Sample records for product realization process

  1. Concurrency in product realization

    NASA Astrophysics Data System (ADS)

    Kelly, Michael J.

    1994-03-01

    Technology per se does not provide a competitive advantage. Timely exploitation of technology is what gives the competitive edge, and this demands a major shift in the product development process and management of the industrial enterprise. `Teaming to win' is more than a management theme; it is the disciplined engineering practice that is essential to success in today's global marketplace. Teaming supports the concurrent engineering practices required to integrate the activities of people responsible for product realization through achievement of shorter development cycles, lower costs, and defect-free products.

  2. Realization of high quality production schedules: Structuring quality factors via iteration of user specification processes

    NASA Technical Reports Server (NTRS)

    Hamazaki, Takashi

    1992-01-01

    This paper describes an architecture for realizing high quality production schedules. Although quality is one of the most important aspects of production scheduling, it is difficult, even for a user, to specify precisely. However, it is also true that the decision as to whether a scheduler is good or bad can only be made by the user. This paper proposes the following: (1) the quality of a schedule can be represented in the form of quality factors, i.e. constraints and objectives of the domain, and their structure; (2) quality factors and their structure can be used for decision making at local decision points during the scheduling process; and (3) that they can be defined via iteration of user specification processes.

  3. Investigations regarding the evaluation of specific intellectual property production risks within Quality Management System

    NASA Astrophysics Data System (ADS)

    Pakocs, R.; Lupulescu, N. B.

    2016-11-01

    This paper is a theoretical research concerning methods for risk assessment of specific intellectual property production risks that are identified in the product achievement stage within the Quality Management System. In order to realize this, we will start by identifying the specific intellectual property production risks and by proposing some new calculating formulas for minimalizing their negative effects. The theoretical model proposed assessment of specific intellectual property production risks, will be realized based on 3 hypothetical situations. This study intends to reduce the intellectual property risks identified in the production process of commercial societies that have an industrial profile.

  4. Research and exploration of product innovative design for function

    NASA Astrophysics Data System (ADS)

    Wang, Donglin; Wei, Zihui; Wang, Youjiang; Tan, Runhua

    2009-07-01

    Products innovation is under the prerequisite of realizing the new function, the realization of the new function must solve the contradiction. A new process model of new product innovative design was proposed based on Axiomatic Design (AD) Theory and Functional Structure Analysis (FSA), imbedded Principle of Solving Contradiction. In this model, employ AD Theory to guide FSA, determine the contradiction for the realization of the principle solution. To provide powerful support for innovative design tools in principle solution, Principle of Solving Contradiction in the model were imbedded, so as to boost up the innovation of principle solution. As a case study, an innovative design of button battery separator paper punching machine has been achieved with application of the proposed model.

  5. Investigating the Gap Between Estimated and Actual Energy Efficiency and Conservation Savings for Public Buildings Projects & Programs in United States

    NASA Astrophysics Data System (ADS)

    Qaddus, Muhammad Kamil

    The gap between estimated and actual savings in energy efficiency and conservation (EE&C) projects or programs forms the problem statement for the scope of public and government buildings. This gap has been analyzed first on impact and then on process-level. On the impact-level, the methodology leads to categorization of the gap as 'Realization Gap'. It then views the categorization of gap within the context of past and current narratives linked to realization gap. On process-level, the methodology leads to further analysis of realization gap on process evaluation basis. The process evaluation criterion, a product of this basis is then applied to two different programs (DESEU and NYC ACE) linked to the scope of this thesis. Utilizing the synergies of impact and process level analysis, it offers proposals on program development and its structure using our process evaluation criterion. Innovative financing and benefits distribution structure is thus developed and will remain part of the proposal. Restricted Stakeholder Crowd Financing and Risk-Free Incentivized return are the products of proposed financing and benefit distribution structure respectively. These products are then complimented by proposing an alternative approach in estimating EE&C savings. The approach advocates estimation based on range-allocation rather than currently utilized unique estimated savings approach. The Way Ahead section thus explores synergy between financial and engineering ranges of energy savings as a multi-discipline approach for future research. Moreover, it provides the proposed program structure with risk aversion and incentive allocation while dealing with uncertainty. This set of new approaches are believed to better fill the realization gap between estimated and actual energy efficiency savings.

  6. Architecture for distributed design and fabrication

    NASA Astrophysics Data System (ADS)

    McIlrath, Michael B.; Boning, Duane S.; Troxel, Donald E.

    1997-01-01

    We describe a flexible, distributed system architecture capable of supporting collaborative design and fabrication of semi-conductor devices and integrated circuits. Such capabilities are of particular importance in the development of new technologies, where both equipment and expertise are limited. Distributed fabrication enables direct, remote, physical experimentation in the development of leading edge technology, where the necessary manufacturing resources are new, expensive, and scarce. Computational resources, software, processing equipment, and people may all be widely distributed; their effective integration is essential in order to achieve the realization of new technologies for specific product requirements. Our architecture leverages is essential in order to achieve the realization of new technologies for specific product requirements. Our architecture leverages current vendor and consortia developments to define software interfaces and infrastructure based on existing and merging networking, CIM, and CAD standards. Process engineers and product designers access processing and simulation results through a common interface and collaborate across the distributed manufacturing environment.

  7. Impact of the interaction of material production and mechanical processing on the magnetic properties of non-oriented electrical steel

    NASA Astrophysics Data System (ADS)

    Leuning, Nora; Steentjes, Simon; Stöcker, Anett; Kawalla, Rudolf; Wei, Xuefei; Dierdorf, Jens; Hirt, Gerhard; Roggenbuck, Stefan; Korte-Kerzel, Sandra; Weiss, Hannes A.; Volk, Wolfram; Hameyer, Kay

    2018-04-01

    Thin laminations of non-grain oriented (NO) electrical steels form the magnetic core of rotating electrical machines. The magnetic properties of these laminations are therefore key elements for the efficiency of electric drives and need to be fully utilized. Ideally, high magnetization and low losses are realized over the entire polarization and frequency spectrum at reasonable production and processing costs. However, such an ideal material does not exist and thus, achievable magnetic properties need to be deduced from the respective application requirements. Parameters of the electrical steel such as lamination thickness, microstructure and texture affect the magnetic properties as well as their polarization and frequency dependence. These structural features represent possibilities to actively alter the magnetic properties, e.g., magnetization curve, magnetic loss or frequency dependence. This paper studies the influence of production and processing on the resulting magnetic properties of a 2.4 wt% Si electrical steel. Aim is to close the gap between production influence on the material properties and its resulting effect on the magnetization curves and losses at different frequencies with a strong focus on occurring interdependencies between production and mechanical processing. The material production is realized on an experimental processing route that comprises the steps of hot rolling, cold rolling, annealing and punching.

  8. Computer vision challenges and technologies for agile manufacturing

    NASA Astrophysics Data System (ADS)

    Molley, Perry A.

    1996-02-01

    Sandia National Laboratories, a Department of Energy laboratory, is responsible for maintaining the safety, security, reliability, and availability of the nuclear weapons stockpile for the United States. Because of the changing national and global political climates and inevitable budget cuts, Sandia is changing the methods and processes it has traditionally used in the product realization cycle for weapon components. Because of the increasing age of the nuclear stockpile, it is certain that the reliability of these weapons will degrade with time unless eventual action is taken to repair, requalify, or renew them. Furthermore, due to the downsizing of the DOE weapons production sites and loss of technical personnel, the new product realization process is being focused on developing and deploying advanced automation technologies in order to maintain the capability for producing new components. The goal of Sandia's technology development program is to create a product realization environment that is cost effective, has improved quality and reduced cycle time for small lot sizes. The new environment will rely less on the expertise of humans and more on intelligent systems and automation to perform the production processes. The systems will be robust in order to provide maximum flexibility and responsiveness for rapidly changing component or product mixes. An integrated enterprise will allow ready access to and use of information for effective and efficient product and process design. Concurrent engineering methods will allow a speedup of the product realization cycle, reduce costs, and dramatically lessen the dependency on creating and testing physical prototypes. Virtual manufacturing will allow production processes to be designed, integrated, and programed off-line before a piece of hardware ever moves. The overriding goal is to be able to build a large variety of new weapons parts on short notice. Many of these technologies that are being developed are also applicable to commercial production processes and applications. Computer vision will play a critical role in the new agile production environment for automation of processes such as inspection, assembly, welding, material dispensing and other process control tasks. Although there are many academic and commercial solutions that have been developed, none have had widespread adoption considering the huge potential number of applications that could benefit from this technology. The reason for this slow adoption is that the advantages of computer vision for automation can be a double-edged sword. The benefits can be lost if the vision system requires an inordinate amount of time for reprogramming by a skilled operator to account for different parts, changes in lighting conditions, background clutter, changes in optics, etc. Commercially available solutions typically require an operator to manually program the vision system with features used for the recognition. In a recent survey, we asked a number of commercial manufacturers and machine vision companies the question, 'What prevents machine vision systems from being more useful in factories?' The number one (and unanimous) response was that vision systems require too much skill to set up and program to be cost effective.

  9. Manufacturing concepts and development trends in the industrial production of microelectromechanical systems

    NASA Astrophysics Data System (ADS)

    Schuenemann, Matthias; Grimme, Ralf; Kaufmann, Thomas; Schwaab, Gerhard; Baeder, Uwe; Schaefer, Wolfgang; Dorner, Johann

    1998-01-01

    During the past few years, remarkable affords have been made for the realization of microscale sensors, actuators and microelectromechanical system. Due to advances in solid state and micromachining technologies, significant advances in designing, fabricating and testing of microminiaturized devices have been achieved at laboratory level. However, the technical and economical realization of microelectromechanical systems is considerably impeded by the lack of satisfying device technology for their industrial production. A production concept for the industrial production of hybrid microelectromechanical systems was developed and investigated. The concept is based on the resources and requirements of medium-sized enterprises and is characterized by its flexibility. Microsystem fabrication is separated into microfabrication steps performed in-house and technological steps performed by external technology providers. The modularity of the concept allows for a gradual increase in the degree of automation and the in-house production depth, depending on market capacity and financial resources. To demonstrate the feasibility of this approach, the design and realization of a microfabrication process center, which includes tasks like transport and handling, processing, cleaning, testing and storing are discussed. Special attention is given to the supply and feeding of microparts, to the necessary magazines, trays and transport systems, to the implementation of homogeneous mechanical, environmental and information interfaces, to the employment of advanced control, scheduling, and lot tracking concepts, and to the application of highly modular and cost-efficient clean production concepts.

  10. Quality data collection and management technology of aerospace complex product assembly process

    NASA Astrophysics Data System (ADS)

    Weng, Gang; Liu, Jianhua; He, Yongxi; Zhuang, Cunbo

    2017-04-01

    Aiming at solving problems of difficult management and poor traceability for discrete assembly process quality data, a data collection and management method is proposed which take the assembly process and BOM as the core. Data collection method base on workflow technology, data model base on BOM and quality traceability of assembly process is included in the method. Finally, assembly process quality data management system is developed and effective control and management of quality information for complex product assembly process is realized.

  11. Processing multiphoton states through operation on a single photon: Methods and applications

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lin Qing; He Bing; Bergou, Janos A.

    2009-10-15

    Multiphoton states are widely applied in quantum information technology. By the methods presented in this paper, the structure of a multiphoton state in the form of multiple single-photon qubit products can be mapped to a single-photon qudit, which could also be in a separable product with other photons. This makes possible the manipulation of such multiphoton states by processing single-photon states. The optical realization of unknown qubit discrimination [B. He, J. A. Bergou, and Y.-H. Ren, Phys. Rev. A 76, 032301 (2007)] is simplified with the transformation methods. Another application is the construction of quantum logic gates, where the inversemore » transformations back to the input state spaces are also necessary. We especially show that the modified setups to implement the transformations can realize the deterministic multicontrol gates (including Toffoli gate) operating directly on the products of single-photon qubits.« less

  12. Boundaries of the Realizability Region of Membrane Separation Processes

    NASA Astrophysics Data System (ADS)

    Tsirlin, A. M.; Akhrenemkov, A. A.

    2018-01-01

    The region of realizability of membrane separation systems having a constant total membrane area has been determined for a definite output of a final product at a definite composition of a mixture flow. The law of change in the pressure in the mixture, corresponding to the minimum energy required for its separation, was concretized for media close in properties to ideal gases and solutions.

  13. Computerized training for the hardwood sawmill industry: The edging and trimmer trainer (version 3.0)

    Treesearch

    Philip Araman; A Palmer; Matthew Winn; D Kline

    2009-01-01

    In the hardwood sawmill industry, decisions made at the various processing stages directly affect the value of the end product. In order to realize maximum product value, it is essential that employees be properly trained. The edging and trimming stage of lumber processing is one area where lack of proper training can result in poor manufacturing decisions and...

  14. Manipulation and handling processes off-line programming and optimization with use of K-Roset

    NASA Astrophysics Data System (ADS)

    Gołda, G.; Kampa, A.

    2017-08-01

    Contemporary trends in development of efficient, flexible manufacturing systems require practical implementation of modern “Lean production” concepts for maximizing customer value through minimizing all wastes in manufacturing and logistics processes. Every FMS is built on the basis of automated and robotized production cells. Except flexible CNC machine tools and other equipments, the industrial robots are primary elements of the system. In the studies, authors look for wastes of time and cost in real tasks of robots, during manipulation processes. According to aspiration for optimization of handling and manipulation processes with use of the robots, the application of modern off-line programming methods and computer simulation, is the best solution and it is only way to minimize unnecessary movements and other instructions. The modelling process of robotized production cell and offline programming of Kawasaki robots in AS-Language will be described. The simulation of robotized workstation will be realized with use of virtual reality software K-Roset. Authors show the process of industrial robot’s programs improvement and optimization in terms of minimizing the number of useless manipulator movements and unnecessary instructions. This is realized in order to shorten the time of production cycles. This will also reduce costs of handling, manipulations and technological process.

  15. Research and Design on a Product Data Definition System of Semiconductor Packaging Industry

    NASA Astrophysics Data System (ADS)

    Shi, Jinfei; Ma, Qingyao; Zhou, Yifan; Chen, Ruwen

    2017-12-01

    This paper develops a product data definition (PDD) system for a semiconductor packaging and testing company with independent intellectual property rights. The new PDD system can solve the problems such as, the effective control of production plans, the timely feedback of production processes, and the efficient schedule of resources. Firstly, this paper introduces the general requirements of the PDD system and depicts the operation flow and the data flow of the PDD system. Secondly, the overall design scheme of the PDD system is put forward. After that, the physical data model is developed using the Power Designer15.0 tool, and the database system is built. Finally, the function realization and running effects of the PDD system are analysed. The successful operation of the PDD system can realize the information flow among various production departments of the enterprise to meet the standard of the enterprise manufacturing integration and improve the efficiency of production management.

  16. Economic-Oriented Stochastic Optimization in Advanced Process Control of Chemical Processes

    PubMed Central

    Dobos, László; Király, András; Abonyi, János

    2012-01-01

    Finding the optimal operating region of chemical processes is an inevitable step toward improving economic performance. Usually the optimal operating region is situated close to process constraints related to product quality or process safety requirements. Higher profit can be realized only by assuring a relatively low frequency of violation of these constraints. A multilevel stochastic optimization framework is proposed to determine the optimal setpoint values of control loops with respect to predetermined risk levels, uncertainties, and costs of violation of process constraints. The proposed framework is realized as direct search-type optimization of Monte-Carlo simulation of the controlled process. The concept is illustrated throughout by a well-known benchmark problem related to the control of a linear dynamical system and the model predictive control of a more complex nonlinear polymerization process. PMID:23213298

  17. Study on the correlation between volatile fatty acids and gas production in dry fermentation of kitchen waste

    NASA Astrophysics Data System (ADS)

    Li, Qiangqiang; Ma, Yunfeng; Du, Boying; Wang, Qi; Hu, Qiongqiong; Bian, Yushan

    2018-02-01

    In this study, continuous kitchen waste fermentation and anaerobic digestion experiments were conducted to analyze the gas production potential, and to study the correlation between gas production rate and volatile fatty acid (VFAs) and its component concentration. During the experiment, the total solid(TS) concentration of the reaction system was increased by adding the kitchen waste, analysis of kitchen waste dry fermentation process to start, run, imbalance and imbalance after recovery and the parameters in the process of realizing the change trend and influencing factors of dry fermentation process, pH and ammonia concentration.

  18. The research and realization of digital management platform for ultra-precision optical elements within life-cycle

    NASA Astrophysics Data System (ADS)

    Wang, Juan; Wang, Jian; Li, Lijuan; Zhou, Kun

    2014-08-01

    In order to solve the information fusion, process integration, collaborative design and manufacturing for ultra-precision optical elements within life-cycle management, this paper presents a digital management platform which is based on product data and business processes by adopting the modern manufacturing technique, information technique and modern management technique. The architecture and system integration of the digital management platform are discussed in this paper. The digital management platform can realize information sharing and interaction for information-flow, control-flow and value-stream from user's needs to offline in life-cycle, and it can also enhance process control, collaborative research and service ability of ultra-precision optical elements.

  19. Process combinations for the manufacturing of metal-plastic hybrid parts

    NASA Astrophysics Data System (ADS)

    Drossel, W.-G.; Lies, C.; Albert, A.; Haase, R.; Müller, R.; Scholz, P.

    2016-03-01

    The usage of innovative lightweight materials and processing technologies gains importance in manifold industrial scopes. Especially for moving parts and mobility products the weight is decisively. The aerospace and automotive industries use light and high-strength materials to reduce weight and energy consumption and thereby improve the performance of their products. Composites with reinforced plastics are of particular importance. They offer a low density in combination with high specific stiffness and strength. A pure material substitution through reinforced plastics is still not economical. The approach of using hybrid metal-plastic structures with the principle of “using the right material at the right place” is a promising solution for the economical realization of lightweight structures with a high achievement potential. The article shows four innovative manufacturing possibilities for the realization of metal-plastic-hybrid parts.

  20. The Philippine System of Education: Some Implications to Agricultural Education.

    ERIC Educational Resources Information Center

    Mancebo, Samuel T.

    The Philippine educational system views education as a human development resource conversion process that can maximize the realization of the national developmental goals. Students comprise the principal input of this manpower resource conversion process. The output is individuals who can find useful and productive employment. Two broad strategies…

  1. New Soft Magnetic Composites for electromagnetic applications with improved mechanical properties

    NASA Astrophysics Data System (ADS)

    Ferraris, Luca; Pošković, Emir; Franchini, Fausto

    2016-05-01

    The chance to move from 2D to 3D approach in the design of the electrical machines is made possible by the availability of Soft Magnetic Composites (SMC), iron based powders, insulated and pressed to realize shapes otherwise impossible with the traditional lamination sheets technology. Some commercial products are available on the market as "ready to press" powders, which presents good magnetic and energetic properties but are sometimes weak under the mechanical point of view; other products aim at improving this aspect but with considerable process complications and relative cost. The experience of the Authors in the realization of bonded magnets with the adoption of selected organic resins has been partly transferred in the research field of the SMC in order to investigate the possibility to obtain good mechanical properties maintaining the magnetic characteristics of the Insulated Iron Powder Compounds (I.I.P.C.) taken as reference. The paper presents the activity that has been carried out in the realization of SMC mixing iron powders and phenolic resin, in different weight percentages and mold pressures. The obtained results are considered satisfactory under the point of view of the compromise between magnetic and mechanical properties, considering also that the required productive process is simpler. The comparison of the obtained results with those related to commercial products encourages to carry on the research, also because of the reduced cost of the proposed SMC at parity (or better) performance.

  2. HOW TO WRITE A SCIENTIFIC ARTICLE

    PubMed Central

    Manske, Robert C.

    2012-01-01

    Successful production of a written product for submission to a peer‐reviewed scientific journal requires substantial effort. Such an effort can be maximized by following a few simple suggestions when composing/creating the product for submission. By following some suggested guidelines and avoiding common errors, the process can be streamlined and success realized for even beginning/novice authors as they negotiate the publication process. The purpose of this invited commentary is to offer practical suggestions for achieving success when writing and submitting manuscripts to The International Journal of Sports Physical Therapy and other professional journals. PMID:23091783

  3. Production of Magnesium by Vacuum Aluminothermic Reduction with Magnesium Aluminate Spinel as a By-Product

    NASA Astrophysics Data System (ADS)

    Wang, Yaowu; You, Jing; Peng, Jianping; Di, Yuezhong

    2016-06-01

    The Pidgeon process currently accounts for 85% of the world's magnesium production. Although the Pidgeon process has been greatly improved over the past 10 years, such production still consumes much energy and material and creates much pollution. The present study investigates the process of producing magnesium by employing vacuum aluminothermic reduction and by using magnesite as material and obtaining magnesium aluminate spinel as a by-product. The results show that compared with the Pidgeon process, producing magnesium by vacuum aluminothermic reduction can save materials by as much as 50%, increase productivity up to 100%, and save energy by more than 50%. It can also reduce CO2 emission by up to 60% and realize zero discharge of waste residue. Vacuum aluminothermic reduction is a highly efficient, low-energy-consumption, and environmentally friendly method of producing magnesium.

  4. Requirement Assurance: A Verification Process

    NASA Technical Reports Server (NTRS)

    Alexander, Michael G.

    2011-01-01

    Requirement Assurance is an act of requirement verification which assures the stakeholder or customer that a product requirement has produced its "as realized product" and has been verified with conclusive evidence. Product requirement verification answers the question, "did the product meet the stated specification, performance, or design documentation?". In order to ensure the system was built correctly, the practicing system engineer must verify each product requirement using verification methods of inspection, analysis, demonstration, or test. The products of these methods are the "verification artifacts" or "closure artifacts" which are the objective evidence needed to prove the product requirements meet the verification success criteria. Institutional direction is given to the System Engineer in NPR 7123.1A NASA Systems Engineering Processes and Requirements with regards to the requirement verification process. In response, the verification methodology offered in this report meets both the institutional process and requirement verification best practices.

  5. Enzymes and microorganisms in food industry waste processing and conversion to useful products: a review of the literature

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Carroad, P.A.; Wilke, C.R.

    1976-12-01

    Bioconversion of food processing wastes is receiving increased attention with the realization that waste components represent an available and utilizable resource for conversion to useful products. Liquid wastes are characterized as dilute streams containing sugars, starches, proteins, and fats. Solid wastes are generally cellulosic, but may contain other biopolymers. The greatest potential for economic bioconversion is represented by processes to convert cellulose to glucose, glucose to alcohol and protein, starch to invert sugar, and dilute waste streams to methane by anaerobic digestion. Microbial or enzymatic processes to accomplish these conversions are described.

  6. Development Directions for Various Types of the Light Wood-Framed Structures

    NASA Astrophysics Data System (ADS)

    Malesza, J.; Baszeń, M.; Miedziałowski, Cz

    2017-11-01

    The paper presents current trends in the development of the wood-framed structures. Authors describe the evolution of the technology of implementation, the production process of precast elements of buildings as well as selected realization on the site of these kinds of structures. The attention has been paid to the effect of implementation phases on construction and erecting technology of the wood-framed structures. The paper draws attention to the importance and enhancement of structural analysis of structures in individual phases of building realization.

  7. Hydrogen Generation Via Fuel Reforming

    NASA Astrophysics Data System (ADS)

    Krebs, John F.

    2003-07-01

    Reforming is the conversion of a hydrocarbon based fuel to a gas mixture that contains hydrogen. The H2 that is produced by reforming can then be used to produce electricity via fuel cells. The realization of H2-based power generation, via reforming, is facilitated by the existence of the liquid fuel and natural gas distribution infrastructures. Coupling these same infrastructures with more portable reforming technology facilitates the realization of fuel cell powered vehicles. The reformer is the first component in a fuel processor. Contaminants in the H2-enriched product stream, such as carbon monoxide (CO) and hydrogen sulfide (H2S), can significantly degrade the performance of current polymer electrolyte membrane fuel cells (PEMFC's). Removal of such contaminants requires extensive processing of the H2-rich product stream prior to utilization by the fuel cell to generate electricity. The remaining components of the fuel processor remove the contaminants in the H2 product stream. For transportation applications the entire fuel processing system must be as small and lightweight as possible to achieve desirable performance requirements. Current efforts at Argonne National Laboratory are focused on catalyst development and reactor engineering of the autothermal processing train for transportation applications.

  8. Industrial College of the Armed Forces Industry Studies 2002: Biotechnology

    DTIC Science & Technology

    2002-01-01

    The following technologies are commonly included as parts of the biotechnology "industry":3 Fermentation : Early humans realized that the by-products...leavening agent. Yeast also produces alcohol during the production of wine and beer. Bacteria produce lactic acid for making yogurt and acetic acid...for making vinegar. New fermentation processes are being used to produce a wide variety of products including antibiotics, hormones, and enzymes

  9. Novel active driven drop tower facility for microgravity experiments investigating production technologies on the example of substrate-free additive manufacturing

    NASA Astrophysics Data System (ADS)

    Lotz, Christoph; Wessarges, Yvonne; Hermsdorf, Jörg; Ertmer, Wolfgang; Overmeyer, Ludger

    2018-04-01

    Through the striving of humanity into space, new production processes and technologies for the use under microgravity will be essential in the future. Production of objects in space demands for new processes, like additive manufacturing. This paper presents the concept and the realization for a new machine to investigate microgravity production processes on earth. The machine is based on linear long stator drives and a vacuum chamber carrying up to 1000 kg. For the first time high repetition rate and associated low experimental costs can provide basic research. The paper also introduces the substrate-free additive manufacturing as a future research topic and one of our primary application.

  10. Near-infrared spectroscopy monitoring and control of the fluidized bed granulation and coating processes-A review.

    PubMed

    Liu, Ronghua; Li, Lian; Yin, Wenping; Xu, Dongbo; Zang, Hengchang

    2017-09-15

    The fluidized bed granulation and pellets coating technologies are widely used in pharmaceutical industry, because the particles made in a fluidized bed have good flowability, compressibility, and the coating thickness of pellets are homogeneous. With the popularization of process analytical technology (PAT), real-time analysis for critical quality attributes (CQA) was getting more attention. Near-infrared (NIR) spectroscopy, as a PAT tool, could realize the real-time monitoring and control during the granulating and coating processes, which could optimize the manufacturing processes. This article reviewed the application of NIR spectroscopy in CQA (moisture content, particle size and tablet/pellet thickness) monitoring during fluidized bed granulation and coating processes. Through this review, we would like to provide references for realizing automated control and intelligent production in fluidized bed granulation and pellets coating of pharmaceutical industry. Copyright © 2017 Elsevier B.V. All rights reserved.

  11. Genomics to feed a switchgrass breeding program

    USDA-ARS?s Scientific Manuscript database

    Development of improved cultivars is one of three pillars, along with sustainable production and efficient conversion, required for dedicated cellulosic bioenergy crops to succeed. Breeding new cultivars is a long, slow process requiring patience, dedication, and motivation to realize gains and adva...

  12. Microscale technology and biocatalytic processes: opportunities and challenges for synthesis.

    PubMed

    Wohlgemuth, Roland; Plazl, Igor; Žnidaršič-Plazl, Polona; Gernaey, Krist V; Woodley, John M

    2015-05-01

    Despite the expanding presence of microscale technology in chemical synthesis and energy production as well as in biomedical devices and analytical and diagnostic tools, its potential in biocatalytic processes for pharmaceutical and fine chemicals, as well as related industries, has not yet been fully exploited. The aim of this review is to shed light on the strategic advantages of this promising technology for the development and realization of biocatalytic processes and subsequent product recovery steps, demonstrated with examples from the literature. Constraints, opportunities, and the future outlook for the implementation of these key green engineering methods and the role of supporting tools such as mathematical models to establish sustainable production processes are discussed. Copyright © 2015 Elsevier Ltd. All rights reserved.

  13. Advanced optical manufacturing digital integrated system

    NASA Astrophysics Data System (ADS)

    Tao, Yizheng; Li, Xinglan; Li, Wei; Tang, Dingyong

    2012-10-01

    It is necessarily to adapt development of advanced optical manufacturing technology with modern science technology development. To solved these problems which low of ration, ratio of finished product, repetition, consistent in big size and high precision in advanced optical component manufacturing. Applied business driven and method of Rational Unified Process, this paper has researched advanced optical manufacturing process flow, requirement of Advanced Optical Manufacturing integrated System, and put forward architecture and key technology of it. Designed Optical component core and Manufacturing process driven of Advanced Optical Manufacturing Digital Integrated System. the result displayed effective well, realized dynamic planning Manufacturing process, information integration improved ratio of production manufactory.

  14. Modeling Department of Defense controlled atmosphere transshipments for forward deployed forces

    DOT National Transportation Integrated Search

    1998-03-01

    The objective of this thesis is to explore the cost savings, product quality improvement, and process efficiencies that can be realized by the integrated design and application of an innovative logistics system for the purchase and transshipment of f...

  15. [Development of whole process quality control and management system of traditional Chinese medicine decoction pieces based on traditional Chinese medicine quality tree].

    PubMed

    Yu, Wen-Kang; Dong, Ling; Pei, Wen-Xuan; Sun, Zhi-Rong; Dai, Jun-Dong; Wang, Yun

    2017-12-01

    The whole process quality control and management of traditional Chinese medicine (TCM) decoction pieces is a system engineering, involving the base environment, seeds and seedlings, harvesting, processing and other multiple steps, so the accurate identification of factors in TCM production process that may induce the quality risk, as well as reasonable quality control measures are very important. At present, the concept of quality risk is mainly concentrated in the aspects of management and regulations, etc. There is no comprehensive analysis on possible risks in the quality control process of TCM decoction pieces, or analysis summary of effective quality control schemes. A whole process quality control and management system for TCM decoction pieces based on TCM quality tree was proposed in this study. This system effectively combined the process analysis method of TCM quality tree with the quality risk management, and can help managers to make real-time decisions while realizing the whole process quality control of TCM. By providing personalized web interface, this system can realize user-oriented information feedback, and was convenient for users to predict, evaluate and control the quality of TCM. In the application process, the whole process quality control and management system of the TCM decoction pieces can identify the related quality factors such as base environment, cultivation and pieces processing, extend and modify the existing scientific workflow according to their own production conditions, and provide different enterprises with their own quality systems, to achieve the personalized service. As a new quality management model, this paper can provide reference for improving the quality of Chinese medicine production and quality standardization. Copyright© by the Chinese Pharmaceutical Association.

  16. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Elliott, C.

    The Rocky Flats Environmental Technology Site (RFETS) has initiated a major work process improvement campaign using the tools of formalized benchmarking and streamlining. This paper provides insights into some of the process improvement activities performed at Rocky Flats from November 1995 through December 1996. It reviews the background, motivation, methodology, results, and lessons learned from this ongoing effort. The paper also presents important gains realized through process analysis and improvement including significant cost savings, productivity improvements, and an enhanced understanding of site work processes.

  17. Five-Year-olds' Acoustic Realization of Mandarin Tone Sandhi and Lexical Tones in Context Are Not Yet Fully Adult-Like.

    PubMed

    Xu Rattanasone, Nan; Tang, Ping; Yuen, Ivan; Gao, Liqun; Demuth, Katherine

    2018-01-01

    Large numbers of children around the world are learning tone languages, but few studies have examined the acoustic properties of children's early tone productions. Even more scarce are acquisition studies on tone sandhi, a tone change phenomenon which alters the surface realization of lexical tones. Two studies using perceptual coding report the emergence of lexical tone and tone sandhi at around 2 years (Li and Thompson, 1977; Hua and Dodd, 2000). However, the only acoustic study available shows that 3-year-olds are not yet adult-like in their lexical tone productions (Wong, 2012). This raises questions about when children's productions become acoustically adult-like and how their tone productions differ from those of adults. These questions were addressed in the current study which compared Mandarin-speaking pre-schoolers' (3-5-year-olds) tone productions to that of adults. A picture naming task was used with disyllabic real words familiar to pre-schoolers. Overall children produced appropriate tone contours for all tones, i.e., level for tone 1, rising for tones 2, 3 and full sandhi, falling for tone 4 and half sandhi. However, children's productions were not adult-like for tones 3, 4, and the sandhi forms, in terms of coordinating pitch range, slope and curvature , with little evidence of development across ages. These results suggest a protracted process in achieving adult-like acoustic realization of both lexical and sandhi tones.

  18. Quality engineering as a profession.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kolb, Rachel R.; Hoover, Marcey L.

    Over the course of time, the profession of quality engineering has witnessed significant change, from its original emphasis on quality control and inspection to a more contemporary focus on upholding quality processes throughout the organization and its product realization activities. This paper describes the profession of quality engineering, exploring how todays quality engineers and quality professionals are certified individuals committed to upholding quality processes and principles while working with different dimensions of product development. It also discusses the future of the quality engineering profession and the future of the quality movement as a whole.

  19. Investigations of the surface activation of thermoplastic polymers by atmospheric pressure plasma treatment with a stationary plasma jet

    NASA Astrophysics Data System (ADS)

    Moritzer, Elmar; Nordmeyer, Timo; Leister, Christian; Schmidt, Martin Andreas; Grishin, Artur; Knospe, Alexander

    2016-03-01

    The production of high-quality thermoplastic parts often requires an additional process step after the injection molding stage. This may be a coating, bonding process or a 2K-injection moulding process. A commonly used process to improve the bond strength is atmospheric pressure plasma treatment. A variety of applications are realized with the aid of CNC systems. Although they ensure excellent reproducibility, they make it difficult to implement inline applications. This paper therefore examines the possibility of surface treatment using a stationary plasma jet. However, before it is possible to integrate this technology into a production process, preliminary trials need to be carried out to establish which factors influence the process. Experimental tests were performed using a special test set-up, enabling geometric, plasma-specific parameters to be identified. These results can help with the practical integration of this technology into existing production processes.

  20. System simulation of direct-current speed regulation based on Simulink

    NASA Astrophysics Data System (ADS)

    Yang, Meiying

    2018-06-01

    Many production machines require the smooth adjustment of speed in a certain range In the process of modern industrial production, and require good steady-state and dynamic performance. Direct-current speed regulation system with wide speed regulation range, small relative speed variation, good stability, large overload capacity, can bear the frequent impact load, can realize stepless rapid starting-braking and inversion of frequency and other good dynamic performances, can meet the different kinds of special operation requirements in production process of automation system. The direct-current power drive system is almost always used in the field of drive technology of high performance for a long time.

  1. Rough-Surface-Enabled Capacitive Pressure Sensors with 3D Touch Capability.

    PubMed

    Lee, Kilsoo; Lee, Jaehong; Kim, Gwangmook; Kim, Youngjae; Kang, Subin; Cho, Sungjun; Kim, SeulGee; Kim, Jae-Kang; Lee, Wooyoung; Kim, Dae-Eun; Kang, Shinill; Kim, DaeEun; Lee, Taeyoon; Shim, Wooyoung

    2017-11-01

    Fabrication strategies that pursue "simplicity" for the production process and "functionality" for a device, in general, are mutually exclusive. Therefore, strategies that are less expensive, less equipment-intensive, and consequently, more accessible to researchers for the realization of omnipresent electronics are required. Here, this study presents a conceptually different approach that utilizes the inartificial design of the surface roughness of paper to realize a capacitive pressure sensor with high performance compared with sensors produced using costly microfabrication processes. This study utilizes a writing activity with a pencil and paper, which enables the construction of a fundamental capacitor that can be used as a flexible capacitive pressure sensor with high pressure sensitivity and short response time and that it can be inexpensively fabricated over large areas. Furthermore, the paper-based pressure sensors are integrated into a fully functional 3D touch-pad device, which is a step toward the realization of omnipresent electronics. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  2. Advanced Thermoplastic Polymers and Additive Manufacturing Applied to ISS Columbus Toolbox: Lessons Learnt and Results

    NASA Astrophysics Data System (ADS)

    Ferrino, Marinella; Secondo, Ottaviano; Sabbagh, Amir; Della Sala, Emilio

    2014-06-01

    In the frame of the International Space Station (ISS) Exploitation Program a new toolbox has been realized by TAS-I to accommodate the tools currently in use on the ISS Columbus Module utilizing full-scale prototypes obtained with 3D rapid prototyping. The manufacturing of the flight hardware by means of advanced thermoplastic polymer UL TEM 9085 and additive manufacturing Fused Deposition Modelling (FDM) technology represent innovative elements. In this paper, the results achieved and the lessons learned are analyzed to promote future technology know-how. The acquired experience confirmed that the additive manufacturing process allows to save time/cost and to realize new shapes/features to introduce innovation in products and future design processes for space applications.

  3. Concurrent extraction and reaction for the production of biodiesel from wet microalgae.

    PubMed

    Im, Hanjin; Lee, HanSol; Park, Min S; Yang, Ji-Won; Lee, Jae W

    2014-01-01

    This work addresses a reliable in situ transesterification process which integrates lipid extraction from wet microalgae, and its conversion to biodiesel, with a yield higher than 90 wt.%. This process enables single-step production of biodiesel from microalgae by mixing wet microalgal cells with solvent, methanol, and acid catalyst; and then heating them in one pot. The effects of reaction parameters such as reaction temperature, wet cell weight, reaction time, and catalyst volume on the conversion yield are investigated. This simultaneous extraction and transesterification of wet microalgae may enable a significant reduction in energy consumption by eliminating the drying process of algal cells and realize the economic production of biodiesel using wet microalgae. Copyright © 2013 Elsevier Ltd. All rights reserved.

  4. [Discussion on research and development of new traditional Chinese medicine preparation process based on idea of QbD].

    PubMed

    Feng, Yi; Hong, Yan-Long; Xian, Jie-Chen; Du, Ruo-Fei; Zhao, Li-Jie; Shen, Lan

    2014-09-01

    Traditional processes are mostly adopted in traditional Chinese medicine (TCM) preparation production and the quality of products is mostly controlled by terminal. Potential problems of the production in the process are unpredictable and is relied on experience in most cases. Therefore, it is hard to find the key points affecting the preparation process and quality control. A pattern of research and development of traditional Chinese medicine preparation process based on the idea of Quality by Design (QbD) was proposed after introducing the latest research achievement. Basic theories of micromeritics and rheology were used to characterize the physical property of TCM raw material. TCM preparation process was designed in a more scientific and rational way by studying the correlation among enhancing physical property of raw material, preparation process and product quality of preparation. So factors affecting the quality of TCM production would be found out and problems that might occur in the pilot process could be predicted. It would be a foundation for the R&D and production of TCM preparation as well as support for the "process control" of TCMIs gradually realized in the future.

  5. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Schneider, Teresa; Graeff-Honninger, Simone; French, William Todd

    The production of biodiesel has notably increased over the past decade. Currently, plant oil is the main feedstock for biodiesel production, but, due to concerns related to the competition with food production, alternative oil feedstocks have to be found. Oleaginous yeasts are known to produce high amounts of lipids, but no integrated process from microbial fermentation to final biodiesel production has reached commercial realization yet due to economic constraints. Therefore, growth and lipid production of red yeast Rhodotorula glutinis was tested on low-cost substrates, namely, wastewaters from potato, fruit juice, and lettuce processing. Additionally, the production of carotenoids as high-valuemore » by-products was examined. All evaluated wastewaters met the general criteria for microbial lipid production. However, no significant increase in lipid content was observed, probably due to lack of available carbon in wastewaters from fruit juice and lettuce processing, and excess of available nitrogen in potato processing wastewater, respectively. During growth on wastewaters from fruit juice and lettuce processing the carotenoid content increased significantly in the first 48 hours. The relations between carbon content, nitrogen content, and carotenoid production need to be further assessed. For economic viability, lipid and carotenoid production needs to be increased significantly. Lastly, the screening of feedstocks should be extended to other wastewaters.« less

  6. Prelude to rational scale-up of penicillin production: a scale-down study.

    PubMed

    Wang, Guan; Chu, Ju; Noorman, Henk; Xia, Jianye; Tang, Wenjun; Zhuang, Yingping; Zhang, Siliang

    2014-03-01

    Penicillin is one of the best known pharmaceuticals and is also an important member of the β-lactam antibiotics. Over the years, ambitious yields, titers, productivities, and low costs in the production of the β-lactam antibiotics have been stepwise realized through successive rounds of strain improvement and process optimization. Penicillium chrysogenum was proven to be an ideal cell factory for the production of penicillin, and successful approaches were exploited to elevate the production titer. However, the industrial production of penicillin faces the serious challenge that environmental gradients, which are caused by insufficient mixing and mass transfer limitations, exert a considerably negative impact on the ultimate productivity and yield. Scale-down studies regarding diverse environmental gradients have been carried out on bacteria, yeasts, and filamentous fungi as well as animal cells. In accordance, a variety of scale-down devices combined with fast sampling and quenching protocols have been established to acquire the true snapshots of the perturbed cellular conditions. The perturbed metabolome information stemming from scale-down studies contributed to the comprehension of the production process and the identification of improvement approaches. However, little is known about the influence of the flow field and the mechanisms of intracellular metabolism. Consequently, it is still rather difficult to realize a fully rational scale-up. In the future, developing a computer framework to simulate the flow field of the large-scale fermenters is highly recommended. Furthermore, a metabolically structured kinetic model directly related to the production of penicillin will be further coupled to the fluid flow dynamics. A mathematical model including the information from both computational fluid dynamics and chemical reaction dynamics will then be established for the prediction of detailed information over the entire period of the fermentation process and thereby for the optimization of penicillin production, and subsequently also benefiting other fermentation products.

  7. The Road to a Green District

    ERIC Educational Resources Information Center

    Gutter, Rachel; Knupp, Emily

    2011-01-01

    Green design, green construction, and green operations for new buildings are rapidly becoming the norm for school districts throughout the country. Today, increased availability of green products and technology coupled with cost savings that are realized through an integrated design process mean that schools like Arabia Mountain High School in…

  8. The Road to a Green District

    ERIC Educational Resources Information Center

    Gutter, Rachel; Knupp, Emily

    2010-01-01

    Green design, green construction and green operations for new buildings are rapidly becoming the norm for school districts throughout the country. Today, increased availability of green products and technology coupled with cost savings that are realized through an integrated design process mean that schools like Arabia Mountain High School can be…

  9. Development of cost effective fenceline monitoring approaches to support advanced leak detection and repair strategies

    EPA Science Inventory

    Cost-effective fence line and process monitoring systems to support advanced leak detection and repair (LDAR) strategies can enhance protection of public health, facilitate worker safety, and help companies realize cost savings by reducing lost product. The U.S. EPA Office of Re...

  10. An integrated GIS application system for soil moisture data assimilation

    NASA Astrophysics Data System (ADS)

    Wang, Di; Shen, Runping; Huang, Xiaolong; Shi, Chunxiang

    2014-11-01

    The gaps in knowledge and existing challenges in precisely describing the land surface process make it critical to represent the massive soil moisture data visually and mine the data for further research.This article introduces a comprehensive soil moisture assimilation data analysis system, which is instructed by tools of C#, IDL, ArcSDE, Visual Studio 2008 and SQL Server 2005. The system provides integrated service, management of efficient graphics visualization and analysis of land surface data assimilation. The system is not only able to improve the efficiency of data assimilation management, but also comprehensively integrate the data processing and analysis tools into GIS development environment. So analyzing the soil moisture assimilation data and accomplishing GIS spatial analysis can be realized in the same system. This system provides basic GIS map functions, massive data process and soil moisture products analysis etc. Besides,it takes full advantage of a spatial data engine called ArcSDE to effeciently manage, retrieve and store all kinds of data. In the system, characteristics of temporal and spatial pattern of soil moiture will be plotted. By analyzing the soil moisture impact factors, it is possible to acquire the correlation coefficients between soil moisture value and its every single impact factor. Daily and monthly comparative analysis of soil moisture products among observations, simulation results and assimilations can be made in this system to display the different trends of these products. Furthermore, soil moisture map production function is realized for business application.

  11. [Establishment of industry promotion technology system in Chinese medicine secondary exploitation based on "component structure theory"].

    PubMed

    Cheng, Xu-Dong; Feng, Liang; Zhang, Ming-Hua; Gu, Jun-Fei; Jia, Xiao-Bin

    2014-10-01

    The purpose of the secondary exploitation of Chinese medicine is to improve the quality of Chinese medicine products, enhance core competitiveness, for better use in clinical practice, and more effectively solve the patient suffering. Herbs, extraction, separation, refreshing, preparation and quality control are all involved in the industry promotion of Chinese medicine secondary exploitation of industrial production. The Chinese medicine quality improvement and industry promotion could be realized with the whole process of process optimization, quality control, overall processes improvement. Based on the "component structure theory", "multi-dimensional structure & process dynamic quality control system" and systematic and holistic character of Chinese medicine, impacts of whole process were discussed. Technology systems of Chinese medicine industry promotion was built to provide theoretical basis for improving the quality and efficacy of the secondary development of traditional Chinese medicine products.

  12. Potential of Continuous Manufacturing for Liposomal Drug Products.

    PubMed

    Worsham, Robert D; Thomas, Vaughan; Farid, Suzanne S

    2018-05-21

    Over the last several years, continuous manufacturing of pharmaceuticals has evolved from bulk APIs and solid oral dosages into the more complex realm of biologics. The development of continuous downstream processing techniques has allowed biologics manufacturing to realize the benefits (e.g. improved economics, more consistent quality) that come with continuous processing. If relevant processing techniques and principles are selected, the opportunity arises to develop continuous manufacturing designs for additional pharmaceutical products including liposomal drug formulations. Liposome manufacturing has some inherent aspects that make it favorable for a continuous process. Other aspects such as formulation refinement, materials of construction, and aseptic processing need development, but present an achievable challenge. This paper reviews the current state of continuous manufacturing technology applicable to liposomal drug product manufacturing and an assessment of the challenges and potential of this application. This article is protected by copyright. All rights reserved.

  13. Analysis and evaluation of process and equipment in tasks 2 and 4 of the Low Cost Solar Array project

    NASA Technical Reports Server (NTRS)

    Goldman, H.; Wolf, M.

    1978-01-01

    Several experimental and projected Czochralski crystal growing process methods were studied and compared to available operations and cost-data of recent production Cz-pulling, in order to elucidate the role of the dominant cost contributing factors. From this analysis, it becomes apparent that substantial cost reductions can be realized from technical advancements which fall into four categories: an increase in furnace productivity; the reduction of crucible cost through use of the crucible for the equivalent of multiple state-of-the-art crystals; the combined effect of several smaller technical improvements; and a carry over effect of the expected availability of semiconductor grade polysilicon at greatly reduced prices. A format for techno-economic analysis of solar cell production processes was developed, called the University of Pennsylvania Process Characterization (UPPC) format. The accumulated Cz process data are presented.

  14. Limiting factors in the production of deep microstructures

    NASA Astrophysics Data System (ADS)

    Tolfree, David W. L.; O'Neill, William; Tunna, Leslie; Sutcliffe, Christopher

    1999-10-01

    Microsystems increasingly require precision deep microstructures that can be cost-effectively designed and manufactured. New products must be able to meet the demands of the rapidly growing markets for microfluidic, micro- optical and micromechanical devices in industrial sectors which include chemicals, pharmaceuticals, biosciences, medicine and food. The realization of such products, first requires an effective process to design and manufacture prototypes. Two process methods used for the fabrication of high aspect-ratio microstructures are based on X-ray beam lithography with electroforming processes and direct micromachining with a frequency multiplied Nd:YAG laser using nanosecond pulse widths. Factors which limit the efficiency and precision obtainable using such processes are important parameters when deciding on the best fabrication method to use. A basic microstructure with narrow channels suitable for a microfluidic mixer have been fabricated using both these techniques and comparisons made of the limitations and suitability of the processes in respect of fast prototyping and manufacture or working devices.

  15. Electro-optical line cards with multimode polymer waveguides for chip-to-chip interconnects

    NASA Astrophysics Data System (ADS)

    Zhu, Long Xiu; Immonen, Marika; Wu, Jinhua; Yan, Hui Juan; Shi, Ruizhi; Chen, Peifeng; Rapala-Virtanen, Tarja

    2014-10-01

    In this paper, we report developments of electro-optical PCBs (EO-PCB) with low-loss (<0.05dB/cm) polymer waveguides. Our results shows successful fabrication of complex waveguide structures part of hybrid EO-PCBs utilizing production scale process on standard board panels. Test patterns include 90° bends of varying radii (40mm - 2mm), waveguide crossing with varied crossing angles (90°-20°), cascaded bends with varying radii, splitters and tapered waveguides. Full ranges of geometric configurations are required to meet practical optical routing functions and layouts. Moreover, we report results obtained to realize structures to integrate optical connectors with waveguides. Experimental results are shown for MT in-plane and 90° out-of-plane optical connectors realized with coupling loss < 2dB and < 2.5 dB, respectively. These connectors are crucial to realize efficient light coupling from/to TX/RX chip-to-waveguide and within waveguide-to-fiber connections in practical optical PCBs. Furthermore, we show results for fabricating electrical interconnect structures e.g. tracing layers, vias, plated vias top/bottom and through optical layers. Process compatibility with accepted practices and production scale up for high volumes are key concerns to meet the yield target and cost efficiency. Results include waveguide characterization, transmission loss, misalignment tolerance, and effect of lamination. Critical link metrics are reported.

  16. Improving overly manufacturing metrics through application of feedforward mask-bias

    NASA Astrophysics Data System (ADS)

    Joubert, Etienne; Pellegrini, Joseph C.; Misra, Manish; Sturtevant, John L.; Bernhard, John M.; Ong, Phu; Crawshaw, Nathan K.; Puchalski, Vern

    2003-06-01

    Traditional run-to-run controllers that rely on highly correlated historical events to forecast process corrections have been shown to provide substantial benefit over manual control in the case of a fab that is primarily manufacturing high volume, frequent running parts (i.e., DRAM, MPU, and similar operations). However, a limitation of the traditional controller emerges when it is applied to a fab whose work in process (WIP) is composed of primarily short-running, high part count products (typical of foundries and ASIC fabs). This limitation exists because there is a strong likelihood that each reticle has a unique set of process corrections different from other reticles at the same process layer. Further limitations exist when it is realized that each reticle is loaded and aligned differently on multiple exposure tools.A structural change in how the run-to-run controller manages the frequent reticle changes associated with the high part count environment has allowed for breakthrough performance to be achieved. This breakthrough was mad possible by the realization that; 1. Reticle sourced errors were highly stable over long periods of time, thus allowing them to be deconvolved from the day to day tool and process drifts. 2. Reticle sourced errors can be modeled as a feedforward disturbance rather than as discriminates in defining and dividing process streams. In this paper, we show how to deconvolve the static (reticle) and dynamic (day to day tool and process) components from the overall error vector to better forecast feedback for existing products as well as how to compute or learn these values for new product introductions - or new tool startups. Manufacturing data will presented to support this discussion with some real world success stories.

  17. Industrial realization of a direct Fourier transform in automated experimental data processing systems

    NASA Technical Reports Server (NTRS)

    Lyubashevskiy, G. S.

    1973-01-01

    Fourier processing of automatic signals transforms direct current voltage into a numerical form through bandpass filtration in time-pulse multiplying devices. It is shown that the ratio of the interference energy to the useful signal energy is inversely proportional to the square of the product of the depth of the width modulation and the ratio of the time constant averaging to the cross-multiplied signals.

  18. Effects of low-intensity ultrahigh frequency electromagnetic radiation on inflammatory processes.

    PubMed

    Lushnikov, K V; Shumilina, Yu V; Yakushina, V S; Gapeev, A B; Sadovnikov, V B; Chemeris, N K

    2004-04-01

    Low-intensity ultrahigh frequency electromagnetic radiation (42 GHz, 100 microW/cm(2)) reduces the severity of inflammation and inhibits production of active oxygen forms by inflammatory exudate neutrophils only in mice with inflammatory process. These data suggest that some therapeutic effects of electromagnetic radiation can be explained by its antiinflammatory effect which is realized via modulation of functional activity of neutrophils in the focus of inflammation.

  19. A containerless levitation setup for liquid processing in a superconducting magnet.

    PubMed

    Lu, Hui-Meng; Yin, Da-Chuan; Li, Hai-Sheng; Geng, Li-Qiang; Zhang, Chen-Yan; Lu, Qin-Qin; Guo, Yun-Zhu; Guo, Wei-Hong; Shang, Peng; Wakayama, Nobuko I

    2008-09-01

    Containerless processing of materials is considered beneficial for obtaining high quality products due to the elimination of the detrimental effects coming from the contact with container walls. Many containerless processing methods are realized by levitation techniques. This paper describes a containerless levitation setup that utilized the magnetization force generated in a gradient magnetic field. It comprises a levitation unit, a temperature control unit, and a real-time observation unit. Known volume of liquid diamagnetic samples can be levitated in the levitation chamber, the temperature of which is controlled using the temperature control unit. The evolution of the levitated sample is observed in real time using the observation unit. With this setup, containerless processing of liquid such as crystal growth from solution can be realized in a well-controlled manner. Since the levitation is achieved using a superconducting magnet, experiments requiring long duration time such as protein crystallization and simulation of space environment for living system can be easily succeeded.

  20. The role of linguistic experience in the processing of probabilistic information in production.

    PubMed

    Gustafson, Erin; Goldrick, Matthew

    2018-01-01

    Speakers track the probability that a word will occur in a particular context and utilize this information during phonetic processing. For example, content words that have high probability within a discourse tend to be realized with reduced acoustic/articulatory properties. Such probabilistic information may influence L1 and L2 speech processing in distinct ways (reflecting differences in linguistic experience across groups and the overall difficulty of L2 speech processing). To examine this issue, L1 and L2 speakers performed a referential communication task, describing sequences of simple actions. The two groups of speakers showed similar effects of discourse-dependent probabilistic information on production, suggesting that L2 speakers can successfully track discourse-dependent probabilities and use such information to modulate phonetic processing.

  1. Hydrogenation of silyl formates: sustainable production of silanol and methanol from hydrosilane and carbon dioxide.

    PubMed

    Koo, Jangwoo; Kim, Seung Hyo; Hong, Soon Hyeok

    2018-05-10

    A new process for simultaneously obtaining two chemical building blocks, methanol and silanol, was realized starting from silyl formates which can be derived from silane and carbon dioxide. Understanding the reaction mechanism enabled us to improve the reaction efficiency by the addition of a small amount of methanol.

  2. Building an efficient supply chain.

    PubMed

    Scalise, Dagmara

    2005-08-01

    Realizing at last that supply chain management can produce efficiencies and save costs, hospitals are beginning to adopt practices from other industries, such as the concept of extended supply chains, to improve product flow. They're also investing in enterprise planning resource software, radio frequency identification and other technologies, using quality data to drive standardization and streamlining processes.

  3. Increasing Awareness of Practice through Interaction across Communities: The Lived Experiences of a Mathematician and Mathematics Teacher Educator

    ERIC Educational Resources Information Center

    Bleiler, Sarah K.

    2015-01-01

    Collaborations between mathematicians and mathematics teacher educators are increasingly being expected, and realized, within the context of mathematics teacher education. Most research related to collaborative efforts between members of the mathematics and mathematics education communities has focused on the products, rather than the process of…

  4. Deep anisotropic ICP plasma etching designed for high-volume MEMS manufacturing

    NASA Astrophysics Data System (ADS)

    Yu, Keven; Feldbaum, Michael; Pandhumsoporn, Tam; Gadgil, Prashant

    1999-08-01

    ICP plasma etching is gaining widespread acceptance as an enabling micromachining technology for advanced MEMS fabrication. Whereas this technology has shown a capability of delivering multiple novel applications for R and D, its acceptance by industry for high volume production has been limited. This acceptance into production will only occur when the plasma etching equipment with this technology offers the device performance, throughput, reliability, and uptime criteria required by a production facility. The design of the plasma etcher using this technology and the process capability it consequently delivers, has significant implications in making this a reality. Alcatel has been supplying such a technology to this MEMS industry for over 5 years and in the interim has evolved its product and process to make this technology production worthy. Alcatel's next generation etcher, the Alcatel 601E, offers multiple advantages to MEMS manufacturers in realizing their production goals.

  5. Multitriangulations, pseudotriangulations and some problems of realization of polytopes

    NASA Astrophysics Data System (ADS)

    Pilaud, Vincent

    2010-09-01

    This thesis explores two specific topics of discrete geometry, the multitriangulations and the polytopal realizations of products, whose connection is the problem of finding polytopal realizations of a given combinatorial structure. A k-triangulation is a maximal set of chords of the convex n-gon such that no k+1 of them mutually cross. We propose a combinatorial and geometric study of multitriangulations based on their stars, which play the same role as triangles of triangulations. This study leads to interpret multitriangulations by duality as pseudoline arrangements with contact points covering a given support. We exploit finally these results to discuss some open problems on multitriangulations, in particular the question of the polytopal realization of their flip graphs. We study secondly the polytopality of Cartesian products. We investigate the existence of polytopal realizations of cartesian products of graphs, and we study the minimal dimension that can have a polytope whose k-skeleton is that of a product of simplices.

  6. Production Process of Biocompatible Magnesium Alloy Tubes Using Extrusion and Dieless Drawing Processes

    NASA Astrophysics Data System (ADS)

    Kustra, Piotr; Milenin, Andrij; Płonka, Bartłomiej; Furushima, Tsuyoshi

    2016-06-01

    Development of technological production process of biocompatible magnesium tubes for medical applications is the subject of the present paper. The technology consists of two stages—extrusion and dieless drawing process, respectively. Mg alloys for medical applications such as MgCa0.8 are characterized by low technological plasticity during deformation that is why optimization of production parameters is necessary to obtain good quality product. Thus, authors developed yield stress and ductility model for the investigated Mg alloy and then used the numerical simulations to evaluate proper manufacturing conditions. Grid Extrusion3d software developed by authors was used to determine optimum process parameters for extrusion—billet temperature 400 °C and extrusion velocity 1 mm/s. Based on those parameters the tube with external diameter 5 mm without defects was manufactured. Then, commercial Abaqus software was used for modeling dieless drawing. It was shown that the reduction in the area of 60% can be realized for MgCa0.8 magnesium alloy. Tubes with the final diameter of 3 mm were selected as a case study, to present capabilities of proposed processes.

  7. Beyond Solar Fuels: Renewable Energy-Driven Chemistry.

    PubMed

    Lanzafame, Paola; Abate, Salvatare; Ampelli, Claudio; Genovese, Chiara; Passalacqua, Rosalba; Centi, Gabriele; Perathoner, Siglinda

    2017-11-23

    The future feasibility of decarbonized industrial chemical production based on the substitution of fossil feedstocks (FFs) with renewable energy (RE) sources is discussed. Indeed, the use of FFs as an energy source has the greatest impact on the greenhouse gas emissions of chemical production. This future scenario is indicated as "solar-driven" or "RE-driven" chemistry. Its possible implementation requires to go beyond the concept of solar fuels, in particular to address two key aspects: i) the use of RE-driven processes for the production of base raw materials, such as olefins, methanol, and ammonia, and ii) the development of novel RE-driven routes that simultaneously realize process and energy intensification, particularly in the direction of a significant reduction of the number of the process steps. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  8. Screening of industrial wastewaters as feedstock for the microbial production of oils for biodiesel production and high-quality pigments

    DOE PAGES

    Schneider, Teresa; Graeff-Honninger, Simone; French, William Todd; ...

    2012-01-01

    The production of biodiesel has notably increased over the past decade. Currently, plant oil is the main feedstock for biodiesel production, but, due to concerns related to the competition with food production, alternative oil feedstocks have to be found. Oleaginous yeasts are known to produce high amounts of lipids, but no integrated process from microbial fermentation to final biodiesel production has reached commercial realization yet due to economic constraints. Therefore, growth and lipid production of red yeast Rhodotorula glutinis was tested on low-cost substrates, namely, wastewaters from potato, fruit juice, and lettuce processing. Additionally, the production of carotenoids as high-valuemore » by-products was examined. All evaluated wastewaters met the general criteria for microbial lipid production. However, no significant increase in lipid content was observed, probably due to lack of available carbon in wastewaters from fruit juice and lettuce processing, and excess of available nitrogen in potato processing wastewater, respectively. During growth on wastewaters from fruit juice and lettuce processing the carotenoid content increased significantly in the first 48 hours. The relations between carbon content, nitrogen content, and carotenoid production need to be further assessed. For economic viability, lipid and carotenoid production needs to be increased significantly. Lastly, the screening of feedstocks should be extended to other wastewaters.« less

  9. Resource Efficient Metal and Material Recycling

    NASA Astrophysics Data System (ADS)

    Reuter, Markus A.; van Schaik, Antoinette

    Metals enable sustainability through their use and their recyclability. However, various factors can affect the Resource Efficiency of Metal Processing and Recycling. Some typical factors that enable Resource Efficiency include and arranged under the drivers of sustainability: Environment (Maximize Resource Efficiency — Energy, Recyclates, Materials, Water, Sludges, Emissions, Land); Economic Feasibility (BAT & Recycling Systems Simulation / Digitalization, Product vis-à-vis Material Centric Recycling); and Social — Licence to Operate (Legislation, consumer, policy, theft, manual labour.). In order to realize this primary production has to be linked systemically with typical actors in the recycling chain such as Original Equipment Manufacturers (OEMs), Recyclers & Collection, Physical separation specialists as well as process metallurgical operations that produce high value metals, compounds and products that recycle back to products. This is best done with deep knowledge of multi-physics, technology, product & system design, process control, market, life cycle management, policy, to name a few. The combination of these will be discussed as Design for Sustainability (DfS) and Design for Recycling (DfR) applications.

  10. Reduction of CO2 to C1 products and fuel

    USGS Publications Warehouse

    Mill, T.; Ross, D.

    2002-01-01

    Photochemical semiconductor processes readily reduced CO2 to a broad range of C1 products. However the intrinsic and solar efficiencies for the processes were low. Improved quantum efficiencies could be realized utilizing quantum-sized particles, but at the expense of using less of the visible solar spectrum. Conversely, semiconductors with small bandgaps used more of the visible solar spectrum at the expense of quantum efficiency. Thermal reduction of CO2 with Fe(II) was thermodynamically favored for forming many kinds of organic compounds and occurred readily with olivine and other Fe(II) minerals above 200??C to form higher alkanes and alkenes. No added hydrogen was required.

  11. Coal Research

    NASA Technical Reports Server (NTRS)

    1986-01-01

    Coal slurries are "clean" pulverized coal mixed with oil or water. Significant fuel savings can be realized when using coal slurries. Advanced Fuels Technology (AFT) utilized a COSMIC program, (Calculation of Complex Chemical Equilibrium Compositions), which provides specific capabilities for determining combustion products. The company has developed a cleaning process that removes much of the mineral sulphur and ash from the coals.

  12. Rheological behavior of highly loaded cellulose nanocrystal/poly(vinyl alcohol) composite suspensions

    Treesearch

    Caitlin E. Meree; Gregory T. Schueneman; J. Carson Meredith; Meisha L. Shofner

    2016-01-01

    Recent emphasis on the pilot scale production of cellulosic nanomaterials has increased interest in the effective use of these materials as reinforcements for polymer composites. An important, enabling step to realizing the potential of cellulosic nanomaterials in their applications is the materials processing of CNC/polymer composites through multiple routes, i.e....

  13. Basic characteristics and realization of production system control

    NASA Astrophysics Data System (ADS)

    Cheng, Shaopeng; Shell, Richard; Hall, Ernest L.

    1992-11-01

    This paper analyzes the issues involved in developing an intelligent production control system. It describes the basic characteristics of a production control system and an effective design methodology to realize the production control functions. Petri net, subsystem and hierarchical control concepts are applied to a computer integrated material handling system (MHS). Some communication and interface requirements of the MHS are also considered in this paper. The control system solution is illustrated with an actual MHS operation case which indicates that a truly flexible and integrated production system can be realized with a Petri net operation model and a hierarchical control structure. The significance of this work is related to the different operation testing and evaluation requirements encountered in manufacturing.

  14. Acoustooptic linear algebra processors - Architectures, algorithms, and applications

    NASA Technical Reports Server (NTRS)

    Casasent, D.

    1984-01-01

    Architectures, algorithms, and applications for systolic processors are described with attention to the realization of parallel algorithms on various optical systolic array processors. Systolic processors for matrices with special structure and matrices of general structure, and the realization of matrix-vector, matrix-matrix, and triple-matrix products and such architectures are described. Parallel algorithms for direct and indirect solutions to systems of linear algebraic equations and their implementation on optical systolic processors are detailed with attention to the pipelining and flow of data and operations. Parallel algorithms and their optical realization for LU and QR matrix decomposition are specifically detailed. These represent the fundamental operations necessary in the implementation of least squares, eigenvalue, and SVD solutions. Specific applications (e.g., the solution of partial differential equations, adaptive noise cancellation, and optimal control) are described to typify the use of matrix processors in modern advanced signal processing.

  15. Metalorganic chemical vapor deposition of AlGaAs and InGaP heterojunction bipolar transistors

    NASA Astrophysics Data System (ADS)

    Pan, N.; Welser, R. E.; Lutz, C. R.; DeLuca, P. M.; Han, B.; Hong, K.

    2001-05-01

    Heterojunction bipolar transistors (HBT) are now beginning to be widely incorporated as power amplifiers, laser drivers, multiplexers, clock data recovery circuits, as well as transimpedance and broadband amplifiers in high performance millimeter wave circuits (MMICs). The increasing acceptance of this device is principally due to advancements in metalorganic chemical vapor deposition (MOCVD), device processing, and circuit design technologies. Many of the DC electrical characteristics of large area devices can be directly correlated to the DC performance of small area RF devices. A precise understanding of the growth parameters and their relationship to device characteristics is critical for ensuring the high degree of reproducibility required for low cost high-yield volume manufacturing. Significant improvements in the understanding of the MOCVD growth process have been realized through the implementation of statistical process control on the key HBT device parameters. This tool has been successfully used to maintain the high quality of the device characteristics in high-volume production of 4″ GaAs-based HBTs. There is a growing demand to migrate towards 6″ diameter wafer size due to the potential cost reductions and increased volume production that can be realized. Preliminary results, indicating good heterostructure layer characteristics, demonstrate the feasibility of 6″ InGaP-based HBT devices.

  16. Application of Atmospheric-Pressure Microwave Line Plasma for Low Temperature Process

    NASA Astrophysics Data System (ADS)

    Suzuki, Haruka; Nakano, Suguru; Itoh, Hitoshi; Sekine, Makoto; Hori, Masaru; Toyoda, Hirotaka

    2015-09-01

    Atmospheric pressure (AP) plasmas have been given much attention because of its high cost benefit and a variety of possibilities for industrial applications. In various kinds of plasma production technique, pulsed-microwave discharge plasma using slot antenna is attractive due to its ability of high-density and stable plasma production. In this plasma source, however, size of the plasma has been limited up to a few cm in length due to standing wave inside a waveguide. To solve this, we have proposed a newly-developed AP microwave plasma source that utilizes not standing wave but travelling wave. By using this plasma source, spatially-uniform AP line plasma with 40 cm in length was realized by pure helium discharge in 60 cm slot and with nitrogen gas additive of 1%. Furthermore, gas temperature as low as 400 K was realized in this device. In this study, as an example of low temperature processes, hydrophilic treatment of PET films was performed. Processing speed increased with pulse frequency and a water contact angle of ~20° was easily obtained within 5 s with no thermal damage to the substrate. To evaluate treatment-uniformity of long line length, PET films were treated by 90 cm slot-antenna plasma and uniform treatment performance was confirmed.

  17. Method for processing coal-enrichment waste with solid and volatile fuel inclusions

    NASA Astrophysics Data System (ADS)

    Khasanova, A. V.; Zhirgalova, T. B.; Osintsev, K. V.

    2017-10-01

    The method relates to the field of industrial heat and power engineering. It can be used in coal preparation plants for processing coal waste. This new way is realized to produce a loose ash residue directed to the production of silicate products and fuel gas in rotary kilns. The proposed method is associated with industrial processing of brown coal beneficiation waste. Waste is obtained by flotation separation of rock particles up to 13 mm in size from coal particles. They have in their composition both solid and volatile fuel inclusions (components). Due to the high humidity and significant rock content, low heat of combustion, these wastes are not used on energy boilers, they are stored in dumps polluting the environment.

