[Pharmaceutical product quality control and good manufacturing practices].

PubMed

Hiyama, Yukio

2010-01-01

This report describes the roles of Good Manufacturing Practices (GMP) in pharmaceutical product quality control. There are three keys to pharmaceutical product quality control. They are specifications, thorough product characterization during development, and adherence to GMP as the ICH Q6A guideline on specifications provides the most important principles in its background section. Impacts of the revised Pharmaceutical Affairs Law (rPAL) which became effective in 2005 on product quality control are discussed. Progress of ICH discussion for Pharmaceutical Development (Q8), Quality Risk Management (Q9) and Pharmaceutical Quality System (Q10) are reviewed. In order to reconstruct GMP guidelines and GMP inspection system in the regulatory agencies under the new paradigm by rPAL and the ICH, a series of Health Science studies were conducted. For GMP guidelines, product GMP guideline, technology transfer guideline, laboratory control guideline and change control system guideline were written. For the GMP inspection system, inspection check list, inspection memo and inspection scenario were proposed also by the Health Science study groups. Because pharmaceutical products and their raw materials are manufactured and distributed internationally, collaborations with other national authorities are highly desired. In order to enhance the international collaborations, consistent establishment of GMP inspection quality system throughout Japan will be essential.

Modeling and control for closed environment plant production systems

NASA Technical Reports Server (NTRS)

Fleisher, David H.; Ting, K. C.; Janes, H. W. (Principal Investigator)

2002-01-01

A computer program was developed to study multiple crop production and control in controlled environment plant production systems. The program simulates crop growth and development under nominal and off-nominal environments. Time-series crop models for wheat (Triticum aestivum), soybean (Glycine max), and white potato (Solanum tuberosum) are integrated with a model-based predictive controller. The controller evaluates and compensates for effects of environmental disturbances on crop production scheduling. The crop models consist of a set of nonlinear polynomial equations, six for each crop, developed using multivariate polynomial regression (MPR). Simulated data from DSSAT crop models, previously modified for crop production in controlled environments with hydroponics under elevated atmospheric carbon dioxide concentration, were used for the MPR fitting. The model-based predictive controller adjusts light intensity, air temperature, and carbon dioxide concentration set points in response to environmental perturbations. Control signals are determined from minimization of a cost function, which is based on the weighted control effort and squared-error between the system response and desired reference signal.

Expert database system for quality control

NASA Astrophysics Data System (ADS)

Wang, Anne J.; Li, Zhi-Cheng

1993-09-01

There are more competitors today. Markets are not homogeneous they are fragmented into increasingly focused niches requiring greater flexibility in the product mix shorter manufacturing production runs and above allhigher quality. In this paper the author identified a real-time expert system as a way to improve plantwide quality management. The quality control expert database system (QCEDS) by integrating knowledge of experts in operations quality management and computer systems use all information relevant to quality managementfacts as well as rulesto determine if a product meets quality standards. Keywords: expert system quality control data base

Solar Powered Automated Pipe Water Management System, Water Footprint and Carbon Footprint in Soybean Production

NASA Astrophysics Data System (ADS)

Satyanto, K. S.; Abang, Z. E.; Arif, C.; Yanuar, J. P. M.

2018-05-01

An automatic water management system for agriculture land was developed based on mini PC as controller to manage irrigation and drainage. The system was integrated with perforated pipe network installed below the soil surface to enable water flow in and out through the network, and so water table of the land can be set at a certain level. The system was operated by using solar power electricity supply to power up water level and soil moisture sensors, Raspberry Pi controller and motorized valve actuator. This study aims to implement the system in controlling water level at a soybean production land, and further to observe water footprint and carbon footprint contribution of the soybean production process with application of the automated system. The water level of the field can be controlled around 19 cm from the base. Crop water requirement was calculated using Penman-Monteith approach, with the productivity of soybean 3.57t/ha, total water footprint in soybean production is 872.01 m3/t. Carbon footprint was calculated due to the use of solar power electric supply system and during the soybean production emission was estimated equal to 1.85 kg of CO2.

Propelled abrasive grit applications for weed management in transitional corn grain production systems

USDA-ARS?s Scientific Manuscript database

Weed control is challenging to farmers who are transitioning from production systems that use synthetic herbicides to organic systems. A two-year field study examined weed control efficacy and corn grain yield of air-propelled corncob grit abrasion for in-row weed control. Grits were applied based o...

Research Perspectives for Material Requirements Planning Systems. Paper No. 434.

ERIC Educational Resources Information Center

Berry, W. L.; Whybark, D. Clay

Material requirements planning (MRP) systems are described as management tools for planning and controlling production operations. A wide variety of industries and production organizations are credited as reporting significant operating improvements in such areas as inventory control, production scheduling, delivery performance, and production…

Serotonin Affects Movement Gain Control in the Spinal Cord

PubMed Central

Glaser, Joshua I.; Deng, Linna; Thompson, Christopher K.; Stevenson, Ian H.; Wang, Qining; Hornby, Thomas George; Heckman, Charles J.; Kording, Konrad P.

2014-01-01

A fundamental challenge for the nervous system is to encode signals spanning many orders of magnitude with neurons of limited bandwidth. To meet this challenge, perceptual systems use gain control. However, whether the motor system uses an analogous mechanism is essentially unknown. Neuromodulators, such as serotonin, are prime candidates for gain control signals during force production. Serotonergic neurons project diffusely to motor pools, and, therefore, force production by one muscle should change the gain of others. Here we present behavioral and pharmaceutical evidence that serotonin modulates the input–output gain of motoneurons in humans. By selectively changing the efficacy of serotonin with drugs, we systematically modulated the amplitude of spinal reflexes. More importantly, force production in different limbs interacts systematically, as predicted by a spinal gain control mechanism. Psychophysics and pharmacology suggest that the motor system adopts gain control mechanisms, and serotonin is a primary driver for their implementation in force production. PMID:25232107

Fuzzy logic control of rotating drum bioreactor for improved production of amylase and protease enzymes by Aspergillus oryzae in solid-state fermentation.

PubMed

Sukumprasertsri, Monton; Unrean, Pornkamol; Pimsamarn, Jindarat; Kitsubun, Panit; Tongta, Anan

2013-03-01

In this study, we compared the performance of two control systems, fuzzy logic control (FLC) and conventional control (CC). The control systems were applied for controlling temperature and substrate moisture content in a solidstate fermentation for the biosynthesis of amylase and protease enzymes by Aspergillus oryzae. The fermentation process was achieved in a 200 L rotating drum bioreactor. Three factors affecting temperature and moisture content in the solid-state fermentation were considered. They were inlet air velocity, speed of the rotating drum bioreactor, and spray water addition. The fuzzy logic control system was designed using four input variables: air velocity, substrate temperature, fermentation time, and rotation speed. The temperature was controlled by two variables, inlet air velocity and rotational speed of bioreactor, while the moisture content was controlled by spray water. Experimental results confirmed that the FLC system could effectively control the temperature and moisture content of substrate better than the CC system, resulting in an increased enzyme production by A. oryzae. Thus, the fuzzy logic control is a promising control system that can be applied for enhanced production of enzymes in solidstate fermentation.

An RFID-Based Manufacturing Control Framework for Loosely Coupled Distributed Manufacturing System Supporting Mass Customization

NASA Astrophysics Data System (ADS)

Chen, Ruey-Shun; Tsai, Yung-Shun; Tu, Arthur

In this study we propose a manufacturing control framework based on radio-frequency identification (RFID) technology and a distributed information system to construct a mass-customization production process in a loosely coupled shop-floor control environment. On the basis of this framework, we developed RFID middleware and an integrated information system for tracking and controlling the manufacturing process flow. A bicycle manufacturer was used to demonstrate the prototype system. The findings of this study were that the proposed framework can improve the visibility and traceability of the manufacturing process as well as enhance process quality control and real-time production pedigree access. Using this framework, an enterprise can easily integrate an RFID-based system into its manufacturing environment to facilitate mass customization and a just-in-time production model.

Systematic Product Development of Control and Diagnosis Functionalities

NASA Astrophysics Data System (ADS)

Stetter, R.; Simundsson, A.

2017-01-01

In the scientific field of systematic product development a wide range of helpful methods, guidelines and tools were generated and published in recent years. Until now little special attention was given to design guidelines aiming at supporting product development engineers to design products that allow and support control or diagnosis functions. The general trend to ubiquitous computing and the first development steps towards cognitive systems as well as a general trend toward higher product safety, reliability and reduced total cost of ownership (TCO) in many engineering fields lead to a higher importance of control and diagnosis. In this paper a first attempt is made to formulate general valid guidelines how products can be developed in order to allow and to achieve effective and efficient control and diagnosis. The guidelines are elucidated on the example of an automated guided vehicle. One main concern of this paper is the integration of control and diagnosis functionalities into the development of complete systems which include mechanical, electrical and electronic subsystems. For the development of such systems the strategies, methods and tools of systematic product development have attracted significant attention during the last decades. Today, the functionality and safety of most products is to a large degree dependent on control and diagnosis functionalities. Still, there is comparatively little research concentrating on the integration of the development of these functionalities into the overall product development processes. The paper starts with a background describing Systematic Product Development. The second section deals with the product development of the sample product. The third part clarifies the notions monitoring, control and diagnosis. The following parts summarize some insights and formulate first hypotheses concerning control and diagnosis in Systematic Product Development.

A Machine Vision Quality Control System for Industrial Acrylic Fibre Production

NASA Astrophysics Data System (ADS)

Heleno, Paulo; Davies, Roger; Correia, Bento A. Brázio; Dinis, João

2002-12-01

This paper describes the implementation of INFIBRA, a machine vision system used in the quality control of acrylic fibre production. The system was developed by INETI under a contract with a leading industrial manufacturer of acrylic fibres. It monitors several parameters of the acrylic production process. This paper presents, after a brief overview of the system, a detailed description of the machine vision algorithms developed to perform the inspection tasks unique to this system. Some of the results of online operation are also presented.

Network-based production quality control

NASA Astrophysics Data System (ADS)

Kwon, Yongjin; Tseng, Bill; Chiou, Richard

2007-09-01

This study investigates the feasibility of remote quality control using a host of advanced automation equipment with Internet accessibility. Recent emphasis on product quality and reduction of waste stems from the dynamic, globalized and customer-driven market, which brings opportunities and threats to companies, depending on the response speed and production strategies. The current trends in industry also include a wide spread of distributed manufacturing systems, where design, production, and management facilities are geographically dispersed. This situation mandates not only the accessibility to remotely located production equipment for monitoring and control, but efficient means of responding to changing environment to counter process variations and diverse customer demands. To compete under such an environment, companies are striving to achieve 100%, sensor-based, automated inspection for zero-defect manufacturing. In this study, the Internet-based quality control scheme is referred to as "E-Quality for Manufacturing" or "EQM" for short. By its definition, EQM refers to a holistic approach to design and to embed efficient quality control functions in the context of network integrated manufacturing systems. Such system let designers located far away from the production facility to monitor, control and adjust the quality inspection processes as production design evolves.

Management of herbicide resistance in wheat cropping systems: learning from the Australian experience.

PubMed

Walsh, Michael J; Powles, Stephen B

2014-09-01

Herbicide resistance continues to escalate in weed populations infesting global wheat (Triticum aestivum L.) crops, threatening grain production and thereby food supply. Conservation wheat production systems are reliant on the use of efficient herbicides providing low-cost, selective weed control in intensive cropping systems. The resistance-driven loss of herbicide resources combined with limited potential for new herbicide molecules means greater emphasis must be placed on preserving existing herbicides. For more than two decades, since the initial recognition of the dramatic consequences of herbicide resistance, the challenge of introducing additional weed control strategies into herbicide-based weed management programmes has been formidable. Throughout this period, herbicide resistance has expanded unabated across the world's wheat production regions. However, in Australia, where herbicide resources have become desperately depleted, the adoption of harvest weed seed control is evidence, at last, of a successful approach to sustainable weed management in wheat production systems. Growers routinely including strategies to target weed seeds during crop harvest, as part of herbicide-based weed management programmes, are now realising significant weed control and crop production benefits. When combined with an attitude of zero weed tolerance, there is evidence of a sustainable weed control future for wheat production systems. The hard-learned lessons of Australian growers can now be viewed by global wheat producers as an example of how to stop the continual loss of herbicide resources in productive cropping systems. © 2013 Society of Chemical Industry.

Process computerization of No. 13 blast furnace at Gary works

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sherman, G.J.; Zmierski, M.L.; Hyle, F.W.

1993-10-01

No. 13 blast furnace underwent extensive modifications to the process control system during the second reline. This represents a major shift in control philosophy from hardwired relays and analog controllers to a totally integrated computer control system. The new system created the opportunity for comprehensive diagnostic analysis and increased flexibility for control strategy modifications. The goal of achieving maximum production with minimal delay was accomplished by an integrated test, and comprehensive operator and maintenance training. Normal production was reached within four days of blow-ink and design production capacity of 7800 NTHM/day was met in the third month of operation. Recordmore » furnace productivity of 8931 NTHM/day (8.56 NTHM/100 crwv) was achieved in less than five months of operation and again in April 1992 of 9062 NTHM/day (8.68 NTHM/100 cfwv).« less

Cortical Interactions Underlying the Production of Speech Sounds

ERIC Educational Resources Information Center

Guenther, Frank H.

2006-01-01

Speech production involves the integration of auditory, somatosensory, and motor information in the brain. This article describes a model of speech motor control in which a feedforward control system, involving premotor and primary motor cortex and the cerebellum, works in concert with auditory and somatosensory feedback control systems that…

The maximization of the productivity of aquatic plants for use in controlled ecological life support systems (CELSS).

PubMed

Thompson, B G

1989-03-01

Lemna minor (common duckweed) and a Wolffia sp. were grown in submerged growth systems. Submerged growth increased the productivity unit volume (P/UV) of the organisms and may allow these plants to be used in a controlled ecological life support system (CELSS).

The maximization of the productivity of aquatic plants for use in controlled ecological life support systems (CELSS)

NASA Astrophysics Data System (ADS)

Thompson, B. G.

Lemna minor (common duckweed) and a Wolffia sp. were grown in submerged growth systems. Submerged growth increased the productivity/unit volume (P/UV) of the organisms and may allow these plants to be used in a controlled ecological life support system (CELSS).

Generation of control sequences for a pilot-disassembly system

NASA Astrophysics Data System (ADS)

Seliger, Guenther; Kim, Hyung-Ju; Keil, Thomas

2002-02-01

Closing the product and material cycles has emerged as a paradigm for industry in the 21st century. Disassembly plays a key role in a life cycle economy since it enables the recovery of resources. A partly automated disassembly system should adapt to a large variety of products and different degrees of devaluation. Also the amounts of products to be disassembled can vary strongly. To cope with these demands an approach to generate on-line disassembly control sequences will be presented. In order to react on these demands the technological feasibility is considered within a procedure for the generation of disassembly control sequences. Procedures are designed to find available and technologically feasible disassembly processes. The control system is formed by modularised and parameterised control units in the cell level within the entire control architecture. In the first development stage product and process analyses at the sample product washing machine were executed. Furthermore a generalized disassembly process was defined. Afterwards these processes were structured in primary and secondary functions. In the second stage the disassembly control at the technological level was investigated. Factors were the availability of the disassembly tools and the technological feasibility of the disassembly processes within the disassembly system. Technical alternative disassembly processes are determined as a result of availability of the tools and technological feasibility of processes. The fourth phase was the concept for the generation of the disassembly control sequences. The approach will be proved in a prototypical disassembly system.

Pulse-Flow Microencapsulation System

NASA Technical Reports Server (NTRS)

Morrison, Dennis R.

2006-01-01

The pulse-flow microencapsulation system (PFMS) is an automated system that continuously produces a stream of liquid-filled microcapsules for delivery of therapeutic agents to target tissues. Prior microencapsulation systems have relied on batch processes that involve transfer of batches between different apparatuses for different stages of production followed by sampling for acquisition of quality-control data, including measurements of size. In contrast, the PFMS is a single, microprocessor-controlled system that performs all processing steps, including acquisition of quality-control data. The quality-control data can be used as real-time feedback to ensure the production of large quantities of uniform microcapsules.

14 CFR 21.139 - Quality control.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Quality control. 21.139 Section 21.139... PROCEDURES FOR PRODUCTS AND PARTS Production Certificates § 21.139 Quality control. The applicant must show that he has established and can maintain a quality control system for any product, for which he...

14 CFR 21.139 - Quality control.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Quality control. 21.139 Section 21.139... PROCEDURES FOR PRODUCTS AND PARTS Production Certificates § 21.139 Quality control. The applicant must show that he has established and can maintain a quality control system for any product, for which he...

Flexible optical metrology strategies for the control and quality assurance of small series production

NASA Astrophysics Data System (ADS)

Schmitt, R.; Pavim, A.

2009-06-01

The demand for achieving smaller and more flexible production series with a considerable diversity of products complicates the control of the manufacturing tasks, leading to big challenges for the quality assurance systems. The quality assurance strategy that is nowadays used for mass production is unable to cope with the inspection flexibility needed among automated small series production, because the measuring strategy is totally dependent on the fixed features of the few manufactured object variants and on process parameters that can be controlled/compensated during production time. The major challenge faced by a quality assurance system applied to small series production facilities is to guarantee the needed quality level already at the first run, and therefore, the quality assurance system has to adapt itself constantly to the new manufacturing conditions. The small series production culture requires a change of paradigms, because its strategies are totally different from mass production. This work discusses the tight inspection requirements of small series production and presents flexible metrology strategies based on optical sensor data fusion techniques, agent-based systems as well as cognitive and self-optimised systems for assuring the needed quality level of flexible small series. Examples of application scenarios are provided among the automated assembly of solid state lasers and the flexible inspection of automotive headlights.

The development of small-scale mechanization means positioning algorithm using radio frequency identification technology in industrial plants

NASA Astrophysics Data System (ADS)

Astafiev, A.; Orlov, A.; Privezencev, D.

2018-01-01

The article is devoted to the development of technology and software for the construction of positioning and control systems for small mechanization in industrial plants based on radio frequency identification methods, which will be the basis for creating highly efficient intelligent systems for controlling the product movement in industrial enterprises. The main standards that are applied in the field of product movement control automation and radio frequency identification are considered. The article reviews modern publications and automation systems for the control of product movement developed by domestic and foreign manufacturers. It describes the developed algorithm for positioning of small-scale mechanization means in an industrial enterprise. Experimental studies in laboratory and production conditions have been conducted and described in the article.

PLC based automatic control of pasteurize mix in ice cream production

NASA Astrophysics Data System (ADS)

Yao, Xudong; Liang, Kai

2013-03-01

This paper describes the automatic control device of pasteurized mix in the ice cream production process.We design a scheme of control system using FBD program language and develop the programmer in the STEP 7-Micro/WIN software, check for any bugs before downloading into PLC .These developed devices will able to provide flexibility and accuracy to control the step of pasteurized mix. The operator just Input the duration and temperature of pasteurized mix through control panel. All the steps will finish automatically without any intervention in a preprogrammed sequence stored in programmable logic controller (PLC). With the help of this equipment we not only can control the quality of ice cream for various conditions, but also can simplify the production process. This control system is inexpensive and can be widely used in ice cream production industry.

77 FR 70724 - Eligibility of the Republic of Korea To Export Poultry Products to the United States

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-27

...) official controls over condemned product; (8) a Hazard Analysis and Critical Control Point (HACCP) system...) Hazard Analysis and Critical Control Point (HACCP) Systems, (5) Chemical Residue Testing Programs, and (6) Microbiological Testing Programs. FSIS evaluates the information submitted to verify that the critical points in...

TOXPERT: An Expert System for Risk Assessment

PubMed Central

Soto, R. J.; Osimitz, T. G.; Oleson, A.

1988-01-01

TOXPERT is an artificial intelligence based system used to model product safety, toxicology (TOX) and regulatory (REG) decision processes. An expert system shell uses backward chaining rule control to link “marketing approval” goals to the type of product, REG agency, exposure conditions and TOX. Marketing risks are primarily a function of the TOX, hazards and exposure potential. The method employed differentiates between REG requirements in goal seeking control for various types of products. This is accomplished by controlling rule execution by defining frames for each REG agency. In addition, TOXPERT produces classifications of TOX ratings and suggested product labeling. This production rule system uses principles of TOX, REGs, corporate guidelines and internal “rules of thumb.” TOXPERT acts as an advisor for this narrow domain. Advantages are that it can make routine decisions freeing professional's time for more complex problem solving, provide backup and training.

It Systems Supporting the Management of Production Capacity

NASA Astrophysics Data System (ADS)

Milewska, Elżbieta

2017-03-01

The paper presents the problem of manufacturing process flexibility in view of a company's material and information flow stream management. The author of the article has described the functions of a production process control system and presented the characteristics of production capacity intensive and extensive reserves. The MRP II/ERP, MES and APS class IT tools supporting the process of production planning, organization and control have also been discussed.

Toward More Productive Naval Shipbuilding

DTIC Science & Technology

1984-01-01

J. Seymour Exxon Production Research Scripps Institution of Oceanography •HeuiLon,.Tleas La Jolla, California William Creelman William H. Silcox...subassemblies move to become finished products. Figure 14 indicates the many organizational functions and physical steps through which information and...supplier control, and in some cases physical material control systems unique to its requirements. Systems developed along organizational linesuse some

Central Nervous System Control of Voice and Swallowing

PubMed Central

Ludlow, Christy L.

2015-01-01

This review of the central nervous control systems for voice and swallowing has suggested that the traditional concepts of a separation between cortical and limbic and brain stem control should be refined and more integrative. For voice production, a separation of the non-human vocalization system from the human learned voice production system has been posited based primarily on studies of non-human primates. However, recent humans studies of emotionally based vocalizations and human volitional voice production has shown more integration between these two systems than previously proposed. Recent human studies have shown that reflexive vocalization as well as learned voice production not involving speech, involve a common integrative system. On the other hand, recent studies of non-human primates have provided evidence of some cortical activity during vocalization and cortical changes with training during vocal behavior. For swallowing, evidence from the macaque and functional brain imaging in humans indicates that the control for the pharyngeal phase of swallowing is not primarily under brain stem mechanisms as previously proposed. Studies suggest that the initiation and patterning of swallowing for the pharyngeal phase is also under active cortical control for both spontaneous as well as volitional swallowing in awake humans and non-human primates. PMID:26241238

Design requirements for SRB production control system. Volume 2: System requirements and conceptual description

NASA Technical Reports Server (NTRS)

1981-01-01

In the development of the business system for the SRB automated production control system, special attention had to be paid to the unique environment posed by the space shuttle. The issues posed by this environment, and the means by which they were addressed, are reviewed. The change in management philosphy which will be required as NASA switches from one-of-a-kind launches to multiple launches is discussed. The implications of the assembly process on the business system are described. These issues include multiple missions, multiple locations and facilities, maintenance and refurbishment, multiple sources, and multiple contractors. The implications of these aspects on the automated production control system are reviewed including an assessment of the six major subsystems, as well as four other subsystem. Some general system requirements which flow through the entire business system are described.

[Study on "multi-dimensional structure and process dynamics quality control system" of Danshen infusion solution based on component structure theory].

PubMed

Feng, Liang; Zhang, Ming-Hua; Gu, Jun-Fei; Wang, Gui-You; Zhao, Zi-Yu; Jia, Xiao-Bin

2013-11-01

As traditional Chinese medicine (TCM) preparation products feature complex compounds and multiple preparation processes, the implementation of quality control in line with the characteristics of TCM preparation products provides a firm guarantee for the clinical efficacy and safety of TCM preparation products. Danshen infusion solution is a preparation commonly used in clinic, but its quality control is restricted to indexes of finished products, which can not guarantee its inherent quality. Our study group has proposed "multi-dimensional structure and process dynamics quality control system" on the basis of "component structure theory", for the purpose of controlling the quality of Danshen infusion solution at multiple levels and in multiple links from the efficacy-related material basis, the safety-related material basis, the characteristics of dosage form to the preparation process. This article, we bring forth new ideas and models to the quality control of TCM preparation products.

Use of artificial intelligence in the production of high quality minced meat

NASA Astrophysics Data System (ADS)

Kapovsky, B. R.; Pchelkina, V. A.; Plyasheshnik, P. I.; Dydykin, A. S.; Lazarev, A. A.

2017-09-01

A design for an automatic line for minced meat production according to new production technology based on an innovative meat milling method is proposed. This method allows the necessary degree of raw material comminution at the stage of raw material preparation to be obtained, which leads to production intensification due to the traditional meat mass comminution equipment being unnecessary. To ensure consistent quality of the product obtained, the use of on-line automatic control of the technological process for minced meat production is envisaged. This system has been developed using artificial intelligence methods and technologies. The system is trainable during the operation process, adapts to changes in processed raw material characteristics and to external impacts that affect the system operation, and manufactures meat shavings with minimal dispersion of the typical particle size. The control system includes equipment for express analysis of the chemical composition of the minced meat and its temperature after comminution. In this case, the minced meat production process can be controlled strictly as a function of time, which excludes subjective factors for assessing the degree of finished product readiness. This will allow finished meat products with consistent, targeted high quality to be produced.

Equipment modifications for perennial nutsedge control in fallow organic transition

USDA-ARS?s Scientific Manuscript database

Perennial nutsedges are extremely difficult to control in organic crop transition and production systems. Herbicides suitable for use in certified organic production do not adequately control perennial nutsedges. Cultural and mechanical control are partially effective in controlling perennial nuts...

[Establishment and application of "multi-dimensional structure and process dynamic quality control technology system" in preparation products of traditional Chinese medicine (I)].

PubMed

Gu, Jun-Fei; Feng, Liang; Zhang, Ming-Hua; Wu, Chan; Jia, Xiao-Bin

2013-11-01

Safety is an important component of the quality control of traditional Chinese medicine (TCM) preparation products, as well as an important guarantee for clinical application. Currently, the quality control of TCMs in Chinese Pharmacopoeia mostly focuses on indicative compounds for TCM efficacy. TCM preparations are associated with multiple links, from raw materials to products, and each procedure may have impacts on the safety of preparation. We make a summary and analysis on the factors impacting safety during the preparation of TCM products, and then expound the important role of the "multi-dimensional structure and process dynamic quality control technology system" in the quality safety of TCM preparations. Because the product quality of TCM preparation is closely related to the safety, the control over safety-related material basis is an important component of the product quality control of TCM preparations. The implementation of the quality control over the dynamic process of TCM preparations from raw materials to products, and the improvement of the TCM quality safety control at the microcosmic level help lay a firm foundation for the development of the modernization process of TCM preparations.

Design requirements for SRB production control system. Volume 1: Study background and overview

NASA Technical Reports Server (NTRS)

1981-01-01

The solid rocket boosters assembly environment is described in terms of the contraints it places upon an automated production control system. The business system generated for the SRB assembly and the computer system which meets the business system requirements are described. The selection software process and modifications required to the recommended software are addressed as well as the hardware and configuration requirements necessary to support the system.

On the Design of a Fuzzy Logic-Based Control System for Freeze-Drying Processes.

PubMed

Fissore, Davide

2016-12-01

This article is focused on the design of a fuzzy logic-based control system to optimize a drug freeze-drying process. The goal of the system is to keep product temperature as close as possible to the threshold value of the formulation being processed, without trespassing it, in such a way that product quality is not jeopardized and the sublimation flux is maximized. The method involves the measurement of product temperature and a set of rules that have been obtained through process simulation with the goal to obtain a unique set of rules for products with very different characteristics. Input variables are the difference between the temperature of the product and the threshold value, the difference between the temperature of the heating fluid and that of the product, and the rate of change of product temperature. The output variables are the variation of the temperature of the heating fluid and the pressure in the drying chamber. The effect of the starting value of the input variables and of the control interval has been investigated, thus resulting in the optimal configuration of the control system. Experimental investigation carried out in a pilot-scale freeze-dryer has been carried out to validate the proposed system. Copyright © 2016 American Pharmacists Association®. Published by Elsevier Inc. All rights reserved.

Establishing a Quality Control System for Stem Cell-Based Medicinal Products in China

PubMed Central

2015-01-01

Stem cell-based medicinal products (SCMPs) are emerging as novel therapeutic products. The success of its development depends on the existence of an effective quality control system, which is constituted by quality control technologies, standards, reference materials, guidelines, and the associated management system in accordance with regulatory requirements along product lifespan. However, a worldwide, effective quality control system specific for SCMPs is still far from established partially due to the limited understanding of stem cell sciences and lack of quality control technologies for accurately assessing the safety and biological effectiveness of SCMPs before clinical use. Even though, based on the existing regulations and current stem cell sciences and technologies, initial actions toward the goal of establishing such a system have been taken as exemplified by recent development of new “interim guidelines” for governing quality control along development of SCMPs and new development of the associated quality control technologies in China. In this review, we first briefly introduced the major institutions involved in the regulation of cell substrates and therapeutic cell products in China and the existing regulatory documents and technical guidelines used as critical references for developing the new interim guidelines. With focus only on nonhematopoietic stem cells, we then discussed the principal quality attributes of SCMPs as well as our thinking of proper testing approaches to be established with relevant evaluation technologies to ensure all quality requirements of SCMPs along different manufacturing processes and development stages. At the end, some regulatory and technical challenges were also discussed with the conclusion that combined efforts should be taken to promote stem cell regulatory sciences to establish the effective quality control system for SCMPs. PMID:25471126

A fuzzy classifier system for process control

NASA Technical Reports Server (NTRS)

Karr, C. L.; Phillips, J. C.

1994-01-01

A fuzzy classifier system that discovers rules for controlling a mathematical model of a pH titration system was developed by researchers at the U.S. Bureau of Mines (USBM). Fuzzy classifier systems successfully combine the strengths of learning classifier systems and fuzzy logic controllers. Learning classifier systems resemble familiar production rule-based systems, but they represent their IF-THEN rules by strings of characters rather than in the traditional linguistic terms. Fuzzy logic is a tool that allows for the incorporation of abstract concepts into rule based-systems, thereby allowing the rules to resemble the familiar 'rules-of-thumb' commonly used by humans when solving difficult process control and reasoning problems. Like learning classifier systems, fuzzy classifier systems employ a genetic algorithm to explore and sample new rules for manipulating the problem environment. Like fuzzy logic controllers, fuzzy classifier systems encapsulate knowledge in the form of production rules. The results presented in this paper demonstrate the ability of fuzzy classifier systems to generate a fuzzy logic-based process control system.

Manufacturing Execution Systems: Examples of Performance Indicator and Operational Robustness Tools.

PubMed

Gendre, Yannick; Waridel, Gérard; Guyon, Myrtille; Demuth, Jean-François; Guelpa, Hervé; Humbert, Thierry

Manufacturing Execution Systems (MES) are computerized systems used to measure production performance in terms of productivity, yield, and quality. In the first part, performance indicator and overall equipment effectiveness (OEE), process robustness tools and statistical process control are described. The second part details some tools to help process robustness and control by operators by preventing deviations from target control charts. MES was developed by Syngenta together with CIMO for automation.

Design requirements for SRB production control system. Volume 3: Package evaluation, modification and hardware

NASA Technical Reports Server (NTRS)

1981-01-01

The software package evaluation was designed to analyze commercially available, field-proven, production control or manufacturing resource planning management technology and software package. The analysis was conducted by comparing SRB production control software requirements and conceptual system design to software package capabilities. The methodology of evaluation and the findings at each stage of evaluation are described. Topics covered include: vendor listing; request for information (RFI) document; RFI response rate and quality; RFI evaluation process; and capabilities versus requirements.

ASSESSMENT OF A WIND TURBINE INTELLIGENT CONTROLLER FOR ENHANCED ENERGY PRODUCTION AND POLLUTION REDUCTION

EPA Science Inventory

This study assessed the enhanced energy production which is possible when variable-speed wind turbines are electronically controlled by an intelligent controller for efficiency optimization and performance improvement. The control system consists of three fuzzy- logic controllers...

Optimal strategy analysis based on robust predictive control for inventory system with random demand

NASA Astrophysics Data System (ADS)

Saputra, Aditya; Widowati, Sutrisno

2017-12-01

In this paper, the optimal strategy for a single product single supplier inventory system with random demand is analyzed by using robust predictive control with additive random parameter. We formulate the dynamical system of this system as a linear state space with additive random parameter. To determine and analyze the optimal strategy for the given inventory system, we use robust predictive control approach which gives the optimal strategy i.e. the optimal product volume that should be purchased from the supplier for each time period so that the expected cost is minimal. A numerical simulation is performed with some generated random inventory data. We simulate in MATLAB software where the inventory level must be controlled as close as possible to a set point decided by us. From the results, robust predictive control model provides the optimal strategy i.e. the optimal product volume that should be purchased and the inventory level was followed the given set point.

Control of Parts Shipped Prior to Type Certificate Issuance

DOT National Transportation Integrated Search

1992-10-14

This advisory circular provides information and guidance concerning the control of parts proposed to be shipped by manufacturers with an approved production inspection system (APIS) or production certificate (PC) (production approval : holders) in ad...

Synthetic biology and regulatory networks: where metabolic systems biology meets control engineering

PubMed Central

He, Fei; Murabito, Ettore; Westerhoff, Hans V.

2016-01-01

Metabolic pathways can be engineered to maximize the synthesis of various products of interest. With the advent of computational systems biology, this endeavour is usually carried out through in silico theoretical studies with the aim to guide and complement further in vitro and in vivo experimental efforts. Clearly, what counts is the result in vivo, not only in terms of maximal productivity but also robustness against environmental perturbations. Engineering an organism towards an increased production flux, however, often compromises that robustness. In this contribution, we review and investigate how various analytical approaches used in metabolic engineering and synthetic biology are related to concepts developed by systems and control engineering. While trade-offs between production optimality and cellular robustness have already been studied diagnostically and statically, the dynamics also matter. Integration of the dynamic design aspects of control engineering with the more diagnostic aspects of metabolic, hierarchical control and regulation analysis is leading to the new, conceptual and operational framework required for the design of robust and productive dynamic pathways. PMID:27075000

Design of Control System for Flexible Packaging Bags Palletizing Production Line Based on PLC

NASA Astrophysics Data System (ADS)

Zheng, Huiping; Chen, Lin; Zhao, Xiaoming; Liu, Zhanyang

Flexible packaging bags palletizing production line is to put the bags in the required area according to particular order and size, in order to finish handling, storage, loading and unloading, transportation and other logistics work of goods. Flexible packaging bags palletizing line is composed of turning bags mechanism, shaping mechanism, indexing mechanism, marshalling mechanism, pushing bags mechanism, pressing bags mechanism, laminating mechanism, elevator, tray warehouse, tray conveyor and loaded tray conveyor. Whether the whole production line can smoothly run depends on each of the above equipment and precision control among them. In this paper the technological process and the control logic of flexible packaging bags palletizing production line is introduced. Palletizing process of the production line realized automation by means of a control system based on programmable logic controller (PLC). It has the advantages of simple structure, reliable and easy maintenance etc.

Design and construction of a photobioreactor for hydrogen production, including status in the field.

PubMed

Skjånes, Kari; Andersen, Uno; Heidorn, Thorsten; Borgvang, Stig A

Several species of microalgae and phototrophic bacteria are able to produce hydrogen under certain conditions. A range of different photobioreactor systems have been used by different research groups for lab-scale hydrogen production experiments, and some few attempts have been made to upscale the hydrogen production process. Even though a photobioreactor system for hydrogen production does require special construction properties (e.g., hydrogen tight, mixing by other means than bubbling with air), only very few attempts have been made to design photobioreactors specifically for the purpose of hydrogen production. We have constructed a flat panel photobioreactor system that can be used in two modes: either for the cultivation of phototrophic microorganisms (upright and bubbling) or for the production of hydrogen or other anaerobic products (mixing by "rocking motion"). Special emphasis has been taken to avoid any hydrogen leakages, both by means of constructional and material choices. The flat plate photobioreactor system is controlled by a custom-built control system that can log and control temperature, pH, and optical density and additionally log the amount of produced gas and dissolved oxygen concentration. This paper summarizes the status in the field of photobioreactors for hydrogen production and describes in detail the design and construction of a purpose-built flat panel photobioreactor system, optimized for hydrogen production in terms of structural functionality, durability, performance, and selection of materials. The motivations for the choices made during the design process and advantages/disadvantages of previous designs are discussed.

Robust iterative learning contouring controller with disturbance observer for machine tool feed drives.

PubMed

Simba, Kenneth Renny; Bui, Ba Dinh; Msukwa, Mathew Renny; Uchiyama, Naoki

2018-04-01

In feed drive systems, particularly machine tools, a contour error is more significant than the individual axial tracking errors from the view point of enhancing precision in manufacturing and production systems. The contour error must be within the permissible tolerance of given products. In machining complex or sharp-corner products, large contour errors occur mainly owing to discontinuous trajectories and the existence of nonlinear uncertainties. Therefore, it is indispensable to design robust controllers that can enhance the tracking ability of feed drive systems. In this study, an iterative learning contouring controller consisting of a classical Proportional-Derivative (PD) controller and disturbance observer is proposed. The proposed controller was evaluated experimentally by using a typical sharp-corner trajectory, and its performance was compared with that of conventional controllers. The results revealed that the maximum contour error can be reduced by about 37% on average. Copyright © 2018 ISA. Published by Elsevier Ltd. All rights reserved.

Central voice production and pathophysiology of spasmodic dysphonia.

PubMed

Mor, Niv; Simonyan, Kristina; Blitzer, Andrew

2018-01-01

Our ability to speak is complex, and the role of the central nervous system in controlling speech production is often overlooked in the field of otolaryngology. In this brief review, we present an integrated overview of speech production with a focus on the role of central nervous system. The role of central control of voice production is then further discussed in relation to the potential pathophysiology of spasmodic dysphonia (SD). Peer-review articles on central laryngeal control and SD were identified from PUBMED search. Selected articles were augmented with designated relevant publications. Publications that discussed central and peripheral nervous system control of voice production and the central pathophysiology of laryngeal dystonia were chosen. Our ability to speak is regulated by specialized complex mechanisms coordinated by high-level cortical signaling, brainstem reflexes, peripheral nerves, muscles, and mucosal actions. Recent studies suggest that SD results from a primary central disturbance associated with dysfunction at our highest levels of central voice control. The efficacy of botulinum toxin in treating SD may not be limited solely to its local effect on laryngeal muscles and also may modulate the disorder at the level of the central nervous system. Future therapeutic options that target the central nervous system may help modulate the underlying disorder in SD and allow clinicians to better understand the principal pathophysiology. NA.Laryngoscope, 128:177-183, 2018. © 2017 The American Laryngological, Rhinological and Otological Society, Inc.

Dual transcriptional-translational cascade permits cellular level tuneable expression control

PubMed Central

Morra, Rosa; Shankar, Jayendra; Robinson, Christopher J.; Halliwell, Samantha; Butler, Lisa; Upton, Mathew; Hay, Sam; Micklefield, Jason; Dixon, Neil

2016-01-01

The ability to induce gene expression in a small molecule dependent manner has led to many applications in target discovery, functional elucidation and bio-production. To date these applications have relied on a limited set of protein-based control mechanisms operating at the level of transcription initiation. The discovery, design and reengineering of riboswitches offer an alternative means by which to control gene expression. Here we report the development and characterization of a novel tunable recombinant expression system, termed RiboTite, which operates at both the transcriptional and translational level. Using standard inducible promoters and orthogonal riboswitches, a multi-layered modular genetic control circuit was developed to control the expression of both bacteriophage T7 RNA polymerase and recombinant gene(s) of interest. The system was benchmarked against a number of commonly used E. coli expression systems, and shows tight basal control, precise analogue tunability of gene expression at the cellular level, dose-dependent regulation of protein production rates over extended growth periods and enhanced cell viability. This novel system expands the number of E. coli expression systems for use in recombinant protein production and represents a major performance enhancement over and above the most widely used expression systems. PMID:26405200

Design of neural network model-based controller in a fed-batch microbial electrolysis cell reactor for bio-hydrogen gas production

NASA Astrophysics Data System (ADS)

Azwar; Hussain, M. A.; Abdul-Wahab, A. K.; Zanil, M. F.; Mukhlishien

2018-03-01

One of major challenge in bio-hydrogen production process by using MEC process is nonlinear and highly complex system. This is mainly due to the presence of microbial interactions and highly complex phenomena in the system. Its complexity makes MEC system difficult to operate and control under optimal conditions. Thus, precise control is required for the MEC reactor, so that the amount of current required to produce hydrogen gas can be controlled according to the composition of the substrate in the reactor. In this work, two schemes for controlling the current and voltage of MEC were evaluated. The controllers evaluated are PID and Inverse neural network (NN) controller. The comparative study has been carried out under optimal condition for the production of bio-hydrogen gas wherein the controller output is based on the correlation of optimal current and voltage to the MEC. Various simulation tests involving multiple set-point changes and disturbances rejection have been evaluated and the performances of both controllers are discussed. The neural network-based controller results in fast response time and less overshoots while the offset effects are minimal. In conclusion, the Inverse neural network (NN)-based controllers provide better control performance for the MEC system compared to the PID controller.

CELSS research and development program

NASA Technical Reports Server (NTRS)

Bubenheim, David

1990-01-01

Research in Controlled Ecological Life Support Systems (CELSS) conducted by NASA indicate that plant based systems are feasible candidates for human support in space. Ames has responsibility for research and development, systems integration and control, and space flight experiment portions of the CELSS program. Important areas for development of new methods and technologies are biomass production, waste processing, water purification, air revitalization, and food processing. For the plant system, the approach was to identify the flexibility and response time for the food, water, and oxygen production, and carbon dioxide consumption processes. Tremendous increases in productivity, compared with terrestrial agriculture, were realized. Waste processing research emphasizes recycle (transformation) of human wastes, trash, and inedible biomass to forms usable as inputs to the plant production system. Efforts to improve efficiency of the plant system, select new CELSS crops for a balanced diet, and initiate closed system research with the Crop Growth Research Chambers continue. The System Control and Integration program goal is to insure orchestrated system operation of the biological, physical, and chemical operation of the biological, physical, and chemical component processors of the CELSS. Space flight studies are planned to verify adequate operation of the system in reduced gravity or microgravity environments.

Exploring cover crops as carbon sources for anaerobic soil disinfestation in a vegetable production system

USDA-ARS?s Scientific Manuscript database

In a raised-bed plasticulture vegetable production system utilizing anaerobic soil disinfestation (ASD) in Florida field trials, pathogen, weed, and parasitic nematode control was equivalent to or better than the methyl bromide control. Molasses was used as the labile carbon source to stimulate micr...

[The main directions of improving the system of state accounting and control of radioactive substances and radioactive waste products].

PubMed

2012-01-01

This paper describes a modification of the basic directions of state accounting and control of radioactive substances and radioactive waste products, whose implementation will significantly improve the efficiency of its operation at the regional level. Selected areas are designed to improve accounting and control system for the submission of the enterprises established by the reporting forms, the quality of the information contained in them, as well as structures of information and process for collecting, analyzing and data processing concerning radioactive substances and waste products.

Potential for nutrient recovery and biogas production from blackwater, food waste and greywater in urban source control systems.

PubMed

Kjerstadius, H; Haghighatafshar, S; Davidsson, Å

2015-01-01

In the last decades, the focus on waste and wastewater treatment systems has shifted towards increased recovery of energy and nutrients. Separation of urban food waste (FW) and domestic wastewaters using source control systems could aid this increase; however, their effect on overall sustainability is unknown. To obtain indicators for sustainability assessments, five urban systems for collection, transport, treatment and nutrient recovery from blackwater, greywater and FW were investigated using data from implementations in Sweden or northern Europe. The systems were evaluated against their potential for biogas production and nutrient recovery by the use of mass balances for organic material, nutrients and metals over the system components. The resulting indicators are presented in units suitable for use in future sustainability studies or life-cycle assessment of urban waste and wastewater systems. The indicators show that source control systems have the potential to increase biogas production by more than 70% compared with a conventional system and give a high recovery of phosphorus and nitrogen as biofertilizer. The total potential increase in gross energy equivalence for source control systems was 20-100%; the greatest increase shown is for vacuum-based systems.

A Ground Systems Architecture Transition for a Distributed Operations System

NASA Technical Reports Server (NTRS)

Sellers, Donna; Pitts, Lee; Bryant, Barry

2003-01-01

The Marshall Space Flight Center (MSFC) Ground Systems Department (GSD) recently undertook an architecture change in the product line that serves the ISS program. As a result, the architecture tradeoffs between data system product lines that serve remote users versus those that serve control center flight control teams were explored extensively. This paper describes the resulting architecture that will be used in the International Space Station (ISS) payloads program, and the resulting functional breakdown of the products that support this architecture. It also describes the lessons learned from the path that was followed, as a migration of products cause the need to reevaluate the allocation of functions across the architecture. The result is a set of innovative ground system solutions that is scalable so it can support facilities of wide-ranging sizes, from a small site up to large control centers. Effective use of system automation, custom components, design optimization for data management, data storage, data transmissions, and advanced local and wide area networking architectures, plus the effective use of Commercial-Off-The-Shelf (COTS) products, provides flexible Remote Ground System options that can be tailored to the needs of each user. This paper offers a description of the efficiency and effectiveness of the Ground Systems architectural options that have been implemented, and includes successful implementation examples and lessons learned.

HILIS - A HIGH INTENSITY LIGHT SYSTEM FOR ALGAE FOOD PRODUCTION,

DTIC Science & Technology

ALGAE, PRODUCTION CONTROL), (*FOOD, FEASIBILITY STUDIES), CHLORELLA , CALORIMETRY, NUTRITION, MODEL TESTS, ILLUMINATION, BRIGHTNESS, TEMPERATURE CONTROL, HEAT TRANSFER, SPECTRUM SIGNATURES, TEST METHODS, TEST EQUIPMENT.

A Blood Bank Information Management System

PubMed Central

Farmer, James J.

1982-01-01

A computerized Blood Bank Management system is described. Features include product oriented data input, inventory control reports, product utilization reports, rapid retrieval of individual patient reports. Relative benefits of the system are discussed.

[A strategy of constructing the technological system for quality control of Chinese medicine based on process control and management].

PubMed

Cheng, Yi-Yu; Qian, Zhong-Zhi; Zhang, Bo-Li

2017-01-01

The current situation, bottleneck problems and severe challenges in quality control technology of Chinese Medicine (CM) are briefly described. It is presented to change the phenomenon related to the post-test as the main means and contempt for process control in drug regulation, reverse the situation of neglecting the development of process control and management technology for pharmaceutical manufacture and reconstruct the technological system for quality control of CM products. The regulation and technology system based on process control and management for controlling CM quality should be established to solve weighty realistic problems of CM industry from the root causes, including backwardness of quality control technology, weakness of quality risk control measures, poor reputation of product quality and so on. By this way, the obstacles from poor controllability of CM product quality could be broken. Concentrating on those difficult problems and weak links in the technical field of CM quality control, it is proposed to build CMC (Chemistry, Manufacturing and Controls) regulation for CM products with Chinese characteristics and promote the regulation international recognition as soon as possible. The CMC technical framework, which is clinical efficacy-oriented, manufacturing manner-centered and process control-focused, was designed. To address the clinical characteristics of traditional Chinese medicine (TCM) and the production feature of CM manufacture, it is suggested to establish quality control engineering for CM manufacturing by integrating pharmaceutical analysis, TCM chemistry, TCM pharmacology, pharmaceutical engineering, control engineering, management engineering and other disciplines. Further, a theoretical model of quality control engineering for CM manufacturing and the methodology of digital pharmaceutical engineering are proposed. A technology pathway for promoting CM standard and realizing the strategic goal of CM internationalization is elaborated. Copyright© by the Chinese Pharmaceutical Association.

Image processing system performance prediction and product quality evaluation

NASA Technical Reports Server (NTRS)

Stein, E. K.; Hammill, H. B. (Principal Investigator)

1976-01-01

The author has identified the following significant results. A new technique for image processing system performance prediction and product quality evaluation was developed. It was entirely objective, quantitative, and general, and should prove useful in system design and quality control. The technique and its application to determination of quality control procedures for the Earth Resources Technology Satellite NASA Data Processing Facility are described.

Controlling high-throughput manufacturing at the nano-scale

NASA Astrophysics Data System (ADS)

Cooper, Khershed P.

2013-09-01

Interest in nano-scale manufacturing research and development is growing. The reason is to accelerate the translation of discoveries and inventions of nanoscience and nanotechnology into products that would benefit industry, economy and society. Ongoing research in nanomanufacturing is focused primarily on developing novel nanofabrication techniques for a variety of applications—materials, energy, electronics, photonics, biomedical, etc. Our goal is to foster the development of high-throughput methods of fabricating nano-enabled products. Large-area parallel processing and highspeed continuous processing are high-throughput means for mass production. An example of large-area processing is step-and-repeat nanoimprinting, by which nanostructures are reproduced again and again over a large area, such as a 12 in wafer. Roll-to-roll processing is an example of continuous processing, by which it is possible to print and imprint multi-level nanostructures and nanodevices on a moving flexible substrate. The big pay-off is high-volume production and low unit cost. However, the anticipated cost benefits can only be realized if the increased production rate is accompanied by high yields of high quality products. To ensure product quality, we need to design and construct manufacturing systems such that the processes can be closely monitored and controlled. One approach is to bring cyber-physical systems (CPS) concepts to nanomanufacturing. CPS involves the control of a physical system such as manufacturing through modeling, computation, communication and control. Such a closely coupled system will involve in-situ metrology and closed-loop control of the physical processes guided by physics-based models and driven by appropriate instrumentation, sensing and actuation. This paper will discuss these ideas in the context of controlling high-throughput manufacturing at the nano-scale.

Wisdom Appliance Control System

NASA Astrophysics Data System (ADS)

Hendrick; Jheng, Jyun-Teng; Tsai, Chen-Chai; Liou, Jia-Wei; Wang, Zhi-Hao; Jong, Gwo-Jia

2017-07-01

Intelligent appliances wisdom involves security, home care, convenient and energy saving, but the home automation system is still one of the core unit, and also using micro-processing electronics technology to centralized and control the home electrical products and systems, such as: lighting, television, fan, air conditioning, stereo, it composed of front-controller systems and back-controller panels, user using front-controller to control command, and then through the back-controller to powered the device.

Optimization of industrial microorganisms: recent advances in synthetic dynamic regulators.

PubMed

Min, Byung Eun; Hwang, Hyun Gyu; Lim, Hyun Gyu; Jung, Gyoo Yeol

2017-01-01

Production of biochemicals by industrial fermentation using microorganisms requires maintaining cellular production capacity, because maximal productivity is economically important. High-productivity microbial strains can be developed using static engineering, but these may not maintain maximal productivity throughout the culture period as culture conditions and cell states change dynamically. Additionally, economic reasons limit heterologous protein expression using inducible promoters to prevent metabolic burden for commodity chemical and biofuel production. Recently, synthetic and systems biology has been used to design genetic circuits, precisely controlling gene expression or influencing genetic behavior toward a desired phenotype. Development of dynamic regulators can maintain cellular phenotype in a maximum production state in response to factors including cell concentration, oxygen, temperature, pH, and metabolites. Herein, we introduce dynamic regulators of industrial microorganism optimization and discuss metabolic flux fine control by dynamic regulators in response to metabolites or extracellular stimuli, robust production systems, and auto-induction systems using quorum sensing.

Metabolic regulation and maximal reaction optimization in the central metabolism of a yeast cell

NASA Astrophysics Data System (ADS)

Kasbawati, Gunawan, A. Y.; Hertadi, R.; Sidarto, K. A.

2015-03-01

Regulation of fluxes in a metabolic system aims to enhance the production rates of biotechnologically important compounds. Regulation is held via modification the cellular activities of a metabolic system. In this study, we present a metabolic analysis of ethanol fermentation process of a yeast cell in terms of continuous culture scheme. The metabolic regulation is based on the kinetic formulation in combination with metabolic control analysis to indicate the key enzymes which can be modified to enhance ethanol production. The model is used to calculate the intracellular fluxes in the central metabolism of the yeast cell. Optimal control is then applied to the kinetic model to find the optimal regulation for the fermentation system. The sensitivity results show that there are external and internal control parameters which are adjusted in enhancing ethanol production. As an external control parameter, glucose supply should be chosen in appropriate way such that the optimal ethanol production can be achieved. For the internal control parameter, we find three enzymes as regulation targets namely acetaldehyde dehydrogenase, pyruvate decarboxylase, and alcohol dehydrogenase which reside in the acetaldehyde branch. Among the three enzymes, however, only acetaldehyde dehydrogenase has a significant effect to obtain optimal ethanol production efficiently.

Improving fumigation efficiency by increasing drip-tape number and using low permeability film in raised-bed production systems

USDA-ARS?s Scientific Manuscript database

Drip fumigation is commonly used for controlling soilborne pests in raised-bed strawberry production systems in California. However, the high emission loss and poor pest control indicate that the current fumigation practice with two drip tapes and polyethylene film (PE) covering need to be improved....

76 FR 50748 - Information Collection Activity: Production Safety Systems, Revision of a Collection; Submitted...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-16

... Production Safety Systems. OMB Control Number: 1010-0059. Abstract: The Outer Continental Shelf (OCS) Lands..., precautions, and techniques sufficient to prevent or minimize the likelihood of blowouts, loss of well control... an identifiable non-Federal recipient above and beyond those which accrue to the public at large...

Automation and robotics - Key to productivity. [in industry and space

NASA Technical Reports Server (NTRS)

Cohen, A.

1985-01-01

The automated and robotic systems requirements of the NASA Space Station are prompted by maintenance, repair, servicing and assembly requirements. Trend analyses, fault diagnoses, and subsystem status assessments for the Station's electrical power, guidance, navigation, control, data management and environmental control subsystems will be undertaken by cybernetic expert systems; this will reduce or eliminate on-board or ground facility activities that would otherwise be essential, enhancing system productivity. Additional capabilities may also be obtained through the incorporation of even a limited amount of artificial intelligence in the controllers of the various Space Station systems.

