Promoting prosocial behavior and self-regulatory skills in preschool children through a mindfulness-based kindness curriculum

PubMed Central

Flook, Lisa; Goldberg, Simon B.; Pinger, Laura; Davidson, Richard J.

2015-01-01

Self-regulatory abilities are robust predictors of important outcomes across the lifespan, yet they are rarely taught explicitly in school. Using a randomized controlled design, the present study investigated the effects of a 12-week mindfulness-based Kindness Curriculum (KC) delivered in a public school setting on executive function, self-regulation, and prosocial behavior in a sample of 68 preschool children. The KC intervention group showed greater improvements in social competence and earned higher report card grades in domains of learning, health, and social-emotional development, whereas the control group exhibited more selfish behavior over time. Interpretation of effect sizes overall indicate small to medium effects favoring the KC group on measures of cognitive flexibility and delay of gratification . Baseline functioning was found to moderate treatment effects with KC children initially lower in social competence and executive functioning demonstrating larger gains in social competence relative to the control group. These findings, observed over a relatively short intervention period, support the promise of this program for promoting self-regulation and prosocial behavior in young children. They also support the need for future investigation of program implementation across diverse settings. PMID:25383689

The Marshall Space Flight Center KC-135 zero gravity test program for FY 1982

NASA Technical Reports Server (NTRS)

Shurney, R. E. (Editor)

1983-01-01

During FY-82, researchers and experimenters from Marshall Space Flight Center (MSFC) conducted 11 separate investigations during 26.3 hr of testing aboard the KC-135 zero-gravity aircraft, based at Ellington Air force Base, Texas. Although this represented fewer hours than initially projected, all experiment and test objectives were met or exceeded. This Technical Memorandum compiles all results achieved by MSFC users during FY-82, a year considered to be highly productive.

Teacher in Space Christa McAuliffe on the KC-135 for zero-G training

NASA Image and Video Library

1986-01-08

S86-25191 (for release January 1986) --- The two representatives of the Teacher-in-Space Project continue their training program at the Johnson Space Center with an additional flight aboard NASA?s KC-135 ?zero gravity? aircraft. Sharon Christa McAuliffe, left, is prime crew payload specialist, and Barbara R. Morgan is in training as backup payload specialist. The photo was taken by Keith Meyers of New York Times. Photo credit: NASA

Consanguineous Marriage as a Risk Factor for Developing Keratoconus

PubMed Central

JAMALI, Hossein; BEIGI, Vahid; SADEGHI-SARVESTANI, Ali

2018-01-01

Heredity plays an important role in keratoconus (KC). Consanguineous marriage (CM) can affect the transmission of recessively inherited conditions. We aimed to investigate the role of consanguineous marriage in the development of KC. This study included two groups: the first group comprised 415 patients who underwent surgery for KC for the first time at Khalili University Hospital (Shiraz, Iran), between 2010 and 2014; the second group comprised 415 healthy individuals who served as age- and sex-matched controls for the patient group. All study subjects were from the Fars province in Iran. CM type was evaluated by a standard checklist in both groups. The mean inbreeding coefficient (α) was evaluated and compared between the two groups. The percentage of parental first-cousin marriages was 35.4% in the patient group and 18.3% in the control group. The mean inbreeding coefficient (α) was 0.0291 in the patient group and 0.0135 in the control group. Patients with KC had a significantly higher mean inbreeding coefficient (α) than controls (T = 8, df = 828, P < 0.001). Our study suggests that CM can play a role in the pathogenesis of KC. As this disease is among the most frequent ocular disorders in our country, CM should be considered by health care systems within their screening programs. PMID:29644240

Is Children's Programming Improving?

ERIC Educational Resources Information Center

Potter, Rosemary Lee

1979-01-01

Susan Futterman, a former teacher and early childhood specialist for Action for Children's Television, comments on changing formats for children's programs, as well as on the role of educators in using television as a learning vehicle. (Editor/KC)

U.S. Spacesuit Knowledge Capture Accomplishments in Fiscal Years 2012 and 2013

NASA Technical Reports Server (NTRS)

Chullen, Cinda; Oliva, Vladenka R.

