Sample records for program dmap technical

  1. Depleted fully monolithic CMOS pixel detectors using a column based readout architecture for the ATLAS Inner Tracker upgrade

    NASA Astrophysics Data System (ADS)

    Wang, T.; Barbero, M.; Berdalovic, I.; Bespin, C.; Bhat, S.; Breugnon, P.; Caicedo, I.; Cardella, R.; Chen, Z.; Degerli, Y.; Egidos, N.; Godiot, S.; Guilloux, F.; Hemperek, T.; Hirono, T.; Krüger, H.; Kugathasan, T.; Hügging, F.; Marin Tobon, C. A.; Moustakas, K.; Pangaud, P.; Schwemling, P.; Pernegger, H.; Pohl, D.-L.; Rozanov, A.; Rymaszewski, P.; Snoeys, W.; Wermes, N.

    2018-03-01

    Depleted monolithic active pixel sensors (DMAPS), which exploit high voltage and/or high resistivity add-ons of modern CMOS technologies to achieve substantial depletion in the sensing volume, have proven to have high radiation tolerance towards the requirements of ATLAS in the high-luminosity LHC era. DMAPS integrating fast readout architectures are currently being developed as promising candidates for the outer pixel layers of the future ATLAS Inner Tracker, which will be installed during the phase II upgrade of ATLAS around year 2025. In this work, two DMAPS prototype designs, named LF-Monopix and TJ-Monopix, are presented. LF-Monopix was fabricated in the LFoundry 150 nm CMOS technology, and TJ-Monopix has been designed in the TowerJazz 180 nm CMOS technology. Both chips employ the same readout architecture, i.e. the column drain architecture, whereas different sensor implementation concepts are pursued. The paper makes a joint description of the two prototypes, so that their technical differences and challenges can be addressed in direct comparison. First measurement results for LF-Monopix will also be shown, demonstrating for the first time a fully functional fast readout DMAPS prototype implemented in the LFoundry technology.

  2. A powerful enhancement to the DMAP alter capability

    NASA Technical Reports Server (NTRS)

    Pamidi, P. R.

    1989-01-01

    A powerful enhancement to the DMAP alter capability was developed and is available on all RPK-supported versions of COSMIC/NASTRAN. This enhancement involves the addition of two alter control cards, called INSERT and DELETE, to the Executive Control Deck. These cards allow for DMAP alters to be made by referencing DMAP statements by their module names rather than by their statement numbers in the rigid format DMAP sequence. This allows for increased user convenience and flexibility and makes alters more meaningful to the user. In addition, DMAP alter packages employing the alter control cards will be much less susceptible to future changes in rigid format DMAPs than alter packages employing the standard ALTER control cards. The usage of the cards is illustrated by examples.

  3. Depletion of mitochondrial coenzyme A and glutathione by 4-dimethylaminophenol and formation of mixed thioethers.

    PubMed

    Eckert, K G; Elbers, F R; Eyer, P

    1989-10-01

    4-Dimethylaminophenol (DMAP), an antidote in cyanide poisoning, has been shown to produce kidney lesions in rats, to damage isolated rat kidney tubules and to impair mitochondrial functions as already described for 4-aminophenol. Since DMAP upon oxidation forms bis- and tris-substituted thioethers with GSH, it was anticipated that mitochondrial toxicity of DMAP might result from CoA depletion. In a model reaction DMAP was oxidized by oxyhemoglobin in the presence of CoA and GSH resulting in formation of tris-(CoA-S-yl)-DMAP, tris-(GSH-S-yl)-DMAP and two mixed thioethers, namely, (CoA-S-yl)-bis-(GSH-S-yl)-DMAP and (GSH-S-yl)-bis-(CoA-S-yl)-DMAP. The compounds were isolated by HPLC and identified spectroscopically, by amino acid analysis and Raney-Nickel desulfuration. Rat liver mitochondria (5 mg protein/ml) incubated under state IV conditions with 20 and 50 microM DMAP were depleted of GSH and total coenzyme A with formation of GSSG and the above-mentioned thioethers which were quantified by isotope dilution techniques using [14C]-labelled DMAP and the isolated, inactive thioethers. The results confirm earlier suggestions that part of the cytotoxicity of DMAP may result from depletion of vital mitochondrial thiols, particularly CoA. Since 4-aminophenol reacts analogously, similar cytotoxic effects can be expected from compounds which on (aut)oxidation form quinoid systems capable of 1.4-addition reactions with nucleophilic thiols.

  4. Solving modal equations of motion with initial conditions using MSC/NASTRAN DMAP. Part 1: Implementing exact mode superposition

    NASA Technical Reports Server (NTRS)

    Abdallah, Ayman A.; Barnett, Alan R.; Ibrahim, Omar M.; Manella, Richard T.

    1993-01-01

    Within the MSC/NASTRAN DMAP (Direct Matrix Abstraction Program) module TRD1, solving physical (coupled) or modal (uncoupled) transient equations of motion is performed using the Newmark-Beta or mode superposition algorithms, respectively. For equations of motion with initial conditions, only the Newmark-Beta integration routine has been available in MSC/NASTRAN solution sequences for solving physical systems and in custom DMAP sequences or alters for solving modal systems. In some cases, one difficulty with using the Newmark-Beta method is that the process of selecting suitable integration time steps for obtaining acceptable results is lengthy. In addition, when very small step sizes are required, a large amount of time can be spent integrating the equations of motion. For certain aerospace applications, a significant time savings can be realized when the equations of motion are solved using an exact integration routine instead of the Newmark-Beta numerical algorithm. In order to solve modal equations of motion with initial conditions and take advantage of efficiencies gained when using uncoupled solution algorithms (like that within TRD1), an exact mode superposition method using MSC/NASTRAN DMAP has been developed and successfully implemented as an enhancement to an existing coupled loads methodology at the NASA Lewis Research Center.

  5. Solving Modal Equations of Motion with Initial Conditions Using MSC/NASTRAN DMAP. Part 2; Coupled Versus Uncoupled Integration

    NASA Technical Reports Server (NTRS)

    Barnett, Alan R.; Ibrahim, Omar M.; Abdallah, Ayman A.; Sullivan, Timothy L.

    1993-01-01

    By utilizing MSC/NASTRAN DMAP (Direct Matrix Abstraction Program) in an existing NASA Lewis Research Center coupled loads methodology, solving modal equations of motion with initial conditions is possible using either coupled (Newmark-Beta) or uncoupled (exact mode superposition) integration available within module TRD1. Both the coupled and newly developed exact mode superposition methods have been used to perform transient analyses of various space systems. However, experience has shown that in most cases, significant time savings are realized when the equations of motion are integrated using the uncoupled solver instead of the coupled solver. Through the results of a real-world engineering analysis, advantages of using the exact mode superposition methodology are illustrated.

  6. The effect of gold(I) coordination on the dual fluorescence of 4-(dimethylamino)pyridine.

    PubMed

    López-de-Luzuriaga, José M; Manso, Elena; Monge, Miguel; Olmos, M Elena; Rodríguez-Castillo, María; Sampedro, Diego

    2015-06-28

    The reactions of 4(dimethylamino)pyridine (DMAP) with the gold(I) precursors [AuR(tht)] (R = C6F5, C6Cl2F3 or C6Cl5; tht = tetrahydrothiophene) lead to complexes [AuR(DMAP)] (R = C6F5 (1), C6Cl2F3 (2) or C6Cl5 (3)). X-ray diffraction studies of the complexes reveal the presence of discrete molecules in which aurophilic contacts are absent, with π-stacking (1) or hydrogen bond (2) interactions being responsible for the supramolecular arrangements found in the solid state. All complexes display fluorescence in solution in solvents of different polarities such as toluene, chloroform or acetonitrile. In all cases the emission energy is similar to the low-energy Twisted Intramolecular Charge Transfer (TICT) emission of free DMAP. TDDFT calculations confirm that the fluorescence of complexes 1-3 arises from the ICT excited state of bonded DMAP in which a 90° distortion of the pyridine ring and -NMe2 planes is observed. Model calculations based on experimental parameters show a higher degree of polarization of DMAP upon coordination to Au(I) organometallic fragments.

  7. A DMAP Program for the Selection of Accelerometer Locations in MSC/NASTRAN

    NASA Technical Reports Server (NTRS)

    Peck, Jeff; Torres, Isaias

    2004-01-01

    A new program for selecting sensor locations has been written in the DMAP (Direct Matrix Abstraction Program) language of MSC/NASTRAN. The program implements the method of Effective Independence for selecting sensor locations, and is executed within a single NASTRAN analysis as a "rigid format alter" to the normal modes solution sequence (SOL 103). The user of the program is able to choose among various analysis options using Case Control and Bulk Data entries. Algorithms tailored for the placement of both uni-axial and tri- axial accelerometers are available, as well as several options for including the model s mass distribution into the calculations. Target modes for the Effective Independence analysis are selected from the MSC/NASTRAN ASET modes calculated by the "SOL 103" solution sequence. The initial candidate sensor set is also under user control, and is selected from the ASET degrees of freedom. Analysis results are printed to the MSCINASTRAN output file (*.f06), and may include the current candidate sensors set, and their associated Effective Independence distribution, at user specified iteration intervals. At the conclusion of the analysis, the model is reduced to the final sensor set, and frequencies and orthogonality checks are printed. Example results are given for a pre-test analysis of NASA s five-segment solid rocket booster modal test.

  8. F-element metalated dipyrrins: synthesis and characterization of a family of uranyl bis(dipyrrinate) complexes.

    PubMed

    Bolotaulo, Duer; Metta-Magaña, Alejandro; Fortier, Skye

    2017-03-07

    Using an improved, chromatography-free dipyrrin synthesis, the α,β-unsubstituted dipyrrins [RC(C 4 H 2 N) 2 H] (2) (R = tolyl (2toly l ), p-OMe-C 6 H 4 (2anis), mesityl (2mes), ferrocenyl (2Fc)) were isolated in good to excellent yields. Deprotonation of 2 with Na[N(SiMe 3 ) 2 ] gives the alkali metal salts [Na(DME) n ][RC(C 4 H 2 N) 2 ] (3) which reacts with UO 2 Cl 2 (THF) 3 to give the uranyl bis(dipyrrinates) UO 2 [RC(C 4 H 2 N) 2 ] 2 (L) (L = THF (4R-THF); DMAP (4R-DMAP)) (R = tolyl, p-OMe-C 6 H 4 , mesityl, ferrocenyl). The THF adducts, 4R-THF, are unstable in aromatic and nonpolar solvents and rapidly decompose to 2 and an intractable uranium-containing solid. On the other hand, the DMAP adducts, 4R-DMAP, are indefinitely stable in solution. The solid-state structures of 4R-THF and 4R-DMAP reveal distorted trigonal bipyramidal geometries. In the solid-state, the dipyrrinate ligands exhibit significant distortions including bowing and, in some instances, out-of-plane equatorial N-atom coordination, likely as a consequence of steric crowding and interligand repulsion. The complexes, 4R-DMAP, have been fully characterized by NMR, UV/Vis, and fluorescence spectroscopies, and their electrochemical properties have been investigated through cyclic voltammetry. The cyclic voltammograms of 4R-DMAP display several redox features but present a reversible wave at ca. -1.9 V (vs. Fc 0/+ ) attributable to a ligand centred reduction. Fluorescence measurements of all compounds reveal that only the mesityl derivatives 2mes, 3mes, and 4mes fluoresce with modest Stokes shift that ranges from ca. 30-70 nm, with 4mes displaying the greatest relative emission intensity.

  9. Boomerang-type substitution reaction: reactivity of fullerene epoxides and a halofullerenol.

    PubMed

    Jia, Zhenshan; Zhang, Xiang; Zhang, Gaihong; Huang, Shaohua; Fang, Hao; Hu, Xiangqing; Li, Yuliang; Gan, Liangbing; Zhang, Shiwei; Zhu, Daoben

    2007-02-05

    The C(s)-symmetric fullerene chlorohydrin C60(Cl)(OH)(OOtBu)4 reacts with 4-dimethylaminopyridine (DMAP) and 1,4-diazabicyclo[2.2.2]octane (DABCO) to yield two isomers with the formula C60(O)(OOtBu)4 in good yields. These isomers differ with respect to the location of the epoxy functionality. The one from DMAP is C(s) symmetric, whereas that from DABCO is C1 symmetric with the epoxy group on the central pentagon. Two different mechanisms are proposed to explain the chemoselectivity of these reactions. The reaction with DMAP involves single-electron transfer as the key step; DMAP acts as the electron donor. A combination of an oxygen-atom shift and S(N)2'' processes (boomerang substitution) are responsible for the formation of isomer with DACBO. Various related reactions support the proposed mechanisms. The structures of new fullerene derivatives were determined by spectroscopy, single-crystal X-ray analysis, and chemical correlation experiments.

  10. Genotoxicity of 2,6- and 3,5-Dimethylaniline in Cultured Mammalian Cells: The Role of Reactive Oxygen Species

    PubMed Central

    Chao, Ming-Wei; Kim, Min Young; Wogan, Gerald N.

    2012-01-01

    Several alkylanilines with structures more complex than toluidines have been associated epidemiologically with human cancer. Their mechanism of action remains largely undetermined, and there is no reported evidence that it replicates that of multicyclic aromatic amines even though the principal metabolic pathways of P450-mediated hydroxylation and phase II conjugation are very similar. As a means to elucidate their mechanisms of action, lethality and mutagenicity in the adenine phosphoribosyltransferase (aprt +/−) gene induced in several Chinese hamster ovary cell types by 2,6- and 3,5-dimethylaniline (2,6-DMA, 3,5-DMA) and their N- and ring-hydroxyl derivatives (N-OH-2,6-DMA, N-OH-3,5-DMA, 2,6-DMAP, 3,5-DMAP) were assessed. Dose-response relationships were determined in the parental AA8 cell line, its repair-deficient UV5 subclone and other repair-deficient 5P3NAT2 or -proficient 5P3NAT2R9 subclones engineered to express mouse cytochrome P4501A2 (CYP1A2) and human N-acetyltransferase (NAT2), and also in AS52 cells harboring the bacterial guanine-hypoxanthine phosphoribosyltransferase (gpt) gene. Mutations in the gpt gene of AS52 cells were characterized and found to be dominated by G:C to A:T and A:T to G:C transitions. Separately, treatment of AS52 cells with N-OH-2,6-DMA, N-OH-3,5-DMA, 2,6-DMAP, 3,5-DMAP, and 3,5-DMAP led to intracellular production of reactive oxygen species (ROS) for at least 24h after removal of the mutagens in every case. Using the comet assay, DNA strand breaks were observed in a dose-dependent manner in AS52 cells when treated with each of the four N-OH-2,6-DMA, N-OH-3,5-DMA, 2,6-DMAP, and 3,5-DMAP derivatives. Comparative evaluation of the results indicates that the principal mechanism of mutagenic action is likely to be through redox cycling of intracellularly bound aminophenol/quinone imine structures to generate ROS rather than through formation of covalent DNA adducts. PMID:22831970

  11. Bubble vector in automatic merging

    NASA Technical Reports Server (NTRS)

    Pamidi, P. R.; Butler, T. G.

    1987-01-01

    It is shown that it is within the capability of the DMAP language to build a set of vectors that can grow incrementally to be applied automatically and economically within a DMAP loop that serves to append sub-matrices that are generated within a loop to a core matrix. The method of constructing such vectors is explained.

  12. Improved omit set displacement recoveries in dynamic analysis

    NASA Technical Reports Server (NTRS)

    Allen, Tom; Cook, Greg; Walls, Bill

    1993-01-01

    Two related methods for improving the dependent (OMIT set) displacements after performing a Guyan reduction are presented. The theoretical bases for the methods are derived. The NASTRAN DMAP ALTERs used to implement the methods in a NASTRAN execution are described. Data are presented that verify the methods and the NASTRAN DMAP ALTERs.

  13. The Design and Usage of the New Data Management Features in NASTRAN

    NASA Technical Reports Server (NTRS)

    Pamidi, P. R.; Brown, W. K.

    1984-01-01

    Two new data management features are installed in the April 1984 release of NASTRAN. These two features are the Rigid Format Data Base and the READFILE capability. The Rigid Format Data Base is stored on external files in card image format and can be easily maintained and expanded by the use of standard text editors. This data base provides the user and the NASTRAN maintenance contractor with an easy means for making changes to a Rigid Format or for generating new Rigid Formats without unnecessary compilations and link editing of NASTRAN. Each Rigid Format entry in the data base contains the Direct Matrix Abstraction Program (DMAP), along with the associated restart, DMAP sequence subset and substructure control flags. The READFILE capability allows an user to reference an external secondary file from the NASTRAN primary input file and to read data from this secondary file. There is no limit to the number of external secondary files that may be referenced and read.

  14. 6-Dimethylaminopurine and cyclohexamide are mutagenic and alter reproductive performance and intrauterine development in vivo.

    PubMed

    Oliveira, R J; Mantovani, M S; Pesarini, J R; Mauro, M O; da Silva, A F; Souza, T R; Ribeiro, L R

    2015-02-02

    The compounds 6-dimethylaminopurine (6-DMAP) and cyclohexamide (CHX) are currently used to stimulate the development of embryos produced by nuclear transfer in the production of cloned mammals with a great deal success. This study investigated the effects of 6-DMAP and CHX in vivo using biological assays to evaluate reproductive performance in females, teratogenesis, and mutagenesis. The results of this study demonstrated that the activating agents of oocyte cytoplasm, 6-DMAP and CHX, altered the reproductive performance of the experimental animals, as well as increased the rate malformations. In addition to these adverse effects, the administration of these compounds in pregnant females resulted in genotoxic and mutagenic toxicity, as determined by comet and micronucleus assays carried out in peripheral blood samples, respectively. Based on these findings and that alterations in DNA are important, morpho-functional teratogenesis and diminished embryonic viability, suggesting that 6-DMAP and CHX, which are utilized during the cloning of mammals, are responsible for the fact that embryos produced by nuclear transfer show low viability after implantation in utero or after birth because of congenital malformations and/or alterations in their DNA.

  15. Three new hydrochlorothiazide cocrystals: Structural analyses and solubility studies

    NASA Astrophysics Data System (ADS)

    Ranjan, Subham; Devarapalli, Ramesh; Kundu, Sudeshna; Vangala, Venu R.; Ghosh, Animesh; Reddy, C. Malla

    2017-04-01

    Hydrochlorothiazide (HCT) is a diuretic BCS class IV drug with poor aqueous solubility and low permeability leading to poor oral absorption. The present work explores the cocrystallization technique to enhance the aqueous solubility of HCT. Three new cocrystals of HCT with water soluble coformers phenazine (PHEN), 4-dimethylaminopyridine (DMAP) and picolinamide (PICA) were prepared successfully by solution crystallization method and characterized by single crystal X-ray diffraction (SCXRD), powder X-ray diffraction (PXRD), fourier transform -infraredspectroscopy (FT-IR), differential scanning calorimetry (DSC) and thermogravimetric analysis (TGA). Structural characterization revealed that the cocrystals with PHEN, DMAP and PICA exists in P21/n, P21/c and P21/n space groups, respectively. The improved solubility of HCT-DMAP (4 fold) and HCT-PHEN (1.4 fold) cocrystals whereas decreased solubility of HCT-PICA (0.5 fold) as compared to the free drug were determined after 4 h in phosphate buffer, pH 7.4, at 25 °C by using shaking flask method. HCT-DMAP showed a significant increase in solubility than all previously reported cocrystals of HCT suggest the role of a coformer. The study demonstrates that the selection of coformer could have pronounced impact on the physicochemical properties of HCT and cocrystallization can be a promising approach to improve aqueous solubility of drugs.

  16. Stiffness-generated rigid-body mode shapes for Lanczos eigensolution with SUPORT DOF by way of a MSC/NASTRAN DMAP alter

    NASA Technical Reports Server (NTRS)

    Abdallah, Ayman A.; Barnett, Alan R.; Widrick, Timothy W.; Manella, Richard T.; Miller, Robert P.

    1994-01-01

    When using all MSC/NASTRAN eigensolution methods except Lanczos, the analyst can replace the coupled system rigid-body modes calculated within DMAP module READ with mass orthogonalized and normalized rigid-body modes generated from the system stiffness. This option is invoked by defining MSC/NASTRAN r-set degrees of freedom via the SUPORT bulk data card. The newly calculated modes are required if the rigid-body modes calculated by the eigensolver are not 'clean' due to numerical roundoffs in the solution. When performing transient structural dynamic load analysis, the numerical roundoffs can result in inaccurate rigid-body accelerations which affect steady-state responses. Unfortunately, when using the Lanczos method and defining r-set degrees of freedom, the rigid-body modes calculated within DMAP module REIGL are retained. To overcome this limitation and to allow MSC/NASTRAN to handle SUPORT degrees of freedom identically for all eigensolvers, a DMAP Alter has been written which replaces Lanczos-calculated rigid-body modes with stiffness-generated rigid-body modes. The newly generated rigid-body modes are normalized with respect to the system mass and orthogonalized using the Gram-Schmidt technique. This algorithm has been implemented as an enhancement to an existing coupled loads methodology.

  17. A numerically efficient finite element hydroelastic analysis. Volume 2: Implementation in NASTRAN, part 1

    NASA Technical Reports Server (NTRS)

    Coppolino, R. N.

    1974-01-01

    Details are presented of the implementation of the new formulation into NASTRAN including descriptions of the DMAP statements required for conversion of the program and details pertaining to problem definition and bulk data considerations. Details of the current 1/8-scale space shuttle external tank mathematical model, numerical results and analysis/test comparisons are also presented. The appendices include a description and listing of a FORTRAN program used to develop harmonic transformation bulk data (multipoint constraint statements) and sample bulk data information for a number of hydroelastic problems.

  18. Transporter targeted gatifloxacin prodrugs: Synthesis, permeability, and topical ocular delivery

    PubMed Central

    Vooturi, Sunil K.; Kadam, Rajendra S.; Kompella, Uday B.

    2013-01-01

    Purpose To design and synthesize prodrugs of gatifloxacin targeting OCT, MCT, and ATB (0, +) transporters and to identify a prodrug with enhanced delivery to the back of the eye. Method Dimethylamino-propyl, carboxy-propyl, and amino-propyl(2-methyl) derivatives of gatifloxacin (GFX), DMAP-GFX, CP-GFX, and APM-GFX, were designed and synthesized to target OCT, MCT, and ATB (0, +) transporters, respectively. LC-MS method was developed to analyze drug and prodrug levels in various studies. Solubility and Log D (pH 7.4) were measured for prodrugs and the parent drug. Permeability of the prodrugs was determined in cornea, conjunctiva, and sclera-choroidretinal pigment epitheluim (SCRPE) and compared with gatifloxacin using Ussing chamber assembly. Permeability mechanisms were elucidated by determining the transport in the presence of transporter specific inhibitors. 1-Methyl-4-phenylpyridinium iodide (MPP+), nicotinic acid sodium salt, and α-methyl-DL-tryptophan were used to inhibit OCT, MCT, and ATB (0, +) transporters, respectively. A prodrug selected based on in vitro studies was administered as an eye drop to pigmented rabbits and the delivery to various eye tissues including vitreous humor was compared with gatifloxacin dosing. Results DMAP-GFX exhibited 12.8-fold greater solubility than GFX. All prodrugs were more lipophilic, with the measured Log D (pH 7.4) values ranging from 0.05 to 1.04, when compared to GFX (Log D: -1.15). DMAP-GFX showed 1.4-, 1.8-, and 1.9-fold improvement in permeability across cornea, conjunctiva, as well as SCRPE when compared to GFX. Moreover, it exhibited reduced permeability in the presence of MPP+ (competitive inhibitor of OCT), indicating OCT-mediated transport. CP-GFX showed 1.2-, 2.3- and 2.5-fold improvement in permeability across cornea, conjunctiva and SCRPE, respectively. In the presence of nicotinic acid (competitive inhibitor of MCT), permeability of CP-GFX was reduced across conjunctiva. However, cornea and SCRPE permeability of CP-GFX was not affected by nicotinic acid. APM-GFX did not show any improvement in permeability when compared to GFX across cornea, conjunctiva, and SCRPE. Based on solubility and permeability, DMAP-GFX was selected for in vivo studies. DMAP-GFX showed 3.6- and 1.95-fold higher levels in vitreous humor and CRPE compared to that of GFX at 1 hour after topical dosing. In vivo conversion of DMAP-GFX prodrug to GFX was quantified in tissues isolated at 1 hour after dosing. Prodrug-to-parent drug ratio was 8, 70, 24, 21, 29, 13, 55, and 60 % in cornea, conjunctiva, iris-ciliary body, aqueous humor, sclera, CRPE, retina, and vitreous humor, respectively. Conclusions DMAP-GFX prodrug enhanced solubility, Log D, as well as OCT mediated delivery of gatifloxacin to the back of the eye. PMID:23003105

  19. OsO(4) in ionic liquid [Bmim]PF(6): a recyclable and reusable catalyst system for olefin dihydroxylation. remarkable effect of DMAP.

    PubMed

    Yao, Qingwei

    2002-06-27

    [reaction: see text] The combination of the ionic liquid [bmim]PF(6) and DMAP provides a most simple and practical approach to the immobilization of OsO(4) as catalyst for olefin dihydroxylation. Both the catalyst and the ionic liquid can be repeatedly recycled and reused in the dihydroxylation of a variety of olefins with only a very slight drop in catalyst activity.

  20. OpenDMAP: An open source, ontology-driven concept analysis engine, with applications to capturing knowledge regarding protein transport, protein interactions and cell-type-specific gene expression

    PubMed Central

    Hunter, Lawrence; Lu, Zhiyong; Firby, James; Baumgartner, William A; Johnson, Helen L; Ogren, Philip V; Cohen, K Bretonnel

    2008-01-01

    Background Information extraction (IE) efforts are widely acknowledged to be important in harnessing the rapid advance of biomedical knowledge, particularly in areas where important factual information is published in a diverse literature. Here we report on the design, implementation and several evaluations of OpenDMAP, an ontology-driven, integrated concept analysis system. It significantly advances the state of the art in information extraction by leveraging knowledge in ontological resources, integrating diverse text processing applications, and using an expanded pattern language that allows the mixing of syntactic and semantic elements and variable ordering. Results OpenDMAP information extraction systems were produced for extracting protein transport assertions (transport), protein-protein interaction assertions (interaction) and assertions that a gene is expressed in a cell type (expression). Evaluations were performed on each system, resulting in F-scores ranging from .26 – .72 (precision .39 – .85, recall .16 – .85). Additionally, each of these systems was run over all abstracts in MEDLINE, producing a total of 72,460 transport instances, 265,795 interaction instances and 176,153 expression instances. Conclusion OpenDMAP advances the performance standards for extracting protein-protein interaction predications from the full texts of biomedical research articles. Furthermore, this level of performance appears to generalize to other information extraction tasks, including extracting information about predicates of more than two arguments. The output of the information extraction system is always constructed from elements of an ontology, ensuring that the knowledge representation is grounded with respect to a carefully constructed model of reality. The results of these efforts can be used to increase the efficiency of manual curation efforts and to provide additional features in systems that integrate multiple sources for information extraction. The open source OpenDMAP code library is freely available at PMID:18237434

  1. JPL-ANTOPT antenna structure optimization program

    NASA Technical Reports Server (NTRS)

    Strain, D. M.

    1994-01-01

    New antenna path-length error and pointing-error structure optimization codes were recently added to the MSC/NASTRAN structural analysis computer program. Path-length and pointing errors are important measured of structure-related antenna performance. The path-length and pointing errors are treated as scalar displacements for statics loading cases. These scalar displacements can be subject to constraint during the optimization process. Path-length and pointing-error calculations supplement the other optimization and sensitivity capabilities of NASTRAN. The analysis and design functions were implemented as 'DMAP ALTERs' to the Design Optimization (SOL 200) Solution Sequence of MSC-NASTRAN, Version 67.5.

  2. Transporter targeted gatifloxacin prodrugs: synthesis, permeability, and topical ocular delivery.

    PubMed

    Vooturi, Sunil K; Kadam, Rajendra S; Kompella, Uday B

    2012-11-05

    In this work, we aim to design and synthesize prodrugs of gatifloxacin targeting organic cation transporter (OCT), monocarboxylate transporter (MCT), and ATB (0, +) transporters and to identify a prodrug with enhanced delivery to the back of the eye. Dimethylamino-propyl, carboxy-propyl, and amino-propyl(2-methyl) derivatives of gatifloxacin (GFX), DMAP-GFX, CP-GFX, and APM-GFX, were designed and synthesized to target OCT, MCT, and ATB (0, +) transporters, respectively. An LC-MS method was developed to analyze drug and prodrug levels in various studies. Solubility and log D (pH 7.4) were measured for prodrugs and the parent drug. The permeability of the prodrugs was determined in the cornea, conjunctiva, and sclera-choroid-retinal pigment epitheluim (SCRPE) and compared with gatifloxacin using an Ussing chamber assembly. Permeability mechanisms were elucidated by determining the transport in the presence of transporter specific inhibitors. 1-Methyl-4-phenylpyridinium iodide (MPP+), nicotinic acid sodium salt, and α-methyl-DL-tryptophan were used to inhibit OCT, MCT, and ATB (0, +) transporters, respectively. A prodrug selected based on in vitro studies was administered as an eye drop to pigmented rabbits, and the delivery to various eye tissues including vitreous humor was compared with gatifloxacin dosing. DMAP-GFX exhibited 12.8-fold greater solubility than GFX. All prodrugs were more lipophilic, with the measured log D (pH 7.4) values ranging from 0.05 to 1.04, when compared to GFX (log D: -1.15). DMAP-GFX showed 1.4-, 1.8-, and 1.9-fold improvement in permeability across the cornea, conjunctiva, and SCRPE when compared to GFX. Moreover, it exhibited reduced permeability in the presence of MPP+ (competitive inhibitor of OCT), indicating OCT-mediated transport. CP-GFX showed 1.2-, 2.3-, and 2.5-fold improvement in permeability across the cornea, conjunctiva, and SCRPE, respectively. In the presence of nicotinic acid (competitive inhibitor of MCT), the permeability of CP-GFX was reduced across the conjunctiva. However, the cornea and SCRPE permeability of CP-GFX was not affected by nicotinic acid. APM-GFX did not show any improvement in permeability when compared to GFX across the cornea, conjunctiva, and SCRPE. Based on solubility and permeability, DMAP-GFX was selected for in vivo studies. DMAP-GFX showed 3.6- and 1.95-fold higher levels in vitreous humor and CRPE compared to that of GFX at 1 h after topical dosing. In vivo conversion of DMAP-GFX prodrug to GFX was quantified in tissues isolated at 1 h after dosing. The parent drug-to-prodrug ratio was 8, 70, 24, 21, 29, 13, 55, and 60% in the cornea, conjunctiva, iris-ciliary body, aqueous humor, sclera, CRPE, retina, and vitreous humor, respectively. In conclusion, DMAP-GFX prodrug enhanced solubility, log D, as well as OCT mediated delivery of gatifloxacin to the back of the eye.

  3. Te(II)/Te(IV) Mediated C-N Bond Formation on 2,5-Diphenyltellurophene and a Reassignment of the Product from the Reaction of PhI(OAc)2 with 2 TMS-OTf.

    PubMed

    Aprile, Antonino; Iversen, Kalon J; Wilson, David J D; Dutton, Jason L

    2015-05-18

    We report a novel C-H to C-N bond metathesis at the 3-position of 1,2-diphenyltellurophene via oxidation of the Te(II) center to Te(IV) using the I(III) oxidant [PhI(4-DMAP)2](2+). Spontaneous reduction of a transient Te(IV) coordination compound to Te(II) generates an electrophilic equivalent of 4-DMAP that substitutes at a C-H bond at the 3-position of the tellurophene. Theoretical and synthetic reaction pathway studies confirm that a Te(IV) coordination complex with 4-DMAP is an intermediate. In the course of these pathway studies, it was also found that the identity of the I(III) oxidant generated from PhI(OAc)2 and 2 TMS-OTf is PhI(OAc)(OTf) and not PhI(OTf)2, as had been previously thought.

  4. Characterization of fatty acid amide hydrolase activity by a fluorescence-based assay.

    PubMed

    Dato, Florian M; Maaßen, Andreas; Goldfuß, Bernd; Pietsch, Markus

    2018-04-01

    Fatty acid amide hydrolase (FAAH) is involved in many human diseases, particularly cancer, pain and inflammation as well as neurological, metabolic and cardiovascular disorders. Therefore, FAAH is an attractive target for the development of low-molecular-weight inhibitors as therapeutics, which requires robust assays that can be used for high-throughput screening (HTS) of compound libraries. Here, we report the development of a fluorometric assay based on FAAH's ability to effectively hydrolyze medium-chain fatty acid amides, introducing N-decanoyl-substituted 5-amino-2-methoxypyridine (D-MAP) as new amide substrate. D-MAP is cleaved by FAAH with an 8-fold larger specificity constant than the previously reported octanoyl-analog Oc-MAP (V max /K m of 1.09 and 0.134 mL min -1 mg -1 , respectively), with both MAP derivatives possessing superior substrate properties and much increased aqueous solubility compared to the respective p-nitroaniline compounds D-pNA and Oc-pNA. The new assay with D-MAP as substrate is highly sensitive using a lower enzyme concentration (1 μg mL -1 ) than literature-reported fluorimetric FAAH assays. In addition, D-MAP was validated in comparison to the substrate Oc-MAP for the characterization of FAAH inhibitors by means of the reference compounds URB597 and TC-F2 and was shown to be highly suitable for HTS in both kinetic and endpoint assays (Z' factors of 0.81 and 0.78, respectively). Copyright © 2018 Elsevier Inc. All rights reserved.

  5. Tissue-Specific Expression of DNA Methyltransferases Involved in Early-Life Nutritional Stress of Chicken, Gallus gallus

    PubMed Central

    Kang, Seong W.; Madkour, Mahmoud; Kuenzel, Wayne J.

    2017-01-01

    DNA methylation was reported as a possible stress-adaptation mechanism involved in the transcriptional regulation of stress responsive genes. Limited data are available on effects of psychological stress and early-life nutritional stress on DNA methylation regulators [DNMTs: DNA (cytosine-5)-methyltransferase 1 (DNMT1), DNMT1 associated protein (DMAP1), DNMT 3 alpha (DNMT3A) and beta (DNMT3B)] in avian species. The objectives of this study were to: (1) investigate changes in expression of DNMT1, DMAP1, DNMT3A, and DNMT3B following acute (AS) or chronic immobilization stress (CS); (2) test immediate effect of early-life nutritional stress [food deprivation (FD) for 12 h (12hFD) or 36 h (36hFD) at the post-hatching period] on expression of DNA methylation regulators and glucocorticoid receptor (GR), and the long-term effect of early-life nutritional stress at 6 weeks of age. Expression of DNMTs and plasma corticosterone (CORT) concentration decreased by CS compared to AS (p < 0.05), indicating differential roles of DNA methylation regulators in the stress response. Plasma CORT at 12hFD and 36hFD birds increased compared to control birds (12hF and 36hF), but there were no significant differences in plasma CORT of 12hFD and 36hFD birds at 6 weeks of age compared to 6 week controls. DNMT1, DMAP1, and DNMT3B expression in the anterior pituitary increased by 12hFD, but decreased at 36hFD compared to their controls (P < 0.05). In liver, DNMT1, DNMT3A, and DNMT3B expression decreased by 12hFD, however, no significant changes occurred at 36hFD. Expression of DMAP1, DNMT3A, and DNMT3B in anterior pituitary and DMAP1 and DNMT3A expression in liver at 6 weeks of age were higher in 36hFD stressed birds compared to controls as well as 12hFD stressed birds. Hepatic GR expression decreased by 12hFD and increased by 36hFD (p < 0.05). Expression patterns of GR in the liver of FD stress-induced birds persisted until 6 weeks of age, suggesting the possible lifelong involvement of liver GR in early-life nutritional stress response of birds. Taken together, results suggest that DNA methylation regulator genes are tissue-specifically responsive to acute and chronic stress, and hepatic GR may play a critical role in regulating the early-life nutritional stress response of birds. In addition, the downregulation of DNMT1 and DMAP1 may be one of the adaptive mechanisms to chronic early-life nutritional stress via passive demethylation. PMID:29270191

  6. Nonlinear random response prediction using MSC/NASTRAN

    NASA Technical Reports Server (NTRS)

    Robinson, J. H.; Chiang, C. K.; Rizzi, S. A.

    1993-01-01

    An equivalent linearization technique was incorporated into MSC/NASTRAN to predict the nonlinear random response of structures by means of Direct Matrix Abstract Programming (DMAP) modifications and inclusion of the nonlinear differential stiffness module inside the iteration loop. An iterative process was used to determine the rms displacements. Numerical results obtained for validation on simple plates and beams are in good agreement with existing solutions in both the linear and linearized regions. The versatility of the implementation will enable the analyst to determine the nonlinear random responses for complex structures under combined loads. The thermo-acoustic response of a hexagonal thermal protection system panel is used to highlight some of the features of the program.

  7. Computer vision-based diameter maps to study fluoroscopic recordings of small intestinal motility from conscious experimental animals.

    PubMed

    Ramírez, I; Pantrigo, J J; Montemayor, A S; López-Pérez, A E; Martín-Fontelles, M I; Brookes, S J H; Abalo, R

    2017-08-01

    When available, fluoroscopic recordings are a relatively cheap, non-invasive and technically straightforward way to study gastrointestinal motility. Spatiotemporal maps have been used to characterize motility of intestinal preparations in vitro, or in anesthetized animals in vivo. Here, a new automated computer-based method was used to construct spatiotemporal motility maps from fluoroscopic recordings obtained in conscious rats. Conscious, non-fasted, adult, male Wistar rats (n=8) received intragastric administration of barium contrast, and 1-2 hours later, when several loops of the small intestine were well-defined, a 2 minutes-fluoroscopic recording was obtained. Spatiotemporal diameter maps (Dmaps) were automatically calculated from the recordings. Three recordings were also manually analyzed for comparison. Frequency analysis was performed in order to calculate relevant motility parameters. In each conscious rat, a stable recording (17-20 seconds) was analyzed. The Dmaps manually and automatically obtained from the same recording were comparable, but the automated process was faster and provided higher resolution. Two frequencies of motor activity dominated; lower frequency contractions (15.2±0.9 cpm) had an amplitude approximately five times greater than higher frequency events (32.8±0.7 cpm). The automated method developed here needed little investigator input, provided high-resolution results with short computing times, and automatically compensated for breathing and other small movements, allowing recordings to be made without anesthesia. Although slow and/or infrequent events could not be detected in the short recording periods analyzed to date (17-20 seconds), this novel system enhances the analysis of in vivo motility in conscious animals. © 2017 John Wiley & Sons Ltd.

  8. catena-Poly[[bis­[4-(dimethyl­amino)­pyridine-κN 1]cobalt(II)]-di-μ-azido-κ4 N 1:N 3

    PubMed Central

    Guenifa, Fatiha; Zeghouan, Ouahida; Hadjadj, Nasreddine; Bendjeddou, Lamia; Merazig, Hocine

    2013-01-01

    The title layered polymer, [Co(N3)2(C7H10N2)2]n, contains CoII, azide and 4-(dimethyl­amino)­pyridine (4-DMAP) species with site symmetries m2m, 2 and m, respectively. The Co2+ ion adopts an octa­hedral coordination geometry in which four N atoms from azide ligands lie in the equatorial plane and two 4-DMAP N atoms occupy the axial positions. The CoII atoms are connected by two bridging azide ligands, resulting in a chain parallel to the c axis. PMID:23476514

  9. Structural and physicochemical characterization of pyridine derivative salts of anti-inflammatory drugs

    NASA Astrophysics Data System (ADS)

    Nechipadappu, Sunil Kumar; Trivedi, Darshak R.

    2017-08-01

    Salts of common anti-inflammatory drugs mefenamic acid (MFA), tolfenamic acid (TFA) and naproxen (NPX) with various pyridine derivatives (4-amino pyridine (4AP), 4-dimethylaminopyridine (DMAP) and 2-amino pyridine (2AP)) were synthesized by crystal engineering approach based on the pKa values of API's and the salt former. All the salts were characterized systematically by various spectroscopic methods including FT-IR and 1H NMR and the crystal structure was determined by single-crystal X-ray diffraction techniques (SCXRD). DMAP salt of NPX and 2AP salts of MFA and TFA were not obtained in the salt screening experiments. All the molecular salts exhibited 1:1 molecular stoichiometry in the asymmetric unit and except NPX-2AP salt, all the molecular salts included a water molecule in the crystal lattice. Physicochemical and structural properties between drug-drug molecular salts of MFA-4AP, TFA-4AP and NPX-4AP have been evaluated and it was found that these molecular salts were found to be stable for a time period of six months at ambient condition and further hydration of molecular salts were not observed even at accelerated humid conditions (∼75% RH). It was found that 4AP salts of MFA and TFA and DMAP salts of MFA and TFA are isostructural.

  10. MSC/NASTRAN DMAP Alter Used for Closed-Form Static Analysis With Inertia Relief and Displacement-Dependent Loads

    NASA Technical Reports Server (NTRS)

    1996-01-01

    Solving for the displacements of free-free coupled systems acted upon by static loads is a common task in the aerospace industry. Often, these problems are solved by static analysis with inertia relief. This technique allows for a free-free static analysis by balancing the applied loads with the inertia loads generated by the applied loads. For some engineering applications, the displacements of the free-free coupled system induce additional static loads. Hence, the applied loads are equal to the original loads plus the displacement-dependent loads. A launch vehicle being acted upon by an aerodynamic loading can have such applied loads. The final displacements of such systems are commonly determined with iterative solution techniques. Unfortunately, these techniques can be time consuming and labor intensive. Because the coupled system equations for free-free systems with displacement-dependent loads can be written in closed form, it is advantageous to solve for the displacements in this manner. Implementing closed-form equations in static analysis with inertia relief is analogous to implementing transfer functions in dynamic analysis. An MSC/NASTRAN (MacNeal-Schwendler Corporation/NASA Structural Analysis) DMAP (Direct Matrix Abstraction Program) Alter was used to include displacement-dependent loads in static analysis with inertia relief. It efficiently solved a common aerospace problem that typically has been solved with an iterative technique.

  11. NASTRAN DMAP Fuzzy Structures Analysis: Summary of Research

    NASA Technical Reports Server (NTRS)

    Sparrow, Victor W.