Controlled Ecological Life Support System: Use of Higher Plants

NASA Technical Reports Server (NTRS)

Tibbits, T. W.; Alford, D. K.

1982-01-01

Results of two workshops concerning the use of higher plants in Controlled Ecological Life Support Systems (CELSS) are summarized. Criteria for plant selection were identified from these categories: food production, nutrition, oxygen production and carbon dioxide utilization, water recycling, waste recycling, and other morphological and physiological considerations. Types of plant species suitable for use in CELSS, growing procedures, and research priorities were recommended. Also included are productivity values for selected plant species.

Control and Diagnosis in Integrated Product Development - Observations during the Development of an AGV

NASA Astrophysics Data System (ADS)

Stetter, R.; Simundsson, A.

2015-11-01

This paper is concerned with the integration of control and diagnosis functionalities into the development of complete systems which include mechanical, electrical and electronic subsystems. For the development of such systems the strategies, methods and tools of integrated product development have attracted significant attention during the last decades. Today, it is generally observed that product development processes of complex systems can only be successful if the activities in the different domains are well connected and synchronised and if an ongoing communication is present - an ongoing communication spanning the technical domains and also including functions such as production planning, marketing/distribution, quality assurance, service and project planning. Obviously, numerous approaches to tackle this challenge are present in scientific literature and in industrial practice, as well. Today, the functionality and safety of most products is to a large degree dependent on control and diagnosis functionalities. Still, there is comparatively little research concentrating on the integration of the development of these functionalities into the overall product development processes. The main source of insight of the presented research is the product development process of an Automated Guided Vehicle (AGV) which is intended to be used on rough terrain. The paper starts with a background describing Integrated Product Development. The second section deals with the product development of the sample product. The third part summarizes some insights and formulates first hypotheses concerning control and diagnosis in Integrated Product Development.

21 CFR 111.135 - What quality control operations are required for product complaints?

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 2 2010-04-01 2010-04-01 false What quality control operations are required for... MANUFACTURING, PACKAGING, LABELING, OR HOLDING OPERATIONS FOR DIETARY SUPPLEMENTS Production and Process Control System: Requirements for Quality Control § 111.135 What quality control operations are required for...

Verification and Validation Challenges for Adaptive Flight Control of Complex Autonomous Systems

NASA Technical Reports Server (NTRS)

Nguyen, Nhan T.

2018-01-01

Autonomy of aerospace systems requires the ability for flight control systems to be able to adapt to complex uncertain dynamic environment. In spite of the five decades of research in adaptive control, the fact still remains that currently no adaptive control system has ever been deployed on any safety-critical or human-rated production systems such as passenger transport aircraft. The problem lies in the difficulty with the certification of adaptive control systems since existing certification methods cannot readily be used for nonlinear adaptive control systems. Research to address the notion of metrics for adaptive control began to appear in the recent years. These metrics, if accepted, could pave a path towards certification that would potentially lead to the adoption of adaptive control as a future control technology for safety-critical and human-rated production systems. Development of certifiable adaptive control systems represents a major challenge to overcome. Adaptive control systems with learning algorithms will never become part of the future unless it can be proven that they are highly safe and reliable. Rigorous methods for adaptive control software verification and validation must therefore be developed to ensure that adaptive control system software failures will not occur, to verify that the adaptive control system functions as required, to eliminate unintended functionality, and to demonstrate that certification requirements imposed by regulatory bodies such as the Federal Aviation Administration (FAA) can be satisfied. This presentation will discuss some of the technical issues with adaptive flight control and related V&V challenges.

Synthetic biology and regulatory networks: where metabolic systems biology meets control engineering.

PubMed

He, Fei; Murabito, Ettore; Westerhoff, Hans V

2016-04-01

Metabolic pathways can be engineered to maximize the synthesis of various products of interest. With the advent of computational systems biology, this endeavour is usually carried out through in silico theoretical studies with the aim to guide and complement further in vitro and in vivo experimental efforts. Clearly, what counts is the result in vivo, not only in terms of maximal productivity but also robustness against environmental perturbations. Engineering an organism towards an increased production flux, however, often compromises that robustness. In this contribution, we review and investigate how various analytical approaches used in metabolic engineering and synthetic biology are related to concepts developed by systems and control engineering. While trade-offs between production optimality and cellular robustness have already been studied diagnostically and statically, the dynamics also matter. Integration of the dynamic design aspects of control engineering with the more diagnostic aspects of metabolic, hierarchical control and regulation analysis is leading to the new, conceptual and operational framework required for the design of robust and productive dynamic pathways. © 2016 The Author(s).

Lumped versus distributed thermoregulatory control: results from a three-dimensional dynamic model.

PubMed

Werner, J; Buse, M; Foegen, A

1989-01-01

In this study we use a three-dimensional model of the human thermal system, the spatial grid of which is 0.5 ... 1.0 cm. The model is based on well-known physical heat-transfer equations, and all parameters of the passive system have definite physical values. According to the number of substantially different areas and organs, 54 spatially different values are attributed to each physical parameter. Compatibility of simulation and experiment was achieved solely on the basis of physical considerations and physiological basic data. The equations were solved using a modification of the alternating direction implicit method. On the basis of this complex description of the passive system close to reality, various lumped and distributed parameter control equations were tested for control of metabolic heat production, blood flow and sweat production. The simplest control equations delivering results on closed-loop control compatible with experimental evidence were determined. It was concluded that it is essential to take into account the spatial distribution of heat production, blood flow and sweat production, and that at least for control of shivering, distributed controller gains different from the pattern of distribution of muscle tissue are required. For sweat production this is not so obvious, so that for simulation of sweating control after homogeneous heat load a lumped parameter control may be justified. Based on these conclusions three-dimensional temperature profiles for cold and heat load and the dynamics for changes of the environmental conditions were computed. In view of the exact simulation of the passive system and the compatibility with experimentally attainable variables there is good evidence that those values extrapolated by the simulation are adequately determined. The model may be used both for further analysis of the real thermoregulatory mechanisms and for special applications in environmental and clinical health care.

14 CFR 21.147 - Changes in quality control system.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Changes in quality control system. 21.147 Section 21.147 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION... quality control system. After the issue of a production certificate, each change to the quality control...

14 CFR 21.147 - Changes in quality control system.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Changes in quality control system. 21.147 Section 21.147 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION... quality control system. After the issue of a production certificate, each change to the quality control...

[A design of simple ventilator control system based on LabVIEW].

PubMed

Pei, Baoqing; Xu, Shengwei; Li, Hui; Li, Deyu; Pei, Yidong; He, Haixing

2011-01-01

This paper designed a ventilator control system to control proportional valves and motors. It used LabVIEW to control the object mentioned above and design ,validate, evaluate arithmetic, and establish hardware in loop platform. There are two system' s hierarchies. The high layer was used to run non-real time program and the low layer was used to run real time program. The two layers communicated through TCP/IP net. The program can be divided into several modules, which can be expanded and maintained easily. And the harvest in the prototype designing can be seamlessly used to embedded products. From all above, this system was useful in employing OEM products.

Use of near-infrared spectroscopy and multipoint measurements for quality control of pharmaceutical drug products.

PubMed

Boiret, Mathieu; Chauchard, Fabien

2017-01-01

Near-infrared (NIR) spectroscopy is a non-destructive analytical technique that enables better-understanding and optimization of pharmaceutical processes and final drug products. The use in line is often limited by acquisition speed and sampling area. This work focuses on performing a multipoint measurement at high acquisition speed at the end of the manufacturing process on a conveyor belt system to control both the distribution and the content of active pharmaceutical ingredient within final drug products, i.e., tablets. A specially designed probe with several collection fibers was developed for this study. By measuring spectral and spatial information, it provides physical and chemical knowledge on the final drug product. The NIR probe was installed on a conveyor belt system that enables the analysis of a lot of tablets. The use of these NIR multipoint measurement probes on a conveyor belt system provided an innovative method that has the potential to be used as a new paradigm to ensure the drug product quality at the end of the manufacturing process and as a new analytical method for the real-time release control strategy. Graphical abstract Use of near-infrared spectroscopy and multipoint measurements for quality control of pharmaceutical drug products.

[Controlling systems for operating room managers].

PubMed

Schüpfer, G; Bauer, M; Scherzinger, B; Schleppers, A

2005-08-01

Management means developing, shaping and controlling of complex, productive and social systems. Therefore, operating room managers also need to develop basic skills in financial and managerial accounting as a basis for operative and strategic controlling which is an essential part of their work. A good measurement system should include financial and strategic concepts for market position, innovation performance, productivity, attractiveness, liquidity/cash flow and profitability. Since hospitals need to implement a strategy to reach their business objectives, the performance measurement system has to be individually adapted to the strategy of the hospital. In this respect the navigation system developed by Gälweiler is compared to the "balanced score card" system of Kaplan and Norton.

Implementation of Lean System on Erbium Doped Fibre Amplifier Manufacturing Process to Reduce Production Time

NASA Astrophysics Data System (ADS)

Maneechote, T.; Luangpaiboon, P.

2010-10-01

A manufacturing process of erbium doped fibre amplifiers is complicated. It needs to meet the customers' requirements under a present economic status that products need to be shipped to customers as soon as possible after purchasing orders. This research aims to study and improve processes and production lines of erbium doped fibre amplifiers using lean manufacturing systems via an application of computer simulation. Three scenarios of lean tooled box systems are selected via the expert system. Firstly, the production schedule based on shipment date is combined with a first in first out control system. The second scenario focuses on a designed flow process plant layout. Finally, the previous flow process plant layout combines with production schedule based on shipment date including the first in first out control systems. The computer simulation with the limited data via an expected value is used to observe the performance of all scenarios. The most preferable resulted lean tooled box systems from a computer simulation are selected to implement in the real process of a production of erbium doped fibre amplifiers. A comparison is carried out to determine the actual performance measures via an analysis of variance of the response or the production time per unit achieved in each scenario. The goodness of an adequacy of the linear statistical model via experimental errors or residuals is also performed to check the normality, constant variance and independence of the residuals. The results show that a hybrid scenario of lean manufacturing system with the first in first out control and flow process plant lay out statistically leads to better performance in terms of the mean and variance of production times.

Unified Information Access in Product Creation with an Integrated Control Desk

NASA Astrophysics Data System (ADS)

Wrasse, Kevin; Diener, Holger; Hayka, Haygazun; Stark, Rainer

2017-06-01

Customers demand for individualized products leads to a large variety of different products in small series and single-unit production. A high flexibility pressure in product creation is one result of this trend. In order to counteract the pressure, the information steadily increasing by Industry 4.0 must be made available at the workplace. Additionally, a better exchange of information between product development, production planning and production is necessary. The improvement of individual systems, like CAD, PDM, ERP and MES, can only achieve this to a limited extent. Since they mostly use systems from different manufacturers, the necessary deeper integration of information is only feasible for SMEs to a limited extend. The presented control desk helps to ensure a more flexible product creation as well as information exchange. It captures information from different IT systems in the production process and presents them integrated, task-oriented and oriented to the user’s mental model, e.g. information of the production combined with the 3D model of product parts, or information about product development on the 3D model of the production. The solution is a digital 3D model of the manufacturing environment, which is enriched by billboards for a quick information overview and web service windows to access detailed MES and PDM information. By this, the level of abstraction can be reduced and reacts to changed requirements in the short term, making informed decisions. The interaction with the control stands utilizes the touch skills of mobile and fixed systems such as smartphones, tablets and multitouch tables.

SCI Hazard Report Methodology

NASA Technical Reports Server (NTRS)

Mitchell, Michael S.

2010-01-01

This slide presentation reviews the methodology in creating a Source Control Item (SCI) Hazard Report (HR). The SCI HR provides a system safety risk assessment for the following Ares I Upper Stage Production Contract (USPC) components (1) Pyro Separation Systems (2) Main Propulsion System (3) Reaction and Roll Control Systems (4) Thrust Vector Control System and (5) Ullage Settling Motor System components.

Automatic Overset Grid Generation with Heuristic Feedback Control

NASA Technical Reports Server (NTRS)

Robinson, Peter I.

2001-01-01

An advancing front grid generation system for structured Overset grids is presented which automatically modifies Overset structured surface grids and control lines until user-specified grid qualities are achieved. The system is demonstrated on two examples: the first refines a space shuttle fuselage control line until global truncation error is achieved; the second advances, from control lines, the space shuttle orbiter fuselage top and fuselage side surface grids until proper overlap is achieved. Surface grids are generated in minutes for complex geometries. The system is implemented as a heuristic feedback control (HFC) expert system which iteratively modifies the input specifications for Overset control line and surface grids. It is developed as an extension of modern control theory, production rules systems and subsumption architectures. The methodology provides benefits over the full knowledge lifecycle of an expert system for knowledge acquisition, knowledge representation, and knowledge execution. The vector/matrix framework of modern control theory systematically acquires and represents expert system knowledge. Missing matrix elements imply missing expert knowledge. The execution of the expert system knowledge is performed through symbolic execution of the matrix algebra equations of modern control theory. The dot product operation of matrix algebra is generalized for heuristic symbolic terms. Constant time execution is guaranteed.

[Life support of the Mars exploration crew. Control of a zeolite system for carbon dioxide removal from space cabin air within a closed air regeneration cycle].

PubMed

Chekov, Iu F

2009-01-01

The author describes a zeolite system for carbon dioxide removal integrated into a closed air regeneration cycle aboard spacecraft. The continuous operation of a double-adsorbent regeneration system with pCO2-dependable productivity is maintained through programmable setting of adsorption (desorption) semicycle time. The optimal system regulation curve is presented within the space of statistical performance family obtained in quasi-steady operating modes with controlled parameters of the recurrent adsorption-desorption cycle. The automatically changing system productivity ensures continuous intake of concentrated CO2. Control of the adsorption-desorption process is based on calculation of the differential adsorption (desorption) heat from gradient of adsorbent and test inert substance temperatures. The adaptive algorithm of digital control is implemented through the standard spacecraft interface with the board computer system and programmable microprocessor-based controllers.

Development of a Production Ready Automated Wire Delivery System

NASA Technical Reports Server (NTRS)

1997-01-01

The current development effort is a Phase 3 research study entitled "A Production Ready Automated Wire Delivery System", contract number NAS8-39933, awarded to Nichols Research Corporation (NRC). The goals of this research study were to production harden the existing Automated Wire Delivery (AWDS) motion and sensor hardware and test the modified AWDS in a range of welding applications. In addition, the prototype AWDS controller would be moved to the VME bus platform by designing, fabricating and testing a single board VME bus AWDS controller. This effort was to provide an AWDS that could transition from the laboratory environment to production operations. The project was performed in two development steps. Step 1 modified and tested an improved MWG. Step 2 developed and tested the AWDS single board VME bus controller. Step 3 installed the Wire Pilot in a Weld Controller with the imbedded VME bus controller.

A quality system for PET: An industry perspective

NASA Astrophysics Data System (ADS)

Zigler, Steven S.; Breslow, Kenneth; Nazerias, Michael

2005-12-01

Quality systems have been employed in a variety of industries to develop and supply products that meet customer expectations and regulatory requirements. Most quality systems address organizational structure, design controls, production, complaints, audits, corrective actions and preventive actions. This paper describes PETNET's efforts to develop a quality system for use in the production of PET tracers. Our goal is to ensure quality products and to facilitate compliance with impending PET good manufacturing practice (GMP) regulations.

GIS and RDBMS Used with Offline FAA Airspace Databases

NASA Technical Reports Server (NTRS)

Clark, J.; Simmons, J.; Scofield, E.; Talbott, B.

1994-01-01

A geographic information system (GIS) and relational database management system (RDBMS) were used in a Macintosh environment to access, manipulate, and display off-line FAA databases of airport and navigational aid locations, airways, and airspace boundaries. This proof-of-concept effort used data available from the Adaptation Controlled Environment System (ACES) and Digital Aeronautical Chart Supplement (DACS) databases to allow FAA cartographers and others to create computer-assisted charts and overlays as reference material for air traffic controllers. These products were created on an engineering model of the future GRASP (GRaphics Adaptation Support Position) workstation that will be used to make graphics and text products for the Advanced Automation System (AAS), which will upgrade and replace the current air traffic control system. Techniques developed during the prototyping effort have shown the viability of using databases to create graphical products without the need for an intervening data entry step.

40 CFR 420.12 - Effluent limitations representing the degree of effluent reduction attainable by the application...

Code of Federal Regulations, 2010 CFR

2010-07-01

... best practicable control technology currently available. (a) By-product cokemaking—iron and steel... for by-product coke plants which have wet desulfurization systems but only to the extent such systems... limitations, are allowed for by-product coke plants which include indirect ammonia recovery systems but only...

[Introduction of hazard analysis and critical control points (HACCP) principles at the flight catering food production plant].

PubMed

Popova, A Yu; Trukhina, G M; Mikailova, O M

In the article there is considered the quality control and safety system implemented in the one of the largest flight catering food production plant for airline passengers and flying squad. The system for the control was based on the Hazard Analysis And Critical Control Points (HACCP) principles and developed hygienic and antiepidemic measures. There is considered the identification of hazard factors at stages of the technical process. There are presented results of the analysis data of monitoring for 6 critical control points over the five-year period. The quality control and safety system permit to decline food contamination risk during acceptance, preparation and supplying of in-flight meal. There was proved the efficiency of the implemented system. There are determined further ways of harmonization and implementation for HACCP principles in the plant.

How gamma radiation processing systems are benefiting from the latest advances in information technology

NASA Astrophysics Data System (ADS)

Gibson, Wayne H.; Levesque, Daniel

2000-03-01

This paper discusses how gamma irradiation plants are putting the latest advances in computer and information technology to use for better process control, cost savings, and strategic advantages. Some irradiator operations are gaining significant benefits by integrating computer technology and robotics with real-time information processing, multi-user databases, and communication networks. The paper reports on several irradiation facilities that are making good use of client/server LANs, user-friendly graphics interfaces, supervisory control and data acquisition (SCADA) systems, distributed I/O with real-time sensor devices, trending analysis, real-time product tracking, dynamic product scheduling, and automated dosimetry reading. These plants are lowering costs by fast and reliable reconciliation of dosimetry data, easier validation to GMP requirements, optimizing production flow, and faster release of sterilized products to market. There is a trend in the manufacturing sector towards total automation using "predictive process control". Real-time verification of process parameters "on-the-run" allows control parameters to be adjusted appropriately, before the process strays out of limits. Applying this technology to the gamma radiation process, control will be based on monitoring the key parameters such as time, and making adjustments during the process to optimize quality and throughput. Dosimetry results will be used as a quality control measurement rather than as a final monitor for the release of the product. Results are correlated with the irradiation process data to quickly and confidently reconcile variations. Ultimately, a parametric process control system utilizing responsive control, feedback and verification will not only increase productivity and process efficiency, but can also result in operating within tighter dose control set points.

Object positioning in storages of robotized workcells using LabVIEW Vision

NASA Astrophysics Data System (ADS)

Hryniewicz, P.; Banaś, W.; Sękala, A.; Gwiazda, A.; Foit, K.; Kost, G.

2015-11-01

During the manufacturing process, each performed task is previously developed and adapted to the conditions and the possibilities of the manufacturing plant. The production process is supervised by a team of specialists because any downtime causes great loss of time and hence financial loss. Sensors used in industry for tracking and supervision various stages of a production process make it much easier to maintain it continuous. One of groups of sensors used in industrial applications are non-contact sensors. This group includes: light barriers, optical sensors, rangefinders, vision systems, and ultrasonic sensors. Through to the rapid development of electronics the vision systems were widespread as the most flexible type of non-contact sensors. These systems consist of cameras, devices for data acquisition, devices for data analysis and specialized software. Vision systems work well as sensors that control the production process itself as well as the sensors that control the product quality level. The LabVIEW program as well as the LabVIEW Vision and LabVIEW Builder represent the application that enables program the informatics system intended to process and product quality control. The paper presents elaborated application for positioning elements in a robotized workcell. Basing on geometric parameters of manipulated object or on the basis of previously developed graphical pattern it is possible to determine the position of particular manipulated elements. This application could work in an automatic mode and in real time cooperating with the robot control system. It allows making the workcell functioning more autonomous.

Managing computer-controlled operations

NASA Technical Reports Server (NTRS)

Plowden, J. B.

1985-01-01

A detailed discussion of Launch Processing System Ground Software Production is presented to establish the interrelationships of firing room resource utilization, configuration control, system build operations, and Shuttle data bank management. The production of a test configuration identifier is traced from requirement generation to program development. The challenge of the operational era is to implement fully automated utilities to interface with a resident system build requirements document to eliminate all manual intervention in the system build operations. Automatic update/processing of Shuttle data tapes will enhance operations during multi-flow processing.

48 CFR 870.111-5 - Frozen processed food products.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 5 2014-10-01 2014-10-01 false Frozen processed food... DEPARTMENT SUPPLEMENTARY REGULATIONS SPECIAL PROCUREMENT CONTROLS Controls 870.111-5 Frozen processed food products. (a) The following frozen processed food products must have a label complying with the Federal...

48 CFR 870.111-5 - Frozen processed food products.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Frozen processed food... DEPARTMENT SUPPLEMENTARY REGULATIONS SPECIAL PROCUREMENT CONTROLS Controls 870.111-5 Frozen processed food products. (a) The following frozen processed food products must have a label complying with the Federal...

48 CFR 870.111-5 - Frozen processed food products.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 5 2012-10-01 2012-10-01 false Frozen processed food... DEPARTMENT SUPPLEMENTARY REGULATIONS SPECIAL PROCUREMENT CONTROLS Controls 870.111-5 Frozen processed food products. (a) The following frozen processed food products must have a label complying with the Federal...

48 CFR 870.111-5 - Frozen processed food products.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Frozen processed food... DEPARTMENT SUPPLEMENTARY REGULATIONS SPECIAL PROCUREMENT CONTROLS Controls 870.111-5 Frozen processed food products. (a) The following frozen processed food products must have a label complying with the Federal...

48 CFR 870.111-5 - Frozen processed food products.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 5 2013-10-01 2013-10-01 false Frozen processed food... DEPARTMENT SUPPLEMENTARY REGULATIONS SPECIAL PROCUREMENT CONTROLS Controls 870.111-5 Frozen processed food products. (a) The following frozen processed food products must have a label complying with the Federal...

A pulse-width modulated, high reliability charge controller for small photovoltaic systems

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gerken, K.; Welsh, D.

1997-02-01

This report presents the results of a development effort to design, test and begin production of a new class of small photovoltaic (PV) charge controllers. Sandia National Laboratories provided technical support, test data and financial support through a Balance-of-System Development contract. One of the objectives of the development was to increase user confidence in small PV systems by improving the reliability and operating life of the system controllers. Another equally important objective was to improve the economics of small PV systems by extending the battery lifetimes. Using new technology and advanced manufacturing techniques, these objectives were accomplished. Because small stand-alonemore » PV systems account for over one third of all PV modules shipped, the positive impact of improving the reliability and economics of PV systems in this market segment will be felt throughout the industry. The results of verification testing of the new product are also included in this report. The initial design goals and specifications were very aggressive, but the extensive testing demonstrates that all the goals were achieved. Production of the product started in May at a rate of 2,000 units per month. Over 40 Morningstar distributors (5 US and 35 overseas) have taken delivery in the first 2 months of shipments. Initial customer reactions to the new controller have been very favorable.« less

9 CFR 417.6 - Inadequate HACCP Systems.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Inadequate HACCP Systems. 417.6 Section 417.6 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE... ANALYSIS AND CRITICAL CONTROL POINT (HACCP) SYSTEMS § 417.6 Inadequate HACCP Systems. A HACCP system may be...

9 CFR 417.6 - Inadequate HACCP Systems.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 9 Animals and Animal Products 2 2014-01-01 2014-01-01 false Inadequate HACCP Systems. 417.6 Section 417.6 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE... ANALYSIS AND CRITICAL CONTROL POINT (HACCP) SYSTEMS § 417.6 Inadequate HACCP Systems. A HACCP system may be...

9 CFR 417.6 - Inadequate HACCP Systems.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 9 Animals and Animal Products 2 2013-01-01 2013-01-01 false Inadequate HACCP Systems. 417.6 Section 417.6 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE... ANALYSIS AND CRITICAL CONTROL POINT (HACCP) SYSTEMS § 417.6 Inadequate HACCP Systems. A HACCP system may be...

9 CFR 417.6 - Inadequate HACCP Systems.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 9 Animals and Animal Products 2 2011-01-01 2011-01-01 false Inadequate HACCP Systems. 417.6 Section 417.6 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE... ANALYSIS AND CRITICAL CONTROL POINT (HACCP) SYSTEMS § 417.6 Inadequate HACCP Systems. A HACCP system may be...

9 CFR 417.6 - Inadequate HACCP Systems.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 9 Animals and Animal Products 2 2012-01-01 2012-01-01 false Inadequate HACCP Systems. 417.6 Section 417.6 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE... ANALYSIS AND CRITICAL CONTROL POINT (HACCP) SYSTEMS § 417.6 Inadequate HACCP Systems. A HACCP system may be...

Opposing and following responses in sensorimotor speech control: Why responses go both ways.

PubMed

Franken, Matthias K; Acheson, Daniel J; McQueen, James M; Hagoort, Peter; Eisner, Frank

2018-06-04

When talking, speakers continuously monitor and use the auditory feedback of their own voice to control and inform speech production processes. When speakers are provided with auditory feedback that is perturbed in real time, most of them compensate for this by opposing the feedback perturbation. But some responses follow the perturbation. In the present study, we investigated whether the state of the speech production system at perturbation onset may determine what type of response (opposing or following) is made. The results suggest that whether a perturbation-related response is opposing or following depends on ongoing fluctuations of the production system: The system initially responds by doing the opposite of what it was doing. This effect and the nontrivial proportion of following responses suggest that current production models are inadequate: They need to account for why responses to unexpected sensory feedback depend on the production system's state at the time of perturbation.

Development and testing of the Rho Sigma Incorporated microprocessor control subsystem

NASA Technical Reports Server (NTRS)

Hankins, J. D.

1979-01-01

Product development and performance tests of three programmable microprocessor controllers for use with solar heating and cooling systems are presented. The products were developed to be marketable for public use.

[Update on microbiological quality assurance meat and meat products in Morocco].

PubMed

Rachidi, H; Latrache, H

2018-03-01

Food safety has become an absolute necessity in all countries. As a result, Morocco has taken several measures and actions to develop food safety and food-borne disease control. This study aimed to highlight the level of improvement in the quality assurance of meat and meat products in Morocco. It is based on a non-exhaustive review of the regulatory texts governing food safety in the country, as well as a statistical study on establishments of meat and meat products adopting a self-checking system and approved by the National Office of Sanitary Safety of Food. Morocco has introduced several laws and regulations requiring sanitary control of food products. Also, the number of establishments of meat and meat products adopting a system of self-control and approved by the National Office of Sanitary Safety of Food has improved significantly. It has increased from 58 in 2007 to 273 in 2016. The adoption of self-monitoring systems allows better access to international markets, improved quality of food products and a considerable reduction in microbial contamination. Copyright © 2018 Elsevier Masson SAS. All rights reserved.

How NASA KSC Controls Interfaces with the use of Motion Skeletons and Product Structure

NASA Technical Reports Server (NTRS)

Jones, Corey

2013-01-01

This presentation will show how NASA KSC controls interfaces for Modular Product Architecture (MPA) using Locator Skeletons, Interface Skeletons, and Product Structure, to be combined together within a Motion Skeleton. The user will learn how to utilize skeleton models to communicate interface data, as successfully done at NASA KSC in their use of Motion Skeletons to control interfaces for multi-launch systems. There will be discussion of the methodology used to control design requirements through WTParts, and how to utilize product structure for non-CAD documents.

Flexible data registration and automation in semiconductor production

NASA Astrophysics Data System (ADS)

Dudde, Ralf; Staudt-Fischbach, Peter; Kraemer, Benedict

1997-08-01

The need for cost reduction and flexibility in semiconductor production will result in a wider application of computer based automation systems. With the setup of a new and advanced CMOS semiconductor line in the Fraunhofer Institute for Silicon Technology [ISIT, Itzehoe (D)] a new line information system (LIS) was introduced based on an advanced model for the underlying data structure. This data model was implemented into an ORACLE-RDBMS. A cellworks based system (JOSIS) was used for the integration of the production equipment, communication and automated database bookings and information retrievals. During the ramp up of the production line this new system is used for the fab control. The data model and the cellworks based system integration is explained. This system enables an on-line overview of the work in progress in the fab, lot order history and equipment status and history. Based on this figures improved production and cost monitoring and optimization is possible. First examples of the information gained by this system are presented. The modular set-up of the LIS system will allow easy data exchange with additional software tools like scheduler, different fab control systems like PROMIS and accounting systems like SAP. Modifications necessary for the integration of PROMIS are described.

Design concept of a cryogenic distillation column cascade for a ITER scale fusion reactor

NASA Astrophysics Data System (ADS)

Yamanishi, Toshihiko; Enoeda, Mikio; Okuno, Kenji

1994-07-01

A column cascade has been proposed for the fuel cycle of a ITER scale fusion reactor. The proposed cascade consists of three columns and has significant features: either top or bottom product is prior to the other for each column; it is avoided to withdraw side streams as products or feeds of down stream columns; and there is no recycle steam between the columns. In addition, the product purity of the cascade can be maintained against the changes of flow rates and compositions of feed streams just by adjusting the top and bottom flow rates. The control system has been designed for each column in the cascade. A key component in the prior product stream was selected, and the analysis method of this key component was proposed. The designed control system never brings instability as long as the concentration of the key component is measured with negligible time lag. The time lag for the measurement considerably affects the stability of the control system. A significant conclusion by the simulation in this work is that permissible time for the measurement is about 0.5 hour to obtain stable control. Hence, the analysis system using the gas chromatography is valid for control of the columns.

Production of potato minitubers using advanced environmental control technologies developed for growing plants in space

NASA Astrophysics Data System (ADS)

Britt, Robert G.

1998-01-01

Development of plant growth systems for use in outer space have been modified for use on earth as the backbone of a new system for rapid growth of potato minitubers. The automation of this new biotechnology provides for a fully controllable method of producing pathogen-free nuclear stock potato minitubers from tissue cultured clones of varieties of potato in a biomanufacturing facility. These minitubers are the beginning stage of seed potato production. Because the new system provides for pathogen-free minitubers by the tens-of-millions, rather than by the thousands which are currently produced in advanced seed potato systems, a new-dimension in seed potato development, breeding and multiplication has been achieved. The net advantage to earth-borne agricultural farming systems will be the elimination of several years of seed multiplication from the current system, higher quality potato production, and access to new potato varieties resistant to diseases and insects which will eliminate the need for chemical controls.

Epidemiology of East Coast fever (Theileria parva infection) in Kenya: past, present and the future.

PubMed

Gachohi, John; Skilton, Rob; Hansen, Frank; Ngumi, Priscilla; Kitala, Philip

2012-09-07

In this article, we review the epidemiology of East Coast fever (ECF), a tick-borne infection of cattle, in Kenya. The major factors associated with epidemiology of ECF include the agro-ecological zone (AEZ), livestock production system (LPS) and both animal breed and age. These factors appear to influence the epidemiology of ECF through structured gradients. We further show that the gradients are dynamically shaped by socio-demographic and environmental processes. For a vector-borne disease whose transmission depends on environmental characteristics that influence vector dynamics, a change in the environment implies a change in the epidemiology of the disease. The review recommends that future ECF epidemiological studies should account for these factors and the dynamic interactions between them. In Kenya, ECF control has previously relied predominantly on tick control using acaricides and chemotherapy while ECF immunization is steadily being disseminated. We highlight the contribution of ECF epidemiology and economics in the design of production system and/or geographical area-specific integrated control strategies based on both the dynamic epidemiological risk of the disease and economic impacts of control strategies. In all production systems (except marginal areas), economic analyses demonstrate that integrated control in which ECF immunization is always an important component, can play an important role in the overall control of the disease. Indeed, Kenya has recently approved ECF immunization in all production systems (except in marginal areas). If the infrastructure of the vaccine production and distribution can be heightened, large ECF endemic areas are expected to be endemically stable and the disease controlled. Finally, the review points the way for future research by identifying scenario analyses as a critical methodology on which to base future investigations on how both dynamic livestock management systems and patterns of land use influence the dynamics and complexity of ECF epidemiology and the implications for control.

Epidemiology of East Coast fever (Theileria parva infection) in Kenya: past, present and the future

PubMed Central

2012-01-01

In this article, we review the epidemiology of East Coast fever (ECF), a tick-borne infection of cattle, in Kenya. The major factors associated with epidemiology of ECF include the agro-ecological zone (AEZ), livestock production system (LPS) and both animal breed and age. These factors appear to influence the epidemiology of ECF through structured gradients. We further show that the gradients are dynamically shaped by socio-demographic and environmental processes. For a vector-borne disease whose transmission depends on environmental characteristics that influence vector dynamics, a change in the environment implies a change in the epidemiology of the disease. The review recommends that future ECF epidemiological studies should account for these factors and the dynamic interactions between them. In Kenya, ECF control has previously relied predominantly on tick control using acaricides and chemotherapy while ECF immunization is steadily being disseminated. We highlight the contribution of ECF epidemiology and economics in the design of production system and/or geographical area-specific integrated control strategies based on both the dynamic epidemiological risk of the disease and economic impacts of control strategies. In all production systems (except marginal areas), economic analyses demonstrate that integrated control in which ECF immunization is always an important component, can play an important role in the overall control of the disease. Indeed, Kenya has recently approved ECF immunization in all production systems (except in marginal areas). If the infrastructure of the vaccine production and distribution can be heightened, large ECF endemic areas are expected to be endemically stable and the disease controlled. Finally, the review points the way for future research by identifying scenario analyses as a critical methodology on which to base future investigations on how both dynamic livestock management systems and patterns of land use influence the dynamics and complexity of ECF epidemiology and the implications for control. PMID:22958352

Shallow peatland ecohydrology - the control of peat depth on moss productivity

NASA Astrophysics Data System (ADS)

Dixon, Simon; Kettridge, Nicholas; Moore, Paul; Devito, Kevin; Tilak, Amey; Petrone, Rich; Mendoza, Carl; Waddington, Mike

2017-04-01

Northern peatlands represent an important sink in the global carbon cycle. Shallow peatlands and marginal connective wetlands can be essential components of many northern peatland landscape mosaics, playing a vital role in landscape connectivity and wider landscape hydrology. However the ecohydrological function of these shallow, marginal systems has been largely overlooked, with peatland hydrology research focused on relatively deep bog systems. In order to predict landscape scale wetland function and its vulnerability to climate change we need to understand how these shallow connective systems function. The balance between moss productivity and water loss provide a key component of these systems, as water use efficiency controls the rate of moss growth and thus controls the amount of atmospheric carbon sequestered in peat. Understanding how productivity of shallow peatland systems responds to changes in evaporative stress will aid predictions of peatland landscape hydrological function in a changing climate. To determine the factors influencing peat productivity, water balance simulations using Hydrus 1-D were conducted over annual growing seasons for different soil profile depths, compositions and antecedent moisture conditions. Our results demonstrate a bimodal distribution of peatland responses; either primarily conserving water by limiting evapotranspiration or, maximizing productivity. For sustained periods of evaporative stress, shallow marginal systems are least able to buffer periods of evaporative stress due to limited labile water storage, and will limit evaporation, conserve water and be less productive. Conversely, where present, both deep water storage and a shallow initial water table prolong the onset of high vegetative stress, thus maximizing moss productivity. However, a total depth of 0.8 m is identified as the threshold above which increasing peat depth has no further effect on changing vegetative stress response and thus landscape function. These results are important as moss productivity, along with rate of organic matter decay are the two principle factors controlling the build-up of peat, and therefore sequestration of carbon. With a predicted increase in the frequency and size of rain events in northern latitudes our results indicate the productivity of shallow wetland systems may increase, but greater moisture availability will increase the likelihood they remain as wetlands in a changing climate.

PLANT - An experimental task for the study of human problem solving in process control. [Production Levels and Network Troubleshooting

NASA Technical Reports Server (NTRS)

Morris, N. M.; Rouse, W. B.; Fath, J. L.

1985-01-01

An experimental tool for the investigation of human problem-solving behavior is introduced. Production Levels and Network Troubleshooting (PLANT) is a computer-based process-control task which may be used to provide opportunities for subjects to control a dynamic system and diagnose, repair, and compensate for system failures. The task is described in detail, and experiments which have been conducted using PLANT are briefly discussed.

An Improved Formulation of Hybrid Model Predictive Control With Application to Production-Inventory Systems.

PubMed

Nandola, Naresh N; Rivera, Daniel E

2013-01-01

We consider an improved model predictive control (MPC) formulation for linear hybrid systems described by mixed logical dynamical (MLD) models. The algorithm relies on a multiple-degree-of-freedom parametrization that enables the user to adjust the speed of setpoint tracking, measured disturbance rejection and unmeasured disturbance rejection independently in the closed-loop system. Consequently, controller tuning is more flexible and intuitive than relying on objective function weights (such as move suppression) traditionally used in MPC schemes. The controller formulation is motivated by the needs of non-traditional control applications that are suitably described by hybrid production-inventory systems. Two applications are considered in this paper: adaptive, time-varying interventions in behavioral health, and inventory management in supply chains under conditions of limited capacity. In the adaptive intervention application, a hypothetical intervention inspired by the Fast Track program, a real-life preventive intervention for reducing conduct disorder in at-risk children, is examined. In the inventory management application, the ability of the algorithm to judiciously alter production capacity under conditions of varying demand is presented. These case studies demonstrate that MPC for hybrid systems can be tuned for desired performance under demanding conditions involving noise and uncertainty.

An Improved Formulation of Hybrid Model Predictive Control With Application to Production-Inventory Systems

PubMed Central

Nandola, Naresh N.; Rivera, Daniel E.

2013-01-01

We consider an improved model predictive control (MPC) formulation for linear hybrid systems described by mixed logical dynamical (MLD) models. The algorithm relies on a multiple-degree-of-freedom parametrization that enables the user to adjust the speed of setpoint tracking, measured disturbance rejection and unmeasured disturbance rejection independently in the closed-loop system. Consequently, controller tuning is more flexible and intuitive than relying on objective function weights (such as move suppression) traditionally used in MPC schemes. The controller formulation is motivated by the needs of non-traditional control applications that are suitably described by hybrid production-inventory systems. Two applications are considered in this paper: adaptive, time-varying interventions in behavioral health, and inventory management in supply chains under conditions of limited capacity. In the adaptive intervention application, a hypothetical intervention inspired by the Fast Track program, a real-life preventive intervention for reducing conduct disorder in at-risk children, is examined. In the inventory management application, the ability of the algorithm to judiciously alter production capacity under conditions of varying demand is presented. These case studies demonstrate that MPC for hybrid systems can be tuned for desired performance under demanding conditions involving noise and uncertainty. PMID:24348004

Focus control enhancement and on-product focus response analysis methodology

NASA Astrophysics Data System (ADS)

Kim, Young Ki; Chen, Yen-Jen; Hao, Xueli; Samudrala, Pavan; Gomez, Juan-Manuel; Mahoney, Mark O.; Kamalizadeh, Ferhad; Hanson, Justin K.; Lee, Shawn; Tian, Ye

2016-03-01

With decreasing CDOF (Critical Depth Of Focus) for 20/14nm technology and beyond, focus errors are becoming increasingly critical for on-product performance. Current on product focus control techniques in high volume manufacturing are limited; It is difficult to define measurable focus error and optimize focus response on product with existing methods due to lack of credible focus measurement methodologies. Next to developments in imaging and focus control capability of scanners and general tool stability maintenance, on-product focus control improvements are also required to meet on-product imaging specifications. In this paper, we discuss focus monitoring, wafer (edge) fingerprint correction and on-product focus budget analysis through diffraction based focus (DBF) measurement methodology. Several examples will be presented showing better focus response and control on product wafers. Also, a method will be discussed for a focus interlock automation system on product for a high volume manufacturing (HVM) environment.

Initial Flight Test of the Production Support Flight Control Computers at NASA Dryden Flight Research Center

NASA Technical Reports Server (NTRS)

Carter, John; Stephenson, Mark

1999-01-01

The NASA Dryden Flight Research Center has completed the initial flight test of a modified set of F/A-18 flight control computers that gives the aircraft a research control law capability. The production support flight control computers (PSFCC) provide an increased capability for flight research in the control law, handling qualities, and flight systems areas. The PSFCC feature a research flight control processor that is "piggybacked" onto the baseline F/A-18 flight control system. This research processor allows for pilot selection of research control law operation in flight. To validate flight operation, a replication of a standard F/A-18 control law was programmed into the research processor and flight-tested over a limited envelope. This paper provides a brief description of the system, summarizes the initial flight test of the PSFCC, and describes future experiments for the PSFCC.

78 FR 31431 - Export Administration Regulations (EAR): Control of Spacecraft Systems and Related Items the...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-24

.... Paragraph 9A515.b would control ground control systems and training simulators ``specially designed'' for.... Paragraph .d would control certain radiation hardened microelectronic circuits that are ``specially designed... .a would control test, inspection, and production ``equipment'' ``specially designed'' for the...

Dynamic control of photosynthetic photon flux for lettuce production in CELSS

NASA Technical Reports Server (NTRS)

Chun, C.; Mitchell, C. A.

1996-01-01

A new dynamic control of photosynthetic photon flux (PPF) was tested using lettuce canopies growing in the Minitron II plant-growth/canopy gas-exchange system. Canopy photosynthetic rates (Pn) were measured in real time and fedback for further environment control. Pn can be manipulated by changing PPF, which is a good environmental parameter for dynamic control of crop production in a Controlled Ecological Life-Support Systems CELSS. Decision making that combines empirical mathematical models with rule sets developed from recent experimental data was tested. With comparable yield indices and potential for energy savings, dynamic control strategies will contribute greatly to the sustainability of space-deployed CELSS.

Rapid Prototyping of Slot Die Devices for Roll to Roll Production of EL Fibers

PubMed Central

Bellingham, Alyssa; Bromhead, Nicholas; Fontecchio, Adam

2017-01-01

There is a growing interest in fibers supporting optoelectrical properties for textile and wearable display applications. Solution-processed electroluminescent (EL) material systems can be continuously deposited onto fiber or yarn substrates in a roll-to-roll process, making it easy to scale manufacturing. It is important to have precise control over layer deposition to achieve uniform and reliable light emission from these EL fibers. Slot-die coating offers this control and increases the rate of EL fiber production. Here, we report a highly adaptable, cost-effective 3D printing model for developing slot dies used in automatic coating systems. The resulting slot-die coating system enables rapid, reliable production of alternating current powder-based EL (ACPEL) fibers and can be adapted for many material systems. The benefits of this system over dip-coating for roll-to-roll production of EL fibers are demonstrated in this work. PMID:28772954

Rapid Prototyping of Slot Die Devices for Roll to Roll Production of EL Fibers.

PubMed

Bellingham, Alyssa; Bromhead, Nicholas; Fontecchio, Adam

2017-05-29

There is a growing interest in fibers supporting optoelectrical properties for textile and wearable display applications. Solution-processed electroluminescent (EL) material systems can be continuously deposited onto fiber or yarn substrates in a roll-to-roll process, making it easy to scale manufacturing. It is important to have precise control over layer deposition to achieve uniform and reliable light emission from these EL fibers. Slot-die coating offers this control and increases the rate of EL fiber production. Here, we report a highly adaptable, cost-effective 3D printing model for developing slot dies used in automatic coating systems. The resulting slot-die coating system enables rapid, reliable production of alternating current powder-based EL (ACPEL) fibers and can be adapted for many material systems. The benefits of this system over dip-coating for roll-to-roll production of EL fibers are demonstrated in this work.

Portable inference engine: An extended CLIPS for real-time production systems

NASA Technical Reports Server (NTRS)

Le, Thach; Homeier, Peter

1988-01-01

The present C-Language Integrated Production System (CLIPS) architecture has not been optimized to deal with the constraints of real-time production systems. Matching in CLIPS is based on the Rete Net algorithm, whose assumption of working memory stability might fail to be satisfied in a system subject to real-time dataflow. Further, the CLIPS forward-chaining control mechanism with a predefined conflict resultion strategy may not effectively focus the system's attention on situation-dependent current priorties, or appropriately address different kinds of knowledge which might appear in a given application. Portable Inference Engine (PIE) is a production system architecture based on CLIPS which attempts to create a more general tool while addressing the problems of real-time expert systems. Features of the PIE design include a modular knowledge base, a modified Rete Net algorithm, a bi-directional control strategy, and multiple user-defined conflict resolution strategies. Problems associated with real-time applications are analyzed and an explanation is given for how the PIE architecture addresses these problems.

Biological Control of Diseases of Vegetables Grown Hydroponically in Thailand: Challenge and Opportunity.

PubMed

Kanjanamaneesathian, Mana

2015-01-01

In Thailand, yield loss due to plant diseases in vegetables grown hydroponically is very high as a result of the growers` lack of knowledge for controlling diseases and their un- willingness to invest in setting-up the proper hydroponic system from the beginning. Severe root rot disease caused by Pythium spp. is frequent and can be anticipated in the hot climate in Thailand. This review focuses on the diseases in temperate lettuces which have been produced hydroponically and have been attacked by plant pathogens, particularly Pythium spp. Biological control of vegetable diseases grown hydroponically has been investigated in Thailand. Research is being carried out to identify effective strains of the antagonists, formulating the applicable products and delivering them appropriately to control the disease. Products of Bacillus subtilis, Chaetomium globosom and Trichoderma harzianum have been recommended for use to control diseases in vegetables grown hydroponically. Control efficacy of these products is varied as the biological products have been used by the growers in the paradigm of using chemical fungicide for disease control in hydroponic production system, overlooking the intrinsic characteristics of the biological control products. The recent patent, which minimizes the effects of sunlight and heat on the nutrient solution without the use of an external energy for cooling the nutrient, should be applied in producing hydroponic vegetables to mitigate poor plant growth and root rot disease outbreak in Thailand.

49 CFR 236.901 - Purpose and scope.

Code of Federal Regulations, 2010 CFR

2010-10-01

... control systems, subsystems, and components that are safety-critical products, as defined in § 236.903..., MAINTENANCE, AND REPAIR OF SIGNAL AND TRAIN CONTROL SYSTEMS, DEVICES, AND APPLIANCES Standards for Processor-Based Signal and Train Control Systems § 236.901 Purpose and scope. (a) What is the purpose of this...

ATAD control goals through the analysis of process variables and evaluation of quality, production and cost.

PubMed

Nájera, S; Gil-Martínez, M; Zambrano, J A

2015-01-01

The aim of this paper is to establish and quantify different operational goals and control strategies in autothermal thermophilic aerobic digestion (ATAD). This technology appears as an alternative to conventional sludge digestion systems. During the batch-mode reaction, high temperatures promote sludge stabilization and pasteurization. The digester temperature is usually the only online, robust, measurable variable. The average temperature can be regulated by manipulating both the air injection and the sludge retention time. An improved performance of diverse biochemical variables can be achieved through proper manipulation of these inputs. However, a better quality of treated sludge usually implies major operating costs or a lower production rate. Thus, quality, production and cost indices are defined to quantify the outcomes of the treatment. Based on these, tradeoff control strategies are proposed and illustrated through some examples. This paper's results are relevant to guide plant operators, to design automatic control systems and to compare or evaluate the control performance on ATAD systems.

Telemetry and control system for interplatform crude loading at the Statfjord Field

DOE Office of Scientific and Technical Information (OSTI.GOV)

Malmin, P.C.; Lassa, P.

1986-01-01

A control system for crude loading to tankers at the Statfjord field has been designed by Mobil Exploration Norway Inc. The objective of the interplatform crude tieline and control system was to allow tanker loading to take place at all times in order to prevent production shutdowns due to loading buoy problems. The control system has been designed to maximize the flexibility of loading operations and meet all safety and regulatory requirements. This paper discusses the design criteria for the crude tieline control system, and describes how these were met by utilizing fail safe telemetry equipment, hardwired permissive relay logicmore » and programmable logic controllers (PLC's). The experience gained from more than three years of operation of the system is reviewed. The system has allowed maximum use of total field storage capacity while loading crude to 125000 DWT tankers nearly every day throughout the year. It has been possible to maintain a high production rate event through periods of difficult weather conditions as experienced in the northern North Sea.« less

Design requirements for SRB production control system. Volume 4: Implementation

NASA Technical Reports Server (NTRS)

1981-01-01

The implementation plan which is presented was developed to provide the means for the successful implementation of the automated production control system. There are three factors which the implementation plan encompasses: detailed planning; phased implementation; and user involvement. The plan is detailed to the task level in terms of necessary activities as the system is developed, refined, installed, and tested. These tasks are scheduled, on a preliminary basis, over a two-and-one-half-year time frame.

Control by quality: proposition of a typology.

PubMed

Pujo, P; Pillet, M

The application of Quality tools and methods in industrial management has always had a fundamental impact on the control of production. It influences the behavior of the actors concerned, while introducing the necessary notions and formalizations, especially for production systems with little or no automation, which constitute a large part of the industrial activity. Several quality approaches are applied in the workshop and are implemented at the level of the control. In this paper, the authors present a typology of the various approaches that have successively influenced control, such as statistical process control, quality assurance, and continuous improvement. First the authors present a parallel between production control and quality organizational structure. They note the duality between control, which is aimed at increasing productivity, and quality, which aims to satisfy the needs of the customer. They also note the hierarchical organizational structure of these two systems of management with, at each level, the notion of a feedback loop. This notion is fundamental to any kind of decision making. The paper is organized around the operational, tactical, and strategic levels, by describing for each level the main methods and tools for control by quality. The overview of these tools and methods starts at the operational level, with the Statistical Process Control, the Taguchi technique, and the "six sigma" approach. On the tactical level, we find a quality system approach, with a documented description of the procedures introduced in the firm. The management system can refer here to Quality Assurance, Total Productive Maintenance, or Management by Total Quality. The formalization through procedures of the rules of decision governing the process control enhances the validity of these rules. This leads to the enhancement of their reliability and to their consolidation. All this counterbalances the human, intrinsically fluctuating, behavior of the control operators. Strategic control by quality is then detailed, and the two main approaches, the continuous improvement approach and the proactive improvement approach, are introduced. Finally, the authors observe that at each of the three levels, the continuous process improvement, which is a component of Total Quality, becomes an essential preoccupation for the control. Ultimately, the recursive utilization of the Deming cycle remains the best practice for the control by quality.

Investigate Methods of Improving Production Throughput in a Shipyard (The National Shipbuilding Research Program)

DTIC Science & Technology

1995-09-01

New Global Competition” ...10 “New Systems for Process Control and Product Costing ” . . . 11 “Performance Measurement Systems for the Future”, should...Selected Highlights: Page 53-World Class - Definition and applicable discussions. “Its clear that yesterdays cost systems don’t work in todays...Why conventional cost systems fail Indirect, No information about activities, Too late. Plant activities only, Inaccurate product costs , No customer

Multiple Flow Loop SCADA System Implemented on the Production Prototype Loop

DOE Office of Scientific and Technical Information (OSTI.GOV)

Baily, Scott A.; Dalmas, Dale Allen; Wheat, Robert Mitchell

2015-11-16

The following report covers FY 15 activities to develop supervisory control and data acquisition (SCADA) system for the Northstar Moly99 production prototype gas flow loop. The goal of this effort is to expand the existing system to include a second flow loop with a larger production-sized blower. Besides testing the larger blower, this system will demonstrate the scalability of our solution to multiple flow loops.

The development of daily monitoring tool in a service part manufacturing company

NASA Astrophysics Data System (ADS)

Marpaung, Seamus Tadeo; Rosyidi, Cucuk Nur

2018-02-01

Production lead time is one of the key measures to assess whether a production system is running well or not. A short lead time will lead to higher customer satisfaction and will be a solid proof that a system is well-organized. To shorten the production lead time, a good production planning and control are required. There are many obstacles which can occur at any time, for instance shortage of material and worker, or poor production scheduling. Service Parts Planning Department works with many parties from the beginning of service parts production until it is delivered to the customer. This research was conducted to find an appropriate production monitoring tool for Service Parts Planning Department, which is a control method that make problems appears to the surface and can be overcome quickly so that the production process can run normally. The tool development started with a field study to find out the production flow from start to finish, a literature review and a interview with some employees who will later use the production control tool, and the creation of a daily control that went through several modifications until finally meet the needs of the department. In this research, a production monitoring tool which is developed can be used to monitor the entire order status, the production lead time, and also serves as the records and reports for presentation.

A system framework of inter-enterprise machining quality control based on fractal theory

NASA Astrophysics Data System (ADS)

Zhao, Liping; Qin, Yongtao; Yao, Yiyong; Yan, Peng

2014-03-01

In order to meet the quality control requirement of dynamic and complicated product machining processes among enterprises, a system framework of inter-enterprise machining quality control based on fractal was proposed. In this system framework, the fractal-specific characteristic of inter-enterprise machining quality control function was analysed, and the model of inter-enterprise machining quality control was constructed by the nature of fractal structures. Furthermore, the goal-driven strategy of inter-enterprise quality control and the dynamic organisation strategy of inter-enterprise quality improvement were constructed by the characteristic analysis on this model. In addition, the architecture of inter-enterprise machining quality control based on fractal was established by means of Web service. Finally, a case study for application was presented. The result showed that the proposed method was available, and could provide guidance for quality control and support for product reliability in inter-enterprise machining processes.

[Development of whole process quality control and management system of traditional Chinese medicine decoction pieces based on traditional Chinese medicine quality tree].

