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Sample records for products registration applications

  1. 75 FR 5077 - Pesticide Product; Registration Application

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-01

    ... AGENCY Pesticide Product; Registration Application AGENCY: Environmental Protection Agency (EPA). ACTION: Notice. SUMMARY: EPA has received an application to register a pesticide product containing an active ingredient not included in any previously registered pesticide products. Pursuant to the provisions...

  2. 75 FR 80490 - Pesticide Products; Registration Applications

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-22

    ... AGENCY Pesticide Products; Registration Applications AGENCY: Environmental Protection Agency (EPA). ACTION: Notice. SUMMARY: EPA has received applications to register pesticide products containing active ingredients not included in any previously registered pesticide products. Pursuant to the provisions...

  3. 75 FR 24694 - Pesticide Products; Registration Applications

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-05

    ... AGENCY Pesticide Products; Registration Applications AGENCY: Environmental Protection Agency (EPA). ACTION: Notice. SUMMARY: EPA has received applications to register pesticide products containing an active ingredient not included in any previously registered pesticide product. Pursuant to the provisions...

  4. 76 FR 38160 - Pesticide Products; Registration Applications

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-29

    ... AGENCY Pesticide Products; Registration Applications AGENCY: Environmental Protection Agency (EPA). ACTION: Notice. SUMMARY: EPA has received applications to register pesticide products containing an active ingredient not included in any previously registered pesticide products. Pursuant to the...

  5. 77 FR 14362 - Pesticide Products; Registration Applications

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-09

    ... AGENCY Pesticide Products; Registration Applications AGENCY: Environmental Protection Agency (EPA). ACTION: Notice. SUMMARY: This notice announces receipt of applications to register pesticide products... by the docket identification (ID) number and the file symbol for the pesticide of interest as...

  6. 77 FR 38285 - Pesticide Products; Registration Applications

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-27

    ... AGENCY Pesticide Products; Registration Applications AGENCY: Environmental Protection Agency (EPA). ACTION: Notice. SUMMARY: This notice announces receipt of applications to register pesticide products...), Office of Pesticide Programs, Environmental Protection Agency, 1200 Pennsylvania Ave. NW., Washington,...

  7. 75 FR 71695 - Pesticide Products; Registration Applications

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-24

    ... AGENCY Pesticide Products; Registration Applications AGENCY: Environmental Protection Agency ACTION: Notice. SUMMARY: EPA has received applications to register new uses for pesticide products containing... Pesticide Programs (OPP) Regulatory Public Docket (7502P), Environmental Protection Agency, 1200...

  8. 75 FR 11884 - Pesticide Products; Registration Applications

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-12

    ... AGENCY Pesticide Products; Registration Applications AGENCY: Environmental Protection Agency (EPA). ACTION: Notice. SUMMARY: This notice announces receipt of applications to register new uses for pesticide...: Office of Pesticide Programs (OPP) Regulatory Public Docket (7502P), Environmental Protection...

  9. 75 FR 32767 - Pesticide Products; Registration Applications

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-09

    ... AGENCY Pesticide Products; Registration Applications AGENCY: Environmental Protection Agency (EPA). ACTION: Notice. SUMMARY: This notice announces receipt of applications to register new uses for pesticide...: Office of Pesticide Programs (OPP) Regulatory Public Docket (7502P), Environmental Protection Agency...

  10. 75 FR 53692 - Pesticide Products; Registration Applications

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-01

    ...] Pesticide Products; Registration Applications AGENCY: Environmental Protection Agency (EPA). ACTION: Notice. SUMMARY: This notice announces receipt of applications to register new uses for pesticide products... notice of such applications, pursuant to section 3(c)(4) of FIFRA. DATES: Comments must be received on or...

  11. 75 FR 19388 - Pesticide Product; Registration Application

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-14

    ... AGENCY Pesticide Product; Registration Application AGENCY: Environmental Protection Agency (EPA). ACTION: Notice. SUMMARY: EPA has received an application to register a pesticide product containing an active... providing notice of receipt and opportunity to comment on this application. ] DATES: Comments must be...

  12. 75 FR 56105 - Pesticide Products; Registration Applications

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-15

    ... affected entities may include, but are not limited to: Crop production (NAICS code 111). Animal production... Company, 10805 W. Timberwagon Circle, Spring, TX 77380. Active ingredient: 1-Naphthaleneadcetic acid...

  13. 75 FR 11175 - Pesticide Products; Registration Applications

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-10

    ... Apply to Me? You may be potentially affected by this action if you are an agricultural producer, food...: Crop production (NAICS code 111). Animal production (NAICS code 112). Food manufacturing (NAICS code... 190, Marysville, OH 43040). Product Name: Phoma Tech. Active Ingredient: Phoma macrostoma strain...

  14. 75 FR 13282 - Pesticide Products; Registration Applications

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-19

    ...: Glyphosate. Proposed Use: Roundup ready sweet corn. Contact: Erik Kraft, (703) 308-9358, kraft.erik@epa.gov... affected entities may include, but are not limited to: Crop production (NAICS code 111). Animal production.... Company name and address: Syngenta Crop Protection, Inc., P.O. Box 18300, Greensboro, NC 27419....

  15. 75 FR 4384 - Pesticide Products; Registration Applications

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-27

    ...: Indaziflam 500 SC Herbicide. Active ingredient: Herbicide with Indaziflam at 45.05%. Proposed use: Pre... Park, NC 27709. Product name: Indaziflam 200 SC Herbicide. Active ingredient: Herbicide with Indaziflam.... Box 30, Newark, DE 19714. Product name: DPX-MAT28 Technical Herbicide. Active ingredient:...

  16. 75 FR 71697 - Pesticide Products; Registration Applications

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-24

    ...: 87485-E. Docket number: EPA-HQ-OPP-2010-0685. Applicant: Michael T. Novak; Keller and Heckman, LLP; 1001.... Novak; Keller and Heckman, LLP; 1001 G Street, NW.; Washington, DC 20001(on behalf of DSM Food...

  17. 76 FR 17645 - Pesticide Products; Registration Applications

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-30

    ... active ingredient aldicarb. Pursuant to the provisions of section 3(c)(4) of the Federal Insecticide..., Chapel Hill, NC 27514. Product name: Memik 15G. Active ingredient: Insecticide aldicarb at 15.0...

  18. 76 FR 17644 - Pesticide Product; Registration Application

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-30

    ... section 3(c)(4) of the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), EPA is hereby..., Vancouver, WA 98685. Product name: Isomate-DWB. Active ingredient: Insecticides; (E,Z)-2,13- Octadecadien- 1...

  19. 75 FR 8939 - Pesticide Products; Registration Applications

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-26

    ... provisions of section 3(c)(4) of the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), EPA is... products containing the active ingredient spirotetramat - a tetramic acid derivative insecticide - under section 3 of the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), 7 U.S.C. 136a, for use on a...

  20. 77 FR 12295 - Pesticide Products; Registration Applications

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-29

    .... Active ingredient: Plant-Incorporated Protectant with Bacillus thuringiensis Cry1F protein and the genetic material (PHP27118 T-DNA) necessary for its production in Event DP- 4114-3 corn and Bacillus...: Phyllom grubGONE! Granular (G). Active ingredient: Insecticide with Bacillus thuringiensis...

  1. 76 FR 5805 - Pesticide Products; Registration Applications

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-02

    .... Active ingredient: Plant growth regulator, Salicylic Acid, at 0.04%. Proposed classification/Use.... Active ingredient: Plant growth regulator, Salicylic Acid, at 0.0067%. Proposed classification/Use... Consulting, Inc., 4110 136th St., NW., Gig Harbor, WA 98332. Product name: Salicylic Acid Technical....

  2. 77 FR 72342 - Notice of Receipt of Pesticide Products; Registration Applications

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-05

    ... AGENCY Notice of Receipt of Pesticide Products; Registration Applications AGENCY: Environmental Protection Agency (EPA). ACTION: Notice. SUMMARY: EPA has received applications to register pesticide products containing an active ingredient not included in any currently registered pesticide...

  3. 78 FR 76612 - Notice of Receipt of Pesticide Products; Registration Applications To Register New Uses

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-18

    ... into end-use sulfentrazone products used for weed control in apple orchards. 3. EPA Registration... use: Weed control in apple orchards. 4. EPA Registration Number: 7969-155. Docket ID number: EPA-HQ...

  4. 40 CFR 152.42 - Application for new registration.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 24 2014-07-01 2014-07-01 false Application for new registration. 152... PROGRAMS PESTICIDE REGISTRATION AND CLASSIFICATION PROCEDURES Registration Procedures § 152.42 Application for new registration. Any person seeking to obtain a registration for a new pesticide product...

  5. 78 FR 48677 - Notice of Receipt of Pesticide Products; Registration Applications to Register New Uses

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-09

    .... Docket ID number: EPA-HQ-OPP-2013-0034. Applicant: E.I. du Pont de Nemours and Company, 1007 Market...: Postemergence application to sorghum containing the ALS-tolerant ``DuPont INZEN Z'' trait. 4. EPA Registration Numbers: 352-555, 352-748, and 352-816. Docket ID number: EPA-HQ-OPP-2013-0035. Applicant: E.I. du Pont de...

  6. 40 CFR 152.42 - Application for new registration.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Application for new registration. 152... for new registration. Any person seeking to obtain a registration for a new pesticide product must... for new registration must be approved by the Agency before the product may legally be distributed or...

  7. 40 CFR 152.42 - Application for new registration.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 25 2013-07-01 2013-07-01 false Application for new registration. 152... for new registration. Any person seeking to obtain a registration for a new pesticide product must... for new registration must be approved by the Agency before the product may legally be distributed or...

  8. 40 CFR 152.42 - Application for new registration.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 25 2012-07-01 2012-07-01 false Application for new registration. 152... for new registration. Any person seeking to obtain a registration for a new pesticide product must... for new registration must be approved by the Agency before the product may legally be distributed or...

  9. Main Reasons for Registration Application Refusal of Generic and Similar Pharmaceutical Drug Products by the Brazilian Health Regulatory Agency (ANVISA).

    PubMed

    do Carmo, Ana Cerúlia Moraes; Piras, Stefânia Schimaneski; Rocha, Nayrton Flávio Moura; Gratieri, Tais

    2017-01-01

    Objective. The marketing authorization of generic and similar pharmaceutical drug products involves the analysis of proposing company's administrative aspects as well as drug product technical description and scientific evaluations. This study evaluated the main reasons for registration refusal of generic and similar pharmaceutical drug products in Brazil. The aim is to help future applicants to better organize the proposal. Methods. A retrospective search of drug products registration processes was performed on the Brazilian Government Official Gazette from January 1, 2015, and December 31, 2015. Results. Drug product quality control, drug product stability study, deadline accomplishment, API quality control made by drug manufacturer, active pharmaceutical ingredient (API), and production report were the main reasons for marketing authorization application refusal of generic and similar pharmaceutical drug products in 2015. Conclusion. Disclosure of the reasons behind failed applications is a step forward on regulatory transparency. Sharing of experiences is essential to international regulatory authorities and organizations to improve legislation requirements for the marketing authorization of generic and similar pharmaceutical drug products.

  10. Main Reasons for Registration Application Refusal of Generic and Similar Pharmaceutical Drug Products by the Brazilian Health Regulatory Agency (ANVISA)

    PubMed Central

    do Carmo, Ana Cerúlia Moraes; Piras, Stefânia Schimaneski; Rocha, Nayrton Flávio Moura

    2017-01-01

    Objective. The marketing authorization of generic and similar pharmaceutical drug products involves the analysis of proposing company's administrative aspects as well as drug product technical description and scientific evaluations. This study evaluated the main reasons for registration refusal of generic and similar pharmaceutical drug products in Brazil. The aim is to help future applicants to better organize the proposal. Methods. A retrospective search of drug products registration processes was performed on the Brazilian Government Official Gazette from January 1, 2015, and December 31, 2015. Results. Drug product quality control, drug product stability study, deadline accomplishment, API quality control made by drug manufacturer, active pharmaceutical ingredient (API), and production report were the main reasons for marketing authorization application refusal of generic and similar pharmaceutical drug products in 2015. Conclusion. Disclosure of the reasons behind failed applications is a step forward on regulatory transparency. Sharing of experiences is essential to international regulatory authorities and organizations to improve legislation requirements for the marketing authorization of generic and similar pharmaceutical drug products. PMID:28280742

  11. 40 CFR 152.44 - Application for amended registration.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    .... 152.44 Section 152.44 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS PESTICIDE REGISTRATION AND CLASSIFICATION PROCEDURES Registration Procedures § 152.44 Application... designated residential use products). A consolidated application must clearly identify the labeling...

  12. 40 CFR 152.44 - Application for amended registration.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    .... 152.44 Section 152.44 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS PESTICIDE REGISTRATION AND CLASSIFICATION PROCEDURES Registration Procedures § 152.44 Application... designated residential use products). A consolidated application must clearly identify the labeling...

  13. 40 CFR 152.44 - Application for amended registration.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    .... 152.44 Section 152.44 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS PESTICIDE REGISTRATION AND CLASSIFICATION PROCEDURES Registration Procedures § 152.44 Application... designated residential use products). A consolidated application must clearly identify the labeling...

  14. 78 FR 76613 - Registration Applications for Pesticide Products Containing New Active Ingredients; Corrections

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-18

    ... in the Federal Register of August 14, 2012, concerning a new active ingredient (AI). The name of an AI was changed during the registration assessment process. This document corrects the name of the...

  15. 78 FR 78356 - Notice of Receipt of Pesticide Products; Registration Applications To Register New Uses

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-26

    .... Potentially affected entities may include: Crop production (NAICS code 111). Animal production (NAICS code 112... ingredient: Pseudomonas fluorescens strain CL145A cells and spent fermentation media. Product type...

  16. 77 FR 75152 - Notice of Receipt of Pesticide Products; Registration Applications

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-19

    ... Agrochemicals, Ltd., Active ingredient: Prohydrojasmon (PDJ) at 98%. Product type: Plant Growth Regulator....25%. Product type: Plant Growth Regulator. Proposed use: Fruit color development/color enhancement on...

  17. 14 CFR 380.62 - Registration applications.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 4 2013-01-01 2013-01-01 false Registration applications. 380.62 Section... PROCEEDINGS) SPECIAL REGULATIONS PUBLIC CHARTERS Registration of Foreign Charter Operators § 380.62 Registration applications. (a) To be registered under this subpart, a foreign charter operator shall file...

  18. 14 CFR 380.62 - Registration applications.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 4 2012-01-01 2012-01-01 false Registration applications. 380.62 Section... PROCEEDINGS) SPECIAL REGULATIONS PUBLIC CHARTERS Registration of Foreign Charter Operators § 380.62 Registration applications. (a) To be registered under this subpart, a foreign charter operator shall file...

  19. 14 CFR 380.62 - Registration applications.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Registration applications. 380.62 Section... PROCEEDINGS) SPECIAL REGULATIONS PUBLIC CHARTERS Registration of Foreign Charter Operators § 380.62 Registration applications. (a) To be registered under this subpart, a foreign charter operator shall file...

  20. 14 CFR 380.62 - Registration applications.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 4 2014-01-01 2014-01-01 false Registration applications. 380.62 Section... PROCEEDINGS) SPECIAL REGULATIONS PUBLIC CHARTERS Registration of Foreign Charter Operators § 380.62 Registration applications. (a) To be registered under this subpart, a foreign charter operator shall file...

  1. 14 CFR 380.62 - Registration applications.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 4 2011-01-01 2011-01-01 false Registration applications. 380.62 Section... PROCEEDINGS) SPECIAL REGULATIONS PUBLIC CHARTERS Registration of Foreign Charter Operators § 380.62 Registration applications. (a) To be registered under this subpart, a foreign charter operator shall file...

  2. 77 FR 59611 - Notice of Receipt of Pesticide Products; Registration Applications

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-28

    ... Symbol: 85004-RN. Docket ID Number: EPA-HQ-OPP-2012- 0609. Applicant: Pasteuria Bioscience, Inc., 12085... Symbol: 85004-RR. Docket ID Number: EPA-HQ-OPP-2012- 0609. Applicant: Pasteuria Bioscience, Inc.,...

  3. 77 FR 75153 - Notice of Receipt of Pesticide Products; Registration Applications To Register New Uses

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-19

    ...: Insecticide. Proposed Uses: All food and feed commodities to support applications to control adult mosquitoes.... Proposed Uses: All food and feed commodities to support applications to control adult mosquitoes. Contact...

  4. 78 FR 53139 - Pesticide Product Registration; Receipt of Application for New Uses

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-28

    ... new food uses on previously registered pesticide products containing the insecticide flonicamid, pursuant to the provisions of the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA). DATES... registered pesticide products containing the insecticide, flonicamid (N-(cyanomethyl)-4-(trifluoromethyl)-3...

  5. 75 FR 6386 - Pesticide Products; Registration Applications for a New Active Ingredient Chemical; Demiditraz

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-09

    ... pesticide products. Pursuant to the provisions of section 3(c)(4) of the Federal Insecticide, Fungicide, and.... Product name: Demiditraz Technical. Active ingredient: Insecticide and Demiditraz at 100%. Proposed...., Kalamazoo, MI 49001. Product name: CA Acaricide. Active ingredient: Insecticide and Demiditraz at 17.5...

  6. 78 FR 64937 - Pesticide Products; Registration Applications for New Active Ingredients

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-30

    .... Pursuant to the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), EPA is hereby providing notice..., Japan. Active ingredient: Momfluorothrin. Product type: Insecticide. Proposed uses: Non-food residential...

  7. 78 FR 32246 - Pesticide Products; Registration Applications for New Active Ingredients

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-29

    ..., hay, crop group 18; coffee, bean, green; coffee, bean, roasted, instant; hops; peanut, hay; peanut... ID Number: EPA-HQ-OPP-2013- 0226. Applicant: Bayer CropScience LP, 2 T.W. Alexander Drive, P.O. Box...- 0257. Applicant: Technology Sciences Group, Inc., on behalf of Alpha Scents, Inc., 1150 18th Street,...

  8. 78 FR 70043 - Pesticide Product Registration; Receipt of an Application for a New Active Ingredient

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-22

    ... providing notice of receipt and opportunity to comment on the application. DATES: Comments must be received... personal threats. viii. Make sure to submit your comments by the comment period deadline identified. II... section 3(c)(4), EPA is hereby providing notice of receipt and opportunity to comment on the application...

  9. 78 FR 55695 - Notice of Receipt of Pesticide Products; Registration Applications To Register New Uses

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-11

    ...-IIE and 352-ITI. Docket ID Number: EPA-HQ-OPP-2013-0528. Applicant: DuPont Crop Protection, Stine...-728 and 352-730. Docket ID Number: EPA-HQ-OPP-2013-0235. Applicant: DuPont Crop Protection, Stine...

  10. 77 FR 77077 - Pesticide Product Registration; Receipt of Applications for New Uses

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-31

    ... pesticide products containing currently registered active ingredients. Pursuant to the Federal Insecticide... Triangle Park, NC 27709. Active Ingredient: Spirotetramat. Product Type: Insecticide. Proposed Uses...: Insecticide. Proposed Use: To control darkling beetles in poultry house litter. Contact: Linda DeLuise, (703...

  11. 78 FR 75343 - Pesticide Products; Registration Applications for New Active Ingredients

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-11

    .... Pursuant to the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), EPA is hereby providing notice...: Chromobacterium subtsugae strain SB3872. Product type: Microbial insecticide. Proposed uses: Commercial ground and...: Beauveria bassiana strain ANT-03. Product type: Microbial insecticide. Proposed uses: Foliar-applied...

  12. 78 FR 21945 - Notice of Receipt of Pesticide Products; Registration Applications To Register New Uses

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-12

    ... provisions of section 3(c) of the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), as amended...: Insecticide. Proposed Use: Technical Flonicamid Insecticide for Manufacturing and Repacking Use Only Products..., Concord, OH 44077. Active ingredient: Flonicamid. Product Type: Insecticide. Proposed Uses: Almond; Almond...

  13. 78 FR 32245 - Notice of Receipt of Pesticide Products; Registration Applications To Register New Uses

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-29

    .... Product Type: Herbicide. Proposed Use: Lima Beans. Contact: Michael Walsh, (703) 308- 2972, email address... Regulator. Proposed Uses: Control of fleas, roaches, flies, mosquitoes, gnats, litter beetles, and ants...

  14. 77 FR 66836 - Notice of Receipt of Pesticide Products; Registration Applications

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-07

    ... (Mating Disruptor) with Carob Moth Pheromone Mimic (7,9,11-Dodecatrien-1-ol, formate at 90.8%. Product... 92507. Active ingredient: Biochemical Pheromone (Mating Disruptor) with Carob Moth Pheromone Mimic...

  15. 77 FR 48519 - Registration Applications for Pesticide Products Containing New Active Ingredients

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-14

    ... telephone, email, or mail. Mail correspondence to the Biopesticides and Pollution Prevention Division (7511P... entities likely to be affected by this action. Other types of entities not listed in this unit could also.... israelensis, Strain SUM-6218 at 100.0%. Product Type: microbial insecticide. Proposed Use: Manufacturing use...

  16. 78 FR 23558 - Pesticide Products; Registration Applications for New Active Ingredients

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-19

    .... Pursuant to the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), EPA is hereby providing notice... ingredient: Streptomyces microflavus strain AQ 6121. Product Type: e.g., Insecticide/Miticide. Proposed Uses... Type: Insecticide. Proposed Use: Agriculture (outdoors). Contact: Michael Glikes, (BPPD), (703) 305...

  17. 78 FR 9389 - Notice of Receipt of Pesticide Products; Registration Applications To Register New Uses

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-08

    ... provisions of section 3(c) of the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), as amended...: Insecticide. Proposed Use: Barley, fruiting vegetable group 8-10, citrus fruit group 10-10, pome fruit group... ingredient: Methoxyfenozide. Product Type: Insecticide. Proposed Use: Herb subgroup 19A (except chives...

  18. 78 FR 59347 - Pesticides; Revised Fee Schedule for Registration Applications

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-26

    ... products for use against bacteria, protozoa, non-agricultural fungi, and viruses. AD is also responsible... From the Federal Register Online via the Government Publishing Office ENVIRONMENTAL PROTECTION AGENCY Pesticides; Revised Fee Schedule for Registration Applications AGENCY: Environmental...

  19. 21 CFR 710.6 - Notification of registrant; cosmetic product establishment registration number.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 7 2014-04-01 2014-04-01 false Notification of registrant; cosmetic product... OF HEALTH AND HUMAN SERVICES (CONTINUED) COSMETICS VOLUNTARY REGISTRATION OF COSMETIC PRODUCT ESTABLISHMENTS § 710.6 Notification of registrant; cosmetic product establishment registration number. The...

  20. 21 CFR 710.6 - Notification of registrant; cosmetic product establishment registration number.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 7 2012-04-01 2012-04-01 false Notification of registrant; cosmetic product... OF HEALTH AND HUMAN SERVICES (CONTINUED) COSMETICS VOLUNTARY REGISTRATION OF COSMETIC PRODUCT ESTABLISHMENTS § 710.6 Notification of registrant; cosmetic product establishment registration number. The...

  1. 21 CFR 710.6 - Notification of registrant; cosmetic product establishment registration number.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 7 2013-04-01 2013-04-01 false Notification of registrant; cosmetic product... OF HEALTH AND HUMAN SERVICES (CONTINUED) COSMETICS VOLUNTARY REGISTRATION OF COSMETIC PRODUCT ESTABLISHMENTS § 710.6 Notification of registrant; cosmetic product establishment registration number. The...

  2. 21 CFR 710.6 - Notification of registrant; cosmetic product establishment registration number.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 7 2010-04-01 2010-04-01 false Notification of registrant; cosmetic product... OF HEALTH AND HUMAN SERVICES (CONTINUED) COSMETICS VOLUNTARY REGISTRATION OF COSMETIC PRODUCT ESTABLISHMENTS § 710.6 Notification of registrant; cosmetic product establishment registration number. The...

  3. Pesticide Registration Manual: Biopesticide Application Checklists Documents

    EPA Pesticide Factsheets

    These checklists are used by reviewers in the Biopesticide and Pollution Prevention Division in their review of pesticide registration applications. Applicants can use them to help ensure their packages are complete.

  4. 21 CFR 710.6 - Notification of registrant; cosmetic product establishment registration number.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... permanent registration number will be assigned to each cosmetic product establishment registered in... establishment registration number. 710.6 Section 710.6 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT... ESTABLISHMENTS § 710.6 Notification of registrant; cosmetic product establishment registration number. The...

  5. 46 CFR 401.200 - Application for registration.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false Application for registration. 401.200 Section 401.200 Shipping COAST GUARD (GREAT LAKES PILOTAGE), DEPARTMENT OF HOMELAND SECURITY GREAT LAKES PILOTAGE REGULATIONS Registration of Pilots § 401.200 Application for registration. (a) An application for registration...

  6. 46 CFR 401.200 - Application for registration.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 8 2012-10-01 2012-10-01 false Application for registration. 401.200 Section 401.200 Shipping COAST GUARD (GREAT LAKES PILOTAGE), DEPARTMENT OF HOMELAND SECURITY GREAT LAKES PILOTAGE REGULATIONS Registration of Pilots § 401.200 Application for registration. (a) An application for registration...

  7. 78 FR 24195 - Product Cancellation Order for Certain Pesticide Registrations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-24

    ... Cancel Certain Pesticide Registrations, in order to pursue alternative formulation and product design... AGENCY Product Cancellation Order for Certain Pesticide Registrations AGENCY: Environmental Protection..., voluntarily requested by the registrants and accepted by the Agency, of the products listed in Table 1. and...

  8. 40 CFR 152.44 - Application for amended registration.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 24 2014-07-01 2014-07-01 false Application for amended registration... PROGRAMS PESTICIDE REGISTRATION AND CLASSIFICATION PROCEDURES Registration Procedures § 152.44 Application for amended registration. (a) Except as provided by § 152.46, any modification in the...

  9. 40 CFR 152.44 - Application for amended registration.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 25 2013-07-01 2013-07-01 false Application for amended registration... PROGRAMS PESTICIDE REGISTRATION AND CLASSIFICATION PROCEDURES Registration Procedures § 152.44 Application for amended registration. (a) Except as provided by § 152.46, any modification in the...

  10. 21 CFR 1309.25 - Temporary exemption from registration for chemical registration applicants.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... distribute, import, or export a combination ephedrine product is temporarily exempted from the registration... or import prescription drug products containing ephedrine, pseudoephedrine, or phenylpropanolamine...

  11. 21 CFR 1309.25 - Temporary exemption from registration for chemical registration applicants.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... distribute, import, or export a combination ephedrine product is temporarily exempted from the registration... or import prescription drug products containing ephedrine, pseudoephedrine, or phenylpropanolamine...

  12. 21 CFR 1309.25 - Temporary exemption from registration for chemical registration applicants.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... distribute, import, or export a combination ephedrine product is temporarily exempted from the registration... or import prescription drug products containing ephedrine, pseudoephedrine, or phenylpropanolamine...

  13. Landsat image registration for agricultural applications

    NASA Technical Reports Server (NTRS)

    Wolfe, R. H., Jr.; Juday, R. D.; Wacker, A. G.; Kaneko, T.

    1982-01-01

    An image registration system has been developed at the NASA Johnson Space Center (JSC) to spatially align multi-temporal Landsat acquisitions for use in agriculture and forestry research. Working in conjunction with the Master Data Processor (MDP) at the Goddard Space Flight Center, it functionally replaces the long-standing LACIE Registration Processor as JSC's data supplier. The system represents an expansion of the techniques developed for the MDP and LACIE Registration Processor, and it utilizes the experience gained in an IBM/JSC effort evaluating the performance of the latter. These techniques are discussed in detail. Several tests were developed to evaluate the registration performance of the system. The results indicate that 1/15-pixel accuracy (about 4m for Landsat MSS) is achievable in ideal circumstances, sub-pixel accuracy (often to 0.2 pixel or better) was attained on a representative set of U.S. acquisitions, and a success rate commensurate with the LACIE Registration Processor was realized. The system has been employed in a production mode on U.S. and foreign data, and a performance similar to the earlier tests has been noted.

  14. 40 CFR 152.42 - Application for new registration.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 24 2011-07-01 2011-07-01 false Application for new registration. 152.42 Section 152.42 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS PESTICIDE REGISTRATION AND CLASSIFICATION PROCEDURES Registration Procedures § 152.42 Application...

  15. 77 FR 26004 - Product Cancellation Order for Certain Pesticide Registrations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-02

    ... Imazapyr Imazapyr. Technical 98%. 086068-00001 Texcan Glyphosate Glyphosate. Technical. 086068-00002 Texcan 62% Glyphosate- Glyphosate MUP. isopropylammonium. Table 2--Registrations for Products...

  16. 27 CFR 447.32 - Application for registration and refund of fee.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 3 2011-04-01 2010-04-01 true Application for registration and refund of fee. 447.32 Section 447.32 Alcohol, Tobacco Products, and Firearms BUREAU OF ALCOHOL... the registrant ceases to engage in importing articles on the U.S. Munitions Import List. A request for...

  17. 21 CFR 1301.13 - Application for registration; time for application; expiration date; registration for independent...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... the form of a personal, certified, or cashier's check or money order made payable to the “Drug... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Application for registration; time for application...; coincident activities. 1301.13 Section 1301.13 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT...

  18. 21 CFR 1301.13 - Application for registration; time for application; expiration date; registration for independent...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... the form of a personal, certified, or cashier's check or money order made payable to the “Drug... 21 Food and Drugs 9 2014-04-01 2014-04-01 false Application for registration; time for application...; coincident activities. 1301.13 Section 1301.13 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT...

  19. 21 CFR 1301.13 - Application for registration; time for application; expiration date; registration for independent...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... the form of a personal, certified, or cashier's check or money order made payable to the “Drug... 21 Food and Drugs 9 2013-04-01 2013-04-01 false Application for registration; time for application...; coincident activities. 1301.13 Section 1301.13 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT...

  20. 21 CFR 1301.13 - Application for registration; time for application; expiration date; registration for independent...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... the form of a personal, certified, or cashier's check or money order made payable to the “Drug... 21 Food and Drugs 9 2012-04-01 2012-04-01 false Application for registration; time for application...; coincident activities. 1301.13 Section 1301.13 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT...

  1. 21 CFR 1309.25 - Temporary exemption from registration for chemical registration applicants.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 9 2012-04-01 2012-04-01 false Temporary exemption from registration for chemical registration applicants. 1309.25 Section 1309.25 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT OF.... The exemption will remain in effect for each person who has made such application until...

  2. 21 CFR 1309.25 - Temporary exemption from registration for chemical registration applicants.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Temporary exemption from registration for chemical registration applicants. 1309.25 Section 1309.25 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT OF.... The exemption will remain in effect for each person who has made such application until...

  3. 21 CFR 607.35 - Notification of registrant; blood product establishment registration number and NDC Labeler Code.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 7 2012-04-01 2012-04-01 false Notification of registrant; blood product... PRODUCT LISTING FOR MANUFACTURERS OF HUMAN BLOOD AND BLOOD PRODUCTS Procedures for Domestic Blood Product Establishments § 607.35 Notification of registrant; blood product establishment registration number and...

  4. 21 CFR 607.35 - Notification of registrant; blood product establishment registration number and NDC Labeler Code.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 7 2013-04-01 2013-04-01 false Notification of registrant; blood product... PRODUCT LISTING FOR MANUFACTURERS OF HUMAN BLOOD AND BLOOD PRODUCTS Procedures for Domestic Blood Product Establishments § 607.35 Notification of registrant; blood product establishment registration number and...

  5. 21 CFR 607.35 - Notification of registrant; blood product establishment registration number and NDC Labeler Code.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 7 2014-04-01 2014-04-01 false Notification of registrant; blood product... PRODUCT LISTING FOR MANUFACTURERS OF HUMAN BLOOD AND BLOOD PRODUCTS Procedures for Domestic Blood Product Establishments § 607.35 Notification of registrant; blood product establishment registration number and...

  6. 21 CFR 607.35 - Notification of registrant; blood product establishment registration number and NDC Labeler Code.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 7 2010-04-01 2010-04-01 false Notification of registrant; blood product... PRODUCT LISTING FOR MANUFACTURERS OF HUMAN BLOOD AND BLOOD PRODUCTS Procedures for Domestic Blood Product Establishments § 607.35 Notification of registrant; blood product establishment registration number and...

  7. Meetings with Registrants of Pet Spot-on Products

    EPA Pesticide Factsheets

    Information about EPA efforts to mitigate adverse effects from spot-on products used on pets and the meetings the agency had with producers, or registrants of the products to discuss product-specific mitigation.