  18. Prospects for applications of electron beams in processing of gas and oil hydrocarbons

    NASA Astrophysics Data System (ADS)

    Ponomarev, A. V.; Pershukov, V. A.; Smirnov, V. P.

    2015-12-01

    Waste-free processing of oil and oil gases can be based on electron-beam technologies. Their major advantage is an opportunity of controlled manufacturing of a wide range of products with a higher utility value at moderate temperatures and pressures. The work considers certain key aspects of electron beam technologies applied for the chain cracking of heavy crude oil, for the synthesis of premium gasoline from oil gases, and also for the hydrogenation, alkylation, and isomerization of unsaturated oil products. Electronbeam processing of oil can be embodied via compact mobile modules which are applicable for direct usage at distant oil and gas fields. More cost-effective and reliable electron accelerators should be developed to realize the potential of electron-beam technologies.

  19. Sown species richness and realized diversity can influence functioning of plant communities differently.

    PubMed

    Rychtecká, Terezie; Lanta, Vojtěch; Weiterová, Iva; Lepš, Jan

    2014-08-01

    Biodiversity-ecosystem functioning experiments (BEF) typically manipulate sown species richness and composition of experimental communities to study ecosystem functioning as a response to changes in diversity. If sown species richness is taken as a measure of diversity and aboveground biomass production as a measure of community functioning, then this relationship is usually found to be positive. The sown species richness can be considered the equivalent of a local species pool in natural communities. However, in addition to species richness, realized diversity is also an important community diversity component. Realized diversity is affected by environmental filtering and biotic interactions operating within a community. As both sown species richness and the realized diversity in BEF studies (as well as local species pool vs observed realized richness in natural communities) can differ markedly, so can their effects on the community functioning. We tested this assumption using two data sets: data from a short-term pot experiment and data from the long-term Jena biodiversity plot experiment. We considered three possible predictors of community functioning (aboveground biomass production): sown species richness, realized diversity (defined as inverse of Simpson dominance index), and survivor species richness. Sown species richness affected biomass production positively in all cases. Realized diversity as well as survivor species richness had positive effects on biomass in approximately half of cases. When realized diversity or survivor species richness was tested together with sown species richness, their partial effects were none or negative. Our results suggest that we can expect positive diversity-productivity relationship when the local species pool size is the decisive factor determining realized observed diversity; in other cases, the shape of the diversity-functioning relationship may be quite opposite.

  20. Design of Control System for Flexible Packaging Bags Palletizing Production Line Based on PLC

    NASA Astrophysics Data System (ADS)

    Zheng, Huiping; Chen, Lin; Zhao, Xiaoming; Liu, Zhanyang

    Flexible packaging bags palletizing production line is to put the bags in the required area according to particular order and size, in order to finish handling, storage, loading and unloading, transportation and other logistics work of goods. Flexible packaging bags palletizing line is composed of turning bags mechanism, shaping mechanism, indexing mechanism, marshalling mechanism, pushing bags mechanism, pressing bags mechanism, laminating mechanism, elevator, tray warehouse, tray conveyor and loaded tray conveyor. Whether the whole production line can smoothly run depends on each of the above equipment and precision control among them. In this paper the technological process and the control logic of flexible packaging bags palletizing production line is introduced. Palletizing process of the production line realized automation by means of a control system based on programmable logic controller (PLC). It has the advantages of simple structure, reliable and easy maintenance etc.

  1. Impact of nowcasting on the production and processing of agricultural crops. [in the US

    NASA Technical Reports Server (NTRS)

    Dancer, W. S.; Tibbitts, T. W.

    1973-01-01

    The value was studied of improved weather information and weather forecasting to farmers, growers, and agricultural processing industries in the United States. The study was undertaken to identify the production and processing operations that could be improved with accurate and timely information on changing weather patterns. Estimates were then made of the potential savings that could be realized with accurate information about the prevailing weather and short term forecasts for up to 12 hours. This weather information has been termed nowcasting. The growing, marketing, and processing operations of the twenty most valuable crops in the United States were studied to determine those operations that are sensitive to short-term weather forecasting. Agricultural extension specialists, research scientists, growers, and representatives of processing industries were consulted and interviewed. The value of the crops included in this survey and their production levels are given. The total value for crops surveyed exceeds 24 billion dollars and represents more than 92 percent of total U.S. crop value.

  2. [Advances in microbial production of alkaline polygalacturonate lyase and its application in clean production of textile industry].

    PubMed

    Liu, Long; Wang, Zhihao; Zhang, Dongxu; Li, Jianghua; Du, Guocheng; Chen, Jian

    2009-12-01

    We reviewed the microbial production of alkaline polygalacturonate lyase (PGL) and its application in the clean production of textile industry. Currently PGL is mainly produced by microbial fermentation and Bacillus sp. is an ideal wild strain for PGL production. Microbial PGL production was affected by many factors including the concentration and feeding mode of substrate, cell concentration, agitation speed, aeration rate, pH and temperature. Constructing the recombinant strain provided an effective alternative for PGL production, and the concentration of PGL produced by the recombinant Pichia pastoris reached 1305 U/mL in 10 m3 fermentor. The recombinant Pichia pastoris had the potential to reach the industrial production of PGL. PGL can be applied in bio-scouring process in the pre-treatment of cotton. Compared with the traditional alkaline cooking process, the application of PGL can protect fiber, improve the bio-scouring efficiency, decrease energy consumption and alleviate the environmental pollution. The future research focus will be the molecular directed evolution of PGL to make PGL more suitable for the application of PGL in bio-scouring process to realize the clean production of textile industry.

  3. Improving functional value of meat products.

    PubMed

    Zhang, Wangang; Xiao, Shan; Samaraweera, Himali; Lee, Eun Joo; Ahn, Dong U

    2010-09-01

    In recent years, much attention has been paid to develop meat and meat products with physiological functions to promote health conditions and prevent the risk of diseases. This review focuses on strategies to improve the functional value of meat and meat products. Value improvement can be realized by adding functional compounds including conjugated linoneleic acid, vitamin E, n3 fatty acids and selenium in animal diets to improve animal production, carcass composition and fresh meat quality. In addition, functional ingredients such as vegetable proteins, dietary fibers, herbs and spices, and lactic acid bacteria can be directly incorporated into meat products during processing to improve their functional value for consumers. Functional compounds, especially peptides, can also be generated from meat and meat products during processing such as fermentation, curing and aging, and enzymatic hydrolysis. This review further discusses the current status, consumer acceptance, and market for functional foods from the global viewpoints. Future prospects for functional meat and meat products are also discussed.

  4. Design Process Improvement for Electric CAR Harness

    NASA Astrophysics Data System (ADS)

    Sawatdee, Thiwarat; Chutima, Parames

    2017-06-01

    In an automobile parts design company, the customer satisfaction is one of the most important factors for product design. Therefore, the company employs all means to focus its product design process based on the various requirements of customers resulting in high number of design changes. The objective of this research is to improve the design process of the electric car harness that effects the production scheduling by using Fault Tree Analysis (FTA) and Failure Mode and Effect Analysis (FMEA) as the main tools. FTA is employed for root cause analysis and FMEA is used to ranking a High Risk Priority Number (RPN) which is shows the priority of factors in the electric car harness that have high impact to the design of the electric car harness. After the implementation, the improvements are realized significantly since the number of design change is reduced from 0.26% to 0.08%.

  5. Monitoring in situ in real time of resin infusion for thermoset composite structures

    NASA Astrophysics Data System (ADS)

    Faci, A.; Wang, P.; Cochrane, C.; Koncar, V.

    2017-10-01

    The presented work investigates changes in electrical resistance of embedded sensory yarns as a method to monitor the resin flow front position and curing degree of resin during manufacturing of composite structures by vacuum infusion technology. The sensor concept is based on Piezo-resistive sensors integrated to the flax fabric, having almost identical propriety and dimensions as the flax threads used for the production of reinforcements. In the first time sensors have been characterized and first measures of the resin infusion have been realized in order to demonstrate the feasibility of the proposed approach. Then, the measures in real time were realized with fibrous sensors added to the flax fabric (green composites) to monitor the flow front of resin. A large amount of data recorded, filtered, examined, analysed and processed in order to understand and to optimize the infusion and polymerization process.

  6. The fuzzy algorithm in the die casting mould for the application of multi-channel temperature control

    NASA Astrophysics Data System (ADS)

    Sun, Jin-gen; Chen, Yi; Zhang, Jia-nan

    2017-01-01

    Mould manufacturing is one of the most basic elements in the production chain of China. The mould manufacturing technology has become an important symbol to measure the level of a country's manufacturing industry. The die-casting mould multichannel intelligent temperature control method is studied by cooling water circulation, which uses fuzzy control to realize, aiming at solving the shortcomings of slow speed and big energy consumption during the cooling process of current die-casting mould. At present, the traditional PID control method is used to control the temperature, but it is difficult to ensure the control precision. While , the fuzzy algorithm is used to realize precise control of mould temperature in cooling process. The design is simple, fast response, strong anti-interference ability and good robustness. Simulation results show that the control method is completely feasible, which has higher control precision.

  7. Quality by control: Towards model predictive control of mammalian cell culture bioprocesses.

    PubMed

    Sommeregger, Wolfgang; Sissolak, Bernhard; Kandra, Kulwant; von Stosch, Moritz; Mayer, Martin; Striedner, Gerald

    2017-07-01

    The industrial production of complex biopharmaceuticals using recombinant mammalian cell lines is still mainly built on a quality by testing approach, which is represented by fixed process conditions and extensive testing of the end-product. In 2004 the FDA launched the process analytical technology initiative, aiming to guide the industry towards advanced process monitoring and better understanding of how critical process parameters affect the critical quality attributes. Implementation of process analytical technology into the bio-production process enables moving from the quality by testing to a more flexible quality by design approach. The application of advanced sensor systems in combination with mathematical modelling techniques offers enhanced process understanding, allows on-line prediction of critical quality attributes and subsequently real-time product quality control. In this review opportunities and unsolved issues on the road to a successful quality by design and dynamic control implementation are discussed. A major focus is directed on the preconditions for the application of model predictive control for mammalian cell culture bioprocesses. Design of experiments providing information about the process dynamics upon parameter change, dynamic process models, on-line process state predictions and powerful software environments seem to be a prerequisite for quality by control realization. © 2017 The Authors. Biotechnology Journal published by WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  8. Foundations of metabolic organization: coherence as a basis of computational properties in metabolic networks.

    PubMed

    Igamberdiev, A U

    1999-04-01

    Biological organization is based on the coherent energy transfer allowing for macromolecules to operate with high efficiency and realize computation. Computation is executed with virtually 100% efficiency via the coherent operation of molecular machines in which low-energy recognitions trigger energy-driven non-equilibrium dynamic processes. The recognition process is of quantum mechanical nature being a non-demolition measurement. It underlies the enzymatic conversion of a substrate into the product (an elementary metabolic phenomenon); the switching via separation of the direct and reverse routes in futile cycles provides the generation and complication of metabolic networks (coherence within cycles is maintained by the supramolecular organization of enzymes); the genetic level corresponding to the appearance of digital information is based on reflective arrows (catalysts realize their own self-reproduction) and operation of hypercycles. Every metabolic cycle via reciprocal regulation of both its halves can generate rhythms and spatial structures (resulting from the temporally organized depositions from the cycles). Via coherent events which percolate from the elementary submolecular level to organismic entities, self-assembly based on the molecular complementarity is realized and the dynamic informational field operating within the metabolic network is generated.

  9. A Comparison of Product Realization Frameworks

    DTIC Science & Technology

    1993-10-01

    software (integrated FrameMaker ). Also included are BOLD for on-line documentation delivery, printer/plotter support, and 18 network licensing support. AMPLE...are built with DSS. Documentation tools include an on-line information system (BOLD), text editing (Notepad), word processing (integrated FrameMaker ...within an application. FrameMaker is fully integrated with the Falcon Framework to provide consistent documentation capabilities within engineering

  10. Sustainable ranching: A new paradigm (Ganaderia Sustentable: Un Nuevo Paradigma)

    Treesearch

    Ivan Aguirre

    2006-01-01

    Today, rural communities need to take a new approach to decision-making and administration with regards to the causes and solutions to the processes of land deterioration. If the damages caused by drought, flood, and erosion were valued in monetary terms, opportunity costs, and value of human life, we would readily realize the benefits of investment in rural production...

  11. HARM processing techniques for MEMS and MOEMS devices using bonded SOI substrates and DRIE

    NASA Astrophysics Data System (ADS)

    Gormley, Colin; Boyle, Anne; Srigengan, Viji; Blackstone, Scott C.

    2000-08-01

    Silicon-on-Insulator (SOI) MEMS devices (1) are rapidly gaining popularity in realizing numerous solutions for MEMS, especially in the optical and inertia application fields. BCO recently developed a DRIE trench etch, utilizing the Bosch process, and refill process for high voltage dielectric isolation integrated circuits on thick SOI substrates. In this paper we present our most recently developed DRIE processes for MEMS and MOEMS devices. These advanced etch techniques are initially described and their integration with silicon bonding demonstrated. This has enabled process flows that are currently being utilized to develop optical router and filter products for fiber optics telecommunications and high precision accelerometers.

  12. JTEC Panel report on electronic manufacturing and packaging in Japan

    NASA Technical Reports Server (NTRS)

    Kelly, Michael J.; Boulton, William R. (Editor); Kukowski, John; Meieran, Gene; Pecht, Michael; Peeples, John; Tummala, Rao; Dehaemer, Michael J.; Holdridge, Geoff (Editor); Gamota, George

    1995-01-01

    This report summarizes the status of electronic manufacturing and packaging technology in Japan in comparison to that in the United States, and its impact on competition in electronic manufacturing in general. In addition to electronic manufacturing technologies, the report covers technology and manufacturing infrastructure, electronics manufacturing and assembly, quality assurance and reliability in the Japanese electronics industry, and successful product realization strategies. The panel found that Japan leads the United States in almost every electronics packaging technology. Japan clearly has achieved a strategic advantage in electronics production and process technologies. Panel members believe that Japanese competitors could be leading U.S. firms by as much as a decade in some electronics process technologies.

  13. Designing industrial yeasts for the consolidated bioprocessing of starchy biomass to ethanol

    PubMed Central

    Favaro, Lorenzo; Jooste, Tania; Basaglia, Marina; Rose, Shaunita H.; Saayman, Maryna; Görgens, Johann F.; Casella, Sergio; van Zyl, Willem H.

    2013-01-01

    Consolidated bioprocessing (CBP), which integrates enzyme production, saccharification and fermentation into a one step process, is a promising strategy for the effective ethanol production from cheap lignocellulosic and starchy materials. CBP requires a highly engineered microbial strain able to both hydrolyze biomass with enzymes produced on its own and convert the resulting simple sugars into high-titer ethanol. Recently, heterologous production of cellulose and starch-degrading enzymes has been achieved in yeast hosts, which has realized direct processing of biomass to ethanol. However, essentially all efforts aimed at the efficient heterologous expression of saccharolytic enzymes in yeast have involved laboratory strains and much of this work has to be transferred to industrial yeasts that provide the fermentation capacity and robustness desired for large scale bioethanol production. Specifically, the development of an industrial CBP amylolytic yeast would allow the one-step processing of low-cost starchy substrates into ethanol. This article gives insight in the current knowledge and achievements on bioethanol production from starchy materials with industrial engineered S. cerevisiae strains. PMID:22989992

  14. Design and operation of a continuous integrated monoclonal antibody production process.

    PubMed

    Steinebach, Fabian; Ulmer, Nicole; Wolf, Moritz; Decker, Lara; Schneider, Veronika; Wälchli, Ruben; Karst, Daniel; Souquet, Jonathan; Morbidelli, Massimo

    2017-09-01

    The realization of an end-to-end integrated continuous lab-scale process for monoclonal antibody manufacturing is described. For this, a continuous cultivation with filter-based cell-retention, a continuous two column capture process, a virus inactivation step, a semi-continuous polishing step (twin-column MCSGP), and a batch-wise flow-through polishing step were integrated and operated together. In each unit, the implementation of internal recycle loops allows to improve the performance: (a) in the bioreactor, to simultaneously increase the cell density and volumetric productivity, (b) in the capture process, to achieve improved capacity utilization at high productivity and yield, and (c) in the MCSGP process, to overcome the purity-yield trade-off of classical batch-wise bind-elute polishing steps. Furthermore, the design principles, which allow the direct connection of these steps, some at steady state and some at cyclic steady state, as well as straight-through processing, are discussed. The setup was operated for the continuous production of a commercial monoclonal antibody, resulting in stable operation and uniform product quality over the 17 cycles of the end-to-end integration. The steady-state operation was fully characterized by analyzing at the outlet of each unit at steady state the product titer as well as the process (HCP, DNA, leached Protein A) and product (aggregates, fragments) related impurities. © 2017 American Institute of Chemical Engineers Biotechnol. Prog., 33:1303-1313, 2017. © 2017 American Institute of Chemical Engineers.

  15. Results-driven approach to improving quality and productivity

    Treesearch

    John Dramm

    2000-01-01

    Quality control (QC) programs do not often realize their full potential. Elaborate and expensive QC programs can easily get side tracked by the process of building a program with promises of “Someday, this will all pay off.” Training employees in QC methods is no guarantee that quality will improve. Several documented cases show that such activity-centered efforts...

  16. Realizing Relevance: The Influence of Domain-Specific Information on Generation of New Knowledge through Integration in 4- to 8-Year-Old Children

    ERIC Educational Resources Information Center

    Bauer, Patricia J.; Larkina, Marina

    2017-01-01

    In accumulating knowledge, direct modes of learning are complemented by productive processes, including self-generation based on integration of separate episodes. Effects of the number of potentially relevant episodes on integration were examined in 4- to 8-year-olds (N = 121; racially/ethnically heterogeneous sample, English speakers, from large…

  17. Commissioning of a CERN Production and Analysis Facility Based on xrootd

    NASA Astrophysics Data System (ADS)

    Campana, Simone; van der Ster, Daniel C.; Di Girolamo, Alessandro; Peters, Andreas J.; Duellmann, Dirk; Coelho Dos Santos, Miguel; Iven, Jan; Bell, Tim

    2011-12-01

    The CERN facility hosts the Tier-0 of the four LHC experiments, but as part of WLCG it also offers a platform for production activities and user analysis. The CERN CASTOR storage technology has been extensively tested and utilized for LHC data recording and exporting to external sites according to experiments computing model. On the other hand, to accommodate Grid data processing activities and, more importantly, chaotic user analysis, it was realized that additional functionality was needed including a different throttling mechanism for file access. This paper will describe the xroot-based CERN production and analysis facility for the ATLAS experiment and in particular the experiment use case and data access scenario, the xrootd redirector setup on top of the CASTOR storage system, the commissioning of the system and real life experience for data processing and data analysis.

  18. Application of balancing methods in modeling the penicillin fermentation.

    PubMed

    Heijnen, J J; Roels, J A; Stouthamer, A H

    1979-12-01

    This paper shows the application of elementary balancing methods in combination with simple kinetic equations in the formulation of an unstructured model for the fed-batch process for the production of penicillin. The rate of substrate uptake is modeled with a Monod-type relationship. The specific penicillin production rate is assumed to be a function of growth rate. Hydrolysis of penicillin to penicilloic acid is assumed to be first order in penicillin. In simulations with the present model it is shown that the model, although assuming a strict relationship between specific growth rate and penicillin productivity, allows for the commonly observed lag phase in the penicillin concentration curve and the apparent separation between growth and production phase (idiophase-trophophase concept). Furthermore it is shown that the feed rate profile during fermentation is of vital importance in the realization of a high production rate throughout the duration of the fermentation. It is emphasized that the method of modeling presented may also prove rewarding for an analysis of fermentation processes other than the penicillin fermentation.

  19. Assessment Study on Sensors and Automation in the Industries of the Future. Reports on Industrial Controls, Information Processing, Automation, and Robotics

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bennett, Bonnie; Boddy, Mark; Doyle, Frank

    This report presents the results of an expert study to identify research opportunities for Sensors & Automation, a sub-program of the U.S. Department of Energy (DOE) Industrial Technologies Program (ITP). The research opportunities are prioritized by realizable energy savings. The study encompasses the technology areas of industrial controls, information processing, automation, and robotics. These areas have been central areas of focus of many Industries of the Future (IOF) technology roadmaps. This report identifies opportunities for energy savings as a direct result of advances in these areas and also recognizes indirect means of achieving energy savings, such as product quality improvement,more » productivity improvement, and reduction of recycle.« less

  20. Characteristics of products generated by selective sintering and stereolithography rapid prototyping processes

    NASA Technical Reports Server (NTRS)

    Cariapa, Vikram

    1993-01-01

    The trend in the modern global economy towards free market policies has motivated companies to use rapid prototyping technologies to not only reduce product development cycle time but also to maintain their competitive edge. A rapid prototyping technology is one which combines computer aided design with computer controlled tracking of focussed high energy source (eg. lasers, heat) on modern ceramic powders, metallic powders, plastics or photosensitive liquid resins in order to produce prototypes or models. At present, except for the process of shape melting, most rapid prototyping processes generate products that are only dimensionally similar to those of the desired end product. There is an urgent need, therefore, to enhance the understanding of the characteristics of these processes in order to realize their potential for production. Currently, the commercial market is dominated by four rapid prototyping processes, namely selective laser sintering, stereolithography, fused deposition modelling and laminated object manufacturing. This phase of the research has focussed on the selective laser sintering and stereolithography rapid prototyping processes. A theoretical model for these processes is under development. Different rapid prototyping sites supplied test specimens (based on ASTM 638-84, Type I) that have been measured and tested to provide a data base on surface finish, dimensional variation and ultimate tensile strength. Further plans call for developing and verifying the theoretical models by carefully designed experiments. This will be a joint effort between NASA and other prototyping centers to generate a larger database, thus encouraging more widespread usage by product designers.

  1. Life cycle energy and greenhouse gas profile of a process for the production of ammonium sulfate from nitrogen-fixing photosynthetic cyanobacteria.

    PubMed

    Razon, Luis F

    2012-03-01

    In this paper, an alternative means for nitrogen fixation that may consume less energy and release less greenhouse gases than the Haber-Bosch process is explored. A life-cycle assessment was conducted on a process to: culture the cyanobacterium, Anabaena sp. ATCC 33047, in open ponds; harvest the biomass and exopolysaccharides and convert these to biogas; strip and convert the ammonia from the biogas residue to ammonium sulfate; dry the ammonium sulfate solution to ammonium sulfate crystals and transport the finished product. The results suggest that substantial reductions in non-renewable energy use and greenhouse gas emissions may be realized. The study opens the possibility that Haber-Bosch ammonia may be replaced with ammonia from a biomass process which simultaneously generates renewable energy. The process is intrinsically safer than the Haber-Bosch process. However, there are trade-offs in terms of land use and possibly, water. Copyright © 2011 Elsevier Ltd. All rights reserved.

  2. RFID in the blood supply chain--increasing productivity, quality and patient safety.

    PubMed

    Briggs, Lynne; Davis, Rodeina; Gutierrez, Alfonso; Kopetsky, Matthew; Young, Kassandra; Veeramani, Raj

    2009-01-01

    As part of an overall design of a new, standardized RFID-enabled blood transfusion medicine supply chain, an assessment was conducted for two hospitals: the University of Iowa Hospital and Clinics (UIHC) and Mississippi Baptist Health System (MBHS). The main objectives of the study were to assess RFID technological and economic feasibility, along with possible impacts to productivity, quality and patient safety. A step-by-step process analysis focused on the factors contributing to process "pain points" (errors, inefficiency, product losses). A process re-engineering exercise produced blueprints of RFID-enabled processes to alleviate or eliminate those pain-points. In addition, an innovative model quantifying the potential reduction in adverse patient effects as a result of RFID implementation was created, allowing improvement initiatives to focus on process areas with the greatest potential impact to patient safety. The study concluded that it is feasible to implement RFID-enabled processes, with tangible improvements to productivity and safety expected. Based on a comprehensive cost/benefit model, it is estimated for a large hospital (UIHC) to recover investment from implementation within two to three years, while smaller hospitals may need longer to realize ROI. More importantly, the study estimated that RFID technology could reduce morbidity and mortality effects substantially among patients receiving transfusions.

  3. ITO-free white OLEDs on flexible substrates with enhanced light outcoupling

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rand, Barry

    2017-02-05

    The goal of this research is to further explore and integrate a number of innovative approaches we have developed that can overcome current bottlenecks to realize large-area ITO-free WOLEDs on flexible substrates, with processes and materials that are upscalable and amenable to low-cost production. In doing so, we provide an understanding of various loss mechanisms in OLEDs and how they can be extracted.

  4. CELSS research and development program

    NASA Technical Reports Server (NTRS)

    Bubenheim, David

    1990-01-01

    Research in Controlled Ecological Life Support Systems (CELSS) conducted by NASA indicate that plant based systems are feasible candidates for human support in space. Ames has responsibility for research and development, systems integration and control, and space flight experiment portions of the CELSS program. Important areas for development of new methods and technologies are biomass production, waste processing, water purification, air revitalization, and food processing. For the plant system, the approach was to identify the flexibility and response time for the food, water, and oxygen production, and carbon dioxide consumption processes. Tremendous increases in productivity, compared with terrestrial agriculture, were realized. Waste processing research emphasizes recycle (transformation) of human wastes, trash, and inedible biomass to forms usable as inputs to the plant production system. Efforts to improve efficiency of the plant system, select new CELSS crops for a balanced diet, and initiate closed system research with the Crop Growth Research Chambers continue. The System Control and Integration program goal is to insure orchestrated system operation of the biological, physical, and chemical operation of the biological, physical, and chemical component processors of the CELSS. Space flight studies are planned to verify adequate operation of the system in reduced gravity or microgravity environments.

  5. A Survey of Applications and Research in Integrated Design Systems Technology

    NASA Technical Reports Server (NTRS)

    1998-01-01

    The initial part of the study was begun with a combination of literature searches, World Wide Web searches, and contacts with individuals and companies who were known to members of our team to have an interest in topics that seemed to be related to our study. There is a long list of such topics, such as concurrent engineering, design for manufacture, life-cycle engineering, systems engineering, systems integration, systems design, design systems, integrated product and process approaches, enterprise integration, integrated product realization, and similar terms. These all capture, at least in part, the flavor of what we describe here as integrated design systems. An inhibiting factor in this inquiry was the absence of agreed terminology for the study of integrated design systems. It is common for the term to be applied to what are essentially augmented Computer-Aided Design (CAD) systems, which are integrated only to the extent that agreements have been reached to attach proprietary extensions to proprietary CAD programs. It is also common for some to use the term integrated design systems to mean a system that applies only, or mainly, to the design phase of a product life cycle. It is likewise common for many of the terms listed earlier to be used as synonyms for integrated design systems. We tried to avoid this ambiguity by adopting the definition of integrated design systems that is implied in the introductory notes that we provided to our contacts, cited earlier. We thus arrived at this definition: Integrated Design Systems refers to the integration of the different tools and processes that comprise the engineering, of complex systems. It takes a broad view of the engineering of systems, to include consideration of the entire product realization process and the product life cycle. An important aspect of integrated design systems is the extent to which they integrate existing, "islands of automation" into a comprehensive design and product realization environment. As the study progressed, we relied increasingly upon a networking approach to lead us to new information. The departure point for such searches often was a government-sponsored project or a company initiative. The advantage of this approach was that short conversations with knowledgeable persons would usually cut through confusion over differences of terminology, thereby somewhat reducing the search space of the study. Even so, it was not until late in our eight-month inquiry that we began to see signs of convergence of the search, in the sense that a number of the latest inquiries began to turn up references to earlier contacts. As suggested above, this convergence often occurred with respect to particular government or company projects.

  6. [Complex technology for water and wastewater disinfection and its industrial realization in prototype unit].

    PubMed

    Arakcheev, E N; Brunman, V E; Brunman, M V; Konyashin, A V; Dyachenko, V A; Petkova, A P

    Usage of complex automated electrolysis unit for drinking water disinfection and wastewater oxidation and coagulation is scoped, its ecological and energy efficiency is shown. Properties of technological process of anolyte production using membrane electrolysis of brine for water disinfection in municipal pipelines and potassium ferrate production using electrochemical dissolution of iron anode in NaOH solution for usage in purification plants are listed. Construction of modules of industrial prototype for anolyte and ferrate production and applied aspects of automation of complex electrolysis unit are proved. Results of approbation of electrolytic potassium ferrate for drinking water disinfection and wastewater, rain water and environmental water oxidation and coagulation are shown.

  7. Creation of system of computer-aided design for technological objects

    NASA Astrophysics Data System (ADS)

    Zubkova, T. M.; Tokareva, M. A.; Sultanov, N. Z.

    2018-05-01

    Due to the competition in the market of process equipment, its production should be flexible, retuning to various product configurations, raw materials and productivity, depending on the current market needs. This process is not possible without CAD (computer-aided design). The formation of CAD begins with planning. Synthesizing, analyzing, evaluating, converting operations, as well as visualization and decision-making operations, can be automated. Based on formal description of the design procedures, the design route in the form of an oriented graph is constructed. The decomposition of the design process, represented by the formalized description of the design procedures, makes it possible to make an informed choice of the CAD component for the solution of the task. The object-oriented approach allows us to consider the CAD as an independent system whose properties are inherited from the components. The first step determines the range of tasks to be performed by the system, and a set of components for their implementation. The second one is the configuration of the selected components. The interaction between the selected components is carried out using the CALS standards. The chosen CAD / CAE-oriented approach allows creating a single model, which is stored in the database of the subject area. Each of the integration stages is implemented as a separate functional block. The transformation of the CAD model into the model of the internal representation is realized by the block of searching for the geometric parameters of the technological machine, in which the XML-model of the construction is obtained on the basis of the feature method from the theory of image recognition. The configuration of integrated components is divided into three consecutive steps: configuring tasks, components, interfaces. The configuration of the components is realized using the theory of "soft computations" using the Mamdani fuzzy inference algorithm.

  8. A risk analysis for production processes with disposable bioreactors.

    PubMed

    Merseburger, Tobias; Pahl, Ina; Müller, Daniel; Tanner, Markus

    2014-01-01

    : Quality management systems are, as a rule, tightly defined systems that conserve existing processes and therefore guarantee compliance with quality standards. But maintaining quality also includes introducing new enhanced production methods and making use of the latest findings of bioscience. The advances in biotechnology and single-use manufacturing methods for producing new drugs especially impose new challenges on quality management, as quality standards have not yet been set. New methods to ensure patient safety have to be established, as it is insufficient to rely only on current rules. A concept of qualification, validation, and manufacturing procedures based on risk management needs to be established and realized in pharmaceutical production. The chapter starts with an introduction to the regulatory background of the manufacture of medicinal products. It then continues with key methods of risk management. Hazards associated with the production of medicinal products with single-use equipment are described with a focus on bioreactors, storage containers, and connecting devices. The hazards are subsequently evaluated and criteria for risk evaluation are presented. This chapter concludes with aspects of industrial application of quality risk management.

  9. Disassembly factories for electrical and electronic products to recover resources in product and material cycles.

    PubMed

    Basdere, Bahadir; Seliger, Guenther

    2003-12-01

    Cycle economy as a paradigm for industry in the 21st century depends on the economical and ecological treatment of limited resources. The objective is to achieve more use with fewer resources to increase the use-productivity of these resources. The European Union, aware of the adverse environmental impacts associated with electrical and electronic consumer goods in particular, has passed legislation regulating their appropriate end-of-life treatment. Adaptation processes, including essential disassembly and re-assembly operations, contribute significantly toward the economical fulfillment of these new legal requirements. Typically, the disassembly of used products is characterized by a high rate of manual operations, wide variety of product types, and unknown product properties. To cope with such demands, life cycle units or product accompanying information systems, are being developed and used for acquiring data about a specific product throughout its life cycle to aid in determining the level of product deterioration. Modular disassembly processes and tools have been developed and realized to enable the handling of multiple productvariants. They are being implemented in prototypical hybrid disassembly systemsfor large- and small-size electrical and electronic consumer goods.

  10. Customer satisfaction planning and industrial engineering move hospital towards in-house stockless program.

    PubMed

    Burton, R; Mauk, D

    1993-03-01

    By integrating customer satisfaction planning and industrial engineering techniques when examining internal costs and efficiencies, materiel managers are able to better realize what concepts will best meet their customers' needs. Defining your customer(s), applying industrial engineering techniques, completing work sampling studies, itemizing recommendations and benefits to each alternative, performing feasibility and cost-analysis matrixes and utilizing resources through productivity monitoring will get you on the right path toward selecting concepts to use. This article reviews the above procedures as they applied to one hospital's decision-making process to determine whether to incorporate a stockless inventory program. Through an analysis of customer demand, the hospital realized that stockless was the way to go, but not by outsourcing the function--the hospital incorporated an in-house stockless inventory program.

  11. A Petri Net-Based Software Process Model for Developing Process-Oriented Information Systems

    NASA Astrophysics Data System (ADS)

    Li, Yu; Oberweis, Andreas

    Aiming at increasing flexibility, efficiency, effectiveness, and transparency of information processing and resource deployment in organizations to ensure customer satisfaction and high quality of products and services, process-oriented information systems (POIS) represent a promising realization form of computerized business information systems. Due to the complexity of POIS, explicit and specialized software process models are required to guide POIS development. In this chapter we characterize POIS with an architecture framework and present a Petri net-based software process model tailored for POIS development with consideration of organizational roles. As integrated parts of the software process model, we also introduce XML nets, a variant of high-level Petri nets as basic methodology for business processes modeling, and an XML net-based software toolset providing comprehensive functionalities for POIS development.

  12. Process for recovering products from oil shale

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jacobs, H.R.; Udell, K.S.

    A process is claimed for recovering hydrocarbon products from a body of fragmented or rubblized oil shale. The process includes initiating a combustion zone adjacent the lower end of a body of oil shale and using the thermal energy therefrom for volatilizing the shale oil from the oil shale above the combustion front. Improved recovery of hydrocarbon products is realized by refluxing the heavier fractions in the volatilized shale oil. The heavier fractions are refluxed by condensing the heavier fractions and allowing the resulting condensate to flow downwardly toward the combustion front. Thermal energy from the combustion zone cracks themore » condensate producing additional lower molecular weight fractions and a carbonaceous residue. The carbonaceous residue is burned in the combustion front to supply the thermal energy. The temperature of the combustion front is maintained by regulating input of oxygen to the combustion zone. The process also includes sweeping the volatilized products from the rubblized oil shale with a noncombustible gas. The flow rate of sweep gas is also controlled to regulate the temperature of the combustion front. The recovered products can be enriched with hydrogen by using water vapor as part of the noncombustible sweep gas and cracking the water vapor with the hot carbon in the combustion front to produce hydrogen and an oxide of carbon.« less

  13. Three-dimensional femtosecond laser processing for lab-on-a-chip applications

    NASA Astrophysics Data System (ADS)

    Sima, Felix; Sugioka, Koji; Vázquez, Rebeca Martínez; Osellame, Roberto; Kelemen, Lóránd; Ormos, Pal

    2018-02-01

    The extremely high peak intensity associated with ultrashort pulse width of femtosecond laser allows us to induce nonlinear interaction such as multiphoton absorption and tunneling ionization with materials that are transparent to the laser wavelength. More importantly, focusing the femtosecond laser beam inside the transparent materials confines the nonlinear interaction only within the focal volume, enabling three-dimensional (3D) micro- and nanofabrication. This 3D capability offers three different schemes, which involve undeformative, subtractive, and additive processing. The undeformative processing preforms internal refractive index modification to construct optical microcomponents including optical waveguides. Subtractive processing can realize the direct fabrication of 3D microfluidics, micromechanics, microelectronics, and photonic microcomponents in glass. Additive processing represented by two-photon polymerization enables the fabrication of 3D polymer micro- and nanostructures for photonic and microfluidic devices. These different schemes can be integrated to realize more functional microdevices including lab-on-a-chip devices, which are miniaturized laboratories that can perform reaction, detection, analysis, separation, and synthesis of biochemical materials with high efficiency, high speed, high sensitivity, low reagent consumption, and low waste production. This review paper describes the principles and applications of femtosecond laser 3D micro- and nanofabrication for lab-on-a-chip applications. A hybrid technique that promises to enhance functionality of lab-on-a-chip devices is also introduced.

  14. Production of the potential sweetener 5-ketofructose from fructose in fed-batch cultivation with Gluconobacter oxydans.

    PubMed

    Herweg, Elena; Schöpping, Marie; Rohr, Katja; Siemen, Anna; Frank, Oliver; Hofmann, Thomas; Deppenmeier, Uwe; Büchs, Jochen

    2018-07-01

    Sweeteners improve the dietary properties of many foods. A candidate for a new natural sweetener is 5-ketofructose. In this study a fed-batch process for the production of 5-ketofructose was developed. A Gluconobacter oxydans strain overexpressing a fructose dehydrogenase from G. japonicus was used and the sensory properties of 5-ketofructose were analyzed. The compound showed an identical sweet taste quality as fructose and a similar intrinsic sweet threshold concentration of 16.4 mmol/L. The production of 5-ketofructose was characterized online by monitoring of the respiration activity in shake flasks. Pulsed and continuous fructose feeding was realized in 2 L stirred tank reactors and maximum fructose consumption rates were determined. 5-Ketofructose concentrations of up to 489 g/L, product yields up to 0.98 g 5-KF /g fructose and space time yields up to 8.2 g/L/h were reached highlighting the potential of the presented process. Copyright © 2018 Elsevier Ltd. All rights reserved.

  15. From 3D view to 3D print

    NASA Astrophysics Data System (ADS)

    Dima, M.; Farisato, G.; Bergomi, M.; Viotto, V.; Magrin, D.; Greggio, D.; Farinato, J.; Marafatto, L.; Ragazzoni, R.; Piazza, D.

    2014-08-01

    In the last few years 3D printing is getting more and more popular and used in many fields going from manufacturing to industrial design, architecture, medical support and aerospace. 3D printing is an evolution of bi-dimensional printing, which allows to obtain a solid object from a 3D model, realized with a 3D modelling software. The final product is obtained using an additive process, in which successive layers of material are laid down one over the other. A 3D printer allows to realize, in a simple way, very complex shapes, which would be quite difficult to be produced with dedicated conventional facilities. Thanks to the fact that the 3D printing is obtained superposing one layer to the others, it doesn't need any particular work flow and it is sufficient to simply draw the model and send it to print. Many different kinds of 3D printers exist based on the technology and material used for layer deposition. A common material used by the toner is ABS plastics, which is a light and rigid thermoplastic polymer, whose peculiar mechanical properties make it diffusely used in several fields, like pipes production and cars interiors manufacturing. I used this technology to create a 1:1 scale model of the telescope which is the hardware core of the space small mission CHEOPS (CHaracterising ExOPlanets Satellite) by ESA, which aims to characterize EXOplanets via transits observations. The telescope has a Ritchey-Chrétien configuration with a 30cm aperture and the launch is foreseen in 2017. In this paper, I present the different phases for the realization of such a model, focusing onto pros and cons of this kind of technology. For example, because of the finite printable volume (10×10×12 inches in the x, y and z directions respectively), it has been necessary to split the largest parts of the instrument in smaller components to be then reassembled and post-processed. A further issue is the resolution of the printed material, which is expressed in terms of layers thickness, in the Z direction, and in drop-per-inch, in X and Y directions. 3D printing is also an easy and quick production technique, which can become useful in the ad-hoc realization of mechanical components for optical setups to be used in a laboratory for new concept studies and validation, reducing the manufacturing time. With this technique, indeed, it is possible to realize in few hours custom-made mechanical parts, without any specific knowledge and expertise in tool machinery, as long as the resolution and size are compliant with the requirements.

  16. The research on construction and application of machining process knowledge base

    NASA Astrophysics Data System (ADS)

    Zhao, Tan; Qiao, Lihong; Qie, Yifan; Guo, Kai

    2018-03-01

    In order to realize the application of knowledge in machining process design, from the perspective of knowledge in the application of computer aided process planning(CAPP), a hierarchical structure of knowledge classification is established according to the characteristics of mechanical engineering field. The expression of machining process knowledge is structured by means of production rules and the object-oriented methods. Three kinds of knowledge base models are constructed according to the representation of machining process knowledge. In this paper, the definition and classification of machining process knowledge, knowledge model, and the application flow of the process design based on the knowledge base are given, and the main steps of the design decision of the machine tool are carried out as an application by using the knowledge base.

  17. Development of a process for high capacity-arc heater production of silicon

    NASA Technical Reports Server (NTRS)

    Reed, W. H.; Meyer, T. N.; Fey, M. G.; Harvey, F. J.; Arcella, F. G.

    1978-01-01

    The realization of low cost, electric power from large-area silicon, photovoltaic arrays will depend on the development of new methods for large capacity production of solar grade (SG) silicon with a cost of less than $10 per kilogram by 1986 (established Department of Energy goal). The objective of the program is to develop a method to produce SG silicon in large quantities based on the high temperature-sodium reduction of silicon tetrachloride (SiCl4) to yield molten silicon and the coproduct salt vapor (NaCl). Commercial ac electric arc heaters will be utilized to provide a hyper-heated mixture of argon and hydrogen which will furnish the required process energy. The reactor is designed for a nominal silicon flow rate of 45 kg/hr. Analyses and designs have been conducted to evaluate the process and complete the initial design of the experimental verification unit.

  18. Realization of Complex Onsets by Pediatric Users of Cochlear Implants

    ERIC Educational Resources Information Center

    Chin, Steven B.

    2006-01-01

    This study examined variations in English complex onset realizations by children who use cochlear implants. Data consisted of 227 productions of two-segment onset clusters from 12 children. In general, onset cluster realizations of children with cochlear implants did not differ markedly from those reported for children with normal hearing: null…

  19. [Quality by design approaches for pharmaceutical development and manufacturing of Chinese medicine].

    PubMed

    Xu, Bing; Shi, Xin-Yuan; Wu, Zhi-Sheng; Zhang, Yan-Ling; Wang, Yun; Qiao, Yan-Jiang

    2017-03-01

    The pharmaceutical quality was built by design, formed in the manufacturing process and improved during the product's lifecycle. Based on the comprehensive literature review of pharmaceutical quality by design (QbD), the essential ideas and implementation strategies of pharmaceutical QbD were interpreted. Considering the complex nature of Chinese medicine, the "4H" model was innovated and proposed for implementing QbD in pharmaceutical development and industrial manufacture of Chinese medicine product. "4H" corresponds to the acronym of holistic design, holistic information analysis, holistic quality control, and holistic process optimization, which is consistent with the holistic concept of Chinese medicine theory. The holistic design aims at constructing both the quality problem space from the patient requirement and the quality solution space from multidisciplinary knowledge. Holistic information analysis emphasizes understanding the quality pattern of Chinese medicine by integrating and mining multisource data and information at a relatively high level. The batch-to-batch quality consistence and manufacturing system reliability can be realized by comprehensive application of inspective quality control, statistical quality control, predictive quality control and intelligent quality control strategies. Holistic process optimization is to improve the product quality and process capability during the product lifecycle management. The implementation of QbD is useful to eliminate the ecosystem contradictions lying in the pharmaceutical development and manufacturing process of Chinese medicine product, and helps guarantee the cost effectiveness. Copyright© by the Chinese Pharmaceutical Association.

  20. A study on the optics of copper indium gallium (di)selenide (CIGS) solar cells with ultra-thin absorber layers.

    PubMed

    Xu, Man; Wachters, Arthur J H; van Deelen, Joop; Mourad, Maurice C D; Buskens, Pascal J P

    2014-03-10

    We present a systematic study of the effect of variation of the zinc oxide (ZnO) and copper indium gallium (di)selenide (CIGS) layer thickness on the absorption characteristics of CIGS solar cells using a simulation program based on finite element method (FEM). We show that the absorption in the CIGS layer does not decrease monotonically with its layer thickness due to interference effects. Ergo, high precision is required in the CIGS production process, especially when using ultra-thin absorber layers, to accurately realize the required thickness of the ZnO, cadmium sulfide (CdS) and CIGS layer. We show that patterning the ZnO window layer can strongly suppress these interference effects allowing a higher tolerance in the production process.

  1. A System-Oriented Approach for the Optimal Control of Process Chains under Stochastic Influences

    NASA Astrophysics Data System (ADS)

    Senn, Melanie; Schäfer, Julian; Pollak, Jürgen; Link, Norbert

    2011-09-01

    Process chains in manufacturing consist of multiple connected processes in terms of dynamic systems. The properties of a product passing through such a process chain are influenced by the transformation of each single process. There exist various methods for the control of individual processes, such as classical state controllers from cybernetics or function mapping approaches realized by statistical learning. These controllers ensure that a desired state is obtained at process end despite of variations in the input and disturbances. The interactions between the single processes are thereby neglected, but play an important role in the optimization of the entire process chain. We divide the overall optimization into two phases: (1) the solution of the optimization problem by Dynamic Programming to find the optimal control variable values for each process for any encountered end state of its predecessor and (2) the application of the optimal control variables at runtime for the detected initial process state. The optimization problem is solved by selecting adequate control variables for each process in the chain backwards based on predefined quality requirements for the final product. For the demonstration of the proposed concept, we have chosen a process chain from sheet metal manufacturing with simplified transformation functions.

  2. Instrumentation, metrology, and standards: key elements for the future of nanomanufacturing

    NASA Astrophysics Data System (ADS)

    Postek, Michael T.; Lyons, Kevin

    2007-09-01

    Nanomanufacturing is the essential bridge between the discoveries of nanoscience and real world nanotech products and is the vehicle by which the Nation and the World will realize the promise of major technological innovation across a spectrum of products that will affect virtually every industrial sector. For nanotech products to achieve the broad impacts envisioned, they must be manufactured in market-appropriate quantities in a reliable, repeatable, economical and commercially viable manner. In addition, they must be manufactured so that environmental and human health concerns are met, worker safety issues are appropriately assessed and handled, and liability issues are addressed. Critical to this realization of robust nanomanufacturing is the development of the necessary instrumentation, metrology, and standards. Integration of the instruments, their interoperability, and appropriate information management are also critical elements that must be considered for viable nanomanufacturing. Advanced instrumentation, metrology and standards will allow the physical dimensions, properties, functionality, and purity of the materials, processes, tools, systems, products, and emissions that will constitute nanomanufacturing to be measured and characterized. This will in turn enable production to be scaleable, controllable, predictable, and repeatable to meet market needs. If a nano-product cannot be measured it cannot be manufactured; additionally if that product cannot be made safely it should not be manufactured. This presentation introduces the Instrumentation, Metrology, and Standards for Nanomanufacturing Conference at the 2007 SPIE Optics and Photonics. This conference will become the leading forum for the exchange of foundational information and discussion of instrumentation, metrology and standards which are key elements for the success of nanomanufacturing.

  3. Large-Eddy Simulation of an n-Dodecane Spray Flame Under Different Ambient Oxygen Conditions

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pei, Yuanjiang; Hu, Bing; Som, Sibendu

    2016-03-16

    An n-dodecane spray flame was simulated using a dynamic structure large eddy simulation (LES) model coupled with a detailed chemistry combustion model to understand the ignition processes and the quasi-steady state flame structures. This study focuses on the effect of different ambient oxygen concentrations, 13%, 15% and 21% at an ambient temperature of 900 K and an ambient density of 22.8 kg/m3, which are typical diesel-engine relevant conditions with different levels of exhaust gas recirculation (EGR). The liquid spray was treated with a traditional Lagrangian method. A 103-species skeletal mechanism was used for the n-dodecane chemical kinetic model. It ismore » observed that the main ignitions occur in rich mixture and the flames are thickened around 35 to 40 mm off the spray axis due to the enhanced turbulence induced by the strong recirculation upstream, just behind the head of the flames at different oxygen concentrations. At 1 ms after the start of injection, the soot production is dominated by the broader region of high temperature in rich mixture instead of the stronger oxidation of the high peak temperature. Multiple realizations were performed for the 15% O2 condition to understand the realization to realization variation and to establish best practices for ensembleaveraging diesel spray flames. Two indexes are defined. The structure-similarity index analysis suggests at least 5 realizations are needed to obtain 99% similarity for mixture fraction if the average of 16 realizations are used as the target at 0.8 ms. However, this scenario may be different for different scalars of interest. It is found that 6 realizations would be enough to reach 99% of similarity for temperature, while 8 and 14 realizations are required to achieve 99% similarity for soot and OH mass fraction, respectively. Similar findings are noticed at 1 ms. More realizations are needed for the magnitude-similarity index for the similar level of similarity as the structure-similarity index« less

  4. A novel process for production of spherical PBT powders and their processing behavior during laser beam melting

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Schmidt, Jochen, E-mail: jochen.schmidt@fau.de; Sachs, Marius; Fanselow, Stephanie

    2016-03-09

    Additive manufacturing processes like laser beam melting of polymers are established for production of prototypes and individualized parts. The transfer to other areas of application and to serial production is currently hindered by the limited availability of polymer powders with good processability. Within this contribution a novel process route for the production of spherical polymer micron-sized particles of good flowability has been established and applied to produce polybutylene terephthalate (PBT) powders. Moreover, the applicability of the PBT powders in selective laser beam melting and the dependencies of process parameters on device properties will be outlined. First, polymer micro particles aremore » produced by a novel wet grinding method. To improve the flowability the produced particles the particle shape is optimized by rounding in a heated downer reactor. A further improvement of flowability of the cohesive spherical PBT particles is realized by dry coating. An improvement of flowability by a factor of about 5 is achieved by subsequent rounding of the comminution product and dry-coating as proven by tensile strength measurements of the powders. The produced PBT powders were characterized with respect to their processability. Therefore thermal, rheological, optical and bulk properties were analyzed. Based on these investigations a range of processing parameters was derived. Parameter studies on thin layers, produced in a selective laser melting system, were conducted. Hence appropriate parameters for processing the PBT powders by laser beam melting, like building chamber temperature, scan speed and laser power have been identified.« less

  5. Eigensystem realization algorithm user's guide forVAX/VMS computers: Version 931216

    NASA Technical Reports Server (NTRS)

    Pappa, Richard S.

    1994-01-01

    The eigensystem realization algorithm (ERA) is a multiple-input, multiple-output, time domain technique for structural modal identification and minimum-order system realization. Modal identification is the process of calculating structural eigenvalues and eigenvectors (natural vibration frequencies, damping, mode shapes, and modal masses) from experimental data. System realization is the process of constructing state-space dynamic models for modern control design. This user's guide documents VAX/VMS-based FORTRAN software developed by the author since 1984 in conjunction with many applications. It consists of a main ERA program and 66 pre- and post-processors. The software provides complete modal identification capabilities and most system realization capabilities.

  6. Spontaneous emergence of catalytic cycles with colloidal spheres

    NASA Astrophysics Data System (ADS)

    Zeravcic, Zorana; Brenner, Michael P.

    2017-04-01

    Colloidal particles endowed with specific time-dependent interactions are a promising route for realizing artificial materials that have the properties of living ones. Previous work has demonstrated how this system can give rise to self-replication. Here, we introduce the process of colloidal catalysis, in which clusters of particles catalyze the creation of other clusters through templating reactions. Surprisingly, we find that simple templating rules generically lead to the production of huge numbers of clusters. The templating reactions among this sea of clusters give rise to an exponentially growing catalytic cycle, a specific realization of Dyson’s notion of an exponentially growing metabolism. We demonstrate this behavior with a fixed set of interactions between particles chosen to allow a catalysis of a specific six-particle cluster from a specific seven-particle cluster, yet giving rise to the catalytic production of a sea of clusters of sizes between 2 and 11 particles. The fact that an exponentially growing cycle emerges naturally from such a simple scheme demonstrates that the emergence of exponentially growing metabolisms could be simpler than previously imagined.

  7. Integrated mild gasification processing at the Homer City Electric Power Generating Station site. Final report, July 1989--June 1993

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Battista, J.J.; Zawadzki, E.A.

    1993-07-01

    A new process for the production of commercial grade coke, char, and carbon products has been evaluated by Penelec/NYSEG. The process, developed by Coal Technology Corporation, CTC, utilizes a unique screw reactor to produce a devolatilized char from a wide variety of coals for the production of commercial grade coke for use in blast furnaces, foundries, and other processes requiring high quality coke. This process is called the CTC Mild Gasification Process (MGP). The process economics are significantly enhanced by integrating the new technology into an existing power generating complex. Cost savings are realized by the coke producer, the cokemore » user, and the electric utility company. Site specific economic studies involving the Homer City Generating Station site in Western Pennsylvania, confirmed that an integrated MGP at the Homer City site, using coal fines produced at the Homer City Coal Preparation Plant, would reduce capital and operating costs significantly and would enable the HC Owners to eliminate thermal dryers, obtain low cost fuel in the form of combustible gases and liquids, and obtain lower cost replacement coal on the spot market. A previous report, identified as the Interim Report on the Project, details the technical and economic studies.« less

  8. Recent progress in continuous and semi-continuous processing of solid oral dosage forms: a review.

    PubMed

    Teżyk, Michał; Milanowski, Bartłomiej; Ernst, Andrzej; Lulek, Janina

    2016-08-01

    Continuous processing is an innovative production concept well known and successfully used in other industries for many years. The modern pharmaceutical industry is facing the challenge of transition from a traditional manufacturing approach based on batch-wise production to a continuous manufacturing model. The aim of this article is to present technological progress in manufacturing based on continuous and semi-continuous processing of the solid oral dosage forms. Single unit processes possessing an alternative processing pathway to batch-wise technology or, with some modification, an altered approach that may run continuously, and are thus able to seamlessly switch to continuous manufacturing are briefly presented. Furthermore, the concept of semi-continuous processing is discussed. Subsequently, more sophisticated production systems created by coupling single unit processes and comprising all the steps of production, from powder to final dosage form, were reviewed. Finally, attempts of end-to-end production approach, meaning the linking of continuous synthesis of API from intermediates with the production of final dosage form, are described. There are a growing number of scientific articles showing an increasing interest in changing the approach to the production of pharmaceuticals in recent years. Numerous scientific publications are a source of information on the progress of knowledge and achievements of continuous processing. These works often deal with issues of how to modify or replace the unit processes in order to enable seamlessly switching them into continuous processing. A growing number of research papers concentrate on integrated continuous manufacturing lines in which the production concept of "from powder to tablet" is realized. Four main domains are under investigation: influence of process parameters on intermediates or final dosage forms properties, implementation of process analytical tools, control-managing system responsible for keeping continuous materials flow through the whole manufacturing process and the development of new computational methods to assess or simulate these new manufacturing techniques. The attempt to connect the primary and secondary production steps proves that development of continuously operating lines is possible. A mind-set change is needed to be able to face, and fully assess, the advantages and disadvantages of switching from batch to continuous mode production.

  9. Controlling high-throughput manufacturing at the nano-scale

    NASA Astrophysics Data System (ADS)

    Cooper, Khershed P.

    2013-09-01

    Interest in nano-scale manufacturing research and development is growing. The reason is to accelerate the translation of discoveries and inventions of nanoscience and nanotechnology into products that would benefit industry, economy and society. Ongoing research in nanomanufacturing is focused primarily on developing novel nanofabrication techniques for a variety of applications—materials, energy, electronics, photonics, biomedical, etc. Our goal is to foster the development of high-throughput methods of fabricating nano-enabled products. Large-area parallel processing and highspeed continuous processing are high-throughput means for mass production. An example of large-area processing is step-and-repeat nanoimprinting, by which nanostructures are reproduced again and again over a large area, such as a 12 in wafer. Roll-to-roll processing is an example of continuous processing, by which it is possible to print and imprint multi-level nanostructures and nanodevices on a moving flexible substrate. The big pay-off is high-volume production and low unit cost. However, the anticipated cost benefits can only be realized if the increased production rate is accompanied by high yields of high quality products. To ensure product quality, we need to design and construct manufacturing systems such that the processes can be closely monitored and controlled. One approach is to bring cyber-physical systems (CPS) concepts to nanomanufacturing. CPS involves the control of a physical system such as manufacturing through modeling, computation, communication and control. Such a closely coupled system will involve in-situ metrology and closed-loop control of the physical processes guided by physics-based models and driven by appropriate instrumentation, sensing and actuation. This paper will discuss these ideas in the context of controlling high-throughput manufacturing at the nano-scale.

  10. Web-based information system design of agricultural management towards self-sufficiency local food in North Aceh

    NASA Astrophysics Data System (ADS)

    Salahuddin; Husaini; Anwar

    2018-01-01

    The agricultural sector, especially food crops and horticulture, is one of the sectors driving regional economic pillars in Aceh Utara Regency of Aceh Province. Some agricultural products and food crops that become excellent products in North Aceh regency are: rice, corn, peanuts, long beans, cassava and soybeans. The Local Government of North Aceh Regency has not been optimal in empowering and maximizing the potential of agriculture resources. One of the obstacles is caused by the North Aceh Regency Government does not have an adequate database and web information system/GIS (Geographic Information System) for data management of agricultural centre in North Aceh Regency. This research is expected to assist local government of North Aceh Regency in managing agriculture sector to realize local food independence the region in supporting national food security program. The method in this research is using waterfall method for designing and making information system by conducting sequential process starting from data collection stage, requirement analysis, design, coding, testing and implementation system. The result of this research is a web-based information system for the management of agriculture superior agricultural product centre in North Aceh. This application provides information mapping the location of agricultural superior product producers and mapping of potential locations for the development of certain commodities in North Aceh Regency region in realizing food self-sufficiency in the region.

  11. Pyrolysis Gas as a Renewable Reducing Agent for the Recycling of Zinc- and Lead-Bearing Residues: A Status Report

    NASA Astrophysics Data System (ADS)

    Pichler, C.; Antrekowitsch, J.

    2017-04-01

    The topic "Zero Waste" has been in existence for several years in the industry, and the metallurgical industry has also made efforts to reduce the amounts of residues occurring and have started several investigations to cut down on metallurgical by-products which have to be landfilled. Especially, the additional costs for CO2 emissions in different metallurgical steps have led to investigations into alternative carbon carriers. Charcoal has been identified to serve as an ideal substitute due its CO2-neutrality. For the applications of this renewable carbon carrier in metallurgical processes, charcoal production by means of a carbonization process needs to be optimized. As a by-product during the heating of agricultural wastes or wood by excluding air, pyrolysis gas occurs. Due to the existence of combustible compounds in this gas, an application as a reduction agent instead of fossil carbon carriers in metallurgy is possible. Based on the prevention of dumping metallurgical by-products, an investigation has been developed to treat zinc- and lead-containing materials. To realize this, a dedicated process concept has been designed and developed. As the main focuses, the usage of the pyrolysis gas from charcoal production for the Waelz kiln process and the recycling of zinc- and lead-containing Waelz slag, resulting from the processing of steel mill dust in a vertical retort, have to be mentioned. Within this research, the process concept was executed from laboratory-scale up to pilot-scale testing, described in this article.

  12. The Growth of Developmental Thought: Implications for a New Evolutionary Psychology

    PubMed Central

    Lickliter, Robert

    2009-01-01

    Evolution has come to be increasingly discussed in terms of changes in developmental processes rather than simply in terms of changes in gene frequencies. This shift is based in large part on the recognition that since all phenotypic traits arise during ontogeny as products of individual development, a primary basis for evolutionary change must be variations in the patterns and processes of development. Further, the products of development are epigenetic, not just genetic, and this is the case even when considering the evolutionary process. These insights have led investigators to reconsider the established notion of genes as the primary cause of development, opening the door to research programs focused on identifying how genetic and non-genetic factors coact to guide and constrain the process of development and its outcomes. I explore this growth of developmental thought and its implications for the achievement of a unified theory of heredity, development, and evolution and consider its implications for the realization of a new, developmentally-based evolutionary psychology. PMID:19956346

  13. Process Simulation of Aluminium Sheet Metal Deep Drawing at Elevated Temperatures

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Winklhofer, Johannes; Trattnig, Gernot; Lind, Christoph

    Lightweight design is essential for an economic and environmentally friendly vehicle. Aluminium sheet metal is well known for its ability to improve the strength to weight ratio of lightweight structures. One disadvantage of aluminium is that it is less formable than steel. Therefore complex part geometries can only be realized by expensive multi-step production processes. One method for overcoming this disadvantage is deep drawing at elevated temperatures. In this way the formability of aluminium sheet metal can be improved significantly, and the number of necessary production steps can thereby be reduced. This paper introduces deep drawing of aluminium sheet metalmore » at elevated temperatures, a corresponding simulation method, a characteristic process and its optimization. The temperature and strain rate dependent material properties of a 5xxx series alloy and their modelling are discussed. A three dimensional thermomechanically coupled finite element deep drawing simulation model and its validation are presented. Based on the validated simulation model an optimised process strategy regarding formability, time and cost is introduced.« less

  14. An Approach to Realizing Process Control for Underground Mining Operations of Mobile Machines

    PubMed Central

    Song, Zhen; Schunnesson, Håkan; Rinne, Mikael; Sturgul, John

    2015-01-01

    The excavation and production in underground mines are complicated processes which consist of many different operations. The process of underground mining is considerably constrained by the geometry and geology of the mine. The various mining operations are normally performed in series at each working face. The delay of a single operation will lead to a domino effect, thus delay the starting time for the next process and the completion time of the entire process. This paper presents a new approach to the process control for underground mining operations, e.g. drilling, bolting, mucking. This approach can estimate the working time and its probability for each operation more efficiently and objectively by improving the existing PERT (Program Evaluation and Review Technique) and CPM (Critical Path Method). If the delay of the critical operation (which is on a critical path) inevitably affects the productivity of mined ore, the approach can rapidly assign mucking machines new jobs to increase this amount at a maximum level by using a new mucking algorithm under external constraints. PMID:26062092

  15. An Approach to Realizing Process Control for Underground Mining Operations of Mobile Machines.

    PubMed

    Song, Zhen; Schunnesson, Håkan; Rinne, Mikael; Sturgul, John

    2015-01-01

    The excavation and production in underground mines are complicated processes which consist of many different operations. The process of underground mining is considerably constrained by the geometry and geology of the mine. The various mining operations are normally performed in series at each working face. The delay of a single operation will lead to a domino effect, thus delay the starting time for the next process and the completion time of the entire process. This paper presents a new approach to the process control for underground mining operations, e.g. drilling, bolting, mucking. This approach can estimate the working time and its probability for each operation more efficiently and objectively by improving the existing PERT (Program Evaluation and Review Technique) and CPM (Critical Path Method). If the delay of the critical operation (which is on a critical path) inevitably affects the productivity of mined ore, the approach can rapidly assign mucking machines new jobs to increase this amount at a maximum level by using a new mucking algorithm under external constraints.

  16. Experimental study on the liquefaction of cellulose in supercritical ethanol

    NASA Astrophysics Data System (ADS)

    Peng, Jinxing; Liu, Xinyuan; Bao, Zhenbo

    2018-03-01

    Cellulose is the major composition of solid waste for producing biofuel; cellulose liquefaction is helpful for realizing biomass supercritical liquefaction process. This paper is taking supercritical ethanol as the medium, liquefied cellulose with the intermittence installation of high press cauldron. Experiments have studied technical condition and the technology parameter of cellulose liquefaction in supercritical ethanol, and the pyrolysis mechanism was analysed based on the pyrolysis product. Results show that cellulose can be liquefied, can get good effect through appropriate technology condition. Under not catalyst, highest liquefaction rate of cellulose can reach 73.5%. The composition of the pyrolysis product was determined by GC-MS.

  17. Increase in competitiveness of housing-and-communal services

    NASA Astrophysics Data System (ADS)

    Skripnik, Oksana

    2017-10-01

    The problems, interfering effective activity of housing-and-communal complex are considered in the article. Some factors of the increase in competitiveness and the importance of transactional expenses are revealed. The assessment of competitiveness of the organizations of the sphere of housing-and-communal services is considered as the set of the following basic elements organizational and administrative, marketing, financial, production, indicators of quality, indicators of development, labor indicators interconnected with processes of the organization. The author proves that the increase in competitiveness is possible by carrying out organizational and administrative, innovative, technological, economic transformations, increasing quality of services, reducing costs for production and realization of services, providing new services.

  18. Laser penetration spike welding: a welding tool enabling novel process and design opportunities

    NASA Astrophysics Data System (ADS)

    Dijken, Durandus K.; Hoving, Willem; De Hosson, J. Th. M.

    2002-06-01

    A novel method for laser welding for sheet metal. is presented. This laser spike welding method is capable of bridging large gaps between sheet metal plates. Novel constructions can be designed and manufactured. Examples are light weight metal epoxy multi-layers and constructions having additional strength with respect to rigidity and impact resistance. Its capability to bridge large gaps allows higher dimensional tolerances in production. The required laser systems are commercially available and are easily implemented in existing production lines. The lasers are highly reliable, the resulting spike welds are quickly realized and the cost price per weld is very low.

  19. Innovation-Prototype. Making hydraulic and/or pneumatic plates using 3D printing technology

    NASA Astrophysics Data System (ADS)

    Alexa, V.; Rațiu, S. A.; Kiss, I.; Cioată, V. G.; Rackov, M.

    2018-01-01

    Start 3D printing allows hydraulic and/or pneumatic plates to be obtained from a single technological process without requiring further post-production operations. 3D printing with innovative materials in a rich colour range has several advantages such as: time-saving, cost is the same for any type of plate and its reported just to volume, fast and impossible realization of hydraulic and/or pneumatic links compared to traditional and high accuracy technologies.

  20. Development and Implementation of Production Area of Agricultural Product Data Collection System Based on Embedded System

    NASA Astrophysics Data System (ADS)

    Xi, Lei; Guo, Wei; Che, Yinchao; Zhang, Hao; Wang, Qiang; Ma, Xinming

    To solve problems in detecting the origin of agricultural products, this paper brings about an embedded data-based terminal, applies middleware thinking, and provides reusable long-range two-way data exchange module between business equipment and data acquisition systems. The system is constructed by data collection node and data center nodes. Data collection nodes taking embedded data terminal NetBoxII as the core, consisting of data acquisition interface layer, controlling information layer and data exchange layer, completing the data reading of different front-end acquisition equipments, and packing the data TCP to realize the data exchange between data center nodes according to the physical link (GPRS / CDMA / Ethernet). Data center node consists of the data exchange layer, the data persistence layer, and the business interface layer, which make the data collecting durable, and provide standardized data for business systems based on mapping relationship of collected data and business data. Relying on public communications networks, application of the system could establish the road of flow of information between the scene of origin certification and management center, and could realize the real-time collection, storage and processing between data of origin certification scene and databases of certification organization, and could achieve needs of long-range detection of agricultural origin.

  1. Solving a layout design problem by analytic hierarchy process (AHP) and data envelopment analysis (DEA) approach

    NASA Astrophysics Data System (ADS)

    Tuzkaya, Umut R.; Eser, Arzum; Argon, Goner

    2004-02-01

    Today, growing amounts of waste due to fast consumption rate of products started an irreversible environmental pollution and damage. A considerable part of this waste is caused by packaging material. With the realization of this fact, various waste policies have taken important steps. Here we considered a firm, where waste Aluminum constitutes majority of raw materials for this fir0m. In order to achieve a profitable recycling process, plant layout should be well designed. In this study, we propose a two-step approach involving Analytic Hierarchy Process (AHP) and Data Envelopment Analysis (DEA) to solve facility layout design problems. A case example is considered to demonstrate the results achieved.

  2. Unlocking the potential of supported liquid phase catalysts with supercritical fluids: low temperature continuous flow catalysis with integrated product separation

    PubMed Central

    Franciò, Giancarlo; Hintermair, Ulrich; Leitner, Walter

    2015-01-01

    Solution-phase catalysis using molecular transition metal complexes is an extremely powerful tool for chemical synthesis and a key technology for sustainable manufacturing. However, as the reaction complexity and thermal sensitivity of the catalytic system increase, engineering challenges associated with product separation and catalyst recovery can override the value of the product. This persistent downstream issue often renders industrial exploitation of homogeneous catalysis uneconomical despite impressive batch performance of the catalyst. In this regard, continuous-flow systems that allow steady-state homogeneous turnover in a stationary liquid phase while at the same time effecting integrated product separation at mild process temperatures represent a particularly attractive scenario. While continuous-flow processing is a standard procedure for large volume manufacturing, capitalizing on its potential in the realm of the molecular complexity of organic synthesis is still an emerging area that requires innovative solutions. Here we highlight some recent developments which have succeeded in realizing such systems by the combination of near- and supercritical fluids with homogeneous catalysts in supported liquid phases. The cases discussed exemplify how all three levels of continuous-flow homogeneous catalysis (catalyst system, separation strategy, process scheme) must be matched to locate viable process conditions. PMID:26574523

  3. Unlocking the potential of supported liquid phase catalysts with supercritical fluids: low temperature continuous flow catalysis with integrated product separation.

