Clinical Correlates of Infarct Shape and Volume in Lacunar Strokes The SPS3 Trial

PubMed Central

Asdaghi, Negar; Pearce, Leasly A.; Nakajima, Makoto; Field, Thalia S; Bazan, Carlos; Cermeno, Franco; McClure, Leslie A.; Anderson, David C.; Hart, Robert G.; Benavente, Oscar R.

2014-01-01

Background and Purpose Infarct size and location are thought to correlate with different mechanisms of lacunar infarcts. We examined the relationship between the size and shape of lacunar infarcts and vascular risk factors and outcomes. Methods We studied 1679 participants in the Secondary Prevention of Small Subcortical Stroke trial with a lacunar infarct visualized on DWI. Infarct volume was measured planimetrically, and shape was classified based on visual analysis after 3D reconstruction of axial MRI slices. Results Infarct shape was ovoid/spheroid in 63%, slab 12%, stick 7%, and multi- component 17%. Median infarct volume was smallest in ovoid/spheroid relative to other shapes: 0.46, 0.65, 0.54, and 0.90 ml respectively, p< 0.001. Distributions of vascular risk factors were similar across the four groups except that patients in the ovoid/spheroid and stick groups were more often diabetic and those with multi-component had significantly higher blood pressure at study entry. Intracranial stenosis did not differ among groups (p=0.2). Infarct volume was not associated with vascular risk factors. Increased volume was associated with worse functional status at baseline and 3 months. Overall, 162 recurrent strokes occurred over an average of 3.4 years of follow-up with no difference in recurrent ischemic stroke rate by shape or volume. Conclusion In patients with recent lacunar stroke, vascular risk factor profile was similar amongst the different infarct shapes and sizes. Infarct size correlated with worse short- term functional outcome. Neither shape nor volume was predictive of stroke recurrence. PMID:25190442

Mathematical investigations of branch length similarity entropy profiles of shapes for various resolutions

NASA Astrophysics Data System (ADS)

Jeon, Wonju; Lee, Sang-Hee

2012-12-01

In our previous study, we defined the branch length similarity (BLS) entropy for a simple network consisting of a single node and numerous branches. As the first application of this entropy to characterize shapes, the BLS entropy profiles of 20 battle tank shapes were calculated from simple networks created by connecting pixels in the boundary of the shape. The profiles successfully characterized the tank shapes through a comparison of their BLS entropy profiles. Following the application, this entropy was used to characterize human's emotional faces, such as happiness and sad, and to measure the degree of complexity for termite tunnel networks. These applications indirectly indicate that the BLS entropy profile can be a useful tool to characterize networks and shapes. However, the ability of the BLS entropy in the characterization depends on the image resolution because the entropy is determined by the number of nodes for the boundary of a shape. Higher resolution means more nodes. If the entropy is to be widely used in the scientific community, the effect of the resolution on the entropy profile should be understood. In the present study, we mathematically investigated the BLS entropy profile of a shape with infinite resolution and numerically investigated the variation in the pattern of the entropy profile caused by changes in the resolution change in the case of finite resolution.

Brain strain uncertainty due to shape variation in and simplification of head angular velocity profiles.

PubMed

Zhao, Wei; Ji, Songbai

2017-04-01

Head angular velocity, instead of acceleration, is more predictive of brain strains. Surprisingly, no study exists that investigates how shape variation in angular velocity profiles affects brain strains, beyond characteristics such as peak magnitude and impulse duration. In this study, we evaluated brain strain uncertainty due to variation in angular velocity profiles and further compared with that resulting from simplifying the profiles into idealized shapes. To do so, we used reconstructed head impacts from American National Football League for shape extraction and simulated head uniaxial coronal rotations from onset to full stop. The velocity profiles were scaled to maintain an identical peak velocity magnitude and duration in order to isolate the shape for investigation. Element-wise peak maximum principal strains from 44 selected impacts were obtained. We found that the shape of angular velocity profile could significantly affect brain strain magnitude (e.g., percentage difference of 4.29-17.89 % in the whole brain relative to the group average, with cumulative strain damage measure (CSDM) uncertainty range of 23.9 %) but not pattern (correlation coefficient of 0.94-0.99). Strain differences resulting from simplifying angular velocity profiles into idealized shapes were largely within the range due to shape variation, in both percentage difference and CSDM (signed difference of 3.91 % on average, with a typical range of 0-6 %). These findings provide important insight into the uncertainty or confidence in the performance of kinematics-based injury metrics. More importantly, they suggest the feasibility to simplify head angular velocity profiles into idealized shapes, at least within the confinements of the profiles evaluated, to enable real-time strain estimation via pre-computation in the future.

Brain strain uncertainty due to shape variation in and simplification of head angular velocity profiles

PubMed Central

Zhao, Wei; Ji, Songbai

2016-01-01

Head angular velocity, instead of acceleration, is more predictive of brain strains. Surprisingly, no study exists that investigates how shape variation in angular velocity profiles affects brain strains, beyond characteristics such as peak magnitude and impulse duration. In this study, we evaluated brain strain uncertainty due to variation in angular velocity profiles, and further compared with that resulting from simplifying the profiles into idealized shapes. To do so, we used reconstructed head impacts from American National Football League for shape extraction, and simulated head uniaxial coronal rotations from onset to full stop. The velocity profiles were scaled to maintain an identical peak velocity magnitude and duration in order to isolate the shape for investigation. Element-wise peak maximum principal strains from 44 selected impacts were obtained. We found that the shape of angular velocity profile could significantly affect brain strain magnitude (e.g., percentage difference of 4.29–17.89% in the whole-brain relative to the group average, with cumulative strain damage measure (CSDM) uncertainty range of 23.9%) but not pattern (correlation coefficient of 0.94–0.99). Strain differences resulting from simplifying angular velocity profiles into idealized shapes were largely within the range due to shape variation, in both percentage difference and CSDM (signed difference of 3.91% on average, with a typical range of 0–6%). These findings provide important insight into the uncertainty or confidence in the performance of kinematics-based injury metrics. More importantly, they suggest the feasibility to simplify head angular velocity profiles into idealized shapes, at least within the confinements of the profiles evaluated, to enable real-time strain estimation via pre-computation in the future. PMID:27644441

Relating shape/weight based self-esteem, depression, and anxiety with weight and perceived physical health among young adults.

PubMed

Kamody, Rebecca C; Thurston, Idia B; Decker, Kristina M; Kaufman, Caroline C; Sonneville, Kendrin R; Richmond, Tracy K

2018-06-01

Simultaneous contributions of self-esteem, depression, and anxiety to weight and perceived physical health in young adults is understudied. A diverse sample of 424 young adults completed measures of shape/weight based self-esteem, depression, anxiety, and perceived physical health. Height and weight were measured to calculate body mass index (BMI). Latent profile analysis was conducted to derive patterns of depression, anxiety, and shape/weight based self-esteem. Then, we examined the association of the profiles with weight status and perceived physical health. Three profiles emerged: (1) High Shape/Weight Influence (HSWI); (2) Low Shape/Weight, Depression, & Anxiety Influence (LSWDAI); and (3) High Depression & Anxiety Influence (HDAI). The HSWI profile had significantly higher BMI than the LSWDAI and HDAI profiles, and significantly lower perceived physical health than the LSWDAI profile. Over emphasis on shape/weight, regardless of depression and anxiety, is associated with elevated weight and negative internalized health views. Copyright © 2018 Elsevier Ltd. All rights reserved.

Dependence of recycling and edge profiles on lithium evaporation in high triangularity, high performance NSTX H-mode discharges.

DOE PAGES

Maingi, R.; Osborne, T. H.; Bell, M. G.; ...

2014-11-04

In this paper, the effects of a pre-discharge lithium evaporation variation on highly shaped discharges in the National Spherical Torus Experiment (NSTX) are documented. Lithium wall conditioning (‘dose’) was routinely applied onto graphite plasma facing components between discharges in NSTX, partly to reduce recycling. Reduced D α emission from the lower and upper divertor and center stack was observed, as well as reduced midplane neutral pressure; the magnitude of reduction increased with the pre-discharge lithium dose. Improved energy confinement, both raw τ E and H-factor normalized to scalings, with increasing lithium dose was also observed. At the highest doses, wemore » also observed elimination of edge-localized modes. The midplane edge plasma profiles were dramatically altered, comparable to lithium dose scans at lower shaping, where the strike point was farther from the lithium deposition centroid. As a result, this indicates that the benefits of lithium conditioning should apply to the highly shaped plasmas planned in NSTX-U.« less

Profile shape optimization in multi-jet impingement cooling of dimpled topologies for local heat transfer enhancement

NASA Astrophysics Data System (ADS)

Negi, Deepchand Singh; Pattamatta, Arvind

2015-04-01

The present study deals with shape optimization of dimples on the target surface in multi-jet impingement heat transfer. Bezier polynomial formulation is incorporated to generate profile shapes for the dimple profile generation and a multi-objective optimization is performed. The optimized dimple shape exhibits higher local Nusselt number values compared to the reference hemispherical dimpled plate optimized shape which can be used to alleviate local temperature hot spots on target surface.

Transition Experiences of Disabled Young People

ERIC Educational Resources Information Center

Piggott, Linda; Houghton, Ann-Marie

2007-01-01

This paper outlines the changing employment climate and shift in attitudes towards disabled people who are expected to become economically active in order to fulfill their role as responsible citizens. We briefly describe the employment profile of disabled people and reiterate the combination of factors identified in shaping progression into the…

Behavioural profiles are shaped by social experience: when, how and why.

PubMed

Sachser, Norbert; Kaiser, Sylvia; Hennessy, Michael B

2013-05-19

The comprehensive understanding of individual variation in behavioural profiles is a current and timely topic not only in behavioural ecology, but also in biopsychological and biomedical research. This study focuses on the shaping of behavioural profiles by the social environment in mammals. We review evidence that the shaping of behavioural profiles occurs from the prenatal phase through adolescence and beyond. We focus specifically on adolescence, a sensitive phase during which environmental stimuli have distinctive effects on the modulation of behavioural profiles. We discuss causation, in particular, how behavioural profiles are shaped by social stimuli through behavioural and neuroendocrine processes. We postulate a central role for maternal hormones during the prenatal phase, for maternal behaviour during lactation and for the interaction of testosterone and stress hormones during adolescence. We refer to evolutionary history and attempt to place developmental shaping into broader evolutionary historical trends. Finally, we address survival value. We argue that the shaping of behavioural profiles by environmental stimuli from the prenatal phase through adolescence represents an effective mechanism for repeated and rapid adaptation during the lifetime. Notably, the adolescent phase may provide a last chance for correction if the future environment deviates from that predicted in earlier phases.

Behavioural profiles are shaped by social experience: when, how and why

PubMed Central

Sachser, Norbert; Kaiser, Sylvia; Hennessy, Michael B.

2013-01-01

The comprehensive understanding of individual variation in behavioural profiles is a current and timely topic not only in behavioural ecology, but also in biopsychological and biomedical research. This study focuses on the shaping of behavioural profiles by the social environment in mammals. We review evidence that the shaping of behavioural profiles occurs from the prenatal phase through adolescence and beyond. We focus specifically on adolescence, a sensitive phase during which environmental stimuli have distinctive effects on the modulation of behavioural profiles. We discuss causation, in particular, how behavioural profiles are shaped by social stimuli through behavioural and neuroendocrine processes. We postulate a central role for maternal hormones during the prenatal phase, for maternal behaviour during lactation and for the interaction of testosterone and stress hormones during adolescence. We refer to evolutionary history and attempt to place developmental shaping into broader evolutionary historical trends. Finally, we address survival value. We argue that the shaping of behavioural profiles by environmental stimuli from the prenatal phase through adolescence represents an effective mechanism for repeated and rapid adaptation during the lifetime. Notably, the adolescent phase may provide a last chance for correction if the future environment deviates from that predicted in earlier phases. PMID:23569292

Comparison of tropospheric NO2 from in situ aircraft measurements with near-real-time and standard product data from OMI

NASA Astrophysics Data System (ADS)

Bucsela, E. J.; Perring, A. E.; Cohen, R. C.; Boersma, K. F.; Celarier, E. A.; Gleason, J. F.; Wenig, M. O.; Bertram, T. H.; Wooldridge, P. J.; Dirksen, R.; Veefkind, J. P.

2008-08-01

We present an analysis of in situ NO2 measurements from aircraft experiments between summer 2004 and spring 2006. The data are from the INTEX-A, PAVE, and INTEX-B campaigns and constitute the most comprehensive set of tropospheric NO2 profiles to date. Profile shapes from INTEX-A and PAVE are found to be qualitatively similar to annual mean profiles from the GEOS-Chem model. Using profiles from the INTEX-B campaign, we perform error-weighted linear regressions to compare the Ozone Monitoring Instrument (OMI) tropospheric NO2 columns from the near-real-time product (NRT) and standard product (SP) with the integrated in situ columns. Results indicate that the OMI SP algorithm yields NO2 amounts lower than the in situ columns by a factor of 0.86 (±0.2) and that NO2 amounts from the NRT algorithm are higher than the in situ data by a factor of 1.68 (±0.6). The correlation between the satellite and in situ data is good (r = 0.83) for both algorithms. Using averaging kernels, the influence of the algorithm's a priori profiles on the satellite retrieval is explored. Results imply that air mass factors from the a priori profiles are on average slightly larger (˜10%) than those from the measured profiles, but the differences are not significant.

Technology optimization techniques for multicomponent optical band-pass filter manufacturing

NASA Astrophysics Data System (ADS)

Baranov, Yuri P.; Gryaznov, Georgiy M.; Rodionov, Andrey Y.; Obrezkov, Andrey V.; Medvedev, Roman V.; Chivanov, Alexey N.

2016-04-01

Narrowband optical devices (like IR-sensing devices, celestial navigation systems, solar-blind UV-systems and many others) are one of the most fast-growing areas in optical manufacturing. However, signal strength in this type of applications is quite low and performance of devices depends on attenuation level of wavelengths out of operating range. Modern detectors (photodiodes, matrix detectors, photomultiplier tubes and others) usually do not have required selectivity or have higher sensitivity to background spectrum at worst. Manufacturing of a single component band-pass filter with high attenuation level of wavelength is resource-intensive task. Sometimes it's not possible to find solution for this problem using existing technologies. Different types of filters have technology variations of transmittance profile shape due to various production factors. At the same time there are multiple tasks with strict requirements for background spectrum attenuation in narrowband optical devices. For example, in solar-blind UV-system wavelengths above 290-300 nm must be attenuated by 180dB. In this paper techniques of multi-component optical band-pass filters assembly from multiple single elements with technology variations of transmittance profile shape for optimal signal-tonoise ratio (SNR) were proposed. Relationships between signal-to-noise ratio and different characteristics of transmittance profile shape were shown. Obtained practical results were in rather good agreement with our calculations.

Observation of oscillatory radiation induced segregation profiles at grain boundaries in neutron irradiated 316 stainless steel using atom probe tomography

NASA Astrophysics Data System (ADS)

Barr, Christopher M.; Felfer, Peter J.; Cole, James I.; Taheri, Mitra L.

2018-06-01

Radiation induced segregation in austenitic Fe-Ni-Cr stainless steels is a key detrimental microstructural modification experienced in the current generation of light water reactors. In particular, Cr depletion at grain boundaries can be a significant factor in irradiation-assisted stress corrosion cracking. Therefore, having a complete knowledge and mechanistic understanding of radiation induced segregation at high dose and after a long thermal history is desired for continued sustainability of existing reactors. Here, we examine a 12% cold worked AISI 316 stainless steel hexagonal duct exposed in the lower dose, outer blanket region of the EBR-II reactor, by using advanced characterization and analysis techniques including atom probe tomography and analytical scanning transmission electron microscopy. Contrary to existing literature, we observe an oscillatory w-shape Cr and M-shape Ni concentration profile at 31 dpa. The presence and characterization through advanced atom probe tomography analysis of the w-shape Cr RIS profile is discussed in the context of the localized GB plane interfacial excess of the other major and minor alloying elements. The key finding of a co-segregation phenomena coupling Cr, Mo, and C is discussed in the context of the existing solute segregation literature under irradiation with emphasis on improved spatial and chemical resolution of atom probe tomography.

Review of Graduate Research on Language Assessment in Turkey between 2011 and 2016

ERIC Educational Resources Information Center

Uzun, Aysenur; Kilickaya, Ferit

2017-01-01

Language assessment is one of the key factors affecting language learning contexts since it not only provides information about the learners and teachers' performance in the classroom but also shapes how languages are learned and practiced depending on how assessment is conducted. Technology, different learner profiles, problems with the existing…

Return to Work and Social Communication Ability Following Severe Traumatic Brain Injury

ERIC Educational Resources Information Center

Douglas, Jacinta M.; Bracy, Christine A.; Snow, Pamela C.

2016-01-01

Purpose: Return to competitive employment presents a major challenge to adults who survive traumatic brain injury (TBI). This study was undertaken to better understand factors that shape employment outcome by comparing the communication profiles and self-awareness of communication deficits of adults who return to and maintain employment with those…

Suppression of MHD fluctuations leading to improved confinement in a gun-driven spheromak.

PubMed

McLean, H S; Woodruff, S; Hooper, E B; Bulmer, R H; Hill, D N; Holcomb, C; Moller, J; Stallard, B W; Wood, R D; Wang, Z

2002-03-25

Magnetic fluctuations have been reduced to approximately 1% during discharges on the Sustained Spheromak Physics Experiment by shaping the spatial distribution of the bias magnetic flux in the device. In the resulting quiescent regime, the safety factor profile is nearly flat in the plasma and the dominant ideal and resistive MHD modes are greatly reduced. During this period, the temperature profile is peaked at the magnetic axis and maps onto magnetic flux contours. Energy confinement time is improved over previous reports in a driven spheromak.

Central safety factor and β N control on NSTX-U via beam power and plasma boundary shape modification, using TRANSP for closed loop simulations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Boyer, M. D.; Andre, R.; Gates, D. A.

The high-performance operational goals of NSTX-U will require development of advanced feedback control algorithms, including control of ßN and the safety factor profile. In this work, a novel approach to simultaneously controlling ßN and the value of the safety factor on the magnetic axis, q0, through manipulation of the plasma boundary shape and total beam power, is proposed. Simulations of the proposed scheme show promising results and motivate future experimental implementation and eventual integration into a more complex current profile control scheme planned to include actuation of individual beam powers, density, and loop voltage. As part of this work, amore » flexible framework for closed loop simulations within the high-fidelity code TRANSP was developed. The framework, used here to identify control-design-oriented models and to tune and test the proposed controller, exploits many of the predictive capabilities of TRANSP and provides a means for performing control calculations based on user-supplied data (controller matrices, target waveforms, etc.). The flexible framework should enable high-fidelity testing of a variety of control algorithms, thereby reducing the amount of expensive experimental time needed to implement new control algorithms on NSTX-U and other devices.« less

Central safety factor and βN control on NSTX-U via beam power and plasma boundary shape modification, using TRANSP for closed loop simulations

NASA Astrophysics Data System (ADS)

Boyer, M. D.; Andre, R.; Gates, D. A.; Gerhardt, S.; Goumiri, I. R.; Menard, J.

2015-05-01

The high-performance operational goals of NSTX-U will require development of advanced feedback control algorithms, including control of βN and the safety factor profile. In this work, a novel approach to simultaneously controlling βN and the value of the safety factor on the magnetic axis, q0, through manipulation of the plasma boundary shape and total beam power, is proposed. Simulations of the proposed scheme show promising results and motivate future experimental implementation and eventual integration into a more complex current profile control scheme planned to include actuation of individual beam powers, density, and loop voltage. As part of this work, a flexible framework for closed loop simulations within the high-fidelity code TRANSP was developed. The framework, used here to identify control-design-oriented models and to tune and test the proposed controller, exploits many of the predictive capabilities of TRANSP and provides a means for performing control calculations based on user-supplied data (controller matrices, target waveforms, etc). The flexible framework should enable high-fidelity testing of a variety of control algorithms, thereby reducing the amount of expensive experimental time needed to implement new control algorithms on NSTX-U and other devices.

Size and shape-dependent cytotoxicity profile of gold nanoparticles for biomedical applications.

PubMed

Woźniak, Anna; Malankowska, Anna; Nowaczyk, Grzegorz; Grześkowiak, Bartosz F; Tuśnio, Karol; Słomski, Ryszard; Zaleska-Medynska, Adriana; Jurga, Stefan

2017-06-01

Metallic nanoparticles, in particular gold nanoparticles (AuNPs), offer a wide spectrum of applications in biomedicine. A crucial issue is their cytotoxicity, which depends greatly on various factors, including morphology of nanoparticles. Because metallic nanoparticles have an effect on cell membrane integrity, their shape and size may affect the viability of cells, due to their different geometries as well as physical and chemical interactions with cell membranes. Variations in the size and shape of gold nanoparticles may indicate particular nanoparticle morphologies that provide strong cytotoxicity effects. Synthesis of different sized and shaped bare AuNPs was performed with spherical (~ 10 nm), nanoflowers (~ 370 nm), nanorods (~ 41 nm), nanoprisms (~ 160 nm) and nanostars (~ 240 nm) morphologies. These nanostructures were characterized and interacting with cancer (HeLa) and normal (HEK293T) cell lines and cell viability tests were performed by WST-1 tests and fluorescent live/dead cell imaging experiments. It was shown that various shapes and sizes of gold nanostructures may affect the viability of the cells. Gold nanospheres and nanorods proved to be more toxic than star, flower and prism gold nanostructures. This may be attributed to their small size and aggregation process. This is the first report concerning a comparison of cytotoxic profile in vitro with a wide spectrum of bare AuNPs morphology. The findings show their possible use in biomedical applications.

Species Profiles. Life Histories and Environmental Requirements of Coastal Fishes and Invertebrates (Gulf of Mexico). American Oyster.

DTIC Science & Technology

1986-07-01

valves when fully oyster (Butler 1954). Its range closed. extends to the Yucatan Peninsula of Mexico and to Venezuela. Along the Shel. shape is... nutritional factors which affect report on the 1950 opening. Pubi. the growth and setting of the Inst. Mar. Sci. Univ. Texas. larvae of the oyster

Tuning donut profile for spatial resolution in stimulated emission depletion microscopy.

PubMed

Neupane, Bhanu; Chen, Fang; Sun, Wei; Chiu, Daniel T; Wang, Gufeng

2013-04-01

In stimulated emission depletion (STED)-based or up-conversion depletion-based super-resolution optical microscopy, the donut-shaped depletion beam profile is of critical importance to its resolution. In this study, we investigate the transformation of the donut-shaped depletion beam focused by a high numerical aperture (NA) microscope objective, and model STED point spread function (PSF) as a function of donut beam profile. We show experimentally that the intensity profile of the dark kernel of the donut can be approximated as a parabolic function, whose slope is determined by the donut beam size before the objective back aperture, or the effective NA. Based on this, we derive the mathematical expression for continuous wave (CW) STED PSF as a function of focal plane donut and excitation beam profiles, as well as dye properties. We find that the effective NA and the residual intensity at the center are critical factors for STED imaging quality and the resolution. The effective NA is critical for STED resolution in that it not only determines the donut shape but also the area the depletion laser power is dispersed. An improperly expanded depletion beam will have negligible improvement in resolution. The polarization of the depletion beam also plays an important role as it affects the residual intensity in the center of the donut. Finally, we construct a CW STED microscope operating at 488 nm excitation and 592 nm depletion with a resolution of 70 nm. Our study provides detailed insight to the property of donut beam, and parameters that are important for the optimal performance of STED microscopes. This paper will provide a useful guide for the construction and future development of STED microscopes.

Evaluation of the in-service safety performance of safety-shape and vertical concrete barriers.

DOT National Transportation Integrated Search

2011-12-16

Roadside concrete barriers have been widely used to protect errant motorists from hitting : roadside hazards or obstacles. Two concrete barrier profiles, vertical and safety-shape, have been used : for this purpose. The safety-shape profile has been ...

On Study of Air/Space-borne Dual-Wavelength Radar for Estimates of Rain Profiles

NASA Technical Reports Server (NTRS)

Liao, Liang; Meneghini, Robert

2004-01-01

In this study, a framework is discussed to apply air/space-borne dual-wavelength radar for the estimation of characteristic parameters of hydrometeors. The focus of our study is on the Global Precipitation Measurements (GPM) precipitation radar, a dual-wavelength radar that operates at Ku (13.8 GHz) and Ka (35 GHz) bands. As the droplet size distributions (DSD) of rain are expressed as the Gamma function, a procedure is described to derive the median volume diameter (D(sub 0)) and particle number concentration (N(sub T)) of rain. The correspondences of an important quantity of dual-wavelength radar, defined as deferential frequency ratio (DFR), to the D(sub 0) in the melting region are given as a function of the distance from the 0 C isotherm. A self-consistent iterative algorithm that shows a promising to account for rain attenuation of radar and infer the DSD without use of surface reference technique (SRT) is examined by applying it to the apparent radar reflectivity profiles simulated from the DSD model and then comparing the estimates with the model (true) results. For light to moderate rain the self-consistent rain profiling approach converges to unique and correct solutions only if the same shape factors of Gamma functions are used both to generate and retrieve the rain profiles, but does not converges to the true solutions if the DSD form is not chosen correctly. To further examine the dual-wavelength techniques, the self-consistent algorithm, along with forward and backward rain profiling algorithms, is then applied to the measurements taken from the 2nd generation Precipitation Radar (PR-2) built by Jet Propulsion Laboratory. It is found that rain profiles estimated from the forward and backward approaches are not sensitive to shape factor of DSD Gamma distribution, but the self-consistent method is.

LETTER: Test of Te profile invariance by sensitivity studies

NASA Astrophysics Data System (ADS)

Becker, G.

1992-06-01

The response of the electron temperature profile shape to variations of the electron heating and density profiles is investigated in different confinement regimes. It is shown that the changes in rTe = -Te/(dTe/dr) exceed the measurement error if the shape of the electron heat diffusivity χe(r) is kept fixed. The observed constancy of rTe(r) in the outer half of the plasma is incompatible with such a fixed χe(r) shape, i.e., a Te profile constraining mechanism must be present. Local transport laws of the form χe varies as rTe-α with α gtrsim 4 and χe propto (dTe/dr)α with α >= 2 yield the experimental stiffness of the Te(r) shape but conflict with empirical χe scalings. These results support the model of a self-organizing and adjusting χe(r) causing Te profile invariance

Predicting ozone profile shape from satellite UV spectra

NASA Astrophysics Data System (ADS)

Xu, Jian; Loyola, Diego; Romahn, Fabian; Doicu, Adrian

2017-04-01

Identifying ozone profile shape is a critical yet challenging job for the accurate reconstruction of vertical distributions of atmospheric ozone that is relevant to climate change and air quality. Motivated by the need to develop an approach to reliably and efficiently estimate vertical information of ozone and inspired by the success of machine learning techniques, this work proposes a new algorithm for deriving ozone profile shapes from ultraviolet (UV) absorption spectra that are recorded by satellite instruments, e.g. GOME series and the future Sentinel missions. The proposed algorithm formulates this particular inverse problem in a classification framework rather than a conventional inversion one and places an emphasis on effectively characterizing various profile shapes based on machine learning techniques. Furthermore, a comparison of the ozone profiles from real GOME-2 data estimated by our algorithm and the classical retrieval algorithm (Optimal Estimation Method) is performed.

Surface-brightness profiles of dwarf galaxies in the NGC 5044 Group: Implications for the luminosity-shape and scalelength-shape relationships as distance indicators

NASA Astrophysics Data System (ADS)

Young, C. K.; Currie, M. J.

2001-04-01

In a recent paper, which presents CCD photometry for fifteen dwarf and intermediate early-type galaxies in the NGC 5044 Group, it has been claimed that ``a few relatively bright galaxies with ``convex'' profiles destroy the known relation between total magnitude and the ``shape'' parameter... thus ruling out the use of this relation as a distance indicator for individual galaxies''. In the same paper, further reasons were cited supposedly ``limiting also its use as a distance indicator for groups of galaxies''. We demonstrate that none of the three relatively bright galaxies cited as possessing ``convex'' profiles actually has a convex profile, and that one of these objects should be excluded because it is a late-type galaxy. Of the two remaining objects, one has an anomalous profile shape whilst the other is brighter than one might expect from its colour alone. However, we show that all of the other issues raised have already been accounted for by Young & Currie (\\cite{you94}, \\cite{you95} & \\cite{you98}). The main implications of the new observations are: (1) that the case of one galaxy with an anomalous profile shape, N42, highlights the need for some a priori criteria to be defined in order to establish objectively which objects are not suitable for distance determinations; and (2) on the basis of another unusual galaxy, N50, colour has now been shown to be a poorer discriminant between objects of the same profile shape and scalelength (but of different central surface brightness) than previously thought. How significant this latter problem is depends on how common N50-like objects are. This consideration reinforces the case for always using the more general scalelength-shape relationship of Young & Currie (\\cite{you95}) in preference to the luminosity-shape one of Young & Currie (\\cite{you94}). Reassuringly, through a re-analysis of the same CCD photometry, we find that NGC 5044 Group galaxies observe a tight scalelength-shape relationship. This finding supports the view that the scalelength-shape relationship is a viable distance indicator.

MO-FG-CAMPUS-IeP2-01: Characterization of Beam Shaping Filters and Photon Spectra From HVL Profiles in CT

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bujila, R; Royal Institute of Technology, Stockholm; Kull, L

Purpose: Advanced dosimetry in CT (e.g. the Monte Carlo method) requires an accurate characterization of the shaped filter and radiation quality used during a scan. The purpose of this work was to develop a method where half value layer (HVL) profiles along shaped filters could be made. From the HVL profiles the beam shaping properties and effective photon spectrum for a particular scan can be inferred. Methods: A measurement rig was developed to allow determinations of the HVL under a scatter-free narrow-beam geometry and constant focal spot to ionization chamber distance for different fan angles. For each fan angle themore » HVL is obtained by fitting the transmission of radiation through different thicknesses of an Al absorber (type 1100) using an appropriate model. The effective Al thickness of shaped filters and effective photon spectra are estimated using a model of photon emission from a Tungsten anode. This method is used to obtain the effective photon spectra and effective Al thickness of shaped filters for a CT scanner recently introduced to the market. Results: This study resulted in a set of effective photon spectra (central ray) for each kVp along with effective Al thicknesses of the different shaped filters. The effective photon spectra and effective Al thicknesses of shaped filters were used to obtain numerically approximated HVL profiles and compared to measured HVL profiles (mean absolute percentage error = 0.02). The central axis HVL found in the vendor’s technical documentation were compared to approximated HVL values (mean absolute percentage error = 0.03). Conclusion: This work has resulted in a unique method of measuring HVL profiles along shaped filters in CT. Further the effective photon spectra and the effective Al thicknesses of shaped filters that were obtained can be incorporated into Monte Carlo simulations.« less

Application of the Hartmann-Tran profile to analysis of H2O spectra

NASA Astrophysics Data System (ADS)

Lisak, D.; Cygan, A.; Bermejo, D.; Domenech, J. L.; Hodges, J. T.; Tran, H.

2015-10-01

The Hartmann-Tran profile (HTP), which has been recently recommended as a new standard in spectroscopic databases, is used to analyze spectra of several lines of H2O diluted in N2, SF6, and in pure H2O. This profile accounts for various mechanisms affecting the line-shape and can be easily computed in terms of combinations of the complex Voigt profile. A multi-spectrum fitting procedure is implemented to simultaneously analyze spectra of H2O transitions acquired at different pressures. Multi-spectrum fitting of the HTP to a theoretical model confirms that this profile provides an accurate description of H2O line-shapes in terms of residuals and accuracy of fitted parameters. This profile and its limiting cases are also fit to measured spectra for three H2O lines in different vibrational bands. The results show that it is possible to obtain accurate HTP line-shape parameters when measured spectra have a sufficiently high signal-to-noise ratio and span a broad range of collisional-to-Doppler line widths. Systematic errors in the line area and differences in retrieved line-shape parameters caused by the overly simplistic line-shape models are quantified. Also limitations of the quadratic speed-dependence model used in the HTP are demonstrated in the case of an SF6 broadened H2O line, which leads to a strongly asymmetric line-shape.

SU-F-T-577: Comparison of Small Field Dosimetry Measurements in Fields Shaped with Conical Applicators On Two Different Accelerating Systems

DOE Office of Scientific and Technical Information (OSTI.GOV)

Muir, B; McEwen, M; Belec, J

2016-06-15

Purpose: To investigate small field dosimetry measurements and associated uncertainties when conical applicators are used to shape treatment fields from two different accelerating systems. Methods: Output factor measurements are made in water in beams from the CyberKnife radiosurgery system, which uses conical applicators to shape fields from a (flattening filter-free) 6 MV beam, and in a 6 MV beam from the Elekta Precise linear accelerator (with flattening filter) with BrainLab external conical applicators fitted to shape the field. The measurements use various detectors: (i) an Exradin A16 ion chamber, (ii) two Exradin W1 plastic scintillation detectors, (iii) a Sun Nuclearmore » Edge diode, and (iv) two PTW microDiamond synthetic diamond detectors. Profiles are used for accurate detector positioning and to specify field size (FWHM). Output factor measurements are corrected with detector specific correction factors taken from the literature where available and/or from Monte Carlo simulations using the EGSnrc code system. Results: Differences in measurements of up to 1.7% are observed with a given detector type in the same beam (i.e., intra-detector variability). Corrected results from different detectors in the same beam (inter-detector differences) show deviations up to 3 %. Combining data for all detectors and comparing results from the two accelerators results in a 5.9% maximum difference for the smallest field sizes (FWHM=5.2–5.6 mm), well outside the combined uncertainties (∼1% for the smallest beams) and/or differences among detectors. This suggests that the FWHM of a measured profile is not a good specifier to compare results from different small fields with the same nominal energy. Conclusion: Large differences in results for both intra-detector variability and inter-detector differences suggest potentially high uncertainties in detector-specific correction factors. Differences between the results measured in circular fields from different accelerating systems provide insight into sources of variability in small field dosimetric measurements reported in the literature.« less

The shape parameter and its modification for defining coastal profiles

NASA Astrophysics Data System (ADS)

Türker, Umut; Kabdaşli, M. Sedat

2009-03-01

The shape parameter is important for the theoretical description of the sandy coastal profiles. This parameter has previously been defined as a function of the sediment-settling velocity. However, the settling velocity cannot be characterized over a wide range of sediment grains. This, in turn, limits the calculation of the shape parameter over a wide range. This paper provides a simpler and faster analytical equation to describe the shape parameter. The validity of the equation has been tested and compared with the previously estimated values given in both graphical and tabular forms. The results of this study indicate that the analytical solutions of the shape parameter improved the usability of profile better than graphical solutions, predicting better results both at the surf zone and offshore.

Precision Control of the Electron Longitudinal Bunch Shape Using an Emittance-Exchange Beam Line

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ha, Gwanghui; Cho, Moo -Hyun; Namkung, W.

2017-03-09

Here, we report on the experimental generation of relativistic electron bunches with a tunable longitudinal bunch shape. A longitudinal bunch-shaping (LBS) beam line, consisting of a transverse mask followed by a transverse-to-longitudinal emittance exchange (EEX) beam line, is used to tailor the longitudinal bunch shape (or current profile) of the electron bunch. The mask shapes the bunch’s horizontal profile, and the EEX beam line converts it to a corresponding longitudinal profile. The Argonne wakefield accelerator rf photoinjector delivers electron bunches into a LBS beam line to generate a variety of longitudinal bunch shapes. The quality of the longitudinal bunch shapemore » is limited by various perturbations in the exchange process. We develop a simple method, based on the incident slope of the bunch, to significantly suppress the perturbations.« less

Familiar shapes attract attention in figure-ground displays.

PubMed

Nelson, Rolf A; Palmer, Stephen E

2007-04-01

We report five experiments that explore the effect of figure-ground factors on attention. We hypothesized that figural cues, such as familiar shape, would draw attention to the figural side in an attentional cuing task using bipartite figure-ground displays. The first two experiments used faces in profile as the familiar shape and found a perceptual advantage for targets presented on the meaningful side of the central contour in detection speed (Experiment 1) and discrimination accuracy (Experiment 2). The third experiment demonstrated the figural advantage in response time (RT) with nine other familiar shapes (including a sea horse, a guitar, a fir tree, etc.), but only when targets appeared in close proximity to the contour. A fourth experiment obtained a figural advantage in a discrimination task with the larger set of familiar shapes. The final experiment ruled out eye movements as a possible confounding factor by replicating the RT advantage for targets on the figural side of face displays when all trials containing eye movements were eliminated. The results are discussed in terms of ecological influences on attention, and are cast within the framework of Yantis and Jonides's hypothesis that attention is exogenously drawn to the onset of new perceptual objects. We argue that the figural side constitutes an "object" whereas the ground side does not, and that figural cues such as shape familiarity are effective in determining which areas represent objects.

A static model of a Sendzimir mill for use in shape control

NASA Astrophysics Data System (ADS)

Gunawardene, G. W. D. M.

The design of shape control systems is an area of current interest in the steel industry. Shape is defined as the internal stress distribution resulting from a transverse variation in the reduction of the strip thickness. The object of shape control is to adjust the mill so that the rolled strip is free from internal stresses. Both static and dynamic models of the mill are required for the control system design.The subject of this thesis is the static model of the Sendzimir cold rolling mill, which is a 1-2-3-4 type cluster mill. The static model derived enables shape profiles to be calculated for a given set of actuator positions, and is used to generate the steady state mill gains. The method of calculation of these shape profiles is discussed. The shape profiles obtained for different mill schedules are plotted against the distance across the strip. The corresponding mill gains are calculated and these relate the shape changes to the actuator changes. These mill gains are presented in the form of a square matrix, obtained by measuring shape at eight points across the strip.

Direct measurements of safety factor profiles with motional Stark effect for KSTAR tokamak discharges with internal transport barriers

NASA Astrophysics Data System (ADS)

Ko, J.; Chung, J.

2017-06-01

The safety factor profile evolutions have been measured from the plasma discharges with the external current drive mechanism such as the multi-ion-source neutral beam injection for the Korea Superconducting Tokamak Advanced Research (KSTAR) for the first time. This measurement has been possible by the newly installed motional Stark effect (MSE) diagnostic system that utilizes the polarized Balmer-alpha emission from the energetic neutral deuterium atoms induced by the Stark effect under the Lorentz electric field. The 25-channel KSTAR MSE diagnostic is based on the conventional photoelastic modulator approach with the spatial and temporal resolutions less than 2 cm (for the most of the channels except 2 to 3 channels inside the magnetic axis) and about 10 ms, respectively. The strong Faraday rotation imposed on the optical elements in the diagnostic system is calibrated out from a separate and well-designed polarization measurement procedure using an in-vessel reference polarizer during the toroidal-field ramp-up phase before the plasma experiment starts. The combination of the non-inductive current drive during the ramp-up and shape control enables the formation of the internal transport barrier where the pitch angle profiles indicate flat or slightly hollow profiles in the safety factor.

Geomorphic effectiveness of a long profile shape and the role of inherent geological controls in the Himalayan hinterland area of the Ganga River basin, India

NASA Astrophysics Data System (ADS)

Sonam; Jain, Vikrant

2018-03-01

Long profiles of rivers provide a platform to analyse interaction between geological and geomorphic processes operating at different time scales. Identification of an appropriate model for river long profile becomes important in order to establish a quantitative relationship between the profile shape, its geomorphic effectiveness, and inherent geological characteristics. This work highlights the variability in the long profile shape of the Ganga River and its major tributaries, its impact on stream power distribution pattern, and role of the geological controls on it. Long profile shapes are represented by the sum of two exponential functions through the curve fitting method. We have shown that coefficients of river long profile equations are governed by the geological characteristics of subbasins. These equations further define the spatial distribution pattern of stream power and help to understand stream power variability in different geological terrains. Spatial distribution of stream power in different geological terrains successfully explains spatial variability in geomorphic processes within the Himalayan hinterland area. In general, the stream power peaks of larger rivers lie in the Higher Himalaya, and rivers in the eastern hinterland area are characterised by the highest magnitude of stream power.

Full area covered 3D profile measurement of special-shaped optics based on a new prototype non-contact profiler

NASA Astrophysics Data System (ADS)

Du, Hui-Lin; Zhou, Zhao-Zhong; Sun, Ze-Qing; Ju, Bing-Feng; Xu, Shaoning; Sun, Anyu

2017-06-01

A new prototype non-contact profiler based on surface tracking has been specially developed. Surface tracking is carried out by a specially designed dual stage probe system with the aid of a four-Degree Of Freedom high-precision motion platform. The dual stage probe system keeps a short-range optical probe constantly tracking the surface by a self-developed voice coil motor servo, by which a wide measuring range of up to 10 mm is realized. The system performance evaluation including resolution, repeatability, and scanning speed proved the good capability of the new prototype non-contact profiler. To realize a full area covered 3D profile measurement of special-shaped optics within one scanning procedure, a signal intensity monitor integrated in the surface tracking controller is specially developed. In the experiment, a snip-single-corner-rectangular-shaped freeform surface was successfully measured over full area by the new non-contact profiler. This work provides an effective solution for 3D profile measurement of special-shaped optical surfaces over full reflecting area. Experimental results demonstrate that the proposed measuring system is of great significance in quality evaluation of optical surfaces.

Full area covered 3D profile measurement of special-shaped optics based on a new prototype non-contact profiler.

PubMed

Du, Hui-Lin; Zhou, Zhao-Zhong; Sun, Ze-Qing; Ju, Bing-Feng; Xu, Shaoning; Sun, Anyu

2017-06-01

A new prototype non-contact profiler based on surface tracking has been specially developed. Surface tracking is carried out by a specially designed dual stage probe system with the aid of a four-Degree Of Freedom high-precision motion platform. The dual stage probe system keeps a short-range optical probe constantly tracking the surface by a self-developed voice coil motor servo, by which a wide measuring range of up to 10 mm is realized. The system performance evaluation including resolution, repeatability, and scanning speed proved the good capability of the new prototype non-contact profiler. To realize a full area covered 3D profile measurement of special-shaped optics within one scanning procedure, a signal intensity monitor integrated in the surface tracking controller is specially developed. In the experiment, a snip-single-corner-rectangular-shaped freeform surface was successfully measured over full area by the new non-contact profiler. This work provides an effective solution for 3D profile measurement of special-shaped optical surfaces over full reflecting area. Experimental results demonstrate that the proposed measuring system is of great significance in quality evaluation of optical surfaces.

New Vary-Chap Profile of the Topside Ionosphere Electron Density Distribution for use with the IRI Model and the GIRO Real-Time Data

NASA Technical Reports Server (NTRS)

Nsumei, Patrick; Reinisch, Bodo W.; Huang, Xueqin; Bilitza, Dieter

2012-01-01

A new Vary-Chap function is introduced for the empirical modeling of the electron density N(h) profile in the topside ionosphere that uses a shape function S(h) in the generalized Chapman function. The Vary-Chap profile extends the bottomside profile that is specified by the IRI model or measured by the Global Ionospheric Radio Observatory (GIRO) to the altitude of the ISIS-2 satellite. Some 80,000 topside profiles, measured by the topside sounder on the ISIS-2 satellite were analyzed, and the shape function S(h) was calculated for each profile. A parameterized function S*(h), composed of two sub-functions S1(h) and S2(h), is fitted to the measured S(h) profile using three free parameters. At altitudes just above the F2 layer peak height hmF2, the shape function S1 controls S(h), and at greater altitudes S2 controls S(h). The height of the intersection of S1 and S2 is defined as the transition height h(sub T) indicating the transition from an O(+) to an H(+)-dominated profile shape. The observed transition heights range from approx.500 km to 800 km.

Generalized Models for Rock Joint Surface Shapes

PubMed Central

Du, Shigui; Hu, Yunjin; Hu, Xiaofei

2014-01-01

Generalized models of joint surface shapes are the foundation for mechanism studies on the mechanical effects of rock joint surface shapes. Based on extensive field investigations of rock joint surface shapes, generalized models for three level shapes named macroscopic outline, surface undulating shape, and microcosmic roughness were established through statistical analyses of 20,078 rock joint surface profiles. The relative amplitude of profile curves was used as a borderline for the division of different level shapes. The study results show that the macroscopic outline has three basic features such as planar, arc-shaped, and stepped; the surface undulating shape has three basic features such as planar, undulating, and stepped; and the microcosmic roughness has two basic features such as smooth and rough. PMID:25152901

Generation of an ultra-flexible focused top-hat beam profile with aspheres

NASA Astrophysics Data System (ADS)

Möhl, A.; Wickenhagen, S.; Fuchs, U.

2017-02-01

The demand for a uniform intensity distribution in the focal region of the working beam is growing steadily, especially in the field of laser material processing. To generate such a top-hat beam profile, it was shown in the past, that the use of refractive beam shaping solutions provides very good results. In this work, existing beam shaping knowledge is combined with an intelligent modular approach to create a new beam shaping solution, that simplifies both, handling and integration into existing set-ups. Furthermore, the present system enables not just a flattop intensity distribution, but even donut shaped beam profile without adding any further components to the system. Additionally, this beam shaping system is built and successfully tested. Some results of the characterization are presented.

Quadrupolar asymmetry in shifted-stem vane-shaped-rod radio frequency quadrupole accelerator

NASA Astrophysics Data System (ADS)

Mehrotra, Nitin

2018-04-01

Quadrupolar Asymmetry (QA), which has been a rampant problem for rod-type Radio Frequency Quadrupole (RFQ) Linacs, arises due to the geometry of resonant structure. A systematic parametric simulation study has been performed to unravel their effect on Figure of Merit (FoM) quantities namely Quality Factor (Q), Shunt Impedance (Rsh) and Quadrupolar Asymmetry (QA). A novel stem and cavity shape is proposed, which caters to the profile of electromagnetic fields of the resonant structure. A design methodology is formulated, which demonstrates that Quadrupolar Asymmetry can be annihilated, and a symmetric electric field can be produced in all four quadrants of rod-type RFQ accelerator.

Serial profiles of electrostatic potential in five New Mexico thunderstorms

NASA Astrophysics Data System (ADS)

Stolzenburg, Maribeth; Marshall, Thomas C.

2008-07-01

Profiles of electric potential (V) integrated from balloon-borne electric field (E) measurements are used to investigate the electrical evolution of thunderstorms over the mountains in central New Mexico. With sequential soundings through multiple storms, the time skew associated with obtaining V from a noninstantaneous sounding is also studied. The data show that a basic V profile, with a maximum above a minimum, forms in the early stage of the storm and is maintained throughout its mature stage. Series of soundings from individual storms show only a gradual evolution in the V profile from the early through the mature stage, as the extrema descend in altitude and become shallower and vertically closer together. More evolution occurs in the late stage, when the shape of the V profile reverses to have a minimum above a maximum. The 17 V(z) profiles from the mature stage of five different storms are also very similar in overall shape, suggesting that the basic shape is not significantly affected by differences in lightning flash rate among these storms. The findings indicate that the potential profile during a typical sounding in the mature stage is relatively stable, and the overall shape of the mature stage V profile does not change markedly on the time scale of a particular balloon sounding (10-30 min) through New Mexico mountain storms. Thus time-skew problems in the V profiles are minor during a storm's mature stage.

The Mesozoic-Cenozoic igneous intrusions and related sediment-dominated hydrothermal activities in the South Yellow Sea Basin, the Western Pacific continental margin

NASA Astrophysics Data System (ADS)

Yumao, Pang; Xunhua, Zhang; Guolin, Xiao; Luning, Shang; Xingwei, Guo; Zhenhe, Wen

2018-04-01

Various igneous complexes were identified in multi-channel seismic reflection profiles from the South Yellow Sea Basin. It is not rare that magmatic intrusions in sedimentary basins cause strong thermal perturbations and hydrothermal activities. Some intrusion-related hydrothermal vent complexes have been identified and they are considered to originate from the deep sedimentary contact aureole around igneous intrusions and terminate in upper vents structures, and are linked by a vertical conduit system. The upper vent complexes are usually eye-shaped, dome-shaped, fault-related, crater-shaped or pock-shaped in seismic profiles. A schematic model was proposed to illustrate the structures of different types of hydrothermal vent complexes. A conceptual conduit model composed of an upper pipe-like part and a lower branching part was also derived. Hydrothermal vent complexes mainly developed during the Middle-Late Cretaceous, which is coeval with, or shortly after the intrusion. The back-arc basin evolution of the area which is related to the subduction of the Paleo-Pacific plate during the Mesozoic-Cenozoic may be the principal factor for voluminous igneous complexes and vent complexes in this area. It is significant to study the characteristics of igneous complexes and related hydrothermal vent complexes, which will have implications for the future study of this area.

Alternative Shapes and Shaping Techniques for Enhanced Transformer Ratios in Beam Driven Techniques

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lemery, F.; Piot, P.

The transformer ration of collinear beam-driven techniques can be significantly improved by shaping the current profile of the drive bunch. To date, several current shapes have been proposed to increase the transformer ratio and produce quasi-uniform energy loss within the drive bunch. Some of these tailoring techniques are possible as a results of recent beam-dynamics advances, e.g., transverse-to-longitudinal emittance exchanger. In ths paper, we propose an alternative class of longitudinal shapes that enable high transformer ratio and uniform energy loss across the drive bunch. We also suggest a simple method based on photocathode-laser shaping and passive shaping in wakefield structuremore » to realize shape close to the theoretically optimized current profiles.« less

Amplified crossflow disturbances in the laminar boundary layer on swept wings with suction

NASA Technical Reports Server (NTRS)

Dagenhart, J. R.

1981-01-01

Solution charts of the Orr-Sommerfeld equation for stationary crossflow disturbances are presented for 10 typical velocity profiles on a swept laminar flow control wing. The critical crossflow Reynolds number is shown to be a function of a boundary layer shape factor. Amplification rates for crossflow disturbances are shown to be proportional to the maximum crossflow velocity. A computer stability program called MARIA, employing the amplification rate data for the 10 crossflow velocity profiles, is constructed. This code is shown to adequately approximate more involved computer stability codes using less than two percent as much computer time while retaining the essential physical disturbance growth model.

Selective 2′-hydroxyl acylation analyzed by primer extension and mutational profiling (SHAPE-MaP) for direct, versatile, and accurate RNA structure analysis

PubMed Central

Smola, Matthew J.; Rice, Greggory M.; Busan, Steven; Siegfried, Nathan A.; Weeks, Kevin M.

2016-01-01

SHAPE chemistries exploit small electrophilic reagents that react with the 2′-hydroxyl group to interrogate RNA structure at single-nucleotide resolution. Mutational profiling (MaP) identifies modified residues based on the ability of reverse transcriptase to misread a SHAPE-modified nucleotide and then counting the resulting mutations by massively parallel sequencing. The SHAPE-MaP approach measures the structure of large and transcriptome-wide systems as accurately as for simple model RNAs. This protocol describes the experimental steps, implemented over three days, required to perform SHAPE probing and construct multiplexed SHAPE-MaP libraries suitable for deep sequencing. These steps include RNA folding and SHAPE structure probing, mutational profiling by reverse transcription, library construction, and sequencing. Automated processing of MaP sequencing data is accomplished using two software packages. ShapeMapper converts raw sequencing files into mutational profiles, creates SHAPE reactivity plots, and provides useful troubleshooting information, often within an hour. SuperFold uses these data to model RNA secondary structures, identify regions with well-defined structures, and visualize probable and alternative helices, often in under a day. We illustrate these algorithms with the E. coli thiamine pyrophosphate riboswitch, E. coli 16S rRNA, and HIV-1 genomic RNAs. SHAPE-MaP can be used to make nucleotide-resolution biophysical measurements of individual RNA motifs, rare components of complex RNA ensembles, and entire transcriptomes. The straightforward MaP strategy greatly expands the number, length, and complexity of analyzable RNA structures. PMID:26426499

SU-F-T-326: Diode Array Transmission Detector Systems Evaluation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hoffman, D; Dyer, B; Kumaran Nair, C

2016-06-15

Purpose: A new transmission detector, Delta4 Discover, developed by Scandidos (Uppsala, Sweden) was evaluated for external photon beam verification and quality assurance. The device is an array of 4040 diodes designed to be mounted on the linac accessory tray to measure photon field shape, position and fluence during patient treatment. Interfractional measurements are compared to a baseline measurement made during delivery quality assurance. The aim of this work is to evaluate the stability of the device and its effect on the shape and magnitude of the treatment beam. Methods: Beam profiles, percent depth dose, and beam attenuation was measured formore » 6, 10, and 15 MV photon beams with and without the device in place for 1×1 and 30×30 cm2 fields. Changes in profile and percent depth dose was quantified to evaluate the need to recommission the treatment beam, or account for the device with a tray factor. The stability of the radiation measurements was evaluated by measuring the deviation of each diode measurement during repeated prostate VMAT treatment delivery. Results: Photon beam profiles changed by < 1.25% in the nonpenumbra regions of the 30×30 cm2 beam. Percent depth dose curves show a 5–7% increased dose at depths < 2.5cm, but agreed within 1% at depths > 2.5cm. This indicates increased skin dose, similar to the use of a physical beam wedge. The device attenuated 6, 10, and 15 MV photon beams by 1.71±0.02%, 1.36±0.03%, and 1.17±0.03%, respectively. The diode array reproduced dosimetric measurements within 0.5% standard deviation for repeated prostate VMAT measurement. Conclusion: The device demonstrated stabile radiation measurements, while not changing the treatment beam shape in a clinically significantly manner. Use of this device can be accounted for with a tray factor, as opposed to recommissioning the treatment beam.« less

Selective 2'-hydroxyl acylation analyzed by primer extension and mutational profiling (SHAPE-MaP) for direct, versatile and accurate RNA structure analysis.

PubMed

Smola, Matthew J; Rice, Greggory M; Busan, Steven; Siegfried, Nathan A; Weeks, Kevin M

2015-11-01

Selective 2'-hydroxyl acylation analyzed by primer extension (SHAPE) chemistries exploit small electrophilic reagents that react with 2'-hydroxyl groups to interrogate RNA structure at single-nucleotide resolution. Mutational profiling (MaP) identifies modified residues by using reverse transcriptase to misread a SHAPE-modified nucleotide and then counting the resulting mutations by massively parallel sequencing. The SHAPE-MaP approach measures the structure of large and transcriptome-wide systems as accurately as can be done for simple model RNAs. This protocol describes the experimental steps, implemented over 3 d, that are required to perform SHAPE probing and to construct multiplexed SHAPE-MaP libraries suitable for deep sequencing. Automated processing of MaP sequencing data is accomplished using two software packages. ShapeMapper converts raw sequencing files into mutational profiles, creates SHAPE reactivity plots and provides useful troubleshooting information. SuperFold uses these data to model RNA secondary structures, identify regions with well-defined structures and visualize probable and alternative helices, often in under 1 d. SHAPE-MaP can be used to make nucleotide-resolution biophysical measurements of individual RNA motifs, rare components of complex RNA ensembles and entire transcriptomes.

Modular organization of the white spruce (Picea glauca) transcriptome reveals functional organization and evolutionary signatures.

PubMed

Raherison, Elie S M; Giguère, Isabelle; Caron, Sébastien; Lamara, Mebarek; MacKay, John J

2015-07-01

Transcript profiling has shown the molecular bases of several biological processes in plants but few studies have developed an understanding of overall transcriptome variation. We investigated transcriptome structure in white spruce (Picea glauca), aiming to delineate its modular organization and associated functional and evolutionary attributes. Microarray analyses were used to: identify and functionally characterize groups of co-expressed genes; investigate expressional and functional diversity of vascular tissue preferential genes which were conserved among Picea species, and identify expression networks underlying wood formation. We classified 22 857 genes as variable (79%; 22 coexpression groups) or invariant (21%) by profiling across several vegetative tissues. Modular organization and complex transcriptome restructuring among vascular tissue preferential genes was revealed by their assignment to coexpression groups with partially overlapping profiles and partially distinct functions. Integrated analyses of tissue-based and temporally variable profiles identified secondary xylem gene networks, showed their remodelling over a growing season and identified PgNAC-7 (no apical meristerm (NAM), Arabidopsis transcription activation factor (ATAF) and cup-shaped cotyledon (CUC) transcription factor 007 in Picea glauca) as a major hub gene specific to earlywood formation. Reference profiling identified comprehensive, statistically robust coexpressed groups, revealing that modular organization underpins the evolutionary conservation of the transcriptome structure. © 2015 The Authors. New Phytologist © 2015 New Phytologist Trust.

On Wind Tunnel Tests and Computations Concerning the Problem of Shrouded Propellers

NASA Technical Reports Server (NTRS)

Kruger, W.

1949-01-01

Results of measurements on a shrouded propeller are given. The propeller is designed for the high ratio of advance and high thrust loading. The effect of the shape of propeller and shroud upon the aerodynamic coefficients of the propulsion unit can be seen from the results. The highest efficiency measured is 0.71. The measurements permit the conclusion that the maximum efficiency can be essentially improved by shroud profiles of small chord and thickness. The largest static thrust factor of merit measured reaches according to Bendemann, a value of about zeta = 1.1. By the use of a nose split flap the static thrust for thin shroud profiles with small nose radius can be about doubled. In a separate section numerical investigations of the behavior of shrouded propellers for the ideal case and for the case with energy losses are carried out. The calculations are based on the assumption that the slipstream cross section depends solely on the shape of the shroud and not on the propeller loading. The reliability of this hypothesis is confirmed experimentally and by flow photographs for a shroud with small circulation. Calculation and test are also in good agreement concerning efficiency and static thrust factor of merit. The prospects of applicability for shrouded propellers and their essential advantages are discussed.

Temporal Electron-bunch Shaping from a Photoinjector for Advanced Accelerator Applications

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lemery, Francois; Piot, Philippe

2014-07-01

Advanced-accelerator applications often require the production of bunches with shaped temporal distributions. An example of sought-after shape is a linearly-ramped current profile that can be improve the transformer ratio in beam-driven acceleration, or produce energy-modulated pulse for, e.g., the subsequent generation of THz radiation. Typically,  such a shaping is achieved by manipulating ultra-relativistic electron bunches. In this contribution we discuss the possibility of shaping the bunch via photoemission and demonstrate using particle-in-cell simulations the production of MeV electron bunches with quasi-ramped current profile.

Fabrication of parabolic cylindrical microlens array by shaped femtosecond laser

NASA Astrophysics Data System (ADS)

Luo, Zhi; Yin, Kai; Dong, Xinran; Duan, Ji'an

2018-04-01

A simple and efficient technique for fabricating parabolic cylindrical microlens arrays (CMLAs) on the surface of fused silica by shaped femtosecond (fs) laser direct-writing is demonstrated. By means of spatially shaping of a Gaussian fs laser beam to a Bessel distribution, an inversed cylindrical shape laser intensity profile is formed in a specific cross-sectional plane among the shaped optical field. Applying it to experiments, large area close-packed parabolic CMLAs with line-width of 37.5 μm and array size of about 5 × 5 mm are produced. The cross-sectional outline of obtained lenslets has a satisfied parabolic profile and the numerical aperture (NA) of lenslets is more than 0.35. Furthermore, the focusing performance of the fabricated CMLA is also tested in this work and it has been demonstrated that the focusing power of the CMLA with a parabolic profile is better than that with a semi-circular one.

Integration of parts in the facial skeleton and cervical vertebrae.

PubMed

McCane, Brendan; Kean, Martin R

2011-01-01

The purpose of this study was to undertake an exploratory analysis of the relationship among parts in the facial skeleton and cervical vertebrae and their integration as 2-dimensional shapes by determining their individual variations and covariations. The study was motivated by considerations applicable to clinical orthodontics and maxillofacial surgery, in which such relationships bear directly on pretreatment analysis and assessment of posttreatment outcome. Lateral radiographs of 61 adolescents of both sexes without major malocclusions were digitized and marked up by using continuous outline spline curves for 8 defined parts in the facial skeleton, including the cervical vertebrae. Individual part variation was analyzed by using principal components analysis, and paired part covariation was analyzed by using 2-block partial least squares analysis in 2 modes: relative size, position, and shape; and shape only. For individual part variations, cranial base, soft-tissue profile, and mandible had the largest variations across the sample. For covariation of relative size, position, and shape, the cervical vertebrae were highly correlated with the cranial base (r = 0.80), nasomaxillary complex (r = 0.70), mandible (r = 0.74), maxillary dentition (r = 0.70), and mandibular dentition (r = 0.74); the maxillary dentition and mandibular dentition were highly correlated (r = 0.70); the mandible was highly correlated with the bony profile (r = 0.72), soft-tissue profile (r = 0.79), and, to a lesser extent, the cranial base (r = 0.67); the bony profile was highly correlated with the cranial base (r = 0.70) and soft-tissue profile (r = 0.80); the soft-tissue profile was highly correlated with the nasomaxillary dentition (r = 0.81). Covariation of shape only was much weaker with significant covariations found between bony profile and mandible (r = 0.53), bony profile and mandibular dentition (r = 0.65), mandibular dentition and soft-tissue profile (r = 0.54), mandibular dentition and maxillary dentition (r = 0.55), and bony profile and soft-tissue profile (r = 0.69). We found that integration of the shape of parts in the facial skeleton and cervical vertebrae is weak; it is the relative size, position, and orientation of parts that form the strongest correlations. Copyright © 2011 American Association of Orthodontists. Published by Mosby, Inc. All rights reserved.

Overview of progesterone profiles in dairy cows.

PubMed

Blavy, P; Derks, M; Martin, O; Höglund, J K; Friggens, N C

2016-09-01

The aim of this study was to gain a better understanding of the variability in shape and features of all progesterone profiles during estrus cycles in cows and to create templates for cycle shapes and features as a base for further research. Milk progesterone data from 1418 estrus cycles, coming from 1009 lactations, was obtained from the Danish Cattle Research Centre in Foulum, Denmark. Milk samples were analyzed daily using a Ridgeway ELISA-kit. Estrus cycles with less than 10 data points or shorter than 4 days were discarded, after which 1006 cycles remained in the analysis. A median kernel of three data points was used to smooth the progesterone time series. The time between start of progesterone rise and end of progesterone decline was identified by fitting a simple model consisting of base length and a quadratic curve to progesterone data, and this luteal-like phase (LLP) was used for further analysis. The data set of 1006 LLP's was divided into five quantiles based on length. Within quantiles, a cluster analysis was performed on the basis of shape distance. Height, upward and downward slope, and progesterone level on Day 5 were compared between quantiles. Also, the ratio of typical versus atypical shapes was described, using a reference curve on the basis of data in Q1-Q4. The main results of this article were that (1) most of the progesterone profiles showed a typical profile, including the ones that exceeded the optimum cycle length of 24 days; (2) cycles in Q2 and Q3 had steeper slopes and higher peak progesterone levels than cycles in Q1 and Q4 but, when normalized, had a similar shape. Results were used to define differences between quantiles that can be used as templates. Compared to Q1, LLP's in Q2 had a shape that is 1.068 times steeper and 1.048 times higher. Luteal-like phases in Q3 were 1.053 times steeper and 1.018 times higher. Luteal-like phases in Q4 were 0.977 times steeper and 0.973 times higher than LLP's in Q1. This article adds to our knowledge about the variability of progesterone profiles and their shape differences. The profile clustering procedure described in this article can be used as a means to classify progesterone profiles without recourse to an a priori set of rules, which arbitrarily segment the natural variability in these profiles. Using data-derived profile shapes may allow a more accurate assessment of the effects of, e.g., nutritional management or breeding system on progesterone profiles. Copyright © 2016 Elsevier Inc. All rights reserved.

Gyrokinetic modeling of impurity peaking in JET H-mode plasmas

NASA Astrophysics Data System (ADS)

Manas, P.; Camenen, Y.; Benkadda, S.; Weisen, H.; Angioni, C.; Casson, F. J.; Giroud, C.; Gelfusa, M.; Maslov, M.

2017-06-01

Quantitative comparisons are presented between gyrokinetic simulations and experimental values of the carbon impurity peaking factor in a database of JET H-modes during the carbon wall era. These plasmas feature strong NBI heating and hence high values of toroidal rotation and corresponding gradient. Furthermore, the carbon profiles present particularly interesting shapes for fusion devices, i.e., hollow in the core and peaked near the edge. Dependencies of the experimental carbon peaking factor ( R / L nC ) on plasma parameters are investigated via multilinear regressions. A marked correlation between R / L nC and the normalised toroidal rotation gradient is observed in the core, which suggests an important role of the rotation in establishing hollow carbon profiles. The carbon peaking factor is then computed with the gyrokinetic code GKW, using a quasi-linear approach, supported by a few non-linear simulations. The comparison of the quasi-linear predictions to the experimental values at mid-radius reveals two main regimes. At low normalised collisionality, ν * , and T e / T i < 1 , the gyrokinetic simulations quantitatively recover experimental carbon density profiles, provided that rotodiffusion is taken into account. In contrast, at higher ν * and T e / T i > 1 , the very hollow experimental carbon density profiles are never predicted by the simulations and the carbon density peaking is systematically over estimated. This points to a possible missing ingredient in this regime.

The shape dependence of chameleon screening

NASA Astrophysics Data System (ADS)

Burrage, Clare; Copeland, Edmund J.; Moss, Adam; Stevenson, James A.

2018-01-01

Chameleon scalar fields can screen their associated fifth forces from detection by changing their mass with the local density. These models are an archetypal example of a screening mechanism, and have become an important target for both cosmological surveys and terrestrial experiments. In particular there has been much recent interest in searching for chameleon fifth forces in the laboratory. It is known that the chameleon force is less screened around non-spherical sources, but only the field profiles around a few simple shapes are known analytically. In this work we introduce a numerical code that solves for the chameleon field around arbitrary shapes with azimuthal symmetry placed in a spherical vacuum chamber. We find that deviations from spherical symmetry can increase the chameleon acceleration experienced by a test particle, and that the least screened objects are those which minimize some internal dimension. For the shapes considered in this work, keeping the mass, density and background environment fixed, the accelerations due to the source varied by a factor of ~ 3.

Profile Optimization Method for Robust Airfoil Shape Optimization in Viscous Flow

NASA Technical Reports Server (NTRS)

Li, Wu

2003-01-01

Simulation results obtained by using FUN2D for robust airfoil shape optimization in transonic viscous flow are included to show the potential of the profile optimization method for generating fairly smooth optimal airfoils with no off-design performance degradation.

Effects of tooth profile modification on dynamic responses of a high speed gear-rotor-bearing system

NASA Astrophysics Data System (ADS)

Hu, Zehua; Tang, Jinyuan; Zhong, Jue; Chen, Siyu; Yan, Haiyan

2016-08-01

A finite element node dynamic model of a high speed gear-rotor-bearing system considering the time-varying mesh stiffness, backlash, gyroscopic effect and transmission error excitation is developed. Different tooth profile modifications are introduced into the gear pair and corresponding time-varying mesh stiffness curves are obtained. Effects of the tooth profile modification on mesh stiffness are analyzed, and the natural frequencies and mode shapes of the gear-rotor-bearing transmission system are given. The dynamic responses with respect to a wide input speed region including dynamic factor, vibration amplitude near the bearing and dynamic transmission error are obtained by introducing the time-varying mesh stiffness in different tooth profile modification cases into the gear-rotor-bearing dynamic system. Effects of the tooth profile modification on the dynamic responses are studied in detail. The numerical simulation results show that both the short profile modification and the long profile modification can affect the mutation of the mesh stiffness when the number of engaging tooth pairs changes. A short profile modification with an appropriate modification amount can improve the dynamic property of the system in certain work condition.

Scaling of confinement and profiles in the EXTRAP T2 reversed-field pinch

NASA Astrophysics Data System (ADS)

Welander, A.

1999-01-01

In the EXTRAP T2 reversed-field pinch the diagnostic techniques for the measurement of electron density and temperature include; Thomson scattering which gives values at three radial positions in the core (r/a = 0, 0.28, 0.56), Langmuir probes which give values at the edge (r/a > 0.9) and interferometry which gives a line-averaged density. The empirical scaling of electron density and temperature including profile information with global plasma parameters has been studied. The density profile is subject to large variations, with an average parabolic shape when the density is low and flatter shapes when the density is increased. The change in the profile shape can be attributed to a shift in the penetration length of neutrals from the vicinity of the wall. The temperature scales roughly as I/n1/2 where I is the plasma current and n is the density. The temperature profile is always quite flat with lower variations and there is a tendency for a flatter profile at higher temperatures.

Sawtooth oscillations in shaped plasmas

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lazarus, E. A.; Luce, T. C.; Burrell, K. H.

The role of interchange and internal kink modes in the sawtooth oscillations is explored by comparing bean- and oval-shaped plasmas. The n=1 instability that results in the collapse of the sawtooth has been identified as a quasi-interchange in the oval cases and the internal kink in the bean shape. The ion and electron temperature profiles are followed in detail through the sawtooth ramp. It is found that electron energy transport rates are very high in the oval and quite low in the bean shape. Ion energy confinement in the oval is excellent and the sawtooth amplitude ({delta}T/T) in the ionmore » temperature is much larger than that of the electrons. The sawtooth amplitudes for ions and electrons are comparable in the bean shape. The measured q profiles in the bean and oval shapes are found to be consistent with neoclassical current diffusion of the toroidal current, and the observed differences in q largely result from the severe differences in electron energy transport. For both shapes the collapse flattens the q profile and after the collapse return to q{sub 0} > or approx. 1. Recent results on intermediate shapes are reported. These shapes show that the electron energy transport improves gradually as the plasma triangularity is increased.« less

SU-F-T-588: Asymmetries in the CyberKnife Iris 2 Collimator

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cernica, G; Ji, H; McRae, D

Purpose: The Iris 2 dodecahedral collimator in the CyberKnife unit can demonstrate visible asymmetry in the shaped radiation field, as seen on routine films. Specifically some edges of the collimator project longer than others. PDDs and output factors remain unaffected by this asymmetry. An in-house program was written to analyze the impact of this asymmetry on profiles. Methods: Two years of routine chromodynamic films were retrospectively analyzed using an in-house developed program. Films were obtained on a weekly basis in a plastic phantom on the vendor-provided mount. Profiles were obtained every degree. A dodecahedron was fitted to the 50% isodosemore » line and the positions and sizes of the upper and lower hexagonal collimators were derived. The collimators’ profiles at every degree, symmetry and centering were calculated and trended over the months. Results: Asymmetries in the obtained profiles were apparent. The upper and lower collimators were off-centered (0.31 mm, p<10–8), they did not project the same field size at 80 cm (0.46 mm difference, p<10–31). Profiles as a function of angle demonstrate a periodicity, but short and long profiles are rarely 15° apart, but vary from 9° to 21°. In addition, a second, intermediate minimum is seen at every other short profile. A trend in the field size over time is noted and can be monitored to identify servicing needs. Conclusion: Despite its differences, the asymmetric Iris 2 collimator did not demonstrate large deviations in PDDs and output factors. Due to the asymmetry, the 15° apart profiles obtained at commissioning do not represent the true large and short blade profiles of the collimator. Averaging of the profiles in the commissioning process hides this difference.« less

Profiling charge complementarity and selectivity for binding at the protein surface.

PubMed

Sulea, Traian; Purisima, Enrico O

2003-05-01

A novel analysis and representation of the protein surface in terms of electrostatic binding complementarity and selectivity is presented. The charge optimization methodology is applied in a probe-based approach that simulates the binding process to the target protein. The molecular surface is color coded according to calculated optimal charge or according to charge selectivity, i.e., the binding cost of deviating from the optimal charge. The optimal charge profile depends on both the protein shape and charge distribution whereas the charge selectivity profile depends only on protein shape. High selectivity is concentrated in well-shaped concave pockets, whereas solvent-exposed convex regions are not charge selective. This suggests the synergy of charge and shape selectivity hot spots toward molecular selection and recognition, as well as the asymmetry of charge selectivity at the binding interface of biomolecular systems. The charge complementarity and selectivity profiles map relevant electrostatic properties in a readily interpretable way and encode information that is quite different from that visualized in the standard electrostatic potential map of unbound proteins.

Design and characteristic analysis of shaping optics for optical trepanning

NASA Astrophysics Data System (ADS)

Zeng, D.; Latham, W. P.; Kar, A.

2005-08-01

Optical trepanning is a new laser drilling method using an annular beam. The annular beams allow numerous irradiance profiles to supply laser energy to the workpiece and thus provide more flexibility in affecting the hole quality than a traditional circular laser beam. The refractive axicon system has been designed to generating a collimated annular beam. In this article, calculations of intensity distributions produced by this refractive system are made by evaluating the Kirchhoff-Fresnel diffraction. It is shown that the refractive system is able to transform a Gaussian beam into a full Gaussian annular beam. The base angle of the axicon lens, input laser beam diameter and intensity profiles are found to be important factors for the axcion refractive system. Their effects on the annular beam profiles are analyzed based on the numerical solutions of the diffraction patterns.

Study of the Effect of Mold Corner Shape on the Initial Solidification Behavior of Molten Steel Using Mold Simulator

NASA Astrophysics Data System (ADS)

Lyu, Peisheng; Wang, Wanlin; Long, Xukai; Zhang, Kaixuan; Gao, Erzhuo; Qin, Rongshan

2018-02-01

The chamfered mold with a typical corner shape (angle between the chamfered face and hot face is 45 deg) was applied to the mold simulator study in this paper, and the results were compared with the previous results from a well-developed right-angle mold simulator system. The results suggested that the designed chamfered structure would increase the thermal resistance and weaken the two-dimensional heat transfer around the mold corner, causing the homogeneity of the mold surface temperatures and heat fluxes. In addition, the chamfered structure can decrease the fluctuation of the steel level and the liquid slag flow around the meniscus at mold corner. The cooling intensities at different longitudinal sections of shell are close to each other due to the similar time-average solidification factors, which are 2.392 mm/s1/2 (section A-A: chamfered center), 2.372 mm/s1/2 (section B-B: 135 deg corner), and 2.380 mm/s1/2 (section D-D: face), respectively. For the same oscillation mark (OM), the heights of OM roots at different positions (profile L1 (face), profile L2 (135 deg corner), and profile L3 (chamfered center)) are very close to each other. The average value of height difference (HD) between two OMs roots for L1 and L2 is 0.22 mm, and for L2 and L3 is 0.38 mm. Finally, with the help of metallographic examination, the shapes of different hooks were also discussed.

