User's guide for a computer program for calculating the zero-lift wave drag of complex aircraft configurations

NASA Technical Reports Server (NTRS)

Craidon, C. B.

1983-01-01

A computer program was developed to extend the geometry input capabilities of previous versions of a supersonic zero lift wave drag computer program. The arbitrary geometry input description is flexible enough to describe almost any complex aircraft concept, so that highly accurate wave drag analysis can now be performed because complex geometries can be represented accurately and do not have to be modified to meet the requirements of a restricted input format.

Complexity, Diversity and Ambiguity in Teaching and Teacher Education: Practical Wisdom, Pedagogical Fitness and Tact of Teaching

ERIC Educational Resources Information Center

Riedler, Martina; Eryaman, Mustafa Yunus

2016-01-01

There is consensus in the literature that teacher education programs exhibit the characteristics of complex systems. These characteristics of teacher education programs as complex systems challenges the conventional, teacher-directed/ textbook-based positivist approaches in teacher education literature which has tried to reduce the complexities…

Matrix management in hospitals: testing theories of matrix structure and development.

PubMed

Burns, L R

1989-09-01

A study of 315 hospitals with matrix management programs was used to test several hypotheses concerning matrix management advanced by earlier theorists. The study verifies that matrix management involves several distinctive elements that can be scaled to form increasingly complex types of lateral coordinative devices. The scalability of these elements is evident only cross-sectionally. The results show that matrix complexity is not an outcome of program age, nor does matrix complexity at the time of implementation appear to influence program survival. Matrix complexity, finally, is not determined by the organization's task diversity and uncertainty. The results suggest several modifications in prevailing theories of matrix organization.

Automated Planning Enables Complex Protocols on Liquid-Handling Robots.

PubMed

Whitehead, Ellis; Rudolf, Fabian; Kaltenbach, Hans-Michael; Stelling, Jörg

2018-03-16

Robotic automation in synthetic biology is especially relevant for liquid handling to facilitate complex experiments. However, research tasks that are not highly standardized are still rarely automated in practice. Two main reasons for this are the substantial investments required to translate molecular biological protocols into robot programs, and the fact that the resulting programs are often too specific to be easily reused and shared. Recent developments of standardized protocols and dedicated programming languages for liquid-handling operations addressed some aspects of ease-of-use and portability of protocols. However, either they focus on simplicity, at the expense of enabling complex protocols, or they entail detailed programming, with corresponding skills and efforts required from the users. To reconcile these trade-offs, we developed Roboliq, a software system that uses artificial intelligence (AI) methods to integrate (i) generic formal, yet intuitive, protocol descriptions, (ii) complete, but usually hidden, programming capabilities, and (iii) user-system interactions to automatically generate executable, optimized robot programs. Roboliq also enables high-level specifications of complex tasks with conditional execution. To demonstrate the system's benefits for experiments that are difficult to perform manually because of their complexity, duration, or time-critical nature, we present three proof-of-principle applications for the reproducible, quantitative characterization of GFP variants.

Visualizing the Complex Process for Deep Learning with an Authentic Programming Project

ERIC Educational Resources Information Center

Peng, Jun; Wang, Minhong; Sampson, Demetrios

2017-01-01

Project-based learning (PjBL) has been increasingly used to connect abstract knowledge and authentic tasks in educational practice, including computer programming education. Despite its promising effects on improving learning in multiple aspects, PjBL remains a struggle due to its complexity. Completing an authentic programming project involves a…

The Effect of a Complex Training Program on Skating Abilities in Ice Hockey Players

PubMed Central

Lee, Changyoung; Lee, Sookyung; Yoo, Jaehyun

2014-01-01

[Purpose] Little data exist on systemic training programs to improve skating abilities in ice hockey players. The purpose of this study was to evaluate the effectiveness of a complex training program on skating abilities in ice hockey players. [Methods] Ten male ice hockey players (training group) that engaged in 12 weeks of complex training and skating training and ten male players (control group) that only participated in 12 weeks of skating training completed on-ice skating tests including a 5 time 18 meters shuttle, t-test, Rink dash 5 times, and line drill before, during, and the training. [Results] Significant group-by-time interactions were found in all skating ability tests. [Conclusion] The complex training program intervention for 12 weeks improved their skating abilities of the ice hockey players. PMID:24764628

Complex Burn Region Module (CBRM) update

NASA Technical Reports Server (NTRS)

Adams, Carl L.; Jenkins, Billy

1991-01-01

Presented here is a Complex Burn Region Module (CBRM) update for the Solid Rocket Internal Ballistics Module (SRIBM) Program for the Advanced Solid Rocket Motor (ASRM) design/performance assessments. The goal was to develop an improved version of the solid rocket internal ballistics module program that contains a diversified complex region model for motor grain design, performance prediction, and evaluation.

Precedent approach to the formation of programs for cyclic objects control

NASA Astrophysics Data System (ADS)

Kulakov, S. M.; Trofimov, V. B.; Dobrynin, A. S.; Taraborina, E. N.

2018-05-01

The idea and procedure for formalizing the precedent method of formation of complex control solutions (complex control programs) is discussed with respect to technological or organizational objects, the operation of which is organized cyclically. A typical functional structure of the system of precedent control by complex technological unit is developed, including a subsystem of retrospective optimization of actually implemented control programs. As an example, the problem of constructing replaceable planograms for the operation of the link of a heading-and-winning machine on the basis of precedents is considered.

Developing Leadership for Increasing Complexity: A Review of Online Graduate Leadership Programs

ERIC Educational Resources Information Center

Winton, Steven L.; Palmer, Sarah; Hughes, Patrick J.

2018-01-01

Leadership education must evolve to keep pace with the growing recognition that effective leadership happens in a complex environment and is as much a systemic variable as a personal one. As part of a program review process, a graduate leadership program at a private Midwestern university conducted a qualitative review of 18 online graduate…

Has First-Grade Core Reading Program Text Complexity Changed across Six Decades?

ERIC Educational Resources Information Center

Fitzgerald, Jill; Elmore, Jeff; Relyea, Jackie Eunjung; Hiebert, Elfrieda H.; Stenner, A. Jackson

2016-01-01

The purpose of the study was to address possible text complexity shifts across the past six decades for a continually best-selling first-grade core reading program. The anthologies of one publisher's seven first-grade core reading programs were examined using computer-based analytics, dating from 1962 to 2013. Variables were Overall Text…

Complex System Governance for Acquisition

DTIC Science & Technology

2016-04-30

2014, September–October). Cybersecurity challenges for program managers . Defense AT&L. Naphade, M., Banavar, G., Harrison, C., Paraszczak, J...the Acquisition Research Program of the Graduate School of Business & Public Policy at the Naval Postgraduate School. To request defense...Dickmann, Vice President, Sonalysts Inc. A Complex Systems Perspective of Risk Mitigation and Modeling in Development and Acquisition Programs Roshanak

A Program Complexity Metric Based on Variable Usage for Algorithmic Thinking Education of Novice Learners

ERIC Educational Resources Information Center

Fuwa, Minori; Kayama, Mizue; Kunimune, Hisayoshi; Hashimoto, Masami; Asano, David K.

2015-01-01

We have explored educational methods for algorithmic thinking for novices and implemented a block programming editor and a simple learning management system. In this paper, we propose a program/algorithm complexity metric specified for novice learners. This metric is based on the variable usage in arithmetic and relational formulas in learner's…

Data systems and computer science: Software Engineering Program

NASA Technical Reports Server (NTRS)

Zygielbaum, Arthur I.

1991-01-01

An external review of the Integrated Technology Plan for the Civil Space Program is presented. This review is specifically concerned with the Software Engineering Program. The goals of the Software Engineering Program are as follows: (1) improve NASA's ability to manage development, operation, and maintenance of complex software systems; (2) decrease NASA's cost and risk in engineering complex software systems; and (3) provide technology to assure safety and reliability of software in mission critical applications.

Improving International Marketing Programs to Reflect Global Complexity and Risk: Curriculum Drivers and Constraints

ERIC Educational Resources Information Center

Vos, Lynn

2013-01-01

This article looks at the curriculum redesign of a master's-level program in international marketing from a UK perspective. In order to ensure that the program would be more fit-for-purpose for future managers working under conditions of complexity, uncertainty, and within regimes often very different from the home market, the team began the…

Aerial photo shows RLV complex at KSC

NASA Technical Reports Server (NTRS)

2000-01-01

This closeup photo shows the Reusable Launch Vehicle (RLV) Support Complex at Kennedy Space Center. At right is a multi- purpose hangar and to the left is a building for related ground support equipment and administrative/ technical support. The complex is situated at the Shuttle Landing Facility. The RLV complex will be available to accommodate the Space Shuttle; the X-34 RLV technology demonstrator; the L-1011 carrier aircraft for Pegasus and X-34; and other RLV and X-vehicle programs. The complex is jointly funded by the Spaceport Florida Authority, NASA's Space Shuttle Program and KSC.

Algorithms and programs complex for solving inverse problems of artificial Earth satellite dynamics with using parallel computation. (Russian Title: Программно-математическое обеспечение для решения обратных задач динамики ИСЗ с использованием параллельных вычислений )

NASA Astrophysics Data System (ADS)

Chuvashov, I. N.

2011-07-01

In this paper complex of algorithms and programs for solving inverse problems of artificial earth satellite dynamics is described. Complex has been intended for satellite orbit improvement, calculation of motion model parameters and etc. Programs complex has been worked up for cluster "Skiff Cyberia". Results of numerical experiments obtained by using new complex in common the program "Numerical model of the system artificial satellites motion" is presented in this paper.

PROGRAM-ORIENTED INFORMATION--A MANAGEMENT SYSTEMS COMPLEX FOR STATE EDUCATION AGENCIES. PART II, MANUAL OF ACCOUNTING AND RELATED FINANCIAL PROCEDURES.

ERIC Educational Resources Information Center

FRIEDMAN, BURTON DEAN; AND OTHERS

THIS DOCUMENT IS THE SECOND PART OF A REPORT, PROGRAM-ORIENTED INFORMATION--A MANAGEMENT SYSTEMS COMPLEX FOR STATE EDUCATION AGENCIES. PART 1, EA 001 170, SUBTITLED "ANALYSIS AND PROPOSALS," CONTAINS AN OUTLINE OF THE NEED FOR A MANAGEMENT SYSTEMS COMPLEX WITHIN EACH STATE EDUCATION AGENCY. THIS DOCUMENT IS A MANUAL PRESENTING THE…

Comparing short-term complex and compound training programs on vertical jump height and power output.

PubMed

Mihalik, Jason P; Libby, Jeremiah J; Battaglini, Claudio L; McMurray, Robert G

2008-01-01

The purpose of this study was to determine whether there were differences in vertical jump height and lower body power production gains between complex and compound training programs. A secondary purpose was to determine whether differences in gains were observed at a faster rate between complex and compound training programs. Thirty-one college-aged club volleyball players (11 men and 20 women) were assigned into either a complex training group or a compound training group based on gender and pre-training performance measures. Both groups trained twice per week for 4 weeks. Work was equated between the 2 groups. Complex training alternated between resistance and plyometric exercises on each training day; whereas, compound training consisted of resistance training on one day and plyometric training on the other. Our analyses showed significant improvements in vertical jump height in both training groups after only 3 weeks of training (P < 0.0001); vertical jump height increased by approximately 5% and 9% in the complex and compound training groups, respectively. However, neither group improved significantly better than the other, nor did either group experience faster gains in vertical leap or power output. The results of this study suggest that performing a minimum of 3 weeks of either complex or compound training is effective for improving vertical jump height and power output; thus, coaches should choose the program which best suits their training schedules.

KSC-00pp0725

NASA Image and Video Library

2000-06-02

This closeup photo shows the Reusable Launch Vehicle (RLV) Support Complex at Kennedy Space Center. At right is a multi-purpose hangar and to the left is a building for related ground support equipment and administrative/ technical support. The complex is situated at the Shuttle Landing Facility. The RLV complex will be available to accommodate the Space Shuttle; the X-34 RLV technology demonstrator; the L-1011 carrier aircraft for Pegasus and X-34; and other RLV and X-vehicle programs. The complex is jointly funded by the Spaceport Florida Authority, NASA’s Space Shuttle Program and KSC

KSC00pp0725

NASA Image and Video Library

2000-06-02

This closeup photo shows the Reusable Launch Vehicle (RLV) Support Complex at Kennedy Space Center. At right is a multi-purpose hangar and to the left is a building for related ground support equipment and administrative/ technical support. The complex is situated at the Shuttle Landing Facility. The RLV complex will be available to accommodate the Space Shuttle; the X-34 RLV technology demonstrator; the L-1011 carrier aircraft for Pegasus and X-34; and other RLV and X-vehicle programs. The complex is jointly funded by the Spaceport Florida Authority, NASA’s Space Shuttle Program and KSC

Aerial photo shows RLV complex at KSC

NASA Technical Reports Server (NTRS)

2000-01-01

In the foreground of this aerial photo is the Reusable Launch Vehicle (RLV) Support Complex at Kennedy Space Center. At right is a multi-purpose hangar and to its left is a building for related ground support equipment and administrative/ technical support. The complex is situated at the Shuttle Landing Facility (center). At the upper left is the runway. The RLV complex will be available to accommodate the Space Shuttle; the X-34 RLV technology demonstrator; the L-1011 carrier aircraft for Pegasus and X-34; and other RLV and X-vehicle programs. The complex is jointly funded by the Spaceport Florida Authority, NASA's Space Shuttle Program and KSC.

Application of Intervention Mapping to the Development of a Complex Physical Therapist Intervention.

PubMed

Jones, Taryn M; Dear, Blake F; Hush, Julia M; Titov, Nickolai; Dean, Catherine M

2016-12-01

Physical therapist interventions, such as those designed to change physical activity behavior, are often complex and multifaceted. In order to facilitate rigorous evaluation and implementation of these complex interventions into clinical practice, the development process must be comprehensive, systematic, and transparent, with a sound theoretical basis. Intervention Mapping is designed to guide an iterative and problem-focused approach to the development of complex interventions. The purpose of this case report is to demonstrate the application of an Intervention Mapping approach to the development of a complex physical therapist intervention, a remote self-management program aimed at increasing physical activity after acquired brain injury. Intervention Mapping consists of 6 steps to guide the development of complex interventions: (1) needs assessment; (2) identification of outcomes, performance objectives, and change objectives; (3) selection of theory-based intervention methods and practical applications; (4) organization of methods and applications into an intervention program; (5) creation of an implementation plan; and (6) generation of an evaluation plan. The rationale and detailed description of this process are presented using an example of the development of a novel and complex physical therapist intervention, myMoves-a program designed to help individuals with an acquired brain injury to change their physical activity behavior. The Intervention Mapping framework may be useful in the development of complex physical therapist interventions, ensuring the development is comprehensive, systematic, and thorough, with a sound theoretical basis. This process facilitates translation into clinical practice and allows for greater confidence and transparency when the program efficacy is investigated. © 2016 American Physical Therapy Association.

Hospital graduate social work field work programs: a study in New York City.

PubMed

Showers, N

1990-02-01

Twenty-seven hospital field work programs in New York City were studied. Questionnaires were administered to program coordinators and 238 graduate social work students participating in study programs. High degrees of program structural complexity and variation were found, indicating a state of art well beyond that described in the general field work literature. High rates of student satisfaction with learning, field instructors, programs, and the overall field work experience found suggest that the complexity of study programs may be more effective than traditional field work models. Statistically nonsignificant study findings indicate areas in which hospital social work departments may develop field work programs consistent with shifting organizational needs, without undue risk to educational effectiveness. Statistically significant findings suggest areas in which inflexibility in program design may be more beneficial in the diagnostic related groups era.

A code for analysis of the fine structure in near-rigid weakly-bonded open-shell complexes that consist of a diatomic radical in a Σ3 state and a closed-shell molecule

NASA Astrophysics Data System (ADS)

Fawzy, Wafaa M.

2010-10-01

A FORTRAN code is developed for simulation and fitting the fine structure of a planar weakly-bonded open-shell complex that consists of a diatomic radical in a Σ3 electronic state and a diatomic or a polyatomic closed-shell molecule. The program sets up the proper total Hamiltonian matrix for a given J value and takes account of electron-spin-electron-spin, electron-spin rotation interactions, and the quartic and sextic centrifugal distortion terms within the complex. Also, R-dependence of electron-spin-electron-spin and electron-spin rotation couplings are considered. The code does not take account of effects of large-amplitude internal rotation of the diatomic radical within the complex. It is assumed that the complex has a well defined equilibrium geometry so that effects of large amplitude motion are negligible. Therefore, the computer code is suitable for a near-rigid rotor. Numerical diagonalization of the matrix provides the eigenvalues and the eigenfunctions that are necessary for calculating energy levels, frequencies, relative intensities of infrared or microwave transitions, and expectation values of the quantum numbers within the complex. Goodness of all the quantum numbers, with exception of J and parity, depends on relative sizes of the product of the rotational constants and quantum numbers (i.e. BJ, CJ, and AK), electron-spin-electron-spin, and electron-spin rotation couplings, as well as the geometry of the complex. Therefore, expectation values of the quantum numbers are calculated in the eigenfunctions basis of the complex. The computational time for the least squares fits has been significantly reduced by using the Hellman-Feynman theory for calculating the derivatives. The computer code is useful for analysis of high resolution infrared and microwave spectra of a planar near-rigid weakly-bonded open-shell complex that contains a diatomic fragment in a Σ3 electronic state and a closed-shell molecule. The computer program was successfully applied to analysis and fitting the observed high resolution infrared spectra of the O 2sbnd HF/O 2sbnd DF and O 2sbnd N 2O complexes. Test input file for simulation and fitting the high resolution infrared spectrum of the O 2sbnd DF complex is provided. Program summaryProgram title: TSIG_COMP Catalogue identifier: AEGM_v1_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/AEGM_v1_0.html Program obtainable from: CPC Program Library, Queen's University, Belfast, N. Ireland Licensing provisions: Standard CPC licence, http://cpc.cs.qub.ac.uk/licence/licence.html No. of lines in distributed program, including test data, etc.: 10 030 No. of bytes in distributed program, including test data, etc.: 51 663 Distribution format: tar.gz Programming language: Fortran 90, free format Computer: SGI Origin 3400, workstations and PCs Operating system: Linux, UNIX and Windows (see Restrictions below) RAM: Case dependent Classification: 16.2 Nature of problem: TSIG_COMP calculates frequencies, relative intensities, and expectation values of the various quantum numbers and parities of bound states involved in allowed ro-vibrational transitions in semi-rigid planar weakly-bonded open-shell complexes. The complexes of interest contain a free radical in a Σ3 state and a closed-shell partner, where the electron-spin-electron-spin interaction, electron-spin rotation interaction, and centrifugal forces significantly modify the spectral patterns. To date, ab initio methods are incapable of taking these effects into account to provide accurate predictions for the ro-vibrational energy levels of the complexes of interest. In the TSIG_COMP program, the problem is solved by using the proper effective Hamiltonian and molecular basis set. Solution method: The program uses a Hamiltonian operator that takes into account vibration, end-over-end rotation, electron-spin-electron-spin and electron-spin rotation interactions as well as the various centrifugal distortion terms. The Hamiltonian operator and the molecular basis set are used to set up the Hamiltonian matrix in the inertial axis system of the complex of interest. Diagonalization of the Hamiltonian matrix provides the eigenvalues and the eigenfunctions for the bound ro-vibrational states. These eigenvalues and eigenfunctions are used to calculate frequencies and relative intensities of the allowed infrared or microwave transitions as well as expectation values of all the quantum numbers and parities of states involved in the transitions. The program employs the method of least squares fits to fit the observed frequencies to the calculated frequencies to provide the molecular parameters that determine the geometry of the complex of interest. Restrictions: The number of transitions and parameters included in the fits is limited to 80 parameters and 200 transitions. However, these numbers can be increased by adjusting dimensions of the arrays (not recommended). Running the program under MS windows is recommended for simulations of any number of transitions and for fitting a relatively small number of parameters and transitions (maximum 15 parameters and 82 transitions), for fitting larger number of parameters run time error may occur. Because spectra of weakly bonded complexes are recorded at low temperatures, in most of cases fittings can be performed under MS windows. Running time: Problem-dependent. The provided test input for Linux fits 82 transitions and 21 parameters, the actual run time is 62 minutes. The provided test input file for MS windows fits 82 transitions and 15 parameters; the actual runtime is 5 minutes.

COORDINATING, COMMUNICATING AND PERFORMING COMPLEX RESEARCH THAT IDENTIFIES VULNERABLE STREAM ECOSYSTEM IN THE MID-ATLANTIC REGION

EPA Science Inventory

The USEPA's Regional Vulnerability Assessment (ReVA) program was created to advance the scientific basis for protecting vulnerable ecosystems at a regional scale. As a first step, the ReVa program will coordinate, communicate and perform complex research that will identify vulner...

Leadership Learning for Complex Organizations

ERIC Educational Resources Information Center

Ng, F. S. David

2015-01-01

Many school leadership programs are set and delivered in specific modules or workshops in order to achieve a pre-determined set of competencies, knowledge, and skills. In addition, these programs are driven by the faculty member and the prescribed content. As Singapore schools become more complex in the roles and responsibilities to educate the…

Marr's levels and the minimalist program.

PubMed

Johnson, Mark

2017-02-01

A simple change to a cognitive system at Marr's computational level may entail complex changes at the other levels of description of the system. The implementational level complexity of a change, rather than its computational level complexity, may be more closely related to the plausibility of a discrete evolutionary event causing that change. Thus the formal complexity of a change at the computational level may not be a good guide to the plausibility of an evolutionary event introducing that change. For example, while the Minimalist Program's Merge is a simple formal operation (Berwick & Chomsky, 2016), the computational mechanisms required to implement the language it generates (e.g., to parse the language) may be considerably more complex. This has implications for the theory of grammar: theories of grammar which involve several kinds of syntactic operations may be no less evolutionarily plausible than a theory of grammar that involves only one. A deeper understanding of human language at the algorithmic and implementational levels could strengthen Minimalist Program's account of the evolution of language.

Construction continues on the RLV complex at the Shuttle Landing Facility

NASA Technical Reports Server (NTRS)

1999-01-01

At the construction site of the Reusable Launch Vehicle (RLV) complex at KSC, workers take measurements for one of the buildings. Located near the Shuttle Landing Facility, the complex will include facilities for related ground support equipment and administrative/ technical support. It will be available to accommodate the Space Shuttle; the X-34 RLV technology demonstrator; the L-1011 carrier aircraft for Pegasus and X-34; and other RLV and X-vehicle programs. The complex is jointly funded by the Spaceport Florida Authority, NASA's Space Shuttle Program and KSC. The facility will be operational in early 2000.

Construction continues on the RLV complex at the Shuttle Landing Facility

NASA Technical Reports Server (NTRS)

1999-01-01

At the construction site of the Reusable Launch Vehicle (RLV) complex at KSC, a worker takes a measurement. Located near the Shuttle Landing Facility, the complex will include facilities for related ground support equipment and administrative/ technical support. It will be available to accommodate the Space Shuttle; the X-34 RLV technology demonstrator; the L-1011 carrier aircraft for Pegasus and X-34; and other RLV and X-vehicle programs. The complex is jointly funded by the Spaceport Florida Authority, NASA's Space Shuttle Program and KSC. The facility will be operational in early 2000.

Construction continues on the RLV complex at the Shuttle Landing Facility

NASA Technical Reports Server (NTRS)

1999-01-01

Construction is under way for the X-33/X-34 hangar complex near the Shuttle Landing Facility at KSC. The Reusable Launch Vehicle (RLV) complex will include facilities for related ground support equipment and administrative/ technical support. It will be available to accommodate the Space Shuttle; the X-34 RLV technology demonstrator; the L-1011 carrier aircraft for Pegasus and X-34; and other RLV and X-vehicle programs. The complex is jointly funded by the Spaceport Florida Authority, NASA's Space Shuttle Program and KSC. The facility will be operational in early 2000.

Schools as social complex adaptive systems: a new way to understand the challenges of introducing the health promoting schools concept.

PubMed

Keshavarz, Nastaran; Nutbeam, Don; Rowling, Louise; Khavarpour, Freidoon

2010-05-01

Achieving system-wide implementation of health promotion programs in schools and sustaining both the program and its health related benefits have proved challenging. This paper reports on a qualitative study examining the implementation of health promoting schools programs in primary schools in Sydney, Australia. It draw upon insights from systems science to examine the relevance and usefulness of the concept of "complex adaptive systems" as a framework to better understand ways in which health promoting school interventions could be introduced and sustained. The primary data for the study were collected by semi-structured interviews with 26 school principals and teachers. Additional information was extracted from publicly available school management plans and annual reports. We examined the data from these sources to determine whether schools exhibit characteristics of complex adaptive systems. The results confirmed that schools do exhibit most, but not all of the characteristics of social complex adaptive systems, and exhibit significant differences with artificial and natural systems. Understanding schools as social complex adaptive systems may help to explain some of the challenges of introducing and sustaining change in schools. These insights may, in turn, lead us to adopt more sophisticated approaches to the diffusion of new programs in school systems that account for the diverse, complex and context specific nature of individual school systems. Copyright (c) 2010 Elsevier Ltd. All rights reserved.

Reduze - Feynman integral reduction in C++

NASA Astrophysics Data System (ADS)

Studerus, C.

2010-07-01

Reduze is a computer program for reducing Feynman integrals to master integrals employing a Laporta algorithm. The program is written in C++ and uses classes provided by the GiNaC library to perform the simplifications of the algebraic prefactors in the system of equations. Reduze offers the possibility to run reductions in parallel. Program summaryProgram title:Reduze Catalogue identifier: AEGE_v1_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/AEGE_v1_0.html Program obtainable from: CPC Program Library, Queen's University, Belfast, N. Ireland Licensing provisions:: yes No. of lines in distributed program, including test data, etc.: 55 433 No. of bytes in distributed program, including test data, etc.: 554 866 Distribution format: tar.gz Programming language: C++ Computer: All Operating system: Unix/Linux Number of processors used: The number of processors is problem dependent. More than one possible but not arbitrary many. RAM: Depends on the complexity of the system. Classification: 4.4, 5 External routines: CLN ( http://www.ginac.de/CLN/), GiNaC ( http://www.ginac.de/) Nature of problem: Solving large systems of linear equations with Feynman integrals as unknowns and rational polynomials as prefactors. Solution method: Using a Gauss/Laporta algorithm to solve the system of equations. Restrictions: Limitations depend on the complexity of the system (number of equations, number of kinematic invariants). Running time: Depends on the complexity of the system.

The engineering design integration (EDIN) system. [digital computer program complex

NASA Technical Reports Server (NTRS)

Glatt, C. R.; Hirsch, G. N.; Alford, G. E.; Colquitt, W. N.; Reiners, S. J.

1974-01-01

A digital computer program complex for the evaluation of aerospace vehicle preliminary designs is described. The system consists of a Univac 1100 series computer and peripherals using the Exec 8 operating system, a set of demand access terminals of the alphanumeric and graphics types, and a library of independent computer programs. Modification of the partial run streams, data base maintenance and construction, and control of program sequencing are provided by a data manipulation program called the DLG processor. The executive control of library program execution is performed by the Univac Exec 8 operating system through a user established run stream. A combination of demand and batch operations is employed in the evaluation of preliminary designs. Applications accomplished with the EDIN system are described.

Planning Complex Projects Automatically

NASA Technical Reports Server (NTRS)

Henke, Andrea L.; Stottler, Richard H.; Maher, Timothy P.

1995-01-01

Automated Manifest Planner (AMP) computer program applies combination of artificial-intelligence techniques to assist both expert and novice planners, reducing planning time by orders of magnitude. Gives planners flexibility to modify plans and constraints easily, without need for programming expertise. Developed specifically for planning space shuttle missions 5 to 10 years ahead, with modifications, applicable in general to planning other complex projects requiring scheduling of activities depending on other activities and/or timely allocation of resources. Adaptable to variety of complex scheduling problems in manufacturing, transportation, business, architecture, and construction.

Causes of catastrophic failure in complex systems

NASA Astrophysics Data System (ADS)

Thomas, David A.

2010-08-01

Root causes of mission critical failures and major cost and schedule overruns in complex systems and programs are studied through the post-mortem analyses compiled for several examples, including the Hubble Space Telescope, the Challenger and Columbia Shuttle accidents, and the Three Mile Island nuclear power plant accident. The roles of organizational complexity, cognitive biases in decision making, the display of quantitative data, and cost and schedule pressure are all considered. Recommendations for mitigating the risk of similar failures in future programs are also provided.

Computer Program for Calculation of Complex Chemical Equilibrium Compositions, Rocket Performance, Incident and Reflected Shocks, and Chapman-Jouguet Detonations. Interim Revision, March 1976

NASA Technical Reports Server (NTRS)

Gordon, S.; Mcbride, B. J.

1976-01-01

A detailed description of the equations and computer program for computations involving chemical equilibria in complex systems is given. A free-energy minimization technique is used. The program permits calculations such as (1) chemical equilibrium for assigned thermodynamic states (T,P), (H,P), (S,P), (T,V), (U,V), or (S,V), (2) theoretical rocket performance for both equilibrium and frozen compositions during expansion, (3) incident and reflected shock properties, and (4) Chapman-Jouguet detonation properties. The program considers condensed species as well as gaseous species.

Graphing Powers and Roots of Complex Numbers.

ERIC Educational Resources Information Center

Embse, Charles Vonder

1993-01-01

Using De Moivre's theorem and a parametric graphing utility, examines powers and roots of complex numbers and allows students to establish connections between the visual and numerical representations of complex numbers. Provides a program to numerically verify the roots of complex numbers. (MDH)

Using the self-select paradigm to delineate the nature of speech motor programming.

PubMed

Wright, David L; Robin, Don A; Rhee, Jooyhun; Vaculin, Amber; Jacks, Adam; Guenther, Frank H; Fox, Peter T

2009-06-01

The authors examined the involvement of 2 speech motor programming processes identified by S. T. Klapp (1995, 2003) during the articulation of utterances differing in syllable and sequence complexity. According to S. T. Klapp, 1 process, INT, resolves the demands of the programmed unit, whereas a second process, SEQ, oversees the serial order demands of longer sequences. A modified reaction time paradigm was used to assess INT and SEQ demands. Specifically, syllable complexity was dependent on syllable structure, whereas sequence complexity involved either repeated or unique syllabi within an utterance. INT execution was slowed when articulating single syllables in the form CCCV compared to simpler CV syllables. Planning unique syllables within a multisyllabic utterance rather than repetitions of the same syllable slowed INT but not SEQ. The INT speech motor programming process, important for mental syllabary access, is sensitive to changes in both syllable structure and the number of unique syllables in an utterance.

Distributed mixed-integer fuzzy hierarchical programming for municipal solid waste management. Part I: System identification and methodology development.

PubMed

Cheng, Guanhui; Huang, Guohe; Dong, Cong; Xu, Ye; Chen, Xiujuan; Chen, Jiapei

2017-03-01

Due to the existence of complexities of heterogeneities, hierarchy, discreteness, and interactions in municipal solid waste management (MSWM) systems such as Beijing, China, a series of socio-economic and eco-environmental problems may emerge or worsen and result in irredeemable damages in the following decades. Meanwhile, existing studies, especially ones focusing on MSWM in Beijing, could hardly reflect these complexities in system simulations and provide reliable decision support for management practices. Thus, a framework of distributed mixed-integer fuzzy hierarchical programming (DMIFHP) is developed in this study for MSWM under these complexities. Beijing is selected as a representative case. The Beijing MSWM system is comprehensively analyzed in many aspects such as socio-economic conditions, natural conditions, spatial heterogeneities, treatment facilities, and system complexities, building a solid foundation for system simulation and optimization. Correspondingly, the MSWM system in Beijing is discretized as 235 grids to reflect spatial heterogeneity. A DMIFHP model which is a nonlinear programming problem is constructed to parameterize the Beijing MSWM system. To enable scientific solving of it, a solution algorithm is proposed based on coupling of fuzzy programming and mixed-integer linear programming. Innovations and advantages of the DMIFHP framework are discussed. The optimal MSWM schemes and mechanism revelations will be discussed in another companion paper due to length limitation.

CYLD Deubiquitinates RIP1 in the TNFα-Induced Necrosome to Facilitate Kinase Activation and Programmed Necrosis

PubMed Central

Moquin, David M.; McQuade, Thomas; Chan, Francis Ka-Ming

2013-01-01

Background Necroptosis/programmed necrosis is initiated by a macro-molecular protein complex termed the necrosome. Receptor interacting protein kinase 1 (RIPK1/RIP1) and RIP3 are key components of the necrosome. TNFα is a prototypic inducer of necrosome activation, and it is widely believed that deubiquitination of RIP1 at the TNFR-1 signaling complex precedes transition of RIP1 into the cytosol where it forms the RIP1-RIP3 necrosome. Cylindromatosis (CYLD) is believed to promote programmed necrosis by facilitating RIP1 deubiquitination at this membrane receptor complex. Methodology/Principal Findings We demonstrate that RIP1 is indeed the primary target of CYLD in TNFα-induced programmed necrosis. We observed that CYLD does not regulate RIP1 ubiquitination at the TNF receptor. TNF and zVAD-induced programmed necrosis was highly attenuated in CYLD-/- cells. However, in the presence of cycloheximide or SMAC mimetics, programmed necrosis was only moderately reduced in CYLD-/- cells. Under the latter conditions, RIP1-RIP3 necrosome formation is only delayed, but not abolished in CYLD-/- cells. We further demonstrate that RIP1 within the NP-40 insoluble necrosome is ubiquitinated and that CYLD regulates RIP1 ubiquitination in this compartment. Hence, RIP1 ubiquitination in this late-forming complex is greatly increased in CYLD-/- cells. Increased RIP1 ubiquitination impairs RIP1 and RIP3 phosphorylation, a signature of kinase activation. Conclusions/Significance Our results show that CYLD regulates RIP1 ubiquitination in the TNFα-induced necrosome, but not in the TNFR-1 signaling complex. In cells sensitized to programmed necrosis with SMAC mimetics, CYLD is not essential for necrosome assembly. Since SMAC mimetics induces the loss of the E3 ligases cIAP1 and cIAP2, reduced RIP1 ubiquitination could lead to reduced requirement for CYLD to remove ubiquitin chains from RIP1 in the TNFR-1 complex. As increased RIP1 ubiquitination in the necrosome correlates with impaired RIP1 and RIP3 phosphorylation and function, these results suggest that CYLD controls RIP1 kinase activity during necrosome assembly. PMID:24098568

Multi-dimensional Rankings, Program Termination, and Complexity Bounds of Flowchart Programs

NASA Astrophysics Data System (ADS)

Alias, Christophe; Darte, Alain; Feautrier, Paul; Gonnord, Laure

Proving the termination of a flowchart program can be done by exhibiting a ranking function, i.e., a function from the program states to a well-founded set, which strictly decreases at each program step. A standard method to automatically generate such a function is to compute invariants for each program point and to search for a ranking in a restricted class of functions that can be handled with linear programming techniques. Previous algorithms based on affine rankings either are applicable only to simple loops (i.e., single-node flowcharts) and rely on enumeration, or are not complete in the sense that they are not guaranteed to find a ranking in the class of functions they consider, if one exists. Our first contribution is to propose an efficient algorithm to compute ranking functions: It can handle flowcharts of arbitrary structure, the class of candidate rankings it explores is larger, and our method, although greedy, is provably complete. Our second contribution is to show how to use the ranking functions we generate to get upper bounds for the computational complexity (number of transitions) of the source program. This estimate is a polynomial, which means that we can handle programs with more than linear complexity. We applied the method on a collection of test cases from the literature. We also show the links and differences with previous techniques based on the insertion of counters.

Dynamic Resectorization and Coordination Technology: An Evaluation of Air Traffic Control Complexity

NASA Technical Reports Server (NTRS)

Brinton, Christopher R.

1996-01-01

The work described in this report is done under contract with the National Aeronautics and Space Administration (NASA) to support the Advanced Air Transportation Technology (AATR) program. The goal of this program is to contribute to and accelerate progress in Advanced Air Transportation Technologies. Wyndemere Incorporated is supporting this goal by studying the complexity of the Air Traffic Specialist's role in maintaining the safety of the Air Transportation system. It is envisioned that the implementation of Free Flight may significantly increase the complexity and difficulty of maintaining this safety. Wyndemere Incorporated is researching potential methods to reduce this complexity. This is the final report for the contract.

Minimum Hamiltonian Ascent Trajectory Evaluation (MASTRE) program (update to automatic flight trajectory design, performance prediction, and vehicle sizing for support of Shuttle and Shuttle derived vehicles) engineering manual

NASA Technical Reports Server (NTRS)

Lyons, J. T.

1993-01-01

The Minimum Hamiltonian Ascent Trajectory Evaluation (MASTRE) program and its predecessors, the ROBOT and the RAGMOP programs, have had a long history of supporting MSFC in the simulation of space boosters for the purpose of performance evaluation. The ROBOT program was used in the simulation of the Saturn 1B and Saturn 5 vehicles in the 1960's and provided the first utilization of the minimum Hamiltonian (or min-H) methodology and the steepest ascent technique to solve the optimum trajectory problem. The advent of the Space Shuttle in the 1970's and its complex airplane design required a redesign of the trajectory simulation code since aerodynamic flight and controllability were required for proper simulation. The RAGMOP program was the first attempt to incorporate the complex equations of the Space Shuttle into an optimization tool by using an optimization method based on steepest ascent techniques (but without the min-H methodology). Development of the complex partial derivatives associated with the Space Shuttle configuration and using techniques from the RAGMOP program, the ROBOT program was redesigned to incorporate these additional complexities. This redesign created the MASTRE program, which was referred to as the Minimum Hamiltonian Ascent Shuttle TRajectory Evaluation program at that time. Unique to this program were first-stage (or booster) nonlinear aerodynamics, upper-stage linear aerodynamics, engine control via moment balance, liquid and solid thrust forces, variable liquid throttling to maintain constant acceleration limits, and a total upgrade of the equations used in the forward and backward integration segments of the program. This modification of the MASTRE code has been used to simulate the new space vehicles associated with the National Launch Systems (NLS). Although not as complicated as the Space Shuttle, the simulation and analysis of the NLS vehicles required additional modifications to the MASTRE program in the areas of providing additional flexibility in the use of the program, allowing additional optimization options, and providing special options for the NLS configuration.

A Wideband Fast Multipole Method for the two-dimensional complex Helmholtz equation

NASA Astrophysics Data System (ADS)

Cho, Min Hyung; Cai, Wei

2010-12-01

A Wideband Fast Multipole Method (FMM) for the 2D Helmholtz equation is presented. It can evaluate the interactions between N particles governed by the fundamental solution of 2D complex Helmholtz equation in a fast manner for a wide range of complex wave number k, which was not easy with the original FMM due to the instability of the diagonalized conversion operator. This paper includes the description of theoretical backgrounds, the FMM algorithm, software structures, and some test runs. Program summaryProgram title: 2D-WFMM Catalogue identifier: AEHI_v1_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/AEHI_v1_0.html Program obtainable from: CPC Program Library, Queen's University, Belfast, N. Ireland Licensing provisions: Standard CPC licence, http://cpc.cs.qub.ac.uk/licence/licence.html No. of lines in distributed program, including test data, etc.: 4636 No. of bytes in distributed program, including test data, etc.: 82 582 Distribution format: tar.gz Programming language: C Computer: Any Operating system: Any operating system with gcc version 4.2 or newer Has the code been vectorized or parallelized?: Multi-core processors with shared memory RAM: Depending on the number of particles N and the wave number k Classification: 4.8, 4.12 External routines: OpenMP ( http://openmp.org/wp/) Nature of problem: Evaluate interaction between N particles governed by the fundamental solution of 2D Helmholtz equation with complex k. Solution method: Multilevel Fast Multipole Algorithm in a hierarchical quad-tree structure with cutoff level which combines low frequency method and high frequency method. Running time: Depending on the number of particles N, wave number k, and number of cores in CPU. CPU time increases as N log N.

The Coordinated School Health Program: Implementation in a Rural Elementary School District

ERIC Educational Resources Information Center

Miller, Kim H.; Bice, Matthew R.

2014-01-01

Child health is a complex issue that requires a comprehensive approach to address the many factors that influence it and are influenced by it. In light of the complexity of children's health, the Coordinated School Health Program (CSHP) was developed as a framework for a systems approach to planning and implementing school-based children's health…

Wildland fire management policy: Learning from the past and present and responding to future challenges

Treesearch

Tom Zimmerman

2009-01-01

Since its origin as a defined functional activity, wildland fire management has been the natural resource management program with the highest risk, complexity, and greatest potential for serious negative outcomes. During this time, this program has continually grown in temporal and spatial extent, operational complexity, ecological significance, social, economic, and...

Marketing, Information, and Parental Choice: A Comparative Case Study of Third-Party, Federally Funded Out-of-School-Time Services

ERIC Educational Resources Information Center

Stewart, Molly S.; Good, Annalee G.

2016-01-01

Information and promotional marketing play central but complex roles in market-based educational programs. This in-depth qualitative study examines these complexities using the case of Supplemental Educational Services, a parental choice program providing federally funded tutoring to low-income students in K-12 public schools. Examining the…

simSchool: The Game of Teaching

ERIC Educational Resources Information Center

Zibit, Melanie; Gibson, David

2005-01-01

"simSchool" is a classroom simulation program funded by the Preparing Tomorrow's Teachers to Teach with Technology (PT3) program of the U.S. Department of Education. Just as a flight-simulator immerses a player in the complexities of flying a plane, "simSchool" immerses novice teachers in some of the complexities of teaching 7th-12th grade…

Enabling Requirements-Based Programming for Highly-Dependable Complex Parallel and Distributed Systems

NASA Technical Reports Server (NTRS)

Hinchey, Michael G.; Rash, James L.; Rouff, Christopher A.

2005-01-01

The manual application of formal methods in system specification has produced successes, but in the end, despite any claims and assertions by practitioners, there is no provable relationship between a manually derived system specification or formal model and the customer's original requirements. Complex parallel and distributed system present the worst case implications for today s dearth of viable approaches for achieving system dependability. No avenue other than formal methods constitutes a serious contender for resolving the problem, and so recognition of requirements-based programming has come at a critical juncture. We describe a new, NASA-developed automated requirement-based programming method that can be applied to certain classes of systems, including complex parallel and distributed systems, to achieve a high degree of dependability.

A national survey of residents in combined Internal Medicine and Dermatology residency programs: educational experience and future plans.

PubMed

Mostaghimi, Arash; Wanat, Karolyn; Crotty, Bradley H; Rosenbach, Misha

2015-10-16

In response to a perceived erosion of medical dermatology, combined internal medicine and dermatology programs (med/derm) programs have been developed that aim to train dermatologists who take care of medically complex patients. Despite the investment in these programs, there is currently no data with regards to the potential impact of these trainees on the dermatology workforce. To determine the experiences, motivations, and future plans of residents in combined med/derm residency programs. We surveyed residents at all United States institutions with both categorical and combined training programs in spring of 2012. Respondents used visual analog scales to rate clinical interests, self-assessed competency, career plans, and challenges. The primary study outcomes were comfort in taking care of patients with complex disease, future practice plans, and experience during residency. Twenty-eight of 31 med/derm residents (87.5%) and 28 of 91 (31%) categorical residents responded (overall response rate 46%). No significant differences were seen in self-assessed dermatology competency, or comfort in performing inpatient consultations, cosmetic procedures, or prescribing systemic agents. A trend toward less comfort in general dermatology was seen among med/derm residents. Med/derm residents were more likely to indicate career preferences for performing inpatient consultation and taking care of medically complex patients. Categorical residents rated their programs and experiences more highly. Med/derm residents have stronger interests in serving medically complex patients. Categorical residents are more likely to have a positive experience during residency. Future work will be needed to ascertain career choices among graduates once data are available.

Overview of Aro Program on Network Science for Human Decision Making

NASA Astrophysics Data System (ADS)

West, Bruce J.

This program brings together researchers from disparate disciplines to work on a complex research problem that defies confinement within any single discipline. Consequently, not only are new and rewarding solutions sought and obtained for a problem of importance to society and the Army, that is, the human dimension of complex networks, but, in addition, collaborations are established that would not otherwise have formed given the traditional disciplinary compartmentalization of research. This program develops the basic research foundation of a science of networks supporting the linkage between the physical and human (cognitive and social) domains as they relate to human decision making. The strategy is to extend the recent methods of non-equilibrium statistical physics to non-stationary, renewal stochastic processes that appear to be characteristic of the interactions among nodes in complex networks. We also pursue understanding of the phenomenon of synchronization, whose mathematical formulation has recently provided insight into how complex networks reach accommodation and cooperation. The theoretical analyses of complex networks, although mathematically rigorous, often elude analytic solutions and require computer simulation and computation to analyze the underlying dynamic process.

Availability and Diversity of Training Programs for Responders to International Disasters and Complex Humanitarian Emergencies

PubMed Central

Jacquet, Gabrielle A.; Obi, Chioma C.; Chang, Mary P.; Bayram, Jamil D.

2014-01-01

Introduction: Volunteers and members of relief organizations increasingly seek formal training prior to international field deployment. This paper identifies training programs for personnel responding to international disasters and complex humanitarian emergencies, and provides concise information – if available- regarding the founding organization, year established, location, cost, duration of training, participants targeted, and the content of each program. Methods: An environmental scan was conducted through a combination of a peer-reviewed literature search and an open Internet search for the training programs. Literature search engines included EMBASE, Cochrane, Scopus, PubMed, Web of Science databases using the search terms “international,” “disaster,” “complex humanitarian emergencies,” “training,” and “humanitarian response”. Both searches were conducted between January 2, 2013 and September 12, 2013. Results: 14 peer-reviewed articles mentioned or described eight training programs, while open Internet search revealed 13 additional programs. In total, twenty-one training programs were identified as currently available for responders to international disasters and CHE. Each of the programs identified has different goals and objectives, duration, expenses, targeted trainees and modules. Each of the programs identified has different goals and objectives, duration, expenses, targeted trainees and modules. Seven programs (33%) are free of charge and four programs (19%) focus on the mental aspects of disasters. The mean duration for each training program is 5 to 7 days. Fourteen of the trainings are conducted in multiple locations (66%), two in Cuba (9%) and two in Australia (9%). The cost-reported in US dollars- ranges from $100 to $2,400 with a mean cost of $480 and a median cost of $135. Most of the programs are open to the public, but some are only available by invitation only, such as the International Mobilization Preparation for Action (IMPACT) and the United Nations Humanitarian Civil-Military Coordination (UN-CMCoord) Field Course. Conclusions: A variety of training programs are available for responders to disasters and complex humanitarian emergencies. These programs vary in their objectives, audiences, modules, geographical locations, eligibility and financial cost. This paper presents an overview of available programs and serves as a resource for potential responders interested in capacity-building training prior to deployment. PMID:24987573

Learning Human Aspects of Collaborative Software Development

ERIC Educational Resources Information Center

Hadar, Irit; Sherman, Sofia; Hazzan, Orit

2008-01-01

Collaboration has become increasingly widespread in the software industry as systems have become larger and more complex, adding human complexity to the technological complexity already involved in developing software systems. To deal with this complexity, human-centric software development methods, such as Extreme Programming and other agile…

PCSYS: The optimal design integration system picture drawing system with hidden line algorithm capability for aerospace vehicle configurations

NASA Technical Reports Server (NTRS)

Hague, D. S.; Vanderburg, J. D.

1977-01-01

A vehicle geometric definition based upon quadrilateral surface elements to produce realistic pictures of an aerospace vehicle. The PCSYS programs can be used to visually check geometric data input, monitor geometric perturbations, and to visualize the complex spatial inter-relationships between the internal and external vehicle components. PCSYS has two major component programs. The between program, IMAGE, draws a complex aerospace vehicle pictorial representation based on either an approximate but rapid hidden line algorithm or without any hidden line algorithm. The second program, HIDDEN, draws a vehicle representation using an accurate but time consuming hidden line algorithm.

Petascale computation performance of lightweight multiscale cardiac models using hybrid programming models.

PubMed

Pope, Bernard J; Fitch, Blake G; Pitman, Michael C; Rice, John J; Reumann, Matthias

2011-01-01

Future multiscale and multiphysics models must use the power of high performance computing (HPC) systems to enable research into human disease, translational medical science, and treatment. Previously we showed that computationally efficient multiscale models will require the use of sophisticated hybrid programming models, mixing distributed message passing processes (e.g. the message passing interface (MPI)) with multithreading (e.g. OpenMP, POSIX pthreads). The objective of this work is to compare the performance of such hybrid programming models when applied to the simulation of a lightweight multiscale cardiac model. Our results show that the hybrid models do not perform favourably when compared to an implementation using only MPI which is in contrast to our results using complex physiological models. Thus, with regards to lightweight multiscale cardiac models, the user may not need to increase programming complexity by using a hybrid programming approach. However, considering that model complexity will increase as well as the HPC system size in both node count and number of cores per node, it is still foreseeable that we will achieve faster than real time multiscale cardiac simulations on these systems using hybrid programming models.

