NASA Technical Reports Server (NTRS)
1987-01-01
Potential applications of robots for cost effective commercial microelectronic processes in space were studied and the associated robotic requirements were defined. Potential space application areas include advanced materials processing, bulk crystal growth, and epitaxial thin film growth and related processes. All possible automation of these processes was considered, along with energy and environmental requirements. Aspects of robot capabilities considered include system intelligence, ROM requirements, kinematic and dynamic specifications, sensor design and configuration, flexibility and maintainability. Support elements discussed included facilities, logistics, ground support, launch and recovery, and management systems.
Effect of processing on Polymer/Composite structure and properties
NASA Technical Reports Server (NTRS)
1982-01-01
Advances in the vitality and economic health of the field of polymer forecasting are discussed. A consistent and rational point of view which considers processing as a participant in the underlying triad of relationships which comprise materials science and engineering is outlined. This triad includes processing as it influences material structure, and ultimately properties. Methods in processing structure properties, polymer science and engineering, polymer chemistry and synthesis, structure and modification and optimization through processing, and methods of melt flow modeling in processing structure property relations of polymer were developed. Mechanical properties of composites are considered, and biomedical materials research to include polymer processing effects are studied. An analysis of the design technology of advances graphite/epoxy composites is also reported.
NASA Technical Reports Server (NTRS)
Knightly, W. F.
1980-01-01
About fifty industrial processes from the largest energy consuming sectors were used as a basis for matching a similar number of energy conversion systems that are considered as candidate which can be made available by the 1985 to 2000 time period. The sectors considered included food, textiles, lumber, paper, chemicals, petroleum, glass, and primary metals. The energy conversion systems included steam and gas turbines, diesels, thermionics, stirling, closed cycle and steam injected gas turbines, and fuel cells. Fuels considered were coal, both coal and petroleum based residual and distillate liquid fuels, and low Btu gas obtained through the on site gasification of coal. Computer generated reports of the fuel consumption and savings, capital costs, economics and emissions of the cogeneration energy conversion systems (ECS's) heat and power matched to the individual industrial processes are presented. National fuel and emissions savings are also reported for each ECS assuming it alone is implemented. Two nocogeneration base cases are included: coal fired and residual fired process boilers.
NASA Technical Reports Server (NTRS)
Knightly, W. F.
1980-01-01
About fifty industrial processes from the largest energy consuming sectors were used as a basis for matching a similar number of energy conversion systems that are considered as candidate which can be made available by the 1985 to 2000 time period. The sectors considered included food, textiles, lumber, paper, chemicals, petroleum, glass, and primary metals. The energy conversion systems included steam and gas turbines, diesels, thermionics, stirling, closed cycle and steam injected gas turbines, and fuel cells. Fuels considered were coal, both coal and petroleum based residual and distillate liquid fuels, and low Btu gas obtained through the on site gasification of coal. Computer generated reports of the fuels consumption and savings, capital costs, economics and emissions of the cogeneration energy conversion systems (ECS's) heat and power matched to the individual industrial processes are presented. National fuel and emissions savings are also reported for each ECS assuming it alone is implemented. Two nocogeneration base cases are included: coal fired and residual fired process boilers.
NASA Technical Reports Server (NTRS)
Knightly, W. F.
1980-01-01
About fifty industrial processes from the largest energy consuming sectors were used as a basis for matching a similar number of energy conversion systems that are considered as candidate which can be made available by the 1985 to 2000 time period. The sectors considered included food, textiles, lumber, paper, chemicals, petroleum, glass, and primary metals. The energy conversion systems included steam and gas turbines, diesels, thermionics, stirling, closed cycle and steam injected gas turbines, and fuel cells. Fuels considered were coal, both coal and petroleum based residual and distillate liquid fuels, and low Btu gas obtained through the on site gasification of coal. Computer generated reports of the fuel consumption and savings, capital costs, economics and emissions of the cogeneration energy conversion systems (ECS's) heat and power matched to the individual industrial processes are presented. National fuel and emissions savings are also reported for each ECS assuming it alone is implemented. Two nocogeneration base cases are included: coal fired and residual fired process boilers.
Neural substrates of decision-making.
Broche-Pérez, Y; Herrera Jiménez, L F; Omar-Martínez, E
2016-06-01
Decision-making is the process of selecting a course of action from among 2 or more alternatives by considering the potential outcomes of selecting each option and estimating its consequences in the short, medium and long term. The prefrontal cortex (PFC) has traditionally been considered the key neural structure in decision-making process. However, new studies support the hypothesis that describes a complex neural network including both cortical and subcortical structures. The aim of this review is to summarise evidence on the anatomical structures underlying the decision-making process, considering new findings that support the existence of a complex neural network that gives rise to this complex neuropsychological process. Current evidence shows that the cortical structures involved in decision-making include the orbitofrontal cortex (OFC), anterior cingulate cortex (ACC), and dorsolateral prefrontal cortex (DLPFC). This process is assisted by subcortical structures including the amygdala, thalamus, and cerebellum. Findings to date show that both cortical and subcortical brain regions contribute to the decision-making process. The neural basis of decision-making is a complex neural network of cortico-cortical and cortico-subcortical connections which includes subareas of the PFC, limbic structures, and the cerebellum. Copyright © 2014 Sociedad Española de Neurología. Published by Elsevier España, S.L.U. All rights reserved.
The limits of crop productivity
NASA Technical Reports Server (NTRS)
Bugbee, Bruce; Monje, Oscar
1992-01-01
The component processes that govern yield limits in food crops are reviewed and how each process can be individually measured is described. The processes considered include absorption of photosynthetic radiation by green tissue, carbon-fixation efficiency in photosynthesis, carbon use efficiency in respiration, biomass allocation to edible products, and efficiency of photosynthesis and respiration. The factors limiting yields in optimal environments are considered.
Anaerobic Digestion. Student Manual. Biological Treatment Process Control.
ERIC Educational Resources Information Center
Carnegie, John W., Ed.
This student manual contains the textual material for a four-lesson unit on anaerobic digestion control. Areas addressed include: (1) anaerobic sludge digestion (considering the nature of raw sludge, purposes of anaerobic digestion, the results of digestion, types of equipment, and other topics); (2) digester process control (considering feeding…
NASA Technical Reports Server (NTRS)
1975-01-01
The feasibility and possible advantages of processing materials in a nongravitational field are considered. Areas of investigation include biomedical applications, the processing of inorganic materials, and flight programs and funding.
76 FR 56107 - Requiring Use of Electronic Services by Certain Claimant Representatives
Federal Register 2010, 2011, 2012, 2013, 2014
2011-09-12
... ineligibility or personal preference, they can continue to use our paper processes and forms. Comment: A few... consider vocational factors; (3) * * * (ii) * * * This includes providing prompt and responsive answers to... need when we consider vocational factors; (3) * * * (ii) * * * This includes providing prompt and...
Choice of mathematical models for technological process of glass rod drawing
NASA Astrophysics Data System (ADS)
Alekseeva, L. B.
2017-10-01
The technological process of drawing glass rods (light guides) is considered. Automated control of the drawing process is reduced to the process of making decisions to ensure a given quality. The drawing process is considered as a control object, including the drawing device (control device) and the optical fiber forming zone (control object). To study the processes occurring in the formation zone, mathematical models are proposed, based on the continuum mechanics basics. To assess the influence of disturbances, a transfer function is obtained from the basis of the wave equation. Obtaining the regression equation also adequately describes the drawing process.
Orbital studies of lunar magnetism
NASA Technical Reports Server (NTRS)
Mcleod, M. G.; Coleman, P. J., Jr.
1982-01-01
Limitations of present lunar magnetic maps are considered. Optimal processing of satellite derived magnetic anomaly data is also considered. Studies of coastal and core geomagnetism are discussed. Lunar remanent and induced lunar magnetization are included.
Physical Processes in the MAGO/MFT Systems
DOE Office of Scientific and Technical Information (OSTI.GOV)
Garanin, Sergey F; Reinovsky, Robert E.
2015-03-23
The Monograph is devoted to theoretical discussion of the physical effects, which are most significant for the alternative approach to the problem of controlled thermonuclear fusion (CTF): the MAGO/MTF approach. The book includes the description of the approach, its difference from the major CTF systems—magnetic confinement and inertial confinement systems. General physical methods of the processes simulation in this approach are considered, including plasma transport phenomena and radiation, and the theory of transverse collisionless shock waves, the surface discharges theory, important for such kind of research. Different flows and magneto-hydrodynamic plasma instabilities occurring in the frames of this approach aremore » also considered. In virtue of the general physical essence of the considered phenomena the presented results are applicable to a wide range of plasma physics and hydrodynamics processes. The book is intended for the plasma physics and hydrodynamics specialists, post-graduate students, and senior students-physicists.« less
Modeling of Solid Waste Processing Options in BIO-Plex
NASA Technical Reports Server (NTRS)
Rodriguez, Luis F.; Finn, Cory; Kang, Sukwon; Hogan, John; Luna, Bernadette (Technical Monitor)
2000-01-01
BIO-Plex is a ground-based test bed currently under development by NASA for testing technologies and practices that may be utilized in future long-term life support missions. All aspects of such an Advanced Life Support (ALS) System must be considered to confidently construct a reliable system, which will not only allow the crew to survive in harsh environments, but allow the crew time to perform meaningful research. Effective handling of solid wastes is a critical aspect of the system, especially when recovery of resources contained in the waste is required. This is particularly important for ALS Systems configurations that include a Biomass Production Chamber. In these cases, significant amounts of inedible biomass waste may be produced, which can ultimately serve as a repository of necessary resources for sustaining life, notably carbon, water, and plant nutrients. Numerous biological and physicochemical solid waste processing options have been considered. Biological options include composting, aerobic digestion, and anaerobic digestion. Physicochemical options include pyrolysis, SCWO (supercritical water oxidation), various incineration configurations, microwave incineration, magnetically assisted gasification, and low temperature plasma reaction. Modeling of these options is a necessary step to assist in the design process. A previously developed top-level model of BIO-Plex implemented in MATLAB Simulink (r) for the use of systems analysis and design has been adopted for this analysis. Presently, this model only considered incineration for solid waste processing. Present work, reported here, includes the expansion of this model to include a wider array of solid waste processing options selected from the above options, bearing in mind potential, near term solid waste treatment systems. Furthermore, a trade study has also been performed among these solid waste processing technologies in an effort to determine the ideal technology for long-term life support missions.
ERIC Educational Resources Information Center
Emde, Robert N.
1992-01-01
Considers contributions of Sigmund Freud and Rene Spitz to developmental psychology. Freud's contributions include his observations about play, perspectives on developmental processes, and ideas about unconscious mental activity. Spitz's contributions include his assessments of infants, perspectives on developmental processes, and his concept of…
Proposal for a Security Management in Cloud Computing for Health Care
Dzombeta, Srdan; Brandis, Knud
2014-01-01
Cloud computing is actually one of the most popular themes of information systems research. Considering the nature of the processed information especially health care organizations need to assess and treat specific risks according to cloud computing in their information security management system. Therefore, in this paper we propose a framework that includes the most important security processes regarding cloud computing in the health care sector. Starting with a framework of general information security management processes derived from standards of the ISO 27000 family the most important information security processes for health care organizations using cloud computing will be identified considering the main risks regarding cloud computing and the type of information processed. The identified processes will help a health care organization using cloud computing to focus on the most important ISMS processes and establish and operate them at an appropriate level of maturity considering limited resources. PMID:24701137
Proposal for a security management in cloud computing for health care.
Haufe, Knut; Dzombeta, Srdan; Brandis, Knud
2014-01-01
Cloud computing is actually one of the most popular themes of information systems research. Considering the nature of the processed information especially health care organizations need to assess and treat specific risks according to cloud computing in their information security management system. Therefore, in this paper we propose a framework that includes the most important security processes regarding cloud computing in the health care sector. Starting with a framework of general information security management processes derived from standards of the ISO 27000 family the most important information security processes for health care organizations using cloud computing will be identified considering the main risks regarding cloud computing and the type of information processed. The identified processes will help a health care organization using cloud computing to focus on the most important ISMS processes and establish and operate them at an appropriate level of maturity considering limited resources.
NASA Astrophysics Data System (ADS)
Karmazikov, Y. V.; Fainberg, E. M.
2005-06-01
Work with DICOM compatible equipment integrated into hardware and software systems for medical purposes has been considered. Structures of process of reception and translormation of the data are resulted by the example of digital rentgenography and angiography systems, included in hardware-software complex DIMOL-IK. Algorithms of reception and the analysis of the data are offered. Questions of the further processing and storage of the received data are considered.
Key Elements of Protection for Military Textiles
2010-10-15
responsibility for the accuracy, completeness, or usefulness of any information, apparatus, product, or process disclosed, or represents that its use would...future for each aspect of protection are given. Aspects of protection considered are limited to threats from human adversaries and include camouflage...of protection considered are limited to threats from human adversaries and include camoufl age, ballistic protection and protection from toxic
Bayesian Computation for Log-Gaussian Cox Processes: A Comparative Analysis of Methods
Teng, Ming; Nathoo, Farouk S.; Johnson, Timothy D.
2017-01-01
The Log-Gaussian Cox Process is a commonly used model for the analysis of spatial point pattern data. Fitting this model is difficult because of its doubly-stochastic property, i.e., it is an hierarchical combination of a Poisson process at the first level and a Gaussian Process at the second level. Various methods have been proposed to estimate such a process, including traditional likelihood-based approaches as well as Bayesian methods. We focus here on Bayesian methods and several approaches that have been considered for model fitting within this framework, including Hamiltonian Monte Carlo, the Integrated nested Laplace approximation, and Variational Bayes. We consider these approaches and make comparisons with respect to statistical and computational efficiency. These comparisons are made through several simulation studies as well as through two applications, the first examining ecological data and the second involving neuroimaging data. PMID:29200537
The Role of Reader Characteristics in Processing and Learning from Informational Text
ERIC Educational Resources Information Center
Fox, Emily
2009-01-01
This article considers the role of reader characteristics in processing and learning from informational text, as revealed in think-aloud research. A theoretical framework for relevant aspects of readers' processing and products was developed. These relevant aspects included three attentional foci for processing (comprehension, monitoring, and…
Cogeneration Technology Alternatives Study (CTAS). Volume 3: Industrial processes
NASA Technical Reports Server (NTRS)
Palmer, W. B.; Gerlaugh, H. E.; Priestley, R. R.
1980-01-01
Cogenerating electric power and process heat in single energy conversion systems rather than separately in utility plants and in process boilers is examined in terms of cost savings. The use of various advanced energy conversion systems are examined and compared with each other and with current technology systems for their savings in fuel energy, costs, and emissions in individual plants and on a national level. About fifty industrial processes from the target energy consuming sectors were used as a basis for matching a similar number of energy conversion systems that are considered as candidate which can be made available by the 1985 to 2000 time period. The sectors considered included food, textiles, lumber, paper, chemicals, petroleum, glass, and primary metals. The energy conversion systems included steam and gas turbines, diesels, thermionics, stirling, closed cycle and steam injected gas turbines, and fuel cells. Fuels considered were coal, both coal and petroleum based residual and distillate liquid fuels, and low Btu gas obtained through the on site gasification of coal. An attempt was made to use consistent assumptions and a consistent set of ground rules specified by NASA for determining performance and cost. Data and narrative descriptions of the industrial processes are given.
Chemical Changes in Carbohydrates Produced by Thermal Processing.
ERIC Educational Resources Information Center
Hoseney, R. Carl
1984-01-01
Discusses chemical changes that occur in the carbohydrates found in food products when these products are subjected to thermal processing. Topics considered include browning reactions, starch found in food systems, hydrolysis of carbohydrates, extrusion cooking, processing of cookies and candies, and alterations in gums. (JN)
Alternatives Analysis for the Resumption of Transient Testing Program
DOE Office of Scientific and Technical Information (OSTI.GOV)
Lee Nelson
2013-11-01
An alternatives analysis was performed for resumption of transient testing. The analysis considered eleven alternatives – including both US international facilities. A screening process was used to identify two viable alternatives from the original eleven. In addition, the alternatives analysis includes a no action alternative as required by the National Environmental Policy Act (NEPA). The alternatives considered in this analysis included: 1. Restart the Transient Reactor Test Facility (TREAT) 2. Modify the Annular Core Research Reactor (ACRR) which includes construction of a new hot cell and installation of a new hodoscope. 3. No Action
Super and parallel computers and their impact on civil engineering
DOE Office of Scientific and Technical Information (OSTI.GOV)
Kamat, M.P.
1986-01-01
This book presents the papers given at a conference on the use of supercomputers in civil engineering. Topics considered at the conference included solving nonlinear equations on a hypercube, a custom architectured parallel processing system, distributed data processing, algorithms, computer architecture, parallel processing, vector processing, computerized simulation, and cost benefit analysis.
Requirements to the procedure and stages of innovative fuel development
NASA Astrophysics Data System (ADS)
Troyanov, V.; Zabudko, L.; Grachyov, A.; Zhdanova, O.
2016-04-01
According to the accepted current understanding under the nuclear fuel we will consider the assembled active zone unit (Fuel assembly) with its structural elements, fuel rods, pellet column, structural materials of fuel rods and fuel assemblies. The licensing process includes justification of safe application of the proposed modifications, including design-basis and experimental justification of the modified items under normal operating conditions and in violation of normal conditions, including accidents as well. Besides the justification of modified units itself, it is required to show the influence of modifications on the performance and safety of the other Reactor Unit’ and Nuclear Plant’ elements (e.g. burst can detection system, transportation and processing operations during fuel handling), as well as to justify the new standards of fuel storage etc. Finally, the modified fuel should comply with the applicable regulations, which often becomes a very difficult task, if only because those regulations, such as the NP-082-07, are not covered modification issues. Making amendments into regulations can be considered as the only solution, but the process is complicated and requires deep grounds for amendments. Some aspects of licensing new nuclear fuel are considered the example of mixed nitride uranium -plutonium fuel application for the BREST reactor unit.
Reducing the Teacher Workforce: A Management Perspective.
ERIC Educational Resources Information Center
Collins, Philip; Nelson, Dorothy Q.
1983-01-01
Discusses substantive and procedural restraints, including legal pitfalls, due process, and no-layoff clauses, within which public employers must decide questions of reduction in workforce (RIF). Describes elements of a sound RIF policy and considers ways of using the collective bargaining process to facilitate the RIF process. (JBM)
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
The Performance Prototype Trough (PPT) Concentrating Collector consists of four 80-foot modules in a 320-foot row. The collector was analyzed, including cost estimates and manufacturing processes to produce collectors in volumes from 100 to 100,000 modules per year. The four different reflector concepts considered were the sandwich reflector structure, sheet metal reflector structure, molded reflector structure, and glass laminate structure. The sheet metal and glass laminate structures are emphasized with their related structure concepts. A preliminary manufacturing plan is offered that includes: documentation of the manufacturing process with production flow diagrams; labor and material costs at various production levels; machinerymore » and equipment requirements including preliminary design specifications; and capital investment costs for a new plant. Of five reflector designs considered, the two judged best and considered at length are thin annealed glass and steel laminate on steel frame panel and thermally sagged glass. Also discussed are market considerations, costing and selling price estimates, design cost analysis and make/buy analysis. (LEW)« less
Evaluation and purchase of confocal microscopes: numerous factors to consider.
Zucker, Robert M; Chua, Michael
2010-10-01
The purchase of a confocal microscope is a difficult decision. Many factors need to be considered, which include hardware, software, company, support, service, and price. These issues are discussed to help guide the purchasing process. © 2010 by John Wiley & Sons, Inc.
Old Assumptions, New Paradigms: Technology, Group Process, and Continuing Professional Education.
ERIC Educational Resources Information Center
Healey, Kathryn N.; Lawler, Patricia A.
2002-01-01
Continuing educators must consider the impact of technology on group processes, including ways in which it affects group pressures, communication patterns, and social and emotional components of learning. Administrators and faculty should integrate group process frameworks with educational technologies in order to provide effective learning…
Applications of aerospace technology in industry. A technology transfer profile: Food technology
NASA Technical Reports Server (NTRS)
Murray, D. M.
1971-01-01
Food processing and preservation technologies are reviewed, expected technological advances are considered including processing and market factors. NASA contributions to food technology and nutrition are presented with examples of transfer from NASA to industry.
NASA Technical Reports Server (NTRS)
Knightly, W. F.
1980-01-01
Various advanced energy conversion systems (ECS) are compared with each other and with current technology systems for their savings in fuel energy, costs, and emissions in individual plants and on a national level. About fifty industrial processes from the largest energy consuming sectors were used as a basis for matching a similar number of energy conversion systems that are considered as candidates which can be made available by the 1985 to 2000 time period. The sectors considered included food, textiles, lumber, paper, chemicals, petroleum, glass, and primary metals. The energy conversion systems included steam and gas turbines, diesels, thermionics, stirling, closed cycle and steam injected gas turbines, and fuel cells. Fuels considered were coal, both coal and petroleum based residual and distillate liquid fuels, and low Btu gas obtained through the on-site gasification of coal. Computer generated reports of the fuel consumption and savings, capital costs, economics and emissions of the cogeneration energy conversion systems (ECS's) heat and power matched to the individual industrial processes are presented for coal fired process boilers. National fuel and emissions savings are also reported for each ECS assuming it alone is implemented.
Managing Technological Change in Libraries and Information Services.
ERIC Educational Resources Information Center
Klobas, Jane E.
1990-01-01
Examines factors to be considered in the management of technological change in libraries and information services. The organizational climate for change is discussed, and factors to consider when developing a strategy for introducing a new product, service, or system are described, including leadership, goals, political processes, marketing, and…
78 FR 66916 - Alaskan Seafood Processing Effluent Limitations Guidelines
Federal Register 2010, 2011, 2012, 2013, 2014
2013-11-07
... discharges which EPA is considering whether to promulgate in final form. DATES: Comments on this Notice, as... consider your comment. Electronic files should avoid the use of special characters, any form of encryption... data took the form of a questionnaire that included the following topics: general information about the...
Code of Federal Regulations, 2014 CFR
2014-07-01
... § 93.122. (6) A process for consulting on the design, schedule, and funding of research and data... highway travel), and which projects should be considered to have a significant change in design concept... locations, design concept and scope, or the no-build option are still being considered), including those by...
Code of Federal Regulations, 2011 CFR
2011-07-01
... § 93.122. (6) A process for consulting on the design, schedule, and funding of research and data... highway travel), and which projects should be considered to have a significant change in design concept... locations, design concept and scope, or the no-build option are still being considered), including those by...
Code of Federal Regulations, 2012 CFR
2012-07-01
... § 93.122. (6) A process for consulting on the design, schedule, and funding of research and data... highway travel), and which projects should be considered to have a significant change in design concept... locations, design concept and scope, or the no-build option are still being considered), including those by...
Code of Federal Regulations, 2010 CFR
2010-07-01
... § 93.122. (6) A process for consulting on the design, schedule, and funding of research and data... highway travel), and which projects should be considered to have a significant change in design concept... locations, design concept and scope, or the no-build option are still being considered), including those by...
Code of Federal Regulations, 2013 CFR
2013-07-01
... § 93.122. (6) A process for consulting on the design, schedule, and funding of research and data... highway travel), and which projects should be considered to have a significant change in design concept... locations, design concept and scope, or the no-build option are still being considered), including those by...
Clinical process in an integrative psychotherapy for self-wounds.
Wolfe, Barry E
2013-09-01
In this article, I will briefly describe the clinical process of an integrative psychotherapy for the healing of self-wounds, including its intended interventions and the variability of their application and outcome. Four specific strategies will be considered, including (a) the role of empathy throughout the course of therapy; (b) exposure therapy as a paradigmatic treatment for the treatment of feared thoughts, behavior, and emotions; (c) focusing and other experiential interventions for eliciting self-wounds; and (d) modification and healing of self-wounds with an individualized array of psychodynamic, experiential, and cognitive-behavioral strategies. In addition, we will briefly consider the impact of transference and countertransference on the trajectory of therapy. 2013 APA, all rights reserved
ERIC Educational Resources Information Center
Castellan, N. John, Jr., Ed.; And Others
The conference papers in this collection emphasize the theoretical significance of their authors' work in the areas of mathematical and cognitive psychology. Major topics considered include facilitation of problem solving; psychological differences among problem isomorphs; the process of understanding in problem solving; processing information for…
On Becoming Faculty Librarians: Acculturation Problems and Remedies.
ERIC Educational Resources Information Center
Mitchell, W. Bede; Morton, Bruce
1992-01-01
Discussion of the acculturation of academic librarians to faculty positions focuses on the processes of acculturation, including selection, sequestration, instruction and apprenticeship, sanctioning, certification and sponsorship, and mentoring. Difficulties with this process specific to librarians are considered, and suggestions for improving…
Solid propellant processing factor in rocket motor design
NASA Technical Reports Server (NTRS)
1971-01-01
The ways are described by which propellant processing is affected by choices made in designing rocket engines. Tradeoff studies, design proof or scaleup studies, and special design features are presented that are required to obtain high product quality, and optimum processing costs. Processing is considered to include the operational steps involved with the lining and preparation of the motor case for the grain; the procurement of propellant raw materials; and propellant mixing, casting or extrusion, curing, machining, and finishing. The design criteria, recommended practices, and propellant formulations are included.
Visual dysfunction in Parkinson’s disease
Weil, Rimona S.; Schrag, Anette E.; Warren, Jason D.; Crutch, Sebastian J.; Lees, Andrew J.; Morris, Huw R.
2016-01-01
Patients with Parkinson’s disease have a number of specific visual disturbances. These include changes in colour vision and contrast sensitivity and difficulties with complex visual tasks such as mental rotation and emotion recognition. We review changes in visual function at each stage of visual processing from retinal deficits, including contrast sensitivity and colour vision deficits to higher cortical processing impairments such as object and motion processing and neglect. We consider changes in visual function in patients with common Parkinson’s disease-associated genetic mutations including GBA and LRRK2. We discuss the association between visual deficits and clinical features of Parkinson’s disease such as rapid eye movement sleep behavioural disorder and the postural instability and gait disorder phenotype. We review the link between abnormal visual function and visual hallucinations, considering current models for mechanisms of visual hallucinations. Finally, we discuss the role of visuo-perceptual testing as a biomarker of disease and predictor of dementia in Parkinson’s disease. PMID:27412389
ERIC Educational Resources Information Center
Crouse, Janice Shaw; Crouse, Gilbert L.
Communication scholars have only recently begun to consider internal processes of thought as essential components of interpersonal communication. In 1964 a reorientation of thinking to include intrapersonal processes as integral to the communication process was first urged. The "hidden other" refers to the wellspring of the mind and its…
Rathbun, R.E.; Stephens, D.W.; Shultz, D.J.
1982-01-01
The physical, chemical, and biological processes that might affect the concentration of acetone in water were investigated in laboratory studies. Processes considered included volatilization, adsorption by sediments, photodecomposition, bacterial degradation, and absorption by algae and molds. It was concluded that volatilization and bacterial degradation were the dominant processes determining the fate of acetone in streams and rivers. ?? 1982.
75 FR 57230 - 340B Drug Pricing Program Manufacturer Civil Monetary Penalties
Federal Register 2010, 2011, 2012, 2013, 2014
2010-09-20
... process incorporating a variety of elements to gather and consider grounds for applying the penalty..., including, but not limited to: Decision-making individual or make-up of the decision making body; ex parte... Process Elements HRSA is seeking comments on the administrative processes that would best administer civil...
17 CFR 202.190 - Public Company Accounting Oversight Board budget approval process.
Code of Federal Regulations, 2013 CFR
2013-04-01
... information technology projects; and (viii) A statement that the PCAOB has considered relative costs and..., processes, staff skills, information and other technologies, human resources, capital assets, and other... include, among others: personnel, training, recruiting and relocation expenses, information technology...
17 CFR 202.190 - Public Company Accounting Oversight Board budget approval process.
Code of Federal Regulations, 2014 CFR
2014-04-01
... information technology projects; and (viii) A statement that the PCAOB has considered relative costs and..., processes, staff skills, information and other technologies, human resources, capital assets, and other... include, among others: personnel, training, recruiting and relocation expenses, information technology...
40 CFR 33.301 - What does this subpart require?
Code of Federal Regulations, 2010 CFR
2010-07-01
... through outreach and recruitment activities. For Indian Tribal, State and Local and Government recipients... facilitates participation by DBEs in the competitive process. This includes, whenever possible, posting.... (c) Consider in the contracting process whether firms competing for large contracts could subcontract...
Relational Knowledge in Higher Cognitive Processes.
ERIC Educational Resources Information Center
Halford, Graeme S.
Explicit representation of relations plays some role in virtually all higher cognitive processes, but relational knowledge has seldom been investigated systematically. This paper considers how relational knowledge is involved in some tasks that have been important to cognitive development, including transitivity, the balance scale, classification…
Chemical vapor deposition for automatic processing of integrated circuits
NASA Technical Reports Server (NTRS)
Kennedy, B. W.
1980-01-01
Chemical vapor deposition for automatic processing of integrated circuits including the wafer carrier and loading from a receiving air track into automatic furnaces and unloading on to a sending air track is discussed. Passivation using electron beam deposited quartz is also considered.
Connecting Photosynthesis and Cellular Respiration: Preservice Teachers' Conceptions
ERIC Educational Resources Information Center
Brown, Mary H.; Schwartz, Renee S.
2009-01-01
The biological processes of photosynthesis and plant cellular respiration include multiple biochemical steps, occur simultaneously within plant cells, and share common molecular components. Yet, learners often compartmentalize functions and specialization of cell organelles relevant to these two processes, without considering the interconnections…
PROCEEDINGS: SYMPOSIUM ON FLUE GAS DESULFURIZATION - NEW ORLEANS, MARCH 1976, VOLUME I
The proceedings document the presentation made during the symposium, which dealt with the status of flue gas desulfurization technology in the United States and abroad. Subjects considered included: regenerable, nonregenerable, and advanced processes; process costs; and by-produc...
PROCEEDINGS: SYMPOSIUM ON FLUE GAS DESULFURIZATION-NEW ORLEANS, MARCH 1976. VOLUME II
The proceedings document the presentations made during the symposium, which dealt with the status of flue gas desulfurization technology in the United States and abroad. Subjects considered included: regenerable, non-regenerable, and advanced processes; process costs; and by-prod...
The Drug Reimbursement Decision-Making System in Iran.
Ansaripour, Amir; Uyl-de Groot, Carin A; Steenhoek, Adri; Redekop, William K
2014-05-01
Previous studies of health policies in Iran have not focused exclusively on the drug reimbursement process. The aim of this study was to describe the entire drug reimbursement process and the stakeholders, and discuss issues faced by policymakers. Review of documents describing the administrative rules and directives of stakeholders, supplemented by published statistics and interviews with experts and policymakers. Iran has a systematic process for the assessment, appraisal, and judgment of drug reimbursements. The two most important organizations in this process are the Food and Drug Organization, which considers clinical effectiveness, safety, and economic issues, and the Supreme Council of Health Insurance, which considers various criteria, including budget impact and cost-effectiveness. Ultimately, the Iranian Cabinet approves a drug and recommends its use to all health insurance organizations. Reimbursed drugs account for about 53.5% of all available drugs and 77.3% of drug expenditures. Despite its strengths, the system faces various issues, including conflicting stakeholder aims, lengthy decision-making duration, limited access to decision-making details, and rigidity in the assessment process. The Iranian drug reimbursement system uses decision-making criteria and a structured approach similar to those in other countries. Important shortcomings in the system include out-of-pocket contributions due to lengthy decision making, lack of transparency, and conflicting interests among stakeholders. Iranian policymakers should consider a number of ways to remedy these problems, such as case studies of individual drugs and closer examination of experiences in other countries. Copyright © 2014 International Society for Pharmacoeconomics and Outcomes Research (ISPOR). Published by Elsevier Inc. All rights reserved.
Cogeneration Technology Alternatives Study (CTAS). Volume 5: Cogeneration systems results
NASA Technical Reports Server (NTRS)
Gerlaugh, H. E.; Hall, E. W.; Brown, D. H.; Priestley, R. R.; Knightly, W. F.
1980-01-01
The use of various advanced energy conversion systems is examined and compared with each other and with current technology systems for savings in fuel energy, costs, and emissions in individual plants and on a national level. About fifty industrial processes from the largest energy consuming sectors were used as a basis for matching a similar number of energy conversion systems that are considered as candidate which can be made available by the 1985 to 2000 time period. The sectors considered included food, textiles, lumber, paper, chemicals, petroleum, glass, and primary metals. The energy conversion systems included steam and gas turbines, diesels, thermionics, stirling, closed cycle and steam injected gas turbines, and fuel cells. Fuels considered were coal, both coal and petroleum based residual and distillate liquid fuels, and low Btu gas obtained through the on site gasification of coal. The methodology and results of matching the cogeneration energy conversion systems to approximately 50 industrial processes are described. Results include fuel energy saved, levelized annual energy cost saved, return on investment, and operational factors relative to the noncogeneration base cases.
ERIC Educational Resources Information Center
Lunetta, Vincent N.; And Others
1984-01-01
Advocates including environmental issues balanced with basic science concepts/processes to provide a sound science foundation. Suggests case studies of regional environmental issues to sensitize/motivate students while reflecting complex nature of science/society issues. Issues considered include: fresh water quality, earthquake predication,…
Instructional Strategy: Didactic Media Presentation to Optimize Student Learning
ERIC Educational Resources Information Center
Schilling, Jim
2017-01-01
Context: Subject matter is presented to athletic training students in the classroom using various modes of media. The specific type of mode and when to use it should be considered to maximize learning effectiveness. Other factors to consider in this process include a student's knowledge base and the complexity of material. Objective: To introduce…
Space Station: Key to the Future.
ERIC Educational Resources Information Center
National Aeronautics and Space Administration, Washington, DC.
The possible applications, advantages and features of an advanced space station to be developed are considered in a non-technical manner in this booklet. Some of the areas of application considered include the following: the detection of large scale dynamic earth processes such as changes in snow pack, crops, and air pollution levels; the…
Ethanol or Biodiesel? A Systems-Analysis Decision
ERIC Educational Resources Information Center
Dinan, Frank; Stabler, Tom
2008-01-01
This case study stresses the need to broadly consider an entire system, including all of the energy inputs and outputs involved, to determine the real efficiency of that system. It also asks its student audience to consider the role that scientific input plays in policy decision-making processes. It emphasizes that, despite the importance of this…
The proceedings document presentations made during the symposium, which dealt with the status of flue gas desulfurization technology in the United States and abroad. Subjects considered included: regenerable, non-regenerable, and advanced processes; process costs; and by-product ...
The proceedings document presentations made during the symposium, which dealt with the status of flue gas desulfurization technology in the United States and abroad. Subjects considered included: regenerable, non-regenerable, and advanced processes; process costs; and by-product ...
Steele, Muriel M; Anctil, Annick; Ladner, David A
2014-05-01
Algaculture has the potential to be a sustainable option for nutrient removal at wastewater treatment plants. The purpose of this study was to compare the environmental impacts of three likely algaculture integration strategies to a conventional nutrient removal strategy. Process modeling was used to determine life cycle inventory data and a comparative life cycle assessment was used to determine environmental impacts. Treatment scenarios included a base case treatment plant without nutrient removal, a plant with conventional nutrient removal, and three other cases with algal unit processes placed at the head of the plant, in a side stream, and at the end of the plant, respectively. Impact categories included eutrophication, global warming, ecotoxicity, and primary energy demand. Integrating algaculture prior to activated sludge proved to be most beneficial of the scenarios considered for all impact categories; however, this scenario would also require primary sedimentation and impacts of that unit process should be considered for implementation of such a system.
An industrial ecology approach to municipal solid waste ...
Municipal solid waste (MSW) can be viewed as a feedstock for industrial ecology inspired conversions of wastes to valuable products and energy. The industrial ecology principle of symbiotic processes using waste streams for creating value-added products is applied to MSW, with examples suggested for various residual streams. A methodology is presented to consider individual waste-to-energy or waste-to-product system synergies, evaluating the economic and environmental issues associated with each system. Steps included in the methodology include identifying waste streams, specific waste components of interest, and conversion technologies, plus steps for determining the economic and environmental effects of using wastes and changes due to transport, administrative handling, and processing. In addition to presenting the methodology, technologies for various MSW input streams are categorized as commercialized or demonstrated to provide organizations that are considering processes for MSW with summarized information. The organization can also follow the methodology to analyze interesting processes. Presents information useful for analyzing the sustainability of alternatives for the management of municipal solid waste.
Koziol, Leonard F; Budding, Deborah Ely; Chidekel, Dana
2010-12-01
Current cortico-centric models of cognition lack a cohesive neuroanatomic framework that sufficiently considers overlapping levels of function, from "pathological" through "normal" to "gifted" or exceptional ability. While most cognitive theories presume an evolutionary context, few actively consider the process of adaptation, including concepts of neurodevelopment. Further, the frequent co-occurrence of "gifted" and "pathological" function is difficult to explain from a cortico-centric point of view. This comprehensive review paper proposes a framework that includes the brain's vertical organization and considers "giftedness" from an evolutionary and neurodevelopmental vantage point. We begin by discussing the current cortico-centric model of cognition and its relationship to intelligence. We then review an integrated, dual-tiered model of cognition that better explains the process of adaptation by simultaneously allowing for both stimulus-based processing and higher-order cognitive control. We consider the role of the basal ganglia within this model, particularly in relation to reward circuitry and instrumental learning. We review the important role of white matter tracts in relation to speed of adaptation and development of behavioral mastery. We examine the cerebellum's critical role in behavioral refinement and in cognitive and behavioral automation, particularly in relation to expertise and giftedness. We conclude this integrated model of brain function by considering the savant syndrome, which we believe is best understood within the context of a dual-tiered model of cognition that allows for automaticity in adaptation as well as higher-order executive control.
Liddell, Belinda J.; Jobson, Laura
2016-01-01
A significant body of literature documents the neural mechanisms involved in the development and maintenance of posttraumatic stress disorder (PTSD). However, there is very little empirical work considering the influence of culture on these underlying mechanisms. Accumulating cultural neuroscience research clearly indicates that cultural differences in self-representation modulate many of the same neural processes proposed to be aberrant in PTSD. The objective of this review paper is to consider how culture may impact on the neural mechanisms underlying PTSD. We first outline five key affective and cognitive functions and their underlying neural correlates that have been identified as being disrupted in PTSD: (1) fear dysregulation; (2) attentional biases to threat; (3) emotion and autobiographical memory; (4) self-referential processing; and (5) attachment and interpersonal processing. Second, we consider prominent cultural theories and review the empirical research that has demonstrated the influence of cultural variations in self-representation on the neural substrates of these same five affective and cognitive functions. Finally, we propose a conceptual model that suggests that these five processes have major relevance to considering how culture may influence the neural processes underpinning PTSD. Highlights of the article Cultural variations in individualistic-collectivistic self-representation modulate many of the same neural and psychological processes disrupted in PTSD. These commonly affected processes include fear perception and regulation mechanisms, attentional biases (to threat), emotional and autobiographical memory systems, self-referential processing and attachment systems. A conceptual model is proposed whereby culture is considered integral to the development and maintenance of PTSD and its neural substrates. PMID:27302635
Counseling the Elderly: A Lifetime Process.
ERIC Educational Resources Information Center
Ponzo, Zander
1981-01-01
Discusses aspects of age prejudice including: age restrictiveness, age distortion, and ageism. Considers social changes related to age prejudice. Describes a University of Vermont course in age prejudice. Includes a table listing cognitive, affective, and behavioral objectives for the reduction of age discrimination. (RC)
33 CFR 1.05-10 - Regulatory process overview.
Code of Federal Regulations, 2011 CFR
2011-07-01
... regulation, alternatives considered, and potential cost and benefits, including possible environmental... or for changes to an existing regulation. The need may arise due to statutory changes, or be based on... Federal Register. These may include regulatory evaluations, environmental analyses, requests for comments...
33 CFR 1.05-10 - Regulatory process overview.
Code of Federal Regulations, 2010 CFR
2010-07-01
... regulation, alternatives considered, and potential cost and benefits, including possible environmental... or for changes to an existing regulation. The need may arise due to statutory changes, or be based on... Federal Register. These may include regulatory evaluations, environmental analyses, requests for comments...
Desktop Publishing Choices: Making an Appropriate Decision.
ERIC Educational Resources Information Center
Crawford, Walt
1991-01-01
Discusses various choices available for desktop publishing systems. Four categories of software are described, including advanced word processing, graphics software, low-end desktop publishing, and mainstream desktop publishing; appropriate hardware is considered; and selection guidelines are offered, including current and future publishing needs,…
Simultaneous and Successive Processing in Children with Reading Disability.
ERIC Educational Resources Information Center
Das, J. P.
1984-01-01
Considered are implications for learning disabled students of the simultaneous, successive, and planning (SSP) model, a model of information integration that emphasizes processes rather than ability. Remedial training guidelines are offered, including assessment of learning potential and determination of the nature of the weakness and its…
NASA Technical Reports Server (NTRS)
Haratunian, M.
1985-01-01
A system of access platforms and equipment within the space shuttle orbiter processing facility at Kennedy Space Center is described. The design challenges of the platforms, including clearance envelopes, load criteria, and movement, are discussed. Various applications of moveable platforms are considered.
Design Guidelines for CAI Authoring Systems.
ERIC Educational Resources Information Center
Hunka, S.
1989-01-01
Discussion of the use of authoring systems for courseware development focuses on guidelines to be considered when designing authoring systems. Topics discussed include allowing a variety of instructional strategies; interaction with peripheral processes such as student records; the editing process; and human factors in computer interface design,…
Numerical modeling of laser assisted tape winding process
NASA Astrophysics Data System (ADS)
Zaami, Amin; Baran, Ismet; Akkerman, Remko
2017-10-01
Laser assisted tape winding (LATW) has become more and more popular way of producing new thermoplastic products such as ultra-deep sea water riser, gas tanks, structural parts for aerospace applications. Predicting the temperature in LATW has been a source of great interest since the temperature at nip-point plays a key role for mechanical interface performance. Modeling the LATW process includes several challenges such as the interaction of optics and heat transfer. In the current study, numerical modeling of the optical behavior of laser radiation on circular surfaces is investigated based on a ray tracing and non-specular reflection model. The non-specular reflection is implemented considering the anisotropic reflective behavior of the fiber-reinforced thermoplastic tape using a bidirectional reflectance distribution function (BRDF). The proposed model in the present paper includes a three-dimensional circular geometry, in which the effects of reflection from different ranges of the circular surface as well as effect of process parameters on temperature distribution are studied. The heat transfer model is constructed using a fully implicit method. The effect of process parameters on the nip-point temperature is examined. Furthermore, several laser distributions including Gaussian and linear are examined which has not been considered in literature up to now.
Salari-Moghaddam, Asma; Milajerdi, Alireza; Larijani, Bagher; Esmaillzadeh, Ahmad
2018-06-01
No earlier study has summarized findings from previous publications on processed red meat intake and risk of Chronic Obstructive Pulmonary Disease (COPD). This systematic review and meta-analysis was conducted to examine the association between processed red meat intake and COPD risk. We searched in PubMed/Medline, ISI Web of Knowledge, Scopus, EMBASE and Google Scholar up to April 2018 to identify relevant studies. Prospective cohort studies that considered processed red meat as the exposure variable and COPD as the main outcome variable or as one of the outcomes were included in the systematic review. Publications in which hazard ratios (HRs) were reported as effect size were included in the meta-analysis. Finally, five cohort studies were considered in this systematic review and meta-analysis. In total, 289,952 participants, including 8338 subjects with COPD, aged ≥27 years were included in the meta-analysis. These studies were from Sweden and the US. Linear dose response meta-analysis revealed that each 50 gr/week increase in processed red meat intake was associated with 8% higher risk of COPD (HR: 1.08; 95% CI: 1.03, 1.13). There was an evidence of non-linear association between processed red meat intake and risk of COPD (P < 0.001). In this systematic review and meta-analysis, we found a significant positive association between processed red meat intake and risk of COPD. CRD42017077971. Copyright © 2018 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved.
Aftercare Guidelines for Drug and Alcohol Program Advisors
1991-10-21
recovery process . Aftercare is the most critical part of this process ensuring productivity and maximization of resources. OPNAV Instruction 5350G-4...Aftercare is not a stand-alone program, it is part of a process . This process includes: (1) the harmful involvement with alcohol or other drugs or...she should understand all of the process . Three Phases The first three years after initial treatment are considered the most critical. Three phases take
Monitoring real-time navigation processes using the automated reasoning tool (ART)
NASA Technical Reports Server (NTRS)
Maletz, M. C.; Culbert, C. J.
