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Sample records for production iii testing

  1. Antithrombin III blood test

    MedlinePlus

    ... be due to: Bone marrow transplant Disseminated intravascular coagulation (DIC) AT III deficiency, an inherited condition Liver ... Schmaier AH, Miller JL. Coagulation and fibrinolysis. In: McPherson ... Management by Laboratory Methods . 22nd ed. Philadelphia, PA: ...

  2. Test Pool Questions, Area III.

    ERIC Educational Resources Information Center

    Sloan, Jamee Reid

    This manual contains multiple choice questions to be used in testing students on nurse training objectives. Each test includes several questions covering each concept. The concepts in section A, medical surgical nursing, are diseases of the following systems: musculoskeletal; central nervous; cardiovascular; gastrointestinal; urinary and male…

  3. Psychometric Testing of the FACES III with Rural Adolescents

    ERIC Educational Resources Information Center

    Ide, Bette; Dingmann, Colleen; Cuevas, Elizabeth; Meehan, Maurita

    2010-01-01

    This study tests the validity and reliability of the Family Adaptability and Cohesion Scale III (FACES III) in two samples of rural adolescents. The underlying theory is the linear 3-D circumplex model. The FACES III was administered to 1,632 adolescents in Grades 7 through 12 in two counties in a rural western state. The FACES III Scale and the…

  4. EXCEDE technology development III: first vacuum tests

    NASA Astrophysics Data System (ADS)

    Belikov, Ruslan; Lozi, Julien; Pluzhnik, Eugene; Hix, Troy T.; Bendek, Eduardo; Thomas, Sandrine J.; Lynch, Dana H.; Mihara, Roger; Irwin, J. Wes; Duncan, Alan L.; Greene, Thomas P.; Guyon, Olivier; Kendrick, Richard L.; Smith, Eric H.; Witteborn, Fred C.; Schneider, Glenn

    2014-08-01

    This paper is the third in the series on the technology development for the EXCEDE (EXoplanetary Circumstellar Environments and Disk Explorer) mission concept, which in 2011 was selected by NASA's Explorer program for technology development (Category III). EXCEDE is a 0.7m space telescope concept designed to achieve raw contrasts of 1e6 at an inner working angle of 1.2 l/D and 1e7 at 2 l/D and beyond. This will allow it to directly detect and spatially resolve low surface brightness circumstellar debris disks as well as image giant planets as close as in the habitable zones of their host stars. In addition to doing fundamental science on debris disks, EXCEDE will also serve as a technological and scientific precursor for any future exo-Earth imaging mission. EXCEDE uses a Starlight Suppression System (SSS) based on the PIAA coronagraph, enabling aggressive performance. Previously, we reported on the achievement of our first milestone (demonstration of EXCEDE IWA and contrast in monochromatic light) in air. In this presentation, we report on our continuing progress of developing the SSS for EXCEDE, and in particular (a) the reconfiguration of our system into a more flight-like layout, with an upstream deformable mirror and an inverse PIAA system, and (b) testing this system in a vacuum chamber, including IWA, contrast, and stability performance. Even though this technology development is primarily targeted towards EXCEDE, it is also germane to any exoplanet direct imaging space-based telescopes because of the many challenges common to different coronagraph architectures and mission requirements. This work was supported in part by the NASA Explorer program and Ames Research Center, University of Arizona, and Lockheed Martin SSC.

  5. Suppressors of superoxide production from mitochondrial complex III.

    PubMed

    Orr, Adam L; Vargas, Leonardo; Turk, Carolina N; Baaten, Janine E; Matzen, Jason T; Dardov, Victoria J; Attle, Stephen J; Li, Jing; Quackenbush, Douglas C; Goncalves, Renata L S; Perevoshchikova, Irina V; Petrassi, H Michael; Meeusen, Shelly L; Ainscow, Edward K; Brand, Martin D

    2015-11-01

    Mitochondrial electron transport drives ATP synthesis but also generates reactive oxygen species, which are both cellular signals and damaging oxidants. Superoxide production by respiratory complex III is implicated in diverse signaling events and pathologies, but its role remains controversial. Using high-throughput screening, we identified compounds that selectively eliminate superoxide production by complex III without altering oxidative phosphorylation; they modulate retrograde signaling including cellular responses to hypoxic and oxidative stress.

  6. Suppressors of superoxide production from mitochondrial complex III

    PubMed Central

    Orr, Adam L.; Vargas, Leonardo; Turk, Carolina N.; Baaten, Janine E.; Matzen, Jason T.; Dardov, Victoria J.; Attle, Stephen J.; Li, Jing; Quackenbush, Douglas C.; Goncalves, Renata L. S.; Perevoshchikova, Irina V.; Petrassi, H. Michael; Meeusen, Shelly L.; Ainscow, Edward K.; Brand, Martin D.

    2015-01-01

    Mitochondrial electron transport drives ATP synthesis but also generates reactive oxygen species (ROS), which are both cellular signals and damaging oxidants. Superoxide production by respiratory complex III is implicated in diverse signaling events and pathologies but its role remains controversial. Using high-throughput screening we identified compounds that selectively eliminate superoxide production by complex III without altering oxidative phosphorylation; they modulate retrograde signaling including cellular responses to hypoxic and oxidative stress. PMID:26368590

  7. Ford Aerospace High-G Test Series II and III

    SciTech Connect

    Beshears, D.L.

    1987-03-01

    A series of tests is being conducted on electronic and optical components and assemblies to determine how well they operate after periods of constant high acceleration. This testing is being performed for the Ford Aerospace and Communications Corporation in support of the Air Force Space and Technology Center Sagittar Program. This final report documents the second and third series of tests which consisted of 47 test runs. The tests included the evaluation of some packaging techniques in an effort to extend the load capacity of a Panasonic lithium battery. Other tests conducted in Series II consisted of accelerating two receiver units (one with a gallium arsenide lens and the other with a zinc sulfide lens) to various G levels up to 120,281 G's. The qualification target for each of these units is 120,000 G's. In Test Series III, it was possible to further extend the Panasonic lithium battery life by not only encapsulating the battery in Castolite plastic, but also enclosing the entire assembly in an aluminum housing. The other components tested in Test Series III included two receiver units (one with a germanium lens and the other a 19-mm Kodak zinc sulfide lens), a 40-mm hybrid controller, a zinc sulfide lens assembly, an Altus lithium battery, a germanium filter, and two detectors. The qualification target for the 2 batteries and the 40-mm hybrid controller is 120,000 G's, while the qualification target for each of the other components tested in Series III is 140,000 G's.

  8. The Mark III vertex chamber and prototype test results

    SciTech Connect

    Grab, C.

    1987-07-01

    A vertex chamber has been constructed for use in the Mark III experiment. The chamber is positioned inside the current main drift chamber and will be used to trigger data collection, to aid in vertex reconstruction, and to improve the momentum resolution. This paper discusses the chamber's construction and performance and tests of the prototype.

  9. Product Module Rig Test

    NASA Technical Reports Server (NTRS)

    Holdeman, James D. (Technical Monitor); Chiappetta, Louis, Jr.; Hautman, Donald J.; Ols, John T.; Padget, Frederick C., IV; Peschke, William O. T.; Shirley, John A.; Siskind, Kenneth S.

    2004-01-01

    The low emissions potential of a Rich-Quench-Lean (RQL) combustor for use in the High Speed Civil Transport (HSCT) application was evaluated as part of Work Breakdown Structure (WBS) 1.0.2.7 of the NASA Critical Propulsion Components (CPC) Program under Contract NAS3-27235. Combustion testing was conducted in cell 1E of the Jet Burner Test Stand at United Technologies Research Center. Specifically, a Rich-Quench-Lean combustor, utilizing reduced scale quench technology implemented in a quench vane concept in a product-like configuration (Product Module Rig), demonstrated the capability of achieving an emissions index of nitrogen oxides (NOx EI) of 8.5 gm/Kg fuel at the supersonic flight condition (relative to the program goal of 5 gm/Kg fuel). Developmental parametric testing of various quench vane configurations in the more fundamental flametube, Single Module Rig Configuration, demonstrated NOx EI as low as 5.2. All configurations in both the Product Module Rig configuration and the Single Module Rig configuration demonstrated exceptional efficiencies, greater than 99.95 percent, relative to the program goal of 99.9 percent efficiency at supersonic cruise conditions. Sensitivity of emissions to quench orifice design parameters were determined during the parametric quench vane test series in support of the design of the Product Module Rig configuration. For the rectangular quench orifices investigated, an aspect ratio (length/width) of approximately 2 was found to be near optimum. An optimum for orifice spacing was found to exist at approximately 0.167 inches, resulting in 24 orifices per side of a quench vane, for the 0.435 inch quench zone channel height investigated in the Single Module Rig. Smaller quench zone channel heights appeared to be beneficial in reducing emissions. Measurements were also obtained in the Single Module Rig configuration on the sensitivity of emissions to the critical combustor parameters of fuel/air ratio, pressure drop, and residence

  10. GOES Type III Loop Heat Pipe Life Test Results

    NASA Technical Reports Server (NTRS)

    Ottenstein, Laura

    2011-01-01

    The GOES Type III Loop Heat Pipe (LHP) was built as a life test unit for the loop heat pipes on the GOES N-Q series satellites. This propylene LHP was built by Dynatherm Corporation in 2000 and tested continuously for approximately 14 months. It was then put into storage for 3 years. Following the storage period, the LHP was tested at Swales Aerospace to verify that the loop performance hadn t changed. Most test results were consistent with earlier results. At the conclusion of testing at Swales, the LHP was transferred to NASA/GSFC for continued periodic testing. The LHP has been set up for testing in the Thermal Lab at GSFC since 2006. A group of tests consisting of start-ups, power cycles, and a heat transport limit test have been performed every six to nine months since March 2006. Tests results have shown no change in the loop performance over the five years of testing. This presentation will discuss the test hardware, test set-up, and tests performed. Test results to be presented include sample plots from individual tests, along with conductance measurements for all tests performed.

  11. 21 CFR 866.5440 - Beta-2-glycoprotein III immunological test system.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Beta-2-glycoprotein III immunological test system....5440 Beta-2-glycoprotein III immunological test system. (a) Identification. A beta-2-glycoprotein III... the beta-2-glycoprotein III (a serum protein) in serum and other body fluids. Measurement of...

  12. 21 CFR 866.5440 - Beta-2-glycoprotein III immunological test system.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Beta-2-glycoprotein III immunological test system....5440 Beta-2-glycoprotein III immunological test system. (a) Identification. A beta-2-glycoprotein III... the beta-2-glycoprotein III (a serum protein) in serum and other body fluids. Measurement of...

  13. Fission product separations testing

    SciTech Connect

    Bostick, D.A.; DePaoli, S.M.

    1997-10-01

    The initial goal of this task is to adequately understand the treatment needs of the end user in treating contaminated wastewater. These needs are then incorporated into the evaluation of new treatment technologies for wastewater treatment. Pertinent information is than supplied to the end user so that they can select a preferred process to meet their waste treatment needs. New sorbent materials, ion-exchange materials, or other processes of interest to DOE`s Office of Environmental Restoration (EM-40) will be evaluated initially for the removal of {sup 90}Sr and {sup 137}Cs from groundwater and process wastewater. Laboratory studies will strive to obtain a quantitative understanding of the behavior of these new materials and to evaluate their sorption efficiency in reference to a standard benchmark treatment technique. Testing of the new materials will begin by conducting scoping tests where new treatment materials are compared with standard, commercially available materials in batch shaker tests. Experimental data for the most promising sorbents will then be fit to an equilibrium model so that nuclide sorption can be predicted for variable wastewater composition. Additional testing with actual wastewater will be conducted with two or three of the most effective treatment methods. Once batch testing of a treatment method is completed, dynamic column tests will be performed to validate the equilibrium sorption model and to obtain the defining column operating parameters for scaling up the technology.

  14. PRODUCTION VERIFICATION TESTS

    SciTech Connect

    Raymond L. Mazza

    2003-09-30

    A summary of the demonstration of 14 stages (in 10 wells) of a unique liquid-free stimulation process which employs carbon dioxide (CO{sub 2}) as the working fluid in ten Candidate Wells. Three were situated in Perry County and seven in Pike County of eastern kentucky's Big Sandy gas field. These activities included four individual efforts which have previously been described in detail in four submitted Final Reports, and are herein summarized. These ten Candidate wells produce from the Devonian Shale which is well known to be damaged by liquid based stimulation processes. They were treated with a total of fourteen stages; four as a single stage, and the others in two stages per well all containing approximately 120 tons of CO{sub 2} per stage. These liquid free stimulations also contained proppant quantities on the order of 45,000 lbs per stage. The results show in the three Perry Co Candidate wells that the stimulations were not as effective as the best conventional technology, and resulted in a stimulation cost for produced gas of $0.69 per Mcf vs $0.43 for N{sub 2} gas stimulations. The results in the Pike County Candidates, where the shale section is thicker--1,025 vs. 350 feet, indicated a superior response from the wells stimulated with the CO{sub 2}/sand process. A five year production benefit of 67.7 MMcf per stage, or 135.4 MMcf per well over that from the closest competing technology which results in a 3.41 benefit ratio and a stimulation cost for produced gas of $0.47 per Mcf vs $1.14 for N{sub 2} gas.

  15. ROLE OF IRON (II, III) HYDROXYCARBONATE GREEN RUST IN ARSENIC REMEDIATION USING ZEROVALENT IRON IN COLUMN TESTS

    EPA Science Inventory

    We examined corrosion products of zerovalent iron (Peerless iron) that was used in three column tests for removing arsenic under dynamic flow conditions with and without added phosphate and silicate. Iron(II, III) hydroxycarbonate and magnetite were major iron corrosion products...

  16. Testing of full size high current superconductors in SULTAN III

    SciTech Connect

    Blau, B.; Rohleder, I.; Vecsey, G.

    1994-07-01

    The high field test facility SULTAN III in operation at PSI/Switzerland tests full size industrial prototype superconductors for fusion applications such as ITER. The facility provides a background field of up to 11 T over a length of 58 cm. A 50 kA superconducting transformer works as a very low noise current source which allows a criterion of 0.1 {mu}V/cm to determine the superconducting to normal transition. Three 3.6 m long cable-in-conduit conductors based on both NbTi and Nb{sub 3}Sn, developed by different manufacturers, suitable for the central solenoid and toroidal field coils of ITER, have been tested so far. This paper presents the results of extensive measurements of critical current and current sharing temperature of the Nb{sub 3}Sn conductors in the 8--11 T range for temperatures between 4.5 K and 11 K Voltage versus current curves have been analyzed with respect to the n value. The manufacturing of a high quality joint between two Nb{sub 3}Sn conductors after heat treatment is reported, together with some measurements of the joint resistance.

  17. Tobacco and Nicotine Product Testing

    PubMed Central

    Biener, Lois; Leischow, Scott J.; Zeller, Mitch R.

    2012-01-01

    Introduction: Tobacco product testing is a critical component of the Family Smoking Prevention and Tobacco Control Act (FSPTCA), which grants the Food and Drug Administration the authority to regulate tobacco products. The availability of methods and measures that can provide accurate data on the relative health risks across types of tobacco products, brands, and subbrands of tobacco products on the validity of any health claims associated with a product, and on how consumers perceive information on products toxicity or risks is crucial for making decisions on the product's potential impact on public health. These tools are also necessary for making assessments of the impact of new indications for medicinal products (other than cessation) but more importantly of tobacco products that may in the future be marketed as cessation tools. Objective: To identify research opportunities to develop empirically based and comprehensive methods and measures for testing tobacco and other nicotine-containing products so that the best science is available when decisions are made about products or policies. Methods: Literature was reviewed to address sections of the FSPTCA relevant to tobacco product evaluation; research questions were generated and then reviewed by a committee of research experts. Results: A research agenda was developed for tobacco product evaluation in the general areas of toxicity and health risks, abuse liability, consumer perception, and population effects. Conclusion: A cohesive, systematic, and comprehensive assessment of tobacco products is important and will require building consensus and addressing some crucial research questions. PMID:21460383

  18. Mapping regions of the cauliflower mosaic virus ORF III product required for infectivity.

    PubMed

    Jacquot, E; Geldreich, A; Keller, M; Yot, P

    1998-03-15

    The open reading frame (ORF) III product (PIII) of the pararetrovirus cauliflower mosaic virus (CaMV) has nucleic acid-binding properties in vitro, but its biological role is not yet determined. ORF III is closely linked to ORF II and overlaps ORF IV out of frame in the CaMV genome. A new CaMV-derived vector (Ca delta) devoid of ORF III and containing unique restriction sites between ORFs II and IV was designed. Introduction of the wild-type CaMV ORF III into Ca delta results in a clone (Ca3) infectious in turnip plants. Truncated or point-mutated versions of ORF III were then inserted into Ca delta and tested in vivo. Inoculation of the different mutants into turnip revealed that the four C-terminal amino acid residues of PIII are dispensable for infectivity as well as an internal domain (amino acids 61 to 80). Taken together the results show that PIII possesses a functional two-domain organization. Moreover, the CaMV PIII function(s) cannot be replaced either by the PIII protein of another caulimovirus, the figwort mosaic virus, or by the P2 protein of the cacao swollen shoot badnavirus, a member of the second plant pararetrovirus group.

  19. Individualized Testing System: Performance Objectives, ISCS Level III.

    ERIC Educational Resources Information Center

    Hathway, James A., Ed.

    This is one of four major subdivisions of a set of individualized evaluation material for Level III of the Intermediate Science Curriculum Study (ISCS) developed as a part of the ISCS Individualized Teacher Preparation (ITP) program. The manual contains a composite list of selected measurable objectives of Level III of the ISCS program. It is…

  20. Production Hydraulic Packer Field Test

    SciTech Connect

    Schneller, Tricia; Salas, Jose

    2000-06-30

    In October 1999, the Rocky Mountain Oilfield Testing Center and Halliburton Energy Services cooperated on a field test of Halliburton's new Production Hydraulic Packer technology on Well 46-TPX-10 at Naval Petroleum Reserve No. 3 near Casper, WY. Performance of the packer was evaluated in set and unset operations. The packer's ability to seal the annulus between the casing and tubing was hydraulically tested and the results were recorded.

  1. Scaled Vitrification System III (SVS III) Process Development and Laboratory Tests at the West Valley Demonstration Project

    SciTech Connect

    V. Jain; S. M. Barnes; B. G. Bindi; R. A. Palmer

    2000-04-30

    At the West Valley Demonstration Project (WVDP),the Vitrification Facility (VF)is designed to convert the high-level radioactive waste (HLW)stored on the site to a stable glass for disposal at a Department of Energy (DOE)-specified federal repository. The Scaled Vitrification System III (SVS-III)verification tests were conducted between February 1995 and August 1995 as a supplemental means to support the vitrification process flowsheet, but at only one seventh the scale.During these tests,the process flowsheet was refined and optimized. The SVS-III test series was conducted with a focus on confirming the applicability of the Redox Forecasting Model, which was based on the Index of Feed Oxidation (IFO)developed during the Functional and Checkout Testing of Systems (FACTS)and SVS-I tests. Additional goals were to investigate the prototypical feed preparation cycle and test the new target glass composition. Included in this report are the basis and current designs of the major components of the Scale Vitrification System and the results of the SVS-III tests.The major subsystems described are the feed preparation and delivery, melter, and off-gas treatment systems. In addition,the correlation between the melter's operation and its various parameters;which included feed rate,cold cap coverage,oxygen reduction (redox)state of the glass,melter power,plenum temperature,and airlift analysis;were developed.

  2. Consumer oriented product noise testing

    NASA Astrophysics Data System (ADS)

    Blomberg, Les

    2005-09-01

    This paper explores the need for product noise measurements and how best to meet that need in the near future. Currently there is only a small market place for quieter consumer products. This is not because of lack of interest. No one really wants to announce to everyone in their house that they just flushed the toilet, few really want the entire neighborhood to know they are mowing their yard, etc. The small market place is primarily due to a lack of regulations on product noise, a lack of information easily available to consumers about which products are quieter, and market consolidation resulting in fewer manufacturers, most of whom are unwilling to emphasize their quieter products at the risk of eroding sales of their noisier ones (that currently have greater market share). In the absence of the EPA fulfilling its statutory requirement to regulate and label product noise under the Noise Control Act of 1972, and with the unwillingness of most industries to voluntarily publish accurate product noise data, there is a significant role for ``Consumer Oriented Product Noise Testing.'' This paper explores the Noise Pollution Clearinghouse's ongoing and planned product noise testing, evaluating its advantages, disadvantages, and limitations.

  3. 49 CFR 173.468 - Test for LSA-III material.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... measured following the 7 day immersion test and must not exceed 0.1 A2. ... 49 Transportation 2 2011-10-01 2011-10-01 false Test for LSA-III material. 173.468 Section 173.468... SHIPMENTS AND PACKAGINGS Class 7 (Radioactive) Materials § 173.468 Test for LSA-III material. (a)...

  4. Co-norming the WAIS-III and WMS-III: Is there a test-order effect on IQ and memory scores?

    PubMed

    Zhu, J; Tulsky, D S

    2000-11-01

    Test-order effect on the WAIS-III and WMS-III scores was evaluated using the WMS-III standardization sample. Participants completed the standardization editions of the WAIS-III and WMS-III in one session, with the tests administered in roughly counterbalanced order. Repeated measure MANOVA analyses were conducted to determine if there was an overall test-order effect for subtest, index, or IQ scores. No significant test-order effects were found for either the WAIS-III index or IQ scores or for the WMS-III index scores. At the subtest level, the majority of the WAIS-III and WMS-III subtests did not show a significant test-order effect. The exceptions were Digit Span and Digit Symbol-Coding on the WAIS-III and Faces II and Logical Memory II on the WMS-III. Although statistically significant test-order effects were found on these subtests, the effect sizes were small. This study indicates that the test-order effect is not a potential threat to the internal validity of the WAIS-III and WMS-III normative data. The practical implications of the current study are discussed.

  5. CO2 Washout Testing Using Various Inlet Vent Configurations in the Mark-III Space Suit

    NASA Technical Reports Server (NTRS)

    Korona, F. Adam; Norcross, Jason; Conger, Bruce; Navarro, Moses

    2014-01-01

    breathe freely. Oronasal ppCO2 will be monitored real-time via gas analyzers with sampling tubes connected to the oronasal mask. Metabolic rate will be calculated from the total oxygen consumption and CO2 production measured by additional gas analyzers at the air outlet from the suit. Real-time metabolic rate measurements will be used to adjust the treadmill workload to meet target metabolic rates. This paper provides detailed descriptions of the test hardware, methodology and results, as well as implications for future inlet vent design and ground testing in the Mark-III.

  6. Phase III (full scale) agitated mixing test plan

    SciTech Connect

    Ruff, D.T.

    1994-10-17

    Waste Receiving and Processing Facility Module 2A (WRAP 2A) is the proposed second module of the WRAP facility. This facility will provide the required treatment for contact Handled (CH) Low Level (LL) Mixed Waste (MW) to allow its permanent disposal. Solidification of a portion of this waste using a cement based grout has been selected in order to reduce the toxicity and mobility of the waste in the disposal site. Mixing of the waste with the cement paste and material handling constraints/requirements associated with the mixed material is, therefore, a key process in the overall treatment strategy. This test plan addresses Phase 3, Full Scale Testing. The objectives of these tests are to determine if there are scale-up issues associated with the mixing results obtained in Phase 1 and 2 mixing tests, verify the workability of mixtures resulting from previous formulation development efforts (Waste Immobilization Development [WID]), and provide a baseline for WRAP 2A mixing equipment design. To this end, the following objectives are of particular interest: determine geometric influence of mixing blade at full scale (i.e., size, type, and location: height/offset); determine if similar results in terms of mixing effectiveness and product quality are achievable at this scale; determine if vibration is as effective at this larger scale in fluidizing the mixture and aiding in cleaning the vessel; determine if baffles or sweeping blades are needed to aid in mixing at the larger size and for cleaning the vessel; and determine quality of the poured monolithic product and investigate exotherm and filling influences at this larger size.

  7. 30 CFR 57.22229 - Weekly testing (I-A, III, and V-A mines).

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Weekly testing (I-A, III, and V-A mines). 57.22229 Section 57.22229 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR...-A, III, and V-A mines). (a) The mine atmosphere shall be tested for methane and carbon monoxide...

  8. 30 CFR 57.22229 - Weekly testing (I-A, III, and V-A mines).

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Weekly testing (I-A, III, and V-A mines). 57.22229 Section 57.22229 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR...-A, III, and V-A mines). (a) The mine atmosphere shall be tested for methane and carbon monoxide...

  9. 30 CFR 57.22229 - Weekly testing (I-A, III, and V-A mines).

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Weekly testing (I-A, III, and V-A mines). 57.22229 Section 57.22229 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR...-A, III, and V-A mines). (a) The mine atmosphere shall be tested for methane and carbon monoxide...

  10. Determination of antibodies against LAV/HTLV III: comparative evaluation of four different commercial test kits.

    PubMed

    Abb, J

    1986-01-01

    Four different, commercially available ELISA tests for the detection of antibodies against LAV/HTLV III were evaluated for specificity and sensitivity. The relative specificity of the kits was determined by investigating a test panel of 76 sera collected from asymptomatic or symptomatic homosexual men. Completely concordant results were obtained for sera from asymptomatic male homosexuals (11% positive for Anti-LAV/HTLV III) or from patients with the AIDS-related complex (91% positive for Anti-LAV/HTLV III). Differences between the ELISA test kits, however, were observed with sera obtained from patients with AIDS. While Anti-LAV/HTLV III was detected by the Abbott, Electro-Nucleonics, and Organon test in all 17 sera from AIDS patients, the Pasteur test failed to detect Anti-LAV/HTLV III in 7 consecutive sera from an individual patient with late-stage AIDS. The relative sensitivity of the ELISA tests was determined by endpoint titration of confirmed Anti-LAV/HTLV III positive sera from donors of different risk groups for AIDS. The titration experiments demonstrated that the Abbott test clearly was the most sensitive of the ELISA tests studied, followed by the Electro-Nucleonics, Pasteur, and Organon test. The results further indicate that most of the differences of specificity and sensitivity observed between the Anti-LAV/HTLV III tests could be abolished by a modified definition of minimum positive absorbance values.

  11. 16 CFR 1204.16 - Production testing.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Production testing. 1204.16 Section 1204.16... STANDARD FOR OMNIDIRECTIONAL CITIZENS BAND BASE STATION ANTENNAS Certification § 1204.16 Production testing... production testing. Each production test shall be conducted at a production interval short enough to...

  12. 16 CFR 1212.16 - Production testing.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 16 Commercial Practices 2 2011-01-01 2011-01-01 false Production testing. 1212.16 Section 1212.16... STANDARD FOR MULTI-PURPOSE LIGHTERS Certification Requirements § 1212.16 Production testing. (a) General... determine the types of tests for production testing. Each production test shall be conducted at a...

  13. An Application of Graphical Approach to Construct Multiple Testing Procedures in a Hypothetical Phase III Design

    PubMed Central

    Wang, Bushi; Ting, Naitee

    2014-01-01

    Many multiple testing procedures (MTP) have been developed in recent years. Among these new procedures, the graphical approach is flexible and easy to communicate with non-statisticians. A hypothetical Phase III clinical trial design is introduced in this manuscript to demonstrate how graphical approach can be applied in clinical product development. In this design, an active comparator is used. It is thought that this test drug under development could potentially be superior to this comparator. For comparison of efficacy, the primary endpoint is well established and widely accepted by regulatory agencies. However, an important secondary endpoint based on Phase II findings looks very promising. The target dose may have a good opportunity to deliver superiority to the comparator. Furthermore, a lower dose is included in case the target dose may demonstrate potential safety concerns. This Phase III study is designed as a non-inferiority trial with two doses, and two endpoints. This manuscript will illustrate how graphical approach is applied to this design in handling multiple testing issues. PMID:24432299

  14. Integrated Investigation on the Production and Fate of Organo-Cr(III) Complexes from Microbial Reduction of Chromate

    SciTech Connect

    Xun, Luying

    2005-06-01

    Our objective is to investigate the complexity of chromium biogeocycling. Our results clearly support more complexity. In short, the chromium cycle is not as simple as the conversion between Cr(III) and Cr(VI) in inorganic forms. We have obtained more evidence to prove the formation of soluble organo-Cr(III) complexes from microbial reduction of Cr(VI). The complexes are relatively stable due to the slow ligand exchange of Cr(III). However, some microorganisms can consume the organic ligands and release Cr(III), which then precipitates. Efforts are being made to characterize the organo-Cr(III) complexes and investigate their behavior in soil. Progress and efforts are summarized for each task. Task 1. Production of soluble organo-Cr(III) complexes by selected microorganisms A total of eight organisms were screened for production of soluble organo-Cr(III) complexes by culturing in both growth and non growth media containing 4 mg/L of Cr(VI); three were Gram positive and five were Gram negative. The Gram-positive bacteria were Cellulomonas sp. ES 6, Rhodococcus sp., and Leafsonia sp., while Shewanella oneidensis MR 1, Desulfovibrio desulfuricans G20, D. vulgaris Hildenborough, Pseudomonas putida MK 1 and Ps. aeruginosa PAO 1 were Gram negative. Purifications of the soluble organo-Cr(III) complexes produced by Cellulomonas sp. ES 6, Shewanella. oneidensis MR 1, Rhodococcus sp., and D. vulgaris Hildenborough were carried out. The culture supernatants were lyophilized and extracted first with methanol followed by water. The extracts were then analyzed for soluble Cr. The majority of the Cr(III) was present in the water-soluble fraction for all of the bacteria tested (data not shown), revealing a general phenomenon of soluble Cr(III) production. Cellulomonas sp. ES6 produced the highest amount of soluble Cr(III) (364 ppm) and D. vulgaris Hildenborough produced the least (143 ppm). Seventy eight percent of the soluble Cr(III) produced by Shewanella. oneidensis MR 1 was

  15. Carbon Dioxide Washout Testing Using Various Inlet Vent Configurations in the Mark-III Space Suit

    NASA Technical Reports Server (NTRS)

    Korona, F. Adam; Norcross, Jason; Conger, Bruce; Navarro, Moses

    2014-01-01

    Requirements for using a space suit during ground testing include providing adequate carbon dioxide (CO2) washout for the suited subject. Acute CO2 exposure can lead to symptoms including headache, dyspnea, lethargy, and eventually unconsciousness or even death. Symptoms depend on several factors including inspired partial pressure of CO2 (ppCO2), duration of exposure, metabolic rate of the subject, and physiological differences between subjects. Computational Fluid Dynamics (CFD) analysis has predicted that the configuration of the suit inlet vent has a significant effect on oronasal CO2 concentrations. The main objective of this test was to characterize inspired oronasal ppCO2 for a variety of inlet vent configurations in the Mark-III suit across a range of workload and flow rates. Data and trends observed during testing along with refined CFD models will be used to help design an inlet vent configuration for the Z-2 space suit. The testing methodology used in this test builds upon past CO2 washout testing performed on the Z-1 suit, Rear Entry I-Suit, and the Enhanced Mobility Advanced Crew Escape Suit. Three subjects performed two test sessions each in the Mark-III suit to allow for comparison between tests. Six different helmet inlet vent configurations were evaluated during each test session. Suit pressure was maintained at 4.3 psid. Suited test subjects walked on a treadmill to generate metabolic workloads of approximately 2000 and 3000 BTU/hr. Supply airflow rates of 6 and 4 actual cubic feet per minute were tested at each workload. Subjects wore an oronasal mask with an open port in front of the mouth and were allowed to breathe freely. Oronasal ppCO2 was monitored real-time via gas analyzers with sampling tubes connected to the oronasal mask. Metabolic rate was calculated from the CO2 production measured by an additional gas analyzer at the air outlet from the suit. Real-time metabolic rate measurements were used to adjust the treadmill workload to meet

  16. CO2 Washout Testing Using Various Inlet Vent Configurations in the Mark-III Space Suit

    NASA Technical Reports Server (NTRS)

    Korona, F. Adam; Norcross, Jason; Conger, Bruce; Navarro, Moses

    2014-01-01

    Requirements for using a space suit during ground testing include providing adequate carbon dioxide (CO2) washout for the suited subject. Acute CO2 exposure can lead to symptoms including headache, dyspnea, lethargy and eventually unconsciousness or even death. Symptoms depend on several factors including inspired partial pressure of CO2 (ppCO2), duration of exposure, metabolic rate of the subject and physiological differences between subjects. Computational Fluid Dynamic (CFD) analysis has predicted that the configuration of the suit inlet vent has a significant effect on oronasal CO2 concentrations. The main objective of this test was to characterize inspired oronasal ppCO2 for a variety of inlet vent configurations in the Mark-III suit across a range of workload and flow rates. Data and trends observed during testing along with refined CFD models will be used to help design an inlet vent configuration for the Z-2 space suit. The testing methodology used in this test builds upon past CO2 washout testing performed on the Z-1 suit, Rear Entry I-Suit (REI) and the Enhanced Mobility Advanced Crew Escape Suit (EM-ACES). Three subjects performed two test sessions each in the Mark-III suit to allow for comparison between tests. Six different helmet inlet vent configurations were evaluated during each test session. Suit pressure was maintained at 4.3 psid. Suited test subjects walked on a treadmill to generate metabolic workloads of approximately 2000 and 3000 BTU/hr. Supply airflow rates of 6 and 4 actual cubic feet per minute (ACFM) were tested at each workload. Subjects wore an oronasal mask with an open port in front of the mouth and were allowed to breathe freely. Oronasal ppCO2 was monitored real-time via gas analyzers with sampling tubes connected to the oronasal mask. Metabolic rate was calculated from the total oxygen consumption and CO2 production measured by additional gas analyzers at the air outlet from the suit. Realtime metabolic rate measurements were

  17. CO2 Washout Testing Using Various Inlet Vent Configurations in the Mark-III Space Suit

    NASA Technical Reports Server (NTRS)

    Korona, F. Adam; Norcross, Jason; Conger, Bruce; Navarro, Moses

    2014-01-01

    Requirements for using a space suit during ground testing include providing adequate carbon dioxide (CO2) washout for the suited subject. Acute CO2 exposure can lead to symptoms including headache, dyspnea, lethargy and eventually unconsciousness or even death. Symptoms depend on several factors including inspired partial pressure of CO2 (ppCO2), duration of exposure, metabolic rate of the subject and physiological differences between subjects. Computational Fluid Dynamic (CFD) analysis has predicted that the configuration of the suit inlet vent has a significant effect on oronasal CO2 concentrations. The main objective of this test was to characterize inspired oronasal ppCO2 for a variety of inlet vent configurations in the Mark-III suit across a range of workload and flow rates. Data and trends observed during testing along with refined CFD models will be used to help design an inlet vent configuration for the Z-2 space suit. The testing methodology used in this test builds upon past CO2 washout testing performed on the Z-1 suit, Rear Entry I-Suit (REI) and the Enhanced Mobility Advanced Crew Escape Suit (EM-ACES). Three subjects performed two test sessions each in the Mark-III suit to allow for comparison between tests. Six different helmet inlet vent configurations were evaluated during each test session. Suit pressure was maintained at 4.3 psid. Suited test subjects walked on a treadmill to generate metabolic workloads of approximately 2000 and 3000 BTU/hr. Supply airflow rates of 6 and 4 actual cubic feet per minute (ACFM) were tested at each workload. Subjects wore an oronasal mask with an open port in front of the mouth and were allowed to breathe freely. Oronasal ppCO2 was monitored real-time via gas analyzers with sampling tubes connected to the oronasal mask. Metabolic rate was calculated from the total oxygen consumption and CO2 production measured by additional gas analyzers at the air outlet from the suit. Real-time metabolic rate measurements were

  18. A Testing Instrument for High School Arabic, Level III.

    ERIC Educational Resources Information Center

    Wolowelsky, Joel B.

    The Arabic language examination was designed for Jewish immigrants from Syria wishing to satisfy New York State language requirements for high school graduation by indicating their proficiency in Arabic. The test is essentially a translation of a state test of Hebrew, and is intended to test Arabic at the third-year high school level. The…

  19. Subsea production test valve assembly

    SciTech Connect

    Yates, P.D.

    1988-03-22

    In the subsea test assembly securable within a blowout preventer stack above a subterranean well and positionable between upper and lower portions of a tubular conduit in fluid communication with a production zone within the well, the test assembly is described including an upper subassembly carriable with the upper conduit portion, a lower subassembly carriable with the lower conduit portion, and valve means in the lower subassembly manipulatable between opened and closed positions to control fluid flow within the conduit. The improvement comprises: the upper subassembly including an upper housing and first rigid dog means fixedly secured to the upper housing; the lower subassembly including a lower housing and second rigid dog means fixedly secured to the lower housing; the first rigid dog means positionable between a latch position for latching the upper and lower subassemblies and an unlatch position for unlatching the upper and lower subassemblies upon rotational movement of the first dog means with respect to the second dog means; and lock means axially movable relative to the first and second dog means from a lock position for limiting rotational movement of the first dog means with respect to the second dog means to an unlock position for allowing the first dog means to rotate relative to the second dog means and unlatch the upper subassembly from the lower subassembly.

  20. The bone diagnostic instrument III: testing mouse femora.

    PubMed

    Randall, Connor; Mathews, Phillip; Yurtsev, Eugene; Sahar, Nadder; Kohn, David; Hansma, Paul

    2009-06-01

    Here we describe modifications that allow the bone diagnostic instrument (BDI) [P. Hansma et al., Rev. Sci. Instrum. 79, 064303 (2008); Rev. Sci. Instrum. 77, 075105 (2006)], developed to test human bone, to test the femora of mice. These modifications include reducing the effective weight of the instrument on the bone, designing and fabricating new probe assemblies to minimize damage to the small bone, developing new testing protocols that involve smaller testing forces, and fabricating a jig for securing the smaller bones for testing. With these modifications, the BDI was used to test the hypothesis that short-term running has greater benefit on the mechanical properties of the femur for young growing mice compared to older, skeletally mature mice. We measured elastic modulus, hardness, and indentation distance increase (IDI), which had previously been shown to be the best discriminators in model systems known to exhibit differences in mechanical properties at the whole bone level. In the young exercised murine femora, the IDI was significantly lower than in young control femora. Since IDI has a relation to postyield properties, these results suggest that exercise during bone development increases post yield mechanical competence. We were also able to measure effects of aging on bone properties with the BDI. There was a significant increase in the IDI, and a significant decrease in the elastic modulus and hardness between the young and old groups. Thus, with the modifications described here, the BDI can take measurements on mouse bones and obtain statistically significant results.

  1. Long maximal incremental tests accurately assess aerobic fitness in class II and III obese men.

    PubMed

    Lanzi, Stefano; Codecasa, Franco; Cornacchia, Mauro; Maestrini, Sabrina; Capodaglio, Paolo; Brunani, Amelia; Fanari, Paolo; Salvadori, Alberto; Malatesta, Davide

    2015-01-01

    This study aimed to compare two different maximal incremental tests with different time durations [a maximal incremental ramp test with a short time duration (8-12 min) (STest) and a maximal incremental test with a longer time duration (20-25 min) (LTest)] to investigate whether an LTest accurately assesses aerobic fitness in class II and III obese men. Twenty obese men (BMI≥35 kg.m-2) without secondary pathologies (mean±SE; 36.7±1.9 yr; 41.8±0.7 kg*m-2) completed an STest (warm-up: 40 W; increment: 20 W*min-1) and an LTest [warm-up: 20% of the peak power output (PPO) reached during the STest; increment: 10% PPO every 5 min until 70% PPO was reached or until the respiratory exchange ratio reached 1.0, followed by 15 W.min-1 until exhaustion] on a cycle-ergometer to assess the peak oxygen uptake [Formula: see text] and peak heart rate (HRpeak) of each test. There were no significant differences in [Formula: see text] (STest: 3.1±0.1 L*min-1; LTest: 3.0±0.1 L*min-1) and HRpeak (STest: 174±4 bpm; LTest: 173±4 bpm) between the two tests. Bland-Altman plot analyses showed good agreement and Pearson product-moment and intra-class correlation coefficients showed a strong correlation between [Formula: see text] (r=0.81 for both; p≤0.001) and HRpeak (r=0.95 for both; p≤0.001) during both tests. [Formula: see text] and HRpeak assessments were not compromised by test duration in class II and III obese men. Therefore, we suggest that the LTest is a feasible test that accurately assesses aerobic fitness and may allow for the exercise intensity prescription and individualization that will lead to improved therapeutic approaches in treating obesity and severe obesity.

  2. Testing and evaluation of a Hybrid III load sensing face.

    PubMed

    Planath, I; Nilsson, S

    1989-10-01

    To detect localized facial forces in laboratory car crash conditions, a load sensing face (LSF) was developed. Piezoelectric sensors provide pressure time histories. Design properties and characteristics of the LSF are described, as well as the sensor technique used. Sled tests with a LSF equipped dummy are presented. The purpose was to evaluate the efficiency of the method in registering facial impact magnitude and location with different restraint and seat position combinations. The LSF was also used in drop testing of steering wheels. Various impact velocities and impact points as well as the reapeatability were studied. PMID:2619857

  3. Division I Hockey Players Generate More Power Than Division III Players During on- and Off-Ice Performance Tests.

    PubMed

    Peterson, Ben J; Fitzgerald, John S; Dietz, Calvin C; Ziegler, Kevin S; Ingraham, Stacy J; Baker, Sarah E; Snyder, Eric M

    2015-05-01

    Current research has found anthropometric and physiological characteristics of hockey players that are correlated to performance. These characteristics, however, have never been examined to see whether significant differences exist between on- and off-ice performance markers at different levels of play; Division I, Elite Junior, and Division III. The purpose of this study was to examine the differences that may exist between these characteristics in Division I (24), Elite Junior (10), and Division III hockey (11) players. Forty-five (age: 18-24 years) hockey players completed anthropometric, on-ice, and off-ice tests to ascertain average measures for each division of play. On-ice testing was conducted in full hockey gear and consisted of acceleration, top-speed, and on-ice repeated shift test (RST). Off-ice tests included vertical jump, Wingate, grip strength, and a graded exercise test performed on a skating treadmill to ascertain their (Equation is included in full-text article.). Division I players had significantly lower body fat than their Division III peers (p = 0.004). Division I players also scored significantly better on measures of anaerobic power; vertical jump (p = 0.001), Wingate peak power (p = 0.05), grip strength (p = 0.008), top speed (p = 0.001), and fastest RST course time (p = 0.001) than their Division III counterparts. There was no significant difference between Division I and Elite Junior players for any on- or off-ice performance variable. The results of this study indicate that performance differences between Division I and Division III hockey players seem to be primarily because of the rate of force production.

  4. 16 CFR 1210.16 - Production testing.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 16 Commercial Practices 2 2013-01-01 2013-01-01 false Production testing. 1210.16 Section 1210.16 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION CONSUMER PRODUCT SAFETY ACT REGULATIONS SAFETY STANDARD FOR CIGARETTE LIGHTERS Certification Requirements § 1210.16 Production testing. (a)...

  5. 16 CFR 1210.16 - Production testing.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 16 Commercial Practices 2 2011-01-01 2011-01-01 false Production testing. 1210.16 Section 1210.16 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION CONSUMER PRODUCT SAFETY ACT REGULATIONS SAFETY STANDARD FOR CIGARETTE LIGHTERS Certification Requirements § 1210.16 Production testing. (a)...

  6. 16 CFR 1210.16 - Production testing.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Production testing. 1210.16 Section 1210.16 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION CONSUMER PRODUCT SAFETY ACT REGULATIONS SAFETY STANDARD FOR CIGARETTE LIGHTERS Certification Requirements § 1210.16 Production testing. (a)...

  7. 16 CFR 1212.16 - Production testing.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 16 Commercial Practices 2 2014-01-01 2014-01-01 false Production testing. 1212.16 Section 1212.16 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION CONSUMER PRODUCT SAFETY ACT REGULATIONS SAFETY STANDARD FOR MULTI-PURPOSE LIGHTERS Certification Requirements § 1212.16 Production testing. (a)...

  8. 16 CFR 1212.16 - Production testing.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 16 Commercial Practices 2 2012-01-01 2012-01-01 false Production testing. 1212.16 Section 1212.16 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION CONSUMER PRODUCT SAFETY ACT REGULATIONS SAFETY STANDARD FOR MULTI-PURPOSE LIGHTERS Certification Requirements § 1212.16 Production testing. (a)...

  9. 16 CFR 1212.16 - Production testing.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 16 Commercial Practices 2 2013-01-01 2013-01-01 false Production testing. 1212.16 Section 1212.16 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION CONSUMER PRODUCT SAFETY ACT REGULATIONS SAFETY STANDARD FOR MULTI-PURPOSE LIGHTERS Certification Requirements § 1212.16 Production testing. (a)...

  10. 16 CFR 1210.16 - Production testing.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 16 Commercial Practices 2 2014-01-01 2014-01-01 false Production testing. 1210.16 Section 1210.16 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION CONSUMER PRODUCT SAFETY ACT REGULATIONS SAFETY STANDARD FOR CIGARETTE LIGHTERS Certification Requirements § 1210.16 Production testing. (a)...

  11. 16 CFR 1210.16 - Production testing.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 16 Commercial Practices 2 2012-01-01 2012-01-01 false Production testing. 1210.16 Section 1210.16 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION CONSUMER PRODUCT SAFETY ACT REGULATIONS SAFETY STANDARD FOR CIGARETTE LIGHTERS Certification Requirements § 1210.16 Production testing. (a)...

  12. Latent Class Analysis of Differential Item Functioning on the Peabody Picture Vocabulary Test-III

    ERIC Educational Resources Information Center

    Webb, Mi-young Lee; Cohen, Allan S.; Schwanenflugel, Paula J.

    2008-01-01

    This study investigated the use of latent class analysis for the detection of differences in item functioning on the Peabody Picture Vocabulary Test-Third Edition (PPVT-III). A two-class solution for a latent class model appeared to be defined in part by ability because Class 1 was lower in ability than Class 2 on both the PPVT-III and the…

  13. Report on "A" Testing. Beginning Teacher Evaluation Study. Technical Note Series. Technical Note III-2.

    ERIC Educational Resources Information Center

    Cahen, Leonard S.

    The "A" testing program of the Beginning Teacher Evaluation Study, Phase III-B, is summarized. A sample of 150 second grade and 134 fifth grade students completed the reading and mathematics achievement battery, as well as affective scales regarding reading, mathematics, and school. The administration procedures, test results, and psychometric…

  14. Report of "B" Testing. Beginning Teacher Evaluation Study. Technical Note Series. Technical Note III-3.

    ERIC Educational Resources Information Center

    Cahen, Leonard S.

    The "B" testing program of the Beginning Teacher Evaluation Study, Phase III-B, is summarized. A sample of 146 second grade and 128 fifth grade students completed the reading and mathematics achievement battery, as well as affective scales pertaining to reading, mathematics, and school. The administration procedures, test results, and psychometric…

  15. 21 CFR 866.5440 - Beta-2-glycoprotein III immunological test system.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Beta-2-glycoprotein III immunological test system. 866.5440 Section 866.5440 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES IMMUNOLOGY AND MICROBIOLOGY DEVICES Immunological Test Systems §...

  16. 21 CFR 866.5440 - Beta-2-glycoprotein III immunological test system.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Beta-2-glycoprotein III immunological test system. 866.5440 Section 866.5440 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES IMMUNOLOGY AND MICROBIOLOGY DEVICES Immunological Test Systems §...

  17. III-V nitride semiconductors for solar hydrogen production

    NASA Astrophysics Data System (ADS)

    Parameshwaran, Vijay; Gallinat, Chad; Enck, Ryan W.; Sampath, Anand V.; Shen, Paul H.; Kuykendall, Tevye; Aloni, Shaul; Wraback, Michael; Clemens, Bruce M.

    2012-06-01

    Photoelectrochemical cells are devices that can convert solar radiation to hydrogen gas through a water decomposition process. In this process, energy is converted from incident photons to the bonds of the generated H2 molecules. The solar radiation absorption, electron-hole pair splitting, and photoelectrolysis half reactions all occur in the vicinity of the electrode-electrolyte interface. As a result, engineering the electrode material and its interaction with the electrolyte is important in investigating and improving the energy conversion process in these devices. III-V nitride materials are promising candidates for photoelectrochemical energy applications. We demonstrate solar-to-hydrogen conversion in these cells using p-type GaN and n-type InGaN as a photocathode and photoanode material, respectively. Additionally, we demonstrate heteroepitaxial MOCVD growth of GaP on Si, enabling future work in developing GaPN as a photocathode material.

  18. Could test length or order affect scores on letter number sequencing of the WAIS-III and WMS-III? Ruling out effects of fatigue.

    PubMed

    Tulsky, D S; Zhu, J

    2000-11-01

    The Letter Number Sequencing subtest of the WAIS-III and WMS-III was administered at the end of the standardization edition of the WMS-III. It was not administered as part of the WAIS-III standardization battery. Nevertheless, the subtest was included in the published version of the WAIS-III. This study examines differences between examinees administered the Letter Number Sequencing subtest at three different times during a psychological battery: (1) as part of the published battery, (2) as part of the WMS-III when the WMS-III was administered as the first test in a sequence, and (3) as part of the WMS-III standardization when the WAIS-III was administered immediately preceding the WMS-III. The participants were 372 examinees ( n = 124 in each condition) who were matched on key demographic variables. A repeated measures MANOVA yielded no difference in subtest scores when administered in any of these conditions. The results show no evidence of fatigue or ordering effects on the Letter Number Sequencing subtest.

