Project ELaNa and NASA's CubeSat Initiative

NASA Technical Reports Server (NTRS)

Skrobot, Garrett Lee

2010-01-01

This slide presentation reviews the NASA program to use expendable lift vehicles (ELVs) to launch nanosatellites for the purpose of enhancing educational research. The Education Launch of Nanosatellite (ELaNa) project, run out of the Launch Services Program is requesting proposals for CubeSat type payload to provide information that will aid or verify NASA Projects designs while providing higher educational research

Drug Control: Additional Performance Information Is Needed to Oversee the National Guard’s State Counterdrug Program

DTIC Science & Technology

2015-10-01

analysis General support a. Domestic cannabis suppression and eradication b. Transportation Reconnaissance and observation a. Ground...mapping analysis n/a n/a n/a 433 433 Training or administrative 5,321 1,431 3,650 2,878 13,281 General support Cannabis eradication 23,679

Progress in the Diagnosis of Appendicitis: A Report from Washington State’s Surgical Care and Outcomes Assessment Program (SCOAP)

PubMed Central

Drake, Frederick Thurston; Florence, Michael G.; Johnson, Morris G.; Jurkovich, Gregory J.; Kwon, Steve; Schmidt, Zeila; Thirlby, Richard C.; Flum, David R.

2012-01-01

BACKGROUND and OBJECTIVES Studies suggest that CT and US can effectively diagnose and rule-out appendicitis, safely reducing negative appendectomies (NA); however, some within the surgical community remain reluctant to add imaging to clinical evaluation of patients with suspected appendicitis. The Surgical Care and Outcomes Assessment Program (SCOAP) is a physician-led quality initiative that monitors performance by benchmarking processes of care and outcomes. Since 2006, accurate diagnosis of appendicitis has been a priority for SCOAP. The objective of this study was to evaluate the association between imaging and NA in the general community. METHODS Data were collected prospectively for consecutive appendectomy patients (age > 15) at nearly 60 hospitals. SCOAP data are obtained directly from clinical records, including radiology, operative, and pathology reports. Multivariate logistic regression models were used to examine the association between imaging and NA. Tests for trends over time were also conducted. RESULTS Among 19,327 patients (47.9% female) who underwent appendectomy, 5.4% had NA. Among patients who were imaged, frequency of NA was 4.5%, whereas among those who were not imaged, NA was 15.4% (p < 0.001). This association was consistent for males (3% vs. 10%, p < 0.001) and for reproductive-age females (6.9% vs. 24.7%, p < 0.001). In a multivariate model adjusted for age, sex, and WBC, odds of NA for patients not imaged were 3.7 times the odds for those who received imaging (95%CI 3.0 – 4.4). Among SCOAP hospitals, use of imaging increased and NA decreased significantly over time; frequency of perforation was unchanged. CONCLUSIONS Patients who were not imaged during work-up for suspected appendicitis had over three times the odds of NA as those who were imaged. Routine imaging in the evaluation of patients suspected to have appendicitis can safely reduce unnecessary operations. Programs such as SCOAP improve care through peer-led, benchmarked practice change. PMID:22964731

Targeting histone abnormality in triple negative breast cancer

DTIC Science & Technology

2017-08-01

PROGRAM ELEMENT NUMBER N/A 6. AUTHOR(S) 5d. PROJECT NUMBER N/A Steffi Oesterreich, PhD 5e. TASK NUMBER N/A E -Mail: oesterreichs@upmc.edu 5f...AVAILABILITY STATEMENT Approved for Public Release; Distribution Unlimited 13. SUPPLEMENTARY NOTES N/A 14. ABSTRACT During this funding period, Dr. Nancy E ...Technologies or techniques Nothing to Report (d) Inventions, patent applications, and/or licenses Nothing to Report ( e ) Other Products Nothing to

40 CFR Table 1 to Subpart Ggg of... - General Provisions Applicability to Subpart GGG

Code of Federal Regulations, 2011 CFR

2011-07-01

... Yes 63.1(d) [Reserved] NA 63.1(e) Applicability of permit program before a relevant standard has been...) [Reserved] NA 63.5(b)(3) New construction/reconstruction Yes Except for changes and additions authorized... Yes 63.5(c) [Reserved] NA 63.5(d) Application for approval of construction/reconstruction Yes Except...

40 CFR Table 1 to Subpart Ggg of... - General Provisions Applicability to Subpart GGG

Code of Federal Regulations, 2010 CFR

2010-07-01

... Yes 63.1(d) [Reserved] NA 63.1(e) Applicability of permit program before a relevant standard has been...) [Reserved] NA 63.5(b)(3) New construction/reconstruction Yes Except for changes and additions authorized... Yes 63.5(c) [Reserved] NA 63.5(d) Application for approval of construction/reconstruction Yes Except...

Physics at the SPS.

PubMed

Gatignon, L

2018-05-01

The CERN Super Proton Synchrotron (SPS) has delivered a variety of beams to a vigorous fixed target physics program since 1978. In this paper, we restrict ourselves to the description of a few illustrative examples in the ongoing physics program at the SPS. We will outline the physics aims of the COmmon Muon Proton Apparatus for Structure and Spectroscopy (COMPASS), north area 64 (NA64), north area 62 (NA62), north area 61 (NA61), and advanced proton driven plasma wakefield acceleration experiment (AWAKE). COMPASS studies the structure of the proton and more specifically of its spin. NA64 searches for the dark photon A', which is the messenger for interactions between normal and dark matter. The NA62 experiment aims at a 10% precision measurement of the very rare decay K + → π + νν. As this decay mode can be calculated very precisely in the Standard Model, it offers a very good opportunity to look for new physics beyond the Standard Model. The NA61/SHINE experiment studies the phase transition to Quark Gluon Plasma, a state in which the quarks and gluons that form the proton and the neutron are de-confined. Finally, AWAKE investigates proton-driven wake field acceleration: a promising technique to accelerate electrons with very high accelerating gradients. The Physics Beyond Colliders study at CERN is paving the way for a significant and diversified continuation of this already rich and compelling physics program that is complementary to the one at the big colliders like the Large Hadron Collider.

Physics at the SPS

NASA Astrophysics Data System (ADS)

Gatignon, L.

2018-05-01

The CERN Super Proton Synchrotron (SPS) has delivered a variety of beams to a vigorous fixed target physics program since 1978. In this paper, we restrict ourselves to the description of a few illustrative examples in the ongoing physics program at the SPS. We will outline the physics aims of the COmmon Muon Proton Apparatus for Structure and Spectroscopy (COMPASS), north area 64 (NA64), north area 62 (NA62), north area 61 (NA61), and advanced proton driven plasma wakefield acceleration experiment (AWAKE). COMPASS studies the structure of the proton and more specifically of its spin. NA64 searches for the dark photon A', which is the messenger for interactions between normal and dark matter. The NA62 experiment aims at a 10% precision measurement of the very rare decay K+ → π+νν. As this decay mode can be calculated very precisely in the Standard Model, it offers a very good opportunity to look for new physics beyond the Standard Model. The NA61/SHINE experiment studies the phase transition to Quark Gluon Plasma, a state in which the quarks and gluons that form the proton and the neutron are de-confined. Finally, AWAKE investigates proton-driven wake field acceleration: a promising technique to accelerate electrons with very high accelerating gradients. The Physics Beyond Colliders study at CERN is paving the way for a significant and diversified continuation of this already rich and compelling physics program that is complementary to the one at the big colliders like the Large Hadron Collider.

Military Ethnomusicology: Understanding the Positive Impact of Music on the United States Military within the American Society

DTIC Science & Technology

2010-03-22

Understanding the Positive Impact of Music N/A on the United States Military within the American Society. Sb. GRANT NUMBER N/A Sc. PROGRAM ELEMENT NUMBER N...AGENCY REPORT NUMBER N/A 12. DISTRIBUTION AVAILABILITY STATEMENT Unlimited 13. SUPPLEMENTARY NOTES N/A 14.ABSTRACT Music is universal to every...human society. Martial music has played an integral, positive role for the military. Music helps unite societies and their military forces in times of

Simulations of Laboratory Astrophysics Experiments using the CRASH code

NASA Astrophysics Data System (ADS)

Trantham, Matthew; Kuranz, Carolyn; Manuel, Mario; Keiter, Paul; Drake, R. P.

2014-10-01

Computer simulations can assist in the design and analysis of laboratory astrophysics experiments. The Center for Radiative Shock Hydrodynamics (CRASH) at the University of Michigan developed a code that has been used to design and analyze high-energy-density experiments on OMEGA, NIF, and other large laser facilities. This Eulerian code uses block-adaptive mesh refinement (AMR) with implicit multigroup radiation transport, electron heat conduction and laser ray tracing. This poster/talk will demonstrate some of the experiments the CRASH code has helped design or analyze including: Kelvin-Helmholtz, Rayleigh-Taylor, imploding bubbles, and interacting jet experiments. This work is funded by the Predictive Sciences Academic Alliances Program in NNSA-ASC via Grant DEFC52-08NA28616, by the NNSA-DS and SC-OFES Joint Program in High-Energy-Density Laboratory Plasmas, Grant Number DE-NA0001840, and by the National Laser User Facility Program, Grant Number DE-NA0000850.

Recent Results and the Future of the NA61/SHINE Strong Interactions Program

NASA Astrophysics Data System (ADS)

Łysakowski, B.

NA61/SHINE is a fixed target experiment at the CERN Super-Proton- Synchrotron. The main goals of the experiment are to discover the critical point of strongly interacting matter and study the properties of the onset of deconfnement. In order to reach these goals the collaboration studies hadron production properties in nucleus-nucleus, proton-proton and proton-nucleus interactions. In this talk, recent results on particle production in p+p interactions, as well as Be+Be and Ar+Sc collisions in the SPS energy range are reviewed. The results are compared with available world data. The future of the NA61/SHINE scientifc program is also presented.

AqSo_NaCl: Computer program to calculate p-T-V-x properties in the H2O-NaCl fluid system applied to fluid inclusion research and pore fluid calculation

NASA Astrophysics Data System (ADS)

Bakker, Ronald J.

2018-06-01

The program AqSo_NaCl has been developed to calculate pressure - molar volume - temperature - composition (p-V-T-x) properties, enthalpy, and heat capacity of the binary H2O-NaCl system. The algorithms are designed in BASIC within the Xojo programming environment, and can be operated as stand-alone project with Macintosh-, Windows-, and Unix-based operating systems. A series of ten self-instructive interfaces (modules) are developed to calculate fluid inclusion properties and pore fluid properties. The modules may be used to calculate properties of pure NaCl, the halite-liquidus, the halite-vapourus, dew-point and bubble-point curves (liquid-vapour), critical point, and SLV solid-liquid-vapour curves at temperatures above 0.1 °C (with halite) and below 0.1 °C (with ice or hydrohalite). Isochores of homogeneous fluids and unmixed fluids in a closed system can be calculated and exported to a.txt file. Isochores calculated for fluid inclusions can be corrected according to the volumetric properties of quartz. Microthermometric data, i.e. dissolution temperatures and homogenization temperatures, can be used to calculated bulk fluid properties of fluid inclusions. Alternatively, in the absence of total homogenization temperature the volume fraction of the liquid phase in fluid inclusions can be used to obtain bulk properties.

Antenatal glucocorticoid treatment alters Na+ uptake in renal proximal tubule cells from adult offspring in a sex-specific manner.

PubMed

Su, Yixin; Bi, Jianli; Pulgar, Victor M; Figueroa, Jorge; Chappell, Mark; Rose, James C

2015-06-01

We have shown a sex-specific effect of fetal programming on Na(+) excretion in adult sheep. The site of this effect in the kidney is unknown. Therefore, we tested the hypothesis that renal proximal tubule cells (RPTCs) from adult male sheep exposed to betamethasone (Beta) before birth have greater Na(+) uptake than do RPTCs from vehicle-exposed male sheep and that RPTCs from female sheep similarly exposed are not influenced by antenatal Beta. In isolated RPTCs from 1- to 1.5-yr-old male and female sheep, we measured Na(+) uptake under basal conditions and after stimulation with ANG II. To gain insight into the mechanisms involved, we also measured nitric oxide (NO) levels, ANG II receptor mRNA levels, and expression of Na(+)/H(+) exchanger 3. Basal Na(+) uptake increased more in cells from Beta-exposed male sheep than in cells from vehicle-exposed male sheep (400% vs. 300%, P < 0.00001). ANG II-stimulated Na(+) uptake was also greater in cells from Beta-exposed males. Beta exposure did not increase Na(+) uptake by RPTCs from female sheep. NO production was suppressed more by ANG II in RPTCs from Beta-exposed males than in RPTCs from either vehicle-exposed male or female sheep. Our data suggest that one site of the sex-specific effect of Beta-induced fetal programming in the kidney is the RPTC and that the enhanced Na(+) uptake induced by antenatal Beta in male RPTCs may be related to the suppression of NO in these cells. Copyright © 2015 the American Physiological Society.

The Key to Life Nutrition Program: results from a community-based dietary sodium reduction trial

PubMed Central

Robare, Joseph F; Milas, N Carole; Bayles, Constance M; Williams, Kathy; Newman, Anne B; Lovalekar, Mita T; Boudreau, Robert; McTigue, Kathleen; Albert, Steven M; Kuller, Lewis H

2016-01-01

Objective Evaluation of a dietary Na reduction trial in a community setting. Design Community-based randomized trial. Ten-week nutrition intervention activities focused on lifestyle modification to decrease dietary Na intake, under the supervision of a registered dietitian. Twenty-four hour urine specimens were collected at baseline and follow-up visits to determine 24 h urinary Na excretion. Setting The University of Pittsburgh Center for Healthy Aging, Key to Life Nutrition Program. Subjects Hypertensive adults at least 65 years of age. Results Mean age of participants was 75 years. Twenty-four hour mean urinary Na excretion at baseline was 3174 mg/d. This reduced to 2944 mg/d (P = 0·30) and 2875 mg/d (P ≤ 0·03) at 6-and 12-month follow-ups, respectively. In a sub-sample (urine volume of ≥ 1000 ml, baseline to 12 months), mean urinary Na excretion decreased from 3220 mg/d to 2875 mg/d (P ≤ 0·02). Conclusions Significant reductions in mean 24 h urinary Na were reported, but results fell short of the recommended guidelines of 1500 mg/d for at-risk individuals. Our results reiterate the difficulty in implementing these guidelines in community-based programmes. More aggressive public health efforts, food industry support and health policy changes are needed to decrease Na levels in older adults to the recommended guidelines. PMID:19781124

Visiting Scholars Program | FNLCR Staging

Cancer.gov

The Visiting Scholars Program (VSP) is a scientific partnership program that offers extramural scientists access to the intellectual capital and state-of-the-art facilities of the Frederick National Laboratory for Cancer Research (FNLCR), the only na

Development of Medical Technology for Contingency Response to Marrow Toxic Agents

DTIC Science & Technology

2013-04-29

Period 1 5a. CONTRACT NUMBER N/A 5b. GRANT NUMBER N00014-13-1-0039 5c. PROGRAM ELEMENT NUMBER N/A 6. AUTHOR( S ) Spellman, Stephen 5d. PROJECT...NUMBER N/A 5e. TASK NUMBER Project 1, 2, 3, 4 5f. WORK UNIT NUMBER N/A 7. PERFORMING ORGANIZATION NAME( S ) AND ADDRESS(ES) National Marrow Donor... S ) AND ADDRESS(ES) Office of Naval Research 875 N. Randolph St. Arlington, VA 22203 10. SPONSOR/MONITOR’S ACRONYM( S ) ONR 11. SPONSORING/MONITORING

The U.S. Navy Littoral Combat Ship: Current Issues and How to Employ It in the Future

DTIC Science & Technology

2012-03-07

Ship: NIA Curr-ent Issues and How to Deploy It in the Future 5b. GRANT NUMBER N/A 5c. PROGRAM ELEMENT NUMBER N/A 6. AUTHORCSl 5d. PROJECT NUMBER...Lieutenant Commander Gregory M Zimmerman, United States Navy N/A 5e. TASK NUMBER N/A 5f. WORK UNIT NUMBER NIA 7. PERFORMING ORGANIZATION NAME(S...Launch Module, MH-60R helicopter, UAV (Fire Scout), Mission Package Application Software Module, and the optional Maritime Security Module. 27 LCS can

NPF MECHANICAL CELL NaK DISPOSAL AND FUME ABATEMENT

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rey, G.

Some of the fuels originally scheduled for processing in the nonproduction fuel (NPF) processing program incorporated sodium or sodium- potassium alloy (NaK) as the bonding material between stainless-steel cladding and the uranium or uranium-molybdenum alloy core. Because of the special hazards involved in handling NaK, studies were made to determine safe methods for processing NaK-containing fuels. An underwater NaK dispensing system was installed, and tests were made to determine the characteristics of the NaK-water reaction. The equipment consisted of a dispenser, reaction pan, and off-gas scrubber. After initinl studies, a prototype test was made wherein U-Mo canned slugs containing NaKmore » reservoirs were hack sawed underwater. The studies demonstrated that the NaK reservoirs can be safely deactivated by hack sawing under a submerged hood in a shallow water bath. (W.L.H.)« less

The Moon in the Russian scientific-educational project: Kazan-GeoNa-2010

NASA Astrophysics Data System (ADS)

Gusev, A.; Kitiashvili, I.; Petrova, N.

Historically thousand-year Kazan city and the two-hundred-year Kazan university Russia carry out a role of the scientific-organizational and cultural-educational center of Volga region For the further successful development of educational and scientific-educational activity of the Russian Federation the Republic Tatarstan Kazan is offered the national project - the International Center of the Science and the Internet of Technologies bf GeoNa bf Geo metry of bf Na ture - bf GeoNa is developed - wisdom enthusiasm pride grandeur which includes a modern complex of conference halls up to 4 thousand places the Center the Internet of Technologies 3D Planetarium - development of the Moon PhysicsLand an active museum of natural sciences an oceanarium training a complex Spheres of Knowledge botanical and landscape oases In center bf GeoNa will be hosted conferences congresses fundamental scientific researches of the Moon scientific-educational actions presentation of the international scientific programs on lunar research modern lunar databases exhibition Hi-tech of the equipment the extensive cultural-educational tourist and cognitive programs Center bf GeoNa will enable scientists and teachers of the Russian universities to join to advanced achievements of a science information technologies to establish scientific communications with foreign colleagues in sphere of the high technology and educational projects with world space centers

AIM-120 Advanced Medium Range Air-to-Air Missile (AMRAAM)

DTIC Science & Technology

2013-12-01

lilA (DAB) DAE Program Review Start Production Deliveries Complete DAOT&E (Air Force) Complete IOT &E!Captive Ca ... Initial EQuipage Milestone... IOT &E OCT 1983 N/A N/A OCT 1983 Certification FEB 1986 FEB 1986 AUG 1986 FEB 1986 Milestone IIIA (DAB) JUN 1987 JUN 1987 DEC 1987 JUN 1987 DAE...Program Review MAY 1988 MAY 1988 NOV 1988 MAY 1988 Start Production Deliveries SEP 1988 SEP 1988 MAR 1989 SEP 1988 Complete D/ IOT &E (Air Force) JAN 1989 JAN

Quarterly Performance/Technical Report of the National Marrow Donor Program

DTIC Science & Technology

2009-02-10

and epitope level matching for HLA-DPB1. Submitted. o Z Shamim , L Ryder, M Haagenson , S Spellman, T Wang, S Lee, K Müller. Polymorphism in the...3, 4 6. AUTHOR( S ) Setterholm, Michelle 5f. WORK UNIT NUMBER N/A 7. PERFORMING ORGANIZATION NAME( S ) AND ADDRESS(ES) National Marrow Donor...Program 3001 Broadway St., N.E., Ste. 500 Minneapolis, MN 55413 8. PERFORMING ORGANIZATION REPORT NUMBER N/A 10. SPONSOR/MONITOR’S ACRONYM( S ) ONR 9

NaK loop testing of thermoelectric converter modules (SNAP program)

NASA Technical Reports Server (NTRS)

Johnson, J. L.

1973-01-01

The history of testing of compact tubular modules in flowing NaK loops is summarized. Test procedures, data handling, and instrument calibration are discussed. Also included is descriptive information of the test facilities, operational problems encountered, and some recommendations for testing.

Prenatal programming of adult mineral metabolism: relevance to blood pressure, dietary prevention strategies, and cardiovascular disease.

PubMed

Schulter, Günter; Goessler, Walter; Papousek, Ilona

2012-01-01

Mounting evidence indicates that adult health outcomes such as the development of cardiovascular disease or diabetes can trace some of their roots back to prenatal development. This study investigated the epigenetic impact of a particular prenatal hormonal condition on specific health-related consequences, i.e., on concentrations of minerals and mineral metabolism in adults. In 70 university students, the second-to-fourth digit length (2D:4D) was measured as a proxy of prenatal sex steroid action, and the concentrations of sodium (Na), potassium (K), magnesium (Mg), and calcium (Ca) were determined in hair samples by inductively coupled plasma-mass spectrometry. Mineral concentrations and the mineral ratios Na/K, Na/Mg, and Na/Ca were analyzed in multivariate analyses of variance, with digit ratios and sex of participants as grouping variables. The results were validated in a replication cohort from the general population, and with a wider age-range. In addition, the correlation of mineral concentrations and mineral ratios with blood pressure was examined. Men with relatively lower (i.e., more masculine) and women with relatively higher (i.e., more feminine) digit ratios had higher Na/K, Na/Mg, and Na/Ca ratios than their counterparts. Virtually identical results were obtained in the replication study. Moreover, Na concentrations and Na/K ratios were significantly correlated with systolic blood pressure. The findings suggest that the individual variation in mineral metabolism can be predicted by 2D:4D, indicating that prenatal sex steroid action may be involved in the epigenetic programming of specific metabolic conditions which are highly relevant to adult health and disease. 2011 Wiley Periodicals, Inc.

[Prevalence of vitamin a deficiency and anemia in children under five years of age in Peru].

PubMed

Pajuelo, Jaime; Miranda, Marianella; Zamora, Rosa

2015-01-01

To determine the prevalence of vitamin A deficiency (VAD) and nutritional anemia (NA) in children under five in Peru. Cross-sectional study with a stratified and multi-staged probabilistic sample conducted between November 2007 and April 2010.2,736 children were included for NA and 1,465 children for VAD. NA was defined as Hb<11 g/dL.VAD was identified by serum retinol levels <20 µg/dL. Sociodemographic variables related to the child and the mother were studied in addition to their participation in growth control and development programs, integrated nutrition program and supplementation with iron and vitamin A. Analysis of complex samples was performed, descriptive statistics and logistic regression with 95% confidence intervals and a significance level of p<0.05 were calculated. The prevalence of VAD was 11.7% (95% CI: 9.4 to 14.4). The highest prevalences were in children under five months (44.6%) and those living in rural areas (19.5%). The prevalence of NA was 33% (95% CI: 29.9 to 36.1) and was higher in children under 11 months (68.2%) and children of mothers aged 13-19 years old (55.4 %). VAD is a public health problem that remains, with the most affected children living in rural areas and in the jungle. The prevalence of NA shows a slight improvement. It is necessary to improve the efficiency and impact of programs that include supplementation of vitamin A and iron.

Advances in neglected tropical disease vaccines: Developing relative potency and functional assays for the Na-GST-1/Alhydrogel hookworm vaccine.

PubMed

Brelsford, Jill B; Plieskatt, Jordan L; Yakovleva, Anna; Jariwala, Amar; Keegan, Brian P; Peng, Jin; Xia, Pengjun; Li, Guangzhao; Campbell, Doreen; Periago, Maria Victoria; Correa-Oliveira, Rodrigo; Bottazzi, Maria Elena; Hotez, Peter J; Diemert, David; Bethony, Jeffrey M

2017-02-01

A new generation of vaccines for the neglected tropical diseases (NTDs) have now advanced into clinical development, with the Na-GST-1/Alhydrogel Hookworm Vaccine already being tested in Phase 1 studies in healthy adults. The current manuscript focuses on the often overlooked critical aspects of NTD vaccine product development, more specifically, vaccine stability testing programs. A key measure of vaccine stability testing is "relative potency" or the immunogenicity of the vaccine during storage. As with most NTD vaccines, the Na-GST-1/Alhydrogel Hookworm Vaccine was not developed by attenuation or inactivation of the pathogen (Necator americanus), so conventional methods for measuring relative potency are not relevant for this investigational product. Herein, we describe a novel relative potency testing program and report for the first time on the clinical lot of this NTD vaccine during its first 60 months of storage at 2-8°C. We also describe the development of a complementary functional assay that measures the ability of IgG from animals or humans immunized with Na-GST-1/Alhydrogel to neutralize this important hookworm enzyme. While 90% inhibition of the catalytic activity of Na-GST-1 was achieved in animals immunized with Na-GST-1/Alhydrogel, lower levels of inhibition were observed in immunized humans. Moreover, anti-Na-GST-1 antibodies from volunteers in non-hookworm endemic areas were better able to inhibit catalytic activity than anti-Na-GST-1 antibodies from volunteers resident in hookworm endemic areas. The results described herein provide the critical tools for the product development of NTD vaccines.

Modeling Laboratory Astrophysics Experiments using the CRASH code

NASA Astrophysics Data System (ADS)

Trantham, Matthew; Drake, R. P.; Grosskopf, Michael; Bauerle, Matthew; Kruanz, Carolyn; Keiter, Paul; Malamud, Guy; Crash Team

2013-10-01

The understanding of high energy density systems can be advanced by laboratory astrophysics experiments. Computer simulations can assist in the design and analysis of these experiments. The Center for Radiative Shock Hydrodynamics (CRASH) at the University of Michigan developed a code that has been used to design and analyze high-energy-density experiments on OMEGA, NIF, and other large laser facilities. This Eulerian code uses block-adaptive mesh refinement (AMR) with implicit multigroup radiation transport and electron heat conduction. This poster/talk will demonstrate some of the experiments the CRASH code has helped design or analyze including: Radiative shocks experiments, Kelvin-Helmholtz experiments, Rayleigh-Taylor experiments, plasma sheet, and interacting jets experiments. This work is funded by the Predictive Sciences Academic Alliances Program in NNSA-ASC via grant DEFC52- 08NA28616, by the NNSA-DS and SC-OFES Joint Program in High-Energy-Density Laboratory Plasmas, grant number DE-FG52-09NA29548, and by the National Laser User Facility Program, grant number DE-NA0000850.

Deciphering early events involved in hyperosmotic stress-induced programmed cell death in tobacco BY-2 cells.

PubMed

Monetti, Emanuela; Kadono, Takashi; Tran, Daniel; Azzarello, Elisa; Arbelet-Bonnin, Delphine; Biligui, Bernadette; Briand, Joël; Kawano, Tomonori; Mancuso, Stefano; Bouteau, François

2014-03-01

Hyperosmotic stresses represent one of the major constraints that adversely affect plants growth, development, and productivity. In this study, the focus was on early responses to hyperosmotic stress- (NaCl and sorbitol) induced reactive oxygen species (ROS) generation, cytosolic Ca(2+) concentration ([Ca(2+)]cyt) increase, ion fluxes, and mitochondrial potential variations, and on their links in pathways leading to programmed cell death (PCD). By using BY-2 tobacco cells, it was shown that both NaCl- and sorbitol-induced PCD seemed to be dependent on superoxide anion (O2·(-)) generation by NADPH-oxidase. In the case of NaCl, an early influx of sodium through non-selective cation channels participates in the development of PCD through mitochondrial dysfunction and NADPH-oxidase-dependent O2·(-) generation. This supports the hypothesis of different pathways in NaCl- and sorbitol-induced cell death. Surprisingly, other shared early responses, such as [Ca(2+)]cyt increase and singlet oxygen production, do not seem to be involved in PCD.

Comprehensive Clinical Phenotyping and Genetic Mapping for the Discovery of Autism Susceptibility Genes

DTIC Science & Technology

2013-03-14

SUPPLEMENTARY NOTES 14. ABSTRACT Autism is an extremely common and heterogeneous neurodevelopmental disorder. While genetic factors are known to play...AFRL-SA-WP-TR-2013-0013 Comprehensive Clinical Phenotyping and Genetic Mapping for the Discovery of Autism Susceptibility Genes...Genetic Mapping for the Discovery of Autism Susceptibility Genes 5a. CONTRACT NUMBER N/A 5b. GRANT NUMBER N/A 5c. PROGRAM ELEMENT NUMBER N/A 6

03pd0676

NASA Image and Video Library

2003-03-07

File name :DSC_0749.JPG File size :1.1MB(1174690Bytes) Date taken :2003/03/07 13:51:29 Image size :2000 x 1312 Resolution :300 x 300 dpi Number of bits :8bit/channel Protection attribute :Off Hide Attribute :Off Camera ID :N/A Camera :NIKON D1H Quality mode :FINE Metering mode :Matrix Exposure mode :Shutter priority Speed light :No Focal length :20 mm Shutter speed :1/500second Aperture :F11.0 Exposure compensation :0 EV White Balance :Auto Lens :20 mm F 2.8 Flash sync mode :N/A Exposure difference :0.0 EV Flexible program :No Sensitivity :ISO200 Sharpening :Normal Image Type :Color Color Mode :Mode II(Adobe RGB) Hue adjustment :3 Saturation Control :N/A Tone compensation :Normal Latitude(GPS) :N/A Longitude(GPS) :N/A Altitude(GPS) :N/A

Sodium-promoted Pd/TiO2 for catalytic oxidation of formaldehyde at ambient temperature.

PubMed

Zhang, Changbin; Li, Yaobin; Wang, Yafei; He, Hong

2014-05-20

Catalytic oxidation of formaldehyde (HCHO) to CO2 at ambient conditions is of great interest for indoor HCHO purification. Here, we report that sodium-doped Pd/TiO2 is a highly effective catalyst for the catalytic oxidation of HCHO at room temperature. It was observed that Na doping has a dramatic promotion effect on the Pd/TiO2 catalyst and that nearly 100% HCHO conversion could be achieved over the 2Na-Pd/TiO2 catalyst at a GHSV of 95000 h(-1) and HCHO inlet concentration of 140 ppm at 25 °C. The mechanism of the Na-promotion effect was investigated by using Brunauer-Emmett-Teller (BET), X-ray diffraction (XRD), CO chemisorption, Temperature-programmed reduction by H2 (H2-TPR), X-ray photoelectron spectroscopy (XPS) and temperature-programmed desorption of O2 (O2-TPD) methods. The results showed that Na species addition can induce and further stabilize a negatively charged and well-dispersed Pd species, which then facilitates the activation of H2O and chemisorbed oxygen, therefore resulting in the high performance of the 2Na-Pd/TiO2 catalyst for the ambient HCHO destruction.

Thermochemical Properties of the Lattice Oxygen in W,Mn-Containing Mixed Oxide Catalysts for the Oxidative Coupling of Methane

NASA Astrophysics Data System (ADS)

Lomonosov, V. I.; Gordienko, Yu. A.; Sinev, M. Yu.; Rogov, V. A.; Sadykov, V. A.

2018-03-01

Mixed NaWMn/SiO2 oxide, samples containing individual components (Na, W, Mn) and their double combinations (Na-W, Na-Mn, W-Mn) supported on silica were studied by temperature programmed reduction (TPR) and desorption (TPD), and heat flow calorimetry during their reoxidation with molecular oxygen in pulse mode. The NaWMn/SiO2 mixed oxide was shown to contain two different types of reactive lattice oxygen. The weakly-bonded oxygen can be reversibly released from the oxide in a flow of inert gas in the temperature range of 575‒900°C, while the strongly-bonded oxygen can be removed during the reduction of the sample with hydrogen at 700-900°C. The measured thermal effect of oxygen consumption for these two oxygen forms are 185 and 350 kJ/mol, respectively. The amount of oxygen removed at reduction ( 443 μmol/g) considerably exceeded the amount desorbed in an inert gas flow ( 56 μmol/g). The obtained results suggest that the reversible oxygen desorption is due to the redox process in which manganese ions are involved, while during the temperature programmed reduction, mainly oxygen bonded with tungsten is removed.

Recent results from the strong interactions program of NA61/SHINE

NASA Astrophysics Data System (ADS)

Pulawski, Szymon

2017-12-01

The NA61/SHINE experiment studies hadron production in hadron+hadron, hadron+nucleus and nucleus+nucleus collisions. The strong interactions program has two main purposes: study the properties of the onset of deconfinement and search for the signatures of the critical point of strongly interacting matter. This aim is pursued by performing a two-dimensional scan of the phase diagram by varying the energy/momentum (13A-158A GeV/c) and the system size (p+p, Be+Be, Ar+Sc, Xe+La) of the collisions. This publication reviews recent results from p+p, Be+Be and Ar+Sc interactions. Measured particle spectra are discussed and compared to NA49 results from Pb+Pb collisions. The results illustrate the progress towards scanning the phase diagram of strongly interacting matter.

Advanced Nondestructive Evaluation (NDE) for Retirement for Cause/Engine Structural Integrity Program (RFC/RNSIP)

DTIC Science & Technology

2000-08-01

7.5mVpp @ 20KHz 6Vpp @ 6MHz Input N/A N/A 206mVpp @ 6MHz 157mVpp @ 6MHz 66mVpp @ 6MHz 99mVpp @ 6MHz 91mVpp @ 6MHz No Input 35mVpp @ 113KHz 3mVpp...170MHz 8.5mVpp @ 200MHz 13mVpp @ 200MHz 22mVpp @ 113KHz 5mVpp @ 113KHz 4.5mVpp @ 113KHz 6Vpp @ 6MHz Input N/A N/A 300mVpp @ 6MHz 285mVpp

Assessment of soil and wash water quality beneath salt-spreader racks.

DOT National Transportation Integrated Search

2008-01-01

The Virginia Department of Transportation's (VDOT) winter maintenance program hinges primarily on the use of granular NaCl for deicing. On average, VDOT applies more than 300,000 tons of NaCl each winter season. The majority of this salt is spread by...

Sodium-NaK engineering handbook. Volume III. Sodium systems, safety, handling, and instrumentation. [LMFBR

DOE Office of Scientific and Technical Information (OSTI.GOV)

Foust, O J

1978-01-01

The handbook is intended for use by present and future designers in the Liquid Metals Fast Breeder Reactor (LMFBR) Program and by the engineering and scientific community performing other type investigation and exprimentation requiring high-temperature sodium and NaK technology. The arrangement of subject matter progresses from a technological discussion of sodium and sodium--potassium alloy (NaK) to discussions of varius categories and uses of hardware in sodium and NaK systems. Emphasis is placed on sodium and NaK as heat-transport media. Sufficient detail is included for basic understanding of sodium and NaK technology and of technical aspects of sodium and NaK componentsmore » and instrument systems. Information presented is considered adequate for use in feasibility studies and conceptual design, sizing components and systems, developing preliminary component and system descriptions, identifying technological limitations and problem areas, and defining basic constraints and parameters.« less

76 FR 8659 - Structure and Practices of the Video Relay Service Program

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-15

... Practices of the Video Relay Service Program AGENCY: Federal Communications Commission. ACTION: Final rule... with the Commission's Structure and Practices of the Video Relay Service Program, Declaratory Ruling... Practices of the Video Relay Service Program, CG Docket No. 10-51. Form Number: N/A. Respondents: Business...

Advances in neglected tropical disease vaccines: Developing relative potency and functional assays for the Na-GST-1/Alhydrogel hookworm vaccine

PubMed Central

Brelsford, Jill B.; Plieskatt, Jordan L.; Yakovleva, Anna; Jariwala, Amar; Keegan, Brian P.; Peng, Jin; Xia, Pengjun; Li, Guangzhao; Campbell, Doreen; Periago, Maria Victoria; Correa-Oliveira, Rodrigo; Bottazzi, Maria Elena; Hotez, Peter J.

2017-01-01

A new generation of vaccines for the neglected tropical diseases (NTDs) have now advanced into clinical development, with the Na-GST-1/Alhydrogel Hookworm Vaccine already being tested in Phase 1 studies in healthy adults. The current manuscript focuses on the often overlooked critical aspects of NTD vaccine product development, more specifically, vaccine stability testing programs. A key measure of vaccine stability testing is "relative potency" or the immunogenicity of the vaccine during storage. As with most NTD vaccines, the Na-GST-1/Alhydrogel Hookworm Vaccine was not developed by attenuation or inactivation of the pathogen (Necator americanus), so conventional methods for measuring relative potency are not relevant for this investigational product. Herein, we describe a novel relative potency testing program and report for the first time on the clinical lot of this NTD vaccine during its first 60 months of storage at 2–8°C. We also describe the development of a complementary functional assay that measures the ability of IgG from animals or humans immunized with Na-GST-1/Alhydrogel to neutralize this important hookworm enzyme. While 90% inhibition of the catalytic activity of Na-GST-1 was achieved in animals immunized with Na-GST-1/Alhydrogel, lower levels of inhibition were observed in immunized humans. Moreover, anti-Na-GST-1 antibodies from volunteers in non-hookworm endemic areas were better able to inhibit catalytic activity than anti-Na-GST-1 antibodies from volunteers resident in hookworm endemic areas. The results described herein provide the critical tools for the product development of NTD vaccines. PMID:28192438

78 FR 45213 - Medicaid Program; State Allotments for Payment of Medicare Part B Premiums for Qualifying...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-26

...,957,698 4,295,522 NA NA 3,662,176......... 2.2728 2,353,604......... NA 5,604,094 Delaware 4 0.28 2... 0.0867 Need Need Need 89,747 18,127,195 Louisiana 29 2.01 15,384,882 22,144,578 6,759,696......... 6.5277 Need Need Need 6,759,696......... 22,144,578 Maine 7 0.49 3,713,592 7,045,460 3,331,867......... 3...

Generating Lookup Tables from the AE9/AP9 Models

DTIC Science & Technology

2015-06-16

AP9 Models 5a. CONTRACT NUMBER FA8802-14-C-0001 5b. GRANT NUMBER na 5c. PROGRAM ELEMENT NUMBER 5811 6. AUTHOR( S ) Joshua P. Davis 5d. PROJECT...NUMBER 11 5e. TASK NUMBER na 5f. WORK UNIT NUMBER na 7. PERFORMING ORGANIZATION NAME( S ) AND ADDRESS(ES) The Aerospace Corporation 2310 E. El...Segundo Blvd. El Segundo, CA 90245-4609 8. PERFORMING ORGANIZATION REPORT NUMBER TOR-2015-00893 9. SPONSORING/MONITORING AGENCY NAME( S ) AND ADDRESS

JCL (Job Control Language) Procedures to Run the Hull Code on the Cyber 205 Computer Installed on CSIRONET.

DTIC Science & Technology

1986-11-01

START THE RUN>>> USERNUIDNUPW. CHARGEGROUPNPID. SETJOB, DC= NO . COMMENT . GET CR ATTACH THE INPUT DATA TO GO TO VSOS. GET, INDATA=DATFILE/NA. IFE...NtPW. CHARGEGROUPNPID. SETTL, 200. SETJOB. DC= NO . COMMENT . RUN SAIL ON NOS TO GENERATE THE MAIN PROGRAM. PURGE, SAl LOUT/NA. PURGE, PROG-PROBLEMID...NOSPASS. CHARGEDFCDFCPR.F. SETJOB. DC= NO . COMMENT . GET OR ATTACH THE INPUT DATA To Go To VSOS. GET. INDATA=MYDATA/NA. IFE. .NOT.FILE(INDATA.AS) .DOATT

Electromagnetic Aircraft Launching System: Do the Benefits Outweigh the Costs?

DTIC Science & Technology

2010-03-29

Launching System: N/A Do the Benefits Outweigh the Costs? 5b. GRANT NUMBER N/A 5c. PROGRAM ELEMENT NUMBER ’ N/A 6. AUTHOR(S) 5d. PROJECT NUMBER Hartman...levitation (MAGLEV) trains. State-of-the-art systems make up the components of the system. There are several benefits the EIV1ALS has over the current...Do the Benefits Outweigh the Costs? SUBMITTED IN PARTIAL I:tJLFILLMENT OF THE REQUIREMENTS FOR THE DEGREE OF MASTER OF MILITARY STUDIES Author

The Need For and Benefits of the Creation of the Light Armored Reconnaissance Regiment

DTIC Science & Technology

2010-04-14

instead of the 8 battalions reporting straight to a commanding general provides significant advantages . When asked about the benefits of the recent...The Need For and Benefits of the Creation of the Light Armored N/A Reconnaissance Regiment 5b. GRANT NUMBER N/A 5c. PROGRAM ELEMENT NUMBER N/A 6...MASTER OF MILITARY STUDIES THE NEED FOR AND BENEFITS OF THECREATION OF THE LIGHT ARMORED RECONNAISSANCE REGIMENT SUBMITTED IN PARTIAL FULFILLMENT OF

A Study to Develop an Assessment Tool and Evaluate the Social Work Service Quality Assurance Plan at Walter Reed Army Medical Center, Brooke Army Medical Center, and Fitzsimons Army Medical Center

DTIC Science & Technology

1987-07-01

the plan identify methods of integration with other military services (Army Community Service, Ariny Drug and Alcohol Prevention and Control Program...home care or out-of-home care setting. 1 2 3 4 5 NA 21.2.2.4 Patient safety and infection control . 1 2 3 4 5 NA 21.2.3 Personnel who provide social...4 5 NA SO2.2.4 Patient safety and infection control . 1 2 3 4 5 NA SO.2.3 Personnel who provide social work services participate in relevant continuing

77 FR 27837 - Pilot Program on NAFTA Trucking Provisions

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-11

... Federal de Conductor and English language proficiency. L. If No, Which Element Failed: If FMCSA cannot... collection facility 1 Higienicos y 710491 MX-327700 N/A Pass 1 1 US RMC Testing Desechables del Solutions. Bajio SA de CV. 2 Servicios 1052546 MX-440938 N/A Pass 1 1 US RMC Testing Refrigerados Solutions...

Space nuclear system thermoelectric NaK pump development

NASA Technical Reports Server (NTRS)

Johnson, J. L.

1973-01-01

The engineering, design, fabrication, and test history of the dual-throat thermoelectric NaK development pump is summarized, along with the engineering and design status of a similar prototype pump intended for use on the 5-kwe reactor thermoelectric system. The history of dc pump development and testing on previous programs is also summarized.

Generating Long Scale-Length Plasma Jets Embedded in a Uniform, Multi-Tesla Magnetic-Field

NASA Astrophysics Data System (ADS)

Manuel, Mario; Kuranz, Carolyn; Rasmus, Alex; Klein, Sallee; Fein, Jeff; Belancourt, Patrick; Drake, R. P.; Pollock, Brad; Hazi, Andrew; Park, Jaebum; Williams, Jackson; Chen, Hui

2013-10-01

Collimated plasma jets emerge in many classes of astrophysical objects and are of great interest to explore in the laboratory. In many cases, these astrophysical jets exist within a background magnetic field where the magnetic pressure approaches the plasma pressure. Recent experiments performed at the Jupiter Laser Facility utilized a custom-designed solenoid to generate the multi-tesla fields necessary to achieve proper magnetization of the plasma. Time-gated interferometry, Schlieren imaging, and proton radiography were used to characterize jet evolution and collimation under varying degrees of magnetization. Experimental results will be presented and discussed. This work is funded by the NNSA-DS and SC-OFES Joint Program in High-Energy-Density Laboratory Plasmas, grant number DE-NA0001840, by the National Laser User Facility Program, grant number DE-NA0000850, by the Predictive Sciences Academic Alliances Program in NNSA-ASC, grant number DEFC52-08NA28616, and by NASA through Einstein Postdoctoral Fellowship grant number PF3-140111 awarded by the Chandra X-ray Center, which is operated by the Smithsonian Astrophysical Observatory for NASA under contract NAS8-03060.

Deciphering early events involved in hyperosmotic stress-induced programmed cell death in tobacco BY-2 cells

PubMed Central

Monetti, Emanuela; Kadono, Takashi; Bouteau, François

2014-01-01

Hyperosmotic stresses represent one of the major constraints that adversely affect plants growth, development, and productivity. In this study, the focus was on early responses to hyperosmotic stress- (NaCl and sorbitol) induced reactive oxygen species (ROS) generation, cytosolic Ca2+ concentration ([Ca2+]cyt) increase, ion fluxes, and mitochondrial potential variations, and on their links in pathways leading to programmed cell death (PCD). By using BY-2 tobacco cells, it was shown that both NaCl- and sorbitol-induced PCD seemed to be dependent on superoxide anion (O2·–) generation by NADPH-oxidase. In the case of NaCl, an early influx of sodium through non-selective cation channels participates in the development of PCD through mitochondrial dysfunction and NADPH-oxidase-dependent O2·– generation. This supports the hypothesis of different pathways in NaCl- and sorbitol-induced cell death. Surprisingly, other shared early responses, such as [Ca2+]cyt increase and singlet oxygen production, do not seem to be involved in PCD. PMID:24420571

NaJAZh Regulates a Subset of Defense Responses against Herbivores and Spontaneous Leaf Necrosis in Nicotiana attenuata Plants[C][W][OA

PubMed Central

Oh, Youngjoo; Baldwin, Ian T.; Gális, Ivan

2012-01-01

The JASMONATE ZIM DOMAIN (JAZ) proteins function as negative regulators of jasmonic acid signaling in plants. We cloned 12 JAZ genes from native tobacco (Nicotiana attenuata), including nine novel JAZs in tobacco, and examined their expression in plants that had leaves elicited by wounding or simulated herbivory. Most JAZ genes showed strong expression in the elicited leaves, but NaJAZg was mainly expressed in roots. Another novel herbivory-elicited gene, NaJAZh, was analyzed in detail. RNA interference suppression of this gene in inverted-repeat (ir)JAZh plants deregulated a specific branch of jasmonic acid-dependent direct and indirect defenses: irJAZh plants showed greater trypsin protease inhibitor activity, 17-hydroxygeranyllinalool diterpene glycosides accumulation, and emission of volatile organic compounds from leaves. Silencing of NaJAZh also revealed a novel cross talk in JAZ-regulated secondary metabolism, as irJAZh plants had significantly reduced nicotine levels. In addition, irJAZh spontaneously developed leaf necrosis during the transition to flowering. Because the lesions closely correlated with the elevated expression of programmed cell death genes and the accumulations of salicylic acid and hydrogen peroxide in the leaves, we propose a novel role of the NaJAZh protein as a repressor of necrosis and/or programmed cell death during plant development. PMID:22496510

TU-G-BRD-06: The Imaging and Radiation Oncology Core Houston (IROC Houston) QA Center International Activities Outside North America

DOE Office of Scientific and Technical Information (OSTI.GOV)

Followill, D; Kry, S; Molineu, A

Purpose: To describe the extent of IROC Houston’s (formerly the RPC) QA activities and audit results for radiotherapy institutions outside of North America (NA). Methods: The IROC Houston’s QA program components were designed to audit the radiation dose calculation chain from the NIST traceable reference beam calibration, to inclusion of dosimetry parameters used to calculate tumor doses, to the delivery of the radiation dose. The QA program provided to international institutions includes: 1) remote TLD/OSLD audit of machine output, 2) credentialing for advanced technologies, and 3) review of patient treatment records. IROC Houston uses the same standards and acceptance criteriamore » for all of its audits whether for North American or international sites. Results: IROC Houston’s QA program has reached out to radiotherapy sites in 43 different countries since 2013 through their participation in clinical trials. In the past two years, 2,778 international megavoltage beam outputs were audited with OSLD/TLD. While the average IROC/Inst ratio is near unity for all sites monitored, there are international regions whose results are significantly different from the NA region. In the past 2 years, 477 and 87 IMRT H&N phantoms were irradiated at NA and international sites, respectively. Regardless of the OSLD beam audit results, the overall pass rate (87 percent) for all international sites (no region separation) is equal to the NA sites. Of the 182 international patient charts reviewed, 10.7 percent of the dose calculation points did not meet our acceptance criterion as compared to 13.6 percent for NA sites. The lower pass rate for NA sites results from a much larger brachytherapy component which has been shown to be more error prone. Conclusion: IROC Houston has expanded its QA services worldwide and continues a long history of improving radiotherapy dose delivery in many countries. Funding received for QA audit services from the Korean GOG, DAHANCA, EORTC, ICON and CMIC Group.« less

INTEX-NA: Intercontinental Chemical Transport Experiment - North America

NASA Technical Reports Server (NTRS)

Singh, Hanwant B.; Jacob, D.; Pfister, L.; Hipskind, R. Stephen (Technical Monitor)

2002-01-01

INTEX-NA is an integrated atmospheric chemistry field experiment to be performed over North America using the NASA DC-8 and P-3B aircraft as its primary platforms. It seeks to understand the exchange of chemicals and aerosols between continents and the global troposphere. The constituents of interest are ozone and its precursors (hydrocarbons, NOX and HOX), aerosols, and the major greenhouse gases (CO2, CH4, N2O). INTEX-NA will provide the observational database needed to quantify inflow, outflow, and transformations of chemicals over North America. INTEX-NA is to be performed in two phases. Phase A will take place during the period of May-August 2004 and Phase B during March-June 2006. Phase A is in summer when photochemistry is most intense and climatic issues involving aerosols and carbon cycle are most pressing, and Phase B is in spring when Asian transport to North America is at its peak. INTEX-NA will coordinate its activities with concurrent measurement programs including satellites (e. g. Terra, Aura, Envisat), field activities undertaken by the North American Carbon Program (NACP), and other U.S. and international partners. However, it is being designed as a 'stand alone' mission such that its successful execution is not contingent on other programs. Synthesis of the ensemble of observation from surface, airborne, and space platforms, with the help of global/regional models is an important It is anticipated that approximately 175 flight hours for each of the aircraft (DC-8 and P-3B) will be required for each Phase. Principal operational sites are tentatively selected to be Bangor, ME; Wallops Island, VA; Seattle, WA; Rhinelander, WI; Lancaster, CA; and New Orleans, LA. These coastal and continental sites can support large missions and are suitable for INTEX-NA objectives. The experiment will be supported by forecasts from meteorological and chemical models, satellite observations, surface networks, and enhanced O3,-sonde releases. In addition to characterizing Atlantic-outflow and Pacific-inflow, INTEX-NA will characterize air masses transported between the U.S., Canada, and Mexico. INTEX-NA will be the first continental scale inflow, outflow, and transformation experiment to be performed over North America. It will provide the most comprehensive observational data set to date to understand the O3/NOX/HOX/aerosol photochemical system and the carbon cycle. One of the critical needs of the carbon cycle research is to obtain large-scale vertical and horizontal concentration gradients of CO2, throughout the troposphere over continental source/sink regions. INTEX-NA is ideally suited to perform this role. Coastal and continental operational sites will allow us to develop a curtain profile of greenhouse gases (e. g. CO2,) and other key pollutants across North America. Such information is central to our quantitative understanding of chemical budgets on the continental scale. We expect to provide a number of satellite under-flights over land and water to test and validate observations from the appropriate satellite platform (e. g. Aura). We plan to develop strong collaborations with other national and international observational programs. Results from INTEX-NA should directly benefit the development of environmental policy for air quality and climate change.

Europlanet NA2 Science Networking

NASA Astrophysics Data System (ADS)

Harri, Ari-Matti; Szego, Karoly; Genzer, Maria; Schmidt, Walter; Krupp, Norbert; Lammer, Helmut; Kallio, Esa; Haukka, Harri

2013-04-01

Europlanet RI / NA2 Science Networking [1] focused on determining the major goals of current and future European planetary science, relating them to the Research Infrastructure that the Europlanet RI project [2] developed, and placing them in a more global context. NA2 also enhanced the ability of European planetary scientists to participate on the global scene with their own agenda-setting projects and ideas. The Networking Activity NA2 included five working groups, aimed at identifying key science issues and producing reference books on major science themes that will bridge the gap between the results of present and past missions and the scientific preparation of the future ones. Within the Europlanet RI project (2009-2012) the NA2 and NA2-WGs organized thematic workshops, an expert exchange program and training groups to improve the scientific impact of this Infrastructure. The principal tasks addressed by NA2 were: • Science activities in support to the optimal use of data from past and present space missions, involving the broad planetary science community beyond the "space club" • Science activities in support to the preparation of future planetary missions: Earth-based preparatory observations, laboratory studies, R&D on advanced instrumentation and exploration technologies for the future, theory and modeling etc. • Develop scientific activities, joint publications, dedicated meetings, tools and services, education activities, engaging the public and industries • Update science themes and addressing the two main scientific objectives • Prepare and support workshops of the International Space Science Institute (ISSI) in Bern and • Support Trans National Activities (TNAs), Joined Research Activities (JRAs) and the Integrated and Distributed Information Service (IDIS) of the Europlanet project These tasks were achieved by WG workshops organized by the NA2 working groups, by ISSI workshops and by an Expert Exchange Program. There were 17 official WG workshops and in addition there were numerous smaller NA2 WG meetings during the conferences (EPSC, EGU, etc.) and other events. The total number of NA2 meetings and workshops was 37. There were three NA2 supported ISSI workshops within the Europlanet project. The first ISSI workshop "Comparison of the plasma-spheres of Mars, Venus, and Titan" organized by K. Szego was held in December 2009. The second workshop "Quantifying the Martian Geochemical Reservoirs" by M. Toplis was held in April 2011. The third one, themed "Giant Planet Magnetodiscs and Aurorae" by N. Krupp, N. Achilleos and C. Arridge, was in November 2012. All three ISSI workshops were selected by the ISSI scientific committee to be organized within the frame of ISSI/Europlanet agreement and held in Bern. The main objective of the Expert Exchange Program was to support the activities of Europlanet RI with experts whenever needed. The programme provided funding for short visits (up to one week) of expert with the goal of improving infrastructure facilities and services offered to the scientific community by the Europlanet RI participant (contractor) laboratories or institutes. Between July 2009 and September 2012 26 applications were selected. Acknowledgement: Europlanet RI was funded by the European Commission under the 7th Framework Program, grant 228319 "Capacities Specific Programme" - Research Infrastructures Action. References: [1] http://www.europlanet-ri.eu/ [2] https://europlanet-scinet.fi/

Astronomy in the Russian Scientific-Educational Project: "KAZAN-GEONA-2010"

NASA Astrophysics Data System (ADS)

Gusev, A.; Kitiashvili, I.

2006-08-01

The European Union promotes the Sixth Framework Programme. One of the goals of the EU Programme is opening national research and training programs. A special role in the history of the Kazan University was played by the great mathematician Nikolai Lobachevsky - the founder of non-Euclidean geometry (1826). Historically, the thousand-year old city of Kazan and the two-hundred-year old Kazan University carry out the role of the scientific, organizational, and cultural educational center of the Volga region. For the continued successful development of educational and scientific-educational activity of the Russian Federation, the Republic Tatarstan, Kazan was offered the national project: the International Center of the Sciences and Internet Technologies "GeoNa" (Geometry of Nature - GeoNa - is wisdom, enthusiasm, pride, grandeur). This is a modern complex of conference halls including the Center for Internet Technologies, a 3D Planetarium - development of the Moon, PhysicsLand, an active museum of natural sciences, an oceanarium, and a training complex "Spheres of Knowledge". Center GeoNa promotes the direct and effective channel of cooperation with scientific centers around the world. GeoNa will host conferences, congresses, fundamental scientific research sessions of the Moon and planets, and scientific-educational actions: presentation of the international scientific programs on lunar research and modern lunar databases. A more intense program of exchange between scientific centers and organizations for a better knowledge and planning of their astronomical curricula and the introduction of the teaching of astronomy are proposed. Center GeoNa will enable scientists and teachers of the Russian universities with advanced achievements in science and information technologies to join together to establish scientific communications with foreign colleagues in the sphere of the high technology and educational projects with world scientific centers.

Integrated Data Collection Analysis (IDCA) Program - NaClO 3/Icing Sugar

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sandstrom, Mary M.; Brown, Geoffrey W.; Preston, Daniel N.

The Integrated Data Collection Analysis (IDCA) program is conducting a proficiency study for Small- Scale Safety and Thermal (SSST) testing of homemade explosives (HMEs). Described here are the results for impact, friction, electrostatic discharge, and differential scanning calorimetry analysis of a mixture of NaClO 3 and icing sugar—NaClO 3/icing sugar mixture. The mixture was found to: be more sensitive than RDX but less sensitive than PETN in impact testing (180-grit sandpaper); be more sensitive than RDX and about the same sensitivity as PETN in BAM fiction testing; be less sensitive than RDX and PETN except for one participant found themore » mixture more sensitive than PETN in ABL ESD testing; and to have one to three exothermic features with the lowest temperature event occurring at ~ 160°C always observed in thermal testing. Variations in testing parameters also affected the sensitivity.« less

Abscisic acid induction of vacuolar H+-ATPase activity in mesembryanthemum crystallinum is developmentally regulated

PubMed

Barkla; Vera-Estrella; Maldonado-Gama; Pantoja

1999-07-01

Abscisic acid (ABA) has been implicated as a key component in water-deficit-induced responses, including those triggered by drought, NaCl, and low- temperature stress. In this study a role for ABA in mediating the NaCl-stress-induced increases in tonoplast H+-translocating ATPase (V-ATPase) and Na+/H+ antiport activity in Mesembryanthemum crystallinum, leading to vacuolar Na+ sequestration, were investigated. NaCl or ABA treatment of adult M. crystallinum plants induced V-ATPase H+ transport activity, and when applied in combination, an additive effect on V-ATPase stimulation was observed. In contrast, treatment of juvenile plants with ABA did not induce V-ATPase activity, whereas NaCl treatment resulted in a similar response to that observed in adult plants. Na+/H+ antiport activity was induced in both juvenile and adult plants by NaCl, but ABA had no effect at either developmental stage. Results indicate that ABA-induced changes in V-ATPase activity are dependent on the plant reaching its adult phase, whereas NaCl-induced increases in V-ATPase and Na+/H+ antiport activity are independent of plant age. This suggests that ABA-induced V-ATPase activity may be linked to the stress-induced, developmentally programmed switch from C3 metabolism to Crassulacean acid metabolism in adult plants, whereas, vacuolar Na+ sequestration, mediated by the V-ATPase and Na+/H+ antiport, is regulated through ABA-independent pathways.

The USAF Phillips Laboratory sodium-sulfur battery technology program: Results and status

NASA Technical Reports Server (NTRS)

Rainbow, Marc E.; Somerville, Andrew

1996-01-01

Tests performed on NaS batteries are reported. The results of safety and abuse testing, shock and vibration tests, cell failure on warm-up, freeze thaw, overtemperature conditions, electrolyte fracture, overdischarge, and short circuit tests are presented along with GEO and LEO cycle tests and the status of the NaS cell flight tests.

X-Ray Laser Program Final Report for FY91

DTIC Science & Technology

1992-09-16

from a Na z pinch is used to photoionize Ne to the He-like ground state and radiation from the Na 1 s 2-1 s2p 1P1 transition is used to resonantly...creating photopumped x-ray lasers2 , imploding inertial confinement fusion capsules, 3 and studying the photoionization kinetics of plasmas in intense...has received extensive theoretical study, 5 -8 employs radiation from the 1s2 -1s2p 1P1 transition at 11.0027 A in He-like Na to resonantly photoexcite

Automated Program Analysis for Cybersecurity (APAC)

DTIC Science & Technology

2016-07-14

AUTOMATED PROGRAM ANALYSIS FOR CYBERSECURITY (APAC) FIVE DIRECTIONS, INC JULY 2016 FINAL TECHNICAL REPORT APPROVED... CYBERSECURITY (APAC) 5a. CONTRACT NUMBER FA8750-14-C-0050 5b. GRANT NUMBER N/A 5c. PROGRAM ELEMENT NUMBER 61101E 6. AUTHOR(S) William Arbaugh...AC Team Adversarial Challenge Team, responsible for creating malicious applications APAC Automated Program Analysis for Cybersecurity BAE BAE Systems

Effects of silicate weathering on water chemistry in forested, upland, felsic terrane of the USA

NASA Astrophysics Data System (ADS)

Stauffer, Robert E.; Wittchen, Bruce D.

1991-11-01

We use data from the US EPA National Surface Water Survey (NSWS), the USGS Bench-Mark Station monitoring program, and the National Acid Deposition Program (NADP) to evaluate the role of weathering in supplying base cations to surface waters in forested, upland, felsic terrane of the northeastern, northcentral, and northwestern (Idaho batholith) United States. Multivariate regression reveals differential effects of discharge on individual base cations and silica, but no secular trend in the Ca/Na denudation rate over 24 yr (1965-1988) for the Wild River catchment in the White Mountains. Because the turn-over time for Na in the soil-exchange complex is only ca. 1.5 yr, the long-term behavior of the ratios Ca/Na and Si/Na in waters leaving this catchment indicates that weathering is compensating for base cation export. In every subregion, Ca and Mg concentrations in lakes are statistically linked to nonmarine Na, but the median Ca/Na ratio is greater than the ratio in local plagioclase. We attribute this inequality to nonstoichiometric weathering of calcium in juvenile (formerly glaciated) terrane, not to leaching of exchangeable cations by SO 4, because intraregional and cross-regional statistical analysis reveals no effect of atmospherically derived sulfate ion. The median base cation denudation rates (meq m -2 yr -1) for these American lake regions are: Maine granites (108); western Adirondack felsic gneiss (85); Vermilion batholith (42); Idaho batholith (52). The regional rates are high enough to compensate for present wet deposition of acidifying anions except in some vulnerable lake watersheds in the western Adirondacks.

Modeling Laboratory Astrophysics Experiments in the High-Energy-Density Regime Using the CRASH Radiation-Hydrodynamics Model

NASA Astrophysics Data System (ADS)

Grosskopf, M. J.; Drake, R. P.; Trantham, M. R.; Kuranz, C. C.; Keiter, P. A.; Rutter, E. M.; Sweeney, R. M.; Malamud, G.

2012-10-01

The radiation hydrodynamics code developed by the Center for Radiative Shock Hydrodynamics (CRASH) at the University of Michigan has been used to model experimental designs for high-energy-density physics campaigns on OMEGA and other high-energy laser facilities. This code is an Eulerian, block-adaptive AMR hydrodynamics code with implicit multigroup radiation transport and electron heat conduction. CRASH model results have shown good agreement with a experimental results from a variety of applications, including: radiative shock, Kelvin-Helmholtz and Rayleigh-Taylor experiments on the OMEGA laser; as well as laser-driven ablative plumes in experiments by the Astrophysical Collisionless Shocks Experiments with Lasers (ACSEL), collaboration. We report a series of results with the CRASH code in support of design work for upcoming high-energy-density physics experiments, as well as comparison between existing experimental data and simulation results. This work is funded by the Predictive Sciences Academic Alliances Program in NNSA-ASC via grant DEFC52- 08NA28616, by the NNSA-DS and SC-OFES Joint Program in High-Energy-Density Laboratory Plasmas, grant number DE-FG52-09NA29548, and by the National Laser User Facility Program, grant number DE-NA0000850.

Zero-gravity growth of NaF-NaCl eutectics in the NASA Skylab program

NASA Technical Reports Server (NTRS)

Yue, A. S.; Allen, F. G.; Yu, J. G.