  8. Image registration for luminescent paint applications

    NASA Technical Reports Server (NTRS)

    Bell, James H.; Mclachlan, Blair G.

    1993-01-01

    The use of pressure sensitive luminescent paints is a viable technique for the measurement of surface pressure on wind tunnel models. This technique requires data reduction of images obtained under known as well as test conditions and spatial transformation of the images. A general transform which registers images to subpixel accuracy is presented and the general characteristics of transforms for image registration and their derivation are discussed. Image resection and its applications are described. The mapping of pressure data to the three dimensional model surface for small wind tunnel models to a spatial accuracy of 0.5 percent of the model length is demonstrated.

  9. 10 CFR 32.210 - Registration of product information.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 1 2010-01-01 2010-01-01 false Registration of product information. 32.210 Section 32.210 Energy NUCLEAR REGULATORY COMMISSION SPECIFIC DOMESTIC LICENSES TO MANUFACTURE OR TRANSFER CERTAIN ITEMS CONTAINING BYPRODUCT MATERIAL Specifically Licensed Items § 32.210 Registration of product information. (a...

  10. 21 CFR 1301.13 - Application for registration; time for application; expiration date; registration for independent...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... registered, shall make application for registration for one of the following groups of controlled substances... the form of a personal, certified, or cashier's check or money order made payable to the “Drug..., Hospital/Clinic, Retail Pharmacy, Online Pharmacy, Central fill pharmacy, Teaching Institution) Schedules...

  11. 40 CFR 154.21 - Preliminary notification to registrants and applicants for registration.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 24 2011-07-01 2011-07-01 false Preliminary notification to registrants and applicants for registration. 154.21 Section 154.21 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS SPECIAL REVIEW PROCEDURES Procedures § 154.21...

  12. 40 CFR 154.21 - Preliminary notification to registrants and applicants for registration.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Preliminary notification to registrants and applicants for registration. 154.21 Section 154.21 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS SPECIAL REVIEW PROCEDURES Procedures § 154.21...

  13. 78 FR 55061 - Proposed Information Collection; Comment Request; Applications and Reports for Registration as a...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-09

    ...; Applications and Reports for Registration as a Tanner or Agent AGENCY: National Oceanic and Atmospheric... or agent for such native products must register with NOAA and maintain and submit certain records...

  14. 77 FR 21971 - Proposed Information Collection; Comment Request; Applications and Reports for Registration as a...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-12

    ...; Applications and Reports for Registration as a Tanner or Agent AGENCY: National Oceanic and Atmospheric... no permit, but non-natives who wish to act as a tanner or agent for such native products must...

  15. 76 FR 40359 - Product Cancellation Order for Certain Pesticide Registrations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-08

    ...--Cancellations of Registrations Containing Methyl Bromide EPA registration number Product name Chemical name 003377-00009 Methyl Bromide Methyl bromide. Technical. 005785-00023 Terr-O-Gas 45....... Chloropicrin. Methyl bromide. 008622-00040 57-43 Preplant Soil Methyl bromide. Fumigant. Chloropicrin. 008622-00044 80...

  16. 17 CFR 240.6a-1 - Application for registration as a national securities exchange or exemption from registration...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... as a national securities exchange or exemption from registration based on limited volume. 240.6a-1... national securities exchange or exemption from registration based on limited volume. (a) An application for registration as a national securities exchange, or for exemption from such registration based on limited...

  17. 17 CFR 240.6a-1 - Application for registration as a national securities exchange or exemption from registration...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... as a national securities exchange or exemption from registration based on limited volume. 240.6a-1... national securities exchange or exemption from registration based on limited volume. (a) An application for registration as a national securities exchange, or for exemption from such registration based on limited...

  18. 17 CFR 240.6a-1 - Application for registration as a national securities exchange or exemption from registration...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... as a national securities exchange or exemption from registration based on limited volume. 240.6a-1... national securities exchange or exemption from registration based on limited volume. (a) An application for registration as a national securities exchange, or for exemption from such registration based on limited...

  19. 17 CFR 240.6a-1 - Application for registration as a national securities exchange or exemption from registration...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... as a national securities exchange or exemption from registration based on limited volume. 240.6a-1... national securities exchange or exemption from registration based on limited volume. (a) An application for registration as a national securities exchange, or for exemption from such registration based on limited...

  20. 17 CFR 240.6a-1 - Application for registration as a national securities exchange or exemption from registration...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... as a national securities exchange or exemption from registration based on limited volume. 240.6a-1... national securities exchange or exemption from registration based on limited volume. (a) An application for registration as a national securities exchange, or for exemption from such registration based on limited...

  1. 22 CFR 50.3 - Application for registration.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Application for registration. 50.3 Section 50.3 Foreign Relations DEPARTMENT OF STATE NATIONALITY AND PASSPORTS NATIONALITY PROCEDURES Procedures for Determination of United States Nationality of a Person Abroad § 50.3 Application for registration. (a) A person...

  2. 22 CFR 50.3 - Application for registration.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Application for registration. 50.3 Section 50.3 Foreign Relations DEPARTMENT OF STATE NATIONALITY AND PASSPORTS NATIONALITY PROCEDURES Procedures for Determination of United States Nationality of a Person Abroad § 50.3 Application for registration. (a) A person...

  3. 22 CFR 50.3 - Application for registration.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Application for registration. 50.3 Section 50.3 Foreign Relations DEPARTMENT OF STATE NATIONALITY AND PASSPORTS NATIONALITY PROCEDURES Procedures for Determination of United States Nationality of a Person Abroad § 50.3 Application for registration. (a) A person...

  4. 22 CFR 50.3 - Application for registration.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Application for registration. 50.3 Section 50.3 Foreign Relations DEPARTMENT OF STATE NATIONALITY AND PASSPORTS NATIONALITY PROCEDURES Procedures for Determination of United States Nationality of a Person Abroad § 50.3 Application for registration. (a) A person...

  5. 77 FR 74278 - Proposed Information Collection (Internet Student CPR Web Registration Application); Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-13

    ... AFFAIRS Proposed Information Collection (Internet Student CPR Web Registration Application); Comment... solicits comments on information needed to establish an online web registration application. DATES: Written... use of other forms of information technology. Title: Internet Student CPR Web Registration Application...

  6. 75 FR 28012 - Pesticides; Draft Guidance for Pesticide Registrants on False or Misleading Pesticide Product...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-19

    ... Brand Names AGENCY: Environmental Protection Agency (EPA). ACTION: Notice of availability. SUMMARY: The... Notice (PR Notice) entitled ``False or Misleading Pesticide Product Brand Names.'' PR Notices are issued... applicants, registrants and distributors concerning pesticide product brand names that may be false or...

  7. 22 CFR 50.3 - Application for registration.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... area a matter of record. (b) The applicant shall execute the registration form prescribed by the Department and shall submit the supporting evidence required by subpart C of part 51 of this chapter....

  8. PR notice 86-4. Notice to registrants of pesticides, and applicants for pesticide registration

    SciTech Connect

    Not Available

    1986-04-01

    The document is one in the series of Pesticide Regulatory Notices, usually called PR Notices, which supplement the laws and regulations governing pesticide regulation in the US. These notices clarify, interpret and explain regulatory requirements and policies. They are directed at pesticide registrants and other parties interested in detailed procedures of regulation. This notice announces a new Environmental Protection Agency (EPA) policy regarding incomplete applications for registration of pesticides under section 3 of the Federal Insecticide, Fungicide and Rodenticide Act (FIFRA), 7 USC 136a et seq. This notice also specifies new requirements for submitting applications to the Agency in order to implement this policy.

  9. Registration in neurosurgery and neuroradiotherapy applications.

    PubMed

    Cuchet, E; Knoplioch, J; Dormont, D; Marsault, C

    1995-01-01

    Because of the high level of accuracy needed in neurosurgery, many computer-assisted surgery (CAS) and augmented reality techniques have been developed in this field. A common issue with all of these techniques is registration between preoperative three-dimensional images (computed tomography and magnetic resonance imaging) and the patient in the operating room. We present, in the first part of this paper, a survey of the latest CAS technologies, using fully automatic registration without fiducial landmarks. All of the registration algorithms described are based on minimization of a cost function. We then describe our approach. Our cost function is simply the mean square error (MSE), minimized by the iterative closest point algorithm (ICP). Because the weak point of the ICP algorithm is the closest point computational cost, we precalculate it by a "closest point map," inspired from classical distance map. We finally perturb the found solution to eliminate local minima close to the global minimum. This paper summarizes the various methods presented. We study the shape of the different cost functions and show that there is no need for a complex cost function. MSE has sufficiently good convergence properties to reach a position very close to the global minimum. We also demonstrate the influence of a final perturbation of the found solution to improve registration. Finally, we test the registration on different regions of the patient's head.

  10. 21 CFR 607.40 - Establishment registration and blood product listing requirements for foreign blood product...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 7 2012-04-01 2012-04-01 false Establishment registration and blood product listing requirements for foreign blood product establishments. 607.40 Section 607.40 Food and Drugs FOOD... REGISTRATION AND PRODUCT LISTING FOR MANUFACTURERS OF HUMAN BLOOD AND BLOOD PRODUCTS Procedures for...

  11. 21 CFR 607.40 - Establishment registration and blood product listing requirements for foreign blood product...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 7 2013-04-01 2013-04-01 false Establishment registration and blood product listing requirements for foreign blood product establishments. 607.40 Section 607.40 Food and Drugs FOOD... REGISTRATION AND PRODUCT LISTING FOR MANUFACTURERS OF HUMAN BLOOD AND BLOOD PRODUCTS Procedures for...

  12. 21 CFR 607.40 - Establishment registration and blood product listing requirements for foreign blood product...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 7 2014-04-01 2014-04-01 false Establishment registration and blood product listing requirements for foreign blood product establishments. 607.40 Section 607.40 Food and Drugs FOOD... REGISTRATION AND PRODUCT LISTING FOR MANUFACTURERS OF HUMAN BLOOD AND BLOOD PRODUCTS Procedures for...

  13. 21 CFR 607.40 - Establishment registration and blood product listing requirements for foreign blood product...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 7 2010-04-01 2010-04-01 false Establishment registration and blood product listing requirements for foreign blood product establishments. 607.40 Section 607.40 Food and Drugs FOOD... REGISTRATION AND PRODUCT LISTING FOR MANUFACTURERS OF HUMAN BLOOD AND BLOOD PRODUCTS Procedures for...

  14. 75 FR 82387 - Product Cancellation Order for Certain Pesticide Registrations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-30

    ... 1B of Unit II., pursuant to section 6(f)(1) of the Federal Insecticide, Fungicide, and Rodenticide... fenoxycarb product registrations and the notice dated August 18, 2010, pertains to the propetamphos product... received no comments in response to the August 18, 2010 or August 25, 2010 Federal Register...

  15. 75 FR 20842 - Pirimicarb; Product Cancellation Order for Certain Pesticide Registrations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-21

    ... expiration of conditional registrations. Any distribution, sale, or use of the products subject to this... AGENCY Pirimicarb; Product Cancellation Order for Certain Pesticide Registrations AGENCY: Environmental... products containing the pesticide pirimicarb, pursuant to section 3 of the Federal Insecticide,...

  16. 77 FR 6560 - Pesticide Product Registration Approval

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-08

    ... product, Contram ST-1, as an antimicrobial preservative to inhibit the growth of bacteria and fungi in... Number (52484-3) as a preservative to inhibit the growth of bacteria and fungi in metalworking, cutting...

  17. 75 FR 11174 - Pesticide Product Registration Approval

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-10

    ... application from the U.S. Department of Agriculture, Animal and Plant Health Inspection Service (USDA, APHIS... Mammalian Gonadotropin Releasing Hormone (GnRH), and information on social, economic, and environmental... the U.S. Department of Agriculture, Animal and Plant Health Inspection Service (USDA,...

  18. Registration of veterinary products in Argentina.

    PubMed

    Butler, E; Cané, B G

    1995-12-01

    A scheme for registering pharmaceutical and biological products for veterinary use was introduced in Argentina in 1994, as part of a joint scheme for countries of the Common Market of the South (Mercado Común del Sur: "Mercosur'). The authors describe the main features of these regulations, and the process which led to their development.

  19. 76 FR 35411 - Applications for Trademark Registration

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-17

    ... Trademark Electronic Application System (TEAS) using a regular TEAS application form or a TEAS Plus application form. Applicants that file their applications using the TEAS Plus form pay a reduced filing fee if... through TEAS, and agree to receive communications concerning the application by e-mail. TEAS...

  20. Medical image registration algorithms assesment: Bronze Standard application enactment on grids using the MOTEUR workflow engine.

    PubMed

    Glatard, Tristan; Montagnat, Johan; Pennec, Xavier

    2006-01-01

    Medical image registration is pre-processing needed for many medical image analysis procedures. A very large number of registration algorithms are available today, but their performance is often not known and very difficult to assess due to the lack of gold standard. The Bronze Standard algorithm is a very data and compute intensive statistical approach for quantifying registration algorithms accuracy. In this paper, we describe the Bronze Standard application and we discuss the need for grids to tackle such computations on medical image databases. We demonstrate MOTEUR, a service-based workflow engine optimized for dealing with data intensive applications. MOTEUR eases the enactment of the Bronze Standard and similar applications on the EGEE production grid infrastructure. It is a generic workflow engine, based on current standards and freely available, that can be used to instrument legacy application code at low cost.

  1. 75 FR 61750 - Chloroneb; Product Cancellation Order for Certain Pesticide Registrations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-06

    ... AGENCY Chloroneb; Product Cancellation Order for Certain Pesticide Registrations AGENCY: Environmental... containing the pesticide chloroneb, pursuant to section 3 of the Federal Insecticide, Fungicide, and... certain chloroneb time-limited registrations. These are not the last products containing this pesticide...

  2. 40 CFR 152.114 - Approval of registration under FIFRA sec. 3(c)(7)-Products that contain a new active ingredient.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... sec. 3(c)(7)-Products that contain a new active ingredient. 152.114 Section 152.114 Protection of... CLASSIFICATION PROCEDURES Agency Review of Applications § 152.114 Approval of registration under FIFRA sec. 3(c)(7)—Products that contain a new active ingredient. An application for registration of a...

  3. 40 CFR 152.114 - Approval of registration under FIFRA sec. 3(c)(7)-Products that contain a new active ingredient.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... sec. 3(c)(7)-Products that contain a new active ingredient. 152.114 Section 152.114 Protection of... CLASSIFICATION PROCEDURES Agency Review of Applications § 152.114 Approval of registration under FIFRA sec. 3(c)(7)—Products that contain a new active ingredient. An application for registration of a...

  4. 40 CFR 152.114 - Approval of registration under FIFRA sec. 3(c)(7)-Products that contain a new active ingredient.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... sec. 3(c)(7)-Products that contain a new active ingredient. 152.114 Section 152.114 Protection of... CLASSIFICATION PROCEDURES Agency Review of Applications § 152.114 Approval of registration under FIFRA sec. 3(c)(7)—Products that contain a new active ingredient. An application for registration of a...

  5. 40 CFR 152.114 - Approval of registration under FIFRA sec. 3(c)(7)-Products that contain a new active ingredient.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... sec. 3(c)(7)-Products that contain a new active ingredient. 152.114 Section 152.114 Protection of... CLASSIFICATION PROCEDURES Agency Review of Applications § 152.114 Approval of registration under FIFRA sec. 3(c)(7)—Products that contain a new active ingredient. An application for registration of a...

  6. Scope and applications of translation invariant wavelets to image registration

    NASA Technical Reports Server (NTRS)

    Chettri, Samir; LeMoigne, Jacqueline; Campbell, William

    1997-01-01

    The first part of this article introduces the notion of translation invariance in wavelets and discusses several wavelets that have this property. The second part discusses the possible applications of such wavelets to image registration. In the case of registration of affinely transformed images, we would conclude that the notion of translation invariance is not really necessary. What is needed is affine invariance and one way to do this is via the method of moment invariants. Wavelets or, in general, pyramid processing can then be combined with the method of moment invariants to reduce the computational load.

  7. 75 FR 54147 - Product Cancellation Order for Certain Pesticide Registrations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-03

    .... The cancellation was voluntarily requested by the registrant, Ticks and Mosquitoes, LLC., and accepted..., containing the chemicals calcium lactate and urea, was requested by the registrant, Ticks or...

  8. Review Process for the Registration and Use Directions for Floor Wipe Towelette Products

    EPA Pesticide Factsheets

    This guidance provides Antimicrobials Division staff with guidance related to the registration requirements and use directions for presaturated/impregnated floor wipe towelette products. This document will be used for new and existing wipe registrations.

  9. 28 CFR 72.3 - Applicability of the Sex Offender Registration and Notification Act.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 28 Judicial Administration 2 2014-07-01 2014-07-01 false Applicability of the Sex Offender...) SEX OFFENDER REGISTRATION AND NOTIFICATION § 72.3 Applicability of the Sex Offender Registration and Notification Act. The requirements of the Sex Offender Registration and Notification Act apply to all...

  10. 28 CFR 72.3 - Applicability of the Sex Offender Registration and Notification Act.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 28 Judicial Administration 2 2011-07-01 2011-07-01 false Applicability of the Sex Offender...) SEX OFFENDER REGISTRATION AND NOTIFICATION § 72.3 Applicability of the Sex Offender Registration and Notification Act. The requirements of the Sex Offender Registration and Notification Act apply to all...

  11. 28 CFR 72.3 - Applicability of the Sex Offender Registration and Notification Act.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 28 Judicial Administration 2 2013-07-01 2013-07-01 false Applicability of the Sex Offender...) SEX OFFENDER REGISTRATION AND NOTIFICATION § 72.3 Applicability of the Sex Offender Registration and Notification Act. The requirements of the Sex Offender Registration and Notification Act apply to all...

  12. 28 CFR 72.3 - Applicability of the Sex Offender Registration and Notification Act.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Applicability of the Sex Offender...) SEX OFFENDER REGISTRATION AND NOTIFICATION § 72.3 Applicability of the Sex Offender Registration and Notification Act. The requirements of the Sex Offender Registration and Notification Act apply to all...

  13. 28 CFR 72.3 - Applicability of the Sex Offender Registration and Notification Act.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 28 Judicial Administration 2 2012-07-01 2012-07-01 false Applicability of the Sex Offender...) SEX OFFENDER REGISTRATION AND NOTIFICATION § 72.3 Applicability of the Sex Offender Registration and Notification Act. The requirements of the Sex Offender Registration and Notification Act apply to all...

  14. 21 CFR 607.25 - Information required for establishment registration and blood product listing.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... registration and blood product listing. 607.25 Section 607.25 Food and Drugs FOOD AND DRUG ADMINISTRATION... FOR MANUFACTURERS OF HUMAN BLOOD AND BLOOD PRODUCTS Procedures for Domestic Blood Product Establishments § 607.25 Information required for establishment registration and blood product listing. (a)...

  15. 21 CFR 607.25 - Information required for establishment registration and blood product listing.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... registration and blood product listing. 607.25 Section 607.25 Food and Drugs FOOD AND DRUG ADMINISTRATION... FOR MANUFACTURERS OF HUMAN BLOOD AND BLOOD PRODUCTS Procedures for Domestic Blood Product Establishments § 607.25 Information required for establishment registration and blood product listing. (a)...

  16. 21 CFR 607.25 - Information required for establishment registration and blood product listing.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... registration and blood product listing. 607.25 Section 607.25 Food and Drugs FOOD AND DRUG ADMINISTRATION... FOR MANUFACTURERS OF HUMAN BLOOD AND BLOOD PRODUCTS Procedures for Domestic Blood Product Establishments § 607.25 Information required for establishment registration and blood product listing. (a)...

  17. 21 CFR 607.25 - Information required for establishment registration and blood product listing.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... registration and blood product listing. 607.25 Section 607.25 Food and Drugs FOOD AND DRUG ADMINISTRATION... FOR MANUFACTURERS OF HUMAN BLOOD AND BLOOD PRODUCTS Procedures for Domestic Blood Product Establishments § 607.25 Information required for establishment registration and blood product listing. (a)...

  18. 21 CFR 607.21 - Times for establishment registration and blood product listing.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 7 2014-04-01 2014-04-01 false Times for establishment registration and blood... MANUFACTURERS OF HUMAN BLOOD AND BLOOD PRODUCTS Procedures for Domestic Blood Product Establishments § 607.21 Times for establishment registration and blood product listing. The owner or operator of...

  19. 21 CFR 607.21 - Times for establishment registration and blood product listing.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 7 2011-04-01 2010-04-01 true Times for establishment registration and blood... MANUFACTURERS OF HUMAN BLOOD AND BLOOD PRODUCTS Procedures for Domestic Blood Product Establishments § 607.21 Times for establishment registration and blood product listing. The owner or operator of...

  20. 21 CFR 607.21 - Times for establishment registration and blood product listing.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 7 2012-04-01 2012-04-01 false Times for establishment registration and blood... MANUFACTURERS OF HUMAN BLOOD AND BLOOD PRODUCTS Procedures for Domestic Blood Product Establishments § 607.21 Times for establishment registration and blood product listing. The owner or operator of...

  1. 21 CFR 607.21 - Times for establishment registration and blood product listing.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 7 2013-04-01 2013-04-01 false Times for establishment registration and blood... MANUFACTURERS OF HUMAN BLOOD AND BLOOD PRODUCTS Procedures for Domestic Blood Product Establishments § 607.21 Times for establishment registration and blood product listing. The owner or operator of...

  2. 21 CFR 607.21 - Times for establishment registration and blood product listing.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 7 2010-04-01 2010-04-01 false Times for establishment registration and blood... MANUFACTURERS OF HUMAN BLOOD AND BLOOD PRODUCTS Procedures for Domestic Blood Product Establishments § 607.21 Times for establishment registration and blood product listing. The owner or operator of...

  3. 21 CFR 607.37 - Inspection of establishment registrations and blood product listings.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 7 2011-04-01 2010-04-01 true Inspection of establishment registrations and blood... MANUFACTURERS OF HUMAN BLOOD AND BLOOD PRODUCTS Procedures for Domestic Blood Product Establishments § 607.37 Inspection of establishment registrations and blood product listings. (a) A copy of the Form FD-2830...

  4. 77 FR 74003 - Pesticides; Draft Guidance for Pesticide Registrants on Antimicrobial Pesticide Products With...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-12

    ... AGENCY Pesticides; Draft Guidance for Pesticide Registrants on Antimicrobial Pesticide Products With Mold... Registration Notice (PR Notice) titled ``Guidance on Antimicrobial Pesticide Products with Mold-Related Label... (efficacy) data and labeling for ``mold-related'' pesticide products. EPA believes that the label...

  5. 40 CFR 152.114 - Approval of registration under FIFRA sec. 3(c)(7)-Products that contain a new active ingredient.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS PESTICIDE REGISTRATION AND...)(7)—Products that contain a new active ingredient. An application for registration of a pesticide... § 152.112(a), (b), (d), and (f) through (h) have been satisfied; (d) The use of the pesticide...

  6. 78 FR 72879 - Product Cancellation Order for Certain Pesticide Registrations; Correction

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-04

    ... column (EPA Company No.), remove the entry: 1021. List of Subjects Environmental protection, Pesticides... AGENCY Product Cancellation Order for Certain Pesticide Registrations; Correction AGENCY: Environmental... September 20, 2013, concerning the product cancellation of several pesticide products, which were...

  7. 76 FR 51031 - Registration; Cancellation Order for Rodenticide Products That Have Expired

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-17

    ... 1--Registrations and Product Names EPA Registration No. Product name 47629-14 Difenacoum Rat and Mouse Pellets (consumer use only). 47629-16 Difenacoum Rat and Mouse Block (consumer use only). 47629-17 Difenacoum Rat and Mouse Place Packs (consumer use only). 47629-11 Bromethalin Rat & Mouse Block....

  8. 75 FR 66095 - Pesticide Products; Registration Applications

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-27

    ... edible beans, dry peas, soybean, oilseeds canola/ rapeseed subgroup 20A, oilseeds sunflower subgroup 20B... canola/rapeseed subgroup 20A, oilseeds sunflower subgroup 20B, and oilseeds cottonseed subgroup...

  9. 76 FR 10026 - Pesticide Products; Registration Applications

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-23

    ... St., NW., Washington, DC 20001. Active ingredient: Hydrogen Peroxide at 23% and Ethaneperoxoic Acid... ingredient: Hydrogen Peroxide. Proposed Use: Materials preservative applied to textiles for commercial...

  10. 76 FR 4688 - Pesticide Products; Registration Applications

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-26

    ... 27419. Active ingredient: Paraquat dichloride. Proposed Use(s): Atemoya, biriba, black sapote, canistel... beet molasses, bulb onion subgroup, peanut nutmeat, peanut hay and dried tea leaves. Contact: Kable Bo...

  11. 76 FR 63298 - Pesticide Products; Registration Applications

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-12

    ... thuringiensis subsp. kurstaki strain VBTS 2546 fermentation solids, spores, and insecticidal toxins at 67... ingredient: Bacillus thuringiensis subsp. kurstaki strain VBTS 2546 fermentation solids, spores, and...

  12. 75 FR 20841 - Pesticide Products; Registration Applications

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-21

    ... seed; cucurbit vegetables (crop group 9; excluding cantaloupe, pumpkin, watermelon, winter squash); cantaloupe; pumpkin; watermelon; winter squash; edible-podded legume vegetables (subgroup 6A); field...

  13. 75 FR 51045 - Pesticide Products; Registration Applications

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-18

    ..., cereals except rice, corn, legume vegetables (dry), sorghum, and soybeans. Contact: Susan Stanton, (703... soil-borne plant diseases on canola, cereal grains except rice, corn, legume vegetables (dry),...

  14. 75 FR 23759 - Pesticide Products; Registration Applications

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-04

    ...: Ametoctradin at 19.2%. Proposed classification/Use: Terrestrial food use for brassica leafy vegetables, bulb... Ametoctradin at 26.9%. Proposed classification/Use: Terrestrial food use for brassica leafy vegetables, bulb...

  15. 75 FR 24695 - Pesticide Products; Registration Applications

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-05

    ....gov , your e-mail address will be automatically captured and included as part of the comment that is... part or all of the information that you claim to be CBI. For CBI information in a disk or CD-ROM that... so marked will not be disclosed except in accordance with procedures set forth in 40 CFR part 2. 2...

  16. 75 FR 34114 - Pesticide Products; Registration Applications

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-16

    ... & 16); vegetables, legume, including soybeans (CG 6 & 7); canola, borage, crambe, cuphea, echium, flax..., cereal grains (CG 15 & 16); corn, rice, canola, borage, crambe, cuphea, echium, flax seed, gold of... & 16); corn, rice, canola, borage, crambe, cuphea, echium, flax seed, gold of pleasure, hare's ear...

  17. 75 FR 3235 - Pesticide Products; Registration Applications

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-20

    ... provisions of section 3(c)(4) of the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), as amended... formulating agricultural pesticide formulations, plant growth, regulators, herbicides, fungicides, seed...

  18. 75 FR 26754 - Pesticide Products; Registration Applications

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-12

    ... vegetable group, leafy vegetable group, peas/beans (dry), pome fruit group, potato, stone fruit group... group, fruiting vegetable group, leafy vegetable group, peas/beans (dry), pome fruit group, potato... group, leafy vegetable group, peas/beans (dry), pome fruit group, potato, stone fruit group,...

  19. 76 FR 16413 - Pesticide Products; Registration Applications

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-23

    ... treatment on alfalfa, potato, and rice; seed treatment on alfalfa, barley, dry bean and peas (crop subgroup 6C), potato, rice, soybeans, triticale, and wheat; and nursery seed and seedlings of conifers and..., lunaria, meadowfoam, milkweed, mustard seed, oil radish, poppy seed, rapeseed (canola), sesame, and sweet...

  20. 75 FR 4383 - Pesticide Products: Registration Applications

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-27

    ... (703) 305-5805. FOR FURTHER INFORMATION CONTACT: Gina Casciano, Biopesticides and Pollution Prevention..., 2010. Keith A. Matthews, Acting Director, Biopesticides and Pollution Prevention Division, Office...

  1. 75 FR 6656 - Pesticide Product; Registration Application

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-10

    ... your comment and with any disk or CD-ROM you submit. If EPA cannot read your comment due to technical..., is not placed on the Internet and will be publicly available only in hard copy form. Publicly..., if only available in hard copy, at the OPP Regulatory Public Docket in Rm. S-4400, One Potomac Yard...

  2. 76 FR 26291 - Pesticide Products; Registration Applications

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-06

    ..., Rm. S-4400, One Potomac Yard (South Bldg.), 2777 S. Crystal Dr., Arlington, VA. Deliveries are only....), 2777 S. Crystal Dr., Arlington, VA. The hours of operation of this Docket Facility are from 8:30 a.m..., spanish lime, starfruit, sugar apple, wax jambu, rambutan, and persimmon. Contact: Rita Kumar...

  3. 75 FR 10259 - Pesticide Products; Registration Applications

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-05

    ...), Environmental Protection Agency, Rm. S-4400, One Potomac Yard (South Bldg.), 2777 S. Crystal Dr., Arlington, VA... (South Bldg.), 2777 S. Crystal Dr., Arlington, VA. The hours of operation of this Docket Facility are..., shade trees, and sugar maple. Contact: Kathleen Martin, (703) 308-2857, martin.kathleen@epa.gov . 5...

  4. 75 FR 76463 - Pesticide Products; Registration Applications

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-08

    ..., Rm. S-4400, One Potomac Yard (South Bldg.), 2777 S. Crystal Dr., Arlington, VA. Deliveries are only....), 2777 S. Crystal Dr., Arlington, VA. The hours of operation of this Docket Facility are from 8:30 a.m... fruit (group 12), sugar beets, and wheat. Contact: Tamue L. Gibson, (703) 305-9096, gibson.tamue@epa.gov...

  5. 75 FR 31785 - Pesticide Products; Registration Applications

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-04

    ...: Fluxapyroxad at 5.96%. Propose uses: Barley, corn, dried shelled peas and beans, edible podded legumes.... Active ingredient: Fluxapyroxad at 28.78%. Proposed uses: Seed treatment use on barley, corn, cotton... ingredient: Fluxapyroxad at 28.70%. Proposed uses: Seed treatment use on barley, corn, cotton, dried...

  6. 37 CFR 2.194 - Identification of trademark application or registration.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Correspondence in Trademark Cases § 2.194 Identification of trademark application or registration. (a) No correspondence relating to a trademark application should be filed prior to receipt of the application...

  7. 75 FR 4973 - Registration Requirements for Importers and Manufacturers of Prescription Drug Products...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-01

    ...The Drug Enforcement Administration (DEA) is amending its registration regulations to ensure that a registration is obtained for every location where ephedrine, pseudoephedrine, or phenylpropanolamine, or drug products containing one of these chemicals, are imported or manufactured. These amendments will make it possible to establish the system of quotas and assessment of annual needs for the......

  8. 75 FR 8340 - Maneb; Product Cancellation Order of a Certain Pesticide Registration

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-24

    ... stakeholders including environmental, human health, and agricultural advocates; the chemical industry... Request from the registrant, Drexel Chemical Company, to voluntarily cancel their product registration... Name and Address 019713 Drexel Chemical Company 1700 Channel Ave. P.O. Box 13327 Memphis, TN 38113 III...

  9. 75 FR 8942 - Maneb; Product Cancellation Order for Certain Pesticide Registrations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-26

    ... stakeholders including environmental, human health, and agricultural advocates; the chemical industry... the registrant, Drexel Chemical Company, to voluntarily cancel these product registrations. These are... Company Number Company Name and Address 019713 Drexel Chemical Company 1700 Channel Ave. P. O. Box 13327...

  10. 22 CFR 50.5 - Application for registration of birth abroad.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Application for registration of birth abroad... for registration of birth abroad. Upon application by the parent(s) or the child's legal guardian, a... Consular Report of Birth Abroad of a Citizen of the United States of America for a child born in...

  11. 22 CFR 50.5 - Application for registration of birth abroad.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Application for registration of birth abroad... for registration of birth abroad. Upon application by the parent(s) or the child's legal guardian, a... Consular Report of Birth Abroad of a Citizen of the United States of America for a child born in...

  12. 22 CFR 50.5 - Application for registration of birth abroad.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Application for registration of birth abroad... for registration of birth abroad. Upon application by the parent(s) or the child's legal guardian, a... Consular Report of Birth Abroad of a Citizen of the United States of America for a child born in...

  13. 22 CFR 50.5 - Application for registration of birth abroad.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Application for registration of birth abroad... for registration of birth abroad. Upon application by the parent(s) or the child's legal guardian, a... Consular Report of Birth Abroad of a Citizen of the United States of America for a child born in...

