Sample records for program h10-041 contract

  1. Enterprise Systems Value-Based R&D Portfolio Analytics: Methods, Processes, and Tools

    DTIC Science & Technology

    2014-01-14

    Enterprise Systems Value-Based R&D Portfolio Analytics: Methods, Processes, and Tools Final Technical Report SERC -2014-TR-041-1 January 14...by the U.S. Department of Defense through the Systems Engineering Research Center ( SERC ) under Contract H98230-08-D-0171 (Task Order 0026, RT 51... SERC is a federally funded University Affiliated Research Center managed by Stevens Institute of Technology Any opinions, findings and

  2. 42 CFR 52h.10 - What matters must be reviewed for solicited contract proposals?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false What matters must be reviewed for solicited contract proposals? 52h.10 Section 52h.10 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND... CONTRACT PROJECTS § 52h.10 What matters must be reviewed for solicited contract proposals? (a) Subject to...

  3. A randomized clinical trial comparing pelvic floor muscle training to a Pilates exercise program for improving pelvic muscle strength.

    PubMed

    Culligan, Patrick J; Scherer, Janet; Dyer, Keisha; Priestley, Jennifer L; Guingon-White, Geri; Delvecchio, Donna; Vangeli, Margi

    2010-04-01

    The purpose of this study is to determine whether a Pilates exercise program and a pelvic floor muscle-training (PFMT) program could provide similar improvements in pelvic muscle strength. Sixty-two women with little or no pelvic floor dysfunction were randomized to Pilates or PFMT. Each group had 24 biweekly 1-h sessions with either a physical therapist or Pilates instructor. Strength was measured via perineometry (cmH(2)O). Two questionnaires--pelvic floor distress inventory (PFDI-20) and pelvic floor impact questionnaire (PFIQ-7)--were also collected. At baseline, the Pilates and PFMT groups measured 14.9 +/- 12.5 and 12.5 +/- 10.4 cmH(2)O, respectively (p = 0.41). Both the Pilates and PFMT groups got stronger (6.2 +/- 7.5 cmH(2)O, p = 0.0002 and 6.6 +/- 7.4 cmH(2)O, p = 0.0002, respectively), with no difference between groups p = 0.85. PFIQ and PFDI scores improved from baseline but not between groups. Further study is required to determine if Pilates can actually treat pelvic floor dysfunction.

  4. 77 FR 26815 - Motor Carrier Safety Advisory Committee (MCSAC): Public Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-07

    ...--005; H-08-013; H-09-019--020; and H-09-037--041. Long-Haul Cross Border Trucking Pilot Program Task... Metro station. Copies of all MCSAC Task Statements and an agenda for the entire meeting will be made... Transportation Safety Board (NTSB) At this meeting, the MCSAC will hear presentations and deliberate on Task 12...

  5. Prime Contract Awards, Fiscal Year 1984.

    DTIC Science & Technology

    1984-01-01

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  6. 48 CFR 1815.7001 - NASA Ombudsman Program.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 6 2013-10-01 2013-10-01 false NASA Ombudsman Program... ADMINISTRATION CONTRACTING METHODS AND CONTRACT TYPES CONTRACTING BY NEGOTIATION Ombudsman 1815.7001 NASA Ombudsman Program. NASA's implementation of an ombudsman program is in NPR 5101.33, Procurement Advocacy...

  7. 48 CFR 1815.7001 - NASA Ombudsman Program.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 6 2014-10-01 2014-10-01 false NASA Ombudsman Program... ADMINISTRATION CONTRACTING METHODS AND CONTRACT TYPES CONTRACTING BY NEGOTIATION Ombudsman 1815.7001 NASA Ombudsman Program. NASA's implementation of an ombudsman program is in NPR 5101.33, Procurement Advocacy...

  8. 48 CFR 1815.7001 - NASA Ombudsman Program.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 6 2011-10-01 2011-10-01 false NASA Ombudsman Program... ADMINISTRATION CONTRACTING METHODS AND CONTRACT TYPES CONTRACTING BY NEGOTIATION Ombudsman 1815.7001 NASA Ombudsman Program. NASA's implementation of an ombudsman program is in NPR 5101.33, Procurement Advocacy...

  9. 48 CFR 1815.7001 - NASA Ombudsman Program.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 6 2012-10-01 2012-10-01 false NASA Ombudsman Program... ADMINISTRATION CONTRACTING METHODS AND CONTRACT TYPES CONTRACTING BY NEGOTIATION Ombudsman 1815.7001 NASA Ombudsman Program. NASA's implementation of an ombudsman program is in NPR 5101.33, Procurement Advocacy...

  10. 48 CFR 1815.7001 - NASA Ombudsman Program.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true NASA Ombudsman Program... ADMINISTRATION CONTRACTING METHODS AND CONTRACT TYPES CONTRACTING BY NEGOTIATION Ombudsman 1815.7001 NASA Ombudsman Program. NASA's implementation of an ombudsman program is in NPR 5101.33, Procurement Advocacy...

  11. The Effects of Two Different Stretching Programs on Balance Control and Motor Neuron Excitability

    ERIC Educational Resources Information Center

    Kaya, Fatih; Biçer, Bilal; Yüktasir, Bekir; Willems, Mark E. T.; Yildiz, Nebil

    2018-01-01

    We examined the effects of training (4d/wk for 6 wks) with static stretching (SS) or contract-relax proprioceptive neuromuscular facilitation (PNF) on static balance time and motor neuron excitability. Static balance time, H[subscript max]/M[subscript max] ratios and H-reflex recovery curves (HRRC) were measured in 28 healthy subjects (SS: n = 10,…

  12. Effect of intermittent eccentric contractions on symptoms of muscle microinjury.

    PubMed

    Teague, B N; Schwane, J A

    1995-10-01

    The purpose was to determine whether varying the duration of rest between contractions affects selected symptoms of eccentric contraction-induced skeletal muscle microinjury. Thirty-three women were assigned to three groups (N = 11). Each performed one bout of exercise with each arm involving 10 eccentric contractions of the elbow flexor muscles, lowering a load equaling 60% of maximal static force. One arm exercised continuously; the other exercised with rest periods of 15 s, 5 min, or 10 min between contractions, depending on the group. Preexercise and 0, 24, and 48 h postexercise, symptoms of microinjury in the elbow flexor muscles were assessed: soreness and changes in strength, resting elbow angle ("musculotendinous stiffness"), and arm girth ("swelling"). For all groups combined, 10 continuous contractions caused changes (P < 0.05) in all variables at every measurement time. For example, soreness ratings (0-10 scale) were 4.3 +/- 2.0 (24 h) and 4.3 +/- 2.1 (48 h) and strength was reduced 18% 0 h postexercise. Responses were similar with 15 s of rest between contractions. Although they were moderated, symptoms occurred even with 5 and 10 min of rest. With 10 min between contractions, soreness occurred (e.g., 2.4 +/- 1.5 [24 h]) and strength was 17% reduced 0 h postexercise. Results are most consistent with a mechanical cause of eccentric contraction-induced muscle microinjury, rather than a metabolic or other factor with a short recovery time, although involvement of the latter cannot be ruled out.

  13. Growth of congruently melting Ca0.59Sr0.41F2 crystals and study of their properties

    NASA Astrophysics Data System (ADS)

    Karimov, D. N.; Komar'kova, O. N.; Sorokin, N. I.; Bezhanov, V. A.; Chernov, S. P.; Popov, P. A.; Sobolev, B. P.

    2010-05-01

    Homogeneous crystals of Ca0.59Sr0.41F2 alloy (sp. gr., Fm bar 3 m, a = 0.56057 nm), corresponding to the point of minimum in the melting curve in the CaF2-SrF2 phase diagram, have been grown by the vertical Bridgman method. The optical, mechanical, electrical, and thermophysical properties of Ca0.59Sr0.41F2 and MF2 crystals ( M = Ca, Sr) have been studied and comparatively analyzed. Ca0.59Sr0.41F2 crystals are transparent in the range of 0.133-11.5 μm, have refractive index n D = 1.436, microhardness H μ = 2.63 ± 0.10 GPa, ion conductivity σ = 5 × 10-5 S/cm at 825 K, and thermal conductivity k = 4.0 W m-1 K-1 at 300 K. It is shown that the optical properties of Ca0.59Sr0.41F2 crystals are intermediate between those of CaF2 and SrF2, whereas their mechanical and electrical characteristics are better than the latter compounds.

  14. 42 CFR 52h.9 - What matters must be reviewed for unsolicited contract proposals?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false What matters must be reviewed for unsolicited contract proposals? 52h.9 Section 52h.9 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN... PROJECTS § 52h.9 What matters must be reviewed for unsolicited contract proposals? (a) Except as otherwise...

  15. The effect of compound 48/80 on contractions induced by toluene diisocyanate in isolated guinea-pig bronchus.

    PubMed

    Mapp, C E; Boniotti, A; Papi, A; Chitano, P; Coser, E; Di Stefano, A; Saetta, M; Ciaccia, A; Fabbri, L M

    1993-06-01

    We have investigated the ability of compound 48/80 and of histamine H1 and H2 receptor antagonists to inhibit toluene diisocyanate-induced contractions in isolated guinea-pig bronchi. Compound 48/80 (100 micrograms/ml) significantly inhibited toluene diisocyanate-induced contractions. By contrast, the two histamine H1 and H2 receptor antagonists, chlorpheniramine (10 microM) and cimetidine, (10 microM) did not affect toluene diisocyanate-induced contractions, but significantly inhibited contractions induced by exogenously applied histamine (100 microM) and by 48/80. We investigated which mechanisms 48/80 used to inhibit toluene diisocyanate-induced contractions, paying particular attention to the possible involvement of capsaicin-sensitive primary afferents. In vitro capsaicin desensitization (10 microM for 30 min followed by washing) significantly reduced compound 48/80-induced contractions. A capsaicin-resistant component of contraction was also evident. Ruthenium red (3 microM), an inorganic dye which acts as a selective functional antagonist of capsaicin, did not affect 48/80-induced contraction. MEN 10,207 (Tyr5,D-Trp6,8,9,Arg10)-neurokinin A (4-10) (3 microM) a selective antagonist of NK2-tachykinin receptors significantly reduced 48/80-induced contractions. These results show that compound 48/80 inhibits toluene diisocyanate-induced contractions in isolated guinea-pig bronchi. It is likely that two mechanisms are involved in the inhibition: (1) the release of mediators other than histamine by mast cells, (2) an effect of 48/80 on sensory nerves.

  16. 48 CFR 552.216-71 - Economic Price Adjustment-Special Order Program Contracts.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Economic Price Adjustment... Provisions and Clauses 552.216-71 Economic Price Adjustment—Special Order Program Contracts. As prescribed in 516.203-4(a), insert the following clause: Economic Price Adjustment—Special Order Program Contracts...

  17. 48 CFR 552.216-71 - Economic Price Adjustment-Special Order Program Contracts.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 4 2011-10-01 2011-10-01 false Economic Price Adjustment... Provisions and Clauses 552.216-71 Economic Price Adjustment—Special Order Program Contracts. As prescribed in 516.203-4(a), insert the following clause: Economic Price Adjustment—Special Order Program Contracts...

  18. 48 CFR 552.216-71 - Economic Price Adjustment-Special Order Program Contracts.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 4 2014-10-01 2014-10-01 false Economic Price Adjustment... Provisions and Clauses 552.216-71 Economic Price Adjustment—Special Order Program Contracts. As prescribed in 516.203-4(a), insert the following clause: Economic Price Adjustment—Special Order Program Contracts...

  19. 48 CFR 552.216-71 - Economic Price Adjustment-Special Order Program Contracts.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 4 2013-10-01 2013-10-01 false Economic Price Adjustment... Provisions and Clauses 552.216-71 Economic Price Adjustment—Special Order Program Contracts. As prescribed in 516.203-4(a), insert the following clause: Economic Price Adjustment—Special Order Program Contracts...

  20. 48 CFR 552.216-71 - Economic Price Adjustment-Special Order Program Contracts.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 4 2012-10-01 2012-10-01 false Economic Price Adjustment... Provisions and Clauses 552.216-71 Economic Price Adjustment—Special Order Program Contracts. As prescribed in 516.203-4(a), insert the following clause: Economic Price Adjustment—Special Order Program Contracts...

  1. A retrospective study on anthropometrical, physical fitness, and motor coordination characteristics that influence dropout, contract status, and first-team playing time in high-level soccer players aged eight to eighteen years.

    PubMed

    Deprez, Dieter N; Fransen, Job; Lenoir, Matthieu; Philippaerts, Renaat M; Vaeyens, Roel

    2015-06-01

    The goal of this article was twofold, and a 2-study approach was conducted. The first study aimed to expose the anthropometrical, physical performance, and motor coordination characteristics that influence dropout from a high-level soccer training program in players aged 8-16 years. The mixed-longitudinal sample included 388 Belgian youth soccer players who were assigned to either a "club group" or a "dropout group." In the second study, cross-sectional data of anthropometry, physical performance, and motor coordination were retrospectively explored to investigate which characteristics influence future contract status (contract vs. no contract group) and first-team playing time for 72 high-level youth soccer players (mean age = 16.2 years). Generally, club players outperformed their dropout peers for motor coordination, soccer-specific aerobic endurance, and speed. Anthropometry and estimated maturity status did not discriminate between club and dropout players. Contract players jumped further (p = 0.011) and had faster times for a 5-m sprint (p = 0.041) than no contract players. The following prediction equation explains 16.7% of the variance in future playing minutes in adolescent youth male soccer players: -2,869.3 + 14.6 × standing broad jump. Practitioners should include the evaluation of motor coordination, aerobic endurance, and speed performances to distinguish high-level soccer players further succeeding a talent development program and future dropout players, between 8 and 16 years. From the age of 16 years, measures of explosivity are supportive when selecting players into a future professional soccer career.

  2. Detection of Neutral Phosphorus in the Near-ultraviolet Spectra of Late-type Stars

    NASA Astrophysics Data System (ADS)

    Roederer, Ian U.; Jacobson, Heather R.; Thanathibodee, Thanawuth; Frebel, Anna; Toller, Elizabeth

    2014-12-01

    We report the detection of several absorption lines of neutral phosphorus (P, Z = 15) in archival near-ultraviolet spectra obtained with the Space Telescope Imaging Spectrograph on board the Hubble Space Telescope. We derive phosphorus abundances or interesting upper limits in 14 late-type stars with metallicities spanning -3.8 < [Fe/H] <-0.1. Previously, phosphorus had only been studied in Galactic stars with -1.0 < [Fe/H] <+0.3. Iron lines reveal abundance offsets between the optical and ultraviolet regions, and we discuss and apply a correction factor to account for this offset. In stars with [Fe/H] >-1.0, the [P/Fe] ratio decreases toward the solar value with increasing metallicity, in agreement with previous observational studies. In stars with [Fe/H] <-1.0, lang[P/Fe]rang = +0.04 ± 0.10, which overlaps with the [P/Fe] ratios found in several high-redshift damped Lyman-α systems. This behavior hints at a primary origin in massive stars. Based on observations made with the NASA/ESA Hubble Space Telescope, obtained at the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS 5-26555. This work is supported through program AR-13246 and is based on observations associated with programs GO-7348, GO-7433, GO-8197, GO-9048, GO-9049, GO-9455, GO-9804, GO-12268, GO-12554, and GO-12976. Portions of this work are based on data obtained from the European Southern Observatory (ESO) Science Archive Facility. These data are associated with Programs 065.L-0507(A), 067.D-0439(A), 072.B-0179(A), 074.C-0364(A), 076.B-0055(A), and 266.D-5655(A). Portions of this research have also made use of the Keck Observatory Archive (KOA), which is operated by the W.M. Keck Observatory and the NASA Exoplanet Science Institute (NExScI), under contract with the National Aeronautics and Space Administration. These data are associated with Programs H2aH (P.I: Boesgaard), H5aH (P.I: Stephens), and H47aH (P.I: Boesgaard). Other portions of this work are based on data gathered with the 6.5 m Magellan Telescopes located at Las Campanas Observatory, Chile, and the McDonald Observatory of The University of Texas at Austin.

  3. 32 CFR 169a.10 - Contracts.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 1 2010-07-01 2010-07-01 false Contracts. 169a.10 Section 169a.10 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE DEFENSE CONTRACTING COMMERCIAL ACTIVITIES PROGRAM PROCEDURES Procedures § 169a.10 Contracts. When contract cost becomes unreasonable or performance...

  4. 32 CFR 169a.10 - Contracts.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 1 2013-07-01 2013-07-01 false Contracts. 169a.10 Section 169a.10 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE DEFENSE CONTRACTING COMMERCIAL ACTIVITIES PROGRAM PROCEDURES Procedures § 169a.10 Contracts. When contract cost becomes unreasonable or performance...

  5. 32 CFR 169a.10 - Contracts.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 1 2011-07-01 2011-07-01 false Contracts. 169a.10 Section 169a.10 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE DEFENSE CONTRACTING COMMERCIAL ACTIVITIES PROGRAM PROCEDURES Procedures § 169a.10 Contracts. When contract cost becomes unreasonable or performance...

  6. Blood pressure and plasma catecholamine responses to various challenges during exercise-recovery in man.

    PubMed

    Péronnet, F; Massicotte, D; Paquet, J E; Brisson, G; de Champlain, J

    1989-01-01

    The purpose of this study was to assess the effects of a 2 h cycle exercise (50% VO2max) on heart rate (HR) and blood pressure (BP), and on plasma epinephrine (E) and norepinephrine (NE) concentrations, during the recovery period in seven normotensive subjects. Measurements were made at rest in supine (20 min) and standing (10 min) positions, during isometric exercise (hand-grip, 3 min, 25% maximal voluntary, contraction), in response to a mild psychosocial challenge (Stroop conflicting color word task) and during a 5-min period of light exercise (42 +/- 3% VO2max). Data were compared to measurements taken on another occasion under similar experimental conditions, without a previous exercise bout (control). The results showed HR to be slightly elevated in all conditions following the exercise bout. However, diastolic and systolic BP during the recovery period following exercise were not significantly different from the values observed in the control situation. Plasma NE concentrations in supine position and in response to the various physiological and/or psychosocial challenges were similar in the control situation and during the recovery period following exercise. On the other hand plasma E (nmol.1-1) was about 50% lower at rest (0.11 +/- 0.03 vs 0.23 +/- 0.04) as well as in response to hand-grip (0.21 +/- 0.04 vs 0.41 +/- 0.20) and the Stroop-test (0.21 +/- 0.05 vs 0.41 +/- 0.15) following the exercise bout.(ABSTRACT TRUNCATED AT 250 WORDS)

  7. Probiotic (VSL#3) for Gulf War Illness

    DTIC Science & Technology

    2012-10-01

    W81XWH-10-1-0593 TITLE: Probiotic (VSL#3) for Gulf War Illness. PRINCIPAL INVESTIGATOR: Ashok Tuteja, M.D. M.P.H...SUBTITLE 5a. CONTRACT NUMBER Probiotic (VSL#3) for Gulf War Illness 5b. GRANT NUMBER W81XWH-10-1-0593 5c. PROGRAM ELEMENT NUMBER...unable to get IND (Investigational New Drug) number for the probiotic , Bifidobacterium infantis 35624 (Align®). We requested the Department of Defense

  8. 48 CFR 970.2305 - Workplace substance abuse programs-management and operating contracts.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 5 2014-10-01 2014-10-01 false Workplace substance abuse programs-management and operating contracts. 970.2305 Section 970.2305 Federal Acquisition Regulations... Work Place 970.2305 Workplace substance abuse programs—management and operating contracts. ...

  9. 48 CFR 970.2305 - Workplace substance abuse programs-management and operating contracts.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 5 2012-10-01 2012-10-01 false Workplace substance abuse programs-management and operating contracts. 970.2305 Section 970.2305 Federal Acquisition Regulations... Work Place 970.2305 Workplace substance abuse programs—management and operating contracts. ...

  10. 48 CFR 970.2305 - Workplace substance abuse programs-management and operating contracts.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 5 2013-10-01 2013-10-01 false Workplace substance abuse programs-management and operating contracts. 970.2305 Section 970.2305 Federal Acquisition Regulations... Work Place 970.2305 Workplace substance abuse programs—management and operating contracts. ...

  11. 48 CFR 970.2305 - Workplace substance abuse programs-management and operating contracts.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Workplace substance abuse programs-management and operating contracts. 970.2305 Section 970.2305 Federal Acquisition Regulations... Work Place 970.2305 Workplace substance abuse programs—management and operating contracts. ...

  12. Summary of Results, Chief Joseph Dam Cultural Resources Project, Washington.

    DTIC Science & Technology

    1985-01-01

    Cmpbll, . R S*CONTRACT OR GRANT NUMUER(a) S. ambeled. with V.CazoR Dalai" P. Davis, D. Hibbert, S. Key, L.L. and L.A. Leeds, DACW67-78-C-0106 -: E ...Leopold, E . Lohse, S. Livingston, C. Miss, R. Nickmann. L. Salo, 0. Sammons-Lohse, (cont.) ~.s SPERFORMING ORGANIZATION NAME AND0 ADDRESS 10...Dat Eneed V 7 •,- "Mop-, e ~~l 𔄁 . - , ., - . W~PY OF REStALTS. 041 EF JOSEPH DAN CUtlJRAL RESOURCES PROECT, WASHINGTON edited by Sarah K. Campbell

  13. 41 CFR 51-10.150 - Program accessibility: Existing facilities.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true Program accessibility: Existing facilities. 51-10.150 Section 51-10.150 Public Contracts and Property Management Other Provisions... result in a fundamental alteration in the nature of a program or activity or in undue financial and...

  14. 48 CFR 926.7104 - Contract clause.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 5 2012-10-01 2012-10-01 false Contract clause. 926.7104 Section 926.7104 Federal Acquisition Regulations System DEPARTMENT OF ENERGY SOCIOECONOMIC PROGRAMS OTHER SOCIOECONOMIC PROGRAMS Implementation of Section 3161 of the National Defense Authorization Act for Fiscal Year 1993. 926.7104 Contract clause....

  15. 48 CFR 926.7104 - Contract clause.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Contract clause. 926.7104 Section 926.7104 Federal Acquisition Regulations System DEPARTMENT OF ENERGY SOCIOECONOMIC PROGRAMS OTHER SOCIOECONOMIC PROGRAMS Implementation of Section 3161 of the National Defense Authorization Act for Fiscal Year 1993. 926.7104 Contract clause....

  16. 48 CFR 926.7104 - Contract clause.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Contract clause. 926.7104 Section 926.7104 Federal Acquisition Regulations System DEPARTMENT OF ENERGY SOCIOECONOMIC PROGRAMS OTHER SOCIOECONOMIC PROGRAMS Implementation of Section 3161 of the National Defense Authorization Act for Fiscal Year 1993. 926.7104 Contract clause....

  17. 48 CFR 926.7104 - Contract clause.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 5 2014-10-01 2014-10-01 false Contract clause. 926.7104 Section 926.7104 Federal Acquisition Regulations System DEPARTMENT OF ENERGY SOCIOECONOMIC PROGRAMS OTHER SOCIOECONOMIC PROGRAMS Implementation of Section 3161 of the National Defense Authorization Act for Fiscal Year 1993. 926.7104 Contract clause....

  18. 48 CFR 926.7104 - Contract clause.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 5 2013-10-01 2013-10-01 false Contract clause. 926.7104 Section 926.7104 Federal Acquisition Regulations System DEPARTMENT OF ENERGY SOCIOECONOMIC PROGRAMS OTHER SOCIOECONOMIC PROGRAMS Implementation of Section 3161 of the National Defense Authorization Act for Fiscal Year 1993. 926.7104 Contract clause....

  19. An Updated Statistical Search for Super-Metal-Rich Stars of Types F, G, and K

    NASA Astrophysics Data System (ADS)

    Taylor, B. J.

    2001-05-01

    Results are reported for an updated version of a published statistical search for super-metal-rich (SMR) stars (Taylor 1996, ApJS 102, 105). By definition, [Fe/H] > +0.2 dex is required for such stars, with false-alarm probabilities p < 0.05. The search is based on two catalogs of homogenized high-dispersion values of [Fe/H] drawn from diverse literature sources. For dwarfs, an updated version of the Taylor (1995, PASP 107, 734) catalog is consulted. For evolved stars, the Taylor (1999, A&AS 143, 523) catalog is searched. A preliminary list of SMR subgiants and dwarfs is unchanged from 1996: ρ 1 Cnc: [Fe/H] = +0.41 +/- 0.046 dex (p = 7 x 10-4). HD 112164: [Fe/H] = +0.36 +/- 0.052 dex (p = 4 x 10-3). η Boo: [Fe/H] = +0.32 +/- 0.029 dex (p = 2 x 10-4). 14 Her: [Fe/H] = +0.39 +/- 0.046 dex (p = 2 x 10-4). μ Ara: [Fe/H] = +0.38 +/- 0.046 dex (p = 4 x 10-3). 31 Aql: [Fe/H] = +0.37 +/- 0.035 dex (p = 2 x 10-5). δ Pav: [Fe/H] = +0.41 +/- 0.046 dex (p = 7 x 10-4). The product of the stated values of p is 9 x 10-21. This is the formal probability that none of the stars are actually SMR. As in 1996, no statistically defensible examples of SMR giants are found. Mu Leo is not an exception to this statement (Taylor 1999, A&AS 344, 655; Taylor 2000, BAAS 32, 1472). The lack of known SMR giants may be due to neglect of promising candidates (listed, for example, by Deming & Butler 1979, AJ 84, 839). For this reason, the existence or nonexistence of SMR giants continues to be an open question. This research has been supported by the BYU College of Physical and Mathematical Sciences.

  20. Plasticity of non-adrenergic non-cholinergic bladder contractions in rats after chronic spinal cord injury

    PubMed Central

    Lai, H. Henry; Munoz, Alvaro; Smith, Christopher P.; Boone, Timothy B.; Somogyi, George T.

    2011-01-01

    The purpose of this study was to examine the pharmacologic plasticity of cholinergic, non-adrenergic non-cholinergic (NANC), and purinergic contractions in neurogenic bladder strips from spinal cord injured (SCI) rats. Bladder strips were harvested from female rats three to four weeks after T9–T10 spinal cord transection. The strips were electrically stimulated using two experimental protocols to compare the contribution of muscarinic and NANC/purinergic contractions in the presence and the absence of carbachol or muscarine. The endpoints of the study were: (1) percent NANC contraction that was unmasked by the muscarinic antagonist 4-DAMP, and (2) P2X purinergic contraction that was evoked by α,β–methylene ATP. NANC contraction accounted for 78.5% of the neurally evoked contraction in SCI bladders. When SCI bladder strips were treated with carbachol (10 µM) prior to 4-DAMP (500 nM), the percent NANC contraction decreased dramatically to only 13.1% of the neurally evoked contraction (p=0.041). This was accompanied by a substantial decrease in α,β–methylene ATP evoked P2X contraction, and desensitization of purinergic receptors (the ratio of subsequent over initial P2X contraction decreased from 97.2% to 42.1%, p=0.0017). Sequential activation of the cholinergic receptors with carbachol (or with muscarine in neurally intact bladders) and unmasking of the NANC response with 4-DAMP switched the neurally evoked bladder contraction from predominantly NANC to predominantly cholinergic. We conclude that activation of muscarinic receptors (with carbachol or muscarine) blocks NANC and purinergic contractions in neurally intact or in SCI rat bladders. The carbachol-induced inhibition of the NANC contraction is expressed more in SCI bladders compared to neurally intact bladders. Along with receptor plasticity, this change in bladder function may involve P2X-independent mechanisms. PMID:21689735

  1. All Prime Contract Awards by State or Country, Place, and Contractor, FY 87. Part 14. Adelphia, New Jersey-White Sands Missile Range, New Mexico.

    DTIC Science & Technology

    1987-01-01

    N N N N N N N4 03100 9 0) 0 N000.J Nc 0 N0. N- 0 0... 0 N 0 0 cacao 010 0 00041 0 00-1 04 0 04- 0 041 0 0 i101001 0 0 0001- 0 004C 01- 0 01- 0 01- 0 0...hJ0000th 00 (I 0000000 9L I A004 I .4-4-el *-40 L) I in0 *.-44.4-eco L4.- " -0 M -eem-m4-e-4e-4- De ) ma~ *40) 0 *.m4 N 0001 CL 40 100 000O 0-00-0-0 x04...1-. Ln 4) 01 q 4 N de I l -*I 01 &1 ago 01 0 402 0 0 too1 up 4 4A ~ OA >. II U0 Z9 1’ 1 1o 0 0 30~~~ ~q 010. N 0. 1 (14- 1 (( 04 41N 01( 0 01( 3.4 0m

  2. 48 CFR 2146.270 - FEGLI Program quality assurance requirements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... MANAGEMENT, FEDERAL EMPLOYEES GROUP LIFE INSURANCE FEDERAL ACQUISITION REGULATION CONTRACT MANAGEMENT QUALITY ASSURANCE Contract Quality Requirements 2146.270 FEGLI Program quality assurance requirements. (a) The... 48 Federal Acquisition Regulations System 6 2013-10-01 2013-10-01 false FEGLI Program quality...

  3. 48 CFR 2146.270 - FEGLI Program quality assurance requirements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... MANAGEMENT, FEDERAL EMPLOYEES GROUP LIFE INSURANCE FEDERAL ACQUISITION REGULATION CONTRACT MANAGEMENT QUALITY ASSURANCE Contract Quality Requirements 2146.270 FEGLI Program quality assurance requirements. (a) The... 48 Federal Acquisition Regulations System 6 2014-10-01 2014-10-01 false FEGLI Program quality...

  4. 48 CFR 2146.270 - FEGLI Program quality assurance requirements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... MANAGEMENT, FEDERAL EMPLOYEES GROUP LIFE INSURANCE FEDERAL ACQUISITION REGULATION CONTRACT MANAGEMENT QUALITY ASSURANCE Contract Quality Requirements 2146.270 FEGLI Program quality assurance requirements. (a) The... 48 Federal Acquisition Regulations System 6 2012-10-01 2012-10-01 false FEGLI Program quality...

  5. 48 CFR 2146.270 - FEGLI Program quality assurance requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... MANAGEMENT, FEDERAL EMPLOYEES GROUP LIFE INSURANCE FEDERAL ACQUISITION REGULATION CONTRACT MANAGEMENT QUALITY ASSURANCE Contract Quality Requirements 2146.270 FEGLI Program quality assurance requirements. (a) The... 48 Federal Acquisition Regulations System 6 2011-10-01 2011-10-01 false FEGLI Program quality...

  6. 48 CFR 2146.270 - FEGLI Program quality assurance requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... MANAGEMENT, FEDERAL EMPLOYEES GROUP LIFE INSURANCE FEDERAL ACQUISITION REGULATION CONTRACT MANAGEMENT QUALITY ASSURANCE Contract Quality Requirements 2146.270 FEGLI Program quality assurance requirements. (a) The... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true FEGLI Program quality...

  7. 48 CFR 822.406-11 - Contract terminations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... SOCIOECONOMIC PROGRAMS APPLICATION OF LABOR LAWS TO GOVERNMENT ACQUISITIONS Labor Standards for Contracts Involving Construction 822.406-11 Contract terminations. (a) Contracting officers must submit any proposed... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Contract terminations. 822...

  8. 42 CFR 421.212 - Railroad Retirement Board contracts.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Railroad Retirement Board contracts. 421.212... SERVICES (CONTINUED) MEDICARE PROGRAM MEDICARE CONTRACTING Carriers § 421.212 Railroad Retirement Board contracts. In accordance with this subpart C, the Railroad Retirement Board contracts with DMEPOS regional...

  9. 10 CFR 850 Implementation of Requirements

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lee, S

    2012-01-05

    10 CFR 850 defines a contractor as any entity, including affiliated entities, such as a parent corporation, under contract with DOE, including a subcontractor at any tier, with responsibility for performing work at a DOE site in furtherance of a DOE mission. The Chronic Beryllium Disease Prevention Program (CBDPP) applies to beryllium-related activities that are performed at the Lawrence Livermore National Laboratory (LLNL). The CBDPP or Beryllium Safety Program is integrated into the LLNL Worker Safety and Health Program and, thus, implementation documents and responsibilities are integrated in various documents and organizational structures. Program development and management of the CBDPPmore » is delegated to the Environment, Safety and Health (ES&H) Directorate, Worker Safety and Health Functional Area. As per 10 CFR 850, Lawrence Livermore National Security, LLC (LLNS) periodically submits a CBDPP to the National Nuclear Security Administration/Livermore Site Office (NNSA/LSO). The requirements of this plan are communicated to LLNS workers through ES&H Manual Document 14.4, 'Working Safely with Beryllium.' 10 CFR 850 is implemented by the LLNL CBDPP, which integrates the safety and health standards required by the regulation, components of the LLNL Integrated Safety Management System (ISMS), and incorporates other components of the LLNL ES&H Program. As described in the regulation, and to fully comply with the regulation, specific portions of existing programs and additional requirements are identified in the CBDPP. The CBDPP is implemented by documents that interface with the workers, principally through ES&H Manual Document 14.4. This document contains information on how the management practices prescribed by the LLNL ISMS are implemented, how beryllium hazards that are associated with LLNL work activities are controlled, and who is responsible for implementing the controls. Adherence to the requirements and processes described in the ES&H Manual ensures that ES&H practices across LLNL are developed in a consistent manner. Other implementing documents, such as the ES&H Manual, are integral in effectively implementing 10 CFR 850.« less

  10. 48 CFR 1519.203 - Mentor-protege.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Mentor-protege. 1519.203... PROGRAMS SMALL BUSINESS PROGRAMS Policies 1519.203 Mentor-protege. (a) The Contracting officer shall insert the clause at 1552.219-70, Mentor-Protege Program, in all contracts under which the Contractor has...

  11. 48 CFR 225.872-5 - Contract administration.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Policy and International Contracting), ((703) 697-9351, DSN 227-9351). (b) Follow the contract... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Contract administration... SYSTEM, DEPARTMENT OF DEFENSE SOCIOECONOMIC PROGRAMS FOREIGN ACQUISITION Other International Agreements...

  12. 48 CFR 225.872-5 - Contract administration.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Policy and International Contracting), ((703) 697-9351, DSN 227-9351). (b) Follow the contract... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Contract administration... SYSTEM, DEPARTMENT OF DEFENSE SOCIOECONOMIC PROGRAMS FOREIGN ACQUISITION Other International Agreements...