1976-01-01

Continuous and discontinuous NaF fibers, embedded in a NaCl matrix, were produced in space and on earth. The production of continuous fibers in a eutectic mixture is attributed to the absence of convection current in the liquid during solidification in space. Image transmission and optical transmittance measurements of transverse sections of the space-grown and earth-grown ingots were made with a light microscope and a spectrometer. It is shown that better optical properties were obtained from samples grown in space. This was attributed to a better alignment of NaF fibers along the ingot axis. A new concept is advanced to explain the phenomenon of transmittance versus far infrared wavelength of the directionally solidified NaCl-NaF eutectic in terms of the two-dimensional Bragg Scattering and the polarization effect of Rayleigh scattering. This concept can be applied to other eutectic systems as long as the index of refraction of the matrix over a range of wavelengths is known. Experimental data are in agreement with the theoretical prediction.

Structural Stability and Electronic Properties of Na2C6O6 for a Rechargeable Sodium-ion Battery

NASA Astrophysics Data System (ADS)

Yamashita, Tomoki; Fujii, Akihiro; Momida, Hiroyoshi; Oguchi, Tamio

2014-03-01

Sodium-ion batteries have been explored as a promising alternative to lithium-ion batteries owing to a significant advantage of a natural abundance of sodium. Recently, it has been reported that disodium rhodizonate, Na2C6O6, exhibit good electrochemical properties and cycle performance as a minor-metal free organic cathode for sodium-ion batteries. However, its crystal structures during discharge/charge cycle still remain unclear. In this work, we theoretically propose feasible crystal structures of Na2+xC6O6 using first principles calculations. A structural phase transition has been found: Na4C6O6 has a different C6O6 packing arrangement from Na2C6O6. Electronic structures of Na2+xC6O6 during discharge/charge cycle are also discussed. Our predictions could be the key to understanding the discharge/charge process of Na2C6O6. Supported by MEXT program ``Elements Strategy Initiative to Form Core Rersearch Center'' (since 2012), MEXT; Ministry of Education Culture, Sports, Science and Technology, Japan.

Abscisic Acid Induction of Vacuolar H+-ATPase Activity in Mesembryanthemum crystallinum Is Developmentally Regulated1

PubMed Central

Barkla, Bronwyn J.; Vera-Estrella, Rosario; Maldonado-Gama, Minerva; Pantoja, Omar

1999-01-01

Abscisic acid (ABA) has been implicated as a key component in water-deficit-induced responses, including those triggered by drought, NaCl, and low- temperature stress. In this study a role for ABA in mediating the NaCl-stress-induced increases in tonoplast H+-translocating ATPase (V-ATPase) and Na+/H+ antiport activity in Mesembryanthemum crystallinum, leading to vacuolar Na+ sequestration, were investigated. NaCl or ABA treatment of adult M. crystallinum plants induced V-ATPase H+ transport activity, and when applied in combination, an additive effect on V-ATPase stimulation was observed. In contrast, treatment of juvenile plants with ABA did not induce V-ATPase activity, whereas NaCl treatment resulted in a similar response to that observed in adult plants. Na+/H+ antiport activity was induced in both juvenile and adult plants by NaCl, but ABA had no effect at either developmental stage. Results indicate that ABA-induced changes in V-ATPase activity are dependent on the plant reaching its adult phase, whereas NaCl-induced increases in V-ATPase and Na+/H+ antiport activity are independent of plant age. This suggests that ABA-induced V-ATPase activity may be linked to the stress-induced, developmentally programmed switch from C3 metabolism to Crassulacean acid metabolism in adult plants, whereas, vacuolar Na+ sequestration, mediated by the V-ATPase and Na+/H+ antiport, is regulated through ABA-independent pathways. PMID:10398716

Comprehension-Driven Program Analysis (CPA) for Malware Detection in Android Phones

DTIC Science & Technology

2015-07-01

COMPREHENSION-DRIVEN PROGRAM ANALYSIS (CPA) FOR MALWARE DETECTION IN ANDROID PHONES IOWA STATE UNIVERSITY JULY 2015 FINAL...DRIVEN PROGRAM ANALYSIS (CPA) FOR MALWARE DETECTION IN ANDROID PHONES Sb. GRANT NUMBER N/A Sc. PROGRAM ELEMENT NUMBER 6 1101E 6. AUTHOR(S) Sd...machine analysis system to detect novel, sophisticated Android malware. (c) An innovative library summarization technique and its incorporation in

Magnetic resonance studies of inorganic oxides and a new pulse programming system for pulsed EMR

NASA Astrophysics Data System (ADS)

Schwartz, Dwight Allen

We have investigated several inorganic oxide systems using nuclear and electron magnetic resonance spectroscopies and also report a new pulse programming system for a pulsed S-band EMR spectrometer. We show in a study of simple perovskites (Ca,Sr,Ba)(Ti,Zr) Osb3 that magic-angle spinning O-17 NMR provides unique, highly-resolved spectra in these materials and gives evidence of being useful as a diagnostic tool in mixed phase materials (Asb{x}Asbsp{1-x}{'})BOsb3. Various used NMR and EMR techniques to study of the commercial borosilicate glasses CGW-3320, CGW-7502, CGW-7740 (Pyrex) and GSC-4, and T-08 (pure silica glass) which had received 5-10 gigarad doses of Co-60 gamma-radiation in the presence and absence of hydrogen gas. We show that B-11, Al-27 and Si-29 MAS NMR spectra contain indications of structural changes in these glasses as a result of large doses of radiation. We also observed the reduction of trace Ti(IV) to Ti(III) when Hsb2 gas was present during irradiation of glass samples. Static NMR and EMR studies in the (Na,Li)POsb3 system indicate a possible mixed alkali effect in the spin-lattice relaxation of Na-23 in NaPOsb3 and Lisb{0.4}Nasb{0.6}POsb3. Static Na-23 NMR studies of NaPOsb3 reveal the presence of different structural or dynamical environments as a function of temperatures between 23-566 C. We have investigated glass and glass fibers of Lisb{0.6}Nasb{0.4}POsb3 and Na(Psb{0.99},Vsb{0.01})Osb3, and show P-31 NMR and EMR evidence that these materials remained structurally isotropic when pulled into fibers. We show that vanadium (in Na(Psb{0.99},Vsb{0.01})Osb3) appears to suppress radiolytic unpaired electron and hole defect production which does take place in nominally vanadium-free NaPOsb3 during small doses of gamma-radiation. We describe hardware and software developed for a pulse programming system for a pulsed S-band EMR spectrometer. This system supports user-programmable automatic independent control of all pulse sequence parameters (pulse and delay durations, and pulse phases). We demonstrate the capabilities of this new system in 2-, 3-, and 4-pulse EMR experiments, and also demonstrate a new software suite for interactive simulation and simulation optimization of electron spin echo envelope modulation (ESEEM) patterns using a genetic algorithm.

Issues and progress in determining background ozone and particle concentrations

NASA Astrophysics Data System (ADS)

Pinto, J. P.

2011-12-01

Exposure to ambient ozone is associated with a variety of health outcomes ranging from mild breathing discomfort to mortality. For the purpose of health risk and policy assessments EPA evaluates the anthropogenic increase in ozone above background concentrations and has defined the North American (NA) background concentration of O3 as that which would occur in the U.S. in the absence of anthropogenic emissions of precursors in the U.S., Canada, and Mexico. Monthly average NA background ozone has been used to evaluate health risks, but EPA and state air quality managers must also estimate day specific ozone background levels for high ozone episodes as part of urban scale photochemical modeling efforts to support ozone regulatory programs. The background concentration of O3 is of more concern than other air pollutants because it typically represents a much larger fraction of observed O3 than do the backgrounds of other criteria pollutants (particulate matter (PM), CO, NO2, SO2). NA background cannot be determined directly from ambient monitoring data because of the influence of NA precursor emissions on formation of ozone within NA. Instead, estimates of NA background O3 have been based on GEOS-Chem using simulations in which NA anthropogenic precursor emissions are zeroed out. Thus, modeled NA background O3 includes contributions from natural sources of precursors (including CH4, NMVOCs, NOx, and CO) everywhere in the world, anthropogenic sources of precursors outside of NA, and downward transport of O3 from the stratosphere. Although monitoring data cannot determine NA background directly, measurements by satellites, aircraft, ozonesondes and surface monitors have proved to be highly useful for identifying sources of background O3 and for evaluating the performance of the GEOS-Chem model. Model simulated NA background concentrations are strong functions of location and season with large inter-day variability and with values increasing with elevation and higher in spring than in summer, and tend to be highest in the Intermountain West during spring. Estimates of annual average NA and other background definitions that have been considered will be presented. Issues associated with modeling background concentrations for both health-risk assessments and for episodic regulatory air quality programs will be discussed, and proposals for new atmospheric measurements and model improvements needed to quantify more accurately background contributions to ozone will also be presented. The views expressed are those of the author and do not necessarily represent the views or policies of the U.S. Environmental Protection Agency.

12 CFR 652.20 - Eligible non-program investments.

Code of Federal Regulations, 2014 CFR

2014-01-01

... dollars. Non-Program Investment Eligibility Criteria Table Asset class Final maturity limit NRSRO issue or... mortgage securities) fully insured or guaranteed by the United States Government or a Government agency. (2) Obligations of Government-sponsored agencies None NA None None. • Government-sponsored agency securities...

Northeastern Area Forest Legacy Program Yearbook 2006

Treesearch

Northeastern Area; State and Private Forestry

2007-01-01

The Forest Legacy Program protects important forestlands by purchasing conservation easements or fee titles from willing landowners whose lands are threatened with conversion to nonforest uses. Forest Legacy properties offer recreational opportunities, watershed protection, timber resources, wildlife habitat, and protection from development. NA-IN-02-07

Reduze - Feynman integral reduction in C++

NASA Astrophysics Data System (ADS)

Studerus, C.

2010-07-01

Reduze is a computer program for reducing Feynman integrals to master integrals employing a Laporta algorithm. The program is written in C++ and uses classes provided by the GiNaC library to perform the simplifications of the algebraic prefactors in the system of equations. Reduze offers the possibility to run reductions in parallel. Program summaryProgram title:Reduze Catalogue identifier: AEGE_v1_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/AEGE_v1_0.html Program obtainable from: CPC Program Library, Queen's University, Belfast, N. Ireland Licensing provisions:: yes No. of lines in distributed program, including test data, etc.: 55 433 No. of bytes in distributed program, including test data, etc.: 554 866 Distribution format: tar.gz Programming language: C++ Computer: All Operating system: Unix/Linux Number of processors used: The number of processors is problem dependent. More than one possible but not arbitrary many. RAM: Depends on the complexity of the system. Classification: 4.4, 5 External routines: CLN ( http://www.ginac.de/CLN/), GiNaC ( http://www.ginac.de/) Nature of problem: Solving large systems of linear equations with Feynman integrals as unknowns and rational polynomials as prefactors. Solution method: Using a Gauss/Laporta algorithm to solve the system of equations. Restrictions: Limitations depend on the complexity of the system (number of equations, number of kinematic invariants). Running time: Depends on the complexity of the system.

Transforming Indigenous Geoscience Education and Research (TIGER)

NASA Astrophysics Data System (ADS)

Berthelote, A. R.

2014-12-01

American Indian tribes and tribal confed­erations exert sovereignty over about 20% of all the freshwater resources in the United States. Yet only about 30 Native American (NA) students receive bachelor's degrees in the geosci­ences each year, and few of those degrees are in the field of hydrology. To help increase the ranks of NA geoscientists,TIGER builds upon the momentum of Salish Kootenai College's newly accredited Hydrology Degree Program. It allows for the development and implementation of the first Bachelor's degree in geosciences (hydrology) at a Tribal College and University (TCU). TIGER integrates a solid educational research-based framework for retention and educational preparation of underrepresented minorities with culturally relevant curriculum and socio-cultural supports, offering a new model for STEM education of NA students. Innovative hydrology curriculum is both academically rigorous and culturally relevant with concurrent theoretical, conceptual, and applied coursework in chemical, biological, physical and managerial aspects of water resources. Educational outcomes for the program include a unique combination of competencies based on industry recognized standards (e.g., National Institute of Hydrologists), input from an experienced External Advisory Board (EAB), and competencies required for geoscientists working in critical NA watersheds, which include unique competencies, such as American Indian Water Law and sovereignty issues. TIGER represents a unique opportunity to capitalize on the investments the geoscience community has already made into broadening the participation of underrepresented minorities and developing a diverse workforce, by allowing SKC to develop a sustainable and exportable program capable of significantly increasing (by 25 to 75%) the National rate of Native American geoscience graduates.

A low-power wide range transimpedance amplifier for biochemical sensing.

PubMed

Rodriguez-Villegas, Esther

2007-01-01

This paper presents a novel low voltage and low power transimpedance amplifier for amperometric potentiostats. The power is optimized by having three different gain settings for different current ranges, which can be programmed with a biasing current. The voltage ranges have been optimized by using FGMOS transistors in a second voltage amplification stage that simultaneously allow for offset calibration as well as independent biasing of the gates. The circuit operates with input currents from 1 pA to 1 microA, with a maximum power supply voltage of 1.5 V and consumes 82.5 nW, 9.825 microW, 47.325 microW for currents varying from (1 pA, 0.25 nA), (0.25 nA, 62.5 nA) and (62.5 nA, 1 microA) respectively.

MELD: A Logical Approach to Distributed and Parallel Programming

DTIC Science & Technology

2012-03-01

0215 5b. GRANT NUMBER N/A 5c. PROGRAM ELEMENT NUMBER 61101E 6. AUTHOR(S) Seth Copen Goldstein Flavio Cruz 5d. PROJECT NUMBER BI20 5e. TASK...Comp. Sci., vol. 50, pp. 1–102, 1987. [33] P. Ló pez, F. Pfenning, J. Polakow, and K. Watkins , “Monadic concurrent linear logic programming,” in

Computer Program for the Calculation of Multicomponent Convective Diffusion Deposition Rates from Chemically Frozen Boundary Layer Theory

NASA Technical Reports Server (NTRS)

Gokoglu, S. A.; Chen, B. K.; Rosner, D. E.

1984-01-01

The computer program based on multicomponent chemically frozen boundary layer (CFBL) theory for calculating vapor and/or small particle deposition rates is documented. A specific application to perimter-averaged Na2SO4 deposition rate calculations on a cylindrical collector is demonstrated. The manual includes a typical program input and output for users.

Enhancing Warfighter Cognitive Abilities with Transcranial Magnetic Stimulation: A Feasibility Analysis

DTIC Science & Technology

2007-06-01

AFRL-HE-WP-TR-2007-0095 Enhancing Warfighter Cognitive Abilities with Transcranial Magnetic Stimulation : a Feasibility Analysis Jeremy T. Nelson...Abilities with Transcranial N/A Magnetic Stimulation : a Feasibility Analysis 5b. GRANTNUMBER N/A 5c. PROGRAM ELEMENT NUMBER 62202F 6. AUTHOR(S) 5d...feasibility of using transcranial magnetic stimulation (TMS) to enhance warfighter cognitive abilities. An extensive literature review was conducted

Revamping Civilian Leadership Development in the Marine Corps

DTIC Science & Technology

2012-04-09

Leadership Development in the Marine NIA Corps Sb. GRANT NUMBER NIA Sc. PROGRAM ELEMENT NUMBER N/A 6. AUTHOR(S) Sd. PROJECf NUMBER Major Jose E. Almazan...DISTRIBUTION I AVAILABILITY STATEMENT Unlimited 13. SUPPLEMENTARY NOTES N/A 14. ABSTRACT: The Marine Corps should be investing more in civilian leadership ...development and must make its use involuntary for career progression. This study endeavors to resolve whether revamping civilian leadership

State, Foreign Operations, and Related Programs: FY2011 Budget and Appropriations

DTIC Science & Technology

2011-04-22

and Pakistan. The Obama Administration has also largely sustained Bush Administration investments in global health and HIV/AIDS treatment , though its...funding. The discrepancy apparently relates to the treatment of the Pakistan Counterinsurgency Contingency Fund and a portion of Foreign Military...230 +37% Neglected Tropical Diseases — $155 N/A Nutrition — $231 N/A Other Public Health Threats $128 $225 +76% Polio $32 $33 +3% Trade Capacity

LANL: Weapons Infrastructure Briefing to Naval Reactors, July 18, 2017

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chadwick, Frances

Presentation slides address: The Laboratory infrastructure supports hundreds of high hazard, complex operations daily; LANL’s unique science and engineering infrastructure is critical to delivering on our mission; LANL FY17 Budget & Workforce; Direct-Funded Infrastructure Accounts; LANL Org Chart; Weapons Infrastructure Program Office; The Laboratory’s infrastructure relies on both Direct and Indirect funding; NA-50’s Operating, Maintenance & Recapitalization funding is critical to the execution of the mission; Los Alamos is currently executing several concurrent Line Item projects; Maintenance @ LANL; NA-50 is helping us to address D&D needs; We are executing a CHAMP Pilot Project at LANL; G2 = Main Toolmore » for Program Management; MDI: Future Investments are centered on facilities with a high Mission Dependency Index; Los Alamos hosted first “Deep Dive” in November 2016; Safety, Infrastructure & Operations is one of the most important programs at LANL, and is foundational for our mission success.« less

Modeling Laser-Driven Laboratory Astrophysics Experiments Using the CRASH Code

NASA Astrophysics Data System (ADS)

Grosskopf, Michael; Keiter, P.; Kuranz, C. C.; Malamud, G.; Trantham, M.; Drake, R.

2013-06-01

Laser-driven, laboratory astrophysics experiments can provide important insight into the physical processes relevant to astrophysical systems. The radiation hydrodynamics code developed by the Center for Radiative Shock Hydrodynamics (CRASH) at the University of Michigan has been used to model experimental designs for high-energy-density laboratory astrophysics campaigns on OMEGA and other high-energy laser facilities. This code is an Eulerian, block-adaptive AMR hydrodynamics code with implicit multigroup radiation transport and electron heat conduction. The CRASH model has been used on many applications including: radiative shocks, Kelvin-Helmholtz and Rayleigh-Taylor experiments on the OMEGA laser; as well as laser-driven ablative plumes in experiments by the Astrophysical Collisionless Shocks Experiments with Lasers (ACSEL) collaboration. We report a series of results with the CRASH code in support of design work for upcoming high-energy-density physics experiments, as well as comparison between existing experimental data and simulation results. This work is funded by the Predictive Sciences Academic Alliances Program in NNSA-ASC via grant DEFC52- 08NA28616, by the NNSA-DS and SC-OFES Joint Program in High-Energy-Density Laboratory Plasmas, grant number DE-FG52-09NA29548, and by the National Laser User Facility Program, grant number DE-NA0000850.

Major Management Challenges and Program Risks. Department of State

DTIC Science & Technology

2001-01-01

Major Management Challenges and Program Risks Department of StateGAO-01-252 Form SF298 Citation Data Report Date ("DD MON YYYY") 00JAN2001 Report...Type N/A Dates Covered (from... to) ("DD MON YYYY") Title and Subtitle Major Management Challenges and Program Risks Department of State Contract or...special series, first issued in January 1999, entitled the Performance and Accountability Series: Major Management Challenges and Program Risks . In

Major Management Challenges and Program Risks. Department of the Interior

DTIC Science & Technology

2001-01-01

Major Management Challenges and Program Risks Department of the InteriorGAO-01-249 Report Date ("DD MON YYYY") 00JAN2001 Report Type N/A Dates...Covered (from... to) ("DD MON YYYY") Title and Subtitle Major Management Challenges and Program Risks Department of the Interior Contract or Grant...first issued in January 1999, entitled the Performance and Accountability Series: Major Management Challenges and Program Risks . In that series, GAO

Deradicalization or Disengagement : A Framework for Encouraging Jihad Abandonment

DTIC Science & Technology

2016-06-10

resulted in entire group disengagement, while the German HAYAT Program and Saudi Counseling Program seek individual de-radicalization/disengagement... Counseling Y Optional N/A Y Y Family Counseling N Y N Y Y Practical Support Measures Y Y Y Y Y Disengage Guarantee – Type Y - Family N Y – Group N...disengagement. The U.S. could easily support religious counseling in de-radicalization programs in partner nations overseas. Group or Individual Programs

Montmorillonite-supported Pd0, Fe0, Cu0 and Ag0 nanoparticles: Properties and affinity towards CO2

NASA Astrophysics Data System (ADS)

Bouazizi, Nabil; Barrimo, Diana; Nousir, Saadia; Ben Slama, Romdhane; Roy, René; Azzouz, Abdelkrim

2017-04-01

This study reports the carbon dioxide (CO2) adsorption on montmorillonite (NaMt) incorporating Cu0, Fe0, Pd0 and Ag0 as metallic nanoparticles (MNPs). The changes in structural, textural, morphological and adsorption properties of the resulting materials (NaMt-MNPs) were investigated. Electron microscopy and X-ray diffraction showed that dispersion of fine MNPs occurs mainly within the interlayer space of NaMt, producing a slight structure expansion. This was accompanied by a visible enhancement of the affinity towards CO2, as supported by thermal programmed desorption measurements. NaMt-MNPs displayed high CO2 retention capacity (CRC) of ca. 657 μmol/g for NaMt-Cu as compared to NaMt. This was explained in terms of increased number of available adsorption sites due to enlarged interlayer spaces caused by MNP insertion. The differences in CO2 adsorption capacities clearly demonstrate the key role of MNPs in improving the surface properties and adsorption capacity. The results reported herein open new prospects for clay supported metal nanoparticles as efficient adsorbents for CO2.

Brief report: ectopic expression of NUP98-HOXA10 augments erythroid differentiation of human embryonic stem cells.

PubMed

Ji, Junfeng; Risueño, Ruth M; Hong, Seokho; Allan, David; Rosten, Patty; Humphries, Keith; Bhatia, Mickie

2011-04-01

Hox genes encode highly conserved transcription factors that have been implicated in hematopoietic development and self-renewal of hematopoietic stem cells (HSCs) and hematopoietic development. The potency of NUP98-HOXA10hd (NA10) on adult murine bone marrow HSC self-renewal prompted us to examine its effect on specification and proliferation of hematopoietic cells derived from human embryonic stem cells (hESCs). Here, we demonstrate that expression of NA10 in hESCs influences the hematopoietic differentiation program. The specific effect of NA10 is dependent on the developmental stage of hematopoietic emergence from hESCs. Overexpression of NA10 in either undifferentiated hESCs or early hemogenic precursors augmented the frequency of CD45(-) GlycophorinA(+) cells and erythroid progenitors (blast-forming unit-erythrocyte). In contrast, targeted NA10 expression in primitive CD34+ cells committed to the hematopoietic lineage had no effect on erythropoietic capacity but instead increased hematopoietic progenitor proliferation. Our study reveals a novel neomorphic effect of NA10 in early human erythroid development from pluripotent stem cells. Copyright © 2011 AlphaMed Press.

French MALE UAV Program

DTIC Science & Technology

2003-09-02

ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) MoD- France 8...1French Air Force MINISTÈRE DE LA DÉFENSE 1 SIDM CONOPS 2 FAF IMAGERY ARCHITECTURE 3 FUTURE FRENCH MALE UAV PROGRAM FRENCH MALE UAV PROGRAM Report...2. REPORT TYPE N/A 3. DATES COVERED - 4. TITLE AND SUBTITLE French Male UAV Program 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM

An exploratory study of the effect of regular aquatic exercise on the function of neutrophils from women with fibromyalgia: role of IL-8 and noradrenaline.

PubMed

Bote, M E; García, J J; Hinchado, M D; Ortega, E

2014-07-01

Fibromyalgia (FM) syndrome is associated with elevated systemic inflammatory and stress biomarkers, and an elevated innate cellular response mediated by monocytes and neutrophils. Exercise is accepted as a good non-pharmacological therapy for FM. We have previously found that regular aquatic exercise decreases the release of inflammatory cytokines by monocytes from FM patients. However, its effects on the functional capacity of neutrophils have not been studied. The aim of the present exploratory study was to evaluate, in 10 women diagnosed with FM, the effect of an aquatic exercise program (8months, 2sessions/week, 60min/session) on their neutrophils' function (phagocytic process), and on IL-8 and NA as potential inflammatory and stress mediators, respectively. A control group of 10 inactive FM patients was included in the study. After 4months of the exercise program, no significant changes were observed in neutrophil function (chemotaxis, phagocytosis, or fungicidal capacity) or in IL-8 and NA. However, at the end of the exercise program (8months), a neuro-immuno-endocrine adaptation was observed, manifested by a significant decrease to values below those in the basal state in neutrophil chemotaxis, IL-8, and NA. No significant seasonal changes in these parameters were observed during the same period in the group of non-exercised FM patients. After the 8months of the exercise program, the FM patients had lower concentrations of IL-8 and NA together with reduced chemotaxis of neutrophils compared with the values determined in the same month in the control group of non-exercised FM women. These results suggest that "anti-inflammatory" and "anti-stress" adaptations may be contributing to the symptomatic benefits that have been attributed to regular aquatic exercise in FM syndrome, as was corroborated in the present study by the scores on the Fibromyalgia Impact Questionnaire. Copyright © 2013 Elsevier Inc. All rights reserved.

Eagle-Picher Industries Sodium Sulfur Program

NASA Technical Reports Server (NTRS)

Silvey, Ronald L.

1993-01-01

Viewgraphs of the sodium sulfur program are presented. Sodium sulfur low earth orbit (LEO) cells are described. Topics covered include cell sizes, areas of improvement, and NaS cell testing. Sodium sulfur cell and battery designs continue to evolve with significant improvement demonstrated in resistance, rechargeability, cycle life, energy density, and electrolyte characterization.

76 FR 54426 - Submission for OMB Review; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-01

... Enhancement Needs Assessment Survey Program. OMB Control Number: 0694-0083. Form Number(s): N/A. Type of...,400. Number of Respondents: 2,400. Average Hours per Response: 1 hour. Needs and Uses: The Defense... their abilities to meet defense program needs. The information collected from voluntary surveys will be...

Success Models for Gifted Native Students.

ERIC Educational Resources Information Center

Sing, David K.

The Center for Gifted and Talented Native Hawaiian Children at the University of Hawaii at Hilo aims to develop culturally appropriate gifted and talented programs and identification procedures for Native Hawaiian children. Every Center program incorporates four elements of the Na Pua No'eau model: talent enhancement, self-esteem development,…

Curriculum Guidelines: Native Hawaiian Curriculum Development Project.

ERIC Educational Resources Information Center

Kawakami, Alice J.; Aton, Kanani; Glendon, Crystal; Stewart, Roxane

The Na'imiloa (seeker of knowledge) program provides educational enrichment opportunities to gifted underachieving Native Hawaiian high school students. Developed by the University of Hawaii at Hilo and selected high schools, the program was designed to build upon students' talents, develop their self-esteem, and develop an awareness and…

77 FR 46632 - Closed Captioning of Internet Protocol-Delivered Video Programming: Implementation of the Twenty...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-06

... video programming and apparatus closed captioning requirements. This notice is consistent with the Order... Delivered Using Internet Protocol, and Apparatus Closed Caption Requirements. Form Number: N/A. Respondents... rules governing the closed captioning capabilities of certain apparatus on which consumers view video...

Producibility in Ship Design

DTIC Science & Technology

1989-09-01

INNOVATION MARINE INDUSTRY STANDARDS WELDING INDUSTRIAL ENGINEERING EDUCATION AND TRAINING THE NATIONAL SHIPBUILDING RESEARCH PROGRAM September 1989 NSRP 0310...SEP 1989 2. REPORT TYPE N/A 3. DATES COVERED - 4. TITLE AND SUBTITLE The National Shipbuilding Research Program 1989 Ship Production Symposium...Paper No. 3: Producibility in Ship Design 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e

Food sources of dietary sodium in the Japanese adult population: the international study of macro-/micronutrients and blood pressure (INTERMAP).

PubMed

Okuda, Nagako; Okayama, Akira; Miura, Katsuyuki; Yoshita, Katsushi; Saito, Shigeyuki; Nakagawa, Hideaki; Sakata, Kiyomi; Miyagawa, Naoko; Chan, Queenie; Elliott, Paul; Ueshima, Hirotsugu; Stamler, Jeremiah

2017-04-01

It is often reported that Na intake levels are higher in Japan than in western countries. Detailed analysis of food intake and its association with Na intake are necessary for supporting further decreases in Na consumption in Japan. We investigated the association between Na and food intake by food group using data from the Japanese participants of the INTERMAP Study. Results from the Japanese participants of the INTERMAP Study who did not use antihypertensive medication and/or consume a reduced Na diet were used (531 men and 518 women, aged 40-59 years), obtained from four 24-h dietary recalls and two 24-h urine collections from each participant. We developed a classification system with 46 food group classifications; food consumption and Na intake from these groups were compared across quartiles of participants determined by 24-h urinary Na excretion per unit of body weight (UNa/BW). Average daily Na intake from Japanese high-Na foods was 2552 mg/day. Participants with a higher UNa/BW consumed a significantly greater amount of high-Na Japanese foods, such as salted fish (P = 0.001) and miso soup (P < 0.001). They also had greater amount of rice (P = 0.001). Participants with lower UNa/BW consumed a significantly greater amount of western foods, such as bread (P < 0.001) and milk and dairy products (P < 0.001). Detailed analyses of various Japanese and western food intakes in addition to Na intake were performed. These results can be used to help draw up effective programs for the reduction in Na intake and prevention of prehypertension/hypertension in the Japanese population.

Sodium sulfate: Vaporization thermodynamics and role in corrosive flames

NASA Technical Reports Server (NTRS)

Kohl, F. J.

1975-01-01

Gaseous species over liquid Na2SO4 were identified by the technique of molecular beam mass spectrometry. The heat and entropy of vaporization of the Na2SO4 molecule were measured directly. Comparisons of the experimental entropy with values calculated using various molecular parameters were used to estimate the molecular structure and vibrational frequencies. The thermodynamic properties of gaseous and condensed phase Na2SO4, along with additional pertinent species, were used in a computer program to calculate equilibrium flame compositions and temperatures for representative turbine engine and burner rig flames. Compositions were calculated at various fuel-to-oxidant ratios with additions of sulfur to the fuel and the components of sea salt to the intake air. Temperatures for condensation of Na2SO4 were obtained as a function of sulfur and sea salt concentrations.

Investigations into the Settlement and Attachment of Biofouling Marine Invertebrates

DTIC Science & Technology

2015-12-17

attachment of biofouling marine invertebrates 5a. CONTRACT NUMBER N00014-12-1 -0432 5b. GRANT NUMBER n/a 5c. PROGRAM ELEMENT NUMBER n/a 6...larval settlement in a variety of marine invertebrate species, including B. neritina. Light also inhibits B. neritina larval settlement, yet the...underlying mechanisms by which light and adrenergic compounds exert their effects on larvae are largely unknown. Octopamine is considered the invertebrate

Control of xylem Na+ loading and transport to the shoot in rice and barley as a determinant of differential salinity stress tolerance.

PubMed

Ishikawa, Tetsuya; Shabala, Sergey

2018-05-15

Control of xylem Na + loading has often been named as the essential components of salinity tolerance mechanism. However, it is less clear to what extent the difference in this trait may determine differential salinity tolerance between species. In this study barley (Hordeum vulgare L. cv. CM72) and rice (Oryza sativa L. cv Dongjin) plants were grown under two levels of salinity. Na + and K + concentrations in the xylem sap, and shoot and root tissues were measured at different time points after stress onset. Salt-exposed rice plants prevented xylem Na + loading for several days, but failed to control this process in the longer term, ultimately resulting in a massive Na + shoot loading. Barley plants quickly increased xylem Na + concentration and its delivery to the shoot (most likely for the purpose of osmotic adjustment) but were able to reduce this process later on, keeping most of accumulated Na + in the root, thus maintaining non-toxic shoot Na + level. Rice plants increased shoot K + concentration, while barley plants maintained higher root K + concentration. Control of xylem Na + loading is remarkably different between rice and barley; this difference may differentiate the extent of the salinity tolerance between species. This trait should be investigated in more details to be used in the breeding programs aimed to improve salinity tolerance in crops. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

Improving Hospital-Wide Early Resource Allocation through Machine Learning.

PubMed

Gartner, Daniel; Padman, Rema

2015-01-01

The objective of this paper is to evaluate the extent to which early determination of diagnosis-related groups (DRGs) can be used for better allocation of scarce hospital resources. When elective patients seek admission, the true DRG, currently determined only at discharge, is unknown. We approach the problem of early DRG determination in three stages: (1) test how much a Naïve Bayes classifier can improve classification accuracy as compared to a hospital's current approach; (2) develop a statistical program that makes admission and scheduling decisions based on the patients' clincial pathways and scarce hospital resources; and (3) feed the DRG as classified by the Naïve Bayes classifier and the hospitals' baseline approach into the model (which we evaluate in simulation). Our results reveal that the DRG grouper performs poorly in classifying the DRG correctly before admission while the Naïve Bayes approach substantially improves the classification task. The results from the connection of the classification method with the mathematical program also reveal that resource allocation decisions can be more effective and efficient with the hybrid approach.

Cellular mechanisms to survive salt in the halophyte Cakile maritima.

PubMed

Arbelet-Bonnin, Delphine; Ben Hamed-Laouti, Ibtissem; Laurenti, Patrick; Abdelly, Chedly; Ben Hamed, Karim; Bouteau, François

2018-07-01

We recently identified two behaviours in cultured cells of the salt accumulating halophyte Cakile maritima: one related to a sustained depolarization due to Na + influx through the non-selective cation channels leading to programmed cell death of these cells, a second one related to a transient depolarization allowing cells to survive (Ben Hamed-Laouti, 2016). In this study, we considered at the cellular level mechanisms that could participate to the exclusion of Na + out of the cell and thus participate in the regulation of the internal contents of Na + and cell survival. Upon addition of NaCl in the culture medium of suspension cells of C. maritima, we observed a rapid influx of Na + followed by an efflux dependent of the activity of plasma membrane H + -ATPases, in accordance with the functioning of a Na + /H + antiporter and the ability of some cells to repolarize. The Na + efflux was shown to be dependent on Na + -dependent on Ca 2+ influx like the SOS1 Na + /H + antiporter. We further could observe in response to salt addition, an early production of singlet oxygen ( 1 O 2 ) probably due to peroxidase activities. This early 1 O 2 production seemed to be a prerequisite to the Na + efflux. Our findings suggest that in addition to the pathway leading to PCD (Ben Hamed-Laouti, 2016), a second pathway comprising an SOS-like system could participate to the survival of a part of the C. maritima cultured cells challenged by salt stress. Copyright © 2018 Elsevier B.V. All rights reserved.

77 FR 4084 - Prices for 2012 Infantry Soldier Silver Dollar and 2012 Star-Spangled Banner Commemorative Coin...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-26

... 2012 Star- Spangled Banner Commemorative Coin Program Products AGENCY: United States Mint, Department... Infantry Soldier Silver Dollar and 2012 Star-Spangled Banner Commemorative Coin Program products. Prices.... Silver Dollar. 2012 Infantry Soldier Silver Dollar N/A $61.95. Defenders of Freedom Set. 2012 Star...

76 FR 78621 - Notice of Submission for OMB Review

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-19

... (TEACH Grant Program) Agreement to Serve. OMB Control Number: 1845-0083. Agency Form Number(s): N/A... College and Higher Education (TEACH) Grant Program under Part A of the Higher Education Act of 1965, as... Education (TEACH) Grant, a student must sign an Agreement to Serve. A new Agreement to Serve must be signed...

HVEPS Scramjet-Driven MHD Power Demonstration Test Results (Preprint)

DTIC Science & Technology

2007-06-01

an outer annulus which provides the flow passage for the liquid NaK. Final fabrication and assembly of the seeding system was completed at UTRC as...ABSTRACT The Air Force sponsored Hypersonic Vehicle Electric Power System (HVEPS) program was a research program to develop scramjet driven...magnetohydrodynamic (MHD) power for an advanced high power, airborne electric power system . This program has been active for the past five years with various

Expression, purification, and characterization of the Necator americanus aspartic protease-1 (Na-APR-1 (M74)) antigen, a component of the bivalent human hookworm vaccine.

PubMed

Seid, Christopher A; Curti, Elena; Jones, R Mark; Hudspeth, Elissa; Rezende, Wanderson; Pollet, Jeroen; Center, Lori; Versteeg, Leroy; Pritchard, Sonya; Musiychuk, Konstantin; Yusibov, Vidadi; Hotez, Peter J; Bottazzi, Maria Elena

2015-01-01

Over 400 million people living in the world's poorest developing nations are infected with hookworms, mostly of the genus Necator americanus. A bivalent human hookworm vaccine composed of the Necator americanus Glutathione S-Transferase-1 (Na-GST-1) and the Necator americanus Aspartic Protease-1 (Na-APR-1 (M74)) is currently under development by the Sabin Vaccine Institute Product Development Partnership (Sabin PDP). Both monovalent vaccines are currently in Phase 1 trials. Both Na-GST-1 and Na-APR-1 antigens are expressed as recombinant proteins. While Na-GST-1 was found to express with high yields in Pichia pastoris, the level of expression of Na-APR-1 in this host was too low to be suitable for a manufacturing process. When the tobacco plant Nicotiana benthamiana was evaluated as an expression system, acceptable levels of solubility, yield, and stability were attained. Observed expression levels of Na-APR-1 (M74) using this system are ∼300 mg/kg. Here we describe the achievements and obstacles encountered during process development as well as characterization and stability of the purified Na-APR-1 (M74) protein and formulated vaccine. The expression, purification and analysis of purified Na-APR-1 (M74) protein obtained from representative 5 kg reproducibility runs performed to qualify the Na-APR-1 (M74) production process is also presented. This process has been successfully transferred to a pilot plant and a 50 kg scale manufacturing campaign under current Good Manufacturing Practice (cGMP) has been performed. The 50 kg run has provided a sufficient amount of protein to support the ongoing hookworm vaccine development program of the Sabin PDP.

French Interim MALE UAV Program

DTIC Science & Technology

2003-09-02

MINISTÈRE DE LA DÉFENSE June, 13th 2002 Lcl Monsterleet FAF Staff J. Caron EADS S&DE-ISR FRENCH INTERIM MALE UAV PROGRAM 4 INDUSTRIAL STATUS Report...2003 2. REPORT TYPE N/A 3. DATES COVERED - 4. TITLE AND SUBTITLE French Interim Male UAV Program 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c...PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) EADS

U.S. Department of Agriculture: Resolution of Discrimination Complaints Involving Farm Credit and Payment Programs

DTIC Science & Technology

2001-04-12

2There have also been long-standing concerns about USDA’s treatment of minority employees . As requested, however, this report focuses on program -related... program participants and employees . Form SF298 Citation Data Report Date ("DD MON YYYY") 00MAY2001 Report Type N/A Dates Covered (from... to) ("DD MON...Indianswho were denied benefits under the U.S. Department of Agricultures (USDA) farm assistance programs 1 have been a long-standing issue. Compounding

Management Study of the Office of the Secretary of Defense.

DTIC Science & Technology

1987-10-01

work . If DoD is unable to acquire an individual with similar broad experience in both the C3 and Intelligence areas, consideration should be given to...ORGANIZATION (If applicable) N/A N/A 8c. ADDRESS (City, State, and ZIP Code) 10. SOURCE OF FUNDING NUMBERS PROGRAM N PROJECT TASK WORK UNIT ELMN...political-military assinumptions, apd improve civilian control over operations planning. Concerns about the sensitivity of the plans should be balanced

Integrated Reconfigurable Intelligent Systems (IRIS) for Complex Naval Systems

DTIC Science & Technology

2010-02-21

RKF45] and Adams Variable Step- Size Predictor - Corrector methods). While such algorithms naturally are usually used to numerically solve differential...verified by yet another function call. Due to their nature, such methods are referred to as predictor - corrector methods. While computationally expensive...CONTRACT NUMBER N00014-09- C -0394 5b. GRANT NUMBER N/A 5c. PROGRAM ELEMENT NUMBER N/A 6. Author(s) Dr. Dimitri N. Mavris Dr. Yongchang Li 5d

Mission Planning System Increment 5 (MPS Inc 5)

DTIC Science & Technology

2016-03-01

DoD - Department of Defense DoDAF - DoD Architecture Framework FD - Full Deployment FDD - Full Deployment Decision FY - Fiscal Year IA...Alternative Selected (Funds First Obligated (FFO)) (O/T) : Mar 2013 / Mar 2013 • MS B (O/T) : Apr 2012 / Apr 2012 • MS C (O/T) : N/A / N/A • FDD (O/T...Deployed Software Intensive Program" as described in the DOD Instruction 5000.02, January 7, 2015. 4. FDD provides approval to field the

Recent Advances and Perspectives on Nonadiabatic Mixed Quantum-Classical Dynamics.

PubMed

Crespo-Otero, Rachel; Barbatti, Mario

2018-05-16

Nonadiabatic mixed quantum-classical (NA-MQC) dynamics methods form a class of computational theoretical approaches in quantum chemistry tailored to investigate the time evolution of nonadiabatic phenomena in molecules and supramolecular assemblies. NA-MQC is characterized by a partition of the molecular system into two subsystems: one to be treated quantum mechanically (usually but not restricted to electrons) and another to be dealt with classically (nuclei). The two subsystems are connected through nonadiabatic couplings terms to enforce self-consistency. A local approximation underlies the classical subsystem, implying that direct dynamics can be simulated, without needing precomputed potential energy surfaces. The NA-MQC split allows reducing computational costs, enabling the treatment of realistic molecular systems in diverse fields. Starting from the three most well-established methods-mean-field Ehrenfest, trajectory surface hopping, and multiple spawning-this review focuses on the NA-MQC dynamics methods and programs developed in the last 10 years. It stresses the relations between approaches and their domains of application. The electronic structure methods most commonly used together with NA-MQC dynamics are reviewed as well. The accuracy and precision of NA-MQC simulations are critically discussed, and general guidelines to choose an adequate method for each application are delivered.

Oxidation of MnO(100) and NaMnO2 formation: Characterization of Mn2+ and Mn3+ surfaces via XPS and water TPD

NASA Astrophysics Data System (ADS)

Feng, Xu; Cox, David F.

2018-09-01

The oxidation of clean and Na precovered MnO(100) has been investigated by X-ray photoelectron spectroscopy (XPS), low energy electron diffraction (LEED) and temperature programmed desorption (TPD) of adsorbed water. XPS results indicate that Mn3O4-like and Mn2O3-like surfaces can be formed by various oxidation treatments of clean and nearly-stoichiometric MnO(100), while a NaMnO2-like surface can be produced by the oxidation of MnO(100) pre-covered with multilayers of metallic Na. Water TPD results indicate that water adsorption/desorption is sensitive to the available oxidation states of surface Mn cations, and can be used to distinguish between surfaces exposing Mn2+and Mn3+ cations, or a combination of these oxidation states. Carbon dioxide and water TPD results from the NaMnO2-like surface indicate that pre-adsorbed water blocks the uptake of CO2, while water displaces pre-adsorbed CO2. No indication of a strong reactive interaction is observed between CO2, water and the NaMnO2-like surface under the conditions of our study.

Lattice dynamics of Cs2NaYbF6 and Cs2NaYF6 elpasolites: Ab initio calculation

NASA Astrophysics Data System (ADS)

Chernyshev, V. A.; Petrov, V. P.; Nikiforov, A. E.; Zakir'yanov, D. O.

2015-06-01

The ab initio calculations of the crystal structure and the phonon spectrum of Cs2NaYbF6 and Cs2NaYF6 crystals with the elpasolite structure have been performed. The frequencies and types of fundamental vibrations have been determined. The calculations have been performed in the framework of the density functional theory using the molecular orbital method with hybrid functionals in the CRYSTAL09 program developed for the simulation of periodic structures. The outer 5 s and 5 p shells of the rare-earth ion have been described in Gaussian-type basis sets. The influence of inner shells, including 4 f electron shells, on the outer shells has been described using the pseudopotential. It has been shown that this approach allows the description of the phonon spectrum with the inclusion of the splitting of the longitudinal and transverse optical modes.

Comparative sodium transport patterns provide clues for understanding salinity and metal responses in aquatic insects.

PubMed

Scheibener, S A; Richardi, V S; Buchwalter, D B

2016-02-01

The importance of insects in freshwater ecosystems has led to their extensive use in ecological monitoring programs. As freshwater systems are increasingly challenged by salinization and metal contamination, it is important to understand fundamental aspects of aquatic insect physiology (e.g., osmoregulatory processes) that contribute to insect responses to these stressors. Here we compared the uptake dynamics of Na as NaCl, NaHCO3 and Na2SO4 in the caddisfly Hydropsyche betteni across a range of Na concentrations (0.06-15.22 mM) encompassing the vast majority of North American freshwater ecosystems. Sulfate as the major anion resulted in decreased Na uptake rates relative to the chloride and bicarbonate salts. A comparison of Na (as NaHCO3) turnover rates in the caddisfly Hydropsyche sparna and the mayfly Maccaffertium sp. revealed different patterns in the 2 species. Both species appeared to tightly regulate their whole body sodium concentrations (at ∼47±1.8 μmol/g wet wt) across a range of Na concentrations (0.06-15.22 mM) over 7 days. However, at the highest Na concentration (15.22 mM), Na uptake rates in H. sparna (419.1 μM Na g(-1) hr(-1) wet wt) appeared close to saturation while Na uptake rates in Maccaffertium sp. were considerably faster (715 g μM Na g(-1) hr(-1) wet wt) and appeared to not be close to saturation. Na efflux studies in H. sparna revealed that loss rates are commensurate with uptake rates and are responsive to changes in water Na concentrations. A comparison of Na uptake rates (at 0.57 mM Na) across 9 species representing 4 major orders (Ephemeroptera, Plecoptera, Trichoptera and Diptera) demonstrated profound physiological differences across species after accounting for the influence of body weight. Faster Na uptake rates were associated with species described as being sensitive to salinization in field studies. The metals silver (Ag) and copper (Cu), known to be antagonistic to Na uptake in other aquatic taxa did not generally exhibit this effect in aquatic insects. Ag only reduced Na uptake at extremely high concentrations, while Cu generally stimulated Na uptake in aquatic insects, rather than suppress it. These results help explain the lack of insect responses to dissolved metal exposures in traditional toxicity testing and highlight the need to better understand fundamental physiological processes in this ecologically important faunal group. Copyright © 2015 Elsevier B.V. All rights reserved.

Standard Missile-6 (SM-6)

DTIC Science & Technology

2016-12-01

and Maintenance ACAT - Acquisition Category ADM - Acquisition Decision Memorandum APB - Acquisition Program Baseline APPN - Appropriation APUC...Acquisition Program MILCON - Military Construction N/A - Not Applicable O&M - Operations and Maintenance ORD - Operational Requirements Document OSD...RMS) Contractor Location: 1151 Hermans Road Tucson, AZ 85756 Contract Number: N00024-13-C-5407/0 Contract Type: Firm Fixed Price (FFP) Award Date

Repair, Evaluation, Maintenance, and Rehabilitation Research Program. Lock Accident Study

DTIC Science & Technology

1990-09-01

ZIP Code) 10 . SOURCE OF FUNDIN6 NUMBERS -- . ;_ PROGRAM PROJECT TASK WORK UNIT Washington, DC 20314-1000 ELEMENT NO. NO. NO. . NO. 11. TITLE (1 eNy...miwcrwA; I ’+an na SECURITY CLASSIFICATION OF THIS PAGE 10 . WORK UNIT ACCESSION NO. (Continued). Funding provided by Repair, Evaluation, Maintenance, and... 10 PM S ............................................................... 10 District Records

Positive affect moderates the effect of negative affect on cardiovascular disease-related hospitalizations and all-cause mortality after cardiac rehabilitation.

PubMed

Meyer, Fiorenza Angela; von Känel, Roland; Saner, Hugo; Schmid, Jean-Paul; Stauber, Stefanie

2015-10-01

Little is known as to whether negative emotions adversely impact the prognosis of patients who undergo cardiac rehabilitation. We prospectively investigated the predictive value of state negative affect (NA) assessed at discharge from cardiac rehabilitation for prognosis and the moderating role of positive affect (PA) on the effect of NA on outcomes. A total of 564 cardiac patients (62.49 ± 11.51) completed a comprehensive three-month outpatient cardiac rehabilitation program, filling in the Global Mood Scale (GMS) at discharge. The combined endpoint was cardiovascular disease (CVD)-related hospitalizations plus all-cause mortality at follow-up. Cox regression models estimated the predictive value of NA, as well as the moderating influence of PA on outcomes. Survival models were adjusted for sociodemographic factors, traditional cardiovascular risk factors, and severity of disease. During a mean follow-up period of 3.4 years, 71 patients were hospitalized for a CVD-related event and 15 patients died. NA score (range 0-20) was a significant and independent predictor (hazard ratio (HR) 1.091, 95% confidence interval (CI) 1.012-1.175; p = 0.023) with a three-point higher level in NA increasing the relative risk by 9.1%. Furthermore, PA interacted significantly with NA (p < 0.001). The relative risk of poor prognosis with NA was increased in patients with low PA (p = 0.012) but remained unchanged in combination with high PA (p = 0.12). The combination of NA with low PA was particularly predictive of poor prognosis. Whether reduction of NA and increase of PA, particularly in those with high NA, improves outcome needs to be tested. © The European Society of Cardiology 2014.

The National Shipbuilding Research Program. Survey of Air and Water Quality Pollution Prevention and Control Technology Used in Shipyards and Similar Industries

DTIC Science & Technology

1998-01-09

vehicle washing 3. TSP and citric acid for bilge cleaning 1. no capture and filtration of weld fumes 8 1. black beauty abrasives 2...treatment 1. not treated N/A 12 N/A 1. treated on-site. with gravity oil water separator, acid cracking of the emulsion layer and parallel...less energy-intensive treatment technologies such as constructed wetlands for sewage treatment and anoxic limestone drains for acid mine drainage

Installation Restoration Program. Volume 2. 110th Fighter Group Michigan Air National Guard, W.K. Kellogg Memorial Airport, Battle Creek, Michigan

DTIC Science & Technology

1993-11-01

RECOMMENDATIONS SECTION 7 REFERENCES APPENDIX A MONITORING WELL CONSTRUCTION RECORDS AND BORING LOGS APPENDIX B SOIL BORING LOGS 3 APPENDIX C ...0.25 .o000 2- C *LUOEITNYL VINYL ETNEE NA i2/o/U NP 0. 131.0ICNLORMTNMIE NA 12/OS/IS 0.35 0.0S 1.000 DIOCULUSUGRTNAN NA 12/OS/US a 0.45 1.000 ¶ ,2...12l/Sm a 10.001011 kS kfue(K)I m ot~b 12/09/ 12/fl/U a 10.00 1.005 ugejpvu 12/09/ tZ/3U 0 10.0 1 .M E, I c . ce 4Z- CR0ESFENGINEERING SCIENCE 135-073

Major Management Challenges and Program Risks. Department of the Treasury

DTIC Science & Technology

2001-01-01

Major Management Challenges and Program Risks Department of the TreasuryGAO-01-254 Form SF298 Citation Data Report Date ("DD MON YYYY") 00JAN2001...Report Type N/A Dates Covered (from... to) ("DD MON YYYY") Title and Subtitle Major Management Challenges and Program Risks Department of the...High Risks (GAO-01-159SP), in November 2000.This report addresses the major performance and accountability challenges facing the Department of the

Major Management Challenges and Program Risks. Department of Labor

DTIC Science & Technology

2001-01-01

Major Management Challenges and Program Risks Department of LaborGAO-01-251 Form SF298 Citation Data Report Date ("DD MON YYYY") 00JAN2001 Report...Type N/A Dates Covered (from... to) ("DD MON YYYY") Title and Subtitle Major Management Challenges and Program Risks Department of Labor Contract or... Challenges and High Risks (GAO-01-159SP), in November 2000. This 2001 Performance and Accountability Series contains separate reports on 21 agencies

Major Management Challenges and Program Risks: Small Business Administration

DTIC Science & Technology

2001-01-01

2001 Major Management Challenges and Program Risks Small Business AdministrationGAO-01-260 Form SF298 Citation Data Report Date ("DD MON YYYY...34) 00JAN2001 Report Type N/A Dates Covered (from... to) ("DD MON YYYY") Title and Subtitle Major Management Challenges and Program Risks Small Business ...Administration (SBA) as it seeks to aid, counsel, assist, and protect the interests of the nations small businesses and help businesses and families

Comprehensive Occupational Data Analysis Programs 80 (CODAP80) User’s Manual.

DTIC Science & Technology

1984-01-01

8217 -____ ____ ___ - -- -- -~--- - PA"m: 84/006a 5, -(,0 i 4. TH IkdmS. lbne ISCOMlPREHENS IVE OCCUPATIONAL DATA ANALYSIS PROGRAMS 80 (CODAP80) JAUARY 1984 User s Manua 7. Auw...AD-A144 125 COMPEHIENSIVE OCCUPATIONAL DATA ANALYSIS PROGRAMS 80 ’i (CODAP8OI USES MANUAtfUD NAVY OCCUPATIONAL DEVELOPMENT AND ANALYSIS CENTER...e COMPREVENSIVE OCCUPATIONAL DATA ANALYSIS PROGRAMS 80 (CODAP80) JANUARY 1984Uer s Manual 7. Author(s) L. pt, t wis ONapetion ft.p No. N/A 9

Experimentally determined rock-fluid interactions applicable to a natural hot dry rock geothermal system

DOE Office of Scientific and Technical Information (OSTI.GOV)

Charles, R.W.; Holley, C.E. Jr.; Tester, J.W.

1980-02-01

The Los Alamos Scientific Laboratory is pursuing laboratory and field experiments in the development of the Hot Dry Rock concept of geothermal energy. The field program consists of experiments in a hydraulically fractured region of low permeability in which hot rock is intercepted by two wellbores. These experiments are designed to test reservoir engineering parameters such as: heat extraction rates, water loss rates, flow characteristics including impedance and buoyancy, seismic activity and fluid chemistry. Laboratory experiments have been designed to provide information on the mineral reactivity which may be encountered in the field program. Two experimental circulation systems have beenmore » built to study the rates of dissolution and alteration in dynamic flow. Solubility studies have been done in agitated systems. To date, pure minerals, samples of the granodiorite from the actual reservoir and Tijeras Canyon granite have been reacted with distilled water and various solutions of NaCl, NaOH, and Na/sub 2/CO/sub 3/. The results of these experimental systems are compared to observations made in field experiments done in a hot dry rock reservoir at a depth of approximately 3 km with initial rock temperatures of 150 to 200/sup 0/C.« less

Simulating Operation of a Complex Sensor Network

NASA Technical Reports Server (NTRS)

Jennings, Esther; Clare, Loren; Woo, Simon

2008-01-01

Simulation Tool for ASCTA Microsensor Network Architecture (STAMiNA) ["ASCTA" denotes the Advanced Sensors Collaborative Technology Alliance.] is a computer program for evaluating conceptual sensor networks deployed over terrain to provide military situational awareness. This or a similar program is needed because of the complexity of interactions among such diverse phenomena as sensing and communication portions of a network, deployment of sensor nodes, effects of terrain, data-fusion algorithms, and threat characteristics. STAMiNA is built upon a commercial network-simulator engine, with extensions to include both sensing and communication models in a discrete-event simulation environment. Users can define (1) a mission environment, including terrain features; (2) objects to be sensed; (3) placements and modalities of sensors, abilities of sensors to sense objects of various types, and sensor false alarm rates; (4) trajectories of threatening objects; (5) means of dissemination and fusion of data; and (6) various network configurations. By use of STAMiNA, one can simulate detection of targets through sensing, dissemination of information by various wireless communication subsystems under various scenarios, and fusion of information, incorporating such metrics as target-detection probabilities, false-alarm rates, and communication loads, and capturing effects of terrain and threat.

Simulation and Preliminary Design of a Cold Stream Experiment on Omega EP

NASA Astrophysics Data System (ADS)

Coffing, Shane; Angulo, Adrianna; Trantham, Matt; Malamud, Guy; Kuranz, Carolyn; Drake, R. P.

2017-10-01

Galaxies form within dark matter halos, accreting gas that may clump and eventually form stars. Infalling matter gradually increases the density of the halo, and, if cooling is insufficient, rising pressure forms a shock that slows the infalling gas, reducing star formation. However, galaxies with sufficient cooling become prolific star formers. A recent theory suggests that so called ``stream fed galaxies'' are able to acquire steady streams of cold gas via galactic ``filaments'' that penetrate the halo. The cold, dense filament flowing into a hot, less dense environment is potentially Kelvin-Helmholtz unstable. This instability may hinder the ability of the stream to deliver gas deeply enough into the halo. To study this process, we have begun preliminary design of a well-scaled laser experiment on Omega EP. We present here early simulation results and the physics involved. This work is funded by the U.S. Department of Energy, through the NNSA-DS and SC-OFES Joint Program in High-Energy-Density Laboratory Plasmas, Grant Number DE-NA0002956, and the National Laser User Facility Program, Grant Number DE-NA0002719, and through the Laboratory for Laser Energetics, University of Rochester by the NNSA/OICF under Cooperative Agreement No. DE-NA0001944.

U.S. Army’s Ground Vehicle Energy Storage R&D Programs & Goals

DTIC Science & Technology

2010-11-10

STATEMENT Approved for public release; distribution unlimited 13. SUPPLEMENTARY NOTES Briefing to ARPA-E BEEST Meeting 14. ABSTRACT NA 15...Program Collaboration & DOD Customers DOE Material Developers Battery Developers ANL USABC National Labs Universities Industrial Developers...qualification for military lead acid batteries; 6 water baths, 31 circuits, 1 thermal chamber • Electrochemical Research & Analysis Lab (EARL

Vulnerability Assessments in Support of the Climate Ready ...

EPA Pesticide Factsheets

As part of the Climate Ready Estuaries (CRE) program, the Global Change Research Program (GCRP) in the National Center for Environmental Assessment, Office of Research and Development at the U.S. Environmental Protection Agency has prepared this draft report exploring a new methodology for climate change vulnerability assessments using San Francisco Bay’s salt marsh and mudflat ecosystems as a demonstration. N/A

Saad Naakih Bee'enootiilji Na'alkaa: Restructuring the Teaching of Language and Literacy in a Navajo Community School.

ERIC Educational Resources Information Center

Dick, Galena Sells; And Others

1994-01-01

Describes the 10-year development of the Rough Rock English-Navajo Language Arts Program (RRENLAP) to improve the teaching of language, literacy, and biliteracy. Discusses collaboration between Rough Rock and the Hawaii-based Kamehameha Early Education Program, key RRENLAP instructional features, and the role of bilingual teachers in the struggle…

Chemical interactions and thermodynamic studies in aluminum alloy/molten salt systems

NASA Astrophysics Data System (ADS)

Narayanan, Ramesh

The recycling of aluminum and aluminum alloys such as Used Beverage Container (UBC) is done under a cover of molten salt flux based on (NaCl-KCl+fluorides). The reactions of aluminum alloys with molten salt fluxes have been investigated. Thermodynamic calculations are performed in the alloy/salt flux systems which allow quantitative predictions of the equilibrium compositions. There is preferential reaction of Mg in Al-Mg alloy with molten salt fluxes, especially those containing fluorides like NaF. An exchange reaction between Al-Mg alloy and molten salt flux has been demonstrated. Mg from the Al-Mg alloy transfers into the salt flux while Na from the salt flux transfers into the metal. Thermodynamic calculations indicated that the amount of Na in metal increases as the Mg content in alloy and/or NaF content in the reacting flux increases. This is an important point because small amounts of Na have a detrimental effect on the mechanical properties of the Al-Mg alloy. The reactions of Al alloys with molten salt fluxes result in the formation of bluish purple colored "streamers". It was established that the streamer is liquid alkali metal (Na and K in the case of NaCl-KCl-NaF systems) dissipating into the melt. The melts in which such streamers were observed are identified. The metal losses occurring due to reactions have been quantified, both by thermodynamic calculations and experimentally. A computer program has been developed to calculate ternary phase diagrams in molten salt systems from the constituting binary phase diagrams, based on a regular solution model. The extent of deviation of the binary systems from regular solution has been quantified. The systems investigated in which good agreement was found between the calculated and experimental phase diagrams included NaF-KF-LiF, NaCl-NaF-NaI and KNOsb3-TINOsb3-LiNOsb3. Furthermore, an insight has been provided on the interrelationship between the regular solution parameters and the topology of the phase diagram. The isotherms are flat (i.e. no skewness) when the regular solution parameters are zero. When the regular solution parameters are non-zero, the isotherms are skewed. A regular solution model is not adequate to accurately model the molten salt systems used in recycling like NaCl-KCl-LiF and NaCl-KCl-NaF.

Structural, optoelectronic, and thermoelectric properties of AZn13 (A=Na, K, Ca, Sr, Ba) compounds

NASA Astrophysics Data System (ADS)

Basit, Abdul; Murtaza, G.; Mahmood, Asif; Yar, Abdullah; Muhammad, S.

2016-08-01

We report the structural, electronic, optical, and thermoelectric properties of the five cubic alkali-earth transition-metals AZn13 (A-Na, K, Ca, Sr, Ba) using density functional theory. Structural properties, electronic structures and optical behaviors are calculated explicitly via highly accurate contemporary full potential-linearized augmented plane wave (FP-LAPW) method. The investigated ground state data of these materials is quite close to the experimental information. The modified Becke-Johnson (mBJ) predicts the intermetallic nature of AZn13 (A-Na, K, Ca, Sr, Ba) materials. The complex dielectric function of these intermetallic compounds has been calculated and the observed noticeable peaks are examined through mBJ. With the help of complex dielectric function, the other important optical parameters like reflectivities, conductivities and refractive indices of AZn13 (A-Na, K, Ca, Sr, Ba) have been calculated as a function of energy. The optical response suggests that AZn13 (A-Na, K, Ca, Sr, Ba) compounds can be used for the optoelectronic devices. Further, the thermoelectric properties have been calculated through BoltzTraP program, the calculated values for different thermoelectric parameters recommend that these AZn13 (A-Na, K, Ca, Sr, Ba) materials are the suitable candidates for thermoelectric applications.

MATLAB implementation of a dynamic clamp with bandwidth >125 KHz capable of generating INa at 37°C

PubMed Central

Clausen, Chris; Valiunas, Virginijus; Brink, Peter R.; Cohen, Ira S.

2012-01-01

We describe the construction of a dynamic clamp with bandwidth >125 KHz that utilizes a high performance, yet low cost, standard home/office PC interfaced with a high-speed (16 bit) data acquisition module. High bandwidth is achieved by exploiting recently available software advances (code-generation technology, optimized real-time kernel). Dynamic-clamp programs are constructed using Simulink, a visual programming language. Blocks for computation of membrane currents are written in the high-level matlab language; no programming in C is required. The instrument can be used in single- or dual-cell configurations, with the capability to modify programs while experiments are in progress. We describe an algorithm for computing the fast transient Na+ current (INa) in real time, and test its accuracy and stability using rate constants appropriate for 37°C. We then construct a program capable of supplying three currents to a cell preparation: INa, the hyperpolarizing-activated inward pacemaker current (If), and an inward-rectifier K+ current (IK1). The program corrects for the IR drop due to electrode current flow, and also records all voltages and currents. We tested this program on dual patch-clamped HEK293 cells where the dynamic clamp controls a current-clamp amplifier and a voltage-clamp amplifier controls membrane potential, and current-clamped HEK293 cells where the dynamic clamp produces spontaneous pacing behavior exhibiting Na+ spikes in otherwise passive cells. PMID:23224681

CSUNSat-1 CubeSat – ELaNa XVII

NASA Image and Video Library

2017-04-04

The primary mission of CSUNSat1 is to space test an innovative low temperature capable energy storage system developed by the Jet Propulsion Laboratory, raising its TRL level to 7 from 4 to 5. The success of this energy storage system will enable future missions, especially those in deep space to do more science while requiring less energy, mass and volume. This CubeSat was designed, built, programmed, and tested by a team of over 70 engineering and computer science students at CSUN.  The primary source of funding for CSUNSat1 comes from NASA’s Smallest Technology Partnership program. Launched by NASA’s CubeSat Launch Initiative on the NET April 18, 2017 ELaNa XVII mission on the seventh Orbital-ATK Cygnus Commercial Resupply Services (OA-7) to the International Space Station and deployed on tbd.