    PubMed

    Franciò, Giancarlo; Hintermair, Ulrich; Leitner, Walter

    2015-12-28

    Solution-phase catalysis using molecular transition metal complexes is an extremely powerful tool for chemical synthesis and a key technology for sustainable manufacturing. However, as the reaction complexity and thermal sensitivity of the catalytic system increase, engineering challenges associated with product separation and catalyst recovery can override the value of the product. This persistent downstream issue often renders industrial exploitation of homogeneous catalysis uneconomical despite impressive batch performance of the catalyst. In this regard, continuous-flow systems that allow steady-state homogeneous turnover in a stationary liquid phase while at the same time effecting integrated product separation at mild process temperatures represent a particularly attractive scenario. While continuous-flow processing is a standard procedure for large volume manufacturing, capitalizing on its potential in the realm of the molecular complexity of organic synthesis is still an emerging area that requires innovative solutions. Here we highlight some recent developments which have succeeded in realizing such systems by the combination of near- and supercritical fluids with homogeneous catalysts in supported liquid phases. The cases discussed exemplify how all three levels of continuous-flow homogeneous catalysis (catalyst system, separation strategy, process scheme) must be matched to locate viable process conditions. © 2015 The Authors.

  4. The direct aromatization of methane

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Marcelin, G.; Oukaci, R.; Migone, R.A.

    1995-12-31

    The thermal decomposition of methane shows significant potential as a process for the production of higher unsaturated and aromatic hydrocarbons when the extent of the reaction is limited. Thermodynamic calculations have shown that when the reaction is limited to the formation of C{sub 2} to C{sub 10} products, yields of aromatics can exceed 40% at temperatures of 1200{degrees}C. Preliminary experiments have shown that when the reaction is limited to the formation of C{sub 2} to C{sub 10} products, yields of aromatics can exceed 40% at temperatures of 1200{degrees}C. Preliminary experiments have shown that cooling the product and reacting gases asmore » the reaction proceeds can significantly reduce or eliminate the formation of solid carbon and heavier (C{sub 10+}) materials. Much work remains to be done in optimizing the quenching process and this is one of the goals of this program. Means to lower the temperature of the reaction are being studied as this result in a more feasible commercial process due to savings realized in energy and material of construction costs. The use of free-radical generators and catalysts will be investigated as a means of lowering the reaction temperature thus allowing faster quenching. It is highly likely that such studies will lead to a successful direct methane to higher hydrocarbon process.« less

  5. Nutrient controls on new production in the Bodega Bay, California, coastal upwelling plume

    NASA Astrophysics Data System (ADS)

    Dugdale, R. C.; Wilkerson, F. P.; Hogue, V. E.; Marchi, A.

    2006-12-01

    A theoretical framework for the time-dependent processes leading to the high rates of new production in eastern boundary upwelling systems has been assembled from a series of past upwelling studies. As part of the CoOP WEST (Wind Events and Shelf Transport) study, new production in the Bodega Bay upwelling area and it's control by ambient nitrate and ammonium concentrations and the advective wind regime are described. Data and analyses are focused primarily on the WEST 2001 cruise (May-June 2001) when the two legs differed greatly in wind regimes but not nutrient concentrations. Elevated concentrations of ammonium in upwelled water with high nitrate were observed in both legs. Nitrate uptake by phytoplankton as a function of nitrate concentration was linear rather than Michaelis-Menten-like, modulated by inhibitory levels of ammonium, yielding coefficients that enable the specific nitrate uptake element of new production to be estimated from nutrient concentrations. The range of specific nitrate uptake rates for the two legs of WEST 2001 were similar, essentially a physiological response to nutrient conditions. However, the low "realization" of new production i.e. incorporation of biomass as particulate nitrogen that occurred in this system compared to the theoretical maximum possible was determined by the strong advective and turbulent conditions that dominated the second leg of the WEST 2001 study. These data are compared with other upwelling areas using a physiological shift-up model [Dugdale, R.C., Wilkerson, F.P., Morel, A. 1990. Realization of new production in coastal upwelling areas: a means to compare relative performance. Limnology and Oceanography 35, 822-829].

  6. AOD furnace splash soft-sensor in the smelting process based on improved BP neural network

    NASA Astrophysics Data System (ADS)

    Ma, Haitao; Wang, Shanshan; Wu, Libin; Yu, Ying

    2017-11-01

    In view of argon oxygen refining low carbon ferrochrome production process, in the splash of smelting process as the research object, based on splash mechanism analysis in the smelting process , using multi-sensor information fusion and BP neural network modeling techniques is proposed in this paper, using the vibration signal, the audio signal and the flame image signal in the furnace as the characteristic signal of splash, the vibration signal, the audio signal and the flame image signal in the furnace integration and modeling, and reconstruct splash signal, realize the splash soft measurement in the smelting process, the simulation results show that the method can accurately forecast splash type in the smelting process, provide a new method of measurement for forecast splash in the smelting process, provide more accurate information to control splash.

  7. Novel strategy for phenyllactic acid biosynthesis from phenylalanine by whole cell recombinant Escherichia coli coexpressing L-phenylalanine oxidase and L-lactate dehydrogenase.

    PubMed

    Zhang, Jianzhi; Li, Xi

    2018-01-01

    To enhance the efficiency of phenyllactic acid (PLA) production from L-phenylalanine (L-Phe) by introducing a novel artificial pathway into Escherichia coli RESULTS: The production of PLA from L-Phe by recombinant E. coli (ldh-lpox) coexpressing L-phenylalanine oxidase and L-lactate dehydrogenase was studied. The new PLA synthesis pathway was confirmed to be efficient in recombinant E. coli. Subsequently, two different biocatalyst processes were carried out and optimized for PLA production. In the whole cell biosynthesis process at high cell density using collected recombinant cells as catalyst, at optimal conditions (L-Phe 6 g/l, pH 7.5, 35 °C, CDW 24.5 g/l and 200 rpm), the recombinant E. coli (ldh-lpox) produced 1.62 g PLA/l with a conversion of 28% from L-Phe. Similarly, during the two-temperature-stage fermentation process in flasks using IPTG-induced cells, the temperature in the second stage was increased to 35 °C to benefit the biocatalyst process, and comparable phenyllactic acid production of 1.47 g/l was obtained from 12 g L-Phe/l. Recombinant E. coli (ldh-lpox) was efficient in PLA production realizing a high titer of several folds compared with studies using L-Phe as substrate.

  8. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tan, Eric C. D.; Talmadge, Michael; Dutta, Abhijit

    This report was developed as part of the U.S. Department of Energy’s Bioenergy Technologies Office’s (BETO’s) efforts to enable the development of technologies for the production of infrastructure-compatible, cost-competitive liquid hydrocarbon fuels from lignocellulosic biomass feedstocks. The research funded by BETO is designed to advance the state of technology of biomass feedstock supply and logistics, conversion, and overall system sustainability. It is expected that these research improvements will be made within the 2022 timeframe. As part of their involvement in this research and development effort, the National Renewable Energy Laboratory and the Pacific Northwest National Laboratory investigate the economics ofmore » conversion pathways through the development of conceptual biorefinery process models and techno-economic analysis models. This report describes in detail one potential conversion process for the production of high-octane gasoline blendstock via indirect liquefaction of biomass. The processing steps of this pathway include the conversion of biomass to synthesis gas or syngas via indirect gasification, gas cleanup, catalytic conversion of syngas to methanol intermediate, methanol dehydration to dimethyl ether (DME), and catalytic conversion of DME to high-octane, gasoline-range hydrocarbon blendstock product. The conversion process configuration leverages technologies previously advanced by research funded by BETO and demonstrated in 2012 with the production of mixed alcohols from biomass. Biomass-derived syngas cleanup via reforming of tars and other hydrocarbons is one of the key technology advancements realized as part of this prior research and 2012 demonstrations. The process described in this report evaluates a new technology area for the downstream utilization of clean biomass-derived syngas for the production of high-octane hydrocarbon products through methanol and DME intermediates. In this process, methanol undergoes dehydration to DME, which is subsequently converted via homologation reactions to high-octane, gasoline-range hydrocarbon products.« less

  9. Wavelet transform based on inner product in fault diagnosis of rotating machinery: A review

    NASA Astrophysics Data System (ADS)

    Chen, Jinglong; Li, Zipeng; Pan, Jun; Chen, Gaige; Zi, Yanyang; Yuan, Jing; Chen, Binqiang; He, Zhengjia

    2016-03-01

    As a significant role in industrial equipment, rotating machinery fault diagnosis (RMFD) always draws lots of attention for guaranteeing product quality and improving economic benefit. But non-stationary vibration signal with a large amount of noise on abnormal condition of weak fault or compound fault in many cases would lead to this task challenging. As one of the most powerful non-stationary signal processing techniques, wavelet transform (WT) has been extensively studied and widely applied in RMFD. Numerous publications about the study and applications of WT for RMFD have been presented to academic journals, technical reports and conference proceedings. Many previous publications admit that WT can be realized by means of inner product principle of signal and wavelet base. This paper verifies the essence on inner product operation of WT by simulation and field experiments. Then the development process of WT based on inner product is concluded and the applications of major developments in RMFD are also summarized. Finally, super wavelet transform as an important prospect of WT based on inner product are presented and discussed. It is expected that this paper can offer an in-depth and comprehensive references for researchers and help them with finding out further research topics.

  10. Research and Application of Autodesk Fusion360 in Industrial Design

    NASA Astrophysics Data System (ADS)

    Song, P. P.; Qi, Y. M.; Cai, D. C.

    2018-05-01

    In 2016, Fusion 360, a productintroduced byAutodesk and integrating industrial design, structural design, mechanical simulation, and CAM, turns out a design platform supportingcollaboration and sharing both cross-platform and via the cloud. In previous products, design and manufacturing use to be isolated. In the course of design, research and development, the communication between designers and engineers used to go on through different software products, tool commands, and even industry terms. Moreover, difficulty also lies with the communication between design thoughts and machining strategies. Naturally, a difficult product design and R & D process would trigger a noticeable gap between the design model and the actual product. A complete product development process tends to cover several major areas, such as industrial design, mechanical design, rendering and animation, computer aided emulation (CAE), and computer aided manufacturing (CAM). Fusion 360, a perfect design solving the technical problems of cross-platform data exchange, realizes the effective control of cross-regional collaboration and presents an overview of collaboration and breaks the barriers between art and manufacturing, andblocks between design and processing. The “Eco-development of Fusion360 Industrial Chain” is both a significant means to and an inevitable trend forthe manufacturers and industrial designers to carry out innovation in China.

  11. Realization of Quasi‐Omnidirectional Solar Cells with Superior Electrical Performance by All‐Solution‐Processed Si Nanopyramids

    PubMed Central

    Zhong, Sihua; Wang, Wenjie; Tan, Miao; Zhuang, Yufeng

    2017-01-01

    Abstract Large‐scale (156 mm × 156 mm) quasi‐omnidirectional solar cells are successfully realized and featured by keeping high cell performance over broad incident angles (θ), via employing Si nanopyramids (SiNPs) as surface texture. SiNPs are produced by the proposed metal‐assisted alkaline etching method, which is an all‐solution‐processed method and highly simple together with cost‐effective. Interestingly, compared to the conventional Si micropyramids (SiMPs)‐textured solar cells, the SiNPs‐textured solar cells possess lower carrier recombination and thus superior electrical performances, showing notable distinctions from other Si nanostructures‐textured solar cells. Furthermore, SiNPs‐textured solar cells have very little drop of quantum efficiency with increasing θ, demonstrating the quasi‐omnidirectional characteristic. As an overall result, both the SiNPs‐textured homojunction and heterojunction solar cells possess higher daily electric energy production with a maximum relative enhancement approaching 2.5%, when compared to their SiMPs‐textured counterparts. The quasi‐omnidirectional solar cell opens a new opportunity for photovoltaics to produce more electric energy with a low cost. PMID:29201616

  12. Realization of Quasi-Omnidirectional Solar Cells with Superior Electrical Performance by All-Solution-Processed Si Nanopyramids.

    PubMed

    Zhong, Sihua; Wang, Wenjie; Tan, Miao; Zhuang, Yufeng; Shen, Wenzhong

    2017-11-01

    Large-scale (156 mm × 156 mm) quasi-omnidirectional solar cells are successfully realized and featured by keeping high cell performance over broad incident angles (θ), via employing Si nanopyramids (SiNPs) as surface texture. SiNPs are produced by the proposed metal-assisted alkaline etching method, which is an all-solution-processed method and highly simple together with cost-effective. Interestingly, compared to the conventional Si micropyramids (SiMPs)-textured solar cells, the SiNPs-textured solar cells possess lower carrier recombination and thus superior electrical performances, showing notable distinctions from other Si nanostructures-textured solar cells. Furthermore, SiNPs-textured solar cells have very little drop of quantum efficiency with increasing θ, demonstrating the quasi-omnidirectional characteristic. As an overall result, both the SiNPs-textured homojunction and heterojunction solar cells possess higher daily electric energy production with a maximum relative enhancement approaching 2.5%, when compared to their SiMPs-textured counterparts. The quasi-omnidirectional solar cell opens a new opportunity for photovoltaics to produce more electric energy with a low cost.

  13. Process performance and product quality in an integrated continuous antibody production process.

    PubMed

    Karst, Daniel J; Steinebach, Fabian; Soos, Miroslav; Morbidelli, Massimo

    2017-02-01

    Continuous manufacturing is currently being seriously considered in the biopharmaceutical industry as the possible new paradigm for producing therapeutic proteins, due to production cost and product quality related benefits. In this study, a monoclonal antibody producing CHO cell line was cultured in perfusion mode and connected to a continuous affinity capture step. The reliable and stable integration of the two systems was enabled by suitable control loops, regulating the continuous volumetric flow and adapting the operating conditions of the capture process. For the latter, an at-line HPLC measurement of the harvest concentration subsequent to the bioreactor was combined with a mechanistic model of the capture chromatographic unit. Thereby, optimal buffer consumption and productivity throughout the process was realized while always maintaining a yield above the target value of 99%. Stable operation was achieved at three consecutive viable cell density set points (20, 60, and 40 × 10 6 cells/mL), together with consistent product quality in terms of aggregates, fragments, charge isoforms, and N-linked glycosylation. In addition, different values for these product quality attributes such as N-linked glycosylation, charge variants, and aggregate content were measured at the different steady states. As expected, the amount of released DNA and HCP was significantly reduced by the capture step for all considered upstream operating conditions. This study is exemplary for the potential of enhancing product quality control and modulation by integrated continuous manufacturing. Biotechnol. Bioeng. 2017;114: 298-307. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  14. Engineered catalytic biofilms for continuous large scale production of n-octanol and (S)-styrene oxide.

    PubMed

    Gross, Rainer; Buehler, Katja; Schmid, Andreas

    2013-02-01

    This study evaluates the technical feasibility of biofilm-based biotransformations at an industrial scale by theoretically designing a process employing membrane fiber modules as being used in the chemical industry and compares the respective process parameters to classical stirred-tank studies. To our knowledge, catalytic biofilm processes for fine chemicals production have so far not been reported on a technical scale. As model reactions, we applied the previously studied asymmetric styrene epoxidation employing Pseudomonas sp. strain VLB120ΔC biofilms and the here-described selective alkane hydroxylation. Using the non-heme iron containing alkane hydroxylase system (AlkBGT) from P. putida Gpo1 in the recombinant P. putida PpS81 pBT10 biofilm, we were able to continuously produce 1-octanol from octane with a maximal productivity of 1.3 g L ⁻¹(aq) day⁻¹ in a single tube micro reactor. For a possible industrial application, a cylindrical membrane fiber module packed with 84,000 polypropylene fibers is proposed. Based on the here presented calculations, 59 membrane fiber modules (of 0.9 m diameter and 2 m length) would be feasible to realize a production process of 1,000 tons/year for styrene oxide. Moreover, the product yield on carbon can at least be doubled and over 400-fold less biomass waste would be generated compared to classical stirred-tank reactor processes. For the octanol process, instead, further intensification in biological activity and/or surface membrane enlargement is required to reach production scale. By taking into consideration challenges such as biomass growth control and maintaining a constant biological activity, this study shows that a biofilm process at an industrial scale for the production of fine chemicals is a sustainable alternative in terms of product yield and biomass waste production. Copyright © 2012 Wiley Periodicals, Inc.

  15. Comparative study on the conventional and non thermal simultaneous saccharification and fermentation of Manihot glaziovii root starch

    NASA Astrophysics Data System (ADS)

    Hargono, Kumoro, Andri Cahyo; Jos, Bakti

    2015-12-01

    Inconventional ethanol production process, starch is converted into dextrins via liquefaction using α-amylase enzyme at high temperature (90-120°C). Then, dextrins are saccharified by glucoamylase to obtain to monomeric sugars (glucose). Recently, a granular starch hydrolyzing enzymes (GSHE), Stargen 002, was developed to convert starch into dextrins at low temperature (< 32°C) and hydrolyzes dextrins into glucose. The subject of this research was to compare ethanol production using a granular starch hydrolyzing enzymes and conventional enzymatic liquefaction and saccharification in cassava starch processing. Starch slurry concentrations were 20% w/v, and dosage of enzymes 0.50, 1.0 and 2%, respectively, were studied. After 48 hr process the final ethanol concentration for the respective enzyme concentration for conventional process were 34.90, 36.16 and 42.10 g/L, whereas for the non-thermal treatment, final ethanol concentration were 46.4, 57.62 and 59.65 g/L, respectively. By implementation of this non thermal process, the use of energy can be saved by carrying out saccharification step at lower temperature (30°C) could be realized.

  16. Revisiting classical design in engineering from a perspective of frugality.

    PubMed

    Rao, Balkrishna C

    2017-05-01

    The conservative nature of design in engineering has typically unleashed products fabricated with generous amounts of raw materials. This is epitomized by the factor of safety whose values higher than unity suggests various uncertainties of design that are tackled through material padding. This effort proposes a new factor of safety called the factor of frugality that could be used in ecodesign and which addresses both rigors of the classical design process and quantification of savings in materials going into a product. An example of frugal shaft design together with some other cases has been presented to explain the working of the factor of frugality . Adoption of the frugality factor would entail a change in design philosophy whereby designers would constantly make avail of a rigorous design process coupled with material-saving schemes for realizing products that are benign to the environment. Such a change in the foundations of design would abet the stewardship of earth in avoiding planetary boundaries since engineering influences a significant proportion of human endeavors.

  17. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Nigg, D.W.; Mitchell, H.E.; Harker, Y.D.

    Therapeutically-useful epithermal-neutron beams for BNCT are currently generated by nuclear reactors. Various accelerator-based neutron sources for BNCT have been proposed and some low intensity prototypes of such sources, generally featuring the use of proton beams and beryllium or lithium targets have been constructed. This paper describes an alternate approach to the realization of a clinically useful accelerator-based source of epithermal neutrons for BNCT that reconciles the often conflicting objectives of target cooling, neutron beam intensity, and neutron beam spectral purity via a two stage photoneutron production process.

  18. Soil recycling paves the way for treating brownfields

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gladdys, R.

    A soil recycling and stabilization process allows once-contaminated soil to be incorporated into paving materials. Contaminated soils is more widespread than often realized, with one of the more common sources being petroleum products such as fuel oil and gasoline. Until recently, the conventional solution was to have the material excavated, separated from remining soil and trucked to a hazardous waste landfill. This article describes an alternative approach under the following topics: move the solution, not the problem; on site recycling; heavy metals stabilization; economics.

  19. An Integrated Nursing Management Information System: From Concept to Reality

    PubMed Central

    Pinkley, Connie L.; Sommer, Patricia K.

    1988-01-01

    This paper addresses the transition from the conceptualization of a Nursing Management Information System (NMIS) integrated and interdependent with the Hospital Information System (HIS) to its realization. Concepts of input, throughout, and output are presented to illustrate developmental strategies used to achieve nursing information products. Essential processing capabilities include: 1) ability to interact with multiple data sources; 2) database management, statistical, and graphics software packages; 3) online, batch and reporting; and 4) interactive data analysis. Challenges encountered in system construction are examined.

  20. Unification and Enhancement of Planetary Robotic Vision Ground Processing: The EC FP7 Project PRoVisG

    NASA Astrophysics Data System (ADS)

    Paar, G.

    2009-04-01

    At present, mainly the US have realized planetary space missions with essential robotics background. Joining institutions, companies and universities from different established groups in Europe and two relevant players from the US, the EC FP7 Project PRoVisG started in autumn 2008 to demonstrate the European ability of realizing high-level processing of robotic vision image products from the surface of planetary bodies. PRoVisG will build a unified European framework for Robotic Vision Ground Processing. State-of-art computer vision technology will be collected inside and outside Europe to better exploit the image data gathered during past, present and future robotic space missions to the Moon and the Planets. This will lead to a significant enhancement of the scientific, technologic and educational outcome of such missions. We report on the main PRoVisG objectives and the development status: - Past, present and future planetary robotic mission profiles are analysed in terms of existing solutions and requirements for vision processing - The generic processing chain is based on unified vision sensor descriptions and processing interfaces. Processing components available at the PRoVisG Consortium Partners will be completed by and combined with modules collected within the international computer vision community in the form of Announcements of Opportunity (AOs). - A Web GIS is developed to integrate the processing results obtained with data from planetary surfaces into the global planetary context. - Towards the end of the 39 month project period, PRoVisG will address the public by means of a final robotic field test in representative terrain. The European tax payers will be able to monitor the imaging and vision processing in a Mars - similar environment, thus getting an insight into the complexity and methods of processing, the potential and decision making of scientific exploitation of such data and not least the elegancy and beauty of the resulting image products and their visualization. - The educational aspect is addressed by two summer schools towards the end of the project, presenting robotic vision to the students who are future providers of European science and technology, inside and outside the space domain.

  1. Multivariate constrained shape optimization: Application to extrusion bell shape for pasta production

    NASA Astrophysics Data System (ADS)

    Sarghini, Fabrizio; De Vivo, Angela; Marra, Francesco

    2017-10-01

    Computational science and engineering methods have allowed a major change in the way products and processes are designed, as validated virtual models - capable to simulate physical, chemical and bio changes occurring during production processes - can be realized and used in place of real prototypes and performing experiments, often time and money consuming. Among such techniques, Optimal Shape Design (OSD) (Mohammadi & Pironneau, 2004) represents an interesting approach. While most classical numerical simulations consider fixed geometrical configurations, in OSD a certain number of geometrical degrees of freedom is considered as a part of the unknowns: this implies that the geometry is not completely defined, but part of it is allowed to move dynamically in order to minimize or maximize the objective function. The applications of optimal shape design (OSD) are uncountable. For systems governed by partial differential equations, they range from structure mechanics to electromagnetism and fluid mechanics or to a combination of the three. This paper presents one of possible applications of OSD, particularly how extrusion bell shape, for past production, can be designed by applying a multivariate constrained shape optimization.

  2. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rittmann, Bruce; Krajmalnik‐Brown, Rosa; Zevin, Alexander

    The grandest challenge facing human society today is providing large amounts of energy and industrial chemicals that are renewable and carbon-neutral. An outstanding opportunity lies in employing photosynthetic microorganisms, which have the potential to generate energy and chemical feedstock from sunlight and CO 2 at rates 10 to 100 times greater than plants. Major challenges for solar-powered production using photosynthetic microorganisms are associated with the harvesting and downstream processing of biomass to yield the usable energy or material feedstock e.g. The technical challenges and costs of downstream processing could be avoided if, powered by solar energy, the photosynthetic microorganisms weremore » to convert CO 2 directly to the desired product, which they release for direct harvesting. This approach creates a true photosynthetic factory, our goal for Photosynthetic Factory Direct! Our team is able to genetically modify the cyanobacterium Synechocystis sp. PCC 6803 so that it produces and excretes a range of renewable energy and chemical products directly from CO 2 and sunlight. Essential to realizing the potential of the photosynthetic factory is an engineered Advanced Photobioreactor (APBR) for reliable synthesis and harvest of the products.« less

  3. The photoirradiation induced p-n junction in naphthylamine-based organic photovoltaic cells

    NASA Astrophysics Data System (ADS)

    Bai, Linyi; Gao, Qiang; Xia, Youyi; Ang, Chung Yen; Bose, Purnandhu; Tan, Si Yu; Zhao, Yanli

    2015-08-01

    The bulk heterojunction (BHJ) plays an indispensable role in organic photovoltaics, and thus has been investigated extensively in recent years. While a p-n heterojunction is usually fabricated using two different donor and acceptor materials such as poly(3-hexylthiophene-2,5-diyl) (P3HT) and phenyl-C61-butyric acid methyl ester (PCBM), it is really rare that such a BHJ is constructed by a single entity. Here, we presented a photoirradiation-induced p-n heterojunction in naphthylamine-based organic photovoltaic cells, where naphthylamine as a typical p-type semiconductor could be oxidized under photoirradiation and transformed into a new semiconductor with the n-type character. The p-n heterojunction was realized using both the remaining naphthylamine and its oxidative product, giving rise to the performance improvement in organic photovoltaic devices. The experimental results show that the power conversion efficiency (PCE) of the devices could be achieved up to 1.79% and 0.43% in solution and thin film processes, respectively. Importantly, this technology using naphthylamine does not require classic P3HT and PCBM to realize the p-n heterojunction, thereby simplifying the device fabrication process. The present approach opens up a promising route for the development of novel materials applicable to the p-n heterojunction.The bulk heterojunction (BHJ) plays an indispensable role in organic photovoltaics, and thus has been investigated extensively in recent years. While a p-n heterojunction is usually fabricated using two different donor and acceptor materials such as poly(3-hexylthiophene-2,5-diyl) (P3HT) and phenyl-C61-butyric acid methyl ester (PCBM), it is really rare that such a BHJ is constructed by a single entity. Here, we presented a photoirradiation-induced p-n heterojunction in naphthylamine-based organic photovoltaic cells, where naphthylamine as a typical p-type semiconductor could be oxidized under photoirradiation and transformed into a new semiconductor with the n-type character. The p-n heterojunction was realized using both the remaining naphthylamine and its oxidative product, giving rise to the performance improvement in organic photovoltaic devices. The experimental results show that the power conversion efficiency (PCE) of the devices could be achieved up to 1.79% and 0.43% in solution and thin film processes, respectively. Importantly, this technology using naphthylamine does not require classic P3HT and PCBM to realize the p-n heterojunction, thereby simplifying the device fabrication process. The present approach opens up a promising route for the development of novel materials applicable to the p-n heterojunction. Electronic supplementary information (ESI) available: Additional synthesis and characterization details. See DOI: 10.1039/c5nr04471e

  4. Design and development of a layer-based additive manufacturing process for the realization of metal parts of designed mesostructure

    NASA Astrophysics Data System (ADS)

    Williams, Christopher Bryant

    Low-density cellular materials, metallic bodies with gaseous voids, are a unique class of materials that are characterized by their high strength, low mass, good energy absorption characteristics, and good thermal and acoustic insulation properties. In an effort to take advantage of this entire suite of positive mechanical traits, designers are tailoring the cellular mesostructure for multiple design objectives. Unfortunately, existing cellular material manufacturing technologies limit the design space as they are limited to certain part mesostructure, material type, and macrostructure. The opportunity that exists to improve the design of existing products, and the ability to reap the benefits of cellular materials in new applications is the driving force behind this research. As such, the primary research goal of this work is to design, embody, and analyze a manufacturing process that provides a designer the ability to specify the material type, material composition, void morphology, and mesostructure topology for any conceivable part geometry. The accomplishment of this goal is achieved in three phases of research: (1) Design---Following a systematic design process and a rigorous selection exercise, a layer-based additive manufacturing process is designed that is capable of meeting the unique requirements of fabricating cellular material geometry. Specifically, metal parts of designed mesostructure are fabricated via three-dimensional printing of metal oxide ceramic powder followed by post-processing in a reducing atmosphere. (2) Embodiment ---The primary research hypothesis is verified through the use of the designed manufacturing process chain to successfully realize metal parts of designed mesostructure. (3) Modeling & Evaluation ---The designed manufacturing process is modeled in this final research phase so as to increase understanding of experimental results and to establish a foundation for future analytical modeling research. In addition to an analysis of the physics of primitive creation and an investigation of failure modes during the layered fabrication of thin trusses, build time and cost models are presented in order to verify claims of the process's economic benefits. The main contribution of this research is the embodiment of a novel manner for realizing metal parts of designed mesostructure.

  5. New ways to develop biosensors towards addressing practical problems

    NASA Astrophysics Data System (ADS)

    Starodub, N. F.

    2013-11-01

    The main modern approaches which were realized at the development of new generation of biosensors intended for application in field of diagnostics, food quality control and environmental monitoring are presented. The main attention was paid to creation of the multi-parametrical and multi-functional enzymatic and immune biosensors which were realized for the complex diagnostics of diabetes, autoimmune state and for the control of process of sugar production. The label-free bioaffine devices based on the nano-porouse silicon (NPS) with the registration of specific formed signal by chemiluminescence (ChL) and photoresistivity and intended for the determination mycotoxins and diagnostics of retroviral bovine leukemia (RBL) are analyzed too. Improving of ion sensitive field effect transistors (ISFETs) through changing silicon nitride on the cerium oxide is discussed as perspective approach in case of micotoxins and Salmonella control. In the conclusion the possibility to replace biological sensitive elements by artificial ones is considered.

  6. Development of on line automatic separation device for apple and sleeve

    NASA Astrophysics Data System (ADS)

    Xin, Dengke; Ning, Duo; Wang, Kangle; Han, Yuhang

    2018-04-01

    Based on STM32F407 single chip microcomputer as control core, automatic separation device of fruit sleeve is designed. This design consists of hardware and software. In hardware, it includes mechanical tooth separator and three degree of freedom manipulator, as well as industrial control computer, image data acquisition card, end effector and other structures. The software system is based on Visual C++ development environment, to achieve localization and recognition of fruit sleeve with the technology of image processing and machine vision, drive manipulator of foam net sets of capture, transfer, the designated position task. Test shows: The automatic separation device of the fruit sleeve has the advantages of quick response speed and high separation success rate, and can realize separation of the apple and plastic foam sleeve, and lays the foundation for further studying and realizing the application of the enterprise production line.

  7. Effects of Activation Energy to Transient Response of Semiconductor Gas Sensor

    NASA Astrophysics Data System (ADS)

    Fujimoto, Akira; Ohtani, Tatsuki

    The smell classifiable gas sensor will be desired for many applications such as gas detection alarms, process controls for food production and so on. We have tried to realize the sensor using transient responses of semiconductor gas sensor consisting of tin dioxide and pointed out that the sensor gave us different transient responses for kinds of gas. Results of model calculation showed the activation energy of chemical reaction on the sensor surface strongly depended on the transient response. We tried to estimate the activation energies by molecular orbital calculation with SnO2 Cluster. The results show that there is a liner relationship between the gradient of the transient responses and activation energies for carboxylic and alcoholic gases. Transient response will be predicted from activation energy in the same kind of gas and the smell discrimination by single semiconductor gas sensor will be realized by this relationship.

  8. Research on crude oil storage and transportation based on optimization algorithm

    NASA Astrophysics Data System (ADS)

    Yuan, Xuhua

    2018-04-01

    At present, the optimization theory and method have been widely used in the optimization scheduling and optimal operation scheme of complex production systems. Based on C++Builder 6 program development platform, the theoretical research results are implemented by computer. The simulation and intelligent decision system of crude oil storage and transportation inventory scheduling are designed. The system includes modules of project management, data management, graphics processing, simulation of oil depot operation scheme. It can realize the optimization of the scheduling scheme of crude oil storage and transportation system. A multi-point temperature measuring system for monitoring the temperature field of floating roof oil storage tank is developed. The results show that by optimizing operating parameters such as tank operating mode and temperature, the total transportation scheduling costs of the storage and transportation system can be reduced by 9.1%. Therefore, this method can realize safe and stable operation of crude oil storage and transportation system.

  9. Study on Full Supply Chain Quality and Safetytraceability Systems For Cereal And Oilproducts

    NASA Astrophysics Data System (ADS)

    Liu, Shihong; Zheng, Huoguo; Meng, Hong; Hu, Haiyan; Wu, Jiangshou; Li, Chunhua

    Global food industry and Governments in many countries are putting increasing emphasis on establishment of food traceability systems. Food traceability has become an effective way in food safety management. Aimed at the major quality problems of cereal and oil products existing in the production, processing, warehousing, distribution and other links in the supply chain, this paper firstly proposes a new traceability framework combines the information flow with critical control points and quality indicators. Then it introduces traceability database design and data access mode to realize the framework. In practice, Code design for tracing goods is a challenge thing, so this paper put forward a code system based on UCC/EAN-128 standard.Middleware and Electronic terminal design are also briefly introduced to accomplish traceability system for cereal and oil products.

  10. The analysis of disperse and elemental composition of dust from drobestry installations of foundry at the production of construction structures for altitude buildings

    NASA Astrophysics Data System (ADS)

    Ivanova, Irina; Golovina, Elena; Kulakov, Kirill; Sorokin, Andrey

    2018-03-01

    In the production of building structures for high-rise buildings, the dangerous and harmful factors of foundry production include high concentrations of dust and harmful gases released at various stages of the process. Disperse and elemental compositions of dust determine the hygienic state of the working area of the foundry. According to experts, the presence of dust of less than 10 microns in size in the air increases the danger of getting occupational diseases, such as pneumoconiosis (silicosis), bronchitis, dermatitis, conjunctivitis. The determination of the granulometric composition of the powder sample provided was carried out by the laser diffraction method realized on a laser particle analyzer Fritsch NanoTec «ANALISETTE 22».

  11. High-accuracy microassembly by intelligent vision systems and smart sensor integration

    NASA Astrophysics Data System (ADS)

    Schilp, Johannes; Harfensteller, Mark; Jacob, Dirk; Schilp, Michael

    2003-10-01

    Innovative production processes and strategies from batch production to high volume scale are playing a decisive role in generating microsystems economically. In particular assembly processes are crucial operations during the production of microsystems. Due to large batch sizes many microsystems can be produced economically by conventional assembly techniques using specialized and highly automated assembly systems. At laboratory stage microsystems are mostly assembled by hand. Between these extremes there is a wide field of small and middle sized batch production wherefore common automated solutions rarely are profitable. For assembly processes at these batch sizes a flexible automated assembly system has been developed at the iwb. It is based on a modular design. Actuators like grippers, dispensers or other process tools can easily be attached due to a special tool changing system. Therefore new joining techniques can easily be implemented. A force-sensor and a vision system are integrated into the tool head. The automated assembly processes are based on different optical sensors and smart actuators like high-accuracy robots or linear-motors. A fiber optic sensor is integrated in the dispensing module to measure contactless the clearance between the dispense needle and the substrate. Robot vision systems using the strategy of optical pattern recognition are also implemented as modules. In combination with relative positioning strategies, an assembly accuracy of the assembly system of less than 3 μm can be realized. A laser system is used for manufacturing processes like soldering.

  12. Design of an automatic production monitoring system on job shop manufacturing

    NASA Astrophysics Data System (ADS)

    Prasetyo, Hoedi; Sugiarto, Yohanes; Rosyidi, Cucuk Nur

    2018-02-01

    Every production process requires monitoring system, so the desired efficiency and productivity can be monitored at any time. This system is also needed in the job shop type of manufacturing which is mainly influenced by the manufacturing lead time. Processing time is one of the factors that affect the manufacturing lead time. In a conventional company, the recording of processing time is done manually by the operator on a sheet of paper. This method is prone to errors. This paper aims to overcome this problem by creating a system which is able to record and monitor the processing time automatically. The solution is realized by utilizing electric current sensor, barcode, RFID, wireless network and windows-based application. An automatic monitoring device is attached to the production machine. It is equipped with a touch screen-LCD so that the operator can use it easily. Operator identity is recorded through RFID which is embedded in his ID card. The workpiece data are collected from the database by scanning the barcode listed on its monitoring sheet. A sensor is mounted on the machine to measure the actual machining time. The system's outputs are actual processing time and machine's capacity information. This system is connected wirelessly to a workshop planning application belongs to the firm. Test results indicated that all functions of the system can run properly. This system successfully enables supervisors, PPIC or higher level management staffs to monitor the processing time quickly with a better accuracy.

  13. Realizing the Living Paper using the ProvONE Model for Reproducible Research

    NASA Astrophysics Data System (ADS)

    Jones, M. B.; Jones, C. S.; Ludäscher, B.; Missier, P.; Walker, L.; Slaughter, P.; Schildhauer, M.; Cuevas-Vicenttín, V.

    2015-12-01

    Science has advanced through traditional publications that codify research results as a permenant part of the scientific record. But because publications are static and atomic, researchers can only cite and reference a whole work when building on prior work of colleagues. The open source software model has demonstrated a new approach in which strong version control in an open environment can nurture an open ecosystem of software. Developers now commonly fork and extend software giving proper credit, with less repetition, and with confidence in the relationship to original software. Through initiatives like 'Beyond the PDF', an analogous model has been imagined for open science, in which software, data, analyses, and derived products become first class objects within a publishing ecosystem that has evolved to be finer-grained and is realized through a web of linked open data. We have prototyped a Living Paper concept by developing the ProvONE provenance model for scientific workflows, with prototype deployments in DataONE. ProvONE promotes transparency and openness by describing the authenticity, origin, structure, and processing history of research artifacts and by detailing the steps in computational workflows that produce derived products. To realize the Living Paper, we decompose scientific papers into their constituent products and publish these as compound objects in the DataONE federation of archival repositories. Each individual finding and sub-product of a reseach project (such as a derived data table, a workflow or script, a figure, an image, or a finding) can be independently stored, versioned, and cited. ProvONE provenance traces link these fine-grained products within and across versions of a paper, and across related papers that extend an original analysis. This allows for open scientific publishing in which researchers extend and modify findings, creating a dynamic, evolving web of results that collectively represent the scientific enterprise. The Living Paper provides detailed metadata for properly interpreting and verifying individual research findings, for tracing the origin of ideas, for launching new lines of inquiry, and for implementing transitive credit for research and engineering.

  14. Bioreactors for high cell density and continuous multi-stage cultivations: options for process intensification in cell culture-based viral vaccine production.

    PubMed

    Tapia, Felipe; Vázquez-Ramírez, Daniel; Genzel, Yvonne; Reichl, Udo

    2016-03-01

    With an increasing demand for efficacious, safe, and affordable vaccines for human and animal use, process intensification in cell culture-based viral vaccine production demands advanced process strategies to overcome the limitations of conventional batch cultivations. However, the use of fed-batch, perfusion, or continuous modes to drive processes at high cell density (HCD) and overextended operating times has so far been little explored in large-scale viral vaccine manufacturing. Also, possible reductions in cell-specific virus yields for HCD cultivations have been reported frequently. Taking into account that vaccine production is one of the most heavily regulated industries in the pharmaceutical sector with tough margins to meet, it is understandable that process intensification is being considered by both academia and industry as a next step toward more efficient viral vaccine production processes only recently. Compared to conventional batch processes, fed-batch and perfusion strategies could result in ten to a hundred times higher product yields. Both cultivation strategies can be implemented to achieve cell concentrations exceeding 10(7) cells/mL or even 10(8) cells/mL, while keeping low levels of metabolites that potentially inhibit cell growth and virus replication. The trend towards HCD processes is supported by development of GMP-compliant cultivation platforms, i.e., acoustic settlers, hollow fiber bioreactors, and hollow fiber-based perfusion systems including tangential flow filtration (TFF) or alternating tangential flow (ATF) technologies. In this review, these process modes are discussed in detail and compared with conventional batch processes based on productivity indicators such as space-time yield, cell concentration, and product titers. In addition, options for the production of viral vaccines in continuous multi-stage bioreactors such as two- and three-stage systems are addressed. While such systems have shown similar virus titers compared to batch cultivations, keeping high yields for extended production times is still a challenge. Overall, we demonstrate that process intensification of cell culture-based viral vaccine production can be realized by the consequent application of fed-batch, perfusion, and continuous systems with a significant increase in productivity. The potential for even further improvements is high, considering recent developments in establishment of new (designer) cell lines, better characterization of host cell metabolism, advances in media design, and the use of mathematical models as a tool for process optimization and control.

  15. White paper on continuous bioprocessing. May 20-21, 2014 Continuous Manufacturing Symposium.

    PubMed

    Konstantinov, Konstantin B; Cooney, Charles L

    2015-03-01

    There is a growing interest in realizing the benefits of continuous processing in biologics manufacturing, which is reflected by the significant number of industrial and academic researchers who are actively involved in the development of continuous bioprocessing systems. These efforts are further encouraged by guidance expressed in recent US FDA conference presentations. The advantages of continuous manufacturing include sustained operation with consistent product quality, reduced equipment size, high-volumetric productivity, streamlined process flow, low-process cycle times, and reduced capital and operating cost. This technology, however, poses challenges, which need to be addressed before routine implementation is considered. This paper, which is based on the available literature and input from a large number of reviewers, is intended to provide a consensus of the opportunities, technical needs, and strategic directions for continuous bioprocessing. The discussion is supported by several examples illustrating various architectures of continuous bioprocessing systems. © 2014 Wiley Periodicals, Inc. and the American Pharmacists Association.

  16. Realization of FRC interior and exterior furniture

    NASA Astrophysics Data System (ADS)

    Šonka, Š.; Frantová, M.; Štemberk, P.; Havrda, J.; Janouch, P.

    2017-09-01

    This article deals with the implementation of fibre reinforced concrete for interior and exterior furniture. The use of fibre reinforced concrete for non-traditional and small structures brings some specifics in design and realization. These are, in particular, the design of a suitable mixture, the choice of the shape of the structure in relation to the technological possibilities of realization, the static effects and finally the actual production of the element.

  17. Fuel Cell Seminar, 1992: Program and abstracts

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1992-12-31

    This year`s theme, ``Fuel Cells: Realizing the Potential,`` focuses on progress being made toward commercial manufacture and use of fuel cell products. Fuel cell power plants are competing for market share in some applications and demonstrations of market entry power plants are proceeding for additional applications. Development activity on fuel cells for transportation is also increasing; fuel cell products have potential in energy and transportation industries, with very favorable environmental impacts. This Seminar has the purpose of fostering communication by providing a forum for the international community interested in development, application, and business opportunities related fuel cells. Over 190 technicalmore » papers are included, the majority being processed for the data base.« less

  18. An Engineering Method of Civil Jet Requirements Validation Based on Requirements Project Principle

    NASA Astrophysics Data System (ADS)

    Wang, Yue; Gao, Dan; Mao, Xuming

    2018-03-01

    A method of requirements validation is developed and defined to meet the needs of civil jet requirements validation in product development. Based on requirements project principle, this method will not affect the conventional design elements, and can effectively connect the requirements with design. It realizes the modern civil jet development concept, which is “requirement is the origin, design is the basis”. So far, the method has been successfully applied in civil jet aircraft development in China. Taking takeoff field length as an example, the validation process and the validation method of the requirements are detailed introduced in the study, with the hope of providing the experiences to other civil jet product design.

  19. Contributions to optimization of storage and transporting industrial goods

    NASA Astrophysics Data System (ADS)

    Babanatsas, T.; Babanatis Merce, R. M.; Glăvan, D. O.; Glăvan, A.

    2018-01-01

    Optimization of storage and transporting industrial goods in a factory either from a constructive, functional, or technological point of view is a determinant parameter in programming the manufacturing process, the performance of the whole process being determined by the correlation realized taking in consideration those two factors (optimization and programming the process). It is imperative to take into consideration each type of production program (range), to restrain as much as possible the area that we are using and to minimize the times of execution, all of these in order to satisfy the client’s needs, to try to classify them in order to be able to define a global software (with general rules) that is expected to fulfil each client’s needs.

  20. Monitoring of Lactobacillus fermentation process by using ion chromatography with a series piezoelectric quartz crystal detector.

    PubMed

    Zhang, J; Xie, Y; Dai, X; Wei, W

    2001-03-01

    A new method monitoring Lactobacillus fermentation process, which combines ion chromatography (IC) with a series piezoelectric quartz crystal (SPQC) technique, is presented in this paper. Monitoring of the fermentation process was realized by examining the rate of production of lactic acid. An automatic membrane dialyser was used for the pretreatment of the sample in on-line monitoring. A mixture of p-hydroxybenzoic acid and N,N-diethylethanolamine was adopted as mobile phase and its flow rate was 0.8 ml/min. The effects of some fermentation conditions were also discussed in detail. Accordingly, the optimal fermentation conditions were obtained. This method is simple and convenient while the results obtained are accurate and reliable.

  1. [City-hospital network and quality control of officinal preparations].

    PubMed

    Curti, C; Gallice, S; Lamy, E; Rathelot, P; Vanelle, P

    2018-05-01

    In a hospital environment, the quality control of the hospital preparations allows to release homogeneous batches in a secure way. These controls are totally integrated into the process of production and can also, in certain cases, be realized for high-alert magistral preparations. In community pharmacy, these controls were not required, but the Agence régionale de santé (ARS) recently incited compounding community pharmacies to realize this type of analyses. This decision motivated the creation of a collaboration between the pharmacy department of a French teaching hospital and a society including around thirty community pharmacies having a preparatory. Twenty community pharmacies distributed on all the territory have submitted one of their pediatric preparation, capsules of captopril 2mg, to the pharmacopoeia controls usually realized in the industry or hospital. All the analyzed batches were in agreement with European Pharmacopeia specifications. We shall present the rational of this work, the results as well as the numerous perspectives offered by this new type of collaboration joining completely the logic of a network city-hospital allowing the improvement of security of the medication circuit in France. Copyright © 2017 Académie Nationale de Pharmacie. Published by Elsevier Masson SAS. All rights reserved.

  2. Fermentation and purification strategies for the production of betulinic acid and its lupane-type precursors in Saccharomyces cerevisiae.

    PubMed

    Czarnotta, Eik; Dianat, Mariam; Korf, Marcel; Granica, Fabian; Merz, Juliane; Maury, Jérôme; Baallal Jacobsen, Simo A; Förster, Jochen; Ebert, Birgitta E; Blank, Lars M

    2017-11-01

    Microbial production of plant derived, biologically active compounds has the potential to provide economic and ecologic alternatives to existing low productive, plant-based processes. Current production of the pharmacologically active cyclic triterpenoid betulinic acid is realized by extraction from the bark of plane tree or birch. Here, we reengineered the reported betulinic acid pathway into Saccharomyces cerevisiae and used this novel strain to develop efficient fermentation and product purification methods. Fed-batch cultivations with ethanol excess, using either an ethanol-pulse feed or controlling a constant ethanol concentration in the fermentation medium, significantly enhanced production of betulinic acid and its triterpenoid precursors. The beneficial effect of excess ethanol was further exploited in nitrogen-limited resting cell fermentations, yielding betulinic acid concentrations of 182 mg/L, and total triterpenoid concentrations of 854 mg/L, the highest concentrations reported so far. Purification of lupane-type triterpenoids with high selectivity and yield was achieved by solid-liquid extraction without prior cell disruption using polar aprotic solvents such as acetone or ethyl acetate and subsequent precipitation with strong acids. This study highlights the potential of microbial production of plant derived triterpenoids in S. cerevisiae by combining metabolic and process engineering. © 2017 Wiley Periodicals, Inc.

  3. Geosensors to Support Crop Production: Current Applications and User Requirements

    PubMed Central

    Thessler, Sirpa; Kooistra, Lammert; Teye, Frederick; Huitu, Hanna; Bregt, Arnold K.

    2011-01-01

    Sensor technology, which benefits from high temporal measuring resolution, real-time data transfer and high spatial resolution of sensor data that shows in-field variations, has the potential to provide added value for crop production. The present paper explores how sensors and sensor networks have been utilised in the crop production process and what their added-value and the main bottlenecks are from the perspective of users. The focus is on sensor based applications and on requirements that users pose for them. Literature and two use cases were reviewed and applications were classified according to the crop production process: sensing of growth conditions, fertilising, irrigation, plant protection, harvesting and fleet control. The potential of sensor technology was widely acknowledged along the crop production chain. Users of the sensors require easy-to-use and reliable applications that are actionable in crop production at reasonable costs. The challenges are to develop sensor technology, data interoperability and management tools as well as data and measurement services in a way that requirements can be met, and potential benefits and added value can be realized in the farms in terms of higher yields, improved quality of yields, decreased input costs and production risks, and less work time and load. PMID:22163978

  4. An international technology platform for influenza vaccines.

    PubMed

    Hendriks, Jan; Holleman, Marit; de Boer, Otto; de Jong, Patrick; Luytjes, Willem

    2011-07-01

    Since 2008, the World Health Organization has provided seed grants to 11 manufacturers in low- and middle-income countries to establish or improve their pandemic influenza vaccine production capacity. To facilitate this ambitious project, an influenza vaccine technology platform (or "hub") was established at the Netherlands Vaccine Institute for training and technology transfer to developing countries. During its first two years of operation, a robust and transferable monovalent pilot process for egg-based inactivated whole virus influenza A vaccine production was established under international Good Manufacturing Practice standards, as well as in-process and release assays. A course curriculum was designed, including a two-volume practical handbook on production and quality control. Four generic hands-on training courses were successfully realized for over 40 employees from 15 developing country manufacturers. Planned extensions to the curriculum include cell-culture based technology for viral vaccine production, split virion influenza production, and generic adjuvant formulation. We conclude that technology transfer through the hub model works well, significantly builds vaccine manufacturing capacity in developing countries, and thereby increases global and equitable access to vaccines of high public health relevance. Copyright © 2011 Elsevier Ltd. All rights reserved.

  5. High productivity mould robotic milling in Al-5083

    NASA Astrophysics Data System (ADS)

    Urresti, Iker; Arrazola, Pedro Jose; Ørskov, Klaus Bonde; Pelegay, Jose Angel

    2018-05-01

    Industrial serial robots were usually limited to welding, handling or spray painting operations until very recent years. However, some industries have already realized about their important capabilities in terms of flexibility, working space, adaptability and cost. Hence, currently they are seriously being considered to carry out certain metal machining tasks. Therefore, robot based machining is presented as a cost-saving and flexible manufacturing alternative compared to conventional CNC machines especially for roughing or even pre-roughing of large parts. Nevertheless, there are still some drawbacks usually referred as low rigidity, accuracy and repeatability. Thus, the process productivity is usually sacrificed getting low Material Removal Rates (MRR), and consequently not being competitive. Nevertheless, in this paper different techniques to obtain increased productivity are presented, though an appropriate selection of cutting strategies and parameters that are essential for it. During this research some rough milling tests in Al-5083 are presented where High Feed Milling (HFM) is implemented as productive cutting strategy and the experimental modal analysis named Tap-testing is used for the suitable choice of cutting conditions. Competitive productivity rates are experienced while process stability is checked through the cutting forces measurements in order to prove the effectiveness of the experimental modal analysis for robotic machining.

  6. DUV-microscope objectives: technology driver that forces the production to switch from the micrometer scale to the nanometer scale

    NASA Astrophysics Data System (ADS)

    Sure, Thomas; Bauer, Tobias; Heil, Joachim; Wesner, Joachim

    2005-10-01

    Cemented doublets and triplets can not be used for objectives working at wavelengths of 248 nm and shorter, because the optical cement can not withstand the high photon energies. It will be shown that high NA deep UV objectives can be designed and built successfully with the help of air spaced doublets. Assuring Strehl ratios above 95% enforces very tight tolerances. For example the distance error of the lens vertex to its mount has to be less than 1 μm. This calls for a new manufacturing precision never realized before in series production. We show how a white light Mirau interferometer can be used to measure lens vertex positions with an accuracy of 200 nm. We also demonstrate how the fine-tuning process can be optimized by using a "simulated star test", where the point-spread function is calculated in real time with a FFT-algorithm from the optical path difference data, acquired by a Twyman-Green interferometer. To realize the required precision, today various measurement techniques and production processes are used. Picking up the subgroups on different machining tools and measurement systems will loosen the accuracy. Here, we present the concept and the layout of a new manufacturing tool where we implemented the different measurement techniques needed in one CNC machining center. This tool is able to 1) adjust automatically the optical axis of the subgroups related to the machining axis better than 0.5 μm with the help of the stick-slip effect where a mechanical impulse is transferred by an electromagnetically driven hammer, 2) measure the lens vertex relative to the shoulder of the mount with an accuracy of 250 nm and 3) do all steps which are necessary to process the lens mount within the accuracies described above.

  7. Understanding the reliability of solder joints used in advanced structural and electronics applications: Part 1 - Filler metal properties and the soldering process

    DOE PAGES

    Vianco, Paul T.

    2017-02-01

    Soldering technology has made tremendous strides in the past half-century. Whether structural or electronic, all solder joints must provide a level of reliability that is required by the application. This Part 1 report examines the effects of filler metal properties and soldering process on joint reliability. Solder alloy composition must have the appropriate melting and mechanical properties that suit the product's assembly process(es) and use environment. The filler metal must also optimize solderability (wetting-and-spreading) to realize the proper joint geometry. Here, the soldering process also affects joint reliability. The choice of flux and thermal profile support the solderability performance ofmore » the molten filler metal to successfully fill the gap and complete the fillet.« less

  8. Problems of systems dataware using optoelectronic measuring means of linear displacement

    NASA Astrophysics Data System (ADS)

    Bazykin, S. N.; Bazykina, N. A.; Samohina, K. S.

    2017-10-01

    Problems of the dataware of the systems with the use of optoelectronic means of the linear displacement are considered in the article. The classification of the known physical effects, realized by the means of information-measuring systems, is given. The organized analysis of information flows in technical systems from the standpoint of determination of inaccuracies of measurement and management was conducted. In spite of achieved successes in automation of machine-building and instruments-building equipment in the field of dataware of the technical systems, there are unresolved problems, concerning the qualitative aspect of the production process. It was shown that the given problem can be solved using optoelectronic lazer information-measuring systems. Such information-measuring systems are capable of not only executing the measuring functions, but also solving the problems of management and control during processing, thereby guaranteeing the quality of final products.

  9. SOM neural network fault diagnosis method of polymerization kettle equipment optimized by improved PSO algorithm.

    PubMed

    Wang, Jie-sheng; Li, Shu-xia; Gao, Jie

    2014-01-01

    For meeting the real-time fault diagnosis and the optimization monitoring requirements of the polymerization kettle in the polyvinyl chloride resin (PVC) production process, a fault diagnosis strategy based on the self-organizing map (SOM) neural network is proposed. Firstly, a mapping between the polymerization process data and the fault pattern is established by analyzing the production technology of polymerization kettle equipment. The particle swarm optimization (PSO) algorithm with a new dynamical adjustment method of inertial weights is adopted to optimize the structural parameters of SOM neural network. The fault pattern classification of the polymerization kettle equipment is to realize the nonlinear mapping from symptom set to fault set according to the given symptom set. Finally, the simulation experiments of fault diagnosis are conducted by combining with the industrial on-site historical data of the polymerization kettle and the simulation results show that the proposed PSO-SOM fault diagnosis strategy is effective.

  10. Pair production in the gravitational field of a cosmic string

    NASA Astrophysics Data System (ADS)

    Harari, Diego D.; Skarzhinsky, Vladimir D.

    1990-04-01

    We show that many elementary particle physics processes, such as pair production by a high energy photon, that take place in Minkowski space only if a non-uniform external field provides for momentum non-conservation, do occur in the space-time around a straight cosmic string, even though the space is locally flat and there is no local gravitational potential. We exemplify this mechanism through the evaluation of the cross section per unit length of string for the decay of a massless scalar particle into a pair of massive particles. The cross sections for this kind of processes are typically small. Nevertheless, it is interesting to realize how these reactions occur due to topological properties of space, rather than to the action of a local field. V.S. is grateful to Mario Castagnino for hospitality at the Instituto de Astronomía y Física del Espacio during a visit while this work was done.

  11. Open cluster evolutions in binary system: How they dissolved

    NASA Astrophysics Data System (ADS)

    Priyatikanto, R.; Arifyanto, M. I.; Wulandari, H. R. T.

    2014-03-01

    Binarity among stellar clusters in galaxy is such a reality which has been realized for a long time, but still hides several questions and problems to be solved. Some of binary star clusters are formed by close encounter, but the others are formed together from similar womb. Some of them undergo separation process, while the others are in the middle of merger toward common future. The products of merger binary star cluster have typical characteristics which differ from solo clusters, especially in their spatial distribution and their stellar members kinematics. On the other hand, these merger products still have to face dissolving processes triggered by both internal and external factors. In this study, we performed N-body simulations of merger binary clusters with different initial conditions. After merging, these clusters dissolve with greater mass-loss rate because of their angular momentum. These rotating clusters also experience more deceleration caused by external tidal field.

  12. Investigation into some characteristics of the mass-customized production paradigm

    NASA Astrophysics Data System (ADS)

    Tapper, Jerome; Sundar, Pratap S.; Kamarthi, Sagar V.

    2000-10-01

    In recent times, while markets are reaching their saturation limits and customers are becoming more demanding, a paradigm shift has been taking place from mass production to mass- customized production (MCP). The concept of mass customization (MC) focuses on satisfying a customer's unique needs with the help of new technologies such as Internet, digital product realization, and re-configurable production facilities. In MC the needs of an individual customer are translated into design, accordingly produced, and delivered to the customer. In this research three hypothesis related to MCP are investigated by the data/information collected from ten companies, which are engaged in MCP. These three hypothesis are (1) mass-customized production systems can be classified into make-to-stock MCP, assemble-to-order MCP, make-to-order MCP, engineer-to-order MC, and develop-to-order MCP, (2) in mass-customized production systems the process of customization eliminates customer sacrifice, and (3) mass-customized production systems can deliver products at mass-production cost. The preliminary study indicates that while the first hypothesis is valid, MCP companies rarely fulfill what is stated in the other two hypotheses.

  13. Principles to Products: Toward Realizing MOS 2.0

    NASA Technical Reports Server (NTRS)

    Bindschadler, Duane L.; Delp, Christopher L.

    2012-01-01

    This is a report on the Operations Revitalization Initiative, part of the ongoing NASA-funded Advanced Multi-Mission Operations Systems (AMMOS) program. We are implementing products that significantly improve efficiency and effectiveness of Mission Operations Systems (MOS) for deep-space missions. We take a multi-mission approach, in keeping with our organization's charter to "provide multi-mission tools and services that enable mission customers to operate at a lower total cost to NASA." Focusing first on architectural fundamentals of the MOS, we review the effort's progress. In particular, we note the use of stakeholder interactions and consideration of past lessons learned to motivate a set of Principles that guide the evolution of the AMMOS. Thus guided, we have created essential patterns and connections (detailed in companion papers) that are explicitly modeled and support elaboration at multiple levels of detail (system, sub-system, element...) throughout a MOS. This architecture is realized in design and implementation products that provide lifecycle support to a Mission at the system and subsystem level. The products include adaptable multi-mission engineering documentation that describes essentials such as operational concepts and scenarios, requirements, interfaces and agreements, information models, and mission operations processes. Because we have adopted a model-based system engineering method, these documents and their contents are meaningfully related to one another and to the system model. This means they are both more rigorous and reusable (from mission to mission) than standard system engineering products. The use of models also enables detailed, early (e.g., formulation phase) insight into the impact of changes (e.g., to interfaces or to software) that is rigorous and complete, allowing better decisions on cost or technical trades. Finally, our work provides clear and rigorous specification of operations needs to software developers, further enabling significant gains in productivity.

  14. Effects of microstructures on the performance of rare-earth-free MnBi magnetic materials and magnets

    NASA Astrophysics Data System (ADS)

    Nguyen, Vuong Van; Nguyen, Truong Xuan

    2018-03-01

    Since the solidification of MnBi alloys is peritectic, their microstructures always consist of the starting phases of Mn and Bi and the productive phase MnBi. The high performance of MnBi bulk magnets requires appropriate routes of preparing MnBi powders of high spontaneous magnetization Ms and large coercivity iHc as well a route of producing bulk magnets thereof. In these routes, the microstructures of arc-melted alloys, annealed alloys and magnets strongly related to the quality of powders and the performance of magnets. The paper proves that: i) The microstructure of fine Mn-inclusions embedded in the matrix of Bi is preferred for arc-melted alloys to realize the rapid evolution of the ferromagnetic phase inside them during their sequent annealing process; ii) The time-controlled annealing process plays a key role in controlling the microstructure with the main ferromagnetic phase matrix, in which the rest of Mn and the Bi accumulations are embedded; iii) The cold (in-liquid-nitrogen) ball milling annealed alloys is required for preparing a high quality powders with the preferred sub-micrometer microstructure without a Bi-decomposition; iv) The short-time warm compaction is crucial to fabricate dense, highly textured bulk magnets with the micrometer microstructure. The realization and control of these preferred microstructures figured in these routes enhance the chance of preparing MnBi bulk magnets with the energy product (BH)max larger than 8 MGOe.

  15. PLA realizations for VLSI state machines

    NASA Technical Reports Server (NTRS)

    Gopalakrishnan, S.; Whitaker, S.; Maki, G.; Liu, K.

    1990-01-01

    A major problem associated with state assignment procedures for VLSI controllers is obtaining an assignment that produces minimal or near minimal logic. The key item in Programmable Logic Array (PLA) area minimization is the number of unique product terms required by the design equations. This paper presents a state assignment algorithm for minimizing the number of product terms required to implement a finite state machine using a PLA. Partition algebra with predecessor state information is used to derive a near optimal state assignment. A maximum bound on the number of product terms required can be obtained by inspecting the predecessor state information. The state assignment algorithm presented is much simpler than existing procedures and leads to the same number of product terms or less. An area-efficient PLA structure implemented in a 1.0 micron CMOS process is presented along with a summary of the performance for a controller implemented using this design procedure.

  16. Case studies in machine vision integration

    NASA Astrophysics Data System (ADS)

    Ahlers, Rolf-Juergen

    1991-09-01

    Many countries in the world, e.g. Germany and Japan, depend on high export rates. It is therefore necessary for them to strive for a high degree of quality in the products and processes exported. The example of Japan shows in a significant manner that a competitor should not be feared just because he can offer cheaper products. They become a "source of danger" when these products also achieve a high degree of quality. Thus, survival in the market depends on the ability to recognize the implications of technical and economic developments, to draw the perhaps unpopular conclusions for production, and to make the right decisions. This particularly applies to measurement and inspection equipment for quality control. Here, besides electro-optical sensors in general, image processing systems play an important role because they can emulate the conventional form of visual inspection by a human operator — i.e., the methods used in industry when dealing with quality inspection and control. In combination with precision indexing tables and industrial robots, image processing systems can be extended to new fields of application. The great awareness of the potential applications of vision and image processing systems has led to a variety of realized applications, some of which will be described below under three topics: • electro-optical measurement systems, • automation of visual inspection tasks, and • robot guidance.

  17. Ease fabrication of PCR modular chip for portable DNA detection kit

    NASA Astrophysics Data System (ADS)

    Whulanza, Yudan; Aditya, Rifky; Arvialido, Reyhan; Utomo, Muhammad S.; Bachtiar, Boy M.

    2017-02-01

    Engineering a lab-on-a-chip (LoC) to perform the DNA polymerase chain reaction (PCR) for malaria detection is the ultimate goal of this study. This paper investigates the ability to fabricate an LoC kit using conventional method to achieve the lowest production cost by using existing fabrication process. It has been known that majority of LoC was made of polydimethylsiloxane (PDMS) which in this study was realized through a contact mold process. CNC milling process was utilized to create channel features in the range of 150-250 µm on the mold. Characterization on the milling process was done to understand the shrinkage/contraction between mold to product, roughness and also angle of contact of PDMS surface. Ultimately, this paper also includes analysis on flow measurement and heat distribution of an assembled LoC PCR kit. The results show that the achieved dimension of microchannel is 227 µm wide with a roughness of 0.01 µm. The flow measurement indicates a deviation with simulation in the range of 10%. A heat distribution through the kit is achieved following the three temperature zones as desired.

  18. High substrate uptake rates empower Vibrio natriegens as production host for industrial biotechnology.

    PubMed

    Hoffart, Eugenia; Grenz, Sebastian; Lange, Julian; Nitschel, Robert; Müller, Felix; Schwentner, Andreas; Feith, André; Lenfers-Lücker, Mira; Takors, Ralf; Blombach, Bastian

    2017-09-08

    The productivity of industrial fermentation processes is essentially limited by the biomass specific substrate consumption rate (q S ) of the applied microbial production system. Since q S depends on the growth rate (μ), we highlight the potential of the fastest growing non-pathogenic bacterium, Vibrio natriegens , as novel candidate for future biotechnological processes. V. natriegens grows rapidly in BHIN complex medium with a μ of up to 4.43 h -1 (doubling time of 9.4 min) as well as in minimal medium supplemented with various industrially relevant substrates. Bioreactor cultivations in minimal medium with glucose showed that V. natriegens possesses an exceptionally high q S under aerobic (3.90 ± 0.08 g g -1 h -1 ) and anaerobic (7.81 ± 0.71 g g -1 h -1 ) conditions. Fermentations with resting cells of genetically engineered V. natriegens under anaerobic conditions yielded an overall volumetric productivity of 0.56 ± 0.10 g alanine L -1 min -1 (i.e. 34 g L -1 h -1 ). These inherent properties render V. natriegens a promising new microbial platform for future industrial fermentation processes operating with high productivity. Importance Low conversion rates are one major challenge to realize microbial fermentation processes for the production of commodities operating competitively to existing petrochemical approaches. For this reason, we screened for a novel platform organism possessing superior characteristics to traditionally employed microbial systems. We identified the fast growing Vibrio natriegens which exhibits a versatile metabolism and shows striking growth and conversion rates, as a solid candidate to reach outstanding productivities. Due to these inherent characteristics V. natriegens can speed up common laboratory routines, is suitable for already existing production procedures, and forms an excellent foundation to engineer next generation bioprocesses. Copyright © 2017 American Society for Microbiology.

  19. Modular high power diode lasers with flexible 3D multiplexing arrangement optimized for automated manufacturing

    NASA Astrophysics Data System (ADS)

    Könning, Tobias; Bayer, Andreas; Plappert, Nora; Faßbender, Wilhelm; Dürsch, Sascha; Küster, Matthias; Hubrich, Ralf; Wolf, Paul; Köhler, Bernd; Biesenbach, Jens

    2018-02-01

    A novel 3-dimensional arrangement of mirrors is used to re-arrange beams from 1-D and 2-D high power diode laser arrays. The approach allows for a variety of stacking geometries, depending on individual requirements. While basic building blocks, including collimating optics, always remain the same, most adaptations can be realized by simple rearrangement of a few optical components. Due to fully automated alignment processes, the required changes can be realized in software by changing coordinates, rather than requiring customized mechanical components. This approach minimizes development costs due to its flexibility, while reducing overall product cost by using similar building blocks for a variety of products and utilizing a high grade of automation. The modules can be operated with industrial grade water, lowering overall system and maintenance cost. Stackable macro coolers are used as the smallest building block of the system. Each cooler can hold up to five diode laser bars. Micro optical components, collimating the beam, are mounted directly to the cooler. All optical assembly steps are fully automated. Initially, the beams from all laser bars propagate in the same direction. Key to the concept is an arrangement of deflectors, which re-arrange the beams into a 2-D array of the desired shape and high fill factor. Standard multiplexing techniques like polarization- or wavelengths-multiplexing have been implemented as well. A variety of fiber coupled modules ranging from a few hundred watts of optical output power to multiple kilowatts of power, as well as customized laser spot geometries like uniform line sources, have been realized.

  20. EARSEC SAR processing system

    NASA Astrophysics Data System (ADS)

    Protheroe, Mark; Sloggett, David R.; Sieber, Alois J.

