Sample records for productivity facility ispf

  1. Design and development of an IBM/VM menu system

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cazzola, D.J.

    1992-10-01

    This report describes a full screen menu system developed using IBM's Interactive System Productivity Facility (ISPF) and the REXX programming language. The software was developed for the 2800 IBM/VM Electrical Computer Aided Design (ECAD) system. The system was developed to deliver electronic drawing definitions to a corporate drawing release system. Although this report documents the status of the menu system when it was retired, the methodologies used and the requirements defined are very applicable to replacement systems.

  2. Design and development of an IBM/VM menu system

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cazzola, D.J.

    1992-10-01

    This report describes a full screen menu system developed using IBM`s Interactive System Productivity Facility (ISPF) and the REXX programming language. The software was developed for the 2800 IBM/VM Electrical Computer Aided Design (ECAD) system. The system was developed to deliver electronic drawing definitions to a corporate drawing release system. Although this report documents the status of the menu system when it was retired, the methodologies used and the requirements defined are very applicable to replacement systems.

  3. Cytidine derivatives as IspF inhibitors of Burkolderia pseudomallei

    PubMed Central

    Zhang, Zheng; Jakkaraju, Sriram; Blain, Joy; Gogol, Kenneth; Zhao, Lei; Hartley, Robert C.; Karlsson, Courtney A.; Staker, Bart L.; Stewart, Lance J.; Myler, Peter J.; Clare, Michael; Begley, Darren W.; Horn, James R.; Hagen, Timothy J

    2013-01-01

    Published biological data suggest that the methyl erythritol phosphate (MEP) pathway, a non-mevalonate isoprenoid biosynthetic pathway, is essential for certain bacteria and other infectious disease organisms. One highly conserved enzyme in the MEP pathway is 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (IspF). Fragment-bound complexes of IspF from Burkholderia pseudomallei were used to design and synthesize a series of molecules linking the cytidine moiety to different zinc pocket fragment binders. Testing by surface plasmon resonance (SPR) found one molecule in the series to possess binding affinity equal to that of cytidine diphosphate, despite lacking any metal-coordinating phosphate groups. Close inspection of the SPR data suggest different binding stoichiometries between IspF and test compounds. Crystallographic analysis shows important variations between the binding mode of one synthesized compound and the pose of the bound fragment from which it was designed. The binding modes of these molecules add to our structural knowledge base for IspF and suggest future refinements in this compound series. PMID:24157367

  4. Transforaminal Lumbar Interbody Fusion with Rigid Interspinous Process Fixation: A Learning Curve Analysis of a Surgeon Team's First 74 Cases.

    PubMed

    Doherty, Patrick; Welch, Arthur; Tharpe, Jason; Moore, Camille; Ferry, Chris

    2017-05-30

    Studies have shown that a significant learning curve may be associated with adopting minimally invasive transforaminal lumbar interbody fusion (MIS TLIF) with bilateral pedicle screw fixation (BPSF). Accordingly, several hybrid TLIF techniques have been proposed as surrogates to the accepted BPSF technique, asserting that less/fewer fixation(s) or less disruptive fixation may decrease the learning curve while still maintaining the minimally disruptive benefits. TLIF with interspinous process fixation (ISPF) is one such surrogate procedure. However, despite perceived ease of adaptability given the favorable proximity of the spinous processes, no evidence exists demonstrating whether or not the technique may possess its own inherent learning curve. The purpose of this study was to determine whether an intraoperative learning curve for one- and two-level TLIF + ISPF may exist for a single lead surgeon. Seventy-four consecutive patients who received one- or two-Level TLIF with rigid ISPF by a single lead surgeon were retrospectively reviewed. It was the first TLIF + ISPF case series for the lead surgeon. Intraoperative blood loss (EBL), hospitalization length-of-stay (LOS), fluoroscopy time, and postoperative complications were collected. EBL, LOS, and fluoroscopy time were modeled as a function of case number using multiple linear regression methods. A change point was included in each model to allow the trajectory of the outcomes to change during the duration of the case series. These change points were determined using profile likelihood methods. Models were fit using the maximum likelihood estimates for the change points. Age, sex, body mass index (BMI), and the number of treated levels were included as covariates. EBL, LOS, and fluoroscopy time did not significantly differ by age, sex, or BMI (p ≥ 0.12). Only EBL differed significantly by the number of levels (p = 0.026). The case number was not a significant predictor of EBL, LOS, or fluoroscopy time (p ≥ 0.21). At the time of data collection (mean time from surgery: 13.3 months), six patients had undergone revision due to interbody migration. No ISPF device complications were observed. Study outcomes support the ideal that TLIF + ISPF can be a readily adopted procedure without a significant intraoperative learning curve. However, the authors emphasize that further assessment of long-term healing outcomes is essential in fully characterizing both the efficacy and the indication learning curve for the TLIF + ISPF technique.

  5. A structure-based approach to ligand discovery for 2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase: a target for antimicrobial therapy.

    PubMed

    Ramsden, Nicola L; Buetow, Lori; Dawson, Alice; Kemp, Lauris A; Ulaganathan, Venkatsubramanian; Brenk, Ruth; Klebe, Gerhard; Hunter, William N

    2009-04-23

    The nonmevalonate route to isoprenoid biosynthesis is essential in Gram-negative bacteria and apicomplexan parasites. The enzymes of this pathway are absent from mammals, contributing to their appeal as chemotherapeutic targets. One enzyme, 2C-methyl-d-erythritol-2,4-cyclodiphosphate synthase (IspF), has been validated as a target by genetic approaches in bacteria. Virtual screening against Escherichia coli IspF (EcIspF) was performed by combining a hierarchical filtering methodology with molecular docking. Docked compounds were inspected and 10 selected for experimental validation. A surface plasmon resonance assay was developed and two weak ligands identified. Crystal structures of EcIspF complexes were determined to support rational ligand development. Cytosine analogues and Zn(2+)-binding moieties were characterized. One of the putative Zn(2+)-binding compounds gave the lowest measured K(D) to date (1.92 +/- 0.18 muM). These data provide a framework for the development of IspF inhibitors to generate lead compounds of therapeutic potential against microbial pathogens.

  6. Intercomparison of Groundwater Flow Monitoring Technologies at Site OU 1, Former Fort Ord, California

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Daley, P F; Jantos, J; Pedler, W H

    2005-09-20

    This report presents an intercomparison of three groundwater flow monitoring technologies at a trichloroethylene (TCE) groundwater plume at Operational Unit 1 (OU 1) adjacent to the former Fritzsche Army Airfield at the former Fort Ord Army Base, located on Monterey Bay in northern Monterey County, California. Soil and groundwater at this site became contaminated by fuels and solvents that were burned on a portion of OU 1 called the Fire Drill Area (FDA) as part of firefighter training from 1962 and 1985. Cont Contamination is believed to be restricted to the unconfined A-aquifer, where water is reached at a depthmore » of approximately 60 to 80 feet below the ground surface; the aquifer is from 15 to 20 feet in thickness, and is bounded below by a dense clay layer, the Salinas Valley Aquitard. Soil excavation and bioremediation were initiated at the site of fire training activities in the late 1980s. Since that time a pump-and-treat operation has been operated close to the original area of contamination, and this system has been largely successful at reducing groundwater contamination in this source area. However, a trichloroethylene (TCE) groundwater plume extends approximately 3000 ft (900 m) to the northwest away from the FDA. In this report, we have augmented flow monitoring equipment permanently installed in an earlier project (Oldenburg et al., 2002) with two additional flow monitoring devices that could be deployed in existing monitoring wells, in an effort to better understand their performance in a nearly ideal, homogeneous sand aquifer, that we expected would exhibit laminar groundwater flow owing to the site's relatively simple hydrogeology. The three flow monitoring tools were the Hydrotechnics{reg_sign} In In-Situ Permeable Flow Sensor (ISPFS), the RAS Integrated Subsurface Evaluation Hydrophysical Logging tool (HPL), and the Lawrence Livermore National Laboratory Scanning Colloidal Borescope Flow Meter (SCBFM). All three devices produce groundwater flow velocity measurements, and the ISPFS and SCBFM systems also gene generate flow direction rate estimates. The ISPFS probes are permanently installed and are non-retrievable, but produce long-term records with essentially no operator intervention or maintenance. The HPL and SCBFM systems are lightweight, portable logging devices that employ recording of electrical conductivity changes in wells purged with deionized water (HPL), or imaging of colloidal particles traversing the borehole (SCBFM) as the physical basis for estimating the velocity of groundwater flow through monitoring wells. All three devices gave estimates of groundwater velocity that were in reasonable agreement. However, although the ISPFS produced groundwater azimuth data that correlated well with conventional conductivity and gradient analyses of the groundwater flow field, the SCBFM direction data were in poor agreement. Further research into the reasons for this lack of correlation would seem to be warranted, given the ease of deployment of this tool in existing conventional monitoring wells, and its good agreement with the velocity estimates of the other technologies examined.« less

  7. Coregulation of Terpenoid Pathway Genes and Prediction of Isoprene Production in Bacillus subtilis Using Transcriptomics.

    PubMed

    Hess, Becky M; Xue, Junfeng; Markillie, Lye Meng; Taylor, Ronald C; Wiley, H Steven; Ahring, Birgitte K; Linggi, Bryan

    2013-01-01

    The isoprenoid pathway converts pyruvate to isoprene and related isoprenoid compounds in plants and some bacteria. Currently, this pathway is of great interest because of the critical role that isoprenoids play in basic cellular processes, as well as the industrial value of metabolites such as isoprene. Although the regulation of several pathway genes has been described, there is a paucity of information regarding system level regulation and control of the pathway. To address these limitations, we examined Bacillus subtilis grown under multiple conditions and determined the relationship between altered isoprene production and gene expression patterns. We found that with respect to the amount of isoprene produced, terpenoid genes fall into two distinct subsets with opposing correlations. The group whose expression levels positively correlated with isoprene production included dxs, which is responsible for the commitment step in the pathway, ispD, and two genes that participate in the mevalonate pathway, yhfS and pksG. The subset of terpenoid genes that inversely correlated with isoprene production included ispH, ispF, hepS, uppS, ispE, and dxr. A genome-wide partial least squares regression model was created to identify other genes or pathways that contribute to isoprene production. These analyses showed that a subset of 213 regulated genes was sufficient to create a predictive model of isoprene production under different conditions and showed correlations at the transcriptional level. We conclude that gene expression levels alone are sufficiently informative about the metabolic state of a cell that produces increased isoprene and can be used to build a model that accurately predicts production of this secondary metabolite across many simulated environmental conditions.

  8. Coregulation of Terpenoid Pathway Genes and Prediction of Isoprene Production in Bacillus subtilis Using Transcriptomics

    PubMed Central

    Hess, Becky M.; Xue, Junfeng; Markillie, Lye Meng; Taylor, Ronald C.; Wiley, H. Steven; Ahring, Birgitte K.; Linggi, Bryan

    2013-01-01

    The isoprenoid pathway converts pyruvate to isoprene and related isoprenoid compounds in plants and some bacteria. Currently, this pathway is of great interest because of the critical role that isoprenoids play in basic cellular processes, as well as the industrial value of metabolites such as isoprene. Although the regulation of several pathway genes has been described, there is a paucity of information regarding system level regulation and control of the pathway. To address these limitations, we examined Bacillus subtilis grown under multiple conditions and determined the relationship between altered isoprene production and gene expression patterns. We found that with respect to the amount of isoprene produced, terpenoid genes fall into two distinct subsets with opposing correlations. The group whose expression levels positively correlated with isoprene production included dxs, which is responsible for the commitment step in the pathway, ispD, and two genes that participate in the mevalonate pathway, yhfS and pksG. The subset of terpenoid genes that inversely correlated with isoprene production included ispH, ispF, hepS, uppS, ispE, and dxr. A genome-wide partial least squares regression model was created to identify other genes or pathways that contribute to isoprene production. These analyses showed that a subset of 213 regulated genes was sufficient to create a predictive model of isoprene production under different conditions and showed correlations at the transcriptional level. We conclude that gene expression levels alone are sufficiently informative about the metabolic state of a cell that produces increased isoprene and can be used to build a model that accurately predicts production of this secondary metabolite across many simulated environmental conditions. PMID:23840410

  9. Coregulation of terpenoid pathway genes and prediction of isoprene production in Bacillus subtilis using transcriptomics

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hess, Becky M.; Xue, Junfeng; Markillie, Lye Meng

    2013-06-19

    The isoprenoid pathway converts pyruvate to isoprene and related isoprenoid compounds in plants and some bacteria. Currently, this pathway is of great interest because of the critical role that isoprenoids play in basic cellular processes as well as the industrial value of metabolites such as isoprene. Although the regulation of several pathway genes has been described, there is a paucity of information regarding the system level regulation and control of the pathway. To address this limitation, we examined Bacillus subtilis grown under multiple conditions and then determined the relationship between altered isoprene production and the pattern of gene expression. Wemore » found that terpenoid genes appeared to fall into two distinct subsets with opposing correlations with respect to the amount of isoprene produced. The group whose expression levels positively correlated with isoprene production included dxs, the gene responsible for the commitment step in the pathway, as well as ispD, and two genes that participate in the mevalonate pathway, yhfS and pksG. The subset of terpenoid genes that inversely correlated with isoprene production included ispH, ispF, hepS, uppS, ispE, and dxr. A genome wide partial least squares regression model was created to identify other genes or pathways that contribute to isoprene production. This analysis showed that a subset of 213 regulated genes was sufficient to create a predictive model of isoprene production under different conditions and showed correlations at the transcriptional level. We conclude that gene expression levels alone are sufficiently informative about the metabolic state of a cell that produces increased isoprene and can be used to build a model which accurately predicts production of this secondary metabolite across many simulated environmental conditions.« less

  10. The CDC SHIELD Orange County Project – Baseline Multi Drug-Resistant Organism (MDRO) Prevalence in a Southern California Region

    PubMed Central

    Singh, Raveena D; Jernigan, John A; Slayton, Rachel B; Stone, Nimalie D; McKinnell, James A; Miller, Loren G; Kleinman, Ken; Heim, Lauren; Dutciuc, Tabitha D; Estevez, Marlene; Gussin, Gabrielle; Chang, Justin; Peterson, Ellena M; Evans, Kaye D; Lee, Bruce Y; Mueller, Leslie E; Bartsch, Sarah M; Zahn, Matthew; Janssen, Lynn; Weinstein, Robert A; Hayden, Mary K; Gohil, Shruti K; Park, Steven; Tam, Steven; Saavedra, Raheeb; Yamaguchi, Stacey; Custodio, Harold; Nguyen, Jenny; Tjoa, Thomas; He, Jiayi; O’Donnell, Kathleen; Coady, Micaela H; Platt, Richard; Huang, Susan S

    2017-01-01

    Abstract Background MDROs can spread between hospitals, nursing homes (NH), and long-term acute care facilities (LTACs) via shared patients. SHIELD OC is a regional decolonization collaborative involving 38 of 104 countywide adult facilities identified by their high degree of direct and indirect patient sharing with one another. We report baseline MDRO prevalence in these facilities. Methods Adult patients in 38 facilities (17 hospitals, 18 NHs, 3 LTACs) underwent point-prevalence screening between September 2016–April 2017 for MRSA, VRE, ESBL, and CRE using nares, skin (axilla/groin), and peri-rectal swabs. In NHs and LTACs, residents were randomly selected until 50 sets of swabs were obtained. Swabbing in hospitals involved all patients in contact precautions. An additional set of swabs were also performed for all LTAC admissions from November 2016–February 2017. Results The overall prevalence of any MDRO among patients was 64% (44%–88%) in NHs, 80% (range 72%–86%) in LTACs, and 64% (54–84%) in hospitals (contact precaution patients) (Table 1). Only 25%, 64%, and 81% of patients were already known to harbor an MDRO in NHs, LTACs, and hospitals, respectively. Known MDRO patients also harbored another MDRO 49%, 63%, and 34% of the time for NHs, LTACs, and hospitals, respectively. In LTACs, MDRO point prevalence was 38% higher than the usual admission prevalence (65% higher for MRSA, 34% higher for VRE, 95% higher for ESBL, and 50% higher for CRE). Conclusion MDRO carriage in highly inter-connected NHs and LTACs was widespread, rivaling that found in hospitalized patients on contact precautions. MRSA, VRE, and ESBL carriage far outnumbered CRE carriage. A history of MDRO was insensitive for identifying MDRO carriers, and many patients carried multiple MDROs. The extensive MDRO burden and transmission in long-term care settings suggests that regional MDRO prevention efforts must include MDRO control in long-term care facilities. Disclosures R. D. Singh, Sage Products: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; 3M: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Xttrium Laboratories: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Clorox: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; J. A. McKinnell, Sage Products: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; 3M: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Xttrium: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Clorox: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; L. G. Miller, Sage Products: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Xttrium: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Clorox: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; 3M: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; K. Kleinman, Sage Products: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Clorox: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Xttrium Laboratories: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Molnlycke: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; 3M: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; L. Heim, Clorox: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Sage Products: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Xttrium: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; 3M: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; T. D. Dutciuc, Sage Products: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Xttrium: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Clorox: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; 3M: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; M. Estevez, Sage Products: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Xttrium: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Clorox: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; 3M: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; G. Gussin, Sage Products: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Clorox: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Xttrium Laboratories: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; L’Oreal: Consultant, Consulting fee; J. Chang, Sage Products: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Xttrium Laboratories: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Clorox: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; 3M: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; E. M. Peterson, Sage Products: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Xttrium Laboratories: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Clorox: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; B. Y. Lee, GSK: Consultant, Consulting fee; R. A. Weinstein, Sage Products: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Molnlycke: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Clorox: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; OpGen Company: Study support, Provided services at no charge; M. K. Hayden, Sage Products: Receipt of contributed product, Sage is contributing product to healthcare facilities participating in a regional collaborative on which I am a co-investigator. Neither I nor my hospital receive product.; Clorox: Receipt of contributed product, Research support; CDC: Grant Investigator and Receipt of contributed product, Research grant; Molnlycke: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; OpGen Company: Study support, Provided services at no charge for studies; S. K. Gohil, Sage Products: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Xttrium Laboratories: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Clorox: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; S. Park, Sage Products: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Clorox: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Xttrium Laboratories: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; S. Tam, Sage Products: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; 3M: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Xttrium Laboratories: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Clorox: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; R. Saavedra, Sage Products: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Xttrium Laboratories: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Clorox: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; S. Yamaguchi, Sage Products: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Xttrium Laboratories: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Clorox: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; H. Custodio, Xttrium Laboratories: Study coordination, Conducting studies in healthcare facilities that are receiving contributed product; Sage Products: Study coordination, Conducting studies in healthcare facilities that are receiving contributed product; Clorox: Study coordination, Conducting studies in healthcare facilities that are receiving contributed product; J. Nguyen, Sage Products: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Xttrium Laboratories: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Clorox: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; T. Tjoa, Sage Products: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Xttrium Laboratories: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Clorox: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; 3M: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; J. He, Sage Products: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Xttrium Laboratories: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Clorox: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; 3M: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; M. H. Coady, Sage Products: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Molnlycke: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Xttrium Laboratories: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Clorox: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; R. Platt, Sage Products: Receipt of contributed product, Conducting clinical studies in which participating healthcare facilities are receiving contributed product; Xttrium Laboratories: Receipt of contributed product, Conducting clinical studies in which participating healthcare facilities are receiving contributed product; Clorox: Receipt of contributed product, Conducting clinical studies in which participating healthcare facilities are receiving contributed product; receive research funds from Clorox, but Clorox has no role in the design; Molnlycke: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; S. S. Huang, Sage Products: Receipt of contributed product, Conducting studies in which participating healthcare facilities are receiving contributed product (no contribution in submitted abstract), Participating healthcare facilities in my studies received contributed product; Xttrium Laboratories: Receipt of contributed product, Conducting studies in which participating healthcare facilities are receiving contributed product (no contribution in submitted abstract), Participating healthcare facilities in my studies received contributed product; Clorox: Receipt of contributed product, Conducting studies in which participating healthcare facilities are receiving contributed product (no contribution in submitted abstract), Participating healthcare facilities in my studies received contributed product; 3M: Receipt of contributed product, Conducting studies in which participating healthcare facilities are receiving contributed product (no contribution in submitted abstract), Participating healthcare facilities in my studies received contributed product; Molnlycke: Receipt of contributed product, Conducting studies in which participating healthcare facilities are receiving contributed product (no contribution in submitted abstract), Participating healthcare facilities in my studies received contributed product

  11. When a Home is Not a Home: MultiDrug-Resistant Organism (MDRO) Colonization and Environmental Contamination in 28 Nursing Homes (NHs)

    PubMed Central

    McKinnell, James A; Miller, Loren; Singh, Raveena D; Mendez, Job; Franco, Ryan; Gussin, Gabrielle; Chang, Justin; Dutciuc, Tabitha D; Saavedra, Raheeb; Kleinman, Ken; Peterson, Ellena M; Evans, Kaye D; Heim, Lauren; Miner, Aaron; Estevez, Marlene; Custodio, Harold; Yamaguchi, Stacey; Nguyen, Jenny; Varasteh, Alex; Launer, Bryn; Agrawal, Shalini; Tjoa, Thomas; He, Jiayi; Park, Steven; Tam, Steven; Gohil, Shruti K; Stone, Nimalie D; Steinberg, Karl; Montgomery, Jocelyn; Beecham, Nancy; Huang, Susan S

    2017-01-01

    Abstract Background The majority of healthcare-associated infections due to MDROs occur in the post-discharge setting. Understanding MDRO spread and containment in NHs can help identify infection prevention activities needed to care for vulnerable patients in a medical home setting. Methods We conducted a baseline point prevalence study of MDRO colonization in residents of 28 Southern California NHs participating in a decolonization trial. In Fall 2016, residents were randomly sampled to obtain a set of 50 nares and skin (axilla/groin) swabs from each NH. Nasal swabs were processed for MRSA and skin swabs were processed for MRSA, VRE, ESBL, and CRE. In addition, environmental swabs were collected from high touch objects in resident rooms (bedrail, call button/TV remote, door knobs, light switch, bathroom) and common areas (nursing station, table, chair, railing, and drinking fountain). Results A total of 2,797 body swabs were obtained from 1400 residents. Overall, 48.6% (N = 680) of residents harbored MDROs. MRSA was found in 37% of residents (29.5% nares, 24.4% skin), followed by ESBL in 16% (Table 1). Resident MDRO status was only known for 11% of MRSA (59/518), 18% ESBL (40/228), 4% VRE (4/99), and none of the CRE (0/13) carriers. Colonization did not differ between long stay (48.8%, 534/1094) vs. post-acute (47.7%, 146/306) residents (P = NS), but bedbound residents were more likely to be MDRO colonized (58.7%, 182/310) vs. ambulatory residents (45.7%, 497/1088, P < 0.001). A total of 560 environmental swabs were obtained with 93% of common areas and 74% of resident rooms having an MDRO+ object with an average of 2.5 and 1.9 objects found to be contaminated (Table 2). Conclusion One in two NH residents are colonized with MDROs, which is largely unknown to the facility. MDRO carriage is associated with total care needs, but not long stay status. Environmental contamination in resident rooms and common areas is common. The burden of MDRO colonization and contamination is sufficiently high that universal strategies to reduce colonization and transmission are warranted. Disclosures J. A. McKinnell, Allergan: Research Contractor, Scientific Advisor and Speaker’s Bureau, Consulting fee, Research support and Speaker honorarium; Achaogen: Research Contractor, Scientific Advisor and Shareholder, Research support; Cempra: Research Contractor and Scientific Advisor, Research support; Theravance: Research Contractor, Research support; Science 37: Research Contractor, Salary; Expert Stewardship, LLC: Board Member and Employee, Salary; Thermo Fisher: Scientific Advisor, Salary; 3M: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Clorox: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Sage Products: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Xttrium Laboratories: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; L. Miller, 3M: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Clorox: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Sage Products: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Xttrium Laboratories: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; R. D. Singh, Sage Products: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; 3M: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Xttrium Laboratories: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Clorox: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; J. Mendez, Clorox: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Sage Products: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Xttrium Laboratories: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; R. Franco, Clorox: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Sage Products: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Xttrium Laboratories: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; G. Gussin, Sage Products: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Clorox: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Xttrium Laboratories: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; L’Oreal: Consultant, Consulting fee; J. Chang, Sage Products: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Xttrium Laboratories: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Clorox: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; 3M: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; T. D. Dutciuc, Sage Products: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Xttrium: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Clorox: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; 3M: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; R. Saavedra, Sage Products: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Xttrium Laboratories: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Clorox: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; K. Kleinman, Sage Products: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Clorox: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Xttrium Laboratories: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Molnlycke: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; 3M: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; E. M. Peterson, Clorox: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Sage Products: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Xttrium Laboratories: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; L. Heim, Clorox: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Sage Products: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Xttrium: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; 3M: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; A. Miner, Clorox: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Sage Products: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Xttrium Laboratories: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; M. Estevez, Sage Products: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Xttrium: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Clorox: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; 3M: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; H. Custodio, Xttrium Laboratories: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Sage Products: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Clorox: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; S. Yamaguchi, Sage Products: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Xttrium Laboratories: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Clorox: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; J. Nguyen, Sage Products: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Xttrium Laboratories: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Clorox: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; A. Varasteh, Clorox: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Sage Product: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Xttrium Laboratories: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; B. Launer, 3M: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Clorox: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Sage Products: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Xttrium Laboratories: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; S. Agrawal, Clorox: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Sage Products: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Xttrium Laboratories: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; T. Tjoa, Sage Products: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Xttrium Laboratories: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Clorox: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; 3M: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; J. He, Sage Products: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Xttrium Laboratories: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Clorox: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; 3M: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; S. Park, Sage Products: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Clorox: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Xttrium Laboratories: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; S. Tam, Sage Products: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; 3M: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Xttrium Laboratories: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Clorox: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; S. K. Gohil, Sage Products: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Xttrium Laboratories: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Clorox: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; S. S. Huang, Sage Products: Receipt of contributed product, Conducting studies in which participating healthcare facilities are receiving contributed product (no contribution in submitted abstract), Participating healthcare facilities in my studies received contributed product; Xttrium Laboratories: Receipt of contributed product, Conducting studies in which participating healthcare facilities are receiving contributed product (no contribution in submitted abstract), Participating healthcare facilities in my studies received contributed product; Clorox: Receipt of contributed product, Conducting studies in which participating healthcare facilities are receiving contributed product (no contribution in submitted abstract), Participating healthcare facilities in my studies received contributed product; 3M: Receipt of contributed product, Conducting studies in which participating healthcare facilities are receiving contributed product (no contribution in submitted abstract), Participating healthcare facilities in my studies received contributed product; Molnlycke: Receipt of contributed product, Conducting studies in which participating healthcare facilities are receiving contributed product (no contribution in submitted abstract), Participating healthcare facilities in my studies received contributed product

  12. 78 FR 55993 - Revisions to Reporting and Recordkeeping Requirements, and Proposed Confidentiality...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-11

    ... facilities. Adipic Acid Production 325199 Adipic acid manufacturing facilities. Aluminum Production 331312 Primary aluminum production facilities Ammonia Manufacturing 325311 Anhydrous and aqueous ammonia production facilities. Cement Production 327310 Portland Cement manufacturing plants. Ferroalloy Production...

  13. 7 CFR Appendix C to Subpart E of... - Guidelines for Loan Guarantees for Alcohol Fuel Production Facilities

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... beverage purposes, is manufactured from biomass. (2) The alcohol production facility includes all... Production Facilities C Appendix C to Subpart E of Part 1980 Agriculture Regulations of the Department of...—Guidelines for Loan Guarantees for Alcohol Fuel Production Facilities (1) Alcohol production facility. An...

  14. 7 CFR Appendix C to Subpart E of... - Guidelines for Loan Guarantees for Alcohol Fuel Production Facilities

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... beverage purposes, is manufactured from biomass. (2) The alcohol production facility includes all... Production Facilities C Appendix C to Subpart E of Part 1980 Agriculture Regulations of the Department of...—Guidelines for Loan Guarantees for Alcohol Fuel Production Facilities (1) Alcohol production facility. An...

  15. 44 CFR 331.5 - Production facilities.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 44 Emergency Management and Assistance 1 2011-10-01 2011-10-01 false Production facilities. 331.5... AND FACILITIES IN LABOR SURPLUS AREAS § 331.5 Production facilities. All Federal departments and... production facilities, including expansion, to the extent that such selection is consistent with existing law...

  16. 6 CFR 37.43 - Physical security of DMV production facilities.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 6 Domestic Security 1 2012-01-01 2012-01-01 false Physical security of DMV production facilities... Identification Card Production Facilities § 37.43 Physical security of DMV production facilities. (a) States must ensure the physical security of facilities where driver's licenses and identification cards are produced...

  17. Sterol Composition and Biosynthetic Genes of Vitrella brassicaformis, a Recently Discovered Chromerid: Comparison to Chromera velia and Phylogenetic Relationship with Apicomplexan Parasites.

    PubMed

    Khadka, Manoj; Salem, Mohamed; Leblond, Jeffrey D

    2015-01-01

    Vitrella brassicaformis is the second discovered species in the Chromerida, and first in the family Vitrellaceae. Chromera velia, the first discovered species, forms an independent photosynthetic lineage with V. brassicaformis, and both are closely related to peridinin-containing dinoflagellates and nonphotosynthetic apicomplexans; both also show phylogenetic closeness with red algal plastids. We have utilized gas chromatography/mass spectrometry to identify two free sterols, 24-ethylcholest-5-en-3β-ol, and a minor unknown sterol which appeared to be a C(28:4) compound. We have also used RNA Seq analysis to identify seven genes found in the nonmevalonate/methylerythritol pathway (MEP) for sterol biosynthesis. Subsequent genome analysis of V. brassicaformis showed the presence of two mevalonate (MVA) pathway genes, though the genes were not observed in the transcriptome analysis. Transcripts from four genes (dxr, ispf, ispd, and idi) were selected and translated into proteins to study the phylogenetic relationship of sterol biosynthesis in V. brassicaformis and C. velia to other groups of algae and apicomplexans. On the basis of our genomic and transcriptomic analyses, we hypothesize that the MEP pathway was the primary pathway that apicomplexans used for sterol biosynthesis before they lost their sterol biosynthesis ability, although contribution of the MVA pathway cannot be discounted. © 2015 The Author(s) Journal of Eukaryotic Microbiology © 2015 International Society of Protistologists.

  18. 40 CFR 63.11166 - What General Provisions apply to primary beryllium production facilities?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Primary Nonferrous Metals Area Sources-Zinc, Cadmium, and Beryllium Primary Beryllium Production Facilities § 63.11166 What General Provisions apply to primary beryllium production facilities? (a) You must... primary beryllium production facilities? 63.11166 Section 63.11166 Protection of Environment ENVIRONMENTAL...

  19. 18 CFR 292.204 - Criteria for qualifying small power production facilities.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY REGULATIONS UNDER THE PUBLIC UTILITY REGULATORY... production capacity of any other small power production facilities that use the same energy resource, are... production facilities within one mile of such facilities. (b) Fuel use. (1)(i) The primary energy source of...

  20. 40 CFR 63.11164 - What General Provisions apply to primary zinc production facilities?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... primary zinc production facilities? 63.11164 Section 63.11164 Protection of Environment ENVIRONMENTAL... Primary Nonferrous Metals Area Sources-Zinc, Cadmium, and Beryllium Primary Zinc Production Facilities § 63.11164 What General Provisions apply to primary zinc production facilities? (a) If you own or...

  1. 40 CFR 63.11164 - What General Provisions apply to primary zinc production facilities?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... primary zinc production facilities? 63.11164 Section 63.11164 Protection of Environment ENVIRONMENTAL... Primary Nonferrous Metals Area Sources-Zinc, Cadmium, and Beryllium Primary Zinc Production Facilities § 63.11164 What General Provisions apply to primary zinc production facilities? (a) If you own or...

  2. 76 FR 30781 - Confidentiality Determinations for Data Required Under the Mandatory Greenhouse Gas Reporting...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-26

    .......... 325199 Adipic acid manufacturing facilities. Aluminum Production 331312 Primary Aluminum production.... Cement Production 327310 Portland Cement manufacturing plants. Ferroalloy Production........ 331112 Ferroalloys manufacturing facilities. Glass Production 327211 Flat glass manufacturing facilities. 327213...

  3. 40 CFR 122.24 - Concentrated aquatic animal production facilities (applicable to State NPDES programs, see § 123...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS EPA ADMINISTERED PERMIT PROGRAMS: THE... animal production facility means a hatchery, fish farm, or other facility which meets the criteria in... any warm or cold water aquatic animal production facility as a concentrated aquatic animal production...

  4. 40 CFR 122.24 - Concentrated aquatic animal production facilities (applicable to State NPDES programs, see § 123...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS EPA ADMINISTERED PERMIT PROGRAMS: THE... animal production facility means a hatchery, fish farm, or other facility which meets the criteria in... any warm or cold water aquatic animal production facility as a concentrated aquatic animal production...

  5. 18 CFR 292.602 - Exemption to qualifying facilities from the Public Utility Holding Company Act of 2005 and...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... PRODUCTION AND COGENERATION Exemption of Qualifying Small Power Production Facilities and Cogeneration... small power production facility with a power production capacity over 30 megawatts if such facility produces electric energy solely by the use of biomass as a primary energy source. (b) Exemption from the...

  6. 18 CFR 292.602 - Exemption to qualifying facilities from the Public Utility Holding Company Act of 2005 and...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... PRODUCTION AND COGENERATION Exemption of Qualifying Small Power Production Facilities and Cogeneration... small power production facility with a power production capacity over 30 megawatts if such facility produces electric energy solely by the use of biomass as a primary energy source. (b) Exemption from the...

  7. 18 CFR 292.602 - Exemption to qualifying facilities from the Public Utility Holding Company Act of 2005 and...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... PRODUCTION AND COGENERATION Exemption of Qualifying Small Power Production Facilities and Cogeneration... small power production facility with a power production capacity over 30 megawatts if such facility produces electric energy solely by the use of biomass as a primary energy source. (b) Exemption from the...

  8. 18 CFR 292.208 - Special requirements for hydroelectric small power production facilities located at a new dam or...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... for hydroelectric small power production facilities located at a new dam or diversion. 292.208 Section... requirements for hydroelectric small power production facilities located at a new dam or diversion. (a) A hydroelectric small power production facility that impounds or diverts the water of a natural watercourse by...

  9. 18 CFR 292.208 - Special requirements for hydroelectric small power production facilities located at a new dam or...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... for hydroelectric small power production facilities located at a new dam or diversion. 292.208 Section... requirements for hydroelectric small power production facilities located at a new dam or diversion. (a) A hydroelectric small power production facility that impounds or diverts the water of a natural watercourse by...

  10. 18 CFR 292.208 - Special requirements for hydroelectric small power production facilities located at a new dam or...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... for hydroelectric small power production facilities located at a new dam or diversion. 292.208 Section... requirements for hydroelectric small power production facilities located at a new dam or diversion. (a) A hydroelectric small power production facility that impounds or diverts the water of a natural watercourse by...

  11. 7 CFR Appendix C to Subpart E of... - Guidelines for Loan Guarantees for Alcohol Fuel Production Facilities

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... facilities necessary for the production and storage of alcohol and the processing of the by-products of alcohol production. The intent is to limit the alcohol and by-products processing facilities to those... alcohol or by-products in another manufacturing process, are not considered part of the alcohol production...

  12. 10 CFR 50.22 - Class 103 licenses; for commercial and industrial facilities.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... facilities. 50.22 Section 50.22 Energy NUCLEAR REGULATORY COMMISSION DOMESTIC LICENSING OF PRODUCTION AND..., transfer, acquire, possess, or use a production or utilization facility for industrial or commercial purposes; Provided, however, That in the case of a production or utilization facility which is useful in...

  13. Northeast Oregon Hatchery Project, Final Siting Report.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Watson, Montgomery

    1995-03-01

    This report presents the results of site analysis for the Bonneville Power Administration Northeast Oregon Hatchery Project. The purpose of this project is to provide engineering services for the siting and conceptual design of hatchery facilities for the Bonneville Power Administration. The hatchery project consists of artificial production facilities for salmon and steelhead to enhance production in three adjacent tributaries to the Columbia River in northeast Oregon: the Grande Ronde, Walla Walla, and Imnaha River drainage basins. Facilities identified in the master plan include adult capture and holding facilities; spawning incubation, and early rearing facilities; full-term rearing facilities; and directmore » release or acclimation facilities. The evaluation includes consideration of a main production facility for one or more of the basins or several smaller satellite production facilities to be located within major subbasins. The historic and current distribution of spring and fall chinook salmon and steelhead was summarized for the Columbia River tributaries. Current and future production and release objectives were reviewed. Among the three tributaries, forty seven sites were evaluated and compared to facility requirements for water and space. Site screening was conducted to identify the sites with the most potential for facility development. Alternative sites were selected for conceptual design of each facility type. A proposed program for adult holding facilities, final rearing/acclimation, and direct release facilities was developed.« less

  14. 7 CFR 1424.10 - Succession and control of facilities and production.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 10 2014-01-01 2014-01-01 false Succession and control of facilities and production... § 1424.10 Succession and control of facilities and production. A person who obtains a facility that is... grant such request if it is determined that permitting such succession would serve the purposes of the...

  15. 7 CFR 1424.10 - Succession and control of facilities and production.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 10 2012-01-01 2012-01-01 false Succession and control of facilities and production... § 1424.10 Succession and control of facilities and production. A person who obtains a facility that is... grant such request if it is determined that permitting such succession would serve the purposes of the...

  16. 7 CFR 1424.10 - Succession and control of facilities and production.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 10 2013-01-01 2013-01-01 false Succession and control of facilities and production... § 1424.10 Succession and control of facilities and production. A person who obtains a facility that is... grant such request if it is determined that permitting such succession would serve the purposes of the...

  17. 7 CFR 1424.10 - Succession and control of facilities and production.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 10 2011-01-01 2011-01-01 false Succession and control of facilities and production... § 1424.10 Succession and control of facilities and production. A person who obtains a facility that is... grant such request if it is determined that permitting such succession would serve the purposes of the...

  18. 7 CFR 1424.10 - Succession and control of facilities and production.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Succession and control of facilities and production... § 1424.10 Succession and control of facilities and production. A person who obtains a facility that is... grant such request if it is determined that permitting such succession would serve the purposes of the...

  19. School Facilities in Arizona: An Examination of the Relationships between and among School Facilities Characteristics and Educational Outcomes.

    ERIC Educational Resources Information Center

    2000

    This report examines the relations between school design and student productivity and informs policy decisions. It contains three analytic sections: an analysis of school facilities characteristics and student productivity, a review of other research examining school facilities and student productivity, and an analysis of the need for school…

  20. 40 CFR 60.30d - Designated facilities.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 6 2010-07-01 2010-07-01 false Designated facilities. 60.30d Section... Acid Production Units § 60.30d Designated facilities. Sulfuric acid production units. The designated facility to which §§ 60.31d and 60.32d apply is each existing “sulfuric acid production unit” as defined in...

  1. Study of the impact of automation on productivity in bus-maintenance facilities. Final report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sumanth, D.J.; Weiss, H.J.; Adya, B.

    1988-12-01

    Whether or not the various types of automation and new technologies introduced in a bus-transit system really have an impact on productivity is the question addressed in the study. The report describes a new procedure of productivity measurement and evaluation for a county-transit system and provides an objective perspective on the impact of automation on productivity in bus maintenance facilities. The research objectives were: to study the impact of automation on total productivity in transit maintenance facilities; to develop and apply a methodology for measuring the total productivity of a Floridian transit maintenance facility (Bradenton-Manatee County bus maintenance facility whichmore » has been introducing automation since 1983); and to develop a practical step-by-step implementation scheme for the total productivity-based productivity measurement system that any bus manager can use. All 3 objectives were successfully accomplished.« less

  2. Analysis of Aquifer Response, Groundwater Flow, and PlumeEvolution at Site OU 1, Former Fort Ord, California

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jordan, Preston D.; Oldenburg, Curtis M.; Su, Grace W.

    2005-02-24

    This report presents a continuation from Oldenburg et al. (2002) of analysis of the hydrogeology, In-Situ Permeable Flow Sensor (ISPFS) results, aquifer response, and changes in the trichloroethylene (TCE) groundwater plume at Operational Unit 1 (OU 1) adjacent to the former Fritzsche Army Airfield at the former Fort Ord Army Base, located on Monterey Bay in northern Monterey County. Fuels and solvents were burned on a portion of OU 1 called the Fire Drill Area (FDA) during airport fire suppression training between 1962 and 1985. This activity resulted in soil and groundwater contamination in the unconfined A-aquifer. In the latemore » 1980's, soil excavation and bioremediation were successful in remediating soil contamination at the site. Shortly thereafter, a groundwater pump, treat, and recharge system commenced operation. This system has been largely successful at remediating groundwater contamination at the head of the groundwater plume. However, a trichloroethylene (TCE) groundwater plume extends approximately 3000 ft (900 m) to the northwest away from the FDA. In the analyses presented here, we augment our prior work (Oldenburg et al., 2002) with new information including treatment-system totalizer data, recent water-level and chemistry data, and data collected from new wells to discern trends in contaminant migration and groundwater flow that may be useful for ongoing remediation efforts. Some conclusions from the prior study have been modified based on these new analyses, and these are pointed out clearly in this report.« less

  3. 40 CFR 60.2030 - Who implements and enforces this subpart?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... qualifying small power production facility or cogeneration facility under § 60.2020(e) or (f) is combusting... qualifying small power production facility or cogeneration facility under § 60.2020(e) or (f) is combusting...