  19. Permanganate oxidation of arsenic(III): Reaction stoichiometry and the characterization of solid product

    NASA Astrophysics Data System (ADS)

    Lee, Giehyeon; Song, Kyungsun; Bae, Jongseong

    2011-09-01

    Permanganate (MnO 4-) has widely been used as an effective oxidant for drinking water treatment systems, as well as for in situ treatment of groundwater impacted by various organic contaminants. The reaction stoichiometry of As(III) oxidation by permanganate has been assumed to be 1.5, based on the formation of solid product, which is putatively considered to be MnO 2(s). This study determined the stoichiometric ratio (SR) of the oxidation reaction with varying doses of As(III) (3-300 μM) and MnO 4- (0.5 or 300 μM) under circumneutral pH conditions (pH 4.5-7.5). We also characterized the solid product that was recovered ˜1 min after the oxidation of 2.16 mM As(III) by 0.97 mM MnO 4- at pH 6.9 and examined the feasibility of secondary heterogeneous As(III) oxidation by the solid product. When permanganate was in excess of As(III), the SR of As(III) to Mn(VII) was 2.07 ± 0.07, regardless of the solution pH; however, it increased to 2.49 ± 0.09 when As(III) was in excess. The solid product was analogous to vernadite, a poorly crystalline manganese oxide based on XRD analysis. The average valence of structural Mn in the solid product corresponded to +III according to the splitting interval of the Mn3s peaks (5.5 eV), determined using X-ray photoelectron spectroscopy (XPS). The relative proportions of the structural Mn(IV):Mn(III):Mn(II) were quantified as 19:62:19 by fitting the Mn2p 3/2 spectrum of the solid with the five multiplet binding energy spectra for each Mn valence. Additionally, the O1s spectrum of the solid was comparable to that of Mn-oxide but not of Mn-hydroxide. These results suggest that the solid product resembled a poorly crystalline hydrous Mn-oxide such as (Mn II0.19Mn III0.62Mn IV0.19) 2O 3· nH 2O, in which Mn(II) and Mn(IV) were presumably produced from the disproportionation of aqueous phase Mn(III). Thermodynamic calculations also show that the formation of Mn(III) oxide is more favorable than that of Mn(IV) oxide from As(III) oxidation

  20. Suited and Unsuited Hybrid III Impact Testing and Finite Element Model Characterization

    NASA Technical Reports Server (NTRS)

    Lawrence, C.; Somers, J. T.; Baldwin, M. A.; Wells, J. A.; Newby, N.; Currie, N. J.

    2016-01-01

    NASA spacecraft design requirements for occupant protection are a combination of the Brinkley Dynamic Response Criteria and injury assessment reference values (IARV) extracted from anthropomorphic test devices (ATD). For the ATD IARVs, the requirements specify the use of the 5th percentile female Hybrid III and the 95th percentile male Hybrid III. Each of these ATDs is required to be fitted with an articulating pelvis (also known as the aerospace pelvis) and a straight spine. The articulating pelvis is necessary for the ATD to fit into spacecraft seats, while the straight spine is required as injury metrics for vertical accelerations are better defined for this configuration. Sled testing of the Hybrid III 5th Percentile Female Anthropomorphic Test Device (ATD) was performed at Wright-Patterson Air Force Base (WAPFB). Two 5th Percentile ATDs were tested, the Air Force Research Lab (AFRL) and NASA owned Hybrid III ATDs with aerospace pelvises. Testing was also conducted with a NASA-owned 95th Percentile Male Hybrid III with aerospace pelvis at WPAFB. Testing was performed using an Orion seat prototype provided by Johnson Space Center (JSC). A 5-point harness comprised of 2 inch webbing was also provided by JSC. For suited runs, a small and extra-large Advanced Crew Escape System (ACES) suit and helmet were also provided by JSC. Impact vectors were combined frontal/spinal and rear/lateral. Some pure spinal and rear axis testing was also performed for model validation. Peak accelerations ranged between 15 and 20-g. This range was targeted because the ATD responses fell close to the IARV defined in the Human-Systems Integration Requirements (HSIR) document. Rise times varied between 70 and 110 ms to assess differences in ATD responses and model correlation for different impact energies. The purpose of the test series was to evaluate the Hybrid III ATD models in Orion-specific landing orientations both with and without a spacesuit. The results of these tests were used

  1. Validation of the U.S. NRC coupled code system TRITON/TRACE/PARCS with the special power excursion reactor test III (SPERT III)

    SciTech Connect

    Wang, R. C.; Xu, Y.; Downar, T.; Hudson, N.

    2012-07-01

    The Special Power Excursion Reactor Test III (SPERT III) was a series of reactivity insertion experiments conducted in the 1950's. This paper describes the validation of the U.S. NRC Coupled Code system TRITON/PARCS/TRACE to simulate reactivity insertion accidents (RIA) by using several of the SPERT III tests. The work here used the SPERT III E-core configuration tests in which the RIA was initiated by ejecting a control rod. The resulting super-prompt reactivity excursion and negative reactivity feedback produced the familiar bell shaped power increase and decrease. The energy deposition during such a power peak has important safety consequences and provides validation basis for core coupled multi-physics codes. The transients of five separate tests are used to benchmark the PARCS/TRACE coupled code. The models were thoroughly validated using the original experiment documentation. (authors)

  2. Supplement III to Changes in Farm Production and Efficiency.

    ERIC Educational Resources Information Center

    Economic Research Service (USDA), Washington, DC.

    This publication contains data on man-hours of labor used for farmwork in the farm production regions of the Northeast, Lake States, Corn Belt, Northern Plains, Appalachia, Southeast, Delta States, Southern Plains, Mountain, and Pacific. Regional data from 1950-1958 are provided in table form for the livestock enterprises of meat animals, milk…

  3. 16 CFR 1204.16 - Production testing.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 16 Commercial Practices 2 2014-01-01 2014-01-01 false Production testing. 1204.16 Section 1204.16 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION CONSUMER PRODUCT SAFETY ACT REGULATIONS SAFETY STANDARD FOR OMNIDIRECTIONAL CITIZENS BAND BASE STATION ANTENNAS Certification § 1204.16 Production...

  4. 16 CFR 1204.16 - Production testing.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 16 Commercial Practices 2 2012-01-01 2012-01-01 false Production testing. 1204.16 Section 1204.16 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION CONSUMER PRODUCT SAFETY ACT REGULATIONS SAFETY STANDARD FOR OMNIDIRECTIONAL CITIZENS BAND BASE STATION ANTENNAS Certification § 1204.16 Production...

  5. 16 CFR 1204.16 - Production testing.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 16 Commercial Practices 2 2013-01-01 2013-01-01 false Production testing. 1204.16 Section 1204.16 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION CONSUMER PRODUCT SAFETY ACT REGULATIONS SAFETY STANDARD FOR OMNIDIRECTIONAL CITIZENS BAND BASE STATION ANTENNAS Certification § 1204.16 Production...

  6. 16 CFR 1204.16 - Production testing.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... production interval will meet the standard, production must cease and the faulty manufacturing process or... 16 Commercial Practices 2 2011-01-01 2011-01-01 false Production testing. 1204.16 Section 1204.16... STANDARD FOR OMNIDIRECTIONAL CITIZENS BAND BASE STATION ANTENNAS Certification § 1204.16 Production...

  7. Test Marketing in New Product Development

    ERIC Educational Resources Information Center

    Klompmaker, Jay E.; And Others

    1976-01-01

    Discusses the role of test marketing in new product development, based on interviews with marketing executives. Attempts to clarify when a test market should be done, what its aims should be, and how it should be used. (JG)

  8. Concordance between the CVLT and the WMS-III word lists test.

    PubMed

    McDowell, Bradley D; Bayless, John D; Moser, David J; Meyers, John E; Paulsen, Jane S

    2004-03-01

    The California Verbal Learning Test (CVLT) and the Word Lists Test (WLT) from the Wechsler Memory Scale-III are widely used tests of verbal learning and memory. To examine concordance between these popular tests, we administered both to a diagnostically diverse group of 25 patients. As expected, measures from the two tests were highly correlated, although level of concordance was not as high as might be expected. When diagnostic outcomes were discordant for free recall measures, the CVLT indicated impairment more often than did the WLT.

  9. Relation between Kaufman Brief Intelligence Test and WISC-III Scores of Children with RD.

    ERIC Educational Resources Information Center

    Chin, Christopher E.; Ledesma, Heloise Marie L.; Cirino, Paul T.; Sevcik, Rose A.; Morris, Robin D.; Frijters, Jan C.; Lovett, Maureen W.

    2001-01-01

    Concurrent validity of the Kaufman Brief Intelligence Test (K-BIT) with the Wechsler Intelligence Scale for Children-Third Edition (WISC-III) was evaluated. Both measures were administered to 65 children (ages 6-7). Results suggest caution against using the K-BIT exclusively for placement and diagnostic purposes with young children with reading…

  10. 30 CFR 57.22229 - Weekly testing (I-A, III, and V-A mines).

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Weekly testing (I-A, III, and V-A mines). 57.22229 Section 57.22229 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-UNDERGROUND METAL AND NONMETAL MINES Safety Standards for Methane in Metal...

  11. 30 CFR 57.22229 - Weekly testing (I-A, III, and V-A mines).

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Weekly testing (I-A, III, and V-A mines). 57.22229 Section 57.22229 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-UNDERGROUND METAL AND NONMETAL MINES Safety Standards for Methane in Metal...

  12. Walking Versus Jogging in Stages III and IV of the Bruce Treadmill Test.

    ERIC Educational Resources Information Center

    Cundiff, D.; Schwane, J.

    Observations during research involving the Bruce Treadmill Test (BTMT) indicating that Stage III for females and Stage IV for males represented speeds which are intermediate between comfortable walking and confortable jogging for many subjects, prompted this study to determine ways to obtain more consistent group results. Twenty-eight subjects…

  13. Structure and Mechanistic Implications of a Uroporphyrinogen III Synthase−Product Complex

    SciTech Connect

    Schubert,H.; Phillips, J.; Heroux, A.; Hill, C.

    2008-01-01

    Uroporphyrinogen III synthase (U3S) catalyzes the asymmetrical cyclization of a linear tetrapyrrole to form the physiologically relevant uroporphyrinogen III (uro'gen III) isomer during heme biosynthesis. Here, we report four apoenzyme and one product complex crystal structures of the Thermus thermophilus (HB27) U3S protein. The overlay of eight crystallographically unique U3S molecules reveals a huge range of conformational flexibility, including a 'closed' product complex. The product, uro'gen III, binds between the two domains and is held in place by a network of hydrogen bonds between the product's side chain carboxylates and the protein's main chain amides. Interactions of the product A and B ring carboxylate side chains with both structural domains of U3S appear to dictate the relative orientation of the domains in the closed enzyme conformation and likely remain intact during catalysis. The product C and D rings are less constrained in the structure, consistent with the conformational changes required for the catalytic cyclization with inversion of D ring orientation. A conserved tyrosine residue is potentially positioned to facilitate loss of a hydroxyl from the substrate to initiate the catalytic reaction.

  14. [Governmental batch sample testing of allergen products].

    PubMed

    Bartel, D; Führer, F; Vieths, S

    2012-03-01

    Allergen products for specific immunotherapy of type I allergies were first authorized for the German market in the 1970s. In addition to finished products manufactured in advance and in batches, so-called named patient products have recently been defined as Medicinal Products by the German Medicinal Products Act ("Arzneimittelgesetz", AMG 14th Revision 2005). Some allergen products previously marketed as named patient products are now required to obtain marketing authorization according to the German ordinance for therapy allergens. Products have to be batch released by the competent German Federal Agency, the Paul-Ehrlich-Institut (PEI). Samples of product batches are delivered to the PEI in order to perform experimental quality controls. With regard to named patient products, PEI tests batch samples of the bulk extract preparations used for manufacturing of the respective, named patient products. The institute releases approximately 2,800 allergen product batches annually.

  15. Operations manual for the data acquisition and reduction system, Area III Actuator Test Facility

    SciTech Connect

    Smith, E.L.

    1984-03-01

    This manual describes the operation of the new minicomputer-based data acquisition and reduction system for the Area III Actuator Test Facility at Sandia National Laboratories. The stand-alone digital system will alleviate current problems with test control and analysis and with data presentation. In its initial configuration, it will digitize test results recorded on FM tape and present the data graphically for reports. The ultimate goal of this system is to upgrade the performance, safety, and turnaround time of actuator tests through improved quality, analysis, and presentation of data.

  16. 40 CFR Table 3 to Subpart III of... - Compliance Requirements for Slabstock Foam Production Affected Sources Complying With the...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Foam Production Affected Sources Complying With the Emission Point Specific Limitations 3 Table 3 to... Standards for Hazardous Air Pollutants for Flexible Polyurethane Foam Production Pt. 63, Subpt. III, Table 3 Table 3 to Subpart III of Part 63—Compliance Requirements for Slabstock Foam Production Affected...

  17. 40 CFR Table 3 to Subpart III of... - Compliance Requirements for Slabstock Foam Production Affected Sources Complying With the...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Foam Production Affected Sources Complying With the Emission Point Specific Limitations 3 Table 3 to... Standards for Hazardous Air Pollutants for Flexible Polyurethane Foam Production Pt. 63, Subpt. III, Table 3 Table 3 to Subpart III of Part 63—Compliance Requirements for Slabstock Foam Production Affected...

  18. 40 CFR Table 4 to Subpart III of... - Compliance Requirements for Slabstock Foam Production Affected Sources Complying With the Source...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Foam Production Affected Sources Complying With the Source-Wide Emission Limitation 4 Table 4 to... Standards for Hazardous Air Pollutants for Flexible Polyurethane Foam Production Pt. 63, Subpt. III, Table 4 Table 4 to Subpart III of Part 63—Compliance Requirements for Slabstock Foam Production Affected...

  19. 40 CFR Table 4 to Subpart III of... - Compliance Requirements for Slabstock Foam Production Affected Sources Complying With the Source...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Foam Production Affected Sources Complying With the Source-Wide Emission Limitation 4 Table 4 to... Standards for Hazardous Air Pollutants for Flexible Polyurethane Foam Production Pt. 63, Subpt. III, Table 4 Table 4 to Subpart III of Part 63—Compliance Requirements for Slabstock Foam Production Affected...

  20. 40 CFR Table 3 to Subpart III of... - Compliance Requirements for Slabstock Foam Production Affected Sources Complying With the...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Foam Production Affected Sources Complying With the Emission Point Specific Limitations 3 Table 3 to... Standards for Hazardous Air Pollutants for Flexible Polyurethane Foam Production Pt. 63, Subpt. III, Table 3 Table 3 to Subpart III of Part 63—Compliance Requirements for Slabstock Foam Production Affected...

  1. Arsenic(III) and arsenic(V) reactions with zerovalent iron corrosion products.

    PubMed

    Manning, Bruce A; Hunt, Mathew L; Amrhein, Christopher; Yarmoff, Jory A

    2002-12-15

    Zerovalent iron (Fe0) has tremendous potential as a remediation material for removal of arsenic from groundwater and drinking water. This study investigates the speciation of arsenate (As(V)) and arsenite (As(III)) after reaction with two Fe0 materials, their iron oxide corrosion products, and several model iron oxides. A variety of analytical techniques were used to study the reaction products including HPLC-hydride generation atomic absorption spectrometry, X-ray diffraction, scanning electron microscopy-energy-dispersive X-ray analysis, and X-ray absorption spectroscopy. The products of corrosion of Fe0 include lepidocrocite (gamma-FeOOH), magnetite (Fe3O4), and/or maghemite (gamma-Fe2O3), all of which indicate Fe(II) oxidation as an intermediate step in the Fe0 corrosion process. The in-situ Fe0 corrosion reaction caused a high As(III) and As(V) uptake with both Fe0 materials studied. Under aerobic conditions, the Fe0 corrosion reaction did not cause As(V) reduction to As(III) but did cause As(III) oxidation to As(V). Oxidation of As(III) was also caused by maghemite and hematite minerals indicating that the formation of certain iron oxides during Fe0 corrosion favors the As(V) species. Water reduction and the release of OH- to solution on the surface of corroding Fe0 may also promote As(III) oxidation. Analysis of As(III) and As(V) adsorption complexes in the Fe0 corrosion products and synthetic iron oxides by extended X-ray absorption fine structure spectroscopy (EXAFS) gave predominant As-Fe interatomic distances of 3.30-3.36 A. This was attributed to inner-sphere, bidentate As(III) and As(V) complexes. The results of this study suggest that Fe0 can be used as a versatile and economical sorbent for in-situ treatment of groundwater containing As(III) and As(V).

  2. 48 CFR 52.234-1 - Industrial Resources Developed Under Defense Production Act Title III.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 2 2011-10-01 2011-10-01 false Industrial Resources... CLAUSES Text of Provisions and Clauses 52.234-1 Industrial Resources Developed Under Defense Production Act Title III. As prescribed at 34.104, insert the following clause: Industrial Resources...

  3. 48 CFR 52.234-1 - Industrial Resources Developed Under Defense Production Act Title III.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 2 2013-10-01 2013-10-01 false Industrial Resources... CLAUSES Text of Provisions and Clauses 52.234-1 Industrial Resources Developed Under Defense Production Act Title III. As prescribed at 34.104, insert the following clause: Industrial Resources...

  4. 48 CFR 52.234-1 - Industrial Resources Developed Under Defense Production Act Title III.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false Industrial Resources... CLAUSES Text of Provisions and Clauses 52.234-1 Industrial Resources Developed Under Defense Production Act Title III. As prescribed at 34.104, insert the following clause: Industrial Resources...

  5. 48 CFR 52.234-1 - Industrial Resources Developed Under Defense Production Act Title III.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 2 2012-10-01 2012-10-01 false Industrial Resources... CLAUSES Text of Provisions and Clauses 52.234-1 Industrial Resources Developed Under Defense Production Act Title III. As prescribed at 34.104, insert the following clause: Industrial Resources...

  6. 48 CFR 52.234-1 - Industrial Resources Developed Under Defense Production Act Title III.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 2 2014-10-01 2014-10-01 false Industrial Resources... CLAUSES Text of Provisions and Clauses 52.234-1 Industrial Resources Developed Under Defense Production Act Title III. As prescribed at 34.104, insert the following clause: Industrial Resources...

  7. 75 FR 67054 - Listing of Approved Drug Products Containing Dronabinol in Schedule III

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-01

    ...\\ 51 FR 17476 (May 13, 1986). DEA subsequently transferred the FDA-approved Marinol formulation from schedule II to schedule III. 64 FR 35928 (July 2, 1999). Recently, firms have submitted to FDA ANDAs for... product is a generic formulation of Marinol and contains dronabinol, the (-) isomer of delta-9-...

  8. Flare fragmentation and type III productivity in the 1980 June 27 flare

    NASA Technical Reports Server (NTRS)

    Aschwanden, M. J.; Schwartz, R. A.; Benz, A. O.; Lin, R. P.; Pelling, R. M.

    1990-01-01

    Observations of the solar flare on June 27, 1980 were presented, 16:14-16:33 UT, which was observed by a balloon-borne 300 sq cm phoswich hard X-ray detector and by the IKARUS radio spectrometer. This flare shows intense hard X-ray (HXR) emission and an extreme productivity of (at least 754) type III bursts at 200-400 MHz. A linear correlation was found between the type III burst rate and the HXR fluence. The occurrence of about 10 type III bursts/second, and also the even higher rate of millisecond spikes, suggests a high degree of fragmentation in the acceleration region. This high quantization of injected beams, assuming the thick-target model, shows up in a linear relationship between hard X-ray fluence and the type III rate, but not as fine structures in the HXR time profile. The generation of a superhot isothermal HXR component in the decay phase of the flare coincides with the fade-out of type III production.

  9. Significance of iron(II,III) hydroxycarbonate green rust in arsenic remediation using zerovalent iron in laboratory column tests.

    PubMed

    Su, Chunming; Puls, Robert W

    2004-10-01

    We examined the corrosion products of zerovalent iron used in three column tests for removing arsenic from water under dynamic flow conditions. Each column test lasted 3-4 months using columns consisting of a 10.3-cm depth of 50:50 (w:w, Peerless iron:sand) in the middle and a 10.3cm depth of a sediment from Elizabeth City, NC, in both upper and lower portions of the 31-cm-long glass column (2.5 cm in diameter). The feeding solutions were 1 mg of As(V) L(-1) + 1 mg of As(III) L(-1) in 7 mM NaCl + 0.86 mM CaSO4 with or without added phosphate (0.5 or 1 mg of P L(-1)) and silicate (10 or 20 mg of Si L(-1)) at pH 6.5. Iron(II,III) hydroxycarbonate green rust (or simply, carbonate green rust) and magnetite were the major iron corrosion products identified with X-ray diffraction for the separated fractions (5 and 1 min sedimentation and residual). The presence of carbonate green rust was confirmed by scanning electron microscopy (hexagonal morphology) and FTIR-photoacoustic spectroscopy (interlayer carbonate stretching mode at 1352-1365 cm(-1)). X-ray photoelectron spectroscopy investigation revealed the presence of predominantly As(V) at the surface of corroded iron particles despite the fact that the feeding solution in contact with Peerless iron contained more As(III) than As(V) as a result of a preferential uptake of As(V) over As(III) by the Elizabeth City sediment. Extraction of separated corrosion products with 1.0 M HCI showed that from 86 to 96% of the total extractable As (6.9-14.6 g kg(-1)) was in the form of As(V) in agreement with the XPS results. Combined microscopic and macroscopic wet chemistry results suggest that sorbed As(III) was partially oxidized by the carbonate green rust at the early stage of iron corrosion. The column experiments suggest that either carbonate green rust is kinetically favored or is thermodynamically more stable than sulfate green rust in the studied Peerless iron corrosion systems.

  10. Measuring test productivity - The elusive dream

    NASA Astrophysics Data System (ADS)

    Ward, D. T.; Cross, E. J., Jr.

    1983-11-01

    The paper summarizes definitions and terminology relating to measurement of Test and Evaluation productivity before settling on the appropriate criteria for such a measurement model. A productivity measurement scheme suited for use by Test and Evaluation organizations is suggested. This mathematical model is a simplified version of one proposed by the American Productivity Center and applied to an aircraft maintenance facility by Fletcher. It includes only four primary variables: safety, schedule, cost, and deficiencies reported with varying degrees of objectivity and subjectivity involved in quantifying them. A hypothetical example of a fighter aircraft flight test program is used to illustrate the application of the productivity measurement model. The proposed model is intended to serve as a first iteration procedure and should be tested against real test programs to verify and refine it.

  11. Novel findings in patients with primary hyperoxaluria type III and implications for advanced molecular testing strategies.

    PubMed

    Beck, Bodo B; Baasner, Anne; Buescher, Anja; Habbig, Sandra; Reintjes, Nadine; Kemper, Markus J; Sikora, Przemyslaw; Mache, Christoph; Pohl, Martin; Stahl, Mirjam; Toenshoff, Burkhard; Pape, Lars; Fehrenbach, Henry; Jacob, Dorrit E; Grohe, Bernd; Wolf, Matthias T; Nürnberg, Gudrun; Yigit, Gökhan; Salido, Eduardo C; Hoppe, Bernd

    2013-02-01

    Identification of mutations in the HOGA1 gene as the cause of autosomal recessive primary hyperoxaluria (PH) type III has revitalized research in the field of PH and related stone disease. In contrast to the well-characterized entities of PH type I and type II, the pathophysiology and prevalence of type III is largely unknown. In this study, we analyzed a large cohort of subjects previously tested negative for type I/II by complete HOGA1 sequencing. Seven distinct mutations, among them four novel, were found in 15 patients. In patients of non-consanguineous European descent the previously reported c.700+5G>T splice-site mutation was predominant and represents a potential founder mutation, while in consanguineous families private homozygous mutations were identified throughout the gene. Furthermore, we identified a family where a homozygous mutation in HOGA1 (p.P190L) segregated in two siblings with an additional AGXT mutation (p.D201E). The two girls exhibiting triallelic inheritance presented a more severe phenotype than their only mildly affected p.P190L homozygous father. In silico analysis of five mutations reveals that HOGA1 deficiency is causing type III, yet reduced HOGA1 expression or aberrant subcellular protein targeting is unlikely to be the responsible pathomechanism. Our results strongly suggest HOGA1 as a major cause of PH, indicate a greater genetic heterogeneity of hyperoxaluria, and point to a favorable outcome of type III in the context of PH despite incomplete or absent biochemical remission. Multiallelic inheritance could have implications for genetic testing strategies and might represent an unrecognized mechanism for phenotype variability in PH.

  12. The catalytic efficiency of yeast ribonuclease III depends on substrate specific product release rate

    PubMed Central

    Comeau, Marc-Andre; Lafontaine, Daniel A.; Abou Elela, Sherif

    2016-01-01

    Members of the ribonuclease III (RNase III) family regulate gene expression by triggering the degradation of double stranded RNA (dsRNA). Hundreds of RNase III cleavage targets have been identified and their impact on RNA maturation and stability is now established. However, the mechanism defining substrates’ reactivity remains unclear. In this study, we developed a real-time FRET assay for the detection of dsRNA degradation by yeast RNase III (Rnt1p) and characterized the kinetic bottlenecks controlling the reactivity of different substrates. Surprisingly, the results indicate that Rnt1p cleavage reaction is not only limited by the rate of catalysis but can also depend on base-pairing of product termini. Cleavage products terminating with paired nucleotides, like the degradation signals found in coding mRNA sequence, were less reactive and more prone to inhibition than products having unpaired nucleotides found in non-coding RNA substrates. Mutational analysis of U5 snRNA and Mig2 mRNA confirms the pairing of the cleavage site as a major determinant for the difference between cleavage rates of coding and non-coding RNA. Together the data indicate that the base-pairing of Rnt1p substrates encodes reactivity determinants that permit both constitutive processing of non-coding RNA while limiting the rate of mRNA degradation. PMID:27257067

  13. ConocoPhillips Gas Hydrate Production Test

    SciTech Connect

    Schoderbek, David; Farrell, Helen; Howard, James; Raterman, Kevin; Silpngarmlert, Suntichai; Martin, Kenneth; Smith, Bruce; Klein, Perry

    2013-06-30

    Work began on the ConocoPhillips Gas Hydrates Production Test (DOE award number DE-NT0006553) on October 1, 2008. This final report summarizes the entire project from January 1, 2011 to June 30, 2013.

  14. Presentation order effects in product taste tests.

    PubMed

    Dean, M L

    1980-05-01

    Presentation order in paired-comparison testing was varied to measure the impact of primacy versus recency effects on consumer product evaluations. Overall preference and product rating scores were gathered for 1196 male and female Ss aged 13--49 years in two consumer research studies covering 11 taste tests. First position preference bias characterized the findings, lending support to the attention decrement hypothesis or a suggested palate desensitization effect on subsequent taste trial behavior.

  15. 40 CFR Table 3 to Subpart III of... - Compliance Requirements for Slabstock Foam Production Affected Sources Complying With the...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Foam Production Affected Sources Complying With the Emission Point Specific Limitations 3 Table 3 to...) National Emission Standards for Hazardous Air Pollutants for Flexible Polyurethane Foam Production Pt. 63, Subpt. III, Table 3 Table 3 to Subpart III of Part 63—Compliance Requirements for Slabstock...

  16. 40 CFR Table 3 to Subpart III of... - Compliance Requirements for Slabstock Foam Production Affected Sources Complying With the...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Foam Production Affected Sources Complying With the Emission Point Specific Limitations 3 Table 3 to...) National Emission Standards for Hazardous Air Pollutants for Flexible Polyurethane Foam Production Pt. 63, Subpt. III, Table 3 Table 3 to Subpart III of Part 63—Compliance Requirements for Slabstock...

  17. 40 CFR Table 4 to Subpart III of... - Compliance Requirements for Slabstock Foam Production Affected Sources Complying With the Source...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Foam Production Affected Sources Complying With the Source-Wide Emission Limitation 4 Table 4 to...) National Emission Standards for Hazardous Air Pollutants for Flexible Polyurethane Foam Production Pt. 63, Subpt. III, Table 4 Table 4 to Subpart III of Part 63—Compliance Requirements for Slabstock...

  18. 40 CFR Table 4 to Subpart III of... - Compliance Requirements for Slabstock Foam Production Affected Sources Complying With the Source...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Foam Production Affected Sources Complying With the Source-Wide Emission Limitation 4 Table 4 to...) National Emission Standards for Hazardous Air Pollutants for Flexible Polyurethane Foam Production Pt. 63, Subpt. III, Table 4 Table 4 to Subpart III of Part 63—Compliance Requirements for Slabstock...

  19. 16 CFR 1209.36 - Production testing.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... SAFETY STANDARD FOR CELLULOSE INSULATION Certification § 1209.36 Production testing. (a) General. Manufacturers, private labelers, and importers shall test the cellulose insulation periodically as it is... standard or a portion of the standard, the insulation produced during the interval will also meet...

  20. 16 CFR 1209.36 - Production testing.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... SAFETY STANDARD FOR CELLULOSE INSULATION Certification § 1209.36 Production testing. (a) General. Manufacturers, private labelers, and importers shall test the cellulose insulation periodically as it is... standard or a portion of the standard, the insulation produced during the interval will also meet...

  1. 16 CFR 1209.36 - Production testing.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... SAFETY STANDARD FOR CELLULOSE INSULATION Certification § 1209.36 Production testing. (a) General. Manufacturers, private labelers, and importers shall test the cellulose insulation periodically as it is... standard or a portion of the standard, the insulation produced during the interval will also meet...

  2. 16 CFR 1209.36 - Production testing.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... SAFETY STANDARD FOR CELLULOSE INSULATION Certification § 1209.36 Production testing. (a) General. Manufacturers, private labelers, and importers shall test the cellulose insulation periodically as it is... standard or a portion of the standard, the insulation produced during the interval will also meet...

  3. 16 CFR 1209.36 - Production testing.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... SAFETY STANDARD FOR CELLULOSE INSULATION Certification § 1209.36 Production testing. (a) General. Manufacturers, private labelers, and importers shall test the cellulose insulation periodically as it is... can be corrected (see § 1209.37) so as to yield passing results and meet the standard....

  4. Hybrid III anthropomorphic test device (ATD) response to head impacts and potential implications for athletic headgear testing.

    PubMed

    Bartsch, Adam; Benzel, Edward; Miele, Vincent; Morr, Douglas; Prakash, Vikas

    2012-09-01

    The Hybrid III 50th percentile male anthropomorphic test device (ATD) is the most widely used human impact testing surrogate and has historically been used in automotive or military testing. More recently, this ATD is finding use in applications evaluating athletic helmet protectivity, quantifying head impact dosage and estimating injury risk. But ATD head-neck response has not been quantified in omnidirectional athletic-type head impacts absent axial preload. It is probable that headgear injury reduction that can be quantified in a laboratory, including in American football, boxing, hockey, lacrosse and soccer, is related to a number of interrelated kinetic and kinematic factors, such as head center of gravity linear acceleration, head angular acceleration, head angular velocity, occipito-cervical mechanics and neck stiffness. Therefore, we characterized ATD head-neck dynamic response to direct head impacts in a series of front, oblique front and lateral head impacts. Key findings were: (1) impacts producing highest ATD resultant center of gravity linear acceleration resulted in the lowest resultant occipito-cervical spine bending moment/force. (2) Resultant ATD head angular velocity and angular acceleration did not appear coupled to impact direction at lower impact energy levels; these parameters were coupled at higher energy levels. (3) The ATD had progressively increasing occipito-cervical stiffness in extension, torsion and lateral bending, respectively. Because the ATD neck influenced head and neck impact dosage parameters, testing agencies, manufacturers and researchers should consider using the Hybrid III head form attached to a neck as a means to quantify head and neck injury risks as opposed to systems that do not utilize a neck. This heightened understanding of Hybrid III ATD head-neck response, and consideration of order of stiffest axes in the lateral, oblique and extension directions, respectively, should aid in the development of head and neck injury

  5. Genotoxicity testing of Maillard reaction products.

    PubMed

    Shibamoto, T

    1989-01-01

    Since the development of short-term genotoxicity tests such as the Ames assay, the mutagenicity of Maillard reaction products has been tested extensively. Some products have exhibited strong activity. For example, one of the earliest studies demonstrated some mutagenic activity in a dichloromethane extract of a D-glucose/ammonia Maillard model system. Many researchers have attempted to pinpoint the principal chemical(s) of mutagenicity of the Maillard products using various sugar-amino acid browning model systems over last two decades. However, no mutagenic individual Maillard product has been isolated and identified. Nitrite has been also used as a reactant in browning reaction model systems, primarily to investigate the formation of potentially mutagenic or carcinogenic N-nitroso compounds. Recently some potent mutagens isolated from pyrolyzed amino acids or proteins have begun to receive attention as Maillard reaction products. PMID:2675034

  6. PREFACE: III All-Russian Scientific and Practical Conference on Innovations in Non-Destructive Testing (SibTest 2015)

    NASA Astrophysics Data System (ADS)

    2016-01-01

    This issue of the journal is devoted to the research and studies presented at the III All-Russian Scientific and Practical Conference on Innovations in Non-Destructive Testing SibTest. The conference was held in Altai, Russia, on 27-31 July 2015. The conference brought together experts from different countries and organizations who had a great opportunity to share knowledge during oral and poster presentations and to initiate discussions on topics that are of interest to the conference attendees. The conference aimed to discuss innovative methods and the application of advanced technologies in non-destructive testing. The conference also attempted to bring together university, academic and industrial science, to expand the co-operation of scientists from different countries in research and development and the commercialization of innovative technologies in non-destructive testing. The key themes of the conference were: ultrasonic and acoustic testing; electromagnetic and thermal testing; various types of radiation non-destructive testing; passive and active testing techniques. The conference organizers are the Institute of Non-Destructive Testing, Tomsk Polytechnic University, with the assistance of the Russian Society for Non-Destructive Testing and Technical Diagnostics, Institute of Strength Physics and Materials Science, Siberian Branch of the Russian Academy of Sciences, National Research Tomsk State University, Moscow State Institute of Radio Engineering, Electronics and Automation.

  7. The Effect of Grade Norms in College Students: Using the Woodcock-Johnson III Tests of Achievement

    ERIC Educational Resources Information Center

    Cressman, Markus N.; Liljequist, Laura

    2014-01-01

    The "Woodcock-Johnson III" Tests of Achievement grade norms versus age norms were examined in the calculation of discrepancy scores in 202 college students. Difference scores were calculated between the "Wechsler Adult Intelligence Scale-3rd Edition" Full Scale IQ and the "Woodcock-Johnson III" Total Achievement,…

  8. Football helmet drop tests on different fields using an instrumented Hybrid III head.

    PubMed

    Viano, David C; Withnall, Chris; Wonnacott, Michael

    2012-01-01

    An instrumented Hybrid III head was placed in a Schutt ION 4D football helmet and dropped on different turfs to study field types and temperature on head responses. The head was dropped 0.91 and 1.83 m giving impacts of 4.2 and 6.0 m/s on nine different football fields (natural, Astroplay, Fieldturf, or Gameday turfs) at turf temperatures of -2.7 to 23.9 °C. Six repeat tests were conducted for each surface at 0.3 m (1') intervals. The Hybrid III was instrumented with triaxial accelerometers to determine head responses for the different playing surfaces. For the 0.91-m drops, peak head acceleration varied from 63.3 to 117.1 g and HIC(15) from 195 to 478 with the different playing surfaces. The lowest response was with Astroplay, followed by the engineered natural turf. Gameday and Fieldturf involved higher responses. The differences between surfaces decreased in the 1.83 m tests. The cold weather testing involved higher accelerations, HIC(15) and delta V for each surface. The helmet drop test used in this study provides a simple and convenient means of evaluating the compliance and energy absorption of football playing surfaces. The type and temperature of the playing surface influence head responses.

  9. LOWER EXTREMITY FUNCTIONAL TESTS AND RISK OF INJURY IN DIVISION III COLLEGIATE ATHLETES

    PubMed Central

    Heiderscheit, Bryan C.; Manske, Robert C.; Niemuth, Paul E.; Rauh, Mitchell J.

    2013-01-01

    Purpose/Background: Functional tests have been used primarily to assess an athlete's fitness or readiness to return to sport. The purpose of this prospective cohort study was to determine the ability of the standing long jump (SLJ) test, the single‐leg hop (SLH) for distance test, and the lower extremity functional test (LEFT) as preseason screening tools to identify collegiate athletes who may be at increased risk for a time‐loss sports‐related low back or lower extremity injury. Methods: A total of 193 Division III athletes from 15 university teams (110 females, age 19.1 ± 1.1 y; 83 males, age 19.5 ± 1.3 y) were tested prior to their sports seasons. Athletes performed the functional tests in the following sequence: SLJ, SLH, LEFT. The athletes were then prospectively followed during their sports season for occurrence of low back or LE injury. Results: Female athletes who completed the LEFT in $118 s were 6 times more likely (OR=6.4, 95% CI: 1.3, 31.7) to sustain a thigh or knee injury. Male athletes who completed the LEFT in #100 s were more likely to experience a time‐loss injury to the low back or LE (OR=3.2, 95% CI: 1.1, 9.5) or a foot or ankle injury (OR=6.7, 95% CI: 1.5, 29.7) than male athletes who completed the LEFT in 101 s or more. Female athletes with a greater than 10% side‐to‐side asymmetry between SLH distances had a 4‐fold increase in foot or ankle injury (cut point: >10%; OR=4.4, 95% CI: 1.2, 15.4). Male athletes with SLH distances (either leg) at least 75% of their height had at least a 3‐fold increase (OR=3.6, 95% CI: 1.2, 11.2 for the right LE; OR=3.6, 95% CI: 1.2, 11.2 for left LE) in low back or LE injury. Conclusions: The LEFT and the SLH tests appear useful in identifying Division III athletes at risk for a low back or lower extremity sports injury. Thus, these tests warrant further consideration as preparticipatory screening examination tools for sport injury in this population. Clinical Relevance: The single‐leg hop for

  10. Robust electrochemical analysis of As(III) integrating with interference tests: a case study in groundwater.

    PubMed

    Liu, Zhong-Gang; Chen, Xing; Liu, Jin-Huai; Huang, Xing-Jiu

    2014-08-15

    In Togtoh region of Inner Mongolia, northern China, groundwater encountered high concentrations As contamination (greater than 50 μg L(-1)) causes an increasing concern. This work demonstrates an electrochemical protocol for robust (efficient and accurate) determination of As(III) in Togtoh water samples using Au microwire electrode without the need of pretreatment or clean-up steps. Considering the complicated conditions of Togtoh water, the efficiency of Au microwire electrode was systematically evaluated by a series of interference tests, stability and reproducibility measurements. No obvious interference on the determination of As(III) was observed. Especially, the influence of humic acid (HA) was intensively investigated. Electrode stability was also observed with long-term measurements (70 days) in Togtoh water solution and under different temperatures (0-35 °C). Excellent reproducibility (RSD:1.28%) was observed from different batches of Au microwire electrodes. The results obtained at Au microwire electrode were comparable to that obtained by inductively coupled plasma atomic emission spectroscopy (ICP-AES), indicating a good accuracy. These evaluations (efficiency, robustness, and accuracy) demonstrated that the Au microwire electrode was able to determine As(III) in application to real environmental samples.

  11. Improving Quality of Seal Leak Test Product using Six Sigma

    NASA Astrophysics Data System (ADS)

    Luthfi Malik, Abdullah; Akbar, Muhammad; Irianto, Dradjad

    2016-02-01

    Seal leak test part is a polyurethane material-based product. Based on past data, defect level of this product was 8%, higher than the target of 5%. Quality improvement effort was done using six sigma method that included phases of define, measure, analyse, improve, and control. In the design phase, a Delphi method was used to identify factors that were critical to quality. In the measure phase, stability and process capability was measured. Fault tree analysis (FTA) and failure mode and effect analysis (FMEA) were used in the next phase to analize the root cause and to determine the priority issues. Improve phase was done by compiling, selecting, and designing alternative repair. Some improvement efforts were identified, i.e. (i) making a checklist for maintenance schedules, (ii) making written reminder form, (iii) modifying the SOP more detail, and (iv) performing a major service to the vacuum machine. To ensure the continuity of improvement efforts, some control activities were executed, i.e. (i) controlling, monitoring, documenting, and setting target frequently, (ii) implementing reward and punishment system, (iii) adding cleaning tool, and (iv) building six sigma organizational structure.

  12. CLIC RF High Power Production Testing Program

    SciTech Connect

    Syratchev, I.; Riddone, G.; Tantawi, S.G.; /SLAC

    2011-11-02

    The CLIC Power Extraction and Transfer Structure (PETS) is a passive microwave device in which bunches of the drive beam interact with the impedance of the periodically loaded waveguide and generate RF power for the main linac accelerating structure. The demands on the high power production ({approx} 150 MW) and the needs to transport the 100 A drive beam for about 1 km without losses, makes the PETS design rather unique and the operation very challenging. In the coming year, an intense PETS testing program will be implemented. The target is to demonstrate the full performance of the PETS operation. The testing program overview and test results available to date are presented.

  13. Presentation Order Effects in Product Taste Tests.

    ERIC Educational Resources Information Center

    Dean, Michael L.

    1980-01-01

    Presentation order in paired-comparison testing was varied to measure the impact of primacy v recency effects on consumer product evaluation. First position preference bias characterized the findings, lending support to the attention decrement hypothesis or a suggested palate desensitization effect on subsequent taste trial behavior. (Author)

  14. Robotic mannequin technology for enhanced product testing

    SciTech Connect

    Fecht, B.A.; Bennett, D.W.

    1991-06-01

    Engineers at Pacific Northwest Laboratory (PNL) have developed several articulated robotic mannequin systems which closely simulate human anthropometric shape, complex motion and physiological function. These systems provide highly reproducible and realistic tests which aid in the evaluation of high performance clothing, consumer products, and human comfort.

  15. 46 CFR 160.021-4 - Approval and production tests.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 6 2013-10-01 2013-10-01 false Approval and production tests. 160.021-4 Section 160.021... Approval and production tests. (a) Approval tests. The manufacturer must produce a lot of at least 100... Chapter. (b) Production inspections and tests. Production inspections and tests of each lot of...

  16. 21 CFR 866.5440 - Beta-2-glycoprotein III immunological test system.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... the beta-2-glycoprotein III (a serum protein) in serum and other body fluids. Measurement of beta-2-glycoprotein III aids in the diagnosis of an inherited deficiency of this serum protein and a variety of...

  17. Mumps Virus Induces Protein-Kinase-R-Dependent Stress Granules, Partly Suppressing Type III Interferon Production

    PubMed Central

    Hashimoto, Shin; Yamamoto, Soh; Ogasawara, Noriko; Sato, Toyotaka; Yamamoto, Keisuke; Katoh, Hiroshi; Kubota, Toru; Shiraishi, Tsukasa; Kojima, Takashi; Himi, Tetsuo; Tsutsumi, Hiroyuki; Yokota, Shin-ichi

    2016-01-01

    Stress granules (SGs) are cytoplasmic granular aggregations that are induced by cellular stress, including viral infection. SGs have opposing antiviral and proviral roles, which depend on virus species. The exact function of SGs during viral infection is not fully understood. Here, we showed that mumps virus (MuV) induced SGs depending on activation of protein kinase R (PKR). MuV infection strongly induced interferon (IFN)-λ1, 2 and 3, and IFN-β through activation of IFN regulatory factor 3 (IRF3) via retinoic acid inducible gene-I (RIG-I) and the mitochondrial antiviral signaling (MAVS) pathway. MuV-induced IFNs were strongly upregulated in PKR-knockdown cells. MuV-induced SG formation was suppressed by knockdown of PKR and SG marker proteins, Ras-GTPase-activating protein SH3-domain-binding protein 1 and T-cell-restricted intracellular antigen-1, and significantly increased the levels of MuV-induced IFN-λ1. However, viral titer was not altered by suppression of SG formation. PKR was required for induction of SGs by MuV infection and regulated type III IFN (IFN-λ1) mRNA stability. MuV-induced SGs partly suppressed type III IFN production by MuV; however, the limited suppression was not sufficient to inhibit MuV replication in cell culture. Our results provide insight into the relationship between SGs and IFN production induced by MuV infection. PMID:27560627

  18. Mumps Virus Induces Protein-Kinase-R-Dependent Stress Granules, Partly Suppressing Type III Interferon Production.

    PubMed

    Hashimoto, Shin; Yamamoto, Soh; Ogasawara, Noriko; Sato, Toyotaka; Yamamoto, Keisuke; Katoh, Hiroshi; Kubota, Toru; Shiraishi, Tsukasa; Kojima, Takashi; Himi, Tetsuo; Tsutsumi, Hiroyuki; Yokota, Shin-Ichi

    2016-01-01

    Stress granules (SGs) are cytoplasmic granular aggregations that are induced by cellular stress, including viral infection. SGs have opposing antiviral and proviral roles, which depend on virus species. The exact function of SGs during viral infection is not fully understood. Here, we showed that mumps virus (MuV) induced SGs depending on activation of protein kinase R (PKR). MuV infection strongly induced interferon (IFN)-λ1, 2 and 3, and IFN-β through activation of IFN regulatory factor 3 (IRF3) via retinoic acid inducible gene-I (RIG-I) and the mitochondrial antiviral signaling (MAVS) pathway. MuV-induced IFNs were strongly upregulated in PKR-knockdown cells. MuV-induced SG formation was suppressed by knockdown of PKR and SG marker proteins, Ras-GTPase-activating protein SH3-domain-binding protein 1 and T-cell-restricted intracellular antigen-1, and significantly increased the levels of MuV-induced IFN-λ1. However, viral titer was not altered by suppression of SG formation. PKR was required for induction of SGs by MuV infection and regulated type III IFN (IFN-λ1) mRNA stability. MuV-induced SGs partly suppressed type III IFN production by MuV; however, the limited suppression was not sufficient to inhibit MuV replication in cell culture. Our results provide insight into the relationship between SGs and IFN production induced by MuV infection. PMID:27560627

  19. 46 CFR 160.037-4 - Approval and production tests.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... MATERIALS: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Hand Orange Smoke Distress Signals § 160.037-4... sources of raw materials, or (iii) The start of production on a new production line or on a previously... procedures must include inspection of materials entering into construction of the signals and inspection...

  20. 46 CFR 160.021-4 - Approval and production tests.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... MATERIALS: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Hand Red Flare Distress Signals § 160.021-4... sources of raw materials, or (iii) the start of production on a new production line or on a previously... procedures must include inspection of materials entering into construction of the signals and inspection...

  1. 46 CFR 57.06-1 - Production test plate requirements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 2 2012-10-01 2012-10-01 false Production test plate requirements. 57.06-1 Section 57.06-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING WELDING AND BRAZING Production Tests § 57.06-1 Production test plate requirements. (a) Production test plates shall...

  2. 46 CFR 57.06-1 - Production test plate requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Production test plate requirements. 57.06-1 Section 57.06-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING WELDING AND BRAZING Production Tests § 57.06-1 Production test plate requirements. (a) Production test plates shall...

  3. 46 CFR 57.06-1 - Production test plate requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 2 2011-10-01 2011-10-01 false Production test plate requirements. 57.06-1 Section 57.06-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING WELDING AND BRAZING Production Tests § 57.06-1 Production test plate requirements. (a) Production test plates shall...

  4. 46 CFR 57.06-1 - Production test plate requirements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 2 2014-10-01 2014-10-01 false Production test plate requirements. 57.06-1 Section 57.06-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING WELDING AND BRAZING Production Tests § 57.06-1 Production test plate requirements. (a) Production test plates shall...

  5. 46 CFR 57.06-1 - Production test plate requirements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 2 2013-10-01 2013-10-01 false Production test plate requirements. 57.06-1 Section 57.06-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING WELDING AND BRAZING Production Tests § 57.06-1 Production test plate requirements. (a) Production test plates shall...

  6. Hybrid III Lower Leg Injury Assessment Reference Curves Under Axial Impacts Using Matched-Pair Tests.

    PubMed

    Yoganandan, Narayan; Pintar, Frank; Banerjee, Anjishnu; Schlick, Michael; Chirvi, Sajal; Uppal, Hermeeth; Merkle, Andrew; Voo, Liming; Kleinberg, Michael

    2015-01-01

    The objective of the present study was to derive injury probability curves applicable to the Hybrid III dummy (also termed the Anthropomorphic Test Device, ATD) lower leg under axial impacts for military applications. A matched-pair approach was used. Axial impacts were delivered to below knee foot-ankle complex preparations of the lower leg of the ATD using pendulum and custom vertical accelerator devices. Military boot was used in some tests. Post mortem human surrogate (PMHS) preparations were used as matched-pair tests for injury outcomes. The alignment was such that the foot-ankle complex was orthogonal to the leg (below knee tibia-fibula complex), termed as the normal 90-90 posture. Injury outcomes from the biological surrogate focused on calcaneus and or distal tibia fractures with or without the involvement of articular surfaces. Peak lower tibia load cell forces were obtained from matched-pair dummy tests. Injury and force data were paired, censoring was assigned based on injury outcomes and survival analysis was done using the Weibull distribution to derive dummy-based probability curves. Mean peak forces were extracted at 5, 10, 20 and 50% probability levels. Normalized confidence interval sizes (NCIS) at ± 95% level were computed to determine the tightness-of-fit of the confidence bands. The NCIS data ranged from 0.34 to 0.78 and a peak force of 8.2 kN was associated at the ten percent injury probability level. Other data and curves are given in the body of the paper. The present Injury Assessment Reference Curves and Values (IARC and IARV) may be used in future tests for advancing safety in military environments. These survival analysis processes and IARC and IARV data may also be used in other applications. PMID:25996722

  7. Characterization of the Edge Crack Torsion (ECT) Test for Mode III Fracture Toughness Measurement of Laminated Composites

    NASA Technical Reports Server (NTRS)

    Ratcliffe, James G.

    2004-01-01

    The edge crack torsion (ECT) test is designed to initiate mode III delamination growth in composite laminates. An ECT specimen is a rectangular laminate, containing an edge delamination at the laminate mid-plane. Torsion load is applied to the specimens, resulting in relative transverse shear sliding of the delaminated faces. The test data reduction schemes are intended to yield initiation values of critical mode III strain energy release rate, G(sub IIIc), that are constant with delamination length. The test has undergone several design changes during its development. The objective of this paper was to determine the suitability of the current ECT test design as a mode III fracture test. To this end, ECT tests were conducted on specimens manufactured from IM7/8552 and specimens made from S2/8552 tape laminates. Several specimens, each with different delamination lengths are tested. Detailed, three-dimensional finite element analyses of the specimens were performed. The analysis results were used to calculate the distribution of mode I, mode II, and mode III strain energy release rate along the delamination front. The results indicated that mode III-dominated delamination growth would be initiated from the specimen center. However, in specimens of both material types, the measured values of G(sub IIIc) exhibited significant dependence on delamination length. Furthermore, there was a large amount of scatter in the data. Load-displacement response of the specimens exhibited significant deviation from linearity before specimen failure. X-radiographs of a sample of specimens revealed that damage was initiated in the specimens prior to failure. Further inspection of the failure surfaces is required to identify the damage and determine that mode III delamination is initiated in the specimens.