Zone leveling and solution growth of complex compound semiconductors in space

NASA Technical Reports Server (NTRS)

Bachmann, K. J.

1986-01-01

A research program on complex semiconducting compounds and alloys was completed that addressed the growth of single crystals of CdSe(y)Te(1-y), Zn(x)Cd(1-x)Te, Mn(x)Cd(1-x)Te, InP(y)As(1-y) and CuInSe2 and the measurement of fundamental physico-chemical properties characterizing the above materials. The purpose of this ground based research program was to lay the foundations for further research concerning the growth of complex ternary compound semiconductors in a microgravity environment.

KSC-99pp1061

NASA Image and Video Library

1999-08-23

A worker takes a measurement for construction of the Reusable Launch Vehicle (RLV) complex at KSC. Located near the Shuttle Landing Facility, the complex will include facilities for related ground support equipment and administrative/ technical support. It will be available to accommodate the Space Shuttle; the X-34 RLV technology demonstrator; the L-1011 carrier aircraft for Pegasus and X-34; and other RLV and X-vehicle programs. The complex is jointly funded by the Spaceport Florida Authority, NASA's Space Shuttle Program and KSC. The facility will be operational in early 2000

KSC-99pp1063

NASA Image and Video Library

1999-08-23

At the construction site of the Reusable Launch Vehicle (RLV) complex at KSC, workers take measurements for one of the buildings. Located near the Shuttle Landing Facility, the complex will include facilities for related ground support equipment and administrative/ technical support. It will be available to accommodate the Space Shuttle; the X-34 RLV technology demonstrator; the L-1011 carrier aircraft for Pegasus and X-34; and other RLV and X-vehicle programs. The complex is jointly funded by the Spaceport Florida Authority, NASA's Space Shuttle Program and KSC. The facility will be operational in early 2000

KSC-99pp1261

NASA Image and Video Library

1999-10-29

The support building at the $8 million Reusable Launch Vehicle (RLV) Support Complex at Kennedy Space Center takes form. It will house related ground support equipment and administrative/technical support. The RLV complex includes a multi-purpose hangar that will be available to accommodate the Space Shuttle; the X-34 RLV technology demonstrator; the L-1011 carrier aircraft for Pegasus and X-34; and other RLV and X-vehicle programs. The complex is jointly funded by the Spaceport Florida Authority, NASA's Space Shuttle Program and KSC. The facility will be operational in early 2000

KSC-99pp1062

NASA Image and Video Library

1999-08-23

At the construction site of the Reusable Launch Vehicle (RLV) complex at KSC, a worker takes a measurement. Located near the Shuttle Landing Facility, the complex will include facilities for related ground support equipment and administrative/ technical support. It will be available to accommodate the Space Shuttle; the X-34 RLV technology demonstrator; the L-1011 carrier aircraft for Pegasus and X-34; and other RLV and X-vehicle programs. The complex is jointly funded by the Spaceport Florida Authority, NASA's Space Shuttle Program and KSC. The facility will be operational in early 2000

KSC-99pp1060

NASA Image and Video Library

1999-08-23

Construction is under way for the X-33/X-34 hangar complex near the Shuttle Landing Facility at KSC. The Reusable Launch Vehicle (RLV) complex will include facilities for related ground support equipment and administrative/ technical support. It will be available to accommodate the Space Shuttle; the X-34 RLV technology demonstrator; the L-1011 carrier aircraft for Pegasus and X-34; and other RLV and X-vehicle programs. The complex is jointly funded by the Spaceport Florida Authority, NASA's Space Shuttle Program and KSC. The facility will be operational in early 2000

Programs for transferring data between a relational data base and a finite element structural analysis program

NASA Technical Reports Server (NTRS)

Johnson, S. C.

1982-01-01

An interface system for passing data between a relational information management (RIM) data base complex and engineering analysis language (EAL), a finite element structural analysis program is documented. The interface system, implemented on a CDC Cyber computer, is composed of two FORTRAN programs called RIM2EAL and EAL2RIM. The RIM2EAL reads model definition data from RIM and creates a file of EAL commands to define the model. The EAL2RIM reads model definition and EAL generated analysis data from EAL's data library and stores these data dirctly in a RIM data base. These two interface programs and the format for the RIM data complex are described.

Computer program for determining mass properties of a rigid structure

NASA Technical Reports Server (NTRS)

Hull, R. A.; Gilbert, J. L.; Klich, P. J.

1978-01-01

A computer program was developed for the rapid computation of the mass properties of complex structural systems. The program uses rigid body analyses and permits differences in structural material throughout the total system. It is based on the premise that complex systems can be adequately described by a combination of basic elemental shapes. Simple geometric data describing size and location of each element and the respective material density or weight of each element were the only required input data. From this minimum input, the program yields system weight, center of gravity, moments of inertia and products of inertia with respect to mutually perpendicular axes through the system center of gravity. The program also yields mass properties of the individual shapes relative to component axes.

Impact of the Primary Care Exception on Family Medicine Resident Coding.

PubMed

Cawse-Lucas, Jeanne; Evans, David V; Ruiz, David R; Allcut, Elizabeth A; Andrilla, C Holly A; Thompson, Matthew; Norris, Thomas E

2016-03-01

The Medicare Primary Care Exception (PCE) allows residents to see and bill for less-complex patients independently in the primary care setting, requiring attending physicians only to see patients for higher-level visits and complete physical exams in order to bill for them as such. Primary care residencies apply the PCE in various ways. We investigated the impact of the PCE on resident coding practices. Family medicine residency directors in a five-state region completed a survey regarding interpretation and application of the PCE, including the number of established patient evaluation and management codes entered by residents and attending faculty at their institution. The percentage of high-level codes was compared between residencies using chi-square tests. We analyzed coding data for 125,016 visits from 337 residents and 172 faculty physicians in 15 of 18 eligible family medicine residencies. Among programs applying the PCE criteria to all patients, residents billed 86.7% low-mid complexity and 13.3% high-complexity visits. In programs that only applied the PCE to Medicare patients, residents billed 74.9% low-mid complexity visits and 25.2% high-complexity visits. Attending physicians coded more high-complexity visits at both types of programs. The estimated revenue loss over the 1,650 RRC-required outpatient visits was $2,558.66 per resident and $57,569.85 per year for the average residency in our sample. Residents at family medicine programs that apply the PCE to all patients bill significantly fewer high-complexity visits. This finding leads to compliance and regulatory concerns and suggests significant revenue loss. Further study is required to determine whether this discrepancy also reflects inaccuracy in coding.

A computer program to trace seismic ray distribution in complex two-dimensional geological models

USGS Publications Warehouse

Yacoub, Nazieh K.; Scott, James H.

1970-01-01

A computer program has been developed to trace seismic rays and their amplitudes and energies through complex two-dimensional geological models, for which boundaries between elastic units are defined by a series of digitized X-, Y-coordinate values. Input data for the program includes problem identification, control parameters, model coordinates and elastic parameter for the elastic units. The program evaluates the partitioning of ray amplitude and energy at elastic boundaries, computes the total travel time, total travel distance and other parameters for rays arising at the earth's surface. Instructions are given for punching program control cards and data cards, and for arranging input card decks. An example of printer output for a simple problem is presented. The program is written in FORTRAN IV language. The listing of the program is shown in the Appendix, with an example output from a CDC-6600 computer.

Teaching Machines and Programmed Instruction.

ERIC Educational Resources Information Center

Kay, Harry; And Others

The various devices used in programed instruction range from the simple linear programed book to branching and skip branching programs, adaptive teaching machines, and even complex computer based systems. In order to provide a background for the would-be programer, the essential principles of each of these devices is outlined. Different ideas of…

Complex Instruction and Teaming: The Relationship between School Organization and the Introduction of an Instructional Innovation.

ERIC Educational Resources Information Center

Lee, Ginny; Filby, Nikola

This document presents findings of a study that examined the impact of teacher teaming on the implementation of a comprehensive program of curriculum and instruction. The program, Complex Instruction (CI), was implemented in four middle schools in the Riverdale School District (Arizona), each of which utilized some form of teaming instruction. CI…

Early and School-Age Care in Santa Monica: Current System, Policy Options, and Recommendations

ERIC Educational Resources Information Center

Pierson, Ashley; Karoly, Lynn A.; Zellman, Gail L.; Beckett, Megan K.

2014-01-01

The landscape of early learning and out-of-school-time programs in the City of Santa Monica is complex, with numerous providers and funding streams. This complexity reflects its evolution in response to changes in federal, state, and local priorities and initiatives. Future shifts in funding levels, program auspices, and other features are likely.…

A Complex Systems Perspective of Risk Mitigation and Modeling in Development and Acquisition Programs

DTIC Science & Technology

2016-04-30

also that we have started building in a domain where structural patterns matter, especially for large projects. Complex Systems Complexity has been...through minimalistic thinking and parsimony” and perceived elegance, which “hides systemic or organizational complexity from the user.” If the system

Construction continues on RLV Support Complex at SLF

NASA Technical Reports Server (NTRS)

1999-01-01

An aerial view reveals (foreground) the ongoing construction of an $8 million Reusable Launch Vehicle (RLV) Support Complex at Kennedy Space Center. At left is a multi-purpose hangar and at right a building for related ground support equipment and administrative/ technical support. In the background is the Vehicle Assembly Building. The road at right is the tow-way. The RLV complex will be available to accommodate the Space Shuttle; the X-34 RLV technology demonstrator; the L-1011 carrier aircraft for Pegasus and X-34; and other RLV and X-vehicle programs. The complex is jointly funded by the Spaceport Florida Authority, NASA's Space Shuttle Program and KSC. The facility will be operational in early 2000.

KSC-99pp1209

NASA Image and Video Library

1999-10-14

Construction continues on an $8 million Reusable Launch Vehicle (RLV) Support Complex at Kennedy Space Center. At left is a multi-purpose hangar and at right a building for related ground support equipment and administrative/ technical support. The complex is situated at the Shuttle Landing Facility (upper right). Near the top of the photo is the tow-way. The RLV complex will be available to accommodate the Space Shuttle; the X-34 RLV technology demonstrator; the L-1011 carrier aircraft for Pegasus and X-34; and other RLV and X-vehicle programs. The complex is jointly funded by the Spaceport Florida Authority, NASA's Space Shuttle Program and KSC. The facility will be operational in early 2000

KSC-99pp1210

NASA Image and Video Library

1999-10-14

An aerial closeup view reveals the ongoing construction of an $8 million Reusable Launch Vehicle (RLV) Support Complex at Kennedy Space Center. At right is a multi-purpose hangar and at left a building for related ground support equipment and administrative/ technical support. The complex is situated at the Shuttle Landing Facility. Near the top of the photo can be seen the tow-way. The RLV complex will be available to accommodate the Space Shuttle; the X-34 RLV technology demonstrator; the L-1011 carrier aircraft for Pegasus and X-34; and other RLV and X-vehicle programs. The complex is jointly funded by the Spaceport Florida Authority, NASA's Space Shuttle Program and KSC. The facility will be operational in early 2000

A beginner's guide to Pickett's SPCAT/SPFIT

NASA Astrophysics Data System (ADS)

Novick, Stewart E.

2016-11-01

Two of the most powerful and versatile high resolution spectroscopic predicting and fitting programs are SPCAT/SPFIT first presented by Herbert Pickett in 1991 and refined, expanded, and updated by Herb until his retirement from the Jet Propulsion Laboratory (JPL) in 2008. With versatility, unfortunately, comes complexity. The purpose of this paper is to present for the beginning spectroscopist (or the seasoned spectroscopist unfamiliar with these programs) a simple introduction to SPCAT/SPFIT. I will not be presenting the most powerful and sophisticated uses of these programs. I leave that for future articles, not necessarily by me. This paper outlines the file structures of the input and output files of the programs and a simple tutorial on how to run the programs. Simple examples are worked out, supported by a website containing the files and notes on more complex uses of the program.

- XSUMMER- Transcendental functions and symbolic summation in FORM

NASA Astrophysics Data System (ADS)

Moch, S.; Uwer, P.

2006-05-01

Harmonic sums and their generalizations are extremely useful in the evaluation of higher-order perturbative corrections in quantum field theory. Of particular interest have been the so-called nested sums, where the harmonic sums and their generalizations appear as building blocks, originating for example, from the expansion of generalized hypergeometric functions around integer values of the parameters. In this paper we discuss the implementation of several algorithms to solve these sums by algebraic means, using the computer algebra system FORM. Program summaryTitle of program:XSUMMER Catalogue identifier:ADXQ_v1_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/ADXQ_v1_0 Program obtainable from:CPC Program Library, Queen's University of Belfast, N. Ireland License:GNU Public License and FORM License Computers:all Operating system:all Program language:FORM Memory required to execute:Depending on the complexity of the problem, recommended at least 64 MB RAM No. of lines in distributed program, including test data, etc.:9854 No. of bytes in distributed program, including test data, etc.:126 551 Distribution format:tar.gz Other programs called:none External files needed:none Nature of the physical problem:Systematic expansion of higher transcendental functions in a small parameter. The expansions arise in the calculation of loop integrals in perturbative quantum field theory. Method of solution:Algebraic manipulations of nested sums. Restrictions on complexity of the problem:Usually limited only by the available disk space. Typical running time:Dependent on the complexity of the problem.

Non-Formal Educator Use of Evaluation Results

ERIC Educational Resources Information Center

Baughman, Sarah; Boyd, Heather H.; Franz, Nancy K.

2012-01-01

Increasing demands for accountability in educational programming have resulted in increasing calls for program evaluation in educational organizations. Many organizations include conducting program evaluations as part of the job responsibilities of program staff. Cooperative Extension is a complex organization offering non-formal educational…

FORTRAN 4 computer program for calculation of thermodynamic and transport properties of complex chemical systems

NASA Technical Reports Server (NTRS)

Svehla, R. A.; Mcbride, B. J.

1973-01-01

A FORTRAN IV computer program for the calculation of the thermodynamic and transport properties of complex mixtures is described. The program has the capability of performing calculations such as:(1) chemical equilibrium for assigned thermodynamic states, (2) theoretical rocket performance for both equilibrium and frozen compositions during expansion, (3) incident and reflected shock properties, and (4) Chapman-Jouguet detonation properties. Condensed species, as well as gaseous species, are considered in the thermodynamic calculation; but only the gaseous species are considered in the transport calculations.

Effect of formal specifications on program complexity and reliability: An experimental study

NASA Technical Reports Server (NTRS)

Goel, Amrit L.; Sahoo, Swarupa N.

1990-01-01

The results are presented of an experimental study undertaken to assess the improvement in program quality by using formal specifications. Specifications in the Z notation were developed for a simple but realistic antimissile system. These specifications were then used to develop 2 versions in C by 2 programmers. Another set of 3 versions in Ada were independently developed from informal specifications in English. A comparison of the reliability and complexity of the resulting programs suggests the advantages of using formal specifications in terms of number of errors detected and fault avoidance.

Computing quantum hashing in the model of quantum branching programs

NASA Astrophysics Data System (ADS)

Ablayev, Farid; Ablayev, Marat; Vasiliev, Alexander

2018-02-01

We investigate the branching program complexity of quantum hashing. We consider a quantum hash function that maps elements of a finite field into quantum states. We require that this function is preimage-resistant and collision-resistant. We consider two complexity measures for Quantum Branching Programs (QBP): a number of qubits and a number of compu-tational steps. We show that the quantum hash function can be computed efficiently. Moreover, we prove that such QBP construction is optimal. That is, we prove lower bounds that match the constructed quantum hash function computation.

Genome complexity, robustness and genetic interactions in digital organisms

NASA Astrophysics Data System (ADS)

Lenski, Richard E.; Ofria, Charles; Collier, Travis C.; Adami, Christoph

1999-08-01

Digital organisms are computer programs that self-replicate, mutate and adapt by natural selection. They offer an opportunity to test generalizations about living systems that may extend beyond the organic life that biologists usually study. Here we have generated two classes of digital organism: simple programs selected solely for rapid replication, and complex programs selected to perform mathematical operations that accelerate replication through a set of defined `metabolic' rewards. To examine the differences in their genetic architecture, we introduced millions of single and multiple mutations into each organism and measured the effects on the organism's fitness. The complex organisms are more robust than the simple ones with respect to the average effects of single mutations. Interactions among mutations are common and usually yield higher fitness than predicted from the component mutations assuming multiplicative effects; such interactions are especially important in the complex organisms. Frequent interactions among mutations have also been seen in bacteria, fungi and fruitflies. Our findings support the view that interactions are a general feature of genetic systems.

Genome complexity, robustness and genetic interactions in digital organisms.

PubMed

Lenski, R E; Ofria, C; Collier, T C; Adami, C

1999-08-12

Digital organisms are computer programs that self-replicate, mutate and adapt by natural selection. They offer an opportunity to test generalizations about living systems that may extend beyond the organic life that biologists usually study. Here we have generated two classes of digital organism: simple programs selected solely for rapid replication, and complex programs selected to perform mathematical operations that accelerate replication through a set of defined 'metabolic' rewards. To examine the differences in their genetic architecture, we introduced millions of single and multiple mutations into each organism and measured the effects on the organism's fitness. The complex organisms are more robust than the simple ones with respect to the average effects of single mutations. Interactions among mutations are common and usually yield higher fitness than predicted from the component mutations assuming multiplicative effects; such interactions are especially important in the complex organisms. Frequent interactions among mutations have also been seen in bacteria, fungi and fruitflies. Our findings support the view that interactions are a general feature of genetic systems.

Strategies to Reduce Hospitalizations of Children With Medical Complexity Through Complex Care: Expert Perspectives.

PubMed

Coller, Ryan J; Nelson, Bergen B; Klitzner, Thomas S; Saenz, Adrianna A; Shekelle, Paul G; Lerner, Carlos F; Chung, Paul J

Interventions to reduce disproportionate hospital use among children with medical complexity (CMC) are needed. We conducted a rigorous, structured process to develop intervention strategies aiming to reduce hospitalizations within a complex care program population. A complex care medical home program used 1) semistructured interviews of caregivers of CMC experiencing acute, unscheduled hospitalizations and 2) literature review on preventing hospitalizations among CMC to develop key drivers for lowering hospital utilization and link them with intervention strategies. Using an adapted version of the RAND/UCLA Appropriateness Method, an expert panel rated each model for effectiveness at impacting each key driver and ultimately reducing hospitalizations. The complex care program applied these findings to select a final set of feasible intervention strategies for implementation. Intervention strategies focused on expanding access to familiar providers, enhancing general or technical caregiver knowledge and skill, creating specific and proactive crisis or contingency plans, and improving transitions between hospital and home. Activities aimed to facilitate family-centered, flexible implementation and consideration of all of the child's environments, including school and while traveling. Tailored activities and special attention to the highest utilizing subset of CMC were also critical for these interventions. A set of intervention strategies to reduce hospitalizations among CMC, informed by key drivers, can be created through a structured, reproducible process. Both this process and the results may be relevant to clinical programs and researchers aiming to reduce hospital utilization through the medical home for CMC. Copyright © 2017 Academic Pediatric Association. Published by Elsevier Inc. All rights reserved.

76 FR 60050 - Medicaid Program: Money Follows the Person Rebalancing Demonstration Program

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-28

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Medicare & Medicaid Services Medicaid Program: Money Follows the Person Rebalancing Demonstration Program AGENCY: Centers for Medicare & Medicaid..., particularly given the complexity and vulnerability of the populations being served in MFP and the Congress...

Language Program Evaluation

ERIC Educational Resources Information Center

Norris, John M.

2016-01-01

Language program evaluation is a pragmatic mode of inquiry that illuminates the complex nature of language-related interventions of various kinds, the factors that foster or constrain them, and the consequences that ensue. Program evaluation enables a variety of evidence-based decisions and actions, from designing programs and implementing…

Using organization theory to understand the determinants of effective implementation of worksite health promotion programs.

PubMed

Weiner, Bryan J; Lewis, Megan A; Linnan, Laura A

2009-04-01

The field of worksite health promotion has moved toward the development and testing of comprehensive programs that target health behaviors with interventions operating at multiple levels of influence. Yet, observational and process evaluation studies indicate that such programs are challenging for worksites to implement effectively. Research has identified several organizational factors that promote or inhibit effective implementation of comprehensive worksite health promotion programs. However, no integrated theory of implementation has emerged from this research. This article describes a theory of the organizational determinants of effective implementation of comprehensive worksite health promotion programs. The model is adapted from theory and research on the implementation of complex innovations in manufacturing, education and health care settings. The article uses the Working Well Trial to illustrate the model's theoretical constructs. Although the article focuses on comprehensive worksite health promotion programs, the conceptual model may also apply to other types of complex health promotion programs. An organization-level theory of the determinants of effective implementation of worksite health promotion programs.

"You Get More Than You Give": Experiences of Community Partners in Facilitating Active Recreation with Individuals who have Complex Communication Needs.

PubMed

Hajjar, David J; McCarthy, John W; Benigno, Joann P; Chabot, Jennifer

2016-06-01

Recreation is an essential part of life that provides enriching experiences that may define one's life course similar to careers or other interests. An understanding of the role of volunteers in active community-based recreational programs can help to generate ways to enhance participation and contribute to additional communication opportunities with people who have complex communication needs. Nine volunteers from two adaptive ski programs and one therapeutic horseback-riding program in the Northeast region of the United States participated in semi-structured interviews. Audio-recordings were transcribed and analyzed and resulted in five thematic areas: (a) benefits, (b) why individuals volunteer, (c) barriers, (d) successful program supports, and (e) who are the riders and skiers using AAC. The findings provided insight to support the notion that active community-based recreational activities foster an environment for communication, meaningful engagement, and social relationships between volunteers and people with complex communication needs.

Using the Self-Select Paradigm to Delineate the Nature of Speech Motor Programming

PubMed Central

Wright, David L.; Robin, Don A.; Rhee, Jooyhun; Vaculin, Amber; Jacks, Adam; Guenther, Frank H.; Fox, Peter T.

2015-01-01

Purpose The authors examined the involvement of 2 speech motor programming processes identified by S. T. Klapp (1995, 2003) during the articulation of utterances differing in syllable and sequence complexity. According to S. T. Klapp, 1 process, INT, resolves the demands of the programmed unit, whereas a second process, SEQ, oversees the serial order demands of longer sequences. Method A modified reaction time paradigm was used to assess INT and SEQ demands. Specifically, syllable complexity was dependent on syllable structure, whereas sequence complexity involved either repeated or unique syllabi within an utterance. Results INT execution was slowed when articulating single syllables in the form CCCV compared to simpler CV syllables. Planning unique syllables within a multisyllabic utterance rather than repetitions of the same syllable slowed INT but not SEQ. Conclusions The INT speech motor programming process, important for mental syllabary access, is sensitive to changes in both syllable structure and the number of unique syllables in an utterance. PMID:19474396

Evaluation of Career Guidance Programs: Models, Methods, and Microcomputers. Information Series No. 317.

ERIC Educational Resources Information Center

Crites, John O.

Evaluating the effectiveness of career guidance programs is a complex process, and few comprehensive models for evaluating such programs exist. Evaluation of career guidance programs has been hampered by the myth that program outcomes are uniform and monolithic. Findings from studies of attribute treatment interactions have revealed only a few…

Science information systems: Visualization

NASA Technical Reports Server (NTRS)

Wall, Ray J.

1991-01-01

Future programs in earth science, planetary science, and astrophysics will involve complex instruments that produce data at unprecedented rates and volumes. Current methods for data display, exploration, and discovery are inadequate. Visualization technology offers a means for the user to comprehend, explore, and examine complex data sets. The goal of this program is to increase the effectiveness and efficiency of scientists in extracting scientific information from large volumes of instrument data.

KSC-2012-6390

NASA Image and Video Library

2012-12-04

CAPE CANAVERAL, Fla. – At the Kennedy Space Center Visitor Complex in Florida sixth-grade students listen to a science presentation on NASA programs. Between Nov. 26 and Dec. 7, 2012, about 5,300 sixth-graders in Brevard County, Florida were bused to Kennedy's Visitor Complex for Brevard Space Week, an educational program designed to encourage interest in science, technology, engineering and mathematics STEM careers. Photo credit: NASA/Tim Jacobs

Effects of Direct Instruction Rewards Program Strategies to Teach Separation of Complex Words to Two High School Students with Disabilities

ERIC Educational Resources Information Center

Mullaney, Lauren; Baker, Megan; Rutherford, Katie; Neyman, Jennifer; McLaughlin, T. F.; Stookey, Susan

2014-01-01

The purpose of the study was to evaluate the effects of the Direct Instruction REWARDS® program on reading complex words of two fifteen-year-old boys in a reading resource room. Both participants had difficulty in reading and were diagnosed as learning disabled. During baseline, both participants had difficulty in syllabication. The results showed…

An O({radical}nL) primal-dual affine scaling algorithm for linear programming

DOE Office of Scientific and Technical Information (OSTI.GOV)

Huang, Siming

1994-12-31

We present a new primal-dual affine scaling algorithm for linear programming. The search direction of the algorithm is a combination of classical affine scaling direction of Dikin and a recent new affine scaling direction of Jansen, Roos and Terlaky. The algorithm has an iteration complexity of O({radical}nL), comparing to O(nL) complexity of Jansen, Roos and Terlaky.

1993 Annual report on scientific programs: A broad research program on the sciences of complexity

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1993-12-31

This report provides a summary of many of the research projects completed by the Santa Fe Institute (SFI) during 1993. These research efforts continue to focus on two general areas: the study of, and search for, underlying scientific principles governing complex adaptive systems, and the exploration of new theories of computation that incorporate natural mechanisms of adaptation (mutation, genetics, evolution).

On Machine Capacitance Dimensional and Surface Profile Measurement System

NASA Technical Reports Server (NTRS)

Resnick, Ralph

1993-01-01

A program was awarded under the Air Force Machine Tool Sensor Improvements Program Research and Development Announcement to develop and demonstrate the use of a Capacitance Sensor System including Capacitive Non-Contact Analog Probe and a Capacitive Array Dimensional Measurement System to check the dimensions of complex shapes and contours on a machine tool or in an automated inspection cell. The manufacturing of complex shapes and contours and the subsequent verification of those manufactured shapes is fundamental and widespread throughout industry. The critical profile of a gear tooth; the overall shape of a graphite EDM electrode; the contour of a turbine blade in a jet engine; and countless other components in varied applications possess complex shapes that require detailed and complex inspection procedures. Current inspection methods for complex shapes and contours are expensive, time-consuming, and labor intensive.

General chemical kinetics computer program for static and flow reactions, with application to combustion and shock-tube kinetics

NASA Technical Reports Server (NTRS)

Bittker, D. A.; Scullin, V. J.

1972-01-01

A general chemical kinetics program is described for complex, homogeneous ideal-gas reactions in any chemical system. Its main features are flexibility and convenience in treating many different reaction conditions. The program solves numerically the differential equations describing complex reaction in either a static system or one-dimensional inviscid flow. Applications include ignition and combustion, shock wave reactions, and general reactions in a flowing or static system. An implicit numerical solution method is used which works efficiently for the extreme conditions of a very slow or a very fast reaction. The theory is described, and the computer program and users' manual are included.

Improved neutron activation prediction code system development

NASA Technical Reports Server (NTRS)

Saqui, R. M.

1971-01-01

Two integrated neutron activation prediction code systems have been developed by modifying and integrating existing computer programs to perform the necessary computations to determine neutron induced activation gamma ray doses and dose rates in complex geometries. Each of the two systems is comprised of three computational modules. The first program module computes the spatial and energy distribution of the neutron flux from an input source and prepares input data for the second program which performs the reaction rate, decay chain and activation gamma source calculations. A third module then accepts input prepared by the second program to compute the cumulative gamma doses and/or dose rates at specified detector locations in complex, three-dimensional geometries.

Assumption-aware tools and agency; an interrogation of the primary artifacts of the program evaluation and design profession in working with complex evaluands and complex contexts.

PubMed

Morrow, Nathan; Nkwake, Apollo M

2016-12-01

Like artisans in a professional guild, we evaluators create tools to suit our ever evolving practice. The tools we use as evaluators are the primary artifacts of our profession, reflect our practice and embody an amalgamation of paradigms and assumptions. With the increasing shifts in evaluation purposes from judging program worth to understanding how programs work, the evaluator's role is changing to that of facilitating stakeholders in a learning process. This involves clarifying purposes and choices, as well as unearthing critical assumptions. In such a role, evaluators become major tool-users and begin to innovate with small refinements or produce completely new tools to fit a specific challenge or context. We interrogate the form and function of 12 tools used by evaluators when working with complex evaluands and complex contexts. The form is described in terms of traditional qualitative techniques and particular characteristics of the elements, use and presentation of each tool. Then the function of each tool is analyzed with respect to articulating assumptions and affecting the agency of evaluators and stakeholders in complex contexts. Copyright © 2016 Elsevier Ltd. All rights reserved.

Risk Adjustment May Lessen Penalties On Hospitals Treating Complex Cardiac Patients Under Medicare's Bundled Payments.

PubMed

Markovitz, Adam A; Ellimoottil, Chandy; Sukul, Devraj; Mullangi, Samyukta; Chen, Lena M; Nallamothu, Brahmajee K; Ryan, Andrew M

2017-12-01

To reduce variation in spending, Medicare has considered implementing a cardiac bundled payment program for acute myocardial infarction and coronary artery bypass graft. Because the proposed program does not account for patient risk factors when calculating hospital penalties or rewards ("reconciliation payments"), it might unfairly penalize certain hospitals. We estimated the impact of adjusting for patients' medical complexity and social risk on reconciliation payments for Medicare beneficiaries hospitalized for the two conditions in the period 2011-13. Average spending per episode was $29,394. Accounting for medical complexity substantially narrowed the gap in reconciliation payments between hospitals with high medical severity (from a penalty of $1,809 to one of $820, or a net reduction of $989), safety-net hospitals (from a penalty of $217 to one of $87, a reduction of $130), and minority-serving hospitals (from a penalty of $70 to a reward of $56, an improvement of $126) and their counterparts. Accounting for social risk alone narrowed these gaps but had minimal incremental effects after medical complexity was accounted for. Risk adjustment may preserve incentives to care for patients with complex conditions under Medicare bundled payment programs.

[Soft- and hardware support for the setup for computer tracking of radiation teletherapy].

PubMed

Tarutin, I G; Piliavets, V I; Strakh, A G; Minenko, V F; Golubovskiĭ, A I

1983-06-01

A hard and soft ware computer assisted complex has been worked out for gamma-beam therapy. The complex included all radiotherapeutic units, including a Siemens program controlled betatron with an energy of 42 MEV computer ES-1022, a Medigraf system of the processing of graphic information, a Mars-256 system for control over the homogeneity of distribution of dose rate on the field of irradiation and a package of mathematical programs to select a plan of irradiation of various tumor sites. The prospects of the utilization of such complexes in the dosimetric support of radiation therapy are discussed.

KSC-99pp1257

NASA Image and Video Library

1999-10-29

The first roof panels are placed on the multi-purpose hangar at the site of the $8 million Reusable Launch Vehicle (RLV) Support Complex at Kennedy Space Center. The RLV complex, which includes the hangar and a building for related ground support equipment and administrative/technical support, will be available to accommodate the Space Shuttle; the X-34 RLV technology demonstrator; the L-1011 carrier aircraft for Pegasus and X-34; and other RLV and X-vehicle programs. The complex is jointly funded by the Spaceport Florida Authority, NASA's Space Shuttle Program and KSC. The facility will be operational in early 2000

KSC-99pp1259

NASA Image and Video Library

1999-10-29

Work continues on construction of the multi-purpose hangar at the site of the $8 million Reusable Launch Vehicle (RLV) Support Complex at Kennedy Space Center. In the background can be seen the new construction for the building that will house related ground support equipment and administrative/technical support. The RLV complex will be available to accommodate the Space Shuttle; the X-34 RLV technology demonstrator; the L-1011 carrier aircraft for Pegasus and X-34; and other RLV and X-vehicle programs. The complex is jointly funded by the Spaceport Florida Authority, NASA's Space Shuttle Program and KSC. The facility will be operational in early 2000

KSC-99pp1262

NASA Image and Video Library

1999-10-29

Workers place the first roof panels on the multi-purpose hangar at the site of the $8 million Reusable Launch Vehicle (RLV) Support Complex at Kennedy Space Center. The RLV complex, which includes the hangar and a building for related ground support equipment and administrative/technical support, will be available to accommodate the Space Shuttle; the X-34 RLV technology demonstrator; the L-1011 carrier aircraft for Pegasus and X-34; and other RLV and X-vehicle programs. The complex is jointly funded by the Spaceport Florida Authority, NASA's Space Shuttle Program and KSC. The facility will be operational in early 2000

Meeting the Needs of Children with Disabilities

ERIC Educational Resources Information Center

Aron, Laudan Y.; Loprest, Pamela J.

2007-01-01

Seldom do the needs of children with disabilities divide neatly along program lines. Instead, children and their families navigate a large, complex, and fragmented array of programs with inconsistent eligibility standards, application procedures, and program goals. "Meeting the Needs of Children with Disabilities" examines these programs, focusing…

SOILSOLN: A Program for Teaching Equilibria Modeling of Soil Solution Composition.

ERIC Educational Resources Information Center

Wolt, Jeffrey D.

1989-01-01

Presents a computer program for use in teaching ion speciation in soil solutions. Provides information on the structure of the program, execution, and software specifications. The program estimates concentrations of ion pairs, hydrolytic species, metal-organic complexes, and free ions in solutions. (Author/RT)

Nicholas Cleveland | NREL

Science.gov Websites

tools for complex sample analysis Affiliated Research Programs Biochemical Catalysis Working Group The synthesis Catalyst characterization Catalyst testing and reaction screening Analysis of complex organics

Software For Least-Squares And Robust Estimation

NASA Technical Reports Server (NTRS)

Jeffreys, William H.; Fitzpatrick, Michael J.; Mcarthur, Barbara E.; Mccartney, James

1990-01-01

GAUSSFIT computer program includes full-featured programming language facilitating creation of mathematical models solving least-squares and robust-estimation problems. Programming language designed to make it easy to specify complex reduction models. Written in 100 percent C language.

SAP- FORTRAN STATIC SOURCE CODE ANALYZER PROGRAM (IBM VERSION)

NASA Technical Reports Server (NTRS)

Manteufel, R.

1994-01-01

The FORTRAN Static Source Code Analyzer program, SAP, was developed to automatically gather statistics on the occurrences of statements and structures within a FORTRAN program and to provide for the reporting of those statistics. Provisions have been made for weighting each statistic and to provide an overall figure of complexity. Statistics, as well as figures of complexity, are gathered on a module by module basis. Overall summed statistics are also accumulated for the complete input source file. SAP accepts as input syntactically correct FORTRAN source code written in the FORTRAN 77 standard language. In addition, code written using features in the following languages is also accepted: VAX-11 FORTRAN, IBM S/360 FORTRAN IV Level H Extended; and Structured FORTRAN. The SAP program utilizes two external files in its analysis procedure. A keyword file allows flexibility in classifying statements and in marking a statement as either executable or non-executable. A statistical weight file allows the user to assign weights to all output statistics, thus allowing the user flexibility in defining the figure of complexity. The SAP program is written in FORTRAN IV for batch execution and has been implemented on a DEC VAX series computer under VMS and on an IBM 370 series computer under MVS. The SAP program was developed in 1978 and last updated in 1985.

SAP- FORTRAN STATIC SOURCE CODE ANALYZER PROGRAM (DEC VAX VERSION)

NASA Technical Reports Server (NTRS)

Merwarth, P. D.

1994-01-01

The FORTRAN Static Source Code Analyzer program, SAP, was developed to automatically gather statistics on the occurrences of statements and structures within a FORTRAN program and to provide for the reporting of those statistics. Provisions have been made for weighting each statistic and to provide an overall figure of complexity. Statistics, as well as figures of complexity, are gathered on a module by module basis. Overall summed statistics are also accumulated for the complete input source file. SAP accepts as input syntactically correct FORTRAN source code written in the FORTRAN 77 standard language. In addition, code written using features in the following languages is also accepted: VAX-11 FORTRAN, IBM S/360 FORTRAN IV Level H Extended; and Structured FORTRAN. The SAP program utilizes two external files in its analysis procedure. A keyword file allows flexibility in classifying statements and in marking a statement as either executable or non-executable. A statistical weight file allows the user to assign weights to all output statistics, thus allowing the user flexibility in defining the figure of complexity. The SAP program is written in FORTRAN IV for batch execution and has been implemented on a DEC VAX series computer under VMS and on an IBM 370 series computer under MVS. The SAP program was developed in 1978 and last updated in 1985.

Homeostatis and Complexity as Integrating Tools in Gerontological Education.

ERIC Educational Resources Information Center

Richardson, Daniel; McCulloch, B. Jan; Rowles, Graham D.

2001-01-01

A gerontology doctoral program used the concepts of homeostasis and complexity to present biomedical and psychosocial issues. Data from 14 students showed that homeostasis was more useful for biomedical than psychosocial issues. Complexity helped in understanding interactions between the two. (SK)

U1A Complex

ScienceCinema

None

2018-01-16

Some of the most sophisticated experiments in the stockpile stewardship program are conducted in an environmentally safe manner, nearly 1000 feet below the ground at the site. The U1a complex a sprawling underground laboratory and tunnel complex is home to a number of unique capabilities.

Implementing the CDC’s Colorectal Cancer Screening Demonstration Program: Wisdom From the Field

PubMed Central

Rohan, Elizabeth A.; Boehm, Jennifer E.; DeGroff, Amy; Glover-Kudon, Rebecca; Preissle, Judith

2017-01-01

BACKGROUND Colorectal cancer, as the second leading cause of cancer-related deaths among men and women in the United States, represents an important area for public health intervention. Although colorectal cancer screening can prevent cancer and detect disease early when treatment is most effective, few organized public health screening programs have been implemented and evaluated. From 2005 to 2009, the Centers for Disease Control and Prevention funded 5 sites to participate in the Colorectal Cancer Screening Demonstration Program (CRCSDP), which was designed to reach medically underserved populations. METHODS The authors conducted a longitudinal, multiple case study to analyze program implementation processes. Qualitative methods included interviews with 100 stakeholders, 125 observations, and review of 19 documents. Data were analyzed within and across cases. RESULTS Several themes related to CRCSDP implementation emerged from the cross-case analysis: the complexity of colorectal cancer screening, the need for teamwork and collaboration, integration of the program into existing systems, the ability of programs to use wisdom at the local level, and the influence of social norms. Although these themes were explored independently from 1 another, interaction across themes was evident. CONCLUSIONS Colorectal cancer screening is clinically complex, and its screening methods are not well accepted by the general public; both of these circumstances have implications for program implementation. Using patient navigation, engaging in transdisciplinary teamwork, assimilating new programs into existing clinical settings, and deferring to local-level wisdom together helped to address complexity and enhance program implementation. In addition, public health efforts must confront negative social norms around colorectal cancer screening. PMID:23868482

Examining "One Grant, One Loan." NASFAA Task Force Report

ERIC Educational Resources Information Center

National Association of Student Financial Aid Administrators, 2016

2016-01-01

Growing concern over the complexity of the federal financial aid system and a push toward simplification has led to increased attention toward streamlining the federal student aid programs. Specifically, several proposals and policy papers have recommended consolidating the federal aid programs into one grant program and one loan program, commonly…

75 FR 44 - Temporary Suspension of the Population Estimates and Income Estimates Challenge Programs

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-04

..., conduct research to enhance the estimates and challenge programs, and to integrate the updates from the... local governments would increase the administrative and evaluative complexity of this program for the... comparison with the population estimates, conducting research to enhance the estimates and challenge programs...

Using Small-Step Refinement for Algorithm Verification in Computer Science Education

ERIC Educational Resources Information Center

Simic, Danijela

2015-01-01

Stepwise program refinement techniques can be used to simplify program verification. Programs are better understood since their main properties are clearly stated, and verification of rather complex algorithms is reduced to proving simple statements connecting successive program specifications. Additionally, it is easy to analyse similar…

Agent planning in AgScala

NASA Astrophysics Data System (ADS)

Tošić, Saša; Mitrović, Dejan; Ivanović, Mirjana

2013-10-01

Agent-oriented programming languages are designed to simplify the development of software agents, especially those that exhibit complex, intelligent behavior. This paper presents recent improvements of AgScala, an agent-oriented programming language based on Scala. AgScala includes declarative constructs for managing beliefs, actions and goals of intelligent agents. Combined with object-oriented and functional programming paradigms offered by Scala, it aims to be an efficient framework for developing both purely reactive, and more complex, deliberate agents. Instead of the Prolog back-end used initially, the new version of AgScala relies on Agent Planning Package, a more advanced system for automated planning and reasoning.

Environmental projects. Volume 1: Polychlorinated biphenyl (PCB) abatement program

NASA Technical Reports Server (NTRS)

Kushner, L.

1987-01-01

Six large parabolic dish antennas are located at the Goldstone Deep Space Communications Complex north of Barstow, California. Some of the ancillary electrical equipment of thes Deep Space Stations, particularly transformers and power capicitors, were filled with stable, fire-retardant, dielectric fluids containing substances called polychlorobiphenyls (PCBs). Because the Environmental Protection Agency has determined that PCBs are environmental pollutants toxic to humans, all NASA centers have been asked to participate in a PCB-abatement program. Under the supervision of JPL's Office of Telecommunications and Data Acquisition, a two-year long PCB-abatement program has eliminated PCBs from the Goldstone Complex.

A program-level management system for the life cycle environmental and economic assessment of complex building projects

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kim, Chan-Joong; Kim, Jimin; Hong, Taehoon

Climate change has become one of the most significant environmental issues, of which about 40% come from the building sector. In particular, complex building projects with various functions have increased, which should be managed from a program-level perspective. Therefore, this study aimed to develop a program-level management system for the life-cycle environmental and economic assessment of complex building projects. The developed system consists of three parts: (i) input part: database server and input data; (ii) analysis part: life cycle assessment and life cycle cost; and (iii) result part: microscopic analysis and macroscopic analysis. To analyze the applicability of the developedmore » system, this study selected ‘U’ University, a complex building project consisting of research facility and residential facility. Through value engineering with experts, a total of 137 design alternatives were established. Based on these alternatives, the macroscopic analysis results were as follows: (i) at the program-level, the life-cycle environmental and economic cost in ‘U’ University were reduced by 6.22% and 2.11%, respectively; (ii) at the project-level, the life-cycle environmental and economic cost in research facility were reduced 6.01% and 1.87%, respectively; and those in residential facility, 12.01% and 3.83%, respective; and (iii) for the mechanical work at the work-type-level, the initial cost was increased 2.9%; but the operation and maintenance phase was reduced by 20.0%. As a result, the developed system can allow the facility managers to establish the operation and maintenance strategies for the environmental and economic aspects from a program-level perspective. - Highlights: • A program-level management system for complex building projects was developed. • Life-cycle environmental and economic assessment can be conducted using the system. • The design alternatives can be analyzed from the microscopic perspective. • The system can be used to establish the optimal O&M strategy at the program-level. • It can be applied to any other country or sector in the global environment.« less

Complex Plasma Physics and Rising Above the Gathering Storm

NASA Astrophysics Data System (ADS)

Hyde, Truell

2008-11-01

Research in complex plasma is prevalent across a variety of regimes ranging from the majority of plasma processing environments to many astrophysical settings. Dust particles suspended within such plasmas acquire a charge from collisions with electrons and ions in the plasma. Depending upon the ratio of their interparticle potential energy to their average kinetic energy, once charged these particles can form a gaseous, liquid or crystalline structure with short to longer range ordering. The field of complex plasmas thus offers research opportunities across a wide range of academic disciplines including physics, chemistry, biology, mathematics, electrical engineering and nanoscience. The field of complex plasmas also offers unique educational research opportunities for combating many of the issues raised in Rising Above the Gathering Storm, recently published by the National Academies Press. CASPER's Educational Outreach programs, supported by the National Science Foundation, the Department of Education and the Department of Labor takes advantage of these opportunities through a variety of avenues including a REU / RET program, a High School Scholars Program, integrated curriculum development and the CASPER Physics Circus. Together, these programs impact thousands of students and parents while providing K-12 teachers with curriculum, supporting hands-on material and support for introducing plasma and basic physical science concepts into the classroom. Both research results and educational outreach concepts from the above will be discussed.

Automated a complex computer aided design concept generated using macros programming

NASA Astrophysics Data System (ADS)

Rizal Ramly, Mohammad; Asrokin, Azharrudin; Abd Rahman, Safura; Zulkifly, Nurul Ain Md

2013-12-01

Changing a complex Computer Aided design profile such as car and aircraft surfaces has always been difficult and challenging. The capability of CAD software such as AutoCAD and CATIA show that a simple configuration of a CAD design can be easily modified without hassle, but it is not the case with complex design configuration. Design changes help users to test and explore various configurations of the design concept before the production of a model. The purpose of this study is to look into macros programming as parametric method of the commercial aircraft design. Macros programming is a method where the configurations of the design are done by recording a script of commands, editing the data value and adding a certain new command line to create an element of parametric design. The steps and the procedure to create a macro programming are discussed, besides looking into some difficulties during the process of creation and advantage of its usage. Generally, the advantages of macros programming as a method of parametric design are; allowing flexibility for design exploration, increasing the usability of the design solution, allowing proper contained by the model while restricting others and real time feedback changes.

Multiple Choice Knapsack Problem: example of planning choice in transportation.

PubMed

Zhong, Tao; Young, Rhonda

2010-05-01

Transportation programming, a process of selecting projects for funding given budget and other constraints, is becoming more complex as a result of new federal laws, local planning regulations, and increased public involvement. This article describes the use of an integer programming tool, Multiple Choice Knapsack Problem (MCKP), to provide optimal solutions to transportation programming problems in cases where alternative versions of projects are under consideration. In this paper, optimization methods for use in the transportation programming process are compared and then the process of building and solving the optimization problems is discussed. The concepts about the use of MCKP are presented and a real-world transportation programming example at various budget levels is provided. This article illustrates how the use of MCKP addresses the modern complexities and provides timely solutions in transportation programming practice. While the article uses transportation programming as a case study, MCKP can be useful in other fields where a similar decision among a subset of the alternatives is required. Copyright 2009 Elsevier Ltd. All rights reserved.

Discovering Link Communities in Complex Networks by an Integer Programming Model and a Genetic Algorithm

PubMed Central

Li, Zhenping; Zhang, Xiang-Sun; Wang, Rui-Sheng; Liu, Hongwei; Zhang, Shihua

2013-01-01

Identification of communities in complex networks is an important topic and issue in many fields such as sociology, biology, and computer science. Communities are often defined as groups of related nodes or links that correspond to functional subunits in the corresponding complex systems. While most conventional approaches have focused on discovering communities of nodes, some recent studies start partitioning links to find overlapping communities straightforwardly. In this paper, we propose a new quantity function for link community identification in complex networks. Based on this quantity function we formulate the link community partition problem into an integer programming model which allows us to partition a complex network into overlapping communities. We further propose a genetic algorithm for link community detection which can partition a network into overlapping communities without knowing the number of communities. We test our model and algorithm on both artificial networks and real-world networks. The results demonstrate that the model and algorithm are efficient in detecting overlapping community structure in complex networks. PMID:24386268

Y-12 Groundwater Protection Program CY2012 Triennial Report Of The Monitoring Well Inspection And Maintenance Program Y-12 National Security Complex, Oak Ridge, Tennessee

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

2013-09-01

This document is the triennial report for the Well Inspection and Maintenance Program of the Y- 12 Groundwater Protection Program (GWPP), at the U.S. Department of Energy (DOE) Y-12 National Security Complex (Y-12). This report formally documents well inspections completed by the GWPP on active and inactive wells at Y-12 during calendar years (CY) 2010 through 2012. In addition, this report also documents well inspections performed under the Y-12 Water Resources Restoration Program, which is administered by URS|CH2M Oak Ridge (UCOR). This report documents well maintenance activities completed since the last triennial inspection event (CY 2009); and provides summary tablesmore » of well inspections and well maintenance activities during the reference time period.« less

Multiple object tracking using the shortest path faster association algorithm.

PubMed

Xi, Zhenghao; Liu, Heping; Liu, Huaping; Yang, Bin

2014-01-01

To solve the persistently multiple object tracking in cluttered environments, this paper presents a novel tracking association approach based on the shortest path faster algorithm. First, the multiple object tracking is formulated as an integer programming problem of the flow network. Then we relax the integer programming to a standard linear programming problem. Therefore, the global optimum can be quickly obtained using the shortest path faster algorithm. The proposed method avoids the difficulties of integer programming, and it has a lower worst-case complexity than competing methods but better robustness and tracking accuracy in complex environments. Simulation results show that the proposed algorithm takes less time than other state-of-the-art methods and can operate in real time.

Multiple Object Tracking Using the Shortest Path Faster Association Algorithm

PubMed Central

Liu, Heping; Liu, Huaping; Yang, Bin

2014-01-01

To solve the persistently multiple object tracking in cluttered environments, this paper presents a novel tracking association approach based on the shortest path faster algorithm. First, the multiple object tracking is formulated as an integer programming problem of the flow network. Then we relax the integer programming to a standard linear programming problem. Therefore, the global optimum can be quickly obtained using the shortest path faster algorithm. The proposed method avoids the difficulties of integer programming, and it has a lower worst-case complexity than competing methods but better robustness and tracking accuracy in complex environments. Simulation results show that the proposed algorithm takes less time than other state-of-the-art methods and can operate in real time. PMID:25215322

Computer program determines chemical equilibria in complex systems

NASA Technical Reports Server (NTRS)

Gordon, S.; Zeleznik, F. J.