  13. 48 CFR 630.201 - Contract requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 4 2011-10-01 2011-10-01 false Contract requirements. 630.201 Section 630.201 Federal Acquisition Regulations System DEPARTMENT OF STATE GENERAL CONTRACTING REQUIREMENTS COST ACCOUNTING STANDARDS ADMINISTRATION CAS Program Requirements 630.201 Contract requirements. ...

  14. 48 CFR 1430.201 - Contract requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Contract requirements. 1430.201 Section 1430.201 Federal Acquisition Regulations System DEPARTMENT OF THE INTERIOR GENERAL CONTRACTING REQUIREMENTS COST ACCOUNTING STANDARDS ADMINISTRATION CAS Program Requirements 1430.201 Contract...

  15. 48 CFR 330.201 - Contract requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 4 2011-10-01 2011-10-01 false Contract requirements. 330.201 Section 330.201 Federal Acquisition Regulations System HEALTH AND HUMAN SERVICES GENERAL CONTRACTING REQUIREMENTS COST ACCOUNTING STANDARDS CAS Program Requirements 330.201 Contract requirements. ...

  16. 48 CFR 430.201 - Contract requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 4 2011-10-01 2011-10-01 false Contract requirements. 430.201 Section 430.201 Federal Acquisition Regulations System DEPARTMENT OF AGRICULTURE GENERAL CONTRACTING REQUIREMENTS COST ACCOUNTING STANDARDS ADMINISTRATION CAS Program Requirements 430.201 Contract...

  17. 48 CFR 30.201 - Contract requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Contract requirements. 30.201 Section 30.201 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION GENERAL CONTRACTING REQUIREMENTS COST ACCOUNTING STANDARDS ADMINISTRATION CAS Program Requirements 30.201 Contract...

  18. 48 CFR 1330.201 - Contract requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Contract requirements. 1330.201 Section 1330.201 Federal Acquisition Regulations System DEPARTMENT OF COMMERCE GENERAL CONTRACTING REQUIREMENTS COST ACCOUNTING STANDARDS ADMINISTRATION CAS Program Requirements 1330.201 Contract...

  19. Tensiometric studies of cytokinesis in cleaving sand dollar eggs.

    PubMed

    Rappaport, R

    1977-09-01

    Tensions exerted by cleavage furrows of Echinarachnius parma were measured by means of calibrated, flexible glass needles. The tensions exerted by the first and second furrows in isometric contraction were, respectively, 1.58 X 10(-3) dyne (S.D. 0.41 X 10(-3) dyne) and 1.43 X 10(-3) dyne (S.D. 0.44 X 10(-3) dyne). The difference between the two means is not significant. The tensions exerted by the same cleavage furrow at two different lengths, of which the shorter was about 66% the length of the longer, were not significantly different. When the progress of a second cleavage furrow was mechanically blocked, it continued to exert maximum tension up to 9 minutes after its companion blastomere, which served as a time control, completed cleavage.

  20. 45 CFR 800.401 - Contract performance.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 3 2014-10-01 2014-10-01 false Contract performance. 800.401 Section 800.401...-STATE PLAN PROGRAM Compliance § 800.401 Contract performance. (a) General. An MSPP issuer must perform... MSPP contract; (7) Applying performance standards for assuring contract quality as outlined at § 800...

  1. 45 CFR 800.401 - Contract performance.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 3 2013-10-01 2013-10-01 false Contract performance. 800.401 Section 800.401...-STATE PLAN PROGRAM Compliance § 800.401 Contract performance. (a) General. An MSPP issuer must perform... MSPP contract; (7) Applying performance standards for assuring contract quality as outlined at § 800...

  2. 48 CFR 235.006-70 - Manufacturing Technology Program.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Manufacturing Technology... CONTRACTING 235.006-70 Manufacturing Technology Program. In accordance with 10 U.S.C. 2521(d), for acquisitions under the Manufacturing Technology Program— (a) Award all contracts using competitive procedures...

  3. 48 CFR 235.006-70 - Manufacturing Technology Program.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Manufacturing Technology... CONTRACTING 235.006-70 Manufacturing Technology Program. In accordance with 10 U.S.C. 2521(d), for acquisitions under the Manufacturing Technology Program— (a) Award all contracts using competitive procedures...

  4. 48 CFR 235.006-70 - Manufacturing Technology Program.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Manufacturing Technology... CONTRACTING 235.006-70 Manufacturing Technology Program. In accordance with 10 U.S.C. 2521(d), for acquisitions under the Manufacturing Technology Program— (a) Award all contracts using competitive procedures...

  5. 48 CFR 235.006-70 - Manufacturing Technology Program.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Manufacturing Technology... CONTRACTING 235.006-70 Manufacturing Technology Program. In accordance with 10 U.S.C. 2521(d), for acquisitions under the Manufacturing Technology Program— (a) Award all contracts using competitive procedures...

  6. 48 CFR 235.006-70 - Manufacturing Technology Program.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Manufacturing Technology... CONTRACTING 235.006-70 Manufacturing Technology Program. In accordance with 10 U.S.C. 2521(d), for acquisitions under the Manufacturing Technology Program— (a) Award all contracts using competitive procedures...

  7. 46 CFR 160.041-3 - Construction and workmanship.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 6 2010-10-01 2010-10-01 false Construction and workmanship. 160.041-3 Section 160.041-3 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Kits, First-Aid, for Merchant Vessels § 160.041...

  8. Probiotic (VSL 3) for Gulf War Illness

    DTIC Science & Technology

    2016-10-01

    Award Number: W81XWH-10-1-0593 TITLE: Probiotic (VSL#3) for Gulf War Illness. PRINCIPAL INVESTIGATOR: Ashok Tuteja, M.D. M.P.H. CONTRACTING...NUMBER Probiotic (VSL#3) for Gulf War Illness. 5b. GRANT NUMBER W81XWH-10-1-0593 5c. PROGRAM ELEMENT NUMBER 6 . AUTHOR(S) 5d. PROJECT NUMBER Ashok...objective of the study is to determine whether probiotic VisbiomeTMwill improve 1) Intestinal symptoms of Irritable Bowel Syndrome and 2) Non

  9. 48 CFR 619.808 - Contract negotiation.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 4 2011-10-01 2011-10-01 false Contract negotiation. 619.808 Section 619.808 Federal Acquisition Regulations System DEPARTMENT OF STATE SOCIOECONOMIC PROGRAMS... Contract negotiation. ...

  10. 48 CFR 619.808 - Contract negotiation.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 4 2012-10-01 2012-10-01 false Contract negotiation. 619.808 Section 619.808 Federal Acquisition Regulations System DEPARTMENT OF STATE SOCIOECONOMIC PROGRAMS... Contract negotiation. ...

  11. 48 CFR 619.808 - Contract negotiation.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 4 2013-10-01 2013-10-01 false Contract negotiation. 619.808 Section 619.808 Federal Acquisition Regulations System DEPARTMENT OF STATE SOCIOECONOMIC PROGRAMS... Contract negotiation. ...

  12. 48 CFR 619.808 - Contract negotiation.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Contract negotiation. 619.808 Section 619.808 Federal Acquisition Regulations System DEPARTMENT OF STATE SOCIOECONOMIC PROGRAMS... Contract negotiation. ...

  13. 48 CFR 619.808 - Contract negotiation.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 4 2014-10-01 2014-10-01 false Contract negotiation. 619.808 Section 619.808 Federal Acquisition Regulations System DEPARTMENT OF STATE SOCIOECONOMIC PROGRAMS... Contract negotiation. ...

  14. 48 CFR 22.610 - Contract clause.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... PROGRAMS APPLICATION OF LABOR LAWS TO GOVERNMENT ACQUISITIONS Walsh-Healey Public Contracts Act 22.610... Contracts Act, in solicitations and contracts covered by the Act (see 22.603, 22.604, and 22.605). [61 FR... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Contract clause. 22.610...

  15. 48 CFR 19.804-2 - Agency offering.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Agency offering. 19.804-2... PROGRAMS SMALL BUSINESS PROGRAMS Contracting With the Small Business Administration (the 8(a) Program) 19... following information applicable to each prospective contract: (1) A description of the work to be performed...

  16. 48 CFR 570.603 - GSAR contract clauses.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false GSAR contract clauses. 570.603 Section 570.603 Federal Acquisition Regulations System GENERAL SERVICES ADMINISTRATION SPECIAL CONTRACTING PROGRAMS ACQUIRING LEASEHOLD INTERESTS IN REAL PROPERTY Solicitation Provisions and Contract...

  17. 48 CFR 1819.7302 - NASA contract clauses.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 6 2013-10-01 2013-10-01 false NASA contract clauses. 1819.7302 Section 1819.7302 Federal Acquisition Regulations System NATIONAL AERONAUTICS AND SPACE... Business Technology Transfer (STTR) Programs 1819.7302 NASA contract clauses. (a) Contracting officers...

  18. 48 CFR 1819.7302 - NASA contract clauses.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true NASA contract clauses. 1819.7302 Section 1819.7302 Federal Acquisition Regulations System NATIONAL AERONAUTICS AND SPACE... Business Technology Transfer (STTR) Programs 1819.7302 NASA contract clauses. (a) Contracting officers...

  19. 48 CFR 1819.7302 - NASA contract clauses.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 6 2012-10-01 2012-10-01 false NASA contract clauses. 1819.7302 Section 1819.7302 Federal Acquisition Regulations System NATIONAL AERONAUTICS AND SPACE... Business Technology Transfer (STTR) Programs 1819.7302 NASA contract clauses. (a) Contracting officers...

  20. 48 CFR 1819.7302 - NASA contract clauses.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 6 2014-10-01 2014-10-01 false NASA contract clauses. 1819.7302 Section 1819.7302 Federal Acquisition Regulations System NATIONAL AERONAUTICS AND SPACE... Business Technology Transfer (STTR) Programs 1819.7302 NASA contract clauses. (a) Contracting officers...

  1. 48 CFR 1819.7302 - NASA contract clauses.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 6 2011-10-01 2011-10-01 false NASA contract clauses. 1819.7302 Section 1819.7302 Federal Acquisition Regulations System NATIONAL AERONAUTICS AND SPACE... Business Technology Transfer (STTR) Programs 1819.7302 NASA contract clauses. (a) Contracting officers...

  2. 46 CFR 160.041-4 - Contents.

    Code of Federal Regulations, 2010 CFR

    1997-10-01

    ... 46 Shipping 6 1997-10-01 1997-10-01 false Contents. 160.041-4 Section 160.041-4 EQUIPMENT... Vessels § 160.041-4 Contents. (a) Individual cartons. Cartons shall be of the standard commercial unit..., size of contents, and method of use, and shall contain all information required by Federal and State...

  3. 47 CFR 0.41 - Functions of the Office.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 1 2010-10-01 2010-10-01 false Functions of the Office. 0.41 Section 0.41 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL COMMISSION ORGANIZATION Organization Office of General Counsel § 0.41 Functions of the Office. The Office of the General Counsel has the following duties and...

  4. 46 CFR 160.041-5 - Inspections and tests.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 6 2010-10-01 2010-10-01 false Inspections and tests. 160.041-5 Section 160.041-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Kits, First-Aid, for Merchant Vessels § 160.041-5 Inspections...

  5. 48 CFR 322.810 - Solicitation provisions and contract clauses.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 4 2011-10-01 2011-10-01 false Solicitation provisions and contract clauses. 322.810 Section 322.810 Federal Acquisition Regulations System HEALTH AND HUMAN... Opportunity 322.810 Solicitation provisions and contract clauses. (h) The Contracting Officer shall insert the...

  6. 48 CFR 322.810 - Solicitation provisions and contract clauses.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Solicitation provisions and contract clauses. 322.810 Section 322.810 Federal Acquisition Regulations System HEALTH AND HUMAN... Opportunity 322.810 Solicitation provisions and contract clauses. (h) The Contracting Officer shall insert the...

  7. 42 CFR 417.408 - Contract application process.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Contract application process. 417.408 Section 417... (CONTINUED) MEDICARE PROGRAM HEALTH MAINTENANCE ORGANIZATIONS, COMPETITIVE MEDICAL PLANS, AND HEALTH CARE PREPAYMENT PLANS Qualifying Conditions for Medicare Contracts § 417.408 Contract application process. (a...

  8. 48 CFR 970.5223-4 - Workplace Substance Abuse Programs at DOE Sites.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 5 2013-10-01 2013-10-01 false Workplace Substance Abuse... and Contract Clauses for Management and Operating Contracts 970.5223-4 Workplace Substance Abuse... 10 CFR part 707, Workplace Substance Abuse Programs at DOE Sites, incorporated herein by reference...

  9. 48 CFR 970.5223-4 - Workplace Substance Abuse Programs at DOE Sites.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Workplace Substance Abuse... and Contract Clauses for Management and Operating Contracts 970.5223-4 Workplace Substance Abuse... 10 CFR part 707, Workplace Substance Abuse Programs at DOE Sites, incorporated herein by reference...

  10. 48 CFR 970.5223-4 - Workplace Substance Abuse Programs at DOE Sites.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 5 2012-10-01 2012-10-01 false Workplace Substance Abuse... and Contract Clauses for Management and Operating Contracts 970.5223-4 Workplace Substance Abuse... 10 CFR part 707, Workplace Substance Abuse Programs at DOE Sites, incorporated herein by reference...

  11. 48 CFR 970.5223-4 - Workplace Substance Abuse Programs at DOE Sites.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 5 2014-10-01 2014-10-01 false Workplace Substance Abuse... and Contract Clauses for Management and Operating Contracts 970.5223-4 Workplace Substance Abuse... 10 CFR part 707, Workplace Substance Abuse Programs at DOE Sites, incorporated herein by reference...

  12. 48 CFR 970.5223-4 - Workplace Substance Abuse Programs at DOE Sites.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Workplace Substance Abuse... and Contract Clauses for Management and Operating Contracts 970.5223-4 Workplace Substance Abuse... 10 CFR part 707, Workplace Substance Abuse Programs at DOE Sites, incorporated herein by reference...

  13. 46 CFR 160.041-4 - Contents.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 6 2010-10-01 2010-10-01 false Contents. 160.041-4 Section 160.041-4 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Kits, First-Aid, for Merchant Vessels § 160.041-4 Contents. (a) Individual cartons. Cartons shall be of the...

  14. 46 CFR 160.041-4 - Contents.

    Code of Federal Regulations, 2010 CFR

    2005-10-01

    ... 46 Shipping 6 2005-10-01 2004-10-01 true Contents. 160.041-4 Section 160.041-4 Shipping Coast...: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Kits, First-Aid, for Merchant Vessels § 160.041-4 Contents. (a... Recommendation R178-41, properly labeled to designate the name, size of contents, and method of use, and shall...

  15. 46 CFR 160.041-4 - Contents.

    Code of Federal Regulations, 2010 CFR

    2012-10-01

    ... 46 Shipping 6 2012-10-01 2012-10-01 false Contents. 160.041-4 Section 160.041-4 Shipping COAST...: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Kits, First-Aid, for Merchant Vessels § 160.041-4 Contents. (a... Recommendation R178-41, properly labeled to designate the name, size of contents, and method of use, and shall...

  16. 46 CFR 160.041-4 - Contents.

    Code of Federal Regulations, 2010 CFR

    2007-10-01

    ... 46 Shipping 6 2007-10-01 2007-10-01 false Contents. 160.041-4 Section 160.041-4 Shipping Coast Guard, Department of Homeland Security (Continued) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Kits, First-Aid, for Merchant Vessels § 160.041-4 Contents. (a) Individual cartons. Cartons shall be of the...

  17. 46 CFR 160.041-4 - Contents.

    Code of Federal Regulations, 2014 CFR

    2001-10-01

    ... 46 Shipping 6 2001-10-01 2001-10-01 false Contents. 160.041-4 Section 160.041-4 Shipping Coast Guard, Department of Transportation-Continued EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Kits, First-Aid, for Merchant Vessels § 160.041-4 Contents. (a) Individual cartons. Cartons shall be of the standard...

  18. 48 CFR 2419.808 - Contract negotiation.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 6 2013-10-01 2013-10-01 false Contract negotiation. 2419.808 Section 2419.808 Federal Acquisition Regulations System DEPARTMENT OF HOUSING AND URBAN...) Program 2419.808 Contract negotiation. ...

  19. 48 CFR 2419.808 - Contract negotiation.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 6 2014-10-01 2014-10-01 false Contract negotiation. 2419.808 Section 2419.808 Federal Acquisition Regulations System DEPARTMENT OF HOUSING AND URBAN...) Program 2419.808 Contract negotiation. ...

  20. X-Ray System, Lightweight Medical (XRSLM)

    DTIC Science & Technology

    1992-08-10

    AD-25805 DTIC ELECTE DEC 3 1992 C~ontract No. DAMD 17-88(1-8058 X-Ray System , Lightweight Medical kXRSLM) M el in P .Siedba nl Frank C. G-reuzow’)N...Craig A. Hellman Robert C. Bruce rl 4 1W ý~( rf A&*- ~ko~.$~._ LO Contract No. DAMD17-88C-8058 X-Ray System , Lightweight Medical (XRSLM) Melvin P... System , Lightweight Medical (XRSLM) Contract No. DAMD17-88-C-805 8 6. AUTHOR(S)Melvin P. Siedband 63807A Frank C. Grenzow 3M463807L2336 HE 041 Craig A

  1. 48 CFR 3019.708 - Contract clauses.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 7 2010-10-01 2010-10-01 false Contract clauses. 3019.708 Section 3019.708 Federal Acquisition Regulations System DEPARTMENT OF HOMELAND SECURITY, HOMELAND SECURITY ACQUISITION REGULATION (HSAR) SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS The Small Business Subcontracting...

  2. 48 CFR 26.201 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... PROGRAMS OTHER SOCIOECONOMIC PROGRAMS Disaster or Emergency Assistance Activities 26.201 Definitions. Emergency response contract means a contract with private entities that supports assistance activities in a... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Definitions. 26.201...

  3. 48 CFR 219.808 - Contract negotiations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Contract negotiations. 219.808 Section 219.808 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM... Administration (The 8(a) Program) 219.808 Contract negotiations. ...

  4. 48 CFR 219.808 - Contract negotiations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Contract negotiations. 219.808 Section 219.808 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM... Administration (The 8(a) Program) 219.808 Contract negotiations. ...

  5. 48 CFR 219.808 - Contract negotiations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Contract negotiations. 219.808 Section 219.808 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM... Administration (The 8(a) Program) 219.808 Contract negotiations. ...

  6. 48 CFR 219.808 - Contract negotiations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Contract negotiations. 219.808 Section 219.808 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM... Administration (The 8(a) Program) 219.808 Contract negotiations. ...

  7. 48 CFR 219.808 - Contract negotiations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Contract negotiations. 219.808 Section 219.808 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM... Administration (The 8(a) Program) 219.808 Contract negotiations. ...

  8. 46 CFR § 160.041-4 - Contents.

    Code of Federal Regulations, 2010 CFR

    2006-10-01

    ... 46 Shipping 6 2006-10-01 2006-10-01 false Contents. § 160.041-4 Section § 160.041-4 Shipping Coast Guard, Department of Homeland Security (Continued) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Kits, First-Aid, for Merchant Vessels § 160.041-4 Contents. (a) Individual cartons. Cartons shall be of th...

  9. 46 CFR § 160.041-4 - Contents.

    Code of Federal Regulations, 2012 CFR

    2015-10-01

    ... 46 Shipping 6 2015-10-01 2015-10-01 false Contents. § 160.041-4 Section § 160.041-4 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Kits, First-Aid, for Merchant Vessels § 160.041-4 Contents. (a) Individual cartons. Cartons shall be of th...

  10. 46 CFR § 160.041-4 - Contents.

    Code of Federal Regulations, 2014 CFR

    2017-10-01

    ... 46 Shipping 6 2017-10-01 2017-10-01 false Contents. § 160.041-4 Section § 160.041-4 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Kits, First-Aid, for Merchant Vessels § 160.041-4 Contents. (a) Individual cartons. Cartons shall be of th...

  11. 48 CFR 2132.772 - Contract clause.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Contract clause. 2132.772 Section 2132.772 Federal Acquisition Regulations System OFFICE OF PERSONNEL MANAGEMENT, FEDERAL EMPLOYEES... Contract Funding 2132.772 Contract clause. The clause at 2152.232-71 shall be inserted in all FEGLI Program...

  12. 48 CFR 1819.708 - Contract clauses. (NASA supplements paragraph (b))

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 6 2013-10-01 2013-10-01 false Contract clauses. (NASA supplements paragraph (b)) 1819.708 Section 1819.708 Federal Acquisition Regulations System NATIONAL... Subcontracting Program 1819.708 Contract clauses. (NASA supplements paragraph (b)) (b)(1) The contracting officer...

  13. 48 CFR 1819.708 - Contract clauses. (NASA supplements paragraph (b))

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Contract clauses. (NASA supplements paragraph (b)) 1819.708 Section 1819.708 Federal Acquisition Regulations System NATIONAL... Subcontracting Program 1819.708 Contract clauses. (NASA supplements paragraph (b)) (b)(1) The contracting officer...

  14. 48 CFR 1819.708 - Contract clauses. (NASA supplements paragraph (b))

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 6 2012-10-01 2012-10-01 false Contract clauses. (NASA supplements paragraph (b)) 1819.708 Section 1819.708 Federal Acquisition Regulations System NATIONAL... Subcontracting Program 1819.708 Contract clauses. (NASA supplements paragraph (b)) (b)(1) The contracting officer...

  15. 48 CFR 1819.708 - Contract clauses. (NASA supplements paragraph (b))

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 6 2014-10-01 2014-10-01 false Contract clauses. (NASA supplements paragraph (b)) 1819.708 Section 1819.708 Federal Acquisition Regulations System NATIONAL... Subcontracting Program 1819.708 Contract clauses. (NASA supplements paragraph (b)) (b)(1) The contracting officer...

  16. 48 CFR 1819.708 - Contract clauses. (NASA supplements paragraph (b))

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 6 2011-10-01 2011-10-01 false Contract clauses. (NASA supplements paragraph (b)) 1819.708 Section 1819.708 Federal Acquisition Regulations System NATIONAL... Subcontracting Program 1819.708 Contract clauses. (NASA supplements paragraph (b)) (b)(1) The contracting officer...

  17. In vivo evidence for the involvement of tachykinin NK3 receptors in the hexamethonium-resistant inhibitory transmission in the rat colon.

    PubMed

    Lecci, A; Giuliani, S; Tramontana, M; Meini, S; De Giorgio, R; Maggi, C A

    1996-05-01

    In urethane-anaesthetized rats, moderate colonic distention (0.5 ml) induced reflex rhythmic contractions (5 mm Hg amplitude and 1.1 cycles/min frequency). Senktide (1-10 nmol/kg, i.v.), a tachykinin NK3 receptor selective agonist, transiently suppressed distension-induced contractions. SR 142,801 (1-10 mumol/kg i.v.), a non-peptide tachykinin NK3 receptor antagonist, had no effect on distension-induced contractions but prevented the inhibitory effect of senktide. Infusion of N-omega-nitro-1-arginine methyl esther hydrochloride (L-NAME, 20 mumol/ml/h, i.v) increased the amplitude of colonic contractions and decreased the inhibitory effect of senktide. Hexamethonium (15 mumol/ml/h, i.v.) or atropine (1 mumol/ml/h, i.v.) inhibited the distension-induced contractions. In hexamethonium- or atropine-treated rats, senktide (10 nmol/kg) transiently and selectively enhanced the amplitude of contractions. Also SR 142,801 (10 mumol/kg), but not its inactive enantiomer SR 142,806, increased both amplitude and frequency of contractions. During continuous infusion of L-NAME and hexamethonium or atropine both frequency and amplitude of distension-induced colonic contractions were higher than when in hexamethonium or atropine only. Senktide (10 nmol/kg) had no effect and SR 142,801 (10 mumol/kg) produced a slight enhancement of colonic contractions. Infusion of sodium nitroprusside (3 mumol/ml/h, i.v.) decreased amplitude and frequency of distension-induced contractions. SR 142,801 had no effect in the presence of the nitric oxide (NO) donor. We conclude that tachykinins acting through NK3 receptors exert at least four different actions on colonic motility activated by distension: 1) a hexamethonium-resistant, NO-dependent, suppressant effect on contractions; 2) a hexamethonium-sensitive, NO-independent inhibitory effect on the amplitude of contractions; 3) a hexamethonium-resistant, NO-independent inhibitory effect on the amplitude of contractions and 4) a hexamethonium resistant and L-NAME-sensitive excitatory effect on amplitude of contractions. The prevalent inhibitory effect evoked in normal conditions along with the excitatory activity induced by SR 142,801 on hexamethonium-resistant colonic motility indicates that tachykinins, acting through neuronal NK3 receptors, activate NO-dependent and NO-independent inhibitory neurotransmission in the rat colon.

  18. 48 CFR 19.602-4 - Awarding the contract.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Awarding the contract. 19.602-4 Section 19.602-4 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Certificates of Competency and Determinations of Responsibility...

  19. 48 CFR 19.806 - Pricing the 8(a) contract.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Pricing the 8(a) contract...) Program) 19.806 Pricing the 8(a) contract. (a) The contracting officer shall price the 8(a) contract in accordance with subpart 15.4. If required by subpart 15.4, the SBA shall obtain certified cost or pricing...

  20. 48 CFR 1819.708-70 - NASA solicitation provision and contract clause.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true NASA solicitation provision and contract clause. 1819.708-70 Section 1819.708-70 Federal Acquisition Regulations System NATIONAL... Subcontracting Program 1819.708-70 NASA solicitation provision and contract clause. (a) The contracting officer...

  1. 48 CFR 22.1003-5 - Some examples of contracts covered.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Some examples of contracts... SOCIOECONOMIC PROGRAMS APPLICATION OF LABOR LAWS TO GOVERNMENT ACQUISITIONS Service Contract Act of 1965, as Amended 22.1003-5 Some examples of contracts covered. The following examples, while not definitive or...

  2. 43 CFR 422.9 - Reclamation law enforcement contracts and cooperative agreements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false Reclamation law enforcement contracts and... PROJECTS Program Requirements § 422.9 Reclamation law enforcement contracts and cooperative agreements. (a... Federal laws. (b) Each contract and cooperative agreement authorizing the exercise of Reclamation law...

  3. 48 CFR 819.7004 - Contracting Order of Priority.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Contracting Order of Priority. 819.7004 Section 819.7004 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Service-Disabled Veteran-Owned and Veteran-Owned Small Business...

  4. 48 CFR 819.7004 - Contracting Order of Priority.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 5 2012-10-01 2012-10-01 false Contracting Order of Priority. 819.7004 Section 819.7004 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Service-Disabled Veteran-Owned and Veteran-Owned Small Business...

  5. 48 CFR 917.7301 - Policy.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Policy. 917.7301 Section 917.7301 Federal Acquisition Regulations System DEPARTMENT OF ENERGY CONTRACTING METHODS AND CONTRACT TYPES SPECIAL CONTRACTING METHODS Program Research and Development Announcements 917.7301 Policy. ...

  6. 48 CFR 2144.102 - Policy.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 6 2014-10-01 2014-10-01 false Policy. 2144.102 Section... LIFE INSURANCE FEDERAL ACQUISITION REGULATION CONTRACT MANAGEMENT SUBCONTRACTING POLICIES AND PROCEDURES General 2144.102 Policy. For all FEGLI Program contracts, the Contracting Officer's advance...

  7. 48 CFR 2144.102 - Policy.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Policy. 2144.102 Section... LIFE INSURANCE FEDERAL ACQUISITION REGULATION CONTRACT MANAGEMENT SUBCONTRACTING POLICIES AND PROCEDURES General 2144.102 Policy. For all FEGLI Program contracts, the Contracting Officer's advance...

  8. 48 CFR 2144.102 - Policy.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 6 2012-10-01 2012-10-01 false Policy. 2144.102 Section... LIFE INSURANCE FEDERAL ACQUISITION REGULATION CONTRACT MANAGEMENT SUBCONTRACTING POLICIES AND PROCEDURES General 2144.102 Policy. For all FEGLI Program contracts, the Contracting Officer's advance...

  9. 41 CFR 51-10.160 - Communications.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true Communications. 51-10.160 Section 51-10.160 Public Contracts and Property Management Other Provisions Relating to Public Contracts... would result in a fundamental alteration in the nature of a program or activity or in undue financial...

  10. 41 CFR 102-193.10 - What are the goals of the Federal Records Management Program?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... maintenance of management controls that prevent the creation of unnecessary records and promote effective and... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false What are the goals of the Federal Records Management Program? 102-193.10 Section 102-193.10 Public Contracts and Property...

  11. 48 CFR 719.273-11 - Solicitation provision and contract clause.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Solicitation provision and contract clause. 719.273-11 Section 719.273-11 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS The U.S. Agency for International...

  12. 48 CFR 719.273-11 - Solicitation provision and contract clause.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Solicitation provision and contract clause. 719.273-11 Section 719.273-11 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS The U.S. Agency for International...

  13. Reforming the Joint Military Establishment

    DTIC Science & Technology

    1985-06-01

    FOR PUBLIC RELEASE DISTRIBUTION UNLIMITED D UNCLASSIFIED StCURITV CLASJiriCATIOM OP THIS PAOK (*h*> Dmf Enltfd) REPORT DOCUMENTATION PAGE 1...COMPLETING FORM i Rt t lRNT’S CATALOG NUMBER 5. TYPE OF HEBORT 4 PCRIOC COVCRCO Final S. PERFORMING ORO. REPORT NUMICR B. CONTRACT OR GRANT...NUMBERft; 10. PROGRAM ELCMENT. PROJECT, TASK AREA ft WORK UNIT NUMBERS U. REPORT OAT1 June 1985 𔃽. NUMBER OF PAGES 78 IS. SECURITY CLASS

  14. 42 CFR 417.427 - Extending MA and Part D program disclosure requirements to section 1876 cost contract plans.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 3 2014-10-01 2014-10-01 false Extending MA and Part D program disclosure..., and Disenrollment under Medicare Contract § 417.427 Extending MA and Part D program disclosure... chapter must be read as references to this part, and references to MA organizations and Part D sponsors as...

  15. 42 CFR 417.427 - Extending MA and Part D program disclosure requirements to section 1876 cost contract plans.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 3 2013-10-01 2013-10-01 false Extending MA and Part D program disclosure..., and Disenrollment under Medicare Contract § 417.427 Extending MA and Part D program disclosure... chapter must be read as references to this part, and references to MA organizations and Part D sponsors as...

  16. 42 CFR 417.427 - Extending MA and Part D program disclosure requirements to section 1876 cost contract plans.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 3 2012-10-01 2012-10-01 false Extending MA and Part D program disclosure..., and Disenrollment under Medicare Contract § 417.427 Extending MA and Part D program disclosure... chapter must be read as references to this part, and references to MA organizations and Part D sponsors as...

  17. 48 CFR 370.304 - Contract clauses.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 4 2011-10-01 2011-10-01 false Contract clauses. 370.304 Section 370.304 Federal Acquisition Regulations System HEALTH AND HUMAN SERVICES HHS SUPPLEMENTATIONS SPECIAL PROGRAMS AFFECTING ACQUISITION Acquisitions Involving Human Subjects 370.304 Contract clauses. (a...

  18. Regulation of the substance P-induced contraction via the release of acetylcholine and gamma-aminobutyric acid in the guinea-pig urinary bladder.

    PubMed Central

    Shirakawa, J.; Nakanishi, T.; Taniyama, K.; Kamidono, S.; Tanaka, C.

    1989-01-01

    1. The action of substance P (SP) on the release of gamma-aminobutyric acid (GABA) and acetylcholine (ACh) and on contraction were studied in strips of the guinea-pig urinary bladder. Substance P induced a dose-dependent contraction of strips of guinea-pig urinary bladder (EC50 = 1.2 x 10(-9) M). This contraction was not altered by tetrodotoxin, but with a dose of 10(-9) M and less, there was a complete inhibition by 10(-6) M) atropine. Contractions initiated by 3 x 10(-9) M) SP or more were partly inhibited by atropine. The EC50 value of substance P in the presence of atropine was 7.0 x 10(-9) M. 2. Substance P induced a Ca2+-dependent and tetrodotoxin-resistant release of [3H]-acetylcholine (ACh) from strips of urinary bladder preloaded with [3H]-choline (EC50 = 4.9 x 10(-10) M), and this release was antagonized by [D-Pro2,D-Trp7,9] substance P. 3. Bicuculline increased the substance P-induced contraction and the release of [3H]-ACh from the strips. 4. Substance P induced a Ca2+-dependent and tetrodotoxin-sensitive release of [3H]-gamma-aminobutyric acid (GABA) from strips preloaded with [3H]-GABA (EC50 = 2.6 x 10(-9) M), and this release was antagonized by [D-Pro2,D-Trp7,9] substance P. 5. Therefore, substance P appears to exert excitatory effects on the contractility of urinary bladder predominantly by stimulating its own receptor located on the cholinergic nerve terminals. GABA released by substance P inhibits stimulation of the cholinergic neurone. However, the direct action of substance P on the cholinergic neurone is more potent that the indirect action via GABA release. PMID:2479440

  19. 42 CFR 460.70 - Contracted services.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 4 2011-10-01 2011-10-01 false Contracted services. 460.70 Section 460.70 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) PROGRAMS OF ALL-INCLUSIVE CARE FOR THE ELDERLY (PACE) PROGRAMS OF ALL-INCLUSIVE CARE FOR THE ELDERLY (PACE...

  20. 42 CFR 460.70 - Contracted services.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Contracted services. 460.70 Section 460.70 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) PROGRAMS OF ALL-INCLUSIVE CARE FOR THE ELDERLY (PACE) PROGRAMS OF ALL-INCLUSIVE CARE FOR THE ELDERLY (PACE...

  1. 42 CFR 422.220 - Exclusion of services furnished under a private contract.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Exclusion of services furnished under a private contract. 422.220 Section 422.220 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICARE PROGRAM MEDICARE ADVANTAGE PROGRAM Relationships With...

  2. 48 CFR 317.207 - Exercise of options.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Exercise of options. 317... METHODS AND CONTRACT TYPES SPECIAL CONTRACTING METHODS Options 317.207 Exercise of options. (h) Before exercising an option for a subsequent performance period/additional quantity under a multiple-year contract...