    2001-01-01

    The main proposed tasks of Cooperative Agreement NCC1-382 were: (1) developing MSC/NASTRAN DMAP language scripts to implement the Soize fuzzy structures approach for modeling the dynamics of complex structures; (2) benchmarking the results of the new code to those for a cantilevered beam in the literature; and (3) testing and validating the new code by comparing the fuzzy structures results to NASA Langley experimental and conventional finite element results for two model test structures representative of aircraft fuselage sidewall construction: (A) a small aluminum test panel (SLP, single longeron panel) with a single longitudinal stringer attached with bolts; and (B) a 47 by 72 inch flat aluminum fuselage panel (AFP, aluminum fuselage panel) including six longitudinal stringers and four frame stiffeners attached with rivets.

  12. The influence of steric hindrance on kinetics and isotope effects in the reaction of 2,2-bis(4-dimethylaminophenyl)-1-nitro-1-(4-nitrophenyl)ethane with DBU base in acetonitrile

    NASA Astrophysics Data System (ADS)

    Nowak, Iwona; Jarczewski, Arnold

    2014-11-01

    The pKa value for 2,2-bis(4-dimethylaminophenyl)-1-nitro-1-(4-nitrophenyl)ethane, (dmap)2 (pKa = 25.11) has been measured spectrophotometrically using buffer solutions of a few strong amine bases: 1,8-diazabicyclo[5.4.0]undec-7-ene, (DBU); 1,1,3,3-tetramethylguanidine, (TMG); 1,5,7-triazabicyclo[4.4.0]dec-5-ene, (TBD); 7-methyl-1,5,7-triazabicyclo[4.4.0]dec-5-ene, (MTBD) and their salts. The low energy conformers of nitrophenyl nitroalkanes have been determined using the semiempirical PM6 methods, (B3-LYP) density functional theory (DFT) together with the 6-31G(d,p) basis set. The participation of the low energy conformer in the proton transfer reaction to DBU base has been discussed. The kinetic data for proton transfer reactions between (dmap)2 and DBU in acetonitrile (MeCN) at pseudo-first order conditions have been presented. The influence of steric hindrance brought by reacting C-acid and organic base on the stability of the transition state has been discussed. The rates of second-order rate constants for series of nitrophenyl nitroalkanes, NO2PhCHRNO2 (R = Me; Et; iPr; dimethylaminophenyl = (dmap)2) are presented and discussed.

  13. Improved Equivalent Linearization Implementations Using Nonlinear Stiffness Evaluation

    NASA Technical Reports Server (NTRS)

    Rizzi, Stephen A.; Muravyov, Alexander A.

    2001-01-01

    This report documents two new implementations of equivalent linearization for solving geometrically nonlinear random vibration problems of complicated structures. The implementations are given the acronym ELSTEP, for "Equivalent Linearization using a STiffness Evaluation Procedure." Both implementations of ELSTEP are fundamentally the same in that they use a novel nonlinear stiffness evaluation procedure to numerically compute otherwise inaccessible nonlinear stiffness terms from commercial finite element programs. The commercial finite element program MSC/NASTRAN (NASTRAN) was chosen as the core of ELSTEP. The FORTRAN implementation calculates the nonlinear stiffness terms and performs the equivalent linearization analysis outside of NASTRAN. The Direct Matrix Abstraction Program (DMAP) implementation performs these operations within NASTRAN. Both provide nearly identical results. Within each implementation, two error minimization approaches for the equivalent linearization procedure are available - force and strain energy error minimization. Sample results for a simply supported rectangular plate are included to illustrate the analysis procedure.

  14. HIGH-PRECISION BIOLOGICAL EVENT EXTRACTION: EFFECTS OF SYSTEM AND OF DATA

    PubMed Central

    Cohen, K. Bretonnel; Verspoor, Karin; Johnson, Helen L.; Roeder, Chris; Ogren, Philip V.; Baumgartner, William A.; White, Elizabeth; Tipney, Hannah; Hunter, Lawrence

    2013-01-01

    We approached the problems of event detection, argument identification, and negation and speculation detection in the BioNLP’09 information extraction challenge through concept recognition and analysis. Our methodology involved using the OpenDMAP semantic parser with manually written rules. The original OpenDMAP system was updated for this challenge with a broad ontology defined for the events of interest, new linguistic patterns for those events, and specialized coordination handling. We achieved state-of-the-art precision for two of the three tasks, scoring the highest of 24 teams at precision of 71.81 on Task 1 and the highest of 6 teams at precision of 70.97 on Task 2. We provide a detailed analysis of the training data and show that a number of trigger words were ambiguous as to event type, even when their arguments are constrained by semantic class. The data is also shown to have a number of missing annotations. Analysis of a sampling of the comparatively small number of false positives returned by our system shows that major causes of this type of error were failing to recognize second themes in two-theme events, failing to recognize events when they were the arguments to other events, failure to recognize nontheme arguments, and sentence segmentation errors. We show that specifically handling coordination had a small but important impact on the overall performance of the system. The OpenDMAP system and the rule set are available at http://bionlp.sourceforge.net. PMID:25937701

  15. Time-resolved mapping of water diffusion coefficients in a working soft actuator device.

    PubMed

    Naji, Leila; Chudek, John A; Baker, Richard T

    2008-08-14

    Diffusion-weighted imaging was employed to spatially map the distribution of the diffusion coefficient of water, D, in bare, water-soaked, Li(+)-exchanged, cast Nafion and in an ionic polymer-metal composite (IPMC) soft actuator element, prepared from this bare Nafion by impregnation with Pt electrodes. D was evaluated in two orthogonal directions: along one of the long dimensions of the sample (Dx) and through its thickness (Dz). D-maps of the IPMC element were obtained both in the absence of an applied potential and in situ during the application of a 3 V dc potential across the thickness of the sample. In the bare Nafion, D-maps showed uniform values of both Dx and Dz of about 6 x 10 (-10) m(2) s(-1). In the IPMC two effects were observed: (i) D at the electroded surfaces of the IPMC was higher than at the center of the sample; (ii) this difference was much greater in Dz than in Dx . Both effects were explained by the influence of the impregnated Pt electrodes on polymer structure. The D-maps in the electrochemical measurements showed high values of D (up to 8 x 10(-10) m(2) s(-1)) at the cathode and low values (from 1 x 10(-10) m(2) s(-1)) at the anode. This was explained in terms of the effect on the Nafion nanostructure of the forced electro-migration of Li(H2O)x(+) species toward the cathode.

  16. Fall Prevention Self-Assessments Via Mobile 3D Visualization Technologies: Community Dwelling Older Adults’ Perceptions of Opportunities and Challenges

    PubMed Central

    Hamm, Julian; Atwal, Anita

    2017-01-01

    Background In the field of occupational therapy, the assistive equipment provision process (AEPP) is a prominent preventive strategy used to promote independent living and to identify and alleviate fall risk factors via the provision of assistive equipment within the home environment. Current practice involves the use of paper-based forms that include 2D measurement guidance diagrams that aim to communicate the precise points and dimensions that must be measured in order to make AEPP assessments. There are, however, issues such as “poor fit” of equipment due to inaccurate measurements taken and recorded, resulting in more than 50% of equipment installed within the home being abandoned by patients. This paper presents a novel 3D measurement aid prototype (3D-MAP) that provides enhanced measurement and assessment guidance to patients via the use of 3D visualization technologies. Objective The purpose of this study was to explore the perceptions of older adults with regard to the barriers and opportunities of using the 3D-MAP application as a tool that enables patient self-delivery of the AEPP. Methods Thirty-three community-dwelling older adults participated in interactive sessions with a bespoke 3D-MAP application utilizing the retrospective think-aloud protocol and semistructured focus group discussions. The system usability scale (SUS) questionnaire was used to evaluate the application’s usability. Thematic template analysis was carried out on the SUS item discussions, think-aloud, and semistructured focus group data. Results The quantitative SUS results revealed that the application may be described as having “marginal-high” and “good” levels of usability, along with strong agreement with items relating to the usability (P=.004) and learnability (P<.001) of the application. Four high-level themes emerged from think-aloud and focus groups discussions: (1) perceived usefulness (PU), (2) perceived ease of use (PEOU), (3) application use (AU) and (4) self-assessment (SA). The application was seen as a useful tool to enhance visualization of measurement guidance and also to promote independent living, ownership of care, and potentially reduce waiting times. Several design and functionality recommendations emerged from the study, such as a need to manipulate the view and position of the 3D furniture models, and a need for clearer visual prompts and alternative keyboard interface for measurement entry. Conclusions Participants perceived the 3D-MAP application as a useful tool that has the potential to make significant improvements to the AEPP, not only in terms of accuracy of measurement, but also by potentially enabling older adult patients to carry out the data collection element of the AEPP themselves. Further research is needed to further adapt the 3D-MAP application in line with the study outcomes and to establish its clinical utility with regards to effectiveness, efficiency, accuracy, and reliability of measurements that are recorded using the application and to compare it with 2D measurement guidance leaflets. PMID:28630034

  17. Mesoporous gold sponges: electric charge-assisted seed mediated synthesis and application as surface-enhanced Raman scattering substrates

    NASA Astrophysics Data System (ADS)

    Yi, Zao; Luo, Jiangshan; Tan, Xiulan; Yi, Yong; Yao, Weitang; Kang, Xiaoli; Ye, Xin; Zhu, Wenkun; Duan, Tao; Yi, Yougen; Tang, Yongjian

    2015-11-01

    Mesoporous gold sponges were prepared using 4-dimethylaminopyridine (DMAP)-stabilized Au seeds. This is a general process, which involves a simple template-free method, room temperature reduction of HAuCl4·4H2O with hydroxylamine. The formation process of mesoporous gold sponges could be accounted for the electrostatic interaction (the small Au nanoparticles (~3 nm) and the positively charged DMAP-stabilized Au seeds) and Ostwald ripening process. The mesoporous gold sponges had appeared to undergo electrostatic adsorption initially, sequentially linear aggregation, welding and Ostwald ripening, then, they randomly cross link into self-supporting, three-dimensional networks with time. The mesoporous gold sponges exhibit higher surface area than the literature. In addition, application of the spongelike networks as an active material for surface-enhanced Raman scattering has been investigated by employing 4-aminothiophenol (4-ATP) molecules as a probe.

  18. Mesoporous gold sponges: electric charge-assisted seed mediated synthesis and application as surface-enhanced Raman scattering substrates

    PubMed Central

    Yi, Zao; Luo, Jiangshan; Tan, Xiulan; Yi, Yong; Yao, Weitang; Kang, Xiaoli; Ye, Xin; Zhu, Wenkun; Duan, Tao; Yi, Yougen; Tang, Yongjian

    2015-01-01

    Mesoporous gold sponges were prepared using 4-dimethylaminopyridine (DMAP)-stabilized Au seeds. This is a general process, which involves a simple template-free method, room temperature reduction of HAuCl4·4H2O with hydroxylamine. The formation process of mesoporous gold sponges could be accounted for the electrostatic interaction (the small Au nanoparticles (~3 nm) and the positively charged DMAP-stabilized Au seeds) and Ostwald ripening process. The mesoporous gold sponges had appeared to undergo electrostatic adsorption initially, sequentially linear aggregation, welding and Ostwald ripening, then, they randomly cross link into self-supporting, three-dimensional networks with time. The mesoporous gold sponges exhibit higher surface area than the literature. In addition, application of the spongelike networks as an active material for surface-enhanced Raman scattering has been investigated by employing 4-aminothiophenol (4-ATP) molecules as a probe. PMID:26538365

  19. The NASTRAN User's Manual Level 16.0 and Supplement

    NASA Technical Reports Server (NTRS)

    1976-01-01

    The user's manual is restricted to those items related to the use of NASTRAN that are independent of the computing system being used. The features of NASTRAN described include: (1) procedures for defining and loading a structural model and a functional reference for every card that is used for structural modeling; (2) the NASTRAN data deck, including the details for each of the data cards; (3) the NASTRAN control cards that are associated with the use of the program; (4) rigid format procedures, along with specific instructions for the use of each rigid format: (5) procedures for using instructions for the use of each rigid format; (5) procedures for using the NASTRAN plotting capability; (6) procedures governing the creation of DMAP programs; and (7) the NASTRAN diagnostic messages. The NASTRAN dictionary of mnemonics, acronyms, phrases, and other commonly used NASTRAN terms is included along with a limited number of sample problems.

  20. Simultaneous removal of ammonia and N-nitrosamine precursors from high ammonia water by zeolite and powdered activated carbon.

    PubMed

    Xue, Runmiao; Donovan, Ariel; Zhang, Haiting; Ma, Yinfa; Adams, Craig; Yang, John; Hua, Bin; Inniss, Enos; Eichholz, Todd; Shi, Honglan

    2018-02-01

    When adding sufficient chlorine to achieve breakpoint chlorination to source water containing high concentration of ammonia during drinking water treatment, high concentrations of disinfection by-products (DBPs) may form. If N-nitrosamine precursors are present, highly toxic N-nitrosamines, primarily N-nitrosodimethylamine (NDMA), may also form. Removing their precursors before disinfection should be a more effective way to minimize these DBPs formation. In this study, zeolites and activated carbon were examined for ammonia and N-nitrosamine precursor removal when incorporated into drinking water treatment processes. The test results indicate that Mordenite zeolite can remove ammonia and five of seven N-nitrosamine precursors efficiently by single step adsorption test. The practical applicability was evaluated by simulation of typical drinking water treatment processes using six-gang stirring system. The Mordenite zeolite was applied at the steps of lime softening, alum coagulation, and alum coagulation with powdered activated carbon (PAC) sorption. While the lime softening process resulted in poor zeolite performance, alum coagulation did not impact ammonia and N-nitrosamine precursor removal. During alum coagulation, more than 67% ammonia and 70%-100% N-nitrosamine precursors were removed by Mordenite zeolite (except 3-(dimethylaminomethyl)indole (DMAI) and 4-dimethylaminoantipyrine (DMAP)). PAC effectively removed DMAI and DMAP when added during alum coagulation. A combination of the zeolite and PAC selected efficiently removed ammonia and all tested seven N-nitrosamine precursors (dimethylamine (DMA), ethylmethylamine (EMA), diethylamine (DEA), dipropylamine (DPA), trimethylamine (TMA), DMAP, and DMAI) during the alum coagulation process. Copyright © 2017. Published by Elsevier B.V.

  1. Somatic cell cloning in Buffalo (Bubalus bubalis): effects of interspecies cytoplasmic recipients and activation procedures.

    PubMed

    Kitiyanant, Y; Saikhun, J; Chaisalee, B; White, K L; Pavasuthipaisit, K

    2001-01-01

    Successful nuclear transfer (NT) of somatic cell nuclei from various mammalian species to enucleated bovine oocytes provides a universal cytoplast for NT in endangered or extinct species. Buffalo fetal fibroblasts were isolated from a day 40 fetus and were synchronized in presumptive G(0) by serum deprivation. Buffalo and bovine oocytes from abattoir ovaries were matured in vitro and enucleated at 22 h. In the first experiment, we compared the ability of buffalo and bovine oocyte cytoplasm to support in vitro development of NT embryos produced by buffalo fetal fibroblasts as donor nuclei. There were no significant differences (p > 0.05) between the NT embryos derived from buffalo and bovine oocytes, in fusion (74% versus 71%) and cleavage (77% versus 75%) rates, respectively. No significant differences were also observed in blastocyst development (39% versus 33%) and the mean cell numbers of day 7 cloned blastocysts (88.5 +/- 25.7 versus 51.7 +/- 5.4). In the second experiment, we evaluated the effects of activation with calcium ionophore A23187 on development of NT embryos after electrical fusion. A significantly higher (p < 0.05) percentage of blastocyst development was observed in the NT embryos activated by calcium ionophore and 6-DMAP when compared with 6-DMAP alone (33% versus 17%). The results indicate that the somatic nuclei from buffalo can be reprogrammed after transfer to enucleated bovine oocytes, resulting in the production of cloned buffalo blastocysts similar to those transferred into buffalo oocytes. Calcium ionophore used in conjunction with 6-DMAP effectively induces NT embryo development.

  2. Fall Prevention Self-Assessments Via Mobile 3D Visualization Technologies: Community Dwelling Older Adults' Perceptions of Opportunities and Challenges.

    PubMed

    Hamm, Julian; Money, Arthur; Atwal, Anita

    2017-06-19

    In the field of occupational therapy, the assistive equipment provision process (AEPP) is a prominent preventive strategy used to promote independent living and to identify and alleviate fall risk factors via the provision of assistive equipment within the home environment. Current practice involves the use of paper-based forms that include 2D measurement guidance diagrams that aim to communicate the precise points and dimensions that must be measured in order to make AEPP assessments. There are, however, issues such as "poor fit" of equipment due to inaccurate measurements taken and recorded, resulting in more than 50% of equipment installed within the home being abandoned by patients. This paper presents a novel 3D measurement aid prototype (3D-MAP) that provides enhanced measurement and assessment guidance to patients via the use of 3D visualization technologies. The purpose of this study was to explore the perceptions of older adults with regard to the barriers and opportunities of using the 3D-MAP application as a tool that enables patient self-delivery of the AEPP. Thirty-three community-dwelling older adults participated in interactive sessions with a bespoke 3D-MAP application utilizing the retrospective think-aloud protocol and semistructured focus group discussions. The system usability scale (SUS) questionnaire was used to evaluate the application's usability. Thematic template analysis was carried out on the SUS item discussions, think-aloud, and semistructured focus group data. The quantitative SUS results revealed that the application may be described as having "marginal-high" and "good" levels of usability, along with strong agreement with items relating to the usability (P=.004) and learnability (P<.001) of the application. Four high-level themes emerged from think-aloud and focus groups discussions: (1) perceived usefulness (PU), (2) perceived ease of use (PEOU), (3) application use (AU) and (4) self-assessment (SA). The application was seen as a useful tool to enhance visualization of measurement guidance and also to promote independent living, ownership of care, and potentially reduce waiting times. Several design and functionality recommendations emerged from the study, such as a need to manipulate the view and position of the 3D furniture models, and a need for clearer visual prompts and alternative keyboard interface for measurement entry. Participants perceived the 3D-MAP application as a useful tool that has the potential to make significant improvements to the AEPP, not only in terms of accuracy of measurement, but also by potentially enabling older adult patients to carry out the data collection element of the AEPP themselves. Further research is needed to further adapt the 3D-MAP application in line with the study outcomes and to establish its clinical utility with regards to effectiveness, efficiency, accuracy, and reliability of measurements that are recorded using the application and to compare it with 2D measurement guidance leaflets. ©Julian Hamm, Arthur Money, Anita Atwal. Originally published in JMIR Human Factors (http://humanfactors.jmir.org), 19.06.2017.

  3. Biologic Monitoring to Characterize Organophosphorus Pesticide Exposure among Children and Workers: An Analysis of Recent Studies in Washington State

    PubMed Central

    Fenske, Richard A.; Lu, Chensheng; Curl, Cynthia L.; Shirai, Jeffry H.; Kissel, John C.

    2005-01-01

    We examined findings from five organophosphorus pesticide biomonitoring studies conducted in Washington State between 1994 and 1999. We compared urinary dimethylthiophosphate (DMTP) concentrations for all study groups and composite dimethyl alkylphosphate (DMAP) concentrations for selected groups. Children of pesticide applicators had substantially higher metabolite levels than did Seattle children and farmworker children (median DMTP, 25 μg/L; p < 0.0001). Metabolite levels of children living in agricultural communities were elevated during periods of crop spraying. Median DMTP concentrations for Seattle children and farmworker children did not differ significantly (6.1 and 5.8 μg/L DMTP, respectively; p = 0.73); however, the DMAP concentrations were higher for Seattle children than for farmworker children (117 and 87 nmol/L DMAP, respectively; p = 0.007). DMTP concentrations of U.S. children 6–11 years of age (1999–2000 National Health and Nutrition Examination Survey population) were higher than those of Seattle children and farmworker children at the 75th, 90th, and 95th percentiles. DMTP concentrations for workers actively engaged in apple thinning were 50 times higher than DMTP concentrations for farmworkers sampled outside of peak exposure periods. We conclude that workers who have direct contact with pesticides should continue to be the focus of public health interventions and that elevated child exposures in agricultural communities may occur during active crop-spraying periods and from living with a pesticide applicator. Timing of sample collection is critical for the proper interpretation of pesticide biomarkers excreted relatively soon after exposure. We surmise that differences in dietary exposure can explain the similar exposures observed among farmworker children, children living in the Seattle metropolitan area, and children sampled nationally. PMID:16263526

  4. 3D-Mapping of Dolomitized Structures in Lower Cambrian Phosphorites

    NASA Astrophysics Data System (ADS)

    Hippler, Dorothee; Stammeier, Jessica A.; Brunner, Roland; Rosc, Jördis; Franz, Gerhard; Dietzel, Martin

    2016-04-01

    Dolomitization is a widespread phenomenon in ancient sedimentary rocks, particularly close to the Precambrian-Cambrian boundary. Dolomite can form in synsedimentary or hydrothermal environments, preferentially via the replacement of solid carbonate precursor phases. Synsedimentary dolomite formation is often associated with microbial activity, such as bacterial sulfate reduction or methanogenesis. In this study, we investigate dolomitic phosphorites from the Lowermost Cambrian Tal Group, Mussoori Syncline, Lesser Himalaya, India, using micro-CT 3D-mapping, in order to unravel the complex diagenetic history of the rocks. The selected sample shows alternating layering of phosphatic mudstones and sparitic dolostone, in which brecciated layers of phosphorite or phosphatic mudstones are immersed in a dolomite-rich matrix. Lamination occurs on a sub-millimetre scale, with lamination sometimes wavy to crinkly. This fabric is interpreted as former microbial mats, providing the environment for early diagenetic phosphatization. Preliminary electron backscatter imaging with scanning microscopy revealed that dolomite crystals often occur in spherical to ellipsoidal structures, typically with a high porosity. This dolomite is associated with botryoidal apatite, organic matter and small amounts of calcite. Micro-CT 3D-mappings reveal that dolomite structures are cigar-shaped, elongated and up to 600 μm long. They are further arranged in a Mikado-like oriented framework spanning a layer thickness of a few millimetres. Analyses of ambient pore space, with similar elongated outlines and filled with organic matter, suggest a potential coherence of ambient pore space and shape of the dolomite structures. Allowing for other associated mineral phases, such as pyrite and silicates, and their spatial distribution, the present approach can be used to unravel distinct diagenetic reaction pathways, and might thus constrain the proxy potential of these Lower Cambrian dolomitic phosphorites to reconstruct ambient environmental at the time of deposition.

  5. Effectiveness of intramuscularly administered cyanide antidotes and the rate of methemoglobin formation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Vick, J.A.; Von Bredow, J.D.

    1993-05-13

    Successful first aid therapy for cyanide intoxication is dependent upon the immediate administration of antidotes which directly or indirectly interact with the cyanide ion to remove it from circulation. Exceptionally rapid methemoglobin formers (hydroxylamine hydrochloride 'HA) and Dimethylaminophenol (DMAP) are usually able to prevent the lethal effect of cyanide following intramuscular injections in doses sufficient to induce 20% methemoglobin (HA = 20 mg/kg and DMAP= 2 mg/kg). Sodium nitrite, the methemoglobin inducer approved by the FDA and is available for military use, must be administered by intravenous infusion since it is not an effective cyanide antidote by the intramuscular route.more » In the normal un-intoxicated animal an intramuscular injection of 20 mg/kg sodium nitrite will form 20% methemoglobin at a rapid rate; however, in the presence of acute cyanide intoxication the associated severe bradycardia appears to limit the rate of absorption of sodium nitrite from the intramuscular site which prevents the rapid formation of sufficient methemoglobin to counteract cyanide intoxication.« less

  6. Combining Acceleration and Displacement Dependent Modal Frequency Responses Using an MSC/NASTRAN DMAP Alter

    NASA Technical Reports Server (NTRS)

    Barnett, Alan R.; Widrick, Timothy W.; Ludwiczak, Damian R.

    1996-01-01

    Solving for dynamic responses of free-free launch vehicle/spacecraft systems acted upon by buffeting winds is commonly performed throughout the aerospace industry. Due to the unpredictable nature of this wind loading event, these problems are typically solved using frequency response random analysis techniques. To generate dynamic responses for spacecraft with statically-indeterminate interfaces, spacecraft contractors prefer to develop models which have response transformation matrices developed for mode acceleration data recovery. This method transforms spacecraft boundary accelerations and displacements into internal responses. Unfortunately, standard MSC/NASTRAN modal frequency response solution sequences cannot be used to combine acceleration- and displacement-dependent responses required for spacecraft mode acceleration data recovery. External user-written computer codes can be used with MSC/NASTRAN output to perform such combinations, but these methods can be labor and computer resource intensive. Taking advantage of the analytical and computer resource efficiencies inherent within MS C/NASTRAN, a DMAP Alter has been developed to combine acceleration- and displacement-dependent modal frequency responses for performing spacecraft mode acceleration data recovery. The Alter has been used successfully to efficiently solve a common aerospace buffeting wind analysis.

  7. The Contrasting Alkylations of 4-(Dimethylaminomethyl)pyridine and 4-(Dimethylamino)pyridine: An Organic Chemistry Experiment

    ERIC Educational Resources Information Center

    Jantzi, Kevin L.; Wiltrakis, Susan; Wolf, Lauren; Weber, Anna; Cardinal, Josh; Krieter, Katie

    2011-01-01

    A critical factor for the increased nucleophilicity of the pyridine nitrogen in 4-(dimethylamino)pyridine (DMAP) is electron donation via resonance from the amino group into the aromatic ring that increases electron density on the pyridine nitrogen. To explore how important this resonance effect is, 4-(dimethylaminomethyl)pyridine (DMAMP) was…

  8. Enhanced Modeling of First-Order Plant Equations of Motion for Aeroelastic and Aeroservoelastic Applications

    NASA Technical Reports Server (NTRS)

    Pototzky, Anthony S.

    2010-01-01

    A methodology is described for generating first-order plant equations of motion for aeroelastic and aeroservoelastic applications. The description begins with the process of generating data files representing specialized mode-shapes, such as rigid-body and control surface modes, using both PATRAN and NASTRAN analysis. NASTRAN executes the 146 solution sequence using numerous Direct Matrix Abstraction Program (DMAP) calls to import the mode-shape files and to perform the aeroelastic response analysis. The aeroelastic response analysis calculates and extracts structural frequencies, generalized masses, frequency-dependent generalized aerodynamic force (GAF) coefficients, sensor deflections and load coefficients data as text-formatted data files. The data files are then re-sequenced and re-formatted using a custom written FORTRAN program. The text-formatted data files are stored and coefficients for s-plane equations are fitted to the frequency-dependent GAF coefficients using two Interactions of Structures, Aerodynamics and Controls (ISAC) programs. With tabular files from stored data created by ISAC, MATLAB generates the first-order aeroservoelastic plant equations of motion. These equations include control-surface actuator, turbulence, sensor and load modeling. Altitude varying root-locus plot and PSD plot results for a model of the F-18 aircraft are presented to demonstrate the capability.

  9. NASTRAN multipartitioning and one-shot substructuring

    NASA Technical Reports Server (NTRS)

    Levy, A.

    1973-01-01

    For intermediate size problems where all the data is accessible, the present method of substructuring in three separate phases (for static analysis) is unneccessarily cumbersome. The versatility of NASTRAN's DMAP and internal logic lends itself to finding a practical alternative to these procedures whereby self-contained special-purpose ALTER packages can be written to be run in one pass. Two examples are presented here under the titles of multipartitioning and one-shot substructuring. The flow of multipartitioning resembles that of the present three-phase substructuring. The basic effect is to partition the structure into substructures and operate on each substructure separately. This can be used to reduce the bandwidth of a given problem as well as to store information which will allow a change to be made in one of the substructures in a later run. This latter procedure is carried out in a second program titled one-shot substructuring.

  10. An enhancement of NASTRAN for the seismic analysis of structures. [nuclear power plants

    NASA Technical Reports Server (NTRS)

    Burroughs, J. W.

    1980-01-01

    New modules, bulk data cards and DMAP sequence were added to NASTRAN to aid in the seismic analysis of nuclear power plant structures. These allow input consisting of acceleration time histories and result in the generation of acceleration floor response spectra. The resulting system contains numerous user convenience features, as well as being reasonably efficient.

  11. Acylation, Diastereoselective Alkylation, and Cleavage of an Oxazolidinone Chiral Auxiliary: A Multistep Asymmetric Synthesis Experiment for Advanced Undergraduates

    ERIC Educational Resources Information Center

    Smith, Thomas E.; Richardson, David P.; Truran, George A.; Belecki, Katherine; Onishi, Megumi

    2008-01-01

    An introduction to the concepts and experimental techniques of diastereoselective synthesis using a chiral auxiliary is described. The 4-benzyl-2-oxazolidinone chiral auxiliary developed by Evans is acylated with propionic anhydride under mild conditions using DMAP as an acyl transfer catalyst. Deprotonation with NaN(TMS)[subscript 2] at -78…

  12. Closed-form Static Analysis with Inertia Relief and Displacement-Dependent Loads Using a MSC/NASTRAN DMAP Alter

    NASA Technical Reports Server (NTRS)

    Barnett, Alan R.; Widrick, Timothy W.; Ludwiczak, Damian R.

    1995-01-01

    Solving for the displacements of free-free coupled systems acted upon by static loads is commonly performed throughout the aerospace industry. Many times, these problems are solved using static analysis with inertia relief. This solution technique allows for a free-free static analysis by balancing the applied loads with inertia loads generated by the applied loads. For some engineering applications, the displacements of the free-free coupled system induce additional static loads. Hence, the applied loads are equal to the original loads plus displacement-dependent loads. Solving for the final displacements of such systems is commonly performed using iterative solution techniques. Unfortunately, these techniques can be time-consuming and labor-intensive. Since the coupled system equations for free-free systems with displacement-dependent loads can be written in closed-form, it is advantageous to solve for the displacements in this manner. Implementing closed-form equations in static analysis with inertia relief is analogous to implementing transfer functions in dynamic analysis. Using a MSC/NASTRAN DMAP Alter, displacement-dependent loads have been included in static analysis with inertia relief. Such an Alter has been used successfully to solve efficiently a common aerospace problem typically solved using an iterative technique.

  13. Identification of Cyclin A Binders with a Fluorescent Peptide Sensor.

    PubMed

    Pazos, Elena; Mascareñas, José L; Vázquez, M Eugenio

    2016-01-01

    A peptide sensor that integrates the 4-dimethylaminophthalimide (4-DMAP) fluorophore in a short cyclin A binding sequence displays a large fluorescence emission increase upon interacting with the cyclin A Binding Groove (CBG). Competitive displacement assays of this probe allow the straightforward identification of peptides that interact with the CBG, which could potentially block the recognition of CDK/cyclin A kinase substrates.

  14. NASTRAN thermal analyzer: Theory and application including a guide to modeling engineering problems, volume 2. [sample problem library guide

    NASA Technical Reports Server (NTRS)

    Jackson, C. E., Jr.

    1977-01-01

    A sample problem library containing 20 problems covering most facets of Nastran Thermal Analyzer modeling is presented. Areas discussed include radiative interchange, arbitrary nonlinear loads, transient temperature and steady-state structural plots, temperature-dependent conductivities, simulated multi-layer insulation, and constraint techniques. The use of the major control options and important DMAP alters is demonstrated.

  15. Rational design of a cyclin A fluorescent peptide sensor.

    PubMed

    Pazos, Elena; Pérez, Miguel; Gutiérrez-de-Terán, Hugo; Orzáez, Mar; Guevara, Tatiana; Mascareñas, José L; Vázquez, M Eugenio

    2011-10-26

    We report the design and development of a fluorescent sensor specifically designed to target cyclin A, a protein that plays a key role in the regulation of the cell cycle. Computational studies provide a molecular picture that explains the observed emission increase, suggesting that the 4-DMAP fluorophore in the peptide is protected from the bulk solvent when inserted into the hydrophobic binding groove of cyclin A.

  16. Synthesis and antiproliferative activity of a cyclic analog of dolastatin 10.

    PubMed

    Poncet, J; Hortala, L; Busquet, M; Guéritte-Voegelein, F; Thoret, S; Pierré, A; Atassi, G; Jouin, P

    1998-10-20

    A cyclic analog of the natural antiproliferative compound dolastatin 10 was synthesized by introducing an ester link between the N- and C-terminal residues which were modified accordingly. The final macrolactonization was performed by using isopropenyl chloroformate and DMAP as reagents. This analog exhibits submicromolar antiproliferative activity against the L1210 and HT29 cell lines and inhibits in vitro tubulin polymerization (IC50, 39 microM).

  17. Basic studies on the pyrolysis of lignin compounds

    Treesearch

    Byung-ho Hwang

    2003-01-01

    By pyrolyzing lignin model compounds 1-lV at 315°C, an investigation was carried out with some results. In the pyrolysis of lignin model compound I and 11, 0.47 mol of guaiacol, 0.57 mol of dimethoxyphenol (DMP), and 0.12 and 0.23 mol of dimethoxyaceton ophenone (DMAP) were produced respectively. In the pyrolysis of lignin model compound lll and lV, 0.26 mol of...

  18. Transient analysis mode participation for modal survey target mode selection using MSC/NASTRAN DMAP

    NASA Technical Reports Server (NTRS)

    Barnett, Alan R.; Ibrahim, Omar M.; Sullivan, Timothy L.; Goodnight, Thomas W.

    1994-01-01

    Many methods have been developed to aid analysts in identifying component modes which contribute significantly to component responses. These modes, typically targeted for dynamic model correlation via a modal survey, are known as target modes. Most methods used to identify target modes are based on component global dynamic behavior. It is sometimes unclear if these methods identify all modes contributing to responses important to the analyst. These responses are usually those in areas of hardware design concerns. One method used to check the completeness of target mode sets and identify modes contributing significantly to important component responses is mode participation. With this method, the participation of component modes in dynamic responses is quantified. Those modes which have high participation are likely modal survey target modes. Mode participation is most beneficial when it is used with responses from analyses simulating actual flight events. For spacecraft, these responses are generated via a structural dynamic coupled loads analysis. Using MSC/NASTRAN DMAP, a method has been developed for calculating mode participation based on transient coupled loads analysis results. The algorithm has been implemented to be compatible with an existing coupled loads methodology and has been used successfully to develop a set of modal survey target modes.

  19. Design of experiments as a tool for LC-MS/MS method development for the trace analysis of the potentially genotoxic 4-dimethylaminopyridine impurity in glucocorticoids.

    PubMed

    Székely, Gy; Henriques, B; Gil, M; Ramos, A; Alvarez, C

    2012-11-01

    The present study reports on a liquid chromatography-tandem mass spectrometry (LC-MS/MS) method development strategy supported by design of experiments (DoE) for the trace analysis of 4-dimethylaminopyridine (DMAP). The conventional approaches for development of LC-MS/MS methods are usually via trial and error, varying intentionally the experimental factors which is time consuming and interactions between experimental factors are not considered. The LC factors chosen for the DoE study include flow (F), gradient (G) and injection volume (V(inj)) while cone voltage (E(con)) and collision energy (E(col)) were chosen as MS parameters. All of the five factors were studied simultaneously. The method was optimized with respect to four responses: separation of peaks (Sep), peak area (A(peak)), length of the analysis (T) and the signal to noise ratio (S/N). A quadratic model, namely central composite face (CCF) featuring 29 runs was used instead of a less powerful linear model since the increase in the number of injections was insignificant. In order to determine the robustness of the method a new set of DoE experiments was carried out applying robustness around the optimal conditions was evaluated applying a fractional factorial of resolution III with 11 runs, wherein additional factors - such as column temperature and quadrupole resolution - were considered. The method utilizes a Phenomenex Gemini NX C-18 HPLC analytical column with electrospray ionization and a triple quadrupole mass detector in multiple reaction monitoring (MRM) mode, resulting in short analyses with a 10min runtime. Drawbacks of derivatization, namely incomplete reaction and time consuming sample preparation, have been avoided and the change from SIM to MRM mode resulted in increased sensitivity and lower LOQ. The DoE method development strategy led to a method allowing the trace analysis of DMAP at 0.5 ng/ml absolute concentration which corresponds to a 0.1 ppm limit of quantification in 5mg/ml mometasone furoate glucocorticoid. The obtained method was validated in a linear range of 0.1-10 ppm and presented a %RSD of 0.02% for system precision. Regarding DMAP recovery in mometasone furoate, spiked samples produced %recoveries between 83 and 113% in the range of 0.1-2 ppm. Copyright © 2012 Elsevier B.V. All rights reserved.

  20. X-ray Absorption Spectroscopy Combined with Time-Dependent Density Functional Theory Elucidates Differential Substitution Pathways of Au(I) and Au(III) with Zinc Fingers.

    PubMed

    Abbehausen, Camilla; de Paiva, Raphael Enoque Ferraz; Bjornsson, Ragnar; Gomes, Saulo Quintana; Du, Zhifeng; Corbi, Pedro Paulo; Lima, Frederico Alves; Farrell, Nicholas

    2018-01-02

    A combination of two elements' (Au, Zn) X-ray absorption spectroscopy (XAS) and time-dependent density functional theory (TD-DFT) allowed the elucidation of differential substitution pathways of Au(I) and Au(III) compounds reacting with biologically relevant zinc fingers (ZnFs). Gold L 3 -edge XAS probed the interaction of gold and the C-terminal Cys 2 HisCys finger of the HIV-1 nucleocapsid protein NCp7, and the Cys 2 His 2 human transcription factor Sp1. The use of model compounds helped assign oxidation states and the identity of the gold-bound ligands. The computational studies accurately reproduced the experimental XAS spectra and allowed the proposition of structural models for the interaction products at early time points. The direct electrophilic attack on the ZnF by the highly thiophilic Au(I) resulted in a linear P-Au-Cys coordination sphere after zinc ejection whereas for the Sp1, loss of PEt 3 results in linear Cys-Au-Cys or Cys-Au-His arrangements. Reactions with Au(III) compounds, on the other hand, showed multiple binding modes. Prompt reaction between [AuCl(dien)] 2+ and [Au(dien)(DMAP)] 3+ with Sp1 showed a partially reduced Au center and a final linear His-Au-His coordination. Differently, in the presence of NCp7, [AuCl(dien)] 2+ readily reduces to Au(I) and changes from square-planar to linear geometry with Cys-Au-His coordination, while [Au(dien)(DMAP)] 3+ initially maintains its Au(III) oxidation state and square-planar geometry and the same first coordination sphere. The latter is the first observation of a "noncovalent" interaction of a Au(III) complex with a zinc finger and confirms early hypotheses that stabilization of Au(III) occurs with N-donor ligands. Modification of the zinc coordination sphere, suggesting full or partial zinc ejection, is observed in all cases, and for [Au(dien)(DMAP)] 3+ this represents a novel mechanism for nucleocapsid inactivation. The combination of XAS and TD-DFT presents the first direct experimental observation that not only compound reactivity, but also ZnF core specificity, can be modulated on the basis of the coordination sphere of Au(III) compounds.

  1. Ad E1A 243R oncoprotein promotes association of proto-oncogene product MYC with the NuA4/Tip60 complex via the E1A N-terminal repression domain.

    PubMed

    Zhao, Ling-Jun; Loewenstein, Paul M; Green, Maurice

    2016-12-01

    The adenovirus E1A 243R oncoprotein targets TRRAP, a scaffold protein that assembles histone acetyltransferase (HAT) complexes, such as the NuA4/Tip60 complex which mediates transcriptional activity of the proto-oncogene MYC and helps determine the cancer cell phenotype. How E1A transforms cells through TRRAP remains obscure. We performed proteomic analysis with the N-terminal transcriptional repression domain of E1A 243R (E1A 1-80) and showed that E1A 1-80 interacts with TRRAP, p400, and three other members of the NuA4 complex - DMAP1, RUVBL1 and RUVBL2 - not previously shown to associate with E1A 243R. E1A 1-80 interacts with these NuA4 components and MYC through the E1A TRRAP-targeting domain. E1A 243R association with the NuA4 complex was demonstrated by co-immunoprecipitation and analysis with DMAP1, Tip60, and MYC. Significantly, E1A 243R promotes association of MYC/MAX with the NuA4/Tip60 complex, implicating the importance of the MYC/NuA4 pathway in cellular transformation by both MYC and E1A. Copyright © 2016 Elsevier Inc. All rights reserved.

  2. Serum leveis of inflammatory markers in type 2 diabetes patients with chronic periodontitis

    PubMed Central

    LONGO, Priscila Larcher; ARTESE, Hilana Paula Carillo; RABELO, Marianade Sousa; KAWAMOTO, Dione; FOZ, Adriana Moura; ROMITO, Giuseppe Alexandre; DIB, Sérgio Atala; MAYER, Marcia Pinto Alves

    2014-01-01

    Diabetes has been associated with periodontitis, but the mechanisms through which periodontal diseases affect the metabolic control remain unclear. Objective This study aimed to evaluate serum leveis of inflammatory markers, IL-8, IL-6 and monocyte chemoattractant protein 1 (MCP-1), in type 2 diabetic patients in the presence of chronic periodontitis. Material and Methods Forty two individuals were enrolled in this study and assigned to one of five groups: diabetes mellitus with inadequate glycemic control and periodontitis (DMI+P, n = 10), diabetes mellitus with adequate glycemic control and periodontitis (DMA+P, n = 10), diabetes mellitus without periodontitis (DM, n = 10), periodontitis without diabetes (P, n=6), and neither diabetes nor periodontitis (H, n = 6). Periodontal clinical examination included visible plaque index (PL), gingival bleeding index (GB), probing depth (PD), attachment level (AL) and bleeding on probing (BP). Glycemic control was evaluated by serum concentration of glycated hemoglobin (HbAlc). Inflammatory serum markers IL-8, IL-6 and (MCP-1) were measured by ELISA. Results DMI+P and DMA+P groups presented higher PD (p=0.025) and AL (p=0.003) values when compared to the P group. There were no significant differences among groups for IL-6, IL-8 and MCP-1 serum levels. Conclusions Although periodontitis was more severe in diabetic patients, the serum levels of the investigated inflammatory markers did not differ among the groups. PMID:24676580

  3. Predictors of exposure to organophosphate pesticides in schoolchildren in the Province of Talca, Chile.

    PubMed

    Muñoz-Quezada, María Teresa; Iglesias, Verónica; Lucero, Boris; Steenland, Kyle; Barr, Dana Boyd; Levy, Karen; Ryan, P Barry; Alvarado, Sergio; Concha, Carlos

    2012-10-15

    Few data exist in Latin America concerning the association between organophosphate (OP) urinary metabolites and the consumption of fruits and vegetables and other exposure risk variables in schoolchildren. We collected samples of urine from 190 Chilean children aged 6-12 years, fruits and vegetables, water and soil from schools and homes, and sociodemographic data through a questionnaire. We measured urinary dialkylphosphate (DAP) OP metabolites and OP pesticide residues in food consumed by these 190 children during two seasons: December 2010 (summer) and May 2011 (fall). We analyzed the relationship between urinary DAP concentrations and pesticide residues in food, home pesticide use, and residential location. Diethylalkylphosphates (DEAP) and dimethylalkylphosphates (DMAP) were detected in urine in 76% and 27% of the samples, respectively. Factors associated with urinary DEAP included chlorpyrifos in consumed fruits (p<0.0001), urinary creatinine (p<0.0001), rural residence (p=0.02) and age less than 9 years (p=0.004). Factors associated with urinary DMAP included the presence of phosmet residues in fruits (p<0.0001), close proximity to a farm (p=0.002), home fenitrothion use (p=0.009), and season (p<0.0001). Urinary DAP levels in Chilean school children were high compared to previously reported studies. The presence of chlorpyrifos and phosmet residues in fruits was the major factor predicting urinary DAP metabolite concentrations in children. Copyright © 2012 Elsevier Ltd. All rights reserved.