1966-01-01

Computer program numerically solves nonlinear algebraic equations for chemical equilibrium based on iteration equations independent of choice of components. This program calculates theoretical performance for frozen and equilibrium composition during expansion and Chapman-Jouguet flame properties, studies combustion, and designs hardware.

Feasibility of a Team Approach to Complex Congenital Heart Defect Neurodevelopmental Follow-Up: Early Experience of a Combined Cardiology/Neonatal Intensive Care Unit Follow-Up Program.

PubMed

Chorna, Olena; Baldwin, H Scott; Neumaier, Jamie; Gogliotti, Shirley; Powers, Deborah; Mouvery, Amanda; Bichell, David; Maitre, Nathalie L

2016-07-01

Infants with complex congenital heart disease are at high risk for poor neurodevelopmental outcomes. However, implementation of dedicated congenital heart disease follow-up programs presents important infrastructure, personnel, and resource challenges. We present the development, implementation, and retrospective review of 1- and 2-year outcomes of a Complex Congenital Heart Defect Neurodevelopmental Follow-Up program. This program was a synergistic approach between the Pediatric Cardiology, Cardiothoracic Surgery, Pediatric Intensive Care, and Neonatal Intensive Care Unit Follow-Up teams to provide a feasible and responsible utilization of existing infrastructure and personnel, to develop and implement a program dedicated to children with congenital heart disease. Trained developmental testers administered the Ages and Stages Questionnaire-3 over the phone to the parents of all referred children at least once between 6 and 12 months' corrected age. At 18 months' corrected age, all children were scheduled in the Neonatal Intensive-Care Unit Follow-Up Clinic for a visit with standardized neurological exams, Bayley III, multidisciplinary therapy evaluations and continued follow-up. Of the 132 patients identified in the Cardiothoracic Surgery database and at discharge from the hospital, a total number of 106 infants were reviewed. A genetic syndrome was identified in 23.4% of the population. Neuroimaging abnormalities were identified in 21.7% of the cohort with 12.8% having visibly severe insults. As a result, 23 (26.7%) received first-time referrals for early intervention services, 16 (13.8%) received referrals for new services in addition to their existing ones. We concluded that utilization of existing resources in collaboration with established programs can ensure targeted neurodevelopmental follow-up for all children with complex congenital heart disease. © 2016 American Heart Association, Inc.

A complexity-scalable software-based MPEG-2 video encoder.

PubMed

Chen, Guo-bin; Lu, Xin-ning; Wang, Xing-guo; Liu, Ji-lin

2004-05-01

With the development of general-purpose processors (GPP) and video signal processing algorithms, it is possible to implement a software-based real-time video encoder on GPP, and its low cost and easy upgrade attract developers' interests to transfer video encoding from specialized hardware to more flexible software. In this paper, the encoding structure is set up first to support complexity scalability; then a lot of high performance algorithms are used on the key time-consuming modules in coding process; finally, at programming level, processor characteristics are considered to improve data access efficiency and processing parallelism. Other programming methods such as lookup table are adopted to reduce the computational complexity. Simulation results showed that these ideas could not only improve the global performance of video coding, but also provide great flexibility in complexity regulation.

Blended Learning Experience in a Programming Language Course and the Effect of the Thinking Styles of the Students on Success and Motivation

ERIC Educational Resources Information Center

Yagci, Mustafa

2016-01-01

High-level thinking and problem solving skill is one requirement of computer programming that most of the students experience problems with. Individual differences such as motivation, attitude towards programming, thinking style of the student, and complexity of the programming language have influence on students' success on programming. Thus,…

A new order-theoretic characterisation of the polytime computable functions☆

PubMed Central

Avanzini, Martin; Eguchi, Naohi; Moser, Georg

2015-01-01

We propose a new order-theoretic characterisation of the class of polytime computable functions. To this avail we define the small polynomial path order (sPOP⁎ for short). This termination order entails a new syntactic method to analyse the innermost runtime complexity of term rewrite systems fully automatically: for any rewrite system compatible with sPOP⁎ that employs recursion up to depth d, the (innermost) runtime complexity is polynomially bounded of degree d. This bound is tight. Thus we obtain a direct correspondence between a syntactic (and easily verifiable) condition of a program and the asymptotic worst-case complexity of the program. PMID:26412933

Automating Embedded Analysis Capabilities and Managing Software Complexity in Multiphysics Simulation, Part I: Template-Based Generic Programming

DOE PAGES

Pawlowski, Roger P.; Phipps, Eric T.; Salinger, Andrew G.

2012-01-01

An approach for incorporating embedded simulation and analysis capabilities in complex simulation codes through template-based generic programming is presented. This approach relies on templating and operator overloading within the C++ language to transform a given calculation into one that can compute a variety of additional quantities that are necessary for many state-of-the-art simulation and analysis algorithms. An approach for incorporating these ideas into complex simulation codes through general graph-based assembly is also presented. These ideas have been implemented within a set of packages in the Trilinos framework and are demonstrated on a simple problem from chemical engineering.

Networks consolidation program: Maintenance and Operations (M&O) staffing estimates

NASA Technical Reports Server (NTRS)

Goodwin, J. P.

1981-01-01

The Mark IV-A consolidate deep space and high elliptical Earth orbiter (HEEO) missions tracking and implements centralized control and monitoring at the deep space communications complexes (DSCC). One of the objectives of the network design is to reduce maintenance and operations (M&O) costs. To determine if the system design meets this objective an M&O staffing model for Goldstone was developed which was used to estimate the staffing levels required to support the Mark IV-A configuration. The study was performed for the Goldstone complex and the program office translated these estimates for the overseas complexes to derive the network estimates.

KSC-99pp1263

NASA Image and Video Library

1999-10-29

A steam roller packs down the ground next to construction of a support building, part of the $8 million Reusable Launch Vehicle (RLV) Support Complex at Kennedy Space Center. The RLV complex, which includes a multi-purpose hangar and the building to be used for related ground support equipment and administrative/technical support, will be available to accommodate the Space Shuttle; the X-34 RLV technology demonstrator; the L-1011 carrier aircraft for Pegasus and X-34; and other RLV and X-vehicle programs. The complex is jointly funded by the Spaceport Florida Authority, NASA's Space Shuttle Program and KSC. The facility will be operational in early 2000

KSC-99pp1265

NASA Image and Video Library

1999-10-29

Construction workers are silhouetted against the sky as they work on the girders of a support building, part of the new $8 million Reusable Launch Vehicle (RLV) Support Complex at Kennedy Space Center. The building is to be used for related ground support equipment and administrative/technical support. The RLV complex also includes a multi-purpose hangar. The complex will be available to accommodate the Space Shuttle; the X-34 RLV technology demonstrator; the L-1011 carrier aircraft for Pegasus and X-34; and other RLV and X-vehicle programs. The facility, jointly funded by the Spaceport Florida Authority, NASA's Space Shuttle Program and KSC, will be operational in early 2000

The Multiple Roles that Youth Development Program Leaders Adopt with Youth

ERIC Educational Resources Information Center

Walker, Kathrin C.

2011-01-01

The roles that program leaders establish in their relationships with youth structure how leaders are able to foster youth development. This article examines the complex roles program leaders create in youth programs and investigates how they balanced multiple roles to most effectively respond to the youth they serve. Analyses of qualitative data…

Systematic Literature Review Protocol: Teaching Novices Programming Using Robots

ERIC Educational Resources Information Center

Major, Louis

2010-01-01

Teaching computer programming to novices is a difficult task due to the complex nature of the subject, as negative stereotypes are associated with programming and because introductory programming courses often fail to encourage student understanding. This Protocol outlines the plan that is to be followed in order to investigate the effectiveness…

Financing Early Childhood Education Programs: State, Federal, and Local Issues

ERIC Educational Resources Information Center

Hustedt, Jason T.; Barnett, W. Steven

2011-01-01

The landscape of financing early childhood education in the U.S. is complex. Programs run the gamut from tuition-supported private centers to public programs supported by federal, state, or local funds. Different funding streams are poorly coordinated. The federal government funds several major targeted programs that are available only to specific…

A Critical Assessment of the Performance of Protein-ligand Scoring Functions Based on NMR Chemical Shift Perturbations

PubMed Central

Wang, Bing; Westerhoff, Lance M.; Merz, Kenneth M.

2008-01-01

We have generated docking poses for the FKBP-GPI complex using eight docking programs, and compared their scoring functions with scoring based on NMR chemical shift perturbations (NMRScore). Because the chemical shift perturbation (CSP) is exquisitely sensitive on the orientation of ligand inside the binding pocket, NMRScore offers an accurate and straightforward approach to score different poses. All scoring functions were inspected by their abilities to highly rank the native-like structures and separate them from decoy poses generated for a protein-ligand complex. The overall performance of NMRScore is much better than that of energy-based scoring functions associated with docking programs in both aspects. In summary, we find that the combination of docking programs with NMRScore results in an approach that can robustly determine the binding site structure for a protein-ligand complex, thereby, providing a new tool facilitating the structure-based drug discovery process. PMID:17867664

INNOVATIVE SOIL AND GROUNDWATER REMEDIATION: THE SITE PROGRAM EXPERIENCE

EPA Science Inventory

The SITE program of the USEPA has been bringing together the private sector, EPA, and other federal and state agencies to succedssfully address complex hazardous waste problems. For more than 15 years, the SITE Program has successfully promoted the development, commercialization ...

Computer program determines gas flow rates in piping systems

NASA Technical Reports Server (NTRS)

Franke, R.

1966-01-01

Computer program calculates the steady state flow characteristics of an ideal compressible gas in a complex piping system. The program calculates the stagnation and total temperature, static and total pressure, loss factor, and forces on each element in the piping system.

The Algebra of Complex Numbers.

ERIC Educational Resources Information Center

LePage, Wilbur R.

This programed text is an introduction to the algebra of complex numbers for engineering students, particularly because of its relevance to important problems of applications in electrical engineering. It is designed for a person who is well experienced with the algebra of real numbers and calculus, but who has no experience with complex number…

Communication Analysis of Information Complexes.

ERIC Educational Resources Information Center

Malik, M. F.

Communication analysis is a tool for perceptual assessment of existing or projected information complexes, i.e., an established reality perceived by one or many humans. An information complex could be of a physical nature, such as a building, landscape, city street; or of a pure informational nature, such as a film, television program,…

Evaluating the impact of a disease management program for chronic complex conditions at two large northeast health plans using a control group methodology.

PubMed

Schwerner, Henry; Mellody, Timothy; Goldstein, Allan B; Wansink, Daryl; Sullivan, Virginia; Yelenik, Stephan N; Charlton, Warwick; Lloyd, Kelley; Courtemanche, Ted

2006-02-01

The objective of this study was to observe trends in payer expenditures for plan members with one of 14 chronic, complex conditions comparing one group with a disease management program specific to their condition (the intervention group) and the other with no specific disease management program (the control group) for these conditions. The authors used payer claims and membership data to identify members eligible for the program in a 12-month baseline year (October 2001 to September 2002) and a subsequent 12-month program year (October 2002 to September 2003). Two payers were analyzed: one health plan with members primarily in New Jersey (AmeriHealth New Jersey [AHNJ]), where the disease management program was offered, and one affiliated large plan with members primarily in the metro Philadelphia area, where the program was not offered. The claims payment policy for both plans is identical. Intervention and control groups were analyzed for equivalence. The analysis was conducted in both groups over identical time periods. The intervention group showed statistically significant (p < 0.01) differences in total paid claims trend and expenditures when compared to the control group. Intervention group members showed a reduction in expenditures of -8%, while control group members showed an increase of +10% over identical time periods. Subsequent analyses controlling for outliers and product lines served to confirm the overall results. The disease management program is likely responsible for the observed difference between the intervention and control group results. A well-designed, targeted disease management program offered by a motivated, supportive health plan can play an important role in cost improvement strategies for members with complex, chronic conditions.

lsjk—a C++ library for arbitrary-precision numeric evaluation of the generalized log-sine functions

NASA Astrophysics Data System (ADS)

Kalmykov, M. Yu.; Sheplyakov, A.

2005-10-01

Generalized log-sine functions Lsj(k)(θ) appear in higher order ɛ-expansion of different Feynman diagrams. We present an algorithm for the numerical evaluation of these functions for real arguments. This algorithm is implemented as a C++ library with arbitrary-precision arithmetics for integer 0⩽k⩽9 and j⩾2. Some new relations and representations of the generalized log-sine functions are given. Program summaryTitle of program:lsjk Catalogue number:ADVS Program summary URL:http://cpc.cs.qub.ac.uk/summaries/ADVS Program obtained from: CPC Program Library, Queen's University of Belfast, N. Ireland Licensing terms: GNU General Public License Computers:all Operating systems:POSIX Programming language:C++ Memory required to execute:Depending on the complexity of the problem, at least 32 MB RAM recommended No. of lines in distributed program, including testing data, etc.:41 975 No. of bytes in distributed program, including testing data, etc.:309 156 Distribution format:tar.gz Other programs called:The CLN library for arbitrary-precision arithmetics is required at version 1.1.5 or greater External files needed:none Nature of the physical problem:Numerical evaluation of the generalized log-sine functions for real argument in the region 0<θ<π. These functions appear in Feynman integrals Method of solution:Series representation for the real argument in the region 0<θ<π Restriction on the complexity of the problem:Limited up to Lsj(9)(θ), and j is an arbitrary integer number. Thus, all function up to the weight 12 in the region 0<θ<π can be evaluated. The algorithm can be extended up to higher values of k(k>9) without modification Typical running time:Depending on the complexity of problem. See text below.

The Undiagnosed Diseases Program Integrated Collaboration System (UDPICS): One Program’s Experience Developing Custom Software to Support Research for Complex-Disease Families

PubMed Central

Guzman, Jessica; Lee, Elizabeth; Draper, David; Valivullah, Zaheer; Yu, Guoyun; Sincan, Murat; Gahl, William A.; Adams, David R.

2015-01-01

The Undiagnosed Diseases Program (UDP) was started in 2008 with the goals of making diagnoses and facilitating related translational research. The individuals and families seen by the UDP are often unique and medically complex. Approximately 40% of UDP cases are pediatric. The Undiagnosed Diseases Program Integrated Collaboration System (UDPICS) was designed to create a collaborative workspace for researchers, clinicians and families. We describe our progress in developing the system to date, focusing on design rationale, challenges and issues that are likely to be common in the development of similar systems in the future. PMID:27417368

Reasoning on Weighted Delegatable Authorizations

NASA Astrophysics Data System (ADS)

Ruan, Chun; Varadharajan, Vijay

This paper studies logic based methods for representing and evaluating complex access control policies needed by modern database applications. In our framework, authorization and delegation rules are specified in a Weighted Delegatable Authorization Program (WDAP) which is an extended logic program. We show how extended logic programs can be used to specify complex security policies which support weighted administrative privilege delegation, weighted positive and negative authorizations, and weighted authorization propagations. We also propose a conflict resolution method that enables flexible delegation control by considering priorities of authorization grantors and weights of authorizations. A number of rules are provided to achieve delegation depth control, conflict resolution, and authorization and delegation propagations.

MSC products for the simulation of tire behavior

NASA Technical Reports Server (NTRS)

Muskivitch, John C.

1995-01-01

The modeling of tires and the simulation of tire behavior are complex problems. The MacNeal-Schwendler Corporation (MSC) has a number of finite element analysis products that can be used to address the complexities of tire modeling and simulation. While there are many similarities between the products, each product has a number of capabilities that uniquely enable it to be used for a specific aspect of tire behavior. This paper discusses the following programs: (1) MSC/NASTRAN - general purpose finite element program for linear and nonlinear static and dynamic analysis; (2) MSC/ADAQUS - nonlinear statics and dynamics finite element program; (3) MSC/PATRAN AFEA (Advanced Finite Element Analysis) - general purpose finite element program with a subset of linear and nonlinear static and dynamic analysis capabilities with an integrated version of MSC/PATRAN for pre- and post-processing; and (4) MSC/DYTRAN - nonlinear explicit transient dynamics finite element program.

The National Shipbuilding Research Program, Proceedings of the REAPS Technical Symposium Paper No. 6: SPADES System Current Developments

DTIC Science & Technology

1976-06-01

and End-Cuts Program ( PLEC ). A special program to aid in fabrication of complex three-dimensional pipe structures, which is of special interest to...LENGTH AND END-CUTS PROGRAM ( PL E C) PROGRAM DESCRIPTION 1. PROGRAM CAPABILITIES The Pipe Length and End- Cuts ( PLEC ) Development Program allows the...required categories: a. Definition Input This type of input by the ’ PLEC ’ Program can be divided in two is used to define a three-dimensional structure

33 CFR 273.13 - Program policy.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Program is designed to deal primarily with weed infestations of major economic significance including... should constitute investigation of a specific problem weed or weed complex, not generalized surveys of... Control Program, except as such areas may be used for experimental purposes in research performed for the...

33 CFR 273.13 - Program policy.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Program is designed to deal primarily with weed infestations of major economic significance including... should constitute investigation of a specific problem weed or weed complex, not generalized surveys of... Control Program, except as such areas may be used for experimental purposes in research performed for the...

33 CFR 273.13 - Program policy.

Code of Federal Regulations, 2014 CFR

2014-07-01

... Program is designed to deal primarily with weed infestations of major economic significance including... should constitute investigation of a specific problem weed or weed complex, not generalized surveys of... Control Program, except as such areas may be used for experimental purposes in research performed for the...

33 CFR 273.13 - Program policy.

Code of Federal Regulations, 2012 CFR

2012-07-01

... Program is designed to deal primarily with weed infestations of major economic significance including... should constitute investigation of a specific problem weed or weed complex, not generalized surveys of... Control Program, except as such areas may be used for experimental purposes in research performed for the...

33 CFR 273.13 - Program policy.

Code of Federal Regulations, 2013 CFR

2013-07-01

... Program is designed to deal primarily with weed infestations of major economic significance including... should constitute investigation of a specific problem weed or weed complex, not generalized surveys of... Control Program, except as such areas may be used for experimental purposes in research performed for the...

The Appropriateness of Scratch and App Inventor as Educational Environments for Teaching Introductory Programming in Primary and Secondary Education

ERIC Educational Resources Information Center

Papadakis, Stamatios; Kalogiannakis, Michail; Orfanakis, Vasileios; Zaranis, Nicholas

2017-01-01

Teaching programming is a complex task. The task is even more challenging for introductory modules. There is an ongoing debate in the teaching community over the best approach to teaching introductory programming. Visual block-based programming environments allow school students to create their own programs in ways that are more accessible than in…

Advanced Simulation and Computing Business Plan

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rummel, E.

To maintain a credible nuclear weapons program, the National Nuclear Security Administration’s (NNSA’s) Office of Defense Programs (DP) needs to make certain that the capabilities, tools, and expert staff are in place and are able to deliver validated assessments. This requires a complete and robust simulation environment backed by an experimental program to test ASC Program models. This ASC Business Plan document encapsulates a complex set of elements, each of which is essential to the success of the simulation component of the Nuclear Security Enterprise. The ASC Business Plan addresses the hiring, mentoring, and retaining of programmatic technical staff responsiblemore » for building the simulation tools of the nuclear security complex. The ASC Business Plan describes how the ASC Program engages with industry partners—partners upon whom the ASC Program relies on for today’s and tomorrow’s high performance architectures. Each piece in this chain is essential to assure policymakers, who must make decisions based on the results of simulations, that they are receiving all the actionable information they need.« less

Using a commercial CAD system for simultaneous input to theoretical aerodynamic programs and wind-tunnel model construction

NASA Technical Reports Server (NTRS)

Enomoto, F.; Keller, P.

1984-01-01

The Computer Aided Design (CAD) system's common geometry database was used to generate input for theoretical programs and numerically controlled (NC) tool paths for wind tunnel part fabrication. This eliminates the duplication of work in generating separate geometry databases for each type of analysis. Another advantage is that it reduces the uncertainty due to geometric differences when comparing theoretical aerodynamic data with wind tunnel data. The system was adapted to aerodynamic research by developing programs written in Design Analysis Language (DAL). These programs reduced the amount of time required to construct complex geometries and to generate input for theoretical programs. Certain shortcomings of the Design, Drafting, and Manufacturing (DDM) software limited the effectiveness of these programs and some of the Calma NC software. The complexity of aircraft configurations suggests that more types of surface and curve geometry should be added to the system. Some of these shortcomings may be eliminated as improved versions of DDM are made available.

Russian Space Agency research and development program for Aerospace Plane combined propulsion systems ('OREL-2-1' R&D)

NASA Astrophysics Data System (ADS)

Lanshin, A.; Sosounov, V.

The 'OREL-2-1' R&D program - 'Development of Combined Propulsion Systems for Advanced Reusable Space Transportation Systems (RSTS) Using Atmospheric Air as an Oxidizer' is being conducted in 1993-1995 according to the order of the Russian Space Agency (RSA). This work is part of the complex 'OREL' R&D program - 'Complex Investigations for RSTS Development preferable Directions Basis and Making of the Scientific and Technical Experience for the RSTS Creation' at which the TsNIIMash, TsAGI and NIITP side by side the Central Institute of Aviation Motors (CIAM) are the lead organizations of the four work parts. The 'OREL-2-1' R&D program and some of its results of 1993 are described briefly in this paper.

ATM test and integration. [Skylab Apollo Telescope Mount

NASA Technical Reports Server (NTRS)

Moore, J. W.; Mitchell, J. R.

1974-01-01

The test and checkout philosophy of the test program for the Skylab ATM module and the overall test flow including in-process, post-manufacturing, vibration, thermal vacuum, and prelaunch checkout activities are described. Capabilities and limitations of the test complex and its use of automation are discussed. Experiences with the organizational principle of using a dedicated test team for all checkout activities are reported. Material on the development of the ATM subsystems, the experimental program and the requirements of the scientific community, and the integration and verification of the complex systems/subsystems of the ATM are presented. The performance of the ATM test program in such areas as alignment, systems and subsystems, contamination control, and experiment operation is evaluated. The conclusions and recommendations resulting from the ATM test program are enumerated.

The Design, Development and Testing of a Multi-process Real-time Software System

DTIC Science & Technology

2007-03-01

programming large systems stems from the complexity of dealing with many different details at one time. A sound engineering approach is to break...controls and 3) is portable to other OS platforms such as Microsoft Windows. Next, to reduce the complexity of the programming tasks, the system...processes depending on how often the process has to check to see if common data was modified. A good method for one process to quickly notify another

KSC-2012-3053

NASA Image and Video Library

2012-05-23

CAPE CANAVERAL, Fla. – A NASA Railroad train crosses the railroad’s Jay Jay Railroad Bridge north of Launch Complex 39 at NASA’s Kennedy Space Center in Florida. The train is on its way to the Florida East Coast Railway interchange in Titusville, Fla., where the train’s helium tank cars, a liquid oxygen tank car, and a liquid hydrogen dewar or tank car will be transferred for delivery to the SpaceX engine test complex outside McGregor, Texas. The railroad cars were needed in support of the Space Shuttle Program but currently are not in use by NASA following the completion of the program in 2011. Originally, the tankers belonged to the U.S. Bureau of Mines. At the peak of the shuttle program, there were approximately 30 cars in the fleet. About half the cars were returned to the bureau as launch activity diminished. Five tank cars are being loaned to SpaceX and repurposed to support their engine tests in Texas. Eight cars previously were shipped to California on loan to support the SpaceX Falcon 9 rocket launches from Space Launch Complex-4 on Vandenberg Air Force Base. SpaceX already has three helium tank cars previously used for the shuttle program at Space Launch Complex-40 on Cape Canaveral Air Force Station in Florida. For more information, visit http://www.nasa.gov/spacex. Photo credit: NASA/Jim Grossmann

KSC-2012-3052

NASA Image and Video Library

2012-05-23

CAPE CANAVERAL, Fla. – A NASA Railroad train crosses the railroad’s Jay Jay Railroad Bridge north of Launch Complex 39 at NASA’s Kennedy Space Center in Florida. The train is on its way to the Florida East Coast Railway interchange in Titusville, Fla., where the train’s helium tank cars, a liquid oxygen tank car, and a liquid hydrogen dewar or tank car will be transferred for delivery to the SpaceX engine test complex outside McGregor, Texas. The railroad cars were needed in support of the Space Shuttle Program but currently are not in use by NASA following the completion of the program in 2011. Originally, the tankers belonged to the U.S. Bureau of Mines. At the peak of the shuttle program, there were approximately 30 cars in the fleet. About half the cars were returned to the bureau as launch activity diminished. Five tank cars are being loaned to SpaceX and repurposed to support their engine tests in Texas. Eight cars previously were shipped to California on loan to support the SpaceX Falcon 9 rocket launches from Space Launch Complex-4 on Vandenberg Air Force Base. SpaceX already has three helium tank cars previously used for the shuttle program at Space Launch Complex-40 on Cape Canaveral Air Force Station in Florida. For more information, visit http://www.nasa.gov/spacex. Photo credit: NASA/Jim Grossmann

KSC-2012-2889

NASA Image and Video Library

2012-05-21

CAPE CANAVERAL, Fla. – At the NASA Railroad yard at Kennedy Space Center in Florida, cranes are enlisted to lift helium tank cars from their trucks onto flat cars in preparation for a journey to the Florida East Coast Railway interchange in Titusville, Fla., where the train’s tank cars will be transferred for delivery to the SpaceX engine test complex outside McGregor, Texas. The yard is located in Kennedy’s Launch Complex 39 near the 525-foot-tall Vehicle Assembly Building, in the background. The railroad cars were needed in support of the Space Shuttle Program but currently are not in use by NASA following the completion of the program in 2011. Originally, the tankers belonged to the U.S. Bureau of Mines. At the peak of the shuttle program, there were approximately 30 cars in the fleet. About half the cars were returned to the bureau as launch activity diminished. Five tank cars are being loaned to SpaceX and repurposed to support their engine tests in Texas. Eight cars previously were shipped to California on loan to support the SpaceX Falcon 9 rocket launches from Space Launch Complex-4 on Vandenberg Air Force Base. SpaceX already has three helium tank cars previously used for the shuttle program at Space Launch Complex-40 on Cape Canaveral Air Force Station in Florida. For more information, visit http://www.nasa.gov/spacex. Photo credit: NASA/Jim Grossmann

KSC-2012-3056

NASA Image and Video Library

2012-05-23

CAPE CANAVERAL, Fla. – A NASA Railroad train has crossed the Indian River on the railroad’s Jay Jay Railroad Bridge north of Launch Complex 39 at NASA’s Kennedy Space Center in Florida. The train is on its way to the Florida East Coast Railway interchange in Titusville, Fla., where the train’s helium tank cars, a liquid oxygen tank car, and a liquid hydrogen dewar or tank car will be transferred for delivery to the SpaceX engine test complex outside McGregor, Texas. The railroad cars were needed in support of the Space Shuttle Program but currently are not in use by NASA following the completion of the program in 2011. Originally, the tankers belonged to the U.S. Bureau of Mines. At the peak of the shuttle program, there were approximately 30 cars in the fleet. About half the cars were returned to the bureau as launch activity diminished. Five tank cars are being loaned to SpaceX and repurposed to support their engine tests in Texas. Eight cars previously were shipped to California on loan to support the SpaceX Falcon 9 rocket launches from Space Launch Complex-4 on Vandenberg Air Force Base. SpaceX already has three helium tank cars previously used for the shuttle program at Space Launch Complex-40 on Cape Canaveral Air Force Station in Florida. For more information, visit http://www.nasa.gov/spacex. Photo credit: NASA/Jim Grossmann

KSC-2012-3050

NASA Image and Video Library

2012-05-23

CAPE CANAVERAL, Fla. – A NASA Railroad train crosses the railroad’s Jay Jay Railroad Bridge north of Launch Complex 39 at NASA’s Kennedy Space Center in Florida. The train is on its way to the Florida East Coast Railway interchange in Titusville, Fla., where the train’s helium tank cars, a liquid oxygen tank car, and a liquid hydrogen dewar or tank car will be transferred for delivery to the SpaceX engine test complex outside McGregor, Texas. The railroad cars were needed in support of the Space Shuttle Program but currently are not in use by NASA following the completion of the program in 2011. Originally, the tankers belonged to the U.S. Bureau of Mines. At the peak of the shuttle program, there were approximately 30 cars in the fleet. About half the cars were returned to the bureau as launch activity diminished. Five tank cars are being loaned to SpaceX and repurposed to support their engine tests in Texas. Eight cars previously were shipped to California on loan to support the SpaceX Falcon 9 rocket launches from Space Launch Complex-4 on Vandenberg Air Force Base. SpaceX already has three helium tank cars previously used for the shuttle program at Space Launch Complex-40 on Cape Canaveral Air Force Station in Florida. For more information, visit http://www.nasa.gov/spacex. Photo credit: NASA/Jim Grossmann

KSC-2012-3051

NASA Image and Video Library

2012-05-23

CAPE CANAVERAL, Fla. – A NASA Railroad train crosses the railroad’s Jay Jay Railroad Bridge north of Launch Complex 39 at NASA’s Kennedy Space Center in Florida. The train is on its way to the Florida East Coast Railway interchange in Titusville, Fla., where the train’s helium tank cars, a liquid oxygen tank car, and a liquid hydrogen dewar or tank car will be transferred for delivery to the SpaceX engine test complex outside McGregor, Texas. The railroad cars were needed in support of the Space Shuttle Program but currently are not in use by NASA following the completion of the program in 2011. Originally, the tankers belonged to the U.S. Bureau of Mines. At the peak of the shuttle program, there were approximately 30 cars in the fleet. About half the cars were returned to the bureau as launch activity diminished. Five tank cars are being loaned to SpaceX and repurposed to support their engine tests in Texas. Eight cars previously were shipped to California on loan to support the SpaceX Falcon 9 rocket launches from Space Launch Complex-4 on Vandenberg Air Force Base. SpaceX already has three helium tank cars previously used for the shuttle program at Space Launch Complex-40 on Cape Canaveral Air Force Station in Florida. For more information, visit http://www.nasa.gov/spacex. Photo credit: NASA/Jim Grossmann

Programming of the complex logarithm function in the solution of the cracked anisotropic plate loaded by a point force

NASA Astrophysics Data System (ADS)

Zaal, K. J. J. M.

1991-06-01

In programming solutions of complex function theory, the complex logarithm function is replaced by the complex logarithmic function, introducing a discontinuity along the branch cut into the programmed solution which was not present in the mathematical solution. Recently, Liaw and Kamel presented their solution of the infinite anisotropic centrally cracked plate loaded by an arbitrary point force, which they used as Green's function in a boundary element method intended to evaluate the stress intensity factor at the tip of a crack originating from an elliptical home. Their solution may be used as Green's function of many more numerical methods involving anisotropic elasticity. In programming applications of Liaw and Kamel's solution, the standard definition of the logarithmic function with the branch cut at the nonpositive real axis cannot provide a reliable computation of the displacement field for Liaw and Kamel's solution. Either the branch cut should be redefined outside the domain of the logarithmic function, after proving that the domain is limited to a part of the plane, or the logarithmic function should be defined on its Riemann surface. A two dimensional line fractal can provide the link between all mesh points on the plane essential to evaluate the logarithm function on its Riemann surface. As an example, a two dimensional line fractal is defined for a mesh once used by Erdogan and Arin.

Assessing Fidelity of Core Components in a Mindfulness and Yoga Intervention for Urban Youth: Applying the CORE Process

ERIC Educational Resources Information Center

Gould, Laura Feagans; Mendelson, Tamar; Dariotis, Jacinda K.; Ancona, Matthew; Smith, Ali S. R.; Gonzalez, Andres A.; Smith, Atman A.; Greenberg, Mark T.

2014-01-01

In the past years, the number of mindfulness-based intervention and prevention programs has increased steadily. In order to achieve the intended program outcomes, program implementers need to understand the essential and indispensable components that define a program's success. This chapter describes the complex process of identifying the core…

A Comparison of Linear and Systems Thinking Approaches for Program Evaluation Illustrated Using the Indiana Interdisciplinary GK-12

ERIC Educational Resources Information Center

Dyehouse, Melissa; Bennett, Deborah; Harbor, Jon; Childress, Amy; Dark, Melissa

2009-01-01

Logic models are based on linear relationships between program resources, activities, and outcomes, and have been used widely to support both program development and evaluation. While useful in describing some programs, the linear nature of the logic model makes it difficult to capture the complex relationships within larger, multifaceted…

Web-Mediated Problem-Based Learning and Computer Programming: Effects of Study Approach on Academic Achievement and Attitude

ERIC Educational Resources Information Center

Yagci, Mustafa

2018-01-01

In the relevant literature, it is often debated whether learning programming requires high-level thinking skills, the lack of which consequently results in the failure of students in programming. The complex nature of programming and individual differences, including study approaches, thinking styles, and the focus of supervision, all have an…

Variable Complexity Structural Optimization of Shells

NASA Technical Reports Server (NTRS)

Haftka, Raphael T.; Venkataraman, Satchi

1999-01-01

Structural designers today face both opportunities and challenges in a vast array of available analysis and optimization programs. Some programs such as NASTRAN, are very general, permitting the designer to model any structure, to any degree of accuracy, but often at a higher computational cost. Additionally, such general procedures often do not allow easy implementation of all constraints of interest to the designer. Other programs, based on algebraic expressions used by designers one generation ago, have limited applicability for general structures with modem materials. However, when applicable, they provide easy understanding of design decisions trade-off. Finally, designers can also use specialized programs suitable for designing efficiently a subset of structural problems. For example, PASCO and PANDA2 are panel design codes, which calculate response and estimate failure much more efficiently than general-purpose codes, but are narrowly applicable in terms of geometry and loading. Therefore, the problem of optimizing structures based on simultaneous use of several models and computer programs is a subject of considerable interest. The problem of using several levels of models in optimization has been dubbed variable complexity modeling. Work under NASA grant NAG1-2110 has been concerned with the development of variable complexity modeling strategies with special emphasis on response surface techniques. In addition, several modeling issues for the design of shells of revolution were studied.

Variable Complexity Structural Optimization of Shells

NASA Technical Reports Server (NTRS)

Haftka, Raphael T.; Venkataraman, Satchi

1998-01-01

Structural designers today face both opportunities and challenges in a vast array of available analysis and optimization programs. Some programs such as NASTRAN, are very general, permitting the designer to model any structure, to any degree of accuracy, but often at a higher computational cost. Additionally, such general procedures often do not allow easy implementation of all constraints of interest to the designer. Other programs, based on algebraic expressions used by designers one generation ago, have limited applicability for general structures with modem materials. However, when applicable, they provide easy understanding of design decisions trade-off. Finally, designers can also use specialized programs suitable for designing efficiently a subset of structural problems. For example, PASCO and PANDA2 are panel design codes, which calculate response and estimate failure much more efficiently than general-purpose codes, but are narrowly applicable in terms of geometry and loading. Therefore, the problem of optimizing structures based on simultaneous use of several models and computer programs is a subject of considerable interest. The problem of using several levels of models in optimization has been dubbed variable complexity modeling. Work under NASA grant NAG1-1808 has been concerned with the development of variable complexity modeling strategies with special emphasis on response surface techniques. In addition several modeling issues for the design of shells of revolution were studied.

The 1992 annual report on scientific programs: A broad research program on the sciences of complexity

NASA Astrophysics Data System (ADS)

In 1992 the Santa Fe Institute hosted more than 100 short- and long-term research visitors who conducted a total of 212 person-months of residential research in complex systems. To date this 1992 work has resulted in more than 50 SFI Working Papers and nearly 150 publications in the scientific literature. The Institute's book series in the sciences of complexity continues to grow, now numbering more than 20 volumes. The fifth annual complex systems summer school brought nearly 60 graduate students and postdoctoral fellows to Santa Fe for an intensive introduction to the field. Research on complex systems - the focus of work at SFI - involves an extraordinary range of topics normally studied in seemingly disparate fields. Natural systems displaying complex adaptive behavior range upwards from DNA through cells and evolutionary systems to human societies. Research models exhibiting complex behavior include spin glasses, cellular automata, and genetic algorithms. Some of the major questions facing complex systems researchers are: (1) explaining how complexity arises from the nonlinear interaction of simple components; (2) describing the mechanisms underlying high-level aggregate behavior of complex systems (such as the overt behavior of an organism, the flow of energy in an ecology, and the Gross National Product (GNP) of an economy); and (3) creating a theoretical framework to enable predictions about the likely behavior of such systems in various conditions.

1992 annual report on scientific programs: A broad research program on the sciences of complexity

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1992-12-31

In 1992 the Santa Fe Institute hosted more than 100 short- and long-term research visitors who conducted a total of 212 person-months of residential research in complex systems. To date this 1992 work has resulted in more than 50 SFI Working Papers and nearly 150 publications in the scientific literature. The Institute`s book series in the sciences of complexity continues to grow, now numbering more than 20 volumes. The fifth annual complex systems summer school brought nearly 60 graduate students and postdoctoral fellows to Santa Fe for an intensive introduction to the field. Research on complex systems-the focus of workmore » at SFI-involves an extraordinary range of topics normally studied in seemingly disparate fields. Natural systems displaying complex adaptive behavior range upwards from DNA through cells and evolutionary systems to human societies. Research models exhibiting complex behavior include spin glasses, cellular automata, and genetic algorithms. Some of the major questions facing complex systems researchers are: (1) explaining how complexity arises from the nonlinear interaction of simple components; (2) describing the mechanisms underlying high-level aggregate behavior of complex systems (such as the overt behavior of an organism, the flow of energy in an ecology, the GNP of an economy); and (3) creating a theoretical framework to enable predictions about the likely behavior of such systems in various conditions.« less

Resolution of singularities for multi-loop integrals

NASA Astrophysics Data System (ADS)

Bogner, Christian; Weinzierl, Stefan

2008-04-01

We report on a program for the numerical evaluation of divergent multi-loop integrals. The program is based on iterated sector decomposition. We improve the original algorithm of Binoth and Heinrich such that the program is guaranteed to terminate. The program can be used to compute numerically the Laurent expansion of divergent multi-loop integrals regulated by dimensional regularisation. The symbolic and the numerical steps of the algorithm are combined into one program. Program summaryProgram title: sector_decomposition Catalogue identifier: AEAG_v1_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/AEAG_v1_0.html Program obtainable from: CPC Program Library, Queen's University, Belfast, N. Ireland Licensing provisions: Standard CPC licence, http://cpc.cs.qub.ac.uk/licence/licence.html No. of lines in distributed program, including test data, etc.: 47 506 No. of bytes in distributed program, including test data, etc.: 328 485 Distribution format: tar.gz Programming language: C++ Computer: all Operating system: Unix RAM: Depending on the complexity of the problem Classification: 4.4 External routines: GiNaC, available from http://www.ginac.de, GNU scientific library, available from http://www.gnu.org/software/gsl Nature of problem: Computation of divergent multi-loop integrals. Solution method: Sector decomposition. Restrictions: Only limited by the available memory and CPU time. Running time: Depending on the complexity of the problem.

Food commodity pipeline management in transitional settings: challenges and lessons learned from the first USAID food development program in South Sudan

PubMed Central

Tappis, Hannah; Doocy, Shannon; Amoako, Stephen

2013-01-01

ABSTRACT Despite decades of support for international food assistance programs by the U.S. Agency for International Development (USAID) Office of Food for Peace, relatively little is known about the commodity pipeline and management issues these programs face in post-conflict and politically volatile settings. Based on an audit of the program's commodity tracking system and interviews with 13 key program staff, this case study documents the experiences of organizations implementing the first USAID-funded non-emergency (development) food assistance program approved for Sudan and South Sudan. Key challenges and lessons learned in this experience about food commodity procurement, transport, and management may help improve the design and implementation of future development food assistance programs in a variety of complex, food-insecure settings around the world. Specifically, expanding shipping routes in complex political situations may facilitate reliable and timely commodity delivery. In addition, greater flexibility to procure commodities locally, rather than shipping U.S.-procured commodities, may avoid unnecessary shipping delays and reduce costs. PMID:25276532

Advocacy Simplified

ERIC Educational Resources Information Center

Dowd, Karen J.; Curva, Fely

2008-01-01

Most state professional associations promote and fund at some level, an advocacy program. These advocacy programs usually aim to support or plead for a program, policy, or proposal. They can range from simple communication to complex strategies, from daily interactions to annual productions, and from position papers to onsite, legislative visits.…

48 CFR 234.004 - Acquisition strategy.

Code of Federal Regulations, 2010 CFR

2010-10-01

... acquisition strategy. The documentation— (A) Shall include an explanation of the level of program risk; and (B... the reasons for proceeding with Milestone B approval despite the high level of program risk; and (iii...'s written determination that— (A) The program is so complex and technically challenging that it...

Complex sample survey estimation in static state-space

Treesearch

Raymond L. Czaplewski

2010-01-01

Increased use of remotely sensed data is a key strategy adopted by the Forest Inventory and Analysis Program. However, multiple sensor technologies require complex sampling units and sampling designs. The Recursive Restriction Estimator (RRE) accommodates this complexity. It is a design-consistent Empirical Best Linear Unbiased Prediction for the state-vector, which...

Comparing Virtual and Physical Robotics Environments for Supporting Complex Systems and Computational Thinking

ERIC Educational Resources Information Center

Berland, Matthew; Wilensky, Uri

2015-01-01

Both complex systems methods (such as agent-based modeling) and computational methods (such as programming) provide powerful ways for students to understand new phenomena. To understand how to effectively teach complex systems and computational content to younger students, we conducted a study in four urban middle school classrooms comparing…

Orchestrating liver development.

PubMed

Gordillo, Miriam; Evans, Todd; Gouon-Evans, Valerie

2015-06-15

The liver is a central regulator of metabolism, and liver failure thus constitutes a major health burden. Understanding how this complex organ develops during embryogenesis will yield insights into how liver regeneration can be promoted and how functional liver replacement tissue can be engineered. Recent studies of animal models have identified key signaling pathways and complex tissue interactions that progressively generate liver progenitor cells, differentiated lineages and functional tissues. In addition, progress in understanding how these cells interact, and how transcriptional and signaling programs precisely coordinate liver development, has begun to elucidate the molecular mechanisms underlying this complexity. Here, we review the lineage relationships, signaling pathways and transcriptional programs that orchestrate hepatogenesis. © 2015. Published by The Company of Biologists Ltd.

KSC-99PP-1212

NASA Image and Video Library

1999-10-14

An aerial view reveals (foreground) the ongoing construction of an $8 million Reusable Launch Vehicle (RLV) Support Complex at Kennedy Space Center. At left is a multi-purpose hangar and at right a building for related ground support equipment and administrative/ technical support. In the background is the Vehicle Assembly Building. The road at right is the tow-way. The RLV complex will be available to accommodate the Space Shuttle; the X-34 RLV technology demonstrator; the L-1011 carrier aircraft for Pegasus and X-34; and other RLV and X-vehicle programs. The complex is jointly funded by the Spaceport Florida Authority, NASA's Space Shuttle Program and KSC. The facility will be operational in early 2000.

KSC-98dc1879

NASA Image and Video Library

1998-12-18

An artist's rendering shows the $8-million Reusable Launch Vehicle (RLV) Support Complex planned for the Shuttle Landing Facility (SLF) at Kennedy Space Center. The ground breaking took place today. To be located at the tow-way adjacent to the SLF, the complex will include a multi-purpose RLV hangar and adjacent facilities for related ground support equipment and administrative/technical support. It will be available to accommodate the Space Shuttle, the X-34 RLV technology demonstrator, the L-1011 carrier aircraft for Pegasus and X-34, and other RLV and X-vehicle programs. The complex is jointly funded by the Spaceport Florida Authority, NASA's Space Shuttle Program and KSC. The facility will be operational in early 2000

Thermal transformation of bioactive caffeic acid on fumed silica seen by UV-Vis spectroscopy, thermogravimetric analysis, temperature programmed desorption mass spectrometry and quantum chemical methods.

PubMed

Kulik, Tetiana V; Lipkovska, Natalia O; Barvinchenko, Valentyna M; Palyanytsya, Borys B; Kazakova, Olga A; Dudik, Olesia O; Menyhárd, Alfréd; László, Krisztina

2016-05-15

Thermochemical studies of hydroxycinnamic acid derivatives and their surface complexes are important for the pharmaceutical industry, medicine and for the development of technologies of heterogeneous biomass pyrolysis. In this study, structural and thermal transformations of caffeic acid complexes on silica surfaces were studied by UV-Vis spectroscopy, thermogravimetric analysis, temperature programmed desorption mass spectrometry (TPD MS) and quantum chemical methods. Two types of caffeic acid surface complexes are found to form through phenolic or carboxyl groups. The kinetic parameters of the chemical reactions of caffeic acid on silica surface are calculated. The mechanisms of thermal transformations of the caffeic chemisorbed surface complexes are proposed. Thermal decomposition of caffeic acid complex chemisorbed through grafted ester group proceeds via three parallel reactions, producing ketene, vinyl and acetylene derivatives of 1,2-dihydroxybenzene. Immobilization of phenolic acids on the silica surface improves greatly their thermal stability. Copyright © 2016 Elsevier Inc. All rights reserved.

Interfacing theories of program with theories of evaluation for advancing evaluation practice: Reductionism, systems thinking, and pragmatic synthesis.

PubMed

Chen, Huey T

2016-12-01

Theories of program and theories of evaluation form the foundation of program evaluation theories. Theories of program reflect assumptions on how to conceptualize an intervention program for evaluation purposes, while theories of evaluation reflect assumptions on how to design useful evaluation. These two types of theories are related, but often discussed separately. This paper attempts to use three theoretical perspectives (reductionism, systems thinking, and pragmatic synthesis) to interface them and discuss the implications for evaluation practice. Reductionism proposes that an intervention program can be broken into crucial components for rigorous analyses; systems thinking view an intervention program as dynamic and complex, requiring a holistic examination. In spite of their contributions, reductionism and systems thinking represent the extreme ends of a theoretical spectrum; many real-world programs, however, may fall in the middle. Pragmatic synthesis is being developed to serve these moderate- complexity programs. These three theoretical perspectives have their own strengths and challenges. Knowledge on these three perspectives and their evaluation implications can provide a better guide for designing fruitful evaluations, improving the quality of evaluation practice, informing potential areas for developing cutting-edge evaluation approaches, and contributing to advancing program evaluation toward a mature applied science. Copyright © 2016 Elsevier Ltd. All rights reserved.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Deeb, Rula A.; Hawley, Elisabeth L.

The goal of United States (U.S.) Department of Energy's (DOE)'s environmental remediation programs is to restore groundwater to beneficial use, similar to many other Federal and state environmental cleanup programs. Based on past experience, groundwater remediation to pre-contamination conditions (i.e., drinking water standards or non-detectable concentrations) can be successfully achieved at many sites. At a subset of the most complex sites, however, complete restoration is not likely achievable within the next 50 to 100 years using today's technology. This presentation describes several approaches used at complex sites in the face of these technical challenges. Many complex sites adopted a long-termmore » management approach, whereby contamination was contained within a specified area using active or passive remediation techniques. Consistent with the requirements of their respective environmental cleanup programs, several complex sites selected land use restrictions and used risk management approaches to accordingly adopt alternative cleanup goals (alternative endpoints). Several sites used long-term management designations and approaches in conjunction with the alternative endpoints. Examples include various state designations for groundwater management zones, technical impracticability (TI) waivers or greater risk waivers at Superfund sites, and the use of Monitored Natural Attenuation (MNA) or other passive long-term management approaches over long time frames. This presentation will focus on findings, statistics, and case studies from a recently-completed report for the Department of Defense's Environmental Security Technology Certification Program (ESTCP) (Project ER-0832) on alternative endpoints and approaches for groundwater remediation at complex sites under a variety of Federal and state cleanup programs. The primary objective of the project was to provide environmental managers and regulators with tools, metrics, and information needed to evaluate alternative endpoints for groundwater remediation at complex sites. A statistical analysis of Comprehensive Environmental Response, Compensation and Liability Act (CERCLA) sites receiving TI waivers will be presented as well as case studies of other types of alternative endpoints and alternative remedial strategies that illustrate the variety of approaches used at complex sites and the technical analyses used to predict and document cost, time frame, and potential remedial effectiveness. This presentation is intended to inform DOE program managers, state regulators, practitioners and other stakeholders who are evaluating technical cleanup challenges within their own programs, and establishing programmatic approaches to evaluating and implementing long-term management approaches. Case studies provide examples of long-term management designations and strategies to manage and remediate groundwater at complex sites. At least 13 states consider some designation for groundwater containment in their corrective action policies, such as groundwater management zones, containment zones, and groundwater classification exemption areas. Long-term management designations are not a way to 'do nothing' or walk away from a site. Instead, soil and groundwater within the zone is managed to be protective of human health and the environment. Understanding when and how to adopt a long-term management approach can lead to cost savings and the more efficient use of resources across DOE and at numerous other industrial and military sites across the U.S. This presentation provides context for assessing the use and appropriate role of alternative endpoints and supporting long-term management designations in final remedies. (authors)« less

Automated validation of a computer operating system

NASA Technical Reports Server (NTRS)

Dervage, M. M.; Milberg, B. A.