An Analysis of the INGRES Database Management System Applications Program Development Tools and Programming Environment

DTIC Science & Technology

1986-12-01

Position cursor over the naBe of a report, then use the appropriate enu iteffl to perforn an operation on that report. Naae Owner RBF? Last changed...LANGUAGE- INDEPENDENT, PORTABLE FILE ACCESS SY STEM A MODEL FOR AUTOMATIC FILE AND PROGRAM DESIGN IN BUSINE SS APPLICATION SYSTEM GENERALLY APPLICABLE...Article Description Year: 1988 Title: FLASH : A LANGUAGE- INDEPENDENT, PORTABLE FILE ACCESS SY STEM Authors: ALLCHIN.J.E., KaLER.A.H., WIEDERHOL.D.G

Selective, Embedded, Just-In-Time Specialization (SEJITS): Portable Parallel Performance from Sequential, Productive, Embedded Domain-Specific Languages

DTIC Science & Technology

2012-12-01

identity operation SIMD Single instruction, multiple datastream parallel computing Scala A byte-compiled programming language featuring dynamic type...Specific Languages 5a. CONTRACT NUMBER FA8750-10-1-0191 5b. GRANT NUMBER N/A 5c. PROGRAM ELEMENT NUMBER 61101E 6. AUTHOR(S) Armando Fox 5d...application performance, but usually must rely on efficiency programmers who are experts in explicit parallel programming to achieve it. Since such efficiency

Emerging Tick-Borne Disease in African Vipers Caused by a Cowdria-like Organism

DTIC Science & Technology

2006-01-01

display, a currently valid OMS control number. PLEASE DO NOT RETURN YOUR FORM TO THE ABOVE AQDRESS. 1. REPORT DATE (DD-MM- YYYY) 12. REPORT TYPE I Oct... Cause ~ by a Cowdria-like Organism I II 5a. CONTRACT NUMBER N/A 5b. GRANT NUMBER N/A 5c. PROGRAM ELEMENT NUMBER 62202F 6. AUTHOR(S) I... caused by the rIckettSIa orgamsm CowdrIa rumlnantmm, currently Ehr Ichla rummantlUm. It poses an Immment treat to the Western Hemisphere, where it could

Joint Air-to-Surface Standoff Missile (JASSM)

DTIC Science & Technology

2013-12-01

LRIP Decision/Contract Award JAN 2001 JAN 2001 JAN 2002 DEC 2001 Lot II Contract Award JAN 2002 JAN 2002 JAN 2003 NOV 2002 RAA /B-52 SEP 2002 SEP 2002...SEP 2003 SEP 2003 Milestone III OCT 2003 OCT 2003 JUL 2004 APR 2004 RAA /F-16 DEC 2003 DEC 2003 DEC 2004 DEC 2004 IOC/F/A-18 E/F JUN 2009 N/A N/A N/A...Engineering and Manufacturing Development PDRR - Program Definition and Risk Reduction RAA - Required Assets Available JASSM-ER Milestones SAR Baseline Prod

Teaching Ionic Solvation Structure with a Monte Carlo Liquid Simulation Program

ERIC Educational Resources Information Center

Serrano, Agostinho; Santos, Flavia M. T.; Greca, Ileana M.

2004-01-01

The use of molecular dynamics and Monte Carlo methods has provided efficient means to stimulate the behavior of molecular liquids and solutions. A Monte Carlo simulation program is used to compute the structure of liquid water and of water as a solvent to Na(super +), Cl(super -), and Ar on a personal computer to show that it is easily feasible to…

Using ePortfolios to Assess Applied and Collaborative Learning and Academic Identity in a Summer Research Program for Community College Students

ERIC Educational Resources Information Center

Singer-Freeman, Karen; Bastone, Linda; Skrivanek, Joseph

2016-01-01

We evaluate the extent to which ePortfolios can be used to assess applied and collaborative learning and academic identity among community college students from underrepresented minority groups who participated in a summer research program. Thirty-eight students were evaluated by their research sponsor and two or three naïve faculty evaluators.…

MIT Lincoln Laboratory Annual Report 2007: Technology in Support of National Security

DTIC Science & Technology

2007-01-01

technical innovation and scientific discoveries. MISSION: TechnoLogy In SupporT of naTIonaL SecurITy 2007 Dr. Claude R. Canizares Vice president for...problems. The Lincoln Laboratory New Technology Initiatives Program is one of several internal technology innovation mechanisms. Technologies emerging...externships. LIFT2, an innovative professional learning program for science, technology , and math teachers, serves Massachusetts metro south/west region

Stainless Steel NaK-Cooled Circuit (SNaKC) Fabrication and Assembly

NASA Technical Reports Server (NTRS)

Godfroy, Thomas J.

2007-01-01

An actively pumped Stainless Steel NaK Circuit (SNaKC) has been designed and fabricated by the Early Flight Fission Test Facility (EFF-TF) team at NASA's Marshall Space Flight Center. This circuit uses the eutectic mixture of sodium and potassium (NaK) as the working fluid building upon the experience and accomplishments of the SNAP reactor program from the late 1960's The SNaKC enables valuable experience and liquid metal test capability to be gained toward the goal of designing and building an affordable surface power reactor. The basic circuit components include a simulated reactor core a NaK to gas heat exchanger, an electromagnetic (EM) liquid metal pump, a liquid metal flow meter, an expansion reservoir and a drain/fill reservoir To maintain an oxygen free environment in the presence of NaK, an argon system is utilized. A helium and nitrogen system are utilized for core, pump, and heat exchanger operation. An additional rest section is available to enable special component testing m an elevated temperature actively pumped liquid metal environment. This paper summarizes the physical build of the SNaKC the gas and pressurization systems, vacuum systems, as well as instrumentation and control methods.

Environmental, health, and safety issues of sodium-sulfur batteries for electric and hybrid vehicles. Volume 1, Cell and battery safety

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ohi, J M

1992-09-01

This report is the first of four volumes that identify and assess the environmental, health, and safety issues involved in using sodium-sulfur (Na/S) battery technology as the energy source in electric and hybrid vehicles that may affect the commercialization of Na/S batteries. This and the other reports on recycling, shipping, and vehicle safety are intended to help the Electric and Hybrid Propulsion Division of the Office of Transportation Technologies in the US Department of Energy (DOE/EHP) determine the direction of its research, development, and demonstration (RD&D) program for Na/S battery technology. The reports review the status of Na/S battery RD&Dmore » and identify potential hazards and risks that may require additional research or that may affect the design and use of Na/S batteries. This volume covers cell design and engineering as the basis of safety for Na/S batteries and describes and assesses the potential chemical, electrical, and thermal hazards and risks of Na/S cells and batteries as well as the RD&D performed, under way, or to address these hazards and risks. The report is based on a review of the literature and on discussions with experts at DOE, national laboratories and agencies, universities, and private industry. Subsequent volumes will address environmental, health, and safety issues involved in shipping cells and batteries, using batteries to propel electric vehicles, and recycling and disposing of spent batteries. The remainder of this volume is divided into two major sections on safety at the cell and battery levels. The section on Na/S cells describes major component and potential failure modes, design, life testing and failure testing, thermal cycling, and the safety status of Na/S cells. The section on batteries describes battery design, testing, and safety status. Additional EH&S information on Na/S batteries is provided in the appendices.« less

A study of photon interaction in some hormones

NASA Astrophysics Data System (ADS)

Manjunatha, H. C.

2013-05-01

The effective atomic numbers (Z eff) and electron density (N el) of some hormones such as testosterone, methandienone, estradiol and rogesterone for total and partial photon interactions have been computed in the wide energy region 1 keV-100 GeV using an accurate database of photon-interaction cross sections and the WinXCom program. The computed Z eff and N el are compared with the values generated by XMuDat program. The computer tomography (CT) numbers and kerma values relative to air are also calculated and the computed data of CT numbers in the low-energy region help in visualizing the image of the biological samples and to obtain precise accuracy in treating the inhomogenity of them in medical radiology. In view of dosimetric interest, the photon absorbed dose rates of some commonly used gamma sources (Na-21, Cs-137, Mn-52, Co-60 and Na-22) are also estimated.

Maternal High-Fat and High-Salt Diets Have Differential Programming Effects on Metabolism in Adult Male Rat Offspring.

PubMed

Segovia, Stephanie A; Vickers, Mark H; Harrison, Claudia J; Patel, Rachna; Gray, Clint; Reynolds, Clare M

2018-01-01

Maternal high-fat or high-salt diets can independently program adverse cardiometabolic outcomes in offspring. However, there is a paucity of evidence examining their effects in combination on metabolic function in adult offspring. Female Sprague Dawley rats were randomly assigned to either: control (CD; 10% kcal from fat, 1% NaCl), high-salt (SD; 10% kcal from fat, 4% NaCl), high-fat (HF; 45% kcal from fat, 1% NaCl) or high-fat and salt (HFSD; 45% kcal from fat, 4% NaCl) diets 21 days prior to mating and throughout pregnancy and lactation. Male offspring were weaned onto a standard chow diet and were culled on postnatal day 130 for plasma and tissue collection. Adipocyte histology and adipose tissue, liver, and gut gene expression were examined in adult male offspring. HF offspring had significantly greater body weight, impaired insulin sensitivity and hyperleptinemia compared to CD offspring, but these increases were blunted in HFSD offspring. HF offspring had moderate adipocyte hypertrophy and increased expression of the pre-adipocyte marker Dlk1 . There was a significant effect of maternal salt with increased hepatic expression of Dgat1 and Igfb2 . Gut expression of inflammatory ( Il1r1, Tnfα, Il6 , and Il6r ) and renin-angiotensin system ( Agtr1a, Agtr1b ) markers was significantly reduced in HFSD offspring compared to HF offspring. Therefore, salt mitigates some adverse offspring outcomes associated with a maternal HF diet, which may be mediated by altered adipose tissue morphology and gut inflammatory and renin-angiotensin regulation.

Consensus on the solubility of NaCl in water from computer simulations using the chemical potential route.

PubMed

Benavides, A L; Aragones, J L; Vega, C

2016-03-28

The solubility of NaCl in water is evaluated by using three force field models: Joung-Cheatham for NaCl dissolved in two different water models (SPC/E and TIP4P/2005) and Smith Dang NaCl model in SPC/E water. The methodology based on free-energy calculations [E. Sanz and C. Vega, J. Chem. Phys. 126, 014507 (2007)] and [J. L. Aragones et al., J. Chem. Phys. 136, 244508 (2012)] has been used, except, that all calculations for the NaCl in solution were obtained by using molecular dynamics simulations with the GROMACS package instead of homemade MC programs. We have explored new lower molalities and made longer runs to improve the accuracy of the calculations. Exploring the low molality region allowed us to obtain an analytical expression for the chemical potential of the ions in solution as a function of molality valid for a wider range of molalities, including the infinite dilute case. These new results are in better agreement with recent estimations of the solubility obtained with other methodologies. Besides, two empirical simple rules have been obtained to have a rough estimate of the solubility of a certain model, by analyzing the ionic pairs formation as a function of molality and/or by calculating the difference between the NaCl solid chemical potential and the standard chemical potential of the salt in solution.

A nutrition curriculum for families with high blood pressure.

PubMed

Farris, R P; Frank, G C; Webber, L S; Berenson, G S

1985-03-01

A nutrition curriculum for 48 students age eight-18 years with high blood pressure was implemented in Franklinton, La., as part of A Dietary/Exercise Alteration Program Trial (ADAPT), a model promoting reduced sodium (Na+) and energy intake and increased potassium (K+) intake. A teacher guide listed basic concepts, teacher and student activities, materials, behavioral outcomes, and evaluation for 12 lessons at three age levels. Games were used to present new information and increase student involvement. Taste-tests promoted attitude change regarding acceptable snacks. Decision-making and assertiveness topics facilitated independent food choices and coping with peers. Self-monitoring of intakes encouraged personal responsibility for eating behavior. Results of paired t-tests showed knowledge increased 8.7% in the spring (p less than 0.01), 4.9% in the summer (N.S.), and 7.3% in the fall (p less than 0.0001). No significant differences in increase in posttest scores by age were found. Comparisons of curriculum compliance with medication use and blood pressure change showed no relationship. A multiple regression analysis of sodium-creatinine (Na+/Cr) ratios on class attendance and posttest scores showed that children with the highest test scores had lower Na+/Cr ratios. This program increased information and skills for those motivated to change lifestyle to control obesity and blood pressure.

Parallel Algorithms for Computer Vision

DTIC Science & Technology

1990-04-01

NA86-1, Thinking Machines Corporation, Cambridge, MA, December 1986. [43] J. Little, G. Blelloch, and T. Cass. How to program the connection machine for... to program the connection machine for computer vision. In Proc. Workshop on Comp. Architecture for Pattern Analysis and Machine Intell., 1987. [92] J...In Proceedings of SPIE Conf. on Advances in Intelligent Robotics Systems, Bellingham, VA, 1987. SPIE. [91] J. Little, G. Blelloch, and T. Cass. How

Acute attenuation of fatigue after sodium bicarbonate supplementation does not manifest into greater training adaptations after 10-weeks of resistance training exercise.

PubMed

Siegler, Jason C; Marshall, Paul W M; Finn, Harrison; Cross, Rebecca; Mudie, Kurt

2018-01-01

In two concurrent studies, we aimed to a) confirm the acute effect of 0.3 g·kg-1 body weight (BW) sodium bicarbonate (NaHCO3) supplementation on central and peripheral mechanisms associated with explosive power (Study 1) and b) determine whether chronic NaHCO3 supplementation would improve the adaptive response of the neuromuscular system during a 10-week resistance training program (Study 2). Eight resistance trained participants volunteered after providing written consent. The experimental design consisted of a week of baseline testing, followed by ten weeks of training with progress measures performed in Week 5. Study 1 involved neuromuscular measurements before and after the leg extension portion of a power based training session performed in Week 1. Changes in maximal torque (MVT) and rates of torque development (RTD), along with other variables derived from femoral nerve stimulation (e.g. voluntary activation, neural recruitment) were analysed to determine the extent of fatigue under NaHCO3 or placebo conditions. Changes in these same variables, coupled with functional 1-repetition maximum leg extension strength, were measured in Study 2 from baseline (Week 0) to Week 5, and again at Week 10. In Study 1, we observed a decline after the leg extension task in both MVT (~ 30%) and rates of torque production (RTD) irrespective of acid-base status, however the decline in maximal RTD (RTDMAX) was nearly 20% less in the NaHCO3 condition when compared to placebo (mean difference of 294.8 ± 133.4 Nm·s-1 (95% CI -583.1 to -6.5 Nm, p < 0.05)). The primary finding in Study 2, however, suggests that introducing NaHCO3 repeatedly during a 10-week RT program does not confer any additional benefit to the mechanisms (and subsequent adaptive processes) related to explosive power production.

High Density Hydrogen Storage System Demonstration Using NaAlH4 Based Complex Compound Hydrides

DOE Office of Scientific and Technical Information (OSTI.GOV)

Daniel A. Mosher; Xia Tang; Ronald J. Brown

2007-07-27

This final report describes the motivations, activities and results of the hydrogen storage independent project "High Density Hydrogen Storage System Demonstration Using NaAlH4 Based Complex Compound Hydrides" performed by the United Technologies Research Center under the Department of Energy Hydrogen Program, contract # DE-FC36-02AL67610. The objectives of the project were to identify and address the key systems technologies associated with applying complex hydride materials, particularly ones which differ from those for conventional metal hydride based storage. This involved the design, fabrication and testing of two prototype systems based on the hydrogen storage material NaAlH4. Safety testing, catalysis studies, heat exchangermore » optimization, reaction kinetics modeling, thermochemical finite element analysis, powder densification development and material neutralization were elements included in the effort.« less

ELaNa - Educational Launch of Nanosatellite Enhance Education Through Space Flight

NASA Technical Reports Server (NTRS)

Skrobot, Garrett Lee

2011-01-01

One of NASA's missions is to attract and retain students in the science, technology, engineering and mathematics (STEM) disciplines. Creating missions or programs to achieve this important goal helps strengthen NASA and the nation's future work force as well as engage and inspire Americans and the rest of the world. During the last three years, in an attempt to revitalize educational space flight, NASA generated a new and exciting initiative. This initiative, NASA's Educational Launch of Nanosatellite (ELaNa), is now fully operational and producing exciting results. Nanosatellites are small secondary satellite payloads called CubeSats. One of the challenges that the CubeSat community faced over the past few years was the lack of rides into space. Students were building CubeSats but they just sat on the shelf until an opportunity arose. In some cases, these opportunities never developed and so the CubeSat never made it to orbit. The ELaNa initiative is changing this by providing sustainable launch opportunities for educational CubeSats. Across America, these CubeSats are currently being built by students in high school all the way through graduate school. Now students know that if they build their CubeSat, submit their proposal and are selected for an ELaNa mission, they will have the opportunity to fly their satellite. ELaNa missions are the first educational cargo to be carried on expendable launch vehicles (ELY) for NASA's Launch Services Program (LSP). The first ELaNa CubeSats were slated to begin their journey to orbit in February 2011 with NASA's Glory mission. Due to an anomaly with the launch vehicle, ELaNa II and Glory failed to reach orbit. This first ELaNa mission was comprised of three IU CubeSats built by students at Montana State University (Explorer Prime Flight 1), the University of Colorado (HERMES), and Kentucky Space, a consortium of state universities (KySat). The interface between the launch vehicle and the CubeSat, the Poly-Picosatellite Orbital Deployer (P-POD), was developed and built by students at California Polytechnic State University (Cal Poly). Integrating a P-POD on a NASA ELV was not an easy task. The creation of new processes and requirements as well as numerous reviews and approvals were necessary within NASA before the first ELaNa mission could be attached to a NASA launch vehicle (LV). One of the key objectives placed on an ELaNa mission is that the CubeSat and PPOD does not increase the baseline risk to the primary mission and launch vehicle. The ELaNa missions achieve this objective by placing a rigorous management and engineering process on both the LV and CubeSat teams. So, what is the future of ELaNa? Currently there are 16 P-POD missions manifested across four launch vehicles to support educational CubeSats selected under the NASA CubeSat Initiative. From this initiative, a rigorous selection process produced 22-student CubeSat missions that are scheduled to fly before the end of 2012. For the initiative to continue, organizations need to submit proposals to the annual CubeSat initiative call so they have the opportunity to be manifested and launched.

Brines formed by multi-salt deliquescence

DOE Office of Scientific and Technical Information (OSTI.GOV)

Carroll, S; Rard, J; Alai, M

2005-11-04

The FY05 Waste Package Environment testing program at Lawrence Livermore National Laboratory focused on determining the temperature, relative humidity, and solution compositions of brines formed due to the deliquescence of NaCl-KNO{sub 3}-NaNO{sub 3} and NaCl-KNO{sub 3}-NaNO{sub 3}-Ca(NO{sub 3}){sub 2} salt mixtures. Understanding the physical and chemical behavior of these brines is important because they define conditions under which brines may react with waste canister surfaces. Boiling point experiments show that NaCl-KNO{sub 3}-NaNO{sub 3} and NaCl-KNO{sub 3}-NaNO{sub 3}-Ca(NO{sub 3}){sub 2} salt mixtures form brines that transform to hydrous melts that do not truly 'dry out' until temperatures exceed 300 and 400more » C, respectively. Thus a conducting solution is present for these salt assemblages over the thermal history of the repository. The corresponding brines form at lower relative humidity at higher temperatures. The NaCl-KNO{sub 3}-NaNO{sub 3} salt mixture has a mutual deliquescence relative humidity (MDRH) of 25.9% at 120 C and 10.8% at 180 C. Similarly, the KNO{sub 3}-NaNO{sub 3} salt mixture has MDRH of 26.4% at 120 C and 20.0% at 150 C. The KNO{sub 3}-NaNO{sub 3} salt mixture salts also absorb some water (but do not appear to deliquesce) at 180 C and thus may also contribute to the transfer of electrons at interface between dust and the waste package surface. There is no experimental evidence to suggest that these brines will degas and form less deliquescent salt assemblages. Ammonium present in atmospheric and tunnel dust (as the chloride, nitrate, or sulfate) will readily decompose in the initial heating phase of the repository, and will affect subsequent behavior of the remaining salt mixture only through the removal of a stoichiometric equivalent of one or more anions. Although K-Na-NO{sub 3}-Cl brines form at high temperature and low relative humidity, these brines are dominated by nitrate, which is known to inhibit corrosion at lower temperature. Nitrate to chloride ratios of the NaCl-KNO{sub 3}-NaNO{sub 3} salt mixture are about NO{sub 3}:Cl = 19:1. The role of nitrate on corrosion at higher temperatures is addressed in a companion report (Dixit et al., 2005).« less

The U.S. Navy in the World (1991-2000): Context for U.S. Navy Capstone Strategies and Concepts

DTIC Science & Technology

2012-03-01

D0026420.A2/Final March 2012 CNA ANALYSIS & SOLUTIONS CNA is a not-for-profit organization whose professional staff of over 700 provides in-depth...www.dtic.mil or contact CNA Document Control and Distribution Section at 703-824-2123. Copyright © 2012 CNA This work was created in the performance of...N00014-11-D-0323 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER N/A 6. AUTHOR(S) Swartz, Peter M. Duggan, Karin 5d. PROJECT NUMBER N/A 5e. TASK

CONCEPTUAL BASIS FOR NATURAL ATTENUATION (NA) ...

EPA Pesticide Factsheets

As used in enforcement actions at hazardous waste sites by U.S. EPA, monitored natural attenuation is a remedy fully equivalent to any other remedy. The acceptance of MNA is based on three lines of evidence: historical ground water and/or soil chemistry data that demonstrates a trend of declining contaminant concentration, 2. hydrogeologic and geochemical data that demonstrate NA processes and rates, and 3. Field or microcosm studies. MNA is appropriate as remedial approach only where it can be demonstrated to achieve remedial objectives within reasonable time frame, and meets the applicable remedy selection criteria for the particular regulatory program. To inform the public.

Two-Phase Flow in High-Heat-Flux Micro-Channel Heat Sink for Refrigeration Cooling Applications. Part 2: Low Temperature Hybrid Micro-Channel/Micro-Jet Impingement Cooling

DTIC Science & Technology

2008-09-01

TWO-PHASE FLOW IN HIGH-HEAT-FLUX MICRO-CHANNEL HEAT SINK FOR REFRIGERATION COOLING APPLICATIONS (Contract No. N00014-05-1-0408) by Issam Mudawar ...Refrigeration Cooling Applications 5b. GRANT NUMBER N00014-04-1-0408 5c. PROGRAM ELEMENT NUMBER NA 6. AUTHOR(S) 5d. PROJECT NUMBER Mudawar , Issam NA...ABSTRACT OF Mudawar , Issam PAGES U U U UU 465 19b. TELEPHONE NUMBER (Include area code) 765-494-5705 Standard Form 298 (Rev. 8/98) Prescribed by ANSI Std

Solvent Extraction of Sodium Hydroxide Using Alkylphenols and Fluorinated Alcohols: Understanding the Extraction Mechanism by Equilibrium Modeling

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kang, Hyun-Ah; Engle, Nancy L.; Bonnesen Peter V.

2004-03-29

In the present work, it has been the aim to examine extraction efficiencies of nine proton-ionizable alcohols (HAs) in 1-octanol and to identify both the controlling equilibria and predominant species involved in the extraction process within a thermochemical model. Distribution ratios for sodium (DNa) extraction were measured as a function of organic-phase HA and aqueous-phase NaOH molarity at 25 °C. Extraction efficiency follows the expected order of acidity of the HAs, 4-(tert-octyl) phenol (HA 1a) and 4-noctyl- a,a-bis-(trifluoromethyl)benzyl alcohol (HA 2a) being the most efficient extractants among the compounds tested. By use of the equilibrium-modeling program SXLSQI, a model formore » the extraction of NaOH has been advanced based on an ion-pair extraction by the diluent to give organic-phase Na+OH- and corresponding free ions and cation exchange by the weak acids to form monomeric organic-phase Na+A- and corresponding free organic-phase ions.« less

Antenatal betamethasone attenuates the angiotensin-(1-7)-Mas receptor-nitric oxide axis in isolated proximal tubule cells.

PubMed

Su, Yixin; Bi, Jianli; Pulgar, Victor M; Chappell, Mark C; Rose, James C

2017-06-01

We previously reported a sex-specific effect of antenatal treatment with betamethasone (Beta) on sodium (Na + ) excretion in adult sheep whereby treated males but not females had an attenuated natriuretic response to angiotensin-(1-7) [Ang-(1-7)]. The present study determined the Na + uptake and nitric oxide (NO) response to low-dose Ang-(1-7) (1 pM) in renal proximal tubule cells (RPTC) from adult male and female sheep antenatally exposed to Beta or vehicle. Data were expressed as percentage of basal uptake or area under the curve for Na + or percentage of control for NO. Male Beta RPTC exhibited greater Na + uptake than male vehicle cells (433 ± 28 vs. 330 ± 26%; P < 0.05); however, Beta exposure had no effect on Na + uptake in the female cells (255 ± 16 vs. 255 ± 14%; P > 0.05). Ang-(1-7) significantly inhibited Na + uptake in RPTC from vehicle male (214 ± 11%) and from both vehicle (190 ± 14%) and Beta (209 ± 11%) females but failed to attenuate Na + uptake in Beta male cells. Beta exposure also abolished stimulation of NO by Ang-(1-7) in male but not female RPTC. Both the Na + and NO responses to Ang-(1-7) were blocked by Mas receptor antagonist d-Ala 7 -Ang-(1-7). We conclude that the tubular Ang-(1-7)-Mas-NO pathway is attenuated in males and not females by antenatal Beta exposure. Moreover, since primary cultures of RPTC retain both the sex and Beta-induced phenotype of the adult kidney in vivo they appear to be an appropriate cell model to examine the effects of fetal programming on Na + handling by the renal tubules. Copyright © 2017 the American Physiological Society.

Metering Self-Reported Adherence to Clinical Outcomes in Malaysian Patients With Hypertension: Applying the Stages of Change Model to Healthful Behaviors in the CORFIS Study.

PubMed

Karupaiah, Tilakavati; Wong, Kimberly; Chinna, Karuthan; Arasu, Kanimolli; Chee, Winnie Siew Swee

2015-06-01

The CORFIS (Community-Based Cardiovascular Risk Factors Intervention Strategies) program was piloted in community clinics in Malaysia to address the lack of health education in chronic disease management. The stages of change model was applied in a multicenter quasi-experimental design to evaluate adherence to advocated behaviors in CORFIS patients with hypertension. Based on submitted diet and exercise records (n = 209), adherence to sodium reduction, regular exercise, and increasing fruit and vegetable intake behaviors were quantified against weight, waist circumference (WC), systolic blood pressure (SBP), and diastolic blood pressure (DBP) changes. Patients were categorized at 6 months into nonadherent/N-A (Precontemplation, Contemplation, and Preparation), newly adherent/NA (Action) and totally adherent/TA (Maintenance) groups. Self-reported adherence records did not meet recommended targets for healthful behaviors, but clinical benefits were achieved by adherent groups as indicated by effect size (Cohen's d) comparisons. SBP reduction was associated with adherence to sodium reduction in NA (d = 0.60, p < .001) and TA (d = 0.45, p < .001) compared to N-A (d = 0.13, p > .05). Marginally increasing fruit and vegetable consumption (Δ = 0.41 servings) resulted in sizeable reductions in weight for NA (d = 0.81, p < .001) > TA (d = 0.54, p < .001) > N-A (d = 0.21, p > .05) and in WC for NA (d = 0.68, p < .00) > TA (d = 0.53, p < .001) > N-A (d = 0.52, p > .05). Exercise behavior was least successful as pedometer counting was below 10,000 steps but sizeable weight and WC reductions were largest for NA (d = 0.71 and 0.79, respectively) > TA (d = 0.60 and 0.53, respectively) > N-A (d = 0.33 and 0.35, respectively). Patients reporting a shift to positive stages of change behaviors enjoyed clinically beneficial reductions in SBP, DBP, weight, and WC. © 2014 Society for Public Health Education.

Nitrate reductase gene involvement in hexachlorobiphenyl dechlorination by Phanerochaete chrysosporium.

PubMed

De, Supriyo; Perkins, Michael; Dutta, Sisir K

2006-07-31

Polychlorobiphenyl (PCB) degradation usually occurs through reductive dechlorination under anaerobic conditions and phenolic ring cleavage under aerobic conditions. In this paper, we provide evidence of nitrate reductase (NaR) mediated dechlorination of hexachlorobiphenyl (PCB-153) in Phanerochaete chrysosporium under non-ligninolytic condition and the gene involved. The NaR enzyme and its cofactor, molybdenum (Mo), were found to mediate reductive dechlorination of PCBs even in aerobic condition. Tungsten (W), a competitive inhibitor of this enzyme, was found to suppress this dechlorination. Chlorine release assay provided further evidence of this nitrate reductase mediated dechlorination. Commercially available pure NaR enzyme from Aspergillus was used to confirm these results. Through homology search using TBLASTN program, NaR gene was identified, primers were designed and the RT-PCR product was sequenced. The NaR gene was then annotated in the P. chrysosporium genome (GenBank accession no. AY700576). This is the first report regarding the presence of nitrate reductase gene in this fungus with the explanation why this fungus can dechlorinate PCBs even in aerobic condition. These fungal inoculums are used commercially as pellets in sawdust for enhanced bioremediation of PCBs at the risk of depleting soil nitrates. Hence, the addition of nitrates to the pellets will reduce this risk as well as enhance its activity.

Use of Data to Develop a Code Blue Training Program

DTIC Science & Technology

2017-01-28

MDW/SGVU SUBJECT: Professional Presentation Approval 7 FEB 2016 1. Your paper, entitled Use of Data to Develop a Code Blue Training Program...3039 must be submitted for review and approval.) 6. TITLE OF MATERIAL TO BE PUBLISHED OR PRESENTED: Use of Data to Develop a Code Blue Training ...January 19, 2017 D N/A 29. COMMENTS ~ APPROVED 0 DISAPPROVED Approved training presentation with appropriate disclaimers based on training curriculum

Development of a Model and Computer Code to Describe Solar Grade Silicon Production Processes

NASA Technical Reports Server (NTRS)

Srivastava, R.; Gould, R. K.

1979-01-01

The program aims at developing mathematical models and computer codes based on these models, which allow prediction of the product distribution in chemical reactors for converting gaseous silicon compounds to condensed-phase silicon. The major interest is in collecting silicon as a liquid on the reactor walls and other collection surfaces. Two reactor systems are of major interest, a SiCl4/Na reactor in which Si(l) is collected on the flow tube reactor walls and a reactor in which Si(l) droplets formed by the SiCl4/Na reaction are collected by a jet impingement method. During this quarter the following tasks were accomplished: (1) particle deposition routines were added to the boundary layer code; and (2) Si droplet sizes in SiCl4/Na reactors at temperatures below the dew point of Si are being calculated.

Coal desulfurization by a microwave process. Technical progress report, February 1981-May 1981

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zavitsanos, P.D.; Golden, J.A.; Bleiler, K.W.

1981-01-01

Desulfurization experiments were carried out using the 6KW, 2450 MHz Flow Reactor System. The program has been directed toward the combination of physical separation and microwave exposure with NaOH to increase sulfur removal. The following treatment sequence has been used with good results: (1) expose 1/4 to 1 in. raw coal to microwaves; (2) crush the treated coal and separate the sample into float/sink fractions; (3) add NaOH to the float fraction and re-expose the sample to microwaves; and (4) wash, add NaOH and expose to microwaves. This procedure has produced up to 89% sulfur removal and as low asmore » 0.31 numberS/10/sup 6/ Btu. Ash analyses on these samples showed as high as 40% reduction. The calorific value was increased in almost all samples. Data on sulfur, ash and calorific values are summarized.« less

Impact of upgraded in vivo lung measurement capability on an internal dosimetry program

DOE Office of Scientific and Technical Information (OSTI.GOV)

Carbaugh, E.H.; Sula, M.J.; Aldridge, T.L.

1985-08-01

Implementation of high-purity germanium (Ge) detectors in place of sodium iodide (NaI) detectors for in vivo lung measurements of low-energy photon-emitting radionuclides resulted in significant improvement in detection capability and corresponding improvements in the monitoring of potentially exposed workers. Lung activities below those detectable with the NaI system were discovered during the first 18 months of operation. In a number of cases, these activities were estimated to represent intakes resulting in lung doses as high as 25% of the 15 rem/y United States Department of Energy Radiation Protection Standard. Evaluation of these lung activities and their associated intakes was substantiallymore » more time consuming than originally anticipated due to calibration differences between the Ge and NaI systems and to the difficulty of completing some of the follow-up investigations.« less

Providing Transthoracic Echocardiography Training for Intensive Care Unit Trainees: An Educational Improvement Initiative.

PubMed

Kuza, Catherine M; Hanifi, M Tariq; Koç, Melissa; Stopfkuchen-Evans, Matthias

2018-04-09

Transthoracic echocardiography (TTE) is important in the management of critically ill patients, yet it has not been incorporated into many residency programs' curricula. Our objective is to determine if trainees undergoing a 60-minute training session on TTE have improved knowledge, ultrasound skills, and increases the utilization of TTE during their rotation in the intensive care unit (ICU). We will also compare the results of participants with prior TTE exposure to TTE-naïve trainees. Our hypothesis is that after the training, participants' will have improved knowledge and ultrasound skills compared to before training. Our secondary hypotheses are that TTE-naïve trainees will have greater improvements in knowledge scores compared to those who have had prior TTE experience and trainees will increase their use of TTE in the ICU. Single-center, prospective trial. Brigham and Women's Hospital (academic hospital). Residents and fellows rotating through the ICU, at any level of postgraduate training. Forty-two trainees participated in the study. Statistically significant improvement after training was observed for all multiple choice questions (MCQ) and practical assessments (p < 0.001). When assessing the differences in score improvement between TTE-experienced versus TTE-naïve users, mean score improvements were notably higher for TTE-naïve participants (MCQ: 28.2 ± 11.6; echo clinical: 48.6 ± 23.4) compared to TTE-experienced users (MCQ: 18.6 ± 13.5, p = 0.01; echo clinical: 38.3 ± 30.2, p = 0.04). A short didactic presentation on TTE use may be useful in teaching ICU trainees basic TTE skills and encouraging the use of bedside TTE in the ICU. Copyright © 2018 Association of Program Directors in Surgery. Published by Elsevier Inc. All rights reserved.

Influence of NaCl on Growth, Proline, and Phosphoenolpyruvate Carboxylase Levels in Mesembryanthemum crystallinum Suspension Cultures 1

PubMed Central

Thomas, John C.; De Armond, Richard L.; Bohnert, Hans J.

1992-01-01

The facultative halophyte Mesembryanthemum crystallinum responds to salt stress by increasing the levels of phosphoenolpyruvate carboxylase (PEPCase) and other enzymes associated with Crassulacean acid metabolism. A more common response to salt stress in sensitive and tolerant species, including M. crystallinum, is the accumulation of proline. We have established M. crystallinum suspension cultures to investigate whether both these salt-induced responses occur at the cellular level. Leaf-and root-derived cultures maintain 5% of the total soluble amino acids as proline. Cell culture growth slows upon addition of 400 millimolar NaCl, and proline levels increase to 40% of the total soluble amino acids. These results suggest a functional salt-stress and response program in Mesembryanthemum cells. Suspension cultures grown with or without 400 millimolar NaCl have PEPCase levels that compare with those from roots and unstressed leaves. The predominant protein cross-reacting with an anti-PEPCase antibody corresponds to 105 kilodaltons (apparent molecular mass), whereas a second species of approximately 110 kilodaltons is present at low levels. In salt-stressed leaves, the 110 kilodalton protein is more prevalent. Levels of mRNA for both ppc1 (salt stress induced in leaves) and ppc2 (constitutive) genes in salt-treated suspensions cultures are equal to unstressed leaves, and only twice the levels found in untreated suspension cultures. Whereas cells accumulate proline in response to NaCl, PEPCase protein amounts remain similar in salt-treated and untreated cultures. The induction upon salt stress of the 110 kilodalton PEPCase protein and other Crassulacean acid metabolism enzymes in organized tissues is not observed in cell culture and may depend on tissue-dependent or photoautotrophy-dependent programs. ImagesFigure 4Figure 5 PMID:16668687

Significant volume reduction of tank waste by selective crystallization: 1994 Annual report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Herting, D.L.; Lunsford, T.R.

1994-09-27

The objective of this technology task plan is to develop and demonstrate a scaleable process of reclaim sodium nitrate (NaNO{sub 3}) from Hanford waste tanks as a clean nonradioactive salt. The purpose of the so-called Clean Salt Process is to reduce the volume of low level waste glass by as much as 70%. During the reporting period of October 1, 1993, through May 31, 1994, progress was made on four fronts -- laboratory studies, surrogate waste compositions, contracting for university research, and flowsheet development and modeling. In the laboratory, experiments with simulated waste were done to explore the effects ofmore » crystallization parameters on the size and crystal habit of product NaNO{sub 3} crystals. Data were obtained to allows prediction of decontamination factor as a function of solid/liquid separation parameters. Experiments with actual waste from tank 101-SY were done to determine the extent of contaminant occlusions in NaNO{sub 3} crystals. In preparation for defining surrogate waste compositions, single shell tanks were categorized according to the weight percent NaNO{sub 3} in each tank. A detailed process flowsheet and computer model were created using the ASPENPlus steady state process simulator. This is the same program being used by the Tank Waste Remediation System (TWRS) program for their waste pretreatment and disposal projections. Therefore, evaluations can be made of the effect of the Clean Salt Process on the low level waste volume and composition resulting from the TWRS baseline flowsheet. Calculations, using the same assumptions as used for the TWRS baseline where applicable indicate that the number of low level glass vaults would be reduced from 44 to 16 if the Clean Salt Process were incorporated into the baseline flowsheet.« less

Segmental sodium reabsorption by the renal tubule in prenatally programmed hypertension in the rat.

PubMed

Alwasel, Saleh H; Ashton, Nick

2012-02-01

Hypertension and renal dysfunction can be programmed in the rat by prenatal exposure to a low-protein (LP) diet. Expression of the renal thick ascending limb (TAL) sodium transporter NKCC2 is up-regulated, which has been predicted to result in greater sodium reabsorption. However, we have shown that LP rats excrete more not less sodium. The aim of this study was to determine whether the increased abundance of sodium:potassium:chloride (Na(+):K(+):2Cl(-)) co-transporter (NKCC2) leads to enhanced sodium uptake by the TAL. Pregnant Wistar rats were fed a control (18%) or LP (9%) diet. Amiloride (AM), bendroflumethiazide (BF), and furosemide (FUR) were administered acutely to male offspring at 4 weeks of age. Fractional excretion of sodium (FE(Na)) was significantly greater in vehicle-infused LP rats (3.0 ± 0.3%) compared with controls (1.7 ± 0.5, P < 0.01). FE(Na) by the LP proximal tubule did not differ from controls, whereas FE(Na) by the distal tubule was significantly greater (P < 0.01). These differences were abolished by the administration of AM + BF (equivalent to the outflow from the TAL) and AM + BF + FUR (equivalent to the outflow from the proximal tubule), suggesting that the increase in NKCC2 expression was not functional. However, during acute salt loading, the LP rat pressure natriuresis curve was shifted rightward, implying that raised systemic blood pressure is required to match urinary sodium excretion with dietary intake. These data suggest that renal sodium handling is impaired in the LP rat but that this is not due to increased NKCC2 expression.

Utilizing computerized entertainment education in the development of decision aids for lower literate and naïve computer users.

PubMed

Jibaja-Weiss, Maria L; Volk, Robert J

2007-01-01

Decision aids have been developed by using various delivery methods, including interactive computer programs. Such programs, however, still rely heavily on written information, health and digital literacy, and reading ease. We describe an approach to overcome these potential barriers for low-literate, underserved populations by making design considerations for poor readers and naïve computer users and by using concepts from entertainment education to engage the user and to contextualize the content for the user. The system design goals are to make the program both didactic and entertaining and the navigation and graphical user interface as simple as possible. One entertainment education strategy, the soap opera, is linked seamlessly to interactive learning modules to enhance the content of the soap opera episodes. The edutainment decision aid model (EDAM) guides developers through the design process. Although designing patient decision aids that are educational, entertaining, and targeted toward poor readers and those with limited computer skills is a complex task, it is a promising strategy for aiding this population. Entertainment education may be a highly effective approach to promoting informed decision making for patients with low health literacy.

Moral distress in rehabilitation professionals: results from a hospital ethics survey.

PubMed

Mukherjee, Debjani; Brashler, Rebecca; Savage, Teresa A; Kirschner, Kristi L

2009-05-01

Moral distress in the rehabilitation setting was examined in a follow-up survey. The survey had 3 goals: (1) to systematically and anonymously gather data about the ethical issues that employees struggle with in their daily work; (2) to raise the visibility of the hospital-based ethics program and resources available to employees; and (3) to prioritize and focus the direction of the program's educational seminars, quality improvement projects, and ethics consultation. Online survey of employees. Urban rehabilitation system of care. The survey was open to all employees; 207 completed the survey. N/A MAIN OUTCOME MEASUREMENTS: N/A CONCLUSIONS: Three broad categories of moral distress were identified: institutional ethics, professional practice, and clinical decision-making. Institutional ethics issues related to the health care environment, such as health care reimbursement pressures and corporate culture. Professional practice issues involved codes of behavior and concepts of professionalism, including patient confidentiality/privacy. Clinical decision-making included such practical dilemmas as conflicts around goal-setting, discharge planning, and assessment of decision-making capacity. An anonymous survey of staff members allowed the hospital ethics program to identify sources of moral distress and prioritize strategies to address them.

78 FR 32005 - Agency Information Collection Activities; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-28

...; SF-270. Affected Public: Businesses. Respondent Universe: 7 Railroads. Frequency of Submission: On occasion. Reporting Burden: Total annual Average time per Total annual Grant program Respondent universe... Number(s): N/A. Affected Public: States. Respondent Universe: 10 States. Frequency of Submission: On...

75 FR 968 - Notice of Public Information Collections Being Reviewed by the U.S. Agency for International...

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2010-01-07

... . SUPPLEMENTARY INFORMATION: OMB No.: OMB 0412-New. Form No.: N/A. Title: Mentor-Prot[eacute]g[eacute] Program... the mentor-prot[eacute]g[eacute] agreement is meeting its milestones outlined in the original...

76 FR 30243 - Minimum Security Devices and Procedures

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-24

... DEPARTMENT OF THE TREASURY Office of Thrift Supervision Minimum Security Devices and Procedures.... Title of Proposal: Minimum Security Devices and Procedures. OMB Number: 1550-0062. Form Number: N/A. Description: The requirement that savings associations establish a written security program is necessitated by...

Symbiotic Optimization of Behavior

DTIC Science & Technology

2015-05-01

SYMBIOTIC OPTIMIZATION OF BEHAVIOR UNIVERSITY OF WASHINGTON MAY 2015 FINAL TECHNICAL REPORT APPROVED FOR PUBLIC RELEASE; DISTRIBUTION UNLIMITED...2014 4. TITLE AND SUBTITLE SYMBIOTIC OPTIMIZATION OF BEHAVIOR 5a. CONTRACT NUMBER FA8750-12-1-0304 5b. GRANT NUMBER N/A 5c. PROGRAM ELEMENT

Rapid quantification of iron content in fish sauce and soy sauce: a promising tool for monitoring fortification programs.

PubMed

Laillou, Arnaud; Icard-Vernière, Christèle; Rochette, Isabelle; Picq, Christian; Berger, Jacques; Sambath, Pol; Mouquet-Rivier, Claire

2013-06-01

In a number of Southeast Asian countries and China, fish sauce and soy sauce produced at the industrial level are fortified with iron. Unfortunately, the food producers and regulatory agencies implementing fortification programs do not always have the capacity to monitor the programs on an ongoing basis. To assess a new portable device for the quantitative measurement of iron content of fortified sauces that could be used to control fortification levels. The linearity, detection limits, and inter- and intraassay variability of this device were assessed on fish sauce and soy sauce fortified with ferrous sulfate, ferrous fumarate, and sodium iron ethylenediaminetetraacetate (NaFeEDTA); the accuracy of the results was determined by comparing them with the results obtained by atomic absorption spectrophotometry. Measurements required a minimum incubation time of 1 hour for iron sulfate or iron fumarate and 24 hours for NaFeEDTA. Linearity of the results ranged from 2 to 10 mg iron/L for ferrous sulfate or ferrous fumarate and from 1 to 10 mg iron/L for NaFeEDTA, implying the need for proper dilution, as the iron contents of fortified sauce are usually in the range of 150 to 1,000 mg/L. Depending on incubation time, iron compounds, and sauces, the coefficient of variation (CV) of intraassay precision was between 1.5% and 7.6% and the CV of interassay precision was between 2.9% and 7.4%. Comparison with results from atomic absorption spectrophotometry showed high agreement between both methods, with R = 0.926 and R = 0.935 for incubation times of 1 hour and 24 hours, respectively. The Bland-Altman plots showed limits of agreement between the two methods of +/- 70 mg/L in the range of fortification levels tested (100 to 500 mg/L). CONCLUSIONS; This device offers a viable method for field monitoring of iron fortification of soy and fish sauces after incubation times of 1 hour for ferrous sulfate or ferrous fumarate and 24 hours for NaFeEDTA.

Design of Experiments Relevant to Accreting Stream-Disk Impact in Interacting Binaries

NASA Astrophysics Data System (ADS)

Krauland, Christine; Drake, R. P.; Kuranz, C. C.; Grosskopf, M. J.; Young, R.; Plewa, T.

2010-05-01

In many Cataclysmic Binary systems, mass transfer via Roche lobe overflow onto an accretion disk occurs. This produces a hot spot from the heating created by the supersonic impact of the infalling flow with the rotating accretion disk, which can produce a radiative reverse shock in the infalling flow. This collision region has many ambiguities as a radiation hydrodynamic system. Depending upon conditions, it has been argued (Armitgae & Livio, ApJ 493, 898) that the shocked region may be optically thin, thick, or intermediate, which has the potential to significantly alter its structure and emissions. Laboratory experiments have yet to produce colliding flows that create a radiative reverse shock or to produce obliquely incident colliding flows, both of which are aspects of these Binary systems. We have undertaken the design of such an experiment, aimed at the Omega-60 laser facility. The design elements include the production of postshock flows within a dense material layer or ejecta flows by release of material from a shocked layer. Obtaining a radiative reverse shock in the laboratory requires producing a sufficiently fast flow (> 100 km/s) within a material whose opacity is large enough to produce energetically significant emission from experimentally achievable layers. In this poster we will discuss the astrophysical context, the experimental design work we have done, and the challenges of implementing and diagnosing an actual experiment. This work is funded by the NNSA-DS and SC-OFES Joint Program in High-Energy-Density Laboratory Plasmas, by the National Laser User Facility Program in NNSA-DS and by the Predictive Sciences Academic Alliances Program in NNSA-ASC. The corresponding grant numbers are DE-FG52-09NA29548, DE-FG52-09NA29034, and DE-FC52-08NA28616.

Physical and chemical properties and adsorption type of activated carbon prepared from plum kernels by NaOH activation.

PubMed

Tseng, Ru-Ling

2007-08-25

Activated carbon was prepared from plum kernels by NaOH activation at six different NaOH/char ratios. The physical properties including the BET surface area, the total pore volume, the micropore ratio, the pore diameter, the burn-off, and the scanning electron microscope (SEM) observation as well as the chemical properties, namely elemental analysis and temperature programmed desorption (TPD), were measured. The results revealed a two-stage activation process: stage 1 activated carbons were obtained at NaOH/char ratios of 0-1, surface pyrolysis being the main reaction; stage 2 activated carbons were obtained at NaOH/char ratios of 2-4, etching and swelling being the main reactions. The physical properties of stage 2 activated carbons were similar, and specific area was from 1478 to 1887m(2)g(-1). The results of reaction mechanism of NaOH activation revealed that it was apparently because of the loss ratio of elements C, H, and O in the activated carbon, and the variations in the surface functional groups and the physical properties. The adsorption of the above activated carbons on phenol and three kinds of dyes (MB, BB1, and AB74) were used for an isotherm equilibrium adsorption study. The data fitted the Langmuir isotherm equation. Various kinds of adsorbents showed different adsorption types; separation factor (R(L)) was used to determine the level of favorability of the adsorption type. In this work, activated carbons prepared by NaOH activation were evaluated in terms of their physical properties, chemical properties, and adsorption type; and activated carbon PKN2 was found to have most application potential.

DOE Biomass Power Program: Strategic Plan 1996-2015

DTIC Science & Technology

1996-12-01

C P L A N 1 9 9 6 - 2 0 1 5 Report Documentation Page Form ApprovedOMB No. 0704-0188 Public reporting burden for the collection of...Operations and Reports , 1215 Jefferson Davis Highway, Suite 1204, Arlington VA 22202-4302. Respondents should be aware that notwithstanding any other...valid OMB control number. 1. REPORT DATE 1996 2. REPORT TYPE N/A 3. DATES COVERED - 4. TITLE AND SUBTITLE DOE Biomass Power Program 5a

An Analysis of Program Managers as Total Life Cycle Systems Managers

DTIC Science & Technology

2017-09-01

S) AND ADDRESS(ES) N/A 10. SPONSORING / MONITORING AGENCY REPORT NUMBER 11. SUPPLEMENTARY NOTES The views expressed in this thesis are those of...Total Life Cycle Systems Management (TLCSM) is a term used in Army Regulation ( AR ) 70-1 to describe the responsibility of the Army Program Manager (PM...away from the PM. However, other Army guidance challenges AR 70-1 when transitioning to the Operations and Support phase of the acquisition life

Computer program for determination of concentrations of trace elements in components of water systems by nondestructive activation analysis (in German)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Slavic, I.; Draskovic, R.; Tasovac, T.

1973-03-01

A computer program for the determination of trace elements in components of the water systems bed material, suspended material, dissolved substances, plankton, algae) by nondestructive activation analysis was developed. Results of the determination of Cr, Sb, Sc, Fe, Co, Na, and La concentrations in suspended materials from the Danube river, obtained by interpretation of data with a CDC- 3600 computer (64 k words), are presented. (auth)

Semiannual Report to Congress on the Effectiveness of the Civil Aviation Security Program.

DTIC Science & Technology

1983-10-21

Aviation Security Program -s fro January 1 -June 30, 1983 c> CD C_3 LU DTIC ELECTE NOV 1 8 1983 D <sS^ B Washington, O.C. 20691 October...Effectiveness of the Civil Aviation Security Program 7. A-.W.) Aviation Security Division V. P»tf»m..»» 0>|fi •« Nam» «n4 Aa^rai» DOT/Federal...Aviation Administration Office of Civil Aviation Security 800 Independence Avenue, SW. Washington, P.C. 20591 1. ••€•*.»•<•’• Caiala*. Na. S.

n/a

NASA Image and Video Library

1953-08-20

The first Redstone was fired at Cape Canaveral, Florida on August 20, 1953. Redstone was the first major rocket development program for United States by the Peenemuende group led by Dr. Wernher von Braun. The Redstone launch photographed here, from November 17, 1954, was the fifth launch of a Redstone rocket.

IRIS Toxicological Review of Ethylene Glycol Mono Butyl ...

EPA Pesticide Factsheets

EPA has finalized the Toxicological Review of Ethylene Glycol Mono Butyl Ether: in support of the Integrated Risk Information System (IRIS). Now final, this assessment may be used by EPA’s program and regional offices to inform decisions to protect human health. N/A

Channel doping concentration and cell program state dependence on random telegraph noise spatial and statistical distribution in 30 nm NAND flash memory

NASA Astrophysics Data System (ADS)

Tomita, Toshihiro; Miyaji, Kousuke

2015-04-01

The dependence of spatial and statistical distribution of random telegraph noise (RTN) in a 30 nm NAND flash memory on channel doping concentration NA and cell program state Vth is comprehensively investigated using three-dimensional Monte Carlo device simulation considering random dopant fluctuation (RDF). It is found that single trap RTN amplitude ΔVth is larger at the center of the channel region in the NAND flash memory, which is closer to the jellium (uniform) doping results since NA is relatively low to suppress junction leakage current. In addition, ΔVth peak at the center of the channel decreases in the higher Vth state due to the current concentration at the shallow trench isolation (STI) edges induced by the high vertical electrical field through the fringing capacitance between the channel and control gate. In such cases, ΔVth distribution slope λ cannot be determined by only considering RDF and single trap.

Space nuclear system volume accumulator development (SNAP program)

NASA Technical Reports Server (NTRS)

Whitaker, W. D.; Shimazaki, T. T.

1973-01-01

The engineering, design, and fabrication status of the volume accumulator units to be employed in the NaK primary and secondary coolant loops of the 5-kwe reactor thermoelectric system are described. Three identical VAU's are required - two for the primary coolant loop, and one for the secondary coolant loop. The VAU's utilize nested-formed bellows as the flexing member, are hermetically sealed, provide double containment and utilize a combination of gas pressure force and bellows spring force to obtain the desired pressure regulation of the coolant loops. All parts of the VAU, except the NaK inlet tube, are to be fabricated from Inconel 718.

Genetic Diversity of Salt Tolerance in Miscanthus

PubMed Central

Chen, Chang-Lin; van der Schoot, Hanneke; Dehghan, Shiva; Alvim Kamei, Claire L.; Schwarz, Kai-Uwe; Meyer, Heike; Visser, Richard G. F.; van der Linden, C. Gerard

2017-01-01

Miscanthus is a woody rhizomatous C4 grass that can be used as a CO2 neutral biofuel resource. It has potential to grow in marginal areas such as saline soils, avoiding competition for arable lands with food crops. This study explored genetic diversity for salt tolerance in Miscanthus and discovered mechanisms and traits that can be used to improve the yield under salt stress. Seventy genotypes of Miscanthus (including 57 M. sinensis, 5 M. sacchariflorus, and 8 hybrids) were evaluated for salt tolerance under saline (150 mM NaCl) and normal growing conditions using a hydroponic system. Analyses of shoot growth traits and ion concentrations revealed the existence of large variation for salt tolerance in the genotypes. We identified genotypes with potential for high biomass production both under control and saline conditions that may be utilized for growth under marginal, saline conditions. Several relatively salt tolerant genotypes had clearly lower Na+ concentrations and showed relatively high K+/Na+ ratios in the shoots under salt stress, indicating that a Na+ exclusion mechanism was utilized to prevent Na+ accumulation in the leaves. Other genotypes showed limited reduction in leaf expansion and growth rate under saline conditions, which may be indicative of osmotic stress tolerance. The genotypes demonstrating potentially different salt tolerance mechanisms can serve as starting material for breeding programs aimed at improving salinity tolerance of Miscanthus. PMID:28261243

First-principles study of the electronic properties and discharge profile of AgNa(VO2F2)2

NASA Astrophysics Data System (ADS)

Onoue, Masatoshi; Trimarchi, Giancarlo; Freeman, Arthur J.

2014-03-01

Implantable cardiac defibrillators (ICDs) require batteries with high capacities and high discharge rates to ensure the optimal operation of the device over several years. Ag2V4O11 has been a cathode material of choice for the ICDs owing to its high capacity and fast rate of electronic discharge. To reduce ICD size and improve ICD performance, a new cathode material would need to display a higher volumetric capacity and redox potential. Recently, the new cathode compound AgNa(VO2F2)2 (SSVOF) was synthesized and displayed favorable voltage for sodium-ion batteries. However, the discharge reaction has been unclear. In this presentation, we study the discharge reaction of SSVOF through DFT calculations. All calculations are performed within the PAW method using the GGA and GGA + U functionals. Among several possible reactions, we focus on the reaction Ag X + A --> AX + Ag, where X is Na(VO2F2)2 and A is Li or Na. In this reaction, the discharge occurs by replacing Ag with A. The calculated discharge potential for Li is 3.3 V in GGA and 2.9 V in GGA + U and that for Na is 3.1 V in GGA and 2.8 V in GGA + U . These values are consistent with the experimental ones. Supported by the DOE ER46536 Program.

Inducing the Formation of Functional Macroscopic Assemblies Through Programmed Orthogonal Supramolecular Interactions

DTIC Science & Technology

2014-05-27

closely coupled, could lead to new materials for artificial photosynthesis and organic electronics. The views, opinions and/or findings contained in...new materials for artificial photosynthesis and organic electronics. (a) Papers published in peer-reviewed journals (N/A for none) Enter List of

75 FR 43157 - Submission for OMB Review; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-23

... Office of Management and Budget (OMB) provide interested Federal agencies and the public an early..., Office of Management. Office of Innovation and Improvement Type of Review: Extension. Title: Application for the Investing in Innovation (i3) Grants Program. OMB #: 1855-0021. Form #: N/A. Frequency...

75 FR 47770 - Submission for OMB Review; Comment Request

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2010-08-09

... Oregon; electronic monitoring systems (EMS): installation, 6 hours; data downloads, 4 hours and EMS... have and use electronic monitoring to verify full retention of catch and for Pacific whiting shoreside... Fishery Monitoring and Catch Accounting Program. OMB Control Number: 0648-0563. Form Number(s): NA . Type...

The Relationship Between Cost Growth and Schedule Growth

DTIC Science & Technology

2003-01-01

Relationship between Cost Growth and Schedule Growth, 35th DoDCAS, SCEA 2002, Integrated Program Management Conference (IPMC) 2002, R. L. Coleman...currently valid OMB control number. 1. REPORT DATE 2003 2. REPORT TYPE N/A 3. DATES COVERED - 4. TITLE AND SUBTITLE The Relationship Between Cost...

Opposite extremes in ethylene/nitric oxide ratio induce cell death in suspension culture and root apices of tomato exposed to salt stress.

PubMed

Poór, P; Borbély, P; Kovács, Judit; Papp, Anita; Szepesi, Ágnes; Takács, Z; Tari, Irma

2014-12-01

The plant hormone ethylene or the gaseous signalling molecule nitric oxide (NO) may enhance salt stress tolerance by maintaining ion homeostasis, first of all K+/Na+ ratio of tissues. Ethylene and NO accumulation increased in the root apices and suspension culture cells of tomato at sublethal salt stress caused by 100 mM NaCl, however, the induction phase of programmed cell death (PCD) was different at lethal salt concentration. The production of ethylene by root apices and the accumulation of NO in the cells of suspension culture did not increase during the initiation of PCD after 250 mM NaCl treatment. Moreover, cells in suspension culture accumulated higher amount of reactive oxygen species which, along with NO deficiency contributed to cell death induction. The absence of ethylene in the apical root segments and the absence of NO accumulation in the cell suspension resulted in similar ion disequilibrium, namely K+/Na+ ratio of 1.41 ± 0.1 and 1.68 ± 0.3 in intact plant tissues and suspension culture cells, respectively that was not tolerated by tomato.

The coastal environment affects lead and sodium uptake by the moss Hypnum cupressiforme used as an air pollution biomonitor.

PubMed

Renaudin, Marie; Leblond, Sébastien; Meyer, Caroline; Rose, Christophe; Lequy, Emeline

2018-02-01

Several studies suggest that potential competition exists between marine cations and heavy metals for binding sites on the cell wall of mosses. This competition would impact the heavy metal concentration measured in mosses by biomonitoring programs, which may underestimate air pollution by heavy metals in a coastal environment. In the present study, we aim to identify possible mechanisms affecting lead uptake by mosses in a coastal environment, specifically, the competition between lead (Pb 2+ ) and sodium (Na + ) for binding sites in Hypnum cupressiforme (Hc). We also compared the response of continental and coastal Hc populations to Pb 2+ exposure by immersing the moss samples in artificial solutions that comprised six experimental treatments and subsequently locating and quantifying Pb 2+ and Na + using the sequential elution technique and X-ray microanalyses with a scanning electron microscope. We demonstrated that high concentrations of Pb 2+ prevented Na + from binding to the cell wall. We also examined the effect of the salt acclimation of Hc on Pb 2+ and Na + accumulation. Coastal Hc populations accumulated more Na and less Pb than continental Hc populations in all treatments. Moreover, our results showed treatment effects on the intra/extracellular distribution of Na + , as well as site. This feedback on the influence of salt stress tolerance on Pb 2+ uptake by mosses requires further study and can be investigated for other heavy metals, leading to a better use of mosses as biomonitoring tools. Copyright © 2017 Elsevier Ltd. All rights reserved.

GiNA, an Efficient and High-Throughput Software for Horticultural Phenotyping

PubMed Central

Diaz-Garcia, Luis; Covarrubias-Pazaran, Giovanny; Schlautman, Brandon; Zalapa, Juan

2016-01-01

Traditional methods for trait phenotyping have been a bottleneck for research in many crop species due to their intensive labor, high cost, complex implementation, lack of reproducibility and propensity to subjective bias. Recently, multiple high-throughput phenotyping platforms have been developed, but most of them are expensive, species-dependent, complex to use, and available only for major crops. To overcome such limitations, we present the open-source software GiNA, which is a simple and free tool for measuring horticultural traits such as shape- and color-related parameters of fruits, vegetables, and seeds. GiNA is multiplatform software available in both R and MATLAB® programming languages and uses conventional images from digital cameras with minimal requirements. It can process up to 11 different horticultural morphological traits such as length, width, two-dimensional area, volume, projected skin, surface area, RGB color, among other parameters. Different validation tests produced highly consistent results under different lighting conditions and camera setups making GiNA a very reliable platform for high-throughput phenotyping. In addition, five-fold cross validation between manually generated and GiNA measurements for length and width in cranberry fruits were 0.97 and 0.92. In addition, the same strategy yielded prediction accuracies above 0.83 for color estimates produced from images of cranberries analyzed with GiNA compared to total anthocyanin content (TAcy) of the same fruits measured with the standard methodology of the industry. Our platform provides a scalable, easy-to-use and affordable tool for massive acquisition of phenotypic data of fruits, seeds, and vegetables. PMID:27529547

GiNA, an Efficient and High-Throughput Software for Horticultural Phenotyping.