  14. 22 CFR 50.5 - Application for registration of birth abroad.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Application for registration of birth abroad... for registration of birth abroad. Upon application by the parent(s) or the child's legal guardian, a... Consular Report of Birth Abroad of a Citizen of the United States of America for a child born in their...

  15. 27 CFR 447.32 - Application for registration and refund of fee.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...) Application for registration must be filed on ATF Form 4587 and must be accompanied by the registration fee at the rate prescribed in this section. The appropriate ATF officer will approve the application and... a refund must be submitted to the appropriate ATF officer at the Bureau of Alcohol, Tobacco and...

  16. 49 CFR 365.505 - Re-registration and fee waiver for certain applicants.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 5 2010-10-01 2010-10-01 false Re-registration and fee waiver for certain applicants. 365.505 Section 365.505 Transportation Other Regulations Relating to Transportation (Continued... Carriers § 365.505 Re-registration and fee waiver for certain applicants. (a) If you filed an...

  17. 17 CFR 249.1 - Form 1, for application for, and amendments to applications for, registration as a national...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ..., and amendments to applications for, registration as a national securities exchange or exemption from... or Exemption of, and Notification of Action Taken by, National Securities Exchanges § 249.1 Form 1, for application for, and amendments to applications for, registration as a national...

  18. 17 CFR 249.1 - Form 1, for application for, and amendments to applications for, registration as a national...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ..., and amendments to applications for, registration as a national securities exchange or exemption from... or Exemption of, and Notification of Action Taken by, National Securities Exchanges § 249.1 Form 1, for application for, and amendments to applications for, registration as a national...

  19. 17 CFR 249.1 - Form 1, for application for, and amendments to applications for, registration as a national...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ..., and amendments to applications for, registration as a national securities exchange or exemption from... or Exemption of, and Notification of Action Taken by, National Securities Exchanges § 249.1 Form 1, for application for, and amendments to applications for, registration as a national...

  20. 17 CFR 249.1 - Form 1, for application for, and amendments to applications for, registration as a national...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ..., and amendments to applications for, registration as a national securities exchange or exemption from... or Exemption of, and Notification of Action Taken by, National Securities Exchanges § 249.1 Form 1, for application for, and amendments to applications for, registration as a national...

  1. 17 CFR 249.1 - Form 1, for application for, and amendments to applications for, registration as a national...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ..., and amendments to applications for, registration as a national securities exchange or exemption from... or Exemption of, and Notification of Action Taken by, National Securities Exchanges § 249.1 Form 1, for application for, and amendments to applications for, registration as a national...

  2. 77 FR 10515 - Pesticide Product Registrations; Conditional Approval

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-22

    ... producer, food manufacturer, or pesticide manufacturer. Potentially affected entities may include, but are... registration will not cause any unreasonable adverse effect on the environment, and that use of the pesticide... taken to ensure that use of the pesticides will not result in unreasonable adverse effects to man and...

  3. 75 FR 52737 - Pesticide Product Registrations; Unconditional and Conditional Approvals

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-27

    ....gov . 9. Coat protein gene of plum pox virus also known as the CPG-PPV, or plum pox resistance gene... the active ingredient, coat protein gene of plum pox virus. At the time of submission of the... Plum (EPA Registration Number 11312-8) for resistance to plum pox virus infection. The Agency approved...

  4. 78 FR 57388 - Product Cancellation Order for Certain Pesticide Registrations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-18

    ... received substantive comments within the 30-day comment period that would merit its further review of these... but it did not merit its further review of the requests. Further, the registrants did not withdraw...) 566-1744, and the telephone number for the OPP Docket is (703) 305- 5805. Please review the...

  5. 21 CFR 607.37 - Inspection of establishment registrations and blood product listings.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... blood product listings. 607.37 Section 607.37 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF... MANUFACTURERS OF HUMAN BLOOD AND BLOOD PRODUCTS Procedures for Domestic Blood Product Establishments § 607.37 Inspection of establishment registrations and blood product listings. (a) A copy of the Form FD-2830...

  6. 21 CFR 607.37 - Inspection of establishment registrations and blood product listings.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... blood product listings. 607.37 Section 607.37 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF... MANUFACTURERS OF HUMAN BLOOD AND BLOOD PRODUCTS Procedures for Domestic Blood Product Establishments § 607.37 Inspection of establishment registrations and blood product listings. (a) A copy of the Form FD-2830...

  7. 21 CFR 607.37 - Inspection of establishment registrations and blood product listings.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... blood product listings. 607.37 Section 607.37 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF... MANUFACTURERS OF HUMAN BLOOD AND BLOOD PRODUCTS Procedures for Domestic Blood Product Establishments § 607.37 Inspection of establishment registrations and blood product listings. (a) A copy of the Form FD-2830...

  8. 21 CFR 607.37 - Inspection of establishment registrations and blood product listings.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... blood product listings. 607.37 Section 607.37 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF... MANUFACTURERS OF HUMAN BLOOD AND BLOOD PRODUCTS Procedures for Domestic Blood Product Establishments § 607.37 Inspection of establishment registrations and blood product listings. (a) A copy of the Form FD-2830...

  9. 76 FR 48053 - Consumer Registration of Durable Infant or Toddler Products

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-08

    ... From the Federal Register Online via the Government Publishing Office CONSUMER PRODUCT SAFETY COMMISSION 16 CFR Part 1130 Consumer Registration of Durable Infant or Toddler Products AGENCY: Consumer...(d) of the Consumer Product Safety Improvement Act of 2008 (``CPSIA'') the Consumer Product...

  10. 22 CFR 42.67 - Execution of application, registration, and fingerprinting.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Registration, when it is completed, or it shall be read to the applicant in the applicant's language, or the..., or a designated officer of the American Institute of Taiwan, who shall then sign the application over... completed, or it shall be read to the applicant in the applicant's language, or the applicant...

  11. 17 CFR 249b.300 - FORM NRSRO, application for registration as a nationally recognized statistical rating...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... registration as a nationally recognized statistical rating organization pursuant to section 15E of the... 1934 § 249b.300 FORM NRSRO, application for registration as a nationally recognized statistical rating... nationally recognized statistical rating organization pursuant to section 15E of the Securities Exchange...

  12. 17 CFR 249b.300 - FORM NRSRO, application for registration as a nationally recognized statistical rating...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... registration as a nationally recognized statistical rating organization pursuant to section 15E of the... 1934 § 249b.300 FORM NRSRO, application for registration as a nationally recognized statistical rating... nationally recognized statistical rating organization pursuant to section 15E of the Securities Exchange...

  13. 17 CFR 249b.300 - FORM NRSRO, application for registration as a nationally recognized statistical rating...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... registration as a nationally recognized statistical rating organization pursuant to section 15E of the... 1934 § 249b.300 FORM NRSRO, application for registration as a nationally recognized statistical rating... nationally recognized statistical rating organization pursuant to section 15E of the Securities Exchange...

  14. 17 CFR 249b.300 - FORM NRSRO, application for registration as a nationally recognized statistical rating...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... registration as a nationally recognized statistical rating organization pursuant to section 15E of the... 1934 § 249b.300 FORM NRSRO, application for registration as a nationally recognized statistical rating... nationally recognized statistical rating organization pursuant to section 15E of the Securities Exchange...

  15. 17 CFR 249b.300 - FORM NRSRO, application for registration as a nationally recognized statistical rating...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... registration as a nationally recognized statistical rating organization pursuant to section 15E of the... 1934 § 249b.300 FORM NRSRO, application for registration as a nationally recognized statistical rating... nationally recognized statistical rating organization pursuant to section 15E of the Securities Exchange...

  16. 37 CFR 201.5 - Corrections and amplifications of copyright registrations; applications for supplementary...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2012-07-01 2012-07-01 false Corrections and amplifications of copyright registrations; applications for supplementary registration. 201.5 Section 201.5 Patents, Trademarks, and Copyrights COPYRIGHT OFFICE, LIBRARY OF CONGRESS COPYRIGHT OFFICE AND...

  17. 37 CFR 201.5 - Corrections and amplifications of copyright registrations; applications for supplementary...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2013-07-01 2013-07-01 false Corrections and amplifications of copyright registrations; applications for supplementary registration. 201.5 Section 201.5 Patents, Trademarks, and Copyrights COPYRIGHT OFFICE, LIBRARY OF CONGRESS COPYRIGHT OFFICE AND...

  18. 37 CFR 201.5 - Corrections and amplifications of copyright registrations; applications for supplementary...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2011-07-01 2011-07-01 false Corrections and amplifications of copyright registrations; applications for supplementary registration. 201.5 Section 201.5 Patents, Trademarks, and Copyrights COPYRIGHT OFFICE, LIBRARY OF CONGRESS COPYRIGHT OFFICE AND...

  19. 14 CFR 297.21 - Objections to registration application.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... (AVIATION PROCEEDINGS) ECONOMIC REGULATIONS FOREIGN AIR FREIGHT FORWARDERS AND FOREIGN COOPERATIVE SHIPPERS ASSOCIATIONS Registration for Foreign Air Freight Forwarders and Foreign Cooperative Shippers Associations... freight forwarder or foreign cooperative shippers association shall file their objections with the Office...

  20. 40 CFR 165.65 - Registrants who distribute or sell pesticide products in refillable containers.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... pesticide products in refillable containers. 165.65 Section 165.65 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS PESTICIDE MANAGEMENT AND DISPOSAL Standards for Repackaging Pesticide Products into Refillable Containers § 165.65 Registrants who distribute or sell pesticide products...

  1. 40 CFR 165.65 - Registrants who distribute or sell pesticide products in refillable containers.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... pesticide products in refillable containers. 165.65 Section 165.65 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS PESTICIDE MANAGEMENT AND DISPOSAL Standards for Repackaging Pesticide Products into Refillable Containers § 165.65 Registrants who distribute or sell pesticide products...

  2. 40 CFR 165.65 - Registrants who distribute or sell pesticide products in refillable containers.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... pesticide products in refillable containers. 165.65 Section 165.65 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS PESTICIDE MANAGEMENT AND DISPOSAL Standards for Repackaging Pesticide Products into Refillable Containers § 165.65 Registrants who distribute or sell pesticide products...

  3. 40 CFR 165.65 - Registrants who distribute or sell pesticide products in refillable containers.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... pesticide products in refillable containers. 165.65 Section 165.65 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS PESTICIDE MANAGEMENT AND DISPOSAL Standards for Repackaging Pesticide Products into Refillable Containers § 165.65 Registrants who distribute or sell pesticide products...

  4. 78 FR 9688 - Pesticides; Draft Guidance for Pesticide Registrants on Antimicrobial Pesticide Products With...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-11

    ... AGENCY Pesticides; Draft Guidance for Pesticide Registrants on Antimicrobial Pesticide Products With Mold... for Antimicrobial Pesticide Products with Mold-Related Label Claims. This document extends the comment... guidance for antimicrobial pesticide products with mold-related claims. In response to comments...

  5. 40 CFR 152.115 - Conditions of registration.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 24 2014-07-01 2014-07-01 false Conditions of registration. 152.115... PESTICIDE REGISTRATION AND CLASSIFICATION PROCEDURES Agency Review of Applications § 152.115 Conditions of registration. (a) Substantially similar products and new uses. Each registration issued under § 152.113...

  6. 40 CFR 162.153 - State registration procedures.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 24 2014-07-01 2014-07-01 false State registration procedures. 162.153... STATE REGISTRATION OF PESTICIDE PRODUCTS Regulations Pertaining to State Registration of Pesticides To Meet Special Local Needs § 162.153 State registration procedures. (a) Application for...

  7. 21 CFR 710.8 - Misbranding by reference to registration or to registration number.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... HUMAN SERVICES (CONTINUED) COSMETICS VOLUNTARY REGISTRATION OF COSMETIC PRODUCT ESTABLISHMENTS § 710.8 Misbranding by reference to registration or to registration number. Registration of a cosmetic product...

  8. 21 CFR 710.8 - Misbranding by reference to registration or to registration number.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... HUMAN SERVICES (CONTINUED) COSMETICS VOLUNTARY REGISTRATION OF COSMETIC PRODUCT ESTABLISHMENTS § 710.8 Misbranding by reference to registration or to registration number. Registration of a cosmetic product...

  9. 21 CFR 710.8 - Misbranding by reference to registration or to registration number.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... HUMAN SERVICES (CONTINUED) COSMETICS VOLUNTARY REGISTRATION OF COSMETIC PRODUCT ESTABLISHMENTS § 710.8 Misbranding by reference to registration or to registration number. Registration of a cosmetic product...

  10. 21 CFR 710.8 - Misbranding by reference to registration or to registration number.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... HUMAN SERVICES (CONTINUED) COSMETICS VOLUNTARY REGISTRATION OF COSMETIC PRODUCT ESTABLISHMENTS § 710.8 Misbranding by reference to registration or to registration number. Registration of a cosmetic product...

  11. 21 CFR 710.8 - Misbranding by reference to registration or to registration number.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... HUMAN SERVICES (CONTINUED) COSMETICS VOLUNTARY REGISTRATION OF COSMETIC PRODUCT ESTABLISHMENTS § 710.8 Misbranding by reference to registration or to registration number. Registration of a cosmetic product...

  12. Validation of elastic registration algorithms based on adaptive irregular grids for medical applications

    NASA Astrophysics Data System (ADS)

    Franz, Astrid; Carlsen, Ingwer C.; Renisch, Steffen; Wischmann, Hans-Aloys

    2006-03-01

    Elastic registration of medical images is an active field of current research. Registration algorithms have to be validated in order to show that they fulfill the requirements of a particular clinical application. Furthermore, validation strategies compare the performance of different registration algorithms and can hence judge which algorithm is best suited for a target application. In the literature, validation strategies for rigid registration algorithms have been analyzed. For a known ground truth they assess the displacement error at a few landmarks, which is not sufficient for elastic transformations described by a huge number of parameters. Hence we consider the displacement error averaged over all pixels in the whole image or in a region-of-interest of clinical relevance. Using artificially, but realistically deformed images of the application domain, we use this quality measure to analyze an elastic registration based on transformations defined on adaptive irregular grids for the following clinical applications: Magnetic Resonance (MR) images of freely moving joints for orthopedic investigations, thoracic Computed Tomography (CT) images for the detection of pulmonary embolisms, and transmission images as used for the attenuation correction and registration of independently acquired Positron Emission Tomography (PET) and CT images. The definition of a region-of-interest allows to restrict the analysis of the registration accuracy to clinically relevant image areas. The behaviour of the displacement error as a function of the number of transformation control points and their placement can be used for identifying the best strategy for the initial placement of the control points.

  13. 76 FR 56223 - Agency Information Collection Activities: Application for Registration of Firearms Acquired by...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-12

    ... of Alcohol, Tobacco, Firearms and Explosives Agency Information Collection Activities: Application for Registration of Firearms Acquired by Certain Governmental Entities ACTION: 60-Day Notice. The Department of Justice (DOJ), Bureau of Alcohol, Tobacco, Firearms and Explosives (ATF), will be submitting...

  14. 76 FR 39900 - Agency Information Collection Activities: Application for Registration of Firearms Acquired by...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-07

    ... of Alcohol, Tobacco, Firearms and Explosives Agency Information Collection Activities: Application for Registration of Firearms Acquired by Certain Governmental Entities ACTION: 60-Day Notice. The Department of Justice (DOJ), Bureau of Alcohol, Tobacco, Firearms and Explosives (ATF), will be submitting...

  15. 21 CFR 607.35 - Notification of registrant; blood product establishment registration number and NDC Labeler Code.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... establishment, and a copy will be sent to the reporting official if at another address. A permanent registration... establishment registration number and NDC Labeler Code. 607.35 Section 607.35 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) BIOLOGICS ESTABLISHMENT REGISTRATION AND...

  16. 21 CFR 607.7 - Establishment registration and product listing of blood banks and other firms manufacturing human...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... blood banks and other firms manufacturing human blood and blood products. 607.7 Section 607.7 Food and... ESTABLISHMENT REGISTRATION AND PRODUCT LISTING FOR MANUFACTURERS OF HUMAN BLOOD AND BLOOD PRODUCTS General Provisions § 607.7 Establishment registration and product listing of blood banks and other...

  17. 21 CFR 607.7 - Establishment registration and product listing of blood banks and other firms manufacturing human...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... blood banks and other firms manufacturing human blood and blood products. 607.7 Section 607.7 Food and... ESTABLISHMENT REGISTRATION AND PRODUCT LISTING FOR MANUFACTURERS OF HUMAN BLOOD AND BLOOD PRODUCTS General Provisions § 607.7 Establishment registration and product listing of blood banks and other...

  18. 21 CFR 607.7 - Establishment registration and product listing of blood banks and other firms manufacturing human...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... blood banks and other firms manufacturing human blood and blood products. 607.7 Section 607.7 Food and... ESTABLISHMENT REGISTRATION AND PRODUCT LISTING FOR MANUFACTURERS OF HUMAN BLOOD AND BLOOD PRODUCTS General Provisions § 607.7 Establishment registration and product listing of blood banks and other...

  19. 21 CFR 607.7 - Establishment registration and product listing of blood banks and other firms manufacturing human...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... blood banks and other firms manufacturing human blood and blood products. 607.7 Section 607.7 Food and... ESTABLISHMENT REGISTRATION AND PRODUCT LISTING FOR MANUFACTURERS OF HUMAN BLOOD AND BLOOD PRODUCTS General Provisions § 607.7 Establishment registration and product listing of blood banks and other...

  20. 21 CFR 607.7 - Establishment registration and product listing of blood banks and other firms manufacturing human...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... blood banks and other firms manufacturing human blood and blood products. 607.7 Section 607.7 Food and... ESTABLISHMENT REGISTRATION AND PRODUCT LISTING FOR MANUFACTURERS OF HUMAN BLOOD AND BLOOD PRODUCTS General Provisions § 607.7 Establishment registration and product listing of blood banks and other...

  1. 21 CFR 607.25 - Information required for establishment registration and blood product listing.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 7 2011-04-01 2010-04-01 true Information required for establishment registration and blood product listing. 607.25 Section 607.25 Food and Drugs FOOD AND DRUG ADMINISTRATION... product substances as well as finished dosage forms, by established name as defined in section 502(e)...

  2. 40 CFR 165.67 - Registrants who distribute or sell pesticide products to refillers for repackaging.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... pesticide products to refillers for repackaging. 165.67 Section 165.67 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS PESTICIDE MANAGEMENT AND DISPOSAL Standards for Repackaging Pesticide Products into Refillable Containers § 165.67 Registrants who distribute or sell...

  3. 40 CFR 165.67 - Registrants who distribute or sell pesticide products to refillers for repackaging.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... pesticide products to refillers for repackaging. 165.67 Section 165.67 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS PESTICIDE MANAGEMENT AND DISPOSAL Standards for Repackaging Pesticide Products into Refillable Containers § 165.67 Registrants who distribute or sell...

  4. 40 CFR 165.67 - Registrants who distribute or sell pesticide products to refillers for repackaging.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... pesticide products to refillers for repackaging. 165.67 Section 165.67 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS PESTICIDE MANAGEMENT AND DISPOSAL Standards for Repackaging Pesticide Products into Refillable Containers § 165.67 Registrants who distribute or sell...

  5. 40 CFR 165.67 - Registrants who distribute or sell pesticide products to refillers for repackaging.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... pesticide products to refillers for repackaging. 165.67 Section 165.67 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS PESTICIDE MANAGEMENT AND DISPOSAL Standards for Repackaging Pesticide Products into Refillable Containers § 165.67 Registrants who distribute or sell...

  6. 40 CFR 165.67 - Registrants who distribute or sell pesticide products to refillers for repackaging.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... pesticide products to refillers for repackaging. 165.67 Section 165.67 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS PESTICIDE MANAGEMENT AND DISPOSAL Standards for Repackaging Pesticide Products into Refillable Containers § 165.67 Registrants who distribute or sell...

  7. Global registration of multiple point sets: feasibility and applications in multi-fragment fracture fixation.

    PubMed

    Moghari, Mehdi Hedjazi; Abolmaesumi, Purang

    2007-01-01

    An algorithm to globally register multiple 3D data sets (point sets) within a general reference frame is proposed. The algorithm uses the Unscented Kalman Filter algorithm to simultaneously compute the registration transformations that map the data sets together, and to calculate the variances of the registration parameters. The data sets are either randomly generated, or collected from a set of fractured bone phantoms using Computed Tomography (CT) images. The algorithm robustly converges for isotropic Gaussian noise that could have perturbed the point coordinates in the data sets. It is also computationally efficient, and enables real-time global registration of multiple data sets, with applications in computer-assisted orthopaedic trauma surgery.

  8. Applications of digital image processing techniques to problems of data registration and correlation

    NASA Technical Reports Server (NTRS)

    Green, W. B.

    1978-01-01

    An overview is presented of the evolution of the computer configuration at JPL's Image Processing Laboratory (IPL). The development of techniques for the geometric transformation of digital imagery is discussed and consideration is given to automated and semiautomated image registration, and the registration of imaging and nonimaging data. The increasing complexity of image processing tasks at IPL is illustrated with examples of various applications from the planetary program and earth resources activities. It is noted that the registration of existing geocoded data bases with Landsat imagery will continue to be important if the Landsat data is to be of genuine use to the user community.

  9. Co-registration of Laser Altimeter Tracks with Digital Terrain Models and Applications in Planetary Science

    NASA Technical Reports Server (NTRS)

    Glaeser, P.; Haase, I.; Oberst, J.; Neumann, G. A.

    2013-01-01

    We have derived algorithms and techniques to precisely co-register laser altimeter profiles with gridded Digital Terrain Models (DTMs), typically derived from stereo images. The algorithm consists of an initial grid search followed by a least-squares matching and yields the translation parameters at sub-pixel level needed to align the DTM and the laser profiles in 3D space. This software tool was primarily developed and tested for co-registration of laser profiles from the Lunar Orbiter Laser Altimeter (LOLA) with DTMs derived from the Lunar Reconnaissance Orbiter (LRO) Narrow Angle Camera (NAC) stereo images. Data sets can be co-registered with positional accuracy between 0.13 m and several meters depending on the pixel resolution and amount of laser shots, where rough surfaces typically result in more accurate co-registrations. Residual heights of the data sets are as small as 0.18 m. The software can be used to identify instrument misalignment, orbit errors, pointing jitter, or problems associated with reference frames being used. Also, assessments of DTM effective resolutions can be obtained. From the correct position between the two data sets, comparisons of surface morphology and roughness can be made at laser footprint- or DTM pixel-level. The precise co-registration allows us to carry out joint analysis of the data sets and ultimately to derive merged high-quality data products. Examples of matching other planetary data sets, like LOLA with LRO Wide Angle Camera (WAC) DTMs or Mars Orbiter Laser Altimeter (MOLA) with stereo models from the High Resolution Stereo Camera (HRSC) as well as Mercury Laser Altimeter (MLA) with Mercury Dual Imaging System (MDIS) are shown to demonstrate the broad science applications of the software tool.

  10. MREG V1.1 : a multi-scale image registration algorithm for SAR applications.

    SciTech Connect

    Eichel, Paul H.

    2013-08-01

    MREG V1.1 is the sixth generation SAR image registration algorithm developed by the Signal Processing&Technology Department for Synthetic Aperture Radar applications. Like its predecessor algorithm REGI, it employs a powerful iterative multi-scale paradigm to achieve the competing goals of sub-pixel registration accuracy and the ability to handle large initial offsets. Since it is not model based, it allows for high fidelity tracking of spatially varying terrain-induced misregistration. Since it does not rely on image domain phase, it is equally adept at coherent and noncoherent image registration. This document provides a brief history of the registration processors developed by Dept. 5962 leading up to MREG V1.1, a full description of the signal processing steps involved in the algorithm, and a user's manual with application specific recommendations for CCD, TwoColor MultiView, and SAR stereoscopy.

  11. 75 FR 48672 - Pesticides; Revised Fee Schedule for Registration Applications

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-11

    ... other regulatory decisions under FIFRA and the Federal Food, Drug, and Cosmetic Act (FFDCA). Section 33... Decision FY 11/12 Time Registration EPA No. CR No. Action (months) Service Fee FY 11/12 ($) R010 1 Food use\\1\\ 24 569,221 R020 2 Food use; reduced risk\\1\\ 18 569,221 R030 3 Food use; Experimental Use 24 629...

  12. Data Requirements for Pesticide Registration

    EPA Pesticide Factsheets

    In evaluating a pesticide registration application, we assess a wide variety of potential human health and environmental effects associated with use of the product. Learn about these data requirements.

  13. 40 CFR 165.65 - Registrants who distribute or sell pesticide products in refillable containers.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Registrants who distribute or sell pesticide products in refillable containers. 165.65 Section 165.65 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS PESTICIDE MANAGEMENT AND DISPOSAL Standards for Repackaging...

  14. 75 FR 8339 - Difenzoquat; Product Cancellation Order for Certain Pesticide Registrations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-24

    ... stakeholders including environmental, human health, and agricultural advocates; the chemical industry... Cancellations Registration Number Product Name Company 5481-536 Avenge Technical AMVAC Chemical Herbicide Corporation 5481-537 Avenge Wild Oat AMVAC Chemical Herbicide Corporation 5481-538 Avenge SG Wild Oat AMVAC...

  15. 76 FR 60025 - Product Cancellation Order for Certain Pesticide Registrations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-28

    ...). Table 2--Product Cancellations Containing Methyl bromide or Chloropicrin EPA Reg. No. Product name... Methyl Preplant Soil bromide Fumigant. 008536-00012 Methyl Bromide Methyl bromide 99.5%. CA900038 Methyl Bromide Methyl bromide 99.5%. CA900045 Methyl Bromide Methyl bromide 99.5%. CA910003 Methyl Bromide Methyl...

  16. 75 FR 35805 - Pesticide Product Registrations; Conditional Approvals

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-23

    ...-ZMIR245) in event MON 89034 corn (Office of Economic Cooperation and Development (OECD)) Unique Identifier... material necessary for their production (vector PV-ZMIR245) in event MON 89034 corn (OECD Unique Identifier... for their production (vector PV-ZMIR 245) in event MON 89034 corn (OECD Unique Identifier: MON-89034-3...

  17. Slice-to-volume parametric image registration models with applications to MRI-guided cardiac procedures

    NASA Astrophysics Data System (ADS)

    Ma, L. W. Lorraine; Ebrahimi, Mehran

    2017-03-01

    A mathematical formulation for intensity-based slice-to-volume registration is proposed. The approach is flexible and accommodates various regularization schemes, similarity measures, and optimizers. The framework is evaluated by registering 2D and 3D cardiac magnetic resonance (MR) images obtained in vivo, aimed at real- time MR-guided applications. Rigid-body and affine transformations are used to validate the parametric model. Target registration error (TRE), Jaccard, and Dice indices are used to evaluate the algorithm and demonstrate the accuracy of the registration scheme on both simulated and clinical data. Registration with the affine model appeared to be more robust than with the rigid model in controlled cases. By simply extending the rigid model to an affine model, alignment of the cardiac region generally improved, without the need for complex dissimilarity measures or regularizers.

  18. 40 CFR 79.10 - Application for registration by fuel manufacturer.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... in § 79.11. If the manufacturer produces more than one grade or brand of a designated fuel, a manufacturer may include more than one grade or brand in a single application, provided that the application includes all information required for registration of each such grade or brand by this part. Each...

  19. 37 CFR 2.133 - Amendment of application or registration during proceedings.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... approval of the Trademark Trial and Appeal Board, or upon motion granted by the Board. (b) If, in an inter partes proceeding, the Trademark Trial and Appeal Board finds that a party whose application or... restriction to the application or registration, the Board will allow the party time in which to file a motion...

  20. 37 CFR 2.133 - Amendment of application or registration during proceedings.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... approval of the Trademark Trial and Appeal Board, or upon motion granted by the Board. (b) If, in an inter partes proceeding, the Trademark Trial and Appeal Board finds that a party whose application or... restriction to the application or registration, the Board will allow the party time in which to file a motion...

  1. Automatic histology registration in application to x-ray modalities

    NASA Astrophysics Data System (ADS)

    Chicherova, Natalia; Hieber, Simone E.; Schulz, Georg; Khimchenko, Anna; Bikis, Christos; Cattin, Philippe C.; Müller, Bert

    2016-10-01

    Registration of microscope images to Computed Tomography (CT) 3D volumes is a challenging task because it requires not only multi-modal similarity measure but also 2D-3D or slice-to-volume correspondence. This type of registration is usually done manually which is very time-consuming and prone to errors. Recently we have developed the first automatic approach to localize histological sections in μCT data of a jaw bone. The median distance between the automatically found slices and the ground truth was below 35 μm. Here we explore the limitations of the method by applying it to three tomography datasets acquired with grating interferometry, laboratory-based μCT and single-distance phase retrieval. Moreover, we compare the performance of three feature detectors in the proposed framework, i.e. Speeded Up Robust Features (SURF), Scale Invariant Feature Transform (SIFT) and Affine SIFT (ASIFT). Our results show that all the feature detectors performed significantly better on the grating interferometry dataset than on other modalities. The median accuracy for the vertical position was 0.06 mm. Across the feature detector types the smallest error was achieved by the SURF-based feature detector (0.29 mm). Furthermore, the SURF-based method was computationally the most efficient. Thus, we recommend to use the SURF feature detector for the proposed framework.

  2. 75 FR 57019 - Pesticide Product Registrations; Conditional Approval

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-17

    ... affected by this action if you are an agricultural producer, food manufacturer, or pesticide manufacturer... production (NAICS code 112). Food manufacturing (NAICS code 311). Pesticide manufacturing (NAICS code 32532... unreasonable adverse effects; and that use of the pesticide is in the public interest. The Agency has...

  3. 76 FR 10587 - Product Cancellation Order for Certain Pesticide Registrations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-25

    ... Corps, P.O. Box 2200, West Lafayette, IN 47996- 2200. 8329 Clarke Mosquito Control Products, Inc. , P.O... Corps, P.O. Box FL970010, HI910006. 2200, West Lafayette, IN 47996- 2200. FL070008 Clarke Mosquito... from the American Mosquito Control Association and the IR-4 Project on temephos. Both organizations...

  4. Deformable 3D-2D registration for CT and its application to low dose tomographic fluoroscopy.

    PubMed

    Flach, Barbara; Brehm, Marcus; Sawall, Stefan; Kachelrieß, Marc

    2014-12-21

    Many applications in medical imaging include image registration for matching of images from the same or different modalities. In the case of full data sampling, the respective reconstructed images are usually of such a good image quality that standard deformable volume-to-volume (3D-3D) registration approaches can be applied. But research in temporal-correlated image reconstruction and dose reductions increases the number of cases where rawdata are available from only few projection angles. Here, deteriorated image quality leads to non-acceptable deformable volume-to-volume registration results. Therefore a registration approach is required that is robust against a decreasing number of projections defining the target position. We propose a deformable volume-to-rawdata (3D-2D) registration method that aims at finding a displacement vector field maximizing the alignment of a CT volume and the acquired rawdata based on the sum of squared differences in rawdata domain. The registration is constrained by a regularization term in accordance with a fluid-based diffusion. Both cost function components, the rawdata fidelity and the regularization term, are optimized in an alternating manner. The matching criterion is optimized by a conjugate gradient descent for nonlinear functions, while the regularization is realized by convolution of the vector fields with Gaussian kernels. We validate the proposed method and compare it to the demons algorithm, a well-known 3D-3D registration method. The comparison is done for a range of 4-60 target projections using datasets from low dose tomographic fluoroscopy as an application example. The results show a high correlation to the ground truth target position without introducing artifacts even in the case of very few projections. In particular the matching in the rawdata domain is improved compared to the 3D-3D registration for the investigated range. The proposed volume-to-rawdata registration increases the robustness regarding sparse

  5. Deformable 3D-2D registration for CT and its application to low dose tomographic fluoroscopy

    NASA Astrophysics Data System (ADS)

    Flach, Barbara; Brehm, Marcus; Sawall, Stefan; Kachelrieß, Marc

    2014-12-01

    Many applications in medical imaging include image registration for matching of images from the same or different modalities. In the case of full data sampling, the respective reconstructed images are usually of such a good image quality that standard deformable volume-to-volume (3D-3D) registration approaches can be applied. But research in temporal-correlated image reconstruction and dose reductions increases the number of cases where rawdata are available from only few projection angles. Here, deteriorated image quality leads to non-acceptable deformable volume-to-volume registration results. Therefore a registration approach is required that is robust against a decreasing number of projections defining the target position. We propose a deformable volume-to-rawdata (3D-2D) registration method that aims at finding a displacement vector field maximizing the alignment of a CT volume and the acquired rawdata based on the sum of squared differences in rawdata domain. The registration is constrained by a regularization term in accordance with a fluid-based diffusion. Both cost function components, the rawdata fidelity and the regularization term, are optimized in an alternating manner. The matching criterion is optimized by a conjugate gradient descent for nonlinear functions, while the regularization is realized by convolution of the vector fields with Gaussian kernels. We validate the proposed method and compare it to the demons algorithm, a well-known 3D-3D registration method. The comparison is done for a range of 4-60 target projections using datasets from low dose tomographic fluoroscopy as an application example. The results show a high correlation to the ground truth target position without introducing artifacts even in the case of very few projections. In particular the matching in the rawdata domain is improved compared to the 3D-3D registration for the investigated range. The proposed volume-to-rawdata registration increases the robustness regarding sparse

  6. A Model-Driven, Science Data Product Registration Service

    NASA Astrophysics Data System (ADS)

    Hardman, S.; Ramirez, P.; Hughes, J. S.; Joyner, R.; Cayanan, M.; Lee, H.; Crichton, D. J.