1970-01-01

Programs apply selected input/output loads to complex computer operating system and measure performance of that system under such loads. Technique lends itself to checkout of computer software designed to monitor automated complex industrial systems.

Costing Complex Products, Operations, and Support

DTIC Science & Technology

2011-04-30

Symposium, 10-12 May 2011, Seaside, CA. U.S. Government or Federal Rights License 14. ABSTRACT Complex products and systems (CoPS), such as large defense...Program Executive Officer SHIPS • Commander, Naval Sea Systems Command • Army Contracting Command, U.S. Army Materiel Command • Program Manager...Airborne, Maritime and Fixed Station Joint Tactical Radio System = ==================^Åèìáëáíáçå=oÉëÉ~êÅÜW=`ob^qfkd=pvkbodv=clo=fkclojba=`e^kdb=====- ii

CDFISH: an individual-based, spatially-explicit, landscape genetics simulator for aquatic species in complex riverscapes

USGS Publications Warehouse

Erin L. Landguth,; Muhlfeld, Clint C.; Luikart, Gordon

2012-01-01

We introduce Cost Distance FISHeries (CDFISH), a simulator of population genetics and connectivity in complex riverscapes for a wide range of environmental scenarios of aquatic organisms. The spatially-explicit program implements individual-based genetic modeling with Mendelian inheritance and k-allele mutation on a riverscape with resistance to movement. The program simulates individuals in subpopulations through time employing user-defined functions of individual migration, reproduction, mortality, and dispersal through straying on a continuous resistance surface.

Transportation risk management : international practices for program development and project delivery.

DOT National Transportation Integrated Search

2012-08-01

Managing transportation networks, including agency : management, program development, and project : delivery, is extremely complex and fraught with : uncertainty. Administrators, planners, and engineers : coordinate a multitude of organizational and ...

Algorthms and prigrams complex for chaotic dynamics investigation of the Earth artificial sat-ellites. (Russian Title: Комплекс алгоритмов и программ для исследования хаотичности в динамике искусственных спутников Земли )

NASA Astrophysics Data System (ADS)

Bordovitsyna, T. V.; Aleksandrova, A. G.; Chuvashov, I. N.

2010-12-01

In this paper complex of algorithms and programs for revelation and investigation of dynamical chaotic state in the motion of the Earth artificial satellites by parallel computing is presented. Complex has been based on the program "Numerical model of the system artificial satellites motion" for cluster "Skiff Cyberia". Factor MEGNO as main indicator of chaotic state has been used. The factor is computed by combined numerical integration of equations of the motion, equations in variation and equations of MEGNO parameters. The results of program complex testing in the problem of MEGNO parameters calculation for different types of geostationary orbits are presented.

Case Management for Patients with Complex Multimorbidity: Development and Validation of a Coordinated Intervention between Primary and Hospital Care

PubMed Central

Giménez-Campos, María Soledad; Villar-López, Julia; Faubel-Cava, Raquel; Donat-Castelló, Lucas; Valdivieso-Martínez, Bernardo; Soriano-Melchor, Elisa; Bahamontes-Mulió, Amparo; García-Gómez, Juan M.

2017-01-01

In the past few years, healthcare systems have been facing a growing demand related to the high prevalence of chronic diseases. Case management programs have emerged as an integrated care approach for the management of chronic disease. Nevertheless, there is little scientific evidence on the impact of using a case management program for patients with complex multimorbidity regarding hospital resource utilisation. We evaluated an integrated case management intervention set up by community-based care at outpatient clinics with nurse case managers from a telemedicine unit. The hypothesis to be tested was whether improved continuity of care resulting from the integration of community-based and hospital services reduced the use of hospital resources amongst patients with complex multimorbidity. A retrospective cohort study was performed using a sample of 714 adult patients admitted to the program between January 2012 and January 2015. We found a significant decrease in the number of emergency room visits, unplanned hospitalizations, and length of stay, and an expected increase in the home care hospital-based episodes. These results support the hypothesis that case management interventions can reduce the use of unplanned hospital admissions when applied to patients with complex multimorbidity. PMID:28970745

Health Services, Student Services Department: Program Evaluation. 1990-91.

ERIC Educational Resources Information Center

Jeschke, Thomas; And Others

This document evaluates the Des Moines Public Schools health services and education program, which utilizes the professional expertise of school nurses throughout the district. The program promotes success in the learning process for students (including those with complex health care needs, conditions, and disabilities), employees, and the…

76 FR 22437 - Bureau of Educational and Cultural Affairs (ECA) Request for Grant Proposals; Community Solutions...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-21

... complex global challenges related to the participants' community activities. Strong project designs will... program include participation in the design and direction of program implementation including recruitment... Partner Countries: Proposals need to embrace a global program design that incorporates all of the proposed...

48 CFR 19.804-1 - Agency evaluation.

Code of Federal Regulations, 2010 CFR

2010-10-01

... items or work similar in nature and complexity to that specified in the business plan; (c) Problems... SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Contracting With the Small Business Administration (the 8(a... support of the 8(a) Program, the agency should evaluate— (a) Its current and future plans to acquire the...

Television Program Complexity and Ratings.

ERIC Educational Resources Information Center

Krull, Robert; Watt, James H., Jr.

This paper applied findings from studies using the kind of viewing measures used by social scientists, to the relationship between programing and viewership when viewership is measured by means used by producers. Total aggregate viewership and the relationship of viewers' ages to viewership was concentrated on. Effects of competing programs on…

Using Curriculum-Based Measurements for Program Evaluation: Expanding Roles for School Psychologists

ERIC Educational Resources Information Center

Tusing, Mary E.; Breikjern, Nicholle A.

2017-01-01

Educators increasingly need to evaluate schoolwide reform efforts; however, complex program evaluations often are not feasible in schools. Through a case example, we provide a heuristic for program evaluation that is easily replicated in schools. Criterion-referenced interpretations of schoolwide screening data were used to evaluate outcomes…

Are Water-Related Leadership Development Programs Designed to Be Effective? An Exploratory Study

ERIC Educational Resources Information Center

Burbach, Mark E.; Floress, Kristin; Kaufman, Eric K.

2015-01-01

Water resource professionals and others involved in managing water resources face increasingly complex challenges. Effective leadership development programs are needed to produce water leaders who can address these challenges. Leadership programs must be designed not simply to increase participants' environmental and leadership knowledge but to…

A Regional Serials Program under National Serials Data Program Auspices: Discussion Paper Prepared for Ad Hoc Serials Discussion Group

ERIC Educational Resources Information Center

Grosch, Audrey N.

1973-01-01

A regionally organized program for serials bibliography is proposed because of the large volume of complex data needing control and the many purposes to which the data can be put in support of regional or local needs. (2 references) (Author)

Leadership Training Program for Medical Staff in Belgium

ERIC Educational Resources Information Center

Claes, Neree; Brabanders, Valérie

2016-01-01

Today healthcare is facing many challenges in a volatile, uncertain, complex and ambiguous environment. There is a need to develop strong leaders who can cope with these challenges. This article describes the process of a leadership training program for healthcare professionals in Belgium (named "Clinical Leadership Program" or…

Competency Tests and Graduation Requirements. Second Edition.

ERIC Educational Resources Information Center

Keefe, James W.

Interest in applied performance testing and concern about the quality of the high school diploma are finding a common ground: graduation requirements. A competency is a complex capability applicable in real life situations, and can be used as program objectives in a competency-based, criterion-referenced program. In such a program, applied…

Assessing Quality in Home Visiting Programs

ERIC Educational Resources Information Center

Korfmacher, Jon; Laszewski, Audrey; Sparr, Mariel; Hammel, Jennifer

2013-01-01

Defining quality and designing a quality assessment measure for home visitation programs is a complex and multifaceted undertaking. This article summarizes the process used to create the Home Visitation Program Quality Rating Tool (HVPQRT) and identifies next steps for its development. The HVPQRT measures both structural and dynamic features of…

The Future Problem Solving Program.

ERIC Educational Resources Information Center

Crabbe, Anne B.

1989-01-01

Describes the Future Problem Solving Program, in which students from the U.S. and around the world are tackling some complex challenges facing society, ranging from acid rain to terrorism. The program uses a creative problem solving process developed for business and industry. A sixth-grade toxic waste cleanup project illustrates the process.…

Synchronization in Scratch: A Case Study with Education Science Students

ERIC Educational Resources Information Center

Nikolos, Dimitris; Komis, Vassilis

2015-01-01

The Scratch programming language is an introductory programming language for students. It is also a visual concurrent programming language, where multiple threads are executed simultaneously. Synchronization in concurrent languages is a complex task for novices to understand. Our research is focused on strategies and methods applied by novice…

The Program Evaluation Guide: A Preliminary Review of Special Education Instruction

ERIC Educational Resources Information Center

Nulty, Elizabeth C.

2017-01-01

Special education programs vary in the quality of services provided across states, cities, and school districts. There are three major components necessary for a quality special education program for children with complex learning needs. These components include systems level analysis, capacity building for staff, and strong individual student…

Linear Programming for Vocational Education Planning. Interim Report.

ERIC Educational Resources Information Center

Young, Robert C.; And Others

The purpose of the paper is to define for potential users of vocational education management information systems a quantitative analysis technique and its utilization to facilitate more effective planning of vocational education programs. Defining linear programming (LP) as a management technique used to solve complex resource allocation problems…

MSFC Skylab lessons learned

NASA Technical Reports Server (NTRS)

1974-01-01

Key lessons learned during the Skylab Program that could have impact on on-going and future programs are presented. They present early and sometimes subjective opinions; however, they give insights into key areas of concern. These experiences from a complex space program management and space flight serve as an early assessment to provide the most advantage to programs underway. References to other more detailed reports are provided.

Scheduling language and algorithm development study. Volume 1: Study summary and overview

NASA Technical Reports Server (NTRS)

1974-01-01

A high level computer programming language and a program library were developed to be used in writing programs for scheduling complex systems such as the space transportation system. The objectives and requirements of the study are summarized and unique features of the specified language and program library are described and related to the why of the objectives and requirements.

Applications of genetic programming in cancer research.

PubMed

Worzel, William P; Yu, Jianjun; Almal, Arpit A; Chinnaiyan, Arul M

2009-02-01

The theory of Darwinian evolution is the fundamental keystones of modern biology. Late in the last century, computer scientists began adapting its principles, in particular natural selection, to complex computational challenges, leading to the emergence of evolutionary algorithms. The conceptual model of selective pressure and recombination in evolutionary algorithms allow scientists to efficiently search high dimensional space for solutions to complex problems. In the last decade, genetic programming has been developed and extensively applied for analysis of molecular data to classify cancer subtypes and characterize the mechanisms of cancer pathogenesis and development. This article reviews current successes using genetic programming and discusses its potential impact in cancer research and treatment in the near future.

The NASA Electronic Parts and Packaging (NEPP) Program: Insertion of New Electronics Technologies

NASA Technical Reports Server (NTRS)

LaBel, Kenneth A.; Sampson, Michael J.

2007-01-01

This viewgraph presentation gives an overview of NASA Electronic Parts and Packaging (NEPP) Program's new electronics technology trends. The topics include: 1) The Changing World of Radiation Testing of Memories; 2) Even Application-Specific Tests are Costly!; 3) Hypothetical New Technology Part Qualification Cost; 4) Where we are; 5) Approaching FPGAs as a More Than a "Part" for Reliability; 6) FPGAs Beget Novel Radiation Test Setups; 7) Understanding the Complex Radiation Data; 8) Tracking Packaging Complexity and Reliability for FPGAs; 9) Devices Supporting the FPGA Need to be Considered; 10) Summary of the New Electronic Technologies and Insertion into Flight Programs Workshop; and 11) Highlights of Panel Notes and Comments

A novel primary-specialist care collaborative demonstration project to improve the access and health care of medically complex patients.

PubMed

Siu, Henry Yu-Hin; Steward, Nicole; Peter, Jessica; Cooke, Laurel; Arnold, Donald M; Price, David

2017-09-01

Objective Medically complex patients experience fragmented health care compounded by long wait times. The MedREACH program was developed to improve access and overall system experience for medically complex patients. Program description MedREACH is a novel primary-tertiary care collaborative demonstration program that features community nursing outreach, community specialist outreach, and a multi-specialty consultation clinic. Methods All 179 patients, referring primary care clinicians, and specialists involved were eligible to participate. Patient and clinician feedback were elicited by feedback surveys. Process measures were evaluated by participant retrospective chart reviews. Community nursing outreach patients completed the Goal Attainment Scale. Results Forty-eight patients and 22 clinicians consented to the feedback survey. About 75% of patients were seen within 2 weeks of referral. Patients spent an average of 3, 1.63, and 1.2 visits with the nursing outreach, multi-specialty clinic, and specialist outreach, respectively. Patients indicated a better medical experience, health enablement, and goals attainment. Family physicians felt more supported in the community management of medically complex patients and, overall, physicians felt MedREACH could improve collaborative care for medically complex patients. Qualitative analysis of clinician responses identified the need for increased mental health services. Discussion MedREACH demonstrates a patient-centered link between primary and tertiary care that could improve health care access and overall experience.

Kennedy Space Center Director Update

NASA Image and Video Library

2014-03-06

CAPE CANAVERAL, Fla. - Community leaders, business executives, educators, and state and local government leaders were updated on NASA Kennedy Space Center programs and accomplishments during Center Director Bob Cabana’s Center Director Update at the Debus Center at the Kennedy Space Center Visitor Complex in Florida. An attendee talks with Trent Smith, program manager, and Tammy Belk, a program specialist, at the ISS Ground Processing and Research Office display. Attendees talked with Cabana and other senior Kennedy managers and visited displays featuring updates on Kennedy programs and projects, including International Space Station, Commercial Crew, Ground System Development and Operations, Launch Services, Center Planning and Development, Technology, KSC Swamp Works and NASA Education. The morning concluded with a tour of the new Space Shuttle Atlantis exhibit at the visitor complex. For more information, visit http://www.nasa.gov/kennedy. Photo credit: NASA/Daniel Casper

Computer aided reliability, availability, and safety modeling for fault-tolerant computer systems with commentary on the HARP program

NASA Technical Reports Server (NTRS)

Shooman, Martin L.

1991-01-01

Many of the most challenging reliability problems of our present decade involve complex distributed systems such as interconnected telephone switching computers, air traffic control centers, aircraft and space vehicles, and local area and wide area computer networks. In addition to the challenge of complexity, modern fault-tolerant computer systems require very high levels of reliability, e.g., avionic computers with MTTF goals of one billion hours. Most analysts find that it is too difficult to model such complex systems without computer aided design programs. In response to this need, NASA has developed a suite of computer aided reliability modeling programs beginning with CARE 3 and including a group of new programs such as: HARP, HARP-PC, Reliability Analysts Workbench (Combination of model solvers SURE, STEM, PAWS, and common front-end model ASSIST), and the Fault Tree Compiler. The HARP program is studied and how well the user can model systems using this program is investigated. One of the important objectives will be to study how user friendly this program is, e.g., how easy it is to model the system, provide the input information, and interpret the results. The experiences of the author and his graduate students who used HARP in two graduate courses are described. Some brief comparisons were made with the ARIES program which the students also used. Theoretical studies of the modeling techniques used in HARP are also included. Of course no answer can be any more accurate than the fidelity of the model, thus an Appendix is included which discusses modeling accuracy. A broad viewpoint is taken and all problems which occurred in the use of HARP are discussed. Such problems include: computer system problems, installation manual problems, user manual problems, program inconsistencies, program limitations, confusing notation, long run times, accuracy problems, etc.

RIP1 and RIP3 complex regulates radiation-induced programmed necrosis in glioblastoma.

PubMed

Das, Arabinda; McDonald, Daniel G; Dixon-Mah, Yaenette N; Jacqmin, Dustin J; Samant, Vikram N; Vandergrift, William A; Lindhorst, Scott M; Cachia, David; Varma, Abhay K; Vanek, Kenneth N; Banik, Naren L; Jenrette, Joseph M; Raizer, Jeffery J; Giglio, Pierre; Patel, Sunil J

2016-06-01

Radiation-induced necrosis (RN) is a relatively common side effect of radiation therapy for glioblastoma. However, the molecular mechanisms involved and the ways RN mechanisms differ from regulated cell death (apoptosis) are not well understood. Here, we compare the molecular mechanism of cell death (apoptosis or necrosis) of C6 glioma cells in both in vitro and in vivo (C6 othotopically allograft) models in response to low and high doses of X-ray radiation. Lower radiation doses were used to induce apoptosis, while high-dose levels were chosen to induce radiation necrosis. Our results demonstrate that active caspase-8 in this complex I induces apoptosis in response to low-dose radiation and inhibits necrosis by cleaving RIP1 and RI. When activation of caspase-8 was reduced at high doses of X-ray radiation, the RIP1/RIP3 necrosome complex II is formed. These complexes induce necrosis through the caspase-3-independent pathway mediated by calpain, cathepsin B/D, and apoptosis-inducing factor (AIF). AIF has a dual role in apoptosis and necrosis. At high doses, AIF promotes chromatinolysis and necrosis by interacting with histone H2AX. In addition, NF-κB, STAT-3, and HIF-1 play a crucial role in radiation-induced inflammatory responses embedded in a complex inflammatory network. Analysis of inflammatory markers in matched plasma and cerebrospinal fluid (CSF) isolated from in vivo specimens demonstrated the upregulation of chemokines and cytokines during the necrosis phase. Using RIP1/RIP3 kinase specific inhibitors (Nec-1, GSK'872), we also establish that the RIP1-RIP3 complex regulates programmed necrosis after either high-dose radiation or TNF-α-induced necrosis requires RIP1 and RIP3 kinases. Overall, our data shed new light on the relationship between RIP1/RIP3-mediated programmed necrosis and AIF-mediated caspase-independent programmed necrosis in glioblastoma.

Multidisciplinary approaches to climate change questions

USGS Publications Warehouse

Middleton, Beth A.; LePage, Ben A.

2011-01-01

Multidisciplinary approaches are required to address the complex environmental problems of our time. Solutions to climate change problems are good examples of situations requiring complex syntheses of ideas from a vast set of disciplines including science, engineering, social science, and the humanities. Unfortunately, most ecologists have narrow training, and are not equipped to bring their environmental skills to the table with interdisciplinary teams to help solve multidisciplinary problems. To address this problem, new graduate training programs and workshops sponsored by various organizations are providing opportunities for scientists and others to learn to work together in multidisciplinary teams. Two examples of training in multidisciplinary thinking include those organized by the Santa Fe Institute and Dahlem Workshops. In addition, many interdisciplinary programs have had successes in providing insight into climate change problems including the International Panel on Climate Change, the Joint North American Carbon Program, the National Academy of Science Research Grand Challenges Initiatives, and the National Academy of Science. These programs and initiatives have had some notable success in outlining some of the problems and solutions to climate change. Scientists who can offer their specialized expertise to interdisciplinary teams will be more successful in helping to solve the complex problems related to climate change.

Non-formal educator use of evaluation results.

PubMed

Baughman, Sarah; Boyd, Heather H; Franz, Nancy K

2012-08-01

Increasing demands for accountability in educational programming have resulted in increasing calls for program evaluation in educational organizations. Many organizations include conducting program evaluations as part of the job responsibilities of program staff. Cooperative Extension is a complex organization offering non-formal educational programs through land grant universities. Many Extension services require non-formal educational program evaluations be conducted by field-based Extension educators. Evaluation research has focused primarily on the efforts of professional, external evaluators. The work of program staff with many responsibilities including program evaluation has received little attention. This study examined how field based Extension educators (i.e. program staff) in four Extension services use the results of evaluations of programs that they have conducted themselves. Four types of evaluation use are measured and explored; instrumental use, conceptual use, persuasive use and process use. Results indicate that there are few programmatic changes as a result of evaluation findings among the non-formal educators surveyed in this study. Extension educators tend to use evaluation results to persuade others about the value of their programs and learn from the evaluation process. Evaluation use is driven by accountability measures with very little program improvement use as measured in this study. Practical implications include delineating accountability and program improvement tasks within complex organizations in order to align evaluation efforts and to improve the results of both. There is some evidence that evaluation capacity building efforts may be increasing instrumental use by educators evaluating their own programs. Copyright © 2011 Elsevier Ltd. All rights reserved.

Developing a robotic pancreas program: the Dutch experience

PubMed Central

Nota, Carolijn L.; Zwart, Maurice J.; Fong, Yuman; Hagendoorn, Jeroen; Hogg, Melissa E.; Koerkamp, Bas Groot; Besselink, Marc G.

2017-01-01

Robot-assisted surgery has been developed to overcome limitations of conventional laparoscopy aiming to further optimize minimally invasive surgery. Despite the fact that robotics already have been widely adopted in urology, gynecology, and several gastro-intestinal procedures, like colorectal surgery, pancreatic surgery lags behind. Due to the complex nature of the procedure, surgeons probably have been hesitant to apply minimally invasive techniques in pancreatic surgery. Nevertheless, the past few years pancreatic surgery has been catching up. An increasing number of procedures are being performed laparoscopically and robotically, despite it being a highly complex procedure with high morbidity and mortality rates. Since the complex nature and extensiveness of the procedure, the start of a robotic pancreatic program should be properly prepared and should comply with several conditions within high-volume centers. Robotic training plays a significant role in the preparation. In this review we discuss the different aspects of preparation when working towards the start of a robotic pancreas program against the background of our nationwide experience in the Netherlands. PMID:29078666

Developing a robotic pancreas program: the Dutch experience.

PubMed

Nota, Carolijn L; Zwart, Maurice J; Fong, Yuman; Hagendoorn, Jeroen; Hogg, Melissa E; Koerkamp, Bas Groot; Besselink, Marc G; Molenaar, I Quintus

2017-01-01

Robot-assisted surgery has been developed to overcome limitations of conventional laparoscopy aiming to further optimize minimally invasive surgery. Despite the fact that robotics already have been widely adopted in urology, gynecology, and several gastro-intestinal procedures, like colorectal surgery, pancreatic surgery lags behind. Due to the complex nature of the procedure, surgeons probably have been hesitant to apply minimally invasive techniques in pancreatic surgery. Nevertheless, the past few years pancreatic surgery has been catching up. An increasing number of procedures are being performed laparoscopically and robotically, despite it being a highly complex procedure with high morbidity and mortality rates. Since the complex nature and extensiveness of the procedure, the start of a robotic pancreatic program should be properly prepared and should comply with several conditions within high-volume centers. Robotic training plays a significant role in the preparation. In this review we discuss the different aspects of preparation when working towards the start of a robotic pancreas program against the background of our nationwide experience in the Netherlands.

Complexity Bounds for Quantum Computation

DTIC Science & Technology

2007-06-22

Programs Trustees of Boston University Boston, MA 02215 - Complexity Bounds for Quantum Computation REPORT DOCUMENTATION PAGE 18. SECURITY CLASSIFICATION...Complexity Bounds for Quantum Comp[utation Report Title ABSTRACT This project focused on upper and lower bounds for quantum computability using constant...classical computation models, particularly emphasizing new examples of where quantum circuits are more powerful than their classical counterparts. A second

MASPROP- MASS PROPERTIES OF A RIGID STRUCTURE

NASA Technical Reports Server (NTRS)

Hull, R. A.

1994-01-01

The computer program MASPROP was developed to rapidly calculate the mass properties of complex rigid structural systems. This program's basic premise is that complex systems can be adequately described by a combination of basic elementary structural shapes. Thirteen widely used basic structural shapes are available in this program. They are as follows: Discrete Mass, Cylinder, Truncated Cone, Torus, Beam (arbitrary cross section), Circular Rod (arbitrary cross section), Spherical Segment, Sphere, Hemisphere, Parallelepiped, Swept Trapezoidal Panel, Symmetric Trapezoidal Panels, and a Curved Rectangular Panel. MASPROP provides a designer with a simple technique that requires minimal input to calculate the mass properties of a complex rigid structure and should be useful in any situation where one needs to calculate the center of gravity and moments of inertia of a complex structure. Rigid body analysis is used to calculate mass properties. Mass properties are calculated about component axes that have been rotated to be parallel to the system coordinate axes. Then the system center of gravity is calculated and the mass properties are transferred to axes through the system center of gravity by using the parallel axis theorem. System weight, moments of inertia about the system origin, and the products of inertia about the system center of mass are calculated and printed. From the information about the system center of mass the principal axes of the system and the moments of inertia about them are calculated and printed. The only input required is simple geometric data describing the size and location of each element and the respective material density or weight of each element. This program is written in FORTRAN for execution on a CDC 6000 series computer with a central memory requirement of approximately 62K (octal) of 60 bit words. The development of this program was completed in 1978.

KSC-2012-3046

NASA Image and Video Library

2012-05-23

CAPE CANAVERAL, Fla. – A manatee relaxes in the Indian River near the NASA Railroad’s Jay Jay Railroad Bridge north of Launch Complex 39 at NASA’s Kennedy Space Center in Florida. The manatee was spotted by a cameraman on hand to photograph a NASA Railroad train on its way to the Florida East Coast Railway interchange in Titusville, Fla., where the train’s helium tank cars, a liquid oxygen tank car, and a liquid hydrogen dewar or tank car will be transferred for delivery to the SpaceX engine test complex outside McGregor, Texas. The railroad cars were needed in support of the Space Shuttle Program but currently are not in use by NASA following the completion of the program in 2011. Originally, the tankers belonged to the U.S. Bureau of Mines. At the peak of the shuttle program, there were approximately 30 cars in the fleet. About half the cars were returned to the bureau as launch activity diminished. Five tank cars are being loaned to SpaceX and repurposed to support their engine tests in Texas. Eight cars previously were shipped to California on loan to support the SpaceX Falcon 9 rocket launches from Space Launch Complex-4 on Vandenberg Air Force Base. SpaceX already has three helium tank cars previously used for the shuttle program at Space Launch Complex-40 on Cape Canaveral Air Force Station in Florida. For more information, visit http://www.nasa.gov/spacex. Photo credit: NASA/Jim Grossmann

KSC-2012-3044

NASA Image and Video Library

2012-05-23

CAPE CANAVERAL, Fla. – A manatee relaxes in the Indian River near the NASA Railroad’s Jay Jay Railroad Bridge north of Launch Complex 39 at NASA’s Kennedy Space Center in Florida. The manatee was spotted by a cameraman on hand to photograph a NASA Railroad train on its way to the Florida East Coast Railway interchange in Titusville, Fla., where the train’s helium tank cars, a liquid oxygen tank car, and a liquid hydrogen dewar or tank car will be transferred for delivery to the SpaceX engine test complex outside McGregor, Texas. The railroad cars were needed in support of the Space Shuttle Program but currently are not in use by NASA following the completion of the program in 2011. Originally, the tankers belonged to the U.S. Bureau of Mines. At the peak of the shuttle program, there were approximately 30 cars in the fleet. About half the cars were returned to the bureau as launch activity diminished. Five tank cars are being loaned to SpaceX and repurposed to support their engine tests in Texas. Eight cars previously were shipped to California on loan to support the SpaceX Falcon 9 rocket launches from Space Launch Complex-4 on Vandenberg Air Force Base. SpaceX already has three helium tank cars previously used for the shuttle program at Space Launch Complex-40 on Cape Canaveral Air Force Station in Florida. For more information, visit http://www.nasa.gov/spacex. Photo credit: NASA/Jim Grossmann

KSC-2012-3043

NASA Image and Video Library

2012-05-23

CAPE CANAVERAL, Fla. – A manatee swims in the Indian River near the NASA Railroad’s Jay Jay Railroad Bridge north of Launch Complex 39 at NASA’s Kennedy Space Center in Florida. The manatee was spotted by a cameraman on hand to photograph a NASA Railroad train on its way to the Florida East Coast Railway interchange in Titusville, Fla., where the train’s helium tank cars, a liquid oxygen tank car, and a liquid hydrogen dewar or tank car will be transferred for delivery to the SpaceX engine test complex outside McGregor, Texas. The railroad cars were needed in support of the Space Shuttle Program but currently are not in use by NASA following the completion of the program in 2011. Originally, the tankers belonged to the U.S. Bureau of Mines. At the peak of the shuttle program, there were approximately 30 cars in the fleet. About half the cars were returned to the bureau as launch activity diminished. Five tank cars are being loaned to SpaceX and repurposed to support their engine tests in Texas. Eight cars previously were shipped to California on loan to support the SpaceX Falcon 9 rocket launches from Space Launch Complex-4 on Vandenberg Air Force Base. SpaceX already has three helium tank cars previously used for the shuttle program at Space Launch Complex-40 on Cape Canaveral Air Force Station in Florida. For more information, visit http://www.nasa.gov/spacex. Photo credit: NASA/Jim Grossmann

KSC-2012-3045

NASA Image and Video Library

2012-05-23

CAPE CANAVERAL, Fla. – Manatees relax in the Indian River near the NASA Railroad’s Jay Jay Railroad Bridge north of Launch Complex 39 at NASA’s Kennedy Space Center in Florida. The manatees were spotted by a cameraman on hand to photograph a NASA Railroad train on its way to the Florida East Coast Railway interchange in Titusville, Fla., where the train’s helium tank cars, a liquid oxygen tank car, and a liquid hydrogen dewar or tank car will be transferred for delivery to the SpaceX engine test complex outside McGregor, Texas. The railroad cars were needed in support of the Space Shuttle Program but currently are not in use by NASA following the completion of the program in 2011. Originally, the tankers belonged to the U.S. Bureau of Mines. At the peak of the shuttle program, there were approximately 30 cars in the fleet. About half the cars were returned to the bureau as launch activity diminished. Five tank cars are being loaned to SpaceX and repurposed to support their engine tests in Texas. Eight cars previously were shipped to California on loan to support the SpaceX Falcon 9 rocket launches from Space Launch Complex-4 on Vandenberg Air Force Base. SpaceX already has three helium tank cars previously used for the shuttle program at Space Launch Complex-40 on Cape Canaveral Air Force Station in Florida. For more information, visit http://www.nasa.gov/spacex. Photo credit: NASA/Jim Grossmann

KSC-2012-3040a

NASA Image and Video Library

2012-05-23

CAPE CANAVERAL, Fla. – Bubbles form around a dolphin splashing in the Indian River near the NASA Railroad’s Jay Jay Railroad Bridge north of Launch Complex 39 at NASA’s Kennedy Space Center in Florida. The dolphin was spotted by a cameraman on hand to photograph a NASA Railroad train on its way to the Florida East Coast Railway interchange in Titusville, Fla., where the train’s helium tank cars, a liquid oxygen tank car, and a liquid hydrogen dewar or tank car will be transferred for delivery to the SpaceX engine test complex outside McGregor, Texas. The railroad cars were needed in support of the Space Shuttle Program but currently are not in use by NASA following the completion of the program in 2011. Originally, the tankers belonged to the U.S. Bureau of Mines. At the peak of the shuttle program, there were approximately 30 cars in the fleet. About half the cars were returned to the bureau as launch activity diminished. Five tank cars are being loaned to SpaceX and repurposed to support their engine tests in Texas. Eight cars previously were shipped to California on loan to support the SpaceX Falcon 9 rocket launches from Space Launch Complex-4 on Vandenberg Air Force Base. SpaceX already has three helium tank cars previously used for the shuttle program at Space Launch Complex-40 on Cape Canaveral Air Force Station in Florida. For more information, visit http://www.nasa.gov/spacex. Photo credit: NASA/Jim Grossmann

KSC-2012-3041a

NASA Image and Video Library

2012-05-23

CAPE CANAVERAL, Fla. – A dolphin plays in the Indian River near the NASA Railroad’s Jay Jay Railroad Bridge north of Launch Complex 39 at NASA’s Kennedy Space Center in Florida. The dolphin was spotted by a cameraman on hand to photograph a NASA Railroad train on its way to the Florida East Coast Railway interchange in Titusville, Fla., where the train’s helium tank cars, a liquid oxygen tank car, and a liquid hydrogen dewar or tank car will be transferred for delivery to the SpaceX engine test complex outside McGregor, Texas. The railroad cars were needed in support of the Space Shuttle Program but currently are not in use by NASA following the completion of the program in 2011. Originally, the tankers belonged to the U.S. Bureau of Mines. At the peak of the shuttle program, there were approximately 30 cars in the fleet. About half the cars were returned to the bureau as launch activity diminished. Five tank cars are being loaned to SpaceX and repurposed to support their engine tests in Texas. Eight cars previously were shipped to California on loan to support the SpaceX Falcon 9 rocket launches from Space Launch Complex-4 on Vandenberg Air Force Base. SpaceX already has three helium tank cars previously used for the shuttle program at Space Launch Complex-40 on Cape Canaveral Air Force Station in Florida. For more information, visit http://www.nasa.gov/spacex. Photo credit: NASA/Jim Grossmann

KSC-2012-3042

NASA Image and Video Library

2012-05-23

CAPE CANAVERAL, Fla. – A dolphin swims in the Indian River near the NASA Railroad’s Jay Jay Railroad Bridge north of Launch Complex 39 at NASA’s Kennedy Space Center in Florida. The dolphin was spotted by a cameraman on hand to photograph a NASA Railroad train on its way to the Florida East Coast Railway interchange in Titusville, Fla., where the train’s helium tank cars, a liquid oxygen tank car, and a liquid hydrogen dewar or tank car will be transferred for delivery to the SpaceX engine test complex outside McGregor, Texas. The railroad cars were needed in support of the Space Shuttle Program but currently are not in use by NASA following the completion of the program in 2011. Originally, the tankers belonged to the U.S. Bureau of Mines. At the peak of the shuttle program, there were approximately 30 cars in the fleet. About half the cars were returned to the bureau as launch activity diminished. Five tank cars are being loaned to SpaceX and repurposed to support their engine tests in Texas. Eight cars previously were shipped to California on loan to support the SpaceX Falcon 9 rocket launches from Space Launch Complex-4 on Vandenberg Air Force Base. SpaceX already has three helium tank cars previously used for the shuttle program at Space Launch Complex-40 on Cape Canaveral Air Force Station in Florida. For more information, visit http://www.nasa.gov/spacex. Photo credit: NASA/Jim Grossmann

75 FR 51047 - Notice of Receipt of a Pesticide Petition Filed for Residues of Complex Polymeric Polyhydroxy...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-18

... Adams, Biopesticides and Pollution Prevention Division (7511P), Office of Pesticide Programs... McDavit, Acting Director, Biopesticides and Pollution Prevention Division, Office of Pesticide Programs...

Paediatric patient navigation models of care in Canada: An environmental scan.

PubMed

Luke, Alison; Doucet, Shelley; Azar, Rima

2018-05-01

(1) To provide other organizations with useful information when implementing paediatric navigation programs and (2) to inform the implementation of a navigation care centre in New Brunswick for children with complex health conditions. This environmental scan consisted of a literature review of published and grey literature for paediatric patient navigation programs across Canada. Additional programs were found following discussions with program coordinators and navigators. Interviews were conducted with key staff from each program and included questions related to patient condition; target population and location; method delivery; navigator background; and navigator roles. Data analysis included analysis of interviews and identification of common themes across the different programs. We interviewed staff from 19 paediatric navigation programs across Canada. Programs varied across a number of different themes, including: condition and disease type, program location (e.g., hospital or clinic), navigator background (e.g., registered nurse or peer/lay navigator) and method of delivery (e.g., phone or face-to-face). Overall, navigator roles are similar across all programs, including advocacy, education, support and assistance in accessing resources from both within and outside the health care system. This scan offers a road map of Canadian paediatric navigation programs. Knowledge learned from this scan will inform stakeholders who are either involved in the delivery of paediatric patient navigation programs or planning to implement such a program. Specifically, our scan informed the development of a navigation centre for children with complex health conditions in New Brunswick.

Farmer Participation in U.S. Farm Bill Conservation Programs

NASA Astrophysics Data System (ADS)

Reimer, Adam P.; Prokopy, Linda S.

2014-02-01

Conservation policy in agricultural systems in the United States relies primarily on voluntary action by farmers. Federal conservation programs, including the Environmental Quality Incentives Program, offer incentives, both financial and technical, to farmers in exchange for adoption of conservation practices. Understanding motivations for (as well as barriers to) participation in voluntary programs is important for the design of future policy and effective outreach. While a significant literature has explored motivations and barriers to conservation practice adoption and participation in single programs, few studies in the U.S. context have explored general participation by farmers in one place and time. A mixed-methods research approach was utilized to explore farmer participation in all U.S. Farm Bill programs in Indiana. Current and past program engagement was high, with nearly half of survey respondents reporting participation in at least one program. Most participants had experience with the Conservation Reserve Program, with much lower participation rates in other programs. Most interview participants who had experience in programs were motivated by the environmental benefits of practices, with incentives primarily serving to reduce the financial and technical barriers to practice adoption. The current policy arrangement, which offers multiple policy approaches to conservation, offers farmers with different needs and motivations a menu of options. However, evidence suggests that the complexity of the system may be a barrier that prevents participation by farmers with scarce time or resources. Outreach efforts should focus on increasing awareness of program options, while future policy must balance flexibility of programs with complexity.

Liability for Personal Injury Caused by Defective Medical Computer Programs

PubMed Central

Brannigan, Vincent M.

1980-01-01

Defective medical computer programs can cause personal injury. Financial responsibility for the injury under tort law will turn on several factors: whether the program is a product or a service, what types of defect exist in the product, and who produced the program. The factors involved in making these decisions are complex, but knowledge of the relevant issues can assist computer personnel in avoiding liability.

Streamlining DOD Acquisitions: Balancing Schedule with Complexity

DTIC Science & Technology

2006-09-01

from them has a distinct industrial flavor: streamlined processes, benchmarking, and business models . The requirements generation com- munity led by... model ), and the Department of the Navy assumed program lead. [Stable Program Inputs (-)] By 1984, the program goals included delivery of 913 V-22...they subsequently specified a crew of two. [Stable Program Input (-)] The contractor team won in a “fly-off” solely via modeling and simulation

The method of complex characteristics for design of transonic blade sections

NASA Technical Reports Server (NTRS)

Bledsoe, M. R.

1986-01-01

A variety of computational methods were developed to obtain shockless or near shockless flow past two-dimensional airfoils. The approach used was the method of complex characteristics, which determines smooth solutions to the transonic flow equations based on an input speed distribution. General results from fluid mechanics are presented. An account of the method of complex characteristics is given including a description of the particular spaces and coordinates, conformal transformations, and numerical procedures that are used. The operation of the computer program COMPRES is presented along with examples of blade sections designed with the code. A user manual is included with a glossary to provide additional information which may be helpful. The computer program in Fortran, including numerous comment cards is listed.

Behavior of complex mixtures in aquatic environments: a synthesis of PNL ecological research

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fickeisen, D.H.; Vaughan, B.E.

1984-06-01

The term complex mixture has been recently applied to energy-related process streams, products and wastes that typically contain hundreds or thousands of individual organic compounds, like petroleum or synthetic fuel oils; but it is more generally applicable. A six-year program of ecological research has focused on four areas important to understanding the environmental behavior of complex mixtures: physicochemical variables, individual organism responses, ecosystems-level determinations, and metabolism. Of these areas, physicochemical variables and organism responses were intensively studied; system-level determinations and metabolism represent more recent directions. Chemical characterization was integrated throughout all areas of the program, and state-of-the-art methods were applied.more » 155 references, 35 figures, 4 tables.« less

Aerial views of construction on the RLV hangar at the Shuttle Landing Facility

NASA Technical Reports Server (NTRS)

1999-01-01

Looking southwest, this view shows ongoing construction of a multi-purpose hangar, which is part of the $8 million Reusable Launch Vehicle (RLV) Support Complex at Kennedy Space Center. Edging the construction is Sharkey Road, which parallels the landing strip of the Shuttle Landing Facility nearby. The RLV complex will include facilities for related ground support equipment and administrative/ technical support. It will be available to accommodate the Space Shuttle; the X-34 RLV technology demonstrator; the L-1011 carrier aircraft for Pegasus and X-34; and other RLV and X-vehicle programs. The complex is jointly funded by the Spaceport Florida Authority, NASA's Space Shuttle Program and KSC. The facility will be operational in early 2000.

Flexible Generation of Kalman Filter Code

NASA Technical Reports Server (NTRS)

Richardson, Julian; Wilson, Edward

2006-01-01

Domain-specific program synthesis can automatically generate high quality code in complex domains from succinct specifications, but the range of programs which can be generated by a given synthesis system is typically narrow. Obtaining code which falls outside this narrow scope necessitates either 1) extension of the code generator, which is usually very expensive, or 2) manual modification of the generated code, which is often difficult and which must be redone whenever changes are made to the program specification. In this paper, we describe adaptations and extensions of the AUTOFILTER Kalman filter synthesis system which greatly extend the range of programs which can be generated. Users augment the input specification with a specification of code fragments and how those fragments should interleave with or replace parts of the synthesized filter. This allows users to generate a much wider range of programs without their needing to modify the synthesis system or edit generated code. We demonstrate the usefulness of the approach by applying it to the synthesis of a complex state estimator which combines code from several Kalman filters with user-specified code. The work described in this paper allows the complex design decisions necessary for real-world applications to be reflected in the synthesized code. When executed on simulated input data, the generated state estimator was found to produce comparable estimates to those produced by a handcoded estimator

Generalized Symbolic Execution for Model Checking and Testing

NASA Technical Reports Server (NTRS)

Khurshid, Sarfraz; Pasareanu, Corina; Visser, Willem; Kofmeyer, David (Technical Monitor)

2003-01-01

Modern software systems, which often are concurrent and manipulate complex data structures must be extremely reliable. We present a novel framework based on symbolic execution, for automated checking of such systems. We provide a two-fold generalization of traditional symbolic execution based approaches: one, we define a program instrumentation, which enables standard model checkers to perform symbolic execution; two, we give a novel symbolic execution algorithm that handles dynamically allocated structures (e.g., lists and trees), method preconditions (e.g., acyclicity of lists), data (e.g., integers and strings) and concurrency. The program instrumentation enables a model checker to automatically explore program heap configurations (using a systematic treatment of aliasing) and manipulate logical formulae on program data values (using a decision procedure). We illustrate two applications of our framework: checking correctness of multi-threaded programs that take inputs from unbounded domains with complex structure and generation of non-isomorphic test inputs that satisfy a testing criterion. Our implementation for Java uses the Java PathFinder model checker.

Multitasking runtime systems for the Cedar Multiprocessor

DOE Office of Scientific and Technical Information (OSTI.GOV)

Guzzi, M.D.

1986-07-01

The programming of a MIMD machine is more complex than for SISD and SIMD machines. The multiple computational resources of the machine must be made available to the programming language compiler and to the programmer so that multitasking programs may be written. This thesis will explore the additional complexity of programming a MIMD machine, the Cedar Multiprocessor specifically, and the multitasking runtime system necessary to provide multitasking resources to the user. First, the problem will be well defined: the Cedar machine, its operating system, the programming language, and multitasking concepts will be described. Second, a solution to the problem, calledmore » macrotasking, will be proposed. This solution provides multitasking facilities to the programmer at a very coarse level with many visible machine dependencies. Third, an alternate solution, called microtasking, will be proposed. This solution provides multitasking facilities of a much finer grain. This solution does not depend so rigidly on the specific architecture of the machine. Finally, the two solutions will be compared for effectiveness. 12 refs., 16 figs.« less

Employee Participation Programs: Considerations for the School Site. Studies in Collective Bargaining.

ERIC Educational Resources Information Center

National Education Association, Washington, DC. Research Div.

Site-based decisionmaking programs offer important opportunities for school systems; however, the risks involved are significant and the decision to embrace the concept at the local level is a highly complex one. With site-based decisionmaking programs, teachers are directly involved in making decisions that affect the whole school, not merely…

Use of a Computer Language in Teaching Dynamic Programming. Final Report.

ERIC Educational Resources Information Center

Trimble, C. J.; And Others

Most optimization problems of any degree of complexity must be solved using a computer. In the teaching of dynamic programing courses, it is often desirable to use a computer in problem solution. The solution process involves conceptual formulation and computational Solution. Generalized computer codes for dynamic programing problem solution…

"2 + 2 + 2" Articulated Programs: Benefits for Educators and Students.

ERIC Educational Resources Information Center

Stanley, Patricia

1992-01-01

In Los Angeles, a secondary regional occupational program, a community college, and a university department developed an articulated 2+2+2 program in fashion merchandising that opens doors to college degrees for students who would otherwise not participate in college prep. The complexities of negotiating agreements are outweighed by the benefits…

Planning Effective Educational Programs for Adult Learners

ERIC Educational Resources Information Center

Shi, Hong

2017-01-01

Educational program planning is a complex ongoing process and planners should reflect on and consider for all of the involved factors, context, and people. The purpose of this study is to analyze how to plan effective educational programs for adult learners. Adult education is a developmental process and interacts with broad social events. Adult…

Developing an International Distance Education Program: A Blended Learning Approach

ERIC Educational Resources Information Center

Mathur, Ravisha; Oliver, Lisa

2007-01-01

Building a dynamic international distance education program can be a complex operation. The purpose of this paper is to discuss a model for global learning that utilizes a blended learning approach. This paper will describe how a blended learning approach was implemented in an international instructional technology Master's program to the benefit…

Programming Pluralism: Using Learning Analytics to Detect Patterns in the Learning of Computer Programming

ERIC Educational Resources Information Center

Blikstein, Paulo; Worsley, Marcelo; Piech, Chris; Sahami, Mehran; Cooper, Steven; Koller, Daphne

2014-01-01

New high-frequency, automated data collection and analysis algorithms could offer new insights into complex learning processes, especially for tasks in which students have opportunities to generate unique open-ended artifacts such as computer programs. These approaches should be particularly useful because the need for scalable project-based and…

Do Premarital Education Programs Really Work? A Meta-Analytic Study

ERIC Educational Resources Information Center

Fawcett, Elizabeth B.; Hawkins, Alan J.; Blanchard, Victoria L.; Carroll, Jason S.

2010-01-01

Previous studies (J. S. Carroll & W. J. Doherty, 2003) have asserted that premarital education programs have a positive effect on program participants. Using meta-analytic methods of current best practices to look across the entire body of published and unpublished evaluation research on premarital education, we found a more complex pattern of…

Addressing the Mathematics-Specific Needs of Beginning Mathematics Teachers

ERIC Educational Resources Information Center

Britton, Edward

2012-01-01

Beginning mathematics teachers at the secondary level (middle and high school grades) have mathematics-specific needs that induction programs should address more substantially. However, a number of issues in how programs can accomplish this are more complex than often framed in discussions occurring in the induction programs and the field of…

Conceptual Frameworks in Undergraduate Nursing Curricula: Report of a National Survey.

ERIC Educational Resources Information Center

McEwen, Melanie; Brown, Sandra C.

2002-01-01

Responses from 300 accredited nursing schools indicated that they used eclectic conceptual frameworks for curriculum; the most common component was the nursing process. Associate degree programs were more likely to use simple-to-complex organization. Diploma programs were more likely to use the medical model than baccalaureate programs. Frameworks…

A Social Work Program's Experience in Teaching about Race in the Curriculum

ERIC Educational Resources Information Center

Phan, Phu; Vugia, Holly; Wright, Paul; Woods, Dianne Rush; Chu, Mayling; Jones, Terry

2009-01-01

Teaching about race, racism, and oppression presents higher education programs with complex challenges. This article reports on the experiences of a new MSW program in designing a gateway "race, gender, and inequality" course. Embracing a theoretical base of culturally competent practice and solutions to the inherent difficulties of discussing…

Developing Computer Programming Concepts and Skills via Technology-Enriched Language-Art Projects: A Case Study

ERIC Educational Resources Information Center

Lee, Young-Jin

2010-01-01

Teaching computer programming to young children has been considered difficult because of its abstract and complex nature. The objectives of this study are (1) to investigate whether an innovative educational technology tool called Scratch could enable young children to learn abstract knowledge of computer programming while creating multimedia…

Using System Dynamics as an Evaluation Tool: Experience from a Demonstration Program

ERIC Educational Resources Information Center

Fredericks, Kimberly A.; Deegan, Michael; Carman, Joanne G.

2008-01-01

Evaluators are often faced with many challenges in the design and implementation of a program's evaluation. Because programs are entangled in complex networks of structures and stakeholders, they can be challenging to understand, and they often pose issues of competing and conflicting goals. However, by using a systems mapping approach to…

Impact of Augmented Reality on Programming Language Learning: Efficiency and Perception

ERIC Educational Resources Information Center

Teng, Chin-Hung; Chen, Jr-Yi; Chen, Zhi-Hong

2018-01-01

Although the learning of programming language is critical in science and technology education, it might be difficult for some students, especially novices. One possible reason might be the fact that programming language, especially for three-dimensional (3D) applications, is too complex and abstract for these students to understand. Programming…

Pair Programming and LSs in Computing Education: Its Impact on Students' Performances

ERIC Educational Resources Information Center

Hui, Tie Hui; Umar, Irfan Naufal

2011-01-01

Learning to programme requires complex cognitive skills that computing students find it arduous in comprehension. PP (pair programming) is an intensive style of programme cooperation where two people working together in resolving programming scenarios. It begins to draw the interests of educators as a teaching approach to facilitate learning and…

Supporting Minority-Serving Institutions in Their Program Improvement Efforts: A Responsive Technical Assistance Approach

ERIC Educational Resources Information Center

Bay, Mary; Lopez-Reyna, Norma A.; Guillory, Barbara L.