  3. 48 CFR 317.207 - Exercise of options.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 4 2012-10-01 2012-10-01 false Exercise of options. 317... METHODS AND CONTRACT TYPES SPECIAL CONTRACTING METHODS Options 317.207 Exercise of options. (h) Before..., and the Section 508 Official or designee, prior to exercise of an option. The Contracting Officer...

  4. 48 CFR 317.207 - Exercise of options.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 4 2013-10-01 2013-10-01 false Exercise of options. 317... METHODS AND CONTRACT TYPES SPECIAL CONTRACTING METHODS Options 317.207 Exercise of options. (h) Before..., and the Section 508 Official or designee, prior to exercise of an option. The Contracting Officer...

  5. 48 CFR 317.207 - Exercise of options.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 4 2011-10-01 2011-10-01 false Exercise of options. 317... METHODS AND CONTRACT TYPES SPECIAL CONTRACTING METHODS Options 317.207 Exercise of options. (h) Before..., and the Section 508 Official or designee, prior to exercise of an option. The Contracting Officer...

  6. 48 CFR 317.207 - Exercise of options.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 4 2014-10-01 2014-10-01 false Exercise of options. 317... METHODS AND CONTRACT TYPES SPECIAL CONTRACTING METHODS Options 317.207 Exercise of options. (h) Before..., and the Section 508 Official or designee, prior to exercise of an option. The Contracting Officer...

  7. 48 CFR 622.1408 - Contract clause.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Contract clause. 622.1408 Section 622.1408 Federal Acquisition Regulations System DEPARTMENT OF STATE SOCIOECONOMIC PROGRAMS APPLICATION OF LABOR LAWS TO GOVERNMENT ACQUISITIONS Employment of Workers with Disabilities 622.1408 Contract...

  8. 48 CFR 22.1202 - Policy.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 1 2013-10-01 2013-10-01 false Policy. 22.1202 Section 22.1202 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SOCIOECONOMIC PROGRAMS... Contracts 22.1202 Policy. (a) When a service contract succeeds a contract for performance of the same or...

  9. 47 CFR 54.604 - Consortia, telecommunications services, and existing contracts.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 3 2014-10-01 2014-10-01 false Consortia, telecommunications services, and existing contracts. 54.604 Section 54.604 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED... Telecommunications Program § 54.604 Consortia, telecommunications services, and existing contracts. (a) Consortia. (1...

  10. 47 CFR 54.604 - Consortia, telecommunications services, and existing contracts.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 3 2013-10-01 2013-10-01 false Consortia, telecommunications services, and existing contracts. 54.604 Section 54.604 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED... Telecommunications Program § 54.604 Consortia, telecommunications services, and existing contracts. (a) Consortia. (1...

  11. Systemic inflammatory responses to maximal versus submaximal lengthening contractions of the elbow flexors.

    PubMed

    Peake, Jonathan M; Nosaka, Kazunori; Muthalib, Makii; Suzuki, Katsuhiko

    2006-01-01

    We compared changes in markers of muscle damage and systemic inflammation after submaximal and maximal lengthening muscle contractions of the elbow flexors. Using a cross-over design, 10 healthy young men not involved in resistance training completed a submaximal trial (10 sets of 60 lengthening contractions at 10% maximum isometric strength, 1 min rest between sets), followed by a maximal trial (10 sets of three lengthening contractions at 100% maximum isometric strength, 3 min rest between sets). Lengthening contractions were performed on an isokinetic dynamometer. Opposite arms were used for the submaximal and maximal trials, and the trials were separated by a minimum of two weeks. Blood was sampled before, immediately after, 1 h, 3 h, and 1-4 d after each trial. Total leukocyte and neutrophil numbers, and the serum concentration of soluble tumor necrosis factor-alpha receptor 1 were elevated after both trials (P < 0.01), but there were no differences between the trials. Serum IL-6 concentration was elevated 3 h after the submaximal contractions (P < 0.01). The concentrations of serum tumor necrosis factor-alpha, IL-1 receptor antagonist, IL-10, granulocyte-colony stimulating factor and plasma C-reactive protein remained unchanged following both trials. Maximum isometric strength and range of motion decreased significantly (P < 0.001) after both trials, and were lower from 1-4 days after the maximal contractions compared to the submaximal contractions. Plasma myoglobin concentration and creatine kinase activity, muscle soreness and upper arm circumference all increased after both trials (P < 0.01), but were not significantly different between the trials. Therefore, there were no differences in markers of systemic inflammation, despite evidence of greater muscle damage following maximal versus submaximal lengthening contractions of the elbow flexors.

  12. 48 CFR 219.806 - Pricing the 8(a) contract.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Pricing the 8(a) contract... Administration (The 8(a) Program) 219.806 Pricing the 8(a) contract. For requirements processed under the PA cited in 219.800— (1) The contracting officer shall obtain cost or pricing data from the 8(a) contractor...

  13. 48 CFR 725.705 - Local procurement-contract clause.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Local procurement-contract... DEVELOPMENT SOCIOECONOMIC PROGRAMS FOREIGN ACQUISITION Source, Origin, and Nationality 725.705 Local procurement—contract clause. Local procurement may be undertaken in accordance with the provisions of 22 CFR...

  14. 48 CFR 725.705 - Local procurement-contract clause.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Local procurement-contract... DEVELOPMENT SOCIOECONOMIC PROGRAMS FOREIGN ACQUISITION Source, Origin, and Nationality 725.705 Local procurement—contract clause. Local procurement may be undertaken in accordance with the provisions of 22 CFR...

  15. Isometric exercise induces analgesia and reduces inhibition in patellar tendinopathy.

    PubMed

    Rio, Ebonie; Kidgell, Dawson; Purdam, Craig; Gaida, Jamie; Moseley, G Lorimer; Pearce, Alan J; Cook, Jill

    2015-10-01

    Few interventions reduce patellar tendinopathy (PT) pain in the short term. Eccentric exercises are painful and have limited effectiveness during the competitive season. Isometric and isotonic muscle contractions may have an immediate effect on PT pain. This single-blinded, randomised cross-over study compared immediate and 45 min effects following a bout of isometric and isotonic muscle contractions. Outcome measures were PT pain during the single-leg decline squat (SLDS, 0-10), quadriceps strength on maximal voluntary isometric contraction (MVIC), and measures of corticospinal excitability and inhibition. Data were analysed using a split-plot in time-repeated measures analysis of variance (ANOVA). 6 volleyball players with PT participated. Condition effects were detected with greater pain relief immediately from isometric contractions: isometric contractions reduced SLDS (mean±SD) from 7.0±2.04 to 0.17±0.41, and isotonic contractions reduced SLDS (mean±SD) from 6.33±2.80 to 3.75±3.28 (p<0.001). Isometric contractions released cortical inhibition (ratio mean±SD) from 27.53%±8.30 to 54.95%±5.47, but isotonic contractions had no significant effect on inhibition (pre 30.26±3.89, post 31.92±4.67; p=0.004). Condition by time analysis showed pain reduction was sustained at 45 min postisometric but not isotonic condition (p<0.001). The mean reduction in pain scores postisometric was 6.8/10 compared with 2.6/10 postisotonic. MVIC increased significantly following the isometric condition by 18.7±7.8%, and was significantly higher than baseline (p<0.001) and isotonic condition (p<0.001), and at 45 min (p<0.001). A single resistance training bout of isometric contractions reduced tendon pain immediately for at least 45 min postintervention and increased MVIC. The reduction in pain was paralleled by a reduction in cortical inhibition, providing insight into potential mechanisms. Isometric contractions can be completed without pain for people with PT. The clinical implications are that isometric muscle contractions may be used to reduce pain in people with PT without a reduction in muscle strength. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  16. Differential regulation of smooth muscle contraction in rabbit internal anal sphincter by substance P and bombesin.

    PubMed

    Bitar, K N; Hillemeier, C; Biancani, P

    1990-01-01

    Substance P and bombesin induce contraction of isolated IAS smooth muscle cells by different intracellular mechanisms. The cells contracted in a dose dependent manner to both peptides. The kinetics of contraction were different. Substance P induced contraction peaked at 30 seconds and declined in a time dependent manner while bombesin induced contraction peaked at 30 seconds and was maintained for up to 8 minutes. The absence of extracellular calcium in the medium (0 calcium and 2 mM EGTA) had no affect on substance P induced contraction while it blocked bombesin induced contraction. Substance P induced contraction was blocked by the calmodulin antagonist W7 (10(-9)M) and was not affected by the PKC antagonist H7 (10(-6)M). Bombesin induced contraction was blocked by the PKC antagonist H7 and was not affected by the calmodulin antagonist W7. Our data indicate that substance P induces a transient contraction utilizing intracellular calcium and a calmodulin dependent pathway, while bombesin induces a sustained contraction utilizing calcium from extracellular sources and a calmodulin independent pathway.

  17. 46 CFR 160.041-1 - Applicable specification and publication.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 6 2011-10-01 2011-10-01 false Applicable specification and publication. 160.041-1... Vessels § 160.041-1 Applicable specification and publication. (a) Specification. The following... Contents. (b) Publication. The following publication, of the issue in effect on the date first-aid kits are...

  18. 46 CFR 160.041-1 - Applicable specification and publication.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 6 2012-10-01 2012-10-01 false Applicable specification and publication. 160.041-1... Vessels § 160.041-1 Applicable specification and publication. (a) Specification. The following... Contents. (b) Publication. The following publication, of the issue in effect on the date first-aid kits are...

  19. 48 CFR 1819.708-70 - NASA solicitation provision and contract clause.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 6 2013-10-01 2013-10-01 false NASA solicitation provision and contract clause. 1819.708-70 Section 1819.708-70 Federal Acquisition Regulations System... Business Subcontracting Program 1819.708-70 NASA solicitation provision and contract clause. (a) The...

  20. 48 CFR 1819.708-70 - NASA solicitation provision and contract clause.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 6 2011-10-01 2011-10-01 false NASA solicitation provision and contract clause. 1819.708-70 Section 1819.708-70 Federal Acquisition Regulations System... Business Subcontracting Program 1819.708-70 NASA solicitation provision and contract clause. (a) The...

  1. 48 CFR 1819.708-70 - NASA solicitation provision and contract clause.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 6 2012-10-01 2012-10-01 false NASA solicitation provision and contract clause. 1819.708-70 Section 1819.708-70 Federal Acquisition Regulations System... Business Subcontracting Program 1819.708-70 NASA solicitation provision and contract clause. (a) The...

  2. 48 CFR 1819.708-70 - NASA solicitation provision and contract clause.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 6 2014-10-01 2014-10-01 false NASA solicitation provision and contract clause. 1819.708-70 Section 1819.708-70 Federal Acquisition Regulations System... Business Subcontracting Program 1819.708-70 NASA solicitation provision and contract clause. (a) The...

  3. 42 CFR 438.356 - State contract options.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false State contract options. 438.356 Section 438.356 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS MANAGED CARE External Quality Review § 438.356 State contract options...

  4. Defense Procurement: An Analysis of Contract Management Internal Controls

    DTIC Science & Technology

    2015-03-22

    monitoring activities component of the internal control framework. Acquisition Research Program Graduate School of Business & Public Policy - 7...Research Program Graduate School of Business & Public Policy - 24 - Naval Postgraduate School Tan, L. H. J. (2013). An analysis of internal controls and...Naval Postgraduate School, Monterey, CA 93943. Defense Procurement: An Analysis of Contract Management Internal Controls 22 March 2015 Dr. Juanita

  5. 42 CFR 405.415 - Requirements of the private contract.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 2 2010-10-01 2010-10-01 false Requirements of the private contract. 405.415 Section 405.415 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES MEDICARE PROGRAM FEDERAL HEALTH INSURANCE FOR THE AGED AND DISABLED Private Contracts § 405.415...

  6. 42 CFR 405.455 - Application to Medicare+Choice contracts.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 2 2010-10-01 2010-10-01 false Application to Medicare+Choice contracts. 405.455 Section 405.455 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES MEDICARE PROGRAM FEDERAL HEALTH INSURANCE FOR THE AGED AND DISABLED Private Contracts § 405.455...

  7. 40 CFR 160.10 - Applicability to studies performed under grants and contracts.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Applicability to studies performed under grants and contracts. 160.10 Section 160.10 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS GOOD LABORATORY PRACTICE STANDARDS General Provisions § 160.10...

  8. Oil and Hazardous Material Cleanup Liability: A Study of Legal and Administrative Efficiency.

    DTIC Science & Technology

    1980-01-01

    sec. 1161 (1972). 6 extensive network of support equipment and the support people who contract, audit invoices, train, and manage budgets and programs...tediously describing the intricate aspects of documentation, auditing , forms, Ś The most notable "Superfund" type bill in the 96th Congress is H.R. 85. 10...Workshop on Reducing Tankbarge Pollution, 15 and 16 April 1980. (Typewritten). 21 the primary source of oil polution .16 Second, vessel source pollution

  9. 42 CFR 421.200 - Carrier functions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Carrier functions. 421.200 Section 421.200 Public...) MEDICARE PROGRAM MEDICARE CONTRACTING Carriers § 421.200 Carrier functions. A contract between CMS and a carrier specifies the functions to be performed by the carrier. The contract may include any or all of the...

  10. 40 CFR 86.096-8 - Emission standards for 1996 and later model year light-duty vehicles.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Fueled, Natural Gas-Fueled, Liquefied Petroleum Gas-Fueled and Methanol-Fueled Heavy-Duty Vehicles § 86... NMHCE CO NOX PM Gasoline 0.41 0.25 3.4 0.4 0.08 Diesel 0.41 0.25 3.4 1.0 0.08 Methanol 0.41 0.25 3.4 0.4....31 4.2 1.25 0.10 Methanol 0.31 4.2 0.6 0.10 Natural Gas 0.31 4.2 0.6 0.10 LPG 0.31 4.2 0.6 0.10 (ii...

  11. 40 CFR 86.096-8 - Emission standards for 1996 and later model year light-duty vehicles.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Fueled, Natural Gas-Fueled, Liquefied Petroleum Gas-Fueled and Methanol-Fueled Heavy-Duty Vehicles § 86... NMHCE CO NOX PM Gasoline 0.41 0.25 3.4 0.4 0.08 Diesel 0.41 0.25 3.4 1.0 0.08 Methanol 0.41 0.25 3.4 0.4....31 4.2 1.25 0.10 Methanol 0.31 4.2 0.6 0.10 Natural Gas 0.31 4.2 0.6 0.10 LPG 0.31 4.2 0.6 0.10 (ii...

  12. Endothelial cell-dependent relaxation and contraction induced by histamine in the isolated guinea-pig pulmonary artery.

    PubMed

    Satoh, H; Inui, J

    1984-01-27

    Histamine (10(-8)-10(-6) M) relaxed in a concentration-dependent manner the guinea-pig pulmonary artery which had been contracted by noradrenaline (5 X 10(-7) M). After the removal of endothelial cells (ETCs) histamine at the same concentrations did not cause relaxation but induced additional contraction. Both responses to histamine were antagonized by chlorpheniramine (3 X 10(-7) M). These results suggest that in the pulmonary artery histamine simultaneously stimulates H1-receptors located on both ETCs and smooth muscle cells. This results in two opposite effects, relaxation mediated by ETCs, and contraction.

  13. Validation of ‘POIBA-How do we eat?’ questionnaire in 9-10 years old schoolchildren

    PubMed Central

    Ariza, Carles; Arechavala, Teresa; Valmayor, Sara; Serral, Gemma; Moncada, Albert; Rajmil, Luis; Schiaffino, Anna; Sánchez-Martínez, Francesca

    2017-01-01

    ABSTRACT Background: It is difficult to obtain good food reports with Food Frequency Questionnaires (FFQ) among children. In addition, validated questionnaires are scarce. Objective: The aim of this study was to validate the ‘POIBA-How do we eat?’ (POIBA-HDWE) FFQ and whether it could be administered to children under 10 years of age. Design: We validated the FFQ POIBA-HDWE as part of the Childhood Obesity Prevention Program (POIBA project) in Barcelona. Forty-two out of 63 primary school students (9–10 years old) answered three questionnaires: FFQ POBA-HDWE; another questionnaire, ‘POIBA-How do our children eat?’ (POIBA-HDOCE), which was administered to the children’s parents; and the 24-h recall computer program ‘Young Adolescents’ Nutrition Assessment on Computer’ (YANA-C), which was used on three different days as a gold standard. We tested for correlations using the Spearman test for non-parametric variables. Results: We found low compliance with food recommendations (<50%). The POIBA-HDWE and POIBA-HDOCE questionnaires showed a moderate correlation for soft drinks (r = 0.49; p < 0.01), nuts (r = 0.59; p < 0.01), dairy products (r = 0.41; p < 0.01) and juices (r = 0.49; p < 0.01). There were moderate correlations between POIBA-HDWE and YANA-C for fried potatoes (r = 0.42; p = 0.01), dairy products (r = 0.53; p < 0.01), juices (r = 0.41; p < 0.01), and grains(r = 0.50; p < 0.01). Food frequency questions showed a homogeneity of 0.69, and a sensitivity of over 60% for all food items except chips (37.5%) and sweets (51.7%). Conclusions: The POIBA-HDWE FFQ showed moderate correlations with the gold standard, high sensitivity for most food types and acceptable internal consistency. It is an easy and affordable tool for recording food frequency in children under 10 years old. PMID:29151829

  14. 48 CFR 217.173 - Multiyear contracts for weapon systems.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... weapon systems. 217.173 Section 217.173 Federal Acquisition Regulations System DEFENSE ACQUISITION... Mulityear Contracting 217.173 Multiyear contracts for weapon systems. As authorized by 10 U.S.C. 2306b(h... contract for— (a) A weapon system and associated items, services, and logistics support for a weapon system...

  15. Operation and Hydrodynamic Evaluations of a Controlled-Depth Towed Depressor Designed to House a Conductivity, Temperature, Depth (CTD) Instrument System

    DTIC Science & Technology

    1981-03-01

    ljIi 0 10 20 30 40 50 60 70 80 LENGTH (W) Figure 2 - Predicted Tension in Remote Sensor Cable at 10 Knots as a Function of Cable Length for Two Remote...10.0 -8.0 -10 4.11 0.68 40 5.0 -8.0 -15 0.66 0.44 41 8.0 -8.0 -15 1.57 0.41 42 10.0 -8.0 -15 2.63 0.44 43 5.0 -8.0 -20 0.48 0.32 44 8.0 -8.0 -20 0.89...HH fIH 1 IH r-4 H r- rIH rIH 4 i HHH.-4H H -4 rIH HHHHH r Cfr- 40 00 0 0q - zI - ri-4- oi 0 -A- \\.o. m M- r-. A- - rA- r-c r(0 P4 r

  16. 75 FR 10645 - Low Pathogenic Avian Influenza; Voluntary Control Program and Payment of Indemnity

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-09

    ...We are adopting as a final rule, with changes, an interim rule that amended the regulations by establishing, under the auspices of the National Poultry Improvement Plan, a voluntary program for the control of the H5/H7 subtypes of low pathogenic avian influenza in commercial poultry. As amended by this document, the rule provides that the amount of indemnity for which contract growers are eligible will be reduced by any payment they have already received on their contracts when poultry in their care are destroyed, clarifies the roles of cooperating State agencies with respect to H5/H7 low pathogenic avian influenza outbreaks, provides that consistency with humane euthanasia guidelines will be considered when selecting a method for the destruction of poultry, and provides additional guidance for cleaning and disinfecting an affected premises. The control program and indemnity provisions established by the interim rule are necessary to help ensure that the H5/H7 subtypes of low pathogenic avian influenza are detected and eradicated when they occur within the United States.

  17. Contracts and Management Services FY 1996 Site Support Program Plan: WBS 6.10.14. Revision 1

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Knoll, J.M. Jr.

    1995-09-01

    This is the Contracts and Management Services site support program plan for the US DOE Hanford site. The topics addressed in the program plan include a mission statement, program objectives, planning assumptions, program constraints, work breakdown structure, milestone list, milestone description sheets, and activity detail including cost accounting narrative summary, approved funding budget, and activity detailed description.

  18. Human urotensin-II is a potent spasmogen of primate airway smooth muscle

    PubMed Central

    Hay, Douglas W P; Luttmann, Mark A; Douglas, Stephen A

    2000-01-01

    The contractile profile of human urotensin-II (hU-II) was examined in primate airway and pulmonary vascular tissues. hU-II contracted tissues from different airway regions with similar potencies (pD2s from 8.6 to 9.2). However, there were regional differences in the efficacy of hU-II, with a progressive increase in the maximum contraction from trachea to smaller airway regions (from 9 to 41% of the contraction to 10 μM carbachol). hU-II potently contracted pulmonary artery tissues from different regions with similar potencies and efficacies: pD2s=8.7 to 9.3 and maximal contractions=79 to 86% of 60 mM KCl. hU-II potently contracted pulmonary vein preparations taken proximal to the atria, but had no effect in tissues from distal to the atria. This is the first report describing the contractile activity of hU-II in airways and suggests that the potential pathophysiological role of this peptide in lung diseases warrants investigation. PMID:10960062

  19. Specification Section 01065S ES&H for Service Contracts

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kirsch, Greg C.

    2014-07-01

    Section Includes: Requirements and guidelines in performance of work concerning protection of environment and property, and the safety and health of Contractors, Sandia National Laboratories (SNL) and Department of Energy (DOE) employees, visitors to SNL, and members of the public. This Section is applicable only to Service Contracts that do not involve construction or construction-like activities. Construction and construction-like activities are covered by Section 01065, Environment, Safety and Health (ES&H) for Construction Contracts. The entire ES&H program shall focus on safe-by-design intent, understanding the technical basis for the work, identifying and controlling energy sources, unacceptable consequences, risk assessments, and positivemore » verification.« less

  20. 48 CFR 904.7101 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 5 2013-10-01 2013-10-01 false Definitions. 904.7101 Section 904.7101 Federal Acquisition Regulations System DEPARTMENT OF ENERGY GENERAL ADMINISTRATIVE MATTERS Prohibition on Contracting (National Security Program Contracts) 904.7101 Definitions. Effectively...

  1. 48 CFR 904.7101 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Definitions. 904.7101 Section 904.7101 Federal Acquisition Regulations System DEPARTMENT OF ENERGY GENERAL ADMINISTRATIVE MATTERS Prohibition on Contracting (National Security Program Contracts) 904.7101 Definitions. Effectively...

  2. 48 CFR 1223.7000 - Contract clauses.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Contract clauses. 1223.7000 Section 1223.7000 Federal Acquisition Regulations System DEPARTMENT OF TRANSPORTATION SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY TECHNOLOGIES, OCCUPATIONAL...

  3. 48 CFR 1223.7000 - Contract clauses.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 5 2014-10-01 2014-10-01 false Contract clauses. 1223.7000 Section 1223.7000 Federal Acquisition Regulations System DEPARTMENT OF TRANSPORTATION SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY TECHNOLOGIES, OCCUPATIONAL...

  4. 48 CFR 1223.7000 - Contract clauses.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 5 2013-10-01 2013-10-01 false Contract clauses. 1223.7000 Section 1223.7000 Federal Acquisition Regulations System DEPARTMENT OF TRANSPORTATION SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY TECHNOLOGIES, OCCUPATIONAL...

  5. 48 CFR 1615.402 - Pricing policy.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Pricing policy. 1615.402... Contract Pricing 1615.402 Pricing policy. Pricing of FEHB contracts is governed by 5 U.S.C. 8902(i), 5 U.S... for which the FEHB Program premiums for the contract term will be less than the threshold at FAR 15...

  6. 48 CFR 22.1003-1 - General.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... PROGRAMS APPLICATION OF LABOR LAWS TO GOVERNMENT ACQUISITIONS Service Contract Act of 1965, as Amended 22.1003-1 General. This subpart 22.10 applies to all Government contracts, the principal purpose of which... does not apply to individual contract requirements for services in contracts not having as their...

  7. Yacht type and crew-specific differences in anthropometric, aerobic capacity, and muscle strength parameters among international Olympic class sailors.

    PubMed

    Bojsen-Møller, Jens; Larsson, Benny; Magnusson, S Peter; Aagaard, Per

    2007-08-01

    Physical fitness and muscular strength are important performance factors for Olympic class sailors, but the physical demands vary greatly between yacht classes, and limited information is available regarding the physical demands for the different crew positions. In the present paper, strength and aerobic capacity data from elite Olympic sailors are presented and compared with previous findings. Furthermore, a system for classification of Olympic class sailors is suggested. Peak aerobic capacity (peak oxygen uptake, VO(2peak)) and maximal isometric and isokinetic muscle strength of the knee extensors and flexors were assessed, together with the hamstring/quadriceps strength ratio (H/Q ratio). Peak aerobic capacity (ml O(2) . min(-1) . kg(-2/3)) was as follows: males - static hikers (n = 5) 215, s = 7; dynamic hikers (n = 8) 252, s = 17; trapezing helmsmen (n = 6) 234, s = 15; trapezing crew (n = 10) 239, s = 16; females - dynamic hikers (n = 6) 194, s = 16; trapezing crew (n = 2) 200, s = 13. Strength data for hikers, presented as peak moments (normalized to body weight) obtained during eccentric, isometric, and concentric contraction (Nm . kg(-1)) respectively were as follows: males - quadriceps: 3.66 (s = 0.68), 3.97 (s = 0.66), 1.82 (s = 0.34); hamstrings: 1.93 (s = 0.22), 1.38 (s = 0.41), 1.05 (s = 0.21); females - quadriceps: 3.84 (s = 0.71), 3.81 (s = 0.58), 1.60 (s = 0.28); hamstrings: 1.75 (s = 0.23), 1.10 (s = 0.16), 0.84 (s = 0.13). The peak moment based H/Q ratios for slow eccentric and concentric contractions were 0.42 (s = 0.11) and 0.39 (s = 0.04) for males and 0.43 (s = 0.06) and 0.39 (s = 0.04) for females respectively. Elite Olympic class sailors demonstrated high VO(2peak) values comparable to those observed in other non-endurance sports. The strength data revealed very high quadriceps strength for hikers, which is likely a result of the high muscle forces encountered during sailing, and a low H/Q ratio. To ensure optimal knee joint stabilization during sailing and other training activities, it is suggested that hikers should counter this strength imbalance by performing additional strength training for the hamstrings muscle group.

  8. Studies of Verbal Problem Solving. 1. Two Performance-Aiding Programs

    DTIC Science & Technology

    1977-09-01

    5. Effective Date of Contract 6. Contract Expiration Date 7. Amount of Contract 8. Contract Number 9. Principal Investigator 10 . Scientific...7 10 3. A Mystery Solved by Propositional Calculus 16 1v I. INTRODUCTION Certain intellectual tasks, such as estimating and combining prob...aids or without any special training, they get the right answer within 15 minutes or so (about 80% of one large psychology class solved it). A few

  9. Program on the combustion chemistry of low- and intermediate-Btu gas mixtures

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1981-11-30

    Low and intermediate Btu (LBTU and IBTU) gas mixtures are essentially mixtures of CO, H/sub 2/ and CH/sub 4/ diluted with nitrogen and CO/sub 2/. Although the combustion properties of these three fuels have been extensively investigated and their individual combustion kinetics are reasonably well established, prediction techniques for applying these gas mixtures remain for the most part empirical. This program has aimed to bring together and apply some of the fundamental combustion parameters to the CO-H/sub 2/-CH/sub 4/ flame system with the hope of reducing some of this empiricism. Four topical reports have resulted from this program. This finalmore » report summarizes these reports and other activities undertaken in this program. This program was initiated June 22, 1976 under ERDA Contract No. E(49-18)-2406 and was later continued under DOE/PETC and DOE Contract No. DE-AC22-76ET10653.« less

  10. Handbook of Phase Transition Sulfides, Selenides and Tellurides,

    DTIC Science & Technology

    1984-07-01

    guidance and control. The Contracting Officer is Mrs. S. Williams, DESC, Dayton, Ohio. The Contracting Officers Technical Representative is Mr. H . C...higher temperature phase change where AgGaS2 becomes metallic. REFERENCES (AgGaS2 ) 1. H . Hahn, et.al., Z. Anorg. Chem., 271, 153 (1953). 2. M.V. Hobden...Phys. Soc. Japan, Vol. 23, 37 (1967). 10. H.H. Dorner, H.P. Geserich, and H . Rickert, Phys. Stat. Sol. (a), Vol. 37, K85 (1970). 11. P. Bruesch and J

  11. The Role of Frame Force in Quantum Detection

    DTIC Science & Technology

    2007-01-01

    42040) 10. C. H. Bennett, Quantum cryptography using any two nonorthogonal states, Phys. Rev. Lett. 68 (1992), no. 21, 3121–3124. MR 1 163 546 11. S ...SUBTITLE The Role of Frame Force in Quantum Detection 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR( S ) 5d. PROJECT...equivalent to a quantum detection problem from quantum mechanics. To this end we first reformulate Problem 1.2 in terms of orthonormal bases instead of 1

  12. 48 CFR 570.308 - Award.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Award. 570.308 Section 570.308 Federal Acquisition Regulations System GENERAL SERVICES ADMINISTRATION SPECIAL CONTRACTING PROGRAMS ACQUIRING LEASEHOLD INTERESTS IN REAL PROPERTY Contracting Procedures for Leasehold Interests in...

  13. 48 CFR 1823.1005 - Contract clause.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 6 2013-10-01 2013-10-01 false Contract clause. 1823.1005 Section 1823.1005 Federal Acquisition Regulations System NATIONAL AERONAUTICS AND SPACE ADMINISTRATION SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY TECHNOLOGIES, OCCUPATIONAL...

  14. 47 CFR 76.108 - Indemnification contracts.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 4 2011-10-01 2011-10-01 false Indemnification contracts. 76.108 Section 76.108 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) BROADCAST RADIO SERVICES... indemnify a cable system for liability resulting from failure to delete programming in accordance with the...

  15. 47 CFR 76.108 - Indemnification contracts.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 4 2010-10-01 2010-10-01 false Indemnification contracts. 76.108 Section 76.108 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) BROADCAST RADIO SERVICES... indemnify a cable system for liability resulting from failure to delete programming in accordance with the...

  16. 48 CFR 1823.7101 - Contract clause.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 6 2014-10-01 2014-10-01 false Contract clause. 1823.7101 Section 1823.7101 Federal Acquisition Regulations System NATIONAL AERONAUTICS AND SPACE ADMINISTRATION SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY TECHNOLOGIES, OCCUPATIONAL...

  17. 48 CFR 1823.1005 - Contract clause.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 6 2014-10-01 2014-10-01 false Contract clause. 1823.1005 Section 1823.1005 Federal Acquisition Regulations System NATIONAL AERONAUTICS AND SPACE ADMINISTRATION SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY TECHNOLOGIES, OCCUPATIONAL...

  18. 48 CFR 1823.1005 - Contract clause.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 6 2012-10-01 2012-10-01 false Contract clause. 1823.1005 Section 1823.1005 Federal Acquisition Regulations System NATIONAL AERONAUTICS AND SPACE ADMINISTRATION SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY TECHNOLOGIES, OCCUPATIONAL...

  19. 48 CFR 1823.7101 - Contract clause.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 6 2012-10-01 2012-10-01 false Contract clause. 1823.7101 Section 1823.7101 Federal Acquisition Regulations System NATIONAL AERONAUTICS AND SPACE ADMINISTRATION SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY TECHNOLOGIES, OCCUPATIONAL...

  20. 48 CFR 23.303 - Contract clause.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 1 2013-10-01 2013-10-01 false Contract clause. 23.303 Section 23.303 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY TECHNOLOGIES, OCCUPATIONAL SAFETY, AND...

  1. 48 CFR 223.303 - Contract clause.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Contract clause. 223.303 Section 223.303 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY...

  2. 48 CFR 23.804 - Contract clauses.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 1 2012-10-01 2012-10-01 false Contract clauses. 23.804 Section 23.804 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY TECHNOLOGIES, OCCUPATIONAL SAFETY, AND...

  3. 48 CFR 223.7203 - Contract clause.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Contract clause. 223.7203 Section 223.7203 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY...

  4. 48 CFR 23.1005 - Contract clause.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 1 2013-10-01 2013-10-01 false Contract clause. 23.1005 Section 23.1005 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY TECHNOLOGIES, OCCUPATIONAL SAFETY, AND...

  5. 48 CFR 223.7203 - Contract clause.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Contract clause. 223.7203 Section 223.7203 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY...

  6. 48 CFR 223.7106 - Contract clause.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Contract clause. 223.7106 Section 223.7106 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY...

  7. 48 CFR 23.303 - Contract clause.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 1 2012-10-01 2012-10-01 false Contract clause. 23.303 Section 23.303 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY TECHNOLOGIES, OCCUPATIONAL SAFETY, AND...

  8. 48 CFR 1223.303 - Contract clause.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Contract clause. 1223.303 Section 1223.303 Federal Acquisition Regulations System DEPARTMENT OF TRANSPORTATION SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY TECHNOLOGIES, OCCUPATIONAL SAFETY, AND...

  9. 48 CFR 23.903 - Contract clause.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 1 2012-10-01 2012-10-01 false Contract clause. 23.903 Section 23.903 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY TECHNOLOGIES, OCCUPATIONAL SAFETY, AND...

  10. 48 CFR 223.7103 - Contract clause.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Contract clause. 223.7103 Section 223.7103 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY...

  11. 48 CFR 223.303 - Contract clause.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Contract clause. 223.303 Section 223.303 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY...

  12. 48 CFR 23.303 - Contract clause.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Contract clause. 23.303 Section 23.303 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY TECHNOLOGIES, OCCUPATIONAL SAFETY, AND...

  13. 48 CFR 23.1005 - Contract clause.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 1 2012-10-01 2012-10-01 false Contract clause. 23.1005 Section 23.1005 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY TECHNOLOGIES, OCCUPATIONAL SAFETY, AND...

  14. 48 CFR 223.7306 - Contract clause.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Contract clause. 223.7306 Section 223.7306 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY...

  15. 48 CFR 223.7306 - Contract clause.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Contract clause. 223.7306 Section 223.7306 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY...

  16. 48 CFR 223.303 - Contract clause.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Contract clause. 223.303 Section 223.303 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY...