1985-01-01
An expert system is described for monitoring and controlling navigation processes in real-time. The ART-based system features data-driven computation, accommodation of synchronous and asynchronous data, temporal modeling for individual time intervals and chains of time intervals, and hypothetical reasoning capabilities that consider alternative interpretations of the state of navigation processes. The concept is illustrated in terms of the NAVEX system for monitoring and controlling the high speed ground navigation console for Mission Control at Johnson Space Center. The reasoning processes are outlined, including techniques used to consider alternative data interpretations. Installation of the system has permitted using a single operator, instead of three, to monitor the ascent and entry phases of a Shuttle mission.
The CSI Academy: Encouraging Diverse Students to Consider Science Careers and Science Teaching
ERIC Educational Resources Information Center
Kaye, Karen; Turner, John F.; Emigh, James
2011-01-01
The CSI academies employed a multi-layered, collaborative approach to encourage diverse students to consider STEM careers, including science teaching. The academies recruited a diverse group of high school students. This was due, in large part, to the creation of a unique selection process that identified students with unrealized potential. The…
Educational Technology in Military Training Applications: A Current Assessment.
ERIC Educational Resources Information Center
Platt, William A.; Andrews, Dee H.
This chapter considers the history of instructional development (ID) in the military, with particular emphasis on the U.S. Navy. The ID process used at the Navy's Instructional Program Development Centers is presented, including the process for simulator development. An in-depth analysis of the problems encountered with educational technology…
40 CFR 61.348 - Standards: Treatment processes.
Code of Federal Regulations, 2013 CFR
2013-07-01
... enhanced biodegradation unit shall not be included in the calculation of the total annual benzene quantity, if the enhanced biodegradation unit is the first exempt unit in which the waste is managed or treated. A unit shall be considered enhanced biodegradation if it is a suspended-growth process that...
40 CFR 61.348 - Standards: Treatment processes.
Code of Federal Regulations, 2011 CFR
2011-07-01
... enhanced biodegradation unit shall not be included in the calculation of the total annual benzene quantity, if the enhanced biodegradation unit is the first exempt unit in which the waste is managed or treated. A unit shall be considered enhanced biodegradation if it is a suspended-growth process that...
40 CFR 61.348 - Standards: Treatment processes.
Code of Federal Regulations, 2012 CFR
2012-07-01
... enhanced biodegradation unit shall not be included in the calculation of the total annual benzene quantity, if the enhanced biodegradation unit is the first exempt unit in which the waste is managed or treated. A unit shall be considered enhanced biodegradation if it is a suspended-growth process that...
40 CFR 61.348 - Standards: Treatment processes.
Code of Federal Regulations, 2014 CFR
2014-07-01
... enhanced biodegradation unit shall not be included in the calculation of the total annual benzene quantity, if the enhanced biodegradation unit is the first exempt unit in which the waste is managed or treated. A unit shall be considered enhanced biodegradation if it is a suspended-growth process that...
Facultative Lagoons. Student Manual. Biological Treatment Process Control.
ERIC Educational Resources Information Center
Andersen, Lorri
The textual material for a unit on facultative lagoons is presented in this student manual. Topic areas discussed include: (1) loading; (2) microbial theory; (3) structure and design; (4) process control; (5) lagoon start-up; (6) data handling and analysis; (7) lagoon maintenance (considering visual observations, pond structure, safety, odor,…
Theory on data processing and instrumentation. [remote sensing
NASA Technical Reports Server (NTRS)
Billingsley, F. C.
1978-01-01
A selection of NASA Earth observations programs are reviewed, emphasizing hardware capabilities. Sampling theory, noise and detection considerations, and image evaluation are discussed for remote sensor imagery. Vision and perception are considered, leading to numerical image processing. The use of multispectral scanners and of multispectral data processing systems, including digital image processing, is depicted. Multispectral sensing and analysis in application with land use and geographical data systems are also covered.
NASA Technical Reports Server (NTRS)
Deckert, George
2010-01-01
This viewgraph presentation reviews The NASA Hazard Analysis process. The contents include: 1) Significant Incidents and Close Calls in Human Spaceflight; 2) Subsystem Safety Engineering Through the Project Life Cycle; 3) The Risk Informed Design Process; 4) Types of NASA Hazard Analysis; 5) Preliminary Hazard Analysis (PHA); 6) Hazard Analysis Process; 7) Identify Hazardous Conditions; 8) Consider All Interfaces; 9) Work a Preliminary Hazard List; 10) NASA Generic Hazards List; and 11) Final Thoughts
Some Computer-Based Developments in Sociology.
ERIC Educational Resources Information Center
Heise, David R.; Simmons, Roberta G.
1985-01-01
Discusses several ways in which computers are being used in sociology and how they continue to change this discipline. Areas considered include data collection, data analysis, simulations of social processes based on mathematical models, and problem areas (including standardization concerns, training, and the financing of computing facilities).…
Solving Tommy's Writing Problems.
ERIC Educational Resources Information Center
Burdman, Debra
1986-01-01
The article describes an approach by which word processing helps to solve some of the writing problems of learning disabled students. Aspects considered include prewriting, drafting, revising, and completing the story. (CL)
Renewal and change for health care executives.
Burke, G C; Bice, M O
1991-01-01
Health care executives must consider renewal and change within their own lives if they are to breathe life into their own institutions. Yet numerous barriers to executive renewal exist, including time pressures, fatigue, cultural factors, and trustee attitudes. This essay discusses such barriers and suggests approaches that health care executives may consider for programming renewal into their careers. These include self-assessment for professional and personal goals, career or job change, process vs. outcome considerations, solitude, networking, lifelong education, surrounding oneself with change agents, business travel and sabbaticals, reading outside the field, physical exercise, mentoring, learning from failures, a sense of humor, spiritual reflection, and family and friends. Renewal is a continuous, lifelong process requiring constant learning. Individual executives would do well to develop a framework for renewal in their careers and organizations.
NASA Astrophysics Data System (ADS)
Kundisch, Dennis; Zorzi, Robin
Although theoretically necessary, social capital is not considered within the process of asset allocation for private investors. Both the lack of appropriate practical valuation concepts and the effort of providing and processing the required information as input for a valuation were obstacles to include social capital in this process. However, first theoretical financial models for the evaluation of social capital recently have become available. Moreover, the fast growth of business community websites and the technological progress in Web 2.0 tools that allow and acquire the active involvement of users, facilitate the provision and processing of valuation relevant information. In this paper we focus on the second aspect and propose a social software-based concept that allows for an integration of social capital in the asset allocation process.
Analysis of Rainfall Infiltration Law in Unsaturated Soil Slope
Zhang, Gui-rong; Qian, Ya-jun; Wang, Zhang-chun; Zhao, Bo
2014-01-01
In the study of unsaturated soil slope stability under rainfall infiltration, it is worth continuing to explore how much rainfall infiltrates into the slope in a rain process, and the amount of rainfall infiltrating into slope is the important factor influencing the stability. Therefore, rainfall infiltration capacity is an important issue of unsaturated seepage analysis for slope. On the basis of previous studies, rainfall infiltration law of unsaturated soil slope is analyzed. Considering the characteristics of slope and rainfall, the key factors affecting rainfall infiltration of slope, including hydraulic properties, water storage capacity (θ s - θ r), soil types, rainfall intensities, and antecedent and subsequent infiltration rates on unsaturated soil slope, are discussed by using theory analysis and numerical simulation technology. Based on critical factors changing, this paper presents three calculation models of rainfall infiltrability for unsaturated slope, including (1) infiltration model considering rainfall intensity; (2) effective rainfall model considering antecedent rainfall; (3) infiltration model considering comprehensive factors. Based on the technology of system response, the relationship of rainfall and infiltration is described, and the prototype of regression model of rainfall infiltration is given, in order to determine the amount of rain penetration during a rain process. PMID:24672332
Analysis of rainfall infiltration law in unsaturated soil slope.
Zhang, Gui-rong; Qian, Ya-jun; Wang, Zhang-chun; Zhao, Bo
2014-01-01
In the study of unsaturated soil slope stability under rainfall infiltration, it is worth continuing to explore how much rainfall infiltrates into the slope in a rain process, and the amount of rainfall infiltrating into slope is the important factor influencing the stability. Therefore, rainfall infiltration capacity is an important issue of unsaturated seepage analysis for slope. On the basis of previous studies, rainfall infiltration law of unsaturated soil slope is analyzed. Considering the characteristics of slope and rainfall, the key factors affecting rainfall infiltration of slope, including hydraulic properties, water storage capacity (θs - θr), soil types, rainfall intensities, and antecedent and subsequent infiltration rates on unsaturated soil slope, are discussed by using theory analysis and numerical simulation technology. Based on critical factors changing, this paper presents three calculation models of rainfall infiltrability for unsaturated slope, including (1) infiltration model considering rainfall intensity; (2) effective rainfall model considering antecedent rainfall; (3) infiltration model considering comprehensive factors. Based on the technology of system response, the relationship of rainfall and infiltration is described, and the prototype of regression model of rainfall infiltration is given, in order to determine the amount of rain penetration during a rain process.
Beyond Our Boundaries: Research and Technology
NASA Technical Reports Server (NTRS)
1996-01-01
Topics considered include: Propulsion and Fluid Management; Structures and Dynamics; Materials and Manufacturing Processes; Sensor Technology; Software Technology; Optical Systems; Microgravity Science; Earth System Science; Astrophysics; Solar Physics; and Technology Transfer.
Exploring the Contributions of School Belonging to Complete Mental Health Screening
ERIC Educational Resources Information Center
Moffa, Kathryn; Dowdy, Erin; Furlong, Michael J.
2016-01-01
Considering the many positive outcomes associated with adolescents' sense of school belonging, including psychological functioning, it is possible that including an assessment of school belonging within a complete mental health screening process could contribute to the prediction of students' future mental health status. This exploratory study…
ERIC Educational Resources Information Center
Dudley, John; Karnes, Frances A.
2011-01-01
Divorce is often a contentious process with multiple issues to decide, especially in cases in which there are children involved. Divorce raises several legal issues when considering the well-being of children, including those who are gifted. In this article, the authors discuss these issues which include school choice, child support, and custody…
14 CFR 11.71 - What information must I include in my petition for rulemaking?
Code of Federal Regulations, 2013 CFR
2013-01-01
... businesses, small organizations, small governmental jurisdictions, and Indian tribes. (3) The recordkeeping... your proposed action, including relevant technical and scientific data available to you. (6) Any... process of considering your petition, we may ask that you provide information or data available to you...
14 CFR 11.71 - What information must I include in my petition for rulemaking?
Code of Federal Regulations, 2012 CFR
2012-01-01
... businesses, small organizations, small governmental jurisdictions, and Indian tribes. (3) The recordkeeping... your proposed action, including relevant technical and scientific data available to you. (6) Any... process of considering your petition, we may ask that you provide information or data available to you...
14 CFR 11.71 - What information must I include in my petition for rulemaking?
Code of Federal Regulations, 2014 CFR
2014-01-01
... businesses, small organizations, small governmental jurisdictions, and Indian tribes. (3) The recordkeeping... your proposed action, including relevant technical and scientific data available to you. (6) Any... process of considering your petition, we may ask that you provide information or data available to you...
14 CFR 11.71 - What information must I include in my petition for rulemaking?
Code of Federal Regulations, 2011 CFR
2011-01-01
... businesses, small organizations, small governmental jurisdictions, and Indian tribes. (3) The recordkeeping... your proposed action, including relevant technical and scientific data available to you. (6) Any... process of considering your petition, we may ask that you provide information or data available to you...
The Physiology of Exercise and the Process of Aging.
ERIC Educational Resources Information Center
Mravetz, Patricia
A physical fitness plan is considered desirable for young people, young adults, and especially older adults. This program for secondary level students focuses on the physiology of exercise and the process of aging, and stresses the need for physical fitness. Specific objectives include the following: (1) to let students become evaluators of their…
College & University Budgeting. An Introduction for Faculty and Academic Administrators.
ERIC Educational Resources Information Center
Meisinger, Richard J., Jr.; Dubeck, Leroy W.
A budgeting handbook for academic administrators and faculty is presented. Economic and political influences on budgeting are considered, along with sources of funds for public and private colleges, and the chronology of the budget process. Multiyear summaries of the budget process in different types of colleges are included. Some major policy…
The Placement Handbook. A Guide for the Competitive Employment of the Handicapped.
ERIC Educational Resources Information Center
Horn, Adelaide; Drury, Stephen
This handbook stresses those components that are considered peripheral to the placement process but that must precede the actual placement. The philosophy of placement upon which this guide is based appears first. Discussions follow of the basic components of the process of training and placement of handicapped individuals, including a varied…
Chasey, K L; McKee, R H
1993-01-01
Lubricant base oils are petroleum products that are predominantly derived from the vacuum distillation of crude oil. Various types of refinement can be employed during the manufacturing process, and evidence suggests that certain of the associated process streams produce skin cancer. Polycyclic aromatic compounds (PACs), some of which are considered as the causative agents, are removed, concentrated or chemically converted during the refinement process. In order to understand the effects of various types of refinement processes on carcinogenic potential, 94 oils were evaluated in the mouse epidermal cancer bioassay. This Exxon database is unique, because of the wide range of crude oils and processing histories represented. Seven processing history classifications are described, and conclusions concerning the impacts of each refinement process on dermal carcinogenicity are discussed. This research also included an evaluation of selected biological and chemical test methods for predicting carcinogenic potential. These included a modified version of the Ames test for mutagenicity, as well as analytical characterizations of the polycyclic aromatic structures in the oils. For classification purposes, a sample was considered to be carcinogenic if it resulted in the production of two or more tumor-bearing animals (in test groups of either 40 or 50 animals). The modified Ames test was considered to be positive if the mutagenicity index was > or = 2.0, and PAC analyses were similarly designated as positive or negative according to proposed guidelines. All of the alternative test methods showed similar agreement with dermal carcinogenicity bioassay data; concordance values were > or = 80%. However, each test was incorrect in ca. 10%-20% of the cases evaluated.(ABSTRACT TRUNCATED AT 250 WORDS)
Supplier selection based on complex indicator of finished products quality
NASA Astrophysics Data System (ADS)
Chernikova, Anna; Golovkina, Svetlana; Kuzmina, Svetlana; Demenchenok, Tatiana
2017-10-01
In the article the authors consider possible directions of solving problems when selecting a supplier for deliveries of raw materials and materials of an industrial enterprise, possible difficulties are analyzed and ways of their solution are suggested. Various methods are considered to improve the efficiency of the supplier selection process based on the analysis of the paper bags supplier selection process for the needs of the construction company. In the article the calculation of generalized indicators and complex indicator, which should include single indicators, formed in groups that reflect different aspects of quality, is presented.
Gravity dependent processes and intracellular motion
NASA Technical Reports Server (NTRS)
Todd, Paul
1991-01-01
Most organelles large enough to sediment or to undergo isothermal settling within eukaryotic cells are held in position by one or more components of the cytoskeleton. The interior of eukaryotic cells is considered to be very crowded, and the evaluation of natural-convective processes is very difficult. In a most simple view, the cell may be considered as consisting of four immiscible phases among which solutes are exchanged causing steep concentration gradients and thermodynamic conditions far from equilibrium. Extracellular gravity-related forces may include natural convection due to solute gradients external to single cells or the work performed by swimming, ciliated, or elongating cells.
EOS image data processing system definition study
NASA Technical Reports Server (NTRS)
Gilbert, J.; Honikman, T.; Mcmahon, E.; Miller, E.; Pietrzak, L.; Yorsz, W.
1973-01-01
The Image Processing System (IPS) requirements and configuration are defined for NASA-sponsored advanced technology Earth Observatory System (EOS). The scope included investigation and definition of IPS operational, functional, and product requirements considering overall system constraints and interfaces (sensor, etc.) The scope also included investigation of the technical feasibility and definition of a point design reflecting system requirements. The design phase required a survey of present and projected technology related to general and special-purpose processors, high-density digital tape recorders, and image recorders.
NASA Astrophysics Data System (ADS)
Daluge, D. R.; Ruedger, W. H.
1981-06-01
Problems encountered in testing onboard signal processing hardware designed to achieve radiometric and geometric correction of satellite imaging data are considered. These include obtaining representative image and ancillary data for simulation and the transfer and storage of a large quantity of image data at very high speed. The high resolution, high speed preprocessing of LANDSAT-D imagery is considered.
Planetary Protection Considerations for Life Support and Habitation Systems
NASA Technical Reports Server (NTRS)
Barta, Daniel J.; Hogan, John A.
2010-01-01
Life support systems for future human missions beyond low Earth orbit may include a combination of existing hardware components and advanced technologies. Discipline areas for technology development include atmosphere revitalization, water recovery, solid waste management, crew accommodations, food production, thermal systems, environmental monitoring, fire protection and radiation protection. Life support systems will be influenced by in situ resource utilization (ISRU), crew mobility and the degree of extravehicular activity. Planetary protection represents an additional set of requirements that technology developers have generally not considered. Planetary protection guidelines will affect the kind of operations, processes, and functions that can take place during future exploration missions, including venting and discharge of liquids and solids, ejection of wastes, use of ISRU, requirements for cabin atmospheric trace contaminant concentrations, cabin leakage and restrictions on what materials, organisms, and technologies that may be brought on missions. Compliance with planetary protection requirements may drive development of new capabilities or processes (e.g. in situ sterilization, waste containment, contaminant measurement) and limit or prohibit certain kinds of operations or processes (e.g. unfiltered venting). Ultimately, there will be an effect on mission costs, including the mission trade space. Planetary protection requirements need to be considered early in technology development programs. It is expected that planetary protection will have a major impact on technology selection for future missions.
Representation of dissolved organic carbon in the JULES land surface model (vn4.4_JULES-DOCM)
NASA Astrophysics Data System (ADS)
Nakhavali, Mahdi; Friedlingstein, Pierre; Lauerwald, Ronny; Tang, Jing; Chadburn, Sarah; Camino-Serrano, Marta; Guenet, Bertrand; Harper, Anna; Walmsley, David; Peichl, Matthias; Gielen, Bert
2018-02-01
Current global models of the carbon (C) cycle consider only vertical gas exchanges between terrestrial or oceanic reservoirs and the atmosphere, thus not considering the lateral transport of carbon from the continents to the oceans. Therefore, those models implicitly consider all of the C which is not respired to the atmosphere to be stored on land and hence overestimate the land C sink capability. A model that represents the whole continuum from atmosphere to land and into the ocean would provide a better understanding of the Earth's C cycle and hence more reliable historical or future projections. A first and critical step in that direction is to include processes representing the production and export of dissolved organic carbon in soils. Here we present an original representation of dissolved organic C (DOC) processes in the Joint UK Land Environment Simulator (JULES-DOCM) that integrates a representation of DOC production in terrestrial ecosystems based on the incomplete decomposition of organic matter, DOC decomposition within the soil column, and DOC export to the river network via leaching. The model performance is evaluated in five specific sites for which observations of soil DOC concentration are available. Results show that the model is able to reproduce the DOC concentration and controlling processes, including leaching to the riverine system, which is fundamental for integrating terrestrial and aquatic ecosystems. Future work should include the fate of exported DOC in the river system as well as DIC and POC export from soil.
Thinking through cancer risk: characterizing smokers' process of risk determination.
Hay, Jennifer; Shuk, Elyse; Cruz, Gustavo; Ostroff, Jamie
2005-10-01
The perception of cancer risk motivates cancer risk reduction behaviors. However, common measurement strategies for cancer risk perceptions, which involve numerical likelihood estimates, do not adequately capture individuals' thoughts and feelings about cancer risk. To guide the development of novel measurement strategies, the authors used semistructured interviews to examine the thought processes used by smokers (N = 15) as they considered their cancer risk. They used grounded theory to guide systematic data coding and develop a heuristic model describing smokers' risk perception process that includes a cognitive, primarily rational process whereby salient personal risk factors for cancer are considered and combined, and an affective/attitudinal process, which shifts risk perceptions either up or down. The model provides a tentative explanation concerning how people hold cancer risk perceptions that diverge from rational assessment of their risks and will be useful in guiding the development of non-numerical measurements strategies for cancer risk perceptions.
DOE Office of Scientific and Technical Information (OSTI.GOV)
NONE
Thunder Energy Inc. received approval from the Alberta Energy and Utilities Board for modification of an existing gas plant to process sour gas, and also applied for permission to increase the hydrogen sulfide content of its existing pipelines in the Kelsey area. This report presents the views of Thunder Energy, the Board, and various intervenors at a hearing held to consider objections to the plant approval and matters related to the application. Issues considered include the need for sour gas processing, the need for the plant modification as opposed to the feasibility of using existing sour gas processing facilities, environmentalmore » impacts, and the requirements for notification of industry in the area. The report concludes with the Board`s decision.« less
Improvement of the System of Training of Specialists by University for Coal Mining Enterprises
NASA Astrophysics Data System (ADS)
Mikhalchenko, Vadim; Seredkina, Irina
2017-11-01
In the article the ingenious technique of the Quality Function Deployment with reference to the process of training of specialists with higher education by university is considered. The method is based on the step-by-step conversion of customer requirements into specific organizational, meaningful and functional transformations of the technological process of the university. A fully deployed quality function includes four stages of tracking customer requirements while creating a product: product planning and design, process design, production design. The Quality Function Deployment can be considered as one of the methods for optimizing the technological processes of training of specialists with higher education in the current economic conditions. Implemented at the initial stages of the life cycle of the technological process, it ensures not only the high quality of the "product" of graduate school, but also the fullest possible satisfaction of consumer's requests and expectations.
Process Definition and Modeling Guidebook. Version 01.00.02
1992-12-01
material (and throughout the guidebook)process defnition is considered to be the act of representing the important characteristics of a process in a...characterized by software standards and guidelines, software inspections and reviews, and more formalized testing (including test plans, test sup- port tools...paper-based approach works well for training, examples, and possibly even small pilot projects and case studies. However, large projects will benefit from
Cogeneration Technology Alternatives Study (CTAS). Volume 1: Summary report
NASA Technical Reports Server (NTRS)
Gerlaugh, H. E.; Hall, E. W.; Brown, D. H.; Priestley, R. R.; Knightly, W. F.
1980-01-01
Large savings can be made in industry by cogenerating electric power and process heat in single energy conversion systems rather than separately in utility plants and in process boilers. About fifty industrial processes from the largest energy consuming sectors were used as a basis for matching a similar number of energy conversion systems that are considered as candidates which can be made available by the 1985 to 2000 time period. The sectors considered included food, textiles, lumber, paper, chemicals, petroleum, glass, and primary metals. The energy conversion systems included steam and gas turbines, diesels, thermionics, stirling, closed-cycle and steam injected gas turbines, and fuel cells. Fuels considered were coal, both coal and petroleum-based residual and distillate liquid fuels, and low Btu gas obtained through the on-site gasification of coal. An attempt was made to use consistent assumptions and a consistent set of ground rules for determining performance and cost in individual plants and on a national level. It was found that: (1) atmospheric and pressurized fluidized bed steam turbine systems were the most attractive of the direct coal-fired systems; and (2) open-cycle gas turbines with heat recovery steam generators and combined-cycles with NO(x) emission reduction and moderately increased firing temperatures were the most attractive of the coal-derived liquid-fired systems.
A general model for attitude determination error analysis
NASA Technical Reports Server (NTRS)
Markley, F. Landis; Seidewitz, ED; Nicholson, Mark
1988-01-01
An overview is given of a comprehensive approach to filter and dynamics modeling for attitude determination error analysis. The models presented include both batch least-squares and sequential attitude estimation processes for both spin-stabilized and three-axis stabilized spacecraft. The discussion includes a brief description of a dynamics model of strapdown gyros, but it does not cover other sensor models. Model parameters can be chosen to be solve-for parameters, which are assumed to be estimated as part of the determination process, or consider parameters, which are assumed to have errors but not to be estimated. The only restriction on this choice is that the time evolution of the consider parameters must not depend on any of the solve-for parameters. The result of an error analysis is an indication of the contributions of the various error sources to the uncertainties in the determination of the spacecraft solve-for parameters. The model presented gives the uncertainty due to errors in the a priori estimates of the solve-for parameters, the uncertainty due to measurement noise, the uncertainty due to dynamic noise (also known as process noise or measurement noise), the uncertainty due to the consider parameters, and the overall uncertainty due to all these sources of error.
Progressing to University: Hidden Messages at Two State Schools
ERIC Educational Resources Information Center
Donnelly, Michael
2015-01-01
This paper considers some of the ways that schools play a role in shaping higher education (HE) decision-making. Through their everyday practices and processes, schools can carry hidden messages about progression to HE, including choice of university. The sorts of routine aspects of school life dealt with here include events and activities,…
ERIC Educational Resources Information Center
Zholdasbekova, S.; Karataev, G.; Yskak, A.; Zholdasbekov, A.; Nurzhanbaeva, J.
2015-01-01
This article describes the major components of required technological skills (TS) for future designers taught during the academic process of a college. It considers the choices in terms of the various logical operations required by the fashion industry including fabric processing, assembly charts, performing work operations, etc. The article…
Candidate space processing techniques for biomaterials other than preparative electrophoresis
NASA Technical Reports Server (NTRS)
Brooks, D. E.
1976-01-01
The advantages of performing the partition and countercurrent distribution (CCD) of cells in phase separated aqueous polymer systems under reduced gravity were assessed. Other possible applications considered for the space processing program include the freezing front separation of cells, adsorption of cells at the air-water interface, and the macrophage electrophoretic mobility test for cancer.
43 CFR 2804.21 - What other factors will BLM consider in determining processing and monitoring fees?
Code of Federal Regulations, 2012 CFR
2012-10-01
... Relating to Public Lands (Continued) BUREAU OF LAND MANAGEMENT, DEPARTMENT OF THE INTERIOR LAND RESOURCE MANAGEMENT (2000) RIGHTS-OF-WAY UNDER THE FEDERAL LAND POLICY MANAGEMENT ACT Applying for FLPMA Grants § 2804... factors. If you include this information in your application, in arriving at your processing or monitoring...
43 CFR 2804.21 - What other factors will BLM consider in determining processing and monitoring fees?
Code of Federal Regulations, 2013 CFR
2013-10-01
... Relating to Public Lands (Continued) BUREAU OF LAND MANAGEMENT, DEPARTMENT OF THE INTERIOR LAND RESOURCE MANAGEMENT (2000) RIGHTS-OF-WAY UNDER THE FEDERAL LAND POLICY MANAGEMENT ACT Applying for FLPMA Grants § 2804... factors. If you include this information in your application, in arriving at your processing or monitoring...
43 CFR 2804.21 - What other factors will BLM consider in determining processing and monitoring fees?
Code of Federal Regulations, 2014 CFR
2014-10-01
... Relating to Public Lands (Continued) BUREAU OF LAND MANAGEMENT, DEPARTMENT OF THE INTERIOR LAND RESOURCE MANAGEMENT (2000) RIGHTS-OF-WAY UNDER THE FEDERAL LAND POLICY MANAGEMENT ACT Applying for FLPMA Grants § 2804... factors. If you include this information in your application, in arriving at your processing or monitoring...
43 CFR 2804.21 - What other factors will BLM consider in determining processing and monitoring fees?
Code of Federal Regulations, 2011 CFR
2011-10-01
... Relating to Public Lands (Continued) BUREAU OF LAND MANAGEMENT, DEPARTMENT OF THE INTERIOR LAND RESOURCE MANAGEMENT (2000) RIGHTS-OF-WAY UNDER THE FEDERAL LAND POLICY MANAGEMENT ACT Applying for FLPMA Grants § 2804... factors. If you include this information in your application, in arriving at your processing or monitoring...
The use of biologically active filtration to oxidize ammonia as a full-scale drinking water treatment process has not been thoroughly considered in the United States. A number of concerns with biological water treatment exist including the potential release of excessive numbers o...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-10-07
... Broadcasting Services; Alamo, GA; Alton, MO; Boscobel, WI; Buffalo, OK; Cove, AR; Clayton, LA; Daisy, AR; Ennis... competitive bidding process, and are considered unsold permits that were included in Auction 91. Interested... competitive bidding process. DATES: Comments must be filed on or before October 31, 2011, and reply comments...
It Comes from the People: Community Development and Local Theology.
ERIC Educational Resources Information Center
Hinsdale, Mary Ann; And Others
The closing of local mines and factories collapsed the economic and social structure of Ivanhoe, Virginia, a small rural town once considered a dying community. This book is a case study that tells how the people of Ivanhoe organized to revitalize their town. It documents the community development process--a process that included hard work, a…
ERIC Educational Resources Information Center
Harper, Shannon; Maskaly, Jon; Kirkner, Anne; Lorenz, Katherine
2017-01-01
Title IX prohibits sex discrimination--including sexual assault--in higher education. The Department of Education Office for Civil Rights' 2011 "Dear Colleague Letter" outlines recommendations for campus sexual assault adjudication allowing a variety of procedures that fail to protect accused students' due process rights and victims'…
Trends in Process Analytical Technology: Present State in Bioprocessing.
Jenzsch, Marco; Bell, Christian; Buziol, Stefan; Kepert, Felix; Wegele, Harald; Hakemeyer, Christian
2017-08-04
Process analytical technology (PAT), the regulatory initiative for incorporating quality in pharmaceutical manufacturing, is an area of intense research and interest. If PAT is effectively applied to bioprocesses, this can increase process understanding and control, and mitigate the risk from substandard drug products to both manufacturer and patient. To optimize the benefits of PAT, the entire PAT framework must be considered and each elements of PAT must be carefully selected, including sensor and analytical technology, data analysis techniques, control strategies and algorithms, and process optimization routines. This chapter discusses the current state of PAT in the biopharmaceutical industry, including several case studies demonstrating the degree of maturity of various PAT tools. Graphical Abstract Hierarchy of QbD components.
Baillet, Athan; Gossec, Laure; Carmona, Loreto; Wit, Maarten de; van Eijk-Hustings, Yvonne; Bertheussen, Heidi; Alison, Kent; Toft, Mette; Kouloumas, Marios; Ferreira, Ricardo J O; Oliver, Susan; Rubbert-Roth, Andrea; van Assen, Sander; Dixon, William G; Finckh, Axel; Zink, Angela; Kremer, Joel; Kvien, Tore K; Nurmohamed, Michael; van der Heijde, Desirée; Dougados, Maxime
2016-06-01
In chronic inflammatory rheumatic diseases, comorbidities such as cardiovascular diseases and infections are suboptimally prevented, screened for and managed. The objective of this European League Against Rheumatism (EULAR) initiative was to propose points to consider to collect comorbidities in patients with chronic inflammatory rheumatic diseases. We also aimed to develop a pragmatic reporting form to foster the implementation of the points to consider. In accordance with the EULAR Standardised Operating Procedures, the process comprised (1) a systematic literature review of existing recommendations on reporting, screening for or preventing six selected comorbidities: ischaemic cardiovascular diseases, malignancies, infections, gastrointestinal diseases, osteoporosis and depression and (2) a consensus process involving 21 experts (ie, rheumatologists, patients, health professionals). Recommendations on how to treat the comorbidities were not included in the document as they vary across countries. The literature review retrieved 42 articles, most of which were recommendations for reporting or screening for comorbidities in the general population. The consensus process led to three overarching principles and 15 points to consider, related to the six comorbidities, with three sections: (1) reporting (ie, occurrence of the comorbidity and current treatments); (2) screening for disease (eg, mammography) or for risk factors (eg, smoking) and (3) prevention (eg, vaccination). A reporting form (93 questions) corresponding to a practical application of the points to consider was developed. Using an evidence-based approach followed by expert consensus, this EULAR initiative aims to improve the reporting and prevention of comorbidities in chronic inflammatory rheumatic diseases. Next steps include dissemination and implementation. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/
A methodology to evaluate unplanned proposed transportation projects.
DOT National Transportation Integrated Search
2008-01-01
The Virginia Department of Transportation may be asked to consider proposed transportation projects that have not originated within the transportation planning process. Examples include offers by the private sector to build infrastructure in exchange...
Lasers: A Valuable Tool for Chemists.
ERIC Educational Resources Information Center
Findsen, E. W.; Ondrias, M. R.
1986-01-01
Discusses the properties of laser light, reviews types of lasers, presents operating principles, and considers mechanical aspects of laser light production. Applications reviewed include spectroscopy, photochemical reaction initiation, and investigation of biological processes involving porphyrins. (JM)
ERIC Educational Resources Information Center
Garbe, Edward
1998-01-01
Discusses enhancing a college's competitive position by offering technological capabilities to its students, including the planning process and wiring installation issues to be considered. Highlights two examples concerning building the wiring infrastructure to support multipurpose, technology-rich learning environments. (GR)
Cameras for semiconductor process control
NASA Technical Reports Server (NTRS)
Porter, W. A.; Parker, D. L.
1977-01-01
The application of X-ray topography to semiconductor process control is described, considering the novel features of the high speed camera and the difficulties associated with this technique. The most significant results on the effects of material defects on device performance are presented, including results obtained using wafers processed entirely within this institute. Defects were identified using the X-ray camera and correlations made with probe data. Also included are temperature dependent effects of material defects. Recent applications and improvements of X-ray topographs of silicon-on-sapphire and gallium arsenide are presented with a description of a real time TV system prototype and of the most recent vacuum chuck design. Discussion is included of our promotion of the use of the camera by various semiconductor manufacturers.
Optimization in the systems engineering process
NASA Technical Reports Server (NTRS)
Lemmerman, L. A.
1984-01-01
The objective is to look at optimization as it applies to the design process at a large aircraft company. The design process at Lockheed-Georgia is described. Some examples of the impact that optimization has had on that process are given, and then some areas that must be considered if optimization is to be successful and supportive in the total design process are indicated. Optimization must continue to be sold and this selling is best done by consistent good performance. For this good performance to occur, the future approaches must be clearly thought out so that the optimization methods solve the problems that actually occur during design. The visibility of the design process must be maintained as further developments are proposed. Careful attention must be given to the management of data in the optimization process, both for technical reasons and for administrative purposes. Finally, to satisfy program needs, provisions must be included to supply data to support program decisions, and to communicate with design processes outside of the optimization process. If designers fail to adequately consider all of these needs, the future acceptance of optimization will be impeded.
Evaluation and purchase of an analytical flow cytometer: some of the numerous factors to consider.
Zucker, Robert M; Fisher, Nancy C
2013-01-01
When purchasing a flow cytometer, the decision of which brand, model, specifications, and accessories may be challenging. The decisions should initially be guided by the specific applications intended for the instrument. However, many other factors need to be considered, which include hardware, software, quality assurance, support, service, and price and recommendations from colleagues. These issues are discussed to help guide the purchasing process.
NASA Technical Reports Server (NTRS)
Daluge, D. R.; Ruedger, W. H.
1981-01-01
Problems encountered in testing onboard signal processing hardware designed to achieve radiometric and geometric correction of satellite imaging data are considered. These include obtaining representative image and ancillary data for simulation and the transfer and storage of a large quantity of image data at very high speed. The high resolution, high speed preprocessing of LANDSAT-D imagery is considered.
A multi-scale metrics approach to forest fragmentation for Strategic Environmental Impact Assessment
DOE Office of Scientific and Technical Information (OSTI.GOV)
Kim, Eunyoung, E-mail: eykim@kei.re.kr; Song, Wonkyong, E-mail: wksong79@gmail.com; Lee, Dongkun, E-mail: dklee7@snu.ac.kr
Forests are becoming severely fragmented as a result of land development. South Korea has responded to changing community concerns about environmental issues. The nation has developed and is extending a broad range of tools for use in environmental management. Although legally mandated environmental compliance requirements in South Korea have been implemented to predict and evaluate the impacts of land-development projects, these legal instruments are often insufficient to assess the subsequent impact of development on the surrounding forests. It is especially difficult to examine impacts on multiple (e.g., regional and local) scales in detail. Forest configuration and size, including forest fragmentationmore » by land development, are considered on a regional scale. Moreover, forest structure and composition, including biodiversity, are considered on a local scale in the Environmental Impact Assessment process. Recently, the government amended the Environmental Impact Assessment Act, including the SEA, EIA, and small-scale EIA, to require an integrated approach. Therefore, the purpose of this study was to establish an impact assessment system that minimizes the impacts of land development using an approach that is integrated across multiple scales. This study focused on forest fragmentation due to residential development and road construction sites in selected Congestion Restraint Zones (CRZs) in the Greater Seoul Area of South Korea. Based on a review of multiple-scale impacts, this paper integrates models that assess the impacts of land development on forest ecosystems. The applicability of the integrated model for assessing impacts on forest ecosystems through the SEIA process is considered. On a regional scale, it is possible to evaluate the location and size of a land-development project by considering aspects of forest fragmentation, such as the stability of the forest structure and the degree of fragmentation. On a local scale, land-development projects should consider the distances at which impacts occur in the vicinity of the forest ecosystem, and these considerations should include the impacts on forest vegetation and bird species. Impacts can be mitigated by considering the distances at which these influences occur. In particular, this paper presents an integrated environmental impact assessment system to be applied in the SEIA process. The integrated assessment system permits the assessment of the cumulative impacts of land development on multiple scales. -- Highlights: • The model is to assess the impact of forest fragmentation across multiple scales. • The paper suggests the type of forest fragmentation on a regional scale. • The type can be used to evaluate the location and size of a land development. • The paper shows the influence distance of land development on a local scale. • The distance can be used to mitigate the impact at an EIA process.« less
Crystallization processes in pharmaceutical technology and drug delivery design
NASA Astrophysics Data System (ADS)
Shekunov, B. Yu; York, P.
2000-04-01
Crystallization is a major technological process for particle formation in pharmaceutical industry and, in addition, plays an important role in defining the stability and drug release properties of the final dosage forms. Industrial and regulatory aspects of crystallization are briefly reviewed with reference to solid-state properties of pharmaceuticals. Crystallization, incorporating wider definition to include precipitation and solid-state transitions, is considered in terms of preparation of materials for direct compression, formation of amorphous, solvated and polymorphic forms, chiral separation of drugs, production of materials for inhalation drug delivery and injections. Finally, recent developments in supercritical fluid particle technology is considered in relationship to the areas discussed.
NASA Technical Reports Server (NTRS)
1973-01-01
The findings and recommendations of the Materials Processing and Space Manufacturing group of the space shuttle payload planning activity are presented. The effects of weightlessness on the levitation processes, mixture stability, and control over heat and mass transport in fluids are considered for investigation. The research and development projects include: (1) metallurgical processes, (2) electronic materials, (3) biological applications, and (4)nonmetallic materials and processes. Additional recommendations are provided concerning the allocation of payload space, acceptance of experiments for flight, flight qualification, and private use of the space shuttle.
Special experimental project (SEP-14) alternate surfacing bidding [summary].
DOT National Transportation Integrated Search
2008-01-01
The Kansas Department of Transportation (KDOT) has a pavement type selection process that includes the comparison of initial and life cycle costs for different pavement types. Those cost differences and secondary factors are considered when selecting...
Code of Federal Regulations, 2013 CFR
2013-07-01
... program management processes during applicable contingency operations. (2) Comply with applicable U.S..., “Policy and Procedures for Determining Workforce Mix.” (4) Fully consider, plan for, integrate, and execute acquisition of, contracted support, including synchronizing and integrating contracted support...
Code of Federal Regulations, 2012 CFR
2012-07-01
... program management processes during applicable contingency operations. (2) Comply with applicable U.S..., “Policy and Procedures for Determining Workforce Mix.” (4) Fully consider, plan for, integrate, and execute acquisition of, contracted support, including synchronizing and integrating contracted support...
Code of Federal Regulations, 2014 CFR
2014-07-01
... program management processes during applicable contingency operations. (2) Comply with applicable U.S..., “Policy and Procedures for Determining Workforce Mix.” (4) Fully consider, plan for, integrate, and execute acquisition of, contracted support, including synchronizing and integrating contracted support...
Turbulent solutions of equations of fluid motion
NASA Technical Reports Server (NTRS)
Deissler, R. G.
1985-01-01
Some turbulent solutions of the unaveraged Navier-Stokes equations (equations of fluid motion) are reviewed. Those equations are solved numerically in order to study the nonlinear physics of incompressible turbulent flow. The three components of the mean-square velocity fluctuations are initially equal for the conditions chosen. The resulting solutions show characteristics of turbulence, such as the linear and nonlinear excitation of small-scale fluctuations. For the stronger fluctuations the initially nonrandom flow develops into an apparently random turbulence. The cases considered include turbulence that is statistically homogeneous or inhomogeneous and isotropic or anisotropic. A statistically steady-state turbulence is obtained by using a spatially periodic body force. Various turbulence processes, including the transfer of energy between eddy sizes and between directional components and the production, dissipation, and spatial diffusion of turbulence, are considered. It is concluded that the physical processes occurring in turbulence can be profitably studied numerically.
NASA Technical Reports Server (NTRS)
1975-01-01
The data processing and transfer technology areas that need to be developed and that could benefit from space flight experiments are identified. Factors considered include: user requirements, concepts in 'Outlook for Space', and cost reduction. Major program thrusts formulated are an increase in end-to-end information handling and a reduction in life cycle costs.
ERIC Educational Resources Information Center
Lester, Pamela Denise
2017-01-01
A qualitative method of research was chosen for this study. This ethnographic case study examined school psychologists' and the referral process for special education services. The participants included school psychologists in a specific county in the state of Maryland. School psychologists are considered crucial members of an Individualized…
ERIC Educational Resources Information Center
Chambers, Gail S.
The regulation of the college merger process in New York, including its effects on a recent merger between private institutions, is examined. New York's higher education policy formation process and the laws and policies that make college mergers possible are considered. The merger of Eisenhower College and Rochester Institute of Technology…
Proceedings of the international conference on cybernetics and societ
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
1985-01-01
This book presents the papers given at a conference on artificial intelligence, expert systems and knowledge bases. Topics considered at the conference included automating expert system development, modeling expert systems, causal maps, data covariances, robot vision, image processing, multiprocessors, parallel processing, VLSI structures, man-machine systems, human factors engineering, cognitive decision analysis, natural language, computerized control systems, and cybernetics.
ERIC Educational Resources Information Center
Rose, Amanda J.; Rudolph, Karen D.
2006-01-01
Theory and research on sex differences in adjustment focus largely on parental, societal, and biological influences. However, it also is important to consider how peers contribute to girls' and boys' development. This article provides a critical review of sex differences in several peer relationship processes, including behavioral and…
Working group organizational meeting
NASA Technical Reports Server (NTRS)
1982-01-01
Scene radiation and atmospheric effects, mathematical pattern recognition and image analysis, information evaluation and utilization, and electromagnetic measurements and signal handling are considered. Research issues in sensors and signals, including radar (SAR) reflectometry, SAR processing speed, registration, including overlay of SAR and optical imagery, entire system radiance calibration, and lack of requirements for both sensors and systems, etc. were discussed.
Precision laser processing for micro electronics and fiber optic manufacturing
NASA Astrophysics Data System (ADS)
Webb, Andrew; Osborne, Mike; Foster-Turner, Gideon; Dinkel, Duane W.
2008-02-01
The application of laser based materials processing for precision micro scale manufacturing in the electronics and fiber optic industry is becoming increasingly widespread and accepted. This presentation will review latest laser technologies available and discuss the issues to be considered in choosing the most appropriate laser and processing parameters. High repetition rate, short duration pulsed lasers have improved rapidly in recent years in terms of both performance and reliability enabling flexible, cost effective processing of many material types including metal, silicon, plastic, ceramic and glass. Demonstrating the relevance of laser micromachining, application examples where laser processing is in use for production will be presented, including miniaturization of surface mount capacitors by applying a laser technique for demetalization of tracks in the capacitor manufacturing process and high quality laser machining of fiber optics including stripping, cleaving and lensing, resulting in optical quality finishes without the need for traditional polishing. Applications include telecoms, biomedical and sensing. OpTek Systems was formed in 2000 and provide fully integrated systems and sub contract services for laser processes. They are headquartered in the UK and are establishing a presence in North America through a laser processing facility in South Carolina and sales office in the North East.
Application of remote sensors in coastal zone observations
NASA Technical Reports Server (NTRS)
Caillat, J. M.; Elachi, C.; Brown, W. E., Jr.
1975-01-01
A review of processes taking place along coastlines and their biological consideration led to the determination of the elements which are required in the study of coastal structures and which are needed for better utilization of the resources from the oceans. The processes considered include waves, currents, and their influence on the erosion of coastal structures. Biological considerations include coastal fisheries, estuaries, and tidal marshes. Various remote sensors were analyzed for the information which they can provide and sites were proposed where a general ocean-observation plan could be tested.