  8. Comparison of the developmental tests Bayley-III and Bayley-II in 7-month-old infants born preterm.

    PubMed

    Reuner, Gitta; Fields, Anna Christine; Wittke, Andrea; Löpprich, Martin; Pietz, Joachim

    2013-03-01

    The study aims on comparing Bayley Scales of infant development third (Bayley-III) and Bayley second (Bayley-II) edition with special focus on patterns in the first year of life. Fifty-five premature infants (43 with low birth weight/LBW >1,499 g and 12 with very/extremely low birth weight/VLBW/ELBW <1,500 g) aged 7 months (corrected for prematurity) were assessed with the complete Bayley-III. From this assessment, Bayley-II results were retrospectively estimated. Bayley-III results were compared to the expected mean with one-sample t-tests. The mean scores of both editions were compared with the aid of paired-sample t-tests. Pearson correlations between subscales and editions were analysed. The Bayley-III cognitive score of the study group was significantly higher than the expected mean of the standardization sample. VLBW/ELBW had significantly lower motor scores than LBW in both editions. When compared to estimated Bayley-II scores, all relevant Bayley-III scores were significantly higher (all p < .01) with highest difference (ten points) between the motor scales of both editions. There were significant correlations not only between Bayley-III cognitive and language scales but also between language and motor scales. Given the strong association between motor and cognitive behaviour in early infancy, this age-specific pattern is heightening the risk of failure to identify infants at risk for both cognitive and motor delay. Therefore, assessment of infants should comprise all subscales. Since Bayley-III probably overestimates especially motor performance in young infants, when interpreting Bayley-III scores in this age, comparison groups are highly recommended until further validation of normative data are outstanding. PMID:23224346

  9. Development and testing of commercial-scale, coal-fired combustion systems: Phase III. Final report

    SciTech Connect

    1996-03-01

    Based on studies that indicated a large potential for significantly increased coal-firing in the commercial sector, the U.S. Department of Energy`s Pittsburgh Energy Technology Center (PETC) sponsored a multi-phase development effort for advanced coal combustion systems. This Final Report presents the results of the last phase (Phase III) of a project for the development of an advanced coal-fired system for the commercial sector of the economy. The project performance goals for the system included dual-fuel capability (i.e., coal as primary fuel and natural gas as secondary fuel), combustion efficiency exceeding 99 percent, thermal efficiency greater than 80 percent, turndown of at least 3:1, dust-free and semi-automatic dry ash removal, fully automatic start-up with system purge and ignition verification, emissions performance exceeding New Source Performance Standards (NSPS) and approaching those produced by oil-fired, Commercial-sized units, and reliability, safety, operability, maintainability, and service life comparable to oil-fired units. The program also involved a site demonstration at a large facility owned by Striegel Supply Company, a portion of which was leased to MTCI. The site, mostly warehouse space, was completely unheated and the advanced coal-fired combustion system was designed and sized to heat this space. Three different coals were used in the project, one low and one high sulfur pulverized Pittsburgh No. 8 coal, and a micronized low volatile, bituminous coal. The sorbents used were Pfizer dolomitic limestone and an Anvil lime. More than 100 hours of screening test`s were performed to characterize the system. The parameters examined included coal firing rate, excess air level, ash recycle rate, coal type, dolomitic limestone feed rate, and steam injection rate. These tests indicated that some additional modifications for coal burning in the system were required.

  10. Test-retest reliability of UPDRS-III, dyskinesia scales, and timed motor tests in patients with advanced Parkinson's disease: an argument against multiple baseline assessments.

    PubMed

    Metman, Leo Verhagen; Myre, Brian; Verwey, Niek; Hassin-Baer, Sharon; Arzbaecher, Jean; Sierens, Diane; Bakay, Roy

    2004-09-01

    The primary objective of this study was to assess the intra-rater reliability of the motor section of the Unified Parkinson's Disease Rating Scale (UPDRS-III) in patients with advanced Parkinson's disease (PD). The secondary objective was to assess the intra-rater reliability of standard timed motor tests and dyskinesia scales to determine the necessity of multiple baseline core evaluations before surgery for PD. We carried out two standardized preoperative core evaluations of patients with advanced PD scheduled to undergo deep brain stimulation. Patients were examined in the defined off and on conditions by the same rater. UPDRS-III, timed tests, and dyskinesia scores from the two evaluations were compared using Wilcoxon Signed Ranks tests and intraclass correlation coefficients (ICC). Differences in UPDRS-III scores for the two visits were clinically and statistically nonsignificant, and the ICC was 0.9. Similarly, there were no significant differences in timed motor tests or dyskinesia scores, with a median ICC of 0.8. The results indicate that previous findings of high test-retest reliability of UPDRS-III in early untreated PD patients can now be extended to those with advanced disease complicated by motor fluctuations. In addition, test-retest reliability of dyskinesia scales and timed motor tests was high. Taken together, these findings challenge the need for multiple baseline assessments as currently stipulated in core assessment protocols for surgical intervention in PD. PMID:15372601

  11. Characterization of the Edge Crack Torsion (ECT) Test for Mode III Fracture Toughness Measurement of Laminated Composites

    NASA Technical Reports Server (NTRS)

    Ratcliffe, James G.

    2004-01-01

    The edge crack torsion (ECT) test is designed to initiate mode III delamination growth in composite laminates. The test has undergone several design changes during its development. The objective of this paper was to determine the suitability of the current ECT test design a mode III fracture test. To this end, ECT tests were conducted on specimens manufactured from IM7/8552 and S2/8552 tape laminates. Three-dimensional finite element analyses were performed. The analysis results were used to calculate the distribution of mode I, mode II, and mode III strain energy release rate along the delamination front. The results indicated that mode IIIdominated delamination growth would be initiated from the specimen center. However, in specimens of both material types, the measured values of GIIIc exhibited significant dependence on delamination length. Load-displacement response of the specimens exhibited significant deviation from linearity before specimen failure. X-radiographs of a sample of specimens revealed that damage was initiated in the specimens prior to failure. Further inspection of the failure surfaces is required to identify the damage and determine that mode III delamination is initiated in the specimens.

  12. SAGE III

    Atmospheric Science Data Center

    2016-06-15

    SAGE III Data and Information The Stratospheric Aerosol and Gas ... on the spacecraft. SAGE III produced L1 and L2 scientific data from 5/07/2002 until 12/31/2005. The flight of the second instrument is as ... Guide Documents:  Project Guide Data Products User's Guide  (PDF) Relevant Documents:  ...

  13. Rebamipide inhibits ceramide-induced interleukin-8 production in Kato III human gastric cancer cells.

    PubMed

    Masamune, A; Yoshida, M; Sakai, Y; Shimosegawa, T

    2001-08-01

    Helicobacter pylori adheres to gastric epithelial cells and stimulates interleukin-8 production. Ceramide, a lipid second messenger, has become known as an important mediator of some actions of several cytokines. We have recently reported that H. pylori-dependent ceramide production may activate nuclear factor-kappaB and mediate interleukin-8 expression in human gastric cancer cell lines. In this study, we evaluated the effect of rebamipide, an antigastritis and antiulcer agent, on H. pylori-dependent ceramide production and subsequent interleukin-8 expression in Kato III cells. Rebamipide inhibited ceramide-induced interleukin-8 expression in a dose-dependent manner. Rebamipide decreased the ceramide-induced increase of the interleukin-8 mRNA level as assessed by Northern blotting. Rebamipide suppressed interleukin-8 gene transcription and nuclear factor-kappaB-dependent transcriptional activity as assessed by luciferase assay. Rebamipide inhibited the ceramide-induced degradation of IkappaB-alpha (a major cytoplasmic inhibitor of nuclear factor-kappaB), further supporting that rebamipide inhibits the activation of nuclear factor-kappaB. Rebamipide also inhibited the ceramide-dependent activation of mitogen-activated protein kinases. Furthermore, rebamipide significantly attenuated the H. pylori-dependent increase in the intracellular ceramide level. These results suggest a novel mechanism by which rebamipide may protect against the mucosal inflammation associated with H. pylori infection. PMID:11454909

  14. Individualized Testing System: Performance Assessment Resources, ISCS Level III, IO-WU.

    ERIC Educational Resources Information Center

    Hathway, James A., Ed.

    This is one of four performance assessment resources booklets for Level III of the Intermediate Science Curriculum Study (ISCS). The four booklets are considered one of four major subdivisions of a set of individualized evaluation materials for Level III developed as a part of the ISCS Individualized Teacher Preparation (ITP) program. Each of…

  15. Individualized Testing System: Performance Assessment Resources, ISCS Level III, WYY-IV.

    ERIC Educational Resources Information Center

    Hathway, James A., Ed.

    This is one of four performance assessment resources booklets for Level III of the Intermediate Science Curriculum Study (ISCS). The four booklets are considered one of four major subdivisions of a set of individualized evaluation materials for Level III developed as a part of the ISCS Individualized Teacher Preparation (ITP) program. Each of…

  16. Individualized Testing System: Performance Assessment Resources, ISCS Level III, ES-WB.

    ERIC Educational Resources Information Center

    Hathway, James A., Ed.

    This is one of four performance assessment resources booklets for Level III of the Intermediate Science Curriculum Study (ISCS). The four booklets are considered one of four major subdivisions of a set of individualized evaluation materials for Level III developed as a part of the ISCS Individualized Teacher Preparation (ITP) program. Each of…

  17. Individualized Testing System: Performance Assessment Resources, ISCS Level III, WW-CP.

    ERIC Educational Resources Information Center

    Hathway, James A., Ed.

    This is one of four performance assessment resources booklets for Level III of the Intermediate Science Curriculum Study (ISCS). The four booklets are considered one of four major subdivisions of a set of individualized evaluation materials for Level III developed as a part of the ISCS Individualized Teacher Preparation (ITP) program. Each of…

  18. 46 CFR 57.06-5 - Production toughness testing.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 2 2014-10-01 2014-10-01 false Production toughness testing. 57.06-5 Section 57.06-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING WELDING AND BRAZING Production Tests § 57.06-5 Production toughness testing. (a) In addition to the test specimens required...

  19. 46 CFR 57.06-5 - Production toughness testing.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Production toughness testing. 57.06-5 Section 57.06-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING WELDING AND BRAZING Production Tests § 57.06-5 Production toughness testing. (a) In addition to the test specimens required...

  20. 46 CFR 57.06-5 - Production toughness testing.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 2 2013-10-01 2013-10-01 false Production toughness testing. 57.06-5 Section 57.06-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING WELDING AND BRAZING Production Tests § 57.06-5 Production toughness testing. (a) In addition to the test specimens required...

  1. 46 CFR 57.06-5 - Production toughness testing.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 2 2012-10-01 2012-10-01 false Production toughness testing. 57.06-5 Section 57.06-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING WELDING AND BRAZING Production Tests § 57.06-5 Production toughness testing. (a) In addition to the test specimens required...

  2. 46 CFR 57.06-5 - Production toughness testing.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 2 2011-10-01 2011-10-01 false Production toughness testing. 57.06-5 Section 57.06-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING WELDING AND BRAZING Production Tests § 57.06-5 Production toughness testing. (a) In addition to the test specimens required...

  3. Fire Fighter Level I-II-III [and] Practical Skills Test. Wisconsin Fire Service Certification Series. Final Revision.

    ERIC Educational Resources Information Center

    Pribyl, Paul F.

    Practical skills tests are provided for fire fighter trainees in the Wisconsin Fire Service Certification Series, Fire Fighter Levels I, II, and III. A course introduction appears first and contains this information: recommended instructional sequence, required facilities, instructional methodology, requirements for certification, course…

  4. 46 CFR 57.06-4 - Production testing specimen requirements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... WELDING AND BRAZING Production Tests § 57.06-4 Production testing specimen requirements. (a) For test... to welding shall not throw the finished test plate out of line by an angle of over 5°. (c) Where the welding has warped the test plates, the plates shall be straightened before being stress-relieved....

  5. 46 CFR 57.06-4 - Production testing specimen requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... WELDING AND BRAZING Production Tests § 57.06-4 Production testing specimen requirements. (a) For test... to welding shall not throw the finished test plate out of line by an angle of over 5°. (c) Where the welding has warped the test plates, the plates shall be straightened before being stress-relieved....

  6. 46 CFR 57.06-4 - Production testing specimen requirements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... WELDING AND BRAZING Production Tests § 57.06-4 Production testing specimen requirements. (a) For test... to welding shall not throw the finished test plate out of line by an angle of over 5°. (c) Where the welding has warped the test plates, the plates shall be straightened before being stress-relieved....

  7. 46 CFR 57.06-4 - Production testing specimen requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... WELDING AND BRAZING Production Tests § 57.06-4 Production testing specimen requirements. (a) For test... to welding shall not throw the finished test plate out of line by an angle of over 5°. (c) Where the welding has warped the test plates, the plates shall be straightened before being stress-relieved....

  8. 46 CFR 57.06-4 - Production testing specimen requirements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... WELDING AND BRAZING Production Tests § 57.06-4 Production testing specimen requirements. (a) For test... to welding shall not throw the finished test plate out of line by an angle of over 5°. (c) Where the welding has warped the test plates, the plates shall be straightened before being stress-relieved....

  9. Heterogeneous Reduction of PuO2 with Fe(II): Importance of the Fe(III) Reaction Product

    SciTech Connect

    Felmy, Andrew R.; Moore, Dean A.; Rosso, Kevin M.; Qafoku, Odeta; Rai, Dhanpat; Buck, Edgar C.; Ilton, Eugene S.

    2011-05-01

    Abstract Heterogeneous reduction of actinides in higher and more soluble oxidation states to lower more insoluble oxidation states by reductants such as Fe(II) has been the subject of intensive study for more than two decades. However, Fe(II)-induced reduction of sparingly soluble Pu(IV) to the more soluble lower oxidation state Pu(III) has been much less studied even though such reactions can potentially increase the mobility of Pu in the subsurface. Thermodynamic calculations are presented that show how differences in the free energy of various possible solid-phase Fe(III) reaction products can greatly influence aqueous Pu(III) concentrations resulting from reduction of PuO2(am) by Fe(II). We present the first experimental evidence that reduction of PuO2(am) to Pu(III) by Fe(II) was enhanced when the Fe(III) mineral goethite was spiked into the reaction. The effect of goethite on reduction of Pu(IV) was demonstrated by measuring the time-dependence of total aqueous Pu concentration, its oxidation state, and system pe/pH. We also re-evaluated established protocols for determining Pu(III) [(Pu(III) + Pu(IV)) - Pu(IV)] by using thenoyltrifluoroacetone (TTA) in toluene extractions; the study showed that it is important to eliminate dissolved oxygen from the TTA solutions for accurate determinations. More broadly, this study highlights the importance of the Fe(III) reaction product in actinide reduction rate and extent by Fe(II).

  10. A Review and Comparison of the Reliabilities of the MMPI-2, MCMI-III, and PAI Presented in Their Respective Test Manuals

    ERIC Educational Resources Information Center

    Wise, Edward A.; Streiner, David L.; Walfish, Steven

    2010-01-01

    This article provides a review of the literature to determine the most frequently used personality tests. Based on this review, internal consistency and test-retest reliability coefficients from the test manuals for the Minnesota Multiphasic Personality Inventory-2 (MMPI-2), Millon Clinical Multiaxial Inventory-III (MCMI-III), and Personality…

  11. 46 CFR 160.022-4 - Approval and production tests.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... MATERIALS: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Floating Orange Smoke Distress Signals (5... construction details, (ii) Any change in sources of raw materials, or (iii) The start of production on a new... manufacturer. The manufacturer's quality control procedures must include inspection of materials entering...

  12. 46 CFR 160.057-4 - Approval and production tests.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... MATERIALS: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Floating Orange Smoke Distress Signals (15... construction details, (ii) any change in sources of raw materials, or (iii) the start of production on a new... manufacturer. The manufacturer's quality control procedures must include inspection of materials entering...

  13. Iminophosphorane-organogold(III) complexes induce cell death through mitochondrial ROS production

    PubMed Central

    Vela, Laura; Contel, María; Palomera, Luis; Azaceta, Gemma; Marzo, Isabel

    2011-01-01

    Gold compounds are being investigated as potential antitumor drugs. Some gold(III) derivatives have shown to induce cell death in solid tumors but their mechanism of action differs from that of cisplatin, since most of these compounds do not bind to DNA. We have explored cellular events triggered by three different iminophosphorane-organo gold(III) compounds in leukemia cells (a neutral compound with two chloride ligands [Au{κ2-C,N-C6H4(PPh2=N(C6H5)-2}Cl2] 1, and two cationic compounds with either a dithiocarbamate ligand [Au{κ2-C,N-C6H4(PPh2=N(C6H5)-2}(S2CN-Me2)]PF6 2, or a water-soluble phosphine and a chloride ligand [Au{κ2-C,N-C6H4(PPh2=N(C6H5)-2}(P{Cp(m-C6H4-SO3Na)2}3) Cl]PF6 3). All three compounds showed higher toxicity against leukemia cells when compared to normal T-lymphocytes. Compounds 1 and 2 induced both necrosis and apoptosis, while 3 was mainly apoptotic. Necrotic cell death induced by 1 and 2 was Bax/Bak- and caspase-independent, while apoptosis induced by 3 was Bax/Bak-dependent. Reactive oxygen species (ROS) production at the mitochondrial level was a critical step in the antitumor effect of these compounds. PMID:21864808

  14. SUNLIGHT AND IRON(III)-INDUCED PHOTOCHEMICAL PRODUCTION OF DISSOLVED GASEOUS MERCURY IN FRESHWATER. (R827632)

    EPA Science Inventory

    Mechanistic understanding of sunlight-induced natural processes for
    production of dissolved gaseous mercury (DGM) in freshwaters has remained
    limited, and few direct field tests of the mechanistic hypotheses are available.
    We exposed ferric iron salt-spiked fresh s...

  15. DEVELOPING A FRAMEWORK FOR TESTING INDOOR AIR PRODUCTS

    EPA Science Inventory

    The paper discusses the development of a framework for testing products used indoors for appropriate environmental attributes, as part of EPA's Environmental Technology Verification (ETV) program. Test protocols are being established for products that fit into three categories: ...

  16. 46 CFR 160.174-25 - Production testing.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 6 2011-10-01 2011-10-01 false Production testing. 160.174-25 Section 160.174-25...: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Thermal Protective Aids § 160.174-25 Production testing. (a) Thermal protective aid production testing is conducted under the procedures in this section and...

  17. 46 CFR 159.007-9 - Production inspections and tests.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 6 2010-10-01 2010-10-01 false Production inspections and tests. 159.007-9 Section 159... MATERIALS: SPECIFICATIONS AND APPROVAL APPROVAL OF EQUIPMENT AND MATERIALS Production Inspection and Tests of Approved Equipment and Materials § 159.007-9 Production inspections and tests. (a) If...

  18. 46 CFR 160.031-5 - Approval and production tests.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...'s quality control procedures must include the inspection of appliances during production as well as... 46 Shipping 6 2010-10-01 2010-10-01 false Approval and production tests. 160.031-5 Section 160.031... Equipment) § 160.031-5 Approval and production tests. (a) Approval test. An independent laboratory...

  19. 46 CFR 160.040-5 - Approval and production tests.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... manufacturer's quality control procedures must include the inspection of appliances during production as well... 46 Shipping 6 2010-10-01 2010-10-01 false Approval and production tests. 160.040-5 Section 160.040... Rocket Type (and Equipment) § 160.040-5 Approval and production tests. (a) Approval tests. An...

  20. QCD corrections to pair production of Type III Seesaw leptons at hadron colliders

    NASA Astrophysics Data System (ADS)

    Ruiz, Richard

    2015-12-01

    If kinematically accessible, hadron collider experiments provide an ideal laboratory for the direct production of heavy lepton partners in Seesaw models. In the context of the Type III Seesaw Mechanism, the O({α}_s) rate and shape corrections are presented for the pair production of hypothetical, heavy SU(2) L triplet leptons in pp collisions at √{s} = 13, 14 and 100TeV. The next-to-leading order (NLO) K-factors span, approximately, K NLO = 1 .1 - 1 .4 for both charged current and neutral current processes over a triplet mass range m T = 100 GeV - 2 TeV. Total production cross sections exhibit a - 6 % + 5 % scale dependence at 14 TeV and ±1% at 100 TeV. The NLO differential K-factors for heavy lepton kinematics are largely flat, suggesting that na¨ıve scaling by the total K NLO is reasonably justified. The resummed transverse momentum distribution of the dilepton system is presented at leading logarithmic (LL) accuracy. The effects of resummation are large in TeV-scale dilepton systems. Discovery potential to heavy lepton pairs at 14 and 100 TeV is briefly explored: at the High-Luminosity LHC, we estimate a 4 .8 - 6 .3 σ discovery potential maximally for m T = 1 .5 - 1 .6 TeV after 3000 fb-1. With 300 (3000) fb-1, there is 2σ sensitivity up to m T = 1 .3 - 1 .4 TeV (1 .7 - 1 .8 TeV) in the individual channels. At 100 TeV and with 10 fb-1, a 5 σ discovery can be achieved for m T = 1 .4 - 1 .6 TeV. Due to the factorization properties of Drell-Yan-type systems, the fixed order and resummed calculations reduce to convolutions over tree-level quantities.

  1. English Language Proficiency and Test Performance: An Evaluation of Bilingual Students with the Woodcock-Johnson III Tests of Cognitive Abilities

    ERIC Educational Resources Information Center

    Sotelo-Dynega, Marlene; Ortiz, Samuel O.; Flanagan, Dawn P.; Chaplin, William F.

    2013-01-01

    In this article, we report the findings of an exploratory empirical study that investigated the relationship between English Language Proficiency (ELP) on performance on the Woodcock-Johnson Tests of Cognitive Abilities-Third Edition (WJ III) when administered in English to bilingual students of varying levels of ELP. Sixty-one second-grade…

  2. Analysis of WISC-III, Stanford-Binet:IV, and academic achievement test scores in children with autism.

    PubMed

    Mayes, Susan Dickerson; Calhoun, Susan L

    2003-06-01

    Nonverbal IQs were greater than verbal IQs for young children (3-7 years of age) on the Stanford-Binet:IV (n = 53). However, WISC-III verbal and nonverbal IQs were similar for older children, 6-15 years of age (n = 63). Stanford-Binet:IV profiles were generally consistent for the low-IQ (< 80) and high-IQ (> or = 80) groups, with high scores on visual matching tests (Bead Memory and Quantitative Reasoning). The low- and high-WISC-III IQ groups both performed well relative to IQ on tests of lexical knowledge (Similarities, Information, and Vocabulary), but not on language comprehension and social reasoning (Comprehension). The low-IQ group did best on visuo-motor subtests (Object Assembly and Block Design), but the high-IQ group did not. The high-IQ group had significantly low scores on the Digit Span, Arithmetic, Coding, VMI, and WIAT Written Expression tests, suggesting attention and writing weaknesses.

  3. Vegetation productivity during Termination III inferred from a speleothem δ13C record (Ejulve Cave, NE Spain)

    NASA Astrophysics Data System (ADS)

    Perez-Mejías, Carlos; Moreno, Ana; Sancho, Carlos; Bartolomé, Miguel; Stoll, Heather; Cacho, Isabel; Cheng, Hai; Edwards, R. Lawrence

    2016-04-01

    The timing of Termination III, in contrast to TI and TII, is poorly known. Although TIII has been described in pollen sequences from marine cores whose chronology was tuned to orbital parameters, only few continental records with absolute dates have been published. Then, new records of this period are particularly required to test the hypothetical synchronicity at planetary scale of this event or to explore leads and lags between different proxies. Here we present the record of ARTEMISA stalagmite from Ejulve cave (NE Spain) that covers this period with exceptional resolution and constrained by a robust chronological framework obtained from 24 U-Th dates. The largest shift in δ13C record (3 per mil of variation) occurs at 241±2.3 kyr evidencing the TIII inception, in agreement with both Sanbao Cave record in China (within age uncertainties) and the shift to interglacial values of CH4 and CO2 in Antarctica, thus supporting its global synchrony. Interpreting δ13C data in Ejulve Cave is supported by 3 years of monitoring tasks allowing the association of this proxy with vegetation productivity. Thus, more positive values of δ13C, together with higher values in Mg/Ca and Sr/Ca in present-day farmed calcite occurred during dry summer seasons. Besides, these periods are also characterized by the lowest amount of calcite precipitating in the cave. On the contrary, more negative values are obtained during wetter periods, even if they are cooler, showing the highest calcite precipitation rates. During TIII, a spectacular increase in growth rate in the stalagmite is observed, that reaches its maximum (20-30 mm/kyr) during the following 4 kyr. Coherently, both δ13C and trace elements ratios (Mg/Ca and Sr/Ca) mark an increase in humidity at 242 kyr that would last until 227 kyr BP delineating the duration of Stage 7e in this Mediterranean region. Other dry events highlighted by this record are shown at 247 kyr, 245-243 kyr and 221-219 kyr BP suggesting periods of forest

  4. Validation of the 5th and 95th Percentile Hybrid III Anthropomorphic Test Device Finite Element Model

    NASA Technical Reports Server (NTRS)

    Lawrence, C.; Somers, J. T.; Baldwin, M. A.; Wells, J. A.; Newby, N.; Currie, N. J.

    2014-01-01

    NASA spacecraft design requirements for occupant protection are a combination of the Brinkley criteria and injury metrics extracted from anthropomorphic test devices (ATD's). For the ATD injury metrics, the requirements specify the use of the 5th percentile female Hybrid III and the 95th percentile male Hybrid III. Furthermore, each of these ATD's is required to be fitted with an articulating pelvis and a straight spine. The articulating pelvis is necessary for the ATD to fit into spacecraft seats, while the straight spine is required as injury metrics for vertical accelerations are better defined for this configuration. The requirements require that physical testing be performed with both ATD's to demonstrate compliance. Before compliance testing can be conducted, extensive modeling and simulation are required to determine appropriate test conditions, simulate conditions not feasible for testing, and assess design features to better ensure compliance testing is successful. While finite element (FE) models are currently available for many of the physical ATD's, currently there are no complete models for either the 5th percentile female or the 95th percentile male Hybrid III with a straight spine and articulating pelvis. The purpose of this work is to assess the accuracy of the existing Livermore Software Technology Corporation's FE models of the 5th and 95th percentile ATD's. To perform this assessment, a series of tests will be performed at Wright Patterson Air Force Research Lab using their horizontal impact accelerator sled test facility. The ATD's will be placed in the Orion seat with a modified-advanced-crew-escape-system (MACES) pressure suit and helmet, and driven with loadings similar to what is expected for the actual Orion vehicle during landing, launch abort, and chute deployment. Test data will be compared to analytical predictions and modelling uncertainty factors will be determined for each injury metric. Additionally, the test data will be used to

  5. 16 CFR 1212.16 - Production testing.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... manufactured, to demonstrate that the multi-purpose lighters meet the specifications, required under § 1212.15... that any multi-purpose lighters manufactured during the production interval may not meet the standard..., the equipment used to manufacture the product, or the product's materials or design. The...

  6. [Detection of carriers of hemophilia A by testing for HindIII polymorphism in the factor VIII gene by PCR].

    PubMed

    Surin, V L; Aseev, M V; Zhukova, E L; Baranov, V S; Solov'ev, G Ia; Grineva, N I; Andreeva, T A; Izhevskaia, V L; Likhacheva, E A; Pliushch, O P

    1990-10-01

    Representatives of 62 families from Moscow and Leningrad with haemophilia A observed in the pedigree were tested for HindIII polymorphism in the factor VIII gene. The proposed scheme of investigation was based on intron 19 of the FVIII gene amplification by the PCR technique followed by restriction analysis with the inner control of hydrolysis. 207 unrelated X-chromosomes were analysed, the frequency of the incidence of the polymorphic HindIII site in the given population found to be 0.29. The frequency of incidence of the HindIII heterozygotes calculated according to Hardy-Weinberg equation was 0.41. This value evidences for relatively high informativity of this polymorphism for carrier detection and prenatal diagnosis of haemophilia A. 23 families (37%) out of 62 examined in the study were informative for this criteria. The new scheme proved to be effective in testing HindIII polymorphism for haemophilia A carrier detection and prenatal diagnosis. The whole procedure takes one day, the radiolabelled probes are not used. The scheme described was inculcated in the All-Union Research Center for Haematology, Ministry of Health, USSR, Moscow, Research Institute for Obstetrics and Gynecology, Leningrad, Institute of Medical Genetics, Greifswald, DDR. PMID:2149345

  7. A Modified Edge Crack Torsion Test for Measurement of Mode III Fracture Toughness of Laminated Tape Composites

    NASA Technical Reports Server (NTRS)

    Czabaj, Michael W.; Davidson, Barry D.; Ratcliffe, James G.

    2016-01-01

    Modifications to the edge crack torsion (ECT) test are studied to improve the reliability of this test for measuring the mode-III fracture toughness, G (sub IIIc), of laminated tape fiber-reinforced polymeric (FRP) composites. First, the data reduction methods currently used in the ECT test are evaluated and deficiencies in their accuracy are discussed. An alternative data reduction technique, which uses a polynomial form to represent ECT specimen compliance solution, is evaluated and compared to FEA (finite element analysis) results. Second, seven batches of ECT specimens are tested, each batch containing specimens with a preimplanted midplane edge delamination and midplane plies with orientations of plus theta divided by minus theta, with theta ranging from 0 degrees to 90 degrees in 15-degree increments. Tests on these specimens show that intralaminar cracking occurs in specimens from all batches except for which theta = 15 degrees and 30 degrees. Tests on specimens of these two batches are shown to result in mode-III delamination growth at the intended ply interface. The findings from this study are encouraging steps towards the use of the ECT test as a standardized method for measuring G (sub IIIc), although further modification to the data reduction method is required to make it suitable for use as part of a standardized test method.

  8. Ultra-high-throughput Production of III-V/Si Wafer for Electronic and Photonic Applications

    NASA Astrophysics Data System (ADS)

    Geum, Dae-Myeong; Park, Min-Su; Lim, Ju Young; Yang, Hyun-Duk; Song, Jin Dong; Kim, Chang Zoo; Yoon, Euijoon; Kim, Sanghyeon; Choi, Won Jun

    2016-02-01

    Si-based integrated circuits have been intensively developed over the past several decades through ultimate device scaling. However, the Si technology has reached the physical limitations of the scaling. These limitations have fuelled the search for alternative active materials (for transistors) and the introduction of optical interconnects (called “Si photonics”). A series of attempts to circumvent the Si technology limits are based on the use of III-V compound semiconductor due to their superior benefits, such as high electron mobility and direct bandgap. To use their physical properties on a Si platform, the formation of high-quality III-V films on the Si (III-V/Si) is the basic technology ; however, implementing this technology using a high-throughput process is not easy. Here, we report new concepts for an ultra-high-throughput heterogeneous integration of high-quality III-V films on the Si using the wafer bonding and epitaxial lift off (ELO) technique. We describe the ultra-fast ELO and also the re-use of the III-V donor wafer after III-V/Si formation. These approaches provide an ultra-high-throughput fabrication of III-V/Si substrates with a high-quality film, which leads to a dramatic cost reduction. As proof-of-concept devices, this paper demonstrates GaAs-based high electron mobility transistors (HEMTs), solar cells, and hetero-junction phototransistors on Si substrates.

  9. Ultra-high-throughput Production of III-V/Si Wafer for Electronic and Photonic Applications

    PubMed Central

    Geum, Dae-Myeong; Park, Min-Su; Lim, Ju Young; Yang, Hyun-Duk; Song, Jin Dong; Kim, Chang Zoo; Yoon, Euijoon; Kim, SangHyeon; Choi, Won Jun

    2016-01-01

    Si-based integrated circuits have been intensively developed over the past several decades through ultimate device scaling. However, the Si technology has reached the physical limitations of the scaling. These limitations have fuelled the search for alternative active materials (for transistors) and the introduction of optical interconnects (called “Si photonics”). A series of attempts to circumvent the Si technology limits are based on the use of III-V compound semiconductor due to their superior benefits, such as high electron mobility and direct bandgap. To use their physical properties on a Si platform, the formation of high-quality III-V films on the Si (III-V/Si) is the basic technology ; however, implementing this technology using a high-throughput process is not easy. Here, we report new concepts for an ultra-high-throughput heterogeneous integration of high-quality III-V films on the Si using the wafer bonding and epitaxial lift off (ELO) technique. We describe the ultra-fast ELO and also the re-use of the III-V donor wafer after III-V/Si formation. These approaches provide an ultra-high-throughput fabrication of III-V/Si substrates with a high-quality film, which leads to a dramatic cost reduction. As proof-of-concept devices, this paper demonstrates GaAs-based high electron mobility transistors (HEMTs), solar cells, and hetero-junction phototransistors on Si substrates. PMID:26864968

  10. Ultra-high-throughput Production of III-V/Si Wafer for Electronic and Photonic Applications.

    PubMed

    Geum, Dae-Myeong; Park, Min-Su; Lim, Ju Young; Yang, Hyun-Duk; Song, Jin Dong; Kim, Chang Zoo; Yoon, Euijoon; Kim, SangHyeon; Choi, Won Jun

    2016-02-11

    Si-based integrated circuits have been intensively developed over the past several decades through ultimate device scaling. However, the Si technology has reached the physical limitations of the scaling. These limitations have fuelled the search for alternative active materials (for transistors) and the introduction of optical interconnects (called "Si photonics"). A series of attempts to circumvent the Si technology limits are based on the use of III-V compound semiconductor due to their superior benefits, such as high electron mobility and direct bandgap. To use their physical properties on a Si platform, the formation of high-quality III-V films on the Si (III-V/Si) is the basic technology ; however, implementing this technology using a high-throughput process is not easy. Here, we report new concepts for an ultra-high-throughput heterogeneous integration of high-quality III-V films on the Si using the wafer bonding and epitaxial lift off (ELO) technique. We describe the ultra-fast ELO and also the re-use of the III-V donor wafer after III-V/Si formation. These approaches provide an ultra-high-throughput fabrication of III-V/Si substrates with a high-quality film, which leads to a dramatic cost reduction. As proof-of-concept devices, this paper demonstrates GaAs-based high electron mobility transistors (HEMTs), solar cells, and hetero-junction phototransistors on Si substrates.

  11. Testing DSM-III symptom criteria for schizotypal and borderline personality disorders.

    PubMed

    McGlashan, T H

    1987-02-01

    Schizotypal and borderline personality disorders (SPD and BPD, respectively) appear to be different at follow-up, yet they are poorly discriminated from each other by current DSM-III symptom criteria. In the Chestnut Lodge Follow-up Study, three axis II study cohorts (pure SPD, n = 10; pure BPD, n = 81; mixed SPD/BPD, n = 18) with distinctive outcomes are defined using current borderline systems. This study compares the relative frequency with which individual symptom criteria from each system discriminate across study cohorts. Findings suggest that for SPD, the most characteristic (core) DSM-III symptoms are odd communication, suspiciousness/paranoid ideation, and social isolation, while the least discriminating symptom is illusions/depersonalization/derealization; the core DSM-III symptoms for BPD are unstable relationships, impulsivity, and self-damaging acts, while the least discriminating symptoms are inappropriate anger and intolerance of aloneness; depression as a symptom does not discriminate between SPD and BPD; and transient psychoses and brief paranoid experiences and/or regression in treatment discriminate for SPD but against BPD and therefore fit better as SPD criteria. Results support the retention of some, but the elimination of other, DSM-III symptom criteria for the diagnosis of SPD and BPD. PMID:3813809

  12. Analysis of WISC-III, Stanford-Binet: IV, and Academic Achievement Test Scores in Children with Autism.

    ERIC Educational Resources Information Center

    Mayes, Susan Dickerson; Calhoun, Susan L.

    2003-01-01

    Nonverbal IQs were greater than verbal IQs for children (ages 3-7) on the Stanford-Binet: IV (n=53). However, WISC-III verbal and nonverbal IQs were similar for older children, 6-15 years of age (n=63). Stanford-Binet: IV profiles were generally consistent for the low-IQ and high-IQ groups with high scores on visual matching tests. (Contains…

  13. 76 FR 69481 - Testing and Labeling Pertaining to Product Certification

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-08

    ... Testing Requirements for Children's Products (75 FR at 28342), we stated the following: If a high degree... continued testing for children's products. The final rule also establishes requirements for labeling of... is to reduce the incidents of deaths and injuries associated with children's products. This will...

  14. 49 CFR 178.33b-8 - Production tests.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 3 2013-10-01 2013-10-01 false Production tests. 178.33b-8 Section 178.33b-8... Containers, and Linings § 178.33b-8 Production tests. (a) Burst Testing. (1) One out of each lot of 5,000...,000 containers or less, successively produced per day, shall constitute a lot and if the...

  15. 78 FR 51678 - Market Tests of Experimental Postal Products

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-21

    ... 39 CFR Parts 3001 and 3035 Market Tests of Experimental Postal Products AGENCY: Postal Regulatory... Service filings concerning market tests of experimental products. The proposed rules address the contents of market test filings, describe how the filings will be reviewed, and discuss related matters....

  16. Dietary glycerol for quail: association between productive performance and COX III mRNA expression.

    PubMed

    Silva, S C C; Gasparino, E; Batista, E; Tanamati, F; Vesco, A P D; Lala, B; de Oliveira, D P

    2016-01-01

    This study was carry out to evaluate mRNA expression of mitochondrial cytochrome c oxidase III in the Pectoralis superficialis muscle of 28-day-old quails fed diets containing 0, 8, and 12% glycerol. Total RNA was extracted (N = 10) and cDNA was amplified using specifics primers for qRT-PCR. Feed efficiency and feed intake were evaluated. COX III mRNA expression in breast muscle was higher in the group fed with 12% glycerol (0.863 AU); no differences were observed in the expression of this gene between the muscle of animals fed diets without glycerol (0.357 AU) and 8% glycerol (0.415 AU). Quails that showed greater COX III mRNA expression also showed the lowest feed efficiency. These results show that there is a difference in COX III mRNA expression in breast muscle of 28-day-old quail fed diets different concentrations of glycerol. PMID:27323091

  17. Production of Apolipoprotein C-III Knockout Rabbits using Zinc Finger Nucleases

    PubMed Central

    Yang, Dongshan; Zhang, Jifeng; Xu, Jie; Zhu, Tianqing; Fan, Yanbo; Fan, Jianglin; Chen, Y. Eugene

    2013-01-01

    Apolipoprotein (Apo) C-III (ApoCIII) resides on the surface of plasma chylomicron (CM), very low density lipoprotein (VLDL) and high density lipoproteins (HDL). It has been recognized that high levels of plasma ApoCIII constitutea risk factor for cardiovascular diseases (CVD). Elevated plasma ApoCIII level often correlates with insulin resistance, obesity, and hypertriglyceridemia. Invaluable knowledge on the roles of ApoCIIIin lipid metabolisms and CVD has been obtained from transgenic mouse models including ApoCIII knockout (KO) mice; however, it is noted that the metabolism of lipoprotein in mice is different from that of humans in many aspects. It is not known until now whether elevated plasma ApoCIII is directly atherogenic. We worked to develop ApoCIII KO rabbits in the present study based on the hypothesis that rabbits can serve as a reasonablemodelfor studying human lipid metabolism and atherosclerosis. Zinc finger nuclease (ZFN) sets targeting rabbit ApoCIIIgene were subjected to in vitro validation prior to embryo microinjection. The mRNA was injected to the cytoplasm of 35 rabbit pronuclear stage embryos, and evaluated the mutation rates at the blastocyst state. Of sixteen blastocysts that were assayed, a satisfactory 50% mutation rate (8/16) at the targeting site was achieved, supporting the use of Set 1 for in vivo experiments. Next, we microinjected 145 embryos with Set 1 mRNA, and transferred these embryos to 7 recipient rabbits. After 30 days gestation, 21 kits were born, out of which five were confirmed as ApoCIII KO rabbits after PCR sequencing assays. The KO animal rate (#KO kits/total born) was 23.8%. The overall production efficiency is 3.4% (5 kits/145 embryos transferred). The present work demonstrated that ZFN is a highly efficient method to produce KO rabbits. These ApoCIII KO rabbits are novel resources to study the roles of ApoCIII in lipid metabolisms. PMID:24301055

  18. Propellant production on Mars - Single cell oxygen production test bed

    NASA Technical Reports Server (NTRS)

    Colvin, James; Schallhorn, Paul; Ramohalli, Kumar

    1991-01-01

    A study focusing on oxygen production using resources indigenous to Mars is presented. A bank of solid zirconia electrolytic cells that will electrochemically separate oxygen from a high temperature stream of carbon dioxide is at the center of the oxygen production system. The experimental data are discussed with attention given to the cell operating temperature, the carbon dioxide flow rate, and the voltage applied across the cell.

  19. Integrated Investigation on the Production and Fate of Organo-Cr(III) Complexes from Microbial Reduction of Chromate

    SciTech Connect

    Xun, Luying

    2004-06-01

    The screening of different genera of bacteria for production of soluble Cr(III) complexes has been completed. A total of eight organisms were screened for production of soluble Cr(III); three were Gram positive and five were Gram negative. The Gram positive bacteria were Cellulomonas sp. ES 6, Rhodococcus sp., and Leafsonia sp., while Shewanella. oneidensis MR 1, Desulfovibrio desulfuricans G20, D. vulgaris Hildenborough, Pseudomonas putida MK 1 and Ps. aeruginosa PAO 1 were Gram negative. S. oneidensis MR 1 and Cellulomonas sp ES 6 were grown in minimal media, GWM (Ground Water Medium with lactate/fumarate) and SGM (Simulated Groundwater Medium with sucrose), respectively. Other bacteria were screened under non-growth conditions with sucrose, lactate, or glycerol as electron donor. All experiments were carried out for a period of 15-30 days, with different organisms reaching a maximum soluble Cr(III) concentrations at different times: S. oneidensis, 2d; Cellulomonas sp., 8d; Leafsonia, 6d; Rhodococcus, 9d; Ps. putida MK 1, 6d, Ps. aeruginosa PAO 1, 3d; D. vulgaris Hildenborough, 3d; and D. desulfuricans G20, 21d. Initial characterization indicates that the soluble Cr(III) fraction produced by both S. oneidensis MR 1 and Cellulomonas sp. ES 6 passes through a 1-Kd cut off filter.

  20. Molten carbonate fuel cell product development test

    SciTech Connect

    Scroppo, J.A.; Camara, E.H.; Figueroa, R.A.

    1993-11-01

    M-C Power Corp. will design, fabricate, install, test, and evaluate a 250 kW Proof-of-Concept MCFC Power Plant. The plant will be located at Kaiser Permanente`s San Diego Medical Center; it will be designed and built by Bechtel Corp. Two 250 keV MCFC stacks will be assembled and tested at M-C Power; one stack will be used to support the San Diego field demonstration. This report outlines 6 tasks: project management/permitting, demonstration design, stack manufacturing, BOP fabrication, site work, and testing.

  1. Correlation of in vitro challenge testing with consumer use testing for cosmetic products.

    PubMed

    Brannan, D K; Dille, J C; Kaufman, D J

    1987-08-01

    An in vitro microbial challenge test has been developed to predict the likelihood of consumer contamination of cosmetic products. The challenge test involved inoculating product at four concentrations (30, 50, 70, and 100%) with microorganisms known to contaminate cosmetics. Elimination of these microorganisms at each concentration was followed over a 28-day period. The test was used to classify products as poorly preserved, marginally preserved, or well preserved. Consumer use testing was then used to determine whether the test predicted the risk of actual consumer contamination. Products classified by the challenge test as poorly preserved returned 46 to 90% contaminated after use. Products classified by the challenge test as well preserved returned with no contamination. Marginally preserved products returned with 0 to 21% of the used units contaminated. As a result, the challenge test described can be accurately used to predict the risk of consumer contamination of cosmetic products. PMID:3662517

  2. Correlation of in vitro challenge testing with consumer use testing for cosmetic products.

    PubMed Central

    Brannan, D K; Dille, J C; Kaufman, D J

    1987-01-01

    An in vitro microbial challenge test has been developed to predict the likelihood of consumer contamination of cosmetic products. The challenge test involved inoculating product at four concentrations (30, 50, 70, and 100%) with microorganisms known to contaminate cosmetics. Elimination of these microorganisms at each concentration was followed over a 28-day period. The test was used to classify products as poorly preserved, marginally preserved, or well preserved. Consumer use testing was then used to determine whether the test predicted the risk of actual consumer contamination. Products classified by the challenge test as poorly preserved returned 46 to 90% contaminated after use. Products classified by the challenge test as well preserved returned with no contamination. Marginally preserved products returned with 0 to 21% of the used units contaminated. As a result, the challenge test described can be accurately used to predict the risk of consumer contamination of cosmetic products. PMID:3662517

  3. Underground Test Area Subproject Phase I Data Analysis Task. Volume III - Groundwater Recharge and Discharge Data Documentation Package

    SciTech Connect

    1996-10-01

    Volume III of the documentation for the Phase I Data Analysis Task performed in support of the current Regional Flow Model, Transport Model, and Risk Assessment for the Nevada Test Site Underground Test Area Subproject contains the data covering groundwater recharge and discharge. Because of the size and complexity of the model area, a considerable quantity of data was collected and analyzed in support of the modeling efforts. The data analysis task was consequently broken into eight subtasks, and descriptions of each subtask's activities are contained in one of the eight volumes that comprise the Phase I Data Analysis Documentation.

  4. Rheological and molecular weight comparisons of approved hyaluronic acid products - preliminary standards for establishing class III medical device equivalence.

    PubMed

    Braithwaite, Gavin J C; Daley, Michael J; Toledo-Velasquez, David

    2016-01-01

    Hyaluronic acid of various molecular weights has been in use for the treatment of osteoarthritis knee pain for decades. Worldwide, these products are regulated as either as drugs or devices and in some countries as both. In the US, this class of products is regulated as Class III medical devices, which places specific regulatory requirements on developers of these materials under a Pre-Market Approval process, typically requiring data from prospective randomized controlled clinical studies. In 1984 pharmaceutical manufacturers became able to file an Abbreviated New Drug Application for approval of a generic drug, thus establishing standards for demonstrating equivalence to an existing chemical entity. Recently, the first biosimilar, or 'generic biologic', was approved. Biosimilars are biological products that are approved by the FDA because they are 'highly similar' to a reference product, and have been shown to have no clinically meaningful differences from the reference product. For devices, Class II medical devices have a pathway for declaring equivalence to an existing product by filing a 510 k application for FDA clearance. However, until recently no equivalent regulatory pathway was available to Class III devices. In this paper, we consider the critical mechanical performance parameters for intra-articular hyaluronic products to demonstrate indistinguishable characteristics. Analogous to the aforementioned pathways that allow for a demonstration of equivalence, we examine these parameters for an existing, marketed device and compare molecular weight and rheological properties of multiple batches of a similar product. We propose that this establishes a scientific rationale for establishing Class III medical device equivalence.

  5. PERFORMANCE TESTING OF AIR CLEANING PRODUCTS

    EPA Science Inventory

    The paper discuses the application of the Environmental Technology Verification (ETV) Program for products that clean ventilation air to the problem of protecting buildings from chemical and biological attack. This program is funded by the U.S. Environmental Protection Agency und...

  6. Pressure coefficient evaluation on the surface of the SONDA III model tested in the TTP Pilot Transonic Wind Tunnel

    NASA Astrophysics Data System (ADS)

    Reis, M. L. C. C.; Falcao Filho, J. B. P.; Basso, E.; Caldas, V. R.

    2015-02-01

    A test campaign of the Brazilian sounding rocket Sonda III was carried out at the Pilot Transonic Wind Tunnel, TTP. The aim of the campaign was to investigate aerodynamic phenomena taking place at the connection region of the first and second stages. Shock and expansion waves are expected at this location causing high gradients in airflow properties around the vehicle. Pressure taps located on the surface of a Sonda III half model measure local static pressures. Other measured parameters were freestream static and total pressures of the airflow. Estimated parameters were pressure coefficients and Mach numbers. Uncertainties associated with the estimated parameters were calculated by employing the Law of Propagation of Uncertainty and the Monte Carlo method. It was found that both uncertainty evaluation methods resulted in similar values. A Computational Fluid Dynamics simulation code was elaborated to help understand the changes in the flow field properties caused by the disturbances.

  7. Product acceptance environmental and destructive testing for reliability.

    SciTech Connect

    Dvorack, Michael A.; Kerschen, Thomas J.; Collins, Elmer W.

    2007-08-01

    To determine whether a component is meeting its reliability requirement during production, acceptance sampling is employed in which selected units coming off the production line are subjected to additional environmental and/or destructive tests that are within the normal environment space to which the component is expected to be exposed throughout its life in the Stockpile. This report describes what these tests are and how they are scored for reliability purposes. The roles of screens, Engineering Use Only tests, and next assembly product acceptance testing are also discussed, along with both the advantages and disadvantages of environmental and destructive testing.

  8. Production of fine structures in type III solar radio bursts due to turbulent density profiles

    SciTech Connect

    Loi, Shyeh Tjing; Cairns, Iver H.; Li, Bo

    2014-07-20

    Magnetic reconnection events in the corona release energetic electron beams along open field lines, and the beams generate radio emission at multiples of the electron plasma frequency f{sub p} to produce type III solar radio bursts. Type III bursts often exhibit irregularities in the form of flux modulations with frequency and/or local temporal advances and delays, and a type IIIb burst represents the extreme case where a type III burst is fragmented into a chain of narrowband features called striae. Remote and in situ spacecraft measurements have shown that density turbulence is ubiquitous in the corona and solar wind, and often exhibits a Kolmogorov power spectrum. In this work, we numerically investigate the effects of one-dimensional macroscopic density turbulence (along the beam direction) on the behavior of type III bursts, and find that this turbulence produces stria-like fine structures in the dynamic spectra of both f{sub p} and 2 f{sub p} radiation. Spectral and temporal fine structures in the predicted type III emission are produced by variations in the scattering path lengths and group speeds of radio emission, and in the locations and sizes of emitting volumes. Moderate turbulence levels yield flux enhancements with much broader half-power bandwidths in f{sub p} than 2 f{sub p} emission, possibly explaining the often observed type IIIb-III harmonic pairs as being where intensifications in 2 f{sub p} radiation are not resolved observationally. Larger turbulence levels producing trough-peak regions in the plasma density profile may lead to broader, resolvable intensifications in 2 f{sub p} radiation, which may account for the type IIIb-IIIb pairs that are sometimes observed.

