface Modification of H13 Steel Using Response Surface Method

NASA Astrophysics Data System (ADS)

Aqida, S. N.; Brabazon, D.; Naher, S.

2011-01-01

This paper presents a design of experiment (DOE) for laser surface modification process of AISI H13 tool steel in achieving the maximum hardness and minimum surface roughness at a range of modified layer depth. A Rofin DC-015 diffusion-cooled CO2 slab laser was used to process AISI H13 tool steel samples. Samples of 10 mm diameter were sectioned to 100 mm length in order to process a predefined circumferential area. The parameters selected for examination were laser peak power, overlap percentage and pulse repetition frequency (PRF). The response surface method with Box-Behnken design approach in Design Expert 7 software was used to design the H13 laser surface modification process. Metallographic study and image analysis were done to measure the modified layer depth. The modified surface roughness was measured using two-dimensional surface profilometer. The correlation of the three laser processing parameters and the modified surface properties was specified by plotting three-dimensional graph. The hardness properties were tested at 981 mN force. From metallographic study, the laser modified surface depth was between 37 μm and 150 μm. The average surface roughness recorded from the 2D profilometry was at a minimum value of 1.8 μm. The maximum hardness achieved was between 728 and 905 HV0.1. These findings are significant to modern development of hard coatings for wear resistant applications.

DESIGN INFORMATION ON FINE PORE AERATION SYSTEMS

EPA Science Inventory

Field studies were conducted over several years at municipal wastewater treatment plants employing line pore diffused aeration systems. These studies were designed to produce reliable information on the performance and operational requirements of fine pore devices under process ...

SLS Trade Study 0058: Day of Launch (DOL) Wind Biasing

NASA Technical Reports Server (NTRS)

Decker, Ryan K.; Duffin, Paul; Hill, Ashley; Beck, Roger; Dukeman, Greg

2014-01-01

SLS heritage hardware and legacy designs have shown load exceedances at several locations during Design Analysis Cycles (DAC): MPCV Z bending moments; ICPS Electro-Mechanical Actuator (EMA) loads; Core Stage loads just downstream of Booster forward interface. SLS Buffet Loads Mitigation Task Team (BLMTT) tasked to study issue. Identified low frequency buffet load responses are a function of the vehicle's total angle of attack (AlphaTotal). SLS DOL Wind Biasing Trade team to analyze DOL wind biasing methods to limit maximum AlphaTotal in the M0.8 - 2.0 altitude region for EM-1 and EM-2 missions through investigating: Trajectory design process; Wind wavelength filtering options; Launch availability; DOL process to achieve shorter processing/uplink timeline. Trade Team consisted of personnel supporting SLS, MPCV, GSDO programs.

Collaborative Design Practices in Technology Mediated Learning

ERIC Educational Resources Information Center

Seitamaa-Hakkarainen, Pirita; Kangas, Kaiju; Raunio, Anna-Mari; Hakkarainen, Kai

2012-01-01

The present article examines how practices of computer-supported collaborative designing may be implemented in an elementary classroom. We present a case study in which 12-year-old students engaged in architectural design under the guidance of their teacher and a professional designer. The students were engaged in all aspects of design processes,…

A Concept Transformation Learning Model for Architectural Design Learning Process

ERIC Educational Resources Information Center

Wu, Yun-Wu; Weng, Kuo-Hua; Young, Li-Ming

2016-01-01

Generally, in the foundation course of architectural design, much emphasis is placed on teaching of the basic design skills without focusing on teaching students to apply the basic design concepts in their architectural designs or promoting students' own creativity. Therefore, this study aims to propose a concept transformation learning model to…

Design of a Fission 99 Mo Recovery Process and Implications toward Mo Adsorption Mechanism on Titania and Alumina Sorbents

DOE Office of Scientific and Technical Information (OSTI.GOV)

Stepinski, Dominique C.; Youker, Amanda J.; Krahn, Elizabeth O.

2017-03-01

Molybdenum-99 is a parent of the most widely used medical isotope technetium-99m. Proliferation concerns have prompted development of alternative Mo production methods utilizing low enriched uranium. Alumina and titania sorbents were evaluated for separation of Mo from concentrated uranyl nitrate solutions. System, mass transfer, and isotherm parameters were determined to enable design of Mo separation processes under a wide range of conditions. A model-based approach was utilized to design representative commercial-scale column processes. The designs and parameters were verified with bench-scale experiments. The results are essential for design of Mo separation processes from irradiated uranium solutions, selection of support materialmore » and process optimization. Mo uptake studies show that adsorption decreases with increasing concentration of uranyl nitrate; howeveL, examination of Mo adsorption as a function of nitrate ion concentration shows no dependency, indicating that uranium competes with Mo for adsorption sites. These results are consistent with reports indicating that Mo forms inner-sphere complexes with titania and alumina surface groups.« less

Process Feasibility Study in Support of Silicon Material, Task 1

NASA Technical Reports Server (NTRS)

Li, K. Y.; Hansen, K. C.; Yaws, C. L.

1979-01-01

During this reporting period, major activies were devoted to process system properties, chemical engineering and economic analyses. Analyses of process system properties was continued for materials involved in the alternate processes under consideration for solar cell grade silicon. The following property data are reported for silicon tetrafluoride: critical constants, vapor pressure, heat of varporization, heat capacity, density, surface tension, viscosity, thermal conductivity, heat of formation and Gibb's free energy of formation. Chemical engineering analysis of the BCL process was continued with primary efforts being devoted to the preliminary process design. Status and progress are reported for base case conditions; process flow diagram; reaction chemistry; material and energy balances; and major process equipment design.

An ergonomics action research demonstration: integrating human factors into assembly design processes.

PubMed

Village, J; Greig, M; Salustri, F; Zolfaghari, S; Neumann, W P

2014-01-01

In action research (AR), the researcher participates 'in' the actions in an organisation, while simultaneously reflecting 'on' the actions to promote learning for both the organisation and the researchers. This paper demonstrates a longitudinal AR collaboration with an electronics manufacturing firm where the goal was to improve the organisation's ability to integrate human factors (HF) proactively into their design processes. During the three-year collaboration, all meetings, workshops, interviews and reflections were digitally recorded and qualitatively analysed to inform new 'actions'. By the end of the collaboration, HF tools with targets and sign-off by the HF specialist were integrated into several stages of the design process, and engineers were held accountable for meeting the HF targets. We conclude that the AR approach combined with targeting multiple initiatives at different stages of the design process helped the organisation find ways to integrate HF into their processes in a sustainable way. Researchers acted as a catalyst to help integrate HF into the engineering design process in a sustainable way. This paper demonstrates how an AR approach can help achieve HF integration, the benefits of using a reflective stance and one method for reporting an AR study.

Making Mentoring Stick: A Case Study

ERIC Educational Resources Information Center

Karallis, Takis; Sandelands, Eric

2009-01-01

Purpose: This paper seeks to provide a case study of the mentoring process within Kentz Engineers & Constructors. Design/methodology/approach: The paper reflects the experiences of those leading the mentoring process within Kentz with insights extracted from a process of action, reflection and live experimentation. Findings: The paper…

Integrating Lean Exploration Loops Into Healthcare Facility Design.

PubMed

Mazur, Lukasz M; Johnson, Kendra; Pooya, Pegah; Chadwick, Janet; McCreery, John

2017-04-01

To explore what, when, and how Lean methods and tools can add value during the programming phase of design through providing additional resources and support to project leadership and the architectural design team. This case study-based research took place at one large academic hospital during design efforts of a surgical tower to house 19 operating rooms (ORs) and support spaces including pre- and postop, central processing and distribution, and materials management. Surgical services project leadership asked for support from Lean practitioners during the design process. Lean exploration loops (LELs) were conducted to generate evidence to support stakeholders, as they made important decisions about the new building design. The analyses conducted during LELs were primarily focused on the relative advantages of a large footprint with few floors or a smaller footprint with more floors and support spaces not collocated adjacent to ORs on the same floor. LELs resulted in quantifications of key operational and design features (e.g., design preferences of employees and patients, horizontal distance travel, and elevator utilization studies), which in turn complemented the architectural design process and created an opportunities to gain buy-in and consensus from stakeholders through their active participation in many of the analyses. We found Lean tools and methods to be of most value during programming phase when focused on the high-level operational and design issues to help establish buy-in and consensus among stakeholders, while acknowledging that there is often not enough design detail to perform accurate analysis.

Is the linear modeling technique good enough for optimal form design? A comparison of quantitative analysis models.

PubMed

Lin, Yang-Cheng; Yeh, Chung-Hsing; Wang, Chen-Cheng; Wei, Chun-Chun

2012-01-01

How to design highly reputable and hot-selling products is an essential issue in product design. Whether consumers choose a product depends largely on their perception of the product image. A consumer-oriented design approach presented in this paper helps product designers incorporate consumers' perceptions of product forms in the design process. The consumer-oriented design approach uses quantification theory type I, grey prediction (the linear modeling technique), and neural networks (the nonlinear modeling technique) to determine the optimal form combination of product design for matching a given product image. An experimental study based on the concept of Kansei Engineering is conducted to collect numerical data for examining the relationship between consumers' perception of product image and product form elements of personal digital assistants (PDAs). The result of performance comparison shows that the QTTI model is good enough to help product designers determine the optimal form combination of product design. Although the PDA form design is used as a case study, the approach is applicable to other consumer products with various design elements and product images. The approach provides an effective mechanism for facilitating the consumer-oriented product design process.

Is the Linear Modeling Technique Good Enough for Optimal Form Design? A Comparison of Quantitative Analysis Models

PubMed Central

Lin, Yang-Cheng; Yeh, Chung-Hsing; Wang, Chen-Cheng; Wei, Chun-Chun

2012-01-01

How to design highly reputable and hot-selling products is an essential issue in product design. Whether consumers choose a product depends largely on their perception of the product image. A consumer-oriented design approach presented in this paper helps product designers incorporate consumers' perceptions of product forms in the design process. The consumer-oriented design approach uses quantification theory type I, grey prediction (the linear modeling technique), and neural networks (the nonlinear modeling technique) to determine the optimal form combination of product design for matching a given product image. An experimental study based on the concept of Kansei Engineering is conducted to collect numerical data for examining the relationship between consumers' perception of product image and product form elements of personal digital assistants (PDAs). The result of performance comparison shows that the QTTI model is good enough to help product designers determine the optimal form combination of product design. Although the PDA form design is used as a case study, the approach is applicable to other consumer products with various design elements and product images. The approach provides an effective mechanism for facilitating the consumer-oriented product design process. PMID:23258961

UOE Pipe Manufacturing Process Simulation: Equipment Designing and Construction

NASA Astrophysics Data System (ADS)

Delistoian, Dmitri; Chirchor, Mihael

2017-12-01

UOE pipe manufacturing process influence directly on pipeline resilience and operation capacity. At present most spreaded pipe manufacturing method is UOE. This method is based on cold forming. After each technological step appears a certain stress and strain level. For pipe stress strain study is designed and constructed special equipment that simulate entire technological process.UOE pipe equipment is dedicated for manufacturing of longitudinally submerged arc welded DN 400 (16 inch) steel pipe.

Influence of Different Container Closure Systems and Capping Process Parameters on Product Quality and Container Closure Integrity (CCI) in GMP Drug Product Manufacturing.

PubMed

Mathaes, Roman; Mahler, Hanns-Christian; Roggo, Yves; Huwyler, Joerg; Eder, Juergen; Fritsch, Kamila; Posset, Tobias; Mohl, Silke; Streubel, Alexander

2016-01-01

Capping equipment used in good manufacturing practice manufacturing features different designs and a variety of adjustable process parameters. The overall capping result is a complex interplay of the different capping process parameters and is insufficiently described in literature. It remains poorly studied how the different capping equipment designs and capping equipment process parameters (e.g., pre-compression force, capping plate height, turntable rotating speed) contribute to the final residual seal force of a sealed container closure system and its relation to container closure integrity and other drug product quality parameters. Stopper compression measured by computer tomography correlated to residual seal force measurements.In our studies, we used different container closure system configurations from different good manufacturing practice drug product fill & finish facilities to investigate the influence of differences in primary packaging, that is, vial size and rubber stopper design on the capping process and the capped drug product. In addition, we compared two large-scale good manufacturing practice manufacturing capping equipment and different capping equipment settings and their impact on product quality and integrity, as determined by residual seal force.The capping plate to plunger distance had a major influence on the obtained residual seal force values of a sealed vial, whereas the capping pre-compression force and the turntable rotation speed showed only a minor influence on the residual seal force of a sealed vial. Capping process parameters could not easily be transferred from capping equipment of different manufacturers. However, the residual seal force tester did provide a valuable tool to compare capping performance of different capping equipment. No vial showed any leakage greater than 10(-8)mbar L/s as measured by a helium mass spectrometry system, suggesting that container closure integrity was warranted in the residual seal force range tested for the tested container closure systems. Capping equipment used in good manufacturing practice manufacturing features different designs and a variety of adjustable process parameters. The overall capping result is a complex interplay of the different capping process parameters and is insufficiently described in the literature. It remains poorly studied how the different capping equipment designs and capping equipment process parameters contribute to the final capping result.In this study, we used different container closure system configurations from different good manufacturing process drug product fill & finish facilities to investigate the influence of the vial size and the rubber stopper design on the capping process. In addition, we compared two examples of large-scale good manufacturing process capping equipment and different capping equipment settings and their impact on product quality and integrity, as determined by residual seal force. © PDA, Inc. 2016.

Process parameters in the manufacture of ceramic ZnO nanofibers made by electrospinning

NASA Astrophysics Data System (ADS)

Nonato, Renato C.; Morales, Ana R.; Rocha, Mateus C.; Nista, Silvia V. G.; Mei, Lucia H. I.; Bonse, Baltus C.

2017-01-01

Zinc oxide (ZnO) nanofibers were prepared by electrospinning under different conditions using a solution of poly(vinyl alcohol) and zinc acetate as precursor. A 23 factorial design was made to study the influence of the process parameters in the electrospinning (collector distance, flow rate and voltage), and a 22 factorial design was made to study the influence of the calcination process (time and temperature). SEM images were made to analyze the fiber morphology before and after calcination process, and the images were made to measure the nanofiber diameter. X-ray diffraction was made to analyze the total precursor conversion to ZnO and the elimination of the polymeric carrier.

Water recovery and solid waste processing for aerospace and domestic applications. Volume 1: Final report

NASA Technical Reports Server (NTRS)

Murray, R. W.

1973-01-01

A comprehensive study of advanced water recovery and solid waste processing techniques employed in both aerospace and domestic or commercial applications is reported. A systems approach was used to synthesize a prototype system design of an advanced water treatment/waste processing system. Household water use characteristics were studied and modified through the use of low water use devices and a limited amount of water reuse. This modified household system was then used as a baseline system for development of several water treatment waste processing systems employing advanced techniques. A hybrid of these systems was next developed and a preliminary design was generated to define system and hardware functions.

Icon and user interface design for emergency medical information systems: a case study.

PubMed

Salman, Y Batu; Cheng, Hong-In; Patterson, Patrick E

2012-01-01

A usable medical information system should allow for reliable and accurate interaction between users and the system in emergencies. A participatory design approach was used to develop a medical information system in two Turkish hospitals. The process consisted of task and user analysis, an icon design survey, initial icon design, final icon design and evaluation, and installation of the iconic medical information system with the icons. We observed work sites to note working processes and tasks related to the information system and interviewed medical personnel. Emergency personnel then participated in the design process to develop a usable graphical user interface, by drawing icon sketches for 23 selected tasks. Similar sketches were requested for specific tasks such as family medical history, contact information, translation, addiction, required inspections, requests and applications, and nurse observations. The sketches were analyzed and redesigned into computer icons by professional designers and the research team. A second group of physicians and nurses then tested the understandability of the icons. The user interface layout was examined and evaluated by system users, followed by the system's installation. Medical personnel reported the participatory design process was interesting and believed the resulting designs would be more familiar and friendlier. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

Systematic procedure for designing processes with multiple environmental objectives.

PubMed

Kim, Ki-Joo; Smith, Raymond L

2005-04-01

Evaluation of multiple objectives is very important in designing environmentally benign processes. It requires a systematic procedure for solving multiobjective decision-making problems due to the complex nature of the problems, the need for complex assessments, and the complicated analysis of multidimensional results. In this paper, a novel systematic procedure is presented for designing processes with multiple environmental objectives. This procedure has four steps: initialization, screening, evaluation, and visualization. The first two steps are used for systematic problem formulation based on mass and energy estimation and order of magnitude analysis. In the third step, an efficient parallel multiobjective steady-state genetic algorithm is applied to design environmentally benign and economically viable processes and to provide more accurate and uniform Pareto optimal solutions. In the last step a new visualization technique for illustrating multiple objectives and their design parameters on the same diagram is developed. Through these integrated steps the decision-maker can easily determine design alternatives with respect to his or her preferences. Most importantly, this technique is independent of the number of objectives and design parameters. As a case study, acetic acid recovery from aqueous waste mixtures is investigated by minimizing eight potential environmental impacts and maximizing total profit. After applying the systematic procedure, the most preferred design alternatives and their design parameters are easily identified.

Didactital design of mathematics teaching in primary school

NASA Astrophysics Data System (ADS)

Nur’aeni, E.; Muharram, M. R. W.