    2011-12-01

    artifacts above as well as offering the flexibility to support customer-defined artifacts. Key features for the Registry Service include: - Model-based configuration specifying customer-defined artifact types, metadata attributes to capture for each artifact type, supported associations and classification schemes. - A REST-based external interface that is accessible via the Hypertext Transfer Protocol (HTTP). - Federation of Registry Service instances allowing associations between registered artifacts across registries as well as queries for artifacts across those same registries. A federation also enables features such as replication and synchronization if desired for a given deployment. In addition to its use as a core component of the PDS, the generic implementation of the Registry Service facilitates its applicability as a core component in any science data archive or science data system.

  7. Registration methods for nonblind watermark detection in digital cinema applications

    NASA Astrophysics Data System (ADS)

    Nguyen, Philippe; Balter, Raphaele; Montfort, Nicolas; Baudry, Severine

    2003-06-01

    Digital watermarking may be used to enforce copyright protection of digital cinema, by embedding in each projected movie an unique identifier (fingerprint). By identifying the source of illegal copies, watermarking will thus incite movie theatre managers to enforce copyright protection, in particular by preventing people from coming in with a handy cam. We propose here a non-blind watermark method to improve the watermark detection on very impaired sequences. We first present a study on the picture impairments caused by the projection on a screen, then acquisition with a handy cam. We show that images undergo geometric deformations, which are fully described by a projective geometry model. The sequence also undergoes spatial and temporal luminance variation. Based on this study and on the impairments models which follow, we propose a method to match the retrieved sequence to the original one. First, temporal registration is performed by comparing the average luminance variation on both sequences. To compensate for geometric transformations, we used paired points from both sequences, obtained by applying a feature points detector. The matching of the feature points then enables to retrieve the geometric transform parameters. Tests show that the watermark retrieval on rectified sequences is greatly improved.

  8. 76 FR 7102 - Simplified Network Application Processing System, On-line Registration and Account Maintenance

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-09

    ... Bureau of Industry and Security 15 CFR Part 748 RIN 0694-AE98 Simplified Network Application Processing System, On-line Registration and Account Maintenance AGENCY: Bureau of Industry and Security, Commerce. ACTION: Final rule. SUMMARY: The Bureau of Industry and Security (BIS) amends the Export...

  9. 42 CFR 493.55 - Application for registration certificate and certificate of accreditation.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ..., health screening fairs, or other temporary testing locations may be covered under the certificate of the... 42 Public Health 5 2011-10-01 2011-10-01 false Application for registration certificate and certificate of accreditation. 493.55 Section 493.55 Public Health CENTERS FOR MEDICARE & MEDICAID...

  10. 42 CFR 493.43 - Application for registration certificate, certificate for provider-performed microscopy (PPM...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... to testing site, such as mobile units providing laboratory testing, health screening fairs, or other... 42 Public Health 5 2010-10-01 2010-10-01 false Application for registration certificate... 493.43 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN...

  11. 42 CFR 493.55 - Application for registration certificate and certificate of accreditation.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ..., health screening fairs, or other temporary testing locations may be covered under the certificate of the... 42 Public Health 5 2010-10-01 2010-10-01 false Application for registration certificate and certificate of accreditation. 493.55 Section 493.55 Public Health CENTERS FOR MEDICARE & MEDICAID...

  12. 42 CFR 493.43 - Application for registration certificate, certificate for provider-performed microscopy (PPM...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... to testing site, such as mobile units providing laboratory testing, health screening fairs, or other... 42 Public Health 5 2011-10-01 2011-10-01 false Application for registration certificate... 493.43 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN...

  13. 78 FR 46622 - Application of Topaz Exchange, LLC for Registration as a National Securities Exchange; Findings...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-01

    ... From the Federal Register Online via the Government Publishing Office SECURITIES AND EXCHANGE COMMISSION Application of Topaz Exchange, LLC for Registration as a National Securities Exchange; Findings, Opinion, and Order of the Commission July 26, 2013. I. Introduction On July 3, 2012, Topaz Exchange, LLC (``Topaz Exchange'' or ``Exchange'')...

  14. 17 CFR 242.609 - Registration of securities information processors: form of application and amendments.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... application for the registration of a securities information processor shall be filed on Form SIP (§ 249.1001... reported in items 1-13 or item 21 of Form SIP or in any amendment thereto is or becomes inaccurate for any... shall promptly file an amendment on Form SIP correcting such information. (c) The Commission, upon...

  15. 17 CFR 242.609 - Registration of securities information processors: form of application and amendments.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... application for the registration of a securities information processor shall be filed on Form SIP (§ 249.1001... reported in items 1-13 or item 21 of Form SIP or in any amendment thereto is or becomes inaccurate for any... shall promptly file an amendment on Form SIP correcting such information. (c) The Commission, upon...

  16. 17 CFR Appendix to Part 39 - Form DCO Derivatives Clearing Organization Application for Registrations

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 17 Commodity and Securities Exchanges 1 2012-04-01 2012-04-01 false Form DCO Derivatives Clearing... FUTURES TRADING COMMISSION DERIVATIVES CLEARING ORGANIZATIONS Pt. 39, App. Appendix to Part 39—Form DCO Derivatives Clearing Organization Application for Registrations ER08NO11.001 ER08NO11.002...

  17. 17 CFR Appendix to Part 39 - Form DCO Derivatives Clearing Organization Application for Registrations

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 17 Commodity and Securities Exchanges 1 2013-04-01 2013-04-01 false Form DCO Derivatives Clearing... FUTURES TRADING COMMISSION DERIVATIVES CLEARING ORGANIZATIONS Pt. 39, App. Appendix to Part 39—Form DCO Derivatives Clearing Organization Application for Registrations ER08NO11.001 ER08NO11.002...

  18. 37 CFR 3.25 - Recording requirements for trademark applications and registrations.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2011-07-01 2011-07-01 false Recording requirements for trademark applications and registrations. 3.25 Section 3.25 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF COMMERCE GENERAL ASSIGNMENT, RECORDING AND RIGHTS OF...

  19. 37 CFR 2.194 - Identification of trademark application or registration.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Identification of trademark application or registration. 2.194 Section 2.194 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF COMMERCE RULES OF PRACTICE IN TRADEMARK CASES General Information and...

  20. 37 CFR 3.25 - Recording requirements for trademark applications and registrations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Recording requirements for trademark applications and registrations. 3.25 Section 3.25 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF COMMERCE GENERAL ASSIGNMENT, RECORDING AND RIGHTS OF...

  1. 37 CFR 2.194 - Identification of trademark application or registration.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2011-07-01 2011-07-01 false Identification of trademark application or registration. 2.194 Section 2.194 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF COMMERCE RULES OF PRACTICE IN TRADEMARK CASES General Information and...

  2. Precision of image-based registration for intraoperative navigation in the presence of metal artifacts: Application to corrective osteotomy surgery.

    PubMed

    Dobbe, J G G; Curnier, F; Rondeau, X; Streekstra, G J

    2015-06-01

    Navigation for corrective osteotomy surgery requires patient-to-image registration. When registration is based on intraoperative 3-D cone-beam CT (CBCT) imaging, metal landmarks may be used that deteriorate image quality. This study investigates whether metal artifacts influence the precision of image-to-patient registration, either with or without intermediate user intervention during the registration procedure, in an application for corrective osteotomy of the distal radius. A series of 3-D CBCT scans is made of a cadaver arm with and without metal landmarks. Metal artifact reduction (MAR) based on inpainting techniques is used to improve 3-D CBCT images hampered by metal artifacts. This provides three sets of images (with metal, with MAR, and without metal), which enable investigating the differences in precision of intraoperative registration. Gray-level based point-to-image registration showed a better correlation coefficient if intraoperative images with MAR are used, indicating a better image similarity. The precision of registration without intermediate user intervention during the registration procedure, expressed as the residual angulation and displacement error after repetitive registration was very low and showed no improvement when MAR was used. By adding intermediate user intervention to the registration procedure however, precision was very high but was not affected by the presence of metal artifacts in the specific application.

  3. GPU-accelerated elastic 3D image registration for intra-surgical applications.

    PubMed

    Ruijters, Daniel; ter Haar Romeny, Bart M; Suetens, Paul

    2011-08-01

    Local motion within intra-patient biomedical images can be compensated by using elastic image registration. The application of B-spline based elastic registration during interventional treatment is seriously hampered by its considerable computation time. The graphics processing unit (GPU) can be used to accelerate the calculation of such elastic registrations by using its parallel processing power, and by employing the hardwired tri-linear interpolation capabilities in order to efficiently perform the cubic B-spline evaluation. In this article it is shown that the similarity measure and its derivatives also can be calculated on the GPU, using a two pass approach. On average a speedup factor 50 compared to a straight-forward CPU implementation was reached.

  4. Sensor-agnostic photogrammetric image registration with applications to population modeling

    SciTech Connect

    White, Devin A; Moehl, Jessica J

    2016-01-01

    Photogrammetric registration of airborne and spaceborne imagery is a crucial prerequisite to many data fusion tasks. While embedded sensor models provide a rough geolocation estimate, these metadata may be incomplete or imprecise. Manual solutions are appropriate for small-scale projects, but for rapid streams of cross-modal, multi-sensor, multi-temporal imagery with varying metadata standards, an automated approach is required. We present a high-performance image registration workflow to address this need. This paper outlines the core development concepts and demonstrates its utility with respect to the 2016 data fusion contest imagery. In particular, Iris ultra-HD video is georeferenced to the Earth surface via registration to DEIMOS-2 imagery, which serves as a trusted control source. Geolocation provides opportunity to augment the video with spatial context, stereo-derived disparity, spectral sensitivity, change detection, and numerous ancillary geospatial layers. We conclude by leveraging these derivative data layers towards one such fusion application: population distribution modeling.

  5. 14 CFR 47.15 - Registration number.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 1 2013-01-01 2013-01-01 false Registration number. 47.15 Section 47.15... REGISTRATION General § 47.15 Registration number. (a) Number required. An applicant for aircraft registration must place a U.S. registration number (registration mark) on the Aircraft Registration Application, AC...

  6. 14 CFR 47.15 - Registration number.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 1 2012-01-01 2012-01-01 false Registration number. 47.15 Section 47.15... REGISTRATION General § 47.15 Registration number. (a) Number required. An applicant for aircraft registration must place a U.S. registration number (registration mark) on the Aircraft Registration Application, AC...

  7. 14 CFR 47.15 - Registration number.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Registration number. 47.15 Section 47.15... REGISTRATION General § 47.15 Registration number. (a) Number required. An applicant for aircraft registration must place a U.S. registration number (registration mark) on the Aircraft Registration Application,...

  8. Local Metric Learning in 2D/3D Deformable Registration With Application in the Abdomen

    PubMed Central

    Chou, Chen-Rui; Mageras, Gig; Pizer, Stephen

    2015-01-01

    In image-guided radiotherapy (IGRT) of disease sites subject to respiratory motion, soft tissue deformations can affect localization accuracy. We describe the application of a method of 2D/3D deformable registration to soft tissue localization in abdomen. The method, called registration efficiency and accuracy through learning a metric on shape (REALMS), is designed to support real-time IGRT. In a previously developed version of REALMS, the method interpolated 3D deformation parameters for any credible deformation in a deformation space using a single globally-trained Riemannian metric for each parameter. We propose a refinement of the method in which the metric is trained over a particular region of the deformation space, such that interpolation accuracy within that region is improved. We report on the application of the proposed algorithm to IGRT in abdominal disease sites, which is more challenging than in lung because of low intensity contrast and nonrespiratory deformation. We introduce a rigid translation vector to compensate for nonrespiratory deformation, and design a special region-of-interest around fiducial markers implanted near the tumor to produce a more reliable registration. Both synthetic data and actual data tests on abdominal datasets show that the localized approach achieves more accurate 2D/3D deformable registration than the global approach. PMID:24771575

  9. 40 CFR 152.113 - Approval of registration under FIFRA sec. 3(c)(7)-Products that do not contain a new active...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... available an effective alternative registered pesticide which does not meet the risk criteria associated... of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS PESTICIDE REGISTRATION... registration of a pesticide product, each of whose active ingredients is contained in one or more...

  10. Antimicrobial resistance and the guidelines of the International Cooperation on Harmonisation of Technical Requirements for Registration of Veterinary Medicinal Products (VICH).

    PubMed

    Marion, H

    2012-04-01

    The International Cooperation on Harmonisation of Technical Requirements for Registration of Veterinary Medicinal Products (VICH) is an international tripartite cooperation programme that brings together regulatory authorities and industry representatives from the European Union, Japan and the United States, with Australia, New Zealand and Canada as observers. VICH aims to improve international coordination and cooperation to achieve greater harmonisation of the requirements for veterinary product registration in the regions concerned. VICH develops harmonised data requirements, i.e., standards for the scientific studies on quality, safety and efficacy that are required to obtain a marketing authorisation for a veterinary medicinal product. It does this by publishing guidelines that provide uniform and consistent guidance for sponsors to follow in developing data for application dossiers as well as for post-marketing safety monitoring of veterinary medicinal products. Of the 49 VICH guidelines that have been developed so far, two guidelines in particular address issues related to antimicrobial resistance.

  11. 75 FR 81849 - Office of the Attorney General; Applicability of the Sex Offender Registration and Notification Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-29

    ... Order No. 3239-2010] RIN 1105-AB22 Office of the Attorney General; Applicability of the Sex Offender... the Sex Offender Registration and Notification Act, title I of Public Law 109-248, apply to all sex offenders, including sex offenders convicted of the offense for which registration is required before the...

  12. Detection of Geometric Keypoints and its Application to Point Cloud Coarse Registration

    NASA Astrophysics Data System (ADS)

    Bueno, M.; Martínez-Sánchez, J.; González-Jorge, H.; Lorenzo, H.

    2016-06-01

    Acquisition of large scale scenes, frequently, involves the storage of large amount of data, and also, the placement of several scan positions to obtain a complete object. This leads to a situation with a different coordinate system in each scan position. Thus, a preprocessing of it to obtain a common reference frame is usually needed before analysing it. Automatic point cloud registration without locating artificial markers is a challenging field of study. The registration of millions or billions of points is a demanding task. Subsampling the original data usually solves the situation, at the cost of reducing the precision of the final registration. In this work, a study of the subsampling via the detection of keypoints and its capability to apply in coarse alignment is performed. The keypoints obtained are based on geometric features of each individual point, and are extracted using the Difference of Gaussians approach over 3D data. The descriptors include features as eigenentropy, change of curvature and planarity. Experiments demonstrate that the coarse alignment, obtained through these keypoints outperforms the coarse registration root mean squared error of an operator by 3 - 5 cm. The applicability of these keypoints is tested and verified in five different case studies.

  13. Cortical Correspondence via Sulcal Curve-Constrained Spherical Registration with Application to Macaque Studies.

    PubMed

    Lyu, Ilwoo; Kim, Sun Hyung; Seong, Joon-Kyung; Yoo, Sang Wook; Evans, Alan C; Shi, Yundi; Sanchez, Mar; Niethammer, Marc; Styner, Martin

    2013-03-13

    In this work, we present a novel cortical correspondence method with application to the macaque brain. The correspondence method is based on sulcal curve constraints on a spherical deformable registration using spherical harmonics to parameterize the spherical deformation. Starting from structural MR images, we first apply existing preprocessing steps: brain tissue segmentation using the Automatic Brain Classification tool (ABC), as well as cortical surface reconstruction and spherical parametrization of the cortical surface via Constrained Laplacian-based Automated Segmentation with Proximities (CLASP). Then, initial correspondence between two cortical surfaces is automatically determined by a curve labeling method using sulcal landmarks extracted along sulcal fundic regions. Since the initial correspondence is limited to sulcal regions, we use spherical harmonics to extrapolate and regularize this correspondence to the entire cortical surface. To further improve the correspondence, we compute a spherical registration that optimizes the spherical harmonic parameterized deformation using a metric that incorporates the error over the sulcal landmarks as well as the normalized cross correlation of sulcal depth maps over the whole cortical surface. For evaluation, a normal 18-months-old macaque brain (for both left and right hemispheres) was matched to a prior macaque brain template with 9 manually labeled, major sulcal curves. The results show successful registration using the proposed registration approach. Evaluation results for optimal parameter settings are presented as well.

  14. A complete software application for automatic registration of x-ray mammography and magnetic resonance images

    SciTech Connect

    Solves-Llorens, J. A.; Rupérez, M. J. Monserrat, C.; Lloret, M.

    2014-08-15

    Purpose: This work presents a complete and automatic software application to aid radiologists in breast cancer diagnosis. The application is a fully automated method that performs a complete registration of magnetic resonance (MR) images and x-ray (XR) images in both directions (from MR to XR and from XR to MR) and for both x-ray mammograms, craniocaudal (CC), and mediolateral oblique (MLO). This new approximation allows radiologists to mark points in the MR images and, without any manual intervention, it provides their corresponding points in both types of XR mammograms and vice versa. Methods: The application automatically segments magnetic resonance images and x-ray images using the C-Means method and the Otsu method, respectively. It compresses the magnetic resonance images in both directions, CC and MLO, using a biomechanical model of the breast that distinguishes the specific biomechanical behavior of each one of its three tissues (skin, fat, and glandular tissue) separately. It makes a projection of both compressions and registers them with the original XR images using affine transformations and nonrigid registration methods. Results: The application has been validated by two expert radiologists. This was carried out through a quantitative validation on 14 data sets in which the Euclidean distance between points marked by the radiologists and the corresponding points obtained by the application were measured. The results showed a mean error of 4.2 ± 1.9 mm for the MRI to CC registration, 4.8 ± 1.3 mm for the MRI to MLO registration, and 4.1 ± 1.3 mm for the CC and MLO to MRI registration. Conclusions: A complete software application that automatically registers XR and MR images of the breast has been implemented. The application permits radiologists to estimate the position of a lesion that is suspected of being a tumor in an imaging modality based on its position in another different modality with a clinically acceptable error. The results show that the

  15. A complete software application for automatic registration of x-ray mammography and magnetic resonance images.

    PubMed

    Solves-Llorens, J A; Rupérez, M J; Monserrat, C; Feliu, E; García, M; Lloret, M

    2014-08-01

    This work presents a complete and automatic software application to aid radiologists in breast cancer diagnosis. The application is a fully automated method that performs a complete registration of magnetic resonance (MR) images and x-ray (XR) images in both directions (from MR to XR and from XR to MR) and for both x-ray mammograms, craniocaudal (CC), and mediolateral oblique (MLO). This new approximation allows radiologists to mark points in the MR images and, without any manual intervention, it provides their corresponding points in both types of XR mammograms and vice versa. The application automatically segments magnetic resonance images and x-ray images using the C-Means method and the Otsu method, respectively. It compresses the magnetic resonance images in both directions, CC and MLO, using a biomechanical model of the breast that distinguishes the specific biomechanical behavior of each one of its three tissues (skin, fat, and glandular tissue) separately. It makes a projection of both compressions and registers them with the original XR images using affine transformations and nonrigid registration methods. The application has been validated by two expert radiologists. This was carried out through a quantitative validation on 14 data sets in which the Euclidean distance between points marked by the radiologists and the corresponding points obtained by the application were measured. The results showed a mean error of 4.2 ± 1.9 mm for the MRI to CC registration, 4.8 ± 1.3 mm for the MRI to MLO registration, and 4.1 ± 1.3 mm for the CC and MLO to MRI registration. A complete software application that automatically registers XR and MR images of the breast has been implemented. The application permits radiologists to estimate the position of a lesion that is suspected of being a tumor in an imaging modality based on its position in another different modality with a clinically acceptable error. The results show that the application can accelerate the

  16. Robust feature estimation by non-rigid hierarchical image registration and its application in disparity measurement

    NASA Astrophysics Data System (ADS)

    Badshah, Amir; Choudhry, Aadil Jaleel; Ullah, Shan

    2017-03-01

    Industries are moving towards automation in order to increase productivity and ensure quality. Variety of electronic and electromagnetic systems are being employed to assist human operator in fast and accurate quality inspection of products. Majority of these systems are equipped with cameras and rely on diverse image processing algorithms. Information is lost in 2D image, therefore acquiring accurate 3D data from 2D images is an open issue. FAST, SURF and SIFT are well-known spatial domain techniques for features extraction and henceforth image registration to find correspondence between images. The efficiency of these methods is measured in terms of the number of perfect matches found. A novel fast and robust technique for stereo-image processing is proposed. It is based on non-rigid registration using modified normalized phase correlation. The proposed method registers two images in hierarchical fashion using quad-tree structure. The registration process works through global to local level resulting in robust matches even in presence of blur and noise. The computed matches can further be utilized to determine disparity and depth for industrial product inspection. The same can be used in driver assistance systems. The preliminary tests on Middlebury dataset produced satisfactory results. The execution time for a 413 x 370 stereo-pair is 500ms approximately on a low cost DSP.

  17. Registration requirements for importers and manufacturers of prescription drug products containing ephedrine, pseudoephedrine, or phenylpropanolamine. Final rule.

    PubMed

    2010-02-01

    The Drug Enforcement Administration (DEA) is amending its registration regulations to ensure that a registration is obtained for every location where ephedrine, pseudoephedrine, or phenylpropanolamine, or drug products containing one of these chemicals, are imported or manufactured. These amendments will make it possible to establish the system of quotas and assessment of annual needs for the importation and manufacture of these chemicals that Congress mandated in the Combat Methamphetamine Epidemic Act of 2005.

  18. Using an Android application to assess registration strategies in open hepatic procedures: a planning and simulation tool

    NASA Astrophysics Data System (ADS)

    Doss, Derek J.; Heiselman, Jon S.; Collins, Jarrod A.; Weis, Jared A.; Clements, Logan W.; Geevarghese, Sunil K.; Miga, Michael I.

    2017-03-01

    Sparse surface digitization with an optically tracked stylus for use in an organ surface-based image-to-physical registration is an established approach for image-guided open liver surgery procedures. However, variability in sparse data collections during open hepatic procedures can produce disparity in registration alignments. In part, this variability arises from inconsistencies with the patterns and fidelity of collected intraoperative data. The liver lacks distinct landmarks and experiences considerable soft tissue deformation. Furthermore, data coverage of the organ is often incomplete or unevenly distributed. While more robust feature-based registration methodologies have been developed for image-guided liver surgery, it is still unclear how variation in sparse intraoperative data affects registration. In this work, we have developed an application to allow surgeons to study the performance of surface digitization patterns on registration. Given the intrinsic nature of soft-tissue, we incorporate realistic organ deformation when assessing fidelity of a rigid registration methodology. We report the construction of our application and preliminary registration results using four participants. Our preliminary results indicate that registration quality improves as users acquire more experience selecting patterns of sparse intraoperative surface data.

  19. Learning from experience: improving the process of internationally educated nurses' application for registration - a study protocol.

    PubMed

    Giblin, Cathy; Lemermeyer, Gillian; Cummings, Greta; Wang, Mengzhe; Kwan, Jennifer Anne

    2016-03-01

    This study aims to improve the efficiency of the application for registration process for internationally educated nurses seeking licensure to practice. The licensure and employment of internationally educated nurses has been one strategy to address the global nursing shortage. However, little is known about which application characteristics relate to success in obtaining licensure. This project uses evidence from a retrospective statistical analysis of four years of internationally educated nurse application data to inform the development and implementation of changes to policies and practices at the College and Association of Registered Nurses of Alberta. Analysis of application data will also be conducted to evaluate the impact of the changes on outcomes and timelines. The project encompasses four phases, with funding from Health Canada's Internationally Educated Health Professionals Initiative approved in March 2011. Phase One focuses on a statistical analysis of application data to identify characteristics associated with success in the application process and quantify timelines for the phases of the process. The resulting knowledge will inform Phase Two, the development and implementation of policy and practice changes. Further analysis will be completed in Phase Three, comparing outcomes and timelines between pre- and postimplementation data using statistical analyses and exemplar-based statistics. Phase Four will focus on dissemination and knowledge transfer, potentially leading to further changes. Findings, policy and practice adaptations and implementation evaluation will provide evidence about the internationally educated nurse application for registration process to Registered Nurse regulators, educational institutions, internationally educated nurses, employers and governments. © 2015 John Wiley & Sons Ltd.

  20. PR notice 87-6. Notice to manufacturers, formulators, procedures, and registrants of pesticide products

    SciTech Connect

    Not Available

    1987-05-01

    The document is one in the series of Pesticide Regulatory Notices, usually called PR Notices, which supplement the laws and regulations governing pesticide regulation in the US. These notices clarify, interpret and explain regulatory requirements and policies. They are directed at pesticide registrants and other parties interested in detailed procedures of regulation. This notice announces certain policies designed to reduce the potential for adverse effects from the use of pesticide products containing toxic inert ingredients. The agency is encouraging the use of the least toxic inert ingredient available and requiring the development of data necessary to determine the conditions of safe use of products containing toxic inert ingredients. In support of these policies, the Agency has categorized inert ingredients according to toxicity.

  1. 17 CFR 240.15b11-1 - Registration by notice of security futures product broker-dealers.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... security futures product broker-dealers. 240.15b11-1 Section 240.15b11-1 Commodity and Securities Exchanges... § 240.15b11-1 Registration by notice of security futures product broker-dealers. (a) A broker or dealer...) Is registered with the Commodity Futures Trading Commission as a futures commission merchant or an...

  2. Probability density estimation using isocontours and isosurfaces: applications to information-theoretic image registration.

    PubMed

    Rajwade, Ajit; Banerjee, Arunava; Rangarajan, Anand

    2009-03-01

    We present a new, geometric approach for determining the probability density of the intensity values in an image. We drop the notion of an image as a set of discrete pixels, and assume a piecewise-continuous representation. The probability density can then be regarded as being proportional to the area between two nearby isocontours of the image surface. Our paper extends this idea to joint densities of image pairs. We demonstrate the application of our method to affine registration between two or more images using information theoretic measures such as mutual information. We show cases where our method outperforms existing methods such as simple histograms, histograms with partial volume interpolation, Parzen windows, etc. under fine intensity quantization for affine image registration under significant image noise. Furthermore, we demonstrate results on simultaneous registration of multiple images, as well as for pairs of volume datasets, and show some theoretical properties of our density estimator. Our approach requires the selection of only an image interpolant. The method neither requires any kind of kernel functions (as in Parzen windows) which are unrelated to the structure of the image in itself, nor does it rely on any form of sampling for density estimation.

  3. Probability Density Estimation Using Isocontours and Isosurfaces: Application to Information-Theoretic Image Registration

    PubMed Central

    Rajwade, Ajit; Banerjee, Arunava; Rangarajan, Anand

    2010-01-01

    We present a new geometric approach for determining the probability density of the intensity values in an image. We drop the notion of an image as a set of discrete pixels and assume a piecewise-continuous representation. The probability density can then be regarded as being proportional to the area between two nearby isocontours of the image surface. Our paper extends this idea to joint densities of image pairs. We demonstrate the application of our method to affine registration between two or more images using information-theoretic measures such as mutual information. We show cases where our method outperforms existing methods such as simple histograms, histograms with partial volume interpolation, Parzen windows, etc., under fine intensity quantization for affine image registration under significant image noise. Furthermore, we demonstrate results on simultaneous registration of multiple images, as well as for pairs of volume data sets, and show some theoretical properties of our density estimator. Our approach requires the selection of only an image interpolant. The method neither requires any kind of kernel functions (as in Parzen windows), which are unrelated to the structure of the image in itself, nor does it rely on any form of sampling for density estimation. PMID:19147876

  4. Image registration via level-set motion: applications to atlas-based segmentation.

    PubMed

    Vemuri, B C; Ye, J; Chen, Y; Leonard, C M

    2003-03-01

    Image registration is an often encountered problem in various fields including medical imaging, computer vision and image processing. Numerous algorithms for registering image data have been reported in these areas. In this paper, we present a novel curve evolution approach expressed in a level-set framework to achieve image intensity morphing and a simple non-linear PDE for the corresponding coordinate registration. The key features of the intensity morphing model are that (a) it is very fast and (b) existence and uniqueness of the solution for the evolution model are established in a Sobolev space as opposed to using viscosity methods. The salient features of the coordinate registration model are its simplicity and computational efficiency. The intensity morph is easily achieved via evolving level-sets of one image into the level-sets of the other. To explicitly estimate the coordinate transformation between the images, we derive a non-linear PDE-based motion model which can be solved very efficiently. We demonstrate the performance of our algorithm on a variety of images including synthetic and real data. As an application of the PDE-based motion model, atlas based segmentation of hippocampal shape from several MR brain scans is depicted. In each of these experiments, automated hippocampal shape recovery results are validated via manual "expert" segmentations.

  5. Study on requirements of bioequivalence for registration of pharmaceutical products in USA, Europe and Canada.

    PubMed

    Galgatte, Upendra C; Jamdade, Vijay R; Aute, Pravin P; Chaudhari, Pravin D

    2014-11-01

    The present study was aimed to study the requirements of bioequivalence for the registration of pharmaceutical products in the USA, Europe and Canada. Before going into bioequivalence studies it is essential for the pharmaceutical industry to study the guidelines of bioequivalence for the respective country where the industry wants to market its products and thus enter into generic market. This study reviews the requirements of bioequivalence with study parameters such as study design, fasting or fed state studies, volunteers recruitment, study dose, sampling points, analytical method validation parameters, moieties to be measured in plasma, pharmacokinetic parameters, criteria for bioequivalence, GCP requirements etc, which are needed for the pharmaceutical industry to carry out bioequivalence studies and to file ANDA. Test products and reference products are needed for this study. Test products are usually manufactured by a sponsor and reference products are provided by the government laboratories of the respective countries. Sampling points also vary with respect to the regulatory guidelines of these countries. All these countries follow ICH GCP guidelines. The criterion of bioequivalence for these countries is 90% CI 80-125% for C max, AUC t , AUC0-∞.

  6. Application of a reduced area electrical test pattern to precise pattern registration measurements

    NASA Astrophysics Data System (ADS)

    Rominger, James P.

    1991-03-01

    A new reduced area electrically probed registration measurement pattern is described. The pattern is compatible with the Prometrix data acquisition and analysis system, and offers advantages over standard patterns in terms of patten area and versatility of use. The results of the application of the pattern to the measurement of reticle and stepper overlay are presented. With careful analysis of the data, inter- and intrafield reticle overlay errors are determined. Horizontal and vertical measurements of pattern placement within a single field and between fields showed an accuracy of greater than 67 nm and a repeatability of better than 14 nm (3 sigma).

  7. Detection of patient setup errors with a portal image - DRR registration software application.

    PubMed

    Sutherland, Kenneth; Ishikawa, Masayori; Bengua, Gerard; Ito, Yoichi M; Miyamoto, Yoshiko; Shirato, Hiroki

    2011-02-18

    The purpose of this study was to evaluate a custom portal image - digitally reconstructed radiograph (DRR) registration software application. The software works by transforming the portal image into the coordinate space of the DRR image using three control points placed on each image by the user, and displaying the fused image. In order to test statistically that the software actually improves setup error estimation, an intra- and interobserver phantom study was performed. Portal images of anthropomorphic thoracic and pelvis phantoms with virtually placed irradiation fields at known setup errors were prepared. A group of five doctors was first asked to estimate the setup errors by examining the portal and DRR image side-by-side, not using the software. A second group of four technicians then estimated the same set of images using the registration software. These two groups of human subjects were then compared with an auto-registration feature of the software, which is based on the mutual information between the portal and DRR images. For the thoracic case, the average distance between the actual setup error and the estimated error was 4.3 ± 3.0 mm for doctors using the side-by-side method, 2.1 ± 2.4 mm for technicians using the registration method, and 0.8 ± 0.4mm for the automatic algorithm. For the pelvis case, the average distance between the actual setup error and estimated error was 2.0 ± 0.5 mm for the doctors using the side-by-side method, 2.5 ± 0.4 mm for technicians using the registration method, and 2.0 ± 1.0 mm for the automatic algorithm. The ability of humans to estimate offset values improved statistically using our software for the chest phantom that we tested. Setup error estimation was further improved using our automatic error estimation algorithm. Estimations were not statistically different for the pelvis case. Consistency improved using the software for both the chest and pelvis phantoms. We also tested the automatic algorithm with a

  8. Nattokinase: production and application.

    PubMed

    Dabbagh, Fatemeh; Negahdaripour, Manica; Berenjian, Aydin; Behfar, Abdolazim; Mohammadi, Fatemeh; Zamani, Mozhdeh; Irajie, Cambyz; Ghasemi, Younes

    2014-11-01

    Nattokinase (NK, also known as subtilisin NAT) (EC 3.4.21.62) is one of the most considerable extracellular enzymes produced by Bacillus subtilis natto. The main interest about this enzyme is due to its direct fibrinolytic activity. Being stable enough in the gastrointestinal tract makes this enzyme a useful agent for the oral thrombolytic therapy. Thus, NK is regarded as a valuable dietary supplement or nutraceutical. Proven safety and ease of mass production are other advantages of this enzyme. In addition to these valuable advantages, there are other applications attributed to NK including treatment of hypertension, Alzheimer's disease, and vitreoretinal disorders. This review tends to bring a brief description about this valuable enzyme and summarizes the various biotechnological approaches used in its production, recovery, and purification. Some of the most important applications of NK, as well as its future prospects, are also discussed.