PubMed

Yu, Wen-Kang; Dong, Ling; Pei, Wen-Xuan; Sun, Zhi-Rong; Dai, Jun-Dong; Wang, Yun

2017-12-01

The whole process quality control and management of traditional Chinese medicine (TCM) decoction pieces is a system engineering, involving the base environment, seeds and seedlings, harvesting, processing and other multiple steps, so the accurate identification of factors in TCM production process that may induce the quality risk, as well as reasonable quality control measures are very important. At present, the concept of quality risk is mainly concentrated in the aspects of management and regulations, etc. There is no comprehensive analysis on possible risks in the quality control process of TCM decoction pieces, or analysis summary of effective quality control schemes. A whole process quality control and management system for TCM decoction pieces based on TCM quality tree was proposed in this study. This system effectively combined the process analysis method of TCM quality tree with the quality risk management, and can help managers to make real-time decisions while realizing the whole process quality control of TCM. By providing personalized web interface, this system can realize user-oriented information feedback, and was convenient for users to predict, evaluate and control the quality of TCM. In the application process, the whole process quality control and management system of the TCM decoction pieces can identify the related quality factors such as base environment, cultivation and pieces processing, extend and modify the existing scientific workflow according to their own production conditions, and provide different enterprises with their own quality systems, to achieve the personalized service. As a new quality management model, this paper can provide reference for improving the quality of Chinese medicine production and quality standardization. Copyright© by the Chinese Pharmaceutical Association.

The remote supervisory and controlling experiment system of traditional Chinese medicine production based on Fieldbus

NASA Astrophysics Data System (ADS)

Zhan, Jinliang; Lu, Pei

2006-11-01

Since the quality of traditional Chinese medicine products are affected by raw material, machining and many other factors, it is difficult for traditional Chinese medicine production process especially the extracting process to ensure the steady and homogeneous quality. At the same time, there exist some quality control blind spots due to lacking on-line quality detection means. But if infrared spectrum analysis technology was used in traditional Chinese medicine production process on the basis of off-line analysis to real-time detect the quality of semi-manufactured goods and to be assisted by advanced automatic control technique, the steady and homogeneous quality can be obtained. It can be seen that the on-line detection of extracting process plays an important role in the development of Chinese patent medicines industry. In this paper, the design and implement of a traditional Chinese medicine extracting process monitoring experiment system which is based on PROFIBUS-DP field bus, OPC, and Internet technology is introduced. The system integrates intelligence node which gathering data, superior sub-system which achieving figure configuration and remote supervisory, during the process of traditional Chinese medicine production, monitors the temperature parameter, pressure parameter, quality parameter etc. And it can be controlled by the remote nodes in the VPN (Visual Private Network). Experiment and application do have proved that the system can reach the anticipation effect fully, and with the merits of operational stability, real-time, reliable, convenient and simple manipulation and so on.

Scheduling algorithms for automatic control systems for technological processes

NASA Astrophysics Data System (ADS)

Chernigovskiy, A. S.; Tsarev, R. Yu; Kapulin, D. V.

2017-01-01

Wide use of automatic process control systems and the usage of high-performance systems containing a number of computers (processors) give opportunities for creation of high-quality and fast production that increases competitiveness of an enterprise. Exact and fast calculations, control computation, and processing of the big data arrays - all of this requires the high level of productivity and, at the same time, minimum time of data handling and result receiving. In order to reach the best time, it is necessary not only to use computing resources optimally, but also to design and develop the software so that time gain will be maximal. For this purpose task (jobs or operations), scheduling techniques for the multi-machine/multiprocessor systems are applied. Some of basic task scheduling methods for the multi-machine process control systems are considered in this paper, their advantages and disadvantages come to light, and also some usage considerations, in case of the software for automatic process control systems developing, are made.

Application of the suggestion system in the improvement of the production process and product quality control

NASA Astrophysics Data System (ADS)

Gołaś, H.; Mazur, A.; Gruszka, J.; Szafer, P.

2016-08-01

The elaboration is a case study and the research was carried out in the company Alco-Mot Ltd., which employs 120 people. The company specializes in the production of lead poles for industrial and traction batteries using gravity casting. The elements embedded in the cast are manufactured on a machining centre, which provides the stability of the process and of the dimensions of the product as well as a very short production time. As a result of observation and analysis the authors have developed a concept for the implementation of a dynamic suggestion system in ALCO-MOT, including, among others, a standard for actions in the implementation of the suggestion system, as well as clear guidelines for the processing and presentation of the activities undertaken in the time between the establishment of the concept (suggestions) and the benefits analysis after the proposed solutions have been implemented. The authors also present how suggestions proposed by ALCO-MOT staff contributed to the improvement of the processes of production and quality control. Employees offered more than 30 suggestions, of which more than a half are being implemented now and further actions are being prepared for implementation. The authors will present the results of improvements in, for example, tool replacement time, scrap reduction. The authors will present how kaizen can improve the production and quality control processes. They will present how the production and quality control processes looked before and after the implementation of employee suggestions.

Implements and cultivation frequency to improve in-row weed control in organic peanut production

USDA-ARS?s Scientific Manuscript database

Weed control in organic peanut production is difficult and costly, which limits expansion of the production system. Sweep cultivation in the row middles is effective, but weeds remain in the crop row causing yield loss. Research trials were conducted in Tifton, GA to evaluate implements and freque...

Effects of Controlled Release Fertilizer on the Post-Production Performance of Impatiens Wallerana

USDA-ARS?s Scientific Manuscript database

Controlled release fertilizers (CRF) in production systems have been known to reduce environmental contamination. However, there is a lot to be explored as per its use in bedding plant production. Bedding plant growers have not adapted CRF use because there is little information about its use and ...

Sweat, Brain-Power, Horsepower, and Time - The Keys to Controlling Weeds

USDA-ARS?s Scientific Manuscript database

Weed control in organic crop production is difficult and costly. Early studies on organic weed control in conservation tillage systems were disappointing. Research shifted to organic weed control in conventional tillage systems. Intense cultivation with a tine weeder was the most consistent metho...

The economics of optimal health and productivity in smallholder livestock systems in developing countries.

PubMed

McDermott, J J; Randolph, T F; Staal, S J

1999-08-01

Livestock kept or produced in smallholder farming systems are an important component of the agricultural economy in the developing world. The role of livestock on smallholder farms varies widely, providing draught power for crop production or as a production activity for subsistence needs or market sale under systems ranging from extensive pastoralist to intensive, peri-urban feeder and dairy systems. A set of unique conditions and features characterise smallholder systems, and these need to be appreciated when assessing the strategies that have evolved for managing animal health in smallholder systems, and evaluating opportunities for improving disease control strategies. To provide a framework for discussing animal health issues and analytical methodogies, a typology of smallholder livestock and crop/livestock systems is developed. The typology considers livestock systems both in terms of the degree of intensification, as measured by market orientation and intensity of factor use, and in terms of importance within the household economy, as measured by contribution to household income. A number of characteristics are identified that distinguish smallholder systems from the commercialised systems of developed countries, including the multiple functions livestock serve, the integrated nature of livestock activities, multiple objectives of producers and lower capacity to bear risk at the household level, as well as poor infrastructure, markets, and access to information at the community level. Three representative smallholder livestock systems from Africa are described in detail, highlighting the relevant characteristics and the implications for analysing disease control strategies. Smallholder dairy systems in Kenya demonstrate the role of individual producer decision-making for animal health management in intensive, market-oriented systems, placing emphasis on farm-level risk and production management aspects of disease control. In extensive pastoralist systems where epidemic disease are still important and infrastructure is poor, disease control primarily involves managing communal natural resources, requiring a different analytical approach. Finally, in crop farming systems using draught cattle, the livestock activity is an integrated component of crop production and this must be reflected in the approach used to evaluate draught animal health management. Continued development of analytical approaches and decision-support tools for disease control strategies adapted to the special characteristics of these systems will be needed as smallholder systems continue to intensify in areas with good market access, and those in marginal areas face increasing pressures to optimally manage the natural resource base.

Stochastic state-space temperature regulation of biochar production. Part I: Theoretical development.

PubMed

Cantrell, Keri B; Martin, Jerry H

2012-02-01

The concept of a designer biochar that targets the improvement of a specific soil property imposes the need for production processes to generate biochars with both high consistency and quality. These important production parameters can be affected by variations in process temperature that must be taken into account when controlling the pyrolysis of agricultural residues such as manures and other feedstocks. A novel stochastic state-space temperature regulator was developed to accurately match biochar batch production to a defined temperature input schedule. This was accomplished by describing the system's state-space with five temperature variables--four directly measured and one change in temperature. Relationships were derived between the observed state and the desired, controlled state. When testing the unit at two different temperatures, the actual pyrolytic temperature was within 3 °C of the control with no overshoot. This state-space regulator simultaneously controlled the indirect heat source and sample temperature by employing difficult-to-measure variables such as temperature stability in the description of the pyrolysis system's state-space. These attributes make a state-space controller an optimum control scheme for the production of a predictable, repeatable designer biochar. Published 2011 by John Wiley & Sons, Ltd.

Computer vision for foreign body detection and removal in the food industry

USDA-ARS?s Scientific Manuscript database

Computer vision inspection systems are often used for quality control, product grading, defect detection and other product evaluation issues. This chapter focuses on the use of computer vision inspection systems that detect foreign bodies and remove them from the product stream. Specifically, we wi...

A highly tunable system for the simultaneous expression of multiple enzymes in Saccharomyces cerevisiae.

PubMed

Ito, Yoichiro; Yamanishi, Mamoru; Ikeuchi, Akinori; Matsuyama, Takashi

2015-01-16

Control of the expression levels of multiple enzymes in transgenic yeasts is essential for the effective production of complex molecules through fermentation. Here, we propose a tunable strategy for the control of expression levels based on the design of terminator regions and other gene-expression control elements in Saccharomyces cerevisiae. Our genome-integrated system, which is capable of producing high expression levels over a wide dynamic range, will broadly enable metabolic engineering and synthetic biology. We demonstrated that the activities of multiple cellulases and the production of ethanol were doubled in a transgenic yeast constructed with our system compared with those achieved with a standard expression system.

Design And Implementation Of Integrated Vision-Based Robotic Workcells

NASA Astrophysics Data System (ADS)

Chen, Michael J.

1985-01-01

Reports have been sparse on large-scale, intelligent integration of complete robotic systems for automating the microelectronics industry. This paper describes the application of state-of-the-art computer-vision technology for manufacturing of miniaturized electronic components. The concepts of FMS - Flexible Manufacturing Systems, work cells, and work stations and their control hierarchy are illustrated in this paper. Several computer-controlled work cells used in the production of thin-film magnetic heads are described. These cells use vision for in-process control of head-fixture alignment and real-time inspection of production parameters. The vision sensor and other optoelectronic sensors, coupled with transport mechanisms such as steppers, x-y-z tables, and robots, have created complete sensorimotor systems. These systems greatly increase the manufacturing throughput as well as the quality of the final product. This paper uses these automated work cells as examples to exemplify the underlying design philosophy and principles in the fabrication of vision-based robotic systems.

Increasing Student Interest and Comprehension of Production Planning and Control and Operations Performance Measurement Concepts Using a Production Line Game

ERIC Educational Resources Information Center

Cox, James F., III; Walker, Edward D., II

2005-01-01

Production planning and control (PPC) systems and operations performance measures are topics that students generally find both boring and difficult to understand. In the article, the authors present a production line game that they have found to be an effective tool to increase student interest in the topics as well as student comprehension. The…

The development and testing of a fieldworthy system of improved fluid pumping device and liquid sensor for oil wells

DOE Office of Scientific and Technical Information (OSTI.GOV)

Buckman, W.G.

1991-12-31

A major expenditure to maintain oil and gas leases is the support of pumpers, those individuals who maintain the pumping systems on wells to achieve optimum production. Many leases are marginal and are in remote areas and this requires considerable driving time for the pumper. The Air Pulse Oil Pump System is designed to be an economical system for the shallow stripper wells. To improve on the economics of this system, we have designed a Remote Oil Field Monitor and Controller to enable us to acquire data from the lease to our central office at anytime and to control themore » pumping activities from the central office by using a personal computer. The advent and economics of low-power microcontrollers have made it feasible to use this type of system for numerous remote control systems. We can also adapt this economical system to monitor and control the production of gas wells and/or pump jacks.« less

DISTRIBUTED CONTROL AND DA FOR ATLAS

DOE Office of Scientific and Technical Information (OSTI.GOV)

D. SCUDDER; ET AL

1999-05-01

The control system for the Atlas pulsed power generator being built at Los Alamos National Laboratory will utilize a significant level of distributed control. Other principal design characteristics include noise immunity, modularity and use of commercial products wherever possible. The data acquisition system is tightly coordinated with the control system. Both share a common database server and a fiber-optic ethernet communications backbone.

Final Technical Report - Advanced Optical Sensors to Minimize Energy Consumption in Polymer Extrusion Processes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Susan J. Foulk

Project Objective: The objectives of this study are to develop an accurate and stable on-line sensor system to monitor color and composition on-line in polymer melts, to develop a scheme for using the output to control extruders to eliminate the energy, material and operational costs of off-specification product, and to combine or eliminate some extrusion processes. Background: Polymer extrusion processes are difficult to control because the quality achieved in the final product is complexly affected by the properties of the extruder screw, speed of extrusion, temperature, polymer composition, strength and dispersion properties of additives, and feeder system properties. Extruder systemsmore » are engineered to be highly reproducible so that when the correct settings to produce a particular product are found, that product can be reliably produced time after time. However market conditions often require changes in the final product, different products or grades may be processed in the same equipment, and feed materials vary from lot to lot. All of these changes require empirical adjustment of extruder settings to produce a product meeting specifications. Optical sensor systems that can continuously monitor the composition and color of the extruded polymer could detect process upsets, drift, blending oscillations, and changes in dispersion of additives. Development of an effective control algorithm using the output of the monitor would enable rapid corrections for changes in materials and operating conditions, thereby eliminating most of the scrap and recycle of current processing. This information could be used to identify extruder systems issues, diagnose problem sources, and suggest corrective actions in real-time to help keep extruder system settings within the optimum control region. Using these advanced optical sensor systems would give extruder operators real-time feedback from their process. They could reduce the amount of off-spec product produced and significantly reduce energy consumption. Also, because blending and dispersion of additives and components in the final product could be continuously verified, we believe that, in many cases, intermediate compounding steps could be eliminated (saving even more time and energy).« less

Production Facility SCADA Design Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dale, Gregory E.; Holloway, Michael Andrew; Baily, Scott A.

2015-03-23

The following report covers FY 14 activities to develop supervisory control and data acquisition (SCADA) system for the Northstar Moly99 production facility. The goal of this effort is to provide Northstar with a baseline system design.

48 CFR 9.104-1 - General standards.

Code of Federal Regulations, 2012 CFR

2012-10-01

... Section 9.104-1 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION ACQUISITION PLANNING... them (including, as appropriate, such elements as production control procedures, property control... necessary production, construction, and technical equipment and facilities, or the ability to obtain them...

48 CFR 9.104-1 - General standards.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Section 9.104-1 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION ACQUISITION PLANNING... them (including, as appropriate, such elements as production control procedures, property control... necessary production, construction, and technical equipment and facilities, or the ability to obtain them...

48 CFR 9.104-1 - General standards.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Section 9.104-1 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION ACQUISITION PLANNING... them (including, as appropriate, such elements as production control procedures, property control... necessary production, construction, and technical equipment and facilities, or the ability to obtain them...

Mass storage at NSA

NASA Technical Reports Server (NTRS)

Shields, Michael F.

1993-01-01

The need to manage large amounts of data on robotically controlled devices has been critical to the mission of this Agency for many years. In many respects this Agency has helped pioneer, with their industry counterparts, the development of a number of products long before these systems became commercially available. Numerous attempts have been made to field both robotically controlled tape and optical disk technology and systems to satisfy our tertiary storage needs. Custom developed products were architected, designed, and developed without vendor partners over the past two decades to field workable systems to handle our ever increasing storage requirements. Many of the attendees of this symposium are familiar with some of the older products, such as: the Braegen Automated Tape Libraries (ATL's), the IBM 3850, the Ampex TeraStore, just to name a few. In addition, we embarked on an in-house development of a shared disk input/output support processor to manage our every increasing tape storage needs. For all intents and purposes, this system was a file server by current definitions which used CDC Cyber computers as the control processors. It served us well and was just recently removed from production usage.

Real-time product attribute control to manufacture antibodies with defined N-linked glycan levels.

PubMed

Zupke, Craig; Brady, Lowell J; Slade, Peter G; Clark, Philip; Caspary, R Guy; Livingston, Brittney; Taylor, Lisa; Bigham, Kyle; Morris, Arvia E; Bailey, Robert W

2015-01-01

Pressures for cost-effective new therapies and an increased emphasis on emerging markets require technological advancements and a flexible future manufacturing network for the production of biologic medicines. The safety and efficacy of a product is crucial, and consistent product quality is an essential feature of any therapeutic manufacturing process. The active control of product quality in a typical biologic process is challenging because of measurement lags and nonlinearities present in the system. The current study uses nonlinear model predictive control to maintain a critical product quality attribute at a predetermined value during pilot scale manufacturing operations. This approach to product quality control ensures a more consistent product for patients, enables greater manufacturing efficiency, and eliminates the need for extensive process characterization by providing direct measures of critical product quality attributes for real time release of drug product. © 2015 American Institute of Chemical Engineers.

An evaluation of a micro programmable logic controller for oxygen monitoring and control in tanks of a recirculating aquaculture system

USDA-ARS?s Scientific Manuscript database

Control of dissolved gases, especially oxygen is an essential component of recirculating aquaculture systems. The use of pure oxygen in a recirculating aquaculture system creates supersaturated concentrations of dissolved oxygen and can reduce fish production costs by supporting greater fish and fee...

Real time monitoring of powder blend bulk density for coupled feed-forward/feed-back control of a continuous direct compaction tablet manufacturing process.

PubMed

Singh, Ravendra; Román-Ospino, Andrés D; Romañach, Rodolfo J; Ierapetritou, Marianthi; Ramachandran, Rohit

2015-11-10

The pharmaceutical industry is strictly regulated, where precise and accurate control of the end product quality is necessary to ensure the effectiveness of the drug products. For such control, the process and raw materials variability ideally need to be fed-forward in real time into an automatic control system so that a proactive action can be taken before it can affect the end product quality. Variations in raw material properties (e.g., particle size), feeder hopper level, amount of lubrication, milling and blending action, applied shear in different processing stages can affect the blend density significantly and thereby tablet weight, hardness and dissolution. Therefore, real time monitoring of powder bulk density variability and its incorporation into the automatic control system so that its effect can be mitigated proactively and efficiently is highly desired. However, real time monitoring of powder bulk density is still a challenging task because of different level of complexities. In this work, powder bulk density which has a significant effect on the critical quality attributes (CQA's) has been monitored in real time in a pilot-plant facility, using a NIR sensor. The sensitivity of the powder bulk density on critical process parameters (CPP's) and CQA's has been analyzed and thereby feed-forward controller has been designed. The measured signal can be used for feed-forward control so that the corrective actions on the density variations can be taken before they can influence the product quality. The coupled feed-forward/feed-back control system demonstrates improved control performance and improvements in the final product quality in the presence of process and raw material variations. Copyright © 2015 Elsevier B.V. All rights reserved.

Long-pulse production of high current negative ion beam by using actively temperature controlled plasma grid for JT-60SA negative ion source

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kojima, A.; Hanada, M.; Yoshida, M.

2015-04-08

The temperature control system of the large-size plasma grid has been developed to realize the long pulse production of high-current negative ions for JT-60SA. By using this prototype system for the JT-60SA ion source, 15 A negative ions has been sustained for 100 s for the first time, which is three times longer than that obtained in JT-60U. In this system, a high-temperature fluorinated fluid with a high boiling point of 270 degree Celsius is circulated in the cooling channels of the plasma grids (PG) where a cesium (Cs) coverage is formed to enhance the negative ion production. Because themore » PG temperature control had been applied to only 10% of the extraction area previously, the prototype PG with the full extraction area (110 cm × 45 cm) was developed to increase the negative ion current in this time. In the preliminary results of long pulse productions of high-current negative ions at a Cs conditioning phase, the negative ion production was gradually degraded in the last half of 100 s pulse where the temperature of an arc chamber wall was not saturated. From the spectroscopic measurements, it was found that the Cs flux released from the wall might affect to the negative ion production, which implied the wall temperature should be kept low to control the Cs flux to the PG for the long-pulse high-current production. The obtained results of long-pulse production and the PG temperature control method contributes the design of the ITER ion source.« less

The effect of sudden server breakdown on the performance of a disassembly line

NASA Astrophysics Data System (ADS)

Udomsawat, Gun; Gupta, Surendra M.

2005-11-01

Product and material recovery relies on the disassembly process to separate target components or materials from the end-of-life (EOL) products. Disassembly line is especially effective when products in large quantity are disassembled. Unlike an assembly line, a disassembly line is more complex and is subjected to numerous uncertainties including stochastic and multi-level arrivals of component demands, stochastic arrival times for EOL products, and process interruption due to equipment failure. These factors seriously impair the control mechanism in the disassembly line. A common production control mechanism is the traditional push system (TPS). TPS responds to the aforementioned complications by carrying substantial amounts of inventories. An alternative control mechanism is a newly developed multi-kanban pull system (MKS) that relies on dynamic routing of kanbans, which tends to minimize the system's inventories while maintaining demand serviceability. In this paper we explore the impact of sudden breakdown of server on the performance of a disassembly line. We compare the overall performances of the TPS and MKS by considering two scenarios. We present the solution procedure and results for these cases.

Increasing beef production could lower greenhouse gas emissions in Brazil if decoupled from deforestation

NASA Astrophysics Data System (ADS)

de Oliveira Silva, R.; Barioni, L. G.; Hall, J. A. J.; Folegatti Matsuura, M.; Zanett Albertini, T.; Fernandes, F. A.; Moran, D.

2016-05-01

Recent debate about agricultural greenhouse gas emissions mitigation highlights trade-offs inherent in the way we produce and consume food, with increasing scrutiny on emissions-intensive livestock products. Although most research has focused on mitigation through improved productivity, systemic interactions resulting from reduced beef production at the regional level are still unexplored. A detailed optimization model of beef production encompassing pasture degradation and recovery processes, animal and deforestation emissions, soil organic carbon (SOC) dynamics and upstream life-cycle inventory was developed and parameterized for the Brazilian Cerrado. Economic return was maximized considering two alternative scenarios: decoupled livestock-deforestation (DLD), assuming baseline deforestation rates controlled by effective policy; and coupled livestock-deforestation (CLD), where shifting beef demand alters deforestation rates. In DLD, reduced consumption actually leads to less productive beef systems, associated with higher emissions intensities and total emissions, whereas increased production leads to more efficient systems with boosted SOC stocks, reducing both per kilogram and total emissions. Under CLD, increased production leads to 60% higher emissions than in DLD. The results indicate the extent to which deforestation control contributes to sustainable intensification in Cerrado beef systems, and how alternative life-cycle analytical approaches result in significantly different emission estimates.

Modelling of Robotized Manufacturing Systems Using MultiAgent Formalism

NASA Astrophysics Data System (ADS)

Foit, K.; Gwiazda, A.; Banaś, W.

2016-08-01

The evolution of manufacturing systems has greatly accelerated due to development of sophisticated control systems. On top of determined, one way production flow the need of decision making has arisen as a result of growing product range that are manufactured simultaneously, using the same resources. On the other hand, the intelligent flow control could address the “bottleneck” problem caused by the machine failure. This sort of manufacturing systems uses advanced control algorithms that are introduced by the use of logic controllers. The complex algorithms used in the control systems requires to employ appropriate methods during the modelling process, like the agent-based one, which is the subject of this paper. The concept of an agent is derived from the object-based methodology of modelling, so it meets the requirements of representing the physical properties of the machines as well as the logical form of control systems. Each agent has a high level of autonomy and could be considered separately. The multi-agent system consists of minimum two agents that can interact and modify the environment, where they act. This may lead to the creation of self-organizing structure, what could be interesting feature during design and test of manufacturing system.

Step 1: Human System Integration Simulation and Flight Test Progress Report

NASA Technical Reports Server (NTRS)

2005-01-01

The Access 5 Human Systems Integration Work Package produced simulation and flight demonstration planning products for use throughout the program. These included: Test Objectives for Command, Control, Communications; Pilot Questionnaire for Command, Control, Communications; Air Traffic Controller Questionnaire for Command, Control, Communications; Test Objectives for Collision Avoidance; Pilot Questionnaire for Collision Avoidance; Plans for Unmanned Aircraft Systems Control Station Simulations Flight Requirements for the Airspace Operations Demonstration

Solid state control system for oil well bailer pump

DOE Office of Scientific and Technical Information (OSTI.GOV)

Senghaas, K. A.; Senghaas, P.

1985-05-14

A solid state switching controller for use with various types of oil well bailer pumps. Individually programmable steps with lockouts provide multiple mutual exclusivity between various circuit operations. A trickle charge battery system powers the control circuits. A tank overflow float protects against oil spillage. An automatic production rate adjustment circuit is provided which increases cycle time in proportion to the rate of production. The circuit includes a low power voltage detector for disabling the control circuits until the line voltage is acceptable. A three-phase power and control system with an isolation transformer for the controls avoids unreliable ground connections.more » The timers include a dividing circuit with an RC circuit. All power actuated apparatus are actuated by triac switches which are controlled by an opto driver. The bailer brake is pulse actuated for allowing the bailer to sink into crude oil without excess cable looseness.« less

Global vegetation productivity response to climatic oscillations during the satellite era.

PubMed

Gonsamo, Alemu; Chen, Jing M; Lombardozzi, Danica

2016-10-01

Climate control on global vegetation productivity patterns has intensified in response to recent global warming. Yet, the contributions of the leading internal climatic variations to global vegetation productivity are poorly understood. Here, we use 30 years of global satellite observations to study climatic variations controls on continental and global vegetation productivity patterns. El Niño-Southern Oscillation (ENSO) phases (La Niña, neutral, and El Niño years) appear to be a weaker control on global-scale vegetation productivity than previously thought, although continental-scale responses are substantial. There is also clear evidence that other non-ENSO climatic variations have a strong control on spatial patterns of vegetation productivity mainly through their influence on temperature. Among the eight leading internal climatic variations, the East Atlantic/West Russia Pattern extensively controls the ensuing year vegetation productivity of the most productive tropical and temperate forest ecosystems of the Earth's vegetated surface through directionally consistent influence on vegetation greenness. The Community Climate System Model (CCSM4) simulations do not capture the observed patterns of vegetation productivity responses to internal climatic variations. Our analyses show the ubiquitous control of climatic variations on vegetation productivity and can further guide CCSM and other Earth system models developments to represent vegetation response patterns to unforced variability. Several winter time internal climatic variation indices show strong potentials on predicting growing season vegetation productivity two to six seasons ahead which enables national governments and farmers forecast crop yield to ensure supplies of affordable food, famine early warning, and plan management options to minimize yield losses ahead of time. © 2016 John Wiley & Sons Ltd.

22 CFR 62.71 - Control and production of the electronic Form DS-2019.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Control and production of the electronic Form DS-2019. 62.71 Section 62.71 Foreign Relations DEPARTMENT OF STATE PUBLIC DIPLOMACY AND EXCHANGES EXCHANGE VISITOR PROGRAM Student and Exchange Visitor Information System (SEVIS) § 62.71 Control and...

Automation Applications in an Advanced Air Traffic Management System : Volume 4A. Automation Requirements.

DOT National Transportation Integrated Search

1974-08-01

Volume 4 describes the automation requirements. A presentation of automation requirements is made for an advanced air traffic management system in terms of controller work force, computer resources, controller productivity, system manning, failure ef...

Rethinking Import and Export Controls for Defense-Related Goods

DTIC Science & Technology

2013-05-01

restrictions were imposed on the basis of country (Trading with the Enemy Act) or product (Neutrality Act). However, in the post-war environment, a more mixed...described below. • Arms Export Control Act (AECA) of 1976—grants the President the power to control the export of defense products and services. The act...defense-related items and services. The products regulated include weapons systems (e.g., aircraft, tanks, etc.) but also include subsystems or

Lighting Control System for Premises with Display Screen Equipment

NASA Astrophysics Data System (ADS)

Kudryashov, A. V.

2017-11-01

The use of Display Screen Equipment (DSE) at enterprises allows one to increase the productivity and safety of production, minimize the number of personnel and leads to the simplification of the work of specialists, but on the other side, changes usual working conditions. If the personnel works with displays, visual fatigue develops more quickly which contributes to the emergence of nervous tension, stress and possible erroneous actions. Low interest of the lighting control system developers towards the rooms with displays is dictated by special requirements for coverage by sanitary and hygienic standards (limiting excess workplace illumination). We decided to create a combined lighting system which works considering daylight illumination and artificial light sources. The brightness adjustment of the LED lamps is carried out according to the DALI protocol, adjustment of the natural illumination by means of smart glasses. The technical requirements for a lighting control system, the structural-functional scheme and the algorithm for controlling the operation of the system have been developed. The elements of control units, sensors and actuators have been selected.

On-Board Hydrogen Gas Production System For Stirling Engines

DOEpatents

Johansson, Lennart N.

2004-06-29

A hydrogen production system for use in connection with Stirling engines. The production system generates hydrogen working gas and periodically supplies it to the Stirling engine as its working fluid in instances where loss of such working fluid occurs through usage through operation of the associated Stirling engine. The hydrogen gas may be generated by various techniques including electrolysis and stored by various means including the use of a metal hydride absorbing material. By controlling the temperature of the absorbing material, the stored hydrogen gas may be provided to the Stirling engine as needed. A hydrogen production system for use in connection with Stirling engines. The production system generates hydrogen working gas and periodically supplies it to the Stirling engine as its working fluid in instances where loss of such working fluid occurs through usage through operation of the associated Stirling engine. The hydrogen gas may be generated by various techniques including electrolysis and stored by various means including the use of a metal hydride absorbing material. By controlling the temperature of the absorbing material, the stored hydrogen gas may be provided to the Stirling engine as needed.

242A Distributed Control System Year 2000 Acceptance Test Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

TEATS, M.C.

1999-08-31

This report documents acceptance test results for the 242-A Evaporator distributive control system upgrade to D/3 version 9.0-2 for year 2000 compliance. This report documents the test results obtained by acceptance testing as directed by procedure HNF-2695. This verification procedure will document the initial testing and evaluation of the potential 242-A Distributed Control System (DCS) operating difficulties across the year 2000 boundary and the calendar adjustments needed for the leap year. Baseline system performance data will be recorded using current, as-is operating system software. Data will also be collected for operating system software that has been modified to correct yearmore » 2000 problems. This verification procedure is intended to be generic such that it may be performed on any D/3{trademark} (GSE Process Solutions, Inc.) distributed control system that runs with the VMSTM (Digital Equipment Corporation) operating system. This test may be run on simulation or production systems depending upon facility status. On production systems, DCS outages will occur nine times throughout performance of the test. These outages are expected to last about 10 minutes each.« less

Telemetry and control system for interplatform crude loading at the Statfjord field

DOE Office of Scientific and Technical Information (OSTI.GOV)

Malmin, P.C.; Lassa, P.

1988-04-01

A control system for crude loading to tankers at Statfjord field has been designed to allow tanker loading to the place at all times to prevent production shutdowns caused by loading-buoy problems. This paper discusses how the control system was designed to maximize the flexibility of loading operations and to meet all safety and regulatory requirements. The experience gained from more than 4 years of operation of the system is reviewed. The system has allowed maximum use of total field crude oil storage capacity while loading to 125,000-DWT (127 000-Mg) tankers nearly every day throughout the year. It has beenmore » possible to maintain a high production rate even through the periods of difficult weather conditions experienced in the northern North Sea.« less

Fuzzy logic controller versus classical logic controller for residential hybrid solar-wind-storage energy system

NASA Astrophysics Data System (ADS)

Derrouazin, A.; Aillerie, M.; Mekkakia-Maaza, N.; Charles, J. P.

2016-07-01

Several researches for management of diverse hybrid energy systems and many techniques have been proposed for robustness, savings and environmental purpose. In this work we aim to make a comparative study between two supervision and control techniques: fuzzy and classic logics to manage the hybrid energy system applied for typical housing fed by solar and wind power, with rack of batteries for storage. The system is assisted by the electric grid during energy drop moments. A hydrogen production device is integrated into the system to retrieve surplus energy production from renewable sources for the household purposes, intending the maximum exploitation of these sources over years. The models have been achieved and generated signals for electronic switches command of proposed both techniques are presented and discussed in this paper.

Automation Applications in an Advanced Air Traffic Management System : Volume 4B. Automation Requirements (Concluded)

DOT National Transportation Integrated Search

1974-08-01

Volume 4 describes the automation requirements. A presentation of automation requirements is made for an advanced air traffic management system in terms of controller work for-e, computer resources, controller productivity, system manning, failure ef...

Central nervous system control of the laryngeal muscles in humans

PubMed Central

Ludlow, Christy L.

2005-01-01

Laryngeal muscle control may vary for different functions such as: voice for speech communication, emotional expression during laughter and cry, breathing, swallowing, and cough. This review discusses the control of the human laryngeal muscles for some of these different functions. Sensori-motor aspects of laryngeal control have been studied by eliciting various laryngeal reflexes. The role of audition in learning and monitoring ongoing voice production for speech is well known; while the role of somatosensory feedback is less well understood. Reflexive control systems involving central pattern generators may contribute to swallowing, breathing and cough with greater cortical control during volitional tasks such as voice production for speech. Volitional control is much less well understood for each of these functions and likely involves the integration of cortical and subcortical circuits. The new frontier is the study of the central control of the laryngeal musculature for voice, swallowing and breathing and how volitional and reflexive control systems may interact in humans. PMID:15927543

Scaling-up vaccine production: implementation aspects of a biomass growth observer and controller.

PubMed

Soons, Zita I T A; van den IJssel, Jan; van der Pol, Leo A; van Straten, Gerrit; van Boxtel, Anton J B

2009-04-01

This study considers two aspects of the implementation of a biomass growth observer and specific growth rate controller in scale-up from small- to pilot-scale bioreactors towards a feasible bulk production process for whole-cell vaccine against whooping cough. The first is the calculation of the oxygen uptake rate, the starting point for online monitoring and control of biomass growth, taking into account the dynamics in the gas-phase. Mixing effects and delays are caused by amongst others the headspace and tubing to the analyzer. These gas phase dynamics are modelled using knowledge of the system in order to reconstruct oxygen consumption. The second aspect is to evaluate performance of the monitoring and control system with the required modifications of the oxygen consumption calculation on pilot-scale. In pilot-scale fed-batch cultivation good monitoring and control performance is obtained enabling a doubled concentration of bulk vaccine compared to standard batch production.

New approach to control the methanogenic reactor of a two-phase anaerobic digestion system.

PubMed

von Sachs, Jürgen; Meyer, Ulrich; Rys, Paul; Feitkenhauer, Heiko

2003-03-01

A new control strategy for the methanogenic reactor of a two-phase anaerobic digestion system has been developed and successfully tested on the laboratory scale. The control strategy serves the purpose to detect inhibitory effects and to achieve good conversion. The concept is based on the idea that volatile fatty acids (VFA) can be measured in the influent of the methanogenic reactor by means of titration. Thus, information on the output (methane production) and input of the methanogenic reactor is available, and a (carbon) mass balance can be obtained. The control algorithm comprises a proportional/integral structure with the ratio of (a) the methane production rate measured online and (b) a maximum methane production rate expected (derived from the stoichiometry) as a control variable. The manipulated variable is the volumetric feed rate. Results are shown for an experiment with VFA (feed) concentration ramps and for experiments with sodium chloride as inhibitor.

Precise control of lycopene production to enable a fast-responding, minimal-equipment biosensor.

PubMed

McNerney, Monica P; Styczynski, Mark P

2017-09-01

Pigmented metabolites have great potential for use in biosensors that target low-resource areas, since sensor output can be interpreted without any equipment. However, full repression of pigment production when undesired is challenging, as even small amounts of enzyme can catalyze the production of large, visible amounts of pigment. The red pigment lycopene could be particularly useful because of its position in the multi-pigment carotenoid pathway, but commonly used inducible promoter systems cannot repress lycopene production. In this paper, we designed a system that could fully repress lycopene production in the absence of an inducer and produce visible lycopene within two hours of induction. We engineered Lac, Ara, and T7 systems to be up to 10 times more repressible, but these improved systems could still not fully repress lycopene. Translational modifications proved much more effective in controlling lycopene. By decreasing the strength of the ribosomal binding sites on the crtEBI genes, we enabled full repression of lycopene and production of visible lycopene in 3-4h of induction. Finally, we added the mevalonate pathway enzymes to increase the rate of lycopene production upon induction and demonstrated that supplementation of metabolic precursors could decrease the time to coloration to about 1.5h. In total, this represents over an order of magnitude reduction in response time compared to the previously reported strategy. The approaches used here demonstrate the disconnect between fluorescent and metabolite reporters, help enable the use of lycopene as a reporter, and are likely generalizable to other systems that require precise control of metabolite production. Copyright © 2017 International Metabolic Engineering Society. Published by Elsevier Inc. All rights reserved.

9 CFR 318.309 - Finished product inspection.

Code of Federal Regulations, 2010 CFR

2010-01-01

... microbiological contamination; (2) An FSIS-approved total quality control system; (3) Alternative documented... associated with microbial contamination, where there is no approved total quality control system, or where... Office of Management and Budget under control number 0583-0015) [51 FR 45619, Dec. 19, 1986, as amended...

Epidemiology and quality assurance: applications at farm level.

PubMed

Noordhuizen, J P; Frankena, K

1999-03-29

Animal production is relevant with respect to farm income and the position of the sector in the market, but also with respect to the quality and safety of products of animal origin, related to public health. Animal production is part of a chain of food production. Therefore, producers have to take consumer expectations and demands in the domains of animal health, welfare and environment into account. A different attitude for production has to be adopted; this attitude can be visualized in good farming practice, GFP, codes. Farmers who focused on quality in its broadest sense need a system supporting them in their management and control of quality risks. Generally speaking, there are three systems for that purpose: GFP, ISO and HACCP. When the hypothesis followed relates to animal health being a feature of quality, or else welfare and environmental issues, then animal health care can be executed following quality control principles. The HACCP concept is well suited for quality control at farm level, involving risk identification and risk management. The on-farm monitoring and surveillance system of critical control points in the animal production process is the most important tool in this procedure. Principles for HACCP application as well as certification fitness of HACCP are elaborated upon. They are illustrated by using salmonellosis in meat-pig farms as objective for an HACCP approach. It is further discussed that, in addition to animal health and quality, animal welfare and environmental issues could also be covered by an HACCP-like system in an integrated manner. Ultimately, the HACCP modules could end up in an overall ISO certification.

Improved GMP-compliant multi-dose production and quality control of 6-[18F]fluoro-L-DOPA.

PubMed

Luurtsema, G; Boersma, H H; Schepers, M; de Vries, A M T; Maas, B; Zijlma, R; de Vries, E F J; Elsinga, P H

2017-01-01

6-[ 18 F]Fluoro-L-3,4-dihydroxyphenylalanine (FDOPA) is a frequently used radiopharmaceutical for detecting neuroendocrine and brain tumors and for the differential diagnosis of Parkinson's disease. To meet the demand for FDOPA, a high-yield GMP-compliant production method is required. Therefore, this study aimed to improve the FDOPA production and quality control procedures to enable distribution of the radiopharmaceutical over distances.FDOPA was prepared by electrophilic fluorination of the trimethylstannyl precursor with [ 18 F]F 2 , produced from [ 18 O] 2 via the double-shoot approach, leading to FDOPA with higher specific activity as compared to FDOPA which was synthesized, using [ 18 F]F 2 produced from 20 Ne, leading to FDOPA with a lower specific activity. The quality control of the product was performed using a validated UPLC system and compared with quality control with a conventional HPLC system. Impurities were identified using UPLC-MS. The [ 18 O] 2 double-shoot radionuclide production method yielded significantly more [ 18 F]F 2 with less carrier F 2 than the conventional method starting from 20 Ne. After adjustment of radiolabeling parameters substantially higher amounts of FDOPA with higher specific activity could be obtained. Quality control by UPLC was much faster and detected more side-products than HPLC. UPLC-MS showed that the most important side-product was FDOPA-quinone, rather than 6-hydroxydopa as suggested by the European Pharmacopoeia. The production and quality control of FDOPA were significantly improved by introducing the [ 18 O] 2 double-shoot radionuclide production method, and product analysis by UPLC, respectively. As a result, FDOPA is now routinely available for clinical practice and for distribution over distances.

Modeling and simulation of enzymatic gluconic acid production using immobilized enzyme and CSTR-PFTR circulation reaction system.

PubMed

Li, Can; Lin, Jianqun; Gao, Ling; Lin, Huibin; Lin, Jianqiang

2018-04-01

Production of gluconic acid by using immobilized enzyme and continuous stirred tank reactor-plug flow tubular reactor (CSTR-PFTR) circulation reaction system. A production system is constructed for gluconic acid production, which consists of a continuous stirred tank reactor (CSTR) for pH control and liquid storage and a plug flow tubular reactor (PFTR) filled with immobilized glucose oxidase (GOD) for gluconic acid production. Mathematical model is developed for this production system and simulation is made for the enzymatic reaction process. The pH inhibition effect on GOD is modeled by using a bell-type curve. Gluconic acid can be efficiently produced by using the reaction system and the mathematical model developed for this system can simulate and predict the process well.

Algorithm for decision support as the tool for control system of industries with variable assortment of products

NASA Astrophysics Data System (ADS)

Ladaniuk, Anatolii; Ivashchuk, Viacheslav; Kisała, Piotr; Askarova, Nursanat; Sagymbekova, Azhar

2015-12-01

Conditions of diversification of enterprise products are involving for changes of higher levels of management hierarchy, so it's leading by tasks correcting and changing schedule for operating of production plans. Ordinary solve by combination of enterprise resource are planning and management execution system often has exclusively statistical content. So, the development of decision support system, that helps to use knowledge about subject for capabilities estimating and order of operation of production object is relevant in this time.

Review of nuclear pharmacy practice in hospitals

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kawada, T.K.; Tubis, M.; Ebenkamp, T.

1982-02-01

An operational profile for nuclear pharmacy practice is presented, and the technical and professional role of nuclear pharmacists is reviewed. Key aspects of nuclear pharmacy practice in hospitals discussed are the basic facilities and equipment for the preparation, quality control, and distribution of radioactive drug products. Standards for receiving, storing, and processing radioactive material are described. The elements of a radiopharmaceutical quality assurance program, including the working procedures, documentation systems, data analysis, and specific control tests, are presented. Details of dose preparation and administration and systems of inventory control for radioactive products are outlined.

Production planning, production systems for flexible automation

NASA Astrophysics Data System (ADS)

Spur, G.; Mertins, K.

1982-09-01

Trends in flexible manufacturing system (FMS) applications are reviewed. Machining systems contain machines which complement each other and can replace each other. Computer controlled storage systems are widespread, with central storage capacity ranging from 20 pallet spaces to 200 magazine spaces. Handling function is fulfilled by pallet chargers in over 75% of FMS's. Data system degree of automation varies considerably. No trends are noted for transport systems.

Application of Hazard Analysis and Critical Control Points (HACCP) to the Cultivation Line of Mushroom and Other Cultivated Edible Fungi.

PubMed

Pardo, José E; de Figueirêdo, Vinícius Reis; Alvarez-Ortí, Manuel; Zied, Diego C; Peñaranda, Jesús A; Dias, Eustáquio Souza; Pardo-Giménez, Arturo

2013-09-01

The Hazard analysis and critical control points (HACCP) is a preventive system which seeks to ensure food safety and security. It allows product protection and correction of errors, improves the costs derived from quality defects and reduces the final overcontrol. In this paper, the system is applied to the line of cultivation of mushrooms and other edible cultivated fungi. From all stages of the process, only the reception of covering materials (stage 1) and compost (stage 3), the pre-fruiting and induction (step 6) and the harvest (stage 7) have been considered as critical control point (CCP). The main hazards found were the presence of unauthorized phytosanitary products or above the permitted dose (stages 6 and 7), and the presence of pathogenic bacteria (stages 1 and 3) and/or heavy metals (stage 3). The implementation of this knowledge will allow the self-control of their productions based on the system HACCP to any plant dedicated to mushroom or other edible fungi cultivation.

Taming instabilities in power grid networks by decentralized control

NASA Astrophysics Data System (ADS)

Schäfer, B.; Grabow, C.; Auer, S.; Kurths, J.; Witthaut, D.; Timme, M.

2016-05-01

Renewables will soon dominate energy production in our electric power system. And yet, how to integrate renewable energy into the grid and the market is still a subject of major debate. Decentral Smart Grid Control (DSGC) was recently proposed as a robust and decentralized approach to balance supply and demand and to guarantee a grid operation that is both economically and dynamically feasible. Here, we analyze the impact of network topology by assessing the stability of essential network motifs using both linear stability analysis and basin volume for delay systems. Our results indicate that if frequency measurements are averaged over sufficiently large time intervals, DSGC enhances the stability of extended power grid systems. We further investigate whether DSGC supports centralized and/or decentralized power production and find it to be applicable to both. However, our results on cycle-like systems suggest that DSGC favors systems with decentralized production. Here, lower line capacities and lower averaging times are required compared to those with centralized production.

Quality Control Circles: A Vehicle for Just-in-Time Implementation.

ERIC Educational Resources Information Center

Sepehri, Mehran

1985-01-01

Explains just-in-time (JIT) material flow and production, a method of production designed to eliminate waste. Discusses why quality control circles work so well with a JIT system, and describes how several companies have made JIT work for them. (CT)

Research and Design on a Product Data Definition System of Semiconductor Packaging Industry

NASA Astrophysics Data System (ADS)

Shi, Jinfei; Ma, Qingyao; Zhou, Yifan; Chen, Ruwen

2017-12-01

This paper develops a product data definition (PDD) system for a semiconductor packaging and testing company with independent intellectual property rights. The new PDD system can solve the problems such as, the effective control of production plans, the timely feedback of production processes, and the efficient schedule of resources. Firstly, this paper introduces the general requirements of the PDD system and depicts the operation flow and the data flow of the PDD system. Secondly, the overall design scheme of the PDD system is put forward. After that, the physical data model is developed using the Power Designer15.0 tool, and the database system is built. Finally, the function realization and running effects of the PDD system are analysed. The successful operation of the PDD system can realize the information flow among various production departments of the enterprise to meet the standard of the enterprise manufacturing integration and improve the efficiency of production management.

Design and performance of the KSC Biomass Production Chamber

NASA Technical Reports Server (NTRS)

Prince, Ralph P.; Knott, William M.; Sager, John C.; Hilding, Suzanne E.

1987-01-01

NASA's Controlled Ecological Life Support System program has instituted the Kennedy Space Center 'breadboard' project of which the Biomass Production Chamber (BPC) presently discussed is a part. The BPC is based on a modified hypobaric test vessel; its design parameters and operational parameters have been chosen in order to meet a wide range of plant-growing objectives aboard future spacecraft on long-duration missions. A control and data acquisition subsystem is used to maintain a common link between the heating, ventilation, and air conditioning system, the illumination system, the gas-circulation system, and the nutrient delivery and monitoring subsystems.

Commercialization of veterinary viral vaccines.

PubMed

Flore, P H

2004-12-01

If vaccines are to reliably prevent disease, they must be developed, produced and quality-controlled according to very strict regulations and procedures. Veterinary viral vaccine registrations are governed by different rules in different countries, but these rules all emphasize that the quality of the raw materials--the cells, eggs, animals or plants that are used in production--need to be carefully controlled. The veterinary vaccine business is also very cost-conscious. Emphasis over the last 5-10 years has therefore been to develop culture systems that minimize labor and sterility problems and thus provide for reliable and cost-effective production. Implementing these often more complex systems in a production environment takes considerable effort, first in scale-up trials and further down the line in convincing production personnel to change their familiar system for something new and possibly untried. To complete scale-up trials successfully, it is absolutely necessary to understand the biochemistry of the cells and the influence of the virus on the cells under scale-up and later production conditions. Once a viral product can be produced on a large scale, it is imperative that the quality of the end-product is controlled in an intelligent way. One needs to know whether the end-product performs in the animal as was intended during its conception in the research and development department. The development of the appropriate tests to demonstrate this plays an important role in the successful development of a vaccine.

WaferOptics® mass volume production and reliability

NASA Astrophysics Data System (ADS)

Wolterink, E.; Demeyer, K.

2010-05-01

The Anteryon WaferOptics® Technology platform contains imaging optics designs, materials, metrologies and combined with wafer level based Semicon & MEMS production methods. WaferOptics® first required complete new system engineering. This system closes the loop between application requirement specifications, Anteryon product specification, Monte Carlo Analysis, process windows, process controls and supply reject criteria. Regarding the Anteryon product Integrated Lens Stack (ILS), new design rules, test methods and control systems were assessed, implemented, validated and customer released for mass production. This includes novel reflowable materials, mastering process, replication, bonding, dicing, assembly, metrology, reliability programs and quality assurance systems. Many of Design of Experiments were performed to assess correlations between optical performance parameters and machine settings of all process steps. Lens metrologies such as FFL, BFL, and MTF were adapted for wafer level production and wafer mapping was introduced for yield management. Test methods for screening and validating suitable optical materials were designed. Critical failure modes such as delamination and popcorning were assessed and modeled with FEM. Anteryon successfully managed to integrate the different technologies starting from single prototypes to high yield mass volume production These parallel efforts resulted in a steep yield increase from 30% to over 90% in a 8 months period.

Method and system for controlling a gasification or partial oxidation process

DOEpatents

Rozelle, Peter L; Der, Victor K

2015-02-10

A method and system for controlling a fuel gasification system includes optimizing a conversion of solid components in the fuel to gaseous fuel components, controlling the flux of solids entrained in the product gas through equipment downstream of the gasifier, and maximizing the overall efficiencies of processes utilizing gasification. A combination of models, when utilized together, can be integrated with existing plant control systems and operating procedures and employed to develop new control systems and operating procedures. Such an approach is further applicable to gasification systems that utilize both dry feed and slurry feed.

Automation Applications in an Advanced Air Traffic Management System : Volume 5A. DELTA Simulation Model - User's Guide

DOT National Transportation Integrated Search

1974-08-01

Volume 4 describes the automation requirements. A presentation of automation requirements is made for an advanced air traffic management system in terms of controller work for-e, computer resources, controller productivity, system manning, failure ef...

Best Manufacturing Practices Survey Conducted at General Dynamics, Fort Worth Division, Fort Worth, Texas

DTIC Science & Technology

1988-05-01

funded by the U.S. Air Force and GDFW. The system will be capable of unmanned operation and will encompass design, engineering , fabrication, and product...Industrial Engineering Production (309) 782-4619 ActivityRock Island, IL Richard Celin Naval Air Engineering Center Production (201) 323-2173 Lakehurst...CONFIGURATION CONTROL Engineering Change Control Room ............................................ 15 Implementatlon af Retofit Changes

Advanced model-based control strategies for the intensification of upstream and downstream processing in mAb production.

PubMed

Papathanasiou, Maria M; Quiroga-Campano, Ana L; Steinebach, Fabian; Elviro, Montaña; Mantalaris, Athanasios; Pistikopoulos, Efstratios N

2017-07-01

Current industrial trends encourage the development of sustainable, environmentally friendly processes with minimal energy and material consumption. In particular, the increasing market demand in biopharmaceutical industry and the tight regulations in product quality necessitate efficient operating procedures that guarantee products of high purity. In this direction, process intensification via continuous operation paves the way for the development of novel, eco-friendly processes, characterized by higher productivity and lower production costs. This work focuses on the development of advanced control strategies for (i) a cell culture system in a bioreactor and (ii) a semicontinuous purification process. More specifically, we consider a fed-batch culture of GS-NS0 cells and the semicontinuous Multicolumn Countercurrent Solvent Gradient Purification (MCSGP) for the purification process. The controllers are designed following the PAROC framework/software platform and their capabilities are assessed in silico, against the process models. It is demonstrated that the proposed controllers efficiently manage to increase the system productivity, returning strategies that can lead to continuous, stable process operation. © 2017 American Institute of Chemical Engineers Biotechnol. Prog., 33:966-988, 2017. © 2017 American Institute of Chemical Engineers.

9 CFR 381.309 - Finished product inspection.

Code of Federal Regulations, 2010 CFR

2010-01-01

... FSIS-approved total quality control system; or (3) Alternative documented procedures that will ensure... contamination, where there is no approved total quality control system, or where the establishment has no... Office of Management and Budget under control number 0583-0015) [51 FR 45634, Dec. 19, 1986, as amended...

Secure Web-based Ground System User Interfaces over the Open Internet

NASA Technical Reports Server (NTRS)

Langston, James H.; Murray, Henry L.; Hunt, Gary R.

1998-01-01

A prototype has been developed which makes use of commercially available products in conjunction with the Java programming language to provide a secure user interface for command and control over the open Internet. This paper reports successful demonstration of: (1) Security over the Internet, including encryption and certification; (2) Integration of Java applets with a COTS command and control product; (3) Remote spacecraft commanding using the Internet. The Java-based Spacecraft Web Interface to Telemetry and Command Handling (Jswitch) ground system prototype provides these capabilities. This activity demonstrates the use and integration of current technologies to enable a spacecraft engineer or flight operator to monitor and control a spacecraft from a user interface communicating over the open Internet using standard World Wide Web (WWW) protocols and commercial off-the-shelf (COTS) products. The core command and control functions are provided by the COTS Epoch 2000 product. The standard WWW tools and browsers are used in conjunction with the Java programming technology. Security is provided with the current encryption and certification technology. This system prototype is a step in the direction of giving scientist and flight operators Web-based access to instrument, payload, and spacecraft data.

Display formats manual

NASA Technical Reports Server (NTRS)

Runnels, R. L.