  17. 48 CFR 223.7103 - Contract clause.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Contract clause. 223.7103 Section 223.7103 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY...

  18. 48 CFR 223.303 - Contract clause.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Contract clause. 223.303 Section 223.303 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY...

  19. 48 CFR 23.1105 - Contract clause.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 1 2013-10-01 2013-10-01 false Contract clause. 23.1105 Section 23.1105 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY TECHNOLOGIES, OCCUPATIONAL SAFETY, AND...

  20. 48 CFR 223.7203 - Contract clause.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Contract clause. 223.7203 Section 223.7203 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY...

  1. 48 CFR 1223.303 - Contract clause.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 5 2014-10-01 2014-10-01 false Contract clause. 1223.303 Section 1223.303 Federal Acquisition Regulations System DEPARTMENT OF TRANSPORTATION SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY TECHNOLOGIES, OCCUPATIONAL SAFETY, AND...

  2. 48 CFR 1223.303 - Contract clause.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 5 2013-10-01 2013-10-01 false Contract clause. 1223.303 Section 1223.303 Federal Acquisition Regulations System DEPARTMENT OF TRANSPORTATION SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY TECHNOLOGIES, OCCUPATIONAL SAFETY, AND...

  3. 48 CFR 1523.303 - Contract clause.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Contract clause. 1523.303 Section 1523.303 Federal Acquisition Regulations System ENVIRONMENTAL PROTECTION AGENCY SOCIOECONOMIC PROGRAMS ENVIRONMENTAL, CONSERVATION, OCCUPATIONAL SAFETY, AND DRUG-FREE WORKPLACE Hazardous Material and...

  4. Effects of multidimensional pelvic floor muscle training in healthy young women.

    PubMed

    Talasz, Helena; Kalchschmid, Elisabeth; Kofler, Markus; Lechleitner, Monika

    2012-03-01

    Cross-sectional and interventional study to assess pelvic floor muscle (PFM) function in healthy young nulliparous women and to determine the effects of a 3-month PFM training program with emphasis on co-contraction of PFM and anterolateral abdominal muscles and on correctly performed coughing patterns. PFM function was assessed by digital vaginal palpation in 40 volunteers and graded according to the 6-point Oxford grading scale. The PFM training program was comprised theoretical instruction, as well as verbal feedback during hands-on instruction and repeated training sessions focussing on strengthening PFM and anterolateral abdominal muscle co-contraction during forced expiration and coughing. At baseline, 30 women (75%) were able to perform normal PFM contractions at rest (Oxford scale score ≥ 3); only 4 of them (10%) presented additional involuntary PFM contractions before and during coughing. The remaining 10 women (25%) were unable to perform voluntary or involuntary PFM contractions. Mean Oxford scale score in the whole group was 3.3 ± 1.7. After completing the PFM training program, 29 women (72.5%) performed cough-related PFM contractions and group mean Oxford scale score increased significantly to 4.2 ± 1.0. The study shows that PFM dysfunction may be detected even in healthy young women. Multidimensional training, however, may significantly improve PFM function.

  5. Activation of plantar flexor muscles is constrained by multiple muscle synergies rather than joint torques

    PubMed Central

    Suzuki, Takahito; Kinugasa, Ryuta; Fukashiro, Senshi

    2017-01-01

    Behavioral evidence has suggested that a small number of muscle synergies may be responsible for activating a variety of muscles. Nevertheless, such dimensionality reduction may also be explained using the perspective of alternative hypotheses, such as predictions based on linear combinations of joint torques multiplied by corresponding coefficients. To compare the explanatory capacity of these hypotheses for describing muscle activation, we enrolled 12 male volunteers who performed isometric plantar flexor contractions at 10–100% of maximum effort. During each plantar flexor contraction, the knee extensor muscles were isometrically contracted at 0%, 50%, or 100% of maximum effort. Electromyographic activity was recorded from the vastus lateralis, medial gastrocnemius (MG), lateral gastrocnemius (LG), and soleus muscles and quantified using the average rectified value (ARV). At lower plantar flexion torque, regression analysis identified a clear linear relationship between the MG and soleus ARVs and between the MG and LG ARVs, suggesting the presence of muscle synergy (r2 > 0.65). The contraction of the knee extensor muscles induced a significant change in the slope of this relationship for both pairs of muscles (MG × soleus, P = 0.002; MG × LG, P = 0.006). Similarly, the slope of the linear relationship between the plantar flexion torque and the ARV of the MG or soleus changed significantly with knee extensor contraction (P = 0.031 and P = 0.041, respectively). These results suggest that muscle synergies characterized by non-mechanical constraints are selectively recruited according to whether contraction of the knee extensor muscles is performed simultaneously, which is relatively consistent with the muscle synergy hypothesis. PMID:29107958

  6. Evidence for P(2)-purinoceptors contribution in H(2)O(2)-induced contraction of rat aorta in the absence of endothelium.

    PubMed

    Shen, J Z; Zheng, X F; Kwan, C Y

    2000-08-18

    H(2)O(2) can contract many arteries, however the underlying mechanisms are not fully understood. This study aims to test whether H(2)O(2)-induced vasoconstriction could be functionally attributed to the activation of P(2)-purinoceptors in rat aorta and to explore its possible signaling mechanisms. Isometric tension recording of H(2)O(2) and ATP-induced contractions of rat aortic rings were compared in the absence or presence of various pharmacological tools to identify their possible common signaling pathways. Both H(2)O(2) and ATP induced transient phasic contractions in a concentration-dependent manner (1-1000 microM). Removal of endothelium potentiated the contractile responses to H(2)O(2) and to ATP. H(2)O(2) (30 microM)-induced phasic contraction could be abolished by catalase (800 U/ml), but not affected by SOD (150 U/ml), DMSO (5 mM) and apyrase (5 U/ml), suggesting no involvement of O(2)(-), hydroxyl free radicals and ATP release. Also, several receptor antagonists including phentolamine, atropine, methysergide and chlorpheniramine (each 3 microM) were without effect on H(2)O(2) (30 microM)-induced phasic contraction, suggesting no involvement of typical neurotransmitter release. However, both H(2)O(2) (30 microM) and ATP (1 mM)-induced phasic contractions not only presented homologous desensitization, but also showed heterogeneous desensitization. Furthermore, the phasic contractions in response to H(2)O(2) (30 microM) or ATP (100 microM) could be inhibited or abolished in a concentration dependent manner by RB-2 and suramin (10-100 microM), two widely used P(2)-purinoceptor antagonists, with only partial inhibition by Evans blue (300 microM), a moderately selective P(2x) receptor blocker, or by alpha-beta-methylene-ATP (100 microM), a selective P(2x) receptor desensitizer. On the other hand, both H(2)O(2) (30 microM) and ATP (100 microM)-induced phasic contractions were also attenuated, to different degree, by inhibitors of several enzymes including PLC, PKC, PLA(2) and cyclooxygenase. Lastly, removal of extracellular Ca(2+) or pretreatment with procaine (10 mM) and dantrolene (30 microM), two putative intracellular Ca(2+) release blockers, or with Ni(2+) (100 microM) and tetrandrine (5 microM), two Ca(2+) channel blockers, all significantly inhibited H(2)O(2) and ATP-induced contractions. However, nifedipine (1 microM), a voltage-dependent L-type Ca(2+) channel blocker, was without effect. Our results demonstrate that H(2)O(2)-induced phasic contraction of rat aorta involves, at least in part, the activation of P(2)-purinoceptors in the aortic smooth muscle cells

  7. Effect of Fructus Psoraleae on motility of gallbladder isolated smooth muscle strips from guinea pigs

    PubMed Central

    Jin, Shan; Li, Mei; Lin, Mei-Ling; Ding, Yong-Hui; Qu, Song-Yi; Li, Wei; Zheng, Tian-Zhen

    2006-01-01

    AIM: To observe the effect of Fructus Psoraleae on motility of isolated gallbladder muscle strips of guinea pigs and its mechanism. METHODS: Guinea pigs were hit to lose consciousness and the whole gallbladder was removed quickly. Two or three smooth muscle strips (8 mm × 3 mm) were cut along a longitudinal direction. The mucosa was gently removed. Every longitudinal muscle strip was suspended in a tissue chamber which was continuously perfused with 5 mL Krebs solution (37°C), pH 7.4, and aerated with 950 mL/L O2 and 50 mL /L CO2. The isometric response was recorded with an ink-writing recorder. After 2 h equilibration under 1 g-load, 50 μL Fructus Psoraleae (10, 20, 70, 200, 700, 1000 g/L) was added cumulatively into the tissue chamber in turn every 2 min to observe their effects on gallbladder muscle strips (cumulating final concentration of Fructus Psoraleae was 0.1, 0.3, 1.0, 3.0, 10.0, 20.0 g/L). The antagonists, including 4-DAMP, benzhydramine, hexamethonium, phentolamine, verapamil and idomethine were given 2 min before Fructus Psoraleae respectively to investigate the mechanisms involved. RESULTS: Fructus Psoraleae dose-dependently increased the resting tension (r = 0.992, P < 0.001), decreased the mean contractile amplitude (r = 0.970, P < 0.001) and meanwhile increased the contractile frequency of the gallbladder muscle strip in vitro (r = 0.965, P < 0.001). The exciting action of Fructus Psoraleae on the resting tension could be partially blocked by 4-DAMP (the resting tension decreased from 1.37 ± 0.41 to 0.70 ± 0.35, P < 0.001), benzhydramine (from 1.37 ± 0.41 to 0.45 ± 0.38, P < 0.001), hexamethonium (from 1.37 ± 0.41 to 0.94 ± 0.23, P < 0.05), phentolamine ( from 1.37 ± 0.41 to 0.89 ± 0.22, P < 0.01) and verapamil (from 1.37 ± 0.41 to 0.94 ± 0.26, P < 0.05). But the above antagonists had no significant effect on the action of Fructus Psoraleae–induced mean contractile amplitude (P > 0.05). Moreover, the increase of the contractile frequency due to Fructus Psoraleae was inhibited by 4-DAMP (decreased from 8.3 ± 1.2 to 6.8 ± 0.5, P < 0.01) and hexamethonium (from 8.3 ± 1.2 to 7.0 ± 0.9, P < 0.05). Idomethine had no significant effect on the Fructus Psoraleae-induced responses (P > 0.05). CONCLUSION: Fructus Psoraleae enhances the motility of isolated gallbladder muscle strips from guinea pigs, in a dose-dependent manner. The effect of Fructus Psoraleae is partly related to M3, N receptor, α receptor, H1 receptor, Ca2+ channel, but not related to prostaglandin. PMID:16937536

  8. 7 CFR 1410.53 - Executed CRP contract not in conformity with regulations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Executed CRP contract not in conformity with... RESERVE PROGRAM § 1410.53 Executed CRP contract not in conformity with regulations. If, after a CRP contract is approved by CCC, it is discovered that such CRP contract is found to contain material errors of...

  9. 7 CFR 1942.18 - Community facilities-Planning, bidding, contracting, constructing.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Poisoning and Prevention Act of 1971 (42 U.S.C. 4801) and the National Consumer Health Information and... (Government Printing Office stock No. 041-001-00187-5) as prepared by the Federal Coordinating Council for Science, Engineering and Technology. (14) Pipe. All pipe used shall meet current American Society for...

  10. Milk-deteriorating exoenzymes from Pseudomonas fluorescens 041 isolated from refrigerated raw milk.

    PubMed

    Martins, Maurilio L; Pinto, Uelinton M; Riedel, Katharina; Vanetti, Maria C D

    2015-03-01

    The practice of refrigerating raw milk at the farm has provided a selective advantage for psychrotrophic bacteria that produce heat-stable proteases and lipases causing severe quality problems to the dairy industry. In this work, a protease (AprX) and a lipase (LipM) produced by Pseudomonas fluorescens 041, a highly proteolytic and lipolytic strain isolated from raw milk obtained from a Brazilian farm, have been purified and characterized. Both enzymes were purified as recombinant proteins from Escherichia coli . The AprX metalloprotease exhibited activity in a broad temperature range, including refrigeration, with a maximum activity at 37 °C. It was active in a pH range of 4.0 to 9.0. This protease had maximum activity with the substrates casein and gelatin in the presence of Ca (+2) . The LipM lipase had a maximum activity at 25 °C and a broad pH optimum ranging from 7.0 to 10. It exhibited the highest activity, in the presence of Ca (+2) , on substrates with long-chain fatty acid residues. These results confirm the spoilage potential of strain 041 in milk due to, at least in part, these two enzymes. The work highlights the importance of studies of this kind with strains isolated in Brazil, which has a recent history on the implementation of the cold chain at the dairy farm.

  11. 48 CFR 923.903 - Contract clause.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 5 2014-10-01 2014-10-01 false Contract clause. 923.903 Section 923.903 Federal Acquisition Regulations System DEPARTMENT OF ENERGY SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY TECHNOLOGIES, OCCUPATIONAL SAFETY, AND DRUG-FREE...

  12. 48 CFR 923.903 - Contract clause.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 5 2012-10-01 2012-10-01 false Contract clause. 923.903 Section 923.903 Federal Acquisition Regulations System DEPARTMENT OF ENERGY SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY TECHNOLOGIES, OCCUPATIONAL SAFETY, AND DRUG-FREE...

  13. 48 CFR 923.903 - Contract clause.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Contract clause. 923.903 Section 923.903 Federal Acquisition Regulations System DEPARTMENT OF ENERGY SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY TECHNOLOGIES, OCCUPATIONAL SAFETY, AND DRUG-FREE...

  14. 48 CFR 923.903 - Contract clause.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 5 2013-10-01 2013-10-01 false Contract clause. 923.903 Section 923.903 Federal Acquisition Regulations System DEPARTMENT OF ENERGY SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY TECHNOLOGIES, OCCUPATIONAL SAFETY, AND DRUG-FREE...

  15. 47 CFR 76.125 - Indemnification contracts.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 4 2011-10-01 2011-10-01 false Indemnification contracts. 76.125 Section 76.125 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) BROADCAST RADIO SERVICES... programming in accordance with the provisions of this Subpart unless the licensee has a reasonable basis for...

  16. 47 CFR 76.125 - Indemnification contracts.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 4 2010-10-01 2010-10-01 false Indemnification contracts. 76.125 Section 76.125 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) BROADCAST RADIO SERVICES... programming in accordance with the provisions of this Subpart unless the licensee has a reasonable basis for...

  17. 48 CFR 2115.070 - Negotiation authority.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Negotiation authority. 2115.070 Section 2115.070 Federal Acquisition Regulations System OFFICE OF PERSONNEL MANAGEMENT, FEDERAL... CONTRACTING BY NEGOTIATION 2115.070 Negotiation authority. The authority to negotiate FEGLI Program contracts...

  18. 48 CFR 23.406 - Solicitation provisions and contract clauses.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 1 2013-10-01 2013-10-01 false Solicitation provisions and contract clauses. 23.406 Section 23.406 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY TECHNOLOGIES...

  19. 48 CFR 1823.570-2 - Contract clause.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 6 2014-10-01 2014-10-01 false Contract clause. 1823.570-2 Section 1823.570-2 Federal Acquisition Regulations System NATIONAL AERONAUTICS AND SPACE ADMINISTRATION SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY TECHNOLOGIES...

  20. 48 CFR 1823.570-2 - Contract clause.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 6 2012-10-01 2012-10-01 false Contract clause. 1823.570-2 Section 1823.570-2 Federal Acquisition Regulations System NATIONAL AERONAUTICS AND SPACE ADMINISTRATION SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY TECHNOLOGIES...

  1. 48 CFR 23.406 - Solicitation provisions and contract clauses.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Solicitation provisions and contract clauses. 23.406 Section 23.406 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY TECHNOLOGIES...

  2. 48 CFR 223.370-5 - Contract clauses.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Contract clauses. 223.370-5 Section 223.370-5 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY...

  3. 48 CFR 223.370-5 - Contract clauses.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Contract clauses. 223.370-5 Section 223.370-5 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY...

  4. 48 CFR 223.370-5 - Contract clauses.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Contract clauses. 223.370-5 Section 223.370-5 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY...

  5. 48 CFR 23.406 - Solicitation provisions and contract clauses.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 1 2012-10-01 2012-10-01 false Solicitation provisions and contract clauses. 23.406 Section 23.406 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY TECHNOLOGIES...

  6. 50 CFR 81.12 - Contracts.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 50 Wildlife and Fisheries 6 2010-10-01 2010-10-01 false Contracts. 81.12 Section 81.12 Wildlife and Fisheries UNITED STATES FISH AND WILDLIFE SERVICE, DEPARTMENT OF THE INTERIOR (CONTINUED) FINANCIAL ASSISTANCE-WILDLIFE SPORT FISH RESTORATION PROGRAM CONSERVATION OF ENDANGERED AND THREATENED...

  7. 41 CFR 51-10.149 - Program accessibility: Discrimination prohibited.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Relating to Public Contracts COMMITTEE FOR PURCHASE FROM PEOPLE WHO ARE BLIND OR SEVERELY DISABLED 10... FOR PURCHASE FROM PEOPLE WHO ARE BLIND OR SEVERELY DISABLED § 51-10.149 Program accessibility...

  8. 41 CFR 51-10.150 - Program accessibility: Existing facilities.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Relating to Public Contracts COMMITTEE FOR PURCHASE FROM PEOPLE WHO ARE BLIND OR SEVERELY DISABLED 10... FOR PURCHASE FROM PEOPLE WHO ARE BLIND OR SEVERELY DISABLED § 51-10.150 Program accessibility...

  9. 41 CFR 51-10.149 - Program accessibility: Discrimination prohibited.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Relating to Public Contracts COMMITTEE FOR PURCHASE FROM PEOPLE WHO ARE BLIND OR SEVERELY DISABLED 10... FOR PURCHASE FROM PEOPLE WHO ARE BLIND OR SEVERELY DISABLED § 51-10.149 Program accessibility...

  10. 41 CFR 51-10.150 - Program accessibility: Existing facilities.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Relating to Public Contracts COMMITTEE FOR PURCHASE FROM PEOPLE WHO ARE BLIND OR SEVERELY DISABLED 10... FOR PURCHASE FROM PEOPLE WHO ARE BLIND OR SEVERELY DISABLED § 51-10.150 Program accessibility...

  11. 41 CFR 51-10.149 - Program accessibility: Discrimination prohibited.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Relating to Public Contracts COMMITTEE FOR PURCHASE FROM PEOPLE WHO ARE BLIND OR SEVERELY DISABLED 10... FOR PURCHASE FROM PEOPLE WHO ARE BLIND OR SEVERELY DISABLED § 51-10.149 Program accessibility...

  12. 41 CFR 51-10.149 - Program accessibility: Discrimination prohibited.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Relating to Public Contracts COMMITTEE FOR PURCHASE FROM PEOPLE WHO ARE BLIND OR SEVERELY DISABLED 10... FOR PURCHASE FROM PEOPLE WHO ARE BLIND OR SEVERELY DISABLED § 51-10.149 Program accessibility...

  13. 41 CFR 51-10.150 - Program accessibility: Existing facilities.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Relating to Public Contracts COMMITTEE FOR PURCHASE FROM PEOPLE WHO ARE BLIND OR SEVERELY DISABLED 10... FOR PURCHASE FROM PEOPLE WHO ARE BLIND OR SEVERELY DISABLED § 51-10.150 Program accessibility...

  14. 48 CFR 970.1907 - The Small Business Subcontracting Program.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 5 2014-10-01 2014-10-01 false The Small Business... AGENCY SUPPLEMENTARY REGULATIONS DOE MANAGEMENT AND OPERATING CONTRACTS Small Business Programs 970.1907 The Small Business Subcontracting Program. ...

  15. 48 CFR 970.1907 - The Small Business Subcontracting Program.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 5 2013-10-01 2013-10-01 false The Small Business... AGENCY SUPPLEMENTARY REGULATIONS DOE MANAGEMENT AND OPERATING CONTRACTS Small Business Programs 970.1907 The Small Business Subcontracting Program. ...

  16. 48 CFR 970.1907 - The Small Business Subcontracting Program.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 5 2012-10-01 2012-10-01 false The Small Business... AGENCY SUPPLEMENTARY REGULATIONS DOE MANAGEMENT AND OPERATING CONTRACTS Small Business Programs 970.1907 The Small Business Subcontracting Program. ...

  17. 48 CFR 970.1907 - The Small Business Subcontracting Program.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false The Small Business... AGENCY SUPPLEMENTARY REGULATIONS DOE MANAGEMENT AND OPERATING CONTRACTS Small Business Programs 970.1907 The Small Business Subcontracting Program. ...

  18. 48 CFR 212.7002 - Pilot program.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Pilot program. 212.7002... OF DEFENSE ACQUISITION PLANNING ACQUISITION OF COMMERCIAL ITEMS Pilot Program for Transition to Follow-On Contracting After Use of Other Transaction Authority 212.7002 Pilot program. ...

  19. 48 CFR 212.7002 - Pilot program.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Pilot program. 212.7002... OF DEFENSE ACQUISITION PLANNING ACQUISITION OF COMMERCIAL ITEMS Pilot Program for Transition to Follow-On Contracting After Use of Other Transaction Authority 212.7002 Pilot program. ...

  20. A Pilates exercise program with pelvic floor muscle contraction: Is it effective for pregnant women? A randomized controlled trial.

    PubMed

    Dias, Naiara T; Ferreira, Letícia R; Fernandes, Mariana G; Resende, Ana Paula M; Pereira-Baldon, Vanessa S

    2018-01-01

    The aim of this study was to evaluate the effectiveness of a Pilates exercise program with pelvic floor muscle (PFM) contraction compared to a conventional intervention in pregnant women. Fifty primiparous women, without gestational alterations, were randomized to the Pilates group (n = 25) and control group (n = 25). Interventions for both groups consisted of twice-weekly sessions of 1 h each during the period between the 14-16th and 32-34th gestational weeks. The Pilates group performed a Pilates exercises program with the addition of voluntary PFM contraction. Mat-based Pilates exercises were performed involving movement of the upper limbs, lower limbs and trunk in all sessions. The Control group walked for 10 min and performed strengthening exercises of the lower limbs, upper limbs, and trunk with resistance from an elastic band and body weight. Each woman was evaluated by an unblinded physiotherapist before and after intervention for primary (PFM strength using a manometer) and secondary (PFM strength using Oxford Scale, endurance and repeatability) outcomes. Covariance analysis (ANCOVA) was used to compare the groups using the baseline values as a covariate. Thirty-six women were included in the analysis. There were no differences between the groups for manometry. An increase in the PFM strength, endurance, and repeatability was only observed in the Pilates group. In addition, the Pilates group showed greater adherence to the intervention. Pilates exercise program with PFM contraction is not able to change the PFM strength assessed by manometer in pregnant women, but it improved adherence to the intervention. © 2017 Wiley Periodicals, Inc.

  1. Lightweight, high-frequency transformers

    NASA Technical Reports Server (NTRS)

    Schwarze, G. E.

    1983-01-01

    The 25-kVA space transformer was developed under contract by Thermal Technology Laboratory, Buffalo, N. Y. The NASA Lewis transformer technology program attempted to develop the baseline technology. For the 25-kVA transformer the input voltage was chosen as 200 V, the output voltage as 1500 V, the input voltage waveform as square wave, the duty cycle as continuous, the frequency range (within certain constraints) as 10 to 40 kHz, the operating temperatures as 85 deg. and 130 C, the baseplate temperature as 50 C, the equivalent leakage inductance as less than 10 micro-h, the operating environment as space, and the life expectancy as 10 years. Such a transformer can also be used for aircraft, ship and terrestrial applications.

  2. 48 CFR 570.303-4 - Changes to SFOs.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Changes to SFOs. 570.303-4 Section 570.303-4 Federal Acquisition Regulations System GENERAL SERVICES ADMINISTRATION SPECIAL CONTRACTING PROGRAMS ACQUIRING LEASEHOLD INTERESTS IN REAL PROPERTY Contracting Procedures for Leasehold...

  3. 48 CFR 570.303-1 - Preparing the SFO.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Preparing the SFO. 570.303-1 Section 570.303-1 Federal Acquisition Regulations System GENERAL SERVICES ADMINISTRATION SPECIAL CONTRACTING PROGRAMS ACQUIRING LEASEHOLD INTERESTS IN REAL PROPERTY Contracting Procedures for Leasehold...

  4. 48 CFR 570.303-2 - Issuing the SFO.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Issuing the SFO. 570.303-2 Section 570.303-2 Federal Acquisition Regulations System GENERAL SERVICES ADMINISTRATION SPECIAL CONTRACTING PROGRAMS ACQUIRING LEASEHOLD INTERESTS IN REAL PROPERTY Contracting Procedures for Leasehold...

  5. 48 CFR 2422.1408 - Contract clause.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Contract clause. 2422.1408 Section 2422.1408 Federal Acquisition Regulations System DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT SOCIOECONOMIC PROGRAMS APPLICATION OF LABOR LAWS TO GOVERNMENT ACQUISITIONS Employment of the Handicapped 2422...

  6. 48 CFR 25.504 - Evaluation Examples.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... PROGRAMS FOREIGN ACQUISITION Evaluating Foreign Offers-Supply Contracts 25.504 Evaluation Examples. The... examples assume that the contracting officer has eliminated all offers that are unacceptable for reasons... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Evaluation Examples. 25...

  7. 48 CFR 323.7002 - Actions required.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Actions required. 323.7002 Section 323.7002 Federal Acquisition Regulations System HEALTH AND HUMAN SERVICES SOCIOECONOMIC PROGRAMS... WORKPLACE Safety and Health 323.7002 Actions required. (a) Contracting activities. The Contracting Officer...

  8. 42 CFR 52h.1 - Applicability.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Applicability. 52h.1 Section 52h.1 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS SCIENTIFIC PEER REVIEW OF RESEARCH GRANT APPLICATIONS AND RESEARCH AND DEVELOPMENT CONTRACT PROJECTS § 52h.1 Applicability. (a) This part...

  9. Effects of ankle joint position and submaximal muscle contraction intensity on soleus H-reflex modulation in young and older adults.

    PubMed

    Chen, Yung-Sheng; Zhou, Shi; Cartwright, Colleen

    2014-04-01

    This study investigated the effects of ankle joint position and submaximal contraction intensity on soleus (SOL) H-reflex modulation. Twenty young (25.1 ± 4.8 years) and 20 older adults (74.2 ± 5.1 years) performed plantar flexions during 10%, 30% and 50% maximal voluntary contractions (MVC) and at ankle positions of neutral (0°), plantar flexion (20°) and dorsiflexion (-20°) in a sitting position. The SOL H-reflex gain in older adults was relatively lower than that in young adults during 10%, 30% and 50% MVC. The SOL H-reflex gain was significantly affected by the intensity of plantar flexion in the respective ankle joint position in both age groups. The latency of H-reflex was prolonged in older adults and was ankle joint dependent in young adults. Young adults demonstrated a shorter duration of the H-reflex response than that of older adults. The results indicated that there were age-related changes in the SOL H-reflex during the ankle plantar flexors activities.

  10. Contraction induced h reflexes in the diagnosis of cervical radiculopathy.

    PubMed

    Bodofsky, Elliot B; Campellone, Joseph V; Cohen, Stephen J; Caten, Holly N; Schindelheim, Adam M

    2015-06-01

    To determine whether Contraction Induced H Reflexes (CIHR) can accurately detect cervical radiculopathy. Comparison of CIHR results with Needle Electromyography at academic outpatient Electromyography/Nerve Conduction laboratories. Participants were all patients over 18 with a needle electromyography diagnosis of cervical radiculopathy. Patients were tested for CIHR in at least two upper extremity muscles in electromyographically proven myotomes bilaterally. Patients were requested to perform a moderate contraction while stimulus was applied proximally (elbow or Erb's point). Outcome measures included H Reflex onset latency and side-to-side latency differences. These were compared against previously established normal values. Overall, 10 of 15 patients who met criteria for cervical radiculopathy showed CIHR abnormalities (sensitivity = 67%; 95% confidence interval, 43-91). Counting each side and level separately, CIHR identified 16/27 radiculopathies (sensitivity = 59.2%; 95% confidence interval, 40.6-77.8). Contraction Induced H Reflexes identified 1 possible radiculopathy not seen on electromyography (specificity = 98%; 95% confidence interval, 95-100). Contraction induced H Reflexes have a sensitivity and specificity for cervical radiculopathy similar to the resting Gastroc-Soleus H Reflex.

  11. 48 CFR 923.103 - Contract clauses.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... ENVIRONMENT, CONSERVATION, OCCUPATIONAL SAFETY, AND DRUG-FREE WORKPLACE Sustainable Acquisition 923.103... Construction Contracts; FAR 52.223-10, Waste Reduction Program; FAR 52.223-XX, Compliance with Environmental...

  12. A Female Urinary Diversion Device for Military Women in the Deployed Environment

    DTIC Science & Technology

    2016-10-27

    9. SPONSORING / MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10. SPONSOR/MONITOR’S ACRONYM(S) TriService Nursing Research TSNRP Program, 4301 Jones...reported there were many opportunities for a FUDD due to unsanitary and challenging conditions. Implications for Military Nursing : This research...Contract PoP: 6/1/2011 - 5/31/2016 Customer: TRISERVICE NURSING RESEARCH PROGRAM Customer Contract ID: HU0001 -11-1-TS02 Contract Manager: Robinson

  13. 48 CFR 622.406-1 - Policy.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 4 2011-10-01 2011-10-01 false Policy. 622.406-1 Section 622.406-1 Federal Acquisition Regulations System DEPARTMENT OF STATE SOCIOECONOMIC PROGRAMS....406-1 Policy. The cognizant contracting activity is the contracting agency for the purposes of FAR 22...

  14. 48 CFR 2822.101-3 - Reporting labor disputes.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Reporting labor disputes... Socioeconomic Programs APPLICATION OF LABOR LAWS TO GOVERNMENT ACQUISITIONS Basic Labor Policies 2822.101-3 Reporting labor disputes. The office administering the contract shall report, directly to the contracting...

  15. 48 CFR 53.219 - Small Business Programs.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false Small Business Programs... (CONTINUED) CLAUSES AND FORMS FORMS Prescription of Forms 53.219 Small Business Programs. (a) The following form may be used in reporting small disadvantaged business contracting data: OF 312 (10/00), Small...

  16. 48 CFR 53.219 - Small Business Programs.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 2 2012-10-01 2012-10-01 false Small Business Programs... (CONTINUED) CLAUSES AND FORMS FORMS Prescription of Forms 53.219 Small Business Programs. (a) The following form may be used in reporting small disadvantaged business contracting data: OF 312 (10/00), Small...

  17. 48 CFR 53.219 - Small Business Programs.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 2 2011-10-01 2011-10-01 false Small Business Programs... (CONTINUED) CLAUSES AND FORMS FORMS Prescription of Forms 53.219 Small Business Programs. (a) The following form may be used in reporting small disadvantaged business contracting data: OF 312 (10/00), Small...

  18. 48 CFR 53.219 - Small Business Programs.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 2 2014-10-01 2014-10-01 false Small Business Programs... (CONTINUED) CLAUSES AND FORMS FORMS Prescription of Forms 53.219 Small Business Programs. (a) The following form may be used in reporting small disadvantaged business contracting data: OF 312 (10/00), Small...

  19. 48 CFR 53.219 - Small Business Programs.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 2 2013-10-01 2013-10-01 false Small Business Programs... (CONTINUED) CLAUSES AND FORMS FORMS Prescription of Forms 53.219 Small Business Programs. (a) The following form may be used in reporting small disadvantaged business contracting data: OF 312 (10/00), Small...

  20. Trajectory and Force Control of a Direct Drive Arm.

    DTIC Science & Technology

    1986-09-01

    NUMBER 7. AUTNOn(s) . CONTRACT OR GRANT Ity൓"s ) Chae H. An N00014-80- C -- . O , 9. PERFORMING ORGANIZATION NAME AND ADDRESS 10. PROGRAM ELEMENT...and notations are used: 0 -W, WV CW { o ][:][ x] c (2.9) Wd X C -" W, 0 -W, cy -"X C (2) _-t V Wz 0 C , 11 󈧏 W, wy W, 0 0 0 112 112 W 0[ W. I0l (2.10) 0...theorem is used to compute the inertia terms translated to the center of mass of the load. C (2.16) )M Ji = P1- tn[(#TE)l -- (ZT)] (2.17) Then, the

  1. 10 CFR 800.002 - Program management.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 4 2013-01-01 2013-01-01 false Program management. 800.002 Section 800.002 Energy DEPARTMENT OF ENERGY LOANS FOR BID OR PROPOSAL PREPARATION BY MINORITY BUSINESS ENTERPRISES SEEKING DOE CONTRACTS AND ASSISTANCE General § 800.002 Program management. Program management responsibility for...

  2. 10 CFR 800.002 - Program management.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 4 2014-01-01 2014-01-01 false Program management. 800.002 Section 800.002 Energy DEPARTMENT OF ENERGY LOANS FOR BID OR PROPOSAL PREPARATION BY MINORITY BUSINESS ENTERPRISES SEEKING DOE CONTRACTS AND ASSISTANCE General § 800.002 Program management. Program management responsibility for...

  3. 10 CFR 800.002 - Program management.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 4 2011-01-01 2011-01-01 false Program management. 800.002 Section 800.002 Energy DEPARTMENT OF ENERGY LOANS FOR BID OR PROPOSAL PREPARATION BY MINORITY BUSINESS ENTERPRISES SEEKING DOE CONTRACTS AND ASSISTANCE General § 800.002 Program management. Program management responsibility for...

  4. 10 CFR 800.002 - Program management.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 4 2012-01-01 2012-01-01 false Program management. 800.002 Section 800.002 Energy DEPARTMENT OF ENERGY LOANS FOR BID OR PROPOSAL PREPARATION BY MINORITY BUSINESS ENTERPRISES SEEKING DOE CONTRACTS AND ASSISTANCE General § 800.002 Program management. Program management responsibility for...

  5. 10 CFR 800.002 - Program management.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Program management. 800.002 Section 800.002 Energy DEPARTMENT OF ENERGY LOANS FOR BID OR PROPOSAL PREPARATION BY MINORITY BUSINESS ENTERPRISES SEEKING DOE CONTRACTS AND ASSISTANCE General § 800.002 Program management. Program management responsibility for...