  9. [Developing a harmonised system for the recognition of clinical trials for veterinary product registration].

    PubMed

    Maliandi, F S

    2008-12-01

    The increase of commerce between developing countries requires a harmonised system for accepting the results of clinical trials (CT) of veterinary products, similar to those that exist in developed countries. The objective of this paper is to propose a basis for the creation of a system that harmonises CTs for approving veterinary products (VP) for registration. Such a system would be a step towards unifying the CTs of different countries, while maintaining country-specific variations that are compatible with the scientific method, international standards, and the principles of objectivity, transparency and confidentiality. Basic requirements to be fulfilled by both private institutions and public offices are described, as are professional responsibilities and possible administrative procedures that could be adapted in each country. The conclusion reached is that a harmonised system is feasible, as has been demonstrated in numerous countries throughout the world. A harmonised system will result in a more efficient product approval process, a reduction in costs, greater transparency in controls, an improvement in the reliability of the health system, and a reduction in the time the process takes. It will also contribute to animal welfare by avoiding the need to repeat trials. The author acknowledges that there are cultural, technological and economic limitations and that these problems, and others, have yet to be overcome.

  10. 75 FR 16111 - Antimicrobial Pesticide Products; Registration Applications

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-31

    ...., Midland, MI 48674. Active ingredient: 2,6-Dimethyl-m-dioxan-4-ol acetate Proposed Uses: Material...., 111 RDC Park West Drive, Pittsburgh, PA 15275-1112. Active ingredient: Sodium p-chloro-m-creosolate.... Active ingredient: Potassium peroxymonosulfate; Sodium chlorite. Proposed Uses: Food use in presence of...

  11. 75 FR 30829 - Antimicrobial Pesticide Products; Registration Applications

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-02

    ... (ID) number EPA-HQ- OPP-2010-0325, by one of the following methods: Federal eRulemaking Portal: http... 4 p.m., Monday through Friday, excluding legal holidays). Special arrangements should be made for... your comments to docket ID number EPA-HQ-OPP- 2010-0325. EPA's policy is that all comments...

  12. 75 FR 16109 - Antimicrobial Pesticide Products; Registration Applications

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-31

    .... Company name and address: Schulke & Mayr GMBH Agent (Technology Sciences Group, Inc.), 1150 18 th St., NW... wastewater effluent, disinfection of drinking water, pulp and paperboard water treatment, farm premises...

  13. 40 CFR 152.113 - Approval of registration under FIFRA sec. 3(c)(7)-Products that do not contain a new active...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS PESTICIDE REGISTRATION... registration of a pesticide product, each of whose active ingredients is contained in one or more other... make the determinations required by FIFRA sec. 3(c)(7)(A) or (B) with respect to the pesticide product...

  14. 17 CFR 249.801 - Form X-15AA-1, for application for registration as a national securities association or...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 3 2011-04-01 2011-04-01 false Form X-15AA-1, for application....801 Form X-15AA-1, for application for registration as a national securities association or affiliated...). Editorial Note: For Federal Register citations affecting Form X-15AA-1, see the List of CFR...

  15. 17 CFR 249.801 - Form X-15AA-1, for application for registration as a national securities association or...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 17 Commodity and Securities Exchanges 3 2013-04-01 2013-04-01 false Form X-15AA-1, for application....801 Form X-15AA-1, for application for registration as a national securities association or affiliated...). Editorial Note: For Federal Register citations affecting Form X-15AA-1, see the List of CFR...

  16. 17 CFR 249.801 - Form X-15AA-1, for application for registration as a national securities association or...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 17 Commodity and Securities Exchanges 4 2014-04-01 2014-04-01 false Form X-15AA-1, for application....801 Form X-15AA-1, for application for registration as a national securities association or affiliated...). Editorial Note: For Federal Register citations affecting Form X-15AA-1, see the List of CFR...

  17. 17 CFR 249.801 - Form X-15AA-1, for application for registration as a national securities association or...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 17 Commodity and Securities Exchanges 3 2012-04-01 2012-04-01 false Form X-15AA-1, for application....801 Form X-15AA-1, for application for registration as a national securities association or affiliated...). Editorial Note: For Federal Register citations affecting Form X-15AA-1, see the List of CFR...

  18. 78 FR 16048 - Proposed Collection; Comment Request for e-Services Registration TIN Matching-Application and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-13

    ...--Application and Screens for TIN Matching Interactive AGENCY: Internal Revenue Service (IRS), Treasury. ACTION... screens for TIN matching interactive. DATES: Written comments should be received on or before May 13, 2013... INFORMATION: Title: e-Services Registration TIN Matching--Application and Screens for TIN Matching Interactive...

  19. 75 FR 5854 - Proposed Collection; Comment Request for e-Services Registration TIN Matching-Application and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-04

    ...--Application and Screens for TIN Matching Interactive AGENCY: Internal Revenue Service (IRS), Treasury. ACTION... Screens for TIN Matching Interactive. DATES: Written comments should be received on or before April 5... . SUPPLEMENTARY INFORMATION: Title: e-Services Registration TIN Matching--Application and Screens for TIN Matching...

  20. 17 CFR 240.17g-1 - Application for registration as a nationally recognized statistical rating organization.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... as a nationally recognized statistical rating organization. 240.17g-1 Section 240.17g-1 Commodity and... Statistical Rating Organizations § 240.17g-1 Application for registration as a nationally recognized statistical rating organization. (a) Initial application. A credit rating agency applying to the Commission...

  1. 17 CFR 240.17g-1 - Application for registration as a nationally recognized statistical rating organization.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... as a nationally recognized statistical rating organization. 240.17g-1 Section 240.17g-1 Commodity and... Statistical Rating Organizations § 240.17g-1 Application for registration as a nationally recognized statistical rating organization. (a) Initial application. A credit rating agency applying to the Commission...

  2. 17 CFR 240.17g-1 - Application for registration as a nationally recognized statistical rating organization.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... as a nationally recognized statistical rating organization. 240.17g-1 Section 240.17g-1 Commodity and... Statistical Rating Organizations § 240.17g-1 Application for registration as a nationally recognized statistical rating organization. (a) Initial application. A credit rating agency applying to the Commission...

  3. 17 CFR 240.17g-1 - Application for registration as a nationally recognized statistical rating organization.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... as a nationally recognized statistical rating organization. 240.17g-1 Section 240.17g-1 Commodity and... Statistical Rating Organizations § 240.17g-1 Application for registration as a nationally recognized statistical rating organization. (a) Initial application. A credit rating agency applying to the Commission...

  4. 17 CFR 240.17g-1 - Application for registration as a nationally recognized statistical rating organization.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... as a nationally recognized statistical rating organization. 240.17g-1 Section 240.17g-1 Commodity and... Statistical Rating Organizations § 240.17g-1 Application for registration as a nationally recognized statistical rating organization. (a) Initial application. A credit rating agency applying to the Commission...

  5. 17 CFR 249.1001 - Form SIP, for application for registration as a securities information processor or to amend such...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 17 Commodity and Securities Exchanges 3 2012-04-01 2012-04-01 false Form SIP, for application for... § 249.1001 Form SIP, for application for registration as a securities information processor or to amend... Note: For Federal Register citations affecting Form SIP, see the List of CFR Sections Affected,...

  6. 17 CFR 249.1001 - Form SIP, for application for registration as a securities information processor or to amend such...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 17 Commodity and Securities Exchanges 3 2013-04-01 2013-04-01 false Form SIP, for application for... § 249.1001 Form SIP, for application for registration as a securities information processor or to amend... Note: For Federal Register citations affecting Form SIP, see the List of CFR Sections Affected,...

  7. 17 CFR 249.1001 - Form SIP, for application for registration as a securities information processor or to amend such...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 17 Commodity and Securities Exchanges 4 2014-04-01 2014-04-01 false Form SIP, for application for... § 249.1001 Form SIP, for application for registration as a securities information processor or to amend... Note: For Federal Register citations affecting Form SIP, see the List of CFR Sections Affected,...

  8. 17 CFR 249.1001 - Form SIP, for application for registration as a securities information processor or to amend such...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 3 2011-04-01 2011-04-01 false Form SIP, for application for... § 249.1001 Form SIP, for application for registration as a securities information processor or to amend... Note: For Federal Register citations affecting Form SIP, see the List of CFR Sections Affected,...

  9. 17 CFR 249.1001 - Form SIP, for application for registration as a securities information processor or to amend such...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Form SIP, for application for... § 249.1001 Form SIP, for application for registration as a securities information processor or to amend... Note: For Federal Register citations affecting Form SIP, see the List of CFR Sections Affected,...

  10. 17 CFR 249.801 - Form X-15AA-1, for application for registration as a national securities association or...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Form X-15AA-1, for application....801 Form X-15AA-1, for application for registration as a national securities association or affiliated...). Editorial Note: For Federal Register citations affecting Form X-15AA-1, see the List of CFR Sections...

  11. 78 FR 14847 - Topaz Exchange, LLC; Notice of Filing of Application for Registration as a National Securities...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-07

    ... COMMISSION Topaz Exchange, LLC; Notice of Filing of Application for Registration as a National Securities Exchange Under Section 6 of the Securities Exchange Act of 1934 March 1, 2013. On July 3, 2012, Topaz Exchange, LLC (``Topaz Exchange'' or ``Applicant'') submitted to the Securities and Exchange...

  12. 37 CFR 201.5 - Corrections and amplifications of copyright registrations; applications for supplementary...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... States Code, as amended by Pub. L. 94-553. For the purposes of this section: (i) A basic registration..., or to reflect changes in the content of a work; and (iv) Where a basic renewal registration has been... 17 of the United States Code, as amended by Pub. L. 94-553; (B) A renewal registration made under...

  13. 37 CFR 201.5 - Corrections and amplifications of copyright registrations; applications for supplementary...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ..., or to reflect changes in the content of a work; and (iv) Where a basic renewal registration has been... information given in a registration, under section 408(d) of title 17 of the United States Code, as amended by Pub. L. 94-553. For the purposes of this section: (i) A basic registration means any of the following...

  14. Local tissue-weight-based nonrigid registration of lung images with application to regional ventilation

    NASA Astrophysics Data System (ADS)

    Yin, Youbing; Hoffman, Eric A.; Lin, Ching-Long

    2009-02-01

    In this paper, a new nonrigid image registration method is presented to align two volumetric lung CT datasets with an application to estimate regional ventilation. Instead of the sum of squared intensity difference (SSD), we introduce the sum of squared tissue volume difference (SSTVD) as the similarity criterion to take into account the variation of intensity due to respiration. This new criterion aims to minimize the local difference of tissue volume inside the lungs between two images scanned in the same session or over short periods of time, thus preserving the tissue weight of the lungs. Our approach is tested using a pair of volumetric lung datasets acquired at 15% and 85% of vital capacity (VC) in a single scanning session. The results show that the new SSTVD predicts a smaller registration error and also yields a better alignment of structures within the lungs than the normal SSD similarity measure. In addition, the regional ventilation derived from the new method exhibits a much more improved physiological pattern than that of SSD.

  15. Technical note: deformable image registration on partially matched images for radiotherapy applications.

    PubMed

    Yang, Deshan; Goddu, S Murty; Lu, Wei; Pechenaya, Olga L; Wu, Yu; Deasy, Joseph O; El Naqa, Issam; Low, Daniel A

    2010-01-01

    In radiation therapy applications, deformable image registrations (DIRs) are often carried out between two images that only partially match. Image mismatching could present as superior-inferior coverage differences, field-of-view (FOV) cutoffs, or motion crossing the image boundaries. In this study, the authors propose a method to improve the existing DIR algorithms so that DIR can be carried out in such situations. The basic idea is to extend the image volumes and define the extension voxels (outside the FOV or outside the original image volume) as NaN (not-a-number) values that are transparent to all floating-point computations in the DIR algorithms. Registrations are then carried out with one additional rule that NaN voxels can match any voxels. In this way, the matched sections of the images are registered properly, and the mismatched sections of the images are registered to NaN voxels. This method makes it possible to perform DIR on partially matched images that otherwise are difficult to register. It may also improve DIR accuracy, especially near or in the mismatched image regions.

  16. Technical Note: Deformable image registration on partially matched images for radiotherapy applications

    PubMed Central

    Yang, Deshan; Goddu, S. Murty; Lu, Wei; Pechenaya, Olga L.; Wu, Yu; Deasy, Joseph O.; El Naqa, Issam; Low, Daniel A.

    2010-01-01

    In radiation therapy applications, deformable image registrations (DIRs) are often carried out between two images that only partially match. Image mismatching could present as superior-inferior coverage differences, field-of-view (FOV) cutoffs, or motion crossing the image boundaries. In this study, the authors propose a method to improve the existing DIR algorithms so that DIR can be carried out in such situations. The basic idea is to extend the image volumes and define the extension voxels (outside the FOV or outside the original image volume) as NaN (not-a-number) values that are transparent to all floating-point computations in the DIR algorithms. Registrations are then carried out with one additional rule that NaN voxels can match any voxels. In this way, the matched sections of the images are registered properly, and the mismatched sections of the images are registered to NaN voxels. This method makes it possible to perform DIR on partially matched images that otherwise are difficult to register. It may also improve DIR accuracy, especially near or in the mismatched image regions. PMID:20175475

  17. Simultaneous fine and coarse diffeomorphic registration: application to atrophy measurement in Alzheimer's disease.

    PubMed

    Risser, Laurent; Vialard, François-Xavier; Wolz, Robin; Holm, Darryl D; Rueckert, Daniel

    2010-01-01

    In this paper, we present a fine and coarse approach for the multiscale registration of 3D medical images using Large Deformation Diffeomorphic Metric Mapping (LDDMM). This approach has particularly interesting properties since it estimates large, smooth and invertible optimal deformations having a rich descriptive power for the quantification of temporal changes in the images. First, we show the importance of the smoothing kernel and its influence on the final solution. We then propose a new strategy for the spatial regularization of the deformations, which uses simultaneously fine and coarse smoothing kernels. We have evaluated the approach on both 2D synthetic images as well as on 3D MR longitudinal images out of the Alzheimer's Disease Neuroimaging Initiative (ADNI) study. Results highlight the regularizing properties of our approach for the registration of complex shapes. More importantly, the results also demonstrate its ability to measure shape variations at several scales simultaneously while keeping the desirable properties of LDDMM. This opens new perspectives for clinical applications.

  18. [Preliminary application of an improved Demons deformable registration algorithm in tumor radiotherapy].

    PubMed

    Zhou, Lu; Zhen, Xin; Lu, Wenting; Dou, Jianhong; Zhou, Linghong

    2012-01-01

    To validate the efficiency of an improved Demons deformable registration algorithm and evaluate its application in registration of the treatment image and the planning image in image-guided radiotherapy (IGRT). Based on Brox's gradient constancy assumption and Malis's efficient second-order minimization algorithm, a grey value gradient similarity term was added into the original energy function, and a formula was derived to calculate the update of transformation field. The limited Broyden-Fletcher-Goldfarb-Shanno (L-BFGS) algorithm was used to optimize the energy function for automatic determination of the iteration number. The proposed algorithm was validated using mathematically deformed images, physically deformed phantom images and clinical tumor images. Compared with the original Additive Demons algorithm, the improved Demons algorithm achieved a higher precision and a faster convergence speed. Due to the influence of different scanning conditions in fractionated radiation, the density range of the treatment image and the planning image may be different. The improved Demons algorithm can achieve faster and more accurate radiotherapy.

  19. Installed Base Registration of Decentralised Solar Panels with Applications in Crisis Management

    NASA Astrophysics Data System (ADS)

    Aarsen, R.; Janssen, M.; Ramkisoen, M.; Biljecki, F.; Quak, W.; Verbree, E.

    2015-08-01

    In case of a calamity in the Netherlands - e.g. a dike breach - parts of the nationwide electric network can fall out. In these occasions it would be useful if decentralised energy sources of the Smart Grid would contribute to balance out the fluctuations of the energy network. Decentralised energy sources include: solar energy, wind energy, combined heat and power, and biogas. In this manner, parts of the built environment - e.g. hospitals - that are in need of a continuous power flow, could be secured of this power. When a calamity happens, information about the Smart Grid is necessary to control the crisis and to ensure a shared view on the energy networks for both the crisis managers and network operators. The current situation of publishing, storing and sharing data of solar energy has been shown a lack of reliability about the current number, physical location, and capacity of installed decentralised photovoltaic (PV) panels in the Netherlands. This study focuses on decentralised solar energy in the form of electricity via PV panels in the Netherlands and addresses this challenge by proposing a new, reliable and up-to-date database. The study reveals the requirements for a registration of the installed base of PV panels in the Netherlands. This new database should serve as a replenishment for the current national voluntary registration, called Production Installation Register of Energy Data Services Netherland (EDSN-PIR), of installed decentralised PV panel installations in the Smart Grid, and provide important information in case of a calamity.

  20. Multiscale registration of medical images based on edge preserving scale space with application in image-guided radiation therapy

    NASA Astrophysics Data System (ADS)

    Li, Dengwang; Li, Hongsheng; Wan, Honglin; Chen, Jinhu; Gong, Guanzhong; Wang, Hongjun; Wang, Liming; Yin, Yong

    2012-08-01

    Mutual information (MI) is a well-accepted similarity measure for image registration in medical systems. However, MI-based registration faces the challenges of high computational complexity and a high likelihood of being trapped into local optima due to an absence of spatial information. In order to solve these problems, multi-scale frameworks can be used to accelerate registration and improve robustness. Traditional Gaussian pyramid representation is one such technique but it suffers from contour diffusion at coarse levels which may lead to unsatisfactory registration results. In this work, a new multi-scale registration framework called edge preserving multiscale registration (EPMR) was proposed based upon an edge preserving total variation L1 norm (TV-L1) scale space representation. TV-L1 scale space is constructed by selecting edges and contours of images according to their size rather than the intensity values of the image features. This ensures more meaningful spatial information with an EPMR framework for MI-based registration. Furthermore, we design an optimal estimation of the TV-L1 parameter in the EPMR framework by training and minimizing the transformation offset between the registered pairs for automated registration in medical systems. We validated our EPMR method on both simulated mono- and multi-modal medical datasets with ground truth and clinical studies from a combined positron emission tomography/computed tomography (PET/CT) scanner. We compared our registration framework with other traditional registration approaches. Our experimental results demonstrated that our method outperformed other methods in terms of the accuracy and robustness for medical images. EPMR can always achieve a small offset value, which is closer to the ground truth both for mono-modality and multi-modality, and the speed can be increased 5-8% for mono-modality and 10-14% for multi-modality registration under the same condition. Furthermore, clinical application by adaptive

  1. Multiscale properties of weighted total variation flow with applications to denoising and registration.

    PubMed

    Athavale, Prashant; Xu, Robert; Radau, Perry; Nachman, Adrian; Wright, Graham A

    2015-07-01

    Images consist of structures of varying scales: large scale structures such as flat regions, and small scale structures such as noise, textures, and rapidly oscillatory patterns. In the hierarchical (BV, L(2)) image decomposition, Tadmor, et al. (2004) start with extracting coarse scale structures from a given image, and successively extract finer structures from the residuals in each step of the iterative decomposition. We propose to begin instead by extracting the finest structures from the given image and then proceed to extract increasingly coarser structures. In most images, noise could be considered as a fine scale structure. Thus, starting the image decomposition with finer scales, rather than large scales, leads to fast denoising. We note that our approach turns out to be equivalent to the nonstationary regularization in Scherzer and Weickert (2000). The continuous limit of this procedure leads to a time-scaled version of total variation flow. Motivated by specific clinical applications, we introduce an image depending weight in the regularization functional, and study the corresponding weighted TV flow. We show that the edge-preserving property of the multiscale representation of an input image obtained with the weighted TV flow can be enhanced and localized by appropriate choice of the weight. We use this in developing an efficient and edge-preserving denoising algorithm with control on speed and localization properties. We examine analytical properties of the weighted TV flow that give precise information about the denoising speed and the rate of change of energy of the images. An additional contribution of the paper is to use the images obtained at different scales for robust multiscale registration. We show that the inherently multiscale nature of the weighted TV flow improved performance for registration of noisy cardiac MRI images, compared to other methods such as bilateral or Gaussian filtering. A clinical application of the multiscale registration

  2. Suspension of Registrations under FIFRA

    EPA Pesticide Factsheets

    Under FIFRA Section 3(c)(2)(B), this generally halts further distribution and sale of the suspended pesticide product by the registrant. Find suspension listings by product name, active ingredient, registrant name, date, and contact information.

  3. Pesticide Registration Manual: Chapter 10 - Data Compensation Requirements

    EPA Pesticide Factsheets

    This chapter provides information about data compensation requirements, procedures, and obligations when submitting an application for registration, amended registration, reregistration or registration review.

  4. Contacts in the Office of Pesticide Programs, Registration Division

    EPA Pesticide Factsheets

    The Registration Division (RD) is responsible product registrations, amendments, registrations, tolerances, experimental use permits, and emergency exemptions for conventional chemical pesticides. Find contacts in this division.

  5. The use of community herbal monographs to facilitate registrations and authorisations of herbal medicinal products in the European Union 2004-2012.

    PubMed

    Peschel, Wieland

    2014-12-02

    The provisions for the simplified registration of traditional herbal medicinal products in the European Union were introduced by Directive 2004/24/EC amending Directive 2001/83/EC (Chapter 2a) in 2004. Since implementation in the European member states until December 2012 a total of 1015 registrations (traditional use) and 514 authorisations (well-established use) have been granted for products containing substances/ preparations from about 200 different herbal drugs. The overall number of received applications with more than one third still under assessment suggests a further increase for the next years. This review summarises the main features of registered and authorised herbal medicinal products in the EU and evaluates available data against provisions of Directive 2004/24/EC and European standards established by the Committee on Herbal Medicinal Products at the European Medicines Agency. The supportive function of Community herbal monographs is described as regards availability and their use in national procedures, which is complemented by an analysis of specific future challenges from experiences made with the implementation of Directive 2004/24/EC so far.

  6. 75 FR 51295 - In the Matter of the Application of BATS Y-Exchange, Inc. for Registration as a National...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-19

    ... COMMISSION In the Matter of the Application of BATS Y-Exchange, Inc. for Registration as a National... October 20, 2009, BATS Y-Exchange, Inc. (``BATS Y Exchange'' or ``Exchange'') submitted to the Securities... January 28, 2010.\\2\\ The Commission received no comments regarding the BATS Y Exchange Form 1. On July...

  7. 75 FR 4595 - BATS Y-Exchange, Inc.; Notice of Filing of Application for Registration as a National Securities...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-28

    ... COMMISSION BATS Y-Exchange, Inc.; Notice of Filing of Application for Registration as a National Securities... Y-Exchange, Inc. (``BATS Y Exchange'') submitted to the Securities and Exchange Commission... publishing this notice to solicit comments on BATS Y Exchange's Form 1. The Commission will take...

  8. Electronic Submissions of Pesticide Applications

    EPA Pesticide Factsheets

    Applications for pesticide registration can be submitted electronically, including forms, studies, and draft product labeling. Applicants need not submit multiple electronic copies of any pieces of their applications.

  9. 14 CFR 297.22 - Procedure on receipt of registration application.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... (AVIATION PROCEEDINGS) ECONOMIC REGULATIONS FOREIGN AIR FREIGHT FORWARDERS AND FOREIGN COOPERATIVE SHIPPERS ASSOCIATIONS Registration for Foreign Air Freight Forwarders and Foreign Cooperative Shippers Associations...

  10. Patient-specific model of brain deformation: application to medical image registration.

    PubMed

    Wittek, Adam; Miller, Karol; Kikinis, Ron; Warfield, Simon K

    2007-01-01

    This contribution presents finite element computation of the deformation field within the brain during craniotomy-induced brain shift. The results were used to illustrate the capabilities of non-linear (i.e. accounting for both geometric and material non-linearities) finite element analysis in non-rigid registration of pre- and intra-operative magnetic resonance images of the brain. We used patient-specific hexahedron-dominant finite element mesh, together with realistic material properties for the brain tissue and appropriate contact conditions at boundaries. The model was loaded by the enforced motion of nodes (i.e. through prescribed motion of a boundary) at the brain surface in the craniotomy area. We suggest using explicit time-integration scheme for discretised equations of motion, as the computational times are much shorter and accuracy, for practical purposes, the same as in the case of implicit integration schemes. Application of the computed deformation field to register (i.e. align) the pre-operative images with the intra-operative ones indicated that the model very accurately predicts the displacements of the tumour and the lateral ventricles even for limited information about the brain surface deformation. The prediction accuracy improves when information about deformation of not only exposed (during craniotomy) but also unexposed parts of the brain surface is used when prescribing loading. However, it appears that the accuracy achieved using information only about the deformation of the exposed surface, that can be determined without intra-operative imaging, is acceptable. The presented results show that non-linear biomechanical models can complement medical image processing techniques when conducting non-rigid registration. Important advantage of such models over the previously used linear ones is that they do not require unrealistic assumptions that brain deformations are infinitesimally small and brain stress-strain relationship is linear.

  11. CT and MR image fusion of tandem and ring applicator using rigid registration in intracavitary brachytherapy planning.

    PubMed

    Oinam, Arun S; Tomar, Parsee; Patel, Firuza D; Singh, Lakhwant; Rai, Bhavana; Bahl, Amit

    2014-03-06

    The purpose of this study is to find the uncertainties in the reconstruction of MR compatible ring-tandem intracavitary applicators of high-dose rate image-based brachytherapy treatment planning using rigid registration of 3D MR and CT image fusion. Tandem and ring reconstruction in MR image based brachytherapy planning was done using rigid registration of CT and MR applicator geometries. Verifications of registration for applicator fusion were performed in six verification steps at three different sites of tandem ring applicator set. The first site consists of three errors at the level of ring plane in (1) cranio caudal shift (Cranial Shift) of ring plane along tandem axis, (2) antero-posterior shift (AP Shift) perpendicular to tandem axis on the plane containing the tandem, and (3) lateral shift (Lat Shift) perpendicular to the plane containing the tandem at the level of ring plane. The other two sites are the verifications at the tip of tandem and neck of the ring. The verification at the tip of tandem consists of two errors in (1) antero-posterior shift (AP Shift) perpendicular to tandem axis on the plane containing the tandem, and (2) lateral shift (Lat Shift) perpendicular to the plane containing the tandem. The third site of verification at the neck of the ring is the error due to the rotation of ring about tandem axis. The impact of translational errors from -5 mm to 5 mm in the step of 1 mm along x-, y-, and z-axis and three rotational errors about these axes from -19.1° to 19.1° in the step of 3.28° on dose-volume histogram parameters (D(2cc), D(1cc), D(0.1cc), and D(5cc) of bladder, rectum, and sigmoid, and D90 and D98 of HRCTV were also analyzed. Maximum registration errors along cranio-caudal direction was 2.2 mm (1 case), whereas the errors of 31 out of 34 cases of registration were found within 1.5 mm, and those of two cases were less than 2mm but greater than 1.5 mm. Maximum rotational error of ring about tandem axis was 3.15° (1.1 mm). In other

  12. Image Registration Workshop Proceedings

    NASA Technical Reports Server (NTRS)

    LeMoigne, Jacqueline (Editor)

    1997-01-01

    Automatic image registration has often been considered as a preliminary step for higher-level processing, such as object recognition or data fusion. But with the unprecedented amounts of data which are being and will continue to be generated by newly developed sensors, the very topic of automatic image registration has become and important research topic. This workshop presents a collection of very high quality work which has been grouped in four main areas: (1) theoretical aspects of image registration; (2) applications to satellite imagery; (3) applications to medical imagery; and (4) image registration for computer vision research.

  13. An Automatic Registration-Fusion Scheme Based on Similarity Measures: An Application to Dental Imaging

    DTIC Science & Technology

    2007-11-02

    calculation of similarity measures between two dental radiographic images to be registered. Moreover, a fusion process has been developed to combine...information from registered dental images. Result on clinical data reveals the advantageous performance of the proposed automatic registration method...registration approach outperforms despite the fuzzy dental boundaries and the lack of characteristic edges of the radiographic images. These preliminary

  14. 17 CFR 275.203-1 - Application for investment adviser registration.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... registration after January 1, 2011, you must file a brochure(s) that satisfies the requirements of Part 2A of...)) on July 20, 2011, you are exempt from registration with the Commission as an investment adviser until...: For Federal Register citations affecting Form ADV, see the List of CFR Sections Affected, which...

  15. 40 CFR 79.10 - Application for registration by fuel manufacturer.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... manufacturer. 79.10 Section 79.10 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) REGISTRATION OF FUELS AND FUEL ADDITIVES Fuel Registration Procedures § 79.10... in § 79.11. If the manufacturer produces more than one grade or brand of a designated fuel, a...

  16. 40 CFR 79.10 - Application for registration by fuel manufacturer.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... manufacturer. 79.10 Section 79.10 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) REGISTRATION OF FUELS AND FUEL ADDITIVES Fuel Registration Procedures § 79.10... in § 79.11. If the manufacturer produces more than one grade or brand of a designated fuel, a...

  17. 77 FR 9522 - Requirements for Consumer Registration of Durable Infant or Toddler Products

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-17

    ...): A third comment suggested that we allow Quick Response (``QR'') codes on registration cards. The comment explained that QR codes ``are a type of matrix barcode that allow storage of information... phone or other device.'' (Response 3): We agree that QR codes and other barcode technologies that...

  18. Stopping Criteria for Log-Domain Diffeomorphic Demons Registration: An Experimental Survey for Radiotherapy Application.

    PubMed

    Peroni, M; Golland, P; Sharp, G C; Baroni, G

    2016-02-01

    A crucial issue in deformable image registration is achieving a robust registration algorithm at a reasonable computational cost. Given the iterative nature of the optimization procedure an algorithm must automatically detect convergence, and stop the iterative process when most appropriate. This paper ranks the performances of three stopping criteria and six stopping value computation strategies for a Log-Domain Demons Deformable registration method simulating both a coarse and a fine registration. The analyzed stopping criteria are: (a) velocity field update magnitude, (b) mean squared error, and (c) harmonic energy. Each stoping condition is formulated so that the user defines a threshold ∊, which quantifies the residual error that is acceptable for the particular problem and calculation strategy. In this work, we did not aim at assigning a value to e, but to give insights in how to evaluate and to set the threshold on a given exit strategy in a very popular registration scheme. Experiments on phantom and patient data demonstrate that comparing the optimization metric minimum over the most recent three iterations with the minimum over the fourth to sixth most recent iterations can be an appropriate algorithm stopping strategy. The harmonic energy was found to provide best trade-off between robustness and speed of convergence for the analyzed registration method at coarse registration, but was outperformed by mean squared error when all the original pixel information is used. This suggests the need of developing mathematically sound new convergence criteria in which both image and vector field information could be used to detect the actual convergence, which could be especially useful when considering multi-resolution registrations. Further work should be also dedicated to study same strategies performances in other deformable registration methods and body districts. © The Author(s) 2014.

  19. Stopping Criteria for Log-Domain Diffeomorphic Demons Registration: An Experimental Survey for Radiotherapy Application

    PubMed Central

    Peroni, M.; Golland, P.; Sharp, G. C.; Baroni, G.