Optimization of Kink Stability in High-Beta Quasi-axisymmetric Stellarators

NASA Astrophysics Data System (ADS)

Fu, G. Y.; Ku, L.-P.; Manickam, J.; Cooper, W. A.

1998-11-01

A key issue for design of Quasi-axisymmetric stellarators( A. Reiman et al, this conference.) (QAS) is the stability of external kink modes driven by pressure-induced bootstrap current. In this work, the 3D MHD stability code TERPSICHORE(W.A. Cooper, Phys. Plasmas 3), 275(1996). is used to calculate the stability of low-n external kink modes in a high-beta QAS. The kink stability is optimized by adjusting plasma boundary shape (i.e., external coil configuration) as well as plasma pressure and current profiles. For this purpose, the TERPSICHORE code has been implemented successfully in an optimizer which maximizes kink stability as well as quasi-symmetry. A key factor for kink stability is rotational transform profile. It is found that the edge magnetic shear is strongly stabilizing. The amount of the shear needed for complete stabilization increases with edge transform. It is also found that the plasma boundary shape plays an important role in the kink stability besides transform profile. The physics mechanisms for the kink stability are being studied by examining the contributions of individual terms in δ W of the energy principle: the field line bending term, the current-driven term, the pressure-driven term, and the vacuum term. Detailed results will be reported.

Geomorphic effectiveness of long profile shape and role of inherent geological controls, Ganga River Basin, India

NASA Astrophysics Data System (ADS)

Sonam, Sonam; Jain, Vikrant

2017-04-01

River long profile is one of the fundamental geomorphic parameters which provides a platform to study interaction of geological and geomorphic processes at different time scales. Long profile shape is governed by geological processes at 10 ^ 5 - 10 ^ 6 years' time scale and it controls the modern day (10 ^ 0 - 10 ^ 1 years' time scale) fluvial processes by controlling the spatial variability of channel slope. Identification of an appropriate model for river long profile may provide a tool to analyse the quantitative relationship between basin geology, profile shape and its geomorphic effectiveness. A systematic analysis of long profiles has been carried for the Himalayan tributaries of the Ganga River basin. Long profile shape and stream power distribution pattern is derived using SRTM DEM data (90 m spatial resolution). Peak discharge data from 34 stations is used for hydrological analysis. Lithological variability and major thrusts are marked along the river long profile. The best fit of long profile is analysed for power, logarithmic and exponential function. Second order exponential function provides the best representation of long profiles. The second order exponential equation is Z = K1*exp(-β1*L) + K2*exp(-β2*L), where Z is elevation of channel long profile, L is the length, K and β are coefficients of the exponential function. K1 and K2 are the proportion of elevation change of the long profile represented by β1 (fast) and β2 (slow) decay coefficients of the river long profile. Different values of coefficients express the variability in long profile shapes and is related with the litho-tectonic variability of the study area. Channel slope of long profile is estimated taking the derivative of exponential function. Stream power distribution pattern along long profile is estimated by superimposing the discharge and long profile slope. Sensitivity analysis of stream power distribution with decay coefficients of the second order exponential equation is evaluated for a range of coefficient values. Our analysis suggests that the amplitude of stream power peak value is dependent on K1, the proportion of elevation change coming under the fast decay exponent and the location of stream power peak is dependent of the long profile decay coefficient (β1). Different long profile shapes owing to litho-tectonic variability across the Himalayas are responsible for spatial variability of stream power distribution pattern. Most of the stream power peaks lie in the Higher Himalaya. In general, eastern rivers have higher stream power in hinterland area and low stream power in the alluvial plains. This is responsible for, 1) higher erosion rate and sediment supply in hinterland of eastern rivers, 2) the incised and stable nature of channels in the western alluvial plains and 3) aggrading channels with dynamic nature in the eastern alluvial plains. Our study shows that the spatial variability of litho-units defines the coefficients of long profile function which in turn controls the position and magnitude of stream power maxima and hence the geomorphic variability in a fluvial system.

Implementation of a SVWP-based laser beam shaping technique for generation of 100-mJ-level picosecond pulses.

PubMed

Adamonis, J; Aleknavičius, A; Michailovas, K; Balickas, S; Petrauskienė, V; Gertus, T; Michailovas, A

2016-10-01

We present implementation of the energy-efficient and flexible laser beam shaping technique in a high-power and high-energy laser amplifier system. The beam shaping is based on a spatially variable wave plate (SVWP) fabricated by femtosecond laser nanostructuring of glass. We reshaped the initially Gaussian beam into a super-Gaussian (SG) of the 12th order with efficiency of about 50%. The 12th order of the SG beam provided the best compromise between large fill factor, low diffraction on the edges of the active media, and moderate intensity distribution modification during free-space propagation. We obtained 150 mJ pulses of 532 nm radiation. High-energy, pulse duration of 85 ps and the nearly flat-top spatial profile of the beam make it ideal for pumping optical parametric chirped pulse amplification systems.

Subwavelength elastic joints connecting torsional waveguides to maximize the power transmission coefficient

NASA Astrophysics Data System (ADS)

Lee, Joong Seok; Lee, Il Kyu; Seung, Hong Min; Lee, Jun Kyu; Kim, Yoon Young

2017-03-01

Joints with slowly varying tapered shapes, such as linear or exponential profiles, are known to transmit incident wave power efficiently between two waveguides with dissimilar impedances. This statement is valid only when the considered joint length is longer than the wavelengths of the incident waves. When the joint length is shorter than the wavelengths, however, appropriate shapes of such subwavelength joints for efficient power transmission have not been explored much. In this work, considering one-dimensional torsional wave motion in a cylindrical elastic waveguide system, optimal shapes or radial profiles of a subwavelength joint maximizing the power transmission coefficient are designed by a gradient-based optimization formulation. The joint is divided into a number of thin disk elements using the transfer matrix approach and optimal radii of the disks are determined by iterative shape optimization processes for several single or bands of wavenumbers. Due to the subwavelength constraint, the optimized joint profiles were found to be considerably different from the slowly varying tapered shapes. Specifically, for bands of wavenumbers, peculiar gourd-like shapes were obtained as optimal shapes to maximize the power transmission coefficient. Numerical results from the proposed optimization formulation were also experimentally realized to verify the validity of the present designs.

Early diffusion of gene expression profiling in breast cancer patients associated with areas of high income inequality.

PubMed

Ponce, Ninez A; Ko, Michelle; Liang, Su-Ying; Armstrong, Joanne; Toscano, Michele; Chanfreau-Coffinier, Catherine; Haas, Jennifer S

2015-04-01

With the Affordable Care Act reducing coverage disparities, social factors could prominently determine where and for whom innovations first diffuse in health care markets. Gene expression profiling is a potentially cost-effective innovation that guides chemotherapy decisions in early-stage breast cancer, but adoption has been uneven across the United States. Using a sample of commercially insured women, we evaluated whether income inequality in metropolitan areas was associated with receipt of gene expression profiling during its initial diffusion in 2006-07. In areas with high income inequality, gene expression profiling receipt was higher than elsewhere, but it was associated with a 10.6-percentage-point gap between high- and low-income women. In areas with low rates of income inequality, gene expression profiling receipt was lower, with no significant differences by income. Even among insured women, income inequality may indirectly shape diffusion of gene expression profiling, with benefits accruing to the highest-income patients in the most unequal places. Policies reducing gene expression profiling disparities should address low-inequality areas and, in unequal places, practice settings serving low-income patients. Project HOPE—The People-to-People Health Foundation, Inc.

Recommended Isolated-Line Profile for Representing High-Resolution Spectroscoscopic Transitions

NASA Astrophysics Data System (ADS)

Tennyson, J.; Bernath, P. F.; Campargue, A.; Császár, A. G.; Daumont, L.; Gamache, R. R.; Hodges, J. T.; Lisak, D.; Naumenko, O. V.; Rothman, L. S.; Tran, H.; Hartmann, J.-M.; Zobov, N. F.; Buldyreva, J.; Boone, C. D.; De Vizia, M. Domenica; Gianfrani, L.; McPheat, R.; Weidmann, D.; Murray, J.; Ngo, N. H.; Polyansky, O. L.

2014-06-01

Recommendations of an IUPAC Task Group, formed in 2011 on "Intensities and line shapes in high-resolution spectra of water isotopologues from experiment and theory" (Project No. 2011-022-2-100), on line profiles of isolated high-resolution rotational-vibrational transitions perturbed by neutral gas-phase molecules are presented. The well-documented inadequacies of the Voigt profile, used almost universally by databases and radiative-transfer codes to represent pressure effects and Doppler broadening in isolated vibrational-rotational and pure rotational transitions of the water molecule, have resulted in the development of a variety of alternative line profile models. These models capture more of the physics of the influence of pressure on line shapes but, in general, at the price of greater complexity. The Task Group recommends that the partially-Correlated quadratic-Speed-Dependent Hard-Collision profile should be adopted as the appropriate model for high-resolution spectroscopy. For simplicity this should be called the Hartmann-Tran profile (HTP). This profile is sophisticated enough to capture the various collisional contributions to the isolated line shape, can be computed in a straightforward and rapid manner, and reduces to simpler profiles, including the Voigt profile, under certain simplifying assumptions. For further details see: J. Tennyson et al, Pure Appl. Chem., 2014, in press.

Ω-slow Solutions and Be Star Disks

NASA Astrophysics Data System (ADS)

Araya, I.; Jones, C. E.; Curé, M.; Silaj, J.; Cidale, L.; Granada, A.; Jiménez, A.

2017-09-01

As the disk formation mechanism(s) in Be stars is(are) as yet unknown, we investigate the role of rapidly rotating radiation-driven winds in this process. We implemented the effects of high stellar rotation on m-CAK models accounting for the shape of the star, the oblate finite disk correction factor, and gravity darkening. For a fast rotating star, we obtain a two-component wind model, I.e., a fast, thin wind in the polar latitudes and an Ω-slow, dense wind in the equatorial regions. We use the equatorial mass densities to explore Hα emission profiles for the following scenarios: (1) a spherically symmetric star, (2) an oblate star with constant temperature, and (3) an oblate star with gravity darkening. One result of this work is that we have developed a novel method for solving the gravity-darkened, oblate m-CAK equation of motion. Furthermore, from our modeling we find that (a) the oblate finite disk correction factor, for the scenario considering the gravity darkening, can vary by at least a factor of two between the equatorial and polar directions, influencing the velocity profile and mass-loss rate accordingly, (b) the Hα profiles predicted by our model are in agreement with those predicted by a standard power-law model for following values of the line-force parameters: 1.5≲ k≲ 3,α ˜ 0.6, and δ ≳ 0.1, and (c) the contribution of the fast wind component to the Hα emission line profile is negligible; therefore, the line profiles arise mainly from the equatorial disks of Be stars.

Microbial community dynamics in soil aggregates shape biogeochemical gas fluxes from soil profiles - upscaling an aggregate biophysical model.

PubMed

Ebrahimi, Ali; Or, Dani

2016-09-01

Microbial communities inhabiting soil aggregates dynamically adjust their activity and composition in response to variations in hydration and other external conditions. These rapid dynamics shape signatures of biogeochemical activity and gas fluxes emitted from soil profiles. Recent mechanistic models of microbial processes in unsaturated aggregate-like pore networks revealed a highly dynamic interplay between oxic and anoxic microsites jointly shaped by hydration conditions and by aerobic and anaerobic microbial community abundance and self-organization. The spatial extent of anoxic niches (hotspots) flicker in time (hot moments) and support substantial anaerobic microbial activity even in aerated soil profiles. We employed an individual-based model for microbial community life in soil aggregate assemblies represented by 3D angular pore networks. Model aggregates of different sizes were subjected to variable water, carbon and oxygen contents that varied with soil depth as boundary conditions. The study integrates microbial activity within aggregates of different sizes and soil depth to obtain estimates of biogeochemical fluxes from the soil profile. The results quantify impacts of dynamic shifts in microbial community composition on CO2 and N2 O production rates in soil profiles in good agreement with experimental data. Aggregate size distribution and the shape of resource profiles in a soil determine how hydration dynamics shape denitrification and carbon utilization rates. Results from the mechanistic model for microbial activity in aggregates of different sizes were used to derive parameters for analytical representation of soil biogeochemical processes across large scales of practical interest for hydrological and climate models. © 2016 John Wiley & Sons Ltd.

How do cuticular hydrocarbons evolve? Physiological constraints and climatic and biotic selection pressures act on a complex functional trait

PubMed Central

Blaimer, Bonnie B.; Schmitt, Thomas

2017-01-01

Cuticular hydrocarbons (CHCs) cover the cuticles of virtually all insects, serving as a waterproofing agent and as a communication signal. The causes for the high CHC variation between species, and the factors influencing CHC profiles, are scarcely understood. Here, we compare CHC profiles of ant species from seven biogeographic regions, searching for physiological constraints and for climatic and biotic selection pressures. Molecule length constrained CHC composition: long-chain profiles contained fewer linear alkanes, but more hydrocarbons with disruptive features in the molecule. This is probably owing to selection on the physiology to build a semi-fluid cuticular layer, which is necessary for waterproofing and communication. CHC composition also depended on the precipitation in the ants' habitats. Species from wet climates had more alkenes and fewer dimethyl alkanes than those from drier habitats, which can be explained by different waterproofing capacities of these compounds. By contrast, temperature did not affect CHC composition. Mutualistically associated (parabiotic) species possessed profiles highly distinct from non-associated species. Our study is, to our knowledge, the first to show systematic impacts of physiological, climatic and biotic factors on quantitative CHC composition across a global, multi-species dataset. We demonstrate how they jointly shape CHC profiles, and advance our understanding of the evolution of this complex functional trait in insects. PMID:28298343

Effect of Capillary Tube’s Shape on Capillary Rising Regime for Viscos Fluids

NASA Astrophysics Data System (ADS)

Soroush, F.; Moosavi, A.

2018-05-01

When properties of the displacing fluid are considered, the rising profile of the penetrating fluid in a capillary tube deviates from its classical Lucas-Washburn profile. Also, shape of capillary tube can affect the rising profile in different aspects. In this article, effect of capillary tube’s shape on the vertical capillary motion in presence of gravity is investigated by considering the properties of the displacing fluid. According to the fact that the differential equation of the capillary rising for a non-simple wall type is very difficult to solve analytically, a finite element simulation model is used for this study. After validation of the simulation model with an experiment that has been done with a simple capillary tube, shape of the capillary tube’s wall is changed in order to understand its effects on the capillary rising and different motion regimes that may appear according to different geometries. The main focus of this article is on the sinusoidal wall shapes and comparing them with a simple wall.

Theory of Epithelial Cell Shape Transitions Induced by Mechanoactive Chemical Gradients.

PubMed

Dasbiswas, Kinjal; Hannezo, Edouard; Gov, Nir S

2018-02-27

Cell shape is determined by a balance of intrinsic properties of the cell as well as its mechanochemical environment. Inhomogeneous shape changes underlie many morphogenetic events and involve spatial gradients in active cellular forces induced by complex chemical signaling. Here, we introduce a mechanochemical model based on the notion that cell shape changes may be induced by external diffusible biomolecules that influence cellular contractility (or equivalently, adhesions) in a concentration-dependent manner-and whose spatial profile in turn is affected by cell shape. We map out theoretically the possible interplay between chemical concentration and cellular structure. Besides providing a direct route to spatial gradients in cell shape profiles in tissues, we show that the dependence on cell shape helps create robust mechanochemical gradients. Copyright © 2017 Biophysical Society. Published by Elsevier Inc. All rights reserved.

The role of tidal current characteristics on the development of intertidal morphology in tropical and subtropical mangrove forests

NASA Astrophysics Data System (ADS)

Bryan, K. R.; Nardin, W.; Fagherazzi, S.; Mullarney, J. C.; Norris, B. K.; Henderson, S. M.

2016-12-01

Mangroves are a common intertidal species in tropical and sub-tropical environments, with growth forms that vary substantially between species such as the pencil roots in Avicennia, the prop or stilt roots of Rhizophora and the knee roots in Bruguiera. Here we investigate the role root and tree structures may play on the longterm development of intertidal morphology in mangrove-dominated environments. We use a one-dimensional Delft3D numerical simulation in conjunction with a simple model to determine that the dominant controls on the tidally-driven momentum balance are the frictional characteristics of the forest, which delay the propagation of the tide into the forest. Details of the vegetation at the seaward fringe along with sediment grain size determine the shape of the ensuing profile, with sparser vegetation and coarser grainsizes creating more linear profiles whereas denser vegetation and finer grainsizes generating convex intertidal profiles. Examples showing these different profile developments are provided from the Mekong Delta in Vietnam, which tends to a linear profile, and the Firth of Thames in New Zealand, which has a distinctive convex profile. Preliminary validation using current meter measurements from the Mekong Delta show that the currents diminish quickly between the mudflat seaward of the forest and the fringe, then remain fairly constant several hundred meters into the forest indicating that this linear profile has probably developed into an equilibrium shape. Understanding the forces that shape the development of the intertidal profile shape is critical to predicting the resilience of these sensitive intertidal areas to changes in inundation caused by sea level rise.

Constant- q data representation in Neutron Compton scattering on the VESUVIO spectrometer

NASA Astrophysics Data System (ADS)

Senesi, R.; Pietropaolo, A.; Andreani, C.

2008-09-01

Standard data analysis on the VESUVIO spectrometer at ISIS is carried out within the Impulse Approximation framework, making use of the West scaling variable y. The experiments are performed using the time-of-flight technique with the detectors positioned at constant scattering angles. Line shape analysis is routinely performed in the y-scaling framework, using two different (and equivalent) approaches: (1) fitting the parameters of the recoil peaks directly to fixed-angle time-of-flight spectra; (2) transforming the time-of-flight spectra into fixed-angle y spectra, referred to as the Neutron Compton Profiles, and then fitting the line shape parameters. The present work shows that scattering signals from different fixed-angle detectors can be collected and rebinned to obtain Neutron Compton Profiles at constant wave vector transfer, q, allowing for a suitable interpretation of data in terms of the dynamical structure factor, S(q,ω). The current limits of applicability of such a procedure are discussed in terms of the available q-range and relative uncertainties for the VESUVIO experimental set up and of the main approximations involved.

Shapes of star-gas waves in spiral galaxies

NASA Technical Reports Server (NTRS)

Lubow, Stephen H.

1988-01-01

Density-wave profile shapes are influenced by several effects. By solving viscous fluid equations, the nonlinear effects of the gas and its gravitational interaction with the stars can be analyzed. The stars are treated through a linear theory developed by Lin and coworkers. Short wavelength gravitational forces are important in determining the gas density profile shape. With the inclusion of disk finite thickness effects, the gas gravitational field remains important, but is significantly reduced at short wavelengths. Softening of the gas equation of state results in an enhanced response and a smoothing of the gas density profile. A Newtonian stress relation is marginally acceptable for HI gas clouds, but not acceptable for giant molecular clouds.

A weak lensing analysis of the PLCK G100.2-30.4 cluster

NASA Astrophysics Data System (ADS)

Radovich, M.; Formicola, I.; Meneghetti, M.; Bartalucci, I.; Bourdin, H.; Mazzotta, P.; Moscardini, L.; Ettori, S.; Arnaud, M.; Pratt, G. W.; Aghanim, N.; Dahle, H.; Douspis, M.; Pointecouteau, E.; Grado, A.

2015-07-01

We present a mass estimate of the Planck-discovered cluster PLCK G100.2-30.4, derived from a weak lensing analysis of deep Subaru griz images. We perform a careful selection of the background galaxies using the multi-band imaging data, and undertake the weak lensing analysis on the deep (1 h) r -band image. The shape measurement is based on the Kaiser-Squires-Broadhurst algorithm; we adopt the PSFex software to model the point spread function (PSF) across the field and correct for this in the shape measurement. The weak lensing analysis is validated through extensive image simulations. We compare the resulting weak lensing mass profile and total mass estimate to those obtained from our re-analysis of XMM-Newton observations, derived under the hypothesis of hydrostatic equilibrium. The total integrated mass profiles agree remarkably well, within 1σ across their common radial range. A mass M500 ~ 7 × 1014M⊙ is derived for the cluster from our weak lensing analysis. Comparing this value to that obtained from our reanalysis of XMM-Newton data, we obtain a bias factor of (1-b) = 0.8 ± 0.1. This is compatible within 1σ with the value of (1-b) obtained in Planck 2015 from the calibration of the bias factor using newly available weak lensing reconstructed masses. Based on data collected at Subaru Telescope (University of Tokyo).

Waste disposal and households' heterogeneity. Identifying factors shaping attitudes towards source-separated recycling in Bogotá, Colombia.

PubMed

J Padilla, Alcides; Trujillo, Juan C

2018-04-01

Solid waste management in many cities of developing countries is not environmentally sustainable. People traditionally dispose of their solid waste in unsuitable urban areas like sidewalks and satellite dumpsites. This situation nowadays has become a serious public health problem in big Latin American conurbations. Among these densely-populated urban spaces, the Colombia's capital and main city stands out as a special case. In this study, we aim to identify the factors that shape the attitudes towards source-separated recycling among households in Bogotá. Using data from the Colombian Department of Statistics and Bogotá's multi-purpose survey, we estimated a multivariate Probit model. In general, our results show that the higher the household's socioeconomic class, the greater its effort for separating solid wastes. Likewise, our findings also allowed us to characterize household profiles regarding solid waste separation and considering each socioeconomic class. Among these profiles, we found that at lower socioeconomic classes, the attitudes towards solid waste separation are influenced by the use of Internet, the membership to an environmentalist organization, the level of education of the head of household and the homeownership. Hence, increasing the education levels within the poorest segment of the population, promoting affordable housing policies and facilitating Internet access for the vulnerable population could reinforce households' attitudes towards a greater source-separated recycling effort. Copyright © 2017 Elsevier Ltd. All rights reserved.

The generalization of upper atmospheric wind and temperature based on the Voigt line shape profile.

PubMed

Zhang, Chunmin; He, Jian

2006-12-25

The principle of probing the upper atmospheric wind field, which is the Voigt profile spectral line shape, is presented for the first time. By the Fourier Transform of Voigt profile, with the Imaging Spectroscope and the Doppler effect of electromagnetic wave, the distribution and calculation formulae of the velocity field, temperature field, and pressure field of the upper atmosphere wind field are given. The probed source is the two major aurora emission lines originated from the metastable O(1S) and O(1D) at 557.7nm and 630.0nm. From computer simulation and error analysis, the Voigt profile, which is the correlation of the Gaussian profile and Lorentzian profile, is closest to the actual airglow emission lines.

Voigt spectral profiles in two-photon resonance fluorescence

DOE Office of Scientific and Technical Information (OSTI.GOV)

Alexanian, Moorad; Bose, Subir K.; Department of Physics, University of Central Florida, Orlando, Florida 32816

2007-11-15

A recent work on two-photon fluorescence is extended by considering the pump field to be a coherent state, which represents a laser field operating well above threshold. The dynamical conditions are investigated under which the two-photon spectrum gives rise, in addition to a Lorentzian line shape at the pump frequency, to two Voigt spectral sideband profiles. Additional conditions are found under which the Voigt profile behaves like either a Gaussian or a Lorentzian line shape.

Spectral shapes of rovibrational lines of CO broadened by He, Ar, Kr and SF6: A test case of the Hartmann-Tran profile

NASA Astrophysics Data System (ADS)

Ngo, N. H.; Lin, H.; Hodges, J. T.; Tran, H.

2017-12-01

High signal-to-noise ratio spectra of the (3-0) band P(1) and P(17) lines of CO broadened by He, Ar, Kr and SF6 were measured with a frequency-stabilized cavity ring-down spectroscopy system. For each collision-partner and both lines, multiple spectra were measured over pressures spanning nearly three decades up to 130 kPa. These data were analyzed with a multispectrum fitting procedure. Line shapes were modeled using the Hartmann-Tran (HT) profile with first-order line mixing as well as several other simplified profiles. The results show that for all considered collision partners (with the exception of SF6), the HT profile captures the measured line shapes with maximum absolute residuals that are within 0.1% of the peak absorption. In the case of SF6, which is the heaviest perturber investigated here, the maximum residuals for the HT profile are twice as large as for the other collision partners.

Profiling Charge Complementarity and Selectivity for Binding at the Protein Surface

PubMed Central

Sulea, Traian; Purisima, Enrico O.

2003-01-01

A novel analysis and representation of the protein surface in terms of electrostatic binding complementarity and selectivity is presented. The charge optimization methodology is applied in a probe-based approach that simulates the binding process to the target protein. The molecular surface is color coded according to calculated optimal charge or according to charge selectivity, i.e., the binding cost of deviating from the optimal charge. The optimal charge profile depends on both the protein shape and charge distribution whereas the charge selectivity profile depends only on protein shape. High selectivity is concentrated in well-shaped concave pockets, whereas solvent-exposed convex regions are not charge selective. This suggests the synergy of charge and shape selectivity hot spots toward molecular selection and recognition, as well as the asymmetry of charge selectivity at the binding interface of biomolecular systems. The charge complementarity and selectivity profiles map relevant electrostatic properties in a readily interpretable way and encode information that is quite different from that visualized in the standard electrostatic potential map of unbound proteins. PMID:12719221

Diffractive beam shaping for enhanced laser polymer welding

NASA Astrophysics Data System (ADS)

Rauschenberger, J.; Vogler, D.; Raab, C.; Gubler, U.

2015-03-01

Laser welding of polymers increasingly finds application in a large number of industries such as medical technology, automotive, consumer electronics, textiles or packaging. More and more, it replaces other welding technologies for polymers, e. g. hot-plate, vibration or ultrasonic welding. At the same rate, demands on the quality of the weld, the flexibility of the production system and on processing speed have increased. Traditionally, diode lasers were employed for plastic welding with flat-top beam profiles. With the advent of fiber lasers with excellent beam quality, the possibility to modify and optimize the beam profile by beam-shaping elements has opened. Diffractive optical elements (DOE) can play a crucial role in optimizing the laser intensity profile towards the optimal M-shape beam for enhanced weld seam quality. We present results on significantly improved weld seam width constancy and enlarged process windows compared to Gaussian or flat-top beam profiles. Configurations in which the laser beam diameter and shape can be adapted and optimized without changing or aligning the laser, fiber-optic cable or optical head are shown.

Linear shaped charge

DOEpatents

Peterson, David; Stofleth, Jerome H.; Saul, Venner W.

2017-07-11

Linear shaped charges are described herein. In a general embodiment, the linear shaped charge has an explosive with an elongated arrowhead-shaped profile. The linear shaped charge also has and an elongated v-shaped liner that is inset into a recess of the explosive. Another linear shaped charge includes an explosive that is shaped as a star-shaped prism. Liners are inset into crevices of the explosive, where the explosive acts as a tamper.

Mars Ozone Absorption Line Shapes from Infrared Heterodyne Spectra Applied to GCM-Predicted Ozone Profiles and to MEX/SPICAM Column Retrievals

NASA Technical Reports Server (NTRS)

Fast, Kelly E.; Kostiuk, T.; Annen, J.; Hewagama, T.; Delgado, J.; Livengood, T. A.; Lefevre, F.

2008-01-01

We present the application of infrared heterodyne line shapes of ozone on Mars to those produced by radiative transfer modeling of ozone profiles predicted by general circulation models (GCM), and to contemporaneous column abundances measured by Mars Express SPICAM. Ozone is an important tracer of photochemistry Mars' atmosphere, serving as an observable with which to test predictions of photochemistry-coupled GCMs. Infrared heterodyne spectroscopy at 9.5 microns with spectral resolving power >1,000,000 is the only technique that can directly measure fully-resolved line shapes of Martian ozone features from the surface of the Earth. Measurements were made with Goddard Space Flight Center's Heterodyne instrument for Planetary Wind And Composition (HIPWAC) at the NASA Infrared Telescope Facility (IRTF) on Mauna Kea, Hawaii on February 21-24 2008 UT at Ls=35deg on or near the MEX orbital path. The HIPWAC observations were used to test GCM predictions. For example, a GCM-generated ozone profile for 60degN 112degW was scaled so that a radiative transfer calculation of its absorption line shape matched an observed HIPWAC absorption feature at the same areographic position, local time, and season. The RMS deviation of the model from the data was slightly smaller for the GCM-generated profile than for a line shape produced by a constant-with-height profile, even though the total column abundances were the same, showing potential for testing and constraining GCM ozone-profiles. The resulting ozone column abundance from matching the model to the HIPWAC line shape was 60% higher than that observed by SPICAM at the same areographic position one day earlier and 2.5 hours earlier in local time. This could be due to day-to-day, diurnal, or north polar region variability, or to measurement sensitivity to the ozone column and its distribution, and these possibilities will be explored. This work was supported by NASA's Planetary Astronomy Program.

Method for shaping sheet thermoplastic and the like

NASA Technical Reports Server (NTRS)

Akilian, Mireille K. (Inventor); Schattenburg, Mark L. (Inventor)

2011-01-01

Processes and apparati for shaping sheet glass or thermoplastic materials use force from a layer of a flowing fluid, such as air, between the sheet and a mandrel at close to the softening temperature of the thermoplastic. The shape is preserved by cooling. The shape of the air bearing mandrel and the pressure distribution of the fluid contribute to the final shape. A process can be conducted on one or two surfaces such that the force from the air layer is on one or two surfaces of the sheet. The gap size between the sheet and mandrel determines the pressure profile in the gap, which also determines the final sheet shape. In general, smaller gaps lead to larger viscous forces. The pressure profile depends on the shape of the mandrel, the size of the fluid gap and the sheet and the fluid supply pressure.

Scanning electron microscope measurement of width and shape of 10nm patterned lines using a JMONSEL-modeled library.

PubMed

Villarrubia, J S; Vladár, A E; Ming, B; Kline, R J; Sunday, D F; Chawla, J S; List, S

2015-07-01

The width and shape of 10nm to 12 nm wide lithographically patterned SiO2 lines were measured in the scanning electron microscope by fitting the measured intensity vs. position to a physics-based model in which the lines' widths and shapes are parameters. The approximately 32 nm pitch sample was patterned at Intel using a state-of-the-art pitch quartering process. Their narrow widths and asymmetrical shapes are representative of near-future generation transistor gates. These pose a challenge: the narrowness because electrons landing near one edge may scatter out of the other, so that the intensity profile at each edge becomes width-dependent, and the asymmetry because the shape requires more parameters to describe and measure. Modeling was performed by JMONSEL (Java Monte Carlo Simulation of Secondary Electrons), which produces a predicted yield vs. position for a given sample shape and composition. The simulator produces a library of predicted profiles for varying sample geometry. Shape parameter values are adjusted until interpolation of the library with those values best matches the measured image. Profiles thereby determined agreed with those determined by transmission electron microscopy and critical dimension small-angle x-ray scattering to better than 1 nm. Published by Elsevier B.V.

The Composition and Spatial Patterns of Bacterial Virulence Factors and Antibiotic Resistance Genes in 19 Wastewater Treatment Plants

PubMed Central

Zhang, Bing; Xia, Yu; Wen, Xianghua; Wang, Xiaohui; Yang, Yunfeng; Zhou, Jizhong; Zhang, Yu

2016-01-01

Bacterial pathogenicity and antibiotic resistance are of concern for environmental safety and public health. Accumulating evidence suggests that wastewater treatment plants (WWTPs) are as an important sink and source of pathogens and antibiotic resistance genes (ARGs). Virulence genes (encoding virulence factors) are good indicators for bacterial pathogenic potentials. To achieve a comprehensive understanding of bacterial pathogenic potentials and antibiotic resistance in WWTPs, bacterial virulence genes and ARGs in 19 WWTPs covering a majority of latitudinal zones of China were surveyed by using GeoChip 4.2. A total of 1610 genes covering 13 virulence factors and 1903 genes belonging to 11 ARG families were detected respectively. The bacterial virulence genes exhibited significant spatial distribution patterns of a latitudinal biodiversity gradient and a distance-decay relationship across China. Moreover, virulence genes tended to coexist with ARGs as shown by their strongly positive associations. In addition, key environmental factors shaping the overall virulence gene structure were identified. This study profiles the occurrence, composition and distribution of virulence genes and ARGs in current WWTPs in China, and uncovers spatial patterns and important environmental variables shaping their structure, which may provide the basis for further studies of bacterial virulence factors and antibiotic resistance in WWTPs. PMID:27907117

80GHz waveform generator by optical Fourier synthesis of four spectral sidebands (Conference Presentation)

NASA Astrophysics Data System (ADS)

Fatome, Julien; Hammani, Kamal; Kibler, Bertrand; Finot, Christophe

2016-04-01

Versatile and easy to implement methods to generate arbitrary optical waveforms at high repetition rates are of considerable interest with applications in optical communications, all-optical signal processing, instrumentation systems and microwave signal manipulation. While shaping sinusoidal, Gaussian or hyperbolic secant intensity profiles is commonly achieved by means of modulators or mode-locked lasers, other pulse profiles such as parabolic, triangular or flat-top shapes still remain challenging to synthesize. In this context, several strategies were already explored. First, the linear pulse shaping is a common method to carve an initial ultrashort pulse train into the desired shape. The line-by-line shaping of a coherent frequency comb made of tens of spectral components was also investigated to generate more complex structures whereas Fourier synthesis of a few discrete frequencies spectrum was exploited to efficiently generate high-fidelity ultrafast periodic intensity profiles. Besides linear shaping techniques, several nonlinear methods were implemented to benefit from the adiabatic evolution of the intensity pulse profile upon propagation in optical fibers. Other examples of efficient methods are based on the photonic generation involving specific Mach-Zehnder modulators, microwave photonic filters as well as frequency-to-time conversion. In this contribution, we theoretically and experimentally demonstrate a new approach enabling the synthesis of periodic high-repetition rate pulses with various intensity profiles ranging from parabola to triangular and flat-top pulses. More precisely by linear phase and amplitude shaping of only four spectral lines is it possible to reach the targeted temporal profile. Indeed, tailoring the input symmetric spectrum only requires the determination of two physical parameters: the phase difference between the inner and outer spectral sidebands and the ratio between the amplitude of these sidebands. Therefore, a systematic bidimensional analysis provides the optimum parameters and also highlights that switching between the different waveforms is achieved by simply changing the spectral phase between the inner and outer sidebands. We successfully validate this concept with the generation of high-fidelity ultrafast periodic waveforms at 40 GHz by shaping with a liquid cristal on insulator a four sideband comb resulting from a phase-modulated continuous wave. In order to reach higher repetition rates, we also describe a new scenario to obtain the required initial spectrum by taking advantage of the four-wave mixing process occurring in a highly nonlinear fiber. This approach is experimentally implemented at a repetition rate of 80-GHz by use of intensity and phase measurements that stress that full-duty cycle, high-quality, triangular, parabolic or flat-top profiles are obtained in full agreement with numerical simulations. The reconfigurable property of this photonic waveform generator is confirmed. Finally, the generation of bunch of shaped pulses is investigated, as well as the impact of Brillouin backscattering.

On Machine Capacitance Dimensional and Surface Profile Measurement System

NASA Technical Reports Server (NTRS)

Resnick, Ralph

1993-01-01

A program was awarded under the Air Force Machine Tool Sensor Improvements Program Research and Development Announcement to develop and demonstrate the use of a Capacitance Sensor System including Capacitive Non-Contact Analog Probe and a Capacitive Array Dimensional Measurement System to check the dimensions of complex shapes and contours on a machine tool or in an automated inspection cell. The manufacturing of complex shapes and contours and the subsequent verification of those manufactured shapes is fundamental and widespread throughout industry. The critical profile of a gear tooth; the overall shape of a graphite EDM electrode; the contour of a turbine blade in a jet engine; and countless other components in varied applications possess complex shapes that require detailed and complex inspection procedures. Current inspection methods for complex shapes and contours are expensive, time-consuming, and labor intensive.

Ocean plankton. Determinants of community structure in the global plankton interactome.

PubMed

Lima-Mendez, Gipsi; Faust, Karoline; Henry, Nicolas; Decelle, Johan; Colin, Sébastien; Carcillo, Fabrizio; Chaffron, Samuel; Ignacio-Espinosa, J Cesar; Roux, Simon; Vincent, Flora; Bittner, Lucie; Darzi, Youssef; Wang, Jun; Audic, Stéphane; Berline, Léo; Bontempi, Gianluca; Cabello, Ana M; Coppola, Laurent; Cornejo-Castillo, Francisco M; d'Ovidio, Francesco; De Meester, Luc; Ferrera, Isabel; Garet-Delmas, Marie-José; Guidi, Lionel; Lara, Elena; Pesant, Stéphane; Royo-Llonch, Marta; Salazar, Guillem; Sánchez, Pablo; Sebastian, Marta; Souffreau, Caroline; Dimier, Céline; Picheral, Marc; Searson, Sarah; Kandels-Lewis, Stefanie; Gorsky, Gabriel; Not, Fabrice; Ogata, Hiroyuki; Speich, Sabrina; Stemmann, Lars; Weissenbach, Jean; Wincker, Patrick; Acinas, Silvia G; Sunagawa, Shinichi; Bork, Peer; Sullivan, Matthew B; Karsenti, Eric; Bowler, Chris; de Vargas, Colomban; Raes, Jeroen

2015-05-22

Species interaction networks are shaped by abiotic and biotic factors. Here, as part of the Tara Oceans project, we studied the photic zone interactome using environmental factors and organismal abundance profiles and found that environmental factors are incomplete predictors of community structure. We found associations across plankton functional types and phylogenetic groups to be nonrandomly distributed on the network and driven by both local and global patterns. We identified interactions among grazers, primary producers, viruses, and (mainly parasitic) symbionts and validated network-generated hypotheses using microscopy to confirm symbiotic relationships. We have thus provided a resource to support further research on ocean food webs and integrating biological components into ocean models. Copyright © 2015, American Association for the Advancement of Science.

Poster — Thur Eve — 02: Measurement of CT radiation profile width using Fuji CR imaging plate raw data

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bjarnason, T A; Department of Radiology, University of British Columbia, Vancouver; Yang, C J

2014-08-15

Measuring the CT collimation width and assessing the shape of the overall profile is a relatively straightforward quality control (QC) measure that impacts both image quality and patient dose, and is often required at acceptance and routine testing. Most CT facilities have access to computed radiography (CR) systems, so performing CT collimation profile assessments using CR plates requires no additional equipment. Previous studies have shown how to effectively use CR plates to measure the radiation profile width. However, a major limitation of the previous work is that the full dynamic range of CR detector plates are not used, since themore » CR processing technology reduces the dynamic range of the DICOM output to 2{sup 10}, requiring the sensitivity and latitude settings of CR reader to be adjusted to prevent clipping of the CT profile data. Such adjustments to CR readers unnecessarily complicate the QC procedure. These clipping artefacts hinder the ability to accurately assess CT collimation width because the full-width at half maximum value of the penumbras are not properly determined if the maximum dose of the profile is not available. Furthermore, any inconsistencies in the radiation profile shape are lost if the profile plateau is clipped off. In this work we developed an opensource Matlab script for straightforward CT profile width measurements using raw CR data that also allows assessment of the profile shape without clipping, and applied this approach during CT QC.« less

The effect of internal magnetic structure on the fishbone instability

DOE Office of Scientific and Technical Information (OSTI.GOV)

Roberts, D.W.; Powell, E.; Kaita, R.

1992-01-01

Plasmas exhibiting the ``fishbone`` instability studied on the PBX-M tokamak show a distinct relationship between the plasma shape, the internal magnetic structure, and the presence or absence of fast ion losses associated with the fishbone mode. We have, for the first time, carried out measurements of the magnetic safety factor profile in fishbone-unstable plasmas, and used the knowledge of the associated experimental equilibria to compare the stability and fast ion loss properties of these plasmas with experimental observations.

The effect of internal magnetic structure on the fishbone instability

DOE Office of Scientific and Technical Information (OSTI.GOV)

Roberts, D.W.; Powell, E.; Kaita, R.

1992-01-01

Plasmas exhibiting the fishbone'' instability studied on the PBX-M tokamak show a distinct relationship between the plasma shape, the internal magnetic structure, and the presence or absence of fast ion losses associated with the fishbone mode. We have, for the first time, carried out measurements of the magnetic safety factor profile in fishbone-unstable plasmas, and used the knowledge of the associated experimental equilibria to compare the stability and fast ion loss properties of these plasmas with experimental observations.

The mathematical and computer modeling of the worm tool shaping

NASA Astrophysics Data System (ADS)

Panchuk, K. L.; Lyashkov, A. A.; Ayusheev, T. V.

2017-06-01

Traditionally mathematical profiling of the worm tool is carried out on the first T. Olivier method, known in the theory of gear gearings, with receiving an intermediate surface of the making lath. It complicates process of profiling and its realization by means of computer 3D-modeling. The purpose of the work is the improvement of mathematical model of profiling and its realization based on the methods of 3D-modeling. Research problems are: receiving of the mathematical model of profiling which excludes the presence of the making lath in it; realization of the received model by means of frame and superficial modeling; development and approbation of technology of solid-state modeling for the solution of the problem of profiling. As the basic, the kinematic method of research of the mutually envelope surfaces is accepted. Computer research is executed by means of CAD based on the methods of 3D-modeling. We have developed mathematical model of profiling of the worm tool; frame, superficial and solid-state models of shaping of the mutually enveloping surfaces of the detail and the tool are received. The offered mathematical models and the technologies of 3D-modeling of shaping represent tools for theoretical and experimental profiling of the worm tool. The results of researches can be used at design of metal-cutting tools.

THE MASS PROFILE AND SHAPE OF BARS IN THE SPITZER SURVEY OF STELLAR STRUCTURE IN GALAXIES (S{sup 4}G): SEARCH FOR AN AGE INDICATOR FOR BARS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kim, Taehyun; Lee, Myung Gyoon; Sheth, Kartik

2015-01-20

We have measured the radial light profiles and global shapes of bars using two-dimensional 3.6 μm image decompositions for 144 face-on barred galaxies from the Spitzer Survey of Stellar Structure in Galaxies. The bar surface brightness profile is correlated with the stellar mass and bulge-to-total (B/T) ratio of their host galaxies. Bars in massive and bulge-dominated galaxies (B/T > 0.2) show a flat profile, while bars in less massive, disk-dominated galaxies (B/T ∼ 0) show an exponential, disk-like profile with a wider spread in the radial profile than in the bulge-dominated galaxies. The global two-dimensional shapes of bars, however, are rectangular/boxy, independentmore » of the bulge or disk properties. We speculate that because bars are formed out of disks, bars initially have an exponential (disk-like) profile that evolves over time, trapping more disk stars to boxy bar orbits. This leads bars to become stronger and have flatter profiles. The narrow spread of bar radial profiles in more massive disks suggests that these bars formed earlier (z > 1), while the disk-like profiles and a larger spread in the radial profile in less massive systems imply a later and more gradual evolution, consistent with the cosmological evolution of bars inferred from observational studies. Therefore, we expect that the flatness of the bar profile can be used as a dynamical age indicator of the bar to measure the time elapsed since the bar formation. We argue that cosmic gas accretion is required to explain our results on bar profile and the presence of gas within the bar region.« less

Adaptive temperature profile control of a multizone crystal growth furnace

NASA Technical Reports Server (NTRS)

Batur, C.; Sharpless, R. B.; Duval, W. M. B.; Rosenthal, B. N.

1991-01-01

An intelligent measurement system is described which is used to assess the shape of a crystal while it is growing inside a multizone transparent furnace. A color video imaging system observes the crystal in real time, and determines the position and the shape of the interface. This information is used to evaluate the crystal growth rate, and to analyze the effects of translational velocity and temperature profiles on the shape of the interface. Creation of this knowledge base is the first step to incorporate image processing into furnace control.

Flow over Canopies with Complex Morphologies

NASA Astrophysics Data System (ADS)

Rubol, S.; Ling, B.; Battiato, I.

2017-12-01

Quantifying and predicting how submerged vegetation affects the velocity profile of riverine systems is crucial in ecohydraulics to properly assess the water quality and ecological functions or rivers. The state of the art includes a plethora of models to study the flow and transport over submerged canopies. However, most of them are validated against data collected in flume experiments with rigid cylinders. With the objective of investigating the capability of a simple analytical solution for vegetated flow to reproduce and predict the velocity profile of complex shaped flexible canopies, we use the flow model proposed by Battiato and Rubol [WRR 2013] as the analytical approximation of the mean velocity profile above and within the canopy layer. This model has the advantages (i) to threat the canopy layer as a porous medium, whose geometrical properties are associated with macroscopic effective permeability and (ii) to use input parameters that can be estimated by remote sensing techniques, such us the heights of the water level and the canopy. The analytical expressions for the average velocity profile and the discharge are tested against data collected across a wide range of canopy morphologies commonly encountered in riverine systems, such as grasses, woody vegetation and bushes. Results indicate good agreement between the analytical expressions and the data for both simple and complex plant geometry shapes. The rescaled low submergence velocities in the canopy layer followed the same scaling found in arrays of rigid cylinders. In addition, for the dataset analyzed, the Darcy friction factor scaled with the inverse of the bulk Reynolds number multiplied by the ratio of the fluid to turbulent viscosity.

Swiftly moving focus points and forming shapes through the scattering media

NASA Astrophysics Data System (ADS)

Tran, Vinh; Sahoo, Sujit Kumar; Tang, Dongliang; Dang, Cuong

2018-02-01

Propagation of light through scattering media such as ground glass or biological tissue limits the quality and intensity of focusing point. Wave front shaping technique which uses spatial light modulator (SLM) devices to reshape the field profile of incoming light, is considered as one of the most effective and convenient methods. Advanced biomedical or manufacturing applications require drawing various contours or shapes quickly and precisely. However, creating each shape behind the scattering medium needs different phase profiles, which are time consuming to optimize or measure. Here, we demonstrate a technique to draw various shapes or contours behind the scattering medium by swiftly moving the focus point without any mechanical movements. Our technique relies on the existence of speckle correlation property in scattering media, also known as optical memory effect. In our procedure, we first modulate the phase-only SLM to create the focus point on the other side of scattering medium. Then, we digitally shift the preoptimized phase profile on the SLM and ramp it to tilt the beam accordingly. Now, the incoming beam with identical phase profile shines on the same scattering region at a tilted angle to regenerate the focus point at the desired position due to memory effect. Moreover, with linear combination of different field patterns, we can generate a single phase profile on SLM to produce two, three or more focus points simultaneously on the other side of a turbid medium. Our method could provide a useful tool for prominent applications such as opto-genetic excitation, minimally invasive laser surgery and other related fields.

Characterization of a multi-axis ion chamber array.

PubMed

Simon, Thomas A; Kozelka, Jakub; Simon, William E; Kahler, Darren; Li, Jonathan; Liu, Chihray

2010-11-01

The aim of this work was to characterize a multi-axis ion chamber array (IC PROFILER; Sun Nuclear Corporation, Melbourne, FL, USA) that has the potential to simplify the acquisition of LINAC beam data. The IC PROFILER (or panel) measurement response was characterized with respect to radiation beam properties, including dose, dose per pulse, pulse rate frequency (PRF), and energy. Panel properties were also studied, including detector-calibration stability, power-on time, backscatter dependence, and the panel's agreement with water tank measurements [profiles, fractional depth dose (FDD), and output factors]. The panel's relative deviation was typically within (+/-) 1% of an independent (or nominal) response for all properties that were tested. Notable results were (a) a detectable relative field shape change of approximately 1% with linear accelerator PRF changes; (b) a large range in backscatter thickness had a minimal effect on the measured dose distribution (typically less than 1%); (c) the error spread in profile comparison between the panel and scanning water tank (Blue Phantom, CC13; IBA Schwarzenbruck, DE) was approximately (+/-) 0.75%. The ability of the panel to accurately reproduce water tank profiles, FDDs, and output factors is an indication of its abilities as a dosimetry system. The benefits of using the panel versus a scanning water tank are less setup time and less error susceptibility. The same measurements (including device setup and breakdown) for both systems took 180 min with the water tank versus 30 min with the panel. The time-savings increase as the measurement load is increased.

Correaltion of full-scale drag predictions with flight measurements on the C-141A aircraft. Phase 2: Wind tunnel test, analysis, and prediction techniques. Volume 1: Drag predictions, wind tunnel data analysis and correlation

NASA Technical Reports Server (NTRS)

Macwilkinson, D. G.; Blackerby, W. T.; Paterson, J. H.

1974-01-01

The degree of cruise drag correlation on the C-141A aircraft is determined between predictions based on wind tunnel test data, and flight test results. An analysis of wind tunnel tests on a 0.0275 scale model at Reynolds number up to 3.05 x 1 million/MAC is reported. Model support interference corrections are evaluated through a series of tests, and fully corrected model data are analyzed to provide details on model component interference factors. It is shown that predicted minimum profile drag for the complete configuration agrees within 0.75% of flight test data, using a wind tunnel extrapolation method based on flat plate skin friction and component shape factors. An alternative method of extrapolation, based on computed profile drag from a subsonic viscous theory, results in a prediction four percent lower than flight test data.

Reconstructing surface wave profiles from reflected acoustic pulses using multiple receivers.

PubMed

Walstead, Sean P; Deane, Grant B

2014-08-01

Surface wave shapes are determined by analyzing underwater reflected acoustic signals collected at multiple receivers. The transmitted signals are of nominal frequency 300 kHz and are reflected off surface gravity waves that are paddle-generated in a wave tank. An inverse processing algorithm reconstructs 50 surface wave shapes over a length span of 2.10 m. The inverse scheme uses a broadband forward scattering model based on Kirchhoff's diffraction formula to determine wave shapes. The surface reconstruction algorithm is self-starting in that source and receiver geometry and initial estimates of wave shape are determined from the same acoustic signals used in the inverse processing. A high speed camera provides ground-truth measurements of the surface wave field for comparison with the acoustically derived surface waves. Within Fresnel zone regions the statistical confidence of the inversely optimized surface profile exceeds that of the camera profile. Reconstructed surfaces are accurate to a resolution of about a quarter-wavelength of the acoustic pulse only within Fresnel zones associated with each source and receiver pair. Multiple isolated Fresnel zones from multiple receivers extend the spatial extent of accurate surface reconstruction while overlapping Fresnel zones increase confidence in the optimized profiles there.

Distributed Sensing and Shape Control of Piezoelectric Bimorph Mirrors

DOE Office of Scientific and Technical Information (OSTI.GOV)

Redmond, James M.; Barney, Patrick S.; Henson, Tammy D.

1999-07-28

As part of a collaborative effort between Sandia National Laboratories and the University of Kentucky to develop a deployable mirror for remote sensing applications, research in shape sensing and control algorithms that leverage the distributed nature of electron gun excitation for piezoelectric bimorph mirrors is summarized. A coarse shape sensing technique is developed that uses reflected light rays from the sample surface to provide discrete slope measurements. Estimates of surface profiles are obtained with a cubic spline curve fitting algorithm. Experiments on a PZT bimorph illustrate appropriate deformation trends as a function of excitation voltage. A parallel effort to effectmore » desired shape changes through electron gun excitation is also summarized. A one dimensional model-based algorithm is developed to correct profile errors in bimorph beams. A more useful two dimensional algorithm is also developed that relies on measured voltage-curvature sensitivities to provide corrective excitation profiles for the top and bottom surfaces of bimorph plates. The two algorithms are illustrated using finite element models of PZT bimorph structures subjected to arbitrary disturbances. Corrective excitation profiles that yield desired parabolic forms are computed, and are shown to provide the necessary corrective action.« less

Optical properties of mineral dust aerosol including analysis of particle size, composition, and shape effects, and the impact of physical and chemical processing

NASA Astrophysics Data System (ADS)

Alexander, Jennifer Mary

Atmospheric mineral dust has a large impact on the earth's radiation balance and climate. The radiative effects of mineral dust depend on factors including, particle size, shape, and composition which can all be extremely complex. Mineral dust particles are typically irregular in shape and can include sharp edges, voids, and fine scale surface roughness. Particle shape can also depend on the type of mineral and can vary as a function of particle size. In addition, atmospheric mineral dust is a complex mixture of different minerals as well as other, possibly organic, components that have been mixed in while these particles are suspended in the atmosphere. Aerosol optical properties are investigated in this work, including studies of the effect of particle size, shape, and composition on the infrared (IR) extinction and visible scattering properties in order to achieve more accurate modeling methods. Studies of particle shape effects on dust optical properties for single component mineral samples of silicate clay and diatomaceous earth are carried out here first. Experimental measurements are modeled using T-matrix theory in a uniform spheroid approximation. Previous efforts to simulate the measured optical properties of silicate clay, using models that assumed particle shape was independent of particle size, have achieved only limited success. However, a model which accounts for a correlation between particle size and shape for the silicate clays offers a large improvement over earlier modeling approaches. Diatomaceous earth is also studied as an example of a single component mineral dust aerosol with extreme particle shapes. A particle shape distribution, determined by fitting the experimental IR extinction data, used as a basis for modeling the visible light scattering properties. While the visible simulations show only modestly good agreement with the scattering data, the fits are generally better than those obtained using more commonly invoked particle shape distributions. The next goal of this work is to investigate if modeling methods developed in the studies of single mineral components can be generalized to predict the optical properties of more authentic aerosol samples which are complex mixtures of different minerals. Samples of Saharan sand, Iowa loess, and Arizona road dust are used here as test cases. T-matrix based simulations of the authentic samples, using measured particle size distributions, empirical mineralogies, and a priori particle shape models for each mineral component are directly compared with the measured IR extinction spectra and visible scattering profiles. This modeling approach offers a significant improvement over more commonly applied models that ignore variations in particle shape with size or mineralogy and include only a moderate range of shape parameters. Mineral dust samples processed with organic acids and humic material are also studied in order to explore how the optical properties of dust can change after being aged in the atmosphere. Processed samples include quartz mixed with humic material, and calcite reacted with acetic and oxalic acid. Clear differences in the light scattering properties are observed for all three processed mineral dust samples when compared to the unprocessed mineral dust or organic salt products. These interactions result in both internal and external mixtures depending on the sample. In addition, the presence of these organic materials can alter the mineral dust particle shape. Overall, however, these results demonstrate the need to account for the effects of atmospheric aging of mineral dust on aerosol optical properties. Particle shape can also affect the aerodynamic properties of mineral dust aerosol. In order to account for these effects, the dynamic shape factor is used to give a measure of particle asphericity. Dynamic shape factors of quartz are measured by mass and mobility selecting particles and measuring their vacuum aerodynamic diameter. From this, dynamic shape factors in both the transition and vacuum regime can be derived. The measured dynamic shape factors of quartz agree quite well with the spheroidal shape distributions derived through studies of the optical properties.

The effect of learning on bursting.

PubMed

Stegenga, Jan; Le Feber, Joost; Marani, Enrico; Rutten, Wim L C

2009-04-01

We have studied the effect that learning a new stimulus-response (SR) relationship had within a neuronal network cultured on a multielectrode array. For training, we applied repetitive focal electrical stimulation delivered at a low rate (<1/s). Stimulation was withdrawn when a desired SR success ratio was achieved. It has been shown elsewhere, and we verified that this training algorithm, named conditional repetitive stimulation (CRS), can be used to strengthen an initially weak SR. So far, it remained unclear what the role of the rest of the network during learning was. We therefore studied the effect of CRS on spontaneously occurring network bursts. To this end, we made profiles of the firing rates within network bursts. We have earlier shown that these profiles change shape on a time base of several hours during spontaneous development. We show here that profiles of summed activity, called burst profiles, changed shape at an increased rate during CRS. This suggests that the whole network was involved in making the changes necessary to incorporate the desired SR relationship. However, a local (path-specific) component to learning was also found by analyzing profiles of single-electrode-activity phase profiles. Phase profiles that were not part of the SR relationship changed far less during CRS than the phase profiles of the electrodes that were part of the SR relationship. Finally, the manner in which phase profiles changed shape varied and could not be linked to the SR relationship.

End-pumped Nd:YVO4 laser with reduced thermal lensing via the use of a ring-shaped pump beam.

PubMed

Lin, Di; Andrew Clarkson, W

2017-08-01

A simple approach for alleviating thermal lensing in end-pumped solid-state lasers using a pump beam with a ring-shaped intensity distribution to decrease the radial temperature gradient is described. This scheme has been implemented in a diode-end-pumped Nd:YVO 4 laser yielding 14 W of TEM 00 output at 1.064 μm with a corresponding slope efficiency of 53% and a beam propagation factor (M 2 ) of 1.08 limited by available pump power. By comparison, the same laser design with a conventional quasi-top-hat pump beam profile of approximately equal radial extent yielded only 9 W of output before the power rolled over due to thermal lensing. Further investigation with the aid of a probe beam revealed that the thermal lens power was ∼30% smaller for the ring-shaped pump beam compared to the quasi-top-hat beam. The implications for further power scaling in end-pumped laser configurations are considered.

Redox Control of Inflammation in Macrophages

PubMed Central

Dehne, Nathalie; Grossmann, Nina; Jung, Michaela; Namgaladze, Dmitry; Schmid, Tobias; von Knethen, Andreas; Weigert, Andreas

2013-01-01

Abstract Macrophages are present throughout the human body, constitute important immune effector cells, and have variable roles in a great number of pathological, but also physiological, settings. It is apparent that macrophages need to adjust their activation profile toward a steadily changing environment that requires altering their phenotype, a process known as macrophage polarization. Formation of reactive oxygen species (ROS), derived from NADPH-oxidases, mitochondria, or NO-producing enzymes, are not necessarily toxic, but rather compose a network signaling system, known as redox regulation. Formation of redox signals in classically versus alternatively activated macrophages, their action and interaction at the level of key targets, and the resulting physiology still are insufficiently understood. We review the identity, source, and biological activities of ROS produced during macrophage activation, and discuss how they shape the key transcriptional responses evoked by hypoxia-inducible transcription factors, nuclear-erythroid 2-p45-related factor 2 (Nrf2), and peroxisome proliferator-activated receptor-γ. We summarize the mechanisms how redox signals add to the process of macrophage polarization and reprogramming, how this is controlled by the interaction of macrophages with their environment, and addresses the outcome of the polarization process in health and disease. Future studies need to tackle the option whether we can use the knowledge of redox biology in macrophages to shape their mediator profile in pathophysiology, to accelerate healing in injured tissue, to fight the invading pathogens, or to eliminate settings of altered self in tumors. Antioxid. Redox Signal. 19, 595–637. PMID:23311665

Isolating Curvature Effects in Computing Wall-Bounded Turbulent Flows

NASA Technical Reports Server (NTRS)

Rumsey, Christopher L.; Gatski, Thomas B.

2001-01-01

The flow over the zero-pressure-gradient So-Mellor convex curved wall is simulated using the Navier-Stokes equations. An inviscid effective outer wall shape, undocumented in the experiment, is obtained by using an adjoint optimization method with the desired pressure distribution on the inner wall as the cost function. Using this wall shape with a Navier-Stokes method, the abilities of various turbulence models to simulate the effects of curvature without the complicating factor of streamwise pressure gradient can be evaluated. The one-equation Spalart-Allmaras turbulence model overpredicts eddy viscosity, and its boundary layer profiles are too full. A curvature-corrected version of this model improves results, which are sensitive to the choice of a particular constant. An explicit algebraic stress model does a reasonable job predicting this flow field. However, results can be slightly improved by modifying the assumption on anisotropy equilibrium in the model's derivation. The resulting curvature-corrected explicit algebraic stress model possesses no heuristic functions or additional constants. It lowers slightly the computed skin friction coefficient and the turbulent stress levels for this case (in better agreement with experiment), but the effect on computed velocity profiles is very small.

Profile of Secondary School Students with High Mathematics Ability in Solving Shape and Space Problem

ERIC Educational Resources Information Center

Putra, Mulia; Novita, Rita

2015-01-01

This study aimed to describe the profile of secondary school students with high mathematics ability in solving shape and space problem in PISA (Program for International Student Assessment). It is a descriptive research with a qualitative approach, in which the subjects in this study were students of class VIII SMP N 1 Banda Aceh. The results show…

Model equations for the Eiffel Tower profile: historical perspective and new results

NASA Astrophysics Data System (ADS)

Weidman, Patrick; Pinelis, Iosif

2004-07-01

Model equations for the shape of the Eiffel Tower are investigated. One model purported to be based on Eiffel's writing does not give a tower with the correct curvature. A second popular model not connected with Eiffel's writings provides a fair approximation to the tower's skyline profile of 29 contiguous panels. Reported here is a third model derived from Eiffel's concern about wind loads on the tower, as documented in his communication to the French Civil Engineering Society on 30 March 1885. The result is a nonlinear, integro-differential equation which is solved to yield an exponential tower profile. It is further verified that, as Eiffel wrote, "in reality the curve exterior of the tower reproduces, at a determined scale, the same curve of the moments produced by the wind". An analysis of the actual tower profile shows that it is composed of two piecewise continuous exponentials with different growth rates. This is explained by specific safety factors for wind loading that Eiffel & Company incorporated in the design of the free-standing tower. To cite this article: P. Weidman, I. Pinelis, C. R. Mecanique 332 (2004).

X-ray beam-shaping via deformable mirrors: surface profile and point spread function computation for Gaussian beams using physical optics.

PubMed

Spiga, D

2018-01-01

X-ray mirrors with high focusing performances are commonly used in different sectors of science, such as X-ray astronomy, medical imaging and synchrotron/free-electron laser beamlines. While deformations of the mirror profile may cause degradation of the focus sharpness, a deliberate deformation of the mirror can be made to endow the focus with a desired size and distribution, via piezo actuators. The resulting profile can be characterized with suitable metrology tools and correlated with the expected optical quality via a wavefront propagation code or, sometimes, predicted using geometric optics. In the latter case and for the special class of profile deformations with monotonically increasing derivative, i.e. concave upwards, the point spread function (PSF) can even be predicted analytically. Moreover, under these assumptions, the relation can also be reversed: from the desired PSF the required profile deformation can be computed analytically, avoiding the use of trial-and-error search codes. However, the computation has been so far limited to geometric optics, which entailed some limitations: for example, mirror diffraction effects and the size of the coherent X-ray source were not considered. In this paper, the beam-shaping formalism in the framework of physical optics is reviewed, in the limit of small light wavelengths and in the case of Gaussian intensity wavefronts. Some examples of shaped profiles are also shown, aiming at turning a Gaussian intensity distribution into a top-hat one, and checks of the shaping performances computing the at-wavelength PSF by means of the WISE code are made.

Investigation of the geometrical barrier in Bi-2212 using the magneto-optical technique

NASA Astrophysics Data System (ADS)

Lin, Z. W.; Gu, G. D.; Russell, G. J.

2000-08-01

It has been found that the penetration of vortices into a weak pinning crystal is governed by a geometrical barrier and they form a dome-shaped flux profile across the crystal. Using the powerful magneto-optical technique, we investigated this geometrical barrier in a high-purity Bi2Sr2CaCu2O8+x single-crystal platelet. Our results show that over the temperature range 20-70 K the dome-shaped profile is observed. Also, the influences of the edge shape and the roughness on the geometrical barrier are discussed.

Analyzing gene expression time-courses based on multi-resolution shape mixture model.

PubMed

Li, Ying; He, Ye; Zhang, Yu

2016-11-01

Biological processes actually are a dynamic molecular process over time. Time course gene expression experiments provide opportunities to explore patterns of gene expression change over a time and understand the dynamic behavior of gene expression, which is crucial for study on development and progression of biology and disease. Analysis of the gene expression time-course profiles has not been fully exploited so far. It is still a challenge problem. We propose a novel shape-based mixture model clustering method for gene expression time-course profiles to explore the significant gene groups. Based on multi-resolution fractal features and mixture clustering model, we proposed a multi-resolution shape mixture model algorithm. Multi-resolution fractal features is computed by wavelet decomposition, which explore patterns of change over time of gene expression at different resolution. Our proposed multi-resolution shape mixture model algorithm is a probabilistic framework which offers a more natural and robust way of clustering time-course gene expression. We assessed the performance of our proposed algorithm using yeast time-course gene expression profiles compared with several popular clustering methods for gene expression profiles. The grouped genes identified by different methods are evaluated by enrichment analysis of biological pathways and known protein-protein interactions from experiment evidence. The grouped genes identified by our proposed algorithm have more strong biological significance. A novel multi-resolution shape mixture model algorithm based on multi-resolution fractal features is proposed. Our proposed model provides a novel horizons and an alternative tool for visualization and analysis of time-course gene expression profiles. The R and Matlab program is available upon the request. Copyright © 2016 Elsevier Inc. All rights reserved.

Beam shaping in high-power laser systems with using refractive beam shapers

NASA Astrophysics Data System (ADS)

Laskin, Alexander; Laskin, Vadim

2012-06-01

Beam Shaping of the spatial (transverse) profile of laser beams is highly desirable by building optical systems of high-power lasers as well in various applications with these lasers. Pumping of the crystals of Ti:Sapphire lasers by the laser radiation with uniform (flattop) intensity profile improves performance of these ultrashort pulse high-power lasers in terms of achievable efficiency, peak-power and stability, output beam profile. Specifications of the solid-state lasers built according to MOPA configuration can be also improved when radiation of the master oscillator is homogenized and then is amplified by the power amplifier. Features of building these high power lasers require that a beam shaping solution should be capable to work with single mode and multimode beams, provide flattop and super-Gauss intensity distributions, the consistency and divergence of a beam after the intensity re-distribution should be conserved and low absorption provided. These specific conditions are perfectly fulfilled by the refractive field mapping beam shapers due to their unique features: almost lossless intensity profile transformation, low output divergence, high transmittance and flatness of output beam profile, extended depth of field, adaptability to real intensity profiles of TEM00 and multimode laser sources. Combining of the refractive field mapping beam shapers with other optical components, like beam-expanders, relay imaging lenses, anamorphic optics makes it possible to generate the laser spots of necessary shape, size and intensity distribution. There are plenty of applications of high-power lasers where beam shaping bring benefits: irradiating photocathode of Free Electron Lasers (FEL), material ablation, micromachining, annealing in display making techniques, cladding, heat treating and others. This paper will describe some design basics of refractive beam shapers of the field mapping type, with emphasis on the features important for building and applications of high-power laser sources. There will be presented results of applying the refractive beam shapers in real installations.

Volatile-rich Crater Interior Deposits in the Polar Regions of Mars: Evidence for Ice Cap Advance and Retreat

NASA Technical Reports Server (NTRS)

Russell, Patrick S.; Head, James W.; Hecht, Michael H.

2003-01-01

Many craters on Mars are partially filled by distinctive material emplaced by post-impact processes. This crater fill material is an interior mound which is generally separated from the walls of the crater by a trough that may be continuous along the crater circumference (i.e. a ring-shaped trough), or which may only partially contact the crater walls (i.e. a crescent-shaped trough). The fill deposit is frequently offset from the crater center and may be asymmetric in plan view. Populations of such craters include those in the circum-south polar cap region, in Arabia Terra, associated with the Medusae Fossae Formation, and in the northern lowlands proximal to the north polar cap. We focus on those craters in circumpolar regions and assess their relationship to polar cap advance and retreat, especially the possibility that fill material represents remnants of a formerly larger contiguous cap. Volatile-rich deposits have the property of being modifiable by the local stability of the solid volatile, which is governed by local energy balance. Here we test the hypothesis that asymmetries in volatile fill shape, profile, and center-location within a crater result from asymmetries in local energy balance within the crater, due mainly to variation of solar insolation and radiative effects of the crater walls over the crater interior. Model profiles of crater fill are compared with MOLA topographic profiles to assess this hypothesis. If asymmetry in morphology and location of crater fill are consistent with radiative-dominated asymmetries in energy budget within the crater, then 1) the volatile-rich composition of the fill is supported (this process should not be effective at shaping volcanic or sedimentary deposits), and 2) the dominant factor determining the observed shape of volatile-rich crater fill is the local radiative energy budget (and erosive processes such as eolian deflation are secondary or unnecessary). We also use a geographic and energy model approach to specifically test the idea that material in partially filled craters around the south pole may once have been contiguous to the cap and may have been sustained and modified by radiative processes specific to the crater environment (as opposed to the surrounding plains) as the cap retreated.

The confining baryonic Y-strings on the lattice

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bakry, Ahmed S.; Chen, Xurong; Zhang, Peng-Ming

2016-01-22

In a string picture, the nucleon is conjectured as consisting of a Y-shaped gluonic string ended by constituent quarks. In this proceeding, we summarize our results on revealing the signature of the confining Y-bosonic string in the gluonic profile due to a system of three static quarks on the lattice at finite temperature. The analysis of the action density unveils a background of a filled-Δ distribution. However, we found that these Δ-shaped profiles are comprised of three Y-shaped Gaussian-like flux tubes. The length of the revealed Y-string-like distribution is maximum near the deconfinement point and approaches the geometrical minimal nearmore » the end of the QCD plateau. The action density width profile returns good fits to a baryonic string model for the junction fluctuations at large quark source separation.« less

Shaping ability of ProFile.04 Taper Series 29 rotary nickel-titanium instruments in simulated root canals. Part 1.

PubMed

Thompson, S A; Dummer, P M

1997-01-01

The aim of this study was to determine the shaping ability of ProFile.04 Taper Series 29 nickel-titanium instruments in simulated canals. A total of 40 simulated root canals made up of four different shapes in terms of angle and position of curvature were prepared by ProFile instruments using a step-down approach. Part 1 of this two-part report describes the efficacy of the instruments in terms of preparation time, instrument failure, canal blockages, loss of canal length and three-dimensional canal form. The time necessary for canal preparation was not influenced significantly by canal shape. No instrument fractures occurred but a total of 52 instruments deformed. Size 6 instruments deformed the most followed by sizes 5, 3 and 4. Canal shape did not influence significantly instrument deformation. None of the canals became blocked with debris and loss of working distance was on average 0.5 mm or less. Intracanal impressions of canal form demonstrated that most canals had definite apical stops, smooth canal walls and good flow and taper. Under the conditions of this study, ProFile.04 Taper Series 29 rotary nickel-titanium instruments prepared simulated canals rapidly and created good three-dimensional form. A substantial number of instruments deformed but it was not possible to determine whether this phenomenon occurred because of the nature of the experimental model or through an inherent design weakness in the instruments.

Overloaded elution band profiles of ionizable compounds in reversed-phase liquid chromatography: Influence of the competition between the neutral and the ionic species

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gritti, Fabrice; Guiochon, Georges A

2008-01-01

The parameters that affect the shape of the band profiles of acido-basic compounds under moderately overloaded conditions (sample size less than 500 nmol for a conventional column) in RPLC are discussed. Only analytes that have a single pK{sub a} are considered. In the buffer mobile phase used for their elution, their dissociation may, under certain conditions, cause a significant pH perturbation during the passage of the band. Two consecutive injections (3.3 and 10 {micro}L) of each one of three sample solutions (0.5, 5, and 50 mM) of ten compounds were injected on five C{sub 18}-bonded packing materials, including the 5more » {micro}m Xterra-C{sub 18} (121 {angstrom}), 5 {micro}m Gemini-C{sub 18} (110 {angstrom}), 5 {micro}m Luna-C{sub 18}(2) (93 {angstrom}), 3.5 {micro}m Extend-C{sub 18} (80 {angstrom}), and 2.7 {micro}m Halo-C{sub 18} (90 {angstrom}). The mobile phase was an aqueous solution of methanol buffered at a constant {sub W}{sup W}pH of 6, with a phosphate buffer. The total concentration of the phosphate groups was constant at 50 mM. The methanol concentration was adjusted to keep all the retention factors between 1 and 10. The compounds injected were phenol, caffeine, 3-phenyl 1-propanol, 2-phenyl butyric acid, amphetamine, aniline, benzylamine, p-toluidine, procainamidium chloride, and propranololium chloride. Depending on the relative values of the analyte pK{sub a} and the buffer solution pH, these analytes elute as the neutral, the cationic, or the anionic species. The influence of structural parameters such as the charge, the size, and the hydrophobicity of the analytes on the shape of its overloaded band profile is discussed. Simple but general rules predict these shapes. An original adsorption model is proposed that accounts for the unusual peak shapes observed when the analyte is partially dissociated in the buffer solution during its elution.« less

Numerical modeling of field-assisted ion-exchanged channel waveguides by the explicit consideration of space-charge buildup.

PubMed

Mrozek, Piotr

2011-08-01

A numerical model explicitly considering the space-charge density evolved both under the mask and in the region of optical structure formation was used to predict the profiles of Ag concentration during field-assisted Ag(+)-Na(+) ion exchange channel waveguide fabrication. The influence of the unequal values of diffusion constants and mobilities of incoming and outgoing ions, the value of a correlation factor (Haven ratio), and particularly space-charge density induced during the ion exchange, on the resulting profiles of Ag concentration was analyzed and discussed. It was shown that the incorporation into the numerical model of a small quantity of highly mobile ions other than exclusively Ag(+) and Na(+) may considerably affect the range and shape of calculated Ag profiles in the multicomponent glass. The Poisson equation was used to predict the electric field spread evolution in the glass substrate. The results of the numerical analysis were verified by the experimental data of Ag concentration in a channel waveguide fabricated using a field-assisted process.

SIMS of Organic Materials—Interface Location in Argon Gas Cluster Depth Profiles Using Negative Secondary Ions

NASA Astrophysics Data System (ADS)

Havelund, R.; Seah, M. P.; Tiddia, M.; Gilmore, I. S.