  9. Production of Fine Structures in Type III Solar Radio Bursts Due to Turbulent Density Profiles

    NASA Astrophysics Data System (ADS)

    Loi, Shyeh Tjing; Cairns, Iver H.; Li, Bo

    2014-07-01

    Magnetic reconnection events in the corona release energetic electron beams along open field lines, and the beams generate radio emission at multiples of the electron plasma frequency fp to produce type III solar radio bursts. Type III bursts often exhibit irregularities in the form of flux modulations with frequency and/or local temporal advances and delays, and a type IIIb burst represents the extreme case where a type III burst is fragmented into a chain of narrowband features called striae. Remote and in situ spacecraft measurements have shown that density turbulence is ubiquitous in the corona and solar wind, and often exhibits a Kolmogorov power spectrum. In this work, we numerically investigate the effects of one-dimensional macroscopic density turbulence (along the beam direction) on the behavior of type III bursts, and find that this turbulence produces stria-like fine structures in the dynamic spectra of both fp and 2 fp radiation. Spectral and temporal fine structures in the predicted type III emission are produced by variations in the scattering path lengths and group speeds of radio emission, and in the locations and sizes of emitting volumes. Moderate turbulence levels yield flux enhancements with much broader half-power bandwidths in fp than 2 fp emission, possibly explaining the often observed type IIIb-III harmonic pairs as being where intensifications in 2 fp radiation are not resolved observationally. Larger turbulence levels producing trough-peak regions in the plasma density profile may lead to broader, resolvable intensifications in 2 fp radiation, which may account for the type IIIb-IIIb pairs that are sometimes observed.

  10. 46 CFR 160.174-25 - Production testing.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Thermal Protective Aids § 160.174-25 Production testing. (a) Thermal protective aid production testing is conducted under the procedures in this section and subpart 159.007 of this chapter. (b) One out of every 100 thermal protective aids produced must be given...

  11. 46 CFR 160.174-25 - Production testing.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Thermal Protective Aids § 160.174-25 Production testing. (a) Thermal protective aid production testing is conducted under the procedures in this section and subpart 159.007 of this chapter. (b) One out of every 100 thermal protective aids produced must be given...

  12. Establishment and tests of EnOI assimilation module for WAVEWATCH III

    NASA Astrophysics Data System (ADS)

    Qi, Peng; Cao, Lei

    2015-09-01

    In this paper, we propose a parallel data assimilation module based on ensemble optimal interpolation (EnOI). We embedded the method into the full-spectral third-generation wind-wave model, WAVEWATCH III Version 3.14, producing a wave data assimilation system. We present our preliminary experiments assimilating altimeter significant wave heights (SWH) using the EnOI-based wave assimilation system. Waters north of 15°S in the Indian Ocean and South China Sea were chosen as the target computational domain, which was two-way nested into the global implementation of the WAVEWATCH III. The wave model was forced by six-hourly ocean surface wind velocities from the cross-calibrated multi-platform wind vector dataset. The assimilation used along-track SWH data from the Jason-2 altimeter. We evaluated the effect of the assimilation on the analyses and hindcasts, and found that our technique was effective. Although there was a considerable mean bias in the control SWHs, a month-long consecutive assimilation reduced the bias by approximately 84% and the root mean-square error (RMSE) by approximately 65%. Improvements in the SWH RMSE for both the analysis and hindcast periods were more significant in July than January, because of the monsoon climate. The improvement in model skill persisted for up to 48 h in July. Furthermore, the SWH data assimilation had the greatest impact in areas and seasons where and when the sea-states were dominated by swells.

  13. CTBTO Contractor Laboratory Test Sample Production Report

    SciTech Connect

    Bob Hague; Tracy Houghton; Nick Mann; Matt Watrous

    2013-08-01

    In October 2012 scientists from both Idaho National Laboratory (INL) and the CTBTO contact laboratory at Seibersdorf, Austria designed a system and capability test to determine if the INL could produce and deliver a short lived radio xenon standard in time for the standard to be measured at the CTBTO contact laboratory at Seibersdorf, Austria. The test included sample standard transportation duration and potential country entrance delays at customs. On October 23, 2012 scientists at the Idaho National Laboratory (INL) prepared and shipped a Seibersdorf contract laboratory supplied cylinder. The canister contained 1.0 scc of gas that consisted of 70% xenon and 30% nitrogen by volume. The t0 was October 24, 2012, 1200 ZULU. The xenon content was 0.70 +/ 0.01 scc at 0 degrees C. The 133mXe content was 4200 +/ 155 dpm per scc of stable xenon on t0 (1 sigma uncertainty). The 133Xe content was 19000 +/ 800 dpm per scc of stable xenon on t0 (1 sigma uncertainty).

  14. 46 CFR 57.06-2 - Production test plate interval of testing.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... WELDING AND BRAZING Production Tests § 57.06-2 Production test plate interval of testing. (a) At least one... follows: (1) When the extent of welding on a single vessel exceeds 50 lineal feet of either or both... joint. (2) When the extent of welding on vessels welded in succession exceeds 50 lineal feet of...

  15. 46 CFR 57.06-2 - Production test plate interval of testing.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... WELDING AND BRAZING Production Tests § 57.06-2 Production test plate interval of testing. (a) At least one... follows: (1) When the extent of welding on a single vessel exceeds 50 lineal feet of either or both... joint. (2) When the extent of welding on vessels welded in succession exceeds 50 lineal feet of...

  16. 46 CFR 57.06-2 - Production test plate interval of testing.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... WELDING AND BRAZING Production Tests § 57.06-2 Production test plate interval of testing. (a) At least one... follows: (1) When the extent of welding on a single vessel exceeds 50 lineal feet of either or both... joint. (2) When the extent of welding on vessels welded in succession exceeds 50 lineal feet of...

  17. 46 CFR 57.06-2 - Production test plate interval of testing.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... WELDING AND BRAZING Production Tests § 57.06-2 Production test plate interval of testing. (a) At least one... follows: (1) When the extent of welding on a single vessel exceeds 50 lineal feet of either or both... joint. (2) When the extent of welding on vessels welded in succession exceeds 50 lineal feet of...

  18. 46 CFR 57.06-2 - Production test plate interval of testing.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... WELDING AND BRAZING Production Tests § 57.06-2 Production test plate interval of testing. (a) At least one... follows: (1) When the extent of welding on a single vessel exceeds 50 lineal feet of either or both... joint. (2) When the extent of welding on vessels welded in succession exceeds 50 lineal feet of...

  19. A Descriptive Analysis of Test Session Observation Checklist Ratings from the Woodcock Johnson III Standardization Sample

    ERIC Educational Resources Information Center

    Frisby, Craig L.; Osterlind, Steven J.

    2006-01-01

    Modern scale construction techniques have been used to develop scales measuring examiner ratings of examinees' test session behavior (TSB) on Wechsler and Stanford-Binet intelligence tests. This study analyzes data from the Test Session Observation Checklist (TSOC), a measure developed by post hoc rational analysis, from a portion of the Woodcock…

  20. 46 CFR 163.003-27 - Production tests and examination.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... MATERIALS: SPECIFICATIONS AND APPROVAL CONSTRUCTION Pilot Ladder § 163.003-27 Production tests and examination. (a) General. Each ladder produced under Coast Guard approval must be tested in accordance with... Coast Guard approval number and each assembled ladder that fails testing may not be sold as Coast...

  1. 46 CFR 163.003-27 - Production tests and examination.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... MATERIALS: SPECIFICATIONS AND APPROVAL CONSTRUCTION Pilot Ladder § 163.003-27 Production tests and examination. (a) General. Each ladder produced under Coast Guard approval must be tested in accordance with... Coast Guard approval number and each assembled ladder that fails testing may not be sold as Coast...

  2. 46 CFR 160.017-27 - Production tests and examination.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... MATERIALS: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Chain Ladder § 160.017-27 Production tests and examination. (a) General. Each ladder manufactured under Coast Guard approval must be tested in accordance... the Coast Guard approval number and each assembled ladder that fails testing may not be sold as...

  3. 46 CFR 160.017-27 - Production tests and examination.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... MATERIALS: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Chain Ladder § 160.017-27 Production tests and examination. (a) General. Each ladder manufactured under Coast Guard approval must be tested in accordance... the Coast Guard approval number and each assembled ladder that fails testing may not be sold as...

  4. 46 CFR 160.040-5 - Approval and production tests.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Rocket Type (and Equipment) § 160.040-5 Approval and production tests. (a) Approval tests. An independent... lot of rockets which fails the inspections and tests must not be represented as meeting this subpart... rockets at least once each year. The inspection must determine that the appliances and rockets are...

  5. 46 CFR 160.040-5 - Approval and production tests.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Rocket Type (and Equipment) § 160.040-5 Approval and production tests. (a) Approval tests. An independent... lot of rockets which fails the inspections and tests must not be represented as meeting this subpart... rockets at least once each year. The inspection must determine that the appliances and rockets are...

  6. 46 CFR 160.040-5 - Approval and production tests.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Rocket Type (and Equipment) § 160.040-5 Approval and production tests. (a) Approval tests. An independent... lot of rockets which fails the inspections and tests must not be represented as meeting this subpart... rockets at least once each year. The inspection must determine that the appliances and rockets are...

  7. 46 CFR 160.040-5 - Approval and production tests.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Rocket Type (and Equipment) § 160.040-5 Approval and production tests. (a) Approval tests. An independent... lot of rockets which fails the inspections and tests must not be represented as meeting this subpart... rockets at least once each year. The inspection must determine that the appliances and rockets are...

  8. 46 CFR 54.05-16 - Production toughness testing.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... stainless steel that is exempted from impact test requirements by this subchapter. In the case of stainless... set of three Charpy impact bars or two drop-weight specimens, as applicable according to the test used... production impact tests will be of weld metal and half of heat affected zone material. For the weld...

  9. 46 CFR 163.002-27 - Production tests and examination.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... MATERIALS: SPECIFICATIONS AND APPROVAL CONSTRUCTION Pilot Hoist § 163.002-27 Production tests and... laboratory. If the hoist fails the tests its defects must be corrected and retested until it passes. The... as Coast Guard approved unless it passes testing and unless each defect discovered in the...

  10. Process for forming shaped group III-V semiconductor nanocrystals, and product formed using process

    DOEpatents

    Alivisatos, A. Paul; Peng, Xiaogang; Manna, Liberato

    2001-01-01

    A process for the formation of shaped Group III-V semiconductor nanocrystals comprises contacting the semiconductor nanocrystal precursors with a liquid media comprising a binary mixture of phosphorus-containing organic surfactants capable of promoting the growth of either spherical semiconductor nanocrystals or rod-like semiconductor nanocrystals, whereby the shape of the semiconductor nanocrystals formed in said binary mixture of surfactants is controlled by adjusting the ratio of the surfactants in the binary mixture.

  11. Assessing contaminant sensitivity of endangered and threatened aquatic species: Part III. Effluent toxicity tests

    USGS Publications Warehouse

    Dwyer, F.J.; Hardesty, D.K.; Henke, C.E.; Ingersoll, C.G.; Whites, D.W.; Augspurger, T.; Canfield, T.J.; Mount, D.R.; Mayer, F.L.

    2005-01-01

    Toxicity tests using standard effluent test procedures described by the U.S. Environmental Protection Agency were conducted with Ceriodaphnia dubia, fathead minnows (Pimephales promelas), and seven threatened and endangered (listed) fish species from four families: (1) Acipenseridae: shortnose sturgeon (Acipenser brevirostrum); (2) Catostomidae; razorback sucker (Xyrauchen texanus); (3) Cyprinidae: bonytail chub (Gila elegans), Cape Fear shiner (Notropis mekistocholas) Colorado pikeminnow (Ptychocheilus lucius), and spotfin chub (Cyprinella monacha); and (4) Poecillidae: Gila topminnow (Poeciliopsis occidentalis). We conducted 7-day survival and growth studies with embryo-larval fathead minnows and analogous exposures using the listed species. Survival and reproduction were also determined with C. dubia. Tests were conducted with carbaryl, ammonia-or a simulated effluent complex mixture of carbaryl, copper, 4-nonylphenol, pentachlorophenol and permethrin at equitoxic proportions. In addition, Cape Fear shiners and spotfin chub were tested using diazinon, copper, and chlorine. Toxicity tests were also conducted with field-collected effluents from domestic or industrial facilities. Bonytail chub and razorback suckers were tested with effluents collected in Arizona whereas effluent samples collected from North Carolina were tested with Cape Fear shiner, spotfin chub, and shortnose sturgeon. The fathead minnow 7-day effluent test was often a reliable estimator of toxic effects to the listed fishes. However, in 21 % of the tests, a listed species was more sensitive than fathead minnows. More sensitive species results varied by test so that usually no species was always more or less sensitive than fathead minnows. Only the Gila topminnow was consistently less sensitive than the fathead minnow. Listed fish species were protected 96% of the time when results for both fathead minnows and C. dubia were considered, thus reinforcing the value of standard whole

  12. [Testing of medicinal products produced from pooled plasma].

    PubMed

    Unkelbach, U; Hunfeld, A; Breitner-Ruddock, S

    2014-10-01

    Medicinal products produced from human plasma fall under the administrative batch release procedure of the competent authority. In Germany, this has been carried out since 1995 by the Paul Ehrlich Institute (PEI), the responsible state control agency for blood products. Medicinal products released for the European and national market are tested for quality, efficacy and safety. Experimental testing of the final product and the starting materials, the plasma pools, as well as control of the production documentation guarantee a constantly high product safety. In the 28,000 batches tested since the beginning of the state controlled batch release testing of these blood products at the PEI, there has been no transmission of infectious viruses (HIV, HBV and HCV) to any patient. The batch release has made a contribution to the improvement of product quality. This procedure is still an important tool to ensure safety of blood products. The PEI is integrated in the batch release network of the European Directorate for the Quality of Medicines & Health Care (EDQM) in Strasbourg. Regulations and guidelines for official control authority batch release (OCABR) ensure harmonized procedures for mutual recognition of batch release on the European level. The EU certificates and German national certificates are requested and accepted in over 70 countries worldwide. Experimental testing in the EU and the requisite certificates have developed into a seal of quality for the world market. PMID:25213735

  13. Phase III Integrated Water Recovery Testing at MSFC - Closed hygiene and potable loop test results and lesson learned

    NASA Technical Reports Server (NTRS)

    Holder, Donald W., Jr.; Bagdigian, Robert M.

    1992-01-01

    A series of tests has been conducted at the NASA Marshall Space Flight Center (MSFC) to evaluate the performance of a Space Station Freedom (SSF) pre-development water recovery system. Potable, hygiene, and urine reclamation subsystems were integrated with end-use equipment items and successfully operated for a total of 35 days, including 23 days in closed-loop mode with man-in-the-loop. Although several significant subsystem physical anomalies were encountered, reclaimed potable and hygiene water routinely met current SSF water quality specifications. This paper summarizes the test objectives, system design, test activities/protocols, significant results/anomalies, and major lessons learned.

  14. Coeur d'Alene Tribal Production Facility, Volume II of III, 2002-2003 Progress Report.

    SciTech Connect

    Anders, Paul

    2003-01-01

    This appendices covers the following reports: (1) Previous ISRP Reviews (Project 199004400) Implement Fisheries Enhancement Opportunities-Coeur d'Alene Reservation; (2) Step 1 review of the hatchery master plan (Memorandum from Mark Fritsch, Fish Production Coordinator, Draft version March 10, 2000); (3) Coeur d'Alene Tribe response to ISRP comments on Project No. 199004402; includes attachment A Water Quantity Report. This is an incomplete document Analysis of Well Yield Potential for a Portion of the Coeur d'Alene Reservation near Worley, Idaho, February 2001; (4) Coeur d'Alene Tribe Fisheries Program, Rainbow Trout Feasibility Report on the Coeur d'Alene Indian Reservation prepared by Ronald L. Peters, February 2001; (5) Coeur d'Alene Tribe response letter pursuant to the questions raised in the Step 1 review of the Coeur d'Alene Tribe Trout Production Facility from Ronald L. Peters, March 27, 2001 ; includes attachments Water quantity report (this is the complete report), Appendix A Logs for Test Wells and 1999 Worley West Park Well, letters from Ralston, Appendix B Cost of Rainbow Purchase Alternative; (6) NPPC response (memorandum from Mark Fritsch, March 28, 2001); (7) Response to NPPC (letter to Frank Cassidy, Jr., Chair, from Ernest L. Stensgar, April 18, 2001); (8) Final ISRP review (ISRP 2001-4: Mountain Columbia Final Report); (9) Response to ISRP comment (letter to Mark Walker, Director of Public Affairs, from Ronald Peters, May 7, 2001); (10) Final comments to the Fish 4 committee; (11) Scope of Work/Budget FY 2001-2004; (12) Letter from City of Worley concerning water service; (13) Letter to BPA regarding status of Step 1 package; (14) Fisheries Habitat Evaluation on Tributaries of the Coeur d'Alene Indian Reservation, 1990 annual report; (15) Fisheries Habitat Evaluation on Tributaries of the Coeur d'Alene Indian Reservation, 1991 annual report; and (16) Fisheries Habitat Evaluation on Tributaries of the Coeur d'Alene Indian Reservation, 1992 annual

  15. Report of "C" Testing. Beginning Teacher Evaluation Study. Technical Note Series. Technical Note III-4.

    ERIC Educational Resources Information Center

    Cahen, Leonard S.

    The "C" testing program, which followed the "A" and "B" tests of the Beginning Teacher Evaluation Study, is summarized. A sample of 139 second grade and 123 fifth grade students completed the reading and mathematics achievement battery, as well as affective scales regarding reading, mathematics, and school. The administration procedures, test…

  16. Paths to Success, Volume III. Validating the California Chemistry Diagnostic Test for Local Use.

    ERIC Educational Resources Information Center

    Karpp, Edward R.

    The California Chemistry Diagnostic Test (CCDT) was developed by chemistry faculties at the University of California, California State University, and California Community College systems to address dissatisfaction with existing chemistry assessment instruments. The instrument was tested at 25 campuses of the 3 systems, after which Glendale…

  17. Evaluation of Sled Tests for Spacecraft Dynamic Environments using the Small Female and Large Male Hybrid III Anthropomorphic Test Devices

    NASA Technical Reports Server (NTRS)

    Wells, Jessica A.; Somers, Jeffrey T.; Newby, Nathaniel J.; Putnam, Jacob F.; Currie-Gregg, Nancy J.; Lawrence, Charles

    2016-01-01

    Anthropomorphic test devices (ATD) are widely used for military and automotive applications. These ATDs have been correlated to certain types of human injuries largely involving automotive-type energetics and directions of impact. Spacecraft dynamic events involve very different impact characteristics and, in the case of landings, require lower levels of acceptable injury risk due to the certainty of impact occurrence. This test series evaluated the small female and large male Hybrid IIII ATDs for spacecraft dynamic events.

  18. Strain Gage Loads Calibration Testing with Airbag Support for the Gulfstream III SubsoniC Research Aircraft Testbed (SCRAT)

    NASA Technical Reports Server (NTRS)

    Lokos, William; Miller, Eric; Hudson, Larry; Holguin, Andrew; Neufeld, David; Haraguchi, Ronnie

    2015-01-01

    This paper describes the design and conduct of the strain gage load calibration ground test of the SubsoniC Research Aircraft Testbed, Gulfstream III aircraft, and the subsequent data analysis and its results. The goal of this effort was to create and validate multi-gage load equations for shear force, bending moment, and torque for two wing measurement stations. For some of the testing the aircraft was supported by three air bags in order to isolate the wing structure from extraneous load inputs through the main landing gear. Thirty-two strain gage bridges were installed on the left wing. Hydraulic loads were applied to the wing lower surface through a total of 16 load zones. Some dead weight load cases were applied to the upper wing surface using shot bags. Maximum applied loads reached 54,000 pounds.

  19. Reliability of a Shuttle Run Test for Children with Cerebral Palsy Who Are Classified at Gross Motor Function Classification System Level III

    ERIC Educational Resources Information Center

    Verschuren, Olaf; Bosma, Liesbeth; Takken, Tim

    2011-01-01

    For children and adolescents with cerebral palsy (CP) classified as Gross Motor Function Classification System (GMFCS) level III there is no running-based field test available to assess their cardiorespiratory fitness. The current study investigated whether a shuttle run test can be reliably (test-retest) performed in a group of children with…

  20. Significance of Iron(II,III) Hydroxycarbonate Green Rust in Arsenic Remediation Using Zerovalent Iron in Laboratory Column Tests

    EPA Science Inventory

    We examined the corrosion products of zerovalent iron used in three column tests for removing arsenic from water under dynamic flow conditions. Each column test lasted three- to four-months using columns consisting of a 10.3-cm depth of 50 : 50 (w : w, Peerless iron : sand) in t...

  1. Development, Antibiotic Production, and Ribosome Assembly in Streptomyces venezuelae Are Impacted by RNase J and RNase III Deletion

    PubMed Central

    Jones, Stephanie E.; Leong, Vivian; Ortega, Joaquin

    2014-01-01

    RNA metabolism is a critical but frequently overlooked control element affecting virtually every cellular process in bacteria. RNA processing and degradation is mediated by a suite of ribonucleases having distinct cleavage and substrate specificity. Here, we probe the role of two ribonucleases (RNase III and RNase J) in the emerging model system Streptomyces venezuelae. We show that each enzyme makes a unique contribution to the growth and development of S. venezuelae and further affects the secondary metabolism and antibiotic production of this bacterium. We demonstrate a connection between the action of these ribonucleases and translation, with both enzymes being required for the formation of functional ribosomes. RNase III mutants in particular fail to properly process 23S rRNA, form fewer 70S ribosomes, and show reduced translational processivity. The loss of either RNase III or RNase J additionally led to the appearance of a new ribosomal species (the 100S ribosome dimer) during exponential growth and dramatically sensitized these mutants to a range of antibiotics. PMID:25266378

  2. Subsonic Ultra Green Aircraft Research: Phase II- Volume III-Truss Braced Wing Aeroelastic Test Report

    NASA Technical Reports Server (NTRS)

    Bradley, Marty K.; Allen, Timothy J.; Droney, Christopher

    2014-01-01

    This Test Report summarizes the Truss Braced Wing (TBW) Aeroelastic Test (Task 3.1) work accomplished by the Boeing Subsonic Ultra Green Aircraft Research (SUGAR) team, which includes the time period of February 2012 through June 2014. The team consisted of Boeing Research and Technology, Boeing Commercial Airplanes, Virginia Tech, and NextGen Aeronautics. The model was fabricated by NextGen Aeronautics and designed to meet dynamically scaled requirements from the sized full scale TBW FEM. The test of the dynamically scaled SUGAR TBW half model was broken up into open loop testing in December 2013 and closed loop testing from January 2014 to April 2014. Results showed the flutter mechanism to primarily be a coalescence of 2nd bending mode and 1st torsion mode around 10 Hz, as predicted by analysis. Results also showed significant change in flutter speed as angle of attack was varied. This nonlinear behavior can be explained by including preload and large displacement changes to the structural stiffness and mass matrices in the flutter analysis. Control laws derived from both test system ID and FEM19 state space models were successful in suppressing flutter. The control laws were robust and suppressed flutter for a variety of Mach, dynamic pressures, and angle of attacks investigated.

  3. Head excursion of restrained human volunteers and hybrid III dummies in steady state rollover tests.

    PubMed

    Moffatt, Edward; Hare, Barry; Hughes, Raymond; Lewis, Lance; Iiyama, Hiroshi; Curzon, Anne; Cooper, Eddie

    2003-01-01

    Seatbelts provide substantial benefits in rollover crashes, yet occupants still receive head and neck injuries from contacting the vehicle roof interior when the roof exterior strikes the ground. Prior research has evaluated rollover restraint performance utilizing anthropomorphic test devices (dummies), but little dynamic testing has been done with human volunteers to learn how they move during rollovers. In this study, the vertical excursion of the head of restrained dummies and human subjects was measured in a vehicle being rotated about its longitudinal roll axis at roll rates from 180-to-360 deg/sec and under static inversion conditions. The vehicle's restraint design was the commonly used 3-point seatbelt with continuous loop webbing and a sliding latch plate. This paper presents an analysis of the observed occupant motion and provides a comparison of dummy and human motion under similar test conditions. Thirty-five tests (eighteen static and seventeen dynamic) were completed using two different sizes of dummies and human subjects in both near and far-side roll directions. The research indicates that far-side rollovers cause the restrained test subjects to have greater head excursion than near-side rollovers, and that static inversion testing underestimates head excursion for far-side occupants. Human vertical head excursion of up to 200 mm was found at a roll rate of 220 deg/sec. Humans exhibit greater variability in head excursion in comparison to dummies. Transfer of seatbelt webbing through the latch plate did not correlate directly with differences in head excursion.

  4. Production and preliminary testing of multianalyte imaging sensor arrays

    SciTech Connect

    Richards, J.B.; Brown, S.B.; Milanovich, F.P.; Healey, B.G.; Chadha, S.; Walt, D.R.

    1994-11-01

    This report covers the production and preliminary testing of fiber optic sensors that contain a discrete array of analyte specific sensors on their distal ends. The development of the chemistries associated with this technology is covered elsewhere.

  5. 21 CFR 640.92 - Tests on final product.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... ADDITIONAL STANDARDS FOR HUMAN BLOOD AND BLOOD PRODUCTS Plasma Protein Fraction (Human) § 640.92 Tests on...) Heat stability. A final container sample of Plasma Protein Fraction (Human) shall remain unchanged,...

  6. 21 CFR 640.92 - Tests on final product.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... ADDITIONAL STANDARDS FOR HUMAN BLOOD AND BLOOD PRODUCTS Plasma Protein Fraction (Human) § 640.92 Tests on...) Heat stability. A final container sample of Plasma Protein Fraction (Human) shall remain unchanged,...

  7. 21 CFR 640.92 - Tests on final product.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... ADDITIONAL STANDARDS FOR HUMAN BLOOD AND BLOOD PRODUCTS Plasma Protein Fraction (Human) § 640.92 Tests on...) Heat stability. A final container sample of Plasma Protein Fraction (Human) shall remain unchanged,...

  8. 21 CFR 640.92 - Tests on final product.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... ADDITIONAL STANDARDS FOR HUMAN BLOOD AND BLOOD PRODUCTS Plasma Protein Fraction (Human) § 640.92 Tests on...) Heat stability. A final container sample of Plasma Protein Fraction (Human) shall remain unchanged,...

  9. 21 CFR 640.92 - Tests on final product.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... ADDITIONAL STANDARDS FOR HUMAN BLOOD AND BLOOD PRODUCTS Plasma Protein Fraction (Human) § 640.92 Tests on...) Heat stability. A final container sample of Plasma Protein Fraction (Human) shall remain unchanged,...

  10. INEL advanced test reactor plutonium-238 production feasibility assessment

    SciTech Connect

    Schnitzler, B.G. )

    1993-01-10

    Results of a preliminary neutronics assessment indicate the feasibility of [sup 238]Pu production in the Idaho National Engineering Laboratory Advanced Test Reactor (ATR). Based on the results of this assessment, an annual production of 11.3 kg [sup 238]Pu can be achieved in the ATR. An annual loading of 102 kg [sup 237]Np is required for the particular target configuration and irradiation scenario examined. The [sup 236]Pu contaminant level is approximately 6 parts per million at zero cooling time. The product quality is about 90% [sup 238]Pu. Neptunium feedstock requirements, [sup 238]Pu production rates, or product purity can be optimized depending on their relative importances.

  11. Application of in vitro neurotoxicity testing for regulatory purposes: Symposium III summary and research needs.

    PubMed

    Bal-Price, Anna K; Suñol, Cristina; Weiss, Dieter G; van Vliet, Erwin; Westerink, Remco H S; Costa, Lucio G

    2008-05-01

    Prediction of neurotoxic effects is a key feature in the toxicological profile of many compounds and therefore is required by regulatory testing schemes. Nowadays neurotoxicity assessment required by the OECD and EC test guidelines is based solely on in vivo testing, evaluating mainly effects on neurobehavior and neuropathology, which is expensive, time consuming and unsuitable for screening large number of chemicals. Additionally, such in vivo tests are not always sensitive enough to predict human neurotoxicity and often do not provide information that facilitates regulatory decision-making processes. Incorporation of alternative tests (in vitro testing, computational modelling, QSARs, grouping, read-across, etc.) in screening strategies would speed up the rate at which compound knowledge and mechanistic data are available and the information obtained could be used in the refinement of future in vivo studies to facilitate predictions of neurotoxicity. On 1st June 2007, the European Commission legislation concerning registration, evaluation and authorisation of chemicals (REACH) has entered into force. REACH addresses one of the key issues for chemicals in Europe, the lack of publicly available safety data sheets. It outlines a plan to test approximately 30,000 existing substances. These chemicals are currently produced in volumes greater than 1ton/year and the essential data on the human health and ecotoxicological effects are lacking. It is estimated that approximately 3.9 million test animals (including 2.6 million vertebrates) (Hartung T, Bremer S, Casati S, Coecke S, Corvi R, Fortnaer S, et al. ECVAM's response to the changing political environment for alternatives: consequences of the European Union chemicals and cosmetics policies. ATLA 2003;31:473-81) would be necessary to fulfill the requirements of REACH if the development and establishment of alternative methods is not accepted by regulatory authorities. In an effort to reduce animal use and testing

  12. [Temporal integration in diseased eyes. III. Fixation movements in visual acuity testing].

    PubMed

    Kono, M; Yamade, S

    1992-03-01

    The fixation movements which occur during visual acuity testing were observed in order to clarify the mechanism behind the critical duration in visual acuity testing, which we found in a previous study to be significantly longer in central serous retinopathy and macular edema. Photoelectric oculography (p-EOG) was used to record horizontal eye movement in this study. In normal eyes the frequency and amplitude of the microsaccades were smaller while the acuity target was shown than when it was not shown. This phenomenon was also observed in eyes with macular edema. These results suggest that microsaccades play no positive role in the reading of visual acuity targets, and that they bear little relation to the phenomenon of critical duration in visual acuity testing. PMID:1580224

  13. Product evaluation of in situ vitrification engineering, Test 4

    SciTech Connect

    Loehr, C.A.; Weidner, J.R.; Bates, S.O.

    1991-09-01

    This report is one of several that evaluates the In Situ Vitrification (ISV) Engineering-Scale Test 4 (ES-4). This document describes the chemical and physical composition, microstructure, and leaching characteristics of ES-4 product samples; these data provide insight into the expected performance of a vitrified product in an ISV buried waste application similar to that studied in ES-4.

  14. Bubble-Good Data: Product Testing and Other Sources.

    ERIC Educational Resources Information Center

    Atwood, Virginia A.

    1985-01-01

    The goal of this mini-unit is to teach elementary students economic concepts related to consumerism and to develop problem-solving skills. Students test a product such as sugarless bubble gum and study how it is advertised. The students then make their own advertisement for the product. (RM)

  15. Head Excursion of Restrained Human Volunteers and Hybrid III Dummies in Steady State Rollover Tests

    PubMed Central

    Moffatt, Edward; Hare, Barry; Hughes, Raymond; Lewis, Lance; Iiyama, Hiroshi; Curzon, Anne; Cooper, Eddie

    2003-01-01

    Seatbelts provide substantial benefits in rollover crashes, yet occupants still receive head and neck injuries from contacting the vehicle roof interior when the roof exterior strikes the ground. Prior research has evaluated rollover restraint performance utilizing anthropomorphic test devices (dummies), but little dynamic testing has been done with human volunteers to learn how they move during rollovers. In this study, the vertical excursion of the head of restrained dummies and human subjects was measured in a vehicle being rotated about its longitudinal roll axis at roll rates from 180-to-360 deg/sec and under static inversion conditions. The vehicle’s restraint design was the commonly used 3-point seatbelt with continuous loop webbing and a sliding latch plate. This paper presents an analysis of the observed occupant motion and provides a comparison of dummy and human motion under similar test conditions. Thirty-five tests (eighteen static and seventeen dynamic) were completed using two different sizes of dummies and human subjects in both near and far-side roll directions. The research indicates that far-side rollovers cause the restrained test subjects to have greater head excursion than near-side rollovers, and that static inversion testing underestimates head excursion for far-side occupants. Human vertical head excursion of up to 200 mm was found at a roll rate of 220 deg/sec. Humans exhibit greater variability in head excursion in comparison to dummies. Transfer of seatbelt webbing through the latch plate did not correlate directly with differences in head excursion. PMID:12941241

  16. Testing and Modeling the Responses of Hybrid III Crash-Dummy Lower Extremity under High-speed Vertical Loading.

    PubMed

    Zhu, Feng; Dong, Liqiang; Jin, Xin; Jiang, Binhui; Kalra, Anil; Shen, Ming; Yang, King H

    2015-11-01

    Anthropometric test devices (ATDs), such as the Hybrid III crash-test dummy, have been used to simulate lowerextremity responses to military personnel subjected to loading conditions from anti-vehicular (AV) landmine blasts. Numerical simulations [e.g., finite element (FE) analysis] of such high-speed vertical loading on ATD parts require accurate material parameters that are dependent on strain rate. This study presents a combined experimental and computational study to calibrate the rate-dependent properties of three materials on the lower extremities of the Hybrid III dummy. The three materials are heelpad foam, foot skin, and lower-leg flesh, and each has properties that can affect simulation results of forces and moments transferred to the lower extremities. Specifically, the behavior of the heel-pad foam was directly calibrated through standard compression tests, and the properties of the foot skin and lower-leg flesh were calibrated based on an optimization procedure in which the material parameters were adjusted for best fit between the calculated force-deflection responses and least squares of the experimental data. The material models updated with strain-rate effects were then integrated into an ATD full-body FE model (FEM), which was used to simulate vertical impulsive loading responses at different speeds. Results of validations using this model demonstrated basic replication of experimentally obtained response patterns of the tibia. The bending moments matched those calculated from the experimental data 25-40% more accurately than those obtained from the original model, and axial forces were 60-90% more accurate. However, neither the original nor the modified models well captured whole-body response patterns, and further improvements are required. As a generalized approach, the optimization method presented in this paper can be applied to characterize material constants for a wide range of materials. PMID:26660755

  17. The behavior of fission products during nuclear rocket reactor tests

    SciTech Connect

    Bokor, P.C.; Kirk, W.L.; Bohl, R.J.

    1991-01-01

    The experience base regarding fission product behavior developed during the Rover program, the nuclear rocket development program of 1955--1972, will be useful in planning a renewed nuclear rocket program. During the Rover program, 20 reactors were tested at the Nuclear Rocket Development Station in Nevada. Nineteen of these discharged effluent directly into the atmosphere; the last reactor tested, a non-flight-prototypic, fuel-element-testing reactor called the Nuclear Furnace (NF-1) was connected to an effluent cleanup system that removed fission products before the hydrogen coolant (propellant) was discharged to the atmosphere. In general, we are able to increase both test duration and fuel temperature during the test series. Therefore fission product data from the later part of the program are more interesting and more applicable to future reactors. We have collected fission product retention (and release) data reported in both formal and informal publications for six of the later reactor tests; five of these were Los Alamos reactors that were firsts of a kind in configuration or operating conditions. We have also, with the cooperation of Westinghouse, included fission product data from the NRX-A6 reactor, the final member of series of developmental reactors with the same basic geometry, but with significant design and fabrication improvements as the series continued. Table 1 lists the six selected reactors and the test parameters for each.

  18. 46 CFR Appendix III to Part 150 - Testing Procedures for Determining Exceptions to the Chart

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... or chromelalumel duplex thermocouple wire into glass capilary sheaths. The common wire of each probe... probe which produces a negative pen deflection upon warming is the reference junction and is placed in a test tube of water at ambient laboratory temperature. The other probe is placed near the bottom of...

  19. 46 CFR Appendix III to Part 150 - Testing Procedures for Determining Exceptions to the Chart

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... or chromelalumel duplex thermocouple wire into glass capilary sheaths. The common wire of each probe... probe which produces a negative pen deflection upon warming is the reference junction and is placed in a test tube of water at ambient laboratory temperature. The other probe is placed near the bottom of...

  20. Evaluation of the split cantilever beam for mode III delamination testing

    NASA Technical Reports Server (NTRS)

    Martin, Roderick, H.

    1991-01-01

    A test rig for testing a thick split cantilever beam for scissoring delamination (mode 3) fracture toughness was developed. A 3-D finite element analysis was conducted on the test specimen to determine the strain energy release rate, G, distribution along the delamination front. The virtual crack closure technique was used to calculate the G components resulting from interlaminar tension, GI, interlaminar sliding shear, GII, and interlaminar tearing shear, GIII. The finite element analysis showed that at the delamination front no GI component existed, but a GII component was present in addition to a GIII component. Furthermore, near the free edges, the GII component was significantly higher than the GIII component. The GII/GIII ratio was found to increase with delamination length but was insensitive to the beam depth. The presence of GII at the delamination front was verified experimentally by examination of the failure surfaces. At the center of the beam, where the failure was in mode 3, there was significant fiber bridging. However, at the edges of the beam where the failure was in mode 3, there was no fiber bridging and mode 2 shear hackles were observed. Therefore, it was concluded that the split cantilever beam configuration does not represent a pure mode 3 test. The experimental work showed that the mode 2 fracture toughness, GIIc, must be less than the mode 3 fracture toughness, GIIIc. Therefore, a conservative approach to characterizing mode 3 delamination is to equate GIIIc to GIIc.

  1. 46 CFR Appendix III to Part 150 - Testing Procedures for Determining Exceptions to the Chart

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... reactions can be safely contained. All tests should be performed in a well-ventilated laboratory hood... other substance (B). Shake to induce mixing. If no immediate reaction occurs, retain the mixture for at least 10 minutes to check for a delayed reaction. Results—If a violent reaction occurs, such...

  2. 46 CFR Appendix III to Part 150 - Testing Procedures for Determining Exceptions to the Chart

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... reactions can be safely contained. All tests should be performed in a well-ventilated laboratory hood... other substance (B). Shake to induce mixing. If no immediate reaction occurs, retain the mixture for at least 10 minutes to check for a delayed reaction. Results—If a violent reaction occurs, such...

  3. 46 CFR Appendix III to Part 150 - Testing Procedures for Determining Exceptions to the Chart

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... reactions can be safely contained. All tests should be performed in a well-ventilated laboratory hood... other substance (B). Shake to induce mixing. If no immediate reaction occurs, retain the mixture for at least 10 minutes to check for a delayed reaction. Results—If a violent reaction occurs, such...

  4. Final Report on Phase III Testing of Monosodium Titanate Adsorption Kinetics

    SciTech Connect

    Hobbs, D.T.

    1999-09-29

    This study consisted of a statistically designed set of tests to determine the extent and rate of adsorption of strontium, plutonium, uranium, and neptunium as a function of temperature, monosodium titanate (MST) concentration, and concentrations of sodium, strontium, plutonium, uranium, and neptunium.

  5. The Tree Drawing Test: A Measurement of Cognitive Development. Symposium III B.

    ERIC Educational Resources Information Center

    Yoshikawa, Kimio; And Others

    Reported at this symposium were investigations using the projective "Tree Drawing" test in (1) a case study of the impact of natural and cultural environments on Japanese children attending elementary and junior high schools in Singapore by Kimio Yoshikawa and K. Loganathan Mutharayan; (2) a study comparing cognitive processes of normal, mentally…

  6. 49 CFR 232.211 - Class III brake tests-trainline continuity inspection.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... pressure is being restored, the operator of the train shall know that the air brakes function as intended... determined that the brakes on the rear car of the train apply and release in response to air pressure changes... train that has previously received a Class I brake test and that has not been off air for more than...

  7. 49 CFR 232.211 - Class III brake tests-trainline continuity inspection.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... pressure is being restored, the operator of the train shall know that the air brakes function as intended... determined that the brakes on the rear car of the train apply and release in response to air pressure changes... train that has previously received a Class I brake test and that has not been off air for more than...

  8. 49 CFR 232.211 - Class III brake tests-trainline continuity inspection.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... pressure is being restored, the operator of the train shall know that the air brakes function as intended... determined that the brakes on the rear car of the train apply and release in response to air pressure changes... train that has previously received a Class I brake test and that has not been off air for more than...

  9. 49 CFR 232.211 - Class III brake tests-trainline continuity inspection.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... pressure is being restored, the operator of the train shall know that the air brakes function as intended... determined that the brakes on the rear car of the train apply and release in response to air pressure changes... train that has previously received a Class I brake test and that has not been off air for more than...

  10. 49 CFR 232.211 - Class III brake tests-trainline continuity inspection.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... pressure is being restored, the operator of the train shall know that the air brakes function as intended... determined that the brakes on the rear car of the train apply and release in response to air pressure changes... train that has previously received a Class I brake test and that has not been off air for more than...

  11. Food Production Worker. Dietetic Support Personnel Achievement Test.

    ERIC Educational Resources Information Center

    Oklahoma State Dept. of Vocational and Technical Education, Stillwater.

    This guide contains a series of multiple-choice items and guidelines to assist instructors in composing criterion-referenced tests for use in the food production worker component of Oklahoma's Dietetic Support Personnel training program. Test items addressing each of the following occupational duty areas are provided: human relations; hygiene and…

  12. Word Processing for Item Banking and Test Production. Final Report.

    ERIC Educational Resources Information Center

    Boyd, Joseph L.

    This report describes the sequence of activities that took place as the Examination Division of the New Jersey Department of Civil Service introduced a word processing system for a test item bank and for production of camera-ready test copy. The equipment selection, installation and orientation procedures are discussed. Keyboard and CRT terminals,…

  13. Data summary report for fission product release test VI-5

    SciTech Connect

    Osborne, M.F.; Lorenz, R.A.; Travis, J.R.; Webster, C.S.; Collins, J.L. )

    1991-10-01

    Test VI-5, the fifth in a series of high-temperature fission product release tests in a vertical test apparatus, was conducted in a flowing mixture of hydrogen and helium. The test specimen was a 15.2-cm-long section of a fuel rod from the BR3 reactor in Belgium which had been irradiated to a burnup of {approximately}42 MWd/kg. Using a hot cell-mounted test apparatus, the fuel rod was heated in an induction furnace under simulated LWR accident conditions to two test temperatures, 2000 K for 20 min and then 2700 K for an additional 20 min. The released fission products were collected in three sequentially operated collection trains on components designed to measure fission product transport characteristics and facilitate sampling and analysis. The results from this test were compared with those obtained in previous tests in this series and with the CORSOR-M and ORNL diffusion release models for fission product release. 21 refs., 19 figs., 12 tabs.

  14. 46 CFR 54.05-16 - Production toughness testing.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... be oriented parallel to the rolling direction of the adjacent production material. The test-plate... Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING PRESSURE VESSELS... toughness test plates shall be prepared for each 50 feet of longitudinal and circumferential butt weld...

  15. 46 CFR 54.05-16 - Production toughness testing.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... be oriented parallel to the rolling direction of the adjacent production material. The test-plate... Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING PRESSURE VESSELS... toughness test plates shall be prepared for each 50 feet of longitudinal and circumferential butt weld...

  16. 46 CFR 54.05-16 - Production toughness testing.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... be oriented parallel to the rolling direction of the adjacent production material. The test-plate... Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING PRESSURE VESSELS... toughness test plates shall be prepared for each 50 feet of longitudinal and circumferential butt weld...

  17. 46 CFR 54.05-16 - Production toughness testing.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... be oriented parallel to the rolling direction of the adjacent production material. The test-plate... Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING PRESSURE VESSELS... toughness test plates shall be prepared for each 50 feet of longitudinal and circumferential butt weld...

  18. 46 CFR 160.031-5 - Approval and production tests.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... MATERIALS: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Line-Throwing Appliance, Shoulder Gun Type (and...'s quality control procedures must include the inspection of appliances during production as well as... test. The operational test must be conducted as follows: (1) Three rounds must be fired by the gun,...

  19. 46 CFR 160.031-5 - Approval and production tests.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... MATERIALS: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Line-Throwing Appliance, Shoulder Gun Type (and...'s quality control procedures must include the inspection of appliances during production as well as... test. The operational test must be conducted as follows: (1) Three rounds must be fired by the gun,...

  20. 46 CFR 160.031-5 - Approval and production tests.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... MATERIALS: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Line-Throwing Appliance, Shoulder Gun Type (and...'s quality control procedures must include the inspection of appliances during production as well as... test. The operational test must be conducted as follows: (1) Three rounds must be fired by the gun,...

  1. 46 CFR 160.031-5 - Approval and production tests.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... MATERIALS: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Line-Throwing Appliance, Shoulder Gun Type (and...'s quality control procedures must include the inspection of appliances during production as well as... test. The operational test must be conducted as follows: (1) Three rounds must be fired by the gun,...

  2. Towards a Computer-Delivered Test of Productive Grammatical Ability

    ERIC Educational Resources Information Center

    Chapelle, Carol A.; Chung, Yoo-Ree; Hegelheimer, Volker; Pendar, Nick; Xu, Jing

    2010-01-01

    This study piloted test items that will be used in a computer-delivered and scored test of productive grammatical ability in English as a second language (ESL). Findings from research on learners' development of morphosyntactic, syntactic, and functional knowledge were synthesized to create a framework of grammatical features. We outline the…

  3. 49 CFR 173.468 - Test for LSA-III material.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... conductivity of 10 micromho/cm at 20 °C (68 °F). (4) The total activity of the free volume of water must be... less than the entire contents of the package must be immersed for 7 days in water at ambient temperature. (2) The volume of water to be used in the test must be sufficient to ensure that at the end...

  4. Performance testing open source products for the TMT event service

    NASA Astrophysics Data System (ADS)

    Gillies, K.; Bhate, Yogesh

    2014-07-01

    The software system for TMT is a distributed system with many components on many computers. Each component integrates with the overall system using a set of software services. The Event Service is a publish-subscribe message system that allows the distribution of demands and other events. The performance requirements for the Event Service are demanding with a goal of over 60 thousand events/second. This service is critical to the success of the TMT software architecture; therefore, a project was started to survey the open source and commercial market for viable software products. A trade study led to the selection of five products for thorough testing using a specially constructed computer/network configuration and test suite. The best performing product was chosen as the basis of a prototype Event Service implementation. This paper describes the process and performance tests conducted by Persistent Systems that led to the selection of the product for the prototype Event Service.

  5. H2O(+) production rates of Comets Austin 1990 V and P/Halley 1986 III

    NASA Technical Reports Server (NTRS)

    Schultz, D.; Scherb, F.; Roesler, F. L.

    1993-01-01

    High-spectral-resolution scans of H2O(+) emissions from Austin 1990 V were obtained. A simple model of the ion distribution in the FOV is used to determine a lower limit phi(H2O+) to the H2O(+) ion flux away from the nucleus for each night of observations. A similar analysis is applied to previous observations of H2O(+) emissions from Comet P/Halley 1986 III. It is found that the mean ratio is phi(H2O+)/Q(H2O) is 1.2 x exp -3 for Halley (solar minimum) and 2.6 x 10 exp -3 for Austin (solar maximum).

  6. Ab initio study on microscopic properties of III-V/water interfaces for photoelectrochemical hydrogen production

    NASA Astrophysics Data System (ADS)

    Wood, Brandon; Choi, Woon Ih; Schwegler, Eric; Ogitsu, Tadashi

    2013-03-01

    Photoelectrodes made of III-V semiconductors are known to exhibit very high solar-to-hydrogen conversion efficiency (from solar energy to chemical energy as H2 bond); however, photocorrosion of the electrode in electrolyte solution remains an issue. Based on ab-initio molecular dynamics simulations, we study the structure, stability, and chemical activity of GaP/InP(001) semiconductor electrodes in contact with water. We will show how surface oxygen and hydroxyl change the electronic and chemical properties of water at the interface, leading to the formation of a strong hydrogen-bond network where fast surface hydrogen transport seems to be realized. Implications from our findings will be discussed in detail at the presentation. This work was performed under the auspices of the U.S. Department of Energy by Lawrence Livermore National Laboratory under Contract DE-AC52- 07NA27344.

  7. The "g" Factor and Cognitive Test Session Behavior: Using a Latent Variable Approach in Examining Measurement Invariance Across Age Groups on the WJ III

    ERIC Educational Resources Information Center

    Frisby, Craig L.; Wang, Ze

    2016-01-01

    Data from the standardization sample of the Woodcock-Johnson Psychoeducational Battery--Third Edition (WJ III) Cognitive standard battery and Test Session Observation Checklist items were analyzed to understand the relationship between g (general mental ability) and test session behavior (TSB; n = 5,769). Latent variable modeling methods were used…

  8. Strain Gage Loads Calibration Testing with Airbag Support for the Gulfstream III SubsoniC Research Aircraft Testbed (SCRAT)

    NASA Technical Reports Server (NTRS)

    Lokos, William A.; Miller, Eric J.; Hudson, Larry D.; Holguin, Andrew C.; Neufeld, David C.; Haraguchi, Ronnie

    2015-01-01

    This paper describes the design and conduct of the strain-gage load calibration ground test of the SubsoniC Research Aircraft Testbed, Gulfstream III aircraft, and the subsequent data analysis and results. The goal of this effort was to create and validate multi-gage load equations for shear force, bending moment, and torque for two wing measurement stations. For some of the testing the aircraft was supported by three airbags in order to isolate the wing structure from extraneous load inputs through the main landing gear. Thirty-two strain gage bridges were installed on the left wing. Hydraulic loads were applied to the wing lower surface through a total of 16 load zones. Some dead-weight load cases were applied to the upper wing surface using shot bags. Maximum applied loads reached 54,000 lb. Twenty-six load cases were applied with the aircraft resting on its landing gear, and 16 load cases were performed with the aircraft supported by the nose gear and three airbags around the center of gravity. Maximum wing tip deflection reached 17 inches. An assortment of 2, 3, 4, and 5 strain-gage load equations were derived and evaluated against independent check cases. The better load equations had root mean square errors less than 1 percent. Test techniques and lessons learned are discussed.