  4. 18 CFR 292.208 - Special requirements for hydroelectric small power production facilities located at a new dam or...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... for hydroelectric small power production facilities located at a new dam or diversion. 292.208 Section... 201 AND 210 OF THE PUBLIC UTILITY REGULATORY POLICIES ACT OF 1978 WITH REGARD TO SMALL POWER PRODUCTION AND COGENERATION Qualifying Cogeneration and Small Power Production Facilities § 292.208 Special...

  5. 18 CFR 292.208 - Special requirements for hydroelectric small power production facilities located at a new dam or...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... for hydroelectric small power production facilities located at a new dam or diversion. 292.208 Section... 201 AND 210 OF THE PUBLIC UTILITY REGULATORY POLICIES ACT OF 1978 WITH REGARD TO SMALL POWER PRODUCTION AND COGENERATION Qualifying Cogeneration and Small Power Production Facilities § 292.208 Special...

  6. 12 CFR 7.5002 - Furnishing of products and services by electronic means and facilities.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 1 2010-01-01 2010-01-01 false Furnishing of products and services by... products and services by electronic means and facilities. (a) Use of electronic means and facilities. A... a collection of links to web sites of third-party vendors, organized by-product type and made...

  7. 77 FR 64953 - Notice of Initiation and Preliminary Results of Antidumping Duty Changed Circumstances Review...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-24

    ... company's management, production facilities and customer/supplier relationships have not changed as a... in no significant changes to management, production facilities, supplier relationships, and customers... limited to, changes in: (1) Management; (2) production facilities; (3) supplier relationships; and (4...

  8. 40 CFR 63.5795 - How do I know if my reinforced plastic composites production facility is a new affected source or...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... composites production facility is a new affected source or an existing affected source? 63.5795 Section 63... for Hazardous Air Pollutants: Reinforced Plastic Composites Production What This Subpart Covers § 63.5795 How do I know if my reinforced plastic composites production facility is a new affected source or...

  9. The Influence of Process Equipment on the Properties of Suspension Plasma Sprayed Yttria-Stabilized Zirconia Coatings

    NASA Astrophysics Data System (ADS)

    Marr, Michael; Waldbillig, David; Kesler, Olivera

    2013-03-01

    Suspension plasma-sprayed YSZ coatings were deposited at lab-scale and production-type facilities to investigate the effect of process equipment on coating properties. The target application for these coatings is solid oxide fuel cell (SOFC) electrolytes; hence, dense microstructures with low permeability values were preferred. Both facilities had the same torch but different suspension feeding systems, torch robots, and substrate holders. The lab-scale facility had higher torch-substrate relative speeds compared with the production-type facility. On porous stainless steel substrates, permeabilities and microstructures were comparable for coatings from both facilities, and no segmentation cracks were observed. Coating permeability was further reduced by increasing substrate temperatures during deposition or reducing suspension feed rates. On SOFC cathode substrates, coatings made in the production-type facility had higher permeabilities and more segmentation cracks compared with coatings made in the lab-scale facility. Increased cracking in coatings from the production-type facility was likely caused mainly by its lower torch-substrate relative speed.

  10. 15 CFR 712.4 - New Schedule 1 production facility.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE CHEMICAL WEAPONS CONVENTION REGULATIONS ACTIVITIES INVOLVING SCHEDULE 1 CHEMICALS § 712.4 New Schedule 1 production facility. (a) Establishment of a...) of the CWCR, and you intend to begin production of Schedule 1 chemicals at your facility in...

  11. 43 CFR 3164.1 - Onshore Oil and Gas Orders.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    .... 27, 1989, new facilities greater than 200 MCF production; Aug. 23, 1989, existing facility greater than 200 MCF production; Feb. 26, 1990, existing facility less than 200 MCF production 54 FR 8100 None. 6. Hydrogen sulfide operations Jan. 22, 1991 55 FR 48958 None. 7. Disposal of produced water October...

  12. 18 CFR 292.203 - General requirements for qualification.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... certification, pursuant to § 292.207(b)(1), that has been granted. (c) Hydroelectric small power production facilities located at a new dam or diversion. (1) A hydroelectric small power production facility that..., pursuant to § 292.207(b)(1), that has been granted. (c) Hydroelectric small power production facilities...

  13. 9 CFR 307.1 - Facilities for Program employees.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 9 Animals and Animal Products 2 2012-01-01 2012-01-01 false Facilities for Program employees. 307.1 Section 307.1 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE AGENCY ORGANIZATION AND TERMINOLOGY; MANDATORY MEAT AND POULTRY PRODUCTS INSPECTION AND VOLUNTARY INSPECTION AND CERTIFICATION FACILITIES FOR...

  14. 9 CFR 307.1 - Facilities for Program employees.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 9 Animals and Animal Products 2 2011-01-01 2011-01-01 false Facilities for Program employees. 307.1 Section 307.1 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE AGENCY ORGANIZATION AND TERMINOLOGY; MANDATORY MEAT AND POULTRY PRODUCTS INSPECTION AND VOLUNTARY INSPECTION AND CERTIFICATION FACILITIES FOR...

  15. 9 CFR 307.1 - Facilities for Program employees.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 9 Animals and Animal Products 2 2013-01-01 2013-01-01 false Facilities for Program employees. 307.1 Section 307.1 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE AGENCY ORGANIZATION AND TERMINOLOGY; MANDATORY MEAT AND POULTRY PRODUCTS INSPECTION AND VOLUNTARY INSPECTION AND CERTIFICATION FACILITIES FOR...

  16. 15 CFR 712.4 - New Schedule 1 production facility.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE CHEMICAL WEAPONS CONVENTION REGULATIONS ACTIVITIES INVOLVING SCHEDULE 1 CHEMICALS § 712.4 New Schedule 1 production facility. (a) Establishment of a...) of the CWCR, and you intend to begin production of Schedule 1 chemicals at your facility in...

  17. Vector production in an academic environment: a tool to assess production costs.

    PubMed

    Boeke, Aaron; Doumas, Patrick; Reeves, Lilith; McClurg, Kyle; Bischof, Daniela; Sego, Lina; Auberry, Alisha; Tatikonda, Mohan; Cornetta, Kenneth

    2013-02-01

    Generating gene and cell therapy products under good manufacturing practices is a complex process. When determining the cost of these products, researchers must consider the large number of supplies used for manufacturing and the personnel and facility costs to generate vector and maintain a cleanroom facility. To facilitate cost estimates, the Indiana University Vector Production Facility teamed with the Indiana University Kelley School of Business to develop a costing tool that, in turn, provides pricing. The tool is designed in Microsoft Excel and is customizable to meet the needs of other core facilities. It is available from the National Gene Vector Biorepository. The tool allows cost determinations using three different costing methods and was developed in an effort to meet the A21 circular requirements for U.S. core facilities performing work for federally funded projects. The costing tool analysis reveals that the cost of vector production does not have a linear relationship with batch size. For example, increasing the production from 9 to18 liters of a retroviral vector product increases total costs a modest 1.2-fold rather than doubling in total cost. The analysis discussed in this article will help core facilities and investigators plan a cost-effective strategy for gene and cell therapy production.

  18. Vector Production in an Academic Environment: A Tool to Assess Production Costs

    PubMed Central

    Boeke, Aaron; Doumas, Patrick; Reeves, Lilith; McClurg, Kyle; Bischof, Daniela; Sego, Lina; Auberry, Alisha; Tatikonda, Mohan

    2013-01-01

    Abstract Generating gene and cell therapy products under good manufacturing practices is a complex process. When determining the cost of these products, researchers must consider the large number of supplies used for manufacturing and the personnel and facility costs to generate vector and maintain a cleanroom facility. To facilitate cost estimates, the Indiana University Vector Production Facility teamed with the Indiana University Kelley School of Business to develop a costing tool that, in turn, provides pricing. The tool is designed in Microsoft Excel and is customizable to meet the needs of other core facilities. It is available from the National Gene Vector Biorepository. The tool allows cost determinations using three different costing methods and was developed in an effort to meet the A21 circular requirements for U.S. core facilities performing work for federally funded projects. The costing tool analysis reveals that the cost of vector production does not have a linear relationship with batch size. For example, increasing the production from 9 to18 liters of a retroviral vector product increases total costs a modest 1.2-fold rather than doubling in total cost. The analysis discussed in this article will help core facilities and investigators plan a cost-effective strategy for gene and cell therapy production. PMID:23360377

  19. 9 CFR 2.37 - Federal research facilities.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Federal research facilities. 2.37 Section 2.37 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ANIMAL WELFARE REGULATIONS Research Facilities § 2.37 Federal research facilities. Each Federal...

  20. 9 CFR 590.538 - Defrosting facilities.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Defrosting facilities. 590.538 Section 590.538 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE EGG..., and Facility Requirements § 590.538 Defrosting facilities. (a) Approved metal defrosting tanks or vats...

  1. 9 CFR 590.534 - Freezing facilities.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Freezing facilities. 590.534 Section 590.534 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE EGG..., and Facility Requirements § 590.534 Freezing facilities. (a) Freezing rooms, either on or off the...

  2. Estimates of Radioxenon Released from Southern Hemisphere Medical isotope Production Facilities Using Measured Air Concentrations and Atmospheric Transport Modeling

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Eslinger, Paul W.; Friese, Judah I.; Lowrey, Justin D.

    2014-09-01

    Abstract The International Monitoring System (IMS) of the Comprehensive-Nuclear-Test-Ban-Treaty monitors the atmosphere for radioactive xenon leaking from underground nuclear explosions. Emissions from medical isotope production represent a challenging background signal when determining whether measured radioxenon in the atmosphere is associated with a nuclear explosion prohibited by the treaty. The Australian Nuclear Science and Technology Organisation (ANSTO) operates a reactor and medical isotope production facility in Lucas Heights, Australia. This study uses two years of release data from the ANSTO medical isotope production facility and Xe-133 data from three IMS sampling locations to estimate the annual releases of Xe-133 from medicalmore » isotope production facilities in Argentina, South Africa, and Indonesia. Atmospheric dilution factors derived from a global atmospheric transport model were used in an optimization scheme to estimate annual release values by facility. The annual releases of about 6.8×1014 Bq from the ANSTO medical isotope production facility are in good agreement with the sampled concentrations at these three IMS sampling locations. Annual release estimates for the facility in South Africa vary from 1.2×1016 to 2.5×1016 Bq and estimates for the facility in Indonesia vary from 6.1×1013 to 3.6×1014 Bq. Although some releases from the facility in Argentina may reach these IMS sampling locations, the solution to the objective function is insensitive to the magnitude of those releases.« less

  3. 18 CFR 292.209 - Exceptions from requirements for hydroelectric small power production facilities located at a new...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... requirements for hydroelectric small power production facilities located at a new dam or diversion. 292.209... Exceptions from requirements for hydroelectric small power production facilities located at a new dam or... the Federal Power Act, at which non-Federal hydroelectric development is permissible; or (2) An...

  4. 18 CFR 292.209 - Exceptions from requirements for hydroelectric small power production facilities located at a new...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... requirements for hydroelectric small power production facilities located at a new dam or diversion. 292.209... Exceptions from requirements for hydroelectric small power production facilities located at a new dam or... the Federal Power Act, at which non-Federal hydroelectric development is permissible; or (2) An...

  5. 18 CFR 292.209 - Exceptions from requirements for hydroelectric small power production facilities located at a new...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... requirements for hydroelectric small power production facilities located at a new dam or diversion. 292.209... Exceptions from requirements for hydroelectric small power production facilities located at a new dam or... the Federal Power Act, at which non-Federal hydroelectric development is permissible; or (2) An...

  6. 78 FR 36744 - Diamond Sawblades and Parts Thereof From the People's Republic of China: Preliminary Results of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-19

    ... management, production facilities, supplier relationships, and customer base.\\5\\ While no single factor or... significant changes to management, production facilities, supplier relationships, and customers. As a result..., production facilities, and customer/ supplier relationships have not changed as a result of the name change...

  7. 43 CFR 3212.24 - How will the production incentive apply to a new facility?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... (Continued) BUREAU OF LAND MANAGEMENT, DEPARTMENT OF THE INTERIOR MINERALS MANAGEMENT (3000) GEOTHERMAL... Royalty Rate Conversions § 3212.24 How will the production incentive apply to a new facility? (a) If BLM... electricity from the new facility. (b) The amount of the production incentive is established in MMS...

  8. 43 CFR 3212.24 - How will the production incentive apply to a new facility?

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... (Continued) BUREAU OF LAND MANAGEMENT, DEPARTMENT OF THE INTERIOR MINERALS MANAGEMENT (3000) GEOTHERMAL... Royalty Rate Conversions § 3212.24 How will the production incentive apply to a new facility? (a) If BLM... electricity from the new facility. (b) The amount of the production incentive is established in MMS...

  9. 43 CFR 3212.24 - How will the production incentive apply to a new facility?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... (Continued) BUREAU OF LAND MANAGEMENT, DEPARTMENT OF THE INTERIOR MINERALS MANAGEMENT (3000) GEOTHERMAL... Royalty Rate Conversions § 3212.24 How will the production incentive apply to a new facility? (a) If BLM... electricity from the new facility. (b) The amount of the production incentive is established in MMS...

  10. New Ideas on Facilities Management.

    ERIC Educational Resources Information Center

    Grimm, James C.

    1986-01-01

    Examines trends in facilities management relating to products and people. Reviews new trends in products, including processes, techniques, and programs that are being expounded by business and industry. Discusses the "people factors" involved in facilities management. (ABB)

  11. Production and Injection data for NV Binary facilities

    DOE Data Explorer

    Mines, Greg

    2013-12-24

    Excel files are provided with well production and injection data for binary facilities in Nevada. The files contain the data that reported montly to the Nevada Bureau of Mines and Geology (NBMG) by the facility operators. this data has been complied into Excel spreadsheets for each of the facilities given on the NBMG web site.

  12. Capsule review of the DOE research and development and field facilities

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None

    1980-09-01

    A description is given of the roles of DOE's headquarters, field offices, major multiprogram laboratories, Energy Technology and Mining Technology Centers, and other government-owned, contractor-operated facilities, which are located in all regions of the US. Descriptions of DOE facilities are given for multiprogram laboratories (12); program-dedicated facilities (biomedical and environmental facilities-12, fossil energy facilities-7, fusion energy facility-1, nuclear development facilities-3, physical research facilities-4, safeguards facility-1, and solar facilities-2); and Production, Testing, and Fabrication Facilities (nuclear materials production facilities-5, weapon testing and fabrication complex-8). Three appendices list DOE field and project offices; DOE field facilities by state or territory, names, addresses,more » and telephone numbers; DOE R and D field facilities by type, contractor names, and names of directors. (MCW)« less

  13. 77 FR 64999 - Guidance for Industry: Necessity of the Use of Food Product Categories in Food Facility...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-24

    ...] Guidance for Industry: Necessity of the Use of Food Product Categories in Food Facility Registrations and... industry entitled ``Necessity of the Use of Food Product Categories in Food Facility Registrations and... made available a draft guidance entitled ``Guidance for Industry: Necessity of the Use of Food [[Page...

  14. Using mobile distributed pyrolysis facilities to deliver a forest residue resource for bio-fuel production

    NASA Astrophysics Data System (ADS)

    Brown, Duncan

    Distributed mobile conversion facilities using either fast pyrolysis or torrefaction processes can be used to convert forest residues to more energy dense substances (bio-oil, bio-slurry or torrefied wood) that can be transported as feedstock for bio-fuel facilities. All feedstock are suited for gasification, which produces syngas that can be used to synthesise petrol or diesel via Fischer-Tropsch reactions, or produce hydrogen via water gas shift reactions. Alternatively, the bio-oil product of fast pyrolysis may be upgraded to produce petrol and diesel, or can undergo steam reformation to produce hydrogen. Implementing a network of mobile facilities reduces the energy content of forest residues delivered to a bio-fuel facility as mobile facilities use a fraction of the biomass energy content to meet thermal or electrical demands. The total energy delivered by bio-oil, bio-slurry and torrefied wood is 45%, 65% and 87% of the initial forest residue energy content, respectively. However, implementing mobile facilities is economically feasible when large transport distances are required. For an annual harvest of 1.717 million m3 (equivalent to 2000 ODTPD), transport costs are reduced to less than 40% of the total levelised delivered feedstock cost when mobile facilities are implemented; transport costs account for up to 80% of feedstock costs for conventional woodchip delivery. Torrefaction provides the lowest cost pathway of delivering a forest residue resource when using mobile facilities. Cost savings occur against woodchip delivery for annual forest residue harvests above 2.25 million m3 or when transport distances greater than 250 km are required. Important parameters that influence levelised delivered costs of feedstock are transport distances (forest residue spatial density), haul cost factors, thermal and electrical demands of mobile facilities, and initial moisture content of forest residues. Relocating mobile facilities can be optimised for lowest cost delivery as transport distances of raw biomass are reduced. The overall cost of bio-fuel production is determined by the feedstock delivery pathway and also the bio-fuel production process employed. Results show that the minimum cost of petrol and diesel production is 0.86 litre -1 when a bio-oil feedstock is upgraded. This corresponds to a 2750 TPD upgrading facility requiring an annual harvest of 4.30 million m3. The miniμm cost of hydrogen production is 2.92 kg -1, via the gasification of a woodchip feedstock and subsequent water gas shift reactions. This corresponds to a 1100 ODTPD facility and requires an annual harvest of 947,000 m3. The levelised cost of bio-fuel strongly depends on the size of annual harvest required for bio-fuel facilities. There are optimal harvest volumes (bio-fuel facility sizes) for each bio-fuel production route, which yield minimum bio-fuel production costs. These occur as the benefits of economies of scale for larger bio-fuel facilities compete against increasing transport costs for larger harvests. Optimal harvest volumes are larger for bio-fuel production routes that use feedstock sourced from mobile facilities, as mobile facilities reduce total transport requirements.

  15. Comparison of facility-level methane emission rates from natural gas production well pads in the Marcellus, Denver-Julesburg, and Uintah Basins

    NASA Astrophysics Data System (ADS)

    Omara, M.; Li, X.; Sullivan, M.; Subramanian, R.; Robinson, A. L.; Presto, A. A.

    2015-12-01

    The boom in shale natural gas (NG) production, brought about by advances in horizontal drilling and hydraulic fracturing, has yielded both economic benefits and concerns about environmental and climate impacts. In particular, leakages of methane from the NG supply chain could substantially increase the carbon footprint of NG, diminishing its potential role as a transition fuel between carbon intensive fossil fuels and renewable energy systems. Recent research has demonstrated significant variability in measured methane emission rates from NG production facilities within a given shale gas basin. This variability often reflect facility-specific differences in NG production capacity, facility age, utilization of emissions capture and control, and/or the level of facility inspection and maintenance. Across NG production basins, these differences in facility-level methane emission rates are likely amplified, especially if significant variability in NG composition and state emissions regulations are present. In this study, we measured methane emission rates from the NG production sector in the Marcellus Shale Basin (Pennsylvania and West Virginia), currently the largest NG production basin in the U.S., and contrast these results with those of the Denver-Julesburg (Colorado) and Uintah (Utah) shale basins. Facility-level methane emission rates were measured at 106 NG production facilities using the dual tracer flux (nitrous oxide and acetylene), Gaussian dispersion simulations, and the OTM 33A techniques. The distribution of facility-level average methane emission rate for each NG basin will be discussed, with emphasis on how variability in NG composition (i.e., ethane-to-methane ratios) and state emissions regulations impact measured methane leak rates. While the focus of this presentation will be on the comparison of methane leak rates among NG basins, the use of three complimentary top-down methane measurement techniques provides a unique opportunity to explore the effectiveness of each approach, which will also be discussed.

  16. 18 CFR 292.209 - Exceptions from requirements for hydroelectric small power production facilities located at a new...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... requirements for hydroelectric small power production facilities located at a new dam or diversion. 292.209... Exceptions from requirements for hydroelectric small power production facilities located at a new dam or... license or exemption is filed for a project located at a Government dam, as defined in section 3(10) of...

  17. 18 CFR 292.209 - Exceptions from requirements for hydroelectric small power production facilities located at a new...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... requirements for hydroelectric small power production facilities located at a new dam or diversion. 292.209... Exceptions from requirements for hydroelectric small power production facilities located at a new dam or... license or exemption is filed for a project located at a Government dam, as defined in section 3(10) of...

  18. Control of Listeria species food safety at a poultry food production facility.

    PubMed

    Fox, Edward M; Wall, Patrick G; Fanning, Séamus

    2015-10-01

    Surveillance and control of food-borne human pathogens, such as Listeria monocytogenes, is a critical aspect of modern food safety programs at food production facilities. This study evaluated contamination patterns of Listeria species at a poultry food production facility, and evaluated the efficacy of procedures to control the contamination and transfer of the bacteria throughout the plant. The presence of Listeria species was studied along the production chain, including raw ingredients, food-contact, non-food-contact surfaces, and finished product. All isolates were sub-typed by pulsed-field gel electrophoresis (PFGE) to identify possible entry points for Listeria species into the production chain, as well as identifying possible transfer routes through the facility. The efficacy of selected in-house sanitizers against a sub-set of the isolates was evaluated. Of the 77 different PFGE-types identified, 10 were found among two or more of the five categories/areas (ingredients, food preparation, cooking and packing, bulk packing, and product), indicating potential transfer routes at the facility. One of the six sanitizers used was identified as unsuitable for control of Listeria species. Combining PFGE data, together with information on isolate location and timeframe, facilitated identification of a persistent Listeria species contamination that had colonized the facility, along with others that were transient. Copyright © 2015 Elsevier Ltd. All rights reserved.

  19. 75 FR 15655 - Requirements for Control Technology Determinations for Major Sources in Accordance With Clean Air...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-30

    ... and/or copolymer products. Brick and Structural Clay Products...... 327121 Brick and structural clay tile manufacturing facilities. Brick and Structural Clay Products; Clay 327122 Ceramic wall and floor... Structural Clay Products...... 327123 Other structural clay products manufacturing facilities. Clay Ceramics...

  20. 7 CFR 70.110 - Requirements for sanitation, facilities, and operating procedures in official plants.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... PRODUCTS INSPECTION ACT (CONTINUED) VOLUNTARY GRADING OF POULTRY PRODUCTS AND RABBIT PRODUCTS Grading of Poultry Products and Rabbit Products Sanitary Requirements, Facilities, and Operating Procedures § 70.110... in 9 CFR part 381 for poultry, and for rabbits the requirements shall be the applicable provisions...

  1. 7 CFR 70.110 - Requirements for sanitation, facilities, and operating procedures in official plants.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... PRODUCTS INSPECTION ACT (CONTINUED) VOLUNTARY GRADING OF POULTRY PRODUCTS AND RABBIT PRODUCTS Grading of Poultry Products and Rabbit Products Sanitary Requirements, Facilities, and Operating Procedures § 70.110... in 9 CFR part 381 for poultry, and for rabbits the requirements shall be the applicable provisions...

  2. Farm Animal Models of Organic Dust Exposure and Toxicity: Insights and Implications for Respiratory Health

    PubMed Central

    McClendon, Chakia J.; Gerald, Carresse L.; Waterman, Jenora T.

    2016-01-01

    Purpose of review Modern food animal production is a major contributor to the global economy, owing to advanced intensive indoor production facilities aimed at increasing market readiness and profit. Consequences of these advances are accumulation of dusts, gases and microbial products that diminish air quality within production facilities. Chronic inhalation exposure contributes to onset and exacerbation of respiratory symptoms and diseases in animals and workers. This article reviews literature regarding constituents of farm animal production facility dusts; animal responses to production building and organic dust exposure, and the effect of chronic inhalation exposure on pulmonary oxidative stress and inflammation. Recent findings –Porcine models of production facility and organic dust exposures reveal striking similarities to observations of human cells, tissues and clinical data. Oxidative stress plays a key role in mediating respiratory diseases in animals and humans, and enhancement of antioxidant levels through nutritional supplements can improve respiratory health. Summary – Pigs are well adapted to the exposures common to swine production buildings and thus serve as excellent models for facility workers. Insight for understanding mechanisms governing organic dust associated respiratory diseases may come from parallel comparisons between farmers and the animals they raise. PMID:25636160

  3. Coal gasification systems engineering and analysis. Appendix C: Alternate product facility designs

    NASA Technical Reports Server (NTRS)

    1980-01-01

    The study of the production of methane, methanol, gasoline, and hydrogen by an add-on facility to a Koppers-Totzek based MBG plant is presented. Applications to a Texaco facility are inferred by evaluation of delta effects from the K-T cases. The production of methane from an add-on facility to a Lurgi based MBG plant and the co-production of methane and methanol from a Lurgi based system is studied. Studies are included of the production of methane from up to 50 percent of the MBG produced in an integrated K-T based plant and the production of methane from up to 50 percent of the MBG produced from an integrated plant in which module 1 is based on K-T technology and modules 2, 3, and 4 are based on Texaco technology.

  4. 40 CFR 372.3 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    .... (9) Methane reforming furnaces. (10) Pulping liquor recovery furnaces. (11) Combustion devices used... production of acid from halogenated hazardous waste generated by chemical production facilities where the furnace is located on the site of a chemical production facility, the acid product has a halogen acid...

  5. Contamination issues in a continuous ethanol production corn wet milling facility

    USDA-ARS?s Scientific Manuscript database

    Low ethanol yields and poor yeast viability were investigated at a continuous ethanol production corn wet milling facility. Using starch slurries and recycle streams from a commercial ethanol facility, laboratory hydrolysates were prepared by reproducing starch liquefaction and saccharification ste...

  6. 40 CFR 80.1449 - What are the Production Outlook Report requirements?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... planned or underway, information on all the following, as available: (i) Strategic planning. (ii) Planning... and production processes to be used at each production facility. (iv) Changes to the facility that...

  7. 14 CFR 21.165 - Responsibility of holder.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... supplier and subsequently found not to conform to the applicable design data. (d) Manufacturing process... facilities. (a) An applicant may obtain a production certificate for manufacturing facilities located outside... before making any changes to the location of any of its manufacturing facilities. (c) The production...

  8. A National Study of Efficiency for Dialysis Centers: An Examination of Market Competition and Facility Characteristics for Production of Multiple Dialysis Outputs

    PubMed Central

    Ozgen, Hacer; A. Ozcan, Yasar

    2002-01-01

    Objective To examine market competition and facility characteristics that can be related to technical efficiency in the production of multiple dialysis outputs from the perspective of the industrial organization model. Study Setting Freestanding dialysis facilities that operated in 1997 submitted cost report forms to the Health Care Financing Administration (HCFA), and offered all three outputs—outpatient dialysis, dialysis training, and home program dialysis. Data Sources The Independent Renal Facility Cost Report Data file (IRFCRD) from HCFA was utilized to obtain information on output and input variables and market and facility features for 791 multiple-output facilities. Information regarding population characteristics was obtained from the Area Resources File. Study Design Cross-sectional data for the year 1997 were utilized to obtain facility-specific technical efficiency scores estimated through Data Envelopment Analysis (DEA). A binary variable of efficiency status was then regressed against its market and facility characteristics and control factors in a multivariate logistic regression analysis. Principal Findings The majority of the facilities in the sample are functioning technically inefficiently. Neither the intensity of market competition nor a policy of dialyzer reuse has a significant effect on the facilities' efficiency. Technical efficiency is significantly associated, however, with type of ownership, with the interaction between the market concentration of for-profits and ownership type, and with affiliations with chains of different sizes. Nonprofit and government-owned facilities are more likely than their for-profit counterparts to become inefficient producers of renal dialysis outputs. On the other hand, that relationship between ownership form and efficiency is reversed as the market concentration of for-profits in a given market increases. Facilities that are members of large chains are more likely to be technically inefficient. Conclusions Facilities do not appear to benefit from joint production of a variety of dialysis outputs, which may explain the ongoing tendency toward single-output production. Ownership form does make a positive difference in production efficiency, but only in local markets where competition exists between nonprofit and for-profit facilities. The increasing inefficiency associated with membership in large chains suggests that the growing consolidation in the dialysis industry may not, in fact, be the strategy for attaining more technical efficiency in the production of multiple dialysis outputs. PMID:12132602

  9. A national study of efficiency for dialysis centers: an examination of market competition and facility characteristics for production of multiple dialysis outputs.

    PubMed

    Ozgen, Hacer; Ozcan, Yasar A

    2002-06-01

    To examine market competition and facility characteristics that can be related to technical efficiency in the production of multiple dialysis outputs from the perspective of the industrial organization model. Freestanding dialysis facilities that operated in 1997 submitted cost report fonns to the Health Care Financing Administration (HCFA), and offered all three outputs--outpatient dialysis, dialysis training, and home program dialysis. The Independent Renal Facility Cost Report Data file (IRFCRD) from HCFA was utilized to obtain information on output and input variables and market and facility features for 791 multiple-output facilities. Information regarding population characteristics was obtained from the Area Resources File. Cross-sectional data for the year 1997 were utilized to obtain facility-specific technical efficiency scores estimated through Data Envelopment Analysis (DEA). A binary variable of efficiency status was then regressed against its market and facility characteristics and control factors in a multivariate logistic regression analysis. The majority of the facilities in the sample are functioning technically inefficiently. Neither the intensity of market competition nor a policy of dialyzer reuse has a significant effect on the facilities' efficiency. Technical efficiency is significantly associated, however, with type of ownership, with the interaction between the market concentration of for-profits and ownership type, and with affiliations with chains of different sizes. Nonprofit and government-owned Facilities are more likely than their for-profit counterparts to become inefficient producers of renal dialysis outputs. On the other hand, that relationship between ownership form and efficiency is reversed as the market concentration of for-profits in a given market increases. Facilities that are members of large chains are more likely to be technically inefficient. Facilities do not appear to benefit from joint production of a variety of dialysis outputs, which may explain the ongoing tendency toward single-output production. Ownership form does make a positive difference in production efficiency, but only in local markets where competition exists between nonprofit and for-profit facilities. The increasing inefficiency associated with membership in large chains suggests that the growing consolidation in the dialysis industry may not, in fact, be the strategy for attaining more technical efficiency in the production of multiple dialysis outputs.

  10. 9 CFR 590.570 - Pasteurization of liquid eggs.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Pasteurization of liquid eggs. 590.570... EGG PRODUCTS INSPECTION INSPECTION OF EGGS AND EGG PRODUCTS (EGG PRODUCTS INSPECTION ACT) Sanitary, Processing, and Facility Requirements § 590.570 Pasteurization of liquid eggs. (a) Pasteurization facilities...

  11. 9 CFR 590.570 - Pasteurization of liquid eggs.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 9 Animals and Animal Products 2 2011-01-01 2011-01-01 false Pasteurization of liquid eggs. 590.570... EGG PRODUCTS INSPECTION INSPECTION OF EGGS AND EGG PRODUCTS (EGG PRODUCTS INSPECTION ACT) Sanitary, Processing, and Facility Requirements § 590.570 Pasteurization of liquid eggs. (a) Pasteurization facilities...

  12. Measuring Clinical Productivity.

    PubMed

    Hudson, Mark E; Lebovitz, Evan E

    2018-06-01

    Productivity measurements have been used to evaluate and compare physicians and physician practices. Anesthesiology is unique in that factors outside anesthesiologist control impact opportunity for revenue generation and make comparisons between providers and facilities challenging. This article uses data from the multicenter University of Pittsburgh Physicians Department of Anesthesiology to demonstrate factors influencing productivity opportunity by surgical facility, between department divisions and subspecialties within multispecialty divisions, and by individuals within divisions. The complexities of benchmarking anesthesiology productivity are demonstrated, and the potential value of creating a productivity profile for facilities and groups is illustrated. Copyright © 2018 Elsevier Inc. All rights reserved.

  13. 9 CFR 2.102 - Holding facility.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... animals remain under the total control and responsibility of the research facility or intermediate handler... 9 Animals and Animal Products 1 2011-01-01 2011-01-01 false Holding facility. 2.102 Section 2.102 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ANIMAL...

  14. 9 CFR 2.102 - Holding facility.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... animals remain under the total control and responsibility of the research facility or intermediate handler... 9 Animals and Animal Products 1 2012-01-01 2012-01-01 false Holding facility. 2.102 Section 2.102 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ANIMAL...

  15. Analysis of the photoneutron activation effects generated by 9 MeV X-ray in a container cargo inspection facility.

    PubMed

    Cho, Young Ho; Kang, Bo Sun

    2010-06-01

    The X-ray container cargo inspection facility is extensively implemented with the key objective to counter international terrorism and illicit smuggling of the contraband items via the ports. However, activation products are generated from photoneutron capture reactions in the high-energy X-ray container cargo inspection facility. The activation products release inherent delayed radiations which occupational workers are exposed to. In this study, the activation products are estimated using Monte Carlo method and radiation safety of the facility in terms of occupational dose is reviewed.

  16. 78 FR 72897 - Draft Guidance for Industry on Interim Product Reporting for Human Drug Compounding Outsourcing...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-04

    ...] Draft Guidance for Industry on Interim Product Reporting for Human Drug Compounding Outsourcing... Compounding Outsourcing Facilities Under Section 503B of the Federal Food, Drug, and Cosmetic Act.'' The draft... human drug compounders that choose to register as outsourcing facilities (outsourcing facilities). DATES...

  17. 9 CFR 3.91 - Terminal facilities.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 9 Animals and Animal Products 1 2014-01-01 2014-01-01 false Terminal facilities. 3.91 Section 3.91 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ANIMAL... animal holding area of a terminal facility must provide the following: (1) Shelter from sunlight and...

  18. 9 CFR 3.91 - Terminal facilities.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 9 Animals and Animal Products 1 2012-01-01 2012-01-01 false Terminal facilities. 3.91 Section 3.91 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ANIMAL... animal holding area of a terminal facility must provide the following: (1) Shelter from sunlight and...

  19. 9 CFR 3.91 - Terminal facilities.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 9 Animals and Animal Products 1 2013-01-01 2013-01-01 false Terminal facilities. 3.91 Section 3.91 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ANIMAL... animal holding area of a terminal facility must provide the following: (1) Shelter from sunlight and...

  20. 9 CFR 2.102 - Holding facility.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Holding facility. 2.102 Section 2.102 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ANIMAL WELFARE REGULATIONS Compliance With Standards and Holding Period § 2.102 Holding facility. (a) If any...

  1. 18 CFR 292.204 - Criteria for qualifying small power production facilities.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... primary energy source of the facility must be biomass, waste, renewable resources, geothermal resources... FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY REGULATIONS UNDER THE PUBLIC UTILITY REGULATORY... production facilities that use the same energy resource, are owned by the same person(s) or its affiliates...

  2. 30 CFR 210.204 - How do I submit facility data?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 210.204 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR MINERALS REVENUE MANAGEMENT FORMS AND REPORTS Production and Royalty Reports-Solid Minerals § 210.204 How do I submit facility...) Output quality or product grades. (5) Your submitted facility data may be internally generated documents...

  3. 9 CFR 11.6 - Inspection space and facility requirements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Inspection space and facility requirements. 11.6 Section 11.6 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ANIMAL WELFARE HORSE PROTECTION REGULATIONS § 11.6 Inspection space and facility...

  4. 27 CFR 19.86 - Furnishing facilities and assistance.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Furnishing facilities and assistance. 19.86 Section 19.86 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE... Provisions Entry and Examination of Premises § 19.86 Furnishing facilities and assistance. On the demand of...

  5. 18 CFR 292.309 - Termination of obligation to purchase from qualifying facilities.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... POLICIES ACT OF 1978 WITH REGARD TO SMALL POWER PRODUCTION AND COGENERATION Arrangements Between Electric Utilities and Qualifying Cogeneration and Small Power Production Facilities Under Section 210 of the Public... into a new contract or obligation to purchase electric energy from a qualifying cogeneration facility...

  6. 18 CFR 292.309 - Termination of obligation to purchase from qualifying facilities.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... POLICIES ACT OF 1978 WITH REGARD TO SMALL POWER PRODUCTION AND COGENERATION Arrangements Between Electric Utilities and Qualifying Cogeneration and Small Power Production Facilities Under Section 210 of the Public... into a new contract or obligation to purchase electric energy from a qualifying cogeneration facility...

  7. 18 CFR 292.309 - Termination of obligation to purchase from qualifying facilities.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... POLICIES ACT OF 1978 WITH REGARD TO SMALL POWER PRODUCTION AND COGENERATION Arrangements Between Electric Utilities and Qualifying Cogeneration and Small Power Production Facilities Under Section 210 of the Public... into a new contract or obligation to purchase electric energy from a qualifying cogeneration facility...

  8. 18 CFR 292.309 - Termination of obligation to purchase from qualifying facilities.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... POLICIES ACT OF 1978 WITH REGARD TO SMALL POWER PRODUCTION AND COGENERATION Arrangements Between Electric Utilities and Qualifying Cogeneration and Small Power Production Facilities Under Section 210 of the Public... into a new contract or obligation to purchase electric energy from a qualifying cogeneration facility...

  9. 18 CFR 292.309 - Termination of obligation to purchase from qualifying facilities.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... POLICIES ACT OF 1978 WITH REGARD TO SMALL POWER PRODUCTION AND COGENERATION Arrangements Between Electric Utilities and Qualifying Cogeneration and Small Power Production Facilities Under Section 210 of the Public... into a new contract or obligation to purchase electric energy from a qualifying cogeneration facility...

  10. 9 CFR 590.520 - Breaking room facilities.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Breaking room facilities. 590.520 Section 590.520 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE..., clean towels or other facilities for drying hands, odorless soap, and containers for used towels. Hand...

  11. 9 CFR 108.9 - Dressing rooms and other facilities.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Dressing rooms and other facilities. 108.9 Section 108.9 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT... REQUIREMENTS FOR LICENSED ESTABLISHMENTS § 108.9 Dressing rooms and other facilities. Each licensed...

  12. 7 CFR 4288.25 - Succession and control of facilities and production.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 15 2012-01-01 2012-01-01 false Succession and control of facilities and production... Repowering Assistance Payments to Eligible Biorefineries § 4288.25 Succession and control of facilities and... that, the party is eligible, and permitting such succession would serve the purposes of the program. If...

  13. 7 CFR 4288.25 - Succession and control of facilities and production.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 15 2013-01-01 2013-01-01 false Succession and control of facilities and production... Repowering Assistance Payments to Eligible Biorefineries § 4288.25 Succession and control of facilities and... that, the party is eligible, and permitting such succession would serve the purposes of the program. If...

  14. 7 CFR 4288.25 - Succession and control of facilities and production.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 15 2014-01-01 2014-01-01 false Succession and control of facilities and production... Repowering Assistance Payments to Eligible Biorefineries § 4288.25 Succession and control of facilities and... that, the party is eligible, and permitting such succession would serve the purposes of the program. If...

  15. 15 CFR 712.5 - Annual declaration requirements for facilities engaged in the production of Schedule 1 chemicals...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE CHEMICAL WEAPONS CONVENTION REGULATIONS ACTIVITIES INVOLVING SCHEDULE 1 CHEMICALS § 712.5 Annual declaration requirements for facilities engaged in... facilities engaged in the production of Schedule 1 chemicals for purposes not prohibited by the CWC. 712.5...

  16. 9 CFR 390.4 - Facilities for inspection and copying.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 9 Animals and Animal Products 2 2012-01-01 2012-01-01 false Facilities for inspection and copying. 390.4 Section 390.4 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE FOOD SAFETY AND INSPECTION SERVICE ADMINISTRATIVE PROVISIONS FREEDOM OF INFORMATION AND PUBLIC INFORMATION § 390.4 Facilities for...

  17. 9 CFR 390.4 - Facilities for inspection and copying.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 9 Animals and Animal Products 2 2013-01-01 2013-01-01 false Facilities for inspection and copying. 390.4 Section 390.4 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE FOOD SAFETY AND INSPECTION SERVICE ADMINISTRATIVE PROVISIONS FREEDOM OF INFORMATION AND PUBLIC INFORMATION § 390.4 Facilities for...

  18. 9 CFR 390.4 - Facilities for inspection and copying.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 9 Animals and Animal Products 2 2011-01-01 2011-01-01 false Facilities for inspection and copying. 390.4 Section 390.4 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE FOOD SAFETY AND INSPECTION SERVICE ADMINISTRATIVE PROVISIONS FREEDOM OF INFORMATION AND PUBLIC INFORMATION § 390.4 Facilities for...