2018-05-01

The fact that the low ability of geometrical understanding of primary school students is what triggers this study to be conducted. Thus, this research aimed to find out how to create a didactical design of students' mathematical understanding, particularly on one of geometry materials that is unit of length. A qualitative approach promoting Didactical Design Research (DDR) was administered in this study. Participants of the study were primary school students in Tasikmalaya, an city in West Java Province, Indonesia. The results show that there was a learning design based on learning obstacles found in the mathematics teaching and learning processes. The learning obstacles comprised students' difficulties in memorizing, relating, and operating the standards of unit of lengths. It has been proven that the most influential factor in the success of mathematics teaching and learning processes is the use of creative media.

Study of percolation behavior depending on molecular structure design

NASA Astrophysics Data System (ADS)

Yu, Ji Woong; Lee, Won Bo

Each differently designed anisotropic nano-crystals(ANCs) are studied using Langevin dynamic simulation and their percolation behaviors are presented. Popular molecular dynamics software LAMMPS was used to design the system and perform the simulation. We calculated the minimum number density at which percolation occurs(i.e. percolation threshold), radial distribution function, and the average number of ANCs for a cluster. Electrical conductivity is improved when the number of transfers of electrons between ANCs, so called ''inter-hopping process'', which has the considerable contribution to resistance decreases and the number of inter-hopping process is directly related with the concentration of ANCs. Therefore, with the investigation of relationship between molecular architecture and percolation behavior, optimal design of ANC can be achieved.

Computer Design Technology of the Small Thrust Rocket Engines Using CAE / CAD Systems

NASA Astrophysics Data System (ADS)

Ryzhkov, V.; Lapshin, E.

2018-01-01

The paper presents an algorithm for designing liquid small thrust rocket engine, the process of which consists of five aggregated stages with feedback. Three stages of the algorithm provide engineering support for design, and two stages - the actual engine design. A distinctive feature of the proposed approach is a deep study of the main technical solutions at the stage of engineering analysis and interaction with the created knowledge (data) base, which accelerates the process and provides enhanced design quality. The using multifunctional graphic package Siemens NX allows to obtain the final product -rocket engine and a set of design documentation in a fairly short time; the engine design does not require a long experimental development.

What is a good public participation process? Five perspectives from the public.

PubMed

Webler, T; Tuler, S; Krueger, R

2001-03-01

It is now widely accepted that members of the public should be involved in environmental decision-making. This has inspired many to search for principles that characterize good public participation processes. In this paper we report on a study that identifies discourses about what defines a good process. Our case study was a forest planning process in northern New England and New York. We employed Q methodology to learn how participants characterize a good process differently, by selecting, defining, and privileging different principles. Five discourses, or perspectives, about good process emerged from our study. One perspective emphasizes that a good process acquires and maintains popular legitimacy. A second sees a good process as one that facilitates an ideological discussion. A third focuses on the fairness of the process. A fourth perspective conceptualizes participatory processes as a power struggle--in this instance a power play between local land-owning interests and outsiders. A fifth perspective highlights the need for leadership and compromise. Dramatic differences among these views suggest an important challenge for those responsible for designing and carrying out public participation processes. Conflicts may emerge about process designs because people disagree about what is good in specific contexts.

Study for the optimization of a transport aircraft wing for maximum fuel efficiency. Volume 1: Methodology, criteria, aeroelastic model definition and results

NASA Technical Reports Server (NTRS)

Radovcich, N. A.; Dreim, D.; Okeefe, D. A.; Linner, L.; Pathak, S. K.; Reaser, J. S.; Richardson, D.; Sweers, J.; Conner, F.

1985-01-01

Work performed in the design of a transport aircraft wing for maximum fuel efficiency is documented with emphasis on design criteria, design methodology, and three design configurations. The design database includes complete finite element model description, sizing data, geometry data, loads data, and inertial data. A design process which satisfies the economics and practical aspects of a real design is illustrated. The cooperative study relationship between the contractor and NASA during the course of the contract is also discussed.

Evaluating the Healthy Start program. Design development to evaluative assessment.

PubMed

Raykovich, K S; McCormick, M C; Howell, E M; Devaney, B L

1996-09-01

The national evaluation of the federally funded Healthy Start program involved translating a design for a process and outcomes evaluation and standard maternal and infant data set, both developed prior to the national evaluation contract award, into an evaluation design and client data collection protocol that could be used to evaluate 15 diverse grantees. This article discusses the experience of creating a process and outcomes evaluation design that was both substantively and methodologically appropriate given such issues as the diversity of grantees and their community-based intervention strategies; the process of accessing secondary data sources, including vital records; the quality of client level data submissions; and the need to incorporate both qualitative and quantitative approaches into the evaluation design. The relevance of this experience for the conduct of other field studies of public health interventions is discussed.

Data on conceptual design of cryogenic energy storage system combined with liquefied natural gas regasification process.

PubMed

Lee, Inkyu; Park, Jinwoo; Moon, Il

2017-12-01

This paper describes data of an integrated process, cryogenic energy storage system combined with liquefied natural gas (LNG) regasification process. The data in this paper is associated with the article entitled "Conceptual Design and Exergy Analysis of Combined Cryogenic Energy Storage and LNG Regasification Processes: Cold and Power Integration" (Lee et al., 2017) [1]. The data includes the sensitivity case study dataset of the air flow rate and the heat exchanging feasibility data by composite curves. The data is expected to be helpful to the cryogenic energy process development.

Analysis of flow field characteristics in IC equipment chamber based on orthogonal design

NASA Astrophysics Data System (ADS)

Liu, W. F.; Yang, Y. Y.; Wang, C. N.

2017-01-01

This paper aims to study the influence of the configuration of processing chamber as a part of IC equipment on flow field characteristics. Four parameters, including chamber height, chamber diameter, inlet mass flow rate and outlet area, are arranged using orthogonally design method to study their influence on flow distribution in the processing chamber with the commercial software-Fluent. The velocity, pressure and temperature distribution above the holder were analysed respectively. The velocity difference value of the gas flow above the holder is defined as the evaluation criteria to evaluate the uniformity of the gas flow. The quantitative relationship between key parameters and the uniformity of gas flow was found through analysis of experimental results. According to our study, the chamber height is the most significant factor, and then follows the outlet area, chamber diameter and inlet mass flow rate. This research can provide insights into the study and design of configuration of etcher, plasma enhanced chemical vapor deposition (PECVD) equipment, and other systems with similar configuration and processing condition.

Combining principles of Cognitive Load Theory and diagnostic error analysis for designing job aids: Effects on motivation and diagnostic performance in a process control task.

PubMed

Kluge, Annette; Grauel, Britta; Burkolter, Dina

2013-03-01

Two studies are presented in which the design of a procedural aid and the impact of an additional decision aid for process control were assessed. In Study 1, a procedural aid was developed that avoids imposing unnecessary extraneous cognitive load on novices when controlling a complex technical system. This newly designed procedural aid positively affected germane load, attention, satisfaction, motivation, knowledge acquisition and diagnostic speed for novel faults. In Study 2, the effect of a decision aid for use before the procedural aid was investigated, which was developed based on an analysis of diagnostic errors committed in Study 1. Results showed that novices were able to diagnose both novel faults and practised faults, and were even faster at diagnosing novel faults. This research contributes to the question of how to optimally support novices in dealing with technical faults in process control. Copyright © 2012 Elsevier Ltd and The Ergonomics Society. All rights reserved.

Shyness and Emotion-Processing Skills in Preschoolers: A 6-Month Longitudinal Study

ERIC Educational Resources Information Center

Strand, Paul S.; Cerna, Sandra; Downs, Andrew

2008-01-01

The present study utilized a short-term longitudinal research design to examine the hypothesis that shyness in preschoolers is differentially related to different aspects of emotion processing. Using teacher reports of shyness and performance measures of emotion processing, including (1) facial emotion recognition, (2) non-facial emotion…

Contributing Factors to a Successful Online Course Development Process

ERIC Educational Resources Information Center

Stevens, Karl B.

2013-01-01

This qualitative case study examined the experiences of instructional designers and professors during the online course development process. The purpose of this study was to determine if their experiences had an effect on the process itself. Data analysis revealed five emergent themes: communication, commitment to quality online courses,…

Modular space station, phase B extension. Information management advanced development. Volume 4: Data processing assembly

NASA Technical Reports Server (NTRS)

Gerber, C. R.

1972-01-01

The computation and logical functions which are performed by the data processing assembly of the modular space station are defined. The subjects discussed are: (1) requirements analysis, (2) baseline data processing assembly configuration, (3) information flow study, (4) throughput simulation, (5) redundancy study, (6) memory studies, and (7) design requirements specification.

Optimization of a Coupling Process for Insulin Degludec According to a Quality by Design (QbD) Paradigm.

PubMed

Nie, Lei; Hu, Mingming; Yan, Xu; Guo, Tingting; Wang, Haibin; Zhang, Sheng; Qu, Haibin

2018-05-03

This case study described a successful application of the quality by design (QbD) principles to a coupling process development of insulin degludec. Failure mode effects analysis (FMEA) risk analysis was first used to recognize critical process parameters (CPPs). Five CPPs, including coupling temperature (Temp), pH of desB30 solution (pH), reaction time (Time), desB30 concentration (Conc), and molar equivalent of ester per mole of desB30 insulin (MolE), were then investigated using a fractional factorial design. The curvature effect was found significant, indicating the requirement of second-order models. Afterwards, a central composite design was built with an augmented star and center points study. Regression models were developed for the CPPs to predict the purity and yield of predegludec using above experimental data. The R 2 and adjusted R 2 were higher than 96 and 93% for the two models respectively. The Q 2 values were more than 80% indicating a good predictive ability of models. MolE was found to be the most significant factor affecting both yield and purity of predegludec. Temp, pH, and Conc were also significant for predegludec purity, while Time appeared to remarkably influence the yield model. The multi-dimensional design space and normal operating region (NOR) with a robust setpoint were determined using a probability-based Monte-Carlo simulation method. The verified experimental results showed that the design space was reliable and effective. This study enriches the understanding of acetylation process and is instructional to other complicated operations in biopharmaceutical engineering.

Designing for Mathematical Abstraction

ERIC Educational Resources Information Center

Pratt, Dave; Noss, Richard

2010-01-01

Our focus is on the design of systems (pedagogical, technical, social) that encourage mathematical abstraction, a process we refer to as "designing for abstraction." In this paper, we draw on detailed design experiments from our research on children's understanding about chance and distribution to re-present this work as a case study in designing…

Development Research of a Teachers' Educational Performance Support System: The Practices of Design, Development, and Evaluation

ERIC Educational Resources Information Center

Hung, Wei-Chen; Smith, Thomas J.; Harris, Marian S.; Lockard, James

2010-01-01

This study adopted design and development research methodology (Richey & Klein, "Design and development research: Methods, strategies, and issues," 2007) to systematically investigate the process of applying instructional design principles, human-computer interaction, and software engineering to a performance support system (PSS) for behavior…

Demonstrating Empathy: A Phenomenological Study of Instructional Designers Making Instructional Strategy Decisions for Adult Learners

ERIC Educational Resources Information Center

Vann, Linda S.

2017-01-01

Instructional designers are tasked with making instructional strategy decisions to facilitate achievement of learning outcomes as part of their professional responsibilities. While the instructional design process includes learner analysis, that analysis alone does not embody opportunities to assist instructional designers with demonstrations of…

Implementation of quality by design toward processing of food products.

PubMed

Rathore, Anurag S; Kapoor, Gautam

2017-05-28

Quality by design (QbD) is a systematic approach that begins with predefined objectives and emphasizes product and process understanding and process control. It is an approach based on principles of sound science and quality risk management. As the food processing industry continues to embrace the idea of in-line, online, and/or at-line sensors and real-time characterization for process monitoring and control, the existing gaps with regard to our ability to monitor multiple parameters/variables associated with the manufacturing process will be alleviated over time. Investments made for development of tools and approaches that facilitate high-throughput analytical and process development, process analytical technology, design of experiments, risk analysis, knowledge management, and enhancement of process/product understanding would pave way for operational and economic benefits later in the commercialization process and across other product pipelines. This article aims to achieve two major objectives. First, to review the progress that has been made in the recent years on the topic of QbD implementation in processing of food products and second, present a case study that illustrates benefits of such QbD implementation.

Trajectory Dispersed Vehicle Process for Space Launch System

NASA Technical Reports Server (NTRS)

Statham, Tamara; Thompson, Seth

2017-01-01

The Space Launch System (SLS) vehicle is part of NASA's deep space exploration plans that includes manned missions to Mars. Manufacturing uncertainties in design parameters are key considerations throughout SLS development as they have significant effects on focus parameters such as lift-off-thrust-to-weight, vehicle payload, maximum dynamic pressure, and compression loads. This presentation discusses how the SLS program captures these uncertainties by utilizing a 3 degree of freedom (DOF) process called Trajectory Dispersed (TD) analysis. This analysis biases nominal trajectories to identify extremes in the design parameters for various potential SLS configurations and missions. This process utilizes a Design of Experiments (DOE) and response surface methodologies (RSM) to statistically sample uncertainties, and develop resulting vehicles using a Maximum Likelihood Estimate (MLE) process for targeting uncertainties bias. These vehicles represent various missions and configurations which are used as key inputs into a variety of analyses in the SLS design process, including 6 DOF dispersions, separation clearances, and engine out failure studies.

Intensification of the Students' Self-Development Process When Performing Design and Settlement Works on the "Machine Parts" Course

ERIC Educational Resources Information Center

Timerbaev, Rais Mingalievich; Muhutdinov, Rafis Habreevich; Danilov, Valeriy Fedorovich

2015-01-01

The article addresses issues related to the methodology of intensifying self-development process when performing design and settlement works on the "Machine Parts" course for the students studying in such areas of training as "Technology" and "Vocational Education" with the use of computer technologies. At the same…

Building Bridges to Connect the Disconnects: An Analysis of Business Program Design Processes

ERIC Educational Resources Information Center

Fleming, Debra L.

2008-01-01

The purpose of this study is to analyze current trends of design processes and redesign efforts for business programs. A review of the literature suggests business schools are not preparing graduates of their programs with the necessary knowledge, skills and dispositions as deemed appropriate to succeed in the world of work. Some research studies…

An Empirical Study of the Process of Crafting and Using Definitions

ERIC Educational Resources Information Center

Little, Angela Jean

2013-01-01

In this dissertation I analyze the process of crafting definitions whose purpose is classification. The context I examine is undergraduate upper-division physical science majors defining and naming sub-categories of a physical phenomenon in the context of a design task over an extended period of time. The goal of the design task is one of…

Personality, Resilience, Self-Regulation and Cognitive Ability Relevant to Teacher Selection

ERIC Educational Resources Information Center

Sautelle, Eleanor; Bowles, Terry; Hattie, John; Arifin, Daniel N.

2015-01-01

The current study uses social judgment theory to inform the design of processes to be used in selecting teachers for training programs. Developing a comprehensive selection process to identify individuals who are likely to succeed as teachers is a mechanism for improving teacher quality and raising the profile of the profession. The design of such…

Life Design Counseling Group Intervention with Portuguese Adolescents: A Process and Outcome Study

ERIC Educational Resources Information Center

Cardoso, Paulo; Janeiro, Isabel Nunes; Duarte, Maria Eduarda

2018-01-01

This article examines the process and outcome of a life design counseling group intervention with students in Grades 9 and 12. First, we applied a quasi-experimental methodology to analyze the intervention's effectiveness in promoting career certainty, career decision-making, self-efficacy, and career adaptability in a sample of 236 students.…

Using Sociocultural Perspectives: The Dynamic Process of Designing and Implementing Class Activities in an Online Japanese Language Course

ERIC Educational Resources Information Center

Shibakawa, Mayumi

2012-01-01

The study documented the dynamic process of designing and implementing instructional interventions in an online course of Japanese language and culture at a two-year college. The results have impact in three distinct areas: pedagogical, theoretical, and methodological. First, the interventions that encouraged student agency with rich…

Approach to design space from retrospective quality data.

PubMed

Puñal Peces, Daniel; García-Montoya, Encarna; Manich, Albert; Suñé-Negre, Josep Maria; Pérez-Lozano, Pilar; Miñarro, Montse; Ticó, Josep Ramon

2016-01-01

Nowadays, the entire manufacturing process is based on the current GMPs, which emphasize the reproducibility of the process, and companies have a lot of recorded data about their processes. The establishment of the design space (DS) from retrospective data for a wet compression process. A design of experiments (DoE) with historical data from 4 years of industrial production has been carried out using the experimental factors as the results of the previous risk analysis and eight key parameters (quality specifications) that encompassed process and quality control data. Software Statgraphics 5.0 was applied, and data were processed to obtain eight DS as well as their safe and working ranges. Experience shows that it is possible to determine DS retrospectively, being the greatest difficulty in handling and processing of high amounts of data; however, the practicality of this study is very interesting as it let have the DS with minimal investment in experiments since actual production batch data are processed statistically.

Microwave processing of a dental ceramic used in computer-aided design/computer-aided manufacturing.