1973-01-01

The standards and procedures for the generation of operational display formats to be used in the Mission Control Center (MCC) display control system are presented. The required effort, forms, and fundamentals for the design, specifications, and production of display formats are identified. The principles of display design and system constraints controlling the creation of optimum operational displays for mission control are explained. The basic two types of MCC display systems for presenting information are described.

Automated Water-Purification System

NASA Technical Reports Server (NTRS)

Ahlstrom, Harlow G.; Hames, Peter S.; Menninger, Fredrick J.

1988-01-01

Reverse-osmosis system operates and maintains itself with minimal human attention, using programmable controller. In purifier, membranes surround hollow cores through which clean product water flows out of reverse-osmosis unit. No chemical reactions or phase changes involved. Reject water, in which dissolved solids concentrated, emerges from outer membrane material on same side water entered. Flow controls maintain ratio of 50 percent product water and 50 percent reject water. Membranes expected to last from 3 to 15 years.

[Establishment of industry promotion technology system in Chinese medicine secondary exploitation based on "component structure theory"].

PubMed

Cheng, Xu-Dong; Feng, Liang; Zhang, Ming-Hua; Gu, Jun-Fei; Jia, Xiao-Bin

2014-10-01

The purpose of the secondary exploitation of Chinese medicine is to improve the quality of Chinese medicine products, enhance core competitiveness, for better use in clinical practice, and more effectively solve the patient suffering. Herbs, extraction, separation, refreshing, preparation and quality control are all involved in the industry promotion of Chinese medicine secondary exploitation of industrial production. The Chinese medicine quality improvement and industry promotion could be realized with the whole process of process optimization, quality control, overall processes improvement. Based on the "component structure theory", "multi-dimensional structure & process dynamic quality control system" and systematic and holistic character of Chinese medicine, impacts of whole process were discussed. Technology systems of Chinese medicine industry promotion was built to provide theoretical basis for improving the quality and efficacy of the secondary development of traditional Chinese medicine products.

Organic weed control in certified organic watermelon production

USDA-ARS?s Scientific Manuscript database

The increasing perception by consumers that organic food tastes better and is healthier continues to expand the demand for organically produced crops. Field research was conducted in southeast Oklahoma to determine the impact of organic production systems on weed control and watermelon (Citrullus l...

Efforts to reduce exposure at Japanese PWRs: CVCS improvement

DOE Office of Scientific and Technical Information (OSTI.GOV)

Terada, Ryosuke

1995-03-01

Many reports have been focused on the reduction of radiation sources and related occupational exposures. The radiation sources mainly consist of corrosion products. Radiation dose rate is determined by the amount of the activated corrosion products on the surface of the primary loop components of Pressurized Water Reactor (PWR) plants. Therefore, reducing the amount of the corrosion product will contribute to the reduction of occupational exposures. In order to reduce the corrosion products, Chemical and Volume Control System (CVCS) has been improved in Japanese PWRs as follows: (a) Cation Bed Demineralizer Flowrate Control; (b) Hydrogen Peroxide Injection System; (c) Purificationmore » Flowrate During Plant Shutdown; (d) Fine Mesh Filters Upstream of Mixed Bed Demineralizers.« less

A WebGIS system on the base of satellite data processing system for marine application

NASA Astrophysics Data System (ADS)

Gong, Fang; Wang, Difeng; Huang, Haiqing; Chen, Jianyu

2007-10-01

From 2002 to 2004, a satellite data processing system for marine application had been built up in State Key Laboratory of Satellite Ocean Environment Dynamics (Second Institute of Oceanography, State Oceanic Administration). The system received satellite data from TERRA, AQUA, NOAA-12/15/16/17/18, FY-1D and automatically generated Level3 products and Level4 products(products of single orbit and merged multi-orbits products) deriving from Level0 data, which is controlled by an operational control sub-system. Currently, the products created by this system play an important role in the marine environment monitoring, disaster monitoring and researches. Now a distribution platform has been developed on this foundation, namely WebGIS system for querying and browsing of oceanic remote sensing data. This system is based upon large database system-Oracle. We made use of the space database engine of ArcSDE and other middleware to perform database operation in addition. J2EE frame was adopted as development model, and Oracle 9.2 DBMS as database background and server. Simply using standard browsers(such as IE6.0), users can visit and browse the public service information that provided by system, including browsing for oceanic remote sensing data, and enlarge, contract, move, renew, traveling, further data inquiry, attribution search and data download etc. The system is still under test now. Founding of such a system will become an important distribution platform of Chinese satellite oceanic environment products of special topic and category (including Sea surface temperature, Concentration of chlorophyll, and so on), for the exaltation of satellite products' utilization and promoting the data share and the research of the oceanic remote sensing platform.

[Construction of NIRS-based total quality control system for compound Ejiao oral liquid and relative thinking].

PubMed

Zhang, Yan; Zhang, Lu; Tian, Shou-Sheng; Zhou, Xiang-Shan; Li, Wen-Long; Qu, Hai-Bin

2016-10-01

In this paper, near infrared spectroscopy (NIRS)-based total quality control system of compound Ejiao oral liquid is introduced briefly, including the quality control of raw traditional Chinese medicine (TCM) materials, monitoring and control of the extract and the alkaline precipitation technics, and also the inspection of finished products in both open bottle and non-opening modes. By analyzing and summing up the significance and difficulties, several important problems in the practical applications of NIRS technology are proposed, which will provide references for the similar studies of other TCM products. Copyright© by the Chinese Pharmaceutical Association.

Strategies of Production Control as Tools of Efficient Management of Production Enterprises

NASA Astrophysics Data System (ADS)

Budynek, Mateusz; Celińska, Elżbieta; Dybikowska, Adrianna; Kozak, Monika; Ratajczak, Joanna; Urban, Jagoda; Materne, Karolina

2016-03-01

The paper discusses the problem of principle methods of production control as a strategy supporting the production system and stimulating efficient solutions in respect management in production enterprises. The article describes MRP, ERP, JIT, KANBAN and TOC methods and focuses on their main goals, principles of functioning as well as benefits resulting from their application. The methods represent two diverse strategies of production control, i.e. pull and push strategies. Push strategies are used when the plans apply to the first and principle part of production and are based on the demand forecasts. Pull strategies are used when all planning decisions apply to the final stage and depend on the actual demand or orders from customers.

ISO 9000 and/or Systems Engineering Capability Maturity Model?

NASA Technical Reports Server (NTRS)

Gholston, Sampson E.

2002-01-01

For businesses and organizations to remain competitive today they must have processes and systems in place that will allow them to first identify customer needs and then develop products/processes that will meet or exceed the customers needs and expectations. Customer needs, once identified, are normally stated as requirements. Designers can then develop products/processes that will meet these requirements. Several functions, such as quality management and systems engineering management are used to assist product development teams in the development process. Both functions exist in all organizations and both have a similar objective, which is to ensure that developed processes will meet customer requirements. Are efforts in these organizations being duplicated? Are both functions needed by organizations? What are the similarities and differences between the functions listed above? ISO 9000 is an international standard of goods and services. It sets broad requirements for the assurance of quality and for management's involvement. It requires organizations to document the processes and to follow these documented processes. ISO 9000 gives customers assurance that the suppliers have control of the process for product development. Systems engineering can broadly be defined as a discipline that seeks to ensure that all requirements for a system are satisfied throughout the life of the system by preserving their interrelationship. The key activities of systems engineering include requirements analysis, functional analysis/allocation, design synthesis and verification, and system analysis and control. The systems engineering process, when followed properly, will lead to higher quality products, lower cost products, and shorter development cycles. The System Engineering Capability Maturity Model (SE-CMM) will allow companies to measure their system engineering capability and continuously improve those capabilities. ISO 9000 and SE-CMM seem to have a similar objective, which is to document the organization's processes and certify to potential customers the capability of a supplier to control the processes that determine the quality of the product or services being produced. The remaining sections of this report examine the differences and similarities between ISO 9000 and SE-CMM and make recommendations for implementation.

Performance of particulate containment at nanotechnology workplaces

NASA Astrophysics Data System (ADS)

Lo, Li-Ming; Tsai, Candace S.-J.; Dunn, Kevin H.; Hammond, Duane; Marlow, David; Topmiller, Jennifer; Ellenbecker, Michael

2015-11-01

The evaluation of engineering controls for the production or use of carbon nanotubes (CNTs) was investigated at two facilities. These control assessments are necessary to evaluate the current status of control performance and to develop proper control strategies for these workplaces. The control systems evaluated in these studies included ventilated enclosures, exterior hoods, and exhaust filtration systems. Activity-based monitoring with direct-reading instruments and filter sampling for microscopy analysis were used to evaluate the effectiveness of control measures at study sites. Our study results showed that weighing CNTs inside the biological safety cabinet can have a 37 % reduction on the particle concentration in the worker's breathing zone, and produce a 42 % lower area concentration outside the enclosure. The ventilated enclosures used to reduce fugitive emissions from the production furnaces exhibited good containment characteristics when closed, but they failed to contain emissions effectively when opened during product removal/harvesting. The exhaust filtration systems employed for exhausting these ventilated enclosures did not provide promised collection efficiencies for removing engineered nanomaterials from furnace exhaust. The exterior hoods were found to be a challenge for controlling emissions from machining nanocomposites: the downdraft hood effectively contained and removed particles released from the manual cutting process, but using the canopy hood for powered cutting of nanocomposites created 15-20 % higher ultrafine (<500 nm) particle concentrations at the source and at the worker's breathing zone. The microscopy analysis showed that CNTs can only be found at production sources but not at the worker breathing zones during the tasks monitored.

Neural-fuzzy control system application for monitoring process response and control of anaerobic hybrid reactor in wastewater treatment and biogas production.

PubMed

Waewsak, Chaiwat; Nopharatana, Annop; Chaiprasert, Pawinee

2010-01-01

Based on the developed neural-fuzzy control system for anaerobic hybrid reactor (AHR) in wastewater treatment and biogas production, the neural network with backpropagation algorithm for prediction of the variables pH, alkalinity (Alk) and total volatile acids (TVA) at present day time t was used as input data for the fuzzy logic to calculate the influent feed flow rate that was applied to control and monitor the process response at different operations in the initial, overload influent feeding and the recovery phases. In all three phases, this neural-fuzzy control system showed great potential to control AHR in high stability and performance and quick response. Although in the overloading operation phase II with two fold calculating influent flow rate together with a two fold organic loading rate (OLR), this control system had rapid response and was sensitive to the intended overload. When the influent feeding rate was followed by the calculation of control system in the initial operation phase I and the recovery operation phase III, it was found that the neural-fuzzy control system application was capable of controlling the AHR in a good manner with the pH close to 7, TVA/Alk < 0.4 and COD removal > 80% with biogas and methane yields at 0.45 and 0.30 m3/kg COD removed.

Dynamic optimization approach for integrated supplier selection and tracking control of single product inventory system with product discount

NASA Astrophysics Data System (ADS)

Sutrisno; Widowati; Heru Tjahjana, R.

2017-01-01

In this paper, we propose a mathematical model in the form of dynamic/multi-stage optimization to solve an integrated supplier selection problem and tracking control problem of single product inventory system with product discount. The product discount will be stated as a piece-wise linear function. We use dynamic programming to solve this proposed optimization to determine the optimal supplier and the optimal product volume that will be purchased from the optimal supplier for each time period so that the inventory level tracks a reference trajectory given by decision maker with minimal total cost. We give a numerical experiment to evaluate the proposed model. From the result, the optimal supplier was determined for each time period and the inventory level follows the given reference well.

The development and testing of a fieldworthy system of improved fluid pumping device and liquid sensor for oil wells. Fourth quarter technical progress report, 1991

DOE Office of Scientific and Technical Information (OSTI.GOV)

Buckman, W.G.

1991-12-31

A major expenditure to maintain oil and gas leases is the support of pumpers, those individuals who maintain the pumping systems on wells to achieve optimum production. Many leases are marginal and are in remote areas and this requires considerable driving time for the pumper. The Air Pulse Oil Pump System is designed to be an economical system for the shallow stripper wells. To improve on the economics of this system, we have designed a Remote Oil Field Monitor and Controller to enable us to acquire data from the lease to our central office at anytime and to control themore » pumping activities from the central office by using a personal computer. The advent and economics of low-power microcontrollers have made it feasible to use this type of system for numerous remote control systems. We can also adapt this economical system to monitor and control the production of gas wells and/or pump jacks.« less

Control of Bethlehem's coke-oven battery A at Sparrow Point

DOE Office of Scientific and Technical Information (OSTI.GOV)

Michel, A.

1984-02-01

A new 6 m 80-oven compound-fired coke battery capable of producing in excess of 850,000 ton/year began production at Sparrow Point, Maryland, in 1982. The electrical, fuel distribution and control systems are described, together with the computer process control and monitoring systems.

Fuzzy logic controller versus classical logic controller for residential hybrid solar-wind-storage energy system

DOE Office of Scientific and Technical Information (OSTI.GOV)

Derrouazin, A., E-mail: derrsid@gmail.com; Université de Lorraine, LMOPS, EA 4423, 57070 Metz; CentraleSupélec, LMOPS, 57070 Metz

Several researches for management of diverse hybrid energy systems and many techniques have been proposed for robustness, savings and environmental purpose. In this work we aim to make a comparative study between two supervision and control techniques: fuzzy and classic logics to manage the hybrid energy system applied for typical housing fed by solar and wind power, with rack of batteries for storage. The system is assisted by the electric grid during energy drop moments. A hydrogen production device is integrated into the system to retrieve surplus energy production from renewable sources for the household purposes, intending the maximum exploitationmore » of these sources over years. The models have been achieved and generated signals for electronic switches command of proposed both techniques are presented and discussed in this paper.« less

Planning and tracking chemotherapy production for cancer treatment: a performing and integrated solution.

PubMed

Kergosien, Y; Tournamille, J-F; Laurence, B; Billaut, J-C

2011-09-01

Chemotherapy drugs are intended for the treatment of cancer. The production of such drugs and their administration to the patient is a delicate and expensive operation. The study deals with the acquisition and processing of data regarding the production of intravenous chemotherapy, from the production request (the medical prescription), the production itself (pharmaceutical process), to the delivery in the health care unit, for the administration of the chemotherapy. The goal of this study is to develop a system that can schedule, control and track the chemotherapy preparations and satisfy a certification process of quality management ("ISO 9001 version 2000" standard). The solution proposed in this paper was developed within the framework of a common certification process at the Biopharmaceutical Unit of the Oncology Clinic (UBCO) of the Bretonneau hospital in Tours (France). The system consists of two software programs: a software to insure traceability and a decision making software to plan the production. To simplify the data entry process, some mobile entry points with bar code reader have been deployed. These tools enable an accurate tracking of the production, a security and control for the schedule production phases, and a full traceability of each operation leading to the administration of the chemotherapy drug. The first result is a software that creates the production schedule, allows a real time control of the production process and a full traceability of each step. Computational experiments are based on real data sets, with a comparison of a time period before and after the implementation of this solution. The results show the positive impacts of this software, like the reduction of delayed deliveries, real time generation of production indicators, optimization of the production and a saving of staff time. This intuitive system guarantees a traceability in connection with a high quality system certified ISO 9001-v2000 (with a rapid data entry), an assistant to schedule the production of preparations in a better way, a permanent follow-up and analysis of operations. This project proves the benefits of implementing computer solutions for the traceability and assistance in decision making in the hospital systems. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

Coordinated joint motion control system with position error correction

DOEpatents

Danko, George [Reno, NV

2011-11-22

Disclosed are an articulated hydraulic machine supporting, control system and control method for same. The articulated hydraulic machine has an end effector for performing useful work. The control system is capable of controlling the end effector for automated movement along a preselected trajectory. The control system has a position error correction system to correct discrepancies between an actual end effector trajectory and a desired end effector trajectory. The correction system can employ one or more absolute position signals provided by one or more acceleration sensors supported by one or more movable machine elements. Good trajectory positioning and repeatability can be obtained. A two-joystick controller system is enabled, which can in some cases facilitate the operator's task and enhance their work quality and productivity.

Coordinated joint motion control system with position error correction

DOEpatents

Danko, George L.

2016-04-05

Disclosed are an articulated hydraulic machine supporting, control system and control method for same. The articulated hydraulic machine has an end effector for performing useful work. The control system is capable of controlling the end effector for automated movement along a preselected trajectory. The control system has a position error correction system to correct discrepancies between an actual end effector trajectory and a desired end effector trajectory. The correction system can employ one or more absolute position signals provided by one or more acceleration sensors supported by one or more movable machine elements. Good trajectory positioning and repeatability can be obtained. A two joystick controller system is enabled, which can in some cases facilitate the operator's task and enhance their work quality and productivity.

Guidance to employers on integrating e-cigarettes/electronic nicotine delivery systems into tobacco worksite policy.

PubMed

Whitsel, Laurie P; Benowitz, Neal; Bhatnagar, Aruni; Bullen, Chris; Goldstein, Fred; Matthias-Gray, Lena; Grossmeier, Jessica; Harris, John; Isaac, Fikry; Loeppke, Ron; Manley, Marc; Moseley, Karen; Niemiec, Ted; OʼBrien, Vince; Palma-Davis, LaVaughn; Pronk, Nico; Pshock, Jim; Stave, Gregg M; Terry, Paul

2015-03-01

In recent years, new products have entered the marketplace that complicate decisions about tobacco control policies and prevention in the workplace. These products, called electronic cigarettes (e-cigarettes) or electronic nicotine delivery systems, most often deliver nicotine as an aerosol for inhalation, without combustion of tobacco. This new mode of nicotine delivery raises several questions about the safety of the product for the user, the effects of secondhand exposure, how the public use of these products should be handled within tobacco-free and smoke-free air policies, and how their use affects tobacco cessation programs, wellness incentives, and other initiatives to prevent and control tobacco use. In this article, we provide a background on e-cigarettes and then outline key policy recommendations for employers on how the use of these new devices should be managed within worksite tobacco prevention programs and control policies.

Microbial production of hydrogen and ethanol from glycerol-containing wastes discharged from a biodiesel fuel production plant in a bioelectrochemical reactor with thionine.

PubMed

Sakai, Shinsuke; Yagishita, Tatsuo

2007-10-01

H(2) and ethanol production from glycerol-containing wastes discharged from a biodiesel fuel production plant by Enterobacter aerogenes NBRC 12010 was demonstrated in bioelectrochemical cells. Thionine as an exogenous electron transfer mediator was reduced by E. aerogenes, and was re-oxidized by a working electrode applied at +0.2 V against a Ag/AgCl reference electrode by a potentiostat (electrode system). At the initial glycerol concentration of 110 mM, 92.9 mM glycerol was consumed in the electrode system with 2 mM thionine after 48 h. On the other hand, the concentration of glycerol consumed was only 50.3 mM under the control conditions without thionine and the electrodes (normal fermentation). There are no differences in the yields of H(2) and ethanol against glycerol consumed between the control conditions and the conditions with the electrode system. A pH of 6.0 was suitable for the H(2) production in the range between pH 6 and pH 7.5 in the electrode system. At pH values of 7.0 and 7.5, H(2) production decreased and formate was remarkably produced in the reaction solution. The rates of both glycerol consumption and the H(2) and ethanol production increased as the thionine concentration and the surface area of the working electrode increased. After 60 h, 154 mM of the initial 161 mM glycerol concentration in the wastes was consumed in the electrode system, which is a 2.6-fold increase compared to the control experiment. Biotechnol. Bioeng. 2007;98: 340-348. (c) 2007 Wiley Periodicals, Inc.

SIMS prototype system 1 test results: Engineering analysis

NASA Technical Reports Server (NTRS)

1978-01-01

The space and domestic water solar heating system designated SIMS Prototype Systems 1 was evaluated. The test system used 720 ft (gross) of Solar Energy Products Air Collectors, a Solar Control Corporation SAM 20 Air Handler with Model 75-175 control unit, a Jackson Solar Storage tank with Rho Sigma Mod 106 controller, and 20 tons of rack storage. The test data analysis performed evaluates the system performance and documents the suitability of SIMS Prototype System 1 hardware for field installation.

An outline of a risk assessment-based system of meat safety assurance and its future prospects.

PubMed

Berends, B R; van Knapen, F

1999-10-01

Discussed are the outlines of a risk assessment-based system of meat safety assurance to replace the current meat inspection. An example of a system that uses the Hazard Analysis of Critical Control Points (HACCP)-principles in the entire production chain from stable to table is also given. Continuous evaluation of risks is the main driving force of the new system. Only then the system has the means to remain flexible and provide for the data necessary to convince trade partners that the products they buy are safe. A monitoring system that keeps track of the important health hazards in the entire chain from stable to table is therefore necessary. This includes monitoring of cases of disease in the human population caused by the hazardous agents of concern. Coordination of the monitoring and control and processing of the information is done by an independent body. Furthermore, the system demands a production from stable to table that is based on the ideas of Integrated Quality Control (IQC), HACCP, and certification of production processes and quality control procedures. Clear legislation provides for criteria about acceptable or unacceptable health risks for the consumer and determines at what moments which risks should be controlled by the producers. Simultaneously, the legislation has to be flexible enough to be able to adapt quickly to any changes in risks, or in the way risks should be controlled. In the new system current meat inspection can easily be carried out by employees of the slaughter houses and is no longer a direct responsibility of the authorities. The authorities only demand certain safety levels and verify whether producers stick to these. Producers remain fully responsible for the safety and quality of their products, and fully liable in case of any damage to the consumers' health. However, it is to be expected that some EU Member-States miss the organizational and agricultural basis for a successful application of the new system. Consequences are that two parallel flows of meat and meat products may come to existence. One flow will exist of meat produced according to the new, and with respect to safety assurance, superior system. The other flow will consist of meat produced and inspected in the traditional way. However, this meat will contain all the flaws that required a revision of the system in the first place. This, and the fact that EU policy ordains that part-taking in an alternative meat inspection system should be voluntary, may very well result in a very slow start-up of the new system. One of the easiest solutions, however, would be to implement a decontamination step in the slaughtering process, provided that this is accompanied by strict codes of hygienic practices and good manufacturing practices. Not only would this lead to safer meat, but also result in the two separate flows of meat becoming one flow again as well as an easier to organize livestock production according to HACCP-principles.

ECLIPS: An extended CLIPS for backward chaining and goal-directed reasoning

NASA Technical Reports Server (NTRS)

Homeier, Peter V.; Le, Thach C.

1991-01-01

Realistic production systems require an integrated combination of forward and backward reasoning to reflect appropriately the processes of natural human expert reasoning. A control mechanism that consists solely of forward reasoning is not an effective way to promptly focus the system's attention as calculation proceeds. Often, expert system programmers will attempt to compensate for this lack by using data to enforce the desired goal directed control structure. This approach is inherently flawed in that it is attempting to use data to fulfill the role of control. This paper will describe our implementation of backward chaining in C Language Integrated Production System (CLIPS), and show how this has shortened and simplified various CLIPS programs. This work was done at the Aerospace Corporation, and has general applicability.

Identification Of Cells With A Compact Microscope Imaging System With Intelligent Controls

NASA Technical Reports Server (NTRS)

McDowell, Mark (Inventor)

2006-01-01

A Microscope Imaging System (CMIS) with intelligent controls is disclosed that provides techniques for scanning, identifying, detecting and tracking mic?oscopic changes in selected characteristics or features of various surfaces including, but not limited to, cells, spheres, and manufactured products subject to difficult-to-see imperfections. The practice of the present invention provides applications that include colloidal hard spheres experiments, biological cell detection for patch clamping, cell movement and tracking, as well as defect identification in products, such as semiconductor devices, where surface damage can be significant, but difficult to detect. The CMIS system is a machine vision system, which combines intelligent image processing with remote control capabilities and provides the ability to autofocus on a microscope sample, automatically scan an image, and perform machine vision analysis on multiple samples simultaneously.

Tracking of Cells with a Compact Microscope Imaging System with Intelligent Controls

NASA Technical Reports Server (NTRS)

McDowell, Mark (Inventor)

2007-01-01

A Microscope Imaging System (CMIS) with intelligent controls is disclosed that provides techniques for scanning, identifying, detecting and tracking microscopic changes in selected characteristics or features of various surfaces including, but not limited to, cells, spheres, and manufactured products subject to difficult-to-see imperfections. The practice of the present invention provides applications that include colloidal hard spheres experiments, biological cell detection for patch clamping, cell movement and tracking, as well as defect identification in products, such as semiconductor devices, where surface damage can be significant, but difficult to detect. The CMIS system is a machine vision system, which combines intelligent image processing with remote control capabilities and provides the ability to autofocus on a microscope sample, automatically scan an image, and perform machine vision analysis on multiple samples simultaneously

Tracking of cells with a compact microscope imaging system with intelligent controls

NASA Technical Reports Server (NTRS)

McDowell, Mark (Inventor)

2007-01-01

A Microscope Imaging System (CMIS) with intelligent controls is disclosed that provides techniques for scanning, identifying, detecting and tracking microscopic changes in selected characteristics or features of various surfaces including, but not limited to, cells, spheres, and manufactured products subject to difficult-to-see imperfections. The practice of the present invention provides applications that include colloidal hard spheres experiments, biological cell detection for patch clamping, cell movement and tracking, as well as defect identification in products, such as semiconductor devices, where surface damage can be significant, but difficult to detect. The CMIS system is a machine vision system, which combines intelligent image processing with remote control capabilities and provides the ability to auto-focus on a microscope sample, automatically scan an image, and perform machine vision analysis on multiple samples simultaneously.

Operation of a Cartesian Robotic System in a Compact Microscope with Intelligent Controls

NASA Technical Reports Server (NTRS)

McDowell, Mark (Inventor)

2006-01-01

A Microscope Imaging System (CMIS) with intelligent controls is disclosed that provides techniques for scanning, identifying, detecting and tracking microscopic changes in selected characteristics or features of various surfaces including, but not limited to, cells, spheres, and manufactured products subject to difficult-to-see imperfections. The practice of the present invention provides applications that include colloidal hard spheres experiments, biological cell detection for patch clamping, cell movement and tracking, as well as defect identification in products, such as semiconductor devices, where surface damage can be significant, but difficult to detect. The CMIS system is a machine vision system, which combines intelligent image processing with remote control capabilities and provides the ability to autofocus on a microscope sample, automatically scan an image, and perform machine vision analysis on multiple samples simultaneously.

Earth benefits of interdisciplinary CELSS-related research by the NSCORT in Bioregenerative Life Support

NASA Technical Reports Server (NTRS)

Mitchell, C.; Sherman, L.; Nielsen, S.; Nelson, P.; Trumbo, P.; Hodges, T.; Hasegawa, P.; Bressan, R.; Ladisch, M.; Auslander, D.

1996-01-01

Earth benefits of research from the NSCORT in Bioregenerative Life Support will include the following: development of active control mechanisms for light, CO2, and temperature to maximize photosynthesis of crop plants during important phases of crop development; automation of crop culture systems; creation of novel culture systems for optimum productivity; creation of value-added crops with superior nutritional, yield, and waste-process characteristics; environmental control of food and toxicant composition of crops; new process technologies and novel food products for safe, nutritious, palatable vegetarian diets; creation of menus for healthful vegetarian diets with psychological acceptability; enzymatic procedures to degrade recalcitrant crop residues occurring in municipal waste; control-system strategies to ensure sustainabilty of a CELSS that will enable management of diverse complex systems on Earth.

Earth benefits of interdisciplinary celss-related research by the NSCORT in Bioregenerative Life Support

NASA Astrophysics Data System (ADS)

Mitchell, C.; Sherman, L.; Nielsen, S.; Nelson, P.; Trumbo, P.; Hodges, T.; Hasegawa, P.; Bressan, R.; Ladisch, M.; Auslander, D.

Earth benefits of research from the NSCORT in Bioregenerative Life Support will include the following: development of active control mechanisms for light, CO_2, and temperature to maximize photosynthesis of crop plants during important phases of crop development; automation of crop culture systems; creation of novel culture systems for optimum productivity; creation of value-added crops with superior nutritional, yield, and waste-process characteristics; environmental control of food and toxicant composition of crops; new process technologies and novel food products for safe, nutritious, palatable vegetarian diets; creation of menus for healthful vegetarian diets with psychological acceptability; enzymatic procedures to degrade recalcitrant crop residues occurring in municipal waste; control-system strategies to ensure sustainability of a CELSS that will enable management of diverse complex systems on Earth.

Earth benefits of interdisciplinary CELSS-related research by the NSCORT in Bioregenerative Life Support.

PubMed

Mitchell, C; Sherman, L; Nielsen, S; Nelson, P; Trumbo, P; Hodges, T; Hasegawa, P; Bressan, R; Ladisch, M; Auslander, D

1996-01-01

Earth benefits of research from the NSCORT in Bioregenerative Life Support will include the following: development of active control mechanisms for light, CO2, and temperature to maximize photosynthesis of crop plants during important phases of crop development; automation of crop culture systems; creation of novel culture systems for optimum productivity; creation of value-added crops with superior nutritional, yield, and waste-process characteristics; environmental control of food and toxicant composition of crops; new process technologies and novel food products for safe, nutritious, palatable vegetarian diets; creation of menus for healthful vegetarian diets with psychological acceptability; enzymatic procedures to degrade recalcitrant crop residues occurring in municipal waste; control-system strategies to ensure sustainabilty of a CELSS that will enable management of diverse complex systems on Earth.

Development of optical-electronic system for the separation of cullet

NASA Astrophysics Data System (ADS)

Solovey, Alexey A.; Alekhin, Artem A.

2017-06-01

Broken glass being the waste in many fields of production is usually used as a raw material in the production of construction materials. The purity level of collected and processed glass cullet, as a rule, is quite low. Direct usage of these materials without preliminary processing leads to the emergence of defects in the end product or sometimes even to technological downtime. That's why purity control of cullet should be strictly verified. The study shows the method of construction and requirements for an optical-electronic system designed for cullet separation. Moreover, the author proposes a registration channel scheme and shows a scheme of control exposure area. Also the issues of image processing for the implementation of a typical system are examined.

The use of a GIS-based malaria information system for malaria research and control in South Africa.

PubMed

Martin, Carrin; Curtis, Bronwyn; Fraser, Colleen; Sharp, Brian

2002-12-01

The paper aims to outline the innovative development and application of a Geographical Information System based Malaria Information System for malaria research and control in South Africa. This system is a product of collaboration between the Malaria Control Programmes and the Malaria Research Programme of the Medical Research Council of South Africa. The ability of such a system to process data timeously into a usable format is discussed, as well as its relevance to malaria research, appropriate malaria control measures, tourism, and social and economic development.

Co-regulation of polysaccharide production, motility, and expression of type III secretion genes by EnvZ/OmpR and GrrS/GrrA systems in Erwinia amylovora.

PubMed

Li, Wenting; Ancona, Veronica; Zhao, Youfu

2014-02-01

The EnvZ/OmpR and GrrS/GrrA systems, two widely distributed two-component systems in gamma-Proteobacteria, negatively control amylovoran biosynthesis in Erwinia amylovora, and the two systems regulate motility in an opposing manner. In this study, we examined the interplay of EnvZ/OmpR and GrrS/GrrA systems in controlling various virulence traits in E. amylovora. Results showed that amylovoran production was significantly higher when both systems were inactivated, indicating that the two systems act as negative regulators and their combined effect on amylovoran production appears to be enhanced. In contrast, reduced motility was observed when both systems were deleted as compared to that of grrA/grrS mutants and WT strain, indicating that the two systems antagonistically regulate motility in E. amylovora. In addition, glycogen accumulation was much higher in envZ/ompR and two triple mutants than that of grrS/grrA mutants and WT strain, suggesting that EnvZ/OmpR plays a dominant role in regulating glycogen accumulation, whereas levan production was significantly lower in the grrS/grrA and two triple mutants as compared with that of WT and envZ/ompR mutants, indicating that GrrS/GrrA system dominantly controls levan production. Furthermore, both systems negatively regulated expression of three type III secretion (T3SS) genes and their combined negative effect on hrp-T3SS gene expression increased when both systems were deleted. These results demonstrated that EnvZ/OmpR and GrrS/GrrA systems co-regulate various virulence factors in E. amylovora by still unknown mechanisms or through different target genes, sRNAs, or proteins, indicating that a complex regulatory network may be involved, which needs to be further explored.

Quality Control System using Simple Implementation of Seven Tools for Batik Textile Manufacturing

NASA Astrophysics Data System (ADS)

Ragil Suryoputro, Muhammad; Sugarindra, Muchamad; Erfaisalsyah, Hendy

2017-06-01

In order to produce better products and mitigate defect in products, every company must implement a quality control system. Company will find means to implement a quality control system that is capable and reliable. One of the methods is using the simple implementation of the seven tools in quality control defects. The case studied in this research was the level of disability xyz grey fabric on a shuttle loom 2 on the Batik manufacturing company. The seven tools that include: flowchart, check sheet, histogram, scatter diagram combined with control charts, Pareto diagrams and fishbone diagrams (causal diagram). Check sheet results obtained types of defects in the grey fabric was woven xyz is warp, double warp, the warp break, double warp, empty warp, warp tenuous, ugly edges, thick warp, and rust. Based on the analysis of control chart indicates that the process is out of control. This can be seen in the graph control where there is still a lot of outlier data. Based on a scatter diagram shows a positive correlation between the percentage of disability and the number of production. Based on Pareto diagram, repair needs priority is for the dominant type of defect is warp (44%) and based on double warp value histogram is also the highest with a value of 23635.11 m. In addition, based on the analysis of the factors causing defect by fishbone diagram double warp or other types of defects originating from the materials, methods, machines, measurements, man and environment. Thus the company can take to minimize the prevention and repair of defects and improve product quality.

Simulating advanced life support systems to test integrated control approaches

NASA Astrophysics Data System (ADS)

Kortenkamp, D.; Bell, S.

Simulations allow for testing of life support control approaches before hardware is designed and built. Simulations also allow for the safe exploration of alternative control strategies during life support operation. As such, they are an important component of any life support research program and testbed. This paper describes a specific advanced life support simulation being created at NASA Johnson Space Center. It is a discrete-event simulation that is dynamic and stochastic. It simulates all major components of an advanced life support system, including crew (with variable ages, weights and genders), biomass production (with scalable plantings of ten different crops), water recovery, air revitalization, food processing, solid waste recycling and energy production. Each component is modeled as a producer of certain resources and a consumer of certain resources. The control system must monitor (via sensors) and control (via actuators) the flow of resources throughout the system to provide life support functionality. The simulation is written in an object-oriented paradigm that makes it portable, extensible and reconfigurable.

Method, system and computer program product for monitoring and optimizing fluid extraction from geologic strata

DOEpatents

Medizade, Masoud [San Luis Obispo, CA; Ridgely, John Robert [Los Osos, CA

2009-12-15

An arrangement which utilizes an inexpensive flap valve/flow transducer combination and a simple local supervisory control system to monitor and/or control the operation of a positive displacement pump used to extract petroleum from geologic strata. The local supervisory control system controls the operation of an electric motor which drives a reciprocating positive displacement pump so as to maximize the volume of petroleum extracted from the well per pump stroke while minimizing electricity usage and pump-off situations. By reducing the electrical demand and pump-off (i.e., "pounding" or "fluid pound") occurrences, operating and maintenance costs should be reduced sufficiently to allow petroleum recovery from marginally productive petroleum fields. The local supervisory control system includes one or more applications to at least collect flow signal data generated during operation of the positive displacement pump. No flow, low flow and flow duration are easily evaluated using the flap valve/flow transducer arrangement.

Environmental Systems Test Stand

NASA Astrophysics Data System (ADS)

Barta, D.; Young, J.; Ewert, M.; Lee, S.; Wells, P.; Fortson, R.; Castillo, J.

A test stand has been developed for the evaluation of prototype lighting, environmental control and crop cultivation technologies for plant production within an advanced life support system. Design of the test stand was based on preliminary designs of the center growth bay of the Biomass Production Chamber, one of several modules of the Bioregenerative Planetary Life Support Systems Test Complex (BIO- Plex). It consists of two controlled-environment shelves, each with 4.7 m2 of area for crop growth (150 cm width, 315 cm length). There are two chilled water loops, one for operation at conventional temperatures (5-10C) for air temperature and humidity control and one for operation at higher temperatures (15-50C) for waste heat acquisition and heating. Modular light boxes, utilizing either air-cooled or water- jacketed HPS lamps, have been developed. This modular design will allow for easy replacement of new lighting technologies within the light banks. An advanced data acquisition and control system has been developed utilizing localized, networked- based data acquisition modules and programmed with object-based control software.

Bioburden control for Space Station Freedom's Ultrapure Water System

NASA Technical Reports Server (NTRS)

Snodgrass, Donald W.; Rodgers, Elizabeth B.; Obenhuber, Don; Huff, Tim

1991-01-01

Bioburden control is one of the challenges for the Ultrapure Water System on Space Station Freedom. Bioburden control must enable the system to deliver water with a low bacterial count as well as maintain biological contamination at a manageable level, to permit continued production of quality water. Ozone has been chosen as the primary means of Bioburden control. Planned tests to determine the effectiveness of ozone on free-floating microbes and biofilms are described.

Towards sustainable parasite control practices in livestock production with emphasis in Latin America.

PubMed

Henrioud, A Nari

2011-08-04

Endo and ectoparasites of domestic ruminants directly or indirectly contribute to reduce sustainability affecting food security in subsistence or small scale farming systems, food safety (food borne diseases and pesticide residues), environment (pesticides, pollution and ecotoxicity) and farmer's equity (limited or uneven access to relevant technical information/training). This is especially true for some regions of Latin America where there still are huge areas of natural grazing land for cattle, sheep and goats. Sustainable parasite control is not an absolute concept given the different regions and productive systems of the world and therefore, could have different levels of adoption and impact on farmers. This article develops a conceptual framework to better understand where each region or country is situated in terms of attaining a reasonable increase in animal production while preserving sustainability. Within this context the capacity to prioritize the target parasite species for control according to local epidemiology and production systems, the early diagnosis and monitoring of parasite resistance as well as the availability of well trained field professionals acquire a major role, creating an enabling environment for present and future decision support system approaches. Until new and different means of controlling parasites become available; the challenge is to utilize Good Animal Husbandry Practices and Integrated Parasite Management (IPM) principles in a pragmatic way allowing the rational use of pesticides. Copyright © 2011 Elsevier B.V. All rights reserved.

Induced catabolic bio-electrohydrolysis of complex food waste by regulating external resistance for enhancing acidogenic biohydrogen production.

PubMed

Chandrasekhar, K; Venkata Mohan, S

2014-08-01

A novel bio-electrohydrolysis system (BEH) based on self-inducing electrogenic activity was designed as pretreatment device to enhance biohydrogen (H2) production efficiency from food waste. Two-stage hybrid operation with hydrolysis in the initial stage and acidogenic fermentation of the resulting hydrolysate (after hydrolysis) for H2 production in the second stage was evaluated. Application of variable external resistances viz., 10Ω, 100Ω, 1000Ω and closed circuit (CC) influenced the hydrolysis of substrate in BEH system and hydrogen production in acidogenic reactor compared to control. Pretreated substrate at 100Ω documented higher H2 production (1.05l) than 10Ω (0.93l), CC (0.91l), 1000Ω (0.88l) and control operation (0.68l). Comparatively, 10Ω documented higher substrate degradation (53.4%) followed by CC (52.42%), 100Ω (49.51%), 1000Ω (47.57%) and control (43.68%). Voltammetric profiles were in agreement with the observed bio-electrohydrolysis and H2 production efficiency. Copyright © 2014 Elsevier Ltd. All rights reserved.

Automatic control system generation for robot design validation

NASA Technical Reports Server (NTRS)

Bacon, James A. (Inventor); English, James D. (Inventor)

2012-01-01

The specification and drawings present a new method, system and software product for and apparatus for generating a robotic validation system for a robot design. The robotic validation system for the robot design of a robotic system is automatically generated by converting a robot design into a generic robotic description using a predetermined format, then generating a control system from the generic robotic description and finally updating robot design parameters of the robotic system with an analysis tool using both the generic robot description and the control system.

Complementary ecosystem services provided by pest predators and pollinators increase quantity and quality of coffee yields

PubMed Central

Classen, Alice; Peters, Marcell K.; Ferger, Stefan W.; Helbig-Bonitz, Maria; Schmack, Julia M.; Maassen, Genevieve; Schleuning, Matthias; Kalko, Elisabeth K. V.; Böhning-Gaese, Katrin; Steffan-Dewenter, Ingolf

2014-01-01

Wild animals substantially support crop production by providing ecosystem services, such as pollination and natural pest control. However, the strengths of synergies between ecosystem services and their dependencies on land-use management are largely unknown. Here, we took an experimental approach to test the impact of land-use intensification on both individual and combined pollination and pest control services in coffee production systems at Mount Kilimanjaro. We established a full-factorial pollinator and vertebrate exclosure experiment along a land-use gradient from traditional homegardens (agroforestry systems), shaded coffee plantations to sun coffee plantations (total sample size = 180 coffee bushes). The exclusion of vertebrates led to a reduction in fruit set of ca 9%. Pollinators did not affect fruit set, but significantly increased fruit weight of coffee by an average of 7.4%. We found no significant decline of these ecosystem services along the land-use gradient. Pest control and pollination service were thus complementary, contributing to coffee production by affecting the quantity and quality of a major tropical cash crop across different coffee production systems at Mount Kilimanjaro. PMID:24500173

Complementary ecosystem services provided by pest predators and pollinators increase quantity and quality of coffee yields.

PubMed

Classen, Alice; Peters, Marcell K; Ferger, Stefan W; Helbig-Bonitz, Maria; Schmack, Julia M; Maassen, Genevieve; Schleuning, Matthias; Kalko, Elisabeth K V; Böhning-Gaese, Katrin; Steffan-Dewenter, Ingolf

2014-03-22

Wild animals substantially support crop production by providing ecosystem services, such as pollination and natural pest control. However, the strengths of synergies between ecosystem services and their dependencies on land-use management are largely unknown. Here, we took an experimental approach to test the impact of land-use intensification on both individual and combined pollination and pest control services in coffee production systems at Mount Kilimanjaro. We established a full-factorial pollinator and vertebrate exclosure experiment along a land-use gradient from traditional homegardens (agroforestry systems), shaded coffee plantations to sun coffee plantations (total sample size = 180 coffee bushes). The exclusion of vertebrates led to a reduction in fruit set of ca 9%. Pollinators did not affect fruit set, but significantly increased fruit weight of coffee by an average of 7.4%. We found no significant decline of these ecosystem services along the land-use gradient. Pest control and pollination service were thus complementary, contributing to coffee production by affecting the quantity and quality of a major tropical cash crop across different coffee production systems at Mount Kilimanjaro.

Evaluation of pig production practices, constraints and opportunities for improvement in smallholder production systems in Kenya.

PubMed

Mbuthia, Jackson Mwenda; Rewe, Thomas Odiwuor; Kahi, Alexander Kigunzu

2015-02-01

This study evaluated pig production practices by smallholder farmers in two distinct production systems geared towards addressing their constraints and prospects for improvement. The production systems evaluated were semi-intensive and extensive and differed in remoteness, market access, resource availability and pig production intensity. Data were collected using structured questionnaires where a total of 102 pig farmers were interviewed. Qualitative and quantitative research methods were employed to define the socioeconomic characteristics of the production systems, understanding the different roles that pigs play, marketing systems and constraints to production. In both systems, regular cash income and insurance against emergencies were ranked as the main reasons for rearing pigs. Marketing of pigs was mainly driven by the type of production operation. Finances, feeds and housing were identified as the major constraints to production. The study provides important parameters and identifies constraints important for consideration in design of sustainable production improvement strategies. Feeding challenges can be improved through understanding the composition and proper utilization of local feed resources. Provision of adequate housing would improve the stocking rates and control mating.

Establishing a Product Baseline for Global Positioning System Satellites through Functional and Physical Configuration Audits

DTIC Science & Technology

2011-09-01

PBL may see changes as the design is actually implemented . Such changes are typically for practical reasons of adapting to either specific...shall use a configuration management approach to establish and control product attributes and the product baseline across the total system life cycle... practice that helps prevent government interference in subcontracts, holds the prime contractor accountable for their end product (s), limits the potential

ELITE-3 active vibration isolation workstation

NASA Astrophysics Data System (ADS)

Anderson, Eric H.; Houghton, Bowie

2001-06-01

This paper describes the development and capabilities of ELITE-3, a product that incorporates piezoelectric actuators to provide ultrastable work surfaces for very high resolution wafer production, metrology, microscopy, and other applications. The electromechanical, electronic, and software/firmware parts of the ELITE-3 active workstation are described, with an emphasis on considerations relating to the piezoelectric transducers. Performance of the system and its relation to the smart materials is discussed. As the floor beneath a vibration-sensitive instrument supported by ELITE-3 moves, piezoelectrics are controlled to minimize the motion of the instrument. A digital signal processor (DSP) determines the appropriate signals to apply to the actuators. A PC-based interface allows reprogramming of control algorithms and resetting of other parameters within the firmware. The modular product allows incorporation of vibration isolator, actuator and sensor modules into original equipment manufacturer (OEM) products. Alternatively, a workstation can be integrated as an integrated standalone system. The paper describes the system architecture, overall approach to vibration isolation, and various system components, and summarizes motivations for key design approaches.

A Wireless Sensor Network-Based Ubiquitous Paprika Growth Management System

PubMed Central

Hwang, Jeonghwan; Shin, Changsun; Yoe, Hyun

2010-01-01

Wireless Sensor Network (WSN) technology can facilitate advances in productivity, safety and human quality of life through its applications in various industries. In particular, the application of WSN technology to the agricultural area, which is labor-intensive compared to other industries, and in addition is typically lacking in IT technology applications, adds value and can increase the agricultural productivity. This study attempts to establish a ubiquitous agricultural environment and improve the productivity of farms that grow paprika by suggesting a ‘Ubiquitous Paprika Greenhouse Management System’ using WSN technology. The proposed system can collect and monitor information related to the growth environment of crops outside and inside paprika greenhouses by installing WSN sensors and monitoring images captured by CCTV cameras. In addition, the system provides a paprika greenhouse environment control facility for manual and automatic control from a distance, improves the convenience and productivity of users, and facilitates an optimized environment to grow paprika based on the growth environment data acquired by operating the system. PMID:22163543

Modular Systems Of Fixation And Position Jigs In The Production Process For Products And Systems

NASA Astrophysics Data System (ADS)

Babík, Ondrej; Šajgalík, Michal; Zaušková, Lucia; Czán, Andrej

2015-12-01

The project deals with design and implementation of adjustment onto mounting tables in the automotive industry. Manual control system of the jigs is replaced by a pneumatic system. Advantages of the pneumatic system are eliminating service side-time, improving work flow and increasing safety and ergonomics at work. Thanks to higher effectivity of the work process, manpower can be used in other work positions.

Control of autothermal reforming reactor of diesel fuel

NASA Astrophysics Data System (ADS)

Dolanc, Gregor; Pregelj, Boštjan; Petrovčič, Janko; Pasel, Joachim; Kolb, Gunther

2016-05-01

In this paper a control system for autothermal reforming reactor for diesel fuel is presented. Autothermal reforming reactors and the pertaining purification reactors are used to convert diesel fuel into hydrogen-rich reformate gas, which is then converted into electricity by the fuel cell. The purpose of the presented control system is to control the hydrogen production rate and the temperature of the autothermal reforming reactor. The system is designed in such a way that the two control loops do not interact, which is required for stable operation of the fuel cell. The presented control system is a part of the complete control system of the diesel fuel cell auxiliary power unit (APU).

Enhanced polyhydroxyalkanoate production from organic wastes via process control.

PubMed

Vargas, Alejandro; Montaño, Liliana; Amaya, Rodolfo

2014-03-01

This work explores the use of a model-based control scheme to enhance the productivity of polyhroxyalkanoate (PHA) production in a mixed culture two-stage system fed with synthetic wastewater. The controller supplies pulses of substrate while regulating the dissolved oxygen (DO) concentration and uses the data to fit a dynamic mathematical model, which in turn is used to predict the time until the next pulse addition. Experiments in a bench scale system first determined the optimal DO set-point and initial substrate concentration. Then the proposed feedback control strategy was compared with a simpler empiric algorithm. The results show that a substrate conversion rate of 1.370±0.598mgPHA/mgCOD/d was achieved. The proposed strategy can also indicate when to stop the accumulation of PHA upon saturation, which occurred with a PHA content of 71.0±7.2wt.%. Copyright © 2014 Elsevier Ltd. All rights reserved.

An Update on the Conceptual-Production Systems Model of Apraxia: Evidence from Stroke

ERIC Educational Resources Information Center

Stamenova, Vessela; Black, Sandra E.; Roy, Eric A.

2012-01-01

Limb apraxia is a neurological disorder characterized by an inability to pantomime and/or imitate gestures. It is more commonly observed after left hemisphere damage (LHD), but has also been reported after right hemisphere damage (RHD). The Conceptual-Production Systems model (Roy, 1996) suggests that three systems are involved in the control of…

POPEYE: A production rule-based model of multitask supervisory control (POPCORN)

NASA Technical Reports Server (NTRS)

Townsend, James T.; Kadlec, Helena; Kantowitz, Barry H.

1988-01-01

Recent studies of relationships between subjective ratings of mental workload, performance, and human operator and task characteristics have indicated that these relationships are quite complex. In order to study the various relationships and place subjective mental workload within a theoretical framework, we developed a production system model for the performance component of the complex supervisory task called POPCORN. The production system model is represented by a hierarchial structure of goals and subgoals, and the information flow is controlled by a set of condition-action rules. The implementation of this production system, called POPEYE, generates computer simulated data under different task difficulty conditions which are comparable to those of human operators performing the task. This model is the performance aspect of an overall dynamic psychological model which we are developing to examine and quantify relationships between performance and psychological aspects in a complex environment.

The tobacco excise system in Indonesia: hindering effective tobacco control for health.

PubMed

Barber, Sarah; Ahsan, Abdillah

2009-07-01

Comprehensive tobacco control policies include high taxes. This paper describes the tobacco excise structure in Indonesia from 2007 to 2009. The design of the tobacco excise system contributes to neutralizing the effect of a tax increase on consumption. Wide gaps in tax rates allow for the availability of low-priced products, and consumers can substitute to cheaper products in response to price increases. There has been no systematic increase in the tax rates, which promotes affordable of tobacco products. Firms can reduce their prices at point of sale and absorb the tax increase instead of passing it onto consumers. Tiered tax rates by production scale allow firms to evade paying the highest tax brackets legally, thereby increasing profit margins while reducing prices at point of sale. Increases in tobacco excise rates in Indonesia may not have a large health impact under the current system of tax administration.

System-wide hybrid MPC-PID control of a continuous pharmaceutical tablet manufacturing process via direct compaction.

PubMed

Singh, Ravendra; Ierapetritou, Marianthi; Ramachandran, Rohit

2013-11-01

The next generation of QbD based pharmaceutical products will be manufactured through continuous processing. This will allow the integration of online/inline monitoring tools, coupled with an efficient advanced model-based feedback control systems, to achieve precise control of process variables, so that the predefined product quality can be achieved consistently. The direct compaction process considered in this study is highly interactive and involves time delays for a number of process variables due to sensor placements, process equipment dimensions, and the flow characteristics of the solid material. A simple feedback regulatory control system (e.g., PI(D)) by itself may not be sufficient to achieve the tight process control that is mandated by regulatory authorities. The process presented herein comprises of coupled dynamics involving slow and fast responses, indicating the requirement of a hybrid control scheme such as a combined MPC-PID control scheme. In this manuscript, an efficient system-wide hybrid control strategy for an integrated continuous pharmaceutical tablet manufacturing process via direct compaction has been designed. The designed control system is a hybrid scheme of MPC-PID control. An effective controller parameter tuning strategy involving an ITAE method coupled with an optimization strategy has been used for tuning of both MPC and PID parameters. The designed hybrid control system has been implemented in a first-principles model-based flowsheet that was simulated in gPROMS (Process System Enterprise). Results demonstrate enhanced performance of critical quality attributes (CQAs) under the hybrid control scheme compared to only PID or MPC control schemes, illustrating the potential of a hybrid control scheme in improving pharmaceutical manufacturing operations. Copyright © 2013 Elsevier B.V. All rights reserved.

Propulsion system-flight control integration-flight evaluation and technology transition

NASA Technical Reports Server (NTRS)

Burcham, Frank W., Jr.; Gilyard, Glenn B.; Myers, Lawrence P.

1990-01-01

Integration of propulsion and flight control systems and their optimization offering significant performance improvement are assessed. In particular, research programs conducted by NASA on flight control systems and propulsion system-flight control interactions on the YF-12 and F-15 aircraft are addressed; these programs have demonstrated increased thrust, reduced fuel consumption, increased engine life, and improved aircraft performance. Focus is placed on altitude control, speed-Mach control, integrated controller design, as well as flight control systems and digital electronic engine control. A highly integrated digital electronic control program is analyzed and compared with a performance seeking control program. It is shown that the flight evaluation and demonstration of these technologies have been a key part in the transition of the concepts to production and operational use on a timely basis.

Control Systems Engineering in Continuous Pharmaceutical Manufacturing May 20-21, 2014 Continuous Manufacturing Symposium.