  9. Preconceptual design of the new production reactor circulator test facility

    SciTech Connect

    Thurston, G.

    1990-06-01

    This report presents the results of a study of a new circulator test facility for the New Production Reactor Modular High-Temperature Gas-Cooled Reactor. The report addresses the preconceptual design of a stand-alone test facility with all the required equipment to test the Main Circulator/shutoff valve and Shutdown Cooling Circulator/shutoff valve. Each type of circulator will be tested in its own full flow, full power helium test loop. Testing will cover the entire operating range of each unit. The loop will include a test vessel, in which the circulator/valve will be mounted, and external piping. The external flow piping will include a throttle valve, flowmeter, and heat exchanger. Subsystems will include helium handling, helium purification, and cooling water. A computer-based data acquisition and control system will be provided. The estimated costs for the design and construction of this facility are included. 2 refs., 15 figs.

  10. Urine drug testing of chronic pain patients. III. Normetabolites as biomarkers of synthetic opioid use.

    PubMed

    Depriest, Anne; Heltsley, Rebecca; Black, David L; Cawthon, Beverly; Robert, Tim; Moser, Frank; Caplan, Yale H; Cone, Edward J

    2010-10-01

    Opioids are important therapeutic agents available to patients with moderate to severe pain. The synthetic opioids, buprenorphine, fentanyl, meperidine, methadone, and propoxyphene have been utilized for decades as analgesics. One of the major biotransformation pathways of these drugs occurs through N-demethylation leading to the formation and excretion of normetabolites. Normetabolites generally exhibit longer half-lives than the parent drug leading to accumulation with prolonged use. As part of continuing research efforts to improve monitoring programs of chronic pain patients undergoing opioid treatment, we evaluated the prevalence and relative abundance of normetabolites of buprenorphine, fentanyl, meperidine, methadone, and propoxyphene in patients? urine specimens. Selected sets of specimens were analyzed without prior immunoassay screening by liquid chromatography-tandem mass spectrometry for buprenorphine, fentanyl, meperidine, methadone, propoxyphene, and their respective normetabolites. Limits of quantitation (LOQ) were as follows: buprenorphine, 1 ng/mL; fentanyl, 0.5 ng/mL; meperidine, 50 ng/mL; methadone, 50 ng/mL; and propoxyphene, 50 ng/mL. LOQs for normetabolites were equal to the parent drug with the exception of norbuprenorphine (2.5 ng/mL). The percentage of positive specimens that contained normetabolite (only) ranged from 8.0% for EDDP (2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine) to 53.1% for norpropoxyphene. Inclusion of the five normetabolites in the test panel produced an increase in detection rates for parent drug use as follows: buprenorphine, 10.0%; fentanyl, 42.1%; meperidine, 98.7%; methadone, 8.7%; and propoxyphene, 113.2%. The authors conclude that testing for synthetic opioid normetabolites enhances the effectiveness of monitoring programs for pain patients. PMID:21819788

  11. Phase III Advanced Anodes and Cathodes Utilized in Energy Efficient Aluminum Production Cells

    SciTech Connect

    R.A. Christini; R.K. Dawless; S.P. Ray; D.A. Weirauch, Jr.

    2001-11-05

    During Phase I of the present program, Alcoa developed a commercial cell concept that has been estimated to save 30% of the energy required for aluminum smelting. Phase ii involved the construction of a pilot facility and operation of two pilots. Phase iii of the Advanced Anodes and Cathodes Program was aimed at bench experiments to permit the resolution of certain questions to be followed by three pilot cells. All of the milestones related to materials, in particular metal purity, were attained with distinct improvements over work in previous phases of the program. NiO additions to the ceramic phase and Ag additions to the Cu metal phase of the cermet improved corrosion resistance sufficiently that the bench scale pencil anodes met the purity milestones. Some excellent metal purity results have been obtained with anodes of the following composition: Further improvements in anode material composition appear to be dependent on a better understanding of oxide solubilities in molten cryolite. For that reason, work was commissioned with an outside consultant to model the MeO - cryolite systems. That work has led to a better understanding of which oxides can be used to substitute into the NiO-Fe2O3 ceramic phase to stabilize the ferrites and reduce their solubility in molten cryolite. An extensive number of vertical plate bench electrolysis cells were run to try to find conditions where high current efficiencies could be attained. TiB2-G plates were very inconsistent and led to poor wetting and drainage. Pure TiB2 did produce good current efficiencies at small overlaps (shadowing) between the anodes and cathodes. This bench work with vertical plate anodes and cathodes reinforced the importance of good cathode wetting to attain high current efficiencies. Because of those conclusions, new wetting work was commissioned and became a major component of the research during the third year of Phase III. While significant progress was made in several areas, much work needs to be

  12. Preclinical safety testing for cell-based products using animals.

    PubMed

    McBlane, James W

    2015-09-01

    The objectives of preclinical testing include to show why there might be therapeutic benefit in patients and to provide information on the product's toxicity. For cell-based products, given even once, there may be long term exposure and this could imply, unlike for conventional drugs, that all preclinical studies may be needed prior to first human use. The duration of exposure to cells should be studied in animals to guide toxicity assessments. Distribution of cells after administration by a route resembling that intended in humans should be studied to understand potential risks. Risk of tumour formation with the product may also need to be characterised. To the extent that this information can be generated by in vitro testing, studies in animals may not be needed and limitations on the capability of preclinical data to predict human toxicity are recognised: species-specificity make some cell products act only in humans and a human cell-product might be expected to be rejected by immunocompetent animals. Does this suggest testing in immunosuppressed animals or of development of an animal-cell product supposedly similar to the human cell product? No single answer seems to fit every situation.

  13. Preclinical safety testing for cell-based products using animals.

    PubMed

    McBlane, James W

    2015-09-01

    The objectives of preclinical testing include to show why there might be therapeutic benefit in patients and to provide information on the product's toxicity. For cell-based products, given even once, there may be long term exposure and this could imply, unlike for conventional drugs, that all preclinical studies may be needed prior to first human use. The duration of exposure to cells should be studied in animals to guide toxicity assessments. Distribution of cells after administration by a route resembling that intended in humans should be studied to understand potential risks. Risk of tumour formation with the product may also need to be characterised. To the extent that this information can be generated by in vitro testing, studies in animals may not be needed and limitations on the capability of preclinical data to predict human toxicity are recognised: species-specificity make some cell products act only in humans and a human cell-product might be expected to be rejected by immunocompetent animals. Does this suggest testing in immunosuppressed animals or of development of an animal-cell product supposedly similar to the human cell product? No single answer seems to fit every situation. PMID:26026578

  14. Fission product plateout/liftoff/washoff test plan. Revision 1

    SciTech Connect

    Acharya, R.; Hanson, D.

    1988-05-01

    A test program is planned in the COMEDIE loop of the Commissariat a l`Energy Atomique (CEA), Grenoble, France, to generate integral test data for the validation of computer codes used to predict fission product transport and core corrosion in the Modular High Temperature Gas-Cooled Reactor (MHTGR). The inpile testing will be performed by the CEA under contract from the US Department of Energy (DOE); the contract will be administered by Oak Ridge National Laboratory (ORNL). The primary purpose of this test plan is to provide an overview of the proposed program in terms of the overall scope and schedule. 8 refs, 3 figs.

  15. Improved method of HIPOT testing of advanced ignition system product

    SciTech Connect

    Baker, P.C.

    1992-04-01

    A new method of high potential (HIPOT) testing of advanced ignition system (AIS) product was developed. The new incorporated using a silver-filled RTV silicone as the electrodes of the HIPOT tester instead of the preformed, semi-rigid aluminum electrodes of the current tester. Initial results indicate that the developed method was more sensitive to the testing requirements of the HIPOT test. A patent for the combination of the material used and the method of testing developed was attempted but was withdrawn following a patent search by the US Patent Office.

  16. Dual luminophor pressure-sensitive paint: III. Application to automotive model testing

    NASA Astrophysics Data System (ADS)

    Gouterman, Martin; Callis, James; Dalton, Larry; Khalil, Gamal; Mébarki, Youssef; Cooper, Kevin R.; Grenier, Michel

    2004-10-01

    Porphyrins play key roles in natural energy conversion systems, including photosynthesis and oxygen transport. Because of their chemical stability, unique optical properties and synthetic versatility, porphyrins are well suited as chemical sensors. One successful application is the use of platinum porphyrin (PtP) in pressure-sensitive paint (PSP). Oxygen in the film quenches luminescence, and oxygen pressure was initially monitored by measuring the ratio of I(wind-off)/I(wind-on). But this ratio is compromised if there is model motion and if the paint layer is inhomogeneous. Furthermore it requires careful monitoring and placement of light sources. Moreover, this method is seriously affected by temperature. The errors caused by model motion and temperature sensitivity are eliminated or greatly reduced using dual luminophor paint. This paper illustrates a successful application of a dual luminophor PSP in auto model testing. The PSP is made from an oxygen sensitive luminophor, Pt tetra(pentafluorophenyl)-porpholactone, which provides Isen, and Mg tetra(pentafluorophenyl)porphine, which provides temperature-sensitive paint (TSP) as the pressure-independent reference. The ratio PSP/TSP in the FIB polymer produced ideal PSP measurements with a very low-temperature dependence of -0.1% °C-1.

  17. DMPS-arsenic challenge test. II. Modulation of arsenic species, including monomethylarsonous acid (MMA(III)), excreted in human urine.

    PubMed

    Aposhian, H V; Zheng, B; Aposhian, M M; Le, X C; Cebrian, M E; Cullen, W; Zakharyan, R A; Ma, M; Dart, R C; Cheng, Z; Andrewes, P; Yip, L; O'Malley, G F; Maiorino, R M; Van Voorhies, W; Healy, S M; Titcomb, A

    2000-05-15

    The administration of sodium 2,3-dimercapto-1-propane sulfonate (DMPS) to humans chronically exposed to inorganic arsenic in their drinking water resulted in the increased urinary excretion of arsenic, the appearance and identification of monomethylarsonous acid (MMA(III)) in their urine, and a large decrease in the concentration and percentage of urinary dimethylarsinic acid (DMA). This is the first time that MMA(III) has been detected in the urine. In vitro biochemical experiments were then designed and performed to understand the urinary appearance of MMA(III) and decrease of DMA. The DMPS-MMA(III) complex was not active as a substrate for the MMA(III) methyltransferase. The experimental results support the hypothesis that DMPS competes with endogenous ligands for MMA(III), forming a DMPS-MMA complex that is readily excreted in the urine and points out the need for studying the biochemical toxicology of MMA(III). It should be emphasized that MMA(III) was excreted in the urine only after DMPS administration. The results of these studies raise many questions about the potential central role of MMA(III) in the toxicity of inorganic arsenic and to the potential involvement of MMA(III) in the little-understood etiology of hyperkeratosis, hyperpigmentation, and cancer that can result from chronic inorganic arsenic exposure.

  18. Capsicum--production, technology, chemistry, and quality. Part III. Chemistry of the color, aroma, and pungency stimuli.

    PubMed

    Govindarajan, V S

    1986-01-01

    The spice capsicum, the fruits of the genus Capsicum (Family Solanaceae), is a very popular food additive in many parts of the world, valued for the important sensory attributes of color, pungency, and aroma. A large number of varieties are widely cultivated and traded. The characteristic carotenoids of the bright red paprika and cayenne-type chillies, the high character impact aroma stimuli, the methoxy pyrazine of green bell capsicum, the esters of ripe tabasco and the highly potent pungency stimuli, and the capsaicinoids of African and other Asian varieties of chillies, have been of great interest to chemists and biochemists. Research workers in other disciplines such as genetics and breeding, agriculture, and technology have been interested in this spice to develop new varieties with combinations of different optimal levels of the stimuli for the sensory attributes and to maximize production of storable products for specific end uses. Physiologists have been intensely studying the action of the highly potent pungency stimuli and social psychologists the curious aspect of growing acceptance and preference for the initially unacceptable pungency sensation. In the sequential review of all these aspects of the fruit spice Capsicum, the earlier two parts covered history, botany, cultivation and primary processing, and processed products, standards, world production, and trade. In Part III, the chemistry, the compositional variations, synthesis and biosynthesis of the functional components, the carotenoids, the volatiles, and the capsaicinoids are comprehensively reviewed. PMID:3527565

  19. THE PRODUCT CONSISTENCY TEST HOW AND WHY IT WAS DEVELOPED

    SciTech Connect

    Jantzen, C; Ned Bibler, N

    2008-12-15

    The Product Consistency Test (PCT), American Society for Testing Materials (ASTM) Standard C1285, is currently used world wide for testing glass and glass-ceramic waste forms for high level waste (HLW), low level waste (LLW), and hazardous wastes. Development of the PCT was initiated in 1986 because HLW glass waste forms required extensive characterization before actual production began and required continued characterization during production ({ge}25 years). Non-radioactive startup was in 1994 and radioactive startup was in 1996. The PCT underwent extensive development from 1986-1994 and became an ASTM consensus standard in 1994. During the extensive laboratory testing and inter- and intra-laboratory round robins using non-radioactive and radioactive glasses, the PCT was shown to be very reproducible, to yield reliable results rapidly, to distinguish between glasses of different durability and homogeneity, and to easily be performed in shielded cell facilities with radioactive samples. In 1997, the scope was broadened to include hazardous and mixed (radioactive and hazardous) waste glasses. In 2002, the scope was broadened to include glass-ceramic waste forms which are currently being recommended for second generation nuclear wastes yet to be generated in the nuclear renaissance. Since the PCT has proven useful for glass-ceramics with up to 75% ceramic component and has been used to evaluate Pu ceramic waste forms, the use of this test for other ceramic/mineral waste forms such as geopolymers, hydroceramics, and fluidized bed steam reformer mineralized product is under investigation.

  20. EPHECT III: Health risk assessment of exposure to household consumer products.

    PubMed

    Trantallidi, M; Dimitroulopoulou, C; Wolkoff, P; Kephalopoulos, S; Carrer, P

    2015-12-01

    In the framework of the EU EPHECT project (Emissions, Exposure Patterns and Health Effects of Consumer Products in the EU), irritative and respiratory effects were assessed in relation to acute (30-min) and long-term (24-h) inhalation exposure to key and emerging indoor air pollutants emitted during household use of selected consumer products. A detailed Health Risk Assessment (HRA) was performed for five selected pollutants of respiratory health relevance, namely acrolein, formaldehyde, naphthalene, d-limonene and α-pinene. For each pollutant, the Critical Exposure Limit (CEL) was compared to indoor air concentrations and exposure estimates for the use of 15 selected consumer products by two population groups (housekeepers and retired people) in the four geographical regions of Europe (North, West, South, East), which were derived previously based on microenvironmental modelling. For the present HRA, health-based CELs were derived for certain compounds in case indoor air quality guidelines were not available by the World Health Organization for end-points relevant to the current study. For each pollutant, the highest indoor air concentrations in each microenvironment and exposure estimates across home microenvironments during the day were lower than the corresponding acute and long-term CELs. However, considerable contributions, especially to acute exposures, were obtained in some cases, such as formaldehyde emissions resulting from single product use of a floor cleaning agent (82% CEL), a candle (10% CEL) and an electric air freshener (17% CEL). Regarding multiple product use, the case of 30-min formaldehyde exposure reaching 34% CEL when eight product classes were used across home microenvironments, i.e. all-purpose/kitchen/floor cleaning agents, furniture/floor polish, combustible/electric air fresheners, and perfume, needs to be highlighted. Such estimated values should be evaluated with caution, as these may be attributed to the exposure scenarios

  1. EPHECT III: Health risk assessment of exposure to household consumer products.

    PubMed

    Trantallidi, M; Dimitroulopoulou, C; Wolkoff, P; Kephalopoulos, S; Carrer, P

    2015-12-01

    In the framework of the EU EPHECT project (Emissions, Exposure Patterns and Health Effects of Consumer Products in the EU), irritative and respiratory effects were assessed in relation to acute (30-min) and long-term (24-h) inhalation exposure to key and emerging indoor air pollutants emitted during household use of selected consumer products. A detailed Health Risk Assessment (HRA) was performed for five selected pollutants of respiratory health relevance, namely acrolein, formaldehyde, naphthalene, d-limonene and α-pinene. For each pollutant, the Critical Exposure Limit (CEL) was compared to indoor air concentrations and exposure estimates for the use of 15 selected consumer products by two population groups (housekeepers and retired people) in the four geographical regions of Europe (North, West, South, East), which were derived previously based on microenvironmental modelling. For the present HRA, health-based CELs were derived for certain compounds in case indoor air quality guidelines were not available by the World Health Organization for end-points relevant to the current study. For each pollutant, the highest indoor air concentrations in each microenvironment and exposure estimates across home microenvironments during the day were lower than the corresponding acute and long-term CELs. However, considerable contributions, especially to acute exposures, were obtained in some cases, such as formaldehyde emissions resulting from single product use of a floor cleaning agent (82% CEL), a candle (10% CEL) and an electric air freshener (17% CEL). Regarding multiple product use, the case of 30-min formaldehyde exposure reaching 34% CEL when eight product classes were used across home microenvironments, i.e. all-purpose/kitchen/floor cleaning agents, furniture/floor polish, combustible/electric air fresheners, and perfume, needs to be highlighted. Such estimated values should be evaluated with caution, as these may be attributed to the exposure scenarios

  2. Applicability of bacterial endotoxins test to various blood products by the use of endotoxin-specific lysates.

    PubMed

    Ochiai, Masaki; Yamamoto, Akihiko; Naito, Seishiro; Maeyama, Jun-Ichi; Masumi, Atsuko; Hamaguchi, Isao; Horiuchi, Yoshinobu; Yamaguchi, Kazunari

    2010-11-01

    Endotoxin contamination is a serious threat to the safety of parenteral drugs, and the rabbit pyrogen test has played a crucial role in controlling this contamination. Although the highly sensitive endotoxin test has replaced the pyrogen test for various pharmaceuticals, the pyrogen test is still implemented as the control test for most blood products in Japan. We examined the applicability of the endotoxin test to blood products for reliable detection and quantification of endotoxin. Nineteen types of blood products were tested for interfering factors based on spike/recovery of endotoxin by using 2 types of endotoxin-specific lysate reagents for photometric techniques. Interfering effects on the endotoxin test by the products could be eliminated by diluting from 1/2 to 1/16, with the exception of antithrombin III. However, conventional lysate reagents that also react with non-pyrogenic substances, such as (1-3)-β-D-glucan, produced results that were not relevant to endotoxin content or pyrogenicity. Our results showed that the endotoxin test would be applicable to most blood products if used with appropriate endotoxin-specific lysate reagents.

  3. Carbohydrate crops as a renewable resource for fuels production. Volume III. Juice preservation

    SciTech Connect

    Fink, D.J.; Allen, B.R.; Litchfield, J.H.; Lipinsky, E.S.

    1980-01-29

    The objective of this study was to evaluate a process to preserve sugar crop juices. The process is energy conserving in that concentrated sugar solutions are produced with little evaporation of water. A preliminary investigation was conducted of polysaccharide hydrolysis as a means for preserving mixed sugar solutions obtained from crops such as sweet sorghum. Four subtasks have been addressed during this report period: I. Concentration of Pure Sugar Solutions by Hydrolysis of Purified Starch; II. Concentration of Genuine Sugar Crop Juice by Hydrolysis of Purified Starch; III. Concentration of Pure Sugar Solutions by Hydrolysis of Genuine Biomass Starch; and IV. Concentration of Pure Sugar Solutions by Hydrolysis of Cellulosic Materials. The results obtained from the experiments conducted in Subtasks I and II included the following: (1) Concentrated sucrose-glucose-fructose solutions (greater than 50 percent) can be prepared from simulated or actual sweet sorghum juice using enzymatic thinning and saccharification of pure starch-sugar solution mixtures. (2) Enzymatic saccharification of corn meal and cracked wheat in simulated sorghum juice was also demonstrated. (3) Concentration of sugar solutions also can be accomplished by saccharification of cellulosic materials. In our experiments, inhibition of the cellobiase component of the cellulase preparation was observed. The hydrolysis studies were directed to the demonstration of the feasibility of one approach to the preparation of concentrated, microbiologically stable sugar syrups starting with sweet sorghum juice. Future work on Subtask V of this program will continue the investigations already underway and will consider other approaches to the stabilization of juices. Subtask VI of this program will consider the process economics of the Subtask I to IV approaches, or combinations of two or more methods, that are considered to be most feasible for juice preservation.

  4. Informativeness Improvement of Hardness Test Methods for Metal Product Assessment

    NASA Astrophysics Data System (ADS)

    Osipov, S.; Podshivalov, I.; Osipov, O.; Zhantybaev, A.

    2016-06-01

    The paper presents a combination of theoretical suggestions, results, and observations allowing to improve the informativeness of hardness testing process in solving problems of metal product assessment while in operation. The hardness value of metal surface obtained by a single measurement is considered to be random. Various measures of location and scattering of the random variable were experimentally estimated for a number of test samples using the correlation analysis, and their close interaction was studied. It was stated that in metal assessment, the main informative characteristics of hardness testing process are its average value and mean-square deviation for measures of location and scattering, respectively.

  5. 46 CFR 160.023-4 - Approval and production tests.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 6 2010-10-01 2010-10-01 false Approval and production tests. 160.023-4 Section 160.023-4 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Hand Combination Flare and Smoke...

  6. 46 CFR 160.023-4 - Approval and production tests.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 6 2011-10-01 2011-10-01 false Approval and production tests. 160.023-4 Section 160.023-4 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Hand Combination Flare and Smoke...

  7. 46 CFR 160.023-4 - Approval and production tests.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 6 2014-10-01 2014-10-01 false Approval and production tests. 160.023-4 Section 160.023-4 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Hand Combination Flare and Smoke...

  8. 46 CFR 160.023-4 - Approval and production tests.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 6 2013-10-01 2013-10-01 false Approval and production tests. 160.023-4 Section 160.023-4 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Hand Combination Flare and Smoke...

  9. 46 CFR 160.023-4 - Approval and production tests.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 6 2012-10-01 2012-10-01 false Approval and production tests. 160.023-4 Section 160.023-4 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Hand Combination Flare and Smoke...

  10. 46 CFR 160.036-4 - Approval and production tests.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 6 2013-10-01 2013-10-01 false Approval and production tests. 160.036-4 Section 160.036-4 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Hand-Held Rocket-Propelled Parachute Red...

  11. 46 CFR 160.036-4 - Approval and production tests.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 6 2014-10-01 2014-10-01 false Approval and production tests. 160.036-4 Section 160.036-4 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Hand-Held Rocket-Propelled Parachute Red...

  12. 46 CFR 160.036-4 - Approval and production tests.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 6 2012-10-01 2012-10-01 false Approval and production tests. 160.036-4 Section 160.036-4 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Hand-Held Rocket-Propelled Parachute Red...

  13. 46 CFR 160.036-4 - Approval and production tests.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 6 2010-10-01 2010-10-01 false Approval and production tests. 160.036-4 Section 160.036-4 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Hand-Held Rocket-Propelled Parachute Red...

  14. 46 CFR 160.036-4 - Approval and production tests.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 6 2011-10-01 2011-10-01 false Approval and production tests. 160.036-4 Section 160.036-4 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Hand-Held Rocket-Propelled Parachute Red...

  15. 49 CFR 229.313 - Product testing results and records.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 4 2014-10-01 2014-10-01 false Product testing results and records. 229.313 Section 229.313 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD LOCOMOTIVE SAFETY STANDARDS Locomotive Electronics §...

  16. 49 CFR 229.313 - Product testing results and records.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 4 2012-10-01 2012-10-01 false Product testing results and records. 229.313 Section 229.313 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD LOCOMOTIVE SAFETY STANDARDS Locomotive Electronics §...

  17. 49 CFR 229.313 - Product testing results and records.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 4 2013-10-01 2013-10-01 false Product testing results and records. 229.313 Section 229.313 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD LOCOMOTIVE SAFETY STANDARDS Locomotive Electronics §...

  18. 49 CFR 178.33b-8 - Production tests.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 3 2011-10-01 2011-10-01 false Production tests. 178.33b-8 Section 178.33b-8 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) SPECIFICATIONS FOR PACKAGINGS Specifications for...

  19. 49 CFR 178.33b-8 - Production tests.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 3 2012-10-01 2012-10-01 false Production tests. 178.33b-8 Section 178.33b-8 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) SPECIFICATIONS FOR PACKAGINGS Specifications for...

  20. 49 CFR 178.33b-8 - Production tests.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 3 2014-10-01 2014-10-01 false Production tests. 178.33b-8 Section 178.33b-8 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) SPECIFICATIONS FOR PACKAGINGS Specifications for...

  1. 46 CFR 161.012-13 - Production tests and inspections.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... MATERIALS: SPECIFICATIONS AND APPROVAL ELECTRICAL EQUIPMENT Personal Flotation Device Lights § 161.012-13 Production tests and inspections. (a) The manufacturer of approved lights must randomly select a sample of ten lights from each lot of lights produced. Each lot must not exceed 1,000 lights. At least nine...

  2. EFFECTS OF ENVIRONMENTAL CHEMICALS ON FETAL TESTES TESTOSTERONE PRODUCTION

    EPA Science Inventory

    Effects of Environmental Chemicals on Fetal Testes Testosterone Production

    Lambright, CS , Wilson, VS , Furr, J, Wolf, CJ, Noriega, N, Gray, LE, Jr.
    US EPA, ORD/NHEERL/RTD, RTP, NC

    Exposure of pregnant rodents to certain environmental chemicals during criti...

  3. 46 CFR 57.01-1 - Qualifications and production tests.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ....01-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING WELDING AND... regulations in this part shall apply to the qualification of welding procedures, welders, and brazers, and to production tests for all types of manual and machine arc and gas welding and brazing processes. (b)...

  4. 46 CFR 57.01-1 - Qualifications and production tests.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ....01-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING WELDING AND... regulations in this part shall apply to the qualification of welding procedures, welders, and brazers, and to production tests for all types of manual and machine arc and gas welding and brazing processes. (b)...

  5. 46 CFR 57.01-1 - Qualifications and production tests.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ....01-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING WELDING AND... regulations in this part shall apply to the qualification of welding procedures, welders, and brazers, and to production tests for all types of manual and machine arc and gas welding and brazing processes. (b)...

  6. 46 CFR 57.01-1 - Qualifications and production tests.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ....01-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING WELDING AND... regulations in this part shall apply to the qualification of welding procedures, welders, and brazers, and to production tests for all types of manual and machine arc and gas welding and brazing processes. (b)...

  7. 46 CFR 57.01-1 - Qualifications and production tests.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ....01-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING WELDING AND... regulations in this part shall apply to the qualification of welding procedures, welders, and brazers, and to production tests for all types of manual and machine arc and gas welding and brazing processes. (b)...

  8. 46 CFR 160.028-4 - Approval and production tests.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 6 2013-10-01 2013-10-01 false Approval and production tests. 160.028-4 Section 160.028-4 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Signal Pistols for Red Flare Distress...

  9. 46 CFR 160.066-15 - Production testing.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 6 2011-10-01 2011-10-01 false Production testing. 160.066-15 Section 160.066-15 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Distress Signal for Boats, Red Aerial Pyrotechnic Flare §...

  10. 46 CFR 160.066-15 - Production testing.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 6 2012-10-01 2012-10-01 false Production testing. 160.066-15 Section 160.066-15 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Distress Signal for Boats, Red Aerial Pyrotechnic Flare §...

  11. 46 CFR 160.066-15 - Production testing.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 6 2014-10-01 2014-10-01 false Production testing. 160.066-15 Section 160.066-15 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Distress Signal for Boats, Red Aerial Pyrotechnic Flare §...

  12. 46 CFR 160.028-4 - Approval and production tests.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 6 2012-10-01 2012-10-01 false Approval and production tests. 160.028-4 Section 160.028-4 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Signal Pistols for Red Flare Distress...

  13. 46 CFR 160.028-4 - Approval and production tests.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 6 2011-10-01 2011-10-01 false Approval and production tests. 160.028-4 Section 160.028-4 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Signal Pistols for Red Flare Distress...

  14. 46 CFR 160.066-15 - Production testing.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 6 2013-10-01 2013-10-01 false Production testing. 160.066-15 Section 160.066-15 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Distress Signal for Boats, Red Aerial Pyrotechnic Flare §...

  15. 46 CFR 160.028-4 - Approval and production tests.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 6 2014-10-01 2014-10-01 false Approval and production tests. 160.028-4 Section 160.028-4 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Signal Pistols for Red Flare Distress...

  16. 46 CFR 160.066-15 - Production testing.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 6 2010-10-01 2010-10-01 false Production testing. 160.066-15 Section 160.066-15 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Distress Signal for Boats, Red Aerial Pyrotechnic Flare §...

  17. Mechanistic determination of fission product releases for a Mark III BWR plant

    SciTech Connect

    Ludewig, H.; Yu, W.S.; Jaung, R.; Pratt, W.T.

    1986-01-01

    During the review of the GESSAR-II PRA by the Nuclear Regulatory Commission (NRC) and their contractors at Brookhaven National Laboratory (BNL) it was necessary to reanalyze potential fission product releases to the environment for several core meltdown accident sequences. The reanalysis was performed at BNL in two stages. The first stage was carried out prior to detailed mechanistic models were available at BNL and consisted of a sensitivity analysis using the MARCH and CORRAL computer codes. The effects of uncertainties in primary system retention, suppression pool scrubbing and core/concrete interactions on fission product release were handled by varying inputs to the MARCH/CORRAL codes. In this paper we outline the second stage of fission product release calculations, which was based on a system of codes developed under sponsorship of the Accident Source Term Program Office (ASTPO), USNRC. A comparison will be made between the range of source terms calculated by the first approach and the point estimate calculations provided by the more mechanistic codes. 8 refs., 2 tabs.

  18. Studies on the livestock of southern Darfur, Sudan. III. Production traits in sheep.

    PubMed

    Wilson, R T

    1976-05-01

    The results of an intensive 15 months' study of 10 flocks of indigenous sheep are recorded. Lambing rates approach 1.5 lambs per ewe per year, but a death rate of 23 per cent and an offtake of 27 per cent, means that flock numbers are probably slightly declining. Twins account for 14 per cent of all births but the death rate of twin lambs is almost twice that of single lambs up to 6 months of age. Increased productivity is therefore more likely to be achieved by improving the survival and growth rates of single lambs than by selection for twinning. The weighted average rate of lightweight gain for all surviving lambs is 82 g per day up to 1 year of age, and is better than that recorded for any other indigenous African sheep. Meat production per kg of breeding female, at 0.253 kg up to 6 months of age of the young, is almost six times the production of cattle under the same management and environmental conditions, but is inferior to that of goats.

  19. Idaho Habitat and Natural Production Monitoring Part III, 1993 Annual Report.

    SciTech Connect

    Schrader, W.C.; Petrosky, Charles E. (Idaho Department of Fish and Game, Fisheries Research Section, Boise, ID

    1994-03-01

    Effective management of wild anadromous fisheries is partly dependent on defining relationships between escapement and production. These productivity relationships (or reproduction curves) depend on the nature of density-dependent mechanisms that control the population. Inherent is developing any relationship is specifying the fish population of interest and what is meant by escapement and production by that population. This report is a summary of sampling programs at all existing and proposed anadromous fish weirs in Idaho as of fall 1992. Only permanent or semi-permanent structures where long-term data could be collected are included. The summary is stratified by class of fish and by cell or drainage using the same classifications as the Idaho Anadromous Fish Management Plan. Included in the summary are escapement objectives above the existing and proposed weirs. Recommendations based on this summary were developed to provide coverage for all classes and most major drainages, yet minimize cost and duplication of efforts. this was a usefull approach as some chinook salmon weirs were identified that could be modified to monitor steelhead trout.

  20. Chemical test for mammalian feces in grain products: collaborative study.

    PubMed

    Gerber, H R

    1989-01-01

    A collaborative study was conducted to validate the use of the AOAC alkaline phosphatase method for mammalian feces in corn meal, 44.B01-44.B06, for 7 additional products: brown rice cream, oat bran, grits, semolina, pasta flour, farina, and barley plus (a mixture of barley, oat bran, and brown rice). The proposed method determines the presence of alkaline phosphatase, an enzyme contained in mammalian feces, by using phenolphthalein diphosphate as the enzyme substrate in a test agar medium. Fecal matter is separated from the grain products by specific gravity differences in 1% test agar. As the product is distributed on liquid test agar, fecal fragments float while the grain products sink. The alkaline phosphatase cleaves phosphate radicals from phenolphthalein diphosphate, generating free phenolphthalein, which produces a pink to red-purple color around the fecal particles in the previously colorless medium. Collaborators' recovery averages ranged from 21.7 particles (72.3%) for oat bran to 25.3 particles (84.3%) for semolina at the 30 particle spike level. Overall average background was 0.4 positive reactions per food type. The collaborators reported that the method was quick, simple, and easy to use. The method has been approved interim official first action for all 7 grain products. PMID:2808238

  1. Kinematic Comparison of Pediatric Human Volunteers and the Hybrid III 6-Year-Old Anthropomorphic Test Device

    PubMed Central

    Seacrist, Thomas; Balasubramanian, Sriram; García-España, J. Felipe; Maltese, Matthew R.; Arbogast, Kristy B.; Lopez-Valdes, Francisco J.; Kent, Richard W.; Tanji, Hiromasa; Higuchi, Kazuo

    2010-01-01

    The Hybrid III 6-year-old ATD has been benchmarked against adult-scaled component level tests but the lack of biomechanical data hinders the effectiveness of the procedures used to scale the adult data to the child. Whole body kinematic validation of the pediatric ATD through limited comparison to post mortem human subjects (PMHS) of similar age and size has revealed key differences attributed to the rigidity of the thoracic spine. As restraint systems continue to advance, they may become more effective at limiting peak loads applied to occupants, leading to lower impact environments for which the biofidelity of the ATD is not well established. Consequently, there is a growing need to further enhance the assessment of the pediatric ATD by evaluating its biofidelity at lower crash speeds. To this end, this study compared the kinematic response of the Hybrid III 6 year old ATD against size-matched male pediatric volunteers (PVs) (6–9 yrs) in low-speed frontal sled tests. A 3-D near-infrared target tracking system quantified the position of markers at seven locations on the ATD and PVs (head top, opisthocranion, nasion, external auditory meatus, C4, T1, and pelvis). Angular velocity of the head, seat belt forces, and reaction forces on the seat pan and foot rest were also measured. The ATD exhibited significantly greater shoulder and lap belt, foot rest, and seat pan normal reaction loads compared to the PVs. Contrarily, PVs exhibited significantly greater seat pan shear. The ATD experienced significantly greater head angular velocity (11.4 ± 1.7 rad/s vs. 8.1 ± 1.4 rad/s), resulting in a quicker time to maximum head rotation (280.4 ± 2.5 ms vs 334.2 ± 21.7 ms). The ATD exhibited significantly less forward excursions of the nasion (171.7 ± 7.8 mm vs. 199.5 ± 12.3 mm), external auditory meatus (194.5 ± 11.8 mm vs. 205.7 ± 10.3 mm), C4 (127.0 ± 5.2 mm vs. 183.3 ± 12.8 mm) and T1 (111.1 ± 6.5 mm vs. 153.8 ± 10.5 mm) compared to the PVs. These analyses

  2. Generic development of topical dermatologic products: formulation development, process development, and testing of topical dermatologic products.

    PubMed

    Chang, Rong-Kun; Raw, Andre; Lionberger, Robert; Yu, Lawrence

    2013-01-01

    This review presents considerations which can be employed during the development of a semi-solid topical generic product. This includes a discussion on the implementation of quality by design concepts during development to ensure the generic drug product has similar desired quality attributes to the reference-listed drug (RLD) and ensure batch to batch consistency through commercial production. This encompasses the concept of reverse-engineering to copy the RLD as a strategy during product development to ensure qualitative (Q1) and quantitative (Q2) formulation similarity, as well as similarity in formulation microstructure (Q3). The concept of utilizing in vitro skin permeation studies as a tool to justify formulation differences between the test generic product and the RLD to ensure a successful pharmacodynamic or clinical endpoint bioequivalence study is discussed. The review concludes with a discussion on drug product evaluation and quality tests as well as in vivo bioequivalence studies.

  3. Coeur d'Alene Tribal Production Facility, Volume I of III, 2002-2003 Progress Report.

    SciTech Connect

    Anders, Paul

    2003-01-01

    In fulfillment of the NWPPC's 3-Step Process for the implementation of new hatcheries in the Columbia Basin, this Step 1 submission package to the Council includes four items: (1) Cover letter from the Coeur d'Alene Tribe, Interdisciplinary Team Chair, and the USFWS; (2) References to key information (Attachments 1-4); (3) The updated Master Plan for the Tribe's native cutthroat restoration project; and (4) Appendices. In support of the Master Plan submitted by the Coeur d'Alene Tribe the reference chart (Item 2) was developed to allow reviewers to quickly access information necessary for accurate peer review. The Northwest Power Planning Council identified pertinent issues to be addressed in the master planning process for new artificial production facilities. References to this key information are provided in three attachments: (1) NWPPC Program language regarding the Master Planning Process, (2) Questions Identified in the September 1997 Council Policy, and (3) Program language identified by the Council's Independent Scientific Review Panel (ISRP). To meet the need for off-site mitigation for fish losses on the mainstem Columbia River, in a manner consistent with the objectives of the Council's Program, the Coeur d'Alene Tribe is proposing that the BPA fund the design, construction, operation, and maintenance of a trout production facility located adjacent to Coeur d'Alene Lake on the Coeur d'Alene Indian Reservation. The updated Master Plan (Item 3) represents the needs associated with the re-evaluation of the Coeur d'Alene Tribe's Trout Production Facility (No.199004402). This plan addresses issues and concerns expressed by the NWPPC as part of the issue summary for the Mountain Columbia provincial review, and the 3-step hatchery review process. Finally, item 4 (Appendices) documents the 3-Step process correspondence to date between the Coeur d'Alene Tribe and additional relevant entities. Item 4 provides a chronological account of previous ISRP reviews

  4. On organic emissions testing from indoor consumer products' use.

    PubMed

    Bartzis, J; Wolkoff, P; Stranger, M; Efthimiou, G; Tolis, E I; Maes, F; Nørgaard, A W; Ventura, G; Kalimeri, K K; Goelen, E; Fernandes, O

    2015-03-21

    A wide range of consumer and personal care products may, during their use, release significant amounts of volatile organic compounds (VOC) into the air. The identification and quantification of the emissions from such sources is typically performed in emission test chambers. A major question is to what degree the obtained emissions are reproducible and directly applicable to real situations. The present work attempts partly to address this question by comparison of selected VOC emissions in specific consumer products tested in chambers of various dimensions. The measurements were performed in three test chambers of different volumes (0.26-20 m(3)). The analytic performance of the laboratories was rigorously assessed prior to chamber testing. The results show emission variation for major VOC (terpenes); however, it remains in general, within the same order of magnitude for all tests. This variability does not seem to correlate with the chamber volume. It rather depends on the overall testing conditions. The present work is undertaken in the frame of EPHECT European Project.

  5. Tank vapor sampling and analysis data package for tank 241-C-106 waste retrieval sluicing system process test phase III

    SciTech Connect

    LOCKREM, L.L.

    1999-08-13

    This data package presents sampling data and analytical results from the March 28, 1999, vapor sampling of Hanford Site single-shell tank 241-C-106 during active sluicing. Samples were obtained from the 296-C-006 ventilation system stack and ambient air at several locations. Characterization Project Operations (CPO) was responsible for the collection of all SUMMATM canister samples. The Special Analytical Support (SAS) vapor team was responsible for the collection of all triple sorbent trap (TST), sorbent tube train (STT), polyurethane foam (PUF), and particulate filter samples collected at the 296-C-006 stack. The SAS vapor team used the non-electrical vapor sampling (NEVS) system to collect samples of the air, gases, and vapors from the 296-C-006 stack. The SAS vapor team collected and analyzed these samples for Lockheed Martin Hanford Corporation (LMHC) and Tank Waste Remediation System (TWRS) in accordance with the sampling and analytical requirements specified in the Waste Retrieval Sluicing System Vapor Sampling and Analysis Plan (SAP) for Evaluation of Organic Emissions, Process Test Phase III, HNF-4212, Rev. 0-A, (LMHC, 1999). All samples were stored in a secured Radioactive Materials Area (RMA) until the samples were radiologically released and received by SAS for analysis. The Waste Sampling and Characterization Facility (WSCF) performed the radiological analyses. The samples were received on April 5, 1999.

  6. The Influences of Arm Resist Motion on a CAR Crash Test Using Hybrid III Dummy with Human-Like Arm

    NASA Astrophysics Data System (ADS)

    Kim, Yongchul; Youm, Youngil; Bae, Hanil; Choi, Hyeonki

    Safety of the occupant during the crash is very essential design element. Many researches have been investigated in reducing the fatal injury of occupant. They are focusing on the development of a dummy in order to obtain the real human-like motion. However, they have not considered the arm resist motion during the car accident. In this study, we would like to suggest the importance of the reactive force of the arm in a car crash. The influences of reactive force acting on the human upper extremity were investigated using the impedance experimental method with lumped mass model of hand system and a Hybrid III dummy with human-like arm. Impedance parameters (e.g. inertia, spring constant and damping coefficient) of the elbow joint in maximum activation level were measured by free oscillation test using single axis robot. The results showed that without seat belt, the reactive force of human arm reduced the head, chest, and femur injury, and the flexion moment of the neck is higher than that of the conventional dummy.

  7. Highly stereoselective, cobalt(III)-directed Mannich additions in water yielding α-methylamino acid products.

    PubMed

    Oerum, Stephanie; Krabbe, Peter; Schau-Magnussen, Magnus; Furbo, Søren; Bendix, Jesper; Hammershøi, Anders

    2013-01-01

    Highly stereoselective and rapid (<1 min) addition reactions to the imine double bond of 2-(methylimino)acetate complexes [L(4)Co(O(2)CCH=NCH(3))](2+) [L(4) = (en)(2) (7), (tren) (11)] were achieved in aqueous solution with nitromethane, ethyl 3-oxobutanoate or diethyl malonate. The molecular structures of two product complexes, rac-(Δ*-R(C)*-S(N)*)-[Co(en)(2)(O(2)CCH[CH(2)NO(2)]NHCH(3))]ZnCl(4) and rac-(Δ*-R(C)*-S(N)*)-[Co(en)(2)(O(2)CCH[CH(2)COCH(3)]NHCH(3))]ZnCl(4), were established by X-ray diffraction.

  8. Energy Distribution among Reaction Products. III: The Method of Measured Relaxation Applied to H + Cl2

    NASA Technical Reports Server (NTRS)

    Pacey, P. D.; Polyani, J. C.

    1971-01-01

    The method of measured relaxation is described for the determination of initial vibrational energy distribution in the products of exothermic reaction. Hydrogen atoms coming from an orifice were diffused into flowing chlorine gas. Measurements were made of the resultant ir chemiluminescence at successive points along the line of flow. The concurrent processes of reaction, diffusion, flow, radiation, and deactivation were analyzed in some detail on a computer. A variety of relaxation models were used in an attempt to place limits on k(nu prime), the rate constant for reaction to form HCl in specified vibrational energy levels: H+Cl2 yields (sup K(nu prime) HCl(sub nu prime) + Cl. The set of k(?) obtained from this work is in satisfactory agreement with those obtained by another experimental method (the method of arrested relaxation described in Parts IV and V of the present series.

  9. Inclusive Particle Production at Forward Angles from Collisions ofli ght Relativistic Nuclei, Part III: Data Tables

    SciTech Connect

    Anderson, L.; Moeller, E.; Nagamiya, S.; Nissen-Meyer, S.; Schroeder, L.; Shapiro, G.; Steiner, H.

    1982-05-01

    This document contains data tables on microfiche of single particle inclusive cross sections of protons, deuterons, tritons, {sup 3}He, {sup 4}He, {sup 6}He, {sup 8}He, and {pi}{sup -}. The production of these fragments was measured in collisions of 1.05 GeV/A and 2.1 GeV/A proton, deuteron, alpha and carbon projectiles as well as 0.4 GeV/A alpha particles on targets of C, Cu, Pb, and H (from a CH{sub 2}-C subtraction), using a double focusing spectrometer. Only fragment emission in the region 0.5 {le} (p/Z){sub lab} {le} 8.7 GV/c and 0{sup o} {le} {var_theta}{sub lab} {le} 12{sup o} is included.

  10. Bioeconomic evaluation of embryo transfer in beef production systems: III. Embryo lines for producing bulls.

    PubMed

    Ruvuna, F; Taylor, J F; Walter, J P; Turner, J W; Thallman, R M

    1992-04-01

    A model was developed for the economic evaluation of embryos for producing bull lines for use in commercial beef production. The fundamental concept underlying the model is that a cloned and sexed embryo of known genetic characteristics for beef traits is used to produce a bull. After reaching physiological maturity, the bull is used in natural matings. Equations relating feed energy requirements and growth rates based on NRC requirements and costs and returns discounted to present value allow investigation of expected economic merits of progeny from different embryo bull lines. The model has the flexibility to determine optimal embryo characteristics for different production environments. Model sensitivity to variation in progeny sex ratios, growth rates, yield and quality grades, and herd fertility characteristics was examined. Net present values (NPV) per embryo transferred were determined at the optimal marketing age of progeny produced from mating the bull to 30 cows per year for 5 yr. Relative to the lowest NPV of $18,209 for progeny with an expected quality grade of Select and yield grade of 4 at 400 d, increments in NPV ranged from $329 to $22,708 depending on differences in expected progeny carcass grade characteristics. The difference between NPV for 100% male and 40% male sex ratios was $7,518. The NPV differences between progeny growth rates of 1.6 and .9 kg/d holding herd conception rate constant at .9 and .5 were $8,311 and $4,611, respectively. The model evaluates relative economic values of embryo lines for producing bulls, accommodating interactions among progeny characteristics, and environments.

  11. A Confirmatory Factor Analysis of Cattell-Horn-Carroll Theory and Cross-Age Invariance of the Woodcock-Johnson Tests of Cognitive Abilities III

    ERIC Educational Resources Information Center

    Taub, Gordon E.; McGrew, Kevin S.

    2004-01-01

    Establishing an instrument's factorial invariance provides the empirical foundation to compare an individual's score across time or to examine the pattern of correlations between variables in differentiated age groups. In the recently published Woodcock-Johnson Tests of Cognitive Ability (WJ COG) and Achievement (WJ ACH) Third Edition (III) the…

  12. Validation of the WMS-III Facial Memory subtest with the Graduate Hospital Facial Memory Test in a sample of right and left anterior temporal lobectomy patients.

    PubMed

    Chiaravalloti, Nancy D; Tulsky, David S; Glosser, Guila

    2004-06-01

    A number of studies have shown visuospatial memory deficits following anterior temporal lobectomy (ATL) in the right, nondominant temporal lobe (RATL). The current study examines 26 patients with intractable temporal lobe epilepsy who underwent ATL in either the right (RATL, n = 16) or left temporal lobe (LATL, n = 10) on two tests of facial memory abilities, the Wechsler Memory Scale-III (WMS-III) Faces subtest and the Graduate Hospital Facial Memory Test (FMT). Repeated measures ANOVA on the FMT indicated a significant main effect of side of surgery. The RATL group performed significantly below the LATL group overall. Both groups showed a slight, but non-significant, improvement in performance from pre- to postsurgery on the FMT immediate memory, likely due to practice effects. Repeated measures ANOVA on the WMS-III Faces subtest revealed a significant interaction of group (RATL vs. LATL) by delay (immediate vs. delayed). Overall, the LATL group showed an improvement in recognition scores from immediate to delayed memory, whereas the RATL group performed similarly at both immediate and delayed testing. No effects of surgery were noted on the WMS-III. Following initial data analysis the WMS-III Faces I and II data were re-scored using the scoring suggested by Holdnack and Delis (2003), earlier in this issue. Repeated measures ANOVA revealed a trend toward significance in the three-way interaction of group (RATL vs. LATL) x time of testing (pre- versus postop) x delay (immediate vs. delayed memory). On the Faces I subtest, both the RATL and LATL groups showed a decline from preoperative to postoperative testing. However, on Faces II the LATL group showed an increase in performance from preoperative to postoperative testing, while the RALT group showed a decline in performance from preoperative to postoperative testing. While the FMT appears to be superior to the WMS-III Faces subtest in identifying deficits in facial memory prior to and following RATL, the

  13. Feasibility of closed Fe(II)/Fe(III) system for product-reflux in Nitrox process

    SciTech Connect

    Adachi, M.; Ishida, T.

    1981-03-10

    A concept of closed reflux system for stable isotope fractionation by chemical exchange method has been introduced. In a closed system a chemical agent used to convert one chemical species of an isotopic exchange reaction into the other at the product end is regenerated on site by means of an electrochemical or thermal process. It offers a convenience of eliminating the needs for transporting chemicals to and from the site and an advantage of allowing leniency in the degree of completeness of the reflux reaction. Feasibility of use of Fe(II) salt solutions in a closed reflux system for the Nitrox process for /sup 15/N fractionation has been studied. Two of such systems, FeSO/sub 4/ in H/sub 2/SO/sub 4/ and Fe(ClO/sub 4/)/sub 2/ in HClO/sub 4/, are adopted for packed column operation. For both systems, the rate of reduction of nitric acid increases with increasing acid concentration, the solubility of the salts decreases with the increasing acid concentration, and the reflux reaction can be made to go to completion. Evaluation of such a closed reflux system will have to include that of performance of regenerative process.

  14. Test Review: Woodcock, R. W., Schrank, F. A., Mather, N., & McGrew, K. S. 2007). "Woodcock-Johnson III Tests of Achievement, Form C/Brief Battery." Rolling Meadows, IL: Riverside

    ERIC Educational Resources Information Center

    Grenwelge, Cheryl H.