PubMed

Pendola, Martin; Saha, Subrata

2015-01-01

Because of their favorable mechanical properties and natural esthetics, ceramics are widely used in restorative dentistry. The conventional ceramic sintering process required for their use is usually slow, however, and the equipment has an elevated energy consumption. Sintering processes that use microwaves have several advantages compared to regular sintering: shorter processing times, lower energy consumption, and the capacity for volumetric heating. The objective of this study was to test the mechanical properties of a dental ceramic used in computer-aided design/computer-aided manufacturing (CAD/CAM) after the specimens were processed with microwave hybrid sintering. Density, hardness, and bending strength were measured. When ceramic specimens were sintered with microwaves, the processing times were reduced and protocols were simplified. Hardness was improved almost 20% compared to regular sintering, and flexural strength measurements suggested that specimens were approximately 50% stronger than specimens sintered in a conventional system. Microwave hybrid sintering may preserve or improve the mechanical properties of dental ceramics designed for CAD/CAM processing systems, reducing processing and waiting times.

[Comparison of two algorithms for development of design space-overlapping method and probability-based method].

PubMed

Shao, Jing-Yuan; Qu, Hai-Bin; Gong, Xing-Chu

2018-05-01

In this work, two algorithms (overlapping method and the probability-based method) for design space calculation were compared by using the data collected from extraction process of Codonopsis Radix as an example. In the probability-based method, experimental error was simulated to calculate the probability of reaching the standard. The effects of several parameters on the calculated design space were studied, including simulation number, step length, and the acceptable probability threshold. For the extraction process of Codonopsis Radix, 10 000 times of simulation and 0.02 for the calculation step length can lead to a satisfactory design space. In general, the overlapping method is easy to understand, and can be realized by several kinds of commercial software without coding programs, but the reliability of the process evaluation indexes when operating in the design space is not indicated. Probability-based method is complex in calculation, but can provide the reliability to ensure that the process indexes can reach the standard within the acceptable probability threshold. In addition, there is no probability mutation in the edge of design space by probability-based method. Therefore, probability-based method is recommended for design space calculation. Copyright© by the Chinese Pharmaceutical Association.

A review of combined experimental and computational procedures for assessing biopolymer structure-process-property relationships.

PubMed

Gronau, Greta; Krishnaji, Sreevidhya T; Kinahan, Michelle E; Giesa, Tristan; Wong, Joyce Y; Kaplan, David L; Buehler, Markus J

2012-11-01

Tailored biomaterials with tunable functional properties are desirable for many applications ranging from drug delivery to regenerative medicine. To improve the predictability of biopolymer materials functionality, multiple design parameters need to be considered, along with appropriate models. In this article we review the state of the art of synthesis and processing related to the design of biopolymers, with an emphasis on the integration of bottom-up computational modeling in the design process. We consider three prominent examples of well-studied biopolymer materials - elastin, silk, and collagen - and assess their hierarchical structure, intriguing functional properties and categorize existing approaches to study these materials. We find that an integrated design approach in which both experiments and computational modeling are used has rarely been applied for these materials due to difficulties in relating insights gained on different length- and time-scales. In this context, multiscale engineering offers a powerful means to accelerate the biomaterials design process for the development of tailored materials that suit the needs posed by the various applications. The combined use of experimental and computational tools has a very broad applicability not only in the field of biopolymers, but can be exploited to tailor the properties of other polymers and composite materials in general. Copyright © 2012 Elsevier Ltd. All rights reserved.

Study on processing immiscible materials in zero gravity

NASA Technical Reports Server (NTRS)

Reger, J. L.; Mendelson, R. A.

1975-01-01

An experimental investigation was conducted to evaluate mixing immiscible metal combinations under several process conditions. Under one-gravity, these included thermal processing, thermal plus electromagnetic mixing, and thermal plus acoustic mixing. The same process methods were applied during free fall on the MSFC drop tower facility. The design is included of drop tower apparatus to provide the electromagnetic and acoustic mixing equipment, and a thermal model was prepared to design the specimen and cooling procedure. Materials systems studied were Ca-La, Cd-Ga and Al-Bi; evaluation of the processed samples included the morphology and electronic property measurements. The morphology was developed using optical and scanning electron microscopy and microprobe analyses. Electronic property characterization of the superconducting transition temperatures were made using an impedance change-tuned coil method.

Wearable Networked Sensing for Human Mobility and Activity Analytics: A Systems Study.

PubMed

Dong, Bo; Biswas, Subir

2012-01-01

This paper presents implementation details, system characterization, and the performance of a wearable sensor network that was designed for human activity analysis. Specific machine learning mechanisms are implemented for recognizing a target set of activities with both out-of-body and on-body processing arrangements. Impacts of energy consumption by the on-body sensors are analyzed in terms of activity detection accuracy for out-of-body processing. Impacts of limited processing abilities in the on-body scenario are also characterized in terms of detection accuracy, by varying the background processing load in the sensor units. Through a rigorous systems study, it is shown that an efficient human activity analytics system can be designed and operated even under energy and processing constraints of tiny on-body wearable sensors.

Effects of Cloud-Based m-Learning on Student Creative Performance in Engineering Design

ERIC Educational Resources Information Center

Chang, Yu-Shan; Chen, Si-Yi; Yu, Kuang-Chao; Chu, Yih-Hsien; Chien, Yu-Hung

2017-01-01

This study explored the effects of cloud-based m-learning on students' creative processes and products in engineering design. A nonequivalent pretest-posttest design was adopted, and 62 university students from Taipei City, Taiwan, were recruited as research participants in the study. The results showed that cloud-based m-learning had a positive…

Collaborative Invention in Computer Prototype Design: Negotiating Group Processes and Artifacts.

ERIC Educational Resources Information Center

Werner, Mark

A study looked at four groups of mostly senior graphic and industrial design students in their final semester capstone course--a collaborative studio project intended to give them the opportunity to apply their design expertise to real-world problems for real clients. The study examined the ways in which one of these groups used arguments to…

Interplay of Computer and Paper-Based Sketching in Graphic Design

ERIC Educational Resources Information Center

Pan, Rui; Kuo, Shih-Ping; Strobel, Johannes

2013-01-01

The purpose of this study is to investigate student designers' attitude and choices towards the use of computers and paper sketches when involved in a graphic design process. 65 computer graphic technology undergraduates participated in this research. A mixed method study with survey and in-depth interviews was applied to answer the research…

Creating Learning Environment Connecting Engineering Design and 3D Printing

NASA Astrophysics Data System (ADS)

Pikkarainen, Ari; Salminen, Antti; Piili, Heidi

Engineering education in modern days require continuous development in didactics, pedagogics and used practical methods. 3D printing provides excellent opportunity to connect different engineering areas into practice and produce learning by doing applications. The 3D-printing technology used in this study is FDM (Fused deposition modeling). FDM is the most used 3D-printing technology by commercial numbers at the moment and the qualities of the technology makes it popular especially in academic environments. For achieving the best result possible, students will incorporate the principles of DFAM (Design for additive manufacturing) into their engineering design studies together with 3D printing. This paper presents a plan for creating learning environment for mechanical engineering students combining the aspects of engineering design, 3D-CAD learning and AM (additive manufacturing). As a result, process charts for carrying out the 3D printing process from technological point of view and design process for AM from engineering design point of view were created. These charts are used in engineering design education. The learning environment is developed to work also as a platform for Bachelor theses, work-training environment for students, prototyping service centre for cooperation partners and source of information for mechanical engineering education in Lapland University of Applied Sciences.

Advanced digital SAR processing study

NASA Technical Reports Server (NTRS)

Martinson, L. W.; Gaffney, B. P.; Liu, B.; Perry, R. P.; Ruvin, A.

1982-01-01

A highly programmable, land based, real time synthetic aperture radar (SAR) processor requiring a processed pixel rate of 2.75 MHz or more in a four look system was designed. Variations in range and azimuth compression, number of looks, range swath, range migration and SR mode were specified. Alternative range and azimuth processing algorithms were examined in conjunction with projected integrated circuit, digital architecture, and software technologies. The advaced digital SAR processor (ADSP) employs an FFT convolver algorithm for both range and azimuth processing in a parallel architecture configuration. Algorithm performace comparisons, design system design, implementation tradeoffs and the results of a supporting survey of integrated circuit and digital architecture technologies are reported. Cost tradeoffs and projections with alternate implementation plans are presented.

Solar energy for process heat: Design/cost studies of four industrial retrofit applications

NASA Technical Reports Server (NTRS)

French, R. L.; Bartera, R. E.

1978-01-01

Five specific California plants with potentially attractive solar applications were identified in a process heat survey. These five plants were visited, process requirements evaluated, and conceptual solar system designs were generated. Four DOE (ERDA) sponsored solar energy system demonstration projects were also reviewed and compared to the design/cost cases included in this report. In four of the five cases investigated, retrofit installations providing significant amounts of thermal energy were found to be feasible. The fifth was rejected because of the condition of the building involved, but the process (soap making) appears to be an attractive potential solar application. Costs, however, tend to be high. Several potential areas for cost reduction were identified including larger collector modules and higher duty cycles.

Earthdata Search Usability Study Process

NASA Technical Reports Server (NTRS)

Reese, Mark

2016-01-01

User experience (UX) design is the process of enhancing user satisfaction by improving various aspects of the user's interaction with an application or website. One aspect of UX design is usability, or the extent to which an application can be used to to accomplish tasks efficiently, effectively, and with satisfaction. NASA's Earthdata Search Client recently underwent a focused usability testing project to measure usability and gain valuable user feedback and insights to increase usability for its end-users. This presentation focuses on the process by which the usability tests were administered and the lessons learned throughout the process.

Pollution balance method and the demonstration of its application to minimizing waste in a biochemical process

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hilaly, A.K.; Sikdar, S.K.

In this study, the authors introduced several modifications to the WAR (waste reduction) algorithm developed earlier. These modifications were made for systematically handling sensitivity analysis and various tasks of waste minimization. A design hierarchy was formulated to promote appropriate waste reduction tasks at designated levels of the hierarchy. A sensitivity coefficient was used to measure the relative impacts of process variables on the pollution index of a process. The use of the WAR algorithm was demonstrated by a fermentation process for making penicillin.

On Intelligent Design and Planning Method of Process Route Based on Gun Breech Machining Process

NASA Astrophysics Data System (ADS)

Hongzhi, Zhao; Jian, Zhang

2018-03-01

The paper states an approach of intelligent design and planning of process route based on gun breech machining process, against several problems, such as complex machining process of gun breech, tedious route design and long period of its traditional unmanageable process route. Based on gun breech machining process, intelligent design and planning system of process route are developed by virtue of DEST and VC++. The system includes two functional modules--process route intelligent design and its planning. The process route intelligent design module, through the analysis of gun breech machining process, summarizes breech process knowledge so as to complete the design of knowledge base and inference engine. And then gun breech process route intelligently output. On the basis of intelligent route design module, the final process route is made, edited and managed in the process route planning module.

Better cancer biomarker discovery through better study design.

PubMed

Rundle, Andrew; Ahsan, Habibul; Vineis, Paolo

2012-12-01

High-throughput laboratory technologies coupled with sophisticated bioinformatics algorithms have tremendous potential for discovering novel biomarkers, or profiles of biomarkers, that could serve as predictors of disease risk, response to treatment or prognosis. We discuss methodological issues in wedding high-throughput approaches for biomarker discovery with the case-control study designs typically used in biomarker discovery studies, especially focusing on nested case-control designs. We review principles for nested case-control study design in relation to biomarker discovery studies and describe how the efficiency of biomarker discovery can be effected by study design choices. We develop a simulated prostate cancer cohort data set and a series of biomarker discovery case-control studies nested within the cohort to illustrate how study design choices can influence biomarker discovery process. Common elements of nested case-control design, incidence density sampling and matching of controls to cases are not typically factored correctly into biomarker discovery analyses, inducing bias in the discovery process. We illustrate how incidence density sampling and matching of controls to cases reduce the apparent specificity of truly valid biomarkers 'discovered' in a nested case-control study. We also propose and demonstrate a new case-control matching protocol, we call 'antimatching', that improves the efficiency of biomarker discovery studies. For a valid, but as yet undiscovered, biomarker(s) disjunctions between correctly designed epidemiologic studies and the practice of biomarker discovery reduce the likelihood that true biomarker(s) will be discovered and increases the false-positive discovery rate. © 2012 The Authors. European Journal of Clinical Investigation © 2012 Stichting European Society for Clinical Investigation Journal Foundation.

Double jeopardy in inferring cognitive processes

PubMed Central

Fific, Mario

2014-01-01

Inferences we make about underlying cognitive processes can be jeopardized in two ways due to problematic forms of aggregation. First, averaging across individuals is typically considered a very useful tool for removing random variability. The threat is that averaging across subjects leads to averaging across different cognitive strategies, thus harming our inferences. The second threat comes from the construction of inadequate research designs possessing a low diagnostic accuracy of cognitive processes. For that reason we introduced the systems factorial technology (SFT), which has primarily been designed to make inferences about underlying processing order (serial, parallel, coactive), stopping rule (terminating, exhaustive), and process dependency. SFT proposes that the minimal research design complexity to learn about n number of cognitive processes should be equal to 2n. In addition, SFT proposes that (a) each cognitive process should be controlled by a separate experimental factor, and (b) The saliency levels of all factors should be combined in a full factorial design. In the current study, the author cross combined the levels of jeopardies in a 2 × 2 analysis, leading to four different analysis conditions. The results indicate a decline in the diagnostic accuracy of inferences made about cognitive processes due to the presence of each jeopardy in isolation and when combined. The results warrant the development of more individual subject analyses and the utilization of full-factorial (SFT) experimental designs. PMID:25374545

Finite element modelling of chain-die forming for ultra-high strength steel

NASA Astrophysics Data System (ADS)

Majji, Raju; Xiang, Yang; Ding, Scott; Yang, Chunhui

2017-10-01

There has been a high demand for weight reduction in automotive vehicles while maintaining passenger safety. A potential steel material to achieve this is Ultra High Strength Steel (UHSS). As a high strength material, it is difficult to be formed with desired profiles using traditional sheet metal forming processes such as Cold Roll Forming. To overcome this problem, a potentially alternative solution is Chain-die Forming (CDF), recently developed. The basic principal of the CDF is to fully combine roll forming and bending processes. The main advantage of this process is the elongated deformation length that significantly increases effective roll radius. This study focuses on identifying issues with the CDF by using CAD modelling, Motion Analysis and Finite Element Analysis (FEA) to devise solutions and construct a more reliable process in an optimal design sense. Some attempts on finite element modelling and simulation of the CDF were conducted using relatively simple models in literature and the research was still not sufficient enough for optimal design of a typical CDF for UHSS. Therefore two numerical models of Chain-die Forming process are developed in this study, including a) one having a set of rolls similar to roll forming but with a large radius, i.e., 20 meters; and b) the other one with dies and punch segments similar to a typical CDF machine. As a case study, to form a 60° channel with single pass was conducted using these two devised models for a comparison. The obtained numerical results clearly show the CDF could generate less residual stress, low strain and small springback of a single pass for the 60° UHSS channel. The design analysis procedure proposed in this study could greatly help the mechanical designers to devise a cost-effective and reliable CDF process for forming UHSS.

Effects of a school reform on longitudinal stability of students' preferences with regard to education.

PubMed

Könings, Karen D; Brand-Gruwel, Saskia; Elen, Jan

2012-09-01

Students' perspective on education is of crucial importance for its effectivity, but students' opinions are seldom acknowledged by teachers and designers. Student participation in the educational design process could be a suitable tool to better take students' preferences into account. However, for effective participatory design, it is necessary to know whether students have stable preferences for the design of their education. Changeability of preferences would require a more continuing design process allowing continuous adaptations. This longitudinal survey study aimed to determine the changeability over time of students' preferences for different aspects of a learning environment. Additionally, causes of possible changes in preferences are investigated. The participants were 1,335 high school students of five schools for secondary education in the Netherlands, joining this study during a period of 2 years. Data about students' preferences were collected at three moments, using the Inventory of Perceived Study Environment Extended. Learning-related student characteristics, such as processing strategies and motivational orientations, were measured with the Inventory of Learning Styles. Additionally, data on learning performances were collected. The results showed stability on preferences for almost all studied characteristics of the learning environment. Particularly remarkable was a drop in desirability for student autonomy. This was larger for students with a certificate-oriented motivation and smaller for self-regulated students. Additionally, poorly performing students had a larger decrease in preference for autonomy. The stability on most aspects supports that participatory design might result in fairly stable instructional designs, although caution is needed with respect to student autonomy. ©2011 The British Psychological Society.

Virtual design and construction of plumbing systems

NASA Astrophysics Data System (ADS)

Filho, João Bosco P. Dantas; Angelim, Bruno Maciel; Guedes, Joana Pimentel; de Castro, Marcelo Augusto Farias; Neto, José de Paula Barros

2016-12-01

Traditionally, the design coordination process is carried out by overlaying and comparing 2D drawings made by different project participants. Detecting information errors from a composite drawing is especially challenging and error prone. This procedure usually leaves many design errors undetected until construction begins, and typically lead to rework. Correcting conflict issues, which were not identified during design and coordination phase, reduces the overall productivity for everyone involved in the construction process. The identification of construction issues in the field generate Request for Information (RFIs) that is one of delays causes. The application of Virtual Design and Construction (VDC) tools to the coordination processes can bring significant value to architecture, structure, and mechanical, electrical, and plumbing (MEP) designs in terms of a reduced number of errors undetected and requests for information. This paper is focused on evaluating requests for information (RFI) associated with water/sanitary facilities of a BIM model. Thus, it is expected to add improvements of water/sanitary facility designs, as well as to assist the virtual construction team to notice and identify design problems. This is an exploratory and descriptive research. A qualitative methodology is used. This study adopts RFI's classification in six analyzed categories: correction, omission, validation of information, modification, divergence of information and verification. The results demonstrate VDC's contribution improving the plumbing system designs. Recommendations are suggested to identify and avoid these RFI types in plumbing system design process or during virtual construction.