2018-02-01

A procedure has been established to define the interface position in depth profiles accurately when using secondary ion mass spectrometry and the negative secondary ions. The interface position varies strongly with the extent of the matrix effect and so depends on the secondary ion measured. Intensity profiles have been measured at both fluorenylmethyloxycarbonyl-uc(l)-pentafluorophenylalanine (FMOC) to Irganox 1010 and Irganox 1010 to FMOC interfaces for many secondary ions. These profiles show separations of the two interfaces that vary over some 10 nm depending on the secondary ion selected. The shapes of these profiles are strongly governed by matrix effects, slightly weakened by a long wavelength roughening. The matrix effects are separately measured using homogeneous, known mixtures of these two materials. Removal of the matrix and roughening effects give consistent compositional profiles for all ions that are described by an integrated exponentially modified Gaussian (EMG) profile. Use of a simple integrated Gaussian may lead to significant errors. The average interface positions in the compositional profiles are determined to standard uncertainties of 0.19 and 0.14 nm, respectively, using the integrated EMG function. Alternatively, and more simply, it is shown that interface positions and profiles may be deduced from data for several secondary ions with measured matrix factors by simply extrapolating the result to Ξ = 0. Care must be taken in quoting interface resolutions since those measured for predominantly Gaussian interfaces with Ξ above or below zero, without correction, appear significantly better than the true resolution.

Analysis of castellated steel beam with oval openings

NASA Astrophysics Data System (ADS)

Tudjono, S.; Sunarto; Han, A. L.

2017-11-01

A castellated steel beam is per definition a wide flange (WF) or I shaped steel profile with openings, to reduce self-weight and improve the effectiveness in terms of material use. Recently, extensive study on these castellated steel beams has been conducted, involving different shapes in web openings. The main goal of these research works was to evaluate and analyze its optimum opening sizes and shapes configuration. More in-depth research work to the behavior and the influence of holes to WF beams need to be conducted. In this paper, an oval shaped web opening is chosen as alternate. The study involves a modification in the variation of oval web openings both in the horizontally and vertically direction. An experimental and numerical study based on the finite element method conducted with the Abaqus/CAE 6.12 software is used to analyze the buckling behavior of the web. The obtained results from the experimental test specimens are in good agreement with the obtained results from the finite element analysis. Furthermore, the numerical model can be expanded to be used as analyzing tool in evaluating and studying the effect and influencing factors of a variation in opening’s parameters.

Tracking and shape errors measurement of concentrating heliostats

NASA Astrophysics Data System (ADS)

Coquand, Mathieu; Caliot, Cyril; Hénault, François

2017-09-01

In solar tower power plants, factors such as tracking accuracy, facets misalignment and surface shape errors of concentrating heliostats are of prime importance on the efficiency of the system. At industrial scale, one critical issue is the time and effort required to adjust the different mirrors of the faceted heliostats, which could take several months using current techniques. Thus, methods enabling quick adjustment of a field with a huge number of heliostats are essential for the rise of solar tower technology. In this communication is described a new method for heliostat characterization that makes use of four cameras located near the solar receiver and simultaneously recording images of the sun reflected by the optical surfaces. From knowledge of a measured sun profile, data processing of the acquired images allows reconstructing the slope and shape errors of the heliostats, including tracking and canting errors. The mathematical basis of this shape reconstruction process is explained comprehensively. Numerical simulations demonstrate that the measurement accuracy of this "backward-gazing method" is compliant with the requirements of solar concentrating optics. Finally, we present our first experimental results obtained at the THEMIS experimental solar tower plant in Targasonne, France.

The non-small cell lung cancer immune landscape: emerging complexity, prognostic relevance and prospective significance in the context of immunotherapy.

PubMed

Anichini, Andrea; Tassi, Elena; Grazia, Giulia; Mortarini, Roberta

2018-06-01

Immunotherapy of non-small cell lung cancer (NSCLC), by immune checkpoint inhibitors, has profoundly improved the clinical management of advanced disease. However, only a fraction of patients respond and no effective predictive factors have been defined. Here, we discuss the prospects for identification of such predictors of response to immunotherapy, by fostering an in-depth analysis of the immune landscape of NSCLC. The emerging picture, from several recent studies, is that the immune contexture of NSCLC lesions is a complex and heterogeneous feature, as documented by analysis for frequency, phenotype and spatial distribution of innate and adaptive immune cells, and by characterization of functional status of inhibitory receptor + T cells. The complexity of the immune landscape of NSCLC stems from the interaction of several factors, including tumor histology, molecular subtype, main oncogenic drivers, nonsynonymous mutational load, tumor aneuploidy, clonal heterogeneity and tumor evolution, as well as the process of epithelial-mesenchymal transition. All these factors contribute to shape NSCLC immune profiles that have clear prognostic significance. An integrated analysis of the immune and molecular profile of the neoplastic lesions may allow to define the potential predictive role of the immune landscape for response to immunotherapy.

Effect of masking phase-only holograms on the quality of reconstructed images.

PubMed

Deng, Yuanbo; Chu, Daping

2016-04-20

A phase-only hologram modulates the phase of the incident light and diffracts it efficiently with low energy loss because of the minimum absorption. Much research attention has been focused on how to generate phase-only holograms, and little work has been done to understand the effect and limitation of their partial implementation, possibly due to physical defects and constraints, in particular as in the practical situations where a phase-only hologram is confined or needs to be sliced or tiled. The present study simulates the effect of masking phase-only holograms on the quality of reconstructed images in three different scenarios with different filling factors, filling positions, and illumination intensity profiles. Quantitative analysis confirms that the width of the image point spread function becomes wider and the image quality decreases, as expected, when the filling factor decreases, and the image quality remains the same for different filling positions as well. The width of the image point spread function as derived from different filling factors shows a consistent behavior to that as measured directly from the reconstructed image, especially as the filling factor becomes small. Finally, mask profiles of different shapes and intensity distributions are shown to have more complicated effects on the image point spread function, which in turn affects the quality and textures of the reconstructed image.

Computation of stress on the surface of a soft homogeneous arbitrarily shaped particle.

PubMed

Yang, Minglin; Ren, Kuan Fang; Wu, Yueqian; Sheng, Xinqing

2014-04-01

Prediction of the stress on the surface of an arbitrarily shaped particle of soft material is essential in the study of elastic properties of the particles with optical force. It is also necessary in the manipulation and sorting of small particles with optical tweezers, since a regular-shaped particle, such as a sphere, may be deformed under the nonuniform optical stress on its surface. The stress profile on a spherical or small spheroidal soft particle trapped by shaped beams has been studied, however little work on computing the surface stress of an irregular-shaped particle has been reported. We apply in this paper the surface integral equation with multilevel fast multipole algorithm to compute the surface stress on soft homogeneous arbitrarily shaped particles. The comparison of the computed stress profile with that predicted by the generalized Lorenz-Mie theory for a water droplet of diameter equal to 51 wavelengths in a focused Gaussian beam show that the precision of our method is very good. Then stress profiles on spheroids with different aspect ratios are computed. The particles are illuminated by a Gaussian beam of different waist radius at different incidences. Physical analysis on the mechanism of optical stress is given with help of our recently developed vectorial complex ray model. It is found that the maximum of the stress profile on the surface of prolate spheroids is not only determined by the reflected and refracted rays (orders p=0,1) but also the rays undergoing one or two internal reflections where they focus. Computational study of stress on surface of a biconcave cell-like particle, which is a typical application in life science, is also undertaken.

Label-Free Quantitation of Ribosomal Proteins from Bacillus subtilis for Antibiotic Research.

PubMed

Schäkermann, Sina; Prochnow, Pascal; Bandow, Julia E

2017-01-01

Current research is focusing on ribosome heterogeneity as a response to changing environmental conditions and stresses, such as antibiotic stress. Altered stoichiometry and composition of ribosomal proteins as well as association of additional protein factors are mechanisms for shaping the protein expression profile or hibernating ribosomes. Here, we present a method for the isolation of ribosomes to analyze antibiotic-induced changes in the composition of ribosomes in Bacillus subtilis or other bacteria. Ribosomes and associated proteins are isolated by ultracentrifugation and proteins are identified and quantified using label-free mass spectrometry.

Compilation of Information on the Transonic Attachment of Flows at the Leading Edges of Airfoils

NASA Technical Reports Server (NTRS)

Lindsey, Walter F; Landrum, Emma Jean

1958-01-01

Schlieren photographs have been compiled of the two-dimensional flow at transonic speeds past 37 airfoils. These airfoils have variously shaped profiles, and some are related in thickness and camber. The data for these airfoils were analyzed to provide basic information on the flow changes involved and to determine factors affecting transonic-flow attachment, which is a transition from separated to unseparated flow at the leading edges of two-dimensional airfoils at fixed angles as the subsonic Mach number is increased.

3D shape measurements with a single interferometric sensor for in-situ lathe monitoring

NASA Astrophysics Data System (ADS)

Kuschmierz, R.; Huang, Y.; Czarske, J.; Metschke, S.; Löffler, F.; Fischer, A.

2015-05-01

Temperature drifts, tool deterioration, unknown vibrations as well as spindle play are major effects which decrease the achievable precision of computerized numerically controlled (CNC) lathes and lead to shape deviations between the processed work pieces. Since currently no measurement system exist for fast, precise and in-situ 3d shape monitoring with keyhole access, much effort has to be made to simulate and compensate these effects. Therefore we introduce an optical interferometric sensor for absolute 3d shape measurements, which was integrated into a working lathe. According to the spindle rotational speed, a measurement rate of 2,500 Hz was achieved. In-situ absolute shape, surface profile and vibration measurements are presented. While thermal drifts of the sensor led to errors of several mµm for the absolute shape, reference measurements with a coordinate machine show, that the surface profile could be measured with an uncertainty below one micron. Additionally, the spindle play of 0.8 µm was measured with the sensor.

Simulated gamma-ray pulse profile of the Crab pulsar with the Cherenkov Telescope Array

NASA Astrophysics Data System (ADS)

Burtovoi, A.; Zampieri, L.

2016-07-01

We present simulations of the very high energy (VHE) gamma-ray light curve of the Crab pulsar as observed by the Cherenkov Telescope Array (CTA). The CTA pulse profile of the Crab pulsar is simulated with the specific goal of determining the accuracy of the position of the interpulse. We fit the pulse shape obtained by the Major Atmospheric Gamma-Ray Imaging Cherenkov (MAGIC) telescope with a three-Gaussian template and rescale it to account for the different CTA instrumental and observational configurations. Simulations are performed for different configurations of CTA and for the ASTRI (Astrofisica con Specchi a Tecnologia Replicante Italiana) mini-array. The northern CTA configuration will provide an improvement of a factor of ˜3 in accuracy with an observing time comparable to that of MAGIC (73 h). Unless the VHE spectrum above 1 TeV behaves differently from what we presently know, unreasonably long observing times are required for a significant detection of the pulsations of the Crab pulsar with the high-energy-range sub-arrays. We also found that an independent VHE timing analysis is feasible with Large Size Telescopes. CTA will provide a significant improvement in determining the VHE pulse shape parameters necessary to constrain theoretical models of the gamma-ray emission of the Crab pulsar. One of such parameters is the shift in phase between peaks in the pulse profile at VHE and in other energy bands that, if detected, may point to different locations of the emission regions.

Profiles of Adolescents' Perceptions of Democratic Classroom Climate and Students' Influence: The Effect of School and Community Contexts.

PubMed

Reichert, Frank; Chen, Jiaxin; Torney-Purta, Judith

2018-06-01

Students' learning experiences and outcomes are shaped by school and classroom contexts. Many studies have shown how an open, democratic classroom climate relates to learning in the citizenship domain and helps nurture active and engaged citizens. However, little research has been undertaken to look at how such a favorable classroom climate may work together with broader school factors. The current study examines data from 14,292 Nordic eighth graders (51% female) who had participated in the International Civic and Citizenship Education Study in 2009, as well as contextual data from 5,657 teachers and 618 principals. Latent class analysis identifies profiles of students' perceptions of school context, which are further examined with respect to the contextual correlates at the school level using two-level fixed effects multinomial regression analyses. Five distinct student profiles are identified and labeled "alienated", "indifferent", "activist", "debater", and "communitarian". Compared to indifferent students, debaters and activists appear more frequently at schools with relatively few social problems; being in the communitarian group is associated with aspects of the wider community. Furthermore, being in one of these three groups (and not in the indifferent group) is more likely when teachers act as role models by engaging in school governance. The results are discussed within the framework of ecological assets and developmental niches for emergent participatory citizenship. The implications are that adults at school could enhance multiple contexts that shape adolescents' developmental niches to nurture active and informed citizens for democracies.

Characterization of a multi-axis ion chamber array

DOE Office of Scientific and Technical Information (OSTI.GOV)

Simon, Thomas A.; Kozelka, Jakub; Simon, William E.

Purpose: The aim of this work was to characterize a multi-axis ion chamber array (IC PROFILER; Sun Nuclear Corporation, Melbourne, FL USA) that has the potential to simplify the acquisition of LINAC beam data. Methods: The IC PROFILER (or panel) measurement response was characterized with respect to radiation beam properties, including dose, dose per pulse, pulse rate frequency (PRF), and energy. Panel properties were also studied, including detector-calibration stability, power-on time, backscatter dependence, and the panel's agreement with water tank measurements [profiles, fractional depth dose (FDD), and output factors]. Results: The panel's relative deviation was typically within ({+-}) 1% ofmore » an independent (or nominal) response for all properties that were tested. Notable results were (a) a detectable relative field shape change of {approx}1% with linear accelerator PRF changes; (b) a large range in backscatter thickness had a minimal effect on the measured dose distribution (typically less than 1%); (c) the error spread in profile comparison between the panel and scanning water tank (Blue Phantom, CC13; IBA Schwarzenbruck, DE) was approximately ({+-}) 0.75%. Conclusions: The ability of the panel to accurately reproduce water tank profiles, FDDs, and output factors is an indication of its abilities as a dosimetry system. The benefits of using the panel versus a scanning water tank are less setup time and less error susceptibility. The same measurements (including device setup and breakdown) for both systems took 180 min with the water tank versus 30 min with the panel. The time-savings increase as the measurement load is increased.« less

A high-resolution and observationally constrained OMI NO 2 satellite retrieval

DOE Office of Scientific and Technical Information (OSTI.GOV)

Goldberg, Daniel L.; Lamsal, Lok N.; Loughner, Christopher P.

Here, this work presents a new high-resolution NO 2 dataset derived from the NASA Ozone Monitoring Instrument (OMI) NO 2 version 3.0 retrieval that can be used to estimate surface-level concentrations. The standard NASA product uses NO 2 vertical profile shape factors from a 1.25° × 1° (~110 km × 110 km) resolution Global Model Initiative (GMI) model simulation to calculate air mass factors, a critical value used to determine observed tropospheric NO 2 vertical columns. To better estimate vertical profile shape factors, we use a high-resolution (1.33 km × 1.33 km) Community Multi-scale Air Quality (CMAQ) model simulation constrained by in situmore » aircraft observations to recalculate tropospheric air mass factors and tropospheric NO 2 vertical columns during summertime in the eastern US. In this new product, OMI NO 2 tropospheric columns increase by up to 160% in city centers and decrease by 20–50 % in the rural areas outside of urban areas when compared to the operational NASA product. Our new product shows much better agreement with the Pandora NO 2 and Airborne Compact Atmospheric Mapper (ACAM) NO 2 spectrometer measurements acquired during the DISCOVER-AQ Maryland field campaign. Furthermore, the correlation between our satellite product and EPA NO 2 monitors in urban areas has improved dramatically: r 2 = 0.60 in the new product vs. r 2 = 0.39 in the operational product, signifying that this new product is a better indicator of surface concentrations than the operational product. Our work emphasizes the need to use both high-resolution and high-fidelity models in order to recalculate satellite data in areas with large spatial heterogeneities in NO x emissions. Although the current work is focused on the eastern US, the methodology developed in this work can be applied to other world regions to produce high-quality region-specific NO 2 satellite retrievals.« less

A high-resolution and observationally constrained OMI NO 2 satellite retrieval

DOE PAGES

Goldberg, Daniel L.; Lamsal, Lok N.; Loughner, Christopher P.; ...

2017-09-26

Here, this work presents a new high-resolution NO 2 dataset derived from the NASA Ozone Monitoring Instrument (OMI) NO 2 version 3.0 retrieval that can be used to estimate surface-level concentrations. The standard NASA product uses NO 2 vertical profile shape factors from a 1.25° × 1° (~110 km × 110 km) resolution Global Model Initiative (GMI) model simulation to calculate air mass factors, a critical value used to determine observed tropospheric NO 2 vertical columns. To better estimate vertical profile shape factors, we use a high-resolution (1.33 km × 1.33 km) Community Multi-scale Air Quality (CMAQ) model simulation constrained by in situmore » aircraft observations to recalculate tropospheric air mass factors and tropospheric NO 2 vertical columns during summertime in the eastern US. In this new product, OMI NO 2 tropospheric columns increase by up to 160% in city centers and decrease by 20–50 % in the rural areas outside of urban areas when compared to the operational NASA product. Our new product shows much better agreement with the Pandora NO 2 and Airborne Compact Atmospheric Mapper (ACAM) NO 2 spectrometer measurements acquired during the DISCOVER-AQ Maryland field campaign. Furthermore, the correlation between our satellite product and EPA NO 2 monitors in urban areas has improved dramatically: r 2 = 0.60 in the new product vs. r 2 = 0.39 in the operational product, signifying that this new product is a better indicator of surface concentrations than the operational product. Our work emphasizes the need to use both high-resolution and high-fidelity models in order to recalculate satellite data in areas with large spatial heterogeneities in NO x emissions. Although the current work is focused on the eastern US, the methodology developed in this work can be applied to other world regions to produce high-quality region-specific NO 2 satellite retrievals.« less

A high-resolution and observationally constrained OMI NO2 satellite retrieval

NASA Astrophysics Data System (ADS)

Goldberg, Daniel L.; Lamsal, Lok N.; Loughner, Christopher P.; Swartz, William H.; Lu, Zifeng; Streets, David G.

2017-09-01

This work presents a new high-resolution NO2 dataset derived from the NASA Ozone Monitoring Instrument (OMI) NO2 version 3.0 retrieval that can be used to estimate surface-level concentrations. The standard NASA product uses NO2 vertical profile shape factors from a 1.25° × 1° (˜ 110 km × 110 km) resolution Global Model Initiative (GMI) model simulation to calculate air mass factors, a critical value used to determine observed tropospheric NO2 vertical columns. To better estimate vertical profile shape factors, we use a high-resolution (1.33 km × 1.33 km) Community Multi-scale Air Quality (CMAQ) model simulation constrained by in situ aircraft observations to recalculate tropospheric air mass factors and tropospheric NO2 vertical columns during summertime in the eastern US. In this new product, OMI NO2 tropospheric columns increase by up to 160 % in city centers and decrease by 20-50 % in the rural areas outside of urban areas when compared to the operational NASA product. Our new product shows much better agreement with the Pandora NO2 and Airborne Compact Atmospheric Mapper (ACAM) NO2 spectrometer measurements acquired during the DISCOVER-AQ Maryland field campaign. Furthermore, the correlation between our satellite product and EPA NO2 monitors in urban areas has improved dramatically: r2 = 0.60 in the new product vs. r2 = 0.39 in the operational product, signifying that this new product is a better indicator of surface concentrations than the operational product. Our work emphasizes the need to use both high-resolution and high-fidelity models in order to recalculate satellite data in areas with large spatial heterogeneities in NOx emissions. Although the current work is focused on the eastern US, the methodology developed in this work can be applied to other world regions to produce high-quality region-specific NO2 satellite retrievals.

New fast least-squares algorithm for estimating the best-fitting parameters due to simple geometric-structures from gravity anomalies.

PubMed

Essa, Khalid S

2014-01-01

A new fast least-squares method is developed to estimate the shape factor (q-parameter) of a buried structure using normalized residual anomalies obtained from gravity data. The problem of shape factor estimation is transformed into a problem of finding a solution of a non-linear equation of the form f(q) = 0 by defining the anomaly value at the origin and at different points on the profile (N-value). Procedures are also formulated to estimate the depth (z-parameter) and the amplitude coefficient (A-parameter) of the buried structure. The method is simple and rapid for estimating parameters that produced gravity anomalies. This technique is used for a class of geometrically simple anomalous bodies, including the semi-infinite vertical cylinder, the infinitely long horizontal cylinder, and the sphere. The technique is tested and verified on theoretical models with and without random errors. It is also successfully applied to real data sets from Senegal and India, and the inverted-parameters are in good agreement with the known actual values.

New fast least-squares algorithm for estimating the best-fitting parameters due to simple geometric-structures from gravity anomalies

PubMed Central

Essa, Khalid S.

2013-01-01

A new fast least-squares method is developed to estimate the shape factor (q-parameter) of a buried structure using normalized residual anomalies obtained from gravity data. The problem of shape factor estimation is transformed into a problem of finding a solution of a non-linear equation of the form f(q) = 0 by defining the anomaly value at the origin and at different points on the profile (N-value). Procedures are also formulated to estimate the depth (z-parameter) and the amplitude coefficient (A-parameter) of the buried structure. The method is simple and rapid for estimating parameters that produced gravity anomalies. This technique is used for a class of geometrically simple anomalous bodies, including the semi-infinite vertical cylinder, the infinitely long horizontal cylinder, and the sphere. The technique is tested and verified on theoretical models with and without random errors. It is also successfully applied to real data sets from Senegal and India, and the inverted-parameters are in good agreement with the known actual values. PMID:25685472

Ultraviolet laser transverse profile shaping for improving x-ray free electron laser performance

DOE PAGES

Li, S.; Alverson, S.; Bohler, D.; ...

2017-08-17

The photocathode rf gun is one of the most critical components in x-ray free electron lasers. The drive laser strikes the photocathode surface, which emits electrons with properties that depend on the shape of the drive laser. Most free electron lasers use photocathodes with work function in the ultraviolet, a wavelength where direct laser manipulation becomes challenging. In this paper, we present a novel application of a digital micromirror device (DMD) for the 253 nm drive laser at the Linear Coherent Light Source. Laser profile shaping is accomplished through an iterative algorithm that takes into account shaping error and efficiency.more » Next, we use laser shaping to control the X-ray laser output via an online optimizer, which shows improvement in FEL pulse energy. Lastly, as a preparation for electron beam shaping, we use the DMD to measure the photocathode quantum efficiency across cathode surface with an averaged laser rms spot size of 59 μm. In conclusion, our experiments demonstrate promising outlook of using DMD to shape ultraviolet lasers for photocathode rf guns with various applications.« less

Ultraviolet laser transverse profile shaping for improving x-ray free electron laser performance

DOE Office of Scientific and Technical Information (OSTI.GOV)

Li, S.; Alverson, S.; Bohler, D.

The photocathode rf gun is one of the most critical components in x-ray free electron lasers. The drive laser strikes the photocathode surface, which emits electrons with properties that depend on the shape of the drive laser. Most free electron lasers use photocathodes with work function in the ultraviolet, a wavelength where direct laser manipulation becomes challenging. In this paper, we present a novel application of a digital micromirror device (DMD) for the 253 nm drive laser at the Linear Coherent Light Source. Laser profile shaping is accomplished through an iterative algorithm that takes into account shaping error and efficiency.more » Next, we use laser shaping to control the X-ray laser output via an online optimizer, which shows improvement in FEL pulse energy. Lastly, as a preparation for electron beam shaping, we use the DMD to measure the photocathode quantum efficiency across cathode surface with an averaged laser rms spot size of 59 μm. In conclusion, our experiments demonstrate promising outlook of using DMD to shape ultraviolet lasers for photocathode rf guns with various applications.« less

Ultraviolet laser transverse profile shaping for improving x-ray free electron laser performance

NASA Astrophysics Data System (ADS)

Li, S.; Alverson, S.; Bohler, D.; Egger, A.; Fry, A.; Gilevich, S.; Huang, Z.; Miahnahri, A.; Ratner, D.; Robinson, J.; Zhou, F.

2017-08-01

The photocathode rf gun is one of the most critical components in x-ray free electron lasers. The drive laser strikes the photocathode surface, which emits electrons with properties that depend on the shape of the drive laser. Most free electron lasers use photocathodes with work function in the ultraviolet, a wavelength where direct laser manipulation becomes challenging. In this paper, we present a novel application of a digital micromirror device (DMD) for the 253 nm drive laser at the Linear Coherent Light Source. Laser profile shaping is accomplished through an iterative algorithm that takes into account shaping error and efficiency. Next, we use laser shaping to control the X-ray laser output via an online optimizer, which shows improvement in FEL pulse energy. Lastly, as a preparation for electron beam shaping, we use the DMD to measure the photocathode quantum efficiency across cathode surface with an averaged laser rms spot size of 59 μ m . Our experiments demonstrate promising outlook of using DMD to shape ultraviolet lasers for photocathode rf guns with various applications.

Laser Beam Shaping

NASA Astrophysics Data System (ADS)

Aït-Ameur, Kamel; Passilly, Nicolas; de Saint Denis, R.; Fromager, Michaël

2008-09-01

We consider the promising properties of very simple Diffractive Optical Elements (DOE) for reshaping the intensity profile of a laser beam. The first type of DOE that we have considered is a phase aperture which consists in a transparent plate with a circular relief introducing a π phase shift in the central region of the incident beam. The phase aperture is able to convert a Gaussian beam into a super-Gaussian, a ring-shaped or a doughnut profile. The second DOE that has been considered is an adjustable axicon able to transform a Gaussian laser beam into a dark hollow beam or a Bessel-Gauss beam. The desired conical geometry is obtained from a deformable mirror formed by a 2 inches, 0.25mm thick silicon wafer supported by a standard 2 inches optical mount. To achieve the adequate deformation a small metallic ball pushes the back of the mirror wafer. The realized shape is monitored with a Shack-Hartmann wave-front sensor and it is shown that conical shape cannot be achieved. Nevertheless, recorded wave fronts exhibit important third order spherical aberration able to achieve beam profile transformation as conical lenses.

Critical factors for sustainable food procurement in zoological collections.

PubMed

Hanson, Jonathan H

2015-01-01

Food procurement can play an important role in sustainable food supply chain management by zoos, linking organizational operations to the biodiversity conservation and sustainability mission of zoological collections. This study therefore examines the critical factors that shape sustainable food procurement in zoo and aquariums. Using a web-based survey data was collected from 41 members of the British and Irish Association of Zoos and Aquariums (BIAZA). This included information on the sustainable food procurement practices of these institutions for both their human and animal food supply chains, as well as profile information and data on the factors contributing to and inhibiting sustainable procurement practices. Zoological collections operated by charities, and those with a certified sustainability standard, were found to have significantly higher levels of sustainable food procurement. Zoos and aquariums whose human food operations were not contracted to an external party were also found to have significantly higher levels of sustainable food procurement in their human food supply chain. The most important drivers of sustainable food procurement were cost savings, adequate financial support and improved product quality. The highest ranking barriers were higher costs, other issues taking priority and a lack of alternative suppliers. The results suggest that a number of critical factors shape sustainable food procurement in zoological collections in the British Isles. Financial factors, such as cost savings, were important considerations. The significance of mission-related factors, such as charity status, indicated that core values held by zoos and aquariums can also influence their food procurement practices. © 2015 Wiley Periodicals, Inc.

Comparison of Two- and Three-Dimensional Methods for Analysis of Trunk Kinematic Variables in the Golf Swing.

PubMed

Smith, Aimée C; Roberts, Jonathan R; Wallace, Eric S; Kong, Pui; Forrester, Stephanie E

2016-02-01

Two-dimensional methods have been used to compute trunk kinematic variables (flexion/extension, lateral bend, axial rotation) and X-factor (difference in axial rotation between trunk and pelvis) during the golf swing. Recent X-factor studies advocated three-dimensional (3D) analysis due to the errors associated with two-dimensional (2D) methods, but this has not been investigated for all trunk kinematic variables. The purpose of this study was to compare trunk kinematic variables and X-factor calculated by 2D and 3D methods to examine how different approaches influenced their profiles during the swing. Trunk kinematic variables and X-factor were calculated for golfers from vectors projected onto the global laboratory planes and from 3D segment angles. Trunk kinematic variable profiles were similar in shape; however, there were statistically significant differences in trunk flexion (-6.5 ± 3.6°) at top of backswing and trunk right-side lateral bend (8.7 ± 2.9°) at impact. Differences between 2D and 3D X-factor (approximately 16°) could largely be explained by projection errors introduced to the 2D analysis through flexion and lateral bend of the trunk and pelvis segments. The results support the need to use a 3D method for kinematic data calculation to accurately analyze the golf swing.

Longitudinal bunch shaping of picosecond high-charge MeV electron beams

DOE PAGES

Beaudoin, B. L.; Thangaraj, J. C. T.; Edstrom, Jr., D.; ...

2016-10-20

With ever increasing demands for intensities in modern accelerators, the understanding of space-charge effects becomes crucial. Herein are presented measurements of optically shaped picosecond-long electron beams in a superconducting L-band linac over a wide range of charges, from 0.2 nC to 3.4 nC. At low charges, the shape of the electron beam is preserved, while at higher charge densities, modulations on the beam convert to energy modulations. Here, energy profile measurements using a spectrometer and time profile measurements using a streak camera reveal the dynamics of longitudinal space-charge on MeV-scale electron beams.

Factors discriminating among profiles of resilience and psychopathology in children exposed to intimate partner violence (IPV).

PubMed

Graham-Bermann, Sandra A; Gruber, Gabrielle; Howell, Kathryn H; Girz, Laura

2009-09-01

To evaluate the social and emotional adjustment of 219 children in families with varying levels of intimate partner violence (IPV) using a model of risk and protection. To explore factors that differentiate children with poor adjustment from those with resilience. Mothers who experienced IPV in the past year and their children ages 6-12 were interviewed. Standardized measures assessed family violence, parenting, family functioning, maternal mental health, and children's adjustment and beliefs. Using cluster analysis, all cases with valid data on the Child Behavior Checklist, Child Depression Inventory, General Self-Worth and Social Self-Competence measures were described by four profiles of children's adjustment: Severe Adjustment Problems (24%); children who were Struggling (45%); those with Depression Only (11%); and Resilient (20%) with high competence and low adjustment problems. Multinomial logistic regression analyses showed children in the Severe Problems cluster witnessed more family violence and had mothers higher in depression and trauma symptoms than other children. Resilient and Struggling children had mothers with better parenting, more family strengths and no past violent partner. Parents of children with Severe Problems were lacking these attributes. The Depressed profile children witnessed less violence but had greater fears and worries about mother's safety. Factors related to the child, to the mother and to the family distinguish different profiles of adjustment for children exposed to IPV who are living in the community. Resilient children have less violence exposure, fewer fears and worries, and mothers with better mental health and parenting skills, suggesting avenues for intervention with this population. Findings suggest that child adjustment is largely influenced by parent functioning. Thus, services should be targeted at both the child and the parent. Clinical interventions shaped to the unique needs of the child might also be tested with this population.

Imperfect Isolation: Factors and Filters Shaping Madagascar’s Extant Vertebrate Fauna

PubMed Central

Samonds, Karen E.; Godfrey, Laurie R.; Ali, Jason R.; Goodman, Steven M.; Vences, Miguel; Sutherland, Michael R.; Irwin, Mitchell T.; Krause, David W.

2013-01-01

Analyses of phylogenetic topology and estimates of divergence timing have facilitated a reconstruction of Madagascar’s colonization events by vertebrate animals, but that information alone does not reveal the major factors shaping the island’s biogeographic history. Here, we examine profiles of Malagasy vertebrate clades through time within the context of the island’s paleogeographical evolution to determine how particular events influenced the arrival of the island’s extant groups. First we compare vertebrate profiles on Madagascar before and after selected events; then we compare tetrapod profiles on Madagascar to contemporary tetrapod compositions globally. We show that changes from the Mesozoic to the Cenozoic in the proportions of Madagascar’s tetrapod clades (particularly its increase in the representation of birds and mammals) are tied to changes in their relative proportions elsewhere on the globe. Differences in the representation of vertebrate classes from the Mesozoic to the Cenozoic reflect the effects of extinction (i.e., the non-random susceptibility of the different vertebrate clades to purported catastrophic global events 65 million years ago), and new evolutionary opportunities for a subset of vertebrates with the relatively high potential for transoceanic dispersal potential. In comparison, changes in vertebrate class representation during the Cenozoic are minor. Despite the fact that the island’s isolation has resulted in high vertebrate endemism and a unique and taxonomically imbalanced extant vertebrate assemblage (both hailed as testimony to its long isolation), that isolation was never complete. Indeed, Madagascar’s extant tetrapod fauna owes more to colonization during the Cenozoic than to earlier arrivals. Madagascar’s unusual vertebrate assemblage needs to be understood with reference to the basal character of clades originating prior to the K-T extinction, as well as to the differential transoceanic dispersal advantage of other, more recently arriving clades. Thus, the composition of Madagascar’s endemic vertebrate assemblage itself provides evidence of the island's paleogeographic history. PMID:23626770

Imperfect isolation: factors and filters shaping Madagascar's extant vertebrate fauna.

PubMed

Samonds, Karen E; Godfrey, Laurie R; Ali, Jason R; Goodman, Steven M; Vences, Miguel; Sutherland, Michael R; Irwin, Mitchell T; Krause, David W

2013-01-01

Analyses of phylogenetic topology and estimates of divergence timing have facilitated a reconstruction of Madagascar's colonization events by vertebrate animals, but that information alone does not reveal the major factors shaping the island's biogeographic history. Here, we examine profiles of Malagasy vertebrate clades through time within the context of the island's paleogeographical evolution to determine how particular events influenced the arrival of the island's extant groups. First we compare vertebrate profiles on Madagascar before and after selected events; then we compare tetrapod profiles on Madagascar to contemporary tetrapod compositions globally. We show that changes from the Mesozoic to the Cenozoic in the proportions of Madagascar's tetrapod clades (particularly its increase in the representation of birds and mammals) are tied to changes in their relative proportions elsewhere on the globe. Differences in the representation of vertebrate classes from the Mesozoic to the Cenozoic reflect the effects of extinction (i.e., the non-random susceptibility of the different vertebrate clades to purported catastrophic global events 65 million years ago), and new evolutionary opportunities for a subset of vertebrates with the relatively high potential for transoceanic dispersal potential. In comparison, changes in vertebrate class representation during the Cenozoic are minor. Despite the fact that the island's isolation has resulted in high vertebrate endemism and a unique and taxonomically imbalanced extant vertebrate assemblage (both hailed as testimony to its long isolation), that isolation was never complete. Indeed, Madagascar's extant tetrapod fauna owes more to colonization during the Cenozoic than to earlier arrivals. Madagascar's unusual vertebrate assemblage needs to be understood with reference to the basal character of clades originating prior to the K-T extinction, as well as to the differential transoceanic dispersal advantage of other, more recently arriving clades. Thus, the composition of Madagascar's endemic vertebrate assemblage itself provides evidence of the island's paleogeographic history.

Non-axisymmetric equilibrium reconstruction of a current-carrying stellarator using external magnetic and soft x-ray inversion radius measurements

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ma, X., E-mail: xzm0005@auburn.edu; Maurer, D. A.; Knowlton, S. F.

2015-12-15

Non-axisymmetric free-boundary equilibrium reconstructions of stellarator plasmas are performed for discharges in which the magnetic configuration is strongly modified by ohmically driven plasma current. These studies were performed on the compact toroidal hybrid device using the V3FIT reconstruction code with a set of 50 magnetic diagnostics external to the plasma. With the assumption of closed magnetic flux surfaces, the reconstructions using external magnetic measurements allow accurate estimates of the net toroidal flux within the last closed flux surface, the edge safety factor, and the plasma shape of these highly non-axisymmetric plasmas. The inversion radius of standard sawteeth is used tomore » infer the current profile near the magnetic axis; with external magnetic diagnostics alone, the current density profile is imprecisely reconstructed.« less

Non-axisymmetric equilibrium reconstruction of a current-carrying stellarator using external magnetic and soft x-ray inversion radius measurements

NASA Astrophysics Data System (ADS)

Ma, X.; Maurer, D. A.; Knowlton, S. F.; ArchMiller, M. C.; Cianciosa, M. R.; Ennis, D. A.; Hanson, J. D.; Hartwell, G. J.; Hebert, J. D.; Herfindal, J. L.; Pandya, M. D.; Roberds, N. A.; Traverso, P. J.

2015-12-01

Non-axisymmetric free-boundary equilibrium reconstructions of stellarator plasmas are performed for discharges in which the magnetic configuration is strongly modified by ohmically driven plasma current. These studies were performed on the compact toroidal hybrid device using the V3FIT reconstruction code with a set of 50 magnetic diagnostics external to the plasma. With the assumption of closed magnetic flux surfaces, the reconstructions using external magnetic measurements allow accurate estimates of the net toroidal flux within the last closed flux surface, the edge safety factor, and the plasma shape of these highly non-axisymmetric plasmas. The inversion radius of standard sawteeth is used to infer the current profile near the magnetic axis; with external magnetic diagnostics alone, the current density profile is imprecisely reconstructed.

Non-axisymmetric equilibrium reconstruction of a current-carrying stellarator using external magnetic and soft x-ray inversion radius measurements

DOE PAGES

Ma, X.; Maurer, D. A.; Knowlton, Stephen F.; ...

2015-12-22

Non-axisymmetric free-boundary equilibrium reconstructions of stellarator plasmas are performed for discharges in which the magnetic configuration is strongly modified by ohmically driven plasma current. These studies were performed on the compact toroidal hybrid device using the V3FIT reconstruction code with a set of 50 magnetic diagnostics external to the plasma. With the assumption of closed magnetic flux surfaces, the reconstructions using external magnetic measurements allow accurate estimates of the net toroidal flux within the last closed flux surface, the edge safety factor, and the plasma shape of these highly non-axisymmetric plasmas. Lastly, the inversion radius of standard saw-teeth is usedmore » to infer the current profile near the magnetic axis; with external magnetic diagnostics alone, the current density profile is imprecisely reconstructed.« less

SU-F-T-399: Migration of Treatment Planning Systems Without Beam Data Measurement

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tolakanahalli, R; Tewatia, D

2016-06-15

Purpose: Data acquisition for commissioning is steered by Treatment Planning System (TPS) requirements which can be cumbersome and time consuming involving significant clinic downtime. The purpose of this abstract is to answer if we could circumvent this by extracting data from existing TPS and speed up the process. Methods: Commissioning beam data was obtained from a clinically commissioned TPS (Pinnacle™) using Matlab™ generated Pinnacle™ executable scripts to commission a secondary 3D dose verification TPS (Eclipse™). Profiles and output factors for commissioning as required by Eclipse™ were computed on a 50 cm{sup 3} water phantom at a dose grid resolution ofmore » 2mm3. Verification doses were computed and compared to clinical TPS dose profiles as per TG-106 guidelines. Standard patient plans from Pinnacle™ including IMRT and VMAT plans were re-computed keeping the same monitor units (in order to perform true comparison) using Eclipse™. Computed dose was exported back to Pinnacle for comparison to original plans. This methodology enables us to alleviate all ambiguities that arise in such studies. Results: Profile analysis using in-house software for 6x, showed that for all field sizes including small MLC generated fields, 100% of infield and penumbra data points of Eclipse™ match Pinnacle™ generated and measured profiles with 2%/2 mm gamma criteria. Excellent agreement was observed in the penumbra regions, with all data points passing DTA criteria for complex C-shaped and S-shaped profiles. Patient plan dose volume histograms (DVHs) and isodose lines agreed well to within a 1.5% for target coverage. Conclusion: Secondary 3D dose checking is of utmost importance with advanced techniques such as IMRT and VMAT. Migration of TPS is possible without compromising accuracy or enduring the cumbersome measurement of commissioning data. Economizing time for commissioning such a verification system or for migration of TPS can add great QA value and minimize downtime.« less

The integration of Information and Communication Technology into nursing.

PubMed

Lupiáñez-Villanueva, Francisco; Hardey, Michael; Torrent, Joan; Ficapal, Pilar

2011-02-01

To identify and characterise different profiles of nurses' utilization of Information and Communication Technology (ICT) and the Internet and to identify factors that can enhance or inhibit the use of these technologies within nursing. An online survey of the 13,588 members of the Nurses Association of Barcelona who had a registered email account in 2006 was carried out. Factor analysis, cluster analysis and binomial logit model was undertaken. Although most of the nurses (76.70%) are utilizing the Internet within their daily work, multivariate statistics analysis revealed two profiles of the adoption of ICT. The first profile (4.58%) represents those nurses who value ICT and the Internet so that it forms an integral part of their practice. This group is thus referred to as 'integrated nurses'. The second profile (95.42%) represents those nurses who place less emphasis on ICT and the Internet and are consequently labelled 'non-integrated nurses'. From the statistical modelling, it was observed that undertaking research activities an emphasis on international information and a belief that health information available on the Internet was 'very relevant' play a positive and significant role in the probability of being an integrated nurse. The emerging world of the 'integrated nurse' cannot be adequately understood without examining how nurses make use of ICT and the Internet within nursing practice and the way this is shaped by institutional, technical and professional opportunities and constraints. Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.

Method for wafer edge profile extraction using optical images obtained in edge defect inspection process

NASA Astrophysics Data System (ADS)

Okamoto, Hiroaki; Sakaguchi, Naoshi; Hayano, Fuminori

2010-03-01

It is becoming increasingly important to monitor wafer edge profiles in the immersion lithography era. A Nikon edge defect inspection tool acquires the circumferential optical images of the wafer edge during its inspection process. Nikon's unique illumination system and optics make it possible to then convert the brightness data of the captured images to quantifiable edge profile information. During this process the wafer's outer shape is also calculated. Test results show that even newly shipped bare wafers may not have a constant shape over 360 degree. In some cases repeated deformations with 90 degree pitch are observed.

Design and performance of a shape memory alloy-reinforced composite aerodynamic profile

NASA Astrophysics Data System (ADS)

Simpson, J. C.; Boller, C.

2008-04-01

Based on a shape memory alloy (SMA)-reinforced composite developed separately, the applicability of the composite has been demonstrated through realization of a realistically scaled aerodynamic profile of around 0.5 m span by 0.5 m root chord whose skins had been made from this composite. The design, manufacturing and assembly of the profile are described. The curved skins were manufactured with two layers of SMA wires integrated into the layup of aramid fibre prepregs. All SMA wires were connected such that they can be operated as individual sets of wires and at low voltages, similar to the conditions for electrical energy generation in a real aircraft. The profile was then mounted on a vibration test rig and excited by a shaker at its tip which allowed the dynamic performance of the profile to be validated under internal actuation conditions generated through the SMA wires.

Integration of tomato reproductive developmental landmarks and expression profiles, and the effect of SUN on fruit shape

PubMed Central

Xiao, Han; Radovich, Cheryll; Welty, Nicholas; Hsu, Jason; Li, Dongmei; Meulia, Tea; van der Knaap, Esther

2009-01-01

Background Universally accepted landmark stages are necessary to highlight key events in plant reproductive development and to facilitate comparisons among species. Domestication and selection of tomato resulted in many varieties that differ in fruit shape and size. This diversity is useful to unravel underlying molecular and developmental mechanisms that control organ morphology and patterning. The tomato fruit shape gene SUN controls fruit elongation. The most dramatic effect of SUN on fruit shape occurs after pollination and fertilization although a detailed investigation into the timing of the fruit shape change as well as gene expression profiles during critical developmental stages has not been conducted. Results We provide a description of floral and fruit development in a red-fruited closely related wild relative of tomato, Solanum pimpinellifolium accession LA1589. We use established and propose new floral and fruit landmarks to present a framework for tomato developmental studies. In addition, gene expression profiles of three key stages in floral and fruit development are presented, namely floral buds 10 days before anthesis (floral landmark 7), anthesis-stage flowers (floral landmark 10 and fruit landmark 1), and 5 days post anthesis fruit (fruit landmark 3). To demonstrate the utility of the landmarks, we characterize the tomato shape gene SUN in fruit development. SUN controls fruit shape predominantly after fertilization and its effect reaches a maximum at 8 days post-anthesis coinciding with fruit landmark 4 representing the globular embryo stage of seed development. The expression profiles of the NILs that differ at sun show that only 34 genes were differentially expressed and most of them at a less than 2-fold difference. Conclusion The landmarks for flower and fruit development in tomato were outlined and integrated with the effect of SUN on fruit shape. Although we did not identify many genes differentially expressed in the NILs that differ at the sun locus, higher or lower transcript levels for many genes involved in phytohormone biosynthesis or signaling as well as organ identity and patterning of tomato fruit were found between developmental time points. PMID:19422692

Geophysical Features and Inferred Triggering Factors of Submarine Landslides in the Western Continental Margin of the Ulleung Basin, East Sea of Korea

NASA Astrophysics Data System (ADS)

Cukur, D.; Kim, S. P.; Kong, G. S.; Yoon, Y.; Kim, J. K.; Choi, J. G.

2015-12-01

Submarine landslides form very complex features on the seafloor and the associated geological processes are yet to be known completely. Various researches are still undergoing not only for their profound academic significance but also for their hazardous impact potential to seafloor infrastructures and coastal areas. In order to investigate the morphology and cause of landslides along the western margin of the Ulleung Basin in the East Sea, we collected multiple geophysical datasets in the summer of 2015, including sparker, subbottom profiler, and multibeam echosounder. The preliminary analysis of the bathymetric data shows a number of U-shaped scarps that occur on a rather steep slope (up to 10°) in water depths of ~600 m. The scarps cover an area of ~100 km2 and have reliefs of up to 50 m. Seismic data clearly image erosional headwalls and the basal gliding plane which is characterized by a prominent high-amplitude reflector. Chaotic- to transparent-seismic facies, located immediately downslope of the headwall scarps, represent landslide deposits of about 20 m in thickness. At the base of slope, the slides form lens-shaped transparent bodies, resting on well-stratified turbidite deposits. Several V-shaped seafloor depressions near the head of these scarps are seen on the subbottom profiles. These depressions, which are ~5 m deep and ~150 m wide, are interpreted to be representing pockmarks, resulted from upward migration of gas in the sediment layers beneath. The presence of these pockmarks directly above the scars may suggest that the gases and/or gas fluids might be playing an important role for destabilizing slope sediments. Furthermore, subbottom profiles suggest the presence of numerous faults in close vicinity of headwall scarps; some are extending to the seafloor suggesting their recent activity. Earthquakes associated with tectonic activity are indicated to be the cause of these faults. Thus the fault-related earthquakes might be the final triggering mechanism of the landslides along the slopes.

Self-organized pattern on the surface of a metal anode in low-pressure DC discharge

NASA Astrophysics Data System (ADS)

Yaqi, YANG; Weiguo, LI

2018-03-01

Self-organization phenomena on the surface of a metal electrode in low-pressure DC discharge is studied. In this paper, we carry out laboratory investigations of self-organization in a low-pressure test platform for 100-200 mm rod-plane gaps with a needle tip, conical tip and hemispherical tip within 1-10 kPa. The factors influencing the pattern profile are the pressure value, gap length and shape of the electrode, and a variety of pattern structures are observed by changing these factors. With increasing pressure, first the pattern diameter increases and then decreases. With the needle tip, layer structure, single-ring structure and double-ring structure are displayed successively with increasing pressure. With the conical tip, the ring-like structure gradually forms separate spots with increasing pressure. With the hemispherical tip, there are anode spots inside the ring structure. With the increase of gap length, the diameter of the self-organized pattern increases and the profile of the pattern changes. The development process of the pattern contains three key stages: pattern enlargement, pattern stabilization and pattern shrink.

On the line-shape analysis of Compton profiles and its application to neutron scattering

NASA Astrophysics Data System (ADS)

Romanelli, G.; Krzystyniak, M.

2016-05-01

Analytical properties of Compton profiles are used in order to simplify the analysis of neutron Compton scattering experiments. In particular, the possibility to fit the difference of Compton profiles is discussed as a way to greatly decrease the level of complexity of the data treatment, making the analysis easier, faster and more robust. In the context of the novel method proposed, two mathematical models describing the shapes of differenced Compton profiles are discussed: the simple Gaussian approximation for harmonic and isotropic local potential, and an analytical Gauss-Hermite expansion for an anharmonic or anisotropic potential. The method is applied to data collected by VESUVIO spectrometer at ISIS neutron and muon pulsed source (UK) on Copper and Aluminium samples at ambient and low temperatures.

New vistas in refractive laser beam shaping with an analytic design approach

NASA Astrophysics Data System (ADS)

Duerr, Fabian; Thienpont, Hugo

2014-05-01

Many commercial, medical and scientific applications of the laser have been developed since its invention. Some of these applications require a specific beam irradiance distribution to ensure optimal performance. Often, it is possible to apply geometrical methods to design laser beam shapers. This common design approach is based on the ray mapping between the input plane and the output beam. Geometric ray mapping designs with two plano-aspheric lenses have been thoroughly studied in the past. Even though analytic expressions for various ray mapping functions do exist, the surface profiles of the lenses are still calculated numerically. In this work, we present an alternative novel design approach that allows direct calculation of the rotational symmetric lens profiles described by analytic functions. Starting from the example of a basic beam expander, a set of functional differential equations is derived from Fermat's principle. This formalism allows calculating the exact lens profiles described by Taylor series coefficients up to very high orders. To demonstrate the versatility of this new approach, two further cases are solved: a Gaussian to at-top irradiance beam shaping system, and a beam shaping system that generates a more complex dark-hollow Gaussian (donut-like) irradiance profile with zero intensity in the on-axis region. The presented ray tracing results confirm the high accuracy of all calculated solutions and indicate the potential of this design approach for refractive beam shaping applications.

Influence of the shape factor on the flow and heat transfer of a water-based nanofluid in a rotating system

NASA Astrophysics Data System (ADS)

Khan, Umar; Adnan; Ahmed, Naveed; Mohyud-Din, Syed Tauseef

2017-04-01

The flow of a nanofluid between two parallel plates (horizontally placed) has been investigated. Different shapes of nanoparticles (suspended in a base fluid) have been considered and the effect of the shape factor has been analyzed. The lower plate is being stretched in opposite directions with forces of the same magnitude. The plates and nanofluid rotate together with angular velocity Ω. The dimensionless form of the flow model, in the form of a system of ordinary differential equations, is obtained by employing some viable similarity transformations. A well-knows analytical method i.e. Variation of Parameters Method (VPM), has been used to solve the problem. Besides, the same system of equations has also been solved numerically by using the forth order Runge-Kutta method, combined with shooting technique. The graphs highlight the influence of ingrained dimensionless physical parameters on the skin friction coefficient, velocity and temperature profiles, and local rate of heat transfer. It is observed that the velocity increases by varying suction/injection parameter and the temperature seems to drop for higher values of the Reynolds number. A decrement in skin friction is observed for increasing nanoparticles volume fraction. On the other hand, the local rate of heat transfer increases for increasing suction/injection parameter, Reynolds number and nanoparticles volume fraction.

Determination of the effect of source intensity profile on speckle contrast using coherent spatial frequency domain imaging

PubMed Central

Rice, Tyler B.; Konecky, Soren D.; Owen, Christopher; Choi, Bernard; Tromberg, Bruce J.

2012-01-01

Laser Speckle Imaging (LSI) is fast, noninvasive technique to image particle dynamics in scattering media such as biological tissue. While LSI measurements are independent of the overall intensity of the laser source, we find that spatial variations in the laser source profile can impact measured flow rates. This occurs due to differences in average photon path length across the profile, and is of significant concern because all lasers have some degree of natural Gaussian profile in addition to artifacts potentially caused by projecting optics. Two in vivo measurement are performed to show that flow rates differ based on location with respect to the beam profile. A quantitative analysis is then done through a speckle contrast forward model generated within a coherent Spatial Frequency Domain Imaging (cSFDI) formalism. The model predicts remitted speckle contrast as a function of spatial frequency, optical properties, and scattering dynamics. Comparison with experimental speckle contrast images were done using liquid phantoms with known optical properties for three common beam shapes. cSFDI is found to accurately predict speckle contrast for all beam shapes to within 5% root mean square error. Suggestions for improving beam homogeneity are given, including a widening of the natural beam Gaussian, proper diffusing glass spreading, and flat top shaping using microlens arrays. PMID:22741080

A conceptual model for the development of pristine drainage systems during exhumation of metamorphic core complexes

NASA Astrophysics Data System (ADS)

Trost, Georg; Neubauer, Franz; Robl, Jörg

2017-04-01

Metamorphic core complexes (MCCs) are defined as large scale geological features of domal shape. The essential characteristic comprises metamorphic rocks, which have been exhumed from lower crustal levels and now are exposed to the surface. The updoming process occurs at different tectonic settings of high strain zones initially exposing pristine gently dipping fault planes to Earth's surface. Consequently, the dome shape highly influences the type of adaption of the drainage systems to the active landforms. However, drainage systems and their characteristic metrics in regions shaped by MCCs have only been sparsely investigated and were not examined regarding the distinction between different MCC-types (A-type, B-type, C-type). In this study we investigate the drainage patterns of MCCs formed by different tectonic settings and build up a conceptual model for the development of the drainage systems under these conditions. We apply the χ-method to detect variations in uplift, as well as spatial unconformities in the drainage patterns. The χ-method is a mathematical approach to transform stream longitudinal profiles to the χ space where the slope of steady state profiles is solely dependent on uplift rate and bedrock erodibility. From this transformation we calculate color-coded χ-maps and χ-profiles of the main streams draining the MCCs. The applied method allows the interpretation of channel metrics in terms of (a) spatial gradients in uplift rate and (b) the time dependent evolution of drainage divides including drainage divide migration. Our results show a high variation in the shape and greatest elevation of the χ-profiles. This indicates the migration of active uplift zones along the dome axes. Even though only MCCs younger than Miocene age are investigated, the shape of the χ-profiles clearly points to different development stages of these areas. K-profiles plotted over the detachment underlying an active updoming process show concave shaped χ-profiles. In contrast, χ-profiles plotted over the detachments coined by long-term erosional processes tend to preserve prominent knickpoints in linearly proceeding profiles. Additionally, the migration of the watersheds indicates lateral extension of the domes, potentially influenced by rolling hinges. MCCs subjected to active uplift show proceeding stream piracy of streams following tectonically induced lineaments. Drainage systems have systematically deflected streams at the edges of the dome structures. The deflections can be especially observed at A-type domes (dome axis oriented parallel to the direction of extension). We conclude that our observations can be explained by the Rolling-Hinge model for MCC-formation. This model is applicable for all types of MCCs and gives the mechanical basis for the updoming process and such for the first stages of drainage development. Some of the observed features are dedicated to ongoing erosional processes and hence represent later phases of MCC development.

Estimating local noise power spectrum from a few FBP-reconstructed CT scans

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zeng, Rongping, E-mail: rongping.zeng@fda.hhs.gov; Gavrielides, Marios A.; Petrick, Nicholas

Purpose: Traditional ways to estimate 2D CT noise power spectrum (NPS) involve an ensemble average of the power spectrums of many noisy scans. When only a few scans are available, regions of interest are often extracted from different locations to obtain sufficient samples to estimate the NPS. Using image samples from different locations ignores the nonstationarity of CT noise and thus cannot accurately characterize its local properties. The purpose of this work is to develop a method to estimate local NPS using only a few fan-beam CT scans. Methods: As a result of FBP reconstruction, the CT NPS has themore » same radial profile shape for all projection angles, with the magnitude varying with the noise level in the raw data measurement. This allows a 2D CT NPS to be factored into products of a 1D angular and a 1D radial function in polar coordinates. The polar separability of CT NPS greatly reduces the data requirement for estimating the NPS. The authors use this property and derive a radial NPS estimation method: in brief, the radial profile shape is estimated from a traditional NPS based on image samples extracted at multiple locations. The amplitudes are estimated by fitting the traditional local NPS to the estimated radial profile shape. The estimated radial profile shape and amplitudes are then combined to form a final estimate of the local NPS. We evaluate the accuracy of the radial NPS method and compared it to traditional NPS methods in terms of normalized mean squared error (NMSE) and signal detectability index. Results: For both simulated and real CT data sets, the local NPS estimated with no more than six scans using the radial NPS method was very close to the reference NPS, according to the metrics of NMSE and detectability index. Even with only two scans, the radial NPS method was able to achieve a fairly good accuracy. Compared to those estimated using traditional NPS methods, the accuracy improvement was substantial when a few scans were available. Conclusions: The radial NPS method was shown to be accurate and efficient in estimating the local NPS of FBP-reconstructed 2D CT images. It presents strong advantages over traditional NPS methods when the number of scans is limited and can be extended to estimate the in-plane NPS of cone-beam CT and multislice helical CT scans.« less

Deriving amplification factors from simple site parameters using generalized regression neural networks: implications for relevant site proxies

NASA Astrophysics Data System (ADS)

Boudghene Stambouli, Ahmed; Zendagui, Djawad; Bard, Pierre-Yves; Derras, Boumédiène

2017-07-01

Most modern seismic codes account for site effects using an amplification factor (AF) that modifies the rock acceleration response spectra in relation to a "site condition proxy," i.e., a parameter related to the velocity profile at the site under consideration. Therefore, for practical purposes, it is interesting to identify the site parameters that best control the frequency-dependent shape of the AF. The goal of the present study is to provide a quantitative assessment of the performance of various site condition proxies to predict the main AF features, including the often used short- and mid-period amplification factors, Fa and Fv, proposed by Borcherdt (in Earthq Spectra 10:617-653, 1994). In this context, the linear, viscoelastic responses of a set of 858 actual soil columns from Japan, the USA, and Europe are computed for a set of 14 real accelerograms with varying frequency contents. The correlation between the corresponding site-specific average amplification factors and several site proxies (considered alone or as multiple combinations) is analyzed using the generalized regression neural network (GRNN). The performance of each site proxy combination is assessed through the variance reduction with respect to the initial amplification factor variability of the 858 profiles. Both the whole period range and specific short- and mid-period ranges associated with the Borcherdt factors Fa and Fv are considered. The actual amplification factor of an arbitrary soil profile is found to be satisfactorily approximated with a limited number of site proxies (4-6). As the usual code practice implies a lower number of site proxies (generally one, sometimes two), a sensitivity analysis is conducted to identify the "best performing" site parameters. The best one is the overall velocity contrast between underlying bedrock and minimum velocity in the soil column. Because these are the most difficult and expensive parameters to measure, especially for thick deposits, other more convenient parameters are preferred, especially the couple ( {V_{{{s}30}} ,f0 } ) that leads to a variance reduction in at least 60%. From a code perspective, equations and plots are provided describing the dependence of the short- and mid-period amplification factors Fa and Fv on these two parameters. The robustness of the results is analyzed by performing a similar analysis for two alternative sets of velocity profiles, for which the bedrock velocity is constrained to have the same value for all velocity profiles, which is not the case in the original set.[Figure not available: see fulltext.

Einasto profiles and the dark matter power spectrum

NASA Astrophysics Data System (ADS)

Ludlow, Aaron D.; Angulo, Raúl E.

2017-02-01

We study the mass accretion histories (MAHs) and density profiles of dark matter haloes using N-body simulations of self-similar gravitational clustering from scale-free power spectra, P(k) ∝ kn. We pay particular attention to the density profile curvature, which we characterize using the shape parameter, α, of an Einasto profile. In agreement with previous findings, our results suggest that, despite vast differences in their MAHs, the density profiles of virialized haloes are remarkably alike. Nonetheless, clear departures from self-similarity are evident: For a given spectral index, α increases slightly but systematically with `peak height', ν ≡ δsc/σ(M, z), regardless of mass or redshift. More importantly, however, the `α-ν' relation depends on n: The steeper the initial power spectrum, the more gradual the curvature of both the mean MAHs and mean density profiles. These results are consistent with previous findings connecting the shapes of halo mass profiles and MAHs, and imply that dark matter haloes are not structurally self-similar but, through the merger history, retain a memory of the linear density field from which they form.

SU-F-T-428: An Optimization-Based Commissioning Tool for Finite Size Pencil Beam Dose Calculations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Li, Y; Tian, Z; Song, T

Purpose: Finite size pencil beam (FSPB) algorithms are commonly used to pre-calculate the beamlet dose distribution for IMRT treatment planning. FSPB commissioning, which usually requires fine tuning of the FSPB kernel parameters, is crucial to the dose calculation accuracy and hence the plan quality. Yet due to the large number of beamlets, FSPB commissioning could be very tedious. This abstract reports an optimization-based FSPB commissioning tool we have developed in MatLab to facilitate the commissioning. Methods: A FSPB dose kernel generally contains two types of parameters: the profile parameters determining the dose kernel shape, and a 2D scaling factors accountingmore » for the longitudinal and off-axis corrections. The former were fitted using the penumbra of a reference broad beam’s dose profile with Levenberg-Marquardt algorithm. Since the dose distribution of a broad beam is simply a linear superposition of the dose kernel of each beamlet calculated with the fitted profile parameters and scaled using the scaling factors, these factors could be determined by solving an optimization problem which minimizes the discrepancies between the calculated dose of broad beams and the reference dose. Results: We have commissioned a FSPB algorithm for three linac photon beams (6MV, 15MV and 6MVFFF). Dose of four field sizes (6*6cm2, 10*10cm2, 15*15cm2 and 20*20cm2) were calculated and compared with the reference dose exported from Eclipse TPS system. For depth dose curves, the differences are less than 1% of maximum dose after maximum dose depth for most cases. For lateral dose profiles, the differences are less than 2% of central dose at inner-beam regions. The differences of the output factors are within 1% for all the three beams. Conclusion: We have developed an optimization-based commissioning tool for FSPB algorithms to facilitate the commissioning, providing sufficient accuracy of beamlet dose calculation for IMRT optimization.« less

Child cortisol moderates the association between family routines and emotion regulation in low-income children

PubMed Central

Miller, Alison L.; Song, Ju-Hyun; Sturza, Julie; Lumeng, Julie C.; Rosenblum, Katherine; Kaciroti, Niko; Vazquez, Delia M.

2018-01-01

Biological and social influences both shape emotion regulation. In 380 low-income children, we tested whether biological stress profile (cortisol) moderated the association among positive and negative home environment factors (routines; chaos) and emotion regulation (negative lability; positive regulation). Children (M age = 50.6, SD = 6.4 months) provided saliva samples to assess diurnal cortisol parameters across 3 days. Parents reported on home environment and child emotion regulation. Structural equation modeling was used to test whether cortisol parameters moderated associations between home environment and child emotion regulation. Results showed that home chaos was negatively associated with emotion regulation outcomes; cortisol did not moderate the association. Child cortisol level moderated the routines-emotion regulation association such that lack of routine was most strongly associated with poor emotion regulation among children with lower cortisol output. Findings suggest that underlying child stress biology may shape response to environmental influences. PMID:27594200

Advanced photonic filters based on cascaded Sagnac loop reflector resonators in silicon-on-insulator nanowires

NASA Astrophysics Data System (ADS)

Wu, Jiayang; Moein, Tania; Xu, Xingyuan; Moss, David J.

2018-04-01

We demonstrate advanced integrated photonic filters in silicon-on-insulator (SOI) nanowires implemented by cascaded Sagnac loop reflector (CSLR) resonators. We investigate mode splitting in these standing-wave (SW) resonators and demonstrate its use for engineering the spectral profile of on-chip photonic filters. By changing the reflectivity of the Sagnac loop reflectors (SLRs) and the phase shifts along the connecting waveguides, we tailor mode splitting in the CSLR resonators to achieve a wide range of filter shapes for diverse applications including enhanced light trapping, flat-top filtering, Q factor enhancement, and signal reshaping. We present the theoretical designs and compare the CSLR resonators with three, four, and eight SLRs fabricated in SOI. We achieve versatile filter shapes in the measured transmission spectra via diverse mode splitting that agree well with theory. This work confirms the effectiveness of using CSLR resonators as integrated multi-functional SW filters for flexible spectral engineering.

Design of relative motion and attitude profiles for three-dimensional resident space object imaging with a laser rangefinder

NASA Astrophysics Data System (ADS)

Nayak, M.; Beck, J.; Udrea, B.

This paper focuses on the aerospace application of a single beam laser rangefinder (LRF) for 3D imaging, shape detection, and reconstruction in the context of a space-based space situational awareness (SSA) mission scenario. The primary limitation to 3D imaging from LRF point clouds is the one-dimensional nature of the single beam measurements. A method that combines relative orbital motion and scanning attitude motion to generate point clouds has been developed and the design and characterization of multiple relative motion and attitude maneuver profiles are presented. The target resident space object (RSO) has the shape of a generic telecommunications satellite. The shape and attitude of the RSO are unknown to the chaser satellite however, it is assumed that the RSO is un-cooperative and has fixed inertial pointing. All sensors in the metrology chain are assumed ideal. A previous study by the authors used pure Keplerian motion to perform a similar 3D imaging mission at an asteroid. A new baseline for proximity operations maneuvers for LRF scanning, based on a waypoint adaptation of the Hill-Clohessy-Wiltshire (HCW) equations is examined. Propellant expenditure for each waypoint profile is discussed and combinations of relative motion and attitude maneuvers that minimize the propellant used to achieve a minimum required point cloud density are studied. Both LRF strike-point coverage and point cloud density are maximized; the capability for 3D shape registration and reconstruction from point clouds generated with a single beam LRF without catalog comparison is proven. Next, a method of using edge detection algorithms to process a point cloud into a 3D modeled image containing reconstructed shapes is presented. Weighted accuracy of edge reconstruction with respect to the true model is used to calculate a qualitative “ metric” that evaluates effectiveness of coverage. Both edge recognition algorithms and the metric are independent of point cloud densit- , therefore they are utilized to compare the quality of point clouds generated by various attitude and waypoint command profiles. The RSO model incorporates diverse irregular protruding shapes, such as open sensor covers, instrument pods and solar arrays, to test the limits of the algorithms. This analysis is used to mathematically prove that point clouds generated by a single-beam LRF can achieve sufficient edge recognition accuracy for SSA applications, with meaningful shape information extractable even from sparse point clouds. For all command profiles, reconstruction of RSO shapes from the point clouds generated with the proposed method are compared to the truth model and conclusions are drawn regarding their fidelity.

Ripening and storage conditions of Chétoui and Arbequina olives: Part II. Effect on olive endogenous enzymes and virgin olive oil secoiridoid profile determined by high resolution mass spectrometry.

PubMed

Hachicha Hbaieb, Rim; Kotti, Faten; Cortes-Francisco, Nuria; Caixach, Josep; Gargouri, Mohamed; Vichi, Stefania

2016-11-01

Several factors affect virgin olive oil (VOO) phenolic profile. The aim of this study was to monitor olive hydrolytic (β-glucosidase) and oxidative (peroxydase, POX, and polyphenoloxydase, PPO) enzymes during olive ripening and storage and to determine their capacity to shape VOO phenolic profile. To this end, olives from the cultivars Chétoui and Arbequina were stored at 4°C or 25°C for 4weeks and their enzymatic activities and oil phenolic profiles were compared to those of ripening olives. We observed different trends in enzymes activities according to cultivar and storage temperature. Secoiridoid compounds, determined by high resolution mass spectrometry (HRMS), and their deacetoxylated, oxygenated, and deacetoxy-oxygenated derivatives were identified and their contents differed between the cultivars according to olive ripening degree and storage conditions. These differences could be due to β-glucosidase, POX and PPO activities changes during olive ripening and storage. Results also show that oxidised phenolic compounds could be a marker of VOO ''freshness". Copyright © 2016 Elsevier Ltd. All rights reserved.

Determination of current and rotational transform profiles in a current-carrying stellarator using soft x-ray emissivity measurements

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ma, X.; Cianciosa, M. R.; Ennis, D. A.

In this research, collimated soft X-ray (SXR) emissivity measurements from multi-channel cameras on the Compact Toroidal Hybrid (CTH) tokamak/torsatron device are incorporated in the 3D equilibrium reconstruction code V3FIT to reconstruct the shape of flux surfaces and infer the current distribution within the plasma. Equilibrium reconstructions of sawtoothing plasmas that use data from both SXR and external magnetic diagnostics show the central safety factor to be near unity under the assumption that SXR iso-emissivity contours lie on magnetic flux surfaces. The reconstruction results are consistent with those using the external magnetic data and a constraint on the location of qmore » = 1 surfaces determined from the sawtooth inversion surface extracted from SXR brightness profiles. The agreement justifies the use of approximating SXR emission as a flux function in CTH, at least within the core of the plasma, subject to the spatial resolution of the SXR diagnostics. Lastly, this improved reconstruction of the central current density indicates that the current profile peakedness decreases with increasing external transform and that the internal inductance is not a relevant measure of how peaked the current profile is in hybrid discharges.« less

Determination of current and rotational transform profiles in a current-carrying stellarator using soft x-ray emissivity measurements

NASA Astrophysics Data System (ADS)

Ma, X.; Cianciosa, M. R.; Ennis, D. A.; Hanson, J. D.; Hartwell, G. J.; Herfindal, J. L.; Howell, E. C.; Knowlton, S. F.; Maurer, D. A.; Traverso, P. J.

2018-01-01

Collimated soft X-ray (SXR) emissivity measurements from multi-channel cameras on the Compact Toroidal Hybrid (CTH) tokamak/torsatron device are incorporated in the 3D equilibrium reconstruction code V3FIT to reconstruct the shape of flux surfaces and infer the current distribution within the plasma. Equilibrium reconstructions of sawtoothing plasmas that use data from both SXR and external magnetic diagnostics show the central safety factor to be near unity under the assumption that SXR iso-emissivity contours lie on magnetic flux surfaces. The reconstruction results are consistent with those using the external magnetic data and a constraint on the location of q = 1 surfaces determined from the sawtooth inversion surface extracted from SXR brightness profiles. The agreement justifies the use of approximating SXR emission as a flux function in CTH, at least within the core of the plasma, subject to the spatial resolution of the SXR diagnostics. This improved reconstruction of the central current density indicates that the current profile peakedness decreases with increasing external transform and that the internal inductance is not a relevant measure of how peaked the current profile is in hybrid discharges.

Determination of current and rotational transform profiles in a current-carrying stellarator using soft x-ray emissivity measurements

DOE PAGES

Ma, X.; Cianciosa, M. R.; Ennis, D. A.; ...

2018-01-31

In this research, collimated soft X-ray (SXR) emissivity measurements from multi-channel cameras on the Compact Toroidal Hybrid (CTH) tokamak/torsatron device are incorporated in the 3D equilibrium reconstruction code V3FIT to reconstruct the shape of flux surfaces and infer the current distribution within the plasma. Equilibrium reconstructions of sawtoothing plasmas that use data from both SXR and external magnetic diagnostics show the central safety factor to be near unity under the assumption that SXR iso-emissivity contours lie on magnetic flux surfaces. The reconstruction results are consistent with those using the external magnetic data and a constraint on the location of qmore » = 1 surfaces determined from the sawtooth inversion surface extracted from SXR brightness profiles. The agreement justifies the use of approximating SXR emission as a flux function in CTH, at least within the core of the plasma, subject to the spatial resolution of the SXR diagnostics. Lastly, this improved reconstruction of the central current density indicates that the current profile peakedness decreases with increasing external transform and that the internal inductance is not a relevant measure of how peaked the current profile is in hybrid discharges.« less

EDGES result versus CMB and low-redshift constraints on ionization histories

NASA Astrophysics Data System (ADS)

Witte, Samuel; Villanueva-Domingo, Pablo; Gariazzo, Stefano; Mena, Olga; Palomares-Ruiz, Sergio

2018-05-01

We examine the results from the Experiment to Detect the Global Epoch of Reionization Signature (EDGES), which has recently claimed the detection of a strong absorption in the 21 cm hyperfine transition line of neutral hydrogen, at redshifts demarcating the early stages of star formation. More concretely, we study the compatibility of the shape of the EDGES absorption profile, centered at a redshift of z ˜17.2 , with measurements of the reionization optical depth, the Gunn-Peterson optical depth, and Lyman-α emission from star-forming galaxies, for a variety of possible reionization models within the standard Λ CDM framework (that is, a Universe with a cosmological constant Λ and cold dark matter CDM). When, conservatively, we only try to accommodate the location of the absorption dip, we identify a region in the parameter space of the astrophysical parameters that successfully explains all of the aforementioned observations. However, one of the most abnormal features of the EDGES measurement is the absorption amplitude, which is roughly a factor of 2 larger than the maximum allowed value in the Λ CDM framework. We point out that the simple considered astrophysical models that produce the largest absorption amplitudes are unable to explain the depth of the dip and of reproducing the observed shape of the absorption profile.

Experimental evaluation of x-ray acoustic computed tomography for radiotherapy dosimetry applications.

PubMed

Hickling, Susannah; Lei, Hao; Hobson, Maritza; Léger, Pierre; Wang, Xueding; El Naqa, Issam

2017-02-01

The aim of this work was to experimentally demonstrate the feasibility of x-ray acoustic computed tomography (XACT) as a dosimetry tool in a clinical radiotherapy environment. The acoustic waves induced following a single pulse of linear accelerator irradiation in a water tank were detected with an immersion ultrasound transducer. By rotating the collimator and keeping the transducer stationary, acoustic signals at varying angles surrounding the field were detected and reconstructed to form an XACT image. Simulated XACT images were obtained using a previously developed simulation workflow. Profiles extracted from experimental and simulated XACT images were compared to profiles measured with an ion chamber. A variety of radiation field sizes and shapes were investigated. XACT images resembling the geometry of the delivered radiation field were obtained for fields ranging from simple squares to more complex shapes. When comparing profiles extracted from simulated and experimental XACT images of a 4 cm × 4 cm field, 97% of points were found to pass a 3%/3 mm gamma test. Agreement between simulated and experimental XACT images worsened when comparing fields with fine details. Profiles extracted from experimental XACT images were compared to profiles obtained through clinical ion chamber measurements, confirming that the intensity of XACT images is related to deposited radiation dose. Seventy-seven percent of the points in a profile extracted from an experimental XACT image of a 4 cm × 4 cm field passed a 7%/4 mm gamma test when compared to an ion chamber measured profile. In a complicated puzzle-piece shaped field, 86% of the points in an XACT extracted profile passed a 7%/4 mm gamma test. XACT images with intensity related to the spatial distribution of deposited dose in a water tank were formed for a variety of field sizes and shapes. XACT has the potential to be a useful tool for absolute, relative and in vivo dosimetry. © 2016 American Association of Physicists in Medicine.