    2009-01-01

    The Woodcock Johnson III Brief Assessment is a "maximum performance test" (Reynolds, Livingston, Willson, 2006) that is designed to assess the upper levels of knowledge and skills of the test taker using both power and speed to obtain a large amount of information in a short period of time. The Brief Assessment also provides an adequate…

  15. Color-Multiplexing-Based Fluorescent Test Paper: Dosage-Sensitive Visualization of Arsenic(III) with Discernable Scale as Low as 5 ppb.

    PubMed

    Zhou, Yujie; Huang, Xiaoyan; Liu, Cui; Zhang, Ruilong; Gu, Xiaoling; Guan, Guijian; Jiang, Changlong; Zhang, Liying; Du, Shuhu; Liu, Bianhua; Han, Ming-Yong; Zhang, Zhongping

    2016-06-21

    Fluorescent colorimetry test papers are promising for the assays of environments, medicines, and foods by the observation of the naked eye on the variations of fluorescence brightness and color. Unlike dye-absorption-based pH test paper, however, the fluorescent test papers with wide color-emissive variations with target dosages for accurate quantification remain unsuccessful even if the multicolorful fluorescent probes are used. Here, we report the dosage-sensitive fluorescent colorimetry test paper with a very wide/consecutive "from red to cyan" response to the presence and amount of arsenic ions, As(III). Red quantum dots (QDs) were modified with glutathione and dithiothreitol to obtain the supersensitivity to As(III) by the quenching of red fluorescence through the formation of dispersive QDs aggregates. A small amount of cyan carbon dots (CDs) with spectral blue-green components as the photostable internal standard were mixed into the QDs solution to produce a composited red fluorescence. Upon the addition of As(III) into the sensory solution, the fluorescence color could gradually be reversed from red to cyan with a detection limit of 1.7 ppb As(III). When the sensory solution was printed onto a piece of filter paper, surprisingly a serial of color evolution from peach to pink to orange to khaki to yellowish to yellow-green to final cyan with the addition of As(III) was displayed and clearly discerned the dosage scale as low as 5 ppb. The methodology reported here opens a novel pathway toward the real applications of fluorescent test papers. PMID:27230307

  16. Testing and production performance of slim-hole wells

    SciTech Connect

    Azari, M.; Soliman, M.; Wendler, C.

    1995-12-31

    The petroleum industry is focusing on cost reduction and efficiency more than it ever had. Slim-hole drilling and completion technology offer significant cost reduction potentials to the oil and gas industry. To provide an insight into slim-hole technology, production, stimulation, conformance, perforation, and testing aspects of reservoirs with wellbore and completion string diameters of less than conventionally drilled and completed wells are detailed here. Productivity of both horizontal and vertical slim-hole wells, with and without hydraulic fractures, is compared with wells having standard wellbore sizes. Comparisons with conventional sized wellbores will be given that concern: (1) wellbore hydraulics, including nodal analysis and minimum gas rates required to lift fluids off the well, (2) the effect of wellbore diameter on transient pressure testing, and (3) coning and cresting problems. The performance of slim-hole wells compares favorably to standard wellbore completions for the parameters investigated in this study.

  17. A products generator for testing the performance of disassembly procedures

    NASA Astrophysics Data System (ADS)

    Adenso-Díaz, Belarmino; González Torre, Beatriz

    2004-12-01

    In recent decades, regulations and markets have been exerting pressure on designers and manufacturers to take more responsibility for the environmental impacts of their products throughout their life cycles. The problem of finding the disassembly sequence represents one of the major challenges when attempting to close product life cycles by carrying out reuse, recycling and remanufacturing practices. Many different techniques have been used to deal with this problem, varying from exact to heuristic solutions. So far, however, not much effort has gone into measuring and comparing the efficiency of this wide set of techniques. This is partly due to the difficulties of getting a wide population of real products, belonging to different industries and with different degree of complexity that might constitute a representative population for carrying out this kind of task. In this paper, a generator of complex products is presented that is able to build up products with hundreds of components joined by different kinds of joints in such a way that a theoretical "good" disassembly sequence is always known. The efficiency of different methods for general products can thus be easily compared. The performance of a Scatter Search algorithm is tested as an example of its application in this case.

  18. 21 CFR 640.82 - Tests on final product.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 7 2013-04-01 2013-04-01 false Tests on final product. 640.82 Section 640.82 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) BIOLOGICS... Evaluation and Research, Food and Drug Administration. (c) pH. The pH shall be 6.9 ±0.5 when measured in...

  19. 21 CFR 640.82 - Tests on final product.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 7 2012-04-01 2012-04-01 false Tests on final product. 640.82 Section 640.82 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) BIOLOGICS... Evaluation and Research, Food and Drug Administration. (c) pH. The pH shall be 6.9 ±0.5 when measured in...

  20. 21 CFR 640.82 - Tests on final product.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 7 2011-04-01 2010-04-01 true Tests on final product. 640.82 Section 640.82 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) BIOLOGICS... Evaluation and Research, Food and Drug Administration. (c) pH. The pH shall be 6.9 ±0.5 when measured in...

  1. 21 CFR 640.82 - Tests on final product.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 7 2010-04-01 2010-04-01 false Tests on final product. 640.82 Section 640.82 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) BIOLOGICS... Evaluation and Research, Food and Drug Administration. (c) pH. The pH shall be 6.9 ±0.5 when measured in...

  2. Durability Testing of Fluidized Bed Steam Reforming Products

    SciTech Connect

    JANTZEN, CAROL M.; PAREIZS, JOHN M.; LORIER, TROY H.; MARRA, JAMES C.

    2005-07-01

    Fluidized Bed Steam Reforming (FBSR) is being considered as a potential technology for the immobilization of a wide variety of radioactive wastes but especially aqueous high sodium wastes at the Hanford site, at the Idaho National Laboratory (INL), and at the Savannah River Site (SRS). The FBSR technology converts organic compounds to CO{sub 2} and H{sub 2}O, converts nitrate/nitrite species to N{sub 2}, and produces a solid residue through reactions with superheated steam, the fluidizing media. If clay is added during processing a ''mineralized'' granular waste form can be produced. The mineral components of the waste form are primarily Na-Al-Si (NAS) feldspathoid minerals with cage-like and ring structures and iron bearing spinel minerals. The cage and ring structured minerals atomically bond radionuclides like Tc{sup 99} and Cs{sup 137} and anions such as SO{sub 4}, I, F, and Cl. The spinel minerals appear to stabilize Resource Conservation and Recovery Act (RCRA) hazardous species such as Cr and Ni. Durability testing of the FBSR products was performed using ASTM C1285 (Product Consistency Test) and the Environmental Protection Agency (EPA) Toxic Characteristic Leaching Procedure (TCLP). The FBSR mineral products (bed and fines) evaluated in this study were found to be two orders of magnitude more durable than the Hanford Low Activity Waste (LAW) glass requirement of 2 g/m{sup 2} release of Na{sup +}. The PCT responses for the FBSR samples tested were consistent with results from previous FBSR Hanford LAW product testing. Differences in the response can be explained by the minerals formed and their effects on PCT leachate chemistry.

  3. Standard test method for saponification number of petroleum products

    SciTech Connect

    Not Available

    1980-01-01

    This method covers the determination of the amount of constituents in petroleum products that will saponify under the conditions of the test. Since compounds of sulfur, phosphorus, the halogens, and certain other elements which are sometimes added to petroleum products also consume alkali and acids, the results obtained indicate the effect of these extraneous materials in addition to the saponifiable material present. Results on products containing such materials, on used internal-combustion-engine crank-case oils, and on used turbine oils must be interpreted in this respect. Summary of method: a known weight of the sample, dissolved in methylethylketone is heated with a known amount of alcoholic potassium hydroxide (KOH). The excess alkali is titrated with standard acid and the saponification number calculated.

  4. Farmview product testing for a new spaced based information business

    NASA Astrophysics Data System (ADS)

    Knoblauch, Gregory E.; Grace, John A.

    1996-03-01

    RESOURCE21, Inc. is planning to launch a constellation of four satellites to provide frequent and timely information to managers of earth resources for agricultural croplands and forests. Raw satellite data collected twice weekly will be processed into value added information and delivered electronically to customers within hours after satellite acquisition. This information can be used for real time or long range management decisions. Real time management decisions could include herbicide or insecticide applications, additional fertilizer applications, and/or irrigated water management. (Grace 1994) Long range management decisions could include future fertility programs or water management systems. RESOURCE21 is planning a satellite launch in 1998. Considerable work has been conducted in the development of products, potential retail markets, and delivery systems that will generate revenue streams to support this innovative satellite business. This paper will discuss how satellite prototype products were developed and refined over a four year product test program.

  5. Testing the product of slopes in related regressions.

    PubMed

    Morrell, Christopher H; Shetty, Veena; Phillips, Terry; Arumugam, Thiruma V; Mattson, Mark P; Wan, Ruiqian

    2013-09-01

    A study was conducted of the relationships among neuroprotective factors and cytokines in brain tissue of mice at different ages that were examined on the effect of dietary restriction on protection after experimentally induced brain stroke. It was of interest to assess whether the cross-product of the slopes of pairs of variables vs. age was positive or negative. To accomplish this, the product of the slopes was estimated and tested to determine if it is significantly different from zero. Since the measurements are taken on the same animals, the models used must account for the non-independence of the measurements within animals. A number of approaches are illustrated. First a multivariate multiple regression model is employed. Since we are interested in a nonlinear function of the parameters (the product) the delta method is used to obtain the standard error of the estimate of the product. Second, a linear mixed-effects model is fit that allows for the specification of an appropriate correlation structure among repeated measurements. The delta method is again used to obtain the standard error. Finally, a non-linear mixed-effects approach is taken to fit the linear-mixed-effects model and conduct the test. A simulation study investigates the properties of the procedure. PMID:25346580

  6. Production of LEU Fully Ceramic Microencapsulated Fuel for Irradiation Testing

    SciTech Connect

    Terrani, Kurt A; Kiggans Jr, James O; McMurray, Jake W; Jolly, Brian C; Hunt, Rodney Dale; Trammell, Michael P; Snead, Lance Lewis

    2016-01-01

    Fully Ceramic Microencapsulated (FCM) fuel consists of tristructural isotropic (TRISO) fuel particles embedded inside a SiC matrix. This fuel inherently possesses multiple barriers to fission product release, namely the various coating layers in the TRISO fuel particle as well as the dense SiC matrix that hosts these particles. This coupled with the excellent oxidation resistance of the SiC matrix and the SiC coating layer in the TRISO particle designate this concept as an accident tolerant fuel (ATF). The FCM fuel takes advantage of uranium nitride kernels instead of oxide or oxide-carbide kernels used in high temperature gas reactors to enhance heavy metal loading in the highly moderated LWRs. Production of these kernels with appropriate density, coating layer development to produce UN TRISO particles, and consolidation of these particles inside a SiC matrix have been codified thanks to significant R&D supported by US DOE Fuel Cycle R&D program. Also, surrogate FCM pellets (pellets with zirconia instead of uranium-bearing kernels) have been neutron irradiated and the stability of the matrix and coating layer under LWR irradiation conditions have been established. Currently the focus is on production of LEU (7.3% U-235 enrichment) FCM pellets to be utilized for irradiation testing. The irradiation is planned at INL s Advanced Test Reactor (ATR). This is a critical step in development of this fuel concept to establish the ability of this fuel to retain fission products under prototypical irradiation conditions.

  7. Transient productivity index for numerical well test simulations

    SciTech Connect

    Blanc, G.; Ding, D.Y.; Ene, A.

    1997-08-01

    The most difficult aspect of numerical simulation of well tests is the treatment of the Bottom Hole Flowing (BHF) Pressure. In full field simulations, this pressure is derived from the Well-block Pressure (WBP) using a numerical productivity index which accounts for the grid size and permeability, and for the well completion. This productivity index is calculated assuming a pseudo-steady state flow regime in the vicinity of the well and is therefore constant during the well production period. Such a pseudo-steady state assumption is no longer valid for the early time of a well test simulation as long as the pressure perturbation has not reached several grid-blocks around the well. This paper offers two different solutions to this problem: (1) The first one is based on the derivation of a Numerical Transient Productivity Index (NTPI) to be applied to Cartesian grids; (2) The second one is based on the use of a Corrected Transmissibility and Accumulation Term (CTAT) in the flow equation. The representation of the pressure behavior given by both solutions is far more accurate than the conventional one as shown by several validation examples which are presented in the following pages.

  8. Development and Testing of the VAHIRR Radar Product

    NASA Technical Reports Server (NTRS)

    Barrett, Joe III; Miller, Juli; Charnasky, Debbie; Gillen, Robert; Lafosse, Richard; Hoeth, Brian; Hood, Doris; McNamara, Todd

    2008-01-01

    Lightning Launch Commit Criteria (LLCC) and Flight Rules (FR) are used for launches and landings at government and commercial spaceports. They are designed to avoid natural and triggered lightning strikes to space vehicles, which can endanger the vehicle, payload, and general public. The previous LLCC and FR were shown to be overly restrictive, potentially leading to costly launch delays and scrubs. A radar algorithm called Volume Averaged Height Integrated Radar Reflectivity (VAHIRR), along with new LLCC and FR for anvil clouds, were developed using data collected by the Airborne Field Mill II research program. VAHIRR is calculated at every horizontal position in the coverage area of the radar and can be displayed similar to a two-dimensional derived reflectivity product, such as composite reflectivity or echo tops. It is the arithmetic product of two quantities not currently generated by the Weather Surveillance Radar 1988 Doppler (WSR-88D): a volume average of the reflectivity measured in dBZ and the average cloud thickness based on the average echo top height and base height. This presentation will describe the VAHIRR algorithm, and then explain how the VAHIRR radar product was implemented and tested on a clone of the National Weather Service's (NWS) Open Radar Product Generator (ORPG-clone). The VAHIRR radar product was then incorporated into the Advanced Weather Interactive Processing System (AWIPS), to make it more convenient for weather forecasters to utilize. Finally, the reliability of the VAHIRR radar product was tested with real-time level II radar data from the WSR-88D NWS Melbourne radar.

  9. Assessing Potential Impacts of CO2 Leakage on Shallow Groundwater Quality in the SECARB Phase III Early Test site Using Single-well Push-Pull Tests

    NASA Astrophysics Data System (ADS)

    Yang, C.; Mickler, P. J.; Reedy, R. C.; Scanlon, B. R.

    2012-12-01

    A single-well push-pull test was conducted in the Cranfield shallow aquifer, the SECARB Phase III early test site, for assessing potential impacts of CO2 leakage on groundwater quality. A total of 3800 liter of groundwater equilibrated with CO2 gas at a partial pressure of 1.105 Pa was injected into a confined sand interval at ~ 70 m depth. NaBr solution was added to the injected solution as tracer. The injected groundwater incubated within the interval for about two days. Chemical parameters (pH, temperature, alkalinity, and electric conductivity) were measured on-site and water samples were collected for chemical (major ions, trace elements, and dissolved inorganic carbon, DIC) as well as for stable carbon isotopic analyses. Mineralogical analyses using XR-D and SEM techniques indicate that aquifer sediments are dominated by silicates. Concentrations of the Br tracer in the recovered samples show mixing of background water with the injected solution. Major ions, especially, Ca, Mg, K, and Si show obvious enrichment, indicating that mobilization of these ions occurred from aquifer sediments to groundwater and may be dominated by dissolution of silicates and possible carbonate minerals. δ13C of DIC of the recovered samples may also suggest potential dissolution of carbonates. Concentrations of trace elements show mobilization after injection of CO2 enriched groundwater. Mobilization of trace elements could be due to co-dissolution of silicates and carbonates and desorption from the surface of aquifer sediments. However, mass balance calculations suggest that ion mobilization is limited and; therefore, potential risks of CO2 are low, especially for arsenic and lead with concentrations in the recovered samples ~30 times less than the EPA maximum contamination level. Results of the single-well push-pull test were also compared to a laboratory batch experiment of water-rock-CO2 interactions. Overall reaction rates of most ions estimated are higher in the batch

  10. TESTING MASS LOSS IN LARGE MAGELLANIC CLOUD CEPHEIDS USING INFRARED AND OPTICAL OBSERVATIONS. II. PREDICTIONS AND TESTS OF THE OGLE-III FUNDAMENTAL-MODE CEPHEIDS

    SciTech Connect

    Neilson, Hilding R.; Ngeow, Chow-Choong; Kanbur, Shashi M.; Lester, John B.

    2010-06-20

    In this paper, we test the hypothesis that Cepheids have infrared excesses due to mass loss. We fit a model using the mass-loss rate and the stellar radius as free parameters to optical observations from the OGLE-III survey and infrared observations from the Two Micron All Sky Survey and SAGE data sets. The sample of Cepheids has predicted minimum mass-loss rates ranging from 0 to 10{sup -8} M{sub sun} yr{sup -1}, where the rates depend on the chosen dust properties. We use the predicted radii to compute the period-radius relation for LMC Cepheids and to estimate the uncertainty caused by the presence of infrared excess for determining angular diameters with the infrared surface brightness technique. Finally, we calculate the linear and nonlinear period-luminosity (P-L) relations for the LMC Cepheids at VIJHK + IRAC wavelengths and find that the P-L relations are consistent with being nonlinear at infrared wavelengths contrary to previous results.

  11. Bacterial ability in AsIII oxidation and AsV reduction: Relation to arsenic tolerance, P uptake, and siderophore production.

    PubMed

    Ghosh, Piyasa; Rathinasabapathi, Bala; Teplitski, Max; Ma, Lena Q

    2015-11-01

    The relationship between bacterial ability in arsenic transformation, siderophore production, and P uptake was investigated using six arsenic-resistant bacteria isolated from the rhizosphere of arsenic-hyperaccumulator Pteris vittata. Bacterial strains of PG5 and 12 were better arsenite (AsIII) oxidizers (31-46 vs. 6.2-21% of 1 mM AsIII) whereas PG 6, 9, 10 and 16 were better arsenate (AsV) reducers (58-95 vs. 7.5-46% of 1 mM AsV). Increase in AsV concentration from 0 to 1 mM induced 3.0-8.4 times more P uptake by bacteria but increase in P concentration from 0.1 to 1 mM reduced AsV uptake by 17-71%, indicating that P and AsV were taken up by P transporters. Bacteria producing more siderophores (PG5 and 12; >73 μM equiv) showed greater AsIII oxidation and AsIII resistance than those producing less siderophore (PG 6, 9, 10 and 16; <23 μM equiv). This observation was further supported by results obtained from mutants of Pseudomonas fluorescens impaired in siderophore production, as they were 23-25% less tolerant to AsIII than the wild-type. Arsenic-resistant bacteria increased their arsenic tolerance by retaining less arsenic in cells via efficient AsIII oxidation and AsV reduction, which were impacted by P uptake and siderophore production. PMID:25576133

  12. Arsenic (III, V), indium (III), and gallium (III) toxicity to zebrafish embryos using a high-throughput multi-endpoint in vivo developmental and behavioral assay.

    PubMed

    Olivares, Christopher I; Field, Jim A; Simonich, Michael; Tanguay, Robert L; Sierra-Alvarez, Reyes

    2016-04-01

    Gallium arsenide (GaAs), indium gallium arsenide (InGaAs) and other III/V materials are finding increasing application in microelectronic components. The rising demand for III/V-based products is leading to increasing generation of effluents containing ionic species of gallium, indium, and arsenic. The ecotoxicological hazard potential of these streams is unknown. While the toxicology of arsenic is comprehensive, much less is known about the effects of In(III) and Ga(III). The embryonic zebrafish was evaluated for mortality, developmental abnormalities, and photomotor response (PMR) behavior changes associated with exposure to As(III), As(V), Ga(III), and In(III). The As(III) lowest observable effect level (LOEL) for mortality was 500 μM at 24 and 120 h post fertilization (hpf). As(V) exposure was associated with significant mortality at 63 μM. The Ga(III)-citrate LOEL was 113 μM at 24 and 120 hpf. There was no association of significant mortality over the tested range of In(III)-citrate (56-900 μM) or sodium citrate (213-3400 μM) exposures. Only As(V) resulted in significant developmental abnormalities with LOEL of 500 μM. Removal of the chorion prior to As(III) and As(V) exposure was associated with increased incidence of mortality and developmental abnormality suggesting that the chorion may normally attenuate mass uptake of these metals by the embryo. Finally, As(III), As(V), and In(III) caused PMR hypoactivity (49-69% of control PMR) at 900-1000 μM. Overall, our results represent the first characterization of multidimensional toxicity effects of III/V ions in zebrafish embryos helping to fill a significant knowledge gap, particularly in Ga(III) and In(III) toxicology.

  13. Arsenic (III, V), indium (III), and gallium (III) toxicity to zebrafish embryos using a high-throughput multi-endpoint in vivo developmental and behavioral assay.

    PubMed

    Olivares, Christopher I; Field, Jim A; Simonich, Michael; Tanguay, Robert L; Sierra-Alvarez, Reyes

    2016-04-01

    Gallium arsenide (GaAs), indium gallium arsenide (InGaAs) and other III/V materials are finding increasing application in microelectronic components. The rising demand for III/V-based products is leading to increasing generation of effluents containing ionic species of gallium, indium, and arsenic. The ecotoxicological hazard potential of these streams is unknown. While the toxicology of arsenic is comprehensive, much less is known about the effects of In(III) and Ga(III). The embryonic zebrafish was evaluated for mortality, developmental abnormalities, and photomotor response (PMR) behavior changes associated with exposure to As(III), As(V), Ga(III), and In(III). The As(III) lowest observable effect level (LOEL) for mortality was 500 μM at 24 and 120 h post fertilization (hpf). As(V) exposure was associated with significant mortality at 63 μM. The Ga(III)-citrate LOEL was 113 μM at 24 and 120 hpf. There was no association of significant mortality over the tested range of In(III)-citrate (56-900 μM) or sodium citrate (213-3400 μM) exposures. Only As(V) resulted in significant developmental abnormalities with LOEL of 500 μM. Removal of the chorion prior to As(III) and As(V) exposure was associated with increased incidence of mortality and developmental abnormality suggesting that the chorion may normally attenuate mass uptake of these metals by the embryo. Finally, As(III), As(V), and In(III) caused PMR hypoactivity (49-69% of control PMR) at 900-1000 μM. Overall, our results represent the first characterization of multidimensional toxicity effects of III/V ions in zebrafish embryos helping to fill a significant knowledge gap, particularly in Ga(III) and In(III) toxicology. PMID:26824274

  14. Production of dengue virus envelope protein domain III-based antigens in tobacco chloroplasts using inducible and constitutive expression systems.

    PubMed

    Gottschamel, Johanna; Lössl, Andreas; Ruf, Stephanie; Wang, Yanliang; Skaugen, Morten; Bock, Ralph; Clarke, Jihong Liu

    2016-07-01

    Dengue fever is a disease in many parts of the tropics and subtropics and about half the world's population is at risk of infection according to the World Health Organization. Dengue is caused by any of the four related dengue virus serotypes DEN-1, -2, -3 and -4, which are transmitted to people by Aedes aegypti mosquitoes. Currently there is only one vaccine (Dengvaxia(®)) available (limited to a few countries) on the market since 2015 after half a century's intensive efforts. Affordable and accessible vaccines against dengue are hence still urgently needed. The dengue envelop protein domain III (EDIII), which is capable of eliciting serotype-specific neutralizing antibodies, has become the focus for subunit vaccine development. To contribute to the development of an accessible and affordable dengue vaccine, in the current study we have used plant-based vaccine production systems to generate a dengue subunit vaccine candidate in tobacco. Chloroplast genome engineering was applied to express serotype-specific recombinant EDIII proteins in tobacco chloroplasts using both constitutive and ethanol-inducible expression systems. Expression of a tetravalent antigen fusion construct combining EDIII polypeptides from all four serotypes was also attempted. Transplastomic EDIII-expressing tobacco lines were obtained and homoplasmy was verified by Southern blot analysis. Northern blot analyses showed expression of EDIII antigen-encoding genes. EDIII protein accumulation levels varied for the different recombinant EDIII proteins and the different expression systems, and reached between 0.8 and 1.6 % of total cellular protein. Our study demonstrates the suitability of the chloroplast compartment as a production site for an EDIII-based vaccine candidate against dengue fever and presents a Gateway(®) plastid transformation vector for inducible transgene expression. PMID:27116001

  15. The gallium(III)-salicylidene acylhydrazide complex shows synergistic anti-biofilm effect and inhibits toxin production by Pseudomonas aeruginosa.

    PubMed

    Rzhepishevska, Olena; Hakobyan, Shoghik; Ekstrand-Hammarström, Barbro; Nygren, Yvonne; Karlsson, Torbjörn; Bucht, Anders; Elofsson, Mikael; Boily, Jean-François; Ramstedt, Madeleine

    2014-09-01

    Bacterial biofilms cause a range of problems in many areas and especially in health care. Biofilms are difficult to eradicate with traditional antibiotics and consequently there is a need for alternative ways to prevent and/or remove bacterial biofilms. Furthermore, the emergence of antibiotic resistance in bacteria creates a challenge to find new types of antibiotics with a lower evolutionary pressure for resistance development. One route to develop such drugs is to target the so called virulence factors, i.e. bacterial systems used when bacteria infect a host cell. This study investigates synergy effects between Ga(III) ions, previously reported to suppress biofilm formation and growth in bacteria, and salicylidene acylhydrazides (hydrazones) that have been proposed as antivirulence drugs targeting the type three secretion system used by several Gram-negative pathogens, including Pseudomonas aerugionosa, during bacterial infection of host cells. A library of hydrazones was screened for: Fe(III) binding, enhanced anti-biofilm effect with Ga(III) on P. aeruginosa, and low cytotoxicity to mammalian cells. The metal coordination for the most promising ligand, 2-Oxo-2-[N-(2,4,6-trihydroxy-benzylidene)-hydrazino]-acetamide (ME0163) with Ga(III) was investigated using extended X-ray absorption fine structure spectroscopy as well as density functional theory. The results showed that Ga(III) chelates the hydrazone with 5- and 6-membered chelating rings, and that the Ga(III)-ME0163 complex enhanced the antibiofilm effect of Ga(III) while suppressing the type three secretion system in P. aeruginosa. The latter effect was not observed for the hydrazone alone and was similar for Ga(III)-citrate and Ga(III)-ME0163 complexes, indicating that the inhibition of virulence was caused by Ga(III).

  16. City of North Bonneville, Washington: Geothermal Exploration production test well

    NASA Astrophysics Data System (ADS)

    1982-06-01

    Based on discussions with the City of North Bonneville, the production test well was drilled to a depth that would also explore for ground water temperatures near 130 F (54.4 C). Depth projections to a 130 F bottom hole temperature were made by assuming a constant ground water temperature rise greater than 50 C per kilometer, and by assuming that essentially homogeneous or equivalent conductive rock units would be encountered. Minimum water production requirements were not set, although the City determined that about 800 gpm would be acceptable. Larger upper casing diameters of 16 and 12 inches were installed in order to provide the future use of either a vertical turbine or submersible pump, as desired by the city. The scope of work included interpretation of well characteristics, evaluation of ground water as a geothermal resource, geologic analysis of data from drilling and testing, drilling supervision, daily drilling cost accounting, and preparation of a final report. The report includes geologic evaluation of the drilling and test data, ground water and geothermal potential.

  17. Increasing Heavy Oil Reserves in the Wilmington Oil Field Through Advanced Reservoir Characterization and Thermal Production Technologies, Class III

    SciTech Connect

    City of Long Beach; Tidelands Oil Production Company; University of Southern California; David K. Davies and Associates

    2002-09-30

    The objective of this project was to increase the recoverable heavy oil reserves within sections of the Wilmington Oil Field, near Long Beach, California through the testing and application of advanced reservoir characterization and thermal production technologies. The successful application of these technologies would result in expanding their implementation throughout the Wilmington Field and, through technology transfer, to other slope and basin clastic (SBC) reservoirs.

  18. Increasing Heavy Oil Reserves in the Wilmington Oil Field Through Advanced Reservoir Characterization and Thermal Production Technologies, Class III

    SciTech Connect

    City of Long Beach; Tidelands Oil Production Company; University of Southern California; David K. Davies and Associates

    2002-09-30

    The objective of this project was to increase the recoverable heavy oil reserves within sections of the Wilmington Oil Field, near Long Beach, California through the testing and application of advanced reservoir characterization and thermal production technologies. It was hoped that the successful application of these technologies would result in their implementation throughout the Wilmington Field and, through technology transfer, will be extended to increase the recoverable oil reserves in other slope and basin clastic (SBC) reservoirs.

  19. 30 CFR 250.1151 - How often must I conduct well production tests?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 2 2013-07-01 2013-07-01 false How often must I conduct well production tests... Gas Production Requirements Well Tests and Surveys § 250.1151 How often must I conduct well production tests? (a) You must conduct well production tests as shown in the following table: You must conduct:...

  20. 30 CFR 250.1151 - How often must I conduct well production tests?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 2 2014-07-01 2014-07-01 false How often must I conduct well production tests... Gas Production Requirements Well Tests and Surveys § 250.1151 How often must I conduct well production tests? (a) You must conduct well production tests as shown in the following table: You must conduct:...

  1. 30 CFR 250.1151 - How often must I conduct well production tests?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 2 2011-07-01 2011-07-01 false How often must I conduct well production tests... SHELF Oil and Gas Production Requirements Well Tests and Surveys § 250.1151 How often must I conduct well production tests? (a) You must conduct well production tests as shown in the following table:...

  2. 30 CFR 250.1151 - How often must I conduct well production tests?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 2 2012-07-01 2012-07-01 false How often must I conduct well production tests... Gas Production Requirements Well Tests and Surveys § 250.1151 How often must I conduct well production tests? (a) You must conduct well production tests as shown in the following table: You must conduct:...

  3. Mechanism of Au(III) reduction by chitosan: comprehensive study with 13C and 1H NMR analysis of chitosan degradation products.

    PubMed

    Pestov, Alexander; Nazirov, Alexander; Modin, Evgeny; Mironenko, Alexander; Bratskaya, Svetlana

    2015-03-01

    The mechanism of Au(III) reduction by chitosan has been proposed on the basis of comprehensive study of kinetics of Au(III) reduction and chitosan chain degradation using UV-vis spectroscopy and viscosimetry, and identification of reaction products using colloid titration and (13)C, (1)H NMR spectroscopy. We have shown that formation of gold nanoparticles in H[AuCl4]/chitosan solutions starts with hydrolysis of chitosan catalyzed by Au(III). The products of chitosan hydrolysis rather than chitosan itself act as the main reducing species. According to (13)C and (1)H NMR spectroscopy data, chitosan/Au(0) composites contain chitosan with reduced molecular weight and acetylation degree, whereas water-soluble by-products consist of chitosan oligomers with higher acetylation degree, derivatives of glucosamine acids, and formate ion. Chitosan degradation has significantly contributed to the decrease of its efficiency as a gold nanoparticles stabilizer. The gold particle size increased from 6.9 nm to 16.2 nm, when Au(III)/chitosan molar ratio changed from 1:80 to 1:10.

  4. Data summary report for fission product release test VI-6

    SciTech Connect

    Osborne, M.F.; Lorenz, R.A.; Travis, J.R.; Webster, C.S.; Collins, J.L.

    1994-03-01

    Test VI-6 was the sixth test in the VI series conducted in the vertical furnace. The fuel specimen was a 15.2-cm-long section of a fuel rod from the BR3 reactor in Belgium. The fuel had experienced a burnup of {approximately}42 MWd/kg, with inert gas release during irradiation of {approximately}2%. The fuel specimen was heated in an induction furnace at 2300 K for 60 min, initially in hydrogen, then in a steam atmosphere. The released fission products were collected in three sequentially operated collection trains designed to facilitate sampling and analysis. The fission product inventories in the fuel were measured directly by gamma-ray spectrometry, where possible, and were calculated by ORIGEN2. Integral releases were 75% for {sup 85}Kr, 67% for {sup 129}I, 64% for {sup 125}Sb, 80% for both {sup 134}Cs and {sup 137}Cs, 14% for {sup 154}Eu, 63% for Te, 32% for Ba, 13% for Mo, and 5.8% for Sr. Of the totals released from the fuel, 43% of the Cs, 32% of the Sb, and 98% of the Eu were deposited in the outlet end of the furnace. During the heatup in hydrogen, the Zircaloy cladding melted, ran down, and reacted with some of the UO{sub 2} and fission products, especially Te and Sb. The total mass released from the furnace to the collection system, including fission products, fuel, and structural materials, was 0.57 g, almost equally divided between thermal gradient tubes and filters. The release behaviors for the most volatile elements, Kr and Cs, were in good agreement with the ORNL Diffusion Model.

  5. Flow tests of the Willis Hulin Well. Volume III. Final report for the period October 1985--October 1990

    SciTech Connect

    Randolph, P.L.; Hayden, C.G.; Rogers, L.A.

    1992-02-01

    The initial flow test of the Hulin well was done to obtain brine and gas samples and to get a first measure of the reservoir properties. The 20,602 to 20,690-foot interval was perforated and tested in two short-term draw-down and buildup tests. This zone had an initial pressure of 17,308 psia and temperature of 339 F. The total dissolved solids of 207,000 mg/L (mostly sodium chloride) is higher than for previously tested Gulf Coast geopressured-geothermal wells. The gas content in the brine of 31 to 32 SCF/STB indicates that the brine is at or near saturation with natural gas. The permeability, as deduced from the draw-down and buildup tests, is 13 md for the lower 80-foot-thick sand member. The duration of the tests was too short to determine the lateral extent of the reservoir; but declining measured values for static bottomhole pressure prior to each flow test suggests a relatively small reservoir. When the uppermost interval in the zone of interest (20,220 to 20,260 feet) was perforated such that flow from this zone would commingle with flow from the lower zone, little to no free gas was observed. It had been speculated before the test that there might be free gas in this upper zone. These speculations were generally deduced from logs after assuming the formation contained brine that had a salinity between 70,000 and 100,000 mg/L. The actual salinity was more than twice that number. it is now apparent that the amount of free gas, if any, is too small to make a significant contribution to production in a short-term test. This does not preclude the possibility of mobilization of gas by higher drawdown or coning down from an offsetting gas cap in one or more of the sand members. However, there was no evidence that this was occurring in this test. No measurements of the reservoir parameters, such as permeability, were made for the shallowest interval tested. But substantially lower drawdown for the commingled zones suggests either higher permeability or lower skin

  6. Three new europium(III) methanetriacetate metal-organic frameworks: the influence of synthesis on the product topology.

    PubMed

    Cañadillas-Delgado, Laura; Fabelo, Oscar; Pasán, Jorge; Déniz, Mariadel; Martínez-Benito, Carla; Díaz-Gallifa, Pau; Martín, Tomás; Ruiz-Pérez, Catalina

    2014-02-01

    Three new metal-organic framework structures containing Eu(III) and the little explored methanetriacetate (C7H7O6(3-), mta(3-)) ligand have been synthesized. Gel synthesis yields a two-dimensional framework with the formula [Eu(mta)(H2O)3]n·2nH2O, (I), while two polymorphs of the three-dimensional framework material [Eu(mta)(H2O)]n·nH2O, (II) and (III), are obtained through hydrothermal synthesis at either 423 or 443 K. Compounds (I) and (II) are isomorphous with previously reported Gd(III) compounds, but compound (III) constitutes a new phase. Compound (I) can be described in terms of dinuclear [Eu2(H2O)4](6+) units bonded through mta(3-) ligands to form a two-dimensional framework with topology corresponding to a (6,3)-connected binodal (4(3))(4(6)6(6)8(3))-kgd net, where the dinuclear [Eu2(H2O)4](6+) units are considered as a single node. Compounds (II) and (III) have distinct three-dimensional topologies, namely a (4(12)6(3))(4(9)6(6))-nia net for (II) and a (4(10)6(5))(4(11)6(4))-K2O2; 36641 net for (III). The crystal density of (III) is greater than that of (II), consistent with the increase of temperature, and thereby autogeneous pressure, in the hydrothermal synthesis.

  7. Simple and Inexpensive Computer Interface to a Durrum Stopped-Flow Apparatus Tested Using the Iron (III)--Thiocyanate Reaction

    ERIC Educational Resources Information Center

    Hoag, Craig M.

    2005-01-01

    A simple Vernier software and Technology LabPro unit was used to interface a computer with a Durrum model 110 stopped-flow apparatus using the iron (III)--thiocyanate reaction. The software can readily be used to retrieve that data from the stopped-flow apparatus using one probe to measure the voltage and a second probe to trigger the data…

  8. An optical instrument to test pesticide residues in agricultural products

    NASA Astrophysics Data System (ADS)

    Qiu, Zhengjun; Zheng, Wenzhong; Fang, Hui; He, Yong

    2005-10-01

    Pesticide is one of the indispensability materials in modern agricultural management, however the excessive use of pesticides has threatened the ecological environment and people's health. This paper introduced an optical instrument to test the pesticide residues in agricultural products based on the inhibition rate of organophosphates against acrtyl-cholinesterase (AchE). The instrument consists mainly of a solid light source with 410nm wavelength, a sampling container, an optical sensor, a temperature sensor, and a MCU based data acquisition board. The light illuminated through the liquid in the sampling container, and the absorptivity was determined by the amount of the pesticide residues in the liquid. This paper involves the design of optical testing system, the data acquisition and calibration of the optical sensor, the design of microcontroller-based electrical board. Tests were done to reveal the affection of temperature and reacting time on AchE, to establish the relationship between the amount of methamidophos and dichlorvos with AchE. The results showed that the absorption rate was related to the pesticide residues and it could be concluded that the pesticide residues exceeded the normal level when the inhibition rate was over 50 percent. The instrument has potential application in vegetable markets.

  9. Interleukin-8 (IL-8) over-production and autocrine cell activation are key factors in monomethylarsonous acid [MMA(III)]-induced malignant transformation of urothelial cells

    SciTech Connect

    Escudero-Lourdes, C.; Wu, T.; Camarillo, J.M.; Gandolfi, A.J.

    2012-01-01

    The association between chronic human exposure to arsenicals and bladder cancer development is well recognized; however, the underlying molecular mechanisms have not been fully determined. We propose that inflammatory responses can play a pathogenic role in arsenic-related bladder carcinogenesis. In previous studies, it was demonstrated that chronic exposure to 50 nM monomethylarsenous acid [MMA(III)] leads to malignant transformation of an immortalized model of urothelial cells (UROtsa), with only 3 mo of exposure necessary to trigger the transformation-related changes. In the three-month window of exposure, the cells over-expressed pro-inflammatory cytokines (IL-1β, IL-6 and IL-8), consistent with the sustained activation of NFKβ and AP1/c-jun, ERK2, and STAT3. IL-8 was over-expressed within hours after exposure to MMA(III), and sustained over-expression was observed during chronic exposure. In this study, we profiled IL-8 expression in UROtsa cells exposed to 50 nM MMA(III) for 1 to 5 mo. IL-8 expression was increased mainly in cells after 3 mo MMA(III) exposure, and its production was also found increased in tumors derived from these cells after heterotransplantation in SCID mice. UROtsa cells do express both receptors, CXCR1 and CXCR2, suggesting that autocrine cell activation could be important in cell transformation. Supporting this observation and consistent with IL-8 over-expression, CXCR1 internalization was significantly increased after three months of exposure to MMA(III). The expression of MMP-9, cyclin D1, bcl-2, and VGEF was significantly increased in cells exposed to MMA(III) for 3 mo, but these mitogen-activated kinases were significantly decreased after IL-8 gene silencing, together with a decrease in cell proliferation rate and in anchorage-independent colony formation. These results suggest a relevant role of IL-8 in MMA(III)-induced UROtsa cell transformation. -- Highlights: ► IL-8 is over-expressed in human MMA(III)-exposed urothelial

  10. Validation of Global EO Biophysical Products at JECAM Test Site in Ukraine

    NASA Astrophysics Data System (ADS)

    Skakun, Sergii; Kussul, Nataliia; Kravchenko, Oleksiy; Basarab, Ruslan; Ostapenko, Vadym; Yailymov, Bohdan; Shelestov, Andrii; Kolotii, Andrii; Mironov, Andrii

    Efficient global agriculture monitoring requires appropriate validation of Earth observation (EO) products for different regions and cropping system. This problem is addressed within the Joint Experiment of Crop Assessment and Monitoring (JECAM) initiative which aims to develop monitoring and reporting protocols and best practices for a variety of global agricultural systems. Ukraine is actively involved into JECAM, and a JECAM Ukraine test site was officially established in 2011. The following problems are being solved within JECAM Ukraine: (i) crop identification and crop area estimation [1]; (ii) crop yield forecasting [2]; (iii) EO products validation. The following case study regions were selected for these purposes: (i) the whole Kyiv oblast (28,000 sq. km) indented for crop mapping and acreage estimation; (ii) intensive observation sub-site in Pshenichne which is a research farm from the National University of Life and Environmental Sciences of Ukraine and indented for crop biophysical parameters estimation; (iii) Lviv region for rape-seed identification and crop rotation control; (iv) Crimea region for crop damage assessment due to droughts, and illegial field detection. In 2013, Ukrainian JECAM test site was selected as one of the “Champion User” for the ESA Sentinel-2 for Agriculture project. The test site was observed with SPOT-4 and RapidEye satellites every 5 days. The collected images are then used to simulate Sentinel-2 images for agriculture purposes. JECAM Ukraine is responsible for collecting ground observation data for validation purposes, and is involved in providing user requirements for Sentinel-2 agriculture related products. In particular, three field campaigns to characterize the vegetation biophysical parameters at the Pshenichne test site were carried out: First campaign - 14th to 17th of May 2013; second campaign - 12th to 15th of June 2013; third campaign - 14th to 17th of July 2013. Digital Hemispheric Photographs (DHP) images were

  11. Three new europium(III) methanetriacetate metal-organic frameworks: the influence of synthesis on the product topology.

    PubMed

    Cañadillas-Delgado, Laura; Fabelo, Oscar; Pasán, Jorge; Déniz, Mariadel; Martínez-Benito, Carla; Díaz-Gallifa, Pau; Martín, Tomás; Ruiz-Pérez, Catalina

    2014-02-01

    Three new metal-organic framework structures containing Eu(III) and the little explored methanetriacetate (C7H7O6(3-), mta(3-)) ligand have been synthesized. Gel synthesis yields a two-dimensional framework with the formula [Eu(mta)(H2O)3]n·2nH2O, (I), while two polymorphs of the three-dimensional framework material [Eu(mta)(H2O)]n·nH2O, (II) and (III), are obtained through hydrothermal synthesis at either 423 or 443 K. Compounds (I) and (II) are isomorphous with previously reported Gd(III) compounds, but compound (III) constitutes a new phase. Compound (I) can be described in terms of dinuclear [Eu2(H2O)4](6+) units bonded through mta(3-) ligands to form a two-dimensional framework with topology corresponding to a (6,3)-connected binodal (4(3))(4(6)6(6)8(3))-kgd net, where the dinuclear [Eu2(H2O)4](6+) units are considered as a single node. Compounds (II) and (III) have distinct three-dimensional topologies, namely a (4(12)6(3))(4(9)6(6))-nia net for (II) and a (4(10)6(5))(4(11)6(4))-K2O2; 36641 net for (III). The crystal density of (III) is greater than that of (II), consistent with the increase of temperature, and thereby autogeneous pressure, in the hydrothermal synthesis. PMID:24441124

  12. 46 CFR 160.135-15 - Production inspections, tests, quality control, and conformance of lifeboats.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 6 2013-10-01 2013-10-01 false Production inspections, tests, quality control, and... Lifeboats (SOLAS) § 160.135-15 Production inspections, tests, quality control, and conformance of lifeboats... appropriate, inspections, tests, and oversight required by this section. Production inspections and tests...

  13. 30 CFR 250.1151 - How often must I conduct well production tests?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false How often must I conduct well production tests... Requirements Well Tests and Surveys § 250.1151 How often must I conduct well production tests? (a) You must conduct well production tests as shown in the following table: You must conduct: And you must submit...

  14. Prostaglandin E2 and F2 alpha inhibit growth of human gastric carcinoma cell line KATO III with simultaneous stimulation of cyclic AMP production.

    PubMed

    Nakamura, A; Chiba, T; Yamatani, T; Yamaguchi, A; Inui, T; Morishita, T; Kadowaki, S; Fujita, T

    1989-01-01

    The effects of prostaglandins (PGs) on the growth of human gastric carcinoma cell line KATO III were investigated. PGE2 as well as PGF2 alpha significantly and dose-dependently inhibited the growth of this gastric carcinoma cell line (PGE2 greater than PGF2 alpha). This inhibition of cell growth by the PGs was associated with the increase in cyclic AMP production (PGE2 greater than PGF2 alpha), whereas inositol-phospholipid turnover was not affected by either PGE2 or PGF2 alpha as assessed by the formation of 3H-inositol phosphates. Furthermore, the proliferation of these gastric carcinoma cells was also suppressed by the administration of forskolin as well as of dibutyryl cyclic AMP. These results suggest that PGE2 and PGF2 alpha inhibit the growth of cultured human gastric carcinoma cells KATO III via stimulation of cyclic AMP production. PMID:2536452

  15. (Quality control and nondestructive test procedures for welded products)

    SciTech Connect

    Childress, C.E.

    1990-11-09

    The International Institute of Welding is composed of some 600 technical experts from 36 countries. These individuals are divided by talent and personal interest into fifteen separate groups called Commissions, each with its own charter and goals. The title, and by inference the charter, of Commission V is : Quality Control and Quality Assurance of Welded Products. In pursuit of its charter Commission V has several subcommissions engaged in the development of drafts, procedures, and standards. Those documents subsequently considered suitable may be submitted to the International Organization for Standards (ISO), an organization similar to the American Society for Testing Materials, for acceptance as international standards. All ISO Procedures and standards which have been in effect for five years must undergo review by the initiating body. The results from review of five-year-old standards and procedures and the discussion of other documents proposed for international publication are presented.

  16. Data summary report for fission product release Test VI-7

    SciTech Connect

    Osborne, M.F.; Lorentz, R.A.; Travis, J.R.; Collins, J.L.; Webster, C.S.

    1995-05-01

    Test VI-7 was the final test in the VI series conducted in the vertical furnace. The fuel specimen was a 15.2-cm-long section of a fuel rod from the Monticello boiling water reactor (BWR). The fuel had experienced a burnup of {approximately}-40 Mwd/kg U. It was heated in an induction furnace for successive 20-min periods at 2000 and 2300 K in a moist air-helium atmosphere. Integral releases were 69% for {sup 85}Kr, 52% for {sup 125}Sb, 71% for both {sup 134}Cs and {sup 137}Cs, and 0.04% for {sup 154}Eu. For the non-gamma-emitting species, release values for 42% for I, 4.1% for Ba, 5.3% for Mo, and 1.2% for Sr were determined. The total mass released from the furnace to the collection system, including fission products, fuel, and structural materials, was 0.89 g, with 37% being collected on the thermal gradient tubes and 63% downstream on filters. Posttest examination of the fuel specimen indicated that most of the cladding was completely oxidized to ZrO{sub 2}, but that oxidation was not quite complete at the upper end. The release behaviors for the most volatile elements, Kr and Cs, were in good agreement with the ORNL-Booth Model.

  17. Oxidation of indole-3-acetic acid by peroxidase: involvement of reduced peroxidase and compound III with superoxide as a product.

    PubMed

    Smith, A M; Morrison, W L; Milham, P J

    1982-08-31

    Kinetic and spectral data establish that peroxidase may oxidize indole-3-acetic acid by either of two pathways depending on the enzyme/substrate ratio. When relatively low enzyme/substrate ratios are employed, the oxidation proceeds through a reduced peroxidase in equilibrium compound III shuttle. Conversely, peroxidase operates through the conventionally accepted pathway involving native enzyme and compounds I and II only when high enzyme/substrate ratios are used. Compound III, a specific oxidase, constitutes the dominant steady-state form of peroxidase when the reduced peroxidase in equilibrium compound III shuttle is operational. Activation of this shuttle also produces a flux of superoxide anion radical at the expense of molecular oxygen. Thus, important biological consequences may follow activation of this shuttle under physiological conditions.

  18. Two Translation Products of Yersinia yscQ Assemble To Form a Complex Essential to Type III Secretion

    SciTech Connect

    Bzymek, Krzysztof P.; Hamaoka, Brent Y.; Ghosh, Partho

    2012-07-11

    The bacterial flagellar C-ring is composed of two essential proteins, FliM and FliN. The smaller protein, FliN, is similar to the C-terminus of the larger protein, FliM, both being composed of SpoA domains. While bacterial type III secretion (T3S) systems encode many proteins in common with the flagellum, they mostly have a single protein in place of FliM and FliN. This protein resembles FliM at its N-terminus and is as large as FliM but is more like FliN at its C-terminal SpoA domain. We have discovered that a FliN-sized cognate indeed exists in the Yersinia T3S system to accompany the FliM-sized cognate. The FliN-sized cognate, YscQ-C, is the product of an internal translation initiation site within the locus encoding the FliM-sized cognate YscQ. Both intact YscQ and YscQ-C were found to be required for T3S, indicating that the internal translation initiation site, which is conserved in some but not all YscQ orthologs, is crucial for function. The crystal structure of YscQ-C revealed a SpoA domain that forms a highly intertwined, domain-swapped homodimer, similar to those observed in FliN and the YscQ ortholog HrcQ{sub B}. A single YscQ-C homodimer associated reversibly with a single molecule of intact YscQ, indicating conformational differences between the SpoA domains of intact YscQ and YscQ-C. A 'snap-back' mechanism suggested by the structure can account for this. The 1:2 YscQ-YscQ-C complex is a close mimic of the 1:4 FliM-FliN complex and the likely building block of the putative Yersinia T3S system C-ring.