How do design features influence consumer attention when looking for nutritional information on food labels? Results from an eye-tracking study on pan bread labels.

PubMed

Antúnez, Lucía; Vidal, Leticia; Sapolinski, Alejandra; Giménez, Ana; Maiche, Alejandro; Ares, Gastón

2013-08-01

The aim of this work was to evaluate consumer visual processing of food labels when evaluating the salt content of pan bread labels and to study the influence of label design and nutritional labelling format on consumer attention. A total of 16 pan bread labels, designed according to a full factorial design, were presented to 52 participants, who were asked to decide whether the sodium content of each label was medium or low, while their eye movements were recorded using an eye tracker. Results showed that most participants looked at nutrition labels and the traffic light system to conclude on the salt content of the labels. However, the average percentage of participants who looked at the actual sodium content was much lower. Nutrition information format affected participants' processing of nutrition information. Among other effects, the inclusion of the traffic light system increased participants' attention towards some kind of nutrition information and facilitated its processing, but not its understanding.

Head-Up; An interdisciplinary, participatory and co-design process informing the development of a novel head and neck support for people living with progressive neck muscle weakness.

PubMed

Reed, Heath; Langley, Joe; Stanton, Andy; Heron, Nicola; Clarke, Zoe; Judge, Simon; McCarthy, Avril; Squire, Gill; Quinn, Ann; Wells, Oliver; Tindale, Wendy; Baxter, Susan; Shaw, Pamela J; McDermott, Christopher J

2014-01-01

This paper presents the Head-Up project, that aims to provide innovative head support to help improve posture, relieve pain and aid communication for people living with progressive neck muscle weakness. The initial focus is motor neurone disease. The case study illustrates collaborative, interdisciplinary research and new product development underpinned by participatory design. The study was initiated by a 2-day stakeholder workshop followed by early proof-of-concept modelling and patient need evidence building. The work subsequently led to a successful NIHR i4i application funding a 24-month iterative design process, patenting, CE marking and clinical evaluation. The evaluation has informed amendments to the proposed design refered to here as the Sheffield Support Snood (SSS). The outcome positively demonstrates use and performance improvements over current neck orthoses and the process of multidisciplinary and user engagement has created a sense of ownership by MND participants, who have since acted as advocates for the product.

Factors impeding flexible inpatient unit design.

PubMed

Pati, Debajyoti; Evans, Jennie; Harvey, Thomas E; Bazuin, Doug

2012-01-01

To identify and examine factors extraneous to the design decision-making process that could impede the optimization of flexibility on inpatient units. A 2006 empirical study to identify domains of design decisions that affect flexibility on inpatient units found some indication in the context of the acuity-adaptable operational model that factors extraneous to the design process could have negatively influenced the successful implementation of the model. This raised questions regarding extraneous factors that might influence the successful optimization of flexibility. An exploratory, qualitative method was adopted to examine the question. Stakeholders from five recently built acute care inpatient units participated in the study, which involved three types of data collection: (1) verbal protocol data from a gaming session; (2) in-depth semi-structured interviews; and (3) shadowing frontline personnel. Data collection was conducted between June 2009 and November 2010. The study revealed at least nine factors extraneous to the design process that have the potential to hinder the optimization of flexibility in four domains: (1) systemic; (2) cultural; (3) human; and (4) financial. Flexibility is critical to hospital operations in the new healthcare climate, where cost reduction constitutes a vital target. From this perspective, flexibility and efficiency strategies can be influenced by (1) return on investment, (2) communication, (3) culture change, and (4) problem definition. Extraneous factors identified in this study could also affect flexibility in other care settings; therefore, these findings may be viewed from the overall context of hospital design.

Integrated Application of Quality-by-Design Principles to Drug Product Development: A Case Study of Brivanib Alaninate Film-Coated Tablets.

PubMed

Badawy, Sherif I F; Narang, Ajit S; LaMarche, Keirnan R; Subramanian, Ganeshkumar A; Varia, Sailesh A; Lin, Judy; Stevens, Tim; Shah, Pankaj A

2016-01-01

Modern drug product development is expected to follow quality-by-design (QbD) paradigm. At the same time, although there are several issue-specific examples in the literature that demonstrate the application of QbD principles, a holistic demonstration of the application of QbD principles to drug product development and control strategy, is lacking. This article provides an integrated case study on the systematic application of QbD to product development and demonstrates the implementation of QbD concepts in the different aspects of product and process design for brivanib alaninate film-coated tablets. Using a risk-based approach, the strategy for development entailed identification of product critical quality attributes (CQAs), assessment of risks to the CQAs, and performing experiments to understand and mitigate identified risks. Quality risk assessments and design of experiments were performed to understand the quality of the input raw materials required for a robust formulation and the impact of manufacturing process parameters on CQAs. In addition to the material property and process parameter controls, the proposed control strategy includes use of process analytical technology and conventional analytical tests to control in-process material attributes and ensure quality of the final product. Copyright © 2016. Published by Elsevier Inc.

Design of the North Carolina Prostate Cancer Comparative Effectiveness and Survivorship Study (NC ProCESS).

PubMed

Chen, Ronald C; Carpenter, William R; Kim, Mimi; Hendrix, Laura H; Agans, Robert P; Meyer, Anne-Marie; Hoffmeyer, Anna; Reeve, Bryce B; Nielsen, Matthew E; Usinger, Deborah S; Strigo, Tara S; Jackman, Anne M; Anderson, Mary; Godley, Paul A

2015-01-01

The North Carolina Prostate Cancer Comparative Effectiveness & Survivorship Study (NC ProCESS) was designed in collaboration with stakeholders to compare the effectiveness of different treatment options for localized prostate cancer. Using the Rapid Case Ascertainment system of the North Carolina Central Cancer Registry, 1,419 patients (57% of eligible) with newly-diagnosed localized prostate cancer were enrolled from January 2011 to June 2013, on average 5 weeks after diagnosis. All participants were enrolled prior to treatment and this population-based cohort is sociodemographically diverse. Prospective follow-up continues to collect data on treatments received, disease control, survival and patient-reported outcomes. This study highlights several important considerations regarding stakeholder involvement, study design and generalizability regarding comparative effectiveness research in prostate cancer.

Evaluating process in child and family interventions: aggression prevention as an example.

PubMed

Tolan, Patrick H; Hanish, Laura D; McKay, Mary M; Dickey, Mitchell H

2002-06-01

This article reports on 2 studies designed to develop and validate a set of measures for use in evaluating processes of child and family interventions. In Study 1 responses from 187 families attending an outpatient clinic for child behavior problems were factor analyzed to identify scales, consistent across sources: Alliance (Satisfactory Relationship with Interventionist and Program Satisfaction), Parenting Skill Attainment, Child Cooperation During Session, Child Prosocial Behavior, and Child Aggressive Behavior. Study 2 focused on patterns of scale scores among 78 families taking part in a 22-week preventive intervention designed to affect family relationships, parenting, and child antisocial and prosocial behaviors. The factor structure identified in Study 1 was replicated. Scale construct validity was demonstrated through across-source convergence, sensitivity to intervention change, and ability to discriminate individual differences. Path analysis validated the scales' utility in explaining key aspects of the intervention process. Implications for evaluating processes in family interventions are discussed.

The Rocket Equation Improvement under ICF Implosion Experiment

NASA Astrophysics Data System (ADS)

Wang, Yanbin; Zheng, Zhijian

2013-10-01

The ICF explosion process has been studied in details. The rocket equation has been improved in explosive process by introducing the pressure parameter of fuel. Some methods could be drawn by the improved rocket equation. And the methods could be used to improve ICF target design, driving pulse design and experimental design. The First is to increase ablation pressure. The second is to decrease pressure of fuel. The third is to use larger diameter of target sphere. And the forth is to a shorten driving pulse.

Ergonomics and design: its principles applied in the industry.

PubMed

Tavares, Ademario Santos; Silva, Francisco Nilson da

2012-01-01

Industrial Design encompasses both product development and optimization of production process. In this sense, Ergonomics plays a fundamental role, because its principles, methods and techniques can help operators to carry out their tasks most successfully. A case study carried out in an industry shows that the interaction among Design, Production Engineering and Materials Engineering departments may improve some aspects concerned security, comfort, efficiency and performance. In this process, Ergonomics had shown to be of essential importance to strategic decision making to the improvement of production section.

Human-Centered Design as an Approach for Place-Based Innovation in Public Health: A Case Study from Oakland, California.

PubMed

Vechakul, Jessica; Shrimali, Bina Patel; Sandhu, Jaspal S

2015-12-01

This case study provides a high-level overview of the human-centered design (HCD) or "design thinking" process and its relevance to public health. The Best Babies Zone (BBZ) initiative is a multi-year project aimed at reducing inequities in infant mortality rates. In 2012, BBZ launched pilot programs in three US cities: Cincinnati, Ohio; New Orleans, Louisiana; and Oakland, California. The Alameda County Public Health Department (ACPHD), the lead for the Oakland BBZ site, identified HCD as a promising approach for addressing the social and economic conditions that are important drivers of health inequities. HCD is a process for creating innovative products, services, and strategies that prioritizes the needs of the intended population. ACPHD partnered with the Gobee Group (a social innovation design consultancy) to develop the Design Sprint. The Design Sprint was a 12-week pilot in which 14 professionals from nine organizations used the HCD process to develop concepts for stimulating a vibrant local economy in the Oakland Best Babies Zone. Thirty- to sixty-minute semi-structured interviews were conducted with all 14 individuals involved in the Design Sprint. With the exception of one interview, the interviews were audio-recorded, transcribed, and inductively coded to identify themes. Our experience suggests that HCD can: enhance community engagement; expedite the timeframe for challenge identification, program design, and implementation; and create innovative programs that address complex challenges.

An approach to quantitative sustainability assessment in the early stages of process design.

PubMed

Tugnoli, Alessandro; Santarelli, Francesco; Cozzani, Valerio

2008-06-15

A procedure was developed for the quantitative assessment of key performance indicators suitable for the sustainability analysis of alternative processes, mainly addressing the early stages of process design. The methodology was based on the calculation of a set of normalized impact indices allowing a direct comparison of the additional burden of each process alternative on a selected reference area. Innovative reference criteria were developed to compare and aggregate the impact indicators on the basis of the site-specific impact burden and sustainability policy. An aggregation procedure also allows the calculation of overall sustainability performance indicators and of an "impact fingerprint" of each process alternative. The final aim of the method is to support the decision making process during process development, providing a straightforward assessment of the expected sustainability performances. The application of the methodology to case studies concerning alternative waste disposal processes allowed a preliminary screening of the expected critical sustainability impacts of each process. The methodology was shown to provide useful results to address sustainability issues in the early stages of process design.

Development of a Web-Based Health Care Intervention for Patients With Heart Disease: Lessons Learned From a Participatory Design Study

PubMed Central

2017-01-01

Background The use of telemedicine technologies in health care has increased substantially, together with a growing interest in participatory design methods when developing telemedicine approaches. Objective We present lessons learned from a case study involving patients with heart disease and health care professionals in the development of a personalized Web-based health care intervention. Methods We used a participatory design approach inspired by the method for feasibility studies in software development. We collected qualitative data using multiple methods in 3 workshops and analyzed the data using thematic analysis. Participants were 7 patients with diagnosis of heart disease, 2 nurses, 1 physician, 2 systems architects, 3 moderators, and 3 observers. Results We present findings in 2 parts. (1) Outcomes of the participatory design process: users gave valuable feedback on ease of use of the platforms’ tracking tools, platform design, terminology, and insights into patients’ monitoring needs, information and communication technologies skills, and preferences for self-management tools. (2) Experiences from the participatory design process: patients and health care professionals contributed different perspectives, with the patients using an experience-based approach and the health care professionals using a more attitude-based approach. Conclusions The essential lessons learned concern planning and organization of workshops, including the finding that patients engaged actively and willingly in a participatory design process, whereas it was more challenging to include and engage health care professionals. PMID:28526674

Quality by design approach: application of artificial intelligence techniques of tablets manufactured by direct compression.

PubMed

Aksu, Buket; Paradkar, Anant; de Matas, Marcel; Ozer, Ozgen; Güneri, Tamer; York, Peter

2012-12-01

The publication of the International Conference of Harmonization (ICH) Q8, Q9, and Q10 guidelines paved the way for the standardization of quality after the Food and Drug Administration issued current Good Manufacturing Practices guidelines in 2003. "Quality by Design", mentioned in the ICH Q8 guideline, offers a better scientific understanding of critical process and product qualities using knowledge obtained during the life cycle of a product. In this scope, the "knowledge space" is a summary of all process knowledge obtained during product development, and the "design space" is the area in which a product can be manufactured within acceptable limits. To create the spaces, artificial neural networks (ANNs) can be used to emphasize the multidimensional interactions of input variables and to closely bind these variables to a design space. This helps guide the experimental design process to include interactions among the input variables, along with modeling and optimization of pharmaceutical formulations. The objective of this study was to develop an integrated multivariate approach to obtain a quality product based on an understanding of the cause-effect relationships between formulation ingredients and product properties with ANNs and genetic programming on the ramipril tablets prepared by the direct compression method. In this study, the data are generated through the systematic application of the design of experiments (DoE) principles and optimization studies using artificial neural networks and neurofuzzy logic programs.

A method to accelerate creation of plasma etch recipes using physics and Bayesian statistics

NASA Astrophysics Data System (ADS)

Chopra, Meghali J.; Verma, Rahul; Lane, Austin; Willson, C. G.; Bonnecaze, Roger T.

2017-03-01

Next generation semiconductor technologies like high density memory storage require precise 2D and 3D nanopatterns. Plasma etching processes are essential to achieving the nanoscale precision required for these structures. Current plasma process development methods rely primarily on iterative trial and error or factorial design of experiment (DOE) to define the plasma process space. Here we evaluate the efficacy of the software tool Recipe Optimization for Deposition and Etching (RODEo) against standard industry methods at determining the process parameters of a high density O2 plasma system with three case studies. In the first case study, we demonstrate that RODEo is able to predict etch rates more accurately than a regression model based on a full factorial design while using 40% fewer experiments. In the second case study, we demonstrate that RODEo performs significantly better than a full factorial DOE at identifying optimal process conditions to maximize anisotropy. In the third case study we experimentally show how RODEo maximizes etch rates while using half the experiments of a full factorial DOE method. With enhanced process predictions and more accurate maps of the process space, RODEo reduces the number of experiments required to develop and optimize plasma processes.

An Exploratory Study of Cost Engineering in Axiomatic Design: Creation of the Cost Model Based on an FR-DP Map

NASA Technical Reports Server (NTRS)

Lee, Taesik; Jeziorek, Peter

2004-01-01

Large complex projects cost large sums of money throughout their life cycle for a variety of reasons and causes. For such large programs, the credible estimation of the project cost, a quick assessment of the cost of making changes, and the management of the project budget with effective cost reduction determine the viability of the project. Cost engineering that deals with these issues requires a rigorous method and systematic processes. This paper introduces a logical framework to a&e effective cost engineering. The framework is built upon Axiomatic Design process. The structure in the Axiomatic Design process provides a good foundation to closely tie engineering design and cost information together. The cost framework presented in this paper is a systematic link between the functional domain (FRs), physical domain (DPs), cost domain (CUs), and a task/process-based model. The FR-DP map relates a system s functional requirements to design solutions across all levels and branches of the decomposition hierarchy. DPs are mapped into CUs, which provides a means to estimate the cost of design solutions - DPs - from the cost of the physical entities in the system - CUs. The task/process model describes the iterative process ot-developing each of the CUs, and is used to estimate the cost of CUs. By linking the four domains, this framework provides a superior traceability from requirements to cost information.

High productivity chromatography refolding process for Hepatitis B Virus X (HBx) protein guided by statistical design of experiment studies.

PubMed

Basu, Anindya; Leong, Susanna Su Jan

2012-02-03

The Hepatitis B Virus X (HBx) protein is a potential therapeutic target for the treatment of hepatocellular carcinoma. However, consistent expression of the protein as insoluble inclusion bodies in bacteria host systems has largely hindered HBx manufacturing via economical biosynthesis routes, thereby impeding the development of anti-HBx therapeutic strategies. To eliminate this roadblock, this work reports the development of the first 'chromatography refolding'-based bioprocess for HBx using immobilised metal affinity chromatography (IMAC). This process enabled production of HBx at quantities and purity that facilitate their direct use in structural and molecular characterization studies. In line with the principles of quality by design (QbD), we used a statistical design of experiments (DoE) methodology to design the optimum process which delivered bioactive HBx at a productivity of 0.21 mg/ml/h at a refolding yield of 54% (at 10 mg/ml refolding concentration), which was 4.4-fold higher than that achieved in dilution refolding. The systematic DoE methodology adopted for this study enabled us to obtain important insights into the effect of different bioprocess parameters like the effect of buffer exchange gradients on HBx productivity and quality. Such a bioprocess design approach can play a pivotal role in developing intensified processes for other novel proteins, and hence helping to resolve validation and speed-to-market challenges faced by the biopharmaceutical industry today. Copyright © 2011 Elsevier B.V. All rights reserved.