    2016-01-01

    A crucial issue in deformable image registration is achieving a robust registration algorithm at a reasonable computational cost. Given the iterative nature of the optimization procedure an algorithm must automatically detect convergence, and stop the iterative process when most appropriate. This paper ranks the performances of three stopping criteria and six stopping value computation strategies for a Log-Domain Demons Deformable registration method simulating both a coarse and a fine registration. The analyzed stopping criteria are: (a) velocity field update magnitude, (b) mean squared error, and (c) harmonic energy. Each stopping condition is formulated so that the user defines a threshold ε, which quantifies the residual error that is acceptable for the particular problem and calculation strategy. In this work, we did not aim at assigning a value to ε, but to give insights in how to evaluate and to set the threshold on a given exit strategy in a very popular registration scheme. Experiments on phantom and patient data demonstrate that comparing the optimization metric minimum over the most recent three iterations with the minimum over the fourth to sixth most recent iterations can be an appropriate algorithm stopping strategy. The harmonic energy was found to provide best trade-off between robustness and speed of convergence for the analyzed registration method at coarse registration, but was outperformed by mean squared error when all the original pixel information is used. This suggests the need of developing mathematically sound new convergence criteria in which both image and vector field information could be used to detect the actual convergence, which could be especially useful when considering multi-resolution registrations. Further work should be also dedicated to study same strategies performances in other deformable registration methods and body districts. PMID:24000996

  20. Invariant Feature Matching for Image Registration Application Based on New Dissimilarity of Spatial Features

    PubMed Central

    Mousavi Kahaki, Seyed Mostafa; Nordin, Md Jan; Ashtari, Amir H.; J. Zahra, Sophia

    2016-01-01

    An invariant feature matching method is proposed as a spatially invariant feature matching approach. Deformation effects, such as affine and homography, change the local information within the image and can result in ambiguous local information pertaining to image points. New method based on dissimilarity values, which measures the dissimilarity of the features through the path based on Eigenvector properties, is proposed. Evidence shows that existing matching techniques using similarity metrics—such as normalized cross-correlation, squared sum of intensity differences and correlation coefficient—are insufficient for achieving adequate results under different image deformations. Thus, new descriptor’s similarity metrics based on normalized Eigenvector correlation and signal directional differences, which are robust under local variation of the image information, are proposed to establish an efficient feature matching technique. The method proposed in this study measures the dissimilarity in the signal frequency along the path between two features. Moreover, these dissimilarity values are accumulated in a 2D dissimilarity space, allowing accurate corresponding features to be extracted based on the cumulative space using a voting strategy. This method can be used in image registration applications, as it overcomes the limitations of the existing approaches. The output results demonstrate that the proposed technique outperforms the other methods when evaluated using a standard dataset, in terms of precision-recall and corner correspondence. PMID:26985996

  1. Real-time geometric registration using feature landmark database for augmented reality applications

    NASA Astrophysics Data System (ADS)

    Taketomi, Takafumi; Sato, Tomokazu; Yokoya, Naokazu

    2009-02-01

    In the field of augmented reality, it is important to solve a geometric registration problem between real and virtual worlds. To solve this problem, many kinds of image based online camera parameter estimation methods have been proposed. As one of these methods, we have been proposed a feature landmark based camera parameter estimation method. In this method, extrinsic camera parameters are estimated from corresponding landmarks and image features. Although the method can work in large and complex environments, our previous method cannot work in real-time due to high computational cost in matching process. Additionally, initial camera parameters for the first frame must be given manually. In this study, we realize real-time and manual-initialization free camera parameter estimation based on feature landmark database. To reduce the computational cost of the matching process, the number of matching candidates is reduced by using priorities of landmarks that are determined from previously captured video sequences. Initial camera parameter for the first frame is determined by a voting scheme for the target space using matching candidates. To demonstrate the effectiveness of the proposed method, applications of landmark based real-time camera parameter estimation are demonstrated in outdoor environments.

  2. Automatic segmentation of medical images using image registration: diagnostic and simulation applications.

    PubMed

    Barber, D C; Hose, D R

    2005-01-01

    Automatic identification of the boundaries of significant structure (segmentation) within a medical image is an are of ongoing research. Various approaches have been proposed but only two methods have achieved widespread use: manual delineation of boundaries and segmentation using intensity values. In this paper we describe an approach based on image registration. A reference image is prepared and segmented, by hand or otherwise. A patient image is registered to the reference image and the mapping then applied to ther reference segmentation to map it back to the patient image. In general a high-resolution nonlinear mapping is required to achieve accurate segmentation. This paper describes an algorithm that can efficiently generate such mappings, and outlines the uses of this tool in two relevant applications. An important feature of the approach described in this paper is that the algorithm is independent of the segmentation problem being addresses. All knowledge about the problem at hand is contained in files of reference data. A secondary benefit is that the continuous three-dimensional mapping generated is well suited to the generation of patient-specific numerical models (e.g. finite element meshes) from the library models. Smoothness constraints in the morphing algorithm tend to maintain the geometric quality of the reference mesh.

  3. The need for application-based adaptation of deformable image registration

    SciTech Connect

    Kirby, Neil; Chuang, Cynthia; Ueda, Utako; Pouliot, Jean

    2013-01-15

    Purpose: To utilize a deformable phantom to objectively evaluate the accuracy of 11 different deformable image registration (DIR) algorithms. Methods: The phantom represents an axial plane of the pelvic anatomy. Urethane plastic serves as the bony anatomy and urethane rubber with three levels of Hounsfield units (HU) is used to represent fat and organs, including the prostate. A plastic insert is placed into the phantom to simulate bladder filling. Nonradiopaque markers reside on the phantom surface. Optical camera images of these markers are used to measure the positions and determine the deformation from the bladder insert. Eleven different DIR algorithms are applied to the full and empty-bladder computed tomography images of the phantom (fixed and moving volumes, respectively) to calculate the deformation. The algorithms include those from MIM Software (MIM) and Velocity Medical Solutions (VEL) and nine different implementations from the deformable image registration and adaptive radiotherapy toolbox for Matlab. These algorithms warp one image to make it similar to another, but must utilize a method for regularization to avoid physically unrealistic deformation scenarios. The mean absolute difference (MAD) between the HUs at the marker locations on one image and the calculated location on the other serves as a metric to evaluate the balance between image similarity and regularization. To demonstrate the effect of regularization on registration accuracy, an additional beta version of MIM was created with a variable smoothness factor that controls the emphasis of the algorithm on regularization. The distance to agreement between the measured and calculated marker deformations is used to compare the overall spatial accuracy of the DIR algorithms. This overall spatial accuracy is also utilized to evaluate the phantom geometry and the ability of the phantom soft-tissue heterogeneity to represent patient data. To evaluate the ability of the DIR algorithms to

  4. [Application of elastic registration based on Demons algorithm in cone beam CT].

    PubMed

    Pang, Haowen; Sun, Xiaoyang

    2014-02-01

    We applied Demons and accelerated Demons elastic registration algorithm in radiotherapy cone beam CT (CBCT) images, We provided software support for real-time understanding of organ changes during radiotherapy. We wrote a 3D CBCT image elastic registration program using Matlab software, and we tested and verified the images of two patients with cervical cancer 3D CBCT images for elastic registration, based on the classic Demons algorithm, minimum mean square error (MSE) decreased 59.7%, correlation coefficient (CC) increased 11.0%. While for the accelerated Demons algorithm, MSE decreased 40.1%, CC increased 7.2%. The experimental verification with two methods of Demons algorithm obtained the desired results, but the small difference appeared to be lack of precision, and the total registration time was a little long. All these problems need to be further improved for accuracy and reducing of time.

  5. The Johns Hopkins Address Registration System (JHARS): Anatomy of an Application.

    ERIC Educational Resources Information Center

    Cyzyk, Mark

    2003-01-01

    Describes the registration system at Johns Hopkins University, Maryland, which allows centralized administration and self-signup for access to the Hopkins network. Reception of the system has been overwhelmingly positive. (SLD)

  6. [Validation of an improved Demons deformable registration algorithm and its application in re-contouring in 4D-CT].

    PubMed

    Zhen, Xin; Zhou, Ling-hong; Lu, Wen-ting; Zhang, Shu-xu; Zhou, Lu

    2010-12-01

    To validate the efficiency and accuracy of an improved Demons deformable registration algorithm and evaluate its application in contour recontouring in 4D-CT. To increase the additional Demons force and reallocate the bilateral forces to accelerate convergent speed, we propose a novel energy function as the similarity measure, and utilize a BFGS method for optimization to avoid specifying the numbers of iteration. Mathematical transformed deformable CT images and home-made deformable phantom were used to validate the accuracy of the improved algorithm, and its effectiveness for contour recontouring was tested. The improved algorithm showed a relatively high registration accuracy and speed when compared with the classic Demons algorithm and optical flow based method. Visual inspection of the positions and shapes of the deformed contours agreed well with the physician-drawn contours. Deformable registration is a key technique in 4D-CT, and this improved Demons algorithm for contour recontouring can significantly reduce the workload of the physicians. The registration accuracy of this method proves to be sufficient for clinical needs.

  7. An efficient strategy based on an individualized selection of registration methods. Application to the coregistration of MR and SPECT images in neuro-oncology.

    PubMed

    Tacchella, Jean-Marc; Roullot, Elodie; Lefort, Muriel; Cohen, Mike-Ely; Guillevin, Rémy; Petrirena, Grégorio; Delattre, Jean-Yves; Habert, Marie-Odile; Yeni, Nathanaëlle; Kas, Aurélie; Frouin, Frédérique

    2014-11-21

    An efficient registration strategy is described that aims to help solve delicate medical imaging registration problems. It consists of running several registration methods for each dataset and selecting the best one for each specific dataset, according to an evaluation criterion. Finally, the quality of the registration results, obtained with the best method, is visually scored by an expert as excellent, correct or poor. The strategy was applied to coregister Technetium-99m Sestamibi SPECT and MRI data in the framework of a follow-up protocol in patients with high grade gliomas receiving antiangiogenic therapy. To adapt the strategy to this clinical context, a robust semi-automatic evaluation criterion based on the physiological uptake of the Sestamibi tracer was defined. A panel of eighteen multimodal registration algorithms issued from BrainVisa, SPM or AIR software environments was systematically applied to the clinical database composed of sixty-two datasets. According to the expert visual validation, this new strategy provides 85% excellent registrations, 12% correct ones and only 3% poor ones. These results compare favorably to the ones obtained by the globally most efficient registration method over the whole database, for which only 61% of excellent registration results have been reported. Thus the registration strategy in its current implementation proves to be suitable for clinical application.

  8. An efficient strategy based on an individualized selection of registration methods. Application to the coregistration of MR and SPECT images in neuro-oncology

    NASA Astrophysics Data System (ADS)

    Tacchella, Jean-Marc; Roullot, Elodie; Lefort, Muriel; Cohen, Mike-Ely; Guillevin, Rémy; Petrirena, Grégorio; Delattre, Jean-Yves; Habert, Marie-Odile; Yeni, Nathanaëlle; Kas, Aurélie; Frouin, Frédérique

    2014-11-01

    An efficient registration strategy is described that aims to help solve delicate medical imaging registration problems. It consists of running several registration methods for each dataset and selecting the best one for each specific dataset, according to an evaluation criterion. Finally, the quality of the registration results, obtained with the best method, is visually scored by an expert as excellent, correct or poor. The strategy was applied to coregister Technetium-99m Sestamibi SPECT and MRI data in the framework of a follow-up protocol in patients with high grade gliomas receiving antiangiogenic therapy. To adapt the strategy to this clinical context, a robust semi-automatic evaluation criterion based on the physiological uptake of the Sestamibi tracer was defined. A panel of eighteen multimodal registration algorithms issued from BrainVisa, SPM or AIR software environments was systematically applied to the clinical database composed of sixty-two datasets. According to the expert visual validation, this new strategy provides 85% excellent registrations, 12% correct ones and only 3% poor ones. These results compare favorably to the ones obtained by the globally most efficient registration method over the whole database, for which only 61% of excellent registration results have been reported. Thus the registration strategy in its current implementation proves to be suitable for clinical application.

  9. Application of manufactured products

    NASA Technical Reports Server (NTRS)

    Sastri, Sankar; Duke, Michael B.

    1992-01-01

    A wide range of products can be manufactured from the following materials: (1) lunar regolith or basalt; (2) regolith or rock beneficiated to concentrate plagioclase or other minerals; (3) iron, extracted from lunar soil or rocks by various means; (4) naturally occurring or easily obtained materials that have cementitious properties; and (5) byproducts of the above materials. Among the products that can be produced from these materials are the following: beams; plates and sheets; transparent plates (windows); bricks and blocks; pipes and tubes; low-density materials (foams); fiber, wire, and cables; foils and reflective coatings; hermetic seals (coatings); and formed objects. In addition to oxygen, which can be obtained by several processes, either from unbeneficiated regolith or by reduction of concentrated ilmenite, these materials make the simplest requirements of the lunar resource extraction system. A thorough analysis of the impact of these simplest products on the economics of space operations is not possible at this point. Research is necessary both to define optimum techniques and adapt them to space and to determine the probable market for the products so that the priority of various processes can be assessed. Discussions of the following products are presented: aerobraking heat shields; pressurized habitats; lunar photovoltaic farms; and agricultural systems.

  10. Tensor-based morphometry with stationary velocity field diffeomorphic registration: Application to ADNI

    PubMed Central

    Bossa, Matias; Zacur, Ernesto; Olmos, Salvador

    2010-01-01

    Tensor-based morphometry (TBM) is an analysis technique where anatomical information is characterized by means of the spatial transformations mapping a customized template with the observed images. Therefore, accurate inter-subject non-rigid registration is an essential prerequisite for both template estimation and image warping. Subsequent statistical analysis on the spatial transformations is performed to highlight voxel-wise differences. Most of previous TBM studies did not explore the influence of the registration parameters, such as the parameters defining the deformation and the regularization models. In this work performance evaluation of TBM using stationary velocity field (SVF) diffeomorphic registration was performed in a subset of subjects from Alzheimer’s Disease Neuroimaging Initiative (ADNI) study. A wide range of values of the registration parameters that define the transformation smoothness and the balance between image matching and regularization were explored in the evaluation. The proposed methodology provided brain atrophy maps with very detailed anatomical resolution and with a high significance level compared with results recently published on the same data set using a non-linear elastic registration method. PMID:20211269

  11. 40 CFR 152.113 - Approval of registration under FIFRA sec. 3(c)(7)-Products that do not contain a new active...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... sec. 3(c)(7)-Products that do not contain a new active ingredient. 152.113 Section 152.113 Protection... FIFRA sec. 3(c)(7)—Products that do not contain a new active ingredient. (a) Except as provided in... registration of a pesticide product, each of whose active ingredients is contained in one or more...

  12. 40 CFR 152.113 - Approval of registration under FIFRA sec. 3(c)(7)-Products that do not contain a new active...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... sec. 3(c)(7)-Products that do not contain a new active ingredient. 152.113 Section 152.113 Protection... FIFRA sec. 3(c)(7)—Products that do not contain a new active ingredient. (a) Except as provided in... registration of a pesticide product, each of whose active ingredients is contained in one or more...

  13. 40 CFR 152.113 - Approval of registration under FIFRA sec. 3(c)(7)-Products that do not contain a new active...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... sec. 3(c)(7)-Products that do not contain a new active ingredient. 152.113 Section 152.113 Protection... FIFRA sec. 3(c)(7)—Products that do not contain a new active ingredient. (a) Except as provided in... registration of a pesticide product, each of whose active ingredients is contained in one or more...

  14. 27 CFR 17.21 - Registration.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2014-04-01 2014-04-01 false Registration. 17.21... PRODUCTS Registration § 17.21 Registration. Every person claiming drawback under this part must register annually as a nonbeverage domestic drawback claimant. Registration will be accomplished when the...

  15. 9 CFR 381.179 - Registration.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 9 Animals and Animal Products 2 2014-01-01 2014-01-01 false Registration. 381.179 Section 381.179... CERTIFICATION POULTRY PRODUCTS INSPECTION REGULATIONS Records, Registration, and Reports § 381.179 Registration... effective date. All information submitted shall be current and correct. The registration form shall...

  16. 27 CFR 17.21 - Registration.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Registration. 17.21... PRODUCTS Registration § 17.21 Registration. Every person claiming drawback under this part must register annually as a nonbeverage domestic drawback claimant. Registration will be accomplished when the...

  17. 9 CFR 381.179 - Registration.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 9 Animals and Animal Products 2 2011-01-01 2011-01-01 false Registration. 381.179 Section 381.179... CERTIFICATION POULTRY PRODUCTS INSPECTION REGULATIONS Records, Registration, and Reports § 381.179 Registration... effective date. All information submitted shall be current and correct. The registration form shall...

  18. 9 CFR 381.179 - Registration.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 9 Animals and Animal Products 2 2013-01-01 2013-01-01 false Registration. 381.179 Section 381.179... CERTIFICATION POULTRY PRODUCTS INSPECTION REGULATIONS Records, Registration, and Reports § 381.179 Registration... effective date. All information submitted shall be current and correct. The registration form shall...

  19. 27 CFR 17.21 - Registration.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2012-04-01 2012-04-01 false Registration. 17.21... PRODUCTS Registration § 17.21 Registration. Every person claiming drawback under this part must register annually as a nonbeverage domestic drawback claimant. Registration will be accomplished when the...

  20. 27 CFR 17.21 - Registration.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2011-04-01 2011-04-01 false Registration. 17.21... PRODUCTS Registration § 17.21 Registration. Every person claiming drawback under this part must register annually as a nonbeverage domestic drawback claimant. Registration will be accomplished when the...

  1. 9 CFR 381.179 - Registration.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 9 Animals and Animal Products 2 2012-01-01 2012-01-01 false Registration. 381.179 Section 381.179... CERTIFICATION POULTRY PRODUCTS INSPECTION REGULATIONS Records, Registration, and Reports § 381.179 Registration... effective date. All information submitted shall be current and correct. The registration form shall...

  2. 27 CFR 17.21 - Registration.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2013-04-01 2013-04-01 false Registration. 17.21... PRODUCTS Registration § 17.21 Registration. Every person claiming drawback under this part must register annually as a nonbeverage domestic drawback claimant. Registration will be accomplished when the...

  3. 21 CFR 1309.42 - Certificate of registration; denial of registration.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...; denial of registration. (a) The Administrator shall issue a Certificate of Registration (DEA Form 511) to..., shall hold a hearing on the application pursuant to § 1309.51. (b) The Certificate of Registration...

  4. 21 CFR 1301.35 - Certificate of registration; denial of registration.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... registration. (a) The Administrator shall issue a Certificate of Registration (DEA Form 223) to an applicant if... Federal Register. (c) The Certificate of Registration (DEA Form 223) shall contain the name, address,...

  5. Petition for Rulemaking to Evaluate Synergestic Effects of Pesticides during Registration and Registration Review

    EPA Pesticide Factsheets

    This petition from the Center for Biological Diversity asks that the Agency require all applicants and registrants to provide data on the potential synergistic effects of pesticides during the registration and registration review processes.

  6. A framework for deformable image registration validation in radiotherapy clinical applications

    PubMed Central

    Varadhan, Raj; Karangelis, Grigorios; Krishnan, Karthik; Hui, Susanta

    2013-01-01

    Quantitative validation of deformable image registration (DIR) algorithms is extremely difficult because of the complexity involved in constructing a deformable phantom that can duplicate various clinical scenarios. The purpose of this study is to describe a framework to test the accuracy of DIR based on computational modeling and evaluating using inverse consistency and other methods. Three clinically relevant organ deformations were created in prostate (distended rectum and rectal gas), head and neck (large neck flexion), and lung (inhale and exhale lung volumes with variable contrast enhancement) study sets. DIR was performed using both B-spline and diffeomorphic demons algorithms in the forward and inverse direction. A compositive accumulation of forward and inverse deformation vector fields was done to quantify the inverse consistency error (ICE). The anatomical correspondence of tumor and organs at risk was quantified by comparing the original RT structures with those obtained after DIR. Further, the physical characteristics of the deformation field, namely the Jacobian and harmonic energy, were computed to quantify the preservation of image topology and regularity of spatial transformation obtained in DIR. The ICE was comparable in prostate case but the B-spline algorithm had significantly better anatomical correspondence for rectum and prostate than diffeomorphic demons algorithm. The ICE was 6.5 mm for demons algorithm for head and neck case when compared to 0.7 mm for B-spline. Since the induced neck flexion was large, the average Dice similarity coefficient between both algorithms was only 0.87, 0.52, 0.81, and 0.67 for tumor, cord, parotids, and mandible, respectively. The B-spline algorithm accurately estimated deformations between images with variable contrast in our lung study, while diffeomorphic demons algorithm led to gross errors on structures affected by contrast variation. The proposed framework offers the application of known deformations on

  7. 9 CFR 121.7 - Registration and related security risk assessments.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ..., DEPARTMENT OF AGRICULTURE VIRUSES, SERUMS, TOXINS, AND ANALOGOUS PRODUCTS; ORGANISMS AND VECTORS POSSESSION... entity must submit the information requested in the registration application package (APHIS/CDC Form 1... information requested in the registration application package (APHIS/CDC Form 1) to APHIS or CDC, but not both...

  8. 75 FR 34111 - Notice of Intent to Suspend Certain Pesticide Registrations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-16

    ... issuance of a Data Call-In notice (DCI), which required the registrant of the affected pesticide product... registration of the affected product. Failure to comply with the data requirements of a DCI is a basis for... Data Due of Intent to Applicable DCI DCI Received DCI Date Suspend 67071-52 830.6317 Storage...

  9. Utilizing the Iterative Closest Point (ICP) algorithm for enhanced registration of high resolution surface models - more than a simple black-box application

    NASA Astrophysics Data System (ADS)

    Stöcker, Claudia; Eltner, Anette

    2016-04-01

    Advances in computer vision and digital photogrammetry (i.e. structure from motion) allow for fast and flexible high resolution data supply. Within geoscience applications and especially in the field of small surface topography, high resolution digital terrain models and dense 3D point clouds are valuable data sources to capture actual states as well as for multi-temporal studies. However, there are still some limitations regarding robust registration and accuracy demands (e.g. systematic positional errors) which impede the comparison and/or combination of multi-sensor data products. Therefore, post-processing of 3D point clouds can heavily enhance data quality. In this matter the Iterative Closest Point (ICP) algorithm represents an alignment tool which iteratively minimizes distances of corresponding points within two datasets. Even though tool is widely used; it is often applied as a black-box application within 3D data post-processing for surface reconstruction. Aiming for precise and accurate combination of multi-sensor data sets, this study looks closely at different variants of the ICP algorithm including sub-steps of point selection, point matching, weighting, rejection, error metric and minimization. Therefore, an agricultural utilized field was investigated simultaneously by terrestrial laser scanning (TLS) and unmanned aerial vehicle (UAV) sensors two times (once covered with sparse vegetation and once bare soil). Due to different perspectives both data sets show diverse consistency in terms of shadowed areas and thus gaps so that data merging would provide consistent surface reconstruction. Although photogrammetric processing already included sub-cm accurate ground control surveys, UAV point cloud exhibits an offset towards TLS point cloud. In order to achieve the transformation matrix for fine registration of UAV point clouds, different ICP variants were tested. Statistical analyses of the results show that final success of registration and therefore

  10. Real-time co-registration using novel ultrasound technology: ex vivo validation and in vivo applications

    PubMed Central

    Yang, Eric Y.; Polsani, Venkateshwar R.; Washburn, Michael J.; Zang, William; Hall, Anne L.; Virani, Salim S.; Hodge, Megan S.; Parker, Dan; Kerwin, William S.; Lawrie, Gerald M.; Garami, Zsolt; Ballantyne, Christie M.; Morrisett, Joel D.; Nambi, Vijay

    2011-01-01

    OBJECTIVES To evaluate whether a novel GPS-like position-sensing technology will enable accurate co-registration of images between imaging modalities. BACKGROUND Co-registration of images obtained by different imaging modalities will allow for comparison and fusion between imaging modalities, and therefore has significant clinical and research implications. We compared US and MR images of carotid endarterectomy (CEA) specimens using a novel position-sensing technology that uses an electromagnetic (EM) transmitter and sensors mounted on a US transducer. We then evaluated in vivo US-US and US-MRI co-registration. METHODS Thirteen CEA specimens underwent 3.0 Tesla MRI, after which images were uploaded to a LOGIQ E9 3D (GE Healthcare) US system and registered by identifying 2–3 common points. A similar method was used to evaluate US-MRI co-registration in patients with carotid atherosclerosis. For carotid intima-media thickness (C-IMT) measurements, ten volunteers underwent bilateral carotid US scans co-registered to 3D US maps created on the initial visit, with a repeat scan 2 days later. RESULTS For the CEA specimens, there was a mean 20 (standard error [SE] 2.0) frames per MRI slice. The mean frame difference, over 33 registration markers, between MR and US images for Readers 1 and 2 was −2.82 ± 19.32 (mean ± 95% confidence interval [CI]) frames and 2.09 ± 14.68 (mean ± 95% CI) frames, respectively. The US-MRI intraclass correlation coefficients (ICC) for the first and second readers were 0.995 and 0.997, respectively. For patients with carotid atherosclerosis, the mean US frames per MRI slice (9 [SE 2.3]) was within range of that observed with CEA specimens. Inter-visit, intra-reader, and inter-reader reproducibility of C-IMT measurements were consistently high (side-averaged ICC >0.9). CONCLUSION Accurate co-registration between US and other modalities is feasible with a GPS-like technology, which has significant clinical and research applicability. PMID

  11. Automatic Co-Registration of QuickBird Data for Change Detection Applications

    NASA Technical Reports Server (NTRS)

    Bryant, Nevin A.; Logan, Thomas L.; Zobrist, Albert L.

    2006-01-01

    This viewgraph presentation reviews the use Automatic Fusion of Image Data System (AFIDS) for Automatic Co-Registration of QuickBird Data to ascertain if changes have occurred in images. The process is outlined, and views from Iraq and Los Angelels are shown to illustrate the process.

  12. 9 CFR 201.86 - Brand inspection: Application for authorization, registration and filing of schedules, reciprocal...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... authorization, registration and filing of schedules, reciprocal arrangements, and maintenance of identity of... and filing of schedules, reciprocal arrangements, and maintenance of identity of consignments. (a... and will not result in duplication of charges or services. (d) Maintenance of identity of...

  13. 9 CFR 201.86 - Brand inspection: Application for authorization, registration and filing of schedules, reciprocal...

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... authorization, registration and filing of schedules, reciprocal arrangements, and maintenance of identity of... and filing of schedules, reciprocal arrangements, and maintenance of identity of consignments. (a... and will not result in duplication of charges or services. (d) Maintenance of identity of...

  14. 9 CFR 201.86 - Brand inspection: Application for authorization, registration and filing of schedules, reciprocal...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... authorization, registration and filing of schedules, reciprocal arrangements, and maintenance of identity of... and filing of schedules, reciprocal arrangements, and maintenance of identity of consignments. (a... and will not result in duplication of charges or services. (d) Maintenance of identity of...

  15. A Coupled Global Registration and Segmentation Framework With Application to Magnetic Resonance Prostate Imagery

    PubMed Central

    Sandhu, Romeil; Fichtinger, Gabor; Tannenbaum, Allen Robert

    2010-01-01

    Extracting the prostate from magnetic resonance (MR) imagery is a challenging and important task for medical image analysis and surgical planning. We present in this work a unified shape-based framework to extract the prostate from MR prostate imagery. In many cases, shape-based segmentation is a two-part problem. First, one must properly align a set of training shapes such that any variation in shape is not due to pose. Then segmentation can be performed under the constraint of the learnt shape. However, the general registration task of prostate shapes becomes increasingly difficult due to the large variations in pose and shape in the training sets, and is not readily handled through existing techniques. Thus, the contributions of this paper are twofold. We first explicitly address the registration problem by representing the shapes of a training set as point clouds. In doing so, we are able to exploit the more global aspects of registration via a certain particle filtering based scheme. In addition, once the shapes have been registered, a cost functional is designed to incorporate both the local image statistics as well as the learnt shape prior. We provide experimental results, which include several challenging clinical data sets, to highlight the algorithm’s capability of robustly handling supine/prone prostate registration and the overall segmentation task. PMID:20529727

  16. 17 CFR 240.17Ac2-1 - Application for registration of transfer agents.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Regulations Under the Securities Exchange Act of 1934 Nationally Recognized Statistical Rating Organizations... reported on Form TA-1 (§ 249b.100 of this chapter) becomes inaccurate, misleading, or incomplete, the... the information becomes inaccurate, misleading, or incomplete. (d) Every registration and amendment...

  17. PR notice 87-9. Notice to pesticide applicants, registrants and petitioners

    SciTech Connect

    Not Available

    1987-08-01

    The document is one in the series of Pesticide Regulatory Notices, usually called PR Notices, which supplement the laws and regulations governing pesticide regulation in the US. These notices clarify, interpret and explain regulatory requirements and policies. They are directed at pesticide registrants and other parties interested in detailed procedures of regulation.

  18. PR notice 87-10. Notice to pesticide applicants, registrants and petitioners

    SciTech Connect

    Not Available

    1987-10-01

    The document is one in the series of Pesticide Regulatory Notices, usually called PR Notices, which supplement the laws and regulations governing pesticide regulation in the US. These notices clarify, interpret and explain regulatory requirements and policies. They are directed at pesticide registrants and other parties interested in detailed procedures of regulation.

  19. 40 CFR 152.135 - Transfer of registration.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 24 2014-07-01 2014-07-01 false Transfer of registration. 152.135... PESTICIDE REGISTRATION AND CLASSIFICATION PROCEDURES Obligations and Rights of Registrants § 152.135 Transfer of registration. (a) A registrant may transfer the registration of a product to another...

  20. 40 CFR 152.135 - Transfer of registration.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 25 2013-07-01 2013-07-01 false Transfer of registration. 152.135... PESTICIDE REGISTRATION AND CLASSIFICATION PROCEDURES Obligations and Rights of Registrants § 152.135 Transfer of registration. (a) A registrant may transfer the registration of a product to another...

  1. Paying for pharmaceutical registration in developing countries.

    PubMed

    Kaplan, Warren A; Laing, Richard

    2003-09-01

    Fees charged by drug regulatory authorities (DRAs) may be used as a policy instrument to speed up regulatory approval, to encourage retention of quality staff and to stimulate introduction of generics versus new chemical entities. Often, the cost recovery function of these registration fees is not related to the true cost of the pharmaceutical regulatory process. In this paper, we scaled new drug registration fees of various DRAs to indices of economic development - the GNP per capita and the total government health expenditure per capita. Based on our analyses of 34 countries, most DRA registration fees for new drug applications for developing/non-OECD countries are less than the current GNP/capita of that country or are about US dollars 5000 for each US dollars 1000 spent per capita on healthcare. At present, each US dollars 1000 new drug registration fee for the developing/non-OECD countries analyzed corresponds to a total pharmaceutical market share of about US dollars 85 million. Our analyses further suggest little relationship between DRA registration fees and drug approval times in developing countries. The situation is complex, however, as policy tradeoffs are important to consider. Differential registration fees, presumably designed to encourage locally produced versus imported products, may violate international trade regulations. Moreover, certain DRA registration fees may provide perverse incentives for the pharmaceutical industry. Developing countries should require that DRA registration fees be based on accurate accounting of the cost of services provided. At present levels, these fees could be increased without disincentive to the pharmaceutical industry. For new drug registration fees, our analyses suggest that developing countries could charge between 1-5 times their GNP per capita or between US dollars 17000 and US dollars 80000 for each US dollars 1000 spent per capita on healthcare.