PubMed

Diaz-Garcia, Luis; Covarrubias-Pazaran, Giovanny; Schlautman, Brandon; Zalapa, Juan

2016-01-01

Traditional methods for trait phenotyping have been a bottleneck for research in many crop species due to their intensive labor, high cost, complex implementation, lack of reproducibility and propensity to subjective bias. Recently, multiple high-throughput phenotyping platforms have been developed, but most of them are expensive, species-dependent, complex to use, and available only for major crops. To overcome such limitations, we present the open-source software GiNA, which is a simple and free tool for measuring horticultural traits such as shape- and color-related parameters of fruits, vegetables, and seeds. GiNA is multiplatform software available in both R and MATLAB® programming languages and uses conventional images from digital cameras with minimal requirements. It can process up to 11 different horticultural morphological traits such as length, width, two-dimensional area, volume, projected skin, surface area, RGB color, among other parameters. Different validation tests produced highly consistent results under different lighting conditions and camera setups making GiNA a very reliable platform for high-throughput phenotyping. In addition, five-fold cross validation between manually generated and GiNA measurements for length and width in cranberry fruits were 0.97 and 0.92. In addition, the same strategy yielded prediction accuracies above 0.83 for color estimates produced from images of cranberries analyzed with GiNA compared to total anthocyanin content (TAcy) of the same fruits measured with the standard methodology of the industry. Our platform provides a scalable, easy-to-use and affordable tool for massive acquisition of phenotypic data of fruits, seeds, and vegetables.

Effects of Training Program on Recognition and Management of Depression and Suicide Risk Evaluation for Slovenian Primary-care Physicians: Follow-up Study

PubMed Central

Roškar, Saška; Podlesek, Anja; Zorko, Maja; Tavčar, Rok; Dernovšek, Mojca Zvezdana; Groleger, Urban; Mirjanič, Milan; Konec, Nuša; Janet, Evgen; Marušič, Andrej

2010-01-01

Aim To implement and evaluate an educational program for primary care physicians on recognition and treatment of depression and suicide prevention. Method The study was conducted in 3 Slovenian neighboring regions (Celje, Ravne na Koroškem, and Podravska) with similar suicide rates and other health indicators. All primary care physicians from Celje (N = 155) and Ravne na Koroškem (N = 35) were invited to participate in the educational program on depression treatment and suicide risk recognition. From January to March 2003, approximately half of them (82 out of 190; educational group) attended the program, whereas the other half (108 out of 190; control group 1) and physicians from the Podravska region (N = 164; control group 2) did not attend the program. The prescription rates of antidepressants and anxiolytics before and after the intervention were compared between the studied regions. Also, suicide rates three-years before and after the intervention were compared. Results From 2002 to 2003, there was a 2.33-fold increase in the rate of antidepressant prescriptions in the educational group (P < 0.05) and only 1.28-fold (P < 0.05) and 1.34-fold (P < 0.05) increase in control groups 1 and 2, respectively. However, the 12% decrease in suicide rate in the intervention regions was not significantly greater than the 4% decrease in the non-intervention region (P > 0.05). Conclusion Our training program was beneficial for primary care physicians’ ability to recognize and manage depression. However, there was no significant decrease in local suicide rates. PMID:20564767

Rationale for a ’Many Maps’ Phonology Machine

DTIC Science & Technology

1990-03-01

City, State, and ZIP Code) 10 SOURCE OF FUNDING NUMBERS 40005ub201/7-4-86 PROGRAM PROJECT TASK ~ WORK UNIT ELEMENT NO NO.I NO. ACCESSION NO NIA N/A NIA...seek to verify or refute. Some day, neurolinguistics may provide the decisive answer to the rationalist/empiricist debate. If so, we are confident that...linguistics program , Carnegie Mellon University. [7] Touretzky, D. S. (1989) Toward a connectionist phonology: the "many maps" ap- proach to sequencc

Summaries of Conclusions and Recommendations on Department of Defense Operations.

DTIC Science & Technology

1983-03-04

of Defense - Military (Except Procurement and Contracting) (051.0) Legislative Authodty: PL 96-226. In an attempt to reduce training costs and make...efeseAuthorization Act 1981 ( PL N6-432). S.Rept.97-146.S. RepL.96-89.3 U.S.C. 301b. GAO evaluated the Na" and Marine Corps Im~plementation program should be extended...Incentives Maer Illea ee Command, Fort Mon of Foreign Currency Transact.ons (FPCD-82-13) 28 motsi, NJ for NATO Programs Teleprocessing Serces Contracts for

Oxygen-Sodium Anticorrelation in Field RR Lyr-Type Stars

NASA Astrophysics Data System (ADS)

Andrievsky, S.; Korotin, S.; Lyashko, D.; Tsymbal, V.

2017-06-01

We have performed analysis of a large amount of the fields RR Lyr type stars spectra with the aim to derive NLTE oxygen and sodium abundances in our program stars. Fundamental parameters (Teff, log g, Vt) and metallicity were found using the method of the fitting between synthetic and observed spectra using the SME program which was developed by N. Piskunov and J. A. Valenti. As a result of this analysis anticorrelation between oxygen (O/H) and sodium (Na/H) abundances was found.

X-Ray Laser Program Report for FY 1989

DTIC Science & Technology

1990-05-24

theoretical photopumped x-ray laser program also involves the use of a neon lasant plasma. However, that is the only similarity to the Na/Ne scheme described...K-shell neon Z pinch photons of energy hv > 900 eV, photoionize inner K-shell electrons from the neutral neon, leading to Auger decay from Ne II to...is generated by electrons which are produced in the photoionization of Ne I. For example, ionization by the Ly-a line produces 150-eV photoelectrons

The Gaia-ESO Survey: Sodium and aluminium abundances in giants and dwarfs. Implications for stellar and Galactic chemical evolution

NASA Astrophysics Data System (ADS)

Smiljanic, R.; Romano, D.; Bragaglia, A.; Donati, P.; Magrini, L.; Friel, E.; Jacobson, H.; Randich, S.; Ventura, P.; Lind, K.; Bergemann, M.; Nordlander, T.; Morel, T.; Pancino, E.; Tautvaišienė, G.; Adibekyan, V.; Tosi, M.; Vallenari, A.; Gilmore, G.; Bensby, T.; François, P.; Koposov, S.; Lanzafame, A. C.; Recio-Blanco, A.; Bayo, A.; Carraro, G.; Casey, A. R.; Costado, M. T.; Franciosini, E.; Heiter, U.; Hill, V.; Hourihane, A.; Jofré, P.; Lardo, C.; de Laverny, P.; Lewis, J.; Monaco, L.; Morbidelli, L.; Sacco, G. G.; Sbordone, L.; Sousa, S. G.; Worley, C. C.; Zaggia, S.

2016-05-01

Context. Stellar evolution models predict that internal mixing should cause some sodium overabundance at the surface of red giants more massive than ~1.5-2.0 M⊙. The surface aluminium abundance should not be affected. Nevertheless, observational results disagree about the presence and/or the degree of Na and Al overabundances. In addition, Galactic chemical evolution models adopting different stellar yields lead to very different predictions for the behavior of [Na/Fe] and [Al/Fe] versus [Fe/H]. Overall, the observed trends of these abundances with metallicity are not well reproduced. Aims: We readdress both issues, using new Na and Al abundances determined within the Gaia-ESO Survey. Our aim is to obtain better observational constraints on the behavior of these elements using two samples: I) more than 600 dwarfs of the solar neighborhood and of open clusters and II) low- and intermediate-mass clump giants in six open clusters. Methods: Abundances were determined using high-resolution UVES spectra. The individual Na abundances were corrected for nonlocal thermodynamic equilibrium effects. For the Al abundances, the order of magnitude of the corrections was estimated for a few representative cases. For giants, the abundance trends with stellar mass are compared to stellar evolution models. For dwarfs, the abundance trends with metallicity and age are compared to detailed chemical evolution models. Results: Abundances of Na in stars with mass below ~2.0 M⊙, and of Al in stars below ~3.0 M⊙, seem to be unaffected by internal mixing processes. For more massive stars, the Na overabundance increases with stellar mass. This trend agrees well with predictions of stellar evolutionary models. For Al, our only cluster with giants more massive than 3.0 M⊙, NGC 6705, is Al enriched. However, this might be related to the environment where the cluster was formed. Chemical evolution models that well fit the observed [Na/Fe] vs. [Fe/H] trend in solar neighborhood dwarfs cannot simultaneously explain the run of [Al/Fe] with [Fe/H], and vice versa. The comparison with stellar ages is hampered by severe uncertainties. Indeed, reliable age estimates are available for only a half of the stars of the sample. We conclude that Al is underproduced by the models, except for stellar ages younger than about 7 Gyr. In addition, some significant source of late Na production seems to be missing in the models. Either current Na and Al yields are affected by large uncertainties, and/or some important Galactic source(s) of these elements has as yet not been taken into account. Based on observations made with the ESO/VLT, at Paranal Observatory, under program 188.B-3002 (The Gaia-ESO Public Spectroscopic Survey), and on data obtained from the ESO Archive originally observed under programs 60.A-9143, 076.B-0263 and 082.D-0726.Table 1 is only available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (ftp://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/589/A115

Impact of a Telehealth Program With Voice Recognition Technology in Patients With Chronic Heart Failure: Feasibility Study

PubMed Central

Lee, Heesun; Choi, Sae Won; Yoon, Yeonyee E; Park, Hyo Eun; Lee, Sang Eun; Lee, Seung-Pyo; Kim, Hyung-Kwan; Cho, Hyun-Jai; Choi, Su-Yeon; Lee, Hae-Young; Choi, Jonghyuk; Lee, Young-Joon; Kim, Yong-Jin; Cho, Goo-Yeong; Choi, Jinwook; Sohn, Dae-Won

2017-01-01

Background Despite the advances in the diagnosis and treatment of heart failure (HF), the current hospital-oriented framework for HF management does not appear to be sufficient to maintain the stability of HF patients in the long term. The importance of self-care management is increasingly being emphasized as a promising long-term treatment strategy for patients with chronic HF. Objective The objective of this study was to evaluate whether a new information communication technology (ICT)–based telehealth program with voice recognition technology could improve clinical or laboratory outcomes in HF patients. Methods In this prospective single-arm pilot study, we recruited 31 consecutive patients with chronic HF who were referred to our institute. An ICT-based telehealth program with voice recognition technology was developed and used by patients with HF for 12 weeks. Patients were educated on the use of this program via mobile phone, landline, or the Internet for the purpose of improving communication and data collection. Using these systems, we collected comprehensive data elements related to the risk of HF self-care management such as weight, diet, exercise, medication adherence, overall symptom change, and home blood pressure. The study endpoints were the changes observed in urine sodium concentration (uNa), Minnesota Living with Heart Failure (MLHFQ) scores, 6-min walk test, and N-terminal prohormone of brain natriuretic peptide (NT-proBNP) as surrogate markers for appropriate HF management. Results Among the 31 enrolled patients, 27 (87%) patients completed the study, and 10 (10/27, 37%) showed good adherence to ICT-based telehealth program with voice recognition technology, which was defined as the use of the program for 100 times or more during the study period. Nearly three-fourths of the patients had been hospitalized at least once because of HF before the enrollment (20/27, 74%); 14 patients had 1, 2 patients had 2, and 4 patients had 3 or more previous HF hospitalizations. In the total study population, there was no significant interval change in laboratory and functional outcome variables after 12 weeks of ICT-based telehealth program. In patients with good adherence to ICT-based telehealth program, there was a significant improvement in the mean uNa (103.1 to 78.1; P=.01) but not in those without (85.4 to 96.9; P=.49). Similarly, a marginal improvement in MLHFQ scores was only observed in patients with good adherence (27.5 to 21.4; P=.08) but not in their counterparts (19.0 to 19.7; P=.73). The mean 6-min walk distance and NT-proBNP were not significantly increased in patients regardless of their adherence. Conclusions Short-term application of ICT-based telehealth program with voice recognition technology showed the potential to improve uNa values and MLHFQ scores in HF patients, suggesting that better control of sodium intake and greater quality of life can be achieved by this program. PMID:28970189

Molten nitrate salt technology development

NASA Astrophysics Data System (ADS)

Carling, R. W.

1981-04-01

This paper presents an overview of the experimental programs underway in support of the Thermal Energy Storage for Solar Thermal Applications (TESSTA) program. The experimental programs are concentrating on molten nitrate salts which have been proposed as heat transfer and energy storage medium. The salt composition of greatest interest is drawsalt, nominally a 50-50 molar mixture of NaNO3 and KNO3 with a melting point of 220 C. Several technical uncertainties have been identified that must be resolved before nitrate based solar plants can be commercialized. Research programs at Sandia National Laboratories, universities, and industrial suppliers have been implemented to resolve these technical uncertainties. The experimental programs involve corrosion, decomposition, physical properties, and environmental cracking. Summaries of each project and how they impact central receiver applications such as the repowering/industrial retrofit and cogeneration program are presented.

75 FR 51978 - Submission for OMB Review; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-24

... date and research gaps. A competitive research program provides an opportunity for two researchers to... Estuarine Research Reserve System. OMB Control Number: 0648-0121. Form Number(s): NA. Type of Request... (CZMA; 16 U.S.C. 1461 et seq.) provides for the designation of estuarine research reserves...

Exceptional Family Member Program EFM

DTIC Science & Technology

1996-01-01

official. A legible copy of the most current Individualized Education Plan ( IEP ) must be submitted with NA\\’PERS 1754/4. SNAVPERS 1754/3 and 1754/4 must be...Center National Easter Seal Society (Mobiltv / Hearing /Sight) iEarlv Intervention) 1-800-833 3232 - * 1-800-221-6821 -- (312) 726-6200 Autism

77 FR 63423 - Proposed Collection; Comment Request for Information Collection Tools

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-16

... the Authorized Cyber Assistant Host Application form; Form 11-C, Occupational Tax and Register Return... record-keeping requirements: (1) Title: Authorized Cyber Assistant Host Application. OMB Number: 1545-2170. Form Number: N/A. Abstract: The IRS web-based software program, referred to as Cyber Assistant...

Liner Technology Program. Volume 3. Liner Development Methodology Manual

DTIC Science & Technology

1982-05-01

derivative of trimesic acid, trimenoyl-l- (2-ethyl) aziridine BNO Hydroxyl ethyl ester of carboxy-terminated polybutadiene Catocene Liquid ferrocene ...diisocyanate MAPO rris-l-(2-methyl) aziridinyl phosphine oxide I.’ lNA Methyl nedic anhydride; methyl endo-cis-cicyolo-2,2,1-5- heptene-2,3-dicarboxylic

SPARCHS: Symbiotic, Polymorphic, Automatic, Resilient, Clean-Slate, Host Security

DTIC Science & Technology

2016-03-01

SPARCHS: SYMBIOTIC , POLYMORPHIC, AUTOMATIC, RESILIENT, CLEAN-SLATE, HOST SECURITY COLUMBIA UNIVERSITY MARCH 2016 FINAL... SYMBIOTIC , POLYMORPHIC, AUTOTOMIC, RESILIENT, CLEAN-SLATE, HOST SECURITY 5a. CONTRACT NUMBER N/A 5b. GRANT NUMBER FA8750-10-2-0253 5c. PROGRAM...17 4.2.3 SYMBIOTIC EMBEDDED MACHINES

An evaluation of rain chemistry data for the John F. Kennedy Space Center, Florida and the University of Central Florida, Orlando

NASA Technical Reports Server (NTRS)

Madsen, Brooks C.; Dreschel, Thomas W.; Hinkle, C. Ross

1986-01-01

Concern over the effects of Space Shuttle launches prompted the initiation of a rather intense environmental monitoring program. The program included a precipitation monitoring network with 13 precipitation collection sites which were operated for various time periods to baseline precipitation chemistry at the John F. Kennedy Space Center (KSC). One additional site was also established as a remote background site on the Univ. of Central Florida (UCF) campus. One of the 13 sites was converted to a National Atmospheric Deposition Program (NADP) station. Collections and analyses of samples were performed using a number of methodologies during the monitoring period. An evaluation of the data for comparability and utility for acid rain research was performed using the anion/cation, measured conductivity, calculated conductivity, Cl/Na, and Mg/Na ratios. Data collected at all KSC sites between 1977 and 1981, from 1983 to 1985 at the NADP site and at UCF to 1985 are comparable and appropriate for determining acid rain trends. Examination of those comparable data showed a fairly stable pH between 1977 and 1982 and an increase of 0.2 pH units which was observed as an incremental increase between 1982 and 1983 at KSC and UCF.

File format for normalizing radiological concentration exposure rate and dose rate data for the effects of radioactive decay and weathering processes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kraus, Terrence D.

2017-04-01

This report specifies the electronic file format that was agreed upon to be used as the file format for normalized radiological data produced by the software tool developed under this TI project. The NA-84 Technology Integration (TI) Program project (SNL17-CM-635, Normalizing Radiological Data for Analysis and Integration into Models) investigators held a teleconference on December 7, 2017 to discuss the tasks to be completed under the TI program project. During this teleconference, the TI project investigators determined that the comma-separated values (CSV) file format is the most suitable file format for the normalized radiological data that will be outputted frommore » the normalizing tool developed under this TI project. The CSV file format was selected because it provides the requisite flexibility to manage different types of radiological data (i.e., activity concentration, exposure rate, dose rate) from other sources [e.g., Radiological Assessment and Monitoring System (RAMS), Aerial Measuring System (AMS), Monitoring and Sampling). The CSV file format also is suitable for the file format of the normalized radiological data because this normalized data can then be ingested by other software [e.g., RAMS, Visual Sampling Plan (VSP)] used by the NA-84’s Consequence Management Program.« less

Factors associated with the implementation of programs for drug abuse prevention in schools.

PubMed

Pereira, Ana Paula Dias; Paes, Ângela Tavares; Sanchez, Zila M

2016-08-04

To analyze if characteristics of managers, schools, and curriculum are associated with the implementation of programs for drug abuse prevention in elementary and high schools. Cross-sectional study, with random sample of 263 school managers. Data were collected between 2012 and 2013 by a program that sends forms via internet. A closed self-filling questionnaire was applied online. Statistical analysis included Chi-square tests and logistic regression models. The outcome variable was the presence of program for drug abuse prevention inserted in the daily life and educational program of the school. The explanatory variables were divided into: demographic data of the manager; characteristics of the school and of the curriculum; health education; and drug use in the school. We found that 42.5% (95%CI 36.1-49.1) of the evaluated schools had programs for drug abuse prevention. With the multiple logistic regression model, we observed that the more time the manager has worked with education, the chance of the school having a program increased at about 4.0%. Experimenting with innovative teaching techniques also increased at about six times the chance of the school developing a program for drug abuse prevention. The difficulties in the implementation of the programs were more present in state and municipal schools, when compared with private schools, due to, for instance: lack of teaching materials, lack of money, and competing demands for teaching other subjects. The implementation of programs for drug abuse prevention in the city of Sao Paulo is associated with the experience of the manager in education and with the teaching strategies of the school. Analisar se características dos dirigentes, das escolas e do currículo escolar estão associadas à implantação de programas de prevenção ao uso de drogas nas escolas do ciclo fundamental II e médio. Estudo transversal, com amostra aleatória sistemática de 263 dirigentes escolares. Os dados foram coletados nos anos de 2012 e 2013 por meio de um programa de envio de formulários pela internet. Aplicou-se questionário fechado, de autopreenchimento on-line. A análise estatística incluiu testes Qui-quadrado e modelos de regressão logística. A variável desfecho foi a presença de programa de prevenção ao uso de drogas inserido no cotidiano e no programa pedagógico da escola. As variáveis explicativas foram divididas em: dados demográficos do dirigente; características da escola e do currículo; educação em saúde; e consumo de drogas na escola. Constatou-se que 42,5% (IC95% 36,1-49,1) das escolas avaliadas possuíam programa de prevenção ao uso de drogas. Com o modelo de regressão logística múltipla, observou-se que, a cada ano de atuação do dirigente na educação, a chance de a escola ter um programa aumentava em aproximadamente 4,0%. O fato de experimentar técnicas de ensino inovadoras também aumentou em cerca de seis vezes a chance de a escola desenvolver um programa de prevenção ao uso de drogas. As dificuldades na implantação dos programas foram mais presentes nas redes estadual e municipal, quando comparadas à rede privada, destacando-se: a falta de material didático, a falta de dinheiro e as demandas concorrentes para ensino de outras disciplinas. A implantação de programas de prevenção ao uso de drogas no município de São Paulo está associada à experiência do dirigente escolar na educação e nas estratégias de ensino da escola.

The 1984 solar oscillation program of the Mt. Wilson 60-foot tower

NASA Technical Reports Server (NTRS)

Rhodes, Edward J., Jr.; Cacciani, Alessandro; Tomczyk, Steven; Ulrich, Roger K.

1986-01-01

The instrumentation, data, and preliminary results from the summer, 1984, solar oscillation observing program which was carried out using the 60-foot tower telescope of the Mt. Wilson Observatory are described. This program was carried out with a dedicated solar oscillation observing system and obtained full-disk Dopplergrams every 40 seconds for up to 11 hours per day. Between June and September, 1984, observations were obtained with a Na magneto-optical filter on 90 different days. The data analysis has progressed to the point that spherical harmonic filter functions were employed to generate a few one-dimensional power spectra from a single day's observations.

The 1984 solar oscillation program of the Mount Wilson 60-foot tower

NASA Technical Reports Server (NTRS)

Rhodes, E. J., Jr.; Cacciani, A.; Tomczyk, S.; Ulrich, R. K.

1985-01-01

The instrumentation, data, and preliminary results from the summer, 1984, solar oscillation observing program which was carried out using the 60-foot tower telescope of the Mt. Wilson Observatory are described. This program was carried out with a dedicated solar oscillation observing system and obtained full-disk Dopplergrams every 40 seconds for up to 11 hours per day. Between June and September, 1984, observations were obtained with a Na magneto-optical filter on 90 different days. The data analysis has progressed to the point that spherical harmonic filter functions were employed to generate a few one-dimensional power spectra from a single day's observations.

ELaNa - Educational Launch of Nanosatellite Providing Routine RideShare Opportunities

NASA Technical Reports Server (NTRS)

Skrobot, Garrett Lee; Coelho, Roland

2012-01-01

Since the creation of the NASA CubeSat Launch Initiative (NCSLI), the need for CubeSat rideshares has dramatically increased. After only three releases of the initiative, a total of 66 CubeSats now await launch opportunities. So, how is this challenge being resolved? NASA's Launch Services Program (LSP) has studied how to integrate PPODs on Athena, Atlas V, and Delta IV launch vehicles and has been instrumental in developing several carrier systems to support CubeSats as rideshares on NASA missions. In support of the first two ELaNa missions the Poly-Picosatellite Orbital Deployer (P-POD) was adapted for use on a Taurus XL (ELaNa I) and a Delta n (ELaNa III). Four P-PODs, which contained a total eight CubeSats, were used on these first ELaNa missions. Next up is ELaNa VI, which will launch on an Atlas V in August 2012. The four ELaNa VI CubeSats, in three P-PODs, are awaiting launch, having been integrated in the NPSCuLite. To increase rideshare capabilities, the Launch Services Program (LSP) is working to integrate P-PODs on Falcon 9 missions. The proposed Falcon 9 manifest will provide greater opportunities for the CubeSat community. For years, the standard CubeSat size was 1 U to 3U. As the desire to include more science in each cube grows, so does the standard CubeSat size. No longer is a 1 U, 1.5U, 2U or 3U CubeSat the only option available; the new CubeSat standard will include 6U and possibly even 12U. With each increase in CubeSat size, the CubeSat community is pushing the capability of the current P-POD design. Not only is the carrier system affected, but integration to the Launch Vehicle is also a concern. The development of a system to accommodate not only the 3U P-POD but also carriers for larger CubeSats is ongoing. LSP considers payloads in the lkg to 180 kg range rideshare or small/secondary payloads. As new and emerging small payloads are developed, rideshare opportunities and carrier systems need to be identified and secured. The development of a rideshare carrier system is not always cost effective. Sometimes a launch vehicle with an excellent performance record appears to be a great rideshare candidate however, after completing a feasibility study, LSP may determine that the cost of the rideshare carrier system is too great and, due to budget constraints, the development cannot go forward. With the current budget environment, one cost effective way to secure rideshare opportunities is to look for synergy with other government organizations that share the same interest.

Digital instrumentation and management of dead time: first results on a NaI well-type detector setup.

PubMed

Censier, B; Bobin, C; Bouchard, J; Aubineau-Lanièce, I

2010-01-01

The LNE-LNHB is engaged in a development program on digital instrumentation, the first step being the instrumentation of a NaI well-type detector set-up. The prototype acquisition card and its technical specifications are presented together with the first comparison with the classical NIM-based acquisition chain, for counting rates up to 100 kcps. The digital instrumentation is shown to be counting-loss free in this range. This validates the main option adopted in this project, namely the implementation of an extending dead time with live-time measurement already successfully used in the MTR2 NIM module developed at LNE-LNHB. Copyright 2010. Published by Elsevier Ltd.

Chuma na Uchizi: A Livelihood Intervention to Increase Food Security of People Living with HIV in Rural Zambia.

PubMed

Masa, Rainier; Chowa, Gina; Nyirenda, Victor

2018-01-01

The objective of this study was to evaluate the impact of Chuma na Uchizi, a livelihood intervention for people living with HIV (PLHIV) in rural Eastern Province, Zambia, on food security. The intervention included cash transfers to purchase income-generating assets, access to a savings account, and life-skills training. The study employed a non-equivalent groups design to compare intervention (n = 50) and control participants (n = 51) who were receiving outpatient care from two comparable health facilities in distinct constituencies in the same geographic area. We collected data before and after implementation of the intervention. Chuma na Uchizi improved access to food. At follow-up, the intervention group reported lower food insecurity scores compared with the control group (β = -5.65; 95% CI - 10.85 --0.45). Livelihood programs for PLHIV are practical and may be a promising approach to address food insecurity and its adverse effects.

Effective atomic numbers and electron densities of bioactive glasses for photon interaction

NASA Astrophysics Data System (ADS)

Shantappa, Anil; Hanagodimath, S. M.

2015-08-01

This work was carried out to study the nature of mass attenuation coefficient of bioactive glasses for gamma rays. Bioactive glasses are a group of synthetic silica-based bioactive materials with unique bone bonding properties. In the present study, we have calculated the effective atomic number, electron density for photon interaction of some selected bioactive glasses viz., SiO2-Na2O, SiO2-Na2O-CaO and SiO2-Na2O-P2O5 in the energy range 1 keV to 100 MeV. We have also computed the single valued effective atomic number by using XMuDat program. It is observed that variation in effective atomic number (ZPI, eff) depends also upon the weight fractions of selected bioactive glasses and range of atomic numbers of the elements. The results shown here on effective atomic number, electron density will be more useful in the medical dosimetry for the calculation of absorbed dose and dose rate.

Characterization of NaI crystal scintillators for the COHERENT collaboration

NASA Astrophysics Data System (ADS)

Erkela, Eric; Coherent Collaboration

2017-09-01

The COHERENT project aims to make a first observation of Coherent Elastic Neutrino-Nucleus Scattering (CEvNS) using a set of complimentary detector arrays located at the Spallation Neutron Source (SNS) at Oak Ridge National Laboratory. Using NaI scintillators acquired from the DHS-ASP program, we plan to construct a multi-tonne array with the capacity to detect CEvNS even in the presence of moderate background. Such an array would also have sensitivity to charged-current scattering of the SNS' pion Decay-At-Rest neutrinos with potential application to neutrinoless double-beta decay nuclear matrix element calculations. Optimization of the array design requires detailed characterization of the NaI scintillators themselves. We will show results on measurements of the light response and its linearity, as well as the energy resolution as a function of detector voltage. We also measured detector thresholds, dynamic range, and spatial and temporal variation of the detector response. This work is supported by the University of Washington Royalty Research Fund.

The Lunar Atmosphere as a Cosmic-Ray Detector

NASA Technical Reports Server (NTRS)

Wilson, T. L.

2007-01-01

The recent discovery of a tenuous sodium (Na) atmosphere on the Moon and Mercury has renewed interest in studying the lunar atmosphere since the physics involved for the two bodies is thought to be of similar nature. Na came as a surprise because it had been missed by in situ UV measurements made during the Apollo program. The new lunar observations involve the visible D1 (5896 ) and D2 (5890 ) wavelengths which are highly efficient at scattering sunlight. Although its lunar source and morphology is still not completely understood, Na is present as a collisionless exosphere - apparently in the form of a cometary-type coma with a tail that can extend hundreds of lunar radii during Leonid showers. The global shape of the atmosphere, in particular for the shaded antisolar side, has been modelled by Smyth. Since planetary atmospheres can be used as cosmic-ray (CR) spectrometers by means of their fluorescence excited by CR-induced air shower particles, the subject of the Moon s atmosphere as a CR detector will be discussed here.

National Water-Quality Assessment Program - Western Lake Michigan Drainage Basin

USGS Publications Warehouse

Setmire, J.O.

1991-01-01

A major component of the program is study-unit investigations, which comprise the princ ipal bui lding blocks of the program on which national-level asses ment activities a re based . The 60 study-unit in vestigations that make up the program are hydrologic systems that include parts of most major river bas ins and a qui fer systems. These study units cover areas of I ,200 to more than 65 ,000 square mi les and incorporate about 60 to 70 percent of the Nation's water use and popul ation e rved by public water supply. In 1991 , the Western Lake Michigan drainage basin was among the fir st 20 NA WQA study unit selected for study under the full -scale implementation plan.

The vulnerabilities in childhood and adolescence and the Brazilian public policy intervention.

PubMed

Fonseca, Franciele Fagundes; Sena, Ramony Kris R; dos Santos, Rocky Lane A; Dias, Orlene Veloso; Costa, Simone de Melo

2013-06-01

To review and discuss childhood and adolescence vulnerabilities, as well as Brazilian public policies of intervention. A narrative review was performed, considering studies published between 1990 and 2012, found in the Virtual Health Library databases (Biblioteca Virtual em Saúde - BVS). A combination of the following descriptors was used in the search strategy: "Adolescent Health", "Child Health", "Health Public Politics" and "Vulnerability". In addition, Brazilian official documents, the Statute of the Child and the Adolescent, Guardianship Council, Bolsa Família and Saúde na Escola Programs were evaluated. The results were divided into five categories of analysis: Vulnerability of Children and Adolescents in Brazil, Public Politics of Intervention to Risk Factors in Childhood and Adolescence, the Statute of the Child and the Adolescent and Guardianship Council, Bolsa Família Program and Saúde na Escola Program. The studies show that children and adolescents are vulnerable to environmental and social situations. Vulnerabilities are exhibited in daily violence within families and schools, which results in the premature entrance of children and adolescents in the work environment and/or in the drug traffic. To deal with these problems, the Brazilian Government established the Statute of the Child and the Adolescent as well as social programs. Literature exposes the risks experienced by children and adolescents in Brazil. In the other hand, a Government endeavor was identified to eliminate or minimize the suffering of those in vulnerable situations through public policies targeted to this population group.

Single-Mode, Supersonic Kelvin-Helmholtz Instability Experiment on OMEGA-EP

NASA Astrophysics Data System (ADS)

Wan, Wesley; Malamud, G.; Di Stefano, C.; Kuranz, C. C.; Drake, R.

2013-06-01

Laboratory laser experiments are able to produce and study phenomena that occur in astrophysical systems, allowing us to study mechanisms relevant to the formation, interaction, and destruction processes of stars and planets. These dynamic processes are strongly affected by hydrodynamic instabilities such as the Kelvin-Helmholtz instability, which arises when shear flow at an interface causes mixing between fluid layers. This instability is commonly observed at the boundary of cloud bands among gas planets, and can act as an atmospheric loss mechanism on planets with little to no intrinsic magnetic field. It is also observed in simulations of astrophysical systems including supernovae and wind-driven clumps. This poster discusses an upcoming experiment for the OMEGA-EP system that will produce a supersonic Kelvin-Helmholtz instability in the high-energy-density regime. This experiment will use a long laser pulse to create a sustained shock through two stratified layers separated by a seeded, single-mode perturbation. A high Mach number is believed to suppress the growth of the Kelvin-Helmholtz instability and, if sufficiently high, prevent growth entirely. We will be quantifying these effects using x-ray radiography. This work is funded by the NNSA-DS and SC-OFES Joint Program in High-Energy-Density Laboratory Plasmas, grant number DE-FG52-09NA29548, and by the National Laser User Facility Program, grant number DE-NA0000850, with additional support provided under Cooperative Agreement No. DE-FC52-08NA28302 through the Laboratory for Laser Energetics, University of Rochester.

Role of postnatal dietary sodium in prenatally programmed hypertension.

PubMed

Stewart, Tyrus; Ascani, Jeannine; Craver, Randall D; Vehaskari, V Matti

2009-09-01

In this study we examined the short- and long-term impact of early life dietary sodium (Na) on prenatally programmed hypertension. Hypertension was induced in rat offspring by a maternal low protein (LP) diet. Control and LP offspring were randomized to a high (HS), standard (SS), or low (LS) Na diet after weaning. On the SS diet, the LP pups developed hypertension by 6 weeks of age. The development of hypertension was prevented by the LS diet and exacerbated by the HS diet. Kidney nitrotyrosine content, a measure of oxidative stress, was reduced by the LS diet compared with the HS diet. The modified diets had no effect on control pups. A group of animals on the SS diet was followed up to 51 weeks of age after an early life 3-week exposure to the HS or LS diet. This brief early exposure of LP animals to the LS diet prevented the later development of hypertension and ameliorated the nephrosclerosis observed after early exposure to the HS diet. The LP offspring with early exposure to LS diet had lost their salt-sensitivity when challenged with the HS diet at the age of 43-49 weeks. No effect of early life dietary Na was observed in control animals. These results show that hypertension in this model is salt sensitive and may, in part, be mediated by salt-induced renal oxidative stress and that there may exist a developmental window which allows postnatal "reprogramming" of the hypertension.

A comparison of three strains of Holstein-Friesian cows grazed on pasture: growth, development, and puberty.

PubMed

Macdonald, K A; McNaughton, L R; Verkerk, G A; Penno, J W; Burton, L J; Berry, D P; Gore, P J S; Lancaster, J A S; Holmes, C W

2007-08-01

With the introduction of a protein milk payment system in New Zealand in 1988, there was an influx of North American (NA) Holstein-Friesian (HF) genetics into New Zealand (NZ) dairy herds, leading to an increase in the average percentage of NA genetics in NZ HF cows--from 2% in 1980 to 38% in 1999. Of interest has been the effect this change has had on farm profitability and on the management required for these animals, as well as the phenotypic changes that have occurred within the national herd under the breeding programs operated in NZ from 1970 to 1990. The objective of this study was to quantify differences in body dimensions, body weights, and puberty-related parameters among 3 strains of HF, representing animals of NZ origin representative of the genetics present in 1970 and 1990 and of NA origin with 1990s genetics. A total of 172 animals born in 1999 were compared. The strains were 1) NZ70, a strain of NZ Friesian (average 7% NA genetics) equivalent to high-genetic-merit (high Breeding Worth) cows farmed in the 1970s; 2) NZ90, a strain of HF of NZ origin (average 24% NA genetics) typical of the animals present in the 1990s; and 3) NA90, a strain of HF of NA origin (average of 91% NA genetics) typical of animals present in the 1990s. The differences in BW among all strains were significant at 6 and 12 mo of age. At 15 and 24 mo, the 2 NZ strains were significantly lighter than the NA90 animals. At 24 mo of age (i.e., prior to first calving), the NA90 strain animals (BW = 515 kg) were 22 and 34 kg heavier than the NZ90 and NZ70 strains. The body length of the NA90 strain was greater than either of the 2 NZ strains; the differences among the NA90 strain and the 2 NZ strains varied from 2 to 6 cm, with the differences generally being greater at older ages. The trend in heart girth difference among strains was similar to that observed for body length. The wither height of the NA90 animals was greater than that of the NZ strains by 1 to 7 cm, although there was no significant difference between the NA90 and NZ90 strains at birth. At puberty the NA90 heifers were 20 d older and 20 kg heavier than the NZ90 heifers, which in turn were 25 kg and 25 d older than the NZ70 heifers. The NA90 strain had a heavier mature body weight, and their older age at puberty suggested either that they mature later or that, under pastoral conditions, their growth rate is limited by their inability to consume sufficient metabolizable energy as grazed pasture, with a consequent delay in puberty. Results from this study will be useful in revising target BW in growing heifers of different germplasm.

Influence of exercise on NA- and Hsp72-induced release of IFNγ by the peritoneal suspension of macrophages and lymphocytes from genetically obese Zucker rats.

PubMed

Martín-Cordero, L; García, J J; Hinchado, M D; Bote, E; Ortega, E

2013-03-01

Regular physical exercise is recognized as a nonpharmacological therapeutic strategy in the treatment of metabolic syndrome, and has been proposed for improving obesity, diabetic status, insulin resistance, and immune response. The aim of the present study was to evaluate the effect of a regular exercise program (treadmill running, 5 days/week for 14 weeks at 35 cm/s for 35 min in the last month) on the release of the pro-inflammatory cytokine interferon gamma (IFNγ) by peritoneal cells (macrophages and lymphocytes) from obese Zucker rats (fa/fa) in response to noradrenaline (NA) and heat shock proteins of 72 kDa (Hsp72), and the possible adaptation due to training for a bout acute exercise (a single session of 25-35 min at 35 cm/s). In healthy (lean Fa/fa) and obese animals, peritoneal cells released greater concentrations of IFNγ in response to Hsp72 and lower concentrations in response to NA. The regular exercise training protocol, evaluated in the obese animals, produced a clear change in the regulation of the release of IFNγ. Peritoneal immune cells from trained animals released more IFNγ in response to NA, but there was a reduction in the release of IFNγ in response to Hsp72. In the obese animals, regular exercise caused a change in the inhibitory effect of NA (which now becomes stimulatory) and the stimulatory effect of Hsp72e (which now becomes inhibitory) in relation to the release of IFNγ. This reflects that Hsp72, induced by the prior release of NA following exercise-induced stress, plays a role in the homeostatic balance of release of IFNγ by peritoneal immune cells in obese animals during exercise.

Application of myostatin in sheep breeding programs: A review

PubMed Central

Miar, Younes; Salehi, Abdolreza; Kolbehdari, Davood; Aleyasin, Seyed Ahmad

2014-01-01

Plasma membrane H+-ATPase is a major integral membrane protein with a role in various physiological processes including abiotic stress response. To study the effect of NaCl on the expression pattern of a gene encoding the plasma membrane H+-ATPase, an experiment was carried out in a completely random design with three replications. A pair of specific primers was designed based on the sequence of the gene encoding plasma membrane H+-ATPase in Aeluropus littoralis to amplify a 259 bp fragment from the target gene by PCR. A gene encoding actin was used as reference gene to normalize the expression level of the target gene. A pair of specific primers was designed to amplify a 157 bp fragment from the actin gene by PCR. Plants were treated with different concentrations of NaCl, 0, 50, 100, 150, 200, 250, 500 and 1000 mM, for two days. Our results showed that the expression level of the plasma membrane H+-ATPase gene increased dramatically at 500 mM and then decreased with increasing concentrations of NaCl. The results also indicated that the leaves of plants, were treated with high concentrations of NaCl changed morphologically, but those grown under low concentrations of NaCl as well as the control plants did not show morphological changes in their leaves. Our results suggest a relation between morphological changes of treated plants and the expression level of the plasma membrane H+-ATPase gene in Aeluropus littoralis. PMID:27843975

78 FR 42999 - Financial Crimes Enforcement Network; Comment Request; Renewal Without Change-Administrative...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-18

...: Businesses or other for-profit and non-profit institutions. Frequency: N/A. An agency may not conduct or... made available for review as soon as possible but no earlier than five business days after the close of... international terrorism, and to implement counter-money laundering programs and compliance procedures.\\1...

17 CFR 200.18 - Director of Division of Corporation Finance.

Code of Federal Regulations, 2011 CFR

2011-04-01

... COMMISSION ORGANIZATION; CONDUCT AND ETHICS; AND INFORMATION AND REQUESTS Organization and Program Management General Organization § 200.18 Director of Division of Corporation Finance. The Director of the Division of... information statements filed pursuant to section 14(c) of the Act (15 U.S.C. 78n(a), 78n(c)). (4) The...

One-Minute Paper: Student Perception of Learning Gains

ERIC Educational Resources Information Center

Anderson, Deborah; Burns, Shari

2013-01-01

The purpose of this study was to determine students' perceptions of learning gains when using the one-minute paper. Thirty-one students from the Physical Therapy (PT) and Nurse Anesthesia (NA) programs participated in this study. Students completed the one-minute paper in three classes. An email to students clarified the "muddy" points…

"Preescolar Na Casa": Teaching Parents To Teach Children. Chapter 3.

ERIC Educational Resources Information Center

Fernandez, Ermitas

This chapter describes a school readiness program that has been implemented in rural Galicia (Spain) since 1977. Data reveal that 70 percent of Galicia's population lives in rural areas, the economy remains primarily agricultural, Galicians earn less than the national average and have the largest number of public assistance recipients, and there…

Association of Provider Scope of Practice With Successful Transition for Youth With Special Health Care Needs

DTIC Science & Technology

2011-02-01

S) AND ADDRESS(ES) 10. SPONSOR/MONITOR’S ACRONYM(S) Air Force Institute of Technology, Civilian AFIT/ ENEM Institutions Program (Medical/Dental...AFIT/ ENEM 2950 Hobson Way Wright-Patterson AFB OH 45433-7765 11. SPONSOR/MONITOR’S REPORT NUMBER(S) N/A Distribution Statement A

Non-Linear Stability of Magnetically Focused Particle Beams

DTIC Science & Technology

2012-04-01

Grande do Sul, P.O.Box 15051,91501-970 Porto Alegre, RS, Brasil N/A 9. SPONSORING / MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10. SPONSOR...Grande do Sul, Brasil www.if.ufrgs.br/~rizzato Grant: FA9550-09-1-0283 Final Performance Report April/2012 • Objectives Our main program involves the

The Effectiveness of the Improved NaHPO4-SnF2-ZrSiO4-SiO2 Prophylactic Paste.

DTIC Science & Technology

1976-03-01

C-1119 Howard University -College of Dentistry Research Washington, DC 20001 DOD DISTRIBUTION STATEMENT Approved for public release; distribution...AORESS 10. PROGRAM ELEMENT. PROJECT. TASK Howard University AREA 6 WORK UNIT NUMBERS College of Dentistry Research Washington, DC 20001 1I. CONTROLLING

Studies for the Loss of Atomic and Molecular Species from Io

NASA Technical Reports Server (NTRS)

Combi, Michael R.

1997-01-01

The general objective of this project has been to advance our theoretical understanding of Io's atmosphere and how various atomic and molecular species are lost from this atmosphere and are distributed in the circumplanetary environment of Jupiter. The scientific objectives of the larger collaborative program between AER, Inc., and the University of Michigan have been to undertake theoretical modeling studies to simulate the distributions of the exospheric gases in Io's corona and extended clouds, to investigate the importance of the various physical processes that shape their relative abundances, and with these tools to analyze observations of O, S and Na obtained by four observers: M.A. McGrath of the Space Telescope Science Institute and G.E. Ballester of the University of Michigan who each have obtained Hubble Space Telescope observations of O and S near Io, F. Scherb who continues an effort to obtain 6300 A OI observations as part of the University of Wisconsin Fabry-Perot program, and N.M. Schneider of the University of Colorado who obtained an extensive set of spectral and spatial observations of the Na emission near Io in the D-lines.

A French national breast and thyroid cancer screening programme for survivors of childhood, adolescent and young adult (CAYA) cancers - DeNaCaPST programme.

PubMed

Demoor-Goldschmidt, Charlotte; Drui, Delphine; Doutriaux, Isabelle; Michel, Gérard; Auquier, Pascal; Dumas, Agnès; Berger, Claire; Bernier, Valérie; Bohrer, Sandrine; Bondiau, Pierre-Yves; Filhon, Bruno; Fresneau, Brice; Freycon, Claire; Stefan, Dinu; Helfre, Sylvie; Jackson, Angela; Kerr, Christine; Laprie, Anne; Leseur, Julie; Mahé, Marc-André; Oudot, Caroline; Pluchard, Claire; Proust, Stéphanie; Sudour-Bonnange, Hélène; Vigneron, Céline; Lassau, Nathalie; Schlumberger, Martin; Conter, Cécile Faure; de Vathaire, Florent

2017-05-12

Survival of childhood, adolescent and young adult (CAYA) cancers has increased with progress in the management of the treatments and has reached more than 80% at 5 years. Nevertheless, these survivors are at great risk of second cancers and non-malignant co-morbidities in later life. DeNaCaPST is a non-interventional study whose aim is to organize a national screening for thyroid cancer and breast cancer in survivors of CAYA cancers. It will study the compliance with international recommendations, with the aim, regarding a breast screening programme, of offering for every woman living in France, at equal risk, an equal screening. DeNaCaPST trial is coordinated by the INSERM 1018 unit in cooperation with the LEA (French Childhood Cancer Survivor Study for Leukaemia) study's coordinators, the long term follow up committee and the paediatric radiation committee of the SFCE (French Society of Childhood Cancers). A total of 35 centres spread across metropolitan France and la Reunion will participate. FCCSS (French Childhood Cancer Survivor Study), LEA and central registry will be interrogated to identify eligible patients. To participate, centers agreed to perform a complete "long-term follow-up consultations" according to good clinical practice and the guidelines of the SFCE (French Society of Children Cancers). As survival has greatly improved in childhood cancers, detection of therapy-related malignancies has become a priority even if new radiation techniques will lead to better protection for organs at risk. International guidelines have been put in place because of the evidence for increased lifetime risk of breast and thyroid cancer. DeNaCaPST is based on these international recommendations but it is important to recognize that they are based on expert consensus opinion and are supported by neither nonrandomized observational studies nor prospective randomized trials in this specific population. Over-diagnosis is a phenomenon inherent in any screening program and therefore such programs must be evaluated.

Effects of humic acid and solution chemistry on the aggregation and dispersion of carboxyl-functionalized carbon black nanoparticles

NASA Astrophysics Data System (ADS)

Hwang, G.; Gomez-Flores, A.; Choi, S.; Han, Y., , Dr; Kim, H.

2017-12-01

The influence of humic acid, ionic strength and ionic species on the aggregation and dispersion of carboxyl-functionalized carbon black nanoparticles (CB-NPs) was systemically investigated in aqueous media. The experimental conditions of stability tests were selected to the changes in the solution chemistry (0.1-10 mM NaCl and 0.01-1 mM CaCl2) and in the presence/absence of humic acid (1 and 5 mg L-1) in an aquatic environment. The CB-NPs suspension was more rapidly settled in NaCl solution than in CaCl2. Specifically, in the case of NaCl, the aggregation rate of CB-NPs increased with ionic strength. Contrary, CB-NPs dispersed in CaCl2 were insensitive to the aggregation as the ionic strength increased; that was because specific adsorption of the divalent cation Ca2+ occurred since the zeta potential of the CB-NPs is reversed to a positive charge with increasing of the ionic strength. It was confirmed that humic acid greatly influences the stability of the CB-NPs. In particular, the dispersion of CB-NPs was improved in the whole range of ionic strengths of NaCl as well as of CaCl2. To support the results, the interaction energy between CB-NPs was calculated for each condition by using the classical Derjaguin-Landau-Verwey-Overbeek (DLVO) and modified-DLVO theories. In the presence of humic acid, the improved stability of CB-NPs is attributed to the steric repulsive force.This research was supported by the Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education (NRF-2015R1D1A3A01020766), the Ministry of Education (MOE) and National Research Foundation of Korea (NRF) through the Human Resource Training Project for Regional Innovation (2015H1C1A1035930) and Korea Energy and Mineral Resources Engineering Program (KEMREP).

Effect of alkali-treatment on the characteristics of natural zeolites with different compositions.

PubMed

Ates, Ayten

2018-08-01

A series of natural zeolites with different compositions were modified by post-synthesis modification with sodium hydroxide (NaOH) solution. Natural and modified zeolites were characterized by XRD, SEM, nitrogen adsorption, FTIR, zeta potential and temperature programmed desorption of ammonia (NH 3 -TPD). The adsorption capacities of these samples were evaluated by the adsorption of manganese from aqueous solution. The treatment with NaOH led to a decrease in the surface area and microporosity of all natural zeolites as well as partly damage of the zeolite structure depending on zeolite composition. In addition, the amount of weak, medium and strong acid sites in the zeolites was changed significantly by NaOH treatment depending on zeolite composition. The NaOH treatment resulted in a four-fold improvement in adsorption capacity of natural zeolite originated from Bigadic and a twofold decrease in that of the natural zeolite originated from Manisa-Gordes. Although the improved adsorption capacity might be mainly due to modification of porosity in the zeolites and formation of hydroxysodalite, the reduced adsorption capacity of the zeolite might be mainly due to a significant deformation of the zeolite structure. The pseudo-second-order kinetic model for the adsorption of manganese on all natural and modified zeolites fits well. Copyright © 2018 Elsevier Inc. All rights reserved.

TI-59 Programs for Multiple Regression.

DTIC Science & Technology

1980-05-01

general linear hypothesis model of full rank [ Graybill , 19611 can be written as Y = x 8 + C , s-N(O,o 2I) nxl nxk kxl nxl where Y is the vector of n...a "reduced model " solution, and confidence intervals for linear functions of the coefficients can be obtained using (x’x) and a2, based on the t...O107)l UA.LLL. Library ModuIe NASTER -Puter 0NTINA Cards 1 PROGRAM DESCRIPTION (s s 2 ror the general linear hypothesis model Y - XO + C’ calculates

Institutional Context of Carbon Cycle Science Research in the U.S. and North America - A SOCCR perspective

NASA Astrophysics Data System (ADS)

Shrestha, G.; Cavallaro, N.; Ste-Marie, C.

2016-12-01

Carbon cycle science has been a research priority in the U.S. for decades. Interagency coordination interests and research needs in U.S. carbon cycle science led to the establishment of the U.S. Carbon Cycle Science Program, the North American Carbon Program (NACP), the Ocean Carbon and Biogeochemistry Program (OCB) and other intergovernmental collaboration platforms such as CarboNA, involving the U.S., Mexico and Canada. This presentation highlights some of these activities, and the historical context, the institutional frameworks and the operational mechanisms that have helped to facilitate and advance large scale collaborative research in carbon cycle in the U.S. and North America.

A survey of advancements in nucleic acid-based logic gates and computing for applications in biotechnology and biomedicine.

PubMed

Wu, Cuichen; Wan, Shuo; Hou, Weijia; Zhang, Liqin; Xu, Jiehua; Cui, Cheng; Wang, Yanyue; Hu, Jun; Tan, Weihong

2015-03-04

Nucleic acid-based logic devices were first introduced in 1994. Since then, science has seen the emergence of new logic systems for mimicking mathematical functions, diagnosing disease and even imitating biological systems. The unique features of nucleic acids, such as facile and high-throughput synthesis, Watson-Crick complementary base pairing, and predictable structures, together with the aid of programming design, have led to the widespread applications of nucleic acids (NA) for logic gate and computing in biotechnology and biomedicine. In this feature article, the development of in vitro NA logic systems will be discussed, as well as the expansion of such systems using various input molecules for potential cellular, or even in vivo, applications.

A Survey of Advancements in Nucleic Acid-based Logic Gates and Computing for Applications in Biotechnology and biomedicine

PubMed Central

Wu, Cuichen; Wan, Shuo; Hou, Weijia; Zhang, Liqin; Xu, Jiehua; Cui, Cheng; Wang, Yanyue; Hu, Jun

2015-01-01

Nucleic acid-based logic devices were first introduced in 1994. Since then, science has seen the emergence of new logic systems for mimicking mathematical functions, diagnosing disease and even imitating biological systems. The unique features of nucleic acids, such as facile and high-throughput synthesis, Watson-Crick complementary base pairing, and predictable structures, together with the aid of programming design, have led to the widespread applications of nucleic acids (NA) for logic gating and computing in biotechnology and biomedicine. In this feature article, the development of in vitro NA logic systems will be discussed, as well as the expansion of such systems using various input molecules for potential cellular, or even in vivo, applications. PMID:25597946

Capacity enhancement of aqueous borohydride fuels for hydrogen storage in liquids

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schubert, David; Neiner, Doinita; Bowden, Mark

2015-10-01

In this work we demonstrate enhanced hydrogen storage capacities through increased solubility of sodium borate product species in aqueous media achieved by adjusting the sodium (NaOH) to boron (B(OH) 3) ratio, i.e., M/B, to obtain a distribution of polyborate anions. For a 1:1 mole ratio of NaOH to B(OH) 3, M/B = 1, the ratio of the hydrolysis product formed from NaBH 4 hydrolysis, the sole borate species formed and observed by 11B NMR is sodium metaborate, NaB(OH) 4. When the ratio is 1:3 NaOH to B(OH) 3, M/B = 0.33, a mixture of borate anions is formed and observedmore » as a broad peak in the 11B NMR spectrum. The complex polyborate mixture yields a metastable solution that is difficult to crystallize. Given the enhanced solubility of the polyborate mixture formed when M/B = 0.33 it should follow that the hydrolysis of sodium octahydrotriborate, NaB 3H 8, can provide a greater storage capacity of hydrogen for fuel cell applications compared to sodium borohydride while maintaining a single phase. Accordingly, the hydrolysis of a 23 wt% NaB 3H 8 solution in water yields a solution having the same complex polyborate mixture as formed by mixing a 1:3 molar ratio of NaOH and B(OH) 3 and releases >8 eq of H 2. By optimizing the M/B ratio a complex mixture of soluble products, including B 3O 3(OH) 5 2-, B 4O 5(OH) 4 2-, B 3O 3(OH) 4-, B 5O 6(OH) 4- and B(OH) 3, can be maintained as a single liquid phase throughout the hydrogen release process. Consequently, hydrolysis of NaB 3H 8 can provide a 40% increase in H 2 storage density compared to the hydrolysis of NaBH 4 given the decreased solubility of sodium metaborate. The authors would like to thank Jim Sisco and Paul Osenar of Protonex Inc. for useful discussion regarding liquid hydrogen storage materials for portable power applications and the U.S. DoE Office of Energy Efficiency and Renewable Energy Fuel Cell Technologies Office for their continued interest in liquid hydrogen storage carriers. Pacific Northwest National Laboratory is a multi-program national laboratory operated for DOE by Battelle. The authors dedicate the work to the memory of Professor Sheldon Shore. His contributions to boron hydride chemistry set the foundation for many who have followed.« less

75 FR 968 - Notice of Public Information Collections Being Reviewed by the U.S. Agency for International...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-07

... [email protected] . SUPPLEMENTARY INFORMATION: OMB No.: OMB 0412-New. Form No.: N/A. Title: Mentor-Prot[eacute]g[eacute] Program Annual Report. Type of Review: New. Purpose: The mentors are required to report on the progress made under each of active Mentor-Prot[eacute]g[eacute] Agreement annually throughout...

A community resource for exploring and utilizing genetic diversity in the USDA Pea Single Plant Plus Collection

USDA-ARS?s Scientific Manuscript database

Globally, pea (Pisum sativum L.) is an important temperate legume crop for food, feed, and fodder, and many breeding programs exist to develop cultivars adapted to these end uses. In order to conserve genetic diversity useful to researchers, large pea collections have been constructed by numerous na...

n/a

NASA Image and Video Library

1971-07-26

During the Apollo 15 pre-launch activity in the launch control center's firing room 1 at Kennedy Space Center, the then recently appointed NASA Administrator, Dr. James C. Fletcher (right) speaks with (Left to right) William Anders, executive secretary of the National Aeronautics and Space Council; Lt. General Sam Phillips, former Apollo Program Director; and Dr. Wernher von Braun, NASA's Deputy Associate Administrator for planning.

Multitasking and microtasking experience on the NA S Cray-2 and ACF Cray X-MP

NASA Technical Reports Server (NTRS)

Raiszadeh, Farhad

1987-01-01

The fast Fourier transform (FFT) kernel of the NAS benchmark program has been utilized to experiment with the multitasking library on the Cray-2 and Cray X-MP/48, and microtasking directives on the Cray X-MP. Some performance figures are shown, and the state of multitasking software is described.

Working Together during Noncombatant Evacuation Operations

DTIC Science & Technology

2008-04-23

5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR( S ) 5d. PROJECT NUMBER LCDR Kate M. Standifer, USN 5e...TASK NUMBER Paper Advisor (if Any): N/A 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME( S ) AND ADDRESS(ES) 8. PERFORMING...ORGANIZATION REPORT NUMBER Joint Military Operations Department Naval War College 686 Cushing Road

DREW-UCLA Breast Cancer Research and Training Program: Molecular/Cellular Pathogenesis Model

DTIC Science & Technology

2007-03-01

system in bovine renal brush- border [13] and in a bovine renal epithelial cell line NBL -1 [14]. In order to highlight the substrate difference with an... NBL -1 expresses a broad specificity Na(+)-dependent neu- tral amino acid transport system (System B0) similar to that in bovine renal brush border

AQMEII3: the EU and NA regional scale program of the Hemispheric Trasport of Air Pollution Task Force

EPA Science Inventory

The presentation builds on the work presented last year at the 14th CMAS meeting and it is applied to the work performed in the context of the AQMEII-HTAP collaboration. The analysis is conducted within the framework of the third phase of AQMEII (Air Quality Model Evaluation Inte...

Electrocatalysis of Oxygen Using Water Soluble Metal Porphyrins and Chemically Modified Porphyrin Electrodes.

DTIC Science & Technology

1983-11-01

NUMBER(’s Theodore Kuwana Grant No. ,AFOSR-78-36729 9. PERFORMING ORGANIZATION NAME AND ADDRESS 10. PROGRAM ELMENJT. PROJECT. TASK AREA &WORK UNIT...RFP. (e) sample (d) following post plasma treatment with a reducing agent, NaAlH2- (OCH2CH20CH3 )2, (Vitride, Hexcell Corp., Zeeland. itch.) at SOIC

Initial experiments to understand the interaction of stellar radiation with molecular clouds

NASA Astrophysics Data System (ADS)

Vandervort, Robert; Davis, Josh; Trantham, Matt; Klein, Sallee; Shvarts, Dov; Keiter, Paul; Drake, R. Paul

2017-10-01

Enhanced star formation triggered by local O and B type stars is an astrophysical problem of interest. O and B type stars are massive, hot stars that emit an enormous amount of radiation. This radiation acts to either compress or blow apart gas clumps in the interstellar media. For example, in the optically thick limit, when the radiation in the gas clump has a short mean free path, radiation is absorbed near the clump edge and compresses the clump. In the optically thin limit, when the mean free path is long, the radiation is absorbed throughout, acting to heat the clump. This heating explodes the gas clump. Careful selection of parameters, such as foam density or source temperature, allow the experimental platform to access different hydrodynamic regimes. 2D CRASH simulations guide our parameter selection. A stellar radiation source is mimicked by a laser-irradiated, thin, gold foil, providing a source of thermal x-rays around 100 eV. The gas clump is mimicked by low-density CRF foam. We plan to show the preliminary experimental results of this platform in the optically thick limit, from experiments scheduled in August. This work is funded by the U.S. DOE, through the NNSA-DS and SC-OFES Joint Program in HEDPLP, Grant No. DE-NA0002956, and the NLUF Program, Grant No. DE-NA0002719, and through LLE, University of Rochester by the NNSA/OICF under Cooperative Agreement No. DE-NA0001944. This work is funded by the Lawrence Livermore National Laboratory under subcontract B614207.

Experimental design to understand the interaction of stellar radiation with molecular clouds

NASA Astrophysics Data System (ADS)

Vandervort, Robert; Davis, Josh; Trantham, Matt; Klein, Sallee; Frank, Yechiel; Raicher, Erez; Fraenkel, Moshe; Shvarts, Dov; Keiter, Paul; Drake, R. Paul

2016-10-01

Enhanced star formation triggered by local O and B type stars is an astrophysical problem of interest. O and B type stars are massive, hot stars that emit an enormous amount of radiation. This radiation acts to either compress or blow apart clumps of gas in the interstellar media. For example, in the optically thick limit, when the x-ray radiation in the gas clump has a short mean free path length the x-ray radiation is absorbed near the clump edge and compresses the clump. In the optically thin limit, when the mean free path is long, the radiation is absorbed throughout acting to heat the clump. This heating explodes the gas clump. Careful selection of parameters, such as foam density or source temperature, allow the experimental platform to access different hydrodynamic regimes. The stellar radiation source is mimicked by a laser irradiated thin gold foil. This will provide a source of thermal x-rays (around 100 eV). The gas clump is mimicked by a low-density foam around 0.12 g/cc. Simulations were done using radiation hydrodynamics codes to tune the experimental parameters. The experiment will be carried out at the Omega laser facility on OMEGA 60. Funding acknowledgements: This work is funded by the U.S. DOE, through the NNSA-DS and SC-OFES Joint Program in HEDPLP, Grant No. DE-NA0001840, and the NLUF Program, Grant No. DE-NA0000850, and through LLE, University of Rochester by the NNSA/OICF under Agreement No. DE-FC52-08NA28302.

Experiment to measure oxygen opacity at high density and temperature

NASA Astrophysics Data System (ADS)

Keiter, Paul; Mussack, Katie; Orban, Chris; Colgan, James; Ducret, Jean-Eric; Fontes, Christopher J.; Guzik, Joyce Ann; Heeter, Robert F.; Kilcrease, Dave; Le Pennec, Maelle; Mancini, Roberto; Perry, Ted; Turck-Chièze, Sylvaine; Trantham, Matt

2017-06-01

In recent years, there has been a debate over the abundances of heavy elements (Z >2) in the solar interior. Recent solar atmosphere models [Asplund 2009] find a significantly lower abundance for C, N, and O compared to models used roughly a decade ago. This discrepancy has led to an investigation of opacities through laboratory experiments and improved opacity models for many of the larger contributors to the sun’s opacity, including iron and oxygen. Recent opacity measurements of iron disagree with opacity model predictions [Bailey et al, 2015]. Although these results are still controversial, repeated scrutiny of the experiment and data has not produced a conclusive reason for the discrepancy. New models have been implemented in the ATOMIC opacity code for C, O and Fe to address the solar abundance issue [Colgan, 2013]. Armstrong et al [2014] have also implemented changes in the ATOMIC code for low-Z elements. However, no data currently exists to test the low-Z material models in the regime relevant to the solar convection zone. We present an experimental design using the opacity platform developed at the National Ignition Facility to study the oxygen opacity at densities and temperatures near the solar convection zone conditions.This work is funded by the U.S. DOE, through the NNSA-DS and SC-OFES Joint Program in HEDPLP, grant No. DE-NA0001840, and the NLUF Program, grant No. DE-NA0000850, and through LLE, University of Rochester by the NNSA/OICF under Agreement No. DE-FC52-08NA28302.

Measurements of Laser Generated X-ray Spectra from Irradiated Gold Foils

NASA Astrophysics Data System (ADS)

Davis, Joshua; Keiter, Paul; Drake, Paul; Klein, Sallee

2015-11-01

Soft x-ray sources may provide a means of driving photoionization fronts in materials with a Z >2. To generate these soft x-rays at a traditional UV laser facility, a gold converter foil can be implemented that absorbs the UV photons and heats up to act as a quasi-continuum blackbody emitter with a characteristic temperature of ~ 100eV. However, it takes time for the heating wave to propagate through the foil, with thicker foils having a longer delay before measureable emission is produced. Prior work has studied the emission characteristics of foil x-ray sources but was limited to laser pulses of 1ns or less. Our interest is in long duration sources (>1ns) which requires the use of thicker Au foils. To better understand how the increased foil thickness affects emission we have performed experiments at the Omega-60 laser facility studying the x-ray intensity and total emission time of 0.5, 1.0, and 2.0 μm thick gold foils driven by a 2kJ, 6ns laser pulse. This presentation will discuss the results of these experiments and will include a discussion of how these results compare with theoretical predictions. This work is funded by the U.S. DOE, through the NNSA-DS and SC-OFES Joint Program in HEDPLP, grant No. DE-NA0001840, and the NLUF Program, grant No. DE-NA0000850, and through LLE, Univ of Rochester by the NNSA/OICF under Agreement No. DE-FC52-08NA28302.