PubMed

Myerson, Allan S; Krumme, Markus; Nasr, Moheb; Thomas, Hayden; Braatz, Richard D

2015-03-01

This white paper provides a perspective of the challenges, research needs, and future directions for control systems engineering in continuous pharmaceutical processing. The main motivation for writing this paper is to facilitate the development and deployment of control systems technologies so as to ensure quality of the drug product. Although the main focus is on small-molecule pharmaceutical products, most of the same statements apply to biological drug products. An introduction to continuous manufacturing and control systems is followed by a discussion of the current status and technical needs in process monitoring and control, systems integration, and risk analysis. Some key points are that: (1) the desired objective in continuous manufacturing should be the satisfaction of all critical quality attributes (CQAs), not for all variables to operate at steady-state values; (2) the design of start-up and shutdown procedures can significantly affect the economic operation of a continuous manufacturing process; (3) the traceability of material as it moves through the manufacturing facility is an important consideration that can at least in part be addressed using residence time distributions; and (4) the control systems technologies must assure quality in the presence of disturbances, dynamics, uncertainties, nonlinearities, and constraints. Direct measurement, first-principles and empirical model-based predictions, and design space approaches are described for ensuring that CQA specifications are met. Ways are discussed for universities, regulatory bodies, and industry to facilitate working around or through barriers to the development of control systems engineering technologies for continuous drug manufacturing. Industry and regulatory bodies should work with federal agencies to create federal funding mechanisms to attract faculty to this area. Universities should hire faculty interested in developing first-principles models and control systems technologies for drug manufacturing that are easily transportable to industry. Industry can facilitate the move to continuous manufacturing by working with universities on the conception of new continuous pharmaceutical manufacturing process unit operations that have the potential to make major improvements in product quality, controllability, or reduced capital and/or operating costs. Regulatory bodies should ensure that: (1) regulations and regulatory practices promote, and do not derail, the development and implementation of continuous manufacturing and control systems engineering approaches; (2) the individuals who approve specific regulatory filings are sufficiently trained to make good decisions regarding control systems approaches; (3) provide regulatory clarity and eliminate/reduce regulatory risks; (4) financially support the development of high-quality training materials for use of undergraduate students, graduate students, industrial employees, and regulatory staff; (5) enhance the training of their own technical staff by financially supporting joint research projects with universities in the development of continuous pharmaceutical manufacturing processes and the associated control systems engineering theory, numerical algorithms, and software; and (6) strongly encourage the federal agencies that support research to fund these research areas. © 2014 Wiley Periodicals, Inc. and the American Pharmacists Association. © 2014 Wiley Periodicals, Inc. and the American Pharmacists Association.

Control systems engineering in continuous pharmaceutical manufacturing. May 20-21, 2014 Continuous Manufacturing Symposium.

PubMed

Myerson, Allan S; Krumme, Markus; Nasr, Moheb; Thomas, Hayden; Braatz, Richard D

2015-03-01

This white paper provides a perspective of the challenges, research needs, and future directions for control systems engineering in continuous pharmaceutical processing. The main motivation for writing this paper is to facilitate the development and deployment of control systems technologies so as to ensure quality of the drug product. Although the main focus is on small-molecule pharmaceutical products, most of the same statements apply to biological drug products. An introduction to continuous manufacturing and control systems is followed by a discussion of the current status and technical needs in process monitoring and control, systems integration, and risk analysis. Some key points are that: (1) the desired objective in continuous manufacturing should be the satisfaction of all critical quality attributes (CQAs), not for all variables to operate at steady-state values; (2) the design of start-up and shutdown procedures can significantly affect the economic operation of a continuous manufacturing process; (3) the traceability of material as it moves through the manufacturing facility is an important consideration that can at least in part be addressed using residence time distributions; and (4) the control systems technologies must assure quality in the presence of disturbances, dynamics, uncertainties, nonlinearities, and constraints. Direct measurement, first-principles and empirical model-based predictions, and design space approaches are described for ensuring that CQA specifications are met. Ways are discussed for universities, regulatory bodies, and industry to facilitate working around or through barriers to the development of control systems engineering technologies for continuous drug manufacturing. Industry and regulatory bodies should work with federal agencies to create federal funding mechanisms to attract faculty to this area. Universities should hire faculty interested in developing first-principles models and control systems technologies for drug manufacturing that are easily transportable to industry. Industry can facilitate the move to continuous manufacturing by working with universities on the conception of new continuous pharmaceutical manufacturing process unit operations that have the potential to make major improvements in product quality, controllability, or reduced capital and/or operating costs. Regulatory bodies should ensure that: (1) regulations and regulatory practices promote, and do not derail, the development and implementation of continuous manufacturing and control systems engineering approaches; (2) the individuals who approve specific regulatory filings are sufficiently trained to make good decisions regarding control systems approaches; (3) provide regulatory clarity and eliminate/reduce regulatory risks; (4) financially support the development of high-quality training materials for use of undergraduate students, graduate students, industrial employees, and regulatory staff; (5) enhance the training of their own technical staff by financially supporting joint research projects with universities in the development of continuous pharmaceutical manufacturing processes and the associated control systems engineering theory, numerical algorithms, and software; and (6) strongly encourage the federal agencies that support research to fund these research areas. © 2014 Wiley Periodicals, Inc. and the American Pharmacists Association.

A general assessment of the physiochemical factors that influence leachables accumulation in pharmaceutical drug products and related solutions.

PubMed

Jenke, Dennis

2011-01-01

The accumulation of organic compounds associated with plastic materials into pharmaceutical products and their associated solutions has important suitability for use consequences for those pharmaceutical solutions, most notably in terms of safety and efficacy. The interaction between the pharmaceutical solution and the plastic material is driven and controlled by the same thermodynamic and kinetic factors that regulate the interaction between the constituents of any comparable two-phased system. These physiochemical factors are delineated in this article, and their application to pharmaceutical products is demonstrated. When drug products are packaged in plastic container systems, substances may leach from the container and accumulate in the product. The magnitude of this leaching, and thus the effect that leachables have on the drug product, is controlled by certain thermodynamic and kinetic processes. These factors are described and detailed in this article.

Pharmacy-based distribution system for enteral nutrition products.

PubMed

Craig, S A; Paulson, M F

1985-12-01

A hospital pharmacy department's implementation of enteral nutrition product distribution and its proposal for an enteral nutrition product admixture service are described. Responsibility for the distribution of enteral nutrition formulations was transferred from the central distribution department to the pharmacy after problems with inventory control, billing procedures, and inappropriate administration of enteral nutrition products were recognized by personnel from the central-distribution area and nutrition services. After additional problems were identified using a multi-disciplinary approach, the pharmacy department implemented an enteral nutrition product distribution system and developed an enteral nutrition product formulary. A proposal was developed for a pharmacy-based enteral nutrition admixture service, but implementation of this service was deferred because data from a cost-effectiveness evaluation and random bacteriologic monitoring did not justify adding the service. Pharmacy-based distribution and formulary control of enteral nutrition products alleviated problems with inaccurate patient charges and accumulation of stock on the nursing units. Pharmacists at this hospital hope to develop an enteral nutrition product admixture program that will result in cost savings for the institution.

Hormonal control of angiotensinogen production.

PubMed

Dzau, V J; Herrmann, H C

The renin-angiotensin-aldosterone system appears to be under neural and hormonal control. Plasma angiotensinogen concentration is elevated in Cushing's disease, during pregnancy and in women taking oral contraceptives. An in vitro liver slice system was used to study the hormonal control of angiotensinogen synthesis and release in the rat. Dexamethasone administration in vivo resulted in increase in the in vitro rate of release of angiotensinogen by liver slices into the incubation media. This increase was inhibited by actinomycin D, an inhibitor of protein synthesis and vincristine which blocks secretion. Similarly, ethinyl estradiol treatment resulted in a 50% increase in angiotensinogen production. Hyperthyroid state was achieved by injecting rats with L-thyroxine daily for seven days. Hepatic production rate of angiotensinogen rose 21/2-fold above control and was accompanied by increases in plasma angiotensinogen concentration and plasma renin activity. In contrast, plasma angiotensinogen concentration and plasma renin activity were reduced in thyroidectomized rats. The rate of angiotensinogen production by liver slices of these rats decreased by five-fold below that of intact animals. These changes were largely corrected when thyroidectomized rats were treated with replacement doses of L-thyroxine. We conclude that hepatic angiotensinogen biosynthesis is under hormonal control. Glucocorticoid, estrogen and thyroid hormones all stimulate angiotensinogen production. These results may in part explain the pathogenesis of hypertension associated with certain disease states.

The Controlled Ecological Life Support System Antarctic Analog Project: Prototype Crop Production and Water Treatment System Performance

NASA Technical Reports Server (NTRS)

Bubenheim, David L.; Flynn, Michael T.; Bates, Maynard; Schlick, Greg; Kliss, Mark (Technical Monitor)

1997-01-01

The Controlled Ecological Life Support System (CELSS) Antarctic Analog Project (CAAP), is a joint endeavor between the National Science Foundation, Office of Polar Programs (NSF-OPP) and the NASA. The fundamental objective is to develop, deploy, and operate a testbed of advanced life support technologies at the Amundsen-Scott South Pole Station that enable the objectives of both the NSF and NASA. The functions of food production, water purification, and waste treatment, recycle and reduction provided by CAAP will improve the quality of life for the South Pole inhabitants, reduce logistics dependence, enhance safety and minimize environmental impacts associated with human presence on the polar plateau. Because of the analogous technical, scientific, and mission features with Planetary missions such as a mission to Mars, CAAP provides NASA with a method for validating technologies and overall approaches to supporting humans. Prototype systems for sewage treatment, water recycle and crop production are being evaluated at Ames Research Center. The product water from sewage treatment using a Wiped-Film Rotating Disk is suitable for input to the crop production system. The crop production system has provided an enhanced level of performance compared with projected performance for plant-based life support: an approximate 50% increase in productivity per unit area, more than a 65% decrease in power for plant lighting, and more than a 75% decrease in the total power requirement to produce an equivalent mass of edible biomass.

Multi-method automated diagnostics of rotating machines

NASA Astrophysics Data System (ADS)

Kostyukov, A. V.; Boychenko, S. N.; Shchelkanov, A. V.; Burda, E. A.

2017-08-01

The automated machinery diagnostics and monitoring systems utilized within the petrochemical plants are an integral part of the measures taken to ensure safety and, as a consequence, the efficiency of these industrial facilities. Such systems are often limited in their functionality due to the specifics of the diagnostic techniques adopted. As the diagnostic techniques applied in each system are limited, and machinery defects can have different physical nature, it becomes necessary to combine several diagnostics and monitoring systems to control various machinery components. Such an approach is inconvenient, since it requires additional measures to bring the diagnostic results in a single view of the technical condition of production assets. In this case, we mean by a production facility a bonded complex of a process unit, a drive, a power source and lines. A failure of any of these components will cause an outage of the production asset, which is unacceptable. The purpose of the study is to test a combined use of vibration diagnostics and partial discharge techniques within the diagnostic systems of enterprises for automated control of the technical condition of rotating machinery during maintenance and at production facilities. The described solutions allow you to control the condition of mechanical and electrical components of rotating machines. It is shown that the functionality of the diagnostics systems can be expanded with minimal changes in technological chains of repair and operation of rotating machinery. Automation of such systems reduces the influence of the human factor on the quality of repair and diagnostics of the machinery.

Development of an intelligent controller for power generators

NASA Astrophysics Data System (ADS)

Maxted, Clive; Waller, Winston

2005-01-01

This paper is a description of the development of an embedded controller for high power industrial diesel generators. The aim of the project was to replace the existing discrete logic design by an intelligent versatile and user configurable control system. A prototype embedded PC controlled system was developed, capable of fully replacing the existing system, with a colour TFT display and keypad. Features include fully automatic generator control as before with status and alarm display and monitoring of engine parameters, along with data logging, remote communications and a means of analysing data. The unit was tested on the bench and on diesel generators for the core controlling functionality to prove compliance with the specifications. The results of the testing proved the unit's suitability as a replacement for the existing system in its intended environment. The significance of this study is that a low cost replacement solution has been found for an industrial application by transferring modern technological knowledge to a small business. The company are now able to build on the design and take it into production, reducing servicing and production costs.

A comprehensive review of the implementation of hazard analysis critical control point (HACCP) to the production of flour and flour-based products.

PubMed

Arvanitoyannis, Ioannis S; Traikou, Athina

2005-01-01

The production of flour and semolina and their ensuing products, such as bread, cake, spaghetti, noodles, and corn flakes, is of major importance, because these products constitute some of the main ingredients of the human diet. The Hazard Analysis Critical Control Point (HACCP) system aims at ensuring the safety of these products. HACCP has been implemented within the frame of this study on various products of both Asian and European origin; the hazards, critical control limits (CCLs), observation practices, and corrective actions have been summarized in comprehensive tables. Furthermore, the various production steps, packaging included, were thoroughly analyzed, and reference was made to both the traditional and new methodologies in an attempt to pinpoint the occurring differences (advantages and disadvantages) per process.

Intelligent system of coordination and control for manufacturing

NASA Astrophysics Data System (ADS)

Ciortea, E. M.

2016-08-01

This paper wants shaping an intelligent system monitoring and control, which leads to optimizing material and information flows of the company. The paper presents a model for tracking and control system using intelligent real. Production system proposed for simulation analysis provides the ability to track and control the process in real time. Using simulation models be understood: the influence of changes in system structure, commands influence on the general condition of the manufacturing process conditions influence the behavior of some system parameters. Practical character consists of tracking and real-time control of the technological process. It is based on modular systems analyzed using mathematical models, graphic-analytical sizing, configuration, optimization and simulation.

Certified organic herb mulching demonstration

USDA-ARS?s Scientific Manuscript database

The objective of organo-pestiphytology (the study of organic weed control) is to investigate and develop weed control strategies that are fundamental to the cropping system rather than afterthoughts to a production system. The scarcity of approved organic herbicides reinforces the necessity for org...

Virtual Factory Framework for Supporting Production Planning and Control.

PubMed

Kibira, Deogratias; Shao, Guodong

2017-01-01

Developing optimal production plans for smart manufacturing systems is challenging because shop floor events change dynamically. A virtual factory incorporating engineering tools, simulation, and optimization generates and communicates performance data to guide wise decision making for different control levels. This paper describes such a platform specifically for production planning. We also discuss verification and validation of the constituent models. A case study of a machine shop is used to demonstrate data generation for production planning in a virtual factory.

The mechanics of granitoid systems and maximum entropy production rates.

PubMed

Hobbs, Bruce E; Ord, Alison

2010-01-13

A model for the formation of granitoid systems is developed involving melt production spatially below a rising isotherm that defines melt initiation. Production of the melt volumes necessary to form granitoid complexes within 10(4)-10(7) years demands control of the isotherm velocity by melt advection. This velocity is one control on the melt flux generated spatially just above the melt isotherm, which is the control valve for the behaviour of the complete granitoid system. Melt transport occurs in conduits initiated as sheets or tubes comprising melt inclusions arising from Gurson-Tvergaard constitutive behaviour. Such conduits appear as leucosomes parallel to lineations and foliations, and ductile and brittle dykes. The melt flux generated at the melt isotherm controls the position of the melt solidus isotherm and hence the physical height of the Transport/Emplacement Zone. A conduit width-selection process, driven by changes in melt viscosity and constitutive behaviour, operates within the Transport Zone to progressively increase the width of apertures upwards. Melt can also be driven horizontally by gradients in topography; these horizontal fluxes can be similar in magnitude to vertical fluxes. Fluxes induced by deformation can compete with both buoyancy and topographic-driven flow over all length scales and results locally in transient 'ponds' of melt. Pluton emplacement is controlled by the transition in constitutive behaviour of the melt/magma from elastic-viscous at high temperatures to elastic-plastic-viscous approaching the melt solidus enabling finite thickness plutons to develop. The system involves coupled feedback processes that grow at the expense of heat supplied to the system and compete with melt advection. The result is that limits are placed on the size and time scale of the system. Optimal characteristics of the system coincide with a state of maximum entropy production rate. This journal is © 2010 The Royal Society

Adaptive neural network/expert system that learns fault diagnosis for different structures

NASA Astrophysics Data System (ADS)

Simon, Solomon H.

1992-08-01

Corporations need better real-time monitoring and control systems to improve productivity by watching quality and increasing production flexibility. The innovative technology to achieve this goal is evolving in the form artificial intelligence and neural networks applied to sensor processing, fusion, and interpretation. By using these advanced Al techniques, we can leverage existing systems and add value to conventional techniques. Neural networks and knowledge-based expert systems can be combined into intelligent sensor systems which provide real-time monitoring, control, evaluation, and fault diagnosis for production systems. Neural network-based intelligent sensor systems are more reliable because they can provide continuous, non-destructive monitoring and inspection. Use of neural networks can result in sensor fusion and the ability to model highly, non-linear systems. Improved models can provide a foundation for more accurate performance parameters and predictions. We discuss a research software/hardware prototype which integrates neural networks, expert systems, and sensor technologies and which can adapt across a variety of structures to perform fault diagnosis. The flexibility and adaptability of the prototype in learning two structures is presented. Potential applications are discussed.

PEF and UV combined system for pathogen microorganisms inactivation in liquid food products

NASA Astrophysics Data System (ADS)

Cramariuc, R.; Popa, M.; Tudorache, A.; Brînduşe, E.; Kontek, A.; Mitelut, A.; Fotescu, L.; Cramariuc, B.; Geicu, M.; Nisiparu, L.

2011-06-01

Pulsed electrical field (PEF) treatment is a non-thermal food preservation technology based on the use of the electrical field in impulses applied in order to inactivate and control pathogen microorganisms in foods. This technology is highly appreciated for its ability to prolong the shelf life of the treated product without the use of heat and also for its ability to preserve the product's sensory qualities and nutritional value as well as for the microbiological control of the treated products. This paper presents the PEF and UV treatment methods, or a combination between the two, for microbe inactivation in liquid products. The experiments were carried out using yeasts, lactic bacteria and acetic bacteria in the following systems: stand-alone treatments (PEF or UV) or in combination (UV+PEF or PEF+UV). The results of these experiments showed that one can obtain total inactivation of microorganisms using the combined UV+PEF system, thus leading to the possibility of increasing liquid food products quality as compared to the quality obtained using thermal pasteurization.

Productive Nanosystems: The Physics of Molecular Fabrication

ERIC Educational Resources Information Center

Drexler, K. Eric

2005-01-01

Fabrication techniques are the foundation of physical technology, and are thus of fundamental interest. Physical principles indicate that nanoscale systems will be able to fabricate a wide range of structures, operating with high productivity and precise molecular control. Advanced systems of this kind will require intermediate generations of…

The implementation of a Hazard Analysis and Critical Control Point management system in a peanut butter ice cream plant.

PubMed

Hung, Yu-Ting; Liu, Chi-Te; Peng, I-Chen; Hsu, Chin; Yu, Roch-Chui; Cheng, Kuan-Chen

2015-09-01

To ensure the safety of the peanut butter ice cream manufacture, a Hazard Analysis and Critical Control Point (HACCP) plan has been designed and applied to the production process. Potential biological, chemical, and physical hazards in each manufacturing procedure were identified. Critical control points for the peanut butter ice cream were then determined as the pasteurization and freezing process. The establishment of a monitoring system, corrective actions, verification procedures, and documentation and record keeping were followed to complete the HACCP program. The results of this study indicate that implementing the HACCP system in food industries can effectively enhance food safety and quality while improving the production management. Copyright © 2015. Published by Elsevier B.V.

Electricity production and sludge reduction by integrating microbial fuel cells in anoxic-oxic process.

PubMed

Xiao, Benyi; Luo, Meng; Wang, Xiao; Li, Zuoxing; Chen, Hong; Liu, Junxin; Guo, Xuesong

2017-11-01

To produce energy and reduce sludge production from the treatment of municipal wastewater, four identical microbial fuel cells (MFCs) were constructed in an anoxic-oxic (A/O) process (MFCs-A/O system). Experimental results indicated that this system enhance the removals of chemical oxygen demand (COD) and total nitrogen (TN). The electricity produced by each MFC were ranged from 0.371 to 0.477V (voltage) and from 138 to 227mW/m 3 (power density) at the stable stage, when the external resistance was fixed at 1000Ω. The coulombic efficiency of the MFCs-A/O system ranged from 0.31% to 1.68% (mean=0.72%) at the stable stage, respectively. The removals of COD and TN in the MFCs-A/O system were slightly higher than those in the control system. Compared with the control system, the MFCs-A/O system can reduce waste activated sludge production and sludge yield by 24.0% and 24.2%, respectively. The experimental results indicated that the MFC constructed in A/O system improves wastewater treatment and the MFCs-A/O system can produce electricity while reducing sludge production and increasing wastewater treatment efficiency. Copyright © 2017 Elsevier Ltd. All rights reserved.

A study of interactive control scheduling and economic assessment for robotic systems

NASA Technical Reports Server (NTRS)

1982-01-01

A class of interactive control systems is derived by generalizing interactive manipulator control systems. Tasks of interactive control systems can be represented as a network of a finite set of actions which have specific operational characteristics and specific resource requirements, and which are of limited duration. This has enabled the decomposition of the overall control algorithm simultaneously and asynchronously. The performance benefits of sensor referenced and computer-aided control of manipulators in a complex environment is evaluated. The first phase of the CURV arm control system software development and the basic features of the control algorithms and their software implementation are presented. An optimal solution for a production scheduling problem that will be easy to implement in practical situations is investigated.

Noise Protection

NASA Technical Reports Server (NTRS)

1980-01-01

Environmental Health Systems puts forth an increasing effort in the U.S. to develop ways of controlling noise, particularly in industrial environments due to Federal and State laws, labor union insistence and new findings relative to noise pollution impact on human health. NASA's Apollo guidance control system aided in the development of a noise protection product, SMART. The basis of all SMART products is SMART compound a liquid plastic mixture with exceptional energy/sound absorbing qualities. The basic compound was later refined for noise protection use.

Performance of Particulate Containment at Nanotechnology Workplaces

PubMed Central

Lo, Li-Ming; Tsai, Candace S.-J.; Dunn, Kevin H.; Hammond, Duane; Marlow, David; Topmiller, Jennifer; Ellenbecker, Michael

2015-01-01

The evaluation of engineering controls for the production or use of carbon nanotubes (CNTs) was investigated at two facilities. These controls assessments are necessary to evaluate the current status of control performance and to develop proper control strategies for these workplaces. The control systems evaluated in these studies included ventilated enclosures, exterior hoods, and exhaust filtration systems. Activity-based monitoring with direct-reading instruments and filter sampling for microscopy analysis were used to evaluate the effectiveness of control measures at study sites. Our study results showed that weighing CNTs inside the biological safety cabinet can have a 37% reduction on the particle concentration in the worker’s breathing zone, and produce a 42% lower area concentration outside the enclosure. The ventilated enclosures used to reduce fugitive emissions from the production furnaces exhibited good containment characteristics when closed, but they failed to contain emissions effectively when opened during product removal/harvesting. The exhaust filtration systems employed for exhausting these ventilated enclosures did not provide promised collection efficiencies for removing engineered nanomaterials from furnace exhaust. The exterior hoods were found to be a challenge for controlling emissions from machining nanocomposites: the downdraft hood effectively contained and removed particles released from the manual cutting process, but using the canopy hood for powered cutting of nanocomposites created 15%–20% higher ultrafine (<500 nm) particle concentrations at the source and at the worker’s breathing zone. The microscopy analysis showed that CNTs can only be found at production sources but not at the worker breathing zones during the tasks monitored. PMID:26705393

Development of monitoring and control system for a mine main fan based on frequency converter

NASA Astrophysics Data System (ADS)

Zhang, Y. C.; Zhang, R. W.; Kong, X. Z.; Y Gong, J.; Chen, Q. G.

2013-12-01

In the process of mine exploitation, the requirement of air flow rate often changes. The procedure of traditional control mode of the fan is complex and it is hard to meet the worksite requirement for air. This system is based on Principal Computer (PC) monitoring system and high performance PLC control system. In this system, the frequency converter is adapted to adjust the fan speed and the air of worksite can be regulated steplessly. The function of the monitoring and control system contains on-line monitoring and centralized control. The system can monitor the parameters of fan in real-time, control the operation of frequency converter, as well as, control the fan and its accessory equipments. At the same time, the automation level of the system is highly, the field equipments can be monitored and controlled automatically. So, the system is an important safeguard for mine production.

The Integration of COTS/GOTS within NASA's HST Command and Control System

NASA Technical Reports Server (NTRS)

Pfarr, Thomas; Reis, James E.; Obenschain, Arthur F. (Technical Monitor)

2001-01-01

NASA's mission critical Hubble Space Telescope (HST) command and control system has been re-engineered with COTS/GOTS and minimal custom code. This paper focuses on the design of this new HST Control Center System (CCS) and the lessons learned throughout its development. CCS currently utilizes 31 COTS/GOTS products with an additional 12 million lines of custom glueware code; the new CCS exceeds the capabilities of the original system while significantly reducing the lines of custom code by more than 50%. The lifecycle of COTS/GOTS products will be examined including the pack-age selection process, evaluation process, and integration process. The advantages, disadvantages, issues, concerns, and lessons teamed for integrating COTS/GOTS into the NASA's mission critical HST CCS will be examined in detail. Command and control systems designed with traditional custom code development efforts will be compared with command and control systems designed with new development techniques relying heavily on COTS/COTS integration. This paper will reveal the many hidden costs of COTS/GOTS solutions when compared to traditional custom code development efforts; this paper will show the high cost of COTS/GOTS solutions including training expenses, consulting fees, and long-term maintenance expenses.

Developing Automatic Water Table Control System for Reducing Greenhouse Gas Emissions from Paddy Fields

NASA Astrophysics Data System (ADS)

Arif, C.; Fauzan, M. I.; Satyanto, K. S.; Budi, I. S.; Masaru, M.

2018-05-01

Water table in rice fields play important role to mitigate greenhouse gas (GHG) emissions from paddy fields. Continuous flooding by maintenance water table 2-5 cm above soil surface is not effective and release more GHG emissions. System of Rice Intensification (SRI) as alternative rice farming apply intermittent irrigation by maintaining lower water table is proven can reduce GHG emissions reducing productivity significantly. The objectives of this study were to develop automatic water table control system for SRI application and then evaluate the performances. The control system was developed based on fuzzy logic algorithms using the mini PC of Raspberry Pi. Based on laboratory and field tests, the developed system was working well as indicated by lower MAPE (mean absolute percentage error) values. MAPE values for simulation and field tests were 16.88% and 15.80%, respectively. This system can save irrigation water up to 42.54% without reducing productivity significantly when compared to manual irrigation systems.

A knowledge base browser using hypermedia

NASA Technical Reports Server (NTRS)

Pocklington, Tony; Wang, Lui

1990-01-01

A hypermedia system is being developed to browse CLIPS (C Language Integrated Production System) knowledge bases. This system will be used to help train flight controllers for the Mission Control Center. Browsing this knowledge base will be accomplished either by having navigating through the various collection nodes that have already been defined, or through the query languages.

Intelligent Case Based Decision Support System for Online Diagnosis of Automated Production System

NASA Astrophysics Data System (ADS)

Ben Rabah, N.; Saddem, R.; Ben Hmida, F.; Carre-Menetrier, V.; Tagina, M.

2017-01-01

Diagnosis of Automated Production System (APS) is a decision-making process designed to detect, locate and identify a particular failure caused by the control law. In the literature, there are three major types of reasoning for industrial diagnosis: the first is model-based, the second is rule-based and the third is case-based. The common and major limitation of the first and the second reasonings is that they do not have automated learning ability. This paper presents an interactive and effective Case Based Decision Support System for online Diagnosis (CB-DSSD) of an APS. It offers a synergy between the Case Based Reasoning (CBR) and the Decision Support System (DSS) in order to support and assist Human Operator of Supervision (HOS) in his/her decision process. Indeed, the experimental evaluation performed on an Interactive Training System for PLC (ITS PLC) that allows the control of a Programmable Logic Controller (PLC), simulating sensors or/and actuators failures and validating the control algorithm through a real time interactive experience, showed the efficiency of our approach.

Development and Application of the Key Technologies for the Quality Control and Inspection of National Geographical Conditions Survey Products

NASA Astrophysics Data System (ADS)

Zhao, Y.; Zhang, L.; Ma, W.; Zhang, P.; Zhao, T.

2018-04-01

The First National Geographical Condition Survey is a predecessor task to dynamically master basic situations of the nature, ecology and human activities on the earth's surface and it is the brand-new mapping geographic information engineering. In order to ensure comprehensive, real and accurate survey results and achieve the quality management target which the qualified rate is 100 % and the yield is more than 80 %, it is necessary to carry out the quality control and result inspection for national geographical conditions survey on a national scale. To ensure that achievement quality meets quality target requirements, this paper develops the key technology method of "five-in-one" quality control that is constituted by "quality control system of national geographical condition survey, quality inspection technology system, quality evaluation system, quality inspection information management system and national linked quality control institutions" by aiming at large scale, wide coverage range, more undertaking units, more management levels, technical updating, more production process and obvious regional differences in the national geographical condition survey and combining with novel achievement manifestation, complicated dependency, more special reference data, and large data size. This project fully considering the domestic and foreign related research results and production practice experience, combined with the technology development and the needs of the production, it stipulates the inspection methods and technical requirements of each stage in the quality inspection of the geographical condition survey results, and extends the traditional inspection and acceptance technology, and solves the key technologies that are badly needed in the first national geographic survey.

Publications of the NASA Controlled Ecological Life Support System (CELSS) Program, 1979-1989

NASA Technical Reports Server (NTRS)

Wallace, Janice S.; Powers, Janet V.

1990-01-01

Publications of research sponsored by the NASA Controlled Ecological Life Support System (CELSS) Program from 1979 to 1989 are listed. The CELSS Program encompasses research and technology with the goal of developing an autonomous bioregenerative life support system that continually recycles the solid, liquid, and gaseous materials essential for human life. The bibliography is divided into four major subject areas: food production, nutritional requirements, waste management, and systems management and control.

Computer Programs For Automated Welding System

NASA Technical Reports Server (NTRS)

Agapakis, John E.

1993-01-01

Computer programs developed for use in controlling automated welding system described in MFS-28578. Together with control computer, computer input and output devices and control sensors and actuators, provide flexible capability for planning and implementation of schemes for automated welding of specific workpieces. Developed according to macro- and task-level programming schemes, which increases productivity and consistency by reducing amount of "teaching" of system by technician. System provides for three-dimensional mathematical modeling of workpieces, work cells, robots, and positioners.

Modelling aspects regarding the control in 13C isotope separation column

NASA Astrophysics Data System (ADS)

Boca, M. L.

2016-08-01

Carbon represents the fourth most abundant chemical element in the world, having two stable and one radioactive isotope. The 13Carbon isotopes, with a natural abundance of 1.1%, plays an important role in numerous applications, such as the study of human metabolism changes, molecular structure studies, non-invasive respiratory tests, Alzheimer tests, air pollution and global warming effects on plants [9] A manufacturing control system manages the internal logistics in a production system and determines the routings of product instances, the assignment of workers and components, the starting of the processes on not-yet-finished product instances. Manufacturing control does not control the manufacturing processes themselves, but has to cope with the consequences of the processing results (e.g. the routing of products to a repair station). In this research it was fulfilled some UML (Unified Modelling Language) diagrams for modelling the C13 Isotope Separation column, implement in STARUML program. Being a critical process and needing a good control and supervising, the critical parameters in the column, temperature and pressure was control using some PLC (Programmable logic controller) and it was made some graphic analyze for this to observe some critical situation than can affect the separation process. The main parameters that need to be control are: -The liquid nitrogen (N2) level in the condenser. -The electrical power supplied to the boiler. -The vacuum pressure.

Publications of the NASA Controlled Ecological Life Support Systems (CELSS) Program 1984-86

NASA Technical Reports Server (NTRS)

1987-01-01

Publications of research sponsored by the NASA CELSS (Controlled Ecological Life Support Systems) Program are listed, along with publications of interest to the Program. The bibliography is divided into the three major divisions of CELSS research: (1) Food Production; (2) Waste Management; and (3) Systems Management and Control. This bibliography is an update of NASA CR-3911 and includes references from 1984 through 1986.

Publications of the NASA CELSS (Controlled Ecological Life Support Systems) program

NASA Technical Reports Server (NTRS)

Dufour, P. A.; Solberg, J. L.; Wallace, J. S.

1985-01-01

Publications on research sponsored by the NASA CELSS (controlled ecological life support systems) Program are listed. The bibliography is divided into four areas: (1) human requirements; (2) food production; (3) waste management; and (4) system management and control. The 210 references cover the period from the inception of the CELSS Program (1979) to the present, as well as some earlier publications during the development of the CELSS Program.

MEMS deformable mirror embedded wavefront sensing and control system

NASA Astrophysics Data System (ADS)

Owens, Donald; Schoen, Michael; Bush, Keith

2006-01-01

Electrostatic Membrane Deformable Mirror (MDM) technology developed using silicon bulk micro-machining techniques offers the potential of providing low-cost, compact wavefront control systems for diverse optical system applications. Electrostatic mirror construction using bulk micro-machining allows for custom designs to satisfy wavefront control requirements for most optical systems. An electrostatic MDM consists of a thin membrane, generally with a thin metal or multi-layer high-reflectivity coating, suspended over an actuator pad array that is connected to a high-voltage driver. Voltages applied to the array elements deflect the membrane to provide an optical surface capable of correcting for measured optical aberrations in a given system. Electrostatic membrane DM designs are derived from well-known principles of membrane mechanics and electrostatics, the desired optical wavefront control requirements, and the current limitations of mirror fabrication and actuator drive electronics. MDM performance is strongly dependent on mirror diameter and air damping in meeting desired spatial and temporal frequency requirements. In this paper, we present wavefront control results from an embedded wavefront control system developed around a commercially available high-speed camera and an AgilOptics Unifi MDM driver using USB 2.0 communications and the Linux development environment. This new product, ClariFast TM, combines our previous Clarifi TM product offering into a faster more streamlined version dedicated strictly to Hartmann Wavefront sensing.

To What Degree Does the Promotion System Reward Faculty Research Productivity?

ERIC Educational Resources Information Center

Tien, Flora F.

2007-01-01

This study explores the research question: Does the promotion system in Taiwan reward faculty research productivity? By conducting event history analyses, I have demonstrated that the simple answer to the question is "yes." After controlling for the effects of demography, education, institutions and seniority, the discrete-time logit…

Impacts of anaerobic soil disinfestation and chemical fumigation on soil microbial communities in field tomato production system

USDA-ARS?s Scientific Manuscript database

Anaerobic soil disinfestation (ASD), a potential alternative to chemical fumigation for controlling soilborne pathogens, has been demonstrated in several agricultural production systems. Soil microbial community as affected by ASD is considered one of the major factors responsible for pathogen suppr...

Design of distributed PID-type dynamic matrix controller for fractional-order systems

NASA Astrophysics Data System (ADS)

Wang, Dawei; Zhang, Ridong

2018-01-01

With the continuous requirements for product quality and safety operation in industrial production, it is difficult to describe the complex large-scale processes with integer-order differential equations. However, the fractional differential equations may precisely represent the intrinsic characteristics of such systems. In this paper, a distributed PID-type dynamic matrix control method based on fractional-order systems is proposed. First, the high-order approximate model of integer order is obtained by utilising the Oustaloup method. Then, the step response model vectors of the plant is obtained on the basis of the high-order model, and the online optimisation for multivariable processes is transformed into the optimisation of each small-scale subsystem that is regarded as a sub-plant controlled in the distributed framework. Furthermore, the PID operator is introduced into the performance index of each subsystem and the fractional-order PID-type dynamic matrix controller is designed based on Nash optimisation strategy. The information exchange among the subsystems is realised through the distributed control structure so as to complete the optimisation task of the whole large-scale system. Finally, the control performance of the designed controller in this paper is verified by an example.

The numerical modelling and process simulation for the fault diagnosis of rotary kiln incinerator.

PubMed

Roh, S D; Kim, S W; Cho, W S

2001-10-01

The numerical modelling and process simulation for the fault diagnosis of rotary kiln incinerator were accomplished. In the numerical modelling, two models applied to the modelling within the kiln are the combustion chamber model including the mass and energy balance equations for two combustion chambers and 3D thermal model. The combustion chamber model predicts temperature within the kiln, flue gas composition, flux and heat of combustion. Using the combustion chamber model and 3D thermal model, the production-rules for the process simulation can be obtained through interrelation analysis between control and operation variables. The process simulation of the kiln is operated with the production-rules for automatic operation. The process simulation aims to provide fundamental solutions to the problems in incineration process by introducing an online expert control system to provide an integrity in process control and management. Knowledge-based expert control systems use symbolic logic and heuristic rules to find solutions for various types of problems. It was implemented to be a hybrid intelligent expert control system by mutually connecting with the process control systems which has the capability of process diagnosis, analysis and control.

A randomized controlled trial of skin care protocols for facial resurfacing: lessons learned from the Plastic Surgery Educational Foundation's Skin Products Assessment Research study.

PubMed

Pannucci, Christopher J; Reavey, Patrick L; Kaweski, Susan; Hamill, Jennifer B; Hume, Keith M; Wilkins, Edwin G; Pusic, Andrea L

2011-03-01

The Skin Products Assessment Research Committee was created by the Plastic Surgery Educational Foundation in 2006. The Skin Products Assessment Research study aims were to (1) develop an infrastructure for Plastic Surgery Educational Foundation-conducted, industry-sponsored research in facial aesthetic surgery and (2) test the research process by comparing outcomes of the Obagi Nu-Derm System versus conventional therapy as treatment adjuncts for facial resurfacing procedures. The Skin Products Assessment Research study was designed as a multicenter, double-blind, randomized, controlled trial. The study was conducted in women with Fitzpatrick type I to IV skin, moderate to severe facial photodamage, and periocular and/or perioral fine wrinkles. Patients underwent chemical peel or laser facial resurfacing and were randomized to the Obagi Nu-Derm System or a standard care regimen. The study endpoints were time to reepithelialization, erythema, and pigmentation changes. Fifty-six women were enrolled and 82 percent were followed beyond reepithelialization. There were no significant differences in mean time to reepithelialization between Obagi Nu-Derm System and control groups. The Obagi Nu-Derm System group had a significantly higher median erythema score on the day of surgery (after 4 weeks of product use) that did not persist after surgery. Test-retest photographic evaluations demonstrated that both interrater and intrarater reliability were adequate for primary study outcomes. The authors demonstrated no significant difference in time to reepithelialization between patients who used the Obagi Nu-Derm System or a standard care regimen as an adjunct to facial resurfacing procedures. The Skin Products Assessment Research team has also provided a discussion of future challenges for Plastic Surgery Educational Foundation-sponsored clinical research for readers of this article.

A driven active mass damper by using output of a neural oscillator (effects of position control system changes on vibration mitigation performance)

NASA Astrophysics Data System (ADS)

Hongu, J.; Iba, D.; Sasaki, T.; Nakamura, M.; Moriwaki, I.

2015-03-01

In this paper, a design method for a PD controller, which is a part of a new active mass damper system using a neural oscillator for high-rise buildings, is proposed. The new system mimicking the motion of bipedal mammals is a quite simple system, which has the neural oscillator synchronizing with the acceleration response of the structure. The travel distance and direction of the auxiliary mass of the active mass damper is decided by the output of the neural oscillator, and then, the auxiliary mass is transferred to the decided location by using the PD controller. Therefore, the performance of the PD controller must be evaluated by the vibration energy absorbing efficiency by the system. In order to bring the actual path driven by the PD controller in closer alignment with the ideal path, which is assumed to be a sinusoidal wave under resonance, firstly, the path of the auxiliary mass driven by the PD controller is analytically derived, and the inner product between the vector of ideal and analytical path is evaluated. And then, the PD gain is decided by the maximum value of the inner product. Finally, numerical simulations confirm the validity of the proposed design method of the PD controller.

A system for the management of requests at an image data bank. M.S. Thesis

NASA Technical Reports Server (NTRS)

Debarrosaguirre, J. L. (Principal Investigator)

1984-01-01

An automated system was implemented to supersede existing manual procedures in fulfilling user requests made to a remote sensing data bank, concerning specifically LANDSAT imagery. The system controls the several production steps from request entry to the shipment of each final product. Special solutions and techniques were employed due to the severe limitations, in both hardware and software of the host minicomputer system.

The role of the production scheduling system in rescheduling

NASA Astrophysics Data System (ADS)

Kalinowski, K.; Grabowik, C.; Kempa, W.; Paprocka, I.

2015-11-01

The paper presents the rescheduling problem in the context of cooperation between production scheduling system (PSS) and other units in an integrated manufacturing environment - decision makers and software systems. The main aim is to discuss the PSS functionality for maximizing automation of the rescheduling process, reducing the response time and improving the quality of generated solutions. PSSs operate in the meeting of tactical and operational level of planning and control, and play an important role in the production preparation and control. On the basis of information about orders, technology and production system state (e.g. resources availability) they prepare and/or update a detailed plan of production flow - a schedule. All necessary data for scheduling and rescheduling are usually collected in other systems both from organizational and technical production preparation, e.g. ERP, PLM, MES, CAPP or others, as well as they are entered directly by the decision- makers/operators. Data acquired in this way are often incomplete and inconsistent. Therefore the existing rescheduling software works according to interactive method - rather support but does not replace the human decision maker in tasks planning. When rescheduling, due to the limited amount of time to make a decision this interaction is particularly important. An additional problem arises in data acquisition, in the process of data exchanging between systems or in the identification of new data sources and their processing. Different approaches to rescheduling were characterized, including those solutions, where all these operations are carried out by an autonomous system and those in which scheduling is performed only upon request from the outside, for the newly created scheduling data representing the current state of the production system.

Dynamic optimization of CELSS crop photosynthetic rate by computer-assisted feedback control

NASA Astrophysics Data System (ADS)

Chun, C.; Mitchell, C. A.

1997-01-01

A procedure for dynamic optimization of net photosynthetic rate (Pn) for crop production in Controlled Ecological Life-Support Systems (CELSS) was developed using leaf lettuce as a model crop. Canopy Pn was measured in real time and fed back for environmental control. Setpoints of photosynthetic photon flux (PPF) and CO_2 concentration for each hour of the crop-growth cycle were decided by computer to reach a targeted Pn each day. Decision making was based on empirical mathematical models combined with rule sets developed from recent experimental data. Comparisons showed that dynamic control resulted in better yield per unit energy input to the growth system than did static control. With comparable productivity parameters and potential for significant energy savings, dynamic control strategies will contribute greatly to the sustainability of space-deployed CELSS.

Farmers’ Intentions to Implement Foot and Mouth Disease Control Measures in Ethiopia

PubMed Central

Jemberu, Wudu T.; Mourits, M. C. M.; Hogeveen, H.

2015-01-01

The objectives of this study were to explore farmers’ intentions to implement foot and mouth disease (FMD) control in Ethiopia, and to identify perceptions about the disease and its control measures that influence these intentions using the Health Belief Model (HBM) framework. Data were collected using questionnaires from 293 farmers in three different production systems. The influence of perceptions on the intentions to implement control measures were analyzed using binary logistic regression. The effect of socio-demographic and husbandry variables on perceptions that were found to significantly influence the intentions were analyzed using ordinal logistic regression. Almost all farmers (99%) intended to implement FMD vaccination free of charge. The majority of farmers in the pastoral (94%) and market oriented (92%) systems also had the intention to implement vaccination with charge but only 42% of the crop-livestock mixed farmers had the intention to do so. Only 2% of pastoral and 18% of crop-livestock mixed farmers had the intention to implement herd isolation and animal movement restriction continuously. These proportions increased to 11% for pastoral and 50% for crop-livestock mixed farmers when the measure is applied only during an outbreak. The majority of farmers in the market oriented system (>80%) had the intention to implement herd isolation and animal movement restriction measure, both continuously and during an outbreak. Among the HBM perception constructs, perceived barrier was found to be the only significant predictor of the intention to implement vaccination. Perceived susceptibility, perceived benefit and perceived barrier were the significant predictors of the intention for herd isolation and animal movement restriction measure. In turn, the predicting perceived barrier on vaccination control varied significantly with the production system and the age of farmers. The significant HBM perception predictors on herd isolation and animal movement restriction control were significantly influenced only by the type of production system. The results of this study indicate that farmers’ intentions to apply FMD control measures are variable among production systems, an insight which is relevant in the development of future control programs. Promotion programs aimed at increasing farmers’ motivation to participate in FMD control by charged vaccination or animal movement restriction should give attention to the perceived barriers influencing the intentions to apply these measures. PMID:26375391

Farmers' Intentions to Implement Foot and Mouth Disease Control Measures in Ethiopia.

PubMed

Jemberu, Wudu T; Mourits, M C M; Hogeveen, H

2015-01-01

The objectives of this study were to explore farmers' intentions to implement foot and mouth disease (FMD) control in Ethiopia, and to identify perceptions about the disease and its control measures that influence these intentions using the Health Belief Model (HBM) framework. Data were collected using questionnaires from 293 farmers in three different production systems. The influence of perceptions on the intentions to implement control measures were analyzed using binary logistic regression. The effect of socio-demographic and husbandry variables on perceptions that were found to significantly influence the intentions were analyzed using ordinal logistic regression. Almost all farmers (99%) intended to implement FMD vaccination free of charge. The majority of farmers in the pastoral (94%) and market oriented (92%) systems also had the intention to implement vaccination with charge but only 42% of the crop-livestock mixed farmers had the intention to do so. Only 2% of pastoral and 18% of crop-livestock mixed farmers had the intention to implement herd isolation and animal movement restriction continuously. These proportions increased to 11% for pastoral and 50% for crop-livestock mixed farmers when the measure is applied only during an outbreak. The majority of farmers in the market oriented system (>80%) had the intention to implement herd isolation and animal movement restriction measure, both continuously and during an outbreak. Among the HBM perception constructs, perceived barrier was found to be the only significant predictor of the intention to implement vaccination. Perceived susceptibility, perceived benefit and perceived barrier were the significant predictors of the intention for herd isolation and animal movement restriction measure. In turn, the predicting perceived barrier on vaccination control varied significantly with the production system and the age of farmers. The significant HBM perception predictors on herd isolation and animal movement restriction control were significantly influenced only by the type of production system. The results of this study indicate that farmers' intentions to apply FMD control measures are variable among production systems, an insight which is relevant in the development of future control programs. Promotion programs aimed at increasing farmers' motivation to participate in FMD control by charged vaccination or animal movement restriction should give attention to the perceived barriers influencing the intentions to apply these measures.

Automation of testing modules of controller ELSY-ТМК

NASA Astrophysics Data System (ADS)

Dolotov, A. E.; Dolotova, R. G.; Petuhov, D. V.; Potapova, A. P.

2017-01-01

In modern life, there are means for automation of various processes which allow one to provide high quality standards of released products and to raise labour efficiency. In the given paper, the data on the automation of the test process of the ELSY-TMK controller [1] is presented. The ELSY-TMK programmed logic controller is an effective modular platform for construction of automation systems for small and average branches of industrial production. The modern and functional standard of communication and open environment of the logic controller give a powerful tool of wide spectrum applications for industrial automation. The algorithm allows one to test controller modules by operating the switching system and external devices faster and at a higher level of quality than a human without such means does.

Environmental Assessment for the Space Based Infrared System (SBIRS) Mission Control Station for Defense Support Program Consolidation

DTIC Science & Technology

1996-04-01

use of products containing hazardous materials (e.g., cleaning products , spray and liquid solvents, toner cartridges, etc.). The total quantity of...products containing hazardous materials (e.g., cleaning products , spray and liquid solvents, toner cartridges, etc.). The total quantity of hazardous

Algorithm and data support of traffic congestion forecasting in the controlled transport

NASA Astrophysics Data System (ADS)

Dmitriev, S. V.

2015-06-01

The topicality of problem of the traffic congestion forecasting in the logistic systems of product movement highways is considered. The concepts: the controlled territory, the highway occupancy by vehicles, the parking and the controlled territory are introduced. Technical realizabilityof organizing the necessary flow of information on the state of the transport system for its regulation has been marked. Sequence of practical implementation of the solution is given. An algorithm for predicting traffic congestion in the controlled transport system is suggested.

Advanced thermal control for spacecraft applications

NASA Astrophysics Data System (ADS)

Hardesty, Robert; Parker, Kelsey

2015-09-01

In optical systems just like any other space borne system, thermal control plays an important role. In fact, most advanced designs are plagued with volume constraints that further complicate the thermal control challenges for even the most experienced systems engineers. Peregrine will present advances in satellite thermal control based upon passive heat transfer technologies to dissipate large thermal loads. This will address the use of 700 W/m K and higher conducting products that are five times better than aluminum on a specific basis providing enabling thermal control while maintaining structural support.

Global regulators ExpA (GacA) and KdgR modulate extracellular enzyme gene expression through the RsmA-rsmB system in Erwinia carotovora subsp. carotovora.

PubMed

Hyytiäinen, H; Montesano, M; Palva, E T

2001-08-01

The production of the main virulence determinants, the extracellular plant cell wall-degrading enzymes, and hence virulence of Erwinia carotovora subsp. carotovora is controlled by a complex regulatory network. One of the global regulators, the response regulator ExpA, a GacA homolog, is required for transcriptional activation of the extracellular enzyme genes of this soft-rot pathogen. To elucidate the mechanism of ExpA control as well as interactions with other regulatory systems, we isolated second-site transposon mutants that would suppress the enzyme-negative phenotype of an expA (gacA) mutant. Inactivation of kdgR resulted in partial restoration of extracellular enzyme production and virulence to the expA mutant, suggesting an interaction between the two regulatory pathways. This interaction was mediated by the RsmA-rsmB system. Northern analysis was used to show that the regulatory rsmB RNA was under positive control of ExpA. Conversely, the expression of rsmA encoding a global repressor was under negative control of ExpA and positive control of KdgR. This study indicates a central role for the RsmA-rsmB regulatory system during pathogenesis, integrating signals from the ExpA (GacA) and KdgR global regulators of extracellular enzyme production in E. carotovora subsp. carotovora.

A fuzzy-logic-based controller for methane production in anaerobic fixed-film reactors.

PubMed

Robles, A; Latrille, E; Ruano, M V; Steyer, J P

2017-01-01

The main objective of this work was to develop a controller for biogas production in continuous anaerobic fixed-bed reactors, which used effluent total volatile fatty acids (VFA) concentration as control input in order to prevent process acidification at closed loop. To this aim, a fuzzy-logic-based control system was developed, tuned and validated in an anaerobic fixed-bed reactor at pilot scale that treated industrial winery wastewater. The proposed controller varied the flow rate of wastewater entering the system as a function of the gaseous outflow rate of methane and VFA concentration. Simulation results show that the proposed controller is capable to achieve great process stability even when operating at high VFA concentrations. Pilot results showed the potential of this control approach to maintain the process working properly under similar conditions to the ones expected at full-scale plants.

First report of Dolichozele koebelei Viereck, 1911 (Hymenoptera: Braconidae) on larvae of Spodoptera frugiperda (J. E. Smith, 1797) (Lepidoptera: Noctuidae) in maize (Zea mays L.) under different cropping systems.

PubMed

Silva, R B; Cruz, I; Penteado-Dias, A M

2014-08-01

In the context of the modern agriculture, pest control is important in order to increase productivity in maize (Zea mays L.). However, this control should be done rationally, prioritising environmentally safer methods such as biological control. This paper aims to report the occurrence of Dolichozele koebelei Viereck, 1911 (Hymenoptera: Braconidae) in Spodoptera frugiperda (J. E. Smith, 1797) (Lepidoptera: Noctuidae) larvae collected in maize subjected to different cropping systems. The experiment was conducted at the Centro Nacional de Pesquisa de Milho e Sorgo (CNPMS) in Sete Lagoas, Minas Gerais State, Brazil, using organic and conventional production. Ten plants were sampled from each of the 24 plots and for each production system, three times a week during the entire cycle of maize (variety BR 106). In the laboratory, larvae were distributed in individual rearing containers with artificial diet until the end of the biological cycle. An increased number of S. frugiperda larvae was observed in organic single crop maize; hence a higher percentage of S. frugiperda larvae parasitised by Hymenoptera and Diptera also occurred in the maize under this production system. Dolichozele koebelei had not yet been described in association with larvae of S. frugiperda. The percentage of parasitism of S. frugiperda larvae was high in both experiments, indicating the importance of natural control agents in reducing the population density of S. frugiperda, and especially the importance of an appropriate crop management.

Optimal Control Inventory Stochastic With Production Deteriorating

NASA Astrophysics Data System (ADS)

Affandi, Pardi

2018-01-01

In this paper, we are using optimal control approach to determine the optimal rate in production. Most of the inventory production models deal with a single item. First build the mathematical models inventory stochastic, in this model we also assume that the items are in the same store. The mathematical model of the problem inventory can be deterministic and stochastic models. In this research will be discussed how to model the stochastic as well as how to solve the inventory model using optimal control techniques. The main tool in the study problems for the necessary optimality conditions in the form of the Pontryagin maximum principle involves the Hamilton function. So we can have the optimal production rate in a production inventory system where items are subject deterioration.

Performance evaluation of the croissant production line with reparable machines

NASA Astrophysics Data System (ADS)

Tsarouhas, Panagiotis H.

2015-03-01

In this study, the analytical probability models for an automated serial production system, bufferless that consists of n-machines in series with common transfer mechanism and control system was developed. Both time to failure and time to repair a failure are assumed to follow exponential distribution. Applying those models, the effect of system parameters on system performance in actual croissant production line was studied. The production line consists of six workstations with different numbers of reparable machines in series. Mathematical models of the croissant production line have been developed using Markov process. The strength of this study is in the classification of the whole system in states, representing failures of different machines. Failure and repair data from the actual production environment have been used to estimate reliability and maintainability for each machine, workstation, and the entire line is based on analytical models. The analysis provides a useful insight into the system's behaviour, helps to find design inherent faults and suggests optimal modifications to upgrade the system and improve its performance.

40 CFR 141.90 - Reporting requirements.

Code of Federal Regulations, 2012 CFR

2012-07-01

... water system deemed to have optimized corrosion control under § 141.81(b)(3), a water system subject to...), and switching corrosion inhibitor products (e.g., orthophosphate to blended phosphate). Long-term... changed. (c) Corrosion control treatment reporting requirements. By the applicable dates under § 141.81...