Optimisation of warpage on plastic injection moulding part using response surface methodology (RSM)

NASA Astrophysics Data System (ADS)

Miza, A. T. N. A.; Shayfull, Z.; Nasir, S. M.; Fathullah, M.; Rashidi, M. M.

2017-09-01

The warpage is often encountered which occur during injection moulding process of thin shell part depending the process condition. The statistical design of experiment method which are Integrating Finite Element (FE) Analysis, moldflow analysis and response surface methodology (RSM) are the stage of few ways in minimize the warpage values of x,y and z on thin shell plastic parts that were investigated. A battery cover of a remote controller is one of the thin shell plastic part that produced by using injection moulding process. The optimum process condition parameter were determined as to achieve the minimum warpage from being occur. Packing pressure, Cooling time, Melt temperature and Mould temperature are 4 parameters that considered in this study. A two full factorial experimental design was conducted in Design Expert of RSM analysis as to combine all these parameters study. FE analysis result gain from analysis of variance (ANOVA) method was the one of the important process parameters influenced warpage. By using RSM, a predictive response surface model for warpage data will be shown.

Economic Statistical Design of Integrated X-bar-S Control Chart with Preventive Maintenance and General Failure Distribution

PubMed Central

Caballero Morales, Santiago Omar

2013-01-01

The application of Preventive Maintenance (PM) and Statistical Process Control (SPC) are important practices to achieve high product quality, small frequency of failures, and cost reduction in a production process. However there are some points that have not been explored in depth about its joint application. First, most SPC is performed with the X-bar control chart which does not fully consider the variability of the production process. Second, many studies of design of control charts consider just the economic aspect while statistical restrictions must be considered to achieve charts with low probabilities of false detection of failures. Third, the effect of PM on processes with different failure probability distributions has not been studied. Hence, this paper covers these points, presenting the Economic Statistical Design (ESD) of joint X-bar-S control charts with a cost model that integrates PM with general failure distribution. Experiments showed statistically significant reductions in costs when PM is performed on processes with high failure rates and reductions in the sampling frequency of units for testing under SPC. PMID:23527082

Designing a Language Study.

ERIC Educational Resources Information Center

Brown, James Dean

Some issues in the design of classroom research on second language teaching are discussed, with the intention of helping the researcher avoid conceptual pitfalls that may cripple the study later in the process. This begins with an examination of concerns in sampling, including definition of a population to be studied, alternative sampling…

75 FR 33311 - Guidance for Industry on Bioequivalence Recommendations for Specific Products; Availability

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-11

... available recommendations on how to design product- specific bioequivalence (BE) studies to support... meaningful opportunity for the public to consider and comment on product-specific BE study recommendations... available recommendations on how to design product-specific BE studies to support ANDAs. Under this process...

Integrating Thermal Tools Into the Mechanical Design Process

NASA Technical Reports Server (NTRS)

Tsuyuki, Glenn T.; Siebes, Georg; Novak, Keith S.; Kinsella, Gary M.

1999-01-01

The intent of mechanical design is to deliver a hardware product that meets or exceeds customer expectations, while reducing cycle time and cost. To this end, an integrated mechanical design process enables the idea of parallel development (concurrent engineering). This represents a shift from the traditional mechanical design process. With such a concurrent process, there are significant issues that have to be identified and addressed before re-engineering the mechanical design process to facilitate concurrent engineering. These issues also assist in the integration and re-engineering of the thermal design sub-process since it resides within the entire mechanical design process. With these issues in mind, a thermal design sub-process can be re-defined in a manner that has a higher probability of acceptance, thus enabling an integrated mechanical design process. However, the actual implementation is not always problem-free. Experience in applying the thermal design sub-process to actual situations provides the evidence for improvement, but more importantly, for judging the viability and feasibility of the sub-process.

150-nm DR contact holes die-to-database inspection

NASA Astrophysics Data System (ADS)

Kuo, Shen C.; Wu, Clare; Eran, Yair; Staud, Wolfgang; Hemar, Shirley; Lindman, Ofer

2000-07-01

Using a failure analysis-driven yield enhancements concept, based on an optimization of the mask manufacturing process and UV reticle inspection is studied and shown to improve the contact layer quality. This is achieved by relating various manufacturing processes to very fine tuned contact defect detection. In this way, selecting an optimized manufacturing process with fine-tuned inspection setup is achieved in a controlled manner. This paper presents a study, performed on a specially designed test reticle, which simulates production contact layers of design rule 250nm, 180nm and 150nm. This paper focuses on the use of advanced UV reticle inspection techniques as part of the process optimization cycle. Current inspection equipment uses traditional and insufficient methods of small contact-hole inspection and review.

Development of a fast, lean and agile direct pelletization process using experimental design techniques.

PubMed

Politis, Stavros N; Rekkas, Dimitrios M

2017-04-01

A novel hot melt direct pelletization method was developed, characterized and optimized, using statistical thinking and experimental design tools. Mixtures of carnauba wax (CW) and HPMC K100M were spheronized using melted gelucire 50-13 as a binding material (BM). Experimentation was performed sequentially; a fractional factorial design was set up initially to screen the factors affecting the process, namely spray rate, quantity of BM, rotor speed, type of rotor disk, lubricant-glidant presence, additional spheronization time, powder feeding rate and quantity. From the eight factors assessed, three were further studied during process optimization (spray rate, quantity of BM and powder feeding rate), at different ratios of the solid mixture of CW and HPMC K100M. The study demonstrated that the novel hot melt process is fast, efficient, reproducible and predictable. Therefore, it can be adopted in a lean and agile manufacturing setting for the production of flexible pellet dosage forms with various release rates easily customized between immediate and modified delivery.

Experimental Design and Interpretation of Functional Neuroimaging Studies of Cognitive Processes

PubMed Central

Caplan, David

2008-01-01

This article discusses how the relation between experimental and baseline conditions in functional neuroimaging studies affects the conclusions that can be drawn from a study about the neural correlates of components of the cognitive system and about the nature and organization of those components. I argue that certain designs in common use—in particular the contrast of qualitatively different representations that are processed at parallel stages of a functional architecture—can never identify the neural basis of a cognitive operation and have limited use in providing information about the nature of cognitive systems. Other types of designs—such as ones that contrast representations that are computed in immediately sequential processing steps and ones that contrast qualitatively similar representations that are parametrically related within a single processing stage—are more easily interpreted. PMID:17979122

Improving Science Process Skills for Primary School Students Through 5E Instructional Model-Based Learning

NASA Astrophysics Data System (ADS)

Choirunnisa, N. L.; Prabowo, P.; Suryanti, S.

2018-01-01

The main objective of this study is to describe the effectiveness of 5E instructional model-based learning to improve primary school students’ science process skills. The science process skills is important for students as it is the foundation for enhancing the mastery of concepts and thinking skills needed in the 21st century. The design of this study was experimental involving one group pre-test and post-test design. The result of this study shows that (1) the implementation of learning in both of classes, IVA and IVB, show that the percentage of learning implementation increased which indicates a better quality of learning and (2) the percentage of students’ science process skills test results on the aspects of observing, formulating hypotheses, determining variable, interpreting data and communicating increased as well.

The process of internationalization of the nursing and midwifery curriculum: A qualitative study.

PubMed

Abdul-Mumin, Khadizah H

2016-11-01

There is an abundance of literature on internationalization of curricula. However, research on how a curriculum is internationalized to accommodate non-mobile students studying in their home countries is limited. To describe the process undertaken by curriculum developers in internationalizing the Brunei nursing and midwifery curriculum through curriculum design. A descriptive qualitative research design. A nursing and midwifery higher education institution in Brunei. Seventeen nurse/midwife academics. Semi-structured interviews were conducted with 17 curriculum developers. Data were analyzed using thematic analysis. Four themes emerged: expectations of an internationalized curriculum; formation of a committee; benchmarking and setting standards; and designing the curriculum for internationalization. This study has implications for the development of an internationally-oriented curriculum that takes into account the cultural context of a specific country. The findings highlight the need to involve students in curriculum design, a practice that is not common in Brunei. Copyright © 2016 Elsevier Ltd. All rights reserved.

Understanding coping with cancer: how can qualitative research help?

PubMed

Chittem, Mahati

2014-01-01

Research in psycho-oncology investigates the psycho-social and emotional aspects of cancer and how this is related to health, well-being and overall patient care. Coping with cancer is a prime focus for researchers owing to its impact on patients' psychological processing and life in general. Research so far has focused mainly on quantitative study designs such as questionnaires to examine the coping strategies used by cancer patients. However, in order to gain a rich and deep understanding of the reasons, processes and types of strategies that patients use to deal with cancer, qualitative study designs are necessary. Few studies have used qualitative designs such as semi-structured interviews to explore coping with cancer. The current paper aims to review the suitability and benefits of using qualitative research designs to understand coping with cancer with the help of some key literature in psycho-oncology research.

Multiobjective optimization in structural design with uncertain parameters and stochastic processes

NASA Technical Reports Server (NTRS)

Rao, S. S.

1984-01-01

The application of multiobjective optimization techniques to structural design problems involving uncertain parameters and random processes is studied. The design of a cantilever beam with a tip mass subjected to a stochastic base excitation is considered for illustration. Several of the problem parameters are assumed to be random variables and the structural mass, fatigue damage, and negative of natural frequency of vibration are considered for minimization. The solution of this three-criteria design problem is found by using global criterion, utility function, game theory, goal programming, goal attainment, bounded objective function, and lexicographic methods. It is observed that the game theory approach is superior in finding a better optimum solution, assuming the proper balance of the various objective functions. The procedures used in the present investigation are expected to be useful in the design of general dynamic systems involving uncertain parameters, stochastic process, and multiple objectives.

The UARS and open data concept and analysis study. [upper atmosphere

NASA Technical Reports Server (NTRS)

Mittal, M.; Nebb, J.; Woodward, H.

1983-01-01

Alternative concepts for a common design for the UARS and OPEN Central Data Handling Facility (CDHF) are offered. Costs for alternative implementations of the UARS designs are presented, showing that the system design does not restrict the implementation to a single manufacturer. Processing demands on the alternative UARS CDHF implementations are then discussed. With this information at hand together with estimates for OPEN processing demands, it is shown that any shortfall in system capability for OPEN support can be remedied by either component upgrades or array processing attachments rather than a system redesign. In addition to a common system design, it is shown that there is significant potential for common software design, especially in the areas of data management software and non-user-unique production software. Archiving the CDHF data are discussed. Following that, cost examples for several modes of communications between the CDHF and Remote User Facilities are presented. Technology application is discussed.

On processing development for fabrication of fiber reinforced composite, part 2

NASA Technical Reports Server (NTRS)

Hou, Tan-Hung; Hou, Gene J. W.; Sheen, Jeen S.

1989-01-01

Fiber-reinforced composite laminates are used in many aerospace and automobile applications. The magnitudes and durations of the cure temperature and the cure pressure applied during the curing process have significant consequences for the performance of the finished product. The objective of this study is to exploit the potential of applying the optimization technique to the cure cycle design. Using the compression molding of a filled polyester sheet molding compound (SMC) as an example, a unified Computer Aided Design (CAD) methodology, consisting of three uncoupled modules, (i.e., optimization, analysis and sensitivity calculations), is developed to systematically generate optimal cure cycle designs. Various optimization formulations for the cure cycle design are investigated. The uniformities in the distributions of the temperature and the degree with those resulting from conventional isothermal processing conditions with pre-warmed platens. Recommendations with regards to further research in the computerization of the cure cycle design are also addressed.

A letter of intent for an experiment to study strong electromagnetic fields at RHIC via multiple electromagnetic processes

NASA Technical Reports Server (NTRS)

Fatyga, M.; Norbury, John W.

1992-01-01

An experimental program at the Relativistic Heavy Ion Collider (RHIC) which is designed to study nonperturbative aspects of electrodynamics is outlined. Additional possibilities for new studies of electrodynamics via multiple electromagnetic processes are also described.

Frontline Nurse Engagement and Empowerment: Characteristics and Processes for Building Leadership Capacity.

PubMed

Riley, Bettina H; Dearmon, Valorie; Mestas, Lisa; Buckner, Ellen B

2016-01-01

Improving health care quality is the responsibility of nurses at all levels of the organization. This article describes a study that examined frontline staff nurses' professional practice characteristics to advance leadership through the understanding of relationships among practice environment, quality improvement, and outcomes. The study design was a descriptive quantitative design at 2 time points. Findings support the use of research and quality processes to build leadership capacity required for positive resolution of interdisciplinary operational failures.

Teacher Learning in Collaborative Curriculum Design

ERIC Educational Resources Information Center

Voogt, J.; Westbroek, H.; Handelzalts, A.; Walraven, A.; McKenney, S.; Pieters, J.; de Vries, B.

2011-01-01

The Interconnected Model of Professional Growth (Clarke & Hollingsworth, 2002) was used to identify processes of teacher learning during the collaborative design of curriculum materials in the context of curriculum innovation. Nine published studies from six different countries about teachers' collaborative curriculum design were analyzed to…

End users transforming experiences into formal information and process models for personalised health interventions.

PubMed

Lindgren, Helena; Lundin-Olsson, Lillemor; Pohl, Petra; Sandlund, Marlene

2014-01-01

Five physiotherapists organised a user-centric design process of a knowledge-based support system for promoting exercise and preventing falls. The process integrated focus group studies with 17 older adults and prototyping. The transformation of informal medical and rehabilitation expertise and older adults' experiences into formal information and process models during the development was studied. As tool they used ACKTUS, a development platform for knowledge-based applications. The process became agile and incremental, partly due to the diversity of expectations and preferences among both older adults and physiotherapists, and the participatory approach to design and development. In addition, there was a need to develop the knowledge content alongside with the formal models and their presentations, which allowed the participants to test hands-on and evaluate the ideas, content and design. The resulting application is modular, extendable, flexible and adaptable to the individual end user. Moreover, the physiotherapists are able to modify the information and process models, and in this way further develop the application. The main constraint was found to be the lack of support for the initial phase of concept modelling, which lead to a redesigned user interface and functionality of ACKTUS.

Design Architecture of field-effect transistor with back gate electrode for biosensor application

NASA Astrophysics Data System (ADS)

Fathil, M. F. M.; Arshad, M. K. Md.; Hashim, U.; Ruslinda, A. R.; Gopinath, Subash C. B.; M. Nuzaihan M., N.; Ayub, R. M.; Adzhri, R.; Zaki, M.; Azman, A. H.

2016-07-01

This paper presents the preparation method of photolithography chrome mask design used in fabrication process of field-effect transistor with back gate biasing based biosensor. Initially, the chrome masks are designed by studying the process flow of the biosensor fabrication, followed by drawing of the actual chrome mask using the AutoCAD software. The overall width and length of the device is optimized at 16 mm and 16 mm, respectively. Fabrication processes of the biosensor required five chrome masks, which included source and drain formation mask, the back gate area formation mask, electrode formation mask, front gate area formation mask, and passivation area formation mask. The complete chrome masks design will be sent for chrome mask fabrication and for future use in biosensor fabrication.

Understanding the significance variables for fabrication of fish gelatin nanoparticles by Plackett-Burman design

NASA Astrophysics Data System (ADS)

Subara, Deni; Jaswir, Irwandi; Alkhatib, Maan Fahmi Rashid; Noorbatcha, Ibrahim Ali

2018-01-01

The aim of this experiment is to screen and to understand the process variables on the fabrication of fish gelatin nanoparticles by using quality-design approach. The most influencing process variables were screened by using Plackett-Burman design. Mean particles size, size distribution, and zeta potential were found in the range 240±9.76 nm, 0.3, and -9 mV, respectively. Statistical results explained that concentration of acetone, pH of solution during precipitation step and volume of cross linker had a most significant effect on particles size of fish gelatin nanoparticles. It was found that, time and chemical consuming is lower than previous research. This study revealed the potential of quality-by design in understanding the effects of process variables on the fish gelatin nanoparticles production.

Programmable data collection platform study

NASA Technical Reports Server (NTRS)

1976-01-01

The results of a feasibility study incorporating microprocessors in data collection platforms in described. An introduction to microcomputer hardware and software concepts is provided. The influence of microprocessor technology on the design of programmable data collection platform hardware is discussed. A standard modular PDCP design capable of meeting the design goals is proposed, and the process of developing PDCP programs is examined. A description of design and construction of the UT PDCP development system is given.

Bench scale demonstration and conceptual engineering for DETOX{sup SM} catalyzed wet oxidation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Moslander, J.; Bell, R.; Robertson, D.