2014-01-01

The NASA U.S. spacesuit knowledge capture (KC) program has been in operations since the beginning 2008. The program was designed to augment engineers and others with information about spacesuits in a historical way. A multitude of seminars have captured spacesuit history and knowledge over the last six years of the programs existence. Subject matter experts have provided lectures and were interviewed to help bring the spacesuit to life so that lessons learned will never be lost. As well, the program concentrated in reaching out to the public and industry by making the recorded events part of the public domain through the NASA technical library via You Tube media. The U.S. spacesuit KC topics have included lessons learned from some of the most prominent spacesuit experts and spacesuit users including current and former astronauts. The events have enriched the spacesuit legacy knowledge from Gemini, Apollo, Skylab, Space Shuttle and International Space Station Programs. As well, expert engineers and scientists have shared their challenges and successes to be remembered. The last few years have been some of the most successful years of the KC program program's life with numerous recordings and releases to the public. It is evidenced by the thousands that have view the recordings online. This paper reviews the events accomplished and archived over Fiscal Years 2012 and 2013 and highlights a few of the most memorable ones. This paper also communicates ways to access the events that are available internally to NASA as well as in the public domain.

A Behaviorally-Oriented Activities Therapy Program for Adolescents.

ERIC Educational Resources Information Center

Chasanoff, Enid; Schrader, Carl

1979-01-01

A behaviorally-oriented activities therapy program was designed and implemented with adolescents who manifested problems at school, at home, and with peers. Techniques employed included: contingency contracting, assertiveness training, relaxation training, and cognitive restructuring. (Author/KC)

Hepatitis C virus core protein subverts the antiviral activities of human Kupffer cells.

PubMed

Tu, Zhengkun; Pierce, Robert H; Kurtis, Jonathan; Kuroki, Yoshio; Crispe, I Nicholas; Orloff, Mark S

2010-01-01

Kupffer cells (KC) are important innate immune cells of the liver, functioning as scavenging sinusoidal phagocytes and transducers of pattern recognition signals, including those of toll-like receptors (TLRs). The hepatitis C virus core protein (HCVc) engages TLR2 on peripheral blood monocytes and induces production of multiple inflammatory cytokines. We examined the effects of HCVc on human primary KC functions. KC were isolated from living donor allografts and stimulated with HCVc and/or ligands for TLRs. KC were examined for production of cytokines, expression of programmed death-ligand 1 (PD-L1), secretion of type 1 interferons (IFNs), and expression of the apoptosis-inducing protein tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL). HCVc acts as a ligand for TLR2 on human KC, inducing them to secrete interleukin (IL)-1beta, TNF-alpha, and IL-10 and up-regulate cell surface PD-L1. HCVc blocked TLR3-mediated secretion of IFN-alpha, IFN-beta, and cell surface expression of the cytotoxic molecule TRAIL. Inhibition of phosphoinositide 3 kinase with LY294002 blocked the up-regulation of PD-L1 by TLR ligands and the TLR3-specific induction of TRAIL and type 1 IFNs. KC are intravascular macrophages that are continuously exposed to, and tolerant of, bacterial TLR ligands, which are delivered via the portal circulation. By mimicking a bacterial TLR2 ligand and effectively blocking the TLR3-mediated, double-stranded RNA-induced antiviral response, HCVc might appear to exploit this unique aspect of immunity in the liver. Copyright 2010 AGA Institute. Published by Elsevier Inc. All rights reserved.

Word Processors: A Look at Four Popular Programs.

ERIC Educational Resources Information Center

Press, Larry

1980-01-01

Described are types of programs used for processing text (editors, print formatters, and word processors), followed by the comparison of four word-processing packages: Auto Scribe, Electric Pencil, Magic Want and Word Star. With the exception of Auto Scribe, all programs reviewed are CP/M versions. (KC)

Computer Series, 70.

ERIC Educational Resources Information Center

Moore, John W.

1986-01-01

Describes: (1) spreadheet programs (including VisiCalc) for experiments; (2) event-driven data acquisition (using ADALAB with an Acculab Infrared Spectometer); (3) microcomputer-controlled cyclic voltammetry; (4) inexpensive computerized experiments; (5) the "KC? Discoverer" program; and (6) MOLDOT (space-filling perspective diagrams of…

KC-135 on ramp

NASA Technical Reports Server (NTRS)