  4. Atomic layer deposition of Cu( i ) oxide films using Cu( ii ) bis(dimethylamino-2-propoxide) and water

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Avila, J. R.; Peters, A. W.; Li, Zhanyong

    2017-01-01

    To grow fIlms of Cu2O, bis-(dimethylamino-2-propoxide)Cu(II), or Cu(dmap), is used as an atomic layer deposition precursor using only water vapor as a co-reactant. Between 110 and 175 °C, a growth rate of 0.12 ± 0.02 Å per cycle was measured using an in situ quartz crystal microbalance (QCM). X-ray photoelectron spectroscopy (XPS) confirms the growth of metal– oxide films featuring Cu(I).

  5. Channeling Nanoparticles for Detection and Targeted Treatment of Breast Cancerous Lesions

    DTIC Science & Technology

    2011-10-01

    µmoles, or 16.5mg) of PEG 2000. Dimethylaminopyridine (DMAP, 0.5 molar equivalents) and 1 -Ethyl- 3 - [ 3 - dimethylaminopropyl ]carbodiimide (EDC...control number. PLEASE DO NOT RETURN YOUR FORM TO THE ABOVE ADDRESS. 1 . REPORT DATE (DD-MM-YYYY) 2. REPORT TYPE 3 . DATES COVERED (From - To) 4. TITLE...OMB control number. PLEASE DO NOT RETURN YOUR FORM TO THE ABOVE ADDRESS. 1 . REPORT DATE (DD-MM-YYYY) 14-10-2011 2. REPORT TYPE Final 3 . DATES

  6. Dynamic analysis using superelements for a large helicopter model

    NASA Technical Reports Server (NTRS)

    Patel, M. P.; Shah, L. C.

    1978-01-01

    Using superelements (substructures), modal and frequency response analysis was performed for a large model of the Advanced Attack Helicopter developed for the U.S. Army. Whiffletree concept was employed so that the residual structure along with the various superelements could be represented as beam-like structures for economical and accurate dynamic analysis. A very large DMAP alter to the rigid format was developed so that the modal analysis, the frequency response, and the strain energy in each component could be computed in the same run.

  7. Varying the Lewis base coordination of the Y2N2 core in the reduced dinitrogen complexes {[(Me3Si)2N]2(L)Y}2(μ-η2:η2-N2) (L = benzonitrile, pyridines, triphenylphosphine oxide, and trimethylamine N-oxide).

    PubMed

    Corbey, Jordan F; Farnaby, Joy H; Bates, Jefferson E; Ziller, Joseph W; Furche, Filipp; Evans, William J

    2012-07-16

    The effect of the neutral donor ligand, L, on the Ln(2)N(2) core in the (N═N)(2-) complexes, [A(2)(L)Ln](2)(μ-η(2):η(2)-N(2)) (Ln = Sc, Y, lanthanide; A = monoanion; L = neutral ligand), is unknown since all of the crystallographically characterized examples were obtained with L = tetrahydrofuran (THF). To explore variation in L, displacement reactions between {[(Me(3)Si)(2)N](2)(THF)Y}(2)(μ-η(2):η(2)-N(2)), 1, and benzonitrile, pyridine (py), 4-dimethylaminopyridine (DMAP), triphenylphosphine oxide, and trimethylamine N-oxide were investigated. THF is displaced by all of these ligands to form {[(Me(3)Si)(2)N](2)(L)Y}(2)(μ-η(2):η(2)-N(2)) complexes (L = PhCN, 2; py, 3; DMAP, 4; Ph(3)PO, 5; Me(3)NO, 6) that were fully characterized by analytical, spectroscopic, density functional theory, and X-ray crystallographic methods. The crystal structures of the Y(2)N(2) cores in 2-5 are similar to that in 1 with N-N bond distances between 1.255(3) Å and 1.274(3) Å, but X-ray analysis of the N-N distance in 6 shows it to be shorter: 1.198(3) Å.

  8. Cooperative catalysis: electron-rich Fe-H complexes and DMAP, a successful "joint venture" for ultrafast hydrogen production.

    PubMed

    Rommel, Susanne; Hettmanczyk, Lara; Klein, Johannes E M N; Plietker, Bernd

    2014-08-01

    A series of defined iron-hydrogen complexes was prepared in a straightforward one-pot approach. The structure and electronic properties of such complexes were investigated by means of quantum-chemical analysis. These new complexes were then applied in the dehydrogenative silylation of methanol. The complex (dppp)(CO)(NO)FeH showed a remarkable activity with a TOF of more than 600 000 h(-1) of pure hydrogen gas within seconds. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  9. New coumarin carboxylates having trifluoromethyl, diethylamino and morpholino terminal groups: Synthesis and mesomorphic characterisations

    NASA Astrophysics Data System (ADS)

    Srinivasa, Hosapalya Thimmaiah; Harishkumar, Hosanagara Narayana; Palakshamurthy, Bandrehalli Siddagangappa

    2017-03-01

    New set of trifluromethyl, diethylamino and morpholino derived coumarin compounds were prepared by reacting various coumarin 3-carboxylic acids with various phenyl esters with peripheral alkyl, ester and polar cyano moieties in the presence of EDC.HCl/DMAP as esterification agent. The chemical structures of new coumarin derivatives were confirmed by standard spectroscopic techniques and mesomorphic behaviours were established by polarised optical microscopy (POM) and differential scanning calorimetry (DSC). Trifluoromethane and morpholino derivatives show SmA/Nematic phase, while diethylamino derivatives did not show liquid crystalline property.

  10. 25 CFR 170.161 - What is the Indian Local Technical Assistance Program?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false What is the Indian Local Technical Assistance Program... Technical Assistance Program § 170.161 What is the Indian Local Technical Assistance Program? The Indian Local Technical Assistance Program (Indian LTAP) is authorized under 23 U.S.C. 504(b), and §§ 170.161...

  11. 75 FR 13521 - Centers for Independent Living Program-Training and Technical Assistance

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-22

    ... DEPARTMENT OF EDUCATION Centers for Independent Living Program--Training and Technical Assistance... for Independent Living Program--Training and Technical Assistance (CIL-TA program). The Assistant... appropriated for the CIL program to provide training and technical assistance to CILs, agencies eligible to...

  12. An Improved System for Generation of Diploid Cloned Porcine Embryos Using Induced Pluripotent Stem Cells Synchronized to Metaphase.

    PubMed

    Kim, Eunhye; Zheng, Zhong; Jeon, Yubyeol; Jin, Yong-Xun; Hwang, Seon-Ung; Cai, Lian; Lee, Chang-Kyu; Kim, Nam-Hyung; Hyun, Sang-Hwan

    2016-01-01

    Pigs provide outstanding models of human genetic diseases due to their striking similarities with human anatomy, physiology and genetics. Although transgenic pigs have been produced using genetically modified somatic cells and nuclear transfer (SCNT), the cloning efficiency was extremely low. Here, we report an improved method to produce diploid cloned embryos from porcine induced pluripotent stem cells (piPSCs), which were synchronized to the G2/M stage using a double blocking method with aphidicolin and nocodazole. The efficiency of this synchronization method on our piPSC lines was first tested. Then, we modified our traditional SCNT protocol to find a workable protocol. In particular, the removal of a 6DMAP treatment post-activation enhanced the extrusion rate of pseudo-second-polar bodies (p2PB) (81.3% vs. 15.8%, based on peak time, 4hpa). Moreover, an immediate activation method yielded significantly more blastocysts than delayed activation (31.3% vs. 16.0%, based on fused embryos). The immunofluorescent results confirmed the effect of the 6DMAP treatment removal, showing remarkable p2PB extrusion during a series of nuclear transfer procedures. The reconstructed embryos from metaphase piPSCs with our modified protocol demonstrated normal morphology at 2-cell, 4-cell and blastocyst stages and a high rate of normal karyotype. This study demonstrated a new and efficient way to produce viable cloned embryos from piPSCs when synchronized to the G2/M phase of the cell cycle, which may lead to opportunities to produce cloned pigs from piPSCs more efficiently.

  13. The Technical Assistance Program: A Program Plan.

    DTIC Science & Technology

    1985-09-01

    interests, talents, and hobbies of current employees who wish to become involved in the technical assistance program . 4. Capitalize on the corporate...Center San Diego, CA 92152 Telephone (619) 225-6281 B-33 TAP ( EMPLOYEE ) QUESTIONNAIRE - The Technical Assistance Program (TAP) links technically skilled...Brochure, "Retired Technologist" C-11 C. Sample Letter to NOSC Employees C-13 Brochure D. The Technical Assistance Program C-15 C-1

  14. What You Should Get from a Professionally Oriented Master's Degree Program in Technical Communication.

    ERIC Educational Resources Information Center

    Carliner, Saul

    1992-01-01

    Cites reasons for pursuing a curriculum in technical communication, lists objectives a program should achieve, and outlines a four-part program that includes theory, professional skills, technical proficiency, and an internship. Lists schools offering programs in technical communication. (SR)

  15. Alkylating Derivatives of Vitamin D Hormone for Prostate Cancer

    DTIC Science & Technology

    2006-10-01

    Acetic Anhydride / Pyridine/ 40C 1. UV / Toluene 2. EtOH - Reflux TBDMSCl / Imidazole /DMF BrCH2COOH / DCC / DMAP / CH2Cl2 1,25(OH)2D3-3-BE Figure 1...BE OH SO2 OTBDMS OH OTBDMS 1. Liq. SO2 / Reflux 2. TBDMSCl / Imidazole /DMF NaHCO3 / EtOH / Reflux NMO / SeO2 / CH2Cl2 / Reflux OH OTBDMSHO OTHP...containing 200 mg of 25-hydroxyvitamin D3 in a flask fitted with a trap that was cooled with dry ice-acetone (-780C). The yellow solution was refluxed

  16. 78 FR 13030 - Applications for New Awards; Native American Career and Technical Education Program (NACTEP)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-26

    ... DEPARTMENT OF EDUCATION Applications for New Awards; Native American Career and Technical...: Notice. Overview Information: Native American Career and Technical Education Program (NACTEP). Notice... Purpose of Program: The Native American Career and Technical Education Program (NACTEP) provides grants to...

  17. Comprehensive Forced Response Analysis of J2X Turbine Bladed-Discs with 36- Degree Variation in CFD Loading

    NASA Technical Reports Server (NTRS)

    Elrod, David; Christensen, Eric; Brown, Andrew

    2011-01-01

    At NASA/MSFC, Structural Dynamics personnel continue to perform advanced analysis for the turbomachinery in the J2X Rocket Engine, which is under consideration for the new Space Launch System. One of the most challenging analyses in the program is predicting turbine blade structural capability. Resonance was predicted by modal analysis, so comprehensive forced response analyses using high fidelity cyclic symmetric finite element models were initiated as required. Analysis methodologies up to this point have assumed the flow field could be fully described by a sector, so the loading on every blade would be identical as it travelled through it. However, in the J2X the CFD flow field varied over the 360 deg of a revolution because of the flow speeds and tortuous axial path. MSFC therefore developed a complex procedure using Nastran Dmap's and Matlab scripts to apply this circumferentially varying loading onto the cyclically symmetric structural models to produce accurate dynamic stresses for every blade on the disk. This procedure is coupled with static, spin, and thermal loading to produce high cycle fatigue safety factors resulting in much more accurate analytical assessments of the blades.

  18. 75 FR 29732 - Career and Technical Education Program-Promoting Rigorous Career and Technical Education Programs...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-27

    ... DEPARTMENT OF EDUCATION Career and Technical Education Program--Promoting Rigorous Career and Technical Education Programs of Study Catalog of Federal Domestic Assistance (CFDA) Number: 84.051C. AGENCY: Office of Vocational and Adult Education, Department of Education. ACTION: Notice of proposed priorities...

  19. The synthesis, structure and properties of N-acetylated derivatives of ethyl 3-amino-1H-pyrazole-4-carboxylate.

    PubMed

    Kusakiewicz-Dawid, Anna; Masiukiewicz, Elzbieta; Rzeszotarska, Barbara; Dybała, Izabela; Kozioł, Anna Eugenia; Broda, Małgorzata Anna

    2007-05-01

    Ethyl 3-amino-1H-pyrazole-4-carboxylate (1) was yielded through total synthesis and reacted with acetic anhydride to give the acetylated products 2-6. Compounds 1-6 were studied with HPLC, X-ray, FT-IR, (1)H-NMR, (13)C-NMR and MS. Acetylation was carried out in solvents of various polarity, namely; chloroform; dioxane; DMF; acetic anhydride, at room temperature and at boiling points; and in the presence and absence of DMAP. The acetylated products are mainly nitrogen atoms in the ring. The position of the ring proton in the solution was based on NOESY; multinuclear HMBC, HSQC spectra and calculations. For equivalent amounts (1-1.5 mol) of acetic anhydride at room temperature two products of monoacetylation are produced in the ring: 2 and 3, ca. 2 : 1 and at the same time only small amount of the third product of monoacetylated, 5 in DMF, as well the product diacetylated, 4. The greatest amount of the product 4 is produced during the reaction with chloroform. However, in this solvent and in dioxane no product 5 is produced. Compound 2 is, largely, formed in dimethylformamide, in the presence DMAP, 0.2 eq. In the presence of this catalytic base, for the first hour, there is a mixture 2 and 3 to the ratio ca. 95 : 5. With 8 eq of Ac(2)O at reflux, after another hour, the compounds 3, 4 and 6 appear about equal amounts. After a longer time, the compound, which appears most in this mixture is triacetylated derivative 6. The structural and spectroscopic characteristics of compounds 1-6 have been given and the methods for their preparation have been provided.

  20. Generalized seismic analysis

    NASA Technical Reports Server (NTRS)

    Butler, Thomas G.

    1993-01-01

    There is a constant need to be able to solve for enforced motion of structures. Spacecraft need to be qualified for acceleration inputs. Truck cargoes need to be safeguarded from road mishaps. Office buildings need to withstand earthquake shocks. Marine machinery needs to be able to withstand hull shocks. All of these kinds of enforced motions are being grouped together under the heading of seismic inputs. Attempts have been made to cope with this problem over the years and they usually have ended up with some limiting or compromise conditions. The crudest approach was to limit the problem to acceleration occurring only at a base of a structure, constrained to be rigid. The analyst would assign arbitrarily outsized masses to base points. He would then calculate the magnitude of force to apply to the base mass (or masses) in order to produce the specified acceleration. He would of necessity have to sacrifice the determination of stresses in the vicinity of the base, because of the artificial nature of the input forces. The author followed the lead of John M. Biggs by using relative coordinates for a rigid base in a 1975 paper, and again in a 1981 paper . This method of relative coordinates was extended and made operational as DMAP ALTER packets to rigid formats 9, 10, 11, and 12 under contract N60921-82-C-0128. This method was presented at the twelfth NASTRAN Colloquium. Another analyst in the field developed a method that computed the forces from enforced motion then applied them as a forcing to the remaining unknowns after the knowns were partitioned off. The method was translated into DMAP ALTER's but was never made operational. All of this activity jelled into the current effort. Much thought was invested in working out ways to unshakle the analysis of enforced motions from the limitations that persisted.

  1. Generalized seismic analysis

    NASA Astrophysics Data System (ADS)

    Butler, Thomas G.

    1993-09-01

    There is a constant need to be able to solve for enforced motion of structures. Spacecraft need to be qualified for acceleration inputs. Truck cargoes need to be safeguarded from road mishaps. Office buildings need to withstand earthquake shocks. Marine machinery needs to be able to withstand hull shocks. All of these kinds of enforced motions are being grouped together under the heading of seismic inputs. Attempts have been made to cope with this problem over the years and they usually have ended up with some limiting or compromise conditions. The crudest approach was to limit the problem to acceleration occurring only at a base of a structure, constrained to be rigid. The analyst would assign arbitrarily outsized masses to base points. He would then calculate the magnitude of force to apply to the base mass (or masses) in order to produce the specified acceleration. He would of necessity have to sacrifice the determination of stresses in the vicinity of the base, because of the artificial nature of the input forces. The author followed the lead of John M. Biggs by using relative coordinates for a rigid base in a 1975 paper, and again in a 1981 paper . This method of relative coordinates was extended and made operational as DMAP ALTER packets to rigid formats 9, 10, 11, and 12 under contract N60921-82-C-0128. This method was presented at the twelfth NASTRAN Colloquium. Another analyst in the field developed a method that computed the forces from enforced motion then applied them as a forcing to the remaining unknowns after the knowns were partitioned off. The method was translated into DMAP ALTER's but was never made operational. All of this activity jelled into the current effort. Much thought was invested in working out ways to unshakle the analysis of enforced motions from the limitations that persisted.

  2. Electrophysiological, haemodynamic, and mitochondrial alterations induced by levobupivacaine during myocardial ischemia in a pig model: protection by lipid emulsions?

    PubMed

    Mamou, Zahida; Descotes, Jacques; Chevalier, Philippe; Bui-Xuan, Bernard; Romestaing, Caroline; Timour, Quadiri

    2015-10-01

    Accidental intravascular or high-dose injection of local anesthetics (LA) can result in serious, potentially life-threatening complications. Indeed, adequate supportive measures and the administration of lipid emulsions are required in such complications. The study's objectives were threefold: (i) evaluate the myocardial toxicity of levobupivacaine when administered intravenously; (ii) investigate levobupivacaine toxicity on cardiomyocytes mitochondrial functions and cellular structure; (iii) assess the protective effects of a lipid emulsion in the presence or absence of myocardial ischemia. Domestic pigs randomized into two groups of 24 animals each, with either preserved coronary circulation or experimental myocardial ischemia. Six animals from each group received either: (i) single IV injection of saline, (ii) lipid emulsion (Intralipid(®) ), (iii) levobupivacaine, (iv) combination levobupivacaine-Intralipid(®) . Serially measured endpoints included: heart rate, duration of the monophasic action potentials (dMAP), mean arterial pressure, and peak of the time derivative of left ventricular pressure (LV dP/dtmax ). In addition, the following cardiomyocytes mitochondrial functions were measured: reactive oxygen species (ROS) production, oxidative phosphorylation, and calcium retention capacity (CRC) as well as the consequences of ROS production on lipids, proteins, and DNA. IV injection of levobupivacaine induced sinus bradycardia and reduced dMAP and LV dP/dtmax . At the mitochondrial level, oxygen consumption and CRC were decreased. In contrast, ROS production was increased leading to enhanced lipid peroxidation and structural alterations of proteins and DNA. Myocardial ischemia was associated with global worsening of all changes. Intralipid(®) quickly improved haemodynamics. However, beneficial effects of Intralipid(®) were less clear after myocardial ischemia. © 2015 Société Française de Pharmacologie et de Thérapeutique.

  3. MAP Reconstruction for Fourier Rebinned TOF-PET Data

    PubMed Central

    Bai, Bing; Lin, Yanguang; Zhu, Wentao; Ren, Ran; Li, Quanzheng; Dahlbom, Magnus; DiFilippo, Frank; Leahy, Richard M.

    2014-01-01

    Time-of-flight (TOF) information improves signal to noise ratio in Positron Emission Tomography (PET). Computation cost in processing TOF-PET sinograms is substantially higher than for nonTOF data because the data in each line of response is divided among multiple time of flight bins. This additional cost has motivated research into methods for rebinning TOF data into lower dimensional representations that exploit redundancies inherent in TOF data. We have previously developed approximate Fourier methods that rebin TOF data into either 3D nonTOF or 2D nonTOF formats. We refer to these methods respectively as FORET-3D and FORET-2D. Here we describe maximum a posteriori (MAP) estimators for use with FORET rebinned data. We first derive approximate expressions for the variance of the rebinned data. We then use these results to rescale the data so that the variance and mean are approximately equal allowing us to use the Poisson likelihood model for MAP reconstruction. MAP reconstruction from these rebinned data uses a system matrix in which the detector response model accounts for the effects of rebinning. Using these methods we compare performance of FORET-2D and 3D with TOF and nonTOF reconstructions using phantom and clinical data. Our phantom results show a small loss in contrast recovery at matched noise levels using FORET compared to reconstruction from the original TOF data. Clinical examples show FORET images that are qualitatively similar to those obtained from the original TOF-PET data but a small increase in variance at matched resolution. Reconstruction time is reduced by a factor of 5 and 30 using FORET3D+MAP and FORET2D+MAP respectively compared to 3D TOF MAP, which makes these methods attractive for clinical applications. PMID:24504374

  4. MDGA2 is a novel tumour suppressor cooperating with DMAP1 in gastric cancer and is associated with disease outcome

    PubMed Central

    Wang, Kunning; Liang, Qiaoyi; Li, Xiaoxing; Tsoi, Ho; Zhang, Jingwan; Wang, Hua; Go, Minnie Y Y; Chiu, Philip W Y; Ng, Enders K W; Sung, Joseph J Y; Yu, Jun

    2016-01-01

    Background Using the promoter methylation assay, we have shown that MDGA2 (MAM domain containing glycosylphosphatidylinositol anchor 2) is preferentially methylated in gastric cancer. We analysed its biological effects and prognostic significance in gastric cancer. Methods MDGA2 methylation status was evaluated by combined bisulfite restriction analysis and bisulfite genomic sequencing. The effects of MDGA2 re-expression or knockdown on cell proliferation, apoptosis and the cell cycle were determined. MDGA2 interacting protein was identified by mass spectrometry and MDGA2-related cancer pathways by reporter activity and PCR array analyses. The clinical impact of MDGA2 was assessed in 218 patients with gastric cancer. Results MDGA2 was commonly silenced in gastric cancer cells (10/11) and primary gastric cancers due to promoter hypermethylation. MDGA2 significantly inhibited cell proliferation by causing G1–S cell cycle arrest and inducing cell apoptosis in vitro, and suppressed xenograft tumour growth in both subcutaneous and orthotopic xenograft mouse models (both p<0.001). The anti-tumorigenic effect of MDGA2 was mediated through direct stabilising of DNA methyltransferase 1 associated protein 1 (DMAP1), which played a tumour suppressive role in gastric cancer. This interaction activated their downstream key elements of p53/p21 signalling cascades. Moreover, promoter methylation of MDGA2 was detected in 62.4% (136/218) of gastric cancers. Multivariate analysis showed that patients with MDGA2 hypermethylation had a significantly decreased survival (p=0.005). Kaplan–Meier survival curves showed that MDGA2 hypermethylation was significantly associated with shortened survival in patients with early gastric cancer. Conclusions MDGA2 is a critical tumour suppressor in gastric carcinogenesis; its hypermethylation is an independent prognostic factor in patients with gastric cancer. PMID:26206665

  5. Development of NASA Technical Standards Program Relative to Enhancing Engineering Capabilities

    NASA Technical Reports Server (NTRS)

    Gill, Paul S.; Vaughan, William W.

    2003-01-01

    The enhancement of engineering capabilities is an important aspect of any organization; especially those engaged in aerospace development activities. Technical Standards are one of the key elements of this endeavor. The NASA Technical Standards Program was formed in 1997 in response to the NASA Administrator s directive to develop an Agencywide Technical Standards Program. The Program s principal objective involved the converting Center-unique technical standards into Agency wide standards and the adoption/endorsement of non-Government technical standards in lieu of government standards. In the process of these actions, the potential for further enhancement of the Agency s engineering capabilities was noted relative to value of being able to access Agencywide the necessary full-text technical standards, standards update notifications, and integration of lessons learned with technical standards, all available to the user from one Website. This was accomplished and is now being enhanced based on feedbacks from the Agency's engineering staff and supporting contractors. This paper addresses the development experiences with the NASA Technical Standards Program and the enhancement of the Agency's engineering capabilities provided by the Program s products. Metrics are provided on significant aspects of the Program.

  6. 10 CFR 455.122 - Applicant certifications for State grants for technical assistance, program assistance, and...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... assistance, program assistance, and marketing. 455.122 Section 455.122 Energy DEPARTMENT OF ENERGY ENERGY... for State grants for technical assistance, program assistance, and marketing. Applications from States for financial assistance for technical assistance programs, program assistance, and marketing shall...

  7. 13 CFR 124.701 - What is the purpose of the 7(j) management and technical assistance program?

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...) management and technical assistance program? 124.701 Section 124.701 Business Credit and Assistance SMALL...) Business Development Management and Technical Assistance Program § 124.701 What is the purpose of the 7(j) management and technical assistance program? Section 7(j)(1) of the Small Business Act, 15 U.S.C. 636(j)(1...

  8. Technical Skill Attainment and Post-Program Outcomes: An Analysis of Pennsylvania Secondary Career and Technical Education Graduates

    ERIC Educational Resources Information Center

    Staklis, Sandra; Klein, Steven

    2010-01-01

    Since the mid-1990s, the Pennsylvania Department of Education (PDE) has required all students concentrating in career and technical education (CTE) programs to complete a standardized technical skill assessment at or near the end of their program. Results of technical skill assessments are used for a number of purposes, including recognizing…

  9. DOE standard: The Department of Energy Laboratory Accreditation Program for radiobioassay

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    1998-12-01

    This technical standard describes the US Department of Energy Laboratory Accreditation Program (DOELAP) for Radiobioassay, for use by the US Department of Energy (DOE) and DOE Contractor radiobioassay programs. This standard is intended to be used in conjunction with the general administrative technical standard that describes the overall DOELAP accreditation process--DOE-STD-1111-98, Department of Energy Laboratory Accreditation Program Administration. This technical standard pertains to radiobioassay service laboratories that provide either direct or indirect (in vivo or in vitro) radiobioassay measurements in support of internal dosimetry programs at DOE facilities or for DOE and DOE contractors. Similar technical standards have been developedmore » for other DOELAP dosimetry programs. This program consists of providing an accreditation to DOE radiobioassay programs based on successful completion of a performance-testing process and an on-site evaluation by technical experts. This standard describes the technical requirements and processes specific to the DOELAP Radiobioassay Accreditation Program as required by 10 CFR 835 and as specified generically in DOE-STD-1111-98.« less

  10. 76 FR 35474 - UAW-Chrysler Technical Training Center, Technology Training Joint Programs Staff, Including On...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-17

    ...-Chrysler Technical Training Center, Technology Training Joint Programs Staff, Including On-Site Leased Workers From Cranks, O/E Learning, DBSI, IDEA, and Tonic/MVP, Detroit, MI; UAW-Chrysler Technical Training... workers and former workers of UAW-Chrysler Technical Training Center, Technology Training Joint Programs...

  11. The Secretary's Awards for Outstanding Vocational-Technical Education Programs. 1995.

    ERIC Educational Resources Information Center

    Office of Vocational and Adult Education (ED), Washington, DC.

    This publication describes the 12 winning programs and the 9 semifinalists of the 1995 U.S. Secretary of Education's Awards for Outstanding Vocational-Technical Education Programs. The awards program was established in 1981 to recognize excellence in local school-to-work and vocational-technical education programs, services, and activities that…

  12. 75 FR 29366 - ``Homeless Veterans' Reintegration Program (HVRP) National Technical Assistance Center...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-25

    ... ``Homeless Veterans' Reintegration Program (HVRP) National Technical Assistance Center Cooperative Agreement...). Section 2021 authorizes programs to expedite the reintegration of homeless Veterans into the labor force... Technical Assistance Center (NTAC) for the Homeless Veterans' Reintegration Program (HVRP) to include the...

  13. 78 FR 25292 - Announcement of Funding Awards; Office of Native American Programs Training and Technical...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-30

    ... Awards; Office of Native American Programs Training and Technical Assistance; Fiscal Year 2012 AGENCY... (NOFA) for the Office of Native American Programs Training and Technical Assistance (ONAP T&TA). This... nonprofit organizations, as well as for-profit entities to provide Training & Technical Assistance to the...

  14. Low Cost Technical Solutions to Jump Start an Insider Threat Program

    DTIC Science & Technology

    2016-05-11

    Low Cost Technical Solutions to Jump Start an Insider Threat Program George J. Silowash Derrick L. Spooner Daniel L. Costa Michael J...Albrethsen May 2016 TECHNICAL NOTE CMU/SEI-2016-TN-004 CERT Division http://www.sei.cmu.edu Copyright 2016 Carnegie Mellon University This... technical note will explore tools that may be suitable for satisfying the basic technical needs of an insider threat program, giving organizations a

  15. Owning the program technical baseline for future space systems acquisition: program technical baseline tracking tool

    NASA Astrophysics Data System (ADS)

    Nguyen, Tien M.; Guillen, Andy T.; Hant, James J.; Kizer, Justin R.; Min, Inki A.; Siedlak, Dennis J. L.; Yoh, James

    2017-05-01

    The U.S. Air Force (USAF) has recognized the needs for owning the program and technical knowledge within the Air Force concerning the systems being acquired to ensure success. This paper extends the previous work done by the authors [1-2] on the "Resilient Program Technical Baseline Framework for Future Space Systems" and "Portfolio Decision Support Tool (PDST)" to the development and implementation of the Program and Technical Baseline (PTB) Tracking Tool (PTBTL) for the DOD acquisition life cycle. The paper describes the "simplified" PTB tracking model with a focus on the preaward phases and discusses how to implement this model in PDST.

  16. NASA Technical Standards Program

    NASA Technical Reports Server (NTRS)

    Gill, Paul S.; Vaughan, William W.; Parker, Nelson C. (Technical Monitor)

    2002-01-01

    The NASA Technical Standards Program was officially established in 1997 as result of a directive issued by the Administrator. It is responsible for Agency wide technical standards development, adoption (endorsement), and conversion of Center-unique standards for Agency wide use. One major element of the Program is the review of NSA technical standards products and replacement with non-Government Voluntary Consensus Standards in accordance with directions issued by the Office of Management and Budget. As part of the Program's function, it developed a NASA Integrated Technical Standards Initiative that consists of and Agency wide full-text system, standards update notification system, and lessons learned-standards integration system. The Program maintains a 'one stop-shop' Website for technical standards ad related information on aerospace materials, etc. This paper provides information on the development, current status, and plans for the NAS Technical Standards Program along with metrics on the utility of the products provided to both users within the nasa.gov Domain and the Public Domain.

  17. NASA Technical Standards Program

    NASA Technical Reports Server (NTRS)

    Gill, Paul S.; Vaughan, WIlliam W.

    2003-01-01

    The NASA Technical Standards Program was officially established in 1997 as result of a directive issued by the Administrator. It is responsible for Agency wide technical standards development, adoption (endorsement), and conversion of Center-unique standards for Agency wide use. One major element of the Program is the review of NSA technical standards products and replacement with non-Government Voluntary Consensus Standards in accordance with directions issued by the Office of Management and Budget. As part of the Program s function, it developed a NASA Integrated Technical Standards Initiative that consists of and Agency wide full-text system, standards update notification system, and lessons learned - standards integration system. The Program maintains a "one stop-shop" Website for technical standards ad related information on aerospace materials, etc. This paper provides information on the development, current status, and plans for the NAS Technical Standards Program along with metrics on the utility of the products provided to both users within the nasa.gov Domain and the Public Domain.

  18. Middlesex Community College Software Technical Writing Program.

    ERIC Educational Resources Information Center

    Middlesex Community Coll., Bedford, MA.

    This document describes the Software Technical Writing Program at Middlesex Community College (Massachusetts). The program is a "hands-on" course designed to develop job-related skills in three major areas: technical writing, software, and professional skills. The program was originally designed in cooperation with the Massachusetts High…

  19. Technical Assistance and Changes in Nutrition and Physical Activity Practices in the National Early Care and Education Learning Collaboratives Project, 2015-2016.

    PubMed

    Chiappone, Alethea; Smith, Teresa M; Estabrooks, Paul A; Rasmussen, Cristy Geno; Blaser, Casey; Yaroch, Amy L

    2018-04-26

    The National Early Care and Education Learning Collaboratives Project (ECELC) aims to improve best practices in early care and education (ECE) programs in topic areas of the Nutrition and Physical Activity Self-Assessment in Child Care (NAP SACC). Technical assistance is a component of the ECELC, yet its effect on outcomes is unclear. Beyond dose and duration of technical assistance, limited research exists on characteristics of technical assistance that contribute to outcomes. The objective of this study was to identify and describe technical assistance characteristics and explore associations with NAP SACC outcomes. We collected data from 10 collaboratives comprising 84 ECE programs in 2 states in 2015-2016. The objective of technical assistance was to support programs in improving best practices. Technical assistance was provided to programs via on-site, telephone, or email and was tailored to program needs. We used a mixed-methods design to examine associations between technical assistance and NAP SACC outcomes. We used multiple regression analysis to assess quantitative data and qualitative comparative analysis to determine necessary and sufficient technical assistance conditions supporting NAP SACC outcomes. We also conducted a document review to describe technical assistance that referred conditions identified by the qualitative comparative analysis. Regression analyses detected an inverse relationship between changes in NAP SACC scores and hours of technical assistance. No clear pattern emerged in the qualitative comparative analysis, leaving no necessary and sufficient conditions. However, the qualitative comparative analysis identified feedback as a potentially important component of technical assistance, whereas resource sharing and frequent email were characteristics that seemed to reduce the likelihood of improved outcomes. Email and resource sharing were considered primarily general information rather than tailored technical assistance. Technical assistance may be used in programs and made adaptable to program needs. The inclusion and evaluation of technical assistance, especially tailored approaches, is warranted for environmental interventions, including ECE settings.

  20. Guidelines for Establishing and Evaluating High School Technical Electromechanics Programs.

    ERIC Educational Resources Information Center

    Florida State Dept. of Education, Tallahassee. Div. of Vocational, Technical and Adult Education.

    Educators and industrial representatives developed these guidelines for school officials, instructors in technical education, and program and facility planners to use in planning a high school program in technical electromechanics. Designed to train students for entry into industry in applied electromechanics, the program includes electricity,…

  1. Technical Preparation: Preparing Students for Success. A Position Paper Presented by the Wisconsin Association of Secondary Vocational Administrators 1991-1992.

    ERIC Educational Resources Information Center

    Peterson, Charlene; And Others

    Technical Preparation (Tech Prep) programs include basic skills and competencies to improve students' school-to-work transition. The following elements characterize Tech Prep: designed for grades 9-14, leading to an technical associate degree; parallels college preparatory program; offers technical program of study in business enterprise,…

  2. Leveraging Independent Management and Chief Engineer Hierarchy: Vertically and Horizontally-Derived Technical Authority Value

    NASA Technical Reports Server (NTRS)

    Barley, Bryan; Newhouse, Marilyn

    2012-01-01

    In the development of complex spacecraft missions, project management authority is usually extended hierarchically from NASA's highest agency levels down to the implementing institution's project team level, through both the center and the program. In parallel with management authority, NASA utilizes a complementary, but independent, hierarchy of technical authority (TA) that extends from the agency level to the project, again, through both the center and the program. The chief engineers (CEs) who serve in this technical authority capacity oversee and report on the technical status and ensure sound engineering practices, controls, and management of the projects and programs. At the lowest level, implementing institutions assign project CEs to technically engage projects, lead development teams, and ensure sound technical principles, processes, and issue resolution. At the middle level, programs and centers independently use CEs to ensure the technical success of their projects and programs. At the agency level, NASA's mission directorate CEs maintain technical cognizance over every program and project in their directorate and advise directorate management on the technical, cost, schedule, and programmatic health of each. As part of this vertically-extended CE team, a program level CE manages a continually varying balance between penetration depth and breadth across his or her assigned missions. Teamwork issues and information integration become critical for management at all levels to ensure value-added use of both the synergy available between CEs at the various agency levels, and the independence of the technical authority at each organization.

  3. Defense Technical Information Center (DTIC) - Its role in the USAF Scientific and Technical Information Program

    NASA Technical Reports Server (NTRS)

    Kuhn, Allan D.

    1991-01-01

    The Defense Technical Information Center (DTIC), the central repository for DOD scientific and technical information concerning studies and research and engineering efforts, is discussed. The present makeup of DTIC is described and its functions in producing technical reports and technical report bibliographies are examined. DTIC's outreach services are reviewed, as are its DTIC information and technology transfer programs. DTIC's plans for the year 2000 and its relation to the mission of the U.S. Air Force, including the Air Force's STINFO program, are addressed.

  4. 77 FR 37710 - Notice of Proposed Information Collection

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-22

    ... to continue the collection of information for two technical training program course effectiveness... approval. This collection is for OSM's Technical Training Program Course Effectiveness Evaluations (1029... collection activity: Title: Technical Training Program Course Effectiveness Evaluation. OMB Control Number...

  5. NOAAPORT User's Page

    Science.gov Websites

    Update History NOAAPORT Technical Contacts NOAAPORT Program Overview NOAAPORT Reference Documentation NOAAPORT Update History - for the NOAAPORT Program. NOAAPORT Technical Contacts - NWS Technical Points of Alignment Information. Receiver Characteristics - Technical Characteristics of the NOAAPORT Receiver. Data

  6. 76 FR 18624 - Research, Technical Assistance and Training Programs: Notice of Final Circular

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-04

    ... to FTA Circular 6100.1D, Research and Technical Assistance Training Program: Application Instructions... DEPARTMENT OF TRANSPORTATION Federal Transit Administration Research, Technical Assistance and Training Programs: Notice of Final Circular AGENCY: Federal Transit Administration (FTA), DOT. ACTION...

  7. 10 CFR 455.131 - State ranking of grant applications.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...) For technical assistance programs, buildings shall be ranked in descending priority based upon the... all buildings covered by eligible applications for: (1) Technical assistance programs for units of local government and public care institutions and (2) Technical assistance programs for schools and...

  8. On-line Naval Engineering Skills Supplemental Training Program

    DTIC Science & Technology

    2010-01-01

    Defense Technical University ( DTU ), the technical content for courses would have to be provided by the Naval technical authorities...of technological knowledge related to design engineering such as the DTU , or expanded within the mission scope of an existing organization such as...management program as a training tool for naval design engineers such as the DTU or a technical extension of the DAU program for acquisition training

  9. Technical Assistance and Changes in Nutrition and Physical Activity Practices in the National Early Care and Education Learning Collaboratives Project, 2015–2016

    PubMed Central

    Smith, Teresa M.; Estabrooks, Paul A.; Rasmussen, Cristy Geno; Blaser, Casey; Yaroch, Amy L

    2018-01-01

    Purpose and Objectives The National Early Care and Education Learning Collaboratives Project (ECELC) aims to improve best practices in early care and education (ECE) programs in topic areas of the Nutrition and Physical Activity Self-Assessment in Child Care (NAP SACC). Technical assistance is a component of the ECELC, yet its effect on outcomes is unclear. Beyond dose and duration of technical assistance, limited research exists on characteristics of technical assistance that contribute to outcomes. The objective of this study was to identify and describe technical assistance characteristics and explore associations with NAP SACC outcomes. Intervention Approach We collected data from 10 collaboratives comprising 84 ECE programs in 2 states in 2015–2016. The objective of technical assistance was to support programs in improving best practices. Technical assistance was provided to programs via on-site, telephone, or email and was tailored to program needs. Evaluation Methods We used a mixed-methods design to examine associations between technical assistance and NAP SACC outcomes. We used multiple regression analysis to assess quantitative data and qualitative comparative analysis to determine necessary and sufficient technical assistance conditions supporting NAP SACC outcomes. We also conducted a document review to describe technical assistance that referred conditions identified by the qualitative comparative analysis. Results Regression analyses detected an inverse relationship between changes in NAP SACC scores and hours of technical assistance. No clear pattern emerged in the qualitative comparative analysis, leaving no necessary and sufficient conditions. However, the qualitative comparative analysis identified feedback as a potentially important component of technical assistance, whereas resource sharing and frequent email were characteristics that seemed to reduce the likelihood of improved outcomes. Email and resource sharing were considered primarily general information rather than tailored technical assistance. Implications for Public Health Technical assistance may be used in programs and made adaptable to program needs. The inclusion and evaluation of technical assistance, especially tailored approaches, is warranted for environmental interventions, including ECE settings. PMID:29704371

  10. Technical assistance for hazardous-waste reduction

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Thompson, F.M.; McComas, C.A.

    1987-12-01

    Minnesota's Waste Management Board has established, developed, and funded the Minnesota Technical Assistance Program (MnTAP). The MnTAP programs offers technical assistance to generators of hazardous waste by offering telephone and onsite consultation, a waste reduction resource bank, information dissemination, a student intern program, and research awards for waste reduction projects. The program has completed three years of successful operation. The increasing interest in and use of MnTAP's services by hazardous-waste generators has justified the belief that state technical assistance programs have an important role to play in helping generators to reduce their waste production.

  11. 15 CFR 296.32 - Technical and educational services.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Technical and educational services... NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY, DEPARTMENT OF COMMERCE NIST EXTRAMURAL PROGRAMS TECHNOLOGY INNOVATION PROGRAM Dissemination of Program Results § 296.32 Technical and educational services. (a) Under...

  12. 40 CFR 52.1110 - Small business stationary source technical and environmental compliance assistance program.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... technical and environmental compliance assistance program. 52.1110 Section 52.1110 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Maryland § 52.1110 Small business stationary source technical and environmental...

  13. 76 FR 14372 - New Mexico Collaborative Forest Restoration Program Technical Advisory Panel

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-16

    ... DEPARTMENT OF AGRICULTURE Forest Service New Mexico Collaborative Forest Restoration Program Technical Advisory Panel AGENCY: Forest Service, USDA. ACTION: Notice of meeting. SUMMARY: The New Mexico Collaborative Forest Restoration Program Technical Advisory Panel will meet in Albuquerque, New Mexico. The...

  14. 48 CFR 242.7400 - General.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Contractor Facilities 242.7400 General. (a) Program managers may conclude that they need technical... manager may assign technical representatives under the procedures in 242.7401. (b) A technical representative is a representative of a DoD program, project, or system office performing non-CAS technical...

  15. 48 CFR 242.7400 - General.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Contractor Facilities 242.7400 General. (a) Program managers may conclude that they need technical... manager may assign technical representatives under the procedures in 242.7401. (b) A technical representative is a representative of a DoD program, project, or system office performing non-CAS technical...

  16. Novel Hybrid Molecules on the Basis of Steroids and (5Z,9Z)-Tetradeca-5,9-dienoic Acid: Synthesis, Anti-Cancer Studies and Human Topoisomerase I Inhibitory Activity.