  19. 9 CFR 390.4 - Facilities for inspection and copying.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 9 Animals and Animal Products 2 2014-01-01 2014-01-01 false Facilities for inspection and copying. 390.4 Section 390.4 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE FOOD SAFETY AND INSPECTION SERVICE ADMINISTRATIVE PROVISIONS FREEDOM OF INFORMATION AND PUBLIC INFORMATION § 390.4 Facilities for...

  20. Overview of Particle Production Facilities Available in the Czech Republic

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kugler, Andrej

    2007-11-26

    A brief overview of particle production facilities available in Czech Republic is given. In particular are described the facilities at the Nuclear Physics Institute in Rez near Prague, namely: an isochronous cyclotron, an electrostatic accelerator tandetron and a microtron. An outline of the main research projects carried out is included.

  1. Alternative Fuels Data Center

    Science.gov Websites

    and Vehicle Production Property Tax Incentive Alternative fuel production facilities, including biodiesel, biomass, biogas, and ethanol production facilities, may qualify for a reduced property tax rate -in electric vehicles or hybrid electric vehicles, also qualify. In addition, temporary property tax

  2. Hazardous Waste Cleanup: GE Residential Products Incorporated in Palmer Ward, Puerto Rico

    EPA Pesticide Factsheets

    The GE Residential Products, Inc., former Caribe General Electric Products, Inc. (Caribe GE) is an electro-plating facility, located in Palmer Ward, Municipality of Rio Grande, Commonwealth of Puerto Rico. The facility is located on both sides of State

  3. 77 FR 48992 - Tobacco Product Manufacturing Facility Visits

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-15

    ... manufacturing operations--from the receipt of raw materials to the distribution of finished products, and Learn... Manufacturing facilities for materials used for further processing in finished tobacco products (including, but..., parts, accessories, and Manufacturers of materials used for further processing in finished tobacco...

  4. Demonstration of persistent contamination of a cooked egg product production facility with Salmonella enterica serovar Tennessee and characterization of the persistent strain.

    PubMed

    Jakočiūnė, D; Bisgaard, M; Pedersen, K; Olsen, J E

    2014-08-01

    The aim of this study was to investigate whether continuous contamination of light pasteurized egg products with Salmonella enterica serovar Tennessee (S. Tennessee) at a large European producer of industrial egg products was caused by persistent contamination of the production facility and to characterize the persistent strains. Seventy-three S. Tennessee isolates collected from products over a 3-year period with intermittent contamination, and 15 control strains were compared by pulsed field gel electrophoresis (PFGE) using two enzymes. Forty-five case isolates distributed throughout the full period were shown to belong to one profile type. Isolates representing different PFGE profiles were all assigned to ST 319 by multilocus sequence typing (MLST). The case isolates did not show a higher ability to form biofilm on a plastic surface than noncase isolates. Characteristically, members of the persistent clone were weak producers of H2 S in laboratory medium. S. Tennessee isolated from the case was able to grow better in pasteurized egg product compared with other serovars investigated. It was concluded that the contamination was caused by a persistent strain in the production facility and that this strain apparently had adapted to grow in the relevant egg product. S. Tennessee has previously been associated with persistence in hatching facilities. This is the first report of persistent contamination of an egg production facility with this serovar. © 2014 The Society for Applied Microbiology.

  5. Compendium of Low-Cost Pacific Salmon and Steelhead Trout Production Facilities and Practices in the Pacific Northwest.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Senn, Harry G.

    1984-09-01

    The purpose was to research low capital cost salmon and steelhead trout production facilities and identify those that conform with management goals for the Columbia Basin. The species considered were chinook salmon (Oncorhynchus tshawytscha), coho salmon (O. kisutch), sockeye salmon (O. nerka), and steelhead trout (Salmo gairdneri). This report provides a comprehensive listing of the facilities, techniques, and equipment used in artificial production in the Pacific Northwest. (ACR)

  6. Strategy to increase Barangan Banana production in Kabupaten Deli Serdang

    NASA Astrophysics Data System (ADS)

    Adhany, I.; Chalil, D.; Ginting, R.

    2018-02-01

    This study was conducted to analyze internal and external factors in increasing Barangan Banana production in Kabupaten Deli Serdang. Samples were determined by snowball sampling technique and purposive sampling method. Using SWOT analysis method, this study found that there were 6 internal strategic factors and 9 external strategic factors. Among that strategic factors, support for production facilities appears as the most important internal strategic factor, while the demand for Barangan Banana. as the most important external strategic factor. Based on the importance and existing condition of these strategic factors, using support for production facilities and realization of supporting facilities with farming experience are the strategies covering strength-opportunity (SO), organizing mentoring to meet the demand for Barangan Banana are the strategies covering weakness-opportunity (WO), making use of funding support and subsidies to widen the land, using tissue culture seeds and facilities and infrastructures are the strategies covering strength-threat (ST), increas the funding support to widen the land, the use of tissue culture seeds and facilities and infrastructures are the strategies covering weakness-threat (WT) are discussed and proposed to increase Barangan Banana productivity in Kabupaten Deli Serdang.

  7. Synthetic Fiber Production Facilities: New Source Performance Standards (NSPS)

    EPA Pesticide Factsheets

    These standards limits emissions of volatile organic compounds (VOC) from new and reconstructed synthetic fiber production facilities that use solvent-spinning processes. Includes rule history and summary.

  8. PROCESS AND EQUIPMENT CHANGES FOR CLEANER PRODUCTION IN FEDERAL FACILITIES

    EPA Science Inventory

    The paper discusses process and equipment changes for cleaner production in federal facilities. During the 1990s, DoD and EPA conducted joint research and development, aimed at reducing the discharge of hazardous and toxic pollutants from military production and maintenance faci...

  9. 9 CFR 93.210 - Poultry quarantine facilities.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Poultry quarantine facilities. 93.210... AGRICULTURE EXPORTATION AND IMPORTATION OF ANIMALS (INCLUDING POULTRY) AND ANIMAL PRODUCTS IMPORTATION OF CERTAIN ANIMALS, BIRDS, FISH, AND POULTRY, AND CERTAIN ANIMAL, BIRD, AND POULTRY PRODUCTS; REQUIREMENTS...

  10. Real-time Stack Monitoring at the BaTek Medical Isotope Production Facility

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    McIntyre, Justin I.; Agusbudiman, A.; Cameron, Ian M.

    2016-04-01

    Radioxenon emissions from radiopharmaceutical production are a major source of background concentrations affecting the radioxenon detection systems of the International Monitoring System (IMS). Collection of real-time emissions data from production facilities makes it possible to screen out some medical isotope signatures from the IMS radioxenon data sets. This paper describes an effort to obtain and analyze real-time stack emissions data with the design, construction and installation of a small stack monitoring system developed by a joint CTBTO-IDC, BATAN, and PNNL team at the BaTek medical isotope production facility near Jakarta, Indonesia.

  11. 40 CFR Appendix C to Part 122 - Criteria for Determining a Concentrated Aquatic Animal Production Facility (§ 122.24)

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS EPA ADMINISTERED PERMIT PROGRAMS: THE NATIONAL... Concentrated Aquatic Animal Production Facility (§ 122.24) A hatchery, fish farm, or other facility is a... aquatic animals in either of the following categories: (a) Cold water fish species or other cold water...

  12. 40 CFR Appendix C to Part 122 - Criteria for Determining a Concentrated Aquatic Animal Production Facility (§ 122.24)

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS EPA ADMINISTERED PERMIT PROGRAMS: THE NATIONAL... Concentrated Aquatic Animal Production Facility (§ 122.24) A hatchery, fish farm, or other facility is a... aquatic animals in either of the following categories: (a) Cold water fish species or other cold water...

  13. 9 CFR 354.210 - Minimum standards for sanitation, facilities, and operating procedures in official plants.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 9 Animals and Animal Products 2 2012-01-01 2012-01-01 false Minimum standards for sanitation, facilities, and operating procedures in official plants. 354.210 Section 354.210 Animals and Animal Products... sanitation, facilities, and operating procedures in official plants. The provisions of §§ 354.210 to 354.247...

  14. 9 CFR 354.210 - Minimum standards for sanitation, facilities, and operating procedures in official plants.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 9 Animals and Animal Products 2 2011-01-01 2011-01-01 false Minimum standards for sanitation, facilities, and operating procedures in official plants. 354.210 Section 354.210 Animals and Animal Products... sanitation, facilities, and operating procedures in official plants. The provisions of §§ 354.210 to 354.247...

  15. 9 CFR 354.210 - Minimum standards for sanitation, facilities, and operating procedures in official plants.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 9 Animals and Animal Products 2 2014-01-01 2014-01-01 false Minimum standards for sanitation, facilities, and operating procedures in official plants. 354.210 Section 354.210 Animals and Animal Products... sanitation, facilities, and operating procedures in official plants. The provisions of §§ 354.210 to 354.247...

  16. 9 CFR 354.210 - Minimum standards for sanitation, facilities, and operating procedures in official plants.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Minimum standards for sanitation, facilities, and operating procedures in official plants. 354.210 Section 354.210 Animals and Animal Products... sanitation, facilities, and operating procedures in official plants. The provisions of §§ 354.210 to 354.247...

  17. 9 CFR 354.210 - Minimum standards for sanitation, facilities, and operating procedures in official plants.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 9 Animals and Animal Products 2 2013-01-01 2013-01-01 false Minimum standards for sanitation, facilities, and operating procedures in official plants. 354.210 Section 354.210 Animals and Animal Products... sanitation, facilities, and operating procedures in official plants. The provisions of §§ 354.210 to 354.247...

  18. 9 CFR 117.2 - Animal facilities.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 9 Animals and Animal Products 1 2014-01-01 2014-01-01 false Animal facilities. 117.2 Section 117.2 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE VIRUSES, SERUMS, TOXINS, AND ANALOGOUS PRODUCTS; ORGANISMS AND VECTORS ANIMALS AT LICENSED ESTABLISHMENTS § 117.2...

  19. 9 CFR 117.2 - Animal facilities.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 9 Animals and Animal Products 1 2012-01-01 2012-01-01 false Animal facilities. 117.2 Section 117.2 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE VIRUSES, SERUMS, TOXINS, AND ANALOGOUS PRODUCTS; ORGANISMS AND VECTORS ANIMALS AT LICENSED ESTABLISHMENTS § 117.2...

  20. 9 CFR 117.2 - Animal facilities.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Animal facilities. 117.2 Section 117.2 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE VIRUSES, SERUMS, TOXINS, AND ANALOGOUS PRODUCTS; ORGANISMS AND VECTORS ANIMALS AT LICENSED ESTABLISHMENTS § 117.2...

  1. 9 CFR 117.2 - Animal facilities.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 9 Animals and Animal Products 1 2011-01-01 2011-01-01 false Animal facilities. 117.2 Section 117.2 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE VIRUSES, SERUMS, TOXINS, AND ANALOGOUS PRODUCTS; ORGANISMS AND VECTORS ANIMALS AT LICENSED ESTABLISHMENTS § 117.2...

  2. 9 CFR 117.2 - Animal facilities.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 9 Animals and Animal Products 1 2013-01-01 2013-01-01 false Animal facilities. 117.2 Section 117.2 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE VIRUSES, SERUMS, TOXINS, AND ANALOGOUS PRODUCTS; ORGANISMS AND VECTORS ANIMALS AT LICENSED ESTABLISHMENTS § 117.2...

  3. 40 CFR 63.9782 - Am I subject to this subpart?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...) National Emission Standards for Hazardous Air Pollutants for Refractory Products Manufacturing What This... operate a refractory products manufacturing facility that is, is located at, or is part of, a major source... this section. (a) A refractory products manufacturing facility is a plant site that manufactures...

  4. Sapphire Energy - Integrated Algal Biorefinery

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    White, Rebecca L.; Tyler, Mike

    2015-07-22

    Sapphire Energy, Inc. (SEI) is a leader in large-scale photosynthetic algal biomass production, with a strongly cohesive research, development, and operations program. SEI takes a multidiscipline approach to integrate lab-based strain selection, cultivation and harvest and production scale, and extraction for the production of Green Crude oil, a drop in replacement for traditional crude oil.. SEI’s technical accomplishments since 2007 have produced a multifunctional platform that can address needs for fuel, feed, and other higher value products. Figure 1 outlines SEI’s commercialization process, including Green Crude production and refinement to drop in fuel replacements. The large scale algal biomass productionmore » facility, the SEI Integrated Algal Biorefinery (IABR), was built in Luna County near Columbus, New Mexico (see fig 2). The extraction unit was located at the existing SEI facility in Las Cruces, New Mexico, approximately 95 miles from the IABR. The IABR facility was constructed on time and on budget, and the extraction unit expansion to accommodate the biomass output from the IABR was completed in October 2012. The IABR facility uses open pond cultivation with a proprietary harvesting method to produce algal biomass; this biomass is then shipped to the extraction facility for conversion to Green Crude. The operation of the IABR and the extraction facilities has demonstrated the critical integration of traditional agricultural techniques with algae cultivation knowledge for algal biomass production, and the successful conversion of the biomass to Green Crude. All primary unit operations are de-risked, and at a scale suitable for process demonstration. The results are stable, reliable, and long-term cultivation of strains for year round algal biomass production. From June 2012 to November 2014, the IABR and extraction facilities produced 524 metric tons (MT) of biomass (on a dry weight basis), and 2,587 gallons of Green Crude. Additionally, the IABR demonstrated significant year over year yield improvements (2013 to 2014), and reduction in the cost of biomass production. Therefore, the IABR fulfills a number of critical functions in SEI’s integrated development pipeline. These functions are critical in general for the commercialization of algal biomass production and production of biofuels from algal biomass.« less

  5. 9 CFR 3.51 - Facilities, indoor.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 9 Animals and Animal Products 1 2011-01-01 2011-01-01 false Facilities, indoor. 3.51 Section 3.51... Facilities and Operating Standards § 3.51 Facilities, indoor. (a) Heating. Indoor housing facilities for rabbits need not be heated. (b) Ventilation. Indoor housing facilities for rabbits shall be adequately...

  6. 40 CFR 60.560 - Applicability and designation of affected facilities.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... section in a polypropylene or polyethylene production process is a potential affected facility for both... constructed, modified, or reconstructed and, in some instances, on the type of production process. (i) The... reconstructed after January 10, 1989, regardless of the type of production process being used, is January 10...

  7. 40 CFR 60.560 - Applicability and designation of affected facilities.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... section in a polypropylene or polyethylene production process is a potential affected facility for both... constructed, modified, or reconstructed and, in some instances, on the type of production process. (i) The... reconstructed after January 10, 1989, regardless of the type of production process being used, is January 10...

  8. 42 CFR 493.1103 - Standard: Requirements for transfusion services.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... distribution. (1) If a facility stores or maintains blood or blood products for transfusion outside of a... necessary, promptly identify, investigate, and report blood and blood product transfusion reactions to the... availability of blood and blood products. (b) Provision of testing. The facility must provide prompt ABO...

  9. 42 CFR 493.1103 - Standard: Requirements for transfusion services.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... distribution. (1) If a facility stores or maintains blood or blood products for transfusion outside of a... necessary, promptly identify, investigate, and report blood and blood product transfusion reactions to the... availability of blood and blood products. (b) Provision of testing. The facility must provide prompt ABO...

  10. 42 CFR 493.1103 - Standard: Requirements for transfusion services.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... distribution. (1) If a facility stores or maintains blood or blood products for transfusion outside of a... necessary, promptly identify, investigate, and report blood and blood product transfusion reactions to the... availability of blood and blood products. (b) Provision of testing. The facility must provide prompt ABO...

  11. 18 CFR 292.204 - Criteria for qualifying small power production facilities.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 18 Conservation of Power and Water Resources 1 2014-04-01 2014-04-01 false Criteria for qualifying small power production facilities. 292.204 Section 292.204 Conservation of Power and Water Resources... OF 1978 WITH REGARD TO SMALL POWER PRODUCTION AND COGENERATION Qualifying Cogeneration and Small...

  12. 18 CFR 292.204 - Criteria for qualifying small power production facilities.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 18 Conservation of Power and Water Resources 1 2012-04-01 2012-04-01 false Criteria for qualifying small power production facilities. 292.204 Section 292.204 Conservation of Power and Water Resources... OF 1978 WITH REGARD TO SMALL POWER PRODUCTION AND COGENERATION Qualifying Cogeneration and Small...

  13. 18 CFR 292.204 - Criteria for qualifying small power production facilities.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 18 Conservation of Power and Water Resources 1 2013-04-01 2013-04-01 false Criteria for qualifying small power production facilities. 292.204 Section 292.204 Conservation of Power and Water Resources... OF 1978 WITH REGARD TO SMALL POWER PRODUCTION AND COGENERATION Qualifying Cogeneration and Small...

  14. 40 CFR 63.2231 - Does this subpart apply to me?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Standards for Hazardous Air Pollutants: Plywood and Composite Wood Products What This Subpart Covers § 63... manufacturing facility is a facility that manufactures plywood and/or composite wood products by bonding wood... and pressure, to form a structural panel or engineered wood product. Plywood and composite wood...

  15. Product Searching with Shopping Bots.

    ERIC Educational Resources Information Center

    Rowley, Jennifer

    2000-01-01

    Using trial searches for three best-selling books, this study examined the search facilities offered by shopping bots, which support consumers with the product search and identification stage in e-shopping. Findings indicate that effectiveness of bots not only depends upon search facilities but also upon product coverage, and other added value…

  16. EOS MLS Science Data Processing System: A Description of Architecture and Capabilities

    NASA Technical Reports Server (NTRS)

    Cuddy, David T.; Echeverri, Mark D.; Wagner, Paul A.; Hanzel, Audrey T.; Fuller, Ryan A.

    2006-01-01

    This paper describes the architecture and capabilities of the Science Data Processing System (SDPS) for the EOS MLS. The SDPS consists of two major components--the Science Computing Facility and the Science Investigator-led Processing System. The Science Computing Facility provides the facilities for the EOS MLS Science Team to perform the functions of scientific algorithm development, processing software development, quality control of data products, and scientific analyses. The Science Investigator-led Processing System processes and reprocesses the science data for the entire mission and delivers the data products to the Science Computing Facility and to the Goddard Space Flight Center Earth Science Distributed Active Archive Center, which archives and distributes the standard science products.

  17. Appendix E - Sample Production Facility Plan

    EPA Pesticide Factsheets

    This sample Spill Prevention, Control and Countermeasure (SPCC) Plan in Appendix E is intended to provide examples and illustrations of how a production facility could address a variety of scenarios in its SPCC Plan.

  18. Initial utilization of the CVIRB video production facility

    NASA Technical Reports Server (NTRS)

    Parrish, Russell V.; Busquets, Anthony M.; Hogge, Thomas W.

    1987-01-01

    Video disk technology is one of the central themes of a technology demonstrator workstation being assembled as a man/machine interface for the Space Station Data Management Test Bed at Johnson Space Center. Langley Research Center personnel involved in the conception and implementation of this workstation have assembled a video production facility to allow production of video disk material for this propose. This paper documents the initial familiarization efforts in the field of video production for those personnel and that facility. Although the entire video disk production cycle was not operational for this initial effort, the production of a simulated disk on video tape did acquaint the personnel with the processes involved and with the operation of the hardware. Invaluable experience in storyboarding, script writing, audio and video recording, and audio and video editing was gained in the production process.

  19. An Integrated Assessment of Location-Dependent Scaling for Microalgae Biofuel Production Facilities

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Coleman, Andre M.; Abodeely, Jared; Skaggs, Richard

    Successful development of a large-scale microalgae-based biofuels industry requires comprehensive analysis and understanding of the feedstock supply chain—from facility siting/design through processing/upgrading of the feedstock to a fuel product. The evolution from pilot-scale production facilities to energy-scale operations presents many multi-disciplinary challenges, including a sustainable supply of water and nutrients, operational and infrastructure logistics, and economic competitiveness with petroleum-based fuels. These challenges are addressed in part by applying the Integrated Assessment Framework (IAF)—an integrated multi-scale modeling, analysis, and data management suite—to address key issues in developing and operating an open-pond facility by analyzing how variability and uncertainty in space andmore » time affect algal feedstock production rates, and determining the site-specific “optimum” facility scale to minimize capital and operational expenses. This approach explicitly and systematically assesses the interdependence of biofuel production potential, associated resource requirements, and production system design trade-offs. The IAF was applied to a set of sites previously identified as having the potential to cumulatively produce 5 billion-gallons/year in the southeastern U.S. and results indicate costs can be reduced by selecting the most effective processing technology pathway and scaling downstream processing capabilities to fit site-specific growing conditions, available resources, and algal strains.« less

  20. 15 CFR 712.5 - Annual declaration requirements for facilities engaged in the production of Schedule 1 chemicals...

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...)(2) of this section if you produced at your facility in excess of 100 grams aggregate of Schedule 1... you will produce at your facility more than 100 grams aggregate of Schedule 1 chemicals in the next... result in production of more than 100 grams aggregate of Schedule 1 chemicals. (b) Declaration forms to...

  1. 15 CFR 712.5 - Annual declaration requirements for facilities engaged in the production of Schedule 1 chemicals...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...)(2) of this section if you produced at your facility in excess of 100 grams aggregate of Schedule 1... you will produce at your facility more than 100 grams aggregate of Schedule 1 chemicals in the next... result in production of more than 100 grams aggregate of Schedule 1 chemicals. (b) Declaration forms to...

  2. 15 CFR 712.5 - Annual declaration requirements for facilities engaged in the production of Schedule 1 chemicals...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...)(2) of this section if you produced at your facility in excess of 100 grams aggregate of Schedule 1... you will produce at your facility more than 100 grams aggregate of Schedule 1 chemicals in the next... result in production of more than 100 grams aggregate of Schedule 1 chemicals. (b) Declaration forms to...

  3. An integrated assessment of location-dependent scaling for microalgae biofuel production facilities

    DOE PAGES

    Coleman, André M.; Abodeely, Jared M.; Skaggs, Richard L.; ...

    2014-06-19

    Successful development of a large-scale microalgae-based biofuels industry requires comprehensive analysis and understanding of the feedstock supply chain—from facility siting and design through processing and upgrading of the feedstock to a fuel product. The evolution from pilot-scale production facilities to energy-scale operations presents many multi-disciplinary challenges, including a sustainable supply of water and nutrients, operational and infrastructure logistics, and economic competitiveness with petroleum-based fuels. These challenges are partially addressed by applying the Integrated Assessment Framework (IAF) – an integrated multi-scale modeling, analysis, and data management suite – to address key issues in developing and operating an open-pond microalgae production facility.more » This is done by analyzing how variability and uncertainty over space and through time affect feedstock production rates, and determining the site-specific “optimum” facility scale to minimize capital and operational expenses. This approach explicitly and systematically assesses the interdependence of biofuel production potential, associated resource requirements, and production system design trade-offs. To provide a baseline analysis, the IAF was applied in this paper to a set of sites in the southeastern U.S. with the potential to cumulatively produce 5 billion gallons per year. Finally, the results indicate costs can be reduced by scaling downstream processing capabilities to fit site-specific growing conditions, available and economically viable resources, and specific microalgal strains.« less

  4. A modern depleted uranium manufacturing facility

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zagula, T.A.

    1995-07-01

    The Specific Manufacturing Capabilities (SMC) Project located at the Idaho National Engineering Laboratory (INEL) and operated by Lockheed Martin Idaho Technologies Co. (LMIT) for the Department of Energy (DOE) manufactures depleted uranium for use in the U.S. Army MIA2 Abrams Heavy Tank Armor Program. Since 1986, SMC has fabricated more than 12 million pounds of depleted uranium (DU) products in a multitude of shapes and sizes with varying metallurgical properties while maintaining security, environmental, health and safety requirements. During initial facility design in the early 1980`s, emphasis on employee safety, radiation control and environmental consciousness was gaining momentum throughout themore » DOE complex. This fact coupled with security and production requirements forced design efforts to focus on incorporating automation, local containment and computerized material accountability at all work stations. The result was a fully automated production facility engineered to manufacture DU armor packages with virtually no human contact while maintaining security, traceability and quality requirements. This hands off approach to handling depleted uranium resulted in minimal radiation exposures and employee injuries. Construction of the manufacturing facility was complete in early 1986 with the first armor package certified in October 1986. Rolling facility construction was completed in 1987 with the first certified plate produced in the fall of 1988. Since 1988 the rolling and manufacturing facilities have delivered more than 2600 armor packages on schedule with 100% final product quality acceptance. During this period there was an annual average of only 2.2 lost time incidents and a single individual maximum radiation exposure of 150 mrem. SMC is an example of designing and operating a facility that meets regulatory requirements with respect to national security, radiation control and personnel safety while achieving production schedules and product quality.« less

  5. 44 CFR 331.5 - Production facilities.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Production facilities. 331.5 Section 331.5 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF... and essential economic and strategic factors. ...

  6. 40 CFR 60.420 - Applicability and designation of affected facility.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... within an ammonium sulfate manufacturing plant in the caprolactam by-product, synthetic, and coke oven by-product sectors of the ammonium sulfate industry. (b) Any facility under paragraph (a) of this section...

  7. Production Facility SCADA Design Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Dale, Gregory E.; Holloway, Michael Andrew; Baily, Scott A.

    2015-03-23

    The following report covers FY 14 activities to develop supervisory control and data acquisition (SCADA) system for the Northstar Moly99 production facility. The goal of this effort is to provide Northstar with a baseline system design.

  8. Revalidation of the NASA Ames 11-by 11-Foot Transonic Wind Tunnel with a Commercial Airplane Model

    NASA Technical Reports Server (NTRS)

    Kmak, Frank J.; Hudgins, M.; Hergert, D.; George, Michael W. (Technical Monitor)

    2001-01-01

    The 11-By 11-Foot Transonic leg of the Unitary Plan Wind Tunnel (UPWT) was modernized to improve tunnel performance, capability, productivity, and reliability. Wind tunnel tests to demonstrate the readiness of the tunnel for a return to production operations included an Integrated Systems Test (IST), calibration tests, and airplane validation tests. One of the two validation tests was a 0.037-scale Boeing 777 model that was previously tested in the 11-By 11-Foot tunnel in 1991. The objective of the validation tests was to compare pre-modernization and post-modernization results from the same airplane model in order to substantiate the operational readiness of the facility. Evaluation of within-test, test-to-test, and tunnel-to-tunnel data repeatability were made to study the effects of the tunnel modifications. Tunnel productivity was also evaluated to determine the readiness of the facility for production operations. The operation of the facility, including model installation, tunnel operations, and the performance of tunnel systems, was observed and facility deficiency findings generated. The data repeatability studies and tunnel-to-tunnel comparisons demonstrated outstanding data repeatability and a high overall level of data quality. Despite some operational and facility problems, the validation test was successful in demonstrating the readiness of the facility to perform production airplane wind tunnel%, tests.

  9. Recent Productivity Improvements to the National Transonic Facility

    NASA Technical Reports Server (NTRS)

    Popernack, Thomas G., Jr.; Sydnor, George H.

    1998-01-01

    Productivity gains have recently been made at the National Transonic Facility wind tunnel at NASA Langley Research Center. A team was assigned to assess and set productivity goals to achieve the desired operating cost and output of the facility. Simulations have been developed to show the sensitivity of selected process productivity improvements in critical areas to reduce overall test cycle times. The improvements consist of an expanded liquid nitrogen storage system, a new fan drive, a new tunnel vent stack heater, replacement of programmable logic controllers, an increased data communications speed, automated test sequencing, and a faster model changeout system. Where possible, quantifiable results of these improvements are presented. Results show that in most cases, improvements meet the productivity gains predicted by the simulations.

  10. 9 CFR 592.95 - Facilities and equipment to be furnished for use of inspection program personnel in performing...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 9 Animals and Animal Products 2 2012-01-01 2012-01-01 false Facilities and equipment to be furnished for use of inspection program personnel in performing service. 592.95 Section 592.95 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE EGG PRODUCTS INSPECTION VOLUNTARY INSPECTION OF EGG PRODUCTS Performanc...

  11. 9 CFR 592.95 - Facilities and equipment to be furnished for use of inspection program personnel in performing...

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 9 Animals and Animal Products 2 2013-01-01 2013-01-01 false Facilities and equipment to be furnished for use of inspection program personnel in performing service. 592.95 Section 592.95 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE EGG PRODUCTS INSPECTION VOLUNTARY INSPECTION OF EGG PRODUCTS Performanc...

  12. 9 CFR 592.95 - Facilities and equipment to be furnished for use of inspection program personnel in performing...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 9 Animals and Animal Products 2 2011-01-01 2011-01-01 false Facilities and equipment to be furnished for use of inspection program personnel in performing service. 592.95 Section 592.95 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE EGG PRODUCTS INSPECTION VOLUNTARY INSPECTION OF EGG PRODUCTS Performanc...

  13. 9 CFR 592.95 - Facilities and equipment to be furnished for use of inspection program personnel in performing...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 9 Animals and Animal Products 2 2014-01-01 2014-01-01 false Facilities and equipment to be furnished for use of inspection program personnel in performing service. 592.95 Section 592.95 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE EGG PRODUCTS INSPECTION VOLUNTARY INSPECTION OF EGG PRODUCTS Performanc...

  14. Analysis of federal and state policies and environmental issues for bioethanol production facilities.

    PubMed

    McGee, Chandra; Chan Hilton, Amy B

    2011-03-01

    The purpose of this work was to investigate incentives and barriers to fuel ethanol production from biomass in the U.S. during the past decade (2000-2010). In particular, we examine the results of policies and economic conditions during this period by way of cellulosic ethanol activity in four selected states with the potential to produce different types of feedstocks (i.e., sugar, starch, and cellulosic crops) for ethanol production (Florida, California, Hawaii, and Iowa). Two of the four states, Iowa and California, currently have commercial ethanol production facilities in operation using corn feedstocks. While several companies have proposed commercial scale facilities in Florida and Hawaii, none are operating to date. Federal and state policies and incentives, potential for feedstock production and conversion to ethanol and associated potential environmental impacts, and environmental regulatory conditions among the states were investigated. Additionally, an analysis of proposed and operational ethanol production facilities provided evidence that a combination of these policies and incentives along with the ability to address environmental issues and regulatory environment and positive economic conditions all impact ethanol production. The 2000-2010 decade saw the rise of the promise of cellulosic ethanol. Federal and state policies were enacted to increase ethanol production. Since the initial push for development, expansion of cellulosic ethanol production has not happened as quickly as predicted. Government and private funding supported the development of ethanol production facilities, which peaked and then declined by the end of the decade. Although there are technical issues that remain to be solved to more efficiently convert cellulosic material to ethanol while reducing environmental impacts, the largest barriers to increasing ethanol production appear to be related to government policies, economics, and logistical issues. The numerous federal and state policies do not effectively give investors confidence to commit to the construction and long-term operation of facilities under current economic conditions. Additional changes in policy and breakthroughs in technology and logistics will be required to address these hurdles to increases in ethanol production in the U.S. in the next decade.

  15. 9 CFR 2.37 - Federal research facilities.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 9 Animals and Animal Products 1 2012-01-01 2012-01-01 false Federal research facilities. 2.37... AGRICULTURE ANIMAL WELFARE REGULATIONS Research Facilities § 2.37 Federal research facilities. Each Federal research facility shall establish an Institutional Animal Care and Use Committee which shall have the same...

  16. 9 CFR 2.37 - Federal research facilities.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 9 Animals and Animal Products 1 2013-01-01 2013-01-01 false Federal research facilities. 2.37... AGRICULTURE ANIMAL WELFARE REGULATIONS Research Facilities § 2.37 Federal research facilities. Each Federal research facility shall establish an Institutional Animal Care and Use Committee which shall have the same...

  17. 9 CFR 3.76 - Indoor housing facilities.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 9 Animals and Animal Products 1 2011-01-01 2011-01-01 false Indoor housing facilities. 3.76... Transportation of Nonhuman Primates 2 Facilities and Operating Standards § 3.76 Indoor housing facilities. (a) Heating, cooling, and temperature. Indoor housing facilities must be sufficiently heated and cooled when...

  18. 9 CFR 2.37 - Federal research facilities.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 9 Animals and Animal Products 1 2014-01-01 2014-01-01 false Federal research facilities. 2.37... AGRICULTURE ANIMAL WELFARE REGULATIONS Research Facilities § 2.37 Federal research facilities. Each Federal research facility shall establish an Institutional Animal Care and Use Committee which shall have the same...

  19. 9 CFR 351.10 - Facilities.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Facilities. 351.10 Section 351.10... CERTIFICATION CERTIFICATION OF TECHNICAL ANIMAL FATS FOR EXPORT Facilities and Operations § 351.10 Facilities. (a) Facilities for the preparation, identification, and storage of the technical animal fat to be...

  20. 9 CFR 2.37 - Federal research facilities.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 9 Animals and Animal Products 1 2011-01-01 2011-01-01 false Federal research facilities. 2.37... AGRICULTURE ANIMAL WELFARE REGULATIONS Research Facilities § 2.37 Federal research facilities. Each Federal research facility shall establish an Institutional Animal Care and Use Committee which shall have the same...

  1. National Biomedical Tracer Facility. Project definition study

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Schafer, R.

    We request a $25 million government-guaranteed, interest-free loan to be repaid over a 30-year period for construction and initial operations of a cyclotron-based National Biomedical Tracer Facility (NBTF) in North Central Texas. The NBTF will be co-located with a linear accelerator-based commercial radioisotope production facility, funded by the private sector at approximately $28 million. In addition, research radioisotope production by the NBTF will be coordinated through an association with an existing U.S. nuclear reactor center that will produce research and commercial radioisotopes through neutron reactions. The combined facilities will provide the full range of technology for radioisotope production and research:more » fast neutrons, thermal neutrons, and particle beams (H{sup -}, H{sup +}, and D{sup +}). The proposed NBTF facility includes an 80 MeV, 1 mA H{sup -} cyclotron that will produce proton-induced (neutron deficient) research isotopes.« less

  2. Prevalence of Clostridium difficile in uncooked ground meat products from Pittsburgh, Pennsylvania.

    PubMed

    Curry, Scott R; Marsh, Jane W; Schlackman, Jessica L; Harrison, Lee H

    2012-06-01

    The prevalence of Clostridium difficile in retail meat samples has varied widely. The food supply may be a source for C. difficile infections. A total of 102 ground meat and sausage samples from 3 grocers in Pittsburgh, PA, were cultured for C. difficile. Brand A pork sausages were resampled between May 2011 and January 2012. Two out of 102 (2.0%) meat products initially sampled were positive for C. difficile; both were pork sausage from brand A from the same processing facility (facility A). On subsequent sampling of brand A products, 10/19 samples from processing facility A and 1/10 samples from 3 other facilities were positive for C. difficile. The isolates recovered were inferred ribotype 078, comprising 6 genotypes. The prevalence of C. difficile in retail meat may not be as high as previously reported in North America. When contamination occurs, it may be related to events at processing facilities.

  3. Site maps and facilities listings

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1993-11-01

    In September 1989, a Memorandum of Agreement among DOE offices regarding the environmental management of DOE facilities was signed by appropriate Assistant Secretaries and Directors. This Memorandum of Agreement established the criteria for EM line responsibility. It stated that EM would be responsible for all DOE facilities, operations, or sites (1) that have been assigned to DOE for environmental restoration and serve or will serve no future production need; (2) that are used for the storage, treatment, or disposal of hazardous, radioactive, and mixed hazardous waste materials that have been properly characterized, packaged, and labelled, but are not used formore » production; (3) that have been formally transferred to EM by another DOE office for the purpose of environmental restoration and the eventual return to service as a DOE production facility; or (4) that are used exclusively for long-term storage of DOE waste material and are not actively used for production, with the exception of facilities, operations, or sites under the direction of the DOE Office of Civilian Radioactive Waste Management. As part of the implementation of the Memorandum of Agreement, Field Offices within DOE submitted their listings of facilities, systems, operation, and sites for which EM would have line responsibility. It is intended that EM facility listings will be revised on a yearly basis so that managers at all levels will have a valid reference for the planning, programming, budgeting and execution of EM activities.« less

  4. Cogeneration systems and processes for treating hydrocarbon containing formations

    DOEpatents

    Vinegar, Harold J [Bellaire, TX; Fowler, Thomas David [Houston, TX; Karanikas, John Michael [Houston, TX

    2009-12-29

    A system for treating a hydrocarbon containing formation includes a steam and electricity cogeneration facility. At least one injection well is located in a first portion of the formation. The injection well provides steam from the steam and electricity cogeneration facility to the first portion of the formation. At least one production well is located in the first portion of the formation. The production well in the first portion produces first hydrocarbons. At least one electrical heater is located in a second portion of the formation. At least one of the electrical heaters is powered by electricity from the steam and electricity cogeneration facility. At least one production well is located in the second portion of the formation. The production well in the second portion produces second hydrocarbons. The steam and electricity cogeneration facility uses the first hydrocarbons and/or the second hydrocarbons to generate electricity.

  5. Efficiency and cost advantages of an advanced-technology nuclear electrolytic hydrogen-energy production facility

    NASA Technical Reports Server (NTRS)

    Donakowski, T. D.; Escher, W. J. D.; Gregory, D. P.

    1977-01-01

    The concept of an advanced-technology (viz., 1985 technology) nuclear-electrolytic water electrolysis facility was assessed for hydrogen production cost and efficiency expectations. The facility integrates (1) a high-temperature gas-cooled nuclear reactor (HTGR) operating a binary work cycle, (2) direct-current (d-c) electricity generation via acyclic generators, and (3) high-current-density, high-pressure electrolyzers using a solid polymer electrolyte (SPE). All subsystems are close-coupled and optimally interfaced for hydrogen production alone (i.e., without separate production of electrical power). Pipeline-pressure hydrogen and oxygen are produced at 6900 kPa (1000 psi). We found that this advanced facility would produce hydrogen at costs that were approximately half those associated with contemporary-technology nuclear electrolysis: $5.36 versus $10.86/million Btu, respectively. The nuclear-heat-to-hydrogen-energy conversion efficiency for the advanced system was estimated as 43%, versus 25% for the contemporary system.

  6. Nonterrestrial utilization of materials: Automated space manufacturing facility

    NASA Technical Reports Server (NTRS)

    1982-01-01

    Four areas related to the nonterrestrial use of materials are included: (1) material resources needed for feedstock in an orbital manufacturing facility, (2) required initial components of a nonterrestrial manufacturing facility, (3) growth and productive capability of such a facility, and (4) automation and robotics requirements of the facility.

  7. Production cost of a real microalgae production plant and strategies to reduce it.

    PubMed

    Acién, F G; Fernández, J M; Magán, J J; Molina, E

    2012-01-01

    The cost analysis of a real facility for the production of high value microalgae biomass is presented. The facility is based on ten 3 m3 tubular photobioreactors operated in continuous mode for 2 years, data of Scenedesmus almeriensis productivity but also of nutrients and power consumption from this facility being used. The yield of the facility was close to maximum expected for the location of Almería, the annual production capacity being 3.8 t/year (90 t/ha·year) and the photosynthetic efficiency being 3.6%. The production cost was 69 €/kg. Economic analysis shows that labor and depreciation are the major factors contributing to this cost. Simplification of the technology and scale-up to a production capacity of 200 t/year allows to reduce the production cost up to 12.6 €/kg. Moreover, to reduce the microalgae production cost to approaches the energy or commodities markets it is necessary to reduce the photobioreactor cost (by simplifying its design or materials used), use waste water and flue gases, and reduce the power consumption and labor required for the production step. It can be concluded that although it has been reported that production of biofuels from microalgae is relatively close to being economically feasible, data here reported demonstrated that to achieve it by using the current production technologies, it is necessary to substantially reduce their costs and to operate them near their optimum values. Copyright © 2012 Elsevier Inc. All rights reserved.

  8. Methicillin-Resistant Staphylococcus aureus in Pork Production Shower Facilities ▿

    PubMed Central

    Leedom Larson, Kerry R.; Harper, Abby L.; Hanson, Blake M.; Male, Michael J.; Wardyn, Shylo E.; Dressler, Anne E.; Wagstrom, Elizabeth A.; Tendolkar, Shaliesh; Diekema, Daniel J.; Donham, Kelley J.; Smith, Tara C.

    2011-01-01

    As methicillin-resistant Staphylococcus aureus (MRSA) has been found in pigs, we sought to determine if MRSA is present in pork production shower facilities. In two production systems tested, 3% and 26% of shower samples were positive for MRSA. spa types identified included t034, t189, t753, and t1746. PMID:21097587

  9. COMPARISON OF AN INNOVATIVE NONLINEAR ALGORITHM TO CLASSICAL LEAST SQUARES FOR ANALYZING OPEN-PATH FOURIER TRANSFORM INFRARED SPECTRA COLLECTED AT A CONCENTRATED SWINE PRODUCTION FACILITY

    EPA Science Inventory

    Open-path Fourier transform infrared (OP/FTIR) spectrometry was used to measure the concentrations of ammonia, methane, and other atmospheric gases at an integrated swine production facility. The concentration-pathlength products of the target gases at this site often exceeded th...

  10. 9 CFR 592.95 - Facilities and equipment to be furnished for use of inspection program personnel in performing...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Facilities and equipment to be furnished for use of inspection program personnel in performing service. 592.95 Section 592.95 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE EGG PRODUCTS INSPECTION...