When and where does preferential flow matter - from observation to large scale modelling
NASA Astrophysics Data System (ADS)
Weiler, Markus; Leistert, Hannes; Steinbrich, Andreas
2017-04-01
Preferential flow can be of relevance in a wide range of soils and the interaction of different processes and factors are still difficult to assess. As most studies (including our own studies) focusing on the effect of preferential flow are based on relatively high precipitation rates, there is always the question how relevant preferential flow is under natural conditions, considering the site specific precipitation characteristics, the effect of the drying and wetting cycle on the initial soil water condition and shrinkage cracks, the site specific soil properties, soil structure and rock fragments, and the effect of plant roots and soil fauna (e.g. earthworm channels). In order to assess this question, we developed the distributed, process-based model RoGeR (Runoff Generation Research) to include a large number relevant features and processes of preferential flow in soils. The model was developed from a large number of process based research and experiments and includes preferential flow in roots, earthworm channels, along rock fragments and shrinkage cracks. We parameterized the uncalibrated model at a high spatial resolution of 5x5m for the whole state of Baden-Württemberg in Germany using LiDAR data, degree of sealing, landuse, soil properties and geology. As the model is an event based model, we derived typical event based precipitation characteristics based on rainfall duration, mean intensity and amount. Using the site-specific variability of initial soil moisture derived from a water balance model based on the same dataset, we simulated the infiltration and recharge amounts of all event classes derived from the event precipitation characteristics and initial soil moisture conditions. The analysis of the simulation results allowed us to extracts the relevance of preferential flow for infiltration and recharge considering all factors above. We could clearly see a strong effect of the soil properties and land-use, but also, particular for clay rich soils a strong effect of the initial conditions due to the development of soil cracks. Not too surprisingly, the relevance of preferential flow was much lower when considering the whole range of precipitation events as only considering events with a high rainfall intensity. Also, the influence on infiltration and recharge were different. Despite the model can still be improved in particular considering more realistic information about the spatial and temporal variability of preferential flow by soil fauna and plants, the model already shows under what situation we need to be very careful when predicting infiltration and recharge with models considering only longer time steps (daily) or only matrix flow.
Pottie, Kevin; Welch, Vivian; Morton, Rachael; Akl, Elie A; Eslava-Schmalbach, Javier H; Katikireddi, Vittal; Singh, Jasvinder; Moja, Lorenzo; Lang, Eddy; Magrini, Nicola; Thabane, Lehana; Stanev, Roger; Matovinovic, Elizabeth; Snellman, Alexandra; Briel, Matthias; Shea, Beverly; Tugwell, Peter; Schunemann, Holger; Guyatt, Gordon; Alonso-Coello, Pablo
2017-10-01
The aim of this paper is to provide detailed guidance on how to incorporate health equity within the GRADE (Grading Recommendations Assessment and Development Evidence) evidence to decision process. We developed this guidance based on the GRADE evidence to decision framework, iteratively reviewing and modifying draft documents, in person discussion of project group members and input from other GRADE members. Considering the impact on health equity may be required, both in general guidelines and guidelines that focus on disadvantaged populations. We suggest two approaches to incorporate equity considerations: (1) assessing the potential impact of interventions on equity and (2) incorporating equity considerations when judging or weighing each of the evidence to decision criteria. We provide guidance and include illustrative examples. Guideline panels should consider the impact of recommendations on health equity with attention to remote and underserviced settings and disadvantaged populations. Guideline panels may wish to incorporate equity judgments across the evidence to decision framework. This is the fourth and final paper in a series about considering equity in the GRADE guideline development process. This series is coming from the GRADE equity subgroup. Copyright © 2017 Elsevier Inc. All rights reserved.
IDC Re-Engineering Phase 2 System Requirements Document Version 1.4
DOE Office of Scientific and Technical Information (OSTI.GOV)
Harris, James M.; Burns, John F.; Satpathi, Meara Allena
This System Requirements Document (SRD) defines waveform data processing requirements for the International Data Centre (IDC) of the Comprehensive Nuclear Test Ban Treaty Organization (CTBTO). The IDC applies, on a routine basis, automatic processing methods and interactive analysis to raw International Monitoring System (IMS) data in order to produce, archive, and distribute standard IDC products on behalf of all States Parties. The routine processing includes characterization of events with the objective of screening out events considered to be consistent with natural phenomena or non-nuclear, man-made phenomena. This document does not address requirements concerning acquisition, processing and analysis of radionuclide data,more » but includes requirements for the dissemination of radionuclide data and products.« less
IDC Re-Engineering Phase 2 System Requirements Document V1.3.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Harris, James M.; Burns, John F.; Satpathi, Meara Allena
2015-12-01
This System Requirements Document (SRD) defines waveform data processing requirements for the International Data Centre (IDC) of the Comprehensive Nuclear Test Ban Treaty Organization (CTBTO). The IDC applies, on a routine basis, automatic processing methods and interactive analysis to raw International Monitoring System (IMS) data in order to produce, archive, and distribute standard IDC products on behalf of all States Parties. The routine processing includes characterization of events with the objective of screening out events considered to be consistent with natural phenomena or non-nuclear, man-made phenomena. This document does not address requirements concerning acquisition, processing and analysis of radionuclide datamore » but includes requirements for the dissemination of radionuclide data and products.« less
[Ecological security of wastewater treatment processes: a review].
Yang, Sai; Hua, Tao
2013-05-01
Though the regular indicators of wastewater after treatment can meet the discharge requirements and reuse standards, it doesn't mean the effluent is harmless. From the sustainable point of view, to ensure the ecological and human security, comprehensive toxicity should be considered when discharge standards are set up. In order to improve the ecological security of wastewater treatment processes, toxicity reduction should be considered when selecting and optimizing the treatment processes. This paper reviewed the researches on the ecological security of wastewater treatment processes, with the focus on the purposes of various treatment processes, including the processes for special wastewater treatment, wastewater reuse, and for the safety of receiving waters. Conventional biological treatment combined with advanced oxidation technologies can enhance the toxicity reduction on the base of pollutants removal, which is worthy of further study. For the process aimed at wastewater reuse, the integration of different process units can complement the advantages of both conventional pollutants removal and toxicity reduction. For the process aimed at ecological security of receiving waters, the emphasis should be put on the toxicity reduction optimization of process parameters and process unit selection. Some suggestions for the problems in the current research and future research directions were put forward.
Review--Interactions between diatoms and stainless steel: focus on biofouling and biocorrosion.
Landoulsi, J; Cooksey, K E; Dupres, V
2011-11-01
There is a considerable body of information regarding bacterially enhanced corrosion, however, this review focuses on diatoms (unicellular algae) whose contribution to biocorrosion is less well studied. The reasons why diatoms have been neglected in studies of biocorrosion in natural waters are discussed and the question whether diatoms should be considered as inert with respect of electrochemical processes is considered. A particular focus is given to the case of stainless steels (SS), which are widely used in variety of applications in natural waters. Basic information on the cell biology of diatoms is included in the review, particularly with respect to their ability to 'sense' and adhere to surfaces. Investigations at the nanoscale are reviewed as these studies provide information about the behavior of cells at interfaces. Recent advances include the use of atomic force microscopy (AFM), although only a few studies have been applied to diatoms. Regarding the electrochemical behavior of SS, the mechanisms by which diatoms influence the potential ennoblement process is discussed. Such studies reveal the association of diatoms, in addition to bacteria, with biocorrosion processes.
Community Decadal Panel for Terrestrial Analogs to Mars
NASA Astrophysics Data System (ADS)
Barlow, N. G.; Farr, T.; Baker, V. R.; Bridges, N.; Carsey, F.; Duxbury, N.; Gilmore, M. S.; Green, J. R.; Grin, E.; Hansen, V.; Keszthelyi, L.; Lanagan, P.; Lentz, R.; Marinangeli, L.; Morris, P. A.; Ori, G. G.; Paillou, P.; Robinson, C.; Thomson, B.
2001-11-01
It is well recognized that interpretations of Mars must begin with the Earth as a reference. The most successful comparisons have focused on understanding geologic processes on the Earth well enough to extrapolate to Mars' environment. Several facets of terrestrial analog studies have been pursued and are continuing. These studies include field workshops, characterization of terrestrial analog sites for Mars, instrument tests, laboratory measurements (including analysis of martian meteorites), and computer and laboratory modeling. The combination of all these activities allows scientists to constrain the processes operating in specific terrestrial environments and extrapolate how similar processes could affect Mars. The Terrestrial Analogs for Mars Community Panel is considering the following two key questions: (1) How do terrestrial analog studies tie in to the MEPAG science questions about life, past climate, and geologic evolution of Mars, and (2) How can future instrumentation be used to address these questions. The panel is considering the issues of data collection, value of field workshops, data archiving, laboratory measurements and modeling, human exploration issues, association with other areas of solar system exploration, and education and public outreach activities.
NASA Astrophysics Data System (ADS)
Farr, T. G.; Arcone, S.; Arvidson, R. W.; Baker, V.; Barlow, N. G.; Beaty, D.; Bell, M. S.; Blankenship, D. D.; Bridges, N.; Briggs, G.; Bulmer, M.; Carsey, F.; Clifford, S. M.; Craddock, R. A.; Dickerson, P. W.; Duxbury, N.; Galford, G. L.; Garvin, J.; Grant, J.; Green, J. R.; Gregg, T. K. P.; Guinness, E.; Hansen, V. L.; Hecht, M. H.; Holt, J.; Howard, A.; Keszthelyi, L. P.; Lee, P.; Lanagan, P. D.; Lentz, R. C. F.; Leverington, D. W.; Marinangeli, L.; Moersch, J. E.; Morris-Smith, P. A.; Mouginis-Mark, P.; Olhoeft, G. R.; Ori, G. G.; Paillou, P.; Reilly, J. F., II; Rice, J. W., Jr.; Robinson, C. A.; Sheridan, M.; Snook, K.; Thomson, B. J.; Watson, K.; Williams, K.; Yoshikawa, K.
2002-08-01
It is well recognized that interpretations of Mars must begin with the Earth as a reference. The most successful comparisons have focused on understanding geologic processes on the Earth well enough to extrapolate to Mars' environment. Several facets of terrestrial analog studies have been pursued and are continuing. These studies include field workshops, characterization of terrestrial analog sites, instrument tests, laboratory measurements (including analysis of Martian meteorites), and computer and laboratory modeling. The combination of all these activities allows scientists to constrain the processes operating in specific terrestrial environments and extrapolate how similar processes could affect Mars. The Terrestrial Analogs for Mars Community Panel has considered the following two key questions: (1) How do terrestrial analog studies tie in to the Mars Exploration Payload Assessment Group science questions about life, past climate, and geologic evolution of Mars, and (2) How can future instrumentation be used to address these questions. The panel has considered the issues of data collection, value of field workshops, data archiving, laboratory measurements and modeling, human exploration issues, association with other areas of solar system exploration, and education and public outreach activities.
Reward Processing, Neuroeconomics, and Psychopathology.
Zald, David H; Treadway, Michael T
2017-05-08
Abnormal reward processing is a prominent transdiagnostic feature of psychopathology. The present review provides a framework for considering the different aspects of reward processing and their assessment, and highlights recent insights from the field of neuroeconomics that may aid in understanding these processes. Although altered reward processing in psychopathology has often been treated as a general hypo- or hyperresponsivity to reward, increasing data indicate that a comprehensive understanding of reward dysfunction requires characterization within more specific reward-processing domains, including subjective valuation, discounting, hedonics, reward anticipation and facilitation, and reinforcement learning. As such, more nuanced models of the nature of these abnormalities are needed. We describe several processing abnormalities capable of producing the types of selective alterations in reward-related behavior observed in different forms of psychopathology, including (mal)adaptive scaling and anchoring, dysfunctional weighting of reward and cost variables, competition between valuation systems, and reward prediction error signaling.
Reward Processing, Neuroeconomics, and Psychopathology
Zald, David H.; Treadway, Michael
2018-01-01
Abnormal reward processing is a prominent transdiagnostic feature of psychopathology. The present review provides a framework for considering the different aspects of reward processing and their assessment and highlight recent insights from the field of neuroeconomics that may aid in understanding these processes. Although altered reward processing in psychopathology has often been treated as a general hypo- or hyper-responsivity to reward, increasing data indicate that a comprehensive understanding of reward dysfunction requires characterization within more specific reward processing domains, including subjective valuation, discounting, hedonics, reward anticipation and facilitation, and reinforcement learning. As such, more nuanced models of the nature of these abnormalities are needed. We describe several processing abnormalities capable of producing the types of selective alterations in reward related behavior observed in different forms of psychopathology, including (mal)adaptive scaling and anchoring, dysfunctional weighting of reward and cost variables, completion between valuation systems, and positive prediction error signaling. PMID:28301764
Legal Aspects of Program Closure.
ERIC Educational Resources Information Center
Hample, Stephen R.
1982-01-01
Legal issues in program discontinuance and resulting lawsuits are considered, including liability to the faculty, students, and other constituencies; freedom of speech; due process; contractual obligations; legal defense; and consideration of program alternatives. A list of related resources is appended. (MSE)
Ecosystem Services Provided by Stream Fishes
Stream fish provide important services to people, including recreation and food, regulation of ecosystem processes, and aesthetic benefits. If the services provided by fish in different streams can be measured, then they can be valued and considered in restoration decisions. We...
ORES - Objective Referenced Evaluation in Science.
ERIC Educational Resources Information Center
Shaw, Terry
Science process skills considered important in making decisions and solving problems include: observing, classifying, measuring, using numbers, using space/time relationships, communicating, predicting, inferring, manipulating variables, making operational definitions, forming hypotheses, interpreting data, and experimenting. This 60-item test,…
Code of Federal Regulations, 2010 CFR
2010-04-01
... consider the organization's history with regard to the management of other grants, including DOL grants... fashion. (b) This responsibility review is independent of the competitive process. Applicants which are...
Addissie, Adamu; Davey, Gail; Newport, Melanie J; Addissie, Thomas; MacGregor, Hayley; Feleke, Yeweyenhareg; Farsides, Bobbie
2014-05-02
Rapid Ethical Assessment (REA) is a form of rapid ethnographic assessment conducted at the beginning of research project to guide the consent process with the objective of reconciling universal ethical guidance with specific research contexts. The current study is conducted to assess the perceived relevance of introducing REA as a mainstream tool in Ethiopia. Mixed methods research using a sequential explanatory approach was conducted from July to September 2012, including 241 cross-sectional, self-administered and 19 qualitative, in-depth interviews among health researchers and regulators including ethics committee members in Ethiopian health research institutions and universities. In their evaluation of the consent process, only 40.2% thought that the consent process and information given were adequately understood by study participants; 84.6% claimed they were not satisfied with the current consent process and 85.5% thought the best interests of study participants were not adequately considered. Commonly mentioned consent-related problems included lack of clarity (48.1%), inadequate information (34%), language barriers (28.2%), cultural differences (27.4%), undue expectations (26.6%) and power imbalances (20.7%). About 95.4% believed that consent should be contextualized to the study setting and 39.4% thought REA would be an appropriate approach to improve the perceived problems. Qualitative findings helped to further explore the gaps identified in the quantitative findings and to map-out concerns related to the current research consent process in Ethiopia. Suggestions included, conducting REA during the pre-test (pilot) phase of studies when applicable. The need for clear guidance for researchers on issues such as when and how to apply the REA tools was stressed. The study findings clearly indicated that there are perceived to be correctable gaps in the consent process of medical research in Ethiopia. REA is considered relevant by researchers and stakeholders to address these gaps. Exploring further the feasibility and applicability of REA is recommended.
2014-01-01
Background Rapid Ethical Assessment (REA) is a form of rapid ethnographic assessment conducted at the beginning of research project to guide the consent process with the objective of reconciling universal ethical guidance with specific research contexts. The current study is conducted to assess the perceived relevance of introducing REA as a mainstream tool in Ethiopia. Methods Mixed methods research using a sequential explanatory approach was conducted from July to September 2012, including 241 cross-sectional, self-administered and 19 qualitative, in-depth interviews among health researchers and regulators including ethics committee members in Ethiopian health research institutions and universities. Results In their evaluation of the consent process, only 40.2% thought that the consent process and information given were adequately understood by study participants; 84.6% claimed they were not satisfied with the current consent process and 85.5% thought the best interests of study participants were not adequately considered. Commonly mentioned consent-related problems included lack of clarity (48.1%), inadequate information (34%), language barriers (28.2%), cultural differences (27.4%), undue expectations (26.6%) and power imbalances (20.7%). About 95.4% believed that consent should be contextualized to the study setting and 39.4% thought REA would be an appropriate approach to improve the perceived problems. Qualitative findings helped to further explore the gaps identified in the quantitative findings and to map-out concerns related to the current research consent process in Ethiopia. Suggestions included, conducting REA during the pre-test (pilot) phase of studies when applicable. The need for clear guidance for researchers on issues such as when and how to apply the REA tools was stressed. Conclusion The study findings clearly indicated that there are perceived to be correctable gaps in the consent process of medical research in Ethiopia. REA is considered relevant by researchers and stakeholders to address these gaps. Exploring further the feasibility and applicability of REA is recommended. PMID:24885049
NASA Astrophysics Data System (ADS)
Rossi, M.; Torri, D.; Bacaro, G.; Mondini, A.; Reichenbach, P.; Fiorucci, F.; Marchesini, I.
2013-12-01
Fires can change significantly the characteristics of slopes. Their effect on vegetation, soil properties, and fauna can influence slope instability processes, including channeled erosion and mass movements. Even if in the literature attempts to estimate these effects were made using mostly empirical approaches, evaluating quantitatively the impact of fires on slope instability processes remain challenging. In a small basin in Central Italy, where an intense arson occurred in July 2012, we estimated the effects of fire on the hazard posed by different type of instability processes. For the purpose we modelled separately channeled erosion phenomena and rock falls, for which a significant impact of fires was expected. For the former we exploited the LANDPLANER (LANDscape, Plants, LANdslides and ERosion) model, which is able to simulate the hydrological response of a slope, and their effect on instability processes, under human-induced or natural changing scenarios, including climatic, land use, and slope morphology changes. For the latter we exploited two different modeling approaches considering directly (Rockyfor3D model) or indirectly (STONE model) the effect of the vegetation on the movement of rock masses along the slope. All the model simulations were repeated considering land use scenarios before and after the fire. Those were derived through field surveys and though the supervised classification of high resolution satellite images acquired inthe study area before and after the fire. The analysis of the effect of the fire on channeled phenomena included the estimation of (i) the overland flow on the basin, (ii) the location of the gully head, (iii) the channel eroded volume, and (iii) the change of the connectivity inside the basin. The analysis of the effect of the fire on rock fall phenomena included the estimation of (i) the increase of rock fall source areas, (ii) the increase of distances travelled by rock masses along the slopes, and (iii) the spatial distribution of the fallen rock blocks. In all models and scenarios we considered the effect of roads. Results showed a significant increase of the susceptibility to slope instability processes after the fire, mainly due to (i) the formation of hydro repellent soil horizons, (ii) the removal of the litter, (iii) the burning of vegetation.
Ferman, Mutaz; Lim, Amanda H; Hossain, Monowar; Siow, Glenn W; Andrews, Jane M
2018-05-14
Multidisciplinary team meetings (MDTMs) have proven efficacy in cancer management. Whilst widely implemented in inflammatory bowel disease (IBD) care, their value is yet to be investigated. We reviewed the performance of MDTMs for IBD patients. Retrospective review of MDTMs from March 2013 to July 2016. Each patient's first MDTM was considered. Data collected included: report production and location, disease factors, recommendation(s), implementation and barriers to implementation. The MDTM process was considered successful when at least top-level recommendations were implemented within 6 months. MDTM attendance included IBD gastroenterologist, surgeons, radiologist, nurses, dieticians, psychologists and clinical trial staff. Initial MDTM encounters for 166 patients were reviewed: 86 females; mean age 40 years; 140 (84.3%) with Crohn's disease; mean disease duration 10.8 years (interquartile range 15 years). Electronic reports were filed for all patients; hard copies in 84%. In 151/166 episodes, all (n=127) or top-line (n=24) recommendations were implemented, although there was a delay beyond 6 months in 5. Of 146 patients with a successful MDTM, 85 (58.2%) were in clinical remission at last review (median follow-up 27 months). Amongst patients with unsuccessful MDTMs (n=13), only 2 (15.4%) were in clinical remission at follow-up. Barriers to implementation included patients declining recommendations and loss to follow-up. The majority of MDTM encounters were successful from both a process and clinical outcome perspective. System opportunities to improve the process include ensuring 100% reports are available and addressing implementation delays. Patient factors to address include improved engagement and understanding reasons for declining recommendations. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.
NASA Astrophysics Data System (ADS)
Ohkubo, Tomomasa; Sato, Yuji; Matsunaga, Ei-ichi; Tsukamoto, Masahiro
2018-02-01
Although laser processing is widely used for many applications, the cutting quality of carbon fiber reinforced plastic (CFRP) decreases around the heat-affected zone (HAZ) during laser processing. Carbon fibers are exposed around the HAZ, and tensile strength decreases with increasing length of the HAZ. Some theoretical studies of thermal conductions that do not consider fluid dynamics have been performed; however, theoretical considerations that include the dynamics of laser ablation are scarce. Using removed mass and depth observed from experiments, the dynamics of laser ablation of CFRP with high-temperature and high-pressure of compressive gas is simulated herein. In this calculation, the mushroom-like shape of laser ablation is qualitatively simulated compared with experiments using a high-speed camera. Considering the removal temperature of the resin and the temperature distribution at each point on the surface, the simulation results suggest that a wide area of the resin is removed when the processing depth is shallow, and a rounded kerf is generated as the processing depth increases.
Green chemistry: development trajectory
NASA Astrophysics Data System (ADS)
Moiseev, I. I.
2013-07-01
Examples of applications of green chemistry methods in heavy organic synthesis are analyzed. Compounds, which can be produced by the processing of the biomass, and the criteria for the selection of the most promising products are summarized. The current status of the ethanol production and processing is considered. The possibilities of the use of high fatty acid triglycerides, glycerol, succinic acid, and isoprene are briefly discussed. The bibliography includes 67 references.
The need for spatially explicit quantification of benefits in invasive-species management.
Januchowski-Hartley, Stephanie R; Adams, Vanessa M; Hermoso, Virgilio
2018-04-01
Worldwide, invasive species are a leading driver of environmental change across terrestrial, marine, and freshwater environments and cost billions of dollars annually in ecological damages and economic losses. Resources limit invasive-species control, and planning processes are needed to identify cost-effective solutions. Thus, studies are increasingly considering spatially variable natural and socioeconomic assets (e.g., species persistence, recreational fishing) when planning the allocation of actions for invasive-species management. There is a need to improve understanding of how such assets are considered in invasive-species management. We reviewed over 1600 studies focused on management of invasive species, including flora and fauna. Eighty-four of these studies were included in our final analysis because they focused on the prioritization of actions for invasive species management. Forty-five percent (n = 38) of these studies were based on spatial optimization methods, and 35% (n = 13) accounted for spatially variable assets. Across all 84 optimization studies considered, 27% (n = 23) explicitly accounted for spatially variable assets. Based on our findings, we further explored the potential costs and benefits to invasive species management when spatially variable assets are explicitly considered or not. To include spatially variable assets in decision-making processes that guide invasive-species management there is a need to quantify environmental responses to invasive species and to enhance understanding of potential impacts of invasive species on different natural or socioeconomic assets. We suggest these gaps could be filled by systematic reviews, quantifying invasive species impacts on native species at different periods, and broadening sources and enhancing sharing of knowledge. © 2017 Society for Conservation Biology.
Due-Window Assignment Scheduling with Variable Job Processing Times
Wu, Yu-Bin
2015-01-01
We consider a common due-window assignment scheduling problem jobs with variable job processing times on a single machine, where the processing time of a job is a function of its position in a sequence (i.e., learning effect) or its starting time (i.e., deteriorating effect). The problem is to determine the optimal due-windows, and the processing sequence simultaneously to minimize a cost function includes earliness, tardiness, the window location, window size, and weighted number of tardy jobs. We prove that the problem can be solved in polynomial time. PMID:25918745
ERIC Educational Resources Information Center
Conklin, Aaron R.
1999-01-01
Discusses the selection process for weight-training machines that are user-friendly and provide the best fit for the training facility. Machine factors to consider include ease of maintenance, adjustability, ease of use, its biomechanics, structural strength, the upholstery and finish used, and its safety. (GR)
ERIC Educational Resources Information Center
Nelson, Donald J.
1985-01-01
Presents a variety of outdoor and classroom activities in which soil is used to teach environmental concepts and to provide students with science process skills practice. Areas considered include: site selection and description; compaction; infiltration rate; temperature; components; water content; and microorganisms. (DH)
Chemical Mixtures and Epidemiologic Fundamentals for Risk Assessment Applications
Risk management options are increasingly being considered early in the risk assessment process to help scope the considerations and bound the inherent complexities related to potential exposures, risk and future clean-up decisions (including acceptable pollutant levels) related t...
ERIC Educational Resources Information Center
McGrath, Joseph E.
1978-01-01
Summarizes research on small group processes by giving a comprehensive account of the types of variables primarily studied in the laboratory. These include group structure, group composition, group size, and group relations. Considers effects of power, leadership, conformity to social norms, and role relationships. (Author/AV)
EPA's Policy on Evaluating Risk to Children
It is the policy of EPA to consider the risks to infants and children consistently and explicitly as a part of risk assessments generated during its decision making process, including the setting of standards to protect public health and the environment.
45 CFR 800.301 - Application process.
Code of Federal Regulations, 2014 CFR
2014-10-01
... Public Welfare Regulations Relating to Public Welfare (Continued) OFFICE OF PERSONNEL MANAGEMENT MULTI... statute requiring competitive bidding, OPM may consider annually applications from health insurance issuers, including groups of health insurance issuers as defined in § 800.20, to participate in the MSPP...
Paz, Concepción; Suárez, Eduardo; Parga, Oscar; Vence, Jesús
2017-09-01
In this study, we have reproduced the cough clearance process with an Eulerian wall film model. The simulated domain is based on realistic geometry from the literature, which has been improved by adding the glottis and epiglottis. The vocal fold movement has been included due to the dynamic mesh method, considering different abduction and adduction angles and velocities. The proposed methodology captures the deformation of the flexible tissue, considers non-Newtonian properties for the mucus, and enables us to reproduce a single cough or a cough epoch. The cough efficiency (CE) has been used to quantify the overall performance of the cough, considering many different boundary conditions, for the analysis of the glottis effect. It was observed that a viscous shear force is the main mechanism in the cough clearance process, while the glottis closure time and the epiglottis position do not have a significant effect on the CE. The cough assistance devices improve the CE, and the enhancement rate grows logarithmically with the operating pressure. The cough can achieve an effective mucus clearance process, even with a fixed glottis. Nevertheless, the glottis closure substantially improves the CE results.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Manteufel, R.D.; Ahola, M.P.; Turner, D.R.
A literature review has been conducted to determine the state of knowledge available in the modeling of coupled thermal (T), hydrologic (H), mechanical (M), and chemical (C) processes relevant to the design and/or performance of the proposed high-level waste (HLW) repository at Yucca Mountain, Nevada. The review focuses on identifying coupling mechanisms between individual processes and assessing their importance (i.e., if the coupling is either important, potentially important, or negligible). The significance of considering THMC-coupled processes lies in whether or not the processes impact the design and/or performance objectives of the repository. A review, such as reported here, is usefulmore » in identifying which coupled effects will be important, hence which coupled effects will need to be investigated by the US Nuclear Regulatory Commission in order to assess the assumptions, data, analyses, and conclusions in the design and performance assessment of a geologic reposit``. Although this work stems from regulatory interest in the design of the geologic repository, it should be emphasized that the repository design implicitly considers all of the repository performance objectives, including those associated with the time after permanent closure. The scope of this review is considered beyond previous assessments in that it attempts with the current state-of-knowledge) to determine which couplings are important, and identify which computer codes are currently available to model coupled processes.« less
NASA Technical Reports Server (NTRS)
Lunn, Griffin M.
2011-01-01
Water recycling and eventual nutrient recovery is crucial for surviving in or past low earth orbit. New approaches and syste.m architecture considerations need to be addressed to meet current and future system requirements. This paper proposes a flexible system architecture that breaks down pretreatment , steps into discrete areas where multiple unit operations can be considered. An overview focusing on the urea and ammonia conversion steps allows an analysis on each process's strengths and weaknesses and synergy with upstream and downstream processing. Process technologies to be covered include chemical pretreatment, biological urea hydrolysis, chemical urea hydrolysis, combined nitrification-denitrification, nitrate nitrification, anammox denitrification, and regenerative ammonia absorption through struvite formation. Biological processes are considered mainly for their ability to both maximize water recovery and to produce nutrients for future plant systems. Unit operations can be considered for traditional equivalent system mass requirements in the near term or what they can provide downstream in the form of usable chemicals or nutrients for the long term closed-loop ecological control and life support system. Optimally this would allow a system to meet the former but to support the latter without major modification.
IDC Re-Engineering Phase 2 System Specification Document Version 1.5
DOE Office of Scientific and Technical Information (OSTI.GOV)
Satpathi, Meara Allena; Burns, John F.; Harris, James M.
This document contains the system specifications derived to satisfy the system requirements found in the IDC System Requirements Document for the IDC Re-Engineering Phase 2 project. This System Specification Document (SSD) defines waveform data processing requirements for the International Data Centre (IDC) of the Comprehensive Nuclear Test Ban Treaty Organization (CTBTO). The routine processing includes characterization of events with the objective of screening out events considered to be consistent with natural phenomena or non-nuclear, man-made phenomena. This document does not address requirements concerning acquisition, processing and analysis of radionuclide data but does include requirements for the dissemination of radionuclide datamore » and products.« less
Turbulent solutions of the equations of fluid motion
NASA Technical Reports Server (NTRS)
Deissler, R. G.
1984-01-01
Some turbulent solutions of the unaveraged Navier-Stokes equations (equations of fluid motion) are reviewed. Those equations are solved numerically in order to study the nonlinear physics of incompressible turbulent flow. Initial three-dimensional cosine velocity fluctuations and periodic boundary conditions are used in most of the work considered. The three components of the mean-square velocity fluctuations are initially equal for the conditions chosen. The resulting solutions show characteristics of turbulence such as the linear and nonlinear excitation of small-scale fluctuations. For the stronger fluctuations, the initially nonrandom flow develops into an apparently random turbulence. Thus randomness or turbulence can arise as a consequence of the structure of the Navier-Stokes equations. The cases considered include turbulence which is statistically homogeneous or inhomogeneous and isotropic or anisotropic. A mean shear is present in some cases. A statistically steady-state turbulence is obtained by using a spatially periodic body force. Various turbulence processes, including the transfer of energy between eddy sizes and between directional components, and the production, dissipation, and spatial diffusion of turbulence, are considered. It is concluded that the physical processes occurring in turbulence can be profitably studied numerically.
Mesoscopic Modeling of Blood Clotting: Coagulation Cascade and Platelets Adhesion
NASA Astrophysics Data System (ADS)
Yazdani, Alireza; Li, Zhen; Karniadakis, George
2015-11-01
The process of clot formation and growth at a site on a blood vessel wall involve a number of multi-scale simultaneous processes including: multiple chemical reactions in the coagulation cascade, species transport and flow. To model these processes we have incorporated advection-diffusion-reaction (ADR) of multiple species into an extended version of Dissipative Particle Dynamics (DPD) method which is considered as a coarse-grained Molecular Dynamics method. At the continuum level this is equivalent to the Navier-Stokes equation plus one advection-diffusion equation for each specie. The chemistry of clot formation is now understood to be determined by mechanisms involving reactions among many species in dilute solution, where reaction rate constants and species diffusion coefficients in plasma are known. The role of blood particulates, i.e. red cells and platelets, in the clotting process is studied by including them separately and together in the simulations. An agonist-induced platelet activation mechanism is presented, while platelets adhesive dynamics based on a stochastic bond formation/dissociation process is included in the model.
Local sensitivity analysis for inverse problems solved by singular value decomposition
Hill, M.C.; Nolan, B.T.
2010-01-01
Local sensitivity analysis provides computationally frugal ways to evaluate models commonly used for resource management, risk assessment, and so on. This includes diagnosing inverse model convergence problems caused by parameter insensitivity and(or) parameter interdependence (correlation), understanding what aspects of the model and data contribute to measures of uncertainty, and identifying new data likely to reduce model uncertainty. Here, we consider sensitivity statistics relevant to models in which the process model parameters are transformed using singular value decomposition (SVD) to create SVD parameters for model calibration. The statistics considered include the PEST identifiability statistic, and combined use of the process-model parameter statistics composite scaled sensitivities and parameter correlation coefficients (CSS and PCC). The statistics are complimentary in that the identifiability statistic integrates the effects of parameter sensitivity and interdependence, while CSS and PCC provide individual measures of sensitivity and interdependence. PCC quantifies correlations between pairs or larger sets of parameters; when a set of parameters is intercorrelated, the absolute value of PCC is close to 1.00 for all pairs in the set. The number of singular vectors to include in the calculation of the identifiability statistic is somewhat subjective and influences the statistic. To demonstrate the statistics, we use the USDA’s Root Zone Water Quality Model to simulate nitrogen fate and transport in the unsaturated zone of the Merced River Basin, CA. There are 16 log-transformed process-model parameters, including water content at field capacity (WFC) and bulk density (BD) for each of five soil layers. Calibration data consisted of 1,670 observations comprising soil moisture, soil water tension, aqueous nitrate and bromide concentrations, soil nitrate concentration, and organic matter content. All 16 of the SVD parameters could be estimated by regression based on the range of singular values. Identifiability statistic results varied based on the number of SVD parameters included. Identifiability statistics calculated for four SVD parameters indicate the same three most important process-model parameters as CSS/PCC (WFC1, WFC2, and BD2), but the order differed. Additionally, the identifiability statistic showed that BD1 was almost as dominant as WFC1. The CSS/PCC analysis showed that this results from its high correlation with WCF1 (-0.94), and not its individual sensitivity. Such distinctions, combined with analysis of how high correlations and(or) sensitivities result from the constructed model, can produce important insights into, for example, the use of sensitivity analysis to design monitoring networks. In conclusion, the statistics considered identified similar important parameters. They differ because (1) with CSS/PCC can be more awkward because sensitivity and interdependence are considered separately and (2) identifiability requires consideration of how many SVD parameters to include. A continuing challenge is to understand how these computationally efficient methods compare with computationally demanding global methods like Markov-Chain Monte Carlo given common nonlinear processes and the often even more nonlinear models.
Space and Industrial Brine Drying Technologies
NASA Technical Reports Server (NTRS)
Jones, Harry W.; Wisniewski, Richard S.; Flynn, Michael; Shaw, Hali
2014-01-01
This survey describes brine drying technologies that have been developed for use in space and industry. NASA has long considered developing a brine drying system for the International Space Station (ISS). Possible processes include conduction drying in many forms, spray drying, distillation, freezing and freeze drying, membrane filtration, and electrical processes. Commercial processes use similar technologies. Some proposed space systems combine several approaches. The current most promising candidates for use on the ISS use either conduction drying with membrane filtration or spray drying.
Electron Driven Processes in Atmospheric Behaviour
NASA Astrophysics Data System (ADS)
Campbell, L.; Brunger, M. J.; Teubner, P. J. O.
2006-11-01
Electron impact plays an important role in many atmospheric processes. Calculation of these is important for basic understanding, atmospheric modeling and remote sensing. Accurate atomic and molecular data, including electron impact cross sections, are required for such calculations. Five electron-driven processes are considered: auroral and dayglow emissions, the reduction of atmospheric electron density by vibrationally excited N2, NO production and infrared emission from NO. In most cases the predictions are compared with measurements. The dependence on experimental atomic and molecular data is also investigated.
Molina, Manuel; Mota, Manuel; Ramos, Alfonso
2015-01-01
This work deals with mathematical modeling through branching processes. We consider sexually reproducing animal populations where, in each generation, the number of progenitor couples is determined in a non-predictable environment. By using a class of two-sex branching processes, we describe their demographic dynamics and provide several probabilistic and inferential contributions. They include results about the extinction of the population and the estimation of the offspring distribution and its main moments. We also present an application to salmonid populations.
Ruocco, Nadia; Costantini, Susan; Palumbo, Flora; Costantini, Maria
2017-01-01
Enzymes play key roles in different cellular processes, for example, in signal transduction, cell differentiation and proliferation, metabolic processes, DNA damage repair, apoptosis, and response to stress. A deregulation of enzymes has been considered one of the first causes of several diseases, including cancers. In the last several years, enzyme inhibitors, being good candidates as drugs in the pathogenic processes, have received an increasing amount of attention for their potential application in pharmacology. The marine environment is considered a challenging source of enzyme inhibitors for pharmacological applications. In this review, we report on secondary metabolites with enzyme inhibitory activity, focusing our attention on marine sponges and bacteria as promising sources. In the case of sponges, we only reported the kinase inhibitors, because this class was the most representative isolated so far from these marine organisms. PMID:28604647
Rose, Amanda J.; Rudolph, Karen D.
2011-01-01
Theory and research on sex differences in adjustment focus largely on parental, societal, and biological influences. However, it also is important to consider how peers contribute to girls’ and boys’ development. This paper provides a critical review of sex differences in: several peer-relationship processes, including behavioral and social-cognitive styles, stress and coping, and relationship provisions. Based on this review, a speculative peer-socialization model is presented that considers the implications of these sex differences for girls’ and boys’ emotional and behavioral development. Central to this model is the idea that sex-linked relationship processes have costs and benefits for girls’ and boys’ adjustment. Finally, we present recent research testing certain model components and propose approaches for testing understudied aspects of the model. PMID:16435959
Rivela, B; Moreira, M T; Bornhardt, C; Méndez, R; Feijoo, G
2004-03-15
A representative leather tannery industry in a Latin American developing country has been studied from an environmental point of view, including both technical and economic analysis. Life Cycle Analysis (LCA) methodology has been used for the quantification and evaluation of the impacts of the chromium tanning process as a basis to propose further improvement actions. Four main subsystems were considered: beamhouse, tanyard, retanning, and wood furnace. Damages to human health, ecosystem quality, and resources are mainly produced by the tanyard subsystem. The control and reduction of chromium and ammonia emissions are the critical points to be considered to improve the environmental performance of the process. Technologies available for improved management of chromium tanning were profoundly studied, and improvement actions related to optimized operational conditions and a high exhaustion chrome-tanning process were selected. These actions related to the implementation of internal procedures affected the economy of the process with savings ranging from US dollars 8.63 to US dollars 22.5 for the processing of 1 ton of wet salt hides, meanwhile the global environmental impact was reduced to 44-50%. Moreover, the treatment of wastewaters was considered in two scenarios. Primary treatment presented the largest reduction of the environmental impact of the tanning process, while no significant improvement for the evaluated impact categories was achieved when combining primary and secondary treatments.
NASA Technical Reports Server (NTRS)
Casasent, D.
1978-01-01
The article discusses several optical configurations used for signal processing. Electronic-to-optical transducers are outlined, noting fixed window transducers and moving window acousto-optic transducers. Folded spectrum techniques are considered, with reference to wideband RF signal analysis, fetal electroencephalogram analysis, engine vibration analysis, signal buried in noise, and spatial filtering. Various methods for radar signal processing are described, such as phased-array antennas, the optical processing of phased-array data, pulsed Doppler and FM radar systems, a multichannel one-dimensional optical correlator, correlations with long coded waveforms, and Doppler signal processing. Means for noncoherent optical signal processing are noted, including an optical correlator for speech recognition and a noncoherent optical correlator.
NASA Astrophysics Data System (ADS)
Chang, S. S. L.
State of the art technology in circuits, fields, and electronics is discussed. The principles and applications of these technologies to industry, digital processing, microwave semiconductors, and computer-aided design are explained. Important concepts and methodologies in mathematics and physics are reviewed, and basic engineering sciences and associated design methods are dealt with, including: circuit theory and the design of magnetic circuits and active filter synthesis; digital signal processing, including FIR and IIR digital filter design; transmission lines, electromagnetic wave propagation and surface acoustic wave devices. Also considered are: electronics technologies, including power electronics, microwave semiconductors, GaAs devices, and magnetic bubble memories; digital circuits and logic design.
Counseling the Gifted and Talented.
ERIC Educational Resources Information Center
Silverman, Linda Kreger, Ed.
This graduate-level textbook provides a framework for understanding giftedness, and considers the counseling process and strategies for counseling in the schools. Chapters include: "The Gifted Individual" (Linda Kreger Silverman); "The Quest for Meaning: Counseling Issues with Gifted Children and Adolescents" (Deirdre V. Lovecky); "A Developmental…
Fuzzy-Trace Theory and False Memory: New Frontiers.
ERIC Educational Resources Information Center
Reyna, Valerie F.; Brainerd, C. J.
1998-01-01
Describes the origins of fuzzy-trace theory, including Piagetian, interference, information-processing, and judgment and decision-making influences. Discusses similarities and differences between fuzzy-trace theory and other approaches to memory falsification. Considers the theory's predictions regarding age differences in memory falsification and…
Perceptual-Motor Behavior and Educational Processes.
ERIC Educational Resources Information Center
Cratty, Bryant J.
Addressed to elementary school and special class teachers, the text presents research-based information on perceptual-motor behavior and education, including movement and the human personality, research guidelines, and movement activities in general education. Special education is considered and perceptual motor abilities are discussed with…
Nonverbal Behavior in Speech Acts.
ERIC Educational Resources Information Center
Key, Mary Ritchie
In forming a theory of communicative interaction between human beings it is necessary to consider some general features implicit in the communicative process. These include the context of situation, philosophical categories, psycholinguistic categories, grammatical categories, and nonverbal categories. Most of these are extra-linguistic and have…
ERIC Educational Resources Information Center
Crowley, Sharon, Ed.
1976-01-01
This issue of the "Arizona English Bulletin" includes articles concerned with philosophy, psychology, and procedure in the composition classroom at all levels of instruction. Among the topics considered are contending with critics of composition, the back-to-basics movement, the writing process, writing modules, remedial writing, personalized…
Individualized Education Programs for Students with Autism: Including Parents in the Process.
ERIC Educational Resources Information Center
Simpson, Richard L.
1995-01-01
The involvement of parents in developing individualized education programs (IEPs) for their children with autism is discussed. Essential components of IEP documents are outlined, and strategies that professionals can use to promote significant family involvement are considered. (Author/SW)
NASA Technical Reports Server (NTRS)
Proctor, B. W.; Reysa, R. P.; Russell, D. J.
1975-01-01
Housekeeping, off-duty, and medical data concerning the appliances considered for the space station are presented. Appliance functions analyzed include: cleanup, collection, processing and storage of refuse; crew entertainment and physical exercise, and the autoclaves and ergometers.
Computing and Office Automation: Changing Variables.
ERIC Educational Resources Information Center
Staman, E. Michael
1981-01-01
Trends in computing and office automation and their applications, including planning, institutional research, and general administrative support in higher education, are discussed. Changing aspects of information processing and an increasingly larger user community are considered. The computing literacy cycle may involve programming, analysis, use…
ERIC Educational Resources Information Center
Update on the Courts, 1996
1996-01-01
This serial issue concerns itself with several conflicts between individual rights and allegedly wrongful acts that the Supreme Court has not considered previously. The articles on these topics illuminate the constitutional issues of equal protection, due process, and freedom of expression. Specific issues addressed include: (1) equal educational…
Manufacturing and quality control of interconnecting wire harnesses, Volume 2
NASA Technical Reports Server (NTRS)
1972-01-01
Interconnecting wire harnesses defined in the design standard are considered, including type 4, open bundle (not enclosed). Knowledge gained through experience on the Saturn 5 program coupled with recent advances in techniques, materials, and processes was incorporated into the document.
49 CFR 229.211 - Processing of petitions.
Code of Federal Regulations, 2012 CFR
2012-10-01
... to the U.S. Department of Transportation Docket Operations (M-30), West Building Ground Floor, Room... requires additional information to appropriately consider the petition, FRA will conduct a hearing on the..., or both which may include validated computer modeling, structural crush analysis, component testing...
49 CFR 229.211 - Processing of petitions.
Code of Federal Regulations, 2013 CFR
2013-10-01
... to the U.S. Department of Transportation Docket Operations (M-30), West Building Ground Floor, Room... requires additional information to appropriately consider the petition, FRA will conduct a hearing on the..., or both which may include validated computer modeling, structural crush analysis, component testing...
49 CFR 229.211 - Processing of petitions.
Code of Federal Regulations, 2014 CFR
2014-10-01
... to the U.S. Department of Transportation Docket Operations (M-30), West Building Ground Floor, Room... requires additional information to appropriately consider the petition, FRA will conduct a hearing on the..., or both which may include validated computer modeling, structural crush analysis, component testing...
Colebatch-Bourn, A N; Edwards, C J; Collado, P; D'Agostino, M-A; Hemke, R; Jousse-Joulin, S; Maas, M; Martini, A; Naredo, E; Østergaard, M; Rooney, M; Tzaribachev, N; van Rossum, M A; Vojinovic, J; Conaghan, P G; Malattia, C
2015-11-01
To develop evidence based points to consider the use of imaging in the diagnosis and management of juvenile idiopathic arthritis (JIA) in clinical practice. The task force comprised a group of paediatric rheumatologists, rheumatologists experienced in imaging, radiologists, methodologists and patients from nine countries. Eleven questions on imaging in JIA were generated using a process of discussion and consensus. Research evidence was searched systematically for each question using MEDLINE, EMBASE and Cochrane CENTRAL. Imaging modalities included were conventional radiography, ultrasound, MRI, CT, scintigraphy and positron emission tomography. The experts used the evidence obtained from the relevant studies to develop a set of points to consider. The level of agreement with each point to consider was assessed using a numerical rating scale. A total of 13 277 references were identified from the search process, from which 204 studies were included in the systematic review. Nine points to consider were produced, taking into account the heterogeneity of JIA, the lack of normative data and consequent difficulty identifying pathology. These encompassed the role of imaging in making a diagnosis of JIA, detecting and monitoring inflammation and damage, predicting outcome and response to treatment, use of guided therapies, progression and remission. Level of agreement for each proposition varied according to the research evidence and expert opinion. Nine points to consider and a related research agenda for the role of imaging in the management of JIA were developed using published evidence and expert opinion. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.