Forming three-dimensional closed shapes from two-dimensional soft ribbons by controlled buckling

PubMed Central

Aoki, Michio

2018-01-01

Conventional manufacturing techniques—moulding, machining and casting—exist to produce three-dimensional (3D) shapes. However, these industrial processes are typically geared for mass production and are not directly applicable to residential settings, where inexpensive and versatile tools are desirable. Moreover, those techniques are, in general, not adequate to process soft elastic materials. Here, we introduce a new concept of forming 3D closed hollow shapes from two-dimensional (2D) elastic ribbons by controlled buckling. We numerically and experimentally characterize how the profile and thickness of the ribbon determine its buckled shape. We find a 2D master profile with which various elliptical 3D shapes can be formed. More complex natural and artificial hollow shapes, such as strawberry, hourglass and wheel, can also be achieved via strategic design and pattern engraving on the ribbons. The nonlinear response of the post-buckling regime is rationalized through finite-element analysis, which shows good quantitative agreement with experiments. This robust fabrication should complement conventional techniques and provide a rich arena for future studies on the mechanics and new applications of elastic hollow structures. PMID:29515894

Forming three-dimensional closed shapes from two-dimensional soft ribbons by controlled buckling

NASA Astrophysics Data System (ADS)

Aoki, Michio; Juang, Jia-Yang

2018-02-01

Conventional manufacturing techniques-moulding, machining and casting-exist to produce three-dimensional (3D) shapes. However, these industrial processes are typically geared for mass production and are not directly applicable to residential settings, where inexpensive and versatile tools are desirable. Moreover, those techniques are, in general, not adequate to process soft elastic materials. Here, we introduce a new concept of forming 3D closed hollow shapes from two-dimensional (2D) elastic ribbons by controlled buckling. We numerically and experimentally characterize how the profile and thickness of the ribbon determine its buckled shape. We find a 2D master profile with which various elliptical 3D shapes can be formed. More complex natural and artificial hollow shapes, such as strawberry, hourglass and wheel, can also be achieved via strategic design and pattern engraving on the ribbons. The nonlinear response of the post-buckling regime is rationalized through finite-element analysis, which shows good quantitative agreement with experiments. This robust fabrication should complement conventional techniques and provide a rich arena for future studies on the mechanics and new applications of elastic hollow structures.

Total magnitudes of Virgo galaxies - III. Scale errors in the Reference Catalogue of Bright Galaxies T system and light-profile distortion by resolution-degrading and differential-distance effects

NASA Astrophysics Data System (ADS)

Young, Christopher Ke-shih

2004-11-01

We investigate the BT magnitude scales of the Second and Third Reference Catalogues of Bright Galaxies, finding both scales to be reasonably reliable for 11.5 <~Bt<~ 14.0. However, large-scale errors of 0.26 and 0.24mag per unit mag interval respectively are uncovered for early-type galaxies at the bright ends, whilst even larger ones of 0.74 and 0.36mag per unit mag interval are found for galaxies of all morphological types at the faint ends. We attribute this situation to several effects already discussed by Young et al. and Young (Paper I), including the application of relatively inflexible growth-curve models that are only in a few specific cases appropriate to the galaxies concerned. Of particular interest to this study though, we find that the apparent profile shapes of giant galaxies in the Virgo direction of cz < 15000 km s-1 tend to be less centrally concentrated the greater their distance. This demonstrates that even for relatively nearby galaxies, the distortion of the overall shapes of light profiles by resolution-degrading effects such as seeing and data smoothing, as originally predicted and modelled by Young & Currie and Young et al., is a significant effect. It is, therefore, not good practice simply to extrapolate the profiles of galaxies of identical intrinsic size and intrinsic profile shape (i.e. identical morphology) by means of the same growth-curve model, unless the galaxies are known a priori to be at the same distance and unless their photometry is of the same angular resolution. We also investigate the total-magnitude scale of the catalogue of photometric types of Prugniel & Héraudeau, finding it to be much more reliable than the BT one. However, we argue that photometric type is really a measure of apparent profile shape (i.e. intrinsic profile shape after scale reduction on account of distance followed by convolution with a seeing disc and often a smoothing function as well). Strictly, it should therefore only be applicable to comparisons between galaxies that are already known to be at similar distances provided that their photometry is also of similar angular resolution. Clearly, this must complicate attempts to construct quantitative morphological classification schemes for galaxies.

Minimum magnetic curvature for resilient divertors using Compact Toroidal Hybrid geometry

NASA Astrophysics Data System (ADS)

Bader, A.; Hegna, C. C.; Cianciosa, M.; Hartwell, G. J.

2018-05-01

The properties of resilient divertors are explored using equilibria derived from Compact Toroidal Hybrid (CTH) geometries. Resilience is defined here as the robustness of the strike point patterns as the plasma geometry and/or plasma profiles are changed. The addition of plasma current in the CTH configurations significantly alters the shape of the last closed flux surface and the rotational transform profile, however, it does not alter the strike point pattern on the target plates, and hence has resilient divertor features. The limits of when a configuration transforms to a resilient configuration is then explored. New CTH-like configurations are generated that vary from a perfectly circular cross section to configurations with increasing amounts of toroidal shaping. It is found that even small amounts of toroidal shaping lead to strike point localization that is similar to the standard CTH configuration. These results show that only a small degree of three-dimensional shaping is necessary to produce a resilient divertor, implying that any highly shaped optimized stellarator will possess the resilient divertor property.

Pulse generation and preamplification for long pulse beamlines of Orion laser facility.

PubMed

Hillier, David I; Winter, David N; Hopps, Nicholas W

2010-06-01

We describe the pulse generation, shaping, and preamplification system for the nanosecond beamlines of the Orion laser facility. The system generates shaped laser pulses of up to approximately 1 J of 100 ps-5 ns duration with a programmable temporal profile. The laser has a 30th-power supergaussian spatial profile and is diffraction limited. The system is capable of imposing 2D smoothing by spectral dispersion upon the beam, which will produce a nonuniformity of 10% rms at the target.

Numerical investigation of galloping instabilities in Z-shaped profiles.

PubMed

Gomez, Ignacio; Chavez, Miguel; Alonso, Gustavo; Valero, Eusebio

2014-01-01

Aeroelastic effects are relatively common in the design of modern civil constructions such as office blocks, airport terminal buildings, and factories. Typical flexible structures exposed to the action of wind are shading devices, normally slats or louvers. A typical cross-section for such elements is a Z-shaped profile, made out of a central web and two-side wings. Galloping instabilities are often determined in practice using the Glauert-Den Hartog criterion. This criterion relies on accurate predictions of the dependence of the aerodynamic force coefficients with the angle of attack. The results of a parametric analysis based on a numerical analysis and performed on different Z-shaped louvers to determine translational galloping instability regions are presented in this paper. These numerical analysis results have been validated with a parametric analysis of Z-shaped profiles based on static wind tunnel tests. In order to perform this validation, the DLR TAU Code, which is a standard code within the European aeronautical industry, has been used. This study highlights the focus on the numerical prediction of the effect of galloping, which is shown in a visible way, through stability maps. Comparisons between numerical and experimental data are presented with respect to various meshes and turbulence models.

Role of LA Shape in Predicting Embolic Cerebrovascular Events in Mitral Stenosis

PubMed Central

Nunes, Maria Carmo P.; Handschumacher, Mark D.; Levine, Robert A.; Barbosa, Marcia M.; Carvalho, Vinicius T.; Esteves, William A.; Zeng, Xin; Guerrero, J. Luis; Zheng, Hui; Tan, Timothy C.; Hung, Judy

2015-01-01

OBJECTIVES This study was designed to assess the role of left atrial (LA) shape in predicting embolic cerebrovascular events (ECE) in patients with mitral stenosis (MS). BACKGROUND Patients with rheumatic MS are at increased risk for ECE. LA remodeling in response to MS involves not only chamber dilation but also changes in the shape. We hypothesized that a more spherical LA shape may be associated with increased embolic events due to predisposition to thrombus formation or to atrial arrhythmias compared with an elliptical-shaped LA of comparable volume. METHODS A total of 212 patients with MS and 20 control subjects were enrolled. LA volume, LA emptying fraction, and cross-sectional area were measured by 3-dimensional (3D) transthoracic echocardiography. LA shape was expressed as the ratio of measured LA end-systolic volume to hypothetical sphere volume ([4/3π r3] where r was obtained from 3D cross-sectional area). The lower the LA shape index, the more spherical the shape. RESULTS A total of 41 patients presented with ECE at the time of enrollment or during follow-up. On multivariate analysis, LA 3D emptying fraction (adjusted odds ratio [OR]: 0.96; 95% confidence interval [CI]: 0.92 to 0.99; p = 0.028) and LA shape index (OR: 0.73; 95% CI: 0.61 to 0.87; p < 0.001) emerged as important factors associated with ECE, after adjustment for age and anticoagulation therapy. In patients in sinus rhythm, LA shape index remained associated with ECE (OR: 0.79; 95% CI: 0.67 to 0.94; p = 0.007), independent of age and LA function. An in vitro phantom atrial model demonstrated more stagnant flow profiles in spherical compared with ellipsoidal chamber. CONCLUSIONS In rheumatic MS patients, differential LA remodeling affects ECE risk. A more spherical LA shape was independently associated with an increased risk for ECE, adding incremental value in predicting events beyond that provided by age and LA function. PMID:24831206

The implementation of non-Voigt line profiles in the HITRAN database: H2 case study

NASA Astrophysics Data System (ADS)

Wcisło, P.; Gordon, I. E.; Tran, H.; Tan, Y.; Hu, S.-M.; Campargue, A.; Kassi, S.; Romanini, D.; Hill, C.; Kochanov, R. V.; Rothman, L. S.

2016-07-01

Experimental capabilities of molecular spectroscopy and its applications nowadays require a sub-percent or even sub-per mille accuracy of the representation of the shapes of molecular transitions. This implies the necessity of using more advanced line-shape models which are characterized by many more parameters than a simple Voigt profile. It is a great challenge for modern molecular spectral databases to store and maintain the extended set of line-shape parameters as well as their temperature dependences. It is even more challenging to reliably retrieve these parameters from experimental spectra over a large range of pressures and temperatures. In this paper we address this problem starting from the case of the H2 molecule for which the non-Voigt line-shape effects are exceptionally pronounced. For this purpose we reanalyzed the experimental data reported in the literature. In particular, we performed detailed line-shape analysis of high-quality spectra obtained with cavity-enhanced techniques. We also report the first high-quality cavity-enhanced measurement of the H2 fundamental vibrational mode. We develop a correction to the Hartmann-Tran profile (HTP) which adjusts the HTP to the particular model of the velocity-changing collisions. This allows the measured spectra to be better represented over a wide range of pressures. The problem of storing the HTP parameters in the HITRAN database together with their temperature dependences is also discussed.

Laser beam-profile impression and target thickness impact on laser-accelerated protons

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schollmeier, M.; Harres, K.; Nuernberg, F.

Experimental results on the influence of the laser focal spot shape onto the beam profile of laser-accelerated protons from gold foils are reported. The targets' microgrooved rear side, together with a stack of radiochromic films, allowed us to deduce the energy-dependent proton source-shape and size, respectively. The experiments show, that shape and size of the proton source depend only weakly on target thickness as well as shape of the laser focus, although they strongly influence the proton's intensity distribution. It was shown that the laser creates an electron beam that closely follows the laser beam topology, which is maintained duringmore » the propagation through the target. Protons are then accelerated from the rear side with an electron created electric field of a similar shape. Simulations with the Sheath-Accelerated Beam Ray-tracing for IoN Analysis code SABRINA, which calculates the proton distribution in the detector for a given laser-beam profile, show that the electron distribution during the transport through a thick target (50 {mu}m Au) is only modified due to multiple small angle scattering. Thin targets (10 {mu}m) show large source sizes of over 100 {mu}m diameter for 5 MeV protons, which cannot be explained by multiple scattering only and are most likely the result of refluxing electrons.« less

FunChIP: an R/Bioconductor package for functional classification of ChIP-seq shapes.

PubMed

Parodi, Alice C L; Sangalli, Laura M; Vantini, Simone; Amati, Bruno; Secchi, Piercesare; Morelli, Marco J

2017-08-15

Chromatin Immunoprecipitation followed by sequencing (ChIP-seq) generates local accumulations of sequencing reads on the genome ("peaks"), which correspond to specific protein-DNA interactions or chromatin modifications. Peaks are detected by considering their total area above a background signal, usually neglecting their shapes, which instead may convey additional biological information. We present FunChIP, an R/Bioconductor package for clustering peaks according to a functional representation of their shapes: after approximating their profiles with cubic B-splines, FunChIP minimizes their functional distance and classifies the peaks applying a k-mean alignment and clustering algorithm. The whole pipeline is user-friendly and provides visualization functions for a quick inspection of the results. An application to the transcription factor Myc in 3T9 murine fibroblasts shows that clusters of peaks with different shapes are associated with different genomic locations and different transcriptional regulatory activity. The package is implemented in R and is available under Artistic Licence 2.0 from the Bioconductor website (http://bioconductor.org/packages/FunChIP). marco.morelli@iit.it. Supplementary data are available at Bioinformatics online. © The Author (2017). Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com

Scaling Law for Cross-stream Diffusion in Microchannels under Combined Electroosmotic and Pressure Driven Flow.

PubMed

Song, Hongjun; Wang, Yi; Pant, Kapil

2013-01-01

This paper presents an analytical study of the cross-stream diffusion of an analyte in a rectangular microchannel under combined electroosmotic flow (EOF) and pressure driven flow to investigate the heterogeneous transport behavior and spatially-dependent diffusion scaling law. An analytical model capable of accurately describing 3D steady-state convection-diffusion in microchannels with arbitrary aspect ratios is developed based on the assumption of the thin Electric Double Layer (EDL). The model is verified against high-fidelity numerical simulation in terms of flow velocity and analyte concentration profiles with excellent agreement (<0.5% relative error). An extensive parametric analysis is then undertaken to interrogate the effect of the combined flow velocity field on the transport behavior in both the positive pressure gradient (PPG) and negative pressure gradient (NPG) cases. For the first time, the evolution from the spindle-shaped concentration profile in the PPG case, via the stripe-shaped profile (pure EOF), and finally to the butterfly-shaped profile in the PPG case is obtained using the analytical model along with a quantitative depiction of the spatially-dependent diffusion layer thickness and scaling law across a wide range of the parameter space.

Scaling Law for Cross-stream Diffusion in Microchannels under Combined Electroosmotic and Pressure Driven Flow

PubMed Central

Song, Hongjun; Wang, Yi; Pant, Kapil

2012-01-01

This paper presents an analytical study of the cross-stream diffusion of an analyte in a rectangular microchannel under combined electroosmotic flow (EOF) and pressure driven flow to investigate the heterogeneous transport behavior and spatially-dependent diffusion scaling law. An analytical model capable of accurately describing 3D steady-state convection-diffusion in microchannels with arbitrary aspect ratios is developed based on the assumption of the thin Electric Double Layer (EDL). The model is verified against high-fidelity numerical simulation in terms of flow velocity and analyte concentration profiles with excellent agreement (<0.5% relative error). An extensive parametric analysis is then undertaken to interrogate the effect of the combined flow velocity field on the transport behavior in both the positive pressure gradient (PPG) and negative pressure gradient (NPG) cases. For the first time, the evolution from the spindle-shaped concentration profile in the PPG case, via the stripe-shaped profile (pure EOF), and finally to the butterfly-shaped profile in the PPG case is obtained using the analytical model along with a quantitative depiction of the spatially-dependent diffusion layer thickness and scaling law across a wide range of the parameter space. PMID:23554584

The use of generalised additive models (GAM) in dentistry.

PubMed

Helfenstein, U; Steiner, M; Menghini, G

1997-12-01

Ordinary multiple regression and logistic multiple regression are widely applied statistical methods which allow a researcher to 'explain' or 'predict' a response variable from a set of explanatory variables or predictors. In these models it is usually assumed that quantitative predictors such as age enter linearly into the model. During recent years these methods have been further developed to allow more flexibility in the way explanatory variables 'act' on a response variable. The methods are called 'generalised additive models' (GAM). The rigid linear terms characterising the association between response and predictors are replaced in an optimal way by flexible curved functions of the predictors (the 'profiles'). Plotting the 'profiles' allows the researcher to visualise easily the shape by which predictors 'act' over the whole range of values. The method facilitates detection of particular shapes such as 'bumps', 'U-shapes', 'J-shapes, 'threshold values' etc. Information about the shape of the association is not revealed by traditional methods. The shapes of the profiles may be checked by performing a Monte Carlo simulation ('bootstrapping'). After the presentation of the GAM a relevant case study is presented in order to demonstrate application and use of the method. The dependence of caries in primary teeth on a set of explanatory variables is investigated. Since GAMs may not be easily accessible to dentists, this article presents them in an introductory condensed form. It was thought that a nonmathematical summary and a worked example might encourage readers to consider the methods described. GAMs may be of great value to dentists in allowing visualisation of the shape by which predictors 'act' and obtaining a better understanding of the complex relationships between predictors and response.

Prediction of Process-Induced Distortions in L-Shaped Composite Profiles Using Path-Dependent Constitutive Law

NASA Astrophysics Data System (ADS)

Ding, Anxin; Li, Shuxin; Wang, Jihui; Ni, Aiqing; Sun, Liangliang; Chang, Lei

2016-10-01

In this paper, the corner spring-in angles of AS4/8552 L-shaped composite profiles with different thicknesses are predicted using path-dependent constitutive law with the consideration of material properties variation due to phase change during curing. The prediction accuracy mainly depends on the properties in the rubbery and glassy states obtained by homogenization method rather than experimental measurements. Both analytical and finite element (FE) homogenization methods are applied to predict the overall properties of AS4/8552 composite. The effect of fiber volume fraction on the properties is investigated for both rubbery and glassy states using both methods. And the predicted results are compared with experimental measurements for the glassy state. Good agreement is achieved between the predicted results and available experimental data, showing the reliability of the homogenization method. Furthermore, the corner spring-in angles of L-shaped composite profiles are measured experimentally and the reliability of path-dependent constitutive law is validated as well as the properties prediction by FE homogenization method.

Aging and health among migrants in a European perspective.

PubMed

Kristiansen, Maria; Razum, Oliver; Tezcan-Güntekin, Hürrem; Krasnik, Allan

Population aging and the associated changes in demographic structures and healthcare needs is a key challenge across Europe. Healthy aging strategies focus on ensuring the ability to maintain health, quality of life and independent living at old age. Concurrent to the process of population aging, the demographics of Europe are affected by increased migration resulting in substantial ethnic diversity. In this paper, we narratively review the health profile of the growing proportion of aging migrants in Europe, outline key factors shaping health among this diverse group and consider ways of addressing their healthcare needs. Although factors shaping aging processes are largely similar across populations, migrant-specific risk factors exist. These include exposure to health risks before and during migration; a more disadvantaged socioeconomic position; language barriers and low health literacy; cultural factors influencing health-seeking behaviours; and psychosocial vulnerability and discrimination affecting health and quality of life. Overall, migrants experience the same morbidity and mortality causes as the native populations, but with different relative importance, severity and age of onset and with substantial differences within and between migrant groups. Little is known regarding health behaviours among aging migrants, although differences in cancer screening behaviours have been identified. Indications of widening health differentials between migrants and native populations with age and informal barriers to quality healthcare for aging migrants are causes of concern. In conclusion, there is a need for attention to migration alongside other determinants of healthy aging. The diversity in individual characteristics, life course processes and contextual factors shaping aging processes among migrants point to the need for a sensitive and comprehensive approach to policies, practices and research within the field of healthy aging. This is important to accommodate for the needs of the growing number of aging migrants in Europe and counter inequities in health and well-being at old age.

Information Processing Research

DTIC Science & Technology

1979-06-01

quantitative shape recovery. For the qualitative shape recovery we use a model of the Origami world (Kanade, 1978), together with edge profiles of...Workshop. Carnegie-Mellon University, Computer Science Department, Pittsburgh, PA, November, 1978. Kanade, T. A theory of origami world. Technical

Release profile and stability evaluation of optimized chitosan/alginate nanoparticles as EGFR antisense vector

PubMed Central

Azizi, Ebrahim; Namazi, Alireza; Haririan, Ismaeil; Fouladdel, Shamileh; Khoshayand, Mohammad R; Shotorbani, Parisa Y; Nomani, Alireza; Gazori, Taraneh

2010-01-01

Chitosan/alginate nanoparticles which had been optimized in our previous study using two different N/P ratios were chosen and their ability to release epidermal growth factor receptor (EGFR) antisense was investigated. In addition, the stability of these nanoparticles in aqueous medium and after freeze-drying was investigated. In the case of both N/P ratios (5, 25), nanoparticles started releasing EGFR antisense as soon as they were exposed to the medium and the release lasted for approximately 50 hours. Nanoparticle size, shape, zeta potential, and release profile did not show any significant change after the freeze-drying process (followed by reswelling). The nanoparticles were reswellable again after freeze-drying in phosphate buffer with a pH of 7.4 over a period of six hours. Agarose gel electrophoresis of the nanoparticles with the two different N/P ratios showed that these nanoparticles could protect EGFR antisense molecules for six hours. PMID:20957167

Omokage search: shape similarity search service for biomolecular structures in both the PDB and EMDB.

PubMed

Suzuki, Hirofumi; Kawabata, Takeshi; Nakamura, Haruki

2016-02-15

Omokage search is a service to search the global shape similarity of biological macromolecules and their assemblies, in both the Protein Data Bank (PDB) and Electron Microscopy Data Bank (EMDB). The server compares global shapes of assemblies independent of sequence order and number of subunits. As a search query, the user inputs a structure ID (PDB ID or EMDB ID) or uploads an atomic model or 3D density map to the server. The search is performed usually within 1 min, using one-dimensional profiles (incremental distance rank profiles) to characterize the shapes. Using the gmfit (Gaussian mixture model fitting) program, the found structures are fitted onto the query structure and their superimposed structures are displayed on the Web browser. Our service provides new structural perspectives to life science researchers. Omokage search is freely accessible at http://pdbj.org/omokage/. © The Author 2015. Published by Oxford University Press.

Identification and control of a multizone crystal growth furnace

NASA Technical Reports Server (NTRS)

Batur, C.; Sharpless, R. B.; Duval, W. M. B.; Rosenthal, B. N.; Singh, N. B.

1992-01-01

This paper presents an intelligent adaptive control system for the control of a solid-liquid interface of a crystal while it is growing via directional solidification inside a multizone transparent furnace. The task of the process controller is to establish a user-specified axial temperature profile and to maintain a desirable interface shape. Both single-input-single-output and multi-input-multi-output adaptive pole placement algorithms have been used to control the temperature. Also described is an intelligent measurement system to assess the shape of the crystal while it is growing. A color video imaging system observes the crystal in real time and determines the position and the shape of the interface. This information is used to evaluate the crystal growth rate, and to analyze the effects of translational velocity and temperature profiles on the shape of the interface. Creation of this knowledge base is the first step to incorporate image processing into furnace control.

Strain Measurements within Fibre Boards. Part II: Strain Concentrations at the Crack Tip of MDF Specimens Tested by the Wedge Splitting Method

PubMed Central

Sinn, Gerhard; Müller, Ulrich; Konnerth, Johannes; Rathke, Jörn

2012-01-01

This is the second part of an article series where the mechanical and fracture mechanical properties of medium density fiberboard (MDF) were studied. While the first part of the series focused on internal bond strength and density profiles, this article discusses the fracture mechanical properties of the core layer. Fracture properties were studied with a wedge splitting setup. The critical stress intensity factors as well as the specific fracture energies were determined. Critical stress intensity factors were calculated from maximum splitting force and two-dimensional isotropic finite elements simulations of the specimen geometry. Size and shape of micro crack zone were measured with electronic laser speckle interferometry. The process zone length was approx. 5 mm. The specific fracture energy was determined to be 45.2 ± 14.4 J/m2 and the critical stress intensity factor was 0.11 ± 0.02 MPa.

Continuous profiles of microstructure, stable water isotopes and impurity content of the 2m snow pack from three polar drill sites

NASA Astrophysics Data System (ADS)

Freitag, Johannes; Schaller, Christoph; Kipfstuhl, Sepp; Hörhold, Maria; Schaidt, Maximilian; Sander, Merle; Moser, Dorothea

2017-04-01

Interpreting polar ice as climate archive requires profound knowledge about the formation of climate-proxies within the upper snow column. In order to investigate different impact factors on signal formation we performed a multiproxy- approach for 2m deep snow profiles by continuously measuring the 3D-microstructure using core-scale X-CT and the isotopic composition and impurity load in discrete samples of 1.1cm spatial resolution. The study includes profiles from a low-accumulation site on the East Antarctic plateau (Kohnen Station, DML), a typical medium-accumulation site on the North-East-Greenland ice sheet (EGRIP drilling camp) and a high-accumulation site on the Renland ice cap (East-coast of Greenland, RECAP drilling camp). Major observations are the tooth-shaped imprint of structural anisotropy and sulfate concentrations at the low accumulation site, the clear isotopic inter-annual variations that are in line with distinct impurity peaks at the high-accumulation site and the unexpected missing footprint of ice crusts and refrozen melt layers within the impurity- and isotope records for all sites.

Optimization of diclofenac sodium profile from halloysite nanotubules.

PubMed

Krejčová, Kateřina; Deasy, Patrick B; Rabišková, Miloslava

2013-04-01

Halloysite, aluminosilicate clay with the particle shape of multilayered hollow nanotubes, used in various non-medical applications, e.g. in ceramic industry, was discovered for pharmaceutical purposes in recent years. Several drugs of hydrophilic and lipophilic nature have been successfully encapsulated into halloysite tubules in order to modify their dissolution profile. The main goal of this experiment was to optimize the dissolution profile of diclofenac sodium - a drug with problematic solubility - from halloysite tubules using various polymers. Loading of the drug together with povidone or Eudragit® RS did not lead to drug burst effect reduction and its slower dissolution. In the case of povidone, drug improved wettability and solubilization rather than viscosity increasing expectations were observed. Eudragit® RS formed a solid dispersion with diclofenac sodium and thus the solvent/drug solution penetration through the polymer and not the drug solubility was the dissolution rate limiting factor. Reduction of the burst effect and further prolongation of drug release was achieved by coating the drug-loaded halloysite with chitosan. This formulation exhibited a diffusion-controlled prolonged release following Higuchi kinetic model.

MAFB Determines Human Macrophage Anti-Inflammatory Polarization: Relevance for the Pathogenic Mechanisms Operating in Multicentric Carpotarsal Osteolysis.

PubMed

Cuevas, Víctor D; Anta, Laura; Samaniego, Rafael; Orta-Zavalza, Emmanuel; Vladimir de la Rosa, Juan; Baujat, Geneviève; Domínguez-Soto, Ángeles; Sánchez-Mateos, Paloma; Escribese, María M; Castrillo, Antonio; Cormier-Daire, Valérie; Vega, Miguel A; Corbí, Ángel L

2017-03-01

Macrophage phenotypic and functional heterogeneity derives from tissue-specific transcriptional signatures shaped by the local microenvironment. Most studies addressing the molecular basis for macrophage heterogeneity have focused on murine cells, whereas the factors controlling the functional specialization of human macrophages are less known. M-CSF drives the generation of human monocyte-derived macrophages with a potent anti-inflammatory activity upon stimulation. We now report that knockdown of MAFB impairs the acquisition of the anti-inflammatory profile of human macrophages, identify the MAFB-dependent gene signature in human macrophages and illustrate the coexpression of MAFB and MAFB-target genes in CD163 + tissue-resident and tumor-associated macrophages. The contribution of MAFB to the homeostatic/anti-inflammatory macrophage profile is further supported by the skewed polarization of monocyte-derived macrophages from multicentric carpotarsal osteolysis (Online Mendelian Inheritance in Man #166300), a pathology caused by mutations in the MAFB gene. Our results demonstrate that MAFB critically determines the acquisition of the anti-inflammatory transcriptional and functional profiles of human macrophages. Copyright © 2017 by The American Association of Immunologists, Inc.

Atomic oxygen in the lower thermosphere

NASA Technical Reports Server (NTRS)

Lin, Florence J.; Chance, Kelly V.; Traub, Wesley A.

1987-01-01

The 63-micron line due to thermospheric atomic oxygen O(P-3), using a far-infrared spectrometer on a balloon platform at 37 km altitude over Palestine, TX, on June 20, 1983. From measurements of the equivalent width of this line at two elevation angles, a weak angular dependence is found: the equivalent width increases by a factor of 1.5 + or - 0.3 as the angle decreases from +30 deg to +1 deg. Since the optical depth of the O(P-3) line is large, the measured line intensity cannot be directly converted to a column abundance. Instead, the measurements are interpreted in terms of radiative transfer through a 16-layer atmosphere extending to 200 km. A model atmosphere for summer at 30 deg N, with an exospheric temperature of 1300 K, including an assumed daytime atomic oxygen abundance profile constructed from recent chemical and dynamical models and a water vapor abundance profile constructed from recent experimental and model results is used. For this assumed O(P-3) vertical profile shape a multiplicative scaling factor of 0.8, with an altitude-dependent uncertainty is determined. In the best-determined layer the uncertainty in the multiplier is + or - 0.2 at 119 km. The model-dependent peak atomic oxygen density is 3.6 (+ or - 1.9) x 10 to the 11th/cu cm at an altitude of about 101 km.

Lightning Nitrogen Oxides (LNOx) Vertical Profile Quantification and 10 Year Trend Analysis using Ozone Monitoring Instrument (OMI) Satellite Measurements, Air Quality Station (AQS) Surface Measurements, The National Lightning Detection Network (NLDN), and Simulated by Cloud Resolving Chemical Transport Model (REAM Cloud)

NASA Astrophysics Data System (ADS)

Smeltzer, C. D.; Wang, Y.; Koshak, W. J.

2014-12-01

Vertical profiles and emission lifetimes of lightning nitrogen oxides (LNOx) are derived using the Ozone Monitoring Instrument (OMI). Approximately 200 million flashes, over a 10 year climate period, from the United States National Lighting Detection Network (NLDN), are aggregated with OMI cloud top height to determine the vertical LNOx structure. LNOx lifetime is determined as function of LNOx signal in a 36 kilometer vertical column from the time of the last known flash to depletion of the LNOx signal. Environmental Protection Agency (EPA) Air Quality Station (AQS) surface data further support these results by demonstrating as much as a 200% increase in surface level NO2 during strong thunderstorm events and a lag as long as 5 to 8 hours from the lightning event to the peak surface event, indicating a evolutional process. Analysis of cloud resolving chemical transport model (REAM Cloud) demonstrates that C-shaped LNOx profiles, which agree with OMI vertical profile observations, evolve due to micro-scale convective meteorology given inverted C-shaped LNOx emission profiles as determined from lightning radio telemetry. It is shown, both in simulations and in observations, that the extent to which the LNOx vertical distribution is C-shaped and the lifetime of LNOx is proportional to the shear-strength of the thunderstorm. Micro-scale convective meteorology is not adequately parameterized in global scale and regional scale chemical transport models (CTM). Therefore, these larger scale CTMs ought to use a C-shape emissions profile to best reproduce observations until convective parameterizations are updated. These findings are used to simulate decadal LNOx and lightning ozone climatology over the Continental United States (CONUS) from 2004-2014.

Simple Parametric Model for Airfoil Shape Description

NASA Astrophysics Data System (ADS)

Ziemkiewicz, David

2017-12-01

We show a simple, analytic equation describing a class of two-dimensional shapes well suited for representation of aircraft airfoil profiles. Our goal was to create a description characterized by a small number of parameters with easily understandable meaning, providing a tool to alter the shape with optimization procedures as well as manual tweaks by the designer. The generated shapes are well suited for numerical analysis with 2D flow solving software such as XFOIL.

Field mappers for laser material processing

NASA Astrophysics Data System (ADS)

Blair, Paul; Currie, Matthew; Trela, Natalia; Baker, Howard J.; Murphy, Eoin; Walker, Duncan; McBride, Roy

2016-03-01

The native shape of the single-mode laser beam used for high power material processing applications is circular with a Gaussian intensity profile. Manufacturers are now demanding the ability to transform the intensity profile and shape to be compatible with a new generation of advanced processing applications that require much higher precision and control. We describe the design, fabrication and application of a dual-optic, beam-shaping system for single-mode laser sources, that transforms a Gaussian laser beam by remapping - hence field mapping - the intensity profile to create a wide variety of spot shapes including discs, donuts, XY separable and rotationally symmetric. The pair of optics transform the intensity distribution and subsequently flatten the phase of the beam, with spot sizes and depth of focus close to that of a diffraction limited beam. The field mapping approach to beam-shaping is a refractive solution that does not add speckle to the beam, making it ideal for use with single mode laser sources, moving beyond the limits of conventional field mapping in terms of spot size and achievable shapes. We describe a manufacturing process for refractive optics in fused silica that uses a freeform direct-write process that is especially suited for the fabrication of this type of freeform optic. The beam-shaper described above was manufactured in conventional UV-fused silica using this process. The fabrication process generates a smooth surface (<1nm RMS), leading to laser damage thresholds of greater than 100J/cm2, which is well matched to high power laser sources. Experimental verification of the dual-optic filed mapper is presented.

Laser beam shaping for studying thermally induced damage

NASA Astrophysics Data System (ADS)

Masina, Bathusile N.; Bodkin, Richard; Mwakikunga, Bonex; Forbes, Andrew

2011-10-01

This paper presents an implementation of a laser beam shaping system for both heating a diamond tool and measuring the resulting temperature optically. The influence the initial laser parameters have on the resultant temperature profiles is shown experimentally and theoretically. A CO2 laser beam was used as the source to raise the temperature of the diamond tool and the resultant temperature was measured by using the blackbody principle. We have successfully transformed a Gaussian beam profile into a flat-top beam profile by using a diffractive optical element as a phase element in conjunction with a Fourier transforming lens. In this paper, we have successfully demonstrated temperature profiles across the diamond tool surface using two laser beam profiles and two optical setups, thus allowing a study of temperature influences with and without thermal stress. The generation of such temperature profiles on the diamond tool in the laboratory is important in the study of changes that occur in diamond tools, particularly the reduced efficiency of such tools in applications where extreme heating due to friction is expected.

Meniscus on a shaped fibre: singularities and hodograph formulation.

PubMed

Alimov, Mars M; Kornev, Konstantin G

2014-08-08

Using the method of matched asymptotic expansions, the problem of the capillary rise of a meniscus on the complex-shaped fibres was reduced to a nonlinear problem of determination of a minimal surface. This surface has to satisfy a special boundary condition at infinity. The proposed formulation allows one to interpret the meniscus problem as a problem of flow of a fictitious non-Newtonian fluid through a porous medium. As an example, the shape of a meniscus on a fibre of an oval cross section was analysed employing Chaplygin's hodograph transformation. It was discovered that the contact line may form singularities even if the fibre has a smooth profile: this statement was illustrated with an oval fibre profile having infinite curvature at two endpoints.

Meniscus on a shaped fibre: singularities and hodograph formulation

PubMed Central

Alimov, Mars M.; Kornev, Konstantin G.

2014-01-01

Using the method of matched asymptotic expansions, the problem of the capillary rise of a meniscus on the complex-shaped fibres was reduced to a nonlinear problem of determination of a minimal surface. This surface has to satisfy a special boundary condition at infinity. The proposed formulation allows one to interpret the meniscus problem as a problem of flow of a fictitious non-Newtonian fluid through a porous medium. As an example, the shape of a meniscus on a fibre of an oval cross section was analysed employing Chaplygin's hodograph transformation. It was discovered that the contact line may form singularities even if the fibre has a smooth profile: this statement was illustrated with an oval fibre profile having infinite curvature at two endpoints. PMID:25104910

Life satisfaction and age: Dealing with underidentification in age-period-cohort models.

PubMed

de Ree, Joppe; Alessie, Rob

2011-07-01

Recent literature typically finds a U shaped relationship between life satisfaction and age. Age profiles, however, are not identified without forcing arbitrary restrictions on the cohort and/or time profiles. In this paper we report what can be identified about the relationship between life satisfaction and age without applying such restrictions. Also, we identify the restrictions needed to conclude that life satisfaction is U shaped in age. For the case of Germany, we find that the relationship between life satisfaction and age is indeed U shaped, but only under the untestable condition that the linear time trend is negative and that the linear trend across birth cohorts is practically flat. Copyright © 2011 Elsevier Ltd. All rights reserved.

Optical fiber designs for beam shaping

NASA Astrophysics Data System (ADS)

Farley, Kevin; Conroy, Michael; Wang, Chih-Hao; Abramczyk, Jaroslaw; Campbell, Stuart; Oulundsen, George; Tankala, Kanishka

2014-03-01

A large number of power delivery applications for optical fibers require beams with very specific output intensity profiles; in particular applications that require a focused high intensity beam typically image the near field (NF) intensity distribution at the exit surface of an optical fiber. In this work we discuss optical fiber designs that shape the output beam profile to more closely correspond to what is required in many real world industrial applications. Specifically we present results demonstrating the ability to transform Gaussian beams to shapes required for industrial applications and how that relates to system parameters such as beam product parameter (BPP) values. We report on the how different waveguide structures perform in the NF and show results on how to achieve flat-top with circular outputs.

Genome-wide organization and expression profiling of the NAC transcription factor family in potato (Solanum tuberosum L.).

PubMed

Singh, Anil Kumar; Sharma, Vishal; Pal, Awadhesh Kumar; Acharya, Vishal; Ahuja, Paramvir Singh

2013-08-01

NAC [no apical meristem (NAM), Arabidopsis thaliana transcription activation factor [ATAF1/2] and cup-shaped cotyledon (CUC2)] proteins belong to one of the largest plant-specific transcription factor (TF) families and play important roles in plant development processes, response to biotic and abiotic cues and hormone signalling. Our genome-wide analysis identified 110 StNAC genes in potato encoding for 136 proteins, including 14 membrane-bound TFs. The physical map positions of StNAC genes on 12 potato chromosomes were non-random, and 40 genes were found to be distributed in 16 clusters. The StNAC proteins were phylogenetically clustered into 12 subgroups. Phylogenetic analysis of StNACs along with their Arabidopsis and rice counterparts divided these proteins into 18 subgroups. Our comparative analysis has also identified 36 putative TNAC proteins, which appear to be restricted to Solanaceae family. In silico expression analysis, using Illumina RNA-seq transcriptome data, revealed tissue-specific, biotic, abiotic stress and hormone-responsive expression profile of StNAC genes. Several StNAC genes, including StNAC072 and StNAC101that are orthologs of known stress-responsive Arabidopsis RESPONSIVE TO DEHYDRATION 26 (RD26) were identified as highly abiotic stress responsive. Quantitative real-time polymerase chain reaction analysis largely corroborated the expression profile of StNAC genes as revealed by the RNA-seq data. Taken together, this analysis indicates towards putative functions of several StNAC TFs, which will provide blue-print for their functional characterization and utilization in potato improvement.

Aerodynamic analysis of the Darrieus rotor including secondary effects

NASA Astrophysics Data System (ADS)

Paraschivoiu, I.; Delclaux, F.; Fraunie, P.; Beguier, C.

1983-10-01

An aerodynamic analysis is made of two variants of the two-actuator-disk theory for modeling the Darrieus wind turbine. The double-multiple-streamtube model with constant and variable interference factors, including secondary effects, is examined for a Darrieus rotor. The influence of the secondary effects, namely, the blade geometry and profile type, the rotating tower, and the presence of struts and aerodynamic spoilers, is relatively significant, especially at high tip-speed ratios. Variation of the induced velocity as a function of the azimuthal angle allows a more accurate calculation of the aerodynamic loads on the downwind zone of the rotor with respect to the assumed constant interference factors. The theoretical results were compared with available experimental data for the Magdalen Islands wind turbine and Sandia-type machines (straight-line/circular-arc shape).

Accumulation and diagenesis of chlorinated hydrocarbons in lacustrine sediments

USGS Publications Warehouse

Elsenreich, S.J.; Capel, P.D.; Robbins, J.A.; Bourbonniere, R.

1989-01-01

Two sediment cores were taken from the Rochester Basin of eastern Lake Ontario and analyzed for the radionuclides 210Pb and 137Cs and several high molecular weight chlorinated hydrocarbons (CHs). The two sites are geographically proximate but differ in sedimentation rate, permitting sedimentation-dependent processes to be factored out. The 210Pb chronology showed a mixed depth of 3-5 cm and an intrinsic time resolution of 11-14 years. Vertically integrated numbers of deposit-feeding oligochaete worms and burrowing organisms are insufficient to homogenize the sediment on the time scale of CH inputs, which are non steady state. U.S. production and sales of polychlorinated biphenyls (PCBs), DDT, Mirex, and hexachlorobenzene (HCB), as determinants of the shape of the input function, adequately predict the overall shape and, in many cases, details in the sedimentary profile. Sediment focusing factors (FF) inferred from 137Cs and 210Pb inventories averaged 1.17 and 1.74 for cores E-30 and G-32, respectively. This permitted CH accumulation rates to be corrected for focusing. Apparent molecular diffusion coefficients modeled for many of the CHs were about (1-3) ?? 10-9 cm2/s.

X-RAY EMISSION LINE PROFILES FROM WIND CLUMP BOW SHOCKS IN MASSIVE STARS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ignace, R.; Waldron, W. L.; Cassinelli, J. P.

2012-05-01

The consequences of structured flows continue to be a pressing topic in relating spectral data to physical processes occurring in massive star winds. In a preceding paper, our group reported on hydrodynamic simulations of hypersonic flow past a rigid spherical clump to explore the structure of bow shocks that can form around wind clumps. Here we report on profiles of emission lines that arise from such bow shock morphologies. To compute emission line profiles, we adopt a two-component flow structure of wind and clumps using two 'beta' velocity laws. While individual bow shocks tend to generate double-horned emission line profiles,more » a group of bow shocks can lead to line profiles with a range of shapes with blueshifted peak emission that depends on the degree of X-ray photoabsorption by the interclump wind medium, the number of clump structures in the flow, and the radial distribution of the clumps. Using the two beta law prescription, the theoretical emission measure and temperature distribution throughout the wind can be derived. The emission measure tends to be power law, and the temperature distribution is broad in terms of wind velocity. Although restricted to the case of adiabatic cooling, our models highlight the influence of bow shock effects for hot plasma temperature and emission measure distributions in stellar winds and their impact on X-ray line profile shapes. Previous models have focused on geometrical considerations of the clumps and their distribution in the wind. Our results represent the first time that the temperature distribution of wind clump structures are explicitly and self-consistently accounted for in modeling X-ray line profile shapes for massive stars.« less

Investigation on Convergence – Divergence Nozzle Shape for Microscale Channel in Harvesting Kinetic Energy

NASA Astrophysics Data System (ADS)

Zakaria, M. S.; Zairi, S.; Misbah, M. N.; Saifizi, M.; Rakawi, Izzudin

2018-03-01

This paper presents performance evaluation of nozzle shapes on microscale channel by employing different types of NACA airfoils profile and conventional profile. The deploying nozzle used are NACA 0012, NACA 0021 and NACA 0024 airfoils while for conventional convergence-divergence nozzle diameter ratio (d2 / d1) in the range from 1/4 to 3/4 are applied. These nozzles are assembled on rectangular cross sectional microscale channel which has designated constant fluid flow velocity at the channel inlet. This study revealed reduction on diameter ratio increased dramatically fluid velocity but further reduction on diameter ratio exposed fluid flow to fluctuate which slightly slowing down the fluid velocity. Nevertheless, curved NACA profiles are favourable for convergence – divergence nozzle in microscale channel as it significantly improved flow characteristics by enhancing fluid velocity and resultant kinetic energy as compared to conventional profile.

First-passage dynamics of linear stochastic interface models: weak-noise theory and influence of boundary conditions

NASA Astrophysics Data System (ADS)

Gross, Markus

2018-03-01

We consider a one-dimensional fluctuating interfacial profile governed by the Edwards–Wilkinson or the stochastic Mullins-Herring equation for periodic, standard Dirichlet and Dirichlet no-flux boundary conditions. The minimum action path of an interfacial fluctuation conditioned to reach a given maximum height M at a finite (first-passage) time T is calculated within the weak-noise approximation. Dynamic and static scaling functions for the profile shape are obtained in the transient and the equilibrium regime, i.e. for first-passage times T smaller or larger than the characteristic relaxation time, respectively. In both regimes, the profile approaches the maximum height M with a universal algebraic time dependence characterized solely by the dynamic exponent of the model. It is shown that, in the equilibrium regime, the spatial shape of the profile depends sensitively on boundary conditions and conservation laws, but it is essentially independent of them in the transient regime.

Surface Profile and Stress Field Evaluation using Digital Gradient Sensing Method

DOE PAGES

Miao, C.; Sundaram, B. M.; Huang, L.; ...

2016-08-09

Shape and surface topography evaluation from measured orthogonal slope/gradient data is of considerable engineering significance since many full-field optical sensors and interferometers readily output accurate data of that kind. This has applications ranging from metrology of optical and electronic elements (lenses, silicon wafers, thin film coatings), surface profile estimation, wave front and shape reconstruction, to name a few. In this context, a new methodology for surface profile and stress field determination based on a recently introduced non-contact, full-field optical method called digital gradient sensing (DGS) capable of measuring small angular deflections of light rays coupled with a robust finite-difference-based least-squaresmore » integration (HFLI) scheme in the Southwell configuration is advanced here. The method is demonstrated by evaluating (a) surface profiles of mechanically warped silicon wafers and (b) stress gradients near growing cracks in planar phase objects.« less

Cold spraying of aluminum bronze on profiled submillimeter cermet structures formed by laser cladding

NASA Astrophysics Data System (ADS)

Ryashin, N. S.; Malikov, A. G.; Shikalov, V. S.; Gulyaev, I. P.; Kuchumov, B. M.; Klinkov, S. V.; Kosarev, V. F.; Orishich, A. M.

2017-10-01

The paper presents results of the cold spraying of aluminum bronze coatings on substrates profiled with WC/Ni tracks obtained by laser cladding. Reinforcing cermet frames shaped as grids with varied mesh sizes were clad on stainless steel substrates using a CO2 laser machine "Siberia" (ITAM SB RAS, Russia). As a result, surfaces/substrates with heterogeneous shape, composition, and mechanical properties were obtained. Aluminum bronze coatings were deposited from 5lF-NS powder (Oerlikon Metco, Switzerland) on those substrates using cold spraying equipment (ITAM SB RAS). Data of profiling, microstructure diagnostics, EDS analysis, and mechanical tests of obtained composites is reported. Surface relief of the sprayed coatings dependence on substrate structure has been demonstrated.

Experimental Profiling of a Non-truncated Focused Gaussian Beam and Fine-tuning of the Quadratic Phase in the Fresnel Gaussian Shape Invariant

DOE Office of Scientific and Technical Information (OSTI.GOV)

S., Juan Manuel Franco; Cywiak, Moises; Cywiak, David

2015-06-24

A homodyne profiler is used for recording the intensity distribution of focused non-truncated Gaussian beams. The spatial distributions are obtained at planes in the vicinity of the back-focal plane of a focusing lens placed at different distances from a He–Ne laser beam with a Gaussian intensity profile. Comparisons of the experimental data with those obtained from the analytical equations for an ideal focusing lens allow us to propose formulae to fine-tune the quadratic term in the Fresnel Gaussian shape invariant at each interface of the propagated field. Furthermore, we give analytical expressions to calculate adequately the propagation of the fieldmore » through an optical system.« less

An examination of flame shape related to convection heat transfer in deep-fuel beds

Treesearch

Kara M. Yedinak; Jack D. Cohen; Jason M. Forthofer; Mark A. Finney

2010-01-01

Fire spread through a fuel bed produces an observable curved combustion interface. This shape has been schematically represented largely without consideration for fire spread processes. The shape and dynamics of the flame profile within the fuel bed likely reflect the mechanisms of heat transfer necessary for the pre-heating and ignition of the fuel during fire spread....

Impact of initial pulse shape on the nonlinear spectral compression in optical fibre

NASA Astrophysics Data System (ADS)

Boscolo, Sonia; Chaussard, Frederic; Andresen, Esben; Rigneault, Hervé; Finot, Christophe

2018-02-01

We theoretically study the effects of the temporal intensity profile of the initial pulse on the nonlinear propagation spectral compression process arising from nonlinear propagation in an optical fibre. Various linearly chirped input pulse profiles are considered, and their dynamics is explained with the aid of time-frequency representations. While initially parabolic-shaped pulses show enhanced spectral compression compared to Gaussian pulses, no significant spectral narrowing occurs when initially super-Gaussian pulses are used. Triangular pulses lead to a spectral interference phenomenon similar to the Fresnel bi-prism experiment.

Mirror Measurement Device

NASA Technical Reports Server (NTRS)

1992-01-01

A Small Business Innovation Research (SBIR) contract led to a commercially available instrument used to measure the shape profile of mirror surfaces in scientific instruments. Bauer Associates, Inc.'s Bauer Model 200 Profilometer is based upon a different measurement concept. The local curvature of the mirror's surface is measured at many points, and the collection of data is computer processed to yield the desired shape profile. (Earlier profilometers are based on the principle of interferometry.) The system is accurate and immune to problems like vibration and turbulence. Two profilometers are currently marketed, and a third will soon be commercialized.

Volatile-rich Crater Interior Deposits on Mars: An Energy Balance Model of Modification

NASA Technical Reports Server (NTRS)

Russell, Patrick S.; Head, James W.; Hecht, Michael H.

2003-01-01

Several craters on Mars are partially filled by material emplaced by post-impact processes. Populations of such craters include those in the circumsouth polar cap region, in Arabia Terra, associated with the Medusae Fossae Formation, and in the northern lowlands proximal to the north polar cap. In this study, crater fill material refers to an interior mound, generally separated from the interior walls of the crater by a trough that may be continuous along the crater s circumference (i.e. a ring-shaped trough), or may only partially contact the crater walls (i.e. a crescent-shaped trough). The fill deposit is frequently off-center from the crater center and may be asymmetric, (i.e. not circular) in plan view shape. Here we test the hypothesis that asymmetries in volatile fill shape, profile, and center-location within a crater result from asymmetries in local energy balance within the crater due mainly to variation of solar insolation and radiative effects of the crater walls over the crater interior. We first focus on Korolev crater in the northern lowlands. We can then apply this model to other craters in different regions. If asymmetry in morphology and location of crater fill are consistent with radiative-dominated asymmetries in energy budget within the crater, then 1) the volatile-rich composition of the fill is supported (this process should not be effective at shaping volcanic or sedimentary deposits), and 2) the dominant factor determining the observed shape of volatile-rich crater fill is the local radiative energy budget within the crater (and erosive processes such as eolian deflation are not necessary).

Fast automatic 3D liver segmentation based on a three-level AdaBoost-guided active shape model

DOE Office of Scientific and Technical Information (OSTI.GOV)

He, Baochun; Huang, Cheng; Zhou, Shoujun

Purpose: A robust, automatic, and rapid method for liver delineation is urgently needed for the diagnosis and treatment of liver disorders. Until now, the high variability in liver shape, local image artifacts, and the presence of tumors have complicated the development of automatic 3D liver segmentation. In this study, an automatic three-level AdaBoost-guided active shape model (ASM) is proposed for the segmentation of the liver based on enhanced computed tomography images in a robust and fast manner, with an emphasis on the detection of tumors. Methods: The AdaBoost voxel classifier and AdaBoost profile classifier were used to automatically guide three-levelmore » active shape modeling. In the first level of model initialization, fast automatic liver segmentation by an AdaBoost voxel classifier method is proposed. A shape model is then initialized by registration with the resulting rough segmentation. In the second level of active shape model fitting, a prior model based on the two-class AdaBoost profile classifier is proposed to identify the optimal surface. In the third level, a deformable simplex mesh with profile probability and curvature constraint as the external force is used to refine the shape fitting result. In total, three registration methods—3D similarity registration, probability atlas B-spline, and their proposed deformable closest point registration—are used to establish shape correspondence. Results: The proposed method was evaluated using three public challenge datasets: 3Dircadb1, SLIVER07, and Visceral Anatomy3. The results showed that our approach performs with promising efficiency, with an average of 35 s, and accuracy, with an average Dice similarity coefficient (DSC) of 0.94 ± 0.02, 0.96 ± 0.01, and 0.94 ± 0.02 for the 3Dircadb1, SLIVER07, and Anatomy3 training datasets, respectively. The DSC of the SLIVER07 testing and Anatomy3 unseen testing datasets were 0.964 and 0.933, respectively. Conclusions: The proposed automatic approach achieves robust, accurate, and fast liver segmentation for 3D CTce datasets. The AdaBoost voxel classifier can detect liver area quickly without errors and provides sufficient liver shape information for model initialization. The AdaBoost profile classifier achieves sufficient accuracy and greatly decreases segmentation time. These results show that the proposed segmentation method achieves a level of accuracy comparable to that of state-of-the-art automatic methods based on ASM.« less

Fast automatic 3D liver segmentation based on a three-level AdaBoost-guided active shape model.

PubMed

He, Baochun; Huang, Cheng; Sharp, Gregory; Zhou, Shoujun; Hu, Qingmao; Fang, Chihua; Fan, Yingfang; Jia, Fucang

2016-05-01

A robust, automatic, and rapid method for liver delineation is urgently needed for the diagnosis and treatment of liver disorders. Until now, the high variability in liver shape, local image artifacts, and the presence of tumors have complicated the development of automatic 3D liver segmentation. In this study, an automatic three-level AdaBoost-guided active shape model (ASM) is proposed for the segmentation of the liver based on enhanced computed tomography images in a robust and fast manner, with an emphasis on the detection of tumors. The AdaBoost voxel classifier and AdaBoost profile classifier were used to automatically guide three-level active shape modeling. In the first level of model initialization, fast automatic liver segmentation by an AdaBoost voxel classifier method is proposed. A shape model is then initialized by registration with the resulting rough segmentation. In the second level of active shape model fitting, a prior model based on the two-class AdaBoost profile classifier is proposed to identify the optimal surface. In the third level, a deformable simplex mesh with profile probability and curvature constraint as the external force is used to refine the shape fitting result. In total, three registration methods-3D similarity registration, probability atlas B-spline, and their proposed deformable closest point registration-are used to establish shape correspondence. The proposed method was evaluated using three public challenge datasets: 3Dircadb1, SLIVER07, and Visceral Anatomy3. The results showed that our approach performs with promising efficiency, with an average of 35 s, and accuracy, with an average Dice similarity coefficient (DSC) of 0.94 ± 0.02, 0.96 ± 0.01, and 0.94 ± 0.02 for the 3Dircadb1, SLIVER07, and Anatomy3 training datasets, respectively. The DSC of the SLIVER07 testing and Anatomy3 unseen testing datasets were 0.964 and 0.933, respectively. The proposed automatic approach achieves robust, accurate, and fast liver segmentation for 3D CTce datasets. The AdaBoost voxel classifier can detect liver area quickly without errors and provides sufficient liver shape information for model initialization. The AdaBoost profile classifier achieves sufficient accuracy and greatly decreases segmentation time. These results show that the proposed segmentation method achieves a level of accuracy comparable to that of state-of-the-art automatic methods based on ASM.

Eliminating the influence of source spectrum of white light scanning interferometry through time-delay estimation algorithm

NASA Astrophysics Data System (ADS)

Zhou, Yunfei; Cai, Hongzhi; Zhong, Liyun; Qiu, Xiang; Tian, Jindong; Lu, Xiaoxu

2017-05-01

In white light scanning interferometry (WLSI), the accuracy of profile measurement achieved with the conventional zero optical path difference (ZOPD) position locating method is closely related with the shape of interference signal envelope (ISE), which is mainly decided by the spectral distribution of illumination source. For a broadband light with Gaussian spectral distribution, the corresponding shape of ISE reveals a symmetric distribution, so the accurate ZOPD position can be achieved easily. However, if the spectral distribution of source is irregular, the shape of ISE will become asymmetric or complex multi-peak distribution, WLSI cannot work well through using ZOPD position locating method. Aiming at this problem, we propose time-delay estimation (TDE) based WLSI method, in which the surface profile information is achieved by using the relative displacement of interference signal between different pixels instead of the conventional ZOPD position locating method. Due to all spectral information of interference signal (envelope and phase) are utilized, in addition to revealing the advantage of high accuracy, the proposed method can achieve profile measurement with high accuracy in the case that the shape of ISE is irregular while ZOPD position locating method cannot work. That is to say, the proposed method can effectively eliminate the influence of source spectrum.

Investigation of the effect of tablet surface area/volume on drug release from hydroxypropylmethylcellulose controlled-release matrix tablets.

PubMed

Reynolds, Thomas D; Mitchell, Shawn A; Balwinski, Karen M

2002-04-01

The purpose of this study was to investigate the influence of tablet surface area/volume (SA/Vol) on drug release from controlled-release matrix tablets containing hydroxypropylmethylcellulose (HPMC). Soluble drugs (promethazine HCl, diphenhydramine HCl, and propranolol HCl) were utilized in this study to give predominantly diffusion-controlled release. Drug release from HPMC matrix tablets with similar values of SA/Vol was comparable within the same tablet shape (i.e., flat-faced round tablets) and among different shapes (i.e., oval, round concave, flat-faced beveled-edge, and flat-faced round tablets). Tablets having the same surface area but different SA/Vol values did not result in similar drug release; tablets with larger SA/Vol values hadfaster release profiles. Utility of SA/Vol to affect drug release was demonstrated by changing drug doses, and altering tablet shape to adjust SA/Vol. When SA/Vol was held constant, similar release profiles were obtained with f2 metric values greater than 70. Thus, surface area/volume is one of the key variables in controlling drug release from HPMC matrix tablets. Proper use of this variable has practical application by formulators who may need to duplicate drug release profiles from tablets of different sizes and different shapes.

Minimum magnetic curvature for resilient divertors using Compact Toroidal Hybrid geometry

DOE PAGES

Bader, Aaron; Hegna, C. C.; Cianciosa, Mark R.; ...

2018-03-16

The properties of resilient divertors are explored using equilibria derived from Compact Toroidal Hybrid (CTH) geometries. Resilience is defined here as the robustness of the strike point patterns as the plasma geometry and/or plasma profiles are changed. The addition of plasma current in the CTH configurations significantly alters the shape of the last closed flux surface and the rotational transform profile, however, it does not alter the strike point pattern on the target plates, and hence has resilient divertor features. The limits of when a configuration transforms to a resilient configuration is then explored. New CTH-like configurations are generated thatmore » vary from a perfectly circular cross section to configurations with increasing amounts of toroidal shaping. It is found that even small amounts of toroidal shaping lead to strike point localization that is similar to the standard CTH configuration. Lastly, these results show that only a small degree of three-dimensional shaping is necessary to produce a resilient divertor, implying that any highly shaped optimized stellarator will possess the resilient divertor property.« less

Shape design of internal cooling passages within a turbine blade

NASA Astrophysics Data System (ADS)

Nowak, Grzegorz; Nowak, Iwona

2012-04-01

The article concerns the optimization of the shape and location of non-circular passages cooling the blade of a gas turbine. To model the shape, four Bezier curves which form a closed profile of the passage were used. In order to match the shape of the passage to the blade profile, a technique was put forward to copy and scale the profile fragments into the component, and build the outline of the passage on the basis of them. For so-defined cooling passages, optimization calculations were carried out with a view to finding their optimal shape and location in terms of the assumed objectives. The task was solved as a multi-objective problem with the use of the Pareto method, for a cooling system composed of four and five passages. The tool employed for the optimization was the evolutionary algorithm. The article presents the impact of the population on the task convergence, and discusses the impact of different optimization objectives on the Pareto optimal solutions obtained. Due to the problem of different impacts of individual objectives on the position of the solution front which was noticed during the calculations, a two-step optimization procedure was introduced. Also, comparative optimization calculations for the scalar objective function were carried out and set up against the non-dominated solutions obtained in the Pareto approach. The optimization process resulted in a configuration of the cooling system that allows a significant reduction in the temperature of the blade and its thermal stress.

An algorithm for selecting the most accurate protocol for contact angle measurement by drop shape analysis.

PubMed

Xu, Z N

2014-12-01

In this study, an error analysis is performed to study real water drop images and the corresponding numerically generated water drop profiles for three widely used static contact angle algorithms: the circle- and ellipse-fitting algorithms and the axisymmetric drop shape analysis-profile (ADSA-P) algorithm. The results demonstrate the accuracy of the numerically generated drop profiles based on the Laplace equation. A significant number of water drop profiles with different volumes, contact angles, and noise levels are generated, and the influences of the three factors on the accuracies of the three algorithms are systematically investigated. The results reveal that the above-mentioned three algorithms are complementary. In fact, the circle- and ellipse-fitting algorithms show low errors and are highly resistant to noise for water drops with small/medium volumes and contact angles, while for water drop with large volumes and contact angles just the ADSA-P algorithm can meet accuracy requirement. However, this algorithm introduces significant errors in the case of small volumes and contact angles because of its high sensitivity to noise. The critical water drop volumes of the circle- and ellipse-fitting algorithms corresponding to a certain contact angle error are obtained through a significant amount of computation. To improve the precision of the static contact angle measurement, a more accurate algorithm based on a combination of the three algorithms is proposed. Following a systematic investigation, the algorithm selection rule is described in detail, while maintaining the advantages of the three algorithms and overcoming their deficiencies. In general, static contact angles over the entire hydrophobicity range can be accurately evaluated using the proposed algorithm. The ease of erroneous judgment in static contact angle measurements is avoided. The proposed algorithm is validated by a static contact angle evaluation of real and numerically generated water drop images with different hydrophobicity values and volumes.

Determination of the vinyl fluoride line intensities by TDL spectroscopy: the object oriented approach of Visual Line Shape Fitting Program to line profile analysis

NASA Astrophysics Data System (ADS)

Tasinato, Nicola; Pietropolli Charmet, Andrea; Stoppa, Paolo; Giorgianni, Santi

2010-03-01

In this work the self-broadening coefficients and the integrated line intensities for a number of ro-vibrational transitions of vinyl fluoride have been determined for the first time by means of TDL spectroscopy. The spectra recorded in the atmospheric window around 8.7 µm appear very crowded with a density of about 90 lines per cm-1. In order to fit these spectral features a new fitting software has been implemented. The program, which is designed for laser spectroscopy, can fit many lines simultaneously on the basis of different theoretical profiles (Doppler, Lorentz, Voigt, Galatry and Nelkin-Ghatak). Details of the object oriented implementation of the application are given. The reliability of the program is demonstrated by determining the line parameters of some ro-vibrational lines of sulphur dioxide in the ν1 band region around 9 µm. Then the software is used for the line profile analysis of vinyl fluoride. The experimental line shapes show deviations from the Voigt profile, which can be well modelled by using a Dicke narrowed line shape function. This leads to the determination of the self-narrowing coefficient within the framework of the strong collision model.

Shaping Cutter Original Profile for Fine-module Ratchet Teeth Cutting

NASA Astrophysics Data System (ADS)

Sharkov, O. V.; Koryagin, S. I.; Velikanov, N. L.

2018-03-01

The methods for determining geometric characteristics of a theoretical original profile of the cutter for cutting ratchet teeth with a module of 0.3–1.0 mm are considered in the article. Design models describing the shaping process of cutting edges of cutter teeth are developed. Systems of expressions for determining coordinates of the points of front and back edges of cutter teeth; the workpiece angles of rotation during the cutting process; the minimum cutter radius are received. The basic data when using the proposed technique are: radii of circumferences passing through cavities of cutter teeth and external cut teeth; the gradient angle and length of straight section of the front edge of a cut tooth; angles of rotation of the cutter and the workpiece at the moment of shaping.

Phenotypic Plasticity of Cuticular Hydrocarbon Profiles in Insects.

PubMed

Otte, Tobias; Hilker, Monika; Geiselhardt, Sven

2018-03-01

The insect integument is covered by cuticular hydrocarbons (CHCs) which provide protection against environmental stresses, but are also used for communication. Here we review current knowledge on environmental and insect-internal factors which shape phenotypic plasticity of solitary living insects, especially herbivorous ones. We address the dynamics of changes which may occur within minutes, but may also last weeks, depending on the species and conditions. Two different modes of changes are suggested, i.e. stepwise and gradual. A switch between two distinct environments (e.g. host plant switch by phytophagous insects) results in stepwise formation of two distinct adaptive phenotypes, while a gradual environmental change (e.g. temperature gradients) induces a gradual change of numerous adaptive CHC phenotypes. We further discuss the ecological and evolutionary consequences of phenotypic plasticity of insect CHC profiles by addressing the question at which conditions is CHC phenotypic plasticity beneficial. The high plasticity of CHC profiles might be a trade-off for insects using CHCs for communication. We discuss how insects cope with the challenge to produce and "understand" a highly plastic, environmentally dependent CHC pattern that conveys reliable and comprehensible information. Finally, we outline how phenotypic plasticity of CHC profiles may promote speciation in insects that rely on CHCs for mate recognition.

Shape and Construction of Brick Vaults. Criteria, Methods and Tools for a Possible Catalogue

NASA Astrophysics Data System (ADS)

Brumana, R.; Condoleo, P.; Grimoldi, A.; Landi, A. G.

2017-05-01

The use of cloister vaults in the construction of noble buildings, as covering elements for square or rectangular rooms, is widespread and well-known. The geometric continuity at the intrados makes generally possible the execution all over the span of frescoes, stucco and decorations. The construction of brick vaults, from the late Middle Age, was sped up by limiting the centering to the wooden planks arches that were instrumental in the profile determination. Nowadays, the availability of several procedures, phases and tools for carrying out a survey allows to draw reliable assumptions about the construction methods and the execution time. It is mandatory to determine the properties of the binders, the shape and dimensions of the bricks, and to carry out a comparison between the geometry of the intrados surface and the evidences emerging at the extrados. The support of the laser scanner technique allows to accurately identify the surface profile and thickness. All these indications, in turn, are useful, in view of an interpretation of the structural behavior, to identify weaknesses, and to highlight contributing factors of instability (if any). The paper focuses on a well-documented case, the Magio Grasselli palace in Cremona in which the cloister vaults of two main rooms show different construction systems, although they were built almost at the same time. The thermographic recordings and laser-scanner surveys highlight the various arrangements used for the cloister vaults.

Structure of star-burst dendrimers: a comparison between small angle x-ray scattering and computer simulation results.

PubMed

Rathgeber, Silke; Pakula, Tadeusz; Urban, Volker

2004-08-22

We investigated the generation dependent shape and internal structure of star-burst dendrimers under good solvent conditions using small angle x-ray scattering and molecular modeling. Measurements have been performed on poly(amidoamine) dendrimers with generations ranging from g=0 up to g=8 at low concentrations in methanol. We described the static form factor P(q) by a model taking into account the compact, globular shape as well as the loose, polymeric character of dendrimers. Monomer distributions within dendrimers are of special interest for potential applications and have been characterized by the pair correlation function gamma(r), as well as by the monomer and end-group density profile, rho(r) and rho(e)(r), respectively. Monomer density profiles and gamma(r) can be derived from P(q) by modeling and via a model independent approach using the inverse Fourier transformation algorithm first introduced by Glatter. Experimental results are compared with computer simulations performed for single dendrimers of various generations using the cooperative motion algorithm. The simulation gives direct access to gamma(r) and rho(r), allows an independent determination of P(q), and yields in addition to the scattering experiment information about the distribution of the end groups. Excellent qualitative agreement between experiment and simulation has been found. (c) 2004 American Institute of Physics

Characterization of plasma parameters in shaped PBX-M discharges

NASA Astrophysics Data System (ADS)

England, A. C.; Bell, R. E.; Hirshman, S. P.; Kaita, R.; Kugel, H. W.; LeBlanc, B. L.; Lee, D. K.; Okabayashi, M.; Sun, Y.-C.; Takahashi, H.

1997-09-01

The Princeton Beta Experiment-Modification (PBX-M) was run both with elliptical and with bean-shaped plasmas during the 1992 and 1993 operating periods. Two deuterium-fed neutral beams were used for auxiliary heating, and during 1992 the average power was 0741-3335/39/9/008/img13. This will be referred to as the lower neutral-beam power (LNBP) period. As many as four deuterium-fed neutral beams were used during 1993, and the average power was 0741-3335/39/9/008/img14. This will be referred to as the medium neutral-beam power (MNBP) period. The neutron source strength, Sn, showed a scaling with injected power 0741-3335/39/9/008/img15, 0741-3335/39/9/008/img16 for both the LMBP and MNBP periods. A much wider range of shaping parameters was studied during the MNBP as compared with the LNBP period. A weak positive dependence on bean shaping was observed for the LNBP, and a stronger positive dependence on shaping was observed for MNBP, viz 0741-3335/39/9/008/img17. High values of Sn were obtained in bean-shaped plasmas for the highest values of 0741-3335/39/9/008/img18 at 0741-3335/39/9/008/img19 for the LNBP. For the MNBP the highest values of Sn and stored energy were obtained at 0741-3335/39/9/008/img19, and the highest values of 0741-3335/39/9/008/img18 were obtained at 0741-3335/39/9/008/img22. The achievement of high Sn is aided by high neutral-beam power, high toroidal field, strong shaping, high electron temperature, and broad profiles. The achievement of high 0741-3335/39/9/008/img18 is aided by low toroidal field, high density, less shaping, broad profiles, and access to the H-mode, viz 0741-3335/39/9/008/img24. The achievement of high 0741-3335/39/9/008/img25 is aided by strong shaping, high density, broad profiles, and access to the H-mode, viz 0741-3335/39/9/008/img26. Some comparisons with the previous higher neutral-beam (HNBP) period in 1989 are also made.

A preliminary study on ice shape tracing with a laser light sheet

NASA Technical Reports Server (NTRS)

Mercer, Carolyn R.; Vargas, Mario; Oldenburg, John R.

1993-01-01

Preliminary work towards the development of an automated method of measuring the shape of ice forming on an airfoil during wind tunnel tests has been completed. A thin sheet of light illuminated the front surfaces of rime, glaze, and mixed ice shapes and a solid-state camera recorded images of each. A maximum intensity algorithm extracted the profiles of the ice shapes and the results were compared to hand tracings. Very good general agreement was found in each case.

OFT-1 reference flight profile. Deorbit through landing

NASA Technical Reports Server (NTRS)

Heath, D.; Gonzales, L.; Montez, M.; Hiott, J. M.; Ruda, R.; Kyle, H.

1977-01-01

Changes made in the de-orbiting through landing reference flight profile because of increases in Orbiter weight during entry and in the circular orbital attitude prior to deorbit are discussed. The rationale for the shaping of each phase is also presented.

Full-Physics Inverse Learning Machine for Satellite Remote Sensing of Ozone Profile Shapes and Tropospheric Columns

NASA Astrophysics Data System (ADS)

Xu, J.; Heue, K.-P.; Coldewey-Egbers, M.; Romahn, F.; Doicu, A.; Loyola, D.

2018-04-01

Characterizing vertical distributions of ozone from nadir-viewing satellite measurements is known to be challenging, particularly the ozone information in the troposphere. A novel retrieval algorithm called Full-Physics Inverse Learning Machine (FP-ILM), has been developed at DLR in order to estimate ozone profile shapes based on machine learning techniques. In contrast to traditional inversion methods, the FP-ILM algorithm formulates the profile shape retrieval as a classification problem. Its implementation comprises a training phase to derive an inverse function from synthetic measurements, and an operational phase in which the inverse function is applied to real measurements. This paper extends the ability of the FP-ILM retrieval to derive tropospheric ozone columns from GOME- 2 measurements. Results of total and tropical tropospheric ozone columns are compared with the ones using the official GOME Data Processing (GDP) product and the convective-cloud-differential (CCD) method, respectively. Furthermore, the FP-ILM framework will be used for the near-real-time processing of the new European Sentinel sensors with their unprecedented spectral and spatial resolution and corresponding large increases in the amount of data.

Advanced SLMs for microscopy

NASA Astrophysics Data System (ADS)

Linnenberger, A.

2018-02-01

Wavefront shaping devices such as deformable mirrors, liquid crystal spatial light modulators (SLMs), and active lenses are of considerable interest in microscopy for aberration correction, volumetric imaging, and programmable excitation. Liquid crystal SLMs are high resolution phase modulators capable of creating complex phase profiles to reshape, or redirect light within a three-dimensional (3D) volume. Recent advances in Meadowlark Optics (MLO) SLMs reduce losses by increasing fill factor from 83.4% to 96%, and improving resolution from 512 x 512 pixels to 1920 x 1152 pixels while maintaining a liquid crystal response time of 300 Hz at 1064 nm. This paper summarizes new SLM capabilities, and benefits for microscopy.

Application of Traditional and Nanostructure Materials for Medical Electron Beams Collimation: Numerical Simulation

NASA Astrophysics Data System (ADS)

Miloichikova, I. A.; Stuchebrov, S. G.; Zhaksybayeva, G. K.; Wagner, A. R.