  11. High power neutron production targets

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wender, S.

    1996-06-01

    The author describes issues of concern in the design of targets and associated systems for high power neutron production facilities. The facilities include uses for neutron scattering, accelerator driven transmutation, accelerator production of tritium, short pulse spallation sources, and long pulse spallation sources. Each of these applications requires a source with different design needs and consequently different implementation in practise.

  12. Strategic interaction among hospitals and nursing facilities: the efficiency effects of payment systems and vertical integration.

    PubMed

    Banks, D; Parker, E; Wendel, J

    2001-03-01

    Rising post-acute care expenditures for Medicare transfer patients and increasing vertical integration between hospitals and nursing facilities raise questions about the links between payment system structure, the incentive for vertical integration and the impact on efficiency. In the United States, policy-makers are responding to these concerns by initiating prospective payments to nursing facilities, and are exploring the bundling of payments to hospitals. This paper develops a static profit-maximization model of the strategic interaction between the transferring hospital and a receiving nursing facility. This model suggests that the post-1984 system of prospective payment for hospital care, coupled with nursing facility payments that reimburse for services performed, induces inefficient under-provision of hospital services and encourages vertical integration. It further indicates that the extension of prospective payment to nursing facilities will not eliminate the incentive to vertically integrate, and will not result in efficient production unless such integration takes place. Bundling prospective payments for hospitals and nursing facilities will neither remove the incentive for vertical integration nor induce production efficiency without such vertical integration. However, bundled payment will induce efficient production, with or without vertical integration, if nursing facilities are reimbursed for services performed. Copyright 2001 John Wiley & Sons, Ltd.

  13. 40 CFR 60.260 - Applicability and designation of affected facility.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... affected facility. 60.260 Section 60.260 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Performance for Ferroalloy Production Facilities § 60.260 Applicability and designation of affected facility..., ferrochrome silicon, silvery iron, high-carbon ferrochrome, charge chrome, standard ferromanganese...

  14. 40 CFR 60.260 - Applicability and designation of affected facility.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... affected facility. 60.260 Section 60.260 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Performance for Ferroalloy Production Facilities § 60.260 Applicability and designation of affected facility..., ferrochrome silicon, silvery iron, high-carbon ferrochrome, charge chrome, standard ferromanganese...

  15. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Brink, J.

    Crude oil (c. 10,700 BOPD) was produced through temporary topside facilities in the Rolf Field offshore Denmark from January 7th to September 17th, 1986. These simple, unmanned and remote controlled facilities were a low cost solution to a problem caused by delays of the permanent topside facilities. Project execution time was two months from start of conceptual design until start-up of oil production. Installation works were performed from a jack-up drilling rig - in part simultaneously with drilling operations. Materials and equipment installed were obtained with very short delivery times. The facilties which were certified by a Certification Society andmore » approved by the Danish Authoritites included all necessary safety features. Total costs for the facilities amounted to c. 1 million US$ (excl. rig time for installation). Due to simplicity high reliability of the production system was obtained. Availability of the facilities for the entire period from start-up was 99.6 percent. The facilities were manned 3.2 percent of the total operating time mainly due to wireline work for reservoir monitoring. It is considered that the experience with the concept applied for the early production from the Rolf Field could form the basis for more simple and cost effective topside facilities for minor offshore fields.« less

  16. COMMERCIAL DEMONSTRATION OF THE MANUFACTURED AGGREGATE PROCESSING TECHNOLOGY UTILIZING SPRAY DRYER ASH

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Roy Scandrol

    2003-04-01

    Universal Aggregates, LLC proposes to design, construct and operate a lightweight aggregate manufacturing plant at the Birchwood Power Facility in King George, Virginia. The installation and start-up expenses for the Birchwood Aggregate Facility are $19.5 million. The DOE share is $7.2 million (37%) and the Universal Aggregates share is $12.3 (63%). The project team consists of CONSOL Energy Inc., P.J. Dick, Inc., SynAggs, LLC, and Universal Aggregates, LLC. The Birchwood Facility will transform 115,000 tons per year of spray dryer by-products that are currently being disposed of in an offsite landfill into 167,000 tons of a useful product, lightweight aggregatesmore » that can be used to manufacture lightweight aggregates that can be used to manufacture lightweight and medium weight masonry blocks. In addition to the environmental benefits, the Birchwood Facility will create eight (8) manufacturing jobs plus additional employment in the local trucking industry to deliver the aggregate to customers or reagents to the facility. A successful demonstration would lead to additional lightweight aggregate manufacturing facilities in the United States. There are currently twenty-one (21) spray dryer facilities operating in the United States that produce an adequate amount of spray dryer by-product to economically justify the installation of a lightweight aggregate manufacturing facility. Industry sources believe that as additional scrubbing is required, dry flue gas desulfurization (FGD) technologies will be the technology of choice. Letters from potential lightweight aggregate customers indicate that there is a market for the product once the commercialization barriers are eliminated by this demonstration project.« less

  17. COMMERCIAL DEMONSTRATION OF THE MANUFACTURED AGGREGATE PROCESSING TECHNOLOGY UTILIZING SPRAY DRYER ASH

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Roy Scandrol

    2003-10-01

    Universal Aggregates, LLC proposes to design, construct and operate a lightweight aggregate manufacturing plant at the Birchwood Power Facility in King George, Virginia. The installation and start-up expenses for the Birchwood Aggregate Facility are $19.5 million. The DOE share is $7.2 million (37%) and the Universal Aggregates share is $12.3 (63%). The project team consists of CONSOL Energy Inc., P.J. Dick, Inc., SynAggs, LLC, and Universal Aggregates, LLC. The Birchwood Facility will transform 115,000 tons per year of spray dryer by-products that are currently being disposed of in an offsite landfill into 167,000 tons of a useful product, lightweight aggregatesmore » that can be used to manufacture lightweight aggregates that can be used to manufacture lightweight and medium weight masonry blocks. In addition to the environmental benefits, the Birchwood Facility will create nine (9) manufacturing jobs plus additional employment in the local trucking industry to deliver the aggregate to customers or reagents to the facility. A successful demonstration would lead to additional lightweight aggregate manufacturing facilities in the United States. There are currently twenty-one (21) spray dryer facilities operating in the United States that produce an adequate amount of spray dryer by-product to economically justify the installation of a lightweight aggregate manufacturing facility. Industry sources believe that as additional scrubbing is required, dry FGD technologies will be the technology of choice. Letters from potential lightweight aggregate customers indicate that there is a market for the product once the commercialization barriers are eliminated by this demonstration project.« less

  18. Lean coding machine. Facilities target productivity and job satisfaction with coding automation.

    PubMed

    Rollins, Genna

    2010-07-01

    Facilities are turning to coding automation to help manage the volume of electronic documentation, streamlining workflow, boosting productivity, and increasing job satisfaction. As EHR adoption increases, computer-assisted coding may become a necessity, not an option.

  19. 40 CFR 49.146 - Recordkeeping requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... ASSISTANCE INDIAN COUNTRY: AIR QUALITY PLANNING AND MANAGEMENT General Federal Implementation Plan Provisions Federal Implementation Plan for Oil and Natural Gas Production Facilities, Fort Berthold Indian... the oil and natural gas production facility each time the oil is unloaded from the produced oil...

  20. Ongoing nationwide outbreak of Salmonella Agona associated with internationally distributed infant milk products, France, December 2017.

    PubMed

    Jourdan-da Silva, Nathalie; Fabre, Laetitia; Robinson, Eve; Fournet, Nelly; Nisavanh, Athinna; Bruyand, Mathias; Mailles, Alexandra; Serre, Estelle; Ravel, Magali; Guibert, Véronique; Issenhuth-Jeanjean, Sylvie; Renaudat, Charlotte; Tourdjman, Mathieu; Septfons, Alexandra; de Valk, Henriette; Le Hello, Simon

    2018-01-01

    On 1 December 2017, an outbreak of Salmonella Agona infections among infants was identified in France. To date, 37 cases (median age: 4 months) and two further international cases have been confirmed. Five different infant milk products manufactured at one facility were implicated. On 2 and 10 December, the company recalled the implicated products; on 22 December, all products processed at the facility since February 2017. Trace-forward investigations indicated product distribution to 66 countries.

  1. Ergonomics and simulation-based approach in improving facility layout

    NASA Astrophysics Data System (ADS)

    Abad, Jocelyn D.

    2018-02-01

    The use of the simulation-based technique in facility layout has been a choice in the industry due to its convenience and efficient generation of results. Nevertheless, the solutions generated are not capable of addressing delays due to worker's health and safety which significantly impact overall operational efficiency. It is, therefore, critical to incorporate ergonomics in facility design. In this study, workstation analysis was incorporated into Promodel simulation to improve the facility layout of a garment manufacturing. To test the effectiveness of the method, existing and improved facility designs were measured using comprehensive risk level, efficiency, and productivity. Results indicated that the improved facility layout generated a decrease in comprehensive risk level and rapid upper limb assessment score; an increase of 78% in efficiency and 194% increase in productivity compared to existing design and thus proved that the approach is effective in attaining overall facility design improvement.

  2. Methods and systems for the production of hydrogen

    DOEpatents

    Oh, Chang H [Idaho Falls, ID; Kim, Eung S [Ammon, ID; Sherman, Steven R [Augusta, GA

    2012-03-13

    Methods and systems are disclosed for the production of hydrogen and the use of high-temperature heat sources in energy conversion. In one embodiment, a primary loop may include a nuclear reactor utilizing a molten salt or helium as a coolant. The nuclear reactor may provide heat energy to a power generation loop for production of electrical energy. For example, a supercritical carbon dioxide fluid may be heated by the nuclear reactor via the molten salt and then expanded in a turbine to drive a generator. An intermediate heat exchange loop may also be thermally coupled with the primary loop and provide heat energy to one or more hydrogen production facilities. A portion of the hydrogen produced by the hydrogen production facility may be diverted to a combustor to elevate the temperature of water being split into hydrogen and oxygen by the hydrogen production facility.

  3. Scientific Ballooning in India - Recent Developments

    NASA Astrophysics Data System (ADS)

    Manchanda, R. K.; Srinivasan, S.; Subbarao, J. V.

    Established in 1972, the National Balloon Facility operated by TIFR in Hyderabad, India is is a unique facility in the country, which provides a complete solution in scientific ballooning. It is also one of its kind in the world since it combines both, the in-house balloon production and a complete flight support for scientific ballooning. With a large team working through out the year to design, fabricate and launch scientific balloons, the Hyderabad Facility is a unique centre of expertise where the balloon design, Research and Development, the production and launch facilities are located under one roof. Our balloons are manufactured from 100% indigenous components. The mission specific balloon design, high reliability control and support instrumentation, in-house competence in tracking, telemetry, telecommand, data processing, system design and mechanics is a hallmark of the Hyderabad balloon facility. In the past few years we have executed a major programme of upgradation of different components of balloon production, telemetry and telecommand hardware and various support facilities. This paper focuses on our increased capability of balloon production of large sizes up to size of 780,000 M^3 using Antrix film, development of high strength balloon load tapes with the breaking strength of 182 kg, and the recent introduction of S-band telemetry and a commandable timer cut-off unit in the flight hardware. A summary of the various flights conducted in recent years will be presented along with the plans for new facilities.

  4. 9 CFR 314.1 - Disposition of condemned products at official establishments having tanking facilities; sealing...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Disposition of condemned products at official establishments having tanking facilities; sealing of tanks. 314.1 Section 314.1 Animals and Animal... § 314.3 before leaving such establishment. (b) The seals of tanks shall be broken only by a Program...

  5. 9 CFR 314.1 - Disposition of condemned products at official establishments having tanking facilities; sealing...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 9 Animals and Animal Products 2 2011-01-01 2011-01-01 false Disposition of condemned products at official establishments having tanking facilities; sealing of tanks. 314.1 Section 314.1 Animals and Animal... § 314.3 before leaving such establishment. (b) The seals of tanks shall be broken only by a Program...

  6. Process control and dosimetry in a multipurpose irradiation facility

    NASA Astrophysics Data System (ADS)

    Cabalfin, E. G.; Lanuza, L. G.; Solomon, H. M.

    1999-08-01

    Availability of the multipurpose irradiation facility at the Philippine Nuclear Research Institute has encouraged several local industries to use gamma radiation for sterilization or decontamination of various products. Prior to routine processing, dose distribution studies are undertaken for each product and product geometry. During routine irradiation, dosimeters are placed at the minimum and maximum dose positions of a process load.

  7. 12 CFR 555.200 - How may I use or participate with others to use electronic means and facilities?

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... sell, or participate with others to market and sell, electronic capacities and by-products to third-parties, if you acquired or developed these capacities and by-products in good faith as part of providing..., electronic means or facilities to perform any function, or provide any product or service, as part of an...

  8. The RIB production target for the SPES project

    NASA Astrophysics Data System (ADS)

    Monetti, Alberto; Andrighetto, Alberto; Petrovich, Carlo; Manzolaro, Mattia; Corradetti, Stefano; Scarpa, Daniele; Rossetto, Francesco; Martinez Dominguez, Fernando; Vasquez, Jesus; Rossignoli, Massimo; Calderolla, Michele; Silingardi, Roberto; Mozzi, Aldo; Borgna, Francesca; Vivian, Gianluca; Boratto, Enrico; Ballan, Michele; Prete, Gianfranco; Meneghetti, Giovanni

    2015-10-01

    Facilities making use of the Isotope Separator On-Line (ISOL) method for the production of Radioactive Ion Beams (RIB) attract interest because they can be used for nuclear structure and reaction studies, astrophysics research and interdisciplinary applications. The ISOL technique is based on the fast release of the nuclear reaction products from the chosen target material together with their ionization into short-lived nuclei beams. Within this context, the SPES (Selective Production of Exotic Species) facility is now under construction in Italy at INFN-LNL (Istituto Nazionale di Fisica Nucleare — Laboratori Nazionali di Legnaro). The SPES facility will produce RIBs mainly from n-rich isotopes obtained by a 40 MeV cyclotron proton beam (200 μA) directly impinging on a uranium carbide multi-foil fission target. The aim of this work is to describe and update, from a comprehensive point of view, the most important results obtained by the analysis of the on-line behavior of the SPES production target assembly. In particular an improved target configuration has been studied by comparing different codes and physics models: the thermal analyses and the isotope production are re-evaluated. Then some consequent radioprotection aspects, which are essential for the installation and operation of the facility, are presented.

  9. Towards Understanding the Impact of Production Techniques and Regulations on Widely Varying Methane Emission Rates in Western Basins

    NASA Astrophysics Data System (ADS)

    Robertson, A.; Edie, R.; Soltis, J.; Field, R. A.; Murphy, S. M.

    2017-12-01

    Recent airborne and mobile lab-based studies by our group and others have demonstrated that production-normalized emission rates of methane can vary dramatically between different Western basins. Three oil and gas basins that are geographically near one another and have relatively similar production characteristics (all three basins produce a mix of natural gas and condensate) have starkly different production-normalized methane emission rates at both the facility and basin-wide levels. This presentation will review previously published data on methane emissions from these basins (Denver Julesburg, Uintah, and Upper Green River) and present new measurement work supporting and expanding upon previous estimates. Beyond this, we use facility level data emissions data combined with information about the date of last upgrade to determine what impact regulations have had on methane emission rates from facilities within the basins. We also investigate what impact different approaches to production may have, in particular the role of having many individual wells processed at a central facility with high throughput is analyzed in terms of its impact on methane emissions.

  10. Towards Understanding the Impact of Production Techniques and Regulations on Widely Varying Methane Emission Rates in Western Basins

    NASA Astrophysics Data System (ADS)

    Regayre, L. A.; Johnson, J. S.; Yoshioka, M.; Pringle, K.; Sexton, D.; Booth, B.; Mann, G.; Lee, L.; Bellouin, N.; Lister, G. M. S.; Johnson, C.; Johnson, B. T.; Mollard, J.; Carslaw, K. S.

    2016-12-01

    Recent airborne and mobile lab-based studies by our group and others have demonstrated that production-normalized emission rates of methane can vary dramatically between different Western basins. Three oil and gas basins that are geographically near one another and have relatively similar production characteristics (all three basins produce a mix of natural gas and condensate) have starkly different production-normalized methane emission rates at both the facility and basin-wide levels. This presentation will review previously published data on methane emissions from these basins (Denver Julesburg, Uintah, and Upper Green River) and present new measurement work supporting and expanding upon previous estimates. Beyond this, we use facility level data emissions data combined with information about the date of last upgrade to determine what impact regulations have had on methane emission rates from facilities within the basins. We also investigate what impact different approaches to production may have, in particular the role of having many individual wells processed at a central facility with high throughput is analyzed in terms of its impact on methane emissions.

  11. Hazardous Waste Cleanup: BASF Agricultural Products of Puerto Rico in Manati, Puerto Rico

    EPA Pesticide Factsheets

    BASF Agricultural Products (BASF) of Puerto Rico facility manufacturing operations have been dedicated to the formulation of liquid herbicides since February 2009. As the facility is currently operating, access to its premises is controlled by security at

  12. PERF - A new approach to the experimental study of radiative aerodynamic heating and radiative blockage by ablation products

    NASA Technical Reports Server (NTRS)

    Walberg, G.

    1974-01-01

    The present work describes a facility designed to validate the various aspects of radiative flow field theory, including the absorption of shock layer radiation by ablation products. The facility is capable of producing radiation with a spectrum similar to that of an entry vehicle shock layer and is designed to allow measurements at vacuum ultraviolet wavelengths where the most significant absorption by ablation products is predicted to occur. The design concept of the facility is presented along with results of theoretical analyses carried out to assess its research potential. Experimental data obtained during tests that simulated earth and Venusian entry and in which simulated ablation products were injected into the stagnation region flow field are discussed.

  13. A Review of the Aging Process and Facilities Topic.

    PubMed

    Jornitz, Maik W

    2015-01-01

    Aging facilities have become a concern in the pharmaceutical and biopharmaceutical manufacturing industry, so much that task forces are formed by trade organizations to address the topic. Too often, examples of aging or obsolete equipment, unit operations, processes, or entire facilities have been encountered. Major contributors to this outcome are the failure to invest in new equipment, disregarding appropriate maintenance activities, and neglecting the implementation of modern technologies. In some cases, a production process is insufficiently modified to manufacture a new product in an existing process that was used to produce a phased-out product. In other instances, manufacturers expanded the facility or processes to fulfill increasing demand and the scaling occurred in a non-uniform manner, which led to non-optimal results. Regulatory hurdles of post-approval changes in the process may thwart companies' efforts to implement new technologies. As an example, some changes have required 4 years to gain global approval. This paper will address cases of aging processes and facilities aside from modernizing options. © PDA, Inc. 2015.

  14. Abatement of Xenon and Iodine Emissions from Medical Isotope Production Facilities

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Doll, Charles G.; Sorensen, Christina M.; Bowyer, Ted W.

    2014-04-01

    The capability of the International Monitoring System (IMS) to detect xenon from underground nuclear explosions is dependent on the radioactive xenon background. Adding to the background, medical isotope production (MIP) by fission releases several important xenon isotopes including xenon-133 and iodine-133 that decays to xenon-133. The amount of xenon released from these facilities may be equivalent to or exceed that released from an underground nuclear explosion. Thus the release of gaseous fission products within days of irradiation makes it difficult to distinguish MIP emissions from a nuclear explosion. In addition, recent shortages in molybdenum-99 have created interest and investment opportunitiesmore » to design and build new MIP facilities in the United States and throughout the world. Due to the potential increase in the number of MIP facilities, a discussion of abatement technologies provides insight into how the problem of emission control from MIP facilities can be tackled. A review of practices is provided to delineate methods useful for abatement of medical isotopes.« less

  15. Amorphous silicon photovoltaic manufacturing technology, phase 2A

    NASA Astrophysics Data System (ADS)

    Duran, G.; Mackamul, K.; Metcalf, D.

    1995-01-01

    Utility Power Group (UPG), and its lower-tier subcontractor, Advanced Photovoltaic Systems, Inc. (APS) have conducted efforts in developing their manufacturing lines. UPG has focused on the automation of encapsulation and termination processes developed in Phase 1. APS has focused on completion of the encapsulation and module design tasks, while continuing the process and quality control and automation projects. The goal is to produce 55 watt (stabilized) EP50 modules in a new facility. In the APS Trenton EUREKA manufacturing facility, APS has: (1) Developed high throughput lamination procedures; (2) Optimized existing module designs; (3) Developed new module designs for architectural applications; (4) Developed enhanced deposition parameter control; (5) Designed equipment required to manufacture new EUREKA modules developed during Phase II; (6) Improved uniformity of thin-film materials deposition; and (7) Improved the stabilized power output of the APS EP50 EUREKA module to 55 watts. In the APS Fairfield EUREKA manufacturing facility, APS has: (1) Introduced the new products developed under Phase 1 into the APS Fairfield EUREKA module production line; (2) Increased the extent of automation in the production line; (3) Introduced Statistical Process Control to the module production line; and (4) Transferred-progress made in the APS Trenton facility into the APS Fairfield facility.

  16. Longitudinal Comparison of the Microbiota During Klebsiella pneumoniae Carbapenemase-Producing Klebsiella pneumoniae (KPC-Kp) Acquisition in Long-Term Acute Care Hospital (LTACH) patients

    PubMed Central

    Seekatz, Anna; Bassis, Christine M; Lolans, Karen; Yelin, Rachel D; Moore, Nicholas M; Okamoto, Koh; Rhee, Yoona; Bell, Pamela; Dangana, Thelma; Sidimirova, Galina; Weinstein, Robert A; Fogg, Louis; Lin, Michael Y; Young, Vincent B; Hayden, Mary K

    2017-01-01

    Abstract Background Colonization with KPC-Kp precedes infection and represents a potential target for intervention. To identify microbial signatures associated with KPC-Kp acquisition, we conducted a prospective, longitudinal study of the fecal microbiota in LTACH patients at risk of acquiring KPC-Kp. Methods We collected admission and weekly rectal swab samples from patients admitted to one LTACH from May 2015 to May 2016. Patients were screened for KPC-Kp by PCR at each sampling time. KPC acquisition was confirmed by culture of KPC-Kp. To assess changes in the microbiota related to acquisition, we sequenced the 16S rRNA gene (V4 region) from collected rectal swabs. Diversity, intra-individual changes, and the relative abundance of the operational taxonomic unit (OTU) that contains KPC-Kp were compared in patients who were KPC-Kp negative upon admission and who had at least one additional swab sample collected. Results 318 patients (1247 samples) were eligible for analysis; 3.7 samples (mean) were collected per patient. Sixty-two patients (19.5%) acquired KPC-Kp (cases) and 256 patients remained negative for all carbapenem-resistant Enterobacteriaceae throughout their stay (controls). Median length of stay before KPC-Kp detection was 14.5 days. At time of KPC-Kp acquisition, levels of an Enterobacteriaceae OTU increased significantly compared with pre-acquisition samples and to samples from control patients (Wilcoxon test, P < 0.0001). Similarly, we observed a decrease in total diversity of the fecal microbiota at time of acquisition in cases (P < 0.01). Compared with controls, cases exhibited decreased intra-individual fecal microbiota similarity immediately prior to acquisition of KPC-Kp (P < 0.01). Comparison of microbial features at time of admission using random forest revealed a higher abundance of Enterococcus and Escherichia OTUs in controls vs cases. Conclusion We observed intra-individual changes in the fecal microbiota of case patients prior to acquisition of KPC-Kp. Compared with patients who did not acquire KPC-Kp, cases exhibited significant changes in microbiota diversity and increased abundance of potential KPC-Kp at acquisition. Our results suggest that shifts in the microbiota may precede colonization by KPC-Kp. Disclosures N. M. Moore, Cepheid: Research Contractor, Funded and provided reagents for associated research projects; R. A. Weinstein, OpGen: Receipt of donated laboratory services for project, Research support; CLorox: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Molnlycke: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Sage Products: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; M. Y. Lin, Sage, Inc.: receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; OpGen, Inc.: receipt of in-kind laboratory services, Conducting studies in healthcare facilities that are receiving contributed product; M. K. Hayden, OpGen, Inc.: Receipt of donated laboratory services for project, Research support; Clorox: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Molnlycke: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product; Sage Products: Receipt of contributed product, Conducting studies in healthcare facilities that are receiving contributed product.

  17. 40 CFR 49.146 - Recordkeeping requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Federal Implementation Plan for Oil and Natural Gas Production Facilities, Fort Berthold Indian...) Each owner or operator must maintain the following records: (1) The measured barrels of oil produced at the oil and natural gas production facility each time the oil is unloaded from the produced oil...

  18. Adjustment of automatic control systems of production facilities at coal processing plants using multivariant physico- mathematical models

    NASA Astrophysics Data System (ADS)

    Evtushenko, V. F.; Myshlyaev, L. P.; Makarov, G. V.; Ivushkin, K. A.; Burkova, E. V.

    2016-10-01

    The structure of multi-variant physical and mathematical models of control system is offered as well as its application for adjustment of automatic control system (ACS) of production facilities on the example of coal processing plant.

  19. 9 CFR 3.52 - Facilities, outdoor.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Facilities, outdoor. 3.52 Section 3.52 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ANIMAL WELFARE STANDARDS Specifications for the Humane Handling, Care, Treatment and Transportation of Rabbits...

  20. 9 CFR 3.50 - Facilities, general.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Facilities, general. 3.50 Section 3.50 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ANIMAL WELFARE STANDARDS Specifications for the Humane Handling, Care, Treatment and Transportation of Rabbits...

  1. 14 CFR 21.137 - Location of manufacturing facilities.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Location of manufacturing facilities. 21.137 Section 21.137 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT CERTIFICATION PROCEDURES FOR PRODUCTS AND PARTS Production Certificates § 21.137 Location of...

  2. 9 CFR 3.126 - Facilities, indoor.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Warmblooded Animals Other Than Dogs, Cats, Rabbits, Hamsters, Guinea Pigs, Nonhuman Primates, and Marine... 9 Animals and Animal Products 1 2011-01-01 2011-01-01 false Facilities, indoor. 3.126 Section 3.126 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE...

  3. 9 CFR 3.141 - Terminal facilities.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Warmblooded Animals Other Than Dogs, Cats, Rabbits, Hamsters, Guinea Pigs, Nonhuman Primates, and Marine... 9 Animals and Animal Products 1 2011-01-01 2011-01-01 false Terminal facilities. 3.141 Section 3.141 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE...

  4. 9 CFR 3.141 - Terminal facilities.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Warmblooded Animals Other Than Dogs, Cats, Rabbits, Hamsters, Guinea Pigs, Nonhuman Primates, and Marine... 9 Animals and Animal Products 1 2014-01-01 2014-01-01 false Terminal facilities. 3.141 Section 3.141 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE...

  5. 9 CFR 3.141 - Terminal facilities.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Warmblooded Animals Other Than Dogs, Cats, Rabbits, Hamsters, Guinea Pigs, Nonhuman Primates, and Marine... 9 Animals and Animal Products 1 2012-01-01 2012-01-01 false Terminal facilities. 3.141 Section 3.141 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE...

  6. 9 CFR 3.126 - Facilities, indoor.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Warmblooded Animals Other Than Dogs, Cats, Rabbits, Hamsters, Guinea Pigs, Nonhuman Primates, and Marine... 9 Animals and Animal Products 1 2012-01-01 2012-01-01 false Facilities, indoor. 3.126 Section 3.126 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE...

  7. 9 CFR 3.141 - Terminal facilities.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Warmblooded Animals Other Than Dogs, Cats, Rabbits, Hamsters, Guinea Pigs, Nonhuman Primates, and Marine... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Terminal facilities. 3.141 Section 3.141 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE...

  8. 9 CFR 3.125 - Facilities, general.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Warmblooded Animals Other Than Dogs, Cats, Rabbits, Hamsters, Guinea Pigs, Nonhuman Primates, and Marine... 9 Animals and Animal Products 1 2012-01-01 2012-01-01 false Facilities, general. 3.125 Section 3.125 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE...

  9. 9 CFR 3.102 - Facilities, indoor.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 9 Animals and Animal Products 1 2012-01-01 2012-01-01 false Facilities, indoor. 3.102 Section 3.102 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ANIMAL WELFARE STANDARDS Specifications for the Humane Handling, Care, Treatment, and Transportation of...

  10. 9 CFR 3.141 - Terminal facilities.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Warmblooded Animals Other Than Dogs, Cats, Rabbits, Hamsters, Guinea Pigs, Nonhuman Primates, and Marine... 9 Animals and Animal Products 1 2013-01-01 2013-01-01 false Terminal facilities. 3.141 Section 3.141 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE...

  11. 9 CFR 3.102 - Facilities, indoor.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 9 Animals and Animal Products 1 2014-01-01 2014-01-01 false Facilities, indoor. 3.102 Section 3.102 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ANIMAL WELFARE STANDARDS Specifications for the Humane Handling, Care, Treatment, and Transportation of...

  12. 9 CFR 3.126 - Facilities, indoor.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Warmblooded Animals Other Than Dogs, Cats, Rabbits, Hamsters, Guinea Pigs, Nonhuman Primates, and Marine... 9 Animals and Animal Products 1 2013-01-01 2013-01-01 false Facilities, indoor. 3.126 Section 3.126 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE...

  13. 9 CFR 3.102 - Facilities, indoor.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 9 Animals and Animal Products 1 2013-01-01 2013-01-01 false Facilities, indoor. 3.102 Section 3.102 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ANIMAL WELFARE STANDARDS Specifications for the Humane Handling, Care, Treatment, and Transportation of...

  14. 9 CFR 3.126 - Facilities, indoor.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Warmblooded Animals Other Than Dogs, Cats, Rabbits, Hamsters, Guinea Pigs, Nonhuman Primates, and Marine... 9 Animals and Animal Products 1 2014-01-01 2014-01-01 false Facilities, indoor. 3.126 Section 3.126 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE...

  15. Characterization of the animal by-product meal industry in Costa Rica: Manufacturing practices through the production chain and food safety.

    PubMed

    Leiva, A; Granados-Chinchilla, F; Redondo-Solano, M; Arrieta-González, M; Pineda-Salazar, E; Molina, A

    2018-06-01

    Animal by-product rendering establishments are still relevant industries worldwide. Animal by-product meal safety is paramount to protect feed, animals, and the rest of the food chain from unwanted contamination. As microbiological contamination may arise from inadequate processing of slaughterhouse waste and deficiencies in good manufacturing practices within the rendering facilities, we conducted an overall establishment's inspection, including the product in several parts of the process.An evaluation of the Good Manufacturing Practices (GMP) was carried out, which included the location and access (i.e., admission) to the facilities, integrated pest management programs, physical condition of the facilities (e.g., infrastructure), equipments, vehicles and transportation, as well as critical control points (i.e., particle size and temperature set at 50 mm, 133°C at atmospheric pressure for 20 min, respectively) recommended by the OIE and the European Commission. The most sensitive points according to the evaluation are physical structure of the facilities (avg 42.2%), access to the facilities (avg 48.6%), and cleaning procedures (avg 51.4%).Also, indicator microorganisms (Salmonella spp., Clostridium spp., total coliforms, E. coli, E. coli O157:H7) were used to evaluate the safety in different parts of the animal meal production process. There was a prevalence of Salmonella spp. of 12.9, 14.3, and 33.3% in Meat and Bone Meal (MBM), poultry by-products, and fish meal, respectively. However, there were no significant differences (P = 0.73) in the prevalence between the different animal meals, according to the data collected.It was also observed that renderings associated with the poultry industry (i.e., 92.0%) obtained the best ratings overall, which reflects a satisfactory development of this sector and the integration of its production system as a whole.

  16. Facility design consideration for continuous mix production of class 1.3 propellant

    NASA Technical Reports Server (NTRS)

    Williamson, K. L.; Schirk, P. G.

    1994-01-01

    In November of 1989, NASA awarded the Advanced Solid Rocket Motor (ASRM) contract to Lockheed Missiles and Space Company (LMSC) for production of advanced solid rocket motors using the continuous mix process. Aerojet ASRM division (AAD) was selected as the facility operator and RUST International Corporation provided the engineering, procurement, and construction management services. The continuous mix process mandates that the mix and cast facilities be 'close-coupled' along with the premix facilities, creating unique and challenging requirements for the facility designer. The classical approach to handling energetic materials-division into manageable quantities, segregation, and isolation-was not available due to these process requirements and quantities involved. This paper provides a description of the physical facilities, the continuous mix process, and discusses the monitoring and detection techniques used to mitigate hazards and prevent an incident.

  17. 9 CFR 93.210 - Poultry quarantine facilities.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 9 Animals and Animal Products 1 2014-01-01 2014-01-01 false Poultry quarantine facilities. 93.210... FOR MEANS OF CONVEYANCE AND SHIPPING CONTAINERS Poultry § 93.210 Poultry quarantine facilities. (a) Privately operated quarantine facilities. The importer, or his or her agent, of poultry subject to...

  18. 9 CFR 93.210 - Poultry quarantine facilities.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 9 Animals and Animal Products 1 2012-01-01 2012-01-01 false Poultry quarantine facilities. 93.210... FOR MEANS OF CONVEYANCE AND SHIPPING CONTAINERS Poultry § 93.210 Poultry quarantine facilities. (a) Privately operated quarantine facilities. The importer, or his or her agent, of poultry subject to...

  19. 9 CFR 93.210 - Poultry quarantine facilities.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 9 Animals and Animal Products 1 2011-01-01 2011-01-01 false Poultry quarantine facilities. 93.210... FOR MEANS OF CONVEYANCE AND SHIPPING CONTAINERS Poultry § 93.210 Poultry quarantine facilities. (a) Privately operated quarantine facilities. The importer, or his or her agent, of poultry subject to...

  20. 9 CFR 93.210 - Poultry quarantine facilities.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 9 Animals and Animal Products 1 2013-01-01 2013-01-01 false Poultry quarantine facilities. 93.210... FOR MEANS OF CONVEYANCE AND SHIPPING CONTAINERS Poultry § 93.210 Poultry quarantine facilities. (a) Privately operated quarantine facilities. The importer, or his or her agent, of poultry subject to...

  1. 27 CFR 22.92 - Storage facilities.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Storage facilities. 22.92... Storage facilities. (a) Storerooms or compartments shall be so constructed and secured as to prevent unauthorized access and will be equipped for locking. These storage facilities shall be of sufficient capacity...

  2. 27 CFR 22.92 - Storage facilities.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2014-04-01 2014-04-01 false Storage facilities. 22.92... Storage facilities. (a) Storerooms or compartments shall be so constructed and secured as to prevent unauthorized access and will be equipped for locking. These storage facilities shall be of sufficient capacity...

  3. 27 CFR 22.92 - Storage facilities.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2012-04-01 2012-04-01 false Storage facilities. 22.92... Storage facilities. (a) Storerooms or compartments shall be so constructed and secured as to prevent unauthorized access and will be equipped for locking. These storage facilities shall be of sufficient capacity...

  4. 27 CFR 22.92 - Storage facilities.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2011-04-01 2011-04-01 false Storage facilities. 22.92... Storage facilities. (a) Storerooms or compartments shall be so constructed and secured as to prevent unauthorized access and will be equipped for locking. These storage facilities shall be of sufficient capacity...

  5. 27 CFR 22.92 - Storage facilities.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2013-04-01 2013-04-01 false Storage facilities. 22.92... Storage facilities. (a) Storerooms or compartments shall be so constructed and secured as to prevent unauthorized access and will be equipped for locking. These storage facilities shall be of sufficient capacity...

  6. Productivity of Veterans Health Administration laboratories: a College of American Pathologists Laboratory Management Index Program (LMIP) study.

    PubMed

    Valenstein, Paul N; Wang, Edward; O'Donohue, Tom

    2003-12-01

    The Veterans Health Administration (VA) operates the largest integrated laboratory network in the United States. To assess whether the unique characteristics of VA laboratories impact efficiency of operations, we compared the productivity of VA and non-VA facilities. Financial and activity data were prospectively collected from 124 VA and 131 non-VA laboratories enrolled in the College of American Pathologists Laboratory Management Index Program (LMIP) during 2002. In addition, secular trends in 5 productivity ratios were calculated for VA and non-VA laboratories enrolled in LMIP from 1997 through 2002. Veterans Health Administration and non-VA facilities did not differ significantly in size. Inpatients accounted for a lower percentage of testing at VA facilities than non-VA facilities (21.7% vs 37.3%; P <.001). Technical staff at the median VA facility were paid more than at non-VA facilities (28.11/h dollars vs 22.60/h dollars, salaries plus benefits; P <.001), VA laboratories employed a smaller percentage of nontechnical staff (30.0% vs 41.9%; P <.001), and workers at VA laboratories worked less time per hour paid (85.5% vs 88.5%; P <.001). However, labor productivity was significantly higher at VA than at non-VA facilities (30 448 test results/total full-time equivalent (FTE)/y vs 19 260 results/total FTE; P <.001), resulting in lower labor expense per on-site test at VA sites than at non-VA sites (1.79 dollars/result vs 2.08 dollars/result; P <.001). Veterans Health Administration laboratories paid less per test for consumables (P =.003), depreciation, and maintenance than their non-VA counterparts (all P <.001), resulting in lower overall cost per on-site test result (2.64 dollars vs 3.40 dollars; P <.001). Cost per referred (sent-out) test did not differ significantly between the 2 groups. Analysis of 6-year trends showed significant increases in both VA (P <.001) and non-VA (P =.02) labor productivity (on-site tests/total FTE). Expenses at VA laboratories for labor per test, consumables per test, overall expense per test, and overall laboratory expense per discharge decreased significantly during the 6-year period (P <.001), while in non-VA facilities the corresponding ratios showed no significant change. Overall productivity of VA laboratories is superior to that of non-VA facilities enrolled in LMIP. The principal advantages enjoyed by the VA are higher-than-average labor productivity (tests/FTE) and lower-than-average consumable expenses.

  7. Throughput Optimization of Continuous Biopharmaceutical Manufacturing Facilities.

    PubMed

    Garcia, Fernando A; Vandiver, Michael W

    2017-01-01

    In order to operate profitably under different product demand scenarios, biopharmaceutical companies must design their facilities with mass output flexibility in mind. Traditional biologics manufacturing technologies pose operational challenges in this regard due to their high costs and slow equipment turnaround times, restricting the types of products and mass quantities that can be processed. Modern plant design, however, has facilitated the development of lean and efficient bioprocessing facilities through footprint reduction and adoption of disposable and continuous manufacturing technologies. These development efforts have proven to be crucial in seeking to drastically reduce the high costs typically associated with the manufacturing of recombinant proteins. In this work, mathematical modeling is used to optimize annual production schedules for a single-product commercial facility operating with a continuous upstream and discrete batch downstream platform. Utilizing cell culture duration and volumetric productivity as process variables in the model, and annual plant throughput as the optimization objective, 3-D surface plots are created to understand the effect of process and facility design on expected mass output. The model shows that once a plant has been fully debottlenecked it is capable of processing well over a metric ton of product per year. Moreover, the analysis helped to uncover a major limiting constraint on plant performance, the stability of the neutralized viral inactivated pool, which may indicate that this should be a focus of attention during future process development efforts. LAY ABSTRACT: Biopharmaceutical process modeling can be used to design and optimize manufacturing facilities and help companies achieve a predetermined set of goals. One way to perform optimization is by making the most efficient use of process equipment in order to minimize the expenditure of capital, labor and plant resources. To that end, this paper introduces a novel mathematical algorithm used to determine the most optimal equipment scheduling configuration that maximizes the mass output for a facility producing a single product. The paper also illustrates how different scheduling arrangements can have a profound impact on the availability of plant resources, and identifies limiting constraints on the plant design. In addition, simulation data is presented using visualization techniques that aid in the interpretation of the scientific concepts discussed. © PDA, Inc. 2017.

  8. Chemical processing in geothermal nuclear chimney

    DOEpatents

    Krikorian, O.H.

    1973-10-01

    A closed rubble filled nuclear chimney is provided in a subterranean geothermal formation by detonation of a nuclear explosive device therein, with reagent input and product output conduits connecting the chimney cavity with appropriate surface facilities. Such facilities will usually comprise reagent preparation, product recovery and recycle facilities. Proccsses are then conducted in the nuclear chimney which processes are facilitated by temperature, pressure, catalytic and other conditions existent or which are otherwise provided in the nuclear chimney. (auth)

  9. 40 CFR 63.5795 - How do I know if my reinforced plastic composites production facility is a new affected source or...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 12 2011-07-01 2009-07-01 true How do I know if my reinforced plastic... for Hazardous Air Pollutants: Reinforced Plastic Composites Production What This Subpart Covers § 63.5795 How do I know if my reinforced plastic composites production facility is a new affected source or...

  10. 40 CFR 63.5795 - How do I know if my reinforced plastic composites production facility is a new affected source or...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 13 2013-07-01 2012-07-01 true How do I know if my reinforced plastic... Emissions Standards for Hazardous Air Pollutants: Reinforced Plastic Composites Production What This Subpart Covers § 63.5795 How do I know if my reinforced plastic composites production facility is a new affected...