    PubMed

    D'yakonov, Vladimir A; Dzhemileva, Lilya U; Tuktarova, Regina A; Ishmukhametova, Svetlana R; Yunusbaeva, Milyausha M; Ramazanova, Ilfir R; Dzhemilev, Usein M

    2017-01-01

    Novel steroid derivatives of 5Z,9Z-dienoic acids were prepared by the DCC/DMAP-catalyzed esterification of (5Z,9Z)-tetradeca-5,9-dienoic acid with hydroxy steroids. High cytotoxicity towards the HEK293, Jurkat, K562 cancer cell lines and human topoisomerase I (hTop1) inhibitory activity in vitro were found for the synthesized acids. A probable mechanism of topoisomerase I inhibition was hypothesized on the basis of in silico studies resorting to docking. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

  17. Numerical solution of Euler's equation by perturbed functionals

    NASA Technical Reports Server (NTRS)

    Dey, S. K.

    1985-01-01

    A perturbed functional iteration has been developed to solve nonlinear systems. It adds at each iteration level, unique perturbation parameters to nonlinear Gauss-Seidel iterates which enhances its convergence properties. As convergence is approached these parameters are damped out. Local linearization along the diagonal has been used to compute these parameters. The method requires no computation of Jacobian or factorization of matrices. Analysis of convergence depends on properties of certain contraction-type mappings, known as D-mappings. In this article, application of this method to solve an implicit finite difference approximation of Euler's equation is studied. Some representative results for the well known shock tube problem and compressible flows in a nozzle are given.

  18. Workforce Investments: State Strategies to Preserve Higher-Cost Career Education Programs in Community and Technical Colleges

    ERIC Educational Resources Information Center

    Shulock, Nancy; Lewis, Jodi; Tan, Connie

    2013-01-01

    In today's highly-skilled economy, rewarding career pathways are available to those who acquire technical skills by enrolling in certificate and associate degree programs in a community or technical college. Such programs are often more costly to offer than liberal arts and sciences programs that prepare students to transfer to four-year…

  19. 24 CFR 891.175 - Technical assistance.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Technical assistance. 891.175... Requirements § 891.175 Technical assistance. For purposes of the Section 202 Program and the Section 811 Program, the Secretary shall make available appropriate technical assistance to assure that applicants...

  20. 10 CFR 905.40 - Technical assistance.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Technical assistance. 905.40 Section 905.40 Energy DEPARTMENT OF ENERGY ENERGY PLANNING AND MANAGEMENT PROGRAM Energy Services § 905.40 Technical assistance. Western shall establish a program that provides technical assistance to customers to conduct integrated...

  1. 75 FR 34251 - Office of Special Education and Rehabilitative Services; Overview Information; Centers for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-16

    ... Information; Centers for Independent Living Program--Training and Technical Assistance; Notice Inviting... Training and Technical Assistance Project. Program Authority: 29 U.S.C. 796f(b); American Recovery and... Independent Living Program--Training and Technical Assistance--CFDA Number 84.400B must be submitted...

  2. 77 FR 16250 - Notice of Proposed Information Collection for Public Comment; Office of Native American Programs...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-20

    ... Information Collection for Public Comment; Office of Native American Programs (ONAP) Training and Technical... subject proposal. The data required by Office of Native American Programs Training and Technical... progress. The data identifies needs, outputs and outcomes of the training and technical assistance. DATES...

  3. 77 FR 9216 - Native American Career and Technical Education Program; Proposed Waivers and Extension of the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-16

    ... DEPARTMENT OF EDUCATION Native American Career and Technical Education Program; Proposed Waivers... Education, Department of Education. ACTION: Notice. SUMMARY: For 60-month projects funded in fiscal year (FY) 2007 under the Native American Career and Technical Education Program (NACTEP), the Secretary proposes...

  4. NASA Technical Standards Program and Implications for Lessons Learned and Technical Standard Integration

    NASA Technical Reports Server (NTRS)

    Gill, Paul S.; Garcia, Danny; Vaughan, William W.; Parker, Nelson C. (Technical Monitor)

    2002-01-01

    The National Aeronautics and Space Agency consists of fourteen Facilities throughout the United States. They are organized to support the Agency's principal Enterprises: (1) Space Science, (2) Earth Science, (3) Aerospace Technology, (4) Human Exploration and Development of Space, and (5) Biological and Physical Research. Technical Standards are important to the activities of each Enterprise and have been an integral part in the development and operation of NASA Programs and Projects since the Agency was established in 1959. However, for years each Center was responsible for its own standards development and selection of non-NASA technical standards that met the needs of Programs and Projects for which they were responsible. There were few Agencywide applicable Technical Standards, mainly those in area of safety. Department of Defense Standards and Specifications were the foundation and main source for Technical Standards used by the Agency. This process existed until about 1997 when NASA embarked on a Program to convert NASA's Center-developed Technical Standards into Agencywide endorsed NASA Preferred Technical Standards. In addition, action was taken regarding the formal adoption of non-NASA Technical Standards (DOD, SAE, ASTM, ASME, IEEE, etc.) as NASA Preferred Technical Standards.

  5. 40 CFR 52.2586 - Small business stationary source technical and environmental compliance assistance program.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... PLANS (CONTINUED) Wisconsin § 52.2586 Small business stationary source technical and environmental compliance assistance program. The Wisconsin small business stationary source technical and environmental...

  6. 40 CFR 52.2586 - Small business stationary source technical and environmental compliance assistance program.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... PLANS (CONTINUED) Wisconsin § 52.2586 Small business stationary source technical and environmental compliance assistance program. The Wisconsin small business stationary source technical and environmental...

  7. 40 CFR 52.2586 - Small business stationary source technical and environmental compliance assistance program.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... PLANS (CONTINUED) Wisconsin § 52.2586 Small business stationary source technical and environmental compliance assistance program. The Wisconsin small business stationary source technical and environmental...

  8. 40 CFR 52.2586 - Small business stationary source technical and environmental compliance assistance program.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... PLANS (CONTINUED) Wisconsin § 52.2586 Small business stationary source technical and environmental compliance assistance program. The Wisconsin small business stationary source technical and environmental...

  9. 40 CFR 52.2586 - Small business stationary source technical and environmental compliance assistance program.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... PLANS (CONTINUED) Wisconsin § 52.2586 Small business stationary source technical and environmental compliance assistance program. The Wisconsin small business stationary source technical and environmental...

  10. 77 FR 20369 - Applications for New Awards; Centers for Independent Living-Training and Technical Assistance

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-04

    ... Education ACTION: Notice. Overview Information Centers for Independent Living--Training and Technical.... Funding Opportunity Description Purpose of Program The purpose of the Training and Technical Assistance grant under the Centers for Independent Living program is to provide training and technical assistance...

  11. Waukesha County Technical College 1998 Comprehensive Annual Financial Report.

    ERIC Educational Resources Information Center

    Tessmann, Cary A.

    Waukesha County Technical College (WCTC) is one of 16 institutions in the Wisconsin Technical College System. The college offers associate of applied science degree programs, technical diplomas and certificates, apprenticeship programs and other adult education services. This financial report covers fiscal year 1998 and is divided into four…

  12. Project T.E.A.M. (Technical Education Advancement Modules). Final Report.

    ERIC Educational Resources Information Center

    Greenville Technical Coll., SC.

    Project TEAM (Technical Education Advancement Modules), a cooperative demonstration program for high technology training, created an introductory technical training program and a consumer education package emphasizing the benefits of technical training. The curriculum and training focus of the project began with an assessment of employee needs in…

  13. Technical Assistance and Program Support; DOD Historical Black Colleges and Universities and Minority Institutions Program.

    DTIC Science & Technology

    2000-04-01

    AD Award Number: DAMD17-98-2-8012 TITLE: Technical Assistance and Program Support; DOD Historical Black Colleges and Universities and Minority...2000 3. REPORT TYPE AND DATES COVERED Annual (1 May 99 - 30 Apr 00): 4. TITLE AND SUBTITLE Technical Assistance and Program Support; DOD...UNCF’s Infrastructure Development Assistance Program (IDAP) has been involved myriad of tasks to support the Department of Defense’s interest to

  14. New Wine in New Bottles: Transforming Vocational Education into Career and Technical Education. Practice Application Brief No. 21.

    ERIC Educational Resources Information Center

    Brown, Bettina Lankard

    Teachers responsible for transforming their vocational education programs into career and technical education (CTE) programs need to concentrate on ensuring programs' technical and academic rigor, engaging in collaboration in school and in the community, keeping current through professional development experiences, and extending learning beyond…

  15. 77 FR 15995 - Notice of Request for Extension of a Currently Approved Information Collection

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-19

    ... information collection in support of the program for Self-Help Technical Assistance Grants (7 CFR part 1944-I...-0783, Telephone (202) 720-1489. SUPPLEMENTARY INFORMATION: Title: 7 CFR 1944-I, Self-Help Technical... programs of technical and supervisory assistance for self-help housing loan program, as authorized under...

  16. Structure in Community College Career-Technical Programs: A Qualitative Analysis. CCRC Working Paper No. 50

    ERIC Educational Resources Information Center

    Van Noy, Michelle; Weiss, Madeline Joy; Jenkins, Davis; Barnett, Elisabeth A.; Wachen, John

    2012-01-01

    Using data obtained from interviews and program websites at Washington community and technical colleges, the authors of this study examine the structure of community college career-technical programs in allied health, business and marketing, computer and information studies, and mechanics and repair. A framework for structure with four…

  17. 48 CFR 252.227-7018 - Rights in noncommercial technical data and computer software-Small Business Innovation Research...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... technical data and computer software-Small Business Innovation Research (SBIR) Program. 252.227-7018 Section... Innovation Research (SBIR) Program. As prescribed in 227.7104(a), use the following clause: Rights in Noncommercial Technical Data and Computer Software—Small Business Innovation Research (SBIR) Program (JUN 1995...

  18. 48 CFR 252.227-7018 - Rights in noncommercial technical data and computer software-Small Business Innovation Research...

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... technical data and computer software-Small Business Innovation Research (SBIR) Program. 252.227-7018 Section... Innovation Research (SBIR) Program. As prescribed in 227.7104(a), use the following clause: Rights in Noncommercial Technical Data and Computer Software—Small Business Innovation Research (SBIR) Program (FEB 2014...

  19. 48 CFR 252.227-7018 - Rights in noncommercial technical data and computer software-Small Business Innovation Research...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... technical data and computer software-Small Business Innovation Research (SBIR) Program. 252.227-7018 Section... Innovation Research (SBIR) Program. As prescribed in 227.7104(a), use the following clause: Rights in Noncommercial Technical Data and Computer Software—Small Business Innovation Research (SBIR) Program (MAR 2011...

  20. 48 CFR 252.227-7018 - Rights in noncommercial technical data and computer software-Small Business Innovation Research...

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... technical data and computer software-Small Business Innovation Research (SBIR) Program. 252.227-7018 Section... Innovation Research (SBIR) Program. As prescribed in 227.7104(a), use the following clause: Rights in Noncommercial Technical Data and Computer Software—Small Business Innovation Research (SBIR) Program (MAY 2013...

  1. Computer Programs for Technical Communicators: The Compelling Curriculum. Working Draft.

    ERIC Educational Resources Information Center

    Selfe, Cynthia L.; Wahlstrom, Billie J.

    A series of computer programs have been developed at Michigan Technological University for use with technical writing and technical communications classes. The first type of program in the series, CURIE II, includes process-based modules, each of which corresponds to one of the following assignments: memoranda, resumes, feasibility reports,…

  2. 77 FR 30512 - Native American Career and Technical Education Program; Final Waivers and Extension of Project...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-23

    ... DEPARTMENT OF EDUCATION Native American Career and Technical Education Program; Final Waivers and... American Career and Technical Education Program Catalog of Federal Domestic Assistance (CFDA) Number: 84.101A. SUMMARY: For 60-month projects funded in fiscal year (FY) 2007 under the Native American Career...

  3. Toward an objective assessment of technical skills: a national survey of surgical program directors in Saudi Arabia.

    PubMed

    Alkhayal, Abdullah; Aldhukair, Shahla; Alselaim, Nahar; Aldekhayel, Salah; Alhabdan, Sultan; Altaweel, Waleed; Magzoub, Mohi Elden; Zamakhshary, Mohammed

    2012-01-01

    After almost a decade of implementing competency-based programs in postgraduate training programs, the assessment of technical skills remains more subjective than objective. National data on the assessment of technical skills during surgical training are lacking. We conducted this study to document the assessment tools for technical skills currently used in different surgical specialties, their relationship with remediation, the recommended tools from the program directors' perspective, and program directors' attitudes toward the available objective tools to assess technical skills. This study was a cross-sectional survey of surgical program directors (PDs). The survey was initially developed using a focus group and was then sent to 116 PDs. The survey contains demographic information about the program, the objective assessment tools used, and the reason for not using assessment tools. The last section discusses the recommended tools to be used from the PDs' perspective and the PDs' attitude and motivation to apply these tools in each program. The associations between the responses to the assessment questions and remediation were statistically evaluated. Seventy-one (61%) participants responded. Of the respondents, 59% mentioned using only nonstandardized, subjective, direct observation for technical skills assessment. Sixty percent use only summative evaluation, whereas 15% perform only formative evaluations of their residents, and the remaining 22% conduct both summative and formative evaluations of their residents' technical skills. Operative portfolios are kept by 53% of programs. The percentage of programs with mechanisms for remediation is 29% (19 of 65). The survey showed that surgical training programs use different tools to assess surgical skills competency. Having a clear remediation mechanism was highly associated with reporting remediation, which reflects the capability to detect struggling residents. Surgical training leadership should invest more in standardizing the assessment of surgical skills.

  4. [Endovascular radiofrequency denervation of renal arteries as an innovation method of treatment of refractory arterial hypertension. First experience in Russia].

    PubMed

    Danilov, N M; Matchin, Iu G; Chazova, I E

    2012-01-01

    Excessive activation of the sympathetic nervous system forms the basis of pathogenesis of essential arterial hypertension (AH). The present work was aimed at evaluating efficacy and safety of endovascular radiofrequency denervation of renal arteries in patients with AH refractory AH based on the initial first experience in with using this methodology in the Russian Federation. The interventions were carried out on December 14-15th, 2011 in the first five patients presenting with AH refractory to antihypertensive therapy consisting of three and more drugs in therapeutic doses, one of which was a diuretic. The selection criteria were systolic arterial pressure (SAP) ≥160 mm Hg or ≥150 mm Hg in the presence of type 2 diabetes mellitus. The obligatory conditions for selection were the preserved renal function [glomerular filtration rate (GFR) ≥45 ml/min] and the absence of the secondary form of AH. The procedure of denervation was performed in the conditions of roentgen-operating room using special Medtronic Ardian Simplicity Catheter System™. In all cases we managed to perform bilateral denervation of renal arteries with the radiofrequency effect in not less than 4 zones of each of vessels. Efficacy of each of the effect was registered with due regard for reaching certain temperature and values of impedance. The interventions were not accompanied by the development of any complications either in the area of manipulations or the site of puncture. Neither were there any complications from the side of the cardiovascular or excretory systems of the body. Diurnal monitoring of AP (DMAP) registered a significant decrease in SAP averagely from 174±12 to 145±10 mm Hg three days after the intervention. A persistent antihypertensive effect was confirmed by the DMAP findings one month after denervation - the SAP level averagely amounted to 131±6 mm Hg. Endovascular radiofrequency denervation of renal arteries is a safe and efficient method of treatment of AH resistant to multicomponent antihypertensive therapy.

  5. Azapsoralens: new potential photochemotherapeutic agents for psoriasis.

    PubMed

    Vedaldi, D; Caffieri, S; Miolo, G; Dall'Acqua, F; Baccichetti, F; Guiotto, A; Benetollo, F; Bombieri, G; Recchia, G; Cristofolini, M

    1991-12-01

    New bioisoters of psoralen, obtained by replacing carbon 8 of the central benzene ring with a nitrogen, were studied from the photochemical, photobiological and phototherapeutic points of view. In particular, 4,4'-, 4',5'-dimetyl, 4,4',5'-trimethyl and 3,4,4',5'-tetramethylazapsoralen were studied. The crystal and molecular structure of 4,4',5'-trimethylazapsoralen, obtained by X ray diffraction, was also reported. Like psoralen, these compounds form a molecular complex with DNA, undergoing intercalation inside the double helix of the macromolecule. When irridiated with long ultraviolet light (365 nm), the intercalated drug photoconjugates covalently to the macromolecule, forming mono- and diadducts. The photobinding rate show the following order of magnitude: 4,4',5'-trimetylazapsoralen (4,4',5'-TMAP) = 3,4,4',5'-tetramethylazapsoralen (3,4,4',5'-TMAP) greater than 4',5'-dimethylazapsoralen (4',5'-DMAP) = 4,4'-dimethylazapsoralen (4,4'-DMAP). The DNA photobinding rate of 8-methoxypsoralen (8-MOP), taken as reference compound, is similar to that of the two dimetylazapsoralens but lower than tri- and tetramethyl derivatives. The ability of azapsoralens to form cross-links in DNA is lower than that of 8-MOP. However, capacity to induce cross-links does not parallel the DNA photobinding rate; it is higher for trimethyl derivate and lower for tetramethylazapsoralen. Azapsoralens show evident antiproliferative activity. The trimethyl derivative is the most active, followed by tetrametyl, both these compounds showing activity slightly higher than that of 8-MOP. The two dimethylderivatives are less active. The mautagenic activity of azapsoralens on E. coli WP2 TM6 is lower than that of 8-MOP in the same conditions. The new compounds do not show any skin phototoxicity on guinea pig skin. On the basis of its DNA photobinding, antiproliferative activity, mutagenicity and lack of skin phototoxicity, 4,4',5'-TMAP was chosen for clinical evaluation. Clinical results obtained by topical treatment of psoriatic plaques reveal evident therapeutic effectiveness and clearing is between good and moderate, although 8-MOP, used as reference compound, is more effective.

  6. MDGA2 is a novel tumour suppressor cooperating with DMAP1 in gastric cancer and is associated with disease outcome.

    PubMed

    Wang, Kunning; Liang, Qiaoyi; Li, Xiaoxing; Tsoi, Ho; Zhang, Jingwan; Wang, Hua; Go, Minnie Y Y; Chiu, Philip W Y; Ng, Enders K W; Sung, Joseph J Y; Yu, Jun

    2016-10-01

    Using the promoter methylation assay, we have shown that MDGA2 (MAM domain containing glycosylphosphatidylinositol anchor 2) is preferentially methylated in gastric cancer. We analysed its biological effects and prognostic significance in gastric cancer. MDGA2 methylation status was evaluated by combined bisulfite restriction analysis and bisulfite genomic sequencing. The effects of MDGA2 re-expression or knockdown on cell proliferation, apoptosis and the cell cycle were determined. MDGA2 interacting protein was identified by mass spectrometry and MDGA2-related cancer pathways by reporter activity and PCR array analyses. The clinical impact of MDGA2 was assessed in 218 patients with gastric cancer. MDGA2 was commonly silenced in gastric cancer cells (10/11) and primary gastric cancers due to promoter hypermethylation. MDGA2 significantly inhibited cell proliferation by causing G1-S cell cycle arrest and inducing cell apoptosis in vitro, and suppressed xenograft tumour growth in both subcutaneous and orthotopic xenograft mouse models (both p<0.001). The anti-tumorigenic effect of MDGA2 was mediated through direct stabilising of DNA methyltransferase 1 associated protein 1 (DMAP1), which played a tumour suppressive role in gastric cancer. This interaction activated their downstream key elements of p53/p21 signalling cascades. Moreover, promoter methylation of MDGA2 was detected in 62.4% (136/218) of gastric cancers. Multivariate analysis showed that patients with MDGA2 hypermethylation had a significantly decreased survival (p=0.005). Kaplan-Meier survival curves showed that MDGA2 hypermethylation was significantly associated with shortened survival in patients with early gastric cancer. MDGA2 is a critical tumour suppressor in gastric carcinogenesis; its hypermethylation is an independent prognostic factor in patients with gastric cancer. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  7. IAC-1.5 - INTEGRATED ANALYSIS CAPABILITY

    NASA Technical Reports Server (NTRS)

    Vos, R. G.

    1994-01-01

    The objective of the Integrated Analysis Capability (IAC) system is to provide a highly effective, interactive analysis tool for the integrated design of large structures. IAC was developed to interface programs from the fields of structures, thermodynamics, controls, and system dynamics with an executive system and a database to yield a highly efficient multi-disciplinary system. Special attention is given to user requirements such as data handling and on-line assistance with operational features, and the ability to add new modules of the user's choice at a future date. IAC contains an executive system, a database, general utilities, interfaces to various engineering programs, and a framework for building interfaces to other programs. IAC has shown itself to be effective in automating data transfer among analysis programs. The IAC system architecture is modular in design. 1) The executive module contains an input command processor, an extensive data management system, and driver code to execute the application modules. 2) Technical modules provide standalone computational capability as well as support for various solution paths or coupled analyses. 3) Graphics and model generation modules are supplied for building and viewing models. 4) Interface modules provide for the required data flow between IAC and other modules. 5) User modules can be arbitrary executable programs or JCL procedures with no pre-defined relationship to IAC. 6) Special purpose modules are included, such as MIMIC (Model Integration via Mesh Interpolation Coefficients), which transforms field values from one model to another; LINK, which simplifies incorporation of user specific modules into IAC modules; and DATAPAC, the National Bureau of Standards statistical analysis package. The IAC database contains structured files which provide a common basis for communication between modules and the executive system, and can contain unstructured files such as NASTRAN checkpoint files, DISCOS plot files, object code, etc. The user can define groups of data and relations between them. A full data manipulation and query system operates with the database. The current interface modules comprise five groups: 1) Structural analysis - IAC contains a NASTRAN interface for standalone analysis or certain structural/control/thermal combinations. IAC provides enhanced structural capabilities for normal modes and static deformation analysis via special DMAP sequences. 2) Thermal analysis - IAC supports finite element and finite difference techniques for steady state or transient analysis. There are interfaces for the NASTRAN thermal analyzer, SINDA/SINFLO, and TRASYS II. 3) System dynamics - A DISCOS interface allows full use of this simulation program for either nonlinear time domain analysis or linear frequency domain analysis. 4) Control analysis - Interfaces for the ORACLS, SAMSAN, NBOD2, and INCA programs allow a wide range of control system analyses and synthesis techniques. 5) Graphics - The graphics packages PLOT and MOSAIC are included in IAC. PLOT generates vector displays of tabular data in the form of curves, charts, correlation tables, etc., while MOSAIC generates color raster displays of either tabular of array type data. Either DI3000 or PLOT-10 graphics software is required for full graphics capability. IAC is available by license for a period of 10 years to approved licensees. The licensed program product includes one complete set of supporting documentation. Additional copies of the documentation may be purchased separately. IAC is written in FORTRAN 77 and has been implemented on a DEC VAX series computer operating under VMS. IAC can be executed by multiple concurrent users in batch or interactive mode. The basic central memory requirement is approximately 750KB. IAC includes the executive system, graphics modules, a database, general utilities, and the interfaces to all analysis and controls programs described above. Source code is provided for the control programs ORACLS, SAMSAN, NBOD2, and DISCOS. The following programs are also available from COSMIC a

  8. IAC-1.5 - INTEGRATED ANALYSIS CAPABILITY

    NASA Technical Reports Server (NTRS)

    Vos, R. G.

    1994-01-01

    The objective of the Integrated Analysis Capability (IAC) system is to provide a highly effective, interactive analysis tool for the integrated design of large structures. IAC was developed to interface programs from the fields of structures, thermodynamics, controls, and system dynamics with an executive system and a database to yield a highly efficient multi-disciplinary system. Special attention is given to user requirements such as data handling and on-line assistance with operational features, and the ability to add new modules of the user's choice at a future date. IAC contains an executive system, a database, general utilities, interfaces to various engineering programs, and a framework for building interfaces to other programs. IAC has shown itself to be effective in automating data transfer among analysis programs. The IAC system architecture is modular in design. 1) The executive module contains an input command processor, an extensive data management system, and driver code to execute the application modules. 2) Technical modules provide standalone computational capability as well as support for various solution paths or coupled analyses. 3) Graphics and model generation modules are supplied for building and viewing models. 4) Interface modules provide for the required data flow between IAC and other modules. 5) User modules can be arbitrary executable programs or JCL procedures with no pre-defined relationship to IAC. 6) Special purpose modules are included, such as MIMIC (Model Integration via Mesh Interpolation Coefficients), which transforms field values from one model to another; LINK, which simplifies incorporation of user specific modules into IAC modules; and DATAPAC, the National Bureau of Standards statistical analysis package. The IAC database contains structured files which provide a common basis for communication between modules and the executive system, and can contain unstructured files such as NASTRAN checkpoint files, DISCOS plot files, object code, etc. The user can define groups of data and relations between them. A full data manipulation and query system operates with the database. The current interface modules comprise five groups: 1) Structural analysis - IAC contains a NASTRAN interface for standalone analysis or certain structural/control/thermal combinations. IAC provides enhanced structural capabilities for normal modes and static deformation analysis via special DMAP sequences. 2) Thermal analysis - IAC supports finite element and finite difference techniques for steady state or transient analysis. There are interfaces for the NASTRAN thermal analyzer, SINDA/SINFLO, and TRASYS II. 3) System dynamics - A DISCOS interface allows full use of this simulation program for either nonlinear time domain analysis or linear frequency domain analysis. 4) Control analysis - Interfaces for the ORACLS, SAMSAN, NBOD2, and INCA programs allow a wide range of control system analyses and synthesis techniques. 5) Graphics - The graphics packages PLOT and MOSAIC are included in IAC. PLOT generates vector displays of tabular data in the form of curves, charts, correlation tables, etc., while MOSAIC generates color raster displays of either tabular of array type data. Either DI3000 or PLOT-10 graphics software is required for full graphics capability. IAC is available by license for a period of 10 years to approved licensees. The licensed program product includes one complete set of supporting documentation. Additional copies of the documentation may be purchased separately. IAC is written in FORTRAN 77 and has been implemented on a DEC VAX series computer operating under VMS. IAC can be executed by multiple concurrent users in batch or interactive mode. The basic central memory requirement is approximately 750KB. IAC includes the executive system, graphics modules, a database, general utilities, and the interfaces to all analysis and controls programs described above. Source code is provided for the control programs ORACLS, SAMSAN, NBOD2, and DISCOS. The following programs are also available from COSMIC as separate packages: NASTRAN, SINDA/SINFLO, TRASYS II, DISCOS, ORACLS, SAMSAN, NBOD2, and INCA. IAC was developed in 1985.

  9. Investigating Employability: A Study to Ascertain Whether Attaining Stackable Credentials Increases Opportunity for Employment for Career Technical Graduates

    ERIC Educational Resources Information Center

    Whittington, Amy Green

    2017-01-01

    Career technical education plays an important part in the mission of community colleges--providing educational opportunities needed by members of their communities. Career technical programs prepare students for entry into the workforce. Accountability standards for career technical programs, from local, state, and federal bodies, monitor…

  10. 48 CFR 252.227-7018 - Rights in noncommercial technical data and computer software-Small Business Innovation Research...

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... technical data and computer software-Small Business Innovation Research (SBIR) Program. 252.227-7018 Section... Clauses 252.227-7018 Rights in noncommercial technical data and computer software—Small Business... Noncommercial Technical Data and Computer Software—Small Business Innovation Research (SBIR) Program (MAR 2011...

  11. Announcement Notice (AN) 241.4 - Software | OSTI, US Dept of Energy Office

    Science.gov Websites

    of Scientific and Technical Information Skip to main content Scientific and Technical Information Program The home of the U.S. Department of Energy's Scientific and Technical Information Program ) Scientific and Technical Information (STI) products for announcement and availability. An AN includes review

  12. IMPLICATIONS OF WOMEN'S WORK PATTERNS FOR PROGRAM DEVELOPMENT IN VOCATIONAL AND TECHNICAL EDUCATION.

    ERIC Educational Resources Information Center

    LEE, SYLVIA L.; AND OTHERS

    THE IMPLICATIONS OF WOMEN'S LABOR FORCE PARTICIPATION FOR EDUCATORS AND LEADERS PLANNING PROGRAMS IN VOCATIONAL AND TECHNICAL EDUCATION WERE DERIVED AT A 2-DAY CONFERENCE BY 30 PEOPLE REPRESENTING THE VARIOUS SERVICES IN VOCATIONAL-TECHNICAL EDUCATION AND RELATED AREAS. IMPLICATIONS AND RECOMMENDATIONS FOR VOCATIONAL AND TECHNICAL EDUCATION…

  13. An Interdisciplinary Program in Technical Communications: Problems Encountered.

    ERIC Educational Resources Information Center

    Eckman, Martha

    The need for experts in technical communication is growing significantly while the number of college graduates in the field accounts for less than one percent of the need. Three major types of problems should be considered in trying to establish a technical communication program: those involving society's need for better technical communicators,…

  14. A Case Study of Technical Assistance to Demonstration Programs for Young Handicapped Children. Part II.

    ERIC Educational Resources Information Center

    Behr, Shirley K.; And Others

    A project to provide technical assistance to staffs of two demonstration programs for preschool handicapped children and their families is described. The focus was technical assistance developed and exercised by the Technical Assistance Development System (TADS), which assisted in the development of the Handicapped Children's Early Education…

  15. A Case Study of Technical Assistance to Demonstration Programs for Young Handicapped Children. Part I.

    ERIC Educational Resources Information Center

    Behr, Shirley K.; And Others

    The interim report presents an evaluation of TADS (Technical Assistance Development System) through case studies of TADS technical assistance to the staffs of two demonstration programs for preschool handicapped children and their families. Purposes of the study included obtaining indepth descriptions of the technical assistance process to…

  16. 14 CFR 399.91 - Air carrier participation in programs of technical assistance to airlines of less developed...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... § 399.91 Air carrier participation in programs of technical assistance to airlines of less developed... 14 Aeronautics and Space 4 2011-01-01 2011-01-01 false Air carrier participation in programs of technical assistance to airlines of less developed countries. 399.91 Section 399.91 Aeronautics and Space...

  17. 14 CFR 399.91 - Air carrier participation in programs of technical assistance to airlines of less developed...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... § 399.91 Air carrier participation in programs of technical assistance to airlines of less developed... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Air carrier participation in programs of technical assistance to airlines of less developed countries. 399.91 Section 399.91 Aeronautics and Space...

  18. A Comparison of the Career and Technical Education Programs in a US Community College and a Chinese Institution

    ERIC Educational Resources Information Center

    Hou, Harry

    2010-01-01

    This research study explores and compares the career and technical education programs offered in a US community college and the vocational/career and technology education programs offered in a comparable Chinese postsecondary institution. The study sought to find positive transferable characteristics of the career and technical education programs…

  19. Interaction of the HIV NCp7 Protein with Platinum(II) and Gold(III) Complexes Containing Tridentate Ligands.

    PubMed

    Bernardes, Victor H F; Qu, Yun; Du, Zhifeng; Beaton, James; Vargas, Maria D; Farrell, Nicholas P

    2016-11-07

    The human immunodeficiency virus (HIV) nucleocapsid protein (NCp7) plays significant roles in the virus life cycle and has been targeted by compounds that could lead to its denaturation or block its interaction with viral RNA. Herein, we describe the interactions of platinum(II) and gold(III) complexes with NCp7 and how the reactivity/affinity of potential inhibitors can be modulated by judicious choice of ligands. The interactions of [MCl(N 3 )] n+ (M = Pt 2+ (n = 1) and Au 3+ (n = 2); N 3 = tridentate chelate ligands: bis(2-pyridylmethyl)methylamine (Mebpma, L 1 ) and bis(2-pyridylmethyl)amine (bpma, L 2 ) with the C-terminal zinc finger of NCp7 (ZF2) were investigated by electrospray ionization-mass spectroscopy (ESI-MS). Mass spectra from the incubation of [MCl(Mebpma)] n+ complexes (PtL 1 and AuL 1 ) with ZF2 indicated that they were more reactive than the previously studied diethylenetriamine-containing analogues [MCl(dien)] n+ . The initial product of reaction of PtL 1 with ZF2 results in loss of all ligands and release of zinc to give the platinated apopeptide {PtF} (F = apopeptide). This is in contrast to the incubation with [PtCl(dien)] + , in which {Pt(dien)}-peptide adducts are observed. Incubation of the Au 3+ complex AuL 1 with ZF2 gave Au x F n+ species (x = 1, 2, 4, F = apopeptide) again with loss of all ligands. Furthermore, the formally substitution-inert analogues [Pt(N 3 )L] 2+ (L = 4-methylpyridine (4-pic), 4-dimethylaminopyridine (dmap), and 9-ethylguanine (9-EtGua)) were prepared to examine stacking interactions with N-acetyltryptophan (N-AcTrp), the Trp-containing ZF2, and the "full" two-finger NCp7 itself using fluorescence quenching titration. Use of bpma and Mebpma gave slightly higher affinity than analogous [Pt(dien)L)] 2+ complexes. The dmap-containing complexes (PtL 1 a and PtL 2 a) had the greatest association constants (K a ) for N-AcTrp and ZF2 peptide. The complex PtL 1 a had the highest K a when compared with other known Pt 2+ analogues: [Pt(dien)(9-EtGua)] 2+ < [Pt(bpma)(9-EtGua)] 2+ < [Pt(dien)(dmap)] 2+ < PtL 2 a < PtL 1 a. A K a value of ca. 40.6 ± 1.0 × 10 3 M -1 was obtained for the full NCp7 peptide with PtL 1 a. In addition, the mass spectrum of the interaction between ZF2 and PtL 1 a confirms formation of a 1:1 PtL 1 a/ZF2 adduct. The reactivity of selected complexes with sulfur-containing amino acid N-acetylcysteine (N-AcCys) was also investigated by 195 Pt and 1 H NMR spectroscopy and ESI-MS. The precursor compounds [PtCl(N 3 )] + PtL 1 and PtL 2 reacted readily, whereas their [Pt(N 3 )L] 2+ analogues PtL 1 a and PtL 2 a were inert to substitution.

  20. Communication Requirements of Employees of Business and Industry Represented by Areas of Technological Study at Southern Maine Vocational Technical Institute.

    ERIC Educational Resources Information Center

    Cary, Penny J.; Sweeney, Kevin F.

    A study examined the need and demand for communication skills for employees in the technical fields for which Southern Maine Vocational Technical Institute offers programs of academic preparation. Two members of the Institute's English Department interviewed representatives of organizations that have hired technical program graduates. Further…

  1. Copyrighted Software | OSTI, US Dept of Energy Office of Scientific and

    Science.gov Websites

    Technical Information Skip to main content Scientific and Technical Information Program The home of the U.S. Department of Energy's Scientific and Technical Information Program (STIP) Here you Energy U.S. Department of Energy Office of Science Office of Scientific and Technical information Website

  2. About STIP | OSTI, US Dept of Energy Office of Scientific and Technical

    Science.gov Websites

    Information Skip to main content Scientific and Technical Information Program The home of the U.S. Department of Energy's Scientific and Technical Information Program (STIP) Here you will find through scientific and technical information (STI), a key outcome of DOE R&D and other activities

  3. Contact Us | OSTI, US Dept of Energy Office of Scientific and Technical

    Science.gov Websites

    Information Skip to main content Scientific and Technical Information Program The home of the U.S. Department of Energy's Scientific and Technical Information Program (STIP) Here you will find MAIL TO: U.S. Department of Energy Office of Scientific and Technical Information ATTN: STIP P.O. Box

  4. Linked Learning: Can Career and Technical Education Programs Take California High Schools into the 21st Century?

    ERIC Educational Resources Information Center

    Adams, Brian Edward

    2012-01-01

    This qualitative study explored the ability of a linked learning career and technical education program to engage fully students and thereby increase at-risk students' persistence in school. The focus was to identify the degree to which linked learning career and technical education programs provide a community atmosphere, increase and maintained…

  5. Seizing the Future: How Ohio's Career-Technical Education Programs Fuse Academic Rigor and Real-World Experiences to Prepare Students for College and Careers

    ERIC Educational Resources Information Center

    Guarino, Heidi; Yoder, Shaun

    2015-01-01

    "Seizing the Future: How Ohio's Career and Technical Education Programs Fuse Academic Rigor and Real-World Experiences to Prepare Students for College and Work," demonstrates Ohio's progress in developing strong policies for career and technical education (CTE) programs to promote rigor, including college- and career-ready graduation…

  6. A Survey of Vocational Administrators and Teachers in Career and Technical Education Centers regarding Their Perception of Vocational Program Improvements

    ERIC Educational Resources Information Center

    Hummel, Richard Lynn, Jr.

    2012-01-01

    The purpose of this statewide study is to assess the perceived improvements made to programs that are offered at Career and Technical Education Centers from the perspective of vocational administrators and teachers following the Bureau of Career and Technical Education conduction of an Approved Program Evaluation. The Pennsylvania Bureau of Career…

  7. A Case Study of Technical Assistance to Demonstration Programs for Young Handicapped Children. Part III.

    ERIC Educational Resources Information Center

    Behr, Shirley K.; And Others

    The report describes the third and final year of a 3-year case study of the technical assistance process as implemented by the Technical Assistance Development System (TADS) for the staffs of two demonstration programs for preschool handicapped children and their families. Following a review of TADS and the two demonstration programs, the…

  8. Professional Development Programs in Community and Technical Colleges: Are Occupational-Technical Faculty Well Served?

    ERIC Educational Resources Information Center

    Hoerner, James L.; And Others

    1991-01-01

    According to a survey receiving 878 responses from 1,252 community/technical colleges, (1) 708 have professional development programs; (2) 48% rarely offer programs to part-time faculty; (3) funding was healthy for full-time, but 74% had no funding for part-time faculty development; and (4) incentives included intrinsic reward (80%), travel funds…

  9. 48 CFR 719.271-5 - Cognizant technical officers.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... DEVELOPMENT SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Policies 719.271-5 Cognizant technical officers. Since the procurement process starts with the establishment of a requirement, the actions of the cognizant technical officers can affect the opportunity of small business to participate equitably...

  10. 48 CFR 719.271-5 - Cognizant technical officers.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... officers. 719.271-5 Section 719.271-5 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Policies 719.271-5 Cognizant technical officers... cognizant technical officers can affect the opportunity of small business to participate equitably...

  11. 4-(Di­methyl­amino)­pyridinium trichlorido[4-(di­methyl­amino)­pyridine-κN]cobaltate(II)

    PubMed Central

    Guenifa, Fatiha; Hadjadj, Nasreddine; Zeghouan, Ouahida; Bendjeddou, Lamia; Merazig, Hocine

    2013-01-01

    In the anion of the title compound, (C7H11N2)[CoCl3(C7H10N2)], the CoII ion is coordinated by one N atom from a 4-(di­methyl­amino)­pyridine (DMAP) ligand and three Cl atoms, forming a CoNCl3 polyhedron with a distorted tetra­hedral geometry. In the crystal, cations and anions are linked via weak N—H⋯Cl and C—H⋯Cl hydrogen bonds. Double layers of complex anions stack along the b- axis direction, which alternate with double layers of 4-(di­methyl­amino)-pyridinium cations. PMID:24046560

  12. A TEMPO-free copper-catalyzed aerobic oxidation of alcohols.

    PubMed

    Xu, Boran; Lumb, Jean-Philip; Arndtsen, Bruce A

    2015-03-27

    The copper-catalyzed aerobic oxidation of primary and secondary alcohols without an external N-oxide co-oxidant is described. The catalyst system is composed of a Cu/diamine complex inspired by the enzyme tyrosinase, along with dimethylaminopyridine (DMAP) or N-methylimidazole (NMI). The Cu catalyst system works without 2,2,6,6-tetramethyl-l-piperidinoxyl (TEMPO) at ambient pressure and temperature, and displays activity for un-activated secondary alcohols, which remain a challenging substrate for catalytic aerobic systems. Our work underscores the importance of finding alternative mechanistic pathways for alcohol oxidation, which complement Cu/TEMPO systems, and demonstrate, in this case, a preference for the oxidation of activated secondary over primary alcohols. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  13. A reagent for safe and efficient diazo-transfer to primary amines: 2-azido-1,3-dimethylimidazolinium hexafluorophosphate.

    PubMed

    Kitamura, Mitsuru; Kato, So; Yano, Masakazu; Tashiro, Norifumi; Shiratake, Yuichiro; Sando, Mitsuyoshi; Okauchi, Tatsuo

    2014-07-07

    Organic azides were prepared from primary amines in high yields by a metal free diazo-transfer reaction using 2-azido-1,3-dimethylimidazolinium hexafluorophosphate (ADMP), which is safe and stable crystalline. The choice of base was important in the diazo-transfer reaction. In general, 4-(N,N-dimethyl)aminopyridine (DMAP) was efficient, but a stronger base such as alkylamine or DBU was more appropriate for the reaction of nucleophilic primary amines. X-ray single crystal structural analysis and geometry optimization using density functional theory (B3LYP/6-31G**) were conducted to study the ADMP structure, and the diazo-transfer reaction mechanism was explained with the help of the results of these analyses.

  14. Annual progress report : for the period of January 2001 through December 2001 : Florida Transit Training Program (2001) : Florida Technical Assistance Program (2001)

    DOT National Transportation Integrated Search

    2001-01-01

    The following progress report is intended to highlight the significant activities of the Florida Transit Training Program and Florida Technical Assistant Program for the 2001 year. Activities of the Florida Statewide Transit Training Program are pres...

  15. Selling Technical Sales to Engineering Learners

    ERIC Educational Resources Information Center

    Bumblauskas, Daniel P.; Carberry, Adam R.; Sly, David P.

    2017-01-01

    Sales engineering or technical sales programs bridge engineering and business to educate engineering students in sales specific to their discipline. Students develop business awareness through such programs, providing the sales workforce with technically knowledgeable salespeople. The following study analyzed cohorts of students enrolled in a…

  16. TADS Needs Assessment Procedures Manual, Summer 1980.

    ERIC Educational Resources Information Center

    Black, Talbot; And Others

    The TADS (Technical Assistance Development System) Needs Assessment Manual is designed to guide the comprehensive review of Handicapped Children's Early Education Program (HCEEP) demonstration projects in identifying technical assistance needs. An introduction reviews the TADS technical assistance model which includes program planning, needs…

  17. 10 CFR 455.121 - Grant applications for State technical assistance, program assistance, and marketing programs.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... costs for such program; (4) The energy conservation measures funded from non-Federal sources under this... non-Federal sources of funding to carry out the State's program(s) for energy conservation measures... 10 Energy 3 2010-01-01 2010-01-01 false Grant applications for State technical assistance, program...