2015-11-01

Nowadays, the commercial application of the electron accelerators grows in the industry, in the research investigations, in the medical diagnosis and treatment. In this regard, the electron beam profile modification in accordance with specific purposes is an actual task. In this paper the model of the TPU microtron extracted electron beam developed in the program “Computer Laboratory (PCLab)” is described. The internal beam divergence influence for the electron beam profile and depth dose distribution in the air is considered. The possibility of using the nanostructure materials for the electron beam formation was analyzed. The simulation data of the electron beam shape collimated by different materials (lead, corund- zirconia nanoceramic, gypsum) are shown. The collimator material influence for the electron beam profile and shape are analyzed.

Frequency-agile, rapid scanning cavity ring-down spectroscopy (FARS-CRDS) measurements of the (30012)←(00001) near-infrared carbon dioxide band

NASA Astrophysics Data System (ADS)

Long, D. A.; Wójtewicz, S.; Miller, C. E.; Hodges, J. T.

2015-08-01

We present new high accuracy measurements of the (30012)←(00001) CO2 band near 1575 nm recorded with a frequency-agile, rapid scanning cavity ring-down spectrometer. The resulting spectra were fit with the partially correlated, quadratic-speed-dependent Nelkin-Ghatak profile with line mixing. Significant differences were observed between the fitted line shape parameters and those found in existing databases, which are based upon more simplistic line profiles. Absolute transition frequencies, which were referenced to an optical frequency comb, are given, as well as the other line shape parameters needed to model this line profile. These high accuracy measurements should allow for improved atmospheric retrievals of greenhouse gas concentrations by current and future remote sensing missions.

Variation of velocity profile according to blood viscosity in a microfluidic channel

NASA Astrophysics Data System (ADS)

Yeom, Eunseop; Kang, Yang Jun; Lee, Sang-Joon

2014-11-01

The shear-thinning effect of blood flows is known to change blood viscosity. Since blood viscosity and motion of red blood cells (RBCs) are closely related, hemorheological variations have a strong influence on hemodynamic characteristics. Therefore, understanding on the relationship between the hemorheological and hemodynamic properties is importance for getting more detailed information on blood circulation in microvessels. In this study, the blood viscosity and velocity profiles in a microfluidic channel were systematically investigated. Rat blood was delivered in the microfluidic device which can measure blood viscosity by monitoring the flow-switching phenomenon. Velocity profiles of blood flows in the microchannel were measured by using a micro-particle image velocimetry (PIV) technique. Shape of velocity profiles measured at different flow rates was quantified by using a curve-fitting equation. It was observed that the shape of velocity profiles is highly correlated with blood viscosity. The study on the relation between blood viscosity and velocity profile would be helpful to understand the roles of hemorheological and hemodynamic properties in cardiovascular diseases. This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Korea Government (MSIP) (No. 2008-0061991).

Velocity Profile measurements in two-phase flow using multi-wave sensors

NASA Astrophysics Data System (ADS)

Biddinika, M. K.; Ito, D.; Takahashi, H.; Kikura, H.; Aritomi, M.

2009-02-01

Two-phase flow has been recognized as one of the most important phenomena in fluid dynamics. In addition, gas-liquid two-phase flow appears in various industrial fields such as chemical industries and power generations. In order to clarify the flow structure, some flow parameters have been measured by using many effective measurement techniques. The velocity profile as one of the important flow parameter, has been measured by using ultrasonic velocity profile (UVP) technique. This technique can measure velocity distributions along a measuring line, which is a beam formed by pulse ultrasounds. Furthermore, a multi-wave sensor can measure the velocity profiles of both gas and liquid phase using UVP method. In this study, two types of multi-wave sensors are used. A sensor has cylindrical shape, and another one has square shape. The piezoelectric elements of each sensor have basic frequencies of 8 MHz for liquid phase and 2 MHz for gas phase, separately. The velocity profiles of air-water bubbly flow in a vertical rectangular channel were measured by using these multi-wave sensors, and the validation of the measuring accuracy was performed by the comparison between the velocity profiles measured by two multi-wave sensors.

Adaptive management of ecosystem services across different land use regimes.

PubMed

Ruhl, J B

2016-12-01

Using adaptive management to manage desired flows of ecosystem services may seem on the surface to be a good fit, but many social, economic, environmental, legal, and political factors influence how good a fit. One strongly influential factor is the land use regime within which the profile of ecosystem services is being managed. Shaped largely by legal mandates, market forces, and social and cultural practices, different land use regimes present different opportunities for and constraints on goals for ecosystem services and pose different decision making environments. Even where all other conditions appear amenable to using adaptive management, therefore, it is essential to consider the constraining (or liberating) effects of different land use regimes when deciding whether to adopt adaptive management to achieve those goals and, if so, how to implement it. Copyright © 2016 Elsevier Ltd. All rights reserved.

Peak shapes of acids and bases under overloaded conditions in reversed-phase liquid chromatography, with weakly buffered mobile phases of various pH: A thermodynamic interpretation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gritti, Fabrice; Guiochon, Georges A

2009-01-01

We measured overloaded band profiles for a series of nine compounds (phenol, caffeine, 3-phenyl 1-propanol, 2-phenylbutyric acid, amphetamine, aniline, benzylamine, p-toluidine, and procainamidium chloride) on columns packed with four different C{sub 18}-bonded packing materials: XTerra-C{sub 18}, Gemini-C{sub 18}, Luna-C{sub 18}(2), and Halo-C{sub 18}, using buffered methanol-water mobile phases. The {sub W}{sup S}pH of the mobile phase was increased from 2.6 to 11.3. The buffer concentration (either phosphate, acetate, or carbonate buffers) was set constant at values below the maximum concentration of the sample in the band. The influence of the surface chemistry of the packing material on the retention andmore » the shape of the peaks was investigated. Adsorbents having a hybrid inorganic/organic structure tend to give peaks exhibiting moderate or little tailing. The retention and the shape of the band profiles can easily be interpreted at {sub W}{sup S}pHs that are well above or well below the {sub W}{sup S}pK{sub a} of the compound studied. In contrast, the peak shapes in the intermediary pH range (i.e., close to the compound {sub W}{sup S}pK{sub a}) have rarely been studied. These shapes reveal the complexity of the competitive adsorption behavior of couples of acido-basic conjugated compounds at {sub W}{sup S}pHs that are close to their {sub W}{sup S}pK{sub a}. They also reveal the role of the buffer capacity on the resulting peak shape. With increasing {sub W}{sup S}pH, the overloaded profiles are first langmuirian (isotherm type I) at low {sub W}{sup S}pHs, they become S-shaped (isotherm type II), then anti-langmuirian (isotherm type III), S-shaped again at intermediate {sub W}{sup S}pHs, and finally return to a langmuirian shape at high {sub W}{sup S}pHs. A new general adsorption isotherm model that takes into account the dissociation equilibrium of conjugated acidic and basic species in the bulk mobile phase accounts for these transient band shapes. An excellent agreement was achieved between experimental profiles and those calculated with a two-sites adsorption isotherm model at all {sub W}{sup S}pHs. The neutral species adsorbs strongly on a first type of sites that have a high density while the ionic species adsorb preferentially on a second type of sites that have a very low density. The evolution of the peak shape when the {sub W}{sup S}pH changes from acidic to basic is well explained by the weak buffer capacity of the mobile phase used compared to the concentration of the eluted compounds.« less

Cometary pick-up ions observed near Giacobini-Zinner

NASA Technical Reports Server (NTRS)

Gloeckler, G.; Hovestadt, D.; Ipavich, F. M.; Scholer, M.; Klecker, B.

1986-01-01

The number and energy density of cometary water-group ions observed near Comet Giacobini-Zinner are derived using the rest-frame distribution functions. The data reveal that density profiles of inbound and outbound passes and their shape correlate with pick-up ion production model predictions. The lose rate and production rate of water-group cometary molecules calculated from predicted and measured density profiles are 2 x 10 to the -6th/sec and 2.6 x 10 to the 28th/sec respectively. The shapes of the distribution functions are examined to study the solar wind/cometary ions interaction process.

Cometary pick-up ions observed near Giacobini-Zinner

NASA Astrophysics Data System (ADS)

Gloeckler, G.; Hovestadt, D.; Ipavich, F. M.; Scholer, M.; Klecker, B.; Galvin, A. B.

1986-03-01

The number and energy density of cometary water-group ions observed near Comet Giacobini-Zinner are derived using the rest-frame distribution functions. The data reveal that density profiles of inbound and outbound passes and their shape correlate with pick-up ion production model predictions. The lose rate and production rate of water-group cometary molecules calculated from predicted and measured density profiles are 2 x 10 to the -6th/sec and 2.6 x 10 to the 28th/sec respectively. The shapes of the distribution functions are examined to study the solar wind/cometary ions interaction process.

Improved ATIR concentrator photovoltaic module

NASA Astrophysics Data System (ADS)

Adriani, Paul M.; Mao, Erwang

2013-09-01

Novel aggregated total internal reflection (ATIR) concentrator photovoltaic module design comprises 2-D shaped primary and secondary optics that effectively combine optical efficiency, low profile, convenient range of acceptance angles, reliability, and manufacturability. This novel optical design builds upon previous investigations by improving the shapes of primary and secondary optics to enable improved long-term reliability and manufacturability. This low profile, low concentration (5x to 10x) design fits well with one-axis trackers that are often used for flat plate crystalline silicon photovoltaic modules in large scale ground mount installations. Standard mounting points, materials, and procedures apply without changes from flat plate modules.

Interfaces of Malignant and Immunologic Clonal Dynamics in Ovarian Cancer.

PubMed

Zhang, Allen W; McPherson, Andrew; Milne, Katy; Kroeger, David R; Hamilton, Phineas T; Miranda, Alex; Funnell, Tyler; Little, Nicole; de Souza, Camila P E; Laan, Sonya; LeDoux, Stacey; Cochrane, Dawn R; Lim, Jamie L P; Yang, Winnie; Roth, Andrew; Smith, Maia A; Ho, Julie; Tse, Kane; Zeng, Thomas; Shlafman, Inna; Mayo, Michael R; Moore, Richard; Failmezger, Henrik; Heindl, Andreas; Wang, Yi Kan; Bashashati, Ali; Grewal, Diljot S; Brown, Scott D; Lai, Daniel; Wan, Adrian N C; Nielsen, Cydney B; Huebner, Curtis; Tessier-Cloutier, Basile; Anglesio, Michael S; Bouchard-Côté, Alexandre; Yuan, Yinyin; Wasserman, Wyeth W; Gilks, C Blake; Karnezis, Anthony N; Aparicio, Samuel; McAlpine, Jessica N; Huntsman, David G; Holt, Robert A; Nelson, Brad H; Shah, Sohrab P

2018-05-07

High-grade serous ovarian cancer (HGSC) exhibits extensive malignant clonal diversity with widespread but non-random patterns of disease dissemination. We investigated whether local immune microenvironment factors shape tumor progression properties at the interface of tumor-infiltrating lymphocytes (TILs) and cancer cells. Through multi-region study of 212 samples from 38 patients with whole-genome sequencing, immunohistochemistry, histologic image analysis, gene expression profiling, and T and B cell receptor sequencing, we identified three immunologic subtypes across samples and extensive within-patient diversity. Epithelial CD8+ TILs negatively associated with malignant diversity, reflecting immunological pruning of tumor clones inferred by neoantigen depletion, HLA I loss of heterozygosity, and spatial tracking between T cell and tumor clones. In addition, combinatorial prognostic effects of mutational processes and immune properties were observed, illuminating how specific genomic aberration types associate with immune response and impact survival. We conclude that within-patient spatial immune microenvironment variation shapes intraperitoneal malignant spread, provoking new evolutionary perspectives on HGSC clonal dispersion. Copyright © 2018 Elsevier Inc. All rights reserved.

A fundamental mode Nd:GdVO4 laser pumped by a large aperture 808 nm VCSEL

NASA Astrophysics Data System (ADS)

Hao, Y. Q.; Ma, J. L.; Yan, C. L.; Liu, G. J.; Ma, X. H.; Gong, J. F.; Feng, Y.; Wei, Z. P.; Wang, Y. X.; Zhao, Y. J.

2013-05-01

A fundamental mode Nd:GdVO4 laser pumped by a vertical cavity surface emitting laser (VCSEL) is experimentally demonstrated. The VCSEL has a circular output-beam which makes it easier for it to be directly coupled to a Nd:GdVO4 microcrystal. In our research, a large aperture 808 nm VCSEL, with a multi-ring-shaped aperture (MRSA) and an almost Gaussian-shaped far-field profile, is used as the pumping source. Experimental results for the Nd:GdVO4 laser pumped by the VCSEL are presented. The maximum output peak power of 0.754 W is obtained under a pump peak power of 1.3 W, and the corresponding opto-optic conversion efficiency is 58.1%. The average slope efficiency is 65.8% from the threshold pump power of 0.2 W to the pump power of 1.3 W. The laser beam quality factors are measured to be {M}x2=1.2 0 and {M}y2=1.1 5.

Shape optimization of an autonomous underwater vehicle with a ducted propeller using computational fluid dynamics analysis

NASA Astrophysics Data System (ADS)

Joung, Tae-Hwan; Sammut, Karl; He, Fangpo; Lee, Seung-Keon

2012-03-01

Autonomous Underwater Vehicles (AUVs) provide a useful means of collecting detailed oceano-graphic information. The hull resistance of an AUV is an important factor in determining the power requirements and range of the vehicle. This paper describes a procedure using Computational Fluid Dynamics (CFD) for determining the hull resistance of an AUV under development, for a given propeller rotation speed and within a given range of AUV velocities. The CFD analysis results reveal the distribution of the hydrodynamic values (velocity, pressure, etc.) around the AUV hull and its ducted propeller. The paper then proceeds to present a methodology for optimizing the AUV profile in order to reduce the total resistance. This paper demonstrates that shape optimization of conceptual designs is possible using the commercial CFD package contained in Ansys™. The optimum design to minimize the drag force of the AUV was identified for a given object function and a set of constrained design parameters

Atomic Physics of Shocked Plasma in Winds of Massive Stars

NASA Technical Reports Server (NTRS)

Leutenegger, Maurice A.; Cohen, David H.; Owocki, Stanley P.

2012-01-01

High resolution diffraction grating spectra of X-ray emission from massive stars obtained with Chandra and XMM-Newton have revolutionized our understanding of their powerful, radiation-driven winds. Emission line shapes and line ratios provide diagnostics on a number of key wind parameters. Modeling of resolved emission line velocity profiles allows us to derive independent constraints on stellar mass-loss rates, leading to downward revisions of a factor of a few from previous measurements. Line ratios in He-like ions strongly constrain the spatial distribution of Xray emitting plasma, confirming the expectations of radiation hydrodynamic simulations that X-ray emission begins moderately close to the stellar surface and extends throughout the wind. Some outstanding questions remain, including the possibility of large optical depths in resonance lines, which is hinted at by differences in line shapes of resonance and intercombination lines from the same ion. Resonance scattering leads to nontrivial radiative transfer effects, and modeling it allows us to place constraints on shock size, density, and velocity structure

Wide-band profile domain pulsar timing analysis

NASA Astrophysics Data System (ADS)

Lentati, L.; Kerr, M.; Dai, S.; Hobson, M. P.; Shannon, R. M.; Hobbs, G.; Bailes, M.; Bhat, N. D. Ramesh; Burke-Spolaor, S.; Coles, W.; Dempsey, J.; Lasky, P. D.; Levin, Y.; Manchester, R. N.; Osłowski, S.; Ravi, V.; Reardon, D. J.; Rosado, P. A.; Spiewak, R.; van Straten, W.; Toomey, L.; Wang, J.; Wen, L.; You, X.; Zhu, X.

2017-04-01

We extend profile domain pulsar timing to incorporate wide-band effects such as frequency-dependent profile evolution and broad-band shape variation in the pulse profile. We also incorporate models for temporal variations in both pulse width and in the separation in phase of the main pulse and interpulse. We perform the analysis with both nested sampling and Hamiltonian Monte Carlo methods. In the latter case, we introduce a new parametrization of the posterior that is extremely efficient in the low signal-to-noise regime and can be readily applied to a wide range of scientific problems. We apply this methodology to a series of simulations, and to between seven and nine years of observations for PSRs J1713+0747, J1744-1134 and J1909-3744 with frequency coverage that spans 700-3600 Mhz. We use a smooth model for profile evolution across the full frequency range, and compare smooth and piecewise models for the temporal variations in dispersion measure (DM). We find that the profile domain framework consistently results in improved timing precision compared to the standard analysis paradigm by as much as 40 per cent for timing parameters. Incorporating smoothness in the DM variations into the model further improves timing precision by as much as 30 per cent. For PSR J1713+0747, we also detect pulse shape variation uncorrelated between epochs, which we attribute to variation intrinsic to the pulsar at a level consistent with previously published analyses. Not accounting for this shape variation biases the measured arrival times at the level of ˜30 ns, the same order of magnitude as the expected shift due to gravitational waves in the pulsar timing band.

A high resolution hand-held focused beam profiler

NASA Astrophysics Data System (ADS)

Zapata-Farfan, J.; Garduño-Mejía, J.; Rosete-Aguilar, M.; Ascanio, G.; Román-Moreno, C. J.

2017-05-01

The shape of a beam is important in any laser application and depending on the final implementation, there exists a preferred one which is defined by the irradiance distribution.1 The energy distribution (or laser beam profile) is an important parameter in a focused beam, for instance, in laser cut industry, where the beam shape determines the quality of the cut. In terms of alignment and focusing, the energy distribution also plays an important role since the system must be configured in order to reduce the aberration effects and achieve the highest intensity. Nowadays a beam profiler is used in both industry and research laboratories with the aim to characterize laser beams used in free-space communications, focusing and welding, among other systems. The purpose of the profile analyzers is to know the main parameters of the beam, to control its characteristics as uniformity, shape and beam size as a guide to align the focusing system. In this work is presented a high resolution hand-held and compact design of a beam profiler capable to measure at the focal plane, with covered range from 400 nm to 1000 nm. The detection is reached with a CMOS sensor sized in 3673.6 μm x 2738.4 μm which acquire a snap shot of the previously attenuated focused beam to avoid the sensor damage, the result is an image of beam intensity distribution, which is digitally processed with a RaspberryTMmodule gathering significant parameters such as beam waist, centroid, uniformity and also some aberrations. The profiler resolution is 1.4 μm and was probed and validated in three different focusing systems. The spot sizes measurements were compared with the Foucault knife-edge test.

Reversible wavefront shaping between Gaussian and Airy beams by mimicking gravitational field

NASA Astrophysics Data System (ADS)

Wang, Xiangyang; Liu, Hui; Sheng, Chong; Zhu, Shining

2018-02-01

In this paper, we experimentally demonstrate reversible wavefront shaping through mimicking gravitational field. A gradient-index micro-structured optical waveguide with special refractive index profile was constructed whose effective index satisfying a gravitational field profile. Inside the waveguide, an incident broad Gaussian beam is firstly transformed into an accelerating beam, and the generated accelerating beam is gradually changed back to a Gaussian beam afterwards. To validate our experiment, we performed full-wave continuum simulations that agree with the experimental results. Furthermore, a theoretical model was established to describe the evolution of the laser beam based on Landau’s method, showing that the accelerating beam behaves like the Airy beam in the small range in which the linear potential approaches zero. To our knowledge, such a reversible wavefront shaping technique has not been reported before.

Diode laser spectroscopy: precise spectral line shape measurements

NASA Astrophysics Data System (ADS)

Nadezhdinskii, A. I.

1996-07-01

When one speaks about modern trends in tunable diode laser spectroscopy (TDLS) one should mention that precise line shape measurements have become one of the most promising applications of diode lasers in high resolution molecular spectroscopy. Accuracy limitations of TDL spectrometers are considered in this paper, proving the ability to measure spectral line profile with precision better than 1%. A four parameter Voigt profile is used to fit the experimental spectrum, and the possibility of line shift measurements with an accuracy of 2 × 10 -5 cm -1 is shown. Test experiments demonstrate the error line intensity ratios to be less than 0.3% for the proposed approach. Differences between "soft" and "hard" models of line shape have been observed experimentally for the first time. Some observed resonance effects are considered with respect to collision adiabacity.

Optimal design of damping layers in SMA/GFRP laminated hybrid composites

NASA Astrophysics Data System (ADS)

Haghdoust, P.; Cinquemani, S.; Lo Conte, A.; Lecis, N.

2017-10-01

This work describes the optimization of the shape profiles for shape memory alloys (SMA) sheets in hybrid layered composite structures, i.e. slender beams or thinner plates, designed for the passive attenuation of flexural vibrations. The paper starts with the description of the material and architecture of the investigated hybrid layered composite. An analytical method, for evaluating the energy dissipation inside a vibrating cantilever beam is developed. The analytical solution is then followed by a shape profile optimization of the inserts, using a genetic algorithm to minimize the SMA material layer usage, while maintaining target level of structural damping. Delamination problem at SMA/glass fiber reinforced polymer interface is discussed. At the end, the proposed methodology has been applied to study the hybridization of a wind turbine layered structure blade with SMA material, in order to increase its passive damping.

Application specific beam profiles: new surface and thin-film refinement processes using beam shaping technologies

NASA Astrophysics Data System (ADS)

Hauschild, Dirk

2017-02-01

Today, the use of laser photons for materials processing is a key technology in nearly all industries. Most of the applications use circular beam shapes with Gaussian intensity distribution that is given by the resonator of the laser or by the power delivery via optical fibre. These beam shapes can be typically used for material removal with cutting or drilling and for selective removal of material layers with ablation processes. In addition to the removal of materials, it is possible to modify and improve the material properties in case the dose of laser photons and the resulting light-material interaction addresses a defined window of energy and dwell-time. These process windows have typically dwell-times between µs and s because of using sintering, melting, thermal diffusion or photon induced chemical and physical reaction mechanisms. Using beam shaping technologies the laser beam profiles can be adapted to the material properties and time-temperature and the space-temperature envelopes can be modified to enable selective annealing or crystallization of layers or surfaces. Especially the control of the process energy inside the beam and at its edges opens a large area of laser applications that can be addressed only with an optimized spatial and angular beam profile with down to sub-percent intensity variation used in e.g. immersion lithography tools with ArF laser sources. LIMO will present examples for new beam shapes and related material refinement processes even on large surfaces and give an overview about new mechanisms in laser material processing for current and coming industrial applications.

Efficient calculation of general Voigt profiles

NASA Astrophysics Data System (ADS)

Cope, D.; Khoury, R.; Lovett, R. J.

1988-02-01

An accurate and efficient program is presented for the computation of OIL profiles, generalizations of the Voigt profile resulting from the one-interacting-level model of Ward et al. (1974). These profiles have speed dependent shift and width functions and have asymmetric shapes. The program contains an adjustable error control parameter and includes the Voigt profile as a special case, although the general nature of this program renders it slower than a specialized Voigt profile method. Results on accuracy and computation time are presented for a broad set of test parameters, and a comparison is made with previous work on the asymptotic behavior of general Voigt profiles.

The RIASEC Profile of Foreign Language Teachers

ERIC Educational Resources Information Center

Swanson, Peter B.

2008-01-01

Vocational choice appears to crystallize during adolescence and one's career aspirations begin to take shape later. Over 40 years ago Holland studied incoming freshman to match vocational aspirations to vocational preference profiles. Individuals seeking to become foreign language teachers were assigned a Social, Artistic, Enterprising vocational…

Ion beams extraction and measurements of plasma parameters on a multi-frequencies microwaves large bore ECRIS with permanent magnets

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nozaki, Dai; Kiriyama, Ryutaro; Takenaka, Tomoya

2012-11-06

We have developed an all-permanent magnet large bore electron cyclotron resonance ion source (ECRIS) for broad ion beam processing. The cylindrically comb-shaped magnetic field configuration is adopted for efficient plasma production and good magnetic confinement. To compensate for disadvantages of fixed magnetic configuration, a traveling wave tube amplifier (TWTA) is used. In the comb-shaped ECRIS, it is difficult to achieve controlling ion beam profiles in the whole inside the chamber by using even single frequency-controllable TWTA (11-13GHz), because of large bore size with all-magnets. We have tried controlling profiles of plasma parameters and then those of extracted ion beams bymore » launching two largely different frequencies simultaneously, i.e., multi-frequencies microwaves. Here we report ion beam profiles and corresponding plasma parameters under various experimental conditions, dependence of ion beams against extraction voltages, and influence of different electrode positions on the electron density profile.« less

NMRDSP: an accurate prediction of protein shape strings from NMR chemical shifts and sequence data.

PubMed

Mao, Wusong; Cong, Peisheng; Wang, Zhiheng; Lu, Longjian; Zhu, Zhongliang; Li, Tonghua

2013-01-01

Shape string is structural sequence and is an extremely important structure representation of protein backbone conformations. Nuclear magnetic resonance chemical shifts give a strong correlation with the local protein structure, and are exploited to predict protein structures in conjunction with computational approaches. Here we demonstrate a novel approach, NMRDSP, which can accurately predict the protein shape string based on nuclear magnetic resonance chemical shifts and structural profiles obtained from sequence data. The NMRDSP uses six chemical shifts (HA, H, N, CA, CB and C) and eight elements of structure profiles as features, a non-redundant set (1,003 entries) as the training set, and a conditional random field as a classification algorithm. For an independent testing set (203 entries), we achieved an accuracy of 75.8% for S8 (the eight states accuracy) and 87.8% for S3 (the three states accuracy). This is higher than only using chemical shifts or sequence data, and confirms that the chemical shift and the structure profile are significant features for shape string prediction and their combination prominently improves the accuracy of the predictor. We have constructed the NMRDSP web server and believe it could be employed to provide a solid platform to predict other protein structures and functions. The NMRDSP web server is freely available at http://cal.tongji.edu.cn/NMRDSP/index.jsp.

Comparison between rotary and manual instrumentation in primary teeth.

PubMed

Crespo, S; Cortes, O; Garcia, C; Perez, L

2008-01-01

The aim of this study was to compare the efficiency in both, preparation time and root canal shape, when using the Nickel Titanium (Ni-Ti) rotary and K-Files hand instrumentation on root canal preparation of single rooted primary teeth. Sixty single rooted primary teeth were selected and divided into two equal groups: Group (I) 30 teeth instrumented with manual K-files and group (II) 30 teeth instrumented with Ni-Ti rotary files (ProFile 0.04). Instrumentation times were calculated and root canal impressions were taken with light bodied silicone in order to evaluate the shape. The data was analyzed with SPSS program using the t-test and the Chi-square test to compare their means. The preparation time with group (I) K-files was significantly higher than in group (II) rotary files (ProFile 0.04), with a p= .005. The ProFile system showed a significantly more favorable canal taper when compared to the K-files system (P= .002). The use of rotary files in primary teeth has several advantages when compared with manual K files: the efficiency in both, preparation time and root canal shape. 1. A decreased working time, that helps maintain patient cooperation by diminishing the potential for tiredness. 2. The shape of the root canal is more conical, favoring a higher quality of the root canal filling, and increasing clinical success.

Thermal deformation of cryogenically cooled silicon crystals under intense X-ray beams: measurement and finite-element predictions of the surface shape

PubMed Central

Zhang, Lin; Sánchez del Río, Manuel; Monaco, Giulio; Detlefs, Carsten; Roth, Thomas; Chumakov, Aleksandr I.; Glatzel, Pieter

2013-01-01

X-ray crystal monochromators exposed to white-beam X-rays in third-generation synchrotron light sources are subject to thermal deformations that must be minimized using an adequate cooling system. A new approach was used to measure the crystal shape profile and slope of several cryogenically cooled (liquid nitrogen) silicon monochromators as a function of beam power in situ and under heat load. The method utilizes multiple angular scans across the Bragg peak (rocking curve) at various vertical positions of a narrow-gap slit downstream from the monochromator. When increasing the beam power, the surface of the liquid-nitrogen-cooled silicon crystal deforms from a concave shape at low heat load to a convex shape at high heat load, passing through an approximately flat shape at intermediate heat load. Finite-element analysis is used to calculate the crystal thermal deformations. The simulated crystal profiles and slopes are in excellent agreement with experiments. The parameters used in simulations, such as material properties, absorbed power distribution on the crystal and cooling boundary conditions, are described in detail as they are fundamental for obtaining accurate results. PMID:23765298

Recovering Galaxy Rotation Speeds from Irregular Emission Profiles

NASA Astrophysics Data System (ADS)

Lavezzi, T. E.; Dickey, J. M.

1997-12-01

We simulate extragalactic emission spectra in order to determine whether the spectra of molecular gas measure the full velocity of disk rotation, despite their confined gas distributions. We present synthetic emission profiles to determine the effects on profile shapes due to factors such as telescope beam size. gas distribution, opacity, and pointing errors. We find that linewidths cease to be useful if the telescope beam resolves the solid body rotation region of the galaxy disk, or if the disk is very optically thick. Opacity is more problematic for edge-on galaxies; at lower optical depths, we find that very often a trough is created in the center of the emission line. We establish guidelines for rejecting spectra as unreliable disk-velocity indicators, and determine what corrections to the measured line widths at 20% and 50% of the peak intensity are best to recover twice the disk rotation velocity. Following the procedure of Bicay & Giovanelli (1986, AJ, 91, 705) we find that the 50% of peak intensity threshold for measuring linewidths (W50p, or FWHM) is the most robust, yielding the smallest measurement errors as a function of signal to noise, and requires the smallest turbulence corrections.

Object Recognition in Flight: How Do Bees Distinguish between 3D Shapes?

PubMed Central

Werner, Annette; Stürzl, Wolfgang; Zanker, Johannes

2016-01-01

Honeybees (Apis mellifera) discriminate multiple object features such as colour, pattern and 2D shape, but it remains unknown whether and how bees recover three-dimensional shape. Here we show that bees can recognize objects by their three-dimensional form, whereby they employ an active strategy to uncover the depth profiles. We trained individual, free flying honeybees to collect sugar water from small three-dimensional objects made of styrofoam (sphere, cylinder, cuboids) or folded paper (convex, concave, planar) and found that bees can easily discriminate between these stimuli. We also tested possible strategies employed by the bees to uncover the depth profiles. For the card stimuli, we excluded overall shape and pictorial features (shading, texture gradients) as cues for discrimination. Lacking sufficient stereo vision, bees are known to use speed gradients in optic flow to detect edges; could the bees apply this strategy also to recover the fine details of a surface depth profile? Analysing the bees’ flight tracks in front of the stimuli revealed specific combinations of flight maneuvers (lateral translations in combination with yaw rotations), which are particularly suitable to extract depth cues from motion parallax. We modelled the generated optic flow and found characteristic patterns of angular displacement corresponding to the depth profiles of our stimuli: optic flow patterns from pure translations successfully recovered depth relations from the magnitude of angular displacements, additional rotation provided robust depth information based on the direction of the displacements; thus, the bees flight maneuvers may reflect an optimized visuo-motor strategy to extract depth structure from motion signals. The robustness and simplicity of this strategy offers an efficient solution for 3D-object-recognition without stereo vision, and could be employed by other flying insects, or mobile robots. PMID:26886006

Object Recognition in Flight: How Do Bees Distinguish between 3D Shapes?

PubMed

Werner, Annette; Stürzl, Wolfgang; Zanker, Johannes

2016-01-01

Honeybees (Apis mellifera) discriminate multiple object features such as colour, pattern and 2D shape, but it remains unknown whether and how bees recover three-dimensional shape. Here we show that bees can recognize objects by their three-dimensional form, whereby they employ an active strategy to uncover the depth profiles. We trained individual, free flying honeybees to collect sugar water from small three-dimensional objects made of styrofoam (sphere, cylinder, cuboids) or folded paper (convex, concave, planar) and found that bees can easily discriminate between these stimuli. We also tested possible strategies employed by the bees to uncover the depth profiles. For the card stimuli, we excluded overall shape and pictorial features (shading, texture gradients) as cues for discrimination. Lacking sufficient stereo vision, bees are known to use speed gradients in optic flow to detect edges; could the bees apply this strategy also to recover the fine details of a surface depth profile? Analysing the bees' flight tracks in front of the stimuli revealed specific combinations of flight maneuvers (lateral translations in combination with yaw rotations), which are particularly suitable to extract depth cues from motion parallax. We modelled the generated optic flow and found characteristic patterns of angular displacement corresponding to the depth profiles of our stimuli: optic flow patterns from pure translations successfully recovered depth relations from the magnitude of angular displacements, additional rotation provided robust depth information based on the direction of the displacements; thus, the bees flight maneuvers may reflect an optimized visuo-motor strategy to extract depth structure from motion signals. The robustness and simplicity of this strategy offers an efficient solution for 3D-object-recognition without stereo vision, and could be employed by other flying insects, or mobile robots.

The role of deep-water sedimentary processes in shaping a continental margin: The Northwest Atlantic

USGS Publications Warehouse

Mosher, David C.; Campbell, D.C.; Gardner, J.V.; Piper, D.J.W.; Chaytor, Jason; Rebesco, M.

2017-01-01

The tectonic history of a margin dictates its general shape; however, its geomorphology is generally transformed by deep-sea sedimentary processes. The objective of this study is to show the influences of turbidity currents, contour currents and sediment mass failures on the geomorphology of the deep-water northwestern Atlantic margin (NWAM) between Blake Ridge and Hudson Trough, spanning about 32° of latitude and the shelf edge to the abyssal plain. This assessment is based on new multibeam echosounder data, global bathymetric models and sub-surface geophysical information.The deep-water NWAM is divided into four broad geomorphologic classifications based on their bathymetric shape: graded, above-grade, stepped and out-of-grade. These shapes were created as a function of the balance between sediment accumulation and removal that in turn were related to sedimentary processes and slope-accommodation. This descriptive method of classifying continental margins, while being non-interpretative, is more informative than the conventional continental shelf, slope and rise classification, and better facilitates interpretation concerning dominant sedimentary processes.Areas of the margin dominated by turbidity currents and slope by-pass developed graded slopes. If sediments did not by-pass the slope due to accommodation then an above grade or stepped slope resulted. Geostrophic currents created sedimentary bodies of a variety of forms and positions along the NWAM. Detached drifts form linear, above-grade slopes along their crests from the shelf edge to the deep basin. Plastered drifts formed stepped slope profiles. Sediment mass failure has had a variety of consequences on the margin morphology; large mass-failures created out-of-grade profiles, whereas smaller mass failures tended to remain on the slope and formed above-grade profiles at trough-mouth fans, or nearly graded profiles, such as offshore Cape Fear.

A Parametric Approach to Shape Field-Relevant Blast Wave Profiles in Compressed-Gas-Driven Shock Tube

PubMed Central

Sundaramurthy, Aravind; Chandra, Namas

2014-01-01

Detonation of a high-explosive produces shock-blast wave, shrapnel, and gaseous products. While direct exposure to blast is a concern near the epicenter, shock-blast can affect subjects, even at farther distances. When a pure shock-blast wave encounters the subject, in the absence of shrapnels, fall, or gaseous products the loading is termed as primary blast loading and is the subject of this paper. The wave profile is characterized by blast overpressure, positive time duration, and impulse and called herein as shock-blast wave parameters (SWPs). These parameters in turn are uniquely determined by the strength of high explosive and the distance of the human subjects from the epicenter. The shape and magnitude of the profile determine the severity of injury to the subjects. As shown in some of our recent works (1–3), the profile not only determines the survival of the subjects (e.g., animals) but also the acute and chronic biomechanical injuries along with the following bio-chemical sequelae. It is extremely important to carefully design and operate the shock tube to produce field-relevant SWPs. Furthermore, it is vital to identify and eliminate the artifacts that are inadvertently introduced in the shock-blast profile that may affect the results. In this work, we examine the relationship between shock tube adjustable parameters (SAPs) and SWPs that can be used to control the blast profile; the results can be easily applied to many of the laboratory shock tubes. Further, replication of shock profile (magnitude and shape) can be related to field explosions and can be a standard in comparing results across different laboratories. Forty experiments are carried out by judiciously varying SAPs such as membrane thickness, breech length (66.68–1209.68 mm), measurement location, and type of driver gas (nitrogen, helium). The effects SAPs have on the resulting shock-blast profiles are shown. Also, the shock-blast profiles of a TNT explosion from ConWep software is compared with the profiles obtained from the shock tube. To conclude, our experimental results demonstrate that a compressed-gas shock tube when designed and operated carefully can replicate the blast time profiles of field explosions accurately. Such a faithful replication is an essential first step when studying the effects of blast induced neurotrauma using animal models. PMID:25520701

A simplified 137Cs transport model for estimating erosion rates in undisturbed soil.

PubMed

Zhang, Xinbao; Long, Yi; He, Xiubin; Fu, Jiexiong; Zhang, Yunqi

2008-08-01

(137)Cs is an artificial radionuclide with a half-life of 30.12 years which released into the environment as a result of atmospheric testing of thermo-nuclear weapons primarily during the period of 1950s-1970s with the maximum rate of (137)Cs fallout from atmosphere in 1963. (137)Cs fallout is strongly and rapidly adsorbed by fine particles in the surface horizons of the soil, when it falls down on the ground mostly with precipitation. Its subsequent redistribution is associated with movements of the soil or sediment particles. The (137)Cs nuclide tracing technique has been used for assessment of soil losses for both undisturbed and cultivated soils. For undisturbed soils, a simple profile-shape model was developed in 1990 to describe the (137)Cs depth distribution in profile, where the maximum (137)Cs occurs in the surface horizon and it exponentially decreases with depth. The model implied that the total (137)Cs fallout amount deposited on the earth surface in 1963 and the (137)Cs profile shape has not changed with time. The model has been widely used for assessment of soil losses on undisturbed land. However, temporal variations of (137)Cs depth distribution in undisturbed soils after its deposition on the ground due to downward transport processes are not considered in the previous simple profile-shape model. Thus, the soil losses are overestimated by the model. On the base of the erosion assessment model developed by Walling, D.E., He, Q. [1999. Improved models for estimating soil erosion rates from cesium-137 measurements. Journal of Environmental Quality 28, 611-622], we discuss the (137)Cs transport process in the eroded soil profile and make some simplification to the model, develop a method to estimate the soil erosion rate more expediently. To compare the soil erosion rates calculated by the simple profile-shape model and the simple transport model, the soil losses related to different (137)Cs loss proportions of the reference inventory at the Kaixian site of the Three Gorge Region, China are estimated by the two models. The over-estimation of the soil loss by using the previous simple profile-shape model obviously increases with the time period from the sampling year to the year of 1963 and (137)Cs loss proportion of the reference inventory. As to 20-80% of (137)Cs loss proportions of the reference inventory at the Kaixian site in 2004, the annual soil loss depths estimated by the new simplified transport process model are only 57.90-56.24% of the values estimated by the previous model.

The variation of rotation curve shapes as a signature of the effects of baryons on dark matter density profiles

NASA Astrophysics Data System (ADS)

Brook, Chris B.

2015-12-01

Rotation curves of galaxies show a wide range of shapes, which can be paramaterized as scatter in Vrot(1 kpc)/Vmax , i.e. the ratio of the rotation velocity measured at 1 kpc and the maximum measured rotation velocity. We examine whether the observed scatter can be accounted for by combining scatters in disc scalelengths, the concentration-halo mass relation, and the M⋆-Mhalo relation. We use these scatters to create model galaxy populations; when housed within dark matter haloes that have universal, Navarro, Frenk & White density profiles, the model does not match the lowest observed values of Vrot(1 kpc)/Vmax and has too little scatter in Vrot(1 kpc)/Vmax compared to observations. By contrast, a model using a mass-dependent dark matter profile, where the inner slope is determined by the ratio of M⋆/Mhalo, produces galaxies with low values of Vrot(1 kpc)/Vmax and a much larger scatter, both in agreement with observation. We conclude that the large observed scatter in Vrot(1 kpc)/Vmax favours density profiles that are significantly affected by baryonic processes. Alternative dark matter core formation models such as self-interacting dark matter may also account for the observed variation in rotation curve shapes, but these observations may provide important constraints in terms of core sizes, and whether they vary with halo mass and/or merger history.

The relevance of light diffusion profiles for interstitial PDT using light-diffusing optical fibers

NASA Astrophysics Data System (ADS)

Stringasci, Mirian D.; Fortunato, Thereza C.; Moriyama, Lilian T.; Vollet Filho, José Dirceu; Bagnato, Vanderlei S.; Kurachi, Cristina

2017-02-01

Photodynamic therapy (PDT) is a technique used for several tumor types treatment. Light penetration on biological tissue is one limiting factor for PDT applied to large tumors. An alternative is using interstitial PDT, in which optical fibers are inserted into tumors. Cylindrical diffusers have been used in interstitial PDT. Light emission of different diffusers depends on the manufacturing process, size and optical properties of fibers, which make difficult to establish an adequate light dosimetry, since usually light profile is not designed for direct tissue-fiber contact. This study discusses the relevance of light distribution by a cylindrical diffuser into a turbid lipid emulsion solution, and how parts of a single diffuser contribute to illumination. A 2 cm-long cylindrical diffuser optical fiber was connected to a diode laser (630 nm), and the light spatial distribution was measured by scanning the solution with a collection probe. From the light field profile generated by a 1 mm-long intermediary element of a 20 mm-long cylindrical diffuser, recovery of light distribution for the entire diffuser was obtained. PDT was performed in rat healthy liver for a real treatment outcome analysis. By using computational tools, a typical necrosis profile generated by the irradiation with such a diffuser fiber was reconstructed. The results showed that it was possible predicting theoretically the shape of a necrosis profile in a healthy, homogeneous tissue with reasonable accuracy. The ability to predict the necrosis profile obtained from an interstitial illumination by optical diffusers has the potential improve light dosimetry for interstitial PDT.

A real-time beam-profile monitor for a PET cyclotron

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hoehr, C.; Uittenbosch, T.; Verzilov, V.

2012-12-19

Beam profiles in medical cyclotrons are traditionally measured using techniques that do not provide any information about short-term fluctuations of the beam shape or beam intensity. To overcome this, we have developed a real-time harp beam profile monitor which can withstand beam power in excess of 300 W. The monitor and electronics were constructed and applied toward a 13 MeV proton beam with current of up to 25 {mu}A. Herein are reported preliminary beam-profile measurement results.

A real-time beam-profile monitor for a PET cyclotron

NASA Astrophysics Data System (ADS)

Hoehr, C.; Uittenbosch, T.; Verzilov, V.; English, W.; Buckley, K.; Gray, D.; Kellog, S.; Cameron, D.; Schaffer, P.

2012-12-01

Beam profiles in medical cyclotrons are traditionally measured using techniques that do not provide any information about short-term fluctuations of the beam shape or beam intensity. To overcome this, we have developed a real-time harp beam profile monitor which can withstand beam power in excess of 300 W. The monitor and electronics were constructed and applied toward a 13 MeV proton beam with current of up to 25 μA. Herein are reported preliminary beam-profile measurement results.

France: Factors Shaping Foreign Policy, and Issues in U.S.-French Relations

DTIC Science & Technology

2009-05-20

TYPE 3. DATES COVERED 00-00-2009 to 00-00-2009 4. TITLE AND SUBTITLE France : Factors Shaping Foreign Policy, and Issues in U.S.- French ...Z39-18 France : Factors Shaping Foreign Policy, and Issues in U.S.- French Relations Congressional Research Service Summary The factors that shape... French foreign policy have changed since the end of the Cold War. The perspectives of France and the United States have diverged in some cases. More

Dynamic profile of health investment and the evolution of elderly health.

PubMed

Lo, Te-Fen; Hsieh, Chee-Ruey

2013-01-01

A considerable number of studies have sought to examine the determinants of elderly health. Nevertheless, few of them incorporate a life-course perspective to analyze the dynamics of transition for both health conditions and their predictors. We utilize a nationally representative longitudinal data set of 4007 Taiwanese aged 60 or over and employ discrete-time duration models to investigate the association between annual mortality and its potential risk factors over a nearly twenty-year period (1989-2007). We place particular emphasis on the inherently dynamic character of Grossman's model, and specifically on how public and private health investment shape the personal health outcome over time. Our results support the hypothesis that depreciation rates depend on personal characteristics. In addition, we find that the dynamic profiles of both public and private health investment significantly influence the elderly mortality. An important implication of our study is that implementing universal health insurance and tobacco control programs are effective channels through which the government improves personal health. Copyright © 2012 Elsevier Ltd. All rights reserved.

Spatially scanned two-color mid-infrared interferometer for FTU

NASA Astrophysics Data System (ADS)

Canton, A.; Innocente, P.; Martini, S.; Tasinato, L.; Tudisco, O.

2001-01-01

The design of a scanning beam two-color mid-infrared (MIR) interferometer is presented. The diagnostic is being developed for the Frascati Tokamak Upgrade (FTU) which calls for a new interferometer to perform detailed study of advanced confinement regimes in D-shaped plasmas. After performing a feasibility study and a prototype test, we designed a scanning interferometer based on a resonant tilting mirror providing 40 chords of ≈1 cm diameter and a full profile every 62 μs. Such a high number of chords is obtained with a very simple optical scheme, resulting in a system which is compact, low cost, and easy to align. An important feature of the interferometer is its higher immunity to fringe jumps compared to conventional far infrared (FIR) systems. Three main factors contribute to that: the high critical density associated to MIR beams, the large bandwidth provided by 40 MHz heterodyne detection, and the fact that each scan provides a "self-consistent" profile.

Evidence for a Sudden Magnetic Field Reconfiguration in Soft Gamma Repeater 1900+14

NASA Technical Reports Server (NTRS)

Woods, Peter M.; Kouveliotou, Chryssa; Gogus, Ersin; Finger, Mark H.; Swank, Jean; Smith, Don A.; Hurley, Kevin; Thompson, Christopher

2001-01-01

We report the detection of large flux changes in the persistent X-ray flux of soft gamma repeater (SGR) 1900 + 14 during its burst active episode in 1998. Most notably, we find a factor of approx. 700 increase in the nonburst X-ray flux following the August 27 flare, which decayed in time as a power law. Our measurements indicate that the pulse fraction remains constant throughout this decay. This suggests a global flux enhancement as a consequence of the August 27 flare rather than localized heating. While the persistent flux has since recovered to the preoutburst level, the pulse profile has not. The pulse shape changed to a near sinusoidal profile within the tail of the August 27 flare (in gamma-rays), and this effect has persisted for more than 1.5 years (in X-rays). The results presented here suggest that the magnetic field of the neutron star in SGR 1900 + 14 was significantly altered (perhaps globally) during the giant flare of August 27.

Trenonacog alfa for prophylaxis, on-demand and perioperative management of hemophilia B.

PubMed

Brennan, Yvonne; Curnow, Jennifer; Favaloro, Emmanuel J

2018-01-01

Current treatment for hemophilia B involves replacing the missing coagulation factor IX (FIX) with either plasma-derived or recombinant (r) FIX. Trenonacog alfa is the third normal half-life rFIX that has been granted FDA approval. Area covered: In this review, the authors examine trenonacog alfa for the treatment of hemophilia B including prophylaxis, on-demand and perioperative hemostasis. They compare the PK profile to nonacog alfa and evaluate the drug's efficacy and safety from published studies. Expert opinion: Trenonacog alfa appears to be an effective and safe treatment option for patients with hemophilia B with a PK profile similar to that of nonacog alfa. Despite the advent of extended half-life rFIX and other novel therapeutic approaches, normal half-life rFIX products, including trenonacog alfa, are likely to continue to have a place in hemophilia B treatment for at least the immediate future while the new landscape takes shape, particularly in countries that cannot afford the newer treatments.

The effect of the amino-acid side chains on the energy profiles for ion transport in the gramicidin A channel.

PubMed

Etchebest, C; Pullman, A

1985-02-01

Computations on the energy profiles for Na+ in the gramicidin A (GA) channel have been extended by introducing the effect, previously neglected, of the amino acid side chains of GA, fixed in their most stable conformations. The calculations have been performed in two approximations: 1) with the ethanolamine tail fixed in its most stable conformation, 2) with the tail allowed to optimize its conformation upon the progression of the ion. In both approximations the overall shape of the energy profile is very similar to that obtained in the absence of the side chains. One observes, however, a general lowering of the profile upon the adjunction of the side chains. The analysis of the factors responsible for this energy lowering indicates that it is due essentially to the electrostatic and polarisation components of the interaction which interplay differently, however, in the different parts of the channel. A particular role is attributed in this respect to the tryptophan residues of GA. The role of the 4 tryptophans present, Trp 15, 13, 11 and 9, is individualized by stripping of one of them at a time. The strongest effect on the energy deepening is due to Trp 13 and is particularly prominent in the entrance zone at 14.5A from the center of the channel. The result indicates the possibility of investigating theoretically the effect on the energy profiles of the substitution of the "natural" side chain by others.

Silicone gel breast implants: science and testing.

PubMed

Kinney, Brian M; Jeffers, Lynn L C; Ratliff, Gregory E; Carlisle, Dan A

2014-07-01

Since the first generation of breast implants, major design innovations, including consistency of the gel, palpability and thickness of the shell, and barrier materials in the shell, have been introduced. Surgeons have not had metrics to assess and compare available implants. Research at independent laboratories included 4 tests: gel elasticity (the gel's ability to retain its shape), gel compression fracture (the resistance to permanent gel deformation), gel-shell peel (the integration of the gel with shell as a cohesive unit), and morphological analysis. Sientra's round High-Strength Cohesive (HSC) experienced the least gel elasticity (5.805 mm), whereas Allergan's round implants experienced the most (7.465 mm). Among shaped implants, Allergan 410 experienced the least gel elasticity (3.242 mm), whereas the Sientra HSC+ implant experienced the most (4.270 mm). Sientra's round (36.32 lbf) and shaped (44.16 lbf) implants demonstrated the highest resistance to gel fracture, with Allergan's implants demonstrating the least among round (23.06 lbf) implants and Mentor Contour Profile Gel (CPG) among shaped (30.45 lbf) implants. For the gel-shell peel test, Sientra's implant required over 26% greater force than Allergan's implant and over 35% greater force than Mentor's implant. Sientra's shaped implants required more than double the peel force than Allergan 410 (119% greater) and Mentor CPG (130% greater). Morphological results showed Sientra's implants preserved structural integrity (-1.10% change). The initial findings show that these implant characteristics are individual factors to be considered separately and are not necessarily correlative. Further study of implants using these and other testing techniques will help clinicians choose between implants.

Comparison of GOME tropospheric NO2 columns with NO2 profiles deduced from ground-based in situ measurements

NASA Astrophysics Data System (ADS)

Schaub, D.; Boersma, K. F.; Kaiser, J. W.; Weiss, A. K.; Folini, D.; Eskes, H. J.; Buchmann, B.

2006-08-01

Nitrogen dioxide (NO2) vertical tropospheric column densities (VTCs) retrieved from the Global Ozone Monitoring Experiment (GOME) are compared to coincident ground-based tropospheric NO2 columns. The ground-based columns are deduced from in situ measurements at different altitudes in the Alps for 1997 to June 2003, yielding a unique long-term comparison of GOME NO2 VTC data retrieved by a collaboration of KNMI (Royal Netherlands Meteorological Institute) and BIRA/IASB (Belgian Institute for Space Aeronomy) with independently derived tropospheric NO2 profiles. A first comparison relates the GOME retrieved tropospheric columns to the tropospheric columns obtained by integrating the ground-based NO2 measurements. For a second comparison, the tropospheric profiles constructed from the ground-based measurements are first multiplied with the averaging kernel (AK) of the GOME retrieval. The second approach makes the comparison independent from the a priori NO2 profile used in the GOME retrieval. This allows splitting the total difference between the column data sets into two contributions: one that is due to differences between the a priori and the ground-based NO2 profile shapes, and another that can be attributed to uncertainties in both the remaining retrieval parameters (such as, e.g., surface albedo or aerosol concentration) and the ground-based in situ NO2 profiles. For anticyclonic clear sky conditions the comparison indicates a good agreement between the columns (n=157, R=0.70/0.74 for the first/second comparison approach, respectively). The mean relative difference (with respect to the ground-based columns) is -7% with a standard deviation of 40% and GOME on average slightly underestimating the ground-based columns. Both data sets show a similar seasonal behaviour with a distinct maximum of spring NO2 VTCs. Further analysis indicates small GOME columns being systematically smaller than the ground-based ones. The influence of different shapes in the a priori and the ground-based NO2 profile is analysed by considering AK information. It is moderate and indicates similar shapes of the profiles for clear sky conditions. Only for large GOME columns, differences between the profile shapes explain the larger part of the relative difference. In contrast, the other error sources give rise to the larger relative differences found towards smaller columns. Further, for the clear sky cases, errors from different sources are found to compensate each other partially. The comparison for cloudy cases indicates a poorer agreement between the columns (n=60, R=0.61). The mean relative difference between the columns is 60% with a standard deviation of 118% and GOME on average overestimating the ground-based columns. The clear improvement after inclusion of AK information (n=60, R=0.87) suggests larger errors in the a priori NO2 profiles under cloudy conditions and demonstrates the importance of using accurate profile information for (partially) clouded scenes.

Soil water dynamics during precipitation in genetic horizons of Retisol

NASA Astrophysics Data System (ADS)

Zaleski, Tomasz; Klimek, Mariusz; Kajdas, Bartłomiej

2017-04-01

Retisols derived from silty deposits dominate in the soil cover of the Carpathian Foothills. The hydrophysical properties of these are determined by the grain-size distribution of the parent material and the soil's "primary" properties shaped in the deposition process. The other contributing factors are the soil-forming processes, such as lessivage (leaching of clay particles), and the morphogenetic processes that presently shape the relief. These factors are responsible for the "secondary" differentiation of hydrophysical properties across the soil profile. Both the primary and secondary hydrophysical properties of soils (the rates of water retention, filtration and infiltration, and the moisture distribution over the soil profile) determine their ability to take in rainfall, the amount of rainwater taken in, and the ways of its redistribution. The aims of the study, carried out during 2015, were to investigate the dynamics of soil moisture in genetic horizons of Retisol derived from silty deposits and to recognize how fast and how deep water from precipitation gets into soil horizons. Data of soil moisture were measured using 5TM moisture and temperature sensor and collected by logger Em50 (Decagon Devices USA). Data were captured every 10 minutes from 6 sensors at depths: - 10 cm, 20 cm, 40 cm, 60 cm and 80 cm. Precipitation data come from meteorological station situated 50 m away from the soil profile. Two zones differing in the type of water regime were distinguished in Retisol: an upper zone comprising humic and eluvial horizons, and a lower zone consisting of illuvial and parent material horizons. The upper zone shows smaller retention of water available for plants, and relatively wide fluctuations in moisture content, compared to the lower zone. The lower zone has stable moisture content during the vegetation season, with values around the water field capacity. Large changes in soil moisture were observed while rainfall. These changes depend on the volume of the precipitation and soil moisture before the precipitation. The following changes of moisture in the soil profile during precipitation were distinguished: if soil moisture in upper zone horizons oscillates around field capacity (higher than 0.30 m3ṡm-3) there is an evident increase in soil moisture also in the lower zone horizons. If soil moisture in the upper zone horizons is much lower than the field capacity (less than 0.20 m3ṡm-3), the soil moisture in the lower zone has very little fluctuations. The range of wetting front in the soil profile depends on the volume of the precipitation and soil moisture. The heavier precipitation, the wetting front in soil profile reaches deeper horizons. The wetter the soil is, the faster soil moisture in the deeper genetic horizons increase. This Research was financed by the Ministry of Science and Higher Education of the Republic of Poland, DS No. 3138/KGiOG/2016.

Spatially modulated laser pulses for printing electronics.

PubMed

Auyeung, Raymond C Y; Kim, Heungsoo; Mathews, Scott; Piqué, Alberto

2015-11-01

The use of a digital micromirror device (DMD) in laser-induced forward transfer (LIFT) is reviewed. Combining this technique with high-viscosity donor ink (silver nanopaste) results in laser-printed features that are highly congruent in shape and size to the incident laser beam spatial profile. The DMD empowers LIFT to become a highly parallel, rapidly reconfigurable direct-write technology. By adapting half-toning techniques to the DMD bitmap image, the laser transfer threshold fluence for 10 μm features can be reduced using an edge-enhanced beam profile. The integration of LIFT with this beam-shaping technique allows the printing of complex large-area patterns with a single laser pulse.

Shape and Composition Map of a Prepyramid Quantum Dot

NASA Astrophysics Data System (ADS)

Spencer, Brian

2006-03-01

We present a theory for the shape, size, and nonuniform composition profile of a small prepyramid island in an alloy epitaxial film when surface diffusion is much faster than deposition and bulk diffusion. The predicted composition profile has segregation of the larger misfit component to the island peak, with segregation enhanced by misfit strain and solute strain but retarded by alloy solution thermodynamics. Vertical composition gradients through the center of the island due to this mechanism are on the order of 2%/nm for GeXSi1-X/Si and 10 - 15%/nm for InXGaAs1-X/GaAs [PRL 95, 206101 (2005)].

The ratio of profile peak separations as a probe of pulsar radio-beam structure

NASA Astrophysics Data System (ADS)

Dyks, J.; Pierbattista, M.

2015-12-01

The known population of pulsars contains objects with four- and five-component profiles, for which the peak-to-peak separations between the inner and outer components can be measured. These Q- and M-type profiles can be interpreted as a result of sightline cut through a nested-cone beam, or through a set of azimuthal fan beams. We show that the ratio RW of the components' separations provides a useful measure of the beam shape, which is mostly independent of parameters that determine the beam scale and complicate interpretation of simpler profiles. In particular, the method does not depend on the emission altitude and the dipole tilt distribution. The different structures of the radio beam imply manifestly different statistical distributions of RW, with the conal model being several orders of magnitude less consistent with data than the fan-beam model. To bring the conal model into consistency with data, strong effects of observational selection need to be called for, with 80 per cent of Q and M profiles assumed to be undetected because of intrinsic blending effects. It is concluded that the statistical properties of Q and M profiles are more consistent with the fan-shaped beams, than with the traditional nested-cone geometry.

The impact of baryonic discs on the shapes and profiles of self-interacting dark matter halos

NASA Astrophysics Data System (ADS)

Sameie, Omid; Creasey, Peter; Yu, Hai-Bo; Sales, Laura V.; Vogelsberger, Mark; Zavala, Jesús

2018-06-01

We employ isolated N-body simulations to study the response of self-interacting dark matter (SIDM) halos in the presence of the baryonic potentials. Dark matter self-interactions lead to kinematic thermalization in the inner halo, resulting in a tight correlation between the dark matter and baryon distributions. A deep baryonic potential shortens the phase of SIDM core expansion and triggers core contraction. This effect can be further enhanced by a large self-scattering cross section. We find the final SIDM density profile is sensitive to the baryonic concentration and the strength of dark matter self-interactions. Assuming a spherical initial halo, we also study evolution of the SIDM halo shape together with the density profile. The halo shape at later epochs deviates from spherical symmetry due to the influence of the non-spherical disc potential, and its significance depends on the baryonic contribution to the total gravitational potential, relative to the dark matter one. In addition, we construct a multi-component model for the Milky Way, including an SIDM halo, a stellar disc and a bulge, and show it is consistent with observations from stellar kinematics and streams.

Patterns and Prevalence of Core Profile Types in the WPPSI Standardization Sample.

ERIC Educational Resources Information Center

Glutting, Joseph J.; McDermott, Paul A.

1990-01-01

Found most representative subtest profiles for 1,200 children comprising standardization sample of Wechsler Preschool and Primary Scale of Intelligence (WPPSI). Grouped scaled scores from WPPSI subtests according to similar level and shape using sequential minimum-variance cluster analysis with independent replications. Obtained final solution of…

Broadband, high-resolution investigation of advanced absorption line shapes at high temperature

NASA Astrophysics Data System (ADS)

Schroeder, Paul J.; Cich, Matthew J.; Yang, Jinyu; Swann, William C.; Coddington, Ian; Newbury, Nathan R.; Drouin, Brian J.; Rieker, Gregory B.

2017-08-01

Spectroscopic studies of planetary atmospheres and high-temperature processes (e.g., combustion) require absorption line-shape models that are accurate over extended temperature ranges. To date, advanced line shapes, like the speed-dependent Voigt and Rautian profiles, have not been tested above room temperature with broadband spectrometers. We investigate pure water vapor spectra from 296 to 1305 K acquired with a dual-frequency comb spectrometer spanning from 6800 to 7200 c m-1 at a point spacing of 0.0033 c m-1 and absolute frequency accuracy of <3.3 ×10-6c m-1 . Using a multispectral fitting analysis, we show that only the speed-dependent Voigt accurately models this temperature range with a single power-law temperature-scaling exponent for the broadening coefficients. Only the data from the analysis using this profile fall within theoretical predictions, suggesting that this mechanism captures the dominant narrowing physics for these high-temperature conditions.

Rovibrational line-shape parameters for H2 in He and new H2-He potential energy surface

NASA Astrophysics Data System (ADS)

Thibault, Franck; Patkowski, Konrad; Żuchowski, Piotr S.; Jóźwiak, Hubert; Ciuryło, Roman; Wcisło, Piotr

2017-11-01

We report a new H2-He potential energy surface that, with respect to the previous one [Bakr et al.(2013)], covers much larger range of H2 stretching and exhibits more accurate asymptotic behavior for large separations between H2 and He. Close-coupling calculations performed on this improved potential energy surface allow us to provide line shape parameters for H2 between 5 and 2000 K for Raman isotropic Q lines and anisotropic Q lines (or electric quadrupole lines) and for vibrational bands from the ground up to v = 5 and rotational quantum numbers up to j = 5 . The parameters provided include the usual pressure -broadening and -shifting coefficients as well as the real and imaginary part of Dicke contribution to the Hess profile. The latter parameters can be readily implemented in other line-shape profiles like the most recent one of Hartmann and Tran.

An improved computer model for prediction of axial gas turbine performance losses

NASA Technical Reports Server (NTRS)

Jenkins, R. M.

1984-01-01

The calculation model performs a rapid preliminary pitchline optimization of axial gas turbine annular flowpath geometry, as well as an initial estimate of blade profile shapes, given only a minimum of thermodynamic cycle requirements. No geometric parameters need be specified. The following preliminary design data are determined: (1) the optimum flowpath geometry, within mechanical stress limits; (2) initial estimates of cascade blade shapes; and (3) predictions of expected turbine performance. The model uses an inverse calculation technique whereby blade profiles are generated by designing channels to yield a specified velocity distribution on the two walls. Velocity distributions are then used to calculate the cascade loss parameters. Calculated blade shapes are used primarily to determine whether the assumed velocity loadings are physically realistic. Model verification is accomplished by comparison of predicted turbine geometry and performance with an array of seven NASA single-stage axial gas turbine configurations.

Laboratory investigation on the role of tubular shaped micro resonators phononic crystal insertion on the absorption coefficient of profiled sound absorber

NASA Astrophysics Data System (ADS)

Yahya, I.; Kusuma, J. I.; Harjana; Kristiani, R.; Hanina, R.

2016-02-01

This paper emphasizes the influence of tubular shaped microresonators phononic crystal insertion on the sound absorption coefficient of profiled sound absorber. A simple cubic and two different bodies centered cubic phononic crystal lattice model were analyzed in a laboratory test procedure. The experiment was conducted by using transfer function based two microphone impedance tube method refer to ASTM E-1050-98. The results show that sound absorption coefficient increase significantly at the mid and high-frequency band (600 - 700 Hz) and (1 - 1.6 kHz) when tubular shaped microresonator phononic crystal inserted into the tested sound absorber element. The increment phenomena related to multi-resonance effect that occurs when sound waves propagate through the phononic crystal lattice model that produce multiple reflections and scattering in mid and high-frequency band which increases the sound absorption coefficient accordingly

Dynamical behavior of surface tension on rotating fluids in low and microgravity environments

NASA Technical Reports Server (NTRS)

Hung, R. J.; Tsao, Y. D.; Hong, B. B.; Leslie, F. W.

1989-01-01

Consideration is given to the time-dependent evolutions of the free surface profile (bubble shapes) of a cylindrical container, partially filled with a Newtonian fluid of constant density, rotating about its axis of symmetry in low and microgravity environments. The dynamics of the bubble shapes are calculated for four cases: linear time-dependent functions of spin-up and spin-down in low and microgravity, linear time-dependent functions of increasing and decreasing gravity at high and low rotating cylinder speeds, time-dependent step functions of spin-up and spin-down in low gravity, and sinusoidal function oscillation of the gravity environment in high and low rotating cylinder speeds. It is shown that the computer algorithms developed by Hung et al. (1988) may be used to simulate the profile of time-dependent bubble shapes under variations of centrifugal, capillary, and gravity forces.

A comprehensive method for preliminary design optimization of axial gas turbine stages

NASA Technical Reports Server (NTRS)

Jenkins, R. M.

1982-01-01

A method is presented that performs a rapid, reasonably accurate preliminary pitchline optimization of axial gas turbine annular flowpath geometry, as well as an initial estimate of blade profile shapes, given only a minimum of thermodynamic cycle requirements. No geometric parameters need be specified. The following preliminary design data are determined: (1) the optimum flowpath geometry, within mechanical stress limits; (2) initial estimates of cascade blade shapes; (3) predictions of expected turbine performance. The method uses an inverse calculation technique whereby blade profiles are generated by designing channels to yield a specified velocity distribution on the two walls. Velocity distributions are then used to calculate the cascade loss parameters. Calculated blade shapes are used primarily to determine whether the assumed velocity loadings are physically realistic. Model verification is accomplished by comparison of predicted turbine geometry and performance with four existing single stage turbines.

A Formant Range Profile for Singers.

PubMed

Titze, Ingo R; Maxfield, Lynn M; Walker, Megan C

2017-05-01

Vowel selection is important in differentiating between singing styles. The timbre of the vocal instrument, which is related to its frequency spectrum, is governed by both the glottal sound source and the vowel choices made by singers. Consequently, the ability to modify the vowel space is a measure of how successfully a singer can maintain a desired timbre across a range of pitches. Formant range profiles were produced as a means of quantifying this ability. Seventy-seven subjects (including trained and untrained vocalists) participated, producing vowels with three intended mouth shapes: (1) neutral or speech-like, (2) megaphone-shaped (wide open mouth), and (3) inverted-megaphone-shaped (widened oropharynx with moderate mouth opening). The first and second formant frequencies (F 1 and F 2 ) were estimated with fry phonation for each shape and values were plotted in F1-F2 space. By taking four vowels of a quadrangle /i, æ, a, u/, the resulting area was quantified in kHz 2 (kHz squared) as a measure of the subject's ability to modify their vocal tract for spectral differences. Copyright © 2017 The Voice Foundation. Published by Elsevier Inc. All rights reserved.

A FORMANT RANGE PROFILE FOR SINGERS

PubMed Central

Titze, Ingo R.; Maxfield, Lynn; Walker, Megan

2016-01-01

Vowel selection is important in differentiating between singing styles. The timbre of the vocal instrument, which is related to its frequency spectrum, is governed by both the glottal sound source and the vowel choices made by singers. Consequently, the ability to modify the vowel space is a measure of how successfully a singer can maintain a desired timbre across a range of pitches. Formant range profiles (FRPs) were produced as a means of quantifying this ability. 77 subjects (including trained and untrained vocalists) participated, producing vowels with three intended mouth shapes, (1) neutral or speech-like, (2) megaphone-shaped (wide open mouth), and (3) inverted-megaphone-shaped (widened oropharynx with moderate mouth opening). The first and second formant frequencies (F1 and F2) were estimated with fry phonation for each shape and values were plotted in F1–F2 space. By taking four vowels of a quadrangle /i, æ, a, u/, the resulting area was quantified in kHz2 (kHz squared) as a measure of the subject’s ability to modify their vocal tract for spectral differences. PMID:28029556

HST FUV monitoring of TW Hya

NASA Astrophysics Data System (ADS)

Guenther, Hans; Brickhouse, N. S.; Dupree, A. K.; Luna, G.; Schneider, P. C.; Wolk, S. J.

2014-01-01

Classical T Tauri stars (CTTS) show strong, broad and asymmetric FUV emission lines. Neither the width, nor the line profile is understood. Likely, different mechanisms influence the line profile; the best candidates are accretion, winds and stellar activity. We monitored the C IV 1548/1550 Å doublet in the nearby, bright CTTS TW Hya to correlate it with i) the cool wind, as seen in COS NUV Mg II line profiles, ii) the photometric period from joint ground-based monitoring, iii) the accretion rate as determined from the UV continuum and iv) the Ha line profile from independent ground-based observations. The observations span 10 orbits distributed over a few weeks to cover the typical time scales of stellar rotation, accretion and winds. On short time scales (seconds) the variability in the data is compatible with counting statistics when we take certain instrumental effects (the detector dead-time fraction increases when the wavelength calibration lamps are switched on). This rules out any type of coherent accretion shock fluctuation as predicted in some simulations. On longer time scales (days) variability of a factor of 3 in the continuum and similarly massive changes in the line shape are seen. The ratio of the two lines of the doublet indicates that the lines are optically thick, calling into question the idea that the blue-shifted components of the C IV lines are formed in the pre-shock region.

Spectroscopic evidence supporting the gravitational lens hypothesis for 1635+267 A,B

NASA Technical Reports Server (NTRS)

Turner, Edwin L.; Hillenbrand, Lynne A.; Schneider, Donald P.; Hewitt, Jacqueline N.; Burke, Bernard F.

1988-01-01

The gravitational lens hypothesis is tested for 1613+267 A,B by comparing the detailed line widths and shapes of the 2799-A Mg II and semiforbidden 1909-A C-III lines in each component. Following subtraction of an interpolating polynomial fit to the continua and the determination of a single optimum scaling factor (an amplification ratio of 2.83), reasonable agreement between the profiles of both lines in the two composites is obtained. Comparison of these lines to those in an unrelated quasar with a similar redshift and apparent magnitude does not produce a good match. It is suggested that the observed match in the 1635+267 A,B spectra arises from gravitational lensing.

Demographic profile of states with human cloning laws: morality policy meets political economy.

PubMed

Stabile, Bonnie

2007-03-01

This analysis seeks to identify factors that may shape the policy stance - whether restrictive or permissive - that each state in the United States with a human cloning law in place takes toward human therapeutic cloning. The investigation also considers if cloning policy is more the product of morality politics or political economy. Results show that among states with human cloning policies in place, those with a greater biotechnological capacity, more permissive abortion laws, fewer Evangelical Protestants, and higher political liberalism rankings are more likely to have permissive cloning laws. A higher Roman Catholic population is strongly associated with permissive cloning laws, rather than restrictive cloning laws as originally supposed. Factors with morality policy and economic bases were both found to be associated with cloning policy outcomes. Results suggest that morality policies, though distinct in some ways, do share determinants with public policies based on political economy.

Studies of Transitional Flow, Unsteady Separation Phenomena and Particle Induced Augmentation Heating on Ablated Nose Tips.

DTIC Science & Technology

1975-10-01

63 29 Variation of Profile Shape with Time for Axisyinmetric Camphor Models 63 30 The Development of Ablated Nose Shapes Over Which Flow...ablation tests using camphor models and inferred from downrange observation of full scale flight missions. Regions of gross instability on nose...been verified in wind tunnel tests of camphor models where shapes similar to those shown on Figure 29 can be developed under transitional conditions

Contextual and Developmental Differences in the Neural Architecture of Cognitive Control.

PubMed

Petrican, Raluca; Grady, Cheryl L

2017-08-09

Because both development and context impact functional brain architecture, the neural connectivity signature of a cognitive or affective predisposition may similarly vary across different ages and circumstances. To test this hypothesis, we investigated the effects of age and cognitive versus social-affective context on the stable and time-varying neural architecture of inhibition, the putative core cognitive control component, in a subsample ( N = 359, 22-36 years, 174 men) of the Human Connectome Project. Among younger individuals, a neural signature of superior inhibition emerged in both stable and dynamic connectivity analyses. Dynamically, a context-free signature emerged as stronger segregation of internal cognition (default mode) and environmentally driven control (salience, cingulo-opercular) systems. A dynamic social-affective context-specific signature was observed most clearly in the visual system. Stable connectivity analyses revealed both context-free (greater default mode segregation) and context-specific (greater frontoparietal segregation for higher cognitive load; greater attentional and environmentally driven control system segregation for greater reward value) signatures of inhibition. Superior inhibition in more mature adulthood was typified by reduced segregation in the default network with increasing reward value and increased ventral attention but reduced cingulo-opercular and subcortical system segregation with increasing cognitive load. Failure to evidence this neural profile after the age of 30 predicted poorer life functioning. Our results suggest that distinguishable neural mechanisms underlie individual differences in cognitive control during different young adult stages and across tasks, thereby underscoring the importance of better understanding the interplay among dispositional, developmental, and contextual factors in shaping adaptive versus maladaptive patterns of thought and behavior. SIGNIFICANCE STATEMENT The brain's functional architecture changes across different contexts and life stages. To test whether the neural signature of a trait similarly varies, we investigated cognitive versus social-affective context effects on the stable and time-varying neural architecture of inhibition during a period of neurobehavioral fine-tuning (age 22-36 years). Younger individuals with superior inhibition showed distinguishable context-free and context-specific neural profiles, evidenced in both static and dynamic connectivity analyses. More mature individuals with superior inhibition evidenced only context-specific profiles, revealed in the static connectivity patterns linked to increased reward or cognitive load. Delayed expression of this profile predicted poorer life functioning. Our results underscore the importance of understanding the interplay among dispositional, developmental, and contextual factors in shaping behavior. Copyright © 2017 the authors 0270-6474/17/377711-16$15.00/0.