  11. 40 CFR 63.5795 - How do I know if my reinforced plastic composites production facility is a new affected source or...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 13 2014-07-01 2014-07-01 false How do I know if my reinforced plastic... Emissions Standards for Hazardous Air Pollutants: Reinforced Plastic Composites Production What This Subpart Covers § 63.5795 How do I know if my reinforced plastic composites production facility is a new affected...

  12. 40 CFR 63.5795 - How do I know if my reinforced plastic composites production facility is a new affected source or...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 13 2012-07-01 2012-07-01 false How do I know if my reinforced plastic... Emissions Standards for Hazardous Air Pollutants: Reinforced Plastic Composites Production What This Subpart Covers § 63.5795 How do I know if my reinforced plastic composites production facility is a new affected...

  13. Scientific ballooning in India Recent developments

    NASA Astrophysics Data System (ADS)

    Manchanda, R. K.

    Established in 1971, the National Balloon Facility operated by TIFR in Hyderabad, India, is a unique facility in the country, which provides a complete solution in scientific ballooning. It is also one of its kind in the world since it combines both, the in-house balloon production and a complete flight support for scientific ballooning. With a large team working through out the year to design, fabricate and launch scientific balloons, the Hyderabad Facility is a unique centre of expertise where the balloon design, research and development, the production and launch facilities are located under one roof. Our balloons are manufactured from 100% indigenous components. The mission specific balloon design, high reliability control and support instrumentation, in-house competence in tracking, telemetry, telecommand, data processing, system design and mechanics is its hallmark. In the past few years, we have executed a major programme of upgradation of different components of balloon production, telemetry and telecommand hardware and various support facilities. This paper focuses on our increased capability of balloon production of large sizes up to 780,000 m 3 using Antrix film, development of high strength balloon load tapes with the breaking strength of 182 kg, and the recent introduction of S-band telemetry and a commandable timer cut-off unit in the flight hardware. A summary of the various flights conducted in recent years will be presented along with the plans for new facilities.

  14. Decommissioning ALARA programs Cintichem decommissioning experience

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Adler, J.J.; LaGuardia, T.S.

    1995-03-01

    The Cintichem facility, originally the Union Carbide Nuclear Company (UCNC) Research Center, consisted primarily of a 5MW pool type reactor linked via a four-foot-wide by twelve-foot-deep water-filled canal to a bank of five adjacent hot cells. Shortly after going into operations in the early 1960s, the facility`s operations expanded to provide various reactor-based products and services to a multitude of research, production, medical, and education groups. From 1968 through 1972, the facility developed a process of separating isotopes from mixed fission products generated by irradiating enriched Uranium target capsules. By the late 1970s, 20 to 30 capsules were being processedmore » weekly, with about 200,000 curies being produced per week. Several isotopes such as Mo{sup 99}, I{sup 131}, and Xe{sup 133} were being extracted for medical use.« less

  15. 10 CFR 50.51 - Continuation of license.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... NUCLEAR REGULATORY COMMISSION DOMESTIC LICENSING OF PRODUCTION AND UTILIZATION FACILITIES Issuance... license will be issued for a fixed period of time to be specified in the license but in no case to exceed... expiration date to authorize ownership and possession of the production or utilization facility, until the...

  16. 10 CFR 50.51 - Continuation of license.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... NUCLEAR REGULATORY COMMISSION DOMESTIC LICENSING OF PRODUCTION AND UTILIZATION FACILITIES Issuance... license will be issued for a fixed period of time to be specified in the license but in no case to exceed... expiration date to authorize ownership and possession of the production or utilization facility, until the...

  17. 40 CFR 49.4168 - Notification and reporting requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... FEDERAL ASSISTANCE INDIAN COUNTRY: AIR QUALITY PLANNING AND MANAGEMENT Implementation Plans for Tribes-Region VIII Federal Implementation Plan for Oil and Natural Gas Well Production Facilities; Fort Berthold... you own or operate more than one oil and natural gas production facility, you may submit one report...

  18. 40 CFR 49.4168 - Notification and reporting requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... FEDERAL ASSISTANCE INDIAN COUNTRY: AIR QUALITY PLANNING AND MANAGEMENT Implementation Plans for Tribes-Region VIII Federal Implementation Plan for Oil and Natural Gas Well Production Facilities; Fort Berthold... you own or operate more than one oil and natural gas production facility, you may submit one report...

  19. Oil and Natural Gas Production Facilities National Emissions Standards for Hazardous Air Pollutants (NESHAP) Final Rule Fact Sheet

    EPA Pesticide Factsheets

    This page contains a January 2007 fact sheet for the final National Emission Standards for Hazardous Air Pollutants (NESHAP) for Oil and Natural Gas Production Facilities. This document provides a summary of the 2007 final rule.

  20. GLCF: Research

    Science.gov Websites

    Global Land Cover Facility About GLCF Research Publications Data & Products Gallery Library Services Contact Site Map Go Research The Global Land Cover Facility is a research center focusing on the GLCF in developing forest change products. Past research efforts were directed at boreal forests in

  1. MULTI-POLLUTANT CONCENTRATION MEASUREMENTS AROUND A CONCENTRATED SWINE PRODUCTION FACILITY USING OPEN-PATH FTIR SPECTROMETRY

    EPA Science Inventory

    Open-path Fourier transform infrared (OP/FTIR) spectrometry was used to measure the concentrations of ammonia, methane, and other atmospheric gasses around an integrated industrial swine production facility in eastern North Carolina. Several single-path measurements were made ove...

  2. 9 CFR 93.309 - Horse quarantine facilities; payment information.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 9 Animals and Animal Products 1 2013-01-01 2013-01-01 false Horse quarantine facilities; payment...; REQUIREMENTS FOR MEANS OF CONVEYANCE AND SHIPPING CONTAINERS Horses § 93.309 Horse quarantine facilities; payment information. (a) Privately operated quarantine facilities. The importer, or his or her agent, of...

  3. 9 CFR 93.309 - Horse quarantine facilities; payment information.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 9 Animals and Animal Products 1 2011-01-01 2011-01-01 false Horse quarantine facilities; payment...; REQUIREMENTS FOR MEANS OF CONVEYANCE AND SHIPPING CONTAINERS Horses § 93.309 Horse quarantine facilities; payment information. (a) Privately operated quarantine facilities. The importer, or his or her agent, of...

  4. 9 CFR 93.309 - Horse quarantine facilities; payment information.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Horse quarantine facilities; payment...; REQUIREMENTS FOR MEANS OF CONVEYANCE AND SHIPPING CONTAINERS Horses § 93.309 Horse quarantine facilities; payment information. (a) Privately operated quarantine facilities. The importer, or his or her agent, of...

  5. 9 CFR 93.309 - Horse quarantine facilities; payment information.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 9 Animals and Animal Products 1 2014-01-01 2014-01-01 false Horse quarantine facilities; payment...; REQUIREMENTS FOR MEANS OF CONVEYANCE AND SHIPPING CONTAINERS Horses § 93.309 Horse quarantine facilities; payment information. (a) Privately operated quarantine facilities. The importer, or his or her agent, of...

  6. 9 CFR 93.309 - Horse quarantine facilities; payment information.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 9 Animals and Animal Products 1 2012-01-01 2012-01-01 false Horse quarantine facilities; payment...; REQUIREMENTS FOR MEANS OF CONVEYANCE AND SHIPPING CONTAINERS Horses § 93.309 Horse quarantine facilities; payment information. (a) Privately operated quarantine facilities. The importer, or his or her agent, of...

  7. 49 CFR 655.73 - Access to facilities and records.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 7 2010-10-01 2010-10-01 false Access to facilities and records. 655.73 Section... OPERATIONS Administrative Requirements § 655.73 Access to facilities and records. (a) Except as required by... payment for the production of those records. (c) An employer shall permit access to all facilities...

  8. 9 CFR 11.6 - Inspection space and facility requirements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 9 Animals and Animal Products 1 2011-01-01 2011-01-01 false Inspection space and facility..., DEPARTMENT OF AGRICULTURE ANIMAL WELFARE HORSE PROTECTION REGULATIONS § 11.6 Inspection space and facility... Tennessee Walking Horses or racking horses, shall provide, without fee, sufficient space and facilities for...

  9. 9 CFR 11.6 - Inspection space and facility requirements.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 9 Animals and Animal Products 1 2012-01-01 2012-01-01 false Inspection space and facility..., DEPARTMENT OF AGRICULTURE ANIMAL WELFARE HORSE PROTECTION REGULATIONS § 11.6 Inspection space and facility... Tennessee Walking Horses or racking horses, shall provide, without fee, sufficient space and facilities for...

  10. 9 CFR 11.6 - Inspection space and facility requirements.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 9 Animals and Animal Products 1 2014-01-01 2014-01-01 false Inspection space and facility..., DEPARTMENT OF AGRICULTURE ANIMAL WELFARE HORSE PROTECTION REGULATIONS § 11.6 Inspection space and facility... Tennessee Walking Horses or racking horses, shall provide, without fee, sufficient space and facilities for...

  11. 9 CFR 93.511 - Swine quarantine facilities.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 9 Animals and Animal Products 1 2011-01-01 2011-01-01 false Swine quarantine facilities. 93.511... FOR MEANS OF CONVEYANCE AND SHIPPING CONTAINERS Swine § 93.511 Swine quarantine facilities. (a) Privately operated quarantine facilities. The importer, or his or her agent, of swine subject to quarantine...

  12. 9 CFR 93.511 - Swine quarantine facilities.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 9 Animals and Animal Products 1 2012-01-01 2012-01-01 false Swine quarantine facilities. 93.511... FOR MEANS OF CONVEYANCE AND SHIPPING CONTAINERS Swine § 93.511 Swine quarantine facilities. (a) Privately operated quarantine facilities. The importer, or his or her agent, of swine subject to quarantine...

  13. 9 CFR 93.511 - Swine quarantine facilities.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 9 Animals and Animal Products 1 2013-01-01 2013-01-01 false Swine quarantine facilities. 93.511... FOR MEANS OF CONVEYANCE AND SHIPPING CONTAINERS Swine § 93.511 Swine quarantine facilities. (a) Privately operated quarantine facilities. The importer, or his or her agent, of swine subject to quarantine...

  14. 9 CFR 93.511 - Swine quarantine facilities.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Swine quarantine facilities. 93.511... FOR MEANS OF CONVEYANCE AND SHIPPING CONTAINERS Swine § 93.511 Swine quarantine facilities. (a) Privately operated quarantine facilities. The importer, or his or her agent, of swine subject to quarantine...

  15. 9 CFR 93.511 - Swine quarantine facilities.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 9 Animals and Animal Products 1 2014-01-01 2014-01-01 false Swine quarantine facilities. 93.511... FOR MEANS OF CONVEYANCE AND SHIPPING CONTAINERS Swine § 93.511 Swine quarantine facilities. (a) Privately operated quarantine facilities. The importer, or his or her agent, of swine subject to quarantine...

  16. 27 CFR 19.19 - Discontinuance of storage facilities.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2012-04-01 2012-04-01 false Discontinuance of storage... Provisions § 19.19 Discontinuance of storage facilities. If TTB determines that a proprietor's bonded storage... spirits stored in the facility to another storage facility. The transfer will take place at such time and...

  17. 27 CFR 19.19 - Discontinuance of storage facilities.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2013-04-01 2013-04-01 false Discontinuance of storage... Provisions § 19.19 Discontinuance of storage facilities. If TTB determines that a proprietor's bonded storage... spirits stored in the facility to another storage facility. The transfer will take place at such time and...

  18. 14 CFR 21.43 - Location of manufacturing facilities.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Location of manufacturing facilities. 21.43... CERTIFICATION PROCEDURES FOR PRODUCTS AND PARTS Type Certificates § 21.43 Location of manufacturing facilities... location of the manufacturer's facilities places no undue burden on the FAA in administering applicable...

  19. 9 CFR 590.520 - Breaking room facilities.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 9 Animals and Animal Products 2 2014-01-01 2014-01-01 false Breaking room facilities. 590.520..., Processing, and Facility Requirements § 590.520 Breaking room facilities. (a) The breaking room shall have at.... (d) Ventilation shall provide for: (1) A positive flow of outside filtered air through the room; (2...

  20. 9 CFR 590.520 - Breaking room facilities.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 9 Animals and Animal Products 2 2012-01-01 2012-01-01 false Breaking room facilities. 590.520..., Processing, and Facility Requirements § 590.520 Breaking room facilities. (a) The breaking room shall have at.... (d) Ventilation shall provide for: (1) A positive flow of outside filtered air through the room; (2...

  1. 9 CFR 590.520 - Breaking room facilities.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 9 Animals and Animal Products 2 2013-01-01 2013-01-01 false Breaking room facilities. 590.520..., Processing, and Facility Requirements § 590.520 Breaking room facilities. (a) The breaking room shall have at.... (d) Ventilation shall provide for: (1) A positive flow of outside filtered air through the room; (2...

  2. Voluntary medical male circumcision scale-up in Nyanza, Kenya: evaluating technical efficiency and productivity of service delivery.

    PubMed

    Omondi Aduda, Dickens S; Ouma, Collins; Onyango, Rosebella; Onyango, Mathews; Bertrand, Jane

    2015-01-01

    Voluntary medical male circumcision (VMMC) service delivery is complex and resource-intensive. In Kenya's context there is still paucity of information on resource use vis-à-vis outputs as programs scale up. Knowledge of technical efficiency, productivity and potential sources of constraints is desirable to improve decision-making. To evaluate technical efficiency and productivity of VMMC service delivery in Nyanza in 2011/2012 using data envelopment analysis. Comparative process evaluation of facilities providing VMMC in Nyanza in 2011/2012 using output orientated data envelopment analysis. Twenty one facilities were evaluated. Only 1 of 7 variables considered (total elapsed operation time) significantly improved from 32.8 minutes (SD 8.8) in 2011 to 30 minutes (SD 6.6) in 2012 (95%CI = 0.0350-5.2488; p = 0.047). Mean scale technical efficiency significantly improved from 91% (SD 19.8) in 2011 to 99% (SD 4.0) in 2012 particularly among outreach compared to fixed service delivery facilities (CI -31.47959-4.698508; p = 0.005). Increase in mean VRS technical efficiency from 84% (SD 25.3) in 2011 and 89% (SD 25.1) in 2012 was not statistically significant. Benchmark facilities were #119 and #125 in 2011 and #103 in 2012. Malmquist Productivity Index (MPI) at fixed facilities declined by 2.5% but gained by 4.9% at outreach ones by 2012. Total factor productivity improved by 83% (p = 0.032) in 2012, largely due to progress in technological efficiency by 79% (p = 0.008). Significant improvement in scale technical efficiency among outreach facilities in 2012 was attributable to accelerated activities. However, ongoing pure technical inefficiency requires concerted attention. Technological progress was the key driver of service productivity growth in Nyanza. Incorporating service-quality dimensions and using stepwise-multiple criteria in performance evaluation enhances comprehensiveness and validity. These findings highlight site-level resource use and sources of variations in VMMC service productivity, which are important for program planning.

  3. A novel sequential vegetable production facility for life support system in space

    NASA Astrophysics Data System (ADS)

    Liu, Hui; Berkovich, Yuliy A.; Liu, Hong; Fu, Yuming; Shao, Lingzhi; Erokhin, A. N.; Wang, Minjuan

    2012-07-01

    Vegetable cultivation plays a crucial role for dietary supplements and psychosocial benefits of the crew during manned space flight. The idea of onboard vegetables cultivation was generally proposed as the first step of food regeneration in life support system of space. Here a novel sequential vegetable production facility was developed, which was able to simulate microgravity conditions and carry out modularized-cultivation of leaf-vegetables. Its growth chamber (GC) had conic form and volume of 0.12 m ^{3}. Its planting surface of 0.154 m ^{2} was comprised of six ring-shaped root modules with a fibrous ion-exchange resin substrate. Root modules were fastened to a central porous tube supplying water, and moved on along with plant growth. The total illuminated crop area of 0.567 m ^{2} was provided by a combination of both red and white light emitting diodes distributed on the GC cone internal surface. In tests with a 24-hr photoperiod, the productivity of the facility at 0.3 kW for lettuce achieved 254.3 g eatable biomass per week. Compared to lettuce from market, the quality of lettuce of the facility did not change significantly during long-term cultivation. Our results demonstrate that the facility is high efficiency in vegetable production, and basically meets the application requirements of space microgravity environment. Keywords:, vegetable; modularized-cultivation; sequential production; life support system

  4. Occurrence of pharmaceuticals in Taiwan's surface waters: impact of waste streams from hospitals and pharmaceutical production facilities.

    PubMed

    Lin, Angela Yu-Chen; Tsai, Yu-Ting

    2009-06-01

    We investigated the occurrence and distribution of pharmaceuticals (including antibiotics, estrogens, non-steroidal anti-inflammatory drugs (NSAIDs), beta-blockers, and lipid regulators) in three rivers and in the waste streams of six hospitals and four pharmaceutical production facilities in Taiwan. The most frequently detected pharmaceuticals were acetaminophen, erythromycin-H(2)O, sulfamethoxazole, and gemfibrozil. NSAIDs were the next most-often detected compounds, with a detection frequency >60%. The other analytes were not detected or were seen in only a few samples at trace concentrations. The present study demonstrates a significant discharge of human medications from hospital and drug production facilities into surface waters in the Taipei district. The high concentrations of pharmaceuticals found in the Sindian and Dahan rivers demonstrate the alarming degree to which they have been impacted by urban drainage (waste effluents from hospitals, households, and pharmaceutical production facilities). The ubiquitous occurrence at extremely high concentrations of acetaminophen and erythromycin-H(2)O in both rivers (up to 15.7 and 75.5 microg/L) and in wastewater from hospitals and pharmaceutical production facilities (up to 417.5 and 7.84 microg/L) was unique. This finding, in combination with acetaminophen's status as the drug most often prescribed by Taiwan's dominant clinical institute, suggests the potential use of acetaminophen as a molecular indicator of contamination of Taiwan's aqueous environments with untreated urban drainage.

  5. Design Process Overview

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Halkjaer-Knudsen, Vibeke

    2014-11-01

    For the purposes of this paper, a Biocontainment facility is a laboratory, production facility, or similar building that handles contagious biological materials in a safe and responsible manner. This specialized facility, also called a containment facility or a high containment facility reduces the potential for biological agents to be released into the environment, provides a safe work environment for the employees, and supports good laboratory practices.

  6. Garden Banks 388 subsea drilling/production template: Project management of a fast-track project

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ledbetter, W.R.

    1995-10-01

    Enserch Exploration`s Garden Banks 388 development is a production scheme based around a floating drilling and production facility and subsea drilling/production template. The Floating Production Facility (FPF) is a converted semisubmersible drilling rig which will drill and product through a 24-well slot template. This development is located in Block 388 of the Garden Banks area in the Gulf of Mexico approximately 200 miles southwest of New Orleans. Louisiana. This production system is being installed in an area of known oil and gas reserves and will produce to a shallow water platform 54 miles away at Ewing Bank 315. The FPFmore » will be permanently moored on the surface above the template. The subsea template has been installed in 2,190 feet of water and will produce through a 2,000 foot free-standing production riser system to the FPF. The produced fluids are partially separated on the FPF before oil and gas are pumped through the template to export gathering lines which are connected to the shallow water facility.« less

  7. An integrated prediction and optimization model of biogas production system at a wastewater treatment facility.

    PubMed

    Akbaş, Halil; Bilgen, Bilge; Turhan, Aykut Melih

    2015-11-01

    This study proposes an integrated prediction and optimization model by using multi-layer perceptron neural network and particle swarm optimization techniques. Three different objective functions are formulated. The first one is the maximization of methane percentage with single output. The second one is the maximization of biogas production with single output. The last one is the maximization of biogas quality and biogas production with two outputs. Methane percentage, carbon dioxide percentage, and other contents' percentage are used as the biogas quality criteria. Based on the formulated models and data from a wastewater treatment facility, optimal values of input variables and their corresponding maximum output values are found out for each model. It is expected that the application of the integrated prediction and optimization models increases the biogas production and biogas quality, and contributes to the quantity of electricity production at the wastewater treatment facility. Copyright © 2015 Elsevier Ltd. All rights reserved.

  8. 75 FR 71072 - Initiation and Preliminary Results of Antidumping Duty Changed Circumstances Review: Certain...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-22

    ... factors including, but not limited to: (1) Management; (2) production facilities; (3) supplier relationships; and (4) customer base. See Brass Sheet and Strip from Canada: Final Results of Antidumping Duty... y Placa resulted in little or no change in management, production facilities, supplier relationships...

  9. 9 CFR 166.5 - Licensed garbage-treatment facility standards.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 9 Animals and Animal Products 1 2011-01-01 2011-01-01 false Licensed garbage-treatment facility standards. 166.5 Section 166.5 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE... where insects and rodents may breed is prohibited. (b) Equipment used for handling untreated garbage...

  10. 75 FR 34757 - Information Collection Sent to the Office of Management and Budget (OMB) for Approval; OMB...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-18

    ...-0137; Applications for Single Use Permits and Registration of Production Facilities (CITES) AGENCY...-0137. Title: Applications for Single Use Permits and Registration of Production Facilities (CITES), 50... import or export of CITES-listed species, the Management Authority and Scientific Authority must make...

  11. Spatio-temporal distribution of stored-product inects around food processing and storage facilities

    USDA-ARS?s Scientific Manuscript database

    Grain storage and processing facilities consist of a landscape of indoor and outdoor habitats that can potentially support stored-product insect pests, and understanding patterns of species diversity and spatial distribution in the landscape surrounding structures can provide insight into how the ou...

  12. 9 CFR 590.560 - Health and hygiene of personnel.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Health and hygiene of personnel. 590.560 Section 590.560 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF..., Processing, and Facility Requirements § 590.560 Health and hygiene of personnel. (a) Personnel facilities...

  13. 9 CFR 590.560 - Health and hygiene of personnel.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 9 Animals and Animal Products 2 2011-01-01 2011-01-01 false Health and hygiene of personnel. 590.560 Section 590.560 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF..., Processing, and Facility Requirements § 590.560 Health and hygiene of personnel. (a) Personnel facilities...

  14. 18 CFR 292.203 - General requirements for qualification.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ..., pursuant to § 292.207(b)(1), that has been granted. (c) Hydroelectric small power production facilities located at a new dam or diversion. (1) A hydroelectric small power production facility that impounds or... 18 Conservation of Power and Water Resources 1 2012-04-01 2012-04-01 false General requirements...

  15. 18 CFR 292.203 - General requirements for qualification.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ..., pursuant to § 292.207(b)(1), that has been granted. (c) Hydroelectric small power production facilities located at a new dam or diversion. (1) A hydroelectric small power production facility that impounds or... 18 Conservation of Power and Water Resources 1 2011-04-01 2011-04-01 false General requirements...

  16. 18 CFR 292.203 - General requirements for qualification.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ..., pursuant to § 292.207(b)(1), that has been granted. (c) Hydroelectric small power production facilities located at a new dam or diversion. (1) A hydroelectric small power production facility that impounds or... 18 Conservation of Power and Water Resources 1 2014-04-01 2014-04-01 false General requirements...

  17. 18 CFR 292.203 - General requirements for qualification.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ..., pursuant to § 292.207(b)(1), that has been granted. (c) Hydroelectric small power production facilities located at a new dam or diversion. (1) A hydroelectric small power production facility that impounds or... 18 Conservation of Power and Water Resources 1 2013-04-01 2013-04-01 false General requirements...

  18. 78 FR 68055 - Information Collection Request Submitted to OMB for Review and Approval; Comment Request; NESHAP...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-13

    ... Polyurethane Foam Production and Fabrication, Lead Acid Battery Manufacturing, and Wood Preserving (Renewal... Polyurethane Foam Production and Fabrication, Lead Acid Battery Manufacturing, and Wood Preserving (40 CFR Part... battery manufacturing facilities, and 393 existing wood preserving facilities. The total annual responses...

  19. 9 CFR 85.13 - Cleaning and disinfecting livestock markets and other facilities.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 9 Animals and Animal Products 1 2014-01-01 2014-01-01 false Cleaning and disinfecting livestock markets and other facilities. 85.13 Section 85.13 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE INTERSTATE TRANSPORTATION OF ANIMALS (INCLUDING POULTRY) AND...

  20. 9 CFR 2.102 - Holding facility.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 9 Animals and Animal Products 1 2013-01-01 2013-01-01 false Holding facility. 2.102 Section 2.102 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ANIMAL... another person hold animals for the required period provided for in paragraph (a) of § 2.101: Provided...

  1. 9 CFR 590.520 - Breaking room facilities.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 9 Animals and Animal Products 2 2011-01-01 2011-01-01 false Breaking room facilities. 590.520 Section 590.520 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE... least 30 foot-candles of light on all working surfaces except that light intensity shall be at least 50...

  2. 9 CFR 85.13 - Cleaning and disinfecting livestock markets and other facilities.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Cleaning and disinfecting livestock markets and other facilities. 85.13 Section 85.13 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE INTERSTATE TRANSPORTATION OF ANIMALS (INCLUDING POULTRY) AND...

  3. 9 CFR 85.13 - Cleaning and disinfecting livestock markets and other facilities.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 9 Animals and Animal Products 1 2012-01-01 2012-01-01 false Cleaning and disinfecting livestock markets and other facilities. 85.13 Section 85.13 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE INTERSTATE TRANSPORTATION OF ANIMALS (INCLUDING POULTRY) AND...

  4. 9 CFR 85.13 - Cleaning and disinfecting livestock markets and other facilities.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 9 Animals and Animal Products 1 2011-01-01 2011-01-01 false Cleaning and disinfecting livestock markets and other facilities. 85.13 Section 85.13 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE INTERSTATE TRANSPORTATION OF ANIMALS (INCLUDING POULTRY) AND...

  5. 9 CFR 85.13 - Cleaning and disinfecting livestock markets and other facilities.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 9 Animals and Animal Products 1 2013-01-01 2013-01-01 false Cleaning and disinfecting livestock markets and other facilities. 85.13 Section 85.13 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE INTERSTATE TRANSPORTATION OF ANIMALS (INCLUDING POULTRY) AND...

  6. Grasse River Superfund Site, Massena, NY

    EPA Pesticide Factsheets

    Alcoa, Inc. has owned and operated an aluminum product manufacturing facility called Alcoa West facility in the Town of Massena, New York, since 1903. In connection with its past operations at the facility, Alcoa released hazardous substances, including

  7. 21 CFR 212.100 - What do I do if I receive a complaint about a PET drug product produced at my facility?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 4 2012-04-01 2012-04-01 false What do I do if I receive a complaint about a PET... complaint about a PET drug product produced at my facility? (a) Written complaint procedures. You must... quality or purity of, or possible adverse reactions to, a PET drug product. (b) Complaint review. The...

  8. 21 CFR 212.100 - What do I do if I receive a complaint about a PET drug product produced at my facility?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 4 2011-04-01 2011-04-01 false What do I do if I receive a complaint about a PET... complaint about a PET drug product produced at my facility? (a) Written complaint procedures. You must... quality or purity of, or possible adverse reactions to, a PET drug product. (b) Complaint review. The...

  9. 21 CFR 212.100 - What do I do if I receive a complaint about a PET drug product produced at my facility?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 4 2013-04-01 2013-04-01 false What do I do if I receive a complaint about a PET... complaint about a PET drug product produced at my facility? (a) Written complaint procedures. You must... quality or purity of, or possible adverse reactions to, a PET drug product. (b) Complaint review. The...

  10. 21 CFR 212.100 - What do I do if I receive a complaint about a PET drug product produced at my facility?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 4 2014-04-01 2014-04-01 false What do I do if I receive a complaint about a PET... complaint about a PET drug product produced at my facility? (a) Written complaint procedures. You must... quality or purity of, or possible adverse reactions to, a PET drug product. (b) Complaint review. The...

  11. 76 FR 50663 - Revisions to Form, Procedures and Criteria for Certification of Qualifying Facility Status for a...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-16

    ... facilities. List of Subjects in 18 CFR Part 292 Electric power, Electric power plants, Electric utilities... to Form, Procedures and Criteria for Certification of Qualifying Facility Status for a Small Power... small power production or cogeneration facility. DATES: August 16, 2011. FOR FURTHER INFORMATION CONTACT...

  12. 9 CFR 3.79 - Mobile or traveling housing facilities.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... barriers. There must be a barrier between a mobile or traveling housing facility and the public at any time... 9 Animals and Animal Products 1 2012-01-01 2012-01-01 false Mobile or traveling housing facilities... Transportation of Nonhuman Primates 2 Facilities and Operating Standards § 3.79 Mobile or traveling housing...

  13. 9 CFR 3.79 - Mobile or traveling housing facilities.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... barriers. There must be a barrier between a mobile or traveling housing facility and the public at any time... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Mobile or traveling housing facilities... Transportation of Nonhuman Primates 2 Facilities and Operating Standards § 3.79 Mobile or traveling housing...

  14. 9 CFR 590.506 - Candling and transfer-room facilities and equipment.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 9 Animals and Animal Products 2 2011-01-01 2011-01-01 false Candling and transfer-room facilities... INSPECTION ACT) Sanitary, Processing, and Facility Requirements § 590.506 Candling and transfer-room facilities and equipment. (a) The room shall be so constructed that it can be adequately darkened to assure...

  15. 9 CFR 590.506 - Candling and transfer-room facilities and equipment.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 9 Animals and Animal Products 2 2012-01-01 2012-01-01 false Candling and transfer-room facilities... INSPECTION ACT) Sanitary, Processing, and Facility Requirements § 590.506 Candling and transfer-room facilities and equipment. (a) The room shall be so constructed that it can be adequately darkened to assure...

  16. 9 CFR 590.506 - Candling and transfer-room facilities and equipment.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 9 Animals and Animal Products 2 2013-01-01 2013-01-01 false Candling and transfer-room facilities... INSPECTION ACT) Sanitary, Processing, and Facility Requirements § 590.506 Candling and transfer-room facilities and equipment. (a) The room shall be so constructed that it can be adequately darkened to assure...

  17. 9 CFR 590.506 - Candling and transfer-room facilities and equipment.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 9 Animals and Animal Products 2 2014-01-01 2014-01-01 false Candling and transfer-room facilities... INSPECTION ACT) Sanitary, Processing, and Facility Requirements § 590.506 Candling and transfer-room facilities and equipment. (a) The room shall be so constructed that it can be adequately darkened to assure...

  18. Making contact: rooting out the potential for exposure of commercial production swine facilities to feral swine in North Carolina.

    PubMed

    Engeman, Richard; Betsill, Carl; Ray, Tom

    2011-03-01

    Despite North Carolina's long history with feral swine, populations were low or absent in eastern counties until the 1990s. Feral swine populations have since grown in these counties which also contain a high density of commercial production swine (CPS) facilities. Sixteen of the highest swine producing U.S. counties also populated with feral swine are in North Carolina. Disconcertingly, since 2009, positive tests for exposure to swine brucellosis or pseudorabies virus have been found for feral swine. We surveyed 120 CSP facilities across four eastern counties to document the level and perception of feral swine activity around CSP facilities and to identify disease transmission potential to commercial stock. Nearly all facility operators (97%) recognized feral swine were in their counties. Far fewer said they had feral swine activity nearby (18%). Our inspections found higher presence than perceived with feral swine sign at 19% of facilities where operators said they had never observed feral swine or their sign. Nearly 90% expressed concern about feral to domestic disease transmission, yet only two facilities had grain bins or feeders fenced against wildlife access. Due to increasing feral swine populations, recent evidence of disease in feral populations, the importance of swine production to North Carolina's economy and the national pork industry, and potential for feral-domestic contact, we believe feral swine pose an increasing disease transmission threat warranting a stringent look at biosecurity and feral swine management at North Carolina CPS facilities.

  19. 40 CFR 60.730 - Applicability and designation of affected facility.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... facility. For the brick and related clay products industry, only the calcining and drying of raw materials prior to firing of the brick are covered. (b) An affected facility that is subject to the provisions of...

  20. 40 CFR 60.730 - Applicability and designation of affected facility.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... facility. For the brick and related clay products industry, only the calcining and drying of raw materials prior to firing of the brick are covered. (b) An affected facility that is subject to the provisions of...

  1. 40 CFR 60.730 - Applicability and designation of affected facility.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... facility. For the brick and related clay products industry, only the calcining and drying of raw materials prior to firing of the brick are covered. (b) An affected facility that is subject to the provisions of...

  2. 40 CFR 60.730 - Applicability and designation of affected facility.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... facility. For the brick and related clay products industry, only the calcining and drying of raw materials prior to firing of the brick are covered. (b) An affected facility that is subject to the provisions of...

  3. 40 CFR 60.730 - Applicability and designation of affected facility.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... facility. For the brick and related clay products industry, only the calcining and drying of raw materials prior to firing of the brick are covered. (b) An affected facility that is subject to the provisions of...

  4. Analyzing industrial energy use through ordinary least squares regression models

    NASA Astrophysics Data System (ADS)

    Golden, Allyson Katherine

    Extensive research has been performed using regression analysis and calibrated simulations to create baseline energy consumption models for residential buildings and commercial institutions. However, few attempts have been made to discuss the applicability of these methodologies to establish baseline energy consumption models for industrial manufacturing facilities. In the few studies of industrial facilities, the presented linear change-point and degree-day regression analyses illustrate ideal cases. It follows that there is a need in the established literature to discuss the methodologies and to determine their applicability for establishing baseline energy consumption models of industrial manufacturing facilities. The thesis determines the effectiveness of simple inverse linear statistical regression models when establishing baseline energy consumption models for industrial manufacturing facilities. Ordinary least squares change-point and degree-day regression methods are used to create baseline energy consumption models for nine different case studies of industrial manufacturing facilities located in the southeastern United States. The influence of ambient dry-bulb temperature and production on total facility energy consumption is observed. The energy consumption behavior of industrial manufacturing facilities is only sometimes sufficiently explained by temperature, production, or a combination of the two variables. This thesis also provides methods for generating baseline energy models that are straightforward and accessible to anyone in the industrial manufacturing community. The methods outlined in this thesis may be easily replicated by anyone that possesses basic spreadsheet software and general knowledge of the relationship between energy consumption and weather, production, or other influential variables. With the help of simple inverse linear regression models, industrial manufacturing facilities may better understand their energy consumption and production behavior, and identify opportunities for energy and cost savings. This thesis study also utilizes change-point and degree-day baseline energy models to disaggregate facility annual energy consumption into separate industrial end-user categories. The baseline energy model provides a suitable and economical alternative to sub-metering individual manufacturing equipment. One case study describes the conjoined use of baseline energy models and facility information gathered during a one-day onsite visit to perform an end-point energy analysis of an injection molding facility conducted by the Alabama Industrial Assessment Center. Applying baseline regression model results to the end-point energy analysis allowed the AIAC to better approximate the annual energy consumption of the facility's HVAC system.

  5. Assessment of Component-level Emission Measurements ...

    EPA Pesticide Factsheets

    Oil and natural gas (ONG) production facilities have the potential to emit a substantial amount of greenhouse gasses, hydrocarbons and hazardous air pollutants into the atmosphere. These emissions come from a wide variety of sources including engine exhaust, combustor gases, atmospheric venting from uncontrolled tanks and leaks. Engine exhaust, combustor gases and atmospheric tank venting are included in the initial estimation of a production facilities cumulative emissions. However, there is a large amount of uncertainty associated with magnitude and composition of leaks at these facilities. In order to understand the environmental impacts of these emissions we must first be able characterize the emission flow rate and chemical composition of these leaks/venting. A number of recent publications regarding emission flow rate measurements of components at ONG production facilities have brought into question the validity of such measurements and the sampling methodology. An accurate methodology for quantifying hydrocarbon leaks/venting is needed to support both emission inventories and environmental compliance. This interim report will summarize recent results from a small leak survey completed at ONG production facilities in Utah to characterize their flow rate and chemical composition using a suite of instruments using a high volume sampler (Bacharach Hi Flow Sampler; Bacharach, Inc.), as well as infrared (IR) cameras, a photoionization detector (PID), a fl

  6. Commercial-scale biotherapeutics manufacturing facility for plant-made pharmaceuticals.

    PubMed

    Holtz, Barry R; Berquist, Brian R; Bennett, Lindsay D; Kommineni, Vally J M; Munigunti, Ranjith K; White, Earl L; Wilkerson, Don C; Wong, Kah-Yat I; Ly, Lan H; Marcel, Sylvain

    2015-10-01

    Rapid, large-scale manufacture of medical countermeasures can be uniquely met by the plant-made-pharmaceutical platform technology. As a participant in the Defense Advanced Research Projects Agency (DARPA) Blue Angel project, the Caliber Biotherapeutics facility was designed, constructed, commissioned and released a therapeutic target (H1N1 influenza subunit vaccine) in <18 months from groundbreaking. As of 2015, this facility was one of the world's largest plant-based manufacturing facilities, with the capacity to process over 3500 kg of plant biomass per week in an automated multilevel growing environment using proprietary LED lighting. The facility can commission additional plant grow rooms that are already built to double this capacity. In addition to the commercial-scale manufacturing facility, a pilot production facility was designed based on the large-scale manufacturing specifications as a way to integrate product development and technology transfer. The primary research, development and manufacturing system employs vacuum-infiltrated Nicotiana benthamiana plants grown in a fully contained, hydroponic system for transient expression of recombinant proteins. This expression platform has been linked to a downstream process system, analytical characterization, and assessment of biological activity. This integrated approach has demonstrated rapid, high-quality production of therapeutic monoclonal antibody targets, including a panel of rituximab biosimilar/biobetter molecules and antiviral antibodies against influenza and dengue fever. © 2015 Society for Experimental Biology, Association of Applied Biologists and John Wiley & Sons Ltd.

  7. 43 CFR 3277.11 - What records must I keep available for inspection?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... operation of your utilization facility, royalty and production meters, and safety training available for BLM inspection for a period of 6 years following the time the records and information are created. (b) This... needs them to determine: (1) Resource production to a utilization facility; or (2) The allocation of...

  8. 7 CFR 4288.137 - Succession and loss of control of advanced biofuel facilities and production.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 15 2012-01-01 2012-01-01 false Succession and loss of control of advanced biofuel... PROGRAMS Advanced Biofuel Payment Program General Provisions § 4288.137 Succession and loss of control of advanced biofuel facilities and production. (a) Contract succession. An entity who becomes the eligible...

  9. 7 CFR 4288.137 - Succession and loss of control of advanced biofuel facilities and production.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 15 2014-01-01 2014-01-01 false Succession and loss of control of advanced biofuel... PROGRAMS Advanced Biofuel Payment Program General Provisions Payment Provisions § 4288.137 Succession and loss of control of advanced biofuel facilities and production. (a) Contract succession. An entity who...

  10. 7 CFR 4288.137 - Succession and loss of control of advanced biofuel facilities and production.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 15 2013-01-01 2013-01-01 false Succession and loss of control of advanced biofuel... PROGRAMS Advanced Biofuel Payment Program General Provisions § 4288.137 Succession and loss of control of advanced biofuel facilities and production. (a) Contract succession. An entity who becomes the eligible...

  11. 15 CFR 712.3 - Initial declaration requirements for declared facilities which are engaged in the production of...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Foreign Trade (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE CHEMICAL WEAPONS CONVENTION REGULATIONS ACTIVITIES INVOLVING SCHEDULE 1 CHEMICALS § 712.3 Initial declaration requirements for... declared facilities which are engaged in the production of Schedule 1 chemicals for purposes not prohibited...

  12. Identification of 'Candidatus Piscichlamydia salmonis' in Arctic charr Salvelinus alpinus during a survey of charr production facilities in North America

    USDA-ARS?s Scientific Manuscript database

    Artic charr Salvelinus alpinus production facilities, nonproduction water sources and effluents in the United States and Canada were sampled to determine if chlamydiae associated with epitheliocystis were present in water and were associated with inclusions of epitheliocystis in gill tissue. Gills f...

  13. 27 CFR 19.19 - Discontinuance of storage facilities.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... due on the spirits and then to the cost and expense of the sale and removal, and the remaining balance... 27 Alcohol, Tobacco Products and Firearms 1 2011-04-01 2011-04-01 false Discontinuance of storage facilities. 19.19 Section 19.19 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE...

  14. 12 CFR 7.5002 - Furnishing of products and services by electronic means and facilities.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 1 2011-01-01 2011-01-01 false Furnishing of products and services by electronic means and facilities. 7.5002 Section 7.5002 Banks and Banking COMPTROLLER OF THE CURRENCY, DEPARTMENT OF THE TREASURY BANK ACTIVITIES AND OPERATIONS Electronic Activities § 7.5002 Furnishing of...

  15. 76 FR 29260 - Incidental Take Permit; San Bernardino County, CA; Proposed Habitat Conservation Plan, Draft...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-20

    ... related to operations and maintenance of storage and distribution facilities for petroleum products within the Colton and Colton North Terminals, and with habitat restoration and management on a proposed on... maintenance of storage and distribution facilities for petroleum products on approximately 20 acres (ac) (8...