  18. Local Technical Assistance Program Field Manual

    DOT National Transportation Integrated Search

    1997-02-01

    The FHWA Local Technical Assistance Program (LTAP) provides technology transfer products to local highway departments. One of the most valuable and well-received resources of the program, the LTAP (or T 2 ) centers, have proven themselves invaluable ...

  19. 75 FR 61121 - Trade Adjustment Assistance for Farmers

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-04

    ... program, may apply for technical training and cash benefits by completing and submitting a written... technical assistance training under the program in order to be eligible for cash benefits. Producers.... After submitting a completed application, producers may receive technical assistance at no cost and cash...

  20. 77 FR 60140 - Notice of Proposed Information Collection; Request for Comments

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-02

    ... renewed approval for the collection of information for two technical training program course effectiveness... of information contained in two technical training program course effectiveness evaluation forms. OSM... days in which to comment on the following information collection activities: Title: Technical Training...

  1. THE OFFICE OF AEROSPACE RESEARCH SCIENTIFIC AND TECHNICAL INFORMATION PROGRAM

    DTIC Science & Technology

    The document outlines the mission and organization of the Office of Aerospace Research (OAR), then describes how its principal product, scientific...effective technical information program, are documented by examples. The role of the Office of Scientific and Technical Information within OAR as performed

  2. An evaluation of client satisfaction with training programs and technical assistance provided by Florida's Coordinated School Health Program Office.

    PubMed

    Weiler, R M; Pigg, R M

    2000-11-01

    Client or customer satisfaction surveys assess the perceived quality of programs, products, services, and employee performance. Such assessments prove beneficial for evaluation and planning purposes. This survey examined the satisfaction of clients using the programs, services, and technical assistance provided through the Coordinated School Health Program Office (CSHPO) in the Florida Department of Education. Using the 42-item Client Satisfaction Survey, data were collected in summer 1999 from 300 of 574 clients (52.3%) who attended training sessions or sought technical assistance from CSHPO during 1996-1999. More than two-thirds (67.2%) of clients rated the training program as "very good" or "excellent" at increasing their understanding about the concept of a coordinated school health program. Overall, 69.7% of clients rated the training programs they attended as "very good" or "excellent." Resource materials and staff effectiveness rated positively as well. Findings confirmed client satisfaction with CSHPO's training programs, technical assistance, and staff. Information obtained through the client satisfaction survey can be used by CSHPO to assist in future program planning and resource allocations.

  3. 76 FR 24917 - Notice of Funding Opportunity and Solicitation for Grant Applications (SGA) for H-1B Technical...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-03

    ... Solicitation for Grant Applications (SGA) for H-1B Technical Skills Training Grants AGENCY: Employment and... million in funds for an H-1B Technical Skills Training Grants program. This grant program is designed to... training. H-1B technical skills training grants are financed by a user fee paid by employers to bring...

  4. A Review and Evaluation of the Langley Research Center's Scientific and Technical Information Program. Results of Phase VI-The Technical Report: A Survey and Analysis.

    ERIC Educational Resources Information Center

    McCullough, Robert A.; And Others

    This report presents the results of a review and evaluation of the Langley Research Center's scientific and technical information program, which examined technical reports from various institutions and organizations to determine the organization of reports, the language used to convey information, and the methods used to present information.…

  5. Teaching Leadership in Technical Programs at Community Colleges

    ERIC Educational Resources Information Center

    DeBlauw, Amanda L.; Daugherty, Jenny L.

    2017-01-01

    This descriptive study explored how community colleges are teaching leadership in technical programs. Leadership education curricular offerings were identified via a survey and selected programs reviewed. 68 Deans, Directors, or Chairpersons of a Business, Management, or Technology program completed the survey, representing 61 community colleges.…

  6. Vocational Teacher Education at Ferris State College: Product of Constant Evaluation and Revision

    ERIC Educational Resources Information Center

    Storm, George

    1974-01-01

    The trade-technical education program at Ferris State College, Big Rapids, Michigan, is reviewed. The curriculum of the college, its intern programs, and the teacher preparation technical programs are described. (DS)

  7. Cooperative and Concurrent Enrollment and College Retention

    ERIC Educational Resources Information Center

    Foster, Regina

    2010-01-01

    Oklahoma has a unique system of high schools, technology centers and community colleges that work together to enable students to receive education in technical areas. Given Oklahoma's shortage of technical degree recipients, the Cooperative Alliance Program (CAP) was developed to encourage additional students to begin technical programs during…

  8. 25 CFR 170.170 - How are Indian LTAP centers managed?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... ROADS PROGRAM Indian Reservation Roads Program Policy and Eligibility Indian Local Technical Assistance... Center Director and staff, with the advice of its technical panel under the Indian LTAP agreements. FHWA... technical panel consisting of one BIA Regional Road Engineer, one FHWA representative, one state DOT...

  9. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Green, D.W.; Heinrich, R.R.; Jensen, K.J.

    Technical and administrative activities of the Analytical Chemistry Laboratory (ACL) are reported for fiscal year 1984. The ACL is a full-cost-recovery service center, with the primary mission of providing a broad range of technical support services to the scientific and engineering programs at ANL. In addition, ACL conducts a research program in analytical chemistry, works on instrumental and methods development, and provides analytical services for governmental, educational, and industrial organizations. The ACL is administratively within the Chemical Technology Division, the principal user, but provides technical support for all of the technical divisions and programs at ANL. The ACL has threemore » technical groups - Chemical Analysis, Instrumental Analysis, and Organic Analysis. Under technical activities 26 projects are briefly described. Under professional activities, a list is presented for publications and reports, oral presentations, awards and meetings attended. 6 figs., 2 tabs.« less

  10. An analysis of the technical status of high level radioactive waste and spent fuel management systems

    NASA Technical Reports Server (NTRS)

    English, T.; Miller, C.; Bullard, E.; Campbell, R.; Chockie, A.; Divita, E.; Douthitt, C.; Edelson, E.; Lees, L.

    1977-01-01

    The technical status of the old U.S. mailine program for high level radioactive nuclear waste management, and the newly-developing program for disposal of unreprocessed spent fuel was assessed. The method of long term containment for both of these waste forms is considered to be deep geologic isolation in bedded salt. Each major component of both waste management systems is analyzed in terms of its scientific feasibility, technical achievability and engineering achievability. The resulting matrix leads to a systematic identification of major unresolved technical or scientific questions and/or gaps in these programs.

  11. Final report : for the period of December 1999 through November 30, 2000 : Florida Transit Training Program (1999/2000) : Florida Technical Assistance Program (1999/2000)

    DOT National Transportation Integrated Search

    2000-01-01

    The following progress report is intended to highlight the significant activities of the Florida Transit Training Program and Florida Technical Assistant Program. The following progress report is intended to highlight the significant activities of th...

  12. 25 CFR 547.13 - What are the minimum technical standards for program storage media?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... storage media? 547.13 Section 547.13 Indians NATIONAL INDIAN GAMING COMMISSION, DEPARTMENT OF THE INTERIOR... the minimum technical standards for program storage media? (a) Removable program storage media. All removable program storage media must maintain an internal checksum or signature of its contents...

  13. 25 CFR 547.13 - What are the minimum technical standards for program storage media?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... storage media? 547.13 Section 547.13 Indians NATIONAL INDIAN GAMING COMMISSION, DEPARTMENT OF THE INTERIOR... the minimum technical standards for program storage media? (a) Removable program storage media. All removable program storage media must maintain an internal checksum or signature of its contents...

  14. Blackhawk Technical College Alcohol and Other Drug Abuse Program.

    ERIC Educational Resources Information Center

    Runnells, Julie

    This document describes the Blackhawk Technical College, Wisconsin, drug abuse program provided primarily by an intervention specialist and available to students and employees. Section I outlines the program model (resources, program of services, immediate results and outcomes) in a chart form. Section II describes the services provided by an…

  15. 48 CFR 227.7104 - Contracts under the Small Business Innovation Research (SBIR) Program.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Business Innovation Research (SBIR) Program. 227.7104 Section 227.7104 Federal Acquisition Regulations... Innovation Research (SBIR) Program. (a) Use the clause at 252.227-7018, Rights in Noncommercial Technical Data and Computer Software—Small Business Innovation Research (SBIR) Program, when technical data or...

  16. 48 CFR 227.7104 - Contracts under the Small Business Innovation Research (SBIR) Program.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Business Innovation Research (SBIR) Program. 227.7104 Section 227.7104 Federal Acquisition Regulations... Innovation Research (SBIR) Program. (a) Use the clause at 252.227-7018, Rights in Noncommercial Technical Data and Computer Software—Small Business Innovation Research (SBIR) Program, when technical data or...

  17. 48 CFR 227.7104 - Contracts under the Small Business Innovation Research (SBIR) Program.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Business Innovation Research (SBIR) Program. 227.7104 Section 227.7104 Federal Acquisition Regulations... Innovation Research (SBIR) Program. (a) Use the clause at 252.227-7018, Rights in Noncommercial Technical Data and Computer Software—Small Business Innovation Research (SBIR) Program, when technical data or...

  18. 75 FR 32858 - Medicare Program; Policy and Technical Changes to the Medicare Advantage and the Medicare...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-10

    ... Medicare Advantage and the Medicare Prescription Drug Benefit Programs; Corrections AGENCY: Centers for... Advantage and the Medicare Prescription Drug Benefit Programs'' which appeared in the April 15, 2010 Federal... and Technical Changes to the Medicare Advantage and the Medicare Prescription Drug Benefit Programs...

  19. Women and Technical Professions. Leonardo da Vinci Series: Good Practices.

    ERIC Educational Resources Information Center

    Commission of the European Communities, Brussels (Belgium). Directorate-General for Education and Culture.

    This document profiles programs for women in technical professions that are offered through the European Commission's Leonardo da Vinci program. The following programs are profiled: (1) Artemis and Diana (vocational guidance programs to help direct girls toward technology-related careers); (2) CEEWIT (an Internet-based information and…

  20. Maintaining Strategic Relevance: Career & Technical Education Program Discontinuance within California Community Colleges

    ERIC Educational Resources Information Center

    Fleming, Kevin J.

    2014-01-01

    The California Community College mission requires offering relevant Career and Technical Education (CTE) programs. Due to program accretion and bureaucratic inertia, program discontinuance (PD) seems at odds with postsecondary culture. Yet, as a result of recent budget constrictions, community colleges are forced to identify effective PD…

  1. 15 CFR 295.11 - Technical and educational services for ATP recipients.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Foreign Trade NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY, DEPARTMENT OF COMMERCE NIST EXTRAMURAL PROGRAMS ADVANCED TECHNOLOGY PROGRAM General § 295.11 Technical and educational services for ATP recipients... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Technical and educational services for...

  2. 76 FR 2147 - UAW-Chrysler National Training Center Technology Training Joint Programs Staff, Detroit, MI; UAW...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-12

    ... Technical Training Center Technology Training Joint Programs Staff, Warren, MI; Notice of Revised... facilities. The information revealed that the technical training provided (such as applied industrial... engaged in employment related to the supply of technical training services, meet the worker group...

  3. 76 FR 33332 - Announcement of Funding Awards for the Technical Assistance and Capacity Building under the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-08

    ... of key Departmental objectives, including but not limited to, energy efficiency and green building... Awards for the Technical Assistance and Capacity Building under the Transformation Initiative Program...) for the Technical Assistance and Capacity Building under the Transformation Initiative program for...

  4. Vocational-Technical Education: A Plan for Monroe County, Florida.

    ERIC Educational Resources Information Center

    Mills, Hugh L., Sr., Ed.; Pilcher, Palmer, C., Ed.

    Suggested vocational-technical education programs for the Monroe County Florida school system are presented along with recommendations to implement the principle of coordinated career education in the public schools. Expansion of vocational-technical programs is emphasized to expose all students from kindergarten through Grade 12 to career…

  5. 75 FR 19297 - Energy Conservation Program: Public Meeting and Availability of the Preliminary Technical Support...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-14

    ... Conservation Program: Public Meeting and Availability of the Preliminary Technical Support Document for Walk-In... and availability of the preliminary technical support document regarding energy conservation standards..., the deadline for requesting to speak at the public meeting, and the deadline for submitting written...

  6. 75 FR 9608 - National Protection and Programs Directorate; Technical Assistance Request and Evaluation

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-03

    ... Directorate; Technical Assistance Request and Evaluation AGENCY: National Protection and Programs Directorate... assistance requests from each State and territory. OEC will use the Technical Assistance Evaluation Form to... electronically. Evaluation forms may be submitted electronically or in paper form. The Office of Management and...

  7. Preparing Workforce 2000 through Vocational Technical 2+2 Programs.

    ERIC Educational Resources Information Center

    Portland Area Vocational-Technical Education Consortium, OR.

    An overview is provided of the 1989 accomplishments of the Portland Area Vocational Technical Education Consortium (PAVTEC), which was created to strengthen partnerships between Portland Community College (PCC) and local high schools to provide high quality articulated vocational-technical programs. The first section looks at the roles of PAVTEC,…

  8. 40 CFR 52.744 - Small business stationary source technical and environmental compliance assistance program.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 3 2010-07-01 2010-07-01 false Small business stationary source technical and environmental compliance assistance program. 52.744 Section 52.744 Protection of Environment... PLANS Illinois> § 52.744 Small business stationary source technical and environmental compliance...

  9. 40 CFR 52.798 - Small business stationary source technical and environmental compliance assistance program.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 3 2010-07-01 2010-07-01 false Small business stationary source technical and environmental compliance assistance program. 52.798 Section 52.798 Protection of Environment... PLANS Indiana § 52.798 Small business stationary source technical and environmental compliance...

  10. An Overview of Clarkson's Technical Communications Program.

    ERIC Educational Resources Information Center

    Barkman, Patricia R.

    The technical communications program at Clarkson College (New York) offers students 23 courses in subjects ranging from interpersonal behavior to engineering and scientific report writing to computer documentation and the development of technical manuals. With the help of an advisor, each student works out a course of study appropriate to his or…

  11. An Analysis of National Surveys: Associate Degree Programs in Manufacturing Engineering and Related Programs. A Preliminary Report.

    ERIC Educational Resources Information Center

    Mathias, Elizabeth A.

    In 1993, a study was conducted to investigate the responses of associate degree programs in manufacturing and related technical programs to current technical education initiatives. The study focused on the relationships of associate degree programs to secondary and postsecondary education and industry, curricular trends, familiarity with the…

  12. Evaluation of the Radiography Program at Caldwell Community College and Technical Institute--Summer, 1982.

    ERIC Educational Resources Information Center

    Pipes, V. David

    As part of a periodic evaluation of the occupational programs at Caldwell Community College and Technical Institute (CCC&TI), a study of the radiography program was conducted to collect information to facilitate planning, aid in program improvement, and meet accountability demands. The specific objectives of the program evaluation were to…

  13. Curriculum Programs in Action, Their Administration and Evaluation; Report of a Conference Devoted to Description, Demonstration, and Evaluative Discussions of Innovative Programs in Vocational-Technical Education.

    ERIC Educational Resources Information Center

    San Francisco State Coll., CA. Center for Technological Education.

    The presentation, review and evaluation of innovative vocational-technical curriculums in operation was the major function of a San Francisco conference sponsored jointly by the Center for Technical Education at San Francisco State College and the Center for Studies in Vocational and Technical Education at the University of Wisconsin. Major…

  14. NASA Engineering Excellence: A Case Study on Strengthening an Engineering Organization

    NASA Technical Reports Server (NTRS)

    Shivers, C. Herbert; Wessel, Vernon W.

    2006-01-01

    NASA implemented a system of technical authority following the Columbia Accident Investigation Board (CAE) report calling for independent technical authority to be exercised on the Space Shuttle Program activities via a virtual organization of personnel exercising specific technical authority responsibilities. After the current NASA Administrator reported for duty, and following the first of two planned "Shuttle Return to Flight" missions, the NASA Chief Engineer and the Administrator redirected the Independent Technical Authority to a program of Technical Excellence and Technical Authority exercised within the existing engineering organizations. This paper discusses the original implementation of technical authority and the transition to the new implementation of technical excellence, including specific measures aimed at improving safety of future Shuttle and space exploration flights.

  15. U.S. Air Force Scientific and Technical Information Program - The STINFO Program

    NASA Technical Reports Server (NTRS)

    Blados, Walter R.

    1991-01-01

    The U.S. Air Force STINFO (Scientific and Technical Information) program has as its main goal the proper use of all available scientific and technical information in the development of programs. The organization of STINFO databases, the use of STINFO in the development and advancement of aerospace science and technology and the acquisition of superior systems at lowest cost, and the application to public and private sectors of technologies developed for military uses are examined. STINFO user training is addressed. A project for aerospace knowledge diffusion is discussed.

  16. STEM integration in middle school career and technical education programs: A Delphi design study

    NASA Astrophysics Data System (ADS)

    Wu-Rorrer, Billy Ray

    The purpose of this qualitative method study with a Delphi research design sought to determine how STEM programs can be effectively integrated into middle school career and technical education programs by local, state, and national educators, administrators, directors, specialists, and curriculum writers. The significance of the study is to provide leaders in CTE with a greater awareness, insight, and strategies about how CTE programs can more effectively integrate academics into career and technical education programs through STEM-related programming. The findings will increase the limited amount of available literature providing best practice strategies for the integration of STEM curriculum into middle school CTE programs. One basic question has guided this research: How can STEM programs be effectively integrated into middle school career and technical education programs? A total of twelve strategies were identified. The strategies of real-world applications and administrative buy-in were the two predominant strategies consistently addressed throughout the review of literature and all three sub-questions in the research study. The Delphi design study consisted of pilot round and three rounds of data collection on barriers, strategies, and professional development for STEM integration in middle school career and technical education programs. Four panelists participated in the pilot round, and 16 panel members not involved in the pilot round participated in the three rounds of questioning and consensus building. In the future, more comprehensive studies can build upon this foundational investigation of middle school CTE programs.

  17. 77 FR 37284 - Technical Amendments

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-21

    ... DEPARTMENT OF LABOR Office of Workers' Compensation Programs 20 CFR Parts 701, 702, 703, 725, and 726 RIN 1240-AA05 Technical Amendments AGENCY: Office of Workers' Compensation Programs, Labor. ACTION: Final rule. SUMMARY: The Office of Workers' Compensation Programs is making [[Page 37285

  18. Solid Waste Program technical baseline description

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Carlson, A.B.

    1994-07-01

    The system engineering approach has been taken to describe the technical baseline under which the Solid Waste Program is currently operating. The document contains a mission analysis, function analysis, system definition, documentation requirements, facility and project bases, and uncertainties facing the program.

  19. Technical Excellence: A Requirement for Good Engineering

    NASA Technical Reports Server (NTRS)

    Gill, Paul S.; Vaughan, William W.

    2008-01-01

    Technical excellence is a requirement for good engineering. Technical excellence has many different ways of expressing itself within engineering. NASA has initiatives that address the enhancement of the Agency's technical excellence and thrust to maintain the associated high level of performance by the Agency on current programs/projects and as it moves into the Constellation Program and the return to the Moon with plans to visit Mars. This paper addresses some of the key initiatives associated with NASA's technical excellence thrust. Examples are provided to illustrate some results being achieved and plans to enhance these initiatives.

  20. From Industry to Teaching: The Quality Instruction Program at Hocking Technical College.

    ERIC Educational Resources Information Center

    Moran, Ralph; And Others

    This presentation on Hocking Technical College's (HTC's) Quality Instruction Program (QIP) provides a program description and comments from three HTC faculty members who have been involved in the program in various ways. Recognizing that many faculty members are hired on the basis of their industrial credentials rather than their teaching…

  1. Report on Occupational/Technical Programs at Piedmont Virginia Community College. Research Report No. 2-96.

    ERIC Educational Resources Information Center

    Head, Ronald B.

    Part of an annual review of occupational/technical programs at Piedmont Virginia Community College (PVCC), this report describes enrollment, graduation, and placement outcomes for PVCC's Associate of Applied Science and certificate programs. Following an executive summary and introduction, the report presents data on program outcomes related to…

  2. 48 CFR 301.607-78 - Contracting Officer designation of a Program/Project Manager as the Contracting Officer's...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... designation of a Program/Project Manager as the Contracting Officer's Technical Representative. 301.607-78... Contracting Officer designation of a Program/Project Manager as the Contracting Officer's Technical... acquisition. However, for those individuals serving as a Program or Project Manager under a FAC-P/PM...

  3. 75 FR 47573 - Career and Technical Education Program-Promoting Rigorous Career and Technical Education Programs...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-06

    ... program is to use 10 key components based on the ``Program of Study Design Framework'' [[Page 47574...., the States' Career Clusters \\2\\), and offer students the opportunities to earn postsecondary credits... extent to which students are attaining necessary knowledge and skills, we agree that administrators...

  4. 78 FR 43091 - Technical Operations Safety Action Program (T-SAP) and Air Traffic Safety Action Program (ATSAP)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-19

    ... Administration 14 CFR Part 193 [Docket No.: FAA-2013-0375] Technical Operations Safety Action Program (T-SAP) and Air Traffic Safety Action Program (ATSAP) AGENCY: Federal Aviation Administration (FAA), Department of Transportation (DOT). ACTION: Notice of Proposed Order Designating Safety Information as Protected from...

  5. A Comprehensive Review of Selected Business Programs in Community Colleges and Area Vocational-Technical Centers. Program Review Report.

    ERIC Educational Resources Information Center

    Florida State Dept. of Education, Tallahassee. Div. of Vocational, Adult, and Community Education.

    In 1988, a review was conducted of the business component of associate in arts and associate in science (AS) degree programs, and of the certificate programs in business in Florida community colleges and area vocational-technical centers. Focusing primarily on business programs in marketing, general business management, and small business…

  6. Texas Higher Education Coordinating Board 2000 Statewide Annual Licensure Report.

    ERIC Educational Resources Information Center

    Texas Higher Education Coordinating Board, Austin. Div. of Community and Technical Colleges.

    This report provides the licensure examination results for two-year technical associate degrees and one-year certificate programs at community and technical colleges in Texas. The Texas Higher Education Coordinating Board recognizes the success rate for licensure as an integral part of the overall success of many technical programs. The following…

  7. Instrument and Survey Analysis Technical Report: Program Implementation Survey. Technical Report #1112

    ERIC Educational Resources Information Center

    Alonzo, Julie; Tindal, Gerald

    2011-01-01

    This technical document provides guidance to educators on the creation and interpretation of survey instruments, particularly as they relate to an analysis of program implementation. Illustrative examples are drawn from a survey of educators related to the use of the easyCBM learning system. This document includes specific sections on…

  8. User Problems Associated with the Services of Federal and Quasi-Federal Technical Information Producing Agencies.

    ERIC Educational Resources Information Center

    Los Angeles Regional Technical Information Users Council, CA.

    Nine reports of the Los Angeles Regional Technical Information Users Council, which identify and discuss user problem areas and recommend solutions, comprise this document. The topics of the reports are: (1) Air Force Technical Objective Document Release Program (AFTOD); (2) Army Qualitative Requirements Information Program (QDRI); (3)…

  9. Programs of Study: Year 2 Joint Technical Report. Research Snapshot

    ERIC Educational Resources Information Center

    National Research Center for Career and Technical Education, 2010

    2010-01-01

    In January 2010, the National Research Center for Career and Technical Education (NRCCTE) issued a progress report on three studies being conducted by the Center that examine the implementation and outcomes of Programs of Study (POS), which were required in the 2006 reauthorization of the federal legislation for career and technical education…

  10. National Evaluation of the IDEA Technical Assistance & Dissemination Program. NCEE 2014-4000

    ERIC Educational Resources Information Center

    Daley,Tamara C.; Fiore, Thomas A.; Bollmer, Julie; Nimkoff, Tamara; Lysy, Chris

    2013-01-01

    Under the Individuals with Disabilities Education Act (IDEA), the Technical Assistance and Dissemination (TA&D) Program is the U.S. Department of Education's (ED) primary vehicle for providing technical assistance (TA) to individuals and organizations responsible for serving children with disabilities and their families. The evaluation is part…

  11. Technical and Vocational Education and Training in Peace Education: Solomon Islands

    ERIC Educational Resources Information Center

    Maebuta, Jack

    2011-01-01

    Technical and vocational education and training programs as a form of peace education are examined in this paper. It explores the notion of educating for a culture of peace through refocusing technical and vocational education and training programs on sustainable community development in the Solomon Islands. It further highlights the policy and…

  12. 77 FR 34354 - Notice Inviting Informal Public Comment on Training and Technical Assistance and Disability...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-11

    ... and Technical Assistance and Disability Inclusion Programming AGENCY: Corporation for National and... implementation of a unified training and technical assistance (TTA) strategy and disability inclusion programming... to CNCS as we plan and prepare for this work. We will accept comments in writing, as described below...

  13. Technical Communication Internship Requirements in the Academic Economy: How We Compare among Ourselves and across Other Applied Fields

    ERIC Educational Resources Information Center

    Savage, Gerald J.; Seible, Marcea K.

    2010-01-01

    This article reports a study of internship requirements in technical communication programs compared with three established professions and one emerging profession that have certification or licensing requirements for practitioners. The study addresses three questions about technical communication internship programs: 1) Are internships offered as…

  14. An Analysis of Gateway Technical College Instructors' Opinions on Secondary and Postsecondary Program Alignment

    ERIC Educational Resources Information Center

    Albrecht, Bryan D.

    2011-01-01

    The purpose of this study was to determine what opinions Gateway Technical College instructors had toward secondary and postsecondary program alignment. Student transition is critical to supporting the mission and vision of Gateway Technical College. The impetus for this study was twofold. First, the quality improvement process established at…

  15. Connections for the Future through Vocational Technical 2 + 2 Programs. Annual Report, April 1989.

    ERIC Educational Resources Information Center

    Portland Area Vocational-Technical Education Consortium, OR.

    The Portland Area Vocational Technical Education Consortium (PAVTEC) was created to enhance and strengthen the working partnerships between Portland Community College and local high schools in order to provide high quality, articulated vocational technical programs. PAVTEC's third annual report highlights activities which have added to the…

  16. A National Survey on Teaching and Assessing Technical Proficiency in Vascular Surgery in Canada.

    PubMed

    Drudi, Laura; Hossain, Sajjid; Mackenzie, Kent S; Corriveau, Marc-Michel; Abraham, Cherrie Z; Obrand, Daniel I; Vassiliou, Melina; Gill, Heather; Steinmetz, Oren K

    2016-05-01

    This survey aims to explore trainees' perspectives on how Canadian vascular surgery training programs are using simulation in teaching and assessing technical skills through a cross-sectional national survey. A 10-min online questionnaire was sent to Program Directors of Canada's Royal College of Physicians and Surgeons' of Canada approved training programs in vascular surgery. This survey was distributed among residents and fellows who were studying in the 2013-2014 academic year. Twenty-eight (58%) of the 48 Canadian vascular surgery trainees completed the survey. A total of 68% of the respondents were part of the 0 + 5 integrated vascular surgery training program. The use of simulation in the assessment of technical skills at the beginning of training was reported by only 3 (11%) respondents, whereas 43% reported that simulation was used in their programs in the assessment of technical skills at some time during their training. Training programs most often provided simulation as a method of teaching and learning endovascular abdominal aortic or thoracic aneurysm repair (64%). Furthermore, 96% of trainees reported the most common resource to learn and enhance technical skills was dialog with vascular surgery staff. Surveyed vascular surgery trainees in Canada report that simulation is rarely used as a tool to assess baseline technical skills at the beginning of training. Less than half of surveyed trainees in vascular surgery programs in Canada report that simulation is being used for skills acquisition. Currently, in Canadian training programs, simulation is most commonly used to teach endovascular skills. Copyright © 2016 Elsevier Inc. All rights reserved.

  17. 10 CFR 455.90 - Purpose.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Marketing § 455.90 Purpose. This subpart describes what constitutes a State program for technical assistance, program assistance, and marketing that may receive financial assistance under this part and sets forth the eligibility criteria for States to receive grants for technical assistance, program assistance, and marketing. ...

  18. IAC - INTEGRATED ANALYSIS CAPABILITY

    NASA Technical Reports Server (NTRS)

    Frisch, H. P.

    1994-01-01

    The objective of the Integrated Analysis Capability (IAC) system is to provide a highly effective, interactive analysis tool for the integrated design of large structures. With the goal of supporting the unique needs of engineering analysis groups concerned with interdisciplinary problems, IAC was developed to interface programs from the fields of structures, thermodynamics, controls, and system dynamics with an executive system and database to yield a highly efficient multi-disciplinary system. Special attention is given to user requirements such as data handling and on-line assistance with operational features, and the ability to add new modules of the user's choice at a future date. IAC contains an executive system, a data base, general utilities, interfaces to various engineering programs, and a framework for building interfaces to other programs. IAC has shown itself to be effective in automatic data transfer among analysis programs. IAC 2.5, designed to be compatible as far as possible with Level 1.5, contains a major upgrade in executive and database management system capabilities, and includes interfaces to enable thermal, structures, optics, and control interaction dynamics analysis. The IAC system architecture is modular in design. 1) The executive module contains an input command processor, an extensive data management system, and driver code to execute the application modules. 2) Technical modules provide standalone computational capability as well as support for various solution paths or coupled analyses. 3) Graphics and model generation interfaces are supplied for building and viewing models. Advanced graphics capabilities are provided within particular analysis modules such as INCA and NASTRAN. 4) Interface modules provide for the required data flow between IAC and other modules. 5) User modules can be arbitrary executable programs or JCL procedures with no pre-defined relationship to IAC. 6) Special purpose modules are included, such as MIMIC (Model Integration via Mesh Interpolation Coefficients), which transforms field values from one model to another; LINK, which simplifies incorporation of user specific modules into IAC modules; and DATAPAC, the National Bureau of Standards statistical analysis package. The IAC database contains structured files which provide a common basis for communication between modules and the executive system, and can contain unstructured files such as NASTRAN checkpoint files, DISCOS plot files, object code, etc. The user can define groups of data and relations between them. A full data manipulation and query system operates with the database. The current interface modules comprise five groups: 1) Structural analysis - IAC contains a NASTRAN interface for standalone analysis or certain structural/control/thermal combinations. IAC provides enhanced structural capabilities for normal modes and static deformation analysis via special DMAP sequences. IAC 2.5 contains several specialized interfaces from NASTRAN in support of multidisciplinary analysis. 2) Thermal analysis - IAC supports finite element and finite difference techniques for steady state or transient analysis. There are interfaces for the NASTRAN thermal analyzer, SINDA/SINFLO, and TRASYS II. FEMNET, which converts finite element structural analysis models to finite difference thermal analysis models, is also interfaced with the IAC database. 3) System dynamics - The DISCOS simulation program which allows for either nonlinear time domain analysis or linear frequency domain analysis, is fully interfaced to the IAC database management capability. 4) Control analysis - Interfaces for the ORACLS, SAMSAN, NBOD2, and INCA programs allow a wide range of control system analyses and synthesis techniques. Level 2.5 includes EIGEN, which provides tools for large order system eigenanalysis, and BOPACE, which allows for geometric capabilities and finite element analysis with nonlinear material. Also included in IAC level 2.5 is SAMSAN 3.1, an engineering analysis program which contains a general purpose library of over 600 subroutin

  19. Perception of Teaching and Assessing Technical Proficiency in American College of Veterinary Surgeons Small Animal Surgery Residency Programs.

    PubMed

    Kim, Stanley E; Case, J Brad; Lewis, Daniel D; Ellison, Gary W

    2015-08-01

    To determine how American College of Veterinary Surgeons (ACVS) small animal surgery residency programs are teaching and assessing technical skills, and ascertain the perceived value of those methods. Internet-based survey. Residents and Diplomate supervisors of ACVS small animal residency programs. Residents and supervisors were surveyed on their experience of surgery instruction, use of different resources for teaching, type and frequency of feedback, and perceived effectiveness of their programs in imparting technical proficiency. A total of 130 residents (62%) and 119 supervisors (44%) participated. Both residents and supervisors estimated the resident was the primary surgeon for a mean of 64% of cases, although this proportion varied widely between participants. The majority of residents and supervisors considered that direct intraoperative guidance was the most effective way for residents to develop technical skills. Verbal interactions between supervisor and resident occurred frequently and were highly valued. Regular wet laboratories and access to simulation models were uncommon. Despite over 90% of all participants reporting that a sufficient level of technical aptitude would be attained, only 58% of residents were satisfied with their technical skills training. Residents relied on direct interaction with supervisors to develop technical skills. The traditional mode of instruction for veterinary residents is the apprenticeship model, which is partly driven by ACVS requirements of supervisory support. Exposure to other teaching and assessment methods was variable. The current structure of residency programs is successful in imparting technical competency as perceived by supervisors and residents. However, consideration of a more formal method of residency training with structured assessment of technical skills as in human medicine should not be dismissed. © Copyright 2015 by The American College of Veterinary Surgeons.

  20. The Two-Year Colleges' Role in Building the Future Geoscience Technical Workforce

    NASA Astrophysics Data System (ADS)

    Wolfe, B.

    2014-12-01

    Careers in energy science related fields represent significant job growth in the U.S. Yet post-secondary career and technical programs have not kept pace with demand and energy science curriculum, including fundamental concepts of energy generation and environmental impact, lacks a firm position among general or career and technical education courses. Many of these emerging energy related jobs are skilled labor and entry level technical positions requiring less than a bachelor's degree. These include jobs such as solar/photovoltaic design and installation, solar water and space heating installation, energy management, efficiency and conservation auditor, environmental technician, etc. These energy related career pathways fit naturally within the geosciences discipline. Many of these jobs can be filled by individuals from HVAC, Industrial technology, welding, and electrical degree programs needing some additional specialized training and curriculum focused on fundamental concepts of energy, fossil fuel exploration and use, atmospheric pollution, energy generation, alternative energy sources, and energy conservation. Two-year colleges (2ycs) are uniquely positioned to train and fill these workforce needs as they already have existing career and technical programs and attract both recent high school graduates, as well as non-traditional students including displaced workers and returning veterans. We have established geoscience related workforce certificate programs that individuals completing the traditional industrial career and technical degrees can obtain to meet these emerging workforce needs. This presentation will discuss the role of geosciences programs at 2ycs in training these new workers, developing curriculum, and building a career/technical program that is on the forefront of this evolving industry.

  1. Predictions of Performance in Career Education.

    ERIC Educational Resources Information Center

    Novick, M. R.; And Others

    Prediction weights for educational programs in 22 vocational and technical fields are provided using ability scores from the American College Testing Program (ACT) Career Planning Profile and a Bayesian regression theory. The criterion variable studies was first-semester grade-point average. Each vocational-technical program analyzed was…

  2. Assessment Program Technical Progress Report, 1996-1997.

    ERIC Educational Resources Information Center

    McCown, Laurie; Fanning, Erin; Eickmeyer, Barbara

    Coconino Community College (CCC) annually assesses its institutional effectiveness to demonstrate its commitment to improving programs and services to students. The 1996-97 Assessment Program Technical Progress Report records the assessment and institutional activities enacted during the academic year, detailing the assessment model, timelines,…

  3. Conduct of a Survey to Determine Why Blacks Do Not Have Sufficient Enrollment in Vocational-Technical Programs in Community Colleges, Area Vocational-Technical Centers and Secondary Schools, and Development of Strategies for Increasing the Number of Students Enrolling in Vocational-Technical Programs.

    ERIC Educational Resources Information Center

    West Virginia Research Coordinating Unit for Vocational Education, Huntington.

    A project involving literature and demographic data reviews, survey development, survey administration, data analysis, and document preparation was conducted in West Virginia to determine why blacks do not have sufficient enrollments in vocational technical centers and secondary schools. Three separate multiple-choice questionnaires were developed…

  4. USAF/SCEEE Graduate Student Summer Support Program (1982). Management and Technical Report.

    DTIC Science & Technology

    1982-10-01

    AD-A130 767 USAF/SCEEE GRADUATE STUDENT SUMMER SUPPORT PROGRAM (1982) MANAGEMENT AND..(U) SOUTHEASTERN CENTER FORELECTRICAL ENGINEERING EDUCATION INC...SUMMER SUPPORT PROGRAM Conducted by Southeastern Center for Electrical Engineering Education under USAF Contract Number F49620-82-C-0035 MANAGEMENT ...UNITED STATES AIR FORCE GRADUATE STUDENT SL24MER SUPPORT PROGRAM 1982 PROGRAM MANAGEMENT AND TECHNICAL REPORT SOUTHEASTERN CENTER FOR ELECTRICAL

  5. 10 CFR 455.144 - Grant awards for State programs to provide technical assistance, program assistance, and marketing.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 3 2010-01-01 2010-01-01 false Grant awards for State programs to provide technical assistance, program assistance, and marketing. 455.144 Section 455.144 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION GRANT PROGRAMS FOR SCHOOLS AND HOSPITALS AND BUILDINGS OWNED BY UNITS OF LOCAL GOVERNMENT AND PUBLIC CARE INSTITUTIONS Grant Awards §...

  6. Evaluation of the Industrial Maintenance Program at Caldwell Community College and Technical Institute.

    ERIC Educational Resources Information Center

    Pipes, V. David

    In 1982-83, a study was conducted at Caldwell Community College and Technical Institute to determine whether the objectives of the Industrial Maintenance Program were being met, to measure program success, and to identify aspects needing improvement. Surveys were sent to 30 students who graduated from the program before 1978, yielding a 57%…

  7. Naval Shipyard Apprentice Program & Community-Technical College Linkages: A Model for Success.

    ERIC Educational Resources Information Center

    Cantor, Jeffrey A.

    Each of the eight shipyards operated by the U.S. Navy administers a formal 4-year apprentice trades training program. The apprentice programs combine daily on-the-job training with classroom instruction in technical subjects related to work requirements, including shop math, chemistry, physics, and mechanical drafting. The programs are designed to…

  8. Technical and Professional Communication Programs and the Small College Setting: Opportunities and Challenges

    ERIC Educational Resources Information Center

    Latterell, Catherine G.

    2003-01-01

    This article argues that the small school context has been a relatively unexamined or under-examined context for technical and professional communication program development. While graduate program development holds a large share of the field's attention in recent national forums, growth in graduate programs is a consequence of demand in the job…

  9. Economic Evaluation of Computerized Structural Analysis

    NASA Technical Reports Server (NTRS)

    Fortin, P. E.

    1985-01-01

    This completed effort involved a technical and economic study of the capabilities of computer programs in the area of structural analysis. The applicability of the programs to NASA projects and to other users was studied. The applications in other industries was explored including both research and development and applied areas. The costs of several alternative analysis programs were compared. A literature search covered applicable technical literature including journals, trade publications and books. In addition to the literature search, several commercial companies that have developed computerized structural analysis programs were contacted and their technical brochures reviewed. These programs include SDRC I-DEAS, MSC/NASTRAN, SCADA, SUPERSAP, NISA/DISPLAY, STAAD-III, MICAS, GTSTRUDL, and STARS. These programs were briefly reviewed as applicable to NASA projects.

  10. Internal dosimetry technical basis manual

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1990-12-20

    The internal dosimetry program at the Savannah River Site (SRS) consists of radiation protection programs and activities used to detect and evaluate intakes of radioactive material by radiation workers. Examples of such programs are: air monitoring; surface contamination monitoring; personal contamination surveys; radiobioassay; and dose assessment. The objectives of the internal dosimetry program are to demonstrate that the workplace is under control and that workers are not being exposed to radioactive material, and to detect and assess inadvertent intakes in the workplace. The Savannah River Site Internal Dosimetry Technical Basis Manual (TBM) is intended to provide a technical and philosophicalmore » discussion of the radiobioassay and dose assessment aspects of the internal dosimetry program. Detailed information on air, surface, and personal contamination surveillance programs is not given in this manual except for how these programs interface with routine and special bioassay programs.« less

  11. The Development and Implementation of a School-to-Work Apprenticeship Model at a Technical Career Center.

    ERIC Educational Resources Information Center

    Kraft, James A.

    A business and education partnership model addressed a shortage of local, qualified, entry-level, technically skilled workers through a school-to-work apprenticeship program at the North Montco Technical Career Center in Lansdale, Pennsylvania. The research-based solution plan of the Pennsylvania Youth Apprenticeship Program (PYAP) included three…

  12. 25 CFR 547.13 - What are the minimum technical standards for program storage media?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 2 2011-04-01 2011-04-01 false What are the minimum technical standards for program storage media? 547.13 Section 547.13 Indians NATIONAL INDIAN GAMING COMMISSION, DEPARTMENT OF THE INTERIOR HUMAN SERVICES MINIMUM TECHNICAL STANDARDS FOR GAMING EQUIPMENT USED WITH THE PLAY OF CLASS II GAMES...

  13. 25 CFR 547.13 - What are the minimum technical standards for program storage media?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 2 2010-04-01 2010-04-01 false What are the minimum technical standards for program storage media? 547.13 Section 547.13 Indians NATIONAL INDIAN GAMING COMMISSION, DEPARTMENT OF THE INTERIOR HUMAN SERVICES MINIMUM TECHNICAL STANDARDS FOR GAMING EQUIPMENT USED WITH THE PLAY OF CLASS II GAMES...

  14. 25 CFR 547.13 - What are the minimum technical standards for program storage media?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 25 Indians 2 2012-04-01 2012-04-01 false What are the minimum technical standards for program storage media? 547.13 Section 547.13 Indians NATIONAL INDIAN GAMING COMMISSION, DEPARTMENT OF THE INTERIOR HUMAN SERVICES MINIMUM TECHNICAL STANDARDS FOR GAMING EQUIPMENT USED WITH THE PLAY OF CLASS II GAMES...

  15. Quality Career/Technical Programs Prepare Students to Succeed in a New, More Challenging Economy

    ERIC Educational Resources Information Center

    Southern Regional Education Board (SREB), 2008

    2008-01-01

    Quality career/technical education and its role in school improvement was a primary theme of the 2008 "High Schools That Work" ("HSTW") Staff Development Conference. This newsletter covers crucial topics in quality CTE (career and technical education), including assessing the quality and effectiveness of CT programs, preparing students to succeed…

  16. Towards ESP Programmes in Technical and Vocational Institutions in Malaysia.

    ERIC Educational Resources Information Center

    Shukor, Haji; And Others

    This paper examines the nature of vocational, technical, and polytechnic education in Malaysia, the extent to which English for special purposes (ESP) programs are incorporated into such education, and the need for ESP program reform. In 1992, Malaysia possessed 70 vocational and 9 technical secondary schools, all of which offered some form of ESP…

  17. 75 FR 76468 - Office of the Assistant Secretary for Planning and Evaluation; Medicare Program; Meeting of the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-08

    ... Evaluation; Medicare Program; Meeting of the Technical Advisory Panel on Medicare Trustee Reports AGENCY... announces a public meeting of the Technical Advisory Panel on Medicare Trustee Reports (Panel). Notice of... long run. The Panel's discussion is expected to be very technical in nature and will focus on the...