1958-01-01

The Boeing KC-135 Stratotanker, besides being used extensively in its primary role as an inflight aircraft refueler, has assisted in several projects at the NASA Dryden Flight Research Center, Edwards, California. In 1957 and 1958, Dryden was asked by what was then the Civil Aeronautics Administration (later absorbed into the Federal Aviation Administration (FAA) in 1958) to help establish new approach procedure guidelines on cloud-ceiling and visibility minimums for Boeing's first jet airliner, the B-707. Dryden used a KC-135 (the military variant of the 707), seen here on the runway at Edwards Air Force Base, to aid the CAA in these tests. In 1979 and 1980, Dryden was again involved with general aviation research with the KC-135. This time, a special wingtip 'winglet', developed by Richard Whitcomb of Langley Research Center, was tested on the jet aircraft. Winglets are small, nearly vertical fins installed on an airplane's wing tips to help produce a forward thrust in the vortices that typically swirl off the end of the wing, thereby reducing drag. This winglet idea was tested at the Dryden Flight Research Center on a KC-135A tanker loaned to NASA by the Air Force. The research showed that the winglets could increase an aircraft's range by as much as 7 percent at cruise speeds. The first application of NASA's winglet technology in industry was in general aviation business jets, but winglets are now being incorporated into most new commercial and military transport jets, including the Gulfstream III and IV business jets, the Boeing 747-400 and MD-11 airliners, and the C-17 military transport. In the 1980's, a KC-135 was used in support of the Space Shuttle program. Since the Shuttle was to be launched from Florida, researchers wanted to test the effect of rain on the sensitive thermal tiles. Tiles were mounted on special fixtures on an F-104 aircraft and a P-3 Orion. The F-104 was flown in actual rain conditions, and also behind the KC-135 spray tanker as it released water. The KC-135, however, proved incapable of simulating enough rain impact damage and was dropped from the tests.

KC-135A in flight - winglet study

NASA Technical Reports Server (NTRS)

1979-01-01

This Boeing KC-135 Stratotanker, besides being used extensively in its primary role as an inflight aircraft refueler, has assisted in several projects at the NASA Dryden Flight Research Center, Edwards, California. In 1979 and 1980, Dryden was involved with general aviation research with the KC-135. A special wingtip 'winglet', developed by Richard Whitcomb of Langley Research Center, was tested on the jet aircraft. Winglets are small, nearly vertical fins installed on an airplane's wing tips to help produce a forward thrust in the vortices that typically swirl off the end of the wing, thereby reducing drag. This winglet idea was tested at the Dryden Flight Research Center on a KC-135A tanker loaned to NASA by the Air Force. The research showed that the winglets could increase an aircraft's range by as much as 7 percent at cruise speeds. The first application of NASA's winglet technology in industry was in general aviation business jets, but winglets are now being incorporated into most new commercial and military transport jets, including the Gulfstream III and IV business jets, the Boeing 747-400 and MD-11 airliners, and the C-17 military transport. In 1957 and 1958, Dryden was asked by what was then the Civil Aeronautics Administration (later absorbed into the Federal Aviation Administration (FAA) in 1958) to help establish new approach procedure guidelines on cloud-ceiling and visibility minimums for Boeing's first jet airliner, the B-707. Dryden used a KC-135, the military variant of the 707, to aid the CAA in these tests. In the 1980's, a KC-135 was used in support of the Space Shuttle program. Since the Shuttle was to be launched from Florida, researchers wanted to test the effect of rain on the sensitive thermal tiles. Tiles were mounted on special fixtures on an F-104 aircraft and a P-3 Orion. The F-104 was flown in actual rain conditions, and also behind the KC-135 spray tanker as it released water. The KC-135, however, proved incapable of simulating enough rain impact damage and was dropped from the tests.

Effect of vernal keratoconjunctivitis on vitreous depth in patients with keratoconus.

PubMed

Cingü, Abdullah Kürşat; Kaya, Savaş; Çınar, Yasin; Şahin, Muhammed; Türkçü, Fatih Mehmet; Yüksel, Harun; Murat, Mehmet; Çaça, İhsan

2015-05-01

The aim of this study was to comparatively evaluate the vitreous depth (VD) of keratoconic eyes in patients with or without vernal keratoconjunctivitis (VKC). Eighty eyes of 80 consecutive keratoconus (KC) patients and 40 emmetropic control subjects were enrolled. KC patients were divided into two groups according to accompanying VKC (VKC-KC group and KC group). Mean outcome measures were best-corrected visual acuity (BCVA), spherical equivalent (SE), mean keratometry (Km), intraocular pressure (IOP), and axial length (AL) and its components. The eyes with the highest Km were selected for statistical analysis for each participant. There were 50, 30, and 40 patients in the VKC-KC group, KC group, and control group respectively. The KC group and VKC-KC group were similar in BCVA, SE, Km, CCT, ACD, LT, and IOP (p>0.05). The mean ACD was significantly lower in the control group when compared with the KC group and VKC-KC group. The mean AL and VD were significantly higher in VKC-KC group than those of KC group and the control group, whereas similar in KC and control groups (p>0.05). In the current study we showed that VKC-associated KC patients have significantly longer AL and VD when compared with KC patients without VKC. Posterior segment elongation in VKC-KC group may be associated with the type IV collagen destruction due to chronic longstanding inflammation in VKC patients.