  6. Implementation of the Air Program Information Management System (APIMS) Inspection Module

    DTIC Science & Technology

    2009-05-01

    7 5 T H A I R B A S E W I N G Implementation of the Air Program Information Management System (APIMS) Inspection Module 2009 Environment...Implementation of the Air Program Information Management System (APIMS) Inspection Module 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER

  7. 48 CFR 1835.016-71 - NASA Research Announcements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true NASA Research Announcements... ADMINISTRATION SPECIAL CATEGORIES OF CONTRACTING RESEARCH AND DEVELOPMENT CONTRACTING 1835.016-71 NASA Research Announcements. (a) Scope. An NRA is used to announce research interests in support of NASA's programs, and...

  8. 42 CFR 52h.12 - Other regulations that apply.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Other regulations that apply. 52h.12 Section 52h.12 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS SCIENTIFIC PEER REVIEW OF RESEARCH GRANT APPLICATIONS AND RESEARCH AND DEVELOPMENT CONTRACT PROJECTS § 52h.12 Other...

  9. 48 CFR 352.270-3 - Indian preference program.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 4 2011-10-01 2011-10-01 false Indian preference program... Indian preference program. As prescribed in 370.202(b), the Contracting Officer shall insert the following clause: Indian Preference Program (January 2006) (a) In addition to the requirements of the clause...

  10. 48 CFR 352.270-3 - Indian preference program.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 4 2013-10-01 2013-10-01 false Indian preference program... Indian preference program. As prescribed in 370.202(b), the Contracting Officer shall insert the following clause: Indian Preference Program (January 2006) (a) In addition to the requirements of the clause...

  11. 48 CFR 352.270-3 - Indian preference program.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Indian preference program... Indian preference program. As prescribed in 370.202(b), the Contracting Officer shall insert the following clause: Indian Preference Program (January 2006) (a) In addition to the requirements of the clause...

  12. 48 CFR 352.270-3 - Indian preference program.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 4 2014-10-01 2014-10-01 false Indian preference program... Indian preference program. As prescribed in 370.202(b), the Contracting Officer shall insert the following clause: Indian Preference Program (January 2006) (a) In addition to the requirements of the clause...

  13. 48 CFR 352.270-3 - Indian preference program.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 4 2012-10-01 2012-10-01 false Indian preference program... Indian preference program. As prescribed in 370.202(b), the Contracting Officer shall insert the following clause: Indian Preference Program (January 2006) (a) In addition to the requirements of the clause...

  14. 48 CFR 1419.803 - Selecting acquisitions for the 8(a) Program.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Selecting acquisitions for the 8(a) Program. 1419.803 Section 1419.803 Federal Acquisition Regulations System DEPARTMENT OF THE INTERIOR SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Contracting with the Small Business Administration...

  15. 48 CFR 19.801 - [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false [Reserved] 19.801 Section 19.801 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Contracting With the Small Business Administration (the 8(a) Program) 19.801...

  16. 75 FR 71064 - Medicare Program; Proposed Changes to the Medicare Advantage and the Medicare Prescription Drug...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-22

    ... and the Medicare Prescription Drug Benefit Programs for Contract Year 2012 and Other Proposed Changes... for Contract Year 2012 and Other Proposed Changes'' which was filed for public inspection on November 10, 2010. FOR FURTHER INFORMATION CONTACT: Sabrina Ahmed, (410) 786-7499. SUPPLEMENTARY INFORMATION...

  17. Antimicrobial Resistance and Molecular Typing of Neisseria gonorrhoeae Isolates in Kyoto and Osaka, Japan, 2010 to 2012: Intensified Surveillance after Identification of the First Strain (H041) with High-Level Ceftriaxone Resistance

    PubMed Central

    Shimuta, Ken; Unemo, Magnus; Nakayama, Shu-ichi; Morita-Ishihara, Tomoko; Dorin, Misato; Kawahata, Takuya

    2013-01-01

    In 2009, the first high-level ceftriaxone-resistant Neisseria gonorrhoeae strain (H041) was isolated in Kyoto, Japan. The present study describes an intensified surveillance (antimicrobial resistance and molecular typing) of Neisseria gonorrhoeae isolates in Kyoto and its neighboring prefecture Osaka, Japan, in 2010 to 2012, which was initiated after the identification of H041. From April 2010 to March 2012, 193 N. gonorrhoeae isolates were collected and the MICs (μg/ml) to six antimicrobials, including ceftriaxone, were determined. All isolates showed susceptibility to ceftriaxone and cefixime (MIC values, <0.5 μg/ml), and spectinomycin. The rates of resistance (intermediate susceptibility) to azithromycin, penicillin G, and ciprofloxacin were 3.6% (19.7%), 24.4% (71.0%), and 78.2% (0.5%), respectively. Multilocus sequence typing (MLST) showed that 40.9%, 19.2%, and 17.1% of isolates belonged to ST1901, ST7359, and ST7363, respectively. Furthermore, N. gonorrhoeae multiantigen sequence typing (NG-MAST) revealed that 12 (63%) of the 19 isolates with decreased susceptibility to ceftriaxone (MIC > 0.064 μg/ml) were of ST1407. NG-MAST ST1407 was also the most prevalent ST (16.1%; 31 of 193 isolates). In those NG-MAST ST1407 strains, several mosaic type penA alleles were found, including SF-A type (penicillin binding protein 2 allele XXXIV) and its derivatives. These were confirmed using transformation of the penA mosaic alleles as critical determinants for enhanced cefixime and ceftriaxone MICs. The intensified surveillance in Kyoto and Osaka, Japan, did not identify any dissemination of the high-level ceftriaxone-resistant N. gonorrhoeae strain H041, suggesting that H041 might have caused only a sporadic case and has not spread further. PMID:23939890

  18. Stretch-sensitive paresis and effort perception in hemiparesis.

    PubMed

    Vinti, Maria; Bayle, Nicolas; Hutin, Emilie; Burke, David; Gracies, Jean-Michel

    2015-08-01

    In spastic paresis, stretch applied to the antagonist increases its inappropriate recruitment during agonist command (spastic co-contraction). It is unknown whether antagonist stretch: (1) also affects agonist recruitment; (2) alters effort perception. We quantified voluntary activation of ankle dorsiflexors, effort perception, and plantar flexor co-contraction during graded dorsiflexion efforts at two gastrocnemius lengths. Eighteen healthy (age 41 ± 13) and 18 hemiparetic (age 54 ± 12) subjects performed light, medium and maximal isometric dorsiflexion efforts with the knee flexed or extended. We determined dorsiflexor torque, Root Mean Square EMG and Agonist Recruitment/Co-contraction Indices (ARI/CCI) from the 500 ms peak voluntary agonist recruitment in a 5-s maximal isometric effort in tibialis anterior, soleus and medial gastrocnemius. Subjects retrospectively reported effort perception on a 10-point visual analog scale. During gastrocnemius stretch in hemiparetic subjects, we observed: (1) a 25 ± 7 % reduction of tibialis anterior voluntary activation (maximum reduction 98 %; knee extended vs knee flexed; p = 0.007, ANOVA); (2) an increase in dorsiflexion effort perception (p = 0.03, ANCOVA). Such changes did not occur in healthy subjects. Effort perception depended on tibialis anterior recruitment only (βARI(TA) = 0.61, p < 0.01) in healthy subjects (not on gastrocnemius medialis co-contraction) while it depended on both tibialis anterior agonist recruitment (βARI(TA) = 0.41, p < 0.001) and gastrocnemius medialis co-contraction (βCCI(MG) = 0.43, p < 0.001) in hemiparetic subjects. In hemiparesis, voluntary ability to recruit agonist motoneurones is impaired--sometimes abolished--by antagonist stretch, a phenomenon defined here as stretch-sensitive paresis. In addition, spastic co-contraction increases effort perception, an additional incentive to evaluate and treat this phenomenon.

  19. Confidence Region for the Evaluation of HF DF Single Site Location Systems.

    DTIC Science & Technology

    1983-09-02

    CONTRACT ORt GRANT NUMBER(@) M.H. Reilly and J. Coran S. PERFORMING ORGANIZATION NAME AND ADDRESS WD PROGRAM ELEMENT. PROJECTAS Naval Research...1 DETERMINATION OF THE CONFIDENCE REGION....................2 COMPUTER PROGRAM FOR THE CONFIDENCE ELLIPSE..............5 EXAMPLES OF COMPUTER... PROGRAM OUTPUT......................6 DISCUSSION ................................................... 7 ACKNOWLEDGMENTS

  20. 48 CFR 2132.607 - Tax credit.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 6 2011-10-01 2011-10-01 false Tax credit. 2132.607... Contract Debts 2132.607 Tax credit. FAR 32.607 has no practical application to FEGLI Program contracts. The... Government, contractors may not offset debts to the Fund by a tax credit that is solely a Government...

  1. 42 CFR 136.350 - Contracts with Urban Indian organizations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Contracts with Urban Indian organizations. 136.350 Section 136.350 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES INDIAN HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES INDIAN HEALTH Indian Health Care Improvement Act Programs...

  2. 48 CFR 423.506 - Suspension of payments, termination of contract, and debarment and suspension actions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 4 2014-10-01 2014-10-01 false Suspension of payments, termination of contract, and debarment and suspension actions. 423.506 Section 423.506 Federal Acquisition Regulations System DEPARTMENT OF AGRICULTURE SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY...

  3. 48 CFR 423.506 - Suspension of payments, termination of contract, and debarment and suspension actions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Suspension of payments, termination of contract, and debarment and suspension actions. 423.506 Section 423.506 Federal Acquisition Regulations System DEPARTMENT OF AGRICULTURE SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY...

  4. 48 CFR 423.506 - Suspension of payments, termination of contract, and debarment and suspension actions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 4 2011-10-01 2011-10-01 false Suspension of payments, termination of contract, and debarment and suspension actions. 423.506 Section 423.506 Federal Acquisition Regulations System DEPARTMENT OF AGRICULTURE SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY...

  5. 48 CFR 423.506 - Suspension of payments, termination of contract, and debarment and suspension actions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 4 2013-10-01 2013-10-01 false Suspension of payments, termination of contract, and debarment and suspension actions. 423.506 Section 423.506 Federal Acquisition Regulations System DEPARTMENT OF AGRICULTURE SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY...

  6. 48 CFR 423.506 - Suspension of payments, termination of contract, and debarment and suspension actions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 4 2012-10-01 2012-10-01 false Suspension of payments, termination of contract, and debarment and suspension actions. 423.506 Section 423.506 Federal Acquisition Regulations System DEPARTMENT OF AGRICULTURE SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY...

  7. 42 CFR 136.350 - Contracts with Urban Indian organizations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false Contracts with Urban Indian organizations. 136.350 Section 136.350 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES INDIAN HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES INDIAN HEALTH Indian Health Care Improvement Act Programs...

  8. 42 CFR 136.350 - Contracts with Urban Indian organizations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 1 2014-10-01 2014-10-01 false Contracts with Urban Indian organizations. 136.350 Section 136.350 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES INDIAN HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES INDIAN HEALTH Indian Health Care Improvement Act Programs...

  9. 42 CFR 136.350 - Contracts with Urban Indian organizations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 1 2012-10-01 2012-10-01 false Contracts with Urban Indian organizations. 136.350 Section 136.350 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES INDIAN HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES INDIAN HEALTH Indian Health Care Improvement Act Programs...

  10. 42 CFR 136.350 - Contracts with Urban Indian organizations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 1 2013-10-01 2013-10-01 false Contracts with Urban Indian organizations. 136.350 Section 136.350 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES INDIAN HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES INDIAN HEALTH Indian Health Care Improvement Act Programs...

  11. 48 CFR 319.270-1 - Solicitation provision and contract clause.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 4 2011-10-01 2011-10-01 false Solicitation provision and contract clause. 319.270-1 Section 319.270-1 Federal Acquisition Regulations System HEALTH AND HUMAN... Program, in solicitations that include the clause in FAR 52.219-9, Small Business Subcontracting Plan. The...

  12. 48 CFR 319.270-1 - Solicitation provision and contract clause.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 4 2013-10-01 2013-10-01 false Solicitation provision and contract clause. 319.270-1 Section 319.270-1 Federal Acquisition Regulations System HEALTH AND HUMAN... Program, in solicitations that include the clause in FAR 52.219-9, Small Business Subcontracting Plan. The...

  13. 48 CFR 2132.607 - Tax credit.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Tax credit. 2132.607... Contract Debts 2132.607 Tax credit. FAR 32.607 has no practical application to FEGLI Program contracts. The... Government, contractors may not offset debts to the Fund by a tax credit that is solely a Government...

  14. Semiannual Technical Summary, 1 October 1990 - 31 March 1991 (Royal Norwegian Council for Scientific and Industrial Research)

    DTIC Science & Technology

    1991-05-01

    Ronal Njorwegian Council !,r ScrerithC arid Industrial RuseIarch R A YI~L ~ AD-A242 758 NORSAR Scientific Report No . 2-90/91 Semiannual Technical...Authorization T/9141/B/PKP ARPA Order No . 4138 AMD # 16 Program Code No . OF10 Name of Contractor Royal Norwegian Council for Scientific and Industrial ...PROCUREMENT INSTRUMENT IDENTIFICATION NUMBER ORGANIZATION Defense Advanced -- "’able) Contract No . F08606-89-C-0005 Pae~h rjsct A ..... 8c. ADDRESS (Ci-tytate

  15. 42 CFR 52h.10 - What matters must be reviewed for solicited contract proposals?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... with respect to a contract project involving solicited contract proposals, unless the project concept... group has made recommendations concerning the scientific merit of the concept. (b) The awarding official... review of the project concept and the proposals has been completed. The request for proposals shall state...

  16. A comparative study of job satisfaction among regular and staff on contract in the primary health care system in Delhi, India

    PubMed Central

    Kumar, Pawan; Khan, Abdul M.; Inder, Deep; Mehra, Anu

    2014-01-01

    Background: Job satisfaction is a pleasant emotional state associated with the appreciation of one's work and contributes immensely to performance in an organization. The purpose of this study was to assess the comparative job satisfaction among regular and staff on contract in Government Primary Urban Health Centers in Delhi, India. Materials and Methods: The study was conducted in 2013, on a sample of 333 health care providers who were selected using a multistage random sampling technique. The sample included medical officers (MOs), auxiliary nurses and midwives (ANMs), pharmacists and laboratory technicians (LTs)/laboratory assistants (LAs) among regular and staff on contract. Analysis was done using SPSS version 18, and appropriate statistical tests were applied. Results: The job satisfaction for all the regular staff that is, MOs, ANMs, pharmacists, LAs, and LTs were relatively higher (3.3 ± 0.44) than the contract staff (2.7 ± 0.45) with ‘t’value 10.54 (P < 0.01). The mean score for regular and contract MOs was 3.2 ± 0.46 and 2.7 ± 0.56, respectively, and the same trends were found between regular and ANMs on the contract which was 3.4 ± 0.30 and 2.7 ± 0.38, regular and pharmacists on the contract was 3.3 ± 0.50 and 2.8 ± 0.41, respectively. The differences between groups were significant with a P < 0.01. Conclusion: Overall job satisfaction level was relatively low in both regular and contract staff. The factors contributing to satisfaction level were privileges, interpersonal relations, working-environment, patient relationship, the organization's facilities, career development, and the scarcity of human resources (HRs). Therefore, specific recommendations are suggested to policy makers to take cognizance of the scarcity of HRs and the on-going experimentation with different models under primary health care system. PMID:24987280

  17. Protons act as a transmitter for muscle contraction in C. elegans.

    PubMed

    Beg, Asim A; Ernstrom, Glen G; Nix, Paola; Davis, M Wayne; Jorgensen, Erik M

    2008-01-11

    Muscle contraction is normally mediated by the release of neurotransmitters from motor neurons. Here we demonstrate that protons can act as a direct transmitter from intestinal cells to stimulate muscle contraction. During the C. elegans defecation motor program the posterior body muscles contract even in the absence of neuronal inputs or vesicular neurotransmission. In this study, we demonstrate that the space between the intestine and the muscle is acidified just prior to muscle contraction and that the release of caged protons is sufficient to induce muscle contraction. PBO-4 is a putative Na+/H+ ion exchanger expressed on the basolateral membrane of the intestine, juxtaposed to the posterior body muscles. In pbo-4 mutants the extracellular space is not acidified and the muscles fail to contract. The pbo-5 and pbo-6 genes encode subunits of a "cys-loop" proton-gated cation channel required for muscles to respond to acidification. In heterologous expression assays the PBO receptor is half-maximally activated at a pH of 6.8. The identification of the mechanisms for release and reception of proton signals establishes a highly unusual mechanism for intercellular communication.

  18. Contracts and management services site support program plan WBS 6.10.14

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Knoll, J.M. Jr.

    1994-09-01

    Contracts and Management Services is recognized as the central focal point for programs having company or sitewide application in pursuit of the Hanford Missions`s financial and operational objectives. Contracts and Management Services actively pursues cost savings and operational efficiencies through: Management Standards by ensuring all employees have an accessible, integrated system of clear, complete, accurate, timely, and useful management control policies and procedures; Contract Reform by restructuring the contract, organization, and cost accounting systems to refocus Hanford contract activities on output products; Systems and Operations Evaluation by directing the Cost Reduction program, Great Ideas, and Span of Management activities; Programmore » Administration by enforcing conditions of Accountability (whether DEAR-based or FAR-based) for WHC, BCSR, ICF KH, and BHI; Contract Performance activities; chairing the WHC Cost Reduction Review Board; and analyzing companywide Performance Measures; Data Standards and Administration by establishing and directing the company data management program; giving direction to the major RL programs and mission areas for implementation of cost-effective and efficient data management practices; directing all operations, application, and interfaces contained within the Hanford PeopleCore System; directing accomplishment and delivery of TPA data management milestones; and directing the sitewide data management processes for Data Standards and the Data Directory.« less

  19. 42 CFR 421.205 - Termination by the Secretary.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 3 2014-10-01 2014-10-01 false Termination by the Secretary. 421.205 Section 421... (CONTINUED) MEDICARE PROGRAM (CONTINUED) MEDICARE CONTRACTING Carriers § 421.205 Termination by the Secretary. (a) Cause for termination. The Secretary may terminate a contract with a carrier at any time if he or...

  20. 42 CFR 457.955 - Conditions necessary to contract as a managed care entity (MCE).

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... separate child health program has administrative and management arrangements or procedures designed to... 42 Public Health 4 2012-10-01 2012-10-01 false Conditions necessary to contract as a managed care entity (MCE). 457.955 Section 457.955 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT...

  1. 42 CFR 457.955 - Conditions necessary to contract as a managed care entity (MCE).

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... separate child health program has administrative and management arrangements or procedures designed to... 42 Public Health 4 2014-10-01 2014-10-01 false Conditions necessary to contract as a managed care entity (MCE). 457.955 Section 457.955 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT...

  2. Department of Defense Prime Contract Awards Over $25,000 by Weapon System, Contractor and Work Performed. Fiscal Year 1993. (AAA Navy A-1 Skyraider-SMR Navy Harbor IGE YTB)

    DTIC Science & Technology

    1994-03-01

    ui ac < 10 Z BPP - ft ~ F.UB O 00)-m BGBBN Cr (0jW-4 () 0 NO 000-4 C4 r)NB 4 V V ~C% O : 0 B . C)O:M-4 WO GONO=O -4 NC’)c)(0-V B N M0.-4 MMMOCr-MM~ M...0 L. CW 0 ) - L-a L.C a4*.4 CUOI Q, O. C I.-4 Co. E 4on _1 ’ 4 L. 1.C C- E.4 -041-- E.4 U U. 0 C I I 0 4 W; C C. X - ..41- 5. in C &I.U 5L. L Sbl W4

  3. 41 CFR 51-10.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Other Provisions Relating to Public Contracts COMMITTEE FOR PURCHASE FROM PEOPLE WHO ARE BLIND OR... CONDUCTED BY THE COMMITTEE FOR PURCHASE FROM PEOPLE WHO ARE BLIND OR SEVERELY DISABLED § 51-10.151 Program...

  4. 41 CFR 51-10.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Other Provisions Relating to Public Contracts COMMITTEE FOR PURCHASE FROM PEOPLE WHO ARE BLIND OR... CONDUCTED BY THE COMMITTEE FOR PURCHASE FROM PEOPLE WHO ARE BLIND OR SEVERELY DISABLED § 51-10.151 Program...

  5. 41 CFR 51-10.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Other Provisions Relating to Public Contracts COMMITTEE FOR PURCHASE FROM PEOPLE WHO ARE BLIND OR... CONDUCTED BY THE COMMITTEE FOR PURCHASE FROM PEOPLE WHO ARE BLIND OR SEVERELY DISABLED § 51-10.151 Program...

  6. Why is cytoskeletal contraction required for cardiac fusion before but not after looping begins?

    NASA Astrophysics Data System (ADS)

    Shi, Yunfei; Varner, Victor D.; Taber, Larry A.

    2015-02-01

    Cytoskeletal contraction is crucial to numerous morphogenetic processes, but its role in early heart development is poorly understood. Studies in chick embryos have shown that inhibiting myosin-II-based contraction prior to Hamburger-Hamilton (HH) stage 10 (33 h incubation) impedes fusion of the mesodermal heart fields that create the primitive heart tube (HT), as well as the ensuing process of cardiac looping. If contraction is inhibited at or after looping begins at HH10, however, fusion and looping proceed relatively normally. To explore the mechanisms behind this seemingly fundamental change in behavior, we measured spatiotemporal distributions of tissue stiffness, stress, and strain around the anterior intestinal portal (AIP), the opening to the foregut where contraction and cardiac fusion occur. The results indicate that stiffness and tangential tension decreased bilaterally along the AIP with distance from the embryonic midline. The gradients in stiffness and tension, as well as strain rate, increased to peaks at HH9 (30 h) and decreased afterward. Exposure to the myosin II inhibitor blebbistatin reduced these effects, suggesting that they are mainly generated by active cytoskeletal contraction, and finite-element modeling indicates that the measured mechanical gradients are consistent with a relatively uniform contraction of the endodermal layer in conjunction with constraints imposed by the attached mesoderm. Taken together, our results suggest that, before HH10, endodermal contraction pulls the bilateral heart fields toward the midline where they fuse to create the HT. By HH10, however, the fusion process is far enough along to enable apposing cardiac progenitor cells to keep ‘zipping’ together during looping without the need for continued high contractile forces. These findings should shed new light on a perplexing question in early heart development.

  7. 48 CFR 952.219-70 - DOE Mentor-Protege program.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false DOE Mentor-Protege program... FORMS SOLICITATION PROVISIONS AND CONTRACT CLAUSES Text of Provisions and Clauses 952.219-70 DOE Mentor.... DOE Mentor-Protege Program (MAY 2000) The Department of Energy has established a Mentor-Protege...

  8. 48 CFR 1452.226-71 - Indian Preference Program.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 5 2013-10-01 2013-10-01 false Indian Preference Program... Indian Preference Program. As prescribed in 1426.7003(b), insert the following clause in all... work under the contract will be performed in whole or in part on or near an Indian reservation(s). The...

  9. 48 CFR 1452.226-71 - Indian Preference Program.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Indian Preference Program... Indian Preference Program. As prescribed in 1426.7003(b), insert the following clause in all... work under the contract will be performed in whole or in part on or near an Indian reservation(s). The...

  10. 48 CFR 1452.226-71 - Indian Preference Program.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 5 2014-10-01 2014-10-01 false Indian Preference Program... Indian Preference Program. As prescribed in 1426.7003(b), insert the following clause in all... work under the contract will be performed in whole or in part on or near an Indian reservation(s). The...

  11. 48 CFR 1452.226-71 - Indian Preference Program.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 5 2012-10-01 2012-10-01 false Indian Preference Program... Indian Preference Program. As prescribed in 1426.7003(b), insert the following clause in all... work under the contract will be performed in whole or in part on or near an Indian reservation(s). The...

  12. 48 CFR 1452.226-71 - Indian Preference Program.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Indian Preference Program... Indian Preference Program. As prescribed in 1426.7003(b), insert the following clause in all... work under the contract will be performed in whole or in part on or near an Indian reservation(s). The...

  13. Phosphorylation of h1 Calponin by PKC epsilon may contribute to facilitate the contraction of uterine myometrium in mice during pregnancy and labor

    PubMed Central

    2012-01-01

    Background The timely onset of powerful uterine contractions during parturition occurs through thick and thin filament interactions, similar to other smooth muscle tissues. Calponin is one of the thin filament proteins. Phosphorylation of calponin induced by PKC-epsilon can promote the contraction of vascular smooth muscle. While the mechanism by which calponin regulates the contraction of pregnant myometrium has rarely been explored. Here, we explore whether PKC-epsilon/h1 calponin pathway contribute to regulation of myometrial contractility and development of parturition. Methods We detected the expression of h1 calponin, phosphorylated h1 calponin, PKC-epsilon and phosphorylated PKC-epsilon in the different stages of mice during pregnancy and in labor by the method of western blot and recorded the contraction activity of myometrium strips at the 19th day during pregnancy with different treatments by the organ bath experiments. Results The level of the four proteins including h1 calponin, phosphorylated h1 calponin, PKC-epsilon and phosphorylated PKC-epsilon was significantly increased in pregnant mice myometrium as compared with that in nonpregnant mice. The ratios of phosphorylated h1 calponin/h1 calponin and phosphorylated PKC-epsilon/PKC-epsilon were reached the peak after the onset of labor in myometrium in the mice. After the treatment of more than 10(9-) mol/L Psi-RACK (PKC-epsilon activator), the contractility of myometrium strips from mice was reinforced and the level of phosphorylated h1 calponin increased at the same time which could be interrupted by the specific inhibitor of PKC-epsilon. Meanwhile, the change of the ratio of phosphorylated h1 calponin/h1 calponin was consistent with that of contraction force of mice myometrium strips. Conclusions These data suggest that in mice myometrium, phosphorylation of h1 calponin induced by the PKC-epsilon might facilitate the contraction of uterine in labor and regulate pregnant myometrial contractility. PMID:22551221

  14. 48 CFR 19.809 - Preaward considerations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Preaward considerations. 19.809 Section 19.809 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Contracting With the Small Business Administration (the 8(a...

  15. 75 FR 17403 - Great Bay Hydro Corporation; Notice of Application for Amendment of License and Soliciting...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-06

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 2306-041] Great Bay Hydro.... b. Project No.: 2306-041. c. Date Filed: March 1, 2010. d. Applicant: Great Bay Hydro Corporation. e...-825r. h. Applicant Contact: Mr. William C. Rodgers, Director of Marketing, Great Bay Hydro Corporation...

  16. Defense Contracting: Actions Needed to Explore Additional Opportunities to Gain Efficiencies in Acquiring Foreign Language Support

    DTIC Science & Technology

    2013-02-25

    Directive 5160.41E, Defense Language Program . 10GAO-11-456. Page 5 GAO-13-251R Defense Contracting types of foreign language support that DOD has acquired...Language Transformation Roadmap, (January 2005), and Department of Defense Directive 5160.41E, Defense Language Program . Page 15 GAO-13-251R Defense...examines the use of public funds; evaluates federal programs and policies; and provides analyses, recommendations, and other assistance to help

  17. Assessment of medical occupational radiation doses in Costa Rica.

    PubMed

    Mora, P; Acuña, M

    2011-09-01

    Participation of the University of Costa Rica (UCR) in activities in an IAEA Regional Project RLA/9/066 through training, equipment and expert missions, has enabled to setting up of a national personal monitoring laboratory. Since 2007, the UCR has been in charge of monitoring around 1800 medical radiation workers of the Social Security System. Individual external doses are measured with thermoluminescent dosemeter using a Harshaw 6600 Plus reader. The service has accreditation with ISO/IEC 17025:2005. Distribution of monitored medical personnel is as follows: 83 % in diagnostic radiology, 6 % in nuclear medicine and 6 % in radiotherapy. Preliminary values for the 75 percentile of annual H(p)(10) in mSv are: radiology 0.37; interventional radiology 0.41; radiotherapy 0.53 and nuclear medicine 1.55. The service provided by the UCR in a steady and reliable way can help to implement actions to limit the doses received by the medical workers and optimise their radiation protection programs.

  18. 48 CFR 1426.7103-2 - Requirements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 5 2014-10-01 2014-10-01 false Requirements. 1426.7103-2 Section 1426.7103-2 Federal Acquisition Regulations System DEPARTMENT OF THE INTERIOR SOCIOECONOMIC PROGRAMS OTHER SOCIOECONOMIC PROGRAMS Minority Business Reports 1426.7103-2 Requirements. The contracting...

  19. 49 CFR 26.39 - Fostering small business participation.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 1 2012-10-01 2012-10-01 false Fostering small business participation. 26.39... BUSINESS ENTERPRISES IN DEPARTMENT OF TRANSPORTATION FINANCIAL ASSISTANCE PROGRAMS Administrative Requirements for DBE Programs for Federally-Assisted Contracting § 26.39 Fostering small business participation...

  20. 49 CFR 26.39 - Fostering small business participation.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 1 2011-10-01 2011-10-01 false Fostering small business participation. 26.39... BUSINESS ENTERPRISES IN DEPARTMENT OF TRANSPORTATION FINANCIAL ASSISTANCE PROGRAMS Administrative Requirements for DBE Programs for Federally-Assisted Contracting § 26.39 Fostering small business participation...

  1. 48 CFR 970.3002 - CAS program requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false CAS program requirements. 970.3002 Section 970.3002 Federal Acquisition Regulations System DEPARTMENT OF ENERGY AGENCY SUPPLEMENTARY REGULATIONS DOE MANAGEMENT AND OPERATING CONTRACTS Cost Accounting Standards Administration 970...

  2. 7 CFR 1463.109 - Contracts.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Contracts. 1463.109 Section 1463.109 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS 2005-2014 TOBACCO TRANSITION PROGRAM Tobacco Transition...

  3. Medical Surveillance Monthly Report (MSMR). Volume 16, Number 4, April 2009

    DTIC Science & Technology

    2009-04-01

    April 2009 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR (S) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER...Hepatitis A (μ: 10) Hantavirus disease (μ: 3) Brucellosis (μ: 2) E. coli O157:H7 (μ: 3) West Nile virus (μ: 6) Dengue fever (μ: 4) Ehrlichiosis (μ...uenzae, invasive 0 0 2 2 14 Hantavirus disease 0 6 2 0 0 Heat exhaustion 542 727 566 547 452 Heat stroke 196 163 128 133 145 Hemorrhagic fever 0 0 0

  4. Blood harmane is correlated with cerebellar metabolism in essential tremor: a pilot study.

    PubMed

    Louis, Elan D; Zheng, Wei; Mao, Xiangling; Shungu, Dikoma C

    2007-08-07

    On proton magnetic resonance spectroscopic imaging ((1)H MRSI), there is a decrease in cerebellar N-acetylaspartate/total creatine (NAA/tCr) in essential tremor (ET), signifying cerebellar neuronal dysfunction or degeneration. Harmane, which is present in the human diet, is a potent tremor-producing neurotoxin. Blood harmane concentrations seem to be elevated in ET. To assess in patients with ET whether blood harmane concentration is correlated with cerebellar NAA/tCR, a neuroimaging measure of neuronal dysfunction or degeneration. Twelve patients with ET underwent (1)H MRSI. The major neuroanatomic structure of interest was the cerebellar cortex. Secondary regions were the central cerebellar white matter, cerebellar vermis, thalamus, and basal ganglia. Blood concentrations of harmane and another neurotoxin, lead, were also assessed. Mean +/- SD cerebellar NAA/tCR was 1.52 +/- 0.41. In a linear regression model that adjusted for age and gender, log blood harmane concentration was a predictor of cerebellar NAA/tCR (beta = -0.41, p = 0.009); every 1 g(-10)/mL unit increase in log blood harmane concentration was associated with a 0.41 unit decrease in cerebellar NAA/tCR. The association between blood harmane concentration and brain NAA/tCR only occurred in the cerebellar cortex; it was not observed in secondary brain regions of interest. Furthermore, the association was specific to harmane and not another neurotoxin, lead. This study provides additional support for the emerging link between harmane, a neurotoxin, and ET. Further studies are warranted to address whether cerebellar harmane concentrations are associated with cerebellar pathology in postmortem studies of the ET brain.

  5. Protons act as a transmitter for muscle contraction in C. elegans

    PubMed Central

    Beg, Asim A.; Ernstrom, Glen G.; Nix, Paola; Davis, M. Wayne; Jorgensen, Erik M.

    2008-01-01

    Muscle contraction is normally mediated by the release of neurotransmitters from motor neurons. Here we demonstrate that protons can act as a direct transmitter from intestinal cells to stimulate muscle contraction. During the C. elegans defecation motor program the posterior body muscles contract even in the absence of neuronal inputs or vesicular neurotransmission. In this study, we demonstrate that the space between the intestine and the muscle is acidified just prior to muscle contraction and that the release of caged protons is sufficient to induce muscle contraction. PBO-4 is a putative Na+/H+ ion exchanger expressed on the basolateral membrane of the intestine, juxtaposed to the posterior body muscles. In pbo-4 mutants the extracellular space is not acidified and the muscles fail to contract. The pbo-5 and pbo-6 genes encode subunits of a ‘cys-loop’ proton-gated cation channel required for muscles to respond to acidification. In heterologous expression assays the PBO receptor is half-maximally activated at a pH of 6.8. The identification of the mechanisms for release and reception of proton signals establishes a highly unusual mechanism for intercellular communication. PMID:18191228

  6. 77 FR 43723 - Energy Efficiency and Conservation Loan Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-26

    ... communities by investing in energy efficiency, and (5) encouraging the use of renewable energy fuels for both... contracts. Impacts The new Subpart H. for the Energy Efficiency and Conservation Loan Program can have several economic impacts. The benefits include: (1) The value of purchased energy saved; (2) the value of...

  7. 48 CFR 1815.407-2 - Make-or-buy programs. (NASA supplements paragraph (e))

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 6 2013-10-01 2013-10-01 false Make-or-buy programs. (NASA supplements paragraph (e)) 1815.407-2 Section 1815.407-2 Federal Acquisition Regulations System... NEGOTIATION Contract Pricing 1815.407-2 Make-or-buy programs. (NASA supplements paragraph (e)) (e)(1) Make-or...