1994-06-01

Laboratory and bench scale studies of the DETOX{sup SM} catalyzed wet oxidation process have been performed with the object of developing the process for treatment of hazardous and mixed wastes. Reaction orders, apparent rates, and activation energies have been determined for a range of organic waste surrogates. Reaction intermediates and products have been analyzed. Metals` fates have been determined. Bench scale units have been designed, fabricated, and tested with solid and liquid organic waste surrogates. Results from the laboratory and bench scale studies have been used to develop conceptual designs for application of the process to hazardous and mixed wastes.

Solar thermochemical process interface study

NASA Technical Reports Server (NTRS)

1984-01-01

The design and analyses of a subsystem of a hydrogen production process are described. The process is based on solar driven thermochemical reactions. The subject subsystem receives sulfuric acid of 60% concentration at 100 C, 1 atm pressure. The acid is further concentrated, vaporized, and decomposed (at a rate of 122 g moles/sec H2SO4) into SO2, O2, and water. The produce stream is cooled to 100 C. Three subsystem options, each being driven by direct solar energy, were designed and analyzed. The results are compared with a prior study case in which solar energy was provided indirectly through a helium loop.

Virtual HRD and National Culture: An Information Processing Perspective

ERIC Educational Resources Information Center

Chung, Chih-Hung; Angnakoon, Putthachat; Li, Jessica; Allen, Jeff

2016-01-01

Purpose: The purpose of this study is to provide researchers with a better understanding of the cultural impact on information processing in virtual learning environment. Design/methodology/approach: This study uses a causal loop diagram to depict the cultural impact on information processing in the virtual human resource development (VHRD)…

How Instructional Design Experts Use Knowledge and Experience to Solve Ill-Structured Problems

ERIC Educational Resources Information Center

Ertmer, Peggy A.; Stepich, Donald A.; York, Cindy S.; Stickman, Ann; Wu, Xuemei (Lily); Zurek, Stacey; Goktas, Yuksel

2008-01-01

This study examined how instructional design (ID) experts used their prior knowledge and previous experiences to solve an ill-structured instructional design problem. Seven experienced designers used a think-aloud procedure to articulate their problem-solving processes while reading a case narrative. Results, presented in the form of four…

Teachers as Designers: Multimodal Immersion and Strategic Reading on the Internet

ERIC Educational Resources Information Center

Dalton, Bridget; Smith, Blaine E.

2012-01-01

This study examined teachers' literacy and technology integration in their design of Internet-based lessons for Grade 1-6 students using a tool that scaffolds the design process to focus on Internet resources and reading strategies. Twenty-six teachers' lessons on a public database were analyzed for design orientation, goals, curricular…

Establishment of a Digital Knowledge Conversion Architecture Design Learning with High User Acceptance

ERIC Educational Resources Information Center

Wu, Yun-Wu; Weng, Apollo; Weng, Kuo-Hua

2017-01-01

The purpose of this study is to design a knowledge conversion and management digital learning system for architecture design learning, helping students to share, extract, use and create their design knowledge through web-based interactive activities based on socialization, internalization, combination and externalization process in addition to…

Comparing Personal Characteristic Factors of Imagination between Expert and Novice Designers within Different Product Design Stages

ERIC Educational Resources Information Center

Huang, Yinghsiu; Li, Jianyou

2015-01-01

Imagination plays a key role in various domains in helping to create innovative ideas, drawings, poems, movies, products, etc. In product design domain, the personal characteristics of imagination are crucial abilities for conceiving novel ideas during design processes. This study focuses on personal characteristic differences and similarities…

Launch Vehicle Design Process: Characterization, Technical Integration, and Lessons Learned

NASA Technical Reports Server (NTRS)

Blair, J. C.; Ryan, R. S.; Schutzenhofer, L. A.; Humphries, W. R.

2001-01-01

Engineering design is a challenging activity for any product. Since launch vehicles are highly complex and interconnected and have extreme energy densities, their design represents a challenge of the highest order. The purpose of this document is to delineate and clarify the design process associated with the launch vehicle for space flight transportation. The goal is to define and characterize a baseline for the space transportation design process. This baseline can be used as a basis for improving effectiveness and efficiency of the design process. The baseline characterization is achieved via compartmentalization and technical integration of subsystems, design functions, and discipline functions. First, a global design process overview is provided in order to show responsibility, interactions, and connectivity of overall aspects of the design process. Then design essentials are delineated in order to emphasize necessary features of the design process that are sometimes overlooked. Finally the design process characterization is presented. This is accomplished by considering project technical framework, technical integration, process description (technical integration model, subsystem tree, design/discipline planes, decision gates, and tasks), and the design sequence. Also included in the document are a snapshot relating to process improvements, illustrations of the process, a survey of recommendations from experienced practitioners in aerospace, lessons learned, references, and a bibliography.

Design of forging process variables under uncertainties

NASA Astrophysics Data System (ADS)

Repalle, Jalaja; Grandhi, Ramana V.

2005-02-01

Forging is a complex nonlinear process that is vulnerable to various manufacturing anomalies, such as variations in billet geometry, billet/die temperatures, material properties, and workpiece and forging equipment positional errors. A combination of these uncertainties could induce heavy manufacturing losses through premature die failure, final part geometric distortion, and reduced productivity. Identifying, quantifying, and controlling the uncertainties will reduce variability risk in a manufacturing environment, which will minimize the overall production cost. In this article, various uncertainties that affect the forging process are identified, and their cumulative effect on the forging tool life is evaluated. Because the forging process simulation is time-consuming, a response surface model is used to reduce computation time by establishing a relationship between the process performance and the critical process variables. A robust design methodology is developed by incorporating reliability-based optimization techniques to obtain sound forging components. A case study of an automotive-component forging-process design is presented to demonstrate the applicability of the method.

Working on the Boundaries: Philosophies and Practices of the Design Process

NASA Technical Reports Server (NTRS)

Ryan, R.; Blair, J.; Townsend, J.; Verderaime, V.

1996-01-01

While systems engineering process is a program formal management technique and contractually binding, the design process is the informal practice of achieving the design project requirements throughout all design phases of the systems engineering process. The design process and organization are systems and component dependent. Informal reviews include technical information meetings and concurrent engineering sessions, and formal technical discipline reviews are conducted through the systems engineering process. This paper discusses and references major philosophical principles in the design process, identifies its role in interacting systems and disciplines analyses and integrations, and illustrates the process application in experienced aerostructural designs.

The Challenge of Being an Instructional Designer for New Media Development: A View from the Practitioners.

ERIC Educational Resources Information Center

Liu, Min; Gibby, Scott; Quiros, Ondrea; Demps, Elaine

The rapid changes in the field of technology are redefining the process of developing technology-enhanced educational materials as well as the roles of developers involved in the process.The purpose of this study was to learn from practitioners the roles and responsibilities of an instructional designer in developing new media enhanced…

Exploring the Design, Development and Use of Websites through Accessibility and Usability Studies

ERIC Educational Resources Information Center

Foley, Alan

2011-01-01

In this paper, data obtained from a university website accessibility and usability validation process are analyzed and used to demonstrate how the design process can affect the online experience for users with disabilities. Interviews, observations, and use data (e.g. where users clicked on a page or what path taken through a site) were collected.…

New procedures of ergonomics design in a large oil company.

PubMed

Alhadeff, Cynthia Mossé; Silva, Rosana Fernandes da; Reis, Márcia Sales dos

2012-01-01

This study presents the challenge involved in the negotiation and construction of a standard process in a major petroleum company that has the purpose of guiding the implementation of ergonomic studies in the development of projects, systemising the implementation of ergonomics design. The standard was created by a multi-disciplinary working group consisting of specialists in ergonomics, who work in a number of different areas of the company. The objective was to guide "how to" undertake ergonomics in all projects, taking into consideration the development of the ergonomic appraisals of work. It also established that all the process, in each project phase, should be accompanied by a specialist in ergonomics. This process as an innovation in the conception of projects in this company, signals a change of culture, and, for this reason requires broad dissemination throughout the several company leadership levels, and training of professionals in projects of ergonomics design. An implementation plan was also prepared and approved by the corporate governance, complementing the proposed challenge. In this way, this major oil company will implement new procedures of ergonomics design to promote health, safety, and wellbeing of the workforce, besides improving the performance and reliability of its systems and processes.

How Do High School Students Solve Probability Problems? A Mixed Methods Study on Probabilistic Reasoning

ERIC Educational Resources Information Center

Heyvaert, Mieke; Deleye, Maarten; Saenen, Lore; Van Dooren, Wim; Onghena, Patrick

2018-01-01

When studying a complex research phenomenon, a mixed methods design allows to answer a broader set of research questions and to tap into different aspects of this phenomenon, compared to a monomethod design. This paper reports on how a sequential equal status design (QUAN ? QUAL) was used to examine students' reasoning processes when solving…

Are You Ready to Teach Secondary Mathematics in the 21st Century? A Study of Preservice Teachers' Digital Game Design Experience

ERIC Educational Resources Information Center

Li, Qing; Lemieux, Collette; Vandermeiden, Elise; Nathoo, Shahista

2013-01-01

This research study examines preservice teachers' experiences of learning through game design. In particular, we investigate how their perceptions of digital games have evolved through the process of designing and building their own educational games. We are also concerned with the knowledge and reasoning skills that preservice teachers…

Design-Based Research and Video Game Based Learning: Developing the Educational Video Game "Citizen Science"

ERIC Educational Resources Information Center

Gaydos, Matthew J.

2013-01-01

This paper presents a series of studies detailing the research and development of the educational science video game "Citizen Science." It documents the design process, beginning with the initial grant and ending with a case study of two teachers who used the game in their classrooms. Following a design-based research approach, this…

Development and Validation of a Web-Based Module to Teach Metacognitive Learning Strategies to Students in Higher Education

ERIC Educational Resources Information Center

Singh, Oma B.

2009-01-01

This study used a design based-research (DBR) methodology to examine how an Instructional Systematic Design (ISD) process such as ADDIE (Analysis, Design, Development, Implementation, Evaluation) can be employed to develop a web-based module to teach metacognitive learning strategies to students in higher education. The goal of the study was…

The study of human higher mental functions as they relate to neurophysiological processes and personal characteristics

NASA Astrophysics Data System (ADS)

Runnova, Anastasiya; Zhuravlev, Maxim; Kulanin, Roman; Protasov, Pavel; Hramov, Alexander; Koronovskii, Alexey

2018-02-01

In this paper we study the correlation between the neurophysiological processes and personal characteristics arising in the processes of human higher mental functions. We find that the activity of the brain correlates with the results of psychological tests (according to the Cattell test). Experimental studies and math processing are described for operation design with the registration of human multi-channel EEG data in two phases (the processes of passive wakefulness (background) and special psychological testing (active phase)).

3D Printed Surgical Instruments: The Design and Fabrication Process.

PubMed

George, Mitchell; Aroom, Kevin R; Hawes, Harvey G; Gill, Brijesh S; Love, Joseph

2017-01-01

3D printing is an additive manufacturing process allowing the creation of solid objects directly from a digital file. We believe recent advances in additive manufacturing may be applicable to surgical instrument design. This study investigates the feasibility, design and fabrication process of usable 3D printed surgical instruments. The computer-aided design package SolidWorks (Dassault Systemes SolidWorks Corp., Waltham MA) was used to design a surgical set including hemostats, needle driver, scalpel handle, retractors and forceps. These designs were then printed on a selective laser sintering (SLS) Sinterstation HiQ (3D Systems, Rock Hill SC) using DuraForm EX plastic. The final printed products were evaluated by practicing general surgeons for ergonomic functionality and performance, this included simulated surgery and inguinal hernia repairs on human cadavers. Improvements were identified and addressed by adjusting design and build metrics. Repeated manufacturing processes and redesigns led to the creation of multiple functional and fully reproducible surgical sets utilizing the user feedback of surgeons. Iterative cycles including design, production and testing took an average of 3 days. Each surgical set was built using the SLS Sinterstation HiQ with an average build time of 6 h per set. Functional 3D printed surgical instruments are feasible. Advantages compared to traditional manufacturing methods include no increase in cost for increased complexity, accelerated design to production times and surgeon specific modifications.

Development and validation of a building design waste reduction model.

PubMed

Llatas, C; Osmani, M

2016-10-01

Reduction in construction waste is a pressing need in many countries. The design of building elements is considered a pivotal process to achieve waste reduction at source, which enables an informed prediction of their wastage reduction levels. However the lack of quantitative methods linking design strategies to waste reduction hinders designing out waste practice in building projects. Therefore, this paper addresses this knowledge gap through the design and validation of a Building Design Waste Reduction Strategies (Waste ReSt) model that aims to investigate the relationships between design variables and their impact on onsite waste reduction. The Waste ReSt model was validated in a real-world case study involving 20 residential buildings in Spain. The validation process comprises three stages. Firstly, design waste causes were analyzed. Secondly, design strategies were applied leading to several alternative low waste building elements. Finally, their potential source reduction levels were quantified and discussed within the context of the literature. The Waste ReSt model could serve as an instrumental tool to simulate designing out strategies in building projects. The knowledge provided by the model could help project stakeholders to better understand the correlation between the design process and waste sources and subsequently implement design practices for low-waste buildings. Copyright © 2016 Elsevier Ltd. All rights reserved.

Multi-Attribute Tradespace Exploration in Space System Design

NASA Astrophysics Data System (ADS)

Ross, A. M.; Hastings, D. E.

2002-01-01

The complexity inherent in space systems necessarily requires intense expenditures of resources both human and monetary. The high level of ambiguity present in the early design phases of these systems causes long, highly iterative, and costly design cycles. This paper looks at incorporating decision theory methods into the early design processes to streamline communication of wants and needs among stakeholders and between levels of design. Communication channeled through formal utility interviews and analysis enables engineers to better understand the key drivers for the system and allows a more thorough exploration of the design tradespace. Multi-Attribute Tradespace Exploration (MATE), an evolving process incorporating decision theory into model and simulation- based design, has been applied to several space system case studies at MIT. Preliminary results indicate that this process can improve the quality of communication to more quickly resolve project ambiguity, and enable the engineer to discover better value designs for multiple stakeholders. MATE is also being integrated into a concurrent design environment to facilitate the transfer knowledge of important drivers into higher fidelity design phases. Formal utility theory provides a mechanism to bridge the language barrier between experts of different backgrounds and differing needs (e.g. scientists, engineers, managers, etc). MATE with concurrent design couples decision makers more closely to the design, and most importantly, maintains their presence between formal reviews.

Automated Space Processing Payloads Study. Volume 1: Executive Summary

NASA Technical Reports Server (NTRS)

1975-01-01

An investigation is described which examined the extent to which the experiment hardware and operational requirements can be met by automatic control and material handling devices; payload and system concepts are defined which make extensive use of automation technology. Topics covered include experiment requirements and hardware data, capabilities and characteristics of industrial automation equipment and controls, payload grouping, automated payload conceptual design, space processing payload preliminary design, automated space processing payloads for early shuttle missions, and cost and scheduling.

CisLunar Habitat Internal Architecture Design Criteria

NASA Technical Reports Server (NTRS)

Jones, R.; Kennedy, K.; Howard, R.; Whitmore, M.; Martin, C.; Garate, J.

2017-01-01

BACKGROUND: In preparation for human exploration to Mars, there is a need to define the development and test program that will validate deep space operations and systems. In that context, a Proving Grounds CisLunar habitat spacecraft is being defined as the next step towards this goal. This spacecraft will operate differently from the ISS or other spacecraft in human history. The performance envelope of this spacecraft (mass, volume, power, specifications, etc.) is being defined by the Future Capabilities Study Team. This team has recognized the need for a human-centered approach for the internal architecture of this spacecraft and has commissioned a CisLunar Phase-1 Habitat Internal Architecture Study Team to develop a NASA reference configuration, providing the Agency with a "smart buyer" approach for future acquisition. THE CISLUNAR HABITAT INTERNAL ARCHITECTURE STUDY: Overall, the CisLunar Habitat Internal Architecture study will address the most significant questions and risks in the current CisLunar architecture, habitation, and operations concept development. This effort is achieved through definition of design criteria, evaluation criteria and process, design of the CisLunar Habitat Phase-1 internal architecture, and the development and fabrication of internal architecture concepts combined with rigorous and methodical Human-in-the-Loop (HITL) evaluations and testing of the conceptual innovations in a controlled test environment. The vision of the CisLunar Habitat Internal Architecture Study is to design, build, and test a CisLunar Phase-1 Habitat Internal Architecture that will be used for habitation (e.g. habitability and human factors) evaluations. The evaluations will mature CisLunar habitat evaluation tools, guidelines, and standards, and will interface with other projects such as the Advanced Exploration Systems (AES) Program integrated Power, Avionics, Software (iPAS), and Logistics for integrated human-in-the-loop testing. The mission of the CisLunar Habitat Internal Architecture Study is to become a forcing function to establish a common understanding of CisLunar Phase-1 Habitation Internal Architecture design criteria, processes, and tools. The scope of the CisLunar Habitat Internal Architecture study is to design, develop, demonstrate, and evaluate a Phase-1 CisLunar Habitat common module internal architecture based on design criteria agreed to by NASA, the International Partners, and Commercial Exploration teams. This task is to define the CisLunar Phase-1 Internal Architecture Government Reference Design, assist NASA in becoming a "smart buyer" for Phase-1 Habitat Concepts, and ultimately to derive standards and requirements from the Internal Architecture Design Process. The first step was to define a Habitat Internal Architecture Design Criteria and create a structured philosophy to be used by design teams as a filter by which critical aspects of consideration would be identified for the purpose of organizing and utilizing interior spaces. With design criteria in place, the team will develop a series of iterative internal architecture concept designs which will be assessed by means of an evaluation criteria and process. These assessments will successively drive and refine the design, leading to the combination and down-selection of design concepts. A single refined reference design configuration will be developed into in a medium-to-high fidelity mockup. A multi-day human-in-the-loop mission test will fully evaluate the reference design and validate its configuration. Lessons learned from the design and evaluation will enable the team to identify appropriate standards for Phase-1 CisLunar Habitat Internal Architecture and will enable NASA to develop derived requirements in support of maturing CisLunar Habitation capabilities. This paper will describe the criteria definition process, workshop event, and resulting CisLunar Phase-1 Habitat Internal Architecture Design Criteria.