    1994-12-01

    Traditionally, the production of high quality Synthetic Aperture Radar imagery has been an area where a potential user would have to expend large amounts of money in either the bespoke development of a processing chain dedicated to his requirements or in the purchase of a dedicated hardware platform adapted using accelerator boards and enhanced memory management. Whichever option the user adopted there were limitations based on the desire for a realistic throughput in data load and time. The user had a choice, made early in the purchase, for either a system that adopted innovative algorithmic manipulation, to limit the processing time of the purchase of expensive hardware. The former limits the quality of the product, while the latter excludes the user from any visibility into the processing chain. Clearly there was a need for a SAR processing architecture that gave the user a choice into the methodology to be adopted for a particular processing sequence, allowing him to decide on either a quick (lower quality) product or a detailed slower (high quality) product, without having to change the algorithmic base of his processor or the hardware platform. The European Commission, through the Advanced Techniques unit of the Joint Research Centre (JRC) Institute for Remote Sensing at Ispra in Italy, realizing the limitations on current processing abilities, initiated its own program to build airborne SAR and Electro-Optical (EO) sensor systems. This program is called the European Airborne Remote Sensing Capabilities (EARSEC) program. This paper describes the processing system developed for the airborne SAR sensor system. The paper considers the requirements for the system and the design of the EARSEC Airborne SAR Processing System. It highlights the development of an open SAR processing architecture where users have full access to intermediate products that arise from each of the major processing stages. It also describes the main processing stages in the overall architecture and illustrates the results of each of the key stages in the processor.

  1. Flame Synthesis Of Single-Walled Carbon Nanotubes And Nanofibers

    NASA Technical Reports Server (NTRS)

    Wal, Randy L. Vander; Berger, Gordon M.; Ticich, Thomas M.

    2003-01-01

    Carbon nanotubes are widely sought for a variety of applications including gas storage, intercalation media, catalyst support and composite reinforcing material [1]. Each of these applications will require large scale quantities of CNTs. A second consideration is that some of these applications may require redispersal of the collected CNTs and attachment to a support structure. If the CNTs could be synthesized directly upon the support to be used in the end application, a tremendous savings in post-synthesis processing could be realized. Therein we have pursued both aerosol and supported catalyst synthesis of CNTs. Given space limitations, only the aerosol portion of the work is outlined here though results from both thrusts will be presented during the talk. Aerosol methods of SWNT, MWNT or nanofiber synthesis hold promise of large-scale production to supply the tonnage quantities these applications will require. Aerosol methods may potentially permit control of the catalyst particle size, offer continuous processing, provide highest product purity and most importantly, are scaleable. Only via economy of scale will the cost of CNTs be sufficient to realize the large-scale structural and power applications on both earth and in space. Present aerosol methods for SWNT synthesis include laser ablation of composite metalgraphite targets or thermal decomposition/pyrolysis of a sublimed or vaporized organometallic [2]. Both approaches, conducted within a high temperature furnace, have produced single-walled nanotubes (SWNTs). The former method requires sophisticated hardware and is inherently limited by the energy deposition that can be realized using pulsed laser light. The latter method, using expensive organometallics is difficult to control for SWNT synthesis given a range of gasparticle mixing conditions along variable temperature gradients; multi-walled nanotubes (MWNTs) are a far more likely end products. Both approaches require large energy expenditures and produce CNTs at prohibitive costs, around $500 per gram. Moreover these approaches do not possess demonstrated scalability. In contrast to these approaches, flame synthesis can be a very energy efficient, low-cost process [3]; a portion of the fuel serves as the heating source while the remainder serves as reactant. Moreover, flame systems are geometrically versatile as illustrated by innumerable boiler and furnace designs. Addressing scalability, flame systems are commercially used for producing megatonnage quantities of carbon black [4]. Although it presents a complex chemically reacting flow, a flame also offers many variables for control, e.g. temperature, chemical environment and residence times [5]. Despite these advantages, there are challenges to scaling flame synthesis as well.

  2. Realization of guitar audio effects using methods of digital signal processing

    NASA Astrophysics Data System (ADS)

    Buś, Szymon; Jedrzejewski, Konrad

    2015-09-01

    The paper is devoted to studies on possibilities of realization of guitar audio effects by means of methods of digital signal processing. As a result of research, some selected audio effects corresponding to the specifics of guitar sound were realized as the real-time system called Digital Guitar Multi-effect. Before implementation in the system, the selected effects were investigated using the dedicated application with a graphical user interface created in Matlab environment. In the second stage, the real-time system based on a microcontroller and an audio codec was designed and realized. The system is designed to perform audio effects on the output signal of an electric guitar.

  3. Cooperation between humans and robots in fine assembly

    NASA Astrophysics Data System (ADS)

    Jalba, C. K.; Konold, P.; Rapp, I.; Mann, C.; Muminovic, A.

    2017-01-01

    The development of ever smaller components in manufacturing processes require handling, assembling and testing of miniature similar components. The human eye meets its optical limits with ongoing miniaturization of parts, due to the fact that it is not able to detect particles with a size smaller than 0.11 mm or register distances below 0.07 mm - like separating gaps. After several hours of labour, workers cannot accurately differentiate colour nuances as well as constant quality of work cannot be guaranteed. Assembly is usually done with tools, such as microscopes, magnifiers or digital measuring devices. Due to the enormous mental concentration, quickly a fatigue process sets in. This requires breaks or change of task and reduces productivity. Dealing with handling devices such as grippers, guide units and actuators for component assembling, requires a time consuming training process. Often productivity increase is first achieved after years of daily training. Miniaturizations are ubiquitously needed, for instance in the surgery. Very small add-on instruments must be provided. In measurement, e.g. it is a technological must and a competitive advantage, to determine required data with a small-as-possible, highest-possible-resolution sensor. Solution: The realization of a flexible universal workstation, using standard robotic systems and image processing devices in cooperation with humans, where workers are largely freed up from highly strenuous physical and fine motoric work, so that they can do productive work monitoring and adjusting the machine assisted production process.

  4. The Physics of Ultracold Sr2 Molecules: Optical Production and Precision Measurement

    NASA Astrophysics Data System (ADS)

    Osborn, Christopher Butler

    Colloidal quantum dots have desirable optical properties which can be exploited to realize a variety of photonic devices and functionalities. However, colloidal dots have not had a pervasive utility in photonic devices because of the absence of patterning methods. The electronic chip industry is highly successful due to the well-established lithographic procedures. In this thesis we borrow ideas from the semiconductor industry to develop lithographic techniques that can be used to pattern colloidal quantum dots while ensuring that the optical properties of the quantum dots are not affected by the process. In this thesis we have developed colloidal quantum dot based waveguide structures for amplification and switching applications for all-optical signal processing. We have also developed colloidal quantum dot based light emitting diodes. We successfully introduced CdSe/ZnS quantum dots into a UV curable photo-resist, which was then patterned to realize active devices. In addition, "passive" devices (devices without quantum dots) were integrated to "active" devices via waveguide couplers. Use of photo-resist devices offers two distinct advantages. First, they have low scattering loss and secondly, they allow good fiber to waveguide coupling efficiency due to the low refractive index which allows for large waveguide cross-sections while supporting single mode operation. Practical planar photonic devices and circuits incorporating both active and passive structures can now be realized, now that we have patterning capabilities of quantum dots while maintaining the original optical attributes of the system. In addition to the photo-resist host, we also explored the incorporation of colloidal quantum dots into a dielectric silicon dioxide and silicon nitride one-dimensional microcavity structures using low temperature plasma enhanced chemical vapor deposition. This material system can be used to realize microcavity light emitting diodes that can be realized on any substrate. As a proof of concept demonstration we show a 1550 nm emitting all-dielectric vertical cavity structure embedded with PbS quantum dots. Enhancement in spontaneous emission from the dots embedded in the microcavity is also demonstrated.

  5. Geological characterization of agricultural terraces as a tool for the territorial safeguard and for the valorization of "Terroir"

    NASA Astrophysics Data System (ADS)

    Brancucci, Gerardo; Brancucci, Michele; Marescotti, Pietro; Poggi, Eugenio; Solimano, Monica; Vegnuti, Roberto; Giostrella, Paola; Tarolli, Paolo

    2017-04-01

    The progressive abandonment of the terraced areas of Liguria (NW Italy) is determining an inexorable land degradation, which causes, among other things, the erosive processes and the slope failure. Several studies highlighted the need of strategies for the recovery of abandoned agricultural lands by encouraging the productive reuse. Nevertheless, it is well known that agricultural activities in rural areas with steep slopes are strongly penalized by the high production costs determined by the adverse geomorphological conditions. For these reasons, one of the possible solutions is to encourage the production of high-quality agricultural crops, and to promote the uniqueness of the products. The uniqueness of the local products can be promoted not only by means of marketing strategy, mostly based on historical and traditional aspects of the productions, but also by correlating the product with the geological features (e.g., lithology, mineralogy and geochemistry) of the agricultural soils and parental rocks. These features are typically peculiar of a geographic area and thus strictly correlated with the site of production. This approach, together with the biological characterization of the crop, can link the cultivar to the geographical area of production thus evidencing peculiarities that are inimitable elsewhere. With this work we present the experimental results of investigations performed on several types of agricultural products (grapes and wines, olives and olive oils, apples) as well as on wild mushroom of the Boletus family. The analyses have been carried out either in laboratory and by means of field portable instruments (FP-EDXRF and FP-FTIR) which permitted a large number of in situ analyses, in a cost efficient and timely manner, thus allowing the realization of high spatial resolution compositional maps. This analytical approach also resulted particularly effective to improve the information obtained by traditional pedological and agronomical investigations. The results allowed to realize the "geological label of the product®" which is an assurance label that certifies the peculiar geological features of the area of production. The label contains a QRcode which allows to obtain detailed information about the soil composition, geological and geomorphological information and their relationships with the organoleptic characteristics of the product. The geological label of the product may have significant implications for the sales and marketing chain since it allows to commercialize higher value product characterized by: i) organoleptic and environmental quality; ii) uniqueness of the area of production; iii) geographical identity of the crops. By associating these information with the valorization of the terroir, the territorial marketing may be strongly improved ensuring the development of the territories and the realization of a closer relationship between the customer, the Company and consumers. The value created by this potential brand can attract investment for the recovery of abandoned agricultural lands and for the agricultural terraces management with positive effects on the increase of productivity and, consequently, on the maintenance, management and territorial safeguard.

  6. Selection of Compositions in Ti-Cr-C-Steel, Ti-B, Ti-B-Me Systems and Establishing Synthesis Parameters for Obtaining Product by “SHS-Electrical Rolling”

    NASA Astrophysics Data System (ADS)

    Aslamazashvili, Zurab; Tavadze, Giorgi; Chikhradze, Mikheil; Namicheishvili, Teimuraz; Melashvili, Zaqaria

    2017-12-01

    For the production materials by the proposed Self-propagating High-Temperature Synthesis (SHS) - Electric Rolling method, there are no limitations in the length of the material and the width only depends on the length of rolls. The innovation method enables to carry out the process in nonstop regime, which is possible by merging energy consuming SHS method and Electrical Rolling. For realizing the process it is mandatory and sufficient, that initial components, after initiation by thermal pulse, could interaction with the heat emission, which itself ensures the self-propagation of synthesis front in lieu of heat transfer in the whole sample. Just after that process, the rolls instantly start rotation with the set speed to ensure the motion of material. This speed should be equal to the speed of propagation of synthesis front. The synthesized product in hot plastic condition is delivered to the rolls in nonstop regime, simultaneously, providing the current in deformation zone in order to compensate the energy loses. As a result by using the innovation SHS -Electrical Rolling technology we obtain long dimensional metal-ceramic product. In the presented paper optimal compositions of SHS chasms were selected in Ti-Cr-C-Steel, Ti-B and Ti-B-Me systems. For the selection of the compounds the thermodynamic analysis has been carried out which enabled to determine adiabatic temperature of synthesis theoretically and to determine balanced concentrations of synthesized product at synthesis temperature. Thermodynamic analysis also gave possibility to determine optimal compositions of chasms and define the conditions, which are important for correct realization of synthesis process. For obtaining non porous materials and product by SHS-Electrical Rolling, it is necessary to select synthesis and compacting parameters correctly. These parameters are the pressure and the time. In Ti-Cr-C-Steel, Ti-B and Ti-B-Me systems the high quality (nonporous or low porosity <2%) of materials and product is directly depended on the liquid phase content just after the passing of synthesis front in the sample. The more content of liquid phase provides the higher quality of material. The content of liquid phase itself depends on synthesis parameters: speed and temperature of synthesis. The higher the speed and temperature of synthesis we have, higher the content of liquid phase is formed. The speed and the temperature of synthesis depend on the Δρ relative density of sample formed from initial chasm, this mean it depends on the pressure of formation of the sample. The paper describes the results of determination of optimal pressures in Ti-Cr-C-Steel, Ti-B and Ti-B-Me systems. Their values are defined as 50-70 MPa, 180-220 MPa and 45-70 MPa.

  7. Entropy Production in Convective Hydrothermal Systems

    NASA Astrophysics Data System (ADS)

    Boersing, Nele; Wellmann, Florian; Niederau, Jan

    2016-04-01

    Exploring hydrothermal reservoirs requires reliable estimates of subsurface temperatures to delineate favorable locations of boreholes. It is therefore of fundamental and practical importance to understand the thermodynamic behavior of the system in order to predict its performance with numerical studies. To this end, the thermodynamic measure of entropy production is considered as a useful abstraction tool to characterize the convective state of a system since it accounts for dissipative heat processes and gives insight into the system's average behavior in a statistical sense. Solving the underlying conservation principles of a convective hydrothermal system is sensitive to initial conditions and boundary conditions which in turn are prone to uncertain knowledge in subsurface parameters. There exist multiple numerical solutions to the mathematical description of a convective system and the prediction becomes even more challenging as the vigor of convection increases. Thus, the variety of possible modes contained in such highly non-linear problems needs to be quantified. A synthetic study is carried out to simulate fluid flow and heat transfer in a finite porous layer heated from below. Various two-dimensional models are created such that their corresponding Rayleigh numbers lie in a range from the sub-critical linear to the supercritical non-linear regime, that is purely conductive to convection-dominated systems. Entropy production is found to describe the transient evolution of convective processes fairly well and can be used to identify thermodynamic equilibrium. Additionally, varying the aspect ratio for each Rayleigh number shows that the variety of realized convection modes increases with both larger aspect ratio and higher Rayleigh number. This phenomenon is also reflected by an enlarged spread of entropy production for the realized modes. Consequently, the Rayleigh number can be correlated to the magnitude of entropy production. In cases of moderate Rayleigh number and moderate aspect ratio, entropy production even enables to predict a preferred convection mode for a model with homogeneous parameter distribution. As a general rule, the thermodynamic measure of entropy production can be used to analyze uncertainties accompanied by modelling convective hydrothermal systems. Without considering any probability distributions of input data, this synthetic study shows that a higher entropy production implies a lower ability to uniquely predict the convection pattern. This in turn means that the uncertainty in estimating subsurface temperatures is higher.

  8. Government and industry interactions in the development of clock technology

    NASA Technical Reports Server (NTRS)

    Hellwig, H.

    1981-01-01

    It appears likely that everyone in the time and frequency community can agree on goals to be realized through the expenditure of resources. These goals are the same as found in most fields of technology: lower cost, better performance, increased reliability, small size and lower power. Related aspects are examined in the process of clock and frequency standard development. Government and industry are reviewed in a highly interactive role. These interactions include judgements on clock performance, what kind of clock, expenditure of resources, transfer of ideas or hardware concepts from government to industry, and control of production. Successful clock development and production requires a government/industry relationship which is characterized by long-term continuity, multidisciplinary team work, focused funding and a separation of reliability and production oriented tasks from performance improvement/research type efforts.

  9. Execution of Educational Mechanical Production Programs for School Children

    NASA Astrophysics Data System (ADS)

    Itoh, Nobuhide; Itoh, Goroh; Shibata, Takayuki

    The authors are conducting experience-based engineering educational programs for elementary and junior high school students with the aim to provide a chance for them to experience mechanical production. As part of this endeavor, we planned and conducted a program called “Fabrication of Original Magnet Plates by Casting” for elementary school students. This program included a course for leading nature laws and logical thinking method. Prior to the program, a preliminary program was applied to school teachers to get comments and to modify for the program accordingly. The children responded excellently to the production process which realizes their ideas, but it was found that the course on natural laws and logical methods need to be improved to draw their interest and attention. We will continue to plan more effective programs, deepening ties with the local community.

  10. Technology of High-speed Direct Laser Deposition from Ni-based Superalloys

    NASA Astrophysics Data System (ADS)

    Klimova-Korsmik, Olga; Turichin, Gleb; Zemlyakov, Evgeniy; Babkin, Konstantin; Petrovsky, Pavel; Travyanov, Andrey

    Recently, additive manufacturing is the one of most perspective technologies; it can replace conventional methods of casting and subsequent time-consuming machining. One of the most interesting additive technologies - high-speed direct laser deposition (HSDLD) allows realizing heterophase process during the manufacturing, which there is process takes place with a partial melting of powder. This is particularly important for materials, which are sensitive to strong fluctuations of temperature treatment regimes, like nickel base alloys with high content of gamma prime phase. This alloys are interested for many industrial areas, mostly there are used in engine systems, aircraft and shipbuilding, aeronautics. Heating and cooling rates during the producing process determine structure and affect on its properties. Using HSDLD process it possible to make a products from Ni superalloys with ultrafine microstructure and satisfactory mechanical characteristics without special subsequent heatreatment.

  11. Modelling technological process of ion-exchange filtration of fluids in porous media

    NASA Astrophysics Data System (ADS)

    Ravshanov, N.; Saidov, U. M.

    2018-05-01

    Solution of an actual problem related to the process of filtration and dehydration of liquid and ionic solutions from gel particles and heavy ionic compounds is considered in the paper. This technological process is realized during the preparation and cleaning of chemical solutions, drinking water, pharmaceuticals, liquid fuels, products for public use, etc. For the analysis, research, determination of the main parameters of the technological process and operating modes of filter units and for support in managerial decision-making, a mathematical model is developed. Using the developed model, a series of computational experiments on a computer is carried out. The results of numerical calculations are illustrated in the form of graphs. Based on the analysis of numerical experiments, the conclusions are formulated that serve as the basis for making appropriate managerial decisions.

  12. EPOS: Integrating seismological Research Infrastructures within Europe

    NASA Astrophysics Data System (ADS)

    Eck Van, Torild; Clinton, John; Haslinger, Florian; Michelini, Alberto

    2013-04-01

    Seismological data, products and models are currently produced in Europe within individual countries or research organizations, and with the contribution of coordinating organizations like ORFEUS and EMSC. In spite of these partly scattered resources, significant scientific results are obtained, excellent monitoring and information systems are operational and a huge amount of research quality data is being archived and disseminated. The seismological community, however, realizes that an effective European-scale integration of seismological and related geophysical data, products and models, combined with broad and easy access, is needed to facilitate future top level geoscience, for example, to appropriately harness the technological advancements enabling large scale and near-real time data processing. Here we present the technical concepts and developments within European seismology that will build the next generation of integrated services. Within the EPOS initiative and a number of related projects, where seismology infrastructure and IT developments are merging, in depth discussions are on-going on how to realize an effective integration. Concepts and visions addressing the obviously complex challenges resulting from the current highly distributed facilities and resources in Europe are emerging and are already partly being implemented. We will provide an overview of developments within key EU projects (NERA, VERCE, COOPEUS, EUDAT, REAKT, COMMIT, etc) and demonstrate how these are in coherence with EPOS and other on-going global initiatives. Within seismology current focus is on addressing IT related challenges to a) organize distributed data archives, develop metadata attributes for improved data searching, specifically including quality indicators, and define products from data and/or models, and b) define and create(on-line) monitoring, data access and processing tools. While developments to meet those challenges originate partly from within the community itself, it is important to harvest relevant ideas and tools from other scientific communities dealing with similar issues. We will present a short summary of those developments and how they fit within the proposed visions and concepts. These integration developments address a wide framework of seismological services that include: basic seismological data services (waveform data from velocity and acceleration sensors from land and underwater sites); seismological data products (source mechanism and process estimates, earthquake catalogues, structural and tomography model estimations); seismological models (synthetic waveforms, earth and earthquake source models, hazard models).Our aim is to build significantlyimproved seismological services and valuable products for multidisciplinary earth science research.

  13. Goals, Big and Small

    ERIC Educational Resources Information Center

    Walkow, Martin

    2012-01-01

    This dissertation explores the interaction of syntax and morphology in the morphological realization of AGREE-relations. I present two case studies of derivational interactions of AGREE-processes where the morphological realization of the later processes are affected by the earlier ones. The two cases studied differ in the way probes and goals…

  14. The Relationship between Environmental Turbulence, Management Support, Organizational Collaboration, Information Technology Solution Realization, and Process Performance, in Healthcare Provider Organizations

    ERIC Educational Resources Information Center

    Muglia, Victor O.

    2010-01-01

    The Problem: The purpose of this study was to investigate relationships between environmental turbulence, management support, organizational collaboration, information technology solution realization, and process performance in healthcare provider organizations. Method: A descriptive/correlational study of Hospital medical services process…

  15. Catalyst-free dehydrative α-alkylation of ketones with alcohols: green and selective autocatalyzed synthesis of alcohols and ketones.

    PubMed

    Xu, Qing; Chen, Jianhui; Tian, Haiwen; Yuan, Xueqin; Li, Shuangyan; Zhou, Chongkuan; Liu, Jianping

    2014-01-03

    Direct dehydrative α-alkylation reactions of ketones with alcohols are now realized under simple, practical, and green conditions without using external catalysts. These catalyst-free autocatalyzed alkylation methods can efficiently afford useful alkylated ketone or alcohol products in a one-pot manner and on a large scale by CC bond formation of the in situ generated intermediates with subsequent controllable and selective Meerwein-Pondorf-Verley-Oppenauer-type redox processes. Copyright © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  16. Pre-feasibility study for construction of a commercial coal hydrogenation plant

    NASA Astrophysics Data System (ADS)

    Hahn, W.; Wilhelm, H.; Kleinhueckelkotten, H.; Schmedeshagen, B.

    1982-11-01

    The technical problems, a suitable site and the unsatisfactory economics hinder the realization of a commercial coal liquefaction plant in Germany were identified. It is found that a plant for hydrogenation of coal and heavy oil according to the updated bergius-Pier process can be built. The improvement of acceptable reactor loading and increase of product yield was considered. The infrastructure aspects of a site for the plant which covers 300 hectars as well as eventually existing atmospheric pollution conditions in the environment are also considered.

  17. Feature based Weld-Deposition for Additive Manufacturing of Complex Shapes

    NASA Astrophysics Data System (ADS)

    Panchagnula, Jayaprakash Sharma; Simhambhatla, Suryakumar

    2018-06-01

    Fabricating functional metal parts using Additive Manufacturing (AM) is a leading trend. However, realizing overhanging features has been a challenge due to the lack of support mechanism for metals. Powder-bed fusion techniques like, Selective Laser Sintering (SLS) employ easily-breakable-scaffolds made of the same material to realize the overhangs. However, the same approach is not extendible to deposition processes like laser or arc based direct energy deposition processes. Although it is possible to realize small overhangs by exploiting the inherent overhanging capability of the process or by blinding some small features like holes, the same cannot be extended for more complex geometries. The current work presents a novel approach for realizing complex overhanging features without the need of support structures. This is possible by using higher order kinematics and suitably aligning the overhang with the deposition direction. Feature based non-uniform slicing and non-uniform area-filling are some vital concepts required in realizing the same and are briefly discussed here. This method can be used to fabricate and/or repair fully dense and functional components for various engineering applications. Although this approach has been implemented for weld-deposition based system, the same can be extended to any other direct energy deposition processes also.

  18. Limitations of discrete-time quantum walk on a one-dimensional infinite chain

    NASA Astrophysics Data System (ADS)

    Lin, Jia-Yi; Zhu, Xuanmin; Wu, Shengjun

    2018-04-01

    How well can we manipulate the state of a particle via a discrete-time quantum walk? We show that the discrete-time quantum walk on a one-dimensional infinite chain with coin operators that are independent of the position can only realize product operators of the form eiξ A ⊗1p, which cannot change the position state of the walker. We present a scheme to construct all possible realizations of all the product operators of the form eiξ A ⊗1p. When the coin operators are dependent on the position, we show that the translation operators on the position can not be realized via a DTQW with coin operators that are either the identity operator 1 or the Pauli operator σx.

  19. [Symbiotic interactions of corynebacteria and lactobacilli in realization of oxidative mechanisms of antagonism].

    PubMed

    Cherkasov, S V; Gladysheva, I V; Bukharin, O V

    2012-01-01

    Study the interaction of vaginal corynebacteria and lactobacilli in realization of oxidative mechanism of antagonistic relations of bacteria. Effect of supernatants of corynebacteria inhibiting catalase on antagonism of peroxide producing lactobacilli to Staphylococcus aureus was studied. High frequency (55.5 - 72.7%) of potentiating of antagonism of lactobacilli with medium and high level of hydrogen peroxide production under the effect of supernatants of corynebacteria inhibiting catalase was established. The frequency of potentiation of antagonism of lactobacilli and corynebacteriae depended on the intensity of hydrogen peroxide production and on the ability of corynebacteria to suppress catalase of staphylococci. Potentiation of antagonism to S. aureus of peroxide producing lactobacilli and corynebacteria with catalase inhibitors gives evidence on realization of oxidative bacterial mechanism of colonization resistance in human organism.

  20. Self-reporting inhibitors: single crystallization process to get two optically pure enantiomers.

    PubMed

    Wan, Xinhua; Ye, Xichong; Cui, Jiaxi; Li, Bowen; Li, Na; Zhang, Jie

    2018-05-22

    Collection of two optically pure enantiomers in a single crystallization process can significantly increase the chiral separation efficiency but it's hard to realize nowadays. Herein we describe, for the first time, a self-reporting strategy for visualizing the crystallization process by a kind of dyed self-assembled inhibitors made from the copolymers with tri(ethylene glycol)-grafting polymethylsiloxane as main chains and poly(N6-methacryloyl-L-lysine) as side chains. When applied with seeds together for the fractional crystallization of conglomerates, the inhibitors can label the formation of the secondary crystals and guide us to completely separate the crystallization process of two enantiomers with colorless crystals as the first product and red crystals as the secondary product. This method leads to high optical purity of D/L-Asn·H2O (99.9 ee% for D-crystals and 99.5 ee% for L-crystals) in a single crystallization process. Moreover, it requires low feeding amount of additives and shows excellent recyclability. We foresee its great potential in developing novel chiral separation methods that can be used in different scales. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  1. Novel Catalysts and Processing Technologies for Production of Aerospace Fuels from Non-Petroleum Raw Materials

    NASA Technical Reports Server (NTRS)

    Hepp, Aloysius F.; Kulis, Michael J.; Psarras, Peter C.; Ball, David W.; Timko, Michael T.; Wong, Hsi-Wu; Peck, Jay; Chianelli, Russell R.

    2014-01-01

    Transportation fuels production (including aerospace propellants) from non-traditional sources (gases, waste materials, and biomass) has been an active area of research and development for decades. Reducing terrestrial waste streams simultaneous with energy conversion, plentiful biomass, new low-cost methane sources, and/or extra-terrestrial resource harvesting and utilization present significant technological and business opportunities being realized by a new generation of visionary entrepreneurs. We examine several new approaches to catalyst fabrication and new processing technologies to enable utilization of these nontraditional raw materials. Two basic processing architectures are considered: a single-stage pyrolysis approach that seeks to basically re-cycle hydrocarbons with minimal net chemistry or a two-step paradigm that involves production of supply or synthesis gas (mainly carbon oxides and H2) followed by production of fuel(s) via Sabatier or methanation reactions and/or Fischer-Tröpsch synthesis. Optimizing the fraction of product stream relevant to targeted aerospace (and other transportation) fuels via modeling, catalyst fabrication and novel reactor design are described. Energy utilization is a concern for production of fuels for either terrestrial or space operations; renewable sources based on solar energy and/or energy efficient processes may be mission enabling. Another important issue is minimizing impurities in the product stream(s), especially those potentially posing risks to personnel or operations through (catalyst) poisoning or (equipment) damage. Technologies being developed to remove (and/or recycle) heteroatom impurities are briefly discussed as well as the development of chemically robust catalysts whose activities are not diminished during operation. The potential impacts on future missions by such new approaches as well as balance of system issues are addressed.

  2. Novel Catalysts and Processing Technologies for Production of Aerospace Fuels from Non-Petroleum Raw Materials

    NASA Technical Reports Server (NTRS)

    Hepp, A. F.; Kulis, M. J.; Psarras, P. C.; Ball, D. W.; Timko, M. T.; Wong, H.-W.; Peck, J.; Chianelli, R. R.

    2014-01-01

    Transportation fuels production (including aerospace propellants) from non-traditional sources (gases, waste materials, and biomass) has been an active area of research and development for decades. Reducing terrestrial waste streams simultaneous with energy conversion, plentiful biomass, new low-cost methane sources, and/or extra-terrestrial resource harvesting and utilization present significant technological and business opportunities being realized by a new generation of visionary entrepreneurs. We examine several new approaches to catalyst fabrication and new processing technologies to enable utilization of these non-traditional raw materials. Two basic processing architectures are considered: a single-stage pyrolysis approach that seeks to basically re-cycle hydrocarbons with minimal net chemistry or a two-step paradigm that involves production of supply or synthesis gas (mainly carbon oxides and hydrogen) followed by production of fuel(s) via Sabatier or methanation reactions and/or Fischer-Tropsch synthesis. Optimizing the fraction of product stream relevant to targeted aerospace (and other transportation) fuels via modeling, catalyst fabrication and novel reactor design are described. Energy utilization is a concern for production of fuels for either terrestrial or space operations; renewable sources based on solar energy and/or energy efficient processes may be mission enabling. Another important issue is minimizing impurities in the product stream(s), especially those potentially posing risks to personnel or operations through (catalyst) poisoning or (equipment) damage. Technologies being developed to remove (and/or recycle) heteroatom impurities are briefly discussed as well as the development of chemically robust catalysts whose activity are not diminished during operation. The potential impacts on future missions by such new approaches as well as balance of system issues are addressed.

  3. Optimizing process and equipment efficiency using integrated methods

    NASA Astrophysics Data System (ADS)

    D'Elia, Michael J.; Alfonso, Ted F.

    1996-09-01

    The semiconductor manufacturing industry is continually riding the edge of technology as it tries to push toward higher design limits. Mature fabs must cut operating costs while increasing productivity to remain profitable and cannot justify large capital expenditures to improve productivity. Thus, they must push current tool production capabilities to cut manufacturing costs and remain viable. Working to continuously improve mature production methods requires innovation. Furthermore, testing and successful implementation of these ideas into modern production environments require both supporting technical data and commitment from those working with the process daily. At AMD, natural work groups (NWGs) composed of operators, technicians, engineers, and supervisors collaborate to foster innovative thinking and secure commitment. Recently, an AMD NWG improved equipment cycle time on the Genus tungsten silicide (WSi) deposition system. The team used total productive manufacturing (TPM) to identify areas for process improvement. Improved in-line equipment monitoring was achieved by constructing a real time overall equipment effectiveness (OEE) calculator which tracked equipment down, idle, qualification, and production times. In-line monitoring results indicated that qualification time associated with slow Inspex turn-around time and machine downtime associated with manual cleans contributed greatly to reduced availability. Qualification time was reduced by 75% by implementing a new Inspex monitor pre-staging technique. Downtime associated with manual cleans was reduced by implementing an in-situ plasma etch back to extend the time between manual cleans. A designed experiment was used to optimize the process. Time between 18 hour manual cleans has been improved from every 250 to every 1500 cycles. Moreover defect density realized a 3X improvement. Overall, the team achieved a 35% increase in tool availability. This paper details the above strategies and accomplishments.

  4. A recent Cleanroom success story: The Redwing project

    NASA Technical Reports Server (NTRS)

    Hausler, Philip A.

    1992-01-01

    Redwing is the largest completed Cleanroom software engineering project in IBM, both in terms of lines of code and project staffing. The product provides a decision-support facility that utilizes artificial intelligence (AI) technology for predicting and preventing complex operating problems in an MVS environment. The project used the Cleanroom process for development and realized a defect rate of 2.6 errors/KLOC, measured from first execution. This represents the total amount of errors that were found in testing and installation at three field test sites. Development productivity was 486 LOC/PM, which included all development labor expended in design specification through completion of incremental testing. In short, the Redwing team produced a complex systems software product with an extraordinarily low error rate, while maintaining high productivity. All of this was accomplished by a project team using Cleanroom for the first time. An 'introductory implementation' of Cleanroom was defined and used on Redwing. This paper describes the quality and productivity results, the Redwing project, and how Cleanroom was implemented.

  5. Databases and coordinated research projects at the IAEA on atomic processes in plasmas

    NASA Astrophysics Data System (ADS)

    Braams, Bastiaan J.; Chung, Hyun-Kyung

    2012-05-01

    The Atomic and Molecular Data Unit at the IAEA works with a network of national data centres to encourage and coordinate production and dissemination of fundamental data for atomic, molecular and plasma-material interaction (A+M/PMI) processes that are relevant to the realization of fusion energy. The Unit maintains numerical and bibliographical databases and has started a Wiki-style knowledge base. The Unit also contributes to A+M database interface standards and provides a search engine that offers a common interface to multiple numerical A+M/PMI databases. Coordinated Research Projects (CRPs) bring together fusion energy researchers and atomic, molecular and surface physicists for joint work towards the development of new data and new methods. The databases and current CRPs on A+M/PMI processes are briefly described here.

  6. Synthesis and Process Optimization of Electrospun PEEK-Sulfonated Nanofibers by Response Surface Methodology

    PubMed Central

    Boaretti, Carlo; Roso, Martina; Lorenzetti, Alessandra; Modesti, Michele

    2015-01-01

    In this study electrospun nanofibers of partially sulfonated polyether ether ketone have been produced as a preliminary step for a possible development of composite proton exchange membranes for fuel cells. Response surface methodology has been employed for the modelling and optimization of the electrospinning process, using a Box-Behnken design. The investigation, based on a second order polynomial model, has been focused on the analysis of the effect of both process (voltage, tip-to-collector distance, flow rate) and material (sulfonation degree) variables on the mean fiber diameter. The final model has been verified by a series of statistical tests on the residuals and validated by a comparison procedure of samples at different sulfonation degrees, realized according to optimized conditions, for the production of homogeneous thin nanofibers. PMID:28793427

  7. Synthesis and Process Optimization of Electrospun PEEK-Sulfonated Nanofibers by Response Surface Methodology.

    PubMed

    Boaretti, Carlo; Roso, Martina; Lorenzetti, Alessandra; Modesti, Michele

    2015-07-07

    In this study electrospun nanofibers of partially sulfonated polyether ether ketone have been produced as a preliminary step for a possible development of composite proton exchange membranes for fuel cells. Response surface methodology has been employed for the modelling and optimization of the electrospinning process, using a Box-Behnken design. The investigation, based on a second order polynomial model, has been focused on the analysis of the effect of both process (voltage, tip-to-collector distance, flow rate) and material (sulfonation degree) variables on the mean fiber diameter. The final model has been verified by a series of statistical tests on the residuals and validated by a comparison procedure of samples at different sulfonation degrees, realized according to optimized conditions, for the production of homogeneous thin nanofibers.

  8. Shrinkage estimation of the realized relationship matrix

    USDA-ARS?s Scientific Manuscript database

    The additive relationship matrix plays an important role in mixed model prediction of breeding values. For genotype matrix X (loci in columns), the product XX' is widely used as a realized relationship matrix, but the scaling of this matrix is ambiguous. Our first objective was to derive a proper ...

  9. Storage of Renewable Energy by Reduction of CO2 with Hydrogen.

    PubMed

    Züttel, Andreas; Mauron, Philippe; Kato, Shunsuke; Callini, Elsa; Holzer, Marco; Huang, Jianmei

    2015-01-01

    The main difference between the past energy economy during the industrialization period which was mainly based on mining of fossil fuels, e.g. coal, oil and methane and the future energy economy based on renewable energy is the requirement for storage of the energy fluxes. Renewable energy, except biomass, appears in time- and location-dependent energy fluxes as heat or electricity upon conversion. Storage and transport of energy requires a high energy density and has to be realized in a closed materials cycle. The hydrogen cycle, i.e. production of hydrogen from water by renewable energy, storage and use of hydrogen in fuel cells, combustion engines or turbines, is a closed cycle. However, the hydrogen density in a storage system is limited to 20 mass% and 150 kg/m(3) which limits the energy density to about half of the energy density in fossil fuels. Introducing CO(2) into the cycle and storing hydrogen by the reduction of CO(2) to hydrocarbons allows renewable energy to be converted into synthetic fuels with the same energy density as fossil fuels. The resulting cycle is a closed cycle (CO(2) neutral) if CO(2) is extracted from the atmosphere. Today's technology allows CO(2) to be reduced either by the Sabatier reaction to methane, by the reversed water gas shift reaction to CO and further reduction of CO by the Fischer-Tropsch synthesis (FTS) to hydrocarbons or over methanol to gasoline. The overall process can only be realized on a very large scale, because the large number of by-products of FTS requires the use of a refinery. Therefore, a well-controlled reaction to a specific product is required for the efficient conversion of renewable energy (electricity) into an easy to store liquid hydrocarbon (fuel). In order to realize a closed hydrocarbon cycle the two major challenges are to extract CO(2) from the atmosphere close to the thermodynamic limit and to reduce CO(2) with hydrogen in a controlled reaction to a specific hydrocarbon. Nanomaterials with nanopores and the unique surface structures of metallic clusters offer new opportunities for the production of synthetic fuels.

  10. Tunable liquid microlens array driven by pyroelectric effect: full interferometric characterization

    NASA Astrophysics Data System (ADS)

    Miccio, Lisa; Grilli, Simonetta; Vespini, Veronica; Ferraro, Pietro

    2008-09-01

    Liquid lenses with adjustable focal length are of great interest in the field of microfluidic devices. They are, usually, realized by electrowetting effect after electrodes patterning on a hydrofobic substrate. Applications are possible in many fields ranging from commercial products such as digital cameras to biological cell sorting. We realized an open array of liquid lenses with adjustable focal length without electrode patterning. We used a z-cut Lithium Niobate crystal (LN) as substrate and few microliters of an oily substance to obtain the droplets array. The spontaneous polarization of LN crystals is reversed by the electric field poling process, thus enabling the realization of periodically poled LN (PPLN) crystals. The substrate consists of a two-dimensional square array of reversed domains with a period around 200 μm. Each domain presents an hexagonal geometry due to the crystal structure. PPLN is first covered by a thin and homogeneous layer of the above mentioned liquid and therefore its temperature is changed by means of a digitally controlled hot plate. During heating and cooling process there is a rearrangement of the liquid layer until it reaches the final topography. Lenses formation is due to the superficial tension changing at the liquid-solid interface by means of the pyroelectric effect. Such effect allows to create a two-dimensional lens pattern of tunable focal length without electrodes. The temporal evolution of both shape and focal length lenses are quantitatively measured by Digital Holographic Microscopy. Array imaging properties and quantitative analysis of the lenses features and aberrations are presented.

  11. Implementation and image processing of a multi-focusing bionic compound eye

    NASA Astrophysics Data System (ADS)

    Wang, Xin; Guo, Yongcai; Luo, Jiasai

    2018-01-01

    In this paper, a new BCE with multi-focusing microlens array (MLA) was proposed. The BCE consist of detachable micro-hole array (MHA), multi-focusing MLA and spherical substrate, thus allowing it to have a large FOV without crosstalk and stray light. The MHA was fabricated by the precision machining and the parameters of the microlens varied depend on the aperture of micro-hole, through which the implementation of the multi-focusing MLA was realized under the negative pressure. Without the pattern transfer and substrate reshaping, the whole fabrication method was capable of accomplishing within several minutes by using microinjection technology. Furthermore, the method is cost-effective and easy for operation, thus providing a feasible method for the mass production of the BCE. The corresponding image processing was used to realize the image stitching for the sub-image of each single microlens, which offering an integral image in large FOV. The image stitching was implemented through the overlap between the adjacent sub-images and the feature points between the adjacent sub-images were captured by the Harris point detection. By using the adaptive non-maximal suppression, numerous potential mismatching points were eliminated and the algorithm efficiency was proved effectively. Following this, the random sample consensus (RANSAC) was used for feature points matching, by which the relation of projection transformation of the image is obtained. The implementation of the accurate image matching was then realized after the smooth transition by weighted average method. Experimental results indicate that the image-stitching algorithm can be applied for the curved BCE in large field.

  12. New MOEMS based systems appropriate for spectroscopic investigations on agricultural growth and perishable food conditions

    NASA Astrophysics Data System (ADS)

    Grueger, Heinrich; Schenk, Harald; Heberer, Andreas; Zimmer, Fabian; Scherff, Werner; Kenda, Andreas; Frank, Albert

    2005-11-01

    Further optimization of the agricultural growth process and quality control of perishable food which can be fruits and vegetables as well as every kind of meat or milk product requires new approaches for the sensitive front end. One possibility is reflectance or fluorescence spectroscopy in a wide wavelength range. By now broad usage is hindered by costs, size and performance of existing systems. MOEMS scanning gratings for spectrometers and translational mirrors for Fourier Transform spectroscopy enable small robust systems working in a range from 200nm to 5μm. Both types use digital signal processors (DSPs) capable to compute the spectra and execute complex evaluation and decision algorithms. The MOEMS chips are realized by anisotropic etching of a silicon on insulator (SOI) substrate. First the backside silicon and buried oxide is removed by a wet process then the front side structure is realized by dry etching. Depending on the bearing springs a silicon plate up to 3 x 3 mm2 wide and typically 30μm thick can be driven resonantly to rotational or translational movement. Combined with additional optical components and appropriate detectors handheld Czerny-Turner or Fourier Transform spectrometers have been realized and tested. Results of first measurements of reflection spectroscopy on model substances have been performed with both system types in the NIR range. Measurements on real objects like tomatoes or apples are intended for a wider wavelength range. Future systems may contain displays and light sources as well as data storage cards or additional interfaces.

  13. Productivity Sharing Programs: Can They Contribute to Productivity Improvement?

    ERIC Educational Resources Information Center

    General Accounting Office, Washington, DC.

    Productivity sharing plans were studied to determine how they operate, what benefits result, and whether long-term increases in productivity can be realized through the program. Thirty-six firms were interviewed that had productivity sharing plans. Nine firms that had either rejected adoption of a productivity sharing plan or were still…

  14. Impact resistance of metal skin-carbon fiber reinforced polymer laminate structures for the production of lightweight vehicles body frame

    NASA Astrophysics Data System (ADS)

    Quagliato, Luca; Dongwook, Kim; Changsoon, Jang; Naksoo, Kim; Seokmoo, Hong

    2017-05-01

    The research presented in this paper deals, in the first part, with the material characterization of an innovative class of material, made of steel skin and sheet molding compound core, the last one realized with vinyl-ester resin and chopped carbon fibers. Utilizing the results of the material characterization, the case of an automotive B-pillar is taken into account in order to test and prove the reliability of the utilization of this innovative typology of material, instead of the standard steel. The steel skin - SMC hybrid laminate structures are realized by means of stamping process under warm forming condition, in order to favorite the curing of the SMC layers. The result presented along the paper will show that the steel skin - SMC material not only have better specific resistance that those of both standard and high strength steel but also better crashworthiness properties, in comparison to the considered steel. Based on the results of the numerical simulations, a useful way thought which to estimate the crash worthiness property is proposed in this paper and the results will show how the B-pillar realized with steel skin - SMC has a higher impact resistance, in comparison the steel one with the same weight and reduced thickness.

  15. Ultrasonic spray coating polymer and small molecular organic film for organic light-emitting devices.

    PubMed

    Liu, Shihao; Zhang, Xiang; Zhang, Letian; Xie, Wenfa

    2016-11-22

    Ultrasonic spray coating process (USCP) with high material -utilization, low manufacture costs and compatibility to streamline production has been attractive in researches on photoelectric devices. However, surface tension exists in the solvent is still a huge obstacle to realize smooth organic film for organic light emitting devices (OLEDs) by USCP. Here, high quality polymer anode buffer layer and small molecular emitting layer are successfully realized through USCP by introducing extra-low surface tension diluent and surface tension control method. The introduction of low surface tension methyl alcohol is beneficial to the formation of poly (3,4-ethylenedioxythiophene) polystyrene sulfonate (PEDOT:PSS) films and brings obvious phase separation and improved conductivity to PEDOT:PSS film. Besides, a surface tension control method, in which new stable tension equilibrium is built at the border of wetting layer, is proposed to eliminate the effect of surface tension during the solvent evaporation stage of ultrasonic spray coating the film consists of 9,9-Spirobifluoren-2-yl-diphenyl-phosphine oxide doped with 10 wt% tris [2-(p -tolyl) pyridine] iridium (III). A smooth and homogenous small molecular emitting layer without wrinkles is successfully realized. The effectiveness of the ultrasonic spray coating polymer anode buffer layer and small molecular emitting layer are also proved by introducing them in OLEDs.

  16. Ultrasonic spray coating polymer and small molecular organic film for organic light-emitting devices

    NASA Astrophysics Data System (ADS)

    Liu, Shihao; Zhang, Xiang; Zhang, Letian; Xie, Wenfa

    2016-11-01

    Ultrasonic spray coating process (USCP) with high material -utilization, low manufacture costs and compatibility to streamline production has been attractive in researches on photoelectric devices. However, surface tension exists in the solvent is still a huge obstacle to realize smooth organic film for organic light emitting devices (OLEDs) by USCP. Here, high quality polymer anode buffer layer and small molecular emitting layer are successfully realized through USCP by introducing extra-low surface tension diluent and surface tension control method. The introduction of low surface tension methyl alcohol is beneficial to the formation of poly (3,4-ethylenedioxythiophene) polystyrene sulfonate (PEDOT:PSS) films and brings obvious phase separation and improved conductivity to PEDOT:PSS film. Besides, a surface tension control method, in which new stable tension equilibrium is built at the border of wetting layer, is proposed to eliminate the effect of surface tension during the solvent evaporation stage of ultrasonic spray coating the film consists of 9,9-Spirobifluoren-2-yl-diphenyl-phosphine oxide doped with 10 wt% tris [2-(p -tolyl) pyridine] iridium (III). A smooth and homogenous small molecular emitting layer without wrinkles is successfully realized. The effectiveness of the ultrasonic spray coating polymer anode buffer layer and small molecular emitting layer are also proved by introducing them in OLEDs.

  17. Ultrasonic spray coating polymer and small molecular organic film for organic light-emitting devices

    PubMed Central

    Liu, Shihao; Zhang, Xiang; Zhang, Letian; Xie, Wenfa

    2016-01-01

    Ultrasonic spray coating process (USCP) with high material -utilization, low manufacture costs and compatibility to streamline production has been attractive in researches on photoelectric devices. However, surface tension exists in the solvent is still a huge obstacle to realize smooth organic film for organic light emitting devices (OLEDs) by USCP. Here, high quality polymer anode buffer layer and small molecular emitting layer are successfully realized through USCP by introducing extra-low surface tension diluent and surface tension control method. The introduction of low surface tension methyl alcohol is beneficial to the formation of poly (3,4-ethylenedioxythiophene) polystyrene sulfonate (PEDOT:PSS) films and brings obvious phase separation and improved conductivity to PEDOT:PSS film. Besides, a surface tension control method, in which new stable tension equilibrium is built at the border of wetting layer, is proposed to eliminate the effect of surface tension during the solvent evaporation stage of ultrasonic spray coating the film consists of 9,9-Spirobifluoren-2-yl-diphenyl-phosphine oxide doped with 10 wt% tris [2-(p -tolyl) pyridine] iridium (III). A smooth and homogenous small molecular emitting layer without wrinkles is successfully realized. The effectiveness of the ultrasonic spray coating polymer anode buffer layer and small molecular emitting layer are also proved by introducing them in OLEDs. PMID:27874030

  18. Expedient antibiotics production: Final report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bienkowski, P.R.; Byers, C.H.; Lee, D.D.

    The literature on the manufacture, separation and purification, and clinical uses of antibiotics was reviewed, and a bibliography of the pertinent material was completed. Five antimicrobial drugs, penicillin V and G, (and amoxicillin with clavulanic acid), Cephalexin (a cephalosporin), tetracycline and oxytetracycline, Bacitracin (topical), and sulfonamide (chemically produced) were identified for emergency production. Plants that manufacture antibiotics in the continental United States, Mexico, and Puerto Rico have been identified along with potential alternate sites such as those where SCP, enzyme, and fermentation ethanol are produced. Detailed process flow sheets and process descriptions have been derived from the literature and documented.more » This investigation revealed that a typical antibiotic-manufacturing facility is composed of two main sections: (1) a highly specialized, but generic, fermentation unit and (2) a multistep, complex separation and purification unit which is specific to a particular antibiotic product. The fermentation section requires specialized equipment for operation in a sterile environment which is not usually available in other industries. The emergency production of antibiotics under austere conditions will be feasible only if a substantial reduction in the complexity and degree of separation and purity normally required can be realized. Detailed instructions were developed to assist state and federal officials who would be directing the resumption of antibiotic production after a nuclear attack. 182 refs., 54 figs., 26 tabs.« less

  19. Research on photodiode detector-based spatial transient light detection and processing system

    NASA Astrophysics Data System (ADS)

    Liu, Meiying; Wang, Hu; Liu, Yang; Zhao, Hui; Nan, Meng

    2016-10-01

    In order to realize real-time signal identification and processing of spatial transient light, the features and the energy of the captured target light signal are first described and quantitatively calculated. Considering that the transient light signal has random occurrence, a short duration and an evident beginning and ending, a photodiode detector based spatial transient light detection and processing system is proposed and designed in this paper. This system has a large field of view and is used to realize non-imaging energy detection of random, transient and weak point target under complex background of spatial environment. Weak signal extraction under strong background is difficult. In this paper, considering that the background signal changes slowly and the target signal changes quickly, filter is adopted for signal's background subtraction. A variable speed sampling is realized by the way of sampling data points with a gradually increased interval. The two dilemmas that real-time processing of large amount of data and power consumption required by the large amount of data needed to be stored are solved. The test results with self-made simulative signal demonstrate the effectiveness of the design scheme. The practical system could be operated reliably. The detection and processing of the target signal under the strong sunlight background was realized. The results indicate that the system can realize real-time detection of target signal's characteristic waveform and monitor the system working parameters. The prototype design could be used in a variety of engineering applications.

  20. Synthesis of science and art: creating a new domestic world of sensual products

    NASA Astrophysics Data System (ADS)

    Thorpe, Chris; Friend, Clifford M.

    1996-04-01

    The creation of intelligent objects with sensual capabilities and caring personalities; objects which will share our domestic environments and our public spaces, is a vision at once both unnerving and inviting. As research into smart materials, intelligent material systems and the whole spectrum of related areas such as biomimetics, nano-technology and neural systems converge, we are now in a situation where in ten years intelligent objects could realize this lucid projection. The problem comes when we begin to look at the implications of such future object-environments. Our eagerness to solve the complex technical problems associated with the processing and manufacture of smart materials must be placed in the broader context of human considerations. If we are to realize their potential, and optimize the benefits which smart materials and intelligent material systems could bring to our quality of life, we must develop a new approach that is both technologically advanced and sympathetic towards human needs. An approach that is a synthesis of the objective reality sought through science and the irrational, emotional subjectivity embraced in the arts. This paper looks at the design of intelligent objects for the home, examining the role of design, the product interface and the relationship between objects and ourselves within the home environment.

  1. Increasing the efficiency of designing hemming processes by using an element-based metamodel approach

    NASA Astrophysics Data System (ADS)

    Kaiser, C.; Roll, K.; Volk, W.

    2017-09-01

    In the automotive industry, the manufacturing of automotive outer panels requires hemming processes in which two sheet metal parts are joined together by bending the flange of the outer part over the inner part. Because of decreasing development times and the steadily growing number of vehicle derivatives, an efficient digital product and process validation is necessary. Commonly used simulations, which are based on the finite element method, demand significant modelling effort, which results in disadvantages especially in the early product development phase. To increase the efficiency of designing hemming processes this paper presents a hemming-specific metamodel approach. The approach includes a part analysis in which the outline of the automotive outer panels is initially split into individual segments. By doing a para-metrization of each of the segments and assigning basic geometric shapes, the outline of the part is approximated. Based on this, the hemming parameters such as flange length, roll-in, wrinkling and plastic strains are calculated for each of the geometric basic shapes by performing a meta-model-based segmental product validation. The metamodel is based on an element similar formulation that includes a reference dataset of various geometric basic shapes. A random automotive outer panel can now be analysed and optimized based on the hemming-specific database. By implementing this approach into a planning system, an efficient optimization of designing hemming processes will be enabled. Furthermore, valuable time and cost benefits can be realized in a vehicle’s development process.

  2. A novel cell factory for efficient production of ethanol from dairy waste.

    PubMed

    Liu, Jianming; Dantoft, Shruti Harnal; Würtz, Anders; Jensen, Peter Ruhdal; Solem, Christian

    2016-01-01

    Sustainable and economically feasible ways to produce ethanol or other liquid fuels are becoming increasingly relevant due to the limited supply of fossil fuels and the environmental consequences associated with their consumption. Microbial production of fuel compounds has gained a lot of attention and focus has mostly been on developing bio-processes involving non-food plant biomass feedstocks. The high cost of the enzymes needed to degrade such feedstocks into its constituent sugars as well as problems due to various inhibitors generated in pretreatment are two challenges that have to be addressed if cost-effective processes are to be established. Various industries, especially within the food sector, often have waste streams rich in carbohydrates and/or other nutrients, and these could serve as alternative feedstocks for such bio-processes. The dairy industry is a good example, where large amounts of cheese whey or various processed forms thereof are generated. Because of their nutrient-rich nature, these substrates are particularly well suited as feedstocks for microbial production. We have generated a Lactococcus lactis strain which produces ethanol as its sole fermentation product from the lactose contained in residual whey permeate (RWP), by introducing lactose catabolism into a L. lactis strain CS4435 (MG1363 Δ(3) ldh, Δpta, ΔadhE, pCS4268), where the carbon flow has been directed toward ethanol instead of lactate. To achieve growth and ethanol production on RWP, we added corn steep liquor hydrolysate (CSLH) as the nitrogen source. The outcome was efficient ethanol production with a titer of 41 g/L and a yield of 70 % of the theoretical maximum using a fed-batch strategy. The combination of a low-cost medium from industrial waste streams and an efficient cell factory should make the developed process industrially interesting. A process for the production of ethanol using L. lactis and a cheap renewable feedstock was developed. The results demonstrate that it is possible to achieve sustainable bioconversion of waste products from the dairy industry (RWP) and corn milling industry (CSLH) to ethanol and the process developed shows great potential for commercial realization.

  3. [A strategy of constructing the technological system for quality control of Chinese medicine based on process control and management].

    PubMed

    Cheng, Yi-Yu; Qian, Zhong-Zhi; Zhang, Bo-Li

    2017-01-01

    The current situation, bottleneck problems and severe challenges in quality control technology of Chinese Medicine (CM) are briefly described. It is presented to change the phenomenon related to the post-test as the main means and contempt for process control in drug regulation, reverse the situation of neglecting the development of process control and management technology for pharmaceutical manufacture and reconstruct the technological system for quality control of CM products. The regulation and technology system based on process control and management for controlling CM quality should be established to solve weighty realistic problems of CM industry from the root causes, including backwardness of quality control technology, weakness of quality risk control measures, poor reputation of product quality and so on. By this way, the obstacles from poor controllability of CM product quality could be broken. Concentrating on those difficult problems and weak links in the technical field of CM quality control, it is proposed to build CMC (Chemistry, Manufacturing and Controls) regulation for CM products with Chinese characteristics and promote the regulation international recognition as soon as possible. The CMC technical framework, which is clinical efficacy-oriented, manufacturing manner-centered and process control-focused, was designed. To address the clinical characteristics of traditional Chinese medicine (TCM) and the production feature of CM manufacture, it is suggested to establish quality control engineering for CM manufacturing by integrating pharmaceutical analysis, TCM chemistry, TCM pharmacology, pharmaceutical engineering, control engineering, management engineering and other disciplines. Further, a theoretical model of quality control engineering for CM manufacturing and the methodology of digital pharmaceutical engineering are proposed. A technology pathway for promoting CM standard and realizing the strategic goal of CM internationalization is elaborated. Copyright© by the Chinese Pharmaceutical Association.

  4. Process-based Cost Estimation for Ramjet/Scramjet Engines

    NASA Technical Reports Server (NTRS)

    Singh, Brijendra; Torres, Felix; Nesman, Miles; Reynolds, John

    2003-01-01

    Process-based cost estimation plays a key role in effecting cultural change that integrates distributed science, technology and engineering teams to rapidly create innovative and affordable products. Working together, NASA Glenn Research Center and Boeing Canoga Park have developed a methodology of process-based cost estimation bridging the methodologies of high-level parametric models and detailed bottoms-up estimation. The NASA GRC/Boeing CP process-based cost model provides a probabilistic structure of layered cost drivers. High-level inputs characterize mission requirements, system performance, and relevant economic factors. Design alternatives are extracted from a standard, product-specific work breakdown structure to pre-load lower-level cost driver inputs and generate the cost-risk analysis. As product design progresses and matures the lower level more detailed cost drivers can be re-accessed and the projected variation of input values narrowed, thereby generating a progressively more accurate estimate of cost-risk. Incorporated into the process-based cost model are techniques for decision analysis, specifically, the analytic hierarchy process (AHP) and functional utility analysis. Design alternatives may then be evaluated not just on cost-risk, but also user defined performance and schedule criteria. This implementation of full-trade study support contributes significantly to the realization of the integrated development environment. The process-based cost estimation model generates development and manufacturing cost estimates. The development team plans to expand the manufacturing process base from approximately 80 manufacturing processes to over 250 processes. Operation and support cost modeling is also envisioned. Process-based estimation considers the materials, resources, and processes in establishing cost-risk and rather depending on weight as an input, actually estimates weight along with cost and schedule.

  5. Evaluating realized genetic gains from tree improvement.

    Treesearch

    J.B. St. Clair

    1993-01-01

    Tree improvement has become an essential part of the management of forest lands for wood production, and predicting yields and realized gains from forests planted with genetically-improved trees will become increasingly important. This paper discusses concepts of tree improvement and genetic gain important to growth and yield modeling, and reviews previous studies of...

  6. CO 2 Sequestration and Enhanced Oil Recovery at Depleted Oil/Gas Reservoirs

    DOE PAGES

    Dai, Zhenxue; Viswanathan, Hari; Xiao, Ting; ...

    2017-08-18

    This study presents a quantitative evaluation of the operational and technical risks of an active CO 2-EOR project. A set of risk factor metrics is defined to post-process the Monte Carlo (MC) simulations for statistical analysis. The risk factors are expressed as measurable quantities that can be used to gain insight into project risk (e.g. environmental and economic risks) without the need to generate a rigorous consequence structure, which include (a) CO 2 injection rate, (b) net CO 2 injection rate, (c) cumulative CO 2 storage, (d) cumulative water injection, (e) oil production rate, (f) cumulative oil production, (g) cumulativemore » CH 4 production, and (h) CO 2 breakthrough time. The Morrow reservoir at the Farnsworth Unit (FWU) site, Texas, is used as an example for studying the multi-scale statistical approach for CO 2 accounting and risk analysis. A set of geostatistical-based MC simulations of CO 2-oil/gas-water flow and transport in the Morrow formation are conducted for evaluating the risk metrics. A response-surface-based economic model has been derived to calculate the CO 2-EOR profitability for the FWU site with a current oil price, which suggests that approximately 31% of the 1000 realizations can be profitable. If government carbon-tax credits are available, or the oil price goes up or CO 2 capture and operating expenses reduce, more realizations would be profitable.« less

  7. CO 2 Sequestration and Enhanced Oil Recovery at Depleted Oil/Gas Reservoirs

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Dai, Zhenxue; Viswanathan, Hari; Xiao, Ting

    This study presents a quantitative evaluation of the operational and technical risks of an active CO 2-EOR project. A set of risk factor metrics is defined to post-process the Monte Carlo (MC) simulations for statistical analysis. The risk factors are expressed as measurable quantities that can be used to gain insight into project risk (e.g. environmental and economic risks) without the need to generate a rigorous consequence structure, which include (a) CO 2 injection rate, (b) net CO 2 injection rate, (c) cumulative CO 2 storage, (d) cumulative water injection, (e) oil production rate, (f) cumulative oil production, (g) cumulativemore » CH 4 production, and (h) CO 2 breakthrough time. The Morrow reservoir at the Farnsworth Unit (FWU) site, Texas, is used as an example for studying the multi-scale statistical approach for CO 2 accounting and risk analysis. A set of geostatistical-based MC simulations of CO 2-oil/gas-water flow and transport in the Morrow formation are conducted for evaluating the risk metrics. A response-surface-based economic model has been derived to calculate the CO 2-EOR profitability for the FWU site with a current oil price, which suggests that approximately 31% of the 1000 realizations can be profitable. If government carbon-tax credits are available, or the oil price goes up or CO 2 capture and operating expenses reduce, more realizations would be profitable.« less

  8. Accurate Micro-Tool Manufacturing by Iterative Pulsed-Laser Ablation

    NASA Astrophysics Data System (ADS)

    Warhanek, Maximilian; Mayr, Josef; Dörig, Christian; Wegener, Konrad

    2017-12-01

    Iterative processing solutions, including multiple cycles of material removal and measurement, are capable of achieving higher geometric accuracy by compensating for most deviations manifesting directly on the workpiece. Remaining error sources are the measurement uncertainty and the repeatability of the material-removal process including clamping errors. Due to the lack of processing forces, process fluids and wear, pulsed-laser ablation has proven high repeatability and can be realized directly on a measuring machine. This work takes advantage of this possibility by implementing an iterative, laser-based correction process for profile deviations registered directly on an optical measurement machine. This way efficient iterative processing is enabled, which is precise, applicable for all tool materials including diamond and eliminates clamping errors. The concept is proven by a prototypical implementation on an industrial tool measurement machine and a nanosecond fibre laser. A number of measurements are performed on both the machine and the processed workpieces. Results show production deviations within 2 μm diameter tolerance.

  9. Optimization of the production process using virtual model of a workspace

    NASA Astrophysics Data System (ADS)

    Monica, Z.

    2015-11-01

    Optimization of the production process is an element of the design cycle consisting of: problem definition, modelling, simulation, optimization and implementation. Without the use of simulation techniques, the only thing which could be achieved is larger or smaller improvement of the process, not the optimization (i.e., the best result it is possible to get for the conditions under which the process works). Optimization is generally management actions that are ultimately bring savings in time, resources, and raw materials and improve the performance of a specific process. It does not matter whether it is a service or manufacturing process. Optimizing the savings generated by improving and increasing the efficiency of the processes. Optimization consists primarily of organizational activities that require very little investment, or rely solely on the changing organization of work. Modern companies operating in a market economy shows a significant increase in interest in modern methods of production management and services. This trend is due to the high competitiveness among companies that want to achieve success are forced to continually modify the ways to manage and flexible response to changing demand. Modern methods of production management, not only imply a stable position of the company in the sector, but also influence the improvement of health and safety within the company and contribute to the implementation of more efficient rules for standardization work in the company. This is why in the paper is presented the application of such developed environment like Siemens NX to create the virtual model of a production system and to simulate as well as optimize its work. The analyzed system is the robotized workcell consisting of: machine tools, industrial robots, conveyors, auxiliary equipment and buffers. In the program could be defined the control program realizing the main task in the virtual workcell. It is possible, using this tool, to optimize both the object trajectory and the cooperation process.

  10. From Safe Nanomanufacturing to Nanosafe-by-Design processes

    NASA Astrophysics Data System (ADS)

    Schuster, F.; Lomello, F.

    2013-04-01

    Industrial needs in terms of multifunctional components are increasing. Many sectors are concerned, from the integrated direct nanoparticles production to the emerging combinations which include the metal matrix composites (MMC), ductile ceramics and ceramic matrix composites, polymer matrix composites (PMC) for bulk application and advanced surface coatings in the fields of automotive, aerospace, energy production and building applications. Moreover, domains with a planetary impact such as environmental issues, as well as aspects for instance health (toxicity) and hazard assessment (ignition and explosion severity) were also taken into account. Nanotechnologies play an important role in promoting innovation in design and realization of multifunctional products for the future, either by improving usual products or creating new functions and/or new products. Nevertheless, this huge evolution in terms of materials could only be promoted by increasing the social acceptance and by acting on the different main technological and economic challenges and developing safe oriented processes. Nowadays, a huge number of developments of nanoparticles are potentially industrial up-scalable. However, some doubts exist about the handling's safety of the current technologies. For these reasons, the main purpose was to develop a self-monitored automation in the production line coupling different techniques in order to simplify processes such as in-situ growth nanoparticles into a nanostructured matrix, over different substrates and/or the nanopowders synthesis, functionalization, dry or wet safe recovery system, granulation, consolidation in single-step, by monitoring at real time the processing parameters such as powder stoichiometry. With the aim of assuring the traceability of the product during the whole life, starting from the conception and including the R&D, the distribution and the use were also considered. The optimization in terms of processing, recovery and conditioning, permits to increase its versatility, thus leading to the increase of the added value to the production. This review put in evidence -by different examples- the progress achieved since the beginning of Nanosafe integrated initiative developed by CEA and its partners as well as promoting, firstly the safety at work place, and then extending to an integrated and controlled in-situ production by of Nanosafe-by-Design controlled processes.

  11. Carbon-free hydrogen production from low rank coal

    NASA Astrophysics Data System (ADS)

    Aziz, Muhammad; Oda, Takuya; Kashiwagi, Takao

    2018-02-01

    Novel carbon-free integrated system of hydrogen production and storage from low rank coal is proposed and evaluated. To measure the optimum energy efficiency, two different systems employing different chemical looping technologies are modeled. The first integrated system consists of coal drying, gasification, syngas chemical looping, and hydrogenation. On the other hand, the second system combines coal drying, coal direct chemical looping, and hydrogenation. In addition, in order to cover the consumed electricity and recover the energy, combined cycle is adopted as addition module for power generation. The objective of the study is to find the best system having the highest performance in terms of total energy efficiency, including hydrogen production efficiency and power generation efficiency. To achieve a thorough energy/heat circulation throughout each module and the whole integrated system, enhanced process integration technology is employed. It basically incorporates two core basic technologies: exergy recovery and process integration. Several operating parameters including target moisture content in drying module, operating pressure in chemical looping module, are observed in terms of their influence to energy efficiency. From process modeling and calculation, two integrated systems can realize high total energy efficiency, higher than 60%. However, the system employing coal direct chemical looping represents higher energy efficiency, including hydrogen production and power generation, which is about 83%. In addition, optimum target moisture content in drying and operating pressure in chemical looping also have been defined.

  12. Immersion lithography defectivity analysis at DUV inspection wavelength

    NASA Astrophysics Data System (ADS)

    Golan, E.; Meshulach, D.; Raccah, N.; Yeo, J. Ho.; Dassa, O.; Brandl, S.; Schwarz, C.; Pierson, B.; Montgomery, W.

    2007-03-01

    Significant effort has been directed in recent years towards the realization of immersion lithography at 193nm wavelength. Immersion lithography is likely a key enabling technology for the production of critical layers for 45nm and 32nm design rule (DR) devices. In spite of the significant progress in immersion lithography technology, there remain several key technology issues, with a critical issue of immersion lithography process induced defects. The benefits of the optical resolution and depth of focus, made possible by immersion lithography, are well understood. Yet, these benefits cannot come at the expense of increased defect counts and decreased production yield. Understanding the impact of the immersion lithography process parameters on wafer defects formation and defect counts, together with the ability to monitor, control and minimize the defect counts down to acceptable levels is imperative for successful introduction of immersion lithography for production of advanced DR's. In this report, we present experimental results of immersion lithography defectivity analysis focused on topcoat layer thickness parameters and resist bake temperatures. Wafers were exposed on the 1150i-α-immersion scanner and 1200B Scanner (ASML), defect inspection was performed using a DUV inspection tool (UVision TM, Applied Materials). Higher sensitivity was demonstrated at DUV through detection of small defects not detected at the visible wavelength, indicating on the potential high sensitivity benefits of DUV inspection for this layer. The analysis indicates that certain types of defects are associated with different immersion process parameters. This type of analysis at DUV wavelengths would enable the optimization of immersion lithography processes, thus enabling the qualification of immersion processes for volume production.