2012-01-01

To reform a special education teacher preparation program can be gratifying, difficult, complex, political, and urgently needed. The Monarch Center, a federally funded technical assistance center, was established to guide and support minority-serving institutions in their efforts to improve their teacher preparation programs. Four guidelines…

Postsecondary Education for Students with Intellectual Disability (ID): Complex Layers

ERIC Educational Resources Information Center

Thoma, Colleen A.

2013-01-01

This phenomenological research study investigated nine postsecondary programs for youth and young adults with disabilities to determine the range of supports and services provided as well as the program development process. Each program had unique features and components and those differences were typically the result of the mission, values,…

A mixed integer program to model spatial wildfire behavior and suppression placement decisions

Treesearch

Erin J. Belval; Yu Wei; Michael Bevers

2015-01-01

Wildfire suppression combines multiple objectives and dynamic fire behavior to form a complex problem for decision makers. This paper presents a mixed integer program designed to explore integrating spatial fire behavior and suppression placement decisions into a mathematical programming framework. Fire behavior and suppression placement decisions are modeled using...

Teacher Responses to Participation in Hawaii's Kahua Induction Program

ERIC Educational Resources Information Center

Thigpen, Rebecca E.

2011-01-01

This qualitative, phenomenological study investigated teachers' responses to participation in the Kahua Induction Program for new and new-to-district public school teachers in Hawaii. Nine teachers were interviewed who had participated in the program for at least one year in the West Hawaii Complex Area on the island of Hawaii. Long, in-depth…

Mentoring Program Practices and Effectiveness.

ERIC Educational Resources Information Center

Johnson, Amy W.; Sullivan, Judith A.

1995-01-01

Philadelphia's Sponsor-a-Scholar program pairs high school students with adults who guide them in preparing for the future. The program shows that there is little certainty about what constitutes best practice; that the complex task of mentoring requires a gamut of skills; and that support services for both mentors and proteges are essential. (SK)

DCP Leading NIH Glycoscience Common Fund Program; Funding Opportunities Open | Division of Cancer Prevention

Cancer.gov

NCI's Division of Cancer Prevention is a leading participant for a key initiative in the National Institutes of Health (NIH) Glycoscience Common Fund program. This program supports development of accessible and affordable new tools and technologies for studying the role complex carbohydrates in health and disease. |

Dynamic Learning Objects to Teach Java Programming Language

ERIC Educational Resources Information Center

Narasimhamurthy, Uma; Al Shawkani, Khuloud

2010-01-01

This article describes a model for teaching Java Programming Language through Dynamic Learning Objects. The design of the learning objects was based on effective learning design principles to help students learn the complex topic of Java Programming. Visualization was also used to facilitate the learning of the concepts. (Contains 1 figure and 2…

A Term Project in Visual Basic: The Downhill Snowboard Shop

ERIC Educational Resources Information Center

Simkin, Mark G.

2007-01-01

Most commercial programming applications are considerably more complex than the end-of-chapter exercises found in programming textbooks. This case addresses this problem by requiring the students in entry-level Visual Basic programming classes to create an application that helps users order ski equipment from a retailer. For convenience, the forms…

The application of dynamic programming in production planning

NASA Astrophysics Data System (ADS)

Wu, Run

2017-05-01

Nowadays, with the popularity of the computers, various industries and fields are widely applying computer information technology, which brings about huge demand for a variety of application software. In order to develop software meeting various needs with most economical cost and best quality, programmers must design efficient algorithms. A superior algorithm can not only soul up one thing, but also maximize the benefits and generate the smallest overhead. As one of the common algorithms, dynamic programming algorithms are used to solving problems with some sort of optimal properties. When solving problems with a large amount of sub-problems that needs repetitive calculations, the ordinary sub-recursive method requires to consume exponential time, and dynamic programming algorithm can reduce the time complexity of the algorithm to the polynomial level, according to which we can conclude that dynamic programming algorithm is a very efficient compared to other algorithms reducing the computational complexity and enriching the computational results. In this paper, we expound the concept, basic elements, properties, core, solving steps and difficulties of the dynamic programming algorithm besides, establish the dynamic programming model of the production planning problem.

KSC-2013-3517

NASA Image and Video Library

2013-09-09

CAPE CANAVERAL, Fla. -- At the Kennedy Space Center Visitor Complex in Florida, officials pose at the site where a Shuttle Program time capsule has been secured vault within the walls of the Space Shuttle Atlantis home at the Kennedy Space Center Visitor Complex. From the left are: Pete Nickolenko, deputy director of NASA Ground Processing at Kennedy, Patty Stratton of Abacus Technology, currently program manager for the Information Management Communications Support Contract. During the Shuttle Program she was deputy director of Ground Operations for NASA's Space Program Operations Contractor, United Space Alliance, Rita Wilcoxon, NASA's now retired director of Shuttle Processing, Bob Cabana, director of the Kennedy Space Center and George Jacobs, deputy director of Center Operations, who was manager of the agency's Shuttle Transition and Retirement Project Office. The time capsule, containing artifacts and other memorabilia associated with the history of the program is designated to be opened on the 50th anniversary of the shuttle's final landing, STS-135. The new $100 million "Space Shuttle Atlantis" facility includes interactive exhibits that tell the story of the 30-year Space Shuttle Program and highlight the future of space exploration. Photo credit: NASA/Jim Grossmann

AN ADVANCED SYSTEM FOR POLLUTION PREVENTION IN CHEMICAL COMPLEXES

EPA Science Inventory

One important accomplishment is that the system will give process engineers interactively and simultaneously use of programs for total cost analysis, life cycle assessment and sustainability metrics to provide direction for the optimal chemical complex analysis pro...

On the writing of programming systems for spacecraft computers.

NASA Technical Reports Server (NTRS)

Mathur, F. P.; Rohr, J. A.

1972-01-01

Consideration of the systems designed to generate programs for the increasingly complex digital computers being used on board unmanned deep-space probes. Such programming systems must accommodate the special-purpose features incorporated in the hardware. The use of higher-level language facilities in the programming system can significantly simplify the task. Computers for Mariner and for the Outer Planets Grand Tour are briefly described, as well as their programming systems. Aspects of the higher level languages are considered.

Some programming techniques for increasing program versatility and efficiency on CDC equipment

NASA Technical Reports Server (NTRS)

Tiffany, S. H.; Newsom, J. R.

1978-01-01

Five programming techniques used to decrease core and increase program versatility and efficiency are explained. The techniques are: (1) dynamic storage allocation, (2) automatic core-sizing and core-resizing, (3) matrix partitioning, (4) free field alphanumeric reads, and (5) incorporation of a data complex. The advantages of these techniques and the basic methods for employing them are explained and illustrated. Several actual program applications which utilize these techniques are described as examples.

An Amazing Medical Discovery! A Comprehensive Neighborhood Quality of Life Enrichment Program. An Intensive Prevention Program To Address the Social Causes of Individual and Community Pathology in an Inner-City Neighborhood. Revised.

ERIC Educational Resources Information Center

Miami-Dade Community Coll., FL. Medical Center Campus.

In 1991, Miami-Dade Community College (MDCC) developed a proposal for the Comprehensive Neighborhood Quality of Life Enrichment Program, a program to be based on the principles of holism, prevention, and community synergy, focusing on the treatment of individuals with many, complex, and "all-at-once" needs. The program will operate in a poor…

Reachability Maps for In Situ Operations

NASA Technical Reports Server (NTRS)

Deen, Robert G.; Leger, Patrick C.; Robinson, Matthew L.; Bonitz, Robert G.

2013-01-01

This work covers two programs that accomplish the same goal: creation of a "reachability map" from stereo imagery that tells where operators of a robotic arm can reach or touch the surface, and with which instruments. The programs are "marsreach" (for MER) and "phxreach." These programs make use of the planetary image geometry (PIG) library. However, unlike the other programs, they are not multi-mission. Because of the complexity of arm kinematics, the programs are specific to each mission.

STARS: An integrated general-purpose finite element structural, aeroelastic, and aeroservoelastic analysis computer program

NASA Technical Reports Server (NTRS)

Gupta, Kajal K.

1991-01-01

The details of an integrated general-purpose finite element structural analysis computer program which is also capable of solving complex multidisciplinary problems is presented. Thus, the SOLIDS module of the program possesses an extensive finite element library suitable for modeling most practical problems and is capable of solving statics, vibration, buckling, and dynamic response problems of complex structures, including spinning ones. The aerodynamic module, AERO, enables computation of unsteady aerodynamic forces for both subsonic and supersonic flow for subsequent flutter and divergence analysis of the structure. The associated aeroservoelastic analysis module, ASE, effects aero-structural-control stability analysis yielding frequency responses as well as damping characteristics of the structure. The program is written in standard FORTRAN to run on a wide variety of computers. Extensive graphics, preprocessing, and postprocessing routines are also available pertaining to a number of terminals.

XAP, a program for deconvolution and analysis of complex X-ray spectra

USGS Publications Warehouse

Quick, James E.; Haleby, Abdul Malik

1989-01-01

The X-ray analysis program (XAP) is a spectral-deconvolution program written in BASIC and specifically designed to analyze complex spectra produced by energy-dispersive X-ray analytical systems (EDS). XAP compensates for spectrometer drift, utilizes digital filtering to remove background from spectra, and solves for element abundances by least-squares, multiple-regression analysis. Rather than base analyses on only a few channels, broad spectral regions of a sample are reconstructed from standard reference spectra. The effects of this approach are (1) elimination of tedious spectrometer adjustments, (2) removal of background independent of sample composition, and (3) automatic correction for peak overlaps. Although the program was written specifically to operate a KEVEX 7000 X-ray fluorescence analytical system, it could be adapted (with minor modifications) to analyze spectra produced by scanning electron microscopes, electron microprobes, and probes, and X-ray defractometer patterns obtained from whole-rock powders.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Russell, J.S.

Several factors in the development of the East Wilmington oil field by THUMS Long Beach Co. are described. These include: critical path scheduling, complex stratigraphy, reservoir engineering, drilling program, production methods, pressure maintenance, crude oil processing, automation, transportation facilities, service lines, and electrical facilities. The complexity and closely scheduled operational events interwoven in the THUMS project demands a method for the carefully planned sequence of jobs to be done, beginning with island construction up through routine production and to the LACT system. These demanding requirements necessitated the use of a critical path scheduling program. It was decided to use themore » program evaluation technique. This technique is used to assign responsibilities for individual assignments to time assignments, and to keep the overall program on schedule. The stratigraphy of East Wilmington complicates all engineering functions associated with recovery methods and reservoir evaluation. At least 5 major faults are anticipated.« less

Configuration Management at NASA

NASA Technical Reports Server (NTRS)

Doreswamy, Rajiv

2013-01-01

NASA programs are characterized by complexity, harsh environments and the fact that we usually have one chance to get it right. Programs last decades and need to accept new hardware and technology as it is developed. We have multiple suppliers and international partners Our challenges are many, our costs are high and our failures are highly visible. CM systems need to be scalable, adaptable to new technology and span the life cycle of the program (30+ years). Multiple Systems, Contractors and Countries added major levels of complexity to the ISS program and CM/DM and Requirements management systems center dot CM Systems need to be designed for long design life center dot Space Station Design started in 1984 center dot Assembly Complete in 2012 center dot Systems were developed on a task basis without an overall system perspective center dot Technology moves faster than a large project office, try to make sure you have a system that can adapt

Langley Aerothermodynamic Facilities Complex: Enhancements and Testing Capabilities

NASA Technical Reports Server (NTRS)

Micol, J. R.

1998-01-01

Description, capabilities, recent upgrades, and utilization of the NASA Langley Research Center (LaRC) Aerothermodynamic Facilities Complex (AFC) are presented. The AFC consists of five hypersonic, blow-down-to-vacuum wind tunnels that collectively provide a range of Mach number from 6 to 20, unit Reynolds number from 0.04 to 22 million per foot and, most importantly for blunt configurations, normal shock density ratio from 4 to 12. These wide ranges of hypersonic simulation parameters are due, in part, to the use of three different test gases (air, helium, and tetrafluoromethane), thereby making several of the facilities unique. The Complex represents nearly three-fourths of the conventional (as opposed to impulse)-type hypersonic wind tunnels operational in this country. AFC facilities are used to assess and optimize the hypersonic aerodynamic performance and aeroheating characteristics of aerospace vehicle concepts and to provide benchmark aerodynamic/aeroheating data fr generating the flight aerodynamic databook and final design of the thermal protection system (TPS) (e.g., establishment of flight limitations not to exceed TPS design limits). Modifications and enhancements of AFC hardware components and instrumentation have been pursued to increase capability, reliability, and productivity in support of programmatic goals. Examples illustrating facility utilization in recent years to generate essentially all of the experimental hypersonic aerodynamic and aeroheating information for high-priority, fast-paced Agency programs are presented. These programs include Phase I of the Reusable Launch Vehicle (RLV) Advanced Technology Demonstrator, X-33 program, PHase II of the X-33 program, X-34 program, the Hyper-X program ( a Mach 5,7, and 10 airbreathing propulsion flight experiment), and the X-38 program (Experimental Crew Return Vehicle, X-CRV). Current upgrades/enchancements and future plans for the AFC are discussed.

Genetic programming approach to evaluate complexity of texture images

NASA Astrophysics Data System (ADS)

Ciocca, Gianluigi; Corchs, Silvia; Gasparini, Francesca

2016-11-01

We adopt genetic programming (GP) to define a measure that can predict complexity perception of texture images. We perform psychophysical experiments on three different datasets to collect data on the perceived complexity. The subjective data are used for training, validation, and test of the proposed measure. These data are also used to evaluate several possible candidate measures of texture complexity related to both low level and high level image features. We select four of them (namely roughness, number of regions, chroma variance, and memorability) to be combined in a GP framework. This approach allows a nonlinear combination of the measures and could give hints on how the related image features interact in complexity perception. The proposed complexity measure M exhibits Pearson correlation coefficients of 0.890 on the training set, 0.728 on the validation set, and 0.724 on the test set. M outperforms each of all the single measures considered. From the statistical analysis of different GP candidate solutions, we found that the roughness measure evaluated on the gray level image is the most dominant one, followed by the memorability, the number of regions, and finally the chroma variance.

[The analysis of complex interventions in public health: the case of the prevention of sexually transmitted infections and blood-borne infections in Montreal].

PubMed

Bilodeau, Angèle; Beauchemin, Jean; Bourque, Denis; Galarneau, Marilène

2013-02-11

Based on a theory of intervention as a complex action system, analyze collaboration among partners in Montréal's sexually transmitted and blood-borne infections (STBBI) prevention program to identify main operations problems and possible scenarios for change to achieve better outcomes. A descriptive study was conducted using three data sources - public policies and programs, system management documents, and interviews with three types of partners. The results were validated with stakeholders. Five main operations problems affecting the capacity of the system to provide expected services were identified, as well as strategies the partners use to address these. Two scenarios for system change to increase its effectiveness in achieving program goals are discussed.

Scientific Programming Using Java: A Remote Sensing Example

NASA Technical Reports Server (NTRS)

Prados, Don; Mohamed, Mohamed A.; Johnson, Michael; Cao, Changyong; Gasser, Jerry

1999-01-01

This paper presents results of a project to port remote sensing code from the C programming language to Java. The advantages and disadvantages of using Java versus C as a scientific programming language in remote sensing applications are discussed. Remote sensing applications deal with voluminous data that require effective memory management, such as buffering operations, when processed. Some of these applications also implement complex computational algorithms, such as Fast Fourier Transformation analysis, that are very performance intensive. Factors considered include performance, precision, complexity, rapidity of development, ease of code reuse, ease of maintenance, memory management, and platform independence. Performance of radiometric calibration code written in Java for the graphical user interface and of using C for the domain model are also presented.

A web interface for easy flexible protein-protein docking with ATTRACT.

PubMed

de Vries, Sjoerd J; Schindler, Christina E M; Chauvot de Beauchêne, Isaure; Zacharias, Martin

2015-02-03

Protein-protein docking programs can give valuable insights into the structure of protein complexes in the absence of an experimental complex structure. Web interfaces can facilitate the use of docking programs by structural biologists. Here, we present an easy web interface for protein-protein docking with the ATTRACT program. While aimed at nonexpert users, the web interface still covers a considerable range of docking applications. The web interface supports systematic rigid-body protein docking with the ATTRACT coarse-grained force field, as well as various kinds of protein flexibility. The execution of a docking protocol takes up to a few hours on a standard desktop computer. Copyright © 2015 Biophysical Society. Published by Elsevier Inc. All rights reserved.

Systems Engineering Design Via Experimental Operation Research: Complex Organizational Metric for Programmatic Risk Environments (COMPRE)

NASA Technical Reports Server (NTRS)

Mog, Robert A.

1999-01-01

Unique and innovative graph theory, neural network, organizational modeling, and genetic algorithms are applied to the design and evolution of programmatic and organizational architectures. Graph theory representations of programs and organizations increase modeling capabilities and flexibility, while illuminating preferable programmatic/organizational design features. Treating programs and organizations as neural networks results in better system synthesis, and more robust data modeling. Organizational modeling using covariance structures enhances the determination of organizational risk factors. Genetic algorithms improve programmatic evolution characteristics, while shedding light on rulebase requirements for achieving specified technological readiness levels, given budget and schedule resources. This program of research improves the robustness and verifiability of systems synthesis tools, including the Complex Organizational Metric for Programmatic Risk Environments (COMPRE).

After the Visit: An Overview of Government and Community Programs Supporting Children with Medical Complexity.

PubMed

Olson, Kaitlyn B

2017-05-04

The optimal care of children with medical complexity (CMC) requires involvement from a network of professionals that includes physicians, nurses, ancillary service providers, and educators. Pediatric health care providers typically have early and frequent contact with the families of CMC. Therefore, they are in a unique position to connect families to developmental, educational, and psychosocial supports. This article reviews important government and community programs that support CMC living in the United States. It outlines the educational rights of children with disabilities and offers practical tips for collaborating with Early Intervention and the public school system. The article also provides an overview of financial assistance programs, respite care services, and support groups that are beneficial to CMC and their families.

A Matched Project Evaluation of Modern Programming Practices. Volume II. Scientific Report on the ASTROS Plan.

DTIC Science & Technology

1980-02-01

formula for predictinq the number of errors during system testing. The equation he presents is B V/ ECRIT where B is the number of 19 ’R , errors...expected, V is the volume, and ECRIT is "the mean number of elementary discriminations between potential errors in programming" (p. 85). E CRIT can also...prediction of delivered bugs is: "V VX 2 B = V/ ECRIT -3- 13,824 2.3 McCabe’s Complexity Metric Thomas McCabe (1976) defined complexity in relation to

An implementation of the distributed programming structural synthesis system (PROSSS)

NASA Technical Reports Server (NTRS)

Rogers, J. L., Jr.

1981-01-01

A method is described for implementing a flexible software system that combines large, complex programs with small, user-supplied, problem-dependent programs and that distributes their execution between a mainframe and a minicomputer. The Programming Structural Synthesis System (PROSSS) was the specific software system considered. The results of such distributed implementation are flexibility of the optimization procedure organization and versatility of the formulation of constraints and design variables.

The Lewis Chemical Equilibrium Program with parametric study capability

NASA Technical Reports Server (NTRS)

Sevigny, R.

1981-01-01

The program was developed to determine chemical equilibrium in complex systems. Using a free energy minimization technique, the program permits calculations such as: chemical equilibrium for assigned thermodynamic states; theoretical rocket performance for both equilibrium and frozen compositions during expansion; incident and reflected shock properties; and Chapman-Jouget detonation properties. It is shown that the same program can handle solid coal in an entrained flow coal gasification problem.

Computer Program for Calculation of Complex Chemical Equilibrium Compositions and Applications II. Users Manual and Program Description. 2; Users Manual and Program Description

NASA Technical Reports Server (NTRS)

McBride, Bonnie J.; Gordon, Sanford

1996-01-01

This users manual is the second part of a two-part report describing the NASA Lewis CEA (Chemical Equilibrium with Applications) program. The program obtains chemical equilibrium compositions of complex mixtures with applications to several types of problems. The topics presented in this manual are: (1) details for preparing input data sets; (2) a description of output tables for various types of problems; (3) the overall modular organization of the program with information on how to make modifications; (4) a description of the function of each subroutine; (5) error messages and their significance; and (6) a number of examples that illustrate various types of problems handled by CEA and that cover many of the options available in both input and output. Seven appendixes give information on the thermodynamic and thermal transport data used in CEA; some information on common variables used in or generated by the equilibrium module; and output tables for 14 example problems. The CEA program was written in ANSI standard FORTRAN 77. CEA should work on any system with sufficient storage. There are about 6300 lines in the source code, which uses about 225 kilobytes of memory. The compiled program takes about 975 kilobytes.

A Comparison of Four Software Programs for Implementing Decision Analytic Cost-Effectiveness Models.

PubMed

Hollman, Chase; Paulden, Mike; Pechlivanoglou, Petros; McCabe, Christopher

2017-08-01

The volume and technical complexity of both academic and commercial research using decision analytic modelling has increased rapidly over the last two decades. The range of software programs used for their implementation has also increased, but it remains true that a small number of programs account for the vast majority of cost-effectiveness modelling work. We report a comparison of four software programs: TreeAge Pro, Microsoft Excel, R and MATLAB. Our focus is on software commonly used for building Markov models and decision trees to conduct cohort simulations, given their predominance in the published literature around cost-effectiveness modelling. Our comparison uses three qualitative criteria as proposed by Eddy et al.: "transparency and validation", "learning curve" and "capability". In addition, we introduce the quantitative criterion of processing speed. We also consider the cost of each program to academic users and commercial users. We rank the programs based on each of these criteria. We find that, whilst Microsoft Excel and TreeAge Pro are good programs for educational purposes and for producing the types of analyses typically required by health technology assessment agencies, the efficiency and transparency advantages of programming languages such as MATLAB and R become increasingly valuable when more complex analyses are required.

Program logic: a framework for health program design and evaluation - the Pap nurse in general practice program.

PubMed

Hallinan, Christine M

2010-01-01

In this paper, program logic will be used to 'map out' the planning, development and evaluation of the general practice Pap nurse program in the Australian general practice arena. The incorporation of program logic into the evaluative process supports a greater appreciation of the theoretical assumptions and external influences that underpin general practice Pap nurse activity. The creation of a program logic model is a conscious strategy that results an explicit understanding of the challenges ahead, the resources available and time frames for outcomes. Program logic also enables a recognition that all players in the general practice arena need to be acknowledged by policy makers, bureaucrats and program designers when addressing through policy, issues relating to equity and accessibility of health initiatives. Logic modelling allows decision makers to consider the complexities of causal associations when developing health care proposals and programs. It enables the Pap nurse in general practice program to be represented diagrammatically by linking outcomes (short, medium and long term) with both the program activities and program assumptions. The research methodology used in the evaluation of the Pap nurse in general practice program includes a descriptive study design and the incorporation of program logic, with a retrospective analysis of Australian data from 2001 to 2009. For the purposes of gaining both empirical and contextual data for this paper, a data set analysis and literature review was performed. The application of program logic as an evaluative tool for analysis of the Pap PN incentive program facilitates a greater understanding of complex general practice activity triggers, and also allows this greater understanding to be incorporated into policy to facilitate Pap PN activity, increase general practice cervical smear and ultimately decrease burden of disease.

Causal inferences on the effectiveness of complex social programs: Navigating assumptions, sources of complexity and evaluation design challenges.

PubMed

Chatterji, Madhabi

2016-12-01

This paper explores avenues for navigating evaluation design challenges posed by complex social programs (CSPs) and their environments when conducting studies that call for generalizable, causal inferences on the intervention's effectiveness. A definition is provided of a CSP drawing on examples from different fields, and an evaluation case is analyzed in depth to derive seven (7) major sources of complexity that typify CSPs, threatening assumptions of textbook-recommended experimental designs for performing impact evaluations. Theoretically-supported, alternative methodological strategies are discussed to navigate assumptions and counter the design challenges posed by the complex configurations and ecology of CSPs. Specific recommendations include: sequential refinement of the evaluation design through systems thinking, systems-informed logic modeling; and use of extended term, mixed methods (ETMM) approaches with exploratory and confirmatory phases of the evaluation. In the proposed approach, logic models are refined through direct induction and interactions with stakeholders. To better guide assumption evaluation, question-framing, and selection of appropriate methodological strategies, a multiphase evaluation design is recommended. Copyright © 2016 Elsevier Ltd. All rights reserved.

Electrostatic design of protein-protein association rates.

PubMed

Schreiber, Gideon; Shaul, Yossi; Gottschalk, Kay E

2006-01-01

De novo design and redesign of proteins and protein complexes have made promising progress in recent years. Here, we give an overview of how to use available computer-based tools to design proteins to bind faster and tighter to their protein-complex partner by electrostatic optimization between the two proteins. Electrostatic optimization is possible because of the simple relation between the Debye-Huckel energy of interaction between a pair of proteins and their rate of association. This can be used for rapid, structure-based calculations of the electrostatic attraction between the two proteins in the complex. Using these principles, we developed two computer programs that predict the change in k(on), and as such the affinity, on introducing charged mutations. The two programs have a web interface that is available at www.weizmann.ac.il/home/bcges/PARE.html and http://bip.weizmann.ac.il/hypare. When mutations leading to charge optimization are introduced outside the physical binding site, the rate of dissociation is unchanged and therefore the change in k(on) parallels that of the affinity. This design method was evaluated on a number of different protein complexes resulting in binding rates and affinities of hundreds of fold faster and tighter compared to wild type. In this chapter, we demonstrate the procedure and go step by step over the methodology of using these programs for protein-association design. Finally, the way to easily implement the principle of electrostatic design for any protein complex of choice is shown.

1991 Annual report on scientific programs: A broad research program on the sciences of complexity

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1991-01-01

1991 was continued rapid growth for the Santa Fe Institute (SFI) as it broadened its interdisciplinary research into the organization, evolution and operation of complex systems and sought deeply the principles underlying their dynamic behavior. Research on complex systems--the focus of work at SFI--involves an extraordinary range of topics normally studied in seemingly disparate fields. Natural systems displaying complex behavior range upwards from proteins and DNA through cells and evolutionary systems to human societies. Research models exhibiting complexity include nonlinear equations, spin glasses, cellular automata, genetic algorithms, classifier systems, and an array of other computational models. Some of the majormore » questions facing complex systems researchers are: (1) explaining how complexity arises from the nonlinear interaction of simples components, (2) describing the mechanisms underlying high-level aggregate behavior of complex systems (such as the overt behavior of an organism, the flow of energy in an ecology, the GNP of an economy), and (3) creating a theoretical framework to enable predictions about the likely behavior of such systems in various conditions. The importance of understanding such systems in enormous: many of the most serious challenges facing humanity--e.g., environmental sustainability, economic stability, the control of disease--as well as many of the hardest scientific questions--e.g., protein folding, the distinction between self and non-self in the immune system, the nature of intelligence, the origin of life--require deep understanding of complex systems.« less

1991 Annual report on scientific programs: A broad research program on the sciences of complexity

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1991-12-31

1991 was continued rapid growth for the Santa Fe Institute (SFI) as it broadened its interdisciplinary research into the organization, evolution and operation of complex systems and sought deeply the principles underlying their dynamic behavior. Research on complex systems--the focus of work at SFI--involves an extraordinary range of topics normally studied in seemingly disparate fields. Natural systems displaying complex behavior range upwards from proteins and DNA through cells and evolutionary systems to human societies. Research models exhibiting complexity include nonlinear equations, spin glasses, cellular automata, genetic algorithms, classifier systems, and an array of other computational models. Some of the majormore » questions facing complex systems researchers are: (1) explaining how complexity arises from the nonlinear interaction of simples components, (2) describing the mechanisms underlying high-level aggregate behavior of complex systems (such as the overt behavior of an organism, the flow of energy in an ecology, the GNP of an economy), and (3) creating a theoretical framework to enable predictions about the likely behavior of such systems in various conditions. The importance of understanding such systems in enormous: many of the most serious challenges facing humanity--e.g., environmental sustainability, economic stability, the control of disease--as well as many of the hardest scientific questions--e.g., protein folding, the distinction between self and non-self in the immune system, the nature of intelligence, the origin of life--require deep understanding of complex systems.« less

A Study of College Students' Construct of Parameter Passing Implications for Instruction.

ERIC Educational Resources Information Center

Madison, Sandra Kay

Parameter passing is the mechanism by which various program modules share information in a complex program; this paper was a study of novice programmers' understanding of the parameter construct. The bulk of the data was collected from interviews with eight college students enrolled in a state university introductory computer programming course.…

Analysis of Learning Behavior in a Flipped Programing Classroom Adopting Problem-Solving Strategies

ERIC Educational Resources Information Center

Chiang, Tosti Hsu-Cheng

2017-01-01

Programing is difficult for beginners because they need to learn the new language of computers. Developing software, especially complex software, is bound to result in problems, frustration, and the need to think in new ways. Identifying the learning behavior behind programing by way of empirical studies can help beginners learn more easily. In…

Tackling the Law and Raising the Issues: Summer Program Prepares Students.

ERIC Educational Resources Information Center

Bowannie, Mary

2003-01-01

An intensive 8-week summer program in New Mexico prepares American Indian and Alaska Native students to succeed in law school, focusing on law research, analysis, and writing. Two program graduates who went on to complete law school discuss the complexities of federal Indian law and the Native lawyers' responsibility to their communities--an…

Recognizing and Managing Complexity: Teaching Advanced Programming Concepts and Techniques Using the Zebra Puzzle

ERIC Educational Resources Information Center

Crabtree, John; Zhang, Xihui

2015-01-01

Teaching advanced programming can be a challenge, especially when the students are pursuing different majors with diverse analytical and problem-solving capabilities. The purpose of this paper is to explore the efficacy of using a particular problem as a vehicle for imparting a broad set of programming concepts and problem-solving techniques. We…

Design and Development of an Interactive Multimedia Simulation for Augmenting the Teaching and Learning of Programming Concepts

ERIC Educational Resources Information Center

Baloyi, Leonah L.; Ojo, Sunday O.; Van Wyk, Etienne A.

2017-01-01

Teaching and learning programming has presented many challenges in institutions of higher learning worldwide. Teaching and learning programming require cognitive reasoning, mainly due to the fundamental reality that the underlying concepts are complex and abstract. As a result, many institutions of higher learning are faced with low success rates…

Planning the Fire Program for the Third Millennium

Treesearch

Richard A. Chase

1987-01-01

The fire program planner faces an increasingly complex task as diverse--and often contradictory--messages about objectives and constraints are received from political, administrative, budgetary, and social processes. Our principal challenge as we move into the 21st century is not one of looking for flashier technology to include in the planned fire program. Rather, we...

Using the Self-Select Paradigm to Delineate the Nature of Speech Motor Programming

ERIC Educational Resources Information Center

Wright, David L.; Robin, Don A.; Rhee, Jooyhun; Vaculin, Amber; Jacks, Adam; Guenther, Frank H.; Fox, Peter T.

2009-01-01

Purpose: The authors examined the involvement of 2 speech motor programming processes identified by S. T. Klapp (1995, 2003) during the articulation of utterances differing in syllable and sequence complexity. According to S. T. Klapp, 1 process, INT, resolves the demands of the programmed unit, whereas a second process, SEQ, oversees the serial…

ARI Basic Research Program FY 1999-2000

DTIC Science & Technology

1999-06-01

visual cues, reinforcement, and instruction concerning abstract , general rules. In our future research, we plan to examine the learning of novel...Watch, • Graduate student apprenticeship program - Consortium Research Fellows Program- with the Consortium of Metropolitan Washington Universities...do learn complex rules involving different levels of abstraction when given sufficient specific examples but that they also benefit from explicit

Camp Verde Adult Reading Program. Final Performance Report.

ERIC Educational Resources Information Center

Maynard, David A.

This document begins with a four-page performance report describing how the Camp Verde Adult Reading Program site was relocated to the Community Center Complex, and the Town Council contracted directly with the Friends of the Camp Verde Library to provide for the requirements of the program. The U.S. Department of Education grant allowed the…

The Complexities of a Third-Space Partnership in an Urban Teacher Residency

ERIC Educational Resources Information Center

Beck, Jori S.

2016-01-01

Urban teacher residency (UTR) programs have been widely endorsed (National Education Association, 2014; Thorpe, 2014), yet the body of literature on these programs has not definitively identified the benefits of UTRs over and above traditional teacher education programs--if any exist. The current study explored how faculty and staff working in one…

Introductory Computer Programming Course Teaching Improvement Using Immersion Language, Extreme Programming, and Education Theories

ERIC Educational Resources Information Center

Velez-Rubio, Miguel

2013-01-01

Teaching computer programming to freshmen students in Computer Sciences and other Information Technology areas has been identified as a complex activity. Different approaches have been studied looking for the best one that could help to improve this teaching process. A proposed approach was implemented which is based in the language immersion…

Interdisciplinarity, Qualitative Research, and the Complex Phenomenon: Toward an Integrative Approach to Intercultural Research

ERIC Educational Resources Information Center

Ryan, Phillip; Kurtz, Jill Sornsen; Carter, Deanne; Pester, Danielle

2014-01-01

This article is a collaboration by the lead faculty member in a Masters program in Intercultural Studies and students who completed the program under his aegis. This article presents the program's approach to its research course sequence, an approach involving the integration of interdisciplinary and qualitative research. The authors first provide…

The Application of Traditional Martial Arts Practice and Theory to the Treatment of Violent Adolescents.

ERIC Educational Resources Information Center

Twemlow, Stuart W.; Sacco, Frank C.

1998-01-01

Reviews treatment programs, the complex problems posed by youth gangs, and the use of martial arts in the treatment of violence and proposes a program for violent adolescents. The program philosophy is committed to respect and self-control; emphasis is on leadership and community service. Provides clinical examples. (Author/EMK)

Mission Analysis Program for Solar Electric Propulsion (MAPSEP). Volume 3: Program manual for earth orbital MAPSEP

NASA Technical Reports Server (NTRS)

1975-01-01

A revised user's manual for the computer program MAPSEP is presented. Major changes from the interplanetary version of MAPSEP are summarized. The changes are intended to provide a basic capability to analyze anticipated solar electric missions, and a foundation for future more complex, modifications. For Vol. III, N75-16589.

Systems approach provides management control of complex programs

NASA Technical Reports Server (NTRS)

Dudek, E. F., Jr.; Mc Carthy, J. F., Jr.

1970-01-01

Integrated program management process provides management visual assistance through three interrelated charts - system model that identifies each function to be performed, matrix that identifies personnel responsibilities for these functions, process chart that breaks down the functions into discrete tasks.

Internet-Mediated Learning in Public Affairs Programs: Issues and Implications.

ERIC Educational Resources Information Center

Rahm, Dianne; Reed, B. J.; Rydl, Teri L.

1999-01-01

An overview of Internet-mediated learning in public affairs programs identifies issues for faculty, students, and administrators, including intellectual property rights, instructional issues, learning approaches, student expectations, logistics and support, complexity of coordination, and organizational control. (DB)

Can a Reaction's Environment Program its Outcome, and Does it Matter?

NASA Astrophysics Data System (ADS)

Surman, A. J.; Rodriguez-Garcia, M.; Abul-Haija, Y.; Cooper, G. J. T.; Donkers, K.; Planchat i Barbarà, J. M.; Kube, J.; Mullin, M.; Hezwani, M.; Cronin, L.

2017-07-01

Where most eschew reactions producing complex mixtures (‘tar') and prefer to plan ‘clean' syntheses, we embrace complexity. We show that environments can steer ‘messy' reactions, and ask if this can yield significant difference in structure and function.

Program for the Division of Chemical Education: Chicago, March 25 29, 2007

NASA Astrophysics Data System (ADS)

Middlecamp, Catherine H.; Bodner, George M.; Jones, Wayne E., Jr.

2007-03-01

Program for the Division of Chemical Education March 2007 meeting in Chicago. All CHED technical sessions including the High School Program will be held in the McCormick Place Convention Complex North, 2301 South Lake Shore Drive. Exceptions are the Undergraduate Program (in the Westin Hotel Michigan Avenue), the Undergraduate Research Poster Sessions (in the Sheraton Chicago Hotel), and any evening programs. Unless otherwise noted, morning sessions begin at 8:30 a.m., afternoon sessions at 1:30 p.m.

A Comparative Analysis of the Resources Required for Test and Evaluation on Army-Led Weapon System Programs, Based Upon Program Size and Acquisition Management Complexity

DTIC Science & Technology

2007-12-01

Program Manager PMO Program Manager Office POM Program Objective Memorandum PPE Personal Protective Equipment PPT Production Prove...test • Technical feasibility test • Engineering development test • Production prove-out test ( PPT ) • Software qualification test 22 • Live fire...improvement BIDS (P3I) system is equipped with a detection suite to include high volume samplers, a fluorescent particle counter/sizer, a flow

Self assembly of rectangular shapes on concentration programming and probabilistic tile assembly models.

PubMed

Kundeti, Vamsi; Rajasekaran, Sanguthevar

2012-06-01

Efficient tile sets for self assembling rectilinear shapes is of critical importance in algorithmic self assembly. A lower bound on the tile complexity of any deterministic self assembly system for an n × n square is [Formula: see text] (inferred from the Kolmogrov complexity). Deterministic self assembly systems with an optimal tile complexity have been designed for squares and related shapes in the past. However designing [Formula: see text] unique tiles specific to a shape is still an intensive task in the laboratory. On the other hand copies of a tile can be made rapidly using PCR (polymerase chain reaction) experiments. This led to the study of self assembly on tile concentration programming models. We present two major results in this paper on the concentration programming model. First we show how to self assemble rectangles with a fixed aspect ratio ( α:β ), with high probability, using Θ( α + β ) tiles. This result is much stronger than the existing results by Kao et al. (Randomized self-assembly for approximate shapes, LNCS, vol 5125. Springer, Heidelberg, 2008) and Doty (Randomized self-assembly for exact shapes. In: proceedings of the 50th annual IEEE symposium on foundations of computer science (FOCS), IEEE, Atlanta. pp 85-94, 2009)-which can only self assembly squares and rely on tiles which perform binary arithmetic. On the other hand, our result is based on a technique called staircase sampling . This technique eliminates the need for sub-tiles which perform binary arithmetic, reduces the constant in the asymptotic bound, and eliminates the need for approximate frames (Kao et al. Randomized self-assembly for approximate shapes, LNCS, vol 5125. Springer, Heidelberg, 2008). Our second result applies staircase sampling on the equimolar concentration programming model (The tile complexity of linear assemblies. In: proceedings of the 36th international colloquium automata, languages and programming: Part I on ICALP '09, Springer-Verlag, pp 235-253, 2009), to self assemble rectangles (of fixed aspect ratio) with high probability. The tile complexity of our algorithm is Θ(log( n )) and is optimal on the probabilistic tile assembly model (PTAM)- n being an upper bound on the dimensions of a rectangle.

Is the integration of nutritional care in the different assistance levels possible? The Catalan experience. Clinical perspective

PubMed

Burgos Peláez, Rosa; Joaquin Ortiz, Clara; Vaqué Crusellas, Cristina

2017-05-08

Disease-related malnutrition is highly prevalent in pathologies commonly integrating care complexity. Healthcare models for complexity must include malnutrition detection and approaches, since it is a key factor which has great impact on the patient’s evolution and the consumption of healthcare resources. Malnourished patients present higher hospitalization, complication and mortality rates, higher demand of post-discharge social resources and higher hospital readmission frequency. Detecting malnutrition is necessary to implement a nutritional care program which might be used in any assistance level. The integration of health and social care and the development of information tools which are shared by the different assistance agents has allowed the development of a program for the management of disease-related malnutrition in patients with clinical complexity in Catalonia.

Non-covalent synthesis of supermicelles with complex architectures using spatially confined hydrogen-bonding interactions

PubMed Central

Li, Xiaoyu; Gao, Yang; Boott, Charlotte E.; Winnik, Mitchell A.; Manners, Ian

2015-01-01

Nature uses orthogonal interactions over different length scales to construct structures with hierarchical levels of order and provides an important source of inspiration for the creation of synthetic functional materials. Here, we report the programmed assembly of monodisperse cylindrical block comicelle building blocks with crystalline cores to create supermicelles using spatially confined hydrogen-bonding interactions. We also demonstrate that it is possible to further program the self-assembly of these synthetic building blocks into structures of increased complexity by combining hydrogen-bonding interactions with segment solvophobicity. The overall approach offers an efficient, non-covalent synthesis method for the solution-phase fabrication of a range of complex and potentially functional supermicelle architectures in which the crystallization, hydrogen-bonding and solvophobic interactions are combined in an orthogonal manner. PMID:26337527

Some thoughts on the management of large, complex international space ventures

NASA Technical Reports Server (NTRS)

Lee, T. J.; Kutzer, Ants; Schneider, W. C.

1992-01-01

Management issues relevant to the development and deployment of large international space ventures are discussed with particular attention given to previous experience. Management approaches utilized in the past are labeled as either simple or complex, and signs of efficient management are examined. Simple approaches include those in which experiments and subsystems are developed for integration into spacecraft, and the Apollo-Soyuz Test Project is given as an example of a simple multinational approach. Complex approaches include those for ESA's Spacelab Project and the Space Station Freedom in which functional interfaces cross agency and political boundaries. It is concluded that individual elements of space programs should be managed by individual participating agencies, and overall configuration control is coordinated by level with a program director acting to manage overall objectives and project interfaces.

KSC-2012-2888

NASA Image and Video Library

2012-05-21

CAPE CANAVERAL, Fla. – At the NASA Railroad yard at Kennedy Space Center in Florida, helium tank cars are lifted from their trucks onto flat cars in preparation for a journey to the Florida East Coast Railway interchange in Titusville, Fla., where the train’s tank cars will be transferred for delivery to the SpaceX engine test complex outside McGregor, Texas. The railroad cars were needed in support of the Space Shuttle Program but currently are not in use by NASA following the completion of the program in 2011. Originally, the tankers belonged to the U.S. Bureau of Mines. At the peak of the shuttle program, there were approximately 30 cars in the fleet. About half the cars were returned to the bureau as launch activity diminished. Five tank cars are being loaned to SpaceX and repurposed to support their engine tests in Texas. Eight cars previously were shipped to California on loan to support the SpaceX Falcon 9 rocket launches from Space Launch Complex-4 on Vandenberg Air Force Base. SpaceX already has three helium tank cars previously used for the shuttle program at Space Launch Complex-40 on Cape Canaveral Air Force Station in Florida. For more information, visit http://www.nasa.gov/spacex. Photo credit: NASA/Jim Grossmann

KSC-2012-3057

NASA Image and Video Library

2012-05-23

CAPE CANAVERAL, Fla. – The drawbridge span of the NASA Railroad’s Jay Jay Railroad Bridge over the Indian River north of Launch Complex 39 at NASA’s Kennedy Space Center in Florida is reopened following the passage of a NASA Railroad train. The permanent configuration of the bridge is open the span is lowered only for a train to cross. The railroad cars were needed in support of the Space Shuttle Program but currently are not in use by NASA following the completion of the program in 2011. Originally, the tankers belonged to the U.S. Bureau of Mines. At the peak of the shuttle program, there were approximately 30 cars in the fleet. About half the cars were returned to the bureau as launch activity diminished. Five tank cars are being loaned to SpaceX and repurposed to support their engine tests in Texas. Eight cars previously were shipped to California on loan to support the SpaceX Falcon 9 rocket launches from Space Launch Complex-4 on Vandenberg Air Force Base. SpaceX already has three helium tank cars previously used for the shuttle program at Space Launch Complex-40 on Cape Canaveral Air Force Station in Florida. For more information, visit http://www.nasa.gov/spacex. Photo credit: NASA/Jim Grossmann

KSC-2012-2890

NASA Image and Video Library

2012-05-21

CAPE CANAVERAL, Fla. – At the NASA Railroad yard at Kennedy Space Center in Florida, helium tank cars have been removed from their trucks and loaded onto flat cars in preparation for a journey to the Florida East Coast Railway interchange in Titusville, Fla., where the train’s tank cars will be transferred for delivery to the SpaceX engine test complex outside McGregor, Texas. The railroad cars were needed in support of the Space Shuttle Program but currently are not in use by NASA following the completion of the program in 2011. Originally, the tankers belonged to the U.S. Bureau of Mines. At the peak of the shuttle program, there were approximately 30 cars in the fleet. About half the cars were returned to the bureau as launch activity diminished. Five tank cars are being loaned to SpaceX and repurposed to support their engine tests in Texas. Eight cars previously were shipped to California on loan to support the SpaceX Falcon 9 rocket launches from Space Launch Complex-4 on Vandenberg Air Force Base. SpaceX already has three helium tank cars previously used for the shuttle program at Space Launch Complex-40 on Cape Canaveral Air Force Station in Florida. For more information, visit http://www.nasa.gov/spacex. Photo credit: NASA/Jim Grossmann

The Dryden Flight Research Center at Edwards Air Force Base is NASA's premier center for atmospheric flight research to validate high-risk aerospace technology.

NASA Image and Video Library

2001-07-25

Since the 1940s the Dryden Flight Research Center, Edwards, California, has developed a unique and highly specialized capability for conducting flight research programs. The organization, made up of pilots, scientists, engineers, technicians, and mechanics, has been and will continue to be leaders in the field of advanced aeronautics. Located on the northwest "shore" of Rogers Dry Lake, the complex was built around the original administrative-hangar building constructed in 1954. Since then many additional support and operational facilities have been built including a number of unique test facilities such as the Thermalstructures Research Facility, Flow Visualization Facility, and the Integrated Test Facility. One of the most prominent structures is the space shuttle program's Mate-Demate Device and hangar in Area A to the north of the main complex. On the lakebed surface is a Compass Rose that gives pilots an instant compass heading. The Dryden complex originated at Edwards Air Force Base in support of the X-1 supersonic flight program. As other high-speed aircraft entered research programs, the facility became permanent and grew from a staff of five engineers in 1947 to a population in 2006 of nearly 1100 full-time government and contractor employees.

NASA's Dryden Flight Research Center is situated immediately adjacent to the compass rose on the bed of Rogers Dry Lake at Edwards Air Force Base, Calif.

NASA Image and Video Library

2001-07-25

Since the 1940s the Dryden Flight Research Center, Edwards, California, has developed a unique and highly specialized capability for conducting flight research programs. The organization, made up of pilots, scientists, engineers, technicians, and mechanics, has been and will continue to be leaders in the field of advanced aeronautics. Located on the northwest "shore" of Rogers Dry Lake, the complex was built around the original administrative-hangar building constructed in 1954. Since then many additional support and operational facilities have been built including a number of unique test facilities such as the Thermalstructures Research Facility, Flow Visualization Facility, and the Integrated Test Facility. One of the most prominent structures is the space shuttle program's Mate-Demate Device and hangar in Area A to the north of the main complex. On the lakebed surface is a Compass Rose that gives pilots an instant compass heading. The Dryden complex originated at Edwards Air Force Base in support of the X-1 supersonic flight program. As other high-speed aircraft entered research programs, the facility became permanent and grew from a staff of five engineers in 1947 to a population in 2006 of nearly 1100 full-time government and contractor employees.

78 FR 18655 - Self-Regulatory Organizations; Chicago Board Options Exchange, Incorporated; Notice of Filing and...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-27

... from interested persons. \\1\\ 15 U.S.C. 78s(b)(1). \\2\\ 17 CFR 240.19b-4. I. Self-Regulatory Organization... simple, non-complex orders only. The Exchange now proposes to establish the Complex Order Router Subsidy... simple, non-complex orders under the ORS Program. The Participants would have to agree that they are not...