  8. 48 CFR 1815.407-2 - Make-or-buy programs. (NASA supplements paragraph (e))

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 6 2011-10-01 2011-10-01 false Make-or-buy programs. (NASA supplements paragraph (e)) 1815.407-2 Section 1815.407-2 Federal Acquisition Regulations System... NEGOTIATION Contract Pricing 1815.407-2 Make-or-buy programs. (NASA supplements paragraph (e)) (e)(1) Make-or...

  9. 48 CFR 252.225-7000 - Buy American Act-Balance of Payments Program Certificate.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Buy American Act-Balance... PROVISIONS AND CONTRACT CLAUSES Text of Provisions And Clauses 252.225-7000 Buy American Act—Balance of Payments Program Certificate. Buy American Act—Balance of Payments Program Certificate (DEC 2009) (a...

  10. 48 CFR 1644.170 - Policy for FEHB Program subcontracting.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 6 2014-10-01 2014-10-01 false Policy for FEHB Program subcontracting. 1644.170 Section 1644.170 Federal Acquisition Regulations System OFFICE OF PERSONNEL MANAGEMENT FEDERAL EMPLOYEES HEALTH BENEFITS ACQUISITION REGULATION CONTRACT MANAGEMENT SUBCONTRACTING POLICIES AND...

  11. 48 CFR 1644.170 - Policy for FEHB Program subcontracting.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 6 2013-10-01 2013-10-01 false Policy for FEHB Program subcontracting. 1644.170 Section 1644.170 Federal Acquisition Regulations System OFFICE OF PERSONNEL MANAGEMENT FEDERAL EMPLOYEES HEALTH BENEFITS ACQUISITION REGULATION CONTRACT MANAGEMENT SUBCONTRACTING POLICIES AND...

  12. 48 CFR 1644.170 - Policy for FEHB Program subcontracting.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 6 2011-10-01 2011-10-01 false Policy for FEHB Program subcontracting. 1644.170 Section 1644.170 Federal Acquisition Regulations System OFFICE OF PERSONNEL MANAGEMENT FEDERAL EMPLOYEES HEALTH BENEFITS ACQUISITION REGULATION CONTRACT MANAGEMENT SUBCONTRACTING POLICIES AND...

  13. 48 CFR 1644.170 - Policy for FEHB Program subcontracting.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 6 2012-10-01 2012-10-01 false Policy for FEHB Program subcontracting. 1644.170 Section 1644.170 Federal Acquisition Regulations System OFFICE OF PERSONNEL MANAGEMENT FEDERAL EMPLOYEES HEALTH BENEFITS ACQUISITION REGULATION CONTRACT MANAGEMENT SUBCONTRACTING POLICIES AND...

  14. 48 CFR 919.7013 - Reports.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 5 2012-10-01 2012-10-01 false Reports. 919.7013 Section... BUSINESS PROGRAMS The Department of Energy Mentor-Protege Program 919.7013 Reports. (a) Prior to performing... submit semi-annual reports to the cognizant contracting officer regarding the participating Mentor's...

  15. 48 CFR 919.7013 - Reports.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Reports. 919.7013 Section... BUSINESS PROGRAMS The Department of Energy Mentor-Protege Program 919.7013 Reports. (a) Prior to performing... submit semi-annual reports to the cognizant contracting officer regarding the participating Mentor's...

  16. 48 CFR 919.7013 - Reports.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 5 2013-10-01 2013-10-01 false Reports. 919.7013 Section... BUSINESS PROGRAMS The Department of Energy Mentor-Protege Program 919.7013 Reports. (a) Prior to performing... submit semi-annual reports to the cognizant contracting officer regarding the participating Mentor's...

  17. 48 CFR 19.505 - Rejecting Small Business Administration recommendations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 1 2013-10-01 2013-10-01 false Rejecting Small Business... REGULATION SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Set-Asides for Small Business 19.505 Rejecting Small Business Administration recommendations. (a) If the contracting officer rejects a recommendation...

  18. 48 CFR 19.505 - Rejecting Small Business Administration recommendations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 1 2014-10-01 2014-10-01 false Rejecting Small Business... REGULATION SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Set-Asides for Small Business 19.505 Rejecting Small Business Administration recommendations. (a) If the contracting officer rejects a recommendation...

  19. 48 CFR 19.505 - Rejecting Small Business Administration recommendations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 1 2012-10-01 2012-10-01 false Rejecting Small Business... REGULATION SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Set-Asides for Small Business 19.505 Rejecting Small Business Administration recommendations. (a) If the contracting officer rejects a recommendation...

  20. 7 CFR 1450.205 - Duration of contracts.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 10 2014-01-01 2014-01-01 false Duration of contracts. 1450.205 Section 1450.205 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP...

  1. 7 CFR 1450.205 - Duration of contracts.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 10 2012-01-01 2012-01-01 false Duration of contracts. 1450.205 Section 1450.205 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP...

  2. 7 CFR 1450.205 - Duration of contracts.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 10 2013-01-01 2013-01-01 false Duration of contracts. 1450.205 Section 1450.205 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP...

  3. 48 CFR 352.219-71 - Mentor-protégé program reporting requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Mentor-protégé program... Clauses 352.219-71 Mentor-protégé program reporting requirements. As prescribed in 319.270-1(b), the Contracting Officer shall insert the following clause: Mentor-Protégé Program Reporting Requirements (January...

  4. 48 CFR 352.219-70 - Mentor-protégé program.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Mentor-protégé program... Mentor-protégé program. As prescribed in 319.270-1(a), the Contracting Officer shall insert the following provision: Mentor-Protégé Program (January 2010) (a) Large business prime contractors serving as mentors in...

  5. Choline as an agonist: determination of its agonistic potency on cholinergic receptors.

    PubMed

    Ulus, I H; Millington, W R; Buyukuysal, R L; Kiran, B K

    1988-07-15

    These experiments examined the potency of choline as a cholinergic agonist at both muscarinic and nicotinic receptors in rat brain and peripheral tissues. Choline stimulated the contraction of isolated smooth muscle preparations of the stomach fundus, urinary bladder and trachea and reduced the frequency of spontaneous contractions of the right atrium at high micromolar and low millimolar concentrations. The potency of choline to elicit a biological response varied markedly among these tissues; EC50 values ranged between 0.41 mM in the fundus to 14.45 mM in the atrium. Choline also displaced [3H]quinuclidinyl benzilate binding in a concentration-dependent manner although, again, its potency varied among different brain regions (Ki = 1.2 to 3.5 mM) and peripheral tissues (Ki = 0.28 to 3.00 mM). Choline exhibited a comparable affinity for nicotinic receptors. It stimulated catecholamine release from the vascularly perfused adrenal gland (EC50 = 1.3 mM) and displaced L-[3H]nicotine binding to membrane preparations of brain and peripheral tissues (Ki = 0.38 to 1.17 mM). However, the concentration of choline required to bind to cholinergic receptors in most tissues was considerably higher than serum levels either in controls (8-13 microM) or following the administration of choline chloride (200 microM). These results clearly demonstrate that choline is a weak cholinergic agonist. Its potency is too low to account for the central nervous system effects produced by choline administration, although the direct activation of cholinergic receptors in several peripheral tissues may explain some of its side effects.

  6. Postprandial gastric antral contractions in patients with gastro-oesophageal reflux disease: a scintigraphic study.

    PubMed

    Barbieri, C L A; Troncon, L E A; Herculano, J R L; Aprile, L R O; Moraes, E R; Secaf, M; Dantas, R O

    2008-05-01

    Disturbed gastric contractility has been found in manometric studies in patients with gastro-oesophageal reflux disease (GORD), but the pathophysiological role of this abnormality is unclear. We aimed at assessing postprandial gastric antral contractions and its relationships with gastric emptying and gastro-oesophageal reflux in GORD patients. Fasted GORD patients (n = 13) and healthy volunteers (n = 13) ingested a liquid meal labelled with 72 MBq of 99mTechnetium-phytate. Gastric images were acquired every 10 min for 2 h, for measuring gastric emptying half time. Dynamic antral scintigraphy (one frame per second), performed for 4 min at 30-min intervals, allowed estimation of both mean dominant frequency and amplitude of antral contractions. In GORD patients (n = 10), acidic reflux episodes occurring 2 h after the ingestion of the same test meal were determined by ambulatory 24-h oesophageal pH monitoring. Gastric emptying was similar in GORD patients and controls (median; range: 82 min; 58-126 vs 80 min; 44-122 min; P = 0.38). Frequency of antral contractions was also similar in both groups (3.1 cpm; 2.8-3.6 vs 3.2 cpm; 2.4-3.8 cpm; P = 0.15). In GORD patients, amplitude of antral contractions was significantly higher than in controls (32.7%; 17-44%vs 23.3%; 16-43%; P = 0.01), and correlated positively with gastric emptying time (R(s) = 0.58; P = 0.03) and inversely with the number of reflux episodes (R(s) = -0.68; P = 0.02). Increased amplitude of postprandial gastric antral contractions in GORD may comprise a compensatory mechanism against delayed gastric emptying and a defensive factor against acidic gastro-oesophageal reflux.

  7. Hydrogen peroxide increases depolarization-induced contraction of mechanically skinned slow twitch fibres from rat skeletal muscles.

    PubMed

    Plant, David R; Lynch, Gordon S; Williams, David A

    2002-03-15

    The effect of exogenous hydrogen peroxide (H(2)O(2)) on excitation-contraction (E-C) coupling and sarcoplasmic reticulum (SR) function was compared in mechanically skinned slow twitch fibres (prepared from the soleus muscles) and fast twitch fibres (prepared from the extensor digitorum longus; EDL muscles) of adult rats. Equilibration (5 min) with 1 mM H(2)O(2) diminished the ability of the Ca(2+)-depleted SR to reload Ca(2+) in both slow (P < 0.01) and fast twitch fibres (P < 0.05) compared to control. Under conditions when all Ca(2+) uptake was prevented, 1 mM H(2)O(2) increased SR Ca(2+) "leak" in fast twitch fibres by 24 +/- 5 % (P < 0.05), but leak was not altered in slow twitch fibres. Treatment with 1 mM H(2)O(2) also increased the peak force of low [caffeine] contracture by approximately 45% in both fibre types compared to control (P < 0.01), which could be partly reversed following treatment with 10 mM dithiothreitol (DTT). The changes in SR function caused by 1 mM H(2)O(2) were associated with an approximately 65% increase in the peak height of depolarization-induced contractile response (DICR) in slow twitch fibres, compared to control (no H(2)O(2); P < 0.05). In contrast, peak contractile force of fast twitch fibres was not altered by 1 mM H(2)O(2) treatment. Equilibration with 5 mM H(2)O(2) induced a spontaneous force response in both slow and fast twitch fibres, which could be partly reversed by 2 min treatment with 10 mM DTT. Peak DICR was also increased approximately 40% by 5 mM H(2)O(2) in slow twitch fibres compared to control (no H(2)O(2); P < 0.05). Our results indicate that exogenous H(2)O(2) increases depolarization-induced contraction of mechanically skinned slow but not fast twitch fibres. The increase in depolarization-induced contraction in slow twitch fibres might be mediated by an increased SR Ca(2+) release during contraction and/or an increase in Ca(2+) sensitivity.

  8. Hydrogen peroxide increases depolarization-induced contraction of mechanically skinned slow twitch fibres from rat skeletal muscles

    PubMed Central

    Plant, David R; Lynch, Gordon S; Williams, David A

    2002-01-01

    The effect of exogenous hydrogen peroxide (H2O2) on excitation-contraction (E-C) coupling and sarcoplasmic reticulum (SR) function was compared in mechanically skinned slow twitch fibres (prepared from the soleus muscles) and fast twitch fibres (prepared from the extensor digitorum longus; EDL muscles) of adult rats. Equilibration (5 min) with 1 mm H2O2 diminished the ability of the Ca2+-depleted SR to reload Ca2+ in both slow (P < 0.01) and fast twitch fibres (P < 0.05) compared to control. Under conditions when all Ca2+ uptake was prevented, 1 mm H2O2 increased SR Ca2+ ‘leak’ in fast twitch fibres by 24 ± 5 % (P < 0.05), but leak was not altered in slow twitch fibres. Treatment with 1 mm H2O2 also increased the peak force of low [caffeine] contracture by ∼45 % in both fibre types compared to control (P < 0.01), which could be partly reversed following treatment with 10 mm dithiothreitol (DTT). The changes in SR function caused by 1 mm H2O2 were associated with an ∼65 % increase in the peak height of depolarization-induced contractile response (DICR) in slow twitch fibres, compared to control (no H2O2; P < 0.05). In contrast, peak contractile force of fast twitch fibres was not altered by 1 mm H2O2 treatment. Equilibration with 5 mm H2O2 induced a spontaneous force response in both slow and fast twitch fibres, which could be partly reversed by 2 min treatment with 10 mm DTT. Peak DICR was also increased ∼40 % by 5 mm H2O2 in slow twitch fibres compared to control (no H2O2; P < 0.05). Our results indicate that exogenous H2O2 increases depolarization-induced contraction of mechanically skinned slow but not fast twitch fibres. The increase in depolarization-induced contraction in slow twitch fibres might be mediated by an increased SR Ca2+ release during contraction and/or an increase in Ca2+ sensitivity. PMID:11897857

  9. 48 CFR 19.202-2 - Locating small business sources.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Locating small business... SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Policies 19.202-2 Locating small business sources. The contracting officer must, to the extent practicable, encourage maximum participation by small business...

  10. 48 CFR 19.202-2 - Locating small business sources.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 1 2012-10-01 2012-10-01 false Locating small business... SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Policies 19.202-2 Locating small business sources. The contracting officer must, to the extent practicable, encourage maximum participation by small business...

  11. 48 CFR 19.202-2 - Locating small business sources.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Locating small business... SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Policies 19.202-2 Locating small business sources. The contracting officer must, to the extent practicable, encourage maximum participation by small business...

  12. 48 CFR 19.202-2 - Locating small business sources.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 1 2014-10-01 2014-10-01 false Locating small business... SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Policies 19.202-2 Locating small business sources. The contracting officer must, to the extent practicable, encourage maximum participation by small business...

  13. 48 CFR 19.202-2 - Locating small business sources.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 1 2013-10-01 2013-10-01 false Locating small business... SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Policies 19.202-2 Locating small business sources. The contracting officer must, to the extent practicable, encourage maximum participation by small business...

  14. Crystal structure of (E)-undec-2-enoic acid.

    PubMed

    Sonneck, Marcel; Peppel, Tim; Spannenberg, Anke; Wohlrab, Sebastian

    2015-06-01

    In the mol-ecule of the title low-melting α,β-unsaturated carb-oxy-lic acid, C11H20O2, the least-squares mean line through the octyl chain forms an angle of 60.10 (13)° with the normal to plane of the acrylic acid fragment (r.m.s. deviation = 0.008 Å). In the crystal, centrosymmetrically related mol-ecules are linked by pairs of O-H⋯O hydrogen bonds into dimers, forming layers parallel to the (041) plane.

  15. Catalyst Bed Instability Within the USFE H2O2/JP-8 Rocket Engine

    NASA Technical Reports Server (NTRS)

    Johnson, Curtis W.; Anderson, William; Ross, Robert; Lyles, G. (Technical Monitor)

    2000-01-01

    Orbital Sciences Corporation has been awarded a contract by NASA's Marshall Space Flight Center, in cooperation with the U.S. Air Force Research Laboratory's Military Space Plane Technology Program Office, for the Upper Stage Flight Experiment (USFE) program. Orbital is designing, developing, and will flight test a new low-cost, 10,000 lbf hydrogen peroxide/ JP-8 pressure fed liquid rocket. During combustion chamber tests at NASA Stennis Space Center (SSC) of the USFE engine, the catalyst bed showed a low frequency instability occurring as the H202 flow reached about 1/3 its design rate. This paper reviews the USFE catalyst bed and combustion chamber and its operation, then discusses the dynamics of the instability. Next the paper describes the dynamic computer model used to recreate the instability. The model was correlated to the SSC test data, and used to investigate possible solutions to the problem. The combustion chamber configuration which solved the instability is shown, and the subsequent stable operation presented.

  16. Lake St. Clair: Storm Wave and Water Level Modeling

    DTIC Science & Technology

    2013-06-01

    R. A. Luettich, C. Dawson, V. J. Cardone , A. T. Cox, M. D. Powell, H. J. Westerink, and H. J. Roberts. 2010. A high resolution coupled riverine flow...Storm Wave and Water Level Modeling 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Tyler J. Hesser

  17. Overview of long pulse H-mode operation on EAST

    NASA Astrophysics Data System (ADS)

    Gong, X.; Garofalo, A. M.; Wan, B.; Li, J.; Qian, J.; Li, E.; Liu, F.; Zhao, Y.; Wang, M.; Xu, H.; EAST Team

    2017-10-01

    The EAST research program aims to demonstrate steady-state long-pulse high-performance H-mode operations with ITER-like poloidal configuration and RF-dominated heating schemes. In the recent experimental campaign, a long pulse fully non-inductive H-mode discharge lasting over 100 seconds using the upper ITER-like tungsten divertor has been achieved in EAST. This scenario used only RF heating and current drive, but also benefitted from an integrated control of the wall conditioning, plasma configuration, divertor heat flux, particle exhaust, impurity management and superconducting coils safety. Maintaining effective coupling of multiple RF heating and current drive sources on EAST is a critical ingredient. This long pulse discharge had good energy confinement, H98,y2 1.1-1.2, and all of the plasma parameters reach a true steady-state. Power balance indicates that the confinement improvement is due partly to a significantly reduced core electron transport inside minor radius rho<0.4. This work was supported by the National Magnetic Confinement Fusion Program of China Contract No. 2015GB10200 and the US Department of Energy Contract No. DE-SC0010685.

  18. The anaerobic degradability of thermoplastic starch: polyvinyl alcohol blends: potential biodegradable food packaging materials.

    PubMed

    Russo, Melissa A L; O'Sullivan, Cathryn; Rounsefell, Beth; Halley, Peter J; Truss, Rowan; Clarke, William P

    2009-03-01

    A systematic study on the anaerobic degradability of a series of starch:polyvinyl alcohol (TPS:PVOH) blends was performed to determine their fate upon disposal in either anaerobic digesters or bioreactor landfills. The aims of the study were to measure the rate and extent of solubilisation of the plastics. The extent of substrate solubilisation on a COD basis reached 60% for a 90:10 (w/w) blend of TPS:PVOH, 40% for 75:25, 30% for 50:50 and 15% for PVOH only. The rate of substrate solubilisation was most rapid for the 90:10 blend (0.041 h(-1)) and decreased with the amount of starch in the blend in the following order 0.034 h(-1)(75:25); 0.023 h(-1)(50:50). The total solids that remained after 900 h were 10 wt.% (90:10); 23 wt.% (75:25); 55 wt.% (50:50); 90 wt.% (0:100). Starch containing substrates produced a higher concentration of volatile fatty acids (VFAs) and biogas, compared to the 0:100 substrate. The major outcome was that PVOH inhibited the degradation of the starch from the blend.

  19. 75 FR 49432 - Impact Aid Programs

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-13

    ... CONTACT. Background The Impact Aid Discretionary Construction Program is authorized under section 8007(b... 2004, when the most recent Impact Aid Discretionary Construction Program regulations were issued, the... Federal Domestic Assistance Number 84.041 Impact Aid Discretionary Construction Program) List of Subjects...

  20. 48 CFR 419.201-71 - Small business coordinators.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Small business... SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Policies 419.201-71 Small business coordinators. The head of the contracting activity (HCA) or a representative of the HCA shall designate in writing a small business...

  1. Avionics Simulation, Development and Software Engineering

    NASA Technical Reports Server (NTRS)

    Francis, Ronald C.; Settle, Gray; Tobbe, Patrick A.; Kissel, Ralph; Glaese, John; Blanche, Jim; Wallace, L. D.

    2001-01-01

    This monthly report summarizes the work performed under contract NAS8-00114 for Marshall Space Flight Center in the following tasks: 1) Purchase Order No. H-32831D, Task Order 001A, GPB Program Software Oversight; 2) Purchase Order No. H-32832D, Task Order 002, ISS EXPRESS Racks Software Support; 3) Purchase Order No. H-32833D, Task Order 003, SSRMS Math Model Integration; 4) Purchase Order No. H-32834D, Task Order 004, GPB Program Hardware Oversight; 5) Purchase Order No. H-32835D, Task Order 005, Electrodynamic Tether Operations and Control Analysis; 6) Purchase Order No. H-32837D, Task Order 007, SRB Command Receiver/Decoder; and 7) Purchase Order No. H-32838D, Task Order 008, AVGS/DART SW and Simulation Support

  2. 10 CFR 600.3 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ..., into which a project is divided for budgeting and funding purposes. Continuation award means an award... project period or renewal thereof. Contract means a written procurement contract executed by a recipient... sharing or matching means that portion of project or programs costs not borne by the Federal Government...

  3. 7 CFR 1430.204 - Requesting benefits.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 10 2014-01-01 2014-01-01 false Requesting benefits. 1430.204 Section 1430.204... Program § 1430.204 Requesting benefits. (a) A request for benefits or contract application, under this... MILC benefits must certify the accuracy and truthfulness of the information in their contract...

  4. 7 CFR 1430.204 - Requesting benefits.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 10 2013-01-01 2013-01-01 false Requesting benefits. 1430.204 Section 1430.204... Program § 1430.204 Requesting benefits. (a) A request for benefits or contract application, under this... MILC benefits must certify the accuracy and truthfulness of the information in their contract...

  5. 7 CFR 1430.204 - Requesting benefits.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 10 2011-01-01 2011-01-01 false Requesting benefits. 1430.204 Section 1430.204... Program § 1430.204 Requesting benefits. (a) A request for benefits or contract application, under this... MILC benefits must certify the accuracy and truthfulness of the information in their contract...

  6. 7 CFR 1430.204 - Requesting benefits.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 10 2012-01-01 2012-01-01 false Requesting benefits. 1430.204 Section 1430.204... Program § 1430.204 Requesting benefits. (a) A request for benefits or contract application, under this... MILC benefits must certify the accuracy and truthfulness of the information in their contract...

  7. 7 CFR 1430.204 - Requesting benefits.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Requesting benefits. 1430.204 Section 1430.204... Program § 1430.204 Requesting benefits. (a) A request for benefits or contract application, under this... MILC benefits must certify the accuracy and truthfulness of the information in their contract...

  8. A role for Na+/H+ exchange in contraction of guinea pig airways by endothelin-1 in vitro.

    PubMed

    Battistini, B; Filep, J G; Cragoe, E J; Fournier, A; Sirois, P

    1991-03-15

    Endothelin-1-induced contractions of guinea pig tracheal and bronchial strips were dose-dependently attenuated by the amiloride analogues 5-(N-ethyl-N-isopropyl)amiloride (EIPA, 1-10 microM) and 5-(N,N-hexamethylene)amiloride (HMA, 1-10 microM). The calculated Ki values for EIPA and HMA were 0.11 +/- 0.02 microM and 0.06 +/- 0.02 microM in the trachea, and 0.28 +/- 0.11 microM and 0.70 +/- 0.25 microM in the bronchus, respectively. These values are in the same order of magnitude as those reported for inhibition of the Na+/H+ exchange in cells. Amiloride (1-10 microM) was ineffective. These data suggest that activation of the Na+/H+ exchange by ET-1 may be involved in mediating its myotropic action in guinea pig airway smooth muscle.

  9. Dachiardite-K, (K2Ca)(Al4Si20O48) · 13H2O, a new zeolite from Eastern Rhodopes, Bulgaria

    NASA Astrophysics Data System (ADS)

    Chukanov, N. V.; Encheva, S.; Petrov, P.; Pekov, I. V.; Belakovskiy, D. I.; Britvin, S. N.; Aksenov, S. M.

    2016-12-01

    Dachiardite-K (IMA No. 2015-041), a new zeolite, is a K-dominant member of the dachiardite series with the idealized formula (K2Ca)(Al4Si20O48) · 13H2O. It occurs in the walls of opal-chalcedony veinlets cutting hydrothermally altered effusive rocks of the Zvezdel paleovolcanic complex near the village of Austa, Momchilgrad Municipality, Eastern Rhodopes, Bulgaria. Chalcedony, opal, dachiardite-Ca, dachiardite-Na, ferrierite-Mg, ferrierite-K, clinoptilolite-Ca, clinoptilolite-K, mordenite, smectite, celadonite, calcite, and barite are associated minerals. The mineral forms radiated aggregates up to 8 mm in diameter consisting of split acicular individuals. Dachiardite-K is white to colorless. Perfect cleavage is observed on (100). D meas = 2.18(2), D calc = 2.169 g/cm3. The IR spectrum is given. Dachiardite-K is biaxial (+), α = 1.477 (calc), β = 1.478(2), γ = 1.481(2), 2 V meas = 65(10)°. The chemical composition (electron microprobe, mean of six point analyses, H2O determined by gravimetric method) is as follows, wt %: 4.51 K2O, 3.27 CaO, 0.41 BaO, 10.36 A12O3, 67.90 SiO2, 13.2 H2O, total is 99.65. The empirical formula is H26.23K1.71Ca1.04Ba0.05Al3.64Si20.24O61. The strongest reflections in the powder X-ray diffraction pattern [ d, Å (I, %) (hkl)] are: 9.76 (24) (001), 8.85 (58) (200), 4.870 (59) (002), 3.807 (16) (202), 3.768 (20) (112, 020), 3.457 (100) (220), 2.966 (17) (602). Dachiardite-K is monoclinic, space gr. C2/m, Cm or C2; the unit cell parameters refined from the powder X-ray diffraction data are: a = 18.670(8), b = 7.511(3), c = 10.231(4) Å, β = 107.79(3)°, V= 1366(1) Å3, Z = 1. The type specimen has been deposited in the Earth and Man National Museum, Sofia, Bulgaria, with the registration number 23927.

  10. Alcohol impairs skeletal muscle protein synthesis and mTOR signaling in a time-dependent manner following electrically stimulated muscle contraction

    PubMed Central

    Lang, Charles H.

    2014-01-01

    Alcohol (EtOH) decreases protein synthesis and mammalian target of rapamycin (mTOR)-mediated signaling and blunts the anabolic response to growth factors in skeletal muscle. The purpose of the current investigation was to determine whether acute EtOH intoxication antagonizes the contraction-induced increase in protein synthesis and mTOR signaling in skeletal muscle. Fasted male mice were injected intraperitoneally with 3 g/kg EtOH or saline (control), and the right hindlimb was electrically stimulated (10 sets of 6 contractions). The gastrocnemius muscle complex was collected 30 min, 4 h, or 12 h after stimulation. EtOH decreased in vivo basal protein synthesis (PS) in the nonstimulated muscle compared with time-matched Controls at 30 min, 4 h, and 12 h. In Control, but not EtOH, PS was decreased 15% after 30 min. In contrast, PS was increased in Control 4 h poststimulation but remained unchanged in EtOH. Last, stimulation increased PS 10% in Control and EtOH at 12 h, even though the absolute rate remained reduced by EtOH. The stimulation-induced increase in the phosphorylation of S6K1 Thr421/Ser424 (20–52%), S6K1 Thr389 (45–57%), and its substrate rpS6 Ser240/244 (37–72%) was blunted by EtOH at 30 min, 4 h, and 12 h. Phosphorylation of 4E-BP1 Ser65 was also attenuated by EtOH (61%) at 4 h. Conversely, phosphorylation of extracellular signal-regulated kinase Thr202/Tyr204 was increased by stimulation in Control and EtOH mice at 30 min but only in Control at 4 h. Our data indicate that acute EtOH intoxication suppresses muscle protein synthesis for at least 12 h and greatly impairs contraction-induced changes in synthesis and mTOR signaling. PMID:25257868

  11. Prime Contract Awards Alphabetically by Contractor, by State or Country, and Place. Part 6. (Dobbins Lou, Inc.-Fahey Machinery Co., Inc.)

    DTIC Science & Technology

    1989-01-01

    0 (-4N4- H0 -.4C.) -. 4 a) () -40) -4 0 ) w 0N %- M C(00) z to IG0 -Iff1 ._40 N I 0 -4 4 5 0 ) L0)) 0 .-. 01-4~ . 0 .4NCJ0) 1-1-4 -4-4 0 )’ ao I -4N... 0 -4 00 0 -n O Olo(c x( c -d0 41r- -C4 N00 to II0 0 - I N N C1,1 0 r -4 -4 r-U 1 0 ... .J0)00N MLI-I0-41 1 00 o0 30- 30 30)mv0v-, 0 a o 5 Qo oN 0114/81 M...100000000000 4I <_1B4.4 110 0D 0n 0n 0 0 00 ofl W I Owl>u if ON 0C Or0N ON" 0 -I

  12. Prime Contract Awards of $100,000 or More by Federal Supply Classification or Service Category and Purchasing Office, FY 88. Part 2. (5610-9999).

    DTIC Science & Technology

    1988-01-01

    EL ..UCw.4< eca t I =- l- E L 3-.C CMUM-4 ɜ -C L) a- = 4z 1 4 4I > M40) .L 4 4 W-4"- M= 0 0 4) OEZ2ZZ MZ U 4)-II & 0 Z 00...8217 000 Mm << -JfCL4 I.- EL i W.--WL0 041 zz - IL ~ ~ ~ ~ WO U W L- CLJf~nnnJ0hU .. 4442 1 o~ ~ fa inn 00. I-0JU t.- m M 0.~. Z.cac co .OLLI-CI o~~ um... El LWWUCLO WOZ30 >0X.4c3 040.UW£0WZ 1-1-Z0. 0 £0-i.- 004 000U.004I00 " m Z>l-I->00wed ~wo xaZ04ZO £0 01-44�£003wm< C.WIJ < >44444444 OIOZW X

  13. Studies of the mechanism of passive anaphylaxis in human airway smooth muscle.

    PubMed

    Davis, C; Jones, T R; Daniel, E E

    1983-07-01

    This investigation was carried out to study allergic contraction of passively sensitized human airway smooth muscle in response to specific antigen challenge. We attempted to determine the role played by histamine, slow reaction substances (SRSs), and cyclooxygenase products in the mediation of this response in tracheal smooth muscle. Tissues were passively sensitized with serum from ragweed-sensitive patients (15 h, 4 degrees C). Subsequent challenge with ragweed antigen produced a slowly developing contraction. The peak contraction to a dose producing a maximal response was 37 +/- 6% of the carbachol maximum. Mepyramine (5 X 10(-6) M) did not alter the contraction. Methylprednisolone (2 X 10(-5) M) attenuated the response to antigen but had no significant effect on the contractile response to arachidonic acid. Indomethacin (5.6-28 X 10(-6) M) enhanced the peak antigen-induced contractions by 25 +/- 11% whereas 5,8,11,14-eicosatetraynoic acid (6.4 X 10(-5) M) selectively attenuated the antigen-induced contraction by 86 +/- 12%. Nordihydroguarietic acid (6-12 X 10(-6) M) attenuated both the antigen plus arachidonate induced responses. FPL-55712 (1-2 X 10(-6) M) antagonized the contractions to antigen. Compound 48/80 and goat antihuman immunoglobulin E produced similar slowly developing contractions in sensitized and in some nonsensitized tissues. These responses, except for an early component of the response to 48/80, were independent of histamine and were reversed by FPL-55712. These findings suggest that arachidonic acid metabolites mediate (slow reacting substances) and modulate (prostaglandins) allergic contraction of human airway smooth muscle while any histamine released contributes little or nothing to the contraction in the larger airways.

  14. 48 CFR 252.209-7009 - Organizational Conflict of Interest-Major Defense Acquisition Program.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Organizational Conflict of... SOLICITATION PROVISIONS AND CONTRACT CLAUSES Text of Provisions And Clauses 252.209-7009 Organizational... clause: ORGANIZATIONAL CONFLICT OF INTEREST—MAJOR DEFENSE ACQUISITION PROGRAM (DEC 2010) (a) Definition...

  15. 48 CFR 1852.246-70 - Mission Critical Space System Personnel Reliability Program.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 6 2011-10-01 2011-10-01 false Mission Critical Space... CONTRACT CLAUSES Texts of Provisions and Clauses 1852.246-70 Mission Critical Space System Personnel Reliability Program. As prescribed in 1846.370(a), insert the following clause: Mission Critical Space System...

  16. 48 CFR 1852.246-70 - Mission Critical Space System Personnel Reliability Program.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 6 2012-10-01 2012-10-01 false Mission Critical Space... CONTRACT CLAUSES Texts of Provisions and Clauses 1852.246-70 Mission Critical Space System Personnel Reliability Program. As prescribed in 1846.370(a), insert the following clause: Mission Critical Space System...

  17. 48 CFR 1852.246-70 - Mission Critical Space System Personnel Reliability Program.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 6 2013-10-01 2013-10-01 false Mission Critical Space... CONTRACT CLAUSES Texts of Provisions and Clauses 1852.246-70 Mission Critical Space System Personnel Reliability Program. As prescribed in 1846.370(a), insert the following clause: Mission Critical Space System...

  18. 48 CFR 1852.246-70 - Mission Critical Space System Personnel Reliability Program.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Mission Critical Space... CONTRACT CLAUSES Texts of Provisions and Clauses 1852.246-70 Mission Critical Space System Personnel Reliability Program. As prescribed in 1846.370(a), insert the following clause: Mission Critical Space System...

  19. 48 CFR 1852.246-70 - Mission Critical Space System Personnel Reliability Program.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 6 2014-10-01 2014-10-01 false Mission Critical Space... CONTRACT CLAUSES Texts of Provisions and Clauses 1852.246-70 Mission Critical Space System Personnel Reliability Program. As prescribed in 1846.370(a), insert the following clause: Mission Critical Space System...

  20. 48 CFR 26.202-1 - Local area set-aside.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Local area set-aside. 26... SOCIOECONOMIC PROGRAMS OTHER SOCIOECONOMIC PROGRAMS Disaster or Emergency Assistance Activities 26.202-1 Local area set-aside. The contracting officer may set aside solicitations to allow only local firms within a...

  1. 48 CFR 252.225-7044 - Balance of Payments Program-Construction Material.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Balance of Payments... AND CONTRACT CLAUSES Text of Provisions And Clauses 252.225-7044 Balance of Payments Program—Construction Material. As prescribed in 225.7503(a), use the following clause: Balance of Payments Program...