  18. 77 FR 26553 - Medicare Program; Meeting of the Medicare Economic Index Technical Advisory Panel-May 21, 2012

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-04

    ...] Medicare Program; Meeting of the Medicare Economic Index Technical Advisory Panel--May 21, 2012 AGENCY... announces that a public meeting of the Medicare Economic Index Technical Advisory Panel (``the Panel'') will... Economic Index (MEI). This first meeting will focus on MEI inputs and input weights. This meeting is open...

  19. The Potential of Experiential Learning Models and Practices in Career and Technical Education and Career and Technical Teacher Education

    ERIC Educational Resources Information Center

    Clark, Robert W.; Threeton, Mark D.; Ewing, John C.

    2010-01-01

    Since inception, career and technical education programs have embraced experiential learning as a true learning methodology for students to obtain occupational skills valued by employers. Programs have integrated classroom instruction with laboratory experiences to provide students a significant opportunity to learn. However, it is questionable as…

  20. Government Information Quarterly. Volume 7, no. 2: National Aeronautics and Space Administration Scientific and Technical Information Programs. Special issue

    NASA Technical Reports Server (NTRS)

    Hernon, Peter (Editor); Mcclure, Charles R. (Editor); Pinelli, Thomas E. (Editor)

    1990-01-01

    NASA scientific and technical information (STI) programs are discussed. Topics include management of information in a research and development agency, the new space and Earth science information systems at NASA's archive, scientific and technical information management, and technology transfer of NASA aerospace technology to other industries.

  1. WORKING WITH STUDENTS INSIDE AND OUTSIDE THE CLASSROOM IN ADULT BASIC EDUCATION PROGRAMS.

    ERIC Educational Resources Information Center

    BRAZZIEL, WILLIAM F.

    TECHNICAL EDUCATION OF THE ADULT HARD-CORE UNEMPLOYED OFTEN FAILS BECAUSE OF PERSONAL PROBLEMS AND BASIC EDUCATION AND CULTURAL LACKS. A BROAD CONCEPT OF EDUCATION IS ESSENTIAL TO PROGRAMS FOR DEVELOPMENT OF TECHNICAL SKILLS. A COLLEGE PROJECT DESIGNED TO MEET THESE REQUIREMENTS IS PRESENTED. A COMBINATION OF BASIC AND TECHNICAL EDUCATION WITH THE…

  2. Extensible Markup Language: How Might It Alter the Software Documentation Process and the Role of the Technical Communicator?

    ERIC Educational Resources Information Center

    Battalio, John T.

    2002-01-01

    Describes the influence that Extensible Markup Language (XML) will have on the software documentation process and subsequently on the curricula of advanced undergraduate and master's programs in technical communication. Recommends how curricula of advanced undergraduate and master's programs in technical communication ought to change in order to…

  3. A Five-Year Follow-Up of Students Enrolled in Post-Secondary Vocational-Technical-Transfer Programs.

    ERIC Educational Resources Information Center

    Noeth, Richard J.; Hanson, Gary R.

    The nationwide study examines career behavior patterns and work orientations of students five years after they began vocational-technical transfer programs at community colleges, technical schools, and similar kinds of institutions in the fall of 1970. The study sample consisted of 4,350 individuals selected from the national norm group who…

  4. Where the lay and the technical meet: Using an anthropology of interfaces to explain persistent reproductive health disparities in West Africa.

    PubMed

    Jaffré, Yannick; Suh, Siri

    2016-05-01

    Despite impressive global investment in reproductive health programs in West Africa, maternal mortality remains unacceptably high and obstetric care is often inadequate. Fertility is among the highest in the world, while contraceptive prevalence remains among the lowest. This paper explores the social and technical dimensions of this situation. We argue that effective reproductive health programs require analyzing the interfaces between technical programs and the social logics and behaviors of health professionals and client populations. Significant gaps between health programs' goals and the behaviors of patients and health care professionals have been observed. While public health projects aim to manage reproduction, sexuality, fertility, and professional practices are regulated socially. Such projects may target technical practices, but access to care is greatly influenced by social norms and ethics. This paper shows how an empirical anthropology that investigates the social and technical interfaces of reproduction can contribute to improved global health. Copyright © 2016 Elsevier Ltd. All rights reserved.

  5. Using Corporate-Based Methods To Assess Technical Communication Programs.

    ERIC Educational Resources Information Center

    Faber, Brenton; Bekins, Linn; Karis, Bill

    2002-01-01

    Investigates methods of program assessment used by corporate learning sites and profiles value added methods as a way to both construct and evaluate academic programs in technical communication. Examines and critiques assessment methods from corporate training environments including methods employed by corporate universities and value added…

  6. 76 FR 27648 - World Trade Center (WTC) Health Program Scientific/Technical Advisory Committee; Notice of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-12

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention World Trade... Prevention (CDC), announces the establishment of the World Trade Center (WTC) Health Program Scientific..., Designated Federal Officer, World Trade Center Health Program Scientific/Technical Advisory Committee...

  7. FY 2016 Grant Announcement: FY 2016 Technical Analysis and Programmatic Evaluation Support to the Chesapeake Bay Program Partnership

    EPA Pesticide Factsheets

    The U.S. Environmental Protection Agency’s Chesapeake Bay Program Office is announcing a Request for Proposals for applicants to provide the Chesapeake Bay Program partners with a proposal(s) for providing technical analysis and programmatic evaluation

  8. Lincoln Advanced Science and Engineering Reinforcement (LASER) program

    NASA Technical Reports Server (NTRS)

    Williams, Willie E.

    1989-01-01

    Lincoln University, under the Lincoln Advanced Science and Engineering Reinforcement (LASER) Program, has identified and successfully recruited over 100 students for majors in technical fields. To date, over 70 percent of these students have completed or will complete technical degrees in engineering, physics, chemistry, and computer science. Of those completing the undergraduate degree, over 40 percent have gone on to graduate and professional schools. This success is attributable to well planned approaches to student recruitment, training, personal motivation, retention, and program staff. Very closely coupled to the above factors is a focus designed to achieve excellence in program services and student performance. Future contributions by the LASER Program to the pool of technical minority graduates will have a significant impact. This is already evident from the success of the students that began the first year of the program. With program plans to refine many of the already successful techniques, follow-on activities are expected to make even greater contributions to the availability of technically trained minorities. For example, undergraduate research exposure, broadened summer, and co-op work experiences will be enhanced.

  9. 1981 Bibliography of Technical Writing.

    ERIC Educational Resources Information Center

    Book, Virginia Alm; And Others

    1982-01-01

    Offers resources on technical writing published in 1981. Arranges the citations under the following categories: bibliographies, books, reviews, and articles on the profession; theory and philosophy; pedagogy; technical speech; research; designing degree programs; technical writing and the computer; writing technical articles and reports;…

  10. 45 CFR 1370.3 - Information and technical assistance center grants.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... DEVELOPMENT SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES FAMILY VIOLENCE PREVENTION AND SERVICES PROGRAMS FAMILY VIOLENCE PREVENTION AND SERVICES PROGRAMS § 1370.3 Information and technical assistance center...

  11. Defense Research: Improved Management of DOD’s Technical Corrosion Collaboration Program Needed

    DTIC Science & Technology

    2014-05-01

    Education and Research on Corrosion and Material Performance TCC Technical Corrosion Collaboration UCC University Corrosion Collaboration This is...is the successor to the University Corrosion Collaboration ( UCC ) pilot program, established in 2008. The TCC program builds on efforts of the UCC ...going from a pilot to a full program. They indicated that the UCC pilot program naturally evolved into the TCC pilot program in 2011, and the pilot

  12. Urban Rail Supporting Technology Program Fiscal Year 1974 Year End Summary

    DOT National Transportation Integrated Search

    1975-03-01

    Major areas include program management, technical support and application engineering, facilities development, test and evaluation, and technology development. Specific technical discussion includes track measurement systems; UMTA facilities developm...

  13. The Rebirth of a Career and Technical Education Program.

    ERIC Educational Resources Information Center

    Reese, Susan

    2003-01-01

    Describes how a Milwaukee high school sustained its career and technical education programs by cultivating business-industry partnerships and developing a successful heating, ventilation, air conditioning, and refrigeration curriculum. (JOW)

  14. 40 CFR 52.1690 - Small business technical and environmental compliance assistance program.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... (CONTINUED) New York § 52.1690 Small business technical and environmental compliance assistance program. On January 11, 1993, the New York State Department of Environmental Conservation submitted a plan for the... Assistance Program for incorporation in the New York state implementation plan. This plan meets the...

  15. 40 CFR 52.2732 - Small business technical and environmental compliance assistance program.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... (CONTINUED) Puerto Rico § 52.2732 Small business technical and environmental compliance assistance program. On November 16, 1992, the Puerto Rico Environmental Quality Board submitted a plan for the... Assistance Program for incorporation in the Puerto Rico state implementation plan. This plan meets the...

  16. 40 CFR 52.2732 - Small business technical and environmental compliance assistance program.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... (CONTINUED) Puerto Rico § 52.2732 Small business technical and environmental compliance assistance program. On November 16, 1992, the Puerto Rico Environmental Quality Board submitted a plan for the... Assistance Program for incorporation in the Puerto Rico state implementation plan. This plan meets the...

  17. 40 CFR 52.2732 - Small business technical and environmental compliance assistance program.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... (CONTINUED) Puerto Rico § 52.2732 Small business technical and environmental compliance assistance program. On November 16, 1992, the Puerto Rico Environmental Quality Board submitted a plan for the... Assistance Program for incorporation in the Puerto Rico state implementation plan. This plan meets the...

  18. 77 FR 37060 - Critical Infrastructure and Key Resources (CIKR) Asset Protection Technical Assistance Program...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-20

    ...), National Protection and Programs Directorate (NPPD), Office of Infrastructure Protection (IP.../IP/IICD, 245 Murray Lane SW., Mailstop 0602, Arlington, VA 20598-0602. Email requests should go to... Technical Assistance Program (CAPTAP) is offered jointly by the NPPD/IP and the Federal Emergency Management...

  19. Human Genome: DOE Origins

    Science.gov Websites

    Health and Environmental Research [OHER], the program that supported most Biology in the Department. The origins of DOE's biology program traced to the Manhattan Project, the World War II program that produced Technical Report; 1964 Impact of Radiation Biology on Fundamental Insights in Biology; DOE Technical Report

  20. 77 FR 37390 - Notice Inviting Informal Public Comment on Training and Technical Assistance and Disability...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-21

    ... and Technical Assistance and Disability Inclusion Programming AGENCY: Corporation for National and... Disability Inclusion Programming; correction. SUMMARY: The Corporation for National and Community Service... Disability Inclusion Programming that appeared in the Federal Register of June 11, 2012 (75 FR 34354). That...

  1. 75 FR 30756 - Medicare Program; Supplemental Proposed Changes to the Hospital Inpatient Prospective Payment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-02

    .... 93.773, Medicare--Hospital Insurance; and Program No. 93.774, Medicare-- Supplementary Medical... technical errors that appeared in the supplementary proposed rule entitled ``Medicare Program; Supplemental... Doc. 2010-12567 filed May 21, 2010, there are technical and typographical errors that are identified...

  2. 78 FR 38983 - World Trade Center Health Program Scientific/Technical Advisory Committee (WTCHP-STAC)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-28

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention World Trade Center Health Program Scientific/Technical Advisory Committee (WTCHP-STAC) Correction: This notice was... and Control, (BSC, NCIPC) and the name of the Committee should read World Trade Center Health Program...

  3. CAI Programs and Macros for Formative Curriculum Evaluation.

    ERIC Educational Resources Information Center

    Dasenbrock, David; Teates, Thomas

    This technical memo is designed for persons who are interested in research with and development of curriculum material. Detailed information regarding computer programs, and program documentation used in the development and evaluation of ISCS curriculum materials is provided. The memo includes supplemental information to ISCS Technical Report I…

  4. Science and Engineering Technical Assessments (SETA) Program

    NASA Technical Reports Server (NTRS)

    Huy, Frank

    2000-01-01

    This document provides a project plan for the D.N. American response to Modification #1 to Contract Task Order #13 - Program Maintenance and Logistics for the Science and Engineering Technical Assessments (SETA) contract.

  5. The New Jersey Police Technical Assistance Program

    DOT National Transportation Integrated Search

    2007-03-01

    The Police Technical Assistance Program (PTAP), a federal model, was adopted to support the New Jersey Department of Transportation (NJDOT)s safety mission. Several activities were included in this initiative: conducting assessments, providing tec...

  6. Handbook for Program Developers of Associate of Applied Science and Business Degrees at Lima Technical College.

    ERIC Educational Resources Information Center

    Casto, Robert A.

    Intended as a resource for program developers, this handbook illustrates the process of developing program proposals for the associate of applied science and business (AASB) degrees at Lima Technical College (LTC), in Ohio. Following an introduction, section 1 discusses the potential reasons for the addition of a program to the LTC curriculum.…

  7. Laser Technician Associate Degree Program. A Proposal Submitted to Wisconsin State Board of Vocational, Technical, and Adult Education. (Curriculum Development.) Final Report.

    ERIC Educational Resources Information Center

    North Central Technical Inst., Wausau, WI.

    This final report contains the program proposal with supporting data for developing curriculum materials for and implementing an associate-degree laser technology program at the North Central Technical Institute. The proposal outline provides this information: (1) objectives for the program designed to prepare a technician to safely operate,…

  8. Toward the Development of a Program Quality Framework for Career and Technical Education Programs: A Researcher-Practitioner Collaborative Project

    ERIC Educational Resources Information Center

    Brodersen, R. Marc; Yanoski, David; Hyslop, Alisha; Imperatore, Catherine

    2016-01-01

    Career and technical education (CTE) programs of study are subject to rigorous state and federal accountability systems that provide information on key student outcomes. However, while these outcome measures can form a basis for identifying high- and low-performing programs, they are insufficient for answering underlying questions about how or why…

  9. Evaluation of the Cosmetology Program at Caldwell Community College and Technical Institute--Fall, 1981.

    ERIC Educational Resources Information Center

    Pipes, V. David

    In fall 1981, the cosmetology program at Caldwell Community College and Technical Institute (CCC&TI) was evaluated as part of a process to create a model for the periodic evaluation of all occupational programs at the school. In addition to collecting information for planning and program improvement, the study sought to assess the achievement of…

  10. Evaluation of the Nursing Program at Caldwell Community College and Technical Institute--Summer, 1983.

    ERIC Educational Resources Information Center

    Pipes, V. David

    In summer 1983, an evaluation of the nursing program at Caldwell Community College and Technical Institute was conducted to determine whether program objectives were being met, to measure program success, and to identify areas needing improvement. Surveys were sent to 19 early (pre-1978) and 47 recent Licensed Practical Nurse (LPN) graduates; 17…

  11. Synthesis and Ligand Non-Innocence of Thiolate-Ligated (N4S) Iron(II) and Nickel(II) Bis(imino)pyridine Complexes

    PubMed Central

    Widger, Leland R.; Jiang, Yunbo; Siegler, Maxime; Kumar, Devesh; Latifi, Reza; de Visser, Sam P.; Jameson, Guy N.L.; Goldberg, David P.

    2013-01-01

    The known iron(II) complex [FeII(LN3S)(OTf)] (1) was used as starting material to prepare the new biomimetic (N4S(thiolate)) iron(II) complexes [FeII(LN3S)(py)](OTf) (2) and [FeII(LN3S)(DMAP)](OTf) (3), where LN3S is a tetradentate bis(imino)pyridine (BIP) derivative with a covalently tethered phenylthiolate donor. These complexes were characterized by X-ray crystallography, UV-vis, 1H NMR, and Mössbauer spectroscopy, as well as electrochemistry. A nickel(II) analogue, [NiII(LN3S)](BF4) (5), was also synthesized and characterized by structural and spectroscopic methods. Cyclic voltammetric studies showed 1 – 3 and 5 undergo a single reduction process with E1/2 between −0.9 to −1.2 V versus Fc+/Fc. Treatment of 3 with 0.5% Na/Hg amalgam gave the mono-reduced complex [Fe(LN3S)(DMAP)]0 (4), which was characterized by X-ray crystallography, UV-vis, EPR (g = [2.155, 2.057, 2.038]) and Mössbauer (δ = 0.33 mm s−1; ΔEQ = 2.04 mm s−1) spectroscopies. Computational methods (DFT) were employed to model complexes 3 – 5. The combined experimental and computational studies show that 1 – 3 are 5-coordinate, high-spin (S = 2) FeII complexes, whereas 4 is best described as a 5-coordinate, intermediate-spin (S = 1) FeII complex antiferromagnetically coupled to a ligand radical. This unique electronic configuration leads to an overall doublet spin (Stotal = ½) ground state. Complexes 2 and 3 are shown to react with O2 to give S-oxygenated products, as previously reported for 1. In contrast, the mono-reduced 4 appears to react with O2 to give a mixture of S- and Fe-oxygenates. The nickel(II) complex 5 does not react with O2, and even when the mono-reduced nickel complex is produced, it appears to undergo only outer-sphere oxidation with O2. PMID:23992096

  12. Proceedings of the Annual Meeting of the Council for Programs in Technical and Scientific Communication (14th, Orlando, Florida, October 7-9, 1987).

    ERIC Educational Resources Information Center

    Geonetta, Sam C., Ed.

    Based on the notion of "reaching out," this proceedings presents papers from the annual meeting of the Council for Programs in Technical and Scientific Communication. Papers in the proceedings are: "Southern Tech's Technical Writing Certificate" (William S. Pfeiffer); "Reach Out and Quack Someone" (Daniel R. Jones);…

  13. Identifying Effective Strategies to Providing Technical Support to One-to-One Programs

    ERIC Educational Resources Information Center

    Thomas, Mark W.

    2013-01-01

    The problem of this study was that while one-to-one initiatives in the K-12 environment are growing, the technical support personnel that work in these environments are experiencing problems supporting these initiatives. The purposes of this study were to: (a) identify common problems of providing technical support in a one-to-one laptop program,…

  14. Technical-Oriented Enterprise Resource Planning (ERP) Body of Knowledge for Information Systems Programs: Content and Implementation

    ERIC Educational Resources Information Center

    Boyle, Todd A.

    2007-01-01

    In this article, the author proposes a body of knowledge that the educators can use to incorporate the technical aspects of enterprise resource planning (ERP) into an information systems (IS) program, encapsulated as the ERP technical knowledge framework. To illustrate the application of this framework, the author discusses a course sequence that…

  15. Employers' Perception of Graduates with Entry-Level Technical Skills from Construction Industry Programs in Ghana and Nigeria

    ERIC Educational Resources Information Center

    Acheampong, Philip

    2013-01-01

    The purpose of this comparative study was to identify the technical skills and abilities needed by prospective employees of construction industries in Ghana and Nigeria. Potential employees were defined here as recent graduates of construction industry programs with entry-level technical skills. The continuous growth in and expansion of these two…

  16. The Development of a Project-Based Collaborative Technical Writing Model Founded on Learner Feedback in a Tertiary Aeronautical Engineering Program

    ERIC Educational Resources Information Center

    Tatzl, Dietmar; Hassler, Wolfgang; Messnarz, Bernd; Fluhr, Holger

    2012-01-01

    The present article describes and evaluates collaborative interdisciplinary group projects initiated by content lecturers and an English-as-a-Foreign-Language (EFL) instructor for the purpose of teaching technical writing skills in an aeronautical engineering degree program. The proposed technical writing model is assessed against the results of a…

  17. The Council for Programs in Technical and Scientific Communication Proceedings (6th, Stillwater, Oklahoma, April 26-27, 1979).

    ERIC Educational Resources Information Center

    Warren, Thomas, Ed.

    Articles in these proceedings of a conference of the Council for Programs in Technical and Scientific Communication represent the views of professional communicators and academicians who share a concern for providing breadth and quality of preparation of present and future technical communicators. The 11 articles discuss the following topics: (1)…

  18. A Qualitative Inquiry of Career Exploration in Highly Implemented Career and Technical Education Programs of Study

    ERIC Educational Resources Information Center

    Stipanovic, Natalie; Stringfield, Sam

    2013-01-01

    This qualitative study explores career counseling and guidance services as provided to students engaged in career and technical education programs at three sites in the United States. The sites, consisting of high schools and community colleges, were part of the National Research Center for Career and Technical Education's 5-year studies of…

  19. Proceedings of the Office of Special Education Programs' Annual Technical Assistance and Dissemination Meeting (6th, Washington, DC, January 16-18, 1996).

    ERIC Educational Resources Information Center

    Special Education Programs (ED/OSERS), Washington, DC.

    This document presents the proceedings for the Office of Special Education Programs' 6th Annual Technical Assistance and Dissemination Meeting held on January 16-18, 1996, in Washington, DC. Conference discussions centered around changing expectations for local and state education agencies and technical assistance and dissemination (TA&D)…

  20. Integrated Technical Curriculum. Curriculum Developed for Project Second Chance II: Tech Reading, Tech Science, Tech Math, Automotive.

    ERIC Educational Resources Information Center

    Sorensen, Mary K.; And Others

    This integrated technical curriculum is designed to enroll and retain adult high school noncompleters in occupational programs by providing them with the remedial and content-area reading instruction needed for success in an automotive program. The following topics are covered in the four units: (1) skills for reading technical materials (basics…

  1. Soft Skills in Health Careers Programs: A Case Study of A Regional Vocational Technical High School

    ERIC Educational Resources Information Center

    Park, Chong Myung

    2017-01-01

    The purpose of this study is to develop an understanding of the ways in which educational experiences might differ between a regional vocational technical high school (RVTH) and short-term career-training programs. A particular regional vocational technical high school was selected for its outstanding academic records and placement rates, and a…

  2. The NASA "PERS" Program: Solid Polymer Electrolyte Development for Advanced Lithium-Based Batteries

    NASA Technical Reports Server (NTRS)

    Baldwin, Richard S.; Bennett, William R.

    2007-01-01

    In fiscal year 2000, The National Aeronautics and Space Administration (NASA) and the Air Force Research Laboratory (AFRL) established a collaborative effort to support the development of polymer-based, lithium-based cell chemistries and battery technologies to address the next generation of aerospace applications and mission needs. The ultimate objective of this development program, which was referred to as the Polymer Energy Rechargeable System (PERS), was to establish a world-class technology capability and U.S. leadership in polymer-based battery technology for aerospace applications. Programmatically, the PERS initiative exploited both interagency collaborations to address common technology and engineering issues and the active participation of academia and private industry. The initial program phases focused on R&D activities to address the critical technical issues and challenges at the cell level. Out of a total of 38 proposals received in response to a NASA Research Announcement (NRA) solicitation, 18 proposals (13 contracts and 5 grants) were selected for initial award to address these technical challenges. Brief summaries of technical approaches, results and accomplishments of the PERS Program development efforts are presented. With Agency support provided through FY 2004, the PERS Program efforts were concluded in 2005, as internal reorganizations and funding cuts resulted in shifting programmatic priorities within NASA. Technically, the PERS Program participants explored, to various degrees over the lifetime of the formal program, a variety of conceptual approaches for developing and demonstrating performance of a viable advanced solid polymer electrolyte possessing the desired attributes, as well as several participants addressing all components of an integrated cell configuration. Programmatically, the NASA PERS Program was very successful, even though the very challenging technical goals for achieving a viable solid polymer electrolyte material or the overall envisioned long-term, program objectives were not met due to funding reductions. The NASA PERS Program provided research opportunities and generated and disseminated a wealth of new scientific knowledge and technical competencies within the polymer electrolyte area.

  3. Technical Writing Teachers and the Challenges of Desktop Publishing.

    ERIC Educational Resources Information Center

    Kalmbach, James

    1988-01-01

    Argues that technical writing teachers must understand desktop publishing. Discusses the strengths that technical writing teachers bring to desktop publishing, and the impact desktop publishing will have on technical writing courses and programs. (ARH)

  4. 7 CFR 652.5 - Participant acquisition of technical services.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... technical service providers. (d) The Department may approve written agreements for technical assistance... identify in the particular program contract or written agreement the payment provisions for technical... 7 Agriculture 6 2010-01-01 2010-01-01 false Participant acquisition of technical services. 652.5...

  5. Range Flight Safety Requirements

    NASA Technical Reports Server (NTRS)

    Loftin, Charles E.; Hudson, Sandra M.

    2018-01-01

    The purpose of this NASA Technical Standard is to provide the technical requirements for the NPR 8715.5, Range Flight Safety Program, in regards to protection of the public, the NASA workforce, and property as it pertains to risk analysis, Flight Safety Systems (FSS), and range flight operations. This standard is approved for use by NASA Headquarters and NASA Centers, including Component Facilities and Technical and Service Support Centers, and may be cited in contract, program, and other Agency documents as a technical requirement. This standard may also apply to the Jet Propulsion Laboratory or to other contractors, grant recipients, or parties to agreements to the extent specified or referenced in their contracts, grants, or agreements, when these organizations conduct or participate in missions that involve range flight operations as defined by NPR 8715.5.1.2.2 In this standard, all mandatory actions (i.e., requirements) are denoted by statements containing the term “shall.”1.3 TailoringTailoring of this standard for application to a specific program or project shall be formally documented as part of program or project requirements and approved by the responsible Technical Authority in accordance with NPR 8715.3, NASA General Safety Program Requirements.

  6. The Challenges of Career and Technical Education Concurrent Enrollment: An Administrative Perspective

    ERIC Educational Resources Information Center

    Haag, Patricia W.

    2015-01-01

    Career and technical education concurrent enrollment may pose unique challenges in programming and enrollment for program administrators, and this chapter describes the experiences and challenges of a CTE concurrent enrollment administrator.

  7. Technical assistance from state health departments for communities engaged in policy, systems, and environmental change: the ACHIEVE Program.

    PubMed

    Hefelfinger, Jenny; Patty, Alice; Ussery, Ann; Young, Walter

    2013-10-24

    This study assessed the value of technical assistance provided by state health department expert advisors and by the staff of the National Association of Chronic Disease Directors (NACDD) to community groups that participated in the Action Communities for Health, Innovation, and Environmental Change (ACHIEVE) Program, a CDC-funded health promotion program. We analyzed quantitative and qualitative data reported by community project coordinators to assess the nature and value of technical assistance provided by expert advisors and NACDD staff and the usefulness of ACHIEVE resources in the development and implementation of community action plans. A grounded theory approach was used to analyze and categorize phrases in text data provided by community coordinators. Open coding placed conceptual labels on text phrases. Frequency distributions of the quantitative data are described and discussed. The most valuable technical assistance and program support resources were those determined to be in the interpersonal domain (ie, interactions with state expert advisors, NACDD staff, and peer-to-peer support). The most valuable technical assistance events were action institutes, coaches' meetings, webinars, and technical assistance conference calls. This analysis suggests that ACHIEVE communities valued the management and training assistance provided by expert advisors and NACDD staff. State health department expert advisors provided technical guidance and support, including such skills or knowledge-based services as best-practice strategies, review and discussion of community assessment data, sustainability planning, and identification of possible funding opportunities. NACDD staff led development and implementation of technical assistance events.

  8. Training and technical assistance to enhance capacity building between prevention research centers and their partners.

    PubMed

    Spadaro, Antonia J; Grunbaum, Jo Anne; Dawkins, Nicola U; Wright, Demia S; Rubel, Stephanie K; Green, Diane C; Simoes, Eduardo J

    2011-05-01

    The Centers for Disease Control and Prevention has administered the Prevention Research Centers Program since 1986. We quantified the number and reach of training programs across all centers, determined whether the centers' outcomes varied by characteristics of the academic institution, and explored potential benefits of training and technical assistance for academic researchers and community partners. We characterized how these activities enhanced capacity building within Prevention Research Centers and the community. The program office collected quantitative information on training across all 33 centers via its Internet-based system from April through December 2007. Qualitative data were collected from April through May 2007. We selected 9 centers each for 2 separate, semistructured, telephone interviews, 1 on training and 1 on technical assistance. Across 24 centers, 4,777 people were trained in 99 training programs in fiscal year 2007 (October 1, 2006-September 30, 2007). Nearly 30% of people trained were community members or agency representatives. Training and technical assistance activities provided opportunities to enhance community partners' capacity in areas such as conducting needs assessments and writing grants and to improve the centers' capacity for cultural competency. Both qualitative and quantitative data demonstrated that training and technical assistance activities can foster capacity building and provide a reciprocal venue to support researchers' and the community's research interests. Future evaluation could assess community and public health partners' perception of centers' training programs and technical assistance.

  9. Basic Skills Assessment Program. Technical Report.

    ERIC Educational Resources Information Center

    Los Angeles County Superintendent of Schools, CA.

    This is the second technical report on the Basic Skills Assessment Program for the Department of Defense Dependents Schools (DoDDS). The report includes a summary of 1979-80 testing activities organized into five chapters. The first chapter provides an overview of report contents and a brief history of the testing program. The second chapter…

  10. Mature Programs of Study: Examining Policy Implementation at the Local Level. Final Report

    ERIC Educational Resources Information Center

    Alfeld, Corinne; Bhattacharya, Sharika

    2013-01-01

    The 2006 Carl D. Perkins Career and Technical Education Act required that all career technical education (CTE) programs offer secondary to postsecondary programs of study (POS), which integrate rigorous academics, offer dual enrollment options, and lead to an industry-recognized degree or credential. Focused on improving students' transition to…

  11. Cobra Strikes! High-Performance Car Inspires Students, Markets Program

    ERIC Educational Resources Information Center

    Jenkins, Bonita

    2008-01-01

    Nestled in the Lower Piedmont region of upstate South Carolina, Piedmont Technical College (PTC) is one of 16 technical colleges in the state. Automotive technology is one of its most popular programs. The program features an instructive, motivating activity that the author describes in this article: building a high-performance car. The Cobra…

  12. 48 CFR 227.7104 - Contracts under the Small Business Innovation Research (SBIR) Program.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Data and Computer Software—Small Business Innovation Research (SBIR) Program, when technical data or computer software will be generated during performance of contracts under the SBIR program. (b) Under the clause at 252.227-7018, the Government obtains SBIR data rights in technical data and computer software...

  13. 48 CFR 227.7104 - Contracts under the Small Business Innovation Research (SBIR) Program.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Data and Computer Software—Small Business Innovation Research (SBIR) Program, when technical data or computer software will be generated during performance of contracts under the SBIR program. (b) Under the clause at 252.227-7018, the Government obtains SBIR data rights in technical data and computer software...

  14. Feasibility study of an Integrated Program for Aerospace vehicle Design (IPAD). Volume 5: Catalog of IPAD technical program elements

    NASA Technical Reports Server (NTRS)

    Gillette, W. B. (Editor); Southall, J. W. (Editor)

    1973-01-01

    The catalog is presented of technical program elements which are required to support the design activities for a subsonic and supersonic commercial transport. Information for each element consists of usage and storage information, ownership, status and an abstract describing the purpose of the element.

  15. Building Interest in Math and Science for Rural and Underserved Elementary School Children Using Robots

    ERIC Educational Resources Information Center

    Matson, Eric; DeLoach, Scott; Pauly, Robyn

    2004-01-01

    The "Robot Roadshow Program" is designed to increase the interest of elementary school children in technical disciplines, specifically math and science. The program focuses on children from schools categorized as rural or underserved, which often have limited access to advanced technical resources. We developed the program using robots…

  16. Supporting Minority-Serving Institutions in Their Program Improvement Efforts: A Responsive Technical Assistance Approach

    ERIC Educational Resources Information Center

    Bay, Mary; Lopez-Reyna, Norma A.; Guillory, Barbara L.

    2012-01-01

    To reform a special education teacher preparation program can be gratifying, difficult, complex, political, and urgently needed. The Monarch Center, a federally funded technical assistance center, was established to guide and support minority-serving institutions in their efforts to improve their teacher preparation programs. Four guidelines…

  17. Kentucky Career and Technical Teacher Education Programs/Ongoing Issues

    ERIC Educational Resources Information Center

    Workman, Ed; Stubbs, Joyce

    2012-01-01

    What is Career and Technical Education (CTE)? How does one identify and recognized strong CTE educational programs? And after one has answers to the first two questions, how does one successfully align CTE teacher education (CTTE) programs across large institutions such as colleges within universities, or in Kentucky's endeavor within universities…

  18. 75 FR 70013 - Medicare Program; Inpatient Rehabilitation Facility Prospective Payment System for Federal Fiscal...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-16

    ... Insurance; and Program No. 93.774, Medicare-- Supplementary Medical Insurance Program) Dated: November 9...: Correction notice. SUMMARY: This document corrects a technical error that appeared in the notice published in... of July 22, 2010 (75 FR 42836), there was a technical error that we are identifying and correcting in...

  19. A Review of Technical Communication Programs Outside the United States.

    ERIC Educational Resources Information Center

    Alred, Gerald J.

    2001-01-01

    Examines technical communication programs outside the United States and comments on such features as their location in the university structure, links with public relations, the inclusion of internships or practicums, the balance of theory and practice, and typical course offerings. Lists a dozen major programs in seven countries. Concludes that…

  20. How to Recognize a Quality Technical Education Program.

    ERIC Educational Resources Information Center

    Doty, Charles R.

    Criteria for the evaluation of quality technical educational programs must be identified if follow-up studies are to be effective. Current research shows that problems in the development of such criteria include the tendency to evaluate programs on the basis of organizational structure rather than on the quality of the instructional program…

  1. Outcomes of an Independent Review and Guidelines for the Implementation of a Program Review Model. Volume II. Technical Report.

    ERIC Educational Resources Information Center

    Carvell Education Managment Planning, Inc., Los Angeles, CA.

    The second part of a report on a comprehensive review of the credit instructional programs offered by Pasadena City College (PCC), this volume contains a technical description of the data collection and assembly procedures used in the program review and provides guidelines for the implementation of the program review model. The first section…

  2. Measures of Success: A Survey of Selected Vocational and Technical Education Programs in Florida which Train Students in Occupations Requiring Licenses.

    ERIC Educational Resources Information Center

    Florida State Advisory Council on Vocational and Technical Education, Tallahassee.

    A study of 13 vocational and technical education programs in Florida was conducted which represented an attempt to identify valid and reliable sources of data whereby some vocational programs might be evaluated in specified terms of effectiveness. The programs selected for study were among those which require graduating students to pass licensing…

  3. Proceedings of the Annual Meeting of the Council for Programs in Technical and Scientific Communication (24th, Austin, Texas, October 16-18, 1997).

    ERIC Educational Resources Information Center

    Council for Programs in Technical and Scientific Communication.

    Based on the theme of connections in technical and scientific communication, this proceedings presents 47 papers delivered at the 1997 annual meeting of the Council for Programs in Technical and Scientific Communication (CPTSC). Papers in the proceedings are divided into 10 sections: (1) Theoretical Connections; (2) Legal and Ethical Connections;…

  4. Economic Returns to Sub-Baccalaureate Technical Education: A Study of Labor Market Outcomes for Manufacturing Engineering Technologist and Technician Education (METTE) Programs in the Wisconsin Technical College System

    ERIC Educational Resources Information Center

    Matheny, Christopher J.

    2013-01-01

    The purpose of this study is to examine the labor market outcomes of sub-baccalaureate education for individuals attending Manufacturing Engineering Technologist and Technician Education (METTE) programs in the Wisconsin Technical College System. Increasingly, public policy for postsecondary education and economic development, as well as decisions…

  5. Meeting the Needs of Career and Technical Education: Observations from Graduates of a High School Health Science Program

    ERIC Educational Resources Information Center

    Avey, Matthew R.

    2012-01-01

    Career and Technical education has been around for some time, and has often been shaped by the current economic landscape of the country. While current evolving trends focus on relevance for students in the school setting, a coexistence with college preparation curriculum is now the new trend in modern technical education. New programs have…

  6. OSH technical reference manual

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1993-11-01

    In an evaluation of the Department of Energy (DOE) Occupational Safety and Health programs for government-owned contractor-operated (GOCO) activities, the Department of Labor`s Occupational Safety and Health Administration (OSHA) recommended a technical information exchange program. The intent was to share written safety and health programs, plans, training manuals, and materials within the entire DOE community. The OSH Technical Reference (OTR) helps support the secretary`s response to the OSHA finding by providing a one-stop resource and referral for technical information that relates to safe operations and practice. It also serves as a technical information exchange tool to reference DOE-wide materials pertinentmore » to specific safety topics and, with some modification, as a training aid. The OTR bridges the gap between general safety documents and very specific requirements documents. It is tailored to the DOE community and incorporates DOE field experience.« less

  7. Director's discretionary fund

    NASA Technical Reports Server (NTRS)

    1993-01-01

    This technical memorandum contains brief technical papers describing research and technology development programs sponsored by the ARC Director's Discretionary Fund during fiscal year 1992 (Oct. 1991 through Sep. 1992). An appendix provides administrative information for each of the 45 sponsored research programs.

  8. Pennsylvania Department of Transportation's Local Technical Assistance Program (LTAP).

    DOT National Transportation Integrated Search

    2010-11-01

    The Pennsylvania Department of Transportations (PennDOT) Local Technical Assistance Program : (LTAP) was awarded to the Pennsylvania State Association of Township Supervisors (PSATS), with the : contract start date of December 1, 2005. PSATS led t...

  9. DOE Office of Scientific and Technical Information (OSTI.GOV)

    This fact provides information on the Strategic Technical Assistance Response Team (START) Program, a U.S. Department of Energy Office of Indian Energy Policy and Programs (DOE-IE) initiative to provide technical expertise to support the development of next-generation energy projects in Indian Country.

  10. Technical basis for external dosimetry at the Waste Isolation Pilot Plant (WIPP)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bradley, E.W.; Wu, C.F.; Goff, T.E.

    1993-12-31

    The WIPP External Dosimetry Program, administered by Westinghouse Electric Corporation, Waste Isolation Division, for the US Department of Energy (DOE), provides external dosimetry support services for operations at the Waste Isolation Pilot Plant (WIPP) Site. These operations include the receipt, experimentation with, storage, and disposal of transuranic (TRU) wastes. This document describes the technical basis for the WIPP External Radiation Dosimetry Program. The purposes of this document are to: (1) provide assurance that the WIPP External Radiation Dosimetry Program is in compliance with all regulatory requirements, (2) provide assurance that the WIPP External Radiation Dosimetry Program is derived from amore » sound technical base, (3) serve as a technical reference for radiation protection personnel, and (4) aid in identifying and planning for future needs. The external radiation exposure fields are those that are documented in the WIPP Final Safety Analysis Report.« less

  11. A review and evaluation of the Langley Research Center's Scientific and Technical Information Program: Results of phase 6: The technical report. A survey and analysis

    NASA Technical Reports Server (NTRS)

    Mccullough, R. A.; Pinelli, T. E.; Pilley, D. D.; Stohrer, F. F.

    1982-01-01

    Current practice and usage using selected technical reports; literature relative to the sequential, language, and presentation components of technical reports; and NASA technical report publications standards are discussed. The effctiveness of the technical report as a product for information dissemination is considered.

  12. 12 CFR 705.10 - Technical assistance.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 6 2010-01-01 2010-01-01 false Technical assistance. 705.10 Section 705.10... DEVELOPMENT REVOLVING LOAN PROGRAM FOR CREDIT UNIONS § 705.10 Technical assistance. NCUA may provide technical... or NCUA. NCUA will base technical assistance on funds availability, the needs of the participating...

  13. 48 CFR 825.870 - Technical assistance.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Technical assistance. 825... SOCIOECONOMIC PROGRAMS FOREIGN ACQUISITION Other International Agreements and Coordination 825.870 Technical assistance. Contracting officers may obtain technical information or guidance on international agreements and...

  14. Transportable educational programs for scientific and technical professionals: More effective utilization of automated scientific and technical data base systems

    NASA Technical Reports Server (NTRS)

    Dominick, Wayne D.

    1987-01-01

    This grant final report executive summary documents a major, long-term program addressing innovative educational issues associated with the development, administration, evaluation, and widespread distribution of transportable educational programs for scientists and engineers to increase their knowledge of, and facilitate their utilization of automated scientific and technical information storage and retrieval systems. This educational program is of very broad scope, being targeted at Colleges of Engineering and Colleges of Physical sciences at a large number of colleges and universities throughout the United States. The educational program is designed to incorporate extensive hands-on, interactive usage of the NASA RECON system and is supported by a number of microcomputer-based software systems to facilitate the delivery and usage of the educational course materials developed as part of the program.

  15. Support Equipment Management in the F/A-18 Program

    DTIC Science & Technology

    1986-12-01

    or character (such as manuals and drawings) of a scientific or technical nature. Computer programs and related software are not technical data...documentation of computer programs and related software are. Also excluded are financial data or other information related to contract administration. 6...management in the F/A-18 program . Graeser, Kenneth S. http://hdl.handle.net/10945/22133 Downloaded from NPS Archive: Calhoun NAVAL POSTGRADUATE SCHOOL Monterey

  16. Inventory of Academic Programs. Volume Three. Public Junior and Community Colleges, Regional Technical Institute. A Planning Document of the Alabama Commission on Higher Education.

    ERIC Educational Resources Information Center

    Alabama State Commission on Higher Education, Montgomery.

    An inventory of academic programs offered for credit and learning to an academic award offered by Alabama's public junior and community colleges and by the Regional Technical Institute as of June 1, 1985, is presented. For each college and program, charts indicate program titles, levels of degrees offered, and accreditation status. Included are…

  17. Contributing to Tourism Industry Vitality of a Natural Resource Based Region through Educational/Technical Assistance. Staff Paper Series P83-20.

    ERIC Educational Resources Information Center

    Blank, Uel; And Others

    From 1979 to 1982 an extension education program provided assistance to the tourism industry in rural communities adjoining northeastern Minnesota's Boundary Waters Canoe Area (BWCA). Program activities involved needs assessment, educational and technical assistance to communities and tourism-related firms, marketing programs, grants management…

  18. Accounting Technology Associate Degree. Louisiana Technical Education Program and Course Standards. Competency-Based Postsecondary Curriculum Outline from Bulletin 1822.

    ERIC Educational Resources Information Center

    Louisiana State Dept. of Education, Baton Rouge. Div. of Vocational Education.

    This document outlines the curriculum of Louisiana's accounting technology associate degree program, which is a 6-term (77-credit hour) competency-based program designed to prepare students for employment as accounting technicians providing technical administrative support to professional accountants and other financial management personnel.…

  19. Fifty Indices of Effectiveness Regarding the Program Advisory Committees in Minnesota's Technical Colleges: A Working Paper. Effective Advisory Committees Project.

    ERIC Educational Resources Information Center

    Mercer, John W.; Meunier, Greg R.