KSC-2012-3055

NASA Image and Video Library

2012-05-23

CAPE CANAVERAL, Fla. – A NASA Railroad train crosses the railroad’s Jay Jay Railroad Bridge north of Launch Complex 39 at NASA’s Kennedy Space Center in Florida. The train is on its way to the Florida East Coast Railway interchange in Titusville, Fla., where the train’s helium tank cars, a liquid oxygen tank car, and a liquid hydrogen dewar or tank car will be transferred for delivery to the SpaceX engine test complex outside McGregor, Texas. The helium tank cars are positioned in the front and rear of the train. The long, thin tank car in the middle was used for liquid hydrogen, followed by a much larger tank car used for liquid oxygen. The railroad cars were needed in support of the Space Shuttle Program but currently are not in use by NASA following the completion of the program in 2011. Originally, the tankers belonged to the U.S. Bureau of Mines. At the peak of the shuttle program, there were approximately 30 cars in the fleet. About half the cars were returned to the bureau as launch activity diminished. Five tank cars are being loaned to SpaceX and repurposed to support their engine tests in Texas. Eight cars previously were shipped to California on loan to support the SpaceX Falcon 9 rocket launches from Space Launch Complex-4 on Vandenberg Air Force Base. SpaceX already has three helium tank cars previously used for the shuttle program at Space Launch Complex-40 on Cape Canaveral Air Force Station in Florida. For more information, visit http://www.nasa.gov/spacex. Photo credit: NASA/Jim Grossmann

KSC-2012-3054

NASA Image and Video Library

2012-05-23

CAPE CANAVERAL, Fla. – A NASA Railroad train crosses the railroad’s Jay Jay Railroad Bridge north of Launch Complex 39 at NASA’s Kennedy Space Center in Florida. The train is on its way to the Florida East Coast Railway interchange in Titusville, Fla., where the train’s helium tank cars, a liquid oxygen tank car, and a liquid hydrogen dewar or tank car will be transferred for delivery to the SpaceX engine test complex outside McGregor, Texas. The helium tank cars are positioned in the front and rear of the train. The long, thin tank car in the middle was used for liquid hydrogen, followed by a much larger tank car used for liquid oxygen. The railroad cars were needed in support of the Space Shuttle Program but currently are not in use by NASA following the completion of the program in 2011. Originally, the tankers belonged to the U.S. Bureau of Mines. At the peak of the shuttle program, there were approximately 30 cars in the fleet. About half the cars were returned to the bureau as launch activity diminished. Five tank cars are being loaned to SpaceX and repurposed to support their engine tests in Texas. Eight cars previously were shipped to California on loan to support the SpaceX Falcon 9 rocket launches from Space Launch Complex-4 on Vandenberg Air Force Base. SpaceX already has three helium tank cars previously used for the shuttle program at Space Launch Complex-40 on Cape Canaveral Air Force Station in Florida. For more information, visit http://www.nasa.gov/spacex. Photo credit: NASA/Jim Grossmann

KSC-2012-3047

NASA Image and Video Library

2012-05-23

CAPE CANAVERAL, Fla. – Preparations are under way at the NASA Railroad’s Jay Jay Railroad Bridge north of Launch Complex 39 at NASA’s Kennedy Space Center in Florida for the passage of the NASA Railroad train on its way to the Florida East Coast Railway interchange in Titusville, Fla., where the train’s helium tank cars, a liquid oxygen tank car, and a liquid hydrogen dewar or tank car will be transferred for delivery to the SpaceX engine test complex outside McGregor, Texas. The permanent configuration of the drawbridge span is open, but the span will be lowered for a train to cross. The railroad cars were needed in support of the Space Shuttle Program but currently are not in use by NASA following the completion of the program in 2011. Originally, the tankers belonged to the U.S. Bureau of Mines. At the peak of the shuttle program, there were approximately 30 cars in the fleet. About half the cars were returned to the bureau as launch activity diminished. Five tank cars are being loaned to SpaceX and repurposed to support their engine tests in Texas. Eight cars previously were shipped to California on loan to support the SpaceX Falcon 9 rocket launches from Space Launch Complex-4 on Vandenberg Air Force Base. SpaceX already has three helium tank cars previously used for the shuttle program at Space Launch Complex-40 on Cape Canaveral Air Force Station in Florida. For more information, visit http://www.nasa.gov/spacex. Photo credit: NASA/Jim Grossmann

Programming Language Software For Graphics Applications

NASA Technical Reports Server (NTRS)

Beckman, Brian C.

1993-01-01

New approach reduces repetitive development of features common to different applications. High-level programming language and interactive environment with access to graphical hardware and software created by adding graphical commands and other constructs to standardized, general-purpose programming language, "Scheme". Designed for use in developing other software incorporating interactive computer-graphics capabilities into application programs. Provides alternative to programming entire applications in C or FORTRAN, specifically ameliorating design and implementation of complex control and data structures typifying applications with interactive graphics. Enables experimental programming and rapid development of prototype software, and yields high-level programs serving as executable versions of software-design documentation.

C-Language Integrated Production System, Version 5.1

NASA Technical Reports Server (NTRS)

Riley, Gary; Donnell, Brian; Ly, Huyen-Anh VU; Culbert, Chris; Savely, Robert T.; Mccoy, Daniel J.; Giarratano, Joseph

1992-01-01

CLIPS 5.1 provides cohesive software tool for handling wide variety of knowledge with support for three different programming paradigms: rule-based, object-oriented, and procedural. Rule-based programming provides representation of knowledge by use of heuristics. Object-oriented programming enables modeling of complex systems as modular components. Procedural programming enables CLIPS to represent knowledge in ways similar to those allowed in such languages as C, Pascal, Ada, and LISP. Working with CLIPS 5.1, one can develop expert-system software by use of rule-based programming only, object-oriented programming only, procedural programming only, or combinations of the three.

Review of NASA's Planned Mars Program

NASA Technical Reports Server (NTRS)

1996-01-01

The exploration of Mars has long been a prime scientific objective of the U.S. planetary exploration program. Yet no U.S. spacecraft has successfully made measurements at Mars since the Viking missions of the late 1970s. Mars Observer, which was designed to conduct global observations from orbit, failed just before orbit insertion in 1993. The Russian spacecraft Phobos 2 did succeed in making some observations of the planet in 1989, but it was designed primarily to observe Phobos, the innermost satellite of Mars; the spacecraft failed 2 months after insertion into Mars orbit during the complex maneuvers required to rendezvous with the martian satellite. In fall 1996 NASA plans to launch Mars Pathfinder for a landing on the martian surface in mid-1997. This spacecraft is one of the first two missions in NASA's Discovery program that inaugurates a new style of planetary exploration in which missions are low-cost (less than $150 million) and have very focused science objectives. As can be seen in the comparative data presented in Box 1, this mission is considerably smaller in terms of cost, mass, and scope than NASA's previous Mars missions. NASA's FY 1995 budget initiated a continuing Mars exploration program, called Mars Surveyor, that involves multiple launches of spacecraft as small as or smaller than Mars Pathfinder to Mars over the next several launch opportunities, which recur roughly every 26 months. The first mission in the program, Mars Global Surveyor, set for launch late in 1996, is intended to accomplish many of the objectives of the failed Mars Observer. Like the Discovery program, Mars Surveyor is a continuing series of low-cost missions, each of which has highly focused science objectives. See Box 1 for comparative details of those Surveyor missions currently defined. Around the same time that the Mars Surveyor series was chosen as the centerpiece of NASA's solar system exploration program, the Committee on Planetary and Lunar Exploration (COMPLEX) designated Mars as one of four scientific targets for emphasis in future studies. It was against this background that the Space Studies Board charged COMPLEX to review whether the Mars Pathfinder and Surveyor programs, as presently conceived, satisfy the highest priorities for understanding Mars as provided in its report, An Integrated Strategy for the Planetary Sciences: 1995-2010. The present document is COMPLEX's assessment of the scientific potential of NASA's new approach to Mars exploration. This assessment considers how well the scientific objectives of the Mars Surveyor program match those of the Integrated Strategy; it also addresses some advantages and disadvantages of the smaller-faster-cheaper approach to the exploration of Mars. The capabilities of the various instruments are not discussed in detail since the Mars Observer instruments, all of which are scheduled for reflight, have already been assessed by COMPLEX2 and later instruments are, in general, not yet well defined.

Numerical evaluation of multi-loop integrals for arbitrary kinematics with SecDec 2.0

NASA Astrophysics Data System (ADS)

Borowka, Sophia; Carter, Jonathon; Heinrich, Gudrun

2013-02-01

We present the program SecDec 2.0, which contains various new features. First, it allows the numerical evaluation of multi-loop integrals with no restriction on the kinematics. Dimensionally regulated ultraviolet and infrared singularities are isolated via sector decomposition, while threshold singularities are handled by a deformation of the integration contour in the complex plane. As an application, we present numerical results for various massive two-loop four-point diagrams. SecDec 2.0 also contains new useful features for the calculation of more general parameter integrals, related for example to phase space integrals. Program summaryProgram title: SecDec 2.0 Catalogue identifier: AEIR_v2_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/AEIR_v2_0.html Program obtainable from: CPC Program Library, Queen's University, Belfast, N. Ireland Licensing provisions: Standard CPC licence, http://cpc.cs.qub.ac.uk/licence/licence.html No. of lines in distributed program, including test data, etc.: 156829 No. of bytes in distributed program, including test data, etc.: 2137907 Distribution format: tar.gz Programming language: Wolfram Mathematica, Perl, Fortran/C++. Computer: From a single PC to a cluster, depending on the problem. Operating system: Unix, Linux. RAM: Depending on the complexity of the problem Classification: 4.4, 5, 11.1. Catalogue identifier of previous version: AEIR_v1_0 Journal reference of previous version: Comput. Phys. Comm. 182(2011)1566 Does the new version supersede the previous version?: Yes Nature of problem: Extraction of ultraviolet and infrared singularities from parametric integrals appearing in higher order perturbative calculations in gauge theories. Numerical integration in the presence of integrable singularities (e.g., kinematic thresholds). Solution method: Algebraic extraction of singularities in dimensional regularization using iterated sector decomposition. This leads to a Laurent series in the dimensional regularization parameter ɛ, where the coefficients are finite integrals over the unit hypercube. Those integrals are evaluated numerically by Monte Carlo integration. The integrable singularities are handled by choosing a suitable integration contour in the complex plane, in an automated way. Reasons for new version: In the previous version the calculation of multi-scale integrals was restricted to the Euclidean region. Now multi-loop integrals with arbitrary physical kinematics can be evaluated. Another major improvement is the possibility of full parallelization. Summary of revisions: No restriction on the kinematics for multi-loop integrals. The integrand can be constructed from the topological cuts of the diagram. Possibility of full parallelization. Numerical integration of multi-loop integrals written in C++ rather than Fortran. Possibility to loop over ranges of parameters. Restrictions: Depending on the complexity of the problem, limited by memory and CPU time. The restriction that multi-scale integrals could only be evaluated at Euclidean points is superseded in version 2.0. Running time: Between a few minutes and several days, depending on the complexity of the problem. Test runs provided take only seconds.

Publications of the exobiology program for 1984: A special bibliography

NASA Technical Reports Server (NTRS)

Wallace, J. S. (Compiler); Devincenzi, D. L. (Compiler)

1986-01-01

A bibliography of NASA exobiology programs is given. Planetary environments; chemical evolution; organic geochemistry; extraterrestrial intelligence; and the effect of planetary solar and astrophysical phenomena on the evolution of complex life in the universe are among the topics listed.

Handbook for Local Officials : Highways and Bridges

DOT National Transportation Integrated Search

2001-01-01

There are a number of funding and technical assistance programs available to the local governments in Vermont. Due to the variety of these programs and the complexities of each, this may be a confusing area for elected or appointed officials in towns...

Computer program for thin-wire structures in a homogeneous conducting medium

NASA Technical Reports Server (NTRS)

Richmond, J. H.

1974-01-01

A computer program is presented for thin-wire antennas and scatters in a homogeneous conducting medium. The anaylsis is performed in the real or complex frequency domain. The program handles insulated and bare wires with finite conductivity and lumped loads. The output data includes the current distribution, impedance, radiation efficiency, gain, absorption cross section, scattering cross section, echo area and the polarization scattering matrix. The program uses sinusoidal bases and Galerkin's method.

The Impact of a new Surgery Residency Program on Case Volume and Case Complexity in a Sub Saharan African Hospital

PubMed Central

Kendig, Claire; Tyson, Anna; Young, Sven; Mabedi, Charles; Cairns, Bruce; Charles, Anthony

2014-01-01

Background Improved access to surgical care could prevent a significant burden of disease and disability-adjusted life years (DALYs), and workforce shortages are the biggest obstacle to surgical care. To address this shortage, a 5-year surgical residency program was established at Kamuzu Central Hospital (KCH) in July 2009. As the residency enters its fourth year, we hypothesized that the initiation of a general surgical residency program would result in an increase in the overall case volume and complexity at KCH. Methods We conducted a retrospective analysis of operated cases at KCH during the three years prior to and the third year after the implementation of the KCH- Surgical residency program, from July 2006 to July 2009, and the calendar year 2012, respectively. Results During the three years prior to the initiation of the surgical residency, an average of 2317 operations were performed per year, while in 2012, 2773 operations were performed, representing a 20% increase. Pre-residency, an average of 1191 major operations per year were performed, and in 2012, 1501 major operations were performed, representing a 26% increase. Conclusion Our study demonstrates that operative case volume and complexity increases following the initiation of a surgical residency program in a sub Saharan tertiary hospital. We believe that by building on established partnerships and emphasizing education, research, and clinical care, we can start to tackle the issues of surgical access and care. PMID:25456410

Logic programming to infer complex RNA expression patterns from RNA-seq data.

PubMed

Weirick, Tyler; Militello, Giuseppe; Ponomareva, Yuliya; John, David; Döring, Claudia; Dimmeler, Stefanie; Uchida, Shizuka

2018-03-01

To meet the increasing demand in the field, numerous long noncoding RNA (lncRNA) databases are available. Given many lncRNAs are specifically expressed in certain cell types and/or time-dependent manners, most lncRNA databases fall short of providing such profiles. We developed a strategy using logic programming to handle the complex organization of organs, their tissues and cell types as well as gender and developmental time points. To showcase this strategy, we introduce 'RenalDB' (http://renaldb.uni-frankfurt.de), a database providing expression profiles of RNAs in major organs focusing on kidney tissues and cells. RenalDB uses logic programming to describe complex anatomy, sample metadata and logical relationships defining expression, enrichment or specificity. We validated the content of RenalDB with biological experiments and functionally characterized two long intergenic noncoding RNAs: LOC440173 is important for cell growth or cell survival, whereas PAXIP1-AS1 is a regulator of cell death. We anticipate RenalDB will be used as a first step toward functional studies of lncRNAs in the kidney.

Development of a software and hardware system for monitoring the air cleaning process using a cyclone-separator

NASA Astrophysics Data System (ADS)

Nicolaeva, B. K.; Borisov, A. P.; Zlochevskiy, V. L.

2017-08-01

The article is devoted to the development of a hardware-software complex for monitoring and controlling the process of air purification by means of a cyclone-separator. The hardware of this complex is the Arduino platform, to which are connected pressure sensors, air velocities, dustmeters, which allow monitoring of the main parameters of the cyclone-separator. Also, a frequency converter was developed to regulate the rotation speed of an asynchronous motor necessary to correct the flow rate, the control signals of which come with Arduino. The program part of the complex is written in the form of a web application in the programming language JavaScript and inserts into CSS and HTML for the user interface. This program allows you to receive data from sensors, build dependencies in real time and control the speed of rotation of an asynchronous electric drive. The conducted experiment shows that the cleaning efficiency is 95-99.9%, while the airflow at the cyclone inlet is 16-18 m/s, and at the exit 50-70 m/s.

Strategic Options for International Participation in Space Exploration: Lessons from U.S.-Japan Defense Cooperation

NASA Technical Reports Server (NTRS)

Hudiburg, John J.; Chinworth, Michael W.

2005-01-01

The President's Commission on Implementation of United States Space Exploration Policy suggests that after NASA establishes the Space Exploration vision architecture, it should pursue international partnerships. Two possible approaches were suggested: multiple independently operated missions and an integrated mission with carefully selected international components. The U.S.-Japan defense sectors have learned key lessons from experience with both of these approaches. U.S.-Japan defense cooperation has evolved over forty years from simple military assistance programs to more complex joint development efforts. With the evolution of the political-military alliance and the complexity of defense programs, these cooperative efforts have engaged increasingly industrial resources and capabilities as well as more sophisticated forms of planning, technology transfers and program management. Some periods of this evolution have been marked by significant frictions. The U.S.Japan FS-X program, for example, provides a poor example for management of international cooperation. In November 1988, the United States and Japan signed a Memorandum of Understanding (MOU) to co-develop an aircraft, named FS-X and later renamed F -2, as a replacement to the aging Japan support fighter F-l. The program was marked by numerous political disputes. After over a decade of joint development and testing, F -2 production deliveries finally began in 1999. The production run was curtailed due to much higher than anticipated costs and less than desired aircraft performance. One universally agreed "lesson" from the FSX/F-2 case was that it did not represent the ideal approach to bilateral cooperation. More recent cooperative programs have involved targeted joint research and development, including component development for ballistic missile defense systems. These programs could lay the basis for more ambitious cooperative efforts. This study examines both less-than-stellar international cooperation efforts as well as more successful initiatives to identify lessons from military programs that can help NASA encourage global investment in its Space Exploration Vision. The paper establishes a basis for examining related policy and industrial concerns such as effective utilization of dual-use technologies and trans-Pacific program management of large, complex cooperative programs.

A systematic grounded approach to the development of complex interventions: the Australian WorkHealth Program--arthritis as a case study.

PubMed

Reavley, Nicola; Livingston, Jenni; Buchbinder, Rachelle; Bennell, Kim; Stecki, Chris; Osborne, Richard Harry

2010-02-01

Despite demands for evidence-based research and practice, little attention has been given to systematic approaches to the development of complex interventions to tackle workplace health problems. This paper outlines an approach to the initial stages of a workplace program development which integrates health promotion and disease management. The approach commences with systematic and genuine processes of obtaining information from key stakeholders with broad experience of these interventions. This information is constructed into a program framework in which practice-based and research-informed elements are both valued. We used this approach to develop a workplace education program to reduce the onset and impact of a common chronic disease - osteoarthritis. To gain information systematically at a national level, a structured concept mapping workshop with 47 participants from across Australia was undertaken. Participants were selected to maximise the whole-of-workplace perspective and included health education providers, academics, clinicians and policymakers. Participants generated statements in response to a seeding statement: Thinking as broadly as possible, what changes in education and support should occur in the workplace to help in the prevention and management of arthritis? Participants grouped the resulting statements into conceptually coherent groups and a computer program was used to generate a 'cluster map' along with a list of statements sorted according to cluster membership. In combination with research-based evidence, the concept map informed the development of a program logic model incorporating the program's guiding principles, possible service providers, services, training modes, program elements and the causal processes by which participants might benefit. The program logic model components were further validated through research findings from diverse fields, including health education, coaching, organisational learning, workplace interventions, workforce development and osteoarthritis disability prevention. In summary, wide and genuine consultation, concept mapping, and evidence-based program logic development were integrated to develop a whole-of-system complex intervention in which potential effectiveness and assimilation into the workplace for which optimised. Copyright 2009 Elsevier Ltd. All rights reserved.

Long-Term Monitoring Network Optimization Evaluation for Operable Unit 2, Bunker Hill Mining and Metallurgical Complex Superfund Site, Idaho

EPA Pesticide Factsheets

This report presents a description and evaluation of the ground water and surface water monitoring program associated with the Bunker Hill Mining and Metallurgical Complex Superfund Site (Bunker Hill) Operable Unit (OU) 2.

Collaborative Undergraduate HBCU Student Summer Training Program Award

DTIC Science & Technology

2012-06-01

facultyTab The Wright Labo ratory is focuse d on defining the composition, activity, and overall cellul ar function of protein complexes in...overall cellul ar function of protein complexes in higher organisms. We utilize quantitative mass spectrometry as a platform to study protein

Enduring the shipboard stressor complex: a systems approach.

PubMed

Comperatore, Carlos A; Rivera, Pik Kwan; Kingsley, Leonard

2005-06-01

A high incidence of physiological and psychological stressors characterizes the maritime work environment in many segments of the commercial maritime industry and in the military. Traditionally, crewmembers work embedded in a complex of stressors. Stressors rarely act independently because most occur concurrently, simultaneously taxing physical and mental resources. Stressors such as extreme environmental temperatures, long work hours, heavy mental and physical workload, authoritative leadership, isolation from family and loved ones, lack of exercise, and unhealthy diets often combine to degrade crewmember health and performance, particularly on long voyages. This complex system of interacting stressors affects the ability of maritime crewmembers to maintain adequate levels of alertness and performance. An analytical systems approach methodology is described here as a viable method to identify workplace stressors and track their systemic interactions. A systems-based program for managing the stressor complex is then offered, together with the empirical research supporting its efficacy. Included is an example implementation of a stressor-control program aboard a U.S. Coast Guard cutter.

Enhancer Activation Requires Trans-Recruitment of a Mega Transcription Factor Complex

PubMed Central

Liu, Zhijie; Merkurjev, Daria; Yang, Feng; Li, Wenbo; Oh, Soohwan; Friedman, Meyer J.; Song, Xiaoyuan; Zhang, Feng; Ma, Qi; Ohgi, Kenneth; Krones, Anna; Rosenfeld, Michael G.

2014-01-01

Summary Enhancers provide critical information directing cell-type specific transcriptional programs, regulated by binding of signal-dependent transcription factors and their associated cofactors. Here we report that the most strongly activated estrogen (E2)-responsive enhancers are characterized by trans-recruitment and in situ assembly of a large 1-2 MDa complex of diverse DNA-binding transcription factors by ERα at ERE-containing enhancers. We refer to enhancers recruiting these factors as mega transcription factor-bound in trans (MegaTrans) enhancers. The MegaTrans complex is a signature of the most potent functional enhancers and is required for activation of enhancer RNA transcription and recruitment of coactivators, including p300 and Med1. The MegaTrans complex functions, in part, by recruiting specific enzymatic machinery, exemplified by DNA-dependent protein kinase. Thus, MegaTrans-containing enhancers represent a cohort of functional enhancers that mediate a broad and important transcriptional program and provide a molecular explanation for transcription factor clustering and hotspots noted in the genome. PMID:25303530

A case study of quality improvement methods for complex adaptive systems applied to an academic hepatology program.

PubMed

Fontanesi, John; Martinez, Anthony; Boyo, Toritsesan O; Gish, Robert

2015-01-01

Although demands for greater access to hepatology services that are less costly and achieve better outcomes have led to numerous quality improvement initiatives, traditional quality management methods may be inappropriate for hepatology. We empirically tested a model for conducting quality improvement in an academic hepatology program using methods developed to analyze and improve complex adaptive systems. We achieved a 25% increase in volume using 15% more clinical sessions with no change in staff or faculty FTEs, generating a positive margin of 50%. Wait times for next available appointments were reduced from five months to two weeks; unscheduled appointment slots dropped from 7% to less than 1%; "no-show" rates dropped to less than 10%; Press-Ganey scores increased to the 100th percentile. We conclude that framing hepatology as a complex adaptive system may improve our understanding of the complex, interdependent actions required to improve quality of care, patient satisfaction, and cost-effectiveness.

Challenges in Understanding and Forecasting Winds in Complex Terrain.

NASA Astrophysics Data System (ADS)

Mann, J.; Fernando, J.; Wilczak, J. M.

2017-12-01

An overview will be given of some of the challenges in understanding and forecasting winds in complex terrain. These challenges can occur for several different reasons including 1) gaps in our understanding of fundamental physical boundary layer processes occurring in complex terrain; 2) a lack of adequate parameterizations and/or numerical schemes in NWP models; and 3) inadequate observations for initialization of NWP model forecasts. Specific phenomena that will be covered include topographic wakes/vortices, cold pools, gap flows, and mountain-valley winds, with examples taken from several air quality and wind energy related field programs in California as well as from the recent Second Wind Forecast Improvement Program (WFIP2) field campaign in the Columbia River Gorge/Basin area of Washington and Oregon States. Recent parameterization improvements discussed will include those for boundary layer turbulence, including 3D turbulence schemes, and gravity wave drag. Observational requirements for improving wind forecasting in complex terrain will be discussed, especially in the context of forecasting pressure gradient driven gap flow events.

Fast computation of the Gauss hypergeometric function with all its parameters complex with application to the Pöschl Teller Ginocchio potential wave functions

NASA Astrophysics Data System (ADS)

Michel, N.; Stoitsov, M. V.

2008-04-01

The fast computation of the Gauss hypergeometric function F12 with all its parameters complex is a difficult task. Although the F12 function verifies numerous analytical properties involving power series expansions whose implementation is apparently immediate, their use is thwarted by instabilities induced by cancellations between very large terms. Furthermore, small areas of the complex plane, in the vicinity of z=e, are inaccessible using F12 power series linear transformations. In order to solve these problems, a generalization of R.C. Forrey's transformation theory has been developed. The latter has been successful in treating the F12 function with real parameters. As in real case transformation theory, the large canceling terms occurring in F12 analytical formulas are rigorously dealt with, but by way of a new method, directly applicable to the complex plane. Taylor series expansions are employed to enter complex areas outside the domain of validity of power series analytical formulas. The proposed algorithm, however, becomes unstable in general when |a|, |b|, |c| are moderate or large. As a physical application, the calculation of the wave functions of the analytical Pöschl-Teller-Ginocchio potential involving F12 evaluations is considered. Program summaryProgram title: hyp_2F1, PTG_wf Catalogue identifier: AEAE_v1_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/AEAE_v1_0.html Program obtainable from: CPC Program Library, Queen's University, Belfast, N. Ireland Licensing provisions: Standard CPC licence, http://cpc.cs.qub.ac.uk/licence/licence.html No. of lines in distributed program, including test data, etc.: 6839 No. of bytes in distributed program, including test data, etc.: 63 334 Distribution format: tar.gz Programming language: C++, Fortran 90 Computer: Intel i686 Operating system: Linux, Windows Word size: 64 bits Classification: 4.7 Nature of problem: The Gauss hypergeometric function F12, with all its parameters complex, is uniquely calculated in the frame of transformation theory with power series summations, thus providing a very fast algorithm. The evaluation of the wave functions of the analytical Pöschl-Teller-Ginocchio potential is treated as a physical application. Solution method: The Gauss hypergeometric function F12 verifies linear transformation formulas allowing consideration of arguments of a small modulus which then can be handled by a power series. They, however, give rise to indeterminate or numerically unstable cases, when b-a and c-a-b are equal or close to integers. They are properly dealt with through analytical manipulations of the Lanczos expression providing the Gamma function. The remaining zones of the complex plane uncovered by transformation formulas are dealt with Taylor expansions of the F12 function around complex points where linear transformations can be employed. The Pöschl-Teller-Ginocchio potential wave functions are calculated directly with F12 evaluations. Restrictions: The algorithm provides full numerical precision in almost all cases for |a|, |b|, and |c| of the order of one or smaller, but starts to be less precise or unstable when they increase, especially through a, b, and c imaginary parts. While it is possible to run the code for moderate or large |a|, |b|, and |c| and obtain satisfactory results for some specified values, the code is very likely to be unstable in this regime. Unusual features: Two different codes, one for the hypergeometric function and one for the Pöschl-Teller-Ginocchio potential wave functions, are provided in C++ and Fortran 90 versions. Running time: 20,000 F12 function evaluations take an average of one second.

Kennedy Space Center Director Update

NASA Image and Video Library

2014-03-06

CAPE CANAVERAL, Fla. - Community leaders, business executives, educators, and state and local government leaders were updated on NASA Kennedy Space Center programs and accomplishments during Center Director Bob Cabana’s Center Director Update at the Debus Center at the Kennedy Space Center Visitor Complex in Florida. Attendees mingled and visited various displays, including Ground Systems Development and Operations Program and Education Office displays. Attendees talked with Cabana and other senior Kennedy managers and visited displays featuring updates on Kennedy programs and projects, including International Space Station, Commercial Crew, Ground System Development and Operations, Launch Services, Center Planning and Development, Technology, KSC Swamp Works and NASA Education. The morning concluded with a tour of the new Space Shuttle Atlantis exhibit at the visitor complex. For more information, visit http://www.nasa.gov/kennedy. Photo credit: NASA/Daniel Casper

Kennedy Space Center Director Update

NASA Image and Video Library

2014-03-06

CAPE CANAVERAL, Fla. - Community leaders, business executives, educators, and state and local government leaders were updated on NASA Kennedy Space Center programs and accomplishments during Center Director Bob Cabana’s Center Director Update at the Debus Center at the Kennedy Space Center Visitor Complex in Florida. An attendee talks with Scott Thurston, Kennedy deputy of the spacecraft office at the Commercial Crew Program display. Attendees talked with Cabana and other senior Kennedy managers and visited displays featuring updates on Kennedy programs and projects, including International Space Station, Commercial Crew, Ground System Development and Operations, Launch Services, Center Planning and Development, Technology, KSC Swamp Works and NASA Education. The morning concluded with a tour of the new Space Shuttle Atlantis exhibit at the visitor complex. For more information, visit http://www.nasa.gov/kennedy. Photo credit: NASA/Daniel Casper

Northeast regional and state trends in anuran occupancy from calling survey data (2001-2011) from the North American Amphibian Monitoring Program

USGS Publications Warehouse

Weir, Linda A.; Royle, Andy; Gazenski, Kimberly D.; Villena Carpio, Oswaldo

2014-01-01

We present the first regional trends in anuran occupancy from North American Amphibian Monitoring Program (NAAMP) data from 11 northeastern states using an 11 years of data. NAAMP is a long-term monitoring program where observers collect data at assigned random roadside routes using a calling survey technique. We assessed occupancy trends for 17 species. Eight species had statistically significant regional trends, of these seven were negative (Anaxyrus fowleri, Acris crepitans, Pseudacris brachyphona, Pseudacris feriarum-kalmi complex, Lithobates palustris, Lithobates pipiens, and Lithobates sphenocephalus) and one was positive (Hyla versicolor-chrysoscelis complex). We also assessed state level trends for 101 species/state combinations, of these 29 showed a significant decline and nine showed a significant increase in occupancy.

From vision to reality: strategic agility in complex times.

PubMed

Soule, Barbara M

2002-04-01

Health care is experiencing turbulent times. Change has become the constant. Complexity and sometimes chaos are common characteristics. Within this context, infection control professionals strive to maintain their practices, achieve excellence, and plan for the future. As demands shift and expectations increase, professionals in infection surveillance, prevention, and control (ISPC) programs must develop strategic agility. This article describes the rationale for strategic thinking and action set within a framework of 6 thought-provoking questions. It also describes a number of techniques to use for thinking strategically, such as designing visions, becoming entrepreneurial, and engaging in creative and futuristic exercises to evaluate possibilities for program direction. These techniques can guide individual professionals or ISPC programs in strategic decision-making that will increase the ability to survive and succeed in the future.

Programming Chemical Reaction Networks Using Intramolecular Conformational Motions of DNA.

PubMed

Lai, Wei; Ren, Lei; Tang, Qian; Qu, Xiangmeng; Li, Jiang; Wang, Lihua; Li, Li; Fan, Chunhai; Pei, Hao

2018-06-22

The programmable regulation of chemical reaction networks (CRNs) represents a major challenge toward the development of complex molecular devices performing sophisticated motions and functions. Nevertheless, regulation of artificial CRNs is generally energy- and time-intensive as compared to natural regulation. Inspired by allosteric regulation in biological CRNs, we herein develop an intramolecular conformational motion strategy (InCMS) for programmable regulation of DNA CRNs. We design a DNA switch as the regulatory element to program the distance between the toehold and branch migration domain. The presence of multiple conformational transitions leads to wide-range kinetic regulation spanning over 4 orders of magnitude. Furthermore, the process of energy-cost-free strand exchange accompanied by conformational change discriminates single base mismatches. Our strategy thus provides a simple yet effective approach for dynamic programming of complex CRNs.

Use of RORA for Complex Ground-Water Flow Conditions

USGS Publications Warehouse

Rutledge, A.T.

2004-01-01

The RORA computer program for estimating recharge is based on a condition in which ground water flows perpendicular to the nearest stream that receives ground-water discharge. The method, therefore, does not explicitly account for the ground-water-flow component that is parallel to the stream. Hypothetical finite-difference simulations are used to demonstrate effects of complex flow conditions that consist of two components: one that is perpendicular to the stream and one that is parallel to the stream. Results of the simulations indicate that the RORA program can be used if certain constraints are applied in the estimation of the recession index, an input variable to the program. These constraints apply to a mathematical formulation based on aquifer properties, recession of ground-water levels, and recession of streamflow.

Complexity: an internet resource for analysis of DNA sequence complexity

PubMed Central

Orlov, Y. L.; Potapov, V. N.

2004-01-01

The search for DNA regions with low complexity is one of the pivotal tasks of modern structural analysis of complete genomes. The low complexity may be preconditioned by strong inequality in nucleotide content (biased composition), by tandem or dispersed repeats or by palindrome-hairpin structures, as well as by a combination of all these factors. Several numerical measures of textual complexity, including combinatorial and linguistic ones, together with complexity estimation using a modified Lempel–Ziv algorithm, have been implemented in a software tool called ‘Complexity’ (http://wwwmgs.bionet.nsc.ru/mgs/programs/low_complexity/). The software enables a user to search for low-complexity regions in long sequences, e.g. complete bacterial genomes or eukaryotic chromosomes. In addition, it estimates the complexity of groups of aligned sequences. PMID:15215465

Using Systems Thinking in the Design, Implementation, and Evaluation of Complex Educational Innovations, with Examples from the InTeGrate Project

ERIC Educational Resources Information Center

Kastens, Kim A.; Manduca, Cathryn A.

2017-01-01

Many geoscience education initiatives now involve cross-departmental or multi-institutional programs. However, the geoscientists who lead such programs typically have little experience or training in program design, leadership, or evaluation. In this commentary, we make the case that geoscientists taking on these ambitious leadership roles can…

The Impact of Structural Barriers and Facilitators on Early Childhood Literacy Programs in Elementary Charter Schools

ERIC Educational Resources Information Center

Ross, Denise; Pinder, Glen; Coles-White, D'Jaris

2015-01-01

Elementary charter schools increasingly serve students who are at-risk for reading challenges, giving them a critical role in establishing literacy for young children. This article examines the complexities of starting early childhood literacy programs in charter schools. Specifically, the first year of K-3 literacy programs in a new and a…

More Time or Better Tools? A Large-Scale Retrospective Comparison of Pedagogical Approaches to Teach Programming

ERIC Educational Resources Information Center

Silva-Maceda, Gabriela; Arjona-Villicaña, P. David; Castillo-Barrera, F. Edgar

2016-01-01

Learning to program is a complex task, and the impact of different pedagogical approaches to teach this skill has been hard to measure. This study examined the performance data of seven cohorts of students (N = 1168) learning programming under three different pedagogical approaches. These pedagogical approaches varied either in the length of the…

Effects of a Case-Based Reasoning System on Student Performance in a Java Programming Course

ERIC Educational Resources Information Center

Schmidt, Cecil

2007-01-01

The purpose of this study was to determine if a case-based reasoning tool would improve a student's understanding of the complex concepts in a Java programming course. Subjects for the study were randomly assigned from two sections of an introductory Java programming course. Posttests were used to measure the effects of the case-based reasoning…

Exploring Self-Esteem in a Girls' Sports Program: Competencies and Connections Create Change

ERIC Educational Resources Information Center

Markowitz, Ellen

2012-01-01

Self-esteem has been problematic for researchers because it is complex, stable, and hard to measure. When assessing the self-esteem of out-of-school time (OST) program participants, some researchers may think their instruments will not detect changes, either because the program does not last long enough to make a difference or because self-esteem…

Capturing Complexity: Integrating Health and Education Research to Inform Health-Promoting Schools Policy and Practice

ERIC Educational Resources Information Center

Rowling, Louise; Jeffreys, Vicki

2006-01-01

Despite the intersectoral nature of health promotion practice many programs limit their evidence base to health sector research and do not draw on evidence from other sectors' research in program design. To help ensure programs are relevant and acceptable to intersectoral partners and intended outcomes are of value to all sectors involved,…

Security Assistance Dependence - Wielding American Power

DTIC Science & Technology

2002-12-09

national security objectives. One vehicle of this power brokering is the well-developed international security assistance program – oftentimes...incorrectly referred to exclusively as foreign military sales. There is nothing simple about the security assistance program as it has developed today...For the USG, there are many agencies influencing today’s security assistance program to execute complex, integrated tasks directly impacting U.S

Is Pair Programming More Effective than Solo Programming for Secondary Education Novice Programmers? A Case Study

ERIC Educational Resources Information Center

Papadakis, Stamatios

2018-01-01

The teaching and learning of programming are often considered a difficult topic for both teachers and students, due to its complexity and abstract nature. The traditional teaching approaches are unable to contribute substantially to the development of the necessary cognitive models by the students, producing high rates of failure and dropout in…

Nurse manager orientation.

PubMed

Hawkins, Anne; Carter, Kelly; Nugent, Mary

2009-01-01

On the basis of the principles of management and leadership, our organization has worked over the years to formalize the orientation program for new nurse managers. This program meets the needs of new nurse managers and responds to today's complex health care system needs. This article describes the components of a nurse manager orientation program for the novice nurse manager and methods for evaluating nurse manager effectiveness.

Report of the Cost Assessment and Validation Task Force on the International Space Station

NASA Technical Reports Server (NTRS)

1998-01-01

The Cost Assessment and Validation (CAV) Task Force was established for independent review and assessment of cost, schedule and partnership performance on the International Space Station (ISS) Program. The CAV Task Force has made the following key findings: The International Space Station Program has made notable and reasonable progress over the past four years in defining and executing a very challenging and technically complex effort. The Program size, complexity, and ambitious schedule goals were beyond that which could be reasonably achieved within the $2.1 billion annual cap or $17.4 billion total cap. A number of critical risk elements are likely to have an adverse impact on the International Space Station cost and schedule. The schedule uncertainty associated with Russian implementation of joint Partnership agreements is the major threat to the ISS Program. The Fiscal Year (FY) 1999 budget submission to Congress is not adequate to execute the baseline ISS Program, cover normal program growth, and address the known critical risks. Additional annual funding of between $130 million and $250 million will be required. Completion of ISS assembly is likely to be delayed from one to three years beyond December 2003.

Cost Assessment and Validation Task Force on the International Space Station

NASA Technical Reports Server (NTRS)

1998-01-01

The Cost Assessment and Validation (CAV) Task Force was established for independent review and assessment of cost, schedule and partnership performance on the International Space Station (ISS) Program. The CAV Task Force has made the following key findings: The International Space Station Program has made notable and reasonable progress over the past four years in defining and executing a very challenging and technically complex effort; The Program, size, complexity, and ambitious schedule goals were beyond that which could be reasonably achieved within the $2.1 billion annual cap or $17.4 billion total cap; A number of critical risk elements are likely to have an adverse impact on the International Space Station cost and schedule; The schedule uncertainty associated with Russian implementation of joint Partnership agreements is the major threat to the ISS Program; The Fiscal Year (FY) 1999 budget submission to Congress is not adequate to execute the baseline ISS Program, cover normal program, growth, and address the known critical risks. Additional annual funding of between $130 million and $250 million will be required; and Completion of ISS assembly is likely to be delayed from, one to three years beyond December 2003.

Palingol: a declarative programming language to describe nucleic acids' secondary structures and to scan sequence database.

PubMed Central

Billoud, B; Kontic, M; Viari, A

1996-01-01

At the DNA/RNA level, biological signals are defined by a combination of spatial structures and sequence motifs. Until now, few attempts had been made in writing general purpose search programs that take into account both sequence and structure criteria. Indeed, the most successful structure scanning programs are usually dedicated to particular structures and are written using general purpose programming languages through a complex and time consuming process where the biological problem of defining the structure and the computer engineering problem of looking for it are intimately intertwined. In this paper, we describe a general representation of structures, suitable for database scanning, together with a programming language, Palingol, designed to manipulate it. Palingol has specific data types, corresponding to structural elements-basically helices-that can be arranged in any way to form a complex structure. As a consequence of the declarative approach used in Palingol, the user should only focus on 'what to search for' while the language engine takes care of 'how to look for it'. Therefore, it becomes simpler to write a scanning program and the structural constraints that define the required structure are more clearly identified. PMID:8628670

House Calls: California Program For Homebound Patients Reduces Monthly Spending, Delivers Meaningful Care.

PubMed

Melnick, Glenn A; Green, Lois; Rich, Jeremy

2016-01-01

In 2009 HealthCare Partners Affiliates Medical Group, based in Southern California, launched House Calls, an in-home program that provides, coordinates, and manages care primarily for recently discharged high-risk, frail, and psychosocially compromised patients. Its purpose is to reduce preventable emergency department visits and hospital readmissions. We present data over time from this well-established program to provide an example for other new programs that are being established across the United States to serve this population with complex needs. The findings show that the initial House Calls structure, staffing patterns, and processes differed across the geographic areas that it served, and that they also evolved over time in different ways. In the same time period, all areas experienced a reduction in operating costs per patient and showed substantial reductions in monthly per patient health care spending and hospital utilization after enrollment in the House Calls program, compared to the period before enrollment. Despite more than five years of experience, the program structure continues to evolve and adjust staffing and other features to accommodate the dynamic nature of this complex patient population. Project HOPE—The People-to-People Health Foundation, Inc.

Integrating design science theory and methods to improve the development and evaluation of health communication programs.

PubMed

Neuhauser, Linda; Kreps, Gary L

2014-12-01

Traditional communication theory and research methods provide valuable guidance about designing and evaluating health communication programs. However, efforts to use health communication programs to educate, motivate, and support people to adopt healthy behaviors often fail to meet the desired goals. One reason for this failure is that health promotion issues are complex, changeable, and highly related to the specific needs and contexts of the intended audiences. It is a daunting challenge to effectively influence health behaviors, particularly culturally learned and reinforced behaviors concerning lifestyle factors related to diet, exercise, and substance (such as alcohol and tobacco) use. Too often, program development and evaluation are not adequately linked to provide rapid feedback to health communication program developers so that important revisions can be made to design the most relevant and personally motivating health communication programs for specific audiences. Design science theory and methods commonly used in engineering, computer science, and other fields can address such program and evaluation weaknesses. Design science researchers study human-created programs using tightly connected build-and-evaluate loops in which they use intensive participatory methods to understand problems and develop solutions concurrently and throughout the duration of the program. Such thinking and strategies are especially relevant to address complex health communication issues. In this article, the authors explore the history, scientific foundation, methods, and applications of design science and its potential to enhance health communication programs and their evaluation.

Context, Challenges, and Tensions in Global Efforts to Engage Men in the Prevention of Violence against Women: An Ecological Analysis

PubMed Central

Casey, Erin A.; Carlson, Juliana; Fraguela-Rios, Cathlyn; Kimball, Ericka; Neugut, Tova B.; Tolman, Richard M.; Edleson, Jeffrey L.

2014-01-01

As gender-based violence prevention programs around the world increasingly include efforts to engage men and boys as antiviolence allies, both the profound benefits and the inherent complexities of these efforts are emerging. Acknowledging and exploring tensions associated with engaging men is an important element of thoughtfully fostering men’s antiviolence ally movements so as to both respectfully invite men into anti-violence work and create effective, gender-equitable prevention programming. To this end, this study presents descriptive findings regarding challenges associated with men’s engagement programming from in-depth interviews with twenty-nine representatives of organizations that engage men and boys in preventing violence against women and girls in Africa, Asia, Europe, Oceania, and North and South America. Programs reported negotiating complex issues related to gender, the intersectional nature of men’s identities, and establishing legitimacy and sustainability within communities while maintaining ideological focus and consistency. Additionally, programs reported that these tensions manifest across ecological layers of analysis, and impact both the participation of individual men and the programs’ experiences in community and national contexts. PMID:25568612

Aspect-Oriented Programming

NASA Technical Reports Server (NTRS)

Elrad, Tzilla (Editor); Filman, Robert E. (Editor); Bader, Atef (Editor)

2001-01-01

Computer science has experienced an evolution in programming languages and systems from the crude assembly and machine codes of the earliest computers through concepts such as formula translation, procedural programming, structured programming, functional programming, logic programming, and programming with abstract data types. Each of these steps in programming technology has advanced our ability to achieve clear separation of concerns at the source code level. Currently, the dominant programming paradigm is object-oriented programming - the idea that one builds a software system by decomposing a problem into objects and then writing the code of those objects. Such objects abstract together behavior and data into a single conceptual and physical entity. Object-orientation is reflected in the entire spectrum of current software development methodologies and tools - we have OO methodologies, analysis and design tools, and OO programming languages. Writing complex applications such as graphical user interfaces, operating systems, and distributed applications while maintaining comprehensible source code has been made possible with OOP. Success at developing simpler systems leads to aspirations for greater complexity. Object orientation is a clever idea, but has certain limitations. We are now seeing that many requirements do not decompose neatly into behavior centered on a single locus. Object technology has difficulty localizing concerns invoking global constraints and pandemic behaviors, appropriately segregating concerns, and applying domain-specific knowledge. Post-object programming (POP) mechanisms that look to increase the expressiveness of the OO paradigm are a fertile arena for current research. Examples of POP technologies include domain-specific languages, generative programming, generic programming, constraint languages, reflection and metaprogramming, feature-oriented development, views/viewpoints, and asynchronous message brokering. (Czarneclu and Eisenecker s book includes a good survey of many of these technologies).

3′ fragment of miR173-programmed RISC-cleaved RNA is protected from degradation in a complex with RISC and SGS3

PubMed Central

Yoshikawa, Manabu; Iki, Taichiro; Tsutsui, Yasuhiro; Miyashita, Kyoko; Poethig, R. Scott; Habu, Yoshiki; Ishikawa, Masayuki

2013-01-01

trans-acting small interfering RNAs (tasiRNAs) are plant-specific endogenous siRNAs produced via a unique pathway whose first step is the microRNA (miRNA)-programmed RNA-induced silencing complex (RISC)–mediated cleavage of tasiRNA gene (TAS) transcripts. One of the products is subsequently transformed into tasiRNAs by a pathway that requires several factors including SUPPRESSOR OF GENE SILENCING3 (SGS3) and RNA-DEPENDENT RNA POLYMERASE6. Here, using in vitro assembled ARGONAUTE (AGO)1–RISCs, we show that SGS3 is recruited onto RISCs only when they bind target RNA. Following cleavage by miRNA173 (miR173)-programmed RISC, SGS3 was found in complexes containing cleaved TAS2 RNA and RISC. The 3′ cleavage fragment (the source of tasiRNAs) was protected from degradation in this complex. Depletion of SGS3 did not affect TAS2 RNA cleavage by miR173-programmed RISC, but did affect the stability of the 3′ cleavage fragment. When the 3′ nucleotide of 22-nt miR173 was deleted or the corresponding nucleotide in TAS2 RNA was mutated, the complex was not observed and the 3′ cleavage fragment was degraded. Importantly, these changes in miR173 or TAS2 RNA are known to lead to a loss of tasiRNA production in vivo. These results suggest that (i) SGS3 associates with AGO1–RISC via the double-stranded RNA formed by the 3′-terminal nucleotides of 22-nt miR173 and corresponding target RNA, which probably protrudes from the AGO1–RISC molecular surface, (ii) SGS3 protects the 3′ cleavage fragment of TAS2 RNA from degradation, and (iii) the observed SGS3-dependent stabilization of the 3′ fragment of TAS2 RNA is key to tasiRNA production. PMID:23417299

3' fragment of miR173-programmed RISC-cleaved RNA is protected from degradation in a complex with RISC and SGS3.

PubMed

Yoshikawa, Manabu; Iki, Taichiro; Tsutsui, Yasuhiro; Miyashita, Kyoko; Poethig, R Scott; Habu, Yoshiki; Ishikawa, Masayuki

2013-03-05

trans-acting small interfering RNAs (tasiRNAs) are plant-specific endogenous siRNAs produced via a unique pathway whose first step is the microRNA (miRNA)-programmed RNA-induced silencing complex (RISC)-mediated cleavage of tasiRNA gene (TAS) transcripts. One of the products is subsequently transformed into tasiRNAs by a pathway that requires several factors including SUPPRESSOR OF GENE SILENCING3 (SGS3) and RNA-DEPENDENT RNA POLYMERASE6. Here, using in vitro assembled ARGONAUTE (AGO)1-RISCs, we show that SGS3 is recruited onto RISCs only when they bind target RNA. Following cleavage by miRNA173 (miR173)-programmed RISC, SGS3 was found in complexes containing cleaved TAS2 RNA and RISC. The 3' cleavage fragment (the source of tasiRNAs) was protected from degradation in this complex. Depletion of SGS3 did not affect TAS2 RNA cleavage by miR173-programmed RISC, but did affect the stability of the 3' cleavage fragment. When the 3' nucleotide of 22-nt miR173 was deleted or the corresponding nucleotide in TAS2 RNA was mutated, the complex was not observed and the 3' cleavage fragment was degraded. Importantly, these changes in miR173 or TAS2 RNA are known to lead to a loss of tasiRNA production in vivo. These results suggest that (i) SGS3 associates with AGO1-RISC via the double-stranded RNA formed by the 3'-terminal nucleotides of 22-nt miR173 and corresponding target RNA, which probably protrudes from the AGO1-RISC molecular surface, (ii) SGS3 protects the 3' cleavage fragment of TAS2 RNA from degradation, and (iii) the observed SGS3-dependent stabilization of the 3' fragment of TAS2 RNA is key to tasiRNA production.

48 CFR 48.102 - Policies.

Code of Federal Regulations, 2011 CFR

2011-10-01

... systems research and development except where the contracting officer determines and documents the file to... prime contractor has demonstrated an effective VE program during either earlier program phases, or...: (1) Extent of the change. (2) Complexity of the change. (3) Development risk (e.g., contractor's...

Challenges for Curriculum Leadership in Contemporary Teacher Education

ERIC Educational Resources Information Center

Parkes, Robert J.