NA-42 TI Shared Software Component Library FY2011 Final Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Knudson, Christa K.; Rutz, Frederick C.; Dorow, Kevin E.

The NA-42 TI program initiated an effort in FY2010 to standardize its software development efforts with the long term goal of migrating toward a software management approach that will allow for the sharing and reuse of code developed within the TI program, improve integration, ensure a level of software documentation, and reduce development costs. The Pacific Northwest National Laboratory (PNNL) has been tasked with two activities that support this mission. PNNL has been tasked with the identification, selection, and implementation of a Shared Software Component Library. The intent of the library is to provide a common repository that is accessiblemore » by all authorized NA-42 software development teams. The repository facilitates software reuse through a searchable and easy to use web based interface. As software is submitted to the repository, the component registration process captures meta-data and provides version control for compiled libraries, documentation, and source code. This meta-data is then available for retrieval and review as part of library search results. In FY2010, PNNL and staff from the Remote Sensing Laboratory (RSL) teamed up to develop a software application with the goal of replacing the aging Aerial Measuring System (AMS). The application under development includes an Advanced Visualization and Integration of Data (AVID) framework and associated AMS modules. Throughout development, PNNL and RSL have utilized a common AMS code repository for collaborative code development. The AMS repository is hosted by PNNL, is restricted to the project development team, is accessed via two different geographic locations and continues to be used. The knowledge gained from the collaboration and hosting of this repository in conjunction with PNNL software development and systems engineering capabilities were used in the selection of a package to be used in the implementation of the software component library on behalf of NA-42 TI. The second task managed by PNNL is the development and continued maintenance of the NA-42 TI Software Development Questionnaire. This questionnaire is intended to help software development teams working under NA-42 TI in documenting their development activities. When sufficiently completed, the questionnaire illustrates that the software development activities recorded incorporate significant aspects of the software engineering lifecycle. The questionnaire template is updated as comments are received from NA-42 and/or its development teams and revised versions distributed to those using the questionnaire. PNNL also maintains a list of questionnaire recipients. The blank questionnaire template, the AVID and AMS software being developed, and the completed AVID AMS specific questionnaire are being used as the initial content to be established in the TI Component Library. This report summarizes the approach taken to identify requirements, search for and evaluate technologies, and the approach taken for installation of the software needed to host the component library. Additionally, it defines the process by which users request access for the contribution and retrieval of library content.« less

The Offline Software Framework of the NA61/SHINE Experiment

NASA Astrophysics Data System (ADS)

Sipos, Roland; Laszlo, Andras; Marcinek, Antoni; Paul, Tom; Szuba, Marek; Unger, Michael; Veberic, Darko; Wyszynski, Oskar

2012-12-01

NA61/SHINE (SHINE = SPS Heavy Ion and Neutrino Experiment) is an experiment at the CERN SPS using the upgraded NA49 hadron spectrometer. Among its physics goals are precise hadron production measurements for improving calculations of the neutrino beam flux in the T2K neutrino oscillation experiment as well as for more reliable simulations of cosmic-ray air showers. Moreover, p+p, p+Pb and nucleus+nucleus collisions will be studied extensively to allow for a study of properties of the onset of deconfinement and search for the critical point of strongly interacting matter. Currently NA61/SHINE uses the old NA49 software framework for reconstruction, simulation and data analysis. The core of this legacy framework was developed in the early 1990s. It is written in different programming and scripting languages (C, pgi-Fortran, shell) and provides several concurrent data formats for the event data model, which includes also obsolete parts. In this contribution we will introduce the new software framework, called Shine, that is written in C++ and designed to comprise three principal parts: a collection of processing modules which can be assembled and sequenced by the user via XML files, an event data model which contains all simulation and reconstruction information based on STL and ROOT streaming, and a detector description which provides data on the configuration and state of the experiment. To assure a quick migration to the Shine framework, wrappers were introduced that allow to run legacy code parts as modules in the new framework and we will present first results on the cross validation of the two frameworks.

Predictors of Survival among Adult Ethiopian Patients in the National ART Program at Seven University Teaching Hospitals: A Prospective Cohort Study.

PubMed

Fekade, Daniel; Weldegebreal, Teklu; Teklu, Alula M; Damen, Melake; Abdella, Saro; Baraki, Nega; Belayhun, Bekele; Berhan, Eyoel; Kebede, Amha; Assefa, Yibeltal

2017-02-01

In Ethiopia, the publicly funded antiretroviral treatment (ART) program was started in 2005. Two hundred seventy-five thousand patients were enrolled in the national ART program by 2012. However, there is limited data on mortality and predictors of death among adult patients in the ART program. The study aimed to estimate mortality and risk factors for death among adult, ART-naïve patients, started in the national ART program from January 2009 to July 2013. Multi-site, prospective, observational cohort study of adult, age > 18 years, ART-naïve patients, started in the national ART program at seven university-affiliated hospitals from January 2009 - July 2013. Kaplan-Meier and Cox regression analyses were used to estimate survival and determine risk factors for death. A total of 976 patients, 594 females (60.9 %), were enrolled into the study. Median age of the cohort was 33years. The median CD4 count at start of ART was 144 cells/µl (interquartile range (IQR) 78-205), and 34.2% (330/965) had CD4 < 100. Sixty-three percent (536/851) had viral load greater than 5 log copies/ml (IQR 4.7-5.7) at base line. One hundred and one deaths were recorded during follow-up period, all-cause mortality rate 10.3%; 5.4 deaths/100 person years of observation, 95% confidence interval 4.4-6.5. Seventy percent of the deaths occurred within six months of starting ART. Cox regression analyses showed that the following measures independently predicted mortality: age >51 years, (Adjusted Hazard Ratio (AHR) 4.01, P=0.003), WHO stages III&IV, (AHR 1.76, p = 0.025), CD4 count, <100, (AHR 2.36, p =0.006), and viral load >5 log copies /ml (CHR 1.71, p = 0.037). There is high early on- ART mortality in patients presenting with advanced immunodeficiency. Detecting cases and initiating ART before onset of advanced immunodeficiency might improve survival.

Understanding charge transfer of Li+ and Na+ ions scattered from metal surfaces with high work function

NASA Astrophysics Data System (ADS)

Chen, Lin; Wu, Wen-Bin; Liu, Pin-Yang; Xiao, Yun-Qing; Li, Guo-Peng; Liu, Yi-Ran; Jiang, Hao-Yu; Guo, Yan-Ling; Chen, Xi-Meng

2016-08-01

For Li+ and Na+ ions scattered from high work function metal surfaces, efficient neutralization is observed, and it cannot be explained by the conventional free electron model. In order to explain these experimental data, we investigate the velocity-dependent neutral fraction with the modified Brako-Newns (BN) model. The calculated results are in agreement with the experimental data. We find that the parallel velocity effect plays an important role in neutralizing the Li+ and Na+ ions for large angle scattering. The nonmonotonic velocity behavior of neutral fraction is strongly related to the distance-dependent coupling strength between the atomic level and metal states. Project supported by the National Natural Science Foundation of China (Grant Nos. 11405078 and 11474140), the Fundamental Research Funds for the Central Universities, China (Grant Nos. lzujbky-2014-169 and lzujbky-2015-244), the Project sponsored by the Scientific Research Foundation for the Returned Overseas Chinese Scholars, the State Education Ministry, and the National Students’ Innovation and Entrepreneurship Training Program (Grant Nos. 201410730069 and 201510730078).

Analysis of Precursor Properties of mixed Al/Alumel Cylindrical Wire Arrays*

NASA Astrophysics Data System (ADS)

Stafford, A.; Safronova, A. S.; Kantsyrev, V. L.; Esaulov, A. A.; Weller, M. E.; Shrestha, I.; Osborne, G. C.; Shlyaptseva, V. V.; Keim, S. F.; Coverdale, C. A.; Chuvatin, A. S.

2012-10-01

Previous studies of mid-Z (Cu and Ni) cylindrical wire arrays (CWAs) on Zebra have found precursors with high electron temperatures of >300 eV. However, past experiments with Al CWAs did not find the same high temperature precursors. New precursor experiments using mixed Al/Alumel (Ni 95%, Si 2%, and Al 2%) cylindrical wire arrays have been performed to understand how the properties of L-shell Ni precursor will change and whether Al precursor will be observed. Time gated spectra and pinholes are used to determine precursor plasma conditions for comparison with previous Alumel precursor experiments. A full diagnostic set which included more than ten different beam-lines was implemented. Future work in this direction is discussed. [4pt] *This work was supported by NNSA under DOE Cooperative Agreements DE-FC52-06NA27588, and in part by DE-FC52-06NA27586, and DE-FC52-06NA27616. Sandia is a multi-program laboratory operated by Sandia Corporation, a Lockheed Martin Company, for the United States Department of Energy under Contract DE-AC04-94AL85000.

Effective atomic numbers and electron densities of bioactive glasses for photon interaction

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shantappa, Anil, E-mail: anilmalipatil@yahoo.co.in; Hanagodimath, S. M., E-mail: smhmath@rediffmail.com

2015-08-28

This work was carried out to study the nature of mass attenuation coefficient of bioactive glasses for gamma rays. Bioactive glasses are a group of synthetic silica-based bioactive materials with unique bone bonding properties. In the present study, we have calculated the effective atomic number, electron density for photon interaction of some selected bioactive glasses viz., SiO{sub 2}-Na{sub 2}O, SiO{sub 2}-Na{sub 2}O-CaO and SiO{sub 2}-Na{sub 2}O-P{sub 2}O{sub 5} in the energy range 1 keV to 100 MeV. We have also computed the single valued effective atomic number by using XMuDat program. It is observed that variation in effective atomic number (Z{submore » PI,} {sub eff}) depends also upon the weight fractions of selected bioactive glasses and range of atomic numbers of the elements. The results shown here on effective atomic number, electron density will be more useful in the medical dosimetry for the calculation of absorbed dose and dose rate.« less

Long-term in vivo carcinogenicity tests of potassium bromate, sodium hypochlorite, and sodium chlorite conducted in Japan.

PubMed Central

Kurokawa, Y; Takayama, S; Konishi, Y; Hiasa, Y; Asahina, S; Takahashi, M; Maekawa, A; Hayashi, Y

1986-01-01

Long-term in vivo carcinogenicity tests of potassium bromate (KBrO3), sodium hypochlorite (NaClO), and sodium chlorite (NaClO2) have been conducted in Japan from 1977 to 1985. In these investigations, groups of approximately 50 male and 50 female F344 rats or B6C3F1 mice were given solutions of the compounds as their drinking water ad libitum at two dose levels determined on the basis of preliminary 13-week tests. Control animals were given distilled water. The carcinogenic potential of KBrO3 was tested by administering doses of 500 or 250 ppm to rats for 110 weeks. Significantly elevated incidences of renal cell tumors in males and females and mesotheliomas of the peritoneum in males as compared to controls were observed. When female mice were given KBrO3 at doses of 1000 or 500 ppm for 78 weeks, no significant differences in tumor incidences between experimental and control groups were apparent. NaClO was administered to male and female rats, respectively, at doses of 1000 or 500 ppm and 2000 or 1000 ppm for 104 weeks. In mice, NaClO was given at doses of 1000 or 500 ppm to either sex for 103 weeks. The incidences of tumors in NaClO-treated and control animals of both sexes were not significantly different in both rat and mouse studies. NaClO2 was given to rats of both sexes at a dose of 600 or 300 ppm for 85 weeks. No statistically significant differences were observed in the incidences of tumor formation between NaClO2-treated and control groups of both sexes. NaClO2 was administered to mice at a concentration of 500 or 250 ppm for 85 weeks. In males, the combined incidences of hyperplastic nodules and hepatocellular carcinomas of the liver in a low-dose group, and adenomas and adenocarcinomas of the lung in a high-dose group, were marginally increased compared to controls (p less than 0.05). However, these incidences in treated males were within the range of values of historical control data in our program. We concluded that KBrO3 was carcinogenic in rats of both sexes. NaClO was not carcinogenic in either rats and or mice under the conditions of the present studies. Although NaClO2 was shown to be noncarcinogenic in rats, the results for mice were evaluated as inconclusive. Also the results of two-stage mouse skin carcinogenesis using KBrO3, NaClO, and NaClO2 are presented. The necessity for further testing of oxidant chemicals to determine potential carcinogenic and/or promoting effects is suggested in view of the recently proposed role of active oxygen species in carcinogenesis. Images FIGURE 3. FIGURE 4. PMID:3816726

Constraining National Health Care Expenditures. Achieving Quality Care at an Affordable Cost.

DTIC Science & Technology

1985-09-30

Medicaid (federal/state) 10.8 Other state/local government programs 5.1 Other federal programs 5.4 Philanthropy and industrial in-plant 1.2 .- Source: U.S...expenditures. Projections of future outlays and income for the Medicare Trust Fund indicate serious financing problems by the . mid to late 1990’s. The...7.1 0 France 6.4 7.9 23 West Germany 6.4 9.2 44 Italy 6 .1a 6.4 5 Netherlands 6.3 8.2 30 Sweden 7.4 9.8 32 Switzerland n/a 6.9 United Kingdom 4.3 5.2

Experimental and theoretical deposition rates from salt-seeded combustion gases of a Mach 0.3 burner rig

NASA Technical Reports Server (NTRS)

Santoro, G. J.; Kohl, F. J.; Stearns, C. A.; Gokoglu, S. A.; Rosner, D. E.

1984-01-01

Deposition rates on platinum-rhodium cylindrical collectors rotating in the cross streams of the combustion gases of a salt-seeded Mach 0.3 burner rig were determined. The collectors were internally air cooled so that their surface temperatures could be widely varied while they were exposed to constant combustion gas temperatures. The deposition rates were compared with those predicted by the chemically frozen boundary layer (CFBL) computer program, which is based on multicomponent vapor transport through the boundary layer. Excellent agreement was obtained between theory and experiment for the NaCl-seeded case, but the agreement lessened as the seed was changed to synthetic sea salt, NaNO3, and K2SO4, respectively, and was particularly poor in the case of Na2SO4. However, when inertial impaction was assumed to be the deposition mechanism for the Na2SO4 case, the predicted rates agreed well with the experimental rates. The former were calculated from a mean particle diameter that was derived from the measured intial droplet size distribution of the solution spray. Critical experiments showed that liquid phase deposits were blown off the smooth surface of the platinum-rhodium collectors by the aerodynamic shear forces of the high-velocity combustion gases but that rough or porous surfaces retained their liquid deposits.

Molecular basis of sodium butyrate-dependent proapoptotic activity in cancer cells.

PubMed

Pajak, B; Orzechowski, A; Gajkowska, B

2007-01-01

This review outlines the molecular events that accompany the antitumor action of sodium butyrate (NaBt). Butyrate, a low-molecular weight four-carbon chain volatile fatty acid (VFA) has been previously shown to withdraw cells from cell cycle or to promote cell differentiation, and finally to induce programmed cell death. Recent advances in molecular biology indicate, that this product of large bowel microbial fermentation of dietary fiber, might evoke the above-mentioned effects by indirect action on genes. NaBt was shown to inhibit histone deacetylase activity, allowing DNA binding of several transcription factors. Higher genomic activity leads to the higher expression of proapoptotic genes, higher level of their protein products and elevated sensitivity to death ligand-induced apoptosis. Cancer cells might be arrested in G1 phase of cell cycle in a p21-dependent manner. Proapoptotic activity of NaBt includes higher expression of membrane death receptors (DR4/5), higher level and activation of Smad3 protein in TGF-beta-dependent apoptotic pathway, lower level of antiapoptotic proteins (cFLIP, XIAP) and activation ofproapoptotic tBid protein. Thus, both intrinsic and extrinsic apoptotic pathways are stimulated to ampify the apoptotic signals. These effects are specific for tumor but not for regular cells. Unique properties of NaBt make this agent a promising metabolic inhibitor to retard tumorigenesis to suppress tumor growth.

Basic research and data analysis for the National Geodetic Satellite Program

NASA Technical Reports Server (NTRS)

1972-01-01

Investigations of triangulation nets and scaling are reported. Adjustment of the BC-4 worldwide geometric satellite triangulation net is described, along with procedures for correcting type II data and the contents of magnetic tapes containing data from the Pageos network. Computational steps for the further reduction of partially reduced satellite image plate coordinates are outlined. The problem of improving existing triangulation systems by means of satellite super-control points was studied. The SAO-69 geometric solution was scaled with C-band radar data, resulting in SAO and C-band adjustment compatible with one another in the Western Hemisphere. The North America solution NA-6, obtained from GEOS 1 data, was readjusted with new heights as constraints on all 30 optical stations and is referred to as the NA-8 solution.

The Workshop on Principles and Practice of Constraint Programming (2nd) Held in Orcas Island, Washington on 2-4 May 1994

DTIC Science & Technology

1994-05-04

gen- word pussies . In Proceedings of the Eighth Na- erate fewer than c clauses so the boundary of the grid tional Conference on Artificial Intelligence...checking. (2) (FC - NI), forward-checking search branches are bundled and visited once. with the advantage of neighborhood inter- If a dead -end occurs

Epiphytic Macrolichen Community Composition Database—epiphytic lichen synusiae in forested areas of the US

Treesearch

Sarah. Jovan

2012-01-01

The Forest Inventory and Analysis (FIA) Program's Lichen Communities Indicator is used for tracking epiphytic macrolichen diversity and is applied for monitoring air quality and climate change effects on forest health in the United States. Started in 1994, the Epiphytic Macrolichen Community Composition Database (GIVD ID NA-US-012) now has over 8,000 surveys of...

Learning To Lead: A Maine Staff Development Program Empowers Teachers to Become Leaders

ERIC Educational Resources Information Center

Ray, Doris; Pike, Ann

2004-01-01

On the surface, learning and leading may appear to be opposites. Learners are commonly thought to be na?ve and innocent. Leaders are expected to possess special skills and knowledge. However, these apparent opposites may be like two sides of the same coin, a dynamic combination that generates powerful results. A Maine nonprofit has created a…

NoSQL Data Store Technologies

DTIC Science & Technology

2014-09-01

NoSQL Data Store Technologies John Klein, Software Engineering Institute Patrick Donohoe, Software Engineering Institute Neil Ernst...REPORT TYPE N/A 3. DATES COVERED 4. TITLE AND SUBTITLE NoSQL Data Store Technologies 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT...distribute data 4. Data Replication – determines how a NoSQL database facilitates reliable, high performance data replication to build

Alka-Seltzer Fizzing--Determination of Percent by Mass of NaHCO3 in Alka-Seltzer Tablets: An Undergraduate General Chemistry Experiment.

ERIC Educational Resources Information Center

Chen, Yueh-Huey; Yaung, Jing-Fun

2002-01-01

Presents a general chemistry stoichiometry experiment using materials involved in everyday life. From this activity, students learn that a chemical reaction occurs when an Alka-Seltzer tablet is dropped into water. Students also practice plotting experimental data through the use of a graphing program. Interpretation of the graph helps them…

Inadequate Controls Over the DoD Service-Disabled Veteran-Owned Small Business Set-Aside Program Allow Ineligible Contractors to Receive Contracts

DTIC Science & Technology

2012-02-29

status, which we identified from the red flags generated during our review. Table 2. Awards to Contractors That Potentially Misstated Their SDVOSB...verification of the SDVOSB stutus is not required by the FAR. NA VAIR Response: C:oncur. While the contracti ng officer complied with aJI applicable

The Effectiveness of an Early-Grade Literacy Intervention on the Cognitive Achievement of Brazilian Students

ERIC Educational Resources Information Center

Costa, Leandro Oliveira; Carnoy, Martin

2015-01-01

Beginning in 2007, the Literacy Program at the Right Age (Pacto pela Alfabetização na Idade Certa [PAIC]) in Brazil's Ceará state required municipal schools to implement a tiered, whole-school early-grade literacy intervention. This intervention was complemented by other policies to help municipalities improve student achievement. The present…

Cargo Movement Operations System (CMOS). Software User’s Manual

DTIC Science & Technology

1990-06-27

RATIONALE: N/A CMOS PMO ACCEPTS COMMENT: YES [ ] NO [ ] ERCI ACCEPTS COMMENT: YES [ ] NO [ ] COMMENT DISPOSITION: ACCEPT [ ] REJECT [ ] COMMENT STATUS...NO [ ] ERCI ACCEPTS COMMENT: YES [ ] NO [ ] COMMENT DISPOSITION: COMMENT STATUS: OPEN [ ] CLOSED [ 3 ORIGINATOR CONTROL NUMBER: SUM-0003 PROGRAM...3.1.11. RATIONALE: Clarity. CMOS PMO ACCEPTS COMMENT: YES [ ] NO [ ] ERCI ACCEPTS COMMENT: YES [ ] NO [ ] COMMENT DISPOSITION: COMMENT STATUS: OPEN

Cargo Movement Operations System (CMOS). Software Design Document

DTIC Science & Technology

1990-04-29

order. RATIONALE: N/A CMOS PMO ACCEPTS COMMENT: YES [ ] NO [ ] ERCI ACCEPTS COMMENT: YES [ ] NO [ ] COMMENT DISPOSITION: ACCEPT [ ] REJECT [ ] COMMENT...inadvertently omitted from the table. CMOS PMO ACCEPTS COMMENT: YES [ ] NO [ ] ERCI ACCEPTS COMMENT: YES [ ] NO [ ] COMMENT DISPOSITION: COMMENT STATUS: OPEN...YES [ ] NO [ ] COMMENT DISPOSITION: COMMENT STATUS: OPEN [ ] CLOSED [ ] ORIGINATOR CONTROL NUMBER: SDDI-0005 PROGRAM OFFICE CONTROL NUMBER: DATA ITEM

Joint Services Electronics Program.

DTIC Science & Technology

1985-12-31

year a comprehensive experimental study of the collision- enhanced Hanle-type resonances in Na vapor with various buffer gases has been completed...demonstrated theoretically that the collision-enhanced Hanle resonances are equivalent to the phenomenon of collision-induced transverse optical pumping. The...for the sensitivity of the mean sojourn times. We also developed a set of new equations based on perturbation analysis which calculates theoretically

Application of long-term cultured interferon-gamma enzyme-linked immunospot assay for assessing effector and memory T cell responses in cattle

USDA-ARS?s Scientific Manuscript database

Effector and memory T cells are generated through developmental programing of naïve cells following antigen recognition. If the infection is controlled, up to 95% of the T cells generated during the expansion phase are eliminated (i.e., contraction phase) and memory T cells remain, sometimes for a l...

Building the Business Case

DTIC Science & Technology

2001-05-15

Building the Business Case Dr Robin Miller Centre for Defence Analysis Report Documentation Page Report Date 15052001 Report Type N/A Dates Covered...from... to) - Title and Subtitle Building the Business Case Contract Number Grant Number Program Element Number Author(s) Miller, Robin...Trade-offs between men/materiel/process can be made coherent – auditable links to operational risk can be maintained Business Case Challenge for SBA

The good pharmacy practice on Einstein Program at Paraisópolis Community.

PubMed

Oliveira, Lara Tânia de Assumpção Domingues Gonçalves de; Silva, Camila Pontes da; Guedes, Maria das Vitorias; Sousa, Ana Célia de Oliveira; Sarno, Flávio

2016-01-01

To describe indicators and processes developed and implemented for pharmaceutical assistance at the Einstein Program at Paraisópolis Community pharmacy. This was a descriptive study of retrospective data from January 2012 to December 2015. Data were obtained from spreadsheets developed for monitoring the productivity and care quality provided at the pharmacy. The evaluated variables were pharmaceutical assistance to prescription, pharmaceutical intervention, orientation (standard and pharmaceutical) and pharmaceutical orientation rate. The pharmacy assisted, on average, 2,308 prescriptions monthly, dispensing 4,871 items, including medications, materials and food supplements. Since March 2015, virtually, the pharmacist analyzed all prescriptions, prior to dispensing. In the analyzed period, there was an increase in monthly pharmaceutical interventions from 7 to 32 on average, and, although there was a decrease in the number of standard orientation, the pharmaceutical orientation had an increase, causing a rise of pharmaceutical orientation rate from 4 to 11%. The processes developed and implemented at the program pharmacy sought to follow the good pharmacy practice, and help patients to make the best use of their medications. Descrever os indicadores e os processos desenvolvidos e implantados para assistência farmacêutica na farmácia do Programa Einstein na Comunidade de Paraisópolis. Tratase de um estudo descritivo de dados retrospectivos de janeiro de 2012 a dezembro de 2015. Os dados foram obtidos de planilhas desenvolvidas para acompanhamento da produtividade e da qualidade de assistência prestada na farmácia. As variáveis avaliadas foram: atenção farmacêutica à prescrição, intervenção farmacêutica, orientação (padrão e farmacêutica) e taxa de orientação farmacêutica. A farmácia atendeu, em média, 2.308 prescrições ao mês, dispensando 4.871 itens, incluindo medicamentos, materiais e suplementos alimentares. Desde março de 2015, praticamente todas as prescrições foram analisadas pelo farmacêutico antes da dispensação. Houve incremento nas intervenções farmacêuticas mensais, de 7 para 32 em média e, apesar de ter havido diminuição no número de orientações padrão, a orientação farmacêutica aumentou, fazendo com que a taxa de orientação subisse de 4 para 11%. Os indicadores e os processos desenvolvidos e implantados na farmácia do programa procuraram seguir as boas práticas de farmácia e ajudar os pacientes a fazerem melhor uso de seus medicamentos.

Improved charge breeding efficiency of light ions with an electron cyclotron resonance ion source

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vondrasek, R.; Kutsaev, Sergey; Delahaye, P.

2012-11-15

The Californium Rare Isotope Breeder Upgrade is a new radioactive beam facility for the Argonne Tandem Linac Accelerator System (ATLAS). The facility utilizes a {sup 252}Cf fission source coupled with an electron cyclotron resonance ion source to provide radioactive beam species for the ATLAS experimental program. The californium fission fragment distribution provides nuclei in the mid-mass range which are difficult to extract from production targets using the isotope separation on line technique and are not well populated by low-energy fission of uranium. To date the charge breeding program has focused on optimizing these mid-mass beams, achieving high charge breeding efficienciesmore » of both gaseous and solid species including 14.7% for the radioactive species {sup 143}Ba{sup 27+}. In an effort to better understand the charge breeding mechanism, we have recently focused on the low-mass species sodium and potassium which up to present have been difficult to charge breed efficiently. Unprecedented charge breeding efficiencies of 10.1% for {sup 23}Na{sup 7+} and 17.9% for {sup 39}K{sup 10+} were obtained injecting stable Na{sup +} and K{sup +} beams from a surface ionization source.« less

Improved charge breeding efficiency of light ions with an electron cyclotron resonance ion source

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vondrasek, R.; Delahaye, P.; Kutsaev, Sergey

2012-11-01

The Californium Rare Isotope Breeder Upgrade is a new radioactive beam facility for the Argonne Tandem Linac Accelerator System (ATLAS). The facility utilizes a 252Cf fission source coupled with an electron cyclotron resonance ion source to provide radioactive beam species for the ATLAS experimental program. The californium fission fragment distribution provides nuclei in the mid-mass range which are difficult to extract from production targets using the isotope separation on line technique and are not well populated by low-energy fission of uranium. To date the charge breeding program has focused on optimizing these mid-mass beams, achieving high charge breeding efficiencies ofmore » both gaseous and solid species including 14.7% for the radioactive species 143Ba27+. In an effort to better understand the charge breeding mechanism, we have recently focused on the low-mass species sodium and potassium which up to present have been difficult to charge breed efficiently. Unprecedented charge breeding efficiencies of 10.1% for 23Na7+ and 17.9% for 39K10+ were obtained injecting stable Na+ and K+ beams from a surface ionization source.« less

A New Way to Generate Collimated Plasma Jets?

NASA Astrophysics Data System (ADS)

Young, Rachel; Kuranz, C. C.; Sweeney, R. M.; Drake, R. P.

2012-05-01

We may have a new way to generate collimated, high-Mach-number plasma jets for laboratory astrophysics experiments. Analytic calculations show that irradiating the rear side of a cone-shaped foil can produce a collimated plasma jet with a Mach number of more than 2. Preliminary numeric simulations confirm this. We intend to test this method with a day of experiments at OMEGA (Laboratory for Laser Energetics, Rochester, New York) in April 2012; results may be available in time for this meeting. If successful, this will be the first step in an experimental campaign to investigate the affects of magnetic fields on mixing plasma jets. We hope to create a swirling disk of magnetized plasma_and possibly witness the turbulent dynamo_by firing roughly half a dozen such jets towards each other. However, for such an experiment to succeed, the disk must rotate more quickly than it expands, requiring the contributing jets to have M > 2. This work is funded by the NNSA-DS and SC-OFES Joint Program in High-Energy-Density Laboratory Plasmas, grant number DE-FG52-09NA29548, and by the National Laser User Facility Program, grant number DE-NA0000850.

Proportional-Integral-Derivative (PID) Temperature Control and Data Acquisition System for Faraday Filter based Sodium Spectrometer

NASA Astrophysics Data System (ADS)

Semerjyan, Vardan; Yuan, Tao

2011-04-01

Sodium (Na) Faraday filters based spectrometer is a relatively new instrument to study sodium nightglow as well as sodium and oxygen chemistry in the mesopause region. Successful spectrometer measurement demands highly accurate control of filter temperature. The ideal, long-term operation site for the Na spectrometer is an isolated location with minimum nocturnal sky background. Thus, the remote control of the filter temperature is a requirement for such operation, whereas current temperature controllers can only be operated manually. The proposed approach is aimed to not only enhance the temperature control, but also achieve spectrometer's remote and autonomous operation. In the meantime, the redesign should relief the burden of the cost for multi temperature controllers. The program will give to the operator flexibility in setting the operation temperatures of the Faraday filters, monitoring the temperature variations, and logging the data during the operation. Research will make diligent efforts to attach preliminary data analysis subroutine to the main control program. The real-time observation results will be posted online after the observation is completed. This approach also can be a good substitute for the temperature control system currently used to run the Lidar system at Utah State University (USU).

EGRET High Energy Capability and Multiwavelength Flare Studies and Solar Flare Proton Spectra

NASA Technical Reports Server (NTRS)

Chupp, Edward L.

1997-01-01

UNH was assigned the responsibility to use their accelerator neutron measurements to verify the TASC response function and to modify the TASC fitting program to include a high energy neutron contribution. Direct accelerator-based measurements by UNH of the energy-dependent efficiencies for detecting neutrons with energies from 36 to 720 MeV in NaI were compared with Monte Carlo TASC calculations. The calculated TASC efficiencies are somewhat lower (by about 20%) than the accelerator results in the energy range 70-300 MeV. The measured energy-loss spectrum for 207 MeV neutron interactions in NaI were compared with the Monte Carlo response for 200 MeV neutrons in the TASC indicating good agreement. Based on this agreement, the simulation was considered to be sufficiently accurate to generate a neutron response library to be used by UNH in modifying the TASC fitting program to include a neutron component in the flare spectrum modeling. TASC energy-loss data on the 1991 June 11 flare was transferred to UNH. Also included appendix: Gamma-rays and neutrons as a probe of flare proton spectra: the solar flare of 11 June 1991.

Genotypic variation in response to salinity in a new sexual germplasm of Cenchrus ciliaris L.

PubMed

Quiroga, Mariana; Tommasino, Exequiel; Griffa, Sabrina; Ribotta, Andrea; Colomba, Eliana López; Carloni, Edgardo; Grunberg, Karina

2016-05-01

As part of a breeding program for new salt-tolerant sexual genotypes of Cenchrus ciliaris L., here we evaluated the salt-stress response of two new sexual hybrids, obtained by controlled crosses, at seedling and germination stages. A seedling hydroponic experiment with 300 mM NaCl was performed and physiological variables and growth components were evaluated. While salt-treated sexual material did not show a decrease in productivity with respect to control plants, a differential response in some physiological characteristics was observed. Sexual hybrid 1-9-1 did not suffer oxidative damage and its proline content did not differ from that of control treatment. By contrast, sexual hybrid 1-7-11 suffered oxidative damage and accumulated proline, maintaining its growth under saline stress. At the germination stage, sexual hybrid 1-9-1 presented the highest Germination Rate Index at the maximum NaCl concentration assayed, suggesting an ecological advantage in this genotype. These new sexual resources are promising maternal parental with differential response to salt and could be incorporated in a breeding program of C. ciliaris in the search of new genotypes tolerant to salinity. Copyright © 2016 Elsevier Masson SAS. All rights reserved.

Kelvin-Helmholtz evolution in subsonic cold streams feeding galaxies

NASA Astrophysics Data System (ADS)

Angulo, Adrianna; Coffing, S.; Kuranz, C.; Drake, R. P.; Klein, S.; Trantham, M.; Malamud, G.

2017-10-01

The most prolific star formers in cosmological history lie in a regime where dense filament structures carried substantial mass into the galaxy to sustain star formation without producing a shock. However, hydrodynamic instabilities present on the filament surface limit the ability of such structures to deliver dense matter deeply enough to sustain star formation. Simulations lack the finite resolution necessary to allow fair treatment of the instabilities present at the stream boundary. Using the Omega EP laser, we simulate this mode of galaxy formation with a cold, dense, filament structure within a hotter, subsonic flow and observe the interface evolution. Machined surface perturbations stimulate the development of the Kelvin-Helmholtz (KH) instability due to the resultant shear between the two media. A spherical crystal imaging system produces high-resolution radiographs of the KH structures along the filament surface. The results from the first experiments of this kind, using a rod with single-mode, long-wavelength modulations, will be discussed. This work is funded by the U.S. Department of Energy, through the NNSA-DS and SC-OFES Joint Program in High-Energy-Density Laboratory Plasmas, Grant Number DE-NA0002956, and the National Laser User Facility Program, Grant Number DE-NA0002719, and through.

Impact of a Telehealth Program With Voice Recognition Technology in Patients With Chronic Heart Failure: Feasibility Study.

PubMed

Lee, Heesun; Park, Jun-Bean; Choi, Sae Won; Yoon, Yeonyee E; Park, Hyo Eun; Lee, Sang Eun; Lee, Seung-Pyo; Kim, Hyung-Kwan; Cho, Hyun-Jai; Choi, Su-Yeon; Lee, Hae-Young; Choi, Jonghyuk; Lee, Young-Joon; Kim, Yong-Jin; Cho, Goo-Yeong; Choi, Jinwook; Sohn, Dae-Won

2017-10-02

Despite the advances in the diagnosis and treatment of heart failure (HF), the current hospital-oriented framework for HF management does not appear to be sufficient to maintain the stability of HF patients in the long term. The importance of self-care management is increasingly being emphasized as a promising long-term treatment strategy for patients with chronic HF. The objective of this study was to evaluate whether a new information communication technology (ICT)-based telehealth program with voice recognition technology could improve clinical or laboratory outcomes in HF patients. In this prospective single-arm pilot study, we recruited 31 consecutive patients with chronic HF who were referred to our institute. An ICT-based telehealth program with voice recognition technology was developed and used by patients with HF for 12 weeks. Patients were educated on the use of this program via mobile phone, landline, or the Internet for the purpose of improving communication and data collection. Using these systems, we collected comprehensive data elements related to the risk of HF self-care management such as weight, diet, exercise, medication adherence, overall symptom change, and home blood pressure. The study endpoints were the changes observed in urine sodium concentration (uNa), Minnesota Living with Heart Failure (MLHFQ) scores, 6-min walk test, and N-terminal prohormone of brain natriuretic peptide (NT-proBNP) as surrogate markers for appropriate HF management. Among the 31 enrolled patients, 27 (87%) patients completed the study, and 10 (10/27, 37%) showed good adherence to ICT-based telehealth program with voice recognition technology, which was defined as the use of the program for 100 times or more during the study period. Nearly three-fourths of the patients had been hospitalized at least once because of HF before the enrollment (20/27, 74%); 14 patients had 1, 2 patients had 2, and 4 patients had 3 or more previous HF hospitalizations. In the total study population, there was no significant interval change in laboratory and functional outcome variables after 12 weeks of ICT-based telehealth program. In patients with good adherence to ICT-based telehealth program, there was a significant improvement in the mean uNa (103.1 to 78.1; P=.01) but not in those without (85.4 to 96.9; P=.49). Similarly, a marginal improvement in MLHFQ scores was only observed in patients with good adherence (27.5 to 21.4; P=.08) but not in their counterparts (19.0 to 19.7; P=.73). The mean 6-min walk distance and NT-proBNP were not significantly increased in patients regardless of their adherence. Short-term application of ICT-based telehealth program with voice recognition technology showed the potential to improve uNa values and MLHFQ scores in HF patients, suggesting that better control of sodium intake and greater quality of life can be achieved by this program. ©Heesun Lee, Jun-Bean Park, Sae Won Choi, Yeonyee E Yoon, Hyo Eun Park, Sang Eun Lee, Seung-Pyo Lee, Hyung-Kwan Kim, Hyun-Jai Cho, Su-Yeon Choi, Hae-Young Lee, Jonghyuk Choi, Young-Joon Lee, Yong-Jin Kim, Goo-Yeong Cho, Jinwook Choi, Dae-Won Sohn. Originally published in JMIR Mhealth and Uhealth (http://mhealth.jmir.org), 02.10.2017.

Species differences in the disposition and metabolism of nalidixic acid.

PubMed

Nomeir, A A; Markham, P; Burka, L T; Griffin, R J; Ghanayem, B I

1996-10-01

Nalidixic acid (NA) is an antimicrobial drug that has been used to treat urinary tract infections. A study of NA by the National Toxicology Program indicated that chronic administration in the diet at doses equivalent to 82 and 175 mg/kg/day for rats, and 175 and 475 mg/kg/day for mice resulted in neoplastic lesions in the preputial and clitoral glands of male and female Fischer 344 rats, respectively, but not in male and female B6C3F1 mice. Our study was designed to evaluate the metabolic basis of this species and tissue-dependent carcinogenicity. [14C]NA was administered by oral gavage as a suspension in corn oil at doses of 20, 200 or 500 mg/kg. Based on urinary excretion data, at least 35 to 46 and 57 to 79% of dose was absorbed from the gastrointestinal tracts of mice and rats, respectively. NA-derived radioactivity was excreted primarily in urine and feces. The urinary and fecal metabolite profiles were species dependent. At 72 hr after administration, in both genders of rats and mice, the highest concentrations of radioactivity were observed in the liver, and the lowest were in the brain and adipose tissue. The preputial and clitoral glands of male and female rats, respectively, contained consistently and substantially higher concentrations of radioactivity compared to all other tissues, with the exception of liver. In mice, the levels of radioactivity in these tissues were near or below quantifiable levels. The metabolism and disposition characteristics of NA were linear in male and female mice over a dose range of 20 to 500 mg/kg: in rats, they were dose dependent. Results of this study suggest that the species- and tissue-dependent differences in carcinogenicity of NA were associated with differences in metabolism and disposition between the two species.

Effects of diazinon on adaptation to sea-water by the endangered Persian sturgeon, Acipenser persicus, fingerlings.

PubMed

Hajirezaee, Saeed; Mirvaghefi, Ali Reza; Farahmand, Hamid; Agh, Naser

2016-11-01

To replenish the depleting populations of sturgeon fishes especially Persian sturgeon, Acipenser persicus in the Caspian Sea, millions of Persian sturgeon fingerlings are farmed through artificial propagation and released into the Iranian river estuaries annually. Fish osmoregulation is a vital physiological process that can be affected during the release. Many Iranian river estuaries are under the influence of pesticides originating from farming activities that may affect osmoregulation. In this study, Persian sturgeon fingerlings were exposed to sublethal concentrations (0, 0.18, 0.54, 0.9mgL(-)(1)) of diazinon for 96h (short-term trial) and 12 days (long-term trial) in fresh water (FW) and then fish were exposed in brackish water (BW) for 24h. After 96h and 12 days of exposure in FW, the lower levels of plasma triidothyronine (T3), thyroxine (T4), Na(+), Cl(-), K(+), gill Na(+)/K(+)- ATPase activity and number of chloride cells were observed in exposed fish (0.54 and 0.9mgL(-)(1) diazinon) compared to control group and 0.18mgL(-)(1) diazinon treatment. Also, higher levels of plasma cortisol (except 0.18mgL(-)(1) diazinon treatment in long-term trial) were observed in diazinon exposed fish compared to control group. However, gill Na(+)/K(+)-ATPase activity and the number of chloride cells were higher in fingerlings exposed to diazinon compared than control. When fish were exposed in BW for 24h, the following changes occurred: (a) in short-term trial: increases in cortisol and Cl(-) levels (0.54mgL(-)(1) diazinon ), Na(+) (0.9mgL(-)(1) diazinon ) and gill Na(+)/K(+)-ATPase activity (0.18mgL(-)(1) diazinon ). In control group, cortisol, T4, Na(+), gill Na(+)/K(+)-ATPase activity and the number of chloride cells increased significantly. (b) In long-term trial: increases in K(+) levels in fish exposed to 0.9mgL(-)(1) diazinon, Na+ in all diazinon concentrations and decreases in chloride cells number in fish exposed to 0.18mgL(-)(1) diazinon. In control group, significant increases were observed in cortisol, T3, Na(+) and chloride cells number. Finally, gill showed many histopathological damages during exposure in FW and BW. Our results suggest that the contamination of river estuaries with diazinon may alter the osmoregulation ability of released Persian sturgeon fingerlings, which could lead to a failure in their restocking program in the Caspian Sea. Copyright © 2016 Elsevier Inc. All rights reserved.

The CNO Bi-cycle in the Open Cluster NGC 752

NASA Astrophysics Data System (ADS)

Hawkins, Keith; Schuler, S.; King, J.; The, L.

2011-01-01

The CNO bi-cycle is the primary energy source for main sequence stars more massive than the sun. To test our understanding of stellar evolution models using the CNO bi-cycle, we have undertaken light-element (CNO) abundance analysis of three main sequence dwarf stars and three red giant stars in the open cluster NGC 752 utilizing high resolution (R 50,000) spectroscopy from the Keck Observatory. Preliminary results indicate, as expected, there is a depletion of carbon in the giants relative to the dwarfs. Additional analysis is needed to determine if the amount of depletion is in line with model predictions, as seen in the Hyades open cluster. Oxygen abundances are derived from the high-excitation O I triplet, and there is a 0.19 dex offset in the [O/H] abundances between the giants and dwarfs which may be explained by non-local thermodynamic equilibrium (NLTE), although further analysis is needed to verify this. The standard procedure for spectroscopically determining stellar parameters used here allows for a measurement of the cluster metallicity, [Fe/H] = 0.04 ± 0.02. In addition to the Fe abundances we have determined Na, Mg, and Al abundances to determine the status of other nucleosynthesis processes. The Na, Mg and Al abundances of the giants are enhanced relative to the dwarfs, which is consistent with similar findings in giants of other open clusters. Support for K. Hawkins was provided by the NOAO/KPNO Research Experiences for Undergraduates (REU) Program which is funded by the National Science Foundation Research Experiences for Undergraduates Program and the Department of Defense ASSURE program through Scientific Program Order No. 13 (AST-0754223) of the Cooperative Agreement No. AST-0132798 between the Association of Universities for Research in Astronomy (AURA) and the NSF.

DEVELOPMENT OF METRICS FOR TECHNICAL PRODUCTION: QUALIS BOOKS AND BOOK CHAPTERS.

PubMed

Ribas-Filho, Jurandir Marcondes; Malafaia, Osvaldo; Czeczko, Nicolau Gregori; Ribas, Carmen A P Marcondes; Nassif, Paulo Afonso Nunes

2015-01-01

To propose metrics to qualify the publication in books and chapters, and from there, establish guidance for the evaluation of the Medicine III programs. Analysis of some of the 2013 area documents focusing this issue. Were analyzed the following areas: Computer Science; Biotechnology; Biological Sciences I; Public Health; Medicine I. Except for the Medicine I, which has not adopted the metric for books and chapters, all other programs established metrics within the intellectual production, although with unequal percentages. It´s desirable to include metrics for books and book chapters in the intellectual production of post-graduate programs in Area Document with percentage-value of 5% in publications of Medicine III programs. Propor a métrica para qualificar a produção veiculada através de livros e capítulos e, a partir daí, estabelecer orientação para a avaliação dos programas de pós-graduação da Medicina III. Análise dos documentos de área de 2013 dos programas de pós-graduação senso estrito das áreas: Ciência da Computação; Biotecnologia; Ciências Biológicas I; Saúde Coletiva; Medicina I. Excetuando-se o programa da Medicina I, que não adotou a métrica para classificação de livros e capítulos, todos os demais estabeleceram-na dentro da sua produção intelectual, embora com percentuais desiguais. É desejável inserir a métrica de livros e capitulos de livros na produção intelectual do Documento de Área dos programas, ortorgando a ela percentual de 5% das publicações qualificadas dos programas da Medicina III.

Dynamics of pH modification of an acidic protein bait used for tropical fruit flies (Diptera: Tephritidae).

PubMed

Heath, Robert R; Vazquez, Aime; Schnell, Elena Q; Villareal, Janett; Kendra, Paul E; Epsky, Nancy D

2009-12-01

Several species of Anastrepha and Bactrocera fruit flies (Diptera: Tephritidae) are captured in traps baited with the protein bait NuLure combined with borax (sodium tetraborate decahydrate) in an aqueous solution, typically 9% NuLure (vol:vol) with 3% borax (wt:vol). NuLure is an acid hydrolysate of corn and has an acidic pH. Addition of borax makes the solution more alkaline, and increase in alkalinity results in increase of ammonia release from the bait solution. This is a very dynamic system, with resultant pH affected by factors such as the amount of borax added, the pH of the water used for preparation, the age of the bait solution, and the development of microbial growth. Problems with borax include amount needed to increase alkalinity of NuLure solutions, which creates difficulties in disposing of spent bait in fruit fly trapping programs. Therefore, research was conducted to evaluate NaOH as an alternative method to increase alkalinity of NuLure solutions. Laboratory experiments compared effect of NaOH versus borax for pH modification on changes in pH and ammonia content of NuLure solutions over time. Although NuLure/NaOH solutions could be adjusted to a more alkaline pH than NuLure/borax solutions, borax plays a critical role in pH stability over time. However, the pH of NuLure/NaOH is stabilized when propylene glycol (10% vol:vol) was used to prepare the bait solution. The use of NaOH can provide an alternative to the use of borax to increase bait solution alkalinity.

A mathematical model of electrolyte and fluid transport across corneal endothelium.

PubMed

Fischbarg, J; Diecke, F P J

2005-01-01

To predict the behavior of a transporting epithelium by intuitive means can be complex and frustrating. As the number of parameters to be considered increases beyond a few, the task can be termed impossible. The alternative is to model epithelial behavior by mathematical means. For that to be feasible, it has been presumed that a large amount of experimental information is required, so as to be able to use known values for the majority of kinetic parameters. However, in the present case, we are modeling corneal endothelial behavior beginning with experimental values for only five of eleven parameters. The remaining parameter values are calculated assuming cellular steady state and using algebraic software. With that as base, as in preceding treatments but with a distribution of channels/transporters suited to the endothelium, temporal cell and tissue behavior are computed by a program written in Basic that monitors changes in chemical and electrical driving forces across cell membranes and the paracellular pathway. We find that the program reproduces quite well the behaviors experimentally observed for the translayer electrical potential difference and rate of fluid transport, (a) in the steady state, (b) after perturbations by changes in ambient conditions HCO3-, Na+, and Cl- concentrations), and (c) after challenge by inhibitors (ouabain, DIDS, Na+- and Cl(-)-channel inhibitors). In addition, we have used the program to compare predictions of translayer fluid transport by two competing theories, electro-osmosis and local osmosis. Only predictions using electro-osmosis fit all the experimental data.

Closed-Cycle Engine Program Used to Study Brayton Power Conversion

NASA Technical Reports Server (NTRS)

Johnson, Paul K.

2005-01-01

One form of power conversion under consideration in NASA Glenn Research Center's Thermal Energy Conversion Branch is the closed-Brayton-cycle engine. In the tens-of-kilowatts to multimegawatt class, the Brayton engine lends itself to potential space nuclear power applications such as electric propulsion or surface power. The Thermal Energy Conversion Branch has most recently concentrated its Brayton studies on electric propulsion for Prometheus. One piece of software used for evaluating such designs over a limited tradeoff space has been the Closed Cycle Engine Program (CCEP). The CCEP originated in the mid-1980s from a Fortran aircraft engine code known as the Navy/NASA Engine Program (NNEP). Components such as a solar collector, heat exchangers, ducting, a pumped-loop radiator, a nuclear heat source, and radial turbomachinery were added to NNEP, transforming it into a high-fidelity design and performance tool for closed-Brayton-cycle power conversion and heat rejection. CCEP was used in the 1990s in conjunction with the Solar Dynamic Ground Test Demonstration conducted at Glenn. Over the past year, updates were made to CCEP to adapt it for an electric propulsion application. The pumped-loop radiator coolant can now be n-heptane, water, or sodium-potassium (NaK); liquid-metal pump design tables were added to accommodate the NaK fluid. For the reactor and shield, a user can now elect to calculate a higher fidelity mass estimate. In addition, helium-xenon working-fluid properties were recalculated and updated.

U.S. Additional Protocol Outreach Program-Tabletop Exercises to Implement the AP.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Langner, D. C.; Thomas, K. E.; Smith, M. K.

2005-01-01

The Office of International Regimes and Agreement (NA-243) is the lead office in the Department of Energy (DOE) to assist DOE and National Nuclear Security Administration (NNSA) sites in the preparation of providing declarations on relevant civilian, nuclear fuel cycle-related research and development activities to the International Atomic Energy Agency (IAEA). This is in accordance to the implementation of the ''Protocol Additional to the AGreement between the United STates and the International Atomic Energy Agency for the Applications of Safeguards in the United States. In preparation for entry-into-force, NA-243 conducted two tabletop exercises under the Additional Protocol Outreach Program. Themore » first one, held in May 2004 at Los Alamos National Laboratory, focused on the factors important to protect national security assets and intellectual property. The other, held in August 2004 at the Idaho National Laboratory explored the level of detail or granularity for reporting declarable activities. Both tabletops invited participants from the national laboratories and DOE/NNSA organizations. Discussions were based around the process to identify potential declarable activities relating to the nuclear fuel cycle-related R and D projects from the Advanced Fuel Cycle Initiative program. The two tabletop exercises provided recommendations and conclusions that would be helpful to other DOE/NNSA locations for preparing for and reporting relevant and concise information to the IAEA under the Additional Protocol. This paper provides details on the events, discussions, observations, and lessons learned from both the LANL and INL tabletop exercises.« less

Memory T and memory B cells share a transcriptional program of self-renewal with long-term hematopoietic stem cells

PubMed Central

Luckey, Chance John; Bhattacharya, Deepta; Goldrath, Ananda W.; Weissman, Irving L.; Benoist, Christophe; Mathis, Diane

2006-01-01

The only cells of the hematopoietic system that undergo self-renewal for the lifetime of the organism are long-term hematopoietic stem cells and memory T and B cells. To determine whether there is a shared transcriptional program among these self-renewing populations, we first compared the gene-expression profiles of naïve, effector and memory CD8+ T cells with those of long-term hematopoietic stem cells, short-term hematopoietic stem cells, and lineage-committed progenitors. Transcripts augmented in memory CD8+ T cells relative to naïve and effector T cells were selectively enriched in long-term hematopoietic stem cells and were progressively lost in their short-term and lineage-committed counterparts. Furthermore, transcripts selectively decreased in memory CD8+ T cells were selectively down-regulated in long-term hematopoietic stem cells and progressively increased with differentiation. To confirm that this pattern was a general property of immunologic memory, we turned to independently generated gene expression profiles of memory, naïve, germinal center, and plasma B cells. Once again, memory-enriched and -depleted transcripts were also appropriately augmented and diminished in long-term hematopoietic stem cells, and their expression correlated with progressive loss of self-renewal function. Thus, there appears to be a common signature of both up- and down-regulated transcripts shared between memory T cells, memory B cells, and long-term hematopoietic stem cells. This signature was not consistently enriched in neural or embryonic stem cell populations and, therefore, appears to be restricted to the hematopoeitic system. These observations provide evidence that the shared phenotype of self-renewal in the hematopoietic system is linked at the molecular level. PMID:16492737

Retention of antiretroviral naïve patients registered in HIV care in a program clinic in Pune, India

PubMed Central

Ghate, Manisha V.; Zirpe, Sunil S.; Gurav, Nilam P.; Rewari, Bharat B.; Gangakhedkar, Raman R.; Paranjape, Ramesh S.

2014-01-01

Background: Retention in HIV care ensures delivery of services like secondary prevention, timely initiation of treatment, support, and care on a regular basis. The data on retention in pre antiretroviral therapy (ART) care in India is scanty. Materials and Methods: Antiretroviral naïve HIV-infected adult patients registered between January 2011 and March 2012 in HIV care (pre-ART) were included in the study. The follow-up procedures were done as per the national guidelines. Patients who did not report to the clinic for 1 year were considered as pre-ART lost to follow-up (pre-ART LFU). They were contacted either telephonically or by home visits. Logistic regression analysis was done to find out factors associated with pre-ART loss to follow-up. Results: A total of 689 antiretroviral naïve adult patients were registered in the HIV care. Fourteen (2%) patients died and 76 (11%) were LFU till March 2013. The multivariate analysis showed that baseline CD4 count >350 cells/mm3 (P < 0.01) and illiteracy (P = 0.044) were significantly associated with LFU. Of the total pre-ART LFUs, 35 (46.1%) informed that they would visit the clinic at their convenient time. NGOs that referred 16 female sex workers (FSWs) who were LFU (21.1%) informed that they would make efforts to refer them to the clinic. Conclusion: Higher CD4 count and illiteracy were significantly associated with lower retention in pre-ART care. Developing effective “retention package” for patients and strengthening linkage strategies between key sub-population such as FSWs and ART programming will help to plug the leaky cascade in HIV care. PMID:26396447

Single-arm, open label study of pemetrexed plus cisplatin in chemotherapy naïve patients with malignant pleural mesothelioma: outcomes of an expanded access program.

PubMed

Obasaju, Coleman K; Ye, Zhishen; Wozniak, Antoinette J; Belani, Chandra P; Keohan, Mary-Louise; Ross, Helen J; Polikoff, Jonathan A; Mintzer, David M; Monberg, Matthew J; Jänne, Pasi A

2007-02-01

An expanded access program (EAP) provided patient access to pemetrexed prior to its commercial availability. The current report consists of US patients in the EAP who had chemotherapy naïve pleural mesothelioma. Eligible patients had a histologic or cytologic diagnosis of malignant mesothelioma that was not amenable to curative treatment with surgery. Study treatment consisted of pemetrexed 500mg/m(2) in combination with cisplatin 75mg/m(2) once every 21 days. Vitamin B12, folic acid, and dexamethasone were administered as prophylaxis. Serious adverse events (SAEs) were reported by investigators and compiled in a pharmacovigilance database for all patients enrolled in the EAP. Of 1056 patients receiving at least one dose of pemetrexed in the EAP, 728 had chemotherapy naïve pleural mesothelioma. Median age of this group was 70 years (range 23-89 years) and 84% were male. Among 615 patients, overall response rate was 20.5%, including 12 complete responses (2.0%) and 114 partial responses (18.5%). An additional 290 patients (47.2%) had stable disease. Median survival for all 728 patients was 10.8 months (95% CI=9.8, 12.3; 60.3% censorship) and 1 year survival was 45.4%. The most commonly reported SAEs in the overall EAP irrespective of causality were dehydration (7.2%), nausea (5.2%), vomiting (4.9%), dyspnea (3.8%), and pulmonary embolism (2.4%). In this large cohort, 67.7% of patients treated with first-line chemotherapy experienced a response or stable disease. Survival time and toxicity from this EAP were promising for this difficult-to-treat disease.

Kawachin na ri kitzij-kipixab' Qanan Qatat--Florezcan las palabras de los hombres de maiz (The Blossoming of Our Ancestors' Words). [CD-ROM].

ERIC Educational Resources Information Center

Academy for Educational Development, Washington, DC.

This CD-ROM is part of an interactive and dynamic multimedia package of information and games for learning K'iche' and Ixil. This CD-ROM contains selected radio programs for preschool students, scripted from the four storybooks created by Project "Enlace Quiche." It includes stories in K'iche', Ixil, and Spanish. (VWL)

Equalization in Aeronautical Telemetry Using Multiple Antennas

DTIC Science & Technology

2014-04-01

Multiple Antennas April 2014 DISTRIBUTION STATEMENT A. Approved for public release: distribution unlimited. Test Resource Management Center...Telemetry Using Multiple Antennas 5a. CONTRACT NUMBER: W900KK-13-C- 0026 5b. GRANT NUMBER: N/A 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Michael...employing two transmit antennas and as a method for exploiting partial channel state information by the transmitter. The generalization involves

JPRS Report, Science & Technology Europe

DTIC Science & Technology

1988-05-10

given environment essentially depends on three parameters ; these are: • the adhesion between the adhesive and the supports; • the cohesion of the...durability/CND J Electric current under high field/Tensile test at 4 degrees K I Synthetic hydroxyapatite /behavior under friction and wear GB NaCl, s...French programs GB Inventory of accelerated test procedures, correlation among parameters FC Influence of experimental parameters 8615 JPRS-EST-88

Secure Location Provenance for Mobile Devices

DTIC Science & Technology

2015-07-01

SECURE LOCATION PROVENANCE FOR MOBILE DEVICES UNIVERSITY OF ALABAMA AT BIRMINGHAM JULY 2015 FINAL TECHNICAL REPORT...PROVENANCE FOR MOBILE DEVICES 5a. CONTRACT NUMBER FA8750-12-2-0254 5b. GRANT NUMBER N/A 5c. PROGRAM ELEMENT NUMBER 69220K 6. AUTHOR(S) Ragib Hasan...based services allow mobile device users to access various services based on the users’ current physical location information. Path-critical applications

Sensitivity Analysis for Multidisciplinary Systems (SAMS)

DTIC Science & Technology

2016-12-01

support both mode-based structural representations and time-dependent, nonlinear finite element structural dynamics. This interim report describes...Adaptation, & Sensitivity Toolkit • Elasticity, heat transfer, & compressible flow • Adjoint solver for sensitivity analysis • High-order finite elements ...PROGRAM ELEMENT NUMBER 62201F 6. AUTHOR(S) Richard D. Snyder 5d. PROJECT NUMBER 2401 5e. TASK NUMBER N/A 5f. WORK UNIT NUMBER Q1FS 7

Informe Especial: O Ensino e a Promocao do Portugues na Romenia (Special Report: The Teaching and Promotion of Portuguese in Romania).

ERIC Educational Resources Information Center

Ploae-Hanganu, Mariana

1996-01-01

This article reflects the most significant advances made in the teaching and promotion of Portuguese in Romania in the past 20 years. The Portuguese program at the University of Bucharest is described as are special courses given in commemoration of landmark dates in Portuguese history and special events celebrating Portuguese history and culture.…

Increasing Capacity & Changing the Culture: Volunteer Management in Law Enforcement

DTIC Science & Technology

2009-03-01

6. AUTHOR(S) Donna Cayson 5. FUNDING NUMBERS 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Naval Postgraduate School Monterey, CA 93943...5000 8. PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING /MONITORING AGENCY NAME(S) AND ADDRESS(ES) N/A 10. SPONSORING/MONITORING...mission performance in a law enforcement agency’s volunteer program? Furthermore, the research will address the role of volunteers in law enforcement

Joint Strike Figher Acquisition: Mature Critical Technologies Needed to Reduce Risks

DTIC Science & Technology

2001-10-01

Reduce Risks GAO-02-39 Report Documentation Page Report Date 00OCT2001 Report Type N/A Dates Covered (from... to) - Title and Subtitle JOINT STRIKE...FIGHTER ACQUISITION: Mature Critical Technologies Needed to Reduce Risks Contract Number Grant Number Program Element Number Author(s) Project...1Joint Strike Fighter Acquisition: Development Schedule Should Be Changed to Reduce Risks (GAO/T-NSIAD-00-132

Cargo Movement Operations System (CMOS) System Segment Design Document (Draft) Increment II

DTIC Science & Technology

1990-05-02

and are arranged in page number order. RATIONALE: N/A CMOS PMO ACCEPTS COMMENT: YES [ ] NO [ ] ERCI ACCEPTS COMMENT: YES [ ] NO [ ] COMMENT DISPOSITION...NO [ ] ERCI ACCEPTS COMMENT: YES [ ] NO [ ] COMMENT DISPOSITION: COMMENT STATUS: OPEN [ ] CLOSED [ ] ORIGINATOR CONTROL NUMBER: SSDD-0003 PROGRAM...CMOS. CMOS PMO ACCEPTS COMMENT: YES [ ] NO [ ] ERCI ACCEPTS COMMENT: YES [ ] NO [ ] COMMENT DISPOSITION: COMMENT STATUS: OPEN [ ] CLOSED [ 3 ORIGINATOR

Cargo Movement Operations System (CMOS) Computer System Operator’s Manual. Draft

DTIC Science & Technology

1990-06-27

are arranged in page number order. RATIONALE: N/A CMOS PMO ACCEPTS COMMENT: YES [ ] NO [ ] ERCI ACCEPTS COMMENT: YES [ ] NO [ ] COMMENT DISPOSITION...ACCEPTS COMMENT: YES [ ] NO [ ] COMMENT DISPOSITION: COMMEN7 STATUS: OPEN [ ] CLOSED [ ] ORIGINATOR CONTROL NUMBER: CSOM-0003 PROGRAM OFFICE CONTROL...ACCEPTS COMMENT: YES [ ] NO ( 3 ERCI ACCEPTS COMMENT: YES [ ] NO [ ] COMMENT DISPOSITION: COMMENT STATUS: OPEN [ ] CLOSED [ 3 ORIGINATOR CONTROL NUMBER

Arctic Ice Studies

DTIC Science & Technology

1993-02-01

Aeronautics and Space Administration; DMSP: Defense Meteorological Satellit= innovative helicopter survey for ambient Program; AVHRR: Advanced Very High...a" aA z’•Lae Na g 419" .aso ." -I Nas"o Te a ’ b 0 York A4CJ ’ crk A19. YCrk t•nrtid 0 .436 b = -. 49cr9k Trott *._-. 3 - -. Now A19. No~v, AtC. Nowv

Wireless Sensor Network With Geolocation

DTIC Science & Technology

2006-11-01

WIRELESS SENSOR NETWORK WITH GEOLOCATION James Silverstrim and Roderick Passmore Innovative Wireless Technologies Forest, VA 24551 Dr...TYPE N/A 3. DATES COVERED - 4. TITLE AND SUBTITLE Wireless Sensor Network With Geolocation 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM...Locationing in distributed ad-hoc wireless sensor networks ”, IEEE ICASSP, May 2001. D. W. Hanson, Fundamentals of Two-Way Time Transfer by Satellite

Generic and Automated Runtime Program Repair

DTIC Science & Technology

2012-09-01

other person or corporation; or convey any rights or permission to manufacture, use, or sell any patented invention that may relate to them... PERSON PATRICK M. HURLEY a. REPORT U b. ABSTRACT U c. THIS PAGE U 19b. TELEPONE NUMBER (Include area code) N/A Standard Form 298...Public Release; Distribution Unlimited. 2. Introduction Software bugs are ubiquitous, and fixing them remains a difficult, time- consuming , and manual

Failure Criterion For Isotropic Time Dependent Materials Which Accounts for Multi-Axial Loading

NASA Technical Reports Server (NTRS)

Richardson, D. E.; Anderson, G. L.; Macon, D. J.