    This document, which was developed by a task force whose members represent the instructional, student support service, administrative, and executive ranks of technical colleges with very diverse sizes, locations, and programs, lists 50 proposed indices of effectiveness regarding the program advisory committees (ACs) in Minnesota's technical…

  20. A Descriptive Study of the Classroom Instruction Component of the ESEA Title VII Bilingual Education Program. Technical Report.

    ERIC Educational Resources Information Center

    Cardenas, Rene F.; And Others

    The technical report portion of a national survey of bilingual education programs funded under Title VII of the Elementary and Secondary Education Act is presented. The study, conducted during 1979-83, describes the characteristics of the programs' classroom instruction component. Basic project directors and parent advisory committee chairpersons…

  1. The Rock Valley College Career Advancement Program.

    ERIC Educational Resources Information Center

    Rock Valley Coll., Rockford, IL.

    The Career Advancement Program (CAP) is a joint effort by a 2-year college and industrial firms in its district to expand educational opportunities, to match college programs to local needs, and to help industry meet its present and future technical manpower needs. CAP has worked to attract students, full- or part-time, to technical training.…

  2. Non-Technical Medical Care: An In-Home Care Program.

    ERIC Educational Resources Information Center

    Oklahoma State Dept. of Human Services, Oklahoma City.

    This document describes the Non-Technical Medical Care (NTMC) program, a personal care service offered by the Oklahoma Department of Human Services to eligible persons in their own homes. These NTMC program goals are listed: to provide personal care services to frail elderly and disabled persons, allowing them to remain in their homes; and to…

  3. Annual Technical Progress Report for Emergency School Assistance Program, Title 45, 1970-71.

    ERIC Educational Resources Information Center

    Lindsey, Randall B.

    This paper presents a technical progress report of two programs conducted with funds provided under the Emergency School Assistance Program. One, the Mobile Learning Unit, said to have been designed to measure changes in fourth and fifth grade students' self-concept in a reorganized desegregated school environment, focuses on whether a positive…

  4. State Department Early Childhood Education Program Specialists' Review of the Content and Technical Quality of AEL's "Around the Bend" Pilot Tapes. Technical Report No. 30.

    ERIC Educational Resources Information Center

    Shively, Joe E.

    In order to determine whether Appalachia Educational Laboratory (AEL) had the capacity to produce a TV series of technical quality and whose content meets criteria designed for the selection of children's television programs, two pilot tapes were produced by AEL and submitted for rating to seven early childhood education specialists from seven…

  5. Rapid Development: A Content Analysis Comparison of Literature and Purposive Sampling of AFRL Rapid Reaction Projects

    DTIC Science & Technology

    2011-12-01

    systems engineering technical and technical management processes. Technical Planning, Stakeholders Requirements Development, and Architecture Design were...Stakeholder Requirements Definition, Architecture Design and Technical Planning. A purposive sampling of AFRL rapid development program managers and engineers...emphasize one process over another however Architecture Design , Implementation scored higher among Technical Processes. Decision Analysis, Technical

  6. Technical Assistance From State Health Departments for Communities Engaged in Policy, Systems, and Environmental Change: The ACHIEVE Program

    PubMed Central

    Hefelfinger, Jenny; Patty, Alice; Ussery, Ann

    2013-01-01

    Introduction This study assessed the value of technical assistance provided by state health department expert advisors and by the staff of the National Association of Chronic Disease Directors (NACDD) to community groups that participated in the Action Communities for Health, Innovation, and Environmental Change (ACHIEVE) Program, a CDC-funded health promotion program. Methods We analyzed quantitative and qualitative data reported by community project coordinators to assess the nature and value of technical assistance provided by expert advisors and NACDD staff and the usefulness of ACHIEVE resources in the development and implementation of community action plans. A grounded theory approach was used to analyze and categorize phrases in text data provided by community coordinators. Open coding placed conceptual labels on text phrases. Frequency distributions of the quantitative data are described and discussed. Results The most valuable technical assistance and program support resources were those determined to be in the interpersonal domain (ie, interactions with state expert advisors, NACDD staff, and peer-to-peer support). The most valuable technical assistance events were action institutes, coaches’ meetings, webinars, and technical assistance conference calls. Conclusion This analysis suggests that ACHIEVE communities valued the management and training assistance provided by expert advisors and NACDD staff. State health department expert advisors provided technical guidance and support, including such skills or knowledge-based services as best-practice strategies, review and discussion of community assessment data, sustainability planning, and identification of possible funding opportunities. NACDD staff led development and implementation of technical assistance events. PMID:24157078

  7. The Successful Teacher in Technical Education: The Preparation of the Successful Teacher.

    ERIC Educational Resources Information Center

    Storm, George

    The purposes of this study were to identify success factors in technical education teaching and to obtain subject matter recommendations for the improvement of technical teacher education. A national population of technical education directors offering post-secondary technical education programs in 1963 under Title III of the National Defense…

  8. Technical writing versus technical writing

    NASA Technical Reports Server (NTRS)

    Dillingham, J. W.

    1981-01-01

    Two terms, two job categories, 'technical writer' and 'technical author' are discussed in terms of industrial and business requirements and standards. A distinction between 'technical writing' and technical 'writing' is made. The term 'technical editor' is also considered. Problems inherent in the design of programs to prepare and train students for these jobs are discussed. A closer alliance between industry and academia is suggested as a means of preparing students with competent technical communication skills (especially writing and editing skills) and good technical skills.

  9. Sometimes, It Takes a Village

    ERIC Educational Resources Information Center

    Taylor, Gwen; Heflin, David

    2015-01-01

    In this article, Gwen Taylor describes the West Kentucky Community and Technical College (WKCTC) groundbreaking program, "Accelerating Opportunity" (AO), which targeted students who are deficient in math, reading, or writing. The program uses the Washington State Board for Community & Technical Colleges' (2013) Integrated Basic…

  10. 78 FR 2449 - Office of Small Credit Unions (OSCUI) Grant Program Access for Credit Unions

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-11

    ... availability. The OSCUI Grant Program serves as a source of financial support, in the form of technical... provides financial support in the form of technical assistance grants to LICUs. These funds help improve...

  11. 15 CFR 256.2 - The Research Associate Program.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... competence, and technical supervision for defined scientific or technical research by a Research Associate when such research is complementary to and compatible with scientific or technical research being... salaries of their Research Associates and Sponsor-furnished technical assistants and secretaries of the...

  12. Science, Technology, and Communication: Program Design in the Past, Present, and Future. Proceedings of the Annual Meeting of the Council for Programs in Technical and Scientific Communication (26th, Santa Fe, New Mexico, October 14-16, 1999).

    ERIC Educational Resources Information Center

    Rude, Carolyn, Ed.

    Based on the theme of the past, present, and future of science, technology, and communication programs, this proceedings presents 49 papers delivered at the 1999 annual meeting of the Council for Programs in Technical and Scientific Communication (CPTSC). Papers in the proceedings are divided into 12 subsections: The Shape of Programs: Past,…

  13. State “Technical Assistance Programs” for nursing home quality improvement: variations and potential implications

    PubMed Central

    Li, Yue; Spector, Williams D.; Glance, Laurent G.; Mukamel, Dana B.

    2013-01-01

    Context To improve nursing home quality, many states developed “Technical Assistance Programs” that provide on-site consultation and training for nursing facility staff. Methods We conducted a national survey on these state programs to collect data on program design, operations, financing, and perceived effectiveness. Results As of 2010, 17 states have developed such programs. Compared to existing state nursing home quality regulations, these programs represent a collaborative, rather than enforcement-oriented, approach to quality. However, existing programs vary substantially in key structural features such as staffing patterns, funding levels, and relationship with state survey and certification agencies. Perceived effectiveness by program officials on quality was high, although few states have performed formal evaluations. Perceived barriers to program effectiveness included lack of appropriate staff and funding, among others. Conclusion State “Technical Assistance Programs” for nursing homes varies in program design and perceived effectiveness. Future comparative evaluations are needed to inform evidence-based quality initiatives. PMID:23216345

  14. Report of the Defense Science Board Task Force on National Aero-Space Plane (NASP) Program

    NASA Technical Reports Server (NTRS)

    1992-01-01

    Six years ago, the Defense Science Board (DSB) initiated a review of the concept, technical basis, program content, and missions of the National Aerospace Plane (NASP) program. The report was completed in Sep. 1988, and the recommendations contributed to strengthening the technical efforts in the NASP program. Since then, substantial technological progress has been made in the technology development phase (Phase 2) of the program. Phase 2 of the program is currently scheduled to end in late Fiscal Year 1993, with a decision whether to proceed to the experimental flight vehicle phase (Phase 3) to be made at that time. This decision will be a very significant one for the Department of Defense (DoD) and the National Aeronautics and Space Administration (NASA). In February of this year, the DSB was chartered to revisit the NASP program to assess the degree to which the many technical challenges of the program have been resolved, or are likely to be resolved by the end of Phase 2.

  15. Idaho National Laboratory Annual Report FY 2013 LDRD Project Summaries

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Dena Tomchak

    The FY 2013 LDRD Annual Report is a compendium of the diverse research performed to develop and ensure the INL’s technical capabilities support the current and future DOE missions and national research priorities. LDRD is essential to INL—it provides a means for the Laboratory to maintain scientific and technical vitality while funding highly innovative, high-risk science and technology research and development (R&D) projects. The program enhances technical capabilities at the Laboratory, providing scientific and engineering staff with opportunities to explore proof-of-principle ideas, advanced studies of innovative concepts, and preliminary technical analyses. Established by Congress in 1991, the LDRD Program provesmore » its benefit each year through new programs, intellectual property, patents, copyrights, national and international awards, and publications.« less

  16. The NASA Scientific and Technical Information (STI) Program's Implementation of Open Archives Initiation (OAI) for Data Interoperability and Data Exchange

    NASA Technical Reports Server (NTRS)

    Rocker, JoAnne; Roncaglia, George J.; Heimerl, Lynn N.; Nelson, Michael L.

    2002-01-01

    Interoperability and data-exchange are critical for the survival of government information management programs. E-government initiatives are transforming the way the government interacts with the public. More information is to be made available through web-enabled technologies. Programs such as the NASA's Scientific and Technical Information (STI) Program Office are tasked to find more effective ways to disseminate information to the public. The NASA STI Program is an agency-wide program charged with gathering, organizing, storing, and disseminating NASA-produced information for research and public use. The program is investigating the use of a new protocol called the Open Archives Initiative (OAI) as a means to improve data interoperability and data collection. OAI promotes the use of the OAI harvesting protocol as a simple way for data sharing among repositories. In two separate initiatives, the STI Program is implementing OAI In collaboration with the Air Force, Department of Energy, and Old Dominion University, the NASA STI Program has funded research on implementing the OAI to exchange data between the three organizations. The second initiative is the deployment of OAI for the NASA technical report server (TRS) environment. The NASA TRS environment is comprised of distributed technical report servers with a centralized search interface. This paper focuses on the implementation of OAI to promote interoperability among diverse data repositories.

  17. The NASA Scientific and Technical Information Program: Exploring challenges, creating opportunities

    NASA Technical Reports Server (NTRS)

    Sepic, Ronald P.

    1993-01-01

    The NASA Scientific and Technical Information (STI) Program offers researchers access to the world's largest collection of aerospace information. An overview of Program activities, products and services, and new directions is presented. The R&D information cycle is outlined and specific examples of the NASA STI Program in practice are given. Domestic and international operations and technology transfer activities are reviewed and an agenda for the STI Program NASA-wide is presented. Finally, the incorporation of Total Quality Management and evaluation metrics into the STI Program is discussed.

  18. An Effective Health and Medical Technical Authority

    NASA Technical Reports Server (NTRS)

    Fogarty, Jennifer A.

    2009-01-01

    The NASA Governance model directed the formation of three Technical Authorities, Engineering; Safety and Mission Assurance; and Health and Medical, to ensure that risks are identified and adjudicated efficiently and transparently in concert with the spaceflight programs and projects. The Health and Medical Technical Authority (HMTA) has been implemented at the Johnson Space Center (JSC) and consists of the Chief Medical Office (CMO), the Deputy CMO, and HMTA Delegates. The JSC HMTA achieves the goals of risk identification and adjudication through the discharge of the appropriate technical expertise to human space flight programs and projects and the escalation of issues within program and technical authority boards. The JSC HMTA relies on subject matter experts (SMEs) in the Space Life Sciences Directorate at JSC as well as experts from other Centers to work crew health and performance issues at the technical level, develop requirements, oversee implementation and validation of requirements, and identify risks and non-compliances. Once a risk or potential noncompliance has been identified and reported to the programs or projects, the JSC HMTA begins to track it and closely monitor the program's or project's response. As a risk is developed or a non-compliance negotiated, positions from various levels of decision makers are sought at the program and project control boards. The HMTA may support a program or project position if it is satisfied with the decision making and vetting processes (ex. the subject matter expert voiced his/her concerns and all dissenting opinions were documented) and finds that the position both acknowledges the risk and cost of the mitigation and resolves the issue without changing NASA risk posture. The HMTA may disagree with a program or project position if the NASA risk posture has been elevated or obfuscated. If the HMTA does disagree with the program or project position, it will appeal to successively higher levels of authority so that risk acceptance and risk trades will be acknowledged and sanctioned at the highest appropriate level; this includes Program Managers, Mission Directorate Associate Administrators and the Agency Administrator.

  19. Selected Technical Spin Offs from the Space Program

    NASA Technical Reports Server (NTRS)

    Gilmore, H. L.

    1970-01-01

    The report describes some of the problems which the National Aeronautics and Space Administration has encountered in getting people to understand how the general public has profited from the technical discoveries of the space program. Next, it describes NASA's Technology Utilization Program and comments on it. It then describes some of the many spin-offs from the space program. These include examples from management technology, communications, aeronautics, medicine, fabrics highway safety, and weather forecasting.

  20. Configuration management program plan for Hanford site systems engineering

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kellie, C.L.

    This plan establishes the integrated management program for the evolving technical baseline developed through the systems engineering process. This configuration management program aligns with the criteria identified in the DOE Standard, DOE-STD-1073-93. Included are specific requirements for control of the systems engineering RDD-100 database, and electronic data incorporated in the database that establishes the Hanford Site Technical Baseline.

  1. The Treatment of Assets and Income From Assets in Income-Conditioned Government Benefit Programs; Technical Papers.

    ERIC Educational Resources Information Center

    Wisconsin Univ., Madison. Inst. for Research on Poverty.

    These technical papers were presented at the Conference on Treatment of Assets and Income from Assets in Income Conditioned Programs. Six papers dealing with current and alternative treatments of assets and income from assets in programs that offer both cash and noncash benefits were presented. The first three authors reviewed the network of rules…

  2. The NASA Scientific and Technical Information (STI) Program's Implementation of Open Archives Initiative (OAI) for Data Interoperability and Data Exchange.

    ERIC Educational Resources Information Center

    Rocker, JoAnne; Roncaglia, George J.; Heimerl, Lynn N.; Nelson, Michael L.

    Interoperability and data-exchange are critical for the survival of government information management programs. E-government initiatives are transforming the way the government interacts with the public. More information is to be made available through Web-enabled technologies. Programs such as the NASA's Scientific and Technical Information (STI)…

  3. The PRO-TECH Program. A Program for Gifted and Talented High School Students in Connecticut's Vocational-Technical School System.

    ERIC Educational Resources Information Center

    Brann, Ronald E.

    This document describes Connecticut's PRO-TECH Program, which is designed to link pupils in vocational-technical schools, resources of school and community, and opportunity for growth in order to teach advanced skills, explore new interests, challenge old ideas, and highlight individual talents. The document consists of sections on the following…

  4. Wilder-Naifeh Technical Skills Grant Program Report: A Baseline Evaluation

    ERIC Educational Resources Information Center

    Tennessee Higher Education Commission, 2010

    2010-01-01

    The Wilder-Naifeh Technical Skills Grant, introduced in Winter 2004, grants awards of up to $2,000 to students who attend one of the 27 Tennessee Technology Centers. Since the inception of this program, approximately 50,000 students have received grants, and the state of Tennessee has spent roughly $47.5 million on the program over the last four…

  5. 10 CFR 455.134 - Forwarding of applications for State grants for technical assistance, program assistance, and...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 3 2010-01-01 2010-01-01 false Forwarding of applications for State grants for technical assistance, program assistance, and marketing. 455.134 Section 455.134 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION GRANT PROGRAMS FOR SCHOOLS AND HOSPITALS AND BUILDINGS OWNED BY UNITS OF LOCAL GOVERNMENT AND PUBLIC CARE INSTITUTIONS State...

  6. Agricultural Programs at the Post High School Level; Special Report Prepared for the Pacific Regional Seminar in Agricultural Education (Olympia, May 15-19, 1967).

    ERIC Educational Resources Information Center

    Hensel, James W.

    A general overview of post-high school education in agriculture is presented to show the wide variety of programs and their curricular structure for use by school administrators. Representative agricultural programs in community colleges, junior colleges, vocational and technical schools, area schools, and in specialized technical training…

  7. The Impact of Career and Technical Education Programs on At-Risk Secondary Students

    ERIC Educational Resources Information Center

    Smith, Sabrina E.

    2012-01-01

    As the number of youth at risk for educational failure has increased, so has the debate over the appropriate nature of career and technical education (CTE) programs for such youth. The purpose of this study was to gain an understanding about the manner in which CTE programs within vocational schools affected secondary students at risk for…

  8. An Evaluation of the Employee Training and Development Process for Nicolet Area Technical College's Basic Education Program.

    ERIC Educational Resources Information Center

    Karl, Luis C.

    The adult basic education (ABE) program at Nicolet Area Technical College (NATC) evaluated its training and development (T&D) process for new basic education instructors. The study gathered monitoring and screening criteria that addressed valuable components for use in an instrument for validating effectiveness of the ABE program (T&D)…

  9. X-Ray Equipment and Protective Devices of Dental Assistant Programs in Pennsylvania Vocational Technical Schools. Vocational-Technical Education Research Report, Health Occupations, Monograph No. 7, Vol. 16, No. 1.

    ERIC Educational Resources Information Center

    Hominsky, Dolores J.; Hole, F. Marvin

    Objectives of a Pennsylvania study were (1) to investigate the ways in which the vocational technical schools of the state have met the recommendations of the Pennsylvania Department of Environmental Resources for classroom structural design and dental x-ray machines in dental assistant training programs and (2) to collect data on the methods by…

  10. CPTSC 2001: Managing Change and Growth in Technical and Scientific Communication. Proceedings of the Annual Conference of the Council for Programs in Technical and Scientific Communication (28th, Pittsburgh, Pennsylvania, October 11-13, 2001).

    ERIC Educational Resources Information Center

    Maylath, Bruce, Ed.

    This proceedings presents 43 papers delivered at the 2001 annual meeting of the Council for Programs in Technical and Scientific Communication (CPTSC). Papers in the proceedings include the following: "Act IV: On Being Less Invisible" (Bill Karis); "Building a Community of Professional Communicators by Mapping Needs and Assets"…

  11. Dental Assisting Program Guide.

    ERIC Educational Resources Information Center

    Georgia Univ., Athens. Dept. of Vocational Education.

    This program guide contains the standard dental assisting curriculum for technical institutes in Georgia. The curriculum encompasses the minimum competencies required for entry-level dental assistants, and includes job skills in the technical areas of preventive dentistry; four-handed dentistry; chairside assisting with emphasis in diagnostics,…

  12. Director's Discretionary Fund Report for Fiscal Year 1997

    NASA Technical Reports Server (NTRS)

    1998-01-01

    This technical memorandum contains brief technical papers describing research and technology development programs sponsored by the Ames Research Center Director's Discretionary Fund during fiscal year 1997 (October 1996 through September 1997). Appendices provide administrative information for each of the sponsored research programs.

  13. 2012 Missouri Local Technical Assistance Program (LTAP) at Missouri S&T.

    DOT National Transportation Integrated Search

    2013-05-01

    This annual report is a summary of the activities during 2012 for the Missouri Local Technical : Assistance Program (Missouri LTAP), which is located at Missouri University of Science and : Technology (Missouri S&T). It is submitted to the Missouri D...

  14. Director's discretionary fund report for fiscal year 1994

    NASA Technical Reports Server (NTRS)

    1995-01-01

    This technical memorandum contains brief technical papers describing research and technology development programs sponsored by the Ames Research Center Director's Discretionary Fund during fiscal year 1991 (October 1993 through September 1994). An appendix provides administrative information for each of the sponsored research programs.

  15. Director's Discretionary Fund report for FY 1993

    NASA Technical Reports Server (NTRS)

    1994-01-01

    This technical memorandum contains brief technical papers describing research and technology development programs sponsored by the Ames Research Center Director's Discretionary Fund during fiscal year 1993 (October 1992 through September 1993). An appendix provides administrative information for each of the sponsored research programs.

  16. A joint university-government technical editing program

    NASA Technical Reports Server (NTRS)

    Stohrer, Freda F.; Pinelli, Thomas E.

    1978-01-01

    The NASA Langley Research Center (LaRC) and Old Dominion University have designed a mutually useful technical editing program. A university team made up of an English instructor and two graduate students - one from English, one from engineering - works with a senior editor from LaRC to prepare technical reports for publication. A round-robin technique gives the university team editorial commentary from both language and technical specialists; the senior editor from LaRC supervises reports through final publication. To date, the system has provided LaRC with a respectable product and university students with valuable on-the-job training.

  17. The Changing Nature of Technical Assistance.

    ERIC Educational Resources Information Center

    Noggle, Nelson L.

    The changing nature of technical assistance activities and evaluation for compensatory education programs was discussed. The emphasis is on the Education Consolidation and Improvement Act (ECIA) Chapter 1 Technical Assistance Centers (TAC) and their clients. Improvement of school practices demands that the technical assistance process be developed…

  18. 78 FR 2284 - Methodology for Selecting Job Corps Centers for Closure; Comments Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-10

    ... (GED), and career technical training credentials, including industry-recognized credentials, state... align existing career technical training programs to technical standards established by industries or... technical training. Both PIPs and CAPs are used for continued monitoring and implemented for USDA and...

  19. 77 FR 52698 - 36(b)(1) Arms Sales Notification

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-30

    ... training equipment, publications and technical data, U.S. Government and contractor technical and logistics personnel services and other related elements of program and logistics support. (iv) Military Department..., publications and technical data, U.S. Government and contractor technical and logistics personnel services and...

  20. Training the Technical Editor.

    ERIC Educational Resources Information Center

    Cathcart, Margaret E.

    The demand for skilled technical editors is growing as society places increasing emphasis on receiving accurate, concise, and complete technical data. Since many organizations do not have inhouse programs for training technical editors, a need exists to provide inexperienced people with basic editing skills. One organization has developed two…

  1. Career-Technical Education--The Immediate Need for Work-Based Curriculum.

    ERIC Educational Resources Information Center

    Nee, John G.

    1994-01-01

    Career-technical education may be informal on-the-job training, organized workplace education, community college or technical institute programs, or apprenticeships, internships, and cooperative agreements. Another alternative is polytechnical education: providing technical and general studies for adults in existing school facilities after school…

  2. 24 CFR 901.235 - Technical assistance.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Technical assistance. 901.235... DEVELOPMENT PUBLIC HOUSING MANAGEMENT ASSESSMENT PROGRAM § 901.235 Technical assistance. (a) The Department may provide technical assistance to a PHA that is in substantial default. (b) The Department may...

  3. 48 CFR 825.902-70 - Technical assistance.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Technical assistance. 825... SOCIOECONOMIC PROGRAMS FOREIGN ACQUISITION Customs and Duties 825.902-70 Technical assistance. Should the... officer should contact the nearest U.S. Customs and Boarder Protection office for technical assistance...

  4. NASA scientific and technical information program multimedia initiative

    NASA Technical Reports Server (NTRS)

    Cotter, Gladys A.; Kaye, Karen

    1993-01-01

    This paper relates the experiences of the NASA Scientific and Technical Information Program in introducing multimedia within the STI Program framework. A discussion of multimedia technology is included to provide context for the STI Program effort. The STI Program's Multimedia Initiative is discussed in detail. Parallels and differences between multimedia and traditional information systems project development are highlighted. Challenges faced by the program in initiating its multimedia project are summarized along with lessons learned. The paper concludes with a synopsis of the benefits the program hopes to provide its users through the introduction of multimedia illustrated by examples of successful multimedia projects.

  5. MHD program plan, FY 1991

    NASA Astrophysics Data System (ADS)

    1990-10-01

    The current magnetohydrodynamic MHD program being implemented is a result of a consensus established in public meetings held by the Department of Energy in 1984. The public meetings were followed by the formulation of a June 1984 Coal-Fired MHD Preliminary Transition and Program Plan. This plan focused on demonstrating the proof-of-concept (POC) of coal-fired MHD electric power plants by the early 1990s. MHD test data indicate that while there are no fundamental technical barriers impeding the development of MHD power plants, technical risk remains. To reduce the technical risk three key subsystems (topping cycle, bottoming cycle, and seed regeneration) are being assembled and tested separately. The program does not require fabrication of a complete superconducting magnet, but rather the development and testing of superconductor cables. The topping cycle system test objectives can be achieved using a conventional iron core magnet system already in place at a DOE facility. Systems engineering-derived requirements and analytical modeling to support scale-up and component design guide the program. In response to environmental, economic, engineering, and utility acceptance requirements, design choices and operating modes are tested and refined to provide technical specifications for meeting commercial criteria. These engineering activities are supported by comprehensive and continuing systems analyses to establish realistic technical requirements and cost data. Essential elements of the current program are to: develop technical and environmental data for the integrated MHD topping cycle and bottoming cycle systems through POC testing (1000 and 4000 hours, respectively); design, construct, and operate a POC seed regeneration system capable of processing spent seed materials from the MHD bottoming cycle; prepare conceptual designs for a site specific MHD retrofit plant; and continue supporting research necessary for system testing.

  6. 47 CFR Appendix - Technical Appendix 2

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... PROGRAM Waiver of household eligibility. Pt. 301, App. 2 Technical Appendix 2 TECHNICAL APPENDIX 2—NTIA... promotional prices Equipment cannot be sold conditioned on the purchase of a Smart Antenna or other equipment...

  7. Scientific and technical information output of the Langley Research Center

    NASA Technical Reports Server (NTRS)

    1984-01-01

    Scientific and technical information that the Langley Research Center produced during the calendar year 1983 is compiled. Included are citations for Formal Reports, Quick-Release Technical Memorandums, Contractor Reports, Journal Articles and other Publications, Meeting Presentations, Technical Talks, Computer Programs, Tech Briefs, and Patents.

  8. 12 CFR 1805.303 - Technical assistance.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... proposes to become a CDFI. Such technical assistance may include training for management and other... 12 Banks and Banking 7 2010-01-01 2010-01-01 false Technical assistance. 1805.303 Section 1805.303... COMMUNITY DEVELOPMENT FINANCIAL INSTITUTIONS PROGRAM Use of Funds/Eligible Activities § 1805.303 Technical...

  9. 78 FR 44104 - Notice of Intent To Issue a Funding Opportunity Announcement; Technical Assistance

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-23

    ... Funding Opportunity Announcement; Technical Assistance AGENCY: Federal Energy Management Program, Office.... This notice also is to inform Federal agencies of the availability of technical assistance in advance.... FOR FURTHER INFORMATION CONTACT: For requests for technical assistance regarding CHP, please contact...

  10. 38 CFR 61.55 - Technical assistance reports.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... (CONTINUED) VA HOMELESS PROVIDERS GRANT AND PER DIEM PROGRAM § 61.55 Technical assistance reports. Each recipient of a technical assistance grant must submit to VA, quarterly, a report describing the activities... 38 Pensions, Bonuses, and Veterans' Relief 2 2011-07-01 2011-07-01 false Technical assistance...

  11. 38 CFR 61.55 - Technical assistance reports.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... (CONTINUED) VA HOMELESS PROVIDERS GRANT AND PER DIEM PROGRAM § 61.55 Technical assistance reports. Each recipient of a technical assistance grant must submit to VA, quarterly, a report describing the activities... 38 Pensions, Bonuses, and Veterans' Relief 2 2012-07-01 2012-07-01 false Technical assistance...

  12. 38 CFR 61.55 - Technical assistance reports.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... (CONTINUED) VA HOMELESS PROVIDERS GRANT AND PER DIEM PROGRAM § 61.55 Technical assistance reports. Each recipient of a technical assistance grant must submit to VA, quarterly, a report describing the activities... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Technical assistance...

  13. Adding Realism to Technical Drafting Programs

    ERIC Educational Resources Information Center

    Weaver, Gerald L.

    1976-01-01

    Suggestions for improved, relevant technical drafting programs are presented: (1) making realistic assignments, (2) viewing real projects, (3) duplicating industrial projects, (4) practicing lettering, (5) conducting research, (6) engaging in teamwork, (7) adapting to change, (8) learning to meet deadlines, and (9) stressing the importance of…

  14. Directory of Postsecondary Schools with Occupational Programs.

    ERIC Educational Resources Information Center

    Kay, Evelyn R.

    This directory of schools which provide occupational training lists public and private schools which offer programs in preparation for a specific career. The types of listings include schools classified as vocational/technical, business/commercial, cosmetology/barber, flight, arts/design, hospital, and allied health; technical institutes,…

  15. Directors's Discretionary Fund Report For Fiscal Year 1995

    NASA Technical Reports Server (NTRS)

    1996-01-01

    This technical memorandum contains brief technical papers describing research and technology development programs sponsored by the Ames Research Center Director's Discretionary Fund during the fiscal year 1995 (October 1994 through September 1995). An appendix provides administrative information for each of the sponsored research programs.

  16. 7 CFR 614.6 - Agency records and decision notices.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... notifies participants of the agency's preliminary and final technical determinations and program decisions... decision notice within 10 working days of rendering a technical determination or program decision. In lieu of certified mail, NRCS may hand deliver notices to participants with written acknowledgment of...

  17. Mapping the global health employment market: an analysis of global health jobs.

    PubMed

    Keralis, Jessica M; Riggin-Pathak, Brianne L; Majeski, Theresa; Pathak, Bogdan A; Foggia, Janine; Cullinen, Kathleen M; Rajagopal, Abbhirami; West, Heidi S

    2018-02-27

    The number of university global health training programs has grown in recent years. However, there is little research on the needs of the global health profession. We therefore set out to characterize the global health employment market by analyzing global health job vacancies. We collected data from advertised, paid positions posted to web-based job boards, email listservs, and global health organization websites from November 2015 to May 2016. Data on requirements for education, language proficiency, technical expertise, physical location, and experience level were analyzed for all vacancies. Descriptive statistics were calculated for the aforementioned job characteristics. Associations between technical specialty area and requirements for non-English language proficiency and overseas experience were calculated using Chi-square statistics. A qualitative thematic analysis was performed on a subset of vacancies. We analyzed the data from 1007 global health job vacancies from 127 employers. Among private and non-profit sector vacancies, 40% (n = 354) were for technical or subject matter experts, 20% (n = 177) for program directors, and 16% (n = 139) for managers, compared to 9.8% (n = 87) for entry-level and 13.6% (n = 120) for mid-level positions. The most common technical focus area was program or project management, followed by HIV/AIDS and quantitative analysis. Thematic analysis demonstrated a common emphasis on program operations, relations, design and planning, communication, and management. Our analysis shows a demand for candidates with several years of experience with global health programs, particularly program managers/directors and technical experts, with very few entry-level positions accessible to recent graduates of global health training programs. It is unlikely that global health training programs equip graduates to be competitive for the majority of positions that are currently available in this field.

  18. NASA scientific and technical program: User survey

    NASA Technical Reports Server (NTRS)

    Hunter, Judy F.; Shockley, Cynthia W.

    1993-01-01

    Results are presented of an intensive user requirements survey conducted by NASA's Scientific and Technical Information (STI) Program with the goal of improving the foundation for the user outreach program. The survey was carried out by interviewing 550 NASA scientists, engineers, and contractors and by analyzing 650 individual responses to a mailed out questionnaire. To analyze the user demographic data, a data base was built and used, and will be applied to ongoing analysis by the NASA STI Program.

  19. Specialized Study Options U.S.A., 1986-1988. A Guide to Short-Term Educational Programs in the United States for Foreign Nationals. Volume 1: Technical Education. Second Edition.

    ERIC Educational Resources Information Center

    Howard, Edrice, Ed.

    Information is provided on over 1,000 short-term programs offered by United States universities, trade and technical schools, and other organizations that are open to or designed for non-U.S. students. The programs, which range from 2 weeks to 1 year in length, require only a high school diploma as a prerequisite for enrollment. The programs are…

  20. Annual Technical Symposium (28th): Achieving Technical and Management Excellence. Held in Arlington, Virginia on April 11, 1991,

    DTIC Science & Technology

    1991-04-11

    Perplexed: Think Energy Again. Video Enhanced SECAT - An Energy Program; Quality Ship Service Power with an Integrated Diesel Electric Propulsion...DIesign Branch (5011), NAVSEA * "Think Energy Again! Video Enhanced SECAT - 5 An Energy Program"’ Hasan Pehlivan, Mechanical Engineer/Ship Trials, Surface...1.015, or 1.5% increase.) Association of Scientists and Engineers 28th Annual Technical Symposium, 11 April 1991 THINK ENERGY AGAIN! A VIDEO ENHANCED

  1. Configuration management program plan for Hanford site systems engineering

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hoffman, A.G.

    This plan establishes the integrated configuration management program for the evolving technical baseline developed through the systems engineering process. This configuration management program aligns with the criteria identified in the DOE Standard, DOE-STD-1073-93. Included are specific requirements for control of the systems engineering RDD-100 database, and electronic data incorporated in the database that establishes the Hanford site technical baseline.

  2. Adlai E. Stevenson High School Bilingual Academic and Technical Education for Youth Program (BATEY). O.E.E. Evaluation Report, 1981-1982.

    ERIC Educational Resources Information Center

    Bulkin, Elly; And Others

    The Bilingual Academic and Technical Education for Youth Program (BATEY) provides English as a second language (ESL) and bilingual instruction with a vocational focus to foreign born (98 percent of them Hispanic) students at Adlai E. Stevenson High School, Bronx, New York. Under the program, Title VII funds support administrative and support…

  3. Adlai E. Stevenson High School, Bilingual Academic and Technical Education for Youth Program. O.E.E. Evaluation Report, 1982-1983.

    ERIC Educational Resources Information Center

    Keyes, Jose Luis; Collins, Carla

    The Bilingual Academic and Technical Education for Youth (BATEY) Program completed its third and final year of funding at Adlai E. Stevenson High School, Bronx, New York. In 1982-83, the program offered bilingual instruction and support services to approximately 300 Hispanic students of limited English proficiency in grades 9-12. Although the…

  4. REPORT OF THE DIRECTOR OF A SHORT COURSE FOR SECONDARY SCHOOL COUNSELORS ON VOCATIONAL AND TECHNICAL TRAINING AND EMPLOYMENT OPPORTUNITIES.

    ERIC Educational Resources Information Center

    CHARLTON, HUEY E.

    A 6-WEEK TRAINING PROGRAM WAS CONDUCTED FOR SECONDARY SCHOOL COUNSELORS ON VOCATIONAL AND TECHNICAL TRAINING AND EMPLOYMENT OPPORTUNITIES. THE PROGRAM WAS DESIGNED TO FOCUS UPON THE PROBLEM OF EMPLOYMENT FACED BY YOUNG PEOPLE WHO ENTER THE LABOR MARKET PRIOR TO AND IMMEDIATELY AFTER COMPLETION OF HIGH SCHOOL. THE INSTRUCTIONAL PROGRAM CONSISTED OF…

  5. More than Colleagues: Tracing the Experiences of Career and Technical Education Instructors Engaged in Faculty-to-Faculty Mentoring Programs

    ERIC Educational Resources Information Center

    Findley, Daniel E.

    2012-01-01

    The purpose of this study was to understand the impact of faculty-to-faculty mentoring programs on the experiences of both mentors and first-year instructor proteges in Career and Technical Education (CTE) programs with an emphasis on practitioner-educators in nursing and in welding-fabrication. The study was undertaken for four reasons: (a)…

  6. Longitudinal Analysis of Student Performance between Host and Cooperating College Learners in the Dental Hygiene Program at Northcentral Technical College in Wausau, Wisconsin.

    ERIC Educational Resources Information Center

    Olmsted, Jodi L.

    The academic performance of students enrolled in a distance education dental hygiene program at Northcentral Technical College (NTC) in Wausau, Wisconsin, was analyzed in a comparative, quasi-experimental study. The study sample consisted of five cohorts of program graduates (students graduating in 1997-2001). The experiment groups were divided…

  7. INTEREST AND INTELLECTUAL INDICES RELATED TO SUCCESSFUL AND NON-SUCCESSFUL MALE COLLEGE STUDENTS IN TECHNICAL AND ASSOCIATE DEGREE PROGRAMS. FINAL REPORT.

    ERIC Educational Resources Information Center

    HECKER, DONALD L.; TAYLOR, RONALD G.

    THE PURPOSE OF THE PROJECT WAS TO STUDY THE DIFFERENCES AND SIMILARITIES IN INTEREST, ABILITY, AND PREVIOUS ACHIEVEMENT PATTERNS OF 941 MEN STUDENTS WHO ENROLLED IN VARIOUS TECHNICAL AND ASSOCIATE DEGREE 2-YEAR PROGRAMS AND TO DETERMINE WHICH VARIABLES COULD DIFFERENTIATE BETWEEN STUDENTS WHO COMPLETED, CHANGED TO AN ALTERNATE PROGRAM, OR WITHDREW…

  8. ORD Scientific and Engineering Technical Support for RPMs – Ground Water Technical Support Center

    EPA Science Inventory

    ORD Scientific and Engineering Technical Support for RPMs (and Others) is a hybrid informational and panel session that focuses on the technical support available from EPA’s Office of Research and Development (ORD) to RPMs and other EPA cleanup program staff. Examples of technica...

  9. 25 CFR 286.11 - Management and technical assistance.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false Management and technical assistance. 286.11 Section 286... DEVELOPMENT PROGRAM § 286.11 Management and technical assistance. (a) Prior to and concurrent with the making... insure that competent management and technical assistance is available to the grantee in the preparation...

  10. 25 CFR 286.11 - Management and technical assistance.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false Management and technical assistance. 286.11 Section 286... DEVELOPMENT PROGRAM § 286.11 Management and technical assistance. (a) Prior to and concurrent with the making... insure that competent management and technical assistance is available to the grantee in the preparation...

  11. 25 CFR 286.11 - Management and technical assistance.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 25 Indians 1 2012-04-01 2011-04-01 true Management and technical assistance. 286.11 Section 286.11... DEVELOPMENT PROGRAM § 286.11 Management and technical assistance. (a) Prior to and concurrent with the making... insure that competent management and technical assistance is available to the grantee in the preparation...

  12. 25 CFR 286.11 - Management and technical assistance.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false Management and technical assistance. 286.11 Section 286... DEVELOPMENT PROGRAM § 286.11 Management and technical assistance. (a) Prior to and concurrent with the making... insure that competent management and technical assistance is available to the grantee in the preparation...

  13. Career and Technical Education Administration: Requirements, Certification/Licensure, and Preparation

    ERIC Educational Resources Information Center

    Zirkle, Christopher J.; Jeffery, Jeremy O.

    2017-01-01

    The current climate of career and technical administration requirements in all 50 states was detailed and explored. An increasing number of states are not requiring specific career-technical administration certification/licensure in order to oversee secondary career and technical education (CTE) programs, with more states moving towards a general…

  14. Assessing Students' Technical Skill Attainment

    ERIC Educational Resources Information Center

    Jorgensen, Haley

    2010-01-01

    The Wisconsin Technical College System (WTCS) is working to comply with the Carl D. Perkins Career and Technical Education Improvement Act of 2006 (Perkins) to ensure that its graduates have mastered the technical skills needed by business and industry. The legislation requires that each state identify and approve program assessment strategies…

  15. 10 CFR 455.111 - Applicant certifications for technical assistance and energy conservation measure grants to...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 3 2010-01-01 2010-01-01 false Applicant certifications for technical assistance and... Institutions and Coordinating Agencies § 455.111 Applicant certifications for technical assistance and energy... for technical assistance programs and energy conservation measures, including renewable resource...

  16. 48 CFR 252.227-7016 - Rights in bid or proposal information.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... terms “technical data” and “computer software” are defined in the Rights in Technical Data—Noncommercial... delivery of technical data, the term “computer software” is defined in the Rights in Noncommercial Computer... Research Program, the Rights in Noncommercial Technical Data and Computer Software—Small Business...

  17. 48 CFR 252.227-7016 - Rights in bid or proposal information.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... terms “technical data” and “computer software” are defined in the Rights in Technical Data—Noncommercial... delivery of technical data, the term “computer software” is defined in the Rights in Noncommercial Computer... Research Program, the Rights in Noncommercial Technical Data and Computer Software—Small Business...

  18. 48 CFR 252.227-7016 - Rights in bid or proposal information.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... terms “technical data” and “computer software” are defined in the Rights in Technical Data—Noncommercial... delivery of technical data, the term “computer software” is defined in the Rights in Noncommercial Computer... Research Program, the Rights in Noncommercial Technical Data and Computer Software—Small Business...

  19. 48 CFR 252.227-7016 - Rights in bid or proposal information.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... terms “technical data” and “computer software” are defined in the Rights in Technical Data—Noncommercial... delivery of technical data, the term “computer software” is defined in the Rights in Noncommercial Computer... Research Program, the Rights in Noncommercial Technical Data and Computer Software—Small Business...

  20. 48 CFR 252.227-7016 - Rights in bid or proposal information.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... terms “technical data” and “computer software” are defined in the Rights in Technical Data—Noncommercial... delivery of technical data, the term “computer software” is defined in the Rights in Noncommercial Computer... Research Program, the Rights in Noncommercial Technical Data and Computer Software—Small Business...

  1. An Input Evaluation of Three Technical Assistance Needs Assessment Strategies.

    ERIC Educational Resources Information Center

    Suarez, Tanya M.; Cox, James O.

    The Technical Assistance Development System--TADS (a project to provide technical assistance to personnel implementing programs for preschool handicapped children and their families) conducted an evaluation of three technical assistance needs assessment strategies during 1979-80. The three strategies were: (1) on-site--conducted by a trained needs…

  2. Design and Assessment of an Associate Degree-Level Plant Operations Technical Education Program

    NASA Astrophysics Data System (ADS)

    Selwitz, Jason Lawrence

    Research was undertaken to develop and evaluate an associate degree-level technical education program in Plant Operations oriented towards training students in applied science, technology, engineering, and mathematics (STEM) skills and knowledge relevant to a spectrum of processing industries. This work focuses on four aspects of the curriculum and course development and evaluation research. First, the context of, and impetus for, what was formerly called vocational education, now referred to as technical or workforce education, is provided. Second, the research that was undertaken to design and evaluate an associate degree-level STEM workforce education program is described. Third, the adaptation of a student self-assessment of learning gains instrument is reviewed, and an analysis of the resulting data using an adapted logic model is provided, to evaluate the extent to which instructional approaches, in two process control/improvement-focused courses, were effective in meeting course-level intended learning outcomes. Finally, eight integrative multiscale exercises were designed from two example process systems, wastewater treatment and fast pyrolysis. The integrative exercises are intended for use as tools to accelerate the formation of an operator-technician's multiscale vision of systems, unit operations, underlying processes, and fundamental reactions relevant to multiple industries. Community and technical colleges serve a vital function in STEM education by training workers for medium- and high-skilled technical careers and providing employers the labor necessary to operate and maintain thriving business ventures. Through development of the curricular, course, and assessment-related instruments and tools, this research helps ensure associate degree-level technical education programs can engage in a continual process of program evaluation and improvement.