2013-01-01

This paper outlines the complex contemporary milieu of Australian teacher education within which curriculum leaders responsible for designing teacher education programs must make their program design decisions. Particular attention is paid to the collision of vertical ("hierarchical" or "academic rationalist") and horizontal…

Introduction to symposium: Arthropods and wildlife conservation: synergy in complex biological systems

USDA-ARS?s Scientific Manuscript database

The symposium will discuss the effects of arthropods and other stressors on wildlife conservation programs. Speakers with affiliations in wildlife biology, parasitology and entomology will be included in the program. Research of national and international interest will be presented....

Rx for Tutor Training.

ERIC Educational Resources Information Center

Rubenstein, Ilene; And Others

Tutor training programs in composition which emphasize interpersonal skills while offering concentrated correctness doses of mechanics and grammar are inherently limiting. While interpersonal skills are important, they only superficially address the complex situation of tutoring. A prescription for a healthy tutor program, one which would allow…

An Integrated Constraint Programming Approach to Scheduling Sports Leagues with Divisional and Round-robin Tournaments

DOE Office of Scientific and Technical Information (OSTI.GOV)

Carlsson, Mats; Johansson, Mikael; Larson, Jeffrey

Previous approaches for scheduling a league with round-robin and divisional tournaments involved decomposing the problem into easier subproblems. This approach, used to schedule the top Swedish handball league Elitserien, reduces the problem complexity but can result in suboptimal schedules. This paper presents an integrated constraint programming model that allows to perform the scheduling in a single step. Particular attention is given to identifying implied and symmetry-breaking constraints that reduce the computational complexity significantly. The experimental evaluation of the integrated approach takes considerably less computational effort than the previous approach.

Social cohesion through football: a quasi-experimental mixed methods design to evaluate a complex health promotion program

PubMed Central

2010-01-01

Social isolation and disengagement fragments local communities. Evidence indicates that refugee families are highly vulnerable to social isolation in their countries of resettlement. Research to identify approaches to best address this is needed. Football United is a program that aims to foster social inclusion and cohesion in areas with high refugee settlement in New South Wales, Australia, through skills and leadership development, mentoring, and the creation of links with local community and corporate leaders and organisations. The Social Cohesion through Football study's broad goal is to examine the implementation of a complex health promotion program, and to analyse the processes involved in program implementation. The study will consider program impact on individual health and wellbeing, social inclusion and cohesion, as well as analyse how the program by necessity interacts and adapts to context during implementation, a concept we refer to as plasticity. The proposed study will be the first prospective cohort impact study to our knowledge to assess the impact of a comprehensive integrated program using football as a vehicle for fostering social inclusion and cohesion in communities with high refugee settlement. Methods/design A quasi-experimental cohort study design with treatment partitioning involving four study sites. The study employs a 'dose response' model, comparing those with no involvement in the Football United program with those with lower or higher levels of participation. A range of qualitative and quantitative measures will be used in the study. Study participants' emotional well being, resilience, ethnic identity and other group orientation, feelings of social inclusion and belonging will be measured using a survey instrument complemented by relevant data drawn from in-depth interviews, self reporting measures and participant observation. The views of key informants from the program and the wider community will also be solicited. Discussion The complexity of the Football United program poses challenges for measurement, and requires the study design to be responsive to the dynamic nature of the program and context. Assessment of change is needed at multiple levels, drawing on mixed methods and multidisciplinary approaches in implementation and evaluation. Attention to these challenges has underpinned the design and methods in the Social Cohesion through Football study, which will use a unique and innovative combination of measures that have not been applied together previously in social inclusion/cohesion and sport and social inclusion/cohesion program research. PMID:20920361

Social cohesion through football: a quasi-experimental mixed methods design to evaluate a complex health promotion program.

PubMed

Nathan, Sally; Bunde-Birouste, Anne; Evers, Clifton; Kemp, Lynn; MacKenzie, Julie; Henley, Robert

2010-10-05

Social isolation and disengagement fragments local communities. Evidence indicates that refugee families are highly vulnerable to social isolation in their countries of resettlement. Research to identify approaches to best address this is needed. Football United is a program that aims to foster social inclusion and cohesion in areas with high refugee settlement in New South Wales, Australia, through skills and leadership development, mentoring, and the creation of links with local community and corporate leaders and organisations. The Social Cohesion through Football study's broad goal is to examine the implementation of a complex health promotion program, and to analyse the processes involved in program implementation. The study will consider program impact on individual health and wellbeing, social inclusion and cohesion, as well as analyse how the program by necessity interacts and adapts to context during implementation, a concept we refer to as plasticity. The proposed study will be the first prospective cohort impact study to our knowledge to assess the impact of a comprehensive integrated program using football as a vehicle for fostering social inclusion and cohesion in communities with high refugee settlement. A quasi-experimental cohort study design with treatment partitioning involving four study sites. The study employs a 'dose response' model, comparing those with no involvement in the Football United program with those with lower or higher levels of participation. A range of qualitative and quantitative measures will be used in the study. Study participants' emotional well being, resilience, ethnic identity and other group orientation, feelings of social inclusion and belonging will be measured using a survey instrument complemented by relevant data drawn from in-depth interviews, self reporting measures and participant observation. The views of key informants from the program and the wider community will also be solicited. The complexity of the Football United program poses challenges for measurement, and requires the study design to be responsive to the dynamic nature of the program and context. Assessment of change is needed at multiple levels, drawing on mixed methods and multidisciplinary approaches in implementation and evaluation. Attention to these challenges has underpinned the design and methods in the Social Cohesion through Football study, which will use a unique and innovative combination of measures that have not been applied together previously in social inclusion/cohesion and sport and social inclusion/cohesion program research.

A programmable optimization environment using the GAMESS-US and MERLIN/MCL packages. Applications on intermolecular interaction energies

NASA Astrophysics Data System (ADS)

Kalatzis, Fanis G.; Papageorgiou, Dimitrios G.; Demetropoulos, Ioannis N.

2006-09-01

The Merlin/MCL optimization environment and the GAMESS-US package were combined so as to offer an extended and efficient quantum chemistry optimization system, capable of implementing complex optimization strategies for generic molecular modeling problems. A communication and data exchange interface was established between the two packages exploiting all Merlin features such as multiple optimizers, box constraints, user extensions and a high level programming language. An important feature of the interface is its ability to perform dimer computations by eliminating the basis set superposition error using the counterpoise (CP) method of Boys and Bernardi. Furthermore it offers CP-corrected geometry optimizations using analytic derivatives. The unified optimization environment was applied to construct portions of the intermolecular potential energy surface of the weakly bound H-bonded complex C 6H 6-H 2O by utilizing the high level Merlin Control Language. The H-bonded dimer HF-H 2O was also studied by CP-corrected geometry optimization. The ab initio electronic structure energies were calculated using the 6-31G ** basis set at the Restricted Hartree-Fock and second-order Moller-Plesset levels, while all geometry optimizations were carried out using a quasi-Newton algorithm provided by Merlin. Program summaryTitle of program: MERGAM Catalogue identifier:ADYB_v1_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/ADYB_v1_0 Program obtainable from: CPC Program Library, Queen's University of Belfast, N. Ireland Computer for which the program is designed and others on which it has been tested: The program is designed for machines running the UNIX operating system. It has been tested on the following architectures: IA32 (Linux with gcc/g77 v.3.2.3), AMD64 (Linux with the Portland group compilers v.6.0), SUN64 (SunOS 5.8 with the Sun Workshop compilers v.5.2) and SGI64 (IRIX 6.5 with the MIPSpro compilers v.7.4) Installations: University of Ioannina, Greece Operating systems or monitors under which the program has been tested: UNIX Programming language used: ANSI C, ANSI Fortran-77 No. of lines in distributed program, including test data, etc.:11 282 No. of bytes in distributed program, including test data, etc.: 49 458 Distribution format: tar.gz Memory required to execute with typical data: Memory requirements mainly depend on the selection of a GAMESS-US basis set and the number of atoms No. of bits in a word: 32 No. of processors used: 1 Has the code been vectorized or parallelized?: no Nature of physical problem: Multidimensional geometry optimization is of great importance in any ab initio calculation since it usually is one of the most CPU-intensive tasks, especially on large molecular systems. For example, the geometric and energetic description of van der Waals and weakly bound H-bonded complexes requires the construction of related important portions of the multidimensional intermolecular potential energy surface (IPES). So the various held views about the nature of these bonds can be quantitatively tested. Method of solution: The Merlin/MCL optimization environment was interconnected with the GAMESS-US package to facilitate geometry optimization in quantum chemistry problems. The important portions of the IPES require the capability to program optimization strategies. The Merlin/MCL environment was used for the implementation of such strategies. In this work, a CP-corrected geometry optimization was performed on the HF-H 2O complex and an MCL program was developed to study portions of the potential energy surface of the C 6H 6-H 2O complex. Restrictions on the complexity of the problem: The Merlin optimization environment and the GAMESS-US package must be installed. The MERGAM interface requires GAMESS-US input files that have been constructed in Cartesian coordinates. This restriction occurs from a design-time requirement to not allow reorientation of atomic coordinates; this rule holds always true when applying the COORD = UNIQUE keyword in a GAMESS-US input file. Typical running time: It depends on the size of the molecular system, the size of the basis set and the method of electron correlation. Execution of the test run took approximately 5 min on a 2.8 GHz Intel Pentium CPU.

Acquisition Program Lead Systems Integration/Lead Capabilities Integration Decision Support Methodology and Tool

DTIC Science & Technology

2015-04-30

from the MIT Sloan School that provide a relative complexity score for functions (Product and Context Complexity). The PMA assesses the complexity...collection of information is estimated to average 1 hour per response, including the time for reviewing instructions, searching existing data sources...gathering and maintaining the data needed, and completing and reviewing the collection of information. Send comments regarding this burden estimate or

DORMAN computer program (study 2.5). Volume 2: User's guide and programmer's guide. [development of data bank for computerized information storage of NASA programs

NASA Technical Reports Server (NTRS)

Wray, S. T., Jr.

1973-01-01

The DORMAN program was developed to create and modify a data bank containing data decks which serve as input to the DORCA Computer Program. Via a remote terminal a user can access the bank, extract any data deck, modify that deck, output the modified deck to be input to the DORCA program, and save the modified deck in the data bank. This computer program is an assist in the utilization of the DORCA program. The program is dimensionless and operates almost entirely in integer mode. The program was developed on the CDC 6400/7600 complex for implementation on a UNIVAC 1108 computer.

Cx-02 Program, workshop on modeling complex systems

USGS Publications Warehouse

Mossotti, Victor G.; Barragan, Jo Ann; Westergard, Todd D.

2003-01-01

This publication contains the abstracts and program for the workshop on complex systems that was held on November 19-21, 2002, in Reno, Nevada. Complex systems are ubiquitous within the realm of the earth sciences. Geological systems consist of a multiplicity of linked components with nested feedback loops; the dynamics of these systems are non-linear, iterative, multi-scale, and operate far from equilibrium. That notwithstanding, It appears that, with the exception of papers on seismic studies, geology and geophysics work has been disproportionally underrepresented at regional and national meetings on complex systems relative to papers in the life sciences. This is somewhat puzzling because geologists and geophysicists are, in many ways, preadapted to thinking of complex system mechanisms. Geologists and geophysicists think about processes involving large volumes of rock below the sunlit surface of Earth, the accumulated consequence of processes extending hundreds of millions of years in the past. Not only do geologists think in the abstract by virtue of the vast time spans, most of the evidence is out-of-sight. A primary goal of this workshop is to begin to bridge the gap between the Earth sciences and life sciences through demonstration of the universality of complex systems science, both philosophically and in model structures.

Chemical Frustration. A Design Principle for the Discovery of New Complex Alloy and Intermetallic Phases, Final Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fredrickson, Daniel C

2015-06-23

Final technical report for "Chemical Frustration: A Design Principle for the Discovery of New Complex Alloy and Intermetallic Phases" funded by the Office of Science through the Materials Chemistry Program of the Office of Basic Energy Sciences.

Helping Your Students To Understand Complex Social Problems.

ERIC Educational Resources Information Center

Valentine, Tom, Ed.; Sandlin, Jenny, Ed.

1998-01-01

This document, which was developed to assist individuals working in publicly sponsored literacy programs in Georgia, offers instructional plans and practical strategies designed to help teachers help students of adult literacy, adult basic education, General Educational Development, and English as a second language understand complex social…

Evaluating Educational Interventions That Induce Service Receipt: A Case Study Application of "City Connects"

ERIC Educational Resources Information Center

Bowden, A. Brooks; Shand, Robert; Belfield, Clive R.; Wang, Anyi; Levin, Henry M.

2017-01-01

Educational interventions are complex: Often they combine a diagnostic component (identifying student need) with a service component (ensuring appropriate educational resources are provided). This complexity raises challenges for program evaluation. These interventions, which we refer to as "service mediation interventions," affect…

Navigating Complexities: An Integrative Approach to English Language Teacher Education

ERIC Educational Resources Information Center

Ryan, Phillip; Glodjo, Tyler; Hobbs, Bethany; Stargel, Victoria; Williams, Thad

2015-01-01

This article is an analysis of one undergraduate English language teacher education program's integrative theoretical framework that is structured around three pillars: interdisciplinarity, critical pedagogy, and teacher exploration. First, the authors survey the unique complexities of language teaching and learning. Then, they introduce this…

Developmental problems and their solution for the Space Shuttle main engine alternate liquid oxygen high-pressure turbopump: Anomaly or failure investigation the key

NASA Astrophysics Data System (ADS)

Ryan, R.; Gross, L. A.

1995-05-01

The Space Shuttle main engine (SSME) alternate high-pressure liquid oxygen pump experienced synchronous vibration and ball bearing life problems that were program threatening. The success of the program hinged on the ability to solve these development problems. The design and solutions to these problems are engirded in the lessons learned and experiences from prior programs, technology programs, and the ability to properly conduct failure or anomaly investigations. The failure investigation determines the problem cause and is the basis for recommending design solutions. For a complex problem, a comprehensive solution requires that formal investigation procedures be used, including fault trees, resolution logic, and action items worked through a concurrent engineering-multidiscipline team. The normal tendency to use an intuitive, cut-and-try approach will usually prove to be costly, both in money and time and will reach a less than optimum, poorly understood answer. The SSME alternate high-pressure oxidizer turbopump development has had two complex problems critical to program success: (1) high synchronous vibrations and (2) excessive ball bearing wear. This paper will use these two problems as examples of this formal failure investigation approach. The results of the team's investigation provides insight into the complexity of the turbomachinery technical discipline interacting/sensitivities and the fine balance of competing investigations required to solve problems and guarantee program success. It is very important to the solution process that maximum use be made of the resources that both the contractor and Government can bring to the problem in a supporting and noncompeting way. There is no place for the not-invented-here attitude. The resources include, but are not limited to: (1) specially skilled professionals; (2) supporting technologies; (3) computational codes and capabilities; and (4) test and manufacturing facilities.

KSC-05PD-1267

NASA Technical Reports Server (NTRS)

2005-01-01

KENNEDY SPACE CENTER, FLA. This is Launch Complex 5/6 blockhouse, now a museum at the Cape Canaveral Air Force Station (CCAFS) in Florida, where long-lost space suits were found. A recent venture into a long-locked room at CCAFS uncovered interesting artifacts of a bygone era: retired space suits from Americans who trained in the 1960s to be astronauts aboard an Air Force orbiting reconnaissance laboratory. Two security officers were doing a check of a facility at Launch Complex 5/6 blockhouse. NASA Special Agent Dan E. Oakland and Security Manager Henry Butler, who is with Delaware North Parks and Resorts, the company that oversees the museum, discovered a locked room. Space suits from the Air Forces planned Manned Orbiting Laboratory (MOL) program were found in the room Begun in 1964, the MOL program was an Air Force initiative that would have sent Air Force astronauts to a space station in a Gemini capsule. After spending a few weeks in orbit, the crew would undock and return to Earth. A test launch from Complex 40 on Nov. 30, 1966, of a MOL was conducted with an unmanned Gemini capsule. The MOL was constructed from tankage of a Titan II rocket. The operational MOL was planned to be launched into a polar orbit from Vandenberg Air Force Base in California. The Air Force abandoned the program in 1969, but the program produced a great deal of technological development, and three groups of military officers trained to be MOL astronauts. When the program was cancelled, seven of the younger astronauts were transferred to the agencys human space flight program and went on to have standout careers. Among them were Robert Crippen, pilot of the first Space Shuttle mission, and Richard H. 'Dick' Truly, who later became NASA Administrator.

KSC-05PD-1274

NASA Technical Reports Server (NTRS)

2005-01-01

KENNEDY SPACE CENTER, FLA. This is Launch Complex 5/6 blockhouse, now a museum at the Cape Canaveral Air Force Station (CCAFS) in Florida, where long-lost spacesuits were found. A recent venture into a long-locked room at CCAFS uncovered interesting artifacts of a bygone era: retired space suits from Americans who trained in the 1960s to be astronauts aboard an Air Force orbiting reconnaissance laboratory. Two security officers were doing a check of a facility at Launch Complex 5/6 blockhouse. NASA Special Agent Dan E. Oakland and Security Manager Henry Butler, with Delaware North Parks and Resorts, which oversees the museum, discovered a locked room. Space suits from the Air Forces planned Manned Orbiting Laboratory (MOL) program were found in the room Begun in 1964, the MOL program was an Air Force initiative that would have sent Air Force astronauts to a space station in a Gemini capsule. After spending a few weeks in orbit, the crew would undock and return to Earth. A test launch from Complex 40 on Nov. 30, 1966, of a MOL was conducted with an unmanned Gemini capsule. The MOL was constructed from tankage of a Titan II rocket. The operational MOL was planned to be launched into a polar orbit from Vandenberg Air Force Base in California. The Air Force abandoned the program in 1969, but the program produced a great deal of technological development, and three groups of military officers trained to be MOL astronauts. When the program was cancelled, seven of the younger astronauts were transferred to the agencys human space flight program and went on to have standout careers. Among them were Robert Crippen, pilot of the first Space Shuttle mission, and Richard H. 'Dick' Truly, who later became NASA Administrator.

Fetal programming alters reactive oxygen species production in sheep cardiac mitochondria.

PubMed

von Bergen, Nicholas H; Koppenhafer, Stacia L; Spitz, Douglas R; Volk, Kenneth A; Patel, Sonali S; Roghair, Robert D; Lamb, Fred S; Segar, Jeffrey L; Scholz, Thomas D

2009-04-01

Exposure to an adverse intrauterine environment is recognized as an important risk factor for the development of cardiovascular disease later in life. Although oxidative stress has been proposed as a mechanism for the fetal programming phenotype, the role of mitochondrial O(2)(*-) (superoxide radical) production has not been explored. To determine whether mitochondrial ROS (reactive oxygen species) production is altered by in utero programming, pregnant ewes were given a 48-h dexamethasone (dexamethasone-exposed, 0.28 mg.kg(-1) of body weight.day(-1)) or saline (control) infusion at 27-28 days gestation (term=145 days). Intact left ventricular mitochondria and freeze-thaw mitochondrial membranes were studied from offspring at 4-months of age. AmplexRed was used to measure H(2)O(2) production. Activities of the antioxidant enzymes Mn-SOD (manganese superoxide dismutase), GPx (glutathione peroxidase) and catalase were measured. Compared with controls, a significant increase in Complex I H(2)O(2) production was found in intact mitochondria from dexamethasone-exposed animals. The treatment differences in Complex I-driven H(2)O(2) production were not seen in mitochondrial membranes. Consistent changes in H(2)O(2) production from Complex III in programmed animals were not found. Despite the increase in H(2)O(2) production in intact mitochondria from programmed animals, dexamethasone exposure significantly increased mitochondrial catalase activity, whereas Mn-SOD and GPx activities were unchanged. The results of the present study point to an increase in the rate of release of H(2)O(2) from programmed mitochondria despite an increase in catalase activity. Greater mitochondrial H(2)O(2) release into the cell may play a role in the development of adult disease following exposure to an adverse intrauterine environment.

Developmental problems and their solution for the Space Shuttle main engine alternate liquid oxygen high-pressure turbopump: Anomaly or failure investigation the key

NASA Technical Reports Server (NTRS)

Ryan, R.; Gross, L. A.

1995-01-01

The Space Shuttle main engine (SSME) alternate high-pressure liquid oxygen pump experienced synchronous vibration and ball bearing life problems that were program threatening. The success of the program hinged on the ability to solve these development problems. The design and solutions to these problems are engirded in the lessons learned and experiences from prior programs, technology programs, and the ability to properly conduct failure or anomaly investigations. The failure investigation determines the problem cause and is the basis for recommending design solutions. For a complex problem, a comprehensive solution requires that formal investigation procedures be used, including fault trees, resolution logic, and action items worked through a concurrent engineering-multidiscipline team. The normal tendency to use an intuitive, cut-and-try approach will usually prove to be costly, both in money and time and will reach a less than optimum, poorly understood answer. The SSME alternate high-pressure oxidizer turbopump development has had two complex problems critical to program success: (1) high synchronous vibrations and (2) excessive ball bearing wear. This paper will use these two problems as examples of this formal failure investigation approach. The results of the team's investigation provides insight into the complexity of the turbomachinery technical discipline interacting/sensitivities and the fine balance of competing investigations required to solve problems and guarantee program success. It is very important to the solution process that maximum use be made of the resources that both the contractor and Government can bring to the problem in a supporting and noncompeting way. There is no place for the not-invented-here attitude. The resources include, but are not limited to: (1) specially skilled professionals; (2) supporting technologies; (3) computational codes and capabilities; and (4) test and manufacturing facilities.

A pilot study of Aboriginal health promotion from an ecological perspective

PubMed Central

2011-01-01

Background For health promotion to be effective in Aboriginal and Torres Strait Islander Communities, interventions (and their evaluation) need to work within a complex social environment and respect Indigenous knowledge, culture and social systems. At present, there is a lack of culturally appropriate evaluation methods available to practitioners that are capable of capturing this complexity. As an initial response to this problem, we used two non-invasive methods to evaluate a community-directed health promotion program, which aimed to improve nutrition and physical activity for members of the Aboriginal community of the Goulburn-Murray region of northern Victoria, Australia. The study addressed two main questions. First, for members of an Aboriginal sporting club, what changes were made to the nutrition environment in which they meet and how is this related to national guidelines for minimising the risk of chronic disease? Second, to what degree was the overall health promotion program aligned with an ecological model of health promotion that addresses physical, social and policy environments as well as individual knowledge and behaviour? Methods Rather than monitoring individual outcomes, evaluation methods reported on here assessed change in the nutrition environment (sports club food supply) as a facilitator of dietary change and the 'ecological' nature of the overall program (that is, its complexity with respect to numbers of targets, settings and strategies). Results There were favourable changes towards the provision of a food supply consistent with Australian guidelines at the sports club. The ecological analysis indicated that the design and implementation of the program were consistent with an ecological model of health promotion. Conclusions The evaluation was useful for assessing the impact of the program on the nutrition environment and for understanding the ecological nature of program activities. PMID:21961906

Developing an active implementation model for a chronic disease management program.

PubMed

Smidth, Margrethe; Christensen, Morten Bondo; Olesen, Frede; Vedsted, Peter

2013-04-01

Introduction and diffusion of new disease management programs in healthcare is usually slow, but active theory-driven implementation seems to outperform other implementation strategies. However, we have only scarce evidence on the feasibility and real effect of such strategies in complex primary care settings where municipalities, general practitioners and hospitals should work together. The Central Denmark Region recently implemented a disease management program for chronic obstructive pulmonary disease (COPD) which presented an opportunity to test an active implementation model against the usual implementation model. The aim of the present paper is to describe the development of an active implementation model using the Medical Research Council's model for complex interventions and the Chronic Care Model. We used the Medical Research Council's five-stage model for developing complex interventions to design an implementation model for a disease management program for COPD. First, literature on implementing change in general practice was scrutinised and empirical knowledge was assessed for suitability. In phase I, the intervention was developed; and in phases II and III, it was tested in a block- and cluster-randomised study. In phase IV, we evaluated the feasibility for others to use our active implementation model. The Chronic Care Model was identified as a model for designing efficient implementation elements. These elements were combined into a multifaceted intervention, and a timeline for the trial in a randomised study was decided upon in accordance with the five stages in the Medical Research Council's model; this was captured in a PaTPlot, which allowed us to focus on the structure and the timing of the intervention. The implementation strategies identified as efficient were use of the Breakthrough Series, academic detailing, provision of patient material and meetings between providers. The active implementation model was tested in a randomised trial (results reported elsewhere). The combination of the theoretical model for complex interventions and the Chronic Care Model and the chosen specific implementation strategies proved feasible for a practice-based active implementation model for a chronic-disease-management-program for COPD. Using the Medical Research Council's model added transparency to the design phase which further facilitated the process of implementing the program. http://www.clinicaltrials.gov/(NCT01228708).

Investigating the adiabatic beam grouping at the NICA accelerator complex

NASA Astrophysics Data System (ADS)

Brovko, O. I.; Butenko, A. V.; Grebentsov, A. Yu.; Eliseev, A. V.; Meshkov, I. N.; Svetov, A. L.; Sidorin, A. O.; Slepnev, V. M.

2016-12-01

The NICA complex comprises the Booster and Nuclotron synchrotrons for accelerating particle beams to the required energy and the Collider machine, in which particle collisions are investigated. The experimental heavy-ion program deals with ions up to Au+79. The light-ion program deals with polarized deuterons and protons. Grouping of a beam coasting in an ion chamber is required in many parts of the complex. Beam grouping may effectively increase the longitudinal emittance and particle losses. To avoid these negative effects, various regimes of adiabatic grouping have been simulated and dedicated experiments with a deuteron beam have been conducted at the Nuclotron machine. As a result, we are able to construct and optimize the beam-grouping equipment, which provides a capture efficiency near 100% either retaining or varying the harmonic multiplicity of the HF system.

Emergence of a learning community: a transforming experience at the boundaries

NASA Astrophysics Data System (ADS)

Raia, Federica

2013-03-01

I narrate a process of transformation, a professional and personal journey framed by an experience that captured my attention shaping my interpretation and reflections. From a critical complexity framework I discuss the emergence of a learning community from the cooperation among individuals of diverse social and cultural worlds sharing the need to change a traditional professional development program structure and develop a new science education Masters Degree/Certification program. I zoom into the continual redefinition of the community, its evolution and complex interrelations among its participants and the emergence of a learning community as a boundary space having an emancipatory role and allowing growth and learning. I analyze the dialectical relationship between agents' behavior either impeding growth or having an emancipatory function of a mindful RelationalAct in a complex adaptive system framework.

Electrical Programming of Soft Matter: Using Temporally Varying Electrical Inputs To Spatially Control Self Assembly.

PubMed

Yan, Kun; Liu, Yi; Zhang, Jitao; Correa, Santiago O; Shang, Wu; Tsai, Cheng-Chieh; Bentley, William E; Shen, Jana; Scarcelli, Giuliano; Raub, Christopher B; Shi, Xiao-Wen; Payne, Gregory F

2018-02-12

The growing importance of hydrogels in translational medicine has stimulated the development of top-down fabrication methods, yet often these methods lack the capabilities to generate the complex matrix architectures observed in biology. Here we show that temporally varying electrical signals can cue a self-assembling polysaccharide to controllably form a hydrogel with complex internal patterns. Evidence from theory and experiment indicate that internal structure emerges through a subtle interplay between the electrical current that triggers self-assembly and the electrical potential (or electric field) that recruits and appears to orient the polysaccharide chains at the growing gel front. These studies demonstrate that short sequences (minutes) of low-power (∼1 V) electrical inputs can provide the program to guide self-assembly that yields hydrogels with stable, complex, and spatially varying structure and properties.

The content of goals in individual educational programs for students with complex communication needs.

PubMed

Klang, Nina; Rowland, Charity; Fried-Oken, Melanie; Steiner, Sandra; Granlund, Mats; Adolfsson, Margareta

2016-01-01

The aim of the study was to explore the contents of communication-related goals in individualized education programs (IEPs) for students with complex communication needs. Goals in 43 IEPs were linked to the International Classification of Functioning, Disability and Health, Children and Youth version (ICF-CY). The results show that the communication-related IEP goals contain information on multiple domains of functioning in the ICF-CY. However, judging by the amount of codes linked to ICF-CY chapters, the IEPs contain a relatively small proportion of goals that focus on interaction with others, or participation in classroom and leisure activities. Special education teachers and speech-language pathologists working with students with complex communication needs may need support to formulate communication-related IEP goals with a focus on interaction and participation in school activities.

Structure solution of DNA-binding proteins and complexes with ARCIMBOLDO libraries

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pröpper, Kevin; Instituto de Biologia Molecular de Barcelona; Meindl, Kathrin

2014-06-01

The structure solution of DNA-binding protein structures and complexes based on the combination of location of DNA-binding protein motif fragments with density modification in a multi-solution frame is described. Protein–DNA interactions play a major role in all aspects of genetic activity within an organism, such as transcription, packaging, rearrangement, replication and repair. The molecular detail of protein–DNA interactions can be best visualized through crystallography, and structures emphasizing insight into the principles of binding and base-sequence recognition are essential to understanding the subtleties of the underlying mechanisms. An increasing number of high-quality DNA-binding protein structure determinations have been witnessed despite themore » fact that the crystallographic particularities of nucleic acids tend to pose specific challenges to methods primarily developed for proteins. Crystallographic structure solution of protein–DNA complexes therefore remains a challenging area that is in need of optimized experimental and computational methods. The potential of the structure-solution program ARCIMBOLDO for the solution of protein–DNA complexes has therefore been assessed. The method is based on the combination of locating small, very accurate fragments using the program Phaser and density modification with the program SHELXE. Whereas for typical proteins main-chain α-helices provide the ideal, almost ubiquitous, small fragments to start searches, in the case of DNA complexes the binding motifs and DNA double helix constitute suitable search fragments. The aim of this work is to provide an effective library of search fragments as well as to determine the optimal ARCIMBOLDO strategy for the solution of this class of structures.« less

Evaluation of a Specialized Yoga Program for Persons Admitted to a Complex Continuing Care Hospital: A Pilot Study

PubMed Central

Kuluski, Kerry; Bechsgaard, Gitte; Ridgway, Jennifer; Katz, Joel

2016-01-01

Introduction. The purpose of this study was to evaluate a specialized yoga intervention for inpatients in a rehabilitation and complex continuing care hospital. Design. Single-cohort repeated measures design. Methods. Participants (N = 10) admitted to a rehabilitation and complex continuing care hospital were recruited to participate in a 50–60 min Hatha Yoga class (modified for wheelchair users/seated position) once a week for eight weeks, with assigned homework practice. Questionnaires on pain (pain, pain interference, and pain catastrophizing), psychological variables (depression, anxiety, and experiences with injustice), mindfulness, self-compassion, and spiritual well-being were collected at three intervals: pre-, mid-, and post-intervention. Results. Repeated measures ANOVAs revealed a significant main effect of time indicating improvements over the course of the yoga program on the (1) anxiety subscale of the Hospital Anxiety and Depression Scale, F(2,18) = 4.74, p < .05, and η p 2 = .35, (2) Self-Compassion Scale-Short Form, F(2,18) = 3.71, p < .05, and η p 2 = .29, and (3) Magnification subscale of the Pain Catastrophizing Scale, F(2,18) = 3. 66, p < .05, and η p 2 = .29. Discussion. The results suggest that an 8-week Hatha Yoga program improves pain-related factors and psychological experiences in individuals admitted to a rehabilitation and complex continuing care hospital. PMID:28115969

Directing folding pathways for multi-component DNA origami nanostructures with complex topology

NASA Astrophysics Data System (ADS)

Marras, A. E.; Zhou, L.; Kolliopoulos, V.; Su, H.-J.; Castro, C. E.

2016-05-01

Molecular self-assembly has become a well-established technique to design complex nanostructures and hierarchical mesoscale assemblies. The typical approach is to design binding complementarity into nucleotide or amino acid sequences to achieve the desired final geometry. However, with an increasing interest in dynamic nanodevices, the need to design structures with motion has necessitated the development of multi-component structures. While this has been achieved through hierarchical assembly of similar structural units, here we focus on the assembly of topologically complex structures, specifically with concentric components, where post-folding assembly is not feasible. We exploit the ability to direct folding pathways to program the sequence of assembly and present a novel approach of designing the strand topology of intermediate folding states to program the topology of the final structure, in this case a DNA origami slider structure that functions much like a piston-cylinder assembly in an engine. The ability to program the sequence and control orientation and topology of multi-component DNA origami nanostructures provides a foundation for a new class of structures with internal and external moving parts and complex scaffold topology. Furthermore, this work provides critical insight to guide the design of intermediate states along a DNA origami folding pathway and to further understand the details of DNA origami self-assembly to more broadly control folding states and landscapes.

Prenatal alcohol exposure and cellular differentiation: a role for Polycomb and Trithorax group proteins in FAS phenotypes?

PubMed

Veazey, Kylee J; Muller, Daria; Golding, Michael C

2013-01-01

Exposure to alcohol significantly alters the developmental trajectory of progenitor cells and fundamentally compromises tissue formation (i.e., histogenesis). Emerging research suggests that ethanol can impair mammalian development by interfering with the execution of molecular programs governing differentiation. For example, ethanol exposure disrupts cellular migration, changes cell-cell interactions, and alters growth factor signaling pathways. Additionally, ethanol can alter epigenetic mechanisms controlling gene expression. Normally, lineage-specific regulatory factors (i.e., transcription factors) establish the transcriptional networks of each new cell type; the cell's identity then is maintained through epigenetic alterations in the way in which the DNA encoding each gene becomes packaged within the chromatin. Ethanol exposure can induce epigenetic changes that do not induce genetic mutations but nonetheless alter the course of fetal development and result in a large array of patterning defects. Two crucial enzyme complexes--the Polycomb and Trithorax proteins--are central to the epigenetic programs controlling the intricate balance between self-renewal and the execution of cellular differentiation, with diametrically opposed functions. Prenatal ethanol exposure may disrupt the functions of these two enzyme complexes, altering a crucial aspect of mammalian differentiation. Characterizing the involvement of Polycomb and Trithorax group complexes in the etiology of fetal alcohol spectrum disorders will undoubtedly enhance understanding of the role that epigenetic programming plays in this complex disorder.

WWW Case Study Program To Enhance Thinking, Critically and Globally: The Impact of NAFTA on the Apparel Industry.

ERIC Educational Resources Information Center

Frey, Diane K.; Eckman, Molly

1999-01-01

An interactive Web program was developed to present a case study on textile/apparel products for a family and consumer sciences course. Students found the case studies relevant and stimulating for complex thinking. (SK)

77 FR 2730 - Agency Forms Undergoing Paperwork Reduction Act Review

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-19

...-Evaluation Assessments of Nutrition, Physical Activity and Obesity Programs and Policies--New--National... Prevention (CDC). Background and Brief Description The causes of obesity in the United States are complex and... jurisdictions funded through CDC's Nutrition, Physical Activity and Obesity (NPAO) cooperative agreement program...

Toward a Signature Pedagogy in Educational Leadership Preparation and Program Assessment

ERIC Educational Resources Information Center

Black, William R.; Murtadha, Khaula

2007-01-01

In this article, we work towards developing a signature pedagogy for educational leadership preparation programs. A signature pedagogy that engenders theory-building processes and leadership practices includes complex case studies, inquiry-centered internships, collaborative and interdisciplinary leadership institutes, and continuous assessments…

The Application of Science and Technology to Public Programs.

ERIC Educational Resources Information Center

Feller, Irwin

Conference papers, recommendations, and discussion are compiled, focusing on the complex of problems associated with rapidly expanding urbanization and consequent rural dislocation. Topics exploring the problems included: air and water pollution; program planning and management; solid waste disposal; transportation; housing; crime control; health…

An enhanced cluster analysis program with bootstrap significance testing for ecological community analysis

USGS Publications Warehouse

McKenna, J.E.

2003-01-01

The biosphere is filled with complex living patterns and important questions about biodiversity and community and ecosystem ecology are concerned with structure and function of multispecies systems that are responsible for those patterns. Cluster analysis identifies discrete groups within multivariate data and is an effective method of coping with these complexities, but often suffers from subjective identification of groups. The bootstrap testing method greatly improves objective significance determination for cluster analysis. The BOOTCLUS program makes cluster analysis that reliably identifies real patterns within a data set more accessible and easier to use than previously available programs. A variety of analysis options and rapid re-analysis provide a means to quickly evaluate several aspects of a data set. Interpretation is influenced by sampling design and a priori designation of samples into replicate groups, and ultimately relies on the researcher's knowledge of the organisms and their environment. However, the BOOTCLUS program provides reliable, objectively determined groupings of multivariate data.

Applying the 15 Public Health Emergency Preparedness Capabilities to Support Large-Scale Tuberculosis Investigations in Complex Congregate Settings

PubMed Central

Toren, Katelynne Gardner; Elsenboss, Carina; Narita, Masahiro

2017-01-01

Public Health—Seattle and King County, a metropolitan health department in western Washington, experiences rates of tuberculosis (TB) that are 1.6 times higher than are state and national averages. The department’s TB Control Program uses public health emergency management tools and capabilities sustained with Centers for Disease Control and Prevention grant funding to manage large-scale complex case investigations. We have described 3 contact investigations in large congregate settings that the TB Control Program conducted in 2015 and 2016. The program managed the investigations using public health emergency management tools, with support from the Preparedness Program. The 3 investigations encompassed medical evaluation of more than 1600 people, used more than 100 workers, identified nearly 30 individuals with latent TB infection, and prevented an estimated 3 cases of active disease. These incidents exemplify how investments in public health emergency preparedness can enhance health outcomes in traditional areas of public health. PMID:28892445

CMM Data Analysis Tool

DOE Office of Scientific and Technical Information (OSTI.GOV)

Due to the increase in the use of Coordinate Measuring Machines (CMMs) to measure fine details and complex geometries in manufacturing, many programs have been made to compile and analyze the data. These programs typically require extensive setup to determine the expected results in order to not only track the pass/fail of a dimension, but also to use statistical process control (SPC). These extra steps and setup times have been addressed through the CMM Data Analysis Tool, which only requires the output of the CMM to provide both pass/fail analysis on all parts run to the same inspection program asmore » well as provide graphs which help visualize where the part measures within the allowed tolerances. This provides feedback not only to the customer for approval of a part during development, but also to machining process engineers to identify when any dimension is drifting towards an out of tolerance condition during production. This program can handle hundreds of parts with complex dimensions and will provide an analysis within minutes.« less

A package for 3-D unstructured grid generation, finite-element flow solution and flow field visualization

NASA Technical Reports Server (NTRS)

Parikh, Paresh; Pirzadeh, Shahyar; Loehner, Rainald

1990-01-01

A set of computer programs for 3-D unstructured grid generation, fluid flow calculations, and flow field visualization was developed. The grid generation program, called VGRID3D, generates grids over complex configurations using the advancing front method. In this method, the point and element generation is accomplished simultaneously, VPLOT3D is an interactive, menudriven pre- and post-processor graphics program for interpolation and display of unstructured grid data. The flow solver, VFLOW3D, is an Euler equation solver based on an explicit, two-step, Taylor-Galerkin algorithm which uses the Flux Corrected Transport (FCT) concept for a wriggle-free solution. Using these programs, increasingly complex 3-D configurations of interest to aerospace community were gridded including a complete Space Transportation System comprised of the space-shuttle orbitor, the solid-rocket boosters, and the external tank. Flow solutions were obtained on various configurations in subsonic, transonic, and supersonic flow regimes.

A sophisticated cad tool for the creation of complex models for electromagnetic interaction analysis

NASA Astrophysics Data System (ADS)

Dion, Marc; Kashyap, Satish; Louie, Aloisius

1991-06-01

This report describes the essential features of the MS-DOS version of DIDEC-DREO, an interactive program for creating wire grid, surface patch, and cell models of complex structures for electromagnetic interaction analysis. It uses the device-independent graphics library DIGRAF and the graphics kernel system HALO, and can be executed on systems with various graphics devices. Complicated structures can be created by direct alphanumeric keyboard entry, digitization of blueprints, conversion form existing geometric structure files, and merging of simple geometric shapes. A completed DIDEC geometric file may then be converted to the format required for input to a variety of time domain and frequency domain electromagnetic interaction codes. This report gives a detailed description of the program DIDEC-DREO, its installation, and its theoretical background. Each available interactive command is described. The associated program HEDRON which generates simple geometric shapes, and other programs that extract the current amplitude data from electromagnetic interaction code outputs, are also discussed.

Optimization Research of Generation Investment Based on Linear Programming Model

NASA Astrophysics Data System (ADS)

Wu, Juan; Ge, Xueqian

Linear programming is an important branch of operational research and it is a mathematical method to assist the people to carry out scientific management. GAMS is an advanced simulation and optimization modeling language and it will combine a large number of complex mathematical programming, such as linear programming LP, nonlinear programming NLP, MIP and other mixed-integer programming with the system simulation. In this paper, based on the linear programming model, the optimized investment decision-making of generation is simulated and analyzed. At last, the optimal installed capacity of power plants and the final total cost are got, which provides the rational decision-making basis for optimized investments.

KSC-07pd1528

NASA Image and Video Library

2007-06-16

KENNEDY SPACE CENTER, FLA. -- This panoramic view of Space Launch Complex 36 on Cape Canaveral Air Force Station shows the two mobile service towers on the ground after their demolition. The old towers are being toppled as part of the ongoing project to demolish the historic site to prevent corrosion from becoming a safety concern. A majority of the steel will be recycled and the rest will be taken to the landfill at CCAFS. Complex 36 was the birthplace of NASA's planetary launch program. It was built for the Atlas/Centaur development program and was operated under NASA's sponsorship until the late 1980s. Complex 36 hosted many historic missions over the years including Surveyor that landed on the moon and Mariner that orbited Mars and included one to Mercury. Two of the most historic launches were the Pioneer 10 and 11 space probes that were launched to Jupiter and are now outside of the solar system in interstellar space. Also, the historic Pioneer Venus spacecraft included an orbiter and a set of probes that were dispatched to the surface. While Launch Complex 36 is gone, the Atlas/Centaur rocket continues to be launched as the Atlas V from Complex 41. Photo credit: NASA/Charisse Nahser

KSC-07pd1520

NASA Image and Video Library

2007-06-16

KENNEDY SPACE CENTER, FLA. -- At Space Launch Complex 36 on Cape Canaveral Air Force Station, the 209-foot-tall mobile service tower on Pad 36-B has been identified for demolition. The old towers are being toppled as part of the ongoing project to demolish the historic site to prevent corrosion from becoming a safety concern. A majority of the steel will be recycled and the rest will be taken to the landfill at CCAFS. Complex 36 was the birthplace of NASA's planetary launch program. It was built for the Atlas/Centaur development program and was operated under NASA's sponsorship until the late 1980s. Complex 36 hosted many historic missions over the years including Surveyor that landed on the moon and Mariner that orbited Mars and included one to Mercury. Two of the most historic launches were the Pioneer 10 and 11 space probes that were launched to Jupiter and are now outside of the solar system in interstellar space. Also, the historic Pioneer Venus spacecraft included an orbiter and a set of probes that were dispatched to the surface. While Launch Complex 36 is gone, the Atlas/Centaur rocket continues to be launched as the Atlas V from Complex 41. Photo credit: NASA/Charisse Nahser

Capturing, Codifying and Scoring Complex Data for Innovative, Computer-Based Items.

ERIC Educational Resources Information Center

Luecht, Richard M.

The Microsoft Certification Program (MCP) includes many new computer-based item types, based on complex cases involving the Windows 2000 (registered) operating system. This Innovative Item Technology (IIT) has presented challenges beyond traditional psychometric considerations such as capturing and storing the relevant response data from…

Multiheteromacrocycles that Complex Metal Ions. Fourth Progress Report, 1 May 1977 -- 30 April 1978

DOE R&D Accomplishments Database

Cram, D. J.

1978-01-15

Results are reported in a program to design, synthesize, and evaluate polycyclic host organic compounds for their abilities to complex and lipophilize guest metal ions. Work during the reporting period was devoted to synthesis and study of cyclohexametaphenylenes and cyclic phosphine oxides. (JRD)

Intervention Fidelity for a Complex Behaviour Change Intervention in Community Pharmacy Addressing Cardiovascular Disease Risk

ERIC Educational Resources Information Center

McNamara, K. P.; O'Reilly, S. L.; George, J.; Peterson, G. M.; Jackson, S. L.; Duncan, G.; Howarth, H.; Dunbar, J. A.

2015-01-01

Background: Delivery of cardiovascular disease (CVD) prevention programs by community pharmacists appears effective and enhances health service access. However, their capacity to implement complex behavioural change processes during patient counselling remains largely unexplored. This study aims to determine intervention fidelity by pharmacists…

A Program of Continuing Research on Representing, Manipulating, and Reasoning about Physical Objects

DTIC Science & Technology

1991-09-30

graphics with the goal of automatically converting complex graphics models into forms more appropriate for radiosity computation. 2.4 Least Constraint We...to computer graphics with the goal of automatically 7 converting complex graphics models into forms more appropriate for radiosity com- putation. 8 4

What can one sample tell us? Stable isotopes can assess complex processes in national assessments of lakes, rivers and streams.

EPA Science Inventory

Stable isotopes can be very useful in large-scale monitoring programs because samples for isotopic analysis are easy to collect, and isotopes integrate information about complex processes such as evaporation from water isotopes and denitrification from nitrogen isotopes. Traditi...

Developmental Evaluation: Applying Complexity Concepts to Enhance Innovation and Use

ERIC Educational Resources Information Center

Patton, Michael Quinn

2010-01-01

Developmental evaluation (DE) offers a powerful approach to monitoring and supporting social innovations by working in partnership with program decision makers. In this book, eminent authority shows how to conduct evaluations within a DE framework. Patton draws on insights about complex dynamic systems, uncertainty, nonlinearity, and emergence. He…

Complex Teacher Evaluation Systems Can Produce Negative Perceptions

ERIC Educational Resources Information Center

Schumacher, Gary

2010-01-01

The purpose of this study was to determine teacher perceptions of the impact on instructional practice when using a complex, standards-based performance evaluation system. The study used expectancy theory to investigate teacher expectancy (did they believe they could enhance their practice to the identified program standards?), instrumentality…

Programming model for distributed intelligent systems

NASA Technical Reports Server (NTRS)

Sztipanovits, J.; Biegl, C.; Karsai, G.; Bogunovic, N.; Purves, B.; Williams, R.; Christiansen, T.

1988-01-01

A programming model and architecture which was developed for the design and implementation of complex, heterogeneous measurement and control systems is described. The Multigraph Architecture integrates artificial intelligence techniques with conventional software technologies, offers a unified framework for distributed and shared memory based parallel computational models and supports multiple programming paradigms. The system can be implemented on different hardware architectures and can be adapted to strongly different applications.

Direct Loans. An Assessment of the Clinton Administration's Proposals and Some Suggestions for Improvement. AGB Public Policy Series, No. 93-1.

ERIC Educational Resources Information Center

Hauptman, Arthur M.

1993-01-01

In 1992 the Clinton Administration proposed phasing out the federally guaranteed student loan program and replacing it with a direct lending program run entirely by the federal government, claiming that this approach would save taxpayer money and simplify a complex program. Opponents of the Administration plan argued instead for changes in federal…

A Safety Program that Integrated Behavior-Based Safety and Traditional Safety Methods and Its Effects on Injury Rates of Manufacturing Workers

ERIC Educational Resources Information Center

Hermann, Jaime A.; Ibarra, Guillermo V.; Hopkins, B. L.

2010-01-01

The present research examines the effects of a complex safety program that combined Behavior-Based Safety (BBS) and traditional safety methods. The study was conducted in an automobile parts plant in Mexico. Two sister plants served as comparison. Some of the components of the safety programs addressed behaviors of managers and included methods…

NIM: A Game-Playing Program. Artificial Intelligence Memo Number 254.