  16. 75 FR 63093 - Oil Pollution Prevention; Spill Prevention, Control, and Countermeasure (SPCC) Rule-Compliance...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-14

    ... the compliance date by which facilities must address milk and milk product containers, associated... facility must comply with the SPCC requirements for these milk and milk product containers is delayed one... containers, associated piping and appurtenances, or as specified by a rule that otherwise establishes a...

  17. 40 CFR 63.11164 - What General Provisions apply to primary zinc production facilities?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 15 2013-07-01 2013-07-01 false What General Provisions apply to primary zinc production facilities? 63.11164 Section 63.11164 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS FOR SOURCE CATEGORIES (CONTINUED)...

  18. 40 CFR 63.11164 - What General Provisions apply to primary zinc production facilities?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 15 2012-07-01 2012-07-01 false What General Provisions apply to primary zinc production facilities? 63.11164 Section 63.11164 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS FOR SOURCE CATEGORIES (CONTINUED)...

  19. 40 CFR 63.11164 - What General Provisions apply to primary zinc production facilities?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 15 2014-07-01 2014-07-01 false What General Provisions apply to primary zinc production facilities? 63.11164 Section 63.11164 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS FOR SOURCE CATEGORIES (CONTINUED)...

  20. Synthetic fiber production facilities: Background information for proposed standards

    NASA Astrophysics Data System (ADS)

    Goodwin, D. R.

    1982-10-01

    Standards of performance to control emissions of volatile organic compounds (VOC) from new, modified, and reconstructed synthetic fiber production facilities are being proposed under section III of the Clean Air Act. This document contains information on the background and authority, regulatory alternatives considered, and environmental and economic impacts of the regulatory alternatives.

  1. 15 CFR 712.3 - Initial declaration requirements for declared facilities which are engaged in the production of...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Foreign Trade (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE CHEMICAL WEAPONS CONVENTION REGULATIONS ACTIVITIES INVOLVING SCHEDULE 1 CHEMICALS § 712.3 Initial declaration requirements for... declared facilities which are engaged in the production of Schedule 1 chemicals for purposes not prohibited...

  2. 75 FR 71733 - Requirements for Measurement Facilities Used for the Royalty Valuation of Processed Natural Gas

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-24

    ... measurement of inlet production, residue gas, fuel gas, flare gas, condensate, natural gas liquids, or any... governing gas and liquid hydrocarbon production measurement. We have recently completed the first phase of... Requirements for Measurement Facilities Used for the Royalty Valuation of Processed Natural Gas AGENCY: Bureau...

  3. 9 CFR 108.9 - Dressing rooms and other facilities.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 9 Animals and Animal Products 1 2011-01-01 2011-01-01 false Dressing rooms and other facilities. 108.9 Section 108.9 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT... running water, soap, towels, and the like. They shall be in sufficient number, ample in size, conveniently...

  4. 21 CFR 212.100 - What do I do if I receive a complaint about a PET drug product produced at my facility?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 4 2010-04-01 2010-04-01 false What do I do if I receive a complaint about a PET... if I receive a complaint about a PET drug product produced at my facility? (a) Written complaint... concerning the quality or purity of, or possible adverse reactions to, a PET drug product. (b) Complaint...

  5. Corps of Engineers’ Acquisition of Fish Hatchery Proves Costly.

    DTIC Science & Technology

    1981-09-18

    location, size, esti- mated cost, design , and construction timetables for facilities needed to meet the steelhead production requirements. To limit...hatchery "* * * is not recognized to be one of the more efficient and productive facilities in Idaho due to obvious con- straints in design , construction...agency’s decision to supply the product or service it- self because it would cost less must be supported by a comparativ , cost analysis. According to Corps

  6. Topical otic drugs in a multi-purpose manufacturing facility: a guide on determination and application of permitted daily exposure (PDE).

    PubMed

    Wiesner, Lisa; Prause, Maarten; Lovsin Barle, Ester

    2018-03-01

    Due to newly introduced EU GMP (Good Manufacturing Practice) guideline for Medicinal Products for Human and Veterinary use, product specific permitted daily exposure (PDE) for toxicological evaluation in multi-purpose facilities are required within a documented process for risk assessment. European Medicines Agency (EMA) guidance on setting PDE limits so far focused on systemic administration routes such as intravenous (IV), oral or inhalation. This article provides guidance on setting PDE values for risk management purposes in multi-purpose facilities for active pharmaceutical ingredients (APIs) applied as topical otic drugs to the outer ear canal. The therewith determined PDE otic, is used for the calculation of maximum safe carry-over (MSC) in manufacturing scenarios where a topical otic product is manufactured followed by another topical otic product.

  7. A High-Speed Continuous Recording High Flow Gas Sampler for Measuring Methane Emissions from Pneumatic Devices at Oil and Natural Gas Production Facilities

    NASA Astrophysics Data System (ADS)

    Ferrara, T.; Howard, T. M.

    2016-12-01

    Studies attempting to reconcile facility level emission estimates of sources at oil and gas facilities with basin wide methane flux measurements have had limited success. Pneumatic devices are commonly used at oil and gas production facilities for process control or liquid pumping. These devices are powered by pressurized natural gas from the well, so they are known methane sources at these sites. Pneumatic devices are estimated to contribute 14% to 25% of the total greenhouse gas emissions (GHG) from production facilities. Measurements of pneumatic devices have shown that malfunctioning or poorly maintained control systems may be emitting significantly more methane than currently estimated. Emission inventories for these facilities use emission factors from EPA that are based on pneumatic device measurements made in the early 1990's. Recent studies of methane emissions from production facilities have attempted to measure emissions from pneumatic devices by several different methods. These methods have had limitations including alteration of the system being measured, the inability to distinguish between leaks and venting during normal operation, or insufficient response time to account of the time based emission events. We have developed a high speed recording high flow sampler that is capable of measuring the transient emissions from pneumatic devices. This sampler is based on the well-established high flow measurement technique used in oil and gas for quantifying component leak rates. In this paper we present the results of extensive laboratory controlled release testing. Additionally, test data from several field studies where this sampler has been used to measure pneumatic device emissions will be presented.

  8. 41 CFR 102-74.315 - What is the smoking policy for interior space in Federal facilities?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false What is the smoking... REGULATION REAL PROPERTY 74-FACILITY MANAGEMENT Facility Management Smoking § 102-74.315 What is the smoking... and members of the public visiting or using Federal facilities. The smoking of tobacco products is...

  9. 41 CFR 102-74.315 - What is the smoking policy for interior space in Federal facilities?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 41 Public Contracts and Property Management 3 2013-07-01 2013-07-01 false What is the smoking... REGULATION REAL PROPERTY 74-FACILITY MANAGEMENT Facility Management Smoking § 102-74.315 What is the smoking... and members of the public visiting or using Federal facilities. The smoking of tobacco products is...

  10. 41 CFR 102-74.315 - What is the smoking policy for interior space in Federal facilities?

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 41 Public Contracts and Property Management 3 2012-01-01 2012-01-01 false What is the smoking... REGULATION REAL PROPERTY 74-FACILITY MANAGEMENT Facility Management Smoking § 102-74.315 What is the smoking... and members of the public visiting or using Federal facilities. The smoking of tobacco products is...

  11. 41 CFR 102-74.315 - What is the smoking policy for interior space in Federal facilities?

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 41 Public Contracts and Property Management 3 2014-01-01 2014-01-01 false What is the smoking... REGULATION REAL PROPERTY 74-FACILITY MANAGEMENT Facility Management Smoking § 102-74.315 What is the smoking... and members of the public visiting or using Federal facilities. The smoking of tobacco products is...

  12. 41 CFR 102-74.315 - What is the smoking policy for interior space in Federal facilities?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 41 Public Contracts and Property Management 3 2011-01-01 2011-01-01 false What is the smoking... REGULATION REAL PROPERTY 74-FACILITY MANAGEMENT Facility Management Smoking § 102-74.315 What is the smoking... and members of the public visiting or using Federal facilities. The smoking of tobacco products is...

  13. AMS data production facilities at science operations center at CERN

    NASA Astrophysics Data System (ADS)

    Choutko, V.; Egorov, A.; Eline, A.; Shan, B.

    2017-10-01

    The Alpha Magnetic Spectrometer (AMS) is a high energy physics experiment on the board of the International Space Station (ISS). This paper presents the hardware and software facilities of Science Operation Center (SOC) at CERN. Data Production is built around production server - a scalable distributed service which links together a set of different programming modules for science data transformation and reconstruction. The server has the capacity to manage 1000 paralleled job producers, i.e. up to 32K logical processors. Monitoring and management tool with Production GUI is also described.

  14. Keratin-based products for effective wound care management in superficial and partial thickness burns injuries.

    PubMed

    Loan, Fiona; Cassidy, Sharon; Marsh, Clive; Simcock, Jeremy

    2016-05-01

    This n=40 cohort study on superficial and partial thickness burns compares novel keratin-based products with the standard products used at our facility. The keratin products are found to facilitate healing with minimal scarring, be well tolerated with minimal pain and itch, be easy to use for the health professional and be cost effective for the health care provider. For these reasons they are being adopted into use at our facility. Copyright © 2015 Elsevier Ltd and ISBI. All rights reserved.

  15. 49 CFR 33.20 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... warehousing, ports, services, equipment and facilities, such as transportation carrier shop and repair.... Health resources means drugs, biological products, medical devices, materials, facilities, health...

  16. 49 CFR 33.20 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... warehousing, ports, services, equipment and facilities, such as transportation carrier shop and repair.... Health resources means drugs, biological products, medical devices, materials, facilities, health...

  17. 49 CFR 33.20 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... warehousing, ports, services, equipment and facilities, such as transportation carrier shop and repair.... Health resources means drugs, biological products, medical devices, materials, facilities, health...

  18. U.S. Air Force Environmental Assessment, Add To and Alter Type III Hydrant Fueling System, Tinker Air Force Base, Oklahoma

    DTIC Science & Technology

    2011-12-01

    burning of fossil fuels (e.g., oil , natural gas , coal), solid waste decay, and trees and wood products and also as a result of chemical reactions...to negative GHG effects. Methane. CH4 is a GHG that is emitted during the production and transport of coal, natural gas , and oil . Methane...the pump station (Facility 486); Control Room (Facility 487); and the oil -water separator (Facility 488). • Construction of a new Type III pump house

  19. Characterization of the animal by-product meal industry in Costa Rica: Manufacturing practices through the production chain and food safety

    PubMed Central

    Leiva, A; Granados-Chinchilla, F; Redondo-Solano, M; Arrieta-González, M; Pineda-Salazar, E; Molina, A

    2018-01-01

    ABSTRACT Animal by-product rendering establishments are still relevant industries worldwide. Animal by-product meal safety is paramount to protect feed, animals, and the rest of the food chain from unwanted contamination. As microbiological contamination may arise from inadequate processing of slaughterhouse waste and deficiencies in good manufacturing practices within the rendering facilities, we conducted an overall establishment's inspection, including the product in several parts of the process. An evaluation of the Good Manufacturing Practices (GMP) was carried out, which included the location and access (i.e., admission) to the facilities, integrated pest management programs, physical condition of the facilities (e.g., infrastructure), equipments, vehicles and transportation, as well as critical control points (i.e., particle size and temperature set at 50 mm, 133°C at atmospheric pressure for 20 min, respectively) recommended by the OIE and the European Commission. The most sensitive points according to the evaluation are physical structure of the facilities (avg 42.2%), access to the facilities (avg 48.6%), and cleaning procedures (avg 51.4%). Also, indicator microorganisms (Salmonella spp., Clostridium spp., total coliforms, E. coli, E. coli O157:H7) were used to evaluate the safety in different parts of the animal meal production process. There was a prevalence of Salmonella spp. of 12.9, 14.3, and 33.3% in Meat and Bone Meal (MBM), poultry by-products, and fish meal, respectively. However, there were no significant differences (P = 0.73) in the prevalence between the different animal meals, according to the data collected. It was also observed that renderings associated with the poultry industry (i.e., 92.0%) obtained the best ratings overall, which reflects a satisfactory development of this sector and the integration of its production system as a whole. PMID:29562297

  20. Higher Education Facilities: The SmartGrid Earns a Doctorate in Economics

    ERIC Educational Resources Information Center

    Tysseling, John C.; Zibelman, Audrey; Freifeld, Allen

    2011-01-01

    Most higher education facilities have already accomplished some measure of a "microgrid" investment with building control systems (BCS), energy management systems (EMS), and advanced metering infrastructure (AMI) installations. Available energy production facilities may include boilers, chillers, cogeneration, thermal storage, electrical…

  1. A Field Investigation and Facility Review of Eight Modular Starved-Air Heat Recovery Incinerator Systems.

    DTIC Science & Technology

    1984-10-01

    are shared with the production facility. I Capital Costs: $260,000 (1976) plus $45,000 for the building. Operating and Maintenance Costs: O&M costs are...agricultural product processing plant. Operation: Three shifts, 5.5 days/week, 52 weeks/year. Capital Costs: Total capital cost S1,400,000 (1981...which makes their operating and maintenance costs, waste tonnages, ; and steam production readily available. Sample Data (All Numbers Rounded) 1st

  2. An outdoor test facility for the large-scale production of microalgae

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Johnson, D.A.; Weissman, J.; Goebel, R.

    The goal of the US Department of EnergySolar Energy Research Institute's Aquatic Species Program is to develop the technology base to produce liquid fuels from microalgae. This technology is being initially developed for the desert Southwest. As part of this program an outdoor test facility has been designed and constructed in Roswell, New Mexico. The site has a large existing infrastructure, a suitable climate, and abundant saline groundwater. This facility will be used to evaluate productivity of microalgae strains and conduct large-scale experiments to increase biomass productivity while decreasing production costs. Six 3-m/sup 2/ fiberglass raceways were constructed. Several microalgaemore » strains were screened for growth, one of which had a short-term productivity rate of greater than 50 g dry wt m/sup /minus/2/ d/sup /minus/1/. Two large-scale, 0.1-ha raceways have also been built. These are being used to evaluate the performance trade-offs between low-cost earthen liners and higher cost plastic liners. A series of hydraulic measurements is also being carried out to evaluate future improved pond designs. Future plans include a 0.5-ha pond, which will be built in approximately 2 years to test a scaled-up system. This unique facility will be available to other researchers and industry for studies on microalgae productivity. 6 refs., 9 figs., 1 tab.« less

  3. The regulatory framework for preventing cross-contamination of pharmaceutical products: History and considerations for the future.

    PubMed

    Sargent, Edward V; Flueckiger, Andreas; Barle, Ester Lovsin; Luo, Wendy; Molnar, Lance R; Sandhu, Reena; Weideman, Patricia A

    2016-08-01

    Cross-contamination in multi-product pharmaceutical manufacturing facilities can impact both product safety and quality. This issue has been recognized by regulators and industry for some time, leading to publication of a number of continually evolving guidelines. This manuscript provides a historical overview of the regulatory framework for managing cross-contamination in multi-product facilities to provide context for current approaches. Early guidelines focused on the types of pharmaceuticals for which dedicated facilities and control systems were needed, and stated the requirements for cleaning validation. More recent guidelines have promoted the idea of using Acceptable Daily Exposures (ADEs) to establish cleaning limits for actives and other potentially hazardous substances. The ADE approach is considered superior to previous methods for setting cleaning limits such as using a predetermined general limit (e.g., 10 ppm or a fraction of the median lethal dose (LD50) or therapeutic dose). The ADEs can be used to drive the cleaning process and as part of the overall assessment of whether dedicated production facilities are required. While great strides have been made in using the ADE approach, work remains to update good manufacturing practices (GMPs) to ensure that the approaches are clear, consistent with the state-of-the-science, and broadly applicable yet flexible enough for adaptation to unique products and situations. Copyright © 2016 Elsevier Inc. All rights reserved.

  4. Potential occupational risk of amines in carbon capture for power generation.

    PubMed

    Gentry, P Robinan; House-Knight, Tamara; Harris, Angela; Greene, Tracy; Campleman, Sharan

    2014-08-01

    While CO2 capture and storage (CCS) technology has been well studied in terms of its efficacy and cost of implementation, there is limited available data concerning the potential for occupational exposure to amines, mixtures of amines, or degradation of by-products from the CCS process. This paper is a critical review of the available data concerning the potential effects of amines and CCS-degradation by-products. A comprehensive review of the occupational health and safety issues associated with exposure to amines and amine by-products at CCS facilities was performed, along with a review of the regulatory status and guidelines of amines, by-products, and CCS process vapor mixtures. There are no specific guidelines or regulations regarding permissible levels of exposure via air for amines and degradation products that could form atmospheric oxidation of amines released from post-combustion CO2 capture plants. While there has been a worldwide effort to develop legal and regulatory frameworks for CCS, none are directly related to occupational exposures. By-products of alkanolamine degradation may pose the most significant health hazard to workers in CCS facilities, with several aldehydes, amides, nitramines, and nitrosamines classified as either known or potential/possible human carcinogens. The absence of large-scale CCS facilities; absence and unreliability of reported data in the literature from pilot facilities; and proprietary amine blends make it difficult to estimate potential amine exposures and predict formation and exposure to degradation products.

  5. A Study of the Feasibility of a Centralized Instructional Television Production Facility for Higher Education Institutions in Utah.

    ERIC Educational Resources Information Center

    Toyn, Thomas David

    The author sought to evaluate the feasibility of developing a centralized instructional television (ITV) production facility for institutions of higher learning in the state of Utah. He considered economic factors, availability of qualified personnel, space and physical plant, potential to provide the required service, and the degree of acceptance…

  6. Production facility site selection factors for Texas value-added wood producers

    Treesearch

    Judd H. Michael; Joanna Teitel; James E. Granskog

    1998-01-01

    Value-added wood products manufacturers serve an important role in the economies of many U.S. regions and are therefore sought after by entities such as economic development agencies. The reasons why certain locations for a prospective prodution facility would be more attractive to secondary wood industry producers are not clearly understood. Therefore, this research...

  7. 48 CFR 241.102 - Applicability.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... authorized by— (A) 10 U.S.C. 2394 for energy, fuels, and energy production facilities for periods not to exceed 30 years; (B) 10 U.S.C. 2394a for renewable energy for periods not to exceed 25 years; (C) 10 U.S.C. 2689 for geothermal resources that result in energy production facilities; (D) 10 U.S.C. 2809 for...

  8. 48 CFR 241.102 - Applicability.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... authorized by— (A) 10 U.S.C. 2394 for energy, fuels, and energy production facilities for periods not to exceed 30 years; (B) 10 U.S.C. 2394a for renewable energy for periods not to exceed 25 years; (C) 10 U.S.C. 2689 for geothermal resources that result in energy production facilities; (D) 10 U.S.C. 2809 for...

  9. 10 CFR 50.13 - Attacks and destructive acts by enemies of the United States; and defense activities.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... LICENSING OF PRODUCTION AND UTILIZATION FACILITIES Requirement of License, Exceptions § 50.13 Attacks and... construct and operate a production or utilization facility, or for an amendment to such license, is not required to provide for design features or other measures for the specific purpose of protection against...

  10. APPLICATION OF STANDARDIZED QUALITY CONTROL PROCEDURES TO OPEN-PATH FOURIER TRANSFORM INFRARED DATA COLLECTED AT A CONCENTRATED SWINE PRODUCTION FACILITY

    EPA Science Inventory

    Open-path Fourier transform infrared (OP/FT-IR) spectrometry was used to measure the concentrations of ammonia, methane, and other atmospheric eases at a concentrated swine production facility. A total of 2200 OP/FT-IR spectra were acquired along nine different monitoring paths d...

  11. 9 CFR 71.7 - Means of conveyance, facilities, premises, and cages and other equipment; methods of cleaning and...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 9 Animals and Animal Products 1 2011-01-01 2011-01-01 false Means of conveyance, facilities, premises, and cages and other equipment; methods of cleaning and disinfecting. 71.7 Section 71.7 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE INTERSTATE...

  12. 9 CFR 71.4 - Maintenance of certain facilities and premises in a sanitary condition required; cleaning and...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 9 Animals and Animal Products 1 2014-01-01 2014-01-01 false Maintenance of certain facilities and premises in a sanitary condition required; cleaning and disinfection, when required; animals classed as âexposed.â 71.4 Section 71.4 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE...

  13. 9 CFR 71.7 - Means of conveyance, facilities, premises, and cages and other equipment; methods of cleaning and...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 9 Animals and Animal Products 1 2014-01-01 2014-01-01 false Means of conveyance, facilities, premises, and cages and other equipment; methods of cleaning and disinfecting. 71.7 Section 71.7 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE INTERSTATE...

  14. 9 CFR 71.4 - Maintenance of certain facilities and premises in a sanitary condition required; cleaning and...

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 9 Animals and Animal Products 1 2013-01-01 2013-01-01 false Maintenance of certain facilities and premises in a sanitary condition required; cleaning and disinfection, when required; animals classed as âexposed.â 71.4 Section 71.4 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE...

  15. 9 CFR 71.4 - Maintenance of certain facilities and premises in a sanitary condition required; cleaning and...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Maintenance of certain facilities and premises in a sanitary condition required; cleaning and disinfection, when required; animals classed as âexposed.â 71.4 Section 71.4 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE...

  16. 9 CFR 71.4 - Maintenance of certain facilities and premises in a sanitary condition required; cleaning and...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 9 Animals and Animal Products 1 2011-01-01 2011-01-01 false Maintenance of certain facilities and premises in a sanitary condition required; cleaning and disinfection, when required; animals classed as âexposed.â 71.4 Section 71.4 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE...

  17. 9 CFR 71.7 - Means of conveyance, facilities, premises, and cages and other equipment; methods of cleaning and...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Means of conveyance, facilities, premises, and cages and other equipment; methods of cleaning and disinfecting. 71.7 Section 71.7 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE INTERSTATE...

  18. 9 CFR 71.7 - Means of conveyance, facilities, premises, and cages and other equipment; methods of cleaning and...

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 9 Animals and Animal Products 1 2013-01-01 2013-01-01 false Means of conveyance, facilities, premises, and cages and other equipment; methods of cleaning and disinfecting. 71.7 Section 71.7 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE INTERSTATE...

  19. 9 CFR 71.4 - Maintenance of certain facilities and premises in a sanitary condition required; cleaning and...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 9 Animals and Animal Products 1 2012-01-01 2012-01-01 false Maintenance of certain facilities and premises in a sanitary condition required; cleaning and disinfection, when required; animals classed as âexposed.â 71.4 Section 71.4 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE...

  20. 9 CFR 71.7 - Means of conveyance, facilities, premises, and cages and other equipment; methods of cleaning and...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 9 Animals and Animal Products 1 2012-01-01 2012-01-01 false Means of conveyance, facilities, premises, and cages and other equipment; methods of cleaning and disinfecting. 71.7 Section 71.7 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE INTERSTATE...

  1. 40 CFR 63.11601 - What are the standards for new and existing paints and allied products manufacturing facilities?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... existing paints and allied products manufacturing facilities? 63.11601 Section 63.11601 Protection of..., and Compliance Requirements § 63.11601 What are the standards for new and existing paints and allied... must add the dry pigments and solids that contain compounds of cadmium, chromium, lead, or nickel and...

  2. 40 CFR 63.11601 - What are the standards for new and existing paints and allied products manufacturing facilities?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... existing paints and allied products manufacturing facilities? 63.11601 Section 63.11601 Protection of..., and Compliance Requirements § 63.11601 What are the standards for new and existing paints and allied... must add the dry pigments and solids that contain compounds of cadmium, chromium, lead, or nickel and...

  3. 40 CFR 372.22 - Covered facilities for toxic chemical release reporting.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... employees. (b) The facility is in a Standard Industrial Classification (SIC) (as in effect on January 1... one of the following is true: (i) The sum of the value of services provided and/or products shipped... greater than 50 percent of the total value of all services provided and/or products shipped from and/or...

  4. Voluntary Medical Male Circumcision Scale-Up in Nyanza, Kenya: Evaluating Technical Efficiency and Productivity of Service Delivery

    PubMed Central

    Omondi Aduda, Dickens S.; Ouma, Collins; Onyango, Rosebella; Onyango, Mathews; Bertrand, Jane

    2015-01-01

    Background Voluntary medical male circumcision (VMMC) service delivery is complex and resource-intensive. In Kenya’s context there is still paucity of information on resource use vis-à-vis outputs as programs scale up. Knowledge of technical efficiency, productivity and potential sources of constraints is desirable to improve decision-making. Objective To evaluate technical efficiency and productivity of VMMC service delivery in Nyanza in 2011/2012 using data envelopment analysis. Design Comparative process evaluation of facilities providing VMMC in Nyanza in 2011/2012 using output orientated data envelopment analysis. Results Twenty one facilities were evaluated. Only 1 of 7 variables considered (total elapsed operation time) significantly improved from 32.8 minutes (SD 8.8) in 2011 to 30 minutes (SD 6.6) in 2012 (95%CI = 0.0350–5.2488; p = 0.047). Mean scale technical efficiency significantly improved from 91% (SD 19.8) in 2011 to 99% (SD 4.0) in 2012 particularly among outreach compared to fixed service delivery facilities (CI -31.47959–4.698508; p = 0.005). Increase in mean VRS technical efficiency from 84% (SD 25.3) in 2011 and 89% (SD 25.1) in 2012 was not statistically significant. Benchmark facilities were #119 and #125 in 2011 and #103 in 2012. Malmquist Productivity Index (MPI) at fixed facilities declined by 2.5% but gained by 4.9% at outreach ones by 2012. Total factor productivity improved by 83% (p = 0.032) in 2012, largely due to progress in technological efficiency by 79% (p = 0.008). Conclusions Significant improvement in scale technical efficiency among outreach facilities in 2012 was attributable to accelerated activities. However, ongoing pure technical inefficiency requires concerted attention. Technological progress was the key driver of service productivity growth in Nyanza. Incorporating service-quality dimensions and using stepwise-multiple criteria in performance evaluation enhances comprehensiveness and validity. These findings highlight site-level resource use and sources of variations in VMMC service productivity, which are important for program planning. PMID:25706119

  5. Capacity planning for batch and perfusion bioprocesses across multiple biopharmaceutical facilities.

    PubMed

    Siganporia, Cyrus C; Ghosh, Soumitra; Daszkowski, Thomas; Papageorgiou, Lazaros G; Farid, Suzanne S

    2014-01-01

    Production planning for biopharmaceutical portfolios becomes more complex when products switch between fed-batch and continuous perfusion culture processes. This article describes the development of a discrete-time mixed integer linear programming (MILP) model to optimize capacity plans for multiple biopharmaceutical products, with either batch or perfusion bioprocesses, across multiple facilities to meet quarterly demands. The model comprised specific features to account for products with fed-batch or perfusion culture processes such as sequence-dependent changeover times, continuous culture constraints, and decoupled upstream and downstream operations that permit independent scheduling of each. Strategic inventory levels were accounted for by applying cost penalties when they were not met. A rolling time horizon methodology was utilized in conjunction with the MILP model and was shown to obtain solutions with greater optimality in less computational time than the full-scale model. The model was applied to an industrial case study to illustrate how the framework aids decisions regarding outsourcing capacity to third party manufacturers or building new facilities. The impact of variations on key parameters such as demand or titres on the optimal production plans and costs was captured. The analysis identified the critical ratio of in-house to contract manufacturing organization (CMO) manufacturing costs that led the optimization results to favor building a future facility over using a CMO. The tool predicted that if titres were higher than expected then the optimal solution would allocate more production to in-house facilities, where manufacturing costs were lower. Utilization graphs indicated when capacity expansion should be considered. © 2014 The Authors Biotechnology Progress published by Wiley Periodicals, Inc. on behalf of American Institute of Chemical Engineers.

  6. Capacity Planning for Batch and Perfusion Bioprocesses Across Multiple Biopharmaceutical Facilities

    PubMed Central

    Siganporia, Cyrus C; Ghosh, Soumitra; Daszkowski, Thomas; Papageorgiou, Lazaros G; Farid, Suzanne S

    2014-01-01

    Production planning for biopharmaceutical portfolios becomes more complex when products switch between fed-batch and continuous perfusion culture processes. This article describes the development of a discrete-time mixed integer linear programming (MILP) model to optimize capacity plans for multiple biopharmaceutical products, with either batch or perfusion bioprocesses, across multiple facilities to meet quarterly demands. The model comprised specific features to account for products with fed-batch or perfusion culture processes such as sequence-dependent changeover times, continuous culture constraints, and decoupled upstream and downstream operations that permit independent scheduling of each. Strategic inventory levels were accounted for by applying cost penalties when they were not met. A rolling time horizon methodology was utilized in conjunction with the MILP model and was shown to obtain solutions with greater optimality in less computational time than the full-scale model. The model was applied to an industrial case study to illustrate how the framework aids decisions regarding outsourcing capacity to third party manufacturers or building new facilities. The impact of variations on key parameters such as demand or titres on the optimal production plans and costs was captured. The analysis identified the critical ratio of in-house to contract manufacturing organization (CMO) manufacturing costs that led the optimization results to favor building a future facility over using a CMO. The tool predicted that if titres were higher than expected then the optimal solution would allocate more production to in-house facilities, where manufacturing costs were lower. Utilization graphs indicated when capacity expansion should be considered. © 2013 The Authors Biotechnology Progress published by Wiley Periodicals, Inc. on behalf of American Institute of Chemical Engineers Biotechnol. Prog., 30:594–606, 2014 PMID:24376262

  7. Production facilities for second generation biofuels in the USA and the EU – current status and future perspectives

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Janssen, Ranier; Turhollow, Jr, Anthony F.; Rutz, Dominik

    2013-10-23

    Second generation biofuel production facilities have been slower to reach large-scale production than was anticipated a few years ago even though in Europe, the Renewable Energy Directive has incentives for, and in the United States there are also financial incentives and, the Energy Independence and Security Act of 2007 has targets for second generation biofuels. There have been a number of facilities that have been cancelled, but starting in 2013 it appears that significant quantities of second generation biofuels will be produced. A variety of conversion processes, thermal and biological, as well as hybrids of the two is being utilized.more » There will be a variety of fuels ethanol, drop-in fuels (e.g. gasoline, diesel), biodiesel, steam, electricity, bio-oil, sugars, and chemicals; and a variety of feedstocks crop residues, wood, wood wastes, energy crops, waste oils and municipal solid waste (MSW). One approach to reducing the risk of moving from first to second generation biofuel production has been to take incremental steps such as converting the cellulosic part of grains into ethanol in addition to the starch portion. Many of the second generation biofuel facilities are co-located with first generation biofuel production facilities to share infrastructure as well as trade by-products (e.g. excess steam). One of the challenges has been financing, but both private and government sources are being utilized. Private sources include internal corporate funds and debt offerings, and venture capital. Furthermore, government sources include the U.S. federal government, the European Union, European national governments, and state and local governments.« less

  8. Savannah River Plant engineering and design history. Volume 4: 300/700 Areas & general services and facilities

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1957-01-01

    The primary function of the 300 Area is the production and preparation of the fuel and target elements required for the 100 Area production reactors. Uranium slugs and lithium-aluminium alloy control and blanket rods are prepared in separate structures. Other facilities include a test pile, a physics assembly laboratory, an office and change house, an electrical substation, and various service facilities such as rail lines, roads, sewers, steam and water distribution lines, etc. The 700 Area contains housing and facilities for plant management, general plant services, and certain technical activities. The technical buildings include the Main Technical Laboratory, the Wastemore » Concentration Building, the Health Physics Headquarters, and the Health Physics Calibration building. Sections of this report describe the following: development of the 300-M Area; selection and description of process; design of main facilities of the 300 Area; development of the 700-A Area; design of the main facilities of the 700 Area; and general services and facilities, including transportation, plant protection, waste disposal and drainage, site work, pilot plants, storage, and furniture and fixtures.« less

  9. Case study project: The use of low-VOC/HAP coatings at wood furniture manufacturing facilities. Report for March 1995--March 1999

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Marshall, A.M.; Jones, J.W.; Fields, J.L.

    1999-07-01

    The paper discusses a study of pollution prevention and the use of low-VOC/HAP (volatile organic compound/hazardous air pollutant) coatings at wood furniture manufacturing facilities. The study is to identify wood furniture and cabinet manufacturing facilities that have converted to low-VOC/HAP coatings and to develop case studies for those facilities. The case studies include a discussion of the types of products each facility manufactures; the types of low-VOC/HAP coatings each facility is using; problems encountered in converting to low-VOC/HAP coatings; equipment changes that were required; costs associated with the conversion process, including capital costs associated with equipment purchases, research and developmentmore » costs, and operating costs such as operator training in new application techniques;advantages/ disadvantages of the low-VOC/HAP coatings; and customer feedback on products finished with the low-VOC/HAP coatings. The paper discusses the progress of the study and pollution prevention options at wood furniture manufacturing facilities.« less

  10. Commercialising genetically engineered animal biomedical products.

    PubMed

    Sullivan, Eddie J; Pommer, Jerry; Robl, James M

    2008-01-01

    Research over the past two decades has increased the quality and quantity of tools available to produce genetically engineered animals. The number of potentially viable biomedical products from genetically engineered animals is increasing. However, moving from cutting-edge research to development and commercialisation of a biomedical product that is useful and wanted by the public has significant challenges. Even early stage development of genetically engineered animal applications requires consideration of many steps, including quality assurance and quality control, risk management, gap analysis, founder animal establishment, cell banking, sourcing of animals and animal-derived material, animal facilities, product collection facilities and processing facilities. These steps are complicated and expensive. Biomedical applications of genetically engineered animals have had some recent successes and many applications are well into development. As researchers consider applications for their findings, having a realistic understanding of the steps involved in the development and commercialisation of a product, produced in genetically engineered animals, is useful in determining the risk of genetic modification to the animal nu. the potential public benefit of the application.

  11. The ASTROCULTURE Facility

    NASA Technical Reports Server (NTRS)

    1998-01-01

    Research with plants in microgravity offers many exciting opportunities to gain new insights and could improve products on Earth ranging from crop production to fragrances and food flavorings. The ASTROCULTURE facility is a lead commercial facility for plant growth and plant research in microgravity and was developed by the Wisconsin Center for Space Automation and Robotics (WSCAR), a NASA Commercial Space Center. On STS-95 it will support research that could help improve crop development leading to plants that are more disease resistant or have a higher yield and provide data on the production of plant essential oils---oils that contain the essence of the plant and provide both fragrance and flavoring. On STS-95, a flowering plant will be grown in ASTROCULTURE and samples taken using a method developed by the industry partner for this investigation. On Earth the samples will be analyzed by gas chromatography/mass spectrometry and the data used to evaluate both the production of fragrant oils in microgravity and in the development of one or more products.

  12. Assessment of air velocity sensors for use in animal produciton facilities

    USDA-ARS?s Scientific Manuscript database

    Ventilation is an integral part of thermal environment control in animal production facilities. Accurately measuring the air velocity distribution within these facilities is cumbersome using the traverse method and a distributed velocity measurement system would reduce the time necessary to perform ...

  13. Data Management Facility Operations Plan

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Keck, Nicole N

    2014-06-30

    The Data Management Facility (DMF) is the data center that houses several critical Atmospheric Radiation Measurement (ARM) Climate Research Facility services, including first-level data processing for the ARM Mobile Facilities (AMFs), Eastern North Atlantic (ENA), North Slope of Alaska (NSA), Southern Great Plains (SGP), and Tropical Western Pacific (TWP) sites, as well as Value-Added Product (VAP) processing, development systems, and other network services.

  14. Flow analysis of metals in a municipal solid waste management system.

    PubMed

    Jung, C H; Matsuto, T; Tanaka, N

    2006-01-01

    This study aimed to identify the metal flow in a municipal solid waste (MSW) management system. Outputs of a resource recovery facility, refuse derived fuel (RDF) production facility, carbonization facility, plastics liquefaction facility, composting facility, and bio-gasification facility were analyzed for metal content and leaching concentration. In terms of metal content, bulky and incombustible waste had the highest values. Char from a carbonization facility, which treats household waste, had a higher metal content than MSW incinerator bottom ash. A leaching test revealed that Cd and Pb in char and Pb in RDF production residue exceeded the Japanese regulatory criteria for landfilling, so special attention should be paid to final disposal of these substances. By multiplying metal content and the generation rate of outputs, the metal content of input waste to each facility was estimated. For most metals except Cr, the total contribution ratio of paper/textile/plastics, bulky waste, and incombustible waste was over 80%. Approximately 30% of Cr originated from plastic packaging. Finally, several MSW management scenarios showed that most metals are transferred to landfills and the leaching potential of metals to the environment is quite small.

  15. Flow analysis of metals in a municipal solid waste management system

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jung, C.H.; Matsuto, T.; Tanaka, N.

    2006-07-01

    This study aimed to identify the metal flow in a municipal solid waste (MSW) management system. Outputs of a resource recovery facility, refuse derived fuel (RDF) production facility, carbonization facility, plastics liquefaction facility, composting facility, and bio-gasification facility were analyzed for metal content and leaching concentration. In terms of metal content, bulky and incombustible waste had the highest values. Char from a carbonization facility, which treats household waste, had a higher metal content than MSW incinerator bottom ash. A leaching test revealed that Cd and Pb in char and Pb in RDF production residue exceeded the Japanese regulatory criteria formore » landfilling, so special attention should be paid to final disposal of these substances. By multiplying metal content and the generation rate of outputs, the metal content of input waste to each facility was estimated. For most metals except Cr, the total contribution ratio of paper/textile/plastics, bulky waste, and incombustible waste was over 80%. Approximately 30% of Cr originated from plastic packaging. Finally, several MSW management scenarios showed that most metals are transferred to landfills and the leaching potential of metals to the environment is quite small.« less

  16. Dedicated nuclear facilities for electrolytic hydrogen production

    NASA Technical Reports Server (NTRS)

    Foh, S. E.; Escher, W. J. D.; Donakowski, T. D.

    1979-01-01

    An advanced technology, fully dedicated nuclear-electrolytic hydrogen production facility is presented. This plant will produce hydrogen and oxygen only and no electrical power will be generated for off-plant use. The conceptual design was based on hydrogen production to fill a pipeline at 1000 psi and a 3000 MW nuclear base, and the base-line facility nuclear-to-shaftpower and shaftpower-to-electricity subsystems, the water treatment subsystem, electricity-to-hydrogen subsystem, hydrogen compression, efficiency, and hydrogen production cost are discussed. The final conceptual design integrates a 3000 MWth high-temperature gas-cooled reactor operating at 980 C helium reactor-out temperature, direct dc electricity generation via acyclic generators, and high-current density, high-pressure electrolyzers based on the solid polymer electrolyte approach. All subsystems are close-coupled and optimally interfaced and pipeline hydrogen is produced at 1000 psi. Hydrogen costs were about half of the conventional nuclear electrolysis process.

  17. A Single-use Strategy to Enable Manufacturing of Affordable Biologics.

    PubMed

    Jacquemart, Renaud; Vandersluis, Melissa; Zhao, Mochao; Sukhija, Karan; Sidhu, Navneet; Stout, Jim

    2016-01-01

    The current processing paradigm of large manufacturing facilities dedicated to single product production is no longer an effective approach for best manufacturing practices. Increasing competition for new indications and the launch of biosimilars for the monoclonal antibody market have put pressure on manufacturers to produce at lower cost. Single-use technologies and continuous upstream processes have proven to be cost-efficient options to increase biomass production but as of today the adoption has been only minimal for the purification operations, partly due to concerns related to cost and scale-up. This review summarizes how a single-use holistic process and facility strategy can overcome scale limitations and enable cost-efficient manufacturing to support the growing demand for affordable biologics. Technologies enabling high productivity, right-sized, small footprint, continuous, and automated upstream and downstream operations are evaluated in order to propose a concept for the flexible facility of the future.

  18. Biofilm formation and ethanol inhibition by bacterial contaminants of biofuel fermentation.

    PubMed

    Rich, Joseph O; Leathers, Timothy D; Bischoff, Kenneth M; Anderson, Amber M; Nunnally, Melinda S

    2015-11-01

    Bacterial contaminants can inhibit ethanol production in biofuel fermentations, and even result in stuck fermentations. Contaminants may persist in production facilities by forming recalcitrant biofilms. A two-year longitudinal study was conducted of bacterial contaminants from a Midwestern dry grind corn fuel ethanol facility. Among eight sites sampled in the facility, the combined liquefaction stream and yeast propagation tank were consistently contaminated, leading to contamination of early fermentation tanks. Among 768 contaminants isolated, 92% were identified as Lactobacillus sp., with the most abundant species being Lactobacillus plantarum, Lactobacillus casei, Lactobacillus mucosae, and Lactobacillus fermentum. Seven percent of total isolates showed the ability to form biofilms in pure cultures, and 22% showed the capacity to significantly inhibit ethanol production. However, these traits were not correlated. Ethanol inhibition appeared to be related to acetic acid production by contaminants, particularly by obligately heterofermentative species such as L. fermentum and L. mucosae. Published by Elsevier Ltd.