40 CFR 141.90 - Reporting requirements.

Code of Federal Regulations, 2010 CFR

2010-07-01

... water system deemed to have optimized corrosion control under § 141.81(b)(3), a water system subject to...), and switching corrosion inhibitor products (e.g., orthophosphate to blended phosphate). Long-term... changed. (c) Corrosion control treatment reporting requirements. By the applicable dates under § 141.81...

40 CFR 141.90 - Reporting requirements.

Code of Federal Regulations, 2014 CFR

2014-07-01

... water system deemed to have optimized corrosion control under § 141.81(b)(3), a water system subject to...), and switching corrosion inhibitor products (e.g., orthophosphate to blended phosphate). Long-term... changed. (c) Corrosion control treatment reporting requirements. By the applicable dates under § 141.81...

40 CFR 141.90 - Reporting requirements.

Code of Federal Regulations, 2011 CFR

2011-07-01

... water system deemed to have optimized corrosion control under § 141.81(b)(3), a water system subject to...), and switching corrosion inhibitor products (e.g., orthophosphate to blended phosphate). Long-term... changed. (c) Corrosion control treatment reporting requirements. By the applicable dates under § 141.81...

40 CFR 141.90 - Reporting requirements.

Code of Federal Regulations, 2013 CFR

2013-07-01

... water system deemed to have optimized corrosion control under § 141.81(b)(3), a water system subject to...), and switching corrosion inhibitor products (e.g., orthophosphate to blended phosphate). Long-term... changed. (c) Corrosion control treatment reporting requirements. By the applicable dates under § 141.81...

The crop growth research chamber

NASA Technical Reports Server (NTRS)

Wagenbach, Kimberly

1993-01-01

The Crop Growth Research Chamber (CGRC) has been defined by CELSS principle investigators and science advisory panels as a necessary ground-based tool in the development of a regenerative life support system. The focus of CGRC research will be on the biomass production component of the CELSS system. The ground-based Crop Growth Research Chamber is for the study of plant growth and development under stringently controlled environments isolated from the external environment. The chamber has importance in three areas of CELSS activities: (1) crop research; (2) system control and integration, and (3) flight hardware design and experimentation. The laboratory size of the CGRC will be small enough to allow duplication of the unit, the conducting of controlled experiments, and replication of experiments, but large enough to provide information representative of larger plant communities. Experiments will focus on plant growth in a wide variety of environments and the effects of those environments on plant production of food, water, oxygen, toxins, and microbes. To study these effects in a closed system, tight control of the environment is necessary.

Consideration in selecting crops for the human-rated life support system: a Linear Programming model

NASA Technical Reports Server (NTRS)

Wheeler, E. F.; Kossowski, J.; Goto, E.; Langhans, R. W.; White, G.; Albright, L. D.; Wilcox, D.; Henninger, D. L. (Principal Investigator)

1996-01-01

A Linear Programming model has been constructed which aids in selecting appropriate crops for CELSS (Controlled Environment Life Support System) food production. A team of Controlled Environment Agriculture (CEA) faculty, staff, graduate students and invited experts representing more than a dozen disciplines, provided a wide range of expertise in developing the model and the crop production program. The model incorporates nutritional content and controlled-environment based production yields of carefully chosen crops into a framework where a crop mix can be constructed to suit the astronauts' needs. The crew's nutritional requirements can be adequately satisfied with only a few crops (assuming vitamin mineral supplements are provided) but this will not be satisfactory from a culinary standpoint. This model is flexible enough that taste and variety driven food choices can be built into the model.

Consideration in selecting crops for the human-rated life support system: a linear programming model

NASA Astrophysics Data System (ADS)

Wheeler, E. F.; Kossowski, J.; Goto, E.; Langhans, R. W.; White, G.; Albright, L. D.; Wilcox, D.

A Linear Programming model has been constructed which aids in selecting appropriate crops for CELSS (Controlled Environment Life Support System) food production. A team of Controlled Environment Agriculture (CEA) faculty, staff, graduate students and invited experts representing more than a dozen disciplines, provided a wide range of expertise in developing the model and the crop production program. The model incorporates nutritional content and controlled-environment based production yields of carefully chosen crops into a framework where a crop mix can be constructed to suit the astronauts' needs. The crew's nutritional requirements can be adequately satisfied with only a few crops (assuming vitamin mineral supplements are provided) but this will not be satisfactory from a culinary standpoint. This model is flexible enough that taste and variety driven food choices can be built into the model.

A CLIPS expert system for maximizing alfalfa (Medicago Sativa L.) production

NASA Technical Reports Server (NTRS)

Engel, B. A.; Jones, D. D.; Rhykerd, R. L.; Rhykerd, L. M.; Rhykerd, C. L., Jr.; Rhykerd, C. L.

1990-01-01

An alfalfa management expert system originally developed by Purdue University agricultural scientists on the PC Plus expert system shell from Texas Instrument has been updated and successfully converted to CLIPS (C Language Integrated Production System). This reduces the cost and legal restrictions associated with making the expert system available to agribusiness industries, extension personnel and farm managers and operators. The expert system includes recommendations concerning soil drainage, liming, P and K fertilization, weed control, variety selection and seeding rate including pure live seeds.

Control of accidental releases of hydrogen selenide in vented storage cabinets

NASA Astrophysics Data System (ADS)

Fthenakis, V. M.; Moskowitz, P. D.; Sproull, R. D.

1988-07-01

Highly toxic hydrogen selenide and hydrogen sulfide gases are used in the production of copper-indium-diselenide photovoltaic cells by reactive sputtering. In the event of an accident, these gases may be released to the atmosphere and pose hazards to public and occupational safety and health. This paper outlines an approach for designing systems for the control of these releases given the uncertainty in release conditions and lack of data on the chemical systems involved. Accidental releases of these gases in storage cabinets can be controlled by either a venturi and packed-bed scrubber and carbon adsorption bed, or containment scrubbing equipment followed by carbon adsorption. These systems can effectively reduce toxic gas emissions to levels needed to protect public health. The costs of these controls (˜0.012/Wp) are samll in comparison with current (˜6/Wp) and projected (˜I/Wp) production costs.

Controlled environment crop production - Hydroponic vs. lunar regolith

NASA Technical Reports Server (NTRS)

Bugbee, Bruce G.; Salisbury, Frank B.

1989-01-01

The potential of controlled environment crop production in a lunar colony is discussed. Findings on the effects of optimal root-zone and aerial environments derived as part of the NASA CELSS project at Utah State are presented. The concept of growing wheat in optimal environment is discussed. It is suggested that genetic engineering might produce the ideal wheat cultivar for CELSS (about 100 mm in height with fewer leaves). The Utah State University hydroponic system is outlined and diagrams of the system and plant container construction are provided. Ratio of plant mass to solution mass, minimum root-zone volume, maintenance, and pH control are discussed. A comparison of liquid hydrophonic systems and lunar regoliths as substrates for plant growth is provided. The physiological processes that are affected by the root-zone environment are discussed including carbon partitioning, nutrient availability, nutrient absorption zones, root-zone oxygen, plant water potential, root-produced hormones, and rhizosphere pH control.

Control area trends: Principles and responses

DOE Office of Scientific and Technical Information (OSTI.GOV)

Day, L.R.

1995-04-01

Two trends impacting the control of interconnected system operations are on a collision course. Like two strong weather fronts, the combination of these trends can generate tornados or gentle rain. Better system control and improved system security can be the result if there is productive cooperation, commitment, communication, and control. Computers and communication networks are the tools used to turn the momentum of these two trends to the advantage of the industry. But before the first line of software can be written, the cooperation, commitment, and communication of the interested parties must establish the parameters for future system control andmore » operations. This article examines how the control of interconnected system operations is being affected by the consolidation of control areas and the introduction of new control areas.« less

Research and development of intelligent controller for high-grade sanitary ware

NASA Astrophysics Data System (ADS)

Bao, Kongjun; Shen, Qingping

2013-03-01

With the social and economic development and people's living standards improve, more and more emphasis on modern society, people improve the quality of family life, the use of intelligent controller applications in high-grade sanitary ware physiotherapy students. Analysis of high-grade sanitary ware physiotherapy common functions pointed out in the production and use of the possible risks, proposed implementation of the system hardware and matching, given the system software implementation process. High-grade sanitary ware physiotherapy intelligent controller not only to achieve elegant and beautiful, simple, physical therapy, water power, deodorant, multi-function, intelligent control, to meet the consumers, the high-end sanitary ware market, strong demand, Accelerate the enterprise product Upgrade and improve the competitiveness of enterprises.

Action-based language: a theory of language acquisition, comprehension, and production.

PubMed

Glenberg, Arthur M; Gallese, Vittorio

2012-07-01

Evolution and the brain have done a marvelous job solving many tricky problems in action control, including problems of learning, hierarchical control over serial behavior, continuous recalibration, and fluency in the face of slow feedback. Given that evolution tends to be conservative, it should not be surprising that these solutions are exploited to solve other tricky problems, such as the design of a communication system. We propose that a mechanism of motor control, paired controller/predictor models, has been exploited for language learning, comprehension, and production. Our account addresses the development of grammatical regularities and perspective, as well as how linguistic symbols become meaningful through grounding in perception, action, and emotional systems. Copyright © 2011 Elsevier Srl. All rights reserved.

Proactive detection of bones in poultry processing

NASA Astrophysics Data System (ADS)

Daley, W. D. R.; Stewart, John

2009-05-01

Bones continue to be a problem of concern for the poultry industry. Most further processed products begin with the requirement for raw material with minimal bones. The current process for generating deboned product requires systems for monitoring and inspecting the output product. The current detection systems are either people palpitating the product or X-ray systems. The current performance of these inspection techniques are below the desired levels of accuracies and are costly. We propose a technique for monitoring bones that conduct the inspection operation in the deboning the process so as to have enough time to take action to reduce the probability that bones will end up in the final product. This is accomplished by developing active cones with built in illumination to backlight the cage (skeleton) on the deboning line. If the bones of interest are still on the cage then the bones are not in the associated meat. This approach also allows for the ability to practice process control on the deboning operation to keep the process under control as opposed to the current system where the detection is done post production and does not easily present the opportunity to adjust the process. The proposed approach shows overall accuracies of about 94% for the detection of the clavicle bones.

Overlapping Networks Engaged during Spoken Language Production and Its Cognitive Control

PubMed Central

Wise, Richard J.S.; Mehta, Amrish; Leech, Robert

2014-01-01

Spoken language production is a complex brain function that relies on large-scale networks. These include domain-specific networks that mediate language-specific processes, as well as domain-general networks mediating top-down and bottom-up attentional control. Language control is thought to involve a left-lateralized fronto-temporal-parietal (FTP) system. However, these regions do not always activate for language tasks and similar regions have been implicated in nonlinguistic cognitive processes. These inconsistent findings suggest that either the left FTP is involved in multidomain cognitive control or that there are multiple spatially overlapping FTP systems. We present evidence from an fMRI study using multivariate analysis to identify spatiotemporal networks involved in spoken language production in humans. We compared spoken language production (Speech) with multiple baselines, counting (Count), nonverbal decision (Decision), and “rest,” to pull apart the multiple partially overlapping networks that are involved in speech production. A left-lateralized FTP network was activated during Speech and deactivated during Count and nonverbal Decision trials, implicating it in cognitive control specific to sentential spoken language production. A mirror right-lateralized FTP network was activated in the Count and Decision trials, but not Speech. Importantly, a second overlapping left FTP network showed relative deactivation in Speech. These three networks, with distinct time courses, overlapped in the left parietal lobe. Contrary to the standard model of the left FTP as being dominant for speech, we revealed a more complex pattern within the left FTP, including at least two left FTP networks with competing functional roles, only one of which was activated in speech production. PMID:24966373

Overlapping networks engaged during spoken language production and its cognitive control.

PubMed

Geranmayeh, Fatemeh; Wise, Richard J S; Mehta, Amrish; Leech, Robert

2014-06-25

Spoken language production is a complex brain function that relies on large-scale networks. These include domain-specific networks that mediate language-specific processes, as well as domain-general networks mediating top-down and bottom-up attentional control. Language control is thought to involve a left-lateralized fronto-temporal-parietal (FTP) system. However, these regions do not always activate for language tasks and similar regions have been implicated in nonlinguistic cognitive processes. These inconsistent findings suggest that either the left FTP is involved in multidomain cognitive control or that there are multiple spatially overlapping FTP systems. We present evidence from an fMRI study using multivariate analysis to identify spatiotemporal networks involved in spoken language production in humans. We compared spoken language production (Speech) with multiple baselines, counting (Count), nonverbal decision (Decision), and "rest," to pull apart the multiple partially overlapping networks that are involved in speech production. A left-lateralized FTP network was activated during Speech and deactivated during Count and nonverbal Decision trials, implicating it in cognitive control specific to sentential spoken language production. A mirror right-lateralized FTP network was activated in the Count and Decision trials, but not Speech. Importantly, a second overlapping left FTP network showed relative deactivation in Speech. These three networks, with distinct time courses, overlapped in the left parietal lobe. Contrary to the standard model of the left FTP as being dominant for speech, we revealed a more complex pattern within the left FTP, including at least two left FTP networks with competing functional roles, only one of which was activated in speech production. Copyright © 2014 Geranmayeh et al.

Automated Job Controller for Clouds and the Earth's Radiant Energy System (CERES) Production Processing

NASA Astrophysics Data System (ADS)

Gleason, J. L.; Hillyer, T. N.

2011-12-01

Clouds and the Earth's Radiant Energy System (CERES) is one of NASA's highest priority Earth Observing System (EOS) scientific instruments. The CERES science team will integrate data from the CERES Flight Model 5 (FM5) on the NPOESS Preparatory Project (NPP) in addition to the four CERES scanning instrument on Terra and Aqua. The CERES production system consists of over 75 Product Generation Executives (PGEs) maintained by twelve subsystem groups. The processing chain fuses CERES instrument observations with data from 19 other unique sources. The addition of FM5 to over 22 instrument years of data to be reprocessed from flight models 1-4 creates a need for an optimized production processing approach. This poster discusses a new approach, using JBoss and Perl to manage job scheduling and interdependencies between PGEs and external data sources. The new optimized approach uses JBoss to serve handler servlets which regulate PGE-level job interdependencies and job completion notifications. Additional servlets are used to regulate all job submissions from the handlers and to interact with the operator. Perl submission scripts are used to build Process Control Files and to interact directly with the operating system and cluster scheduler. The result is a reduced burden on the operator by algorithmically enforcing a set of rules that determine the optimal time to produce data products with the highest integrity. These rules are designed on a per PGE basis and periodically change. This design provides the means to dynamically update PGE rules at run time and increases the processing throughput by using an event driven controller. The immediate notification of a PGE's completion (an event) allows successor PGEs to launch at the proper time with minimal start up latency, thereby increasing computer system utilization.

[Monitoring strategy for control of tobacco in Mexico: advertising, promotion and sponsorship, packaging and labeling].

PubMed

Rodríguez-Bolaños, Rosibel; Reynales-Shigematsu, Luz Myriam; Ibañez-Hernández, Norma A; Santos-Luna, René; Valdés-Salgado, Raydel; Avila-Tang, Erika; Stillman, Frances

2010-01-01

To describe strategies used in the publicity, marketing, and sale, of tobacco products in 12 cities in Mexico. Tobacco products points of sale (POS) were identified within a 500 m radius of Global Youth Tobacco Survey (2005-2006) schools. We used observational surveys and an online Geographic Information System (GIS). In the 257 schools visited, we found, on average, 8.3 stores and 5 street vendors around each of them. Forty-four percent of the stores had interior tobacco publicity, 8.3% had tobacco products at children's eye level, 6.5% had some promotion, 33.6% had a no selling to minors sign, and 44.4% of stores and 58.8% of street vendors sold single cigarettes. Tobacco products are largely publicized and marketed around schools. There is no compliance of tobacco control legislation in regards to selling to minors and single cigarettes. It is necessary to implement a surveillance system to monitor strategies for tobacco control and the tobacco industry.

Product Structure, the Heart of Product Definition

NASA Technical Reports Server (NTRS)

DeHoog, C., Jr.

1999-01-01

This paper describes the LMMSS Product Definition System (PDS) philosophy and approach were the use of each item parts document or software can be traced to a specific end item (EI) serial/tail number of the product. It explains why a part-oriented approach to data organization and configuration management is required. The definition of part-oriented is that all appropriate product definition data products will be collected. Referenced and managed by their linkage/relationship to parts/items, The paper will touch upon how LMMSS store/controls product definition information under each project's top product designator in a two tiered approach. One tier for each product end item and another tier which contain/controls listings of drawings, documents. Specifications and standards that are required for hardware item definition.

Dopamine Mediates the Vagal Modulation of the Immune System by Electroacupuncture

PubMed Central

Torres-Rosas, Rafael; Yehia, Ghassan; Peña, Geber; Mishra, Priya; del Rocio Thompson-Bonilla, Maria; Moreno-Eutimio, Mario Adán; Arriaga-Pizano, Lourdes Andrea; Isibasi, Armando; Ulloa, Luis

2014-01-01

Previous anti-inflammatory strategies against sepsis, a leading cause of death in hospitals, had limited efficacy in clinical trials, in part because they targeted single cytokines and the experimental models failed to mimic clinical settings1-3. Neuronal networks represent physiological mechanisms selected by evolution to control inflammation that can be exploited for the treatment of inflammatory and infectious disorders3. Here, we report that sciatic nerve activation with electroacupuncture controls systemic inflammation and rescues mice from polymicrobial peritonitis. Electroacupuncture at the sciatic nerve controls systemic inflammation by inducing a vagal activation of DOPA decarboxylase leading to the production of dopamine in the adrenal medulla. Experimental models with adrenolectomized animals mimic clinical adrenal insufficiency4, increase the susceptibility to sepsis, and prevent the anti-inflammatory potential of electroacupuncture. Dopamine inhibits cytokine production via dopaminergic type-1 receptors. Dopaminergic D1-agonists suppress systemic inflammation and rescue mice from polymicrobial peritonitis in animals with adrenal insufficiency. Our results suggest a novel anti-inflammatory mechanism mediated by the sciatic and the vagus nerves modulating the production of catecholamines in the adrenal glands. From a pharmacological perspective, selective dopaminergic agonists mimic the anti-inflammatory potential of electroacupuncture and can provide therapeutic advantages to control inflammation in infectious and inflammatory disorders. PMID:24562381

Zebra finch mates use their forebrain song system in unlearned call communication.

PubMed

Ter Maat, Andries; Trost, Lisa; Sagunsky, Hannes; Seltmann, Susanne; Gahr, Manfred

2014-01-01

Unlearned calls are produced by all birds whereas learned songs are only found in three avian taxa, most notably in songbirds. The neural basis for song learning and production is formed by interconnected song nuclei: the song control system. In addition to song, zebra finches produce large numbers of soft, unlearned calls, among which "stack" calls are uttered frequently. To determine unequivocally the calls produced by each member of a group, we mounted miniature wireless microphones on each zebra finch. We find that group living paired males and females communicate using bilateral stack calling. To investigate the role of the song control system in call-based male female communication, we recorded the electrical activity in a premotor nucleus of the song control system in freely behaving male birds. The unique combination of acoustic monitoring together with wireless brain recording of individual zebra finches in groups shows that the neuronal activity of the song system correlates with the production of unlearned stack calls. The results suggest that the song system evolved from a brain circuit controlling simple unlearned calls to a system capable of producing acoustically rich, learned vocalizations.

Zebra Finch Mates Use Their Forebrain Song System in Unlearned Call Communication

PubMed Central

Ter Maat, Andries; Trost, Lisa; Sagunsky, Hannes; Seltmann, Susanne; Gahr, Manfred

2014-01-01

Unlearned calls are produced by all birds whereas learned songs are only found in three avian taxa, most notably in songbirds. The neural basis for song learning and production is formed by interconnected song nuclei: the song control system. In addition to song, zebra finches produce large numbers of soft, unlearned calls, among which “stack” calls are uttered frequently. To determine unequivocally the calls produced by each member of a group, we mounted miniature wireless microphones on each zebra finch. We find that group living paired males and females communicate using bilateral stack calling. To investigate the role of the song control system in call-based male female communication, we recorded the electrical activity in a premotor nucleus of the song control system in freely behaving male birds. The unique combination of acoustic monitoring together with wireless brain recording of individual zebra finches in groups shows that the neuronal activity of the song system correlates with the production of unlearned stack calls. The results suggest that the song system evolved from a brain circuit controlling simple unlearned calls to a system capable of producing acoustically rich, learned vocalizations. PMID:25313846

Controller's role in monitoring prospective payment system.

PubMed

Margrif, F D

1986-05-01

The challenge for hospital controllers in overseeing the prospective payment system (PPS) lies not in acquiring technical expertise but in working with the chief executive officer to coordinate organizational change. Specifically, the controller should assist in creating a prospective payment committee (PPC)--an interdisciplinary group of executives, middle managers, and medical staff. The PPC's duties, among others, include educating staff about the PPS, development of a productivity reporting system, and review of the responsibility accounting structure.

Controlled ecological life support systems; Proceedings of Workshop II of the 26th COSPAR Plenary Meeting, Toulouse, France, June 30-July 11, 1986

NASA Technical Reports Server (NTRS)

Macelroy, R. D. (Editor); Smernoff, D. T. (Editor)

1987-01-01

The present conference on the development status of Controlled Ecological Life Support Systems (CELSSs) discusses food production and gas exchange with the Spirulina blue-green alga, biomass recycling for greater energy efficiency in algal culture CELSSs, algal proteins for food processing in a CELSS, a CELSS with photosynthetic N2-fixing cyanobacteria, the NASA CELSS program, and vapor compression ditillation and membrane technology for water revitalization. Also discussed are a fundamental study of CELSS gas monitoring, the application of catalytic wet oxidation to CELSS, a large-scale perspective on ecosystems, Japanese CELSS research activities, the use of potatoes in bioregenerative life-support, wheat production in controlled environments, and a trickle water and feeding system in plant culture.

Promising More Information

NASA Technical Reports Server (NTRS)

2003-01-01

When NASA needed a real-time, online database system capable of tracking documentation changes in its propulsion test facilities, engineers at Stennis Space Center joined with ECT International, of Brookfield, Wisconsin, to create a solution. Through NASA's Dual-Use Program, ECT developed Exdata, a software program that works within the company's existing Promise software. Exdata not only satisfied NASA s requirements, but also expanded ECT s commercial product line. Promise, ECT s primary product, is an intelligent software program with specialized functions for designing and documenting electrical control systems. An addon to AutoCAD software, Promis e generates control system schematics, panel layouts, bills of material, wire lists, and terminal plans. The drawing functions include symbol libraries, macros, and automatic line breaking. Primary Promise customers include manufacturing companies, utilities, and other organizations with complex processes to control.

Large deviation analysis of a simple information engine

NASA Astrophysics Data System (ADS)

Maitland, Michael; Grosskinsky, Stefan; Harris, Rosemary J.

2015-11-01

Information thermodynamics provides a framework for studying the effect of feedback loops on entropy production. It has enabled the understanding of novel thermodynamic systems such as the information engine, which can be seen as a modern version of "Maxwell's Dæmon," whereby a feedback controller processes information gained by measurements in order to extract work. Here, we analyze a simple model of such an engine that uses feedback control based on measurements to obtain negative entropy production. We focus on the distribution and fluctuations of the information obtained by the feedback controller. Significantly, our model allows an analytic treatment for a two-state system with exact calculation of the large deviation rate function. These results suggest an approximate technique for larger systems, which is corroborated by simulation data.

Microbial control of hydrogen sulfide production

DOE Office of Scientific and Technical Information (OSTI.GOV)

Montgomery, A.D.; Bhupathiraju, V.K.; Wofford, N.

1995-12-31

A sulfide-resistant strain of Thiobacillus denitrificans, strain F, prevented the accumulation of sulfide by Desulfovibrio desulfuricans when both organisms were grown in liquid medium. The wild-type strain of T. denitrificans did not prevent the accumulation of sulfide produced by D. desulfuricans. Strain F also prevented the accumulation of sulfide by a mixed population of sulfate-reducing bacteria enriched from an oil field brine. Fermentation balances showed that strain F stoichiometrically oxidized the sulfide produced by D. desulfuricans and the oil field brine enrichment to sulfate. The ability of a strain F to control sulfide production in an experimental system of coresmore » and formation water from the Redfield, Iowa, natural gas storage facility was also investigated. A stable, sulfide-producing biofilm was established in two separate core systems, one of which was inoculated with strain F while the other core system (control) was treated in an identical manner, but was not inoculated with strain F. When formation water with 10 mM acetate and 5 mM nitrate was injected into both core systems, the effluent sulfide concentrations in the control core system ranged from 200 to 460 {mu}M. In the test core system inoculated with strain F, the effluent sulfide concentrations were lower, ranging from 70 to 110 {mu}M. In order to determine whether strain F could control sulfide production under optimal conditions for sulfate-reducing bacteria, the electron donor was changed to lactate and inorganic nutrients (nitrogen and phosphate sources) were added to the formation water. When nutrient-supplemented formation water with 3.1 mM lactate and 10 mM nitrate was used, the effluent sulfide concentrations of the control core system initially increased to about 3,800 {mu}M, and then decreased to about 1,100 {mu}M after 5 weeks. However, in the test core system inoculated with strain F, the effluent sulfide concentrations were much lower, 160 to 330 {mu}M.« less

21 CFR 111.105 - What must quality control personnel do?

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 2 2010-04-01 2010-04-01 false What must quality control personnel do? 111.105..., LABELING, OR HOLDING OPERATIONS FOR DIETARY SUPPLEMENTS Production and Process Control System: Requirements for Quality Control § 111.105 What must quality control personnel do? Quality control personnel must...

Trichinae certification in the United States pork industry.

PubMed

Pyburn, David G; Gamble, H Ray; Wagstrom, Elizabeth A; Anderson, Lowell A; Miller, Lawrence E

2005-09-05

Control of Trichinella infection in U.S. pork has traditionally been accomplished by inspection of individual carcasses at slaughter or by post-slaughter processing to inactivate parasites. We propose that an alternative to individual carcass testing or processing can be used when pigs are raised in production systems where risk of exposure to Trichinella spiralis has been mitigated. Declines in prevalence of this parasite in U.S. domestic swine during the last 30 years, coupled with improvements in pork production systems, now allow Trichinella control to be shifted to the farm through implementation of specific pork production practices. Knowledge of risk factors for exposure of swine to T. spiralis was used to develop an objective audit of risk that can be applied to pork production sites. In a pilot study, 461 production site audits were performed by trained veterinary practitioners. The on-farm audit included aspects of farm management, bio-security, feed and feed storage, rodent control programs and general hygiene. Of the 461 production site audits, 450 audits (97.6%) indicated compliance with the required good production practices. These sites are eligible for certification under the U.S. Trichinae Certification Program and will be audited regularly to maintain that status. The described trichinae certification mechanism will establish a process for ensuring the Trichinella safety of swine, and ultimately food products derived from swine, at the production level.

Integration of a mechanical forebody vortex control system into the F-15

NASA Technical Reports Server (NTRS)

Boalbey, Richard E.; Citurs, Kevin D.; Ely, Wayne L.; Harbaugh, Stephen P.; Hollingsworth, William B.; Phillips, Ronald L.

1994-01-01

The goal of the F-15 Forebody Vortex Control (FVC) program is to develop a production FVC system for the F-15. The system may consist of either a mechanically actuated device such as the strakes developed for the HARV program, or a pneumatic device such as the port blowing system being tested on the X-29. Both types of systems are being evaluated under this program. Background information on the F-15 and a description and overview of forebody vortex controls (FVC) will be presented.

Analog design of wireless control for home equipment

NASA Astrophysics Data System (ADS)

Zheng, Shiyong; Li, Zhao; Li, Biqing; Jiang, Suping

2018-04-01

This design consists of a STC89C52 microcontroller, a serial Bluetooth module and the Android system. Production of STC89C52 controlled by single-chip computer telephone systems. The system is composed of mobile phone Android system as a master in the family centre,via serial Bluetooth module pass instructions and information to implement wireless transceiver using STC89C52 MCU wireless Bluetooth transmission to control homedevices. System high reliability, low cost easy to use, stong applicability and other characerristics, can be used in single-user family, has great significance.

Mars inflatable greenhouse analog.

PubMed

Sadler, Philip D; Giacomelli, Gene A

2002-01-01

Light intensities on the Martian surface can possibly support a bioregenerative life support system (BLSS) utilizing natural sunlight for hydroponic crop production, if a suitable controlled environment can be provided. Inflatable clear membrane structures offer low mass, are more easily transported than a rigid structure, and are good candidates for providing a suitable controlled environment for crop production. Cable culture is one hydroponic growing system that can take advantage of the beneficial attributes of the inflatable structure. An analog of a Mars inflatable greenhouse can provide researchers data on issues such as crew time requirements for operation, productivity for BLSS, human factors, and much more at a reasonable cost. This is a description of one such design.

Analysis of modern technologies commonly used in beef cattle production: conventional beef production versus nonconventional production using meta-analysis.

PubMed

Wileman, B W; Thomson, D U; Reinhardt, C D; Renter, D G

2009-10-01

Conventional feeding systems use pharmaceutical products not allowed in natural or organic systems for finishing cattle. This review of data compares the performance effects (ADG, G:F, DMI) of technologies used in conventional feeding programs that are prohibited in organic programs, natural programs, or both. The technologies evaluated were steroid implants, monensin, tylosin, endectocides, and metaphylaxis with any antimicrobial. For inclusion in this analysis, studies were conducted in North America, reported randomization to treatment group, used beef cattle, contained an untreated control group, and were sourced from peer-reviewed journals. Forest plots were used to examine the data visually for trends toward a uniform effect of the technology on the outcomes of interest (ADG, DMI, G:F). Technologies that displayed a uniform response on the forest plot compared with negative controls were then analyzed using mixed models. Examination of forest plots for endectocides, steroid implants, monensin, and metaphylaxis technologies appeared to show performance advantages for treated cattle relative to cattle in negative control groups. An insufficient number of studies met the inclusion criteria to conduct meta-analyses comparing endectocides, monensin, or tylosin with negative controls. Average daily gain in feeder cattle given metaphylaxis on arrival was 0.11 kg/d (P < 0.01) greater relative to cattle that did not receive metaphylaxis on arrival. Implanting heifers increased ADG by 0.08 kg/d compared with nonimplanted controls (P = 0.09). Implants had no effect on G:F (P = 0.14) in heifers or on DMI (P = 0.44) relative to nonimplanted control heifers. Implanting steers was associated with greater ADG, by 0.25 kg/d (P < 0.01), and DMI, by 0.53 kg/d (P < 0.01), relative to nonimplanted control steers. Implants also improved G:F in steers relative to nonimplanted steers, by 0.02 (0.17 vs. 0.15; implanted vs. controls, P < 0.01; n = 21 studies). When average estimated differences in ADG and G:F for implanted and nonimplanted steers were incorporated into a breakeven model, implanted steers had a $77/animal lower cost of production than nonimplanted steers and a $349/animal lower cost of production than organically raised steers. These data illustrate the importance of capturing premiums when operating natural and organic production systems to maintain economic viability.

Determination of production run time and warranty length under system maintenance and trade credits

NASA Astrophysics Data System (ADS)

Tsao, Yu-Chung

2012-12-01

Manufacturers offer a warranty period within which they will fix failed products at no cost to customers. Manufacturers also perform system maintenance when a system is in an out-of-control state. Suppliers provide a credit period to settle the payment to manufacturers. This study considers manufacturer's production and warranty decisions for an imperfect production system under system maintenance and trade credit. Specifically, this study uses the economic production quantity to model the decisions under system maintenance and trade credit. These decisions involve how long the production run time and warranty length should be to maximise total profit. This study provides lemmas for the conditions of optimality and develops a theorem and an algorithm for solving the problems described. Numerical examples illustrate the solution procedures and provide a variety of managerial implications. Results show that simultaneously determining production and warranty decisions is superior to only determining production. This study also discusses the effects of the related parameters on manufacturer's decisions and profits. The results of this study are a useful reference for managerial decision-making and administration.

Plant productivity in controlled environments

NASA Technical Reports Server (NTRS)

Salisbury, F. B.; Bugbee, B.

1988-01-01

To assess the cost and area/volume requirements of a farm in a space station or Lunar or Martian base, a few laboratories in the United States, the Soviet Union, France, and Japan are studying optimum controlled environments for the production of selected crops. Temperature, light, photoperiod, CO2, humidity, the root-zone environment, and cultivars are the primary factors being manipulated to increase yields and harvest index. Our best wheat yields on a time basis (24 g m-2 day-1 of edible biomass) are five times good field yields and twice the world record. Similar yields have been obtained in other laboratories with potatoes and lettuce; soybeans are also promising. These figures suggest that approximately 30 m2 under continuous production could support an astronaut with sufficient protein and about 2800 kcal day-1. Scientists under Iosif Gitelzon in Krasnoyarsk, Siberia, have lived in a closed system for up to 5 months, producing 80% of their own food. Thirty square meters for crops were allotted to each of the two men taking part in the experiment. A functional controlled-environment life-support system (CELSS) will require the refined application of several disciplines: controlled-environment agriculture, food preparation, waste disposal, and control-systems technology, to list only the broadest categories. It has seemed intuitively evident that ways could be found to prepare food, regenerate plant nutrients from wastes, and even control and integrate several subsystems of a CELSS. But could sufficient food be produced in the limited areas and with the limited energy that might be available? Clearly, detailed studies of food production were necessary.

Plant productivity in controlled environments.

PubMed

Salisbury, F B; Bugbee, B

1988-04-01

To assess the cost and area/volume requirements of a farm in a space station or Lunar or Martian base, a few laboratories in the United States, the Soviet Union, France, and Japan are studying optimum controlled environments for the production of selected crops. Temperature, light, photoperiod, CO2, humidity, the root-zone environment, and cultivars are the primary factors being manipulated to increase yields and harvest index. Our best wheat yields on a time basis (24 g m-2 day-1 of edible biomass) are five times good field yields and twice the world record. Similar yields have been obtained in other laboratories with potatoes and lettuce; soybeans are also promising. These figures suggest that approximately 30 m2 under continuous production could support an astronaut with sufficient protein and about 2800 kcal day-1. Scientists under Iosif Gitelzon in Krasnoyarsk, Siberia, have lived in a closed system for up to 5 months, producing 80% of their own food. Thirty square meters for crops were allotted to each of the two men taking part in the experiment. A functional controlled-environment life-support system (CELSS) will require the refined application of several disciplines: controlled-environment agriculture, food preparation, waste disposal, and control-systems technology, to list only the broadest categories. It has seemed intuitively evident that ways could be found to prepare food, regenerate plant nutrients from wastes, and even control and integrate several subsystems of a CELSS. But could sufficient food be produced in the limited areas and with the limited energy that might be available? Clearly, detailed studies of food production were necessary.

Applying State-of-the-Art Technologies to Reduce Escape Times from Fires Using Environmental Sensing, Improved Occupant Egress Guidance, and Multiple Communication Protocols

DTIC Science & Technology

2009-02-06

that could monitor sensors, evaluate environmental 4 conditions, and control visual and sound devices was conducted. The home automation products used...the prototype system. Use of off-the-shelf home automation products allowed the implementation of an egress control prototype suitable for test and

Cutleafgroundcherry (physalis angulata) density, biomass and seed production in peanut (arachis hypogaea L.) following regrowth due to inadequate control

USDA-ARS?s Scientific Manuscript database

A field experiment was conducted to evaluate herbicide and application timing on cutleaf groundcherry density, biomass, seed production, and crop yield in a peanut system. Treatments included: 1) a non-treated control; 2) hand pruning; 3) diclosulam applied preemergence (PRE) alone at 0.027 kg ai h...

An undergraduate student project to improve mechanical control of perenial nutsedges with a peanut digger in organic crop production

USDA-ARS?s Scientific Manuscript database

Perennial nutsedges are difficult to control in organic crop production systems. Tubers are generally confined to the upper portions of the soil profile and vulnerable to desiccation when on the soil surface. A peanut digger is a common implement found in the coastal plain region of the southeaste...

Aquila field: Advanced contracting strategies

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1997-04-01

Aquila oil field, in 2,800 ft of water, is in the middle of the Otranto Channel in the Mediterranean Sea, approximately 28 miles offshore southern Italy, and is subject to difficult sea and weather conditions. The many difficulties, caused mainly by water depth, requires the use of advanced technology that can be obtained only through the direct association with contractor companies. This solution safeguards the technological reliability and allows for maximum control of time and cost. The selection of a floating production, storage, and offloading (FPSO) system resulted from a feasibility study that indicated this solution was the only methodmore » that would provide economical exploitation of the Aquila field. The system includes flowlines and control lines. The ship, FPSO Agip Firenze, has been specially redesigned to manage the field development. Agip will provide the subsea production system, the Christmas tree, control system, and artificial lift.« less

Sustainable MSD prevention: management for continuous improvement between prevention and production. Ergonomic intervention in two assembly line companies.

PubMed

Caroly, S; Coutarel, F; Landry, A; Mary-Cheray, I

2010-07-01

To increase output and meet customers' needs, companies have turned to the development of production management systems: Kaizen, one piece flow, Kanban, etc. The aim of such systems is to accelerate decisions, react to environmental issues and manage various productions. In the main, this type of management system has led to the continuous improvement of production performance. Consequently, such production management systems can have unexpected negative effects on operators' health and safety. Conversely, regulation and control systems focusing on work-related risks have obliged firms to implement health and safety management systems such as OHSAS 18001. The purpose of this type of system, also based on continuous improvement, is to reduce risks, facilitate work-related activities and identify solutions in terms of equipment and tools. However, the prevention actions introduced through health and safety systems often result in other unexpected and unwanted effects on production. This paper shows how companies can improve the way they are run by taking into account both types of management system. Copyright 2010 Elsevier Ltd. All rights reserved.

49 CFR 236.923 - Task analysis and basic requirements.

Code of Federal Regulations, 2013 CFR

2013-10-01

..., INSPECTION, MAINTENANCE, AND REPAIR OF SIGNAL AND TRAIN CONTROL SYSTEMS, DEVICES, AND APPLIANCES Standards for Processor-Based Signal and Train Control Systems § 236.923 Task analysis and basic requirements..., inspection, testing, and operating tasks that must be performed on a railroad's products. This includes the...

49 CFR 236.923 - Task analysis and basic requirements.

Code of Federal Regulations, 2014 CFR

2014-10-01

..., INSPECTION, MAINTENANCE, AND REPAIR OF SIGNAL AND TRAIN CONTROL SYSTEMS, DEVICES, AND APPLIANCES Standards for Processor-Based Signal and Train Control Systems § 236.923 Task analysis and basic requirements..., inspection, testing, and operating tasks that must be performed on a railroad's products. This includes the...

49 CFR 236.923 - Task analysis and basic requirements.

Code of Federal Regulations, 2010 CFR

2010-10-01

..., INSPECTION, MAINTENANCE, AND REPAIR OF SIGNAL AND TRAIN CONTROL SYSTEMS, DEVICES, AND APPLIANCES Standards for Processor-Based Signal and Train Control Systems § 236.923 Task analysis and basic requirements..., inspection, testing, and operating tasks that must be performed on a railroad's products. This includes the...

49 CFR 236.923 - Task analysis and basic requirements.

Code of Federal Regulations, 2012 CFR

2012-10-01

..., INSPECTION, MAINTENANCE, AND REPAIR OF SIGNAL AND TRAIN CONTROL SYSTEMS, DEVICES, AND APPLIANCES Standards for Processor-Based Signal and Train Control Systems § 236.923 Task analysis and basic requirements..., inspection, testing, and operating tasks that must be performed on a railroad's products. This includes the...

Reusablility in ESOC mission control systems developments - the SMART-1 mission case

NASA Astrophysics Data System (ADS)

Pignède, Max; Davies, Kevin

2002-07-01

The European Space Operations Centre (ESOC) have a long experience in spacecraft mission control systems developments and use a large number of existing elements for the build up of control systems for new missions. The integration of such elements in a new system covers not only the direct re-use of infrastructure software but also the re-use of concepts and work methodology. Applying reusability is a major asset in ESOC's strategy, especially for low cost space missions. This paper describes re-use of existing elements in the ESOC production of the SMART-1 mission control system (S1MCS) and explores the following areas: The most significant (and major cost-saving contributors) re-used elements are the Spacecraft Control and Operations System (SCOS-2000) and the Network Control and TM/TC Router System (NCTRS) infrastructure systems. These systems are designed precisely for allowing all general mission parameters to be configured easily without any change in the software (in particular the NCTRS configuration for SMART-1 was time and cost effective). Further, large parts of the ESOC ROSETTA and INTEGRAL software systems (also SCOS-2000 based) were directly re-used, such as the on-board command schedule maintenance and modelling subsystem (OBQ), the time correlator (TCO) and the external file transfer subsystem (FTS). The INTEGRAL spacecraft database maintenance system (both the editors and configuration control mechanism) and its export facilities into the S1MCS runtime system are directly reused. A special kind of re-use concerns the ENVISAT approach to both the telemetry (TM) and telecommanding (TC) context saving in the redundant server system in order to enable smooth support of operations in case of prime server failure. In this case no software or tools can be re-used because the S1MCS is based on a much more modern technology than the ENVISAT mission control system as well as on largely differing workstations architectures but the ENVISAT validated capabilities to support hot-standby system reconfiguration and machines and data resynchronisation following failures for all mission phases make them a good candidate for re-use by newer missions. Common methods and tools for requirements production, test plan production and problem tracking which are used by most of the other ESOC missions development teams in their daily work are also re-used without any changes. Finally conclusions are drawn about reusability in perspective with the latest state of the S1MCS and about benefits to other SCOS-2000 based "client" missions. Lessons learned for ESOC space missions (whether for mission control systems currently under development or up-and-coming space missions) and also related considerations for the wider space community are made, reflecting ESOC skills and expertise in mission operations and control.

A review of the incidence and transmission of Listeria monocytogenes in ready-to-eat products in retail and food service environments.

PubMed

Lianou, Alexandra; Sofos, John N

2007-09-01

Contamination of ready-to-eat products with Listeria monocytogenes may occur at several stages before consumption. Accessibility to the public and relatively limited control interventions at retail and food service establishments (compared with the processing sector of the food industry) and the lack of a specific regulatory framework increase the likelihood of introduction of this pathogen into some foods in these establishments. This review is a compilation of available information on the incidence and transmission of L. monocytogenes through ready-to-eat products at the retail and food service level. The potential transmission of L. monocytogenes within retail and food service operations has been indicated in epidemiological investigations and by survey data. Potential sources of the organism in these operations include the environment, food handlers, and incoming raw ingredients or processed products that have become contaminated after the lethality treatment at the manufacturing facility. L. monocytogenes may be present at retail and food service establishments in various ready-to-eat products, both prepackaged and those packaged in the store, and occasionally at high concentrations. This issue dictates the need for development and application of effective control measures, and potential control approaches are discussed here. Good manufacturing practices, appropriate cleaning, sanitation and hygiene programs, and temperature control required for prevention or inhibition of growth of the pathogen to high levels are critical for control of L. monocytogenes in the retail and food service sector. A comprehensive food safety system designed to be functional in retail and food service operations and based on the philosophy of hazard analysis and critical control point systems and a series of sound prerequisite programs can provide effective control of L. monocytogenes in these environments. However, competent delivery of food safety education and training to retail and food service managers and food handlers must be in place for successful implementation of such a system.

Catalog of Audiovisual Productions. Volume 1. Army Productions

DTIC Science & Technology

1984-06-01

Anatomy and physiology of respiration, and diseases of the trespiratory system such as tuberculosis , bronchitis and pleurisy. ((Body Includes thorax...TOPES, HOING R7 TUBERCULOSIS C/02.58 TO/ERS, CONTROL TUBES, CATHODE RAY E-" TOWERS, AIRCRAFT CONTROL A 02 TUBES, ELECTRON EI"l TONING, AIRCRAFT 05 TUGS...PRACTICAL RAT CONTROL.. PATIENT WITH PULMONARY TREATMENT OF TESTICULAR RATPROOFING TUBERCULOSIS TUMORS 29812.DA MALARIA • CAUSE AND 30475.DA THERE’S

Development of Plant Control Diagnosis Technology and Increasing Its Applications

NASA Astrophysics Data System (ADS)

Kugemoto, Hidekazu; Yoshimura, Satoshi; Hashizume, Satoru; Kageyama, Takashi; Yamamoto, Toru

A plant control diagnosis technology was developed to improve the performance of plant-wide control and maintain high productivity of plants. The control performance diagnosis system containing this technology picks out the poor performance loop, analyzes the cause, and outputs the result on the Web page. Meanwhile, the PID tuning tool is used to tune extracted loops from the control performance diagnosis system. It has an advantage of tuning safely without process changes. These systems are powerful tools to do Kaizen (continuous improvement efforts) step by step, coordinating with the operator. This paper describes a practical technique regarding the diagnosis system and its industrial applications.

Contamination Control Changes to the Reusable Solid Rocket Motor Program: A Ten Year Review

NASA Technical Reports Server (NTRS)

Bushman, David M.

1998-01-01

During the post Challenger period, the National Aeronautics and Space Administration and Thiokol implemented changes to the Reusable Solid Rocket Motor (RSRM) contract to include provisions for contamination control to enhance the production environment. During the ten years since those agreements for contamination controls were made, many changes have taken place in the production facilities at Thiokol. These changes have led to the production of much higher quality shuttle solid rocket motors and improved cleanliness and safety of operations in the production facilities. The experience in contamination control over this past decade highlights the value these changes have brought to the RSRM program, and how the system can be improved to meet the challenges the program will face in the next ten years.

21 CFR 820.50 - Purchasing controls.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Purchasing controls. 820.50 Section 820.50 Food... DEVICES QUALITY SYSTEM REGULATION Purchasing Controls § 820.50 Purchasing controls. Each manufacturer... control to be exercised over the product, services, suppliers, contractors, and consultants, based on the...

21 CFR 820.50 - Purchasing controls.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Purchasing controls. 820.50 Section 820.50 Food... DEVICES QUALITY SYSTEM REGULATION Purchasing Controls § 820.50 Purchasing controls. Each manufacturer... control to be exercised over the product, services, suppliers, contractors, and consultants, based on the...

21 CFR 820.50 - Purchasing controls.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Purchasing controls. 820.50 Section 820.50 Food... DEVICES QUALITY SYSTEM REGULATION Purchasing Controls § 820.50 Purchasing controls. Each manufacturer... control to be exercised over the product, services, suppliers, contractors, and consultants, based on the...

21 CFR 820.50 - Purchasing controls.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Purchasing controls. 820.50 Section 820.50 Food... DEVICES QUALITY SYSTEM REGULATION Purchasing Controls § 820.50 Purchasing controls. Each manufacturer... control to be exercised over the product, services, suppliers, contractors, and consultants, based on the...

21 CFR 820.50 - Purchasing controls.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Purchasing controls. 820.50 Section 820.50 Food... DEVICES QUALITY SYSTEM REGULATION Purchasing Controls § 820.50 Purchasing controls. Each manufacturer... control to be exercised over the product, services, suppliers, contractors, and consultants, based on the...

Navigating sticky areas in transdermal product development.

PubMed

Strasinger, Caroline; Raney, Sam G; Tran, Doanh C; Ghosh, Priyanka; Newman, Bryan; Bashaw, Edward D; Ghosh, Tapash; Shukla, Chinmay G

2016-07-10

The benefits of transdermal delivery over the oral route to combat such issues of low bioavailability and limited controlled release opportunities are well known and have been previously discussed by many in the field (Prausnitz et al. (2004) [1]; Hadgraft and Lane (2006) [2]). However, significant challenges faced by developers as a product moves from the purely theoretical to commercial production have hampered full capitalization of the dosage forms vast benefits. While different technical aspects of transdermal system development have been discussed at various industry meetings and scientific workshops, uncertainties have persisted regarding the pharmaceutical industry's conventionally accepted approach for the development and manufacturing of transdermal systems. This review provides an overview of the challenges frequently faced and the industry's best practices for assuring the quality and performance of transdermal delivery systems and topical patches (collectively, TDS). The topics discussed are broadly divided into the evaluation of product quality and the evaluation of product performance; with the overall goal of the discussion to improve, advance and accelerate commercial development in the area of this complex controlled release dosage form. Published by Elsevier B.V.

Portable system for temperature monitoring in all phases of wine production.

PubMed

Boquete, Luciano; Cambralla, Rafael; Rodríguez-Ascariz, J M; Miguel-Jiménez, J M; Cantos-Frontela, J J; Dongil, J

2010-07-01

This paper presents a low-cost and highly versatile temperature-monitoring system applicable to all phases of wine production, from grape cultivation through to delivery of bottled wine to the end customer. Monitoring is performed by a purpose-built electronic system comprising a digital memory that stores temperature data and a ZigBee communication system that transmits it to a Control Centre for processing and display. The system has been tested under laboratory conditions and in real-world operational applications. One of the system's advantages is that it can be applied to every phase of wine production. Moreover, with minimum modification, other variables of interest (pH, humidity, etc.) could also be monitored and the system could be applied to other similar sectors, such as olive-oil production. 2010 ISA. Published by Elsevier Ltd. All rights reserved.

Development of Protection and Control Unit for Distribution Substation

NASA Astrophysics Data System (ADS)

Iguchi, Fumiaki; Hayashi, Hideyuki; Takeuchi, Motohiro; Kido, Mitsuyasu; Kobayashi, Takashi; Yanaoka, Atsushi

The Recently, electronics and IT technologies have been rapidly innovated and have been introduced to power system protection & control system to achieve high reliability, maintainability and more functionality. Concerning the distribution substation application, digital relays have been applied for more than 10 years. Because of a number of electronic devices used for it, product cost becomes higher. Also, products installed during the past high-growth period will be at the end of lifetime and will be replaced. Therefore, replacing market is expected to grow and the reduction of cost is demanded. Considering above mentioned background, second generation digital protection and control unit as a successor is designed to have following concepts. Functional integration based on advanced digital technologies, Ethernet LAN based indoor communication network, cost reduction and downsizing. Pondering above concepts, integration of protection and control function is adopted in contrary to the functional segregation applied to the previous system in order to achieve one-unit concept. Also the adoption of Ethernet LAN for inter-unit communication is objective. This report shows the development of second-generation digital relay for distribution substation, which is equipped with control function and Ethernet LAN by reducing the size of auxiliary transformer unit and the same size as previous product is realized.

Study of the ubiquitous hog farm system using wireless sensor networks for environmental monitoring and facilities control.

PubMed

Hwang, Jeonghwan; Yoe, Hyun

2010-01-01

Many hog farmers are now suffering from high pig mortality rates due to various wasting diseases and increased breeding costs, etc. It is therefore necessary for hog farms to implement systematic and scientific pig production technology to increase productivity and produce high quality pork in order to solve these problems. In this study, we describe such a technology by suggesting a ubiquitous hog farm system which applies WSN (Wireless Sensor Network) technology to the pig industry. We suggest that a WSN and CCTV (Closed-circuit television) should be installed on hog farms to collect environmental and image information which shall then help producers not only in monitoring the hog farm via the Web from outside the farm, but also facilitate the control of hog farm facilities in remote locations. In addition, facilities can be automatically controlled based on breeding environment parameters which are already set up and a SMS notice service to notify of deviations shall provide users with convenience. Hog farmers may increase production and improve pork quality through this ubiquitous hog farm system and prepare a database with information collected from environmental factors and the hog farm control devices, which is expected to provide information needed to design and implement suitable control strategies for hog farm operation.

Study of the Ubiquitous Hog Farm System Using Wireless Sensor Networks for Environmental Monitoring and Facilities Control

PubMed Central

Hwang, Jeonghwan; Yoe, Hyun

2010-01-01

Many hog farmers are now suffering from high pig mortality rates due to various wasting diseases and increased breeding costs, etc. It is therefore necessary for hog farms to implement systematic and scientific pig production technology to increase productivity and produce high quality pork in order to solve these problems. In this study, we describe such a technology by suggesting a ubiquitous hog farm system which applies WSN (Wireless Sensor Network) technology to the pig industry. We suggest that a WSN and CCTV (Closed-circuit television) should be installed on hog farms to collect environmental and image information which shall then help producers not only in monitoring the hog farm via the Web from outside the farm, but also facilitate the control of hog farm facilities in remote locations. In addition, facilities can be automatically controlled based on breeding environment parameters which are already set up and a SMS notice service to notify of deviations shall provide users with convenience. Hog farmers may increase production and improve pork quality through this ubiquitous hog farm system and prepare a database with information collected from environmental factors and the hog farm control devices, which is expected to provide information needed to design and implement suitable control strategies for hog farm operation. PMID:22163497

A System for Managing Replenishment of a Nutrient Solution Using an Electrical Conductivity Controller

NASA Technical Reports Server (NTRS)

Davis, D.; Dogan, N.; Aglan, H.; Mortley, D.; Loretan, P.

1998-01-01

Control of nutrient solution parameters is very important for the growth and development of plants grown hydroponically. Protocols involving different nutrient solution replenishment times (e.g. one-week, two-week, or two-day replenishment) provide manual periodic control of the nutrient solution's electrical conductivity (EC). Since plants take-up nutrients as they grow, manual control has a drawback in that EC is not held constant between replenishments. In an effort to correct this problem the Center for Food and Environmental Systems for Human Exploration of Space at Tuskegee University has developed a system for managing and controlling levels of EC over a plant's entire growing cycle. A prototype system is being tested on sweetpotato production using the nutrient film technique (NFT), and it is being compared to a system in which sweetpotatoes are grown using NFT with manual control. NASA has played an important role in the development of environmental control systems. They have become a forerunner in growing plants hydroponically with some control systems through the use of networked data acquisition and control using environmental growth chambers. Data acquisition systems which involve the use of real-time, calibration, set points, user panel, and graphical representation programming provide a good method of controlling nutrient solution parameters such as EC and pH [Bledsoe, 19931]. In NASA's Biomass Production Chamber (BPC) at Kennedy Space Center, control is provided by a programmable logic controller (PLC). This is an industrial controller which combines ladder computer logic which has the ability to handle various levels of electrical power. The controller controls temperature, light and other parameters that affect the plant's environment, in the BPC, the Nutrient Delivery System (NIX), a sub-system of the PLC, controls nutrient solution parameters such as EC, pH, and solution levels. When the nutrient EC measurement goes outside a preset range (120-130 mS/m) a set amount of a stock solution of nutrients is automatically added by a metering pump to bring the EC back into operating range [Fortson, 1992]. This paper describes a system developed at Tuskegee University for controlling the EC of a nutrient solution used for growing sweetpotatoes with an EC controller and a computer with LabView data acquisition and instrumentation software. It also describes the preliminary data obtained from the growth of sweetpotatoes using this prototype control system.