Ultrahigh-resolution spectroscopy with atomic or molecular dark resonances: Exact steady-state line shapes and asymptotic profiles in the adiabatic pulsed regime

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zanon-Willette, Thomas; Clercq, Emeric de; Arimondo, Ennio

2011-12-15

Exact and asymptotic line shape expressions are derived from the semiclassical density matrix representation describing a set of closed three-level {Lambda} atomic or molecular states including decoherences, relaxation rates, and light shifts. An accurate analysis of the exact steady-state dark-resonance profile describing the Autler-Townes doublet, the electromagnetically induced transparency or coherent population trapping resonance, and the Fano-Feshbach line shape leads to the linewidth expression of the two-photon Raman transition and frequency shifts associated to the clock transition. From an adiabatic analysis of the dynamical optical Bloch equations in the weak field limit, a pumping time required to efficiently trap amore » large number of atoms into a coherent superposition of long-lived states is established. For a highly asymmetrical configuration with different decay channels, a strong two-photon resonance based on a lower states population inversion is established when the driving continuous-wave laser fields are greatly unbalanced. When time separated resonant two-photon pulses are applied in the adiabatic pulsed regime for atomic or molecular clock engineering, where the first pulse is long enough to reach a coherent steady-state preparation and the second pulse is very short to avoid repumping into a new dark state, dark-resonance fringes mixing continuous-wave line shape properties and coherent Ramsey oscillations are created. Those fringes allow interrogation schemes bypassing the power broadening effect. Frequency shifts affecting the central clock fringe computed from asymptotic profiles and related to the Raman decoherence process exhibit nonlinear shapes with the three-level observable used for quantum measurement. We point out that different observables experience different shifts on the lower-state clock transition.« less

Structure and dynamics of H2+ near the dissociation threshold: A combined experimental and computational investigation

NASA Astrophysics Data System (ADS)

Beyer, Maximilian; Merkt, Frédéric

2016-12-01

The pulsed-field-ionization zero-kinetic-energy photoelectron spectrum of H2 has been recorded in the vicinity of the dissociative-ionization threshold following three-photon excitation via selected rotational levels of the B1 Σu+ (v = 19) and H ‾ 1 Σg+ (v = 11) intermediate states. The spectra consist of transitions to bound levels of the X+2 Σg+ state of H2+ with v+ in the range 14-19 and N+ in the range 0-9, of the A+2 Σu+ state with v+ = 0 and N+ = 0-2, and of shape resonances corresponding to the X+(v+ = 17, N+ = 7) and X+(v+ = 18, N+ = 4) quasibound levels. Calculations of the level structure of H2+ have been carried out and the influence of adiabatic, nonadiabatic, relativistic and radiative corrections on the positions of these levels, and in the case of the shape resonances also on their widths, has been investigated. Different methods of calculating the widths and profiles of the shape resonances have been tested for comparison with the experimental observations. Slow oscillations of the dissociative-ionization yield have been observed and reflect, in first approximation, the Franck-Condon factors of the X+, A+ ← H ‾ bound - free transitions.

Assessment of the setup dependence of detector response functions for mega-voltage linear accelerators

PubMed Central

Fox, Christopher; Simon, Tom; Simon, Bill; Dempsey, James F.; Kahler, Darren; Palta, Jatinder R.; Liu, Chihray; Yan, Guanghua

2010-01-01

Purpose: Accurate modeling of beam profiles is important for precise treatment planning dosimetry. Calculated beam profiles need to precisely replicate profiles measured during machine commissioning. Finite detector size introduces perturbations into the measured profiles, which, in turn, impact the resulting modeled profiles. The authors investigate a method for extracting the unperturbed beam profiles from those measured during linear accelerator commissioning. Methods: In-plane and cross-plane data were collected for an Elekta Synergy linac at 6 MV using ionization chambers of volume 0.01, 0.04, 0.13, and 0.65 cm3 and a diode of surface area 0.64 mm2. The detectors were orientated with the stem perpendicular to the beam and pointing away from the gantry. Profiles were measured for a 10×10 cm2 field at depths ranging from 0.8 to 25.0 cm and SSDs from 90 to 110 cm. Shaping parameters of a Gaussian response function were obtained relative to the Edge detector. The Gaussian function was deconvolved from the measured ionization chamber data. The Edge detector profile was taken as an approximation to the true profile, to which deconvolved data were compared. Data were also collected with CC13 and Edge detectors for additional fields and energies on an Elekta Synergy, Varian Trilogy, and Siemens Oncor linear accelerator and response functions obtained. Response functions were compared as a function of depth, SSD, and detector scan direction. Variations in the shaping parameter were introduced and the effect on the resulting deconvolution profiles assessed. Results: Up to 10% setup dependence in the Gaussian shaping parameter occurred, for each detector for a particular plane. This translated to less than a ±0.7 mm variation in the 80%–20% penumbral width. For large volume ionization chambers such as the FC65 Farmer type, where the cavity length to diameter ratio is far from 1, the scan direction produced up to a 40% difference in the shaping parameter between in-plane and cross-plane measurements. This is primarily due to the directional difference in penumbral width measured by the FC65 chamber, which can more than double in profiles obtained with the detector stem parallel compared to perpendicular to the scan direction. For the more symmetric CC13 chamber the variation was only 3% between in-plane and cross-plane measurements. Conclusions: The authors have shown that the detector response varies with detector type, depth, SSD, and detector scan direction. In-plane vs cross-plane scanning can require calculation of a direction dependent response function. The effect of a 10% overall variation in the response function, for an ionization chamber, translates to a small deviation in the penumbra from that of the Edge detector measured profile when deconvolved. Due to the uncertainties introduced by deconvolution the Edge detector would be preferable in obtaining an approximation of the true profile, particularly for field sizes where the energy dependence of the diode can be neglected. However, an averaged response function could be utilized to provide a good approximation of the true profile for large ionization chambers and for larger fields for which diode detectors are not recommended. PMID:20229856

Genome-Wide Characterization and Expression Profiling of the AUXIN RESPONSE FACTOR (ARF) Gene Family in Eucalyptus grandis

PubMed Central

Yu, Hong; Soler, Marçal; Mila, Isabelle; San Clemente, Hélène; Savelli, Bruno; Dunand, Christophe; Paiva, Jorge A. P.; Myburg, Alexander A.; Bouzayen, Mondher; Grima-Pettenati, Jacqueline; Cassan-Wang, Hua

2014-01-01

Auxin is a central hormone involved in a wide range of developmental processes including the specification of vascular stem cells. Auxin Response Factors (ARF) are important actors of the auxin signalling pathway, regulating the transcription of auxin-responsive genes through direct binding to their promoters. The recent availability of the Eucalyptus grandis genome sequence allowed us to examine the characteristics and evolutionary history of this gene family in a woody plant of high economic importance. With 17 members, the E. grandis ARF gene family is slightly contracted, as compared to those of most angiosperms studied hitherto, lacking traces of duplication events. In silico analysis of alternative transcripts and gene truncation suggested that these two mechanisms were preeminent in shaping the functional diversity of the ARF family in Eucalyptus. Comparative phylogenetic analyses with genomes of other taxonomic lineages revealed the presence of a new ARF clade found preferentially in woody and/or perennial plants. High-throughput expression profiling among different organs and tissues and in response to environmental cues highlighted genes expressed in vascular cambium and/or developing xylem, responding dynamically to various environmental stimuli. Finally, this study allowed identification of three ARF candidates potentially involved in the auxin-regulated transcriptional program underlying wood formation. PMID:25269088

The kinematics of the molecular gas in Centaurus A

NASA Technical Reports Server (NTRS)

Quillen, A. C.; De Zeeuw, P. T.; Phinney, E. S.; Phillips, T. G.

1992-01-01

The CO (2-1) emission along the inner dust lane of Centaurus A, observed with the Caltech Submillimeter Observatory on Mauna Kea, shows the molecular gas to be in a thin disk, with a velocity dispersion of only about 10 km/s. The observed line profiles are broadened considerably due to beam smearing of the gas velocity field. The profile shapes are inconsistent with planar circular and noncircular motion. However, a warped disk in a prolate potential provides a good fit to the profile shapes. The morphology and kinematics of the molecular gas is similar to that of the ionized material, seen in H-alpha. The best-fitting warped disk model not only matches the optical appearance of the dust lane but also agrees with the large-scale map of the CO emission and is consistent with H I measurements at larger radii.

Noise suppression due to annulus shaping of an inverted-velocity-profile coaxial nozzle. [supersonic cruise aircraft

NASA Technical Reports Server (NTRS)

Goodykoontz, J.; Vonglahn, U.

1980-01-01

An inverted velocity profile coaxial nozzle for use with supersonic cruise aircraft produces less jet noise than an equivalent conical nozzle. Furthermore, decreasing the annulus height (increasing radius ratio with constant flow) results in further noise reduction benefits. The annulus shape (height) was varied by an eccentric mounting of the annular nozzle with respect to a conical core nozzle. Acoustic measurements were made in the flyover plane below the narrowest portion of the annulus and at 90 deg and 180 deg from this point. The model-scale spectra are scaled up to engine size (1.07 m diameter) and the perceived noise levels for the eccentric and baseline concentric inverted velocity profile coaxial nozzles are compared over a range of operating conditions. The implications of the acoustic benefits derived with the eccentric nozzle to practical applications are discussed.

Determination of optimum fin profile for a zero-G capillary drained condenser

NASA Technical Reports Server (NTRS)

Mccormick, John A.; Valenzuela, Javier A.; Choudhury, Dipanker

1990-01-01

This paper presents the analytical formulation and numerical results for heat transfer in a high heat flux condenser that relies on capillary flow along shaped fins (Gregorig surfaces) and a drainage network embedded in the condenser walls. Results are shown for a variety of fin profile shapes in order to show the geometric trade-offs involved in seeking a maximum effective heat transfer coefficient for the fin. Predictions of the model show excellent agreement with previously reported measurements for steam. Based on this work, a profile has been selected for a 2 kW ammonia condenser currently under development for use in space. In that design the fin half width is 0.5 mm and the model predicts a heat transfer coefficient referred to the base of the fin of 9 W/sq cm deg C for a heat flux of 10/W sq cm at the base.

Exact analytical modeling of lightwave propagation in planar media with arbitrarily graded index profiles

NASA Astrophysics Data System (ADS)

Krapez, J.-C.

2018-02-01

Applying the Darboux transformation in the optical-depth space allows building infinite chains of exact analytical solutions of the electromagnetic (EM) fields in planar 1D-graded dielectrics. As a matter of fact, infinite chains of solvable admittance profiles (e.g. refractive-index profiles, in the case of non-magnetic materials), together with the related EM fields are simultaneously and recursively obtained. The whole procedure has received the name "PROFIDT method" for PROperty and FIeld Darboux Transformation method. By repeating the Darboux transformations we can find out progressively more complex profiles and their EM solutions. An alternative is to stop after the first step and settle for a particular class of four-parameter admittance profiles that were dubbed of "sech(ξ)-type". These profiles are highly flexible. For this reason, they can be used as elementary bricks for building and modeling profiles of arbitrary shape. In addition, the corresponding transfer matrix involves only elementary functions. The sub-class of "sech(ξ)-type" profiles with horizontal end-slopes (S-shaped function) is particularly interesting: these can be used for high-level modeling of piecewise-sigmoidal refractive-index profiles encountered in various photonic devices such as matchinglayers, antireflection layers, rugate filters, chirped mirrors and photonic crystals. These simple analytical tools also allow exploring the fascinating properties of a new kind of structure, namely smooth quasicrystals. They can also be applied to model propagation of other types of waves in graded media such as acoustic waves and electric waves in tapered transmission lines.

Shape Optimization for Navier-Stokes Equations with Algebraic Turbulence Model: Numerical Analysis and Computation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Haslinger, Jaroslav, E-mail: hasling@karlin.mff.cuni.cz; Stebel, Jan, E-mail: stebel@math.cas.cz

2011-04-15

We study the shape optimization problem for the paper machine headbox which distributes a mixture of water and wood fibers in the paper making process. The aim is to find a shape which a priori ensures the given velocity profile on the outlet part. The mathematical formulation leads to the optimal control problem in which the control variable is the shape of the domain representing the header, the state problem is represented by the generalized Navier-Stokes system with nontrivial boundary conditions. This paper deals with numerical aspects of the problem.

Informing Comprehensive HIV Prevention: A Situational Analysis of the HIV Prevention and Care Context, North West Province South Africa

PubMed Central

Lippman, Sheri A.; Treves-Kagan, Sarah; Gilvydis, Jennifer M.; Naidoo, Evasen; Khumalo-Sakutukwa, Gertrude; Darbes, Lynae; Raphela, Elsie; Ntswane, Lebogang; Barnhart, Scott

2014-01-01

Objective Building a successful combination prevention program requires understanding the community’s local epidemiological profile, the social community norms that shape vulnerability to HIV and access to care, and the available community resources. We carried out a situational analysis in order to shape a comprehensive HIV prevention program that address local barriers to care at multiple contextual levels in the North West Province of South Africa. Method The situational analysis was conducted in two sub-districts in 2012 and guided by an adaptation of WHO’s Strategic Approach, a predominantly qualitative method, including observation of service delivery points and in-depth interviews and focus groups with local leaders, providers, and community members, in order to recommend context-specific HIV prevention strategies. Analysis began during fieldwork with nightly discussions of findings and continued with coding original textual data from the fieldwork notebooks and a select number of recorded interviews. Results We conducted over 200 individual and group interviews and gleaned four principal social barriers to HIV prevention and care, including: HIV fatalism, traditional gender norms, HIV-related stigma, and challenges with communication around HIV, all of which fuel the HIV epidemic. At the different levels of response needed to stem the epidemic, we found evidence of national policies and programs that are mitigating the social risk factors but little community-based responses that address social risk factors to HIV. Conclusions Understanding social and structural barriers to care helped shape our comprehensive HIV prevention program, which address the four ‘themes’ identified into each component of the program. Activities are underway to engage communities, offer community-based testing in high transmission areas, community stigma reduction, and a positive health, dignity and prevention program for stigma reduction and improve communication skills. The situational analysis process successfully shaped key programmatic decisions and cultivated a deeper collaboration with local stakeholders to support program implementation. PMID:25028976

Informing comprehensive HIV prevention: a situational analysis of the HIV prevention and care context, North West Province South Africa.

PubMed

Lippman, Sheri A; Treves-Kagan, Sarah; Gilvydis, Jennifer M; Naidoo, Evasen; Khumalo-Sakutukwa, Gertrude; Darbes, Lynae; Raphela, Elsie; Ntswane, Lebogang; Barnhart, Scott

2014-01-01

Building a successful combination prevention program requires understanding the community's local epidemiological profile, the social community norms that shape vulnerability to HIV and access to care, and the available community resources. We carried out a situational analysis in order to shape a comprehensive HIV prevention program that address local barriers to care at multiple contextual levels in the North West Province of South Africa. The situational analysis was conducted in two sub-districts in 2012 and guided by an adaptation of WHO's Strategic Approach, a predominantly qualitative method, including observation of service delivery points and in-depth interviews and focus groups with local leaders, providers, and community members, in order to recommend context-specific HIV prevention strategies. Analysis began during fieldwork with nightly discussions of findings and continued with coding original textual data from the fieldwork notebooks and a select number of recorded interviews. We conducted over 200 individual and group interviews and gleaned four principal social barriers to HIV prevention and care, including: HIV fatalism, traditional gender norms, HIV-related stigma, and challenges with communication around HIV, all of which fuel the HIV epidemic. At the different levels of response needed to stem the epidemic, we found evidence of national policies and programs that are mitigating the social risk factors but little community-based responses that address social risk factors to HIV. Understanding social and structural barriers to care helped shape our comprehensive HIV prevention program, which address the four 'themes' identified into each component of the program. Activities are underway to engage communities, offer community-based testing in high transmission areas, community stigma reduction, and a positive health, dignity and prevention program for stigma reduction and improve communication skills. The situational analysis process successfully shaped key programmatic decisions and cultivated a deeper collaboration with local stakeholders to support program implementation.

Airfoil shape for a turbine nozzle

DOEpatents

Burdgick, Steven Sebastian; Patik, Joseph Francis; Itzel, Gary Michael

2002-01-01

A first-stage nozzle vane includes an airfoil having a profile according to Table I. The annulus profile of the hot gas path is defined in conjunction with the airfoil profile and the profile of the inner and outer walls by the Cartesian coordinate values given in Tables I and II, respectively. The airfoil is a three-dimensional bowed design, both in the airfoil body and in the trailing edge. The airfoil is steam and air-cooled by flowing cooling mediums through cavities extending in the vane between inner and outer walls.

Constraints on Porosity and Mass Loss in O-star Winds from the Modeling of X-ray Emission Line Profile Shapes

NASA Technical Reports Server (NTRS)

Leutenegger, Maurice A.; Cohen, David H.; Sundqvist, Jon O.; Owocki, Stanley P.

2013-01-01

We fit X-ray emission line profiles in high resolution XMM-Newton and Chandra grating spectra of the early O supergiant Zeta Pup with models that include the effects of porosity in the stellar wind. We explore the effects of porosity due to both spherical and flattened clumps. We find that porosity models with flattened clumps oriented parallel to the photosphere provide poor fits to observed line shapes. However, porosity models with isotropic clumps can provide acceptable fits to observed line shapes, but only if the porosity effect is moderate. We quantify the degeneracy between porosity effects from isotropic clumps and the mass-loss rate inferred from the X-ray line shapes, and we show that only modest increases in the mass-loss rate (40%) are allowed if moderate porosity effects (h(sub infinity) less than approximately R(sub *)) are assumed to be important. Large porosity lengths, and thus strong porosity effects, are ruled out regardless of assumptions about clump shape. Thus, X-ray mass-loss rate estimates are relatively insensitive to both optically thin and optically thick clumping. This supports the use of X-ray spectroscopy as a mass-loss rate calibration for bright, nearby O stars

Shape-programmable magnetic soft matter

PubMed Central

Lum, Guo Zhan; Ye, Zhou; Dong, Xiaoguang; Marvi, Hamid; Erin, Onder; Hu, Wenqi; Sitti, Metin

2016-01-01

Shape-programmable matter is a class of active materials whose geometry can be controlled to potentially achieve mechanical functionalities beyond those of traditional machines. Among these materials, magnetically actuated matter is particularly promising for achieving complex time-varying shapes at small scale (overall dimensions smaller than 1 cm). However, previous work can only program these materials for limited applications, as they rely solely on human intuition to approximate the required magnetization profile and actuating magnetic fields for their materials. Here, we propose a universal programming methodology that can automatically generate the required magnetization profile and actuating fields for soft matter to achieve new time-varying shapes. The universality of the proposed method can therefore inspire a vast number of miniature soft devices that are critical in robotics, smart engineering surfaces and materials, and biomedical devices. Our proposed method includes theoretical formulations, computational strategies, and fabrication procedures for programming magnetic soft matter. The presented theory and computational method are universal for programming 2D or 3D time-varying shapes, whereas the fabrication technique is generic only for creating planar beams. Based on the proposed programming method, we created a jellyfish-like robot, a spermatozoid-like undulating swimmer, and an artificial cilium that could mimic the complex beating patterns of its biological counterpart. PMID:27671658

Shape-programmable magnetic soft matter.

PubMed

Lum, Guo Zhan; Ye, Zhou; Dong, Xiaoguang; Marvi, Hamid; Erin, Onder; Hu, Wenqi; Sitti, Metin

2016-10-11

Shape-programmable matter is a class of active materials whose geometry can be controlled to potentially achieve mechanical functionalities beyond those of traditional machines. Among these materials, magnetically actuated matter is particularly promising for achieving complex time-varying shapes at small scale (overall dimensions smaller than 1 cm). However, previous work can only program these materials for limited applications, as they rely solely on human intuition to approximate the required magnetization profile and actuating magnetic fields for their materials. Here, we propose a universal programming methodology that can automatically generate the required magnetization profile and actuating fields for soft matter to achieve new time-varying shapes. The universality of the proposed method can therefore inspire a vast number of miniature soft devices that are critical in robotics, smart engineering surfaces and materials, and biomedical devices. Our proposed method includes theoretical formulations, computational strategies, and fabrication procedures for programming magnetic soft matter. The presented theory and computational method are universal for programming 2D or 3D time-varying shapes, whereas the fabrication technique is generic only for creating planar beams. Based on the proposed programming method, we created a jellyfish-like robot, a spermatozoid-like undulating swimmer, and an artificial cilium that could mimic the complex beating patterns of its biological counterpart.

Shape-programmable magnetic soft matter

NASA Astrophysics Data System (ADS)

Zhan Lum, Guo; Ye, Zhou; Dong, Xiaoguang; Marvi, Hamid; Erin, Onder; Hu, Wenqi; Sitti, Metin

2016-10-01

Shape-programmable matter is a class of active materials whose geometry can be controlled to potentially achieve mechanical functionalities beyond those of traditional machines. Among these materials, magnetically actuated matter is particularly promising for achieving complex time-varying shapes at small scale (overall dimensions smaller than 1 cm). However, previous work can only program these materials for limited applications, as they rely solely on human intuition to approximate the required magnetization profile and actuating magnetic fields for their materials. Here, we propose a universal programming methodology that can automatically generate the required magnetization profile and actuating fields for soft matter to achieve new time-varying shapes. The universality of the proposed method can therefore inspire a vast number of miniature soft devices that are critical in robotics, smart engineering surfaces and materials, and biomedical devices. Our proposed method includes theoretical formulations, computational strategies, and fabrication procedures for programming magnetic soft matter. The presented theory and computational method are universal for programming 2D or 3D time-varying shapes, whereas the fabrication technique is generic only for creating planar beams. Based on the proposed programming method, we created a jellyfish-like robot, a spermatozoid-like undulating swimmer, and an artificial cilium that could mimic the complex beating patterns of its biological counterpart.

Aerodynamically-Actuated Radical Shape-Change Concept

NASA Technical Reports Server (NTRS)

Ivanco, Thomas G.; Ivanco, Marie L.; Ancel, Ersin; Grubb, Amanda L.; Prasad, Supranamaaya

2017-01-01

Aerodynamically-actuated radical shape change (AARSC) is a novel concept that enables flight vehicles to conduct a mission profile containing radically different flight regimes while possibly mitigating the typical penalties incurred by radical geometric change. Weight penalties are mitigated by utilizing a primary flight control to generate aerodynamic loads that then drive a shape-change actuation. The flight mission profile used to analyze the AARSC concept is that of a transport aircraft that cruises at a lower altitude than typical transports. Based upon a preliminary analysis, substantial fuel savings are realized for mission ranges below 2000 NM by comparison to a state-of-the-art baseline, with an increasing impact as mission range is reduced. The predicted savings are so significant at short-haul ranges that the shape-change concept rivals the fuel-burn performance of turboprop aircraft while completing missions in less time than typical jet aircraft. Lower-altitude cruise has also been sought after in recent years for environmental benefits, however, the performance penalty to conventional aircraft was prohibitive. AARSC may enable the opportunity to realize the environmental benefits of lower-altitude emissions coupled with mission fuel savings. The findings of this study also reveal that the AARSC concept appears to be controllable, turbulence susceptibility is likely not an issue, and the shape change concept appears to be mechanically and aerodynamically feasible.

Vertical Structure of Ice Cloud Layers From CloudSat and CALIPSO Measurements and Comparison to NICAM Simulations

NASA Technical Reports Server (NTRS)

Ham, Seung-Hee; Sohn, Byung-Ju; Kato, Seiji; Satoh, Masaki

2013-01-01

The shape of the vertical profile of ice cloud layers is examined using 4 months of CloudSat and Cloud-Aerosol Lidar and Infrared Pathfinder Satellite Observation (CALIPSO) global measurements taken on January, April, July, and October 2007. Ice clouds are selected using temperature profiles when the cloud base is located above the 253K temperature level. The obtained ice water content (IWC), effective radius, or extinction coefficient profiles are normalized by their layer mean values and are expressed in the normalized vertical coordinate, which is defined as 0 and 1 at the cloud base and top heights, respectively. Both CloudSat and CALIPSO observations show that the maximum in the IWC and extinction profiles shifts toward the cloud bottom, as the cloud depth increases. In addition, clouds with a base reaching the surface in a high-latitude region show that the maximum peak of the IWC and extinction profiles occurs near the surface, which is presumably due to snow precipitation. CloudSat measurements show that the seasonal difference in normalized cloud vertical profiles is not significant, whereas the normalized cloud vertical profile significantly varies depending on the cloud type and the presence of precipitation. It is further examined if the 7 day Nonhydrostatic Icosahedral Atmospheric Model (NICAM) simulation results from 25 December 2006 to 1 January 2007 generate similar cloud profile shapes. NICAM IWC profiles also show maximum peaks near the cloud bottom for thick cloud layers and maximum peaks at the cloud bottom for low-level clouds near the surface. It is inferred that oversized snow particles in the NICAM cloud scheme produce a more vertically inhomogeneous IWC profile than observations due to quick sedimentation.

Production of Lightning NO(x) and its Vertical Distribution Calculated from 3-D Cloud-scale Chemical Transport Model Simulations

NASA Technical Reports Server (NTRS)

Ott, Lesley; Pickering, Kenneth; Stenchikov, Georgiy; Allen, Dale; DeCaria, Alex; Ridley, Brian; Lin, Ruei-Fong; Lang, Steve; Tao, Wei-Kuo

2009-01-01

A 3-D cloud scale chemical transport model that includes a parameterized source of lightning NO(x), based on observed flash rates has been used to simulate six midlatitude and subtropical thunderstorms observed during four field projects. Production per intracloud (P(sub IC) and cloud-to-ground (P(sub CG)) flash is estimated by assuming various values of P(sub IC) and P(sub CG) for each storm and determining which production scenario yields NO(x) mixing ratios that compare most favorably with in-cloud aircraft observations. We obtain a mean P(sub CG) value of 500 moles NO (7 kg N) per flash. The results of this analysis also suggest that on average, P(sub IC) may be nearly equal to P(sub CG), which is contrary to the common assumption that intracloud flashes are significantly less productive of NO than are cloud-to-ground flashes. This study also presents vertical profiles of the mass of lightning NO(x), after convection based on 3-D cloud-scale model simulations. The results suggest that following convection, a large percentage of lightning NO(x), remains in the middle and upper troposphere where it originated, while only a small percentage is found near the surface. The results of this work differ from profiles calculated from 2-D cloud-scale model simulations with a simpler lightning parameterization that were peaked near the surface and in the upper troposphere (referred to as a "C-shaped" profile). The new model results (a backward C-shaped profile) suggest that chemical transport models that assume a C-shaped vertical profile of lightning NO(x) mass may place too much mass neat the surface and too little in the middle troposphere.

The Relationship between Ionospheric Slab Thickness and the Peak Density Height, hmF2

NASA Astrophysics Data System (ADS)

Meehan, J.; Sojka, J. J.

2017-12-01

The electron density profile is one of the most critical elements in the ionospheric modeling-related applications today. Ionosphere parameters, hmF2, the height of the peak density layer, and slab thickness, the ratio of the total electron content, TEC, to the peak density value, NmF2, are generally obtained from any global sounding observation network and are easily incorporated into models, theoretical or empirical, as numerical representations. Slab thickness is a convenient one-parameter summary of the electron density profile and can relate a variety of elements of interest that effect the overall electron profile shape, such as the neutral and ionospheric temperatures and gradients, the ionospheric composition, and dynamics. Using ISR data from the 2002 Millstone Hill ISR data campaign, we found, for the first time, slab thickness to be correlated to hmF2. For this, we introduce a new ionospheric index, k, which ultimately relates electron density parameters and can be a very useful tool for describing the topside ionosphere shape. Our study is an initial one location, one season, 30-day study, and future work is needed to verify the robustness of our claim. Generally, the ionospheric profile shape, requires knowledge of several ionospheric parameters: electron, ion and neutral temperatures, ion composition, electric fields, and neutral winds, and is dependent upon seasons, local time, location, and the level of solar and geomagnetic activity; however, with this new index, only readily-available, ionospheric density information is needed. Such information, as used in this study, is obtained from a bottomside electron density profile provided by an ionosonde, and TEC data provided by a local, collocated GPS receiver.

Iceberg and ice-keel ploughmarks on the Gdansk-Gotland Sill (south-eastern Baltic Sea)

NASA Astrophysics Data System (ADS)

Dorokhov, D. V.; Dorokhova, E. V.; Sivkov, V. V.

2018-02-01

New interpretation of the undulating moraine relief of the Gdansk-Gotland Sill, Baltic Sea is proposed. Relict iceberg and ice-keel ploughmarks were observed based on the integration of recently acquired side-scan sonar, multi-beam, single-beam and lithological data. The most likely time of their formation is the period of fast Scandinavian sheet retreat occurring from approximately 13.2 to 11.7 ka. Weak erosional-accumulative processes on the sill from 11.7 ka until the present favoured preservation of the iceberg ploughmarks. The predominant directions of the ploughmarks (north-south and northwest-southeast) coincide with the major iceberg (ice) drift direction from the Scandinavian ice sheet. Furrow width varies from 1 to 300 m with a main width of 20-60 m in a depth range of 1 to 10 m (mostly 2-4 m depth). The ploughmarks are flanked by side ridges 0.5-2 m high, and there is a push mound at the end of some furrows. Three types of cross-sectional furrow profiles have been distinguished: V-shaped cross-section profiles would have been formed by a peaked iceberg keel, U-shaped profiles by a flat keel, and W-shaped profiles by double-keel icebergs (ice ridges). The wide local depressions at the end of ploughmarks could have been formed during periods of fast falling of the Baltic Ice Lake water level, when the ice ridges (stamukhi) or icebergs could ground into the seafloor.

Finger tracking for hand-held device interface using profile-matching stereo vision

NASA Astrophysics Data System (ADS)

Chang, Yung-Ping; Lee, Dah-Jye; Moore, Jason; Desai, Alok; Tippetts, Beau

2013-01-01

Hundreds of millions of people use hand-held devices frequently and control them by touching the screen with their fingers. If this method of operation is being used by people who are driving, the probability of deaths and accidents occurring substantially increases. With a non-contact control interface, people do not need to touch the screen. As a result, people will not need to pay as much attention to their phones and thus drive more safely than they would otherwise. This interface can be achieved with real-time stereovision. A novel Intensity Profile Shape-Matching Algorithm is able to obtain 3-D information from a pair of stereo images in real time. While this algorithm does have a trade-off between accuracy and processing speed, the result of this algorithm proves the accuracy is sufficient for the practical use of recognizing human poses and finger movement tracking. By choosing an interval of disparity, an object at a certain distance range can be segmented. In other words, we detect the object by its distance to the cameras. The advantage of this profile shape-matching algorithm is that detection of correspondences relies on the shape of profile and not on intensity values, which are subjected to lighting variations. Based on the resulting 3-D information, the movement of fingers in space from a specific distance can be determined. Finger location and movement can then be analyzed for non-contact control of hand-held devices.

Shape Optimization for Navier-Stokes Equations with Algebraic Turbulence Model: Existence Analysis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bulicek, Miroslav; Haslinger, Jaroslav; Malek, Josef

2009-10-15

We study a shape optimization problem for the paper machine headbox which distributes a mixture of water and wood fibers in the paper making process. The aim is to find a shape which a priori ensures the given velocity profile on the outlet part. The mathematical formulation leads to an optimal control problem in which the control variable is the shape of the domain representing the header, the state problem is represented by a generalized stationary Navier-Stokes system with nontrivial mixed boundary conditions. In this paper we prove the existence of solutions both to the generalized Navier-Stokes system and tomore » the shape optimization problem.« less

EFFECTS OF LEAF AREA PROFILES AND CANOPY STRATIFICATION ON SIMULATED ENERGY FLUXES: THE PROBLEM OF VERTICAL SPATIAL SCALE. (R827676)

EPA Science Inventory

We investigated the effects of the shape of leaf area profiles and the number of canopy layers on simulated sensible and latent heat fluxes using a gradient diffusion-based biometeorological model. Three research questions were addressed through simulation experiments: (1) Given ...

Drive Beam Shaping and Witness Bunch Generation for the Plasma Wakefield Accelerator

DOE Office of Scientific and Technical Information (OSTI.GOV)

England, R. J.; Frederico, J.; Hogan, M. J.

2010-11-04

High transformer ratio operation of the plasma wake field accelerator requires a tailored drive beam current profile followed by a short witness bunch. We discuss techniques for generating the requisite dual bunches and for obtaining the desired drive beam profile, with emphasis on the FACET experiment at SLAC National Accelerator Laboratory.

The Strong Ring: A Basic Interest Model of Occupational Structure

ERIC Educational Resources Information Center

Armstrong, Patrick Ian; Smith, Thomas J.; Donnay, David A. C.; Rounds, James

2004-01-01

A classification system and spatial map of occupations were developed using the Basic Interest Scale profiles of 198 occupational incumbent samples (31,010 women; 32,421 men) from the Strong Interest Inventory. Profile shape was found to be similar for incumbents of both genders, allowing for an analysis of combined-gender samples. Using…

The impact of shape memory test on degradation profile of a bioresorbable polymer.

PubMed

Musioł, Marta; Jurczyk, Sebastian; Kwiecień, Michał; Smola-Dmochowska, Anna; Domański, Marian; Janeczek, Henryk; Włodarczyk, Jakub; Klim, Magdalena; Rydz, Joanna; Kawalec, Michał; Sobota, Michał

2018-05-01

The semicrystalline poly(L-lactide) (PLLA) belongs to the materials with shape memory effect (SME) and as a bioresorbable and biocompatible polymer it have found many applications in medical and pharmaceutical field. Assessment of the SME impact on the polymer degradation profile plays crucial role in applications such as drug release systems or in regenerative medicine. Herein, the results of in vitro degradation studies of PLLA samples after SME full test cycle are presented. The samples were loaded and deformed in two manners: progressive and non-progressive. The performed experiments illustrate also influence of the material mechanical damages, caused e.g. during incorrect implantation of PLLA product, on hydrolytic degradation profile. Apparently, degradation profiles are significantly different for the material which was not subjected to the deformation and the deformed ones. The materials after deformation of 50% (in SME cycle) was characterized by non-reversible morphology changes. The effect was observed in deformed samples during the SME test which were carried out ten times. Copyright © 2018 Elsevier Ltd. All rights reserved.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Garnier, D. T.; Mauel, M. E.; Roberts, T. M.

Here, we report measurements of the turbulent evolution of the plasma density profile following the fast injection of lithium pellets into the Levitated Dipole Experiment (LDX) [Boxer et al., Nat. Phys. 6, 207 (2010)]. As the pellet passes through the plasma, it provides a significant internal particle source and allows investigation of density profile evolution, turbulent relaxation, and turbulent fluctuations. The total electron number within the dipole plasma torus increases by more than a factor of three, and the central density increases by more than a factor of five. During these large changes in density, the shape of the densitymore » profile is nearly “stationary” such that the gradient of the particle number within tubes of equal magnetic flux vanishes. In comparison to the usual case, when the particle source is neutral gas at the plasma edge, the internal source from the pellet causes the toroidal phase velocity of the fluctuations to reverse and changes the average particle flux at the plasma edge. An edge particle source creates an inward turbulent pinch, but an internal particle source increases the outward turbulent particle flux. Statistical properties of the turbulence are measured by multiple microwave interferometers and by an array of probes at the edge. The spatial structures of the largest amplitude modes have long radial and toroidal wavelengths. Estimates of the local and toroidally averaged turbulent particle flux show intermittency and a non-Gaussian probability distribution function. The measured fluctuations, both before and during pellet injection, have frequency and wave number dispersion consistent with theoretical expectations for interchange and entropy modes excited within a dipole plasma torus having warm electrons and cool ions.« less

Profiles in Renewable Energy: Case Studies of Successful Utility-Sector

Science.gov Websites

Shape of Renewable Energy Technologies Today Biomass Wood-Burning Plant Reduces Air Pollution Kettle Economical Altamont Pass Windplants U.S. Windpower, Inc. For More Information The Shape of Renewable Energy temperatures >175 degrees C), which rely on flashing the hot water to steam, and binary plants (for resource

Flat profile laser beam shaper

DOEpatents

Johnson, Todd R.

2017-09-12

A system for shaping a beam comprises an emitter for emitting coherent electromagnetic radiation. Birefringent displacers are configured between the emitter and a target wherein the at least two birefringent displacers split the coherent electromagnetic radiation into a plurality of coherent parallel beams of electromagnetic radiation thereby producing a shaped wave front of the coherent parallel beams of electromagnetic radiation.

SU-E-T-467: Implementation of Monte Carlo Dose Calculation for a Multileaf Collimator Equipped Robotic Radiotherapy System

DOE Office of Scientific and Technical Information (OSTI.GOV)

Li, JS; Fan, J; Ma, C-M

Purpose: To improve the treatment efficiency and capabilities for full-body treatment, a robotic radiosurgery system has equipped with a multileaf collimator (MLC) to extend its accuracy and precision to radiation therapy. To model the MLC and include it in the Monte Carlo patient dose calculation is the goal of this work. Methods: The radiation source and the MLC were carefully modeled to consider the effects of the source size, collimator scattering, leaf transmission and leaf end shape. A source model was built based on the output factors, percentage depth dose curves and lateral dose profiles measured in a water phantom.more » MLC leaf shape, leaf end design and leaf tilt for minimizing the interleaf leakage and their effects on beam fluence and energy spectrum were all considered in the calculation. Transmission/leakage was added to the fluence based on the transmission factors of the leaf and the leaf end. The transmitted photon energy was tuned to consider the beam hardening effects. The calculated results with the Monte Carlo implementation was compared with measurements in homogeneous water phantom and inhomogeneous phantoms with slab lung or bone material for 4 square fields and 9 irregularly shaped fields. Results: The calculated output factors are compared with the measured ones and the difference is within 1% for different field sizes. The calculated dose distributions in the phantoms show good agreement with measurements using diode detector and films. The dose difference is within 2% inside the field and the distance to agreement is within 2mm in the penumbra region. The gamma passing rate is more than 95% with 2%/2mm criteria for all the test cases. Conclusion: Implementation of Monte Carlo dose calculation for a MLC equipped robotic radiosurgery system is completed successfully. The accuracy of Monte Carlo dose calculation with MLC is clinically acceptable. This work was supported by Accuray Inc.« less

N-body simulations with a cosmic vector for dark energy

NASA Astrophysics Data System (ADS)

Carlesi, Edoardo; Knebe, Alexander; Yepes, Gustavo; Gottlöber, Stefan; Jiménez, Jose Beltrán.; Maroto, Antonio L.

2012-07-01

We present the results of a series of cosmological N-body simulations of a vector dark energy (VDE) model, performed using a suitably modified version of the publicly available GADGET-2 code. The set-ups of our simulations were calibrated pursuing a twofold aim: (1) to analyse the large-scale distribution of massive objects and (2) to determine the properties of halo structure in this different framework. We observe that structure formation is enhanced in VDE, since the mass function at high redshift is boosted up to a factor of 10 with respect to Λ cold dark matter (ΛCDM), possibly alleviating tensions with the observations of massive clusters at high redshifts and early reionization epoch. Significant differences can also be found for the value of the growth factor, which in VDE shows a completely different behaviour, and in the distribution of voids, which in this cosmology are on average smaller and less abundant. We further studied the structure of dark matter haloes more massive than 5 × 1013 h-1 M⊙, finding that no substantial difference emerges when comparing spin parameter, shape, triaxiality and profiles of structures evolved under different cosmological pictures. Nevertheless, minor differences can be found in the concentration-mass relation and the two-point correlation function, both showing different amplitudes and steeper slopes. Using an additional series of simulations of a ΛCDM scenario with the same ? and σ8 used in the VDE cosmology, we have been able to establish whether the modifications induced in the new cosmological picture were due to the particular nature of the dynamical dark energy or a straightforward consequence of the cosmological parameters. On large scales, the dynamical effects of the cosmic vector field can be seen in the peculiar evolution of the cluster number density function with redshift, in the shape of the mass function, in the distribution of voids and on the characteristic form of the growth index γ(z). On smaller scales, internal properties of haloes are almost unaffected by the change of cosmology, since no statistical difference can be observed in the characteristics of halo profiles, spin parameters, shapes and triaxialities. Only halo masses and concentrations show a substantial increase, which can, however, be attributed to the change in the cosmological parameters.

The role of hillslope topography on shallow landslides activation and basin saturation propensity

NASA Astrophysics Data System (ADS)

Lanni, C.; Pretto, I.; Rigon, R.

2009-12-01

Shallow Landslides are one of the most important causes of loss of human life and socio-economic damage related to the hydro-geological risk issues. In the past years a big number of researches have developed tools to assess for the stability condition of hillslopes at the basin-scale. Montgomery and Dietrich (1994), for instance, with their own SHALSTAB model, give a simple way to evaluate the safety factor of mountain hillslopes, coupling the infinite slope stability model with a very simple steady-state hydrological model based on the work by O'Loughlin (1986) and which has similarities to TOPOG (Beven and Kirkby, 1979). The state of art gives the possibility to evaluate the transient nature of the generated pore-pressure fields within soil-thickness during and after the rainfalls. A valuable tool to fulfill this purpose may be the GEOtop model (Rigon et al., 2006) born to solve the 3-dimensional form of Richards’ equation. The present work, which was held using GEOtop model, investigates the stability conditions and the water table level of nine characteristic hillslope types when steady-state conditions are reached. The artificial simple basins are created combining three different curvature's profile (straight, concave and convex) and three different plan shapes (parallel, convergent and divergent) (fig.1). In the analysis the hillslope soil thickness is imposed constant, while the bedrock is considered impermeable. Different intensity rainfalls are simulated. The results show that in the case of the lowest intensity rainfall, basins with convex shape present higher percentage of saturated area than concave and straight ones. Also, convergent hillslopes generally produce a higher percentage of saturated area than the other plan shapes. Moreover, in the case of higher intensity rainfalls, the concave profile curvature seems to be the first order controller on the saturation process. Regarding the stability conditions, convergent hillslopes generally presents a lower mean safety factor than parallel and divergent ones. Furthermore, concave hillslopes presents higher instability propensity, so that, as it is in the real word, concave hillslope tends to become convex because of the natural erosive process. Lastly, the obtained results are compared with the output given by the application of the SHALSTAB model considering the same setup used in the GEOtop numerical simulations.

Real-time feedback control of the plasma density profile on ASDEX Upgrade

NASA Astrophysics Data System (ADS)

Mlynek, A.; Reich, M.; Giannone, L.; Treutterer, W.; Behler, K.; Blank, H.; Buhler, A.; Cole, R.; Eixenberger, H.; Fischer, R.; Lohs, A.; Lüddecke, K.; Merkel, R.; Neu, G.; Ryter, F.; Zasche, D.; ASDEX Upgrade Team

2011-04-01

The spatial distribution of density in a fusion experiment is of significant importance as it enters in numerous analyses and contributes to the fusion performance. The reconstruction of the density profile is therefore commonly done in offline data analysis. In this paper, we present an algorithm which allows for density profile reconstruction from the data of the submillimetre interferometer and the magnetic equilibrium in real-time. We compare the obtained results to the profiles yielded by a numerically more complex offline algorithm. Furthermore, we present recent ASDEX Upgrade experiments in which we used the real-time density profile for active feedback control of the shape of the density profile.

Spectral Line-Shape Model to Replace the Voigt Profile in Spectroscopic Databases

NASA Astrophysics Data System (ADS)

Lisak, Daniel; Ngo, Ngoc Hoa; Tran, Ha; Hartmann, Jean-Michel

2014-06-01

The standard description of molecular line shapes in spectral databases and radiative transfer codes is based on the Voigt profile. It is well known that its simplified assumptions of absorber free motion and independence of collisional parameters from absorber velocity lead to systematic errors in analysis of experimental spectra, and retrieval of gas concentration. We demonstrate1,2 that the partially correlated quadratic speed-dependent hardcollision profile3. (pCqSDHCP) is a good candidate to replace the Voigt profile in the next generations of spectroscopic databases. This profile takes into account the following physical effects: the Doppler broadening, the pressure broadening and shifting of the line, the velocity-changing collisions, the speed-dependence of pressure broadening and shifting, and correlations between velocity- and phase/state-changing collisions. The speed-dependence of pressure broadening and shifting is incorporated into the pCqSDNGP in the so-called quadratic approximation. The velocity-changing collisions lead to the Dicke narrowing effect; however in many cases correlations between velocityand phase/state-changing collisions may lead to effective reduction of observed Dicke narrowing. The hard-collision model of velocity-changing collisions is also known as the Nelkin-Ghatak model or Rautian model. Applicability of the pCqSDHCP for different molecular systems was tested on calculated and experimental spectra of such molecules as H2, O2, CO2, H2O in a wide span of pressures. For all considered systems, pCqSDHCP is able to describe molecular spectra at least an order of magnitude better than the Voigt profile with all fitted parameters being linear with pressure. In the most cases pCqSDHCP can reproduce the reference spectra down to 0.2% or better, which fulfills the requirements of the most demanding remote-sensing applications. An important advantage of pCqSDHCP is that a fast algorithm for its computation was developedab4,5 and allows for its calculation only a few times slower than the standard Voigt profile. Moreover, the pCqSDHCP reduces to many simpler models commonly used in experimental spectra analysis simply by setting some parameters to zero, and it can be easily extended to incorporate the line-mixing effect in the first-order approximation. The idea of using pCqSDHCP as a standard profile to go beyond the Voigt profile for description of H2O line shapes was recently supported by the IUPAC task group6 which also recommended to call this profile with fast computation algorithm the HTP profile (for Hartmann-Tran).

Building CX peanut-shaped disk galaxy profiles. The relative importance of the 3D families of periodic orbits bifurcating at the vertical 2:1 resonance

NASA Astrophysics Data System (ADS)

Patsis, P. A.; Harsoula, M.

2018-05-01

Context. We present and discuss the orbital content of a rather unusual rotating barred galaxy model, in which the three-dimensional (3D) family, bifurcating from x1 at the 2:1 vertical resonance with the known "frown-smile" side-on morphology, is unstable. Aims: Our goal is to study the differences that occur in the phase space structure at the vertical 2:1 resonance region in this case, with respect to the known, well studied, standard case, in which the families with the frown-smile profiles are stable and support an X-shaped morphology. Methods: The potential used in the study originates in a frozen snapshot of an N-body simulation in which a fast bar has evolved. We follow the evolution of the vertical stability of the central family of periodic orbits as a function of the energy (Jacobi constant) and we investigate the phase space content by means of spaces of section. Results: The two bifurcating families at the vertical 2:1 resonance region of the new model change their stability with respect to that of most studied analytic potentials. The structure in the side-on view that is directly supported by the trapping of quasi-periodic orbits around 3D stable periodic orbits has now an infinity symbol (i.e. ∞-type) profile. However, the available sticky orbits can reinforce other types of side-on morphologies as well. Conclusions: In the new model, the dynamical mechanism of trapping quasi-periodic orbits around the 3D stable periodic orbits that build the peanut, supports the ∞-type profile. The same mechanism in the standard case supports the X shape with the frown-smile orbits. Nevertheless, in both cases (i.e. in the new and in the standard model) a combination of 3D quasi-periodic orbits around the stable x1 family with sticky orbits can support a profile reminiscent of the shape of the orbits of the 3D unstable family existing in each model.

Simulation of amide I' band profiles of trans polyproline based on an excitonic coupling model

NASA Astrophysics Data System (ADS)

Measey, Thomas; Schweitzer-Stenner, Reinhard

2005-06-01

We measured the amide I' band profile of the IR, isotropic Raman, anisotropic Raman, and Vibrational Circular Dichroism spectrum of poly- L-proline in D 2O. The band shapes were modeled by using an algorithm that exploits the delocalized character of the excited vibrational states [R. Schweitzer-Stenner, J. Phys. Chem. B. 108 (2004) 16965]. The band shapes could be quantitatively reproduced by invoking the polyproline II or 3 1-helix conformation for all peptide residues. This corroborates the notion that the combined use of the above spectroscopies is an ideal tool to discriminate different conformations associated with the so-called random coil state of peptides.

The effects of shockwave profile shape and shock obliquity on spallation in Cu and Ta: kinetic and stress-state effects on damage evolution(u)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gray, George T

2010-12-14

Widespread research over the past five decades has provided a wealth of experimental data and insight concerning shock hardening and the spallation response of materials subjected to square-topped shock-wave loading profiles. Less quantitative data have been gathered on the effect of direct, in-contact, high explosive (HE)-driven Taylor wave (or triangular-wave) loading profile shock loading on the shock hardening, damage evolution, or spallation response of materials. Explosive loading induces an impulse dubbed a 'Taylor Wave'. This is a significantly different loading history than that achieved by a square-topped impulse in terms of both the pulse duration at a fixed peak pressure,more » and a different unloading strain rate from the peak Hugoniot state achieved. The goal of this research is to quantify the influence of shockwave obliquity on the spallation response of copper and tantalum by subjecting plates of each material to HE-driven sweeping detonation-wave loading and quantify both the wave propagation and the post-mortem damage evolution. This talk will summarize our current understanding of damage evolution during sweeping detonation-wave spallation loading in Cu and Ta and show comparisons to modeling simulations. The spallation responses of Cu and Ta are both shown to be critically dependent on the shockwave profile and the stress-state of the shock. Based on variations in the specifics of the shock drive (pulse shape, peak stress, shock obliquity) and sample geometry in Cu and Ta, 'spall strength' varies by over a factor of two and the details of the mechanisms of the damage evolution is seen to vary. Simplistic models of spallation, such as P{sub min} based on 1-D square-top shock data lack the physics to capture the influence of kinetics on damage evolution such as that operative during sweeping detonation loading. Such considerations are important for the development of predictive models of damage evolution and spallation in metals and alloys.« less

Modular Design Features of a Peptide Amphiphile Micelle Vaccine Platform and Their Impact on an Immune Response

NASA Astrophysics Data System (ADS)

Barrett, John Christopher

Inducing a strong and specific immune response is the hallmark of a successful vaccine. Nanoparticles have emerged as promising vaccine delivery devices to discover and elicit immune responses. Modular platforms are attractive for their engineerability and broad potential applications. Fine-tuning a nanoparticle vaccine to create an immune response with specific antibody and other cellular responses is influenced by many factors such as shape, size and composition. Peptide amphiphile micelles are a unique biomaterials platform that can function as a modular vaccine delivery system, enabling control over many of these important factors. Peptide amphiphiles (PAs) consist of a hydrophilic peptide antigen conjugated to a hydrophobic lipid tail. The PAs then self-assemble into micelles, with the micelle characteristics determined by the chemical composition of the PA and micelle preparation methods. PA micelles contain a large design space, so it is important to have a basic understanding of how each design feature can affect the platform's interaction with the immune system. In this dissertation, the structure, composition, and biodistribution properties of PA micelles are evaluated for their ability to impact an immune response against a Group A Streptococcus B cell antigen (J8). Through structural design and physical characterization, micelles are shown to self-assemble into either short rod-like or long cylindrical shapes. Analyzing these shape effects on the immune response showed that cylindrical micelles induced higher antibody titers than rod-like micelles, providing evidence that the cylindrical micelle shape is important to induce immune responses and a possible mechanism of action. Shape was also seen to impact the activation profile of dendritic cells, B cells and T cells. Assembly into cylindrical micelles also stabilizes the secondary structure of peptide antigens, which may impact the immune response raised. In composition, the hydrophobic/hydrophilic interface of PA micelles enabled the precise entrapment of amphiphilic adjuvants which were found to not alter micelle formation or shape. These heterogeneous micelles significantly enhanced murine antibody responses when compared to animals vaccinated with non-adjuvanted micelles or soluble J8 peptide supplemented with a classical adjuvant. PAs were also shown to traffic more efficiently to the lymph node than free peptide. Characterization of these design features and their impact on an immune response provides a valuable foundation of knowledge to apply when expanding the peptide amphiphile micelle platform to other vaccine applications.

Interpretation of scrape-off layer profile evolution and first-wall ion flux statistics on JET using a stochastic framework based on fillamentary motion

NASA Astrophysics Data System (ADS)

Walkden, N. R.; Wynn, A.; Militello, F.; Lipschultz, B.; Matthews, G.; Guillemaut, C.; Harrison, J.; Moulton, D.; Contributors, JET

2017-08-01

This paper presents the use of a novel modelling technique based around intermittent transport due to filament motion, to interpret experimental profile and fluctuation data in the scrape-off layer (SOL) of JET during the onset and evolution of a density profile shoulder. A baseline case is established, prior to shoulder formation, and the stochastic model is shown to be capable of simultaneously matching the time averaged profile measurement as well as the PDF shape and autocorrelation function from the ion-saturation current time series at the outer wall. Aspects of the stochastic model are then varied with the aim of producing a profile shoulder with statistical measurements consistent with experiment. This is achieved through a strong localised reduction in the density sink acting on the filaments within the model. The required reduction of the density sink occurs over a highly localised region with the timescale of the density sink increased by a factor of 25. This alone is found to be insufficient to model the expansion and flattening of the shoulder region as the density increases, which requires additional changes within the stochastic model. An example is found which includes both a reduction in the density sink and filament acceleration and provides a consistent match to the experimental data as the shoulder expands, though the uniqueness of this solution can not be guaranteed. Within the context of the stochastic model, this implies that the localised reduction in the density sink can trigger shoulder formation, but additional physics is required to explain the subsequent evolution of the profile.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cegla, H. M.; Watson, C. A.; Oshagh, M.

Observations of the Rossiter–McLaughlin (RM) effect provide information on star–planet alignments, which can inform planetary migration and evolution theories. Here, we go beyond the classical RM modeling and explore the impact of a convective blueshift that varies across the stellar disk and non-Gaussian stellar photospheric profiles. We simulated an aligned hot Jupiter with a four-day orbit about a Sun-like star and injected center-to-limb velocity (and profile shape) variations based on radiative 3D magnetohydrodynamic simulations of solar surface convection. The residuals between our modeling and classical RM modeling were dependent on the intrinsic profile width and v sin i; the amplitudemore » of the residuals increased with increasing v sin i and with decreasing intrinsic profile width. For slowly rotating stars the center-to-limb convective variation dominated the residuals (with amplitudes of 10 s of cm s{sup −1} to ∼1 m s{sup −1}); however, for faster rotating stars the dominant residual signature was due a non-Gaussian intrinsic profile (with amplitudes from 0.5 to 9 m s{sup −1}). When the impact factor was 0, neglecting to account for the convective center-to-limb variation led to an uncertainty in the obliquity of ∼10°–20°, even though the true v sin i was known. Additionally, neglecting to properly model an asymmetric intrinsic profile had a greater impact for more rapidly rotating stars (e.g., v sin i = 6 km s{sup −1}) and caused systematic errors on the order of ∼20° in the measured obliquities. Hence, neglecting the impact of stellar surface convection may bias star–planet alignment measurements and consequently theories on planetary migration and evolution.« less

A Total Ozone Dependent Ozone Profile Climatology Based on Ozone-Sondes and Aura MLS Data

NASA Astrophysics Data System (ADS)

Labow, G. J.; McPeters, R. D.; Ziemke, J. R.

2014-12-01

A new total ozone-based ozone profile climatology has been created for use in satellite and/or ground based ozone retrievals. This climatology was formed by combining data from the Microwave Limb Sounder (MLS) with data from balloon sondes and binned by zone and total ozone. Because profile shape varies with total column ozone, this climatology better captures the ozone variations than the previously used seasonal climatologies, especially near the tropopause. This is significantly different than ozone climatologies used in the past as there is no time component. The MLS instrument on Aura has excellent latitude coverage and measures ozone profiles daily from the upper troposphere to the lower mesosphere at ~3.5 km resolution. Almost a million individual MLS ozone measurements are merged with data from over 55,000 ozonesondes which are then binned as a function of total ozone. The climatology consists of average ozone profiles as a function of total ozone for six 30 degree latitude bands covering altitudes from 0-75 km (in Z* pressure altitude coordinates). This new climatology better represents the profile shape as a function of total ozone than previous climatologies and shows some remarkable and somewhat unexpected correlations between total ozone and ozone in the lower altitudes, particularly in the lower and middle troposphere. These data can also be used to infer biases and errors in either the MLS retrievals or ozone sondes.

LORES: Low resolution shape program for the calculation of small angle scattering profiles for biological macromolecules in solution

NASA Astrophysics Data System (ADS)

Zhou, J.; Deyhim, A.; Krueger, S.; Gregurick, S. K.

2005-08-01

A program for determining the low resolution shape of biological macromolecules, based on the optimization of a small angle neutron scattering profile to experimental data, is presented. This program, termed LORES, relies on a Monte Carlo optimization procedure and will allow for multiple scattering length densities of complex structures. It is therefore more versatile than utilizing a form factor approach to produce low resolution structural models. LORES is easy to compile and use, and allows for structural modeling of biological samples in real time. To illustrate the effectiveness and versatility of the program, we present four specific biological examples, Apoferritin (shell model), Ribonuclease S (ellipsoidal model), a 10-mer dsDNA (duplex helix) and a construct of a 10-mer DNA/PNA duplex helix (heterogeneous structure). These examples are taken from protein and nucleic acid SANS studies, of both large and small scale structures. We find, in general, that our program will accurately reproduce the geometric shape of a given macromolecule, when compared with the known crystallographic structures. We also present results to illustrate the lower limit of the experimental resolution which the LORES program is capable of modeling. Program summaryTitle of program:LORES Catalogue identifier: ADVC Program summary URL:http://cpc.cs.qub.ac.uk/summaries/ADVC Program obtainable from: CPC Program Library, Queen's University of Belfast, N. Ireland Computer:SGI Origin200, SGI Octane, SGI Linux, Intel Pentium PC Operating systems:UNIX64 6.5 and LINUX 2.4.7 Programming language used:C Memory required to execute with typical data:8 MB No. of lines in distributed program, including test data, etc.:2270 No. of bytes in distributed program, including test data, etc.:13 302 Distribution format:tar.gz External subprograms used:The entire code must be linked with the MATH library

Composition of Dietary Fat Source Shapes Gut Microbiota Architecture and Alters Host Inflammatory Mediators in Mouse Adipose Tissue

PubMed Central

Huang, Edmond; Leone, Vanessa; Devkota, Suzanne; Wang, Yunwei; Brady, Matthew; Chang, Eugene

2013-01-01

Background Growing evidence shows that dietary factors can dramatically alter the gut microbiome in ways that contribute to metabolic disturbance and progression of obesity. In this regard, mesenteric adipose tissue has been implicated in mediating these processes through the elaboration of pro-inflammatory adipokines. In this study, we examined the relationship of these events by determining the effects of dietary fat content and source on gut microbiota, as well as the effects on adipokine profiles of mesenteric and peripheral adipocytes. Methods Adult male C57Bl/6 mice were fed milk fat-, lard-(SFA sources), or safflower oil (PUFA)- based high fat diets for four weeks. Body mass and food consumption were measured. Stool 16S rRNA was isolated and analyzed via T-RFLP as well as variable V3-4 sequence tags via next gen sequencing. Mesenteric and gonadal adipose samples were analyzed for both lipogenic and inflammatory mediators via qRT-PCR. Results High-fat feedings caused more weight gain with concomitant increases in caloric consumption relative to low-fat diets. Additionally, each of the high fat diets induced dramatic and specific 16S rRNA phylogenic profiles that were associated with different inflammatory and lipogenic mediator profile of mesenteric and gonadal fat depots. Conclusions Our findings support the notion that dietary fat composition can both reshape the gut microbiota as well as alter host adipose tissue inflammatory/lipogenic profiles. They also demonstrate the interdependency of dietary fat source, commensal gut microbiota, and inflammatory profile of mesenteric fat that can collectively impact the host metabolic state. PMID:23639897

Self-absorption characteristics of measured laser-induced plasma line shapes

NASA Astrophysics Data System (ADS)

Parigger, C. G.; Surmick, D. M.; Gautam, G.

2017-02-01

The determination of electron density and temperature is reported from line-of-sight measurements of laser-induced plasma. Experiments are conducted in standard ambient temperature and pressure air and in a cell containing ultra-high-pure hydrogen slightly above atmospheric pressure. Spectra of the hydrogen Balmer series lines can be measured in laboratory air due to residual moisture following optical breakdown generated with 13 to 14 nanosecond, pulsed Nd:YAG laser radiation. Comparisons with spectra obtained in hydrogen gas yields Abel-inverted line shape appearances that indicate occurrence of self-absorption. The electron density and temperature distributions along the line of sight show near-spherical rings, expanding at or near the speed of sound in the hydrogen gas experiments. The temperatures in the hydrogen studies are obtained using Balmer series alpha, beta, gamma profiles. Over and above the application of empirical formulae to derive the electron density from hydrogen alpha width and shift, and from hydrogen beta width and peak-separation, so-called escape factors and the use of a doubling mirror are discussed.

New medium used in the differentiation of human pluripotent stem cells to retinal cells is comparable to fetal human eye tissue.

PubMed

Wang, Xiaobing; Xiong, Kai; Lin, Cong; Lv, Lei; Chen, Jing; Xu, Chongchong; Wang, Songtao; Gu, Dandan; Zheng, Hua; Yu, Hurong; Li, Yan; Xiao, Honglei; Zhou, Guomin

2015-06-01

Human pluripotent stem cells (hPSCs) have the potential to differentiate along the retinal lineage. However, most induction systems are dependent on multiple small molecular compounds such as Dkk-1, Lefty-A, and retinoic acid. In the present study, we efficiently differentiated hPSCs into retinal cells using a retinal differentiation medium (RDM) without the use of small molecular compounds. This novel differentiation system recapitulates retinal morphogenesis in humans, i.e. hPSCs gradually differentiate into optic vesicle-shaped spheres, followed by optic cup-shaped spheres and, lastly, retinal progenitor cells. Furthermore, at different stages, hPSC-derived retinal cells mirror the transcription factor expression profiles seen in their counterparts during human embryogenesis. Most importantly, hinge epithelium was found between the hPSC-derived neural retina (NR) and retinal pigment epithelium (RPE). These data suggest that our culture system provides a new method for generating hPSC-derived retinal cells that, for the first time, might be used in human transplantation. Copyright © 2015 Elsevier Ltd. All rights reserved.

Coronary disease risk curve of serum creatinine is linear in Turkish men, U-shaped in women.

PubMed

Onat, Altan; Can, Günay; Ademoğlu, Evin; Çelik, Etem; Karagöz, Ahmet; Örnek, Ender

2013-01-01

The highest levels of glomerular filtration rate are associated with increased coronary heart disease (CHD) risk, an issue we investigated in separate sexes in a population prone to metabolic syndrome. In total, 1948 participants of the Turkish Adult Risk Factor study with available creatinine determinations were studied at a mean 3.4 years' follow-up. Using quartiles of creatinine, risk in Cox models of incident CHD or the likelihood of combined prevalent and incident CHD was assessed. Women in the lowest creatinine quartile demonstrated the lowest risk profile across diverse variables, except showing low high-density lipoprotein cholesterol and average apolipoprotein A-I and lipoprotein (a) concentrations implicating impaired atheroprotective properties. Whereas serum creatinine in men was not significantly associated with 6 proinflammatory variables comprised in linear regression analysis, apolipoprotein A-I and lipoprotein (a) were significant positive covariates in women, the latter tending to negative association in women without metabolic syndrome. In men, the highest (>1.10 mg/dL), compared with the lowest, creatinine quartile significantly predicted CHD risk, at 1.85-fold relative risks, after adjustment for established risk factors. The risk curve in women was U-shaped, the top and bottom quartiles tending to display higher risk (odds ratio, 1.28 [95% confidence interval, 0.91-1.80]) compared with the 2 intermediate quartiles. Increasing serum creatinine values are associated strongly and independently with CHD risk in men but not in women in whom the risk curve is U-shaped. The phenomenon of low creatinine levels underlies some hitherto unexplained relevant observations, and low measurements may be attributed to inassayability secondary to involvement in autoimmune activation.

Tree species distribution in temperate forests is more influenced by soil than by climate.

PubMed

Walthert, Lorenz; Meier, Eliane Seraina

2017-11-01

Knowledge of the ecological requirements determining tree species distributions is a precondition for sustainable forest management. At present, the abiotic requirements and the relative importance of the different abiotic factors are still unclear for many temperate tree species. We therefore investigated the relative importance of climatic and edaphic factors for the abundance of 12 temperate tree species along environmental gradients. Our investigations are based on data from 1,075 forest stands across Switzerland including the cold-induced tree line of all studied species and the drought-induced range boundaries of several species. Four climatic and four edaphic predictors represented the important growth factors temperature, water supply, nutrient availability, and soil aeration. The climatic predictors were derived from the meteorological network of MeteoSwiss, and the edaphic predictors were available from soil profiles. Species cover abundances were recorded in field surveys. The explanatory power of the predictors was assessed by variation partitioning analyses with generalized linear models. For six of the 12 species, edaphic predictors were more important than climatic predictors in shaping species distribution. Over all species, abundances depended mainly on nutrient availability, followed by temperature, water supply, and soil aeration. The often co-occurring species responded similar to these growth factors. Drought turned out to be a determinant of the lower range boundary for some species. We conclude that over all 12 studied tree species, soil properties were more important than climate variables in shaping tree species distribution. The inclusion of appropriate soil variables in species distribution models allowed to better explain species' ecological niches. Moreover, our study revealed that the ecological requirements of tree species assessed in local field studies and in experiments are valid at larger scales across Switzerland.

Note: A contraction channel design for planar shock wave enhancement

NASA Astrophysics Data System (ADS)

Zhan, Dongwen; Li, Zhufei; Yang, Jianting; Zhu, Yujian; Yang, Jiming

2018-05-01

A two-dimensional contraction channel with a theoretically designed concave-oblique-convex wall profile is proposed to obtain a smooth planar-to-planar shock transition with shock intensity amplification that can easily overcome the limitations of a conventional shock tube. The concave segment of the wall profile, which is carefully determined based on shock dynamics theory, transforms the shock shape from an initial plane into a cylindrical arc. Then the level of shock enhancement is mainly contributed by the cylindrical shock convergence within the following oblique segment, after which the cylindrical shock is again "bent" back into a planar shape through the third section of the shock dynamically designed convex segment. A typical example is presented with a combination of experimental and numerical methods, where the shape of transmitted shock is almost planar and the post-shock flow has no obvious reflected waves. A quantitative investigation shows that the difference between the designed and experimental transmitted shock intensities is merely 1.4%. Thanks to its advantage that the wall profile design is insensitive to initial shock strength variations and high-temperature gas effects, this method exhibits attractive potential as an efficient approach to a certain, controllable, extreme condition of a strong shock wave with relatively uniform flow behind.

Model-based segmentation of abdominal aortic aneurysms in CTA images

NASA Astrophysics Data System (ADS)

de Bruijne, Marleen; van Ginneken, Bram; Niessen, Wiro J.; Loog, Marco; Viergever, Max A.

2003-05-01

Segmentation of thrombus in abdominal aortic aneurysms is complicated by regions of low boundary contrast and by the presence of many neighboring structures in close proximity to the aneurysm wall. We present an automated method that is similar to the well known Active Shape Models (ASM), combining a three-dimensional shape model with a one-dimensional boundary appearance model. Our contribution is twofold: we developed a non-parametric appearance modeling scheme that effectively deals with a highly varying background, and we propose a way of generalizing models of curvilinear structures from small training sets. In contrast with the conventional ASM approach, the new appearance model trains on both true and false examples of boundary profiles. The probability that a given image profile belongs to the boundary is obtained using k nearest neighbor (kNN) probability density estimation. The performance of this scheme is compared to that of original ASMs, which minimize the Mahalanobis distance to the average true profile in the training set. The generalizability of the shape model is improved by modeling the objects axis deformation independent of its cross-sectional deformation. A leave-one-out experiment was performed on 23 datasets. Segmentation using the kNN appearance model significantly outperformed the original ASM scheme; average volume errors were 5.9% and 46% respectively.

Exploring Local Level Factors Shaping the Implementation of a Blended Learning Module for Information and Geospatial Literacy in Ontario

ERIC Educational Resources Information Center

Vine, Michelle M.; Chiappetta-Swanson, Catherine; Maclachlan, John; Brodeur, Jason J.; Bagg, Julianne

2016-01-01

The objectives of this research study were to examine local level factors shaping the implementation of a blended pedagogical approach for geospatial- and information-literacy, and to understand implementer satisfaction. As such, we addressed the following research questions: What local-level factors shape the implementation of the blended…

Trends in stratospheric ozone profiles using functional mixed models

NASA Astrophysics Data System (ADS)

Park, A.; Guillas, S.; Petropavlovskikh, I.

2013-11-01

This paper is devoted to the modeling of altitude-dependent patterns of ozone variations over time. Umkehr ozone profiles (quarter of Umkehr layer) from 1978 to 2011 are investigated at two locations: Boulder (USA) and Arosa (Switzerland). The study consists of two statistical stages. First we approximate ozone profiles employing an appropriate basis. To capture primary modes of ozone variations without losing essential information, a functional principal component analysis is performed. It penalizes roughness of the function and smooths excessive variations in the shape of the ozone profiles. As a result, data-driven basis functions (empirical basis functions) are obtained. The coefficients (principal component scores) corresponding to the empirical basis functions represent dominant temporal evolution in the shape of ozone profiles. We use those time series coefficients in the second statistical step to reveal the important sources of the patterns and variations in the profiles. We estimate the effects of covariates - month, year (trend), quasi-biennial oscillation, the solar cycle, the Arctic oscillation, the El Niño/Southern Oscillation cycle and the Eliassen-Palm flux - on the principal component scores of ozone profiles using additive mixed effects models. The effects are represented as smooth functions and the smooth functions are estimated by penalized regression splines. We also impose a heteroscedastic error structure that reflects the observed seasonality in the errors. The more complex error structure enables us to provide more accurate estimates of influences and trends, together with enhanced uncertainty quantification. Also, we are able to capture fine variations in the time evolution of the profiles, such as the semi-annual oscillation. We conclude by showing the trends by altitude over Boulder and Arosa, as well as for total column ozone. There are great variations in the trends across altitudes, which highlights the benefits of modeling ozone profiles.

Predicting kinetic nanocrystal shapes through multi-scale theory and simulation: Polyvinylpyrrolidone-mediated growth of Ag nanocrystals

NASA Astrophysics Data System (ADS)

Balankura, Tonnam; Qi, Xin; Zhou, Ya; Fichthorn, Kristen A.

2016-10-01

In the shape-controlled synthesis of colloidal Ag nanocrystals, structure-directing agents, particularly polyvinylpyrrolidone (PVP), are known to be a key additive in making nanostructures with well-defined shapes. Although many Ag nanocrystals have been successfully synthesized using PVP, the mechanism by which PVP actuates shape control remains elusive. Here, we present a multi-scale theoretical framework for kinetic Wulff shape predictions that accounts for the chemical environment, which we used to probe the kinetic influence of the adsorbed PVP film. Within this framework, we use umbrella-sampling molecular dynamics simulations to calculate the potential of mean force and diffusion coefficient profiles of Ag atom deposition onto Ag(100) and Ag(111) in ethylene glycol solution with surface-adsorbed PVP. We use these profiles to calculate the mean-first passage times and implement extensive Brownian dynamics simulations, which allows the kinetic effects to be quantitatively evaluated. Our results show that PVP films can regulate the flux of Ag atoms to be greater towards Ag(111) than Ag(100). PVP's preferential binding towards Ag(100) over Ag(111) gives PVP its flux-regulating capabilities through the lower free-energy barrier of Ag atoms to cross the lower-density PVP film on Ag(111) and enhanced Ag trapping by the extended PVP film on Ag(111). Under kinetic control, {100}-faceted nanocrystals will be formed when the Ag flux is greater towards Ag(111). The predicted kinetic Wulff shapes are in agreement with the analogous experimental system.

Generalization of Solovev’s approach to finding equilibrium solutions for axisymmetric plasmas with flow

NASA Astrophysics Data System (ADS)

M, S. CHU; Yemin, HU; Wenfeng, GUO

2018-03-01

Solovev’s approach of finding equilibrium solutions was found to be extremely useful for generating a library of linear-superposable equilibria for the purpose of shaping studies. This set of solutions was subsequently expanded to include the vacuum solutions of Zheng, Wootton and Solano, resulting in a set of functions {SOLOVEV_ZWS} that were usually used for all toroidally symmetric plasmas, commonly recognized as being able to accommodate any desired plasma shapes (complete-shaping capability). The possibility of extending the Solovev approach to toroidal equilibria with a general plasma flow is examined theoretically. We found that the only meaningful extension is to plasmas with a pure toroidal rotation and with a constant Mach number. We also show that the simplification ansatz made to the current profiles, which was the basis of the Solovev approach, should be applied more systematically to include an internal boundary condition at the magnetic axis; resulting in a modified and more useful set {SOLOVEV_ZWSm}. Explicit expressions of functions in this set are given for equilibria with a quasi-constant current density profile, with a toroidal flow at a constant Mach number and with specific heat capacity 1. The properties of {SOLOVEV_ZWSm} are studied analytically. Numerical examples of achievable equilibria are demonstrated. Although the shaping capability of the set {SOLOVE_ZWSm} is quite extensive, it nevertheless still does not have complete shaping capability, particularly for plasmas with negative curvature points on the plasma boundary such as the doublets or indented bean shaped tokamaks.

Beam shaping as an enabler for new applications

NASA Astrophysics Data System (ADS)

Guertler, Yvonne; Kahmann, Max; Havrilla, David

2017-02-01

For many years, laser beam shaping has enabled users to achieve optimized process results as well as manage challenging applications. The latest advancements in industrial lasers and processing optics have taken this a step further as users are able to adapt the beam shape to meet specific application requirements in a very flexible way. TRUMPF has developed a wide range of experience in creating beam profiles at the work piece for optimized material processing. This technology is based on the physical model of wave optics and can be used with ultra short pulse lasers as well as multi-kW cw lasers. Basically, the beam shape can be adapted in all three dimensions in space, which allows maximum flexibility. Besides adaption of intensity profile, even multi-spot geometries can be produced. This approach is very cost efficient, because a standard laser source and (in the case of cw lasers) a standard fiber can be used without any special modifications. Based on this innovative beam shaping technology, TRUMPF has developed new and optimized processes. Two of the most recent application developments using these techniques are cutting glass and synthetic sapphire with ultra-short pulse lasers and enhanced brazing of hot dip zinc coated steel for automotive applications. Both developments lead to more efficient and flexible production processes, enabled by laser technology and open the door to new opportunities. They also indicate the potential of beam shaping techniques since they can be applied to both single-mode laser sources (TOP Cleave) and multi-mode laser sources (brazing).