  2. SURFACE FLUID REGISTRATION OF CONFORMAL REPRESENTATION: APPLICATION TO DETECT DISEASE BURDEN AND GENETIC INFLUENCE ON HIPPOCAMPUS

    PubMed Central

    Shi, Jie; Thompson, Paul M.; Gutman, Boris; Wang, Yalin

    2013-01-01

    In this paper, we develop a new automated surface registration system based on surface conformal parameterization by holomorphic 1-forms, inverse consistentsurface fluid registration, and multivariate tensor-based morphometry (mTBM). First, we conformally map a surface onto a planar rectangle space with holomorphic 1-forms. Second, we compute surface conformal representation by combining its local conformal factor and mean curvature and linearly scale the dynamic range of the conformal representation to form the feature image of the surface. Third, we align the feature image with a chosen template image via the fluid image registration algorithm, which has been extended into the curvilinear coordinates to adjust for the distortion introduced by surface parameterization. The inverse consistent image registration algorithm is also incorporated in the system to jointly estimate the forward and inverse transformations between the study and template images. This alignment induces a corresponding deformation on the surface. We tested the system on Alzheimer's Disease Neuroimaging Initiative (ADNI) baseline dataset to study AD symptoms on hippocampus. In our system, by modeling a hippocampus as a 3D parametric surface, we nonlinearly registered each surface with a selected template surface. Then we used mTBM to analyze the morphometrydifference between diagnostic groups. Experimental results show that the new system has better performance than two publically available subcortical surface registration tools: FIRST and SPHARM. We also analyzed the genetic influence of the Apolipoprotein E ε4 allele (ApoE4),which is considered as the most prevalent risk factor for AD.Our work successfully detected statistically significant difference between ApoE4 carriers and non-carriers in both patients of mild cognitive impairment (MCI) and healthy control subjects. The results show evidence that the ApoE genotype may be associated with accelerated brain atrophy so that our workprovides

  3. Enhancement Of Optical Registration Signals Through Digital Signal Processing Techniques

    NASA Astrophysics Data System (ADS)

    Cote, Daniel R.; Lazo-Wasem, Jeanne

    1988-01-01

    Alignment and setup of lighography processes has largely been conducted on special test wafers. Actual product level optimization has been limited to manual techniques such as optical verniers. This is especially time consuming and prone to inconsistencies when the registration characteristics of lithographic systems are being measured. One key factor obstructing the use of automated metrology equipment on product level wafers is the inability to discern reliably, metrology features from the background noise and variations in optical registration signals. This is often the case for metal levels such as aluminum and tungsten. This paper discusses methods for enhancement of typical registration signals obtained from difficult semiconductor process levels. Brightfield and darkfield registration signals are obtained using a microscope and a 1024 element linear photodiode array. These signals are then digitized and stored on the hard disk of a computer. The techniques utilized include amplitude selective and adaptive and non-adaptive frequency domain filtering techniques. The effect of each of these techniques upon calculated registration values is analyzed by determining the positional variation of the center location of a two line registration feature. Plots of raw and processed signals obtained are presented as are plots of the power spectral density of ideal metrology feature signal and noise patterns. It is concluded that the proper application of digital signal processing (DSP) techniques to problematic optical registration signals greatly enhances the applicability of automated optical registration measurement techniques to difficult semiconductor process levels.

  4. 75 FR 74713 - Product Cancellation Order for Certain Pesticide Registrations; Correction

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-01

    ... being issued to rescind the cancellation of Sergeant's Pet Care Products' pesticide product, EPA Reg. No... correction notice do? This notice rescinds the cancellation of Sergeant's Pet Care Products' pesticide...

  5. 17 CFR 48.5 - Registration procedures.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 17 Commodity and Securities Exchanges 2 2014-04-01 2014-04-01 false Registration procedures. 48.5...) REGISTRATION OF FOREIGN BOARDS OF TRADE § 48.5 Registration procedures. (a) A foreign board of trade seeking registration with the Commission pursuant to this part must electronically file an application for...

  6. 7 CFR 800.34 - Registration fee.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 7 2011-01-01 2011-01-01 false Registration fee. 800.34 Section 800.34 Agriculture... ADMINISTRATION (FEDERAL GRAIN INSPECTION SERVICE), DEPARTMENT OF AGRICULTURE GENERAL REGULATIONS Registration § 800.34 Registration fee. An applicant shall submit the registration fee prescribed in § 800.71...

  7. 7 CFR 800.34 - Registration fee.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 7 2010-01-01 2010-01-01 false Registration fee. 800.34 Section 800.34 Agriculture... ADMINISTRATION (FEDERAL GRAIN INSPECTION SERVICE), DEPARTMENT OF AGRICULTURE GENERAL REGULATIONS Registration § 800.34 Registration fee. An applicant shall submit the registration fee prescribed in § 800.71...

  8. 7 CFR 800.34 - Registration fee.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 7 2013-01-01 2013-01-01 false Registration fee. 800.34 Section 800.34 Agriculture... ADMINISTRATION (FEDERAL GRAIN INSPECTION SERVICE), DEPARTMENT OF AGRICULTURE GENERAL REGULATIONS Registration § 800.34 Registration fee. An applicant shall submit the registration fee prescribed in § 800.71...

  9. 7 CFR 800.34 - Registration fee.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 7 2014-01-01 2014-01-01 false Registration fee. 800.34 Section 800.34 Agriculture... ADMINISTRATION (FEDERAL GRAIN INSPECTION SERVICE), DEPARTMENT OF AGRICULTURE GENERAL REGULATIONS Registration § 800.34 Registration fee. An applicant shall submit the registration fee prescribed in § 800.71...

  10. 7 CFR 800.34 - Registration fee.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 7 2012-01-01 2012-01-01 false Registration fee. 800.34 Section 800.34 Agriculture... ADMINISTRATION (FEDERAL GRAIN INSPECTION SERVICE), DEPARTMENT OF AGRICULTURE GENERAL REGULATIONS Registration § 800.34 Registration fee. An applicant shall submit the registration fee prescribed in § 800.71...

  11. Co-Registration of Multitemporal Uav Image Datasets for Monitoring Applications: a New Approach

    NASA Astrophysics Data System (ADS)

    Aicardi, I.; Nyapwere, N.; Nex, F.; Gerke, M.; Lingua, A. M.; Koeva, M. N.

    2016-06-01

    In the last years we have witnessed a rapid development of UAVs (Unmanned Aerial Vehicles), especially for image collection. One of the advantages is the possibility to perform high resolution and repeated flights in a cheap way to detect changes over time. Thus, dynamic scenes can be monitored acquiring image blocks in different epochs in a flexible way. Anyway, most of UAVs are not able to provide accurate direct geo-referencing information, so image blocks from different epochs still need to be co-registered to efficiently detect changes. This task is mostly completed using GCPs (Ground Control Points), although this approach is time consuming as manual intervention is needed. This paper aims at investigating new techniques to automate the co-registration of image blocks without the use of GCPs, just relying on an image based co-registration (IBCR) approach. The image alignment is initially performed on a reference (anchor) epoch and the registration of the following (slave) epochs is performed including some (anchor) images from the reference epoch with fixed external orientation parameters. This allows constraining the Bundle Block Adjustment of the slave epoch to be consistent with the reference one. The study involved the use of 10 multi-temporal image block over a large building construction site, and spanning a time frame of 2 years. Different tests have been performed for the reference image choice with a manual approach and then evaluating the reached accuracy. The performed tests on the chosen test site have shown that the accuracy of the proposed methodology provides results comparable to the common GCPs registration approach.

  12. 27 CFR 25.112 - Dealer registration.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2012-04-01 2012-04-01 false Dealer registration. 25..., DEPARTMENT OF THE TREASURY LIQUORS BEER Dealer Registration and Recordkeeping § 25.112 Dealer registration... appropriate TTB officer, will constitute the brewer's registration as a dealer at the brewery. Every...

  13. 27 CFR 25.112 - Dealer registration.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Dealer registration. 25..., DEPARTMENT OF THE TREASURY LIQUORS BEER Dealer Registration and Recordkeeping § 25.112 Dealer registration... appropriate TTB officer, will constitute the brewer's registration as a dealer at the brewery. Every...

  14. 27 CFR 25.112 - Dealer registration.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2013-04-01 2013-04-01 false Dealer registration. 25..., DEPARTMENT OF THE TREASURY ALCOHOL BEER Dealer Registration and Recordkeeping § 25.112 Dealer registration... appropriate TTB officer, will constitute the brewer's registration as a dealer at the brewery. Every...

  15. 27 CFR 25.112 - Dealer registration.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2011-04-01 2011-04-01 false Dealer registration. 25..., DEPARTMENT OF THE TREASURY LIQUORS BEER Dealer Registration and Recordkeeping § 25.112 Dealer registration... appropriate TTB officer, will constitute the brewer's registration as a dealer at the brewery. Every...

  16. 27 CFR 25.112 - Dealer registration.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2014-04-01 2014-04-01 false Dealer registration. 25..., DEPARTMENT OF THE TREASURY ALCOHOL BEER Dealer Registration and Recordkeeping § 25.112 Dealer registration... appropriate TTB officer, will constitute the brewer's registration as a dealer at the brewery. Every...

  17. Robust 3D–2D image registration: application to spine interventions and vertebral labeling in the presence of anatomical deformation

    PubMed Central

    Otake, Yoshito; Wang, Adam S; Stayman, J Webster; Uneri, Ali; Kleinszig, Gerhard; Vogt, Sebastian; Khanna, A Jay; Gokaslan, Ziya L; Siewerdsen, Jeffrey H

    2016-01-01

    same registration could be solved with 99 993% success in 6.3 s. The ability to register CT to fluoroscopy in a manner robust to patient deformation could be valuable in applications such as radiation therapy, interventional radiology, and an assistant to target localization (e.g., vertebral labeling) in image-guided spine surgery. PMID:24246386

  18. Robust 3D-2D image registration: application to spine interventions and vertebral labeling in the presence of anatomical deformation

    NASA Astrophysics Data System (ADS)

    Otake, Yoshito; Wang, Adam S.; Webster Stayman, J.; Uneri, Ali; Kleinszig, Gerhard; Vogt, Sebastian; Khanna, A. Jay; Gokaslan, Ziya L.; Siewerdsen, Jeffrey H.

    2013-12-01

    run) the same registration could be solved with 99.993% success in 6.3 s. The ability to register CT to fluoroscopy in a manner robust to patient deformation could be valuable in applications such as radiation therapy, interventional radiology, and an assistant to target localization (e.g., vertebral labeling) in image-guided spine surgery.

  19. Robust 3D-2D image registration: application to spine interventions and vertebral labeling in the presence of anatomical deformation.

    PubMed

    Otake, Yoshito; Wang, Adam S; Webster Stayman, J; Uneri, Ali; Kleinszig, Gerhard; Vogt, Sebastian; Khanna, A Jay; Gokaslan, Ziya L; Siewerdsen, Jeffrey H

    2013-12-07

    same registration could be solved with 99.993% success in 6.3 s. The ability to register CT to fluoroscopy in a manner robust to patient deformation could be valuable in applications such as radiation therapy, interventional radiology, and an assistant to target localization (e.g., vertebral labeling) in image-guided spine surgery.

  20. Orally inhaled drug performance testing for product development, registration, and quality control.

    PubMed

    Lastow, Orest; Svensson, Mårten

    2014-12-01

    A DPI can be split into three different modules; device, formulation, process. These are developed in parallel, and together with the user they provide the performance of an inhalation product. During product development, these modules are evolving and changing, whereas the requirements on an inhalation product are always expressed in terms of the performance of the final commercial product. To do performance testing during development when the product is not finished presents many challenges and can be confusing and misleading. During development, the performance of the final product is typically being predicted by testing ever changing prototypes. This article describes methods and approaches to manage such development and to, during development, provide relevant predictions of the in vitro and in vivo performances of the final product.

  1. Analysis to feature-based video stabilization/registration techniques within application of traffic data collection

    NASA Astrophysics Data System (ADS)

    Sadat, Mojtaba T.; Viti, Francesco

    2015-02-01

    Machine vision is rapidly gaining popularity in the field of Intelligent Transportation Systems. In particular, advantages are foreseen by the exploitation of Aerial Vehicles (AV) in delivering a superior view on traffic phenomena. However, vibration on AVs makes it difficult to extract moving objects on the ground. To partly overcome this issue, image stabilization/registration procedures are adopted to correct and stitch multiple frames taken of the same scene but from different positions, angles, or sensors. In this study, we examine the impact of multiple feature-based techniques for stabilization, and we show that SURF detector outperforms the others in terms of time efficiency and output similarity.

  2. 21 CFR 207.7 - Establishment registration and product listing for human blood and blood products and for medical...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... human blood and blood products and for medical devices. 207.7 Section 207.7 Food and Drugs FOOD AND DRUG... product listing for human blood and blood products and for medical devices. (a) Owners and operators of human blood and blood product establishments shall register and list their products with the Center...

  3. 21 CFR 207.7 - Establishment registration and product listing for human blood and blood products and for medical...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... human blood and blood products and for medical devices. 207.7 Section 207.7 Food and Drugs FOOD AND DRUG... product listing for human blood and blood products and for medical devices. (a) Owners and operators of human blood and blood product establishments shall register and list their products with the Center...

  4. 21 CFR 207.7 - Establishment registration and product listing for human blood and blood products and for medical...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... human blood and blood products and for medical devices. 207.7 Section 207.7 Food and Drugs FOOD AND DRUG... product listing for human blood and blood products and for medical devices. (a) Owners and operators of human blood and blood product establishments shall register and list their products with the Center...

  5. 21 CFR 207.7 - Establishment registration and product listing for human blood and blood products and for medical...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... human blood and blood products and for medical devices. 207.7 Section 207.7 Food and Drugs FOOD AND DRUG... product listing for human blood and blood products and for medical devices. (a) Owners and operators of human blood and blood product establishments shall register and list their products with the Center...

  6. 21 CFR 207.7 - Establishment registration and product listing for human blood and blood products and for medical...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... human blood and blood products and for medical devices. 207.7 Section 207.7 Food and Drugs FOOD AND DRUG... product listing for human blood and blood products and for medical devices. (a) Owners and operators of human blood and blood product establishments shall register and list their products with the Center...

  7. Fast automatic registration of images using the phase of a complex wavelet transform: application to proteome gels.

    PubMed

    Woodward, Andrew M; Rowland, Jem J; Kell, Douglas B

    2004-06-01

    Image registration describes the process of manipulating a distorted version of an image such that its pixels overlay the equivalent pixels in a clean, master or reference image. The need for it has assumed particular prominence in the analysis of images of electrophoretic gels used in the analysis of protein expression levels in living cells, but also has fundamental applications in most other areas of image analysis. Much of the positional information of a data feature is carried in the phase of a complex transform, so a complex transform allows explicit specification of the phase, and hence of the position of features in the image. Registration of a test gel to a reference gel is achieved by using a multiresolution movement map derived from the phase of a complex wavelet transform (the Q-shift wavelet transform) to dictate the warping directly via movement of the nodes of a Delaunay-triangulated mesh of points. This warping map is then applied to the original untransformed image such that the absolute magnitude of the spots remains unchanged. The technique is general to any type of image. Results are presented for a simple computer simulated gel, a simple real gel registration between similar "clean" gels with local warping vectors distributed about one main direction, a hard problem between a reference gel and a "dirty" test gel with multi-directional warping vectors and many artifacts, and some typical gels of present interest in post-genomic biology. The method compares favourably with others, since it is computationally rapid, effective and entirely automatic.

  8. 75 FR 34448 - Pesticides; Draft Guidance for Pesticide Registrants on False or Misleading Pesticide Product...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-17

    ... Brand Names; Extension of Comment Period AGENCY: Environmental Protection Agency (EPA). ACTION: Notice...) entitled ``False or Misleading Pesticide Product Brand Names.'' This document extends the comment period... Misleading Pesticide Product Brand Names.'' EPA is hereby extending the comment period, which was set to end...

  9. Evaluation and application of 3D lung warping and registration model using HRCT images

    NASA Astrophysics Data System (ADS)

    Fan, Li; Chen, Chang W.; Reinhardt, Joseph M.; Hoffman, Eric A.

    2001-05-01

    Image-based study of structure-function relationships is a challenging problem in that the structure or region of interest may vary in position and shape on images captured over time. Such variation may be caused by the change in body posture or the motion of breathing and heart beating. Therefore, the structure or region of interest should be registered before any further regional study can be carried out. In this paper, we propose a novel approach to study the structure-function relationship of ventilation using a previously developed 3D lung warping and registration model. First, we evaluate the effectiveness of the lung warping and registration model using a set of criteria, including apparent lung motion patterns and ground truths. Then, we study the ventilation by integrating the warping model with air content calibration. The warping model is applied to three CT lung data sets, obtained under volume control of FRC, 40% and 75% vital capacity (VC). Dense displacement fields are obtained to represent deformation between different lung volume steps. For any specific region of interest, we first register it between images over time using the dense displacement, and then estimate the corresponding regional inspired air content. Assessments include change of regional volume during inspiration, change of regional air content, and the distribution of regional ventilation. This is the first time that 3D warping of lung images is applied to assess clinically significant pulmonary functions.

  10. PRN 2008-1: Notice to Manufacturers, Producers, Formulators, and Registrants of Pesticide Products

    EPA Pesticide Factsheets

    This Notice presents EPA's guidance on optional environmental hazard label language for certain non-restricted use pesticide products intended for outdoor residential use. It clarifies language on how the user can avoid environmental contamination.

  11. 77 FR 18813 - Rescission of Previously Issued Cancellation Order for Methyl Parathion Product Registration

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-28

    ..., human health, and agricultural advocates; the chemical industry; pesticide users; and members of the... FR 43981), in relation to a Memorandum of Agreement where all methyl parathion products were...

  12. Visualization and registration of three-dimensional E-field distributions in annual-phased-array applicators.

    PubMed

    Wust, P; Fähling, H; Brünner, M; Nadobny, J; Jordan, A; Felix, R

    1999-04-01

    A testing system is presented allowing registration, digitization, and evaluation of three-dimensional power distributions rendered by annular-phased-array applicators in homogeneous liquid media. The system is based on a lamp phantom originally developed to visualize power distributions. Now the brightness distribution is registered via a charge-coupled device camera and transferred to a PC-based evaluation system outside the shielding room. An appropriate mechanical coupling of camera and sensor matrix probing the phantom was built in order to keep optical image conditions constant under movement. For visualization and evaluation commercially customized software was employed. The evaluation of the system shows the linearity between sensor signal and power density magnitude to be sufficient for evaluation and graphical representation of three-dimensional data sets. In a first practical application the testing system was employed to evaluate dependencies of power distributions as a function of frequency and phase settings on temperatures and, subsequently, the relevance of those results for clinical hyperthermia in a SIGMA-60 applicator (BSD-2000 system). Now, the system is ready to evaluate more complex multiantenna array applicators like the SIGMA-Eye applicator. The measuring system is particularly suitable for a fast comparison of APA applicators applied for a homogeneous medium. Implications for heterogeneous structures (like in patients) are then possible via modeling calculations.

  13. Multiattribute probabilistic prostate elastic registration (MAPPER): Application to fusion of ultrasound and magnetic resonance imaging

    SciTech Connect

    Sparks, Rachel Barratt, Dean; Nicolas Bloch, B.; Feleppa, Ernest; Moses, Daniel; Ponsky, Lee; Madabhushi, Anant

    2015-03-15

    Purpose: Transrectal ultrasound (TRUS)-guided needle biopsy is the current gold standard for prostate cancer diagnosis. However, up to 40% of prostate cancer lesions appears isoechoic on TRUS. Hence, TRUS-guided biopsy has a high false negative rate for prostate cancer diagnosis. Magnetic resonance imaging (MRI) is better able to distinguish prostate cancer from benign tissue. However, MRI-guided biopsy requires special equipment and training and a longer procedure time. MRI-TRUS fusion, where MRI is acquired preoperatively and then aligned to TRUS, allows for advantages of both modalities to be leveraged during biopsy. MRI-TRUS-guided biopsy increases the yield of cancer positive biopsies. In this work, the authors present multiattribute probabilistic postate elastic registration (MAPPER) to align prostate MRI and TRUS imagery. Methods: MAPPER involves (1) segmenting the prostate on MRI, (2) calculating a multiattribute probabilistic map of prostate location on TRUS, and (3) maximizing overlap between the prostate segmentation on MRI and the multiattribute probabilistic map on TRUS, thereby driving registration of MRI onto TRUS. MAPPER represents a significant advancement over the current state-of-the-art as it requires no user interaction during the biopsy procedure by leveraging texture and spatial information to determine the prostate location on TRUS. Although MAPPER requires manual interaction to segment the prostate on MRI, this step is performed prior to biopsy and will not substantially increase biopsy procedure time. Results: MAPPER was evaluated on 13 patient studies from two independent datasets—Dataset 1 has 6 studies acquired with a side-firing TRUS probe and a 1.5 T pelvic phased-array coil MRI; Dataset 2 has 7 studies acquired with a volumetric end-firing TRUS probe and a 3.0 T endorectal coil MRI. MAPPER has a root-mean-square error (RMSE) for expert selected fiducials of 3.36 ± 1.10 mm for Dataset 1 and 3.14 ± 0.75 mm for Dataset 2. State

  14. Multiview diffeomorphic registration: application to motion and strain estimation from 3D echocardiography.

    PubMed

    Piella, Gemma; De Craene, Mathieu; Butakoff, Constantine; Grau, Vicente; Yao, Cheng; Nedjati-Gilani, Shahrum; Penney, Graeme P; Frangi, Alejandro F

    2013-04-01

    This paper presents a new registration framework for quantifying myocardial motion and strain from the combination of multiple 3D ultrasound (US) sequences. The originality of our approach lies in the estimation of the transformation directly from the input multiple views rather than from a single view or a reconstructed compounded sequence. This allows us to exploit all spatiotemporal information available in the input views avoiding occlusions and image fusion errors that could lead to some inconsistencies in the motion quantification result. We propose a multiview diffeomorphic registration strategy that enforces smoothness and consistency in the spatiotemporal domain by modeling the 4D velocity field continuously in space and time. This 4D continuous representation considers 3D US sequences as a whole, therefore allowing to robustly cope with variations in heart rate resulting in different number of images acquired per cardiac cycle for different views. This contributes to the robustness gained by solving for a single transformation from all input sequences. The similarity metric takes into account the physics of US images and uses a weighting scheme to balance the contribution of the different views. It includes a comparison both between consecutive images and between a reference and each of the following images. The strain tensor is computed locally using the spatial derivatives of the reconstructed displacement fields. Registration and strain accuracy were evaluated on synthetic 3D US sequences with known ground truth. Experiments were also conducted on multiview 3D datasets of 8 volunteers and 1 patient treated by cardiac resynchronization therapy. Strain curves obtained from our multiview approach were compared to the single-view case, as well as with other multiview approaches. For healthy cases, the inclusion of several views improved the consistency of the strain curves and reduced the number of segments where a non-physiological strain pattern was

  15. 22 CFR 42.67 - Execution of application, registration, and fingerprinting.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... IMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Application for Immigrant Visas § 42.67...) Application fee. A fee is prescribed for each application for an immigrant visa. It shall be collected prior...-230. The applicant shall be required to read the Form DS-230, Application for Immigrant Visa and...

  16. 22 CFR 42.67 - Execution of application, registration, and fingerprinting.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... IMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Application for Immigrant Visas § 42.67...) Application fee. A fee is prescribed for each application for an immigrant visa. It shall be collected prior...-230. The applicant shall be required to read the Form DS-230, Application for Immigrant Visa and...

  17. 22 CFR 42.67 - Execution of application, registration, and fingerprinting.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... IMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Application for Immigrant Visas § 42.67...) Application fee. A fee is prescribed for each application for an immigrant visa. It shall be collected prior...-230. The applicant shall be required to read the Form DS-230, Application for Immigrant Visa and...

  18. Estimating the joint statistics of images using nonparametric windows with application to registration using mutual information.

    PubMed

    Dowson, Nicholas; Kadir, Timor; Bowden, Richard

    2008-10-01

    Recently, the Nonparametric (NP) Windows has been proposed to estimate the statistics of real 1D and 2D signals. NP Windows is accurate, because it is equivalent to sampling images at a high (infinite) resolution for an assumed interpolation model. This paper extends the proposed approach to consider joint distributions of image-pairs. Second, Green's Theorem is used to simplify the previous NP Windows algorithm. Finally, a resolution-aware NP Windows algorithm is proposed to improve robustness to relative scaling between an image pair. Comparative testing of 2D image registration was performed using translation-only and affine transformations. Although more expensive than other methods, NP Windows frequently demonstrated superior performance for bias (distance between ground truth and global maximum) and frequency of convergence. Unlike other methods, the number of samples and the number of bins have little effect on NP Windows and the prior selection of a kernel is not required.

  19. Mannosylerythritol lipids: production and applications.

    PubMed

    Morita, Tomotake; Fukuoka, Tokuma; Imura, Tomohiro; Kitamoto, Dai

    2015-01-01

    Mannosylerythritol lipids (MELs) are a glycolipid class of biosurfactants produced by a variety yeast and fungal strains that exhibit excellent interfacial and biochemical properties. MEL-producing fungi were identified using an efficient screening method for the glycolipid production and taxonomical classification on the basis of ribosomal RNA sequences. MEL production is limited primarily to the genus Pseudozyma, with significant variability among the MEL structures produced by each species. Outside of Pseudozyma, one recently isolated strain, Ustilago scitaminea, has been shown to exhibit abundant MEL-B production from sugarcane juice. Structural analyses of these compounds suggest a role for MELs in numerous cosmetic applications. MELs act as effective topical moisturizers and can repair damaged hair. Furthermore, these compounds have been shown to exhibit both protective and healing activities, to activate fibroblasts and papilla cells, and to act as natural antioxidants. In this review, we provide a brief summary of MEL research over the past few decades, focusing on the identification of MEL-producing fungi, the structural characterization of MELs, the use of alternative compounds as a primary carbon source, and the use of these compounds in cosmetic applications.

  20. How to Seek EPA Approval for Pesticide Applicator Soil Fumigation Exams

    EPA Pesticide Factsheets

    Registrants of soil fumigant products offer EPA-approved training for certified pesticide applicators. Although not required, state lead agencies (SLAs) may seek EPA’s approval and provide applicators with an alternative to registrant-sponsored training.

  1. 16 CFR 1130.8 - Requirements for Web site registration or alternative e-mail registration.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 16 Commercial Practices 2 2011-01-01 2011-01-01 false Requirements for Web site registration or... PRODUCTS § 1130.8 Requirements for Web site registration or alternative e-mail registration. (a) Link to registration page. The manufacturer's Web site, or other Web site established for the purpose of...

  2. 16 CFR 1130.8 - Requirements for Web site registration or alternative e-mail registration.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Requirements for Web site registration or... PRODUCTS (Eff. June 28, 2010) § 1130.8 Requirements for Web site registration or alternative e-mail registration. (a) Link to registration page. The manufacturer's Web site, or other Web site established for...

  3. 16 CFR 1130.7 - Requirements for Web site registration or alternative e-mail registration.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 16 Commercial Practices 2 2014-01-01 2014-01-01 false Requirements for Web site registration or... PRODUCTS § 1130.7 Requirements for Web site registration or alternative e-mail registration. (a) Link to registration page. The manufacturer's Web site, or other Web site established for the purpose of...

  4. 16 CFR 1130.8 - Requirements for Web site registration or alternative e-mail registration.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 16 Commercial Practices 2 2013-01-01 2013-01-01 false Requirements for Web site registration or... PRODUCTS § 1130.8 Requirements for Web site registration or alternative e-mail registration. (a) Link to registration page. The manufacturer's Web site, or other Web site established for the purpose of...

  5. Lectins: production and practical applications

    PubMed Central

    2010-01-01

    Lectins are proteins found in a diversity of organisms. They possess the ability to agglutinate erythrocytes with known carbohydrate specificity since they have at least one non-catalytic domain that binds reversibly to specific monosaccharides or oligosaccharides. This articles aims to review the production and practical applications of lectins. Lectins are isolated from their natural sources by chromatographic procedures or produced by recombinant DNA technology. The yields of animal lectins are usually low compared with the yields of plant lectins such as legume lectins. Lectins manifest a diversity of activities including antitumor, immunomodulatory, antifungal, HIV-1 reverse transcriptase inhibitory, and anti-insect activities, which may find practical applications. A small number of lectins demonstrate antibacterial and anti-nematode activities. PMID:20890754

  6. 14 CFR 47.16 - Temporary registration numbers.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 1 2012-01-01 2012-01-01 false Temporary registration numbers. 47.16... AIRCRAFT REGISTRATION General § 47.16 Temporary registration numbers. (a) Temporary registration numbers... Registry for as many temporary registration numbers as are necessary for his business. The application must...

  7. 27 CFR 24.53 - Amending the dealer registration.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2012-04-01 2012-04-01 false Amending the dealer registration. 24.53 Section 24.53 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE... proprietor must amend the application within the time period specified in subpart D of this part....

  8. 27 CFR 19.202 - Dealer registration.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2012-04-01 2012-04-01 false Dealer registration. 19..., DEPARTMENT OF THE TREASURY LIQUORS DISTILLED SPIRITS PLANTS Dealer Registration and Recordkeeping § 19.202 Dealer registration. Every proprietor that sells or offers for sale any alcoholic product...

  9. 27 CFR 447.31 - Registration requirement.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 3 2014-04-01 2014-04-01 false Registration requirement. 447.31 Section 447.31 Alcohol, Tobacco Products, and Firearms BUREAU OF ALCOHOL, TOBACCO, FIREARMS... IMPLEMENTS OF WAR Registration § 447.31 Registration requirement. Persons engaged in the business, in...

  10. 27 CFR 447.31 - Registration requirement.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 3 2011-04-01 2010-04-01 true Registration requirement. 447.31 Section 447.31 Alcohol, Tobacco Products, and Firearms BUREAU OF ALCOHOL, TOBACCO, FIREARMS... IMPLEMENTS OF WAR Registration § 447.31 Registration requirement. Persons engaged in the business, in...

  11. 27 CFR 19.202 - Dealer registration.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2013-04-01 2013-04-01 false Dealer registration. 19..., DEPARTMENT OF THE TREASURY ALCOHOL DISTILLED SPIRITS PLANTS Dealer Registration and Recordkeeping § 19.202 Dealer registration. Every proprietor that sells or offers for sale any alcoholic product...

  12. 27 CFR 447.31 - Registration requirement.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 3 2010-04-01 2010-04-01 false Registration requirement. 447.31 Section 447.31 Alcohol, Tobacco Products, and Firearms BUREAU OF ALCOHOL, TOBACCO, FIREARMS... IMPLEMENTS OF WAR Registration § 447.31 Registration requirement. Persons engaged in the business, in...

  13. 27 CFR 19.202 - Dealer registration.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2014-04-01 2014-04-01 false Dealer registration. 19..., DEPARTMENT OF THE TREASURY ALCOHOL DISTILLED SPIRITS PLANTS Dealer Registration and Recordkeeping § 19.202 Dealer registration. Every proprietor that sells or offers for sale any alcoholic product...

  14. 27 CFR 447.31 - Registration requirement.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 3 2013-04-01 2013-04-01 false Registration requirement. 447.31 Section 447.31 Alcohol, Tobacco Products, and Firearms BUREAU OF ALCOHOL, TOBACCO, FIREARMS... IMPLEMENTS OF WAR Registration § 447.31 Registration requirement. Persons engaged in the business, in...

  15. 27 CFR 19.50 - Dealer registration.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Dealer registration. 19.50... OF THE TREASURY LIQUORS DISTILLED SPIRITS PLANTS Dealer Registration and Recordkeeping § 19.50 Dealer registration. Every proprietor who sells or offers for sale any alcoholic product (distilled spirits, wines,...

  16. 27 CFR 19.202 - Dealer registration.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2011-04-01 2011-04-01 false Dealer registration. 19..., DEPARTMENT OF THE TREASURY LIQUORS DISTILLED SPIRITS PLANTS Dealer Registration and Recordkeeping § 19.202 Dealer registration. Every proprietor that sells or offers for sale any alcoholic product...

  17. 27 CFR 447.31 - Registration requirement.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 3 2012-04-01 2010-04-01 true Registration requirement. 447.31 Section 447.31 Alcohol, Tobacco Products, and Firearms BUREAU OF ALCOHOL, TOBACCO, FIREARMS... IMPLEMENTS OF WAR Registration § 447.31 Registration requirement. Persons engaged in the business, in...

  18. Nonrigid registration with free-form deformation model of multilevel uniform cubic B-splines: application to image registration and distortion correction of spectral image cubes.

    PubMed

    Eckhard, Timo; Eckhard, Jia; Valero, Eva M; Nieves, Juan Luis

    2014-06-10

    In spectral imaging, spatial and spectral information of an image scene are combined. There exist several technologies that allow the acquisition of this kind of data. Depending on the optical components used in the spectral imaging systems, misalignment between image channels can occur. Further, the projection of some systems deviates from that of a perfect optical lens system enough that a distortion of scene content in the images becomes apparent to the observer. Correcting distortion and misalignment can be complicated for spectral image data if they are different at each image channel. In this work, we propose an image registration and distortion correction scheme for spectral image cubes that is based on a free-form deformation model of uniform cubic B-splines with multilevel grid refinement. This scheme is adaptive with respect to image size, degree of misalignment, and degree of distortion, and in that sense is superior to previous approaches. We support our proposed scheme with empirical data from a Bragg-grating-based hyperspectral imager, for which a registration accuracy of approximately one pixel was achieved.

  19. 22 CFR 42.67 - Execution of application, registration, and fingerprinting.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... response. When an automated database name check query indicates that an immigrant applicant may have a criminal history record indexed in an NCIC database, the applicant shall be required to have a set...