ERIC Educational Resources Information Center

Papert, Seymour; Solomon, Cynthia

Students learned to plan and write complex computer programs by writing a program for playing NIM, a game in which two players alternatively remove one, two, or three sticks from an original pile of 21, with the player taking the last one being the winner. The primary teaching purpose was to develop the idea that a final goal--i.e., winning--could…

Medicaid's Complex Goals: Challenges for Managed Care and Behavioral Health

PubMed Central

Gold, Marsha; Mittler, Jessica

2000-01-01

The Medicaid program has become increasingly complex as policymakers use it to address various policy objectives, leading to structural tensions that surface with Medicaid managed care. In this article, we illustrate this complexity by focusing on the experience of three States with behavioral health carveouts—Maryland, Oregon, and Tennessee. Converting to Medicaid managed care forces policymakers to confront Medicaid's competing policy objectives, multiplicity of stakeholders, and diverse patients, many with complex needs. Emerging Medicaid managed care systems typically represent compromises in which existing inequities and fragmentation are reconfigured rather than eliminated. PMID:12500322

The Role of the New mTOR Complex, MTORC2, in Autism Spectrum Disorders

DTIC Science & Technology

2014-10-01

AWARD NUMBER: W81XWH-13-1-0380 TITLE: “The Role of the New mTOR complex, MTORC2, in Autism Spectrum Disorders” PRINCIPAL INVESTIGATOR: Mauro...THE NEW MTOR COMPLEX, MTORC2, IN AUTISM SPECTRUM DISORDERS” 5a. CONTRACT NUMBER 5b. GRANT NUMBER W81XWH-13-1-0380 5c. PROGRAM ELEMENT NUMBER 6...Distribution Unlimited 13. SUPPLEMENTARY NOTES 14. ABSTRACT The goal of my DOD-supported research is determine the role of the new mTOR complex (mTORC2) in

KSC-2012-3034a

NASA Image and Video Library

2012-05-23

CAPE CANAVERAL, Fla. – Engineers board a NASA Railroad train in preparation for its departure from the NASA Railroad Yard at NASA’s Kennedy Space Center in Florida. The train is headed for the Florida East Coast Railway interchange in Titusville, Fla., where the train’s helium tank cars, a liquid oxygen tank car, and a liquid hydrogen dewar or tank car will be transferred for delivery to the SpaceX engine test complex outside McGregor, Texas. The railroad cars were needed in support of the Space Shuttle Program but currently are not in use by NASA following the completion of the program in 2011. Originally, the tankers belonged to the U.S. Bureau of Mines. At the peak of the shuttle program, there were approximately 30 cars in the fleet. About half the cars were returned to the bureau as launch activity diminished. Five tank cars are being loaned to SpaceX and repurposed to support their engine tests in Texas. Eight cars previously were shipped to California on loan to support the SpaceX Falcon 9 rocket launches from Space Launch Complex-4 on Vandenberg Air Force Base. SpaceX already has three helium tank cars previously used for the shuttle program at Space Launch Complex-40 on Cape Canaveral Air Force Station in Florida. For more information, visit http://www.nasa.gov/spacex. Photo credit: NASA/Jim Grossmann

KSC-2012-3039a

NASA Image and Video Library

2012-05-23

CAPE CANAVERAL, Fla. – A NASA Railroad train passes in front of the 525-foot-tall Vehicle Assembly Building at NASA’s Kennedy Space Center in Florida. At the far right is the Orbiter Processing Facility. The train is on its way to the Florida East Coast Railway interchange in Titusville, Fla., where the train’s helium tank cars, a liquid oxygen tank car, and a liquid hydrogen dewar or tank car will be transferred for delivery to the SpaceX engine test complex outside McGregor, Texas. The railroad cars were needed in support of the Space Shuttle Program but currently are not in use by NASA following the completion of the program in 2011. Originally, the tankers belonged to the U.S. Bureau of Mines. At the peak of the shuttle program, there were approximately 30 cars in the fleet. About half the cars were returned to the bureau as launch activity diminished. Five tank cars are being loaned to SpaceX and repurposed to support their engine tests in Texas. Eight cars previously were shipped to California on loan to support the SpaceX Falcon 9 rocket launches from Space Launch Complex-4 on Vandenberg Air Force Base. SpaceX already has three helium tank cars previously used for the shuttle program at Space Launch Complex-40 on Cape Canaveral Air Force Station in Florida. For more information, visit http://www.nasa.gov/spacex. Photo credit: NASA/Jim Grossmann

KSC-2012-3036a

NASA Image and Video Library

2012-05-23

CAPE CANAVERAL, Fla. – A NASA Railroad train passes in front of the twin bays of the Orbiter Processing Facility at NASA’s Kennedy Space Center in Florida. The train is on its way to the Florida East Coast Railway interchange in Titusville, Fla., where the train’s helium tank cars, a liquid oxygen tank car, and a liquid hydrogen dewar or tank car will be transferred for delivery to the SpaceX engine test complex outside McGregor, Texas. The railroad cars were needed in support of the Space Shuttle Program but currently are not in use by NASA following the completion of the program in 2011. Originally, the tankers belonged to the U.S. Bureau of Mines. At the peak of the shuttle program, there were approximately 30 cars in the fleet. About half the cars were returned to the bureau as launch activity diminished. Five tank cars are being loaned to SpaceX and repurposed to support their engine tests in Texas. Eight cars previously were shipped to California on loan to support the SpaceX Falcon 9 rocket launches from Space Launch Complex-4 on Vandenberg Air Force Base. SpaceX already has three helium tank cars previously used for the shuttle program at Space Launch Complex-40 on Cape Canaveral Air Force Station in Florida. For more information, visit http://www.nasa.gov/spacex. Photo credit: NASA/Jim Grossmann

KSC-2012-3035a

NASA Image and Video Library

2012-05-23

CAPE CANAVERAL, Fla. – A NASA Railroad train passes in front of the twin bays of the Orbiter Processing Facility at NASA’s Kennedy Space Center in Florida. The train is on its way to the Florida East Coast Railway interchange in Titusville, Fla., where the train’s helium tank cars, a liquid oxygen tank car, and a liquid hydrogen dewar or tank car will be transferred for delivery to the SpaceX engine test complex outside McGregor, Texas. The railroad cars were needed in support of the Space Shuttle Program but currently are not in use by NASA following the completion of the program in 2011. Originally, the tankers belonged to the U.S. Bureau of Mines. At the peak of the shuttle program, there were approximately 30 cars in the fleet. About half the cars were returned to the bureau as launch activity diminished. Five tank cars are being loaned to SpaceX and repurposed to support their engine tests in Texas. Eight cars previously were shipped to California on loan to support the SpaceX Falcon 9 rocket launches from Space Launch Complex-4 on Vandenberg Air Force Base. SpaceX already has three helium tank cars previously used for the shuttle program at Space Launch Complex-40 on Cape Canaveral Air Force Station in Florida. For more information, visit http://www.nasa.gov/spacex. Photo credit: NASA/Jim Grossmann

Automatic differential analysis of NMR experiments in complex samples.

PubMed

Margueritte, Laure; Markov, Petar; Chiron, Lionel; Starck, Jean-Philippe; Vonthron-Sénécheau, Catherine; Bourjot, Mélanie; Delsuc, Marc-André

2018-06-01

Liquid state nuclear magnetic resonance (NMR) is a powerful tool for the analysis of complex mixtures of unknown molecules. This capacity has been used in many analytical approaches: metabolomics, identification of active compounds in natural extracts, and characterization of species, and such studies require the acquisition of many diverse NMR measurements on series of samples. Although acquisition can easily be performed automatically, the number of NMR experiments involved in these studies increases very rapidly, and this data avalanche requires to resort to automatic processing and analysis. We present here a program that allows the autonomous, unsupervised processing of a large corpus of 1D, 2D, and diffusion-ordered spectroscopy experiments from a series of samples acquired in different conditions. The program provides all the signal processing steps, as well as peak-picking and bucketing of 1D and 2D spectra, the program and its components are fully available. In an experiment mimicking the search of a bioactive species in a natural extract, we use it for the automatic detection of small amounts of artemisinin added to a series of plant extracts and for the generation of the spectral fingerprint of this molecule. This program called Plasmodesma is a novel tool that should be useful to decipher complex mixtures, particularly in the discovery of biologically active natural products from plants extracts but can also in drug discovery or metabolomics studies. Copyright © 2017 John Wiley & Sons, Ltd.

Archive data base and handling system for the Orbiter flying qualities experiment program

NASA Technical Reports Server (NTRS)

Myers, T. T.; Dimarco, R.; Magdaleno, R. E.; Aponso, B. L.

1986-01-01

The OFQ archives data base and handling system assembled as part of the Orbiter Flying Qualities (OFQ) research of the Orbiter Experiments Program (EOX) are described. The purpose of the OFQ archives is to preserve and document shuttle flight data relevant to vehicle dynamics, flight control, and flying qualities in a form that permits maximum use for qualified users. In their complete form, the OFQ archives contain descriptive text (general information about the flight, signal descriptions and units) as well as numerical time history data. Since the shuttle program is so complex, the official data base contains thousands of signals and very complex entries are required to obtain data. The OFQ archives are intended to provide flight phase oriented data subsets with relevant signals which are easily identified for flying qualities research.

C++, objected-oriented programming, and astronomical data models

NASA Technical Reports Server (NTRS)

Farris, A.

1992-01-01

Contemporary astronomy is characterized by increasingly complex instruments and observational techniques, higher data collection rates, and large data archives, placing severe stress on software analysis systems. The object-oriented paradigm represents a significant new approach to software design and implementation that holds great promise for dealing with this increased complexity. The basic concepts of this approach will be characterized in contrast to more traditional procedure-oriented approaches. The fundamental features of objected-oriented programming will be discussed from a C++ programming language perspective, using examples familiar to astronomers. This discussion will focus on objects, classes and their relevance to the data type system; the principle of information hiding; and the use of inheritance to implement generalization/specialization relationships. Drawing on the object-oriented approach, features of a new database model to support astronomical data analysis will be presented.

The program complex for vocal recognition

NASA Astrophysics Data System (ADS)

Konev, Anton; Kostyuchenko, Evgeny; Yakimuk, Alexey

2017-01-01

This article discusses the possibility of applying the algorithm of determining the pitch frequency for the note recognition problems. Preliminary study of programs-analogues were carried out for programs with function “recognition of the music”. The software package based on the algorithm for pitch frequency calculation was implemented and tested. It was shown that the algorithm allows recognizing the notes in the vocal performance of the user. A single musical instrument, a set of musical instruments, and a human voice humming a tune can be the sound source. The input file is initially presented in the .wav format or is recorded in this format from a microphone. Processing is performed by sequentially determining the pitch frequency and conversion of its values to the note. According to test results, modification of algorithms used in the complex was planned.

Development of an Inter-Service Complex Wound and Limb Salvage Center within the DoD (Briefing charts)

DTIC Science & Technology

2010-10-15

CWLSC Patient Growth: 2008-2010  Complex soft-tissue wound management in austere settings  NPWT/VAC application and management  Ostomy , fistula, and...acute and chronic wounds Complex Wound Limb Salvage Program WRAMC/NNMC Inpatient Care Wound and Ostomy NNMC and WRAMC Outpatient Care 2 Clinics...Standardization Ostomy Wound care Skin Care Cleansers Research / EBP Pressure ulcer protocol CPG development Wound education research grant WRNMMC

Environmental Assessment (EA): Proposed Emergency Power Unit Overhaul Complex at Little Mountain Test Annex, Utah

DTIC Science & Technology

2014-03-14

NUMBER FA8201-09-D-0002 Overhaul Complex at Little Mountain Test Annex, Utah 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S...AND ADDRESS(ES) 8. PERFORMING ORGANIZATION REPORT NUMBER Streamline Consulting, LLC 1713 N. Sweetwater Lane Farmington, Utah 84025...Hill Air Force Base (AFB) proposes to construct a new emergency power unit overhaul complex at Little Mountain Test Annex, Utah . Buildings 2005

Atmospheric Radiation Measurement Program facilities newsletter, March 2000

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sisterson, D. L.

2000-04-03

The Atmospheric Radiation Measurement Program (ARM Program) is sending a copy of the ARM Video, an education overview of their program. In the video you will see and hear ARM scientists describe the importance of studying climate and climate change. It also contains a tour of some ARM sites and a look at state-of-the-art meteorological instrumentation, along with background information about the radiation budget and the complexity of climate modeling. The video was produced by the US Department of Energy.

Boiler plant training

DOE Office of Scientific and Technical Information (OSTI.GOV)

Peffley, R.E.

Developing an operator training program depends on each individual power plant's operating characteristics. This paper deals with the development of the existing, workable program used at the Eckert and Erickson Stations - Board of Water and Light, Lansing, Michigan. The Eckert Station is a coal fired complex consisting of 3 to 45 MW, 3 to 80 MW, and 4 process steam boilers. This training program encompasses seven (7) operating classifications administered by a Head Operator. A similar program is employed at a single unit 160 MW Erickson Station, covering three (3) operating classifications.

Information Technology Innovation in the U.S. Army: The Case of the Adoption, Adaptation, and Utilization of the Strategic Crisis Exercise Intranet.

DTIC Science & Technology

1999-01-01

the system using widely available Microsoft Visual and Access Basic programming language . For SCE 󈨦, SWAMI was upgraded to automatically update...into pseudo-code and pass it on to contractors to program, usually using a complex programming language like FORTRAN. Army operations research...easier to use than programming languages like FORTRAN or C, there was still very little expertise in HTML among the instructors and controllers who were

[Complex program for the recovery of the vertebral column motor function].

PubMed

Kukareko, V P; Furmanov, A G

2011-01-01

This paper addresses the problems pertinent to the improvement of the efficacy of restoration of the vertebral column motor function based on the implementation of a comprehensive therapeutic program including massage, thermal procedures, and physical exercises. The program was realized in three phases, viz. preparatory, basic, and consolidating. The results of integral estimation of the whole body and vertebral column condition were taken into consideration. The experiment lasted 6 months and confirmed high efficiency of the comprehensive program.

Using a graphical programming language to write CAMAC/GPIB instrument drivers

NASA Technical Reports Server (NTRS)

Zambrana, Horacio; Johanson, William

1991-01-01

To reduce the complexities of conventional programming, graphical software was used in the development of instrumentation drivers. The graphical software provides a standard set of tools (graphical subroutines) which are sufficient to program the most sophisticated CAMAC/GPIB drivers. These tools were used and instrumentation drivers were successfully developed for operating CAMAC/GPIB hardware from two different manufacturers: LeCroy and DSP. The use of these tools is presented for programming a LeCroy A/D Waveform Analyzer.

University Research Consortium annual review meeting program

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1996-07-01

This brochure presents the program for the first annual review meeting of the University Research Consortium (URC) of the Idaho National Engineering Laboratory (INEL). INEL is a multiprogram laboratory with a distinctive role in applied engineering. It also conducts basic science research and development, and complex facility operations. The URC program consists of a portfolio of research projects funded by INEL and conducted at universities in the United States. In this program, summaries and participant lists for each project are presented as received from the principal investigators.

A Practical School Public Relations Research Primer

ERIC Educational Resources Information Center

Moore, Edward H.

2010-01-01

Advances in communication technology have created many new tools for school communicators--as well as increasing complexities for their programs. As a result, solid school communication research programs offering practical research insights for planning, tracking, and assessing school communication efforts are more important than ever. Still, many…

Organizational Structures that Support Internal Program Evaluation

ERIC Educational Resources Information Center

Lambur, Michael T.

2008-01-01

This chapter explores how the structure of large complex organizations such as Cooperative Extension affects their ability to support internal evaluation of their programs and activities. Following a literature review of organizational structure and its relation to internal evaluation capacity, the chapter presents the results of interviews with…

The Social Benefits of Intramural Sports

ERIC Educational Resources Information Center

Artinger, Lori; Clapham, Lisa; Hunt, Carla; Meigs, Matthew; Milord, Nadia; Sampson, Bryan; Forrester, Scott A.

2006-01-01

One of the distinguishing features of collegiate student recreational sports complexes is the sense of community that is intentionally introduced in the programs and services that occur within these facilities. Intramural sports programs provide a powerful medium for student interaction (Belch, Gebel, & Mass, 2001). This study was designed to…

Professional Identity Formation: Considerations for Athletic Training Education

ERIC Educational Resources Information Center

Peer, Kimberly S.

2016-01-01

Clinical education is a complex element of educational programs in health care. Understanding identity is important because how educators structure learning experiences and foster the development of professionals within these programs impacts students as they emerge into professional practice. This article discusses five cultural dimensions of…

Introduction to the Application of the Dynalist Computer Program to the Analysis of Rail Systems Dynamics

DOT National Transportation Integrated Search

1974-08-01

DYNALIST, a computer program that extracts complex eigenvalues and eigenvectors for dynamic systems described in terms of matrix equations of motion, has been acquired and made operational at TSC. In this report, simple dynamic systems are used to de...

Understanding the Organizational Context of Academic Program Development

ERIC Educational Resources Information Center

Dee, Jay R.; Heineman, William A.

2016-01-01

This chapter provides a conceptual model that academic leaders can use to navigate the complex, and often contentious, organizational terrain of academic program development. The model includes concepts related to the institution's external environment, as well as internal organizational structures, cultures, and politics. Drawing from the…

41 CFR 101-5.305 - Agency participation.

Code of Federal Regulations, 2012 CFR

2012-07-01

... Regulations System FEDERAL PROPERTY MANAGEMENT REGULATIONS GENERAL 5-CENTRALIZED SERVICES IN FEDERAL BUILDINGS AND COMPLEXES 5.3-Federal Employee Health Services § 101-5.305 Agency participation. At the time the... occupational health services program. Each agency desiring to participate in the program will be requested to...

41 CFR 101-5.305 - Agency participation.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Regulations System FEDERAL PROPERTY MANAGEMENT REGULATIONS GENERAL 5-CENTRALIZED SERVICES IN FEDERAL BUILDINGS AND COMPLEXES 5.3-Federal Employee Health Services § 101-5.305 Agency participation. At the time the... occupational health services program. Each agency desiring to participate in the program will be requested to...

41 CFR 101-5.305 - Agency participation.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Regulations System FEDERAL PROPERTY MANAGEMENT REGULATIONS GENERAL 5-CENTRALIZED SERVICES IN FEDERAL BUILDINGS AND COMPLEXES 5.3-Federal Employee Health Services § 101-5.305 Agency participation. At the time the... occupational health services program. Each agency desiring to participate in the program will be requested to...

41 CFR 101-5.305 - Agency participation.

Code of Federal Regulations, 2014 CFR

2014-07-01

... Regulations System FEDERAL PROPERTY MANAGEMENT REGULATIONS GENERAL 5-CENTRALIZED SERVICES IN FEDERAL BUILDINGS AND COMPLEXES 5.3-Federal Employee Health Services § 101-5.305 Agency participation. At the time the... occupational health services program. Each agency desiring to participate in the program will be requested to...

The Electronic Guinea Pig.

ERIC Educational Resources Information Center

Angier, Natalie

1983-01-01

Scientists are designing computer models of biological systems, and of compounds with complex molecules, that can be used to get answers once obtainable only by sacrificing laboratory animals. Although most programs are still under development, some are in use by industrial/pharmaceutical companies. The programs and experiments they simulate are…

Qualitative and Quantitative Methods for Developing a Typology of Community Engagement with Sustainability Programs

EPA Science Inventory

Identifying the needs that a community must satisfy to implement sustainability programs is complex, with interplay between geographic, environmental and social influences. Helping communities meet these needs is a focus of the U.S. Environmental Protection Agency’s (U.S. E...

Financing newborn screening: sources, issues, and future considerations.

PubMed

Therrell, Bradford L; Williams, Donna; Johnson, Kay; Lloyd-Puryear, Michele A; Mann, Marie Y; Ramos, Lauren Raskin

2007-01-01

Newborn screening (NBS) programs are population-based public health programs and are uniquely financed footline compared with many other public health programs. Since they began more than 45 years ago, the financing issues have become more complex for NBS programs. Today, almost all programs have a portion of their costs paid by fees. The fee amounts vary from program to program, with little standardization in the way they are formulated, collected, or used. We previously surveyed 37 of the 51 dried blood spot screening programs throughout the United States, and confirmed an increasing dependence on NBS fees. In this study, we have collected responses from all 51 programs (100%), including updated responses from the original 37, and updated our fee listings. Comments from those surveyed indicated that the lack of a national standardized procedural coding system for NBS contributes to billing complexities. We suggest one coding possibility for discussion and debate for such a system. Differences in Medicaid interpretations may also contribute to financing inequities across NBS programs and there may be benefit from certain clarifications at the national level. Completed survey responses accounted for few changes in the conclusions of our original survey. We confirmed that 90 percent of all NBS programs have a fee paid by parents or a third party payer. Sixty-one percent reported receiving some funds from the Maternal and Child Health Services Title V block grant, 33 percent reported some funding from state general revenue/general public health appropriations; and 24 percent reported obtaining direct reimbursement from Medicaid (without passing through a third party). A majority of programs (63%) reported budget increases between 2002 and 2005, with increases primarily from fees (72%) and to a lesser extent from Medicaid, the Title V block grant, and state general revenues.

SIMPSON: A General Simulation Program for Solid-State NMR Spectroscopy

NASA Astrophysics Data System (ADS)

Bak, Mads; Rasmussen, Jimmy T.; Nielsen, Niels Chr.

2000-12-01

A computer program for fast and accurate numerical simulation of solid-state NMR experiments is described. The program is designed to emulate a NMR spectrometer by letting the user specify high-level NMR concepts such as spin systems, nuclear spin interactions, RF irradiation, free precession, phase cycling, coherence-order filtering, and implicit/explicit acquisition. These elements are implemented using the Tcl scripting language to ensure a minimum of programming overhead and direct interpretation without the need for compilation, while maintaining the flexibility of a full-featured programming language. Basicly, there are no intrinsic limitations to the number of spins, types of interactions, sample conditions (static or spinning, powders, uniaxially oriented molecules, single crystals, or solutions), and the complexity or number of spectral dimensions for the pulse sequence. The applicability ranges from simple 1D experiments to advanced multiple-pulse and multiple-dimensional experiments, series of simulations, parameter scans, complex data manipulation/visualization, and iterative fitting of simulated to experimental spectra. A major effort has been devoted to optimizing the computation speed using state-of-the-art algorithms for the time-consuming parts of the calculations implemented in the core of the program using the C programming language. Modification and maintenance of the program are facilitated by releasing the program as open source software (General Public License) currently at http://nmr.imsb.au.dk. The general features of the program are demonstrated by numerical simulations of various aspects for REDOR, rotational resonance, DRAMA, DRAWS, HORROR, C7, TEDOR, POST-C7, CW decoupling, TPPM, F-SLG, SLF, SEMA-CP, PISEMA, RFDR, QCPMG-MAS, and MQ-MAS experiments.

SIMPSON: A general simulation program for solid-state NMR spectroscopy

NASA Astrophysics Data System (ADS)

Bak, Mads; Rasmussen, Jimmy T.; Nielsen, Niels Chr.

2011-12-01

A computer program for fast and accurate numerical simulation of solid-state NMR experiments is described. The program is designed to emulate a NMR spectrometer by letting the user specify high-level NMR concepts such as spin systems, nuclear spin interactions, RF irradiation, free precession, phase cycling, coherence-order filtering, and implicit/explicit acquisition. These elements are implemented using the Tel scripting language to ensure a minimum of programming overhead and direct interpretation without the need for compilation, while maintaining the flexibility of a full-featured programming language. Basicly, there are no intrinsic limitations to the number of spins, types of interactions, sample conditions (static or spinning, powders, uniaxially oriented molecules, single crystals, or solutions), and the complexity or number of spectral dimensions for the pulse sequence. The applicability ranges from simple ID experiments to advanced multiple-pulse and multiple-dimensional experiments, series of simulations, parameter scans, complex data manipulation/visualization, and iterative fitting of simulated to experimental spectra. A major effort has been devoted to optimizing the computation speed using state-of-the-art algorithms for the time-consuming parts of the calculations implemented in the core of the program using the C programming language. Modification and maintenance of the program are facilitated by releasing the program as open source software (General Public License) currently at http://nmr.imsb.au.dk. The general features of the program are demonstrated by numerical simulations of various aspects for REDOR, rotational resonance, DRAMA, DRAWS, HORROR, C7, TEDOR, POST-C7, CW decoupling, TPPM, F-SLG, SLF, SEMA-CP, PISEMA, RFDR, QCPMG-MAS, and MQ-MAS experiments.

A constraint logic programming approach to associate 1D and 3D structural components for large protein complexes.

PubMed

Dal Palù, Alessandro; Pontelli, Enrico; He, Jing; Lu, Yonggang

2007-01-01

The paper describes a novel framework, constructed using Constraint Logic Programming (CLP) and parallelism, to determine the association between parts of the primary sequence of a protein and alpha-helices extracted from 3D low-resolution descriptions of large protein complexes. The association is determined by extracting constraints from the 3D information, regarding length, relative position and connectivity of helices, and solving these constraints with the guidance of a secondary structure prediction algorithm. Parallelism is employed to enhance performance on large proteins. The framework provides a fast, inexpensive alternative to determine the exact tertiary structure of unknown proteins.

Users manual for program ADMIT: Admittance and pressure transfer function developed for use on a PC computer

NASA Technical Reports Server (NTRS)

Armstrong, Wilbur C.

1992-01-01

The piping in a liquid rocket can assume complex configurations due to multiple tanks, multiple engines, and structures that must be piped around. The capability to handle some of these complex configurations have been incorporated into the ADMIT code. The capability to modify the input on line has been implemented. The configurations allowed include multiple tanks, multiple engines, the splitting of a pipe into unequal segments going to different (or the same) engines. This program will handle the following type elements: straight pipes, bends, inline accumulators, tuned stub accumulators, Helmholtz resonators, parallel resonators, pumps, split pipes, multiple tanks, and multiple engines.

A Review of Hypersonics Aerodynamics, Aerothermodynamics and Plasmadynamics Activities within NASA's Fundamental Aeronautics Program

NASA Technical Reports Server (NTRS)

Salas, Manuel D.

2007-01-01

The research program of the aerodynamics, aerothermodynamics and plasmadynamics discipline of NASA's Hypersonic Project is reviewed. Details are provided for each of its three components: 1) development of physics-based models of non-equilibrium chemistry, surface catalytic effects, turbulence, transition and radiation; 2) development of advanced simulation tools to enable increased spatial and time accuracy, increased geometrical complexity, grid adaptation, increased physical-processes complexity, uncertainty quantification and error control; and 3) establishment of experimental databases from ground and flight experiments to develop better understanding of high-speed flows and to provide data to validate and guide the development of simulation tools.

Teaching physics to radiology residents.

PubMed

Hendee, William R

2009-04-01

The complexity of diagnostic imaging has expanded dramatically over the past two decades. Over the same period, the time and effort devoted to teaching physics (the science and technology of the discipline) have diminished. This paradox compromises the ability of future radiologists to master imaging technologies so that they are used in an efficient, safe, and cost-effective manner. This article addresses these issues. Efforts involving many professional organizations are under way to resolve the paradox of the expanding complexity of medical imaging contrasted with the declining emphasis on physics in radiology residency programs. These efforts should help to reestablish physics education as a core value in radiology residency programs.

Users manual for program SSFREQ intermediate mode stability curves: Developed for use on a PC computer

NASA Technical Reports Server (NTRS)

Armstrong, Wilbur C.

1992-01-01

The piping in a liquid rocket can assume complex configurations due to multiple tanks, multiple engines, and structures that must be piped around. The capability to handle some of these complex configurations have been incorporated into the SSFREQ code. The capability to modify the input on line has been implemented. The configurations allowed include multiple tanks, multiple engines, the splitting of a pipe into equal segments going to different (or the same) engines. This program will handle the following type elements: straight pipes, bends, inline accumulators, tuned stub accumulators, Helmholtz resonators, parallel resonators, pumps, split pipes, multiple tanks, and multiple engines.

Defining protein electrostatic recognition processes

NASA Astrophysics Data System (ADS)

Getzoff, Elizabeth D.; Roberts, Victoria A.

The objective is to elucidate the nature of electrostatic forces controlling protein recognition processes by using a tightly coupled computational and interactive computer graphics approach. The TURNIP program was developed to determine the most favorable precollision orientations for two molecules by systematic search of all orientations and evaluation of the resulting electrostatic interactions. TURNIP was applied to the transient interaction between two electron transfer metalloproteins, plastocyanin and cytochrome c. The results suggest that the productive electron-transfer complex involves interaction of the positive region of cytochrome c with the negative patch of plastocyanin, consistent with experimental data. Application of TURNIP to the formation of the stable complex between the HyHEL-5 antibody and its protein antigen lysozyme showed that long-distance electrostatic forces guide lysozyme toward the HyHEL-5 binding site, but do not fine tune its orientation. Determination of docked antigen/antibody complexes requires including steric as well as electrostatic interactions, as was done for the U10 mutant of the anti-phosphorylcholine antibody S107. The graphics program Flex, a convenient desktop workstation program for visualizing molecular dynamics and normal mode motions, was enhanced. Flex now has a user interface and was rewritten to use standard graphics libraries, so as to run on most desktop workstations.

Implementation of a Transdisciplinary Team for the Transition Support of Medically and Socially Complex Youth.

PubMed

Ciccarelli, Mary R; Gladstone, Erin B; Armstrong Richardson, Eprise A J

2015-01-01

This article reports the ongoing work of a statewide transition support program which serves youth ages 11 to 22 with medically complex conditions and socially complex lives. Seven years of transition support services have led to program evolution demonstrated via a descriptive summary of the patients along with both families' and primary care providers' responses to satisfaction surveys. An illustrative case is used to highlight the types of expertise needed in specialized transition service delivery for patients with significant complexity. The team's analysis of their transdisciplinary work processes further explains the work. Nearly three hundred youth with complex needs are served yearly. Families and primary care providers express high satisfaction with the support of the services. The case example shows the broad array of transition-specific services engaged beyond the usual skill set of pediatric or adult care coordination teams. Transdisciplinary team uses skills in collaboration, support, learning, and compromise within a trusting and respectful environment. They describe the shared responsibility and continuous learning of the whole team. Youth with complex medical conditions and complex social situations are at higher risk for problems during transition. Serving this population with a transdisciplinary model is time consuming and requires advanced expertise but, with those investments, we can meet the expectations of the youth, their families and primary care providers. Successful transdisciplinary teamwork requires sustained and focused investment. Further work is needed to describe the complexity of this service delivery along with distinct transition outcomes and costs comparisons. Copyright © 2015 Elsevier Inc. All rights reserved.

Self assembly of rectangular shapes on concentration programming and probabilistic tile assembly models

PubMed Central

Rajasekaran, Sanguthevar

2013-01-01

Efficient tile sets for self assembling rectilinear shapes is of critical importance in algorithmic self assembly. A lower bound on the tile complexity of any deterministic self assembly system for an n × n square is Ω(log(n)log(log(n))) (inferred from the Kolmogrov complexity). Deterministic self assembly systems with an optimal tile complexity have been designed for squares and related shapes in the past. However designing Θ(log(n)log(log(n))) unique tiles specific to a shape is still an intensive task in the laboratory. On the other hand copies of a tile can be made rapidly using PCR (polymerase chain reaction) experiments. This led to the study of self assembly on tile concentration programming models. We present two major results in this paper on the concentration programming model. First we show how to self assemble rectangles with a fixed aspect ratio (α:β), with high probability, using Θ(α + β) tiles. This result is much stronger than the existing results by Kao et al. (Randomized self-assembly for approximate shapes, LNCS, vol 5125. Springer, Heidelberg, 2008) and Doty (Randomized self-assembly for exact shapes. In: proceedings of the 50th annual IEEE symposium on foundations of computer science (FOCS), IEEE, Atlanta. pp 85–94, 2009)—which can only self assembly squares and rely on tiles which perform binary arithmetic. On the other hand, our result is based on a technique called staircase sampling. This technique eliminates the need for sub-tiles which perform binary arithmetic, reduces the constant in the asymptotic bound, and eliminates the need for approximate frames (Kao et al. Randomized self-assembly for approximate shapes, LNCS, vol 5125. Springer, Heidelberg, 2008). Our second result applies staircase sampling on the equimolar concentration programming model (The tile complexity of linear assemblies. In: proceedings of the 36th international colloquium automata, languages and programming: Part I on ICALP ’09, Springer-Verlag, pp 235–253, 2009), to self assemble rectangles (of fixed aspect ratio) with high probability. The tile complexity of our algorithm is Θ(log(n)) and is optimal on the probabilistic tile assembly model (PTAM)—n being an upper bound on the dimensions of a rectangle. PMID:24311993

The theory of interface slicing

NASA Technical Reports Server (NTRS)

Beck, Jon

1993-01-01

Interface slicing is a new tool which was developed to facilitate reuse-based software engineering, by addressing the following problems, needs, and issues: (1) size of systems incorporating reused modules; (2) knowledge requirements for program modification; (3) program understanding for reverse engineering; (4) module granularity and domain management; and (5) time and space complexity of conventional slicing. The definition of a form of static program analysis called interface slicing is addressed.

Analysis of structural dynamic data from Skylab. Volume 1: Technical discussion

NASA Technical Reports Server (NTRS)

Demchak, L.; Harcrow, H.

1976-01-01

A compendium of Skylab structural dynamics analytical and test programs is presented. These programs are assessed to identify lessons learned from the structural dynamic prediction effort and to provide guidelines for future analysts and program managers of complex spacecraft systems. It is a synopsis of the structural dynamic effort performed under the Skylab Integration contract and specifically covers the development, utilization, and correlation of Skylab Dynamic Orbital Models.

Root Cause Analyses of Nunn-McCurdy Breaches. Volume 2: Excalibur Artillery Projectile and the Navy Enterprise Resource Planning Program, with an Approach to Analyzing Program Complexity and Risk

DTIC Science & Technology

2012-01-01

The mismatch, it was feared, would wreck the processes that the ERP was trying to improve; customers did not have the choice of putting the ERP...program features ahead of attempting a deep dive into the data looking for problems. An initial conceptual framework would allow a decision- maker to

Computer program for calculation of complex chemical equilibrium compositions and applications. Supplement 1: Transport properties

NASA Technical Reports Server (NTRS)

Gordon, S.; Mcbride, B.; Zeleznik, F. J.

1984-01-01

An addition to the computer program of NASA SP-273 is given that permits transport property calculations for the gaseous phase. Approximate mixture formulas are used to obtain viscosity and frozen thermal conductivity. Reaction thermal conductivity is obtained by the same method as in NASA TN D-7056. Transport properties for 154 gaseous species were selected for use with the program.

International space station wire program

NASA Technical Reports Server (NTRS)

May, Todd

1995-01-01

Hardware provider wire systems and current wire insulation issues for the International Space Station (ISS) program are discussed in this viewgraph presentation. Wire insulation issues include silicone wire contamination, Tefzel cold temperature flexibility, and Russian polyimide wire insulation. ISS is a complex program with hardware developed and managed by many countries and hundreds of contractors. Most of the obvious wire insulation issues are known by contractors and have been precluded by proper selection.

Suicide and the 'Poison Complex': Toxic Relationalities, Child Development, and the Sri Lankan Self-Harm Epidemic.

PubMed

Widger, Tom

2015-01-01

Suicide prevention efforts in Asia have increasingly turned to 'quick win' means restriction, while more complicated cognitive restriction and psychosocial programs are limited. This article argues the development of cognitive restriction programs requires greater consideration of suicide methods as social practices, and of how suicide cognitive schemata form. To illustrate this, the article contributes an ethnographically grounded study of how self-poisoning becomes cognitively available in Sri Lanka. I argue the overwhelming preference for poison as a method of self-harm in the country is not simply reflective of its widespread availability, but rather how cognitive schemata of poison-a 'poison complex'-develops from early childhood and is a precondition for suicide schemata. Limiting cognitive availability thus requires an entirely novel approach to suicide prevention that draws back from its immediate object (methods and causes of self-harm) to engage the wider poison complex of which suicide is just one aspect.

Synthetic mixed-signal computation in living cells

PubMed Central

Rubens, Jacob R.; Selvaggio, Gianluca; Lu, Timothy K.

2016-01-01

Living cells implement complex computations on the continuous environmental signals that they encounter. These computations involve both analogue- and digital-like processing of signals to give rise to complex developmental programs, context-dependent behaviours and homeostatic activities. In contrast to natural biological systems, synthetic biological systems have largely focused on either digital or analogue computation separately. Here we integrate analogue and digital computation to implement complex hybrid synthetic genetic programs in living cells. We present a framework for building comparator gene circuits to digitize analogue inputs based on different thresholds. We then demonstrate that comparators can be predictably composed together to build band-pass filters, ternary logic systems and multi-level analogue-to-digital converters. In addition, we interface these analogue-to-digital circuits with other digital gene circuits to enable concentration-dependent logic. We expect that this hybrid computational paradigm will enable new industrial, diagnostic and therapeutic applications with engineered cells. PMID:27255669

Enzyme-free nucleic acid dynamical systems.

PubMed

Srinivas, Niranjan; Parkin, James; Seelig, Georg; Winfree, Erik; Soloveichik, David

2017-12-15

Chemistries exhibiting complex dynamics-from inorganic oscillators to gene regulatory networks-have been long known but either cannot be reprogrammed at will or rely on the sophisticated enzyme chemistry underlying the central dogma. Can simpler molecular mechanisms, designed from scratch, exhibit the same range of behaviors? Abstract chemical reaction networks have been proposed as a programming language for complex dynamics, along with their systematic implementation using short synthetic DNA molecules. We developed this technology for dynamical systems by identifying critical design principles and codifying them into a compiler automating the design process. Using this approach, we built an oscillator containing only DNA components, establishing that Watson-Crick base-pairing interactions alone suffice for complex chemical dynamics and that autonomous molecular systems can be designed via molecular programming languages. Copyright © 2017 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.

Nuclear adaptor Ldb1 regulates a transcriptional program essential for the maintenance of hematopoietic stem cells.

PubMed

Li, LiQi; Jothi, Raja; Cui, Kairong; Lee, Jan Y; Cohen, Tsadok; Gorivodsky, Marat; Tzchori, Itai; Zhao, Yangu; Hayes, Sandra M; Bresnick, Emery H; Zhao, Keji; Westphal, Heiner; Love, Paul E

2011-02-01

The nuclear adaptor Ldb1 functions as a core component of multiprotein transcription complexes that regulate differentiation in diverse cell types. In the hematopoietic lineage, Ldb1 forms a complex with the non-DNA-binding adaptor Lmo2 and the transcription factors E2A, Scl and GATA-1 (or GATA-2). Here we demonstrate a critical and continuous requirement for Ldb1 in the maintenance of both fetal and adult mouse hematopoietic stem cells (HSCs). Deletion of Ldb1 in hematopoietic progenitors resulted in the downregulation of many transcripts required for HSC maintenance. Genome-wide profiling by chromatin immunoprecipitation followed by sequencing (ChIP-Seq) identified Ldb1 complex-binding sites at highly conserved regions in the promoters of genes involved in HSC maintenance. Our results identify a central role for Ldb1 in regulating the transcriptional program responsible for the maintenance of HSCs.

HERMIES-3: A step toward autonomous mobility, manipulation, and perception

NASA Technical Reports Server (NTRS)

Weisbin, C. R.; Burks, B. L.; Einstein, J. R.; Feezell, R. R.; Manges, W. W.; Thompson, D. H.

1989-01-01

HERMIES-III is an autonomous robot comprised of a seven degree-of-freedom (DOF) manipulator designed for human scale tasks, a laser range finder, a sonar array, an omni-directional wheel-driven chassis, multiple cameras, and a dual computer system containing a 16-node hypercube expandable to 128 nodes. The current experimental program involves performance of human-scale tasks (e.g., valve manipulation, use of tools), integration of a dexterous manipulator and platform motion in geometrically complex environments, and effective use of multiple cooperating robots (HERMIES-IIB and HERMIES-III). The environment in which the robots operate has been designed to include multiple valves, pipes, meters, obstacles on the floor, valves occluded from view, and multiple paths of differing navigation complexity. The ongoing research program supports the development of autonomous capability for HERMIES-IIB and III to perform complex navigation and manipulation under time constraints, while dealing with imprecise sensory information.

Promoting Conditional Use of Communication Skills for Learners With Complex Communication Needs: A Tutorial.

PubMed

Simacek, Jessica; Reichle, Joe; Byiers, Breanne J; Parker-McGowan, Quannah; Dimian, Adele F; Elmquist, Marianne

2018-05-03

Conditional use of communication skills refers to the ability of a learner to appropriately generalize and discriminate when, where, and how to communicate based on constant variation and shifts in environmental cues. We describe discrimination and generalization challenges encountered by learners with complex communication needs and ways in which these challenges are fostered through traditional communication intervention programming. We address arrangements in instruction that maximize the probability of learners acquiring the conditional use of new vocabulary and the modest instructional technology implemented when planning for generalization. We propose establishing well-discriminated and generalized use of new vocabulary items through the application of a general case instruction framework to communication intervention programming. We provide intervention methodology, including intervention steps for general case instruction, a plethora of functional examples, and graphic displays to assess and intervene to promote conditional use of communication skills for learners with complex communication needs.

Instrumentation, performance visualization, and debugging tools for multiprocessors

NASA Technical Reports Server (NTRS)

Yan, Jerry C.; Fineman, Charles E.; Hontalas, Philip J.

1991-01-01

The need for computing power has forced a migration from serial computation on a single processor to parallel processing on multiprocessor architectures. However, without effective means to monitor (and visualize) program execution, debugging, and tuning parallel programs becomes intractably difficult as program complexity increases with the number of processors. Research on performance evaluation tools for multiprocessors is being carried out at ARC. Besides investigating new techniques for instrumenting, monitoring, and presenting the state of parallel program execution in a coherent and user-friendly manner, prototypes of software tools are being incorporated into the run-time environments of various hardware testbeds to evaluate their impact on user productivity. Our current tool set, the Ames Instrumentation Systems (AIMS), incorporates features from various software systems developed in academia and industry. The execution of FORTRAN programs on the Intel iPSC/860 can be automatically instrumented and monitored. Performance data collected in this manner can be displayed graphically on workstations supporting X-Windows. We have successfully compared various parallel algorithms for computational fluid dynamics (CFD) applications in collaboration with scientists from the Numerical Aerodynamic Simulation Systems Division. By performing these comparisons, we show that performance monitors and debuggers such as AIMS are practical and can illuminate the complex dynamics that occur within parallel programs.

Choosing Psychiatry as a Career: Motivators and Deterrents at a Critical Decision-Making Juncture

PubMed Central

Wiesenfeld, Lesley; Abbey, Susan; Takahashi, Sue Glover; Abrahams, Caroline

2014-01-01

Objective To examine factors influencing the choice of psychiatry as a career between residency program application and ranking decision making. Methods: Using an online questionnaire, applicants to the largest Canadian psychiatry residency program were surveyed about the impact of various factors on their ultimate decision to enter psychiatry residency training. Results: Applicants reported that patient-related stigma was a motivator in considering psychiatry as a career, but that negative comments from colleagues, friends, and family about choosing psychiatry was a deterrent. Training program length, limited treatments, and insufficient clerkship exposure were noted as deterrents to choosing psychiatry, though future job prospects, the growing role of neuroscience, and diagnostic complexity positively influenced choosing psychiatry as a specialty. Research and elective time away opportunities were deemed relatively unimportant to ranking decisions, compared with more highly weighted factors, such as program flexibility, emphasis on psychotherapy, service– training balance, and training program location. Most applicants also reported continuing to fine tune ranking decisions between the application and ranking submission deadline. Conclusions: Stigma, exposure to psychiatry, diagnostic complexity, and an encouraging job market were highlighted as positive influences on the choice to enter psychiatry residency. Interview and information days represent opportunities for continued targeted recruitment activity for psychiatry residency programs. PMID:25161070

Genetic programs can be compressed and autonomously decompressed in live cells

NASA Astrophysics Data System (ADS)

Lapique, Nicolas; Benenson, Yaakov

2018-04-01

Fundamental computer science concepts have inspired novel information-processing molecular systems in test tubes1-13 and genetically encoded circuits in live cells14-21. Recent research has shown that digital information storage in DNA, implemented using deep sequencing and conventional software, can approach the maximum Shannon information capacity22 of two bits per nucleotide23. In nature, DNA is used to store genetic programs, but the information content of the encoding rarely approaches this maximum24. We hypothesize that the biological function of a genetic program can be preserved while reducing the length of its DNA encoding and increasing the information content per nucleotide. Here we support this hypothesis by describing an experimental procedure for compressing a genetic program and its subsequent autonomous decompression and execution in human cells. As a test-bed we choose an RNAi cell classifier circuit25 that comprises redundant DNA sequences and is therefore amenable for compression, as are many other complex gene circuits15,18,26-28. In one example, we implement a compressed encoding of a ten-gene four-input AND gate circuit using only four genetic constructs. The compression principles applied to gene circuits can enable fitting complex genetic programs into DNA delivery vehicles with limited cargo capacity, and storing compressed and biologically inert programs in vivo for on-demand activation.

KENNEDY SPACE CENTER, FLA. - At the KSC Visitor Complex, former astronaut James Lovell makes the opening remarks at the induction ceremony of four Space Shuttle astronauts into the U.S. Astronaut Hall of Fame. Being inducted are Daniel Brandenstein, Robert "Hoot" Gibson, Story Musgrave, and Sally Ride. Conceived by six of the Mercury Program astronauts, the U.S. Astronaut Hall of Fame opened in 1990 to provide a place where space travelers could be remembered for their participation and accomplishments in the U.S. space program. The four new inductees join 48 previously honored astronauts from the ranks of the Gemini, Apollo, Skylab, Apollo-Soyuz, and Space Shuttle programs.

NASA Image and Video Library

2003-06-21

KENNEDY SPACE CENTER, FLA. - At the KSC Visitor Complex, former astronaut James Lovell makes the opening remarks at the induction ceremony of four Space Shuttle astronauts into the U.S. Astronaut Hall of Fame. Being inducted are Daniel Brandenstein, Robert "Hoot" Gibson, Story Musgrave, and Sally Ride. Conceived by six of the Mercury Program astronauts, the U.S. Astronaut Hall of Fame opened in 1990 to provide a place where space travelers could be remembered for their participation and accomplishments in the U.S. space program. The four new inductees join 48 previously honored astronauts from the ranks of the Gemini, Apollo, Skylab, Apollo-Soyuz, and Space Shuttle programs.

Next Steps for Research on SACD Programs: Embracing Complexity

ERIC Educational Resources Information Center

Atkins, Marc S.; Shernoff, Elisa S.; Marinez-Lora, Ane

2009-01-01

This commentary focuses on the promises and challenges facing the Social and Character Development (SACD) consortium in evaluating the effectiveness of seven universal SACD programs designed to enhance student behavior and school climate under conditions of real world practice. In this commentary, we highlight that the opportunity costs associated…

Geropsychology Training in a Specialist Geropsychology Doctoral Program

ERIC Educational Resources Information Center

Qualls, Sara Honn; Segal, Daniel L.; Benight, Charles C.; Kenny, Michael P.

2005-01-01

The first PhD specialty program in Geropsychology that launched in fall, 2004 at CU-Colorado Springs is described. Consistent with a scientist-practitioner model, the curriculum sequence builds systematically from basic to complex knowledge and skills across the domains of scientific psychology, research methodology, general clinical,…

Teaching Beginners to Program: Some Cognitive Considerations.

ERIC Educational Resources Information Center

Rogers, Jean B.

Learning to program involves developing an understanding of two hierarchies of concepts. One hierarchy consists of data and extends from very literal data (which represents only itself) to very abstract data incorporating variable values in complex interrelationships. The other hierarchy consists of the operations performed on the data and extends…

78 FR 8535 - Medicare Program: Comprehensive End-Stage Renal Disease Care Model Announcement

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-06

... develop and test innovative health care payment and service delivery models that show promise of reducing program expenditures, while preserving or enhancing the quality of care for Medicare, Medicaid, and... disease (ESRD). This population has complex health care needs, typically with comorbid conditions and...

Fetal programming and environmental exposures: Implications for prenatal care and preterm birth

EPA Science Inventory

Fetal programming is an enormously complex process that relies on numerous environmental inputs from uterine tissue, the placenta, the maternal blood supply, and other sources. Recent evidence has made clear that the process is not based entirely on genetics, but rather on a deli...

A Scheme for Text Analysis Using Fortran.

ERIC Educational Resources Information Center

Koether, Mary E.; Coke, Esther U.

Using string-manipulation algorithms, FORTRAN computer programs were designed for analysis of written material. The programs measure length of a text and its complexity in terms of the average length of words and sentences, map the occurrences of keywords or phrases, calculate word frequency distribution and certain indicators of style. Trials of…

Increasing Understanding of Cultural Differences

ERIC Educational Resources Information Center

Creeden, Jack; Kelly-Aguirre, Eileen; Visser, Aric

2016-01-01

Many high school and university students return home from global programs and often report they have changed as a result of the experience. Global educators assume the act of participating in global education programs (such as high school study abroad) will open students' eyes to the complexities of another culture because students have been…

Scalability in Distance Education: "Can We Have Our Cake and Eat It Too?"

ERIC Educational Resources Information Center

Laws, R. Dwight; Howell, Scott L.; Lindsay, Nathan K.

2003-01-01

The decision to increase distance education enrollment hinges on the factors of pedagogical effectiveness, interactivity, audience, faculty incentives, retention, program type, and profitability. A complex interplay exists among these scalability concerns (i.e., issues related to meeting the growing enrollment demand), and any program's approach…

2010 Precision Strike Annual Review Held in Springfield, Virginia on April 20-21, 2010

DTIC Science & Technology

2010-04-21

Reaction Technology Office Fogg (Acting) Director, Rapid Fielding Wyatt PD - Riley Program Oversight Dipetto Program Guidance And Assessment TBD Director...warfighters Joint Rapid Acquisition Cell Mr Thomas P Dee Complex Systems Dr Charles W Perkins Rapid Reaction Technology Office Mr Glenn A Fogg (Acting

Building an Effective School-Based Mentoring Program

ERIC Educational Resources Information Center

Smith, Cindy Ann; Stormont, Melissa A.

2011-01-01

Many youth are at risk for failure in school due to various school, family, and community characteristics. To provide more support for youth at risk, school-based mentoring programs have become increasingly popular. However, this seemingly simple intervention is actually quite complex and must be implemented with integrity and fidelity. Although…