Earthdata Search Client: Usability Review Process, Results, and Implemented Changes, Using Earthdata Search Client as a Case Study

NASA Technical Reports Server (NTRS)

Siarto, Jeff; Reese, Mark; Shum, Dana; Baynes, Katie

2016-01-01

User experience and visual design are greatly improved when usability testing is performed on a periodic basis. Design decisions should be tested by real users so that application owners can understand the effectiveness of each decision and identify areas for improvement. It is important that applications be tested not just once, but as a part of a continuing process that looks to build upon previous tests. NASA's Earthdata Search Client has undergone a usability study to ensure its users' needs are being met and that users understand how to use the tool efficiently and effectively. This poster will highlight the process followed for usability study, the results of the study, and what has been implemented in light of the results to improve the application's interface.

Safeguards Approaches for Black Box Processes or Facilities

DOE Office of Scientific and Technical Information (OSTI.GOV)

Diaz-Marcano, Helly; Gitau, Ernest TN; Hockert, John

2013-09-25

The objective of this study is to determine whether a safeguards approach can be developed for “black box” processes or facilities. These are facilities where a State or operator may limit IAEA access to specific processes or portions of a facility; in other cases, the IAEA may be prohibited access to the entire facility. The determination of whether a black box process or facility is safeguardable is dependent upon the details of the process type, design, and layout; the specific limitations on inspector access; and the restrictions placed upon the design information that can be provided to the IAEA. Thismore » analysis identified the necessary conditions for safeguardability of black box processes and facilities.« less

Analysis of Work Design in Rubber Processing Plant

NASA Astrophysics Data System (ADS)

Wahyuni, Dini; Nasution, Harmein; Budiman, Irwan; Wijaya, Khairini

2018-02-01

The work design illustrates how structured jobs, tasks, and roles are defined and modified and their impact on individuals, groups, and organizations. If the work is not designed well, the company must pay greater costs for workers' health, longer production processes or even penalties for not being able to meet the delivery schedule. This is visible to the condition in a rubber processing factory in North Sumatra. Work design aspects such as layouts, machinery and equipment, worker's physical working environment, work methods, and organizational policies have not been well-organized. Coagulum grinding machines into sheets are often damaged, resulting in 4 times the delay of product delivery in 2016, the presence of complaints of heat exposure submitted by workers, and workstation that has not been properly arranged is an indication of the need for work design. The research data will be collected through field observation, and distribution of questionnaires related aspects of work design. The result of the analysis depends on the respondent's answer from the distributed questionnaire regarding the 6 aspects studied.

Influence of operating conditions on the optimum design of electric vehicle battery cooling plates

NASA Astrophysics Data System (ADS)

Jarrett, Anthony; Kim, Il Yong

2014-01-01

The efficiency of cooling plates for electric vehicle batteries can be improved by optimizing the geometry of internal fluid channels. In practical operation, a cooling plate is exposed to a range of operating conditions dictated by the battery, environment, and driving behaviour. To formulate an efficient cooling plate design process, the optimum design sensitivity with respect to each boundary condition is desired. This determines which operating conditions must be represented in the design process, and therefore the complexity of designing for multiple operating conditions. The objective of this study is to determine the influence of different operating conditions on the optimum cooling plate design. Three important performance measures were considered: temperature uniformity, mean temperature, and pressure drop. It was found that of these three, temperature uniformity was most sensitive to the operating conditions, especially with respect to the distribution of the input heat flux, and also to the coolant flow rate. An additional focus of the study was the distribution of heat generated by the battery cell: while it is easier to assume that heat is generated uniformly, by using an accurate distribution for design optimization, this study found that cooling plate performance could be significantly improved.

Evaluating hospital design from an operations management perspective.

PubMed

Vos, Leti; Groothuis, Siebren; van Merode, Godefridus G

2007-12-01

This paper describes an evaluation method for the assessment of hospital building design from the viewpoint of operations management to assure that the building design supports the efficient and effective operating of care processes now and in the future. The different steps of the method are illustrated by a case study. In the case study an experimental design is applied to assess the effect of used logistical concepts, patient mix and technologies. The study shows that the evaluation method provides a valuable tool for the assessment of both functionality and the ability to meet future developments in operational control of a building design.

Thermodynamic Studies for Drug Design and Screening

PubMed Central

Garbett, Nichola C.; Chaires, Jonathan B.

2012-01-01

Introduction A key part of drug design and development is the optimization of molecular interactions between an engineered drug candidate and its binding target. Thermodynamic characterization provides information about the balance of energetic forces driving binding interactions and is essential for understanding and optimizing molecular interactions. Areas covered This review discusses the information that can be obtained from thermodynamic measurements and how this can be applied to the drug development process. Current approaches for the measurement and optimization of thermodynamic parameters are presented, specifically higher throughput and calorimetric methods. Relevant literature for this review was identified in part by bibliographic searches for the period 2004 – 2011 using the Science Citation Index and PUBMED and the keywords listed below. Expert opinion The most effective drug design and development platform comes from an integrated process utilizing all available information from structural, thermodynamic and biological studies. Continuing evolution in our understanding of the energetic basis of molecular interactions and advances in thermodynamic methods for widespread application are essential to realize the goal of thermodynamically-driven drug design. Comprehensive thermodynamic evaluation is vital early in the drug development process to speed drug development towards an optimal energetic interaction profile while retaining good pharmacological properties. Practical thermodynamic approaches, such as enthalpic optimization, thermodynamic optimization plots and the enthalpic efficiency index, have now matured to provide proven utility in design process. Improved throughput in calorimetric methods remains essential for even greater integration of thermodynamics into drug design. PMID:22458502

Field guide for collecting and processing stream-water samples for the National Water-Quality Assessment Program

USGS Publications Warehouse

Shelton, Larry R.

1994-01-01

The U.S. Geological Survey's National Water-Quality Assessment program includes extensive data- collection efforts to assess the quality of the Nations's streams. These studies require analyses of stream samples for major ions, nutrients, sediments, and organic contaminants. For the information to be comparable among studies in different parts of the Nation, consistent procedures specifically designed to produce uncontaminated samples for trace analysis in the laboratory are critical. This field guide describes the standard procedures for collecting and processing samples for major ions, nutrients, organic contaminants, sediment, and field analyses of conductivity, pH, alkalinity, and dissolved oxygen. Samples are collected and processed using modified and newly designed equipment made of Teflon to avoid contamination, including nonmetallic samplers (D-77 and DH-81) and a Teflon sample splitter. Field solid-phase extraction procedures developed to process samples for organic constituent analyses produce an extracted sample with stabilized compounds for more accurate results. Improvements to standard operational procedures include the use of processing chambers and capsule filtering systems. A modified collecting and processing procedure for organic carbon is designed to avoid contamination from equipment cleaned with methanol. Quality assurance is maintained by strict collecting and processing procedures, replicate sampling, equipment blank samples, and a rigid cleaning procedure using detergent, hydrochloric acid, and methanol.

Conducting pilot and feasibility studies.

PubMed

Cope, Diane G

2015-03-01

Planning a well-designed research study can be tedious and laborious work. However, this process is critical and ultimately can produce valid, reliable study findings. Designing a large-scale randomized, controlled trial (RCT)-the gold standard in quantitative research-can be even more challenging. Even the most well-planned study potentially can result in issues with research procedures and design, such as recruitment, retention, or methodology. One strategy that may facilitate sound study design is the completion of a pilot or feasibility study prior to the initiation of a larger-scale trial. This article will discuss pilot and feasibility studies, their advantages and disadvantages, and implications for oncology nursing research. 
.

Study of a dry room in a battery manufacturing plant using a process model

NASA Astrophysics Data System (ADS)

Ahmed, Shabbir; Nelson, Paul A.; Dees, Dennis W.

2016-09-01

The manufacture of lithium ion batteries requires some processing steps to be carried out in a dry room, where the moisture content should remain below 100 parts per million. The design and operation of such a dry room adds to the cost of the battery. This paper studied the humidity management of the air to and from the dry room to understand the impact of design and operating parameters on the energy demand and the cost contribution towards the battery manufacturing cost. The study was conducted with the help of a process model for a dry room with a volume of 16,000 cubic meters. For a defined base case scenario it was found that the dry room operation has an energy demand of approximately 400 kW. The paper explores some tradeoffs in design and operating parameters by looking at the humidity reduction by quenching the make-up air vs. at the desiccant wheel, and the impact of the heat recovery from the desiccant regeneration cycle.

Simulation Of Assembly Processes With Technical Of Virtual Reality

NASA Astrophysics Data System (ADS)

García García, Manuel; Arenas Reina, José Manuel; Lite, Alberto Sánchez; Sebastián Pérez, Miguel Ángel

2009-11-01

Virtual reality techniques use at industrial processes provides a real approach to product life cycle. For components manual assembly, the use of virtual surroundings facilitates a simultaneous engineering in which variables such as human factors and productivity take a real act. On the other hand, in the actual phase of industrial competition it is required a rapid adjustment to client needs and to market situation. In this work it is analyzed the assembly of the front components of a vehicle using virtual reality tools and following up a product-process design methodology which includes every life service stage. This study is based on workstations design, taking into account productive and human factors from the ergonomic point of view implementing a postural study of every assembly operation, leaving the rest of stages for a later study. Design is optimized applying this methodology together with the use of virtual reality tools. It is also achieved a 15% reduction on time assembly and of 90% reduction in muscle—skeletal diseases at every assembly operation.

A Conceptual Aerospace Vehicle Structural System Modeling, Analysis and Design Process

NASA Technical Reports Server (NTRS)

Mukhopadhyay, Vivek

2007-01-01

A process for aerospace structural concept analysis and design is presented, with examples of a blended-wing-body fuselage, a multi-bubble fuselage concept, a notional crew exploration vehicle, and a high altitude long endurance aircraft. Aerospace vehicle structures must withstand all anticipated mission loads, yet must be designed to have optimal structural weight with the required safety margins. For a viable systems study of advanced concepts, these conflicting requirements must be imposed and analyzed early in the conceptual design cycle, preferably with a high degree of fidelity. In this design process, integrated multidisciplinary analysis tools are used in a collaborative engineering environment. First, parametric solid and surface models including the internal structural layout are developed for detailed finite element analyses. Multiple design scenarios are generated for analyzing several structural configurations and material alternatives. The structural stress, deflection, strain, and margins of safety distributions are visualized and the design is improved. Over several design cycles, the refined vehicle parts and assembly models are generated. The accumulated design data is used for the structural mass comparison and concept ranking. The present application focus on the blended-wing-body vehicle structure and advanced composite material are also discussed.

Gasoline from coal in the state of Illinois: feasibility study. Volume I. Design. [KBW gasification process, ICI low-pressure methanol process and Mobil M-gasoline process

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1980-01-01

Volume 1 describes the proposed plant: KBW gasification process, ICI low-pressure methanol process and Mobil M-gasoline process, and also with ancillary processes, such as oxygen plant, shift process, RECTISOL purification process, sulfur recovery equipment and pollution control equipment. Numerous engineering diagrams are included. (LTN)

An Intelligent Automation Platform for Rapid Bioprocess Design.

PubMed

Wu, Tianyi; Zhou, Yuhong

2014-08-01

Bioprocess development is very labor intensive, requiring many experiments to characterize each unit operation in the process sequence to achieve product safety and process efficiency. Recent advances in microscale biochemical engineering have led to automated experimentation. A process design workflow is implemented sequentially in which (1) a liquid-handling system performs high-throughput wet lab experiments, (2) standalone analysis devices detect the data, and (3) specific software is used for data analysis and experiment design given the user's inputs. We report an intelligent automation platform that integrates these three activities to enhance the efficiency of such a workflow. A multiagent intelligent architecture has been developed incorporating agent communication to perform the tasks automatically. The key contribution of this work is the automation of data analysis and experiment design and also the ability to generate scripts to run the experiments automatically, allowing the elimination of human involvement. A first-generation prototype has been established and demonstrated through lysozyme precipitation process design. All procedures in the case study have been fully automated through an intelligent automation platform. The realization of automated data analysis and experiment design, and automated script programming for experimental procedures has the potential to increase lab productivity. © 2013 Society for Laboratory Automation and Screening.

An Intelligent Automation Platform for Rapid Bioprocess Design

PubMed Central

Wu, Tianyi

2014-01-01

Bioprocess development is very labor intensive, requiring many experiments to characterize each unit operation in the process sequence to achieve product safety and process efficiency. Recent advances in microscale biochemical engineering have led to automated experimentation. A process design workflow is implemented sequentially in which (1) a liquid-handling system performs high-throughput wet lab experiments, (2) standalone analysis devices detect the data, and (3) specific software is used for data analysis and experiment design given the user’s inputs. We report an intelligent automation platform that integrates these three activities to enhance the efficiency of such a workflow. A multiagent intelligent architecture has been developed incorporating agent communication to perform the tasks automatically. The key contribution of this work is the automation of data analysis and experiment design and also the ability to generate scripts to run the experiments automatically, allowing the elimination of human involvement. A first-generation prototype has been established and demonstrated through lysozyme precipitation process design. All procedures in the case study have been fully automated through an intelligent automation platform. The realization of automated data analysis and experiment design, and automated script programming for experimental procedures has the potential to increase lab productivity. PMID:24088579

The effect of requirements prioritization on avionics system conceptual design

NASA Astrophysics Data System (ADS)

Lorentz, John

This dissertation will provide a detailed approach and analysis of a new collaborative requirements prioritization methodology that has been used successfully on four Coast Guard avionics acquisition and development programs valued at $400M+. A statistical representation of participant study results will be discussed and analyzed in detail. Many technically compliant projects fail to deliver levels of performance and capability that the customer desires. Some of these systems completely meet "threshold" levels of performance; however, the distribution of resources in the process devoted to the development and management of the requirements does not always represent the voice of the customer. This is especially true for technically complex projects such as modern avionics systems. A simplified facilitated process for prioritization of system requirements will be described. The collaborative prioritization process, and resulting artifacts, aids the systems engineer during early conceptual design. All requirements are not the same in terms of customer priority. While there is a tendency to have many thresholds inside of a system design, there is usually a subset of requirements and system performance that is of the utmost importance to the design. These critical capabilities and critical levels of performance typically represent the reason the system is being built. The systems engineer needs processes to identify these critical capabilities, the associated desired levels of performance, and the risks associated with the specific requirements that define the critical capability. The facilitated prioritization exercise is designed to collaboratively draw out these critical capabilities and levels of performance so they can be emphasized in system design. Developing the purpose, scheduling and process for prioritization events are key elements of systems engineering and modern project management. The benefits of early collaborative prioritization flow throughout the project schedule, resulting in greater success during system deployment and operational testing. This dissertation will discuss the data and findings from participant studies, present a literature review of systems engineering and design processes, and test the hypothesis that the prioritization process had no effect on stakeholder sentiment related to the conceptual design. In addition, the "Requirements Rationalization" process will be discussed in detail. Avionics, like many other systems, has transitioned from a discrete electronics engineering, hard engineering discipline to incorporate software engineering as a core process of the technology development cycle. As with other software-based systems, avionics now has significant soft system attributes that must be considered in the design process. The boundless opportunities that exist in software design demand prioritization to focus effort onto the critical functions that the software must provide. This has been a well documented and understood phenomenon in the software development community for many years. This dissertation will attempt to link the effect of software integrated avionics to the benefits of prioritization of requirements in the problem space and demonstrate the sociological and technical benefits of early prioritization practices.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Xu, Hongyi; Li, Yang; Zeng, Danielle

Process integration and optimization is the key enabler of the Integrated Computational Materials Engineering (ICME) of carbon fiber composites. In this paper, automated workflows are developed for two types of composites: Sheet Molding Compounds (SMC) short fiber composites, and multi-layer unidirectional (UD) composites. For SMC, the proposed workflow integrates material processing simulation, microstructure representation volume element (RVE) models, material property prediction and structure preformation simulation to enable multiscale, multidisciplinary analysis and design. Processing parameters, microstructure parameters and vehicle subframe geometry parameters are defined as the design variables; the stiffness and weight of the structure are defined as the responses. Formore » multi-layer UD structure, this work focuses on the discussion of different design representation methods and their impacts on the optimization performance. Challenges in ICME process integration and optimization are also summarized and highlighted. Two case studies are conducted to demonstrate the integrated process and its application in optimization.« less

Software for biomedical engineering signal processing laboratory experiments.