  13. Spatial decision support system for tobacco enterprise based on spatial data mining

    NASA Astrophysics Data System (ADS)

    Mei, Xin; Liu, Junyi; Zhang, Xuexia; Cui, Weihong

    2007-11-01

    Tobacco enterprise is a special enterprise, which has strong correlation to regional geography. But in the past research and application, the combination between tobacco and GIS is limited to use digital maps to assist cigarette distribution. How to comprehensively import 3S technique and spatial data mining (SDM) to construct spatial decision support system (SDSS) of tobacco enterprise is the main research aspect in this paper. The paper concretely analyzes the GIS requirements in tobacco enterprise for planning location of production, monitoring production management and product sale at the beginning. Then holistic solution is presented and frame design for tobacco enterprise spatial decision based on SDM is given. This paper describes how to use spatial analysis and data mining to realize the spatial decision processing such as monitoring tobacco planted acreage, analyzing and planning the cigarette sale network and so on.

  14. [Establishment of traceability system of Chinese medicinal materials' quality].

    PubMed

    Qi, Yao-dong; Gao, Shi-man; Liu, Hai-tao; Li, Xi-wen; Wei, Jian-he; Zhang, Ben-gang; Sun, Xiao-bo; Xiao, Pei-gen

    2015-12-01

    The quality of Chinese medicinal materials relates greatly to the clinical curative effect and security. In order to ensure the quality and safety of Chinese medicinal materials, a systematic and operable traceability system needs to be established. It can realize the whole process of quality and safety management of Chinese medicinal materials "from production to consumption" through recording and inquiring information and recalling defective products, which is an important direction for the future development of traditional Chinese medicine. But it is still at the exploration and trial stage. In this paper, a framework of Chinese medicinal materials' quality and safety traceability system was established on the basis of the domestic and international experience about the construction of food and agricultural products traceability systems. The relationship between traceability system of Chinese medicinal materials' quality and GAP, GMP, GSP was analyzed, and the possible problems and the corresponding solutions were discussed.

  15. Joule-Heated Molten Regolith Electrolysis Reactor Concepts for Oxygen and Metals Production on the Moon and Mars

    NASA Technical Reports Server (NTRS)

    Sibille, Laurent; Dominques, Jesus A.

    2012-01-01

    The maturation of Molten Regolith Electrolysis (MRE) as a viable technology for oxygen and metals production on explored planets relies on the realization of the self-heating mode for the reactor. Joule heat generated during regolith electrolysis creates thermal energy that should be able to maintain the molten phase (similar to electrolytic Hall-Heroult process for aluminum production). Self-heating via Joule heating offers many advantages: (1) The regolith itself is the crucible material, it protects the vessel walls (2) Simplifies the engineering of the reactor (3) Reduces power consumption (no external heating) (4) Extends the longevity of the reactor. Predictive modeling is a tool chosen to perform dimensional analysis of a self-heating reactor: (1) Multiphysics modeling (COMSOL) was selected for Joule heat generation and heat transfer (2) Objective is to identify critical dimensions for first reactor prototype.

  16. Predicting fundamental and realized distributions based on thermal niche: A case study of a freshwater turtle

    NASA Astrophysics Data System (ADS)

    Rodrigues, João Fabrício Mota; Coelho, Marco Túlio Pacheco; Ribeiro, Bruno R.

    2018-04-01

    Species distribution models (SDM) have been broadly used in ecology to address theoretical and practical problems. Currently, there are two main approaches to generate SDMs: (i) correlative, which is based on species occurrences and environmental predictor layers and (ii) process-based models, which are constructed based on species' functional traits and physiological tolerances. The distributions estimated by each approach are based on different components of species niche. Predictions of correlative models approach species realized niches, while predictions of process-based are more akin to species fundamental niche. Here, we integrated the predictions of fundamental and realized distributions of the freshwater turtle Trachemys dorbigni. Fundamental distribution was estimated using data of T. dorbigni's egg incubation temperature, and realized distribution was estimated using species occurrence records. Both types of distributions were estimated using the same regression approaches (logistic regression and support vector machines), both considering macroclimatic and microclimatic temperatures. The realized distribution of T. dorbigni was generally nested in its fundamental distribution reinforcing theoretical assumptions that the species' realized niche is a subset of its fundamental niche. Both modelling algorithms produced similar results but microtemperature generated better results than macrotemperature for the incubation model. Finally, our results reinforce the conclusion that species realized distributions are constrained by other factors other than just thermal tolerances.

  17. Design of video processing and testing system based on DSP and FPGA

    NASA Astrophysics Data System (ADS)

    Xu, Hong; Lv, Jun; Chen, Xi'ai; Gong, Xuexia; Yang, Chen'na

    2007-12-01

    Based on high speed Digital Signal Processor (DSP) and Field Programmable Gate Array (FPGA), a video capture, processing and display system is presented, which is of miniaturization and low power. In this system, a triple buffering scheme was used for the capture and display, so that the application can always get a new buffer without waiting; The Digital Signal Processor has an image process ability and it can be used to test the boundary of workpiece's image. A video graduation technology is used to aim at the position which is about to be tested, also, it can enhance the system's flexibility. The character superposition technology realized by DSP is used to display the test result on the screen in character format. This system can process image information in real time, ensure test precision, and help to enhance product quality and quality management.

  18. Ultrarapid Multimode Microwave Synthesis of Nano/Submicron β-SiC

    PubMed Central

    Johnson, Michael; He, Wenzhi; Li, Guangming; Zhao, Chen; Yu, Luling; Huang, Juwen; Zhu, Haochen

    2018-01-01

    This paper presents the design, development and realization of a fast and novel process for the synthesis of 3C silicon carbide (β-SiC) nanorods and submicron powder. Using SiO2 (or Si) and activated carbon (AC), this process allows β-SiC to be synthesized with almost 100% purity in timeframes of seconds or minutes using multimode microwave rotary tube reactors under open-air conditions. The synthesis temperature used was 1460 ± 50 °C for Si + AC and 1660 ± 50 °C for SiO2 + AC. The shortest β-SiC synthesis time achieved was about 20 s for Si + AC and 100 s for SiO2 + AC. This novel synthesis method allows for scaled-up flow processes in the rapid industrial-scale production of β-SiC, having advantages of time/energy saving and carbon dioxide emission reduction over comparable modern processes. PMID:29470417

  19. Novel organic LED structures based on a highly conductive polymeric photonic crystal electrode.

    PubMed

    Petti, Lucia; Rippa, Massimo; Capasso, Rossella; Nenna, Giuseppe; Del Mauro, Anna De Girolamo; Maglione, Maria Grazia; Minarini, Carla

    2013-08-09

    In this work we demonstrate the possibility to realize a novel unconventional ITO-free organic light emitting diode (OLED) utilizing a photonic polymeric electrode. Combining electron beam lithography and a plasma etching process to partially structure the highly conductive poly(3,4 ethylenedioxythiophene):poly(styrene sulfonate) (PEDOT:PSS) it is possible to realize an embedded photonic crystal (PC) structure. The realized PC-anode drastically reduces the light trapped in the OLED, demonstrating the possibility to eliminate further process stages and making it easier to use this technology even on rollable and flexible substrates.

  20. Novel organic LED structures based on a highly conductive polymeric photonic crystal electrode

    NASA Astrophysics Data System (ADS)

    Petti, Lucia; Rippa, Massimo; Capasso, Rossella; Nenna, Giuseppe; De Girolamo Del Mauro, Anna; Grazia Maglione, Maria; Minarini, Carla

    2013-08-01

    In this work we demonstrate the possibility to realize a novel unconventional ITO-free organic light emitting diode (OLED) utilizing a photonic polymeric electrode. Combining electron beam lithography and a plasma etching process to partially structure the highly conductive poly(3,4 ethylenedioxythiophene):poly(styrene sulfonate) (PEDOT:PSS) it is possible to realize an embedded photonic crystal (PC) structure. The realized PC-anode drastically reduces the light trapped in the OLED, demonstrating the possibility to eliminate further process stages and making it easier to use this technology even on rollable and flexible substrates.

  1. Three-dimensional plotting and printing of an implant drilling guide: simplifying guided implant surgery.

    PubMed

    Flügge, Tabea Viktoria; Nelson, Katja; Schmelzeisen, Rainer; Metzger, Marc Christian

    2013-08-01

    To present an efficient workflow for the production of implant drilling guides using virtual planning tools. For this purpose, laser surface scanning, cone beam computed tomography, computer-aided design and manufacturing, and 3-dimensional (3D) printing were combined. Intraoral optical impressions (iTero, Align Technologies, Santa Clara, CA) and digital 3D radiographs (cone beam computed tomography) were performed at the first consultation of 1 exemplary patient. With image processing techniques, the intraoral surface data, acquired using an intraoral scanner, and radiologic 3D data were fused. The virtual implant planning process (using virtual library teeth) and the in-office production of the implant drilling guide was performed after only 1 clinical consultation of the patient. Implant surgery with a computer-aided design and manufacturing produced implant drilling guide was performed during the second consultation. The production of a scan prosthesis and multiple preoperative consultations of the patient were unnecessary. The presented procedure offers another step in facilitating the production of drilling guides in dental implantology. Four main advantages are realized with this procedure. First, no additional scan prosthesis is needed. Second, data acquisition can be performed during the first consultation. Third, the virtual planning is directly transferred to the drilling guide without a loss of accuracy. Finally, the treatment cost and time required are reduced with this facilitated production process. Copyright © 2013 American Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc. All rights reserved.

  2. Probing new charged scalars with neutrino trident production

    NASA Astrophysics Data System (ADS)

    Magill, Gabriel; Plestid, Ryan

    2018-03-01

    We investigate the possibility of using neutrino trident production to probe leptophilic charged scalars at future high intensity neutrino experiments. We show that under specific assumptions, this production process can provide competitive sensitivity for generic charged scalars as compared to common existing bounds. We also investigate how the recently proposed mixed-flavor production—where the two oppositely charged leptons in the final state need not be muon flavored—can give a 20%-50% increase in sensitivity for certain configurations of new physics couplings as compared to traditional trident modes. We then categorize all renormalizable leptophilic scalar extensions based on their representation under SU (2 )×U (1 ), and discuss the Higgs triplet and Zee-Babu models as explicit UV realizations. We find that the inclusion of additional doubly charged scalars and the need to reproduce neutrino masses make trident production uncompetitive with current bounds for these specific UV completions. Our work represents the first application of neutrino trident production to study charged scalars. Additionally, it is the first application of mixed-flavor trident production to study physics beyond the standard model more generally.

  3. An Intelligent Automation Platform for Rapid Bioprocess Design.

    PubMed

    Wu, Tianyi; Zhou, Yuhong

    2014-08-01

    Bioprocess development is very labor intensive, requiring many experiments to characterize each unit operation in the process sequence to achieve product safety and process efficiency. Recent advances in microscale biochemical engineering have led to automated experimentation. A process design workflow is implemented sequentially in which (1) a liquid-handling system performs high-throughput wet lab experiments, (2) standalone analysis devices detect the data, and (3) specific software is used for data analysis and experiment design given the user's inputs. We report an intelligent automation platform that integrates these three activities to enhance the efficiency of such a workflow. A multiagent intelligent architecture has been developed incorporating agent communication to perform the tasks automatically. The key contribution of this work is the automation of data analysis and experiment design and also the ability to generate scripts to run the experiments automatically, allowing the elimination of human involvement. A first-generation prototype has been established and demonstrated through lysozyme precipitation process design. All procedures in the case study have been fully automated through an intelligent automation platform. The realization of automated data analysis and experiment design, and automated script programming for experimental procedures has the potential to increase lab productivity. © 2013 Society for Laboratory Automation and Screening.

  4. Automating expert role to determine design concept in Kansei Engineering

    NASA Astrophysics Data System (ADS)

    Lokman, Anitawati Mohd; Haron, Mohammad Bakri Che; Abidin, Siti Zaleha Zainal; Khalid, Noor Elaiza Abd

    2016-02-01

    Affect has become imperative in product quality. In affective design field, Kansei Engineering (KE) has been recognized as a technology that enables discovery of consumer's emotion and formulation of guide to design products that win consumers in the competitive market. Albeit powerful technology, there is no rule of thumb in its analysis and interpretation process. KE expertise is required to determine sets of related Kansei and the significant concept of emotion. Many research endeavors become handicapped with the limited number of available and accessible KE experts. This work is performed to simulate the role of experts with the use of Natphoric algorithm thus providing sound solution to the complexity and flexibility in KE. The algorithm is designed to learn the process by implementing training datasets taken from previous KE research works. A framework for automated KE is then designed to realize the development of automated KE system. A comparative analysis is performed to determine feasibility of the developed prototype to automate the process. The result shows that the significant Kansei is determined by manual KE implementation and the automated process is highly similar. KE research advocates will benefit this system to automatically determine significant design concepts.

  5. An Intelligent Automation Platform for Rapid Bioprocess Design

    PubMed Central

    Wu, Tianyi

    2014-01-01

    Bioprocess development is very labor intensive, requiring many experiments to characterize each unit operation in the process sequence to achieve product safety and process efficiency. Recent advances in microscale biochemical engineering have led to automated experimentation. A process design workflow is implemented sequentially in which (1) a liquid-handling system performs high-throughput wet lab experiments, (2) standalone analysis devices detect the data, and (3) specific software is used for data analysis and experiment design given the user’s inputs. We report an intelligent automation platform that integrates these three activities to enhance the efficiency of such a workflow. A multiagent intelligent architecture has been developed incorporating agent communication to perform the tasks automatically. The key contribution of this work is the automation of data analysis and experiment design and also the ability to generate scripts to run the experiments automatically, allowing the elimination of human involvement. A first-generation prototype has been established and demonstrated through lysozyme precipitation process design. All procedures in the case study have been fully automated through an intelligent automation platform. The realization of automated data analysis and experiment design, and automated script programming for experimental procedures has the potential to increase lab productivity. PMID:24088579

  6. Software Process Assessment (SPA)

    NASA Technical Reports Server (NTRS)

    Rosenberg, Linda H.; Sheppard, Sylvia B.; Butler, Scott A.

    1994-01-01

    NASA's environment mirrors the changes taking place in the nation at large, i.e. workers are being asked to do more work with fewer resources. For software developers at NASA's Goddard Space Flight Center (GSFC), the effects of this change are that we must continue to produce quality code that is maintainable and reusable, but we must learn to produce it more efficiently and less expensively. To accomplish this goal, the Data Systems Technology Division (DSTD) at GSFC is trying a variety of both proven and state-of-the-art techniques for software development (e.g., object-oriented design, prototyping, designing for reuse, etc.). In order to evaluate the effectiveness of these techniques, the Software Process Assessment (SPA) program was initiated. SPA was begun under the assumption that the effects of different software development processes, techniques, and tools, on the resulting product must be evaluated in an objective manner in order to assess any benefits that may have accrued. SPA involves the collection and analysis of software product and process data. These data include metrics such as effort, code changes, size, complexity, and code readability. This paper describes the SPA data collection and analysis methodology and presents examples of benefits realized thus far by DSTD's software developers and managers.

  7. Reduced graphene oxide-induced recrystallization of NiS nanorods to nanosheets and the improved Na-storage properties.

    PubMed

    Pan, Qin; Xie, Jian; Zhu, Tiejun; Cao, Gaoshao; Zhao, Xinbing; Zhang, Shichao

    2014-04-07

    Preparation of two-dimensional (2D) graphene-like materials is currently an emerging field in materials science since the discovery of single-atom-thick graphene prepared by mechanical cleavage. In this work, we proposed a new method to prepare 2D NiS, where reduced graphene oxide (rGO) was found to induce the recrystallization of NiS from nanorods to nanosheets in a hydrothermal process. The process and mechanism of recrystallization have been clarified by various characterization techniques, including scanning electron microscopy (SEM), transmission electron microscopy (TEM), energy dispersive X-ray spectroscopy (EDS) mapping, and X-ray photoelectron spectroscopy (XPS). The characterization of ex situ NiS/rGO products by SEM and EDS mapping indicates that the recrystallization of NiS from nanorods to nanosheets is realized actually through an exfoliation process, while the characterization of in situ NiS/rGO products by SEM, TEM, and EDS mapping reveals the exfoliation process. The XPS result demonstrates that hydrothermally assisted chemical bonding occurs between NiS and rGO, which induces the exfoliation of NiS nanorods into nanosheets. The obtained NiS/rGO composite shows promising Na-storage properties.

  8. Insect mass production technologies

    USDA-ARS?s Scientific Manuscript database

    Insects provide a very promising alternative for the future production of animal protein. Their nutritional value in conjunction with their food conversion efficiency and low water requirements, make them a more sustainable choice for the production of food and animal origin. However, to realize the...

  9. Inflationary preheating dynamics with two-species condensates

    NASA Astrophysics Data System (ADS)

    Zache, T. V.; Kasper, V.; Berges, J.

    2017-06-01

    We investigate both analytically and numerically a two-component ultracold atom system in one spatial dimension. The model features a tachyonic instability, which incorporates characteristic aspects of the mechanisms for particle production in early universe inflaton models. We establish a direct correspondence between measurable macroscopic growth rates for occupation numbers of the ultracold Bose gas and the underlying microscopic processes in terms of Feynman loop diagrams. We analyze several existing ultracold atom setups featuring dynamical instabilities and propose optimized protocols for their experimental realization. We demonstrate that relevant dynamical processes can be enhanced using a seeding procedure for unstable modes and clarify the role of initial quantum fluctuations and the generation of a nonlinear secondary stage for the amplification of modes.

  10. The Sensor Management for Applied Research Technologies (SMART) Project

    NASA Technical Reports Server (NTRS)

    Goodman, Michael; Jedlovec, Gary; Conover, Helen; Botts, Mike; Robin, Alex; Blakeslee, Richard; Hood, Robbie; Ingenthron, Susan; Li, Xiang; Maskey, Manil; hide

    2007-01-01

    NASA seeks on-demand data processing and analysis of Earth science observations to facilitate timely decision-making that can lead to the realization of the practical benefits of satellite instruments, airborne and surface remote sensing systems. However, a significant challenge exists in accessing and integrating data from multiple sensors or platforms to address Earth science problems because of the large data volumes, varying sensor scan characteristics, unique orbital coverage, and the steep "learning curve" associated with each sensor, data type, and associated products. The development of sensor web capabilities to autonomously process these data streams (whether real-time or archived) provides an opportunity to overcome these obstacles and facilitate the integration and synthesis of Earth science data and weather model output.

  11. Systems Engineering Awareness

    NASA Technical Reports Server (NTRS)

    Lucero, John

    2016-01-01

    The presentation will provide an overview of the fundamentals and principles of Systems Engineering (SE). This includes understanding the processes that are used to assist the engineer in a successful design, build and implementation of solutions. The context of this presentation will be to describe the involvement of SE throughout the life-cycle of a project from cradle to grave. Due to the ever growing number of complex technical problems facing our world, a Systems Engineering approach is desirable for many reasons. The interdisciplinary technical structure of current systems, technical processes representing System Design, Technical Management and Product Realization are instrumental in the development and integration of new technologies into mainstream applications. This tutorial will demonstrate the application of SE tools to these types of problems..

  12. Pilot-plant studies of the pipe- and pipe-cross reactors in production of granular polyphosphate fertilizers. TVA Circular Z-148. [Methods of increasing polyphosphate content of suspension fertilizers

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Parker, B.R.; Norton, M.M.; Stumpe, T.R.

    1982-01-01

    Improvements have been made in the pipe-reactor or pipe-cross reactor/drum-granulator process to increase the polyphosphate content of the granular product. The goal of producing a granular APP product containing 20% of P/sub 2/O/sub 5/ as polyphosphate without adding external heat or sulfuric acid to the process has not yet been realized; however, products containing slightly more than 10% of the P/sub 2/O/sub 5/ as polyphosphate have been made without the need for external heat. Test results indicate that additions of small amounts of sulfuric acid, use of reactant NH/sub 3/:H/sub 3/PO/sub 4/ed mole ratios greater than 1.05, or use ofmore » some acid preheat may be required to consistently obtain 12% of the P/sub 2/O/sub 5/ as polyphosphate as is desired for use of the product in the preparation of suspension fertilizers. However, continued testing is being done to determine how high a mole ratio may be used successfully and to determine the effect of sulfate addition on use of the granular products for producing suspension fertilizers. The effort to obtain higher polyphosphate levels from the pipe-reactor and drum and the pipe-cross reactor and drum systems is being continued.« less

  13. The Next Generation of Magnesium Based Material to Sustain the Intergovernmental Panel on Climate Change Policy

    NASA Astrophysics Data System (ADS)

    D'Errico, F.; Farè, S.; Garces, G.

    Current Mg alloys have several drawbacks that limit wide and profitable utilization in the industrial sector. From an environmental point of view, lighter metals like magnesium are currently considered unclean products as they require energy-intensive. But they have been proven to be "clean" in the transport sector, as they can reduce fuel consumption. Here the potential of magnesium based materials is addressed through double-tasking: a) establish innovative lean-manufacturing processes, avoid the classic melting step to substantially reduce carbon footprint of the magnesium products; b) encourage the using of no-melt processes, realizing high-resistant ultra-fined microstructures. The "Green Metallurgy 2020", a project funded by European Community in the LIFE+ 2009 Program, started in September 2010, coordinated by Politecnico di Milano (ITA) aims to scale to industrial route such impressive results experienced by CENIM (SPA) for some ultrafine bi-phase Mg -Zr (-Y) produced by no-melting route that achieved up to 400 MPa UTS and elongation capability of about 13%.

  14. Genetically engineered crops for biofuel production: regulatory perspectives.

    PubMed

    Lee, David; Chen, Alice; Nair, Ramesh

    2008-01-01

    There are numerous challenges in realizing the potential of biofuels that many policy makers have envisioned. The technical challenges in making the production of biofuels economical and on a scale to replace a significant fraction of transportation fuel have been well described, along with the potential environmental concerns. The use of biotechnology can potentially address many of these technical challenges and environmental concerns, but brings significant regulatory hurdles that have not been discussed extensively in the scientific community. This review will give an overview of the approaches being developed to produce transgenic biofuel feedstocks, particularly cellulosic ethanol, and the regulatory process in the United States that oversees the development and commercialization of new transgenic plants. We hope to illustrate that the level of regulation for transgenic organisms is not proportional to their potential risk to human health or the environment, and that revisions to the regulatory system in the U.S. currently under consideration are necessary to streamline the process.

  15. The interplay between group crossed products, semigroup crossed products and toeplitz algebras

    NASA Astrophysics Data System (ADS)

    Yusnitha, I.

    2018-05-01

    Realization of group crossed products constructed by decomposition, as semigroup crossed products. And connected it to Toeplitz algebra of ordered group quotient to get some preliminaries description for the further study on the structure of Toeplitz algebras of ordered group which is finitely generated.

  16. Suspension culture process for H9N2 avian influenza virus (strain Re-2).

    PubMed

    Wang, Honglin; Guo, Suying; Li, Zhenguang; Xu, Xiaoqin; Shao, Zexiang; Song, Guicai

    2017-10-01

    H9N2 avian influenza virus has caused huge economic loss for the Chinese poultry industry since it was first identified. Vaccination is frequently used as a control method for the disease. Meanwhile suspension culture has become an important tool for the development of influenza vaccines. To optimize the suspension culture conditions for the avian influenza H9N2 virus (Re-2 strain) in Madin-Darby Canine Kidney (MDCK) cells, we studied the culture conditions for cell growth and proliferation parameters for H9N2 virus replication. MDCK cells were successfully cultured in suspension, from a small scale to industrial levels of production, with passage time and initial cell density being optimized. The influence of pH on the culture process in the reactor has been discussed and the process parameters for industrial production were explored via amplification of the 650L reactor. Subsequently, we cultivated cells at high cell density and harvested high amounts of virus, reaching 10log2 (1:1024). Furthermore an animal experiment was conducted to detect antibody. Compared to the chicken embryo virus vaccine, virus cultured from MDCK suspension cells can produce a higher amount of antibodies. The suspension culture process is simple and cost efficient, thus providing a solid foundation for the realization of large-scale avian influenza vaccine production.

  17. Study of scratch drive actuator force characteristics

    NASA Astrophysics Data System (ADS)

    Li, Lijie; Brown, J. Gordon; Uttamchandani, Deepak

    2002-11-01

    Microactuators are one of the key components in MEMS technology, and various designs have been realized through different fabrication processes. One type of microactuator commonly used is the scratch drive actuator (SDA) that is frequently fabricated by surface micromachining processes. An experimental investigation has been conducted on the force characteristics of SDAs fabricated using the JDSU Microsystems MUMPs process. One-, two-, three- and four-plate SDAs connected to box-springs have been designed and fabricated for these experiments using MUMPs run 44. The spring constant for the box-springs has been calculated by FEM using ANSYS software. The product of the spring constant and spring extension is used to measure the forces produced by these SDAs. It is estimated that the forces produced exceed 250 μN from a one-plate SDA and 850 μN from a four-plate SDA.

  18. Quality cell therapy manufacturing by design.

    PubMed

    Lipsitz, Yonatan Y; Timmins, Nicholas E; Zandstra, Peter W

    2016-04-01

    Transplantation of live cells as therapeutic agents is poised to offer new treatment options for a wide range of acute and chronic diseases. However, the biological complexity of cells has hampered the translation of laboratory-scale experiments into industrial processes for reliable, cost-effective manufacturing of cell-based therapies. We argue here that a solution to this challenge is to design cell manufacturing processes according to quality-by-design (QbD) principles. QbD integrates scientific knowledge and risk analysis into manufacturing process development and is already being adopted by the biopharmaceutical industry. Many opportunities to incorporate QbD into cell therapy manufacturing exist, although further technology development is required for full implementation. Linking measurable molecular and cellular characteristics of a cell population to final product quality through QbD is a crucial step in realizing the potential for cell therapies to transform healthcare.

  19. Databases and coordinated research projects at the IAEA on atomic processes in plasmas

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Braams, Bastiaan J.; Chung, Hyun-Kyung

    2012-05-25

    The Atomic and Molecular Data Unit at the IAEA works with a network of national data centres to encourage and coordinate production and dissemination of fundamental data for atomic, molecular and plasma-material interaction (A+M/PMI) processes that are relevant to the realization of fusion energy. The Unit maintains numerical and bibliographical databases and has started a Wiki-style knowledge base. The Unit also contributes to A+M database interface standards and provides a search engine that offers a common interface to multiple numerical A+M/PMI databases. Coordinated Research Projects (CRPs) bring together fusion energy researchers and atomic, molecular and surface physicists for joint workmore » towards the development of new data and new methods. The databases and current CRPs on A+M/PMI processes are briefly described here.« less

  20. Optical implementation of inner product neural associative memory

    NASA Technical Reports Server (NTRS)

    Liu, Hua-Kuang (Inventor)

    1995-01-01

    An optical implementation of an inner-product neural associative memory is realized with a first spatial light modulator for entering an initial two-dimensional N-tuple vector and for entering a thresholded output vector image after each iteration until convergence is reached, and a second spatial light modulator for entering M weighted vectors of inner-product scalars multiplied with each of the M stored vectors, where the inner-product scalars are produced by multiplication of the initial input vector in the first iterative cycle (and thresholded vectors in subsequent iterative cycles) with each of the M stored vectors, and the weighted vectors are produced by multiplication of the scalars with corresponding ones of the stored vectors. A Hughes liquid crystal light valve is used for the dual function of summing the weighted vectors and thresholding the sum vector. The thresholded vector is then entered through the first spatial light modulator for reiteration of the process cycle until convergence is reached.

  1. A multi-sensor remote sensing approach for measuring primary production from space

    NASA Technical Reports Server (NTRS)

    Gautier, Catherine

    1989-01-01

    It is proposed to develop a multi-sensor remote sensing method for computing marine primary productivity from space, based on the capability to measure the primary ocean variables which regulate photosynthesis. The three variables and the sensors which measure them are: (1) downwelling photosynthetically available irradiance, measured by the VISSR sensor on the GOES satellite, (2) sea-surface temperature from AVHRR on NOAA series satellites, and (3) chlorophyll-like pigment concentration from the Nimbus-7/CZCS sensor. These and other measured variables would be combined within empirical or analytical models to compute primary productivity. With this proposed capability of mapping primary productivity on a regional scale, we could begin realizing a more precise and accurate global assessment of its magnitude and variability. Applications would include supplementation and expansion on the horizontal scale of ship-acquired biological data, which is more accurate and which supplies the vertical components of the field, monitoring oceanic response to increased atmospheric carbon dioxide levels, correlation with observed sedimentation patterns and processes, and fisheries management.

  2. Modeling design iteration in product design and development and its solution by a novel artificial bee colony algorithm.

    PubMed

    Chen, Tinggui; Xiao, Renbin

    2014-01-01

    Due to fierce market competition, how to improve product quality and reduce development cost determines the core competitiveness of enterprises. However, design iteration generally causes increases of product cost and delays of development time as well, so how to identify and model couplings among tasks in product design and development has become an important issue for enterprises to settle. In this paper, the shortcomings existing in WTM model are discussed and tearing approach as well as inner iteration method is used to complement the classic WTM model. In addition, the ABC algorithm is also introduced to find out the optimal decoupling schemes. In this paper, firstly, tearing approach and inner iteration method are analyzed for solving coupled sets. Secondly, a hybrid iteration model combining these two technologies is set up. Thirdly, a high-performance swarm intelligence algorithm, artificial bee colony, is adopted to realize problem-solving. Finally, an engineering design of a chemical processing system is given in order to verify its reasonability and effectiveness.

  3. Hydrolysis and regeneration of sodium borohydride (NaBH4) - A combination of hydrogen production and storage

    NASA Astrophysics Data System (ADS)

    Chen, W.; Ouyang, L. Z.; Liu, J. W.; Yao, X. D.; Wang, H.; Liu, Z. W.; Zhu, M.

    2017-08-01

    Sodium borohydride (NaBH4) hydrolysis is a promising approach for hydrogen generation, but it is limited by high costs, low efficiency of recycling the by-product, and a lack of effective gravimetric storage methods. Here we demonstrate the regeneration of NaBH4 by ball milling the by-product, NaBO2·2H2O or NaBO2·4H2O, with MgH2 at room temperature and atmospheric pressure without any further post-treatment. Record yields of NaBH4 at 90.0% for NaBO2·2H2O and 88.3% for NaBO2·4H2O are achieved. This process also produces hydrogen from the splitting of coordinate water in hydrated sodium metaborate. This compensates the need for extra hydrogen for generating MgH2. Accordingly, we conclude that our unique approach realizes an efficient and cost-effective closed loop system for hydrogen production and storage.

  4. The flexible feedstock concept in Industrial Biotechnology: Metabolic engineering of Escherichia coli, Corynebacterium glutamicum, Pseudomonas, Bacillus and yeast strains for access to alternative carbon sources.

    PubMed

    Wendisch, Volker F; Brito, Luciana Fernandes; Gil Lopez, Marina; Hennig, Guido; Pfeifenschneider, Johannes; Sgobba, Elvira; Veldmann, Kareen H

    2016-09-20

    Most biotechnological processes are based on glucose that is either present in molasses or generated from starch by enzymatic hydrolysis. At the very high, million-ton scale production volumes, for instance for fermentative production of the biofuel ethanol or of commodity chemicals such as organic acids and amino acids, competing uses of carbon sources e.g. in human and animal nutrition have to be taken into account. Thus, the biotechnological production hosts E. coli, C. glutamicum, pseudomonads, bacilli and Baker's yeast used in these large scale processes have been engineered for efficient utilization of alternative carbon sources. This flexible feedstock concept is central to the use of non-glucose second and third generation feedstocks in the emerging bioeconomy. The metabolic engineering efforts to broaden the substrate scope of E. coli, C. glutamicum, pseudomonads, B. subtilis and yeasts to include non-native carbon sources will be reviewed. Strategies to enable simultaneous consumption of mixtures of native and non-native carbon sources present in biomass hydrolysates will be summarized and a perspective on how to further increase feedstock flexibility for the realization of biorefinery processes will be given. Copyright © 2016 Elsevier B.V. All rights reserved.

  5. An amorphous silicon photodiode with 2 THz gain-bandwidth product based on cycling excitation process

    NASA Astrophysics Data System (ADS)

    Yan, Lujiang; Yu, Yugang; Zhang, Alex Ce; Hall, David; Niaz, Iftikhar Ahmad; Raihan Miah, Mohammad Abu; Liu, Yu-Hsin; Lo, Yu-Hwa

    2017-09-01

    Since impact ionization was observed in semiconductors over half a century ago, avalanche photodiodes (APDs) using impact ionization in a fashion of chain reaction have been the most sensitive semiconductor photodetectors. However, APDs have relatively high excess noise, a limited gain-bandwidth product, and high operation voltage, presenting a need for alternative signal amplification mechanisms of superior properties. As an amplification mechanism, the cycling excitation process (CEP) was recently reported in a silicon p-n junction with subtle control and balance of the impurity levels and profiles. Realizing that CEP effect depends on Auger excitation involving localized states, we made the counter intuitive hypothesis that disordered materials, such as amorphous silicon, with their abundant localized states, can produce strong CEP effects with high gain and speed at low noise, despite their extremely low mobility and large number of defects. Here, we demonstrate an amorphous silicon low noise photodiode with gain-bandwidth product of over 2 THz, based on a very simple structure. This work will impact a wide range of applications involving optical detection because amorphous silicon, as the primary gain medium, is a low-cost, easy-to-process material that can be formed on many kinds of rigid or flexible substrates.

  6. Numerical simulation study on rolling-chemical milling process of aluminum-lithium alloy skin panel

    NASA Astrophysics Data System (ADS)

    Huang, Z. B.; Sun, Z. G.; Sun, X. F.; Li, X. Q.

    2017-09-01

    Single curvature parts such as aircraft fuselage skin panels are usually manufactured by rolling-chemical milling process, which is usually faced with the problem of geometric accuracy caused by springback. In most cases, the methods of manual adjustment and multiple roll bending are used to control or eliminate the springback. However, these methods can cause the increase of product cost and cycle, and lead to material performance degradation. Therefore, it is of significance to precisely control the springback of rolling-chemical milling process. In this paper, using the method of experiment and numerical simulation on rolling-chemical milling process, the simulation model for rolling-chemical milling process of 2060-T8 aluminum-lithium alloy skin was established and testified by the comparison between numerical simulation and experiment results for the validity. Then, based on the numerical simulation model, the relative technological parameters which influence on the curvature of the skin panel were analyzed. Finally, the prediction of springback and the compensation can be realized by controlling the process parameters.

  7. Prospects of Supercritical Fluids in Realizing Graphene-Based Functional Materials.

    PubMed

    Padmajan Sasikala, Suchithra; Poulin, Philippe; Aymonier, Cyril

    2016-04-13

    Supercritical-fluids science and technology predate all the approaches that are currently established for graphene production by several decades in advanced materials design. However, it has only recently been proposed as a plausible approach for graphene processing. Since then, supercritical fluids have emerged into contention as an alternative to existing technologies because of their scalability and versatility in processing graphene materials, which include composites, aerogels, and foams. Here, an overview is presented of such materials prepared through supercritical fluids from an advanced materials science standpoint, with a discussion on their fundamental properties and technological applications. The benefits of supercritical-fluid processing over conventional liquid-phase processing are presented. The benefits include not only better performances for advanced applications but also environmental issues associated with the synthesis process. Nevertheless, the limitations of supercritical-fluid processing are also stressed, along with challenges that are still faced toward the achievement of the great expectations from graphene materials. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  8. FTIR characterization of Mexican honey and its adulteration with sugar syrups by using chemometric methods

    NASA Astrophysics Data System (ADS)

    Rios-Corripio, M. A.; Rios-Leal, E.; Rojas-López, M.; Delgado-Macuil, R.

    2011-01-01

    A chemometric analysis of adulteration of Mexican honey by sugar syrups such as corn syrup and cane sugar syrup was realized. Fourier transform infrared spectroscopy (FTIR) was used to measure the absorption of a group of bee honey samples from central region of Mexico. Principal component analysis (PCA) was used to process FTIR spectra to determine the adulteration of bee honey. In addition to that, the content of individual sugars from honey samples: glucose, fructose, sucrose and monosaccharides was determined by using PLS-FTIR analysis validated by HPLC measurements. This analytical methodology which is based in infrared spectroscopy and chemometry can be an alternative technique to characterize and also to determine the purity and authenticity of nutritional products as bee honey and other natural products.

  9. Microfluidic biolector-microfluidic bioprocess control in microtiter plates.

    PubMed

    Funke, Matthias; Buchenauer, Andreas; Schnakenberg, Uwe; Mokwa, Wilfried; Diederichs, Sylvia; Mertens, Alan; Müller, Carsten; Kensy, Frank; Büchs, Jochen

    2010-10-15

    In industrial-scale biotechnological processes, the active control of the pH-value combined with the controlled feeding of substrate solutions (fed-batch) is the standard strategy to cultivate both prokaryotic and eukaryotic cells. On the contrary, for small-scale cultivations, much simpler batch experiments with no process control are performed. This lack of process control often hinders researchers to scale-up and scale-down fermentation experiments, because the microbial metabolism and thereby the growth and production kinetics drastically changes depending on the cultivation strategy applied. While small-scale batches are typically performed highly parallel and in high throughput, large-scale cultivations demand sophisticated equipment for process control which is in most cases costly and difficult to handle. Currently, there is no technical system on the market that realizes simple process control in high throughput. The novel concept of a microfermentation system described in this work combines a fiber-optic online-monitoring device for microtiter plates (MTPs)--the BioLector technology--together with microfluidic control of cultivation processes in volumes below 1 mL. In the microfluidic chip, a micropump is integrated to realize distinct substrate flow rates during fed-batch cultivation in microscale. Hence, a cultivation system with several distinct advantages could be established: (1) high information output on a microscale; (2) many experiments can be performed in parallel and be automated using MTPs; (3) this system is user-friendly and can easily be transferred to a disposable single-use system. This article elucidates this new concept and illustrates applications in fermentations of Escherichia coli under pH-controlled and fed-batch conditions in shaken MTPs. Copyright 2010 Wiley Periodicals, Inc.

  10. Implications of recent new concepts on the future of mainstream laser processing

    NASA Astrophysics Data System (ADS)

    La Rocca, Aldo V.

    2000-07-01

    According to one of today's most accepted visualizations of the first viable realizations of The Computer Integrated Manufacturing Plant, C.I.M.P., the manufacturing systems herein discussed tend to be multiprocessing, and tend to incorporate the lasers to take advantage of the unique capacities of the laser as a processing tool. Finally also the present laser sources, while having been for a long time more than sufficient, inevitably tend also to new generations. Said visualizations stand in the belief that the first realizations of the C I M P most likely will use flexible multiprocessing machines, which, for flexibility requirements, grow in multi-station cells, in their aggregation in isles and finally in complete manufacturing centers. To constitute the CIMP all partaking elements must be the most easily amenable to Computer Aided Design, CAD, and Computer Aided Manufacturing, CAM. Another basic requirement is that all elements constituting the CIMP must possess the highest System Efficiency and Energy Efficiency at the level of the single element and of its aggregations throughout the various combinations at each and every operating level of said aggregations, up to that of the CIMP. The mastering of the CIMP design constitute a New Discipline that presents very formidable but necessary tasks. Of these the first examples were those related to the early flexible manufacturing system Design Programs. For what concerns the laser processing machines and their integration in manufacturing systems, attention must be given to not repeat the events that hindered their diffusion in the production field keeping it at a level much lower than the expectations and their true potential. Said events stemmed from the confusion between System Efficiency and Energy Efficiency, which persisted for too long and is still common. This has taken place at the levels of introduction of a single element into the combination of the several elements constituting a linear arrangement such as a Transfer Production Line. It because greater and with graver consequences in the case of arrangements possessing more than one degree of product routings, arrangements, as previously mentioned, which evolved in the Flexible Manufacturing Centers.

  11. Families of vector-like deformations of relativistic quantum phase spaces, twists and symmetries

    NASA Astrophysics Data System (ADS)

    Meljanac, Daniel; Meljanac, Stjepan; Pikutić, Danijel

    2017-12-01

    Families of vector-like deformed relativistic quantum phase spaces and corresponding realizations are analyzed. A method for a general construction of the star product is presented. The corresponding twist, expressed in terms of phase space coordinates, in the Hopf algebroid sense is presented. General linear realizations are considered and corresponding twists, in terms of momenta and Poincaré-Weyl generators or gl(n) generators are constructed and R-matrix is discussed. A classification of linear realizations leading to vector-like deformed phase spaces is given. There are three types of spaces: (i) commutative spaces, (ii) κ -Minkowski spaces and (iii) κ -Snyder spaces. The corresponding star products are (i) associative and commutative (but non-local), (ii) associative and non-commutative and (iii) non-associative and non-commutative, respectively. Twisted symmetry algebras are considered. Transposed twists and left-right dual algebras are presented. Finally, some physical applications are discussed.

  12. Patterning of OPV modules by ultra-fast laser

    NASA Astrophysics Data System (ADS)

    Kubiš, Peter; Lucera, Luca; Guo, Fei; Spyropolous, George; Voigt, Monika M.; Brabec, Christoph J.

    2014-10-01

    A novel production process combining slot-die coating, transparent flexible IMI (ITO-Metal-ITO) electrodes and ultra-fast laser ablation can be used for the realization of P3HT:PCBM based thin film flexible OPV modules. The fast and precise laser ablation allows an overall efficiency over 3 % and a device geometric fill factor (GFF) over 95 %. Three functional layers can be ablated using the same wavelength only with varying the laser fluence and overlap. Different OPV device architectures with multilayers utilizing various materials are challenging for ablation but can be structured by using a systematical approach.

  13. [Mobile autonomous robots-Possibilities and limits].

    PubMed

    Maehle, E; Brockmann, W; Walthelm, A

    2002-02-01

    Besides industrial robots, which today are firmly established in production processes, service robots are becoming more and more important. They shall provide services for humans in different areas of their professional and everyday environment including medicine. Most of these service robots are mobile which requires an intelligent autonomous behaviour. After characterising the different kinds of robots the relevant paradigms of intelligent autonomous behaviour for mobile robots are critically discussed in this paper and illustrated by three concrete examples of robots realized in Lübeck. In addition a short survey of actual kinds of surgical robots as well as an outlook to future developments is given.

  14. The Kinetic Nonequilibrium Processes in the Internal Flow and in the Plume of Subsonic and Supersonic Aircrafts

    NASA Technical Reports Server (NTRS)

    Starik, Alexander M.

    1997-01-01

    (1) Our results show that under combustion of thermal destruction products of n-C8H18, and other hydrocarbon fuels with air at the equivalent ratio -0.5 and less the chemical equilibrium is not realized at the exit plane of combustion chamber and in the gas turbine and nozzle for most of small components such as NO2, NO3, HNO, HNO2, HNO3, N(x)H(y), HO2, OH. The chemical equilibrium is not realized in the internal flow of ramjet hydrogen combustion engine too. So at the nozzle exit plane both of gas-turbine hydrocarbon combustion engine and of ramjet hydrogen combustion engine the relatively large values of concentration of such small components as NO3, HNO2, N2O, HNO3, HNO, NH, N2H, HO2, H2O2 may be realized. The exact definition of these component concentration as well as concentration of NO(x), OH, SO2, O, H, H2, H2O at the nozzle exit plane is very important for plume chemistry. (2) The results which were obtained for subsonic and hypersonic aircrafts indicate on the considerable change of the composition of the gas mixture along the plume. This change can be caused not only by the mixture of combustion products with the atmosphere air but by proceeding of whole complex of nonequilibrium photochemical reactions. The photodissociation processes begin to influence on the formation of the free atoms and radicals at flight altitude H greater than or equal to 18 km. Neglect of these processes can result in essential (up to 10(exp 4) times) mistakes of values gamma(sub OH), gamma(sub O), gamma(sub H), gamma(sub HSO3) and some products of CFC's disintegration. It was found that penetration of Cl-containing species from the atmosphere into the exhaust flow and its interaction with nitrogen oxides leads to essential increasing of the concentration of Cl, Cl2, ClO2, ClNO3, CH3Cl and sometimes HCl and the decreasing of ClO concentration by comparison with background values. The results of our analysis show that the plume aircraft with both hydrocarbon and hydrogen combustion engine may be source of various pollutant components such as HNO, HNO4,ClO2, CH3NO2, CH3NO3, CH2O, Cl, H2O2, but not only NO, NO2, HNO2, HNO3, N2O5, SO2, SO3, H2SO4 as it was supposed before.

  15. The importance of forest structure to biodiversity–productivity relationships

    PubMed Central

    Huth, Andreas

    2017-01-01

    While various relationships between productivity and biodiversity are found in forests, the processes underlying these relationships remain unclear and theory struggles to coherently explain them. In this work, we analyse diversity–productivity relationships through an examination of forest structure (described by basal area and tree height heterogeneity). We use a new modelling approach, called ‘forest factory’, which generates various forest stands and calculates their annual productivity (above-ground wood increment). Analysing approximately 300 000 forest stands, we find that mean forest productivity does not increase with species diversity. Instead forest structure emerges as the key variable. Similar patterns can be observed by analysing 5054 forest plots of the German National Forest Inventory. Furthermore, we group the forest stands into nine forest structure classes, in which we find increasing, decreasing, invariant and even bell-shaped relationships between productivity and diversity. In addition, we introduce a new index, called optimal species distribution, which describes the ratio of realized to the maximal possible productivity (by shuffling species identities). The optimal species distribution and forest structure indices explain the obtained productivity values quite well (R2 between 0.7 and 0.95), whereby the influence of these attributes varies within the nine forest structure classes. PMID:28280550

  16. Human communication needs and organizational productivity: the potential impact of office automation.

    PubMed

    Culnan, M J; Bair, J H

    1983-05-01

    Much of what white collar workers do in offices is communication-related. White collar workers make up the majority of the labor force in the United States today and the majority of current labor costs. Because office automation represents more productive structured techniques for handling both written and oral communication, office automation therefore offers the potential to make organizations more productive by improving organizational communication. This article: (1) defines communication, (2) identifies the potential benefits to be realized from implementing office automation, and (3) offers caveats related to the implementation of office automation systems. Realization of the benefits of office automation depends upon the degree to which new modes of communication may be successfully substituted for traditional modes.

  17. Experiences in flip chip production of radiation detectors

    NASA Astrophysics Data System (ADS)

    Savolainen-Pulli, Satu; Salonen, Jaakko; Salmi, Jorma; Vähänen, Sami

    2006-09-01

    Modern imaging devices often require heterogeneous integration of different materials and technologies. Because of yield considerations, material availability, and various technological limitations, an extremely fine pitch is necessary to realize high-resolution images. Thus, there is a need for a hybridization technology that is able to join together readout amplifiers and pixel detectors at a very fine pitch. This paper describes radiation detector flip chip production at VTT. Our flip chip technology utilizes 25-μm diameter tin-lead solder bumps at a 50-μm pitch and is based on flux-free bonding. When preprocessed wafers are used, as is the case here, the total yield is defined only partly by the flip chip process. Wafer preprocessing done by a third-party silicon foundry and the flip chip process create different process defects. Wafer-level yield maps (based on probing) provided by the customer are used to select good readout chips for assembly. Wafer probing is often done outside of a real clean room environment, resulting in particle contamination and/or scratches on the wafers. Factors affecting the total yield of flip chip bonded detectors are discussed, and some yield numbers of the process are given. Ways to improve yield are considered, and finally guidelines for process planning and device design with respect to yield optimization are given.

  18. Surface modification and its role in the preparation of FeSi gradient alloys with good magnetic property and ductility

    NASA Astrophysics Data System (ADS)

    Yu, Haiyuan; Bi, Xiaofang

    2018-04-01

    Realization of the effective Si penetration at a lower processing temperature is a challenge, but of significance in reducing the strict requirements for the equipment and realizing cost-cutting in production. In this work, we have modified the surface microstructure of Fe-3 wt%Si alloy by using surface mechanical attrition treatment. The modified surface microstructure is characteristic of nanocrystalline, which is found to significantly enhance the efficiency of subsequent Si penetration into the alloy, and successively leading to the decrease of penetration temperature up to 200 °C. As a consequence, the Si gradient distribution across thickness can be readily controlled by changing penetration time, and FeSi alloys with various gradients are prepared by chemical vapor deposition along with subsequent annealing process. The dependence of magnetic and mechanical properties on Si gradient for demonstrates that the increase of Si gradient reduces core losses, especially at higher frequencies, and meanwhile improves ductility of FeSi alloys as well. The mechanism underlying the effect of Si gradient is clarified by combining magnetostriction measurement and domain structure observations. This work provides a facile and effective way for achieving gradient FeSi alloys with good magnetic property and ductility.

  19. The influence of computer-generated path on the robot’s effector stability of motion

    NASA Astrophysics Data System (ADS)

    Foit, K.; Banaś, W.; Gwiazda, A.; Ćwikła, G.

    2017-08-01

    The off-line trajectory planning is often carried out due to economical and practical reasons: the robot is not excluded from the production process and the operator could benefit from testing programs in the virtual environment. On the other hand, the dedicated off-line programming and simulation software is often limited in features and is intended to roughly check the program. It should be expected that the arm of the real robot’s manipulator will realize the trajectory in different manner: the acceleration and deceleration phases may trigger the vibrations of the kinematic chain that could affect the precision of effector positioning and degrade the quality of process realized by the robot. The purpose of this work is the analysis of the selected cases, when the robot’s effector has been moved along the programmed path. The off-line generated, test trajectories have different arrangement of points: such approach has allowed evaluating the time needed to complete the each of the tasks, as well as measuring the level of the vibration of the robot’s wrist. All tests were performed without the load. The conclusions of the experiment may be useful during the trajectory planning in order to avoid the critical configuration of points.

  20. A laser induced local transfer for patterning of RGB-OLED-displays

    NASA Astrophysics Data System (ADS)

    Kroeger, Michael; Hueske, Marc; Dobbertin, Thomas; Meyer, Jens; Krautwald, Henning; Riedl, Thomas; Johannes, Hans-Hermann; Kowalsky, Wolfgang

    2005-07-01

    RGB-OLED-displays can be realized by at least three different approaches: Color from white, color from blue or patterning of red, green and blue OLEDs, which is favorable for reasons of higher efficiency and lower costs. Common patterning techniques like photolithography cannot be applied due to the degradation of the OLEDs after the exposure to solvents. Shadow masking which is currently widely applied is not applicable for bigger substrate sizes of future mass production tools. Therefore a novel approach for patterning of organic semiconductors will be demonstrated. The laser induced local transfer (LILT) of organic small molecule materials allows for mass production of high resolution RGB-OLED-displays. An infrared absorbing target is coated with the desired emitting material, which is placed in a short distance in front of an OLED substrate. A scanner deflects and focuses an infrared laser beam onto the target. By adjusting scanning speed and laser power accurately the target locally heats up to a temperature where the organic material sublimes and will be deposited on the opposite OLED substrate. By repeating this for red, green and blue emitting materials a RGB-OLED-display can be realized. For process evaluation and development a LILT-module has been built, incorporating two custom vacuum chambers, several lift and transfer stages, a high-speed high-precision scanner and an infrared continuous-wave laser (cw). This module is designed to be part of a future inline deposition system for full-color OLED displays. In the first experiments it could be observed, that the pattern resolution is strongly dependent on the scanning speed, exhibiting minimum feature sizes of 40μm. It can be deducted that this is due to the laser's beam profile (TEM00), which allows for the smallest focus possible, but may not allow for rugged process conditions suitable for production. Rectangular steep-edged beam profiles may overcome this problem.

  1. Technology, energy and the environment

    NASA Astrophysics Data System (ADS)

    Mitchell, Glenn Terry

    This dissertation consists of three distinct papers concerned with technology, energy and the environment. The first paper is an empirical analysis of production under uncertainty, using agricultural production data from the central United States. Unlike previous work, this analysis identifies the effect of actual realizations of weather as well as farmers' expectations about weather. The results indicate that both of these are significant factors explaining short run profits in agriculture. Expectations about weather, called climate, affect production choices, and actual weather affects realized output. These results provide better understanding of the effect of climate change in agriculture. The second paper examines how emissions taxes induce innovation that reduces pollution. A polluting firm chooses technical improvement to minimize cost over an infinite horizon, given an emission tax set by a planner. This leads to a solution path for technical change. Changes in the tax rate affect the path for innovation. Setting the tax at equal to the marginal damage (which is optimal in a static setting with no technical change) is not optimal in the presence of technical change. When abatement is also available as an alternative to technical change, changes in the tax can have mixed effects, due to substitution effects. The third paper extends the theoretical framework for exploring the diffusion of new technologies. Information about new technologies spreads through the economy by means of a network. The pattern of diffusion will depend on the structure of this network. Observed networks are the result of an evolutionary process. This paper identifies how these evolutionary outcomes compare with optimal solutions. The conditions guaranteeing convergence to an optimal outcome are quite stringent. It is useful to determine the set of initial population states that do converge to an optimal outcome. The distribution of costs and benefits among the agents within an information processing structure plays a critical role in defining this set. These distributional arrangements represent alternative institutional regimes. Institutional changes can improve outcomes, free the flow of information, and encourage the diffusion of profitable new technologies.

  2. Private and Public Manpower Policies to Stimulate Productivity.

    ERIC Educational Resources Information Center

    Ginzberg, Eli; And Others

    Realizing the relationship of productivity to technological, organizational, and manpower variables, and the need to improve and increase production gains, this document examines existing public and private entrepreneurial and industrial relations structures in an effort to ascertain manpower policy measures which if strengthened or introduced…

  3. Individual Learning Route as a Way of Highly Qualified Specialists Training for Extraction of Solid Commercial Minerals Enterprises

    NASA Astrophysics Data System (ADS)

    Oschepkova, Elena; Vasinskaya, Irina; Sockoluck, Irina

    2017-11-01

    In view of changing educational paradigm (adopting of two-tier system of higher education concept - undergraduate and graduate programs) a need of using of modern learning and information and communications technologies arises putting into practice learner-centered approaches in training of highly qualified specialists for extraction and processing of solid commercial minerals enterprises. In the unstable market demand situation and changeable institutional environment, from one side, and necessity of work balancing, supplying conditions and product quality when mining-and-geological parameters change, from the other side, mining enterprises have to introduce and develop the integrated management process of product and informative and logistic flows under united management system. One of the main limitations, which keeps down the developing process on Russian mining enterprises, is staff incompetence at all levels of logistic management. Under present-day conditions extraction and processing of solid commercial minerals enterprises need highly qualified specialists who can do self-directed researches, develop new and improve present arranging, planning and managing technologies of technical operation and commercial exploitation of transport and transportation and processing facilities based on logistics. Learner-centered approach and individualization of the learning process necessitate the designing of individual learning route (ILR), which can help the students to realize their professional facilities according to requirements for specialists for extraction and processing of solid commercial minerals enterprises.

  4. Using PAT to accelerate the transition to continuous API manufacturing.

    PubMed

    Gouveia, Francisca F; Rahbek, Jesper P; Mortensen, Asmus R; Pedersen, Mette T; Felizardo, Pedro M; Bro, Rasmus; Mealy, Michael J

    2017-01-01

    Significant improvements can be realized by converting conventional batch processes into continuous ones. The main drivers include reduction of cost and waste, increased safety, and simpler scale-up and tech transfer activities. Re-designing the process layout offers the opportunity to incorporate a set of process analytical technologies (PAT) embraced in the Quality-by-Design (QbD) framework. These tools are used for process state estimation, providing enhanced understanding of the underlying variability in the process impacting quality and yield. This work describes a road map for identifying the best technology to speed-up the development of continuous processes while providing the basis for developing analytical methods for monitoring and controlling the continuous full-scale reaction. The suitability of in-line Raman, FT-infrared (FT-IR), and near-infrared (NIR) spectroscopy for real-time process monitoring was investigated in the production of 1-bromo-2-iodobenzene. The synthesis consists of three consecutive reaction steps including the formation of an unstable diazonium salt intermediate, which is critical to secure high yield and avoid formation of by-products. All spectroscopic methods were able to capture critical information related to the accumulation of the intermediate with very similar accuracy. NIR spectroscopy proved to be satisfactory in terms of performance, ease of installation, full-scale transferability, and stability to very adverse process conditions. As such, in-line NIR was selected to monitor the continuous full-scale production. The quantitative method was developed against theoretical concentration values of the intermediate since representative sampling for off-line reference analysis cannot be achieved. The rapid and reliable analytical system allowed the following: speeding up the design of the continuous process and a better understanding of the manufacturing requirements to ensure optimal yield and avoid unreacted raw materials and by-products in the continuous reactor effluent. Graphical Abstract Using PAT to accelerate the transition to continuous API manufacturing.

  5. Enhancement of high-solids enzymatic hydrolysis of corncob residues by bisulfite pretreatment for biorefinery.

    PubMed

    Xing, Yang; Bu, Lingxi; Zheng, Tianran; Liu, Shijie; Jiang, Jianxin

    2016-12-01

    Co-production of glucose, furfural and other green materials based on a lignocellulosic biorefinery is a promising way to realize the commercial application of corncob residues. An effective process was developed for glucose production using low temperature bisulfite pretreatment and high-solids enzymatic hydrolysis. Corncob residues from furfural production (FRs) were pretreated with 0.1g NaHSO 3 /g dry substrate at 100°C for 3h. Lignin was sulfonated and sulfonic groups were produced during pretreatment, which resulted in decreasing the zeta potential of the samples. Compared with raw material, bisulfite pretreatment of FRs increased the glucose yield from 18.6 to 99.45% after 72h hydrolysis at a solids loading of 12.5%. The hydrolysis residues showed a relatively high thermal stability and concentrated high derivatives. Direct pretreatment followed by enzymatic hydrolysis is an environmentally-friendly and economically-feasible method for the production of glucose and high-purity lignin, which could be further converted into high-value products. Copyright © 2016 Elsevier Ltd. All rights reserved.

  6. A Study on Real-Time Scheduling Methods in Holonic Manufacturing Systems

    NASA Astrophysics Data System (ADS)

    Iwamura, Koji; Taimizu, Yoshitaka; Sugimura, Nobuhiro

    Recently, new architectures of manufacturing systems have been proposed to realize flexible control structures of the manufacturing systems, which can cope with the dynamic changes in the volume and the variety of the products and also the unforeseen disruptions, such as failures of manufacturing resources and interruptions by high priority jobs. They are so called as the autonomous distributed manufacturing system, the biological manufacturing system and the holonic manufacturing system. Rule-based scheduling methods were proposed and applied to the real-time production scheduling problems of the HMS (Holonic Manufacturing System) in the previous report. However, there are still remaining problems from the viewpoint of the optimization of the whole production schedules. New procedures are proposed, in the present paper, to select the production schedules, aimed at generating effective production schedules in real-time. The proposed methods enable the individual holons to select suitable machining operations to be carried out in the next time period. Coordination process among the holons is also proposed to carry out the coordination based on the effectiveness values of the individual holons.

  7. Allergen source materials: state-of-the-art.

    PubMed

    Esch, Robert E

    2009-01-01

    A variety of positive outcomes can be realized from validation and risk management activities (see Table 4). They are dependent on the participation of multiple functional groups including the quality unit, regulatory and legal affairs, engineering and production operations, research and development, and sales and marketing. Quality risk management is receiving increased attention in the area of public health, pharmacovigilance, and pharmaceutical manufacturing. Recent examples of its regulatory use in our industry include the assessment of the potential risks of transmissible spongiform encephalopathies (TSE) agents through contaminated products], the risks of precipitates in allergenic extracts, and the revision of the potency limits for standardized dust mite and grass allergen vaccines. Its application to allergen source material process validation activities allowed for a practical strategy, especially in a complex manufacturing environment involving hundreds of products with multiple intended uses. In addition, the use of tools such as FMEA was useful in evaluating proposed changes made to manufacturing procedures and product specifications, new regulatory actions, and customer feedback or complaints. The success of such a quality assurance programs will ultimately be reflected in the elimination or reduction of product failures, improvement in the detection and prediction of potential product failures, and increased confidence in product quality.

  8. Online detecting system of roller wear based on laser-linear array CCD technology

    NASA Astrophysics Data System (ADS)

    Guo, Yuan

    2010-10-01

    Roller is an important metallurgy tool in the rolling mill. And the surface of a roller affects the quantity of the rolling product directly. After using a period of time, roller must be repaired or replaced. Examining the profile of a working roller between the intervals of rolling is called online detecting for roller wear. The study of online detecting roller wear is very important for selecting the grinding time in reason, reducing the exchanging times of rollers, improving the quality of the product and realizing online grinding rollers. By applying the laser-linear array CCD detective technology, a method for online non-touch detecting roller wear was brought forward. The principle, composition and the operation process of the linear array CCD detecting system were expatiated. And an error compensation algorithm is exactly calculated to offset the shift of the roller axis in this measurement system. So the stability and the accuracy were improved remarkably. The experiment proves that the accuracy of the detecting system reaches to the demand of practical production process. It can provide a new method of high speed and high accuracy online detecting for roller wear.

  9. Thermoplastic nanofluidic devices for biomedical applications.

    PubMed

    Weerakoon-Ratnayake, Kumuditha M; O'Neil, Colleen E; Uba, Franklin I; Soper, Steven A

    2017-01-31

    Microfluidics is now moving into a developmental stage where basic discoveries are being transitioned into the commercial sector so that these discoveries can affect, for example, healthcare. Thus, high production rate microfabrication technologies, such as thermal embossing and/or injection molding, are being used to produce low-cost consumables appropriate for commercial applications. Based on recent reports, it is clear that nanofluidics offers some attractive process capabilities that may provide unique venues for biomolecular analyses that cannot be realized at the microscale. Thus, it would be attractive to consider early in the developmental cycle of nanofluidics production pipelines that can generate devices possessing sub-150 nm dimensions in a high production mode and at low-cost to accommodate the commercialization of this exciting technology. Recently, functional sub-150 nm thermoplastic nanofluidic devices have been reported that can provide high process yield rates, which can enable commercial translation of nanofluidics. This review presents an overview of recent advancements in the fabrication, assembly, surface modification and the characterization of thermoplastic nanofluidic devices. Also, several examples in which nanoscale phenomena have been exploited for the analysis of biomolecules are highlighted. Lastly, some general conclusions and future outlooks are presented.

  10. User input in iterative design for prevention product development: leveraging interdisciplinary methods to optimize effectiveness.

    PubMed

    Guthrie, Kate M; Rosen, Rochelle K; Vargas, Sara E; Guillen, Melissa; Steger, Arielle L; Getz, Melissa L; Smith, Kelley A; Ramirez, Jaime J; Kojic, Erna M

    2017-10-01

    The development of HIV-preventive topical vaginal microbicides has been challenged by a lack of sufficient adherence in later stage clinical trials to confidently evaluate effectiveness. This dilemma has highlighted the need to integrate translational research earlier in the drug development process, essentially applying behavioral science to facilitate the advances of basic science with respect to the uptake and use of biomedical prevention technologies. In the last several years, there has been an increasing recognition that the user experience, specifically the sensory experience, as well as the role of meaning-making elicited by those sensations, may play a more substantive role than previously thought. Importantly, the role of the user-their sensory perceptions, their judgements of those experiences, and their willingness to use a product-is critical in product uptake and consistent use post-marketing, ultimately realizing gains in global public health. Specifically, a successful prevention product requires an efficacious drug, an efficient drug delivery system, and an effective user. We present an integrated iterative drug development and user experience evaluation method to illustrate how user-centered formulation design can be iterated from the early stages of preclinical development to leverage the user experience. Integrating the user and their product experiences into the formulation design process may help optimize both the efficiency of drug delivery and the effectiveness of the user.

  11. Kinetic modeling of light limitation and sulfur deprivation effects in the induction of hydrogen production with Chlamydomonas reinhardtii: Part I. Model development and parameter identification.

    PubMed

    Fouchard, Swanny; Pruvost, Jérémy; Degrenne, Benoit; Titica, Mariana; Legrand, Jack

    2009-01-01

    Chlamydomonas reinhardtii is a green microalga capable of turning its metabolism towards H2 production under specific conditions. However this H2 production, narrowly linked to the photosynthetic process, results from complex metabolic reactions highly dependent on the environmental conditions of the cells. A kinetic model has been developed to relate culture evolution from standard photosynthetic growth to H2 producing cells. It represents transition in sulfur-deprived conditions, known to lead to H2 production in Chlamydomonas reinhardtii, and the two main processes then induced which are an over-accumulation of intracellular starch and a progressive reduction of PSII activity for anoxia achievement. Because these phenomena are directly linked to the photosynthetic growth, two kinetic models were associated, the first (one) introducing light dependency (Haldane type model associated to a radiative light transfer model), the second (one) making growth a function of available sulfur amount under extracellular and intracellular forms (Droop formulation). The model parameters identification was realized from experimental data obtained with especially designed experiments and a sensitivity analysis of the model to its parameters was also conducted. Model behavior was finally studied showing interdependency between light transfer conditions, photosynthetic growth, sulfate uptake, photosynthetic activity and O2 release, during transition from oxygenic growth to anoxic H2 production conditions.

  12. Galileo - The Serial-Production AIT Challenge

    NASA Technical Reports Server (NTRS)

    Ragnit, Ulrike; Brunner, Otto

    2008-01-01

    The Galileo Project is one of the most demanding projects of ESA, being Europe's autarkic navigation system and a constellation composed of 30 satellites. This presentation points out the different phases of the project up to the full operational capability and the corresponding launch options with respect to launch vehicles as well as launch configurations. One of the biggest challenges is to set up a small serial 'production line' for the overall integration and test campaign of satellites. This production line demands an optimization of all relevant tasks, taking into account also backup and recovery actions. A comprehensive AIT concept is required, reflecting a tightly merged facility layout and work flow design. In addition a common data management system is needed to handle all spacecraft related documentation and to have a direct input-out flow for all activities, phases and positions at the same time. Process optimization is a well known field of engineering in all small high tech production lines, nevertheless serial production of satellites are still not the daily task in space business and therefore new concepts have to be put in place. Therefore, and in order to meet the satellites overall system optimization, a thorough interface between unit/subsystem manufacturing and satellite AIT must be realized to ensure a smooth flow and to avoid any process interruption, which would directly lead to a schedule impact.

  13. Fully Depleted Ti-Nb-Ta-Zr-O Nanotubes: Interfacial Charge Dynamics and Solar Hydrogen Production.

    PubMed

    Chiu, Yi-Hsuan; Lai, Ting-Hsuan; Chen, Chun-Yi; Hsieh, Ping-Yen; Ozasa, Kazunari; Niinomi, Mitsuo; Okada, Kiyoshi; Chang, Tso-Fu Mark; Matsushita, Nobuhiro; Sone, Masato; Hsu, Yung-Jung

    2018-05-01

    Poor kinetics of hole transportation at the electrode/electrolyte interface is regarded as a primary cause for the mediocre performance of n-type TiO 2 photoelectrodes. By adopting nanotubes as the electrode backbone, light absorption and carrier collection can be spatially decoupled, allowing n-type TiO 2 , with its short hole diffusion length, to maximize the use of the available photoexcited charge carriers during operation in photoelectrochemical (PEC) water splitting. Here, we presented a delicate electrochemical anodization process for the preparation of quaternary Ti-Nb-Ta-Zr-O mixed-oxide (denoted as TNTZO) nanotube arrays and demonstrated their utility in PEC water splitting. The charge-transfer dynamics for the electrodes was investigated using time-resolved photoluminescence, electrochemical impedance spectroscopy, and the decay of open-circuit voltage analysis. Data reveal that the superior photoactivity of TNTZO over pristine TiO 2 originated from the introduction of Nd, Ta, and Zr elements, which enhanced the amount of accessible charge carriers, modified the electronic structure, and improved the hole injection kinetics for expediting water splitting. By modulating the water content of the electrolyte employed in the anodization process, the wall thickness of the grown TNTZO nanotubes can be reduced to a size smaller than that of the depletion layer thickness, realizing a fully depleted state for charge carriers to further advance the PEC performance. Hydrogen evolution tests demonstrate the practical efficacy of TNTZO for realizing solar hydrogen production. Furthermore, with the composition complexity and fully depleted band structure, the present TNTZO nanotube arrays may offer a feasible and universal platform for the loading of other semiconductors to construct a sophisticated heterostructure photoelectrode paradigm, in which the photoexcited charge carriers can be entirely utilized for efficient solar-to-fuel conversion.