  19. Electrical-thermal-structural finite element simulation and experimental study of a plasma ion source for the production of radioactive ion beams

    NASA Astrophysics Data System (ADS)

    Manzolaro, M.; Meneghetti, G.; Andrighetto, A.; Vivian, G.

    2016-03-01

    The production target and the ion source constitute the core of the selective production of exotic species (SPES) facility. In this complex experimental apparatus for the production of radioactive ion beams, a 40 MeV, 200 μA proton beam directly impinges a uranium carbide target, generating approximately 1013 fissions per second. The transfer line enables the unstable isotopes generated by the 238U fissions in the target to reach the ion source, where they can be ionized and finally accelerated to the subsequent areas of the facility. In this work, the plasma ion source currently adopted for the SPES facility is analyzed in detail by means of electrical, thermal, and structural numerical models. Next, theoretical results are compared with the electric potential difference, temperature, and displacement measurements. Experimental tests with stable ion beams are also presented and discussed.

  20. Metal Exposures at three U.S. electronic scrap recycling facilities.

    PubMed

    Ceballos, Diana; Beaucham, Catherine; Page, Elena

    2017-06-01

    Many metals found in electronic scrap are known to cause serious health effects, including but not limited to cancer and respiratory, neurologic, renal, and reproductive damage. The National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention performed three health hazard evaluations at electronic scrap recycling facilities in the U.S. to characterize employee exposure to metals and recommend control strategies to reduce these exposures. We performed air, surface, and biological monitoring for metals. We found one overexposure to lead and two overexposures to cadmium. We found metals on non-production surfaces, and the skin and clothing of workers before they left work in all of the facilities. We also found some elevated blood lead levels (above 10 micrograms per deciliter), however no employees at any facility had detectable mercury in their urine or exceeded 34% of the OELs for blood or urine cadmium. This article focuses on sampling results for lead, cadmium, mercury, and indium. We provided recommendations for improving local exhaust ventilation, reducing the recirculation of potentially contaminated air, using respirators until exposures are controlled, and reducing the migration of contaminants from production to non-production areas. We also recommended ways for employees to prevent taking home metal dust by using work uniforms laundered on-site, storing personal and work items in separate lockers, and using washing facilities equipped with lead-removing cleaning products.

  1. Efficiency of U.S. Dialysis Centers: An Updated Examination of Facility Characteristics That Influence Production of Dialysis Treatments

    PubMed Central

    Shreay, Sanatan; Ma, Martin; McCluskey, Jill; Mittelhammer, Ron C; Gitlin, Matthew; Stephens, J Mark

    2014-01-01

    Objective To explore the relative efficiency of dialysis facilities in the United States and identify factors that are associated with efficiency in the production of dialysis treatments. Data Sources/Study Setting Medicare cost report data from 4,343 free-standing dialysis facilities in the United States that offered in-center hemodialysis in 2010. Study Design A cross-sectional, facility-level retrospective database analysis, utilizing data envelopment analysis (DEA) to estimate facility efficiency. Data Collection/Extraction Methods Treatment data and cost and labor inputs of dialysis treatments were obtained from 2010 Medicare Renal Cost Reports. Demographic data were obtained from the 2010 U.S. Census. Principal Findings Only 26.6 percent of facilities were technically efficient. Neither the intensity of market competition nor the profit status of the facility had a significant effect on efficiency. Facilities that were members of large chains were less likely to be efficient. Cost and labor savings due to changes in drug protocols had little effect on overall dialysis center efficiency. Conclusions The majority of free-standing dialysis facilities in the United States were functioning in a technically inefficient manner. As payment systems increasingly employ capitation and bundling provisions, these institutions will need to evaluate their efficiency to remain competitive. PMID:24237043

  2. Volatile Organic Compound Emissions from Natural Gas Facilities in the Denver-Julesburg Basin, the Uintah Basin and the Marcellus Shale

    NASA Astrophysics Data System (ADS)

    Li, X.; Omara, M.; Sullivan, M.; Subramanian, R.; Robinson, A. L.; Presto, A. A.

    2015-12-01

    Natural gas has been widely considered as a "bridge" fuel in the future. Because of the rapid advancement of horizontal drilling and hydraulic fracturing techniques, the production of crude oil and natural gas in US increased dramatically in recent years; and currently natural gas contributes to about 25% of total US energy consumption. Recent studies suggest that shale gas extraction facilities may emit Volatile Organic Compounds (VOCs), which could contribute to the formation of ozone and affect regional air quality, public health and climate change. In this study we visited 37 natural gas facilities in Denver-Julesburg and Uintah Basins from March to May, 2015. VOCs and methane concentrations were measured downwind of individual facilities with our mobile lab. In total 13 VOCs, including benzene and toluene, were measured by a SRI 8610C Gas Chromatograph. Similar measurements will be conducted in the Marcellus Shale in late August 2015. Preliminary results show that VOC emissions from individual shale gas facilities are variable, which suggests that a single VOC profile may not characterize all natural gas production facilities, though there may be some common characteristics. Measured VOC concentrations will be normalized to concurrently-measured methane emissions, and coupled with methane emission rates measured at these facilities, used to obtain VOC emission factors from natural gas production. This presentation will also compare VOC emission rates from the Marcellus shale with that from the Denver-Julesburg and Uintah basins.

  3. A geographical assessment of vegetation carbon stocks and greenhouse gas emissions on potential microalgae-based biofuel facilities in the United States.

    PubMed

    Quiroz Arita, Carlos; Yilmaz, Özge; Barlak, Semin; Catton, Kimberly B; Quinn, Jason C; Bradley, Thomas H

    2016-12-01

    The microalgae biofuels life cycle assessments (LCA) present in the literature have excluded the effects of direct land use change (DLUC) from facility construction under the assumption that DLUC effects are negligible. This study seeks to model the greenhouse gas (GHG) emissions of microalgae biofuels including DLUC by quantifying the CO 2 equivalence of carbon released to the atmosphere through the construction of microalgae facilities. The locations and types of biomass and Soil Organic Carbon that are disturbed through microalgae cultivation facility construction are quantified using geographical models of microalgae productivity potential including consideration of land availability. The results of this study demonstrate that previous LCA of microalgae to biofuel processes have overestimated GHG benefits of microalgae-based biofuels production by failing to include the effect of DLUC. Previous estimations of microalgae biofuel production potential have correspondingly overestimated the volume of biofuels that can be produced in compliance with U.S. environmental goals. Copyright © 2016 Elsevier Ltd. All rights reserved.

  4. Mines and mineral processing facilities in the vicinity of the March 11, 2011, earthquake in northern Honshu, Japan

    USGS Publications Warehouse

    Menzie, W. David; Baker, Michael S.; Bleiwas, Donald I.; Kuo, Chin

    2011-01-01

    U.S. Geological Survey data indicate that the area affected by the March 11, 2011, magnitude 9.0 earthquake and associated tsunami is home to nine cement plants, eight iodine plants, four iron and steel plants, four limestone mines, three copper refineries, two gold refineries, two lead refineries, two zinc refineries, one titanium dioxide plant, and one titanium sponge processing facility. These facilities have the capacity to produce the following percentages of the world's nonfuel mineral production: 25 percent of iodine, 10 percent of titanium sponge (metal), 3 percent of refined zinc, 2.5 percent of refined copper, and 1.4 percent of steel. In addition, the nine cement plants contribute about one-third of Japan's cement annual production. The iodine is a byproduct from production of natural gas at the Miniami Kanto gas field, east of Tokyo in Chiba Prefecture. Japan is the world's second leading (after Chile) producer of iodine, which is processed in seven nearby facilities.

  5. 36 CFR 703.7 - Public Reading Facility.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ....7 Section 703.7 Parks, Forests, and Public Property LIBRARY OF CONGRESS DISCLOSURE OR PRODUCTION OF RECORDS OR INFORMATION Availability of Library of Congress Records § 703.7 Public Reading Facility. (a) The Chief, OSS, shall maintain a reading facility for the public inspection and copying of Library...

  6. 36 CFR 703.7 - Public Reading Facility.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ....7 Section 703.7 Parks, Forests, and Public Property LIBRARY OF CONGRESS DISCLOSURE OR PRODUCTION OF RECORDS OR INFORMATION Availability of Library of Congress Records § 703.7 Public Reading Facility. (a) The Chief, OSS, shall maintain a reading facility for the public inspection and copying of Library...

  7. 36 CFR 703.7 - Public Reading Facility.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ....7 Section 703.7 Parks, Forests, and Public Property LIBRARY OF CONGRESS DISCLOSURE OR PRODUCTION OF RECORDS OR INFORMATION Availability of Library of Congress Records § 703.7 Public Reading Facility. (a) The Chief, OSS, shall maintain a reading facility for the public inspection and copying of Library...

  8. 36 CFR 703.7 - Public Reading Facility.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ....7 Section 703.7 Parks, Forests, and Public Property LIBRARY OF CONGRESS DISCLOSURE OR PRODUCTION OF RECORDS OR INFORMATION Availability of Library of Congress Records § 703.7 Public Reading Facility. (a) The Chief, OSS, shall maintain a reading facility for the public inspection and copying of Library...

  9. 43 CFR 3272.11 - How do I describe the proposed utilization facility?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...) BUREAU OF LAND MANAGEMENT, DEPARTMENT OF THE INTERIOR MINERALS MANAGEMENT (3000) GEOTHERMAL RESOURCE... proposed facility operations, including estimated total production and injection rates; estimated well flow... site(s); (e) The source, quality, and proposed consumption rate of water to be used during facility...

  10. 27 CFR 20.165 - Storage facilities.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2011-04-01 2011-04-01 false Storage facilities. 20.165... Users of Specially Denatured Spirits Premises and Equipment § 20.165 Storage facilities. (a) Storerooms... for locking. (b) Each stationary tank used for the storage of specially denatured spirits shall be...

  11. 27 CFR 20.165 - Storage facilities.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Storage facilities. 20.165... Users of Specially Denatured Spirits Premises and Equipment § 20.165 Storage facilities. (a) Storerooms... for locking. (b) Each stationary tank used for the storage of specially denatured spirits shall be...

  12. 27 CFR 20.165 - Storage facilities.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2012-04-01 2012-04-01 false Storage facilities. 20.165... Users of Specially Denatured Spirits Premises and Equipment § 20.165 Storage facilities. (a) Storerooms... for locking. (b) Each stationary tank used for the storage of specially denatured spirits shall be...

  13. 27 CFR 20.165 - Storage facilities.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2013-04-01 2013-04-01 false Storage facilities. 20.165... Users of Specially Denatured Spirits Premises and Equipment § 20.165 Storage facilities. (a) Storerooms... for locking. (b) Each stationary tank used for the storage of specially denatured spirits shall be...

  14. 27 CFR 20.165 - Storage facilities.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2014-04-01 2014-04-01 false Storage facilities. 20.165... Users of Specially Denatured Spirits Premises and Equipment § 20.165 Storage facilities. (a) Storerooms... for locking. (b) Each stationary tank used for the storage of specially denatured spirits shall be...

  15. 27 CFR 24.41 - Office facilities.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Office facilities. 24.41... § 24.41 Office facilities. The appropriate TTB officer may require the proprietor to furnish... performing Government duties whether or not such office space is located at the specific premises where...

  16. 76 FR 64055 - Special Rules Governing Certain Information Obtained Under the Clean Air Act: Technical Correction

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-17

    ... natural gas. 211112 Natural gas liquid extraction facilities. Petrochemical Production....... 32511... facilities. 211112 Natural gas liquid extraction facilities. Suppliers of Industrial 325120 Industrial gas... reference in EPA's procedures for handling data collected under the Mandatory Greenhouse Gas Reporting Rule...

  17. Integrated Component-based Data Acquisition Systems for Aerospace Test Facilities

    NASA Technical Reports Server (NTRS)

    Ross, Richard W.

    2001-01-01

    The Multi-Instrument Integrated Data Acquisition System (MIIDAS), developed by the NASA Langley Research Center, uses commercial off the shelf (COTS) products, integrated with custom software, to provide a broad range of capabilities at a low cost throughout the system s entire life cycle. MIIDAS combines data acquisition capabilities with online and post-test data reduction computations. COTS products lower purchase and maintenance costs by reducing the level of effort required to meet system requirements. Object-oriented methods are used to enhance modularity, encourage reusability, and to promote adaptability, reducing software development costs. Using only COTS products and custom software supported on multiple platforms reduces the cost of porting the system to other platforms. The post-test data reduction capabilities of MIIDAS have been installed at four aerospace testing facilities at NASA Langley Research Center. The systems installed at these facilities provide a common user interface, reducing the training time required for personnel that work across multiple facilities. The techniques employed by MIIDAS enable NASA to build a system with a lower initial purchase price and reduced sustaining maintenance costs. With MIIDAS, NASA has built a highly flexible next generation data acquisition and reduction system for aerospace test facilities that meets customer expectations.

  18. National Institutes of Health-Sponsored Clinical Islet Transplantation Consortium Phase 3 Trial: Manufacture of a Complex Cellular Product at Eight Processing Facilities.

    PubMed

    Ricordi, Camillo; Goldstein, Julia S; Balamurugan, A N; Szot, Gregory L; Kin, Tatsuya; Liu, Chengyang; Czarniecki, Christine W; Barbaro, Barbara; Bridges, Nancy D; Cano, Jose; Clarke, William R; Eggerman, Thomas L; Hunsicker, Lawrence G; Kaufman, Dixon B; Khan, Aisha; Lafontant, David-Erick; Linetsky, Elina; Luo, Xunrong; Markmann, James F; Naji, Ali; Korsgren, Olle; Oberholzer, Jose; Turgeon, Nicole A; Brandhorst, Daniel; Chen, Xiaojuan; Friberg, Andrew S; Lei, Ji; Wang, Ling-Jia; Wilhelm, Joshua J; Willits, Jamie; Zhang, Xiaomin; Hering, Bernhard J; Posselt, Andrew M; Stock, Peter G; Shapiro, A M James; Chen, Xiaojuan

    2016-11-01

    Eight manufacturing facilities participating in the National Institutes of Health-sponsored Clinical Islet Transplantation (CIT) Consortium jointly developed and implemented a harmonized process for the manufacture of allogeneic purified human pancreatic islet (PHPI) product evaluated in a phase 3 trial in subjects with type 1 diabetes. Manufacturing was controlled by a common master production batch record, standard operating procedures that included acceptance criteria for deceased donor organ pancreata and critical raw materials, PHPI product specifications, certificate of analysis, and test methods. The process was compliant with Current Good Manufacturing Practices and Current Good Tissue Practices. This report describes the manufacturing process for 75 PHPI clinical lots and summarizes the results, including lot release. The results demonstrate the feasibility of implementing a harmonized process at multiple facilities for the manufacture of a complex cellular product. The quality systems and regulatory and operational strategies developed by the CIT Consortium yielded product lots that met the prespecified characteristics of safety, purity, potency, and identity and were successfully transplanted into 48 subjects. No adverse events attributable to the product and no cases of primary nonfunction were observed. © 2016 by the American Diabetes Association.

  19. National Institutes of Health–Sponsored Clinical Islet Transplantation Consortium Phase 3 Trial: Manufacture of a Complex Cellular Product at Eight Processing Facilities

    PubMed Central

    Balamurugan, A.N.; Szot, Gregory L.; Kin, Tatsuya; Liu, Chengyang; Czarniecki, Christine W.; Barbaro, Barbara; Bridges, Nancy D.; Cano, Jose; Clarke, William R.; Eggerman, Thomas L.; Hunsicker, Lawrence G.; Kaufman, Dixon B.; Khan, Aisha; Lafontant, David-Erick; Linetsky, Elina; Luo, Xunrong; Markmann, James F.; Naji, Ali; Korsgren, Olle; Oberholzer, Jose; Turgeon, Nicole A.; Brandhorst, Daniel; Chen, Xiaojuan; Friberg, Andrew S.; Lei, Ji; Wang, Ling-jia; Wilhelm, Joshua J.; Willits, Jamie; Zhang, Xiaomin; Hering, Bernhard J.; Posselt, Andrew M.; Stock, Peter G.; Shapiro, A.M. James

    2016-01-01

    Eight manufacturing facilities participating in the National Institutes of Health–sponsored Clinical Islet Transplantation (CIT) Consortium jointly developed and implemented a harmonized process for the manufacture of allogeneic purified human pancreatic islet (PHPI) product evaluated in a phase 3 trial in subjects with type 1 diabetes. Manufacturing was controlled by a common master production batch record, standard operating procedures that included acceptance criteria for deceased donor organ pancreata and critical raw materials, PHPI product specifications, certificate of analysis, and test methods. The process was compliant with Current Good Manufacturing Practices and Current Good Tissue Practices. This report describes the manufacturing process for 75 PHPI clinical lots and summarizes the results, including lot release. The results demonstrate the feasibility of implementing a harmonized process at multiple facilities for the manufacture of a complex cellular product. The quality systems and regulatory and operational strategies developed by the CIT Consortium yielded product lots that met the prespecified characteristics of safety, purity, potency, and identity and were successfully transplanted into 48 subjects. No adverse events attributable to the product and no cases of primary nonfunction were observed. PMID:27465220

  20. Design, fabrication, and integration testing of the Garden Banks 388 subsea production template

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ledbetter, W.R.; Smith, D.W.; Pierce, D.M.

    1995-12-31

    Enserch Exploration`s Garden Banks 388 development has a production scheme based around a floating drilling and production facility and subsea drilling/production template. The Floating Production Facility (FPF) is a converted semisubmersible drilling rig that will drill and produce through a 24-well slot subsea template. This development is located in Block 388 of the Garden Banks area in the Gulf of Mexico approximately 200 miles southwest of New Orleans, Louisiana. The production system is being installed in an area of known oil and gas reserves and will produce to a shallow water platform 54 miles away at Eugene Island 315. Themore » FPF will be permanently moored above the template. The subsea template has been installed in 2190 feet of water and will produce through a 2,000 foot free-standing production riser system to the FPF. The produced fluids are partially separated on the FPF before oil and gas are pumped through the template to export gathering lines that are connected to the shallow water facility. The system designed through-put is 40,000 BOPD of oil and 120 MMSCFD of gas.« less

  1. 76 FR 11280 - Notice of Lodging of an Amendment to Consent Decree Under the Clean Air Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-01

    ... Kilns 22 and 23 at Lafarge's Alpena, Michigan cement production facility. The proposed Amendment to the... both Kilns 22 and 23 at its Alpena, Michigan cement production facility, rather than the two Wet FGDs... three months earlier than currently required in the decree for one of the Alpena cement kilns; (2...

  2. Chemical Weapons Disposal: Improvements Needed in Program Accountability and Financial Management

    DTIC Science & Technology

    2000-05-01

    United States General Accounting Office PAQ Report to Congressional Committees May 2000 CHEMICAL WEAPONS DISPOSAL Improvements Needed in Program...warfare materiel, and former production facilities and identify and locate buried chemical warfare materiel. Alternative Technologies and Approaches...production facilities, and buried chemical warfare materiel. These items are described in table 1. Table 1: Nonstockpile Chemical Materiel Category

  3. 7 CFR Appendix C to Subpart E of... - Guidelines for Loan Guarantees for Alcohol Fuel Production Facilities

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 14 2012-01-01 2012-01-01 false Guidelines for Loan Guarantees for Alcohol Fuel Production Facilities C Appendix C to Subpart E of Part 1980 Agriculture Regulations of the Department of... Business and Industrial Loan Program Pt. 1980, Subpt. E, App. C Appendix C to Subpart E of Part 1980...

  4. 7 CFR Appendix C to Subpart E of... - Guidelines for Loan Guarantees for Alcohol Fuel Production Facilities

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 14 2011-01-01 2011-01-01 false Guidelines for Loan Guarantees for Alcohol Fuel Production Facilities C Appendix C to Subpart E of Part 1980 Agriculture Regulations of the Department of... Business and Industrial Loan Program Pt. 1980, Subpt. E, App. C Appendix C to Subpart E of Part 1980...

  5. CONCEPTUAL DESIGN ASSESSMENT FOR THE CO-FIRING OF BIO-REFINERY SUPPLIED LIGNIN PROJECT

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ted Berglund; Jeffrey T. Ranney; Carol L. Babb

    2001-01-01

    The major aspects of this project are proceeding toward completion. Prior to this quarter, design criteria, tentative site selection, facility layout, and preliminary facility cost estimates have been completed and issued for review. Processing of bio-solids was completed, providing material for the pilot operations. Pilot facility design, equipment selection, and modification were completed during the fourth quarter. Initial pilot facility shakedown was completed during the fourth quarter. During pilot plant shakedown operations, several production batch test runs were performed. These pilot tests were coupled with laboratory testing to confirm pilot results. In initial batches of operations, cellulose to glucose conversionsmore » of 62.5% and 64.8% were observed in laboratory hydrolysis. As part of this testing, lignin dewatering was tested using laboratory and vendor-supplied filtration equipment. Dewatering tests reported moisture contents in the lignin of between 50% and 60%. Dewatering parameters and options will continue to be investigated during lignin production. After some unavoidable delays, a suitable representative supply of MSW feed material was procured. Shredding of the feed material was completed and final drying of the feed is expected to be completed by late January. Once feed drying is completed, pilot facility production will begin to produce lignin for co-fire testing. Facility modifications are expected to continue to improve facility operations and performance during the first quarter of 2001. The TVA-Colbert facility continues to make progress in evaluating the co-location of the Masada facility on the operation of the power generation facility. The TVA-Colbert fossil plant is fully capable of providing a reliable steam supply. The preferred steam supply connection points and steam pipeline routing have been identified. The environmental review of the pipeline routing has been completed and no major impacts have been identified. Detailed assessment of steam export impacts on the Colbert boiler system continues.« less

  6. 9 CFR 355.14 - Facilities.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... CERTIFICATION CERTIFIED PRODUCTS FOR DOGS, CATS, AND OTHER CARNIVORA; INSPECTION, CERTIFICATION, AND... inspector. These facilities shall be set apart for this purpose and provided with lockers suitable for the...

  7. 40 CFR 60.420 - Applicability and designation of affected facility.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Performance for Ammonium Sulfate Manufacture § 60.420 Applicability and designation of affected facility. (a) The affected facility to which the provisions of this subpart apply is each ammonium sulfate dryer within an ammonium sulfate manufacturing plant in the caprolactam by-product, synthetic, and coke oven by...

  8. 40 CFR 60.420 - Applicability and designation of affected facility.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Performance for Ammonium Sulfate Manufacture § 60.420 Applicability and designation of affected facility. (a) The affected facility to which the provisions of this subpart apply is each ammonium sulfate dryer within an ammonium sulfate manufacturing plant in the caprolactam by-product, synthetic, and coke oven by...

  9. 40 CFR 60.420 - Applicability and designation of affected facility.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Performance for Ammonium Sulfate Manufacture § 60.420 Applicability and designation of affected facility. (a) The affected facility to which the provisions of this subpart apply is each ammonium sulfate dryer within an ammonium sulfate manufacturing plant in the caprolactam by-product, synthetic, and coke oven by...

  10. 40 CFR 60.420 - Applicability and designation of affected facility.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Performance for Ammonium Sulfate Manufacture § 60.420 Applicability and designation of affected facility. (a) The affected facility to which the provisions of this subpart apply is each ammonium sulfate dryer within an ammonium sulfate manufacturing plant in the caprolactam by-product, synthetic, and coke oven by...

  11. 40 CFR 60.500 - Applicability and designation of affected facility.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Performance for Bulk Gasoline Terminals § 60.500 Applicability and designation of affected facility. (a) The... bulk gasoline terminal which deliver liquid product into gasoline tank trucks. (b) Each facility under... technologies (BDT). The numerical emission limits in this standard are expressed in terms of total organic...

  12. 40 CFR 60.500 - Applicability and designation of affected facility.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Performance for Bulk Gasoline Terminals § 60.500 Applicability and designation of affected facility. (a) The... bulk gasoline terminal which deliver liquid product into gasoline tank trucks. (b) Each facility under... technologies (BDT). The numerical emission limits in this standard are expressed in terms of total organic...

  13. 43 CFR 3270.10 - What types of geothermal operations are governed by these utilization regulations?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... of geothermal resources. This includes: (1) Electrical generation facilities; (2) Direct use facilities; (3) Related utilization facility operations; (4) Actual and allocated well field production and injection; and (5) Related well field operations. (b) The utilization regulations in subparts 3270 through...

  14. 27 CFR 19.79 - Discontinuance of storage facilities.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Discontinuance of storage... Provisions Activities Not Subject to This Part § 19.79 Discontinuance of storage facilities. When the appropriate TTB officer finds that any facilities for the storage of spirits on bonded premises are unsafe or...

  15. 10 CFR 50.78 - Facility information and verification.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 1 2011-01-01 2011-01-01 false Facility information and verification. 50.78 Section 50.78 Energy NUCLEAR REGULATORY COMMISSION DOMESTIC LICENSING OF PRODUCTION AND UTILIZATION FACILITIES Us/iaea... International Atomic Energy Agency (IAEA) and take other action as necessary to implement the US/IAEA Safeguards...

  16. 10 CFR 50.78 - Facility information and verification.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 1 2010-01-01 2010-01-01 false Facility information and verification. 50.78 Section 50.78 Energy NUCLEAR REGULATORY COMMISSION DOMESTIC LICENSING OF PRODUCTION AND UTILIZATION FACILITIES Us/iaea... International Atomic Energy Agency (IAEA) and take other action as necessary to implement the US/IAEA Safeguards...

  17. 9 CFR 3.103 - Facilities, outdoor.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Administrator. The fence must be constructed so that it protects marine mammals by restricting animals and... effective natural barrier that restricts the marine mammals to the facility and restricts entry by animals... 9 Animals and Animal Products 1 2012-01-01 2012-01-01 false Facilities, outdoor. 3.103 Section 3...

  18. 9 CFR 3.103 - Facilities, outdoor.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Administrator. The fence must be constructed so that it protects marine mammals by restricting animals and... effective natural barrier that restricts the marine mammals to the facility and restricts entry by animals... 9 Animals and Animal Products 1 2013-01-01 2013-01-01 false Facilities, outdoor. 3.103 Section 3...

  19. 9 CFR 3.103 - Facilities, outdoor.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Administrator. The fence must be constructed so that it protects marine mammals by restricting animals and... effective natural barrier that restricts the marine mammals to the facility and restricts entry by animals... 9 Animals and Animal Products 1 2014-01-01 2014-01-01 false Facilities, outdoor. 3.103 Section 3...

  20. The CELSS Test Facility Project - An example of a CELSS flight experiment system

    NASA Technical Reports Server (NTRS)

    Macelroy, R. D.; Straight, C. L.

    1992-01-01

    The design of the facility is described in terms of its use as an investigation tool for evaluating crop growth in space with reference to required emerging technologies. NASA's CELSS Test Facility (CTF) is designed to permit the measurement of crop-plant productivity under microgravity conditions including biomass production, food production, water transpiration, and O2/CO2 exchanges. Crucial hardware tests and qualifications are identified to assure the operation of CTF technologies in space including the nutrient-delivery, water-condensation, and gas-liquid-mixing subsystems. The design concept and related scientific requirements are described and shown to provide microgravity crop research. The CTF is expected to provide data for plant research and for concepts for bioregenerative life-support systems for applications to Martian, lunar, and space-station missions.

  1. Impact of air pollution control costs on the cost and spatial arrangement of cellulosic biofuel production in the U.S.

    PubMed

    Murphy, Colin W; Parker, Nathan C

    2014-02-18

    Air pollution emissions regulation can affect the location, size, and technology choice of potential biofuel production facilities. Difficulty in obtaining air pollutant emission permits and the cost of air pollution control devices have been cited by some fuel producers as barriers to development. This paper expands on the Geospatial Bioenergy Systems Model (GBSM) to evaluate the effect of air pollution control costs on the availability, cost, and distribution of U.S. biofuel production by subjecting potential facility locations within U.S. Clean Air Act nonattainment areas, which exceed thresholds for healthy air quality, to additional costs. This paper compares three scenarios: one with air quality costs included, one without air quality costs, and one in which conversion facilities were prohibited in Clean Air Act nonattainment areas. While air quality regulation may substantially affect local decisions regarding siting or technology choices, their effect on the system as a whole is small. Most biofuel facilities are expected to be sited near to feedstock supplies, which are seldom in nonattainment areas. The average cost per unit of produced energy is less than 1% higher in the scenarios with air quality compliance costs than in scenarios without such costs. When facility construction is prohibited in nonattainment areas, the costs increase by slightly over 1%, due to increases in the distance feedstock is transported to facilities in attainment areas.

  2. Reinforced Plastic Composites Production: National Emission Standards for Hazardous Air Pollutants

    EPA Pesticide Factsheets

    National emissions standards for hazardous air pollutants for reinforced plastic composites production facilities. Regulates production and ancillary processes used to manufacture products with thermoset resins and gel coats.

  3. Insights into the transposable mobilome of Paracoccus spp. (Alphaproteobacteria).

    PubMed

    Dziewit, Lukasz; Baj, Jadwiga; Szuplewska, Magdalena; Maj, Anna; Tabin, Mateusz; Czyzkowska, Anna; Skrzypczyk, Grazyna; Adamczuk, Marcin; Sitarek, Tomasz; Stawinski, Piotr; Tudek, Agnieszka; Wanasz, Katarzyna; Wardal, Ewa; Piechucka, Ewa; Bartosik, Dariusz

    2012-01-01

    Several trap plasmids (enabling positive selection of transposition events) were used to identify a pool of functional transposable elements (TEs) residing in bacteria of the genus Paracoccus (Alphaproteobacteria). Complex analysis of 25 strains representing 20 species of this genus led to the capture and characterization of (i) 37 insertion sequences (ISs) representing 9 IS families (IS3, IS5, IS6, IS21, IS66, IS256, IS1182, IS1380 and IS1634), (ii) a composite transposon Tn6097 generated by two copies of the ISPfe2 (IS1634 family) containing two predicted genetic modules, involved in the arginine deiminase pathway and daunorubicin/doxorubicin resistance, (iii) 3 non-composite transposons of the Tn3 family, including Tn5393 carrying streptomycin resistance and (iv) a transposable genomic island TnPpa1 (45 kb). Some of the elements (e.g. Tn5393, Tn6097 and ISs of the IS903 group of the IS5 family) were shown to contain strong promoters able to drive transcription of genes placed downstream of the target site of transposition. Through the application of trap plasmid pCM132TC, containing a promoterless tetracycline resistance reporter gene, we identified five ways in which transposition can supply promoters to transcriptionally silent genes. Besides highlighting the diversity and specific features of several TEs, the analyses performed in this study have provided novel and interesting information on (i) the dynamics of the process of transposition (e.g. the unusually high frequency of transposition of TnPpa1) and (ii) structural changes in DNA mediated by transposition (e.g. the generation of large deletions in the recipient molecule upon transposition of ISPve1 of the IS21 family). We also demonstrated the great potential of TEs and transposition in the generation of diverse phenotypes as well as in the natural amplification and dissemination of genetic information (of adaptative value) by horizontal gene transfer, which is considered the driving force of bacterial evolution.

  4. Insights into the Transposable Mobilome of Paracoccus spp. (Alphaproteobacteria)

    PubMed Central

    Dziewit, Lukasz; Baj, Jadwiga; Szuplewska, Magdalena; Maj, Anna; Tabin, Mateusz; Czyzkowska, Anna; Skrzypczyk, Grazyna; Adamczuk, Marcin; Sitarek, Tomasz; Stawinski, Piotr; Tudek, Agnieszka; Wanasz, Katarzyna; Wardal, Ewa; Piechucka, Ewa; Bartosik, Dariusz

    2012-01-01

    Several trap plasmids (enabling positive selection of transposition events) were used to identify a pool of functional transposable elements (TEs) residing in bacteria of the genus Paracoccus (Alphaproteobacteria). Complex analysis of 25 strains representing 20 species of this genus led to the capture and characterization of (i) 37 insertion sequences (ISs) representing 9 IS families (IS3, IS5, IS6, IS21, IS66, IS256, IS1182, IS1380 and IS1634), (ii) a composite transposon Tn6097 generated by two copies of the ISPfe2 (IS1634 family) containing two predicted genetic modules, involved in the arginine deiminase pathway and daunorubicin/doxorubicin resistance, (iii) 3 non-composite transposons of the Tn3 family, including Tn5393 carrying streptomycin resistance and (iv) a transposable genomic island TnPpa1 (45 kb). Some of the elements (e.g. Tn5393, Tn6097 and ISs of the IS903 group of the IS5 family) were shown to contain strong promoters able to drive transcription of genes placed downstream of the target site of transposition. Through the application of trap plasmid pCM132TC, containing a promoterless tetracycline resistance reporter gene, we identified five ways in which transposition can supply promoters to transcriptionally silent genes. Besides highlighting the diversity and specific features of several TEs, the analyses performed in this study have provided novel and interesting information on (i) the dynamics of the process of transposition (e.g. the unusually high frequency of transposition of TnPpa1) and (ii) structural changes in DNA mediated by transposition (e.g. the generation of large deletions in the recipient molecule upon transposition of ISPve1 of the IS21 family). We also demonstrated the great potential of TEs and transposition in the generation of diverse phenotypes as well as in the natural amplification and dissemination of genetic information (of adaptative value) by horizontal gene transfer, which is considered the driving force of bacterial evolution. PMID:22359677

  5. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cozzi, A.; Johnson, F.

    Production of Mo-99 for medical isotope use is being investigated using dissolved low enriched uranium (LEU) fissioned using an accelerator driven process. With the production and separation of Mo-99, a low level waste stream will be generated. Since the production facility is a commercial endeavor, waste disposition paths normally available for federally generated radioactive waste may not be available. Disposal sites for commercially generated low level waste are available, and consideration to the waste acceptance criteria (WAC) of the disposal site should be integral in flowsheet development for the Mo-99 production. Pending implementation of the “Uranium Lease and Take-Back Programmore » for Irradiation for Production of Molybdenum-99 for Medical Use” as directed by the American Medical Isotopes Production Act of 2012, there are limited options for disposing of the waste generated by the production of Mo-99 using an accelerator. The commission of a trade study to assist in the determination of the most favorable balance of production throughput and waste management should be undertaken. The use of a waste broker during initial operations of a facility has several benefits that can offset the cost associated with using a subcontractor. As the facility matures, the development of in-house capabilities can be expanded to incrementally reduce the dependence on a subcontractor.« less

  6. New irradiation facilities for development of production methods of medical radionuclides at cyclotrons at Forschungszentrum Jülich

    NASA Astrophysics Data System (ADS)

    Spellerberg, S.; Scholten, B.; Spahn, I.; Felden, O.; Gebel, R.; Qaim, S. M.; Bai, M.; Neumaier, B.

    2017-05-01

    An essential basis for research and development work on radiopharmaceuticals is the efficient production of radionuclides of high quality. In this process research-oriented studies aiming for elucidation of biochemical processes require novel products. The radionuclide development at INM-5 entails basic research, e.g. the determination of nuclear reaction data, as well as technical aspects of practical production, such as high-current targetry, chemical separation, formulation and quality control. In this work developments, adaptation and optimization of irradiation facilities at the BC 1710, JULIC as Injector of COSY and COSY itself are summarized, which shall allow the extension of radionuclide production possibilities, aiming at innovations in medical applications.

  7. Development of a Medical Cyclotron Production Facility

    NASA Astrophysics Data System (ADS)

    Allen, Danny R.

    2003-08-01

    Development of a Cyclotron manufacturing facility begins with a business plan. Geographics, the size and activity of the medical community, the growth potential of the modality being served, and other business connections are all considered. This business used the customer base established by NuTech, Inc., an independent centralized nuclear pharmacy founded by Danny Allen. With two pharmacies in operation in Tyler and College Station and a customer base of 47 hospitals and clinics the existing delivery system and pharmacist staff is used for the cyclotron facility. We then added cyclotron products to contracts with these customers to guarantee a supply. We partnered with a company in the process of developing PET imaging centers. We then built an independent imaging center attached to the cyclotron facility to allow for the use of short-lived isotopes.

  8. Reducing Proliferation Rick Through Multinational Fuel Cycle Facilities

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Amanda Rynes

    2010-11-01

    With the prospect of rapid expansion of the nuclear energy industry and the ongoing concern over weapons proliferation, there is a growing need for a viable alternative to traditional nation-based fuel production facilities. While some in the international community remain apprehensive, the advantages of multinational fuel cycle facilities are becoming increasingly apparent, with states on both sides of the supply chain able to garner the security and financial benefits of such facilities. Proliferation risk is minimized by eliminating the need of states to establish indigenous fuel production capabilities and the concept's structure provides an additional internationally monitored barrier against themore » misuse or diversion of nuclear materials. This article gives a brief description of the arguments for and against the implementation of a complete multinational fuel cycle.« less

  9. Baseline process description for simulating plutonium oxide production for precalc project

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pike, J. A.

    Savannah River National Laboratory (SRNL) started a multi-year project, the PreCalc Project, to develop a computational simulation of a plutonium oxide (PuO 2) production facility with the objective to study the fundamental relationships between morphological and physicochemical properties. This report provides a detailed baseline process description to be used by SRNL personnel and collaborators to facilitate the initial design and construction of the simulation. The PreCalc Project team selected the HB-Line Plutonium Finishing Facility as the basis for a nominal baseline process since the facility is operational and significant model validation data can be obtained. The process boundary as wellmore » as process and facility design details necessary for multi-scale, multi-physics models are provided.« less

  10. The National Shipbuilding Research Program. National Workshop (4th) on Human Resource Innovation in Shipbuilding and Ship Repair

    DTIC Science & Technology

    1995-11-01

    SHIP PRODUCTION COMMITTEE FACILITIES AND ENVIRONMENTAL EFFECTS SURFACE PREPARATION AND COATINGS DESIGN/PRODUCTION INTEGRATION HUMAN RESOURCE...we’re all about. 2 Exhibit 1 NATIONAL SHIPBUILDING RESEARCH PROGRAM RESEARCH PANELS SP-1 Facilities and Environmental Effects SP-3 Surface... effectively compete in the international commercial shipbuilding market. On November 30,1993, President Clinton signed into law the National

  11. 16 CFR Figures 3 and 4 to Part 1204 - High Voltage Test Facility and Antenna System Test Setup

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 16 Commercial Practices 2 2012-01-01 2012-01-01 false High Voltage Test Facility and Antenna System Test Setup 3 Figures 3 and 4 to Part 1204 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION CONSUMER PRODUCT SAFETY ACT REGULATIONS SAFETY STANDARD FOR OMNIDIRECTIONAL CITIZENS BAND BASE STATION ANTENNAS Pt. 1204, Figs. 3, 4 Figures 3 and 4...

  12. Data reduction complex analog-to-digital data processing requirements for onsite test facilities

    NASA Technical Reports Server (NTRS)

    Debbrecht, J. D.

    1976-01-01

    The analog to digital processing requirements of onsite test facilities are described. The source and medium of all input data to the Data Reduction Complex (DRC) and the destination and medium of all output products of the analog-to-digital processing are identified. Additionally, preliminary input and output data formats are presented along with the planned use of the output products.

  13. Mapping the Risks. Assessing the Homeland Security Implications of Publicly Available Geospatial Information

    DTIC Science & Technology

    2004-01-01

    Defense Nuclear Facilities Safety Board 1 0.2 Export-Import Bank 1 0.2 National Archives and Records Administration 1 0.2 Supreme Court of the United...Agency Commodity Futures Trading Commission Consumer Product Safety Commission Defense Nuclear Facilities Safety Board Environmental Protection Agency...Intelligence www.cia.gov Defense Nuclear Facilities Safety Board Defense Nuclear Facilities Safety Board www.dnfsb.gov Department of

  14. Pion Inelastic Scattering to the First Three Excited States of Lithium-6.

    DTIC Science & Technology

    1984-12-01

    and Spectrometer system at the Clinton P. Anderson Meson Physics Facility, differential cross sections were measured for n+ inelastic scattering to the...Professor: C. Fred Moore Using the Energetic Pion Channel and Spectrometer system at the Clinton P. Anderson Meson Physics Facility, differential cross...due to the construction and subsequent operation of three meson production facilities: the Los Alamos Meson Physics Facility (LAMPF) in the United

  15. Electric power generation using geothermal brine resources for a proof of concept facility

    NASA Technical Reports Server (NTRS)

    Hankin, J. W.

    1974-01-01

    An exploratory systems study of a geothermal proof-of-concept facility is being conducted. This study is the initial phase (Phase 0) of a project to establish the technical and economic feasibility of using hot brine resources for electric power production and other industrial applications. Phase 0 includes the conceptual design of an experimental test-bed facility and a 10-MWe power generating facility.

  16. 10 CFR 451.4 - What is a qualified renewable energy facility.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 3 2013-01-01 2013-01-01 false What is a qualified renewable energy facility. 451.4 Section 451.4 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION RENEWABLE ENERGY PRODUCTION INCENTIVES § 451.4 What is a qualified renewable energy facility. In order to qualify for an incentive payment under...