NASA Astrophysics Data System (ADS)
Wrożyna, Andrzej; Pernach, Monika; Kuziak, Roman; Pietrzyk, Maciej
2016-04-01
Due to their exceptional strength properties combined with good workability the Advanced High-Strength Steels (AHSS) are commonly used in automotive industry. Manufacturing of these steels is a complex process which requires precise control of technological parameters during thermo-mechanical treatment. Design of these processes can be significantly improved by the numerical models of phase transformations. Evaluation of predictive capabilities of models, as far as their applicability in simulation of thermal cycles thermal cycles for AHSS is considered, was the objective of the paper. Two models were considered. The former was upgrade of the JMAK equation while the latter was an upgrade of the Leblond model. The models can be applied to any AHSS though the examples quoted in the paper refer to the Dual Phase (DP) steel. Three series of experimental simulations were performed. The first included various thermal cycles going beyond limitations of the continuous annealing lines. The objective was to validate models behavior in more complex cooling conditions. The second set of tests included experimental simulations of the thermal cycle characteristic for the continuous annealing lines. Capability of the models to describe properly phase transformations in this process was evaluated. The third set included data from the industrial continuous annealing line. Validation and verification of models confirmed their good predictive capabilities. Since it does not require application of the additivity rule, the upgrade of the Leblond model was selected as the better one for simulation of industrial processes in AHSS production.
Including Emotional Intelligence in Pharmacy Curricula to Help Achieve CAPE Outcomes
Fierke, Kerry K.; Sucher, Brandon J.; Janke, Kristin K.
2015-01-01
The importance of emotional intelligence (EI) for effective teamwork and leadership within the workplace is increasingly apparent. As suggested by the 2013 CAPE Outcomes, we recommend that colleges and schools of pharmacy consider EI-related competencies to build self-awareness and professionalism among students. In this Statement, we provide two examples of the introduction of EI into pharmacy curricula. In addition, we provide a 4-phase process based on recommendations developed by EI experts for structuring and planning EI development. Finally, we make 9 recommendations’ to inform the process of including EI in pharmacy curricula. PMID:26089557
Neyman, Markov processes and survival analysis.
Yang, Grace
2013-07-01
J. Neyman used stochastic processes extensively in his applied work. One example is the Fix and Neyman (F-N) competing risks model (1951) that uses finite homogeneous Markov processes to analyse clinical trials with breast cancer patients. We revisit the F-N model, and compare it with the Kaplan-Meier (K-M) formulation for right censored data. The comparison offers a way to generalize the K-M formulation to include risks of recovery and relapses in the calculation of a patient's survival probability. The generalization is to extend the F-N model to a nonhomogeneous Markov process. Closed-form solutions of the survival probability are available in special cases of the nonhomogeneous processes, like the popular multiple decrement model (including the K-M model) and Chiang's staging model, but these models do not consider recovery and relapses while the F-N model does. An analysis of sero-epidemiology current status data with recurrent events is illustrated. Fix and Neyman used Neyman's RBAN (regular best asymptotic normal) estimates for the risks, and provided a numerical example showing the importance of considering both the survival probability and the length of time of a patient living a normal life in the evaluation of clinical trials. The said extension would result in a complicated model and it is unlikely to find analytical closed-form solutions for survival analysis. With ever increasing computing power, numerical methods offer a viable way of investigating the problem.
Basso, Lorenzo; Dittmaier, Stefan; Huss, Alexander; Oggero, Luisa
We present the extension of two general algorithms for the treatment of infrared singularities arising in electroweak corrections to decay processes at next-to-leading order: the dipole subtraction formalism and the one-cutoff slicing method. The former is extended to the case of decay kinematics which has not been considered in the literature so far. The latter is generalised to production and decay processes with more than two charged particles, where new "surface" terms arise. Arbitrary patterns of massive and massless external particles are considered, including the treatment of infrared singularities in dimensional or mass regularisation. As an application of the two techniques we present the calculation of the next-to-leading order QCD and electroweak corrections to the top-quark decay width including all off-shell and decay effects of intermediate [Formula: see text] bosons. The result, e.g., represents a building block of a future calculation of NLO electroweak effects to off-shell top-quark pair ([Formula: see text]) production. Moreover, this calculation can serve as the first step towards an event generator for top-quark decays at next-to-leading order accuracy, which can be used to attach top-quark decays to complicated many-particle top-quark processes, such as for [Formula: see text] or [Formula: see text].
Evaluation of an urban canopy model in a tropical city: the role of tree evapotranspiration
NASA Astrophysics Data System (ADS)
Liu, Xuan; Li, Xian-Xiang; Harshan, Suraj; Roth, Matthias; Velasco, Erik
2017-09-01
A single layer urban canopy model (SLUCM) with enhanced hydrologic processes, is evaluated in a tropical city, Singapore. The evaluation was performed using an 11 month offline simulation with the coupled Noah land surface model/SLUCM over a compact low-rise residential area. Various hydrological processes are considered, including anthropogenic latent heat release, and evaporation from impervious urban facets. Results show that the prediction of energy fluxes, in particular latent heat flux, is improved when these processes were included. However, the simulated latent heat flux is still underestimated by ∼40%. Considering Singapore’s high green cover ratio, the tree evapotranspiration process is introduced into the model, which significantly improves the simulated latent heat flux. In particular, the systematic error of the model is greatly reduced, and becomes lower than the unsystematic error in some seasons. The effect of tree evapotranspiration on the urban surface energy balance is further demonstrated during an unusual dry spell. The present study demonstrates that even at sites with relatively low (11%) tree coverage, ignoring evapotranspiration from trees may cause serious underestimation of the latent heat flux and atmospheric humidity. The improved model is also transferable to other tropical or temperate regions to study the impact of tree evapotranspiration on urban climate.
Multi-criteria analysis for municipal solid waste management in a Brazilian metropolitan area.
Santos, Simone Machado; Silva, Maisa Mendonça; Melo, Renata Maciel; Gavazza, Savia; Florencio, Lourdinha; Kato, Mario T
2017-10-15
The decision-making process involved in municipal solid waste management (MSWM) must consider more than just financial aspects, which makes it a difficult task in developing countries. The Recife Metropolitan Region (RMR) in the Northeast of Brazil faces a MSWM problem that has been ongoing since the 1970s, with no common solution. In order to direct short-term solutions, three MSWM alternatives were outlined for the RMR, considering the current and future situations, the time and cost involved and social/environmental criteria. A multi-criteria approach, based on the Preference Ranking Organization Method for Enrichment Evaluations (PROMETHEE), was proposed to rank these alternatives. The alternative that included two private landfill sites and seven transfer, sorting and composting stations was confirmed as the most suitable and stable option for short-term MSWM, considering the two scenarios for the criteria weights. Sensitivity analysis was also performed to support the robustness of the results. The implementation of separate collections would minimize the amount of waste buried, while maximizing the useful life of landfill sites and increasing the timeframe of the alternative. Overall, the multi-criteria analysis was helpful and accurate during the alternative selection process, considering the similarities and restrictions of each option, which can lead to difficulties during the decision-making process.
Instantaneous Wavenumber Estimation for Damage Quantification in Layered Plate Structures
NASA Technical Reports Server (NTRS)
Mesnil, Olivier; Leckey, Cara A. C.; Ruzzene, Massimo
2014-01-01
This paper illustrates the application of instantaneous and local wavenumber damage quantification techniques for high frequency guided wave interrogation. The proposed methodologies can be considered as first steps towards a hybrid structural health monitoring/ nondestructive evaluation (SHM/NDE) approach for damage assessment in composites. The challenges and opportunities related to the considered type of interrogation and signal processing are explored through the analysis of numerical data obtained via EFIT simulations of damage in CRFP plates. Realistic damage configurations are modeled from x-ray CT scan data of plates subjected to actual impacts, in order to accurately predict wave-damage interactions in terms of scattering and mode conversions. Simulation data is utilized to enhance the information provided by instantaneous and local wavenumbers and mitigate the complexity related to the multi-modal content of the plate response. Signal processing strategies considered for this purpose include modal decoupling through filtering in the frequency/wavenumber domain, the combination of displacement components, and the exploitation of polarization information for the various modes as evaluated through the dispersion analysis of the considered laminate lay-up sequence. The results presented assess the effectiveness of the proposed wavefield processing techniques as a hybrid SHM/NDE technique for damage detection and quantification in composite, plate-like structures.
The response of an airplane to random atmospheric disturbances
NASA Technical Reports Server (NTRS)
Diederich, Franklin W
1957-01-01
The statistical approach to the gust-load problem which consists in considering flight through turbulent air to be a stationary random process is extended by including the effect of lateral variation of the instantaneous gust intensity on the aerodynamic forces. The forces obtained in this manner are used in dynamic analyses of rigid and flexible airplanes free to move vertically, in pitch, and in roll. The effect of the interaction of longitudinal, vertical, and lateral gusts on the wing stresses is also considered.
NASP guidance design for vehicle autonomy
NASA Astrophysics Data System (ADS)
Wagner, E. A.; Li, I.; Nguyen, D. D.; Nguyen, P. L.
1990-10-01
Vehicle guidance for General Dynamics' NASP vehicle is planned to be self-contained onboard the vehicle, and independent of any ground support during the mission. It will include real-time onboard abort and ascent trajectory optimization capability. Although these features should be considered a natural outgrowth of research in guidance and trajectory optimization and advances in computation, facilitating full vehicle autonomy for NASP represents a significant advance relative to any flight-demonstrated guidance. Algorithms and processing requirements for autonomous NASP vehicle guidance are considered.
Properties of Nonlinear Dynamo Waves
NASA Technical Reports Server (NTRS)
Tobias, S. M.
1997-01-01
Dynamo theory offers the most promising explanation of the generation of the sun's magnetic cycle. Mean field electrodynamics has provided the platform for linear and nonlinear models of solar dynamos. However, the nonlinearities included are (necessarily) arbitrarily imposed in these models. This paper conducts a systematic survey of the role of nonlinearities in the dynamo process, by considering the behaviour of dynamo waves in the nonlinear regime. It is demonstrated that only by considering realistic nonlinearities that are non-local in space and time can modulation of the basic dynamo wave he achieved. Moreover, this modulation is greatest when there is a large separation of timescales provided by including a low magnetic Prandtl number in the equation for the velocity perturbations.
Technology assessment and citizen action
NASA Technical Reports Server (NTRS)
Mottur, E. R.
1975-01-01
Citizen participation in the nation's total social, political, economic decisionmaking processes was studied. Impediments are discussed which prevent citizens from taking effective assessment action; these include finance, organization and motivation, and information. The proposal for establishing citizens assessment associations is considered along with implications of citizen assessment action.
Code of Federal Regulations, 2010 CFR
2010-07-01
... hydrogen ratio. It is essentially non-volatile at ambient temperatures with closed cup flash point of 445... recordkeeping and reporting only, compressors are considered equipment. In hydrogen service means that a... sufficient storage facilities for the product. For the purpose of this subpart, process unit includes any...
The Public Library Trustee and Changing Community Needs.
ERIC Educational Resources Information Center
The Bookmark, 1987
1987-01-01
This issue of "The Bookmark" contains 23 essays examining the challenges facing public library trustees and changing community needs. Topics considered include: the role of the trustee, fund raising, lobbying and the legislative process, library building programs, library automation, literacy, intellectual freedom, information access, preschool…
IMPLEMENTING NONPROFESSIONAL PROGRAMS IN HUMAN SERVICES. MANPOWER TRAINING SERIES.
ERIC Educational Resources Information Center
SCHMAIS, AARON
SPECIFIC PROCESSES FOR UTILIZING NONPROFESSIONAL EMPLOYEES IN HUMAN SERVICES ARE PRESENTED. THE BACKGROUND, CURRENT STATUS, AND PROBLEMS ARE DISCUSSED. THE ELEMENTS CONSIDERED ARE RECRUITMENT, SCREENING AND SELECTION, TRAINING, PLACEMENT, SUPERVISION, UPGRADING, AND EVALUATION. EXAMPLES OF NONPROFESSIONAL POSITIONS INCLUDE THE CASE AIDE IN SOCIAL…
Families and Professionals as Collaborators in Assessment.
ERIC Educational Resources Information Center
Crais, Elizabeth R.
1993-01-01
This paper considers issues affecting collaboration of professionals and family members in assessing children with special needs. Issues include process versus outcome, the balance of power between families and professionals, choices available to families, sequencing of services, formal versus informal assessment, family concerns and priorities,…
Microcomputers and Workstations in Libraries: Trends and Opportunities.
ERIC Educational Resources Information Center
Welsch, Erwin K.
1990-01-01
Summarizes opinions of scholars in various disciplines on workstation history, definition, and functions. Networks and configurations for library workstations, including hardware and software recommendations, are described. The impact of workstations on the workplace resulting in task, process, and institutional transformation, is also considered.…
A COMPARATIVE ANALYSIS OF THE RESEARCH UTILIZATION PROCESS.
ERIC Educational Resources Information Center
LIPPITT, RONALD; AND OTHERS
A SUGGESTED MODEL FOR ADEQUATE DISSEMINATION OF RESEARCH FINDINGS CONSIDERS FOUR PRIMARY BARRIERS TO EFFECTIVE COMMUNICATION--(1) DIVISION OF PERSONNEL LABOR INTO TASK ROLES, (2) INSTITUTIONAL DISTINCTIONS, (3) DEVELOPMENT OF PROFESSIONAL REFERENCE GROUPS, AND (4) GEOGRAPHICAL DIVISIONS. SUGGESTED SOLUTIONS INCLUDE LINKING SYSTEMS AND ROLES,…
HOMEOTHERMY: DOES IT IMPEDE THE RESPONSE TO CELLULAR INJURY
Homeostasis of core temperature is considered to be one of the most precise regulatory processes. n this paper it is postulated that homeothermy is so effective, especially in species of-relatively large mass (including humans), that it limits the ability to survive ischemia, tox...
Virtual Libraries: Service Realities.
ERIC Educational Resources Information Center
Novak, Jan
This paper discusses client service issues to be considered when transitioning to a virtual library situation. Themes related to the transitional nature of society in the knowledge era are presented, including: paradox and a contradictory nature; blurring of boundaries; networks, systems, and holistic thinking; process/not product, becoming/not…
NASA Technical Reports Server (NTRS)
Phen, R. L.; Luckow, W. K.; Mattson, L.; Otth, D.; Tsou, P.
1977-01-01
Development criteria and recommendations for coal feed system selections that include supporting data are presented. Considered are the areas of coal feed coasts, coal feed system reliability, and the interaction of the feed system with the conversion process.
ERIC Educational Resources Information Center
Johnson, Robert L.
2005-01-01
High-performance schools are facilities that improve the learning environment while saving energy, resources and money. Creating a high-performance school requires an integrated design approach. Key systems--including lighting, HVAC, electrical and plumbing--must be considered from the beginning of the design process. According to William H.…
Incorporating the patient experience into regulatory decision making in the USA, Europe, and Canada.
Kluetz, Paul G; O'Connor, Daniel J; Soltys, Katherine
2018-05-01
The clinical development of cancer therapeutics is a global undertaking, and incorporation of the patient experience into the clinical decision-making process is of increasing interest to the international regulatory and health policy community. Disease and treatment-related symptoms and their effect on patient function and health-related quality of life are important outcomes to consider. The identification of methods to scientifically assess, analyse, interpret, and present these clinical outcomes requires sustained international collaboration by multiple stakeholders including patients, clinicians, scientists, and policy makers. Several data sources can be considered to capture the patient experience, including patient-reported outcome (PRO) measures, performance measures, wearable devices, and biosensors, as well as the careful collection and analysis of clinical events and supportive care medications. In this Policy Review, we focus on PRO measures and present the perspectives of three international regulatory scientists to identify areas of common ground regarding opportunities to incorporate rigorous PRO data into the regulatory decision-making process. Copyright © 2018 Elsevier Ltd. All rights reserved.
Curbing Inflammation in the Ischemic Heart Disease
Evora, Paulo Roberto B.; Nather, Julio; Tubino, Paulo Victor; Albuquerque, Agnes Afrodite S.; Celotto, Andrea Carla; Rodrigues, Alfredo J.
2013-01-01
A modern concept considers acute coronary syndrome as an autoinflammatory disorder. From the onset to the healing stage, an endless inflammation has been presented with complex, multiple cross-talk mechanisms at the molecular, cellular, and organ levels. Inflammatory response following acute myocardial infarction has been well documented since the 1940s and 1950s, including increased erythrocyte sedimentation rate, the C-reactive protein analysis, and the determination of serum complement. It is surprising to note, based on a wide literature overview including the following 30 years (decades of 1960, 1970, and 1980), that the inflammatory acute myocardium infarction lost its focus, virtually disappearing from the literature reports. The reversal of this historical process occurs in the 1990s with the explosion of studies involving cytokines. Considering the importance of inflammation in the pathophysiology of ischemic heart disease, the aim of this paper is to present a conceptual overview in order to explore the possibility of curbing this inflammatory process. PMID:23819098
Integrality in Brazil and Venezuela: similarities and complementarities.
Santos, Carla Targino Bruno Dos; Barros, Ione Silva; Amorim, Anne Caroline Coelho Leal Árias; Rocha, Dais Gonçalves; Mendonça, Ana Valéria Machado; Sousa, Maria Fátima de
2018-04-01
This study aims to compare Primary Health Care (PHC) in Brazil and Venezuela, considering its characteristics as to integrality. It has a qualitative approach, using documental analysis, semi-structured interviews with key informants and field diary notes. We observed the three realms of integrality inherent to the health work process: comprehensive and holistic care, the individual viewed as a complex being with multiple needs, requiring the connection of various health knowledge; continuity of care in institutional micro-policy with interprofessional articulation, in order to consider individual care; continuity of care in macro-policy, when a shift to other levels of care is needed; intersectoriality was also included, when the needs of an individual and community require a cross-sectoral coordination, with action on determinants and conditionants of the health-disease process. It is worth highlighting the natural tendency to include a comprehensive community medical training. We conclude that those countries strengthened by democracy draw their integrality practices closer, as well as the construction of social and health policies for underprivileged populations to achieve equity.
Dynamic Reciprocity in the Wound Microenvironment
Schultz, Gregory S.; Davidson, Jeffrey M.; Kirsner, Robert S.; Bornstein, Paul; Herman, Ira M.
2011-01-01
Here, we define dynamic reciprocity (DR) as an ongoing, bidirectional interaction amongst cells and their surrounding microenvironment. In the review, we posit that DR is especially meaningful during wound healing as the DR-driven biochemical, biophysical and cellular responses to injury play pivotal roles in regulating tissue regenerative responses. Such cell-extracellular matrix interactions not only guide and regulate cellular morphology, but cellular differentiation, migration, proliferation, and survival during tissue development, including e.g. embryogenesis, angiogenesis, as well as during pathologic processes including cancer diabetes, hypertension and chronic wound healing. Herein, we examine DR within the wound microenvironment while considering specific examples across acute and chronic wound healing. This review also considers how a number of hypotheses that attempt to explain chronic wound pathophysiology, which may be understood within the DR framework. The implications of applying the principles of dynamic reciprocity to optimize wound care practice and future development of innovative wound healing therapeutics are also briefly considered. PMID:21362080
Energy transfer processes between Tm(3+) and Ho(3+) in LiYF4. Ph.D. Thesis Final Report
NASA Technical Reports Server (NTRS)
Oezen, Goenuel
1991-01-01
The spectroscopic properties of the crystal LiYF4 doped with Thulium (Tm) and Holmium (Ho) ions are studied. The basic processes are discussed that regulate the transfer of energy between these two ions in this crystal. In this system Tm is considered the donor ion and the Ho the acceptor ion. Spectral data were obtained on three samples available: LiYF4:Tm(3+) (0.5 percent), LiYF4:Ho(3+) (1 percent), and LiYF4:Tm(3+) (5 percent), Ho(3+) (0.2 percent). Spectral data, which include absorption, luminescence, excitation, and the response to pulsed excitation in a wide range of temperatures, allowed to look at the energy transfer processes by considering the kinetic evolution of the emission of the two ions (donor and acceptor) involved in the process and the basic spectroscopic properties related to them. This inclusive approach has led to the validation of the physical model.
NASA Astrophysics Data System (ADS)
Kuz`michev, V. S.; Filinov, E. P.; Ostapyuk, Ya A.
2018-01-01
This article describes how the thrust level influences the turbojet architecture (types of turbomachines that provide the maximum efficiency) and its working process parameters (turbine inlet temperature (TIT) and overall pressure ratio (OPR)). Functional gasdynamic and strength constraints were included, total mass of fuel and the engine required for mission and the specific fuel consumption (SFC) were considered optimization criteria. Radial and axial turbines and compressors were considered. The results show that as the engine thrust decreases, optimal values of working process parameters decrease too, and the regions of compromise shrink. Optimal engine architecture and values of working process parameters are suggested for turbojets with thrust varying from 100N to 100kN. The results show that for the thrust below 25kN the engine scale factor should be taken into the account, as the low flow rates begin to influence the efficiency of engine elements substantially.
Zamora, Gerardo; Meneses, Daniela; De-Regil, Luz Maria; Neufeld, Lynnette; Peña-Rosas, Juan Pablo; Sinisterra, Odalis Teresa
2015-03-01
The World Health Organization (WHO) follows a complex and rigorous process to develop global guidelines. With regard to nutrition-related guidelines, the joint participation of national authorities from Member States and their partners, including those of the social economy, is key to strengthening the process of evidence-informed guideline development and the subsequent implementation as part of national public health strategies. WHO puts forward a series of tools that can assist national authorities on health and social development in the elaboration of evidence-informed policies, considering their pertinence, relevance and implementability. This adoption and adaptation process must consider equity in order to avoid widening existing inequities. WHO global nutrition guidelines contribute to the effective implementation of nutrition interventions in Member States. Two experiences of implementation, one in Panama and one in Peru, exemplify this process. The paper ends by suggesting a deeper understanding and utilization of implementation research during programmes to identify what factors ensure effective interventions, appropriate scale up strategies and greater health equity.
Donehew, G R
1979-01-01
Although pharmacists are developing interest in many types of pharmacy practice, they are still spending the bulk of their time in the prescription dispensing process. Any effort to provide motivation must consider the prescription dispensing process. The pharmacy literature includes only a few studies that dealt with pharmacists as people. The studies usually showed that pharmacists basically were unhappy with their jobs. In developing a motivational climate for pharmacists, pharmacy supervisors have several concepts to consider: the hierarchy of needs by Maslow; the expectancy theory by Hampton; the gygiene-motivator theory by Herzberg; and the Theory Y management approach by McGregor. Because pharmacists must be induced to enter and remain in an organization, supervisors should be aware of the need to use any technique available in developing a motivational climate.
Yao, Zhitong; Li, Jinhui; Zhao, Xiangyang
2011-08-01
Molten salt oxidation (MSO), a robust thermal but non-flame process, has the inherent capability of destroying organic constituents in wastes, while retaining inorganic and radioactive materials in situ. It has been considered as an alternative to incineration and may be a solution to many waste disposal problems. The present review first describes the history and development of MSO, as well as design and engineering details, and then focuses on reaction mechanisms and its potential applications in various wastes, including hazardous wastes, medical wastes, mixed wastes, and energetic materials. Finally, the current status of and prospects for the MSO process and directions for future research are considered. Copyright © 2011 Elsevier Ltd. All rights reserved.
Zhao, Chuan-Li; Hsu, Hua-Feng
2014-01-01
This paper considers single machine scheduling and due date assignment with setup time. The setup time is proportional to the length of the already processed jobs; that is, the setup time is past-sequence-dependent (p-s-d). It is assumed that a job's processing time depends on its position in a sequence. The objective functions include total earliness, the weighted number of tardy jobs, and the cost of due date assignment. We analyze these problems with two different due date assignment methods. We first consider the model with job-dependent position effects. For each case, by converting the problem to a series of assignment problems, we proved that the problems can be solved in O(n 4) time. For the model with job-independent position effects, we proved that the problems can be solved in O(n 3) time by providing a dynamic programming algorithm. PMID:25258727
Performance bounds on parallel self-initiating discrete-event
NASA Technical Reports Server (NTRS)
Nicol, David M.
1990-01-01
The use is considered of massively parallel architectures to execute discrete-event simulations of what is termed self-initiating models. A logical process in a self-initiating model schedules its own state re-evaluation times, independently of any other logical process, and sends its new state to other logical processes following the re-evaluation. The interest is in the effects of that communication on synchronization. The performance is considered of various synchronization protocols by deriving upper and lower bounds on optimal performance, upper bounds on Time Warp's performance, and lower bounds on the performance of a new conservative protocol. The analysis of Time Warp includes the overhead costs of state-saving and rollback. The analysis points out sufficient conditions for the conservative protocol to outperform Time Warp. The analysis also quantifies the sensitivity of performance to message fan-out, lookahead ability, and the probability distributions underlying the simulation.
Zhao, Chuan-Li; Hsu, Chou-Jung; Hsu, Hua-Feng
2014-01-01
This paper considers single machine scheduling and due date assignment with setup time. The setup time is proportional to the length of the already processed jobs; that is, the setup time is past-sequence-dependent (p-s-d). It is assumed that a job's processing time depends on its position in a sequence. The objective functions include total earliness, the weighted number of tardy jobs, and the cost of due date assignment. We analyze these problems with two different due date assignment methods. We first consider the model with job-dependent position effects. For each case, by converting the problem to a series of assignment problems, we proved that the problems can be solved in O(n(4)) time. For the model with job-independent position effects, we proved that the problems can be solved in O(n(3)) time by providing a dynamic programming algorithm.
Multiscale Structure of UXO Site Characterization: Spatial Estimation and Uncertainty Quantification
DOE Office of Scientific and Technical Information (OSTI.GOV)
Ostrouchov, George; Doll, William E.; Beard, Les P.
2009-01-01
Unexploded ordnance (UXO) site characterization must consider both how the contamination is generated and how we observe that contamination. Within the generation and observation processes, dependence structures can be exploited at multiple scales. We describe a conceptual site characterization process, the dependence structures available at several scales, and consider their statistical estimation aspects. It is evident that most of the statistical methods that are needed to address the estimation problems are known but their application-specific implementation may not be available. We demonstrate estimation at one scale and propose a representation for site contamination intensity that takes full account of uncertainty,more » is flexible enough to answer regulatory requirements, and is a practical tool for managing detailed spatial site characterization and remediation. The representation is based on point process spatial estimation methods that require modern computational resources for practical application. These methods have provisions for including prior and covariate information.« less
Attitude change: persuasion and social influence.
Wood, W
2000-01-01
This chapter reviews empirical and theoretical developments in research on social influence and message-based persuasion. The review emphasizes research published during the period from 1996-1998. Across these literatures, three central motives have been identified that generate attitude change and resistance. These involve concerns with the self, with others and the rewards/punishments they can provide, and with a valid understanding of reality. The motives have implications for information processing and for attitude change in public and private contexts. Motives in persuasion also have been investigated in research on attitude functions and cognitive dissonance theory. In addition, the chapter reviews the relatively unique aspects of each literature: In persuasion, it considers the cognitive and affective mechanisms underlying attitude change, especially dual-mode processing models, recipients' affective reactions, and biased processing. In social influence, the chapter considers how attitudes are embedded in social relations, including social identity theory and majority/minority group influence.
Zaĭtseva, N V; Trusov, P V; Kir'ianov, D A
2012-01-01
The mathematic concept model presented describes accumulation of functional disorders associated with environmental factors, plays predictive role and is designed for assessments of possible effects caused by heterogenous factors with variable exposures. Considering exposure changes with self-restoration process opens prospects of using the model to evaluate, analyse and manage occupational risks. To develop current theoretic approaches, the authors suggested a model considering age-related body peculiarities, systemic interactions of organs, including neuro-humoral regulation, accumulation of functional disorders due to external factors, rehabilitation of functions during treatment. General objective setting covers defining over a hundred unknow coefficients that characterize speed of various processes within the body. To solve this problem, the authors used iteration approach, successive identification, that starts from the certain primary approximation of the model parameters and processes subsequent updating on the basis of new theoretic and empirical knowledge.
Pulsed excimer laser processing for cost-effective solar cells
NASA Technical Reports Server (NTRS)
Wong, David C.
1985-01-01
The application of excimer laser in the fabrication of photovoltaic devices was investigated extensively. Processes included junction formation, laser assisted chemical vapor deposition metallization, and laser assisted chemical vapor deposition surface passivation. Results demonstrated that implementation of junction formation by laser annealing in production is feasible because of excellent control in junction depth and quality. Both metallization and surface passivation, however, were found impractical to be considered for manufacturing at this stage.
Code of Federal Regulations, 2011 CFR
2011-01-01
... the natural environment of a site but does not include changes desirable for the temporary use of the... Radiation Control Act of 1978 (92 Stat. 3021), any State or any political subdivision of, or any political... by the Nuclear Materials Management and Safeguards System. This process is considered complete when...
No Effect of Writing Advice on Reading Comprehension
ERIC Educational Resources Information Center
Balling, Laura Winther
2018-01-01
This article considers text comprehension through the integrated perspectives of language processing research and practical writing advice as expressed in writing guides and language policies. Such guides for instance include advice to use active constructions instead of passives and sentences instead of nominalizations. These recommended and…
Disorders of Articulation. Prentice-Hall Foundations of Speech Pathology Series.
ERIC Educational Resources Information Center
Carrell, James A.
Designed for students of speech pathology and audiology and for practicing clinicians, the text considers the nature of the articulation process, criteria for diagnosis, and classification and etiology of disorders. Also discussed are phonetic characteristics, including phonemic errors and configurational and contextual defects; and functional…
Molecules in Living Systems: A Biochemistry Module. Teacher's Guide.
ERIC Educational Resources Information Center
Martin, David; Sampugna, Joseph; Sandoval, Amado
This teacher's guide provides information and resources for helping to familiarize students with chemistry and its everyday applications around the world using inquiry and investigations. Contents include: (1) "Introducing Molecules in Living Systems"; (2) "Considering Life Processes"; (3) "Understanding the Structure of Biomolecules"; (4)…
Cognitive Factors in Academic Achievement.
ERIC Educational Resources Information Center
Cuasay, Peter
1992-01-01
This review explores the factors of cognitive processing, style, and metacognitive organization as they contribute to academic success. Specific discussions consider aspects of short- and long-term memory, including how these affect learning and academic performance, and the keys to attaining long-term memory capability by involving redundancy,…
ERIC Educational Resources Information Center
Hickey, Raymond, Ed.
This collection of papers considers processes involved in language change and issues of how they can be modeled and studied. After "Introduction" (Raymond Hickey), there are 15 papers in 6 parts. Part 1, "The Phenomenon of Language Change," includes: (1) "On Change in 'E-language'" (Peter Matthews); and (2)…
Sustaining biodiversity in Midwestern woodlands
Douglas Ladd
1997-01-01
Woodland ecosystems in the Midwestern United States provide habitat for an impressive array of biodiversity, including endemic organisms. Sustainable conservation of high quality woodland landscapes must consider the genesis, process regimes, and ecological dynamics of these systems, both in contemporary and presettlement tine frames. An essential goal of conservation...
Space Station Planetology Experiments (SSPEX)
NASA Technical Reports Server (NTRS)
Greeley, R. (Editor); Williams, R. J. (Editor)
1986-01-01
A meeting of 50 planetary scientists considered the uses of the Space Station to support experiments in their various disciplines. Abstracts (28) present concepts for impact and aeolian processes, particle formation and interaction, and other planetary science experiments. Summaries of the rationale, hardware concepts, accomodations, and recommendations are included.
The Charge of the Byte Brigade: Educators Lead the Fourth Revolution.
ERIC Educational Resources Information Center
Gardner, David Pierpont
1986-01-01
Opportunities provided by computer technologies are considered from two perspectives: what they are enabling teachers and researchers to do and implications for the future. Processing information, opening access to the library, and coordinating telecommunications are discussed, including the University of California MELVYL system. (MLW)
Preparing for the Integration of Emerging Technologies.
ERIC Educational Resources Information Center
Dyrli, Odvard Egil; Kinnaman, Daniel E.
1994-01-01
Discussion of the process of integrating new technologies into schools considers the evolution of technology, including personal computers, CD-ROMs, hypermedia, and networking/communications; the transition from Industrial-Age to Information-Age schools; and the logical steps of transition. Sidebars discuss a networked multimedia pilot project and…
Image Tracing: An Analysis of Its Effectiveness in Children's Pictorial Discrimination Learning
ERIC Educational Resources Information Center
Levin, Joel R.; And Others
1977-01-01
A total of 45 fifth grade students were the subjects of an experiment offering support for a component of learning strategy (memory imagery). Various theoretical explanations of the image-tracing phenomenon are considered, including depth of processing, dual coding and frequency. (MS)
Code of Federal Regulations, 2010 CFR
2010-01-01
... the natural environment of a site but does not include changes desirable for the temporary use of the... Radiation Control Act of 1978 (92 Stat. 3021), any State or any political subdivision of, or any political... by the Nuclear Materials Management and Safeguards System. This process is considered complete when...
Solar Thermal | Climate Neutral Research Campuses | NREL
for research campuses. The following links go to sections that describe when and where solar thermal water consumption, or process heat for research. On-campus applications include concentrating solar incentives and rebates available? Is financing available? Research campuses should consider the following
48 CFR 50.103-5 - Processing cases.
Code of Federal Regulations, 2011 CFR
2011-10-01
... before receiving advice that the funds will be available. The request for this advice shall give the... to decide a given case. Facts and evidence, including signed statements of material facts within the... considering requests for amendment without consideration involving another agency shall obtain advice on the...
Emotional Intelligence Tests: Potential Impacts on the Hiring Process for Accounting Students
ERIC Educational Resources Information Center
Nicholls, Shane; Wegener, Matt; Bay, Darlene; Cook, Gail Lynn
2012-01-01
Emotional intelligence is increasingly recognized as being important for professional career success. Skills related to emotional intelligence (e.g. organizational commitment, public speaking, teamwork, and leadership) are considered essential. Human resource professionals have begun including tests of emotional intelligence (EI) in job applicant…
ERIC Educational Resources Information Center
Costin, Frank
Challenges to the psychology teacher are considered, including engaging students in the learning process, helping students develop a historical perspective in their study of psychology, and dealing with controversial topics. Resistance to answering questions is likely to be greatest when the lecturer asks for highly specific facts. Students may be…
Numerical Differentiation of Noisy, Nonsmooth Data
Chartrand, Rick
2011-01-01
We consider the problem of differentiating a function specified by noisy data. Regularizing the differentiation process avoids the noise amplification of finite-difference methods. We use total-variation regularization, which allows for discontinuous solutions. The resulting simple algorithm accurately differentiates noisy functions, including those which have a discontinuous derivative.
Evaluate Yourself. Evaluation: Research-Based Decision Making Series, Number 9304.
ERIC Educational Resources Information Center
Fetterman, David M.
This document considers both self-examination and external evaluation of gifted and talented education programs. Principles of the self-examination process are offered, noting similarities to external evaluation models. Principles of self-evaluation efforts include the importance of maintaining a nonjudgmental orientation, soliciting views from…
Electron molecular ion recombination: product excitation and fragmentation.
Adams, Nigel G; Poterya, Viktoriya; Babcock, Lucia M
2006-01-01
Electron-ion dissociative recombination is an important ionization loss process in any ionized gas containing molecular ions. This includes the interstellar medium, circumstellar shells, cometary comae, planetary ionospheres, fusion plasma boundaries, combustion flames, laser plasmas and chemical deposition and etching plasmas. In addition to controlling the ionization density, the process generates many radical species, which can contribute to a parallel neutral chemistry. Techniques used to obtain rate data and product information (flowing afterglows and storage rings) are discussed and recent data are reviewed including diatomic to polyatomic ions and cluster ions. The data are divided into rate coefficients and cross sections, including their temperature/energy dependencies, and quantitative identification of neutral reaction products. The latter involve both ground and electronically excited states and including vibrational excitation. The data from the different techniques are compared and trends in the data are examined. The reactions are considered in terms of the basic mechanisms (direct and indirect processes including tunneling) and recent theoretical developments are discussed. Finally, new techniques are mentioned (for product identification; electrostatic storage rings, including single and double rings; Coulomb explosion) and new ways forward are suggested.
[Some new phenomena of culturally legitimate examples of family formation].
Mozny, I
1987-01-01
Recent changes in the process of family formation in Czechoslovakia are described. These include a reversal of the trends toward lower rates of illegitimacy and lower ages at marriage and increases in the number of divorces, the popularity of consensual unions, and the percent of marriages following pregnancy. Factors affecting consensual union are considered, including educational status, birth order, and marital status. (SUMMARY IN ENG AND RUS)
Critical Protection Item classification for a waste processing facility at Savannah River Site
DOE Office of Scientific and Technical Information (OSTI.GOV)
Ades, M.J.; Garrett, R.J.
1993-10-01
This paper describes the methodology for Critical Protection Item (CPI) classification and its application to the Structures, Systems and Components (SSC) of a waste processing facility at the Savannah River Site (SRS). The WSRC methodology for CPI classification includes the evaluation of the radiological and non-radiological consequences resulting from postulated accidents at the waste processing facility and comparison of these consequences with allowable limits. The types of accidents considered include explosions and fire in the facility and postulated accidents due to natural phenomena, including earthquakes, tornadoes, and high velocity straight winds. The radiological analysis results indicate that CPIs are notmore » required at the waste processing facility to mitigate the consequences of radiological release. The non-radiological analysis, however, shows that the Waste Storage Tank (WST) and the dike spill containment structures around the formic acid tanks in the cold chemical feed area and waste treatment area of the facility should be identified as CPIs. Accident mitigation options are provided and discussed.« less
Minois, Nathan; Savy, Stéphanie; Lauwers-Cances, Valérie; Andrieu, Sandrine; Savy, Nicolas
2017-03-01
Recruiting patients is a crucial step of a clinical trial. Estimation of the trial duration is a question of paramount interest. Most techniques are based on deterministic models and various ad hoc methods neglecting the variability in the recruitment process. To overpass this difficulty the so-called Poisson-gamma model has been introduced involving, for each centre, a recruitment process modelled by a Poisson process whose rate is assumed constant in time and gamma-distributed. The relevancy of this model has been widely investigated. In practice, rates are rarely constant in time, there are breaks in recruitment (for instance week-ends or holidays). Such information can be collected and included in a model considering piecewise constant rate functions yielding to an inhomogeneous Cox model. The estimation of the trial duration is much more difficult. Three strategies of computation of the expected trial duration are proposed considering all the breaks, considering only large breaks and without considering breaks. The bias of these estimations procedure are assessed by means of simulation studies considering three scenarios of breaks simulation. These strategies yield to estimations with a very small bias. Moreover, the strategy with the best performances in terms of prediction and with the smallest bias is the one which does not take into account of breaks. This result is important as, in practice, collecting breaks data is pretty hard to manage.
System design from mission definition to flight validation
NASA Technical Reports Server (NTRS)
Batill, S. M.
1992-01-01
Considerations related to the engineering systems design process and an approach taken to introduce undergraduate students to that process are presented. The paper includes details on a particular capstone design course. This course is a team oriented aircraft design project which requires the students to participate in many phases of the system design process, from mission definition to validation of their design through flight testing. To accomplish this in a single course requires special types of flight vehicles. Relatively small-scale, remotely piloted vehicles have provided the class of aircraft considered in this course.
Tug fleet and ground operations schedules and controls. Volume 3: Program cost estimates
NASA Technical Reports Server (NTRS)
1975-01-01
Cost data for the tug DDT&E and operations phases are presented. Option 6 is the recommended option selected from seven options considered and was used as the basis for ground processing estimates. Option 6 provides for processing the tug in a factory clean environment in the low bay area of VAB with subsequent cleaning to visibly clean. The basis and results of the trade study to select Option 6 processing plan is included. Cost estimating methodology, a work breakdown structure, and a dictionary of WBS definitions is also provided.
Aircraft gas turbine materials and processes.
Kear, B H; Thompson, E R
1980-05-23
Materials and processing innovations that have been incorporated into the manufacture of critical components for high-performance aircraft gas turbine engines are described. The materials of interest are the nickel- and cobalt-base superalloys for turbine and burner sections of the engine, and titanium alloys and composites for compressor and fan sections of the engine. Advanced processing methods considered include directional solidification, hot isostatic pressing, superplastic foring, directional recrystallization, and diffusion brazing. Future trends in gas turbine technology are discussed in terms of materials availability, substitution, and further advances in air-cooled hardware.
Simons, Pascale A M; Ramaekers, Bram; Hoebers, Frank; Kross, Kenneth W; Marneffe, Wim; Pijls-Johannesma, Madelon; Vandijck, Dominique
2015-07-01
Compared with new technologies, the redesign of care processes is generally considered less attractive to improve patient outcomes. Nevertheless, it might result in better patient outcomes, without further increasing costs. Because early initiation of treatment is of vital importance for patients with head and neck cancer (HNC), these care processes were redesigned. This study aimed to assess patient outcomes and cost-effectiveness of this redesign. An economic (Markov) model was constructed to evaluate the biopsy process of suspicious lesion under local instead of general anesthesia, and combining computed tomography and positron emission tomography for diagnostics and radiotherapy planning. Patients treated for HNC were included in the model stratified by disease location (larynx, oropharynx, hypopharynx, and oral cavity) and stage (I-II and III-IV). Probabilistic sensitivity analyses were performed. Waiting time before treatment start reduced from 5 to 22 days for the included patient groups, resulting in 0.13 to 0.66 additional quality-adjusted life-years. The new workflow was cost-effective for all the included patient groups, using a ceiling ratio of €80,000 or €20,000. For patients treated for tumors located at the larynx and oral cavity, the new workflow resulted in additional quality-adjusted life-years, and costs decreased compared with the regular workflow. The health care payer benefited €14.1 million and €91.5 million, respectively, when individual net monetary benefits were extrapolated to an organizational level and a national level. The redesigned care process reduced the waiting time for the treatment of patients with HNC and proved cost-effective. Because care improved, implementation on a wider scale should be considered. Copyright © 2015 International Society for Pharmacoeconomics and Outcomes Research (ISPOR). Published by Elsevier Inc. All rights reserved.
Exergie /4th revised and enlarged edition/
NASA Astrophysics Data System (ADS)
Baloh, T.; Wittwer, E.
The theoretical concept of exergy is explained and its practical applications are discussed. Equilibrium and thermal equilibrium are reviewed as background, and exergy is considered as a reference point for solid-liquid, liquid-liquid, and liquid-gas systems. Exergetic calculations and their graphic depictions are covered. The concepts of enthalpy and entropy are reviewed in detail, including their applications to gas mixtures, solutions, and isolated substances. The exergy of gas mixtures, solutions, and isolated substances is discussed, including moist air, liquid water in water vapor, dry air, and saturation-limited solutions. Mollier exergy-enthalpy-entropy diagrams are presented for two-component systems, and exergy losses for throttling, isobaric mixing, and heat transfer are addressed. The relationship of exergy to various processes is covered, including chemical processes, combustion, and nuclear reactions. The optimization of evaporation plants through exergy is discussed. Calculative examples are presented for energy production and heating, industrial chemical processes, separation of liquid air, nuclear reactors, and others.
Curtis, Gary P.; Kohler, Matthias; Kannappan, Ramakrishnan; Briggs, Martin A.; Day-Lewis, Frederick D.
2015-01-01
Scientifically defensible predictions of field scale U(VI) transport in groundwater requires an understanding of key processes at multiple scales. These scales range from smaller than the sediment grain scale (less than 10 μm) to as large as the field scale which can extend over several kilometers. The key processes that need to be considered include both geochemical reactions in solution and at sediment surfaces as well as physical transport processes including advection, dispersion, and pore-scale diffusion. The research summarized in this report includes both experimental and modeling results in batch, column and tracer tests. The objectives of this research were to: (1) quantify the rates of U(VI) desorption from sediments acquired from a uranium contaminated aquifer in batch experiments;(2) quantify rates of U(VI) desorption in column experiments with variable chemical conditions, and(3) quantify nonreactive tracer and U(VI) transport in field tests.