Chip-carrier thermal barrier and its impact on lateral thermal lens profile and beam parameter product in high power broad area lasers

NASA Astrophysics Data System (ADS)

Rieprich, J.; Winterfeldt, M.; Kernke, R.; Tomm, J. W.; Crump, P.

2018-03-01

High power broad area diode lasers with high optical power density in a small focus spot are in strong commercial demand. For this purpose, the beam quality, quantified via the beam parameter product (BPP), has to be improved. Previous studies have shown that the BPP is strongly affected by current-induced heating and the associated thermal lens formed within the laser stripe. However, the chip structure and module-assembly related factors that regulate the size and the shape of the thermal lens are not well known. An experimental infrared thermographic technique is used to quantify the thermal lens profile in diode lasers operating at an emission wavelength of 910 nm, and the results are compared with finite element method simulations. The analysis indicates that the measured thermal profiles can best be explained when a thermal barrier is introduced between the chip and the carrier, which is shown to have a substantial impact on the BPP and the thermal resistance. Comparable results are observed in further measurements of samples from multiple vendors, and the barrier is only observed for junction-down (p-down) mounting, consistent with the barrier being associated with the GaAs-metal transition.

The Wonder Years: A Profile of Madhav Chavan

ERIC Educational Resources Information Center

Mukerji, Shalini

2017-01-01

An idea took shape in the slums of Mumbai in the early nineties and went on to become a peoples' movement to address the problem of providing quality education for all of India's children. This piece profiles Dr. Madhav Chavan, the man who provided the dynamic vision for and creative leadership of that mission/movement. Dr. Chavan combined the…

Evaluation of the 3-GeV proton beam profile at the spallation target of the JSNS

NASA Astrophysics Data System (ADS)

Meigo, Shin-ichiro; Noda, Fumiaki; Ishikura, Syuichi; Futakawa, Masatoshi; Sakamoto, Shinichi; Ikeda, Yujiro

2006-06-01

At JSNS, 3-GeV protons beam is delivered from rapid cycling synchrotron (RCS) to the spallation neutron target. In order to reduce the damage of pitting on the target container, the peak current density should be kept as small as possible. In this study, the beam profile at spallation neutron target is evaluated. The phase-space distribution, including the space-charge effect, is calculated with SIMPSONS code. The beam profile on the target is obtained with the transfer matrix from exit of RCS to the target. As for injection to RCS, two methods of correlated and anti-correlated painting are considered. By using anti-correlated painting for injection of beam at RCS, it is found the shape of beam becomes flatter than the distribution by using correlated painting. As other aspect for the study of target, in order to carry out target performance test especially for the study of pitting issue, it is better to have the beam profile variety from the beginning of facility. The adjustable range for the beam profile at the beginning is also studied. Although the beam shape is narrow and the duty is very low, the strong enough peak density is achievable equivalent as 1 MW.

Fundamental Parameters Line Profile Fitting in Laboratory Diffractometers

PubMed Central

Cheary, R. W.; Coelho, A. A.; Cline, J. P.

2004-01-01

The fundamental parameters approach to line profile fitting uses physically based models to generate the line profile shapes. Fundamental parameters profile fitting (FPPF) has been used to synthesize and fit data from both parallel beam and divergent beam diffractometers. The refined parameters are determined by the diffractometer configuration. In a divergent beam diffractometer these include the angular aperture of the divergence slit, the width and axial length of the receiving slit, the angular apertures of the axial Soller slits, the length and projected width of the x-ray source, the absorption coefficient and axial length of the sample. In a parallel beam system the principal parameters are the angular aperture of the equatorial analyser/Soller slits and the angular apertures of the axial Soller slits. The presence of a monochromator in the beam path is normally accommodated by modifying the wavelength spectrum and/or by changing one or more of the axial divergence parameters. Flat analyzer crystals have been incorporated into FPPF as a Lorentzian shaped angular acceptance function. One of the intrinsic benefits of the fundamental parameters approach is its adaptability any laboratory diffractometer. Good fits can normally be obtained over the whole 20 range without refinement using the known properties of the diffractometer, such as the slit sizes and diffractometer radius, and emission profile. PMID:27366594

Onto the stability analysis of hyperbolic secant-shaped Bose-Einstein condensate

NASA Astrophysics Data System (ADS)

Sabari, S.; Murali, R.

2018-05-01

We analyze the stability of the hyperbolic secant-shaped attractive Bose-Einstein condensate in the absence of external trapping potential. The appropriate theoretical model for the system is described by the nonlinear mean-field Gross-Pitaevskii equation with time varying two-body interaction effects. Using the variational method, the stability of the system is analyzed under the influence of time varying two-body interactions. Further we confirm that the stability of the attractive condensate increases by considering the hyperbolic secant-shape profile instead of Gaussian shape. The analytical results are compared with the numerical simulation by employing the split-step Crank-Nicholson method.

Design Models for Shaping of a Tooth Profile of External Fine-Module Ratchet Teeth

NASA Astrophysics Data System (ADS)

Sharkov, O. V.; Koryagin, S. I.; Velikanov, N. L.

2016-04-01

Simulation of the shaping for the fine-module external ratchet teeth at which the contacting surfaces are formed by the straight segments is considered in this paper. The design schemes for shaping of the proposed ratchet teeth by a shaper cutter and a rack are obtained. It is defined that the maximum length of the straight segment of the front edge ratchet teeth will be formed at shaping by a rack cutter. The effect of a module, a gradient angle and a radius of blank circles on the length of the straight segment of the front edge ratchet teeth is investigated.

Acoustic contrast control in an arc-shaped area using a linear loudspeaker array.

PubMed

Zhao, Sipei; Qiu, Xiaojun; Burnett, Ian

2015-02-01

This paper proposes a method of creating acoustic contrast control in an arc-shaped area using a linear loudspeaker array. The boundary of the arc-shaped area is treated as the envelope of the tangent lines that can be formed by manipulating the phase profile of the loudspeakers in the array. When compared with the existing acoustic contrast control method, the proposed method is able to generate sound field inside an arc-shaped area and achieve a trade-off between acoustic uniformity and acoustic contrast. The acoustic contrast created by the proposed method increases while the acoustic uniformity decreases with frequency.

Factors influencing body image in individuals after a first heart attack.

PubMed

Zarek, Aleksandra; Barański, Jarosław

Experiencing a heart attack can change the attitude of patients towards their corporeality. Body image may significantly influence the recovery of patients, their adherence to medical recommendations, and adopting a healthy lifestyle. The aim of this study was to analyze the relationship between body image and personality characteristics, as well as sociodemographic, physical and medical factors in patients after a first myocardial infarction. The study comprised 160 patients after a first heart attack (80 women and 80 men) aged 34–65 years (mean = 53.44; SD = 6.40). Body image was measured with the Body Image Questionnaire, and personality was analyzed according to the Adjective Check List. The level of body satisfaction was shaped by two dimensions of personality (Sociability, Weakness and inhibition) and by respondents’ gender. In respondents’ personality profile, lower body satisfaction was associated with elevated Weakness and inhibition and with lowered Sociability. Women were less satisfied with their bodies than men. The significance attributed to one’s own body was shaped by two dimensions of personality (Expansiveness, Weakness and inhibition) and by respondents’ age. Patients with a higher degree of Expansiveness, a lower degree of Weakness and inhibition and more advanced in age gave greater priority to corporeality. Improving body image in persons after a first heart attack should be combined with the development of personality abilities important for self-efficacy and social competency.

Adaptive electron beam shaping using a photoemission gun and spatial light modulator

DOE Office of Scientific and Technical Information (OSTI.GOV)

Maxson, Jared; Lee, Hyeri; Bartnik, Adam C.

The need for precisely defined beam shapes in photoelectron sources has been well established. In this paper, we use a spatial light modulator and simple shaping algorithm to create arbitrary, detailed transverse laser shapes with high fidelity. We transmit this shaped laser to the photocathode of a high voltage dc gun. Using beam currents where space charge is negligible, and using an imaging solenoid and fluorescent viewscreen, we show that the resultant beam shape preserves these detailed features with similar fidelity. Next, instead of transmitting a shaped laser profile, we use an active feedback on the unshaped electron beam imagemore » to create equally accurate and detailed shapes. We demonstrate that this electron beam feedback has the added advantage of correcting for electron optical aberrations, yielding shapes without skew. The method may serve to provide precisely defined electron beams for low current target experiments, space-charge dominated beam commissioning, as well as for online adaptive correction of photocathode quantum efficiency degradation.« less

Adaptive electron beam shaping using a photoemission gun and spatial light modulator

NASA Astrophysics Data System (ADS)

Maxson, Jared; Lee, Hyeri; Bartnik, Adam C.; Kiefer, Jacob; Bazarov, Ivan

2015-02-01

The need for precisely defined beam shapes in photoelectron sources has been well established. In this paper, we use a spatial light modulator and simple shaping algorithm to create arbitrary, detailed transverse laser shapes with high fidelity. We transmit this shaped laser to the photocathode of a high voltage dc gun. Using beam currents where space charge is negligible, and using an imaging solenoid and fluorescent viewscreen, we show that the resultant beam shape preserves these detailed features with similar fidelity. Next, instead of transmitting a shaped laser profile, we use an active feedback on the unshaped electron beam image to create equally accurate and detailed shapes. We demonstrate that this electron beam feedback has the added advantage of correcting for electron optical aberrations, yielding shapes without skew. The method may serve to provide precisely defined electron beams for low current target experiments, space-charge dominated beam commissioning, as well as for online adaptive correction of photocathode quantum efficiency degradation.

Adaptive electron beam shaping using a photoemission gun and spatial light modulator

DOE PAGES

Maxson, Jared; Lee, Hyeri; Bartnik, Adam C.; ...

2015-02-01

The need for precisely defined beam shapes in photoelectron sources has been well established. In this paper, we use a spatial light modulator and simple shaping algorithm to create arbitrary, detailed transverse laser shapes with high fidelity. We transmit this shaped laser to the photocathode of a high voltage dc gun. Using beam currents where space charge is negligible, and using an imaging solenoid and fluorescent viewscreen, we show that the resultant beam shape preserves these detailed features with similar fidelity. Next, instead of transmitting a shaped laser profile, we use an active feedback on the unshaped electron beam imagemore » to create equally accurate and detailed shapes. We demonstrate that this electron beam feedback has the added advantage of correcting for electron optical aberrations, yielding shapes without skew. The method may serve to provide precisely defined electron beams for low current target experiments, space-charge dominated beam commissioning, as well as for online adaptive correction of photocathode quantum efficiency degradation.« less

A Three-Dimensional Coupled Internal/External Simulation of a Film-Cooled Turbine Vane

NASA Technical Reports Server (NTRS)

Heidmann, James D.; Rigby, David L.; Ameri, Ali A.

1999-01-01

A three-dimensional Navier-Stokes simulation has been performed for a realistic film-cooled turbine vane using the LeRC-HT code. The simulation includes the flow regions inside the coolant plena and film cooling holes in addition to the external flow. The vane is the subject of an upcoming NASA Glenn Research Center experiment and has both circular cross-section and shaped film cooling holes. This complex geometry is modeled using a multi-block grid which accurately discretizes the actual vane geometry including shaped holes. The simulation matches operating conditions for the planned experiment and assumes periodicity in the spanwise direction on the scale of one pitch of the film cooling hole pattern. Two computations were performed for different isothermal wall temperatures, allowing independent determination of heat transfer coefficients and film effectiveness values. The results indicate separate localized regions of high heat transfer coefficient values, while the shaped holes provide a reduction in heat flux through both parameters. Hole exit data indicate rather simple skewed profiles for the round holes, but complex profiles for the shaped holes with mass fluxes skewed strongly toward their leading edges.

Age-dependent Fourier model of the shape of the isolated ex vivo human crystalline lens.

PubMed

Urs, Raksha; Ho, Arthur; Manns, Fabrice; Parel, Jean-Marie

2010-06-01

To develop an age-dependent mathematical model of the zero-order shape of the isolated ex vivo human crystalline lens, using one mathematical function, that can be subsequently used to facilitate the development of other models for specific purposes such as optical modeling and analytical and numerical modeling of the lens. Profiles of whole isolated human lenses (n=30) aged 20-69, were measured from shadow-photogrammetric images. The profiles were fit to a 10th-order Fourier series consisting of cosine functions in polar-co-ordinate system that included terms for tilt and decentration. The profiles were corrected using these terms and processed in two ways. In the first, each lens was fit to a 10th-order Fourier series to obtain thickness and diameter, while in the second, all lenses were simultaneously fit to a Fourier series equation that explicitly include linear terms for age to develop an age-dependent mathematical model for the whole lens shape. Thickness and diameter obtained from Fourier series fits exhibited high correlation with manual measurements made from shadow-photogrammetric images. The root-mean-squared-error of the age-dependent fit was 205 microm. The age-dependent equations provide a reliable lens model for ages 20-60 years. The contour of the whole human crystalline lens can be modeled with a Fourier series. Shape obtained from the age-dependent model described in this paper can be used to facilitate the development of other models for specific purposes such as optical modeling and analytical and numerical modeling of the lens. Copyright (c) 2010 Elsevier Ltd. All rights reserved.

Slope gradient and shape effects on soil profiles in the northern mountainous forests of Iran

NASA Astrophysics Data System (ADS)

Fazlollahi Mohammadi, M.; Jalali, S. G. H.; Kooch, Y.; Said-Pullicino, D.

2016-12-01

In order to evaluate the variability of the soil profiles at two shapes (concave and convex) and five positions (summit, shoulder, back slope, footslope and toeslope) of a slope, a study of a virgin area was made in a Beech stand of mountain forests, northern Iran. Across the slope positions, the soil profiles demonstrated significant changes due to topography for two shape slopes. The solum depth of the convex slope was higher than the concave one in all five positions, and it decreased from the summit to shoulder and increased from the mid to lower slope positions for both convex and concave slopes. The thin solum at the upper positions and concave slope demonstrated that pedogenetic development is least at upper slope positions and concave slope where leaching and biomass productivity are less than at lower slopes and concave slope. A large decrease in the thickness of O and A horizons from the summit to back slope was noted for both concave and convex slopes, but it increased from back slope toward down slope for both of them. The average thickness of B horizons increased from summit to down slopes in the case of the concave slope, but in the case of convex slope it decreased from summit to shoulder and afterwards it increased to the down slope. The thicknesses of the different horizons varied in part in the different positions and shape slopes because they had different plant species cover and soil features, which were related to topography.

Voids in cosmological simulations over cosmic time

NASA Astrophysics Data System (ADS)

Wojtak, Radosław; Powell, Devon; Abel, Tom

2016-06-01

We study evolution of voids in cosmological simulations using a new method for tracing voids over cosmic time. The method is based on tracking watershed basins (contiguous regions around density minima) of well-developed voids at low redshift, on a regular grid of density field. It enables us to construct a robust and continuous mapping between voids at different redshifts, from initial conditions to the present time. We discuss how the new approach eliminates strong spurious effects of numerical origin when voids' evolution is traced by matching voids between successive snapshots (by analogy to halo merger trees). We apply the new method to a cosmological simulation of a standard Λ-cold-dark-matter cosmological model and study evolution of basic properties of typical voids (with effective radii 6 h-1 Mpc < Rv < 20 h-1 Mpc at redshift z = 0) such as volumes, shapes, matter density distributions and relative alignments. The final voids at low redshifts appear to retain a significant part of the configuration acquired in initial conditions. Shapes of voids evolve in a collective way which barely modifies the overall distribution of the axial ratios. The evolution appears to have a weak impact on mutual alignments of voids implying that the present state is in large part set up by the primordial density field. We present evolution of dark matter density profiles computed on isodensity surfaces which comply with the actual shapes of voids. Unlike spherical density profiles, this approach enables us to demonstrate development of theoretically predicted bucket-like shape of the final density profiles indicating a wide flat core and a sharp transition to high-density void walls.

Shape, zonal winds and gravitational field of Jupiter: a fully self-consistent, multi-layered model

NASA Astrophysics Data System (ADS)

Schubert, Gerald; Kong, Dali; Zhang, Keke

2016-10-01

We construct a three-dimensional, finite-element, fully self-consistent, multi-layered,non-spheroidal model of Jupiter consisting of an inner core, a metallic electrically conducting dynamo region and an outer molecular electrically insulating envelope. We assume that the Jovian zonal winds are on cylinders parallel to the rotation axis but, due to the effect of magnetic braking, are confined within the outer molecular envelope. Two related calculations are carried out. The first provides an accurate description of the shape and internal density profile of Jupiter; the effect of rotational distortion is not treated as a small perturbation on a spherically symmetric state. This calculation determines the density, size and shape of the inner core, the irregular shape of the 1-bar pressure level, and the internal structure of Jupiter; the full effect of rotational distortion, without the influence of the zonal winds, is accounted for. Our multi-layered model is able to produce the known mass, the known equatorial and polar radii, and the known zonal gravitational coefficient J2 of Jupiter within their error bars; it also yields the coefficients J4 and J6 within about 5% accuracy, and the core equatorial radius 0.09RJ containing 3.73 Earth masses.The second calculation determines the variation of the gravitational field caused solely by the effect of the zonal winds on the rotationally distorted non-spheroidal Jupiter. Four different cases, ranging from a deep wind profile to a very shallow profile, are considered and implications for accurate interpretation of the zonal gravitational coefficients expected from the Juno mission are discussed.

Actuation of a robotic fish caudal fin for low reaction torque

NASA Astrophysics Data System (ADS)

Yun, Dongwon; Kim, Kyung-Soo; Kim, Soohyun; Kyung, Jinho; Lee, Sunghee

2011-07-01

In this paper, a novel caudal fin for actuating a robotic fish is presented. The proposed caudal fin waves in a vertical direction with a specific spatial shape, which is determined by a so-called shape factor. For a specific shape factor, a traveling wave with a vertical phase difference is formed on a caudal fin during fin motion. It will be shown by the analysis that the maximum reaction torque at the joint of a caudal fin varies depending on the shape factors. Compared with a conventional plate type caudal fin, the proposed fin with a shape factor of 2π can eliminate the reaction torque perfectly, while keeping the propulsion force unchanged. The benefits of the proposed fin will be demonstrated by experiments.

In situ 3D nanoprinting of free-form coupling elements for hybrid photonic integration

NASA Astrophysics Data System (ADS)

Dietrich, P.-I.; Blaicher, M.; Reuter, I.; Billah, M.; Hoose, T.; Hofmann, A.; Caer, C.; Dangel, R.; Offrein, B.; Troppenz, U.; Moehrle, M.; Freude, W.; Koos, C.

2018-04-01

Hybrid photonic integration combines complementary advantages of different material platforms, offering superior performance and flexibility compared with monolithic approaches. This applies in particular to multi-chip concepts, where components can be individually optimized and tested. The assembly of such systems, however, requires expensive high-precision alignment and adaptation of optical mode profiles. We show that these challenges can be overcome by in situ printing of facet-attached beam-shaping elements. Our approach allows precise adaptation of vastly dissimilar mode profiles and permits alignment tolerances compatible with cost-efficient passive assembly techniques. We demonstrate a selection of beam-shaping elements at chip and fibre facets, achieving coupling efficiencies of up to 88% between edge-emitting lasers and single-mode fibres. We also realize printed free-form mirrors that simultaneously adapt beam shape and propagation direction, and we explore multi-lens systems for beam expansion. The concept paves the way to automated assembly of photonic multi-chip systems with unprecedented performance and versatility.

Asymmetric crack propagation near waterfall cliff and its influence on the waterfall lip shape

NASA Astrophysics Data System (ADS)

Vastola, G.

2011-11-01

By means of Finite Element Method (FEM) calculations and fatigue fracture mechanics analysis, we show that crack propagation in bedrocks close to the waterfall cliff is preferential towards the cliff face rather than upstream the river. Based on this effect, we derive the corresponding expression for the velocity of recession vr of the waterfall lip, and find that vr has a quadratic dependence on the hydrostatic pressure. Quantitatively, this erosion mechanism generates recession rates of the order of ~cm-dm/y, consistent with the recession rates of well-known waterfalls. We enclose our expression for vr into a growth model to investigate the time evolution of a waterfall lip subject to this erosional mechanism. Because of the dependence on hydrostatic pressure, the shape of the waterfall is influenced by the transverse profile of the river that generates the waterfall. If the river has a transverse concavity, the waterfall evolves a curved shape. Evolution for the case of meanders with asymmetric transverse profile is also given.

An axial temperature profile curvature criterion for the engineering of convex crystal growth interfaces in Bridgman systems

NASA Astrophysics Data System (ADS)

Peterson, Jeffrey H.; Derby, Jeffrey J.

2017-06-01

A unifying idea is presented for the engineering of convex melt-solid interface shapes in Bridgman crystal growth systems. Previous approaches to interface control are discussed with particular attention paid to the idea of a "booster" heater. Proceeding from the idea that a booster heater promotes a converging heat flux geometry and from the energy conservation equation, we show that a convex interface shape will naturally result when the interface is located in regions of the furnace where the axial thermal profile exhibits negative curvature, i.e., where d2 T / dz2 < 0 . This criterion is effective in explaining prior literature results on interface control and promising for the evaluation of new furnace designs. We posit that the negative curvature criterion may be applicable to the characterization of growth systems via temperature measurements in an empty furnace, providing insight about the potential for achieving a convex interface shape, without growing a crystal or conducting simulations.

Shape control of slack space reflectors using modulated solar pressure.

PubMed

Borggräfe, Andreas; Heiligers, Jeannette; Ceriotti, Matteo; McInnes, Colin R

2015-07-08

The static deflection profile of a large spin-stabilized space reflector because of solar radiation pressure acting on its surface is investigated. Such a spacecraft consists of a thin reflective circular film, which is deployed from a supporting hoop structure in an untensioned, slack manner. This paper investigates the use of a variable reflectivity distribution across the surface to control the solar pressure force and hence the deflected shape. In this first analysis, the film material is modelled as one-dimensional slack radial strings with no resistance to bending or transverse shear, which enables a semi-analytic derivation of the nominal deflection profile. An inverse method is then used to find the reflectivity distribution that generates a specific, for example, parabolic deflection shape of the strings. Applying these results to a parabolic reflector, short focal distances can be obtained when large slack lengths of the film are employed. The development of such optically controlled reflector films enables future key mission applications such as solar power collection, radio-frequency antennae and optical telescopes.

A model of transverse fuel injection applied to the computation of supersonic combustor flow

NASA Technical Reports Server (NTRS)

Rogers, R. C.

1979-01-01

A two-dimensional, nonreacting flow model of the aerodynamic interaction of a transverse hydrogen jet within a supersonic mainstream has been developed. The model assumes profile shapes of mass flux, pressure, flow angle, and hydrogen concentration and produces downstream profiles of the other flow parameters under the constraints of the integrated conservation equations. These profiles are used as starting conditions for an existing finite difference parabolic computer code for the turbulent supersonic combustion of hydrogen. Integrated mixing and flow profile results obtained from the computer code compare favorably with existing data for the supersonic combustion of hydrogen.

Micromachined single-level nonplanar polycrystalline SiGe thermal microemitters for infrared dynamic scene projection

NASA Astrophysics Data System (ADS)

Malyutenko, V. K.; Malyutenko, O. Yu.; Leonov, V.; Van Hoof, C.

2009-05-01

The technology for self-supported membraneless polycrystalline SiGe thermal microemitters, their design, and performance are presented. The 128-element arrays with a fill factor of 88% and a 2.5-μm-thick resonant cavity have been grown by low-pressure chemical vapor deposition and fabricated using surface micromachining technology. The 200-nm-thick 60×60 μm2 emitting pixels enforced with a U-shape profile pattern demonstrate a thermal time constant of 2-7 ms and an apparent temperature of 700 K in the 3-5 and 8-12 μm atmospheric transparency windows. The application of the devices to the infrared dynamic scene simulation and their benefit over conventional planar membrane-supported emitters are discussed.

Mass estimating techniques for earth-to-orbit transports with various configuration factors and technologies applied

NASA Technical Reports Server (NTRS)

Klich, P. J.; Macconochie, I. O.

1979-01-01

A study of an array of advanced earth-to-orbit space transportation systems with a focus on mass properties and technology requirements is presented. Methods of estimating weights of these vehicles differ from those used for commercial and military aircraft; the new techniques emphasizing winged horizontal and vertical takeoff advanced systems are described utilizing the space shuttle subsystem data base for the weight estimating equations. The weight equations require information on mission profile, the structural materials, the thermal protection system, and the ascent propulsion system, allowing for the type of construction and various propellant tank shapes. The overall system weights are calculated using this information and incorporated into the Systems Engineering Mass Properties Computer Program.

A real-time intercepting beam-profile monitor for a medical cyclotron

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hendriks, C.; Uittenbosch, T.; Cameron, D.

2013-11-15

There is a lack of real-time continuous beam-diagnostic tools for medical cyclotrons due to high power deposition during proton irradiation. To overcome this limitation, we have developed a profile monitor that is capable of providing continuous feedback about beam shape and current in real time while it is inserted in the beam path. This enables users to optimize the beam profile and observe fluctuations in the beam over time with periodic insertion of the monitor.

Spectral analysis of aeromagnetic profiles for depth estimation principles, software, and practical application

USGS Publications Warehouse

Sadek, H.S.; Rashad, S.M.; Blank, H.R.

1984-01-01

If proper account is taken of the constraints of the method, it is capable of providing depth estimates to within an accuracy of about 10 percent under suitable circumstances. The estimates are unaffected by source magnetization and are relatively insensitive to assumptions as to source shape or distribution. The validity of the method is demonstrated by analyses of synthetic profiles and profiles recorded over Harrat Rahat, Saudi Arabia, and Diyur, Egypt, where source depths have been proved by drilling.

Effects of inlet distortion on gas turbine combustion chamber exit temperature profiles

NASA Astrophysics Data System (ADS)

Maqsood, Omar Shahzada

Damage to a nozzle guide vane or blade, caused by non-uniform temperature distributions at the combustion chamber exit, is deleterious to turbine performance and can lead to expensive and time consuming overhaul and repair. A test rig was designed and constructed for the Allison 250-C20B combustion chamber to investigate the effects of inlet air distortion on the combustion chamber's exit temperature fields. The rig made use of the engine's diffuser tubes, combustion case, combustion liner, and first stage nozzle guide vane shield. Rig operating conditions simulated engine cruise conditions, matching the quasi-non-dimensional Mach number, equivalence ratio and Sauter mean diameter. The combustion chamber was tested with an even distribution of inlet air and a 4% difference in airflow at either side. An even distribution of inlet air to the combustion chamber did not create a uniform temperature profile and varying the inlet distribution of air exacerbated the profile's non-uniformity. The design of the combustion liner promoted the formation of an oval-shaped toroidal vortex inside the chamber, creating localized hot and cool sections separated by 90° that appeared in the exhaust. Uneven inlet air distributions skewed the oval vortex, increasing the temperature of the hot section nearest the side with the most mass flow rate and decreasing the temperature of the hot section on the opposite side. Keywords: Allison 250, Combustion, Dual-Entry, Exit Temperature Profile, Gas Turbine, Pattern Factor, Reverse Flow.

Application of the Hartmann–Tran profile to precise experimental data sets of 12C 2H 2

DOE PAGES

Forthomme, D.; Cich, M. J.; Twagirayezu, S.; ...

2015-06-25

Self- and nitrogen-broadened line shape data for the P e(11) line of the ν₁ + ν₃ band of acetylene, recorded using a frequency comb-stabilized laser spectrometer, have been analyzed using the Hartmann–Tran profile (HTP) line shape model in a multispectrum fitting. In total, the data included measurements recorded at temperatures between 125 K and 296 K and at pressures between 4 and 760 Torr. New, sub-Doppler, frequency comb-referenced measurements of the positions of multiple underlying hot band lines have also been made. These underlying lines significantly affect the P e(11) line profile at temperatures above 240 K and poorly knownmore » frequencies previously introduced errors into the line shape analyses. Thus, the behavior of the HTP model was compared to the quadratic speed dependent Voigt profile (QSDVP) expressed in the frequency and time domains. A parameter uncertainty analysis was carried out using a Monte Carlo method based on the estimated pressure, transmittance and frequency measurement errors. From the analyses, the P e(11) line strength was estimated to be 1.2014(50) × 10 -20 in cm.molecules⁻¹ units at 296 K with the standard deviation in parenthesis. For analyzing these data, we found that a reduced form of the HTP, equivalent to the QSDVP, was most appropriate because the additional parameters included in the full HTP were not well determined. As a supplement to this work, expressions for analytic derivatives and a lineshape fitting code written in Matlab for the HTP are available.« less

Application of the Hartmann-Tran profile to precise experimental data sets of 12C2H2

NASA Astrophysics Data System (ADS)

Forthomme, D.; Cich, M. J.; Twagirayezu, S.; Hall, G. E.; Sears, T. J.

2015-11-01

Self- and nitrogen-broadened line shape data for the Pe(11) line of the ν1 +ν3 band of acetylene, recorded using a frequency comb-stabilized laser spectrometer, have been analyzed using the Hartmann-Tran profile (HTP) line shape model in a multispectrum fitting. In total, the data included measurements recorded at temperatures between 125 K and 296 K and at pressures between 4 and 760 Torr. New, sub-Doppler, frequency comb-referenced measurements of the positions of multiple underlying hot band lines have also been made. These underlying lines significantly affect the Pe(11) line profile at temperatures above 240 K and poorly known frequencies previously introduced errors into the line shape analyses. The behavior of the HTP model was compared to the quadratic speed dependent Voigt profile (QSDVP) expressed in the frequency and time domains. A parameter uncertainty analysis was carried out using a Monte Carlo method based on the estimated pressure, transmittance and frequency measurement errors. From the analyses, the Pe(11) line strength was estimated to be 1.2014(50) ×10-20 in cmmolecule-1 units at 296 K with the standard deviation in parenthesis. For analyzing these data, we found that a reduced form of the HTP, equivalent to the QSDVP, was most appropriate because the additional parameters included in the full HTP were not well determined. As a supplement to this work, expressions for analytic derivatives and a lineshape fitting code written in Matlab for the HTP are available.

Phillips-Tikhonov regularization with a priori information for neutron emission tomographic reconstruction on Joint European Torus

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bielecki, J.; Scholz, M.; Drozdowicz, K.

A method of tomographic reconstruction of the neutron emissivity in the poloidal cross section of the Joint European Torus (JET, Culham, UK) tokamak was developed. Due to very limited data set (two projection angles, 19 lines of sight only) provided by the neutron emission profile monitor (KN3 neutron camera), the reconstruction is an ill-posed inverse problem. The aim of this work consists in making a contribution to the development of reliable plasma tomography reconstruction methods that could be routinely used at JET tokamak. The proposed method is based on Phillips-Tikhonov regularization and incorporates a priori knowledge of the shape ofmore » normalized neutron emissivity profile. For the purpose of the optimal selection of the regularization parameters, the shape of normalized neutron emissivity profile is approximated by the shape of normalized electron density profile measured by LIDAR or high resolution Thomson scattering JET diagnostics. In contrast with some previously developed methods of ill-posed plasma tomography reconstruction problem, the developed algorithms do not include any post-processing of the obtained solution and the physical constrains on the solution are imposed during the regularization process. The accuracy of the method is at first evaluated by several tests with synthetic data based on various plasma neutron emissivity models (phantoms). Then, the method is applied to the neutron emissivity reconstruction for JET D plasma discharge #85100. It is demonstrated that this method shows good performance and reliability and it can be routinely used for plasma neutron emissivity reconstruction on JET.« less

Oscillatory shear response of moisture barrier coatings containing clay of different shape factor.

PubMed

Kugge, C; Vanderhoek, N; Bousfield, D W

2011-06-01

Oscillatory shear rheology of barrier coatings based on dispersed styrene-butadiene latex and clay of various shape factors or aspect ratio has been explored. Barrier performance of these coatings when applied to paperboard has been assessed in terms of water vapour transmission rates and the results related to shape factor, dewatering and critical strain. It has been shown that a system based on clay with high shape factor gives a lower critical strain, dewatering and water vapour transmission rate compared with clays of lower shape factor. The dissipated energy, as calculated from an amplitude sweep, indicated no attractive interaction between clay and latex implying a critical strain that appears to be solely dependent on the shape factor at a constant volume fraction. Particle size distribution was shown to have no effect on the critical strain while coatings of high elasticity exhibited high yield strains as expected. The loss modulus demonstrated strain hardening before the elastic to viscous transition. The loss modulus peak was identified by a maximum strain which was significantly lower for a coating based on clay with a high shape factor. The characteristic elastic time was found to vary between 0.6 and 1.3s. The zero shear viscosity of barrier dispersion coatings were estimated from the characteristic elastic time and the characteristic modulus to be of the order of 25-100 Pa s. Copyright © 2011 Elsevier Inc. All rights reserved.

Quality of the log-geometric distribution extrapolation for smaller undiscovered oil and gas pool size

USGS Publications Warehouse

Chenglin, L.; Charpentier, R.R.

2010-01-01

The U.S. Geological Survey procedure for the estimation of the general form of the parent distribution requires that the parameters of the log-geometric distribution be calculated and analyzed for the sensitivity of these parameters to different conditions. In this study, we derive the shape factor of a log-geometric distribution from the ratio of frequencies between adjacent bins. The shape factor has a log straight-line relationship with the ratio of frequencies. Additionally, the calculation equations of a ratio of the mean size to the lower size-class boundary are deduced. For a specific log-geometric distribution, we find that the ratio of the mean size to the lower size-class boundary is the same. We apply our analysis to simulations based on oil and gas pool distributions from four petroleum systems of Alberta, Canada and four generated distributions. Each petroleum system in Alberta has a different shape factor. Generally, the shape factors in the four petroleum systems stabilize with the increase of discovered pool numbers. For a log-geometric distribution, the shape factor becomes stable when discovered pool numbers exceed 50 and the shape factor is influenced by the exploration efficiency when the exploration efficiency is less than 1. The simulation results show that calculated shape factors increase with those of the parent distributions, and undiscovered oil and gas resources estimated through the log-geometric distribution extrapolation are smaller than the actual values. ?? 2010 International Association for Mathematical Geology.

Jet Mixing in Direct-Chill Casting of Aluminum: Crater Effects and its Consequence on Centerline Segregation

NASA Astrophysics Data System (ADS)

Wagstaff, Samuel R.; Allanore, Antoine

2017-08-01

Recent reports have demonstrated the possibility of mitigating macrosegregation during the Direct-Chill casting of rolling slab ingots using an impinging jet. Herein, an analytical model is presented to predict the shape of the crater formed due to the impact of the jet on the slurry region. The model takes into account alloy composition, physical dimension, and casting speed on the distribution of forces and crater shape. The calculated shape of the crater profile is used to explain the centerline depletion in the impingement region previously reported.

Seasonal variability of aerosol vertical profiles over east US and west Europe: GEOS-Chem/APM simulation and comparison with CALIPSO observations

NASA Astrophysics Data System (ADS)

Ma, Xiaoyan; Yu, Fangqun

2014-04-01

In this study, we employed 5 years (2007-2011) of the CALIPSO level-3 monthly aerosol extinction product to compare with the GEOS-Chem/APM simulations for the same time period over two major industrial regions (east US and west Europe). The objective is to understand which aerosol types or species significantly determine the vertical profiles by comparing the seasonal variability between the simulations and observations. Our study shows that the model successfully produces the magnitude of aerosol extinction, profile shape, and their seasonal variability observed by CALIPSO over both east US (EUS) and west Europe (WEU). The extinctions below 1 km make up 44-79% to the total, from either the model simulations or satellite retrievals, with larger percentages in winter seasons (62-79%) and smaller percentages in summer seasons (44-57%) associated with the strength of vertical transport. The shape of the vertical profiles has, therefore, a distinct seasonal variability, with a more like quasi-exponential shape in DJF (December, January, and February) and SON (September, October, and November) than in MAM (March, April, and May) and JJA (June, July, and August), which have been discerned from both measurements and simulations. Analysis of modeled aerosol species indicates that secondary particles (SP), containing sulfate, ammonia, nitrate, and secondary organic aerosols (SOAs), predominantly determine the total aerosol vertical profiles while black carbon (BC), primary organic carbon (OC), and sea salt (SS), only account for a small fraction and are also limited near the surface. Mineral dust (DS) contributes more to the total extinction over WEU than over EUS, particularly in MAM, a result of being adjacent to the North Africa desert. Secondary inorganic aerosol (SIA, i.e. sulfate, ammonia, and nitrate) contributes most of the total SP mass in DJF and SON while SOA is particularly important in MAM and JJA when the emissions from leafed plants are active. Our study also indicates that, compared to aerosol extinction, the number concentration of particles larger than 10 nm (CN10) exhibits a different seasonal variation and vertical profile, but Cloud Condensation Nuclei (CCN) concentration at supersaturation of 0.4% (CCN0.4) presents a consistent seasonal variation and similar vertical profile. Therefore, aerosol extinction could be a good indicator for CCN0.4 with regard to seasonal variations of vertical profiles.

Strain and Ge concentration determinations in SiGe/Si multiple quantum wells by transmission electron microscopy methods

NASA Astrophysics Data System (ADS)

Benedetti, A.; Norris, D. J.; Hetherington, C. J. D.; Cullis, A. G.; Robbins, D. J.; Wallis, D. J.

2003-04-01

SiGe/Si multiple quantum wells, nominally 4 nm thick, were grown by low pressure chemical vapor deposition and the Ge distribution within the wells was studied using a variety of transmission electron microscope-based techniques. Energy-dispersive x-ray spectroscopy and electron energy-loss imaging were used to directly measure the Ge compositional profile across the SiGe wells. In addition, the average Ge concentration was deduced indirectly from measurement of the strain-induced lattice displacements in high resolution images, obtained from the relative phase shift of the Si lattice planes on either side of a SiGe well. The results from both the direct and indirect measurement techniques were compared and found to be in good agreement with one another. The Ge profiles exhibited an asymmetric shape consistent with the occurrence of Ge segregation during growth. However, the amplitude of the asymmetry indicated that an additional factor, in particular gas dwell times within the reactor, also needed to be taken into account. Based upon this approach, a successful theoretical model of the growth process was derived.

Analytical treatment of the deformation behavior of EUVL masks during electrostatic chucking

NASA Astrophysics Data System (ADS)

Brandstetter, Gerd; Govindjee, Sanjay

2012-03-01

A new analytical approach is presented to predict mask deformation during electro-static chucking in next generation extreme-ultraviolet-lithography (EUVL). Given an arbitrary profile measurement of the mask and chuck non-flatness, this method has been developed as an alternative to time-consuming finite element simulations for overlay error correction algorithms. We consider the feature transfer of each harmonic component in the profile shapes via linear elasticity theory and demonstrate analytically how high spatial frequencies are filtered. The method is compared to presumably more accurate finite element simulations and has been tested successfully in an overlay error compensation experiment, where the residual error y-component could be reduced by a factor 2. As a side outcome, the formulation provides a tool to estimate the critical pin-size and -pitch such that the distortion on the mask front-side remains within given tolerances. We find for a numerical example that pin-pitches of less than 5 mm will result in a mask pattern-distortion of less than 1 nm if the chucking pressure is below 30 kPa.

Analytical treatment of the deformation behavior of extreme-ultraviolet-lithography masks during electrostatic chucking

NASA Astrophysics Data System (ADS)

Brandstetter, Gerd; Govindjee, Sanjay

2012-10-01

A new analytical approach is presented to predict mask deformation during electrostatic chucking in next-generation extreme-ultraviolet-lithography. Given an arbitrary profile measurement of the mask and chuck nonflatness, this method has been developed as an alternative to time-consuming finite element simulations for overlay error correction algorithms. We consider the feature transfer of each harmonic component in the profile shapes via linear elasticity theory and demonstrate analytically how high spatial frequencies are filtered. The method is compared to presumably more accurate finite element simulations and has been tested successfully in an overlay error compensation experiment, where the residual error y-component could be reduced by a factor of 2. As a side outcome, the formulation provides a tool to estimate the critical pin-size and -pitch such that the distortion on the mask front-side remains within given tolerances. We find for a numerical example that pin-pitches of less than 5 mm will result in a mask pattern distortion of less than 1 nm if the chucking pressure is below 30 kPa.

Elliptic Cylinder Airborne Sampling and Geostatistical Mass Balance Approach for Quantifying Local Greenhouse Gas Emissions.

PubMed

Tadić, Jovan M; Michalak, Anna M; Iraci, Laura; Ilić, Velibor; Biraud, Sébastien C; Feldman, Daniel R; Bui, Thaopaul; Johnson, Matthew S; Loewenstein, Max; Jeong, Seongeun; Fischer, Marc L; Yates, Emma L; Ryoo, Ju-Mee

2017-09-05

In this study, we explore observational, experimental, methodological, and practical aspects of the flux quantification of greenhouse gases from local point sources by using in situ airborne observations, and suggest a series of conceptual changes to improve flux estimates. We address the major sources of uncertainty reported in previous studies by modifying (1) the shape of the typical flight path, (2) the modeling of covariance and anisotropy, and (3) the type of interpolation tools used. We show that a cylindrical flight profile offers considerable advantages compared to traditional profiles collected as curtains, although this new approach brings with it the need for a more comprehensive subsequent analysis. The proposed flight pattern design does not require prior knowledge of wind direction and allows for the derivation of an ad hoc empirical correction factor to partially alleviate errors resulting from interpolation and measurement inaccuracies. The modified approach is applied to a use-case for quantifying CH 4 emission from an oil field south of San Ardo, CA, and compared to a bottom-up CH 4 emission estimate.

Constraining Viewing Geometries of Pulsars with Single-Peaked Gamma-ray Profiles Using a Multiwavelength Approach

NASA Technical Reports Server (NTRS)

Seyffert, A. S.; Venter, C.; Johnson, T. J.; Harding, A. K.

2012-01-01

Since the launch of the Large Area Telescope (LAT) on board the Fermi spacecraft in June 2008, the number of observed gamma-ray pulsars has increased dramatically. A large number of these are also observed at radio frequencies. Constraints on the viewing geometries of 5 of 6 gamma-ray pulsars exhibiting single-peaked gamma-ray profiles were derived using high-quality radio polarization data [1]. We obtain independent constraints on the viewing geometries of 6 by using a geometric emission code to model the Fermi LAT and radio light curves (LCs). We find fits for the magnetic inclination and observer angles by searching the solution space by eye. Our results are generally consistent with those previously obtained [1], although we do find small differences in some cases. We will indicate how the gamma-ray and radio pulse shapes as well as their relative phase lags lead to constraints in the solution space. Values for the flux correction factor (f(omega)) corresponding to the fits are also derived (with errors).

Shaping of Rack Cutter Original Profile for Fine-module Ratchet Teeth Cutting

NASA Astrophysics Data System (ADS)

Sharkov, O. V.; Koryagin, S. I.; Velikanov, N. L.

2018-05-01

The design models and the process of shaping the cutting edges of the rack cutter for cutting fine-module ratchet teeth are considered in the article. The use of fine-module ratchet teeth can reduce the noise and impact loads during operation of the freewheel mechanisms. Mathematical dependencies for calculating the coordinates determining the geometric position of the points of the front and back edges of the cutting profile of the rack cutter, the workpiece angle of rotation during cutting the ratchet teeth were obtained. When applying the developed method, the initial data are: the radii of the workpiece circumferences passing through the dedendum of the external and internal cut teeth; gradient angles of the front and back edges of the rail.

Use of pattern recognition and neural networks for non-metric sex diagnosis from lateral shape of calvarium: an innovative model for computer-aided diagnosis in forensic and physical anthropology.

PubMed

Cavalli, Fabio; Lusnig, Luca; Trentin, Edmondo

2017-05-01

Sex determination on skeletal remains is one of the most important diagnosis in forensic cases and in demographic studies on ancient populations. Our purpose is to realize an automatic operator-independent method to determine the sex from the bone shape and to test an intelligent, automatic pattern recognition system in an anthropological domain. Our multiple-classifier system is based exclusively on the morphological variants of a curve that represents the sagittal profile of the calvarium, modeled via artificial neural networks, and yields an accuracy higher than 80 %. The application of this system to other bone profiles is expected to further improve the sensibility of the methodology.

Carbon Dioxide Line Shapes for Atmospheric Remote Sensing

NASA Astrophysics Data System (ADS)

Predoi-Cross, Adriana; Ibrahim, Amr; Wismath, Alice; Teillet, Philippe M.; Devi, V. Malathy; Benner, D. Chris; Billinghurst, Brant

2010-02-01

We present a detailed spectroscopic study of carbon dioxide in support of atmospheric remote sensing. We have studied two weak absorption bands near the strong ν2 band that is used to derive atmospheric temperature profiles. We have analyzed our laboratory spectra recorded with the synchrotron and globar sources with spectral line profiles that reproduce the absorption features with high accuracy. The Q-branch transitions exhibited asymmetric line shape due to weak line-mixing. For these weak transitions, we have retrieved accurate experimental line strengths, self- and air-broadening, self- and air-induced shift coefficients and weak line mixing parameters. The experimental precision is sufficient to reveal inherent variations of the width and shift coefficients according to transition quantum numbers.

β-connectin studies by small-angle x-ray scattering and single-molecule force spectroscopy by atomic force microscopy

NASA Astrophysics Data System (ADS)

Marchetti, S.; Sbrana, F.; Toscano, A.; Fratini, E.; Carlà, M.; Vassalli, M.; Tiribilli, B.; Pacini, A.; Gambi, C. M. C.

2011-05-01

The three-dimensional structure and the mechanical properties of a β-connectin fragment from human cardiac muscle, belonging to the I band, from I27 to I34, were investigated by small-angle x-ray scattering (SAXS) and single-molecule force spectroscopy (SMFS). This molecule presents an entropic elasticity behavior, associated to globular domain unfolding, that has been widely studied in the last 10 years. In addition, atomic force microscopy based SMFS experiments suggest that this molecule has an additional elastic regime, for low forces, probably associated to tertiary structure remodeling. From a structural point of view, this behavior is a mark of the fact that the eight domains in the I27-I34 fragment are not independent and they organize in solution, assuming a well-defined three-dimensional structure. This hypothesis has been confirmed by SAXS scattering, both on a diluted and a concentrated sample. Two different models were used to fit the SAXS curves: one assuming a globular shape and one corresponding to an elongated conformation, both coupled with a Coulomb repulsion potential to take into account the protein-protein interaction. Due to the predominance of the structure factor, the effective shape of the protein in solution could not be clearly disclosed. By performing SMFS by atomic force microscopy, mechanical unfolding properties were investigated. Typical sawtooth profiles were obtained and the rupture force of each unfolding domain was estimated. By fitting a wormlike chain model to each peak of the sawtooth profile, the entropic elasticity of octamer was described.

Analysis of pressure head-flow loops of pulsatile rotodynamic blood pumps.

PubMed

Jahren, Silje E; Ochsner, Gregor; Shu, Fangjun; Amacher, Raffael; Antaki, James F; Vandenberghe, Stijn

2014-04-01

The clinical importance of pulsatility is a recurring topic of debate in mechanical circulatory support. Lack of pulsatility has been identified as a possible factor responsible for adverse events and has also demonstrated a role in myocardial perfusion and cardiac recovery. A commonly used method for restoring pulsatility with rotodynamic blood pumps (RBPs) is to modulate the speed profile, synchronized to the cardiac cycle. This introduces additional parameters that influence the (un)loading of the heart, including the timing (phase shift) between the native cardiac cycle and the pump pulses, and the amplitude of speed modulation. In this study, the impact of these parameters upon the heart-RBP interaction was examined in terms of the pressure head-flow (HQ) diagram. The measurements were conducted using a rotodynamic Deltastream DP2 pump in a validated hybrid mock circulation with baroreflex function. The pump was operated with a sinusoidal speed profile, synchronized to the native cardiac cycle. The simulated ventriculo-aortic cannulation showed that the level of (un)loading and the shape of the HQ loops strongly depend on the phase shift. The HQ loops displayed characteristic shapes depending on the phase shift. Increased contribution of native contraction (increased ventricular stroke work [WS ]) resulted in a broadening of the loops. It was found that the previously described linear relationship between WS and the area of the HQ loop for constant pump speeds becomes a family of linear relationships, whose slope depends on the phase shift. © 2013 Wiley Periodicals, Inc. and International Center for Artificial Organs and Transplantation.

Convergence to a pulsating travelling wave for an epidemic reaction-diffusion system with non-diffusive susceptible population.

PubMed

Ducrot, Arnaud; Giletti, Thomas

2014-09-01

In this work we study the asymptotic behaviour of the Kermack-McKendrick reaction-diffusion system in a periodic environment with non-diffusive susceptible population. This problem was proposed by Kallen et al. as a model for the spatial spread for epidemics, where it can be reasonable to assume that the susceptible population is motionless. For arbitrary dimensional space we prove that large classes of solutions of such a system have an asymptotic spreading speed in large time, and that the infected population has some pulse-like asymptotic shape. The analysis of the one-dimensional problem is more developed, as we are able to uncover a much more accurate description of the profile of solutions. Indeed, we will see that, for some initially compactly supported infected population, the profile of the solution converges to some pulsating travelling wave with minimal speed, that is to some entire solution moving at a constant positive speed and whose profile's shape is periodic in time.

Calculation of catalyst crust thickness from full elemental laser-induced breakdown spectroscopy images

NASA Astrophysics Data System (ADS)

Sorbier, L.; Trichard, F.; Moncayo, S.; Lienemann, C. P.; Motto-Ros, V.

2018-01-01

We propose a methodology to compute the crust thickness of an element in an egg-shell catalyst from a two-dimensional elemental map. The methodology handles two important catalyst shapes: infinite extrudates of arbitrary section and spheres. The methodology is validated with synthetic analytical profiles on simple shapes (cylinder and sphere). Its relative accuracy is shown close to few percent with a decrease inversely proportional to the square root of the number of sampled pixels. The crust thickness obtained by this method from quantitative Pd maps acquired by laser-induced breakdown spectroscopy are comparable with values obtained from electron-probe microanalysis profiles. Some discrepancies are found and are explained by the heterogeneity of the crust thickness within a grain. As a full map is more representative than a single profile, fast mapping and the methodology exposed in this paper are expected to become valuable tools for the development of new generations of egg-shell deposited catalysts.

Monitoring of Time-Dependent System Profiles by Multiplex Gas Chromatography with Maximum Entropy Demodulation

NASA Technical Reports Server (NTRS)

Becker, Joseph F.; Valentin, Jose

1996-01-01

The maximum entropy technique was successfully applied to the deconvolution of overlapped chromatographic peaks. An algorithm was written in which the chromatogram was represented as a vector of sample concentrations multiplied by a peak shape matrix. Simulation results demonstrated that there is a trade off between the detector noise and peak resolution in the sense that an increase of the noise level reduced the peak separation that could be recovered by the maximum entropy method. Real data originated from a sample storage column was also deconvoluted using maximum entropy. Deconvolution is useful in this type of system because the conservation of time dependent profiles depends on the band spreading processes in the chromatographic column, which might smooth out the finer details in the concentration profile. The method was also applied to the deconvolution of previously interpretted Pioneer Venus chromatograms. It was found in this case that the correct choice of peak shape function was critical to the sensitivity of maximum entropy in the reconstruction of these chromatograms.

Ultra-compact Marx-type high-voltage generator

DOEpatents

Goerz, David A.; Wilson, Michael J.

2000-01-01

An ultra-compact Marx-type high-voltage generator includes individual high-performance components that are closely coupled and integrated into an extremely compact assembly. In one embodiment, a repetitively-switched, ultra-compact Marx generator includes low-profile, annular-shaped, high-voltage, ceramic capacitors with contoured edges and coplanar extended electrodes used for primary energy storage; low-profile, low-inductance, high-voltage, pressurized gas switches with compact gas envelopes suitably designed to be integrated with the annular capacitors; feed-forward, high-voltage, ceramic capacitors attached across successive switch-capacitor-switch stages to couple the necessary energy forward to sufficiently overvoltage the spark gap of the next in-line switch; optimally shaped electrodes and insulator surfaces to reduce electric field stresses in the weakest regions where dissimilar materials meet, and to spread the fields more evenly throughout the dielectric materials, allowing them to operate closer to their intrinsic breakdown levels; and uses manufacturing and assembly methods to integrate the capacitors and switches into stages that can be arranged into a low-profile Marx generator.

Shaping ability and safety of five different rotary nickel-titanium instruments compared with stainless steel hand instrumentation in simulated curved root canals.

PubMed

Schirrmeister, Jörg F; Strohl, Christian; Altenburger, Markus J; Wrbas, Karl-Thomas; Hellwig, Elmar

2006-06-01

To compare the shaping ability and safety of engine-driven FlexMaster, GT Rotary, ProFile, ProTaper, and RaCe rotary instrumentation and Hedström hand instrumentation in simulated root canals. One hundred fifty simulated colored root canals with a curvature of 20 degrees and a radius of 10 mm were randomly distributed among 6 groups of 25 specimens each. After preparation to apical size 30 the area of remaining color on the canal wall indicating unprepared areas was measured in mm2 using image analyzer software. Specimens treated with RaCe left least areas of remaining color compared to all other groups (P < .001), followed by ProTaper. Preparation with ProFile left behind the highest amount of unprepared areas. The ProFile group revealed significantly more remaining color than ProTaper, GT Rotary, and FlexMaster (P < .05). Four FlexMaster files separated. RaCe rotary files were safe and more effective compared to the other instruments.

Airfoil shape for a turbine bucket

DOEpatents

Hyde, Susan Marie; By, Robert Romany; Tressler, Judd Dodge; Schaeffer, Jon Conrad; Sims, Calvin Levy

2005-06-28

Third stage turbine buckets have airfoil profiles substantially in accordance with Cartesian coordinate values of X, Y and Z set forth Table I wherein X and Y values are in inches and the Z values are non-dimensional values from 0 to 0.938 convertible to Z distances in inches by multiplying the Z values by the height of the airfoil in inches. The X and Y values are distances which, when connected by smooth continuing arcs, define airfoil profile sections at each distance Z. The profile sections at each distance Z are joined smoothly to one another to form a complete airfoil shape. The X and Y distances may be scalable as a function of the same constant or number to provide a scaled up or scaled down airfoil section for the bucket. The nominal airfoil given by the X, Y and Z distances lies within an envelop of .+-.0.150 inches in directions normal to the surface of the airfoil.

Turbine blade profile design method based on Bezier curves

NASA Astrophysics Data System (ADS)

Alexeev, R. A.; Tishchenko, V. A.; Gribin, V. G.; Gavrilov, I. Yu.

2017-11-01

In this paper, the technique of two-dimensional parametric blade profile design is presented. Bezier curves are used to create the profile geometry. The main feature of the proposed method is an adaptive approach of curve fitting to given geometric conditions. Calculation of the profile shape is produced by multi-dimensional minimization method with a number of restrictions imposed on the blade geometry.The proposed method has been used to describe parametric geometry of known blade profile. Then the baseline geometry was modified by varying some parameters of the blade. The numerical calculation of obtained designs has been carried out. The results of calculations have shown the efficiency of chosen approach.

The relationship between hand anthropometrics, total grip strength and individual finger force for various handle shapes.

PubMed

Kong, Yong-Ku; Kim, Dae-Min

2015-01-01

The design and shape of hand tool handles are critical factors for preventing musculoskeletal disorders (MSDs) caused by the use of hand tools. We explored how these factors are related to total force and individual finger force in males and females with various hand anthropometrics. Using the MFFM system, we assessed four indices of anthropometry, and measured total force and individual finger force on various handle designs and shapes. Both total force and individual finger force were significant according to gender and handle shape. Total grip strength to the handle shape indicated the greatest strength with D shape and the least with A shape. From the regression analysis of hand anthropometric indices, the value of R was respectably high at 0.608-0.696. The current study examined the gender and handle shape factors affecting grip strength based on the force measurements from various handle types, in terms of influence on different hand anthropometric indices.

Molecular filter-based diagnostics in high speed flows

NASA Technical Reports Server (NTRS)

Elliott, Gregory S.; Samimy, MO; Arnette, Stephen A.

1993-01-01

The use of iodine molecular filters in nonintrusive planar velocimetry methods is examined. Detailed absorption profiles are obtained to highlight the effects that determine the profile shape. It is shown that pressure broadening induced by the presence of a nonabsorbing vapor can be utilized to significantly change the slopes bounding the absorbing region while remaining in the optically-thick regime.

Plasma oscillations in spherical Gaussian shaped ultracold neutral plasma

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chen, Tianxing; Lu, Ronghua, E-mail: lurh@siom.ac.cn; Guo, Li

2016-04-15

The collective plasma oscillations are investigated in ultracold neutral plasma with a non-uniform density profile. Instead of the plane configuration widely used, we derive the plasma oscillation equations with spherically symmetric distribution and Gaussian density profile. The damping of radial oscillation is found. The Tonks–Dattner resonances of the ultracold neutral plasma with an applied RF field are also calculated.

Optimization of Root Section for Ultra-long Steam Turbine Rotor Blade

NASA Astrophysics Data System (ADS)

Hála, Jindřich; Luxa, Martin; Šimurda, David; Bobčík, Marek; Novák, Ondřej; Rudas, Bartoloměj; Synáč, Jaroslav

2018-04-01

This study presents the comparison of aerodynamic performances of two successive designs of the root profiles for the ultra-long rotor blade equipped with a straight fir-tree dovetail. Since aerodynamic and strength requirements laid upon the root section design are contradictory, it is necessary to aerodynamically optimize the design within the limits given by the foremost strength requirements. The most limiting criterion of the static strength is the size of the blade cross-section, which is determined by the number of blades in a rotor and also by the shape and size of a blade dovetail. The aerodynamic design requires mainly the zero incidence angle at the inlet of a profile and in the ideal case ensures that the load does not exceed a limit load condition. Moreover, the typical root profile cascades are transonic with supersonic exit Mach number, therefore, the shape of a suction side and a trailing edge has to respect transonic expansion of a working gas. In this paper, the two variants of root section profile cascades are compared and the aerodynamic qualities of both variants are verified using CFD simulation and two mutually independent experimental methods of measurements (optical and pneumatic).

Asymmetric simple exclusion process with position-dependent hopping rates: Phase diagram from boundary-layer analysis.

PubMed

Mukherji, Sutapa

2018-03-01

In this paper, we study a one-dimensional totally asymmetric simple exclusion process with position-dependent hopping rates. Under open boundary conditions, this system exhibits boundary-induced phase transitions in the steady state. Similarly to totally asymmetric simple exclusion processes with uniform hopping, the phase diagram consists of low-density, high-density, and maximal-current phases. In various phases, the shape of the average particle density profile across the lattice including its boundary-layer parts changes significantly. Using the tools of boundary-layer analysis, we obtain explicit solutions for the density profile in different phases. A detailed analysis of these solutions under different boundary conditions helps us obtain the equations for various phase boundaries. Next, we show how the shape of the entire density profile including the location of the boundary layers can be predicted from the fixed points of the differential equation describing the boundary layers. We discuss this in detail through several examples of density profiles in various phases. The maximal-current phase appears to be an especially interesting phase where the boundary layer flows to a bifurcation point on the fixed-point diagram.

Asymmetric simple exclusion process with position-dependent hopping rates: Phase diagram from boundary-layer analysis

NASA Astrophysics Data System (ADS)

Mukherji, Sutapa

2018-03-01

In this paper, we study a one-dimensional totally asymmetric simple exclusion process with position-dependent hopping rates. Under open boundary conditions, this system exhibits boundary-induced phase transitions in the steady state. Similarly to totally asymmetric simple exclusion processes with uniform hopping, the phase diagram consists of low-density, high-density, and maximal-current phases. In various phases, the shape of the average particle density profile across the lattice including its boundary-layer parts changes significantly. Using the tools of boundary-layer analysis, we obtain explicit solutions for the density profile in different phases. A detailed analysis of these solutions under different boundary conditions helps us obtain the equations for various phase boundaries. Next, we show how the shape of the entire density profile including the location of the boundary layers can be predicted from the fixed points of the differential equation describing the boundary layers. We discuss this in detail through several examples of density profiles in various phases. The maximal-current phase appears to be an especially interesting phase where the boundary layer flows to a bifurcation point on the fixed-point diagram.

Characterizing UT/LS O3 from Global Ozonesonde Profiles Using a Clustering Technique and Meteorological Reanalyses

NASA Astrophysics Data System (ADS)

Stauffer, R. M.; Thompson, A. M.

2017-12-01

Previous studies employing the self-organizing map (SOM) clustering technique to US ozonesonde data proved valuable for quantifying UT/LS O3 variability, and linking meteorological and chemical drivers to the shape of the ozone (O3) profile from the troposphere to the lower stratosphere. Focus has thus far been limited to specific geographical regions, but SOM has demonstrated the advantages of clustering over monthly climatological O3 averages, which mask day-to-day variability in the O3 profile and the correspondence between O3 and meteorology. We expand SOM to a global set of ozonesonde profiles, mostly from WOUDC, spanning 1980-present from 30 sites to evaluate global O3 climatologies and quantify links to geophysical processes for various meteorological regimes. Four clusters of O3 mixing ratio profiles are generated for each site, which show dominant profile shapes that correspond to site latitude. Offsets among O3 profile clusters and monthly O3 climatologies are 100s of ppbv in the UT/LS at higher latitude sites with active dynamics. Examination of meteorological reanalyses reveals a clear relationship among SOM clusters and covarying meteorological fields (geopotential height, potential vorticity, and tropopause height) for most sites. Tropical SOM clusters show marked dependence on velocity potential anomalies calculated from reanalysis winds, with low UT/LS O3 amounts corresponding to enhanced upper-level divergence, and vice versa. In addition to creating SOM cluster-based O3 climatologies, these results are meant to inform future approaches to validation of chemical transport models and satellite retrievals, which often struggle in the UT/LS region.

Fast-ion D(alpha) measurements and simulations in DIII-D

NASA Astrophysics Data System (ADS)

Luo, Yadong

The fast-ion Dalpha diagnostic measures the Doppler-shifted Dalpha light emitted by neutralized fast ions. For a favorable viewing geometry, the bright interferences from beam neutrals, halo neutrals, and edge neutrals span over a small wavelength range around the Dalpha rest wavelength and are blocked by a vertical bar at the exit focal plane of the spectrometer. Background subtraction and fitting techniques eliminate various contaminants in the spectrum. Fast-ion data are acquired with a time evolution of ˜1 ms, spatial resolution of ˜5 cm, and energy resolution of ˜10 keV. A weighted Monte Carlo simulation code models the fast-ion Dalpha spectra based on the fast-ion distribution function from other sources. In quiet plasmas, the spectral shape is in excellent agreement and absolute magnitude also has reasonable agreement. The fast-ion D alpha signal has the expected dependencies on plasma and neutral beam parameters. The neutral particle diagnostic and neutron diagnostic corroborate the fast-ion Dalpha measurements. The relative spatial profile is in agreement with the simulated profile based on the fast-ion distribution function from the TRANSP analysis code. During ion cyclotron heating, fast ions with high perpendicular energy are accelerated, while those with low perpendicular energy are barely affected. The spatial profile is compared with the simulated profiles based on the fast-ion distribution functions from the CQL Fokker-Planck code. In discharges with Alfven instabilities, both the spatial profile and spectral shape suggests that fast ions are redistributed. The flattened fast-ion Dalpha profile is in agreement with the fast-ion pressure profile.

Dynamic laser beam shaping for material processing using hybrid holograms

NASA Astrophysics Data System (ADS)

Liu, Dun; Wang, Yutao; Zhai, Zhongsheng; Fang, Zheng; Tao, Qing; Perrie, Walter; Edwarson, Stuart P.; Dearden, Geoff

2018-06-01

A high quality, dynamic laser beam shaping method is demonstrated by displaying a series of hybrid holograms onto a spatial light modulator (SLM), while each one of the holograms consists of a binary grating and a geometric mask. A diffraction effect around the shaped beam has been significantly reduced. Beam profiles of arbitrary shape, such as square, ring, triangle, pentagon and hexagon, can be conveniently obtained by loading the corresponding holograms on the SLM. The shaped beam can be reconstructed in the range of 0.5 mm at the image plane. Ablation on a polished stainless steel sample at the image plane are consistent with the beam shape at the diffraction near-field. The ±1st order and higher order beams can be completely removed when the grating period is smaller than 160 μm. The local energy ratio of the shaped beam observed by the CCD camera is up to 77.67%. Dynamic processing at 25 Hz using different shapes has also been achieved.

Glacially-derived overpressure in the northeastern Alaskan subduction zone: combined tomographic and morphometric analysis of shallow sediments on the Yakutat shelf and slope, Gulf of Alaska

NASA Astrophysics Data System (ADS)

Clary, W. A.; Worthington, L. L.; Scuderi, L. A.; Daigle, H.; Swartz, J. M.

2017-12-01

The Pamplona zone fold and thrust belt is the offshore expression of convergence and shallow subduction of the Yakutat microplate beneath North America in the northeastern Alaska subduction zone. The combination of convergent tectonics and glaciomarine sedimentary processes create patterns of deformation and deposition resulting in a shallow sedimentary sequence with varying compaction, fluid pressure, and fault activity. We propose that velocity variations observed in our tomographic analysis represent long-lived fluid overpressure due to loading by ice sheets and sediments. Regions with bathymetric and stratigraphic evidence of recent ice sheets and associated sedimentation should be collocated with evidence of overpressure (seismic low velocity zones) in the shallow sediments. Here, we compare a velocity model with shelf seismic stratigraphic facies and modern seafloor morphology. To document glacially derived morphology we use high resolution bathymetry to identify channel and gully networks on the western Yakutat shelf-slope then analyze cross-channel shape indices across the study area. We use channel shape index measurements as a proxy of recent ice-proximal sedimentation based on previously published results that proposed a close correlation. Profiles taken at many locations were fitted with a power function and assigned a shape - U-shape channels likely formed proximal to recent ice advances. Detailed velocity models were created by a combination of streamer tomography and pre-stack depth migration velocities with seismic data including: a 2008 R/V Langseth dataset from the St. Elias Erosion and Tectonics Project (STEEP); and a 2004 high-resolution R/V Ewing dataset. Velocity-porosity-permeability relationships developed using IODP Expedition 341 drilling data inform interpretation and physical properties analyses of the shallow sediments. Initial results from a 35 km profile extending SE seaward of the Bering glacier and subparallel to the Bering trough suggest a spatial relationship between the extent of U-shaped profiles and low-velocity shallow sediments. Towards the SE end of the model we observe a large overlap of U-shaped indices, and a shallow low-velocity zone in the mapped extent of the last glacial maximum suggestive of overpressure due to loading by ice sheet activity.

5.7  W cw single-frequency laser at 671  nm by single-pass second harmonic generation of a 17.2  W injection-locked 1342  nm Nd : YVO4 ring laser using periodically poled MgO : LiNbO3.

PubMed

Koch, Peter; Ruebel, Felix; Bartschke, Juergen; L'huillier, Johannes A

2015-11-20

We demonstrate a continuous wave single-frequency laser at 671.1 nm based on a high-power 888 nm pumped Nd:YVO4 ring laser at 1342.2 nm. Unidirectional operation of the fundamental ring laser is achieved with the injection-locking technique. A Nd:YVO4 microchip laser serves as the injecting seed source, providing a tunable single-frequency power of up to 40 mW. The ring laser emits a single-frequency power of 17.2 W with a Gaussian beam profile and a beam propagation factor of M2<1.1. A 60-mm-long periodically poled MgO-doped LiNbO3 crystal is used to generate the second harmonic in a single-pass scheme. Up to 5.7 W at 671.1 nm with a Gaussian shaped beam profile and a beam propagation factor of M2<1.2 are obtained, which is approximately twice the power of previously reported lasers. This work opens possibilities in cold atoms experiments with lithium, allowing the use of larger ensembles in magneto-optical traps or higher diffraction orders in atomic beam interferometers.

A standardization model based on image recognition for performance evaluation of an oral scanner.

PubMed

Seo, Sang-Wan; Lee, Wan-Sun; Byun, Jae-Young; Lee, Kyu-Bok

2017-12-01

Accurate information is essential in dentistry. The image information of missing teeth is used in optically based medical equipment in prosthodontic treatment. To evaluate oral scanners, the standardized model was examined from cases of image recognition errors of linear discriminant analysis (LDA), and a model that combines the variables with reference to ISO 12836:2015 was designed. The basic model was fabricated by applying 4 factors to the tooth profile (chamfer, groove, curve, and square) and the bottom surface. Photo-type and video-type scanners were used to analyze 3D images after image capture. The scans were performed several times according to the prescribed sequence to distinguish the model from the one that did not form, and the results confirmed it to be the best. In the case of the initial basic model, a 3D shape could not be obtained by scanning even if several shots were taken. Subsequently, the recognition rate of the image was improved with every variable factor, and the difference depends on the tooth profile and the pattern of the floor surface. Based on the recognition error of the LDA, the recognition rate decreases when the model has a similar pattern. Therefore, to obtain the accurate 3D data, the difference of each class needs to be provided when developing a standardized model.

Novel use of a Dektak 150 surface profiler unmasks differences in resorption pit profiles between control and Charcot patient osteoclasts.

PubMed

Petrova, Nina L; Petrov, Peter K; Edmonds, Michael E; Shanahan, Catherine M

2014-04-01

We hypothesized that newly formed osteoclasts from patients with acute Charcot osteoarthropathy can resorb surfaces of bone more extensively compared with controls. Peripheral blood monocytes, isolated from eight Charcot patients and nine controls, were cultured in vitro on 24-well plates and bovine bone discs in duplicate with macrophage colony-stimulating factor (M-CSF) and receptor activator of nuclear factor κβ ligand (RANKL). Osteoclast formation was assessed by tartrate-resistant acid phosphatase staining (TRAcP) at day 17. Resorption was measured at day 21 after toluidine blue staining by two methods: (1) area of resorption at the surface by image analysis (%) and (2) area of resorption under the surface (μm(2)) measured by a Dektak 150 Surface Profiler. Ten 1,000 μm-long scans were performed per disc. Pits were classified as unidented, bidented, and multidented according to their shape. Although the number of newly formed TRAcP positive multinucleated cells (>3 nuclei) was similar in M-CSF + RANKL-treated cultures between controls and Charcot patients, the latter exhibited increased resorbing activity. The area of resorption on the surface by image analysis was significantly greater in Charcot patients compared with controls (21.1 % [14.5-26.2] vs. 40.8 % [35.4-46.0], median [25-75th percentile], p < 0.01), as was the area of resorption under the surface (2.7 x 10(3) μm(2) [1.6 x 10(3)- 3.9 x 10(3)] vs. 8.3 x 10(3) μm (2) [5.6 x 10(3)- 10.6 x 10(3), [corrected] p < 0.01) after profilometry. In Charcot patients pits were deeper and wider and more frequently presented as multidented pits. This application of the Dektak 150 Surface Profiler revealed novel differences in resorption pit profile from osteoclasts derived from Charcot patients compared with controls. Resorption in Charcot patients was mediated by highly aggressive newly formed osteoclasts from monocytes eroding large and deep areas of bone.

TU-F-CAMPUS-T-04: Variations in Nominally Identical Small Fields From Photon Jaw Reproducibility and Associated Effects On Small Field Dosimetric Parameters

DOE Office of Scientific and Technical Information (OSTI.GOV)

Muir, B R; McEwen, M R

2015-06-15

Purpose: To investigate uncertainties in small field output factors and detector specific correction factors from variations in field size for nominally identical fields using measurements and Monte Carlo simulations. Methods: Repeated measurements of small field output factors are made with the Exradin W1 (plastic scintillation detector) and the PTW microDiamond (synthetic diamond detector) in beams from the Elekta Precise linear accelerator. We investigate corrections for a 0.6x0.6 cm{sup 2} nominal field size shaped with secondary photon jaws at 100 cm source to surface distance (SSD). Measurements of small field profiles are made in a water phantom at 10 cm depthmore » using both detectors and are subsequently used for accurate detector positioning. Supplementary Monte Carlo simulations with EGSnrc are used to calculate the absorbed dose to the detector and absorbed dose to water under the same conditions when varying field size. The jaws in the BEAMnrc model of the accelerator are varied by a reasonable amount to investigate the same situation without the influence of measurements uncertainties (such as detector positioning or variation in beam output). Results: For both detectors, small field output factor measurements differ by up to 11 % when repeated measurements are made in nominally identical 0.6x0.6 cm{sup 2} fields. Variations in the FWHM of measured profiles are consistent with field size variations reported by the accelerator. Monte Carlo simulations of the dose to detector vary by up to 16 % under worst case variations in field size. These variations are also present in calculations of absorbed dose to water. However, calculated detector specific correction factors are within 1 % when varying field size because of cancellation of effects. Conclusion: Clinical physicists should be aware of potentially significant uncertainties in measured output factors required for dosimetry of small fields due to field size variations for nominally identical fields.« less

Capillary-tube-based extension of thermoacoustic theory for a random medium

NASA Astrophysics Data System (ADS)

Roh, Heui-Seol; Raspet, Richard; Bass, Henry E.