  14. New method of 2-dimensional metrology using mask contouring

    NASA Astrophysics Data System (ADS)

    Matsuoka, Ryoichi; Yamagata, Yoshikazu; Sugiyama, Akiyuki; Toyoda, Yasutaka

    2008-10-01

    We have developed a new method of accurately profiling and measuring of a mask shape by utilizing a Mask CD-SEM. The method is intended to realize high accuracy, stability and reproducibility of the Mask CD-SEM adopting an edge detection algorithm as the key technology used in CD-SEM for high accuracy CD measurement. In comparison with a conventional image processing method for contour profiling, this edge detection method is possible to create the profiles with much higher accuracy which is comparable with CD-SEM for semiconductor device CD measurement. This method realizes two-dimensional metrology for refined pattern that had been difficult to measure conventionally by utilizing high precision contour profile. In this report, we will introduce the algorithm in general, the experimental results and the application in practice. As shrinkage of design rule for semiconductor device has further advanced, an aggressive OPC (Optical Proximity Correction) is indispensable in RET (Resolution Enhancement Technology). From the view point of DFM (Design for Manufacturability), a dramatic increase of data processing cost for advanced MDP (Mask Data Preparation) for instance and surge of mask making cost have become a big concern to the device manufacturers. This is to say, demands for quality is becoming strenuous because of enormous quantity of data growth with increasing of refined pattern on photo mask manufacture. In the result, massive amount of simulated error occurs on mask inspection that causes lengthening of mask production and inspection period, cost increasing, and long delivery time. In a sense, it is a trade-off between the high accuracy RET and the mask production cost, while it gives a significant impact on the semiconductor market centered around the mask business. To cope with the problem, we propose the best method of a DFM solution using two-dimensional metrology for refined pattern.

  15. 16 CFR 1031.9 - Purpose and scope.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION GENERAL COMMISSION PARTICIPATION AND COMMISSION...) This subpart sets forth the Consumer Product Safety Commission's criteria and requirements governing... development bodies. (b) The Commission realizes there are advantages and benefits afforded by greater...

  16. Systems-Level Synthetic Biology for Advanced Biofuel Production

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ruffing, Anne; Jensen, Travis J.; Strickland, Lucas Marshall

    2015-03-01

    Cyanobacteria have been shown to be capable of producing a variety of advanced biofuels; however, product yields remain well below those necessary for large scale production. New genetic tools and high throughput metabolic engineering techniques are needed to optimize cyanobacterial metabolisms for enhanced biofuel production. Towards this goal, this project advances the development of a multiple promoter replacement technique for systems-level optimization of gene expression in a model cyanobacterial host: Synechococcus sp. PCC 7002. To realize this multiple-target approach, key capabilities were developed, including a high throughput detection method for advanced biofuels, enhanced transformation efficiency, and genetic tools for Synechococcusmore » sp. PCC 7002. Moreover, several additional obstacles were identified for realization of this multiple promoter replacement technique. The techniques and tools developed in this project will help to enable future efforts in the advancement of cyanobacterial biofuels.« less

  17. Hydraulophones: Acoustic musical instruments and expressive user interfaces

    NASA Astrophysics Data System (ADS)

    Janzen, Ryan E.

    Fluid flow creates an expansive range of acoustic possibilities, particularly in the case of water, which has unique turbulence and vortex shedding properties as compared with the air of ordinary wind instruments. Sound from water flow is explained with reference to a new class of musical instruments, hydraulophones, in which oscillation originates directly from matter in its liquid state. Several hydraulophones which were realized in practical form are described. A unique user-interface consisting of a row of water jets is presented, in terms of its expressiveness, tactility, responsiveness to derivatives and integrals of displacement, and in terms of the direct physical interaction between a user and the physical process of sound production. Signal processing algorithms are introduced, which extract further information from turbulent water flow, for industrial applications as well as musical applications.

  18. Nanoparticles in Polymers: Assembly, Rheology and Properties

    NASA Astrophysics Data System (ADS)

    Rao, Yuanqiao

    Inorganic nanoparticles have the potential of providing functionalities that are difficult to realize using organic materials; and nanocomposites is an effective mean to impart processibility and construct bulk materials with breakthrough properties. The dispersion and assembly of nanoparticles are critical to both processibility and properties of the resulting product. In this talk, we will discuss several methods to control the hierarchical structure of nanoparticles in polymers and resulting rheological, mechanical and optical properties. In one example, polymer-particle interaction and secondary microstructure were designed to provide a low viscosity composition comprising exfoliated high aspect ratio clay nanoparticles; in another example, the microstructure control through templates was shown to enable unique thermal mechanical and optical properties. Jeff Munro, Stephanie Potisek, Phillip Hustad; all of the Dow Chemical Company are co-authors.

  19. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mou, J.I.; King, C.

    The focus of this study is to develop a sensor fused process modeling and control methodology to model, assess, and then enhance the performance of a hexapod machine for precision product realization. Deterministic modeling technique was used to derive models for machine performance assessment and enhancement. Sensor fusion methodology was adopted to identify the parameters of the derived models. Empirical models and computational algorithms were also derived and implemented to model, assess, and then enhance the machine performance. The developed sensor fusion algorithms can be implemented on a PC-based open architecture controller to receive information from various sensors, assess themore » status of the process, determine the proper action, and deliver the command to actuators for task execution. This will enhance a hexapod machine`s capability to produce workpieces within the imposed dimensional tolerances.« less

  20. Low-cost solar array project progress and plans

    NASA Technical Reports Server (NTRS)

    Callaghan, W. T.

    1981-01-01

    The considered project is part of the DOE Photovoltaic Technology and Market Development Program. This program is concerned with the development and the utilization of cost-competitive photovoltaic systems. The project has the objective to develop, by 1986, the national capability to manufacture low-cost, long-life photovoltaic arrays at production rates that will realize economies of scale, and at a price of less than $0.70/watt. The array performance objectives include an efficiency greater than 10% and an operating lifetime longer than 20 years. The objective of the silicon material task is to establish the practicality of processes for producing silicon suitable for terrestrial photovoltaic applications at a price of $14/kg. The large-area sheet task is concerned with the development of process technology for sheet formation. Low-cost encapsulation material systems are being developed in connection with the encapsulation task. Another project goal is related to the development of economical process sequences.

  1. Launch processing system transition from development to operation

    NASA Technical Reports Server (NTRS)

    Paul, H. C.

    1977-01-01

    The Launch Processing System has been under development at Kennedy Space Center since 1973. A prototype system was developed and delivered to Marshall Space Flight Center for Solid Rocket Booster checkout in July 1976. The first production hardware arrived in late 1976. The System uses a distributed computer network for command and monitoring and is supported by a dual large scale computer system for 'off line' processing. A high level of automation is anticipated for Shuttle and Payload testing and launch operations to gain the advantages of short turnaround capability, repeatability of operations, and minimization of operations and maintenance (O&M) manpower. Learning how to efficiently apply the system is our current problem. We are searching for more effective ways to convey LPS system performance characteristics from the designer to a large number of users. Once we have done this, we can realize the advantages of LPS system design.

  2. ID card number detection algorithm based on convolutional neural network

    NASA Astrophysics Data System (ADS)

    Zhu, Jian; Ma, Hanjie; Feng, Jie; Dai, Leiyan

    2018-04-01

    In this paper, a new detection algorithm based on Convolutional Neural Network is presented in order to realize the fast and convenient ID information extraction in multiple scenarios. The algorithm uses the mobile device equipped with Android operating system to locate and extract the ID number; Use the special color distribution of the ID card, select the appropriate channel component; Use the image threshold segmentation, noise processing and morphological processing to take the binary processing for image; At the same time, the image rotation and projection method are used for horizontal correction when image was tilting; Finally, the single character is extracted by the projection method, and recognized by using Convolutional Neural Network. Through test shows that, A single ID number image from the extraction to the identification time is about 80ms, the accuracy rate is about 99%, It can be applied to the actual production and living environment.

  3. A Rapid Identification Method for Calamine Using Near-Infrared Spectroscopy Based on Multi-Reference Correlation Coefficient Method and Back Propagation Artificial Neural Network.

    PubMed

    Sun, Yangbo; Chen, Long; Huang, Bisheng; Chen, Keli

    2017-07-01

    As a mineral, the traditional Chinese medicine calamine has a similar shape to many other minerals. Investigations of commercially available calamine samples have shown that there are many fake and inferior calamine goods sold on the market. The conventional identification method for calamine is complicated, therefore as a result of the large scale of calamine samples, a rapid identification method is needed. To establish a qualitative model using near-infrared (NIR) spectroscopy for rapid identification of various calamine samples, large quantities of calamine samples including crude products, counterfeits and processed products were collected and correctly identified using the physicochemical and powder X-ray diffraction method. The NIR spectroscopy method was used to analyze these samples by combining the multi-reference correlation coefficient (MRCC) method and the error back propagation artificial neural network algorithm (BP-ANN), so as to realize the qualitative identification of calamine samples. The accuracy rate of the model based on NIR and MRCC methods was 85%; in addition, the model, which took comprehensive multiple factors into consideration, can be used to identify crude calamine products, its counterfeits and processed products. Furthermore, by in-putting the correlation coefficients of multiple references as the spectral feature data of samples into BP-ANN, a BP-ANN model of qualitative identification was established, of which the accuracy rate was increased to 95%. The MRCC method can be used as a NIR-based method in the process of BP-ANN modeling.

  4. Modifying sales summaries can aid forest products industries

    Treesearch

    G. B. Harpole

    1976-01-01

    This Note illustrates how a sales summary can be modified to separately identify changes in sales realization caused by changes in market prices and by changes in the product mix sold. With this information, a sales summary can become a helpful record to gage effects of past production and marketing decisions.

  5. The use of a new ecosystem services assessment tool, EPA H2O, for identifying, quantifying, and valuing ecosystem services production.

    EPA Science Inventory

    The task of estimating ecosystem service production and delivery deserves special attention. Assessment tools that incorporate both supply and delivery of ecosystem services are needed to better understand how ecosystem services production becomes realized benefits. Here, we de...

  6. QWIP and third-generation IR imagers

    NASA Astrophysics Data System (ADS)

    Costard, E.; Bois, Ph.; Marcadet, X.; Nedelcu, A.

    2005-10-01

    Standard GaAs/AlGaAs Quantum Well Infrared Photodetectors (QWIP) are from now seriously considered for the 3rd generation of IR imagers for military markets. Since 2002, the THALES Group has been manufacturing sensitive arrays using QWIP technology based on AsGa techniques through THALES Research and Technology Laboratory. This QWIP technology allows the realization of large staring arrays for Thermal Imagers (TI) working in the IR band III (8-12 μm). A review of the current QWIP products is presented. In the past researchers claimed many advantages of QWIPs. Uniformity was one of these and is the key parameter for the production start. By presenting our first results of a 640x512 LWIR FPA at a pitch of 20μm we also demonstrate that very high performances can be achieved even with small pixels which opens the field for the realization of usable and affordable megapixel FPAs. Another advantage widely claimed in the past for QWIPs was the so-called band-gap engineering and versatility of the III-V processing allowing the custom design of quantum structure to fulfill the requirements of specific applications like very long wavelength (VLWIR) or multispectral detection. In this presentation, we present the performances of our first 256x256 MWIR / LWIR two color FPA at a pitch of 25 μm, and also the current status of QWIPs for VLWIR arrays (>15μm).

  7. Fully industrialised single photon avalanche diodes

    NASA Astrophysics Data System (ADS)

    Pellegrini, S.; Rae, B.

    2017-05-01

    Single Photon Avalanche diodes (SPADs) were first realized more than five decades ago[1][1], and have now been industrialized for mass production in the 130 nm CMOS technology node by STMicroelectronics (STM). In this paper we present the latest STM SPAD with an excellent NIR photon detection probability (>5% at 850nm), a dark count rate median of 100 cps at room temperature and a low breakdown voltage of 14.2V. The dead time of the SPAD is approximately 25 ns, leading to a maximum count rate of 40 Mcps. Thanks to the 130 nm gate length of the CMOS technology used and the associated high digital gate density, complex digital signal processing can be implemented allowing fully integrated systems to be realized. The low bias required by the SPAD makes it possible for voltage generation to be achieved on-chip (e.g. charge pumped). We introduce our first generation time-of-flight system (VL6180) based on the STM SPAD technology, which is capable of ranging up to 60 cm in 60 ms. Ranging capabilities and accuracy are measured using a set of moving targets with reflectance of 5%, 17% and 88% in a fully automated test bed. To the best of our knowledge this was the first high volume SPAD-based device. To our knowledge this is the first time details of SPAD performance over production volumes and lifetime have been presented.

  8. Information transmission in bosonic memory channels using Gaussian matrix-product states as near-optimal symbols

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Schäfer, Joachim; Karpov, Evgueni; Cerf, Nicolas J.

    2014-12-04

    We seek for a realistic implementation of multimode Gaussian entangled states that can realize the optimal encoding for quantum bosonic Gaussian channels with memory. For a Gaussian channel with classical additive Markovian correlated noise and a lossy channel with non-Markovian correlated noise, we demonstrate the usefulness using Gaussian matrix-product states (GMPS). These states can be generated sequentially, and may, in principle, approximate well any Gaussian state. We show that we can achieve up to 99.9% of the classical Gaussian capacity with GMPS requiring squeezing parameters that are reachable with current technology. This may offer a way towards an experimental realization.

  9. A new pattern associative memory model for image recognition based on Hebb rules and dot product

    NASA Astrophysics Data System (ADS)

    Gao, Mingyue; Deng, Limiao; Wang, Yanjiang

    2018-04-01

    A great number of associative memory models have been proposed to realize information storage and retrieval inspired by human brain in the last few years. However, there is still much room for improvement for those models. In this paper, we extend a binary pattern associative memory model to accomplish real-world image recognition. The learning process is based on the fundamental Hebb rules and the retrieval is implemented by a normalized dot product operation. Our proposed model can not only fulfill rapid memory storage and retrieval for visual information but also have the ability on incremental learning without destroying the previous learned information. Experimental results demonstrate that our model outperforms the existing Self-Organizing Incremental Neural Network (SOINN) and Back Propagation Neuron Network (BPNN) on recognition accuracy and time efficiency.

  10. Spray forming -- Aluminum: Third annual report (Phase 2). Technical progress -- Summary

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kozarek, R.L.

    1998-04-20

    Commercial production of aluminum sheet and plate by spray atomization and deposition is a potentially attractive manufacturing alternative to conventional ingot metallurgy/hot-milling and to continuous casting processes because of reduced energy requirements and reduced cost. To realize the full potential of the technology, the Aluminum Company of America (Alcoa), under contract by the US Department of Energy, is investigating currently available state-of-the-art atomization devices to develop nozzle design concepts whose spray characteristics are tailored for continuous sheet production. This third technical progress report will summarize research and development work conducted during the period 1997 October through 1998 March. Included aremore » the latest optimization work on the Alcoa III nozzle, results of spray forming runs with 6111 aluminum alloy and preliminary rolling trials of 6111 deposits.« less

  11. The Research on Safety Management Information System of Railway Passenger Based on Risk Management Theory

    NASA Astrophysics Data System (ADS)

    Zhu, Wenmin; Jia, Yuanhua

    2018-01-01

    Based on the risk management theory and the PDCA cycle model, requirements of the railway passenger transport safety production is analyzed, and the establishment of the security risk assessment team is proposed to manage risk by FTA with Delphi from both qualitative and quantitative aspects. The safety production committee is also established to accomplish performance appraisal, which is for further ensuring the correctness of risk management results, optimizing the safety management business processes and improving risk management capabilities. The basic framework and risk information database of risk management information system of railway passenger transport safety are designed by Ajax, Web Services and SQL technologies. The system realizes functions about risk management, performance appraisal and data management, and provides an efficient and convenient information management platform for railway passenger safety manager.

  12. Automated optical assembly

    NASA Astrophysics Data System (ADS)

    Bala, John L.

    1995-08-01

    Automation and polymer science represent fundamental new technologies which can be directed toward realizing the goal of establishing a domestic, world-class, commercial optics business. Use of innovative optical designs using precision polymer optics will enable the US to play a vital role in the next generation of commercial optical products. The increased cost savings inherent in the utilization of optical-grade polymers outweighs almost every advantage of using glass for high volume situations. Optical designers must gain experience with combined refractive/diffractive designs and broaden their knowledge base regarding polymer technology beyond a cursory intellectual exercise. Implementation of a fully automated assembly system, combined with utilization of polymer optics, constitutes the type of integrated manufacturing process which will enable the US to successfully compete with the low-cost labor employed in the Far East, as well as to produce an equivalent product.

  13. Preparing synthetic biology for the world

    PubMed Central

    Moe-Behrens, Gerd H. G.; Davis, Rene; Haynes, Karmella A.

    2013-01-01

    Synthetic Biology promises low-cost, exponentially scalable products and global health solutions in the form of self-replicating organisms, or “living devices.” As these promises are realized, proof-of-concept systems will gradually migrate from tightly regulated laboratory or industrial environments into private spaces as, for instance, probiotic health products, food, and even do-it-yourself bioengineered systems. What additional steps, if any, should be taken before releasing engineered self-replicating organisms into a broader user space? In this review, we explain how studies of genetically modified organisms lay groundwork for the future landscape of biosafety. Early in the design process, biological engineers are anticipating potential hazards and developing innovative tools to mitigate risk. Here, we survey lessons learned, ongoing efforts to engineer intrinsic biocontainment, and how different stakeholders in synthetic biology can act to accomplish best practices for biosafety. PMID:23355834

  14. Integrated piezoelectric actuators in deep drawing tools

    NASA Astrophysics Data System (ADS)

    Neugebauer, R.; Mainda, P.; Drossel, W.-G.; Kerschner, M.; Wolf, K.

    2011-04-01

    The production of car body panels are defective in succession of process fluctuations. Thus the produced car body panel can be precise or damaged. To reduce the error rate, an intelligent deep drawing tool was developed at the Fraunhofer Institute for Machine Tools and Forming Technology IWU in cooperation with Audi and Volkswagen. Mechatronic components in a closed-loop control is the main differentiating factor between an intelligent and a conventional deep drawing tool. In correlation with sensors for process monitoring, the intelligent tool consists of piezoelectric actuators to actuate the deep drawing process. By enabling the usage of sensors and actuators at the die, the forming tool transform to a smart structure. The interface between sensors and actuators will be realized with a closed-loop control. The content of this research will present the experimental results with the piezoelectric actuator. For the analysis a production-oriented forming tool with all automotive requirements were used. The disposed actuators are monolithic multilayer actuators of the piezo injector system. In order to achieve required force, the actuators are combined in a cluster. The cluster is redundant and economical. In addition to the detailed assembly structures, this research will highlight intensive analysis with the intelligent deep drawing tool.

  15. Thermochemical recovery of heat contained in flue gases by means of bioethanol conversion

    NASA Astrophysics Data System (ADS)

    Pashchenko, D. I.

    2013-06-01

    In the present paper consideration is being given to the use of bioethanol in the schemes of thermochemical recovery of heat contained in exit flue gases. Schematic diagrams illustrate the realization of thermochemical heat recovery by implementing ethanol steam conversion and conversion of ethanol by means of products of its complete combustion. The feasibility of attaining a high degree of recovery of heat contained in flue gases at the moderate temperature (up to 450°C) of combustion components is demonstrated in the example of the energy balance of the system for thermochemical heat recovery. The simplified thermodynamic analysis of the process of ethanol steam conversion was carried out in order to determine possible ranges of variation of process variables (temperature, pressure, composition) of a reaction mixture providing the efficient heat utilization. It was found that at the temperature above 600 K the degree of ethanol conversion is near unity. The equilibrium composition of products of reaction of ethanol steam conversion has been identified for different temperatures at which the process occurs at the ratio H2O/EtOH = 1 and at the pressure of 0.1 MPa. The obtained results of calculation agree well with the experimental data.

  16. Automation and Upgrade of Thermal System for Large 38-Year-Young Test Facility

    NASA Technical Reports Server (NTRS)

    Webb, Andrew T.; Powers, Edward I. (Technical Monitor)

    2000-01-01

    The Goddard Space Flight Center's Space Environment Simulator (SES) facility has been improved by the upgrade of its thermal control hardware and software. This paper describes the preliminary design process, funding constraints, and the proposed enhancements as well as the installation details, the testing difficulties, and the overall benefits realized from this upgrade. The preliminary design process was discussed in a paper presented in October 1996 and will be recapped in this paper to provide background and comparison to actual product. Structuring the procurement process to match the funding constraints allowed Goddard to enhance its capabilities in an environment of reduced budgets. The installation of the new system into a location that has been occupied for over 38 years was one of the driving design factors for the size of the equipment. The installation was completed on time and under budget. The tuning of the automatic sequences for the new thermal system to the existing shroud system required more time and ultimately presented some setbacks to the vendor and the final completion of the system. However, the end product and its benefits to Goddard's thermal vacuum test portfolio will carry the usefulness of this facility well into the next century.

  17. Automation and Upgrade of Thermal System for Large 38-Year Young Test Facility

    NASA Technical Reports Server (NTRS)

    Webb, Andrew

    2000-01-01

    The Goddard Space Flight Center's Space Environment Simulator (SES) facility has been improved by the upgrade of its thermal control hardware and software. This paper describes the preliminary design process, funding constraints, and the proposed enhancements as well as the installation details, the testing difficulties, and the overall benefits realized from this upgrade. The preliminary design process was discussed in a paper presented in October 1996 and will be recapped in this paper to provide background and comparison to actual product. Structuring the procurement process to match the funding constraints allowed Goddard to enhance its capabilities in an environment of reduced budgets. The installation of the new system into a location that has been occupied for over 38-years was one of the driving design factors for the size of the equipment. The installation was completed on-time and under budget. The tuning of the automatic sequences for the new thermal system to the existing shroud system required more time and ultimately presented some setbacks to the vendor and the final completion of the system. However, the end product and its benefits to Goddard's thermal vacuum test portfolio will carry the usefulness of this facility well into the next century.

  18. Integrated operation of continuous chromatography and biotransformations for the generic high yield production of fine chemicals.

    PubMed

    Bechtold, Matthias; Makart, Stefan; Heinemann, Matthias; Panke, Sven

    2006-06-25

    The rapid progress in biocatalysis in the identification and development of enzymes over the last decade has enormously enlarged the chemical reaction space that can be addressed not only in research applications, but also on industrial scale. This enables us to consider even those groups of reactions that are very promising from a synthetic point of view, but suffer from drawbacks on process level, such as an unfavourable position of the reaction equilibrium. Prominent examples stem from the aldolase-catalyzed enantioselective carbon-carbon bond forming reactions, reactions catalyzed by isomerising enzymes, and reactions that are kinetically controlled. On the other hand, continuous chromatography concepts such as the simulating moving bed technology have matured and are increasingly realized on industrial scale for the efficient separation of difficult compound mixtures - including enantiomers - with unprecedented efficiency. We propose that coupling of enzyme reactor and continuous chromatography is a very suitable and potentially generic process concept to address the thermodynamic limitations of a host of promising biotransformations. This way, it should be possible to establish novel in situ product recovery processes of unprecedented efficiency and selectivity that represent a feasible way to recruit novel biocatalysts to the industrial portfolio.

  19. Information flow analysis and Petri-net-based modeling for welding flexible manufacturing cell

    NASA Astrophysics Data System (ADS)

    Qiu, T.; Chen, Shanben; Wang, Y. T.; Wu, Lin

    2000-10-01

    Due to the development of advanced manufacturing technology and the introduction of Smart-Manufacturing notion in the field of modern industrial production, welding flexible manufacturing system (WFMS) using robot technology has become the inevitable developing direction on welding automation. In WFMS process, the flexibility for different welding products and the realizing on corresponding welding parameters control are the guarantees for welding quality. Based on a new intelligent arc-welding flexible manufacturing cell (WFMC), the system structure and control policies are studied in this paper. Aiming at the different information flows among every subsystem and central monitoring computer in this WFMC, Petri net theory is introduced into the process of welding manufacturing. With its help, a discrete control model of WFMC has been constructed, in which the system status is regarded as place and the control process is regarded as transition. Moreover, grounded on automation Petri net principle, the judging and utilizing of information obtained from welding sensors are imported into net structure, which extends the traditional Petri net concepts. The control model and policies researched in this paper have established foundation for further intelligent real-time control on WFMC and WFMS.

  20. 16 CFR 1031.16 - Purpose and scope.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION GENERAL COMMISSION PARTICIPATION AND COMMISSION... and scope. (a) This subpart sets forth the Consumer Product Safety Commission's criteria and... development bodies. (b) The Commission realizes there are advantages and benefits afforded by greater public...

  1. Strategy of Construction and Demolition Waste Management after Chemical Industry Facilities Removal

    NASA Astrophysics Data System (ADS)

    Tashkinova, I. N.; Batrakova, G. M.; Vaisman, Ya I.

    2017-06-01

    Mixed waste products are generated in the process of irrelevant industrial projects’ removal if conventional techniques of their demolition and dismantling are applied. In Russia the number of unused chemical industry facilities including structures with high rate of wear is growing. In removing industrial buildings and production shops it is used conventional techniques of demolition and dismantling in the process of which mixed waste products are generated. The presence of hazardous chemicals in these wastes makes difficulties for their use and leads to the increasing volume of unutilized residues. In the process of chemical industry facilities’ removal this fact takes on special significance as a high level of hazardous chemicals in the waste composition demands for the realization of unprofitable measures aimed at ensuring environmental and industrial safety. The proposed strategy of managing waste originated from the demolition and dismantling of chemical industry facilities is based on the methodology of industrial metabolism which allows identifying separate material flows of recycled, harmful and ballast components, performing separate collection of components during removal and taking necessary preventive measures. This strategy has been tested on the aniline synthesis plant being in the process of removal. As a result, a flow of 10 wt. %, subjected to decontamination, was isolated from the total volume of construction and demolition waste (C&D waste). The considered approach allowed using the resource potential of more than 80wt. % of waste and minimizing the disposed waste volume.

  2. The research of laser marking control technology

    NASA Astrophysics Data System (ADS)

    Zhang, Qiue; Zhang, Rong

    2009-08-01

    In the area of Laser marking, the general control method is insert control card to computer's mother board, it can not support hot swap, it is difficult to assemble or it. Moreover, the one marking system must to equip one computer. In the system marking, the computer can not to do the other things except to transmit marking digital information. Otherwise it can affect marking precision. Based on traditional control methods existed some problems, introduced marking graphic editing and digital processing by the computer finish, high-speed digital signal processor (DSP) control marking the whole process. The laser marking controller is mainly contain DSP2812, digital memorizer, DAC (digital analog converting) transform unit circuit, USB interface control circuit, man-machine interface circuit, and other logic control circuit. Download the marking information which is processed by computer to U disk, DSP read the information by USB interface on time, then processing it, adopt the DSP inter timer control the marking time sequence, output the scanner control signal by D/A parts. Apply the technology can realize marking offline, thereby reduce the product cost, increase the product efficiency. The system have good effect in actual unit markings, the marking speed is more quickly than PCI control card to 20 percent. It has application value in practicality.

  3. Dairy in a sustainable diet: a question of balance.

    PubMed

    van Hooijdonk, Toon; Hettinga, Kasper

    2015-08-01

    The demand for dairy products is growing rapidly, especially in emerging markets. Dairy products are nutrient rich and, therefore, an important food group for ensuring nutrient security in the future. In many countries, dairy contributes significantly to nutrient intake. Meta-analyses have shown that consumption of dairy may reduce the risk of chronic diseases and thereby lower healthcare costs. Milk production and processing contribute to greenhouse gas emissions, estimated at 2.7% (cradle-to-retail) of the world's total. Evaluating the position of dairy in the diet should take into account the impact of both nutritional and environmental factors. Local conditions are also important; in many parts of the world, the cow is an efficient converter of human-inedible resources into nutrient-dense food. Increased productivity of cows is a decisive factor in realizing sufficient milk production with optimal resource efficiency and minimal greenhouse gas emission. Models that optimize total diets, rather than individual food products, for their nutritional and environmental impact are the preferred approach for developing realistic alternative consumption strategies. © The Author(s) 2015. Published by Oxford University Press on behalf of the International Life Sciences Institute. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  4. Estimating the Celestial Reference Frame via Intra-Technique Combination

    NASA Astrophysics Data System (ADS)

    Iddink, Andreas; Artz, Thomas; Halsig, Sebastian; Nothnagel, Axel

    2016-12-01

    One of the primary goals of Very Long Baseline Interferometry (VLBI) is the determination of the International Celestial Reference Frame (ICRF). Currently the third realization of the internationally adopted CRF, the ICRF3, is under preparation. In this process, various optimizations are planned to realize a CRF that does not benefit only from the increased number of observations since the ICRF2 was published. The new ICRF can also benefit from an intra-technique combination as is done for the Terrestrial Reference Frame (TRF). Here, we aim at estimating an optimized CRF by means of an intra-technique combination. The solutions are based on the input to the official combined product of the International VLBI Service for Geodesy and Astrometry (IVS), also providing the radio source parameters. We discuss the differences in the setup using a different number of contributions and investigate the impact on TRF and CRF as well as on the Earth Orientation Parameters (EOPs). Here, we investigate the differences between the combined CRF and the individual CRFs from the different analysis centers.

  5. Implementation of Quantum Private Queries Using Nuclear Magnetic Resonance

    NASA Astrophysics Data System (ADS)

    Wang, Chuan; Hao, Liang; Zhao, Lian-Jie

    2011-08-01

    We present a modified protocol for the realization of a quantum private query process on a classical database. Using one-qubit query and CNOT operation, the query process can be realized in a two-mode database. In the query process, the data privacy is preserved as the sender would not reveal any information about the database besides her query information, and the database provider cannot retain any information about the query. We implement the quantum private query protocol in a nuclear magnetic resonance system. The density matrix of the memory registers are constructed.

  6. Realization of planning design of mechanical manufacturing system by Petri net simulation model

    NASA Astrophysics Data System (ADS)

    Wu, Yanfang; Wan, Xin; Shi, Weixiang

    1991-09-01

    Planning design is to work out a more overall long-term plan. In order to guarantee a mechanical manufacturing system (MMS) designed to obtain maximum economical benefit, it is necessary to carry out a reasonable planning design for the system. First, some principles on planning design for MMS are introduced. Problems of production scheduling and their decision rules for computer simulation are presented. Realizable method of each production scheduling decision rule in Petri net model is discussed. Second, the solution of conflict rules for conflict problems during running Petri net is given. Third, based on the Petri net model of MMS which includes part flow and tool flow, according to the principle of minimum event time advance, a computer dynamic simulation of the Petri net model, that is, a computer dynamic simulation of MMS, is realized. Finally, the simulation program is applied to a simulation exmple, so the scheme of a planning design for MMS can be evaluated effectively.

  7. Study of a novel electromagnetic liquid argon calorimeter — the TGT

    NASA Astrophysics Data System (ADS)

    Berger, C.; Braunschweig, W.; Geulig, E.; Schöntag, M.; Siedling, R.; Wlochal, M.; Putzer, A.; Wotschack, J.; Cheplakov, A.; Feshchenko, A.; Kazarinov, M.; Kukhtin, V.; Ladygin, E.; Obudovskij, V.; Geweniger, C.; Hanke, P.; Kluge, E.-E.; Krause, J.; Schmidt, M.; Stenzel, H.; Tittel, K.; Wunsch, M.; Zerwas, D.; Bruncko, D.; Jusko, A.; Kocper, B.; Lupták, M.; Aderholz, M.; Bán, J.; Brettel, H.; Dydak, F.; Fent, J.; Frey, H.; Huber, J.; Jakobs, K.; Kiesling, C.; Kiryunin, A. E.; Oberlack, H.; Ribarics, P.; Schacht, P.; Stiegler, U.; Bogolyubsky, M. Y.; Buyanov, O. V.; Chekulaev, S. V.; Kurchaninov, L. L.; Levitsky, M. S.; Maximov, V. V.; Minaenko, A. A.; Moiseev, A. M.; Semenov, P. A.; Tikhonov, V. V.; Straumann, U.

    1995-02-01

    The concept and the basic design of a fast, highly granular and compact electromagnetic liquid argon calorimeter are described. This novel calorimeter offers uniform energy response and constant energy resolution independent of the production angle of an impinging particle and of its impact position at the calorimeter. An example of a calorimeter with full rapidity coverage in an application in a collider detector is given. An important aspect of the concept is the electronics for fast signal processing matched to the short charge collection time. We report on the experience with the realization of a prototype calorimeter module and on its performance in a testbeam exposure.

  8. Integrated Optical Circuit Engineering For Optical Fiber Gyrocopes

    NASA Astrophysics Data System (ADS)

    Bristow, Julian P.; We, Albert C.; Keur, M.; Lukas, Greg; Ott, Daniel M...; Sriram, S.

    1988-03-01

    Fiber optic gyroscopes are of interest for low-cost, high performance rotation sensors. Integrated optical implementations of the processing optics offer the hope of mass-production, and associated cost reductions. The development of a suitable integrated optical system has been reported by other authors at a wavelength of 850nm [1]. Despite strong technical advantages at 1.3μm wavelength [2], no results have yet appeared. This wavelength is preferred for telecommunications applications applications, thus significantly reduced fiber costs may be realized. Lithium niobate is relatively immune from the photorefractive effect at this wavelength, whereas it is not at at 850nm [3].

  9. Optimization research on the concentration field of NO in selective catalytic reduction flue gas denitration system

    NASA Astrophysics Data System (ADS)

    Zheng, Qingyu; Zhang, Guoqiang; Che, Kai; Shao, Shikuan; Li, Yanfei

    2017-08-01

    Taking 660 MW generator unit denitration system as a study object, an optimization and adjustment method shall be designed to control ammonia slip, i.e. adjust ammonia injection system based on NO concentration distribution at inlet/outlet of the denitration system to make the injected ammonia distribute evenly. The results shows that, this method can effectively improve NO concentration distribution at outlet of the denitration system and decrease ammonia injection amount and ammonia slip concentration. Reduce adverse impact of SCR denitration process on the air preheater to realize safe production by guaranteeing that NO discharge shall reach the standard.

  10. Automated seamline detection along skeleton for remote sensing image mosaicking

    NASA Astrophysics Data System (ADS)

    Zhang, Hansong; Chen, Jianyu; Liu, Xin

    2015-08-01

    The automatic generation of seamline along the overlap region skeleton is a concerning problem for the mosaicking of Remote Sensing(RS) images. Along with the improvement of RS image resolution, it is necessary to ensure rapid and accurate processing under complex conditions. So an automated seamline detection method for RS image mosaicking based on image object and overlap region contour contraction is introduced. By this means we can ensure universality and efficiency of mosaicking. The experiments also show that this method can select seamline of RS images with great speed and high accuracy over arbitrary overlap regions, and realize RS image rapid mosaicking in surveying and mapping production.

  11. Atomic vapor quantum memory for a photonic polarization qubit.

    PubMed

    Cho, Young-Wook; Kim, Yoon-Ho

    2010-12-06

    We report an experimental realization of an atomic vapor quantum memory for the photonic polarization qubit. The performance of the quantum memory for the polarization qubit, realized with electromagnetically-induced transparency in two spatially separated ensembles of warm Rubidium atoms in a single vapor cell, has been characterized with quantum process tomography. The process fidelity better than 0.91 for up to 16 μs of storage time has been achieved.

  12. Development of a Low-Cost UAV Doppler Radar Data System

    NASA Technical Reports Server (NTRS)

    Knuble, Joseph; Li, Lihua; Heymsfield, Gerry

    2005-01-01

    A viewgraph presentation on the design of a low cost unmanned aerial vehicle (UAV) doppler radar data system is presented. The topics include: 1) Science and Mission Background; 2) Radar Requirements and Specs; 3) Radar Realization: RF System; 4) Processing of RF Signal; 5) Data System Design Process; 6) Can We Remove the DSP? 7) Determining Approximate Speed Requirements; 8) Radar Realization: Data System; 9) Data System Operation; and 10) Results.

  13. Synthetic schlieren—application to the visualization and characterization of air convection

    NASA Astrophysics Data System (ADS)

    Taberlet, Nicolas; Plihon, Nicolas; Auzémery, Lucile; Sautel, Jérémy; Panel, Grégoire; Gibaud, Thomas

    2018-05-01

    Synthetic schlieren is a digital image processing optical method relying on the variation of optical index to visualize the flow of a transparent fluid. In this article, we present a step-by-step, easy-to-implement and affordable experimental realization of this technique. The method is applied to air convection caused by a warm surface. We show that the velocity of rising convection plumes can be linked to the temperature of the warm surface and propose a simple physical argument to explain this dependence. Moreover, using this method, one can reveal the tenuous convection plumes rising from one’s hand, a phenomenon invisible to the naked eye. This spectacular result may help students to realize the power of careful data acquisition combined with astute image processing techniques. This spectacular result may help students to realize the power of careful data acquisition combined with astute image processing techniques (refer to the video abstract).

  14. Three-Dimensional Reconstruction of the Virtual Plant Branching Structure Based on Terrestrial LIDAR Technologies and L-System

    NASA Astrophysics Data System (ADS)

    Gong, Y.; Yang, Y.; Yang, X.

    2018-04-01

    For the purpose of extracting productions of some specific branching plants effectively and realizing its 3D reconstruction, Terrestrial LiDAR data was used as extraction source of production, and a 3D reconstruction method based on Terrestrial LiDAR technologies combined with the L-system was proposed in this article. The topology structure of the plant architectures was extracted using the point cloud data of the target plant with space level segmentation mechanism. Subsequently, L-system productions were obtained and the structural parameters and production rules of branches, which fit the given plant, was generated. A three-dimensional simulation model of target plant was established combined with computer visualization algorithm finally. The results suggest that the method can effectively extract a given branching plant topology and describes its production, realizing the extraction of topology structure by the computer algorithm for given branching plant and also simplifying the extraction of branching plant productions which would be complex and time-consuming by L-system. It improves the degree of automation in the L-system extraction of productions of specific branching plants, providing a new way for the extraction of branching plant production rules.

  15. Review of integrated digital systems: evolution and adoption

    NASA Astrophysics Data System (ADS)

    Fritz, Lawrence W.

    The factors that are influencing the evolution of photogrammetric and remote sensing technology to transition into fully integrated digital systems are reviewed. These factors include societal pressures for new, more timely digital products from the Spatial Information Sciencesand the adoption of rapid technological advancements in digital processing hardware and software. Current major developments in leading government mapping agencies of the USA, such as the Digital Production System (DPS) modernization programme at the Defense Mapping Agency, and the Automated Nautical Charting System II (ANCS-II) programme and Integrated Digital Photogrammetric Facility (IDPF) at NOAA/National Ocean Service, illustrate the significant benefits to be realized. These programmes are examples of different levels of integrated systems that have been designed to produce digital products. They provide insights to the management complexities to be considered for very large integrated digital systems. In recognition of computer industry trends, a knowledge-based architecture for managing the complexity of the very large spatial information systems of the future is proposed.

  16. Agricultural Model for the Nile Basin Decision Support System

    NASA Astrophysics Data System (ADS)

    van der Bolt, Frank; Seid, Abdulkarim

    2014-05-01

    To analyze options for increasing food supply in the Nile basin the Nile Agricultural Model (AM) was developed. The AM includes state-of-the-art descriptions of biophysical, hydrological and economic processes and realizes a coherent and consistent integration of hydrology, agronomy and economics. The AM covers both the agro-ecological domain (water, crop productivity) and the economic domain (food supply, demand, and trade) and allows to evaluate the macro-economic and hydrological impacts of scenarios for agricultural development. Starting with the hydrological information from the NileBasin-DSS the AM calculates the available water for agriculture, the crop production and irrigation requirements with the FAO-model AquaCrop. With the global commodity trade model MAGNET scenarios for land development and conversion are evaluated. The AM predicts consequences for trade, food security and development based on soil and water availability, crop allocation, food demand and food policy. The model will be used as a decision support tool to contribute to more productive and sustainable agriculture in individual Nile countries and the whole region.

  17. The Research and Implementation of Vehicle Bluetooth Hands-free Devices Key Parameters Downloading Algorithm

    NASA Astrophysics Data System (ADS)

    Zhang, Xiao-bo; Wang, Zhi-xue; Li, Jian-xin; Ma, Jian-hui; Li, Yang; Li, Yan-qiang

    In order to facilitate Bluetooth function realization and information can be effectively tracked in the process of production, the vehicle Bluetooth hands-free devices need to download such key parameters as Bluetooth address, CVC license and base plate numbers, etc. Therefore, it is the aim to search simple and effective methods to download parameters for each vehicle Bluetooth hands-free device, and to control and record the use of parameters. In this paper, by means of Bluetooth Serial Peripheral Interface programmer device, the parallel port is switched to SPI. The first step is to download parameters is simulating SPI with the parallel port. To perform SPI function, operating the parallel port in accordance with the SPI timing. The next step is to achieve SPI data transceiver functions according to the programming parameters of options. Utilizing the new method, downloading parameters is fast and accurate. It fully meets vehicle Bluetooth hands-free devices production requirements. In the production line, it has played a large role.

  18. Application of decentralized cooperative problem solving in dynamic flexible scheduling

    NASA Astrophysics Data System (ADS)

    Guan, Zai-Lin; Lei, Ming; Wu, Bo; Wu, Ya; Yang, Shuzi

    1995-08-01

    The object of this study is to discuss an intelligent solution to the problem of task-allocation in shop floor scheduling. For this purpose, the technique of distributed artificial intelligence (DAI) is applied. Intelligent agents (IAs) are used to realize decentralized cooperation, and negotiation is realized by using message passing based on the contract net model. Multiple agents, such as manager agents, workcell agents, and workstation agents, make game-like decisions based on multiple criteria evaluations. This procedure of decentralized cooperative problem solving makes local scheduling possible. And by integrating such multiple local schedules, dynamic flexible scheduling for the whole shop floor production can be realized.

  19. Cheminformatics and Computational Chemistry: A Powerful ...

    EPA Pesticide Factsheets

    The registration of new chemicals under the Toxicological Substances Control Act (TSCA) and new pesticides under the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) requires knowledge of the process science underlying the transformation of organic chemicals in natural ecosystems. The purpose of this presentation is to demonstrate how cheminformatics using chemical terms language in combination with the output of physicochemical property calculators can be employed to encode this knowledge and make it available to the appropriate decision makers. The encoded process science is realized through the execution of reaction libraries in simulators such as EPA’s Chemical Transformation Simulator (CTS). In support of the CTS, reaction libraries have or are currently being developed for a number of transformation processes including hydrolysis, abiotic reduction, photolysis and disinfection by-product formation. Examples of how the process science available in the peer-reviewed literature is being encoded will be presented. Presented at the 252nd American Chemical Society National Meeting:Aquatic Chemistry: Symposium in Honor of Professor Alan T. Stone

  20. Reflections on using biographical approaches in end-of-life care: dignity therapy as example.

    PubMed

    Lindqvist, Olav; Threlkeld, Guinever; Street, Annette F; Tishelman, Carol

    2015-01-01

    The therapeutic potential of nonpharmacologic interventions using biographical approaches at the end of life (EoL) is being increasingly recognized, but less attention is paid to processes impeding realization of this potential. In this article, Swedish and Australian researchers reflect on and problematize experiences using one biographical approach, dignity therapy (DT), in EoL care in Sweden. We use this as an example, focusing on critical examination of the process of applying DT in practice, examining frictions experienced in recruiting participants, collecting the data, and creating a biography. We discuss issues regarding agency, which became evident in the recruitment process and choices made about participation, and the power differentials manifested in the interactive process of eliciting stories and crafting them into a final product. We also raise salient questions about how research and practice with biographical approaches in EoL care might better build on and further existing knowledge to better reflect the complexities of everyday life. © The Author(s) 2014.

  1. Analysis of Realized Volatility for Nikkei Stock Average on the Tokyo Stock Exchange

    NASA Astrophysics Data System (ADS)

    Takaishi, Tetsuya; Watanabe, Toshiaki

    2016-04-01

    We calculate realized volatility of the Nikkei Stock Average (Nikkei225) Index on the Tokyo Stock Exchange and investigate the return dynamics. To avoid the bias on the realized volatility from the non-trading hours issue we calculate realized volatility separately in the two trading sessions, i.e. morning and afternoon, of the Tokyo Stock Exchange and find that the microstructure noise decreases the realized volatility at small sampling frequency. Using realized volatility as a proxy of the integrated volatility we standardize returns in the morning and afternoon sessions and investigate the normality of the standardized returns by calculating variance, kurtosis and 6th moment. We find that variance, kurtosis and 6th moment are consistent with those of the standard normal distribution, which indicates that the return dynamics of the Nikkei Stock Average are well described by a Gaussian random process with time-varying volatility.

  2. Software designs of image processing tasks with incremental refinement of computation.

    PubMed

    Anastasia, Davide; Andreopoulos, Yiannis

    2010-08-01

    Software realizations of computationally-demanding image processing tasks (e.g., image transforms and convolution) do not currently provide graceful degradation when their clock-cycles budgets are reduced, e.g., when delay deadlines are imposed in a multitasking environment to meet throughput requirements. This is an important obstacle in the quest for full utilization of modern programmable platforms' capabilities since worst-case considerations must be in place for reasonable quality of results. In this paper, we propose (and make available online) platform-independent software designs performing bitplane-based computation combined with an incremental packing framework in order to realize block transforms, 2-D convolution and frame-by-frame block matching. The proposed framework realizes incremental computation: progressive processing of input-source increments improves the output quality monotonically. Comparisons with the equivalent nonincremental software realization of each algorithm reveal that, for the same precision of the result, the proposed approach can lead to comparable or faster execution, while it can be arbitrarily terminated and provide the result up to the computed precision. Application examples with region-of-interest based incremental computation, task scheduling per frame, and energy-distortion scalability verify that our proposal provides significant performance scalability with graceful degradation.

  3. Environmental impact associated with activated carbon preparation from olive-waste cake via life cycle assessment.

    PubMed

    Hjaila, K; Baccar, R; Sarrà, M; Gasol, C M; Blánquez, P

    2013-11-30

    The life cycle assessment (LCA) environmental tool was implemented to quantify the potential environmental impacts associated with the activated carbon (AC) production process from olive-waste cakes in Tunisia. On the basis of laboratory investigations for AC preparation, a flowchart was developed and the environmental impacts were determined. The LCA functional unit chosen was the production of 1 kg of AC from by-product olive-waste cakes. The results showed that impregnation using H3PO4 presented the highest environmental impacts for the majority of the indicators tested: acidification potential (62%), eutrophication (96%), ozone depletion potential (44%), human toxicity (64%), fresh water aquatic ecotoxicity (90%) and terrestrial ecotoxicity (92%). One of the highest impacts was found to be the global warming potential (11.096 kg CO2 eq/kg AC), which was equally weighted between the steps involving impregnation, pyrolysis, and drying the washed AC. The cumulative energy demand of the AC production process from the by-product olive-waste cakes was 167.63 MJ contributed by impregnation, pyrolysis, and drying the washed AC steps. The use of phosphoric acid and electricity in the AC production were the main factors responsible for the majority of the impacts. If certain modifications are incorporated into the AC production, such as implementing synthesis gas recovery and reusing it as an energy source and recovery of phosphoric acid after AC washing, additional savings could be realized, and environmental impacts could be minimized. Copyright © 2013 Elsevier Ltd. All rights reserved.

  4. Electrolysis of metal oxides in MgCl2 based molten salts with an inert graphite anode.

    PubMed

    Yuan, Yating; Li, Wei; Chen, Hualin; Wang, Zhiyong; Jin, Xianbo; Chen, George Z

    2016-08-15

    Electrolysis of solid metal oxides has been demonstrated in MgCl2-NaCl-KCl melt at 700 °C taking the electrolysis of Ta2O5 as an example. Both the cathodic and anodic processes have been investigated using cyclic voltammetry, and potentiostatic and constant voltage electrolysis, with the cathodic products analysed by XRD and SEM and the anodic products by GC. Fast electrolysis of Ta2O5 against a graphite anode has been realized at a cell voltage of 2 V, or a total overpotential of about 400 mV. The energy consumption was about 1 kW h kgTa(-1) with a nearly 100% Ta recovery. The cathodic product was nanometer Ta powder with sizes of about 50 nm. The main anodic product was Cl2 gas, together with about 1 mol% O2 gas and trace amounts of CO. The graphite anode was found to be an excellent inert anode. These results promise an environmentally-friendly and energy efficient method for metal extraction by electrolysis of metal oxides in MgCl2 based molten salts.

  5. A CBR-Based and MAHP-Based Customer Value Prediction Model for New Product Development

    PubMed Central

    Zhao, Yu-Jie; Luo, Xin-xing; Deng, Li

    2014-01-01

    In the fierce market environment, the enterprise which wants to meet customer needs and boost its market profit and share must focus on the new product development. To overcome the limitations of previous research, Chan et al. proposed a dynamic decision support system to predict the customer lifetime value (CLV) for new product development. However, to better meet the customer needs, there are still some deficiencies in their model, so this study proposes a CBR-based and MAHP-based customer value prediction model for a new product (C&M-CVPM). CBR (case based reasoning) can reduce experts' workload and evaluation time, while MAHP (multiplicative analytic hierarchy process) can use actual but average influencing factor's effectiveness in stimulation, and at same time C&M-CVPM uses dynamic customers' transition probability which is more close to reality. This study not only introduces the realization of CBR and MAHP, but also elaborates C&M-CVPM's three main modules. The application of the proposed model is illustrated and confirmed to be sensible and convincing through a stimulation experiment. PMID:25162050

  6. Modeling Design Iteration in Product Design and Development and Its Solution by a Novel Artificial Bee Colony Algorithm

    PubMed Central

    2014-01-01

    Due to fierce market competition, how to improve product quality and reduce development cost determines the core competitiveness of enterprises. However, design iteration generally causes increases of product cost and delays of development time as well, so how to identify and model couplings among tasks in product design and development has become an important issue for enterprises to settle. In this paper, the shortcomings existing in WTM model are discussed and tearing approach as well as inner iteration method is used to complement the classic WTM model. In addition, the ABC algorithm is also introduced to find out the optimal decoupling schemes. In this paper, firstly, tearing approach and inner iteration method are analyzed for solving coupled sets. Secondly, a hybrid iteration model combining these two technologies is set up. Thirdly, a high-performance swarm intelligence algorithm, artificial bee colony, is adopted to realize problem-solving. Finally, an engineering design of a chemical processing system is given in order to verify its reasonability and effectiveness. PMID:25431584

  7. Production of xylanolytic enzymes by Aspergillus terricola in stirred tank and airlift tower loop bioreactors.

    PubMed

    Michelin, Michele; Polizeli, Maria de Lourdes Teixeira de Moraes; Silva, Daniel Pereira da; Ruzene, Denise Santos; Vicente, António Augusto; Jorge, João Atílio; Terenzi, Héctor Francisco; Teixeira, José António

    2011-12-01

    Fungi producing high xylanase levels have attracted considerable attention because of their potential industrial applications. Batch cultivations of Aspergillus terricola fungus were evaluated in stirred tank and airlift bioreactors, by using wheat bran particles suspended in the cultivation medium as substrate for xylanase and β-xylosidase production. In the stirred tank bioreactor, in physical conditions of 30°C, 300 rpm, and aeration of 1 vvm (1 l min⁻¹), with direct inoculation of fungal spores, 7,475 U l⁻¹ xylanase was obtained after 36 h of operation, remaining constant after 24 h. In the absence of air injection in the stirred tank reactor, limited xylanase production was observed (final concentration 740 U l⁻¹). When the fermentation process was realized in the airlift bioreactor, xylanase production was higher than that observed in the stirred tank bioreactor, being 9,265 U l⁻¹ at 0.07 vvm (0.4 l min⁻¹) and 12,845 U l⁻¹ at 0.17 vvm (1 l min⁻¹) aeration rate.

  8. A CBR-based and MAHP-based customer value prediction model for new product development.

    PubMed

    Zhao, Yu-Jie; Luo, Xin-xing; Deng, Li

    2014-01-01

    In the fierce market environment, the enterprise which wants to meet customer needs and boost its market profit and share must focus on the new product development. To overcome the limitations of previous research, Chan et al. proposed a dynamic decision support system to predict the customer lifetime value (CLV) for new product development. However, to better meet the customer needs, there are still some deficiencies in their model, so this study proposes a CBR-based and MAHP-based customer value prediction model for a new product (C&M-CVPM). CBR (case based reasoning) can reduce experts' workload and evaluation time, while MAHP (multiplicative analytic hierarchy process) can use actual but average influencing factor's effectiveness in stimulation, and at same time C&M-CVPM uses dynamic customers' transition probability which is more close to reality. This study not only introduces the realization of CBR and MAHP, but also elaborates C&M-CVPM's three main modules. The application of the proposed model is illustrated and confirmed to be sensible and convincing through a stimulation experiment.

  9. Large Area Microencapsulated Reflective Guest-Host Liquid Crystal Displays and Their Applications

    NASA Astrophysics Data System (ADS)

    Nakai, Yutaka; Tanaka, Masao; Enomoto, Shintaro; Iwanaga, Hiroki; Hotta, Aira; Kobayashi, Hitoshi; Oka, Toshiyuki; Kizaki, Yukio; Kidzu, Yuko; Naito, Katsuyuki

    2002-07-01

    We have developed reflective liquid crystal displays using microencapsulated guest-host liquid crystals, whose size was sufficiently large for viewing documents. A high-brightness image can be realized because there is no need for polarizers. Easy fabrication processes, consisting of screen-printing of microencapsulated liquid crystal and film adhesion, have enabled the realization of thinner and lighter cell structures. It has been confirmed that the display is tolerant of the pressures to which it would be subject in actual use. The optimization of fabrication processes has enabled the realization of reflectance uniformity in the display area and reduction of the driving voltage. Our developed display is suitable for portable information systems, such as electronic book applications.

  10. Improving patient care by making small sustainable changes: a cardiac telemetry unit's experience.

    PubMed

    Braaten, Jane S; Bellhouse, Dorothy E

    2007-01-01

    With the introduction of each new drug, technology, and regulation, the processes of care become more complicated, creating an elaborate set of procedures connecting various hospital units and departments. Using methods of Adaptive Design and the Toyota Production System, a nursing unit redesigned work systems to achieve sustainable improvements in productivity, staff and patient satisfaction, and quality outcomes. The first hurdle of redesign was identifying problems, to which staff had become so accustomed with various work arounds that they had trouble seeing the process bottlenecks. Once the staff identified problems, they assumed they could solve the problem because they assumed they knew the causes. Utilizing root cause analysis, asking, "why, why, why," was essential to unearthing the true cause of a problem. Similarly, identifying solutions that were simple and low cost was an essential step in problem solving. Adopting new procedures and sustaining the commitment to identify and signal problems was a last and critical step toward realizing improvement, requiring a manager to function as "teacher/coach" rather than "fixer/firefighter".

  11. TREATMENT OF METAL-LADEN HAZARDOUS WASTES WITH ADVANCED CLEAN COAL TECHNOLOGY BY-PRODUCTS

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    James T. Cobb, Jr.

    2003-09-12

    Metal-laden wastes can be stabilized and solidified using advanced clean coal technology by-products (CCTBs)--fluid bed combustor ash and spray drier solids. These utility-generated treatment chemicals are available for purchase through brokers, and commercial applications of this process are being practiced by treaters of metal-laden hazardous waste. A complex of regulations governs this industry, and sensitivities to this complex has discouraged public documentation of treatment of metal-laden hazardous wastes with CCTBs. This report provides a comprehensive public documentation of laboratory studies that show the efficacy of the stabilization and solidification of metal-laden hazardous wastes--such as lead-contaminated soils and sandblast residues--through treatmentmore » with CCTBs. It then describes the extensive efforts that were made to obtain the permits allowing a commercial hazardous waste treater to utilize CCTBs as treatment chemicals and to install the equipment required to do so. It concludes with the effect of this lengthy process on the ability of the treatment company to realize the practical, physical outcome of this effort, leading to premature termination of the project.« less

  12. Technology transfer through a network of standard methods and recommended practices - The case of petrochemicals

    NASA Astrophysics Data System (ADS)

    Batzias, Dimitris F.; Karvounis, Sotirios

    2012-12-01

    Technology transfer may take place in parallel with cooperative action between companies participating in the same organizational scheme or using one another as subcontractor (outsourcing). In this case, cooperation should be realized by means of Standard Methods and Recommended Practices (SRPs) to achieve (i) quality of intermediate/final products according to specifications and (ii) industrial process control as required to guarantee such quality with minimum deviation (corresponding to maximum reliability) from preset mean values of representative quality parameters. This work deals with the design of the network of SRPs needed in each case for successful cooperation, implying also the corresponding technology transfer, effectuated through a methodological framework developed in the form of an algorithmic procedure with 20 activity stages and 8 decision nodes. The functionality of this methodology is proved by presenting the path leading from (and relating) a standard test method for toluene, as petrochemical feedstock in the toluene diisocyanate production, to the (6 generations distance upstream) performance evaluation of industrial process control systems (ie., from ASTM D5606 to BS EN 61003-1:2004 in the SRPs network).

  13. Waterjet processes for coating removal

    NASA Technical Reports Server (NTRS)

    Burgess, Fletcher; Cosby, Steve; Hoppe, David

    1995-01-01

    USBI and NASA have been testing and investigating the use of high pressure water for coating removal for approximately the past 12 years at the Automated TPS (Thermal Protection System - ablative materials used for thermal protection during ascent and descent of the solid rocket boosters) Removal Facility located in the Productivity Enhancement Complex at Marshall Space Flight Center. Originally the task was to develop and automate the removal process and transfer the technology to a production facility at Kennedy Space Center. Since that time more and more applications and support roles for the waterjet technology have been realized. The facility has become a vital part of development activities ongoing at MSFC. It supports the development of environmentally compliant insulations, sealants, and coatings. It also supports bonding programs, test motors, and pressure vessels. The most recent role of the cell is supporting Thiokol Corporation's solid rocket motor program in the development of waterjet degreasing and paint stripping methods. Currently vapor degreasing methods use 500,000 lbs. of ozone depleting chemicals per year. This paper describes the major cell equipment, test methods practiced, and coatings that have been removed.

  14. Dairy Equipment Lubrication

    NASA Technical Reports Server (NTRS)

    1978-01-01

    Lake To Lake Dairy Cooperative, Manitowoc, Wisconsin, operates four plants in Wisconsin for processing milk, butter and cheese products from its 1,300 member farms. The large co-op was able to realize substantial savings by using NASA information for improved efficiency in plant maintenance. Under contract to Marshall Space Flight Center, Midwest Research Institute compiled a handbook consolidating information about commercially available lubricants. The handbook details chemical and physical properties, applications, specifications, test procedures and test data for liquid and solid lubricants. Lake To Lake's plant engineer used the handbook to effect savings in maintenance labor and materials costs by reducing the number of lubricants used on certain equipment. Strict U.S. Department of Agriculture and Food and Drug Administration regulations preclude lubrication changes n production equipment, but the co-op's maintenance chief was able to eliminate seven types of lubricants for ancillary equipment, such as compressors and high pressure pumps. Handbook data enabled him to select comparable but les expensive lubricants in the materials consolidation process, and simplified lubrication schedules and procedures. The handbook is in continuing use as a reference source when a new item of equipment is purchased.

  15. [Quality process control system of Chinese medicine preparation based on "holistic view"].

    PubMed

    Wang, Ya-Qi; Jiao, Jiao-Jiao; Wu, Zhen-Feng; Zheng, Qin; Yang, Ming

    2018-01-01

    "High quality, safety and effectiveness" are the primary principles for the pharmaceutical research and development process in China. The quality of products relies not only on the inspection method, but also on the design and development, process control and standardized management. The quality depends on the process control level. In this paper, the history and current development of quality control of traditional Chinese medicine (TCM) preparations are reviewed systematically. Based on the development model of international drug quality control and the misunderstanding of quality control of TCM preparations, the reasons for impacting the homogeneity of TCM preparations are analyzed and summarized. According to TCM characteristics, efforts were made to control the diversity of TCM, make "unstable" TCM into "stable" Chinese patent medicines, put forward the concepts of "holistic view" and "QbD (quality by design)", so as to create the "holistic, modular, data, standardized" model as the core of TCM preparation quality process control model. Scientific studies shall conform to the actual production of TCM preparations, and be conducive to supporting advanced equipment and technology upgrade, thoroughly applying the scientific research achievements in Chinese patent medicines, and promoting the cluster application and transformation application of TCM pharmaceutical technology, so as to improve the quality and effectiveness of the TCM industry and realize the green development. Copyright© by the Chinese Pharmaceutical Association.

  16. Video Production in the English Language Arts Classroom.

    ERIC Educational Resources Information Center

    Lund, Donna Joan

    1998-01-01

    Argues that teaching video production techniques in high-school English classes achieves the goals of language arts proficiency, media literacy, and student self-realization. Discusses preproduction; information search; script and storyboard; writing activities; oral communication activities; teamwork; aesthetic judgment; media literacy; affective…

  17. Ipso Nitration. Regiospecific Nitration via Ipso Nitration Products.

    DTIC Science & Technology

    1985-05-20

    products of nitration of alkylbenzenes and alkylphenol derivatives. The general pattern envisioned is shown in Scheme 1. In order to realize this...we have also explored solid state nitration of various alkylphenols . This procedure involves adsorbing concentrated nitric acid on alumina, followed

  18. Silicon-based products and solutions

    NASA Astrophysics Data System (ADS)

    Painchaud, Y.; Poulin, M.; Pelletier, F.; Latrasse, C.; Gagné, J.-F.; Savard, S.; Robidoux, G.; Picard, M.-.; Paquet, S.; Davidson, C.-.; Pelletier, M.; Cyr, M.; Paquet, C.; Guy, M.; Morsy-Osman, M.; Chagnon, M.; Plant, D. V.

    2014-03-01

    TeraXion started silicon photonics activities aiming at developing building blocks for new products and customized solutions. Passive and active devices have been developed including MMI couplers, power splitters, Bragg grating filters, high responsivity photodetectors, high speed modulators and variable optical attenuators. Packaging solutions including fiber attachment and hybrid integration using flip-chip were also developed. More specifically, a compact packaged integrated coherent receiver has been realized. Good performances were obtained as demonstrated by our system tests results showing transmission up to 4800 km with BER below hard FEC threshold. The package size is small but still limited by the electrical interface. Migrating to more compact RF interface would allow realizing the full benefit of this technology.

  19. Quantum learning of classical stochastic processes: The completely positive realization problem

    NASA Astrophysics Data System (ADS)

    Monràs, Alex; Winter, Andreas

    2016-01-01

    Among several tasks in Machine Learning, a specially important one is the problem of inferring the latent variables of a system and their causal relations with the observed behavior. A paradigmatic instance of this is the task of inferring the hidden Markov model underlying a given stochastic process. This is known as the positive realization problem (PRP), [L. Benvenuti and L. Farina, IEEE Trans. Autom. Control 49(5), 651-664 (2004)] and constitutes a central problem in machine learning. The PRP and its solutions have far-reaching consequences in many areas of systems and control theory, and is nowadays an important piece in the broad field of positive systems theory. We consider the scenario where the latent variables are quantum (i.e., quantum states of a finite-dimensional system) and the system dynamics is constrained only by physical transformations on the quantum system. The observable dynamics is then described by a quantum instrument, and the task is to determine which quantum instrument — if any — yields the process at hand by iterative application. We take as a starting point the theory of quasi-realizations, whence a description of the dynamics of the process is given in terms of linear maps on state vectors and probabilities are given by linear functionals on the state vectors. This description, despite its remarkable resemblance with the hidden Markov model, or the iterated quantum instrument, is however devoid of any stochastic or quantum mechanical interpretation, as said maps fail to satisfy any positivity conditions. The completely positive realization problem then consists in determining whether an equivalent quantum mechanical description of the same process exists. We generalize some key results of stochastic realization theory, and show that the problem has deep connections with operator systems theory, giving possible insight to the lifting problem in quotient operator systems. Our results have potential applications in quantum machine learning, device-independent characterization and reverse-engineering of stochastic processes and quantum processors, and more generally, of dynamical processes with quantum memory [M. Guţă, Phys. Rev. A 83(6), 062324 (2011); M. Guţă and N. Yamamoto, e-print arXiv:1303.3771(2013)].

  20. Operational control of large-sized polymer composite units of U-profile circular beam type by X-ray method

    NASA Astrophysics Data System (ADS)

    Kavalerov, B. V.; Anoshkin, A. N.; Osokin, V. M.; Tretyakov, A. A.; Potrakhov, N. N.; Bessonov, V. B.; Obodovskiy, A. V.

    2018-02-01

    The advantages of using the method of microfocus radiography in the non-destructive testing of aviation products are considered in the paper, using the example of a circular beam of a U-shaped profile made of polymer composite materials. The basic types of characteristic defects of parts arising in such a type are described both in the process of their manufacture and in the process of their exploitation, namely interlayer delaminations, pores and folds. Peculiarities of obtaining pseudo-volumetric images, which allow to increase the informativity about the structure of the object of control, as well as to identify the arising heterogeneities are given. A model of a robotic system is described that makes it possible to realize a small or multi-angle survey scheme, and, in particular, to carry out tomographic studies.

  1. The Value of Metrics for Science Data Center Management

    NASA Astrophysics Data System (ADS)

    Moses, J.; Behnke, J.; Watts, T. H.; Lu, Y.

    2005-12-01

    The Earth Observing System Data and Information System (EOSDIS) has been collecting and analyzing records of science data archive, processing and product distribution for more than 10 years. The types of information collected and the analysis performed has matured and progressed to become an integral and necessary part of the system management and planning functions. Science data center managers are realizing the importance that metrics can play in influencing and validating their business model. New efforts focus on better understanding of users and their methods. Examples include tracking user web site interactions and conducting user surveys such as the government authorized American Customer Satisfaction Index survey. This paper discusses the metrics methodology, processes and applications that are growing in EOSDIS, the driving requirements and compelling events, and the future envisioned for metrics as an integral part of earth science data systems.

  2. The effects of catalysts on the conversion of organic matter and bio-fuel production in the microwave pyrolysis of sludge at different temperatures.

    PubMed

    Ma, Rui; Huang, Xiaofei; Zhou, Yang; Fang, Lin; Sun, Shichang; Zhang, Peixin; Zhang, Xianghua; Zhao, Xuxin

    2017-08-01

    Adding catalyst could improve the yields and qualities of bio-gas and bio-oil, and realize the oriented production. Results showed that the catalytic gas-production capacities of CaO were higher than those of Fe 2 O 3 , and the bio-gas yield at 800°C reached a maximum of 35.1%. Because the polar cracking active sites of CaO reduced the activation energy of the pyrolysis reaction and resulted in high catalytic cracking efficiencies. In addition, the quality of bio-oil produced by CaO was superior to that by Fe 2 O 3 , although the bio-oil yield of CaO was relatively weak. The light bio-fuel oriented catalytic pyrolysis could be realized when adding different catalysts. At 800°C, CaO was 45% higher than Fe 2 O 3 in aspect of H 2 production while Fe 2 O 3 was 103% higher than CaO in aspect of CH 4 production. Therefore, CaO was more suitable for H 2 production and Fe 2 O 3 was more suitable for CH 4 production. Copyright © 2017 Elsevier Ltd. All rights reserved.