2003-01-01

The Space Shuttle's Reusable Solid Rocket Motor (RSRM) nozzle program has recently conducted testing to characterize the effects of multi-axial loading, temperature and time on the failure characteristics of TIGA321, EA913NA, EA946 (three filled epoxy adhesives). From the test data a "Multi-Axial, Temperature, and Time Dependent" or MATT failure criterion was developed. It is shown that this criterion simplifies, for constant load and constant load rate conditions, into a form that can be easily used for stress analysis. Failure for TIGA321 and EA913NA are characterized below their glass transition temperature. Failure for EA946 is characterized for conditions that pass through its glass transition. The MATT failure criterion is shown to be accurate for a wide range of conditions for these adhesives.

An Exploratory Research and Development Program Leading to Specifications for Aviation Turbine Fuel from Whole Crude Shale Oil. Part V.

DTIC Science & Technology

1982-03-01

Velocity LP Linear Program LP Sep Low Pressure Separator Mo Molybdenum N2 Nitrogen Gas NA Not Available NH3 Ammonia Gas xiv LIST OF SYMBOLS AND...part, is present as heterocyclic compounds. It is reduced to ammonia and re- moved as such or the heterocyclic compounds are saturated to basic nitro...the carbon-nitrogen bond and then removing the nitrogen from the amine as ammonia .(4) -2- ------- C5HI 1 NH2 +H2 -5l H . - 2C5H2 + NH3 N N H It can be

n/a

NASA Image and Video Library

1962-03-08

The members of the House Committee on Science and Astronautics visited the Marshall Space Flight Center (MSFC) on March 9, 1962 to gather firsthand information of the nation's space exploration program. The congressional group was composed of members of the Subcommittee on Manned Space Flight. They were briefed on MSFC's manned space efforts earlier in the day and then inspected mockups of the Saturn I Workshop and the Apollo Telescope Mount, two projects developed by MSFC for the post-Apollo program. Pictured left-to-right are Dieter Grau, MSFC; Konrad Dannenberg, MSFC; James G. Fulton, Republican representative for Pennsylvania; Joe Waggoner, Democratic representative for Louisiana; and Dr. Wernher von Braun, Director of MSFC.

Changing the Impact of Nursing Assistants' Education in Seniors' Care: the Living Classroom in Long-Term Care.

PubMed

Boscart, Veronique M; d'Avernas, Josie; Brown, Paul; Raasok, Marlene

2017-03-01

Evidence-informed care to support seniors is based on strong knowledge and skills of nursing assistants (NAs). Currently, there are insufficient NAs in the workforce, and new graduates are not always attracted to nursing home (NH) sectors because of limited exposure and lack of confidence. Innovative collaborative approaches are required to prepare NAs to care for seniors. A 2009 collaboration between a NH group and a community college resulted in the Living Classroom (LC), a collaborative approach to integrated learning where NA students, college faculty, NH teams, residents, and families engage in a culture of learning. This approach situates the learner within the NH where knowledge, team dynamics, relationships, behaviours, and inter-professional (IP) practice are modelled. As of today, over 300 NA students have successfully completed this program. NA students indicate high satisfaction with the LC and have an increased intention to seek employment in NHs. Faculty, NH teams, residents, and families have increased positive beliefs towards educating students in a NH. The LC is an effective learning approach with a positive and high impact learning experience for all. The LC is instrumental in contributing to a capable workforce caring for seniors.

Preparation and photocatalytic activities of 3D flower-like CuO nanostructures

NASA Astrophysics Data System (ADS)

Qingfei, Fan; Qi, Lan; Meili, Zhang; Ximei, Fan; Zuowan, Zhou; Chaoliang, Zhang

2016-08-01

Hierarchical 3D flower-like CuO nanostructures on the Cu substrates were synthesized by a wet chemical method and subsequent heat treatment. The synthesis, structure and morphologies of obtained samples under different concentrations of Na2S2O3 were investigated in detail and the possible growth mechanisms of the 3D flower-like CuO nanostructures were discussed. Na2S2O3 plays a key role in the generation of the 3D flower-like CuO nanostructures. When the concentration of Na2S2O3 is more than 0.4 mol/L, the 3D flower-like CuO nanostructures can be prepared on the Cu foils. The photocatalytic performances were studied by analyzing the degradation of methyl orange (MO) in aqueous solution in the presence of hydroxide water (H2O2). The 3D flower-like CuO nanostructures exhibit higher photocatalytic activity (96.2% degradation rate) than commercial CuO particles (36.3% degradation rate). The origin of the higher photocatalytic activity of the 3D flower-like CuO nanostructures was also discussed. Project supported by the High-Tech Research and Development Program of China (No. 2009AA03Z427).

40 CFR Table I-4 to Subpart I - Table I-4 to Subpart I of Part 98-Default Emission Factors (1-Uij) for Gas Utilization Rates (Uij...

Code of Federal Regulations, 2012 CFR

2012-07-01

... NA NA NA NA NA NA NA NA NA NA Chamber Cleaning In situ plasma cleaning: 1-Ui NA NA NA NA NA NA 0.23... NA NA NA NA NA In Situ Thermal Cleaning: 1-Ui NA NA NA NA NA NA 0.28 NA NA NA NA BCF4 NA NA NA NA NA...

An efficient and reproducible protocol for the production of salt tolerant transgenic wheat plants expressing the Arabidopsis AtNHX1 gene.

PubMed

Moghaieb, Reda E A; Sharaf, Ahmed N; Soliman, Mohamed H; El-Arabi, Nagwa I; Momtaz, Osama A

2014-01-01

We present an efficient method for the production of transgenic salt tolerant hexaploid wheat plants expressing the Arabidopsis AtNHX1 gene. Wheat mature zygotic embryos were isolated from two hexaploid bread wheat (Triticum aestivum) cultivars (namely: Gemmeiza 9 and Gemmeiza 10) and were transformed with the A. tumefaciens LBA4404 harboring the pBI-121 vector containing the AtNHX1 gene. Transgenic wheat lines that express the gus intron was obtained and used as control. The results confirmed that npt-II gene could be transmitted and expressed in the T2 following 3:1 Mendelian segregation while the control plant couldn't. The data indicate that, the AtNHX1 gene was integrated in a stable manner into the wheat genome and the corresponding transcripts were expressed. The transformation efficiency was 5.7 and 7.5% for cultivars Gemmeiza 10 and Gemmeiza 9, respectively. A greenhouse experiment was conducted to investigate the effect of AtNHX1 gene in wheat salt tolerance. The transgenic wheat lines could maintain high growth rate under salt stress condition (350 mM NaCl) while the control plant couldn't. The results confirmed that Na(+)/H(+) antiporter gene AtNHX1 increased salt tolerance by increasing Na(+) accumulation and keeping K+/Na(+) balance. Thus, transgenic plants showed high tolerance to salt stress and can be considered as a new genetic resource in breeding programs.

Performance analysis of a potassium-base AMTEC cell

DOE Office of Scientific and Technical Information (OSTI.GOV)

Huang, C.; Hendricks, T.J.; Hunt, T.K.

1998-07-01

Sodium-BASE Alkali-Metal-Thermal-to-Electric-Conversion (AMTEC) cells have been receiving increased attention and funding from the Department of Energy, NASA and the United States Air Force. Recently, sodium-BASE (Na-BASE) AMTEC cells were selected for the Advanced Radioisotope Power System (ARPS) program for the next generation of deep-space missions and spacecraft. Potassium-BASE (K-BASE) AMTEC cells have not received as much attention to date, even though the vapor pressure of potassium is higher than that of sodium at the same temperature. So that, K-BASE AMTEC cells with potentially higher open circuit voltage and higher power output than Na-BASE AMTEC cells are possible. Because the surfacemore » tension of potassium is about half of the surface tension of sodium at the same temperature, the artery and evaporator design in a potassium AMTEC cell has much more challenging pore size requirements than designs using sodium. This paper uses a flexible thermal/fluid/electrical model to predict the performance of a K-BASE AMTEC cell. Pore sizes in the artery of K-BASE AMTEC cells must be smaller by an order of magnitude than in Na-BASE AMTEC cells. The performance of a K-BASE AMTEC cell was higher than a Na-BASE AMTEC cell at low voltages/high currents. K-BASE AMTEC cells also have the potential of much better electrode performance, thereby creating another avenue for potentially better performance in K-BASE AMTEC cells.« less

40 CFR Table I-4 to Subpart I of... - Default Emission Factors (1-Uij) for Gas Utilization Rates (Uij) and By-Product Formation Rates...

Code of Federal Regulations, 2013 CFR

2013-07-01

... C5F8 C4F8O Plasma Etching 1-Ui 0.80 0.80 0.48 0.14 NA 0.29 0.32 0.37 0.09 NA NA BCF4 NA NA 0.0018 0... NA NA NA NA NA Chamber Cleaning In situ plasma cleaning: 1-Ui NA NA NA NA NA NA 0.23 NA NA NA NA BCF4... NA NA NA NA NA Remote Plasma Cleaning: 1-Ui NA NA NA NA 0.063 NA 0.018 NA NA NA NA BCF4 NA NA NA NA...

40 CFR Table I-3 to Subpart I of... - Default Emission Factors (1-Uij) for Gas Utilization Rates (Uij) and By-Product Formation Rates...

Code of Federal Regulations, 2012 CFR

2012-07-01

... C4F6 C5F8 C4F8O Plasma Etching 1-Ui 0.69 0.56 0.38 0.093 NA 0.25 0.038 0.20 0.14 NA NA BCF4 NA 0.23 0... NA NA NA NA NA NA NA Chamber Cleaning In situ plasma cleaning: 1-Ui 0.92 0.55 NA NA 0.40 0.10 0.18 NA... BC3F8 NA NA NA NA NA NA NA NA NA NA NA Remote plasma cleaning: 1-Ui NA NA NA NA NA NA 0.018 NA NA NA NA...

40 CFR Table I-3 to Subpart I of... - Default Emission Factors (1-Uij) for Gas Utilization Rates (Uij) and By-Product Formation Rates...

Code of Federal Regulations, 2013 CFR

2013-07-01

... C4F6 C5F8 C4F8O Plasma Etching 1-Ui 0.69 0.56 0.38 0.093 NA 0.25 0.038 0.20 0.14 NA NA BCF4 NA 0.23 0... NA NA NA NA NA NA NA Chamber Cleaning In situ plasma cleaning: 1-Ui 0.92 0.55 NA NA 0.40 0.10 0.18 NA... BC3F8 NA NA NA NA NA NA NA NA NA NA NA Remote plasma cleaning: 1-Ui NA NA NA NA NA NA 0.018 NA NA NA NA...

Acupuncture for Disturbed Sleep in Veterans with Post Traumatic Stress Disorder

DTIC Science & Technology

2014-09-25

Diego, School of Nursing , 5998 Alcala Park, San Diego, CA 92110 N/A 9. SPONSORING / MONITORING AGENCY NAME(S...AND ADDRESS(ES) 10. SPONSOR/MONITOR’S ACRONYM(S) TriService Nursing Research TSNRP Program, 4301 Jones Bridge RD Bethesda, MD 20814 11...dysfunction components of the PSQI (p = 0.003, P = 0.004). Implications for Military Nursing : Military nurses can practice AA, which has expanded non

Recommended Processes and Best Practices for Nondestructive Inspection (NDI) of Safety-Of-Flight Structures

DTIC Science & Technology

2008-10-01

Brausch, Lawrence Butkus, David Campbell, Tommy Mullis, and Michael Paulk Materials Integrity Branch System Support Division OCTOBER...PROGRAM ELEMENT NUMBER N/A 6. AUTHOR(S) John Brausch and Dr. Lawrence Butkus (AFRL/RXSA) David Campbell (76 MXSS/MXDEBB) Tommy Mullis (WRALC... David Forsyth, Texas Research Institute Austin, Inc. Dr. Matt Golis, Advanced Quality Concepts Ward Rummel, D&W Enterprises, LTD. 1 1.0

No Further Remedial Action Planned Decision Document for Site 3.

DTIC Science & Technology

1998-04-01

INSTALLATION RESTORATION PROGRAM No FURTHER REMEDIAL ACTION PLANNED DECISION DOCUMENT FOR SITE 3 FINAL MICHIGAN AIR NATIONAL GUARD ALPENA ...COMBAT READINESS TRAINING CENTER ALPENA , MICHIGAN April 1998 Air National Guard Andrews AFB, Maryland &nc QUALITY IMSmm«^ 19980519 204 XA REPORT...Document for Site 3 at Alpena CRTC, Alpena , MI. 6. AUTHOR(S) N/A 5. FUNDING NUMBERS 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Montgomery

The National Shipbuilding Research Program. Shipyard MACT Implementation Plan and Compliance Tools

DTIC Science & Technology

1996-06-01

display a currently valid OMB control number. 1. REPORT DATE JUN 1996 2. REPORT TYPE N/A 3. DATES COVERED - 4. TITLE AND SUBTITLE The National...ACHIEVABLE CONTROL TECHNOLOGY SECTION TWO: MODEL SHIPYARD IMPLEMENTATION PLAN SECTION THREE: THINNING RATION CALCULATION SHEETS FOR OPTIONS 2 & 3 AND...INTERPRETATION OF THE SHIPYARD MAXIMUM ACHIEVABLE CONTROL TECHNOLOGY EPA’s Maximum Achievable Control Technology Rule for Shipyards: A Plain English

Dual-Modulation, Dual-Wavelength, Optical Polarimetry System for Glucose Monitoring

DTIC Science & Technology

2016-08-26

dual-wavelength, optical polarimetry system for glucose monitoring 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER N/A 6. AUTHOR(S) 5d...JBO.21.8.087001] 14. ABSTRACT A dual modulation optical polarimetry system utilizing both laser intensity and polarization modulation was designed...varying birefringence, which is one of the major limitations to the realization of polarimetry for glucose monitoring in the eye. The high-speed less

Plasmonic Aptamer-Gold Nanoparticle Sensors for Small Molecule Fingerprint Identification

DTIC Science & Technology

2014-08-01

AFRL-RH-WP-TR-2014-0107 PLASMONIC APTAMER -GOLD NANOPARTICLE SENSORS FOR SMALL MOLECULE FINGERPRINT IDENTIFICATION Jorge Chávez Grant Slusher...Plasmonic Aptamer -Gold Nanoparticle Sensors for Small Molecule Fingerprint Identification 5a. CONTRACT NUMBER N/A 5b. GRANT NUMBER 5c. PROGRAM...The utilization of the plasmonic response of aptamer -gold nanoparticle conjugates (Apt-AuNPs) to design cross- reactive arrays for fingerprint

National Forest Health Monitoring Program Wisconsin Street Tree Assessment 2002-2003, NA-FR-02-08 Brief

Treesearch

Anne Buckelew Cumming; Daniel Twardus; Robert Hoehn; David Nowak; Manfred Mielke; Richard Rideout; Helen Butalla; Patricia Lebow

2008-01-01

Street trees grow along roadways within the public right-ofway. They are an important part of the urban forest due to their visibility to motorists and pedestrians, even if their numbers represent a small fraction of trees in urban areas. Little data are available that describe this resource at a large, statewide scale. Street trees, a subpopulation of the urban forest...

Deformation Driven Alloying and Transformation

DTIC Science & Technology

2015-03-03

OMB control number. PLEASE DO NOT RETURN YOUR FORM TO THE ABOVE ADDRESS. University of Wisconsin - Madison RESERACH & SPONSORED PROGRAMS 21 N. PARK...STREET SUITE 6401 MADISON, WI 53715 -1218 4-Dec-2014 ABSTRACT Number of Papers published in peer-reviewed journals: Number of Papers published in non peer...diffusion. Further study of the underlying mechanisms is warranted. (a) Papers published in peer-reviewed journals (N/A for none) Enter List of papers

Design for a Manufacturing Method for Memristor-Based Neuromorphic Computing Processors

DTIC Science & Technology

2013-03-01

DESIGN FOR A MANUFACTURING METHOD FOR MEMRISTOR- BASED NEUROMORPHIC COMPUTING PROCESSORS UNIVERSITY OF PITTSBURGH MARCH 2013...BASED NEUROMORPHIC COMPUTING PROCESSORS 5a. CONTRACT NUMBER FA8750-11-1-0271 5b. GRANT NUMBER N/A 5c. PROGRAM ELEMENT NUMBER 62788F 6. AUTHOR(S...synapses and implemented a neuromorphic computing system based on our proposed synapse designs. The robustness of our system is also evaluated by

Memristor-Based Synapse Design and Training Scheme for Neuromorphic Computing Architecture

DTIC Science & Technology

2012-06-01

system level built upon the conventional Von Neumann computer architecture [2][3]. Developing the neuromorphic architecture at chip level by...SCHEME FOR NEUROMORPHIC COMPUTING ARCHITECTURE 5a. CONTRACT NUMBER FA8750-11-2-0046 5b. GRANT NUMBER N/A 5c. PROGRAM ELEMENT NUMBER 62788F 6...creation of memristor-based neuromorphic computing architecture. Rather than the existing crossbar-based neuron network designs, we focus on memristor

Prototype for Meta-Algorithmic, Content-Aware Image Analysis

DTIC Science & Technology

2015-03-01

PROTOTYPE FOR META-ALGORITHMIC, CONTENT-AWARE IMAGE ANALYSIS UNIVERSITY OF VIRGINIA MARCH 2015 FINAL TECHNICAL REPORT...ALGORITHMIC, CONTENT-AWARE IMAGE ANALYSIS 5a. CONTRACT NUMBER FA8750-12-C-0181 5b. GRANT NUMBER N/A 5c. PROGRAM ELEMENT NUMBER 62305E 6. AUTHOR(S) S...approaches were studied in detail and their results on a sample dataset are presented. 15. SUBJECT TERMS Image Analysis , Computer Vision, Content

Recommendations to Commander, Naval Surface Forces, for Achieving a Strategic Approach to the Acquisition of Information Systems and Services

DTIC Science & Technology

2010-09-01

policy or position of the Department of Defense or the U.S. government . IRB Protocol number _______N/A______. 12a. DISTRIBUTION / AVAILABILITY...72 3. GAO Case Study of Commercial Transformation in Decision Making on IS Acquisition Spending (Case Study Located in Appendix C...Program FRE Fleet Readiness Enterprise GAO government Accountability Office IOC Initial Operating Capability xvi IS Information

Electronics: Mott Transistor: Fundamental Studies and Device Operation Mechanisms

DTIC Science & Technology

2016-03-21

display a currently valid OMB control number. PLEASE DO NOT RETURN YOUR FORM TO THE ABOVE ADDRESS. Harvard University Office for Sponsored Programs...including journal references , in the following categories: (b) Papers published in non-peer-reviewed journals (N/A for none) 03/21/2016 03/21/2016 03...limited kinetics of electron doping in correlated oxides, Applied Physics Letters (07 2015) TOTAL: 1 Books Number of Manuscripts: Patents Submitted

Evaluation of Effect of CMA Radius on SOQPSK Equalization

DTIC Science & Technology

2014-06-23

N/A 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Henry Umuolo, Habtamu Betelle and Solomon Thang, Dr. Arlene Cole-Rhodes and Dr. Farzad Moazzami 5d...MD 21251-0002 arlene.colerhodes@morgan.edu Attn: Farzad Moazzami 4 0 0 Cc: Henry Umuolo, Habtamu Betelle , Solomon Thang...EVALUATION OF EFFECT OF CMA RADIUS ON SOQPSK EQUALIZATION Henry Umuolo, Habtamu Betelle and Solomon Thang Faculty Advisors: Dr. Arlene Cole-Rhodes

Beyond Precision: Issues of Morality and Decision Making in Minimizing Collateral Casualties

DTIC Science & Technology

2003-04-28

possible contributions from moral judgment and decision making . As Fuller himself said, laws “can create the conditions essential for a rational ...BEYOND PRECISION: Issues of Morality and Decision Making in Minimizing Collateral Casualties Program in Arms Control, Disarmament, and...28 APR 2003 2. REPORT TYPE N/A 3. DATES COVERED - 4. TITLE AND SUBTITLE Beyond Precision: Issues of Morality and Decision Making in

ELECTIONS: Issues Affecting Military and Overseas Absentee Voters

DTIC Science & Technology

2001-05-09

Office GAO For Release on Delivery Expected at 2:30 p.m., EDT Wednesday, May 9, 2001 ELECTIONS Issues Affecting Military and Overseas Absentee Voters...Type N/A Dates Covered (from... to) ("DD MON YYYY") Title and Subtitle ELECTIONS: Issues Affecting Military and Overseas Absentee Voters Contract or...Grant Number Program Element Number Authors David M. Walker Project Number Task Number Work Unit Number Performing Organization Name(s) and

National Forest Health Monitoring Program Wisconsin Street Tree Assessment 2002-2003, NA-FR-02-08

Treesearch

Anne Cumming; Daniel Twardus; Robert Hoehn; David Nowak; Manfred Mielke; Richard Rideout; Helen Butalla; Patricia Lebow

2008-01-01

Street trees grow along roadways within the public right-of-way. They are an important part of the urban forest due to their visibility to motorists and pedestrians, even if their numbers represent a small fraction of trees in urban areas. Little data are available that describe this resource at a large, statewide scale. In 2000, the Forest Service, U.S....

FM Quieting Curves and Related Topics

DTIC Science & Technology

1977-08-01

Electronics Engineering Group (EEO) is organized as an independent group reorting, directly to -the Comwiander, Air ’Force Conmmunica-r tions Service (WOC...NUMBER N/A 7. AklTHO -() 6. CONTRACT OR GRANT NUMBER(#) /, .C...or.e M./ Kizer/ , ,/A 9. PERFORMING ORGANIZATION NAME AND ADDRESS 10. PROGRAM ELEMENT...in vestigial sideband modulation) and are separated from the carrier frequency by a frequency difference equal to the frequency of the baseband

Implementing Evidenced Based Oral Care for Critically Ill Patients

DTIC Science & Technology

2016-02-28

Tacoma, WA 98402 N/A 9. SPONSORING / MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10. SPONSOR/MONITOR’S ACRONYM(S) TriService Nursing Research...determined if an evidence-based oral care program resulted in increased nurses ’ knowledge and improved oral care practices compliance. Design: The project...critical care nursing education was conducted over a two-week period using the conceptual underpinning of the Iowa Model, the Diffusion of Innovation

Internet-Based Cervical Cytology Screening Program

DTIC Science & Technology

2005-04-01

and Second Trials of Each Pathologist. * Reference diagnostic category: NEG, ASCUS , LSIL > HSIL Pathologist 1 Interpretation. Negative or LSIL 24 (22...Principal Investigator: David C. Wdlbbur, M.D. Description of Subject Population: Women above the age of l18 years having Pap tests performe PURPOSE We...Subject Population: Women above the age of 18 years having Pay tests performed IRB Protocol Number: 2003P-001658 Sponsor Protocol Number: n/a Consent Form

Development of Medical Technology for Contingency Response to Marrow Toxic Agents

DTIC Science & Technology

2014-07-25

Research in Transplantation : Create a platform that facilitates multicenter collaboration and data management. 15. SUBJECT TERMS Research in HLA ...Confirmatory Testing OTTR Organ Transplant Tracking Record CTA Clinical Trial Application P2P Peer-to-Peer PBMC Peripheral Blood Mononuclear Cells...NUMBER Project 1, 2, 3, 4 5f. WORK UNIT NUMBER N/A 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) National Marrow Donor Program 3001

Sulfur dioxide alleviates programmed cell death in barley aleurone by acting as an antioxidant

PubMed Central

Yang, Feng; Huang, Zhong-Qin; Tang, Jun; Hu, Kang-Di

2017-01-01

Sulfur dioxide (SO2), a gaseous signaling molecule in animal cells, has recently been found to play a physiological role in plants. Here we studied the role of SO2 in gibberellic acid (GA3)-induced programmed cell death (PCD) in barley (Hordeum vulgare L.) aleurone layers. The application of the SO2 donor (NaHSO3/Na2SO3, 1:3 M/M) effectively alleviated PCD in barley aleurone layers in a dose-dependent manner with an optimal concentration of 50 μM. Further investigations showed that SO2 reduced the accumulation of hydrogen peroxide (H2O2), superoxide anion (⋅O2−) and malondialdehyde (MDA) in aleurone layers. Moreover, the activities of antioxidant enzymes such as superoxide dismutase (SOD), catalase (CAT), ascorbate peroxidase (APX), glutathione reductase (GR) and guaiacol peroxidase (POD) were enhanced by SO2 donor treatment. Meanwhile, lipoxygenase (LOX) activity was attenuated by SO2 donor treatment. Furthermore, an induction of endogenous H2S and NO were also observed in SO2-treated aleurone layers, suggesting interactions of SO2 with other well-known signaling molecules. Taken together, we show that SO2 negatively regulated PCD by acting as an antioxidant to scavenge excessive reactive oxygen species (ROS) generated during PCD. PMID:29155872

Coupled Hydrodynamic Instability Growth on Oblique Interfaces with a Reflected Rarefaction

NASA Astrophysics Data System (ADS)

Rasmus, A. M.; Flippo, K. A.; di Stefano, C. A.; Doss, F. W.; Hager, J. D.; Merritt, E. C.; Cardenas, T.; Schmidt, D. W.; Kline, J. L.; Kuranz, C. C.

2017-10-01

Hydrodynamic instabilities play an important role in the evolution of inertial confinement fusion and astrophysical phenomena. Three of the Omega-EP long pulse beams (10 ns square pulse, 14 kJ total energy, 1.1 mm spot size) drive a supported shock across a heavy-to-light, oblique, interface. Single- and double-mode initial conditions seed coupled Richtmyer-Meshkov (RM), Rayleigh-Taylor (RT), and Kelvin-Helmholtz (KH) growth. At early times, growth is dominated by RM and KH, whereas at late times a rarefaction from laser turn-off reaches the interface, leading to decompression and RT growth. The addition of a thirty degree tilt does not alter mix width to within experimental error bars, even while significantly altering spike and bubble morphology. The results of single and double-mode experiments along with simulations using the multi-physics hydro-code RAGE will be presented. This work performed under the auspices of the U.S. Department of Energy by LANL under contract DE-AC52-06NA25396. This work is funded by the NNSA-DS and SC-OFES Joint Program in High-Energy-Density Laboratory Plasmas, Grant Number DE-NA0002956. This material is partially supported by DOE Office of Science Graduate Student Research (SCGSR) program.

Resolution of singularities for multi-loop integrals

NASA Astrophysics Data System (ADS)

Bogner, Christian; Weinzierl, Stefan

2008-04-01

We report on a program for the numerical evaluation of divergent multi-loop integrals. The program is based on iterated sector decomposition. We improve the original algorithm of Binoth and Heinrich such that the program is guaranteed to terminate. The program can be used to compute numerically the Laurent expansion of divergent multi-loop integrals regulated by dimensional regularisation. The symbolic and the numerical steps of the algorithm are combined into one program. Program summaryProgram title: sector_decomposition Catalogue identifier: AEAG_v1_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/AEAG_v1_0.html Program obtainable from: CPC Program Library, Queen's University, Belfast, N. Ireland Licensing provisions: Standard CPC licence, http://cpc.cs.qub.ac.uk/licence/licence.html No. of lines in distributed program, including test data, etc.: 47 506 No. of bytes in distributed program, including test data, etc.: 328 485 Distribution format: tar.gz Programming language: C++ Computer: all Operating system: Unix RAM: Depending on the complexity of the problem Classification: 4.4 External routines: GiNaC, available from http://www.ginac.de, GNU scientific library, available from http://www.gnu.org/software/gsl Nature of problem: Computation of divergent multi-loop integrals. Solution method: Sector decomposition. Restrictions: Only limited by the available memory and CPU time. Running time: Depending on the complexity of the problem.

A quality-assurance assessment for constituents reported by the national atmospheric deposition program and the national trends network

NASA Astrophysics Data System (ADS)

See, Randolph B.; Schroder, LeRoy J.; Willoughby, Timothy C.

A continuing quality-assurance program has been operated by the U.S. Geological Survey to evaluate any bias introduced by routine handling, shipping, and laboratory analyses of wet-deposition samples collected in the National Atmospheric Deposition Program (NADP) and National Trends Network (NTN). Blind-audit samples having a variety of constituent concentrations and values were selected. Only blind-audit samples with constituent concentrations and values less than the 95th-percentile concentration for natural wet-deposition samples were included in the analysis. Of the major ions, there was a significant increase of Ca 2+, Mg 2+, Na 2+, K +, SO 42- and Cl -1 in samples handled according to standard protocols and shipped in NADP/NTN sample-collection buckets. For 1979-1987, graphs of smoothed data showing the estimated contamination in blind-audit samples indicate a decrease in the median concentration and ranges of Ca 2+, Mg 2+ and SO 42- contamination of blind-audit samples shipped in sample-collection buckets. Part of the contamination detected in blind-audit samples can be attributed to contact with the sample-collection bucket and lid; however, additional sources also seem to contaminate the blind-audit sample. Apparent decreases in the magnitude and range of sample contamination may be caused by differences in sample-collection bucket- and lid-washing procedures by the NADP/NTN Central Analytical Laboratory. Although the degree of bias is minimal for most constituents, summaries of the NADP/NTN data base may contain overestimates of Ca 2+, Mg 2+, Na -, K + and SO 42- and Cl - concentrations, and underestimates of H + concentrations.

AMDTreat 5.0+ with PHREEQC titration module to compute caustic chemical quantity, effluent quality, and sludge volume

USGS Publications Warehouse

Cravotta, Charles A.; Means, Brent P; Arthur, Willam; McKenzie, Robert M; Parkhurst, David L.

2015-01-01

Alkaline chemicals are commonly added to discharges from coal mines to increase pH and decrease concentrations of acidity and dissolved aluminum, iron, manganese, and associated metals. The annual cost of chemical treatment depends on the type and quantities of chemicals added and sludge produced. The AMDTreat computer program, initially developed in 2003, is widely used to compute such costs on the basis of the user-specified flow rate and water quality data for the untreated AMD. Although AMDTreat can use results of empirical titration of net-acidic or net-alkaline effluent with caustic chemicals to accurately estimate costs for treatment, such empirical data are rarely available. A titration simulation module using the geochemical program PHREEQC has been incorporated with AMDTreat 5.0+ to improve the capability of AMDTreat to estimate: (1) the quantity and cost of caustic chemicals to attain a target pH, (2) the chemical composition of the treated effluent, and (3) the volume of sludge produced by the treatment. The simulated titration results for selected caustic chemicals (NaOH, CaO, Ca(OH)2, Na2CO3, or NH3) without aeration or with pre-aeration can be compared with or used in place of empirical titration data to estimate chemical quantities, treated effluent composition, sludge volume (precipitated metals plus unreacted chemical), and associated treatment costs. This paper describes the development, evaluation, and potential utilization of the PHREEQC titration module with the new AMDTreat 5.0+ computer program available at http://www.amd.osmre.gov/.

Pathway out of poverty: a values-based college-community partnership to improve long-term outcomes of underrepresented students.

PubMed

Boyd, Jamie Kamailani; Kuuleialoha Kamaka, Sharmayne A; Braun, Kathryn L

2012-01-01

Native Hawaiians, representing 25% of Hawai'i's population, suffer socioeconomic and health strains as evidenced by overrepresentation in low-wage jobs without health insurance and a higher prevalence of chronic disease compared with Hawai'i's other ethnic groups. Native Hawaiians are more likely to attend community colleges than 4-year colleges and have high dropout rates. To describe a culturally relevant, community-based action research approach to build a program to keep Hawaiians in college to advance career options and improve long-term health and socioeconomic outcomes. Culturally relevant approaches that depended on participation from a variety of community partners were used to evaluate needs and design interventions. The Pathway Out of Poverty Program uses Hawaiian values and traditions of healthy living to lead students through a nursing pathway from nurse aide (NA) to licensed practical nurse (LPN) to registered nurse (RN), with inherent increases in wage-earning potential. In the first 3.5 years, 150 students enrolled in NA training, and 135 students (90%) graduated and were certified. Of the 135, 77 (57%) transitioned to higher education and 79% transitioned to jobs that offered health insurance (20% were in both groups). Of the 77 entering higher education, 33 (43%) aimed for a degree in nursing. Students expressed growing interest in health promotion for themselves, family members, and others. Community partners were key to developing a successful community college-based Pathway Program to help marginalized and other underrepresented students move from low-wage to living-wage jobs and improve their long-term health outcomes.

Basic research and data analysis for the National Geodetic Satellite program and for the Earth Surveys program

NASA Technical Reports Server (NTRS)

1972-01-01

Current research is reported on precise and accurate descriptions of the earth's surface and gravitational field and on time variations of geophysical parameters. A new computer program was written in connection with the adjustment of the BC-4 worldwide geometric satellite triangulation net. The possibility that an increment to accuracy could be transferred from a super-control net to the basic geodetic (first-order triangulation) was investigated. Coordinates of the NA9 solution were computed and were transformed to the NAD datum, based on GEOS 1 observations. Normal equations from observational data of several different systems and constraint equations were added and a single solution was obtained for the combined systems. Transformation parameters with constraints were determined, and the impact of computers on surveying and mapping is discussed.

Carbon Nanotube Biosensors for Space Molecule Detection and Clinical Molecular Diagnostics

NASA Technical Reports Server (NTRS)

Han, Jie

2001-01-01

Both space molecule detection and clinical molecule diagnostics need to develop ultra sensitive biosensors for detection of less than attomole molecules such as amino acids for DNA. However all the electrode sensor systems including those fabricated from the existing carbon nanotubes, have a background level of nA (nanoAmp). This has limited DNA or other molecule detection to nA level or molecules whose concentration is, much higher than attomole level. A program has been created by NASA and NCI (National Cancer Institute) to exploit the possibility of carbon nanotube based biosensors to solve this problem for both's interest. In this talk, I will present our effort on the evaluation and novel design of carbon nanotubes as electrode biosensors with strategies to minimize background currents while maximizing signal intensity.The fabrication of nanotube electrode arrays, immobilization of molecular probes on nanotube electrodes and in vitro biosensor testing will also be discussed.

Solution-Processed Flexible Organic Ferroelectric Phototransistor.

PubMed

Zhao, Qiang; Wang, Hanlin; Jiang, Lang; Zhen, Yonggang; Dong, Huanli; Hu, Wenping

2017-12-20

In this article, we demonstrate ferroelectric insulator, P(VDF-TrFE), can be integrated with red light sensitive polymeric semiconductor, P(DPP-TzBT), toward ferroelectric organic phototransistors (OPTs). This ferroelectricity-modulated phototransistor possesses different nonvolatile and tunable dark current states due to P(VDF-TrFE)'s remnant polarization. As a result, the OPT is endowed with a tunable dark current level ranging from 1 nA to 100 nA. Once the OPT is programmed or electrically polarized, its photo-to-dark (signal-to-noise) ratio can be "flexible" during photodetection process, without gate bias application. This kind of organic ferroelectric phototransistor has great potential in detecting wide ranges of light signals with good linearity. Moreover, its tuning mechanism discussed in this work can be helpful to understand the operation mechanism of organic phototransistor (OPT). It can be promising for novel photodetection application in plastic electronic devices.

Immunologic considerations for generating memory CD8 T cells through vaccination.

PubMed

Butler, Noah S; Nolz, Jeffrey C; Harty, John T

2011-07-01

Following infection or vaccination, naïve CD8 T cells that receive the appropriate integration of antigenic, co-stimulatory and inflammatory signals undergo a programmed series of biological changes that ultimately results in the generation of memory cells. Memory CD8 T cells, in contrast to naïve cells, more effectively limit or prevent pathogen re-infection because of both qualitative and quantitative changes that occur following their induction. Unlike vaccination strategies aimed at generating antibody production, the ability to generate protective memory CD8 T cells has proven more complicated and problematic. However, recent experimental results have revealed important principles regarding the molecular and genetic basis for memory CD8 T cell formation, as well as identified ways to manipulate their development through vaccination, resulting in potential new avenues to enhance protective immunity. © 2011 Blackwell Publishing Ltd.

Effect of radiation-induced xerostomia on the human oral microflora. Report no. 12 (final), 1 Jul 1971-30 Jun 1976

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dreizen, S.; Brown, L.R.

1976-06-30

The caries-conducive impact of xerostomia was studied in 42 irradiated cancer patients. The radiation-induced xerostomia was paralleled by changes in the physical, microbial, biochemical, immunologic and dietary parameters of cariogenicity that collectively comprised an overwhelming caries challenge. Microbiologically, significant xerostomia-related increases in Strep. mutans, lactobacilli, staphylococci, yeasts and catalase-positive diphtheroids were accompanied by decreases in Strep. sanguis, bacteroides and fusobacteria in each of the 5 microenvironments tested. The scanty xerostomic saliva contained greater amounts of Na(+), Cl(-), Ca(++), Mg(++), Prot(-), lysozyme, IgA and IgG and considerably less HCO3(-). The increased concentrations of caries protective electrolytes and immunoproteins were negated bymore » huge reductions in total daily saliva output. The xerostomia created caries challenge was almost completely neutralized by a preventive program of daily topical NaF applications and strict oral hygiene. (GRA)« less

Plasma Torch Development Activities at Archimedes

NASA Astrophysics Data System (ADS)

Davis Lee, W.; Agnew, Steve; Chamberlin, Fred; Hilsabeck, Terry; Meekins, Mike; Plaisted, Ryan; Putvinski, Sergei; Umstadter, Karl; Yung, Shui

2004-11-01

The Archimedes Demonstration Unit (ADU) is a large scale implementation (L ≃ 4.0 m, a ≃ 0.37 m) of the plasma mass filter. The filter concept uses perpendicular \\overrightarrowE and \\overrightarrowB fields to separate material by atomic mass at high throughputs, with applications to nuclear waste remediation. Fueling the filter plasma with molten waste is one of the fundamental challenges of the ADU program, and this has been achieved using an inductively coupled plasma torch. Experiments have been performed with molten NaOH, a primary constituent of the waste to be treated. The melt is pumped to the bottom of the torch and nebulized using a 20 kHz sonic source. The nebulized NaOH mist is then evaporated by the torch and injected into the central region of the ADU. Vapor jet characteristics and ionization rates have been measured. The experimental setup and data will be presented.

Experimental Potential Energy Curve for the 43 Π Electronic State of NaCs

NASA Astrophysics Data System (ADS)

Steely, Andrew; Cooper, Hannah; Zain, Hareem; Whipp, Ciara; Faust, Carl; Kortyna, Andrew; Huennekens, John

2017-04-01

We present results from experimental studies of the 43 Π electronic state of the NaCs molecule. This electronic state is interesting in that its potential energy curve likely exhibits a double minimum. As a result, interference effects are observed in the resolved bound-free fluorescence spectra. The optical-optical double resonance method was used to obtain Doppler-free excitation spectra for the 43 Π state. This dataset of measured level energies was expanded largely by observing fluorescence from levels populated by collisions. To aid in level assignments, simulations of resolved bound-free fluorescence spectra were calculated using the BCONT program (R. J. Le Roy, University of Waterloo). Spectroscopic constants were determined to summarize data belonging to inner well, outer well, and above barrier regions of the electronic state. Current work focuses on using the IPA method to construct an experimental potential energy curve. Work supported by NSF and Susquehanna University.

Gamma signatures of the C-BORD Tagged Neutron Inspection System

NASA Astrophysics Data System (ADS)

Sardet, A.; Pérot, B.; Carasco, C.; Sannié, G.; Moretto, S.; Nebbia, G.; Fontana, C.; Pino, F.; Iovene, A.; Tintori, C.

2018-01-01

In the frame of C-BORD project (H2020 program of the EU), a Rapidly relocatable Tagged Neutron Inspection System (RRTNIS) is being developed to non-intrusively detect explosives, chemical threats, and other illicit goods in cargo containers. Material identification is performed through gamma spectroscopy, using twenty NaI detectors and four LaBr3 detectors, to determine the different elements composing the inspected item from their specific gamma signatures induced by fast neutrons. This is performed using an unfolding algorithm to decompose the energy spectrum of a suspect item, selected by X-ray radiography and on which the RRTNIS inspection is focused, on a database of pure element gamma signatures. This paper reports on simulated signatures for the NaI and LaBr3 detectors, constructed using the MCNP6 code. First experimental spectra of a few elements of interest are also presented.

Collapsing Radiative Shocks in Xenon Gas on the Omega Laser

NASA Astrophysics Data System (ADS)

Reighard, A. B.; Glendinning, S. G.; Knauer, J.; Bouquet, S.; Koenig, M.

2005-10-01

A number of astrophysical systems involve radiative shocks that collapse spatially in response to energy lost through radiation, producing thin shells believed to be Vishniac unstable. We report experiments intended to study such collapsing shocks. The Omega laser drives a thin slab of material at >100 km/s through Xe gas. Simulations predict a collapsed layer in which the density reaches 45 times initial density. X-ray backlighting techniques have yielded images of a collapsed shock compressed to <1/25 its initial thickness (45 μm) at a speed of ˜100 km/s when the shock has traveled 1.3 mm. Optical depth before and behind the shock is important for comparison to astrophysical systems. This research was sponsored by the National Nuclear Security Administration under the Stewardship Science Academic Alliances program through DOE Research Grants DE-FG52-03NA00064, DE-FG53-2005-NA26014, and other grants and contracts.

Astrophysical Connections to Collapsing Radiative Shock Experiments

NASA Astrophysics Data System (ADS)

Reighard, A. B.; Hansen, J. F.; Bouquet, S.; Koenig, M.

2005-10-01

Radiative shocks occur in many high-energy density explosions, but prove difficult to create in laboratory experiments or to fully model with astrophysical codes. Low astrophysical densities combined with powerful explosions provide ideal conditions for producing radiative shocks. Here we describe an experiment significant to astrophysical shocks, which produces a driven, planar radiative shock in low density Xe gas. Including radiation effects precludes scaling experiments directly to astrophysical conditions via Euler equations, as can be done in purely hydrodynamic experiments. We use optical depth considerations to make comparisons between the driven shock in xenon and specific astrophysical phenomena. This planar shock may be subject to thin shell instabilities similar to those affecting the evolution of astrophysical shocks. This research was sponsored by the National Nuclear Security Administration under the Stewardship Science Academic Alliances program through DOE Research Grants DE-FG52-03NA00064, DE-FG53-2005-NA26014, and other grants and contracts.

Design of a 25-kWe Surface Reactor System Based on SNAP Reactor Technologies

NASA Astrophysics Data System (ADS)

Dixon, David D.; Hiatt, Matthew T.; Poston, David I.; Kapernick, Richard J.

2006-01-01

A Hastelloy-X clad, sodium-potassium (NaK-78) cooled, moderated spectrum reactor using uranium zirconium hydride (UZrH) fuel based on the SNAP program reactors is a promising design for use in surface power systems. This paper presents a 98 kWth reactor for a power system the uses multiple Stirling engines to produce 25 kWe-net for 5 years. The design utilizes a pin type geometry containing UZrHx fuel clad with Hastelloy-X and NaK-78 flowing around the pins as coolant. A compelling feature of this design is its use of 49.9% enriched U, allowing it to be classified as a category III-D attractiveness and reducing facility costs relative to highly-enriched space reactor concepts. Presented below are both the design and an analysis of this reactor's criticality under various safety and operations scenarios.

Development of a phase-change thermal storage system using modified anhydrous sodium hydroxide for solar electric power generation

NASA Technical Reports Server (NTRS)

Cohen, B. M.; Rice, R. E.; Rowny, P. E.

1978-01-01

A thermal storage system for use in solar power electricity generation was investigated analytically and experimentally. The thermal storage medium is principally anhydrous NaOH with 8% NaNO3 and 0.2% MnO2. Heat is charged into storage at 584 K and discharged from storage at 582 K by Therminol-66. Physical and thermophysical properties of the storage medium were measured. A mathematical simulation and computer program describing the operation of the system were developed. A 1/10 scale model of a system capable of storing and delivering 3.1 x 10 to the 6th power kJ of heat was designed, built, and tested. Tests included steady state charging, discharging, idling, and charge-discharge conditions simulating a solar daily cycle. Experimental data and computer-predicted results are correlated. A reference design including cost estimates of the full-size system was developed.

APPR-1 RESEARCH AND DEVELOPMENT PROGRAM DECONTAMINATION PROGRAM. TASK II. VOLUME II. EVALUATION OF CHEMICAL AGENTS FOR NUCLEAR REACTOR DECONTAMINATION

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zegger, J.L.; Pancer, G.P.

1959-02-15

The caustic permanganante-rinse decontamination studies were performed to determine optimum operating conditions as well as the metallurgical effects of the treatment. A treatment with 10% NaOH and 5% potassium by a rinse with a 5% ammorium citrate, 2% citric acid and 1/2% Versene solution was chosen for the decontamination of a stainless steel steam generator, Decontamination factors of greater than 50 were obtained in loop tests using the above treatment. Corrosion and metallurgical results indicated a total penetration of less than 0.01 mil on annealed type 304 stainless steel with no evidence of any deleterious effects. (auth)

IL-10 Producing B Cells Ability to Induce Regulatory T Cells Is Maintained in Rheumatoid Arthritis

PubMed Central

Mielle, Julie; Audo, Rachel; Hahne, Michael; Macia, Laurence; Combe, Bernard; Morel, Jacques; Daien, Claire

2018-01-01

Despite growing evidence highlighting the relevance of increasing IL-10-producing B cells (B10+cells) in autoimmune diseases, their functions in patients are still unknown. The aim of this study was to evaluate the functions of CpG-induced B10+ cells isolated from healthy controls (HC) and rheumatoid arthritis (RA) patients, on naïve T cell differentiation. We demonstrated that CpG-induced B10+ cells from HC drove naïve T cell differentiation toward regulatory T cells (Treg cells) and IL-10-producing T cells (Tr1) through IL-10 secretion and cellular contacts. B10+ cells from HC did not decrease T helper 1 (Th1) nor and tumor necrosis factor α producing T cell (TNFα+ T cell) differentiation. We showed that in RA, B10+ cells could also induce Treg cells and Tr1 from naïve T cells. Contrary to HC, B10+ cells from RA patients increased naïve T cell conversion into Th1. Interestingly, PD-L2, a programmed death-1 (PD-1) ligand that inhibits PD-L1 and promotes Th1 differentiation, was overexpressed on RA B10+ cells compared to HC B10+ cells. Together, our findings showed that CpG-induced B10+ cells may be used to increase Treg cells in patients with RA. However, CpG may not be the most adequate stimuli as CpG-induced B10+ cells also increased inflammatory T cells in those patients. PMID:29774031

Young science journalism: writing popular scientific articles may contribute to an increase of high-school students' interest in the natural sciences

NASA Astrophysics Data System (ADS)

Simon, Uwe K.; Steindl, Hanna; Larcher, Nicole; Kulac, Helga; Hotter, Annelies

2016-03-01

Far too few high-school students choose subjects from the natural sciences (NaSc) for their majors in many countries. Even fewer study biology, chemistry or physics at university. Those, that do, often lack training to present and discuss scientific results and ideas in texts. To meet these challenges the center for didactics of biology of Graz University has set up the program Young Science Journalism. This new workshop-based interdisciplinary concept was tested in an exploratory study with grade 10 students of one Austrian high school, engaging both the biology and the German teacher of the class. It was our aim to raise students' interest in the NaSc by encouraging them to write popular scientific articles about self-chosen topics, and to help them improve their writing competence. In this paper we focus on interest development through writing. Results from this pilot study were promising. Using a mixed-method approach (comparing pre- and post-test questionnaires and semi-structured interviews from different time points analyzed qualitatively), we found that almost all students valued the project-related work highly. Most of them showed higher interest in the NaSc at project end with girls, in average, seeming to profit more from project participation. We thus recommend integrating such writing tasks into school curricula to increase students' interest in NaSc or to even create new interest. Additionally, we introduce a network presentation of questionnaire data as a powerful tool to visualize the effect of an intervention on individual students and student profile groups.

Detection Of Malware Collusion With Static Dependence Analysis On Inter-App Communication

DTIC Science & Technology

2016-12-08

DETECTION OF MALWARE COLLUSION WITH STATIC DEPENDENCE ANALYSIS ON INTER-APP COMMUNICATION VIRGINIA TECH DECEMBER 2016 FINAL TECHNICAL REPORT... DEPENDENCE ANALYSIS ON INTER-APP COMMUNICATION 5a. CONTRACT NUMBER FA8750-15-2-0076 5b. GRANT NUMBER N/A 5c. PROGRAM ELEMENT NUMBER 61101E 6. AUTHOR(S...exploited. 15. SUBJECT TERMS Malware Collusion; Inter-App Communication; Static Dependence Analysis 16. SECURITY CLASSIFICATION OF: 17. LIMITATION OF

DESIGN METHODOLOGIES AND TOOLS FOR SINGLE-FLUX QUANTUM LOGIC CIRCUITS

DTIC Science & Technology

2017-10-01

DESIGN METHODOLOGIES AND TOOLS FOR SINGLE-FLUX QUANTUM LOGIC CIRCUITS UNIVERSITY OF SOUTHERN CALIFORNIA OCTOBER 2017 FINAL...SUBTITLE DESIGN METHODOLOGIES AND TOOLS FOR SINGLE-FLUX QUANTUM LOGIC CIRCUITS 5a. CONTRACT NUMBER FA8750-15-C-0203 5b. GRANT NUMBER N/A 5c. PROGRAM...of this project was to investigate the state-of-the-art in design and optimization of single-flux quantum (SFQ) logic circuits, e.g., RSFQ and ERSFQ

Design for Production Manual. Volume 2. Design/Production Integration

DTIC Science & Technology

1985-12-01

woodworking equipment such as circular saw, cross cut saw, planer / thicknesser and sander. There is considerable use of hand tools in the shop. Joinery inclucies...PROGRAM BY SOCIETY OF NAVAL ARCHITECTS AND MARINE ENGINEERS SHIP PRODUCTION COMMITTEE PANEL SP- 4 DESIGN PRODUCTION INTEGRATION CONTRACT DTMA91-82-C...DEC 1985 2. REPORT TYPE N/A 3. DATES COVERED - 4 . TITLE AND SUBTITLE Design for Production Manual Volume 2 of 3 Design/Production

Air Force Space Systems Development Program

DTIC Science & Technology

1959-10-20

the inumnission of revels/flee of which le ony areneer N as sererliorial4 porno is prehibiled by law. 2. Bombardment Satellite The feasibility and...which in soy wanner Man voossfitswizod porno is osohibitod by low. distress signals ’and re-transmission with location data to a ground station can be...Seahme 713 and 794. Na transmission or wavolotion of which in any 111111111111M ho an onoolitorizatt porno is prohibited by low. Appendix B

Analysis and Prediction of Sea Ice Evolution using Koopman Mode Decomposition Techniques

DTIC Science & Technology

2018-04-30

Title: Analysis and Prediction of Sea Ice Evolution using Koopman Mode Decomposition Techniques Subject: Monthly Progress Report Period of...Resources: N/A TOTAL: $18,687 2 TECHNICAL STATUS REPORT Abstract The program goal is analysis of sea ice dynamical behavior using Koopman Mode Decompo...sition (KMD) techniques. The work in the program’s first month consisted of improvements to data processing code, inclusion of additional arctic sea ice

Hybrid Circuit Quantum Electrodynamics: Coupling a Single Silicon Spin Qubit to a Photon

DTIC Science & Technology

2015-01-01

HYBRID CIRCUIT QUANTUM ELECTRODYNAMICS: COUPLING A SINGLE SILICON SPIN QUBIT TO A PHOTON PRINCETON UNIVERSITY JANUARY 2015 FINAL...SILICON SPIN QUBIT TO A PHOTON 5a. CONTRACT NUMBER FA8750-12-2-0296 5b. GRANT NUMBER N/A 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Jason R. Petta...architectures. 15. SUBJECT TERMS Quantum Computing, Quantum Hybrid Circuits, Quantum Electrodynamics, Coupling a Single Silicon Spin Qubit to a Photon

Efficacy of Two Novel Anodic Coatings for Enhanced Corrosion Protection of Aluminum Armor Alloys

DTIC Science & Technology

2014-01-01

nitrate solution of a given metal electrolytically impregnating the porous oxide with the desired metal (5)—for example, silicon (Si) and silver (Ag...performed using the same equipment and data acquisition program previously described. Cells were filled with a 3.5% sodium chloride solution and the...electrochemical impedance spectroscopy h hour HATE Hydraulic Adhesion Test Equipment in inch NaCl sodium chloride OCP open circuit potential OSD

Biomarkers for Early Detection of Clinically Relevant Prostate Cancer: A Multi-Institutional Validation Trial

DTIC Science & Technology

2015-10-01

Suzanne Kolb 12 Project Role: Project Coordinator Researcher Identifier (e.g. ORCID ID): N/A Nearest person month worked: 5 person months...Contribution to Project: Ms. Kolb works under the direction of Drs. Lin and Newcomb to fulfill daily fiscal and administrative functions of the...program. She monitors subaward budgets, provides logistical support. Ms. Kolb works closely with the PASS Deputy Director to maintain IRB files

Biomarkers for Early Detection of Clinically Relevant Prostate Cancer: A Multi-Institutional Validation Trial

DTIC Science & Technology

2015-10-01

Name: Suzanne Kolb 12 Project Role: Project Coordinator Researcher Identifier (e.g. ORCID ID): N/A Nearest person month worked: 5 person...months Contribution to Project: Ms. Kolb works under the direction of Drs. Lin and Newcomb to fulfill daily fiscal and administrative functions of the...program. She monitors subaward budgets, provides logistical support. Ms. Kolb works closely with the PASS Deputy Director to maintain IRB files

Employee Involvement - White-Collar Work Force

DTIC Science & Technology

1993-01-01

a currently valid OMB control number. 1. REPORT DATE JAN 1993 2. REPORT TYPE N/A 3. DATES COVERED - 4. TITLE AND SUBTITLE Employee ...Involvement - White-Collar Work Force 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e. TASK NUMBER...34Persons acting on behalf of the Maritime Administration" includes any employee , contractor, or subcontractor to the contractor of the Maritime

A Coaching Intervention to Promote Nutrition and Bone Health in Deployed Soldiers

DTIC Science & Technology

2015-03-13

to Promote Nutrition and Bone Health in Deployed Soldiers 5b. GRANT NUMBER HU0001-10-1-TS15 5c. PROGRAM ELEMENT NUMBER N/A 6. AUTHOR(S...Purpose: The purpose of this study was to determine if telehealth coaching is superior to one-time nutrition and fitness education regarding...leisure activities. All soldiers received one-time nutrition and fitness education prior to deployment; Telehealth Group received health-related

Cleaning residual NaK in the fast flux test facility fuel storage cooling system

DOE Office of Scientific and Technical Information (OSTI.GOV)

Burke, T.M.; Church, W.R.; Hodgson, K.M.

2008-01-15

The Fast Flux Test Facility (FFTF), located on the U.S. Department of Energy's Hanford Reservation, is a liquid metal-cooled test reactor. The FFTF was constructed to support the U.S. Liquid Metal Fast Breeder Reactor Program. The bulk of the alkali metal (sodium and NaK) has been drained and will be stored onsite prior to final disposition. Residual NaK needed to be removed from the pipes, pumps, heat exchangers, tanks, and vessels in the Fuel Storage Facility (FSF) cooling system. The cooling system was drained in 2004 leaving residual NaK in the pipes and equipment. The estimated residual NaK volume wasmore » 76 liters in the storage tank, 1.9 liters in the expansion tank, and 19-39 liters in the heat transfer loop. The residual NaK volume in the remainder of the system was expected to be very small, consisting of films, droplets, and very small pools. The NaK in the FSF Cooling System was not radiologically contaminated. The portions of the cooling system to be cleaned were divided into four groups: 1. The storage tank, filter, pump, and associated piping; 2. The heat exchanger, expansion tank, and associated piping; 3. Argon supply piping; 4. In-vessel heat transfer loop. The cleaning was contracted to Creative Engineers, Inc. (CEI) and they used their superheated steam process to clean the cooling system. It has been concluded that during the modification activities (prior to CEI coming onsite) to prepare the NaK Cooling System for cleaning, tank T-914 was pressurized relative to the In-Vessel NaK Cooler and NaK was pushed from the tank back into the Cooler and that on November 6, 2005, when the gas purge through the In-Vessel NaK Cooler was increased from 141.6 slm to 283.2 slm, NaK was forced from the In-Vessel NaK Cooler and it contacted water in the vent line and/or scrubber. The gases from the reaction then traveled back through the vent line coating the internal surface of the vent line with NaK and NaK reaction products. The hot gases also exited the scrubber through the stack and due to the temperature of the gas, the hydrogen auto ignited when it mixed with the oxygen in the air. There was no damage to equipment, no injuries, and no significant release of hazardous material. Even though the FSF Cooling System is the only system at FFTF that contains residual NaK, there are lessons to be learned from this event that can be applied to future residual sodium removal activities. The lessons learned are: - Before cleaning equipment containing residual alkali metal the volume of alkali metal in the equipment should be minimized to the extent practical. As much as possible, reconfirm the amount and location of the alkali metal immediately prior to cleaning, especially if additional evolutions have been performed or significant time has passed. This is especially true for small diameter pipe (<20.3 centimeters diameter) that is being cleaned in place since gas flow is more likely to move the alkali metal. Potential confirmation methods could include visual inspection (difficult in all-metal systems), nondestructive examination (e.g., ultrasonic measurements) and repeating previous evolutions used to drain the system. Also, expect to find alkali metal in places it would not reasonably be expected to be. - Staff with an intimate knowledge of the plant equipment and the bulk alkali metal draining activities is critical to being able to confirm the amount and locations of the alkali metal residuals and to safely clean the residuals. - Minimize the potential for movement of alkali metal during cleaning or limit the distance and locations into which alkali metal can move. - Recognize that when working with alkali metal reactions, occasional pops and bangs are to be anticipated. - Pre-plan emergency responses to unplanned events to assure responses planned for an operating reactor are appropriate for the deactivation phase.« less

Acceptability of an e-learning program to help nursing assistants manage relationship conflict in nursing homes.

PubMed

Marziali, Elsa; Mackenzie, Corey Scott; Tchernikov, Illia

2015-02-01

Management of nursing assistants' (NAs) emotional stress from relationship conflicts with residents, families, and coworkers is rarely the focus of educational programs. Our objective was to gather feedback from NAs and their nursing supervisors (NSs) about the utility of our e-learning program for managing relationship stress. A total of 147 NAs and their NSs from 17 long-term care homes viewed the educational modules (DVD slides with voice-over), either individually or in small groups, and provided feedback using conference call focus groups. Qualitative analysis of NA feedback showed that workplace relationship conflict stress was associated with workload and the absence of a forum for discussing relationship conflicts that was not acknowledged by NSs. This accessible e-learning program provides NAs with strategies for managing stressful emotions arising from workplace relationship conflict situations and underscores the importance of supervisory support and team collaboration in coping with emotionally evoked workplace stress. © The Author(s) 2014.

The Recovery Process When Participating in Cancer Support and Rehabilitation Programs in Sweden

PubMed Central

Melin-Johansson, Christina; Öhlén, Joakim; Koinberg, Ingalill; Berg, Linda; Nolbris, Margaretha Jenholt

2015-01-01

The aim was to illuminate the meaning of participating in support and rehabilitation programs described by people diagnosed with cancer. Nineteen persons were interviewed in focus groups and face-to-face. Data were analyzed with a qualitative phenomenological hermeneutical method for researching lived experiences. Interpretation proceeded through three phases: naïve reading, structural analysis, and comprehensive understanding. Three themes were disclosed: receiving support for recovery when being most vulnerable, recapturing capabilities through supportive activities, and searching to find stability and well-being in a changed life situation. Participating in the programs was an existential transition from living in an unpredictable situation that was turned into something meaningful. Recovery did not mean the return to a state of normality; rather, it meant a continuing recovery from cancer treatments and symptoms involving recapturing capabilities and searching for a balance in a forever changed life. This study provides new insights about the experiences of participating in cancer support and rehabilitation programs. PMID:28462312

Assessment of laparoscopic skills of Gynecology and Obstetrics residents after a training program.

PubMed

Fernandes, Carla Ferreira Kikuchi; Ruano, José Maria Cordeiro; Kati, Lea Mina; Noguti, Alberto Sinhiti; Girão, Manoel João Batista Castello; Sartori, Marair Gracio Ferreira

2016-01-01

To evaluate laparoscopic skills of third-year Gynecology and Obstetrics residents after training at a training and surgical experimentation center. Use of a prospective questionnaire analyzing demographic data, medical residency, skills, competences, and training in a box trainer and in pigs. After the training, there was significant improvement in laparoscopic skills according to the residents (before 1.3/after 2.7; p=0.000) and preceptors (before 2.1/after 4.8; p=0.000). There was also significant improvement in the feeling of competence in surgeries with level 1 and 2 of difficulty. All residents approved the training. The training was distributed into 12 hours in the box trainer and 20 hours in animals, and led to better laparoscopic skills and a feeling of more surgical competence in laparoscopic surgery levels 1 and 2. Avaliar a habilidade laparoscópica dos residentes do terceiro ano de residência médica em Ginecologia e Obstetrícia após treinamento em um centro de treinamento e experimentação cirúrgica. Aplicação de questionário de forma prospectiva analisando dados demográficos, da residência médica, da habilidade, da competência e do treinamento em caixa preta e em porcas. Após o treinamento, houve melhora da habilidade em laparoscopia de forma significativa na avaliação dos residentes (antes 1,3/depois 2,7; p=0,000) e preceptores (antes 2,1/depois 4,8; p=0,000). Houve melhora significativa na sensação de competência em cirurgias de níveis 1 e 2 de dificuldade. Todos os residentes aprovaram o treinamento. O treinamento dividido em 12 horas de caixa preta e 20 horas em animais trouxe melhora na habilidade em laparoscopia e na sensação de melhora na competência cirúrgica em cirurgias laparoscópicas de níveis 1 e 2.

The effect of sea-water intrusion due to the large scale construction in a coastal region

NASA Astrophysics Data System (ADS)

Hyun, S.; Jin, S.; Woo, N. C.; Lee, J.; Lee, H.; Kim, Y.