Autonomous benthic algal cultivator under feedback control of ecosystem metabolism

USDA-ARS?s Scientific Manuscript database

An autonomous and internally-controlled techno-ecological hybrid was developed that controls primary production of algae in a laboratory-scale cultivator. The technoecosystem is based on an algal turf scrubber (ATS) system that combines engineered feedback control programming with internal feedback...

Fuzzy logic controllers: A knowledge-based system perspective

NASA Technical Reports Server (NTRS)

Bonissone, Piero P.

1993-01-01

Over the last few years we have seen an increasing number of applications of Fuzzy Logic Controllers. These applications range from the development of auto-focus cameras, to the control of subway trains, cranes, automobile subsystems (automatic transmissions), domestic appliances, and various consumer electronic products. In summary, we consider a Fuzzy Logic Controller to be a high level language with its local semantics, interpreter, and compiler, which enables us to quickly synthesize non-linear controllers for dynamic systems.

Effect of static magnetic field on the oxygen production of Scenedesmus obliquus cultivated in municipal wastewater.

PubMed

Tu, Renjie; Jin, Wenbiao; Xi, Tingting; Yang, Qian; Han, Song-Fang; Abomohra, Abd El-Fatah

2015-12-01

Algal-bacterial symbiotic system, with biological synergism of physiological functions of both algae and bacteria, has been proposed for cultivation of microalgae in municipal wastewater for biomass production and wastewater treatment. The algal-bacterial symbiotic system can enhance dissolved oxygen production which enhances bacterial growth and catabolism of pollutants in wastewater. Therefore, the oxygen production efficiency of microalgae in algal-bacterial systems is considered as the key factor influencing the wastewater treatment efficiency. In the present study, we have proposed a novel approach which uses static magnetic field to enhance algal growth and oxygen production rate with low operational cost and non-toxic secondary pollution. The performance of oxygen production with the magnetic field was evaluated using Scenedesmus obliquus grown in municipal wastewater and was calculated based on the change in dissolved oxygen concentration. Results indicated that magnetic treatment stimulates both algal growth and oxygen production. Application of 1000 GS of magnetic field once at logarithmic growth phase for 0.5 h increased the chlorophyll-a content by 11.5% over the control after 6 days of growth. In addition, magnetization enhanced the oxygen production rate by 24.6% over the control. Results of the study confirmed that application of a proper magnetic field could reduce the energy consumption required for aeration during the degradation of organic matter in municipal wastewater in algal-bacterial symbiotic systems. Copyright © 2015 Elsevier Ltd. All rights reserved.

Robust modular product family design

NASA Astrophysics Data System (ADS)

Jiang, Lan; Allada, Venkat

2001-10-01

This paper presents a modified Taguchi methodology to improve the robustness of modular product families against changes in customer requirements. The general research questions posed in this paper are: (1) How to effectively design a product family (PF) that is robust enough to accommodate future customer requirements. (2) How far into the future should designers look to design a robust product family? An example of a simplified vacuum product family is used to illustrate our methodology. In the example, customer requirements are selected as signal factors; future changes of customer requirements are selected as noise factors; an index called quality characteristic (QC) is set to evaluate the product vacuum family; and the module instance matrix (M) is selected as control factor. Initially a relation between the objective function (QC) and the control factor (M) is established, and then the feasible M space is systemically explored using a simplex method to determine the optimum M and the corresponding QC values. Next, various noise levels at different time points are introduced into the system. For each noise level, the optimal values of M and QC are computed and plotted on a QC-chart. The tunable time period of the control factor (the module matrix, M) is computed using the QC-chart. The tunable time period represents the maximum time for which a given control factor can be used to satisfy current and future customer needs. Finally, a robustness index is used to break up the tunable time period into suitable time periods that designers should consider while designing product families.

[Modeling developmental aspects of sensorimotor control of speech production].

PubMed

Kröger, B J; Birkholz, P; Neuschaefer-Rube, C

2007-05-01

Detailed knowledge of the neurophysiology of speech acquisition is important for understanding the developmental aspects of speech perception and production and for understanding developmental disorders of speech perception and production. A computer implemented neural model of sensorimotor control of speech production was developed. The model is capable of demonstrating the neural functions of different cortical areas during speech production in detail. (i) Two sensory and two motor maps or neural representations and the appertaining neural mappings or projections establish the sensorimotor feedback control system. These maps and mappings are already formed and trained during the prelinguistic phase of speech acquisition. (ii) The feedforward sensorimotor control system comprises the lexical map (representations of sounds, syllables, and words of the first language) and the mappings from lexical to sensory and to motor maps. The training of the appertaining mappings form the linguistic phase of speech acquisition. (iii) Three prelinguistic learning phases--i. e. silent mouthing, quasi stationary vocalic articulation, and realisation of articulatory protogestures--can be defined on the basis of our simulation studies using the computational neural model. These learning phases can be associated with temporal phases of prelinguistic speech acquisition obtained from natural data. The neural model illuminates the detailed function of specific cortical areas during speech production. In particular it can be shown that developmental disorders of speech production may result from a delayed or incorrect process within one of the prelinguistic learning phases defined by the neural model.

Safety Analysis of Soybean Processing for Advanced Life Support

NASA Technical Reports Server (NTRS)

Hentges, Dawn L.

1999-01-01

Soybeans (cv. Hoyt) is one of the crops planned for food production within the Advanced Life Support System Integration Testbed (ALSSIT), a proposed habitat simulation for long duration lunar/Mars missions. Soybeans may be processed into a variety of food products, including soymilk, tofu, and tempeh. Due to the closed environmental system and importance of crew health maintenance, food safety is a primary concern on long duration space missions. Identification of the food safety hazards and critical control points associated with the closed ALSSIT system is essential for the development of safe food processing techniques and equipment. A Hazard Analysis Critical Control Point (HACCP) model was developed to reflect proposed production and processing protocols for ALSSIT soybeans. Soybean processing was placed in the type III risk category. During the processing of ALSSIT-grown soybeans, critical control points were identified to control microbiological hazards, particularly mycotoxins, and chemical hazards from antinutrients. Critical limits were suggested at each CCP. Food safety recommendations regarding the hazards and risks associated with growing, harvesting, and processing soybeans; biomass management; and use of multifunctional equipment were made in consideration of the limitations and restraints of the closed ALSSIT.

The good laboratory practice and good clinical practice requirements for the production of radiopharmaceuticals in clinical research.

PubMed

De Vos, Filip J; De Decker, Mario; Dierckx, Rudi A

2005-07-01

Radiopharmaceuticals account for more than 95% of the group of sterile pharmaceutical products and should therefore be handled and produced with care. Since the introduction of the European directive, all pharmaceuticals used in clinical studies must be prepared under good manufacturing practice (GMP) conditions. This review aims to give an overview of the basic principles and guidelines for the preparation of radiopharmaceuticals. Special attention is given to the production area environment and personnel, the two basic requirements for GMP productions. Especially for the production area, two philosophies have to be combined: the cascade system of over-pressure for the production of pharmaceuticals and the under pressure system for the manufacturing of radioisotopes. Personnel should be selected based on education and regularly given special training for the handling of radioactive material. Compared to pharmaceuticals, radiopharmaceuticals have their own labels, taking into account their specific nature. Besides the standard quality control, other items for quality control of radiopharmaceuticals are also discussed in this article.

Mechatronical system for testing small diameter drills

NASA Astrophysics Data System (ADS)

Vekteris, Vladas; Jurevichius, Mindaugas; Daktariunas, Algis

2008-08-01

This paper describes a technique and mechatronical system for testing drills of a small diameter at different stages of production. The goal is to realize a system for drill testing which automatically increases the load applied to a drill under testing conditions and measure the drill's breaking torsion moment and deflection angle before a break occurs. The system's apparatus part and algorithms for the control of actuators and data acquisition from sensors are explained in the article. Also, a testing technique was applied in theoretical investigations to define the stress concentrations in dangerous places of the drill. The proposed technique and system have been verified by testing the drills of a small diameter at different stages of production—after thermal, mechanical treatment, and for quality control of the finished product.

MAPGEN CARTOGRAPHIC SYSTEM.

USGS Publications Warehouse

Evenden, Gerald I.; ,

1986-01-01

MAPGEN is a software system that facilitates production of cartographic displays in the research and production environment. The system generates a set of metagraphic overlays of application-defined geographical information that can be aggregated in any combination for display without reprocessing the original data. An overview of the control files, available cartographic projections, graphic attributes, overlay generator and ancillary support programs, and the device-independent graphic subsystem are presented, along with examples of usage. System transportability and associated host hardware and operating system requirements are also addressed.

In-line height profiling metrology sensor for zero defect production control

NASA Astrophysics Data System (ADS)

Snel, Rob; Winters, Jasper; Liebig, Thomas; Jonker, Wouter

2017-06-01

Contemporary production systems of mechanical precision parts show challenges as increased complexity, tolerances shrinking to sub-microns and yield losses that must be mastered to the extreme. More advanced automation and process control is required to accomplish this task. Often a solution based on feedforward/feedback control is chosen requiring innovative and more advanced in line metrology. This article concentrates first on the context of in line metrology for process control and then on the development of a specific in line height profiling sensor. The novel sensor technology is based on full field time domain white light interferometry which is well know from the quality lab. The novel metrology system is to be mounted close to the production equipment, as required to minimize time delay in the control loop, and is thereby fully exposed to vibrations. This sensor is innovated to perform in line with an orders of magnitude faster throughput than laboratory instruments; it's robust to withstand the rigors of workshops and has a height resolution that is in the nanometer range.

Multi-Disciplinary Design Optimization Using WAVE

NASA Technical Reports Server (NTRS)

Irwin, Keith

2000-01-01

The current preliminary design tools lack the product performance, quality and cost prediction fidelity required to design Six Sigma products. They are also frequently incompatible with the tools used in detailed design, leading to a great deal of rework and lost or discarded data in the transition from preliminary to detailed design. Thus, enhanced preliminary design tools are needed in order to produce adequate financial returns to the business. To achieve this goal, GEAE has focused on building the preliminary design system around the same geometric 3D solid model that will be used in detailed design. With this approach, the preliminary designer will no longer convert a flowpath sketch into an engine cross section but rather, automatically create 3D solid geometry for structural integrity, life, weight, cost, complexity, producibility, and maintainability assessments. Likewise, both the preliminary design and the detailed design can benefit from the use of the same preliminary part sizing routines. The design analysis tools will also be integrated with the 3D solid model to eliminate manual transfer of data between programs. GEAE has aggressively pursued the computerized control of engineering knowledge for many years. Through its study and validation of 3D CAD programs and processes, GEAE concluded that total system control was not feasible at that time. Prior CAD tools focused exclusively on detail part geometry and Knowledge Based Engineering systems concentrated on rules input and data output. A system was needed to bridge the gap between the two to capture the total system. With the introduction of WAVE Engineering from UGS, the possibilities of an engineering system control device began to formulate. GEAE decided to investigate the new WAVE functionality to accomplish this task. NASA joined GEAE in funding this validation project through Task Order No. 1. With the validation project complete, the second phase under Task Order No. 2 was established to develop an associative control structure (framework) in the UG WAVE environment enabling multi-disciplinary design of turbine propulsion systems. The capabilities of WAVE were evaluated to assess its use as a rapid optimization and productivity tool. This project also identified future WAVE product enhancements that will make the tool still more beneficial for product development.

Dynamic analysis, circuit implementation and passive control of a novel four-dimensional chaotic system with multiscroll attractor and multiple coexisting attractors

NASA Astrophysics Data System (ADS)

Lai, Bang-Cheng; He, Jian-Jun

2018-03-01

In this paper, we construct a novel 4D autonomous chaotic system with four cross-product nonlinear terms and five equilibria. The multiple coexisting attractors and the multiscroll attractor of the system are numerically investigated. Research results show that the system has various types of multiple attractors, including three strange attractors with a limit cycle, three limit cycles, two strange attractors with a pair of limit cycles, two coexisting strange attractors. By using the passive control theory, a controller is designed for controlling the chaos of the system. Both analytical and numerical studies verify that the designed controller can suppress chaotic motion and stabilise the system at the origin. Moreover, an electronic circuit is presented for implementing the chaotic system.

The reactive bed plasma system for contamination control

NASA Technical Reports Server (NTRS)

Birmingham, Joseph G.; Moore, Robert R.; Perry, Tony R.

1990-01-01

The contamination control capabilities of the Reactive Bed Plasma (RBP) system is described by delineating the results of toxic chemical composition studies, aerosol filtration work, and other testing. The RBP system has demonstrated its capabilities to decompose toxic materials and process hazardous aerosols. The post-treatment requirements for the reaction products have possible solutions. Although additional work is required to meet NASA requirements, the RBP may be able to meet contamination control problems aboard the Space Station.

Comparative analyses of different variants of standard ground for automatic control systems of technical processes of oil and gas production

NASA Astrophysics Data System (ADS)

Gromakov, E. I.; Gazizov, A. T.; Lukin, V. P.; Chimrov, A. V.

2017-01-01

The paper analyses efficiency (interference resistance) of standard TT, TN, IT networks in control links of automatic control systems (ACS) of technical processes (TP) of oil and gas production. Electromagnetic compatibility (EMC) is a standard term used to describe the interference in grounding circuits. Improved EMC of ACS TP can significantly reduce risks and costs of malfunction of equipment that could have serious consequences. It has been proved that an IT network is the best type of grounds for protection of ACS TP in real life conditions. It allows reducing the interference down to the level that is stated in standards of oil and gas companies.

When the firm prevents the crash: Avoiding market collapse with partial control.

PubMed

Levi, Asaf; Sabuco, Juan; A F Sanjuán, Miguel

2017-01-01

Market collapse is one of the most dramatic events in economics. Such a catastrophic event can emerge from the nonlinear interactions between the economic agents at the micro level of the economy. Transient chaos might be a good description of how a collapsing market behaves. In this work, we apply a new control method, the partial control method, with the goal of avoiding this disastrous event. Contrary to common control methods that try to influence the system from the outside, here the market is controlled from the bottom up by one of the most basic components of the market-the firm. This is the first time that the partial control method is applied on a strictly economical system in which we also introduce external disturbances. We show how the firm is capable of controlling the system avoiding the collapse by only adjusting the selling price of the product or the quantity of production in accordance to the market circumstances. Additionally, we demonstrate how a firm with a large market share is capable of influencing the demand achieving price stability across the retail and wholesale markets. Furthermore, we prove that the control applied in both cases is much smaller than the external disturbances.

The research of laser marking control technology

NASA Astrophysics Data System (ADS)

Zhang, Qiue; Zhang, Rong

2009-08-01

In the area of Laser marking, the general control method is insert control card to computer's mother board, it can not support hot swap, it is difficult to assemble or it. Moreover, the one marking system must to equip one computer. In the system marking, the computer can not to do the other things except to transmit marking digital information. Otherwise it can affect marking precision. Based on traditional control methods existed some problems, introduced marking graphic editing and digital processing by the computer finish, high-speed digital signal processor (DSP) control marking the whole process. The laser marking controller is mainly contain DSP2812, digital memorizer, DAC (digital analog converting) transform unit circuit, USB interface control circuit, man-machine interface circuit, and other logic control circuit. Download the marking information which is processed by computer to U disk, DSP read the information by USB interface on time, then processing it, adopt the DSP inter timer control the marking time sequence, output the scanner control signal by D/A parts. Apply the technology can realize marking offline, thereby reduce the product cost, increase the product efficiency. The system have good effect in actual unit markings, the marking speed is more quickly than PCI control card to 20 percent. It has application value in practicality.

A tensor approach to modeling of nonhomogeneous nonlinear systems

NASA Technical Reports Server (NTRS)

Yurkovich, S.; Sain, M.

1980-01-01

Model following control methodology plays a key role in numerous application areas. Cases in point include flight control systems and gas turbine engine control systems. Typical uses of such a design strategy involve the determination of nonlinear models which generate requested control and response trajectories for various commands. Linear multivariable techniques provide trim about these motions; and protection logic is added to secure the hardware from excursions beyond the specification range. This paper reports upon experience in developing a general class of such nonlinear models based upon the idea of the algebraic tensor product.

Development of integrated programs for Aerospace-vehicle Design (IPAD): Product program management systems

NASA Technical Reports Server (NTRS)

Isenberg, J. M.; Southall, J. W.

1979-01-01

The Integrated Programs for Aerospace Vehicle Design (IPAD) is a computing system to support company-wide design information processing. This document presents a brief description of the management system used to direct and control a product-oriented program. This document, together with the reference design process (CR 2981) and the manufacture interactions with the design process (CR 2982), comprises the reference information that forms the basis for specifying IPAD system requirements.

Increased Reliability of Gas Turbine Components by Robust Coatings Manufacturing

NASA Astrophysics Data System (ADS)

Sharma, A.; Dudykevych, T.; Sansom, D.; Subramanian, R.

2017-08-01

The expanding operational windows of the advanced gas turbine components demand increasing performance capability from protective coating systems. This demand has led to the development of novel multi-functional, multi-materials coating system architectures over the last years. In addition, the increasing dependency of components exposed to extreme environment on protective coatings results in more severe penalties, in case of a coating system failure. This emphasizes that reliability and consistency of protective coating systems are equally important to their superior performance. By means of examples, this paper describes the effects of scatter in the material properties resulting from manufacturing variations on coating life predictions. A strong foundation in process-property-performance correlations as well as regular monitoring and control of the coating process is essential for robust and well-controlled coating process. Proprietary and/or commercially available diagnostic tools can help in achieving these goals, but their usage in industrial setting is still limited. Various key contributors to process variability are briefly discussed along with the limitations of existing process and product control methods. Other aspects that are important for product reliability and consistency in serial manufacturing as well as advanced testing methodologies to simplify and enhance product inspection and improve objectivity are briefly described.

Peripheral mechanisms for vocal production in birds - differences and similarities to human speech and singing.

PubMed

Riede, Tobias; Goller, Franz

2010-10-01

Song production in songbirds is a model system for studying learned vocal behavior. As in humans, bird phonation involves three main motor systems (respiration, vocal organ and vocal tract). The avian respiratory mechanism uses pressure regulation in air sacs to ventilate a rigid lung. In songbirds sound is generated with two independently controlled sound sources, which reside in a uniquely avian vocal organ, the syrinx. However, the physical sound generation mechanism in the syrinx shows strong analogies to that in the human larynx, such that both can be characterized as myoelastic-aerodynamic sound sources. Similarities include active adduction and abduction, oscillating tissue masses which modulate flow rate through the organ and a layered structure of the oscillating tissue masses giving rise to complex viscoelastic properties. Differences in the functional morphology of the sound producing system between birds and humans require specific motor control patterns. The songbird vocal apparatus is adapted for high speed, suggesting that temporal patterns and fast modulation of sound features are important in acoustic communication. Rapid respiratory patterns determine the coarse temporal structure of song and maintain gas exchange even during very long songs. The respiratory system also contributes to the fine control of airflow. Muscular control of the vocal organ regulates airflow and acoustic features. The upper vocal tract of birds filters the sounds generated in the syrinx, and filter properties are actively adjusted. Nonlinear source-filter interactions may also play a role. The unique morphology and biomechanical system for sound production in birds presents an interesting model for exploring parallels in control mechanisms that give rise to highly convergent physical patterns of sound generation. More comparative work should provide a rich source for our understanding of the evolution of complex sound producing systems. Copyright © 2009 Elsevier Inc. All rights reserved.

Effects of climatic control on tomato yield and nutritional quality in Mediterranean screenhouse.

PubMed

Leyva, Rocío; Constán-Aguilar, Christian; Blasco, Begoña; Sánchez-Rodríguez, Eva; Romero, Luis; Soriano, Teresa; Ruíz, Juan M

2014-01-15

The quality of vegetables for fresh consumption is a complex issue. In this study the yield and quality of cherry tomato fruits were assessed under different environmental control conditions, namely in a screenhouse (S), in a screenhouse equipped with a fogging system (SF) and in a screenhouse with complements such as plastic sheeting to maintain the microclimate created by the fogging system (SFS), as well as under open field (OF) cultivation. Levels of vitamin C, carotenoids (lycopene, β-carotene and lutein), phenolic compounds (flavonoids and phenolic acids), sugars (fructose, glucose and sucrose), organic acids (citric acid and malic acid) and flavour indices were measured. The aim of the study was to determine how different environmental control technologies could influence production and quality traits in tomato cherry fruits cultivated in a Mediterranean area. The results showed that the fogging system treatment's decline in maximum vapour pressure deficit (by 0.7 kPa compared with OF cultivation), increase in mean fruit weight (by about 4 g per fruit) and low radiation and temperature values may exert a positive effect on lycopene accumulation. For the production and nutritional parameters measured, it is postulated that the fogging system treatment offers a better balance between production and nutritional quality. This treatment proved to be best in terms of productivity, vitamin C and lycopene contents and antioxidant capacity. © 2013 Society of Chemical Industry.

Statistical Methods in Assembly Quality Management of Multi-Element Products on Automatic Rotor Lines

NASA Astrophysics Data System (ADS)

Pries, V. V.; Proskuriakov, N. E.

2018-04-01

To control the assembly quality of multi-element mass-produced products on automatic rotor lines, control methods with operational feedback are required. However, due to possible failures in the operation of the devices and systems of automatic rotor line, there is always a real probability of getting defective (incomplete) products into the output process stream. Therefore, a continuous sampling control of the products completeness, based on the use of statistical methods, remains an important element in managing the quality of assembly of multi-element mass products on automatic rotor lines. The feature of continuous sampling control of the multi-element products completeness in the assembly process is its breaking sort, which excludes the possibility of returning component parts after sampling control to the process stream and leads to a decrease in the actual productivity of the assembly equipment. Therefore, the use of statistical procedures for continuous sampling control of the multi-element products completeness when assembled on automatic rotor lines requires the use of such sampling plans that ensure a minimum size of control samples. Comparison of the values of the limit of the average output defect level for the continuous sampling plan (CSP) and for the automated continuous sampling plan (ACSP) shows the possibility of providing lower limit values for the average output defects level using the ACSP-1. Also, the average sample size when using the ACSP-1 plan is less than when using the CSP-1 plan. Thus, the application of statistical methods in the assembly quality management of multi-element products on automatic rotor lines, involving the use of proposed plans and methods for continuous selective control, will allow to automating sampling control procedures and the required level of quality of assembled products while minimizing sample size.

In-line manufacture of carbon nanotubes

DOEpatents

Brambilla, Nicol Michele; Signorelli, Riccardo; Martini, Fabrizio; Corripio Luna, Oscar Enrique

2015-04-28

Mass production of carbon nanotubes (CNT) are facilitated by methods and apparatus disclosed herein. Advantageously, the methods and apparatus make use of a single production unit, and therefore provide for uninterrupted progress in a fabrication process. Embodiments of control systems for a variety of CNT production apparatus are included.

50 CFR 260.97 - Conditions for providing fishery products inspection service at official establishments.

Code of Federal Regulations, 2010 CFR

2010-10-01

... CERTIFICATION Inspection and Certification of Establishments and Fishery Products for Human Consumption... control systems and cooperation. The inspection effort requirement may be reevaluated when the contracting...; or (2) For production errors, such as processing temperatures, length of process, or misbranding of...

50 CFR 260.97 - Conditions for providing fishery products inspection service at official establishments.

Code of Federal Regulations, 2011 CFR

2011-10-01

... CERTIFICATION Inspection and Certification of Establishments and Fishery Products for Human Consumption... control systems and cooperation. The inspection effort requirement may be reevaluated when the contracting...; or (2) For production errors, such as processing temperatures, length of process, or misbranding of...

Performance of Control System Using Microcontroller for Sea Water Circulation

NASA Astrophysics Data System (ADS)

Indriani, A.; Witanto, Y.; Pratama, A. S.; Supriyadi; Hendra; Tanjung, A.

2018-02-01

Now a day control system is very important rule for any process. Control system have been used in the automatic system. Automatic system can be seen in the industrial filed, mechanical field, electrical field and etc. In industrial and mechanical field, control system are used for control of motion component such as motor, conveyor, machine, control of process made of product, control of system and soon. In electrical field, control system can met for control of electrical system as equipment or part electrical like fan, rice cooker, refrigerator, air conditioner and etc. Control system are used for control of temperature and circulation gas, air and water. Control system of temperature and circulation of water also can be used for fisher community. Control system can be create by using microcontroller, PLC and other automatic program [1][2]. In this paper we will focus on the close loop system by using microcontroller Arduino Mega to control of temperature and circulation of sea water for fisher community. Performance control system is influenced by control equipment, sensor sensitivity, test condition, environment and others. The temperature sensor is measured using the DS18S20 and the sea water clarity sensor for circulation indicator with turbidity sensor. From the test results indicated that this control system can circulate sea water and maintain the temperature and clarity of seawater in a short time.

Optima XE Single Wafer High Energy Ion Implanter

DOE Office of Scientific and Technical Information (OSTI.GOV)

Satoh, Shu; Ferrara, Joseph; Bell, Edward

2008-11-03

The Optima XE is the first production worthy single wafer high energy implanter. The new system combines a state-of-art single wafer endstation capable of throughputs in excess of 400 wafers/hour with a production-proven RF linear accelerator technology. Axcelis has been evolving and refining RF Linac technology since the introduction of the NV1000 in 1986. The Optima XE provides production worthy beam currents up to energies of 1.2 MeV for P{sup +}, 2.9 MeV for P{sup ++}, and 1.5 MeV for B{sup +}. Energies as low as 10 keV and tilt angles as high as 45 degrees are also available., allowingmore » the implanter to be used for a wide variety of traditional medium current implants to ensure high equipment utilization. The single wafer endstation provides precise implant angle control across wafer and wafer to wafer. In addition, Optima XE's unique dose control system allows compensation of photoresist outgassing effects without relying on traditional pressure-based methods. We describe the specific features, angle control and dosimetry of the Optima XE and their applications in addressing the ever-tightening demands for more precise process controls and higher productivity.« less

New controls spark boiler efficiency

DOE Office of Scientific and Technical Information (OSTI.GOV)

Engels, T.

1993-09-01

Monsanto's NutraSweet plant in University Park, IL, produces aspartame, the patented NutraSweet artificial sweetener product. Until recently, boiler control was managed by a '60s-era Fireye jackshaft system in which air and natural gas were mechanically linked with an offset to compensate for oxygen trim. The interlocking devices on the Fireye system were becoming obsolete, and the boiler needed a new front end retrofitted for low emissions. In order to improve boiler control efficiency, we decided to modernize and automate the entire boiler control system. We replaced the original jackshaft system, and installed a Gordon-Piet burner system, including gas valves, airmore » dampers, blowers, and burner. The upgrade challenges included developing a control strategy and selecting and implementing a process control system. Since our plant has standardized on the PROVOX process management information system from Fisher Controls (now Fisher-Rosemount Systems) to support most of our process, it was a natural and logical choice for boiler controls as well. 2 figs.« less

Production system with process quality control: modelling and application

NASA Astrophysics Data System (ADS)

Tsou, Jia-Chi

2010-07-01

Over the past decade, there has been a great deal of research dedicated to the study of quality and the economics of production. In this article, we develop a dynamic model which is based on the hypothesis of a traditional economic production quantity model. Taguchi's cost of poor quality is used to evaluate the cost of poor quality in the dynamic production system. A practical case from the automotive industry, which uses the Six-sigma DMAIC methodology, is discussed to verify the proposed model. This study shows that there is an optimal value of quality investment to make the production system reach a reasonable quality level and minimise the production cost. Based on our model, the management can adjust its investment in quality improvement to generate considerable financial return.

Possible Computer Vision Systems and Automated or Computer-Aided Edging and Trimming

Treesearch

Philip A. Araman

1990-01-01

This paper discusses research which is underway to help our industry reduce costs, increase product volume and value recovery, and market more accurately graded and described products. The research is part of a team effort to help the hardwood sawmill industry automate with computer vision systems, and computer-aided or computer controlled processing. This paper...

[Investigation on production process quality control of traditional Chinese medicine--Banlangen granule as an example].

PubMed

Tan, Manrong; Yan, Dan; Qiu, Lingling; Chen, Longhu; Yan, Yan; Jin, Cheng; Li, Hanbing; Xiao, Xiaohe

2012-04-01

For the quality management system of herbal medicines, intermediate and finished products it exists the " short board" effect of methodologies. Based on the concept of process control, new strategies and new methods of the production process quality control had been established with the consideration of the actual production of traditional Chinese medicine an the characteristics of Chinese medicine. Taking Banlangen granule as a practice example, which was effective and widespread application, character identification, determination of index components, chemical fingerprint and biometrics technology were sequentially used respectively to assess the quality of Banlangen herbal medicines, intermediate (water extraction and alcohol precipitation) and finished product. With the transfer rate of chemical information and biological potency as indicators, the effectiveness and transmission of the above different assessments and control methods had been researched. And ultimately, the process quality control methods of Banlangen granule, which were based on chemical composition analysis-biometric analysis, had been set up. It can not only validly solute the current status that there were many manufacturers varying quality of Banlangen granule, but also ensure and enhance its clinical efficacy. Furthermore it provided a foundation for the construction of the quality control of traditional Chinese medicine production process.

Optical system design, analysis, and production; Proceedings of the Meeting, Geneva, Switzerland, April 19-22, 1983

NASA Astrophysics Data System (ADS)

Rogers, P. J.; Fischer, R. E.

1983-01-01

Topics considered include: optical system requirements, analysis, and system engineering; optical system design using microcomputers and minicomputers; optical design theory and computer programs; optical design methods and computer programs; optical design methods and philosophy; unconventional optical design; diffractive and gradient index optical system design; optical production and system integration; and optical systems engineering. Particular attention is given to: stray light control as an integral part of optical design; current and future directions of lens design software; thin-film technology in the design and production of optical systems; aspherical lenses in optical scanning systems; the application of volume phase holograms to avionic displays; the effect of lens defects on thermal imager performance; and a wide angle zoom for the Space Shuttle.

Advanced Control Systems for Aircraft Powerplants

DTIC Science & Technology

1980-02-01

production of high- integrity software. 1.0 INTRODUCTION Work on full-authority digital control for gas turbines was started at Rolls- Royce Limited... INTRODUCTION In order to fully understand the operation of the Secondary Power System Control Unit - abbreviated SPSCU - we must first take a close look at...Only Memory EPROM -- Erasable Read Only Memory PLA -- Power Lever Angle LVDT -- Linear Variable Differential Transformer INTRODUCTION Preliminary design

Magnetic control systems for large spacecraft with applications to space telescope

NASA Technical Reports Server (NTRS)

Dougherty, H.; Machnick, J.; Nakashima, A.; Henry, J.; Tompetrini, K.

1981-01-01

Magnetic control systems for large space vehicles offer the advantage of a simple, reliable, low cost augmentation to the primary control system. When used for momentum management, a magnetic torque source offers a long life and noncontaminant environment when compared to a mass expulsion torque source. These qualities make such systems suitable for employment with the Space Telescope, which is a long life, high performance vehicle with optics and scientific instruments which would be degraded by contamination due to mass expulsion products. The various applications of magnetic systems on the Space Telescope are considered. The future trend in magnetic control of large space vehicles lies in providing a known three axis reference for backup operations, such as recovery of the primary control mode.

System-wide power management control via clock distribution network

DOEpatents

Coteus, Paul W.; Gara, Alan; Gooding, Thomas M.; Haring, Rudolf A.; Kopcsay, Gerard V.; Liebsch, Thomas A.; Reed, Don D.

2015-05-19

An apparatus, method and computer program product for automatically controlling power dissipation of a parallel computing system that includes a plurality of processors. A computing device issues a command to the parallel computing system. A clock pulse-width modulator encodes the command in a system clock signal to be distributed to the plurality of processors. The plurality of processors in the parallel computing system receive the system clock signal including the encoded command, and adjusts power dissipation according to the encoded command.

In vitro meat: A future animal-free harvest.

PubMed

Bhat, Zuhaib Fayaz; Kumar, Sunil; Bhat, Hina Fayaz

2017-03-04

In vitro meat production is a novel idea of producing meat without involving animals with the help of tissue engineering techniques. This biofabrication of complex living products by using various bioengineering techniques is a potential solution to reduce the ill effects of current meat production systems and can dramatically transform traditional animal-based agriculture by inventing "animal-free" meat and meat products. Nutrition-related diseases, food-borne illnesses, resource use and pollution, and use of farm animals are some serious consequences associated with conventional meat production methods. This new way of animal-free meat production may offer health and environmental advantages by reducing environmental pollution and resource use associated with current meat production systems and will also ensure sustainable production of designer, chemically safe, and disease-free meat as the conditions in an in vitro meat production system are controllable and manipulatable. Theoretically, this system is believed to be efficient enough to supply the global demand for meat; however, establishment of a sustainable in vitro meat production would face considerably greater technical challenges and a great deal of research is still needed to establish this animal-free meat culturing system on an industrial scale.

Maximizing the productivity of the microalgae Scenedesmus AMDD cultivated in a continuous photobioreactor using an online flow rate control.

PubMed

McGinn, Patrick J; MacQuarrie, Scott P; Choi, Jerome; Tartakovsky, Boris

2017-01-01

In this study, production of the microalga Scenedesmus AMDD in a 300 L continuous flow photobioreactor was maximized using an online flow (dilution rate) control algorithm. To enable online control, biomass concentration was estimated in real time by measuring chlorophyll-related culture fluorescence. A simple microalgae growth model was developed and used to solve the optimization problem aimed at maximizing the photobioreactor productivity. When optimally controlled, Scenedesmus AMDD culture demonstrated an average volumetric biomass productivity of 0.11 g L -1  d -1 over a 25 day cultivation period, equivalent to a 70 % performance improvement compared to the same photobioreactor operated as a turbidostat. The proposed approach for optimizing photobioreactor flow can be adapted to a broad range of microalgae cultivation systems.

Distributed communications and control network for robotic mining

NASA Technical Reports Server (NTRS)

Schiffbauer, William H.

1989-01-01

The application of robotics to coal mining machines is one approach pursued to increase productivity while providing enhanced safety for the coal miner. Toward that end, a network composed of microcontrollers, computers, expert systems, real time operating systems, and a variety of program languages are being integrated that will act as the backbone for intelligent machine operation. Actual mining machines, including a few customized ones, have been given telerobotic semiautonomous capabilities by applying the described network. Control devices, intelligent sensors and computers onboard these machines are showing promise of achieving improved mining productivity and safety benefits. Current research using these machines involves navigation, multiple machine interaction, machine diagnostics, mineral detection, and graphical machine representation. Guidance sensors and systems employed include: sonar, laser rangers, gyroscopes, magnetometers, clinometers, and accelerometers. Information on the network of hardware/software and its implementation on mining machines are presented. Anticipated coal production operations using the network are discussed. A parallelism is also drawn between the direction of present day underground coal mining research to how the lunar soil (regolith) may be mined. A conceptual lunar mining operation that employs a distributed communication and control network is detailed.

Research-to-operations (R2O) for the Space Environmental Effects Fusion System (SEEFS) system-impact products

NASA Astrophysics Data System (ADS)

Quigley, Stephen

The Space Vehicles Directorate of the Air Force Research Laboratory (AFRL/RVBX) and the Space Environment Branch of the Space and Missile Systems Center (SMC SLG/WMLE) have combined efforts to design, develop, test, implement, and validate numerical and graphical products for Air Force Space Command's (AFSPC) Space Environmental Effects Fusion System (SEEFS). These products are generated to analyze, specify, and forecast the effects of the near-earth space environment on Department of Defense weapons, navigation, communications, and surveillance systems. Jointly developed projects that have been completed as prototypes and are undergoing development for real-time operations include a SEEFS architecture and database, five system-impact products, and a high-level decision aid product. This first round of SEEFS products includes the Solar Radio Burst Effects (SoRBE) on radar and satellite communications, Radar Auroral Clutter (RAC), Scintillation Effects on radar and satellite communications (RadScint and SatScint), and Satellite Surface and Deep Charge/Discharge (Char/D) products. This presentation will provide overviews of the current system impact products, along with plans and potentials for future products expected for the SEEFS program. The overviews will include information on applicable research-to-operations (R2O) issues, to include input data coverage and quality control, output confidence levels, modeling standards, and validation efforts.

Integration, design, and construction of a CELSS breadboard facility for bioregenerative life support system research

NASA Technical Reports Server (NTRS)

Prince, R.; Knott, W.; Buchanan, Paul

1987-01-01

Design criteria for the Biomass Production Chamber (BPC), preliminary operating procedures, and requirements for the future development of the Controlled Ecological Life Support System (CELSS) are discussed. CELSS, which uses a bioregenerative system, includes the following three major units: (1) a biomass production component to grow plants under controlled conditions; (2) food processing components to derive maximum edible content from all plant parts; and (3) waste management components to recover and recycle all solids, liquids, and gases necessary to support life. The current status of the CELSS breadboard facility is reviewed; a block diagram of a simplified version of CELSS and schematic diagrams of the BPS are included.

Using fuzzy rule-based knowledge model for optimum plating conditions search

NASA Astrophysics Data System (ADS)

Solovjev, D. S.; Solovjeva, I. A.; Litovka, Yu V.; Arzamastsev, A. A.; Glazkov, V. P.; L’vov, A. A.

2018-03-01

The paper discusses existing approaches to plating process modeling in order to decrease the distribution thickness of plating surface cover. However, these approaches do not take into account the experience, knowledge, and intuition of the decision-makers when searching the optimal conditions of electroplating technological process. The original approach to optimal conditions search for applying the electroplating coatings, which uses the rule-based model of knowledge and allows one to reduce the uneven product thickness distribution, is proposed. The block diagrams of a conventional control system of a galvanic process as well as the system based on the production model of knowledge are considered. It is shown that the fuzzy production model of knowledge in the control system makes it possible to obtain galvanic coatings of a given thickness unevenness with a high degree of adequacy to the experimental data. The described experimental results confirm the theoretical conclusions.

Pharmaceutical quality by design: product and process development, understanding, and control.

PubMed

Yu, Lawrence X

2008-04-01

The purpose of this paper is to discuss the pharmaceutical Quality by Design (QbD) and describe how it can be used to ensure pharmaceutical quality. The QbD was described and some of its elements identified. Process parameters and quality attributes were identified for each unit operation during manufacture of solid oral dosage forms. The use of QbD was contrasted with the evaluation of product quality by testing alone. The QbD is a systemic approach to pharmaceutical development. It means designing and developing formulations and manufacturing processes to ensure predefined product quality. Some of the QbD elements include: Defining target product quality profile; Designing product and manufacturing processes; Identifying critical quality attributes, process parameters, and sources of variability; Controlling manufacturing processes to produce consistent quality over time. Using QbD, pharmaceutical quality is assured by understanding and controlling formulation and manufacturing variables. Product testing confirms the product quality. Implementation of QbD will enable transformation of the chemistry, manufacturing, and controls (CMC) review of abbreviated new drug applications (ANDAs) into a science-based pharmaceutical quality assessment.

Spectral Dynamics Inc., ships hybrid, 316-channel data acquisition system to Sandia Labs.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schwartz, Douglas

2003-09-01

Spectral Dynamics announced the shipment of a 316-channel data acquisition system. The system was custom designed for the Light Initiated High Explosive (LIHE) facility at Sandia Labs in Albuquerque, New Mexico by Spectral Dynamics Advanced Research Products Group. This Spectral Dynamics data acquisition system was tailored to meet the unique LIHE environmental and testing requirements utilizing Spectral Dynamics commercial off the shelf (COTS) Jaguar and VIDAS products supplemented by SD Alliance partner's (COTS) products. 'This system is just the beginning of our cutting edge merged technology solutions,' stated Mark Remelman, Manager for the Spectral Dynamics Advanced Research Products Group. 'Thismore » Hybrid system has 316-channels of data acquisition capability, comprised of 102.4kHz direct to disk acquisition and 2.5MHz, 200Mhz & 500Mhz RAM based capabilities. In addition it incorporates the advanced bridge conditioning and dynamic configuration capabilities offered by Spectral Dynamics new Smart Interface Panel System (SIPS{trademark}).' After acceptance testing, Tony King, the Instrumentation Engineer facilitating the project for the Sandia LIHE group commented; 'The LIHE staff was very impressed with the design, construction, attention to detail and overall performance of the instrumentation system'. This system combines VIDAS, a leading edge fourth generation SD-VXI hardware and field-proven software system from SD's Advanced Research Products Group with SD's Jaguar, a multiple Acquisition Control Peripheral (ACP) system that allows expansion to hundreds of channels without sacrificing signal processing performance. Jaguar incorporates dedicated throughput disks for each ACP providing time streaming to disk at up to the maximum sample rate. Spectral Dynamics, Inc. is a leading worldwide supplier of systems and software for advanced computer-automated data acquisition, vibration testing, structural dynamics, explosive shock, high-speed transient capture, acoustic analysis, monitoring, measurement, control and backup. Spectral Dynamics products are used for research, design verification, product testing and process improvement by manufacturers of all types of electrical, electronic and mechanical products, as well as by universities and government-funded agencies. The Advanced Research Products Group is the newest addition to the Spectral Dynamics family. Their newest VXI data acquisition hardware pushes the envelope on capabilities and embodies the same rock solid design methodologies, which have always differentiated Spectral Dynamics from its competition.« less

Error-Free Software

NASA Technical Reports Server (NTRS)

1989-01-01

001 is an integrated tool suited for automatically developing ultra reliable models, simulations and software systems. Developed and marketed by Hamilton Technologies, Inc. (HTI), it has been applied in engineering, manufacturing, banking and software tools development. The software provides the ability to simplify the complex. A system developed with 001 can be a prototype or fully developed with production quality code. It is free of interface errors, consistent, logically complete and has no data or control flow errors. Systems can be designed, developed and maintained with maximum productivity. Margaret Hamilton, President of Hamilton Technologies, also directed the research and development of USE.IT, an earlier product which was the first computer aided software engineering product in the industry to concentrate on automatically supporting the development of an ultrareliable system throughout its life cycle. Both products originated in NASA technology developed under a Johnson Space Center contract.

[Prospects in getting accordance between chemical analytic control means and medical technical requirements to safety system concerning chemical weapons destruction].

PubMed

Rembovskiĭ, V R; Mogilenkova, L A; Savel'eva, E I

2005-01-01

The major unit monitoring chemical weapons destruction objects is a system of chemical analyticcontrol over the technologic process procedures and possibility of environment and workplace pollution withtoxicchemicals and their destruction products. At the same time, physical and chemical control means meet sanitary and hygienic requirements incompletely. To provide efficient control, internationally recognized approaches should be adapted to features of Russian system monitoring pollution of chemical weapons destruction objects with toxic chemicals.

Airline Operations Aid

NASA Technical Reports Server (NTRS)

1993-01-01

C Language Integrated Production System (CLIPS), a NASA-developed expert systems program, is used by American Airlines for three purposes: as a rapid prototyping tool; to develop production prototypes; and to develop production application. An example of the latter is CLIPS' use in "Hub S1AAshing," a knowledge based system that recommends contingency plans when severe schedule reductions must be made. Hub S1AAshing has replaced a manual, labor intensive process. It saves time and allows Operations Control Coordinators to handle more difficult situations. Because the system assimilates much of the information necessary to facilitate educated decision making, it minimizes negative impact in situations where it is impossible to operate all flights.

Optimization of controlled environments for hydroponic production of leaf lettuce for human life support in CELSS

NASA Technical Reports Server (NTRS)

Mitchell, C. A.; Knight, S. L.; Ford, T. L.

1986-01-01

A research project in the food production group of the Closed Ecological Life Support System (CELSS) program sought to define optimum conditions for photosynthetic productivity of a higher plant food crop. The effects of radiation and various atmospheric compositions were studied.

40 CFR 161.640 - Product performance data requirements table.

Code of Federal Regulations, 2013 CFR

2013-07-01

... pesticide product bears a claim to control pest microorganisms that pose a threat to human health and whose...) PESTICIDE PROGRAMS DATA REQUIREMENTS FOR REGISTRATION OF ANTIMICROBIAL PESTICIDES Data Requirement Tables... microbial pests associated with human and animal wastes (1) CR EP* 91-7 Products for treating water systems...

The effect of work system on the hand exposure of workers in 18F-FDG production centres.

PubMed

Wrzesień, Małgorzata

2018-05-07

The production of the 18 F isotope-the marker of deoxyglucose ( 18 F-FDG)-the radiopharmaceutical most commonly used in the oncological diagnostic technique of positron emission tomography, requires a cyclotron device. At present, there are nine facilities working in Poland that are equipped with cyclotrons used for producing the short-lived isotopes. The aim of the paper is to determine the hand exposure of workers employed in the two 18 F-FDG production centres taking in to account the production procedures and work system in those facilities. Measurements, which included all professional workers exposed to ionizing radiation that were employed in two facilities, were performed by using high-sensitivity thermoluminescent detectors during the routine activities of the personnel. The work system used at the production centre has an impact on the level of the recorded doses. Among the production procedures performed by the staff, the highest ionizing radiation doses have been received by the staff during the 18 F-FDG quality control. The maximum estimated annual Hp(0.07) for chemists from the quality control department can exceed the annual skin limit dose (500 mSv). The source of lowest doses on the hands are the cyclotron operating procedure and the 18 F-FDG production, provided that these procedures can't be combined with other production procedures.

Control of hot mix production by cold feed only : final report.

DOT National Transportation Integrated Search

1978-04-01

This report is concerned with an analysis of the gradation control possible with recently improved aggregate cold feed systems. The gradation control for three mix types produced in a screenless batch plant was monitored and statistically compared wi...

Modular radiochemistry synthesis system

DOEpatents

Satyamurthy, Nagichettiar; Barrio, Jorge R.; Amarasekera, Bernard; Van Dam, Michael R.; Olma, Sebastian; Williams, Dirk; Eddings, Mark; Shen, Clifton Kwang-Fu

2016-11-01

A modular chemical production system includes multiple modules for performing a chemical reaction, particularly of radiochemical compounds, from a remote location. One embodiment comprises a reaction vessel including a moveable heat source with the position thereof relative to the reaction vessel being controllable from a remote position. Alternatively the heat source may be fixed in location and the reaction vial is moveable into and out of the heat source. The reaction vessel has one or more sealing plugs, the positioning of which in relationship to the reaction vessel is controllable from a remote position. Also the one or more reaction vessel sealing plugs can include one or more conduits there through for delivery of reactants, gases at atmospheric or an elevated pressure, inert gases, drawing a vacuum and removal of reaction end products to and from the reaction vial, the reaction vial with sealing plug in position being operable at elevated pressures. The modular chemical production system is assembled from modules which can each include operating condition sensors and controllers configured for monitoring and controlling the individual modules and the assembled system from a remote position. Other modules include, but are not limited to a Reagent Storage and Delivery Module, a Cartridge Purification Module, a Microwave Reaction Module, an External QC/Analysis/Purification Interface Module, an Aliquotting Module, an F-18 Drying Module, a Concentration Module, a Radiation Counting Module, and a Capillary Reactor Module.

Modular radiochemistry synthesis system

DOEpatents

Satyamurthy, Nagichettiar; Barrio, Jorge R.; Amarasekera, Bernard; Van Dam, R. Michael; Olma, Sebastian; Williams, Dirk; Eddings, Mark; Shen, Clifton Kwang-Fu

2015-12-15

A modular chemical production system includes multiple modules for performing a chemical reaction, particularly of radiochemical compounds, from a remote location. One embodiment comprises a reaction vessel including a moveable heat source with the position thereof relative to the reaction vessel being controllable from a remote position. Alternatively the heat source may be fixed in location and the reaction vial is moveable into and out of the heat source. The reaction vessel has one or more sealing plugs, the positioning of which in relationship to the reaction vessel is controllable from a remote position. Also the one or more reaction vessel sealing plugs can include one or more conduits there through for delivery of reactants, gases at atmospheric or an elevated pressure, inert gases, drawing a vacuum and removal of reaction end products to and from the reaction vial, the reaction vial with sealing plug in position being operable at elevated pressures. The modular chemical production system is assembled from modules which can each include operating condition sensors and controllers configured for monitoring and controlling the individual modules and the assembled system from a remote position. Other modules include, but are not limited to a Reagent Storage and Delivery Module, a Cartridge Purification Module, a Microwave Reaction Module, an External QC/Analysis/Purification Interface Module, an Aliquotting Module, an F-18 Drying Module, a Concentration Module, a Radiation Counting Module, and a Capillary Reactor Module.

Modular radiochemistry synthesis system

DOEpatents

Satyamurthy, Nagichettiar; Barrio, Jorge R; Amarasekera, Bernard; Van Dam, R. Michael; Olma, Sebastian; Williams, Dirk; Eddings, Mark A; Shen, Clifton Kwang-Fu

2015-02-10

A modular chemical production system includes multiple modules for performing a chemical reaction, particularly of radiochemical compounds, from a remote location. One embodiment comprises a reaction vessel including a moveable heat source with the position thereof relative to the reaction vessel being controllable from a remote position. Alternatively the heat source may be fixed in location and the reaction vial is moveable into and out of the heat source. The reaction vessel has one or more sealing plugs, the positioning of which in relationship to the reaction vessel is controllable from a remote position. Also the one or more reaction vessel sealing plugs can include one or more conduits there through for delivery of reactants, gases at atmospheric or an elevated pressure, inert gases, drawing a vacuum and removal of reaction end products to and from the reaction vial, the reaction vial with sealing plug in position being operable at elevated pressures. The modular chemical production system is assembled from modules which can each include operating condition sensors and controllers configured for monitoring and controlling the individual modules and the assembled system from a remote position. Other modules include, but are not limited to a Reagent Storage and Delivery Module, a Cartridge Purification Module, a Microwave Reaction Module, an External QC/Analysis/Purification Interface Module, an Aliquotting Module, an F-18 Drying Module, a Concentration Module, a Radiation Counting Module, and a Capillary Reactor Module.

Controlling calcium precipitation in an integrated anaerobic-aerobic treatment system of a "zero-discharge" paper mill.

PubMed

van Lier, J B; Boncz, M A

2002-01-01

The pulp and paper industry uses significant amounts of water and energy for the paper production process. Closing the water cycles in this industry, therefore, promises large benefits for the environment and has the potential of huge cost savings for the industry. Closing the water cycle on the other hand also introduces problems with process water quality, quality of the end-product and scaling, owing to increased water contamination. An inline treatment system is discussed in which anaerobic-aerobic bioreactors perform a central role for removing both organic and inorganic pollutants from the process water cycle. In the proposed set-up, the organic compounds are converted to methane gas and reused for energy supply, while sulphur compounds are stripped from the process cycle and calcium carbonate is removed by precipitation. Improved control of the treatment system will direct the inorganic precipitates to a location where it does not adversely affect paper production and process water treatment. A simulation program for triggering and controlling CaCO3 precipitation was developed that takes both biological conversions and all relevant chemical equilibria in the system into account. Simulation results are in good agreement with data gathered in a full-scale "zero-emission" paper plant and indicate that control of CaCO3 precipitation can be improved, e.g. in the aerobic post-treatment. Alternatively, a separate precipitation unit could be considered.

[Effects of pesticides and plant bio-stimulants on the germination of chlamydospores and in vitro development of the nematophagous fungus Pochonia chlamydosporia].

PubMed

Ceiro, Wilson G; Arévalo, Jersys; Hidalgo-Díaz, Leopoldo

2015-01-01

The effects of pesticides and plant bio-stimulants used in protected vegetable production systems on the fungus Pochonia chlamydosporia are unknown. The effectiveness of P. chlamydosporia against Meloidogyne spp. could be affected by products used in protected vegetable production systems. Two in vitro assays were carried out to evaluate any potential effect that pesticides and bio-stimulants often used in these systems could have on the fungus. The effect on chlamydospore germination was evaluated in a first assay, and mycelia growth and sporulation in a second. With these results, the compatibility of each product with the fungus was determined. Chlamydospores germination was over 50% with the control, FitoMas E, Biobras-16 and Amidor. Lower results were observed with other products, with some of them even inhibiting germination completely. Fungal growth was potentiated by Biobras-16 to 106.23%, promoted up to 50-100% by the control, FitoMas E and Cuproflow, and was below 50% with the rest of the products.Cipermetrina, Benomilo, Zineb, Mitigan, Karate, FitoMas E and Amidor promoted fungal sporulation, which was below 50% with Cuproflow and completely inhibited by the other products. Fifty-four percent of the products evaluated were compatible with P. chlamydosporia, while 8% were toxic and 38%, very toxic. Cipermetrina, Karate, Amidor, Benomilo, Zineb, Mitigan and FitoMas E were compatible with P. chlamydosporia. If it is necessary to use any of the other products for integrated pest management in protected vegetable production systems, it is recommended to avoid direct contact with P. chlamydosporia. Copyright © 2013 Revista Iberoamericana de Micología. Published by Elsevier Espana. All rights reserved.