  19. Validating NEXRAD MPE and Stage III precipitation products for uniform rainfall on the Upper Guadalupe River Basin of the Texas Hill Country

    NASA Astrophysics Data System (ADS)

    Wang, Xianwei; Xie, Hongjie; Sharif, Hatim; Zeitler, Jon

    2008-01-01

    SummaryThis study examines the performance of the Next Generation Weather Radar (NEXRAD) Multisensor Precipitation Estimator (MPE) and Stage III precipitation products, using a high-density rain gauge network located on the Upper Guadalupe River Basin of the Texas Hill Country. As point-area representativeness error of gauge rainfall is a major concern in assessment of radar rainfall estimation, this study develops a new method to automatically select uniform rainfall events based on coefficient of variation criterion of 3 by 3 radar cells. Only gauge observations of those uniform rainfall events are used as ground truth to evaluate radar rainfall estimation. This study proposes a new parameter probability of rain detection (POD) instead of the conditional probability of rain detection (CPOD) commonly used in previous studies to assess the capability that a radar or gauge detects rainfall. Results suggest that: (1) gauge observations of uniform rainfall better represent ground truth of a 4 × 4 km 2 radar cell than non-uniform rainfall; (2) the MPE has higher capability of rain detection than either gauge-only or Stage III; (3) the MPE has much higher linear correlation and lower mean relative difference with gauge measurements than the Stage III does; (4) the Stage III tends to overestimate precipitation (20%), but the MPE tends to underestimate (7%).

  20. Testing the soil production paradigm: Role of catchment-mean erosion rate in colluvial soil production

    NASA Astrophysics Data System (ADS)

    Foster, M.; Whipple, K. X.; Heimsath, A. M.

    2013-12-01

    Colluvial soil thickness is a fundamental characteristic of the critical zone, playing an essential role in hydrology, ecology, the action of biogeochemical cycles, and erosion and transport processes. Colluvial soil thickness reflects a balance between soil production (the conversion of rock to mobile regolith) and erosion. Further, well-established theory predicts that: (1) mean soil thickness decreases with increasing catchment-mean erosion rate and (2) that soil-mantled landscapes give way to rocky ones when catchment-mean erosion rate exceeds the climate- and lithology-controlled maximum soil production rate that occurs on bare-rock surfaces or under a thin soil cover. This critical erosion rate is thus expected to be associated with a sudden and profound change in hydrology, ecology, biogeochemical processes, and erosion/sediment transport processes. Despite the pervasive acceptance of this idea, it has never been systematically tested and even casual observations reveal that it may be flawed. Indeed, a global compilation of available soil production rate constants suggests that erosion rate is the strongest control, implying that well-established theory is fundamentally incorrect. Although the efficiency of soil production is thought to be set by climate and lithology alone, recent work suggests that it increases in concert with catchment-mean erosion rates and associated changes in process dominance and landscape morphology; existing models may exaggerate changes in critical-zone properties in response to tectonic uplift. Three fundamental observations support this claim: (1) observed soil thicknesses vary little across 2 orders of magnitude variation in erosion rate in published soil-production studies; (2) soil cover persists in landscapes eroding at well above the putative soil-production "speed limit"; and (3) published estimates of the rate constant in the exponential soil-production function increases linearly with catchment-mean erosion rate

  1. Chemical Characterization and Reactivity Testing of Fuel-Oxidizer Reaction Product (Test Report)

    NASA Technical Reports Server (NTRS)

    1996-01-01

    The product of incomplete reaction of monomethylhydrazine (MMH) and nitrogen tetroxide (NTO) propellants, or fuel-oxidizer reaction product (FORP), has been hypothesized as a contributory cause of an anomaly which occurred in the chamber pressure (PC) transducer tube on the Reaction Control Subsystem (RCS) aft thruster 467 on flight STS-51. A small hole was found in the titanium-alloy PC tube at the first bend below the pressure transducer. It was surmised that the hole may have been caused by heat and pressure resulting from ignition of FORP. The NASA Johnson Space Center (JSC) White Sands Test Facility (WSTF) was requested to define the chemical characteristics of FORP, characterize its reactivity, and simulate the events in a controlled environment which may have lead to the Pc-tube failure. Samples of FORP were obtained from the gas-phase reaction of MMH with NTO under laboratory conditions, the pulsed firings of RCS thrusters with modified PC tubes using varied oxidizer or fuel lead times, and the nominal RCS thruster firings at WSTF and Kaiser-Marquardt. Fourier transform infrared spectroscopy (FTIR), differential scanning calorimetry (DSC), accelerating rate calorimetry (ARC), ion chromatography (IC), inductively coupled plasma (ICP) spectrometry, thermogravimetric analysis (TGA) coupled to FTIR (TGA/FTIR), and mechanical impact testing were used to qualitatively and quantitatively characterize the chemical, thermal, and ignition properties of FORP. These studies showed that the composition of FORP is variable but falls within a limited range of compositions that depends on the fuel loxidizer ratio at the time of formation, composition of the post-formation atmosphere (reducing or oxidizing), and reaction or postreaction temperature. A typical composition contains methylhydrazinium nitrate (MMHN), ammonium nitrate (AN), methylammonium nitrate (MAN), and trace amounts of hydrazinium nitrate and 1,1-dimethylhydrazinium nitrate. The thermal decomposition

  2. Role of DNA-Dependent RNA Polymerases II and III in Transcription of the Adenovirus Genome Late in Productive Infection

    PubMed Central

    Weinmann, Roberto; Raskas, Heschel J.; Roeder, Robert G.

    1974-01-01

    DNA-dependent RNA polymerases I, II, and III were isolated and partially purified from KB (human) cells 18 hr after infection with adenovirus 2. As reported previously for the enzymes from other animal cells, RNA polymerase II was completely sensitive to low concentrations of α-amanitin (50% inhibition at 0.02 μg/ml), RNA polymerase III was completely sensitive to high concentrations of α-amanitin (50% inhibition at 20 μg/ml) and RNA polymerase I was totally resistant to concentrations of α-amanitin less than or equal to 200 μg/ml. RNA synthesis by the endogenous RNA polymerase activities in nuclei isolated from infected cells was completely sensitive to α-amanitin, thus suggesting that RNA polymerase I is not involved in viral DNA transcription even though it is present in these cells. The α-amanitin inhibition curve was biphasic and showed inflection points at about 0.02 and 20 μg/ml, suggesting the participation of both RNA polymerases II and III in the synthesis of RNA in these nuclei. Furthermore, at least a large fraction of the synthesis of the nuclear precursors to viral mRNA, monitored by hybridization to viral DNA, showed the same sensitivity to α-amanitin as did RNA polymerase II; and the synthesis of both viral 5.5S RNA and (presumably cellular) 5S RNA in the isolated nuclei exhibited the same sensitivity to α-amanitin as did purified RNA polymerase III. Thus, these data provide strong supporting evidence for previous studies which suggested the involvement of an RNA polymerase II in transcription of the adenovirus genome and demonstrate the role of an RNA polymerase III activity in the synthesis of viral 5.5S RNA and cellular 5S RNA. PMID:4530313

  3. Implementing and testing ATM in a production LAN

    SciTech Connect

    Naegle, J.; Testi, N.; Tolendino, L.; Zepper, J.

    1995-06-01

    Asynchronous Transfer Mode (ATM) technology is currently receiving extensive attention in the computer networking arena. Many experts predict that ATM will be the future networking technology for both the Local Area Network (LAN) and the Wide Area Network (WAN). This paper presents the results of a collaboration between Sandia National Laboratories` Advanced Networking Department and Engineering Sciences Center to study the implementation of ATM in one of Sandia`s most heavily loaded production networks. The network consists of over 120 Sun Sparc 10s and 20s, two SparcCenter 2000s, a 12 node parallel IBM SP-2, and several other miscellaneous high-end workstations. The existing network was first characterized through extensive traffic measurements to better understand the capabilities and limitations of the existing network technologies and to provide a baseline for comparison to an ATM network. This characterization was used to select a subset of the network elements which would benefit most from conversion to the ATM technology. This subset was then converted to equipment based on the latest ATM standards. With direct OC-3c (155 Mbps) host connections for the workstations and the file and compute servers, we demonstrated as much as 122 Mbps throughput (memory-to-memory TCP/IP transfers) between endpoints. Flow control in the classical many-to-one client server environment was also investigated. Throughout all of our tests, the interaction of the user applications with the network technologies was documented and possible improvements were tested. The performance and reliability of the ATM network was compared to the original network to determine the benefits and liabilities of the ATM technology.

  4. 46 CFR 160.135-15 - Production inspections, tests, quality control, and conformance of lifeboats.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... lifeboats or their component parts and materials, or records are retained to meet the requirements of... manufacturer is satisfactory; (ii) Witnessing tests; or (iii) Taking samples of parts or materials for... CFR 159.007-13. The manufacturer must keep records of all items listed in this section for at least...

  5. 30 CFR 250.804 - Production safety-system testing and records.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... (excluding electronic pressure transmitters and level sensors) must be tested at least once each calendar... LSL controls, (iii) All automatic inlet SDV's which are actuated by a sensor on a vessel or compressor, and (iv) All SDV's in liquid discharge lines and actuated by vessel low-level sensors. (4)...

  6. 30 CFR 250.804 - Production safety-system testing and records.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... (excluding electronic pressure transmitters and level sensors) must be tested at least once each calendar... LSL controls, (iii) All automatic inlet SDV's which are actuated by a sensor on a vessel or compressor, and (iv) All SDV's in liquid discharge lines and actuated by vessel low-level sensors. (4)...

  7. Rapid and sensitive lateral flow immunoassay method for determining alpha fetoprotein in serum using europium (III) chelate microparticles-based lateral flow test strips.

    PubMed

    Liang, Rong-Liang; Xu, Xu-Ping; Liu, Tian-Cai; Zhou, Jian-Wei; Wang, Xian-Guo; Ren, Zhi-Qi; Hao, Fen; Wu, Ying-Song

    2015-09-01

    Alpha-fetoprotein (AFP), a primary marker for many diseases including various cancers, is important in clinical tumor diagnosis and antenatal screening. Most immunoassays provide high sensitivity and accuracy for determining AFP, but they are expensive, often complex, time-consuming procedures. A simple and rapid point-of-care system that integrates Eu (III) chelate microparticles with lateral flow immunoassay (LFIA) has been developed to determine AFP in serum with an assay time of 15 min. The approach is based on a sandwich immunoassay performed on lateral flow test strips. A fluorescence strip reader was used to measure the fluorescence peak heights of the test line (HT) and the control line (HC); the HT/HC ratio was used for quantitation. The Eu (III) chelate microparticles-based LFIA assay exhibited a wide linear range (1.0-1000 IU mL(-1)) for AFP with a low limit of detection (0.1 IU mL(-1)) based on 5ul of serum. Satisfactory specificity and accuracy were demonstrated and the intra- and inter-assay coefficients of variation (CV) for AFP were both <10%. Furthermore, in the analysis of human serum samples, excellent correlation (n = 284, r = 0.9860, p < 0.0001) was obtained between the proposed method and a commercially available CLIA kit. Results indicated that the Eu (III) chelate microparticles-based LFIA system provided a rapid, sensitive and reliable method for determining AFP in serum, indicating that it would be suitable for development in point-of-care testing.

  8. Rapid and sensitive lateral flow immunoassay method for determining alpha fetoprotein in serum using europium (III) chelate microparticles-based lateral flow test strips.

    PubMed

    Liang, Rong-Liang; Xu, Xu-Ping; Liu, Tian-Cai; Zhou, Jian-Wei; Wang, Xian-Guo; Ren, Zhi-Qi; Hao, Fen; Wu, Ying-Song

    2015-09-01

    Alpha-fetoprotein (AFP), a primary marker for many diseases including various cancers, is important in clinical tumor diagnosis and antenatal screening. Most immunoassays provide high sensitivity and accuracy for determining AFP, but they are expensive, often complex, time-consuming procedures. A simple and rapid point-of-care system that integrates Eu (III) chelate microparticles with lateral flow immunoassay (LFIA) has been developed to determine AFP in serum with an assay time of 15 min. The approach is based on a sandwich immunoassay performed on lateral flow test strips. A fluorescence strip reader was used to measure the fluorescence peak heights of the test line (HT) and the control line (HC); the HT/HC ratio was used for quantitation. The Eu (III) chelate microparticles-based LFIA assay exhibited a wide linear range (1.0-1000 IU mL(-1)) for AFP with a low limit of detection (0.1 IU mL(-1)) based on 5ul of serum. Satisfactory specificity and accuracy were demonstrated and the intra- and inter-assay coefficients of variation (CV) for AFP were both <10%. Furthermore, in the analysis of human serum samples, excellent correlation (n = 284, r = 0.9860, p < 0.0001) was obtained between the proposed method and a commercially available CLIA kit. Results indicated that the Eu (III) chelate microparticles-based LFIA system provided a rapid, sensitive and reliable method for determining AFP in serum, indicating that it would be suitable for development in point-of-care testing. PMID:26388387

  9. Tests of Environmental Effects on SN Ia Production

    NASA Astrophysics Data System (ADS)

    Strolger, Louis-Gregory; van Dyk, Schuyler; Wolff, Schuyler; Campbell, Lachlan; Sadler, Suzanna; Pease, April

    2011-02-01

    The largely unknown type Ia supernova mechanism remains one of the largest sources of possible systematic uncertainty in achieving precise measures of dark energy. The host galaxy environments of SNe Ia provide our best opportunity for constraining the mechanism(s) of the SN Ia progenitor system, i.e., the stars involved, the incubation times, and the sensitivity of SNe Ia to changes in the local gas-phase metallicity. The latter can affect the luminosity of the resultant Ia event, and possibly the success in ultimately yielding a SN Ia event. We seek to solidify possible environmental trends in SN Ia rates from direct measures of host galaxy properties, using the sample collected by the Nearby Galaxies Supernova Search project. This study will uncover which has the greatest influence on SN Ia production efficiency: parent population age, rate of star-formation, or metallicity. Here, we propose to continue our analysis using the Mayall 4m + RCSP to obtain broad SEDs, R_23 metallicities, and star formation rates for 18 of the 25 remaining host galaxies (all z≤0.15) from the NGSS sample (20 targets were obtained in the 2010 semesters). These data will be combined with the remaining sample to be completed in the 2011B semester. The sample will provide a validity test of the mostly indirect trends being established for SNe Ia from the LOSS, SDSS, SNfactory and other surveys, and ultimately steer future investigations towards more precise SN Ia cosmology.

  10. Tests of Environmental Effects on Type Ia Supernova Production

    NASA Astrophysics Data System (ADS)

    Sadler, Suzanna M.; Strolger, L.; Wolff, S.

    2011-01-01

    The host galaxy environments of type Ia supernovae (SNe Ia) provide our best opportunity for constraining the mechanism(s) of the SN Ia progenitor system, i.e., the stars involved, the incubation times, and the sensitivity of SNe Ia to changes in the local gas-phase metallicity. The latter can affect the luminosity of the resultant event, and possibly the success in ultimately yielding a SN Ia. We seek to solidify possible environmental trends in SN Ia rates from direct measures of host galaxy properties, using the sample collected by the Nearby Galaxies Supernova Search project. This study will uncover which has the greatest influence on SN Ia production efficiency: parent population age, rate of star-formation, or metallicity. Here, we will show some preliminary results from SSP model fitting (of age and [Fe/H]) to a selection of hosts obtained thus far from this study. The complete sample will provide a validity test of the mostly indirect trends being established for SNe Ia from the LOSS, SDSS, SNfactory and other surveys, and may ultimately steer future investigations towards more precise SN Ia cosmology.

  11. Tests of Environmental Effects on SN Ia Production

    NASA Astrophysics Data System (ADS)

    Strolger, Louis-Gregory; Wolff, Schuyler; Pease, April

    2010-02-01

    The largely unknown type Ia supernova (SN Ia) mechanism remains one of the largest sources of possible systematic uncertainty in achieving precise measures of dark energy. The host galaxy environments of SNe Ia provide our best opportunity for constraining the mechanism(s) of the SN Ia progenitor system, i.e., the stars involved, the incubation times, and the sensitivity of SNe Ia to changes in the local gas-phase metallicity. The latter can affect the luminosity of the resultant Ia event, and possibly the success in ultimately yielding a SN Ia event. We seek to solidify possible environmental trends in SN Ia rates from direct measures of host galaxy properties, using the sample collected by the Nearby Galaxies Supernova Search (NGSS) project. The purpose of this study is to uncover which has the greatest influence on SN Ia production efficiency: parent population age, rate of star- formation, or metallicity. Here, we propose to begin our analysis using any of NOAO-access 4m + spectrograph to obtain broad SEDs, R_23 metallicities, and star formation rates for 14 of the ~30 host galaxies (all z⪉0.1) from the NGSS sample. These data will be combined with the remaining sample to be sought in the 2010B and future semesters. The sample will provide a validity test of the mostly indirect trends being established for SNe Ia from the SNfactory, SDSS, and other surveys, and ultimately steer future investigations towards more precise SN Ia cosmology.

  12. Application for a Permit to Operate a Class III Solid Waste Disposal Site at the Nevada Test Site Area 5 Asbestiform Low-Level Solid Waste Disposal Site

    SciTech Connect

    NSTec Environmental Programs

    2010-09-14

    The NTS solid waste disposal sites must be permitted by the state of Nevada Solid Waste Management Authority (SWMA). The SWMA for the NTS is the Nevada Division of Environmental Protection, Bureau of Federal Facilities (NDEP/BFF). The U.S. Department of Energy's National Nuclear Security Administration Nevada Site Office (NNSA/NSO) as land manager (owner), and National Security Technologies (NSTec), as operator, will store, collect, process, and dispose all solid waste by means that do not create a health hazard, a public nuisance, or cause impairment of the environment. NTS disposal sites will not be included in the Nye County Solid Waste Management Plan. The NTS is located approximately 105 kilometers (km) (65 miles [mi]) northwest of Las Vegas, Nevada (Figure 1). The U.S. Department of Energy (DOE) is the federal lands management authority for the NTS, and NSTec is the Management and Operations contractor. Access on and off the NTS is tightly controlled, restricted, and guarded on a 24-hour basis. The NTS has signs posted along its entire perimeter. NSTec is the operator of all solid waste disposal sites on the NTS. The Area 5 RWMS is the location of the permitted facility for the Solid Waste Disposal Site (SWDS). The Area 5 RWMS is located near the eastern edge of the NTS (Figure 2), approximately 26 km (16 mi) north of Mercury, Nevada. The Area 5 RWMS is used for the disposal of low-level waste (LLW) and mixed low-level waste. Many areas surrounding the RWMS have been used in conducting nuclear tests. A Notice of Intent to operate the disposal site as a Class III site was submitted to the state of Nevada on January 28, 1994, and was acknowledged as being received in a letter to the NNSA/NSO on August 30, 1994. Interim approval to operate a Class III SWDS for regulated asbestiform low-level waste (ALLW) was authorized on August 12, 1996 (in letter from Paul Liebendorfer to Runore Wycoff), with operations to be conducted in accordance with the ''Management Plan

  13. Fe(III) doped and grafted PbTiO{sub 3} film photocathode with enhanced photoactivity for hydrogen production

    SciTech Connect

    Hu, Yuxiang; Dong, Wen; Zheng, Fengang; Fang, Liang; Shen, Mingrong

    2014-08-25

    The photoelectrochemical activity of the PbTiO{sub 3} film photocathode deposited on indium tin oxide-coated quartz substrate was significantly improved through modifying the film surface by both the Fe(III) doping and grafting. Doping the PbTiO{sub 3} with Fe(III) ions narrows its band gap thus increases the visible light utilization, while the surface-grafted Fe(III) ions on the doped PbTiO{sub 3} surface are helpful to improve the charge transfer on the photocathode/electrolyte interface. Consequently, the photocurrent was increased from 38 μA/cm{sup 2} to 220 μA/cm{sup 2} under the irradiation of 100 mW/cm{sup 2} Xe lamp by using 0.1M Na{sub 2}SO{sub 4} as an electrolyte and zero-potential versus saturated calomel as a reference electrode. The corresponding increase in open circuit voltage was 0.95–1.11 V.

  14. Recent Performance Testing Results Using the 3-element Production Test Array for the Allen Telescope Array

    NASA Astrophysics Data System (ADS)

    Tarter, J. C.; Blitz, L.; ATA 25 person Team; Paul G. Allen Foundation Collaboration

    2002-12-01

    The Allen Telescope Array will consist of 350 fixed six-meter dishes at the Hat Creek Radio Observatory in northern California (land use permits pending). It is the first massively parallel array ever built. Where possible, components from consumer markets and mass-production manufacturing processes have been used to lower costs. The architecture of the array explicitly anticipates future growth as a result of "Moore's Law" improvements. There will be many novel features of this array including ultra-wideband instantaneous frequency coverage from 0.5 to 11 GHz, a very wide field of view (2.5 degrees across at 21 cm), miniaturized 80K cryogenics, full bandwidth analog data transmission from the antennas to the Myhrvold central processing facility, dynamic null-formation and tracking of satellite interferers, and continuous multi-user support for radio astronomical research and SETI explorations. Starting in July 2000, the technology development for this array has been a collaboration between the Paul G. Allen Foundation and the ATA team located at the SETI Institute and at the Radio Astronomy Laboratory at UC Berkeley. A rapid prototyping array (RPA) consisting of seven COTS antennas and room temperature L-band receivers was erected in Orinda, CA in March 2001. Thanks to strong and continuing support from Sun Microsystems, the RPA has provided an invaluable testbed for software development and evaluation of RFI mitigation schemes. An operational 3-element Production Test Array (PTA) has been implemented at Hat Creek Observatory over the last few months. The antennas, drives, monitor and control software, and frontend components are near-final versions to be manufactured for the full array. This poster provides performance data from the first few months of testing with the PTA. A final decision on commitment for construction is expected by April 1, 2003.

  15. Chromosome aberration and sister chromatid exchange tests in Chinese hamster ovary cells in vitro III: Results with 27 chemicals

    SciTech Connect

    Gulati, D.K. ); Witt, K.; Anderson, B.; Zeiger, E.; Shelby, M.D. )

    1989-01-01

    Twenty-seven chemicals previously tested in rodent carcinogenicity assays were tested for induction of chromosomal aberrations (ABS) and sister chromatid exchanges (SCE) in Chinese hamster ovary (CHO) cells as part of a larger analysis of the correlation between results of in vitro genetic toxicity assays and carcinogenicity bioassays. Chemicals were tested up to toxic doses with and without exogenous metabolic activation. Seventeen of the chemicals tested were carcinogens; only two of these were negative for both ABS and SCE. Of the eight noncarcinogens tested, four were negative for both endpoints and four gave a positive response for at least one endpoint. Of the remaining two chemicals, one, diallylphthalate, gave an equivocal response in the bioassay and a positive response in these CHO cell cytogenetics tests. The other chemical, 2,4-toluene diisocyanate, was tested for carcinogenicity as a mixture with the 2,6-isomer; the mixture was carinogenic, but the cytogenetic test results for the 2,4-isomer were negative. Experiments with unsynchronized CHO cells demonstrated that mean SCE frequency increased with increasing culture time, and this may have been a factor in the positive results obtained for five chemicals in the SCE test under conditions of delayed harvest.

  16. QCD tests in $p\\bar{p}$ collisions

    SciTech Connect

    Huth, John E.; Mangano, Michelangelo L.

    1993-02-01

    We review the status of QCD tests in high energy p-pbar collisions. Contents: i) Introduction ii) QCD in Hadronic Collisions iii) Jet Production iv) Heavy Flavour Production v) W and Z Production vi) Direct Photons.

  17. 49 CFR 178.33b-8 - Production tests.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... if the test container shall fail, the lot shall be rejected or ten additional containers may be... complete as intended for transportation. Should any of the ten containers thus tested fail, the entire...

  18. 46 CFR 160.171-25 - Production testing.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... this test if— (1) The measured buoyancy of the suit differs by more than 10% from the measured buoyancy of the suit tested for approval, (2) The adjusted buoyancy of the suit calculated using the...

  19. 46 CFR 160.171-25 - Production testing.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... this test if— (1) The measured buoyancy of the suit differs by more than 10% from the measured buoyancy of the suit tested for approval, (2) The adjusted buoyancy of the suit calculated using the...

  20. 46 CFR 160.171-25 - Production testing.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... this test if— (1) The measured buoyancy of the suit differs by more than 10% from the measured buoyancy of the suit tested for approval, (2) The adjusted buoyancy of the suit calculated using the...

  1. 46 CFR 160.171-25 - Production testing.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... this test if— (1) The measured buoyancy of the suit differs by more than 10% from the measured buoyancy of the suit tested for approval, (2) The adjusted buoyancy of the suit calculated using the...

  2. 46 CFR 161.012-13 - Production tests and inspections.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... ten lights from each lot of lights produced. Each lot must not exceed 1,000 lights. At least nine of the ten lights, when tested in accordance with the test described in § 161.012-11(c), must meet the... random sample of ten lights must be taken and tested. If less than nine of these lights meet the...

  3. 46 CFR 161.012-13 - Production tests and inspections.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... ten lights from each lot of lights produced. Each lot must not exceed 1,000 lights. At least nine of the ten lights, when tested in accordance with the test described in § 161.012-11(c), must meet the... random sample of ten lights must be taken and tested. If less than nine of these lights meet the...

  4. Finding Creative Potential on Intelligence Tests via Divergent Production

    ERIC Educational Resources Information Center

    Kaufman, James C.; Kaufman, Scott Barry; Lichtenberger, Elizabeth O.

    2011-01-01

    Assessing creative potential using a comprehensive battery of standardized tests requires a focus on "how" and "why" an individual responds in addition to "how well" they respond. Using the "intelligent testing" philosophy of focusing on the person being tested rather than the measure itself helps psychologists form a more complete picture of an…

  5. Subsurface interactions of Fe(II) with humic acid or landfill leachate do not control subsequent iron(III) (hydr)oxide production at the surface.

    PubMed

    Jackson, Alison; Gaffney, John W; Boult, Stephen

    2012-07-17

    At least 93% of Fe(II) remained free, as defined by ferrozine assay under anoxic conditions in the presence of humic acid (HA) and two simulated landfill leachates of different maturities. However, tangential flow ultrafiltration showed a weaker but more extensive interaction of Fe with organic carbon (OC); 90% of Fe associated with the less mature leachate. Despite the existence of this weak interaction under anoxic conditions, there was no difference in iron(III) (hydr)oxide production whether HA was added prior to or coincident with the oxidation of Fe(II) on exposure to oxic conditions. Under oxic conditions ferrozine showed that more Fe(II) bound to OC, up to 50% to HA. However, this occurs via oxidation of Fe(II) to Fe(III), which is bound and then thermally reduced. This affinity for Fe(III) and the ability to carry out thermal reduction both increase with the maturity of the OC. The rate at which ferrozine-defined free Fe(II) was lost on exposure to dissolved oxygen was also enhanced by the more mature OC, while it was slowed by acetogenic leachate. The slowing must be a consequence of the filtration-defined Fe(II)/OC interaction.

  6. Growian rotor blades: Production development, construction and test

    NASA Technical Reports Server (NTRS)

    Thiele, H. M.

    1984-01-01

    Development and construction of three 50 m rotor blades for a 3 MW wind turbine are described. A hybrid concept was chosen, i.e., a load carrying inflexible steel spar and a glass fiber reinforced plastic skin. A test blade was constructed and static loading tests, dynamic vibration tests and fatigue tests on critical welds as well as at the connection between spar and blade skin were performed. All test results show good accordance with calculated values, and were taken into consideration during the construction of two rotor blades.

  7. A prevalidation study on the in vitro skin irritation function test (SIFT) for prediction of acute skin irritation in vivo: results and evaluation of ECVAM Phase III.

    PubMed

    Heylings, J R; Diot, S; Esdaile, D J; Fasano, W J; Manning, L A; Owen, H M

    2003-04-01

    A prevalidation study sponsored by the European Centre for the Validation of Alternative Methods (ECVAM) on in vitro tests for acute skin irritation is aimed at identifying non-animal tests capable of discriminating irritants (I) from non-irritants (NI), as defined according to European Union and OECD. This paper reports on Phase III for one of the methods, the skin integrity function test (SIFT), assessing the protocol performance of the SIFT, in terms of reproducibility and predictive ability, in three laboratories. The barrier function properties of excised mouse skin were determined using a set of 20 coded chemicals (10 I, 10 NI), using the endpoints of trans-epidermal water loss (TEWL) and electrical resistance (ER). The basis of the SIFT prediction model is if the ratios of the pre- and post-application values for either TEWL or ER are greater than five-fold, then the test chemical is deemed irritant (I). If the ratio of both parameters is less than five-fold then the chemical is deemed non-irritant (NI). Analysis of variance (ANOVA) indicated that the intra-lab reproducibility was acceptable but that the inter-lab reproducibility was not. Overall, the SIFT test under-predicted the irritancy of the test chemicals chosen for Phase III with an overall accuracy of only 55%. The sensitivity value (ability to correctly predict I) was only 30%. The specificity (ability to predict NI) of the test was better at 80%. A retrospective examination of the SIFT results was undertaken using Student's t-test and a significance level of P<0.05 to predict an irritant based on changes in the TEWL ratio values. This improved the predictivity of the SIFT test, giving a specificity of 60%, a sensitivity of 80% and an overall accuracy of 70%. Appropriate modifications to the prediction model have now been made and the SIFT will be re-examined in a new validation exercise to investigate the potential of this non-animal method to predict acute skin irritation potential. PMID:12650665

  8. Application of Advanced Reservoir Characterization, Simulation, and Production Optimization Strategies to Maximize Recovery in Slope and Basin Clastic Reservoirs, West Texas (Delaware Basin), Class III

    SciTech Connect

    Dutton, Shirley P.; Flanders, William A.

    2001-11-04

    The objective of this Class III project was demonstrate that reservoir characterization and enhanced oil recovery (EOR) by CO2 flood can increase production from slope and basin clastic reservoirs in sandstones of the Delaware Mountain Group in the Delaware Basin of West Texas and New Mexico. Phase 1 of the project, reservoir characterization, focused on Geraldine Ford and East Ford fields, which are Delaware Mountain Group fields that produce from the upper Bell Canyon Formation (Ramsey sandstone). The demonstration phase of the project was a CO2 flood conducted in East Ford field, which is operated by Orla Petco, Inc., as the East Ford unit.

  9. Evaluation of biofilm production and characterization of genes encoding type III secretion system among Pseudomonas aeruginosa isolated from burn patients.

    PubMed

    Jabalameli, Fereshteh; Mirsalehian, Akbar; Khoramian, Babak; Aligholi, Marzieh; Khoramrooz, Seyed Sajjad; Asadollahi, Parisa; Taherikalani, Morovat; Emaneini, Mohammad

    2012-12-01

    Pseudomonas aeruginosa is one of the common pathogenic causes of serious infections in burn patients throughout the world. Type III secretion toxins are thought to promote the dissemination of P. aeruginosa from the site of infection, the bacterial evasion of the host immune response and inhibition of DNA synthesis leading to host cell death. A total of 96 isolates of P. aeruginosa were collected from wound infections of burn patients, from April to July 2010. Antimicrobial susceptibility of the isolates were determined by disk agar diffusion method. Polymerase chain reaction (PCR)-based method was used for targeting the genes encoding the type III secretion toxins. The quantitative determination of biofilm-forming capacity was determined by a colorimetric microtiter plate assay. All the isolates were resistant to cefixime and ceftriaxone. More than 90% of the isolates were resistant to amikacin, carbenicillin, cefepime, cefotaxime, cefpodoxime, gatifloxacin, gentamicin, piperacillin/tazobactam, ticarcillin and tobramycin. All the isolates carried the exoT gene, 95% carried exoY, 64.5% carried exoU and 29% carried the exoS gene. Most of the isolates (58%) carried both exoY and exoU genes while 24% showed the concomitant presence of exoS and exoY and 1% carried both exoS and exoU. Coexistence of exoS, exoY and exoU was seen in 4% of the isolates. Biofilm formation was seen in more than 96% of the isolates among which 47% were strong biofilm producers, 26% were moderate and 22.9% were weak biofilm formers. In conclusion, the findings of this study show that the genes, particularly the exoU gene, encoding the type III secretion toxins, are commonly disseminated among the P. aeruginosa strains isolated from burn patients.

  10. Problems of Automatic Test of Insulation in Cable Production

    NASA Astrophysics Data System (ADS)

    Red'ko, V. V.; Leonov, A. P.; Red'ko, L. A.; Bolgova, V. A.

    2016-01-01

    The article presents a qualitative and quantitative assessment of cable products insulation defects that can be reliably detected by means of the electrosparking control during the cable production process. The performance potential of technological control is evaluated: the limit of reliable detection of defective places in insulation taking into account the technical capabilities of modern control devices is marked.

  11. Phase III integrated water recovery testing at MSFC - Partially closed hygiene loop and open potable loop results and lessons learned

    NASA Technical Reports Server (NTRS)

    Bagdigian, R. M.; Traweek, M. S.; Griffith, G. K.; Griffin, M. R.

    1991-01-01

    A series of tests has been conducted at the NASA Marshall Space Flight Center (MSFC) to evaluate the performance of a predevelopment water recovery system. Potable, hygiene, and urine reclamation subsystems were integrated with end-use equipment items and successfully operated in open and partially closed-loop modes, with man-in-the-loop, for a total of 28 days. Several significant subsystem physical anomalies were encountered during testing. Reclaimed potable and hygiene water generally met the current Space Station Freedom (SSF) water quality specifications for inorganic and microbiological constituents, but exceeded the maximum allowable concentrations for Total Organic Carbon (TOC). This paper summarizes the test objectives, system design, test activities/protocols, significant results/anomalies, and major lessons learned.

  12. 46 CFR 160.151-31 - Production inspections and tests of inflatable liferafts.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 6 2010-10-01 2010-10-01 false Production inspections and tests of inflatable liferafts... Liferafts (SOLAS) § 160.151-31 Production inspections and tests of inflatable liferafts. (a) Production.... (b) Each liferaft approved by the Coast Guard must be identified with unique lot and serial...

  13. 76 FR 9028 - Guidance for Industry: Potency Tests for Cellular and Gene Therapy Products; Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-16

    ... Industry: Potency Tests for Cellular and Gene Therapy Products'' dated January 2011. The guidance document provides manufacturers of cellular and gene therapy (CGT) products with recommendations for developing... document entitled ``Guidance for Industry: Potency Tests for Cellular and Gene Therapy Products''...

  14. Estimating dilutions for patch testing skin care products: a practical method.

    PubMed

    Sherertz, E F; Byers, S V

    1997-09-01

    When patch testing, it is helpful to patch test with the patient's own topical products. However, the thickness (viscosity) of the product often prevents easy measurement for dilution. A method of estimating volume: volume dilutions that requires minimal investment in supplies is presented. This method is only applicable to personal products and is not suitable for industrial or household chemicals.

  15. 78 FR 11700 - Notice of Availability: Beta Test of Electronic Product Fulfillment for Addressing and Delivery...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-19

    ...) licensees to test a beta web service that allows the electronic download of these products through the USPS Electronic Product Fulfillment (EPF) Web site. DATES: Interested licensees should submit requests for... licensees to test a beta web service that allows the electronic download of these products through the...

  16. Coal desulfurization by chlorinolysis production and combustion test evaluation of product coals

    NASA Technical Reports Server (NTRS)

    Kalvinskas, J. J.; Daly, D.

    1982-01-01

    Laboratory-scale screening tests were carried out on coal from Harrison County, Ohio to establish chlorination and hydrodesulfurization conditions for the batch reactor production of chlorinolysis and chlorinolysis-hydrodesulfurized coals. In addition, three bituminous coals, were treated on the lab scale by the chlorinolysis process to provide 39 to 62% desulfurization. Two bituminous coals and one subbituminous coal were then produced in 11 to 15 pound lots as chlorinolysis and hydrodesulfurized coals. The chlorinolysis coals had a desulfurization of 29-69%, reductions in voltatiles and hydrogen. Hydrodesulfurization provided a much greater desulfurization (56-86%), reductions in volatiles and hydrogen. The three coals were combustion tested in the Penn State ""plane flame furnace'' to determine ignition and burning characteristics. All three coals burned well to completion as: raw coals, chlorinolysis processed coals, and hydrodesulfurized coals. The hydrodesulfurized coals experienced greater ignition delays and reduced burning rates than the other coals because of the reduced volatile content. It is thought that the increased open pore volume in the desulfurized-devolatilized coals compensates in part for the decreased volatiles effect on ignition and burning.

  17. Environmental testing of block 3 solar cell modules. Part 1: Qualification testing of standard production modules

    NASA Technical Reports Server (NTRS)

    Griffith, J. S.

    1979-01-01

    Qualification tests of solar cell modules are described. These modules continue to show improvement over earlier type modules tested. Cell cracking and delamination are less prevalent, and interconnect problems and electrical degradation from environmental testing are now rare.

  18. The roles of production and preservation during Oceanic Anoxic Event III: A multi-proxy record from the Western Interior Seaway

    NASA Astrophysics Data System (ADS)

    Tessin, A. C.; Hendy, I. L.; Sheldon, N. D.

    2013-12-01

    Cretaceous marine deposits are characterized by periods of enhanced organic carbon burial, known as Oceanic Anoxic Events (OAEs). A major unresolved debate about OAEs is whether changes in preservation or production are responsible for organic carbon burial. To address this question it is important to determine the relative roles of reducing bottom water conditions and surface water primary productivity at the onset of the event. Here we examine the Coniacian-Santonian event (OAE III) using high-resolution major element and trace metal records of the Niobrara Formation recovered in the USGS #1 Portland core from Cañon City Basin, Colorado. Preliminary results of redox sensitive trace metals (Re, Mo, U) and trace metals associated with organic matter (Cd, Ag) indicate that both bottom water suboxia and elevated primary productivity played a role in organic carbon burial during OAE III. The onset of organic carbon accumulation is characterized by two distinct periods of redox-sensitive trace metal enrichments indicating that initial carbon burial is associated with the development of bottom water suboxia. The second enrichment is followed by a shift in trace metal baseline values. Elevated concentrations of Cd and Ag without corresponding major enrichments in Re, Mo and U indicate the increased influence of high primary productivity. We compare trace metals records with bulk organic analyses (%TOC, C:N ratios, and organic carbon isotopes) to further elucidate the relationship between organic carbon accumulation, primary productivity, and bottom water oxygenation. Results from the Portland core are also compared to nearby cores in Colorado and Kansas to evaluate spatial variability throughout the carbon burial event, to examine differences between marginal and open seaway records, and to assess the role of proximity to terrestrial input.

  19. Comparison of NEXRAD Stage III and MPE precipitation products with constraints from high quality and density of raingauge networks in the Upper Guadalupe River Basin, Central Texas

    NASA Astrophysics Data System (ADS)

    Xie, H.; Wang, X.

    2006-05-01

    NEXRAD's Multisensor Precipitation Estimator (MPE) product replaced the Stage III product started in October 2003 at the West Gulf River Forecast Center (WGRFC) where includes most of the Texas and New Mexico. The MPE is an integrated product of rain gauge, NEXRAD, and satellite (GOES) precipitation estimates. The main objective of MPE is to reduce both areal-mean bias error and local bias error. The overall improved quality of MPE over Stage 3 is evident at the WGRFC. However, so far, there is no quantitative evaluation in a relative long period (one year or more) of a large area. In this study, high quality and density of 50 raingauge networks (6 minutes temporal resolution) in the Upper Guadalupe River Basin, Central Texas are used to evaluate both the Stage III (years 2001 and 2002) and MPE (year 2004) products. In this study, we propose two types of comparison (1) directly compare collocated radar cell and gauge of all rainfall events and (2) only compare collocated radar cell and gauge of homogeneous/uniform rainfall events. To find uniform rainfall events, 6-mintutes raingauge rainfall were used to calculate the correlation coefficient (CC) and coefficient of variation (CV) of a hour among one central gauge and its surrounding gauges (>= 4). For a particular rainfall hour, when CV is < 0.5 and CC is > 0.5, or CV is <0.1, the rainfall event of this hour is thus selected as a uniform or homogeneous rainfall event. Our preliminary results of CC from all rainfall events and homogeneous rainfall events for year 2004 (MPE) are 0.79 and 0.96, respectively. This indicates an overall good quality of MPE product in comparison with raingauge rainfall, especially for the homogeneous rainfall events. Work is in progress.

  20. 46 CFR 164.023-13 - Production tests and inspections.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... otherwise specified in the referenced test procedure) on each lot of thread: (1) Breaking strength. One... strength. At least quarterly, one sample in each of the lightest and darkest colors accepted must be tested....023-13 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT, CONSTRUCTION,...

  1. 46 CFR 164.023-13 - Production tests and inspections.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... otherwise specified in the referenced test procedure) on each lot of thread: (1) Breaking strength. One... strength. At least quarterly, one sample in each of the lightest and darkest colors accepted must be tested....023-13 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT, CONSTRUCTION,...

  2. 46 CFR 164.023-13 - Production tests and inspections.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... otherwise specified in the referenced test procedure) on each lot of thread: (1) Breaking strength. One... strength. At least quarterly, one sample in each of the lightest and darkest colors accepted must be tested....023-13 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT, CONSTRUCTION,...

  3. 46 CFR 164.023-13 - Production tests and inspections.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... otherwise specified in the referenced test procedure) on each lot of thread: (1) Breaking strength. One... strength. At least quarterly, one sample in each of the lightest and darkest colors accepted must be tested....023-13 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT, CONSTRUCTION,...

  4. 46 CFR 160.171-25 - Production testing.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT, CONSTRUCTION, AND MATERIALS... from the same lot must be selected at random and subjected to the test. If a defect in the suit is... examined for the defect. (d) If one or more of the 10 suits fails to pass the test or examination,...

  5. 21 CFR 355.70 - Testing procedures for fluoride dentifrice drug products.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 5 2013-04-01 2013-04-01 false Testing procedures for fluoride dentifrice drug... SERVICES (CONTINUED) DRUGS FOR HUMAN USE ANTICARIES DRUG PRODUCTS FOR OVER-THE-COUNTER HUMAN USE Testing Procedures § 355.70 Testing procedures for fluoride dentifrice drug products. (a) A fluoride dentifrice...

  6. 78 FR 29780 - Fees for Testing, Evaluation, and Approval of Mining Products

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-21

    ... Safety and Health Administration Fees for Testing, Evaluation, and Approval of Mining Products AGENCY...) contains new authority for 30 CFR part 5, Fees for testing, evaluation, and approval of mining products; it allows MSHA to collect fees up to $2,499,000 for the testing, evaluation, and approval of certain...

  7. 40 CFR 1051.345 - What production-line testing records must I send to EPA?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... (CONTINUED) AIR POLLUTION CONTROLS CONTROL OF EMISSIONS FROM RECREATIONAL ENGINES AND VEHICLES Testing... Air Act. Our production-line testing conformed completely with the requirements of 40 CFR part 1051. We have not changed production processes or quality-control procedures for test engines (or...

  8. 40 CFR 1051.345 - What production-line testing records must I send to EPA?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... (CONTINUED) AIR POLLUTION CONTROLS CONTROL OF EMISSIONS FROM RECREATIONAL ENGINES AND VEHICLES Testing... Air Act. Our production-line testing conformed completely with the requirements of 40 CFR part 1051. We have not changed production processes or quality-control procedures for test engines (or...

  9. 40 CFR 1051.345 - What production-line testing records must I send to EPA?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... (CONTINUED) AIR POLLUTION CONTROLS CONTROL OF EMISSIONS FROM RECREATIONAL ENGINES AND VEHICLES Testing... Air Act. Our production-line testing conformed completely with the requirements of 40 CFR part 1051. We have not changed production processes or quality-control procedures for test engines (or...

  10. 40 CFR 1051.345 - What production-line testing records must I send to EPA?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... (CONTINUED) AIR POLLUTION CONTROLS CONTROL OF EMISSIONS FROM RECREATIONAL ENGINES AND VEHICLES Testing... Air Act. Our production-line testing conformed completely with the requirements of 40 CFR part 1051. We have not changed production processes or quality-control procedures for test engines (or...

  11. 76 FR 2930 - Market Test of Experimental Product: “Gift Cards”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-18

    ... From the Federal Register Online via the Government Publishing Office POSTAL SERVICE Market Test... Postal Service gives notice of a market test of an experimental product in accordance with statutory...) that it will begin a market test of its ``Gift Cards'' experimental product on or around May 1,...

  12. 77 FR 64566 - Market Test of Experimental Product-Metro Post

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-22

    ... Market Test of Experimental Product--Metro Post AGENCY: Postal Regulatory Commission. ACTION: Notice. SUMMARY: The Commission is noticing a recently-filed Postal Service proposal to conduct a market test involving the product called Metro Post. This document describes the proposed test, addresses...

  13. 75 FR 16874 - Market Test of “Samples Co-Op Box” Experimental Product

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-02

    ... From the Federal Register Online via the Government Publishing Office POSTAL SERVICE Market Test...: The Postal Service gives notice of a market test of an experimental product in accordance with...) that it will begin a market test of its ``Samples Co-Op Box'' experimental product on May 1, 2010....

  14. 77 FR 64366 - Market Test of Experimental Product-Metro Post

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-19

    ... From the Federal Register Online via the Government Publishing Office POSTAL SERVICE Market Test... Service gives notice of a market test of an experimental product in accordance with statutory requirements... 39 U.S.C. 3641(c)(1), it will begin a market test of its Metro Post experimental product on or...

  15. Solvent dependent photosensitized singlet oxygen production from an Ir(III) complex: pointing to problems in studies of singlet-oxygen-mediated cell death.

    PubMed

    Takizawa, Shin-ya; Breitenbach, Thomas; Westberg, Michael; Holmegaard, Lotte; Gollmer, Anita; Jensen, Rasmus L; Murata, Shigeru; Ogilby, Peter R

    2015-10-01

    A cationic cyclometallated Ir(III) complex with 1,10-phenanthroline and 2-phenylpyridine ligands photosensitizes the production of singlet oxygen, O2(a(1)Δ(g)), with yields that depend appreciably on the solvent. In water, the quantum yield of photosensitized O2(a(1)Δ(g)) production is small (ϕ(Δ) = 0.036 ± 0.008), whereas in less polar solvents, the quantum yield is much larger (ϕ(Δ) = 0.54 ± 0.05 in octan-1-ol). A solvent effect on ϕ(Δ) of this magnitude is rarely observed and, in this case, is attributed to charge-transfer-mediated processes of non-radiative excited state deactivation that are more pronounced in polar solvents and that kinetically compete with energy transfer to produce O2(a(1)Δ(g)). A key component of this non-radiative deactivation process, electronic-to-vibrational energy transfer, is also manifested in pronounced H2O/D2O isotope effects that indicate appreciable coupling between the Ir(III) complex and water. This Ir(III) complex is readily incorporated into HeLa cells and, upon irradiation, is cytotoxic as a consequence of the O2(a(1)Δ(g)) thus produced. The data reported herein point to a pervasive problem in mechanistic studies of photosensitized O2(a(1)Δ(g))-mediated cell death: care must be exercised when interpreting the effective cytotoxicity of O2(a(1)Δ(g)) photosensitizers whose photophysical properties depend strongly on the local environment. Specifically, the photophysics of the sensitizer in bulk solutions may not accurately reflect its intracellular behavior, and the control and quantification of the O2(a(1)Δ(g)) "dose" can be difficult in vivo.

  16. 21 CFR 640.82 - Tests on final product.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...) Protein concentration. Final product shall conform to one of the following concentrations: 4.0 ±0.25 percent; 5.0 ±0.30 percent; 20.0 ±1.2 percent; and 25.0 ±1.5 percent solution of protein. (b) Protein composition. At least 96 percent of the total protein in the final product shall be albumin, as determined...

  17. Kinetic and kinematic responses of post mortem human surrogates and the Hybrid III ATD in high-speed frontal sled tests.

    PubMed

    Beeman, Stephanie M; Kemper, Andrew R; Madigan, Michael L; Duma, Stefan M

    2013-06-01

    Despite improvements in vehicle design and safety technologies, frontal automotive collisions continue to result in a substantial number of injuries and fatalities each year. Although a considerable amount of research has been performed on PMHSs and ATDs, matched dynamic whole-body frontal testing with PMHSs and the current ATD aimed at quantifying both kinetic and kinematic data in a single controlled study is lacking in the literature. Therefore, a total of 4 dynamic matched frontal sled tests were performed with three male PMHSs and a Hybrid III 50th percentile male ATD (28.6g, Δv=40 kph). Each subject was restrained using a 4 kN load limiting, driver-side, 3-point seatbelt. Belt force was measured for the lap belt and shoulder belt. Reaction forces were measured at the seat pan, seat back, independent foot plates, and steering column. Linear head acceleration, angular head acceleration, and pelvic acceleration were measured for all subjects. Acceleration of C7, T7, T12, both femurs, and both tibias were also measured for the PMHSs. A Vicon motion analysis system, consisting of 12 MX-T20 2 megapixel cameras, was used to quantify subject 3D motion (±1 mm) at a rate of 1 kHz. Excursions of select anatomical regions were normalized to their respective initial positions and compared by test condition and between subject types. Notable discrepancies were observed in the responses of the PMHSs and the ATD. The reaction forces and belt loading for the ATD, particularly foot plate, seat back, steering column, and lap belt forces, were not in agreement with those of the PMHSs. The forward excursions of the ATD were consistently within those of the PMHSs with the exception of the left upper extremity. This could potentially be due to the known limitations of the Hybrid III ATD shoulder and chest. The results presented herein demonstrate that there are some limitations to the current Hybrid III ATD under the loading conditions evaluated in the current study. Overall

  18. Developing and Testing Simulated Occupational Experiences for Distributive Education Students in Rural Communities: Volume III: Training Plans: Final Report.

    ERIC Educational Resources Information Center

    Virginia Polytechnic Inst. and State Univ., Blacksburg.

    Volume 3 of a three volume final report presents prototype job training plans developed as part of a research project which pilot tested a distributive education program for rural schools utilizing a retail store simulation plan. The plans are for 15 entry-level and 15 career-level jobs in seven categories of distributive business (department…

  19. Underground gasification for steeply dipping coal beds: Phase III. Quarterly progress report, April 1-June 30, 1981. [Rawlins Test 2

    SciTech Connect

    Not Available

    1981-12-01

    Preparations are being made for the August start-up of Rawlins Test 2. Site construction activities began May 4 with the mobilization of the construction subcontractor. The drilling program was completed this quarter with the installation of instrumentation wells. The Experimental Basis Document, PGA Operating Manual, and DAS Operating Manual have also been completed.

  20. The National Council for Geographic Education Competency-Based Geography Test. Secondary Level. Form I. Parts I, II, and III.