  17. 78 FR 52971 - Notice of Lodging of Consent Decree Pursuant to the Clean Air Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-27

    ... Defendant's coke production facilities located at 400 East Winchester Avenue in Ashland, Kentucky. The Defendant ceased operations at the coke facilities on June 21, 2011. Under this settlement between the... coke facilities are no longer in operation, the Defendant is not required, under this Consent Decree...

  18. NRL Review - 2009

    DTIC Science & Technology

    2009-01-01

    for a fundamental physical understanding of electronic properties . The Materials Processing Facility includes appa- ratuses for powder production by...situ. Facilities to process powder into bulk specimens by hot and cold isostatic pressing permit a variety of consolidation possibilities. The iso...Synthesis/ Property Measurement Facility has special emphasis on polymers, surface-film processing , and directed self-assembly. The Chemical Vapor

  19. 10 CFR 451.4 - What is a qualified renewable energy facility.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 3 2010-01-01 2010-01-01 false What is a qualified renewable energy facility. 451.4 Section 451.4 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION RENEWABLE ENERGY PRODUCTION INCENTIVES § 451.4 What is a qualified renewable energy facility. In order to qualify for an incentive payment under...

  20. 10 CFR 451.4 - What is a qualified renewable energy facility.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 3 2011-01-01 2011-01-01 false What is a qualified renewable energy facility. 451.4 Section 451.4 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION RENEWABLE ENERGY PRODUCTION INCENTIVES § 451.4 What is a qualified renewable energy facility. In order to qualify for an incentive payment under...

  1. A laboratory facility for research on wind-driven rain intrusion in building envelope assemblies

    Treesearch

    Samuel V. Glass

    2010-01-01

    Moisture management is critical for durable, energy-efficient buildings. To address the need for research on wind-driven rain intrusion in wall assemblies, the U.S. Forest Products Laboratory is developing a new facility. This paper describes the underlying principle of this facility and its capabilities.

  2. New Spaces for Learning: Designing College Facilities to Utilize Instructional Aids and Media. Revised.

    ERIC Educational Resources Information Center

    Hauf, Harold D.; And Others

    Colleges need appropriate large group instructional facilities for effective and efficient use of instructional aids and media. A well planned system of facilities must provide space for learning; production, origination, and support; storage and retrieval. Design begins with a building plan--a statement, made jointly by the administrator and…

  3. 40 CFR 63.2334 - Am I subject to this subpart?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...) Oil and natural gas production field facilities, as the term “facility” is defined in § 63.761 of subpart HH. (2) Natural gas transmission and storage facilities, as the term “facility” is defined in § 63... distribution operations located at research and development facilities, consistent with section 112(c)(7) of...

  4. 9 CFR 590.506 - Candling and transfer-room facilities and equipment.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Candling and transfer-room facilities... INSPECTION ACT) Sanitary, Processing, and Facility Requirements § 590.506 Candling and transfer-room... containers are furnished daily. (h) Shell egg conveyors shall be constructed so that they can be thoroughly...

  5. 10 CFR 451.4 - What is a qualified renewable energy facility.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 3 2014-01-01 2014-01-01 false What is a qualified renewable energy facility. 451.4 Section 451.4 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION RENEWABLE ENERGY PRODUCTION INCENTIVES § 451.4 What is a qualified renewable energy facility. In order to qualify for an incentive payment under...

  6. 10 CFR 451.4 - What is a qualified renewable energy facility.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 3 2012-01-01 2012-01-01 false What is a qualified renewable energy facility. 451.4 Section 451.4 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION RENEWABLE ENERGY PRODUCTION INCENTIVES § 451.4 What is a qualified renewable energy facility. In order to qualify for an incentive payment under...

  7. The Commuting Student Study, Report IV: Food Facilities.

    ERIC Educational Resources Information Center

    Williamson, W. J.; And Others

    This report presents a detailed analysis of the food facilities at the University of Alberta. Emphasis is placed on the three main supplies of food: the peak production of cafeterias at meal times, the snack facilities, and vending machines. Study results indicate: (1) extensive use of the students' union building cafeterias; (2) reported use of…

  8. Development of a High Volume Capable Process to Manufacture High Performance Photovoltaic Cells: Cooperative Research and Development Final Report, CRADA Number CRD-08-322

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Geisz, J. F.

    2012-11-01

    The intent of the work is for RFMD and NREL to cooperate in the development of a commercially viable and high volume capable process to manufacture high performance photovoltaic cells, based on inverted metamorphic (IMM) GaAs technology. The successful execution of the agreement will result in the production of a PV cell using technology that is capable of conversion efficiency at par with the market at the time of release (reference 2009: 37-38%), using RFMD's production facilities. The CRADA work has been divided into three phases: (1) a foundation phase where the teams will demonstrate the manufacturing of a basicmore » PV cell at RFMD's production facilities; (2) a technology demonstration phase where the teams will demonstrate the manufacturing of prototype PV cells using IMM technology at RFMD's production facilities, and; (3) a production readiness phase where the teams will demonstrate the capability to manufacture PV cells using IMM technology with high yields, high reliability, high reproducibility and low cost.« less

  9. The ASTROCULTURE Facility

    NASA Technical Reports Server (NTRS)

    1998-01-01

    Research with plants in microgravity offers many exciting opportunities to gain new insights and could improve products on Earth ranging from crop production to fragrances and food flavorings. The ASTROCULTURE facility is a lead commercial facility for plant growth and plant research in microgravity and was developed by the Wisconsin Center for Space Automation and Robotics (WSCAR), a NASA Commercial Space Center. On STS-95 it will support research that could help improve crop development leading to plants that are more disease resistant or have a higher yield and provide data on the production of plant essential oils---oils that contain the essence of the plant and provide both fragrance and flavoring. On STS-95, a flowering plant will be grown in ASTROCULTURE and samples taken using a method developed by the industry partner for this investigation. On Earth, the samples will be analyzed by gas chromatography/mass spectrometry and the data used to evaluate both the production of fragrant oils in microgravity and in the development of one or more products. The ASTROCULTURE payload uses these pourous tubes with precise pressure sensing and control for fluid delivery to the plant root tray.

  10. Purdue University National Biomedical Tracer Facility: Project definition phase. Final report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Green, M.A.

    The proposed National Biomedical Tracer Facility (NBTF) will house a high-current accelerator dedicated to production of short-lived radionuclides for biomedical and scientific research. The NBTF will play a vital role in repairing and maintaining the United States` research infrastructure for generation of essential accelerator-based radioisotopes. If properly designed and managed, the NBTF should also achieve international recognition as a Center-of-Excellence for research on radioisotope production methods and for associated education and training. The current report documents the results of a DOE-funded NBTF Project Definition Phase study carried out to better define the technical feasibility and projected costs of establishing andmore » operating the NBTF. This report provides an overview of recommended Facility Design and Specifications, including Accelerator Design, Building Design, and the associated Construction Cost Estimates and Schedule. It is recommended that the NBTF be established as an integrated, comprehensive facility for meeting the diverse production, research, and educational missions set forth in previous documents. Based on an analysis of the projected production demands that will be placed on the NBTF, it appears that a 70 MeV, 1 mA, negative ion cyclotron will offer a good balance between production capabilities and the costs of accelerator purchase and operation. A preliminary architectural plan is presented for a facility designed specifically to fulfill the functions of the NBTF in a cost-effective manner. This report also presents a detailed analysis of the Required Federal State, and Local Permits that may be needed to establish the NBTF, along with schedules and cost estimates for obtaining these permits. The Handling, Storage, and Disposal of Radioactive Waste will pose some significant challenges in the operation of the NBTF, but at this stage of planning the associated problems do not appear to be prohibitive.« less

  11. Risks to health care workers from nano-enabled medical products.

    PubMed

    Murashov, Vladimir; Howard, John

    2015-01-01

    Nanotechnology is rapidly expanding into the health care industry. However, occupational safety and health risks of nano-enabled medical products have not been thoroughly assessed. This manuscript highlights occupational risk mitigation practices for nano-enabled medical products throughout their life cycle for all major workplace settings including (1) medical research laboratories, (2) pharmaceutical manufacturing facilities, (3) clinical dispensing pharmacies, (4) health care delivery facilities, (5) home health care, (6) health care support, and (7) medical waste management. It further identifies critical research needs for ensuring worker protection in the health care industry.

  12. The Purpose of Mathematical Programming is Insight, Not Numbers

    DTIC Science & Technology

    1976-06-01

    consumer products manufacturer. fN mnr.m t« m nih iwtiN "« mtme* a D y 1 BUt’CIHCEll ’"’•’laiHW... Udhi.’dMIH« ■» B r [?■ SEP 21 1D?G...summarizes my experience with auxiliary models in the context of a facility location study carried out recently for a consumer pro- ducts manufacturer...APPLICATION IN THE CONTEXT OF FACILITY LOCATION A consumer products manufacturer has a single plant in California making a range of products

  13. Pilot production & commercialization of LAPPD ™

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Minot, Michael J.; Bennis, Daniel C.; Bond, Justin L.

    We present a progress update on plans to establish pilot production and commercialization of Large Area (400 cm2) Picosecond Photodetector (LAPPD™). Steps being taken to commercialize this MCP and LAPPD™ technology and begin tile pilot production are presented including (1) the manufacture of 203 mm×203 mm borosilicate glass capillary arrays (GCAs), (2) optimization of MCP performance and creation of an ALD coating facility to manufacture MCPs and (3) design, construction and commissioning of UHV tile integration and sealing facility to produce LAPPDs. Taken together these plans provide a “pathway toward commercialization”.

  14. 48 CFR 23.704 - Application to Government-owned or -leased facilities.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... TECHNOLOGIES, OCCUPATIONAL SAFETY, AND DRUG-FREE WORKPLACE Contracting for Environmentally Preferable Products... and contracts for support services at a Government-owned or -operated facility include provisions that...

  15. Comparison of methane emission estimates from multiple measurement techniques at natural gas production pads

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bell, Clay Samuel; Vaughn, Timothy L.; Zimmerle, Daniel

    This study presents the results of a campaign that estimated methane emissions at 268 gas production facilities in the Fayetteville shale gas play using onsite measurements (261 facilities) and two downwind methods - the dual tracer flux ratio method (Tracer Facility Estimate - TFE, 17 facilities) and the EPA Other Test Method 33a (OTM33A Facility Estimate - OFE, 50 facilities). A study onsite estimate (SOE) for each facility was developed by combining direct measurements and simulation of unmeasured emission sources, using operator activity data and emission data from literature. The SOE spans 0-403 kg/h and simulated methane emissions from liquidmore » unloadings account for 88% of total emissions estimated by the SOE, with 76% (95% CI [51%-92%]) contributed by liquid unloading at two facilities. TFE and SOE show overlapping 95% CI between individual estimates at 15 of 16 (94%) facilities where the measurements were paired, while OFE and SOE show overlapping 95% CI between individual estimates at 28 of 43 (65%) facilities. However, variance-weighted least-squares (VWLS) regressions performed on sets of paired estimates indicate statistically significant differences between methods. The SOE represents a lower bound of emissions at facilities where onsite direct measurements of continuously emitting sources are the primary contributor to the SOE, a sub-selection of facilities which minimizes expected inter-method differences for intermittent pneumatic controllers and the impact of episodically-emitting unloadings. At 9 such facilities, VWLS indicates that TFE estimates systematically higher emissions than SOE (TFE-to-SOE ratio = 1.6, 95% CI [1.2 to 2.1]). At 20 such facilities, VWLS indicates that OFE estimates systematically lower emissions than SOE (OFE-to-SOE ratio of 0.41 [0.26 to 0.90]). Given that SOE at these facilities is a lower limit on emissions, these results indicate that OFE is likely a less accurate method than SOE or TFE for this type of facility.« less

  16. Comparison of methane emission estimates from multiple measurement techniques at natural gas production pads

    DOE PAGES

    Bell, Clay Samuel; Vaughn, Timothy L.; Zimmerle, Daniel; ...

    2017-02-09

    This study presents the results of a campaign that estimated methane emissions at 268 gas production facilities in the Fayetteville shale gas play using onsite measurements (261 facilities) and two downwind methods - the dual tracer flux ratio method (Tracer Facility Estimate - TFE, 17 facilities) and the EPA Other Test Method 33a (OTM33A Facility Estimate - OFE, 50 facilities). A study onsite estimate (SOE) for each facility was developed by combining direct measurements and simulation of unmeasured emission sources, using operator activity data and emission data from literature. The SOE spans 0-403 kg/h and simulated methane emissions from liquidmore » unloadings account for 88% of total emissions estimated by the SOE, with 76% (95% CI [51%-92%]) contributed by liquid unloading at two facilities. TFE and SOE show overlapping 95% CI between individual estimates at 15 of 16 (94%) facilities where the measurements were paired, while OFE and SOE show overlapping 95% CI between individual estimates at 28 of 43 (65%) facilities. However, variance-weighted least-squares (VWLS) regressions performed on sets of paired estimates indicate statistically significant differences between methods. The SOE represents a lower bound of emissions at facilities where onsite direct measurements of continuously emitting sources are the primary contributor to the SOE, a sub-selection of facilities which minimizes expected inter-method differences for intermittent pneumatic controllers and the impact of episodically-emitting unloadings. At 9 such facilities, VWLS indicates that TFE estimates systematically higher emissions than SOE (TFE-to-SOE ratio = 1.6, 95% CI [1.2 to 2.1]). At 20 such facilities, VWLS indicates that OFE estimates systematically lower emissions than SOE (OFE-to-SOE ratio of 0.41 [0.26 to 0.90]). Given that SOE at these facilities is a lower limit on emissions, these results indicate that OFE is likely a less accurate method than SOE or TFE for this type of facility.« less

  17. Measurements and calculations of air activation in the NuMI neutrino production facility at Fermilab with the 120-GeV proton beam on target

    NASA Astrophysics Data System (ADS)

    Rakhno, I. L.; Hylen, J.; Kasper, P.; Mokhov, N. V.; Quinn, M.; Striganov, S. I.; Vaziri, K.

    2018-01-01

    Measurements and calculations of the air activation at a high-energy proton accelerator are described. The quantity of radionuclides released outdoors depends on operation scenarios including details of the air exchange inside the facility. To improve the prediction of the air activation levels, the MARS15 Monte Carlo code radionuclide production model was modified to be used for these studies. Measurements were done to benchmark the new model and verify its use in optimization studies for the new DUNE experiment at the Long Baseline Neutrino Facility (LBNF) at Fermilab. The measured production rates for the most important radionuclides - 11C, 13N, 15O and 41Ar - are in a good agreement with those calculated with the improved MARS15 code.

  18. Commissioning of a CERN Production and Analysis Facility Based on xrootd

    NASA Astrophysics Data System (ADS)

    Campana, Simone; van der Ster, Daniel C.; Di Girolamo, Alessandro; Peters, Andreas J.; Duellmann, Dirk; Coelho Dos Santos, Miguel; Iven, Jan; Bell, Tim

    2011-12-01

    The CERN facility hosts the Tier-0 of the four LHC experiments, but as part of WLCG it also offers a platform for production activities and user analysis. The CERN CASTOR storage technology has been extensively tested and utilized for LHC data recording and exporting to external sites according to experiments computing model. On the other hand, to accommodate Grid data processing activities and, more importantly, chaotic user analysis, it was realized that additional functionality was needed including a different throttling mechanism for file access. This paper will describe the xroot-based CERN production and analysis facility for the ATLAS experiment and in particular the experiment use case and data access scenario, the xrootd redirector setup on top of the CASTOR storage system, the commissioning of the system and real life experience for data processing and data analysis.

  19. Mitigation of laser damage on National Ignition Facility optics in volume production

    NASA Astrophysics Data System (ADS)

    Folta, James; Nostrand, Mike; Honig, John; Wong, Nan; Ravizza, Frank; Geraghty, Paul; Taranowski, Mike; Johnson, Gary; Larkin, Glenn; Ravizza, Doug; Peterson, John; Welday, Brian; Wegner, Paul

    2013-12-01

    The National Ignition Facility has recently achieved the milestone of delivering over 1.8 MJ and 500 TW of 351 nm laser energy and power on target, which required average fluences up to 9 J/cm2 (3 ns equivalent) in the final optics system. Commercial fused silica laser-grade UV optics typically have a maximum operating threshold of 5 J/cm2. We have developed an optics recycling process which enables NIF to operate above the laser damage initiation and growth thresholds. We previously reported a method to mitigate laser damage with laser ablation of the damage site to leave benign cone shaped pits. We have since developed a production facility with four mitigation systems capable of performing the mitigation protocols on full-sized (430 mm) optics in volume production. We have successfully repaired over 700 NIF optics (unique serial numbers), some of which have been recycled as many as 11 times. We describe the mitigation systems, the optics recycle loop process, and optics recycle production data.

  20. The BioDyn facility on ISS: Advancing biomaterial production in microgravity for commercial applications

    NASA Astrophysics Data System (ADS)

    Myers, Niki; Wessling, Francis; Deuser, Mark; Anderson, C. D.; Lewis, Marian

    1999-01-01

    The primary goals of the BioDyn program are to foster use of the microgravity environment for commercial production of bio-materials from cells, and to develop services and processes for obtaining these materials through space processing. The scope of products includes commercial bio-molecules such as cytokines, other cell growth regulatory proteins, hormones, monoclonal antibodies and enzymes; transplantable cells or tissues which can be improved by low-G processes, or which cannot be obtained through standard processes in earth gravity; agriculture biotechnology products from plant cells; microencapsulation for diabetes treatment; and factors regulating cellular aging. To facilitate BioDyn's commercial science driven goals, hardware designed for ISS incorporates the flexibility for interchange between the different ISS facilities including the glovebox, various thermal units and centrifuges. By providing a permanent research facility, ISS is the critical space-based platform required by scientists for carrying out the long-term experiments necessary for developing bio-molecules and tissues using several cell culture modalities including suspension and anchorage-dependent cell types.

  1. NRU is onstream successfully at Block 31

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Looney, S.K.; Price, B.C.; Wilson, C.A.

    1986-12-17

    A nitrogen rejection facility, designed and fabricated by Koch Process Systems Inc., has exceeded design capacity and product purity specifications on Block 31 field about 30 miles south of Odessa, Tex. The unit is currently processing approximately 65 MMscfd of oil-associated gas; producing 21 MMscfd nitrogen, 32 MMscfd fuel gas, and 320,000 gal/day ethane-plus product. The startup of this nitrogen rejection facility represents the first facility for handling a feed with such a wide variation in composition. The process worked according to design and has met or exceeded product criteria. The plant is currently processing 10% over design at 78more » MMscfd (70 MMscfd net raw feed) and producing 330,000 gal/day of NGL's, with an ethane recovery of 88%. As with most startups, the main problems were with the rotating equipment items, especially the expander/compressor units. The NRF is providing a reliable source of fuel and should increase plant production and field life.« less

  2. The Establishment of a New Friction Stir Welding Process Development Facility at NASA/MSFC

    NASA Technical Reports Server (NTRS)

    Carter, Robert W.

    2009-01-01

    Full-scale weld process development is being performed at MSFC to develop the tools, fixtures, and facilities necessary for Ares I production. Full scale development in-house at MSFC fosters technical acuity within the NASA engineering community, and allows engineers to identify and correct tooling and equipment shortcomings before they become problems on the production floor. Finally, while the new weld process development facility is currently being outfitted in support of Ares I development, it has been established to support all future Constellation Program needs. In particular, both the RWT and VWT were sized with the larger Ares V hardware in mind.

  3. Automated System Calibration and Verification of the Position Measurements for the Los Alamos Isotope Production Facility and the Switchyard Kicker Facilities

    NASA Astrophysics Data System (ADS)

    Barr, D.; Gilpatrick, J. D.; Martinez, D.; Shurter, R. B.

    2004-11-01

    The Los Alamos Neutron Science Center (LANSCE) facility at Los Alamos National Laboratory has constructed both an Isotope Production Facility (IPF) and a Switchyard Kicker (XDK) as additions to the H+ and H- accelerator. These additions contain eleven Beam Position Monitors (BPMs) that measure the beam's position throughout the transport. The analog electronics within each processing module determines the beam position using the log-ratio technique. For system reliability, calibrations compensate for various temperature drifts and other imperfections in the processing electronics components. Additionally, verifications are periodically implemented by a PC running a National Instruments LabVIEW virtual instrument (VI) to verify continued system and cable integrity. The VI communicates with the processor cards via a PCI/MXI-3 VXI-crate communication module. Previously, accelerator operators performed BPM system calibrations typically once per day while beam was explicitly turned off. One of this new measurement system's unique achievements is its automated calibration and verification capability. Taking advantage of the pulsed nature of the LANSCE-facility beams, the integrated electronics hardware and VI perform calibration and verification operations between beam pulses without interrupting production beam delivery. The design, construction, and performance results of the automated calibration and verification portion of this position measurement system will be the topic of this paper.

  4. Before You Buy.

    ERIC Educational Resources Information Center

    Milshtein, Amy

    1998-01-01

    Discusses how to avoid costly mistakes when buying facility-management software. Provides answers to questions buyers should ask before committing funds to a particular program. Selected facility-management software companies and product profiles are highlighted. (GR)

  5. Seeing the Supplier Light.

    ERIC Educational Resources Information Center

    May, Abigail, Ed.

    1998-01-01

    Discusses buying building products from vendors and how to make the job more productive and beneficial for the facilities manager. Examines building/vendor relationships, establishing product knowledge, and using effective communication. (GR)

  6. Characterization of exposure to silver nanoparticles in a manufacturing facility

    NASA Astrophysics Data System (ADS)

    Park, Junsu; Kwak, Byoung Kyu; Bae, Eunjoo; Lee, Jeongjin; Kim, Younghun; Choi, Kyunghee; Yi, Jongheop

    2009-10-01

    An assessment of the extent of exposure to nanomaterials in the workplace will be helpful in improving the occupational safety of workers. It is essential that the exposure data in the workplace are concerned with risk management to evaluate and reduce worker exposure. In a manufacturing facility dealing with nanomaterials, some exposure data for gas-phase reactions are available, but much less information is available regarding liquid-phase reactions. Although the potential for inhaling nanomaterials in a liquid-phase process is less than that for gas-phase, the risks of exposure during wet-chemistry processes are not negligible. In this study, we monitored and analyzed the exposure characteristics of silver nanoparticles during a liquid-phase process in a commercial production facility. Based on the measured exposure data, the source of Ag nanoparticles emitted during the production processes was indentified and a mechanism for the growth of Ag nanoparticle released is proposed. The data reported in this study could be used to establish occupational safety guidelines in the nanotechnology workplace, especially in a liquid-phase production facility.

  7. Understanding facilities design parameters for a remanufacturing system

    NASA Astrophysics Data System (ADS)

    Topcu, Aysegul; Cullinane, Thomas

    2005-11-01

    Remanufacturing is rapidly becoming a very important element in the economies of the world. Products such as washing machines, clothes driers, automobile parts, cell phones and a wide range of consumer durable goods are being reclaimed and sent through processes that restore these products to levels of operating performance that are as good or better than their new product performance. The operations involved in the remanufacturing process add several new dimensions to the work that must be performed. Disassembly is an operation that rarely appears on the operations chart of a typical production facility. The inspection and test functions in remanufacturing most often involve several more tasks than those involved in the first time manufacturing cycle. A close evaluation of most any remanufacturing operation reveals several points in the process in which parts must be cleaned, tested and stored. Although several researchers have focused their work on optimizing the disassembly function and the inspection, test and store functions, very little research has been devoted to studying the impact of the facilities design on the effectiveness of the remanufacturing process. The purpose of this paper will be to delineate the differences between first time manufacturing operations and remanufacturing operations for durable goods and to identify the features of the facilities design that must be considered if the remanufacturing operations are to be effective.

  8. Accelerator Production of Isotopes for Medical Use

    NASA Astrophysics Data System (ADS)

    Lapi, Suzanne

    2014-03-01

    The increase in use of radioisotopes for medical imaging and therapy has led to the development of novel routes of isotope production. For example, the production and purification of longer-lived position emitting radiometals has been explored to allow for nuclear imaging agents based on peptides, antibodies and nanoparticles. These isotopes (64Cu, 89Zr, 86Y) are typically produced via irradiation of solid targets on smaller medical cyclotrons at dedicated facilities. Recently, isotope harvesting from heavy ion accelerator facilities has also been suggested. The Facility for Rare Isotope Beams (FRIB) will be a new national user facility for nuclear science to be completed in 2020. Radioisotopes could be produced by dedicated runs by primary users or may be collected synergistically from the water in cooling-loops for the primary beam dump that cycle the water at flow rates in excess of hundreds of gallons per minute. A liquid water target system for harvesting radioisotopes at the National Superconducting Cyclotron Laboratory (NSCL) was designed and constructed as the initial step in proof-of-principle experiments to harvest useful radioisotopes in this manner. This talk will provide an overview of isotope production using both dedicated machines and harvesting from larger accelerators typically used for nuclear physics. Funding from Department of Energy under DESC0007352 and DESC0006862.

  9. Food Waste to Energy: How Six Water Resource Recovery ...

    EPA Pesticide Factsheets

    Water Resource Recovery Facilities (WRRFs) with anaerobic digestion have been harnessing biogas for heat and power since at least the 1920’s. A few are approaching “energy neutrality” and some are becoming “energy positive” through a combination of energy efficiency measures and the addition of outside organic wastes. Enhancing biogas production by adding fats, oil and grease (FOG) to digesters has become a familiar practice. Less widespread is the addition of other types of food waste, ranging from municipally collected food scraps to the byproducts of food processing facilities and agricultural production. Co-digesting with food waste, however, is becoming more common. As energy prices rise and as tighter regulations increase the cost of compliance, WRRFs across the county are tapping excess capacity while tempering rates. This report presents the co-digestion practices, performance, and the experiences of six such WRRFs. The report describes the types of food waste co-digested and the strategies--specifically, the tools, timing, and partnerships--employed to manage the material. Additionally, the report describes how the facilities manage wastewater solids, providing information about power production, biosolids use, and program costs. This product is intended to describe the available infrastructure for energy recovery from co-digestion of food waste and wastewater treatment facilities.

  10. Evaluating the relative impacts of operational and financial factors on the competitiveness of an algal biofuel production facility.

    PubMed

    Hise, Adam M; Characklis, Gregory W; Kern, Jordan; Gerlach, Robin; Viamajala, Sridhar; Gardner, Robert D; Vadlamani, Agasteswar

    2016-11-01

    Algal biofuels are becoming more economically competitive due to technological advances and government subsidies offering tax benefits and lower cost financing. These factors are linked, however, as the value of technical advances is affected by modeling assumptions regarding the growth conditions, process design, and financing of the production facility into which novel techniques are incorporated. Two such techniques, related to algal growth and dewatering, are evaluated in representative operating and financing scenarios using an integrated techno-economic model. Results suggest that these techniques can be valuable under specified conditions, but also that investment subsidies influence cost competitive facility design by incentivizing development of more capital intensive facilities (e.g., favoring hydrothermal liquefaction over transesterification-based facilities). Evaluating novel techniques under a variety of operational and financial scenarios highlights the set of site-specific conditions in which technical advances are most valuable, while also demonstrating the influence of subsidies linked to capital intensity. Copyright © 2016 Elsevier Ltd. All rights reserved.

  11. Identification of potential recovery facilities for designing a reverse supply chain network using physical programming

    NASA Astrophysics Data System (ADS)

    Pochampally, Kishore K.; Gupta, Surendra M.; Kamarthi, Sagar V.

    2004-02-01

    Although there are many quantitative models in the literature to design a reverse supply chain, every model assumes that all the recovery facilities that are engaged in the supply chain have enough potential to efficiently re-process the incoming used products. Motivated by the risk of re-processing used products in facilities of insufficient potentiality, this paper proposes a method to identify potential facilities in a set of candidate recovery facilities operating in a region where a reverse supply chain is to be established. In this paper, the problem is solved using a newly developed method called physical programming. The most significant advantage of using physical programming is that it allows a decision maker to express his preferences for values of criteria (for comparing the alternatives), not in the traditional form of weights but in terms of ranges of different degrees of desirability, such as ideal range, desirable range, highly desirable range, undesirable range, and unacceptable range. A numerical example is considered to illustrate the proposed method.

  12. Data Sharing Report Characterization of Isotope Row Facilities Oak Ridge National Laboratory Oak Ridge TN

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Weaver, Phyllis C.

    The U.S. Department of Energy (DOE) Oak Ridge Office of Environmental Management (EM-OR) requested that Oak Ridge Associated Universities (ORAU), working under the Oak Ridge Institute for Science and Education (ORISE) contract, provide technical and independent waste management planning support using funds provided by the American Recovery and Reinvestment Act (ARRA). Specifically, DOE EM-OR requested ORAU to plan and implement a survey approach, focused on characterizing the Isotope Row Facilities located at the Oak Ridge National Laboratory (ORNL) for future determination of an appropriate disposition pathway for building debris and systems, should the buildings be demolished. The characterization effort wasmore » designed to identify and quantify radiological and chemical contamination associated with building structures and process systems. The Isotope Row Facilities discussed in this report include Bldgs. 3030, 3031, 3032, 3033, 3033A, 3034, 3036, 3093, and 3118, and are located in the northeast quadrant of the main ORNL campus area, between Hillside and Central Avenues. Construction of the isotope production facilities was initiated in the late 1940s, with the exception of Bldgs. 3033A and 3118, which were enclosed in the early 1960s. The Isotope Row facilities were intended for the purpose of light industrial use for the processing, assemblage, and storage of radionuclides used for a variety of applications (ORNL 1952 and ORAU 2013). The Isotope Row Facilities provided laboratory and support services as part of the Isotopes Production and Distribution Program until 1989 when DOE mandated their shutdown (ORNL 1990). These facilities performed diverse research and developmental experiments in support of isotopes production. As a result of the many years of operations, various projects, and final cessation of operations, production was followed by inclusion into the surveillance and maintenance (S&M) project for eventual decontamination and decommissioning (D&D). The process for D&D and final dismantlement of facilities requires that the known contaminants of concern (COCs) be evaluated and quantified and to identify and quantify any additional contaminants in order to satisfy the waste acceptance criteria requirements for the desired disposal pathway. Known facility contaminants include, but are not limited to, asbestos-containing material (ACM), radiological contaminants, and chemical contaminants including polychlorinated biphenyls (PCBs) and metals.« less

  13. Characterization of Spatial Impact of Particles Emitted from a Cement Material Production Facility on Outdoor Particle Deposition in the Surrounding Community.

    PubMed

    Yu, Chang Ho; Fan, Zhihua Tina; McCandlish, Elizabeth; Stern, Alan H; Lioy, Paul J

    2011-10-01

    The objective of this study was to estimate the contribution of a facility that processes steel production slag into raw material for cement production to local outdoor particle deposition in Camden, NJ. A dry deposition sampler that can house four 37-mm quartz fiber filters was developed and used for the collection of atmospheric particle deposits. Two rounds of particle collection (3-4 weeks each) were conducted in 8-11 locations 200-800 m downwind of the facility. Background samples were concurrently collected in a remote area located ∼2 km upwind from the facility. In addition, duplicate surface wipe samples were collected side-by-side from each of the 13 locations within the same sampling area during the first deposition sampling period. One composite source material sample was also collected from a pile stored in the facility. Both the bulk of the source material and the <38 μm fraction subsample were analyzed to obtain the elemental source profile. The particle deposition flux in the study area was higher (24-83 mg/m 2 ·day) than at the background sites (13-17 mg/m 2 ·day). The concentration of Ca, a major element in the cement source production material, was found to exponentially decrease with increasing downwind distance from the facility (P < 0.05). The ratio of Ca/Al, an indicator of Ca enrichment due to anthropogenic sources in a given sample, showed a similar trend. These observations suggest a significant contribution of the facility to the local particle deposition. The contribution of the facility to outdoor deposited particle mass was further estimated by three independent models using the measurements obtained from this study. The estimated contributions to particle deposition in the study area were 1.8-7.4% from the regression analysis of the Ca concentration in particle deposition samples against the distance from the facility, 0-11% from the U.S. Environmental Protection Agency (EPA) Chemical Mass Balance (CMB) source-receptor model, and 7.6-13% from the EPA Industrial Source Complex Short Term (ISCST3) dispersion model using the particle-size-adjusted permit-based emissions estimates. [Box: see text].

  14. Continuous downstream processing for high value biological products: A Review.

    PubMed

    Zydney, Andrew L

    2016-03-01

    There is growing interest in the possibility of developing truly continuous processes for the large-scale production of high value biological products. Continuous processing has the potential to provide significant reductions in cost and facility size while improving product quality and facilitating the design of flexible multi-product manufacturing facilities. This paper reviews the current state-of-the-art in separations technology suitable for continuous downstream bioprocessing, focusing on unit operations that would be most appropriate for the production of secreted proteins like monoclonal antibodies. This includes cell separation/recycle from the perfusion bioreactor, initial product recovery (capture), product purification (polishing), and formulation. Of particular importance are the available options, and alternatives, for continuous chromatographic separations. Although there are still significant challenges in developing integrated continuous bioprocesses, recent technological advances have provided process developers with a number of attractive options for development of truly continuous bioprocessing operations. © 2015 Wiley Periodicals, Inc.

  15. Good Manufacturing Practices (GMP) manufacturing of advanced therapy medicinal products: a novel tailored model for optimizing performance and estimating costs.

    PubMed

    Abou-El-Enein, Mohamed; Römhild, Andy; Kaiser, Daniel; Beier, Carola; Bauer, Gerhard; Volk, Hans-Dieter; Reinke, Petra

    2013-03-01

    Advanced therapy medicinal products (ATMP) have gained considerable attention in academia due to their therapeutic potential. Good Manufacturing Practice (GMP) principles ensure the quality and sterility of manufacturing these products. We developed a model for estimating the manufacturing costs of cell therapy products and optimizing the performance of academic GMP-facilities. The "Clean-Room Technology Assessment Technique" (CTAT) was tested prospectively in the GMP facility of BCRT, Berlin, Germany, then retrospectively in the GMP facility of the University of California-Davis, California, USA. CTAT is a two-level model: level one identifies operational (core) processes and measures their fixed costs; level two identifies production (supporting) processes and measures their variable costs. The model comprises several tools to measure and optimize performance of these processes. Manufacturing costs were itemized using adjusted micro-costing system. CTAT identified GMP activities with strong correlation to the manufacturing process of cell-based products. Building best practice standards allowed for performance improvement and elimination of human errors. The model also demonstrated the unidirectional dependencies that may exist among the core GMP activities. When compared to traditional business models, the CTAT assessment resulted in a more accurate allocation of annual expenses. The estimated expenses were used to set a fee structure for both GMP facilities. A mathematical equation was also developed to provide the final product cost. CTAT can be a useful tool in estimating accurate costs for the ATMPs manufactured in an optimized GMP process. These estimates are useful when analyzing the cost-effectiveness of these novel interventions. Copyright © 2013 International Society for Cellular Therapy. Published by Elsevier Inc. All rights reserved.

  16. Development of a Medical Cyclotron Production Facility

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Allen, Danny R.

    Development of a Cyclotron manufacturing facility begins with a business plan. Geographics, the size and activity of the medical community, the growth potential of the modality being served, and other business connections are all considered. This business used the customer base established by NuTech, Inc., an independent centralized nuclear pharmacy founded by Danny Allen. With two pharmacies in operation in Tyler and College Station and a customer base of 47 hospitals and clinics the existing delivery system and pharmacist staff is used for the cyclotron facility. We then added cyclotron products to contracts with these customers to guarantee a supply.more » We partnered with a company in the process of developing PET imaging centers. We then built an independent imaging center attached to the cyclotron facility to allow for the use of short-lived isotopes.« less

  17. Medical Isotope Production Analyses In KIPT Neutron Source Facility

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Talamo, Alberto; Gohar, Yousry

    Medical isotope production analyses in Kharkov Institute of Physics and Technology (KIPT) neutron source facility were performed to include the details of the irradiation cassette and the self-shielding effect. An updated detailed model of the facility was used for the analyses. The facility consists of an accelerator-driven system (ADS), which has a subcritical assembly using low-enriched uranium fuel elements with a beryllium-graphite reflector. The beryllium assemblies of the reflector have the same outer geometry as the fuel elements, which permits loading the subcritical assembly with different number of fuel elements without impacting the reflector performance. The subcritical assembly is drivenmore » by an external neutron source generated from the interaction of 100-kW electron beam with a tungsten target. The facility construction was completed at the end of 2015, and it is planned to start the operation during the year of 2016. It is the first ADS in the world, which has a coolant system for removing the generated fission power. Argonne National Laboratory has developed the design concept and performed extensive design analyses for the facility including its utilization for the production of different radioactive medical isotopes. 99Mo is the parent isotope of 99mTc, which is the most commonly used medical radioactive isotope. Detailed analyses were performed to define the optimal sample irradiation location and the generated activity, for several radioactive medical isotopes, as a function of the irradiation time.« less

  18. [Airborne particles in a multi-wall carbon nanotube production plant: observation of particle emission and personal exposure 1: Measurement in the packing process].

    PubMed

    Takaya, Mitsutoshi; Serita, Fumio; Ono-Ogasawara, Mariko; Shinohara, Yasushi; Saito, Hiroyuki; Koda, Shigeki

    2010-01-01

    In order to assess the exposure risks of multiwall carbon nanotubes (MWCNT) for packing workers, we carried out real-time monitoring in the two types of packing facilities of MWCNT, and exposure measurements for the packing workers. In the real-time monitoring, a scanning mobility particle sizer (SMPS) and an optical particle counter (OPC) were used to measure nanoscale particles and sub-micron/micron scale particles, respectively. A personal sampler with PM 4.0 was used to measure the personal exposures in the packing facilities. One of the packing facilities is manually operated and the other is automated. The concentrations of airborne dust in both facilities were almost the same as each other at 0.24 mg/m(3) (total dust). However, the results of personal exposure measurements were quite different between the two facilities. The exposure concentrations of workers in the manually and automated operations were 2.39/0.39 (total/respirable) mg/m(3) and 0.29/0.08 (total/respirable) mg/m(3), respectively. From the time series study, submicron scale particles were released into the workplace air when the CNT products were put into temporary container bags from a hopper and manually packed into shipping bags. However, the task-related nanoscale particle release was not observed. The manual packing operation is one of the "hot spots" in MWCNT production facilities, and automation brings much improvement to reduce MWCNT exposure.

  19. Consumer Response to Gastrointestinal Illness Perceived To Originate from Food Service Facilities.

    PubMed

    Garnett, Erin S; Gretsch, Stephanie R; Null, Clair; Moe, Christine L

    2016-10-01

    Consumer responses to food product recalls have been documented, but there is little information on how consumers respond to illnesses or outbreaks associated with food service facilities. This study uses an on-line survey of 885 adults conducted in 2012 to determine how respondents changed their dining behavior following personal experiences with and secondhand reports of gastrointestinal illness believed to be associated with food service facilities. In response to personally experiencing gastrointestinal illness that they attributed to a food service facility, 90% of survey participants reported that they avoided the implicated facility for a time following the incident; almost one-half decided to never return to the facility they believed had made them ill. In response to a secondhand report of gastrointestinal illness, 86% of respondents reported they would avoid the implicated facility for a time, and 22% said they would never return to the facility. After both personal experiences of illness and secondhand reports of illness, consumer responses were significantly more severe toward the implicated facility than toward all other food service facilities. Frequent diners avoided facilities for shorter periods of time and were less likely to never go back to a facility than were infrequent diners. The survey results indicate that 24 to 97 fewer meals were purchased per respondent, or a 11 to 20% reduction in meals purchased outside the home, in the year following respondents' illness. Future estimates of the economic burden of foodborne illnesses, including those caused by noroviruses, should consider the impacts on the food service industry attributable to changes in consumer behavior, in addition to health care costs and loss of productivity.

  20. Third-Party Evaluation: A Review of Dietary Supplements Dispensed by Military Treatment Facilities From 2007 to 2011.

    PubMed

    Jones, Donnamaria R; Kasper, Korey B; Deuster, Patricia A

    2015-07-01

    Third-party certification/verification of dietary supplements (DS), although not mainstream, is one way to help ensure high-quality products. In the medical setting, physicians may prescribe DS to correct a deficiency or improve a health care outcome, and they want products of a certain standard of quality, free of adulteration/contamination. We reviewed DS dispensed from all Department of Defense military treatment facilities over a 5-year period to determine which products had been third-party reviewed and certified/verified. By using product name, manufacturer, and/or National Drug Codes, we examined product listings on the websites of three independent-evaluating organizations. Over 1.5 million dietary supplement prescriptions consisting of 753 different products were dispensed from 2007 through 2011. Less than 3.6% of the products examined were third-party certified/verified by any of the three most well-known evaluation organizations: 19 were verified by United States Pharmacopeial Convention; 9 products were reviewed and 8 certified by ConsumerLab; and none of the products were certified by NSF International. Most DS dispensed by military treatment facilities are not reviewed by a third party. This is not unexpected, as third party certification is not yet mainstream. However, one way to reduce potential hazards and exposure to unsafe products is to encourage use of supplements that have third-party certification/verification. Reprint & Copyright © 2015 Association of Military Surgeons of the U.S.

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