Patients' involvement in improvement initiatives: a qualitative systematic review.
van, Claire; McInerney, Patricia; Cooke, Richard
2015-10-01
Over the last 20 years, quality improvement in health has become an important strategy in health services in many countries. With the emphasis on quality health care, there has been a shift in social paradigms towards including service users in their own health on different levels. There is growing evidence in literature on the positive impact on health outcomes where patients are active participants in their personal care. There is however less information available on the broader influence of users on improvement in systems. The objective of this review was to identify the barriers and enablers to patients being involved in quality improvement efforts directed towards their own health care. This review considered studies that included adults and children of any age experiencing any health problem.The review considered studies that explored patient or user participation in quality improvement and the factors enabling and hindering this processThe qualitative component of this review considered studies that focused on qualitative data, including, but not limited to, designs such as phenomenology, grounded theory, ethnography, action research and feminist research. Other texts such as opinion papers and reports were also considered. The search strategy aimed to find both published and unpublished studies. A three-step search strategy was utilized in this review. The searches using all identified keywords and index terms included the databases PubMed, PsycINFO, Medline, Scopus, EBSCOhost and CINAHL.Qualitative, text and opinion papers were considered for inclusion in this review.Closely related concepts like community involvement, family involvement, patients' involvement in their own care (for example, in the case of shared decision making), and patient centeredness in the context of a consultation were excluded. Qualitative and textual papers selected for retrieval were assessed by two independent reviewers for authenticity prior to inclusion in the review using the standardized critical appraisal instruments from the Joanna Briggs Institute. Qualitative and textual data were extracted from papers included in the review using the standardized data extraction tool from the Joanna Briggs Institute. The above findings were pooled and through the identification of categories, a final meta-synthesis was formulated. Two synthesized findings were created from the included papers. Firstly, there are barriers to patients' participation in quality improvement in health and in spite of policy support for user involvement in quality improvement, it is a difficult strategy to implement. The second synthesized finding was that there are enablers to patients' involvement in quality improvement: when patients are involved in quality improvement efforts in health care, there are innovative, often unexpected, outcomes at different levels of the process, and sustaining these efforts is possible with ongoing individual or group support.Five categories which supported the synthesized findings were created through the meta-aggregative process. There are enablers and barriers to involving patients in quality improvement in health care that need to be considered when planning such interventions.Relationships and roles will need to be very clear from the outset. A developmental approach needs to be considered where support and training is part of the project. Where patients are truly engaged in service improvement, unexpected innovation occurs.There are many more reports and opinion papers published regarding this topic than there are rigorous research studies. This leaves the field open to the development of good methodological studies related to quality improvement and in particular to the participation of patients.
Information extraction from Italian medical reports: An ontology-driven approach.
Viani, Natalia; Larizza, Cristiana; Tibollo, Valentina; Napolitano, Carlo; Priori, Silvia G; Bellazzi, Riccardo; Sacchi, Lucia
2018-03-01
In this work, we propose an ontology-driven approach to identify events and their attributes from episodes of care included in medical reports written in Italian. For this language, shared resources for clinical information extraction are not easily accessible. The corpus considered in this work includes 5432 non-annotated medical reports belonging to patients with rare arrhythmias. To guide the information extraction process, we built a domain-specific ontology that includes the events and the attributes to be extracted, with related regular expressions. The ontology and the annotation system were constructed on a development set, while the performance was evaluated on an independent test set. As a gold standard, we considered a manually curated hospital database named TRIAD, which stores most of the information written in reports. The proposed approach performs well on the considered Italian medical corpus, with a percentage of correct annotations above 90% for most considered clinical events. We also assessed the possibility to adapt the system to the analysis of another language (i.e., English), with promising results. Our annotation system relies on a domain ontology to extract and link information in clinical text. We developed an ontology that can be easily enriched and translated, and the system performs well on the considered task. In the future, it could be successfully used to automatically populate the TRIAD database. Copyright © 2017 Elsevier B.V. All rights reserved.
Ground Test of the Urine Processing Assembly for Accelerations and Transfer Functions
NASA Technical Reports Server (NTRS)
Houston, Janice; Almond, Deborah F. (Technical Monitor)
2001-01-01
This viewgraph presentation gives an overview of the ground test of the urine processing assembly for accelerations and transfer functions. Details are given on the test setup, test data, data analysis, analytical results, and microgravity assessment. The conclusions of the tests include the following: (1) the single input/multiple output method is useful if the data is acquired by tri-axial accelerometers and inputs can be considered uncorrelated; (2) tying coherence with the matrix yields higher confidence in results; (3) the WRS#2 rack ORUs need to be isolated; (4) and future work includes a plan for characterizing performance of isolation materials.
What do government agencies consider in the debate over added sugars
USDA-ARS?s Scientific Manuscript database
The place of sugars in the U.S. diet is vigorously debated with much attention on added sugars, those added during processing or preparation of foodstuffs, particularly as they relate to obesity. Federal government agencies have different responsibilities related to the food supply including researc...
Executive Function and Mathematics Achievement: Are Effects Construct- and Time-General or Specific?
ERIC Educational Resources Information Center
Duncan, Robert; Nguyen, Tutrang; Miao, Alicia; McClelland, Megan; Bailey, Drew
2016-01-01
Executive function (EF) is considered a set of interrelated cognitive processes, including inhibitory control, working memory, and attentional shifting, that are connected to the development of the prefrontal cortex and contribute to children's problem solving skills and self regulatory behavior (Best & Miller, 2010; Garon, Bryson, &…
Adolescents' Conscious Processes of Developing Regulation: Learning to Appraise Challenges
ERIC Educational Resources Information Center
Larson, Reed W.
2011-01-01
To understand regulation and agency, it important to consider the nature of the regulatory challenges that adolescents must deal with. These include emotional, motivation, interpersonal, and other obstacles and problems. In this chapter, the author discusses the challenges reported by youth working on arts, technology, and social justice projects…
Roles in Literacy Learning: A New Perspective.
ERIC Educational Resources Information Center
Tovey, Duane R., Ed.; Kerber, James E., Ed.
Refining and better understanding the roles parents, teachers, administrators, and researchers play in helping children learn to process written language is the focus of this book. Part 1 considers the role of the parents and includes the following articles: "Learning to Read: It Starts in the Home" (David B. Doake): "Let's Read…
Code of Federal Regulations, 2011 CFR
2011-04-01
... INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT... through the application process. The Secretary will consider: (a) The specific energy resource development...) The history of the tribe's role in energy resource development, including negotiating and approval or...
This Administrator Assessment Center Aims for Excellence.
ERIC Educational Resources Information Center
Hughes, Larry W.; And Others
1986-01-01
Describes the assessment center of the Leadership Academy in the Houston (Texas) schools system. It is used to evaluate the management capability of current principals and potential administrator candidates. The center uses simulation exercises as part of the evaluation process. Includes outline of areas to be considered when developing a program.…
Molecules in Living Systems: A Biochemistry Module.
ERIC Educational Resources Information Center
Martin, David; Sampugna, Joseph
This book is one in a series of Interdisciplinary Approaches to Chemistry (IAC). The purpose of this guide is to familiarize students with chemistry and its everyday applications around the world using inquiry and investigations. Contents include: (1) "Considering Life Processes"; (2) "Understanding the Structure of Biomolecules"; (3) "Properties…
Optical Signal Processing for ASW
1963-05-01
considered here. In the initial 1. Weissbein, L. , and O’Brien, S. J., "Attenuation of Thermal Radiation with Phototropic Colorants, " Contract DA-129-QM...COORDINATE Fig. A-1 Energy Diagram of Phototropic Mechanisms Included in Category ii can assume that the A--B conversion of a single local system
CD-ROM Integration Peaks Student Interest in Inquiry.
ERIC Educational Resources Information Center
O'Bannon, Blanche
1997-01-01
Discussion of learning processes examines past educational practices and considers how CD-ROM technology can impact teaching and learning. A lesson plan for elementary school science that uses a CD-ROM encyclopedia is presented that includes instructional goals, performance objectives, teaching and learning activities, and assessment methods.…
Federal Register 2010, 2011, 2012, 2013, 2014
2011-07-28
... considered but eliminated from detailed analysis include conventional uranium mining and milling, conventional mining and heap leach processing, alternative site location, alternate lixiviants, and alternate...'s Agencywide Document Access and Management System (ADAMS), which provides text and image files of...
State vs. Local Control: Reality or Myth over Concern for Local Autonomy.
ERIC Educational Resources Information Center
Mundt, John C.
1978-01-01
As examples of the trend towards decision-making processes resting on the interaction of various legitimate public sector interests, the author considers outside forces producing operational strictures within the system, including executive orders, lapsing and allotment procedures, accounting requirements, information demands, legal opinions,…
An Analytical Framework for Evaluating E-Commerce Business Models and Strategies.
ERIC Educational Resources Information Center
Lee, Chung-Shing
2001-01-01
Considers electronic commerce as a paradigm shift, or a disruptive innovation, and presents an analytical framework based on the theories of transaction costs and switching costs. Topics include business transformation process; scale effect; scope effect; new sources of revenue; and e-commerce value creation model and strategy. (LRW)
Parental Depressive Symptoms and Children's Sleep: The Role of Family Conflict
ERIC Educational Resources Information Center
El-Sheikh, Mona; Kelly, Ryan J.; Bagley, Erika J.; Wetter, Emily K.
2012-01-01
Background: We used a multi-method and multi-informant design to identify developmental pathways through which parental depressive symptoms contribute to children's sleep problems. Environmental factors including adult inter-partner conflict and parent-child conflict were considered as process variables of this relation. Methods: An ethnically and…
Issues in the Intellectual Assessment of Hearing Impaired Children
ERIC Educational Resources Information Center
Hughes, Deana; Sapp, Gary L.; Kohler, Maxie P.
2006-01-01
The assessment of hearing impaired children is fraught with a number of problems. These include lack of valid assessment measures, faulty theoretical assumptions, lack of knowledge regarding the functioning of cognitive processes of these children, and biases against these children. This article briefly considers these issues and describes a study…
NASA Technical Reports Server (NTRS)
Aguilera, Frank J.
2015-01-01
A guiding principle for conducting research in technology, science, and engineering, leading to innovation is based on our use of research methodology (both qualitative and qualitative). A brief review of research methodology will be presented with an overview of NASA process in developing aeronautics technologies and other things to consider in research including what is innovation.
Common Sense Planning for a Computer, or, What's It Worth to You?
ERIC Educational Resources Information Center
Crawford, Walt
1984-01-01
Suggests factors to be considered in planning for the purchase of a microcomputer, including budgets, benefits, costs, and decisions. Major uses of a personal computer are described--word processing, financial analysis, file and database management, programming and computer literacy, education, entertainment, and thrill of high technology. (EJS)
Proper Installation Improves Carpet Life.
ERIC Educational Resources Information Center
Grogan, Ralph
1998-01-01
Explains how proper carpet installation can add to carpet life; includes tips to consider before signing a carpet-installation purchasing agreement that can make the new carpet a better investment. Topics cover how color selection lengthens appearance life, the need for moisture testing, the importance of carpet seams in the purchasing process,…
Developmental Planning: An Introduction for Parents
ERIC Educational Resources Information Center
Noland, Jim
2009-01-01
"Developmental Planning" is the thinking process of using developmental milestones as a general basis for planning and predicting needs for the child within the early years. It considers the time frames associated with normal development across all facets of the child's development. The areas include bone and joint development, movement, sensory…
ON THE NATURE OF SPEECH SCIENCE.
ERIC Educational Resources Information Center
PETERSON, GORDON E.
IN THIS ARTICLE THE NATURE OF THE DISCIPLINE OF SPEECH SCIENCE IS CONSIDERED AND THE VARIOUS BASIC AND APPLIED AREAS OF THE DISCIPLINE ARE DISCUSSED. THE BASIC AREAS ENCOMPASS THE VARIOUS PROCESSES OF THE PHYSIOLOGY OF SPEECH PRODUCTION, THE ACOUSTICAL CHARACTERISTICS OF SPEECH, INCLUDING THE SPEECH WAVE TYPES AND THE INFORMATION-BEARING ACOUSTIC…
NASA Technical Reports Server (NTRS)
Aguilera, Frank J.
2015-01-01
A guiding principle for conducting research in technology, science, and engineering, leading to innovation is based on our use of research methodology (both qualitative and quantitative). A brief review of research methodology will be presented with an overview of NASA process in developing aeronautics technologies and other things to consider in research including what is innovation.
USDA-ARS?s Scientific Manuscript database
Several parameters of Microwave-assisted extraction (MAE) including extraction time, extraction temperature, ethanol concentration and solid-liquid ratio were selected to describe the MAE processing. The silybin content, measured by an UV-Vis spectrophotometry, was considered as the silymarin yield....
Development and validation of an educational booklet for healthy eating during pregnancy1
de Oliveira, Sheyla Costa; Lopes, Marcos Venícios de Oliveira; Fernandes, Ana Fátima Carvalho
2014-01-01
OBJECTIVE: to describe the validation process of an educational booklet for healthy eating in pregnancy using local and regional food. METHODS: methodological study, developed in three steps: construction of the educational booklet, validation of the educational material by judges, and by pregnant women. The validation process was conducted by 22 judges and 20 pregnant women, by convenience selection. We considered a p-value<0.85 to validate the booklet compliance and relevance, according to the six items of the instrument. As for content validation, the item-level Content Validity Index (I-CVI) was considered when a minimum score of at least 0.80 was obtained. RESULTS: five items were considered relevant by the judges. The mean I-CVI was 0.91. The pregnant women evaluated positively the booklet. The suggestions were accepted and included in the final version of the material. CONCLUSION: the booklet was validated in terms of content and relevance, and should be used by nurses for advice on healthy eating during pregnancy. PMID:25296145
Process of pulmonary rehabilitation and program organization.
Wouters, E F M; Augustin, I M L
2011-09-01
Pulmonary rehabilitation programs are highly directed to return patients suffering from chronic lung diseases to a state of self-help. These programs are largely organized as temporary interventions in a highly fragmented delivery care system for patients with chronic respiratory conditions. In an optimal health care organizational structure, pulmonary rehabilitation needs to be considered as an essential part of an individualized, integrated care process, organized from the vantage point of the patient and the patients'health continuum. Pulmonary rehabilitation programs need to become organized as patient-centered care, respectful of and responsive to individual patient preferences, needs and values. Partnering and communication skills are considered as drivers for successful rehabilitation. Assessment is considered as the cornerstone to evaluate the individual needs and problems in order to develop an individualized intervention. Pulmonary rehabilitation programs need to move away from a supply-driven functional organizational structure towards integrated structures, including the full range of medical expertise, technical skills and specialized facilities needed to compete on added value in the management of patients with chronic respiratory diseases.
Multiphase porous media modelling: A novel approach to predicting food processing performance.
Khan, Md Imran H; Joardder, M U H; Kumar, Chandan; Karim, M A
2018-03-04
The development of a physics-based model of food processing is essential to improve the quality of processed food and optimize energy consumption. Food materials, particularly plant-based food materials, are complex in nature as they are porous and have hygroscopic properties. A multiphase porous media model for simultaneous heat and mass transfer can provide a realistic understanding of transport processes and thus can help to optimize energy consumption and improve food quality. Although the development of a multiphase porous media model for food processing is a challenging task because of its complexity, many researchers have attempted it. The primary aim of this paper is to present a comprehensive review of the multiphase models available in the literature for different methods of food processing, such as drying, frying, cooking, baking, heating, and roasting. A critical review of the parameters that should be considered for multiphase modelling is presented which includes input parameters, material properties, simulation techniques and the hypotheses. A discussion on the general trends in outcomes, such as moisture saturation, temperature profile, pressure variation, and evaporation patterns, is also presented. The paper concludes by considering key issues in the existing multiphase models and future directions for development of multiphase models.
Audio-visual presentation of information for informed consent for participation in clinical trials.
Synnot, Anneliese; Ryan, Rebecca; Prictor, Megan; Fetherstonhaugh, Deirdre; Parker, Barbara
2014-05-09
Informed consent is a critical component of clinical research. Different methods of presenting information to potential participants of clinical trials may improve the informed consent process. Audio-visual interventions (presented, for example, on the Internet or on DVD) are one such method. We updated a 2008 review of the effects of these interventions for informed consent for trial participation. To assess the effects of audio-visual information interventions regarding informed consent compared with standard information or placebo audio-visual interventions regarding informed consent for potential clinical trial participants, in terms of their understanding, satisfaction, willingness to participate, and anxiety or other psychological distress. We searched: the Cochrane Central Register of Controlled Trials (CENTRAL), The Cochrane Library, issue 6, 2012; MEDLINE (OvidSP) (1946 to 13 June 2012); EMBASE (OvidSP) (1947 to 12 June 2012); PsycINFO (OvidSP) (1806 to June week 1 2012); CINAHL (EbscoHOST) (1981 to 27 June 2012); Current Contents (OvidSP) (1993 Week 27 to 2012 Week 26); and ERIC (Proquest) (searched 27 June 2012). We also searched reference lists of included studies and relevant review articles, and contacted study authors and experts. There were no language restrictions. We included randomised and quasi-randomised controlled trials comparing audio-visual information alone, or in conjunction with standard forms of information provision (such as written or verbal information), with standard forms of information provision or placebo audio-visual information, in the informed consent process for clinical trials. Trials involved individuals or their guardians asked to consider participating in a real or hypothetical clinical study. (In the earlier version of this review we only included studies evaluating informed consent interventions for real studies). Two authors independently assessed studies for inclusion and extracted data. We synthesised the findings using meta-analysis, where possible, and narrative synthesis of results. We assessed the risk of bias of individual studies and considered the impact of the quality of the overall evidence on the strength of the results. We included 16 studies involving data from 1884 participants. Nine studies included participants considering real clinical trials, and eight included participants considering hypothetical clinical trials, with one including both. All studies were conducted in high-income countries.There is still much uncertainty about the effect of audio-visual informed consent interventions on a range of patient outcomes. However, when considered across comparisons, we found low to very low quality evidence that such interventions may slightly improve knowledge or understanding of the parent trial, but may make little or no difference to rate of participation or willingness to participate. Audio-visual presentation of informed consent may improve participant satisfaction with the consent information provided. However its effect on satisfaction with other aspects of the process is not clear. There is insufficient evidence to draw conclusions about anxiety arising from audio-visual informed consent. We found conflicting, very low quality evidence about whether audio-visual interventions took more or less time to administer. No study measured researcher satisfaction with the informed consent process, nor ease of use.The evidence from real clinical trials was rated as low quality for most outcomes, and for hypothetical studies, very low. We note, however, that this was in large part due to poor study reporting, the hypothetical nature of some studies and low participant numbers, rather than inconsistent results between studies or confirmed poor trial quality. We do not believe that any studies were funded by organisations with a vested interest in the results. The value of audio-visual interventions as a tool for helping to enhance the informed consent process for people considering participating in clinical trials remains largely unclear, although trends are emerging with regard to improvements in knowledge and satisfaction. Many relevant outcomes have not been evaluated in randomised trials. Triallists should continue to explore innovative methods of providing information to potential trial participants during the informed consent process, mindful of the range of outcomes that the intervention should be designed to achieve, and balancing the resource implications of intervention development and delivery against the purported benefits of any intervention.More trials, adhering to CONSORT standards, and conducted in settings and populations underserved in this review, i.e. low- and middle-income countries and people with low literacy, would strengthen the results of this review and broaden its applicability. Assessing process measures, such as time taken to administer the intervention and researcher satisfaction, would inform the implementation of audio-visual consent materials.
Results from the VALUE perfect predictor experiment: process-based evaluation
NASA Astrophysics Data System (ADS)
Maraun, Douglas; Soares, Pedro; Hertig, Elke; Brands, Swen; Huth, Radan; Cardoso, Rita; Kotlarski, Sven; Casado, Maria; Pongracz, Rita; Bartholy, Judit
2016-04-01
Until recently, the evaluation of downscaled climate model simulations has typically been limited to surface climatologies, including long term means, spatial variability and extremes. But these aspects are often, at least partly, tuned in regional climate models to match observed climate. The tuning issue is of course particularly relevant for bias corrected regional climate models. In general, a good performance of a model for these aspects in present climate does therefore not imply a good performance in simulating climate change. It is now widely accepted that, to increase our condidence in climate change simulations, it is necessary to evaluate how climate models simulate relevant underlying processes. In other words, it is important to assess whether downscaling does the right for the right reason. Therefore, VALUE has carried out a broad process-based evaluation study based on its perfect predictor experiment simulations: the downscaling methods are driven by ERA-Interim data over the period 1979-2008, reference observations are given by a network of 85 meteorological stations covering all European climates. More than 30 methods participated in the evaluation. In order to compare statistical and dynamical methods, only variables provided by both types of approaches could be considered. This limited the analysis to conditioning local surface variables on variables from driving processes that are simulated by ERA-Interim. We considered the following types of processes: at the continental scale, we evaluated the performance of downscaling methods for positive and negative North Atlantic Oscillation, Atlantic ridge and blocking situations. At synoptic scales, we considered Lamb weather types for selected European regions such as Scandinavia, the United Kingdom, the Iberian Pensinsula or the Alps. At regional scales we considered phenomena such as the Mistral, the Bora or the Iberian coastal jet. Such process-based evaluation helps to attribute biases in surface variables to underlying processes and ultimately to improve climate models.
The violent interstellar medium
NASA Technical Reports Server (NTRS)
Mccray, R.; Snow, T. P., Jr.
1979-01-01
Observational evidence for high-velocity and high-temperature interstellar gas is reviewed. The physical processes that characterize this gas are described, including the ionization and emissivity of coronal gas, the behavior and appearance of high-velocity shocks, and interfaces between coronal gas and cooler interstellar gas. Hydrodynamical models for the action of supernova explosions and stellar winds on the interstellar medium are examined, and recent attempts to synthesize all the processes considered into a global model for the interstellar medium are discussed.
Savannah River Site Spent Nuclear Fuel Management Final Environmental Impact Statement
DOE Office of Scientific and Technical Information (OSTI.GOV)
N /A
The proposed DOE action considered in this environmental impact statement (EIS) is to implement appropriate processes for the safe and efficient management of spent nuclear fuel and targets at the Savannah River Site (SRS) in Aiken County, South Carolina, including placing these materials in forms suitable for ultimate disposition. Options to treat, package, and store this material are discussed. The material included in this EIS consists of approximately 68 metric tons heavy metal (MTHM) of spent nuclear fuel 20 MTHM of aluminum-based spent nuclear fuel at SRS, as much as 28 MTHM of aluminum-clad spent nuclear fuel from foreign andmore » domestic research reactors to be shipped to SRS through 2035, and 20 MTHM of stainless-steel or zirconium-clad spent nuclear fuel and some Americium/Curium Targets stored at SRS. Alternatives considered in this EIS encompass a range of new packaging, new processing, and conventional processing technologies, as well as the No Action Alternative. A preferred alternative is identified in which DOE would prepare about 97% by volume (about 60% by mass) of the aluminum-based fuel for disposition using a melt and dilute treatment process. The remaining 3% by volume (about 40% by mass) would be managed using chemical separation. Impacts are assessed primarily in the areas of water resources, air resources, public and worker health, waste management, socioeconomic, and cumulative impacts.« less
Planning as an Iterative Process
NASA Technical Reports Server (NTRS)
Smith, David E.
2012-01-01
Activity planning for missions such as the Mars Exploration Rover mission presents many technical challenges, including oversubscription, consideration of time, concurrency, resources, preferences, and uncertainty. These challenges have all been addressed by the research community to varying degrees, but significant technical hurdles still remain. In addition, the integration of these capabilities into a single planning engine remains largely unaddressed. However, I argue that there is a deeper set of issues that needs to be considered namely the integration of planning into an iterative process that begins before the goals, objectives, and preferences are fully defined. This introduces a number of technical challenges for planning, including the ability to more naturally specify and utilize constraints on the planning process, the ability to generate multiple qualitatively different plans, and the ability to provide deep explanation of plans.
LSA silicon material task closed-cycle process development
NASA Technical Reports Server (NTRS)
Roques, R. A.; Wakefield, G. F.; Blocher, J. M., Jr.; Browning, M. F.; Wilson, W.
1979-01-01
The initial effort on feasibility of the closed cycle process was begun with the design of the two major items of untested equipment, the silicon tetrachloride by product converter and the rotary drum reactor for deposition of silicon from trichlorosilane. The design criteria of the initial laboratory equipment included consideration of the reaction chemistry, thermodynamics, and other technical factors. Design and construction of the laboratory equipment was completed. Preliminary silicon tetrachloride conversion experiments confirmed the expected high yield of trichlorosilane, up to 98 percent of theoretical conversion. A preliminary solar-grade polysilicon cost estimate, including capital costs considered extremely conservative, of $6.91/kg supports the potential of this approach to achieve the cost goal. The closed cycle process appears to have a very likely potential to achieve LSA goals.
An audit of diabetes care at 3 centres in Alexandria.
Abou El-Enein, N Y; Abolfotouh, M A
2008-01-01
Selected indicators for structure, process and outcome of care were used to audit diabetes care in 3 centres in Alexandria. Structure was poor: main problems included absence of appointment and recall system, deficiencies in laboratory resources and lack of educational material. Process of care was poor for 69.2% of patients: deficiencies included absence of essential information in records and missing some essential clinical examinations. Degree of control was poor for 49.2% of patients and only 30.6% had no complications. Compliance to appointment was good for about 80% of patients. Better outcome (fewer complications and higher compliance) was significantly associated with poor process of care. This cannot, however, be considered a valid predictor of outcome as good care might be initiated by the presence of complications.
Stochastic differential equations and turbulent dispersion
NASA Technical Reports Server (NTRS)
Durbin, P. A.
1983-01-01
Aspects of the theory of continuous stochastic processes that seem to contribute to an understanding of turbulent dispersion are introduced and the theory and philosophy of modelling turbulent transport is emphasized. Examples of eddy diffusion examined include shear dispersion, the surface layer, and channel flow. Modeling dispersion with finite-time scale is considered including the Langevin model for homogeneous turbulence, dispersion in nonhomogeneous turbulence, and the asymptotic behavior of the Langevin model for nonhomogeneous turbulence.
NASA Technical Reports Server (NTRS)
Bierman, G. J.
1975-01-01
Square root information estimation, starting from its beginnings in least-squares parameter estimation, is considered. Special attention is devoted to discussions of sensitivity and perturbation matrices, computed solutions and their formal statistics, consider-parameters and consider-covariances, and the effects of a priori statistics. The constant-parameter model is extended to include time-varying parameters and process noise, and the error analysis capabilities are generalized. Efficient and elegant smoothing results are obtained as easy consequences of the filter formulation. The value of the techniques is demonstrated by the navigation results that were obtained for the Mariner Venus-Mercury (Mariner 10) multiple-planetary space probe and for the Viking Mars space mission.
Straightening of a wavy strip: An elastic-plastic contact problem including snap-through
NASA Technical Reports Server (NTRS)
Fischer, D. F.; Rammerstorfer, F. G.
1980-01-01
The nonlinear behavior of a wave like deformed metal strip during the levelling process were calculated. Elastic-plastic material behavior as well as nonlinearities due to large deformations were considered. The considered problem lead to a combined stability and contact problem. It is shown that, despite the initially concentrated loading, neglecting the change of loading conditions due to altered contact domains may lead to a significant error in the evaluation of the nonlinear behavior and particularly to an underestimation of the stability limit load. The stability was examined by considering the load deflection path and the behavior of a load-dependent current stiffness parameter in combination with the determinant of the current stiffness matrix.
Alteration processes of alkenones and related lipids in water columns and sediments
NASA Astrophysics Data System (ADS)
Harvey, H. Rodger
2000-08-01
Alkenones produced by the haptophyte algae are currently being used as indices of sea surface temperature in recent and past ocean environments, but limited information is available concerning the impact of biotic and abiotic processes on the integrity of these long chain lipids. This synthesis provides selected background information on major alteration processes that must be considered before such indices can be used with confidence. A number of processes in the water column and surface sediments have the potential to impact the structural integrity of alkenones and compromise their ability as temperature markers. Processes discussed include the alteration of alkenone structure during early diagenesis, direct biotic and abiotic impacts, and the effect of digestive processes by grazers. Current literature suggests that despite substantial changes in concentration from biological processing, the temperature signal is preserved. For each of these processes, information on the integrity of the alkenone isotopic signature is also needed and limited information available is reviewed. In addition to the alkenones, related lipids including the long chain alkadienes and akyl alkenoates that might serve as ancillary markers are discussed.
NASA Technical Reports Server (NTRS)
Kennedy, J. R.; Fitzpatrick, W. S.
1971-01-01
The computer executive functional system design concepts derived from study of the Space Station/Base are presented. Information Management System hardware configuration as directly influencing the executive design is reviewed. The hardware configuration and generic executive design requirements are considered in detail in a previous report (System Configuration and Executive Requirements Specifications for Reusable Shuttle and Space Station/Base, 9/25/70). This report defines basic system primitives and delineates processes and process control. Supervisor states are considered for describing basic multiprogramming and multiprocessing systems. A high-level computer executive including control of scheduling, allocation of resources, system interactions, and real-time supervisory functions is defined. The description is oriented to provide a baseline for a functional simulation of the computer executive system.
An assessment of space shuttle flight software development processes
NASA Technical Reports Server (NTRS)
1993-01-01
In early 1991, the National Aeronautics and Space Administration's (NASA's) Office of Space Flight commissioned the Aeronautics and Space Engineering Board (ASEB) of the National Research Council (NRC) to investigate the adequacy of the current process by which NASA develops and verifies changes and updates to the Space Shuttle flight software. The Committee for Review of Oversight Mechanisms for Space Shuttle Flight Software Processes was convened in Jan. 1992 to accomplish the following tasks: (1) review the entire flight software development process from the initial requirements definition phase to final implementation, including object code build and final machine loading; (2) review and critique NASA's independent verification and validation process and mechanisms, including NASA's established software development and testing standards; (3) determine the acceptability and adequacy of the complete flight software development process, including the embedded validation and verification processes through comparison with (1) generally accepted industry practices, and (2) generally accepted Department of Defense and/or other government practices (comparing NASA's program with organizations and projects having similar volumes of software development, software maturity, complexity, criticality, lines of code, and national standards); (4) consider whether independent verification and validation should continue. An overview of the study, independent verification and validation of critical software, and the Space Shuttle flight software development process are addressed. Findings and recommendations are presented.
ON THE DYNAMICAL DERIVATION OF EQUILIBRIUM STATISTICAL MECHANICS
DOE Office of Scientific and Technical Information (OSTI.GOV)
Prigogine, I.; Balescu, R.; Henin, F.
1960-12-01
Work on nonequilibrium statistical mechanics, which allows an extension of the kinetic proof to all results of equilibrium statistical mechanics involving a finite number of degrees of freedom, is summarized. As an introduction to the general N-body problem, the scattering theory in classical mechanics is considered. The general N-body problem is considered for the case of classical mechanics, quantum mechanics with Boltzmann statistics, and quantum mechanics including quantum statistics. Six basic diagrams, which describe the elementary processes of the dynamics of correlations, were obtained. (M.C.G.)
Evaluating group purchasing organizations.
Kaldor, Dennis C; Kowalski, Jamie C; Tankersley, Mark A
2003-01-01
A formal evaluation process can help healthcare organizations assess the current and/or potential value of a group purchasing organization (GPO). Healthcare organizations should approach a GPO evaluation as if they were entering into a new relationship. The evaluation should include purchasing and financial services, value-added services, and corporate relations/business practices. Healthcare organizations should consider the potential economies of scale and other services offered by a GPO. Healthcare organizations should consider using acceptable substitutes for products currently used or seeking products through alternative sources if doing so achieves greater value.
Incorporating Edge Information into Best Merge Region-Growing Segmentation
NASA Technical Reports Server (NTRS)
Tilton, James C.; Pasolli, Edoardo
2014-01-01
We have previously developed a best merge region-growing approach that integrates nonadjacent region object aggregation with the neighboring region merge process usually employed in region growing segmentation approaches. This approach has been named HSeg, because it provides a hierarchical set of image segmentation results. Up to this point, HSeg considered only global region feature information in the region growing decision process. We present here three new versions of HSeg that include local edge information into the region growing decision process at different levels of rigor. We then compare the effectiveness and processing times of these new versions HSeg with each other and with the original version of HSeg.
Eagle's syndrome associated with lingual nerve paresthesia: a case report.
Dong, Zhiwei; Bao, Haihong; Zhang, Li; Hua, Zequan
2014-05-01
Eagle's syndrome is characterized by a variety of symptoms, including throat pain, sensation of a foreign body in the pharynx, dysphagia, referred otalgia, and neck and throat pain exacerbated by head rotation. Any styloid process longer than 25 mm should be considered elongated and will usually be responsible for Eagle's syndrome. Surgical resection of the elongated styloid is a routine treatment and can be accomplished using a transoral or an extraoral approach. We report a patient with a rare giant styloid process that was approximately 81.7 mm. He complained of a rare symptom: hemitongue paresthesia. After removal of the elongated styloid process using the extraoral approach, his symptoms, including the hemitongue paresthesia, were alleviated. We concluded that if the styloid process displays medium to severe elongation, the extraoral approach will be appropriate. Copyright © 2014 American Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc. All rights reserved.
Continuous Manufacturing of Recombinant Therapeutic Proteins: Upstream and Downstream Technologies.
Patil, Rohan; Walther, Jason
2017-03-07
Continuous biomanufacturing of recombinant therapeutic proteins offers several potential advantages over conventional batch processing, including reduced cost of goods, more flexible and responsive manufacturing facilities, and improved and consistent product quality. Although continuous approaches to various upstream and downstream unit operations have been considered and studied for decades, in recent years interest and application have accelerated. Researchers have achieved increasingly higher levels of process intensification, and have also begun to integrate different continuous unit operations into larger, holistically continuous processes. This review first discusses approaches for continuous cell culture, with a focus on perfusion-enabling cell separation technologies including gravitational, centrifugal, and acoustic settling, as well as filtration-based techniques. We follow with a review of various continuous downstream unit operations, covering categories such as clarification, chromatography, formulation, and viral inactivation and filtration. The review ends by summarizing case studies of integrated and continuous processing as reported in the literature.
Consumers' conceptualization of ultra-processed foods.
Ares, Gastón; Vidal, Leticia; Allegue, Gimena; Giménez, Ana; Bandeira, Elisa; Moratorio, Ximena; Molina, Verónika; Curutchet, María Rosa
2016-10-01
Consumption of ultra-processed foods has been associated with low diet quality, obesity and other non-communicable diseases. This situation makes it necessary to develop educational campaigns to discourage consumers from substituting meals based on unprocessed or minimally processed foods by ultra-processed foods. In this context, the aim of the present work was to investigate how consumers conceptualize the term ultra-processed foods and to evaluate if the foods they perceive as ultra-processed are in concordance with the products included in the NOVA classification system. An online study was carried out with 2381 participants. They were asked to explain what they understood by ultra-processed foods and to list foods that can be considered ultra-processed. Responses were analysed using inductive coding. The great majority of the participants was able to provide an explanation of what ultra-processed foods are, which was similar to the definition described in the literature. Most of the participants described ultra-processed foods as highly processed products that usually contain additives and other artificial ingredients, stressing that they have low nutritional quality and are unhealthful. The most relevant products for consumers' conceptualization of the term were in agreement with the NOVA classification system and included processed meats, soft drinks, snacks, burgers, powdered and packaged soups and noodles. However, some of the participants perceived processed foods, culinary ingredients and even some minimally processed foods as ultra-processed. This suggests that in order to accurately convey their message, educational campaigns aimed at discouraging consumers from consuming ultra-processed foods should include a clear definition of the term and describe some of their specific characteristics, such as the type of ingredients included in their formulation and their nutritional composition. Copyright © 2016 Elsevier Ltd. All rights reserved.
DOE Office of Scientific and Technical Information (OSTI.GOV)
MacKinnon, R.J.; Sullivan, T.M.; Kinsey, R.R.
1997-05-01
The BLT-EC computer code has been developed, implemented, and tested. BLT-EC is a two-dimensional finite element computer code capable of simulating the time-dependent release and reactive transport of aqueous phase species in a subsurface soil system. BLT-EC contains models to simulate the processes (container degradation, waste-form performance, transport, chemical reactions, and radioactive production and decay) most relevant to estimating the release and transport of contaminants from a subsurface disposal system. Water flow is provided through tabular input or auxiliary files. Container degradation considers localized failure due to pitting corrosion and general failure due to uniform surface degradation processes. Waste-form performancemore » considers release to be limited by one of four mechanisms: rinse with partitioning, diffusion, uniform surface degradation, and solubility. Transport considers the processes of advection, dispersion, diffusion, chemical reaction, radioactive production and decay, and sources (waste form releases). Chemical reactions accounted for include complexation, sorption, dissolution-precipitation, oxidation-reduction, and ion exchange. Radioactive production and decay in the waste form is simulated. To improve the usefulness of BLT-EC, a pre-processor, ECIN, which assists in the creation of chemistry input files, and a post-processor, BLTPLOT, which provides a visual display of the data have been developed. BLT-EC also includes an extensive database of thermodynamic data that is also accessible to ECIN. This document reviews the models implemented in BLT-EC and serves as a guide to creating input files and applying BLT-EC.« less
Implementation of a longitudinal mentored scholarly project: an approach at two medical schools.
Boninger, Michael; Troen, Philip; Green, Emily; Borkan, Jeffrey; Lance-Jones, Cynthia; Humphrey, Allen; Gruppuso, Philip; Kant, Peter; McGee, James; Willochell, Michael; Schor, Nina; Kanter, Steven L; Levine, Arthur S
2010-03-01
An increasing number of medical schools have implemented or are considering implementing scholarly activity programs as part of their undergraduate medical curricula. The goal of these programs is to foster students' analytical skills, enhance their self-directed learning and their oral and written communication skills, and ultimately to train better physicians. In this article, the authors describe the approach to implementing scholarly activities at a school that requires this activity and at a school where it is elective. Both programs have dealt with significant challenges including orienting students to a complex activity that is fundamentally different than traditional medical school courses and clerkships, helping both students and their mentors understand how to "stay on track" and complete work, especially during the third and fourth years, and educating students and mentors about the responsible conduct of research, especially involving human participants. Both schools have found the implementation process to be evolutionary, requiring experience before faculty could significantly improve processes. A required scholarly activity has highlighted the need for information technology (IT) support, including Web-based document storage and student updates, as well as automatic e-mails alerting supervisory individuals to student activity. Directors of the elective program have found difficulty with both ensuring uniform outcomes across different areas of study and leadership changes in a process that has been largely student-driven. Both programs have found that teamwork, regular meetings, and close communication have helped with implementation. Schools considering the establishment of a scholarly activity should consider these factors when designing programs.
NASA Technical Reports Server (NTRS)
Spurlock, J. M.
1975-01-01
Promising candidate designs currently being considered for the management of spacecraft solid waste and waste-water materials were assessed. The candidate processes were: (1) the radioisotope thermal energy evaporation/incinerator process; (2) the dry incineration process; and (3) the wet oxidation process. The types of spacecraft waste materials that were included in the base-line computational input to the candidate systems were feces, urine residues, trash and waste-water concentrates. The performance characteristics and system requirements for each candidate process to handle this input and produce the specified acceptable output (i.e., potable water, a storable dry ash, and vapor phase products that can be handled by a spacecraft atmosphere control system) were estimated and compared. Recommendations are presented.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Koopman, D.
2011-07-14
A program was conducted to systematically evaluate potential impacts of the proposed Small Column Ion Exchange (SCIX) process on the Defense Waste Processing Facility (DWPF) Chemical Processing Cell (CPC). The program involved a series of interrelated tasks. Past studies of the impact of crystalline silicotitanate (CST) and monosodium titanate (MST) on DWPF were reviewed. Paper studies and material balance calculations were used to establish reasonable bounding levels of CST and MST in sludge. Following the paper studies, Sludge Batch 10 (SB10) simulant was modified to have both bounding and intermediate levels of MST and ground CST. The SCIX flow sheetmore » includes grinding of the CST which is larger than DWPF frit when not ground. Nominal ground CST was not yet available, therefore a similar CST ground previously in Savannah River National Laboratory (SRNL) was used. It was believed that this CST was over ground and that it would bound the impact of nominal CST on sludge slurry properties. Lab-scale simulations of the DWPF CPC were conducted using SB10 simulants with no, intermediate, and bounding levels of CST and MST. Tests included both the Sludge Receipt and Adjustment Tank (SRAT) and Slurry Mix Evaporator (SME) cycles. Simulations were performed at high and low acid stoichiometry. A demonstration of the extended CPC flowsheet was made that included streams from the site interim salt processing operations. A simulation using irradiated CST and MST was also completed. An extensive set of rheological measurements was made to search for potential adverse consequences of CST and MST and slurry rheology in the CPC. The SCIX CPC impact program was conducted in parallel with a program to evaluate the impact of SCIX on the final DWPF glass waste form and on the DWPF melter throughput. The studies must be considered together when evaluating the full impact of SCIX on DWPF. Due to the fact that the alternant flowsheet for DWPF has not been selected, this study did not consider the impact of proposed future alternative DWPF CPC flowsheets. The impact of the SCIX streams on DWPF processing using the selected flowsheet need to be considered as part of the technical baseline studies for coupled processing with the selected flowsheet. In addition, the downstream impact of aluminum dissolution on waste containing CST and MST has not yet been evaluated. The current baseline would not subject CST to the aluminum dissolution process and technical concerns with performing the dissolution with CST have been expressed. Should this option become feasible, the downstream impact should be considered. The main area of concern for DWPF from aluminum dissolution is an impact on rheology. The SCIX project is planning for SRNL to complete MST, CST, and sludge rheology testing to evaluate any expected changes. The impact of ground CST transport and flush water on the DWPF CPC feed tank (and potential need for decanting) has not been defined or studied.« less
NASA Astrophysics Data System (ADS)
Postigo-Boix, Marcos; Melús-Moreno, José L.
2018-04-01
Mobile Network Operators (MNOs) present wireless services of the same kind in identical zones, clients select the service taking into account any element they consider relevant. Churning hits on the design of the network and the method to assign prices by MNOs, and of course their earnings. Therefore, MNOs try to reduce churn detecting potential churners before they leave the service. Our approach to churn prediction considers each customer individually. Previous research shows that members of the social circle of a subscriber may influence churn. Thus, many scenarios that describe social relations, and in which churning processes could be expected, set an emerging challenge with practical implications. This paper uses the Agent-Based Modeling (ABM) technique to model customers. The model's parameters include demographic and psychographic features as well as usage profiles according to their social behavior considering their customers' profiles. Our model modifies and extends an existing real social network generator algorithm that considers customer's profiles and homophily considerations to create connections. We show that using our approach, groups of customers with greater tendency to churn due to the influence of their social networks can be identified better.
Making a move in exercise referral: co-development of a physical activity referral scheme.
Buckley, B J R; Thijssen, D H J; Murphy, R C; Graves, L E F; Whyte, G; Gillison, F B; Crone, D; Wilson, P M; Watson, P M
2018-04-24
Translational research is required to ensure exercise referral schemes (ERSs) are evidence-based and reflect local needs. This article reports process data from the co-development phase of an ERS, providing an insight into (i) factors that must be considered when translating evidence to practice in an ERS setting, and (ii) challenges and facilitators of conducting participatory research involving multiple stakeholders. An ERS was iteratively co-developed by a multidisciplinary stakeholder group (commissioners, managers, practitioners, patients and academics) via five participatory meetings and an online survey. Audio data (e.g. group discussions) and visual data (e.g. whiteboard notes) were recorded and analysed using NVivo-10 electronic software. Factors to consider when translating evidence to practice in an ERS setting included (i) current ERS culture; (ii) skills, safety and accountability; and (iii) resources and capacity. The co-development process was facilitated by needs-analysis, open questions, multidisciplinary debate and reflective practice. Challenges included contrasting views, irregular attendance and (mis)perceptions of evaluation. The multidisciplinary co-development process highlighted cultural and pragmatic issues related to exercise referral provision, resulting in an evidence-based intervention framework designed to be implemented within existing infrastructures. Further work is required to establish the feasibility and effectiveness of the co-developed intervention in practice.
Obsidianus lapis rugosity and hardness determination: fibre laser craftsmanship
NASA Astrophysics Data System (ADS)
Aguilar-Morales, A. I.; Velazquez-Gonzalez, J. S.; Marrujo-García, S.; Reyes-Sanchez, J. I.; Alvarez-Chávez, J. A.
2014-05-01
Obsidianus lapis is a volcanic rock that has been worked into tools for cutting or weaponry by Teotihuacan people for hundreds of years. Currently it is used in jewelry or for house decorative items such as elaborated sculptures. From the physico-chemical properties point of view, obsidianus lapis is considered a glass as its composition is 80% silicon dioxide. In México there are different kinds of obsidianus lapis according to its colour: rainbow, black, brown, red, silver, golden and snowflake. The traditional grinding process for working with obsidianus lapis includes fixed grinders and sandpaper for the polishing process, where the craftsman grinds the rock manually obtaining a variety of shapes. Laser processing of natural stones is a relatively new topic. We propose the use of an Yb3+-doped fibre laser for cutting and ablating obsidianus lapis into spherical, rectangular and oval shapes. By means of a theoretical analysis of roughness and hardness, which affect the different surfaces and final shapes, and considering the changes in material temperature during laser interaction, this work will focus on parameter determination such as: laser fluence, incidence angle, laser average power and peak pulse energy, from the proposed Q-switched fibre laser design. Full optical, hardness and rugosity, initial and final, characterization will be included in the presentation.