Enhanced Traceability for Bulk Processing of Sentinel-Derived Information Products

NASA Astrophysics Data System (ADS)

Lankester, Thomas; Hubbard, Steven; Knowelden, Richard

2016-08-01

The advent of widely available, systematically acquired and advanced Earth observations from the Sentinel platforms is spurring development of a wide range of derived information products. Whilst welcome, this rapid rate of development inevitably leads to some processing instability as algorithms and production steps are required to evolve accordingly. To mitigate this instability, the provenance of EO-derived information products needs to be traceable and transparent.Airbus Defence and Space (Airbus DS) has developed the Airbus Processing Cloud (APC) as a virtualised processing farm for bulk production of EO-derived data and information products. The production control system of the APC transforms internal configuration control information into an INSPIRE metadata file containing a stepwise set of processing steps and data source elements that provide the complete and transparent provenance of each product generated.

Airway and alveolar nitric oxide production, lung function, and pulmonary blood flow in sickle cell disease.

PubMed

Lunt, Alan; Ahmed, Na'eem; Rafferty, Gerrard F; Dick, Moira; Rees, David; Height, Sue; Thein, Swee Lay; Greenough, Anne

2016-02-01

Children with sickle cell disease (SCD) often have obstructive lung function abnormalities which could be due to asthma or increased pulmonary blood volume; it is important to determine the underlying mechanism to direct appropriate treatment. In asthmatics, exhaled nitric oxide (FeNO) is elevated. FeNO, however, can also be raised due to increased alveolar production. Our aim, therefore, was to determine if airway or alveolar NO production differed between SCD children and ethnic and age-matched controls. Lung function, airway NO flux and alveolar NO production, and effective pulmonary blood flow were assessed in 18 SCD children and 18 ethnic and age-matched controls. The SCD children compared to the controls had a higher respiratory system resistance (P = 0.0008), alveolar NO production (P = 0.0224), and pulmonary blood flow (P < 0.0001), but not airway NO flux. There was no significant correlation between FeNO and respiratory system resistance in either group, but in the SCD children, there were correlations between alveolar NO production (P = 0.0006) and concentration (P < 0.0001) and pulmonary blood flow. Airway NO flux was not elevated in the SCD children nor correlated with airways obstruction, suggesting that airways obstruction, at least in some SCD children, is not due to asthma.

Controlled Ecological Life Support System Breadboard Project - 1988

NASA Technical Reports Server (NTRS)

Knott, W. M.

1989-01-01

The Controlled Ecological Life Support System (CELSS) Breadboard Project, NASA's effort to develop the technology required to produce a functioning bioregenerative system, is discussed. The different phases of the project and its current status are described. The relationship between the project components are shown, and major project activities for fiscal years 1989-1993 are listed. The biomass production chamber to be used by the project is described.

Schools: Army Correspondence Course Program Catalog

DTIC Science & Technology

2001-10-26

Course Number: 061 M50) a. Objective. To provide an overview of targeting fundamentals to NCO with current or anticipated assignment to target production...D15) a. Objective/Scope. To provide students an overview of the DOD Reutilization and Marketing System. Emphasis is placed upon the organization and...providing an overview of financial systems, statutory controls, and programs. This course encompasses defense financial systems and controls to include

A mineral seed coating for control of seedling diseases of alfalfa suitable for organic production systems

USDA-ARS?s Scientific Manuscript database

Most alfalfa seed is treated with the systemic fungicide mefenoxam (Apron XL) for control of soilborne seedling diseases. However, Apron XL does not have activity against Aphanomyces euteiches, the causal agent of Aphanomyces root rot (ARR), which is an important component of the alfalfa root rot co...

Dehydration of Traditional Dried Instant Noodle (Mee Siput) Using Controlled Temperature & Humidity Dryer

NASA Astrophysics Data System (ADS)

Mamat, K. A.; Yusof, M. S.; Yusoff, Wan Fauziah Wan; Zulafif Rahim, M.; Hassan, S.; Rahman, M. Qusyairi. A.; Karim, M. A. Abd

2017-05-01

Drying process is an essential step to produce instant noodles. Yet, the industries especially Small and Medium Enterprises (SMEs), is seeking for an efficient method to dry the noodles. This paper discusses the performance of an invented drying system which employed heating and humidifying process. The drying system was tested using 30 kilogram of the raw noodle known as “Mee Siput”. Temperature controlled system were used in the study to control the temperature of the drying process and prevent the dried noodles from damage by maintaining the temperature of lower than 80°C. The analysis shows that the system was drastically decreased the humidity from 80% to 40% just after 200 minutes of the drying process. The complete dehydration time of noodle has also decreased to only 4 hours from 16 hours when using traditional drying system without sacrificed the good quality of the dried noodle. In overall, the invented system believed to increase the production capacity of the noodle, reduce cost of production which would highly beneficial for Small Medium Industries (SMEs) in Malaysia.

Real-time quality assurance testing using photonic techniques: Application to iodine water system

NASA Technical Reports Server (NTRS)

Arendale, W. F.; Hatcher, Richard; Garlington, Yadilett; Harwell, Jack; Everett, Tracey

1990-01-01

A feasibility study of the use of inspection systems incorporating photonic sensors and multivariate analyses to provide an instrumentation system that in real-time assures quality and that the system in control has been conducted. A system is in control when the near future of the product quality is predictable. Off-line chemical analyses can be used for a chemical process when slow kinetics allows time to take a sample to the laboratory and the system provides a recovery mechanism that returns the system to statistical control without intervention of the operator. The objective for this study has been the implementation of do-it-right-the-first-time and just-in-time philosophies. The Environment Control and Life Support Systems (ECLSS) water reclamation system that adds iodine for biocidal control is an ideal candidate for the study and implementation of do-it-right-the-first-time technologies.

Project W-211, initial tank retrieval systems, retrieval control system software configuration management plan

DOE Office of Scientific and Technical Information (OSTI.GOV)

RIECK, C.A.

1999-02-23

This Software Configuration Management Plan (SCMP) provides the instructions for change control of the W-211 Project, Retrieval Control System (RCS) software after initial approval/release but prior to the transfer of custody to the waste tank operations contractor. This plan applies to the W-211 system software developed by the project, consisting of the computer human-machine interface (HMI) and programmable logic controller (PLC) software source and executable code, for production use by the waste tank operations contractor. The plan encompasses that portion of the W-211 RCS software represented on project-specific AUTOCAD drawings that are released as part of the C1 definitive designmore » package (these drawings are identified on the drawing list associated with each C-1 package), and the associated software code. Implementation of the plan is required for formal acceptance testing and production release. The software configuration management plan does not apply to reports and data generated by the software except where specifically identified. Control of information produced by the software once it has been transferred for operation is the responsibility of the receiving organization.« less

A circular model for song motor control in Serinus canaria

PubMed Central

Alonso, Rodrigo G.; Trevisan, Marcos A.; Amador, Ana; Goller, Franz; Mindlin, Gabriel B.

2015-01-01

Song production in songbirds is controlled by a network of nuclei distributed across several brain regions, which drives respiratory and vocal motor systems to generate sound. We built a model for birdsong production, whose variables are the average activities of different neural populations within these nuclei of the song system. We focus on the predictions of respiratory patterns of song, because these can be easily measured and therefore provide a validation for the model. We test the hypothesis that it is possible to construct a model in which (1) the activity of an expiratory related (ER) neural population fits the observed pressure patterns used by canaries during singing, and (2) a higher forebrain neural population, HVC, is sparsely active, simultaneously with significant motor instances of the pressure patterns. We show that in order to achieve these two requirements, the ER neural population needs to receive two inputs: a direct one, and its copy after being processed by other areas of the song system. The model is capable of reproducing the measured respiratory patterns and makes specific predictions on the timing of HVC activity during their production. These results suggest that vocal production is controlled by a circular network rather than by a simple top-down architecture. PMID:25904860

Fault-tolerant Control of a Cyber-physical System

NASA Astrophysics Data System (ADS)

Roxana, Rusu-Both; Eva-Henrietta, Dulf

2017-10-01

Cyber-physical systems represent a new emerging field in automatic control. The fault system is a key component, because modern, large scale processes must meet high standards of performance, reliability and safety. Fault propagation in large scale chemical processes can lead to loss of production, energy, raw materials and even environmental hazard. The present paper develops a multi-agent fault-tolerant control architecture using robust fractional order controllers for a (13C) cryogenic separation column cascade. The JADE (Java Agent DEvelopment Framework) platform was used to implement the multi-agent fault tolerant control system while the operational model of the process was implemented in Matlab/SIMULINK environment. MACSimJX (Multiagent Control Using Simulink with Jade Extension) toolbox was used to link the control system and the process model. In order to verify the performance and to prove the feasibility of the proposed control architecture several fault simulation scenarios were performed.

Systems, methods, and products for graphically illustrating and controlling a droplet actuator

NASA Technical Reports Server (NTRS)

Brafford, Keith R. (Inventor); Pamula, Vamsee K. (Inventor); Paik, Philip Y. (Inventor); Pollack, Michael G. (Inventor); Sturmer, Ryan A. (Inventor); Smith, Gregory F. (Inventor)

2010-01-01

Systems for controlling a droplet microactuator are provided. According to one embodiment, a system is provided and includes a controller, a droplet microactuator electronically coupled to the controller, and a display device displaying a user interface electronically coupled to the controller, wherein the system is programmed and configured to permit a user to effect a droplet manipulation by interacting with the user interface. According to another embodiment, a system is provided and includes a processor, a display device electronically coupled to the processor, and software loaded and/or stored in a storage device electronically coupled to the controller, a memory device electronically coupled to the controller, and/or the controller and programmed to display an interactive map of a droplet microactuator. According to yet another embodiment, a system is provided and includes a controller, a droplet microactuator electronically coupled to the controller, a display device displaying a user interface electronically coupled to the controller, and software for executing a protocol loaded and/or stored in a storage device electronically coupled to the controller, a memory device electronically coupled to the controller, and/or the controller.

An Analysis of the Future Combat Systems (FCS) Spin Out 1 Low-Rate of Initial Production (LRIP) Contract

DTIC Science & Technology

2009-08-24

interests are strategic resource management, strategic control, and corporate financial reporting. Joseph G. San Miguel Professor Graduate School of...Officer PM – Program Manager SAIC – Science Applications International Corporation SAP – Systems Applications and Products SDD – System Development and...the award of the multi-billion dollar FCS program management contract to the Boeing Company and Science Applications International Corporation (SAIC

Pitch perception and production in congenital amusia: Evidence from Cantonese speakers.

PubMed

Liu, Fang; Chan, Alice H D; Ciocca, Valter; Roquet, Catherine; Peretz, Isabelle; Wong, Patrick C M

2016-07-01

This study investigated pitch perception and production in speech and music in individuals with congenital amusia (a disorder of musical pitch processing) who are native speakers of Cantonese, a tone language with a highly complex tonal system. Sixteen Cantonese-speaking congenital amusics and 16 controls performed a set of lexical tone perception, production, singing, and psychophysical pitch threshold tasks. Their tone production accuracy and singing proficiency were subsequently judged by independent listeners, and subjected to acoustic analyses. Relative to controls, amusics showed impaired discrimination of lexical tones in both speech and non-speech conditions. They also received lower ratings for singing proficiency, producing larger pitch interval deviations and making more pitch interval errors compared to controls. Demonstrating higher pitch direction identification thresholds than controls for both speech syllables and piano tones, amusics nevertheless produced native lexical tones with comparable pitch trajectories and intelligibility as controls. Significant correlations were found between pitch threshold and lexical tone perception, music perception and production, but not between lexical tone perception and production for amusics. These findings provide further evidence that congenital amusia is a domain-general language-independent pitch-processing deficit that is associated with severely impaired music perception and production, mildly impaired speech perception, and largely intact speech production.

Pitch perception and production in congenital amusia: Evidence from Cantonese speakers

PubMed Central

Liu, Fang; Chan, Alice H. D.; Ciocca, Valter; Roquet, Catherine; Peretz, Isabelle; Wong, Patrick C. M.

2016-01-01

This study investigated pitch perception and production in speech and music in individuals with congenital amusia (a disorder of musical pitch processing) who are native speakers of Cantonese, a tone language with a highly complex tonal system. Sixteen Cantonese-speaking congenital amusics and 16 controls performed a set of lexical tone perception, production, singing, and psychophysical pitch threshold tasks. Their tone production accuracy and singing proficiency were subsequently judged by independent listeners, and subjected to acoustic analyses. Relative to controls, amusics showed impaired discrimination of lexical tones in both speech and non-speech conditions. They also received lower ratings for singing proficiency, producing larger pitch interval deviations and making more pitch interval errors compared to controls. Demonstrating higher pitch direction identification thresholds than controls for both speech syllables and piano tones, amusics nevertheless produced native lexical tones with comparable pitch trajectories and intelligibility as controls. Significant correlations were found between pitch threshold and lexical tone perception, music perception and production, but not between lexical tone perception and production for amusics. These findings provide further evidence that congenital amusia is a domain-general language-independent pitch-processing deficit that is associated with severely impaired music perception and production, mildly impaired speech perception, and largely intact speech production. PMID:27475178

Spatial and Functional Organization of Pig Trade in Different European Production Systems: Implications for Disease Prevention and Control.

PubMed

Relun, Anne; Grosbois, Vladimir; Sánchez-Vizcaíno, José Manuel; Alexandrov, Tsviatko; Feliziani, Francesco; Waret-Szkuta, Agnès; Molia, Sophie; Etter, Eric Marcel Charles; Martínez-López, Beatriz

2016-01-01

Understanding the complexity of live pig trade organization is a key factor to predict and control major infectious diseases, such as classical swine fever (CSF) or African swine fever (ASF). Whereas the organization of pig trade has been described in several European countries with indoor commercial production systems, little information is available on this organization in other systems, such as outdoor or small-scale systems. The objective of this study was to describe and compare the spatial and functional organization of live pig trade in different European countries and different production systems. Data on premise characteristics and pig movements between premises were collected during 2011 from Bulgaria, France, Italy, and Spain, which swine industry is representative of most of the production systems in Europe (i.e., commercial vs. small-scale and outdoor vs. indoor). Trade communities were identified in each country using the Walktrap algorithm. Several descriptive and network metrics were generated at country and community levels. Pig trade organization showed heterogeneous spatial and functional organization. Trade communities mostly composed of indoor commercial premises were identified in western France, northern Italy, northern Spain, and north-western Bulgaria. They covered large distances, overlapped in space, demonstrated both scale-free and small-world properties, with a role of trade operators and multipliers as key premises. Trade communities involving outdoor commercial premises were identified in western Spain, south-western and central France. They were more spatially clustered, demonstrated scale-free properties, with multipliers as key premises. Small-scale communities involved the majority of premises in Bulgaria and in central and Southern Italy. They were spatially clustered and had scale-free properties, with key premises usually being commercial production premises. These results indicate that a disease might spread very differently according to the production system and that key premises could be targeted to more cost-effectively control diseases. This study provides useful epidemiological information and parameters that could be used to design risk-based surveillance strategies or to more accurately model the risk of introduction or spread of devastating swine diseases, such as ASF, CSF, or foot-and-mouth disease.

Spatial and Functional Organization of Pig Trade in Different European Production Systems: Implications for Disease Prevention and Control

PubMed Central

Relun, Anne; Grosbois, Vladimir; Sánchez-Vizcaíno, José Manuel; Alexandrov, Tsviatko; Feliziani, Francesco; Waret-Szkuta, Agnès; Molia, Sophie; Etter, Eric Marcel Charles; Martínez-López, Beatriz

2016-01-01

Understanding the complexity of live pig trade organization is a key factor to predict and control major infectious diseases, such as classical swine fever (CSF) or African swine fever (ASF). Whereas the organization of pig trade has been described in several European countries with indoor commercial production systems, little information is available on this organization in other systems, such as outdoor or small-scale systems. The objective of this study was to describe and compare the spatial and functional organization of live pig trade in different European countries and different production systems. Data on premise characteristics and pig movements between premises were collected during 2011 from Bulgaria, France, Italy, and Spain, which swine industry is representative of most of the production systems in Europe (i.e., commercial vs. small-scale and outdoor vs. indoor). Trade communities were identified in each country using the Walktrap algorithm. Several descriptive and network metrics were generated at country and community levels. Pig trade organization showed heterogeneous spatial and functional organization. Trade communities mostly composed of indoor commercial premises were identified in western France, northern Italy, northern Spain, and north-western Bulgaria. They covered large distances, overlapped in space, demonstrated both scale-free and small-world properties, with a role of trade operators and multipliers as key premises. Trade communities involving outdoor commercial premises were identified in western Spain, south-western and central France. They were more spatially clustered, demonstrated scale-free properties, with multipliers as key premises. Small-scale communities involved the majority of premises in Bulgaria and in central and Southern Italy. They were spatially clustered and had scale-free properties, with key premises usually being commercial production premises. These results indicate that a disease might spread very differently according to the production system and that key premises could be targeted to more cost-effectively control diseases. This study provides useful epidemiological information and parameters that could be used to design risk-based surveillance strategies or to more accurately model the risk of introduction or spread of devastating swine diseases, such as ASF, CSF, or foot-and-mouth disease. PMID:26870738

High cell density cultivation and recombinant protein production with Escherichia coli in a rocking-motion-type bioreactor

PubMed Central

2010-01-01

Background Single-use rocking-motion-type bag bioreactors provide advantages compared to standard stirred tank bioreactors by decreased contamination risks, reduction of cleaning and sterilization time, lower investment costs, and simple and cheaper validation. Currently, they are widely used for cell cultures although their use for small and medium scale production of recombinant proteins with microbial hosts might be very attractive. However, the utilization of rocking- or wave-induced motion-type bioreactors for fast growing aerobic microbes is limited because of their lower oxygen mass transfer rate. A conventional approach to reduce the oxygen demand of a culture is the fed-batch technology. New developments, such as the BIOSTAT® CultiBag RM system pave the way for applying advanced fed-batch control strategies also in rocking-motion-type bioreactors. Alternatively, internal substrate delivery systems such as EnBase® Flo provide an opportunity for adopting simple to use fed-batch-type strategies to shaken cultures. Here, we investigate the possibilities which both strategies offer in view of high cell density cultivation of E. coli and recombinant protein production. Results Cultivation of E. coli in the BIOSTAT® CultiBag RM system in a conventional batch mode without control yielded an optical density (OD600) of 3 to 4 which is comparable to shake flasks. The culture runs into oxygen limitation. In a glucose limited fed-batch culture with an exponential feed and oxygen pulsing, the culture grew fully aerobically to an OD600 of 60 (20 g L-1 cell dry weight). By the use of an internal controlled glucose delivery system, EnBase® Flo, OD600 of 30 (10 g L-1 cell dry weight) is obtained without the demand of computer controlled external nutrient supply. EnBase® Flo also worked well in the CultiBag RM system with a recombinant E. coli RB791 strain expressing a heterologous alcohol dehydrogenase (ADH) to very high levels, indicating that the enzyme based feed supply strategy functions well for recombinant protein production also in a rocking-motion-type bioreactor. Conclusions Rocking-motion-type bioreactors may provide an interesting alternative to standard cultivation in bioreactors for cultivation of bacteria and recombinant protein production. The BIOSTAT® Cultibag RM system with the single-use sensors and advanced control system paves the way for the fed-batch technology also to rocking-motion-type bioreactors. It is possible to reach cell densities which are far above shake flasks and typical for stirred tank reactors with the improved oxygen transfer rate. For more simple applications the EnBase® Flo method offers an easy and robust solution for rocking-motion-systems which do not have such advanced control possibilities. PMID:20509968

On optimal control problem for conservation law modelling one class of highly re-entrant production systems

NASA Astrophysics Data System (ADS)

D'Apice, Ciro; Kogut, Peter I.

2017-07-01

We discuss the optimal control problem stated as the minimization in the L2-sense of the mismatch between the actual out-flux and a demand forecast for a hyperbolic conservation law that models a highly re-entrant production system. The output of the factory is described as a function of the work in progress and the position of the so-called push-pull point (PPP) where we separate the beginning of the factory employing a push policy from the end of the factory, which uses a pull policy.

Effective organizational solutions for implementation of DBMS software packages

NASA Technical Reports Server (NTRS)

Jones, D.

1984-01-01

The space telescope management information system development effort is a guideline for discussing effective organizational solutions used in implementing DBMS software. Focus is on the importance of strategic planning. The value of constructing an information system architecture to conform to the organization's managerial needs, the need for a senior decision maker, dealing with shifting user requirements, and the establishment of a reliable working relationship with the DBMS vendor are examined. Requirements for a schedule to demonstrate progress against a defined timeline and the importance of continued monitoring for production software control, production data control, and software enhancements are also discussed.

Applications in Robotics and Controls

NASA Astrophysics Data System (ADS)

Youcef-Toumi, Kamal

2008-06-01

Recent industry trends have set new standards in business dealings and trades. Issues such as time to market, shoter market wondows, product performance, rapid increase of product complexity, costly mistakes, costly late introductions, and customer expectations have changed significantly. These trends have also influenced to a great extend the academic world. Some of these trends will be illustrated through examples which include automated systems, robotics, biotechnollogy, and nanotechnology. The examples will include concepts and prototypes of engineering systems in the macro, micro and nanodomains. The presentation also amphasizes the merging of the traditionally segregated disciplines into one multidisciplinary modeling, design, optimization and control approach.

Development of a sensitivity analysis technique for multiloop flight control systems

NASA Technical Reports Server (NTRS)

Vaillard, A. H.; Paduano, J.; Downing, D. R.

1985-01-01

This report presents the development and application of a sensitivity analysis technique for multiloop flight control systems. This analysis yields very useful information on the sensitivity of the relative-stability criteria of the control system, with variations or uncertainties in the system and controller elements. The sensitivity analysis technique developed is based on the computation of the singular values and singular-value gradients of a feedback-control system. The method is applicable to single-input/single-output as well as multiloop continuous-control systems. Application to sampled-data systems is also explored. The sensitivity analysis technique was applied to a continuous yaw/roll damper stability augmentation system of a typical business jet, and the results show that the analysis is very useful in determining the system elements which have the largest effect on the relative stability of the closed-loop system. As a secondary product of the research reported here, the relative stability criteria based on the concept of singular values were explored.

Biomass production and nitrogen dynamics in an integrated aquaculture/agriculture system

NASA Technical Reports Server (NTRS)

Owens, L. P.; Hall, C. R.

1990-01-01

A combined aquaculture/agriculture system that brings together the three major components of a Controlled Ecological Life Support System (CELSS) - biomass production, biomass processing, and waste recycling - was developed to evaluate ecological processes and hardware requirements necessary to assess the feasibility of and define design criteria for integration into the Kennedy Space Center (KSC) Breadboard Project. The system consists of a 1 square meter plant growth area, a 500 liter fish culture tank, and computerized monitoring and control hardware. Nutrients in the hydrophonic solution were derived from fish metabolites and fish food leachate. In five months of continuous operation, 27.0 kg of lettuce tops, 39.9 kg of roots and biofilm, and 6.6 kg of fish (wet weights) were produced with 12.7 kg of fish food input. Based on dry weights, a biomass conversion index of 0.52 was achieved. A nitrogen budget was derived to determine partitioning of nitrogen within various compartments of the system. Accumulating nitrogen in the hypoponic solution indicated a need to enlarge the plant growth area, potentially increasing the biomass production and improving the biomass conversion index.

An expert system for benzole recovery plant

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ishiguro, H.; Matsumura, S.; Kawashima, A.

1993-01-01

In the By-Product Plant of NKK's Keihin Works, systematization efforts were made in 1988, including integration of the control rooms, introduction of computers and installation of automatic analyzers. This has however increased the burden on operators with a huge volume of data, and a delay in coping with an operational abnormality might expand risk and extent of damages. There is, on the other hand, a pressing need to take measures to accommodate sophisticated operations resulting from the pursuit of high productivity operation. For the purpose of avoiding these possible inconveniences, development of a real-time operation system has been tried inmore » an attempt to improve safety and operating techniques and productivity in the benzole recovery plant. An offline system based on manual entry of operating data for diagnosis of operation and abnormality was developed in 1990, and an online real-time system operating by incorporating real-time operating data was developed in 1991, which is now smoothly operating in commercial operations. This report presents an outline of the benzole recovery operation diagnosis control expert system.« less

Guidance, steering, load relief and control of an asymmetric launch vehicle. M.S. Thesis - MIT

NASA Technical Reports Server (NTRS)

Boelitz, Frederick W.

1989-01-01

A new guidance, steering, and control concept is described and evaluated for the Third Phase of an asymmetrical configuration of the Advanced Launch System (ALS). The study also includes the consideration of trajectory shaping issues and trajectory design as well as the development of angular rate, angular acceleration, angle of attack, and dynamic pressure estimators. The Third Phase guidance, steering and control system is based on controlling the acceleration-direction of the vehicle after an initial launch maneuver. Unlike traditional concepts, the alignment of the estimated and commanded acceleration-directions is unimpaired by an add-on load relief. Instead, the acceleration-direction steering-control system features a control override that limits the product of estimated dynamic pressure and estimated angle of attack. When this product is not being limited, control is based exclusively on the commanded acceleration-direction without load relief. During limiting, control is based on nulling the error between the limited angle of attack and the estimated angle of attack. This limiting feature provides full freedom to the acceleration-direction steering and control to shape the trajectory within the limit, and also gives full priority to the limiting of angle of attack when necessary. The flight software concepts were analyzed on the basis of their effects on pitch plane motion.

Increasing Competition for Spares within AFLC (Air Force Logistics Center). Revision.

DTIC Science & Technology

1982-11-30

Managers 45 On Competing the Production of Weapon Systems 46 Sole Source and Competitive Price Trends in Spare Parts Acquisition 47 Controlled...future directions in research and policy . 3- TOPIC: Acquisition TYPE: AFIT Thesis TITLE: Spares Acquisition Integrated with Production and Its...evaluate Air Force management policies , procedures, practices, and controls over the acquisition and pricing of spare parts. Specific objectives

PCMO L01-Setting Specifications for Biological Investigational Medicinal Products.

PubMed

Krause, Stephan O

2015-01-01

This paper provides overall guidance and best practices for the setting of specifications for clinical biological drug substances and drug products within the framework of ICH guidelines on pharmaceutical development [Q8(R2) and Q11], quality risk management (Q9), and quality systems (Q10). A review is provided of the current regulatory expectations for the specification setting process as part of a control strategy during product development, pointing to existing challenges for the investigational new drug/investigational medicinal product dossier (IND/IMPD) sponsor. A case study illustrates how the investigational medicinal product specification revision process can be managed within a flexible quality system, and how specifications can be set and justified for early and late development stages. This paper provides an overview for the setting of product specifications for investigational medicinal products used in clinical trials. A case study illustrates how product specifications of investigational medicinal products can be justified and managed within a modern product quality system. © PDA, Inc. 2015.

Mapping of beef, sheep and goat food systems in Nairobi - A framework for policy making and the identification of structural vulnerabilities and deficiencies.

PubMed

Alarcon, Pablo; Fèvre, Eric M; Murungi, Maurice K; Muinde, Patrick; Akoko, James; Dominguez-Salas, Paula; Kiambi, Stella; Ahmed, Sohel; Häsler, Barbara; Rushton, Jonathan

2017-03-01

Nairobi is a large rapidly-growing city whose demand for beef, mutton and goat products is expected to double by 2030. The study aimed to map the Nairobi beef, sheep and goat systems structure and flows to identify deficiencies and vulnerabilities to shocks. Cross-sectional data were collected through focus group discussions and interviews with people operating in Nairobi ruminant livestock and meat markets and in the large processing companies. Qualitative and quantitative data were obtained about the type of people, animals, products and value adding activities in the chains, and their structural, spatial and temporal interactions. Mapping analysis was done in three different dimensions: people and product profiling (interactions of people and products), geographical (routes of animals and products) and temporal mapping (seasonal fluctuations). The results obtained were used to identify structural deficiencies and vulnerability factors in the system. Results for the beef food system showed that 44-55% of the city's beef supply flows through the 'local terminal markets', but that 54-64% of total supply is controlled by one 'meat market'. Numerous informal chains were identified, with independent livestock and meat traders playing a pivotal role in the functionality of these systems, and where most activities are conducted with inefficient quality control and under scarce and inadequate infrastructure and organisation, generating wastage and potential food safety risks in low quality meat products. Geographical and temporal analysis showed the critical areas influencing the different markets, with larger markets increasing their market share in the low season. Large processing companies, partly integrated, operate with high quality infrastructures, but with up to 60% of their beef supply depending on similar routes as the informal markets. Only these companies were involved in value addition activities, reaching high-end markets, but also dominating the distribution of popular products, such as beef sausages, to middle and low-end market. For the small ruminant food system, 73% of the low season supply flows through a single large informal market, Kiamaiko, located in an urban informal settlement. No grading is done for these animals or the meat produced. Large companies were reported to export up to 90% of their products. Lack of traceability and control of animal production was a common feature in all chains. The mapping presented provides a framework for policy makers and institutions to understand and design improvement plans for the Nairobi ruminant food system. The structural deficiencies and vulnerabilities identified here indicate the areas of intervention needed.

Recirculating Aquaculture (4th edition)

USDA-ARS?s Scientific Manuscript database

Typically recirculating (closed) aquatic production systems have higher capital and operating costs than many of the extensive systems such as cage culture in natural waters and raceway and/or pond culture systems. However, when the control provided by recirculating systems and the benefits this env...

Total Quality Management Guide. Volume 2. A Guide to Implementation

DTIC Science & Technology

1990-02-15

Kaoru . Guide to Quality Control. Asian Productivity Organization. 1984. Ishikawa , Kaoru . What is Total Quality Control? The Japanese Way. Englewood...of the new Systems Age. The theories of Deming, Juran, Ishikawa , and other management methods that still predominate are pioneers of Systems Age...Feigenbaum, Armand V. Total Quality Control. New York: McGraw-Hill Book Company. 1983. bnai, Masaaki. Kaizen. New York: Random House. 1986. Ishikawa

A Comparison of Photocatalytic Oxidation Reactor Performance for Spacecraft Cabin Trace Contaminant Control Applications

NASA Technical Reports Server (NTRS)

Perry, Jay L.; Frederick, Kenneth R.; Scott, Joseph P.; Reinermann, Dana N.

2011-01-01

Photocatalytic oxidation (PCO) is a maturing process technology that shows potential for spacecraft life support system application. Incorporating PCO into a spacecraft cabin atmosphere revitalization system requires an understanding of basic performance, particularly with regard to partial oxidation product production. Four PCO reactor design concepts have been evaluated for their effectiveness for mineralizing key trace volatile organic com-pounds (VOC) typically observed in crewed spacecraft cabin atmospheres. Mineralization efficiency and selectivity for partial oxidation products are compared for the reactor design concepts. The role of PCO in a spacecraft s life support system architecture is discussed.

A 'breadboard' biomass production chamber for CELSS

NASA Technical Reports Server (NTRS)

Prince, Ralph P.; Knott, William M., III; Hilding, Suzanne E.; Mack, Tommy L.

1987-01-01

The Breadboard Project of the Controlled Ecological Life Support System (CELSS) Program is the first attempt by NASA to integrate the primary components of a bioregenerative life support system into a functioning system. The central component of this project is a Biomass Production Chamber (BPC). The BPC is under construction, and when finished will be sealed for the study of the flux of gases, liquids, and solids through the production module of a CELSS. Features of the CELSS breadboard facility will be covered as will design requirements for the BPC. Cultural practices developed for wheat for the BPC wil be discussed.

Using the pallet costing system to determine costs and stay competitive in the pallet industry

Treesearch

A. Jefferson Jr. Palmer; Bruce G. Hansen; Bruce G. Hansen

2002-01-01

In order to stay competitive and keep production costs at a minimum, wood pallet manufacturers must plan, monitor, and control their various production activities. Cost information on pallet manufacturing operations, must be gathered and analyzed so that the plant manager can determine whether certain activities are efficient and profitable. The Pallet Costing System (...

System 6: A pricing strategy for long blanks

Treesearch

Hugh W. Reynolds; Bruce G. Hansen; Bruce G. Hansen

1986-01-01

In System 6, small-diameter, low-grade hardwood timber is used to make blanks in standard sizes. Blanks are made in one thickness and one quality class but in all the standard lengths during each production run. The quantity of blanks per length can be varied, while keeping total yield high, by using proper production control techniques. However, when the percentage of...

Interference evaluation between manifold and wet Christmas tree CP systems

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brasil, S.L.D.C.; Baptista, W.

2000-05-01

Offshore production wells are controlled by valves installed in the marine soil, called wet Christmas trees (WCTs). A manifold receives the production of several wells and transports it to the platform. The manifold is cathodically protected by Al anodes and the WCT by Zn anodes. A computer simulation was carried out to evaluate the interference between the equipment cathodic protection systems.

Environmental Impacts of Arthropod Biological Control: An Ecological Perspective

USDA-ARS?s Scientific Manuscript database

Arthropod biological control has long been used against insect and mite pests in agriculture production systems, forests, and other natural ecosystems. Depending on the methods of deploying natural enemies and the type of control agents (herbivores, parasitoids, and/or predators), potential environ...

Numerical research of the optimal control problem in the semi-Markov inventory model

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gorshenin, Andrey K.; Belousov, Vasily V.; Shnourkoff, Peter V.

2015-03-10

This paper is devoted to the numerical simulation of stochastic system for inventory management products using controlled semi-Markov process. The results of a special software for the system’s research and finding the optimal control are presented.

A new approach for strawberry disease control

USDA-ARS?s Scientific Manuscript database

Strawberry is grown around the world in different production systems and diverse environmental conditions, which creates challenges in controlling fruit-rot causing pathogens before and after harvest. Fungicides have been traditionally used to control these diseases, and in some areas, as many as 2...

Adaptive management for ecosystem services (j/a) | Science ...

EPA Pesticide Factsheets

Management of natural resources for the production of ecosystem services, which are vital for human well-being, is necessary even when there is uncertainty regarding system response to management action. This uncertainty is the result of incomplete controllability, complex internal feedbacks, and non-linearity that often interferes with desired management outcomes, and insufficient understanding of nature and people. Adaptive management was developed to reduce such uncertainty. We present a framework for the application of adaptive management for ecosystem services that explicitly accounts for cross-scale tradeoffs in the production of ecosystem services. Our framework focuses on identifying key spatiotemporal scales (plot, patch, ecosystem, landscape, and region) that encompass dominant structures and processes in the system, and includes within- and cross-scale dynamics, ecosystem service tradeoffs, and management controllability within and across scales. Resilience theory recognizes that a limited set of ecological processes in a given system regulate ecosystem services, yet our understanding of these processes is poorly understood. If management actions erode or remove these processes, the system may shift into an alternative state unlikely to support the production of desired services. Adaptive management provides a process to assess the underlying within and cross-scale tradeoffs associated with production of ecosystem services while proceeding with manage

Automated information system for analysis and prediction of production situations in blast furnace plant

NASA Astrophysics Data System (ADS)

Lavrov, V. V.; Spirin, N. A.

2016-09-01

Advances in modern science and technology are inherently connected with the development, implementation, and widespread use of computer systems based on mathematical modeling. Algorithms and computer systems are gaining practical significance solving a range of process tasks in metallurgy of MES-level (Manufacturing Execution Systems - systems controlling industrial process) of modern automated information systems at the largest iron and steel enterprises in Russia. This fact determines the necessity to develop information-modeling systems based on mathematical models that will take into account the physics of the process, the basics of heat and mass exchange, the laws of energy conservation, and also the peculiarities of the impact of technological and standard characteristics of raw materials on the manufacturing process data. Special attention in this set of operations for metallurgic production is devoted to blast-furnace production, as it consumes the greatest amount of energy, up to 50% of the fuel used in ferrous metallurgy. The paper deals with the requirements, structure and architecture of BF Process Engineer's Automated Workstation (AWS), a computer decision support system of MES Level implemented in the ICS of the Blast Furnace Plant at Magnitogorsk Iron and Steel Works. It presents a brief description of main model subsystems as well as assumptions made in the process of mathematical modelling. Application of the developed system allows the engineering and process staff to analyze online production situations in the blast furnace plant, to solve a number of process tasks related to control of heat, gas dynamics and slag conditions of blast-furnace smelting as well as to calculate the optimal composition of blast-furnace slag, which eventually results in increasing technical and economic performance of blast-furnace production.

Progress in understanding the molecular oxygen paradox - function of mitochondrial reactive oxygen species in cell signaling.

PubMed

Kuksal, Nidhi; Chalker, Julia; Mailloux, Ryan J

2017-10-26

The molecular oxygen (O2) paradox was coined to describe its essential nature and toxicity. The latter characteristic of O2 is associated with the formation of reactive oxygen species (ROS), which can damage structures vital for cellular function. Mammals are equipped with antioxidant systems to fend off the potentially damaging effects of ROS. However, under certain circumstances antioxidant systems can become overwhelmed leading to oxidative stress and damage. Over the past few decades, it has become evident that ROS, specifically H2O2, are integral signaling molecules complicating the previous logos that oxyradicals were unfortunate by-products of oxygen metabolism that indiscriminately damage cell structures. To avoid its potential toxicity whilst taking advantage of its signaling properties, it is vital for mitochondria to control ROS production and degradation. H2O2 elimination pathways are well characterized in mitochondria. However, less is known about how H2O2 production is controlled. The present review examines the importance of mitochondrial H2O2 in controlling various cellular programs and emerging evidence for how production is regulated. Recently published studies showing how mitochondrial H2O2 can be used as a secondary messenger will be discussed in detail. This will be followed with a description of how mitochondria use S-glutathionylation to control H2O2 production.

Stability studies needed to define the handling and transport conditions of sensitive pharmaceutical or biotechnological products.

PubMed

Ammann, Claude

2011-12-01

Many pharmaceutical or biotechnological products require transport using temperature-controlled systems to keep their therapeutic properties. There are presently no official guidelines for testing pharmaceutical products in order to define suitable transport specifications. After reviewing the current guidance documents, this paper proposes a methodology for testing pharmaceutical products and defining appropriate transport conditions.

Mold Heating and Cooling Pump Package Operator Interface Controls Upgrade

DOE Office of Scientific and Technical Information (OSTI.GOV)

Josh A. Salmond

2009-08-07

The modernization of the Mold Heating and Cooling Pump Package Operator Interface (MHC PP OI) consisted of upgrading the antiquated single board computer with a proprietary operating system to off-the-shelf hardware and off-the-shelf software with customizable software options. The pump package is the machine interface between a central heating and cooling system that pumps heat transfer fluid through an injection or compression mold base on a local plastic molding machine. The operator interface provides the intelligent means of controlling this pumping process. Strict temperature control of a mold allows the production of high quality parts with tight tolerances and lowmore » residual stresses. The products fabricated are used on multiple programs.« less

Winter Simulation Conference, Miami Beach, Fla., December 4-6, 1978, Proceedings. Volumes 1 & 2

NASA Technical Reports Server (NTRS)

Highland, H. J. (Editor); Nielsen, N. R.; Hull, L. G.

1978-01-01

The papers report on the various aspects of simulation such as random variate generation, simulation optimization, ranking and selection of alternatives, model management, documentation, data bases, and instructional methods. Simulation studies in a wide variety of fields are described, including system design and scheduling, government and social systems, agriculture, computer systems, the military, transportation, corporate planning, ecosystems, health care, manufacturing and industrial systems, computer networks, education, energy, production planning and control, financial models, behavioral models, information systems, and inventory control.

Automated electric power management and control for Space Station Freedom

NASA Technical Reports Server (NTRS)

Dolce, James L.; Mellor, Pamela A.; Kish, James A.

1990-01-01

A comprehensive automation design is being developed for Space Station Freedom's electric power system. It strives to increase station productivity by applying expert systems and conventional algorithms to automate power system operation. An integrated approach to the power system command and control problem is defined and used to direct technology development in: diagnosis, security monitoring and analysis, battery management, and cooperative problem-solving for resource allocation. The prototype automated power system is developed using simulations and test-beds.

Radical is Temporary

NASA Technical Reports Server (NTRS)

Barrett, Larry

2004-01-01

I suspect that even if Ken had stayed on, we would have evolved to the state we're in right now. In terms of the nature of the work that we're doing, we've gone from development to maintenance, and so the project team needed to evolve to reflect that change. The analogy I use to describe Hubble is a data factory, and we provide the factory controller. The telescope takes in light and produces pictures, and we're the ones sending all of the control signals and monitoring the temperature, power, and voltages in the factory to make sure the production line is doing its job and that it's not reaching some sort of a stress point. That's basically it. We maintain the Hubble command and control system. I think we're still putting out a good quality product. We still meet our schedule and cost milestones. Every time we make a change to the ground system, we run a suite of tests to make sure that the system still runs as expected, and that it correctly controls the spacecraft. Other than that, provided the interfaces are controlled, everything is okay.

Inventory development for perfluorooctane sulfonic acid (PFOS) in Turkey: challenges to control chemicals in articles and products.

PubMed

Korucu, M Kemal; Gedik, Kadir; Weber, Roland; Karademir, Aykan; Kurt-Karakus, Perihan Binnur

2015-10-01

Perfluorooctane sulfonic acid (PFOS) and related substances have been listed as persistent organic pollutants (POPs) in the Stockholm Convention. Countries which have ratified the Convention need to take appropriate actions to control PFOS use and release. This study compiles and enhances the findings of the first inventory of PFOS and related substances use in Turkey conducted within the frame of the Stockholm Convention National Implementation Plan (NIP) update. The specific Harmonized Commodity Description and Coding System (Harmonized System (HS)) codes of imported and exported goods that possibly contain PFOS and 165 of Chemical Abstracts Service (CAS) numbers of PFOS-related substances were assessed for acquiring information from customs and other authorities. However, with the current approaches available, no useful information could be compiled since HS codes are not specific enough and CAS numbers are not used by customs. Furthermore, the cut-off volume in chemical databases in Turkey and the reporting limit in the HS system (0.1 %) are too high for controlling PFOS. The attempt of modeling imported volumes by a Monte Carlo simulation did not also result in a satisfactory estimate, giving an upper-bound estimate above the global production volumes. The replies to questionnaires were not satisfactory, highlighting that an elaborated approach is needed in the communication with potentially PFOS-using stakeholders. The experience of the challenges of gathering information on PFOS in articles and products revealed the gaps of controlling highly hazardous substances in products and articles and the need of improvements.

Expert systems for automated maintenance of a Mars oxygen production system

NASA Technical Reports Server (NTRS)

Ash, Robert L.; Huang, Jen-Kuang; Ho, Ming-Tsang

1989-01-01

A prototype expert system was developed for maintaining autonomous operation of a Mars oxygen production system. Normal operation conditions and failure modes according to certain desired criteria are tested and identified. Several schemes for failure detection and isolation using forward chaining, backward chaining, knowledge-based and rule-based are devised to perform several housekeeping functions. These functions include self-health checkout, an emergency shut down program, fault detection and conventional control activities. An effort was made to derive the dynamic model of the system using Bond-Graph technique in order to develop the model-based failure detection and isolation scheme by estimation method. Finally, computer simulations and experimental results demonstrated the feasibility of the expert system and a preliminary reliability analysis for the oxygen production system is also provided.

Systems Biology of Recombinant Protein Production in Bacillus megaterium

NASA Astrophysics Data System (ADS)

Biedendieck, Rebekka; Bunk, Boyke; Fürch, Tobias; Franco-Lara, Ezequiel; Jahn, Martina; Jahn, Dieter

Over the last two decades the Gram-positive bacterium Bacillus megaterium was systematically developed to a useful alternative protein production host. Multiple vector systems for high yield intra- and extracellular protein production were constructed. Strong inducible promoters were combined with DNA sequences for optimised ribosome binding sites, various leader peptides for protein export and N- as well as C-terminal affinity tags for affinity chromatographic purification of the desired protein. High cell density cultivation and recombinant protein production were successfully tested. For further system biology based control and optimisation of the production process the genomes of two B. megaterium strains were completely elucidated, DNA arrays designed, proteome, fluxome and metabolome analyses performed and all data integrated using the bioinformatics platform MEGABAC. Now, solid theoretical and experimental bases for primary modeling attempts of the production process are available.

System diagnostic builder: a rule-generation tool for expert systems that do intelligent data evaluation

NASA Astrophysics Data System (ADS)

Nieten, Joseph L.; Burke, Roger

1993-03-01

The system diagnostic builder (SDB) is an automated knowledge acquisition tool using state- of-the-art artificial intelligence (AI) technologies. The SDB uses an inductive machine learning technique to generate rules from data sets that are classified by a subject matter expert (SME). Thus, data is captured from the subject system, classified by an expert, and used to drive the rule generation process. These rule-bases are used to represent the observable behavior of the subject system, and to represent knowledge about this system. The rule-bases can be used in any knowledge based system which monitors or controls a physical system or simulation. The SDB has demonstrated the utility of using inductive machine learning technology to generate reliable knowledge bases. In fact, we have discovered that the knowledge captured by the SDB can be used in any number of applications. For example, the knowledge bases captured from the SMS can be used as black box simulations by intelligent computer aided training devices. We can also use the SDB to construct knowledge bases for the process control industry, such as chemical production, or oil and gas production. These knowledge bases can be used in automated advisory systems to ensure safety, productivity, and consistency.

Multi-kanban mechanism for appliance disassembly

NASA Astrophysics Data System (ADS)

Udomsawat, Gun; Gupta, Surendra M.

2005-11-01

The use of household appliances continues to rise every year. A significant number of End-Of-Life (EOL) appliances are generated because of the introduction of newer models that are more attractive, efficient and affordable. Others are, of course, generated when they become non-functional. Many regulations encourage recycling of EOL appliances to reduce the amount of waste sent to landfills. In addition, EOL appliances offer the appliance manufacturing and remanufacturing industries a source of less expensive raw materials and components. For this reason product recovery has become a subject of interest during the past decade. In this paper, we study the disassembly line for appliance disassembly. We discuss and incorporate some of the complications that are inherent in disassembly line including product arrival, demand arrival, inventory fluctuation and production control mechanisms. We show how to overcome such complications by implementing a multi-kanban system in the appliance disassembly line setting. The multi-kanban system (MKS) relies on dynamic routing of kanbans according to the state of the system. We investigate the multi-kanban mechanism using simulation and explore the effect of product mix on performance of the traditional push system (TPS) and MKS in terms of controlling the system's inventory while attempting to achieve a decent customer service level.

Advanced automation in space shuttle mission control

NASA Technical Reports Server (NTRS)

Heindel, Troy A.; Rasmussen, Arthur N.; Mcfarland, Robert Z.

1991-01-01

The Real Time Data System (RTDS) Project was undertaken in 1987 to introduce new concepts and technologies for advanced automation into the Mission Control Center environment at NASA's Johnson Space Center. The project's emphasis is on producing advanced near-operational prototype systems that are developed using a rapid, interactive method and are used by flight controllers during actual Shuttle missions. In most cases the prototype applications have been of such quality and utility that they have been converted to production status. A key ingredient has been an integrated team of software engineers and flight controllers working together to quickly evolve the demonstration systems.

Base Stock Policy in a Join-Type Production Line with Advanced Demand Information

NASA Astrophysics Data System (ADS)

Hiraiwa, Mikihiko; Tsubouchi, Satoshi; Nakade, Koichi

Production control such as the base stock policy, the kanban policy and the constant work-in-process policy in a serial production line has been studied by many researchers. Production lines, however, usually have fork-type, join-type or network-type figures. In addition, in most previous studies on production control, a finished product is required at the same time as arrival of demand at the system. Demand information is, however, informed before due date in practice. In this paper a join-type (assembly) production line under base stock control with advanced demand information in discrete time is analyzed. The recursive equations for the work-in-process are derived. The heuristic algorithm for finding appropriate base stock levels of all machines at short time is proposed and the effect of advanced demand information is examined by simulation with the proposed algorithm. It is shown that the inventory cost can decreases with little backlogs by using the appropriate amount of demand information and setting appropriate base stock levels.

Engineering Escherichia coli for high-yield geraniol production with biotransformation of geranyl acetate to geraniol under fed-batch culture.

PubMed

Liu, Wei; Xu, Xin; Zhang, Rubing; Cheng, Tao; Cao, Yujin; Li, Xiaoxiao; Guo, Jiantao; Liu, Huizhou; Xian, Mo

2016-01-01

Geraniol is an acyclic monoterpene alcohol, which exhibits good prospect as a gasoline alternative. Geraniol is naturally encountered in plants at low concentrations and an attractive target for microbial engineering. Geraniol has been heterologously produced in Escherichia coli, but the low titer hinders its industrial applications. Moreover, bioconversion of geraniol by E. coli remains largely unknown. Recombinant overexpression of Ocimum basilicum geraniol synthase, Abies grandis geranyl diphosphate synthase, and a heterotic mevalonate pathway in E. coli BL21 (DE3) enabled the production of up to 68.6 ± 3 mg/L geraniol in shake flasks. Initial fed-batch fermentation only increased geraniol production to 78.8 mg/L. To further improve the production yield, the fermentation conditions were optimized. Firstly, 81.4 % of volatile geraniol was lost during the first 5 h of fermentation in a solvent-free system. Hence, isopropyl myristate was added to the culture medium to form an aqueous-organic two-phase culture system, which effectively prevented volatilization of geraniol. Secondly, most of geraniol was eventually biotransformed into geranyl acetate by E. coli, thus decreasing geraniol production. For the first time, we revealed the role of acetylesterase (Aes, EC 3.1.1.6) from E. coli in hydrolyzing geranyl acetate to geraniol, and production of geraniol was successfully increased to 2.0 g/L under controlled fermentation conditions. An efficient geraniol production platform was established by overexpressing several key pathway proteins in engineered E. coli strain combined with a controlled fermentation system. About 2.0 g/L geraniol was obtained using our controllable aqueous-organic two-phase fermentation system, which is the highest yield to date. In addition, the interconversion between geraniol and geranyl acetate by E. coli was first elucidated. This study provided a new and promising strategy for geraniol biosynthesis, which laid a basis for large-scale industrial application.

Ares I Flight Control System Overview

NASA Technical Reports Server (NTRS)

Hall, Charles; Lee, Chong; Jackson, Mark; Whorton, Mark; West, mark; Brandon, Jay; Hall, Rob A.; Jang, Jimmy; Bedrossian, Naz; Compton, Jimmy;

Structuring Formal Control Systems Specifications for Reuse: Surviving Hardware Changes

NASA Technical Reports Server (NTRS)

Thompson, Jeffrey M.; Heimdahl, Mats P. E.; Erickson, Debra M.

2000-01-01

Formal capture and analysis of the required behavior of control systems have many advantages. For instance, it encourages rigorous requirements analysis, the required behavior is unambiguously defined, and we can assure that various safety properties are satisfied. Formal modeling is, however, a costly and time consuming process and if one could reuse the formal models over a family of products, significant cost savings would be realized. In an ongoing project we are investigating how to structure state-based models to achieve a high level of reusability within product families. In this paper we discuss a high-level structure of requirements models that achieves reusability of the desired control behavior across varying hardware platforms in a product family. The structuring approach is demonstrated through a case study in the mobile robotics domain where the desired robot behavior is reused on two diverse platforms-one commercial mobile platform and one build in-house. We use our language RSML (-e) to capture the control behavior for reuse and our tool NIMBUS to demonstrate how the formal specification can be validated and used as a prototype on the two platforms.

Epi-fingerprinting and epi-interventions for improved crop production and food quality

PubMed Central

Rodríguez López, Carlos M.; Wilkinson, Mike J.

2015-01-01

Increasing crop production at a time of rapid climate change represents the greatest challenge facing contemporary agricultural research. Our understanding of the genetic control of yield derives from controlled field experiments designed to minimize environmental variance. In spite of these efforts there is substantial residual variability among plants attributable to Genotype × Environment interactions. Recent advances in the field of epigenetics have revealed a plethora of gene control mechanisms that could account for much of this unassigned variation. These systems act as a regulatory interface between the perception of the environment and associated alterations in gene expression. Direct intervention of epigenetic control systems hold the enticing promise of creating new sources of variability that could enhance crop performance. Equally, understanding the relationship between various epigenetic states and responses of the crop to specific aspects of the growing environment (epigenetic fingerprinting) could allow for a more tailored approach to plant agronomy. In this review, we explore the many ways in which epigenetic interventions and epigenetic fingerprinting can be deployed for the improvement of crop production and quality. PMID:26097484

Tank waste remediation system privatization infrastructure program, configuration management implementation plan

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schaus, P.S.

This Configuration Management Implementation Plan (CMIP) was developed to assist in managing systems, structures, and components (SSCS), to facilitate the effective control and statusing of changes to SSCS, and to ensure technical consistency between design, performance, and operational requirements. Its purpose is to describe the approach Privatization Infrastructure will take in implementing a configuration management program, to identify the Program`s products that need configuration management control, to determine the rigor of control, and to identify the mechanisms for that control.

Development of HIDEC adaptive engine control systems

NASA Technical Reports Server (NTRS)

Landy, R. J.; Yonke, W. A.; Stewart, J. F.

1986-01-01

The purpose of NASA's Highly Integrated Digital Electronic Control (HIDEC) flight research program is the development of integrated flight propulsion control modes, and the evaluation of their benefits aboard an F-15 test aircraft. HIDEC program phases are discussed, with attention to the Adaptive Engine Control System (ADECS I); this involves the upgrading of PW1128 engines for operation at higher engine pressure ratios and the production of greater thrust. ADECS II will involve the development of a constant thrust mode which will significantly reduce turbine operating temperatures.

40 CFR 63.11140 - Am I subject to this subpart?

Code of Federal Regulations, 2014 CFR

2014-07-01

... copolymers production affected source is the facility-wide collection of PVCPU, storage vessels, heat exchange systems, surge control vessels, and wastewater and process wastewater treatment systems that are...

40 CFR 63.11140 - Am I subject to this subpart?

Code of Federal Regulations, 2013 CFR

2013-07-01

... copolymers production affected source is the facility-wide collection of PVCPU, storage vessels, heat exchange systems, surge control vessels, and wastewater and process wastewater treatment systems that are...