  3. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Fabbri, Andrea; Bonifazi, Giuseppe; Serranti, Silvia, E-mail: silvia.serranti@uniroma1.it

    Highlights: • BioMethane Potential of grape marcs was investigated. • Grape marcs were characterized to realize a micro-scale energy recovery. • Comparative BMP batch-tests utilizing lab-scale reactors were performed. • Biogas valorization by grape marcs anaerobic digestion at small scale is evaluated. - Abstract: The BiochemicalMethanePotential (BMP) of winery organic waste, with reference to two Italian red and white grapes (i.e. Nero Buono and Greco) by-products was investigated. The study was carried out to verify the possibility to reduce the production impact in a green-waste-management-chain-perspective. The possibility to efficiently utilize wine-related-by-products for energy production at a micro-scale (i.e. small-medium scalemore » winery production plant) was also verified. Results showed as a good correlation can be established between the percentage of COD removal and the biogas production, as the winery can produce, from its waste methanization, about 7800 kW h year{sup −1} electrical and 8900 kW h year{sup −1} thermal. A critical evaluation was performed about the possibility to utilize the proposed approach to realize an optimal biomass waste management and an energetic valorization in a local-energy-production-perspective.« less

  4. Quantum Stabilizer Codes Can Realize Access Structures Impossible by Classical Secret Sharing

    NASA Astrophysics Data System (ADS)

    Matsumoto, Ryutaroh

    We show a simple example of a secret sharing scheme encoding classical secret to quantum shares that can realize an access structure impossible by classical information processing with limitation on the size of each share. The example is based on quantum stabilizer codes.

  5. Microbiological and engineering aspects of biohydrogen production.

    PubMed

    Hallenbeck, Patrick C; Ghosh, Dipankar; Skonieczny, Monika T; Yargeau, Viviane

    2009-03-01

    Dramatically rising oil prices and increasing awareness of the dire environmental consequences of fossil fuel use, including startling effects of climate change, are refocusing attention worldwide on the search for alternative fuels. Hydrogen is poised to become an important future energy carrier. Renewable hydrogen production is pivotal in making it a truly sustainable replacement for fossil fuels, and for realizing its full potential in reducing greenhouse gas emissions. One attractive option is to produce hydrogen through microbial fermentation. This process would use readily available wastes as well as presently unutilized bioresources, including enormous supplies of agricultural and forestry wastes. These potential energy sources are currently not well exploited, and in addition, pose environmental problems. However, fuels are relatively low value products, placing severe constraints on any production process. Therefore, means must be sought to maximize yields and rates of hydrogen production while at the same time minimizing energy and capital inputs to the bioprocess. Here we review the various attributes of the characterized hydrogen producing bacteria as well as the preparation and properties of mixed microflora that have been shown to convert various substrates to hydrogen. Factors affecting yields and rates are highlighted and some avenues for increasing these parameters are explored. On the engineering side, we review the potential waste pre-treatment technologies and discuss the relevant bioprocess parameters, possible reactor configurations, including emerging technologies, and how engineering design-directed research might provide insight into the exploitation of the significant energy potential of biomass resources.

  6. Patient Satisfaction and Productivity

    DTIC Science & Technology

    2008-05-14

    in patient satisfaction were realized when as a matter of policy every patient was encouraged to complete a customer satisfaction card at each...Productivity 1 Army-Baylor University Graduate Program in Health and Business Administration Patient Satisfaction and Productivity Graduate Management...of policy every patient was encouraged to complete a customer satisfaction card at each appointment. This was due to several factors, most

  7. Application of elements of microbiological risk assessment in the food industry via a tiered approach.

    PubMed

    van Gerwen, Suzanne J C; Gorris, Leon G M

    2004-09-01

    Food safety control is a matter for concern for all parts of the food supply chain, including governments that develop food safety policy, food industries that must control potential hazards, and consumers who need to keep to the intended use of the food. In the future, food safety policy may be set using the framework of risk analysis, part of which is the development of (inter)national microbiological risk assessment (MRA) studies. MRA studies increase our understanding of the impact of risk management interventions and of the relationships among subsequent parts of food supply chains with regard to the safety of the food when it reaches the consumer. Application of aspects of MRA in the development of new food concepts has potential benefits for the food industry. A tiered approach to applying MRA can best realize these benefits. The tiered MRA approach involves calculation of microbial fate for a product and process design on the basis of experimental data (e.g., monitoring data on prevalence) and predictive microbiological models. Calculations on new product formulations and novel processing technologies provide improved understanding of microbial fate beyond currently known boundaries, which enables identification of new opportunities in process design. The outcome of the tiered approach focuses on developing benchmarks of potential consumer exposure to hazards associated with new products by comparison with exposure associated with products that are already on the market and have a safe history of use. The tiered prototype is a tool to be used by experienced microbiologists as a basis for advice to product developers and can help to make safety assurance for new food concepts transparent to food inspection services.

  8. Realization of Ru-C Eutectic Point for Evaluation of W-Re and IrRh/Ir Thermocouples

    NASA Astrophysics Data System (ADS)

    Ogura, H.; Masuyama, S.; Izuchi, M.; Yamazawa, K.; Arai, M.

    2015-03-01

    Tungsten-rhenium (W-Re) thermocouples are widely used in industry for measurements at high temperatures, up to . Since the electromotive force (emf) of a W-Re thermocouple is known to change during exposure at high temperatures, evaluation of the emf stability is essential for measuring temperature precisely and for realizing precise temperature control used to ensure the quality of products subject to annealing processes. To evaluate precisely the thermoelectric stability around , two Ru-C cells (crucible and Ru-C eutectic alloy) were constructed in our laboratory. The key feature of the cells is that their dimensions are large to ensure there is sufficient immersion available to evaluate the homogeneity characteristics of the thermocouples. By using one of the Ru-C cells, the drift and inhomogeneity of Type C (tungsten-5 % rhenium vs tungsten-26 % rhenium) thermocouples during an exposure to high temperature around were evaluated. Furthermore, to explore possible applications of the eutectic point to other types of high-temperature thermocouples, the drift of an IrRh/Ir thermocouple (iridium-40 % rhodium vs iridium) was also evaluated using another Ru-C cell. The tests with W-Re and IrRh/Ir thermocouples demonstrate that the newly developed Ru-C cells can be used to successfully realize melting plateaux repeatedly. This enables the long-term drift measurements essential for the evaluation and improvement of high-temperature thermocouples. The results obtained in this study will also be useful for evaluating the uncertainty of thermocouple calibrations at around.

  9. Commercial development of microalgal biotechnology: from the test tube to the marketplace.

    PubMed

    Olaizola, Miguel

    2003-07-01

    While humans have taken limited advantage of natural populations of microalgae for centuries (Nostoc in Asia and Spirulina in Africa and North America for sustenance), it is only recently that we have come to realize the potential of microalgal biotechnology. Microalgal biotechnology has the potential to produce a vast array of products including foodstuffs, industrial chemicals, compounds with therapeutic applications and bioremediation solutions from a virtually untapped source. From an industrial (i.e. commercial) perspective, the goal of microalgal biotechnology is to make money by developing marketable products. For such a business to succeed the following steps must be taken: identify a desirable metabolite and a microalga that produces and accumulates the desired metabolite, establish a large-scale production process for the desired metabolite, and market the desired metabolite. So far, the commercial achievements of microalgal biotechnology have been modest. Microalgae that produce dozens of desirable metabolites have been identified. Aided by high throughput screening technology even more leads will become available. However, the successes in large-scale production and product marketing have been few. We will discuss those achievements and difficulties from the industrial point of view by considering examples from industry, specially our own experience at Mera Pharmaceuticals.

  10. Waste biorefineries - integrating anaerobic digestion and microalgae cultivation for bioenergy production.

    PubMed

    Chen, Yi-di; Ho, Shih-Hsin; Nagarajan, Dillirani; Ren, Nan-Qi; Chang, Jo-Shu

    2018-04-01

    Commercialization of microalgal cultivation has been well realized in recent decades with the use of effective strains that can yield the target products, but it is still challenged by the high costs arising from mass production, harvesting, and further processing. Recently, more interest has been directed towards the utilization of waste resources, such as sludge digestate, to enhance the economic feasibility and sustainability of microalgae production. Anaerobic digestion for waste disposal and phototrophic microalgal cultivation are well-characterized technologies in both fields. However, integration of anaerobic digestion and microalgal cultivation to achieve substantial economic and environmental benefits is extremely limited, and thus deserves more attention and research effort. In particular, combining these two makes possible an ideal 'waste biorefinery' model, as the C/N/P content in the anaerobic digestate can be used to produce microalgal biomass that serves as feedstock for biofuels, while biogas upgrading can simultaneously be performed by phototrophic CO 2 fixation during microalgal growth. This review is thus aimed at elucidating recent advances as well as challenges and future directions with regard to waste biorefineries associated with the integration of anaerobic waste treatment and microalgal cultivation for bioenergy production. Copyright © 2017 Elsevier Ltd. All rights reserved.

  11. Renormalizing Entanglement Distillation.

    PubMed

    Waeldchen, Stephan; Gertis, Janina; Campbell, Earl T; Eisert, Jens

    2016-01-15

    Entanglement distillation refers to the task of transforming a collection of weakly entangled pairs into fewer highly entangled ones. It is a core ingredient in quantum repeater protocols, which are needed to transmit entanglement over arbitrary distances in order to realize quantum key distribution schemes. Usually, it is assumed that the initial entangled pairs are identically and independently distributed and are uncorrelated with each other, an assumption that might not be reasonable at all in any entanglement generation process involving memory channels. Here, we introduce a framework that captures entanglement distillation in the presence of natural correlations arising from memory channels. Conceptually, we bring together ideas from condensed-matter physics-ideas from renormalization and matrix-product states and operators-with those of local entanglement manipulation, Markov chain mixing, and quantum error correction. We identify meaningful parameter regions for which we prove convergence to maximally entangled states, arising as the fixed points of a matrix-product operator renormalization flow.

  12. Renormalizing Entanglement Distillation

    NASA Astrophysics Data System (ADS)

    Waeldchen, Stephan; Gertis, Janina; Campbell, Earl T.; Eisert, Jens

    2016-01-01

    Entanglement distillation refers to the task of transforming a collection of weakly entangled pairs into fewer highly entangled ones. It is a core ingredient in quantum repeater protocols, which are needed to transmit entanglement over arbitrary distances in order to realize quantum key distribution schemes. Usually, it is assumed that the initial entangled pairs are identically and independently distributed and are uncorrelated with each other, an assumption that might not be reasonable at all in any entanglement generation process involving memory channels. Here, we introduce a framework that captures entanglement distillation in the presence of natural correlations arising from memory channels. Conceptually, we bring together ideas from condensed-matter physics—ideas from renormalization and matrix-product states and operators—with those of local entanglement manipulation, Markov chain mixing, and quantum error correction. We identify meaningful parameter regions for which we prove convergence to maximally entangled states, arising as the fixed points of a matrix-product operator renormalization flow.

  13. Improving efficiency, reducing infection, and enhancing experience.

    PubMed

    Massa, Judith

    For health professionals to make an informed choice and tailor each bed bath to the individual needs of the patient, they must firstly understand the different bed bath options available, their impact on skin integrity, and any associated risks they may pose to the patient in terms of cross-infection. Only with this knowledge can health professionals determine the appropriate form and frequency of the bed bath. Specialist wipes offer significant improvements in skin care and a reduced risk of cross-infection, compared with the traditional soap and water bed bath. Use of these wipes also improves the efficiency of the process, which links to the Productive Ward Initiative and results in clinical staff (i.e. nursing staff, healthcare assistants) having more time available to undertake additional patient care activities. This product focus highlights the benefits of moving to a wipe-based bed bath method, and the significant efficiency savings that can be realized as a result.

  14. A realizable explicit algebraic Reynolds stress model for compressible turbulent flow with significant mean dilatation

    NASA Astrophysics Data System (ADS)

    Grigoriev, I. A.; Wallin, S.; Brethouwer, G.; Johansson, A. V.

    2013-10-01

    The explicit algebraic Reynolds stress model of Wallin and Johansson [J. Fluid Mech. 403, 89 (2000)] is extended to compressible and variable-density turbulent flows. This is achieved by correctly taking into account the influence of the mean dilatation on the rapid pressure-strain correlation. The resulting model is formally identical to the original model in the limit of constant density. For two-dimensional mean flows the model is analyzed and the physical root of the resulting quartic equation is identified. Using a fixed-point analysis of homogeneously sheared and strained compressible flows, we show that the new model is realizable, unlike the previous model. Application of the model together with a K - ω model to quasi one-dimensional plane nozzle flow, transcending from subsonic to supersonic regime, also demonstrates realizability. Negative "dilatational" production of turbulence kinetic energy competes with positive "incompressible" production, eventually making the total production negative during the spatial evolution of the nozzle flow. Finally, an approach to include the baroclinic effect into the dissipation equation is proposed and an algebraic model for density-velocity correlations is outlined to estimate the corrections associated with density fluctuations. All in all, the new model can become a significant tool for CFD (computational fluid dynamics) of compressible flows.

  15. Radio Frequency Plasma Synthesis of Boron Nitride Nanotubes (BNNTs) for Structural Applications: Part I

    NASA Technical Reports Server (NTRS)

    Hales, Stephen J.; Alexa, Joel A.; Jensen, Brian J.; Thomsen, Donald L.

    2016-01-01

    It is evident that nanotubes, such as carbon, boron nitride and even silicon, offer great potential for many aerospace applications. The opportunity exists to harness the extremely high strength and stiffness exhibited by high-purity, low-defect nanotubes in structural materials. Even though the technology associated with carbon nanotube (CNT) development is mature, the mechanical property benefits have yet to be fully realized. Boron nitride nanotubes (BNNTs) offer similar structural benefits, but exhibit superior chemical and thermal stability. A broader range of potential structural applications results, particularly as reinforcing agents for metal- and ceramic- based composites. However, synthesis of BNNTs is more challenging than CNTs mainly because of the higher processing temperatures required, and mass production techniques have yet to emerge. A promising technique is radio frequency plasma spray (RFPS), which is an inductively coupled, very high temperature process. The lack of electrodes and the self- contained, inert gas environment lend themselves to an ultraclean product. It is the aim of this White Paper to survey the state of the art with regard to nano-material production by analyzing the pros and cons of existing methods. The intention is to combine the best concepts and apply the NASA Langley Research Center (LaRC) RFPS facility to reliably synthesize large quantities of consistent, high-purity BNNTs.

  16. Controlled and facile synthesis of a self-assembled enzyme-inorganic catalyst based on flexible metal-coated fiber for an excellent removal of synthetic pollutants from aqueous environment

    NASA Astrophysics Data System (ADS)

    Zhu, Yao; Rong, Jian; Zhang, Tao; Xu, Jicheng; Dai, Yuting; Qiu, Fengxian

    2018-04-01

    The development of green sustainable chemistry opens the door to the application of biocatalytic in numerous fields for the research in industry and academia. As a common biological catalyst, enzyme catalysis is ideally suited and widely applicable for various desired reaction. In this work, a hierarchical structure laccase-Cu3(PO4)2·3H2O nanoflower-coated silica fiber (La-CNSF) was successfully fabricated with hundreds of Cu3(PO4)2 nanosheets formed on the processed silica fibers as the petal and laccase as the enzyme catalyst. It included two processes: first, Cu nanoparticles were directly grown on silica fiber cloth as a precursor and three-dimensional (3D) Cu3(PO4)2·3H2O nanoflower was self-assembled on Cu-coated fibers by post-processing. Then, La-CNSF was successfully immobilized via a simple one-step immersion reaction in a laccase-phosphate buffer solution (PBS) solution. The product was characterized by FTIR, XRD, SEM and UV-visible spectroscopy. Congo red was realized using La-CNSF as a biocatalyst. Compared with pure laccase, La-CNSF sample exhibits an enhanced catalytic activity. The flower-like structure assembled on the fiber provided La-CNSF high storage stability and reusability in contrast with free laccase. The superior catalytic performance of La-CNSF supports a potential strategy for purification of water pollutants, and it favors the realization of the engineering of large scale applications of enzyme catalysis.

  17. Training mechanical engineering students to utilize biological inspiration during product development.

    PubMed

    Bruck, Hugh A; Gershon, Alan L; Golden, Ira; Gupta, Satyandra K; Gyger, Lawrence S; Magrab, Edward B; Spranklin, Brent W

    2007-12-01

    The use of bio-inspiration for the development of new products and devices requires new educational tools for students consisting of appropriate design and manufacturing technologies, as well as curriculum. At the University of Maryland, new educational tools have been developed that introduce bio-inspired product realization to undergraduate mechanical engineering students. These tools include the development of a bio-inspired design repository, a concurrent fabrication and assembly manufacturing technology, a series of undergraduate curriculum modules and a new senior elective in the bio-inspired robotics area. This paper first presents an overview of the two new design and manufacturing technologies that enable students to realize bio-inspired products, and describes how these technologies are integrated into the undergraduate educational experience. Then, the undergraduate curriculum modules are presented, which provide students with the fundamental design and manufacturing principles needed to support bio-inspired product and device development. Finally, an elective bio-inspired robotics project course is present, which provides undergraduates with the opportunity to demonstrate the application of the knowledge acquired through the curriculum modules in their senior year using the new design and manufacturing technologies.

  18. Innovating for cash.

    PubMed

    Andrew, James P; Sirkin, Harold L

    2003-09-01

    Despite companies' almost fanatical worship of innovation, most new products don't generate money. That's because executives don't realize that the approach they take to commercializing a new product is as important as the innovation itself. Different approaches can generate very different levels of profit. Companies tend to favor one of three different innovation approaches, each with its own investment profile, profitability pattern, risk profile, and skill requirements. Most organizations are instinctively integrators: They manage all the steps needed to take a product to market themselves. Organizations can also choose to be orchestrators: They focus on some parts of the commercialization process and depend on partners to manage the rest. And finally, companies can be licensers: They sell or license a new product or idea to another organization that handles the commercialization process. Different innovations require different approaches. Selecting the most suitable approach, the authors' research found, often yields two or three times the profits of the least optimal approach. Yet companies tend to rely only on the mode most familiar to them. Executives would do better to take several different factors into account before deciding which tack to take, including the industry they're trying to enter, the specific characteristics of the innovation, and the risks involved in taking the product to market. By doing so, companies can match the approach to the opportunity and reap the maximum profit. Choosing the wrong approach, like Polaroid did, for example, can lead to the failure of both the product and the company. Optimizing their approaches, as Whirlpool has done, helps ensure that companies' innovations make money.

  19. Applying systems engineering methodologies to the micro- and nanoscale realm

    NASA Astrophysics Data System (ADS)

    Garrison Darrin, M. Ann

    2012-06-01

    Micro scale and nano scale technology developments have the potential to revolutionize smart and small systems. The application of systems engineering methodologies that integrate standalone, small-scale technologies and interface them with macro technologies to build useful systems is critical to realizing the potential of these technologies. This paper covers the expanding knowledge base on systems engineering principles for micro and nano technology integration starting with a discussion of the drivers for applying a systems approach. Technology development on the micro and nano scale has transition from laboratory curiosity to the realization of products in the health, automotive, aerospace, communication, and numerous other arenas. This paper focuses on the maturity (or lack thereof) of the field of nanosystems which is emerging in a third generation having transitioned from completing active structures to creating systems. The emphasis of applying a systems approach focuses on successful technology development based on the lack of maturity of current nano scale systems. Therefore the discussion includes details relating to enabling roles such as product systems engineering and technology development. Classical roles such as acquisition systems engineering are not covered. The results are also targeted towards small-scale technology developers who need to take into account systems engineering processes such as requirements definition, verification, and validation interface management and risk management in the concept phase of technology development to maximize the likelihood of success, cost effective micro and nano technology to increase the capability of emerging deployed systems and long-term growth and profits.

  20. Large-aperture MOEMS Fabry-Perot interferometer for miniaturized spectral imagers

    NASA Astrophysics Data System (ADS)

    Rissanen, Anna; Langner, Andreas; Viherkanto, Kai; Mannila, Rami

    2015-02-01

    VTT's optical MEMS Fabry-Perot interferometers (FPIs) are tunable optical filters, which enable miniaturization of spectral imagers into small, mass producible hand-held sensors with versatile optical measurement capabilities. FPI technology has also created a basis for various hyperspectral imaging instruments, ranging from nanosatellites, environmental sensing and precision agriculture with UAVs to instruments for skin cancer detection. Until now, these application demonstrations have been mostly realized with piezo-actuated FPIs fabricated by non-monolithical assembly method, suitable for achieving very large optical apertures and with capacity to small-to-medium volumes; however large-volume production of MEMS manufacturing supports the potential for emerging spectral imaging applications also in large-volume applications, such as in consumer/mobile products. Previously reported optical apertures of MEMS FPIs in the visible range have been up to 2 mm in size; this paper presents the design, successful fabrication and characterization of MEMS FPIs for central wavelengths of λ = 500 nm and λ = 650 nm with optical apertures up to 4 mm in diameter. The mirror membranes of the FPI structures consist of ALD (atomic layer deposited) TiO2-Al2O3 λ/4- thin film Bragg reflectors, with the air gap formed by sacrificial polymer etching in O2 plasma. The entire fabrication process is conducted below 150 °C, which makes it possible to monolithically integrate the filter structures on other ICdevices such as detectors. The realized MEMS devices are aimed for nanosatellite space application as breadboard hyperspectral imager demonstrators.

  1. Edge electrospinning: a facile needle-less approach to realize scaled up production of quality nanofibers

    NASA Astrophysics Data System (ADS)

    Bochinski, J. R.; Curtis, C.; Roman, M. P.; Clarke, L. I.; Wang, Q.; Thoppey, N. M.; Gorga, R. E.

    2014-03-01

    Utilizing unconfined polymer fluids (e.g., from solution or melt), edge electrospinning provides a straightforward approach for scaled up production of high quality nanofibers through the formation of many parallel jets. From simple geometries (using solution contained within a sharp-edged bowl or on a flat plate), jets form and spontaneously re-arrange on the fluid surface near the edge. Using appropriate control of the electric field induced feed rate, comparable per jet fabrication as traditional single-needle electrospinning can be realized, resulting in nanofibers with similar diameters, diameter distribution, and collected mat porosity. The presence of multiple jets proportionally enhances the production rate of the system, with minimal experimental complexity and without the possibility of clogging. Extending this needle-less approach to commercial polyethylene polymers, micron scale fibers can be melt electrospun using a similar apparatus. Support from National Science Foundation (CMMI-0800237).

  2. A spatially and temporally explicit, individual-based, life-history and productivity modeling approach for aquatic species

    EPA Science Inventory

    Realized life history expression and productivity in aquatic species, and salmonid fishes in particular, is the result of multiple interacting factors including genetics, habitat, growth potential and condition, and the thermal regime individuals experience, both at critical stag...

  3. The productivity limit of manufacturing blood cell therapy in scalable stirred bioreactors

    PubMed Central

    Bayley, Rachel; Ahmed, Forhad; Glen, Katie; McCall, Mark; Stacey, Adrian

    2017-01-01

    Abstract Manufacture of red blood cells (RBCs) from progenitors has been proposed as a method to reduce reliance on donors. Such a process would need to be extremely efficient for economic viability given a relatively low value product and high (2 × 1012) cell dose. Therefore, the aim of these studies was to define the productivity of an industry standard stirred‐tank bioreactor and determine engineering limitations of commercial red blood cells production. Cord blood derived CD34+ cells were cultured under erythroid differentiation conditions in a stirred micro‐bioreactor (Ambr™). Enucleated cells of 80% purity could be created under optimal physical conditions: pH 7.5, 50% oxygen, without gas‐sparging (which damaged cells) and with mechanical agitation (which directly increased enucleation). O2 consumption was low (~5 × 10–8 μg/cell.h) theoretically enabling erythroblast densities in excess of 5 × 108/ml in commercial bioreactors and sub‐10 l/unit production volumes. The bioreactor process achieved a 24% and 42% reduction in media volume and culture time, respectively, relative to unoptimized flask processing. However, media exchange limited productivity to 1 unit of erythroblasts per 500 l of media. Systematic replacement of media constituents, as well as screening for inhibitory levels of ammonia, lactate and key cytokines did not identify a reason for this limitation. We conclude that the properties of erythroblasts are such that the conventional constraints on cell manufacturing efficiency, such as mass transfer and metabolic demand, should not prevent high intensity production; furthermore, this could be achieved in industry standard equipment. However, identification and removal of an inhibitory mediator is required to enable these economies to be realized. Copyright © 2016 The Authors Journal of Tissue Engineering and Regenerative Medicine Published by John Wiley & Sons Ltd. PMID:27696710

  4. Cancer: Mitochondrial Origins.

    PubMed

    Stefano, George B; Kream, Richard M

    2015-12-01

    The primacy of glucose derived from photosynthesis as an existential source of chemical energy across plant and animal phyla is universally accepted as a core principle in the biological sciences. In mammalian cells, initial processing of glucose to triose phosphate intermediates takes place within the cytosolic glycolytic pathway and terminates with temporal transport of reducing equivalents derived from pyruvate metabolism by membrane-associated respiratory complexes in the mitochondrial matrix. The intra-mitochondrial availability of molecular oxygen as the ultimate electron acceptor drives the evolutionary fashioned chemiosmotic production of ATP as a high-efficiency biological process. The mechanistic bases of carcinogenesis have demonstrated profound alteration of normative mitochondrial function, notably dysregulated respiratory processes. Accordingly, the classic Warburg effect functionally links aerobic glycolysis, aberrant production and release of lactate, and metabolic down-regulation of mitochondrial oxidative processes with the carcinogenetic phenotype. We surmise, however, that aerobic fermentation by cancer cells may also represent a developmental re-emergence of an evolutionarily conserved early phenotype, which was "sidelined" with the emergence of mitochondrial oxidative phosphorylation as a primary mechanism for ATP production in normal cells. Regardless of state-dependent physiological status in mixed populations of cancer cells, it has been established that mitochondria are functionally linked to the initiation of cancer and its progression. Biochemical, molecular, and physiological differences in cancer cell mitochondria, notably mtDNA heteroplasmy and allele-specific expression of selected nuclear genes, may represent major focal points for novel targeting and elimination of cancer cells in metastatic disease afflicting human populations. To date, and despite considerable research efforts, the practical realization of advanced mitochondrial targeted therapies has not been forthcoming.

  5. Compact hybrid optoelectrical unit for image processing and recognition

    NASA Astrophysics Data System (ADS)

    Cheng, Gang; Jin, Guofan; Wu, Minxian; Liu, Haisong; He, Qingsheng; Yuan, ShiFu

    1998-07-01

    In this paper a compact opto-electric unit (CHOEU) for digital image processing and recognition is proposed. The central part of CHOEU is an incoherent optical correlator, which is realized with a SHARP QA-1200 8.4 inch active matrix TFT liquid crystal display panel which is used as two real-time spatial light modulators for both the input image and reference template. CHOEU can do two main processing works. One is digital filtering; the other is object matching. Using CHOEU an edge-detection operator is realized to extract the edges from the input images. Then the reprocessed images are sent into the object recognition unit for identifying the important targets. A novel template- matching method is proposed for gray-tome image recognition. A positive and negative cycle-encoding method is introduced to realize the absolute difference measurement pixel- matching on a correlator structure simply. The system has god fault-tolerance ability for rotation distortion, Gaussian noise disturbance or information losing. The experiments are given at the end of this paper.

  6. Realizing high-rate sulfur reduction under sulfate-rich conditions in a biological sulfide production system to treat metal-laden wastewater deficient in organic matter.

    PubMed

    Sun, Rongrong; Zhang, Liang; Zhang, Zefeng; Chen, Guang-Hao; Jiang, Feng

    2017-12-22

    Biological sulfur reduction can theoretically produce sufficient sulfide to effectively remove and recover heavy metals in the treatment of organics-deficient sulfate-rich metal-laden wastewater such as acid mine drainage and metallurgic wastewater, using 75% less organics than biological sulfate reduction. However, it is still unknown whether sulfur reduction can indeed compete with sulfate reduction, particularly under high-strength sulfate conditions. The aim of this study was to investigate the long-term feasibility of biological sulfur reduction under high sulfate conditions in a lab-scale sulfur-reducing biological sulfide production (BSP) system with sublimed sulfur added. In the 169-day trial, an average sulfide production rate (SPR) as high as 47 ± 9 mg S/L-h was achieved in the absence of sulfate, and the average SPR under sulfate-rich conditions was similar (53 ± 10 mg S/L-h) when 1300 mg S/L sulfate were fed with the influent. Interestingly, sulfate was barely reduced even at such a high strength and contributed to only 1.5% of total sulfide production. Desulfomicrobium was identified as the predominant sulfidogenic bacterium in the bioreactor. Batch tests further revealed that this sulfidogenic bacteria used elemental sulfur as the electron acceptor instead of the highly bioavailable sulfate, during which polysulfide acted as an intermediate, leading to an even higher bioavailability of sulfur than sulfate. The pathway of sulfur to sulfide conversion via polysulfide in the presence of both sulfur and sulfate was discussed. Collectively, when conditions favor polysulfide formation, sulfur reduction can be a promising and attractive technology to realize a high-rate and low-cost BSP process for treating sulfate-rich metal-laden wastewater. Copyright © 2017 Elsevier Ltd. All rights reserved.

  7. Detection of microbial concentration in ice-cream using the impedance technique.

    PubMed

    Grossi, M; Lanzoni, M; Pompei, A; Lazzarini, R; Matteuzzi, D; Riccò, B

    2008-06-15

    The detection of microbial concentration, essential for safe and high quality food products, is traditionally made with the plate count technique, that is reliable, but also slow and not easily realized in the automatic form, as required for direct use in industrial machines. To this purpose, the method based on impedance measurements represents an attractive alternative since it can produce results in about 10h, instead of the 24-48h needed by standard plate counts and can be easily realized in automatic form. In this paper such a method has been experimentally studied in the case of ice-cream products. In particular, all main ice-cream compositions of real interest have been considered and no nutrient media has been used to dilute the samples. A measurement set-up has been realized using benchtop instruments for impedance measurements on samples whose bacteria concentration was independently measured by means of standard plate counts. The obtained results clearly indicate that impedance measurement represents a feasible and reliable technique to detect total microbial concentration in ice-cream, suitable to be implemented as an embedded system for industrial machines.

  8. Realization of a gain with electromagnetically induced transparency system using non-degenerate Zeeman sublevels in 87 Rb

    NASA Astrophysics Data System (ADS)

    Zhou, Minchuan; Zhou, Zifan; Shahriar, Selim M.

    2017-11-01

    Previously, we had proposed an optically-pumped five-level Gain EIT (GEIT) system, which has a transparency dip superimposed on a gain profile and exhibits a negative dispersion suitable for the white-light-cavity signal-recycling (WLC-SR) scheme of the interferometric gravitational wave detector (Zhou et al., 2015). Using this system as the negative dispersion medium (NDM) in the WLC-SR, we get an enhancement in the quantum noise (QN) limited sensitivity-bandwidth product by a factor of ∼ 18. Here, we show how to realize this GEIT system in a realistic platform, using non-degenerate Zeeman sublevels in cold Rb atoms, employing anomalous dispersion at 795 nm. Using the Caves model for a phase insensitive linear amplifier, we show that an enhancement of the sensitivity-bandwidth product by a factor of ∼ 17 is possible for potentially realizable experimental parameters. While the current LIGO apparatus uses light at 1064 nm, a future embodiment thereof may operate at a wavelength that is consistent with the wavelength considered here.

  9. [Fast Detection of Camellia Sinensis Growth Process and Tea Quality Informations with Spectral Technology: A Review].

    PubMed

    Peng, Ji-yu; Song, Xing-lin; Liu, Fei; Bao, Yi-dan; He, Yong

    2016-03-01

    The research achievements and trends of spectral technology in fast detection of Camellia sinensis growth process information and tea quality information were being reviewed. Spectral technology is a kind of fast, nondestructive, efficient detection technology, which mainly contains infrared spectroscopy, fluorescence spectroscopy, Raman spectroscopy and mass spectroscopy. The rapid detection of Camellia sinensis growth process information and tea quality is helpful to realize the informatization and automation of tea production and ensure the tea quality and safety. This paper provides a review on its applications containing the detection of tea (Camellia sinensis) growing status(nitrogen, chlorophyll, diseases and insect pest), the discrimination of tea varieties, the grade discrimination of tea, the detection of tea internal quality (catechins, total polyphenols, caffeine, amino acid, pesticide residual and so on), the quality evaluation of tea beverage and tea by-product, the machinery of tea quality determination and discrimination. This paper briefly introduces the trends of the technology of the determination of tea growth process information, sensor and industrial application. In conclusion, spectral technology showed high potential to detect Camellia sinensis growth process information, to predict tea internal quality and to classify tea varieties and grades. Suitable chemometrics and preprocessing methods is helpful to improve the performance of the model and get rid of redundancy, which provides the possibility to develop the portable machinery. Future work is to develop the portable machinery and on-line detection system is recommended to improve the further application. The application and research achievement of spectral technology concerning about tea were outlined in this paper for the first time, which contained Camellia sinensis growth, tea production, the quality and safety of tea and by-produce and so on, as well as some problems to be solved and its future applicability in modern tea industrial.

  10. Realization of the Einstein-Podolsky-Rosen paradox using momentum- and position-entangled photons from spontaneous parametric down conversion.

    PubMed

    Howell, John C; Bennink, Ryan S; Bentley, Sean J; Boyd, R W

    2004-05-28

    We report on a momentum-position realization of the EPR paradox using direct detection in the near and far fields of the photons emitted by collinear type-II phase-matched parametric down conversion. Using this approach we achieved a measured two-photon momentum-position variance product of 0.01 variant Planck's over 2pi (2), which dramatically violates the bounds for the EPR and separability criteria.

  11. NASA AETC Test Technology Subproject

    NASA Technical Reports Server (NTRS)

    Bell, James

    2017-01-01

    Funds directed to improve measurement capabilities (pressure, force, flow, and temperature), test techniques and processes, and develop technologies critical to meeting NASA research needs and applicable to a multitude of facilities. Primarily works by funding small ($40K - $400K) tasks which result in a demonstration or initial capability of a new technology in an AETC facility.TT research and development tasks are generally TRL 3-6; they should be things which work in small scale or lab environments but need further development for use in production facilities.TT differs from CA in its focus on smaller-scale tasks and on instrumentation. Technologies developed by TT may become CA projects in order be fully realized within a facility.

  12. A Review of Industrial Heat Exchange Optimization

    NASA Astrophysics Data System (ADS)

    Yao, Junjie

    2018-01-01

    Heat exchanger is an energy exchange equipment, it transfers the heat from a working medium to another working medium, which has been wildly used in petrochemical industry, HVAC refrigeration, aerospace and so many other fields. The optimal design and efficient operation of the heat exchanger and heat transfer network are of great significance to the process industry to realize energy conservation, production cost reduction and energy consumption reduction. In this paper, the optimization of heat exchanger, optimal algorithm and heat exchanger optimization with different objective functions are discussed. Then, optimization of the heat exchanger and the heat exchanger network considering different conditions are compared and analysed. Finally, all the problems discussed are summarized and foresights are proposed.

  13. [Specific features in realization of the principle of minimum energy dissipation during individual development].

    PubMed

    Zotin, A A

    2012-01-01

    Realization of the principle of minimum energy dissipation (Prigogine's theorem) during individual development has been analyzed. This analysis has suggested the following reformulation of this principle for living objects: when environmental conditions are constant, the living system evolves to a current steady state in such a way that the difference between entropy production and entropy flow (psi(u) function) is positive and constantly decreases near the steady state, approaching zero. In turn, the current steady state tends to a final steady state in such a way that the difference between the specific entropy productions in an organism and its environment tends to be minimal. In general, individual development completely agrees with the law of entropy increase (second law of thermodynamics).

  14. Steam gasification of a thermally pretreated high lignin corn stover simultaneous saccharification and fermentation digester residue

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Howe, Daniel T.; Taasevigen, Danny; Garcia-Perez, Manuel

    Efficient conversion of all components in lignocellulosic biomass is essential to realizing economic feasibility of biorefineries. However, when utilizing biochemical pathways, lignin cannot be fermented. Furthermore, the high lignin and high ash residue resulting from simultaneous saccharification and fermentation (SSF) reactors is difficult to thermochemically process due to feed line plugging and bed agglomeration. In this study a corn stover SSF digester residue was thermally pretreated at 300°C for 22.5 minutes (min) and then gasified in a bubbling fluidized bed gasifier to study the effect of thermal pretreatment on its processing behavior. Untreated, pelletized SSF residue was gasified at themore » same conditions to establish the baseline processing behavior. Results indicate that the thermal pretreatment process removes a substantial portion of the polar and non-polar extractives, with a resultant increase in the concentration of lignin, cellulose, and ash. Feed line plugging was not observed, although bed agglomeration was occurring at similar rates for both feedstocks, suggesting that overall ash content is the most important factor affecting bed agglomeration. Benzene, phenol, and polyaromatic hydrocarbons in the tar were present at higher concentrations in the treated material, with higher tar loading in the product gas. Total product gas generation is lower for the treated material, although the overall gas composition does not change.« less

  15. Recent progress in printed 2/3D electronic devices

    NASA Astrophysics Data System (ADS)

    Klug, Andreas; Patter, Paul; Popovic, Karl; Blümel, Alexander; Sax, Stefan; Lenz, Martin; Glushko, Oleksandr; Cordill, Megan J.; List-Kratochvil, Emil J. W.

    2015-09-01

    New, energy-saving, efficient and cost-effective processing technologies such as 2D and 3D inkjet printing (IJP) for the production and integration of intelligent components will be opening up very interesting possibilities for industrial applications of molecular materials in the near future. Beyond the use of home and office based printers, "inkjet printing technology" allows for the additive structured deposition of photonic and electronic materials on a wide variety of substrates such as textiles, plastics, wood, stone, tiles or cardboard. Great interest also exists in applying IJP in industrial manufacturing such as the manufacturing of PCBs, of solar cells, printed organic electronics and medical products. In all these cases inkjet printing is a flexible (digital), additive, selective and cost-efficient material deposition method. Due to these advantages, there is the prospect that currently used standard patterning processes can be replaced through this innovative material deposition technique. A main issue in this research area is the formulation of novel functional inks or the adaptation of commercially available inks for specific industrial applications and/or processes. In this contribution we report on the design, realization and characterization of novel active and passive inkjet printed electronic devices including circuitry and sensors based on metal nanoparticle ink formulations and the heterogeneous integration into 2/3D printed demonstrators. The main emphasis of this paper will be on how to convert scientific inkjet knowledge into industrially relevant processes and applications.

  16. Development of 3D woven cellular structures for adaptive composites based on thermoplastic hybrid yarns

    NASA Astrophysics Data System (ADS)

    Sennewald, C.; Vorhof, M.; Schegner, P.; Hoffmann, G.; Cherif, C.; Boblenz, J.; Sinapius, M.; Hühne, C.

    2018-05-01

    Flexible cellular 3D structures with structure-inherent compliance made of fiber-reinforced composites have repeatedly aroused the interest of international research groups. Such structures offer the possibility to meet the increasing demand for flexible and adaptive structures. The aim of this paper is the development of cellular 3D structures based on weaving technology. Considering the desired geometry of the 3D structure, algorithms are developed for the formation of geometry through tissue sub-areas. Subsequently, these sub-areas are unwound into the weaving level and appropriate weave patterns are developed. A particular challenge is the realization of compliant mechanisms in the woven fabric. This can be achieved either by combining different materials or, in particular, by implementing large stiffness gradients by means of varying the woven fabrics thickness, whereas differences in wall thickness have to be realized with a factor of 1:10. A manufacturing technology based on the weaving process is developed for the realization of the developed 3D cellular structures. To this end, solutions for the processing of hybrid thermoplastic materials (e.g. tapes), solutions for the integration of inlays in the weaving process (thickening of partial areas), and solutions for tissue retraction, as well as for the fabric pull-off (linear pull-off system) are being developed. In this way, woven cellular 3D structures with woven outer layers and woven joint areas (compliance) can be realized in a single process step and are subsequently characterized.

  17. Reading on the Internet: Realizing and Constructing Potential Texts

    ERIC Educational Resources Information Center

    Cho, Byeong-Young; Afflerbach, Peter

    2015-01-01

    Successful Internet reading requires making strategic decisions about what texts to read and a sequence for reading them, all in accordance with readers' goals. In this paper, we describe the process of realizing and constructing potential texts as an important and critical part of successful Internet reading and use verbal report data to…

  18. AGILE integration into APC for high mix logic fab

    NASA Astrophysics Data System (ADS)

    Gatefait, M.; Lam, A.; Le Gratiet, B.; Mikolajczak, M.; Morin, V.; Chojnowski, N.; Kocsis, Z.; Smith, I.; Decaunes, J.; Ostrovsky, A.; Monget, C.

    2015-09-01

    For C040 technology and below, photolithographic depth of focus control and dispersion improvement is essential to secure product functionality. Critical 193nm immersion layers present initial focus process windows close to machine control capability. For previous technologies, the standard scanner sensor (Level sensor - LS) was used to map wafer topology and expose the wafer at the right Focus. Such optical embedded metrology, based on light reflection, suffers from reading issues that cannot be neglected anymore. Metrology errors are correlated to inspected product area for which material types and densities change, and so optical properties are not constant. Various optical phenomena occur across the product field during wafer inspection and have an effect on the quality and position of the reflected light. This can result in incorrect heights being recorded and exposures possibly being done out of focus. Focus inaccuracy associated to aggressive process windows on critical layers will directly impact product realization and therefore functionality and yield. ASML has introduced an air gauge sensor to complement the optical level sensor and lead to optimal topology metrology. The use of this new sensor is managed by the AGILE (Air Gauge Improved process LEveling) application. This measurement with no optical dependency will correct for optical inaccuracy of level sensor, and so improve best focus dispersion across the product. Due to the fact that stack complexity is more and more important through process steps flow, optical perturbation of standard Level sensor metrology is increasing and is becoming maximum for metallization layers. For these reasons AGILE feature implementation was first considered for contact and all metal layers. Another key point is that standard metrology will be sensitive to layer and reticle/product density. The gain of Agile will be enhanced for multiple product contribution mask and for complex System on Chip. Into ST context (High mix logic Fab) in term of product and technology portfolio AGILE corrects for up to 120nm of product topography error on process layer with less than 50nm depth of focus Based on tool functionalities delivered by ASML and on high volume manufacturing requirement, AGILE integration is a real challenge. Regarding ST requirements "Automatic AGILE" functionality developed by ASML was not a turnkey solution and a dedicated functionality was needed. A "ST homemade AGILE integration" has been fully developed and implemented within ASML and ST constraints. This paper describes this integration in our Advanced Process Control platform (APC).

  19. Cell therapy-processing economics: small-scale microfactories as a stepping stone toward large-scale macrofactories.

    PubMed

    Harrison, Richard P; Medcalf, Nicholas; Rafiq, Qasim A

    2018-03-01

    Manufacturing methods for cell-based therapies differ markedly from those established for noncellular pharmaceuticals and biologics. Attempts to 'shoehorn' these into existing frameworks have yielded poor outcomes. Some excellent clinical results have been realized, yet emergence of a 'blockbuster' cell-based therapy has so far proved elusive.  The pressure to provide these innovative therapies, even at a smaller scale, remains. In this process, economics research paper, we utilize cell expansion research data combined with operational cost modeling in a case study to demonstrate the alternative ways in which a novel mesenchymal stem cell-based therapy could be provided at small scale. This research outlines the feasibility of cell microfactories but highlighted that there is a strong pressure to automate processes and split the quality control cost-burden over larger production batches. The study explores one potential paradigm of cell-based therapy provisioning as a potential exemplar on which to base manufacturing strategy.

  20. Spacesuit glove manufacturing enhancements through the use of advanced technologies

    NASA Astrophysics Data System (ADS)

    Cadogan, David; Bradley, David; Kosmo, Joseph

    The sucess of astronauts performing extravehicular activity (EVA) on orbit is highly dependent upon the performance of their spacesuit gloves.A study has recently been conducted to advance the development and manufacture of spacesuit gloves. The process replaces the manual techniques of spacesuit glove manufacture by utilizing emerging technologies such as laser scanning, Computer Aided Design (CAD), computer generated two-dimensional patterns from three-dimensionl surfaces, rapid prototyping technology, and laser cutting of materials, to manufacture the new gloves. Results of the program indicate that the baseline process will not increase the cost of the gloves as compared to the existing styles, and in production, may reduce the cost of the gloves. perhaps the most important outcome of the Laserscan process is that greater accuracy and design control can be realized. Greater accuracy was achieved in the baseline anthropometric measurement and CAD data measurement which subsequently improved the design feature. This effectively enhances glove performance through better fit and comfort.

  1. Solution processed flexible organic thin film back-gated transistors based on polyimide dielectric films

    NASA Astrophysics Data System (ADS)

    Park, Janghoon; Min, Yoonki; Lee, Dongjin

    2018-04-01

    An organic thin film back-gated transistor (OBGT) was fabricated and characterized. The gate electrode was printed on the back side of substrate, and the dielectric layer was omitted by substituting the dielectric layer with the polyimide (PI) film substrate. Roll-to-roll (R2R) gravure printing, doctor blading, and drop casting methods were used to fabricate the OBGT. The printed OBGT device shows better performance compared with an OTFT device based on dielectric layer of BaTiO3. Additionally, a calendering process enhanced the performance by a factor of 3 to 7 (mobility: 0.016 cm2/V.s, on/off ratio: 9.17×103). A bending test was conducted to confirm the flexibility and durability of the OBGT device. The results show the fabricated device endures 20000-cyclic motions. The realized OBGT device was successfully fabricated and working, which is meaningful for production engineering from the viewpoint of process development.

  2. Multiscale Interfacial Strategy to Engineer Mixed Metal-Oxide Anodes toward Enhanced Cycling Efficiency.

    PubMed

    Ma, Yue; Tai, Cheuk-Wai; Li, Shaowen; Edström, Kristina; Wei, Bingqing

    2018-06-13

    Interconnected macro/mesoporous structures of mixed metal oxide (MMO) are developed on nickel foam as freestanding anodes for Li-ion batteries. The sustainable production is realized via a wet chemical etching process with bio-friendly chemicals. By means of divalent iron doping during an in situ recrystallization process, the as-developed MMO anodes exhibit enhanced levels of cycling efficiency. Furthermore, this atomic-scale modification coherently synergizes with the encapsulation layer across a micrometer scale. During this step, we develop a quasi-gel-state tri-copolymer, i.e., F127-resorcinol-melamine, as the N-doped carbon source to regulate the interfacial chemistry of the MMO electrodes. Electrochemical tests of the modified Fe x Ni 1- x O@NC-NiF anode in both half-cell and full-cell configurations unravel the favorable suppression of the irreversible capacity loss and satisfactory cyclability at the high rates. This study highlights a proof-of-concept modification strategy across multiple scales to govern the interfacial chemical process of the electrodes toward better reversibility.

  3. High Quality 3D Photonics using Nano Imprint Lithography of Fast Sol-gel Materials.

    PubMed

    Bar-On, Ofer; Brenner, Philipp; Siegle, Tobias; Gvishi, Raz; Kalt, Heinz; Lemmer, Uli; Scheuer, Jacob

    2018-05-18

    A method for the realization of low-loss integrated optical components is proposed and demonstrated. This approach is simple, fast, inexpensive, scalable for mass production, and compatible with both 2D and 3D geometries. The process is based on a novel dual-step soft nano imprint lithography process for producing devices with smooth surfaces, combined with fast sol-gel technology providing highly transparent materials. As a concrete example, this approach is demonstrated on a micro ring resonator made by direct laser writing (DLW) to achieve a quality factor improvement from one hundred thousand to more than 3 million. To the best of our knowledge this also sets a Q-factor record for UV-curable integrated micro-ring resonators. The process supports the integration of many types of materials such as light-emitting, electro-optic, piezo-electric, and can be readily applied to a wide variety of devices such as waveguides, lenses, diffractive elements and more.

  4. Grounding Lines Detecting Using LANDSAT8 Oli and CRYOSAT-2 Data Fusion

    NASA Astrophysics Data System (ADS)

    Li, F.; Guo, Y.; Zhang, Y.; Zhang, S.

    2018-04-01

    The grounding zone is the region where ice transitions from grounded ice sheet to freely floating ice shelf, grounding lines are actually more of a zone, typically over several kilometers. The mass loss from Antarctica is strongly linked to changes in the ice shelves and their grounding lines, since the variation in the grounding line can result in very rapid changes in glacier and ice-shelf behavior. Based on remote sensing observations, five global Antarctic grounding line products have been released internationally, including MOA, ASAID, ICESat, MEaSUREs, and Synthesized grounding lines. However, the five products could not provide the annual grounding line products of the whole Antarctic, even some products have stopped updating, which limits the time series analysis of Antarctic material balance to a certain extent. Besides, the accurate of single remote-sensing data based grounding line products is far from satisficed. Therefore, we use algorithms to extract grounding lines with SAR and Cryosat-2 data respectively, and combine the results of two kinds of grounding lines to obtain new products, we obtain a mature grounding line extraction algorithm process, so that we can realize the extraction of grounding line of the Antarctic each year in the future. The comparison between fusion results and the MOA product results indicate that there is a maximum deviation of 188.67 meters between the MOA product and the fusion result.

  5. Real-time video compressing under DSP/BIOS

    NASA Astrophysics Data System (ADS)

    Chen, Qiu-ping; Li, Gui-ju

    2009-10-01

    This paper presents real-time MPEG-4 Simple Profile video compressing based on the DSP processor. The programming framework of video compressing is constructed using TMS320C6416 Microprocessor, TDS510 simulator and PC. It uses embedded real-time operating system DSP/BIOS and the API functions to build periodic function, tasks and interruptions etcs. Realize real-time video compressing. To the questions of data transferring among the system. Based on the architecture of the C64x DSP, utilized double buffer switched and EDMA data transfer controller to transit data from external memory to internal, and realize data transition and processing at the same time; the architecture level optimizations are used to improve software pipeline. The system used DSP/BIOS to realize multi-thread scheduling. The whole system realizes high speed transition of a great deal of data. Experimental results show the encoder can realize real-time encoding of 768*576, 25 frame/s video images.

  6. Realization of the Temperature Scale in the Range from 234.3 K (Hg Triple Point) to 1084.62°C (Cu Freezing Point) in Croatia

    NASA Astrophysics Data System (ADS)

    Zvizdic, Davor; Veliki, Tomislav; Grgec Bermanec, Lovorka

    2008-06-01

    This article describes the realization of the International Temperature Scale in the range from 234.3 K (mercury triple point) to 1084.62°C (copper freezing point) at the Laboratory for Process Measurement (LPM), Faculty of Mechanical Engineering and Naval Architecture (FSB), University of Zagreb. The system for the realization of the ITS-90 consists of the sealed fixed-point cells (mercury triple point, water triple point and gallium melting point) and the apparatus designed for the optimal realization of open fixed-point cells which include the gallium melting point, tin freezing point, zinc freezing point, aluminum freezing point, and copper freezing point. The maintenance of the open fixed-point cells is described, including the system for filling the cells with pure argon and for maintaining the pressure during the realization.

  7. Parallel processing of embossing dies with ultrafast lasers

    NASA Astrophysics Data System (ADS)

    Jarczynski, Manfred; Mitra, Thomas; Brüning, Stephan; Du, Keming; Jenke, Gerald

    2018-02-01

    Functionalization of surfaces equips products and components with new features like hydrophilic behavior, adjustable gloss level, light management properties, etc. Small feature sizes demand diffraction-limited spots and adapted fluence for different materials. Through the availability of high power fast repeating ultrashort pulsed lasers and efficient optical processing heads delivering diffraction-limited small spot size of around 10μm it is feasible to achieve fluences higher than an adequate patterning requires. Hence, parallel processing is becoming of interest to increase the throughput and allow mass production of micro machined surfaces. The first step on the roadmap of parallel processing for cylinder embossing dies was realized with an eight- spot processing head based on ns-fiber laser with passive optical beam splitting, individual spot switching by acousto optical modulation and an advanced imaging. Patterning of cylindrical embossing dies shows a high efficiency of nearby 80%, diffraction-limited and equally spaced spots with pitches down to 25μm achieved by a compression using cascaded prism arrays. Due to the nanoseconds laser pulses the ablation shows the typical surrounding material deposition of a hot process. In the next step the processing head was adapted to a picosecond-laser source and the 500W fiber laser was replaced by an ultrashort pulsed laser with 300W, 12ps and a repetition frequency of up to 6MHz. This paper presents details about the processing head design and the analysis of ablation rates and patterns on steel, copper and brass dies. Furthermore, it gives an outlook on scaling the parallel processing head from eight to 16 individually switched beamlets to increase processing throughput and optimized utilization of the available ultrashort pulsed laser energy.

  8. Rapid prototyping of reflectors for vehicle lighting using laser activated remote phosphor

    NASA Astrophysics Data System (ADS)

    Lachmayer, Roland; Kloppenburg, Gerolf; Wolf, Alexander

    2015-03-01

    Bright white light sources are of significant importance for automotive front lighting systems. Today's upper class vehicles mainly use HID or LED as light source. As a further step in this development laser diode based systems offer high luminance, efficiency and allow the realization of new styling concepts and new dynamic lighting functions. These white laser diode systems can either be realized by mixing different spectral sources or by combining diodes with specific phosphors. Based on the approach of generating light using a laser and remote phosphor, lighting modules are manufactured. Four blue laser diodes (450 nm) are used to activate a phosphor coating and thus to achieve white light. A segmented paraboloid reflector generates the desired light distribution for an additional car headlamp. We use high speed milling and selective laser melting to build the reflector system for this lighting module. We compare the spectral reflection grade of these materials. Furthermore the generated modules are analyzed regarding their efficiency and light distribution. The use of Rapid Prototyping technologies allows an early validation of the chosen concept and is supposed to reduce cost and time in the product development process significantly. Therefor we discuss costs and times of the applied manufacturing technologies.

  9. Activation and control of microlens liquid arrays on functionalized polar electric crystal substrates by electro-wetting effect and temperature

    NASA Astrophysics Data System (ADS)

    Ferraro, Pietro; Grilli, Simonetta; Miccio, Lisa; Vespini, Veronica; Finizio, Sergio DeNicola Andrea

    2008-11-01

    In recent years a variety of liquid bases optical elements have been conceived, designed and fabricated even for commercial products like digital cameras o cellular phone cameras. The impressive development of microfluidic systems in conjunction with optics has led to the creation of a completely new Science field of investigation named optofludics. Optofludics, among others topics, deals with investigation and methods for realizing liquid micro-lenses. A variety of liquid micro-lenses have been designed and realized by using different configurations. We demonstrate that a lensing effect can be obtained in an open microfluidic system by using a thin layer of liquid on a polar electric crystal such as Lithium Niobate (LiNbO3). Electrowetting patterning on LiNbO3 surface is obtained by pyroelectric effect consisting in a simple but reliable electrodes-less and circuit-less configuration. The electrodes are intrinsically embedded into the substrate. The material is functionalised by means of a micro-engineering electric filed poling process. Lens array with variable focus has been demonstrated with a large number of lens elements (10x10) on micrometric scale (aperture of single lens 100 microns).

  10. Rewritable Painting Realized from Ambient-Sensitive Fluorescence of ZnO Nanoparticles

    PubMed Central

    Liu, Kai-Kai; Shan, Chong-Xin; He, Gao-Hang; Wang, Ruo-Qiu; Dong, Lin; Shen, De-Zhen

    2017-01-01

    Paper, as one of the most important information carriers, has contributed to the development and transmission of human civilization greatly. Meanwhile, a serious problem of environmental sustainable development caused by the production and utilization of paper has been resulted to modern society. Therefore, a simple and green route is urgently demanded to realize rewritable painting on paper. Herein, a simple route to rewritable painting on copy paper has been demonstrated by using eco-friendly ZnO nanoparticles (NPs) as fluorescent ink, and vinegar and soda that are frequently used in kitchen as erasing and neutralizing agents. Words or patterns written using the ZnO NPs as ink can be erased by vinegar vapour within five seconds, and after a neutralizing process in the ambient of soda vapour, the paper can be used for writing again. It is worth noting that the resolution and precision of the patterns produced via the above route degrade little after ten rewriting cycles, and the quality of the patterns produced using the ZnO NPs as ink fades little after being storage for several months, which promises the versatile potential applications of the rewriting route proposed in this paper. PMID:28169344

  11. Design and Manufacturing of Desalination System Powered by Solar Energy Using CDI Technique

    NASA Astrophysics Data System (ADS)

    Rostami, Mohammad Sajjad; Khashehchi, Morteza; Pipelzadeh, Ehsan

    2017-11-01

    Capacitive deionization (CDI) is an emerging energy efficient, low pressure and low capital intensive desalination process where ions are separated by a pure electrostatic force imposed by a small bias potential as low as 1 V That funded by an external Renewable (Solar) power supply to materials with high specific surface area. The main objective of this configuration is to separate the cation and anions on oppositely charged electrodes. One of the key parameters for commercial realization of CDI is the salt adsorption capacity of the electrodes. State-of-the-art electrode materials are based on porous activated carbon particles or carbon aerogels. Various electrode materials have been developed in the past, which have suffered from instability and lack of performance. Preliminary experimental results using carbon black, graphite powder, graphene ∖ graphite ∖ PTFE (Active ∖ Conductive ∖ binder) show that the graphene reduced via urea method is a suitable method to develop CDI electrode materials. Although some progress has been made, production of efficient and stable carbon based electrode materials for large scale desalination has not been fully realized. A new desalination technique using capacitive deionization.

  12. Realization of the international human right to health in an economically integrated North America.

    PubMed

    Kinney, Eleanor D

    2009-01-01

    With the North American Free Trade Agreement (NAFTA), the health care sectors of the United States, Canada, and Mexico are becoming more economically integrated. NAFTA poses major challenges to the realization of the international human right. These include: (1) Cross Border Trade in Medical Products, (2) Cross Border Trade in Medical Services, and the attendant investment protections, (3) Portability and Comparability of Health Insurance Coverage, and (4) Protection of Public Health Insurance Programs. The United States, Mexico, and Canada all provide public health insurance programs either to the entire population as in Canada or to vulnerable groups as in the United States. In none of these countries have private, for-profit providers and insurers been able to provide universal and affordable health coverage and care in a truly free market. Private insurers and for-profit providers should not profit from the care of the healthy and wealthy in ways that compromise the public programs that serve the poor and seriously ill. Nor should they be allowed to use NAFTA processes to compromise public programs. Policy makers must consider implications of NAFTA and move toward assuring access to affordable health care for all people on the North American continent.

  13. Smart electronics and microengineering: the Australian focus

    NASA Astrophysics Data System (ADS)

    Hariz, Alex

    1998-04-01

    Integrated MEMS together with signal-conditioning electronics on the same chip appears to be the ultimate solution to realizing smart computer devices integratable into larger systems. This in principle will lead to systems with decentralized intelligence leading to applications in numerous fields. It is conceived that such devices would be the product of merging two mature technologies, that of microsensors and that of IC manufacture which is enjoying a well established success. Using common and suitable materials it is reasonable to expect a high degree of compatibility with little modification to standard processes. The various aspects of this co-integration will be analyzed and factors critical to the viability of the process, that go beyond mere technical feasibility will be highlighted. Australian research in this area is strong and continues to grow. We will pinpoint opportunities and constraints to the promising prospect of smart electronics and MEMS.

  14. Self-assembled single-crystal silicon circuits on plastic

    PubMed Central

    Stauth, Sean A.; Parviz, Babak A.

    2006-01-01

    We demonstrate the use of self-assembly for the integration of freestanding micrometer-scale components, including single-crystal, silicon field-effect transistors (FETs) and diffusion resistors, onto flexible plastic substrates. Preferential self-assembly of multiple microcomponent types onto a common platform is achieved through complementary shape recognition and aided by capillary, fluidic, and gravitational forces. We outline a microfabrication process that yields single-crystal, silicon FETs in a freestanding, powder-like collection for use with self-assembly. Demonstrations of self-assembled FETs on plastic include logic inverters and measured electron mobility of 592 cm2/V-s. Finally, we extend the self-assembly process to substrates each containing 10,000 binding sites and realize 97% self-assembly yield within 25 min for 100-μm-sized elements. High-yield self-assembly of micrometer-scale functional devices as outlined here provides a powerful approach for production of macroelectronic systems. PMID:16968780

  15. Quantum walks and wavepacket dynamics on a lattice with twisted photons.

    PubMed

    Cardano, Filippo; Massa, Francesco; Qassim, Hammam; Karimi, Ebrahim; Slussarenko, Sergei; Paparo, Domenico; de Lisio, Corrado; Sciarrino, Fabio; Santamato, Enrico; Boyd, Robert W; Marrucci, Lorenzo

    2015-03-01

    The "quantum walk" has emerged recently as a paradigmatic process for the dynamic simulation of complex quantum systems, entanglement production and quantum computation. Hitherto, photonic implementations of quantum walks have mainly been based on multipath interferometric schemes in real space. We report the experimental realization of a discrete quantum walk taking place in the orbital angular momentum space of light, both for a single photon and for two simultaneous photons. In contrast to previous implementations, the whole process develops in a single light beam, with no need of interferometers; it requires optical resources scaling linearly with the number of steps; and it allows flexible control of input and output superposition states. Exploiting the latter property, we explored the system band structure in momentum space and the associated spin-orbit topological features by simulating the quantum dynamics of Gaussian wavepackets. Our demonstration introduces a novel versatile photonic platform for quantum simulations.

  16. Additive manufacturing of materials: Opportunities and challenges

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Babu, Sudarsanam Suresh; Love, Lonnie J.; Dehoff, Ryan R.

    Additive manufacturing (also known as 3D printing) is considered a disruptive technology for producing components with topologically optimized complex geometries as well as functionalities that are not achievable by traditional methods. The realization of the full potential of 3D printing is stifled by a lack of computational design tools, generic material feedstocks, techniques for monitoring thermomechanical processes under in situ conditions, and especially methods for minimizing anisotropic static and dynamic properties brought about by microstructural heterogeneity. In this paper, we discuss the role of interdisciplinary research involving robotics and automation, process control, multiscale characterization of microstructure and properties, and high-performancemore » computational tools to address each of these challenges. In addition, emerging pathways to scale up additive manufacturing of structural materials to large sizes (>1 m) and higher productivities (5–20 kg/h) while maintaining mechanical performance and geometrical flexibility are also discussed.« less

  17. Additive manufacturing of materials: Opportunities and challenges

    DOE PAGES

    Babu, Sudarsanam Suresh; Love, Lonnie J.; Dehoff, Ryan R.; ...

    2015-11-01

    Additive manufacturing (also known as 3D printing) is considered a disruptive technology for producing components with topologically optimized complex geometries as well as functionalities that are not achievable by traditional methods. The realization of the full potential of 3D printing is stifled by a lack of computational design tools, generic material feedstocks, techniques for monitoring thermomechanical processes under in situ conditions, and especially methods for minimizing anisotropic static and dynamic properties brought about by microstructural heterogeneity. In this paper, we discuss the role of interdisciplinary research involving robotics and automation, process control, multiscale characterization of microstructure and properties, and high-performancemore » computational tools to address each of these challenges. In addition, emerging pathways to scale up additive manufacturing of structural materials to large sizes (>1 m) and higher productivities (5–20 kg/h) while maintaining mechanical performance and geometrical flexibility are also discussed.« less

  18. Quantum walks and wavepacket dynamics on a lattice with twisted photons

    PubMed Central

    Cardano, Filippo; Massa, Francesco; Qassim, Hammam; Karimi, Ebrahim; Slussarenko, Sergei; Paparo, Domenico; de Lisio, Corrado; Sciarrino, Fabio; Santamato, Enrico; Boyd, Robert W.; Marrucci, Lorenzo

    2015-01-01

    The “quantum walk” has emerged recently as a paradigmatic process for the dynamic simulation of complex quantum systems, entanglement production and quantum computation. Hitherto, photonic implementations of quantum walks have mainly been based on multipath interferometric schemes in real space. We report the experimental realization of a discrete quantum walk taking place in the orbital angular momentum space of light, both for a single photon and for two simultaneous photons. In contrast to previous implementations, the whole process develops in a single light beam, with no need of interferometers; it requires optical resources scaling linearly with the number of steps; and it allows flexible control of input and output superposition states. Exploiting the latter property, we explored the system band structure in momentum space and the associated spin-orbit topological features by simulating the quantum dynamics of Gaussian wavepackets. Our demonstration introduces a novel versatile photonic platform for quantum simulations. PMID:26601157

  19. Research on TRIZ and CAIs Application Problems for Technology Innovation

    NASA Astrophysics Data System (ADS)

    Li, Xiangdong; Li, Qinghai; Bai, Zhonghang; Geng, Lixiao

    In order to realize application of invent problem solve theory (TRIZ) and computer aided innovation software (CAIs) , need to solve some key problems, such as the mode choice of technology innovation, establishment of technology innovation organization network(TION), and achievement of innovative process based on TRIZ and CAIs, etc.. This paper shows that the demands for TRIZ and CAIs according to the characteristics and existing problem of the manufacturing enterprises. Have explained that the manufacturing enterprises need to set up an open TION of enterprise leading type, and achieve the longitudinal cooperation innovation with institution of higher learning. The process of technology innovation based on TRIZ and CAIs has been set up from researching and developing point of view. Application of TRIZ and CAIs in FY Company has been summarized. The application effect of TRIZ and CAIs has been explained using technology innovation of the close goggle valve product.

  20. Piezoresistive Sensor with High Elasticity Based on 3D Hybrid Network of Sponge@CNTs@Ag NPs.

    PubMed

    Zhang, Hui; Liu, Nishuang; Shi, Yuling; Liu, Weijie; Yue, Yang; Wang, Siliang; Ma, Yanan; Wen, Li; Li, Luying; Long, Fei; Zou, Zhengguang; Gao, Yihua

    2016-08-31

    Pressure sensors with high elasticity are in great demand for the realization of intelligent sensing, but there is a need to develope a simple, inexpensive, and scalable method for the manufacture of the sensors. Here, we reported an efficient, simple, facile, and repeatable "dipping and coating" process to manufacture a piezoresistive sensor with high elasticity, based on homogeneous 3D hybrid network of carbon nanotubes@silver nanoparticles (CNTs@Ag NPs) anchored on a skeleton sponge. Highly elastic, sensitive, and wearable sensors are obtained using the porous structure of sponge and the synergy effect of CNTs/Ag NPs. Our sensor was also tested for over 2000 compression-release cycles, exhibiting excellent elasticity and cycling stability. Sensors with high performance and a simple fabrication process are promising devices for commercial production in various electronic devices, for example, sport performance monitoring and man-machine interfaces.

  1. Environment-friendly drilling operation technology

    NASA Astrophysics Data System (ADS)

    Luo, Huaidong; Jing, Ning; Zhang, Yanna; Huang, Hongjun; Wei, Jun

    2017-01-01

    Under the circumstance that international safety and environmental standards being more and more stringent, drilling engineering is facing unprecedented challenges, the extensive traditional process flow is no longer accepted, the new safe and environment-friendly process is more suitable to the healthy development of the industry. In 2015, CNPCIC adopted environment-friendly drilling technology for the first time in the Chad region, ensured the safety of well control, at the same time increased the environmental protection measure, reduced the risk of environmental pollution what obtain the ratification from local government. This technology carries out recovery and disposal of crude oil, cuttings and mud without falling on the ground. The final products are used in road and well site construction, which realizes the reutilization of drilling waste, reduces the operating cost, and provides a strong technical support for cost-cutting and performance-increase of drilling engineering under low oil price.