2005-09-01

Thermoacoustic theory for a single capillary tube is extended to random bulk medium on the basis of capillary tubes. The characteristics of the porous stack inside the resonator such as the tortuosity, dynamic shape factor, and porosity are introduced for the extension of wave equation by following Attenborough's approach. Separation of the dynamic shape factor for the viscous and thermal effect is adopted and scaling using the dynamic shape factor and tortuosity factor is demonstrated. The theoretical and experimental comparison of thermoviscous functions in reticulated vitreous carbon (RVC) and aluminum foam shows reasonable agreement. The extension is useful for investigations of the properties of a stack with arbitrary shapes of non-parallel pores.

Simulated X-ray galaxy clusters at the virial radius: Slopes of the gas density, temperature and surface brightness profiles

NASA Astrophysics Data System (ADS)

Roncarelli, M.; Ettori, S.; Dolag, K.; Moscardini, L.; Borgani, S.; Murante, G.

2006-12-01

Using a set of hydrodynamical simulations of nine galaxy clusters with masses in the range 1.5 × 1014 < Mvir < 3.4 × 1015Msolar, we have studied the density, temperature and X-ray surface brightness profiles of the intracluster medium in the regions around the virial radius. We have analysed the profiles in the radial range well above the cluster core, the physics of which are still unclear and matter of tension between simulated and observed properties, and up to the virial radius and beyond, where present observations are unable to provide any constraints. We have modelled the radial profiles between 0.3R200 and 3R200 with power laws with one index, two indexes and a rolling index. The simulated temperature and [0.5-2] keV surface brightness profiles well reproduce the observed behaviours outside the core. The shape of all these profiles in the radial range considered depends mainly on the activity of the gravitational collapse, with no significant difference among models including extraphysics. The profiles steepen in the outskirts, with the slope of the power-law fit that changes from -2.5 to -3.4 in the gas density, from -0.5 to -1.8 in the gas temperature and from -3.5 to -5.0 in the X-ray soft surface brightness. We predict that the gas density, temperature and [0.5-2] keV surface brightness values at R200 are, on average, 0.05, 0.60, 0.008 times the measured values at 0.3R200. At 2R200, these values decrease by an order of magnitude in the gas density and surface brightness, by a factor of 2 in the temperature, putting stringent limits on the detectable properties of the intracluster-medium (ICM) in the virial regions.

GATA3 acts upstream of FOXA1 in mediating ESR1 binding by shaping enhancer accessibility.

PubMed

Theodorou, Vasiliki; Stark, Rory; Menon, Suraj; Carroll, Jason S

2013-01-01

Estrogen receptor (ESR1) drives growth in the majority of human breast cancers by binding to regulatory elements and inducing transcription events that promote tumor growth. Differences in enhancer occupancy by ESR1 contribute to the diverse expression profiles and clinical outcome observed in breast cancer patients. GATA3 is an ESR1-cooperating transcription factor mutated in breast tumors; however, its genomic properties are not fully defined. In order to investigate the composition of enhancers involved in estrogen-induced transcription and the potential role of GATA3, we performed extensive ChIP-sequencing in unstimulated breast cancer cells and following estrogen treatment. We find that GATA3 is pivotal in mediating enhancer accessibility at regulatory regions involved in ESR1-mediated transcription. GATA3 silencing resulted in a global redistribution of cofactors and active histone marks prior to estrogen stimulation. These global genomic changes altered the ESR1-binding profile that subsequently occurred following estrogen, with events exhibiting both loss and gain in binding affinity, implying a GATA3-mediated redistribution of ESR1 binding. The GATA3-mediated redistributed ESR1 profile correlated with changes in gene expression, suggestive of its functionality. Chromatin loops at the TFF locus involving ESR1-bound enhancers occurred independently of ESR1 when GATA3 was silenced, indicating that GATA3, when present on the chromatin, may serve as a licensing factor for estrogen-ESR1-mediated interactions between cis-regulatory elements. Together, these experiments suggest that GATA3 directly impacts ESR1 enhancer accessibility, and may potentially explain the contribution of mutant-GATA3 in the heterogeneity of ESR1+ breast cancer.

GATA3 acts upstream of FOXA1 in mediating ESR1 binding by shaping enhancer accessibility

PubMed Central

Theodorou, Vasiliki; Stark, Rory; Menon, Suraj; Carroll, Jason S.

2013-01-01

Estrogen receptor (ESR1) drives growth in the majority of human breast cancers by binding to regulatory elements and inducing transcription events that promote tumor growth. Differences in enhancer occupancy by ESR1 contribute to the diverse expression profiles and clinical outcome observed in breast cancer patients. GATA3 is an ESR1-cooperating transcription factor mutated in breast tumors; however, its genomic properties are not fully defined. In order to investigate the composition of enhancers involved in estrogen-induced transcription and the potential role of GATA3, we performed extensive ChIP-sequencing in unstimulated breast cancer cells and following estrogen treatment. We find that GATA3 is pivotal in mediating enhancer accessibility at regulatory regions involved in ESR1-mediated transcription. GATA3 silencing resulted in a global redistribution of cofactors and active histone marks prior to estrogen stimulation. These global genomic changes altered the ESR1-binding profile that subsequently occurred following estrogen, with events exhibiting both loss and gain in binding affinity, implying a GATA3-mediated redistribution of ESR1 binding. The GATA3-mediated redistributed ESR1 profile correlated with changes in gene expression, suggestive of its functionality. Chromatin loops at the TFF locus involving ESR1-bound enhancers occurred independently of ESR1 when GATA3 was silenced, indicating that GATA3, when present on the chromatin, may serve as a licensing factor for estrogen–ESR1-mediated interactions between cis-regulatory elements. Together, these experiments suggest that GATA3 directly impacts ESR1 enhancer accessibility, and may potentially explain the contribution of mutant-GATA3 in the heterogeneity of ESR1+ breast cancer. PMID:23172872

Turbulent fluctuations during pellet injection into a dipole confined plasma torus

NASA Astrophysics Data System (ADS)

Garnier, D. T.; Mauel, M. E.; Roberts, T. M.; Kesner, J.; Woskov, P. P.

2017-01-01

We report measurements of the turbulent evolution of the plasma density profile following the fast injection of lithium pellets into the Levitated Dipole Experiment (LDX) [Boxer et al., Nat. Phys. 6, 207 (2010)]. As the pellet passes through the plasma, it provides a significant internal particle source and allows investigation of density profile evolution, turbulent relaxation, and turbulent fluctuations. The total electron number within the dipole plasma torus increases by more than a factor of three, and the central density increases by more than a factor of five. During these large changes in density, the shape of the density profile is nearly "stationary" such that the gradient of the particle number within tubes of equal magnetic flux vanishes. In comparison to the usual case, when the particle source is neutral gas at the plasma edge, the internal source from the pellet causes the toroidal phase velocity of the fluctuations to reverse and changes the average particle flux at the plasma edge. An edge particle source creates an inward turbulent pinch, but an internal particle source increases the outward turbulent particle flux. Statistical properties of the turbulence are measured by multiple microwave interferometers and by an array of probes at the edge. The spatial structures of the largest amplitude modes have long radial and toroidal wavelengths. Estimates of the local and toroidally averaged turbulent particle flux show intermittency and a non-Gaussian probability distribution function. The measured fluctuations, both before and during pellet injection, have frequency and wavenumber dispersion consistent with theoretical expectations for interchange and entropy modes excited within a dipole plasma torus having warm electrons and cool ions.

Seismic responses and controlling factors of Miocene deepwater gravity-flow deposits in Block A, Lower Congo Basin

NASA Astrophysics Data System (ADS)

Wang, Linlin; Wang, Zhenqi; Yu, Shui; Ngia, Ngong Roger

2016-08-01

The Miocene deepwater gravity-flow sedimentary system in Block A of the southwestern part of the Lower Congo Basin was identified and interpreted using high-resolution 3-D seismic, drilling and logging data to reveal development characteristics and main controlling factors. Five types of deepwater gravity-flow sedimentary units have been identified in the Miocene section of Block A, including mass transport, deepwater channel, levee, abandoned channel and sedimentary lobe deposits. Each type of sedimentary unit has distinct external features, internal structures and lateral characteristics in seismic profiles. Mass transport deposits (MTDs) in particular correspond to chaotic low-amplitude reflections in contact with mutants on both sides. The cross section of deepwater channel deposits in the seismic profile is in U- or V-shape. The channel deposits change in ascending order from low-amplitude, poor-continuity, chaotic filling reflections at the bottom, to high-amplitude, moderate to poor continuity, chaotic or sub-parallel reflections in the middle section and to moderate-weak amplitude, good continuity, parallel or sub-parallel reflections in the upper section. The sedimentary lobes are laterally lobate, which corresponds to high-amplitude, good-continuity, moundy reflection signatures in the seismic profile. Due to sediment flux, faults, and inherited terrain, few mass transport deposits occur in the northeastern part of the study area. The front of MTDs is mainly composed of channel-levee complex deposits, while abandoned-channel and lobe-deposits are usually developed in high-curvature channel sections and the channel terminals, respectively. The distribution of deepwater channel, levee, abandoned channel and sedimentary lobe deposits is predominantly controlled by relative sea level fluctuations and to a lesser extent by tectonism and inherited terrain.

Turbulent fluctuations during pellet injection into a dipole confined plasma torus

DOE PAGES

Garnier, D. T.; Mauel, M. E.; Roberts, T. M.; ...

2017-01-01

Here, we report measurements of the turbulent evolution of the plasma density profile following the fast injection of lithium pellets into the Levitated Dipole Experiment (LDX) [Boxer et al., Nat. Phys. 6, 207 (2010)]. As the pellet passes through the plasma, it provides a significant internal particle source and allows investigation of density profile evolution, turbulent relaxation, and turbulent fluctuations. The total electron number within the dipole plasma torus increases by more than a factor of three, and the central density increases by more than a factor of five. During these large changes in density, the shape of the densitymore » profile is nearly “stationary” such that the gradient of the particle number within tubes of equal magnetic flux vanishes. In comparison to the usual case, when the particle source is neutral gas at the plasma edge, the internal source from the pellet causes the toroidal phase velocity of the fluctuations to reverse and changes the average particle flux at the plasma edge. An edge particle source creates an inward turbulent pinch, but an internal particle source increases the outward turbulent particle flux. Statistical properties of the turbulence are measured by multiple microwave interferometers and by an array of probes at the edge. The spatial structures of the largest amplitude modes have long radial and toroidal wavelengths. Estimates of the local and toroidally averaged turbulent particle flux show intermittency and a non-Gaussian probability distribution function. The measured fluctuations, both before and during pellet injection, have frequency and wave number dispersion consistent with theoretical expectations for interchange and entropy modes excited within a dipole plasma torus having warm electrons and cool ions.« less

Autonomous Slat-Cove-Filler Device for Reduction of Aeroacoustic Noise Associated with Aircraft Systems

NASA Technical Reports Server (NTRS)

Turner, Travis L. (Inventor); Kidd, Reggie T. (Inventor); Lockard, David P (Inventor); Khorrami, Mehdi R. (Inventor); Streett, Craig L. (Inventor); Weber, Douglas Leo (Inventor)

2016-01-01

A slat cove filler is utilized to reduce airframe noise resulting from deployment of a leading edge slat of an aircraft wing. The slat cove filler is preferably made of a super elastic shape memory alloy, and the slat cove filler shifts between stowed and deployed shapes as the slat is deployed. The slat cove filler may be configured such that a separate powered actuator is not required to change the shape of the slat cove filler from its deployed shape to its stowed shape and vice-versa. The outer contour of the slat cove filler preferably follows a profile designed to maintain accelerating flow in the gap between the slat cove filler and wing leading edge to provide for noise reduction.

Characterization of equipment for shaping and imaging hadron minibeams

NASA Astrophysics Data System (ADS)

Pugatch, V.; Brons, S.; Campbell, M.; Kovalchuk, O.; Llopart, X.; Martínez-Rovira, I.; Momot, Ie.; Okhrimenko, O.; Prezado, Y.; Sorokin, Yu.

2017-11-01

For the feasibility studies of spatially fractionated hadron therapy prototypes of the equipment for hadron minibeams shaping and monitoring have been designed, built and tested. The collimators design was based on Monte Carlo simulations (Gate v.6.2). Slit and matrix collimators were used for minibeams shaping. Gafchromic films, micropixel detectors Timepix in a hybrid as well as metal mode were tested for measuring hadrons intensity distribution in minibeams. An overall beam profile was measured by the metal microstrip detector. The performance of a mini-beams shaping and monitoring equipment was characterized exploring low energy protons at the KINR Tandem generator as well as high energy carbon and oxygen ion beams at HIT (Heidelberg). The results demonstrate reliable performance of the tested equipment for shaping and imaging hadron mini-beam structures.

Temperature Models for the Mexican Subduction Zone

NASA Astrophysics Data System (ADS)

Manea, V. C.; Kostoglodov, V.; Currie, C.; Manea, M.; Wang, K.

2002-12-01

It is well known that the temperature is one of the major factors which controls the seismogenic zone. The Mexican subduction zone is characterized by a very shallow flat subducting interplate in its central part (Acapulco, Oaxaca), and deeper subduction slabs northern (Jalisco) and southern (Chiapas). It has been proposed that the seismogenic zone is controlled, among other factors, by a temperature. Therefore, we have developed four two-dimensional steady state thermal models for Jalisco, Guerrero, Oaxaca and Chiapas. The updip limit of the seismogenic zone is taken between 100 §C and 150 §C, while the downdip limit is thought to be at 350 §C because of the transition from stick-slip to stable-sliding. The shape of the subducting plate is inferred from gravity and seismicity. The convergence velocity between oceanic and continental lithospheric plates is taken as the following: 5 cm/yr for Jalisco profile, 5.5 for Guerrero profile, 5.8 for Oaxaca profile, and 7.8 for Chiapas profile. The age of the subducting plates, since they are young, and provides the primary control on the forearc thermal structure, are as the following: 11 My for Jalisco profile, 14.5 My for Guerrero profile, 15 My for Oaxaca profile, and 28 My for Chiapas profile. We also introduced in the models a small quantity of frictional heating (pore pressure ratio 0.98). The value of 0.98 for pore pressure ratio was obtained for the Guerrero profile, in order to fit the intersection between the 350 §C isotherm and the subducting plate at 200 Km from trench. The value of 200 km coupling zone from trench is inferred from GPS data for the steady interseismic period and also for the last slow aseismic slip that occurred in Guerrero in 2002. We have used this value of pore pressure ratio (0.98) for all the other profiles. For the others three profiles we obtained the following coupling extents: Jalisco - 100 km, Oaxaca - 170 km and Chiapas - 125 km (from the trench). Independent constrains of the thermal models come from the surface thermal measurements (offshore - Prol-Ledesma et al (1989) and onshore - Ziagos et al. (1985)). Unfortunately these measurements are very sparse, and present an important dispersion and have large uncertainties. In our models, all profiles show a decrease in heat flow from the trench towards the continent, which is characteristic for subduction zones. We also have included a mantle wedge flow current in order to keep a constant depth to the lithosphere-asthenosphere boundary. This mantle wedge convection provides an increase in heat flow near the volcanic arc which is consistent with the surface observations. Our models indicate that the seismogenic zone in Mexico comprised between 100 §C and 350 §C is in good agreement with the coseismic rupture width inferred from the megathrust earthquake aftershocks and seismic models of rupture. These thermal models will be used to calculate the thermal stresses induced by the subducting plate.

A numerical algorithm of tooth profile of non-circular cylindrical gear

NASA Astrophysics Data System (ADS)

Wang, Xuan

2017-08-01

Non-circular cylindrical gear (NCCG) is a common form of non-circular gear. Different from the circular gear, the tooth profile equation of NCCG cannot be obtained. So it is necessary to use a numerical algorithm to calculate the tooth profile of NCCG. For this reason, this paper presents a simple and highly efficient numerical algorithm to obtain the tooth profile of NCCG. Firstly, the mathematical model of tooth profile envelope of NCCG is established based on the principle of gear shaping, and the tooth profile envelope of NCCG is obtained. Secondly, the polar radius and polar angle of shaper cutter tooth profile are chosen as the criterions, by which the points of NCCG tooth cogging can be screened out. Finally, the boundary of tooth cogging points is extracted by a distance criterion and correspondingly the tooth profile of NCCG is obtained.

A protocol for the creation of useful geometric shape metrics illustrated with a newly derived geometric measure of leaf circularity.

PubMed

Krieger, Jonathan D

2014-08-01

I present a protocol for creating geometric leaf shape metrics to facilitate widespread application of geometric morphometric methods to leaf shape measurement. • To quantify circularity, I created a novel shape metric in the form of the vector between a circle and a line, termed geometric circularity. Using leaves from 17 fern taxa, I performed a coordinate-point eigenshape analysis to empirically identify patterns of shape covariation. I then compared the geometric circularity metric to the empirically derived shape space and the standard metric, circularity shape factor. • The geometric circularity metric was consistent with empirical patterns of shape covariation and appeared more biologically meaningful than the standard approach, the circularity shape factor. The protocol described here has the potential to make geometric morphometrics more accessible to plant biologists by generalizing the approach to developing synthetic shape metrics based on classic, qualitative shape descriptors.

The role of stellar radial motions in shaping galaxy surface brightness profiles

NASA Astrophysics Data System (ADS)

Ruiz-Lara, T.; Few, C. G.; Florido, E.; Gibson, B. K.; Pérez, I.; Sánchez-Blázquez, P.

2017-12-01

Aims: The physics driving features such as breaks observed in galaxy surface brightness (SB) profiles remains contentious. Here, we assess the importance of stellar radial motions in shaping their characteristics. Methods: We use the simulated Milky Way-mass cosmological discs from the Ramses Disc Environment Study (RaDES) to characterise the radial redistribution of stars in galaxies displaying type-I (pure exponentials), II (downbending), and III (upbending) SB profiles. We compare radial profiles of the mass fractions and the velocity dispersions of different sub-populations of stars according to their birth and current location. Results: Radial redistribution of stars is important in all galaxies regardless of their light profiles. Type-II breaks seem to be a consequence of the combined effects of outward-moving and accreted stars. The former produce shallower inner profiles (lack of stars in the inner disc) and accumulate material around the break radius and beyond, strengthening the break; the latter can weaken or even convert the break into a pure exponential. Further accretion from satellites can concentrate material in the outermost parts, leading to type-III breaks that can coexist with type-II breaks, but situated further out. Type-III galaxies would be the result of an important radial redistribution of material throughout the entire disc, as well as a concentration of accreted material in the outskirts. In addition, type-III galaxies display the most efficient radial redistribution and the largest number of accreted stars, followed by type-I and II systems, suggesting that type-I galaxies may be an intermediate case between types II and III. In general, the velocity dispersion profiles of all galaxies tend to flatten or even increase around the locations where the breaks are found. The age and metallicity profiles are also affected, exhibiting different inner gradients depending on their SB profile, being steeper in the case of type-II systems (as found observationally). The steep type-II profiles might be inherent to their formation rather than acquired via radial redistribution.

The Different Faces of San Francisco's Ocean Beach: Analyzing Sand Size and Beach Shape

NASA Astrophysics Data System (ADS)

Grove, K.; Labit, R.; Lui, S.; Rodriquez, I.; Yi, C.; Yu, M.

2004-12-01

Ocean Beach is located along the western edge of San Francisco adjacent to the Pacific Ocean. Erosion along the southern part of the beach is threatening a nearby highway and water treatment plant. To better understand this beach and the processes that form it, our SF-ROCKS research group collected data from seven locations along its length. We used an auto-level surveying instrument to measure beach profiles and we collected sand samples that were measured using sieves and a sieve shaker. We plotted profiles and grain-size data using Excel and Surfer software. The sediment is mostly fine sand, and the means of all samples range between 0.19-0.26 mm. There may be little variation along the beach because only small sand grains have survived the long journey from their Sierra Nevada source. Profile shape does vary along the beach. The profile at the northern end is about three times wider than the profile at the southern end. The northern profile is flatter overall, but all profiles had a steep beach face in August, when the data were collected. The differences in beach profiles may be related to position relative to the offshore bar, which appears to provide sand to the northern part of the beach. Our group will collect more data in November to see what changes have occurred after the large-wave season has begun. We will use Surfer software to compare summer and fall profiles, to see where sediment has been added and where sediment has been removed. We will also compare our results to the data collected by Dr. Patrick Barnard and his research group at the U.S. Geological Survey, who are using an All-Terrain Vehicle to measure beach profiles and a camera to measure sediment size. We will use our analysis of beach variations to make recommendations for reducing beach erosion.

Lensing Constraints on the Mass Profile Shape and the Splashback Radius of Galaxy Clusters

NASA Astrophysics Data System (ADS)

Umetsu, Keiichi; Diemer, Benedikt

2017-02-01

The lensing signal around galaxy clusters can, in principle, be used to test detailed predictions for their average mass profile from numerical simulations. However, the intrinsic shape of the profiles can be smeared out when a sample that spans a wide range of cluster masses is averaged in physical length units. This effect especially conceals rapid changes in gradient such as the steep drop associated with the splashback radius, a sharp edge corresponding to the outermost caustic in accreting halos. We optimize the extraction of such local features by scaling individual halo profiles to a number of spherical overdensity radii, and apply this method to 16 X-ray-selected, high-mass clusters targeted in the Cluster Lensing And Supernova survey with Hubble. By forward-modeling the weak- and strong-lensing data presented by Umetsu et al., we show that, regardless of the scaling overdensity, the projected ensemble density profile is remarkably well described by a Navarro-Frenk-White (NFW) or Einasto profile out to R˜ 2.5 {h}-1 {Mpc}, beyond which the profiles flatten. We constrain the NFW concentration to {c}200{{c}}=3.66+/- 0.11 at {M}200{{c}}≃ 1.0× {10}15 {h}-1 {M}⊙ , consistent with and improved from previous work that used conventionally stacked lensing profiles, and in excellent agreement with theoretical expectations. Assuming the profile form of Diemer & Kravtsov and generic priors calibrated from numerical simulations, we place a lower limit on the splashback radius of the cluster halos, if it exists, of {R}{sp}3{{D}}/{r}200{{m}}> 0.89 ({R}{sp}3{{D}}> 1.83 {h}-1 {Mpc}) at 68% confidence. The corresponding density feature is most pronounced when the cluster profiles are scaled by {r}200{{m}}, and smeared out when scaled to higher overdensities. Based in part on data collected at the Subaru Telescope, which is operated by the National Astronomical Society of Japan.

Environmental factors that shape biofilm formation.

PubMed

Toyofuku, Masanori; Inaba, Tomohiro; Kiyokawa, Tatsunori; Obana, Nozomu; Yawata, Yutaka; Nomura, Nobuhiko

2016-01-01

Cells respond to the environment and alter gene expression. Recent studies have revealed the social aspects of bacterial life, such as biofilm formation. Biofilm formation is largely affected by the environment, and the mechanisms by which the gene expression of individual cells affects biofilm development have attracted interest. Environmental factors determine the cell's decision to form or leave a biofilm. In addition, the biofilm structure largely depends on the environment, implying that biofilms are shaped to adapt to local conditions. Second messengers such as cAMP and c-di-GMP are key factors that link environmental factors with gene regulation. Cell-to-cell communication is also an important factor in shaping the biofilm. In this short review, we will introduce the basics of biofilm formation and further discuss environmental factors that shape biofilm formation. Finally, the state-of-the-art tools that allow us investigate biofilms under various conditions are discussed.

A Twin Factor Mixture Modeling Approach to Childhood Temperament: Differential Heritability

PubMed Central

Scott, Brandon G.; Lemery-Chalfant, Kathryn; Clifford, Sierra; Tein, Jenn-Yun; Stoll, Ryan; Goldsmith, H. Hill

2016-01-01

Twin factor mixture modeling was used to identify temperament profiles, while simultaneously estimating a latent factor model for each profile with a sample of 787 twin pairs (Mage =7.4 years; SD = .84; 49% female; 88.3% Caucasian), using mother- and father-reported temperament. A 4-profile, 1-factor model fit the data well. Profiles included ‘Regulated, Typical Reactive’, ‘Well-regulated, Positive Reactive’, ‘Regulated, Surgent’, and ‘Dysregulated, Negative Reactive.’ All profiles were heritable, with heritability lower and shared environment also contributing to membership in the ‘Regulated, Typical Reactive’ and ‘Dysregulated, Negative Reactive’ profiles. PMID:27291568

An Analysis of Water Line Profiles in Star Formation Regions Observed by SWAS

NASA Technical Reports Server (NTRS)

Ashby, Matthew L. N.; Bergin, Edwin A.; Plume, Rene; Carpenter, John M.; Neufeld, David A.; Chin, Gordon; Erickson, Neal R.; Goldsmith, Paul F.; Harwit, Martin; Howe, J. E.

2000-01-01

We present spectral line profiles for the 557 GHz 1(sub 1,0) yields 1(sub 0,1) ground-state rotational transition of ortho-H2(16)O for 18 galactic star formation regions observed by SWAS. 2 Water is unambiguously detected in every source. The line profiles exhibit a wide variety of shapes, including single-peaked spectra and self-reversed profiles. We interpret these profiles using a Monte Carlo code to model the radiative transport. The observed variations in the line profiles can be explained by variations in the relative strengths of the bulk flow and small-scale turbulent motions within the clouds. Bulk flow (infall, outflow) must be present in some cloud cores, and in certain cases this bulk flow dominates the turbulent motions.

Long-Term Time Variability in the X-Ray Pulse Shape of the Crab Nebula Pulsar

NASA Astrophysics Data System (ADS)

Fazio, Giovanni G.

2000-01-01

This is the final performance report for our grant 'Long-Term Time Variability in the X-Ray Pulse Shape of the Crab Nebula Pulsar.' In the first year of this grant, we received the 50,000-second ROSAT (German acronym for X-ray satellite) High Resolution Images (HRI) observation of the Crab Nebula pulsar. We used the data to create a 65-ms-resolution pulse profile and compared it to a similar pulse profile obtained in 1991. No statistically significant differences were found. These results were presented at the January 1998 meeting of the American Astronomical Society. Since then, we have performed more sensitive analyses to search for potential changes in the pulse profile shape between the two data sets. Again, no significant variability was found. In order to augment this long (six-year) baseline data set, we have analyzed archival observations of the Crab Nebula pulsar with the Rossi X-Ray Timing Explorer (RXTE). While these observations have shorter time baselines than the ROSAT data set, their higher signal-to-noise offers similar sensitivity to long-term variability. Again, no significant variations have been found, confirming our ROSAT results. This work was done in collaboration with Prof. Stephen Eikenberry, Cornell University. These analyses will be included in Cornell University graduate student Dae-Sik Moon's doctoral thesis.

The large-scale organization of shape processing in the ventral and dorsal pathways

PubMed Central

Culham, Jody C; Plaut, David C; Behrmann, Marlene

2017-01-01

Although shape perception is considered a function of the ventral visual pathway, evidence suggests that the dorsal pathway also derives shape-based representations. In two psychophysics and neuroimaging experiments, we characterized the response properties, topographical organization and perceptual relevance of these representations. In both pathways, shape sensitivity increased from early visual cortex to extrastriate cortex but then decreased in anterior regions. Moreover, the lateral aspect of the ventral pathway and posterior regions of the dorsal pathway were sensitive to the availability of fundamental shape properties, even for unrecognizable images. This apparent representational similarity between the posterior-dorsal and lateral-ventral regions was corroborated by a multivariate analysis. Finally, as with ventral pathway, the activation profile of posterior dorsal regions was correlated with recognition performance, suggesting a possible contribution to perception. These findings challenge a strict functional dichotomy between the pathways and suggest a more distributed model of shape processing. PMID:28980938

Article and method for making an article

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lacy, Benjamin Paul; Schick, David Edward; Kottilingam, Srikanth Chandrudu

An article and a method for making shaped cooling holes in an article are provided. The method includes the steps of providing a metal alloy powder; forming an initial layer with the metal alloy powder, the initial layer having a preselected thickness and a preselected shape, the preselected shape including at least one aperture; sequentially forming an additional layer over the initial layer with the metal alloy powder, the additional layer having a second preselected thickness and a second preselected shape, the second preselected shape including at least one aperture corresponding to the at least one aperture in the initialmore » layer; and joining the additional layer to the initial layer, forming a structure having a predetermined thickness, a predetermined shape, and at least one aperture having a predetermined profile. The structure is attached to a substrate to make the article.« less

Comparing the role of shape and texture on staging hepatic fibrosis from medical imaging

NASA Astrophysics Data System (ADS)

Zhang, Xuejun; Louie, Ryan; Liu, Brent J.; Gao, Xin; Tan, Xiaomin; Qu, Xianghe; Long, Liling

2016-03-01

The purpose of this study is to investigate the role of shape and texture in the classification of hepatic fibrosis by selecting the optimal parameters for a better Computer-aided diagnosis (CAD) system. 10 surface shape features are extracted from a standardized profile of liver; while15 texture features calculated from gray level co-occurrence matrix (GLCM) are extracted within an ROI in liver. Each combination of these input subsets is checked by using support vector machine (SVM) with leave-one-case-out method to differentiate fibrosis into two groups: normal or abnormal. The accurate rate value of all 10/15 types number of features is 66.83% by texture, while 85.74% by shape features, respectively. The irregularity of liver shape can demonstrate fibrotic grade efficiently and texture feature of CT image is not recommended to use with shape feature for interpretation of cirrhosis.

Modulation of spectral intensity, polarization and coherence of a stochastic electromagnetic beam.

PubMed

Wu, Gaofeng; Cai, Yangjian

2011-04-25

Analytical formula for the cross-spectral density matrix of a stochastic electromagnetic Gaussian Schell-model (EGSM) beam truncated by a circular phase aperture propagating in free space is derived with the help of a tensor method, which provides a reliable and fast way for studying the propagation and transformation of a truncated EGSM beam. Statistics properties, such as the spectral intensity, the degree of coherence, the degree of polarization and the polarization ellipse of a truncated EGSM beam in free space are studied numerically. The propagation factor of a truncated EGSM beam is also analyzed. Our numerical results show that we can modulate the spectral intensity, the polarization, the coherence and the propagation factor of an EGSM beam by a circular phase aperture. It is found that the phase aperture can be used to shape the beam profile of an EGSM beam and generate electromagnetic partially coherent dark hollow or flat-topped beam, which is useful in some applications, such as optical trapping, material processing, free-space optical communications.

Development of a new virtual diagnostic for V3FIT

NASA Astrophysics Data System (ADS)

Trevisan, G. L.; Cianciosa, M. R.; Terranova, D.; Hanson, J. D.

2014-12-01

The determination of plasma equilibria from diagnostic information is a fundamental issue. V3FIT is a fully three-dimensional reconstruction code capable of solving the inverse problem using both magnetic and kinetic measurements. It uses VMEC as core equilibrium solver and supports both free- and fixed-boundary reconstruction approaches. In fixed-boundary mode VMEC does not use explicit information about currents in external coils, even though it has important effects on the shape of the safety factor profile. Indeed, the edge safety factor influences the reversal position in RFP plasmas, which then determines the position of the m = 0 island chain and the edge transport properties. In order to exploit such information a new virtual diagnostic has been developed, that thanks to Ampère's law relates the external current through the center of the torus to the circulation of the toroidal magnetic field on the outermost flux surface. The reconstructions that exploit the new diagnostic are indeed found to better interpret the experimental data with respect to edge physics.

Factors influencing Internet usage in older adults (65 years and above) living in rural and urban Sweden.

PubMed

Berner, Jessica; Rennemark, Mikael; Jogréus, Claes; Anderberg, Peter; Sköldunger, Anders; Wahlberg, Maria; Elmståhl, Sölve; Berglund, Johan

2015-09-01

Older adults living in rural and urban areas have shown to distinguish themselves in technology adoption; a clearer profile of their Internet use is important in order to provide better technological and health-care solutions. Older adults' Internet use was investigated across large to midsize cities and rural Sweden. The sample consisted of 7181 older adults ranging from 59 to 100 years old. Internet use was investigated with age, education, gender, household economy, cognition, living alone/or with someone and rural/urban living. Logistic regression was used. Those living in rural areas used the Internet less than their urban counterparts. Being younger and higher educated influenced Internet use; for older urban adults, these factors as well as living with someone and having good cognitive functioning were influential. Solutions are needed to avoid the exclusion of some older adults by a society that is today being shaped by the Internet. © The Author(s) 2014.

Measurement of Size-dependent Dynamic Shape Factors of Quartz Particles in Two Flow Regimes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Alexander, Jennifer M.; Bell, David M.; Imre, D.

2016-08-02

Understanding and modeling the behavior of quartz dust particles, commonly found in the atmosphere, requires knowledge of many relevant particles properties, including particle shape. This study uses a single particle mass spectrometer, a differential mobility analyzer, and an aerosol particle mass analyzer to measure quartz aerosol particles mobility, aerodynamic, and volume equivalent diameters, mass, composition, effective density, and dynamic shape factor as a function of particle size, in both the free molecular and transition flow regimes. The results clearly demonstrate that dynamic shape factors can vary significantly as a function of particle size. For the quartz samples studied here, themore » dynamic shape factors increase with size, indicating that larger particles are significantly more aspherical than smaller particles. In addition, dynamic shape factors measured in the free-molecular (χv) and transition (χt) flow regimes can be significantly different, and these differences vary with the size of the quartz particles. For quartz, χv of small (d < 200 nm) particles is 1.25, while χv of larger particles (d ~ 440 nm) is 1.6, with a continuously increasing trend with particle size. In contrast χt, of small particles starts at 1.1 increasing slowly to 1.34 for 550 nm diameter particles. The multidimensional particle characterization approach used here goes beyond determination of average properties for each size, to provide additional information about how the particle dynamic shape factor may vary even for particles with the same mass and volume equivalent diameter.« less

Analog experimental models of solidification of crystal-laden Kīlauea Iki lava lake, Hawai`i and implications for cumulate development.

NASA Astrophysics Data System (ADS)

Burnett, C. T.; Patwardhan, K.

2016-12-01

We present results from experimental models of Kīlauea Iki lava lake with the goal of reproducing the S-shaped vertical distribution profile of phenocrysts in the solidifying lava lake. In November-December 1959, lava from a two-week long eruption at the summit of Kīlauea Volcano flowed into the adjoining Kīlauea Iki crater filling it with a lake of lava approximately 640 m across and 135 m deep. The erupted picritic lava contained approximately 17 modal % olivine phenocrysts (Garcia, 2003). As the lava lake filled most of the phenocrysts sank towards the lower parts of the lake while some were captured in the upper crust. This resulted in an S-shaped vertical profile with an olivine-depleted (1-3 % olivine) upper part and an olivine-enriched (up to 40 % olivine) lower part (Helz, 1989). In our experiments, molten paraffin wax, extra-fine craft glitter, and aluminum foil pans/bowls are used as analogs for magma, olivine phenocrysts, and Kīlauea Iki pit crater respectively. A molten paraffin-glitter mixture at approximately 54°C is stirred/poured into the crater to create the lake, and then frozen. Cross-sections of the solidified lake are photographed and imported into ImageJ to analyze the final distribution of glitter particles at various depths. This distribution depends primarily upon the competition between settling rate vs. solidification time. Particle settling rate is controlled by glitter-paraffin density difference and paraffin viscosity. Solidification time varies with initial paraffin temperature, aspect ratio of the model lake, and ambient temperature. Vertical profiles of several solidified lava lake models reveal a glitter particle (phenocryst) distribution similar to the S-shaped characteristic profile recorded at Kīlauea Iki. In effect, our lava lake models recreate the dynamic process of emplacement of crystal-laden magma with subsequent settling of these crystals to produce a phenocryst-enriched layer near the bottom. A similar process occurring in intrusions formed by emplacement of one or more crystal-laden magma batches may result in the development of cumulate layers. Our experimental methods and efforts in recreating the S-shaped profile in Kīlauea Iki may be used as a starting point to model more complex cumulate intrusions. (Special thanks to Prof. Shafiul Chowdhury)

Core transport properties in JT-60U and JET identity plasmas

NASA Astrophysics Data System (ADS)

Litaudon, X.; Sakamoto, Y.; de Vries, P. C.; Salmi, A.; Tala, T.; Angioni, C.; Benkadda, S.; Beurskens, M. N. A.; Bourdelle, C.; Brix, M.; Crombé, K.; Fujita, T.; Futatani, S.; Garbet, X.; Giroud, C.; Hawkes, N. C.; Hayashi, N.; Hoang, G. T.; Hogeweij, G. M. D.; Matsunaga, G.; Nakano, T.; Oyama, N.; Parail, V.; Shinohara, K.; Suzuki, T.; Takechi, M.; Takenaga, H.; Takizuka, T.; Urano, H.; Voitsekhovitch, I.; Yoshida, M.; ITPA Transport Group; JT-60 Team; EFDA contributors, JET

2011-07-01

The paper compares the transport properties of a set of dimensionless identity experiments performed between JET and JT-60U in the advanced tokamak regime with internal transport barrier, ITB. These International Tokamak Physics Activity, ITPA, joint experiments were carried out with the same plasma shape, toroidal magnetic field ripple and dimensionless profiles as close as possible during the ITB triggering phase in terms of safety factor, normalized Larmor radius, normalized collision frequency, thermal beta, ratio of ion to electron temperatures. Similarities in the ITB triggering mechanisms and sustainment were observed when a good match was achieved of the most relevant normalized profiles except the toroidal Mach number. Similar thermal ion transport levels in the two devices have been measured in either monotonic or non-monotonic q-profiles. In contrast, differences between JET and JT-60U were observed on the electron thermal and particle confinement in reversed magnetic shear configurations. It was found that the larger shear reversal in the very centre (inside normalized radius of 0.2) of JT-60U plasmas allowed the sustainment of stronger electron density ITBs compared with JET. As a consequence of peaked density profile, the core bootstrap current density is more than five times higher in JT-60U compared with JET. Thanks to the bootstrap effect and the slightly broader neutral beam deposition, reversed magnetic shear configurations are self-sustained in JT-60U scenarios. Analyses of similarities and differences between the two devices address key questions on the validity of the usual assumptions made in ITER steady scenario modelling, e.g. a flat density profile in the core with thermal transport barrier? Such assumptions have consequences on the prediction of fusion performance, bootstrap current and on the sustainment of the scenario.

Velocity profiles and plug zones in a free surface viscoplastic flow : experimental study and comparison to shallow flow models

NASA Astrophysics Data System (ADS)

Freydier, Perrine; Chambon, Guillaume; Naaim, Mohamed

2016-04-01

Rheological studies concerning natural muddy debris flows have shown that these materials can be modelled as non-Newtonian viscoplastic fluids. These complex flows are generally represented using models based on a depth-integrated approach (Shallow Water) that take into account closure terms depending on the shape of the velocity profile. But to date, there is poor knowledge about the shape of velocity profiles and the position of the interface between sheared and unsheared regions (plug) in these flows, especially in the vicinity of the front. In this research, the internal dynamics of a free-surface viscoplastic flow down an inclined channel is investigated and compared to the predictions of a Shallow Water model based on the lubrication approximation. Experiments are conducted in an inclined channel whose bottom is constituted by an upward-moving conveyor belt with controlled velocity, which allows generating and observing gravity-driven stationary surges in the laboratory frame. Carbopol microgel has been used as a homogeneous and transparent viscoplastic fluid. High-resolution measurements of velocity field is performed through optical velocimetry techniques both in the uniform zone and within the front zone where flow thickness is variable and where recirculation takes place. Specific analyses have been developed to determine the position of the plug within the surge. Flow height is accessible through image processing and ultrasonic sensors. Sufficiently far from the front, experimental results are shown to be in good agreement with theoretical predictions regarding the velocity profiles and the flow height evolution. In the vicinity of the front, however, analysis of measured velocity profiles shows an evolution of the plug different from that predicted by lubrication approximation. Accordingly, the free surface shape also deviates from the predictions of the classical Shallow Water model. These results highlight the necessity to take into account higher-order corrective terms in Shallow Water models in order to better account for the internal dynamics of the fluid layer.

Fabricating Blazed Diffraction Gratings by X-Ray Lithography

NASA Technical Reports Server (NTRS)

Mouroulis, Pantazis; Hartley, Frank; Wilson, Daniel

2004-01-01

Gray-scale x-ray lithography is undergoing development as a technique for fabricating blazed diffraction gratings. As such, gray-scale x-ray lithography now complements such other grating-fabrication techniques as mechanical ruling, holography, ion etching, laser ablation, laser writing, and electron-beam lithography. Each of these techniques offers advantages and disadvantages for implementing specific grating designs; no single one of these techniques can satisfy the design requirements for all applications. Gray-scale x-ray lithography is expected to be advantageous for making gratings on steeper substrates than those that can be made by electron-beam lithography. This technique is not limited to sawtooth groove profiles and flat substrates: various groove profiles can be generated on arbitrarily shaped (including highly curved) substrates with the same ease as sawtooth profiles can be generated on flat substrates. Moreover, the gratings fabricated by this technique can be made free of ghosts (spurious diffraction components attributable to small spurious periodicities in the locations of grooves). The first step in gray-scale x-ray lithography is to conformally coat a substrate with a suitable photoresist. An x-ray mask (see Figure 1) is generated, placed between the substrate and a source of collimated x-rays, and scanned over the substrate so as to create a spatial modulation in the exposure of the photoresist. Development of the exposed photoresist results in a surface corrugation that corresponds to the spatial modulation and that defines the grating surface. The grating pattern is generated by scanning an appropriately shaped x-ray area mask along the substrate. The mask example of Figure 1 would generate a blazed grating profile when scanned in the perpendicular direction at constant speed, assuming the photoresist responds linearly to incident radiation. If the resist response is nonlinear, then the mask shape can be modified to account for the nonlinearity and produce a desired groove profile. An example of grating grooves generated by this technique is shown in Figure 2. A maximum relative efficiency of 88 percent has been demonstrated.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gitti, Myriam; Nulsen, Paul E. J.; David, Laurence P.

We present the results of a Chandra study of the Hydra A galaxy cluster, where a powerful active galactic nucleus (AGN) outburst created a large-scale cocoon shock. We investigated possible azimuthal variations in shock strength and shape, finding indications for a weak shock with a Mach number in the range {approx}1.2-1.3. We measured the temperature change across the shock front. However, the detection of a temperature rise in the regions immediately inside of the front is complicated by the underlying temperature profile of the cluster atmosphere. We measured the global temperature profile of the cluster up to 700 kpc, whichmore » represents the farthest measurement obtained with Chandra for this cluster. A 'plateau' in the temperature profile in the range {approx}70-150 kpc indicates the presence of cool gas, which is likely the result of uplift of material by the AGN outburst. After masking the cool filaments visible in the hardness ratio map, the plateau disappears and the temperature profile recovers a typical shape with a peak around 190 kpc, just inside the shock front. However, it is unlikely that such a temperature feature is produced by the shock as it is consistent with the general shape of the temperature profiles observed for relaxed galaxy clusters. We studied the spectral properties of the cool filaments finding evidence that {approx}10{sup 11} M{sub sun} of low-entropy material has been dredged up by the rising lobes from the central 30 kpc to the observed current position of 75-150 kpc. The energy required to lift the cool gas is {approx}> 2.2 x 10{sup 60} erg, which is comparable to the work required to inflate the cavities and is {approx}25% of the total energy of the large-scale shock. Our results show that the AGN feedback in Hydra A is acting not only by directly heating the gas, but also by removing a substantial amount of potential fuel for the supermassive black hole.« less

To the theory of high-power gyrotrons with uptapered resonators

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dumbrajs, O.; Nusinovich, G. S.

In high-power gyrotrons it is desirable to combine an optimal resonator length with the optimal value of the resonator quality factor. In resonators with the constant radius of the central part, the possibilities of this combination are limited because the quality factor of the resonator sharply increases with its length. Therefore the attempts to increase the length for maximizing the efficiency leads to such increase in the quality factor which makes the optimal current too small. Resonators with slightly uptapered profiles offer more flexibility in this regard. In such resonators, one can separate optimization of the interaction length from optimizationmore » of the quality factor because the quality factor determined by diffractive losses can be reduced by increasing the angle of uptapering. In the present paper, these issues are analyzed by studying as a typical high-power 17 GHz gyrotron which is currently under development in Europe for ITER (http://en.wikipedia.org/wiki/ITER). The effect of a slight uptapering of the resonator wall on the efficiency enhancement and the purity of the radiation spectrum in the process of the gyrotron start-up and power modulation are studied. Results show that optimal modification of the shape of a slightly uptapered resonator may result in increasing the gyrotron power from 1052 to 1360 kW.« less

SLA Developmental Stages and Teachers' Assessment of Written French: Exploring Direkt Profil as a Diagnostic Assessment Tool

ERIC Educational Resources Information Center

Granfeldt, Jonas; Ågren, Malin

2014-01-01

One core area of research in Second Language Acquisition is the identification and definition of developmental stages in different L2s. For L2 French, Bartning and Schlyter (2004) presented a model of six morphosyntactic stages of development in the shape of grammatical profiles. The model formed the basis for the computer program Direkt Profil…

A Phenomenological Exploration of Black Male Law Enforcement Officers' Perspectives of Racial Profiling and Their Law Enforcement Career Exploration and Commitment

ERIC Educational Resources Information Center

Salters, Gregory A.

2013-01-01

This phenomenological study explored Black male law enforcement officers' perspectives of how racial profiling shaped their decisions to explore and commit to a law enforcement career. Criterion and snow ball sampling was used to obtain the 17 participants for this study. Super's (1990) archway model was used as the theoretical…

Laser one-dimensional range profile and the laser two-dimensional range profile of cylinders

NASA Astrophysics Data System (ADS)

Gong, Yanjun; Wang, Mingjun; Gong, Lei

2015-10-01

Laser one-dimensional range profile, that is scattering power from pulse laser scattering of target, is a radar imaging technology. The laser two-dimensional range profile is two-dimensional scattering imaging of pulse laser of target. Laser one-dimensional range profile and laser two-dimensional range profile are called laser range profile(LRP). The laser range profile can reflect the characteristics of the target shape and surface material. These techniques were motivated by applications of laser radar to target discrimination in ballistic missile defense. The radar equation of pulse laser is given in this paper. This paper demonstrates the analytical model of laser range profile of cylinder based on the radar equation of the pulse laser. Simulations results of laser one-dimensional range profiles of some cylinders are given. Laser range profiles of cylinder, whose surface material with diffuse lambertian reflectance, is given in this paper. Laser range profiles of different pulse width of cylinder are given in this paper. The influences of geometric parameters, pulse width, attitude on the range profiles are analyzed.

A parametric analysis of visual approaches for helicopters

NASA Technical Reports Server (NTRS)

Moen, G. C.; Dicarlo, D. J.; Yenni, K. R.

1976-01-01

A flight investigation was conducted to determine the characteristic shapes of the altitude, ground speed, and deceleration profiles of visual approaches for helicopters. Two hundred thirty-six visual approaches were flown from nine sets of initial conditions with four types of helicopters. Mathematical relationships were developed that describe the characteristic visual deceleration profiles. These mathematical relationships were expanded to develop equations which define the corresponding nominal ground speed, pitch attitude, pitch rate, and pitch acceleration profiles. Results are applicable to improved helicopter handling qualities in terminal area operations.

Aromaticity Parameters in Asphalt Binders Calculated From Profile Fitting X-ray Line Spectra Using Pearson VII and Pseudo-Voigt Functions

NASA Astrophysics Data System (ADS)

Shirokoff, J.; Lewis, J. Courtenay

2010-10-01

The aromaticity and crystallite parameters in asphalt binders are calculated from data obtained after profile fitting x-ray line spectra using Pearson VII and pseudo-Voigt functions. The results are presented and discussed in terms of the peak profile fit parameters used, peak deconvolution procedure, and differences in calculated values that can arise owing to peak shape and additional peaks present in the pattern. These results have implications concerning the evaluation and performance of asphalt binders used in highways and road applications.

Nanosatellite Maneuver Planning for Point Cloud Generation With a Rangefinder

DTIC Science & Technology

2015-06-05

aided active vision systems [11], dense stereo [12], and TriDAR [13]. However, these systems are unsuitable for a nanosatellite system from power, size...command profiles as well as improving the fidelity of gap detection with better filtering methods for background objects . For example, attitude...application of a single beam laser rangefinder (LRF) to point cloud generation, shape detection , and shape reconstruction for a space-based space

Hair Receptor Sensitivity to Changes in Laminar Boundary Layer Shape (Postprint)

DTIC Science & Technology

2010-02-01

copyright owner. Biologists have shown that bat wings contain distributed arrays of flow -sensitive hair receptors. The hair receptors are hypothesized...specialization of hair-like structures for the detection of changes in boundary layer velocity profiles (shapes). A quasi-steady model that relates the flow ...Mechanoreceptor, Artificial Hair Sensor, Medium Flow Sensor UNCLAS UNCLAS UNCLAS UL 11 Benjamin T. Dickinson 850-883-2645 Reset IOP PUBLISHING

How exponential are FREDs?

NASA Astrophysics Data System (ADS)

Schaefer, Bradley E.; Dyson, Samuel E.

1996-08-01

A common Gamma-Ray Burst-light curve shape is the ``FRED'' or ``fast-rise exponential-decay.'' But how exponential is the tail? Are they merely decaying with some smoothly decreasing decline rate, or is the functional form an exponential to within the uncertainties? If the shape really is an exponential, then it would be reasonable to assign some physically significant time scale to the burst. That is, there would have to be some specific mechanism that produces the characteristic decay profile. So if an exponential is found, then we will know that the decay light curve profile is governed by one mechanism (at least for simple FREDs) instead of by complex/multiple mechanisms. As such, a specific number amenable to theory can be derived for each FRED. We report on the fitting of exponentials (and two other shapes) to the tails of ten bright BATSE bursts. The BATSE trigger numbers are 105, 257, 451, 907, 1406, 1578, 1883, 1885, 1989, and 2193. Our technique was to perform a least square fit to the tail from some time after peak until the light curve approaches background. We find that most FREDs are not exponentials, although a few come close. But since the other candidate shapes come close just as often, we conclude that the FREDs are misnamed.

Individuality and togetherness in joint improvised motion.

PubMed

Hart, Yuval; Noy, Lior; Feniger-Schaal, Rinat; Mayo, Avraham E; Alon, Uri

2014-01-01

Actors, dancers and musicians that improvise together report special moments of togetherness: high performance and synchrony, seemingly without a leader and a follower. Togetherness seems to conflict with individuality- the idiosyncratic character of each person's performance. To understand the relation of individuality and togetherness, we employed the mirror game paradigm in which two players are asked to mirror each other and create interesting synchronized motion, with and without a designated leader. The mirror game enables quantitative characterization of moments of togetherness in which complex motion is generated with high synchrony. We find that each person as a leader does basic strokes of motion with a characteristic signature, in terms of the shape of their velocity profile between two stopping events. In moments of togetherness both players change their signature to a universal stroke shape. This universal velocity profile resembles a half-period of a sine wave, and is therefore symmetric and maximally smooth. Thus, instead of converging to an intermediate motion signature, or having one player dominate, players seem to shift their basic motion signatures to a shape that is altogether different from their individually preferred shapes; the resulting motion may be easier to predict and to agree on. The players then build complex motion by using such smooth elementary strokes.

Individuality and Togetherness in Joint Improvised Motion

PubMed Central

Feniger-Schaal, Rinat; Mayo, Avraham E.; Alon, Uri

2014-01-01

Actors, dancers and musicians that improvise together report special moments of togetherness: high performance and synchrony, seemingly without a leader and a follower. Togetherness seems to conflict with individuality- the idiosyncratic character of each person's performance. To understand the relation of individuality and togetherness, we employed the mirror game paradigm in which two players are asked to mirror each other and create interesting synchronized motion, with and without a designated leader. The mirror game enables quantitative characterization of moments of togetherness in which complex motion is generated with high synchrony. We find that each person as a leader does basic strokes of motion with a characteristic signature, in terms of the shape of their velocity profile between two stopping events. In moments of togetherness both players change their signature to a universal stroke shape. This universal velocity profile resembles a half-period of a sine wave, and is therefore symmetric and maximally smooth. Thus, instead of converging to an intermediate motion signature, or having one player dominate, players seem to shift their basic motion signatures to a shape that is altogether different from their individually preferred shapes; the resulting motion may be easier to predict and to agree on. The players then build complex motion by using such smooth elementary strokes. PMID:24533054

Method of manufacturing large dish reflectors for a solar concentrator apparatus

DOEpatents

Angel, Roger P [Tucson, AZ; Olbert, Blain H [Tucson, AZ

2011-12-27

A method of manufacturing monolithic glass reflectors for concentrating sunlight in a solar energy system is disclosed. The method of manufacturing allows large monolithic glass reflectors to be made from float glass in order to realize significant cost savings on the total system cost for a solar energy system. The method of manufacture includes steps of heating a sheet of float glass positioned over a concave mold until the sheet of glass sags and stretches to conform to the shape of the mold. The edges of the dish-shaped glass are rolled for structural stiffening around the periphery. The dish-shaped glass is then silvered to create a dish-shaped mirror that reflects solar radiation to a focus. The surface of the mold that contacts the float glass preferably has a grooved surface profile comprising a plurality of cusps and concave valleys. This grooved profile minimizes the contact area and marring of the specular glass surface, reduces parasitic heat transfer into the mold and increases mold lifetime. The disclosed method of manufacture is capable of high production rates sufficiently fast to accommodate the output of a conventional float glass production line so that monolithic glass reflectors can be produced as quickly as a float glass production can make sheets of float glass to be used in the process.

Temperature dependent evolution of wrinkled single-crystal silicon ribbons on shape memory polymers.

PubMed

Wang, Yu; Yu, Kai; Qi, H Jerry; Xiao, Jianliang

2017-10-25

Shape memory polymers (SMPs) can remember two or more distinct shapes, and thus can have a lot of potential applications. This paper presents combined experimental and theoretical studies on the wrinkling of single-crystal Si ribbons on SMPs and the temperature dependent evolution. Using the shape memory effect of heat responsive SMPs, this study provides a method to build wavy forms of single-crystal silicon thin films on top of SMP substrates. Silicon ribbons obtained from a Si-on-insulator (SOI) wafer are released and transferred onto the surface of programmed SMPs. Then such bilayer systems are recovered at different temperatures, yielding well-defined, wavy profiles of Si ribbons. The wavy profiles are shown to evolve with time, and the evolution behavior strongly depends on the recovery temperature. At relatively low recovery temperatures, both wrinkle wavelength and amplitude increase with time as evolution progresses. Finite element analysis (FEA) accounting for the thermomechanical behavior of SMPs is conducted to study the wrinkling of Si ribbons on SMPs, which shows good agreement with experiment. Merging of wrinkles is observed in FEA, which could explain the increase of wrinkle wavelength observed in the experiment. This study can have important implications for smart stretchable electronics, wrinkling mechanics, stimuli-responsive surface engineering, and advanced manufacturing.

Effective spring stiffness for a periodic array of interacting coplanar penny-shaped cracks at an interface between two dissimilar isotropic materials

PubMed Central

Lekesiz, Huseyin; Katsube, Noriko; Rokhlin, Stanislav I.; Seghi, Robert R.

2013-01-01

An effective spring stiffness approximation is proposed for a hexagonal array of coplanar penny shaped cracks located at the interface between two dissimilar solids. The approximation is based on the factorization of the solution on the material dissimilarity factor, the crack interaction factor and the effective spring stiffness solution for non-interacting cracks in a homogeneous material. Such factorization is exact and was validated for 2D collinear cracks between two dissimilar solids. The crack interaction factor is obtained using a recently developed model for stress intensity factors for an array of coplanar penny shaped cracks in a homogeneous material; also the material dissimilarity function recently obtained for non-interacting penny shaped crack at the interface between two dissimilar materials is employed. The obtained solution is useful for an assessment by ultrasonic measurements of the interface stiffness in bonded structures for monitoring the interfacial microdamage growth due to mechanical loading and environmental factors. PMID:27175036

Effective spring stiffness for a periodic array of interacting coplanar penny-shaped cracks at an interface between two dissimilar isotropic materials.

PubMed

Lekesiz, Huseyin; Katsube, Noriko; Rokhlin, Stanislav I; Seghi, Robert R

2013-08-15

An effective spring stiffness approximation is proposed for a hexagonal array of coplanar penny shaped cracks located at the interface between two dissimilar solids. The approximation is based on the factorization of the solution on the material dissimilarity factor, the crack interaction factor and the effective spring stiffness solution for non-interacting cracks in a homogeneous material. Such factorization is exact and was validated for 2D collinear cracks between two dissimilar solids. The crack interaction factor is obtained using a recently developed model for stress intensity factors for an array of coplanar penny shaped cracks in a homogeneous material; also the material dissimilarity function recently obtained for non-interacting penny shaped crack at the interface between two dissimilar materials is employed. The obtained solution is useful for an assessment by ultrasonic measurements of the interface stiffness in bonded structures for monitoring the interfacial microdamage growth due to mechanical loading and environmental factors.

Profile: a computer program for displaying the geometric relationships of the responses in a factorial design

Treesearch

Stanford L. Arner

1974-01-01

One procedure in analyzing the responses to factors in an experiment is to construct profiles of the means. Profiles are plots of the sample means of each level of one factor at each level of one or more of the other factors in the experiment. The construction of these profiles and tests of hypotheses about the mean responses is called profile analysis. This paper...

Bright-dark and dark-dark solitons for the coupled cubic-quintic nonlinear Schrödinger equations in a twin-core nonlinear optical fiber

NASA Astrophysics Data System (ADS)

Yuan, Yu-Qiang; Tian, Bo; Liu, Lei; Chai, Han-Peng

2017-11-01

In this paper, we investigate the coupled cubic-quintic nonlinear Schrödinger equations, which can describe the effects of quintic nonlinearity on the ultrashort optical soliton pulse propagation in a twin-core nonlinear optical fiber. Through the Kadomtsev-Petviashvili hierarchy reduction, we present the bright-dark and dark-dark soliton solutions in terms of the Grammian for such equations. With the help of analytic and graphic analysis, head-on and overtaking elastic interactions between the two solitons are presented, as well as the bound-state solitons. Particularly, we find the inelastic interaction between the bright-dark two solitons. One of the electromagnetic fields presents the V-shape profile, while the other one presents the Y-shape profile.

TE modes of UV-laser generated waveguides in a planar polymer chip of parabolic refractive index profile

NASA Astrophysics Data System (ADS)

Shams El-Din, M. A.

2018-04-01

The UV-laser lithographic method is used for the preparation of Polymeric integrated-optical waveguides in a planar polymer chip. The waveguide samples are irradiated by an excimer laser of wavelength 248 nm with different doses and with the same fluencies. The refractive index depth profile for the waveguides, in the first zone is found to have a parabolic shape and Gaussian shape in the second one that can be determined by Mach-Zehnder interferometer. Both the mode field distribution and the effective mode indices for the first zone only are determined by making use of the theoretical mode and the experimental data. It is found that the model field distribution is strongly dependent on the refractive indices for each zone.

In vivo size and shape measurement of the human upper airway using endoscopic longrange optical coherence tomography

NASA Astrophysics Data System (ADS)

Armstrong, Julian J.; Leigh, Matthew S.; Walton, Ian D.; Zvyagin, Andrei V.; Alexandrov, Sergey A.; Schwer, Stefan; Sampson, David D.; Hillman, David R.; Eastwood, Peter R.

2003-07-01

We describe a long-range optical coherence tomography system for size and shape measurement of large hollow organs in the human body. The system employs a frequency-domain optical delay line of a configuration that enables the combination of high-speed operation with long scan range. We compare the achievable maximum delay of several delay line configurations, and identify the configurations with the greatest delay range. We demonstrate the use of one such long-range delay line in a catheter-based optical coherence tomography system and present profiles of the human upper airway and esophagus in vivo with a radial scan range of 26 millimeters. Such quantitative upper airway profiling should prove valuable in investigating the pathophysiology of airway collapse during sleep (obstructive sleep apnea).

Fast neutron-gamma discrimination on neutron emission profile measurement on JT-60U.

PubMed

Ishii, K; Shinohara, K; Ishikawa, M; Baba, M; Isobe, M; Okamoto, A; Kitajima, S; Sasao, M

2010-10-01

A digital signal processing (DSP) system is applied to stilbene scintillation detectors of the multichannel neutron emission profile monitor in JT-60U. Automatic analysis of the neutron-γ pulse shape discrimination is a key issue to diminish the processing time in the DSP system, and it has been applied using the two-dimensional (2D) map. Linear discriminant function is used to determine the dividing line between neutron events and γ-ray events on a 2D map. In order to verify the validity of the dividing line determination, the pulse shape discrimination quality is evaluated. As a result, the γ-ray contamination in most of the beam heating phase was negligible compared with the statistical error with 10 ms time resolution.

Robust, Flexible and Lightweight Dielectric Barrier Discharge Actuators Using Nanofoams/Aerogels

NASA Technical Reports Server (NTRS)

Siochi, Emilie J. (Inventor); Sauti, Godfrey (Inventor); Wilkinson, Stephen P. (Inventor); Guo, Haiquan N. (Inventor); Xu, Tian-Bing (Inventor); Meador, Mary Ann B. (Inventor)

2015-01-01

Robust, flexible, lightweight, low profile enhanced performance dielectric barrier discharge actuators (plasma actuators) based on aerogels/nanofoams with controlled pore size and size distribution as well as pore shape. The plasma actuators offer high body force as well as high force to weight ratios (thrust density). The flexibility and mechanical robustness of the actuators allows them to be shaped to conform to the surface to which they are applied. Carbon nanotube (CNT) based electrodes serve to further decrease the weight and profile of the actuators while maintaining flexibility while insulating nano-inclusions in the matrix enable tailoring of the mechanical properties. Such actuators are required for flow control in aeronautics and moving machinery such as wind turbines, noise abatement in landing gear and rotary wing aircraft and other applications.

Fast neutron-gamma discrimination on neutron emission profile measurement on JT-60U

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ishii, K.; Okamoto, A.; Kitajima, S.

2010-10-15

A digital signal processing (DSP) system is applied to stilbene scintillation detectors of the multichannel neutron emission profile monitor in JT-60U. Automatic analysis of the neutron-{gamma} pulse shape discrimination is a key issue to diminish the processing time in the DSP system, and it has been applied using the two-dimensional (2D) map. Linear discriminant function is used to determine the dividing line between neutron events and {gamma}-ray events on a 2D map. In order to verify the validity of the dividing line determination, the pulse shape discrimination quality is evaluated. As a result, the {gamma}-ray contamination in most of themore » beam heating phase was negligible compared with the statistical error with 10 ms time resolution.« less

Explosive shaped charge penetration into tuff rock

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vigil, M.G.

1988-10-01

Analysis and data for the use of Explosive Shaped Charges (ESC) to generate holes in tuff rock formation is presented. The ESCs evaluated include Conical Shaped Charges (CSC) and Explosive Formed Projectiles (EFP). The CSCs vary in size from 0.158 to 9.1 inches inside cone diameter. The EFPs were 5.0 inches in diameter. Data for projectile impact angles of 30 and 90 degrees are presented. Analytically predicted depth of penetration data generally compared favorably with experimental data. Predicted depth of penetration versus ESC standoff data and hole profile dimensions in tuff are also presented. 24 refs., 45 figs., 6 tabs.

Active Control of Interface Shape During the Crystal Growth of Lead Bromide

NASA Technical Reports Server (NTRS)

Duval, W. M. B.; Batur, C.; Singh, N. B.

2003-01-01

A thermal model for predicting and designing the furnace temperature profile was developed and used for the crystal growth of lead bromide. The model gives the ampoule temperature as a function of the furnace temperature, thermal conductivity, heat transfer coefficients, and ampoule dimensions as variable parameters. Crystal interface curvature was derived from the model and it was compared with the predicted curvature for a particular furnace temperature and growth parameters. Large crystals of lead bromide were grown and it was observed that interface shape was in agreement with the shape predicted by this model.

Highlights of TOMS Version 9 Total Ozone Algorithm

NASA Technical Reports Server (NTRS)

Bhartia, Pawan; Haffner, David

2012-01-01

The fundamental basis of TOMS total ozone algorithm was developed some 45 years ago by Dave and Mateer. It was designed to estimate total ozone from satellite measurements of the backscattered UV radiances at few discrete wavelengths in the Huggins ozone absorption band (310-340 nm). Over the years, as the need for higher accuracy in measuring total ozone from space has increased, several improvements to the basic algorithms have been made. They include: better correction for the effects of aerosols and clouds, an improved method to account for the variation in shape of ozone profiles with season, latitude, and total ozone, and a multi-wavelength correction for remaining profile shape errors. These improvements have made it possible to retrieve total ozone with just 3 spectral channels of moderate spectral resolution (approx. 1 nm) with accuracy comparable to state-of-the-art spectral fitting algorithms like DOAS that require high spectral resolution measurements at large number of wavelengths. One of the deficiencies of the TOMS algorithm has been that it doesn't provide an error estimate. This is a particular problem in high latitudes when the profile shape errors become significant and vary with latitude, season, total ozone, and instrument viewing geometry. The primary objective of the TOMS V9 algorithm is to account for these effects in estimating the error bars. This is done by a straightforward implementation of the Rodgers optimum estimation method using a priori ozone profiles and their error covariances matrices constructed using Aura MLS and ozonesonde data. The algorithm produces a vertical ozone profile that contains 1-2.5 pieces of information (degrees of freedom of signal) depending upon solar zenith angle (SZA). The profile is integrated to obtain the total column. We provide information that shows the altitude range in which the profile is best determined by the measurements. One can use this information in data assimilation and analysis. A side benefit of this algorithm is that it is considerably simpler than the present algorithm that uses a database of 1512 profiles to retrieve total ozone. These profiles are tedious to construct and modify. Though conceptually similar to the SBUV V8 algorithm that was developed about a decade ago, the SBUV and TOMS V9 algorithms differ in detail. The TOMS algorithm uses 3 wavelengths to retrieve the profile while the SBUV algorithm uses 6-9 wavelengths, so TOMS provides less profile information. However both algorithms have comparable total ozone information and TOMS V9 can be easily adapted to use additional wavelengths from instruments like GOME, OMI and OMPS to provide better profile information at smaller SZAs. The other significant difference between the two algorithms is that while the SBUV algorithm has been optimized for deriving monthly zonal means by making an appropriate choice of the a priori error covariance matrix, the TOMS algorithm has been optimized for tracking short-term variability using month and latitude dependent covariance matrices.

Identifying at-risk profiles and protective factors for problem gambling: A longitudinal study across adolescence and early adulthood.

PubMed

Allami, Youssef; Vitaro, Frank; Brendgen, Mara; Carbonneau, René; Tremblay, Richard E

2018-05-01

Past studies have identified various risk and protective factors for problem gambling (PG). However, no study has examined the interplay between these factors using a combination of person-centered and variable-centered approaches embedded within a longitudinal design. The present study aimed to (a) identify distinct profiles in early adolescence based on a set of risk factors commonly associated with PG (impulsivity, depression, anxiety, drug-alcohol use, aggressiveness, and antisociality), (b) explore the difference in reported gambling problems between these profiles during midadolescence and early adulthood, and (c) identify family- and peer-related variables that could operate as protective or compensatory factors in this context. Two samples were used: (a) a population sample (N = 1,033) living in low socioeconomic-status neighborhoods and (b) a population sample (N = 3,017) representative of students attending Quebec schools. Latent profile analyses were conducted to identify at-risk profiles based on individual risk factors measured at age 12 years. Negative binomial regression models were estimated to compare profiles in terms of their reported gambling problems at ages 16 and 23. Finally, family- and peer-related variables measured at age 14 were included to test their protective or compensatory role with respect to the link between at-risk profiles and gambling problems. Four profiles were identified: well-adjusted, internalizing, externalizing, and comorbid. Compared to the well-adjusted profile, the externalizing and comorbid profiles reported more gambling problems at ages 16 and 23, but the internalizing profile did not differ significantly. Various protective and compensatory factors emerged for each profile at both time points. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

Deuterium and the Local Interstellar Medium: Properties for the Procyon and Capella Lines of Sight

NASA Technical Reports Server (NTRS)

Linsky, Jeffrey L.; Diplas, Athanassios; Wood, Brian E.; Brown, Alexander; Ayres, Thomas R.; Savage, Blair D.

1995-01-01

We present Goddard High-Resolution Spectrograph observations of the interstellar H I and D I Ly-alpha lines and the Mg II and Fe II resonance lines formed along the lines of sight toward the nearby stars Procyon (3.5 pc, l = 214 deg, b = 13 deg) and Capella (12.5 pc, l = 163 deg, b = 5 deg). New observations of Capella were obtained at orbital phase 0.80, when the radial velocities of the intrinsic Ly-alpha emission lines of each star were nearly reversed from those of the previous observations at phase 0.26. Since the intrinsic Ly-alpha line of the Capella system (the 'continuum' against which the interstellar absorption is measured) has different shapes at phases 0.26 and 0.80, we can derive both the intrinsic stellar profiles and the interstellar absorption lines more precisely by jointly analyzing the two data sets. For the analysis of the Procyon line of sight, we first assumed that the intrinsic Ly-alpha line profile is a broadened solar profile, but this assumption does not lead to a good fit to the observed D I line profile for any value of D/H. We then assumed that (D/H)(sub LISM) = 1.6 x 10(exp -5), the same value as for the Capella line of sight, and we modified the broadened solar profile to achieve agreement between the simulated and observed line profiles. The resulting asymmetric intrinsic stellar line profile is consistent with the shapes of the scaled Mg II line profiles. We believe therefore that the Procyon data are consistent with (D/H)(sub LISM) = 1.6 x 10(exp -5), but the uncertainty in the intrinsic Ly-alpha emission-line profile does not permit us to conclude that the D/H ratio is constant in the local interstellar medium (LISM). The temperature and turbulence in the Procyon line of sight are T = 6900 +/- 80 (+/- 300 systematic error) K and zeta = 1.21 +/- 0.27 km/s. These properties are similar to those of Capella, except that the gas toward Procyon is divided into two velocity components separated by 2.6 km/s and the Procyon line of sight has a mean neutral hydrogen density that is a factor of 2.4 larger than that of the Capella line of sight. This suggests that the first 5.3 pc along the Capella line of sight lies within the local cloud and the remaining 7.2 pc lies in the hot gas surrounding the local cloud. We propose that n(H I) = 0.1065 +/- 0.0028 cm(exp -2) be adopted for the neutral hydrogen density within the local cloud and that zeta = 1.21 +/- 0.27 km/s be adopted for the nonthermal motions. The existence of different second velocity components toward the nearby stars Procyon and Sirius provides the first glimpse of a turbulent cloudlet boundary layer between the local cloud and the surrounding hot interstellar gas.

Subcortical shape and volume abnormalities in an elderly HIV+ cohort

NASA Astrophysics Data System (ADS)

Wade, Benjamin S. C.; Valcour, Victor; Busovaca, Edgar; Esmaeili-Firidouni, Pardis; Joshi, Shantanu H.; Wang, Yalin; Thompson, Paul M.

2015-03-01

Over 50% of HIV+ individuals show significant impairment in psychomotor functioning, processing speed, working memory and attention [1, 2]. Patients receiving combination antiretroviral therapy may still have subcortical atrophy, but the profile of HIV-associated brain changes is poorly understood. With parametric surface-based shape analyses, we mapped the 3D profile of subcortical morphometry in 63 elderly HIV+ subjects (4 female; age=65.35 ± 2.21) and 31 uninfected elderly controls (2 female; age=64.68 ± 4.57) scanned with MRI as part of a San Francisco Bay Area study of elderly people with HIV. We also investigated whether morphometry was associated with nadir CD4+ (T-cell) counts, viral load and illness duration among HIV+ participants. FreeSurfer was used to segment the thalamus, caudate, putamen, pallidum, hippocampus, amygdala, accumbens, brainstem, callosum and ventricles from brain MRI scans. To study subcortical shape, we analyzed: (1) the Jacobian determinant (JD) indexed over structures' surface coordinates and (2) radial distances (RD) of structure surfaces from a medial curve. A JD less than 1 reflects regional tissue atrophy and greater than 1 reflects expansion. The volumes of several subcortical regions were found to be associated with HIV status. No regional volumes showed detectable associations with CD4 counts, viral load or illness duration. The shapes of numerous subcortical regions were significantly linked to HIV status, detectability of viral RNA and illness duration. Our results show subcortical brain differences in HIV+ subjects in both shape and volumetric domains.

Three-Dimensional Biologically Relevant Spectrum (BRS-3D): Shape Similarity Profile Based on PDB Ligands as Molecular Descriptors.

PubMed

Hu, Ben; Kuang, Zheng-Kun; Feng, Shi-Yu; Wang, Dong; He, Song-Bing; Kong, De-Xin

2016-11-17

The crystallized ligands in the Protein Data Bank (PDB) can be treated as the inverse shapes of the active sites of corresponding proteins. Therefore, the shape similarity between a molecule and PDB ligands indicated the possibility of the molecule to bind with the targets. In this paper, we proposed a shape similarity profile that can be used as a molecular descriptor for ligand-based virtual screening. First, through three-dimensional (3D) structural clustering, 300 diverse ligands were extracted from the druggable protein-ligand database, sc-PDB. Then, each of the molecules under scrutiny was flexibly superimposed onto the 300 ligands. Superimpositions were scored by shape overlap and property similarity, producing a 300 dimensional similarity array termed the "Three-Dimensional Biologically Relevant Spectrum (BRS-3D)". Finally, quantitative or discriminant models were developed with the 300 dimensional descriptor using machine learning methods (support vector machine). The effectiveness of this approach was evaluated using 42 benchmark data sets from the G protein-coupled receptor (GPCR) ligand library and the GPCR decoy database (GLL/GDD). We compared the performance of BRS-3D with other 2D and 3D state-of-the-art molecular descriptors. The results showed that models built with BRS-3D performed best for most GLL/GDD data sets. We also applied BRS-3D in histone deacetylase 1 inhibitors screening and GPCR subtype selectivity prediction. The advantages and disadvantages of this approach are discussed.