  2. 48 CFR 252.225-7044 - Balance of Payments Program-Construction Material.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Balance of Payments... AND CONTRACT CLAUSES Text of Provisions And Clauses 252.225-7044 Balance of Payments Program—Construction Material. As prescribed in 225.7503(a)(1), use the following clause: Balance of Payments Program...

  3. 42 CFR 438.240 - Quality assessment and performance improvement program.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Quality assessment and performance improvement... Performance Improvement Measurement and Improvement Standards § 438.240 Quality assessment and performance improvement program. (a) General rules. (1) The State must require, through its contracts, that each MCO and...

  4. 48 CFR 252.219-7004 - Small business subcontracting plan (test program).

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Small business... AND CONTRACT CLAUSES Text of Provisions And Clauses 252.219-7004 Small business subcontracting plan (test program). As prescribed in 219.708(b)(1)(B), use the following clause: Small Business...

  5. 48 CFR 252.219-7004 - Small business subcontracting plan (test program).

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Small business... AND CONTRACT CLAUSES Text of Provisions And Clauses 252.219-7004 Small business subcontracting plan (test program). As prescribed in 219.708(b)(1)(B), use the following clause: Small Business...

  6. Evaluation of the fetal state by automatic analysis of the heart rate. 2. Deceleration areas and umbilical artery blood pH.

    PubMed

    Tournaire, M; Sturbois, G; Ripoche, A; Le Houezec, R; Breart, G; Chavinie, J; Sureau, C

    1976-01-01

    Fetal heart rate (FHR) deceleration areas were studied to obtain by objective measurement of the FHR, their prognostic value of the new-born state. 1. There is a reasonably good correlation between FHR deceleration areas and UApH (Tab. II). Such a correlation was found by SHELLEY and TIPTON [6] for the whole deceleration area, and by TOURNAIRE et al. [10] for areas divided in a slightly different way. The correlation coefficients between FHR deceleration areas and Apgar score at 1 minute are within a close range of those of the FHR deceleration area and UApH (Tab. I and II). 2. According to the time relationship between deceleration areas and uterine contractions the best correlation coefficient was obtained surprisingly for total, followed by residual and then simultaneous areas. These results agree with those of SHELLEY and TIPTON [6] suggesting that in practice a simple measurement of the whole deceleration area, regardless of the uterine contractions is a sufficient method in evaluating FHR patterns. 3. The special purpose computer built by the BAUDELOCQUE research group can be used on-line, thus in clinical practice. It was not the case for the manual method [4] or the method using a large programmed computer [10]. 4 The evaluation of deceleration areas appears to have several advantages: 1. It provides objective measurements. 2. The unit used is independant of factors such as display speed or scale of the strip-chart. 3. The data is reduced: A few numbers replace the long descriptions of the usual clinical classifications.

  7. Automated evaluation of matrix elements between contracted wavefunctions: A Mathematica version of the FRODO program

    NASA Astrophysics Data System (ADS)

    Angeli, C.; Cimiraglia, R.

    2013-02-01

    A symbolic program performing the Formal Reduction of Density Operators (FRODO), formerly developed in the MuPAD computer algebra system with the purpose of evaluating the matrix elements of the electronic Hamiltonian between internally contracted functions in a complete active space (CAS) scheme, has been rewritten in Mathematica. New version : A program summaryProgram title: FRODO Catalogue identifier: ADV Y _v2_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/ADVY_v2_0.html Program obtainable from: CPC Program Library, Queen's University, Belfast, N. Ireland Licensing provisions: Standard CPC licence, http://cpc.cs.qub.ac.uk/licence/licence.html No. of lines in distributed program, including test data, etc.: 3878 No. of bytes in distributed program, including test data, etc.: 170729 Distribution format: tar.gz Programming language: Mathematica Computer: Any computer on which the Mathematica computer algebra system can be installed Operating system: Linux Classification: 5 Catalogue identifier of previous version: ADV Y _v1_0 Journal reference of previous version: Comput. Phys. Comm. 171(2005)63 Does the new version supersede the previous version?: No Nature of problem. In order to improve on the CAS-SCF wavefunction one can resort to multireference perturbation theory or configuration interaction based on internally contracted functions (ICFs) which are obtained by application of the excitation operators to the reference CAS-SCF wavefunction. The previous formulation of such matrix elements in the MuPAD computer algebra system, has been rewritten using Mathematica. Solution method: The method adopted consists in successively eliminating all occurrences of inactive orbital indices (core and virtual) from the products of excitation operators which appear in the definition of the ICFs and in the electronic Hamiltonian expressed in the second quantization formalism. Reasons for new version: Some years ago we published in this journal a couple of papers [1, 2] hereafter to be referred to as papers I and II, respectively dedicated to the automated evaluation of the matrix elements of the molecular electronic Hamiltonian between internally contracted functions [3] (ICFs). In paper II the program FRODO (after Formal Reduction Of Density Operators) was presented with the purpose of providing working formulas for each occurrence of the ICFs. The original FRODO program was written in the MuPAD computer algebra system [4] and was actively used in our group for the generation of the matrix elements to be employed in the third-order n-electron valence state perturbation theory (NEVPT) [5-8] as well as in the internally contracted configuration interaction (IC-CI) [9]. We present a new version of the program FRODO written in the Mathematica system [10]. The reason for the rewriting of the program lies in the fact that, on the one hand, MuPAD does not seem to be any longer available as a stand-alone system and, on the other hand, Mathematica, due to its ubiquitousness, appears to be increasingly the computer algebra system most widely used nowadays. Restrictions: The program is limited to no more than doubly excited ICFs. Running time: The examples described in the Readme file take a few seconds to run. References: [1] C. Angeli, R. Cimiraglia, Comp. Phys. Comm. 166 (2005) 53. [2] C. Angeli, R. Cimiraglia, Comp. Phys. Comm. 171 (2005) 63. [3] H.-J. Werner, P. J. Knowles, Adv. Chem. Phys. 89 (1988) 5803. [4] B. Fuchssteiner, W. Oevel: http://www.mupad.de Mupad research group, university of Paderborn. Mupad version 2.5.3 for Linux. [5] C. Angeli, R. Cimiraglia, S. Evangelisti, T. Leininger, J.-P. Malrieu, J. Chem. Phys. 114 (2001) 10252. [6] C. Angeli, R. Cimiraglia, J.-P. Malrieu, J. Chem. Phys. 117 (2002) 9138. [7] C. Angeli, B. Bories, A. Cavallini, R. Cimiraglia, J. Chem. Phys. 124 (2006) 054108. [8] C. Angeli, M. Pastore, R. Cimiraglia, Theor. Chem. Acc. 117 (2007) 743. [9] C. Angeli, R. Cimiraglia, Mol. Phys. in press, DOI:10.1080/00268976.2012.689872 [10] http://www.wolfram.com/Mathematica. Mathematica version 8 for Linux.

  8. 77 FR 20622 - N.E.W. Hydro LLC; Notice of Application for Amendment of License and Soliciting Comments, Motions...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-05

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 2744-041; 2744-042] N.E.W....: 2744-041 & 042. c. Date Filed: March 14, 2012. d. Applicant: N.E.W. Hydro LLC. e. Name of Project..., 16 U.S.C. 791(a)-825(r). h. Applicant Contact: Mr. Scott Klabunde, P.O. Box 167, 116 N. State Street...

  9. Carbon Nanotube Based Flexible Supercapacitors

    DTIC Science & Technology

    2011-04-01

    Carbon Nanotube Based Flexible Supercapacitors by Christopher M. Anton and Matthew H. Ervin ARL-TR-5522 April 2011...Carbon Nanotube Based Flexible Supercapacitors Christopher M. Anton and Matthew H. Ervin Sensors and Electron Devices Directorate, ARL...September 2010 4. TITLE AND SUBTITLE Carbon Nanotube Based Flexible Supercapacitors 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT

  10. A Comparison of Electrolytic Capacitors and Supercapacitors for Piezo-Based Energy Harvesting

    DTIC Science & Technology

    2013-07-01

    A Comparison of Electrolytic Capacitors and Supercapacitors for Piezo-Based Energy Harvesting by Matthew H. Ervin, Carlos M. Pereira, John R...Capacitors and Supercapacitors for Piezo-Based Energy Harvesting Matthew H. Ervin Sensors and Electronic Devices Directorate, ARL Carlos M. Pereira... Supercapacitors for Piezo-Based Energy Harvesting 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Matthew H

  11. 10 CFR 455.101 - Borrowing the non-Federal share/title to equipment.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ....101 Section 455.101 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION GRANT PROGRAMS FOR SCHOOLS AND... borrowed funds, such as those provided by loans and performance contracts, even if such financing does not... financing and loan agreements and performance contracts under this section are subject to the requirements...

  12. Rhubarb Monomers Protect Intestinal Mucosal Barrier in Sepsis via Junction Proteins

    PubMed Central

    Wang, Lyu; Cui, Yun-Liang; Zhang, Zhe; Lin, Zhao-Fen; Chen, De-Chang

    2017-01-01

    Background: Leakage of the intestinal mucosal barrier may cause translocation of bacteria, then leading to multiorgan failure. This study hypothesized that rhubarb monomers might protect the gut mucosal barrier in sepsis through junction proteins. Methods: Healthy male Sprague-Dawley rats (weighing 230–250 g) under anesthesia and sedation were subjected to cecal ligation and perforation (CLP). After surgical preparation, rats were randomly assigned to eight groups (n = 6 or 8 each group): sham group (Group A: normal saline gavage); sepsis group (Group B: normal saline gavage); Group C (intraperitoneally, dexamethasone 0.5 mg/kg) immediately after CLP surgery; and rhubarb monomer (100 mg/kg in normal saline)-treated groups (Group D: rhein; Group E: emodin; Group F: 3,8-dihydroxy-1-methyl-anthraquinone-2-carboxylic acid; Group G: 1-O-caffeoyl-2-(4-hydroxy-O-cinnamoyl)-D-glucose; and Group H: daucosterol linoleate). Animals were sacrificed after 24 h. Intestinal histology, lactulose, mannitol concentrations were measured, and zonula occludens (ZO)-1, occludin and claudin-5 transcription (polymerase chain reaction), translation (by Western blot analysis), and expression (by immunohistochemistry) were also measured. Results: Intestinal histology revealed injury to intestinal mucosal villi induced by sepsis in Group B, compared with Group A. Compared with Group A (0.17 ± 0.41), the pathological scores in Groups B (2.83 ± 0.41, P < 0.001), C (1.83 ± 0.41, P < 0.001), D (2.00 ± 0.63, P < 0.001), E (1.83 ± 0.41, P < 0.001), F (1.83 ± 0.75, P < 0.001), G (2.17 ± 0.41, P < 0.001), and H (1.83 ± 0.41, P < 0.001) were significantly increased. Lactulose/mannitol (L/M) ratio in Group B (0.046 ± 0.003) was significantly higher than in Group A (0.013 ± 0.001, P < 0.001) while L/M ratios in Groups C (0.028 ± 0.002, P < 0.001), D (0.029 ± 0.003, P < 0.001), E (0.026 ± 0.003, P < 0.001), F (0.027 ± 0.003, P < 0.001), G (0.030 ± 0.005, P < 0.001), and H (0.026 ± 0.002, P < 0.001) were significantly lower than that in Group B. ZO-1, occludin and claudin-5 transcription, translation, and expression in Group B were significantly lower than that in Group A (P < 0.001), but they were significantly higher in Groups C, D, E, F, G, and H than those in Group B (P < 0.05). Conclusion: Rhubarb monomer treatment ameliorated mucosal damage in sepsis via enhanced transcription, translation, and expression of junction proteins. PMID:28485323

  13. 7 CFR 636.10 - Modifications.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 6 2013-01-01 2013-01-01 false Modifications. 636.10 Section 636.10 Agriculture Regulations of the Department of Agriculture (Continued) NATURAL RESOURCES CONSERVATION SERVICE, DEPARTMENT OF AGRICULTURE LONG TERM CONTRACTING WILDLIFE HABITAT INCENTIVE PROGRAM § 636.10 Modifications. (a) The...

  14. 7 CFR 636.10 - Modifications.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 6 2010-01-01 2010-01-01 false Modifications. 636.10 Section 636.10 Agriculture Regulations of the Department of Agriculture (Continued) NATURAL RESOURCES CONSERVATION SERVICE, DEPARTMENT OF AGRICULTURE LONG TERM CONTRACTING WILDLIFE HABITAT INCENTIVES PROGRAM § 636.10 Modifications. (a) The...

  15. 7 CFR 636.10 - Modifications.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 6 2014-01-01 2014-01-01 false Modifications. 636.10 Section 636.10 Agriculture Regulations of the Department of Agriculture (Continued) NATURAL RESOURCES CONSERVATION SERVICE, DEPARTMENT OF AGRICULTURE LONG TERM CONTRACTING WILDLIFE HABITAT INCENTIVE PROGRAM § 636.10 Modifications. (a) The...

  16. 7 CFR 636.10 - Modifications.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 6 2012-01-01 2012-01-01 false Modifications. 636.10 Section 636.10 Agriculture Regulations of the Department of Agriculture (Continued) NATURAL RESOURCES CONSERVATION SERVICE, DEPARTMENT OF AGRICULTURE LONG TERM CONTRACTING WILDLIFE HABITAT INCENTIVE PROGRAM § 636.10 Modifications. (a) The...

  17. 7 CFR 636.10 - Modifications.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 6 2011-01-01 2011-01-01 false Modifications. 636.10 Section 636.10 Agriculture Regulations of the Department of Agriculture (Continued) NATURAL RESOURCES CONSERVATION SERVICE, DEPARTMENT OF AGRICULTURE LONG TERM CONTRACTING WILDLIFE HABITAT INCENTIVE PROGRAM § 636.10 Modifications. (a) The...

  18. 10 CFR 784.6 - National security considerations for waiver of certain sensitive inventions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... or under any Government contract or subcontract of the Naval Nuclear Propulsion Program or the nuclear weapons programs or other atomic energy defense activities of the Department of Energy, a...) under the Naval Nuclear Propulsion Program or the nuclear weapons programs or other atomic energy...

  19. 10 CFR 784.6 - National security considerations for waiver of certain sensitive inventions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... or under any Government contract or subcontract of the Naval Nuclear Propulsion Program or the nuclear weapons programs or other atomic energy defense activities of the Department of Energy, a...) under the Naval Nuclear Propulsion Program or the nuclear weapons programs or other atomic energy...

  20. The mechanism of bradykinin-induced endothelium-dependent contraction and relaxation in the porcine interlobar renal artery

    PubMed Central

    Ihara, Eikichi; Hirano, Katsuya; Derkach, Dmitry N; Nishimura, Junji; Nawata, Hajime; Kanaide, Hideo

    2000-01-01

    The mechanism of endothelium-dependent regulation of vascular tone of bradykinin was investigated by simultaneously monitoring the changes in the cytosolic Ca2+ concentration and the force of smooth muscle in fura-2-loaded strips of the porcine renal artery with endothelium. During phenylephrine-induced sustained contraction, bradykinin (>3×10−9 M) caused endothelium-dependent triphasic changes in the force of the strips, composed of an initial relaxation, a subsequent transient contraction and a late sustained relaxation. At low concentrations (10−10–10−9 M), bradykinin caused an endothelium-dependent biphasic relaxation with no contraction. A thromboxane A2 (TXA2)/prostaglandin H2 (PGH2) receptor antagonist (10−5 M ONO-3708) completely inhibited, while a TXA2 synthase inhibitor (10−5 M OKY-046) only partially inhibited, the transient contraction induced by bradykinin. Under conditions where the bradykinin-induced contraction was inhibited by ONO-3708 during the phenylephrine-induced contraction, bradykinin induced only a transient relaxation in the presence of NΩ-nitro-L-arginine methyl ester (L-NAME). This transient relaxation was inhibited when the precontraction was initiated by phenylephrine plus 40 mM extracellular K+. The removal of L-NAME from this condition caused a partial reappearance of the initial relaxation and a complete reappearance of the sustained relaxation. In conclusion, bradykinin caused the endothelium-dependent triphasic regulation of vascular tone in the porcine renal artery. The concentrations of bradykinin required to induce a contraction was higher than that required to induce relaxation. Both TXA2 and PGH2 were involved in the bradykinin-induced contraction. The initial relaxation was mediated by nitric oxide and hyperpolarizing factors while the sustained relaxation depended on nitric oxide. PMID:10696094

  1. 48 CFR 45.303 - Use of Government property on independent research and development programs.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Regulations System FEDERAL ACQUISITION REGULATION CONTRACT MANAGEMENT GOVERNMENT PROPERTY Authorizing the Use... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Use of Government property... research and development (IR&D) program, if— (a) Such use will not conflict with the primary use of the...

  2. 48 CFR 45.303 - Use of Government property on independent research and development programs.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Regulations System FEDERAL ACQUISITION REGULATION CONTRACT MANAGEMENT GOVERNMENT PROPERTY Authorizing the Use... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Use of Government property... research and development (IR&D) program, if— (a) Such use will not conflict with the primary use of the...

  3. 42 CFR 460.134 - Minimum requirements for quality assessment and performance improvement program.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ...) Quality of life of participants. (4) Effectiveness and safety of staff-provided and contracted services... 42 Public Health 4 2012-10-01 2012-10-01 false Minimum requirements for quality assessment and... ELDERLY (PACE) PROGRAMS OF ALL-INCLUSIVE CARE FOR THE ELDERLY (PACE) Quality Assessment and Performance...

  4. 42 CFR 460.134 - Minimum requirements for quality assessment and performance improvement program.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...) Quality of life of participants. (4) Effectiveness and safety of staff-provided and contracted services... 42 Public Health 4 2011-10-01 2011-10-01 false Minimum requirements for quality assessment and... ELDERLY (PACE) PROGRAMS OF ALL-INCLUSIVE CARE FOR THE ELDERLY (PACE) Quality Assessment and Performance...

  5. 42 CFR 460.134 - Minimum requirements for quality assessment and performance improvement program.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...) Quality of life of participants. (4) Effectiveness and safety of staff-provided and contracted services... 42 Public Health 4 2010-10-01 2010-10-01 false Minimum requirements for quality assessment and... ELDERLY (PACE) PROGRAMS OF ALL-INCLUSIVE CARE FOR THE ELDERLY (PACE) Quality Assessment and Performance...

  6. 42 CFR 460.134 - Minimum requirements for quality assessment and performance improvement program.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...) Quality of life of participants. (4) Effectiveness and safety of staff-provided and contracted services... 42 Public Health 4 2013-10-01 2013-10-01 false Minimum requirements for quality assessment and... ELDERLY (PACE) PROGRAMS OF ALL-INCLUSIVE CARE FOR THE ELDERLY (PACE) Quality Assessment and Performance...

  7. 42 CFR 460.134 - Minimum requirements for quality assessment and performance improvement program.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...) Quality of life of participants. (4) Effectiveness and safety of staff-provided and contracted services... 42 Public Health 4 2014-10-01 2014-10-01 false Minimum requirements for quality assessment and... ELDERLY (PACE) PROGRAMS OF ALL-INCLUSIVE CARE FOR THE ELDERLY (PACE) Quality Assessment and Performance...

  8. 49 CFR 26.25 - What is the requirement for a liaison officer?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 1 2010-10-01 2010-10-01 false What is the requirement for a liaison officer? 26... Requirements for DBE Programs for Federally-Assisted Contracting § 26.25 What is the requirement for a liaison... Executive Officer concerning DBE program matters. The liaison officer shall be responsible for implementing...

  9. 49 CFR 26.25 - What is the requirement for a liaison officer?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 1 2011-10-01 2011-10-01 false What is the requirement for a liaison officer? 26... Requirements for DBE Programs for Federally-Assisted Contracting § 26.25 What is the requirement for a liaison... Executive Officer concerning DBE program matters. The liaison officer shall be responsible for implementing...

  10. 48 CFR 252.225-7000 - Buy American Act-Balance of Payments Program Certificate.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Buy American Act-Balance... PROVISIONS AND CONTRACT CLAUSES Text of Provisions And Clauses 252.225-7000 Buy American Act—Balance of... Act—Balance of Payments Program Certificate (DEC 2009) (a) Definitions. “Commercially available off...

  11. 49 CFR 26.37 - What are a recipient's responsibilities for monitoring the performance of other program...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 1 2011-10-01 2011-10-01 false What are a recipient's responsibilities for... Contracting § 26.37 What are a recipient's responsibilities for monitoring the performance of other program participants? (a) You must implement appropriate mechanisms to ensure compliance with the part's requirements...

  12. 49 CFR 26.37 - What are a recipient's responsibilities for monitoring the performance of other program...

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 1 2014-10-01 2014-10-01 false What are a recipient's responsibilities for... Contracting § 26.37 What are a recipient's responsibilities for monitoring the performance of other program participants? (a) You must implement appropriate mechanisms to ensure compliance with the part's requirements...

  13. 49 CFR 26.37 - What are a recipient's responsibilities for monitoring the performance of other program...

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 1 2012-10-01 2012-10-01 false What are a recipient's responsibilities for... Contracting § 26.37 What are a recipient's responsibilities for monitoring the performance of other program participants? (a) You must implement appropriate mechanisms to ensure compliance with the part's requirements...

  14. 49 CFR 26.37 - What are a recipient's responsibilities for monitoring the performance of other program...

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 1 2013-10-01 2013-10-01 false What are a recipient's responsibilities for... Contracting § 26.37 What are a recipient's responsibilities for monitoring the performance of other program participants? (a) You must implement appropriate mechanisms to ensure compliance with the part's requirements...

  15. 48 CFR 19.502-2 - Total small business set-asides.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 1 2014-10-01 2014-10-01 false Total small business set... SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Set-Asides for Small Business 19.502-2 Total small business set... exclusively for small business concerns and shall be set aside for small business unless the contracting...

  16. 48 CFR 19.502-2 - Total small business set-asides.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 1 2012-10-01 2012-10-01 false Total small business set... SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Set-Asides for Small Business 19.502-2 Total small business set... contracting officer does not proceed with the small business set-aside and purchases on an unrestricted basis...

  17. 48 CFR 19.502-2 - Total small business set-asides.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Total small business set... SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Set-Asides for Small Business 19.502-2 Total small business set... contracting officer does not proceed with the small business set-aside and purchases on an unrestricted basis...

  18. 48 CFR 19.502-2 - Total small business set-asides.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 1 2013-10-01 2013-10-01 false Total small business set... SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Set-Asides for Small Business 19.502-2 Total small business set... contracting officer does not proceed with the small business set-aside and purchases on an unrestricted basis...

  19. 48 CFR 3052.219-71 - DHS mentor-protégé program.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 7 2010-10-01 2010-10-01 false DHS mentor-protégÃ... CONTRACT CLAUSES Text of Provisions and Clauses 3052.219-71 DHS mentor-protégé program. As prescribed in (HSAR) 48 CFR 3019.708-70(b), insert the following clause: DHS Mentor-Protégé Program (JUN 2006) (a...

  20. Diaphragmatic lymphatic vessel behavior during local skeletal muscle contraction.

    PubMed

    Moriondo, Andrea; Solari, Eleonora; Marcozzi, Cristiana; Negrini, Daniela

    2015-02-01

    The mechanism through which the stresses developed in the diaphragmatic tissue during skeletal muscle contraction sustain local lymphatic function was studied in 10 deeply anesthetized, tracheotomized adult Wistar rats whose diaphragm was exposed after thoracotomy. To evaluate the direct effect of skeletal muscle contraction on the hydraulic intraluminal lymphatic pressures (Plymph) and lymphatic vessel geometry, the maximal contraction of diaphragmatic fibers adjacent to a lymphatic vessel was elicited by injection of 9.2 nl of 1 M KCl solution among diaphragmatic fibers while Plymph was recorded through micropuncture and vessel geometry via stereomicroscopy video recording. In lymphatics oriented perpendicularly to the longitudinal axis of muscle fibers and located at <300 μm from KCl injection, vessel diameter at maximal skeletal muscle contraction (Dmc) decreased to 61.3 ± 1.4% of the precontraction value [resting diameter (Drest)]; however, if injection was at >900 μm from the vessel, Dmc enlarged to 131.1 ± 2.3% of Drest. In vessels parallel to muscle fibers, Dmc increased to 122.8 ± 2.9% of Drest. During contraction, Plymph decreased as much as 22.5 ± 2.6 cmH2O in all submesothelial superficial vessels, whereas it increased by 10.7 ± 5.1 cmH2O in deeper vessels running perpendicular to contracting muscle fibers. Hence, the three-dimensional arrangement of the diaphragmatic lymphatic network seems to be finalized to efficiently exploit the stresses exerted by muscle fibers during the contracting inspiratory phase to promote lymph formation in superficial submesothelial lymphatics and its further propulsion in deeper intramuscular vessels. Copyright © 2015 the American Physiological Society.

  1. Lanthanide contraction effect on crystal structures of lanthanide coordination polymers with cyclohexanocucurbit[6]uril ligand

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zheng, Li-Mei; Liu, Jing-Xin, E-mail: jxliu411@ahut.edu.cn

    A series of compounds based on the macrocyclic ligand cyclohexanocucurbit[6]uril (Cy6Q[6]) with formulas (Ln(H{sub 2}O){sub 6}Cy6Q[6])·2(CdCl{sub 4})·H{sub 3}O·xH{sub 2}O [isomorphous with Ln=La (1), Ce (2), Pr (3) and Nd (4), x=11 (1), 11 (2), 10 (3) and 11 (4)], (Sm(H{sub 2}O){sub 5}Cy6Q[6])·2(CdCl{sub 4})·H{sub 3}O·10H{sub 2}O (5) and (Ln(H{sub 2}O){sub 5}(NO{sub 3})@Cy6Q[6])·2(CdCl{sub 4})·2H{sub 3}O·xH{sub 2}O [isomorphous with Ln=Gd (6), Tb (7) and Dy (8), x=8 (6), 6 (7) and 6 (8)], have been successfully synthesized by the self-assembly of Cy6Q[6] with the corresponding lanthanide nitrate under hydrochloric acid aqueous solution in the presence of CdCl{sub 2}. Single-crystal X-ray diffraction analyses revealedmore » that compounds 1–8 all crystallize in monoclinic space group P2{sub 1}/c, and display 1D coordination polymer structures. The lanthanide contraction effect on the structures of 1–8 has also been investigated and discussed in detail. In contrast, the reaction of Cy6Q[6] with the Ho(NO){sub 3}, Tm(NO){sub 3}, Yb(NO){sub 3} under the same conditions resulted in the compounds 9–11 with formulas Cy6Q[6]·2(CdCl{sub 4})·2H{sub 3}O·xH{sub 2}O [isomorphous with x=10 (9), 10 (10), and 9 (11)], in which no lanthanide cations are observed. The structural difference of these compounds indicates that the Cy6Q[6] may be used in the separation of lanthanide cations. - Graphical abstract: The reaction of cyclohexanocucurbit[6]uril with lanthanide ions (La{sup 3+}, Ce{sup 3+}, Pr{sup 3+}, Nd{sup 3+}, Sm{sup 3+}, Gd{sup 3+}, Tb{sup 3+}, Dy{sup 3+}, Ho{sup 3+}, Tm{sup 3+} and Yb{sup 3+}) under hydrochloric acid in the presence of CdCl{sub 2} resulted in eleven compounds, which demonstrate interesting lanthanide contraction effect and provide a means of separating lanthanide ions. - Highlights: • Eleven compounds of the Ln{sup 3+} with the Cy6Q[6] were synthesized and described. • Compounds 1-8 demonstrate interesting lanthanide contraction effect. • In solid-state structures of compounds 9-11, no lanthanide ions were observed. • This study provides a means of separating lanthanides cations.« less

  2. 7 CFR 634.10 - Applicability.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 6 2013-01-01 2013-01-01 false Applicability. 634.10 Section 634.10 Agriculture Regulations of the Department of Agriculture (Continued) NATURAL RESOURCES CONSERVATION SERVICE, DEPARTMENT OF AGRICULTURE LONG TERM CONTRACTING RURAL CLEAN WATER PROGRAM Project Authorization and Funding § 634.10...

  3. 7 CFR 634.10 - Applicability.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 6 2014-01-01 2014-01-01 false Applicability. 634.10 Section 634.10 Agriculture Regulations of the Department of Agriculture (Continued) NATURAL RESOURCES CONSERVATION SERVICE, DEPARTMENT OF AGRICULTURE LONG TERM CONTRACTING RURAL CLEAN WATER PROGRAM Project Authorization and Funding § 634.10...

  4. 7 CFR 634.10 - Applicability.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 6 2012-01-01 2012-01-01 false Applicability. 634.10 Section 634.10 Agriculture Regulations of the Department of Agriculture (Continued) NATURAL RESOURCES CONSERVATION SERVICE, DEPARTMENT OF AGRICULTURE LONG TERM CONTRACTING RURAL CLEAN WATER PROGRAM Project Authorization and Funding § 634.10...

  5. 7 CFR 634.10 - Applicability.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 6 2010-01-01 2010-01-01 false Applicability. 634.10 Section 634.10 Agriculture Regulations of the Department of Agriculture (Continued) NATURAL RESOURCES CONSERVATION SERVICE, DEPARTMENT OF AGRICULTURE LONG TERM CONTRACTING RURAL CLEAN WATER PROGRAM Project Authorization and Funding § 634.10...

  6. 7 CFR 634.10 - Applicability.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 6 2011-01-01 2011-01-01 false Applicability. 634.10 Section 634.10 Agriculture Regulations of the Department of Agriculture (Continued) NATURAL RESOURCES CONSERVATION SERVICE, DEPARTMENT OF AGRICULTURE LONG TERM CONTRACTING RURAL CLEAN WATER PROGRAM Project Authorization and Funding § 634.10...

  7. Perylene Bisimide Radicals and Biradicals: Synthesis and Molecular Properties.

    PubMed

    Schmidt, David; Son, Minjung; Lim, Jong Min; Lin, Mei-Jin; Krummenacher, Ivo; Braunschweig, Holger; Kim, Dongho; Würthner, Frank

    2015-11-16

    Unprecedented neutral perylene-3,4:9,10-tetracarboxylic acid bisimide (PBI) radicals and biradicals were synthesized by facile chemical oxidation of 4-hydroxyaryl-substituted PBIs. Subsequent characterization by optical and magnetic spectroscopic techniques, as well as quantum chemical calculations, revealed an open-shell singlet biradical ground state for the PBI biradical OS-2(..) (〈s(2)〉=1.2191) with a relatively small singlet-triplet energy gap of 0.041 eV and a large singlet biradical character of y=0.72. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  8. Probabilistic Sensitivity Analysis with Respect to Bounds of Truncated Distributions (PREPRINT)

    DTIC Science & Technology

    2010-04-01

    AFRL-RX-WP-TP-2010-4147 PROBABILISTIC SENSITIVITY ANALYSIS WITH RESPECT TO BOUNDS OF TRUNCATED DISTRIBUTIONS (PREPRINT) H. Millwater and...5a. CONTRACT NUMBER In-house 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 62102F 6. AUTHOR(S) H. Millwater and Y. Feng 5d. PROJECT...Z39-18 1 Probabilistic Sensitivity Analysis with respect to Bounds of Truncated Distributions H. Millwater and Y. Feng Department of Mechanical

  9. Arp 202: a TDG formed in a parent's extended dark matter halo?

    NASA Astrophysics Data System (ADS)

    Scott, T. C.; Lagos, P.; Ramya, S.; Sengupta, C.; Paudel, S.; Sahu, D. K.; Misra, K.; Woo, J.-H.; Sohn, B. W.

    2018-03-01

    We report on H α + [N II] imaging of the Arp 202 interacting pair and its tidal dwarf galaxy (TDG) candidate as well as a GMOS long slit spectrum from the TDG candidate, observed with the Gemini North telescope. Our H α + [N II] imaging reveals the TDG to have an elongated structure, ˜ 1.9 kpc in length with the two principal star-forming knots at either end. Our observations also show the TDG candidate has a recessional VH α ˜ 3032 km s-1, within 100 km s-1 of the parent pair's mean velocity and an oxygen abundance of 12+log(O/H) = 8.10±0.41. The TDG's oxygen abundance is in good agreement with that of a star-forming region in NGC 2719A, one of the parent galaxies, which has an estimated oxygen abundance of 12+log(O/H) = 8.05 ± 0.41. The TDG's VH α and oxygen abundance confirm previous results validating the candidate as a TDG. The absence of detectable emission from the TDG in Spitzer 3.6 and 4.5 μm images together with the lack of absorption lines and weak continuum in the spectrum is consistent with absence the of an old population (≳0.5 Gyr). The location of the TDG within the interaction debris and the absence of indicators of an old stellar population in the TDG is consistent with a scenario in which the TDG is formed from H I stripped from the parent galaxies and within the extended dark matter halo of one of the parents as proposed by Bournaud et al. and Duc et al.

  10. Cisapride stimulates contraction of idiopathic megacolonic smooth muscle in cats.

    PubMed

    Hasler, A H; Washabau, R J

    1997-01-01

    We have previously shown that cisapride, a substituted piperidinyl benzamide, stimulates contraction of healthy feline colonic smooth muscle. The purpose of the present investigation was to determine the effect of cisapride on feline idiopathic megacolonic smooth muscle function. Longitudinal smooth muscle strips from ascending and descending colon were obtained from cats with idiopathic megacolon, suspended in a 1.5 mM Ca(2+)-HEPES buffer solution (37 degrees C, 100% O2, pH 7.4), attached to isometric force transducers, and stretched to optimal muscle length (Lo). Control responses were obtained at each muscle site with acetylcholine (10(-8) to 10(-4) M), substance P (10(-11) to 10(-7) M), or potassium chloride (10 to 80 mM). Muscles were then stimulated with cumulative (10(-9) to 10(-6) M) doses of cisapride in the absence or presence of tetrodotoxin (10(-6) M) and atropine (10(-6) M), or in a 0 calcium HEPES buffer solution. In cats with idiopathic megacolon, cisapride stimulated contractions of longitudinal smooth muscle from both the ascending and the descending colon. Cisapride-induced contractions were similar in magnitude to those induced by substance P and acetylcholine in the ascending colon, but were less than those observed in the descending colon. Cisapride-induced contractions in megacolonic smooth muscle were only partially inhibited by tetrodotoxin and atropine, but were virtually abolished by removal of extracellular calcium. We concluded that cisapride-induced contractions of feline megacolonic smooth muscle are largely smooth muscle mediated and dependent on influx of extracellular calcium. Cisapride-induced contractions in megacolonic smooth muscle are only partially dependent on enteric cholinergic nerves. Thus, cisapride may be useful in the treatment of cats with idiopathic megacolon.