Art, the Natural Sciences and a Museum.

ERIC Educational Resources Information Center

Unterberg, Adele Phyllis

1979-01-01

Described is a school-museum program which linked art and science through the study of small mammals and birds in relation to color, form, and communication. Art, audiovisual aids, research, readings, language, and communication were combined in this interdisciplinary program. (KC)

Woodwind Instrument Maintenance.

ERIC Educational Resources Information Center

Sperl, Gary

1980-01-01

The author presents a simple maintenance program for woodwind instruments which includes the care of tendon corks, the need for oiling keys, and methods of preventing cracks in woodwind instruments. (KC)

Stainless Steel NaK-Cooled Circuit (SNaKC) Fabrication and Assembly

NASA Technical Reports Server (NTRS)

Godfroy, Thomas J.

2007-01-01

An actively pumped Stainless Steel NaK Circuit (SNaKC) has been designed and fabricated by the Early Flight Fission Test Facility (EFF-TF) team at NASA's Marshall Space Flight Center. This circuit uses the eutectic mixture of sodium and potassium (NaK) as the working fluid building upon the experience and accomplishments of the SNAP reactor program from the late 1960's The SNaKC enables valuable experience and liquid metal test capability to be gained toward the goal of designing and building an affordable surface power reactor. The basic circuit components include a simulated reactor core a NaK to gas heat exchanger, an electromagnetic (EM) liquid metal pump, a liquid metal flow meter, an expansion reservoir and a drain/fill reservoir To maintain an oxygen free environment in the presence of NaK, an argon system is utilized. A helium and nitrogen system are utilized for core, pump, and heat exchanger operation. An additional rest section is available to enable special component testing m an elevated temperature actively pumped liquid metal environment. This paper summarizes the physical build of the SNaKC the gas and pressurization systems, vacuum systems, as well as instrumentation and control methods.

U.S. Spacesuit Knowledge Capture Accomplishments in Fiscal Years 2012 and 2013

NASA Technical Reports Server (NTRS)

Chullen, Cinda; Oliva, Vladenka R.

2014-01-01

The NASA U.S. Spacesuit Knowledge Capture (KC) program has existed since the beginning of 2008. The program was designed to augment engineers and other technical team members with historical spacesuit information to add to their understanding of the spacesuit, its evolution, its limitations, and its capabilities. Over 40 seminars have captured spacesuit history and knowledge over the last six years of the program's existence. Subject matter experts have provided lectures and some were interviewed to help bring the spacesuit to life so that lessons learned will never be lost. As well, the program concentrated in reaching out to the public and industry by making the recorded events part of the public domain through the NASA technical library through YouTube media. The U.S. Spacesuit KC topics have included lessons learned from some of the most prominent spacesuit experts and spacesuit users including current and former astronauts. The events have enriched the spacesuit legacy knowledge from Gemini, Apollo, Skylab, Space Shuttle and International Space Station Programs. As well, expert engineers and scientists have shared their challenges and successes to be remembered. Based on evidence by the thousands of people who have viewed the recordings online, the last few years have been some of the most successful years of the KC program's life with numerous digital recordings and public releases. This paper reviews the events accomplished and archived over Fiscal Years 2012 and 2013 and highlights a few of the most memorable ones. This paper also communicates ways to access the events that are available internally on the NASA domain as well as those released on the public domain.

Analysis of KC-46 Live-Fire Risk Mitigation Program Testing

DTIC Science & Technology

2012-03-01

the use of real hardware such as electrohydraulic actuators , electrical units, and converter regulators (Andrus, 2010). The only feasible method for...worked with the MQ-9 as a test engineer and analyst for the programs IOT &E, RQ-4 as lead engineer and program lead for the block 3 and the block 4

The Pollution Solution.