  2. Combined Detoxification and In-situ Product Removal by a Single Resin During Lignocellulosic Butanol Production

    PubMed Central

    Gao, Kai; Rehmann, Lars

    2016-01-01

    Phragmites australis (an invasive plant in North America) was used as feedstock for ABE (acetone-butanol-ethanol) fermentation by Clostridium saccharobutylicum. Sulphuric acid pretreated phragmites hydrolysate (SAEH) without detoxification inhibited butanol production (0.73 g/L butanol from 30 g/L sugars). The treatment of SAEH with resin L-493 prior the fermentation resulted in no inhibitory effects and an ABE titer of 14.44 g/L, including 5.49 g/L butanol was obtained, corresponding to an ABE yield and productivity of 0.49 g/g and 0.60 g/L/h, respectively. Dual functionality of the resin was realized by also using it as an in-situ product removal agent. Integrating in-situ product removal allowed for the use of high substrate concentrations without the typical product inhibition. Resin-detoxified SAEH was supplemented with neat glucose and an effective ABE titer of 33 g/L (including 13.7 g/L acetone, 16.4 g/L butanol and 1.9 g/L ethanol) was achieved with resin-based in-situ product removal, corresponding to an ABE yield and productivity of 0.41 g/g and 0.69 g/L/h, respectively. Both detoxification of the substrate and the products was achieved by the same resin, which was added prior the fermentation. Integrating hydrolysate detoxification and in-situ butanol removal in a batch process through single resin can potentially simplify cellulosic butanol production. PMID:27459906

  3. Combined Detoxification and In-situ Product Removal by a Single Resin During Lignocellulosic Butanol Production

    NASA Astrophysics Data System (ADS)

    Gao, Kai; Rehmann, Lars

    2016-07-01

    Phragmites australis (an invasive plant in North America) was used as feedstock for ABE (acetone-butanol-ethanol) fermentation by Clostridium saccharobutylicum. Sulphuric acid pretreated phragmites hydrolysate (SAEH) without detoxification inhibited butanol production (0.73 g/L butanol from 30 g/L sugars). The treatment of SAEH with resin L-493 prior the fermentation resulted in no inhibitory effects and an ABE titer of 14.44 g/L, including 5.49 g/L butanol was obtained, corresponding to an ABE yield and productivity of 0.49 g/g and 0.60 g/L/h, respectively. Dual functionality of the resin was realized by also using it as an in-situ product removal agent. Integrating in-situ product removal allowed for the use of high substrate concentrations without the typical product inhibition. Resin-detoxified SAEH was supplemented with neat glucose and an effective ABE titer of 33 g/L (including 13.7 g/L acetone, 16.4 g/L butanol and 1.9 g/L ethanol) was achieved with resin-based in-situ product removal, corresponding to an ABE yield and productivity of 0.41 g/g and 0.69 g/L/h, respectively. Both detoxification of the substrate and the products was achieved by the same resin, which was added prior the fermentation. Integrating hydrolysate detoxification and in-situ butanol removal in a batch process through single resin can potentially simplify cellulosic butanol production.

  4. Exploitation of olive mill wastewater and liquid cow manure for biogas production

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Dareioti, Margarita A.; Dokianakis, Spyros N.; Stamatelatou, Katerina

    2010-10-15

    Co-digestion of organic waste streams is an innovative technology for the reduction of methane/greenhouse gas emissions. Different organic substrates are combined to generate a homogeneous mixture as input to the anaerobic reactor in order to increase process performance, realize a more efficient use of equipment and cost-sharing by processing multiple waste streams in a single facility. In this study, the potential of anaerobic digestion for the treatment of a mixture containing olive mill wastewater (OMW) and liquid cow manure (LCM) using a two-stage process has been evaluated by using two continuously stirred tank reactors (CSTRs) under mesophilic conditions (35 {supmore » o}C) in order to separately monitor and control the processes of acidogenesis and methanogenesis. The overall process was studied with a hydraulic retention time (HRT) of 19 days. The digester was continuously fed with an influent composed (v/v) of 20% OMW and 80% LCM. The average removal of dissolved and total COD was 63.2% and 50%, respectively. The volatile solids (VS) removal was 34.2% for the examined mixture of feedstocks operating the system at an overall OLR of 3.63 g CODL{sub reactor}{sup -1}d{sup -1}. Methane production rate at the steady state reached 0.91 L CH{sub 4}L{sub reactor}{sup -1}d{sup -1} or 250.9 L CH{sub 4} at standard temperature and pressure conditions (STP) per kg COD fed to the system.« less

  5. Human-technology Integration

    NASA Astrophysics Data System (ADS)

    Mullen, Katharine M.

    Human-technology integration is the replacement of human parts and extension of human capabilities with engineered devices and substrates. Its result is hybrid biological-artificial systems. We discuss here four categories of products furthering human-technology integration: wearable computers, pervasive computing environments, engineered tissues and organs, and prosthetics, and introduce examples of currently realized systems in each category. We then note that realization of a completely artificial sytem via the path of human-technology integration presents the prospect of empirical confirmation of an aware artificially embodied system.

  6. Quantum learning of classical stochastic processes: The completely positive realization problem

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Monràs, Alex; Centre for Quantum Technologies, National University of Singapore, 3 Science Drive 2, Singapore 117543; Winter, Andreas

    2016-01-15

    Among several tasks in Machine Learning, a specially important one is the problem of inferring the latent variables of a system and their causal relations with the observed behavior. A paradigmatic instance of this is the task of inferring the hidden Markov model underlying a given stochastic process. This is known as the positive realization problem (PRP), [L. Benvenuti and L. Farina, IEEE Trans. Autom. Control 49(5), 651–664 (2004)] and constitutes a central problem in machine learning. The PRP and its solutions have far-reaching consequences in many areas of systems and control theory, and is nowadays an important piece inmore » the broad field of positive systems theory. We consider the scenario where the latent variables are quantum (i.e., quantum states of a finite-dimensional system) and the system dynamics is constrained only by physical transformations on the quantum system. The observable dynamics is then described by a quantum instrument, and the task is to determine which quantum instrument — if any — yields the process at hand by iterative application. We take as a starting point the theory of quasi-realizations, whence a description of the dynamics of the process is given in terms of linear maps on state vectors and probabilities are given by linear functionals on the state vectors. This description, despite its remarkable resemblance with the hidden Markov model, or the iterated quantum instrument, is however devoid of any stochastic or quantum mechanical interpretation, as said maps fail to satisfy any positivity conditions. The completely positive realization problem then consists in determining whether an equivalent quantum mechanical description of the same process exists. We generalize some key results of stochastic realization theory, and show that the problem has deep connections with operator systems theory, giving possible insight to the lifting problem in quotient operator systems. Our results have potential applications in quantum machine learning, device-independent characterization and reverse-engineering of stochastic processes and quantum processors, and more generally, of dynamical processes with quantum memory [M. Guţă, Phys. Rev. A 83(6), 062324 (2011); M. Guţă and N. Yamamoto, e-print http://arxiv.org/abs/1303.3771 (2013)].« less

  7. Design and research on the platform of network manufacture product electronic trading

    NASA Astrophysics Data System (ADS)

    Zhou, Zude; Liu, Quan; Jiang, Xuemei

    2003-09-01

    With the rapid globalization of market and business, E-trading affects every manufacture enterprise. However, the security of network manufacturing products of transmission on Internet is very important. In this paper we discussed the protocol of fair exchange and platform for network manufacture products E-trading based on fair exchange protocol and digital watermarking techniques. The platform realized reliable and copyright protection.

  8. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sciarrino, Fabio; De Martini, Francesco

    In several quantum information (QI) phenomena of large technological importance the information is carried by the phase of the quantum superposition states, or qubits. The phase-covariant cloning machine (PQCM) addresses precisely the problem of optimally copying these qubits with the largest attainable 'fidelity'. We present a general scheme which realizes the 1{yields}3 phase covariant cloning process by a combination of three different QI processes: the universal cloning, the NOT gate, and the projection over the symmetric subspace of the output qubits. The experimental implementation of a PQCM for polarization encoded qubits, the first ever realized with photons, is reported.

  9. A PLM-based automated inspection planning system for coordinate measuring machine

    NASA Astrophysics Data System (ADS)

    Zhao, Haibin; Wang, Junying; Wang, Boxiong; Wang, Jianmei; Chen, Huacheng

    2006-11-01

    With rapid progress of Product Lifecycle Management (PLM) in manufacturing industry, automatic generation of inspection planning of product and the integration with other activities in product lifecycle play important roles in quality control. But the techniques for these purposes are laggard comparing with techniques of CAD/CAM. Therefore, an automatic inspection planning system for Coordinate Measuring Machine (CMM) was developed to improve the automatization of measuring based on the integration of inspection system in PLM. Feature information representation is achieved based on a PLM canter database; measuring strategy is optimized through the integration of multi-sensors; reasonable number and distribution of inspection points are calculated and designed with the guidance of statistic theory and a synthesis distribution algorithm; a collision avoidance method is proposed to generate non-collision inspection path with high efficiency. Information mapping is performed between Neutral Interchange Files (NIFs), such as STEP, DML, DMIS, XML, etc., to realize information integration with other activities in the product lifecycle like design, manufacturing and inspection execution, etc. Simulation was carried out to demonstrate the feasibility of the proposed system. As a result, the inspection process is becoming simpler and good result can be got based on the integration in PLM.

  10. Cyanobacteria: Photoautotrophic Microbial Factories for the Sustainable Synthesis of Industrial Products

    PubMed Central

    Lau, Nyok-Sean; Matsui, Minami; Abdullah, Amirul Al-Ashraf

    2015-01-01

    Cyanobacteria are widely distributed Gram-negative bacteria with a long evolutionary history and the only prokaryotes that perform plant-like oxygenic photosynthesis. Cyanobacteria possess several advantages as hosts for biotechnological applications, including simple growth requirements, ease of genetic manipulation, and attractive platforms for carbon neutral production process. The use of photosynthetic cyanobacteria to directly convert carbon dioxide to biofuels is an emerging area of interest. Equipped with the ability to degrade environmental pollutants and remove heavy metals, cyanobacteria are promising tools for bioremediation and wastewater treatment. Cyanobacteria are characterized by the ability to produce a spectrum of bioactive compounds with antibacterial, antifungal, antiviral, and antialgal properties that are of pharmaceutical and agricultural significance. Several strains of cyanobacteria are also sources of high-value chemicals, for example, pigments, vitamins, and enzymes. Recent advances in biotechnological approaches have facilitated researches directed towards maximizing the production of desired products in cyanobacteria and realizing the potential of these bacteria for various industrial applications. In this review, the potential of cyanobacteria as sources of energy, bioactive compounds, high-value chemicals, and tools for aquatic bioremediation and recent progress in engineering cyanobacteria for these bioindustrial applications are discussed. PMID:26199945

  11. Laser micromachining as a metallization tool for microfluidic polymer stacks

    NASA Astrophysics Data System (ADS)

    Brettschneider, T.; Dorrer, C.; Czurratis, D.; Zengerle, R.; Daub, M.

    2013-03-01

    A novel assembly approach for the integration of metal structures into polymeric microfluidic systems is described. The presented production process is completely based on a single solid-state laser source, which is used to incorporate metal foils into a polymeric multi-layer stack by laser bonding and ablation processes. Chemical reagents or glues are not required. The polymer stack contains a flexible membrane which can be used for realizing microfluidic valves and pumps. The metal-to-polymer bond was investigated for different metal foils and plasma treatments, yielding a maximum peel strength of Rps = 1.33 N mm-1. A minimum structure size of 10 µm was determined by 3D microscopy of the laser cut line. As an example application, two different metal foils were used in combination to micromachine a standardized type-T thermocouple on a polymer substrate. An additional laser process was developed which allows metal-to-metal welding in close vicinity to the polymer substrate. With this process step, the reliability of the electrical contact could be increased to survive at least 400 PCR temperature cycles at very low contact resistances.

  12. Multifunctional Organic-Semiconductor Interfacial Layers for Solution-Processed Oxide-Semiconductor Thin-Film Transistor.

    PubMed

    Kwon, Guhyun; Kim, Keetae; Choi, Byung Doo; Roh, Jeongkyun; Lee, Changhee; Noh, Yong-Young; Seo, SungYong; Kim, Myung-Gil; Kim, Choongik

    2017-06-01

    The stabilization and control of the electrical properties in solution-processed amorphous-oxide semiconductors (AOSs) is crucial for the realization of cost-effective, high-performance, large-area electronics. In particular, impurity diffusion, electrical instability, and the lack of a general substitutional doping strategy for the active layer hinder the industrial implementation of copper electrodes and the fine tuning of the electrical parameters of AOS-based thin-film transistors (TFTs). In this study, the authors employ a multifunctional organic-semiconductor (OSC) interlayer as a solution-processed thin-film passivation layer and a charge-transfer dopant. As an electrically active impurity blocking layer, the OSC interlayer enhances the electrical stability of AOS TFTs by suppressing the adsorption of environmental gas species and copper-ion diffusion. Moreover, charge transfer between the organic interlayer and the AOS allows the fine tuning of the electrical properties and the passivation of the electrical defects in the AOS TFTs. The development of a multifunctional solution-processed organic interlayer enables the production of low-cost, high-performance oxide semiconductor-based circuits. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  13. Cheminformatics Applications and Physicochemical Property ...

    EPA Pesticide Factsheets

    The registration of new chemicals under the Toxic Substances Control Act (TSCA) and new pesticides under the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) requires knowledge of the process science underlying the transport and transformation of organic chemicals in natural ecosystems. The purpose of this presentation is to demonstrate how cheminformatics, using chemical terms language in combination with the output of physicochemical property calculators, can be employed to encode this knowledge and make it available to the appropriate decision makers. The encoded process science is realized through the execution of reaction libraries in simulators such as EPA’s Chemical Transformation Simulator (CTS). In support of the CTS, reaction libraries have, or are currently being developed for a number of transformation processes including hydrolysis, abiotic reduction, photolysis and disinfection by-product formation. Examples of how the process science in the peer-reviewed literature is being encoded will be presented. The purpose of this presentation is to demonstrate how cheminformatics, using chemical terms language in combination with the output of physicochemical property calculators, can be employed to encode this knowledge and make it available to the appropriate decision makers.

  14. A History of the Chemical Innovations in Silver-Halide Materials for Color PhotographyIII. Dye Tranfer Process — Instant Color Photography

    NASA Astrophysics Data System (ADS)

    Oishi, Yasushi

    A historical review of the technological developments of instant color photographic process, is presented with emphasis on the innovation processes at the following main turning points: 1) the creation of instant photography by E. H. Land in 1948 (one step processing by transfer of image-forming materials), 2) the advent of instant color photography based on dye developer, by Polaroid Corp., in 1963 (departing from dye-forming development, forming a direct positive preformed-dye image with a negative emulsion, but constraining the sensitive-material designs), 3) the introduction of a color instant product containing redox dye releaser with improved auto-positive emulsion, by Eastman Kodak Co., in 1976 (producing much improved color image quality, freed from the design constraints), and 4) the realization of absolute one-step photography by the integral film- unit system, by Polaroid in 1972. And the patent litigation (1976-86) raised by Polaroid against Kodak allegedly infringing on the integral film-unit patents caused the vast impacts on the industry.

  15. Planning and leading of the technological processes by mechanical working with microsoft project

    NASA Astrophysics Data System (ADS)

    Nae, I.; Grigore, N.

    2016-08-01

    Nowadays, fabrication systems and methods are being modified; new processing technologies come up, flow sheets develop a minimum number of phases, the flexibility of the technologies grows up, new methods and instruments of monitoring and leading the processing operations also come up. The technological course (route, entry, scheme, guiding) referring to the series of the operation, putting and execution phases of a mark in order to obtain the final product from the blank is represented by a sequence of activities realized by a logic manner, on a well determined schedule, with a determined budget and resources. Also, a project can be defined as a series of specific activities, methodical structured which they aim to finish a specific objective, within a fixed schedule and budget. Within the homogeneity between the project and the technological course, this research is presenting the defining of the technological course of mechanical chip removing process using Microsoft Project. Under these circumstances, this research highlights the advantages of this method: the celerity using of other technological alternatives in order to pick the optimal process, the job scheduling being constrained by any kinds, the standardization of some processing technological operations.

  16. Towards increased waste loading in high level waste glasses: Developing a better understanding of crystallization behavior

    DOE PAGES

    Marra, James C.; Kim, Dong -Sang

    2014-12-18

    A number of waste components in US defense high level radioactive wastes (HLW) have proven challenging for current Joule heated ceramic melter (JCHM) operations and have limited the ability to increase waste loadings beyond already realized levels. Many of these ''troublesome'' waste species cause crystallization in the glass melt that can negatively impact product quality or have a deleterious effect on melter processing. Thus, recent efforts at US Department of Energy laboratories have focused on understanding crystallization behavior within HLW glass melts and investigating approaches to mitigate the impacts of crystallization so that increases in waste loading can be realized.more » Advanced glass formulations have been developed to highlight the unique benefits of next-generation melter technologies such as the Cold Crucible Induction Melter (CCIM). Crystal-tolerant HLW glasses have been investigated to allow sparingly soluble components such as chromium to crystallize in the melter but pass out of the melter before accumulating. The Hanford site AZ-101 tank waste composition represents a waste group that is waste loading limited primarily due to high concentrations of Fe 2O 3 (with higher Al 2O 3). Systematic glass formulation development utilizing slightly higher process temperatures and higher tolerance to spinel crystals demonstrated that an increase in waste loading of more than 20% could be achieved for this waste composition, and by extension higher loadings for wastes in the same group.« less

  17. Imaging-based logics for ornamental stone quality chart definition

    NASA Astrophysics Data System (ADS)

    Bonifazi, Giuseppe; Gargiulo, Aldo; Serranti, Silvia; Raspi, Costantino

    2007-02-01

    Ornamental stone products are commercially classified on the market according to several factors related both to intrinsic lythologic characteristics and to their visible pictorial attributes. Sometimes these latter aspects prevail in quality criteria definition and assessment. Pictorial attributes are in any case also influenced by the performed working actions and the utilized tools selected to realize the final stone manufactured product. Stone surface finishing is a critical task because it can contribute to enhance certain aesthetic features of the stone itself. The study was addressed to develop an innovative set of methodologies and techniques able to quantify the aesthetic quality level of stone products taking into account both the physical and the aesthetical characteristics of the stones. In particular, the degree of polishing of the stone surfaces and the presence of defects have been evaluated, applying digital image processing strategies. Morphological and color parameters have been extracted developing specific software architectures. Results showed as the proposed approaches allow to quantify the degree of polishing and to identify surface defects related to the intrinsic characteristics of the stone and/or the performed working actions.

  18. Structuring Formal Control Systems Specifications for Reuse: Surviving Hardware Changes

    NASA Technical Reports Server (NTRS)

    Thompson, Jeffrey M.; Heimdahl, Mats P. E.; Erickson, Debra M.

    2000-01-01

    Formal capture and analysis of the required behavior of control systems have many advantages. For instance, it encourages rigorous requirements analysis, the required behavior is unambiguously defined, and we can assure that various safety properties are satisfied. Formal modeling is, however, a costly and time consuming process and if one could reuse the formal models over a family of products, significant cost savings would be realized. In an ongoing project we are investigating how to structure state-based models to achieve a high level of reusability within product families. In this paper we discuss a high-level structure of requirements models that achieves reusability of the desired control behavior across varying hardware platforms in a product family. The structuring approach is demonstrated through a case study in the mobile robotics domain where the desired robot behavior is reused on two diverse platforms-one commercial mobile platform and one build in-house. We use our language RSML (-e) to capture the control behavior for reuse and our tool NIMBUS to demonstrate how the formal specification can be validated and used as a prototype on the two platforms.

  19. Enhancement of negative hydrogen ion production in an electron cyclotron resonance source

    NASA Astrophysics Data System (ADS)

    Dugar-Zhabon, V. D.; Murillo, M. T.; Karyaka, V. I.

    2013-07-01

    In this paper, we present a method for improving the negative hydrogen ion yield in the electron cyclotron resonance source with driven plasma rings where the negative ion production is realized in two stages. First, the hydrogen and deuterium molecules are excited in collisions with plasma electrons to high-laying Rydberg and high vibration levels in the plasma volume. The second stage leads to negative ion production through the process of repulsive attachment of low-energy electrons by the excited molecules. The low-energy electrons originate due to a bombardment of the plasma electrode surface by ions of a driven ring and the thermoelectrons produced by a rare earth ceramic electrode, which is appropriately installed in the source chamber. The experimental and calculation data on the negative hydrogen ion generation rate demonstrate that very low-energy thermoelectrons significantly enhance the negative-ion generation rate that occurs in the layer adjacent to the plasma electrode surface. It is found that heating of the tungsten filaments placed in the source chamber improves the discharge stability and extends the pressure operation range.

  20. Application of micro- and nanotechnologies for the fabrication of optical devices

    NASA Astrophysics Data System (ADS)

    Ehrfeld, Wolfgang; Bauer, Hans-Dieter

    1998-03-01

    The development of micro-opto-electro-mechanical systems (MOEMS) and devices no longer focuses on feasibility studies and expensive demonstrators. On the contrary, fabrication of micro-optical components is already feeding dynamic markets with a large variety of products that are more or less on the verge of inexpensive mass production. A major application area for MOEMS is, without any doubt, tele- and datacommunications, while miniature optical sensors (e.g. spectrometers and interferometers) have a growing part in many kinds of biotechnological, chemical and pharmaceutical applications. In this presentation numerous examples for optical microstructures are given that range from the field of low cost fiberoptic components to polymer waveguide elements, from fiber switches to mass-producible microlenses made of thermoplastics or glass, and from microstructured photonic bandgap materials to optical sensor tips for investigating nanostructures. It is emphasized that for realizing MOEMS very different materials have to be processed while the necessary hybrid integration demands for specific automated assembly methods. In particular, the examples given show now microtechnologies can be adapted and combined with each other to take into account the special requirements of the product.

  1. Conversion of stranded waste-stream carbon and nutrients into value-added products via metabolically coupled binary heterotroph-photoautotroph system

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bohutskyi, Pavlo; Kucek, Leo A.; Hill, Eric

    Metabolic flexibility and robustness of phototroph- heterotroph co-cultures provide a flexible binary engineering platform for a variety of biotechnological and environmental applications. Here, we metabolically coupled a heterotrophic bacterium Bacillus subtilis with astaxanthin producing alga Haematococcus pluvialis and successfully applied this binary co-culture for conversion of the starch-rich waste stream into valuable astaxanthin-rich biomass. Importantly, the implemented system required less mass transfer of CO2 and O2 due to in-situ exchange between heterotroph and phototroph, which can contribute to reduction in energy consumption for wastewater treatment. In addition, the maximum reduction in chemical oxygen demand, total nitrogen and phosphorus reached 65%,more » 55% and 30%, respectively. The preliminary economic analysis indicated that realization of produced biomass with 0.8% astaxanthin content may generate annual revenues of $3.2M (baseline scenario) from treatment of wastewater (1,090 m3/day) from a potato processing plant. Moreover, the revenues may be increased up to $18.2M for optimized scenario with astaxanthin content in algae of 2%. This work demonstrates a successful proof-of-principle for conversion of waste carbon and nutrients into targeted value-added products through metabolic connection of heterotrophic and phototrophic organisms. Utilization of heterotrophic-algal binary cultures opens new perspectives for designing highly-efficient production processes for feedstock biomass production as well as allows utilization of variety of organic agricultural, chemical, or municipal wastes.« less

  2. Aerospace Fuels From Nonpetroleum Raw Materials

    NASA Technical Reports Server (NTRS)

    Palaszewski, Bryan A.; Hepp, Aloysius F.; Kulis, Michael J.; Jaworske, Donald A.

    2013-01-01

    Recycling human metabolic and plastic wastes minimizes cost and increases efficiency by reducing the need to transport consumables and return trash, respectively, from orbit to support a space station crew. If the much larger costs of transporting consumables to the Moon and beyond are taken into account, developing waste recycling technologies becomes imperative and possibly mission enabling. Reduction of terrestrial waste streams while producing energy and/or valuable raw materials is an opportunity being realized by a new generation of visionary entrepreneurs; several relevant technologies are briefly compared, contrasted and assessed for space applications. A two-step approach to nonpetroleum raw materials utilization is presented; the first step involves production of supply or producer gas. This is akin to synthesis gas containing carbon oxides, hydrogen, and simple hydrocarbons. The second step involves production of fuel via the Sabatier process, a methanation reaction, or another gas-to-liquid technology, typically Fischer-Tropsch processing. Optimization to enhance the fraction of product stream relevant to transportation fuels via catalytic (process) development at NASA Glenn Research Center is described. Energy utilization is a concern for production of fuels whether for operation on the lunar or Martian surface, or beyond. The term green relates to not only mitigating excess carbon release but also to the efficiency of energy usage. For space, energy usage can be an essential concern. Another issue of great concern is minimizing impurities in the product stream(s), especially those that are potential health risks and/or could degrade operations through catalyst poisoning or equipment damage; technologies being developed to remove heteroatom impurities are discussed. Alternative technologies to utilize waste fluids, such as a propulsion option called the resistojet, are discussed. The resistojet is an electric propulsion technology with a powered thruster to vaporize and heat a propellant to high temperature, hot gases are subsequently passed through a converging-diverging nozzle expanding gases to supersonic velocities. A resistojet can accommodate many different fluids, including various reaction chamber (by-)products.

  3. Aerospace Fuels from Nonpetroleum Raw Materials

    NASA Technical Reports Server (NTRS)

    Palaszewski, B. A.; Hepp, A. F.; Kulis, M. J.; Jaworske, D. A.

    2013-01-01

    Recycling human metabolic and plastic wastes minimizes cost and increases efficiency by reducing the need to transport consumables and return trash, respectively, from orbit to support a space station crew. If the much larger costs of transporting consumables to the Moon and beyond are taken into account, developing waste recycling technologies becomes imperative and possibly mission enabling. Reduction of terrestrial waste streams while producing energy and/or valuable raw materials is an opportunity being realized by a new generation of visionary entrepreneurs; several relevant technologies are briefly compared, contrasted and assessed for space applications. A two-step approach to nonpetroleum raw materials utilization is presented; the first step involves production of supply or producer gas. This is akin to synthesis gas containing carbon oxides, hydrogen, and simple hydrocarbons. The second step involves production of fuel via the Sabatier process, a methanation reaction, or another gas-to-liquid technology, typically Fischer- Tropsch processing. Optimization to enhance the fraction of product stream relevant to transportation fuels via catalytic (process) development at NASA GRC is described. Energy utilization is a concern for production of fuels whether for operation on the lunar or Martian surface, or beyond. The term "green" relates to not only mitigating excess carbon release but also to the efficiency of energy usage. For space, energy usage can be an essential concern. Other issues of great concern include minimizing impurities in the product stream(s), especially those that are potential health risks and/or could de-grade operations through catalyst poisoning or equipment damage; technologies being developed to remove heteroatom impurities are discussed. Alternative technologies to utilize waste fluids, such as a propulsion option called the resistojet, are discussed. The resistojet is an electric propulsion technology with a powered thruster to vaporize and heat a propellant to high temperature, hot gases are subsequently passed through a converging-diverging nozzle expanding gases to supersonic velocities. A resistojet can accommodate many different fluids, including various reaction chamber (by-)products.

  4. Representing vision and blindness.

    PubMed

    Ray, Patrick L; Cox, Alexander P; Jensen, Mark; Allen, Travis; Duncan, William; Diehl, Alexander D

    2016-01-01

    There have been relatively few attempts to represent vision or blindness ontologically. This is unsurprising as the related phenomena of sight and blindness are difficult to represent ontologically for a variety of reasons. Blindness has escaped ontological capture at least in part because: blindness or the employment of the term 'blindness' seems to vary from context to context, blindness can present in a myriad of types and degrees, and there is no precedent for representing complex phenomena such as blindness. We explore current attempts to represent vision or blindness, and show how these attempts fail at representing subtypes of blindness (viz., color blindness, flash blindness, and inattentional blindness). We examine the results found through a review of current attempts and identify where they have failed. By analyzing our test cases of different types of blindness along with the strengths and weaknesses of previous attempts, we have identified the general features of blindness and vision. We propose an ontological solution to represent vision and blindness, which capitalizes on resources afforded to one who utilizes the Basic Formal Ontology as an upper-level ontology. The solution we propose here involves specifying the trigger conditions of a disposition as well as the processes that realize that disposition. Once these are specified we can characterize vision as a function that is realized by certain (in this case) biological processes under a range of triggering conditions. When the range of conditions under which the processes can be realized are reduced beyond a certain threshold, we are able to say that blindness is present. We characterize vision as a function that is realized as a seeing process and blindness as a reduction in the conditions under which the sight function is realized. This solution is desirable because it leverages current features of a major upper-level ontology, accurately captures the phenomenon of blindness, and can be implemented in many domain-specific ontologies.

  5. Realizing the American Dream: A Parent Education Program Designed to Increase Latino Family Engagement in Children's Education

    ERIC Educational Resources Information Center

    Walker, Joan M. T.

    2016-01-01

    Grounded in Hoover-Dempsey and Sandler's parent involvement process model, the Realizing the American Dream (RAD) parent education program targets Latino parents' involvement beliefs and knowledge to enhance their involvement behaviors. Comparison of more than 2,000 parents' self-reported beliefs, knowledge, and behavior before and after RAD…

  6. Planning and Realization of Complex Intentions in Traumatic Brain Injury and Normal Aging

    ERIC Educational Resources Information Center

    Kliegel, Matthias; Eschen, Anne; Thone-Otto, Angelika I. T.

    2004-01-01

    The realization of delayed intentions (i.e., prospective memory) is a highly complex process composed of four phases: intention formation, retention, re-instantiation, and execution. The aim of this study was to investigate if executive functioning impairments are related to problems in the formation, re-instantiation, and execution of a delayed…

  7. Analysis of material flow in a utillzation technology of low grade manganese ore and sulphur coal complementary

    NASA Astrophysics Data System (ADS)

    Wang, Bo-Zhi; Deng, Biao; Su, Shi-Jun; Ding, Sang-Lan; Sun, Wei-Yi

    2018-03-01

    Electrolytic manganese is conventionally produced through low-grade manganese ore leaching in SO2, with the combustion of high sulfur coal. Subsequently the coal ash and manganese slag, produced by the combustion of high sulfur coal and preparation of electrolytic manganese, can be used as raw ingredients for the preparation of sulphoaluminate cement. In order to realize the `coal-electricity-sulfur-manganese-building material' system of complementary resource utilization, the conditions of material inflow and outflow in each process were determined using material flow analysis. The material flow models in each unit and process can be obtained by analyzed of material flow for new technology, and the input-output model could be obtained. Through the model, it is possible to obtain the quantity of all the input and output material in the condition of limiting the quantity of a substance. Taking one ton electrolytic manganese as a basis, the quantity of other input material and cements can be determined with the input-output model. The whole system had thusly achieved a cleaner production level. Therefore, the input-output model can be used for guidance in practical production.

  8. Multi-objective Analysis for a Sequencing Planning of Mixed-model Assembly Line

    NASA Astrophysics Data System (ADS)

    Shimizu, Yoshiaki; Waki, Toshiya; Yoo, Jae Kyu

    Diversified customer demands are raising importance of just-in-time and agile manufacturing much more than before. Accordingly, introduction of mixed-model assembly lines becomes popular to realize the small-lot-multi-kinds production. Since it produces various kinds on the same assembly line, a rational management is of special importance. With this point of view, this study focuses on a sequencing problem of mixed-model assembly line including a paint line as its preceding process. By taking into account the paint line together, reducing work-in-process (WIP) inventory between these heterogeneous lines becomes a major concern of the sequencing problem besides improving production efficiency. Finally, we have formulated the sequencing problem as a bi-objective optimization problem to prevent various line stoppages, and to reduce the volume of WIP inventory simultaneously. Then we have proposed a practical method for the multi-objective analysis. For this purpose, we applied the weighting method to derive the Pareto front. Actually, the resulting problem is solved by a meta-heuristic method like SA (Simulated Annealing). Through numerical experiments, we verified the validity of the proposed approach, and discussed the significance of trade-off analysis between the conflicting objectives.

  9. Short-rotation plantations

    Treesearch

    Philip E. Pope; Jeffery O. Dawson

    1989-01-01

    Short-rotation plantations offer several advantages over longer, more traditional rotations. They enhance the natural productivity of better sites and of tree species with rapid juvenile growth. Returns on investment are realized in a shorter period and the risk of loss is reduced compared with long term investments. Production of wood and fiber can be maximized by...

  10. A Game-Based Approach to an Entire Physical Chemistry Course

    ERIC Educational Resources Information Center

    Daubenfeld, Thorsten; Zenker, Dietmar

    2015-01-01

    We designed, implemented, and evaluated a game-based learning approach to increase student motivation and achievement for an undergraduate physical chemistry course. By focusing only on the most important game aspects, the implementation was realized with a production ratio of 1:8 (study load in hours divided by production effort in hours).…

  11. Toward the realization of erbium-doped GaN bulk crystals as a gain medium for high energy lasers

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sun, Z. Y.; Li, J.; Zhao, W. P.

    Er-doped GaN (Er:GaN) is a promising candidate as a gain medium for solid-state high energy lasers (HELs) at the technologically important and eye-safe 1.54 μm wavelength window, as GaN has superior thermal properties over traditional laser gain materials such as Nd:YAG. However, the attainment of wafer-scale Er:GaN bulk or quasi-bulk crystals is a prerequisite to realize the full potential of Er:GaN as a gain medium for HELs. We report the realization of freestanding Er:GaN wafers of 2-in. in diameter with a thickness on the millimeter scale. These freestanding wafers were obtained via growth by hydride vapor phase epitaxy in conjunction withmore » a laser-lift-off process. An Er doping level of 1.4 × 10{sup 20} atoms/cm{sup 3} has been confirmed by secondary ion mass spectrometry measurements. The freestanding Er:GaN wafers exhibit strong photoluminescent emission at 1.54 μm with its emission intensity increasing dramatically with wafer thickness under 980 nm resonant excitation. A low thermal quenching of 10% was measured for the 1.54 μm emission intensity between 10 K and 300 K. This work represents a significant step in providing a practical approach for producing Er:GaN materials with sufficient thicknesses and dimensions to enable the design of gain media in various geometries, allowing for the production of HELs with improved lasing efficiency, atmosphere transmission, and eye-safety.« less

  12. Imagine Moving Off the Planet

    NASA Technical Reports Server (NTRS)

    Elfrey, Priscilla R.

    2006-01-01

    Moving off the planet will be a defining moment of this century as landing on the Moon was in the last. For that to happen for humans to go where humans cannot go-- simulation is the sole solution. NASA supports simulation for life-cycle activities: design, analysis, test, checkout, operations, review and training. We contemplate time spans of a century and more, teams dispersed to different planets and the need for systems that endure or adapt as missions, teams and technology change. Without imagination such goals are impossible. But with imagination we can go outside our present perception of reality to think about and take action on what has been, is and, especially, what might be. Consciously maturing an imagined, possibly workable, idea through framing it to optimization to design, and building the product provides us with a new approach to innovation and simulation fidelity. We address options, analyze, test and make improvements in how we think and work. Each step includes increasingly exact information about costs, schedule, who will be needed, where, when and how. NASA i integrating such thinking into its Exploration Product Realization Hierarchy for simulation and analysis, test and verification, and stimulus response goals. Technically NASA follows a timeline of studies, analysis, definition, design, development and operations with concurrent documentation. We have matched this Product Realization Hierarchy with a continuum from image to realization that incorporates commitment, current and needed research and communication to ensure superior and creative problem solving as well as advances in simulation. One result is a new approach to collaborative systems. Another is a distributed observer network prototyped using game engine technology bringing advanced 3-D simulation of a simulation to the desktop enabling people to develop shared consensus of its meaning. Much of the value of simulation comes from developing in people their ability to make good decisions and reflexes supporting impressive achievement. Synthesizing imagination systematically into our work - and thus our success - is a challenge. NASA engineers have inventive minds, and the task is determining how best to enable them to devise the simulation and other innovations that will make a story so clear and so intellectually sound that people can carry out the mission for 50-100 years. This demands skills and knowledge traditionally under-respected and under-represented in technology organizations. But we are beginning to see that the process encourages efficiency and enables us to attain more effective results. We have to elicit imaginative, intelligent and effective ways to make better use than ever of the minds we have and will have available. We have to accept the challenge to accomplish tasks among dispersed interdisciplinary teams who must overcome changing priorities and technology, time and distance in order to maximize interactivity and innovation as never before. Attention to the process of innovation is a practical means to increase the efficiency of our intelligence. We have an obligation to reexamine and improve the process by which we approach and exercise innovation as we accept the charge to move off the planet.

  13. Evaluation of Mobil OCTGAIN{trademark} technology for the manufacture of reformulated gasoline via LP modeling

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Poddar, S.K.; Chum, K.; Ragsdale, R.

    1995-09-01

    Sulfur and olefins content of gasoline come primarily from the cat-cracked blendstock. Therefore hydrotreating cat cracked naphtha is a straight forward approach to reduce sulfur and olefin contents of gasoline and thereby reduce auto exhaust emission. However, this approach reduces the Octane number of gasoline which requires addition of Octane enhancer like MTBE to meet the stringent requirement of 1990 Clean Air Act Amendments and to produce Reformulated Gasoline (RFG). The paper examines the economic incentives of an innovative process technology which was developed and commercialized by Mobil known as OCTGAIN. The process utilizes fixed bed low pressure hardware andmore » uses a Mobil proprietary catalyst system to produce catalytically cracked (CC) gasoline component with thorough desulfurization and olefin reduction and practically no loss in Octane number. The economic evaluation of the OCTGAIN technology was conducted with Bechtel`s proprietary linear programming software, Process Industry Modeling System by introducing an OCTGAIN process block to a typical PADD-3 refinery configuration for gasoline production and satisfying RFG specifications. The results of the evaluation which involved twenty case studies, show that within the limitations of the study scope, the introduction of OCTGAIN technology creates a definite economic incentive over conventional hydrofinishing of CC naphtha. The profitability of OCTGAIN technology is dependent on the aromatics component of the gasoline pool. The economic advantage of OCTGAIN technology is realized primarily by higher production of premium gasoline and the ability to process lower cost high sulfur crude. The process also allows a better utilization of the FCCU and hydrocracker, if the refinery operation permits.« less

  14. Application of ASP Technology to Realize the Online Administrative License of the earthquake in Hunan Province

    NASA Astrophysics Data System (ADS)

    Tang, Hongliang; Kang, Chengxu; Tian, Youping

    2018-01-01

    Realizing the online handling of administrative approval of earthquakes is an important measure to improve work efficiency and facilitate people’s convenience. Based on the analysis of the characteristics and processes of the administrative licensing in the earthquake industry, this paper proposes an online processing model based on ASP technology and an online processing system based on B/S architecture. This paper presents the design and implementation methods. The application of the system shows that the system is simple in design and full in function, and can be used on mobile platforms such as computers and mobile phones, and has good practicability and forward-lookingness.

  15. Realization of the FPGA-based reconfigurable computing environment by the example of morphological processing of a grayscale image

    NASA Astrophysics Data System (ADS)

    Shatravin, V.; Shashev, D. V.

    2018-05-01

    Currently, robots are increasingly being used in every industry. One of the most high-tech areas is creation of completely autonomous robotic devices including vehicles. The results of various global research prove the efficiency of vision systems in autonomous robotic devices. However, the use of these systems is limited because of the computational and energy resources available in the robot device. The paper describes the results of applying the original approach for image processing on reconfigurable computing environments by the example of morphological operations over grayscale images. This approach is prospective for realizing complex image processing algorithms and real-time image analysis in autonomous robotic devices.

  16. Experimental realization of quantum teleportation from a photon to the vibration modes of a millimeter-sized diamond

    NASA Astrophysics Data System (ADS)

    Huang, Yuanyuan; Hou, Panyu; Yuan, Xinxing; Chang, Xiuying; Zu, Chong; He, Li; Duan, Luming; CenterQuantum Information, IIIS, Tsinghua University, Beijing 100084, PR China Team; Department of Physics, University of Michigan, Ann Arbor, Michigan 48109, USA Team

    2016-05-01

    Quantum teleportation is of great importance to various quantum technologies, and has been realized between light beams, trapped atoms, superconducting qubits, and defect spins in solids. Here we report an experimental demonstration of quantum teleportation from light beams to vibrational states of a macroscopic diamond under ambient conditions. In our experiment, the ultrafast laser technology provides the key tool for fast processing and detection of quantum states within its short life time in macroscopic objects consisting of many strongly interacting atoms that are coupled to the environment, and finally we demonstrate an average teleportation fidelity (90 . 6 +/- 1 . 0) % , clearly exceeding the classical limit of 2/3. Quantum control of the optomechanical coupling may provide efficient ways for realization of transduction of quantum signals, processing of quantum information, and sensing of small mechanical vibrations. Center for Quantum Information, IIIS, Tsinghua University, Beijing 100084, PR China.

  17. Fiber-connected position localization sensor networks

    NASA Astrophysics Data System (ADS)

    Pan, Shilong; Zhu, Dan; Fu, Jianbin; Yao, Tingfeng

    2014-11-01

    Position localization has drawn great attention due to its wide applications in radars, sonars, electronic warfare, wireless communications and so on. Photonic approaches to realize position localization can achieve high-resolution, which also provides the possibility to move the signal processing from each sensor node to the central station, thanks to the low loss, immunity to electromagnetic interference (EMI) and broad bandwidth brought by the photonic technologies. In this paper, we present a review on the recent works of position localization based on photonic technologies. A fiber-connected ultra-wideband (UWB) sensor network using optical time-division multiplexing (OTDM) is proposed to realize high-resolution localization and moving the signal processing to the central station. A 3.9-cm high spatial resolution is achieved. A wavelength-division multiplexed (WDM) fiber-connected sensor network is also demonstrated to realize location which is independent of the received signal format.

  18. Low power sensor network for wireless condition monitoring

    NASA Astrophysics Data System (ADS)

    Richter, Ch.; Frankenstein, B.; Schubert, L.; Weihnacht, B.; Friedmann, H.; Ebert, C.

    2009-03-01

    For comprehensive fatigue tests and surveillance of large scale structures, a vibration monitoring system working in the Hz and sub Hz frequency range was realized and tested. The system is based on a wireless sensor network and focuses especially on the realization of a low power measurement, signal processing and communication. Regarding the development, we met the challenge of synchronizing the wireless connected sensor nodes with sufficient accuracy. The sensor nodes ware realized by compact, sensor near signal processing structures containing components for analog preprocessing of acoustic signals, their digitization, algorithms for data reduction and network communication. The core component is a digital micro controller which performs the basic algorithms necessary for the data acquisition synchronization and the filtering. As a first application, the system was installed in a rotor blade of a wind power turbine in order to monitor the Eigen modes over a longer period of time. Currently the sensor nodes are battery powered.

  19. Topological Magnon Modes in Patterned Ferrimagnetic Insulator Thin Films.

    PubMed

    Li, Yun-Mei; Xiao, Jiang; Chang, Kai

    2018-05-09

    Manipulation of magnons opens an attractive direction in the future energy-efficient information processing devices. Such quasi-particles can transfer and process information free from the troublesome Ohmic loss in conventional electronic devices. Here, we propose to realize topologically protected magnon modes using the interface between the patterned ferrimagnetic insulator thin films of different configurations without the Dzyaloshinskii-Moriya interaction. The interface thus behaves like a perfect waveguide to conduct the magnon modes lying in the band gap. These modes are immune to backscattering even in sharply bent tracks, robust against the disorders, and maintain a high degree of coherence during propagation. We design a magnonic Mach-Zehnder interferometer, which realizes a continuous change of magnon signal with varying external magnetic field or driving frequency. Our results pave a new way for realizing topologically protected magnon waveguide and finally achieving a scalable low-dissipation spintronic devices and even the magnonic integrated circuit.

  20. Practical Use of Operation Data in the Process Industry

    NASA Astrophysics Data System (ADS)

    Kano, Manabu

    This paper aims to reveal real problems in the process industry and introduce recent development to solve such problems from the viewpoint of effective use of operation data. Two topics are discussed: virtual sensor and process control. First, in order to clarify the present state and problems, a part of our recent questionnaire survey of process control is quoted. It is emphasized that maintenance is a key issue not only for soft-sensors but also for controllers. Then, new techniques are explained. The first one is correlation-based just-in-time modeling (CoJIT), which can realize higher prediction performance than conventional methods and simplify model maintenance. The second is extended fictitious reference iterative tuning (E-FRIT), which can realize data-driven PID control parameter tuning without process modeling. The great usefulness of these techniques are demonstrated through their industrial applications.

  1. Feynman-Kac formula for stochastic hybrid systems.

    PubMed

    Bressloff, Paul C

    2017-01-01

    We derive a Feynman-Kac formula for functionals of a stochastic hybrid system evolving according to a piecewise deterministic Markov process. We first derive a stochastic Liouville equation for the moment generator of the stochastic functional, given a particular realization of the underlying discrete Markov process; the latter generates transitions between different dynamical equations for the continuous process. We then analyze the stochastic Liouville equation using methods recently developed for diffusion processes in randomly switching environments. In particular, we obtain dynamical equations for the moment generating function, averaged with respect to realizations of the discrete Markov process. The resulting Feynman-Kac formula takes the form of a differential Chapman-Kolmogorov equation. We illustrate the theory by calculating the occupation time for a one-dimensional velocity jump process on the infinite or semi-infinite real line. Finally, we present an alternative derivation of the Feynman-Kac formula based on a recent path-integral formulation of stochastic hybrid systems.

  2. The impact of high-end climate change on agricultural welfare

    PubMed Central

    Stevanović, Miodrag; Popp, Alexander; Lotze-Campen, Hermann; Dietrich, Jan Philipp; Müller, Christoph; Bonsch, Markus; Schmitz, Christoph; Bodirsky, Benjamin Leon; Humpenöder, Florian; Weindl, Isabelle

    2016-01-01

    Climate change threatens agricultural productivity worldwide, resulting in higher food prices. Associated economic gains and losses differ not only by region but also between producers and consumers and are affected by market dynamics. On the basis of an impact modeling chain, starting with 19 different climate projections that drive plant biophysical process simulations and ending with agro-economic decisions, this analysis focuses on distributional effects of high-end climate change impacts across geographic regions and across economic agents. By estimating the changes in surpluses of consumers and producers, we find that climate change can have detrimental impacts on global agricultural welfare, especially after 2050, because losses in consumer surplus generally outweigh gains in producer surplus. Damage in agriculture may reach the annual loss of 0.3% of future total gross domestic product at the end of the century globally, assuming further opening of trade in agricultural products, which typically leads to interregional production shifts to higher latitudes. Those estimated global losses could increase substantially if international trade is more restricted. If beneficial effects of atmospheric carbon dioxide fertilization can be realized in agricultural production, much of the damage could be avoided. Although trade policy reforms toward further liberalization help alleviate climate change impacts, additional compensation mechanisms for associated environmental and development concerns have to be considered. PMID:27574700

  3. The impact of high-end climate change on agricultural welfare.

    PubMed

    Stevanović, Miodrag; Popp, Alexander; Lotze-Campen, Hermann; Dietrich, Jan Philipp; Müller, Christoph; Bonsch, Markus; Schmitz, Christoph; Bodirsky, Benjamin Leon; Humpenöder, Florian; Weindl, Isabelle

    2016-08-01

    Climate change threatens agricultural productivity worldwide, resulting in higher food prices. Associated economic gains and losses differ not only by region but also between producers and consumers and are affected by market dynamics. On the basis of an impact modeling chain, starting with 19 different climate projections that drive plant biophysical process simulations and ending with agro-economic decisions, this analysis focuses on distributional effects of high-end climate change impacts across geographic regions and across economic agents. By estimating the changes in surpluses of consumers and producers, we find that climate change can have detrimental impacts on global agricultural welfare, especially after 2050, because losses in consumer surplus generally outweigh gains in producer surplus. Damage in agriculture may reach the annual loss of 0.3% of future total gross domestic product at the end of the century globally, assuming further opening of trade in agricultural products, which typically leads to interregional production shifts to higher latitudes. Those estimated global losses could increase substantially if international trade is more restricted. If beneficial effects of atmospheric carbon dioxide fertilization can be realized in agricultural production, much of the damage could be avoided. Although trade policy reforms toward further liberalization help alleviate climate change impacts, additional compensation mechanisms for associated environmental and development concerns have to be considered.

  4. Explaining process orientation failure and success in health care--three case studies.

    PubMed

    Hellman, Stefan; Kastberg, Gustaf; Siverbo, Sven

    2015-01-01

    In order to improve cooperation and collaboration between units, clinics and departments, many health care organizations (HCOs) have introduced process orientation. Several studies indicate problems in realizing these ambitions. The purpose of this paper is to explain and understand the success and failure of process orientation in HCOs. The authors conducted three case studies and applied Actor-Network Theory as an analytic lens. The realization of process orientation is hindered by neglect or resistance from physicians, who find the process targets to be of low medical priority. However, the authors also see that medical priorities are no stable entities but are susceptible to negotiations. Over time, process organization, process mapping, process measurement activities and the acting of enroled actors may have impact on medical priorities. Contrary to previous research, the findings indicate that New Public Management may not be the main obstacle against processes, that accounting figures may not be hard to disregard and that the role of leadership is not paramount.

  5. Design of permanent magnet synchronous motor speed control system based on SVPWM

    NASA Astrophysics Data System (ADS)

    Wu, Haibo

    2017-04-01

    The control system is designed to realize TMS320F28335 based on the permanent magnet synchronous motor speed control system, and put it to quoting all electric of injection molding machine. The system of the control method used SVPWM, through the sampling motor current and rotating transformer position information, realize speed, current double closed loop control. Through the TMS320F28335 hardware floating-point processing core, realize the application for permanent magnet synchronous motor in the floating point arithmetic, to replace the past fixed-point algorithm, and improve the efficiency of the code.

  6. Optically Transparent Microwave Polarizer Based On Quasi-Metallic Graphene.

    PubMed

    Grande, Marco; Bianco, Giuseppe Valerio; Vincenti, Maria Antonietta; de Ceglia, Domenico; Capezzuto, Pio; Scalora, Michael; D'Orazio, Antonella; Bruno, Giovanni

    2015-11-25

    In this paper, we report on the engineering and the realization of optically transparent graphene-based microwave devices using Chemical Vapour Deposition (CVD) graphene whose sheet resistance may be tailored down to values below 30 Ω/sq. In particular, we show that the process was successfully used to realize and characterize a simple, optically transparent graphene-based wire-grid polarizer at microwave frequencies (X band). The availability of graphene operating in a quasi-metallic region may allow the integration of graphene layers in several microwave components, thus leading to the realization of fully transparent (and flexible) microwave devices.

  7. Optically Transparent Microwave Polarizer Based On Quasi-Metallic Graphene

    PubMed Central

    Grande, Marco; Bianco, Giuseppe Valerio; Vincenti, Maria Antonietta; de Ceglia, Domenico; Capezzuto, Pio; Scalora, Michael; D’Orazio, Antonella; Bruno, Giovanni

    2015-01-01

    In this paper, we report on the engineering and the realization of optically transparent graphene-based microwave devices using Chemical Vapour Deposition (CVD) graphene whose sheet resistance may be tailored down to values below 30 Ω/sq. In particular, we show that the process was successfully used to realize and characterize a simple, optically transparent graphene-based wire-grid polarizer at microwave frequencies (X band). The availability of graphene operating in a quasi-metallic region may allow the integration of graphene layers in several microwave components, thus leading to the realization of fully transparent (and flexible) microwave devices. PMID:26603112

  8. Low-loss slot waveguides with silicon (111) surfaces realized using anisotropic wet etching

    NASA Astrophysics Data System (ADS)

    Debnath, Kapil; Khokhar, Ali; Boden, Stuart; Arimoto, Hideo; Oo, Swe; Chong, Harold; Reed, Graham; Saito, Shinichi

    2016-11-01

    We demonstrate low-loss slot waveguides on silicon-on-insulator (SOI) platform. Waveguides oriented along the (11-2) direction on the Si (110) plane were first fabricated by a standard e-beam lithography and dry etching process. A TMAH based anisotropic wet etching technique was then used to remove any residual side wall roughness. Using this fabrication technique propagation loss as low as 3.7dB/cm was realized in silicon slot waveguide for wavelengths near 1550nm. We also realized low propagation loss of 1dB/cm for silicon strip waveguides.

  9. Exploiting Data Intensive Applications on High Performance Computers to Unlock Australia's Landsat Archive

    NASA Astrophysics Data System (ADS)

    Purss, Matthew; Lewis, Adam; Edberg, Roger; Ip, Alex; Sixsmith, Joshua; Frankish, Glenn; Chan, Tai; Evans, Ben; Hurst, Lachlan

    2013-04-01

    Australia's Earth Observation Program has downlinked and archived satellite data acquired under the NASA Landsat mission for the Australian Government since the establishment of the Australian Landsat Station in 1979. Geoscience Australia maintains this archive and produces image products to aid the delivery of government policy objectives. Due to the labor intensive nature of processing of this data there have been few national-scale datasets created to date. To compile any Earth Observation product the historical approach has been to select the required subset of data and process "scene by scene" on an as-needed basis. As data volumes have increased over time, and the demand for the processed data has also grown, it has become increasingly difficult to rapidly produce these products and achieve satisfactory policy outcomes using these historic processing methods. The result is that we have been "drowning in a sea of uncalibrated data" and scientists, policy makers and the public have not been able to realize the full potential of the Australian Landsat Archive and its value is therefore significantly diminished. To overcome this critical issue, the Australian Space Research Program has funded the "Unlocking the Landsat Archive" (ULA) Project from April 2011 to June 2013 to improve the access and utilization of Australia's archive of Landsat data. The ULA Project is a public-private consortium led by Lockheed Martin Australia (LMA) and involving Geoscience Australia (GA), the Victorian Partnership for Advanced Computing (VPAC), the National Computational Infrastructure (NCI) at the Australian National University (ANU) and the Cooperative Research Centre for Spatial Information (CRC-SI). The outputs from the ULA project will become a fundamental component of Australia's eResearch infrastructure, with the Australian Landsat Archive hosted on the NCI and made openly available under a creative commons license. NCI provides access to researchers through significant HPC supercomputers, cloud infrastructure and data resources along with a large catalogue of software tools that make it possible to fully explore the potential of this data. Under the ULA Project, Geoscience Australia has developed a data-intensive processing workflow on the NCI. This system has allowed us to successfully process 11 years of the Australian Landsat Archive (from 2000 to 2010 inclusive) to standardized well-calibrated and sensor independent data products at a rate that allows for both bulk data processing of the archive and near-realtime processing of newly acquired satellite data. These products are available as Optical Surface Reflectance 25m (OSR25) and other derived products, such as Fractional Cover.

  10. Bistable metamaterial for switching and cascading elastic vibrations

    PubMed Central

    Foehr, André; Daraio, Chiara

    2017-01-01

    The realization of acoustic devices analogous to electronic systems, like diodes, transistors, and logic elements, suggests the potential use of elastic vibrations (i.e., phonons) in information processing, for example, in advanced computational systems, smart actuators, and programmable materials. Previous experimental realizations of acoustic diodes and mechanical switches have used nonlinearities to break transmission symmetry. However, existing solutions require operation at different frequencies or involve signal conversion in the electronic or optical domains. Here, we show an experimental realization of a phononic transistor-like device using geometric nonlinearities to switch and amplify elastic vibrations, via magnetic coupling, operating at a single frequency. By cascading this device in a tunable mechanical circuit board, we realize the complete set of mechanical logic elements and interconnect selected ones to execute simple calculations. PMID:28416663

  11. Core/shell silicon/polyaniline particles via in-flight plasma-induced polymerization

    NASA Astrophysics Data System (ADS)

    Yasar-Inceoglu, Ozgul; Zhong, Lanlan; Mangolini, Lorenzo

    2015-08-01

    Although silicon nanoparticles have potential applications in many relevant fields, there is often the need for post-processing steps to tune the property of the nanomaterial and to optimize it for targeted applications. In particular surface modification is generally necessary to both tune dispersibility of the particles in desired solvents to achieve optimal coating conditions, and to interface the particles with other materials to realize functional heterostructures. In this contribution we discuss the realization of core/shell silicon/polymer nanoparticles realized using a plasma-initiated in-flight polymerization process. Silicon particles are produced in a non-thermal plasma reactor using silane as a precursor. After synthesis they are aerodynamically injected into a second plasma reactor into which aniline vapor is introduced. The second plasma initiates the polymerization reactor leading to the formation of a 3-4 nm thick polymer shell surrounding the silicon core. The role of processing conditions on the properties of the polymeric shell is discussed. Preliminary results on the testing of this material as an anode for lithium ion batteries are presented.

  12. 3D-glass molds for facile production of complex droplet microfluidic chips.

    PubMed

    Tovar, Miguel; Weber, Thomas; Hengoju, Sundar; Lovera, Andrea; Munser, Anne-Sophie; Shvydkiv, Oksana; Roth, Martin

    2018-03-01

    In order to leverage the immense potential of droplet microfluidics, it is necessary to simplify the process of chip design and fabrication. While polydimethylsiloxane (PDMS) replica molding has greatly revolutionized the chip-production process, its dependence on 2D-limited photolithography has restricted the design possibilities, as well as further dissemination of microfluidics to non-specialized labs. To break free from these restrictions while keeping fabrication straighforward, we introduce an approach to produce complex multi-height (3D) droplet microfluidic glass molds and subsequent chip production by PDMS replica molding. The glass molds are fabricated with sub-micrometric resolution using femtosecond laser machining technology, which allows directly realizing designs with multiple levels or even continuously changing heights. The presented technique significantly expands the experimental capabilities of the droplet microfluidic chip. It allows direct fabrication of multilevel structures such as droplet traps for prolonged observation and optical fiber integration for fluorescence detection. Furthermore, the fabrication of novel structures based on sloped channels (ramps) enables improved droplet reinjection and picoinjection or even a multi-parallelized drop generator based on gradients of confinement. The fabrication of these and other 3D-features is currently only available at such resolution by the presented strategy. Together with the simplicity of PDMS replica molding, this provides an accessible solution for both specialized and non-specialized labs to customize microfluidic experimentation and expand their possibilities.

  13. Advanced Industrial Materials (AIM) Program annual progress report, FY 1997

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    1998-05-01

    The Advanced Industrial Materials (AIM) Program is a part of the Office of Industrial Technologies (OIT), Energy Efficiency and Renewable Energy, US Department of Energy (DOE). The mission of AIM is to support development and commercialization of new or improved materials to improve energy efficiency, productivity, product quality, and reduced waste in the major process industries. OIT has embarked on a fundamentally new way of working with industries--the Industries of the Future (IOF) strategy--concentrating on the major process industries that consume about 90% of the energy and generate about 90% of the waste in the industrial sector. These are themore » aluminum, chemical, forest products, glass, metalcasting, and steel industries. OIT has encouraged and assisted these industries in developing visions of what they will be like 20 or 30 years into the future, defining the drivers, technology needs, and barriers to realization of their visions. These visions provide a framework for development of technology roadmaps and implementation plans, some of which have been completed. The AIM Program supports IOF by conducting research and development on materials to solve problems identified in the roadmaps. This is done by National Laboratory/industry/university teams with the facilities and expertise needed to develop new and improved materials. Each project in the AIM Program has active industrial participation and support.« less

  14. Systems Engineering and Management Applications of ISO 9001:2015 for Government

    NASA Technical Reports Server (NTRS)

    Shepherd, Christena C.

    2016-01-01

    The manufacturing segment of the business world is busy assessing the impact of ISO 9001:2015, and updating their management systems to meet the required compliance date. What does the new revision mean for government agencies that deliver large engineering projects rather than mass production? In fact, the standard, especially the new revision, can be used quite readily for government agencies, or applied to specific projects, once it is understood in terms of the similarities with systems engineering and project management. From there it can be extrapolated to "mission realization" systems, and a Quality Management System (QMS) is a logical result that can bring order to processes and systems that likely already exist in some fashion. ISO 9001:2015 is less product-oriented than previous versions. It can be more broadly applied to public organizations as well as private; and to services (missions) as well as products. The emphasis on risk management in the revised standard provides the needed balance for weighing decisions with respect to cost, schedule, technical, safety, and regulatory compliance; so if this is not part of agency governance already, this is a good place to start, especially for large engineering projects. The Systems Engineering standard used for this analysis is from NASA's NPR 7123.1 NASA Systems Engineering Processes and Requirements; however, those who are more familiar with ISO/IEC 26702 Systems Engineering-application and management of the systems engineering process, or SAE/EIA 632 Processes for Engineering a System will also recognize the similarities. In reality, the QMS outlined by ISO 9001 reinforces the systems engineering processes, and serves to ensure that they are adequately implemented, although most of the ISO 9001 literature emphasizes the production and process aspects of the standard. Rather than beginning with ISO 9001and getting lost in the vocabulary, it is useful to begin with the systems engineering lifecycle. Identification of stakeholder expectations, identifying solutions, creating specific product or service designs, production of the product or service, delivery to the public, and the associated management, planning, and control processes, are a familiar place to begin thinking of the overall system of identifying, designing, and competing a project or mission. Lining up this lifecycle with the ISO requirements (see Figure 1) illustrates how a quality management system is concerned with the same processes, and provides a governance and assurance function. If implemented properly, there are cost savings resulting from less rework, repair, reprocessing, failures, misplaced documents, and similar types of deficiencies1. Starting with an organization's systems engineering processes allows the organization to use their own terminology for a QMS plan, and tailor the plan to their own project or organization, so that it is more easily developed, understood, and implemented.

  15. Conformation-based signal transfer and processing at the single-molecule level

    NASA Astrophysics Data System (ADS)

    Li, Chao; Wang, Zhongping; Lu, Yan; Liu, Xiaoqing; Wang, Li

    2017-11-01

    Building electronic components made of individual molecules is a promising strategy for the miniaturization and integration of electronic devices. However, the practical realization of molecular devices and circuits for signal transmission and processing at room temperature has proven challenging. Here, we present room-temperature intermolecular signal transfer and processing using SnCl2Pc molecules on a Cu(100) surface. The in-plane orientations of the molecules are effectively coupled via intermolecular interaction and serve as the information carrier. In the coupled molecular arrays, the signal can be transferred from one molecule to another in the in-plane direction along predesigned routes and processed to realize logical operations. These phenomena enable the use of molecules displaying intrinsic bistable states as complex molecular devices and circuits with novel functions.

  16. Enhancement of magnetoresistance by hydrogen ion treatment for current-perpendicular-to-plane giant magnetoresistive films with a current-confined-path nano-oxide layer

    NASA Astrophysics Data System (ADS)

    Yuasa, H.; Hara, M.; Murakami, S.; Fuji, Y.; Fukuzawa, H.; Zhang, K.; Li, M.; Schreck, E.; Wang, P.; Chen, M.

    2010-09-01

    We have enhanced magnetoresistance (MR) for current-perpendicular-to-plane giant-magnetoresistive (CPP-GMR) films with a current-confined-path nano-oxide layer (CCP-NOL). In order to realize higher purity in Cu for CCPs, hydrogen ion treatment (HIT) was applied as the CuOx reduction process. By applying the HIT process, an MR ratio was increased to 27.4% even in the case of using conventional FeCo magnetic layer, from 13.0% for a reference without the HIT process. Atom probe tomography data confirmed oxygen reduction by the HIT process in the CCP-NOL. The relationship between oxygen counts and MR ratio indicates that further oxygen reduction would realize an MR ratio greater than 50%.

  17. Improving patient care in cardiac surgery using Toyota production system based methodology.

    PubMed

    Culig, Michael H; Kunkle, Richard F; Frndak, Diane C; Grunden, Naida; Maher, Thomas D; Magovern, George J

    2011-02-01

    A new cardiac surgery program was developed in a community hospital setting using the operational excellence (OE) method, which is based on the principles of the Toyota production system. The initial results of the first 409 heart operations, performed over the 28 months between March 1, 2008, and June 30, 2010, are presented. Operational excellence methodology was taught to the cardiac surgery team. Coaching started 2 months before the opening of the program and continued for 24 months. Of the 409 cases presented, 253 were isolated coronary artery bypass graft operations. One operative death occurred. According to the database maintained by The Society of Thoracic Surgeons, the risk-adjusted operative mortality rate was 61% lower than the regional rate. Likewise, the risk-adjusted rate of major complications was 57% lower than The Society of Thoracic Surgeons regional rate. Daily solution to determine cause was attempted on 923 distinct perioperative problems by all team members. Using the cost of complications as described by Speir and coworkers, avoiding predicted complications resulted in a savings of at least $884,900 as compared with the regional average. By the systematic use of a real time, highly formatted problem-solving methodology, processes of care improved daily. Using carefully disciplined teamwork, reliable implementation of evidence-based protocols was realized by empowering the front line to make improvements. Low rates of complications were observed, and a cost savings of $3,497 per each case of isolated coronary artery bypass graft was realized. Copyright © 2011 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.

  18. Biofouling and biocorrosion in industrial water systems.

    PubMed

    Coetser, S E; Cloete, T E

    2005-01-01

    Corrosion associated with microorganisms has been recognized for over 50 years and yet the study of microbiologically influenced corrosion (MIC) is relatively new. MIC can occur in diverse environments and is not limited to aqueous corrosion under submerged conditions, but also takes place in humid atmospheres. Biofouling of industrial water systems is the phenomenon whereby surfaces in contact with water are colonized by microorganisms, which are ubiquitous in our environment. However, the economic implications of biofouling in industrial water systems are much greater than many people realize. In a survey conducted by the National Association of Corrosion Engineers of the United States ten years ago, it was found that many corrosion engineer did not accept the role of bacteria in corrosion, and many of then that did, could not recognize and mitigate the problem. Biofouling can be described in terms of its effects on processes and products such as material degradation (bio-corossion), product contamination, mechanical blockages, and impedance of heat transfer. Microorganisms distinguish themselves from other industrial water contaminants by their ability to utilize available nutrient sources, reproduce, and generate intra- and extracellular organic and inorganic substances in water. A sound understanding of the molecular and physiological activities of the microorganisms involved is necessary before strategies for the long term control of biofouling can be format. Traditional water treatment strategies however, have largely failed to address those factors that promote biofouling activities and lead to biocorrosion. Some of the major developments in recent years have been a redefinition of biofilm architecture and the realization that MIC of metals can be best understood as biomineralization.

  19. Technology for NPP decantate treatment realized at Kola NPP

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Stakhiv, Michael; Avezniyazov, Slava; Savkin, Alexander

    2007-07-01

    At Moscow SIA 'Radon' jointly with JSC 'Alliance Gamma', the technology for NPP Decantate Treatment was developed, tested and realized at Kola NPP. This technology consists of dissolving the salt residue and subsequent treatment by ozonization, separation of the deposits formed from ozonization and selective cleaning by ferro-cyanide sorbents. The nonactive salt solution goes to an industrial waste disposal site or a repository specially developed at NPP sites for 'exempt waste' products by IAEA classification. This technology was realized at Kola NPP in December 2006 year. At this time more than 1000 m{sup 3} of decantates log time stored aremore » treated. It allows solving very old problem to empty decantates' tanks at NPPs in environmentally safe manner and with high volume reduction factor. (authors)« less

  20. Four strategies for the age of smart services.

    PubMed

    Allmendinger, Glen; Lombreglia, Ralph

    2005-10-01

    Most industrial manufacturers realize that the real money isn't in products but in services. Companies such as General Electric and IBM have famously made the transition: A large proportion of their revenues and margins come from providing value-added services to customers. But other companies attempting to do the same might miss the boat. It is not enough, the authors say, just to provide services. Businesses must now provide "smart services"--building intelligence (awareness and connectivity) into the products themselves. Citing examples such as Heidelberger Druckmaschinen's Internet-connected printing presses and Eaton Electrical's home-monitoring service, the authors demonstrate how a product that can report its status back to its maker represents an opportunity for the manufacturer to cultivate richer, longer-term relationships with customers. Four business models will emerge in this new, networked world. If you go it alone, it may be as an embedded innovator- that is, your networked product sends back information that can help you optimize service delivery, eliminate waste and inefficiency, and raise service margins. Or, you may pursue a more aggressive solutionist business model- that is, you position your networked product as a "complete solution provider," able to deliver a broader scope of high-value services than those provided by the embedded innovator's product. In the case of a system that aggregates and processes data from multiple products in a building or home, you may be either an aggregator or a synergist, partnering with others to pursue a smart-services opportunity. An aggregator's product is the hub, collecting and processing usage information- and creating a high-value body of data. A synergist's product is the spoke, contributing valuable data or functionality. Woe to the company that takes none of these paths; it'll soon find its former customers locked in--and happily--to other smart service providers.

Top