  11. 41 CFR 60-2.17 - Additional required elements of affirmative action programs.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... elements of affirmative action programs. 60-2.17 Section 60-2.17 Public Contracts and Property Management... Action Programs § 60-2.17 Additional required elements of affirmative action programs. In addition to the elements required by § 60-2.10 through § 60-2.16, an acceptable affirmative action program must include the...

  12. 41 CFR 60-2.17 - Additional required elements of affirmative action programs.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... elements of affirmative action programs. 60-2.17 Section 60-2.17 Public Contracts and Property Management... Action Programs § 60-2.17 Additional required elements of affirmative action programs. In addition to the elements required by § 60-2.10 through § 60-2.16, an acceptable affirmative action program must include the...

  13. 41 CFR 60-2.17 - Additional required elements of affirmative action programs.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... elements of affirmative action programs. 60-2.17 Section 60-2.17 Public Contracts and Property Management... Action Programs § 60-2.17 Additional required elements of affirmative action programs. In addition to the elements required by § 60-2.10 through § 60-2.16, an acceptable affirmative action program must include the...

  14. NASA Northeast Regional Technology Transfer Center

    NASA Technical Reports Server (NTRS)

    Dunn, James P.

    2001-01-01

    This report is a summary of the primary activities and metrics for the NASA Northeast Regional Technology Transfer Center, operated by the Center for Technology Commercialization, Inc. (CTC). This report covers the contract period January 1, 2000 - March 31, 2001. This report includes a summary of the overall CTC Metrics, a summary of the Major Outreach Events, an overview of the NASA Business Outreach Program, a summary of the Activities and Results of the Technology into the Zone program, and a Summary of the Major Activities and Initiatives performed by CTC in supporting this contract. Between January 1, 2000 and March 31, 2001, CTC has facilitated 10 license agreements, established 35 partnerships, provided assistance 517 times to companies, and performed 593 outreach activities including participation in 57 outreach events. CTC also assisted Goddard in executing a successful 'Technology into the Zone' program.' CTC is pleased to have performed this contract, and looks forward to continue providing their specialized services in support of the new 5 year RTTC Contract for the Northeast region.

  15. 7 CFR 1415.4 - Program requirements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ..., including the conservation, protection, enhancement, and, if necessary, restoration of the grassland... grazing management plan and any associated conservation plan or restoration agreement. (h) Easements and... conservation plan. (d) The easement or rental contract must grant USDA or its representatives a right of...

  16. Cognitive and Neural Sciences Division 1990 Programs

    DTIC Science & Technology

    1990-08-01

    operator skill acquisition for advanced manufacturing environments. In (W. Karawowski and M. Rahimi, Eds.) Ergonomics of Advanced Manufacturing and...PRINCIPAL INVESTIGATOR: John H. Maunsell University of Rochester Strong School of Medicine and Dentistry (716) 275-2076 R&T PROJECT CODE: 4424242 CONTRACT

  17. Properties of the nuclei and comae of 10 ecliptic comets from Hubble Space Telescope multi-orbit observations

    NASA Astrophysics Data System (ADS)

    Lamy, P. L.; Toth, I.; Weaver, H. A.; A'Hearn, M. F.; Jorda, L.

    2011-04-01

    We report on our on-going effort to detect and characterize cometary nuclei with the Hubble Space Telescope (HST). During cycle 9 (2000 July to 2001 June), we performed multi-orbit observations of 10 ecliptic comets with the Wide Field Planetary Camera 2. Nominally, eight contiguous orbits covering a time interval of ˜11 h were devoted to each comet but a few orbits were occasionally lost. In addition to the standard R band, we could additionally observe four of them in the V band and the two brightest ones in the B band. Time series photometry was used to constrain the size, shape and rotational period of the 10 nuclei. Assuming a geometric albedo of 0.04 for the R band, a linear phase law with a coefficient of 0.04 mag deg-1 and an opposition effect similar to that of comet 19P/Borrelly, we determined the following mean values of the effective radii 47P/Ashbrook-Jackson: 2.86±0.08 km, 61P/Shajn-Schaldach: 0.62±0.02 km, 70P/Kojima: 1.83±0.05 km, 74P/Smirnova-Chernykh: 2.23±0.04 km, 76P/West-Kohoutek-Ikemura: 0.30±0.02 km, 82P/Gehrels 3: 0.69±0.02 km, 86P/Wild 3: 0.41±0.03 km, 87P/Bus: 0.270.01 km, 110P/Hartley 3: 2.15±0.04 km and 147P/Kushida-Muramatsu: 0.21±0.01 km. Because of the limited time coverage (˜11 h), the rotational periods could not be accurately determined, multiple solutions were sometime found and three periods were not constrained at all. Our estimates range from ˜5 to ˜32 h. The lower limits for the ratio a/b of the semi-axis of the equivalent spheroids range from 1.10 (70P) to 2.20 (87P). The four nuclei for which we could measure (V-R) are all significantly redder than the Sun, with 86P/Wild 3 (V-R) = 0.86 ± 0.10 appearing as an ultrared object. We finally determined the dust activity parameter Afρ of their coma in the R band, the colour indices and the reflectivity spectra of four of them. Based on observations made with the NASA/ESA Hubble Space Telescope, obtained at Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy under NASA contract NAS 5-26555.

  18. Submerged fermentation production and characterization of intracellular triterpenoids from Ganoderma lucidum using HPLC-ESI-MS*

    PubMed Central

    Cui, Mei-lin; Yang, Huan-yi; He, Guo-qing

    2015-01-01

    As the main bioactive metabolites of Ganoderma lucidum, triterpenoids have various pharmacological effects. In this paper, the nutritional requirements and culture conditions of a submerged culture of G. lucidum were optimized using the response surface methodology; maximum mycelia biomass and intracellular triterpenoid production reached 1.87 g/100 ml and 93.21 mg/100 ml, respectively, for a culture consisting of wort 4.10% (0.041 g/ml) and yeast extract 1.89% (0.0189 g/ml), pH 5.40. For the first time, we established that wort, which is cheap and abundant, can replace the more commonly used glucose as the sole source of carbohydrate. Using high-performance liquid chromatography-electrospray ionization-mass spectrometry (HPLC-ESI-MS), 10 major ganoderic acids were tentatively identified based on the predominant fragmentation pathways with the elimination of H2O and CO2, as well as cleavage of the D-ring. PMID:26642183

  19. 48 CFR 619.803-70 - Responsibilities of the Office of Small and Disadvantaged Business Utilization (A/SDBU).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Responsibilities of the Office of Small and Disadvantaged Business Utilization (A/SDBU). 619.803-70 Section 619.803-70 Federal Acquisition Regulations System DEPARTMENT OF STATE SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Contracting with the Small Business Administration...

  20. 7 CFR 1410.10 - Restoration of wetlands.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Restoration of wetlands. 1410.10 Section 1410.10... OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS CONSERVATION RESERVE PROGRAM § 1410.10 Restoration of wetlands. (a) An owner or operator who entered into a CRP contract on land that is suitable for...

  1. The Army Study Program.

    DTIC Science & Technology

    1980-10-09

    STUDDIES BY CATEGORY STUDY TITLE SPONSOR NMtTHOO PPA ADM RE:MOTE LINK PRUG DARCOM CONTRACT ADV TECH MODEL FULL DARCON CONTRACT ARMY COMMAND ANDi CONTROL...HOUUSE NUN -RLCURRIN 1 LMANUS DARCON I"-HUSL FF-TH-hLLI TM~k ECUNLNI(. ANALYSIS DARCOM CUNTRALT FOR SFELTKUM ANALYZERS UPLRA1IUN&L FLt)AI/EKPSL TKADL...TECHNULOGY A5 AESM:NT TRADOC bUTH *TEN YEAR INSTRUMENTATIOft ANALYSkIS OCSA ot" PHASE I TERRAIN MODELS DARCOM bUTH lEST CRITLRIA FUOR NUN -IIILLL-K WEAPUN

  2. Military Vision Research Program

    DTIC Science & Technology

    2011-07-01

    accomplishments emanating from this research . • 3 novel computer-based tasks have been developed that measure visual distortions • These tests are based...10-1-0392 TITLE: Military Vision Research Program PRINCIPAL INVESTIGATOR: Dr. Darlene Dartt...CONTRACTING ORGANIZATION: The Schepens Eye Research

  3. Effects of calcium channel blockers on the contractility of the filariid Acanthocheilonema viteae.

    PubMed

    Christ, D; Stillson, T

    1992-01-01

    The role of calcium in muscle contractility was explored in the filarial nematode Acanthocheilonema viteae (Dipetalonema viteae). The parasite was slit open longitudinally and mounted in a smooth-muscle chamber that had been filled with aerated (95% N2/5% CO2) physiological solution at 37 degrees C. Nifedipine (10(-6) M) and cadmium (3 x 10(-5) M) reduced the spontaneous isotonic contractions of A. viteae, whereas verapamil (10(-5) M) and diltiazem (10(-5) M) enhanced them. The effects of nifedipine and verapamil did not appear to be due to the solvent ethanol. All of the drugs reduced the maximal contraction induced by acetylcholine (ACh, 10(-5) M), although nifedipine was the most potent. After the exposure of worm preparations to a calcium-free medium containing ethyleneglycol-bis-(beta-aminoethyl ether)-N,N,N',N'-tetraacetic acid (EGTA, 10(-4) M) for 1 h, application of ACh (10(-5) M) induced a small, transient contraction. Subsequent applications of ACh in this medium had no effect. Thus, the nematode muscle contraction appears to depend on extracellular calcium. Nifedipine, diltiazem, and verapamil could act by reducing the calcium influx across the muscle membrane.

  4. Influence of hormone supplementation to extended semen on artificial insemination, uterine contractions, establishment of a sperm reservoir, and fertility in swine.

    PubMed

    Willenburg, K L; Miller, G M; Rodriguez-Zas, S L; Knox, R V

    2003-04-01

    This study was performed to quantify the effect of hormone addition to semen using a low-fertility model to evaluate its effectiveness and mode of action. At 24 h after the onset of estrus, all gilts received a single low-dose AI (0.5 x 10(9) sperm/80 mL) with no hormone (control, C), estrogens (E, 11.5 microg), PGF2alpha (PG, 5 mg of Lutalyse), or oxytocin (OT, 4 IU), which were then evaluated for semen backflow (n = 48), oviductal and uterine sperm numbers (n = 28), uterine contractions (n = 12), pregnancy rate (PR, n = 120), and number of fetuses (n = 67). In Exp. 1, backflow of semen from the uterus was collected for 8 h after AI, whereas PR and fetuses were assessed at d 25 to 30 after AI. In Exp. 2, backflow was collected and reproductive tracts flushed to determine sperm numbers in the oviducts and the anterior segments of the uterus. In Exp. 3, sows were monitored for uterine contractions for 1 h before AI and for 2 h after AI. In Exp. 1, there was a treatment x time interaction for fluid loss (P < 0.001), but by 8 h after AI, there was no difference in the total volume (70 +/- 1 mL) of semen lost between hormone treatments (85%) compared to controls (90%). There was also a treatment x time interaction (P < 0.05) for number of sperm lost in the backflow (2.1 +/- 0.1 x 10(8)), but by 8 h following AI, there was no effect on total sperm lost for the hormone treatments (38%) compared to C (54%). There was a trend (P = 0.10) for increased numbers of sperm in the uteri of hormone-treated gilts (6.0 +/- 1.3 x 10(4)) compared with C gilts (2.2 +/- 1.3 x 10(4), but there was no effect of treatment on sperm numbers in the oviducts (3.2 +/- 1.3 x 10(4)). Within 0.5 h of AI, there was an increase in the frequency of contractions for PG compared with the other treatments (14.2 vs. 6.3/h, P < 0.005), however there was no effect on amplitude (54 mmHg) or duration (35 s) of contractions. The PR was not influenced by treatment and averaged 54% (P > 0.60), but total numbers of healthy fetuses were increased (P < 0.04) by PG (8.7) and tended (P = 0.06) to be increased for OT (8.4), but not for E (7.2) compared to C (5.8). Hormone addition to semen increased numbers of fetuses and this may be related to an alteration in the pattern of fluid and sperm loss after AI and a tendency for increased numbers of sperm in the anterior segment of the uterus. Therefore, in situations of lowered fertility, hormone addition could be a strategy to limit infertility in swine.

  5. 77 FR 50109 - Medicaid Program; State Allotments for Payment of Medicare Part B Premiums for Qualifying...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-20

    ....45 12,790,778 4,271,524 NA NA 8,519,254 3.5623 1,261,605 NA 11,529,172 Kansas 17 1.17 10,354,439 4....1839 2,190,048 NA 18,518,830 Montana 6 0.41 3,654,508 1,621,995 NA NA 2,032,513 0.8499 300,992 NA 3,353... 26,632,392 5,923,514 16.7259 Need Need Need 5,923,514 26,632,392 Texas 117 8.05 71,262,904 78,314,925...

  6. Graphene Oxide Annealing Procedures for Graphene-Based Supercapacitors

    DTIC Science & Technology

    2015-09-01

    Annealing Procedures for Graphene-Based Supercapacitors by Louis B Levine and Matthew H Ervin Sensors and Electron Devices Directorate, ARL...SUBTITLE Graphene Oxide Annealing Procedures for Graphene-Based Supercapacitors 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6

  7. Magnolol inhibits colonic motility through down-regulation of voltage-sensitive L-type Ca2+ channels of colonic smooth muscle cells in rats.

    PubMed

    Zhang, Man; Zang, Kai-Hong; Luo, Jia-Lie; Leung, Fung-Ping; Huang, Yu; Lin, Cheng-Yuan; Yang, Zhi-Jun; Lu, Ai-Ping; Tang, Xu-Dong; Xu, Hong-Xi; Sung, Joseph Jao-yiu; Bian, Zhao-Xiang

    2013-11-15

    This study aimed to investigate the effect of magnolol (5,5'-diallyl-2,2'-biphenyldiol) on contraction in distal colonic segments of rats and the underlying mechanisms. Colonic segments were mounted in organ baths for isometric force measurement. Whole-cell voltage-sensitive L-type Ca(2+) currents were recorded on isolated single colonic smooth muscle cells using patch-clamp technique. The spontaneous contractions and acetylcholine (ACh)- and Bay K 8644-induced contractions were inhibited by magnolol (3-100 μM). In the presence of Bay K8644 (100 nM), magnolol (10-100 μM) inhibited the contraction induced by 10 μM ACh. By contrast, tetrodotoxin (100 nM) and Nώ-nitro-L-arginine methyl ester (L-NAME 100 μM) did not change the inhibitory effect of magnolol (10 μM). In addition, magnolol (3-100 μM) inhibited the L-type Ca(2+) currents. The present results suggest that magnolol inhibits colonic smooth muscle contraction through downregulating L-type Ca(2+) channel activity. Copyright © 2013 Elsevier GmbH. All rights reserved.

  8. The 2009 Influenza Pandemic: An Overview

    DTIC Science & Technology

    2009-08-06

    36 See, for example, the figure by sanofi pasteur (a flu vaccine manufacturer), “A (H1N1) Vaccine ... vaccine antigen and adjuvant. The funds will be used to place additional orders for bulk H1N1 antigen and adjuvant on existing contracts with sanofi ...national stockpile; launched efforts to develop, manufacture, and test a vaccine ; and enabled waivers of liability and a compensation program in the

  9. Photoinduced Electronic Energy Transfer: Theoretical and Experimental Issues for Light Harvesting Applications

    DTIC Science & Technology

    2013-10-21

    PHOTOINDUCED ELECTRONIC ENERGY TRANSFER - THEORETICAL AND EXPERIMENTAL ISSUES FOR LIGHT HARVESTING APPLICATIONS PAUL BRUMER UNIV OF TORONTO 10/21... Applications 5a. CONTRACT NUMBER 5b. GRANT NUMBER FA9550-10-1-0260 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT...Harvesting Applications Grant Number: FA9550-10-1-0260 Program Manager: Dr. Tatjana Curcic, AFOSR Stated aims of the project

  10. 10 CFR 961.11 - Text of the contract.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... program including information on cost projections, project plans and progress reports. 5. (a) Beginning on...-type documents or computer software (including computer programs, computer software data bases, and computer software documentation). Examples of technical data include research and engineering data...

  11. 10 CFR 961.11 - Text of the contract.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... program including information on cost projections, project plans and progress reports. 5. (a) Beginning on...-type documents or computer software (including computer programs, computer software data bases, and computer software documentation). Examples of technical data include research and engineering data...

  12. 48 CFR 9903.202 - Disclosure requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... ACCOUNTING STANDARDS CONTRACT COVERAGE CAS Program Requirements 9903.202 Disclosure requirements. ... 48 Federal Acquisition Regulations System 7 2010-10-01 2010-10-01 false Disclosure requirements. 9903.202 Section 9903.202 Federal Acquisition Regulations System COST ACCOUNTING STANDARDS BOARD...

  13. 48 CFR 970.2671 - Diversity.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Diversity. 970.2671 Section 970.2671 Federal Acquisition Regulations System DEPARTMENT OF ENERGY AGENCY SUPPLEMENTARY REGULATIONS DOE MANAGEMENT AND OPERATING CONTRACTS Other Socioeconomic Programs 970.2671 Diversity. ...

  14. Effects of in vitro, acute and chronic treatment with fluoxetine on the sympathetic neurotransmission of rat vas deferens.

    PubMed

    Pedroso, Shaista Poppe; de Souza, Bruno Palmieri; Jurkiewicz, Aron; Juriewicz, Neide H; da Silva Junior, Edilson Dantas

    2017-03-01

    It is described that fluoxetine treatment is able to induce ejaculatory disorders. However, the exact mechanism is still not fully understood. Therefore, this study was carried out to further evaluate the anti-ejaculatory effects of fluoxetine, using different approaches (in vitro or in vivo treatments), on the sympathetic neurotransmission of the rat vas deferens. Vas deferens from male Wistar rats were used to check the in vitro effects of fluoxetine 10 -6 M, 3.10 -6 M or 10 -5 M. Animals were also acutely (20mg/kg, i.p. 4h or 24h) or chronically (10mg/kg, i.p., 30days) treated with fluoxetine or drug-free vehicle. The vas deferens from non-treated and treated animals were isolated and mounted in an isolated organ bath for the study of the contractions induced by adrenergic agonists, tyramine, 5-HT, Ca 2+ or electrical field stimulation. In vitro or acute treatment with fluoxetine decreased the contraction induced by agonists, Ca 2+ or electrical field stimulation. The chronic treatment with fluoxetine decreased the contractions induced agonists, tyramine or Ca 2+ , but did not modify the contractions induced by electrical field stimulation. We have shown that in vitro or in vivo fluoxetine treatment is able to alter the sympathetic neurotransmission of the rat vas deferens which could be related to alterations in the calcium signalling. Copyright © 2016 Elsevier B.V. All rights reserved.

  15. Advanced Manufacturing Process for Lower Cost Rechargeable Lithium-ion Batteries for DOD Including the BB2590

    DTIC Science & Technology

    2013-11-30

    Rechargeable Lithium-ion Batteries for DOD Including the BB2590 Contract #SP4701-10-C-0032 Submitted by LithChem Energy (Div. of Retriev...Lithium-ion Batteries for DOD Including the BB2590 5a. CONTRACT NUMBER AP4701-10-C-0032 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER...automated lithium-ion bi-cell production machine to produce lower cost prismatic lithium-ion batteries for the DOD. This machine was completed and

  16. OCCUPATIONAL EDUCATION--PLANNING AND PROGRAMMING. VOLUME TWO.

    ERIC Educational Resources Information Center

    KOTZ, ARNOLD

    ADDITIONAL POSITION PAPERS BASED ON INFORMATION GATHERED IN THE RECONNAISSANCE SURVEYS OF PLANNING AND PROGRAMING IN OCCUPATIONAL EDUCATION, REPORTED IN VOLUME ONE (VT 005 041), ARE PRESENTED. PART IV, CONCERNED WITH PROGRAM STRUCTURE AND BUDGETING AND THEIR RELATION TO THE PLANNING PROCESS, INCLUDES THE PAPERS--(1) "CURRENT POLICIES AND…

  17. Role of reactive oxygen species in contraction-mediated glucose transport in mouse skeletal muscle

    PubMed Central

    Sandström, Marie E; Zhang, Shi-Jin; Bruton, Joseph; Silva, José P; Reid, Michael B; Westerblad, Håkan; Katz, Abram

    2006-01-01

    Exercise increases glucose transport into skeletal muscle via a pathway that is poorly understood. We investigated the role of endogenously produced reactive oxygen species (ROS) in contraction-mediated glucose transport. Repeated contractions increased 2-deoxyglucose (2-DG) uptake roughly threefold in isolated, mouse extensor digitorum longus (fast-twitch) muscle. N-Acetylcysteine (NAC), a non-specific antioxidant, inhibited contraction-mediated 2-DG uptake by ∼50% (P < 0.05 versus control values), but did not significantly affect basal 2-DG uptake or the uptake induced by insulin, hypoxia or 5-aminoimidazole-4-carboxamide-1-β-d-ribofuranoside (AICAR, which mimics AMP-mediated activation of AMP-activated protein kinase, AMPK). Ebselen, a glutathione peroxidase mimetic, also inhibited contraction-mediated 2-DG uptake (by almost 60%, P < 0.001 versus control values). Muscles from mice overexpressing Mn2+-dependent superoxide dismutase, which catalyses H2O2 production from superoxide anions, exhibited a ∼25% higher rate of contraction-mediated 2-DG uptake versus muscles from wild-type control mice (P < 0.05). Exogenous H2O2 induced oxidative stress, as judged by an increase in the [GSSG]/[GSH + GSSG] (reduced glutathione + oxidized glutathione) ratio to 2.5 times control values, and this increase was substantially blocked by NAC. Similarly, NAC significantly attenuated contraction-mediated oxidative stress as judged by measurements of glutathione status and the intracellular ROS level with the fluorescent indicator 5-(and-6)-chloromethyl-2′,7′-dichlorodihydrofluorescein (P < 0.05). Finally, contraction increased AMPK activity and phosphorylation ∼10-fold, and NAC blocked ∼50% of these changes. These data indicate that endogenously produced ROS, possibly H2O2 or its derivatives, play an important role in contraction-mediated activation of glucose transport in fast-twitch muscle. PMID:16777943

  18. Effects of single doses of rabeprazole 20 mg and esomeprazole 40 mg on 24-h intragastric pH in healthy subjects.

    PubMed

    Warrington, Steve; Baisley, Kathy; Dunn, Kate; Boyce, Malcolm; Morocutti, Anna

    2006-09-01

    To compare antisecretory effects of single doses of rabeprazole and esomeprazole. Open, randomised, 2-way crossover, clinical pharmacology study. 24 healthy subjects (10 men; mean age 26.2 y) received a single dose of rabeprazole 20 mg or esomeprazole 40 mg, with a 14-day 'washout'. Intragastric pH was recorded continuously from 24 h before to 24 h after dosing. Mean intragastric pH was higher after esomeprazole than rabeprazole during 0-5 h after dosing (P=0.0001); the reverse was true from 14-24 h (P=0.0002). Mean % time pH>3 and >4 was greater after esomeprazole than rabeprazole during 0-14 h (P=0.041 and 0.044), but the reverse was true during 14-24 h (P=0.0005 and 0.001). In the 0-24 h interval as a whole, there was no difference between treatments in mean pH or % time pH>3 or >4. Single-dose rabeprazole 20 mg was as effective as esomeprazole 40 mg in increasing intragastric pH and maintaining pH>3 and >4, despite the 2-fold difference in dose.

  19. GOT C+ Survey of Transition Clouds in the Inner Galaxy

    NASA Astrophysics Data System (ADS)

    Velusamy, Thangasamy; Langer, W. D.; Pineda, J. L.; Goldsmith, P. F.; Li, D.; Yorke, H. W.

    2010-05-01

    To understand star formation and the lifecycle of the interstellar gas we need detailed information about the transition of diffuse atomic to molecular clouds. The C+ line at 1.9 THz traces a so-far poorly studied stage in cloud evolution - the transitional clouds going from atomic HI to molecular H2 The transition cloud phase, which is difficult to observe in HI and CO alone, may be best characterized via CII emission or absorption. Here we present the first results on transition clouds along a few representative lines of sight in the inner Galaxy from longitude 325 degrees to 10 degrees, observed under the GOT C+ program, a HIFI Herschel Key Project to study the diffuse ISM. We can separate out the different ISM components along each line of sight by comparisons of the high spectral resolution ( 1 km/s) and high sensitivity (rms 0.1 K to 0.2 K) HIFI data on C+ with HI, 12CO, and 13CO spectra. These observations are being carried out with the Herschel Space Observatory. This research was conducted at the Jet Propulsion Laboratory, California Institute of Technology under contract with the National Aeronautics and Space Administration. JLP is supported under the NASA Postdoctoral Program at JPL, Caltech, administered by Oak Ridge Associated Universities through a contract with NASA.

  20. Cardiovascular response to prescribed detraining among recreational athletes.

    PubMed

    Pedlar, Charles R; Brown, Marcel G; Shave, Robert E; Otto, James M; Drane, Aimee; Michaud-Finch, Jennifer; Contursi, Miranda; Wasfy, Meagan M; Hutter, Adolph; Picard, Michael H; Lewis, Gregory D; Baggish, Aaron L

    2018-04-01

    Exercise-induced cardiac remodeling (EICR) and the attendant myocardial adaptations characteristic of the athlete's heart may regress during periods of exercise reduction or abstinence. The time course and mechanisms underlying this reverse remodeling, specifically the impact of concomitant plasma volume (PV) contraction on cardiac chamber size, remain incompletely understood. We therefore studied recreational runners ( n = 21, age 34 ± 7 yr; 48% male) who completed an 18-wk training program (~7 h/wk) culminating in the 2016 Boston Marathon after which total exercise exposure was confined to <2 h/wk (no single session >1 h) for 8 wk. Cardiac structure and function, exercise capacity, and PV were assessed at peak fitness (10-14 days before) and at 4 wk and 8 wk postmarathon. Mixed linear modeling adjusting for age, sex, V̇o 2peak , and marathon finish time was used to compare data across time points. Physiological detraining was evidenced by serial reductions in treadmill performance. Two distinct phases of myocardial remodeling and hematological adaptation were observed. After 4 wk of detraining, there were significant reductions in PV (Δ -6.0%, P < 0.01), left ventricular (LV) wall thickness (Δ -8.1%, <0.05), LV mass (Δ -10.3%, P < 0.001), and right atrial area (Δ -8.2%, P < 0.001). After 8 wk of detraining, there was a significant reduction in right ventricle chamber size (end-diastolic area Δ = -8.0%, P < 0.05) without further concomitant reductions in PV or LV wall thickness. Abrupt reductions in exercise training stimulus result in a structure-specific time course of reverse cardiac remodeling that occurs largely independently of PV contraction. NEW & NOTEWORTHY Significant reverse cardiac remodeling, previously documented among competitive athletes, extends to recreational runners and occurs with a distinct time course. Initial reductions in plasma volume and left ventricular (LV) mass, driven by reductions in wall thickness, are followed by contraction of the right ventricle. Consistent with data from competitive athletes, LV chamber volumes appear less responsive to detraining and may be a more permanent adaptation to sport.

  1. 41 CFR 109-45.1002-3 - Precious metals recovery program monitor.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... program monitor. 109-45.1002-3 Section 109-45.1002-3 Public Contracts and Property Management Federal... UTILIZATION AND DISPOSAL 45-SALE, ABANDONMENT, OR DESTRUCTION OF PERSONAL PROPERTY 45.10-Recovery of Precious Metals § 109-45.1002-3 Precious metals recovery program monitor. The DPMO shall be the precious metals...

  2. 48 CFR 1522.608 - Procedures.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Procedures. 1522.608 Section 1522.608 Federal Acquisition Regulations System ENVIRONMENTAL PROTECTION AGENCY SOCIOECONOMIC PROGRAMS APPLICATION OF LABOR LAWS TO GOVERNMENT ACQUISITIONS Walsh-Healey Public Contracts Act 1522.608...

  3. 48 CFR 570.602 - GSAR solicitation provisions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false GSAR solicitation provisions. 570.602 Section 570.602 Federal Acquisition Regulations System GENERAL SERVICES ADMINISTRATION SPECIAL CONTRACTING PROGRAMS ACQUIRING LEASEHOLD INTERESTS IN REAL PROPERTY Solicitation Provisions and...

  4. 48 CFR 1523.703 - Policies and procedures.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Policies and procedures. 1523.703 Section 1523.703 Federal Acquisition Regulations System ENVIRONMENTAL PROTECTION AGENCY SOCIOECONOMIC PROGRAMS ENVIRONMENTAL, CONSERVATION, OCCUPATIONAL SAFETY, AND DRUG-FREE WORKPLACE Contracting for...

  5. 48 CFR 570.106 - Publicizing/Advertising.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Publicizing/Advertising. 570.106 Section 570.106 Federal Acquisition Regulations System GENERAL SERVICES ADMINISTRATION SPECIAL CONTRACTING PROGRAMS ACQUIRING LEASEHOLD INTERESTS IN REAL PROPERTY General 570.106 Publicizing/Advertising...

  6. 48 CFR 1330.202 - Disclosure requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Disclosure requirements. 1330.202 Section 1330.202 Federal Acquisition Regulations System DEPARTMENT OF COMMERCE GENERAL CONTRACTING REQUIREMENTS COST ACCOUNTING STANDARDS ADMINISTRATION CAS Program Requirements 1330.202 Disclosure...

  7. 48 CFR 1430.202 - Disclosure requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Disclosure requirements. 1430.202 Section 1430.202 Federal Acquisition Regulations System DEPARTMENT OF THE INTERIOR GENERAL CONTRACTING REQUIREMENTS COST ACCOUNTING STANDARDS ADMINISTRATION CAS Program Requirements 1430.202 Disclosure...

  8. 48 CFR 30.202 - Disclosure requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Disclosure requirements. 30.202 Section 30.202 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION GENERAL CONTRACTING REQUIREMENTS COST ACCOUNTING STANDARDS ADMINISTRATION CAS Program Requirements 30.202 Disclosure...

  9. 48 CFR 430.202 - Disclosure requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Disclosure requirements. 430.202 Section 430.202 Federal Acquisition Regulations System DEPARTMENT OF AGRICULTURE GENERAL CONTRACTING REQUIREMENTS COST ACCOUNTING STANDARDS ADMINISTRATION CAS Program Requirements 430.202 Disclosure...

  10. 48 CFR 570.102 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Definitions. 570.102 Section 570.102 Federal Acquisition Regulations System GENERAL SERVICES ADMINISTRATION SPECIAL CONTRACTING PROGRAMS ACQUIRING LEASEHOLD INTERESTS IN REAL PROPERTY General 570.102 Definitions. Acquisition means the...

  11. 48 CFR 30.202 - Disclosure requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Disclosure requirements. 30.202 Section 30.202 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION GENERAL CONTRACTING REQUIREMENTS COST ACCOUNTING STANDARDS ADMINISTRATION CAS Program Requirements 30.202 Disclosure...

  12. 48 CFR 1330.202 - Disclosure requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Disclosure requirements. 1330.202 Section 1330.202 Federal Acquisition Regulations System DEPARTMENT OF COMMERCE GENERAL CONTRACTING REQUIREMENTS COST ACCOUNTING STANDARDS ADMINISTRATION CAS Program Requirements 1330.202 Disclosure...

  13. 48 CFR 1430.202 - Disclosure requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Disclosure requirements. 1430.202 Section 1430.202 Federal Acquisition Regulations System DEPARTMENT OF THE INTERIOR GENERAL CONTRACTING REQUIREMENTS COST ACCOUNTING STANDARDS ADMINISTRATION CAS Program Requirements 1430.202 Disclosure...

  14. 48 CFR 430.202 - Disclosure requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 4 2011-10-01 2011-10-01 false Disclosure requirements. 430.202 Section 430.202 Federal Acquisition Regulations System DEPARTMENT OF AGRICULTURE GENERAL CONTRACTING REQUIREMENTS COST ACCOUNTING STANDARDS ADMINISTRATION CAS Program Requirements 430.202 Disclosure...

  15. 48 CFR 2427.305 - Administration of patent rights clauses.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 6 2011-10-01 2011-10-01 false Administration of patent... AND URBAN DEVELOPMENT SOCIOECONOMIC PROGRAMS PATENTS, DATA, AND COPYRIGHTS Patent Rights Under Government Contracts 2427.305 Administration of patent rights clauses. ...

  16. 48 CFR 2427.305 - Administration of patent rights clauses.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Administration of patent... AND URBAN DEVELOPMENT SOCIOECONOMIC PROGRAMS PATENTS, DATA, AND COPYRIGHTS Patent Rights Under Government Contracts 2427.305 Administration of patent rights clauses. ...

  17. 48 CFR 2427.305 - Administration of patent rights clauses.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 6 2013-10-01 2013-10-01 false Administration of patent... AND URBAN DEVELOPMENT SOCIOECONOMIC PROGRAMS PATENTS, DATA, AND COPYRIGHTS Patent Rights Under Government Contracts 2427.305 Administration of patent rights clauses. ...

  18. 48 CFR 2427.305 - Administration of patent rights clauses.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 6 2014-10-01 2014-10-01 false Administration of patent... AND URBAN DEVELOPMENT SOCIOECONOMIC PROGRAMS PATENTS, DATA, AND COPYRIGHTS Patent Rights Under Government Contracts 2427.305 Administration of patent rights clauses. ...

  19. 48 CFR 2427.305 - Administration of patent rights clauses.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 6 2012-10-01 2012-10-01 false Administration of patent... AND URBAN DEVELOPMENT SOCIOECONOMIC PROGRAMS PATENTS, DATA, AND COPYRIGHTS Patent Rights Under Government Contracts 2427.305 Administration of patent rights clauses. ...

  20. 48 CFR 825.870 - Technical assistance.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Technical assistance. 825... SOCIOECONOMIC PROGRAMS FOREIGN ACQUISITION Other International Agreements and Coordination 825.870 Technical assistance. Contracting officers may obtain technical information or guidance on international agreements and...

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