Framework for the quality assurance of 'omics technologies considering GLP requirements.
Kauffmann, Hans-Martin; Kamp, Hennicke; Fuchs, Regine; Chorley, Brian N; Deferme, Lize; Ebbels, Timothy; Hackermüller, Jörg; Perdichizzi, Stefania; Poole, Alan; Sauer, Ursula G; Tollefsen, Knut E; Tralau, Tewes; Yauk, Carole; van Ravenzwaay, Ben
2017-12-01
'Omics technologies are gaining importance to support regulatory toxicity studies. Prerequisites for performing 'omics studies considering GLP principles were discussed at the European Centre for Ecotoxicology and Toxicology of Chemicals (ECETOC) Workshop Applying 'omics technologies in Chemical Risk Assessment. A GLP environment comprises a standard operating procedure system, proper pre-planning and documentation, and inspections of independent quality assurance staff. To prevent uncontrolled data changes, the raw data obtained in the respective 'omics data recording systems have to be specifically defined. Further requirements include transparent and reproducible data processing steps, and safe data storage and archiving procedures. The software for data recording and processing should be validated, and data changes should be traceable or disabled. GLP-compliant quality assurance of 'omics technologies appears feasible for many GLP requirements. However, challenges include (i) defining, storing, and archiving the raw data; (ii) transparent descriptions of data processing steps; (iii) software validation; and (iv) ensuring complete reproducibility of final results with respect to raw data. Nevertheless, 'omics studies can be supported by quality measures (e.g., GLP principles) to ensure quality control, reproducibility and traceability of experiments. This enables regulators to use 'omics data in a fit-for-purpose context, which enhances their applicability for risk assessment. Copyright © 2017 Elsevier Inc. All rights reserved.
ES1 is a mitochondrial enlarging factor contributing to form mega-mitochondria in zebrafish cones.
Masuda, Takamasa; Wada, Yasutaka; Kawamura, Satoru
2016-03-01
Total mass of mitochondria increases during cell proliferation and differentiation through mitochondrial biogenesis, which includes mitochondrial proliferation and growth. During the mitochondrial growth, individual mitochondria have been considered to be enlarged independently of mitochondrial fusion. However, molecular basis for this enlarging process has been poorly understood. Cone photoreceptor cells in the retina possess large mitochondria, so-called mega-mitochondria that have been considered to arise via the enlarging process. Here we show that ES1 is a novel mitochondria-enlarging factor contributing to form mega-mitochondria in cones. ES1 is specifically expressed in cones and localized to mitochondria including mega-mitochondria. Knockdown of ES1 markedly reduced the mitochondrial size in cones. In contrast, ectopic expression of ES1 in rods significantly increased both the size of individual mitochondria and the total mass of the mitochondrial cluster without changing the number of them. RNA-seq analysis showed that ERRα and its downstream mitochondrial genes were significantly up-regulated in the ES1-expressing rods, suggesting facilitation of mitochondrial enlargement via ERRα-dependent processes. Furthermore, higher energy state was detected in the ES1-expressing rods, indicating that the enlarged mitochondria by ES1 are capable of producing high energy. ES1 is the mitochondrial protein that is first found to promote enlargement of individual mitochondria.
Preparation of composite materials in space. Volume 2: Technical report
NASA Technical Reports Server (NTRS)
Steurer, W. H.; Kaye, S.
1973-01-01
A study to define promising materials, significant processing criteria, and the related processing techniques and apparatus for the preparation of composite materials in space was conducted. The study also established a program for zero gravity experiments and the required developmental efforts. The following composite types were considered: (1) metal-base fiber and particle composites, including cemented compacts, (2) controlled density metals, comprising plain and reinforced metal foams, and (3) unidirectionally solidified eutectic alloys. A program of suborbital and orbital experiments for the 1972 to 1978 time period was established to identify materials, processes, and required experiment equipment.
Advanced imaging programs: maximizing a multislice CT investment.
Falk, Robert
2008-01-01
Advanced image processing has moved from a luxury to a necessity in the practice of medicine. A hospital's adoption of sophisticated 3D imaging entails several important steps with many factors to consider in order to be successful. Like any new hospital program, 3D post-processing should be introduced through a strategic planning process that includes administrators, physicians, and technologists to design, implement, and market a program that is scalable-one that minimizes up front costs while providing top level service. This article outlines the steps for planning, implementation, and growth of an advanced imaging program.
Fuel quality/processing study. Volume 4: On site processing studies
NASA Technical Reports Server (NTRS)
Jones, G. E., Jr.; Cutrone, M.; Doering, H.; Hickey, J.
1981-01-01
Fuel treated at the turbine and the turbine exhaust gas processed at the turbine site are studied. Fuel treatments protect the turbine from contaminants or impurities either in the upgrading fuel as produced or picked up by the fuel during normal transportation. Exhaust gas treatments provide for the reduction of NOx and SOx to environmentally acceptable levels. The impact of fuel quality upon turbine maintenance and deterioration is considered. On site costs include not only the fuel treatment costs as such, but also incremental costs incurred by the turbine operator if a turbine fuel of low quality is not acceptably upgraded.
The growth receptors and their role in wound healing.
Rolfe, Kerstin J; Grobbelaar, Adriaan O
2010-11-01
Abnormal wound healing is a major problem in healthcare today, with both scarring and chronic wounds affecting large numbers of individuals worldwide. Wound healing is a complex process involving several variables, including growth factors and their receptors. Chronic wounds fail to complete the wound healing process, while scarring is considered to be an overzealous wound healing process. Growth factor receptors and their ligands are being investigated to assess their potential in the development of therapeutic strategies to improve wound healing. This review discusses potential therapeutics for manipulating growth factors and their corresponding receptors for the treatment of abnormal wound healing.
Secondary School Teachers' Approaches to Teaching Composition Using Digital Technology
ERIC Educational Resources Information Center
Wise, Stuart
2016-01-01
The music industry in the 21 century uses digital technology in a wide range of applications including in performance, in composition and in recording and publishing. In this article, I consider how the impact of digital technologies may be affecting pedagogical processes adopted by secondary music teachers, particularly in the area of…
The Measurement and Cost of Removing Unexplained Gender Differences in Faculty Salaries.
ERIC Educational Resources Information Center
Becker, William E.; Toutkoushian, Robert K.
1995-01-01
In assessing sex-discrimination suit damages, debate rages over the type and number of variables included in a single-equation model of the salary-determination process. This article considers single- and multiple-equation models, providing 36 different damage calculations. For University of Minnesota data, equalization cost hinges on the…
The Two Brains and the Education Process.
ERIC Educational Resources Information Center
Shook, Ronald
The human brain is lateralized, different functions being housed in each hemisphere. Several assumptions which are mistakenly considered fact by researchers include: (1) the left hemisphere is for rational functions, while the right is for intuitive functions; (2) the hemispheres do not interact as well with each other as they should; (3) the use…
The Communicative Arts: An Introduction to Mass Media.
ERIC Educational Resources Information Center
Steinberg, Charles S.
All areas of mass communication are surveyed. Man's earliest efforts as a communicator are considered, and what is known about the development of speech and writing is explored. Various theories (including mathematical ones) are reviewed which attempt to explain the processes of both personal and mass communication. Separate chapters focus on the…
Factors to Consider in Designing Aerosol Inlet Systems for Engine Exhaust Plume Sampling
NASA Technical Reports Server (NTRS)
Anderson, Bruce
2004-01-01
This document consists of viewgraphs of charts and diagrams of considerations to take when sampling the engine exhaust plume. It includes a chart that compares the emissions from various fuels, a diagram and charts of the various processes and conditions that influence the particulate size and concentration,
Federal Register 2010, 2011, 2012, 2013, 2014
2011-08-26
... (ADAMS), which provides text and image files of the NRC's public documents in the NRC Library at http... considered, but eliminated from detailed analysis, include conventional uranium mining and milling, conventional mining and heap leach processing, alternate lixiviants, and alternative wastewater disposal...
40 CFR Appendix A to Subpart K of... - Criteria for evaluating a State's proposed NEPA-Like process
Code of Federal Regulations, 2014 CFR
2014-07-01
... SERP will adequately consider: (1) Designation of a study area comparable to the final system; (2) A...) Present and future conditions; (5) Land use and other social parameters including recreation and open... (residential, commercial, institutional and industrial) within the project study area; and (8) Other...
40 CFR Appendix A to Subpart K of... - Criteria for evaluating a State's proposed NEPA-Like process
Code of Federal Regulations, 2011 CFR
2011-07-01
... SERP will adequately consider: (1) Designation of a study area comparable to the final system; (2) A...) Present and future conditions; (5) Land use and other social parameters including recreation and open... (residential, commercial, institutional and industrial) within the project study area; and (8) Other...
40 CFR Appendix A to Subpart L - Criteria for Evaluating a State's Proposed NEPA-Like Process
Code of Federal Regulations, 2012 CFR
2012-07-01
... consider: (1) Designation of a study area comparable to the final system; (2) A range of feasible... conditions; (5) Land use and other social parameters including relevant recreation and open-space..., institutional, and industrial) within the project study area; and (8) Other anticipated public works projects...
40 CFR Appendix A to Subpart L - Criteria for Evaluating a State's Proposed NEPA-Like Process
Code of Federal Regulations, 2010 CFR
2010-07-01
... consider: (1) Designation of a study area comparable to the final system; (2) A range of feasible... conditions; (5) Land use and other social parameters including relevant recreation and open-space..., institutional, and industrial) within the project study area; and (8) Other anticipated public works projects...
40 CFR Appendix A to Subpart L of... - Criteria for Evaluating a State's Proposed NEPA-Like Process
Code of Federal Regulations, 2013 CFR
2013-07-01
... the SERP will adequately consider: (1) Designation of a study area comparable to the final system; (2... impacts; (4) Present and future conditions; (5) Land use and other social parameters including relevant... (residential, commercial, institutional, and industrial) within the project study area; and (8) Other...
40 CFR Appendix A to Subpart K of... - Criteria for evaluating a State's proposed NEPA-Like process
Code of Federal Regulations, 2012 CFR
2012-07-01
... SERP will adequately consider: (1) Designation of a study area comparable to the final system; (2) A...) Present and future conditions; (5) Land use and other social parameters including recreation and open... (residential, commercial, institutional and industrial) within the project study area; and (8) Other...
40 CFR Appendix A to Subpart K of... - Criteria for evaluating a State's proposed NEPA-Like process
Code of Federal Regulations, 2010 CFR
2010-07-01
... SERP will adequately consider: (1) Designation of a study area comparable to the final system; (2) A...) Present and future conditions; (5) Land use and other social parameters including recreation and open... (residential, commercial, institutional and industrial) within the project study area; and (8) Other...
40 CFR Appendix A to Subpart K of... - Criteria for evaluating a State's proposed NEPA-Like process
Code of Federal Regulations, 2013 CFR
2013-07-01
... SERP will adequately consider: (1) Designation of a study area comparable to the final system; (2) A...) Present and future conditions; (5) Land use and other social parameters including recreation and open... (residential, commercial, institutional and industrial) within the project study area; and (8) Other...
40 CFR Appendix A to Subpart L of... - Criteria for Evaluating a State's Proposed NEPA-Like Process
Code of Federal Regulations, 2014 CFR
2014-07-01
... the SERP will adequately consider: (1) Designation of a study area comparable to the final system; (2... impacts; (4) Present and future conditions; (5) Land use and other social parameters including relevant... (residential, commercial, institutional, and industrial) within the project study area; and (8) Other...
40 CFR Appendix A to Subpart L - Criteria for Evaluating a State's Proposed NEPA-Like Process
Code of Federal Regulations, 2011 CFR
2011-07-01
... consider: (1) Designation of a study area comparable to the final system; (2) A range of feasible... conditions; (5) Land use and other social parameters including relevant recreation and open-space..., institutional, and industrial) within the project study area; and (8) Other anticipated public works projects...
ERIC Educational Resources Information Center
Pilz, Matthias
2012-01-01
This article considers the modularisation of initial vocational training (including apprenticeships) as a modernisation strategy in Germany, Austria and Switzerland. Training systems are similarly structured in these three countries with the apprenticeship system at their heart, and the three national philosophies of education and training are…
Michael Eisenberg and Robert Berkowitz's Big6[TM] Information Problem-Solving Model.
ERIC Educational Resources Information Center
Carey, James O.
2003-01-01
Reviews the Big6 information problem-solving model. Highlights include benefits and dangers of the simplicity of the model; theories of instruction; testing of the model; the model as a process for completing research projects; and advice for school library media specialists considering use of the model. (LRW)
ERIC Educational Resources Information Center
Maynard, Jennifer Leigh
2012-01-01
Emphasis on regular mathematics skill assessment, intervention, and progress monitoring under the RTI model has created a need for the development of assessment instruments that are psychometrically sound, reliable, universal, and brief. Important factors to consider when developing or selecting assessments for the school environment include what…
The Need for and Possibility of a Christian Forgiveness Education in Schools
ERIC Educational Resources Information Center
van der Walt, Johannes; de Muynck, Bram; Broer, Nico; Wolhuter, Charl; Potgieter, Ferdinand
2018-01-01
Individuals and communities occasionally need asking and giving forgiveness. Because the process of forgiving is not always well understood, it has become necessary to consider including forgiveness education in school pedagogy and in formal school programs such as Citizenship Education. This possibility is illustrated with examples from South…
Seven Factors You'd Better Not Forget when Changing Attendance Boundaries.
ERIC Educational Resources Information Center
Hyland, Timothy F.
1989-01-01
Redrawing school attendance boundaries is one of the most sensitive tasks a school board faces. Factors to consider include the following: (1) life span of the change; (2) effective date; (3) racial balance; (4) resource equity; and (5) program, public, and financial impact. Outlines a process for developing redistricting plans. (MLF)
NASA Technical Reports Server (NTRS)
Park, Steve
1990-01-01
A large and diverse number of computational techniques are routinely used to process and analyze remotely sensed data. These techniques include: univariate statistics; multivariate statistics; principal component analysis; pattern recognition and classification; other multivariate techniques; geometric correction; registration and resampling; radiometric correction; enhancement; restoration; Fourier analysis; and filtering. Each of these techniques will be considered, in order.
Toward a National Ocean Policy, 1976 and Beyond.
ERIC Educational Resources Information Center
Osgood, Robert E.; And Others
Each chapter in this publication takes up a specific issue, analyzes its importance to the United States, discusses its evolution in the international negotiating process, and considers the various policy options in the context of the treaty making exercise. The criteria for evaluating policy options are included. The eight chapters are: (1) The…
Models for estimation and simulation of crown and canopy cover
John D. Shaw
2005-01-01
Crown width measurements collected during Forest Inventory and Analysis and Forest Health Monitoring surveys are being used to develop individual tree crown width models and plot-level canopy cover models for species and forest types in the Intermountain West. Several model applications are considered in the development process, including remote sensing of plot...
The Budget Process in Parks and Recreation. A Case Study Manual.
ERIC Educational Resources Information Center
Kelsey, Craig; Gray, Howard
This case study manual, designed for undergraduate or graduate students studying the area of parks and recreation fiscal management, considers the practical, critical skills of budgeting techniques. The manual deals with the most common budgeting styles in a step-by-step approach with case study exercises. Each chapter includes an introduction to…
International Student Guide to U.S. Community Colleges, 2007-2008
ERIC Educational Resources Information Center
American Association of Community Colleges (NJ1), 2007
2007-01-01
This guide was produced for prospective students considering studying in the United States. The guide is organized to help students through all stages of the process, including learning about the U.S. higher education system, finding the right college, benefits of attending community college, obtaining a student visa, estimating expenses, living…
Code of Federal Regulations, 2012 CFR
2012-01-01
... available, the planted acres as determined by CCC using other sources. Planted and considered planted (P&CP... the FSA county committee on the farm for a crop. For the purposes of this part, P&CP is limited to... sequence. Replacement crop acreage is not included as P&CP. Processing means with respect to uses of a crop...
Code of Federal Regulations, 2011 CFR
2011-01-01
... available, the planted acres as determined by CCC using other sources. Planted and considered planted (P&CP... the FSA county committee on the farm for a crop. For the purposes of this part P&CP is limited to... sequence. Replacement crop acreage is not included as P&CP. Processing means with respect to uses of a crop...
Code of Federal Regulations, 2013 CFR
2013-01-01
... available, the planted acres as determined by CCC using other sources. Planted and considered planted (P&CP... the FSA county committee on the farm for a crop. For the purposes of this part, P&CP is limited to... sequence. Replacement crop acreage is not included as P&CP. Processing means with respect to uses of a crop...
Code of Federal Regulations, 2014 CFR
2014-01-01
... available, the planted acres as determined by CCC using other sources. Planted and considered planted (P&CP... the FSA county committee on the farm for a crop. For the purposes of this part, P&CP is limited to... sequence. Replacement crop acreage is not included as P&CP. Processing means with respect to uses of a crop...
Proceedings of the 1984 IEEE international conference on systems, man and cybernetics
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
1984-01-01
This conference contains papers on artificial intelligence, pattern recognition, and man-machine systems. Topics considered include concurrent minimization, a robot programming system, system modeling and simulation, camera calibration, thermal power plants, image processing, fault diagnosis, knowledge-based systems, power systems, hydroelectric power plants, expert systems, and electrical transients.
Rotating Biological Contactors (RBC's). Student Manual. Biological Treatment Process Control.
ERIC Educational Resources Information Center
Zickefoose, Charles S.
This student manual provides the textual material for a unit on rotating biological contactors (RBC's). Topic areas considered include: (1) flow patterns of water through RBC installations; (2) basic concepts (shaft and stage); (3) characteristics of biomass; (4) mechanical features (bearings, mechanical drive systems, and air drive systems); (5)…
Many States Include Evolution Questions on Assessments
ERIC Educational Resources Information Center
Cavanagh, Sean
2005-01-01
The theory of evolution, pioneered most famously by Charles Darwin, posits that humans and other living creatures have descended from common ancestors over time through a process of random mutation and natural selection. It is widely considered to be a pillar of modern biology. Over the past year, however, public education has been roiled by…
ERIC Educational Resources Information Center
Ozfidan, Burhan; Machtmes, Krisanna L.; Demir, Husamettin
2014-01-01
Sociocultural theories consider language learning as a social practice examines students as active participants in the construction of learning processes. This study investigates sociocultural theories' central concepts, which includes peer interaction and feedback, private speech, and self-efficacy. The present study is a case study of twenty…
Buying Your Next (or First) PC: What Matters Now?
ERIC Educational Resources Information Center
Crawford, Walt
1993-01-01
Discussion of factors to consider in purchasing a personal computer covers present and future needs, computing environments, memory, processing performance, disk size, and display quality. Issues such as bundled systems, where and when to purchase, and vendor support are addressed; and an annotated bibliography of 28 recent articles is included.…
24 CFR 55.20 - Decision making process.
Code of Federal Regulations, 2011 CFR
2011-04-01
... the affected public is largely non-English speaking. In addition, all notices must be published in an..., including public notices and an examination of practicable alternatives. The steps to be followed in the... public at the earliest possible time of a proposal to consider an action in a floodplain (or in the 500...
Evaluation Method for an App Involving Kitchen Activities.
Burzagli, Laura; Gaggioli, Andrea
2017-01-01
An app, developed for the national Italian project "Design for all", is evaluated here. This app supports the user in most of his/her cooking activities. The evaluation process integrates different technologies, such as expert interview, cognitive walkthrough and focus group, to consider different aspects that include, but are not limited to, usability and accessibility.
Can Videogames Be Used to Develop the Infant Stage Educational Curriculum?
ERIC Educational Resources Information Center
Marín Díaz, Verónica; Martín-Párraga, Javier
2014-01-01
The utilization of videogames is not too common due to their consideration as an element that interferes with the educational and learning process. Thus, few teachers are ready to include videogames as didactic tools. Nevertheless, some educators who consider that they have a potential to become didactic tools are progressively adopting videogames…
The Role of Elaboration in the Comprehension and Retention of Prose: A Critical Review.
ERIC Educational Resources Information Center
Reder, Lynne M.
1980-01-01
Recent research in the area of prose comprehension is reviewed, including factors that affect amount of recall, representations of text structures, and use of world knowledge to aid comprehension. The need for more information processing models of comprehension is emphasized. Elaboration is considered important for comprehension and retention.…
Federal Register 2010, 2011, 2012, 2013, 2014
2012-05-08
... Inspection Service, USDA. ACTION: Final rule. SUMMARY: The Food Safety and Inspection Service (FSIS) is... that outlines a step-by-step reaction process. They also requested that FSIS consider factors such as... to determine more quickly whether a recall action is necessary (including detention and seizure of...
Real Readers for Real Writers.
ERIC Educational Resources Information Center
Dieterich, Dan
In the business writing class, teachers should consider the following suggestions: (1) capture students' interest and involve them, (2) prepare them for life outside the English classroom, (3) help them better understand the writing process, and (4) show them that writing occurs in a context that includes a writer, one or more readers, and a host…
Readings in Computer Based Guidance. The Bartlesville System.
ERIC Educational Resources Information Center
Bartlesville Public Schools, OK.
The document contains six papers which deal with the need for change in guidance and counseling due to the overwhelming amount of data which is insufficiently processed by conventional manual systems. Included in these papers are discussions on when these changes should occur and the nature of their alterations. The reports consider some of the…
The Assayer's Scale: Was Intelligence the Ultimate Currency of the Information Age?
ERIC Educational Resources Information Center
Fuller, Renee
1992-01-01
This article considers the role of the basic cognitive unit, called the "story engram," in young children's learning to read, including children ranging in ability from severe mental retardation to giftedness. It illustrates how the "Ball-Stick-Bird" method of beginning reading can facilitate this process because of the…
Kobayakawa, Mutsutaka; Kawamura, Mitsuru
2011-12-01
Social cognition includes various components of information processing related to communication with other individuals. In this review, we have discussed 3 components of social cognitive function: face recognition, empathy, and decision making. Our social behavior involves recognition based on facial features and also involves empathizing with others; while making decisions, it is important to consider the social consequences of the course of action followed. Face recognition is divided into 2 routes for information processing: a route responsible for overt recognition of the face's identity and a route for emotional and orienting responses based on the face's personal affective significance. Two systems are possibly involved in empathy: a basic emotional contagion "mirroring" system and a more advanced "theory of mind" system that considers the cognitive perspective. Decision making is mediated by a widespread system that includes several cortical and subcortical components. Numerous lesion and neuroimaging studies have contributed to clarifying the neural correlates of social cognitive function, and greater information can be obtained on social cognitive function by combining these 2 approaches.
Incorporating organisational safety culture within ergonomics practice.
Bentley, Tim; Tappin, David
2010-10-01
This paper conceptualises organisational safety culture and considers its relevance to ergonomics practice. Issues discussed in the paper include the modest contribution that ergonomists and ergonomics as a discipline have made to this burgeoning field of study and the significance of safety culture to a systems approach. The relevance of safety culture to ergonomics work with regard to the analysis, design, implementation and evaluation process, and implications for participatory ergonomics approaches, are also discussed. A potential user-friendly, qualitative approach to assessing safety culture as part of ergonomics work is presented, based on a recently published conceptual framework that recognises the dynamic and multi-dimensional nature of safety culture. The paper concludes by considering the use of such an approach, where an understanding of different aspects of safety culture within an organisation is seen as important to the success of ergonomics projects. STATEMENT OF RELEVANCE: The relevance of safety culture to ergonomics practice is a key focus of this paper, including its relationship with the systems approach, participatory ergonomics and the ergonomics analysis, design, implementation and evaluation process. An approach to assessing safety culture as part of ergonomics work is presented.
STUDIES OF METABOLITE-PROTEIN INTERACTIONS: A REVIEW
Matsuda, Ryan; Bi, Cong; Anguizola, Jeanethe; Sobansky, Matthew; Rodriquez, Elliot; Badilla, John Vargas; Zheng, Xiwei; Hage, Benjamin; Hage, David S.
2014-01-01
The study of metabolomics can provide valuable information about biochemical pathways and processes at the molecular level. There have been many reports that have examined the structure, identity and concentrations of metabolites in biological systems. However, the binding of metabolites with proteins is also of growing interest. This review examines past reports that have looked at the binding of various types of metabolites with proteins. An overview of the techniques that have been used to characterize and study metabolite-protein binding is first provided. This is followed by examples of studies that have investigated the binding of hormones, fatty acids, drugs or other xenobiotics, and their metabolites with transport proteins and receptors. These examples include reports that have considered the structure of the resulting solute-protein complexes, the nature of the binding sites, the strength of these interactions, the variations in these interactions with solute structure, and the kinetics of these reactions. The possible effects of metabolic diseases on these processes, including the impact of alterations in the structure and function of proteins, are also considered. PMID:24321277
Glassey, Rachael; O'Connor, Moira; Ives, Angela; Saunders, Christobel; kConFab Investigators; O'Sullivan, Sarah; Hardcastle, Sarah J
2018-05-11
To explore the barriers and experiences of accessing information for women who have received genetic risk assessment/testing results for breast cancer (BC) and are considering a bilateral prophylactic mastectomy (BPM) and, exploring participants' preferences concerning information and support needs. A qualitative retrospective study guided by interpretative phenomenological analysis was utilised. Semi-structured interviews were conducted with forty-six women who were either considering BPM or had already undergone the surgery. Three themes identified barriers to accessing information; difficulties accessing information, inconsistent information and clinical focus/medicalized information. A fourth theme - preferences of information and support needs, identified three subthemes; these were, psychological support, clearly defined processes and photos of mastectomies/reconstruction surgeries. Barriers to accessing information appeared to be widespread. A lack of integrated services contributed to inconsistent information, and medicalized terminology/clinical focus of consultations further complicated understanding. Preferences for information include clearly defined processes, so women know the pathways after confirmation of familial BC risk. Clinical implications include a multidisciplinary team approach, and a protocol that reflects current practice. Copyright © 2018 Elsevier Ltd. All rights reserved.
Electromagnetic Methods of Lightning Detection
NASA Astrophysics Data System (ADS)
Rakov, V. A.
2013-11-01
Both cloud-to-ground and cloud lightning discharges involve a number of processes that produce electromagnetic field signatures in different regions of the spectrum. Salient characteristics of measured wideband electric and magnetic fields generated by various lightning processes at distances ranging from tens to a few hundreds of kilometers (when at least the initial part of the signal is essentially radiation while being not influenced by ionospheric reflections) are reviewed. An overview of the various lightning locating techniques, including magnetic direction finding, time-of-arrival technique, and interferometry, is given. Lightning location on global scale, when radio-frequency electromagnetic signals are dominated by ionospheric reflections, is also considered. Lightning locating system performance characteristics, including flash and stroke detection efficiencies, percentage of misclassified events, location accuracy, and peak current estimation errors, are discussed. Both cloud and cloud-to-ground flashes are considered. Representative examples of modern lightning locating systems are reviewed. Besides general characterization of each system, the available information on its performance characteristics is given with emphasis on those based on formal ground-truth studies published in the peer-reviewed literature.
Some considerations for various positioning systems and their science capabilities
NASA Technical Reports Server (NTRS)
Rey, Charles A.; Merkley, D. R.; Danley, T. J.
1990-01-01
Containerless processing of materials at elevated temperatures is discussed with emphasis on high temperature chemistry, thermophysical properties, materials science, and materials processing. Acoustic and electromagnetic positioning of high temperature melts are discussed. Results from recent ground based experiments, including KC-135 testing of an acoustic levitator, are presented. Some current positioning technologies and the potential for enhancing them are considered. Further, a summary of these technologies and their science capabilities for the development of future experiments is given.
Fractional Brownian motion and long term clinical trial recruitment
Zhang, Qiang; Lai, Dejian
2015-01-01
Prediction of recruitment in clinical trials has been a challenging task. Many methods have been studied, including models based on Poisson process and its large sample approximation by Brownian motion (BM), however, when the independent incremental structure is violated for BM model, we could use fractional Brownian motion to model and approximate the underlying Poisson processes with random rates. In this paper, fractional Brownian motion (FBM) is considered for such conditions and compared to BM model with illustrated examples from different trials and simulations. PMID:26347306
2015-01-01
This editorial introduces the Journal of Applied Psychology. More specifically the editor wants to share with you (a) the journal's scope and mission, (b) expectations for different types of articles considered by the journal, and (c) the review process used. The information included is also based on the editorial team's consideration of current trends in the psychological and organizational sciences, as well as emerging changes in peer review processes within the social sciences. (PsycINFO Database Record (c) 2015 APA, all rights reserved). (c) 2015 APA, all rights reserved.
Fractional Brownian motion and long term clinical trial recruitment.
Zhang, Qiang; Lai, Dejian
2011-05-01
Prediction of recruitment in clinical trials has been a challenging task. Many methods have been studied, including models based on Poisson process and its large sample approximation by Brownian motion (BM), however, when the independent incremental structure is violated for BM model, we could use fractional Brownian motion to model and approximate the underlying Poisson processes with random rates. In this paper, fractional Brownian motion (FBM) is considered for such conditions and compared to BM model with illustrated examples from different trials and simulations.
Irwin, P; Rudd, A
1998-01-01
The emphasis on outcomes measurement requires that casemix is considered in any comparative studies. In 1996 the Intercollegiate Working Party for Stroke agreed a minimum data set to measure the severity of casemix in stroke. The reasons for its development, the evidence base supporting the items included and the possible uses of the data set are described. It is currently being evaluated in national outcome and process audits to be reported at a later date.
Thomas, Kenneth C.; Jones, Eric D.; McBride, Marvin A.
1983-01-01
A process for the fusion welding of nickel alloy steel members wherein a ferrite containing pellet is inserted into a cavity in one member and melted by a welding torch. The resulting weld nugget, a fusion of the nickel containing alloy from the members to be welded and the pellet, has a composition which is sufficiently low in nickel content such that ferrite phases occur within the weld nugget, resulting in improved weld properties. The steel alloys encompassed also include alloys containing carbon and manganese, considered nickel equivalents.
Impact of coastal processes on resource development with an example from Icy Bay, Alaska
Molnia, Bruce F.
1978-01-01
The coastline of Alaska is dynamic and continually readjusting to changes in the many processes that operate in the coastal zone. Because of this dynamic nature, special consideration must be made in planning for development, and. caution must be exercised in site selection for facilities to be emplaced in the coastal zone. All types of coastal processes from continuously active normal processes to the low frequency-high intensity rare event must be considered. Site-specific evaluation-s considering the broad range of possible processes must precede initiation of development. An example of the relation between coastal processes and a proposed resource treatment facility is presented for Icy Bay, Alaska. Icy Bay is the only sheltered bay near many of the offshore tracts leased for petroleum exploration in the 1976 northern Gulf of Alaska OCS (Outer Continental Shelf) lease sale. Consequently, it has been selected as a primary onshore staging site for the support of offshore exploration and development. The environment of Icy Bay has many potentially hazardous features, including a submarine moraine at the bay mouth and actively calving glaciers at the bay's head which produce many icebergs. But most significant from the point of view of locating onshore facilities and pipeline corridors are the high rates of shoreline erosion and sediment deposition. If pipelines or any onshore staging facilities are to be placed in the coastal areas of Icy Bay, then the dynamic changes in shoreline position must be considered so that man-made structures will not be eroded away or be silted in before the completion of development.
Robust crop and weed segmentation under uncontrolled outdoor illumination.
Jeon, Hong Y; Tian, Lei F; Zhu, Heping
2011-01-01
An image processing algorithm for detecting individual weeds was developed and evaluated. Weed detection processes included were normalized excessive green conversion, statistical threshold value estimation, adaptive image segmentation, median filter, morphological feature calculation and Artificial Neural Network (ANN). The developed algorithm was validated for its ability to identify and detect weeds and crop plants under uncontrolled outdoor illuminations. A machine vision implementing field robot captured field images under outdoor illuminations and the image processing algorithm automatically processed them without manual adjustment. The errors of the algorithm, when processing 666 field images, ranged from 2.1 to 2.9%. The ANN correctly detected 72.6% of crop plants from the identified plants, and considered the rest as weeds. However, the ANN identification rates for crop plants were improved up to 95.1% by addressing the error sources in the algorithm. The developed weed detection and image processing algorithm provides a novel method to identify plants against soil background under the uncontrolled outdoor illuminations, and to differentiate weeds from crop plants. Thus, the proposed new machine vision and processing algorithm may be useful for outdoor applications including plant specific direct applications (PSDA).
Methodological considerations for studying social processes.
Patterson, Barbara; Morin, Karen
2012-01-01
To discuss the nature of and considerations in the study of social processes. Social processes include the elements of time, change and human interaction and many phenomena of interest to nurse researchers. Despite the significance of social processes for nursing practice and the labelling in many studies of phenomena as processes, there seems to be an inability to describe processes fully. The paper includes a presentation of two methodological approaches for illuminating the dynamics of social processes: participant observation and prospective time-series designs. Strengths and limitations of the two paradigmatically different approaches are offered. The method an investigator chooses should be considered selectively and appropriately according to the nature of the problem, what is known about the phenomena to be studied, and the investigator's world view and theoretical perspective. The conceptualisation of process can also influence the methodological choice. Capturing a social process in its entirety with either a qualitative or quantitative approach can be a difficult task. The focus of this paper is an initiation and expansion of the dialogue about which methods provide the best insight into social processes. This knowledge may offer opportunities for nurse researchers to design and implement interventions for individuals as they progress through life events.
Mass production of silicon pore optics for ATHENA
NASA Astrophysics Data System (ADS)
Wille, Eric; Bavdaz, Marcos; Collon, Maximilien
2016-07-01
Silicon Pore Optics (SPO) provide high angular resolution with low effective area density as required for the Advanced Telescope for High Energy Astrophysics (Athena). The x-ray telescope consists of several hundreds of SPO mirror modules. During the development of the process steps of the SPO technology, specific requirements of a future mass production have been considered right from the beginning. The manufacturing methods heavily utilise off-the-shelf equipment from the semiconductor industry, robotic automation and parallel processing. This allows to upscale the present production flow in a cost effective way, to produce hundreds of mirror modules per year. Considering manufacturing predictions based on the current technology status, we present an analysis of the time and resources required for the Athena flight programme. This includes the full production process starting with Si wafers up to the integration of the mirror modules. We present the times required for the individual process steps and identify the equipment required to produce two mirror modules per day. A preliminary timeline for building and commissioning the required infrastructure, and for flight model production of about 1000 mirror modules, is presented.
NASA Astrophysics Data System (ADS)
Held, Christian; Liewald, Mathias; Schleich, Ralf; Sindel, Manfred
2010-06-01
The use of lightweight materials offers substantial strength and weight advantages in car body design. Unfortunately such kinds of sheet material are more susceptible to wrinkling, spring back and fracture during press shop operations. For characterization of capability of sheet material dedicated to deep drawing processes in the automotive industry, mainly Forming Limit Diagrams (FLD) are used. However, new investigations at the Institute for Metal Forming Technology have shown that High Strength Steel Sheet Material and Aluminum Alloys show increased formability in case of bending loads are superposed to stretching loads. Likewise, by superposing shearing on in plane uniaxial or biaxial tension formability changes because of materials crystallographic texture. Such mixed stress and strain conditions including bending and shearing effects can occur in deep-drawing processes of complex car body parts as well as subsequent forming operations like flanging. But changes in formability cannot be described by using the conventional FLC. Hence, for purpose of improvement of failure prediction in numerical simulation codes significant failure criteria for these strain conditions are missing. Considering such aspects in defining suitable failure criteria which is easy to implement into FEA a new semi-empirical model has been developed considering the effect of bending and shearing in sheet metals formability. This failure criterion consists of the combination of the so called cFLC (combined Forming Limit Curve), which considers superposed bending load conditions and the SFLC (Shear Forming Limit Curve), which again includes the effect of shearing on sheet metal's formability.
Materials Research for High Speed Civil Transport and Generic Hypersonics-Metals Durability
NASA Technical Reports Server (NTRS)
Schulz, Paul; Hoffman, Daniel
1996-01-01
This report covers a portion of an ongoing investigation of the durability of titanium alloys for the High Speed Civil Transport (HSCT). Candidate alloys need to possess an acceptable combination of properties including strength and toughness as well as fatigue and corrosion resistance when subjected to the HSCT operational environment. These materials must also be capable of being processed into required product forms while maintaining their properties. Processing operations being considered for this airplane include forming, welding, adhesive bonding, and superplastic forming with or without diffusion bonding. This program was designed to develop the material properties database required to lower the risk of using advanced titanium alloys on the HSCT.
Computer imaging and workflow systems in the business office.
Adams, W T; Veale, F H; Helmick, P M
1999-05-01
Computer imaging and workflow technology automates many business processes that currently are performed using paper processes. Documents are scanned into the imaging system and placed in electronic patient account folders. Authorized users throughout the organization, including preadmission, verification, admission, billing, cash posting, customer service, and financial counseling staff, have online access to the information they need when they need it. Such streamlining of business functions can increase collections and customer satisfaction while reducing labor, supply, and storage costs. Because the costs of a comprehensive computer imaging and workflow system can be considerable, healthcare organizations should consider implementing parts of such systems that can be cost-justified or include implementation as part of a larger strategic technology initiative.
Autism, Asthma, Inflammation, and the Hygiene Hypothesis
Becker, Kevin G.
2007-01-01
Inflammation and the genes, molecules, and biological pathways that lead to inflammatory processes influence many important and disparate biological processes and disease states that are quite often not generally considered classical inflammatory or autoimmune disorders. These include development, reproduction, aging, tumor development and tumor rejection, cardiovascular pathologies, metabolic disorders, as well as neurological and psychiatric disorders. This paper compares parallel aspects of autism and inflammatory disorders with an emphasis on asthma. These comparisons include epidemiological, morphometric, molecular, and genetic aspects of both disease types, contributing to a hypothesis of autism in the context of the immune based hygiene hypothesis. This hypothesis is meant to address the apparent rise in the prevalence of autism in the population. PMID:17412520
Perspectives on Home Care Quality
Kane, Rosalie A.; Kane, Robert L.; Illston, Laurel H.; Eustis, Nancy N.
1994-01-01
Home care quality assurance (QA) must consider features inherent in home care, including: multiple goals, limited provider control, and unique family roles. Successive panels of stakeholders were asked to rate the importance of selected home care outcomes. Most highly rated outcomes were freedom from exploitation, satisfaction with care, physical safety, affordability, and physical functioning. Panelists preferred outcome indicators to process and structure, and all groups emphasized “enabling” criteria. Themes highlighted included: interpersonal components of care; normalizing life for clientele; balancing quality of life with safety; developing flexible, negotiated care plans; mechanisms for accountability and case management. These themes were formulated differently according to the stakeholders' role. Providers preferred intermediate outcomes, akin to process. PMID:10140158
Autism, asthma, inflammation, and the hygiene hypothesis.
Becker, Kevin G
2007-01-01
Inflammation and the genes, molecules, and biological pathways that lead to inflammatory processes influence many important and disparate biological processes and disease states that are quite often not generally considered classical inflammatory or autoimmune disorders. These include development, reproduction, aging, tumor development and tumor rejection, cardiovascular pathologies, metabolic disorders, as well as neurological and psychiatric disorders. This paper compares parallel aspects of autism and inflammatory disorders with an emphasis on asthma. These comparisons include epidemiological, morphometric, molecular, and genetic aspects of both disease types, contributing to a hypothesis of autism in the context of the immune based hygiene hypothesis. This hypothesis is meant to address the apparent rise in the prevalence of autism in the population.
NASA Technical Reports Server (NTRS)
1980-01-01
The U.S./Canada wheat/barley exploratory experiment is discussed with emphasis on labeling, machine processing using P1A, and the crop calendar. Classification and the simulated aggregation test used in the U.S. corn/soybean exploratory experiment are also considered. Topics covered regarding the foreign commodity production forecasting project include: (1) the acquisition, handling, and processing of both U.S. and foreign agricultural data, as well as meteorological data. The accuracy assessment methodology, multicrop sampling and aggregation technology development, frame development, the yield project interface, and classification for area estimation are also examined.
Cogeneration Technology Alternatives Study (CTAS). Volume 4: Energy conversion systems
NASA Technical Reports Server (NTRS)
Brown, D. H.; Gerlaugh, H. E.; Priestley, R. R.
1980-01-01
Industrial processes from the largest energy consuming sectors were used as a basis for matching a similar number of energy conversion systems that are considered as candidate which can be made available by the 1985 to 2000 time period. The sectors considered included food, textiles, lumber, paper, chemicals, petroleum, glass, and primary metals. The energy conversion systems included steam and gas turbines, diesels, thermionics, stirling, closed-cycle and steam injected gas turbines, and fuel cells. Fuels considered were coal, both coal and petroleum-based residual and distillate liquid fuels, and low Btu gas obtained through the on-site gasification of coal. An attempt was made to use consistent assumptions and a consistent set of ground rules specified by NASA for determining performance and cost. The advanced and commercially available cogeneration energy conversion systems studied in CTAS are fined together with their performance, capital costs, and the research and developments required to bring them to this level of performance.
Cerri, Karin H; Knapp, Martin; Fernandez, Jose-Luis
2014-09-01
The College Voor Zorgverzekeringen (CVZ) provides guidance to the Dutch healthcare system on funding and use of new pharmaceutical technologies. This study examined the impact of evidence, process and context factors on CVZ decisions in 2004-2009. A data set of CVZ decisions pertaining to pharmaceutical technologies was created, including 29 variables extracted from published information. A three-category outcome variable was used, defined as the decision to 'recommend', 'restrict' or 'not recommend' a technology. Technologies included in list 1A/1B or on the expensive drug list were considered recommended; those included in list 2 or for which patient co-payment is required were considered restricted; technologies not included on any reimbursement list were classified as 'not recommended'. Using multinomial logistic regression, the relative contribution of explanatory variables on CVZ decisions was assessed. In all, 244 technology appraisals (256 technologies) were analysed, with 51%, of technologies recommended, 33% restricted and 16% not recommended by CVZ for funding. The multinomial model showed significant associations (p ≤ 0.10) between CVZ outcome and several variables, including: (1) use of an active comparator and demonstration of statistical superiority of the primary endpoint in clinical trials, (2) pharmaceutical budget impact associated with introduction of the technology, (3) therapeutic indication and (4) prevalence of the target population. Results confirm the value of a comprehensive and multivariate approach to understanding CVZ decision-making.
Gorini, Alessandra; Mazzocco, Ketti; Pravettoni, Gabriella
2015-01-01
Due to the lack of other treatment options, patient candidates for participation in phase I clinical trials are considered the most vulnerable, and many ethical concerns have emerged regarding the informed consent process used in the experimental design of such trials. Starting with these considerations, this nonsystematic review is aimed at analyzing the decision-making processes underlying patients' decision about whether to participate (or not) in phase I trials in order to clarify the cognitive and emotional aspects most strongly implicated in this decision. Considering that there is no uniform decision calculus and that many different variables other than the patient-physician relationship (including demographic, clinical, and personal characteristics) may influence patients' preferences for and processing of information, we conclude that patients' informed decision-making can be facilitated by creating a rigorously developed, calibrated, and validated computer tool modeled on each single patient's knowledge, values, and emotional and cognitive decisional skills. Such a tool will also help oncologists to provide tailored medical information that is useful to improve the shared decision-making process, thereby possibly increasing patient participation in clinical trials. © 2015 S. Karger AG, Basel.
Lambert, Heather C; McColl, Mary Ann; Gilbert, Julie; Wong, Jiahui; Murray, Gale; Shortt, Samuel E D
2005-10-01
The purpose of this study was to describe factors contributing to the decision-making processes of elderly persons as they formulate advance directives in long-term care. This study was qualitative, based on grounded theory. Recruitment was purposive and continued until saturation was reached. Nine residents of a long-term-care facility were interviewed by use of a semistructured format. Open and axial coding of interview transcripts were carried out and the factors contributing to the decision process were defined. Elders based their decisions primarily on information gathered from personal experiences with death and illness. They obtained very little information from professionals or the media. Major factors considered by elders as they weighed information included spiritual, emotional, and social considerations. The factors considered during the decision-making process were oriented more toward the individual's experiences and less on contributions from objective sources than anticipated. Decision making for advance directives is a highly personalized process. The approach of health professionals when assisting with end-of-life decision making should be planned with these contributing factors in mind, so that the services offered to the individuals in this population best meet their needs.
How to do (or not to do)… gender analysis in health systems research.