2010-12-01

This study was carried out for estimating the seawater intrusion at the disturbed aquifer by a large scale construction when building a power plant in a coastal region, located in southeastern part of the Korean peninsula. Groundwater sampling and vertical profiling of electrical conductivity(EC) for 8 monitoring wells were carried. EC profiling results shows that maximum EC for PW-5, 6 and 7 is over 40 mS/cm, for PZ-1, 3, 4 and 8 is 18.76, 4.46, 26.16, 21.42 mS/cm and for PZ-2 is 0.79 mS/cm,respectively. Chemical composition of water samples shows that water types of Na-Cl for PZ-5, 6, and 7 (excavated and backfilled area), Na-Cl-SO4 for PZ-4 and PZ-8, Na-Ca-Mg-Cl for PZ-1, Ca-Na-SO4-Cl for PZ-2, and Mg-Ca-Na-SO4 for PZ-3. In addition, the bivariate plot of SO4/Cl(meq ratios) and SO4(mmol/L) indicates that PZ-4, 5, 6, 7 and 8 appear to be seawater, PZ-1 is located at mixing zone between freshwater and seawater, and PZ-2 is freshwater. However, based on the high SO42- level and (HCO3-/Sum anions} ratio less than 0.8, groundwater at PZ-3 seems to show the gypsum dissolution. The gypsum dissolution was attributed to the effect of sea-water intrusion on ageing of lean concrete that was used for backfill around the PZ-3. Key words : large scale construction, EC profiling, hydrochemistry, sea-water intrusion, concrete ageing Acknowledgement This study has been carried out under the Nuclear R&D Program [No. 2010-0001070] supported by the Ministry of Education, Science and Technology, Republic of Korea.

Understanding Group and Leader (UGL) trainers' personality characteristics and affective profiles

PubMed Central

Rapp Ricciardi, Max; Åkerman, Jeanette; Eerikäinen, Peter; Ambjörnsson, Annika; Andersson Arntén, Ann-Christine; Mihailovic, Marko; Archer, Trevor; Garcia, Danilo

2014-01-01

Background: The Understanding Group and Leader (UGL), provided by the Swedish National Defense College and mentored by UGL-trainers, is one of the most popular management programs among civilians in Sweden. However, there is a lack of scientific evidence regarding the training. We used the affective profile model (i.e., the combination of positive, PA, and negative affect, NA) to mapp important markers of empowerment, self-awareness, adaptive coping skills, and maturity among the UGL-trainers. The aims were: (1) to compare profiles between UGL-trainers and managers/supervisors and (2) to investigate differences in personal characteristics. Method: UGL-trainers (N = 153) and the comparison group (104 Swedish Chiefs of Police) completed an online survey on optimism, self-esteem, locus of control, and affect. The four profiles are: self-fulfilling (high PA, low NA), high affective (high PA, high NA), low affective (high PA, low NA), and self-destructive (low PA, high NA). Results: The self-fulfilling profile was more common among UGL-trainers (25.70%) than among Chiefs of Police (19.20%). UGL-trainers, compared to Chiefs of Police, were more likely to express a self-fulling than a low affective profile (OR = 2.22, p < 0.05) and a high affective than a low affective profile (OR = 1.43, p < 0.001). UGL-trainers with a self-fulfilling profile, compared to those with a self-destructive profile, scored higher in optimism, higher in self-esteem, and lower in external locus of control. Conclusions: The probability of self-fulfillment rather than low affectivity was higher among UGL-trainers. Self-fulfillment was associated to markers of self-awareness and adaptive coping skills. However, the most common profile was the low affective, which is associated to low performance during stress, low degree of personal development, low degree of purpose in life, and low resilience. Hence, it might be important for UGL-trainers to have a continuous training in awareness after certification. PMID:25374553

Perinatal α-tocopherol overload programs alterations in kidney development and renal angiotensin II signaling pathways at birth and at juvenile age: Mechanisms underlying the development of elevated blood pressure.

PubMed

Ribeiro, Valdilene S; Cabral, Edjair V; Vieira, Leucio D; Aires, Regina S; Farias, Juliane S; Muzi-Filho, Humberto; Vieyra, Adalberto; Paixão, Ana D

2018-07-01

α-Tocopherol (α-Toc) overload increases the risk of dying in humans (E.R. Miller III et al. Meta-analysis: high-dosage vitamin E supplementation may increase all-cause mortality Ann Int Med. 142 (2005) 37-46), and overload during early development leads to elevation of blood pressure at adult life, but the mechanism(s) remains unknown. We hypothesized that α-Toc overload during organogenesis affects the renal renin angiotensin system (RAS) components and renal Na + handling, culminating with late elevated blood pressure. Pregnant Wistar rats received α-Toc or the superoxide dismutase mimetic tempol throughout pregnancy. We evaluated components of the intrarenal renin angiotensin system in neonate and juvenile offspring: Ang II-positive cells, Ang II receptors (AT 1 and AT 2 ), linked protein kinases, O 2 - production, NADPH oxidase abundance, lipid peroxidation and activity of Na + -transporting ATPases. In juvenile offspring we followed the evolution of arterial blood pressure. Neonates from α-Toc and tempol mothers presented with accentuated retardment in tubular development, pronounced decrease in glomerular Ang II-positive cells and AT 1 /AT 2 ratio, intense production of O 2 - and upregulation of the α, ε and λ PKC isoforms. α-Toc decreased or augmented the abundance of renal (Na + +K + )ATPase depending on the age and α-Toc dose. In juvenile rats the number of Ang II-positive cells returned to control values as well as PKCα, but co-existing with marked upregulation in the activity of (Na + +K + ) and Na + -ATPase and elevated arterial pressure at 30 days. We conclude that the mechanisms of these alterations rely on selective targeting of renal RAS components through genic and pro-oxidant effects of the vitamin. Copyright © 2018 Elsevier B.V. All rights reserved.

Direct sampling graphite furnace atomic absorption spectrometry - feasibility of Na and K determination in desalted crude oil

NASA Astrophysics Data System (ADS)

Seeger, Tassia S.; Machado, Eduarda Q.; Flores, Erico M. M.; Mello, Paola A.; Duarte, Fabio A.

2018-03-01

In this study, Na and K were determined in desalted crude oil by direct sampling graphite furnace atomic absorption spectrometry (DS-GF AAS), with the use of a Zeeman-effect background correction system with variable magnetic field. The analysis was performed in low and high sensitivity conditions. Sodium determination was performed in two low-sensitivity conditions: 1) main absorption line (589.0 nm), gas stop flow during the atomization step and 3-field dynamic mode (0.6-0.8 T); and 2) secondary absorption line (330.3 nm), gas stop flow during the atomization and 2-field mode (0.8 T). In K determination, some parameters, such as high-sensitivity mode, main absorption line (766.5 nm), gas stop flow during the atomization and 2-field mode (0.8 T), were used. Suitability of chemical modifiers, such as Pd and W-Ir was also evaluated. The heating program for Na and K was based on the pyrolysis and atomization curves. Calibration was performed by aqueous standards. Accuracy was evaluated by the analysis of Green Petroleum Coke (SRM NIST 2718) and Trace Elements in Fuel Oil (SRM NIST 1634c). Recovery tests were also performed and results were compared with those obtained by GF AAS after crude oil digestion by microwave-assisted digestion. The characteristic mass of Na was 17.1 pg and 0.46 ng in conditions 1 and 2, respectively, while the one of K was 1.4 pg. Limits of detection and quantification by DS-GF AAS were 30 and 40 ng g-1 for Na and 3.2 and 4.2 ng g-1 for K, respectively. Sodium and K were determined in three crude oil samples with API density ranging from 20.9 to 28.0. Sodium and K concentration ranged from 1.5 to 73 μg g-1 and from 23 to 522 ng g-1, respectively.

Punctuated Evolution of Influenza Virus Neuraminidase (A/H1N1) under Opposing Migration and Vaccination Pressures

PubMed Central

Phillips, J. C.

2014-01-01

Influenza virus contains two highly variable envelope glycoproteins, hemagglutinin (HA) and neuraminidase (NA). The structure and properties of HA, which is responsible for binding the virus to the cell that is being infected, change significantly when the virus is transmitted from avian or swine species to humans. Here we focus first on the simpler problem of the much smaller human individual evolutionary amino acid mutational changes in NA, which cleaves sialic acid groups and is required for influenza virus replication. Our thermodynamic panorama shows that very small amino acid changes can be monitored very accurately across many historic (1945–2011) Uniprot and NCBI strains using hydropathicity scales to quantify the roughness of water film packages. Quantitative sequential analysis is most effective with the fractal differential hydropathicity scale based on protein self-organized criticality (SOC). Our analysis shows that large-scale vaccination programs have been responsible for a very large convergent reduction in common influenza severity in the last century. Hydropathic analysis is capable of interpreting and even predicting trends of functional changes in mutation prolific viruses directly from amino acid sequences alone. An engineered strain of NA1 is described which could well be significantly less virulent than current circulating strains. PMID:25143953

Changing the Impact of Nursing Assistants’ Education in Seniors’ Care: the Living Classroom in Long-Term Care

PubMed Central

Boscart, Veronique M.; d’Avernas, Josie; Brown, Paul; Raasok, Marlene

2017-01-01

Background Evidence-informed care to support seniors is based on strong knowledge and skills of nursing assistants (NAs). Currently, there are insufficient NAs in the workforce, and new graduates are not always attracted to nursing home (NH) sectors because of limited exposure and lack of confidence. Innovative collaborative approaches are required to prepare NAs to care for seniors. Methods A 2009 collaboration between a NH group and a community college resulted in the Living Classroom (LC), a collaborative approach to integrated learning where NA students, college faculty, NH teams, residents, and families engage in a culture of learning. This approach situates the learner within the NH where knowledge, team dynamics, relationships, behaviours, and inter-professional (IP) practice are modelled. Results As of today, over 300 NA students have successfully completed this program. NA students indicate high satisfaction with the LC and have an increased intention to seek employment in NHs. Faculty, NH teams, residents, and families have increased positive beliefs towards educating students in a NH. Conclusion The LC is an effective learning approach with a positive and high impact learning experience for all. The LC is instrumental in contributing to a capable workforce caring for seniors. PMID:28396705

Novel ultra-low temperature co-fired microwave dielectric ceramic at 400 degrees and its chemical compatibility with base metal

PubMed Central

Di, Zhou; Li-Xia, Pang; Ze-Ming, Qi; Biao-Bing, Jin; Xi, Yao

2014-01-01

A novel NaAgMoO4 material with spinel-like structure was synthesized by using the solid state reaction method and the ceramic sample was well densified at an extreme low sintering temperature about 400°C. Rietveld refinement of the crystal structure was performed using FULLPROF program and the cell parameters are a = b = c = 9.22039 Å with a space group F D −3 M (227). High performance microwave dielectric properties, with a permittivity ~7.9, a Qf value ~33,000 GHz and a temperature coefficient of resonant frequency ~−120 ppm/°C, were obtained. From X-ray diffraction (XRD) and Energy Dispersive Spectrometer (EDS) analysis of the co-fired sample, it was found that the NaAgMoO4 ceramic is chemically compatible with both silver and aluminum at the sintering temperature and this makes it a promising candidate for the ultra-low temperature co-fired ceramics technology. Analysis of infrared and THz spectra indicated that dielectric polarizability at microwave region of the NaAgMoO4 ceramic was equally contributed by ionic displasive and electronic polarizations. Its small microwave dielectric permittivity can also be explained well by the Shannon's additive rule. PMID:25099530

Zinc Excess Triggered Polyamines Accumulation in Lettuce Root Metabolome, As Compared to Osmotic Stress under High Salinity

PubMed Central

Rouphael, Youssef; Colla, Giuseppe; Bernardo, Letizia; Kane, David; Trevisan, Marco; Lucini, Luigi

2016-01-01

Abiotic stresses such as salinity and metal contaminations are the major environmental stresses that adversely affect crop productivity worldwide. Crop responses and tolerance to abiotic stress are complex processes for which “-omic” approaches such as metabolomics is giving us a newest view of biological systems. The aim of the current research was to assess metabolic changes in lettuce (Lactuca sativa L.), by specifically probing the root metabolome of plants exposed to elevated isomolar concentrations of NaCl and ZnSO4. Most of the metabolites that were differentially accumulated in roots were identified for stress conditions, however the response was more intense in plants exposed to NaCl. Compounds identified in either NaCl or ZnSO4 conditions were: carbohydrates, phenolics, hormones, glucosinolates, and lipids. Our findings suggest that osmotic stress and the consequent redox imbalance play a major role in determining lettuce root metabolic response. In addition, it was identified that polyamines and polyamine conjugates were triggered as a specific response to ZnSO4. These findings help improve understanding of how plants cope with abiotic stresses. This information can be used to assist decision-making in breeding programs for improving crop tolerance to salinity and heavy metal contaminations. PMID:27375675

[Evaluation of the relapse prevention program for substance abusers called "TAMARPP" at mental health and welfare center].

PubMed

Kondo, Ayumi; Ide, Mihoko; Takahashi, Ikue; Taniai, Tomoko; Miura, Kasumi; Yamaguchi, Akiko; Yotsuji, Naomi; Matsumoto, Toshihiko

2014-04-01

We developed the TAMA mental health and welfare center Relapse Prevention Program (TAMARPP) and evaluated the efficacy of the program. We provided the program for 59 substance abusers at Tokyo Tama Comprehensive Mental Health and Welfare Center, and conducted brief interviews and questionnaire surveys to them four times during eight months follow-up period. The main results were as follows. 1) Most of the subjects were before "hitting bottom". 2) More than half of the subjects continued participating in the program for more than 2 months and their attendance rate was fairly high. 3) Some of the subjects began joining a self-help group as N.A. and A.A. during the follow up period. 4) The mood states of the subjects were gradually improved during the period. 5) About one-third of the subjects abused substance again after two-month' program, but all of them continued to attend the program or a private counseling. Most of their families also continued having support from the center. These findings suggested it was meaningful to have such a friendly and less confrontational program as TAMARPP at our center to provide support for many substance abusers before "hitting bottom" and their families.

Using bibliometrics to analyze the state of academic productivity in US pediatric surgery training programs.

PubMed

Desai, Nidhi; Veras, Laura V; Gosain, Ankush

2018-06-01

The Accreditation Council for Graduate Medical Education (ACGME) Common Program Requirements state that faculty must establish and maintain an environment of inquiry and scholarship. Bibliometrics, the statistical analysis of written publications, assesses scientific productivity and impact. The goal of this study was to understand the state of scholarship at Pediatric Surgery training programs. Following IRB approval, Scopus was used to generate bibliometric profiles for US Pediatric Surgery training programs and faculty. Statistical analyses were performed. Information was obtained for 430 surgeons (105 female) from 48 US training programs. The mean lifetime h-index/surgeon for programs was 14.4 +/- 4.7 (6 programs above 1 SD, 9 programs below 1 SD). The mean 5-yearh-index/surgeon for programs was 3.92 +/- 1.5 (7 programs above 1 SD, 8 programs below 1 SD). Programs accredited after 2000 had a lower lifetime h-index than those accredited before 2000 (p=0.0378). Female surgeons had a lower lifetime h-index (p<0.0001), 5-yearh-index (p=0.0049), and m-quotient (p<0.0001) compared to males. Mean lifetime h-index increased with academic rank (p<0.0001), with no gender differences beyond the assistant professor rank (p=NS). Variability was identified based on institution, gender, and rank. This information can be used for benchmarking the academic productivity of faculty and programs and as an adjunct in promotion/tenure decisions. Original Research. n/a. Copyright © 2018 Elsevier Inc. All rights reserved.

Revised recommendations for iron fortification of wheat flour and an evaluation of the expected impact of current national wheat flour fortification programs.

PubMed

Hurrell, Richard; Ranum, Peter; de Pee, Saskia; Biebinger, Ralf; Hulthen, Lena; Johnson, Quentin; Lynch, Sean

2010-03-01

Iron fortification of wheat flour is widely used as a strategy to combat iron deficiency. To review recent efficacy studies and update the guidelines for the iron fortification of wheat flour. Efficacy studies with a variety of iron-fortified foods were reviewed to determine the minimum daily amounts of additional iron that have been shown to meaningfully improve iron status in children, adolescents, and women of reproductive age. Recommendations were computed by determining the fortification levels needed to provide these additional quantities of iron each day in three different wheat flour consumption patterns. Current wheat flour iron fortification programs in 78 countries were evaluated. When average daily consumption of low-extraction (< or = 0.8% ash) wheat flour is 150 to 300 g, it is recommended to add 20 ppm iron as NaFeEDTA, or 30 ppm as dried ferrous sulfate or ferrous fumarate. If sensory changes or cost limits the use of these compounds, electrolytic iron at 60 ppm is the second choice. Corresponding fortification levels were calculated for wheat flour intakes of < 150 g/day and > 300 g/day. Electrolytic iron is not recommended for flour intakes of < 150 g/day. Encapsulated ferrous sulfate or fumarate can be added at the same concentrations as the non-encapsulated compounds. For high-extraction wheat flour (> 0.8% ash), NaFeEDTA is the only iron compound recommended. Only nine national programs (Argentina, Chile, Egypt, Iran, Jordan, Lebanon, Syria, Turkmenistan, and Uruguay) were judged likely to have a significant positive impact on iron status if coverage is optimized. Most countries use non-recommended, low-bioavailability, atomized, reduced or hydrogen-reduced iron powders. Most current iron fortification programs are likely to be ineffective. Legislation needs updating in many countries so that flour is fortified with adequate levels of the recommended iron compounds.

Slips, lapses and mistakes inthe use of equipment by nurses in an intensive care unit.

PubMed

Ribeiro, Gabriella da Silva Rangel; Silva, Rafael Celestino da; Ferreira, Márcia de Assunção; Silva, Grazielle Rezende da

2016-01-01

Toidentify the occurrence of errors in the use of equipment by nurses working in intensive careandanalyzing them in the framework of James Reason's theory of human error. Qualitative field study in the intensive care unit of a federal hospital in the city of Rio de Janeiro. Observation and interviews were conductedwith eight nurses, from March to December 2014. Content analysis was used for the interviews, as well as the description of the scenes observed. Lapses of memory and attention were identified in the handling of infusion pumps, as well as planning failures during the programming of monitors. Errors cause adverse events that compromise patient safety. The authors propose creation of an instrument for daily checking of equipment, with checks throughout the work process in the programming of infusion pumps and monitors, in order to reduce failures and memory lapses. Identificar a ocorrência de erros na utilização de equipamentos por enfermeiros que atuam na terapia intensiva, analisando-os à luz da teoria do erro humano de James Reason. Pesquisa de campo, qualitativa, na Unidade de Terapia Intensiva de um hospital federal do Rio de Janeiro. Realizou-se observação e entrevista com oito enfermeiros, de março a dezembro de 2014. Aplicou-se análise de conteúdo nas entrevistas e descrição densa nas cenas observadas. Identificaram-se falhas de memória e de atenção no manuseio das bombas infusoras e falhas de planejamento durante a programação dos monitores. Os erros causam eventos adversos que comprometem a segurança do paciente. Propõe-se um instrumento de verificação diária dos equipamentos, com checagens ao longo do processo de trabalho da programação das bombas infusoras e monitores, no intuito de reduzir as falhas e esquecimentos.

An improved model for the calculation of CO2 solubility in aqueous solutions containing Na+, K+, Ca2+, Mg2+, Cl-, and SO42-

USGS Publications Warehouse

Duan, Zhenhao; Sun, R.; Zhu, Chen; Chou, I.-Ming

2006-01-01

An improved model is presented for the calculation of the solubility of carbon dioxide in aqueous solutions containing Na+, K+, Ca2+, Mg2+, Cl-, and SO42- in a wide temperature-pressure-ionic strength range (from 273 to 533 K, from 0 to 2000 bar, and from 0 to 4.5 molality of salts) with experimental accuracy. The improvements over the previous model [Duan, Z. and Sun, R., 2003. An improved model calculating CO2 solubility in pure water and aqueous NaCl solutions from 273 to 533K and from 0 to 2000 bar. Chemical Geology, 193: 257-271] include: (1) By developing a non-iterative equation to replace the original equation of state in the calculation of CO 2 fugacity coefficients, the new model is at least twenty times computationally faster and can be easily adapted to numerical reaction-flow simulator for such applications as CO2 sequestration and (2) By fitting to the new solubility data, the new model improved the accuracy below 288 K from 6% to about 3% of uncertainty but still retains the high accuracy of the original model above 288 K. We comprehensively evaluate all experimental CO2 solubility data. Compared with these data, this model not only reproduces all the reliable data used for the parameterization but also predicts the data that were not used in the parameterization. In order to facilitate the application to CO2 sequestration, we also predicted CO2 solubility in seawater at two-phase coexistence (vapor-liquid or liquid-liquid) and at three-phase coexistence (CO2 hydrate-liquid water-vapor CO2 [or liquid CO2]). The improved model is programmed and can be downloaded from the website http://www.geochem-model.org/programs.htm. ?? 2005 Elsevier B.V. All rights reserved.

Toward more environmentally resistant gas turbines: Progress in NASA-Lewis programs

NASA Technical Reports Server (NTRS)

Lowell, C. E.; Grisaffe, S. J.; Levine, S. R.

1976-01-01

A wide range of programs are being conducted for improving the environmental resistance to oxidation and hot corrosion of gas turbine and power system materials. They range from fundamental efforts to delineate attack mechanisms, allow attack modeling and permit life prediction, to more applied efforts to develop potentially more resistant alloys and coatings. Oxidation life prediction efforts have resulted in a computer program which provides an initial method for predicting long time metal loss using short time oxidation data by means of a paralinear attack model. Efforts in alloy development have centered on oxide-dispersion strengthened alloys based on the Ni-Cr-Al system. Compositions have been identified which are compromises between oxidation and thermal fatigue resistance. Fundamental studies of hot corrosion mechanisms include thermodynamic studies of sodium sulfate formation during turbine combustion. Information concerning species formed during the vaporization of Na2SO4 has been developed using high temperature mass spectrometry.

Nicotine Inhibits Memory CTL Programming

PubMed Central

Sun, Zhifeng; Smyth, Kendra; Garcia, Karla; Mattson, Elliot; Li, Lei; Xiao, Zhengguo

2013-01-01

Nicotine is the main tobacco component responsible for tobacco addiction and is used extensively in smoking and smoking cessation therapies. However, little is known about its effects on the immune system. We confirmed that multiple nicotinic receptors are expressed on mouse and human cytotoxic T lymphocytes (CTLs) and demonstrated that nicotinic receptors on mouse CTLs are regulated during activation. Acute nicotine presence during activation increases primary CTL expansion in vitro, but impairs in vivo expansion after transfer and subsequent memory CTL differentiation, which reduces protection against subsequent pathogen challenges. Furthermore, nicotine abolishes the regulatory effect of rapamycin on memory CTL programming, which can be attributed to the fact that rapamycin enhances expression of nicotinic receptors. Interestingly, naïve CTLs from chronic nicotine-treated mice have normal memory programming, which is impaired by nicotine during activation in vitro. In conclusion, simultaneous exposure to nicotine and antigen during CTL activation negatively affects memory development. PMID:23844169

X-Ray Laser Program for FY93

DTIC Science & Technology

1994-04-25

103070൚I1, Wohinuoan. oc 20603. 1. AGENCY USE ONLY ILaevo NW) j2. REPORT DATE 3. REPORT TYPE AND DATES COVERED I April 25, 1994 4. TITLE AND SUBTITLE 5...effectively use the radiation of the Na pinch to fully ionize this window and thereby reduce its absorption. One of the most attractive methods to...vacancies is explored. The use of thin multiple layers is a potentially promising method of obtaining information about ionization and (possibly) also

CSMP (Continuous System Modeling Program) Modeling of Brushless DC Motors.

DTIC Science & Technology

1984-09-01

Characteristics of Fifteen HP Samarium Cobalt and Ferrite Based brushless DC Ictcrs j. Operated by the Same Power Conditioner ," IEEE Transactions on Pcwer stenM...paratus and Systeis, v. P -Ii-- -ry Demerdash, N.A. and Nehl.T.W., Dynamic Modeling cf Brushless DC Motor-Power Conditioner U if-- fo -- Iec tro me...III _J- _ o 0 NAVAL POSTGRADUATE SCHOOL Monterey, California •S THETIS CSMP MODEL{ING OF BRUSHLESS DC MOTORS by DTIC

No Further Action Decision Document for Site 8 at Alpena Combat Readiness Training Center, Alpena, Michigan.

DTIC Science & Technology

1998-04-01

INSTALLATION RESTORATION PROGRAM No FURTHER REMEDIAL ACTION PLANNED DECISION DOCUMENT FOR SITE 8 FINAL MICHIGAN AIR NATIONAL GUARD ALPENA ...COMBAT READINESS TRAINING CENTER ALPENA , MICHIGAN April 1998 Air National Guard Andrews AFB, Maryland fr r=.~r i^:r^f>^’ m% Approved for public...Document 4. TITLE AND SUBTITLE No Further Action Decision Document for Site 8 at Alpena CRTC, Alpena , MI. 6. AUTHOR(S) N/A 7. PERFORMING

Life Prediction of Fretting Fatigue with Advanced Surface Treatments (Preprint)

DTIC Science & Technology

2006-05-01

surfaces and not the fretting pads. The chosen coatings included DLC, Ni-B, Molybdenum, and Nitride. These 4 coatings, their application to the titanium ...Article Preprint 5a. CONTRACT NUMBER In-house 5b. GRANT NUMBER 4 . TITLE AND SUBTITLE LIFE PREDICTION OF FRETTING FATIGUE WITH ADVANCED SURFACE...TREATMENTS (PREPRINT) 5c. PROGRAM ELEMENT NUMBER N/A 5d. PROJECT NUMBER M02R 5e. TASK NUMBER 30 6 . AUTHOR(S) Patrick J. Golden and Michael

Heat Pipe and Thermal Energy Storage and Corrosion Studies (1988)

DTIC Science & Technology

1989-06-01

of air environment melting and end cap TIG welding [2]. Because of its severity, vacuum thermal cycling of the salt clad capsules between salt eutectic...melting of the salt under an inert gas atmosphere and welding of the specimen capsules by electron beam welding in contrast to previously used methods...electron beam welding . However, no ill effects were believed to have occurred on the overall testing program. Ultrapure fluoride salts LiF, MgF2, NaF

Sea Ice Movements from Synthetic Aperture Radar

DTIC Science & Technology

1981-12-01

correlating these components. B-l8 These correlations are also plotted in figure l1. 5.3.3.2 AUlications of the space correlation. The spatial...aperture radar. To appear in J. of Geophys. Res. Hastings, A. D. Jr., 1971. Surface climate of the Arctic Basin. Report ETL- TR-71-5, Earth Sciences Division...Administration Grant NA50-AA-D-00015, which was funded in part by the Global Atmospheric Research Program and the Office of Climate Dynarics, Divisic

Nuclear Astrophysics At ISAC With DRAGON

DOE Office of Scientific and Technical Information (OSTI.GOV)

D'Auria, John M.

2005-05-24

The unique DRAGON (recoil mass separator) facility is now available to provide measurements of radiative capture reactions involving short-lived exotic reactants which are considered important in explosive stellar scenarios such as novae and X-ray bursts. A description of the first study completed, the 1H(21Na,22Mg){gamma} reaction, will be summarized and updated. In addition, the planned program for DRAGON will be presented along with a summary of the upgrade of the ISAC Radioactive Beams laboratory.

Installation and Implementation of a Comprehensive Groundwater Monitoring Program for the Indian Wells Valley, California

DTIC Science & Technology

2010-04-01

isotopes. Laboratory analysis for general chemistry included Na, Ca, Mg, K, Fe, Cl, HCO3, CO3 , SO4, F, B, NO3, arsenic (As), hardness, alkalinity...used for interpretations within the project. Prior to this effort, a single -location repository for isotopic data related to IWV investigations...canyons of importance to this study (Indian Wells Canyon, Freeman Canyon, and the upgradient canyons of Cow Haven, Sage, and Horse). Single samples

Biopropellant Engine Plume Contamination Program. Volume 1. Chamber Measurements. Phase 1

DTIC Science & Technology

1979-12-01

motor-actuated/linked bipropellant valve manufactured by Moog, Inc. The thrust chambers mechanically attached to the injector were silicide -coated...was NaCI ( sodium chloride); IR camera data were recorded from the side viewport of the lOY chamber. The flowfield viewed with the 8-deg fov lens...100, Contoured Six-Element Splash Plate (0 and 45 deg) 0.0167 (Pc = 150 psia) 100 to 300 100 to 300 0.0006 Silicide -Coated, Columbium Alloy

Operation REDWING-Project 6.4. Airborne Antennas and Phototubes for Determination of Nuclear-Weapon Yield

DTIC Science & Technology

1985-04-01

atmospheric nuclear test program. I ß 1 «I ’ es M 3S ^9 -a 38 ŝ ^^ "^ ^^ "* na R5 58 ^^ *" S8 ’ Rfl 98 ffa K8 »A Ü9 ÜR »A ft& »A KS 9ft KS 93 89...j-U !i ’ 1 1 I \\ ’ r bbp ilpl i’ i; I LLUL IPB"" \\ ::.--=:===:;:=: -^ v~ ] LLLLLL, i

Ground Vehicle Power and Mobility Overview

DTIC Science & Technology

2007-05-30

Program Li-Ion Phosphate (LFP) Cathode Materials Large Format Li-Ion Prismatic Cells and Modules with Integrated Liquid Cooling Integrated Prototype...using porous graphitic material3 4 5 8 5 6 60 W-hr/kg 80-120 W/kg Low Cycle Life LFP cathode Safer Less energetic materials ~ ~ Power Cell 85-120...Thermal Runaway Study Zebra Battery NaNiCl2 (FY08 ATO) Advanced Lead Acid LiFePO4 Cathode Prismatic Lithium-ion batteries and Integrated Liquid Cooling

EA 18G Growler Aircraft (EA 18G)

DTIC Science & Technology

2015-12-01

10051.9 N/A 13186.9 8636.4 11550.1 15672.4 1 APB Breach Confidence Level Confidence Level of cost estimate for current APB: 50% The current...estimate recommendation aims to provide sufficient resources to execute the program under normal conditions, encountering average levels of technical...TY $M) Initial PAUC Development Estimate Changes PAUC Production Estimate Econ Qty Sch Eng Est Oth Spt Total 93.573 4.150 1.442 -0.319 0.947 -0.348

Microwave-Driven Air Plasma Studies for Drag Reduction and Power Extraction in Supersonic Air

DTIC Science & Technology

2004-10-15

called spillage occurs, and the air mass capture decreases (Fig. 3). To avoid performance penalties at off-design Mach numbers, a variable geometry inlet...AND SUBTITLE 5. FUNDING NUMBERS Microwave-Driven Air Plasma Studies for Drag Reduction and Power Extraction in Supersonic Air 6. AUTHOR(S) Richard B...MONITORING AGENCY REPORT NUMBER Air Force Office of Scientific Research/NA (John Schmisseur, Program Manager) 801 N. Randolph St., Room 732 Arlington

NPS Solar Cell Array Tester Cubesat Flight Testing and Integration

DTIC Science & Technology

2014-09-01

with current (I). P V I      (2.1) This is significant because the battery discharge test will not lineup perfectly with Figure 12...accordance with the charging procedures [13]. 3. NPS-SCAT Power Budget A power budget analysis was performed to determine if the NPS-SCAT is self...using procedures developed by Marissa Brummitt, and with the assistance of Adam Hill, NPS-SCAT Program Manager. 1. ELaNa IV Random Vibration Levels

The use of x-ray radiography for measuring mass distributions of Rocket Injectors

DTIC Science & Technology

2013-06-01

successfully applied to diesel injectors , aerated liquid jets and impinging-jet sprays [7-10]. X-ray radiography can be performed using either a...Rocket Injectors 5a. CONTRACT NUMBER N/A 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) S.A. Schumaker, A.L. Kastengren, M.D.A...measurements for injector design. Unfortunately, the mass flow rates typically encountered in rocket engines create sprays with high optical densities

Artificial Neural Network Analysis System

DTIC Science & Technology

2001-02-27

Contract No. DASG60-00-M-0201 Purchase request no.: Foot in the Door-01 Title Name: Artificial Neural Network Analysis System Company: Atlantic... Artificial Neural Network Analysis System 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Powell, Bruce C 5d. PROJECT NUMBER 5e. TASK NUMBER...34) 27-02-2001 Report Type N/A Dates Covered (from... to) ("DD MON YYYY") 28-10-2000 27-02-2001 Title and Subtitle Artificial Neural Network Analysis

The Netted Humanitarian: Improving the Information and Communications Technology Assessment Process for Humanitarian Assistance/Disaster Relief (HA/DR) Missions

DTIC Science & Technology

2013-03-01

NGOs, United Nations-Office for the Coordination of Humanitarian Affairs (UN-OCHA), United Nations-World Food Program (UN-WFP), philanthropic...MISSIONS C5. FUNDING NUMBERS 6. AUTHOR( S ) Christian X. Gutierrez 7. PERFORMING ORGANIZATION NAME( S ) AND ADDRESS(ES) Naval Postgraduate School...Monterey, CA 93943–5000 8. PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING /MONITORING AGENCY NAME( S ) AND ADDRESS(ES) N/A 10. SPONSORING

Ion Source Development for a Compact Proton Beam Writing System II

DTIC Science & Technology

2012-02-17

5c. PROGRAM ELEMENT NUMBER 6. AUTHOR( S ) Jeroen van Kan 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME( S ...N/A 9. SPONSORING/MONITORING AGENCY NAME( S ) AND ADDRESS(ES) AOARD, UNIT 45002, APO, AP, 96338-5002 10. SPONSOR/MONITOR’S ACRONYM( S ) AOARD 11...SPONSOR/MONITOR’S REPORT NUMBER( S ) AOARD-114099 12. DISTRIBUTION/AVAILABILITY STATEMENT Approved for public release; distribution unlimited 13

Organtropic Metastatic Secretomes and Exosomes in Breast Cancer

DTIC Science & Technology

2016-10-01

MD, PhD CONTRACTING ORGANIZATION: Joan & Sanford I Weill Medical College of Cornell University New York, NY 10065 REPORT DATE: October 2016 TYPE...STATEMENT: Approved for Public Release; Distribution Unlimited The views, opinions and/or findings contained in this report are those of the author( s ) and...Cancer 5b. GRANT NUMBER N/A 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR( S ) 5d. PROJECT NUMBER David Lyden, MD, PhD, Ayuko Hoshino, PhD, Irina Matei, PhD

The War Against Generational Poverty: A Comparative Study of Conditional Cash Transfer Programs in Brazil, Chile, and Jamaica

DTIC Science & Technology

2014-12-01

Government . IRB Protocol number ____N/A____. 12a. DISTRIBUTION / AVAILABILITY STATEMENT Approved for public release; distribution is unlimited...control many of the major industries. Jamaica is also a free-market economy, but the government takes a fairly active role in attracting business to the...Polanyi countered Smith’s idea that markets arose spontaneously. Polanyi argued that governments create markets and direct and regulate them to protect

Documentation and User’s Manual for the Visual Detection Simulator (VDS) .

DTIC Science & Technology

1979-04-01

BUMEI) ZF51..524.004-2011 CONTROLLING OFFICE NAME AND ADDRESS 12 REPORT DATE Na al Mhedical Research and vel()chp ,ncIt Command .\\pril 1979 Nationa...Mediral Research and Development Command ZF51.524.004 --2011 Approved by ,3eleased by Ashton Graybiel, M.D. Captain R. E. Mitchel, MC, USN I Assistant for...Scientific Programs Commanrding Officer /April 1379 /- Naval Aerospace Medical Research Laboratory Naval Air Station Pensacola, Florida 32508 7

Hyponatremia in liver cirrhosis: pathophysiological principles of management.

PubMed

Castello, L; Pirisi, M; Sainaghi, P P; Bartoli, E

2005-02-01

Hyponatremia is common in cirrhosis, where it impairs encephalopathy. It could be either due to excess water, or reduced Na, or a combination of both. The diagnosis can be established with clinical skills aided by simple data like weight, blood pressure and plasma electrolytes. The quantitative estimates of the water surfeit or solute deficit, easily performed with simple formulas and measurements, guide accurate and programmed treatment procedures, avoiding the occurrence of the ominous central pontine myelinolysis.

Dual RNA-seq reveals no plastic transcriptional response of the coccidian parasite Eimeria falciformis to host immune defenses.

PubMed

Ehret, Totta; Spork, Simone; Dieterich, Christoph; Lucius, Richard; Heitlinger, Emanuel

2017-09-05

Parasites can either respond to differences in immune defenses that exist between individual hosts plastically or, alternatively, follow a genetically canalized ("hard wired") program of infection. Assuming that large-scale functional plasticity would be discernible in the parasite transcriptome we have performed a dual RNA-seq study of the lifecycle of Eimeria falciformis using infected mice with different immune status as models for coccidian infections. We compared parasite and host transcriptomes (dual transcriptome) between naïve and challenge infected mice, as well as between immune competent and immune deficient ones. Mice with different immune competence show transcriptional differences as well as differences in parasite reproduction (oocyst shedding). Broad gene categories represented by differently abundant host genes indicate enrichments for immune reaction and tissue repair functions. More specifically, TGF-beta, EGF, TNF and IL-1 and IL-6 are examples of functional annotations represented differently depending on host immune status. Much in contrast, parasite transcriptomes were neither different between Coccidia isolated from immune competent and immune deficient mice, nor between those harvested from naïve and challenge infected mice. Instead, parasite transcriptomes have distinct profiles early and late in infection, characterized largely by biosynthesis or motility associated functional gene groups, respectively. Extracellular sporozoite and oocyst stages showed distinct transcriptional profiles and sporozoite transcriptomes were found enriched for species specific genes and likely pathogenicity factors. We propose that the niche and host-specific parasite E. falciformis uses a genetically canalized program of infection. This program is likely fixed in an evolutionary process rather than employing phenotypic plasticity to interact with its host. This in turn might limit the potential of the parasite to adapt to new host species or niches, forcing it to coevolve with its host.

Pathway out of Poverty: A Values-Based College-Community Partnership to Improve Long-Term Outcomes of Underrepresented Students

PubMed Central

Boyd, Jamie Kamailani; Kuuleialoha Kamaka, Sharmayne A.; Braun, Kathryn L.

2015-01-01

Background Native Hawaiians, representing 25% of Hawai‘i’s population, suffer socioeconomic and health strains as evidenced by overrepresentation in low-wage jobs without health insurance and a higher prevalence of chronic disease compared with Hawai‘i’s other ethnic groups. Native Hawaiians are more likely to attend community colleges than 4-year colleges and have high dropout rates. Objective To describe a culturally relevant, community-based action research approach to build a program to keep Hawaiians in college to advance career options and improve long-term health and socioeconomic outcomes. Methods Culturally relevant approaches that depended on participation from a variety of community partners were used to evaluate needs and design interventions. Results The Pathway Out of Poverty Program uses Hawaiian values and traditions of healthy living to lead students through a nursing pathway from nurse aide (NA) to licensed practical nurse (LPN) to registered nurse (RN), with inherent increases in wage-earning potential. In the first 3.5 years, 150 students enrolled in NA training, and 135 students (90%) graduated and were certified. Of the 135, 77 (57%) transitioned to higher education and 79% transitioned to jobs that offered health insurance (20% were in both groups). Of the 77 entering higher education, 33 (43%) aimed for a degree in nursing. Students expressed growing interest in health promotion for themselves, family members, and others. Conclusion Community partners were key to developing a successful community college-based Pathway Program to help marginalized and other underrepresented students move from low-wage to living-wage jobs and improve their long-term health outcomes. PMID:22643785

The Link between low H2O Activity and Chloride Brines in High-Grade Metamorphism - A Status Report

NASA Astrophysics Data System (ADS)

Manning, C. E.; Newton, R. C.

2006-12-01

High-grade metamorphic mineral assemblages typically record low activity of H2O (aH2O) at peak conditions. Substantial debate has centered on whether low aH2O requires the presence of a hydrous melt or of a fluid phase. Lowering aH2O in a fluid phase by CO2 is problematic because (1) at requisite compositions and observed fO2, graphite should be stable but is not observed; and (2) H2O-CO2 fluids are poor solvents for many of the components observed to be mobile at the amphibolite-granulite transition. In contrast, chloride brines are more likely to be responsible for reduced aH2O where a fluid phase is present (e.g., Newton et al., 1998, Precambrian Res., 91, 41). However, the properties of such brines are poorly understood at high P and T. We are addressing this problem through a program of experimental measurement of mineral solubilities in NaCl-H2O solutions at high P and T. Results indicate that, at 800°C and 10 kbar, solubilities of volatile-bearing, congruently soluble Ca minerals increase strongly with NaCl to halite saturation. At XNaCl = 0.3 (assuming full dissociation), Ca mole fractions in solutions increase as follows: 0.0012 (apatite), 0.0075 (fluorite), 0.0107 (calcite), 0.0513 (anhydrite). Because solubilities of F, CO2, and SO4 will increase correspondingly, H2O-NaCl brines will promote significant volatile transfer. By contrast, oxides exhibit variable behavior. At the same P and T, quartz solubility decreases monotonically with increasing NaCl, whereas corundum, hematite, wollastonite, diopside, and grossular mole fractions all increase to maxima at low to moderate XNaCl, and then decline to halite saturation. These results indicate that SiO2 does not ineract with NaCl, whereas the dissolution of the other minerals involves consumption of NaCl by solutes to a greater extent than H2O. Notably, solubility of Al is strongly enhanced in NaCl-H2O with SiO2 ± CaO. It is unlikely that all instances of low aH2O in high-grade metamorphic rocks are explained by a single mechanism; however, our results clearly demonstrate that, where present, a low- aH2O chloride brine can act as a powerful solvent in the lower crust, even at very low water-rock ratios.

XWVG: A Waveguide Program for Trilinear Tropospheric Ducts. Computer Program for Calculating the Signal Levels of EM (Electromagnetic) Waves Propagating over Seawater.

DTIC Science & Technology

1983-06-30

176 .- 441 CALL CADU (FK22A.FK22E.XAA.YAE.YRA.APF) 442 TF(LPCVR.EC.2) TIPFK 443 7AAuFK12A*tOTA2*QRAl 444 7AEwFKj2E(PTE?,tQREl 445 7PAnFK22A’flTA2.CRA2...470 YAE.023E2.flQ33Ei 471 WBA=DC23A2*033A1 472 W8F.IPC23E2+Q33El 473 CALL CADU (YPA.YRE*XAA*XAEaWBA*YQE) 474 VAA.SC-NA2*Ct.D(O22A2*Q12A2 475 WA~wDtC22F2

Performance evaluation of advanced battery technologies for electric vehicle applications

NASA Astrophysics Data System (ADS)

Deluca, W. H.; Tummillo, A. F.; Kulaga, J. E.; Webster, C. E.; Gillie, K. R.; Hogrefe, R. L.

1990-01-01

At the Argonne Analysis and Diagnostic Laboratory, advanced battery technology evaluations are performed under simulated electric vehicle operating conditions. During 1989 and the first quarter of 1990, single cell and multicell modules from seven developers were examined for the Department of Energy and Electric Power Research Institute. The results provide battery users, developers, and program managers with an interim measure of the progress being made in battery R&D programs, a comparison of battery technologies, and a source of basic data for modeling and continuing R&D. This paper summarizes the performance and life characterizations of two single cells and seven 3- to 960-cell modules that encompass six technologies (Na/S, Ni/Fe, Ni/Cd, Ni-metal hydride, lead-acid, and Zn/Br).

Apparatus for rapid adjustment of the degree of alignment of NMR samples in aqueous media: verification with residual quadrupolar splittings in (23)Na and (133)Cs spectra.

PubMed

Kuchel, Philip W; Chapman, Bogdan E; Müller, Norbert; Bubb, William A; Philp, David J; Torres, Allan M

2006-06-01

NMR spectra of (23)Na(+) and (133)Cs(+) in gelatine in a silicone rubber tube that was stretched to various extents showed remarkably reproducible resonance multiplicity. The relative intensities of the components of the split peaks had ratios, 3:4:3, and 7:12:15:16:15:12:7, respectively, that conformed with those predicted using a Mathematica program. The silicone-rubber tube was sealed at its lower end by a small rubber stopper and placed inside a thick-walled glass tube. Gelatine was injected in solution into the silicone tube and 'set' by cooling below 30 degrees C. A plastic thumb-screw held the silicone tube at various degrees of extension, up to approximately 2-fold. After constituting the gel in buffers containing NaCl and CsCl, both (23)Na and (133)Cs NMR spectroscopy revealed that after stretching the initial single Lorentzian line was split into a well-resolved triplet and a heptet, respectively. This was interpreted as being due to coupling between the electric quadrupoles of the nuclei and the average electric field gradient tensor of the collagen molecules of gelatine; these molecules became progressively more aligned in the direction of the main magnetic field, B(0), of the vertical bore magnet, as the gel was stretched. This apparatus provides a simple way of demonstrating fundamental physical characteristics of quadrupolar cations, some characteristics of gelatine under stretching, and a way to invoke static distortion of red blood cells. It should be useful with these and other cell types, for studies of metabolic and membrane transport characteristics that may change when the cells are distorted, and possibly for structural studies of macromolecules.

Apparatus for rapid adjustment of the degree of alignment of NMR samples in aqueous media: Verification with residual quadrupolar splittings in 23Na and 133Cs spectra

NASA Astrophysics Data System (ADS)

Kuchel, Philip W.; Chapman, Bogdan E.; Müller, Norbert; Bubb, William A.; Philp, David J.; Torres, Allan M.

2006-06-01

NMR spectra of 23Na + and 133Cs + in gelatine in a silicone rubber tube that was stretched to various extents showed remarkably reproducible resonance multiplicity. The relative intensities of the components of the split peaks had ratios, 3:4:3, and 7:12:15:16:15:12:7, respectively, that conformed with those predicted using a Mathematica program. The silicone-rubber tube was sealed at its lower end by a small rubber stopper and placed inside a thick-walled glass tube. Gelatine was injected in solution into the silicone tube and 'set' by cooling below 30 °C. A plastic thumb-screw held the silicone tube at various degrees of extension, up to ˜2-fold. After constituting the gel in buffers containing NaCl and CsCl, both 23Na and 133Cs NMR spectroscopy revealed that after stretching the initial single Lorentzian line was split into a well-resolved triplet and a heptet, respectively. This was interpreted as being due to coupling between the electric quadrupoles of the nuclei and the average electric field gradient tensor of the collagen molecules of gelatine; these molecules became progressively more aligned in the direction of the main magnetic field, B0, of the vertical bore magnet, as the gel was stretched. This apparatus provides a simple way of demonstrating fundamental physical characteristics of quadrupolar cations, some characteristics of gelatine under stretching, and a way to invoke static distortion of red blood cells. It should be useful with these and other cell types, for studies of metabolic and membrane transport characteristics that may change when the cells are distorted, and possibly for structural studies of macromolecules.

The corrosion of titanium in alkaline peroxide bleach liquors

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wyllie, W.E. II; Brown, B.E.; Duquette, D.J.

1994-12-31

An experimental program to determine the effects of hydrogen peroxide (H{sub 2}O{sub 2}) and of potential corrosion inhibitors on the corrosion behavior of titanium has been developed. Corrosion rates less than 0.25 mm/y were observed in laboratory bleach liquor at pH 12 to which 5 g/l of H{sub 2}O{sub 2} were added. At pH 13, with 10 g/l H{sub 2}O{sub 2}, the corrosion rates were unacceptably high in both sodium hydroxide (NaOH) and laboratory bleach liquor solutions (>8.38 mm/y). The preliminary results of inhibitor studies indicated that the addition of 3.7 g/l sodium silicate or 0.01 g/l calcium nitrate (Ca(NO{submore » 3}){sub 2}) effectively inhibited the corrosion of titanium exposed to 5 g/l of H{sub 2}O{sub 2} in NaOH solutions of pH 12. It was also found that in simulated paper mill chemistries, i.e., basic solutions containing 3.7 g/l sodium silicate and 0.6 g/l EDTA (ethylenediaminetetraacetic acid), corrosion rates increased markedly with the addition of 5 g/l H{sub 2}O{sub 2}. However, subsequent additions of peroxide resulted in corrosion rates which were even lower than those found in NaOH. This is believed to be due to the formation of a black scale on the surface of the sample. The addition of magnesium sulfate (MgSO{sub 4}) in the 0.1--0.5 g/l range also was shown to inhibit corrosion in the NaOH solution, but only after prior exposure to H{sub 2}O{sub 2}.« less

ChemStable: a web server for rule-embedded naïve Bayesian learning approach to predict compound stability.

PubMed

Liu, Zhihong; Zheng, Minghao; Yan, Xin; Gu, Qiong; Gasteiger, Johann; Tijhuis, Johan; Maas, Peter; Li, Jiabo; Xu, Jun

2014-09-01

Predicting compound chemical stability is important because unstable compounds can lead to either false positive or to false negative conclusions in bioassays. Experimental data (COMDECOM) measured from DMSO/H2O solutions stored at 50 °C for 105 days were used to predicted stability by applying rule-embedded naïve Bayesian learning, based upon atom center fragment (ACF) features. To build the naïve Bayesian classifier, we derived ACF features from 9,746 compounds in the COMDECOM dataset. By recursively applying naïve Bayesian learning from the data set, each ACF is assigned with an expected stable probability (p(s)) and an unstable probability (p(uns)). 13,340 ACFs, together with their p(s) and p(uns) data, were stored in a knowledge base for use by the Bayesian classifier. For a given compound, its ACFs were derived from its structure connection table with the same protocol used to drive ACFs from the training data. Then, the Bayesian classifier assigned p(s) and p(uns) values to the compound ACFs by a structural pattern recognition algorithm, which was implemented in-house. Compound instability is calculated, with Bayes' theorem, based upon the p(s) and p(uns) values of the compound ACFs. We were able to achieve performance with an AUC value of 84% and a tenfold cross validation accuracy of 76.5%. To reduce false negatives, a rule-based approach has been embedded in the classifier. The rule-based module allows the program to improve its predictivity by expanding its compound instability knowledge base, thus further reducing the possibility of false negatives. To our knowledge, this is the first in silico prediction service for the prediction of the stabilities of organic compounds.

Nutritional composition of school meals serving children from 7 to 36 months of age in municipal day-care centres in the metropolitan area of Curitiba, Paraná, Brazil.

PubMed

Retondario, Anabelle; Silva, Débora Letícia Frizzi; Salgado, Silvana Magalhães; Alves, Márcia Aurelina de Oliveira; Ferreira, Sila Mary Rodrigues

2016-06-01

The Brazilian National School Feeding Program (PNAE) seeks to meet student's nutritional needs during the period they remain in school. This study aimed to determine the nutritional composition of meals provided in municipal day-care centres serving children of 7-11 months (group A) and 12-36 months (group B) of age and to compare observed values with the PNAE's and dietary reference intakes' (DRI) recommendations. This cross-sectional study was conducted in 4 day-care centres in the metropolitan area of Curitiba, Paraná, Brazil, between June and November 2013. Food samples of six daily meals were collected during 20 non-consecutive days, totalling 120 samples. For each meal, average served and consumed portions were submitted for laboratory analysis of moisture, ash, proteins, lipids, carbohydrates, dietary fibre, Na, Ca and Fe and compared with the PNAE's and DRI's values. No statistically significant difference was found between age groups (P=0·793) regarding portion sizes and nutritional composition. The same menu was offered to both groups in 95 % of the meals (n 114), although the groups' nutritional needs were different. For group A, served meals met PNAE's recommendations for energy, carbohydrates, proteins, Na and Ca content, and consumed portions provided 70 % of the nutritional needs for carbohydrates, proteins and Ca. For group B, served portions complied with the PNAE's values for proteins, Na and Ca. Proteins and Na reached 70 % of the nutritional needs when consumed food was evaluated. School feeding in day-care centres partially meet PNAE's guidelines and children's nutritional requirements, contradicting the primary objective established by the national programme.

Exogenous trehalose largely alleviates ionic unbalance, ROS burst, and PCD occurrence induced by high salinity in Arabidopsis seedlings

PubMed Central

Yang, Lei; Zhao, Xiaoju; Zhu, Hong; Paul, Matthew; Zu, Yuangang; Tang, Zhonghua

2014-01-01

Trehalose (Tre) has been reported to play a critical role in plant response to salinity and the involved mechanisms remain to be investigated in detail. Here, the putative roles of Tre in regulation of ionic balance, cellular redox state, cell death were studied in Arabidopsis under high salt condition. Our results found that the salt-induced restrictions on both vegetative and reproductive growth in salt-stressed plants were largely alleviated by exogenous supply with Tre. The microprobe analysis of ionic dynamics in the leaf and stem of florescence highlighted the Tre ability to retain K and K/Na ratio in plant tissues to improve salt tolerance. The flow cytometry assay of cellular levels of reactive oxygen species and programmed cell death displayed that Tre was able to antagonized salt-induced damages in redox state and cell death and sucrose did not play the same role with Tre. By comparing ionic distribution in leaf and inflorescence stem (IS), we found that Tre was able to restrict Na transportation to IS from leaves since that the ratio of Na accumulation in leaves relative to IS was largely improved due to Tre. The marked decrease of Na ion and improved sucrose level in IS might account for the promoted floral growth when Tre was included in the saline solution. At the same time, endogenous soluble sugars and antioxidant enzyme activities in the salt-stressed plants were also elevated by Tre to counteract high salt stress. We concluded that Tre could improve Arabidopsis salt resistance with respect to biomass accumulation and floral transition in the means of regulating plant redox state, cell death, and ionic distribution. PMID:25400644

Experiences with radiation portal detectors for international rail transport

NASA Astrophysics Data System (ADS)

Stromswold, D. C.; McCormick, K.; Todd, L.; Ashbaker, E. D.; Evans, J. C.

2006-08-01

Radiation detectors monitored trains at two international borders to evaluate the performance of NaI(Tl) and plastic (polyvinyltoluene: PVT) gamma-ray detectors to characterize rail cargo. The detectors included a prototype NaI(Tl) radiation-portal-monitor panel having four large detectors (10-cm × 10-cm × 41-cm) and a PVT panel with a 41 cm × 173 cm × 3.8-cm detector. Spectral data from the NaI(Tl) and PVT detectors were recorded. Of particular emphasis was the identification of naturally occurring radioactive material (NORM) and the resultant frequency of nuisance alarms. For rail monitoring, the difficulty in stopping trains to perform secondary inspection on alarming cars creates a need for reliable identification of NORM during initial screening. Approximately 30 trains were monitored, and the commodities in individual railcars were ascertained from manifest information. At one test site, the trains carried inter-modal containers that had been unloaded from ships, and at the other site, the trains contained bulk cargo in tanker cars and hopper cars or individual items in boxcars or flatbeds. NORM encountered included potash, liquefied petroleum gas, fireworks, televisions, and clay-based products (e.g., pottery). Analysis of the spectral data included the use of the template-fitting portion of the program GADRAS developed at Sandia National Laboratories. For most of the NORM, the NaI(Tl) data produced a correct identification of the radionuclides present in the railcars. The same analysis was also used for PVT data in which the spectral information (no peaks but only gradual spectral changes including Compton edges) was limited. However, the PVT analysis provided correct identification of 40K and 226Ra in many cases.

Environmental fatigue of an Al-Li-Cu alloy. Part 1: Intrinsic crack propagation kinetics in hydrogenous environments

NASA Technical Reports Server (NTRS)

Piascik, Robert S.; Gangloff, Richard P.

1991-01-01

Deleterious environmental effects on steady-state, intrinsic fatigue crack propagation (FCP) rates (da/dN) in peak aged Al-Li-Cu alloy 2090 are established by electrical potential monitoring of short cracks with programmed constant delta K and K(sub max) loading. The da/dN are equally unaffected by vacuum, purified helium, and oxygen but are accelerated in order of decreasing effectiveness by aqueous 1 percent NaCl with anodic polarization, pure water vapor, moist air, and NaCl with cathodic polarization. While da/dN depends on delta K(sup 4.0) for the inert gases, water vapor and chloride induced multiple power-laws, and a transition growth rate 'plateau'. Environmental effects are strongest at low delta K. Crack tip damage is ascribed to hydrogen embrittlement because of the following: (1) accelerated da/dN due to part-per-million levels of H2O without condensation; (2) impeded molecular flow model predictions of the measured water vapor pressure dependence of da/dN as affected by mean crack opening; (3) the lack of an effect of film-forming O2; (4) the likelihood for crack tip hydrogen production in NaCl, and (5) the environmental and delta K-process zone volume dependencies of the microscopic cracking modes. For NaCl, growth rates decrease with decreasing loading frequency, with the addition of passivating Li2CO3, and upon cathodic polarization. These variables increase crack surface film stability to reduce hydrogen entry efficiency. The hydrogen environmental FCP resistance of 2090 is similar to other 2000 series alloys and is better than 7075.

HIV-1 drug resistance in recently HIV-infected pregnant mother's naïve to antiretroviral therapy in Dodoma urban, Tanzania.

PubMed

Vairo, Francesco; Nicastri, Emanuele; Liuzzi, Giuseppina; Chaula, Zainab; Nguhuni, Boniface; Bevilacqua, Nazario; Forbici, Federica; Amendola, Alessandra; Fabeni, Lavinia; De Nardo, Pasquale; Perno, Carlo Federico; Cannas, Angela; Sakhoo, Calistus; Capobianchi, Maria Rosaria; Ippolito, Giuseppe

2013-09-21

HIV resistance affects virological response to therapy and efficacy of prophylaxis in mother-to-child-transmission. The study aims to assess the prevalence of HIV primary resistance in pregnant women naïve to antiretrovirals. Cross sectional baseline analysis of a cohort of HIV + pregnant women (HPW) enrolled in the study entitled Antiretroviral Management of Antenatal and Natal HIV Infection (AMANI, peace in Kiswahili language). The AMANI study began in May 2010 in Dodoma, Tanzania. In this observational cohort, antiretroviral treatment was provided to all women from the 28th week of gestation until the end of the breastfeeding period. Baseline CD4 cell count, viral load and HIV drug-resistance genotype were collected. Drug-resistance analysis was performed on 97 naïve infected-mothers. The prevalence of all primary drug resistance and primary non-nucleoside reverse-transcriptase inhibitors resistance was 11.9% and 7.5%, respectively. K103S was found in two women with no M184V detection. HIV-1 subtype A was the most commonly identified, with a high prevalence of subtype A1, followed by C, D, C/D recombinant, A/C recombinant and A/D recombinant. HIV drug- resistance mutations were detected in A1 and C subtypes. Our study reports an 11.9% prevalence rate of primary drug resistance in naïve HIV-infected pregnant women from a remote area of Tanzania. Considering that the non-nucleoside reverse-transcriptase inhibitors are part of the first-line antiretroviral regimen in Tanzania and all of Africa, resistance surveys should be prioritized in settings where antiretroviral therapy programs are scaled up.

Modifying Earth's Insolation with Aerosols: Reflectance and Polarization Properties of Candidate Particulate Materials

NASA Astrophysics Data System (ADS)

Nelson, R. M.; Boryta, M. D.; Hapke, B. W.; Manatt, K. S.; Shkuratov, Y.; Vandervoort, K.; Vides, C.; Quinones, J.

2017-12-01

We report reflectance phase curves of selected materials, including several that, if distributed as particulate aerosols, might regulate solar insolation and hence reduce Earth's surface temperature. (See e.g. Teller et al., 1997). We have identified several materials that have phase functions that are remarkably backscattering at very small phase angles (Nelson et al., 2017). When these materials are of appropriately small particle size and in the form of dispersed discrete random media, they are highly reflective at ultraviolet and visual wavelengths. Particles of less than 0.5 microns in diameter are transparent in the infrared. The most promising of these is the mineral halite (NaCl). NaCl and its sister materials exhibit this property due to their simple cubic crystal structure. In crystalline form they are `corner cube' reflectors similar to those on bicycle reflectors used throughout the world, and in arrays deployed by astronauts on the Moon for precise distance determination. As aerosols distributed in relatively small quantities, NaCl might reduce the solar forcing function by several W/m2, the amount estimated by the IPCC to be the anthropogenic contribution to global warming. Furthermore, NaCl is environmentally benign and, as a particulate aerosol, it would have short residence time in the atmosphere. With great trepidation, we suggest potential use in these areas: Temporary regional application to mitigate short-term, life-threatening conditions in areas where extreme temperature events are expected on timescales of days, and Global application for immediate relief during a near-term transition period to an atmosphere that is generally free of anthropogenic greenhouse gas. We offer this as a temporary relief measure and not a solution, somewhat analogous to the application of morphine in a medical situation. This work partially supported by NASA's Cassini Orbiter Program

Experiences with radiation portal detectors for international rail transport

DOE Office of Scientific and Technical Information (OSTI.GOV)

Stromswold, David C.; McCormick, Kathleen R.; Todd, Lindsay C.

Radiation detectors monitored trains at two international borders to evaluate the performance of NaI(Tl) and plastic (polyvinyltoluene: PVT) gamma-ray detectors to characterize rail cargo. The detectors included a prototype NaI(Tl) radiation-portal-monitor panel having four large detectors (10-cm × 10-cm × 41-cm) and a PVT panel with a 41 cm × 173 cm × 3.8-cm detector. Spectral data from the NaI(Tl) and PVT detectors were recorded. Of particular emphasis was the identification of naturally occurring radioactive material (NORM) and the resultant frequency of nuisance alarms. For rail monitoring, the difficulty in stopping trains to perform secondary inspection on alarming cars createsmore » a need for reliable identification of NORM during initial screening. Approximately 30 trains were monitored, and the commodities in individual railcars were ascertained from manifest information. At one test site the trains carried inter-modal containers that had been unloaded from ships, and at the other site the trains contained bulk cargo or individual items in boxcars or flatbeds. NORM encountered included potash, liquefied petroleum gas, fireworks, televisions, and clay-based products (e.g., pottery). Analysis of the spectral data included the use of the template-fitting program GADRAS/FitToDB from Sandia National Laboratories. For much of the NORM the NaI(Tl) data produced a correct identification of the radionuclides present in the railcars. The same analysis was also used for PVT data in which the spectral information (no peaks but only gradual spectral changes including Compton edges) was limited. However, the PVT analysis provided correct identification of 40K and 226Ra in many cases.« less

Physiological and leaf metabolome changes in the xerohalophyte species Atriplex halimus induced by salinity.

PubMed

Bendaly, Alia; Messedi, Dorsaf; Smaoui, Abderrazak; Ksouri, Riadh; Bouchereau, Alain; Abdelly, Chedly

2016-06-01

Atriplex halimus is a xerohalophyte plant, which could be used as cash crops. This plant was integrated in Tunisian government programs the aim of which is to rehabilitate saline areas and desert. To investigate its strategies involved in salt tolerance, A. halimus was grown hydroponically under controlled conditions with increasing salinity. Plants were harvested and analyzed after 60 days of treatment. The biomass of A. halimus increased by moderate salinity and decreased significantly at high salinity compared to control plants at 400 mM. Despite of the large amounts of Na(+) observed in the leaves of Atriplex plants, leaf water contents and leaf succulence kept on increasing in treated plants and decreased over 150 mM NaCl. This confirmed the compartmentation and the efficient contribution of Na(+) in the osmotic adjustment. Analysis of the metabolic profiles showed an accumulation of carbohydrates and amino acids. The leaf tissues preferentially stored proline, α alanine and sucrose. Increasing NaCl levels were also accompanied by a significant accumulation of malate in leaves. Involvement of these solutes in osmotic adjustment was considered low. Nevertheless, they seemed to have an important role in controlling photosynthesis which capacity was enhanced by low salinity and decreased with increasing salinity (evaluated by actual photochemical efficiency of photosystem II and chlorophyll contents). The unchanged maximum photochemical efficiency of photosystem II accompanied by the increase of the non-photochemical quenching, the enhancement of the total antioxidant activity and the decrease of the malondialdehyde contents in leaves showed efficient protection of membranes and photosystem II from photo-oxidative damage. This protection seemed to be attributed to proline and sucrose largely accumulated in leaves treated with salt. Copyright © 2016 Elsevier Masson SAS. All rights reserved.