    ERIC Educational Resources Information Center

    Kurfman, Dana G.; And Others

    A 3-part test measures the geography knowledge, skills, and understanding of secondary level students. Part 1, map skills and location, contains 20 questions involving the use of three maps: an imaginary sketch map, a contour map, and a political map of the world. Part 2 consists of 20 questions covering physical geography. Students analyze…

  1. Limited In Vivo Production of Type I or Type III Interferon After Infection of Macaques with Vaccine or Wild-Type Strains of Measles Virus

    PubMed Central

    Shivakoti, Rupak; Hauer, Debra; Adams, Robert J.; Lin, Wen-Hsuan W.; Duprex, William Paul; de Swart, Rik L.

    2015-01-01

    The innate immune response to viral infections often includes induction of types I and III interferons (IFNs) and production of antiviral proteins. Measles is a severe virus-induced rash disease, but in vitro studies suggest that in the absence of defective interfering RNAs, neither wild-type (WT) nor vaccine strains of measles virus (MeV) induce IFN. To determine whether IFN is produced in vivo, we studied tissues from macaques infected with vaccine or WT strains of MeV using quantitative reverse transcriptase–polymerase chain reaction to assess levels of IFN and IFN-stimulated gene (ISG) mRNAs and a flow cytometry-based bioassay to assess levels of biologically active IFN. There was little to no induction of type I IFN, type III IFN, Mx, or ISG56 mRNAs in monkeys infected with vaccine or WT MeV and no IFN detection by bioassay. Therefore, the innate responses to infection with vaccine or WT strains of MeV are not dependent on IFN production. PMID:25517681

  2. TESTING THE NO-HAIR THEOREM WITH OBSERVATIONS IN THE ELECTROMAGNETIC SPECTRUM. III. QUASI-PERIODIC VARIABILITY

    SciTech Connect

    Johannsen, Tim; Psaltis, Dimitrios E-mail: dpsaltis@email.arizona.edu

    2011-01-01

    According to the no-hair theorem, astrophysical black holes are uniquely described by their masses and spins. An observational test of the no-hair theorem can be performed by measuring at least three different multipole moments of the spacetime of a black hole and verifying whether their values are consistent with the unique combinations of the Kerr solution. In this paper, we study quasi-periodic variability observed in the emission from black holes across the electromagnetic spectrum as a test of the no-hair theorem. We derive expressions for the Keplerian and epicyclic frequencies in a quasi-Kerr spacetime, in which the quadrupole moment is a free parameter in addition to mass and spin. We show that, for moderate spins, the Keplerian frequency is practically independent of small deviations of the quadrupole moment from the Kerr value, while the epicyclic frequencies exhibit significant variations. We apply this framework to quasi-periodic oscillations (QPOs) in black hole X-ray binaries in two different scenarios. In the case that a pair of QPOs can be identified as the fundamental g- and c-modes in the accretion disk, we show that the no-hair theorem can be tested in conjunction with an independent mass measurement. If pairs of oscillations are identified with non-parametric resonance of dynamical frequencies in the accretion disk, then testing the no-hair theorem also requires an independent measurement of the black hole spin. In addition, we argue that VLBI observations of Sgr A* may test the no-hair theorem through a combination of imaging observations and the detection of quasi-periodic variability.

  3. Influence of phenolic acids on indole acetic acid production and on the type III secretion system gene transcription in food-associated Pseudomonas fluorescens KM05.

    PubMed

    Myszka, Kamila; Schmidt, Marcin T; Olejnik-Schmidt, Agnieszka K; Leja, Katarzyna; Czaczyk, Katarzyna

    2014-12-01

    The purpose of these investigations was to evaluate the reduction capability of phenolic acids (ferulic, chlorogenic, gallic, and p-coumaric acids) on indole acetic acid synthesis by food-associated Pseudomonas fluorescens KM05. Specific genetic primer for the type III secretion system (TTSS) in P. fluorescens KM05 was designed and the influence of phenolic acids on its expression was investigated. In the work the ferulic and chlorogenic acids at the concentration of 0.02 and 0.04 μg/ml affected on bacterial growth pattern and the signal molecules production. The phenolic acids, that were appreciable effective against P. fluorescens KM05 indole acetic acid production, significantly suppressed TTSS gene.

  4. XAFS investigation of the interactions of uranium (VI) with secondary mineralization products from the bioreduction of iron (III) oxides.

    SciTech Connect

    O'Loughlin, E. J.; Kelly, S. D.; Kemner, K. M.

    2010-01-01

    Biogenic Fe{sup II} phases (magnetite, green rust, siderite, vivianite, etc.) provide a reservoir of reducing capacity in many subsurface environments that may contribute to the reduction of contaminants such as U{sup VI}. We have examined the uptake and reduction of U{sup VI} in the presence of biogenic green rust (BioGR), magnetite (BioMAG), and siderite (BioSID) formed during the reduction of Fe{sup III} oxides by Shewanella putrefaciens CN32. Within 48 h, total solution-phase U{sup VI} concentrations decreased from 500{mu}M to 1.5{mu}M, 392{mu}M, and 472{mu}M in the U-BioGR, U-BioMAG, and U-BioSID systems, respectively. Analysis of the samples by U L{sub III} extended X-ray absorption fine structure spectroscopy (EXAFS) indicated that despite a stoichiometric excess of Fe{sup II}, no more than 6% of U{sup VI} was reduced to U{sup IV} in the U-BioSID system, and no more than 22% of U{sup VI} was reduced in the U-BioMAG system. For comparison, in the U-BioGR system, >99% of U{sup VI} was reduced to U{sup IV}. Uptake of U{sup VI} by BioGR and BioMAG was accompanied by formation of nanoparticulate uraninite. The U EXAFS data for the U-BioSID system were consistent with partial U{sup VI}/U{sup IV} substitution for Fe{sup II} in the surface layer of siderite particles and adsorption of U{sup IV}.

  5. Development of an ASTM standard glass durability test, the Product Consistency Test (PCT), for high level radioactive waste glass

    SciTech Connect

    Jantzen, C.M.; Bibler, N.E.; Beam, D.C.; Ramsey, W.G.

    1994-06-01

    The nation`s first, and the world`s largest, facility to immobilize high-level nuclear waste in durable borosilicate glass has started operation at the Savannah River Site (SRS) in Aiken, South Carolina. The product specifications on the glass wasteform produced in the Defense Waste Processing Facility (DWPF) required extensive characterization of the glass product before actual production began and for continued characterization during production. To aid in this characterization, a glass durability (leach) test was needed that was easily reproducible, could be performed remotely on highly radioactive samples, and could yield results rapidly. Several standard leach tests were examined with a variety of test configurations. Using existing tests as a starting point, the DWPF Product Consistency Test (PCT was developed in which crushed glass samples are exposed to 90 {plus_minus} 2{degree}C deionized water for seven days. Based on extensive testing, including a seven-laboratory round robin and confirmatory testing with radioactive samples, the PCT is very reproducible, yields reliable results rapidly, and can be performed in shielded cell facilities with radioactive samples.

  6. TESTING INDOOR AIR PRODUCTS: ONE APPROACH TO DEVELOPING WIDELY ACCEPTED PROTOCOLS

    EPA Science Inventory

    The paper describes an approach to developing widely acce ted products for testing indoor air products. [NOTE: Research Triangle Institute (RTI) is a partner in the U.S. Environmental Protection Agency's (EPA's) Environmental Technology Verification (ETV) Program with responsibil...

  7. CALiPER Summary of Results. Round 13 of Product Testing

    SciTech Connect

    none,

    2011-10-01

    The Department of Energy (DOE) Commercially Available Light-Emitting Diode (LED) Product Evaluation and Reporting (CALiPER) Program has been purchasing and testing general illumination solid-state lighting (SSL) products since 2006.

  8. Limited Production (LP) Precision Runway Monitor (PRM) Operational Test and Evaluation integration and OT and E Operational Test Plan

    NASA Astrophysics Data System (ADS)

    Livings, Jeffrey

    1995-05-01

    This document defines the Test Plan and corresponding Test Verification Requirements Traceability Matrix (TVRTM) that will be used to conduct the Limited Production (LP) Precision Runway Monitor (PRM) Operational Test and Evaluation (OT and E) Integration and OT and E Operational tests. These tests will be conducted at the Minneapolis-St. Paul International Airport following the Contractor Site Acceptance Test. The LP PRM OT and E test effort will concentrate on Operational Effectiveness and Suitability. The Operational Effectiveness Test consists of a review of the contractor performed Development Test and Evaluation (DT and E) and Site Acceptance Tests. This review will evaluate whether each of the Measures of Effectiveness had been satisfactorily tested and whether the results meet the Minimum Acceptable Operational REquirements MAORs). This review will be conducted solely by test engineers and does not require the PRM system. The Operational Suitability Tests will expose the test participants (Air Traffic (AT) Controllers and Airway Facilities (AF) Technicians) to the PRM system in an operational environment while they perform specified operational procedures. These tests will be conducted in two separate phases: AT Suitability and AF Suitability. Each of these phases is focused on the specific test participants.

  9. Long life nickel electrodes for a nickel-hydrogen cell. III - Results of an accelerated test and failure analyses

    NASA Astrophysics Data System (ADS)

    Lim, H. S.; Verzwyvelt, S. A.

    Nineteen different designs of nickel electrodes were tested in Ni/H2 boiler plate cells in an accelerated low earth orbit cycle regime to the end of their life. The failure analyses of these cells showed that the major performance changes due to the cycling was a severe reduction of their high rate discharge capability rather than an absolute capacity reduction. Many physical changes of the nickel electrodes were observed after the cycling test. These changes include dimensional expansion, sinter rupture, loose black powdering of the active material, morphology changes, active material migration, increase of pore volume, change of pore distribution, and increase of surface area. All of these were caused by active material expansion with cycling. Among these changes, the morphology change which involves migration of active material away from the current collecting nickel sinter appears to be that most responsible for the reduction of the rate capability.

  10. Long life nickel electrodes for a nickel-hydrogen cell. III - Results of an accelerated test and failure analyses

    NASA Technical Reports Server (NTRS)

    Lim, H. S.; Verzwyvelt, S. A.

    1984-01-01

    Nineteen different designs of nickel electrodes were tested in Ni/H2 boiler plate cells in an accelerated low earth orbit cycle regime to the end of their life. The failure analyses of these cells showed that the major performance changes due to the cycling was a severe reduction of their high rate discharge capability rather than an absolute capacity reduction. Many physical changes of the nickel electrodes were observed after the cycling test. These changes include dimensional expansion, sinter rupture, loose black powdering of the active material, morphology changes, active material migration, increase of pore volume, change of pore distribution, and increase of surface area. All of these were caused by active material expansion with cycling. Among these changes, the morphology change which involves migration of active material away from the current collecting nickel sinter appears to be that most responsible for the reduction of the rate capability.

  11. The SAGE III's mission aboard the International Space Station

    NASA Astrophysics Data System (ADS)

    Pitts, Michael; Thomason, Larry; Zawodny, Joseph; Flittner, David; Hill, Charles; Roell, Marilee; Vernier, Jean-Paul

    2014-05-01

    The Stratospheric Aerosol and Gas Experiment (SAGE III) is being prepared for deployment on the International Space Station (ISS) in 2015. Constructed in the early 2000s, the instrument is undergoing extensive testing and refurbishment prior to delivery to ISS. In addition, ESA is refurbishing their Hexapod which is a high-accuracy pointing system developed to support ISS external payloads, particularly SAGE III. The SAGE III instrument refurbishment also includes the replacement of the neutral density filter that has been associated with some instrument performance degradation during the SAGE III mission aboard METEOR/3M mission (2002-2005). We are also exploring options for expanding the science targets to include additional gas species including IO, BrO, and other solar, lunar, and limb-scatter species. In this presentation, we will discuss SAGE III-ISS refurbishment including results from Sun-look testing. We also will discuss potential revisions to the science measurements and the expected measurement accuracies determined in part through examination of the SAGE III-METEOR/3M measurement data quality. In addition, we will discuss potential mission science goals enabled by the mid-inclination ISS orbit. No dedicated field campaign for SAGE III validation is anticipated. Instead, validation will primarily rely on a collaborative effort with international groups making in situ and ground-based measurements of aerosol, ozone, and other SAGE III data products. A limited balloon-based effort with a yet-to-be-determined validation partner is also in the planning stages.

  12. Model testing using Chernobyl data: III. Atmospheric resuspension of radionuclides in Ukrainian regions impacted by Chernobyl fallout

    SciTech Connect

    Garger, E.K.; Hoffman, F.O.; Miller, C.W.

    1996-01-01

    The {open_quotes}Resuspension{close_quotes} scenario is designed to test models for atmospheric resuspension of radionuclides from contaminated soils. Resuspension can be a secondary source of contamination after a release has stopped, as well as a source of contamination for people and areas not exposed to the original release. The test scenario describes three exposure situations: (1) locations within the highly contaminated 30-km zone at Chernobyl, where exposures to resuspended material are probably dominated by local processes; (2) an urban area (Kiev) outside the 30-km zone, where local processes include extensive vehicular traffic; and (3) a location 40 to 60 km west of the Chernobyl reactor, where upwind sources of contamination are important. Input data include characteristics of the {sup 137}Cs ground contamination around specific sites, climatological data for the sites, characteristics of the terrain and topography, and locations of the sampling sites. Predictions are requested for average air concentrations of {sup 137}Cs at specified locations due to resuspension of Chernobyl fallout and for specified resuspension factors and rates. Test data (field measurements) are available for all endpoints. 9 refs., 4 figs., 11 tabs.

  13. Expression of receptors of advanced glycation end product (RAGE) and types I, III and IV collagen in the vastus lateralis muscle of men in early stages of knee osteoarthritis.

    PubMed

    Serrão, Paula Regina M S; Vasilceac, Fernando A; Gramani-Say, Karina; Lessi, Giovanna C; Reiff, Rodrigo B M; Mattiello-Sverzut, Ana Cláudia; Mattiello, Stela M

    2014-01-01

    Alterations in the contractile and non-contractile proteins of the skeletal muscle may reduce muscle function in knee osteoarthritis (OA), and the formation and accumulation of advanced glycation end products, particularly in collagen, can influence the quality of these muscle proteins. The objective of this study was to evaluate the reactivity of types I, III and IV collagen and the expression and localization of receptor for advanced glycation end products (RAGE) in the vastus lateralis (VL) muscle in early stages of knee OA. The hypothesis was that these patients present a higher expression of RAGE and increased immunoreactivity in the collagen. Thirty-five men were divided into two groups: the control group (CG; n = 17) and the osteoarthritis group (OAG; n = 18). All participants were submitted to a biopsy of the VL. The muscle samples were analyzed by immunohistochemistry for collagen and for RAGE and laminin. The expression of RAGE was counted (intracellular, extracellular and total). Student's t-test for independent samples and Mann-Whitney U test were used for the RAGE's intergroup analysis (α ≤ 0.05). A semiquantitative analysis was performed to assess the collagen reactivity. No significant differences were observed in the intracellular, extracellular or total localization of RAGE (p > 0.05). Higher immunoreactivity was observed in the OAG for all types of collagen, with more reactivity for collagen III and IV. We concluded that in the initial stages of knee OA, no differences were observed for RAGE levels between the groups. However, the OAG's higher collagen expression may represent adaptations for reducing muscle stiffness and avoiding injury.

  14. Biological effects of high-LET particles on corn-seed embryos in the Apollo-Soyuz Test Project--Biostack III experiment.

    PubMed

    Peterson, D D; Benton, E V; Tran, M; Yang, T; Freeling, M; Craise, L; Tobias, C A

    1977-01-01

    High-LET particle hits in embryos of Zea mays corn seeds, flown as part of Biostack III in the Apollo-Soyuz Test Project, were determined via plastic nuclear track detectors. Based on etched particle-track measurements, 41 embryos were hit in seed layer 1 which contained 80 seeds, and 49 hits occurred in layer 2 which contained 79 seeds. The mean LET value and range of atomic numbers of recorded hits is, respectively, 210 +/- 57 keV micrometers -1 and 9 < or approximately Z < or approximately 26. Detailed analysis of one particular seed showing marked growth anomalies revealed two hits in the central region of the embryo. These two hits had LET values in the region of 100-150 keV micrometers-1, and Z > or approximately 20.

  15. A Prospective Randomised Phase III Clinical Trial Testing the Role of Prophylactic Cranial Radiotherapy in Patients Treated with Trastuzumab for Metastatic Breast Cancer - Anglo Celtic VII.

    PubMed

    Canney, P; Murray, E; Dixon-Hughes, J; Lewsley, L-A; Paul, J

    2015-08-01

    A high incidence of central nervous system (CNS) metastases has been reported in patients with HER2-positive tumours receiving trastuzumab therapy for metastatic breast cancer. This study tested whether prophylactic cranial irradiation (PCI) could reduce the incidence of CNS metastases in this setting. This was a prospective, randomised phase III trial. Patients were randomised 1:1 to no PCI or PCI delivered at around 6 weeks after study entry. Cognitive function was assessed prospectively. In total, 51 patients were randomised over a 3 year period; 25 received PCI and 26 did not. The cumulative incidence of CNS metastases at 2 years was 32.4% (standard error = 9.8%) on the no PCI arm and 21.0% (standard error = 8.6%) on the PCI arm; the associated hazard ratio was 0.57 (95% confidence interval 0.18-1.74; P = 0.32). There was no evidence of cognitive dysfunction in PCI patients.

  16. Effect of lanthanum(III) on the production of ethylene and reactive oxygen species in soybean seedlings exposed to the enhanced ultraviolet-B radiation.

    PubMed

    Yang, Qing; Li, Yueli; Wang, Lihong; Zhou, Qing; Huang, Xiaohua

    2014-06-01

    The enhanced ultraviolet-B (UV-B) radiation caused by ozone depletion may exert deleterious effects on plants. Therefore, studies on the effect of UV-B radiation on plants, as well as studies on the methods for alleviating the deleterious effects by chemical control, are of great significance. In this study, after soybean (Glycine max) seedlings were exposed to UV-B radiation (10.2 and 13.8kJ m(-2)day(-1)) for 5 days and the followed 6 days of restoration, respectively, the effects of 20mg L(-1) lanthanum (III) [La(III)] on leaf phenotype, photosynthetic rate, and production of ethylene and reactive oxygen species (ROS) were investigated. The results indicated that the exposure to 10.2 and 13.8kJ m(-2)day(-1) UV-B radiation could cause injury to the leaf phenotype, and lead to the decrease in the content of chlorophyll and the net photosynthetic rate, and the increase in the contents of ROS, ethylene and 1-aminocyclopropanecarboxylic acid, and 1-aminocyclopropanecarboxylic acid synthase activity in soybean seedlings. Following the withdrawal of the enhanced UV-B radiation, the above mentioned parameters gradually recovered, and the recovery of soybean seedlings exposed to 10.2kJ m(-2)day(-1) UV-B radiation was faster than those in soybean seedlings exposed to 13.8kJ m(-2)day(-1) UV-B radiation. The leaf injury and the changes in the above indices that were induced by the enhanced UV-B radiation, especially at 10.2kJ m(-2)day(-1), were alleviated after the pretreatment of soybean seedlings with 20mg L(-1) La(III). The results of the correlation analysis demonstrated that the injury to the leaf phenotype and the decrease in the photosynthetic rate of soybean seedlings were correlated with the increase in the ROS content that was induced by ethylene in soybean seedlings. The pretreatment with 20mg L(-1) La(III) alleviated the injury caused by the enhanced UV-B radiation through the regulation of the ROS production.

  17. Effect of lanthanum(III) on the production of ethylene and reactive oxygen species in soybean seedlings exposed to the enhanced ultraviolet-B radiation.

    PubMed

    Yang, Qing; Li, Yueli; Wang, Lihong; Zhou, Qing; Huang, Xiaohua

    2014-06-01

    The enhanced ultraviolet-B (UV-B) radiation caused by ozone depletion may exert deleterious effects on plants. Therefore, studies on the effect of UV-B radiation on plants, as well as studies on the methods for alleviating the deleterious effects by chemical control, are of great significance. In this study, after soybean (Glycine max) seedlings were exposed to UV-B radiation (10.2 and 13.8kJ m(-2)day(-1)) for 5 days and the followed 6 days of restoration, respectively, the effects of 20mg L(-1) lanthanum (III) [La(III)] on leaf phenotype, photosynthetic rate, and production of ethylene and reactive oxygen species (ROS) were investigated. The results indicated that the exposure to 10.2 and 13.8kJ m(-2)day(-1) UV-B radiation could cause injury to the leaf phenotype, and lead to the decrease in the content of chlorophyll and the net photosynthetic rate, and the increase in the contents of ROS, ethylene and 1-aminocyclopropanecarboxylic acid, and 1-aminocyclopropanecarboxylic acid synthase activity in soybean seedlings. Following the withdrawal of the enhanced UV-B radiation, the above mentioned parameters gradually recovered, and the recovery of soybean seedlings exposed to 10.2kJ m(-2)day(-1) UV-B radiation was faster than those in soybean seedlings exposed to 13.8kJ m(-2)day(-1) UV-B radiation. The leaf injury and the changes in the above indices that were induced by the enhanced UV-B radiation, especially at 10.2kJ m(-2)day(-1), were alleviated after the pretreatment of soybean seedlings with 20mg L(-1) La(III). The results of the correlation analysis demonstrated that the injury to the leaf phenotype and the decrease in the photosynthetic rate of soybean seedlings were correlated with the increase in the ROS content that was induced by ethylene in soybean seedlings. The pretreatment with 20mg L(-1) La(III) alleviated the injury caused by the enhanced UV-B radiation through the regulation of the ROS production. PMID:24675444

  18. 40 CFR 1048.305 - How must I prepare and test my production-line engines?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... of hours you operated your emission-data engine for certifying the engine family (see 40 CFR part... family. (a) Test procedures. Test your production-line engines using either the steady-state or...

  19. Qualitative tests for added coloring matter in meat products.

    PubMed

    McNeal, J E

    1976-05-01

    The rapid qualitative detection of coal tar dyes, chemicals added to color meat products, and some natural coloring materials was investigated through extraction and subsequent identification by spectrophotometric, paper chromatographic, and specific reaction techniques. These techniques will detect the presence of coal tar dyes, imidazole, histamine, histidine, cochineal, beet powder, annatto, alkanet, carotene, paprika, saffron, turmeric, and materials causing discoloration in meats.

  20. The infrared light curve of Periodic Comet Halley 1986 III and its relationship to the visual light curve, C2, and water production rates

    NASA Technical Reports Server (NTRS)

    Morris, Charles S.; Hanner, Martha S.

    1993-01-01

    The near-IR light curve of Periodic Comet Halley 1986 III is analyzed and compared with C2 production, water production, and the visual light curve. This is the most complete IR light curve compiled to date for any comet. The scattering phase function at small sun-comet-earth angles is shown to affect the slope of near-IR light curve significantly. P/Halley's dust production, as inferred from the IR light curve showed an increased production rate near perihelion which appears to be correlated with the onset of significant jet activity. The near-IR light curve, visual light curve, C2, and water production rates displayed different heliocentric variations, suggesting that one parameter cannot be accurately estimated from another. This is particularly true of the early preperihelion visual light curve. A peak of 0.3-0.5 magnitude in the visual magnitude, representing the integrated brightness of the comet's visible coma, lagged the other parameters by about a day. The near-IR color, J-H, was less red during periods of strong dust activity.

  1. Facility for generating crew waste water product for ECLSS testing

    NASA Technical Reports Server (NTRS)

    Buitekant, Alan; Roberts, Barry C.

    1990-01-01

    An End-use Equipment Facility (EEF) has been constructed which is used to simulate water interfaces between the Space Station Freedom Environmental Control and Life Support Systems (ECLSS) and man systems. The EEF is used to generate waste water to be treated by ECLSS water recovery systems. The EEF will also be used to close the water recovery loop by allowing test subjects to use recovered hygiene and potable water during several phases of testing. This paper describes the design and basic operation of the EEF.

  2. The Challenge of Validation: Assessing the Performance of a Test of Productive Vocabulary

    ERIC Educational Resources Information Center

    Fitzpatrick, Tess; Clenton, Jon

    2010-01-01

    This paper assesses the performance of a vocabulary test designed to measure second language productive vocabulary knowledge.The test, Lex30, uses a word association task to elicit vocabulary, and uses word frequency data to measure the vocabulary produced. Here we report firstly on the reliability of the test as measured by a test-retest study, a…

  3. 46 CFR 160.076-31 - Production tests and examinations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... requirements in § 160.076-21 (b) and (c) for permeability, grab strength, and tear strength. Lots not meeting... retested. (2) Seam strength. The seams in each inflation chamber of each sample must be tested in... loss and the same percentage sensitivity and accuracy as the standard allowable loss measured with...

  4. 46 CFR 160.076-31 - Production tests and examinations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... specifications. (ii) The torque of each screw type mechanical fastener must be within its tolerance as prescribed... apparent defects. (8) Waterproof Marking Test. Each sample must be completely submerged in fresh water for... general arrangement and attachment of all components, such as body straps, closures, inflation...

  5. 46 CFR 160.022-4 - Approval and production tests.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... cumulative sample size is met. If any signal in the sample explodes when fired or ignited in a way that could.... Ignite specimen and let it burn about 15 seconds in air. Submerge the burning signal in water in a.... Insert a No. 6 commercial blasting cap. Ignite the cap. The test specimen shall not explode or ignite....

  6. 46 CFR 160.024-4 - Approval and production tests.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... reworking performed on the rejected lot, and the results of the second test. (1) Lot size. For the purposes... descent shall not exceed 1.8 m (6 ft.) per second. (v) Burning time. The burning time of the pyrotechnic... until it ceases. The burning time shall be not less than 30 seconds. EC03MR91.006 Table...

  7. 46 CFR 160.028-4 - Approval and production tests.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... the chamber and bore dimensions is not required. (2) Inspections and tests by an independent... the chamber and bore dimensions of the pistol. (2) Fire a dummy cartridge simulating a normal signal....009 (4) Recheck the chamber and bore dimensions. (5) The pistol must fire the signal properly,...

  8. 46 CFR 160.077-23 - Production tests and inspections.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... sufficient to allow a water depth of at least 5 cm (2 inches) from the water surface to the top of the basket... fixed anchor, or (C) a tensile test machine that is capable of holding a given tension. The assembly... submerged in fresh water for at least 30 min. and then removed and immediately placed on a hard surface....

  9. 46 CFR 160.077-23 - Production tests and inspections.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... sufficient to allow a water depth of at least 5 cm (2 inches) from the water surface to the top of the basket... fixed anchor, or (C) a tensile test machine that is capable of holding a given tension. The assembly... submerged in fresh water for at least 30 min. and then removed and immediately placed on a hard surface....

  10. 46 CFR 160.077-23 - Production tests and inspections.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... sufficient to allow a water depth of at least 5 cm (2 inches) from the water surface to the top of the basket... fixed anchor, or (C) a tensile test machine that is capable of holding a given tension. The assembly... submerged in fresh water for at least 30 min. and then removed and immediately placed on a hard surface....

  11. 46 CFR 160.077-23 - Production tests and inspections.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... sufficient to allow a water depth of at least 5 cm (2 inches) from the water surface to the top of the basket... fixed anchor, or (C) a tensile test machine that is capable of holding a given tension. The assembly... submerged in fresh water for at least 30 min. and then removed and immediately placed on a hard surface....

  12. 46 CFR 164.023-13 - Production tests and inspections.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... grain-yarn scale, accurate to within 0.25 percent of the measured value. (b) Lot size. Lot size must not... laboratory inspector at the manufacturer's plant, at the laboratory's discretion. (g) Accept/reject criteria... the acceptance testing values but not less than the performance minimums. (2) Length/weight...

  13. How Do Executive Functions Fit with the Cattell-Horn-Carroll Model? Some Evidence from a Joint Factor Analysis of the Delis-Kaplan Executive Function System and the Woodcock-Johnson III Tests of Cognitive Abilities

    ERIC Educational Resources Information Center

    Floyd, Randy G.; Bergeron, Renee; Hamilton, Gloria; Parra, Gilbert R.

    2010-01-01

    This study investigated the relations among executive functions and cognitive abilities through a joint exploratory factor analysis and joint confirmatory factor analysis of 25 test scores from the Delis-Kaplan Executive Function System and the Woodcock-Johnson III Tests of Cognitive Abilities. Participants were 100 children and adolescents…

  14. Status of Santa Clara MCFC product development test

    SciTech Connect

    Leo, A.J.; O`Shea, T.P.

    1995-08-01

    The objective of the 2MW Santa Clara Demonstration Project is the demonstration of the carbonate fuel cell technology at full scale. Additional objectives of the project include the demonstration of specific advantages of the direct carbonate fuel cell power plant, such as high efficiency, low emissions, reactive power capability, and high reliability and availability. The project will also provide design input for precommercial early production power plants.

  15. 46 CFR 160.176-15 - Production tests and inspections.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...) Seam Strength 1 1 2 2 3 4 Over-pressure 2,3 1 2 3 4 6 8 Air Retention EVERY DEVICE IN THE LOT Buoyancy & Inflation Media Retention 1 2 3 4 6 8 Tensile Strength 4 1 1 1 1 1 1 Detailed Product Examination 2 2 3 4 6... Buoyancy & Inflation Media Retention 1 2 3 4 6 8 Tensile Strength 2 1 1 1 1 1 1 Waterproof marking SEE...

  16. Induction of dendritic cell production of type I and type III interferons by wild-type and vaccine strains of measles virus: role of defective interfering RNAs.

    PubMed

    Shivakoti, Rupak; Siwek, Martina; Hauer, Debra; Schultz, Kimberly L W; Griffin, Diane E

    2013-07-01

    The innate immune response to viral infection frequently includes induction of type I interferons (IFN), but many viruses have evolved ways to block this response and increase virulence. In vitro studies of IFN production after infection of susceptible cells with measles virus (MeV) have often reported greater IFN synthesis after infection with vaccine than with wild-type strains of MeV. However, the possible presence in laboratory virus stocks of 5' copy-back defective interfering (DI) RNAs that induce IFN independent of the standard virus has frequently confounded interpretation of data from these studies. To further investigate MeV strain-dependent differences in IFN induction and the role of DI RNAs, monocyte-derived dendritic cells (moDCs) were infected with the wild-type Bilthoven strain and the vaccine Edmonston-Zagreb strain with and without DI RNAs. Production of type I IFN, type III IFN, and the interferon-stimulated genes (ISGs) Mx and ISG56 by infected cells was assessed with a flow cytometry-based IFN bioassay, quantitative reverse transcriptase PCR (RT-PCR), and immunoassays. Bilthoven infected moDCs less efficiently than Edmonston-Zagreb. Presence of DI RNAs in vaccine stocks resulted in greater maturation of moDCs, inhibition of virus replication, and induction of higher levels of IFN and ISGs. Production of type I IFN, type III IFN, and ISG mRNA and protein was determined by both the level of infection and the presence of DI RNAs. At the same levels of infection and in the absence of DI RNA, IFN induction was similar between wild-type and vaccine strains of MeV. PMID:23678166

  17. Helicon Discharge with Selectable Nitrogen Reactive Species Production as a Plasma Source for III-group Nitrides Growth by MBE

    NASA Astrophysics Data System (ADS)

    Biloiu, Costel; Doss, Forest; Scime, Earl

    2004-11-01

    Plasma assisted molecular beam epitaxy (PAMBE) of III-N materials is a potential alternative to MOCVD for fabrication of high quality wide band gap semiconductor devices. In the helicon plasma source, it may be possible to control the population of specific reactive nitrogen species by modification of the electron energy distribution function through the resonant wave-particle interaction arising from electrons traveling at same velocity as the helicon wave phase velocity. We report preliminary results on control of reactive nitrogen species performed in a steady state, high density, helicon plasma source CHEWIE (Compact HElicon Waves and Instabilities Experiment). The helicon vacuum chamber is a 12 cm long, Pyrex tube, 6 cm in diameter, connected to a stainless steel diffusion chamber. RF power of up to 1.0 kW over a frequency range of 3-28 MHz is used to create the steady state plasma. A 7 cm long, half wave, m = +1, helical antenna couples the rf energy into the plasma. A single solenoidal magnetic field coil surrounds the source and is capable of generating axial magnetic fields up to 600 G. Optical emission spectroscopy investigations show that under certain conditions, the decay from the long lived A^3Σ_u^+ state dominates the emission spectrum of the plasma.

  18. Ten Year Operating Test Results and Post-Test Analysis of a 1/10 Segment Stirling Sodium Heat Pipe, Phase III

    NASA Technical Reports Server (NTRS)

    Rosenfeld, John, H; Minnerly, Kenneth, G; Dyson, Christopher, M.

    2012-01-01

    High-temperature heat pipes are being evaluated for use in energy conversion applications such as fuel cells, gas turbine re-combustors, Stirling cycle heat sources; and with the resurgence of space nuclear power both as reactor heat removal elements and as radiator elements. Long operating life and reliable performance are critical requirements for these applications. Accordingly, long-term materials compatibility is being evaluated through the use of high-temperature life test heat pipes. Thermacore, Inc., has carried out a sodium heat pipe 10-year life test to establish long-term operating reliability. Sodium heat pipes have demonstrated favorable materials compatibility and heat transport characteristics at high operating temperatures in air over long time periods. A representative one-tenth segment Stirling Space Power Converter heat pipe with an Inconel 718 envelope and a stainless steel screen wick has operated for over 87,000 hr (10 yr) at nearly 700 C. These life test results have demonstrated the potential for high-temperature heat pipes to serve as reliable energy conversion system components for power applications that require long operating lifetime with high reliability. Detailed design specifications, operating history, and post-test analysis of the heat pipe and sodium working fluid are described.

  19. Architecture-Based Unit Testing of the Flight Software Product Line

    NASA Technical Reports Server (NTRS)

    Ganesan, Dharmalingam; Lindvall, Mikael; McComas, David; Bartholomew, Maureen; Slegel, Steve; Medina, Barbara

    2010-01-01

    This paper presents an analysis of the unit testing approach developed and used by the Core Flight Software (CFS) product line team at the NASA GSFC. The goal of the analysis is to understand, review, and reconunend strategies for improving the existing unit testing infrastructure as well as to capture lessons learned and best practices that can be used by other product line teams for their unit testing. The CFS unit testing framework is designed and implemented as a set of variation points, and thus testing support is built into the product line architecture. The analysis found that the CFS unit testing approach has many practical and good solutions that are worth considering when deciding how to design the testing architecture for a product line, which are documented in this paper along with some suggested innprovennents.

  20. Application for Permit to Operate a Class III Solid Waste Disposal Site at the Nevada Test Site - U10c Disposal Site

    SciTech Connect

    NSTec Environmental Programs

    2010-08-05

    The NTS is located approximately 105 km (65 mi) northwest of Las Vegas, Nevada. NNSA/NSO is the federal lands management authority for the NTS and NSTec is the Management & Operations contractor. Access on and off the NTS is tightly controlled, restricted, and guarded on a 24-hour basis. The NTS is posted with signs along its entire perimeter. NSTec is the operator of all solid waste disposal sites on the NTS. The U10C Disposal Site is located in the northwest corner of Area 9 at the NTS (Figure 1) and is located in a subsidence crater created by two underground nuclear events, one in October 1962 and another in April 1964. The disposal site opened in 1971 for the disposal of rubbish, refuse, pathological waste, asbestos-containing material, and industrial solid waste. A Notice of Intent form to operate the disposal site as a Class II site was submitted to the state of Nevada on January 26, 1994, and was acknowledged in a letter to the DOE on February 8, 1994. It operated as a state of Nevada Class II Solid Waste Disposal Site (SWDS) until it closed on October 5, 1995, for retrofit as a Class III SWDS. The retrofit consisted of the installation of a minimum four-foot compacted soil layer to segregate the different waste types and function as a liner to inhibit leachate and water flow into the lower waste zone. Five neutron monitoring tubes were installed in this layer to monitor possible leachate production and water activity. Upon acceptance of the installed barrier and approval of an Operating Plan by NDEP/BFF, the site reopened in January 1996 as a Class III SWDS for the disposal of industrial solid waste and other inert waste.

  1. Gene and gene-product variation in the apolipoprotein A-I/C-III/A-IV cluster in the Dogrib Indians of the Northwest Territories.

    PubMed Central

    Cole, S A; Szathmary, E J; Ferrell, R E

    1989-01-01

    The Dogrib, an Amerindian tribe residing in the Northwest Territories of Canada, were typed for DNA and protein polymorphism at the apolipoprotein A-I/C-III/A-IV gene cluster. Variation was seen at three previously described RFLPs detected with the enzymes SstI, PstI, and XmnI, though frequencies of these polymorphisms differ significantly from those reported in other populations. They exhibit no variation at two previously reported PvuII sites. No variation was seen in the APO A-I or APO A-IV gene products, with the Dogrib showing the most common isoelectric-focusing/immunoblot patterns of other world populations. Haplotype frequencies computed from inferred haplotypes and by maximum likelihood estimation did not differ significantly. The extent of nonrandom association of these sites is highly significant (P less than .00001), though pairwise analysis shows significance between the SstI and XmnI sites only. Levels of fasting triglyceride and fasting total cholesterol were determined for each individual. Analysis of covariance shows that fasting triglyceride levels in women vary significantly with the XmnI genotype. These results suggest that genetic variation at the APO A-I/C-III/A-IV gene cluster may be a useful tool for the study of quantitative lipoprotein variation in the Dogrib. PMID:2499188

  2. A Geobacter sulfurreducens Strain Expressing Pseudomonas aeruginosa Type IV Pili Localizes OmcS on Pili but Is Deficient in Fe(III) Oxide Reduction and Current Production

    PubMed Central

    Liu, Xing; Tremblay, Pier-Luc; Malvankar, Nikhil S.; Nevin, Kelly P.; Vargas, Madeline

    2014-01-01

    The conductive pili of Geobacter species play an important role in electron transfer to Fe(III) oxides, in long-range electron transport through current-producing biofilms, and in direct interspecies electron transfer. Although multiple lines of evidence have indicated that the pili of Geobacter sulfurreducens have a metal-like conductivity, independent of the presence of c-type cytochromes, this claim is still controversial. In order to further investigate this phenomenon, a strain of G. sulfurreducens, designated strain PA, was constructed in which the gene for the native PilA, the structural pilin protein, was replaced with the PilA gene of Pseudomonas aeruginosa PAO1. Strain PA expressed and properly assembled P. aeruginosa PilA subunits into pili and exhibited a profile of outer surface c-type cytochromes similar to that of a control strain expressing the G. sulfurreducens PilA. Surprisingly, the strain PA pili were decorated with the c-type cytochrome OmcS in a manner similar to the control strain. However, the strain PA pili were 14-fold less conductive than the pili of the control strain, and strain PA was severely impaired in Fe(III) oxide reduction and current production. These results demonstrate that the presence of OmcS on pili is not sufficient to confer conductivity to pili and suggest that there are unique structural features of the G. sulfurreducens PilA that are necessary for conductivity. PMID:24296506

  3. Hanford Immobilized Low-Activity Waste Product Acceptance Test Plan

    SciTech Connect

    Peeler, D.

    1999-06-22

    'The Hanford Site has been used to produce nuclear materials for the U.S. Department of Energy (DOE) and its predecessors. A large inventory of radioactive and mixed waste, largely generated during Pu production, exists in 177 underground single- and double-shell tanks. These wastes are to be retrieved and separated into low-activity waste (LAW) and high-level waste (HLW) fractions. The DOE is proceeding with an approach to privatize the treatment and immobilization of Handord''s LAW and HLW.'

  4. Evaluation of precipitates used in strainer head loss testing : Part III. Long-term aluminum hydroxide precipitation tests in borated water.

    SciTech Connect

    Bahn, C. B.; Kasza, K. E.; Shack, W. J.; Natesan, K.; Klein, P.

    2011-05-01

    Long-term aluminum (Al) hydroxide precipitation tests were conducted in slightly alkaline solutions containing 2500 ppm boron. The solution temperature was cycled to obtain a temperature history more representative of emergency core cooling system temperatures after a loss-of-coolant accident. The observed Al precipitation boundary was close to predicted results for amorphous precipitates, which are higher than the solubility expected for crystalline forms. Bench-scale and loop head loss test results under various conditions were successfully combined into single map in a temperature - 'pH + p[Al]{sub T}' domain, which yielded two bounding lines for Al hydroxide solubility in borated alkaline water that depend on whether or not loop head loss tests with Al alloy coupons are included. Precipitates were observed to form either as fine, cloudy suspensions, which showed very little tendency to settle, or as flocculated precipitates. The flocculation tendency of the precipitates can be qualitatively explained by a colloid stability theory or a phase diagram for protein solutions.

  5. Evaluation of long-term gas hydrate production testing locations on the Alaska north slope

    USGS Publications Warehouse

    Collett, T.S.; Boswell, R.; Lee, M.W.; Anderson, B.J.; Rose, K.; Lewis, K.A.

    2011-01-01

    The results of short duration formation tests in northern Alaska and Canada have further documented the energy resource potential of gas hydrates and justified the need for long-term gas hydrate production testing. Additional data acquisition and long-term production testing could improve the understanding of the response of naturally-occurring gas hydrate to depressurization-induced or thermal-, chemical-, and/or mechanical-stimulated dissociation of gas hydrate into producible gas. The Eileen gas hydrate accumulation located in the Greater Prudhoe Bay area in northern Alaska has become a focal point for gas hydrate geologic and production studies. BP Exploration (Alaska) Incorporated and ConocoPhillips have each established research partnerships with U.S. Department of Energy to assess the production potential of gas hydrates in northern Alaska. A critical goal of these efforts is to identify the most suitable site for production testing. A total of seven potential locations in the Prudhoe Bay, Kuparuk, and Milne Point production units were identified and assessed relative to their suitability as a long-term gas hydrate production test site. The test site assessment criteria included the analysis of the geologic risk associated with encountering reservoirs for gas hydrate testing. The site selection process also dealt with the assessment of the operational/logistical risk associated with each of the potential test sites. From this review, a site in the Prudhoe Bay production unit was determined to be the best location for extended gas hydrate production testing. The work presented in this report identifies the key features of the potential test site in the Greater Prudhoe Bay area, and provides new information on the nature of gas hydrate occurrence and potential impact of production testing on existing infrastructure at the most favorable sites. These data were obtained from well log analysis, geological correlation and mapping, and numerical simulation

  6. Evaluation of long-term gas hydrate production testing locations on the Alaska North Slope

    USGS Publications Warehouse

    Collett, Timothy; Boswell, Ray; Lee, Myung W.; Anderson, Brian J.; Rose, Kelly K.; Lewis, Kristen A.

    2011-01-01

    The results of short duration formation tests in northern Alaska and Canada have further documented the energy resource potential of gas hydrates and justified the need for long-term gas hydrate production testing. Additional data acquisition and long-term production testing could improve the understanding of the response of naturally-occurring gas hydrate to depressurization-induced or thermal-, chemical-, and/or mechanical-stimulated dissociation of gas hydrate into producible gas. The Eileen gas hydrate accumulation located in the Greater Prudhoe Bay area in northern Alaska has become a focal point for gas hydrate geologic and production studies. BP Exploration (Alaska) Incorporated and ConocoPhillips have each established research partnerships with U.S. Department of Energy to assess the production potential of gas hydrates in northern Alaska. A critical goal of these efforts is to identify the most suitable site for production testing. A total of seven potential locations in the Prudhoe Bay, Kuparuk, and Milne Point production units were identified and assessed relative to their suitability as a long-term gas hydrate production test site. The test site assessment criteria included the analysis of the geologic risk associated with encountering reservoirs for gas hydrate testing. The site selection process also dealt with the assessment of the operational/logistical risk associated with each of the potential test sites. From this review, a site in the Prudhoe Bay production unit was determined to be the best location for extended gas hydrate production testing. The work presented in this report identifies the key features of the potential test site in the Greater Prudhoe Bay area, and provides new information on the nature of gas hydrate occurrence and potential impact of production testing on existing infrastructure at the most favorable sites. These data were obtained from well log analysis, geological correlation and mapping, and numerical simulation.

  7. Evaluation of long-term gas hydrate production testing locations on the Alaska North Slope

    USGS Publications Warehouse

    Collett, Timothy S.; Boswell, Ray; Lee, Myung W.; Anderson, Brian J.; Rose, Kelly K.; Lewis, Kristen A.

    2012-01-01

    The results of short-duration formation tests in northern Alaska and Canada have further documented the energy-resource potential of gas hydrates and have justified the need for long-term gas-hydrate-production testing. Additional data acquisition and long-term production testing could improve the understanding of the response of naturally occurring gas hydrate to depressurization-induced or thermal-, chemical-, or mechanical-stimulated dissociation of gas hydrate into producible gas. The Eileen gashydrate accumulation located in the Greater Prudhoe Bay area in northern Alaska has become a focal point for gas-hydrate geologic and production studies. BP Exploration (Alaska) Incorporated and ConocoPhillips have each established research partnerships with the US Department of Energy to assess the production potential of gas hydrates in northern Alaska. A critical goal of these efforts is to identify the most suitable site for production testing. A total of seven potential locations in the Prudhoe Bay, Kuparuk River, and Milne Point production units were identified and assessed relative to their suitability as a long-term gas-hydrate-production test sites. The test-site-assessment criteria included the analysis of the geologic risk associated with encountering reservoirs for gas-hydrate testing. The site-selection process also dealt with the assessment of the operational/logistical risk associated with each of the potential test sites. From this review, a site in the Prudhoe Bay production unit was determined to be the best location for extended gas-hydrate-production testing. The work presented in this report identifies the key features of the potential test site in the Greater Prudhoe Bay area and provides new information on the nature of gas-hydrate occurrence and the potential impact of production testing on existing infrastructure at the most favorable sites. These data were obtained from well-log analysis, geological correlation and mapping, and numerical

  8. 46 CFR 154.182 - Contiguous hull structure: Production weld test.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Contiguous hull structure: Production weld test. 154.182... Equipment Hull Structure § 154.182 Contiguous hull structure: Production weld test. If a portion of the contiguous hull structure is designed for a temperature colder than −34 °C (−30 °F) and is not part of...

  9. 46 CFR 154.182 - Contiguous hull structure: Production weld test.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 5 2013-10-01 2013-10-01 false Contiguous hull structure: Production weld test. 154.182... Equipment Hull Structure § 154.182 Contiguous hull structure: Production weld test. If a portion of the contiguous hull structure is designed for a temperature colder than −34 °C (−30 °F) and is not part of...

  10. 46 CFR 154.182 - Contiguous hull structure: Production weld test.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 5 2014-10-01 2014-10-01 false Contiguous hull structure: Production weld test. 154.182... Equipment Hull Structure § 154.182 Contiguous hull structure: Production weld test. If a portion of the contiguous hull structure is designed for a temperature colder than −34 °C (−30 °F) and is not part of...

  11. 75 FR 42315 - Third Party Testing for Certain Children's Products; Carpets and Rugs: Requirements for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-21

    ... February 9, 2009 (74 FR 6396); the stay applied to testing and certification of various products, including carpets and rugs. On December 28, 2009, the Commission published a notice in the Federal Register (74 FR... COMMISSION 16 CFR Parts 1630 and 1631 Third Party Testing for Certain Children's Products; Carpets and...

  12. 21 CFR 211.110 - Sampling and testing of in-process materials and drug products.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... PHARMACEUTICALS Production and Process Controls § 211.110 Sampling and testing of in-process materials and drug... production process, e.g., at commencement or completion of significant phases or after storage for long... 21 Food and Drugs 4 2010-04-01 2010-04-01 false Sampling and testing of in-process materials...

  13. 40 CFR 1045.301 - When must I test my production-line engines?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... require you to test production-line engines under this subpart, or under 40 CFR part 1068, subpart E, even... described in 40 CFR part 1068. Individual engines in families that pass these production-line testing requirements must also conform to all applicable regulations of this part and 40 CFR part 1068. (d) You may...

  14. 40 CFR 1045.301 - When must I test my production-line engines?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... require you to test production-line engines under this subpart, or under 40 CFR part 1068, subpart E, even... described in 40 CFR part 1068. Individual engines in families that pass these production-line testing requirements must also conform to all applicable regulations of this part and 40 CFR part 1068. (d) You may...

  15. 40 CFR 1045.301 - When must I test my production-line engines?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... require you to test production-line engines under this subpart, or under 40 CFR part 1068, subpart E, even... described in 40 CFR part 1068. Individual engines in families that pass these production-line testing requirements must also conform to all applicable regulations of this part and 40 CFR part 1068. (d) You may...

  16. 40 CFR 1045.301 - When must I test my production-line engines?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... require you to test production-line engines under this subpart, or under 40 CFR part 1068, subpart E, even... described in 40 CFR part 1068. Individual engines in families that pass these production-line testing requirements must also conform to all applicable regulations of this part and 40 CFR part 1068. (d) You may...

  17. High-Technology Companies Often Turn to Colleges for Confidential 'Beta Tests' of New Products.

    ERIC Educational Resources Information Center

    Turner, Judith Axler

    1988-01-01

    Beta testing--the process of trying a product in a real-world setting before releasing it commercially--exploits a natural interface between universities and high-technology industries. High-tech companies need confidential, real-world tests of new products, and universities are eager to get an early look at tomorrow's technology. (MLW)

  18. 40 CFR 1045.301 - When must I test my production-line engines?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... require you to test production-line engines under this subpart, or under 40 CFR part 1068, subpart E, even... described in 40 CFR part 1068. Individual engines in families that pass these production-line testing requirements must also conform to all applicable regulations of this part and 40 CFR part 1068. (d) You may...

  19. Welding III.

    ERIC Educational Resources Information Center

    Allegheny County Community Coll., Pittsburgh, PA.

    Instructional objectives and performance requirements are outlined in this course guide for Welding III, an advanced course in arc welding offered at the Community College of Allegheny County to provide students with the proficiency necessary for industrial certification. The course objectives, which are outlined first, specify that students will…

  20. 40 CFR Table 4 to Subpart III of... - Compliance Requirements for Slabstock Foam Production Affected Sources Complying With the Source...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 11 2010-07-01 2010-07-01 true Compliance Requirements for Slabstock Foam Production Affected Sources Complying With the Source-Wide Emission Limitation 4 Table 4 to... Complying With the Source-Wide Emission Limitation Emission point Emission point compliance option...