Morgan, Rosemary; George, Asha; Ssali, Sarah; Hawkins, Kate; Molyneux, Sassy; Theobald, Sally
2016-10-01
Gender-the socially constructed roles, behaviours, activities and attributes that a given society considers appropriate for males, females and other genders-affects how people live, work and relate to each other at all levels, including in relation to the health system. Health systems research (HSR) aims to inform more strategic, effective and equitable health systems interventions, programs and policies; and the inclusion of gender analysis into HSR is a core part of that endeavour. We outline what gender analysis is and how gender analysis can be incorporated into HSR content, process and outcomes Starting with HSR content, i.e. the substantive focus of HSR, we recommend exploring whether and how gender power relations affect females and males in health systems through the use of sex disaggregated data, gender frameworks and questions. Sex disaggregation flags female-male differences or similarities that warrant further analysis; and further analysis is guided by gender frameworks and questions to understand how gender power relations are constituted and negotiated in health systems. Critical aspects of understanding gender power relations include examining who has what (access to resources); who does what (the division of labour and everyday practices); how values are defined (social norms) and who decides (rules and decision-making). Secondly, we examine gender in HSR process by reflecting on how the research process itself is imbued with power relations. We focus on data collection and analysis by reviewing who participates as respondents; when data is collected and where; who is present; who collects data and who analyses data. Thirdly, we consider gender and HSR outcomes by considering who is empowered and disempowered as a result of HSR, including the extent to which HSR outcomes progressively transform gender power relations in health systems, or at least do not further exacerbate them. © The Author 2016. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.
Burr, Tom; Hamada, Michael S.; Howell, John; ...
2013-01-01
Process monitoring (PM) for nuclear safeguards sometimes requires estimation of thresholds corresponding to small false alarm rates. Threshold estimation dates to the 1920s with the Shewhart control chart; however, because possible new roles for PM are being evaluated in nuclear safeguards, it is timely to consider modern model selection options in the context of threshold estimation. One of the possible new PM roles involves PM residuals, where a residual is defined as residual = data − prediction. This paper reviews alarm threshold estimation, introduces model selection options, and considers a range of assumptions regarding the data-generating mechanism for PM residuals.more » Two PM examples from nuclear safeguards are included to motivate the need for alarm threshold estimation. The first example involves mixtures of probability distributions that arise in solution monitoring, which is a common type of PM. The second example involves periodic partial cleanout of in-process inventory, leading to challenging structure in the time series of PM residuals.« less
Role of microglia in glioma biology.
Badie, B; Schartner, J
2001-07-15
Microglia, a type of differentiated tissue macrophage, are considered to be the most plastic cell population of the central nervous system (CNS). In response to pathological conditions, resting microglia undergo a stereotypic activation process and become capable of phagocytosis, antigen presentation, and lymphocyte activation. Considering their immune effector function, it is not surprising to see microglia accumulation in almost every CNS disease process, including malignant brain tumors or malignant gliomas. Although the function of these cells in CNS inflammatory processes is being studied, their role in malignant glioma biology remains unclear. On one hand, microglia may represent a CNS anti-tumor response, which is inactivated by local secretion of immunosuppressive factors by glioma cells. On the other hand, taking into account that microglia are capable of secreting a variety of immunomodulatory cytokines, it is possible that they are attracted by gliomas to promote tumor growth. A better understanding of microglia-glioma interaction will be helpful in designing novel immune-based therapies against these fatal tumors. Copyright 2001 Wiley-Liss, Inc.
Sánchez, Óscar J; Cardona, Carlos A
2012-01-01
In this work, the hierarchical decomposition methodology was used to conceptually design the production of fuel ethanol from sugarcane. The decomposition of the process into six levels of analysis was carried out. Several options of technological configurations were assessed in each level considering economic and environmental criteria. The most promising alternatives were chosen rejecting the ones with a least favorable performance. Aspen Plus was employed for simulation of each one of the technological configurations studied. Aspen Icarus was used for economic evaluation of each configuration, and WAR algorithm was utilized for calculation of the environmental criterion. The results obtained showed that the most suitable synthesized flowsheet involves the continuous cultivation of Zymomonas mobilis with cane juice as substrate and including cell recycling and the ethanol dehydration by molecular sieves. The proposed strategy demonstrated to be a powerful tool for conceptual design of biotechnological processes considering both techno-economic and environmental indicators. Copyright © 2011 Elsevier Ltd. All rights reserved.
[New welding processes and health effects of welding].
La Vecchia, G Marina; Maestrelli, Piero
2011-01-01
This paper describes some of the recent developments in the control technology to enhance capability of Pulse Gas Metal Arc Welding. Friction Stir Welding (FSW) processing has been also considered. FSW is a new solid-state joining technique. Heat generated by friction at the rotating tool softens the material being welded. FSW can be considered a green and energy-efficient technique without deleterious fumes, gas, radiation, and noise. Application of new welding processes is limited and studies on health effects in exposed workers are lacking. Acute and chronic health effects of conventional welding have been described. Metal fume fever and cross-shift decline of lung function are the main acute respiratory effects. Skin and eyes may be affected by heat, electricity and UV radiations. Chronic effects on respiratory system include chronic bronchitis, a benign pneumoconiosis (siderosis), asthma, and a possible increase in the incidence of lung cancer. Pulmonary infections are increased in terms of severity, duration, and frequency among welders.
Importance of considering helium excited states in He+ scattering by an aluminum surface
NASA Astrophysics Data System (ADS)
Iglesias-García, A.; García, Evelina A.; Goldberg, E. C.
2014-11-01
The He+/Al system is a very interesting projectile-surface combination which was thought initially as an example of a pure Auger neutralization mechanism. Then, because of the measured reionization explained by the antibonding interaction of the projectile state with the core target states, the resonant charge exchange with the band states was considered as another important contribution to the neutralization. Nevertheless, by only considering the neutralization to the ground state of helium, the measured ion survival probability is still overestimated. On the other hand, measurements of electron emission from an Al surface bombarded by He positive ions suggested the possibility of occupied excited states of helium due to the ion-surface collision. In this work, we also include the excited states of He within the time-dependent scattering process in which both neutralization mechanisms, resonant and Auger, are simultaneously contemplated. Our starting point is a multiorbital Anderson Hamiltonian projected over the selected space of ground and excited atomic configurations. An extra term related to the Auger mechanism is added to this Hamiltonian. A difference with previous works is that this approach includes the electron spin and, therefore, the spin fluctuation statistics in the charge-exchange process is correctly taken into account. We find a notable improvement in the agreement with the experiments and also that the interference between both mechanisms is not dramatic.
New perspectives for the design of sustainable bioprocesses for phosphorus recovery from waste.
Tarayre, Cédric; De Clercq, Lies; Charlier, Raphaëlle; Michels, Evi; Meers, Erik; Camargo-Valero, Miller; Delvigne, Frank
2016-04-01
Phosphate rock has long been used for the production of phosphorus based chemicals. However, considering the depletion of the reservoirs and the decrease of the quality of phosphate rocks, a potential market is now emerging for the recovery of phosphate from waste and its reuse for different applications. Notably, phosphate recovery from wastewater could be included in a circular economy approach. This review focuses on the use of microbial systems for phosphorus accumulation and recovery, by considering the actual range of analytical techniques available for the monitoring of phosphorus accumulating organisms, as well as the actual biochemical and metabolic engineering toolbox available for the optimization of bioprocesses. In this context, knowledge gathered from process, system and synthetic biology could potentially lead to innovative process design. Copyright © 2016 Elsevier Ltd. All rights reserved.
Applying for ethical approval for research: the main issues.
Gelling, Leslie
2016-01-13
The need to obtain research ethical approval is common to all research involving human participants. This approval must be obtained before research participants can be approached and before data collection can begin. The process of ethical review is one way that research participants can be confident that possible risks have been considered, minimised and deemed acceptable. This article outlines some of the main issues researchers should consider when planning an application for research ethical approval by answering the following six questions: 'Do I need research ethical approval?', 'How many applications will I need to make?', 'Where should I apply for research ethical approval?', 'What do I need to include in my application?', 'What do research ethics committees look for?' and 'What other approvals might I need?' Answering these questions will enable researchers to navigate the ethical review process.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Curtis, Gary P.; Kohler, Matthias; Kannappan, Ramakrishnan
2015-02-24
Scientifically defensible predictions of field scale U(VI) transport in groundwater requires an understanding of key processes at multiple scales. These scales range from smaller than the sediment grain scale (less than 10 μm) to as large as the field scale which can extend over several kilometers. The key processes that need to be considered include both geochemical reactions in solution and at sediment surfaces as well as physical transport processes including advection, dispersion, and pore-scale diffusion. The research summarized in this report includes both experimental and modeling results in batch, column and tracer tests. The objectives of this research weremore » to: (1) quantify the rates of U(VI) desorption from sediments acquired from a uranium contaminated aquifer in batch experiments;(2) quantify rates of U(VI) desorption in column experiments with variable chemical conditions, and(3) quantify nonreactive tracer and U(VI) transport in field tests.« less
Behavior analysis and neuroscience: Complementary disciplines.
Donahoe, John W
2017-05-01
Behavior analysis and neuroscience are disciplines in their own right but are united in that both are subfields of a common overarching field-biology. What most fundamentally unites these disciplines is a shared commitment to selectionism, the Darwinian mode of explanation. In selectionism, the order and complexity observed in nature are seen as the cumulative products of selection processes acting over time on a population of variants-favoring some and disfavoring others-with the affected variants contributing to the population on which future selections operate. In the case of behavior analysis, the central selection process is selection by reinforcement; in neuroscience it is natural selection. The two selection processes are inter-related in that selection by reinforcement is itself the product of natural selection. The present paper illustrates the complementary nature of behavior analysis and neuroscience through considering their joint contributions to three central problem areas: reinforcement-including conditioned reinforcement, stimulus control-including equivalence classes, and memory-including reminding and remembering. © 2017 Society for the Experimental Analysis of Behavior.
NASA Technical Reports Server (NTRS)
Wolf, M.
1979-01-01
To facilitate the task of objectively comparing competing process options, a methodology was needed for the quantitative evaluation of their relative cost effectiveness. Such a methodology was developed and is described, together with three examples for its application. The criterion for the evaluation is the cost of the energy produced by the system. The method permits the evaluation of competing design options for subsystems, based on the differences in cost and efficiency of the subsystems, assuming comparable reliability and service life, or of competing manufacturing process options for such subsystems, which include solar cells or modules. This process option analysis is based on differences in cost, yield, and conversion efficiency contribution of the process steps considered.
Waldau, Susanne; Lindholm, Lars; Wiechel, Anna Helena
2010-08-01
In the Västerbotten County Council in Sweden a priority setting process was undertaken to reallocate existing resources for funding of new methods and activities. Resources were created by limiting low priority services. A procedure for priority setting was constructed and fully tested by engaging the entire organisation. The procedure included priority setting within and between departments and political decision making. Participants' views and experiences were collected as a basis for future improvement of the process. Results indicate that participants appreciated the overall approach and methodology and wished to engage in their improvement. Among the improvement proposals is prolongation of the process in order to improve the knowledge base quality. The procedure for identification of new items for funding also needs to be revised. The priority setting process was considered an overall success because it fulfilled its political goals. Factors considered crucial for success are a wish among managers for an economic strategy that addresses existing internal resource allocation; process management characterized by goal orientation and clear leadership; an elaborate communications strategy integrated early in the process and its management; political unity in support of the procedure, and a strong political commitment throughout the process. Generalizability has already been demonstrated by several health care organisations that performed processes founded on this working model. Copyright 2010 Elsevier Ireland Ltd. All rights reserved.
Review of Options for Ammonia/Ammonium Management
DOE Office of Scientific and Technical Information (OSTI.GOV)
Nash, C. A.
This report is a review of literature supporting practical ammonia/ammonium destruction processes. Melter research supporting Hanford Low Activity Waste (LAW) glass production has shown that significant amounts of ammonia will be in the melter offgas condensate. Further work with secondary waste forms indicates the potential need to remove the ammonia, perhaps by an oxidative process. This review finds likely practical chemical methods to oxidize ammonia in aqueous solution at moderate temperatures and atmospheric pressure, using easily obtained reagents. Leading candidates include nitrite oxidation to produce nitrogen gas, various peroxide oxidative processes, and air stripping. This work reviews many other processesmore » and provides reasoning to not consider those processes further for this application.« less
Mixed Integer Linear Programming model for Crude Palm Oil Supply Chain Planning
NASA Astrophysics Data System (ADS)
Sembiring, Pasukat; Mawengkang, Herman; Sadyadharma, Hendaru; Bu'ulolo, F.; Fajriana
2018-01-01
The production process of crude palm oil (CPO) can be defined as the milling process of raw materials, called fresh fruit bunch (FFB) into end products palm oil. The process usually through a series of steps producing and consuming intermediate products. The CPO milling industry considered in this paper does not have oil palm plantation, therefore the FFB are supplied by several public oil palm plantations. Due to the limited availability of FFB, then it is necessary to choose from which plantations would be appropriate. This paper proposes a mixed integer linear programming model the supply chain integrated problem, which include waste processing. The mathematical programming model is solved using neighborhood search approach.
Review of solar fuel-producing quantum conversion processes
NASA Technical Reports Server (NTRS)
Peterson, D. B.; Biddle, J. R.; Fujita, T.
1984-01-01
The status and potential of fuel-producing solar photochemical processes are discussed. Research focused on splitting water to produce dihydrogen and is at a relatively early stage of development. Current emphasis is primarily directed toward understanding the basic chemistry underlying such quantum conversion processes. Theoretical analyses by various investigators predict a limiting thermodynamic efficiency of 31% for devices with a single photosystem operating with unfocused sunlight at 300 K. When non-idealities are included, it appears unlikely that actual devices will have efficiencies greater than 12 to 15%. Observed efficiencies are well below theoretical limits. Cyclic homogeneous photochemical processes for splitting water have efficiencies considerably less than 1%. Efficiency can be significantly increased by addition of a sacrificial reagent; however, such systems are no longer cyclic and it is doubtful that they would be economical on a commercial scale. The observed efficiencies for photoelectrochemical processes are also low but such systems appear more promising than homogeneous photochemical systems. Operating and systems options, including operation at elevated temperature and hybrid and coupled quantum-thermal conversion processes, are also considered.
Celik, Halil Ibrahim; Elbasan, Bulent; Gucuyener, Kivilcim; Kayihan, Hulya; Huri, Meral
The aim of this study was to analyze the correlation between sensory processing and motor development in preterm infants. We included 30 preterm and 30 term infants with corrected and chronological ages between 10 and 12 mo. We used the Test of Sensory Functions in Infants to evaluate sensory processing and the Alberta Infant Motor Scale to evaluate motor development. The Spearman correlation test indicated a strong positive relationship between sensory processing and motor development in preterm infants (r = .63, p < .001). Given the relationship between sensory processing and motor development in the preterm group, the evaluation of sensory processing and motor development in preterm infants was considered necessary for the effective implementation of physiotherapy assessment and interventions. Copyright © 2018 by the American Occupational Therapy Association, Inc.
Identifying PHM market and network opportunities.
Grube, Mark E; Krishnaswamy, Anand; Poziemski, John; York, Robert W
2015-11-01
Two key processes for healthcare organizations seeking to assume a financially sustainable role in population health management (PHM), after laying the groundwork for the effort, are to identify potential PHM market opportunities and determine the scope of the PHM network. Key variables organizations should consider with respect to market opportunities include the patient population, the overall insurance/employer market, and available types of insurance products. Regarding the network's scope, organizations should consider both traditional strategic criteria for a viable network and at least five additional criteria: network essentiality and PHM care continuum, network adequacy, service distribution right-sizing, network growth strategy, and organizational agility.
Big bang or continuous creation: does life have multiple origins?
NASA Astrophysics Data System (ADS)
Konesky, Gregory A.
2012-10-01
The generally accepted notion of a single origin of life from a primordial soup on the early Earth has been challenged recently by the suggestion of a "second life," "shadow life," and even "biological dark matter." The problem in classifying these microorganisms is in the difficulty or complete failure of the 16s genetic fingerprinting process, suggesting a different underlying biochemistry resulting from at least a second origin of life. We consider an extension of this concept to include continuous origination of life throughout Earth's history, up to the present. The consequences for interpreting the "tree of life" are also considered.
Passos, Isis Pienta Batista Dias; Padoveze, Maria Clara; Roseira, Camila Eugênia; de Figueiredo, Rosely Moralez
2015-01-01
to adapt and validate, by expert consensus, a set of indicators used to assess the sterilization process of dental, medical and hospital supplies to be used in PHC services. qualitative methodological study performed in two stages. The first stage included a focal group composed of experts to adapt the indicators to be used in PHC. In the second stage, the indicators were validated using a 4-point Likert scale, which was completed by judges. A Content Validity Index of ≥ 0.75 was considered to show approval of the indicators. the adaptations implemented by the focal group mainly referred to the physical structure, inclusion of dental care professionals, inclusion of chemical disinfection, and replacement of the hot air and moist heat sterilization methods. The validation stage resulted in an index of 0.96, which ranged from 0.90 to 1.00, for the components of the indicators. the judges considered the indicators after adaptation to be validated. Even though there may be differences among items processed around the world, there certainly are common characteristics, especially in countries with economic and cultural environments similar to Brazil. The inclusion of these indicators to assess the safety of healthcare supplies used in PHC services should be considered.
[Lake eutrophication modeling in considering climatic factors change: a review].
Su, Jie-Qiong; Wang, Xuan; Yang, Zhi-Feng
2012-11-01
Climatic factors are considered as the key factors affecting the trophic status and its process in most lakes. Under the background of global climate change, to incorporate the variations of climatic factors into lake eutrophication models could provide solid technical support for the analysis of the trophic evolution trend of lake and the decision-making of lake environment management. This paper analyzed the effects of climatic factors such as air temperature, precipitation, sunlight, and atmosphere on lake eutrophication, and summarized the research results about the lake eutrophication modeling in considering in considering climatic factors change, including the modeling based on statistical analysis, ecological dynamic analysis, system analysis, and intelligent algorithm. The prospective approaches to improve the accuracy of lake eutrophication modeling with the consideration of climatic factors change were put forward, including 1) to strengthen the analysis of the mechanisms related to the effects of climatic factors change on lake trophic status, 2) to identify the appropriate simulation models to generate several scenarios under proper temporal and spatial scales and resolutions, and 3) to integrate the climatic factors change simulation, hydrodynamic model, ecological simulation, and intelligent algorithm into a general modeling system to achieve an accurate prediction of lake eutrophication under climatic change.
ERIC Educational Resources Information Center
Ward, Robert; Ward, Ronnie
2008-01-01
This study examined the selective attention abilities of a simple, artificial, evolved agent and considered implications of the agent's performance for theories of selective attention and action. The agent processed two targets in continuous time, catching one and then the other. This task required many cognitive operations, including prioritizing…
50 CFR 221.12 - Where and how must documents be filed?
Code of Federal Regulations, 2011 CFR
2011-10-01
... Hearing Process Document Filing and Service § 221.12 Where and how must documents be filed? (a) Place of... facsimile if: (A) The document is 20 pages or less, including all attachments; (B) The sending facsimile..., any document received after 5 p.m. at the place where the filing is due is considered filed on the...
21 CFR 129.80 - Processes and controls.
Code of Federal Regulations, 2013 CFR
2013-04-01
..., including those performed by chemical means or by any other means such as circulation of live steam or hot... intensities shall be considered a minimum: (1) Steam in enclosed system: At least 170 °F for at least 15... be available for official review at reasonable times. [42 FR 14355, Mar. 15, 1977, as amended at 44...
21 CFR 129.80 - Processes and controls.
Code of Federal Regulations, 2014 CFR
2014-04-01
..., including those performed by chemical means or by any other means such as circulation of live steam or hot... intensities shall be considered a minimum: (1) Steam in enclosed system: At least 170 °F for at least 15... be available for official review at reasonable times. [42 FR 14355, Mar. 15, 1977, as amended at 44...
21 CFR 129.80 - Processes and controls.
Code of Federal Regulations, 2012 CFR
2012-04-01
..., including those performed by chemical means or by any other means such as circulation of live steam or hot... intensities shall be considered a minimum: (1) Steam in enclosed system: At least 170 °F for at least 15... be available for official review at reasonable times. [42 FR 14355, Mar. 15, 1977, as amended at 44...
NASA Technical Reports Server (NTRS)
Liou, M. S.; Adamson, T. C., Jr.
1979-01-01
An analysis is presented of the flow in the two inner layers, the Reynolds stress sublayer and the wall layer. Included is the calculation of the shear stress at the wall in the interaction region. The limit processes considered are those used for an inviscid flow.
ERIC Educational Resources Information Center
Michelson, Avra; Rothenberg, Jeff
1993-01-01
The report considers the interaction of trends in information technology and trends in research practices and the policy implications for archives. The information is divided into 4 sections. The first section, an "Overview of Information Technology Trends," discusses end-user computing, which includes ubiquitous computing, end-user…
The Biasing Effects of Unmodeled ARMA Time Series Processes on Latent Growth Curve Model Estimates
ERIC Educational Resources Information Center
Sivo, Stephen; Fan, Xitao; Witta, Lea
2005-01-01
The purpose of this study was to evaluate the robustness of estimated growth curve models when there is stationary autocorrelation among manifest variable errors. The results suggest that when, in practice, growth curve models are fitted to longitudinal data, alternative rival hypotheses to consider would include growth models that also specify…
ERIC Educational Resources Information Center
Choksey, Linda L.
This paper primarily considers the effects of parental and sibling deaths on preadolescent children, including the relationship of child rearing styles to the process of mourning. Through a review of the literature and an integration of several psychological factors, the author shows that familial death places children at risk. However, she…
Time symmetry breaking in Bose-Einstein condensates
NASA Astrophysics Data System (ADS)
Mendonça, J. T.; Gammal, A.
2017-09-01
We consider different processes leading to time symmetry breaking in a Bose-Einstein condensate. Our approach provides a global description of time symmetry breaking, based on the equations of a thermal condensate. This includes quenching and expansion of the condensate, the Kibble-Zurek mechanism associated with the creation of vorticity, the dynamical Casimir effect and the formation of time crystals.
A Study of Students on the Autism Spectrum Transformation in a High School Transition Program
ERIC Educational Resources Information Center
Moore-Gumora, Courteny
2013-01-01
The dissertation explores as ethnography the transformative process of ten student in a program for students with Asperger Syndrome transitioning from high school to college located in an urban high school to include the extracurricular extension referred to as Ethos. The dissertation considers the experience in the context of specialized…
Teacher Candidates' Perception Level of Environmental Pollutant and Their Risk Factors
ERIC Educational Resources Information Center
Oztas, Fulya; Kalipci, Erkan
2009-01-01
It is generally accepted that the environmental education deals with a wide range of environmental experiences, methods and processes. Teaching the subject of the environment should not be considered as an easy task. It should not only cover pure ecology education; but also include the citizenship responsibilities and the problems that are sourced…
ERIC Educational Resources Information Center
Massachusetts Inst. of Tech., Cambridge. Sensory Aids Evaluation and Development Center.
Proceedings from a conference on braille production and services are summarized. Only equipment which is ready for use is considered. Specific methods of producing braille discussed include the following: use of plates from a stereograph, computer line printer, braille embossers or braille writers, continuous strip embossed tape from a teletype…
NASA Technical Reports Server (NTRS)
Norman, Colin
1987-01-01
Detailed mechanisms associated with dynamical process occurring in starburst galaxies are considered including the role of bars, waves, mergers, sinking satellites, self gravitating gas and bulge heating. The current understanding of starburst galaxies both observational and theoretical is placed in the context of theories of galaxy formations, Hubble sequence evolution, starbursts and activity, and the nature of quasar absorption lines.
ERIC Educational Resources Information Center
Douglas, Graeme; McLinden, Mike; Farrell, Ann Marie; Ware, Jean; McCall, Steve; Pavey, Sue
2011-01-01
This article considers the concept of access in the education of visually impaired children and young people, with particular reference to print literacy. The article describes implications for teaching and policy at various levels of the educational process: classroom practice; broader teaching and curriculum requirements (including service…
Code of Federal Regulations, 2011 CFR
2011-04-01
... effective cash management or cost controls resulting in excess cash on hand; (11) Failure to ensure that a... consider the organization's history with regard to the management of other grants, including DOL grants... management system as required by Federal regulations; (4) Willful obstruction of the audit process; (5...
Turney, Kristin; Wildeman, Christopher; Schnittker, Jason
2012-01-01
Dramatic increases in the American imprisonment rate since the mid-1970s have important implications for the life chances of minority men with low educational attainment, including for their health. Although a large literature has considered the collateral consequences of incarceration for a variety of outcomes, studies concerned with health have several limitations: Most focus exclusively on physical health; those concerned with mental health only consider current incarceration or previous incarceration, but never both; some are cross-sectional; many fail to consider mechanisms; and virtually all neglect the role of family processes, thereby overlooking the social roles current and former prisoners inhabit. In this article, we use stress process theory to extend this research by first considering the association between incarceration and major depression and then considering potential mechanisms that explain this association. Results from the Fragile Families and Child Wellbeing Study (N = 3,107) show current and recent incarceration are substantially associated with the risk of major depression, suggesting both immediate and short-term implications. In addition, consistent with stress proliferation theory, the results show the well-known consequences of incarceration for socioeconomic status and family functioning partly explain these associations, suggesting the link between incarceration and depression depends heavily on the consequences of incarceration for economic and social reintegration, not only the direct psychological consequences of confinement.
Optimization of a point-focusing, distributed receiver solar thermal electric system
NASA Technical Reports Server (NTRS)
Pons, R. L.
1979-01-01
This paper presents an approach to optimization of a solar concept which employs solar-to-electric power conversion at the focus of parabolic dish concentrators. The optimization procedure is presented through a series of trade studies, which include the results of optical/thermal analyses and individual subsystem trades. Alternate closed-cycle and open-cycle Brayton engines and organic Rankine engines are considered to show the influence of the optimization process, and various storage techniques are evaluated, including batteries, flywheels, and hybrid-engine operation.
Rare Orbital Infections ~ State of the Art ~ Part II
Hamed-Azzam, Shirin; AlHashash, Islam; Briscoe, Daniel; Rose, Geoffrey E; Verity, David H.
2018-01-01
Infections of the orbit and periorbita are relatively frequent. Identifying unusual organisms is crucial because they can cause severe local and systemic morbidity, despite their rarity. Opportunistic infections of the orbit should be considered mainly in debilitated or immunocompromised patients. The key to successful management includes a high index of suspicion, prompt diagnosis, and addressing the underlying systemic disease. This review summarizes unusual infectious processes of the orbit, including mycobacterial, fungal, and parasitic infections, as well as their pathophysiology, symptoms, signs, and treatment. PMID:29719648
NASA Astrophysics Data System (ADS)
Abdurakhmanov, I. B.; Bailey, J. J.; Kadyrov, A. S.; Bray, I.
2018-03-01
In this work, we develop a wave-packet continuum-discretization approach to ion-atom collisions that includes rearrangement processes. The total scattering wave function is expanded using a two-center basis built from wave-packet pseudostates. The exact three-body Schrödinger equation is converted into coupled-channel differential equations for time-dependent expansion coefficients. In the asymptotic region these time-dependent coefficients represent transition amplitudes for all processes including elastic scattering, excitation, ionization, and electron capture. The wave-packet continuum-discretization approach is ideal for differential ionization studies as it allows one to generate pseudostates with arbitrary energies and distribution. The approach is used to calculate the double differential cross section for ionization in proton collisions with atomic hydrogen. Overall good agreement with experiment is obtained for all considered cases.
Group processes in medical education: learning from social identity theory.
Burford, Bryan
2012-02-01
The clinical workplace in which doctors learn involves many social groups, including representatives of different professions, clinical specialties and workplace teams. This paper suggests that medical education research does not currently take full account of the effects of group membership, and describes a theoretical approach from social psychology, the social identity approach, which allows those effects to be explored. The social identity approach has a long history in social psychology and provides an integrated account of group processes, from the adoption of group identity through a process of self-categorisation, to the biases and conflicts between groups. This paper outlines key elements of this theoretical approach and illustrates their relevance to medical education. The relevance of the social identity approach is illustrated with reference to a number of areas of medical education. The paper shows how research questions in medical education may be usefully reframed in terms of social identity in ways that allow a deeper exploration of the psychological processes involved. Professional identity and professionalism may be viewed in terms of self-categorisation rather than simply attainment; the salience of different identities may be considered as influences on teamwork and interprofessional learning, and issues in communication and assessment may be considered in terms of intergroup biases. Social identity theory provides a powerful framework with which to consider many areas of medical education. It allows disparate influences on, and consequences of, group membership to be considered as part of an integrated system, and allows assumptions, such as about the nature of professional identity and interprofessional tensions, to be made explicit in the design of research studies. This power to question assumptions and develop deeper and more meaningful research questions may be increasingly relevant as the nature and role of the medical profession change. © Blackwell Publishing Ltd 2012.
Equivalence of interest rate models and lattice gases.
Pirjol, Dan
2012-04-01
We consider the class of short rate interest rate models for which the short rate is proportional to the exponential of a Gaussian Markov process x(t) in the terminal measure r(t)=a(t)exp[x(t)]. These models include the Black-Derman-Toy and Black-Karasinski models in the terminal measure. We show that such interest rate models are equivalent to lattice gases with attractive two-body interaction, V(t(1),t(2))=-Cov[x(t(1)),x(t(2))]. We consider in some detail the Black-Karasinski model with x(t) as an Ornstein-Uhlenbeck process, and show that it is similar to a lattice gas model considered by Kac and Helfand, with attractive long-range two-body interactions, V(x,y)=-α(e(-γ|x-y|)-e(-γ(x+y))). An explicit solution for the model is given as a sum over the states of the lattice gas, which is used to show that the model has a phase transition similar to that found previously in the Black-Derman-Toy model in the terminal measure.
Equivalence of interest rate models and lattice gases
NASA Astrophysics Data System (ADS)
Pirjol, Dan
2012-04-01
We consider the class of short rate interest rate models for which the short rate is proportional to the exponential of a Gaussian Markov process x(t) in the terminal measure r(t)=a(t)exp[x(t)]. These models include the Black-Derman-Toy and Black-Karasinski models in the terminal measure. We show that such interest rate models are equivalent to lattice gases with attractive two-body interaction, V(t1,t2)=-Cov[x(t1),x(t2)]. We consider in some detail the Black-Karasinski model with x(t) as an Ornstein-Uhlenbeck process, and show that it is similar to a lattice gas model considered by Kac and Helfand, with attractive long-range two-body interactions, V(x,y)=-α(e-γ|x-y|-e-γ(x+y)). An explicit solution for the model is given as a sum over the states of the lattice gas, which is used to show that the model has a phase transition similar to that found previously in the Black-Derman-Toy model in the terminal measure.
Tooth wear: the view of the anthropologist.
Kaidonis, John A
2008-03-01
Anthropologists have for many years considered human tooth wear a normal physiological phenomenon where teeth, although worn, remain functional throughout life. Wear was considered pathological only if pulpal exposure or premature tooth loss occurred. In addition, adaptive changes to the stomatognathic system in response to wear have been reported including continual eruption, the widening of the masticatory cycle, remodelling of the temporomandibular joint and the shortening of the dental arches from tooth migration. Comparative studies of many different species have also documented these physiological processes supporting the idea of perpetual change over time. In particular, differential wear between enamel and dentine was considered a physiological process relating to the evolution of the form and function of teeth. Although evidence of attrition and abrasion has been known to exist among hunter-gatherer populations for many thousands of years, the prevalence of erosion in such early populations seems insignificant. In particular, non-carious cervical lesions to date have not been observed within these populations and therefore should be viewed as 'modern-day' pathology. Extrapolating this anthropological perspective to the clinical setting has merits, particularly in the prevention of pre-mature unnecessary treatment.
Scott, Finlay; Jardim, Ernesto; Millar, Colin P; Cerviño, Santiago
2016-01-01
Estimating fish stock status is very challenging given the many sources and high levels of uncertainty surrounding the biological processes (e.g. natural variability in the demographic rates), model selection (e.g. choosing growth or stock assessment models) and parameter estimation. Incorporating multiple sources of uncertainty in a stock assessment allows advice to better account for the risks associated with proposed management options, promoting decisions that are more robust to such uncertainty. However, a typical assessment only reports the model fit and variance of estimated parameters, thereby underreporting the overall uncertainty. Additionally, although multiple candidate models may be considered, only one is selected as the 'best' result, effectively rejecting the plausible assumptions behind the other models. We present an applied framework to integrate multiple sources of uncertainty in the stock assessment process. The first step is the generation and conditioning of a suite of stock assessment models that contain different assumptions about the stock and the fishery. The second step is the estimation of parameters, including fitting of the stock assessment models. The final step integrates across all of the results to reconcile the multi-model outcome. The framework is flexible enough to be tailored to particular stocks and fisheries and can draw on information from multiple sources to implement a broad variety of assumptions, making it applicable to stocks with varying levels of data availability The Iberian hake stock in International Council for the Exploration of the Sea (ICES) Divisions VIIIc and IXa is used to demonstrate the framework, starting from length-based stock and indices data. Process and model uncertainty are considered through the growth, natural mortality, fishing mortality, survey catchability and stock-recruitment relationship. Estimation uncertainty is included as part of the fitting process. Simple model averaging is used to integrate across the results and produce a single assessment that considers the multiple sources of uncertainty.
Cleary, Susan; Molyneux, Sassy; English, Mike
2017-01-01
Abstract This paper describes and evaluates the budgeting and planning processes in public hospitals in Kenya. We used a qualitative case study approach to examine these processes in two hospitals in Kenya. We collected data by in-depth interviews of national level policy makers, hospital managers, and frontline practitioners in the case study hospitals (n = 72), a review of documents, and non-participant observations within the hospitals over a 7 month period. We applied an evaluative framework that considers both consequentialist and proceduralist conditions as important to the quality of priority-setting processes. The budgeting and planning process in the case study hospitals was characterized by lack of alignment, inadequate role clarity and the use of informal priority-setting criteria. With regard to consequentialist conditions, the hospitals incorporated economic criteria by considering the affordability of alternatives, but rarely considered the equity of allocative decisions. In the first hospital, stakeholders were aware of - and somewhat satisfied with - the budgeting and planning process, while in the second hospital they were not. Decision making in both hospitals did not result in reallocation of resources. With regard to proceduralist conditions, the budgeting and planning process in the first hospital was more inclusive and transparent, with the stakeholders more empowered compared to the second hospital. In both hospitals, decisions were not based on evidence, implementation of decisions was poor and the community was not included. There were no mechanisms for appeals or to ensure that the proceduralist conditions were met in both hospitals. Public hospitals in Kenya could improve their budgeting and planning processes by harmonizing these processes, improving role clarity, using explicit priority-setting criteria, and by incorporating both consequentialist (efficiency, equity, stakeholder satisfaction and understanding, shifted priorities, implementation of decisions), and proceduralist (stakeholder engagement and empowerment, transparency, use of evidence, revisions, enforcement, and incorporating community values) conditions. PMID:27679522
Barasa, Edwine W; Cleary, Susan; Molyneux, Sassy; English, Mike
2017-04-01
This paper describes and evaluates the budgeting and planning processes in public hospitals in Kenya. We used a qualitative case study approach to examine these processes in two hospitals in Kenya. We collected data by in-depth interviews of national level policy makers, hospital managers, and frontline practitioners in the case study hospitals (n = 72), a review of documents, and non-participant observations within the hospitals over a 7 month period. We applied an evaluative framework that considers both consequentialist and proceduralist conditions as important to the quality of priority-setting processes. The budgeting and planning process in the case study hospitals was characterized by lack of alignment, inadequate role clarity and the use of informal priority-setting criteria. With regard to consequentialist conditions, the hospitals incorporated economic criteria by considering the affordability of alternatives, but rarely considered the equity of allocative decisions. In the first hospital, stakeholders were aware of - and somewhat satisfied with - the budgeting and planning process, while in the second hospital they were not. Decision making in both hospitals did not result in reallocation of resources. With regard to proceduralist conditions, the budgeting and planning process in the first hospital was more inclusive and transparent, with the stakeholders more empowered compared to the second hospital. In both hospitals, decisions were not based on evidence, implementation of decisions was poor and the community was not included. There were no mechanisms for appeals or to ensure that the proceduralist conditions were met in both hospitals. Public hospitals in Kenya could improve their budgeting and planning processes by harmonizing these processes, improving role clarity, using explicit priority-setting criteria, and by incorporating both consequentialist (efficiency, equity, stakeholder satisfaction and understanding, shifted priorities, implementation of decisions), and proceduralist (stakeholder engagement and empowerment, transparency, use of evidence, revisions, enforcement, and incorporating community values) conditions. © The Author 2016. Published by Oxford University Press in association with The London School of Hygiene and Tropical Medicine.
NASA Astrophysics Data System (ADS)
Liberatore, Raffaele; Lanchi, Michela; Turchetti, Luca
2016-05-01
The Hybrid Sulfur (HyS) is a water splitting process for hydrogen production powered with high temperature nuclear heat and electric power; among the numerous thermo-chemical and thermo-electro-chemical cycles proposed in the literature, such cycle is considered to have a particularly high potential also if powered by renewable energy. SOL2HY2 (Solar to Hydrogen Hybrid Cycles) is a 3 year research project, co-funded by the Fuel Cells and Hydrogen Joint Undertaking (FCH JU). A significant part of the project activities are devoted to the analysis and optimization of the integration of the solar power plant with the chemical, hydrogen production plant. This work reports a part of the results obtained in such research activity. The analysis presented in this work builds on previous process simulations used to determine the energy requirements of the hydrogen production plant in terms of electric power, medium (<550°C) and high (>550°C) temperature heat. For the supply of medium temperature (MT) heat, a parabolic trough CSP plant using molten salts as heat transfer and storage medium is considered. A central receiver CSP (Concentrated Solar Power) plant is considered to provide high temperature (HT) heat, which is only needed for sulfuric acid decomposition. Finally, electric power is provided by a power block included in the MT solar plant and/or drawn from the grid, depending on the scenario considered. In particular, the analysis presented here focuses on the medium temperature CSP plant, possibly combined with a power block. Different scenarios were analysed by considering plants with different combinations of geographical location and sizing criteria.
Petersen, Abdul M; Haigh, Kate; Görgens, Johann F
2014-01-01
Flow sheet options for integrating ethanol production from spent sulfite liquor (SSL) into the acid-based sulfite pulping process at the Sappi Saiccor mill (Umkomaas, South Africa) were investigated, including options for generation of thermal and electrical energy from onsite bio-wastes, such as bark. Processes were simulated with Aspen Plus® for mass- and energy-balances, followed by an estimation of the economic viability and environmental impacts. Various concentration levels of the total dissolved solids in magnesium oxide-based SSL, which currently fuels a recovery boiler, prior to fermentation was considered, together with return of the fermentation residues (distillation bottoms) to the recovery boiler after ethanol separation. The generation of renewable thermal and electrical energy from onsite bio-wastes were also included in the energy balance of the combined pulping-ethanol process, in order to partially replace coal consumption. The bio-energy supplementations included the combustion of bark for heat and electricity generation and the bio-digestion of the calcium oxide SSL to produce methane as additional energy source. Ethanol production from SSL at the highest substrate concentration was the most economically feasible when coal was used for process energy. However this solution did not provide any savings in greenhouse gas (GHG) emissions for the concentration-fermentation-distillation process. Maximizing the use of renewable energy sources to partially replace coal consumption yielded a satisfactory economic performance, with a minimum ethanol selling price of 0.83 US$/l , and a drastic reduction in the overall greenhouse gas emissions for the entire facility. High substrate concentrations and conventional distillation should be used when considering integrating ethanol production at sulfite pulping mills. Bio-wastes generated onsite should be utilized at their maximum potential for energy generation in order to maximize the GHG emissions reduction.
Nowak, Marina; Pfaff, Holger; Karbach, Ute
2017-08-24
Quality improvement within health and social care facilities is needed and has to be evidence-based and patient-centered. Value Stream Mapping, a method of Lean management, aims to increase the patients' value and quality of care by a visualization and quantification of the care process. The aim of this research is to examine the effectiveness of Value Stream Mapping on structure, process, and outcome quality in care facilities. A systematic review is conducted. PubMed, EBSCOhost, including Business Source Complete, Academic Search Complete, PSYCInfo, PSYNDX, SocINDEX with Full Text, Web of Knowledge, and EMBASE ScienceDirect are searched in February 2016. All peer-reviewed papers evaluating Value Stream Mapping and published in English or German from January 2000 are included. For data synthesis, all study results are categorized into Donabedian's model of structure, process, and outcome quality. To assess and interpret the effectiveness of Value Stream Mapping, the frequencies of the results statistically examined are considered. Of the 903 articles retrieved, 22 studies fulfill the inclusion criteria. Of these, 11 studies are used to answer the research question. Value Stream Mapping has positive effects on the time dimension of process and outcome quality. It seems to reduce non-value-added time (e.g., waiting time) and length of stay. All study designs are before and after studies without control, and methodologically sophisticated studies are missing. For a final conclusion about Value Stream Mapping's effectiveness, more research with improved methodology is needed. Despite this lack of evidence, Value Stream Mapping has the potential to improve quality of care on the time dimension. The contextual influence has to be investigated to make conclusions about the relationship between different quality domains when applying Value Stream Mapping. However, for using this review's conclusion, the limitation of including heterogeneous and potentially biased results has to be considered.
Developing image processing meta-algorithms with data mining of multiple metrics.
Leung, Kelvin; Cunha, Alexandre; Toga, A W; Parker, D Stott
2014-01-01
People often use multiple metrics in image processing, but here we take a novel approach of mining the values of batteries of metrics on image processing results. We present a case for extending image processing methods to incorporate automated mining of multiple image metric values. Here by a metric we mean any image similarity or distance measure, and in this paper we consider intensity-based and statistical image measures and focus on registration as an image processing problem. We show how it is possible to develop meta-algorithms that evaluate different image processing results with a number of different metrics and mine the results in an automated fashion so as to select the best results. We show that the mining of multiple metrics offers a variety of potential benefits for many image processing problems, including improved robustness and validation.
Parameter optimization of electrochemical machining process using black hole algorithm
NASA Astrophysics Data System (ADS)
Singh, Dinesh; Shukla, Rajkamal
2017-12-01
Advanced machining processes are significant as higher accuracy in machined component is required in the manufacturing industries. Parameter optimization of machining processes gives optimum control to achieve the desired goals. In this paper, electrochemical machining (ECM) process is considered to evaluate the performance of the considered process using black hole algorithm (BHA). BHA considers the fundamental idea of a black hole theory and it has less operating parameters to tune. The two performance parameters, material removal rate (MRR) and overcut (OC) are considered separately to get optimum machining parameter settings using BHA. The variations of process parameters with respect to the performance parameters are reported for better and effective understanding of the considered process using single objective at a time. The results obtained using BHA are found better while compared with results of other metaheuristic algorithms, such as, genetic algorithm (GA), artificial bee colony (ABC) and bio-geography based optimization (BBO) attempted by previous researchers.
Nijp, Jelmer J; Metselaar, Klaas; Limpens, Juul; Teutschbein, Claudia; Peichl, Matthias; Nilsson, Mats B; Berendse, Frank; van der Zee, Sjoerd E A T M
2017-02-15
The water content of the topsoil is one of the key factors controlling biogeochemical processes, greenhouse gas emissions and biosphere - atmosphere interactions in many ecosystems, particularly in northern peatlands. In these wetland ecosystems, the water content of the photosynthetic active peatmoss layer is crucial for ecosystem functioning and carbon sequestration, and is sensitive to future shifts in rainfall and drought characteristics. Current peatland models differ in the degree in which hydrological feedbacks are included, but how this affects peatmoss drought projections is unknown. The aim of this paper was to systematically test whether the level of hydrological detail in models could bias projections of water content and drought stress for peatmoss in northern peatlands using downscaled projections for rainfall and potential evapotranspiration in the current (1991-2020) and future climate (2061-2090). We considered four model variants that either include or exclude moss (rain)water storage and peat volume change, as these are two central processes in the hydrological self-regulation of peatmoss carpets. Model performance was validated using field data of a peatland in northern Sweden. Including moss water storage as well as peat volume change resulted in a significant improvement of model performance, despite the extra parameters added. The best performance was achieved if both processes were included. Including moss water storage and peat volume change consistently reduced projected peatmoss drought frequency with >50%, relative to the model excluding both processes. Projected peatmoss drought frequency in the growing season was 17% smaller under future climate than current climate, but was unaffected by including the hydrological self-regulating processes. Our results suggest that ignoring these two fine-scale processes important in hydrological self-regulation of northern peatlands will have large consequences for projected climate change impact on ecosystem processes related to topsoil water content, such as greenhouse gas emissions. Copyright © 2016 Elsevier B.V. All rights reserved.
Critical thresholds for eventual extinction in randomly disturbed population growth models.