  3. National Aeronautics and Space Administration Scientific and Technical Information Programs.

    ERIC Educational Resources Information Center

    Pinelli, Thomas E., Ed.

    1990-01-01

    Eleven articles discuss informational and educational programs of the National Aeronautics and Space Administration (NASA). Some of the areas discussed include scientific and technical information management, the new Space and Earth Science Information Systems, transfer of technology to other industries, intellectual property issues, and the…

  4. ERD WATERSHED AND WATER QUALITY MODEL DEVELOPMENT AND TECHNICAL SUPPORT PROGRAM

    EPA Science Inventory

    The ERD has a long history in providing model research and development and technical support to Regions, States and the Office of Water for watersheds/water quality ecosystem research. The ERD efforts are described in major subtasks comprising the Program. Briefly, these are:

  5. 76 FR 17963 - Renewal of Agency Information Collection for Application for Job Placement and Training Services...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-31

    ... training program, which provides vocational/technical training, related counseling, guidance, job placement... the job placement and training program, which provides vocational/technical training, related... Application for Job Placement and Training Services; Request for Comments AGENCY: Bureau of Indian Affairs...

  6. Factors Affecting Training Effectiveness in Synchronous, Dispersed Virtual Environments

    DTIC Science & Technology

    2014-06-01

    technology to its technical training programs. Specifically, a distance learning model with instruction provided through 3-D virtual worlds could...ABSTRACT The U.S. Navy is investigating the feasibility of incorporating distance learning technology to its technical training programs. Specifically...15 A. TECHNOLOGY ACCEPTANCE MODEL

  7. Illinois Occupational Skill Standards: Chemical Process Technical Operators.

    ERIC Educational Resources Information Center

    Illinois Occupational Skill Standards and Credentialing Council, Carbondale.

    This document, which is intended for workforce preparation program providers, details the Illinois Occupational Skill Standards for programs preparing students for employment as chemical process technical operators. The document begins with a brief overview of the Illinois perspective on occupational skill standards and credentialing, the process…

  8. Mercer University's Graduate Certificate in Interactive Multimedia.

    ERIC Educational Resources Information Center

    Leonard, David C.

    Although most programs in technical communication reside in English departments where the focus is on writing, rhetoric, and exposition, the graduate certificate program in interactive multimedia at Mercer University is being developed for the Technical Communication Department within the School of Engineering. As a result, many of the…

  9. 77 FR 46658 - Proposed Priority; Technical Assistance To Improve State Data Capacity-National Technical...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-06

    ... percent of youth with individualized education programs (IEPs) graduating with a regular high school... 100,000 schools through EDFacts. \\4\\ Education Department General Administrative Regulations (EDGAR... Department programs (e.g., Consolidated State Performance Report under the Elementary and Secondary Education...

  10. 75 FR 42181 - Notice of Funding Availability for the Small Business Transportation Resource Center Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-20

    ... of 20 hours of individual or group counseling sessions to small businesses per month. (D) Planning... training programs, such as, business assessment, management training, counseling, technical assistance... business counseling, and technical assistance with small businesses currently doing business with public...

  11. 76 FR 30990 - Notice of Funding Availability for the Small Business Transportation Resource Center Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-27

    ... contracts and subcontracts portfolio. 3. Provide a minimum of 20 hours of individual or group counseling... training programs, such as, business assessment, management training, counseling, technical assistance... information dissemination, small business counseling, and technical assistance with small businesses currently...

  12. 75 FR 23319 - Notice of Funding Availability for the Small Business Transportation Resource Center Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-03

    ... contracts and subcontracts portfolio. 3. Provide a minimum of 20 hours of individual or group counseling... programs, such as, business assessment, management training, counseling, technical assistance, marketing... dissemination, small business counseling, and technical assistance with small businesses currently doing...

  13. Advancing Next-Generation Energy in Indian Country (Fact Sheet)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    This fact provides information on the Strategic Technical Assistance Response Team (START) Program, a U.S. Department of Energy Office of Indian Energy Policy and Programs (DOE-IE) initiative to provide technical expertise to support the development of next-generation energy projects in Indian Country.

  14. Advancing Energy Development in Indian Country (Fact Sheet)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    This fact sheet provides information on the Strategic Technical Assistance Response Team (START) Program, a U.S. Department of Energy Office of Indian Energy Policy and Programs (DOE-IE) initiative to provide technical expertise to support the development of next-generation energy projects in Indian Country.

  15. 7 CFR 2003.18 - Functional organization of RHS.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... and 504 Rural Housing direct and guaranteed loan and grant programs, Rural Housing and Self-Help Site loans, the Self-Help Technical Assistance grant program, Housing Application Packaging and Technical and Supervisory Assistance grants, and Home Improvement and Repaid loans and grants. The office directs the...

  16. 7 CFR 2003.18 - Functional organization of RHS.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... and 504 Rural Housing direct and guaranteed loan and grant programs, Rural Housing and Self-Help Site loans, the Self-Help Technical Assistance grant program, Housing Application Packaging and Technical and Supervisory Assistance grants, and Home Improvement and Repaid loans and grants. The office directs the...

  17. 7 CFR 2003.18 - Functional organization of RHS.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... and 504 Rural Housing direct and guaranteed loan and grant programs, Rural Housing and Self-Help Site loans, the Self-Help Technical Assistance grant program, Housing Application Packaging and Technical and Supervisory Assistance grants, and Home Improvement and Repaid loans and grants. The office directs the...

  18. 7 CFR 2003.18 - Functional organization of RHS.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... and 504 Rural Housing direct and guaranteed loan and grant programs, Rural Housing and Self-Help Site loans, the Self-Help Technical Assistance grant program, Housing Application Packaging and Technical and Supervisory Assistance grants, and Home Improvement and Repaid loans and grants. The office directs the...

  19. Enhancing Tribal Energy Security and Clean Energy (Fact Sheet)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    This fact provides information on the Strategic Technical Assistance Response Team (START) Program, a U.S. Department of Energy Office of Indian Energy Policy and Programs (DOE-IE) initiative to provide technical expertise to support the development of next-generation energy projects in Indian Country.

  20. Modernizing Career and Technical Education Programs

    ERIC Educational Resources Information Center

    Drage, Karen

    2009-01-01

    High-quality career and technical education (CTE) programs can launch America's future competitiveness through increased student engagement, the innovative integration of traditional academic courses, and by meeting the needs of both employers and the economy as a whole. American students failing to keep pace with their international counterparts…

  1. 78 FR 20503 - Energy Conservation Program: Availability of the Interim Technical Support Document for High...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-05

    ... Conservation Program: Availability of the Interim Technical Support Document for High-Intensity Discharge Lamps... high-intensity discharge (HID) lamps energy conservation standards in the Federal Register. This... interim analysis for high- intensity discharge lamps energy conservation standards. The notice provided...

  2. GPA/GPSA/OSU-Okmulgee natural gas compression technician training program

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Doede, S.

    Approximately one year ago, OSU-Okmulgee and the Gas Processors Association began discussions about the possibility of developing a natural Gas Technician Training Program for GPA members. Following a presentation to the Membership and Services Committee, Chairman John Ehlers solicited and obtained the approval of the GPA Executive Committee to sponsor the program. Participation in the program was also made available to GPSA members. The purpose of the program is to upgrade the technical competency and professional level of incoming natural gas compression technicians. It educates students to analytically diagnose, service and maintain gas compression equipment and systems using industry recommendedmore » procedures, special tools and service information. It also provides course content, which will enable successful graduates to advance in position after additional experience, and to understand new systems, technologies and components as they are introduced. The two-year Associate-In-Applied Science Degree program includes six successive college semesters. Nearly one-half of the time is designated for technical/academic education at Oklahoma State University-Okmulgee with the balance of time allocated for on-the-job internship experiences at sponsoring GPA/GPSA members. Each block of technical education and general education course work is followed by an immediate work experience time period designated to reinforce the technical and general education. These time periods are approximately seven and one-half weeks in length each. It is essential for the success of the students and the program that the students' education at OSU-Okmulgee and work experiences at GPA/GPSA member facilities be closely aligned for maximum student learning and retention. In addition to technical classes on gas compression equipment and components, the courses offered in math, speech, technical writing, psychology and ethics for example, prepare students to be able to communicate well, get along with others and be responsible and productive employees.« less

  3. 1998 NASA-ASEE-Stanford Summer Faculty Fellowship Program

    NASA Technical Reports Server (NTRS)

    1998-01-01

    This report presents the essential features and highlights of the 1998 Summer Faculty Fellowship Program at Ames Research Center and Dryden Flight Research Center in a comprehensive and concise form. Summary reports describing the fellows' technical accomplishments are enclosed in the attached technical report. The proposal for the 1999 NASA-ASEE-Stanford Summer Faculty Fellowship Program is being submitted under separate cover. Of the 31 participating fellows, 27 were at Ames and 4 were at Dryden. The Program's central feature is the active participation by each fellow in one of the key technical activities currently under way at either the NASA Ames Research Center or the NASA Dryden Flight Research Center. The research topic is carefully chosen in advance to satisfy the criteria of: (1) importance to NASA, (2) high technical level, and (3) a good match to the interests, ability, and experience of the fellow, with the implied possibility of NASA-supported follow-on work at the fellow's home institution. Other features of the Summer Faculty Fellowship Program include participation by the fellows in workshops and seminars at Stanford, the Ames Research Center, and other off-site locations. These enrichment programs take place either directly or remotely, via the Stanford Center for Professional Development, and also involve specific interactions between fellows and Stanford faculty on technical and other academic subjects. A few, brief remarks are in order to summarize the fellows' opinions of the summer program. It is noteworthy that 90% of the fellows gave the NASA-Ames/Dryden- Stanford program an "excellent" rating and the remaining 10%, "good." Also, 100% would recommend the program to their colleagues as an effective means of furthering their professional development as teachers and researchers. Last, but not least, 87% of the fellows stated that a continuing research relationship with their NASA colleagues' organization probably would be maintained. Therefore, the NASA-ASEE- Ames/Dryden-Stanford Program has met its goals very well and every effort will be made to continue to do so in the future.

  4. 1996 DOE technical standards program workshop: Proceedings

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    1996-07-01

    The workshop theme is `The Strategic Standardization Initiative - A Technology Exchange and Global Competitiveness Challenge for DOE.` The workshop goal is to inform the DOE technical standards community of strategic standardization activities taking place in the Department, other Government agencies, standards developing organizations, and industry. Individuals working on technical standards will be challenged to improve cooperation and communications with the involved organizations in response to the initiative. Workshop sessions include presentations by representatives from various Government agencies that focus on coordination among and participation of Government personnel in the voluntary standards process; reports by standards organizations, industry, and DOEmore » representatives on current technology exchange programs; and how the road ahead appears for `information superhighway` standardization. Another session highlights successful standardization case studies selected from several sites across the DOE complex. The workshop concludes with a panel discussion on the goals and objectives of the DOE Technical Standards Program as envisioned by senior DOE management. The annual workshop on technical standards has proven to be an effective medium for communicating information related to standards throughout the DOE community. Technical standards are used to transfer technology and standardize work processes to produce consistent, acceptable results. They provide a practical solution to the Department`s challenge to protect the environment and the health and safety of the public and workers during all facility operations. Through standards, the technologies of industries and governments worldwide are available to DOE. The DOE Technical Standards Program, a Department-wide effort that crosscuts all organizations and disciplines, links the Department to those technologies.« less

  5. Effective Synthesis of Sulfate Metabolites of Chlorinated Phenols

    PubMed Central

    Lehmler, Hans-Joachim; He, Xianran; Li, Xueshu; Duffel, Michael W.; Parkin, Sean

    2013-01-01

    Chlorophenols are an important class of persistent environmental contaminants and have been implicated in a range of adverse health effects, including cancer. They are readily conjugated and excreted as the corresponding glucuronides and sulfates in the urine of humans and other species. Here we report the synthesis and characterization of a series of ten chlorophenol sulfates by sulfation of the corresponding chlorophenols with 2,2,2-trichloroethyl (TCE) chlorosulfate using N,N-dimethylaminopyridine (DMAP) as base. Deprotection of the chlorophenol diesters with zinc powder/ammonium formate yielded the respective chlorophenol sulfate ammonium salts in good yield. The molecular structure of three TCE-protected chlorophenol sulfate diesters and one chlorophenol sulfate monoester were confirmed by X-ray crystal structure analysis. The chlorophenol sulfates were stable for several months if stored at −20 °C and, thus, are useful for future toxicological, environmental and human biomonitoring studies. PMID:23906814

  6. Piezoelectric Actuator Modeling Using MSC/NASTRAN and MATLAB

    NASA Technical Reports Server (NTRS)

    Reaves, Mercedes C.; Horta, Lucas G.

    2003-01-01

    This paper presents a procedure for modeling structures containing piezoelectric actuators using MSCMASTRAN and MATLAB. The paper describes the utility and functionality of one set of validated modeling tools. The tools described herein use MSCMASTRAN to model the structure with piezoelectric actuators and a thermally induced strain to model straining of the actuators due to an applied voltage field. MATLAB scripts are used to assemble the dynamic equations and to generate frequency response functions. The application of these tools is discussed using a cantilever aluminum beam with a surface mounted piezoelectric actuator as a sample problem. Software in the form of MSCINASTRAN DMAP input commands, MATLAB scripts, and a step-by-step procedure to solve the example problem are provided. Analysis results are generated in terms of frequency response functions from deflection and strain data as a function of input voltage to the actuator.

  7. Modeling epidemics on adaptively evolving networks: A data-mining perspective.

    PubMed

    Kattis, Assimakis A; Holiday, Alexander; Stoica, Ana-Andreea; Kevrekidis, Ioannis G

    2016-01-01

    The exploration of epidemic dynamics on dynamically evolving ("adaptive") networks poses nontrivial challenges to the modeler, such as the determination of a small number of informative statistics of the detailed network state (that is, a few "good observables") that usefully summarize the overall (macroscopic, systems-level) behavior. Obtaining reduced, small size accurate models in terms of these few statistical observables--that is, trying to coarse-grain the full network epidemic model to a small but useful macroscopic one--is even more daunting. Here we describe a data-based approach to solving the first challenge: the detection of a few informative collective observables of the detailed epidemic dynamics. This is accomplished through Diffusion Maps (DMAPS), a recently developed data-mining technique. We illustrate the approach through simulations of a simple mathematical model of epidemics on a network: a model known to exhibit complex temporal dynamics. We discuss potential extensions of the approach, as well as possible shortcomings.

  8. Experiences with the use of axisymmetric elements in cosmic NASTRAN for static analysis

    NASA Technical Reports Server (NTRS)

    Cooper, Michael J.; Walton, William C.

    1991-01-01

    Discussed here are some recent finite element modeling experiences using the axisymmetric elements CONEAX, TRAPAX, and TRIAAX, from the COSMIC NASTRAN element library. These experiences were gained in the practical application of these elements to the static analysis of helicopter rotor force measuring systems for two design projects for the NASA Ames Research Center. These design projects were the Rotor Test Apparatus and the Large Rotor Test Apparatus, which are dedicated to basic helicopter research. Here, a genetic axisymmetric model is generated for illustrative purposes. Modeling considerations are discussed, and the advantages and disadvantages of using axisymmetric elements are presented. Asymmetric mechanical and thermal loads are applied to the structure, and single and multi-point constraints are addressed. An example that couples the axisymmetric model to a non-axisymmtric model is demonstrated, complete with DMAP alters. Recommendations for improving the elements and making them easier to use are offered.

  9. In vivo quantification of amyloid burden in TTR-related cardiac amyloidosis

    PubMed Central

    Kollikowski, Alexander Marco; Kahles, Florian; Kintsler, Svetlana; Hamada, Sandra; Reith, Sebastian; Knüchel, Ruth; Röcken, Christoph; Mottaghy, Felix Manuel; Marx, Nikolaus; Burgmaier, Mathias

    2017-01-01

    Summary Cardiac transthyretin-related (ATTR) amyloidosis is a severe cardiomyopathy for which therapeutic approaches are currently under development. Because non-invasive imaging techniques such as cardiac magnetic resonance imaging and echocardiography are non-specific, the diagnosis of ATTR amyloidosis is still based on myocardial biopsy. Thus, diagnosis of ATTR amyloidosis is difficult in patients refusing myocardial biopsy. Furthermore, myocardial biopsy does not allow 3D-mapping and quantification of myocardial ATTR amyloid. In this report we describe a 99mTc-DPD-based molecular imaging technique for non-invasive single-step diagnosis, three-dimensional mapping and semiquantification of cardiac ATTR amyloidosis in a patient with suspected amyloid heart disease who initially rejected myocardial biopsy. This report underlines the clinical value of SPECT-based nuclear medicine imaging to enable non-invasive diagnosis of cardiac ATTR amyloidosis, particularly in patients rejecting biopsy. PMID:29259858

  10. Implementation of the block-Krylov boundary flexibility method of component synthesis

    NASA Technical Reports Server (NTRS)

    Carney, Kelly S.; Abdallah, Ayman A.; Hucklebridge, Arthur A.

    1993-01-01

    A method of dynamic substructuring is presented which utilizes a set of static Ritz vectors as a replacement for normal eigenvectors in component mode synthesis. This set of Ritz vectors is generated in a recurrence relationship, which has the form of a block-Krylov subspace. The initial seed to the recurrence algorithm is based on the boundary flexibility vectors of the component. This algorithm is not load-dependent, is applicable to both fixed and free-interface boundary components, and results in a general component model appropriate for any type of dynamic analysis. This methodology was implemented in the MSC/NASTRAN normal modes solution sequence using DMAP. The accuracy is found to be comparable to that of component synthesis based upon normal modes. The block-Krylov recurrence algorithm is a series of static solutions and so requires significantly less computation than solving the normal eigenspace problem.

  11. A general low frequency acoustic radiation capability for NASTRAN

    NASA Technical Reports Server (NTRS)

    Everstine, G. C.; Henderson, F. M.; Schroeder, E. A.; Lipman, R. R.

    1986-01-01

    A new capability called NASHUA is described for calculating the radiated acoustic sound pressure field exterior to a harmonically-excited arbitrary submerged 3-D elastic structure. The surface fluid pressures and velocities are first calculated by coupling a NASTRAN finite element model of the structure with a discretized form of the Helmholtz surface integral equation for the exterior fluid. After the fluid impedance is calculated, most of the required matrix operations are performed using the general matrix manipulation package (DMAP) available in NASTRAN. Far field radiated pressures are then calculated from the surface solution using the Helmholtz exterior integral equation. Other output quantities include the maximum sound pressure levels in each of the three coordinate planes, the rms and average surface pressures and normal velocities, the total radiated power and the radiation efficiency. The overall approach is illustrated and validated using known analytic solutions for submerged spherical shells subjected to both uniform and nonuniform applied loads.

  12. Design and Concept of Polyzwitterionic Copolymer Microgel Drug Delivery Systems In Situ Loaded with Non-steroidal Anti-inflammatory Ibuprofen.

    PubMed

    Kostova, Bistra; Kamenska, Elena; Georgieva, Dilyana; Balashev, Konstantin; Rachev, Dimitar; Georgiev, George

    2017-01-01

    Nowadays, the modern pharmaceutical investigations are directed toward obtaining of new polymer micro- and nano-sized drug delivery carriers. In this respect, the use of hydrogel carriers based on polyzwitterions (PZIs) is an opportunity in the preparation of polymer drug delivery systems with desired characteristics. This paper describes the synthesis and characterization of micro-structured p(VA-co-DMAPS) systems with different compositions in situ loaded with Ibuprofen by emulsifier-free emulsion copolymerization (EEC) in water. The mean size of the prepared microparticles was measured by SEM and particles have been visualized by AFM. The inclusion of Ibuprofen in the polyzwitterionic copolymer microgel systems was established by using DSC. In vitro drug release experiments were carried out in order to estimate the ability of the obtained microgels to modify the release of water-insoluble Ibuprofen.

  13. Fingerprinting of Materials: Technical Supplement

    NASA Technical Reports Server (NTRS)

    Workman, Gary L.

    1992-01-01

    This supplement to the Guidelines for Maintaining a Chemical Fingerprinting Program has been developed to assist NASA personnel, contractors, and sub-contractors in defining the technical aspects and basic concepts which can be used in chemical fingerprinting programs. This material is not meant to be totally inclusive to all chemical fingerprinting programs, but merely to present current concepts. Each program will be tailored to meet the needs of the individual organizations using chemical fingerprinting to improve their quality and reliability in the production of aerospace systems.

  14. College Graduation Rates for Minority Students in a Selective Technical University: Will Participation in a Summer Bridge Program Contribute to Success?

    PubMed

    Murphy, Terrence E; Gaughan, Monica; Hume, Robert; Moore, S Gordon

    2010-03-01

    There are many approaches to solving the problem of underrepresentation of some racial and ethnic groups and women in scientific and technical disciplines. Here, the authors evaluate the association of a summer bridge program with the graduation rate of underrepresented minority (URM) students at a selective technical university. They demonstrate that this 5-week program prior to the fall of the 1st year contains elements reported as vital for successful student retention. Using multivariable survival analysis, they show that for URM students entering as fall-semester freshmen, relative to their nonparticipating peers, participation in this accelerated summer bridge program is associated with higher likelihood of graduation. The longitudinal panel data include more than 2,200 URM students.

  15. College Graduation Rates for Minority Students in a Selective Technical University: Will Participation in a Summer Bridge Program Contribute to Success?

    PubMed Central

    Murphy, Terrence E.; Gaughan, Monica; Hume, Robert; Moore, S. Gordon

    2012-01-01

    There are many approaches to solving the problem of underrepresentation of some racial and ethnic groups and women in scientific and technical disciplines. Here, the authors evaluate the association of a summer bridge program with the graduation rate of underrepresented minority (URM) students at a selective technical university. They demonstrate that this 5-week program prior to the fall of the 1st year contains elements reported as vital for successful student retention. Using multivariable survival analysis, they show that for URM students entering as fall-semester freshmen, relative to their nonparticipating peers, participation in this accelerated summer bridge program is associated with higher likelihood of graduation. The longitudinal panel data include more than 2,200 URM students. PMID:23136456

  16. 76 FR 50474 - Special Demonstration Programs-National Technical Assistance Projects To Improve Employment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-15

    ... its vocational rehabilitation (VR) programs. We intend the priority to increase the transfer... the field of rehabilitation that have national significance and to improve the performance of State VR... Technical Assistance and Continuing Education (TACE) centers, and State VR agencies. For example, the...

  17. Outdoor Leadership Evaluation: Nature and Scope of the Problem.

    ERIC Educational Resources Information Center

    James, Leroy M.

    Beyond the ability to exhibit good judgment and common sense while performing duties as a leader under stress and pressure, an outdoor adventure program leader should possess technical skills, human relations skills, and philosophical understanding of outdoor programming. Technical skills include knowledge of initiatives/ropes course activities,…

  18. Physically Healthy and Ready to Learn. Technical Assistance Paper No. 1

    ERIC Educational Resources Information Center

    US Department of Health and Human Services, Head Start Bureau, 2006

    2006-01-01

    This Technical Assistance Paper offers guidance to programs regarding the implementation of the "Head Start Program Performance Standards" on child health and developmental services, child health and safety, and child nutrition. The paper examines how physical health influences children's development and how child health and development…

  19. Technical and Management Information System (TMIS)

    NASA Technical Reports Server (NTRS)

    Rau, Timothy R.

    1987-01-01

    The TMIS goals developed to support the Space Station Program (SSP) mission requirements are outlined. The TMIS will provide common capabilities to all SSP centers and facilitate the flow of technical and management information throughout the program as well as SSP decision-making processes. A summary is presented of the various TMIS phases.

  20. Analysis of Florida Department of Transportation transit corridor program/projects : technical memorandum number one - review and summary of transit corridor plans

    DOT National Transportation Integrated Search

    2001-05-01

    The purpose of this project was to undertake a consolidated comprehensive review of the Florida Department of Transportation Transit Corridor Program. Technical Memorandum Number One provides a summary of all transit corridor projects either under wa...

  1. 76 FR 66763 - Models for Plant-Specific Adoption of Technical Specifications Task Force Traveler TSTF-510...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-27

    ... of Technical Specifications Task Force Traveler TSTF-510, Revision 2, ``Revision to Steam Generator..., Revision 2, ``Revision to Steam Generator [(SG)] Program Inspection Frequencies and Tube Sample Selection..., ``Steam Generator (SG) Program,'' Specification 5.6.7, ``Steam Generator Tube Inspection Report,'' and the...

  2. Taxonomy of Behavioral Objectives for Vocational Programs. Vol. I.

    ERIC Educational Resources Information Center

    Gloucester County Vocational-Technical School, Sewell, NJ.

    Developed from courses of study in two-year vocational technical programs at the Gloucester County Vocational Technical School, these taxonomies present behavioral objectives for 12 subjects. They are intended for use by vocational teachers in the preparation of the vocational component of the individualized educational plan (IEP) for special…

  3. Teaching Technical Report Writing

    ERIC Educational Resources Information Center

    De Pasquale, Joseph A.

    1977-01-01

    A high school electronics teacher describes the integration of technical report writing in the electronics program for trade and industrial students. He notes that the report writing rather than just recording data seemed to improve student laboratory experience but further improvements in the program are needed. A sample lab report is included.…

  4. Annual Report, 1979-1980. New York City Technical College.

    ERIC Educational Resources Information Center

    New York City Technical Coll., Brooklyn. Div. of Continuing Education and Extension Services.

    Funding, enrollments, and outcomes are reported for the programs offered during 1979-1980 by New York City Technical College's Division of Continuing Education and Extension Services. The report's introduction analyzes enrollment in the division, summarizes external evaluation of selected programs, and examines problems of staffing, space, and the…

  5. Student Flow Model SFM-IA: System Documentation. Technical Report 41B. Preliminary Edition.

    ERIC Educational Resources Information Center

    Busby, John C.; Johnson, Richard S.

    Technical specifications, operating procedures, and reference information for the National Center for Higher Education Management Systems' (NCHEMS) Student Flow Model (SFM) computer programs are presented. Included are narrative descriptions of the system and its modules, specific program documentation for each of the modules, system flowcharts,…

  6. Improving Vocational Education in Post-High School Institutions. Final Report.

    ERIC Educational Resources Information Center

    MacArthur, Earl W.

    Four ongoing programs in postsecondary vocational-technical education were examined in a national institute attended by 59 representatives from 31 states. Institutions reporting programs were: (1) Los Angeles Trade and Technical College, California, (2) Washtenaw Community College, Ann Arbor, Michigan, (3) Rockingham Community College, Wentworth,…

  7. OUTLINE OF VOCATIONAL TRAINING IN ZAMBIA.

    ERIC Educational Resources Information Center

    Australian Dept. of Labour and National Service, Perth.

    THE 1963 POPULATION OF ZAMBIA WAS APPROXIMATELY 3.5 MILLION. THE 8-YEAR PRIMARY EDUCATION PROGRAM IS FOLLOWED BY SECONDARY, SECONDARY TECHNICAL, AND TRADE SCHOOL OPTIONS. THERE IS AN INCREASE IN ADULT EDUCATION AT THE PRIMARY AND SECONDARY LEVELS. CRAFT AND TECHNICIAN LEVEL PROGRAMS ARE CONDUCTED AT NORTHERN TECHNICAL COLLEGE AND ITS ANCILLARY…

  8. Improving Sex Equity in Postsecondary Vocational/Technical Programs: A Resource Manual.

    ERIC Educational Resources Information Center

    Lovelace, Bill E.; And Others

    This manual was developed to assist postsecondary administrators, faculty, staff, and students by providing materials specifically designed to eliminate sex bias and stereotyping of students and to recruit students into nontraditional careers and vocational-technical programs. The manual is organized in six sections. The first section introduces…

  9. Education of Technicians for Water Conservation and Wastewater Control.

    ERIC Educational Resources Information Center

    Brooking, Walter J.

    There is a growing need for supportive personnel with technical preparation in water and wastewater purification and water resource conservation. A curriculum and program guide was developed in 1965-66 by Fayetteville Technical Institute for use by institutions interested in establishing a program to educate technicians. Meeting the need for…

  10. Ohio Agricultural Business and Production Systems. Technical Competency Profile (TCP).

    ERIC Educational Resources Information Center

    Ray, Gayl M.; Kershaw, Isaac; Mokma, Arnie

    This document describes the essential competencies from secondary through post-secondary associate degree programs for a career in agricultural business and production systems. Following an introduction, the Ohio College Tech Prep standards and program, and relevant definitions are described. Next are the technical competency profiles for these…

  11. Preparing CATE Leaders Online

    ERIC Educational Resources Information Center

    Blank, Bill; Hernandez, Victor

    2008-01-01

    Like most institutions offering programs for career and technical educators, the University of South Florida (USAF) has experienced the impact of changes in the field. Thirty years ago there were undergraduate and graduate programs in career and technical education (CATE) at every university in the Florida state system involving more than 50…

  12. Career Pathways in Indiana

    ERIC Educational Resources Information Center

    McCaskey, Steve; Johnson, Tricia

    2010-01-01

    The revisions to the Carl D. Perkins Career and Technical Education Act of 2006 require that career and technical education (CTE) programs provide students with a clear pathway from secondary to postsecondary education, and into high-wage, high-skill and high-demand careers. States nationwide are developing programs, called career pathways, to…

  13. DOE scientific and technical information management

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Beasly, M.

    The objective of this paper was a discussion of the mission objectives and program activities of the DOE Office of Scientific and Technical Information. Topics of discussion were: (1) program direction and structure; (2) representation in gov`t and international organizations; (3) management of information; and (4) consultation and assistance.

  14. Missouri local technical assistance program at Missouri University of Science and Technology (formerly University of Missouri--Rolla) : annual progress report January-December 2007.

    DOT National Transportation Integrated Search

    2009-02-01

    This annual report is a summary of the activities during 2007 for the Missouri Local Technical Assistance Program (Missouri LTAP), which is located at Missouri University of Science and Technology. The report highlights Missouri LTAPs performance ...

  15. National Data Program for the Marine Environment Technical Development Plan. Final Report, Volume Two.

    ERIC Educational Resources Information Center

    System Development Corp., Santa Monica, CA.

    A national data program for the marine environment is recommended. Volume 2 includes: (1) objectives, scope, and methodology; (2) summary of the technical development plan; (3) agency development plans - Great Lakes and coastal development and (4) marine data network development plans. (Author)

  16. Seven Personal Accounts from the 2012 ACTE Fellowship Team

    ERIC Educational Resources Information Center

    Strebe, Connie; Mosley, Chaney; Biggerstaff, Patrick; Cox, Lynne Cagle; Williams, Hershel; Lindsley, Dawn; Umehira, Ron

    2013-01-01

    Each year since 2009, the Association for Career and Technical Education (ACTE) has supported the National Leadership Fellowship Program. This program is geared towards individuals with a desire not only to develop their own leadership skills, but also to become advocates for career and technical education (CTE). Responsibilities and expectations…

  17. Stafford Technical Center: Designing a Future for Architects and Builders

    ERIC Educational Resources Information Center

    Lucci, William, Jr.

    2005-01-01

    The Engineering Technology Academy (ETA) program at Stafford Technical Center in Rutland, Vermont, offers benefits beyond the conventional high school learning experience. In September, at the beginning of the program, students learn the traditional skills of using tools, line weights and lettering. Once they develop these basic skills, students…

  18. [Assessment of the Space Station Program

    NASA Technical Reports Server (NTRS)

    Kerrebrock, Jack L.

    1994-01-01

    This letter report by the National Research Council's (NRC's) Aeronautics and Space Engineering Board addresses comments on NASA's response to the Board's 1993 letter report, NASA's response to technical and management recommendations from previous NRC technical reports on the Space Station, and an assessment of the current International Space Station Alpha (ISSA) program.

  19. NASA STI Program Coordinating Council Twelfth Meeting: Standards

    NASA Technical Reports Server (NTRS)

    1994-01-01

    The theme of this NASA Scientific and Technical Information Program Coordinating Council Meeting was standards and their formation and application. Topics covered included scientific and technical information architecture, the Open Systems Interconnection Transmission Control Protocol/Internet Protocol, Machine-Readable Cataloging (MARC) open system environment procurement, and the Government Information Locator Service.

  20. NASA STI Program Seminar: Electronic documents

    NASA Technical Reports Server (NTRS)

    1994-01-01

    The theme of this NASA Scientific and Technical Information Program Seminar was electronic documents. Topics covered included Electronic Documents Management at the CASI, the Impact of Electronic Publishing on User Expectations and Searching Image Record Management, Secondary Publisher Considerations for Electronic Journal Literature, and the Technical Manual Publishing On Demand System (TMPODS).

  1. 2015-2016 Florida Adult Education Assessment Technical Assistance Paper

    ERIC Educational Resources Information Center

    Florida Department of Education, 2016

    2016-01-01

    This technical assistance paper provides guidance to individuals with test administration responsibilities in adult education programs. These policies apply to the approved assessments that programs may use to report educational gains in compliance with the National Reporting System (NRS) requirements. The NRS is the accountability system for the…

  2. 2016-2017 Florida Adult Education Assessment Technical Assistance Paper

    ERIC Educational Resources Information Center

    Florida Department of Education, 2017

    2017-01-01

    This technical assistance paper provides guidance to individuals with test administration responsibilities in adult education programs. These policies apply to the approved assessments that programs may use to report educational gains in compliance with the National Reporting System (NRS) requirements. The NRS is the accountability system for the…

  3. TADS Final Evaluation Report, 1980-81. Appendix S.

    ERIC Educational Resources Information Center

    Suarez, Tanya M.; And Others

    The document contains the final report of the Technical Assistance Development System (TADS), a program which provided technical assistance (TA) services to 53 Handicapped Children's Early Education Program (HCEEP) demonstration projects and 13 State Implementation Grants (SIGs). The evaluation report is divided into five sections. Section 1…

  4. 77 FR 18999 - New Mexico Collaborative Forest Restoration Program Technical Advisory Panel

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-29

    ... Collaborative Forest Restoration Program Technical Advisory Panel will meet in Albuquerque, New Mexico. The... the Hyatt Place Albuquerque/ Uptown, 6901 Arvada Avenue NE., Albuquerque, NM 87110, (505) 872-9000... Service, 333 Broadway SE., Albuquerque, NM 87102. Comments may also be sent via email to [email protected

  5. 75 FR 34973 - New Mexico Collaborative Forest Restoration Program Technical Advisory Panel

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-21

    ... Collaborative Forest Restoration Program Technical Advisory Panel will meet in Albuquerque, New Mexico. The... meeting will be held at the Hyatt Place Albuquerque/ Uptown, 6901 Arvada Avenue, NE., Albuquerque, NM... International Forestry Staff, USDA Forest Service, 333 Broadway SE., Albuquerque, NM 87102. Comments may also be...

  6. Iridium: failures & successes

    NASA Astrophysics Data System (ADS)

    Christensen, CarissaBryce; Beard, Suzette

    2001-03-01

    This paper will provide an overview of the Iridium business venture in terms of the challenges faced, the successes achieved, and the causes of the ultimate failure of the venture — bankruptcy and system de-orbit. The paper will address technical, business, and policy issues. The intent of the paper is to provide a balanced and accurate overview of the Iridium experience, to aid future decision-making by policy makers, the business community, and technical experts. Key topics will include the history of the program, the objectives and decision-making of Motorola, the market research and analysis conducted, partnering strategies and their impact, consumer equipment availability, and technical issues — target performance, performance achieved, technical accomplishments, and expected and unexpected technical challenges. The paper will use as sources trade media and business articles on the Iridium program, technical papers and conference presentations, Wall Street analyst's reports, and, where possible, interviews with participants and close observers.

  7. The National Shipbuilding Research Program. Proceedings of the REAPS Technical Symposium. Paper No. 20: Application of the GIFTS-5 Minibased Graphics System for Ship Design and Analysis

    DTIC Science & Technology

    1979-09-01

    Proceedings of the REAPS Technical Symposium Paper No. 20: Application of the GIFTS -5 Minibased Graphics System for Ship Design and Analysis U.S...The National Shipbuilding Research Program Proceedings of the REAPS Technical Symposium Paper No. 20: Application of the GIFTS -5 Minibased Graphics...MERCHANTABILITY AND/OR FITNESS FOR PURPOSE ARE SPECIFICALLY DISCLAIMED. APPLICATION OF THE GIFTS -5 MINIBASED GRAPHICS SYSTEM FOR SHIP DESIGN AND ANALYSIS Dr

  8. The Office of Environmental Management technical reports: a bibliography

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    1997-07-01

    The Office of Environmental Management`s (EM) technical reports bibliography is an annual publication that contains information on scientific and technical reports sponsored by the Office of Environmental Management added to the Energy Science and Technology Database from July 1, 1995 through Sept. 30, 1996. This information is divided into the following categories: Focus Areas and Crosscutting Programs. Support Programs, Technology Integration and International Technology Exchange are now included in the General category. EM`s Office of Science and Technology sponsors this bibliography.

  9. Technical writing practically unified through industry

    NASA Technical Reports Server (NTRS)

    Houston, L. S.

    1981-01-01

    General background details in the development of a university level technical writing program, based upon the writing tasks of the student's occupations, are summarized. Objectives and methods for unifying the courses of study with the needs of industry are discussed. Four academic course divisions, Industries Technologies, in which preparation and training are offered are: Animal, Horticulture, Agriculture, and Agricultural Business. Occupational competence is cited as the main goal for these programs in which technical writing is to be practically unified through industry. Course descriptions are also provided.

  10. A Phenomenological Study Examining the Experiences of High School Graduates Who Participated in a Career and Technical Education Program of Study

    ERIC Educational Resources Information Center

    Goins, Camille Locklear

    2015-01-01

    Career and Technical Education (CTE) programs are designed to help prepare students to become effective workers by equipping them with college and career readiness skills needed for the 21st century workplace. Students who participate in a CTE Program of Study (POS) have the potential for greater success during and after high school because they…

  11. American Chemical Society. 23rd Great Lakes Regional Meeting. Program and abstracts

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1990-01-01

    The technical program includes some 250 papers in 38 sessions, featuring 16 symposia with 99 invited speakers. Program highlights include a plenary lecture, The Origin and Consequences of Scientific Illiteracy, by Jon D. Miller. Sessions for general technical papers are scheduled in the following categories: analytical chemistry; biochemistry; inorganic chemistry; organic chemistry; and physical chemistry. Papers have been processed for inclusion on the data base.

  12. Models for Strategic Program Development. Proceedings of the Annual Meeting of the Council for Programs in Technical and Scientific Communication (27th, Menomonie, Wisconsin, October 19-21, 2000).

    ERIC Educational Resources Information Center

    Maylath, Bruce, Ed.

    This document presents 48 papers delivered at the 2000 annual meeting of the Council for Programs in Technical and Scientific Communication (CPTSC). Papers in the proceedings are divided into 14 subsections: (1) Keynote Presentation: "Global Classroom Project (T. K. Herrington); (2) Opening Session Address: "What Industry Looks for in…

  13. 1983-84 Evaluation Report of Vocational and Technical Education in South Carolina.

    ERIC Educational Resources Information Center

    South Carolina State Advisory Council on Vocational and Technical Education, Columbia.

    This evaluation report contains a series of articles on vocational and technical education encompassing the 1983-84 school year. The articles, collectively, are intended to give an overall picture of vocational and technical education programs in South Carolina. The lead article on technical education strongly urges several changes to bring about…

  14. 7 CFR Exhibit A to Subpart I of... - Self-Help Technical Assistance Grant Agreement

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 13 2011-01-01 2009-01-01 true Self-Help Technical Assistance Grant Agreement A... AGENCY, DEPARTMENT OF AGRICULTURE (CONTINUED) PROGRAM REGULATIONS (CONTINUED) HOUSING Self-Help Technical Assistance Grants Pt. 1944, Subpt. I, Exh. A Exhibit A to Subpart I of Part 1944—Self-Help Technical...

  15. 30 CFR 777.13 - Reporting of technical data.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... descriptions of the methodology used to collect and analyze the data. (b) Technical analyses shall be planned... 30 Mineral Resources 3 2010-07-01 2010-07-01 false Reporting of technical data. 777.13 Section 777... PROGRAMS GENERAL CONTENT REQUIREMENTS FOR PERMIT APPLICATIONS § 777.13 Reporting of technical data. (a) All...

  16. 7 CFR 636.18 - Technical services provided by qualified personnel not affiliated with USDA.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 6 2010-01-01 2010-01-01 false Technical services provided by qualified personnel not... HABITAT INCENTIVES PROGRAM § 636.18 Technical services provided by qualified personnel not affiliated with USDA. (a) NRCS may use the services of qualified TSPs in performing its responsibilities for technical...

  17. Predicting Influential Factors of Secondary Career and Technical Education Teachers' Intent to Stay in the Profession

    ERIC Educational Resources Information Center

    Dainty, Julie D.

    2012-01-01

    Retaining highly qualified career and technical education teachers is important in maintaining and growing quality secondary career and technical education programs. Therefore, the purpose of this study was to identify factors contributing to teacher retention specifically in the area of career and technical education (CTE) and determine…

  18. 10 CFR 455.123 - Grantee records and reports for State grants for administrative expenses, technical assistance...

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ....123 Grantee records and reports for State grants for administrative expenses, technical assistance... institutions participating in the technical assistance phase of this program and upon the energy use reports... to time request. (c) Each copy of any report covering grants for State administrative, technical...

  19. 10 CFR 455.123 - Grantee records and reports for State grants for administrative expenses, technical assistance...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ....123 Grantee records and reports for State grants for administrative expenses, technical assistance... institutions participating in the technical assistance phase of this program and upon the energy use reports... to time request. (c) Each copy of any report covering grants for State administrative, technical...

  20. 10 CFR 455.123 - Grantee records and reports for State grants for administrative expenses, technical assistance...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ....123 Grantee records and reports for State grants for administrative expenses, technical assistance... institutions participating in the technical assistance phase of this program and upon the energy use reports... to time request. (c) Each copy of any report covering grants for State administrative, technical...

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