CBRN Decontamination: Multiservice Tactics, Techniques, and Procedures for Chemical, Biological, Radiological, and Nuclear Decontamination

DTIC Science & Technology

2006-04-01

b. Principles of Decontamination Operations. Decontaminate immediately for an agent on the skin . Perform higher levels of decontamination as a...the mask and hood with paper towels or rags. NOTE: Cool, soapy water is not as effective for removing contamination, but it can be used if you scrub ...N/A N/A 5 N/A Sponge, cellulose II Each As required N/A N/A N/A N/A 2 N/A 4 6 Brush, scrub II Each As required N/A N/A N/A N/A 2 N/A 2 N/A Towels

Development and validation of the nasopharyngeal cancer scale among the system of quality of life instruments for cancer patients (QLICP-NA V2.0): combined classical test theory and generalizability theory.

PubMed

Wu, Jiayuan; Hu, Liren; Zhang, Gaohua; Liang, Qilian; Meng, Qiong; Wan, Chonghua

2016-08-01

This research was designed to develop a nasopharyngeal cancer (NPC) scale based on quality of life (QOL) instruments for cancer patients (QLICP-NA). This scale was developed by using a modular approach and was evaluated by classical test and generalizability theories. Programmed decision procedures and theories on instrument development were applied to create QLICP-NA V2.0. A total of 121 NPC inpatients were assessed using QLICP-NA V2.0 to measure their QOL data from hospital admission until discharge. Scale validity, reliability, and responsiveness were evaluated by correlation, factor, parallel, multi-trait scaling, and t test analyses, as well as by generalizability (G) and decision (D) studies of the generalizability theory. Results of multi-trait scaling, correlation, factor, and parallel analyses indicated that QLICP-NA V2.0 exhibited good construct validity. The significant difference of QOL between the treated and untreated NPC patients indicated a good clinical validity of the questionnaire. The internal consistency (α) and test-retest reliability coefficients (intra-class correlations) of each domain, as well as the overall scale, were all >0.70. Ceiling effects were not found in all domains and most facets, except for common side effects (24.8 %) in the domain of common symptoms and side effects, tumor early symptoms (27.3 %) and therapeutic side effects (23.2 %) in specific domain, whereas floor effects did not exist in each domain/facet. The overall changes in the physical and social domains were significantly different between pre- and post-treatments with a moderate effective size (standard response mean) ranging from 0.21 to 0.27 (p < 0.05), but these changes were not obvious in the other domains, as well as in the overall scale. Scale reliability was further confirmed by G coefficients and index of dependability, with more exact variance components based on generalizability theory. QLICP-NA V2.0 exhibited reasonable degrees of validity, reliability, and responsiveness. However, this scale must be further improved before it can be used as a practical instrument to evaluate the QOL of NPC patients in China.

Air Force Dynamic Mechanical Analysis of NATO Round Robin Propellant Testing for Development of AOP-4717

DTIC Science & Technology

2015-09-23

Round Robin Propellant Testing for Development of AOP-4717 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S...area code) N/A Standard Form 298 (Rev. 8-98) Prescribed by ANSI Std. 239.18 0 Air Force Dynamic Mechanical Analysis of NATO Round Robin ...the clamps are tight at the coldest temperature. • Long tests such as the frequency sweep sequences prescribed in this round robin may be

Design of a Microprogram Control Unit with Concurrent Error Detection.

DTIC Science & Technology

1984-08-01

I fxoot Office of Naval Research N/A N00039-80-C-0556 ta. ADDRESS (City. St.. and ZIP Cod 10. SOURCE OF FUNOING N0. -PROGRAM PROJECT TASK WORK UNIT...However, the CED concept is mainly applied to various codes data transmission, and simple functional units, such as arithmetic units. Little work has...been done in the control unit area. Previous work is primarily in the use of clanical self-checking circuits, using bit slicin& parity, and m-out-of-n

The Army’s Ground Combat Vehicle Program and Alternatives

DTIC Science & Technology

2013-04-01

the M2A3 Bradley IFV used in Iraq, which includes reactive armor and underbelly armor. Weighta Number of Vehicle (Tons) Passengers Ground Combat...RCWS = remotely controlled weapon station; n.a. = not applicable. a. Version of the M2A3 Bradley IFV used in Iraq, which includes reactive armor and...trade-offs that the Army made to reduce the average procurement unit cost to $13.5 million (in 2013 dollars). b. Version of the M2A3 Bradley IFV used

An RCT of Nurse Coaching vs. Herbal CAM for Soldier Weight Reduction

DTIC Science & Technology

2015-12-08

Coaching vs. Herbal CAM for Soldier Weight Reduction 5b. GRANT NUMBER HT9404-12-1-TS03 5c. PROGRAM ELEMENT NUMBER N/A 6. AUTHOR(S) 5d...coaching intervention and an herbal supplement for Service Member (SM) weight reduction over a 12-week period to evaluate their effectiveness...Title of Research Study or Evidence-Based Practice (EBP) Project An RCT of Nurse Coaching vs. Herbal CAM for Soldier Weight Reduction Period of Award

Exploring Electrical and Magnetic Resonances from Coherently Correlated Long-Lived Radical Pairs towards Development of Negative Refractive-Index Materials

DTIC Science & Technology

2015-04-29

during reporting period: Changes in research objectives (if any): Change in AFOSR Program Manager, if any: Extensions granted or milestones slipped , if...SUBTITLE TOWARDS COMBINED ACTIVE CONTROL OF FILM COOLING AND TURBINE BLADE AERODYNAMICS 5a. CONTRACT NUMBER FA9550-08-1-0440 5b. GRANT NUMBER N/A 5c...release. Project Title: Towards Combined Active Control of Film Cooling and Turbine Blade Aerodynamics. Award Number: FA9550-08-1-0440 Dates Covered

The Iraq Community Action Program: USAID’s Agreement with CHF Met Goals, but Greater Oversight Is Needed

DTIC Science & Technology

2011-04-28

communities are unable to contribute materials and services useful to technical infrastructure projects. CHF also reported that 867,070 Iraqis directly...may be in-kind, rather than cash, and can include donated materials and supplies, equipment and services, land and property, and volunteer time and...electrical materials N/A N/Ab 75,000 11 – Provide a water pump and transformer 143,145 3,550 68,740 Total $383,835 $934,744 $1,014,041 Notes: a

Employee Warriors and the Future of the American Fighting Force

DTIC Science & Technology

2002-06-01

Employee Warriors and the Future of the American Fighting Force HUGH S. VEST Major, USAF Fairchild Paper Air University Press Maxwell Air Force...control number. 1. REPORT DATE 00 JUN 2002 2. REPORT TYPE N/A 3. DATES COVERED - 4. TITLE AND SUBTITLE Employee Warriors and the Future of the...American Fighting Force 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK

Coast Guard: Progress Being Made on Deepwater Project, but Risks Remain

DTIC Science & Technology

2001-05-01

Risks Remain GAO-01-564 Form SF298 Citation Data Report Date ("DD MON YYYY") 00MAY2001 Report Type N/A Dates Covered (from... to) ("DD MON YYYY...34) Title and Subtitle COAST GUARD: Progress Being Made on Deepwater Project, but Risks Remain Contract or Grant Number Program Element Number Authors...for this project. As agreed with your office, this report focuses on the major risks facing the Subject Terms Document Classification unclassified

Dragon Drone UAV System

DTIC Science & Technology

2003-09-02

TYPE N/A 3. DATES COVERED - 4. TITLE AND SUBTITLE Dragon Drone UAV System 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER...ABSTRACT unclassified c. THIS PAGE unclassified Standard Form 298 (Rev. 8-98) Prescribed by ANSI Std Z39-18 A E R O S Y S T E M S BAI’s Dragon Drone ...the hundreds. BAI’s Dragon Drone system is the result of combining new ideas and emerging technologies with the in-depth knowl- edge gained from real

Study of Pure Proteins, Nucleic Acids and Their Complexes from Halobacteria of the Dead Sea: RNA Polymerase-DNA Interaction.

DTIC Science & Technology

1987-09-21

objectives of our program are to isolate and characterize a fully active DNA dependent RNA polymerase from the extremely halophilic archaebacteria of the genus...operons in II. Marismortui. The halobacteriaceae are extreme halophiles . They require 3.5 M NaCI for optimal growth an(l no growth is observed below 2...was difficutlt to perform due to the extreme genetic instability in this strain (6). In contrast, the genoine of the extreme halophilic and prototrophic

Adaptive Incentive Controls for Stackelberg Games with Unknown Cost Functionals.

DTIC Science & Technology

1984-01-01

APR EZT:: F I AN 73S e OsL:-: UNCLASSI?:-- Q4~.’~- .A.., 6, *~*i i~~*~~*.- U ADAPTIVE INCENTIVE CONTROLS FOR STACKELBERG GAMES WITH UNKNOWN COST...AD-A161 885 ADAPTIVE INCENTIVE CONTROLS FOR STACKELBERG GAMES WITH i/1 UNKNOWN COST FUNCTIONALSCU) ILLINOIS UNIV AT URBANA DECISION AND CONTROL LAB T...ORGANIZATION 6b. OFFICE SYMBOL 7.. NAME OF MONITORING ORGANIZATION CoriaeLcenef~pda~ Joint Services Electronics Program Laboratory, Univ. of Illinois N/A

Generation of High Purity Photon-Pair in a Short Highly Non-Linear Fiber

DTIC Science & Technology

2013-01-01

Avalanche photodiode. A 10 m long HNLF fabricated by Sumitomo with a core diameter of 4 microns is fusion spliced to a single mode fiber for a...parametric down conversion (SPDC) was first observed in χ(2) nonlinear crystal [3]. However, the compatibility of a nonlinear crystal source with fiber and...PAIR IN A SHORT HIGHLY NON-LINEAR FIBER 5a. CONTRACT NUMBER 5b. GRANT NUMBER FA8750-12-1-0136 5c. PROGRAM ELEMENT NUMBER N/A 6. AUTHOR(S

Radiative Augmented Combustion

DTIC Science & Technology

1988-03-01

PbLFICE SY 7a NAME OF MONITORING ORGANIZATION M.L. ENERGIA , Inc. AFOSR/NA 6r. ADDRESS (City. State. anW ZIP Code) 7b. ADDRESS (City State, and ZIPCode...27 -00 N ’fPECTED 0 6I FOREWORD This is the Final Report on research on Radiative Augmented Combustion conducted at M. L. ENERGIA , Inc. It was a...the first two annual reports prior to this one. The entire research program was performed at ENERGIA , Inc., Princeton, New Jersey, with Dr. Moshe Lavid

Testing and Validation of High Density Resequencing Microarray for Broad Range Biothreat Agents Detection

DTIC Science & Technology

2009-08-11

Competing Interests: One of the contributing authors : Clark Tibbetts, is the Executive Vice President and Chief Technology Officer of Tessarae, LLC...Detection 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR (S) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7...N/A 1021 ng No detection Sin nombre Bunyaviridae III 1021 ng Pulmonary syndrome hantavirus strain Convict Creek 107 1CCHFV = Crimean-Congo hemorrhagic

UI Review Results and NARAC Response

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fisher, J.; Eme, B.; Kim, S.

2017-03-08

This report describes the results of an inter-program design review completed February 16th, 2017, during the second year of a FY16-FY18 NA-84 Technology Integration (TI) project to modernize the core software system used in DOE/NNSA's National Atmospheric Release Advisory Center (NARAC, narac.llnl.gov). This review focused on the graphical user interfaces (GUI) frameworks. Reviewers (described in Appendix 2) were selected from multiple areas of the LLNL Computation directorate, based on their expertise in GUI and Web technologies.

Sustainability Product Properties in Building Information Models

DTIC Science & Technology

2012-09-01

Covrlhovses, Oota c enters, Hospitals IAcvle care and Children’s), Hotels/ Mote ~, Hovses of Worship, K- 12 Schools, Med1cal Offic&s, Offices, Restdence Holts...RenewableContent n/a n/a 70 RenewableMaterial n/a n/a Cotton BiobasedContent n/a n/a 70 BiobasedMaterial n/a n/a Cotton RawMaterialLocation n/a n/a

DOE Office of Scientific and Technical Information (OSTI.GOV)

Parrado, G., E-mail: gparrado@sgc.gov.co; Cañón, Y.; Peña, M., E-mail: mlpena@sgc.gov.co

The Neutron Activation Analysis (NAA) laboratory at the Colombian Geological Survey has developed a technique for multi-elemental analysis of soil and plant matrices, based on Instrumental Neutron Activation Analysis (INAA) using the comparator method. In order to evaluate the analytical capabilities of the technique, the laboratory has been participating in inter-comparison tests organized by Wepal (Wageningen Evaluating Programs for Analytical Laboratories). In this work, the experimental procedure and results for the multi-elemental analysis of four soil and four plant samples during participation in the first round on 2015 of Wepal proficiency test are presented. Only elements with radioactive isotopes withmore » medium and long half-lives have been evaluated, 15 elements for soils (As, Ce, Co, Cr, Cs, Fe, K, La, Na, Rb, Sb, Sc, Th, U and Zn) and 7 elements for plants (Br, Co, Cr, Fe, K, Na and Zn). The performance assessment by Wepal based on Z-score distributions showed that most results obtained |Z-scores| ≤ 3.« less

Effects of pH and anions on the sorption of selenium ions onto magnetite.

PubMed

Kim, Seung Soo; Min, Je Ho; Lee, Jae Kwang; Baik, Min Hoon; Choi, Jong-Won; Shin, Hyung Seon

2012-02-01

This study analyzes the influence of carbonate and silicate, which are generally abundant in granitic groundwater, on the sorption of selenium ions onto magnetite in order to understand the behaviors of selenium in a radioactive waste repository. Selenite was sorbed onto magnetite very well below pH 10, but silicate and carbonate hindered the sorption of selenite onto magnetite. On the other hand, little selenate was sorbed onto magnetite in neutral and weak alkaline solutions of 0.02 M NaNO(3) or NaClO(4), matching the ionic strength in a granitic groundwater, even though silicate or carbonate was not contained in the solutions. The surface complexation constants between selenite and magnetite were obtained by using a geochemical program, FITEQL 4.0, from the experimental data, and the formation of an inner-sphere surface complex such as =FeOSeO(2)(-) was suggested for the sorption of selenite onto magnetite from the diffuse double layer model calculation. Copyright © 2011 Elsevier Ltd. All rights reserved.

Quantum-chemical modeling of smectite clays

NASA Technical Reports Server (NTRS)

Aronowitz, S.; Coyne, L.; Lawless, J.; Rishpon, J.

1982-01-01

A self-consistent charge extended Hueckel program is used in modeling isomorphic substitution of Al(3+) by Na(+), K(+), Mg(2+), Fe(2+), and Fe(3+) in the octahedral layer of a dioctahedral smectite clay, such as montmorillonite. Upon comparison of the energies involved in the isomorphic substitution, it is found that the order for successful substitution is as follows: Al(3+), Fe(3+), Mg(2+), Fe(2+), Na(+), which is equivalent to Ca(2+), and then K(+). This ordering is found to be consistent with experimental observation. The calculations also make it possible to determine the possible penetration of metal ions into the clay's 2:1 crystalline layer. For the cases studied, this type of penetration can occur at elevated temperatures into regions where isomorphic substitution has occurred with metal ions that bear a formal charge of less than 3+. The computed behavior of the electronic structure in the presence of isomorphic substitution is found to be similar to behavior associated with semiconductors.

Summary Report of Summer 2009 NGSI Human Capital Development Efforts at Lawrence Livermore National Laboratory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dougan, A; Dreicer, M; Essner, J

2009-11-16

In 2009, Lawrence Livermore National Laboratory (LLNL) engaged in several activities to support NA-24's Next Generation Safeguards Initiative (NGSI). This report outlines LLNL's efforts to support Human Capital Development (HCD), one of five key components of NGSI managed by Dunbar Lockwood in the Office of International Regimes and Agreements (NA-243). There were five main LLNL summer safeguards HCD efforts sponsored by NGSI: (1) A joint Monterey Institute of International Studies/Center for Nonproliferation Studies-LLNL International Safeguards Policy and Information Analysis Course; (2) A Summer Safeguards Policy Internship Program at LLNL; (3) A Training in Environmental Sample Analysis for IAEA Safeguards Internship;more » (4) Safeguards Technology Internships; and (5) A joint LLNL-INL Summer Safeguards Lecture Series. In this report, we provide an overview of these five initiatives, an analysis of lessons learned, an update on the NGSI FY09 post-doc, and an update on students who participated in previous NGSI-sponsored LLNL safeguards HCD efforts.« less

Improvement of analytical capabilities of neutron activation analysis laboratory at the Colombian Geological Survey

NASA Astrophysics Data System (ADS)

Parrado, G.; Cañón, Y.; Peña, M.; Sierra, O.; Porras, A.; Alonso, D.; Herrera, D. C.; Orozco, J.

2016-07-01

The Neutron Activation Analysis (NAA) laboratory at the Colombian Geological Survey has developed a technique for multi-elemental analysis of soil and plant matrices, based on Instrumental Neutron Activation Analysis (INAA) using the comparator method. In order to evaluate the analytical capabilities of the technique, the laboratory has been participating in inter-comparison tests organized by Wepal (Wageningen Evaluating Programs for Analytical Laboratories). In this work, the experimental procedure and results for the multi-elemental analysis of four soil and four plant samples during participation in the first round on 2015 of Wepal proficiency test are presented. Only elements with radioactive isotopes with medium and long half-lives have been evaluated, 15 elements for soils (As, Ce, Co, Cr, Cs, Fe, K, La, Na, Rb, Sb, Sc, Th, U and Zn) and 7 elements for plants (Br, Co, Cr, Fe, K, Na and Zn). The performance assessment by Wepal based on Z-score distributions showed that most results obtained |Z-scores| ≤ 3.

Real-space imaging of interfacial water with submolecular resolution

NASA Astrophysics Data System (ADS)

Jiang, Ying; Peking University Team

2014-03-01

Water/solid interfaces are vital to our daily lives and also a central theme across an incredibly wide range of scientific disciplines. Resolving the internal structure, i.e. the O-H directionality, of water molecules adsorbed on solid surfaces has been one of the key issues of water science yet remains challenging. Using a low-temperature scanning tunneling microscope (STM), we report the submolecular-resolution imaging of individual water monomers and tetramers on NaCl(001) films supported by a Au(111) substrate at 5 K. The frontier molecular orbitals of adsorbed water were directly visualized, which allowed discriminating the orientation of the monomers and the H-bond directionality of the tetramers in real space. Comparison with ab initio density functional theory calculations reveals that the ability to access the orbital structures of water stems from the electronic decoupling effect provided by the NaCl films and the precisely tunable tip-water coupling. Supported by National Basic Research Programs of China and National Science Foundation of China.

Study of Cetane Properties of ATJ Blends Based on World Survey of Jet Fuels

DTIC Science & Technology

2016-01-28

49.84 N/A N/A N/A 46.92 N/A N/A N/A 12 (100% Syn.) 1 57.79 N/A N/A N/A 53.48 N/A N/A N/A a - Conventional petroleum based jet fuel; b - Oil Shale ...Australia (% Nitrogen content unknown) c - Oil Shale , Australia (Low Nitrogen); d - Oil Shale , Australia (High Nitrogen) U/A – Unavailable in PQIS...fuel b - Oil Shale , Australia (% Nitrogen content unknown) c - Oil Shale , Australia (Low Nitrogen) d - Oil Shale , Australia (High Nitrogen) U/A

Affinity of antigen encounter and other early B-cell signals determine B-cell fate

PubMed Central

Benson, Micah J; Erickson, Loren D; Gleeson, Michael W; Noelle, Randolph J

2010-01-01

Three possible effector fates await the naïve follicular B cell following antigen stimulation in thymus-dependent reactions. Short-lived plasma cells produce an initial burst of germline-encoded protective antibodies, and long-lived plasma cells and memory B cells arise from the germinal center and function to enhance and sustain the humoral immune response. The inherent B-cell receptor affinity of naïve follicular B cells and the contribution of other early B-cell signals pre-determines the pattern of transcription factor expression and the differentiation path taken by these cells. High initial B-cell receptor affinity shunts naïve follicular B-cell clones towards the short-lived plasma cell fate, whereas modest-affinity clones are skewed towards a plasma cell fate and low-affinity clones are recruited into the germinal center and are selected for both long-lived plasma cells and memory B cell pathways. In the germinal center reaction, increased levels of the transcription factor interferon regulatory factor-4 drive the molecular program that dictates differentiation into the long-lived plasma cell phenotype but has no impact on the memory B cell compartment. We hypothesize that graded interferon regulatory factor-4 levels driven by signals to B cells, including B-cell receptor signal strength, are responsible for this branch point in the B-cell terminal differentiation pathway. PMID:17433651

Experimental studies of the NaK 1 3Δ state

NASA Astrophysics Data System (ADS)

Huennekens, J.; Prodan, I.; Marks, A.; Sibbach, L.; Galle, E.; Morgus, T.; Li, Li

2000-11-01

The NaK 1 3Δ state has been studied by the perturbation-facilitated optical-optical double resonance technique. Mixed singlet-triplet levels, A(2)1Σ+(vA,J)˜b(1)3Π(vb,J), were pumped from thermally populated rovibrational levels of the ground state, X(1)1Σ+(vX,J±1), using a single-mode cw dye laser. A single-mode cw Ti:Sapphire laser was then used to further excite the NaK molecules to various 1 3Δ(vΔ,NΔ,JΔ) rovibrational levels which were detected by observing collision-induced 3Λ→a(1)3Σ+ fluorescence in the green part of the spectrum. The measured energies of the 1 3Δ(vΔ,NΔ) levels were fit to a Dunham expansion, and the Dunham coefficients were used to construct the RKR potential curve. Absolute numbering of the 1 3Δ state vibrational levels was established by a comparison of experimental and calculated 1 3Δ(vΔ,NΔ,JΔ)←b(1)3Π(vb,Jb) absorption line strengths. A deperturbation program was used to determine the vibration-dependent 1 3Δ state spin-orbit interaction parameter. Hyperfine structure of the 1 3Δ state was studied, and the Fermi-contact interaction term for this state was determined to be ˜0.0111 cm-1.

Formation of Si grains from a NaSi melt prepared by reaction of SiO2 and Na

NASA Astrophysics Data System (ADS)

Yamane, Hisanori; Morito, Haruhiko; Uchikoshi, Masahito

2013-08-01

A mixture of Na2SiO3 and NaSi was found to be formed by reaction of SiO2 and Na at 650 °C as follows: 5Na+3SiO2→2Na2SiO3+NaSi. Single crystals of NaSi were grown by cooling the mixture of Na2SiO3 and NaSi with an excess amount of Na from 850 °C, and polycrystalline Si was obtained by vaporization of Na from the crystals. Coarse grains of Si were also crystallized by Na evaporation after the formation of Na2SiO3 and Si-dissolved liquid Na at 830 °C. The Si grains were collected by washing the product with water. The yield of the Si grains was 85% of the ideal amount expected from the reaction.

Condition of Si crystal formation by vaporizing Na from NaSi

NASA Astrophysics Data System (ADS)

Morito, Haruhiko; Karahashi, Taiki; Yamane, Hisanori

2012-09-01

NaSi was heated at various Na vapor pressures (pNa 0.1-1.2 atm) and temperatures (973-1173 K) to investigate the condition of Si crystal formation from NaSi by Na evaporation. Silicon single crystals 1-3 mm in diameter were grown by evaporation of Na from Na-Si melt at 1173 K and pNa=0.74 atm.

Using misconceptions research in the design of optics instructional materials and teacher professional development programs

NASA Astrophysics Data System (ADS)

Pompea, Stephen M.; Dokter, Erin F.; Walker, Constance E.; Sparks, Robert T.

2007-06-01

To create the Hands-On Optics program and its associated instructional materials, we needed to understand a number of basic optics misconceptions held by children (and adults) and how to address them through a proper educational approach. The activities have been built with an understanding of the naïve concepts many people have about light, color, and optical phenomena in general. Our own experience is that the concepts that children and adults have of light are often not that different from each other. This paper explores the most common misconceptions about light and color, according to educational research, and describes how they can be addressed in optics education programs. This understanding of misconceptions was useful as well in the professional development component of the program where educators were trained on the Hands-On Optics modules. The professional development work for the optics industry volunteers who worked with the educators was also based on research on how an optics professional can work more effectively in multi-cultural settings-an area with great applicability to industry volunteers working in the very different culture of science centers or after-school programs.

NMR studies on Na+ transport in Synechococcus PCC 6311

NASA Technical Reports Server (NTRS)

Nitschmann, W. H.; Packer, L.

1992-01-01

The freshwater cyanobacterium Synechococcus PCC 6311 is able to adapt to grow after sudden exposure to salt (NaCl) stress. We have investigated the mechanism of Na+ transport in these cells during adaptation to high salinity. Na+ influx under dark aerobic conditions occurred independently of delta pH or delta psi across the cytoplasmic membrane, ATPase activity, and respiratory electron transport. These findings are consistent with the existence of Na+/monovalent anion cotransport or simultaneous Na+/H+ +anion/OH- exchange. Na+ influx was dependent on Cl-, Br-, NO3-, or NO2-. No Na+ uptake occurred after addition of NaI, NaHCO3, or Na2SO4. Na+ extrusion was absolutely dependent on delta pH and on an ATPase activity and/or on respiratory electron transport. This indicates that Na+ extrusion via Na+/H+ exchange is driven by primary H+ pumps in the cytoplasmic membrane. Cells grown for 4 days in 0.5 m NaCl medium, "salt-grown cells," differ from control cells by a lower maximum velocity of Na+ influx and by lower steady-state ratios of [Na+]in/[Na+]out. These results indicate that cells grown in high-salt medium increase their capacity to extrude Na+. During salt adaptation Na+ extrusion driven by respiratory electron transport increased from about 15 to 50%.

An experimental study of nettle feeding in captive gorillas.

PubMed

Tennie, Claudio; Hedwig, Daniela; Call, Josep; Tomasello, Michael

2008-06-01

Mountain gorillas (Gorilla beringei beringei) in Karisoke, Rwanda, feed on the stinging nettle Laportea alatipes by means of elaborate processing skills. Byrne [e.g. Philosophical Transactions of the Royal Society of London, Series B, Biological Sciences 358:529-536, 2003] has claimed that individuals acquire these skills by means of the so-called program-level imitation, in which the overall sequence of problem-solving steps (not the precise actions) is reproduced. In this study we present western lowland gorillas (Gorilla gorilla gorilla) with highly similar nettles. Twelve gorillas in three different groups (including also one nettle-naïve gorilla) used the same program-level technique as wild mountain gorillas (with differences mainly on the action level). Chimpanzees, orangutans, and bonobos did not show these program-level patterns, nor did the gorillas when presented with a plant similar in structural design but lacking stinging defenses. We conclude that although certain aspects (i.e. single actions) of this complex skill may be owing to social learning, at the program level gorilla nettle feeding derives mostly from genetic predispositions and individual learning of plant affordances. Copyright 2008 Wiley-Liss, Inc.

Equilibrium Speciation of Select Lanthanides in the Presence of Acidic Ligands in Homo- and Heterogeneous Solutions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Robinson, Troy A

2011-08-01

This dissertation explores lanthanide speciation in liquid solution systems related to separation schemes involving the acidic ligands: bis(2-ethylhexyl) phosphoric acid (HDEHP), lactate, and 8-hydroxyquinoline. Equilibrium speciation of neodymium (Nd 3+), sodium (Na+), HDEHP, water, and lactate in the TALSPEAK liquid-liquid extraction system was explored under varied Nd 3+ loading of HDEHP in the organic phase and through extraction from aqueous HCl and lactate media. System speciation was probed through vapor pressure osmometry, visible and Fourier Transform Infrared (FTIR) spectroscopy, 22Na and 13C labeled lactate radiotracer distribution measurements, Karl Fischer titrations, and equilibrium pH measurements. Distribution of Nd 3+, Na +,more » lactate, and equilibrium pH were modeled using the SXLSQI software to obtain logKNd and logKNa extraction constants under selected conditions. Results showed that high Nd 3+ loading of the HDEHP led to Nd 3+ speciation that departs from the ion exchange mechanism and includes formation of highly aggregated, polynuclear [NdLactate(DEHP) 2] x; (with x > 1). By substituting lanthanum (La 3+) for Nd 3+ in this system, NMR scoping experiments using 23Na, 31P nuclei and 13C labeled lactate were performed. Results indicated that this technique is sensitive to changes in system speciation, and that further experiments are warranted. In a homogeneous system representing the TALSPEAK aqueous phase, Lactate protonation behavior at various temperatures was characterized using a combination of potentiometric titration and modeling with the Hyperquad computer program. The temperature dependent deprotonation behavior of lactate showed little change with temperature at 2.0 M NaCl ionic strength. Cloud point extraction is a non-traditional separation technique that starts with a homogeneous phase that becomes heterogeneous by the micellization of surfactants through the increase of temperature. To better understand the behavior of europium (Eu 3+) and 8-hydroxyquinoline under cloud point extraction conditions, potentiometric and spectrophotometric titrations coupled with modeling with Hyperquad and SQUAD computer programs were performed to assess europium (Eu 3+) and 8-hydroxyquinoline speciation. Experiments in both water and a 1wt% Triton X-114/water mixed solvent were compared to understand the effect of Triton X-114 on the system speciation. Results indicated that increased solvation of 8-hydroxyquinoline by the mixed solvent lead to more stable complexes involving 8-hydroxyquinoline than in water, whereas competition between hydroxide and Triton X-114 for Eu 3+ led to lower stability hydrolysis complexes in the mixed solvent than in water. Lanthanide speciation is challenging due to the trivalent oxidation state that leads to multiple ligand complexes, including some mixed complexes. The complexity of the system demands well-designed and precise experiments that capture the nuances of the chemistry. This work increased the understanding of lanthanide speciation in the explored systems, but more work is required to produce a comprehensive understanding of the speciation involved.« less

Na/K pump inactivation, subsarcolemmal Na measurements, and cytoplasmic ion turnover kinetics contradict restricted Na spaces in murine cardiac myocytes

PubMed Central

Lu, Fang-Min

2017-01-01

Decades ago, it was proposed that Na transport in cardiac myocytes is modulated by large changes in cytoplasmic Na concentration within restricted subsarcolemmal spaces. Here, we probe this hypothesis for Na/K pumps by generating constitutive transsarcolemmal Na flux with the Na channel opener veratridine in whole-cell patch-clamp recordings. Using 25 mM Na in the patch pipette, pump currents decay strongly during continuous activation by extracellular K (τ, ∼2 s). In contradiction to depletion hypotheses, the decay becomes stronger when pump currents are decreased by hyperpolarization. Na channel currents are nearly unchanged by pump activity in these conditions, and conversely, continuous Na currents up to 0.5 nA in magnitude have negligible effects on pump currents. These outcomes are even more pronounced using 50 mM Li as a cytoplasmic Na congener. Thus, the Na/K pump current decay reflects mostly an inactivation mechanism that immobilizes Na/K pump charge movements, not cytoplasmic Na depletion. When channel currents are increased beyond 1 nA, models with unrestricted subsarcolemmal diffusion accurately predict current decay (τ ∼15 s) and reversal potential shifts observed for Na, Li, and K currents through Na channels opened by veratridine, as well as for Na, K, Cs, Li, and Cl currents recorded in nystatin-permeabilized myocytes. Ion concentrations in the pipette tip (i.e., access conductance) track without appreciable delay the current changes caused by sarcolemmal ion flux. Importantly, cytoplasmic mixing volumes, calculated from current decay kinetics, increase and decrease as expected with osmolarity changes (τ >30 s). Na/K pump current run-down over 20 min reflects a failure of pumps to recover from inactivation. Simulations reveal that pump inactivation coupled with Na-activated recovery enhances the rapidity and effectivity of Na homeostasis in cardiac myocytes. In conclusion, an autoregulatory mechanism enhances cardiac Na/K pump activity when cytoplasmic Na rises and suppresses pump activity when cytoplasmic Na declines. PMID:28606910

Concentration dependence of Li+/Na+ diffusion in manganese hexacyanoferrates

NASA Astrophysics Data System (ADS)

Takachi, Masamitsu; Fukuzumi, Yuya; Moritomo, Yutaka

2016-06-01

Manganese hexacyanoferrates (Mn-HCFs) with a jungle-gym-type structure are promising cathode materials for Li+/Na+ secondary batteries (LIBs/SIBs). Here, we investigated the diffusion constants D Li/D Na of Li+/Na+ against the Li+/Na+ concentration x Na/x Li and temperature (T) of A 1.32Mn[Fe(CN)6]0.833.6H2O (A = Li and Na). We evaluated the activation energy E\\text{a}\\text{Li}/E\\text{a}\\text{Na} of D Li/D Na against x Na/x Li. We found that E\\text{a}\\text{Na} steeply increases with x Na from 0.41 eV at x Na = 0.69 to 0.7 eV at 1.1. The increase in E\\text{a}\\text{Na} is ascribed to the occupancy effect of the Na+ site. The increase in E\\text{a}\\text{Li} is suppressed, probably because the number of Li+ sites is three times that of Na+ sites.

Metal Residue Deposition from Military Pyrotechnic Devices and Field Sampling Guidance

DTIC Science & Technology

2012-05-01

given NA 0.002 NA NA Chromium Oxide 1308-38-9 NA NA NA 0.015 Cobalt Naphthenate 61789-51-3 NA NA NA 0.017 Copper Oxide Black 1317-38-0 NA 1.32 NA...the whistling booby trap simulators included 73% potassium perchlorate, 24% gallic acid , and 3 % red gum (McIntyre 1980). Whereas the booby-trap...M21 Flash Artillery Simulator 50 3785.8 2/5/10 All – indicates the entire volume of stained snow was removed . MI – multi-increment. Rep

Electronic structure, Dirac points and Fermi arc surface states in three-dimensional Dirac semimetal Na3Bi from angle-resolved photoemission spectroscopy

NASA Astrophysics Data System (ADS)

Aiji, Liang; Chaoyu, Chen; Zhijun, Wang; Youguo, Shi; Ya, Feng; Hemian, Yi; Zhuojin, Xie; Shaolong, He; Junfeng, He; Yingying, Peng; Yan, Liu; Defa, Liu; Cheng, Hu; Lin, Zhao; Guodong, Liu; Xiaoli, Dong; Jun, Zhang; M, Nakatake; H, Iwasawa; K, Shimada; M, Arita; H, Namatame; M, Taniguchi; Zuyan, Xu; Chuangtian, Chen; Hongming, Weng; Xi, Dai; Zhong, Fang; Xing-Jiang, Zhou

2016-07-01

The three-dimensional (3D) Dirac semimetals have linearly dispersive 3D Dirac nodes where the conduction band and valence band are connected. They have isolated 3D Dirac nodes in the whole Brillouin zone and can be viewed as a 3D counterpart of graphene. Recent theoretical calculations and experimental results indicate that the 3D Dirac semimetal state can be realized in a simple stoichiometric compound A 3Bi (A = Na, K, Rb). Here we report comprehensive high-resolution angle-resolved photoemission (ARPES) measurements on the two cleaved surfaces, (001) and (100), of Na3Bi. On the (001) surface, by comparison with theoretical calculations, we provide a proper assignment of the observed bands, and in particular, pinpoint the band that is responsible for the formation of the three-dimensional Dirac cones. We observe clear evidence of 3D Dirac cones in the three-dimensional momentum space by directly measuring on the k x -k y plane and by varying the photon energy to get access to different out-of-plane k z s. In addition, we reveal new features around the Brillouin zone corners that may be related with surface reconstruction. On the (100) surface, our ARPES measurements over a large momentum space raise an issue on the selection of the basic Brillouin zone in the (100) plane. We directly observe two isolated 3D Dirac nodes on the (100) surface. We observe the signature of the Fermi-arc surface states connecting the two 3D Dirac nodes that extend to a binding energy of ˜150 meV before merging into the bulk band. Our observations constitute strong evidence on the existence of the Dirac semimetal state in Na3Bi that are consistent with previous theoretical and experimental work. In addition, our results provide new information to clarify on the nature of the band that forms the 3D Dirac cones, on the possible formation of surface reconstruction of the (001) surface, and on the issue of basic Brillouin zone selection for the (100) surface. Project supported by the National Natural Science Foundation of China (Grant No. 11574367), the National Basic Research Program of China (Grant Nos. 2013CB921700, 2013CB921904, and 2015CB921300), and the Strategic Priority Research Program (B) of the Chinese Academy of Sciences (Grant No. XDB07020300). The synchrotron radiation experiments have been done under the HiSOR Proposal numbers, 12-B-47 and 13-B-16.

Response of saliva Na/K ratio to changing Na supply of lactating cows under tropical conditions.

PubMed

Thiangtum, Wandee; Schonewille, J Thomas; Verstegen, Martin Wa; Arsawakulsudhi, Supot; Rukkwamsuk, Theera; Hendriks, Wouter H

2017-06-01

Factorial determination of the sodium (Na) requirement of heat-stressed lactating cows is hindered by accurate estimates of the Na losses through sweat. Direct studies, therefore, may be needed requiring information on the time course of healthy animals to become Na depleted and the subsequent rate of repletion. The rate of Na depletion and subsequent rate of Na repletion with two levels of dietary Na to lactating dairy cows housed under tropical conditions were investigated using the salivary Na/K. The 12 lactating cows (salivary Na/K ratio 14.6) rapidly developed clinical signs of Na deficiency, including pica, polyuria and polydipsia, reduced body weight and reduced milk yield when fed a low-Na ration (0.33 g kg -1 dry matter (DM)) for 3 weeks. Deficiency symptoms were associated with a rapid decrease in salivary Na/K ratio to <4.3 from 7 to 21 days. Subsequent repletion of the cows with NaCl to a ration concentration of 1.1 or 1.6 g Na kg -1 DM for 5 weeks did not restore salivary Na/K ratio to values of >6. A daily Na intake of heat-stressed lactating cows to a ration intake of 1.6 g Na kg -1 DM was insufficient to restore Na deficiency. One week was sufficient to deplete heat-stressed lactating cows of Na, allowing for rapid dose-response studies utilizing the salivary Na/K ratio as a parameter for Na status of cows under tropical conditions. © 2016 Society of Chemical Industry. © 2016 Society of Chemical Industry.

[Effects of different salt and alkali stresses on ion distribution in Red globe/Beta grapevines].

PubMed

Du, Yuan-peng; Jin, Xue-juan; Guo, Shu-hua; Fu, Qing-qing; Zhai, Heng

2015-06-01

The potted Red globe/Beta grapevines were selected to irrigated with NaCl, Na2SO4, NaHCO3, NH4Cl, (NH4)2SO4. Hence, the ions which induced leaf etiolation were screened and the impacts of different salt and alkali on ion distribution in different organs of grapevines were investigated. It was found that NaHCO3 exerted the greatest effects on grapevines, leaf etiolation at 14 days after treatment. By contrast, NaCl and NH4Cl treatments induced leaf etiolation at 28 days after treatment. The Na+ content in all the detected organs were significantly increased under NaHCO3 and NaCl treatment, and Na+ content in root under NaHCO3 treatment was 6.4 times as that in control root. NaHCO3 and NaCl treatments significantly decreased K+ content in the organs with the exception of leaf. NaHCO3 treatment significantly decreased K/Na in different organs, which declined to 0.1 in root. By contrast, NaCl treatment significantly decreased K/Na in the detected organs with exception of stem. Besides, the transport of Ca2+, Mg2+, Fe2+ to aboveground organs was significantly decreased by NaHCO3 and NaCl treatments. K/Na ratio in the detected organs were decreased under NH4Cl, (NH4) 2SO4 and Na2SO4 treatments, especially under NH4 Cl treatment. Taken together, NaHCO3 was the primary factor resulting in leaf etiolation, followed by NaCl and NH4Cl, while (NH4) 2SO4 and Na2SO4 produced impacts.

Remediation of problematic residents--A national survey.

PubMed

Bhatti, Nasir I; Ahmed, Aadil; Stewart, Michael G; Miller, Robert H; Choi, Sukgi S

2016-04-01

Despite careful selection processes, residency programs face the challenge of training residents who fall below minimal performance standards. Poor performance of a resident can endanger both patient safety and the reputation of the residency program. It is important, therefore, for a program to identify such residents and implement strategies for their successful remediation. The purpose of our study was to gather information on evaluation and remediation strategies employed by different otolaryngology programs. Cross-sectional survey. We conducted a national survey, sending a questionnaire to the program directors of 106 otolaryngology residency programs. We collected information on demographics of the program, identification of problematic residents, and remediation strategies. The response rate was 74.5%, with a 2% cumulative incidence of problematic residents in otolaryngology programs during the past 10 years. The most frequently reported deficiencies of problematic residents were unprofessional behavior with colleagues/staff (38%), insufficient medical knowledge (37%), and poor clinical judgment (34%). Personal or professional stress was the most frequently identified underlying problem (70.5%). Remediation efforts included general counseling (78%), frequent feedback sessions (73%), assignment of a mentor (58%), and extra didactics (47%). These remediation efforts failed to produce improvement in 23% of the identified residents, ultimately leading to their dismissal. The apparent deficiencies, underlying causes, and remediation strategies vary among otolaryngology residency programs. Based on the results of this survey, we offer recommendations for the early identification of problematic residents and a standardized remediation plan. NA. © 2015 The American Laryngological, Rhinological and Otological Society, Inc.

Key results of battery performance and life tests at Argonne National Laboratory

NASA Astrophysics Data System (ADS)

Deluca, W. H.; Gillie, K. R.; Kulaga, J. E.; Smaga, J. A.; Tummillo, A. F.; Webster, C. E.

1991-12-01

Advanced battery technology evaluations are performed under simulated electric vehicle operating conditions at Argonne National Laboratory's & Diagnostic Laboratory (ADL). The ADL provide a common basis for both performance characterization and life evaluation with unbiased application of tests and analyses. This paper summarizes the performance characterizations and life evaluations conducted in 1991 on twelve single cells and eight 3- to 360-cell modules that encompass six battery technologies (Na/S, Li/MS, Ni/MH, Zn/Br, Ni/Fe, and Pb-Acid). These evaluations were performed for the Department of Energy, Office of Transportation Technologies, Electric and Hybrid Propulsion Division. The results measure progress in battery R & D programs, compare battery technologies, and provide basic data for modeling and continuing R & D to battery users, developers, and program managers.

A central role for Notch in effector CD8+ T cell differentiation

PubMed Central

Backer, Ronald A.; Helbig, Christina; Gentek, Rebecca; Kent, Andrew; Laidlaw, Brian J.; Dominguez, Claudia X.; de Souza, Yevan S.; van Trierum, Stella E.; van Beek, Ruud; Rimmelzwaan, Guus F.; ten Brinke, Anja; Willemsen, A. Marcel; van Kampen, Antoine H. C.; Kaech, Susan M.; Blander, J. Magarian; van Gisbergen, Klaas; Amsen, Derk

2014-01-01

Activated CD8+ T cells choose between terminal effector cell (TEC) or memory precursor cell (MPC) fates. We show that Notch controls this choice. Notch promoted differentiation of immediately protective TECs and was correspondingly required for clearance of an acute influenza virus infection. Notch activated a major portion of the TEC-specific gene expression program and suppressed the MPC-specific program. Expression of Notch receptors was induced on naïve CD8+ T cells by inflammatory mediators and interleukin 2 (IL-2) via mTOR and T-bet dependent pathways. These pathways were subsequently amplified downstream of Notch, creating a positive feedback loop. Notch thus functions as a central hub where information from different sources converges to match effector T cell differentiation to the demands of the infection. PMID:25344724

Teaching Ionic Solvation Structure with a Monte Carlo Liquid Simulation Program

NASA Astrophysics Data System (ADS)

Serrano, Agostinho; Santos, Flávia M. T.; Greca, Ileana M.

2004-09-01

It is shown how basic aspects of ionic solvation structure, a fundamental topic for understanding different concepts and levels of representations of chemical structure and transformation, can be taught with the help of a Monte Carlo simulation package for molecular liquids. By performing a pair distribution function analysis of the solvation of Na + , Cl , and Ar in water, it is shown that it is feasible to explain the differences in solvation for these differently charged solutes. Visual representations of the solvated ions can also be employed to help the teaching activity. This may serve as an introduction to the study of solvation structure in chemistry undergraduate courses. The advantages of using tested, up-to-date scientific simulation programs as the fundamental bricks in the construction of virtual laboratories is also discussed.

Kinetic and mechanistic analysis of dinucleotide and oligonucleotide formation from the 5'-phosphorimidazolide of adenosine on Na(+)-montmorillonite

NASA Technical Reports Server (NTRS)

Kawamura, K.; Ferris, J. P.

1994-01-01

The rate constants for the condensation reaction of the 5'-phosphorimidazolide of adenosine (ImpA) to form dinucleotides and oligonucleotides have been measured in the presence of Na(+)-volclay (a Na(+)-montmorillonite) in pH 8 aqueous solution at 25 degrees C. The rates of the reaction of ImpA with an excess of adenosine 5'-monophosphoramidate (NH2pA), P1,P2-diadenosine 5',5'-pyrophosphate (A5'ppA), or adenosine 5'-monophosphate (5'-AMP or pA) in the presence of the montmorillonite to form NH2pA3'pA, A5'ppA3'pA, and pA3'pA, respectively, were measured. Only 3',5'-linked products were observed. The magnitude of the rate constants decrease in the order NH2pA3'pA > A5'-ppA3'pA > pA3'pA. The binding of ImpA to montmorillonite was measured, and the adsorption isotherm was determined. The binding of ImpA to montmorillonite and the formation of higher oligonucleotides is not observed in the absence of salts. Mg2+ enhances binding and oligonucleotide formation more than Ca2+ and Na+. The rate constants for the oligonucleotide formation were determined from the reaction products formed from 10 to 40 mM ImpA in the presence of Na(+)-montmorillonite using the computer program SIMFIT. The magnitudes of the rate constants for the formation of oligonucleotides increased in the order 2-mer < 3-mer < 4-mer ... 7-mer. The rate constants for dinucleotide and trinucleotide formation are more than 1000 times larger than those measured in the absence of montmorillonite. The rate constants for the formation of dinucleotide, trinucleotide, and tetranucleotide are 41,2.6, and 3.7 times larger than those for the formation of oligo(G)s with a poly(C) template. The hydrolysis of ImpA was accelerated 35 times in the presence of the montmorillonite. The catalytic ability of montmorillonite to form dinucleotides and oligonucleotides is quantitatively evaluated and possible pathways for oligo(A) formation are proposed.

Thermal decomposition of sodium amide, NaNH2, and sodium amide hydroxide composites, NaNH2-NaOH.

PubMed

Jepsen, Lars H; Wang, Peikun; Wu, Guotao; Xiong, Zhitao; Besenbacher, Flemming; Chen, Ping; Jensen, Torben R

2016-09-14

Sodium amide, NaNH 2 , has recently been shown to be a useful catalyst to decompose NH 3 into H 2 and N 2 , however, sodium hydroxide is omnipresent and commercially available NaNH 2 usually contains impurities of NaOH (<2%). The thermal decomposition of NaNH 2 and NaNH 2 -NaOH composites is systematically investigated and discussed. NaNH 2 is partially dissolved in NaOH at T > 100 °C, forming a non-stoichiometric solid solution of Na(OH) 1-x (NH 2 ) x (0 < x < ∼0.30), which crystallizes in an orthorhombic unit cell with the space group P2 1 2 1 2 1 determined by synchrotron powder X-ray diffraction. The composite xNaNH 2 -(1 - x)NaOH (∼0.70 < x < 0.72) shows a lowered melting point, ∼160 °C, compared to 200 and 318 °C for neat NaNH 2 and NaOH, respectively. We report that 0.36 mol of NH 3 per mol of NaNH 2 is released below 400 °C during heating in an argon atmosphere, initiated at its melting point, T = 200 °C, possibly due to the formation of the mixed sodium amide imide solid solution. Furthermore, NaOH reacts with NaNH 2 at elevated temperatures and provides the release of additional NH 3 .

Nonlinear inversion of resistivity sounding data for 1-D earth models using the Neighbourhood Algorithm

NASA Astrophysics Data System (ADS)

Ojo, A. O.; Xie, Jun; Olorunfemi, M. O.

2018-01-01

To reduce ambiguity related to nonlinearities in the resistivity model-data relationships, an efficient direct-search scheme employing the Neighbourhood Algorithm (NA) was implemented to solve the 1-D resistivity problem. In addition to finding a range of best-fit models which are more likely to be global minimums, this method investigates the entire multi-dimensional model space and provides additional information about the posterior model covariance matrix, marginal probability density function and an ensemble of acceptable models. This provides new insights into how well the model parameters are constrained and make assessing trade-offs between them possible, thus avoiding some common interpretation pitfalls. The efficacy of the newly developed program is tested by inverting both synthetic (noisy and noise-free) data and field data from other authors employing different inversion methods so as to provide a good base for comparative performance. In all cases, the inverted model parameters were in good agreement with the true and recovered model parameters from other methods and remarkably correlate with the available borehole litho-log and known geology for the field dataset. The NA method has proven to be useful whilst a good starting model is not available and the reduced number of unknowns in the 1-D resistivity inverse problem makes it an attractive alternative to the linearized methods. Hence, it is concluded that the newly developed program offers an excellent complementary tool for the global inversion of the layered resistivity structure.

Cost-benefit analyses of supplementary measles immunisation in the highly immunized population of New Zealand.

PubMed

Hayman, D T S; Marshall, J C; French, N P; Carpenter, T E; Roberts, M G; Kiedrzynski, T

2017-09-05

As endemic measles is eliminated from countries through increased immunisation, the economic benefits of enhanced immunisation programs may come into question. New Zealand has suffered from outbreaks after measles introductions from abroad and we use it as a model system to understand the benefits of catch up immunisation in highly immunised populations. We provide cost-benefit analyses for measles supplementary immunisation in New Zealand. We model outbreaks based on estimates of the basic reproduction number in the vaccinated population (R v , the number of secondary infections in a partially immunised population), based on the number of immunologically-naïve people at district and national levels, considering both pre- and post-catch up vaccination scenarios. Our analyses suggest that measles R v often includes or exceeds one (0.18-3.92) despite high levels of population immunity. We calculate the cost of the first 187 confirmed and probable measles cases in 2014 to be over NZ$1 million (∼US$864,200) due to earnings lost, case management and hospitalization costs. The benefit-cost ratio analyses suggest additional vaccination beyond routine childhood immunisation is economically efficient. Supplemental vaccination-related costs are required to exceed approximately US$66 to US$1877 per person, depending on different scenarios, before supplemental vaccination is economically inefficient. Thus, our analysis suggests additional immunisation beyond childhood programs to target naïve individuals is economically beneficial even when childhood immunisation rates are high. Copyright © 2017 Elsevier Ltd. All rights reserved.

Problem-based learning in medical informatics for undergraduate medical students: an experiment in two medical schools.

PubMed

Burgun, Anita; Darmoni, Stéfan; Duff, Franck Le; Wéber, Jacques

2006-05-01

The objective of this work was to assess problem-based learning (PBL) as a method for teaching information and communication technology in medical informatics (MI) courses. A study was conducted in the Schools of Medicine of Rennes and Rouen (France) with third-year medical students. The "PBL-in-MI" sessions included a first tutorial group meeting, then personal work, followed by a second tutorial group meeting. A problem that simulated practice and was focused on information technology was discussed. In Rouen, the students were familiar with PBL, and they enrolled on a voluntary basis, while in Rennes, the students were first-ever participants in PBL courses, and the program was mandatory. One hundred and seventy-seven students participated in the PBL-in-MI sessions and were given a questionnaire in order to evaluate qualitatively the sessions. The response rate was 92.1%. The overall opinion of the students was good. 69.8% responded positively to the program. In Rouen, where the students participated in PBL-in-MI sessions on a voluntary basis, the students were significantly more enthusiastic about PBL-in-MI. Moreover, attitudes and opinions of students are plausibly related to differences in previous PBL skills. The fact that the naïve group had two tutors, one trained and one naïve as the students, has been investigated. Teacher naivety was an explanatory factor for the differences between Rennes and Rouen.

Evaluation of extra- and intracellular apparent diffusion coefficient of sodium in rat skeletal muscle: effects of prolonged ischemia.

PubMed

Babsky, Andriy M; Topper, Stephen; Zhang, Hong; Gao, Yong; James, Judy R; Hekmatyar, Shahryar K; Bansal, Navin

2008-03-01

The mechanism of water and sodium apparent diffusion coefficient (ADC) changes in rat skeletal muscle during global ischemia was examined by in vivo 1H and 23Na magnetic resonance spectroscopy (MRS). The ADCs of Na+ and water are expected to have similar characteristics because sodium is present as an aqua-cation in tissue. The shift reagent, TmDOTP5(-), was used to separate intra- and extracellular sodium (Na+i and Na+e, respectively) signals. Water, total tissue sodium (Na+t), Na+i, and Na+e ADCs were measured before and 1, 2, 3, and 4 hr after ischemia. Contrary to the general perception, Na+i and Na+e ADCs were identical before ischemia. Thus, ischemia-induced changes in Na+e ADC cannot be explained by a simple change in the size of relative intracellular or extracellular space. Na+t and Na+e ADCs decreased after 2-4 hr of ischemia, while water and Na+i ADC remained unchanged. The correlation between Na+t and Na+e ADCs was observed because of high Na+e concentration. Similarly, the correlation between water and Na+i ADCs was observed because cells occupy 80% of the tissue space in the skeletal muscle. Ischemia also caused an increase in the Na+i and an equal decrease in Na+e signal intensity due to cessation of Na+/K+-ATPase function. (c) 2008 Wiley-Liss, Inc.

Effects of high dietary sodium chloride content on performance and sodium and potassium balance in growing pigs.

PubMed

Chittavong, Malavanh; Jansson, Anna; Lindberg, Jan Erik

2013-10-01

Thirty castrated male Moo Lath pigs (6-8 weeks of age) were used in a 15-week growth trial to study the effect of high dietary sodium chloride (NaCl) content on feed and water intake, performance, sodium (Na) and potassium (K) balance, and plasma aldosterone concentration. The pigs were randomly allocated (ten per treatment) to diets containing 0.24 % Na (Na0.24), 0.28 % Na (Na0.28), and 0.32 % Na (Na0.32) per kg diet. Feed and water was provided ad libitum, and water consumption, feed offered, and feed residues were recorded daily. Every third week, the pigs were weighed, blood samples were collected, and a 3-day total collection of urine and feces was performed. Water intake was higher (P = 0.001) in pigs fed with diets Na0.28 (3.7 L/day) and Na0.32 (3.9 L/day) than in pigs fed with diet Na0.24 (3.4 L/day), and dry matter (DM) intake was higher on diet Na0.32 (P = 0.041) than on the other diets. The average daily body weight (BW) gain was higher on diet Na0.32 than on the other diets (P = 0.031). The feed conversion ratio (in kilogram feed DM to kilogram BW gain) was 4.6, 4.6, and 4.1 on treatments Na0.24, Na0.28, and Na0.32, respectively (P = 0.14). The highest Na balance was observed on diet Na0.32 followed by diets Na0.28 and Na0.24 (P < 0.001), while there was no treatment-related pattern for the K balance. The Na/K ratio in feces and urine increased (P < 0.001), and the K/Na ratio in feces (P < 0.001) decreased with increasing Na content in the diet. Plasma aldosterone concentration decreased (P < 0.001) with increasing dietary content of Na. These results indicate that high NaCl intake and free access to water will increase Na balance but do not negatively influence feed intake and performance of growing local pigs.

Metal Residue Deposition from Military Pyrotechnic Devices and Field Sampling Guidance

DTIC Science & Technology

2012-05-01

0.002 26.4 NA 0.082 Cerium none given NA 0.002 NA NA Chromium Oxide 1308-38-9 NA NA NA 0.015 Cobalt Naphthenate 61789-51-3 NA NA NA 0.017 Copper...the 1980s, the constituents in the whistling booby trap simulators included 73% potassium perchlorate, 24% gallic acid , and 3 % red gum (McIntyre...Test 3, MI snow sample, Rep 3 M21 Flash Artillery Simulator 50 3785.8 2/5/10 All – indicates the entire volume of stained snow was removed . MI

Study of Np(V) Sorption by Ionic Exchange on Na, K, Ca and Mg-Montmorillonite

NASA Astrophysics Data System (ADS)

Benedicto, A.; Begg, J.; Zhao, P.; Kersting, A. B.; Zavarin, M.

2012-12-01

The transport behavior of actinides in soil and ground water are highly influenced by clay minerals due to their ubiquity in the environment, reactivity and colloidal properties. Neptunium(V) has been introduced in the environment as a result of nuclear weapons testing [e.g. 1, 2] and is a radionuclide of potential interest for safety assessment of high level radioactive waste disposal because its long half-life and high toxicity [3]. Surface complexation and ionic exchange have been identified as Np(V) sorption mechanisms onto montmorillonite. At pH below 5, Np(V) sorption is mainly attributed to ionic exchange. This study examines Np(V) ion exchange on Na, K, Ca and Mg forms of montmorillonite. Experiments were carried out using 237Np concentrations between 2 x 10-8 M and 5 x 10-6 M at three different ionic strengths 0.1, 0.01 and 0.001M. The pH was maintained at 4.5. Np(V) sorption to montmorillonite homoionized with monovalent cations (Na and K) demonstrated a markedly different behavior to that observed for montmorillonite homoionized with divalent cations (Ca and Mg). Np sorption to Na and K-montmorillonite was greater than Np sorption to Ca and Mg-montmorillonite. Isotherms with Na and K-montmorillonite showed a strong dependence on ionic strength: the percentage of Np adsorbed was near zero at 0.1M ionic strength, but increased to 30% at 0.001 M ionic strength. This suggests ionic exchange is the main Np adsorption mechanism under the experimental conditions investigated. Dependence on ionic strength was not observed in the Np sorption isotherms for Ca and Mg-montmorillonite indicating a low exchange capacity between Np and divalent cations. Modeling of the sorption experimental data will allow determination of the Na+↔NpO2+ and K+↔NpO2+ ionic exchange constants on montmorillonite. References: [1] A. R. Felmy; K. J. Cantrell; S. D. Conradson, Phys. Chem. Earth 2010, 35, 292-297 [2] D. K. Smith; D. L. Finnegan; S. M. Bowen, J. Environ. Radioact. 2003, 67, (1), 35-51 [3] N. Kozai; T. Ohnuki; S. Muraoka, J. Nucl. Sci. Technol. 1993, 30, (11), 1153-1159 This work was funded by U. S. DOE Office of Biological & Environmental Sciences, Subsurface Biogeochemistry Research Program, and performed under the auspices of the U. S. Department of Energy by Lawrence Livermore National Security, LLC under Contract DE-AC52-07NA27344. A. Benedicto was supported by a Spanish Ministry of Science and Innovation 'FPI' pre-doctoral contract in CIEMAT (Spain). LLNL-ABS-570160

A liquid-metal filling system for pumped primary loop space reactors

NASA Astrophysics Data System (ADS)

Crandall, D. L.; Reed, W. C.

Some concepts for the SP-100 space nuclear power reactor use liquid metal as the primary coolant in a pumped loop. Prior to filling ground engineering test articles or reactor systems, the liquid metal must be purified and circulated through the reactor primary system to remove contaminants. If not removed, these contaminants enhance corrosion and reduce reliability. A facility was designed and built to support Department of Energy Liquid Metal Fast Breeder Reactor tests conducted at the Idaho National Engineering Laboratory. This test program used liquid sodium to cool nuclear fuel in in-pile experiments; thus, a system was needed to store and purify sodium inventories and fill the experiment assemblies. This same system, with modifications and potential changeover to lithium or sodium-potassium (NaK), can be used in the Space Nuclear Power Reactor Program. This paper addresses the requirements, description, modifications, operation, and appropriateness of using this liquid-metal system to support the SP-100 space reactor program.

Integrating cultural values, beliefs, and customs into pregnancy and postpartum care: lessons learned from a Hawaiian public health nursing project.

PubMed

Mayberry, L J; Affonso, D D; Shibuya, J; Clemmens, D

1999-06-01

Determining the elements of culturally competent health care is an important goal for nurses. This goal is particularly integral in efforts to design better preventive health care strategies for pregnant and postpartum women from multiple cultural and ethnic backgrounds. Learning about the values, beliefs, and customs surrounding health among the targeted groups is essential, but integrating this knowledge into the actual health care services delivery system is more difficult. The success of a prenatal and postpartum program developed for native Hawaiian, Filipino, and Japanese women in Hawaii has been attributed to the attention on training, direct care giving, and program monitoring participation by local cultural and ethnic healers and neighborhood leaders living in the community, with coordination by public health nurses. This article profiles central design elements with examples of specific interventions used in the Malama Na Wahine or Caring for Pregnant Women program to illustrate a unique approach to the delivery of culturally competent care.

Exercise in fibromyalgia and related inflammatory disorders: known effects and unknown chances.

PubMed

Ortega, E; García, J J; Bote, M E; Martín-Cordero, L; Escalante, Y; Saavedra, J M; Northoff, H; Giraldo, E

2009-01-01

Fibromyalgia (FM) is characterised by chronic widespread pain and allodynia (pain from stimuli which are not normally painful with pain that may occur other than in the area stimulated) of more than 3 months duration. The current hypothesis of the aetiology of FM includes inflammatory and neuroendocrine disorders. The biophysiology of this syndrome, however; remains still widely elusive, and there are no formally approved therapies. Non-pharmacological interventions in FM patients include habitual exercise programs which improve physical function and quality of life of patients and may even reduce pain. However the mechanisms through which exercise benefits FM symptoms needs to be elucidated. In this article we firstly review the main topics and characteristics of the FM syndrome, while focusing our attention on the inflammatory hypothesis of FM, as well as on the beneficial effects of habitual exercise as a co-therapy for FM patients. In this context, the latest developments in research on anti-inflammatory effects of exercise are also reviewed and discussed. To find out what is known about the connection between benefits of exercise for FM and anti-inflammatory effects of exercise, we carried out a PubMed search using the term "fibromyalgia" and "exercise" together with "inflammation", and no more than ten published articles were found (six of them reviews), which are also discussed. In the second part of the article we present a pilot investigation on a group of 14 female FM patients with a diagnosis of FM by a rheumatologist. They took part in a pool-aquatic program in warm water over a period of fourth months (three weekly 60-min sessions). Circulating inflammatory (IL-1beta, IL-2, IFNgamma, TNFalpha, IL-8, IL-6, IL-4, IL-10 and CRP) and neuroendocrine (NA and cortisol) markers were determined. FM patients showed higher circulating levels of IL-8, IFNgamma and CRP as well as cortisol and NA than age-matched healthy control women. After the exercise program, a significant decrease in IL-8, IFNgamma, and CRP were found, in parallel with a decrease in circulating concentrations of cortisol and increased levels of NA. The results confirm an elevated "inflammatory status" in the FM syndrome and strengthen the hypothesis that the benefits of exercise in FM patients are mediated, at least in part, by its anti-inflammatory effects. A better regulation of the cytokine-HPA axis feedback may be also involved.