Peckham, Scott D; Waymire, Edward C; De Leenheer, Patrick
2018-02-16
This paper considers several single species growth models featuring a carrying capacity, which are subject to random disturbances that lead to instantaneous population reduction at the disturbance times. This is motivated in part by growing concerns about the impacts of climate change. Our main goal is to understand whether or not the species can persist in the long run. We consider the discrete-time stochastic process obtained by sampling the system immediately after the disturbances, and find various thresholds for several modes of convergence of this discrete process, including thresholds for the absence or existence of a positively supported invariant distribution. These thresholds are given explicitly in terms of the intensity and frequency of the disturbances on the one hand, and the population's growth characteristics on the other. We also perform a similar threshold analysis for the original continuous-time stochastic process, and obtain a formula that allows us to express the invariant distribution for this continuous-time process in terms of the invariant distribution of the discrete-time process, and vice versa. Examples illustrate that these distributions can differ, and this sends a cautionary message to practitioners who wish to parameterize these and related models using field data. Our analysis relies heavily on a particular feature shared by all the deterministic growth models considered here, namely that their solutions exhibit an exponentially weighted averaging property between a function of the initial condition, and the same function applied to the carrying capacity. This property is due to the fact that these systems can be transformed into affine systems.
Commercial application of rainfall simulation
NASA Astrophysics Data System (ADS)
Loch, Rob J.
2010-05-01
Landloch Pty Ltd is a commercial consulting firm, providing advice on a range of land management issues to the mining and construction industries in Australia. As part of the company's day-to-day operations, rainfall simulation is used to assess material erodibility and to investigate a range of site attributes. (Landloch does carry out research projects, though such are not its core business.) When treated as an everyday working tool, several aspects of rainfall simulation practice are distinctively modified. Firstly, the equipment used is regularly maintained, and regularly upgraded with a primary focus on ease, safety, and efficiency of use and on reliability of function. As well, trained and experienced technical support is considered essential. Landloch's chief technician has over 10 years experience in running rainfall simulators at locations across Australia and in Africa and the Pacific. Secondly, the specific experimental conditions established for each set of rainfall simulator runs are carefully considered to ensure that they accurately represent the field conditions to which the data will be subsequently applied. Considerations here include: • wetting and drying cycles to ensure material consolidation and/or cementation if appropriate; • careful attention to water quality if dealing with clay soils or with amendments such as gypsum; • strong focus on ensuring that the erosion processes considered are those of greatest importance to the field situation of concern; and • detailed description of both material and plot properties, to increase the potential for data to be applicable to a wider range of projects and investigations. Other important company procedures include: • For each project, the scientist or engineer responsible for analysing and reporting rainfall simulator data is present during the running of all field plots, as it is essential that they be aware of any specific conditions that may have developed when the plots were subjected to rain; and • Regular calibration of all equipment. In general, typical errors when rainfall simulation is carried out by inexperienced researchers include: • Failure to accurately measure rainfall rates (the most common error); • Inappropriate initial conditions, including wetting treatments; • Use of inappropriately small plots - relating to our concern at the erosion processes considered be those of genuine field relevance; • Inappropriate rainfall kinetic energies; and • Failure to observe critical processes operating on the study plots, such as saturation excess or the presence of impeding layers at shallow depths. Landloch regularly uses erodibility data to design stable batter profiles for minesite waste dumps. Subsequent monitoring of designed dumps has confirmed that modelled erosion rates are consistent with those subsequently measured under field conditions.
Energy-saving management modelling and optimization for lead-acid battery formation process
NASA Astrophysics Data System (ADS)
Wang, T.; Chen, Z.; Xu, J. Y.; Wang, F. Y.; Liu, H. M.
2017-11-01
In this context, a typical lead-acid battery producing process is introduced. Based on the formation process, an efficiency management method is proposed. An optimization model with the objective to minimize the formation electricity cost in a single period is established. This optimization model considers several related constraints, together with two influencing factors including the transformation efficiency of IGBT charge-and-discharge machine and the time-of-use price. An example simulation is shown using PSO algorithm to solve this mathematic model, and the proposed optimization strategy is proved to be effective and learnable for energy-saving and efficiency optimization in battery producing industries.
Thermal analysis of heat and power plant with high temperature reactor and intermediate steam cycle
NASA Astrophysics Data System (ADS)
Fic, Adam; Składzień, Jan; Gabriel, Michał
2015-03-01
Thermal analysis of a heat and power plant with a high temperature gas cooled nuclear reactor is presented. The main aim of the considered system is to supply a technological process with the heat at suitably high temperature level. The considered unit is also used to produce electricity. The high temperature helium cooled nuclear reactor is the primary heat source in the system, which consists of: the reactor cooling cycle, the steam cycle and the gas heat pump cycle. Helium used as a carrier in the first cycle (classic Brayton cycle), which includes the reactor, delivers heat in a steam generator to produce superheated steam with required parameters of the intermediate cycle. The intermediate cycle is provided to transport energy from the reactor installation to the process installation requiring a high temperature heat. The distance between reactor and the process installation is assumed short and negligable, or alternatively equal to 1 km in the analysis. The system is also equipped with a high temperature argon heat pump to obtain the temperature level of a heat carrier required by a high temperature process. Thus, the steam of the intermediate cycle supplies a lower heat exchanger of the heat pump, a process heat exchanger at the medium temperature level and a classical steam turbine system (Rankine cycle). The main purpose of the research was to evaluate the effectiveness of the system considered and to assess whether such a three cycle cogeneration system is reasonable. Multivariant calculations have been carried out employing the developed mathematical model. The results have been presented in a form of the energy efficiency and exergy efficiency of the system as a function of the temperature drop in the high temperature process heat exchanger and the reactor pressure.
Time-dependent crack growth behavior of alloy 617 and alloy 230 at elevated temperatures
NASA Astrophysics Data System (ADS)
Roy, Shawoon Kumar
2011-12-01
Two Ni-base solid-solution-strengthened superalloys: INCONEL 617 and HAYNES 230 were studied to check sustained loading crack growth (SLCG) behavior at elevated temperatures appropriate for Next Generation Nuclear Plant (NGNP) applictaions with constant stress intensity factor (Kmax= 27.75 MPa✓m) in air. The results indicate a time-dependent rate controlling process which can be characterized by a linear elastic fracture mechanics (LEFM) parameter -- stress intensity factor (K). At elevated temperatures, the crack growth mechanism was best described using a damage zone concept. Based on results and study, SAGBOE (stress accelerated grain boundary oxidation embrittlement) is considered the primary reason for time-dependent SLCG. A thermodynamic equation was considered to correlate all the SLCG results to determine the thermal activation energy in the process. A phenomenological model based on a time-dependent factor was developed considering the previous researcher's time-dependent fatigue crack propagation (FCP) results and current SLCG results to relate cycle-dependent and time-dependent FCP for both alloys. Further study includes hold time (3+300s) fatigue testing and no hold (1s) fatigue testing with various load ratios (R) at 700°C with a Kmax of 27.75 MPa✓m. Study results suggest an interesting point: crack growth behavior is significantly affected with the change in R value in cycle-dependent process whereas in time-dependent process, change in R does not have any significant effect. Fractography study showed intergranular cracking mode for all time-dependent processes and transgranular cracking mode for cycle-dependent processes. In Alloy 230, SEM images display intergranular cracking with carbide particles, dense oxides and dimple mixed secondary cracks for time-dependent 3+300s FCP and SLCG test. In all cases, Alloy 230 shows better crack growth resistance compared to Alloy 617.
Space transportation system payload interface verification
NASA Technical Reports Server (NTRS)
Everline, R. T.
1977-01-01
The paper considers STS payload-interface verification requirements and the capability provided by STS to support verification. The intent is to standardize as many interfaces as possible, not only through the design, development, test and evaluation (DDT and E) phase of the major payload carriers but also into the operational phase. The verification process is discussed in terms of its various elements, such as the Space Shuttle DDT and E (including the orbital flight test program) and the major payload carriers DDT and E (including the first flights). Five tools derived from the Space Shuttle DDT and E are available to support the verification process: mathematical (structural and thermal) models, the Shuttle Avionics Integration Laboratory, the Shuttle Manipulator Development Facility, and interface-verification equipment (cargo-integration test equipment).
Severin, Franziska; Borry, Pascal; Cornel, Martina C; Daniels, Norman; Fellmann, Florence; Victoria Hodgson, Shirley; Howard, Heidi C; John, Jürgen; Kääriäinen, Helena; Kayserili, Hülya; Kent, Alastair; Koerber, Florian; Kristoffersson, Ulf; Kroese, Mark; Lewis, Celine; Marckmann, Georg; Meyer, Peter; Pfeufer, Arne; Schmidtke, Jörg; Skirton, Heather; Tranebjærg, Lisbeth; Rogowski, Wolf H
2015-01-01
Given the cost constraints of the European health-care systems, criteria are needed to decide which genetic services to fund from the public budgets, if not all can be covered. To ensure that high-priority services are available equitably within and across the European countries, a shared set of prioritization criteria would be desirable. A decision process following the accountability for reasonableness framework was undertaken, including a multidisciplinary EuroGentest/PPPC-ESHG workshop to develop shared prioritization criteria. Resources are currently too limited to fund all the beneficial genetic testing services available in the next decade. Ethically and economically reflected prioritization criteria are needed. Prioritization should be based on considerations of medical benefit, health need and costs. Medical benefit includes evidence of benefit in terms of clinical benefit, benefit of information for important life decisions, benefit for other people apart from the person tested and the patient-specific likelihood of being affected by the condition tested for. It may be subject to a finite time window. Health need includes the severity of the condition tested for and its progression at the time of testing. Further discussion and better evidence is needed before clearly defined recommendations can be made or a prioritization algorithm proposed. To our knowledge, this is the first time a clinical society has initiated a decision process about health-care prioritization on a European level, following the principles of accountability for reasonableness. We provide points to consider to stimulate this debate across the EU and to serve as a reference for improving patient management. PMID:25248395
Severin, Franziska; Borry, Pascal; Cornel, Martina C; Daniels, Norman; Fellmann, Florence; Victoria Hodgson, Shirley; Howard, Heidi C; John, Jürgen; Kääriäinen, Helena; Kayserili, Hülya; Kent, Alastair; Koerber, Florian; Kristoffersson, Ulf; Kroese, Mark; Lewis, Celine; Marckmann, Georg; Meyer, Peter; Pfeufer, Arne; Schmidtke, Jörg; Skirton, Heather; Tranebjærg, Lisbeth; Rogowski, Wolf H
2015-06-01
Given the cost constraints of the European health-care systems, criteria are needed to decide which genetic services to fund from the public budgets, if not all can be covered. To ensure that high-priority services are available equitably within and across the European countries, a shared set of prioritization criteria would be desirable. A decision process following the accountability for reasonableness framework was undertaken, including a multidisciplinary EuroGentest/PPPC-ESHG workshop to develop shared prioritization criteria. Resources are currently too limited to fund all the beneficial genetic testing services available in the next decade. Ethically and economically reflected prioritization criteria are needed. Prioritization should be based on considerations of medical benefit, health need and costs. Medical benefit includes evidence of benefit in terms of clinical benefit, benefit of information for important life decisions, benefit for other people apart from the person tested and the patient-specific likelihood of being affected by the condition tested for. It may be subject to a finite time window. Health need includes the severity of the condition tested for and its progression at the time of testing. Further discussion and better evidence is needed before clearly defined recommendations can be made or a prioritization algorithm proposed. To our knowledge, this is the first time a clinical society has initiated a decision process about health-care prioritization on a European level, following the principles of accountability for reasonableness. We provide points to consider to stimulate this debate across the EU and to serve as a reference for improving patient management.
Kennedy, Courtney C; Thabane, Lehana; Ioannidis, George; Adachi, Jonathan D; Papaioannou, Alexandra
2014-12-01
To evaluate the feasibility of implementing an interdisciplinary, multifaceted knowledge translation intervention within long-term care (LTC) and to identify any challenges that should be considered in designing future studies. Cluster randomized controlled trial. Forty LTC homes across the province of Ontario, Canada. LTC teams composed of physicians, nurses, pharmacists, and other staff. Cluster-level feasibility measures, including recruitment, retention, data completion, and participation in the intervention. A process evaluation was completed by directors of care indicating which process/policy changes had been implemented. Recruitment and retention rates were 22% and 63%, respectively. Good fidelity with the intervention was achieved, including attendance at educational meetings. After ViDOS, 7 process indicators were being newly implemented by more than 50% of active intervention homes. Despite recruitment and retention challenges, the multifaceted intervention produced a number of policy/process changes and had good intervention fidelity. This study is registered at ClinicalTrials.gov NCT01398527. Copyright © 2014. Published by Elsevier Inc.
Integrating automatic and controlled processes into neurocognitive models of social cognition.
Satpute, Ajay B; Lieberman, Matthew D
2006-03-24
Interest in the neural systems underlying social perception has expanded tremendously over the past few decades. However, gaps between behavioral literatures in social perception and neuroscience are still abundant. In this article, we apply the concept of dual-process models to neural systems in an effort to bridge the gap between many of these behavioral studies and neural systems underlying social perception. We describe and provide support for a neural division between reflexive and reflective systems. Reflexive systems correspond to automatic processes and include the amygdala, basal ganglia, ventromedial prefrontal cortex, dorsal anterior cingulate cortex, and lateral temporal cortex. Reflective systems correspond to controlled processes and include lateral prefrontal cortex, posterior parietal cortex, medial prefrontal cortex, rostral anterior cingulate cortex, and the hippocampus and surrounding medial temporal lobe region. This framework is considered to be a working model rather than a finished product. Finally, the utility of this model and its application to other social cognitive domains such as Theory of Mind are discussed.
In-situ biogas upgrading process: Modeling and simulations aspects.
Lovato, Giovanna; Alvarado-Morales, Merlin; Kovalovszki, Adam; Peprah, Maria; Kougias, Panagiotis G; Rodrigues, José Alberto Domingues; Angelidaki, Irini
2017-12-01
Biogas upgrading processes by in-situ hydrogen (H 2 ) injection are still challenging and could benefit from a mathematical model to predict system performance. Therefore, a previous model on anaerobic digestion was updated and expanded to include the effect of H 2 injection into the liquid phase of a fermenter with the aim of modeling and simulating these processes. This was done by including hydrogenotrophic methanogen kinetics for H 2 consumption and inhibition effect on the acetogenic steps. Special attention was paid to gas to liquid transfer of H 2 . The final model was successfully validated considering a set of Case Studies. Biogas composition and H 2 utilization were correctly predicted, with overall deviation below 10% compared to experimental measurements. Parameter sensitivity analysis revealed that the model is highly sensitive to the H 2 injection rate and mass transfer coefficient. The model developed is an effective tool for predicting process performance in scenarios with biogas upgrading. Copyright © 2017 Elsevier Ltd. All rights reserved.
Epithelialization in Wound Healing: A Comprehensive Review
Pastar, Irena; Stojadinovic, Olivera; Yin, Natalie C.; Ramirez, Horacio; Nusbaum, Aron G.; Sawaya, Andrew; Patel, Shailee B.; Khalid, Laiqua; Isseroff, Rivkah R.; Tomic-Canic, Marjana
2014-01-01
Significance: Keratinocytes, a major cellular component of the epidermis, are responsible for restoring the epidermis after injury through a process termed epithelialization. This review will focus on the pivotal role of keratinocytes in epithelialization, including cellular processes and mechanisms of their regulation during re-epithelialization, and their cross talk with other cell types participating in wound healing. Recent Advances: Discoveries in epidermal stem cells, keratinocyte immune function, and the role of the epidermis as an independent neuroendocrine organ will be reviewed. Novel mechanisms of gene expression regulation important for re-epithelialization, including microRNAs and histone modifications, will also be discussed. Critical Issues: Epithelialization is an essential component of wound healing used as a defining parameter of a successful wound closure. A wound cannot be considered healed in the absence of re-epithelialization. The epithelialization process is impaired in all types of chronic wounds. Future Directions: A comprehensive understanding of the epithelialization process will ultimately lead to the development of novel therapeutic approaches to promote wound closure. PMID:25032064
Processes of ionization of atoms in nonstationary states by the field of an attosecond pulse
NASA Astrophysics Data System (ADS)
Makarov, D. N.; Matveev, V. I.
2015-02-01
Processes of ionization at the interaction of attosecond pulses of an electromagnetic field with atoms in nonstationary states have been considered. The probabilities and ionization cross section at the radiative relaxation of an excited state of a single-electron atom and at the Auger decay of the autoionization state of a two-electron atom have been calculated. The developed method allows the expansion to the case of more complex targets, including those in the collision state, and to various chemical reactions.
Numerical orbit generators of artificial earth satellites
NASA Astrophysics Data System (ADS)
Kugar, H. K.; Dasilva, W. C. C.
1984-04-01
A numerical orbit integrator containing updatings and improvements relative to the previous ones that are being utilized by the Departmento de Mecanica Espacial e Controle (DMC), of INPE, besides incorporating newer modellings resulting from the skill acquired along the time is presented. Flexibility and modularity were taken into account in order to allow future extensions and modifications. Characteristics of numerical accuracy, processing quickness, memory saving as well as utilization aspects were also considered. User's handbook, whole program listing and qualitative analysis of accuracy, processing time and orbit perturbation effects were included as well.
[Effects of migration on the fertility component of urban growth: the case of Tunis].
Picouet, M R
1983-01-01
The relationships among fertility, migration, and urban growth are explored using data from a survey of migration and employment in the city of Tunis, Tunisia. The survey, undertaken in 1972 and 1973, includes data on 1,850 households. Consideration is given to the process of integration of migrant women into urban life and to the consequent changes in their fertility behavior. The problems that these changes in fertility pose for the process of estimating the respective contributions of immigration and fertility to the rate of urban growth are considered.
Workshop on Early Crustal Genesis: Implications from Earth
NASA Technical Reports Server (NTRS)
Phinney, W. C. (Compiler)
1981-01-01
Ways to foster increased study of the early evolution of the Earth, considering the planet as a whole, were explored and recommendations were made to NASA with the intent of exploring optimal ways for integrating Archean studies with problems of planetary evolution. Major themes addressed include: (1) Archean contribution to constraints for modeling planetary evolution; (2) Archean surface conditions and processes as clues to early planetary history; and (3) Archean evidence for physical, chemical and isotopic transfer processes in early planetary crusts. Ten early crustal evolution problems are outlined.
Magnetic transmission gear finite element simulation with iron pole hysteresis
NASA Astrophysics Data System (ADS)
Filippini, Mattia; Alotto, Piergiorgio; Glehn, Gregor; Hameyer, Kay
2018-04-01
Ferromagnetic poles in a magnetic transmission gear require particular attention during their design process. Usually, during the numerical simulation of these devices the effects of hysteresis for loss estimation are neglected and considered only during post-processing calculations. Since the literature lacks hysteresis models, this paper adopts a homogenized hysteretic model able to include eddy current and hysteresis losses in 2D laminated materials for iron poles. In this article the results related to the hysteresis in a magnetic gear are presented and compared to the non-hysteretic approach.
NASA Astrophysics Data System (ADS)
1980-07-01
In most of the processes, a portion of the potassium seed material is converted to a compound not containing sulfur. The potassium in this form can, when injected upstream of the MHD channel, capture the sulfur released during the combustion of coal and eliminate the need for flue gas desulfurization equipment. Criteria considered in the evaluation included cost, state of development, seed loss, power requirements, availability, durability, key component risk, environmental impact, safety, controllability, and impurities buildup.
NASA Astrophysics Data System (ADS)
Sawicki, J.; Siedlaczek, P.; Staszczyk, A.
2018-03-01
A numerical three-dimensional model for computing residual stresses generated in cross section of steel 42CrMo4 after nitriding is presented. The diffusion process is analyzed by the finite-element method. The internal stresses are computed using the obtained profile of the distribution of the nitrogen concentration. The special features of the intricate geometry of the treated articles including edges and angles are considered. Comparative analysis of the results of the simulation and of the experimental measurement of residual stresses is performed by the Waisman-Philips method.
Manufacturing engineering: Principles for optimization
NASA Astrophysics Data System (ADS)
Koenig, Daniel T.
Various subjects in the area of manufacturing engineering are addressed. The topics considered include: manufacturing engineering organization concepts and management techniques, factory capacity and loading techniques, capital equipment programs, machine tool and equipment selection and implementation, producibility engineering, methods, planning and work management, and process control engineering in job shops. Also discussed are: maintenance engineering, numerical control of machine tools, fundamentals of computer-aided design/computer-aided manufacture, computer-aided process planning and data collection, group technology basis for plant layout, environmental control and safety, and the Integrated Productivity Improvement Program.
NASA Astrophysics Data System (ADS)
Moritz, R. E.
2005-12-01
The properties, distribution and temporal variation of sea-ice are reviewed for application to problems of ice-atmosphere chemical processes. Typical vertical structure of sea-ice is presented for different ice types, including young ice, first-year ice and multi-year ice, emphasizing factors relevant to surface chemistry and gas exchange. Time average annual cycles of large scale variables are presented, including ice concentration, ice extent, ice thickness and ice age. Spatial and temporal variability of these large scale quantities is considered on time scales of 1-50 years, emphasizing recent and projected changes in the Arctic pack ice. The amount and time evolution of open water and thin ice are important factors that influence ocean-ice-atmosphere chemical processes. Observations and modeling of the sea-ice thickness distribution function are presented to characterize the range of variability in open water and thin ice.
Quantum and Multidimensional Explanations in a Neurobiological Context of Mind.
Korf, Jakob
2015-08-01
This article examines the possible relevance of physical-mathematical multidimensional or quantum concepts aiming at understanding the (human) mind in a neurobiological context. Some typical features of the quantum and multidimensional concepts are briefly introduced, including entanglement, superposition, holonomic, and quantum field theories. Next, we consider neurobiological principles, such as the brain and its emerging (physical) mind, evolutionary and ontological origins, entropy, syntropy/neg-entropy, causation, and brain energy metabolism. In many biological processes, including biochemical conversions, protein folding, and sensory perception, the ubiquitous involvement of quantum mechanisms is well recognized. Quantum and multidimensional approaches might be expected to help describe and model both brain and mental processes, but an understanding of their direct involvement in mental activity, that is, without mediation by molecular processes, remains elusive. More work has to be done to bridge the gap between current neurobiological and physical-mathematical concepts with their associated quantum-mind theories. © The Author(s) 2014.
NASA Astrophysics Data System (ADS)
Beardsley, Sara; Stochetti, Alejandro; Cerone, Marc
2018-03-01
Akhmat Tower is a 435m supertall building designed by Adrian Smith + Gordon Gill Architecture. It is currently under construction in the city of Grozny, in the Chechen Republic, in the North Caucasus region of Russia. The design of the tower was done during a collaborative process by a multi-disciplinary architectural and engineering team, based primarily in the United States and Russia. During this process, the designers considered many factors including, most primarily, the cultural and historical context, the structural requirements given the high seismicity of the region, and the client's programmatic needs. The resulting crystalline-shaped tower is both an aesthetic statement and a performative architectural solution which will be a new landmark for Chechnya. "The Design of Akhmat Tower" describes in detail the design process including structural considerations, exterior wall design, building program, interior design, the tuned mass damper, and the use of building information modeling.
A Social–Ecological, Process-Oriented Perspective on Political Violence and Child Development
Cummings, E. Mark; Goeke-Morey, Marcie; Merrilees, Christine E.; Taylor, Laura K.; Shirlow, Peter A.
2015-01-01
Youths’ risk for adjustment problems in contexts of political violence is well-documented. However, outcomes vary widely, with many children functioning well. Accordingly, moving beyond further documenting the risk for many negative outcomes associated with living in contexts of political violence, a second generation of research is moving towards identifying the mechanisms and conditions that contribute to children’s adjustment. Increasing support is emerging for understanding effects on children in terms of changes in the social contexts in which children live, and in the psychological processes engaged by these social ecologies. Selected themes are considered, including (a) the need to study multiple levels of the social ecology, (b) differentiating between the effects of exposure to contexts of political versus non-political violence, and (c) theories about explanatory processes. Selected research pertinent to these directions is reviewed, including findings from a six-wave longitudinal study on political violence and children in Northern Ireland. PMID:26877765
Teaching thoughtful practice: narrative pedagogy in addictions education.
Vandermause, Roxanne K; Townsend, Ryan P
2010-07-01
Preparing practitioners for this rapidly changing and demanding health care environment is challenging. A surge in knowledge development and scientific advancement has placed a priority on technical skill and a focus on content driven educational processes that prepare students for evidence-based practice. However, the most difficult health care scenarios require thinking-in-action and thoughtfulness as well as didactic knowledge. It is our contention that interpretive educational methods, like narrative pedagogy, will promote judgment-based practice that includes use of evidence and delivery of thoughtful care. In this article, we describe and interpret a narrative approach to addictions content and teaching thoughtful practice. We present our pedagogical process, including observations and field notes, to show how interpretive pedagogies can be introduced into nursing curricula. By presenting this process, the reader is invited to consider interpretive methods as a way to inspire and habituate thoughtful practice and judgment-based care. Copyright 2009 Elsevier Ltd. All rights reserved.
A Social-Ecological, Process-Oriented Perspective on Political Violence and Child Development.
Cummings, E Mark; Goeke-Morey, Marcie; Merrilees, Christine E; Taylor, Laura K; Shirlow, Peter A
2014-06-01
Youths' risk for adjustment problems in contexts of political violence is well-documented. However, outcomes vary widely, with many children functioning well. Accordingly, moving beyond further documenting the risk for many negative outcomes associated with living in contexts of political violence, a second generation of research is moving towards identifying the mechanisms and conditions that contribute to children's adjustment. Increasing support is emerging for understanding effects on children in terms of changes in the social contexts in which children live, and in the psychological processes engaged by these social ecologies. Selected themes are considered, including (a) the need to study multiple levels of the social ecology, (b) differentiating between the effects of exposure to contexts of political versus non-political violence, and (c) theories about explanatory processes. Selected research pertinent to these directions is reviewed, including findings from a six-wave longitudinal study on political violence and children in Northern Ireland.
TiO2 nanotube platforms for smart drug delivery: a review
Wang, Qun; Huang, Jian-Ying; Li, Hua-Qiong; Chen, Zhong; Zhao, Allan Zi-Jian; Wang, Yi; Zhang, Ke-Qin; Sun, Hong-Tao; Al-Deyab, Salem S; Lai, Yue-Kun
2016-01-01
Titania nanotube (TNT) arrays are recognized as promising materials for localized drug delivery implants because of their excellent properties and facile preparation process. This review highlights the concept of localized drug delivery systems based on TNTs, considering their outstanding biocompatibility in a series of ex vivo and in vivo studies. Considering the safety of TNT implants in the host body, studies of the biocompatibility present significant importance for the clinical application of TNT implants. Toward smart TNT platforms for sustainable drug delivery, several advanced approaches were presented in this review, including controlled release triggered by temperature, light, radiofrequency magnetism, and ultrasonic stimulation. Moreover, TNT implants used in medical therapy have been demonstrated by various examples including dentistry, orthopedic implants, cardiovascular stents, and so on. Finally, a future perspective of TNTs for clinical applications is provided. PMID:27703349
TiO2 nanotube platforms for smart drug delivery: a review.
Wang, Qun; Huang, Jian-Ying; Li, Hua-Qiong; Chen, Zhong; Zhao, Allan Zi-Jian; Wang, Yi; Zhang, Ke-Qin; Sun, Hong-Tao; Al-Deyab, Salem S; Lai, Yue-Kun
Titania nanotube (TNT) arrays are recognized as promising materials for localized drug delivery implants because of their excellent properties and facile preparation process. This review highlights the concept of localized drug delivery systems based on TNTs, considering their outstanding biocompatibility in a series of ex vivo and in vivo studies. Considering the safety of TNT implants in the host body, studies of the biocompatibility present significant importance for the clinical application of TNT implants. Toward smart TNT platforms for sustainable drug delivery, several advanced approaches were presented in this review, including controlled release triggered by temperature, light, radiofrequency magnetism, and ultrasonic stimulation. Moreover, TNT implants used in medical therapy have been demonstrated by various examples including dentistry, orthopedic implants, cardiovascular stents, and so on. Finally, a future perspective of TNTs for clinical applications is provided.
Spacecraft stability and control
NASA Technical Reports Server (NTRS)
Barret, Chris
1992-01-01
The Earth's first artificial satellite, Sputnik 1, slowly tumbled in orbit. The first U.S. satellite, Explorer 1, also tumbled out of control. Today, satellite stability and control has become a higher priority. For a satellite design that is to have a life expectancy of 14 years, appropriate spacecraft flight control systems will be reviewed, stability requirements investigated, and an appropriate flight control system recommended in order to see the design process. Disturbance torques, including aerodynamic, magnetic, gravity gradient, solar, micrometeorite, debris, collision, and internal torques, will be assessed to quantify the disturbance environment so that the required compensating torques can be determined. The control torques, including passive versus active, momentum control, bias momentum, spin stabilization, dual spin, gravity gradient, magnetic, reaction wheels, control moment gyros, inertia augmentation techniques, three-axis control, and reaction control systems (RCSs), will be considered. Conditions for stability will also be considered.
Zhang, Lei; Yue, Hong-Shui; Ju, Ai-Chun; Ye, Zheng-Liang
2016-10-01
Currently, near infrared spectroscopy (NIRS) has been considered as an efficient tool for achieving process analytical technology(PAT) in the manufacture of traditional Chinese medicine (TCM) products. In this article, the NIRS based process analytical system for the production of salvianolic acid for injection was introduced. The design of the process analytical system was described in detail, including the selection of monitored processes and testing mode, and potential risks that should be avoided. Moreover, the development of relative technologies was also presented, which contained the establishment of the monitoring methods for the elution of polyamide resin and macroporous resin chromatography processes, as well as the rapid analysis method for finished products. Based on author's experience of research and work, several issues in the application of NIRS to the process monitoring and control in TCM production were then raised, and some potential solutions were also discussed. The issues include building the technical team for process analytical system, the design of the process analytical system in the manufacture of TCM products, standardization of the NIRS-based analytical methods, and improving the management of process analytical system. Finally, the prospect for the application of NIRS in the TCM industry was put forward. Copyright© by the Chinese Pharmaceutical Association.
Non-hoop winding effect on bonding temperature of laser assisted tape winding process
NASA Astrophysics Data System (ADS)
Zaami, Amin; Baran, Ismet; Akkerman, Remko
2018-05-01
One of the advanced methods for production of thermoplastic composite methods is laser assisted tape winding (LATW). Predicting the temperature in LATW process is very important since the temperature at nip-point (bonding line through width) plays a pivotal role in a proper bonding and hence the mechanical performance. Despite the hoop-winding where the nip-point is the straight line, non-hoop winding includes a curved nip-point line. Hence, the non-hoop winding causes somewhat a different power input through laser-rays and-reflections and consequently generates unknown complex temperature profile on the curved nip-point line. Investigating the temperature at the nip-point line is the point of interest in this study. In order to understand this effect, a numerical model is proposed to capture the effect of laser-rays and their reflections on the nip-point temperature. To this end, a 3D optical model considering the objects in LATW process is considered. Then, the power distribution (absorption and reflection) from the optical analysis is used as an input (heat flux distribution) for the thermal analysis. The thermal analysis employs a fully-implicit advection-diffusion model to calculate the temperature on the surfaces. The results are examined to demonstrate the effect of winding direction on the curved nip-point line (tape width) which has not been considered in literature up to now. Furthermore, the results can be used for designing a better and more efficient setup in the LATW process.
Rugosity and hardness determination in obsidianus lapis for the design of an Yb3+-doped fiber laser
NASA Astrophysics Data System (ADS)
Alvarez-Chavez, J. A.; Aguilar-Morales, A. I.; Perez-Sanchez, G. G.; Morales-Ramirez, A. J.
2015-01-01
Obsidianus lapis is a volcanic rock that has been worked into tools for cutting or weaponry by Teotihuacan people for hundreds of years. Currently, it is used in jewelry or for house decorative items such as elaborated sculptures. From the physico-chemical properties point of view, obsidianus lapis is considered a glass as its composition is 80% silicon dioxide. In México, there are different kinds of obsidianus lapis which are classified according to its colour: rainbow, black, brown, red, silver, golden and snowflake. The traditional grinding process for working with obsidianus lapis includes fixed grinders and sandpaper for the polishing process, where the craftsman grinds the rock manually for obtaining a variety of shapes. Laser processing of natural stones is a relatively new area. We propose the use of an Yb3+-doped fibre laser for cutting and ablating obsidianus lapis into spherical, rectangular and oval shapes. By means of a theoretical analysis of roughness and hardness, which affect the different surfaces and final shapes, and by considering the changes in material temperature during laser interaction, this work will focus on parameter determination such as: laser fluence, incidence angle, laser average power and peak pulse energy, from the proposed Q-switched fibre laser design. Full optical, hardness and rugosity, initial and final characterization will be included in the presentation.
Life of the Earth in the solar atmosphere (multimedia manual)
NASA Astrophysics Data System (ADS)
Kononovich, E. V.; Smirnova, O. B.; Matveychuk, T. V.; Jakunina, G. V.; Krasotkin, S. A.
2006-08-01
The purpose of this manual is to illustrate the major physical processes occurring in the Sun - Earth system and ecology of the planet life. The material includes three individual parts: "The Earth", "The Sun" and "The solar-terrestrial connections". Sections do not require cross-references since each of them is self-complete. Inside the sections the material is located in sequences based on the principle: from simple to complex. The material is designed for students of the senior classes of high school and junior university level interested by the problem. The section "The Earth" is devoted to the description of the basic characteristics of the planet: internal structure, magnetic field, lithosphere and an atmosphere together with various occurring in them tectonic, hydro- and atmospheric processes. The top layers of an atmosphere, an ionosphere, a zone of polar lights, radiating belts, magnetosphere are also considered. The section "The Sun" includes the following subsections: the Sun as a star, internal structure of the Sun, Solar atmosphere, solar activity, cyclicity of the solar activity, helioseismology. In the section "The solar-terrestrial connections" the previous material is used to present the influence of the active solar processes on the most various aspects of a terrestrial life: ecological, biological, mental, social, economic and so forth. The problem of forecasting of the solar activity as the key parameter determining a condition of the so-called space weather is considered.
Radwaste desk reference - Volume 3, Part 2: Liquid waste management. Final report
DOE Office of Scientific and Technical Information (OSTI.GOV)
Deltete, D.; Fisher, S.; Kelly, J.J.
1994-05-01
EPRI began, in late in 1987, to produce a Radwaste Desk Reference that would allow each of the member utilities access to the available information and expertise on radwaste management. EPRI considers this important because radwaste management involves a wide variety of scientific and engineering disciplines. These include chemical and mechanical engineering, chemistry, and health physics. Radwaste management also plays a role in implementing a wide variety of regulatory requirements. These include plant-specific technical specifications, NRC standards for protection against radiation, DOT transportation regulations and major environmental legislation such as the Resource Conservation and Recovery Act. EPRI chose a questionmore » and answer format because it could be easily accessed by radwaste professionals with a variety of interests. The questions were generated at two meetings of utility radwaste professionals and EPRI contractors. Volume 1, which is already in publication, addresses dry active waste generation, processing and measurement. Volume 2 addresses low level waste storage, transportation and disposal. This volume, Volume 3, is being issued in two parts. Part 1 concentrates on the processing of liquid radioactive waste, whereas Part 2, included here, addresses liquid waste management. It includes extensive information and operating practices related to liquid waste generation and control, liquid waste processing systems at existing U.S. nuclear plants, processes for managing wet wastes (handling, dewatering, solidifying, processing, and packaging), and liquid waste measurement and analysis.« less
Life cycle assessment of biomethane use in Argentina.
Morero, Betzabet; Groppelli, Eduardo; Campanella, Enrique A
2015-04-01
Renewable substitutes for natural gas, such as biogas, require adequate treatment to remove impurities. This paper presents the life cycle and environmental impact of upgrading biogas using absorption-desorption process with three different solvents: water, diglycolamine and polyethylene glycol dimethyl ether. The results showed that water produces a minor impact in most of the considered categories, and an economic analysis showed that water is the most feasible solvent for obtaining the lowest payback period. This analysis includes three different sources for biogas production and two end uses for biomethane. The use of different wastes as sources results in different environmental impacts depending on the type of energy used in the anaerobic digestion. The same situation occurs when considering the use of biomethane as a domestic fuel or for power generation. Using energy from biogas to replace conventional energy sources in production and upgrading biogas significantly reduce the environmental impacts of processes. Copyright © 2015 Elsevier Ltd. All rights reserved.
The excavation stage of basin formation - A qualitative model
NASA Technical Reports Server (NTRS)
Croft, S. K.
1981-01-01
One of the most complex problems in planetary geology and geophysics is the determination of the nature of the impact cratering processes at scales of tens to thousands of kilometers that produce the complex morphological structures of multiring basins. The cratering process is frequently considered to be divided into three stages, including a short high-pressure stage of initial contact between the projectile and the planetary crust, a longer excavation or cratering flow stage culminating in the formation of a transient crater, and a still longer modification stage during which the transient crater is modified into the observed final geologic form. The transient crater may be considered as the initial boundary condition of the modification stage. In the present investigation, the nature of the transient crater is indicated by the cratering flow field determined from numerical simulations of the excavation stage. Attention is given to empirical and theoretical scaling.
Robust Crop and Weed Segmentation under Uncontrolled Outdoor Illumination
Jeon, Hong Y.; Tian, Lei F.; Zhu, Heping
2011-01-01
An image processing algorithm for detecting individual weeds was developed and evaluated. Weed detection processes included were normalized excessive green conversion, statistical threshold value estimation, adaptive image segmentation, median filter, morphological feature calculation and Artificial Neural Network (ANN). The developed algorithm was validated for its ability to identify and detect weeds and crop plants under uncontrolled outdoor illuminations. A machine vision implementing field robot captured field images under outdoor illuminations and the image processing algorithm automatically processed them without manual adjustment. The errors of the algorithm, when processing 666 field images, ranged from 2.1 to 2.9%. The ANN correctly detected 72.6% of crop plants from the identified plants, and considered the rest as weeds. However, the ANN identification rates for crop plants were improved up to 95.1% by addressing the error sources in the algorithm. The developed weed detection and image processing algorithm provides a novel method to identify plants against soil background under the uncontrolled outdoor illuminations, and to differentiate weeds from crop plants. Thus, the proposed new machine vision and processing algorithm may be useful for outdoor applications including plant specific direct applications (PSDA). PMID:22163954
Treatment of maladaptive aggression in youth: CERT guidelines II. Treatments and ongoing management.
Scotto Rosato, Nancy; Correll, Christoph U; Pappadopulos, Elizabeth; Chait, Alanna; Crystal, Stephen; Jensen, Peter S
2012-06-01
To develop guidelines for management and treatment of maladaptive aggression in youth in the areas of psychosocial interventions, medication treatments, and side-effect management. Evidence was assembled and evaluated in a multistep process, including systematic reviews of published literature; an expert survey of recommended practices; a consensus conference of researchers, policymakers, clinicians, and family advocates; and review by the steering committee of successive drafts of the recommendations. The Center for Education and Research on Mental Health Therapeutics Treatment of Maladaptive Aggression in Youth guidelines reflect a synthesis of the available evidence, based on this multistep process. This article describes the content, rationale, and evidence for 11 recommendations. Key treatment principles include considering psychosocial interventions, such as evidence-based parent and child skills training as the first line of treatment; targeting the underlying disorder first following evidence-based guidelines; considering individual psychosocial and medical factors, including cardiovascular risk in the selection of agents if medication treatment (ideally with the best evidence base) is initiated; avoiding the use of multiple psychotropic medications simultaneously; and careful monitoring of treatment response, by using structured rating scales, as well as close medical monitoring for side effects, including metabolic changes. Treatment of children with maladaptive aggression is a "moving target" requiring ongoing assimilation of new evidence as it emerges. Based on the existing evidence, the Treatment of Maladaptive Aggression in Youth guidelines provide a framework for management of maladaptive aggression in youth, appropriate for use by primary care clinicians and mental health providers.
Marital Processes, Neuroticism, and Stress as Risk Factors for Internalizing Symptoms
Brock, Rebecca L.; Lawrence, Erika
2013-01-01
Objective Marital discord has a robust association with depression, yet it is rarely considered within broader etiological frameworks of psychopathology. Further, little is known about the particular aspects of relationships that have the greatest impact on psychopathology. The purpose of the present study was to test a novel conceptual framework including neuroticism, specific relationship processes (conflict management, partner support, emotional intimacy, and distribution of power and control), and stress as predictors of internalizing symptoms (depression and anxiety). Method Questionnaire and interview data were collected from 103 husbands and wives 5 times over the first 7 years of marriage. Results Results suggest that neuroticism (an expression of the underlying vulnerability for internalizing disorders) contributes to symptoms primarily through high levels of non-marital stress, an imbalance of power/control in one’s marriage, and poor partner support for husbands, and through greater emotional disengagement for wives. Conclusions Marital processes, neuroticism, and stress work together to significantly predict internalizing symptoms, demonstrating the need to routinely consider dyadic processes in etiological models of individual psychopathology. Specific recommendations for adapting and implementing couple interventions to prevent and treat individual psychopathology are discussed. PMID:24818069
McGuire, Jennifer T.; Smith, Erik W.; Long, David T.; Hyndman, David W.; Haack, Sheridan K.; Klug, Michael J.; Velbel, Michael A.
2000-01-01
A fundamental issue in aquifer biogeochemistry is the means by which solute transport, geochemical processes, and microbiological activity combine to produce spatial and temporal variations in redox zonation. In this paper, we describe the temporal variability of TEAP conditions in shallow groundwater contaminated with both waste fuel and chlorinated solvents. TEAP parameters (including methane, dissolved iron, and dissolved hydrogen) were measured to characterize the contaminant plume over a 3-year period. We observed that concentrations of TEAP parameters changed on different time scales and appear to be related, in part, to recharge events. Changes in all TEAP parameters were observed on short time scales (months), and over a longer 3-year period. The results indicate that (1) interpretations of TEAP conditions in aquifers contaminated with a variety of organic chemicals, such as those with petroleum hydrocarbons and chlorinated solvents, must consider additional hydrogen-consuming reactions (e.g., dehalogenation); (2) interpretations must consider the roles of both in situ (at the sampling point) biogeochemical and solute transport processes; and (3) determinations of microbial communities are often necessary to confirm the interpretations made from geochemical and hydrogeological measurements on these processes.
Romantic Relationships and Criminal Desistance: Pathways and Processes
Wyse, Jessica JB; Harding, David J.; Morenoff, Jeffrey D.
2014-01-01
In dominant theories of criminal desistance, marital relationship formation is understood to be a key “turning point” away from deviant behavior. Empirical studies supporting this claim have largely focused on the positive role of marriage in men's desistance from crime, and relatively few studies have examined the role that non-marital relationships may play in desistance. Drawing on 138 longitudinal in-depth interviews with 22 men and women reentering society from prison, this paper extends the scope of desistance research by additionally considering the significance of more fleeting and fluid relationships, and the diverse processes through which romantic relationships of all sorts are linked with criminal behaviors. We present an empirically-based typology detailing six processes, grouped within three conceptual categories, through which romantic relationships had their effects. These pathways include material circumstances, social bonds and interactions, and emotional supports and stressors. We also consider gender differences in these processes. While more tenuous bonds to marginally conventional partners would seem to exert little effect, as one of the few relationships and social roles available to many former prisoners, we found that they wielded important influence, if not always in a positive direction. PMID:25484489
ERIC Educational Resources Information Center
Stevens, Mary Elizabeth
The series, of which this is the initial report, is intended to give a selective overview of research and development efforts and requirements in the computer and information sciences. The operations of information acquisition, sensing, and input to information processing systems are considered in generalized terms. Specific topics include but are…
Dynamic target ionization using an ultrashort pulse of a laser field
NASA Astrophysics Data System (ADS)
Makarov, D. N.; Matveev, V. I.; Makarova, K. A.
2014-09-01
Ionization processes under the interaction of an ultrashort pulse of an electromagnetic field with atoms in nonstationary states are considered. As an example, the ionization probability of the hydrogen-like atom upon the decay of quasi-stationary state is calculated. The method developed can be applied to complex systems, including targets in collisional states and various chemical reactions.
[Regulatory role of the immune system in the organism].
Alekseev, L P; Khaitov, R M
2010-08-01
The paper presents modern idea of regulatory role of the human immune system in performing a number of physiological functions including intercellular interactions, reproductive process, and forming of protection against external and internal aggression. Significance of the immune system is considered and substantiated, that of genes of the human immune response in particular in provision of human survival as a biological species.
Interoperable Architecture for Command and Control
2014-06-01
defined objective. Elements can include other systems, people, processes, technology and other support elements (Adapted from [9]). Enterprise System...An enterprise is an intentionally created entity of human endeavour with a certain purpose. An enterprise could be considered a type of system [7]. In...this case the enterprise is a Defence Enterprise System required by government as a tool to maintain national sovereignty. Capability