  20. Handling topological changes during elastic registration : Application to augmented reality in laparoscopic surgery.

    PubMed

    Paulus, Christoph J; Haouchine, Nazim; Kong, Seong-Ho; Soares, Renato Vianna; Cazier, David; Cotin, Stephane

    2017-03-01

    Locating the internal structures of an organ is a critical aspect of many surgical procedures. Minimally invasive surgery, associated with augmented reality techniques, offers the potential to visualize inner structures, allowing for improved analysis, depth perception or for supporting planning and decision systems. Most of the current methods dealing with rigid or non-rigid augmented reality make the assumption that the topology of the organ is not modified. As surgery relies essentially on cutting and dissection of anatomical structures, such methods are limited to the early stages of the surgery. We solve this shortcoming with the introduction of a method for physics-based elastic registration using a single view from a monocular camera. Singularities caused by topological changes are detected and propagated to the preoperative model. This significantly improves the coherence between the actual laparoscopic view and the model and provides added value in terms of navigation and decision-making, e.g., by overlaying the internal structures of an organ on the laparoscopic view. Our real-time augmentation method is assessed on several scenarios, using synthetic objects and real organs. In all cases, the impact of our approach is demonstrated, both qualitatively and quantitatively ( http://www.open-cas.org/?q=PaulusIJCARS16 ). The presented approach tackles the challenge of localizing internal structures throughout a complete surgical procedure, even after surgical cuts. This information is crucial for surgeons to improve the outcome for their surgical procedure and avoid complications.

  1. Ultrasound calibration using intensity-based image registration: for application in cardiac catheterization procedures

    NASA Astrophysics Data System (ADS)

    Ma, Y. L.; Rhode, K. S.; Gao, G.; King, A. P.; Chinchapatnam, P.; Schaeffter, T.; Hawkes, D. J.; Razavi, R.; Penney, G. P.

    2008-03-01

    We present a novel method to calibrate a 3D ultrasound probe which has a 2D transducer array. By optically tracking a calibrated 3D probe we are able to produce extended field of view 3D ultrasound images. Tracking also enables us to register our ultrasound images to other tracked and calibrated surgical instruments or to other tracked and calibrated imaging devices. Our method applies rigid intensity-based image registration to three or more ultrasound images. These images can either be of a simple phantom, or could potentially be images of the patient. In this latter case we would have an automated calibration system which required no phantom, no image segmentation and was optimized to the patient's ultrasound characteristics i.e. speed of sound. We have carried out experiments using a simple calibration phantom and with ultrasound images of a volunteer's liver. Results are compared to an independent gold-standard. These showed our method to be accurate to 1.43mm using the phantom images and 1.56mm using the liver data, which is slightly better than the traditional point-based calibration method (1.7mm in our experiments).

  2. 75 FR 71376 - Simplified Network Application Processing System, On-Line Registration and Account Maintenance

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-23

    ... Bureau of Industry and Security 15 CFR Part 748 RIN 0694-AE98 Simplified Network Application Processing... and CIV (herein ``work items'') electronically via BIS's Simplified Network Application Processing... from BIS. BIS implemented a revised version of its Simplified Network Applications Processing System...

  3. Control of product batches (before and after registration). The French approach.

    PubMed

    Vannier, P

    1992-01-01

    The issue of investigation into vaccine files and control in general has always been a delicate one. There are considerable economic and medical interests. The supervisor should not then thwart a step towards progress and should not appear as an economic brake. Yet he should guarantee to the users a certain quality in the marketed biological products. According to these principles, recommendations have been formulated to indicate tests that should be realized by manufacturers and related in files of request for Marketing Authorization. Consequently the level of requirements may seem quite high in France. But partners involved in the investigation of files and in vaccine controls as well as those who are concerned with the marketing of new biological products should guarantee their quality. In addition to investigating the file, controls are undertaken in France by State laboratories which specialize in a particular species. They are also applied research laboratories. These controls aim at checking the manufacturers' results. In France no systematic control is undertaken on successive vaccine batches before marketing. Controls are undertaken at random if information coming from users gives rise to suspicion about a vaccine or batch of vaccines which are causing problems. However systematic controls should be undertaken by a private or State laboratory for imported batches. In future, only control results will probably be required. However batch-to-batch controls are undertaken by a state laboratory for rabies vaccines and tuberculin. In conclusion, in France we favour controls before Marketing Authorization together with high specifications for manufacturers. State batch-to-batch control is not undertaken since present means do not encourage such a procedure, the interest of which are not obvious; furthermore, this procedure remains very restricting for manufacturers.

  4. Applications, Acceptances and Registrations, Spring 1976. Student Flow Project, Report No. 7.

    ERIC Educational Resources Information Center

    Hawaii Univ., Honolulu. Community Coll. System.

    As part of a longitudinal study of student progress through the Hawaii community colleges, spring 1976 applications to the system were studied. The total number of applications received numbered 6,692 (3,924 new students, and 2,768 transfers), about half the number received for the fall semester (13,631). The colleges accepted 90 percent of the…

  5. Towards operational multisensor registration

    NASA Technical Reports Server (NTRS)

    Rignot, Eric J. M.; Kwok, Ronald; Curlander, John C.

    1991-01-01

    To use data from a number of different remote sensors in a synergistic manner, a multidimensional analysis of the data is necessary. However, prior to this analysis, processing to correct for the systematic geometric distortion characteristic of each sensor is required. Furthermore, the registration process must be fully automated to handle a large volume of data and high data rates. A conceptual approach towards an operational multisensor registration algorithm is presented. The performance requirements of the algorithm are first formulated given the spatially, temporally, and spectrally varying factors that influence the image characteristics and the science requirements of various applications. Several registration techniques that fit within the structure of this algorithm are also presented. Their performance was evaluated using a multisensor test data set assembled from LANDSAT TM, SEASAT, SIR-B, Thermal Infrared Multispectral Scanner (TIMS), and SPOT sensors.

  6. 78 FR 33447 - Draft Applications for Sealed Source and Device Evaluation and Registration

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-04

    ... radioactive materials, protection of sensitive information, and changes in regulatory policies and practices..., ``Consolidated Guidance about Materials Licenses: Applications for Sealed Source and Device Evaluation and... INFORMATION CONTACT: Tomas Herrera, Office of Federal and State Materials and Environmental ]...

  7. 9 CFR 201.86 - Brand inspection: Application for authorization, registration and filing of schedules, reciprocal...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... characteristics of livestock are received from the same State, a hearing will be held to determine which applicant..., shrinkage in weight, or other avoidable losses. (Approved by the Office of Management and Budget under...

  8. 47 CFR 64.1195 - Registration requirement.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 3 2012-10-01 2012-10-01 false Registration requirement. 64.1195 Section 64....1195 Registration requirement. (a) Applicability. A telecommunications carrier that will provide interstate telecommunications service shall file the registration information described in paragraph (b)...

  9. 47 CFR 64.1195 - Registration requirement.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 3 2010-10-01 2010-10-01 false Registration requirement. 64.1195 Section 64....1195 Registration requirement. (a) Applicability. A telecommunications carrier that will provide interstate telecommunications service shall file the registration information described in paragraph (b)...

  10. 47 CFR 64.1195 - Registration requirement.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 3 2011-10-01 2011-10-01 false Registration requirement. 64.1195 Section 64....1195 Registration requirement. (a) Applicability. A telecommunications carrier that will provide interstate telecommunications service shall file the registration information described in paragraph (b)...

  11. 47 CFR 64.1195 - Registration requirement.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 3 2013-10-01 2013-10-01 false Registration requirement. 64.1195 Section 64....1195 Registration requirement. (a) Applicability. A telecommunications carrier that will provide interstate telecommunications service shall file the registration information described in paragraph (b)...

  12. 47 CFR 64.1195 - Registration requirement.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 3 2014-10-01 2014-10-01 false Registration requirement. 64.1195 Section 64....1195 Registration requirement. (a) Applicability. A telecommunications carrier that will provide interstate telecommunications service shall file the registration information described in paragraph (b)...

  13. 14 CFR 47.15 - Registration number.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 1 2014-01-01 2014-01-01 false Registration number. 47.15 Section 47.15 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRCRAFT REGISTRATION General § 47.15 Registration number. (a) Number required. An applicant for aircraft...

  14. The comparative accuracy of the ROSA stereotactic robot across a wide range of clinical applications and registration techniques.

    PubMed

    Brandmeir, Nicholas J; Savaliya, Sandip; Rohatgi, Pratik; Sather, Michael

    2017-05-08

    Robot-assisted stereotactic neurosurgery is an emerging technology with a growing range of applications. The ROSA system is a robotic stereotactic system that has been shown to be accurate in laboratory studies and large case series. The goal of this study was to examine the accuracy of the ROSA across different registration methods as well as different clinical applications. Sixteen patients with one hundred and seventeen stereotactic trajectories were examined. Accuracy was compared by measuring the distance between the trajectory target and the actual termination of the device as determined by imaging. Entry error and angular deviation were also measured. Variables included bone fiducials vs. laser facial scanning, the clinical indication for stereotactic surgery, and the effect of lead deflection on accuracy. Bone fiducials did not offer an accuracy benefit over laser facial scanning (mean target error 4.5-3.9 mm, p = 0.34) in these clinical scenarios. Laser interstitial thermal therapy, responsive neurostimulation, and stereo electroencephalography were equally accurate when placed by the ROSA (mean target error 4.4-4.3-4.0 mm, respectively, p = 0.69). Deflection did not affect lead accuracy (mean target error 4.4-3.9 mm, p = 0.11). Similar results are seen for entry error and angular deviation. ROSA is a highly accurate stereotactic system. Laser facial scanning provides the same accuracy as bone fiducials in these stereotactic applications. The ROSA is equally accurate across a wide spectrum of applications. The ROSA is effective at limiting lead deflection, and when it does occur, it does not impact target accuracy in a significant way.

  15. 27 CFR 26.171 - Claimant registration.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2011-04-01 2011-04-01 false Claimant registration. 26... Drawback on Eligible Articles From Puerto Rico § 26.171 Claimant registration. Any person filing claim for... as a nonbeverage domestic drawback claimant. Registration will be accomplished when the...

  16. 9 CFR 320.5 - Registration.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 9 Animals and Animal Products 2 2014-01-01 2014-01-01 false Registration. 320.5 Section 320.5... CERTIFICATION RECORDS, REGISTRATION, AND REPORTS § 320.5 Registration. (a) Except as provided in paragraph (c... therein upon said effective date. All information submitted shall be current and correct. The...

  17. 27 CFR 24.52 - Dealer registration.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2011-04-01 2011-04-01 false Dealer registration. 24.52... OF THE TREASURY LIQUORS WINE Administrative and Miscellaneous Provisions Dealer Registration and Recordkeeping § 24.52 Dealer registration. Every proprietor who sells or offers for sale any alcohol...

  18. 27 CFR 26.307 - Claimant registration.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Claimant registration. 26... Drawback on Eligible Articles From the Virgin Islands § 26.307 Claimant registration. Any person filing... must register annually as a nonbeverage domestic drawback claimant. Registration will be...

  19. 27 CFR 26.171 - Claimant registration.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Claimant registration. 26... Drawback on Eligible Articles From Puerto Rico § 26.171 Claimant registration. Any person filing claim for... as a nonbeverage domestic drawback claimant. Registration will be accomplished when the...

  20. 27 CFR 24.52 - Dealer registration.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2013-04-01 2013-04-01 false Dealer registration. 24.52... OF THE TREASURY ALCOHOL WINE Administrative and Miscellaneous Provisions Dealer Registration and Recordkeeping § 24.52 Dealer registration. Every proprietor who sells or offers for sale any alcohol...

  1. 9 CFR 320.5 - Registration.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 9 Animals and Animal Products 2 2012-01-01 2012-01-01 false Registration. 320.5 Section 320.5... CERTIFICATION RECORDS, REGISTRATION, AND REPORTS § 320.5 Registration. (a) Except as provided in paragraph (c... therein upon said effective date. All information submitted shall be current and correct. The...

  2. 27 CFR 24.52 - Dealer registration.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2014-04-01 2014-04-01 false Dealer registration. 24.52... OF THE TREASURY ALCOHOL WINE Administrative and Miscellaneous Provisions Dealer Registration and Recordkeeping § 24.52 Dealer registration. Every proprietor who sells or offers for sale any alcohol...

  3. 27 CFR 24.52 - Dealer registration.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Dealer registration. 24.52... OF THE TREASURY LIQUORS WINE Administrative and Miscellaneous Provisions Dealer Registration and Recordkeeping § 24.52 Dealer registration. Every proprietor who sells or offers for sale any alcohol...

  4. 27 CFR 26.171 - Claimant registration.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2012-04-01 2012-04-01 false Claimant registration. 26... Drawback on Eligible Articles From Puerto Rico § 26.171 Claimant registration. Any person filing claim for... as a nonbeverage domestic drawback claimant. Registration will be accomplished when the...

  5. 27 CFR 26.307 - Claimant registration.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2011-04-01 2011-04-01 false Claimant registration. 26... Drawback on Eligible Articles From the Virgin Islands § 26.307 Claimant registration. Any person filing... must register annually as a nonbeverage domestic drawback claimant. Registration will be...

  6. 9 CFR 320.5 - Registration.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 9 Animals and Animal Products 2 2011-01-01 2011-01-01 false Registration. 320.5 Section 320.5... CERTIFICATION RECORDS, REGISTRATION, AND REPORTS § 320.5 Registration. (a) Except as provided in paragraph (c... therein upon said effective date. All information submitted shall be current and correct. The...

  7. 9 CFR 320.5 - Registration.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 9 Animals and Animal Products 2 2013-01-01 2013-01-01 false Registration. 320.5 Section 320.5... CERTIFICATION RECORDS, REGISTRATION, AND REPORTS § 320.5 Registration. (a) Except as provided in paragraph (c... therein upon said effective date. All information submitted shall be current and correct. The...

  8. 27 CFR 26.171 - Claimant registration.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2013-04-01 2013-04-01 false Claimant registration. 26... Drawback on Eligible Articles From Puerto Rico § 26.171 Claimant registration. Any person filing claim for... as a nonbeverage domestic drawback claimant. Registration will be accomplished when the...

  9. 27 CFR 26.307 - Claimant registration.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2014-04-01 2014-04-01 false Claimant registration. 26... Drawback on Eligible Articles From the Virgin Islands § 26.307 Claimant registration. Any person filing... must register annually as a nonbeverage domestic drawback claimant. Registration will be...

  10. 27 CFR 26.307 - Claimant registration.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2013-04-01 2013-04-01 false Claimant registration. 26... Drawback on Eligible Articles From the Virgin Islands § 26.307 Claimant registration. Any person filing... must register annually as a nonbeverage domestic drawback claimant. Registration will be...

  11. 27 CFR 26.171 - Claimant registration.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2014-04-01 2014-04-01 false Claimant registration. 26... Drawback on Eligible Articles From Puerto Rico § 26.171 Claimant registration. Any person filing claim for... as a nonbeverage domestic drawback claimant. Registration will be accomplished when the...

  12. 27 CFR 24.52 - Dealer registration.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2012-04-01 2012-04-01 false Dealer registration. 24.52... OF THE TREASURY LIQUORS WINE Administrative and Miscellaneous Provisions Dealer Registration and Recordkeeping § 24.52 Dealer registration. Every proprietor who sells or offers for sale any alcohol...

  13. NPAR- products, applications and closure

    SciTech Connect

    Vora, J.P.

    1995-04-01

    Almost a decade ago the Office of Nuclear Regulatory Research (RES) developed and implemented a comprehensive research program (NUREG-1144) widely known as NPAR or Nuclear Plant Aging Research. The NPAR program is a structured research program specifically oriented to understanding significant age-related degradation mechanisms and their long term effects on properties and performance of important components and systems and ways to mitigate detrimental effects of aging. It provided a road map and a phased approach to research that is applicable to any structure, system, or component of interest. This hardware-oriented engineering research program led the industry worldwide and communicated a need to understand and manage age-related degradation effects in selected but important structures and components. At the conclusion (1995) of the NPAR program, 22 electrical and mechanical components, 13 safety-related systems, and 10 special topics will have been studied and results summarized in 160 technical reports. This reference library of information listed and summarized in NUREG-1377, Rev. No. 4 provides a foundation upon which individual programs can be built for the specific needs of a utility, a regulator, or equipment manufacturers. During the life of the NPAR program, it has provided technical bases and support for license renewal, codes and standards, resolution of generic safety issues, information notices, regulatory guides and the standard Review Plan, as well as the Office of Nuclear Reactor Regulation and The NRC Regions. All ongoing NPAR activities will either be completed or terminated by the end of 1995. No new initiative will be undertaken. This paper summarizes NPAR products and accomplishments, application of the research results, and its status and closure.

  14. 40 CFR 159.160 - Obligations of former registrants.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ....160 Section 159.160 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE... submit information concerning the registration of a pesticide product previously held by the registrant... registration of the pesticide product has been canceled or transferred to another registrant, with...

  15. 40 CFR 159.160 - Obligations of former registrants.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ....160 Section 159.160 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE... submit information concerning the registration of a pesticide product previously held by the registrant... registration of the pesticide product has been canceled or transferred to another registrant, with...

  16. 40 CFR 159.160 - Obligations of former registrants.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ....160 Section 159.160 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE... submit information concerning the registration of a pesticide product previously held by the registrant... registration of the pesticide product has been canceled or transferred to another registrant, with...

  17. 40 CFR 159.160 - Obligations of former registrants.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ....160 Section 159.160 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE... submit information concerning the registration of a pesticide product previously held by the registrant... registration of the pesticide product has been canceled or transferred to another registrant, with...

  18. 40 CFR 159.160 - Obligations of former registrants.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ....160 Section 159.160 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE... submit information concerning the registration of a pesticide product previously held by the registrant... registration of the pesticide product has been canceled or transferred to another registrant, with...

  19. Simultaneous 3D–2D image registration and C-arm calibration: Application to endovascular image-guided interventions

    SciTech Connect

    Mitrović, Uroš; Pernuš, Franjo; Likar, Boštjan; Špiclin, Žiga

    2015-11-15

    Purpose: Three-dimensional to two-dimensional (3D–2D) image registration is a key to fusion and simultaneous visualization of valuable information contained in 3D pre-interventional and 2D intra-interventional images with the final goal of image guidance of a procedure. In this paper, the authors focus on 3D–2D image registration within the context of intracranial endovascular image-guided interventions (EIGIs), where the 3D and 2D images are generally acquired with the same C-arm system. The accuracy and robustness of any 3D–2D registration method, to be used in a clinical setting, is influenced by (1) the method itself, (2) uncertainty of initial pose of the 3D image from which registration starts, (3) uncertainty of C-arm’s geometry and pose, and (4) the number of 2D intra-interventional images used for registration, which is generally one and at most two. The study of these influences requires rigorous and objective validation of any 3D–2D registration method against a highly accurate reference or “gold standard” registration, performed on clinical image datasets acquired in the context of the intervention. Methods: The registration process is split into two sequential, i.e., initial and final, registration stages. The initial stage is either machine-based or template matching. The latter aims to reduce possibly large in-plane translation errors by matching a projection of the 3D vessel model and 2D image. In the final registration stage, four state-of-the-art intrinsic image-based 3D–2D registration methods, which involve simultaneous refinement of rigid-body and C-arm parameters, are evaluated. For objective validation, the authors acquired an image database of 15 patients undergoing cerebral EIGI, for which accurate gold standard registrations were established by fiducial marker coregistration. Results: Based on target registration error, the obtained success rates of 3D to a single 2D image registration after initial machine-based and

  20. Simultaneous 3D-2D image registration and C-arm calibration: Application to endovascular image-guided interventions.

    PubMed

    Mitrović, Uroš; Pernuš, Franjo; Likar, Boštjan; Špiclin, Žiga

    2015-11-01

    Three-dimensional to two-dimensional (3D-2D) image registration is a key to fusion and simultaneous visualization of valuable information contained in 3D pre-interventional and 2D intra-interventional images with the final goal of image guidance of a procedure. In this paper, the authors focus on 3D-2D image registration within the context of intracranial endovascular image-guided interventions (EIGIs), where the 3D and 2D images are generally acquired with the same C-arm system. The accuracy and robustness of any 3D-2D registration method, to be used in a clinical setting, is influenced by (1) the method itself, (2) uncertainty of initial pose of the 3D image from which registration starts, (3) uncertainty of C-arm's geometry and pose, and (4) the number of 2D intra-interventional images used for registration, which is generally one and at most two. The study of these influences requires rigorous and objective validation of any 3D-2D registration method against a highly accurate reference or "gold standard" registration, performed on clinical image datasets acquired in the context of the intervention. The registration process is split into two sequential, i.e., initial and final, registration stages. The initial stage is either machine-based or template matching. The latter aims to reduce possibly large in-plane translation errors by matching a projection of the 3D vessel model and 2D image. In the final registration stage, four state-of-the-art intrinsic image-based 3D-2D registration methods, which involve simultaneous refinement of rigid-body and C-arm parameters, are evaluated. For objective validation, the authors acquired an image database of 15 patients undergoing cerebral EIGI, for which accurate gold standard registrations were established by fiducial marker coregistration. Based on target registration error, the obtained success rates of 3D to a single 2D image registration after initial machine-based and template matching and final registration

  1. Co-registration of speech production datasets from electromagnetic articulography and real-time magnetic resonance imaging

    PubMed Central

    Kim, Jangwon; Lammert, Adam C.; Kumar Ghosh, Prasanta; Narayanan, Shrikanth S.

    2014-01-01

    This paper describes a spatio-temporal registration approach for speech articulation data obtained from electromagnetic articulography (EMA) and real-time Magnetic Resonance Imaging (rtMRI). This is motivated by the potential for combining the complementary advantages of both types of data. The registration method is validated on EMA and rtMRI datasets obtained at different times, but using the same stimuli. The aligned corpus offers the advantages of high temporal resolution (from EMA) and a complete mid-sagittal view (from rtMRI). The co-registration also yields optimum placement of EMA sensors as articulatory landmarks on the magnetic resonance images, thus providing richer spatio-temporal information about articulatory dynamics. PMID:25234914

  2. 78 FR 22876 - Rodenticides; Notice of Intent To Cancel Registrations of, and Notice of Denial of Applications...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-17

    ... for, Certain Rodenticide Bait Products AGENCY: United States Environmental Protection Agency. ACTION... Federal Insecticide, Fungicide, and Rodenticide Act, 7 U.S.C. 136d, and Section 164.8 of the associated... of Application for, Certain Rodenticide Bait Products, published in the Federal Register on...

  3. 17 CFR 3.44 - Temporary licensing of applicants for guaranteed introducing broker registration.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... fingerprints of the applicant, if a sole proprietor, and of each principal (including each branch office manager) thereof on fingerprint cards provided by the National Futures Association for that purpose. (b... any principal (including any branch office manager) thereof or for the resubmission of a...

  4. 17 CFR 3.44 - Temporary licensing of applicants for guaranteed introducing broker registration.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ..., as appropriate, is accurate and complete; and (5) The fingerprints of the applicant, if a sole proprietor, and of each principal (including each branch office manager) thereof on fingerprint cards... fingerprint card. (b) The effective date of a guarantee agreement filed in accordance with paragraph (a)(1)...

  5. 17 CFR 3.44 - Temporary licensing of applicants for guaranteed introducing broker registration.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... fingerprints of the applicant, if a sole proprietor, and of each principal (including each branch office manager) thereof on fingerprint cards provided by the National Futures Association for that purpose... Commission is not required to submit a fingerprint card. (b) The effective date of a guarantee...

  6. 17 CFR 3.44 - Temporary licensing of applicants for guaranteed introducing broker registration.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... fingerprints of the applicant, if a sole proprietor, and of each principal (including each branch office manager) thereof on fingerprint cards provided by the National Futures Association for that purpose... Commission is not required to submit a fingerprint card. (b) The effective date of a guarantee...

  7. 49 CFR 107.705 - Registrations, reports, and applications for approval.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... approval. 107.705 Section 107.705 Transportation Other Regulations Relating to Transportation PIPELINE AND... Hazardous Materials Safety (Attention: Approvals, PHH-32), Pipeline and Hazardous Materials Safety... the applicant, will issue a written extension to permit operation under the terms of the...

  8. 49 CFR 107.705 - Registrations, reports, and applications for approval.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... approval. 107.705 Section 107.705 Transportation Other Regulations Relating to Transportation PIPELINE AND... Hazardous Materials Safety (Attention: Approvals, PHH-32), Pipeline and Hazardous Materials Safety... the applicant, will issue a written extension to permit operation under the terms of the...

  9. 49 CFR 107.705 - Registrations, reports, and applications for approval.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... approval. 107.705 Section 107.705 Transportation Other Regulations Relating to Transportation PIPELINE AND... Hazardous Materials Safety (Attention: Approvals, PHH-32), Pipeline and Hazardous Materials Safety... the applicant, will issue a written extension to permit operation under the terms of the...

  10. PRN Notice 94-4: Interim Measures for the Registration of Antimicrobial Products/Liquid Chemical Germicides with Medical Device Use Claims Under the Memorandum of Understanding Between EPA and FDA

    EPA Pesticide Factsheets

    This Notice is intended to provide the regulated community with detailed guidance on the interim EPA registration procedures for antimicrobial products affected by the June 4, 1993, Memorandum of Understanding (MOU) between EPA and FDA.

  11. Earth Science Imagery Registration

    NASA Technical Reports Server (NTRS)

    LeMoigne, Jacqueline; Morisette, Jeffrey; Cole-Rhodes, Arlene; Johnson, Kisha; Netanyahu, Nathan S.; Eastman, Roger; Stone, Harold; Zavorin, Ilya

    2003-01-01

    The study of global environmental changes involves the comparison, fusion, and integration of multiple types of remotely-sensed data at various temporal, radiometric, and spatial resolutions. Results of this integration may be utilized for global change analysis, as well as for the validation of new instruments or for new data analysis. Furthermore, future multiple satellite missions will include many different sensors carried on separate platforms, and the amount of remote sensing data to be combined is increasing tremendously. For all of these applications, the first required step is fast and automatic image registration, and as this need for automating registration techniques is being recognized, it becomes necessary to survey all the registration methods which may be applicable to Earth and space science problems and to evaluate their performances on a large variety of existing remote sensing data as well as on simulated data of soon-to-be-flown instruments. In this paper we present one of the first steps toward such an exhaustive quantitative evaluation. First, the different components of image registration algorithms are reviewed, and different choices for each of these components are described. Then, the results of the evaluation of the corresponding algorithms combining these components are presented o n several datasets. The algorithms are based on gray levels or wavelet features and compute rigid transformations (including scale, rotation, and shifts). Test datasets include synthetic data as well as data acquired over several EOS Land Validation Core Sites with the IKONOS and the Landsat-7 sensors.

  12. A gaseous radiochemical method for registration of ionizing radiation and its possible applications in science and economy

    NASA Astrophysics Data System (ADS)

    Lebedev, S. G.; Akulinichev, S. V.; Iljinov, A. S.; Yants, V. E.

    2006-05-01

    This work presents a new possibility of registration of ionizing radiation by the flowing gaseous radiochemical method (FGRM). The specified method uses the property of some solid crystalline lattice materials for a free emission of radioactive isotopes of inert gas atoms formed as a result of nuclear reactions. Generated in an ampoule of the detector, the radioactive inert gases are transported by a gas-carrier into the proportional gas counter of the flowing type, where the decay rate of the radioactive gas species is measured. This quantity is unequivocally related to the flux of particles (neutrons, protons, light and heavy ions) at the location of the ampoule. The method was used to monitor the neutron flux of the pulsed neutron target “RADEX” driven by the linear proton accelerator of INR RAS. Further progress of the FGRM may give rise to possible applications in nuclear physics, astrophysics and medicine, in the nondestructive control of fissionable materials, diagnostics of thermonuclear plasma, monitoring of fluxes and measurement of spectra of bombarding particles.

  13. [Hygiene and standards aspects of registration, marking and labeling of food products prepared from genetically modified sources].

    PubMed

    Onishchenko, G G

    2001-01-01

    The basic requirements to problems of registration, marking and labelling of the foodstuff prepared from generically modified sources are stated. The comparative analysis of the above-named problems in the different countries (USA, countries of EU, Russia etc.) is given.

  14. Automatic registration of satellite imagery

    NASA Technical Reports Server (NTRS)

    Fonseca, Leila M. G.; Costa, Max H. M.; Manjunath, B. S.; Kenney, C.

    1997-01-01

    Image registration is one of the basic image processing operations in remote sensing. With the increase in the number of images collected every day from different sensors, automated registration of multi-sensor/multi-spectral images has become an important issue. A wide range of registration techniques has been developed for many different types of applications and data. The objective of this paper is to present an automatic registration algorithm which uses a multiresolution analysis procedure based upon the wavelet transform. The procedure is completely automatic and relies on the grey level information content of the images and their local wavelet transform modulus maxima. The registration algorithm is very simple and easy to apply because it needs basically one parameter. We have obtained very encouraging results on test data sets from the TM and SPOT sensor images of forest, urban and agricultural areas.

  15. 40 CFR 152.115 - Conditions of registration.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Section 152.115 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS PESTICIDE REGISTRATION AND CLASSIFICATION PROCEDURES Agency Review of Applications § 152.115 Conditions of... later than the time such data are required to be submitted for similar pesticide products...

  16. 40 CFR 152.115 - Conditions of registration.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Section 152.115 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS PESTICIDE REGISTRATION AND CLASSIFICATION PROCEDURES Agency Review of Applications § 152.115 Conditions of... later than the time such data are required to be submitted for similar pesticide products...

  17. 40 CFR 152.115 - Conditions of registration.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Section 152.115 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS PESTICIDE REGISTRATION AND CLASSIFICATION PROCEDURES Agency Review of Applications § 152.115 Conditions of... later than the time such data are required to be submitted for similar pesticide products...

  18. Three-dimensional elastic image registration based on strain energy minimization: application to prostate magnetic resonance imaging.

    PubMed

    Zhang, Bao; Arola, Dwayne D; Roys, Steve; Gullapalli, Rao P

    2011-08-01

    The use of magnetic resonance (MR) imaging in conjunction with an endorectal coil is currently the clinical standard for the diagnosis of prostate cancer because of the increased sensitivity and specificity of this approach. However, imaging in this manner provides images and spectra of the prostate in the deformed state because of the insertion of the endorectal coil. Such deformation may lead to uncertainties in the localization of prostate cancer during therapy. We propose a novel 3-D elastic registration procedure that is based on the minimization of a physically motivated strain energy function that requires the identification of similar features (points, curves, or surfaces) in the source and target images. The Gauss-Seidel method was used in the numerical implementation of the registration algorithm. The registration procedure was validated on synthetic digital images, MR images from prostate phantom, and MR images obtained on patients. The registration error, assessed by averaging the displacement of a fiducial landmark in the target to its corresponding point in the registered image, was 0.2 ± 0.1 pixels on synthetic images. On the prostate phantom and patient data, the registration errors were 1.0 ± 0.6 pixels (0.6 ± 0.4 mm) and 1.8 ± 0.7 pixels (1.1 ± 0.4 mm), respectively. Registration also improved image similarity (normalized cross-correlation) from 0.72 ± 0.10 to 0.96 ± 0.03 on patient data. Registration results on digital images, phantom, and prostate data in vivo demonstrate that the registration procedure can be used to significantly improve both the accuracy of localized therapies such as brachytherapy or external beam therapy and can be valuable in the longitudinal follow-up of patients after therapy.

  19. Evaluation of moving and handling training for pre-registration nurses and its application to practice.

    PubMed

    Cornish, Jocelyn; Jones, Anne

    2007-05-01

    This paper describes preliminary questionnaire survey work in a research programme exploring M&H training for student nurses (n=106) and its application to practice. The aim of the study was to provide evidence of the students' experiences of M&H in the clinical setting to inform future educational development. The students were able to distinguish between acceptable and unacceptable practice they observed. Good practice comprised planning and coordination within the nursing team and careful reassurance of the patient. Regarding poor practice, the students identified that equipment was unavailable or not used and that staff demonstrated poor posture in this work or used condemned techniques thought to be detrimental to the staff and the patients. Fewer students had observed: risk assessments, equipment safety checks and use of a hoist for lifting fallen patients, than had seen other accepted M&H procedures. Contrary to the Manual Handling Operations Regulations (HSE. 1992; 1998. Manual Handling Operations Regulations. HMSO, London.) and hospital 'no-lifting' policies, 71% of the respondents had been asked to participate in a manoeuvre that they thought was wrong and a similar number had been asked to physically lift patients without using recommended equipment. Perceived injuries to both staff and patients were also described.

  20. Applications for Dielectric Properties of Agricultural Products

    USDA-ARS?s Scientific Manuscript database

    The use of dielectric properties of agricultural products for sensing moisture in grain and seed and their application in radio-frequency and microwave dielectric heating are discussed briefly. Values for the dielectric properties of a number of products, including grain, fruit, and poultry products...