PubMed

Tompkins, Willis J; Wilson, J

2009-01-01

In the early 1990's we developed a special computer program called UW DigiScope to provide a mechanism for anyone interested in biomedical digital signal processing to study the field without requiring any other instrument except a personal computer. There are many digital filtering and pattern recognition algorithms used in processing biomedical signals. In general, students have very limited opportunity to have hands-on access to the mechanisms of digital signal processing. In a typical course, the filters are designed non-interactively, which does not provide the student with significant understanding of the design constraints of such filters nor their actual performance characteristics. UW DigiScope 3.0 is the first major update since version 2.0 was released in 1994. This paper provides details on how the new version based on MATLAB! works with signals, including the filter design tool that is the programming interface between UW DigiScope and processing algorithms.

A design process for using normative models in shared decision making: a case study in the context of prenatal testing.

PubMed

Rapaport, Sivan; Leshno, Moshe; Fink, Lior

2014-12-01

Shared decision making (SDM) encourages the patient to play a more active role in the process of medical consultation and its primary objective is to find the best treatment for a specific patient. Recent findings, however, show that patient preferences cannot be easily or accurately judged on the basis of communicative exchange during routine office visits, even for patients who seek to expand their role in medical decision making (MDM). The objective of this study is to improve the quality of patient-physician communication by developing a novel design process for SDM and then demonstrating, through a case study, the applicability of this process in enabling the use of a normative model for a specific medical situation. Our design process goes through the following stages: definition of medical situation and decision problem, development/identification of normative model, adaptation of normative model, empirical analysis and development of decision support systems (DSS) tools that facilitate the SDM process in the specific medical situation. This study demonstrates the applicability of the process through the implementation of the general normative theory of MDM under uncertainty for the medical-financial dilemma of choosing a physician to perform amniocentesis. The use of normative models in SDM raises several issues, such as the goal of the normative model, the relation between the goals of prediction and recommendation, and the general question of whether it is valid to use a normative model for people who do not behave according to the model's assumptions. © 2012 John Wiley & Sons Ltd.

Aircraft Alerting Systems Standardization Study. Phase IV. Accident Implications on Systems Design.

DTIC Science & Technology

1982-06-01

computing and processing to assimilate and process status informa- 5 tion using...provided with capabilities in computing and processing , sensing, interfacing, and controlling and displaying. 17 o Computing and Processing - Algorithms...alerting system to perform a flight status monitor function would require additional sensinq, computing and processing , interfacing, and controlling

Optimisation of process parameters on thin shell part using response surface methodology (RSM)

NASA Astrophysics Data System (ADS)

Faiz, J. M.; Shayfull, Z.; Nasir, S. M.; Fathullah, M.; Rashidi, M. M.

2017-09-01

This study is carried out to focus on optimisation of process parameters by simulation using Autodesk Moldflow Insight (AMI) software. The process parameters are taken as the input in order to analyse the warpage value which is the output in this study. There are some significant parameters that have been used which are melt temperature, mould temperature, packing pressure, and cooling time. A plastic part made of Polypropylene (PP) has been selected as the study part. Optimisation of process parameters is applied in Design Expert software with the aim to minimise the obtained warpage value. Response Surface Methodology (RSM) has been applied in this study together with Analysis of Variance (ANOVA) in order to investigate the interactions between parameters that are significant to the warpage value. Thus, the optimised warpage value can be obtained using the model designed using RSM due to its minimum error value. This study comes out with the warpage value improved by using RSM.

Rethinking Process through Design

ERIC Educational Resources Information Center

Newcomb, Matthew; Leshowitz, Allison

2017-01-01

We take a look at work on writing processes by examining design processes. Design processes offer a greater emphasis on empathy with users, feedback and critique during idea generation, and varied uses of materials. After considering work already done on design and composition, we explore a variety of design processes and develop our own…

Educational Website Design Process: Changes in TPACK Competencies and Experiences

ERIC Educational Resources Information Center

Önal, Nezih; Alemdag, Ecenaz

2018-01-01

The number of technological pedagogical and content knowledge (TPACK) studies has been increasing day by day; however, limited number of studies has provided both quantitative and qualitative findings based on teachers' learning by design experiences. This study aimed to reveal the changes in pre-service teachers' TPACK competencies in the…

Enroute flight planning: The design of cooperative planning systems

NASA Technical Reports Server (NTRS)

Smith, Philip J.; Layton, Chuck; Mccoy, Elaine

1990-01-01

Design concepts and principles to guide in the building of cooperative problem solving systems are being developed and evaluated. In particular, the design of cooperative systems for enroute flight planning is being studied. The investigation involves a three stage process, modeling human performance in existing environments, building cognitive artifacts, and studying the performance of people working in collaboration with these artifacts. The most significant design concepts and principles identified thus far are the principle focus.

Solving a layout design problem by analytic hierarchy process (AHP) and data envelopment analysis (DEA) approach

NASA Astrophysics Data System (ADS)

Tuzkaya, Umut R.; Eser, Arzum; Argon, Goner

2004-02-01

Today, growing amounts of waste due to fast consumption rate of products started an irreversible environmental pollution and damage. A considerable part of this waste is caused by packaging material. With the realization of this fact, various waste policies have taken important steps. Here we considered a firm, where waste Aluminum constitutes majority of raw materials for this fir0m. In order to achieve a profitable recycling process, plant layout should be well designed. In this study, we propose a two-step approach involving Analytic Hierarchy Process (AHP) and Data Envelopment Analysis (DEA) to solve facility layout design problems. A case example is considered to demonstrate the results achieved.

Optimization applications in aircraft engine design and test

NASA Technical Reports Server (NTRS)

Pratt, T. K.

1984-01-01

Starting with the NASA-sponsored STAEBL program, optimization methods based primarily upon the versatile program COPES/CONMIN were introduced over the past few years to a broad spectrum of engineering problems in structural optimization, engine design, engine test, and more recently, manufacturing processes. By automating design and testing processes, many repetitive and costly trade-off studies have been replaced by optimization procedures. Rather than taking engineers and designers out of the loop, optimization has, in fact, put them more in control by providing sophisticated search techniques. The ultimate decision whether to accept or reject an optimal feasible design still rests with the analyst. Feedback obtained from this decision process has been invaluable since it can be incorporated into the optimization procedure to make it more intelligent. On several occasions, optimization procedures have produced novel designs, such as the nonsymmetric placement of rotor case stiffener rings, not anticipated by engineering designers. In another case, a particularly difficult resonance contraint could not be satisfied using hand iterations for a compressor blade, when the STAEBL program was applied to the problem, a feasible solution was obtained in just two iterations.

Students’ Algebraic Thinking Process in Context of Point and Line Properties

NASA Astrophysics Data System (ADS)

Nurrahmi, H.; Suryadi, D.; Fatimah, S.

2017-09-01

Learning of schools algebra is limited to symbols and operating procedures, so students are able to work on problems that only require the ability to operate symbols but unable to generalize a pattern as one of part of algebraic thinking. The purpose of this study is to create a didactic design that facilitates students to do algebraic thinking process through the generalization of patterns, especially in the context of the property of point and line. This study used qualitative method and includes Didactical Design Research (DDR). The result is students are able to make factual, contextual, and symbolic generalization. This happen because the generalization arises based on facts on local terms, then the generalization produced an algebraic formula that was described in the context and perspective of each student. After that, the formula uses the algebraic letter symbol from the symbol t hat uses the students’ language. It can be concluded that the design has facilitated students to do algebraic thinking process through the generalization of patterns, especially in the context of property of the point and line. The impact of this study is this design can use as one of material teaching alternative in learning of school algebra.

Thermal properties of simulated Hanford waste glasses

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rodriguez, Carmen P.; Chun, Jaehun; Crum, Jarrod V.

The Hanford Tank Waste Treatment and Immobilization Plant (WTP) will vitrify the mixed hazardous wastes generated from 45 years of plutonium production. The molten glasses will be poured into stainless steel containers or canisters and subsequently quenched for storage and disposal. Such highly energy-consuming processes require precise thermal properties of materials for appropriate facility design and operations. Key thermal properties (heat capacity, thermal diffusivity, and thermal conductivity) of representative high-level and low-activity waste glasses were studied as functions of temperature in the range of 200 to 800°C (relevant to the cooling process), implementing simultaneous differential scanning calorimetry-thermal gravimetry (DSC-TGA), Xe-flashmore » diffusivity, pycnometry, and dilatometry. The study showed that simultaneous DSC-TGA would be a reliable method to obtain heat capacity of various glasses at the temperature of interest. Accurate thermal properties from this study were shown to provide a more realistic guideline for capacity and time constraint of heat removal process, in comparison to the design basis conservative engineering estimates. The estimates, though useful for design in the absence measured physical properties, can now be supplanted and the measured thermal properties can be used in design verification activities.« less

Reducing construction waste: A study of urban infrastructure projects.

PubMed

de Magalhães, Ruane Fernandes; Danilevicz, Ângela de Moura Ferreira; Saurin, Tarcisio Abreu

2017-09-01

The construction industry is well-known for producing waste detrimental to the environment, and its impacts have increased with the development process of cities. Although there are several studies focused on the environmental impact of residential and commercial buildings, less knowledge is available regarding decreasing construction waste (CW) generation in urban infrastructure projects. This study presents best practices to reduce waste in the said projects, stressing the role of decision-making in the design stage and the effective management of construction processes in public sector. The best practices were identified from literature review, document analysis in 14 projects of urban infrastructure, and both qualitative and quantitative survey with 18 experts (architects and engineers) playing different roles on those projects. The contributions of these research are: (i) the identification of the main building techniques related to the urban design typologies analyzed; (ii) the identification of cause-effect relationships between the design choices and the CW generation diagnosis; (iii) the proposal of a checklist to support the decision-making process, that can be used as a control and evaluation instrument when developing urban infrastructure designs, focused on the construction waste minimization (CWM). Copyright © 2017 Elsevier Ltd. All rights reserved.

Preliminary Study on GF/Carbon/Epoxy Composite Permeability in Designing Close Compartment Processing

NASA Astrophysics Data System (ADS)

Ya’acob, A. M.; Razali, D. A.; Anwar, U. A.; Radhi, A. H.; Ishak, A. A.; Minhat, M.; Aris, K. D. Mohd; Johari, M. K.; Casey, T.

2018-05-01

This project involves discovering how the permeability effect inside a close compartment in processing. After the appropriate pressure range was found, the close compartment was designed by studying the relationship between pressure output and the flow rate. A variety of pressure ranges have been used in this test to determine the effective pressure range that can be applied to the manufacturing process. Based on the results, the suitable pressure ranges were found between 55 psi to 75 psi. These pressures have been chosen based on the area covered on the product surfaces and time taken to penetrate the proposed area. The relationship between pressure and flow rate have been found to be directly proportional until 75 psi only. In conclusion, 70 psi for the proposed design of close compartment mould is suitable to be used to fulfill the required area of 120 mm square within 90 seconds.

Macroergonomic study of food sector company distribution centres.

PubMed

García Acosta, Gabriel; Lange Morales, Karen

2008-07-01

This study focussed on the work system design to be used by a Colombian food sector company for distributing products. It considered the concept of participative ergonomics, where people from the commercial, logistics, operation, occupational health areas worked in conjunction with the industrial designers, ergonomists who methodologically led the project. As a whole, the project was conceived as having five phases: outline, diagnosis, modelling the process, scalability, instrumentation. The results of the project translate into procedures for selecting, projecting a new distribution centre, the operational process model, a description of ergonomic systems that will enable specific work stations to be designed, the procedure for adapting existing warehouses. Strategically, this work helped optimise the company's processes and ensure that knowledge would be transferred within it. In turn, it became a primary prevention strategy in the field of health, aimed at reducing occupational risks, improving the quality of life at work.

Fundamental phenomena on fuel decomposition and boundary layer combustion processes with applications to hybrid rocket motors

NASA Technical Reports Server (NTRS)

Kuo, Kenneth K.; Lu, Y. C.; Chiaverini, Martin J.; Harting, George C.

1994-01-01

An experimental study on the fundamental processes involved in fuel decomposition and boundary layer combustion in hybrid rocket motors is being conducted at the High Pressure Combustion Laboratory of the Pennsylvania State University. This research should provide a useful engineering technology base in the development of hybrid rocket motors as well as a fundamental understanding of the complex processes involved in hybrid propulsion. A high pressure slab motor has been designed and manufactured for conducting experimental investigations. Oxidizer (LOX or GOX) supply and control systems have been designed and partly constructed for the head-end injection into the test chamber. Experiments using HTPB fuel, as well as fuels supplied by NASA designated industrial companies will be conducted. Design and construction of fuel casting molds and sample holders have been completed. The portion of these items for industrial company fuel casting will be sent to the McDonnell Douglas Aerospace Corporation in the near future. The study focuses on the following areas: observation of solid fuel burning processes with LOX or GOX, measurement and correlation of solid fuel regression rate with operating conditions, measurement of flame temperature and radical species concentrations, determination of the solid fuel subsurface temperature profile, and utilization of experimental data for validation of a companion theoretical study (Part 2) also being conducted at PSU.

Development and evaluation of paclitaxel nanoparticles using a quality-by-design approach.

PubMed

Yerlikaya, Firat; Ozgen, Aysegul; Vural, Imran; Guven, Olgun; Karaagaoglu, Ergun; Khan, Mansoor A; Capan, Yilmaz

2013-10-01

The aims of this study were to develop and characterize paclitaxel nanoparticles, to identify and control critical sources of variability in the process, and to understand the impact of formulation and process parameters on the critical quality attributes (CQAs) using a quality-by-design (QbD) approach. For this, a risk assessment study was performed with various formulation and process parameters to determine their impact on CQAs of nanoparticles, which were determined to be average particle size, zeta potential, and encapsulation efficiency. Potential risk factors were identified using an Ishikawa diagram and screened by Plackett-Burman design and finally nanoparticles were optimized using Box-Behnken design. The optimized formulation was further characterized by Fourier transform infrared spectroscopy, X-ray diffractometry, differential scanning calorimetry, scanning electron microscopy, atomic force microscopy, and gas chromatography. It was observed that paclitaxel transformed from crystalline state to amorphous state while totally encapsulating into the nanoparticles. The nanoparticles were spherical, smooth, and homogenous with no dichloromethane residue. In vitro cytotoxicity test showed that the developed nanoparticles are more efficient than free paclitaxel in terms of antitumor activity (more than 25%). In conclusion, this study demonstrated that understanding formulation and process parameters with the philosophy of QbD is useful for the optimization of complex drug delivery systems. © 2013 Wiley Periodicals, Inc. and the American Pharmacists Association.

Construction and Validation of a Questionnaire to Study Future Teachers' Beliefs about Cultural Diversity

ERIC Educational Resources Information Center

López López, M. Carmen; Hinojosa Pareja, Eva F.

2016-01-01

The article presents the construction and validation process of a questionnaire designed to study student teachers' beliefs about cultural diversity. The study, beyond highlighting the complexity involved in the study of beliefs, emphasises their relevance in implementing inclusive educational processes that guarantee the right to a good education…

Design Heuristics in Academic, Corporate, and Military Instruction: More Similar than Different

ERIC Educational Resources Information Center

York, Cindy S.; Ertmer, Peggy A.

2013-01-01

Despite the fact that the practice of instructional design (ID) began in the U. S. military (Branson et al., 1975; Jeffrey & Bratton-Jeffrey, 2004; Reiser, 2102), there is little known regarding which design and development heuristics military instructional designers deem important to the ID process. The study reported in this article was…

User-Centered Design and Usability Testing of a Web Site: An Illustrative Case Study.

ERIC Educational Resources Information Center

Corry, Michael D.; Frick, Theodore W.; Hansen, Lisa

1997-01-01

Presents an overview of user-centered design and usability testing. Describes a Web site evaluation project at a university, the iterative process of rapid prototyping and usability testing, and how the findings helped to improve the design. Discusses recommendations for university Web site design and reflects on problems faced in usability…

Recovering Lost Histories of Educational Design: A Case Study in Contemporary Participatory Strategies

ERIC Educational Resources Information Center

Burke, Catherine; Könings, Karen D.

2016-01-01

Past practices shape and limit the design imagination of teachers, pupils, parents, governors, and others concerned with designing modern schools. Bringing histories of education to the table in the participatory design process of new school buildings and curricula is necessary. Schools having an extraordinary past have the potential to draw from…

Talking to Texts and Sketches: The Function of Written and Graphic Mediation in Engineering Design.

ERIC Educational Resources Information Center

Lewis, Barbara

2000-01-01

Describes the author's research that explores the role of language, particularly texts, in the engineering design process. Notes that results of this case study support a new "mediated" model of engineering design as an inventional activity in which designers use talk, written language, and other symbolic representations as tools to think about…

Advancing Integrated STEM Learning through Engineering Design: Sixth-Grade Students' Design and Construction of Earthquake Resistant Buildings

ERIC Educational Resources Information Center

English, Lyn D.; King, Donna; Smeed, Joanna

2017-01-01

As part of a 3-year longitudinal study, 136 sixth-grade students completed an engineering-based problem on earthquakes involving integrated STEM learning. Students employed engineering design processes and STEM disciplinary knowledge to plan, sketch, then construct a building designed to withstand earthquake damage, taking into account a number of…