ERIC Educational Resources Information Center

Stephens, Lillian

1981-01-01

Presented are methods to help teachers continue the environmental awareness programs they have already started by providing up-to-date information and activities dealing with air pollution, water pollution, and solid waste disposal. (Author/KC)

Cryo-EM structure and biochemical analysis reveal the basis of the functional difference between human PI3KC3-C1 and -C2.

PubMed

Ma, Meisheng; Liu, Jun-Jie; Li, Yan; Huang, Yuwei; Ta, Na; Chen, Yang; Fu, Hua; Ye, Ming-Da; Ding, Yuehe; Huang, Weijiao; Wang, Jia; Dong, Meng-Qiu; Yu, Li; Wang, Hong-Wei

2017-08-01

Phosphatidylinositol 3-phosphate (PI3P) plays essential roles in vesicular trafficking, organelle biogenesis and autophagy. Two class III phosphatidylinositol 3-kinase (PI3KC3) complexes have been identified in mammals, the ATG14L complex (PI3KC3-C1) and the UVRAG complex (PI3KC3-C2). PI3KC3-C1 is crucial for autophagosome biogenesis, and PI3KC3-C2 is involved in various membrane trafficking events. Here we report the cryo-EM structures of human PI3KC3-C1 and PI3KC3-C2 at sub-nanometer resolution. The two structures share a common L-shaped overall architecture with distinct features. EM examination revealed that PI3KC3-C1 "stands up" on lipid monolayers, with the ATG14L BATs domain and the VPS34 C-terminal domain (CTD) directly contacting the membrane. Biochemical dissection indicated that the ATG14L BATs domain is responsible for membrane anchoring, whereas the CTD of VPS34 determines the orientation. Furthermore, PI3KC3-C2 binds much more weakly than PI3KC3-C1 to both PI-containing liposomes and purified endoplasmic reticulum (ER) vesicles, a property that is specifically determined by the ATG14L BATs domain. The in vivo ER localization analysis indicated that the BATs domain was required for ER localization of PI3KC3. We propose that the different lipid binding capacity is the key factor that differentiates the functions of PI3KC3-C1 and PI3KC3-C2 in autophagy.

Measurements of the Fuel Mileage of a KC-135 Aircraft with and Without Winglets

NASA Technical Reports Server (NTRS)

Temanson, G. E.

1982-01-01

The KC-135A Winglet Flight Research and Demonstration Program was a joint effort of the Air Force, NASA and the Boeing Military Airplane Company to flight test winglets on the KC-135A. The primary objective of the program was to verify the cruise performance improvements predicted by analysis and wind tunnel tests. Flight test data were obtained for winglets positioned at 15 deg cant/-2 deg incidence, 0 deg cant/-4 deg incidence, 15 deg cant/-4 deg incidence and for winglets off (baseline). Both fuel mileage and drag measurements were obtained. The 15 deg cant/-4 deg incidence winglet configuration provided the greatest performance improvement. The flight test measured fuel mileage improvement for a 0.78 Mach number was 3.1 percent at 8 x 10(5) pounds W/delta and 5.5 percent at 1.05 x 10(6) pounds W/delta. Correcting the flight measured data for surface pressure differences between wind tunnel and flight resulted in a fuel mileage improvement of 4.4 percent at 8 x 10(5) pounds W/delta and 7.2 percent at 1.05 x 10(6) pounds W/delta. The agreement between the fuel mileage and drag data was excellent.

Architectural Heritage: An Experiment in Montreal's Schools.

ERIC Educational Resources Information Center

Leveille, Chantal

1982-01-01

A museum program in Montreal encourages elementary and secondary school students to examine their surroundings and neighborhoods. Units focus on stained glass windows, houses, history of Montreal, the neighborhood, and architectural heritage. (KC)

Computers as Music Teachers.

ERIC Educational Resources Information Center

Taylor, Jack A.

1983-01-01

Peripheral components for music instruction include a music keyboard, a digital music synthesizer, and music listening devices. Computers can teach sight-singing, playing an instrument, dictation, and composition. Computer programs should be interactive with students. (KC)

Effects of skin-to-skin contact on autonomic pain responses in preterm infants.

PubMed

Cong, Xiaomei; Cusson, Regina M; Walsh, Stephen; Hussain, Naveed; Ludington-Hoe, Susan M; Zhang, Di

2012-07-01

The purpose of this randomized crossover trial was to determine the effects on autonomic responses in preterm infants of longer Kangaroo Care (30 minutes, KC30) and shorter KC (15 minutes, KC15) before and throughout heel stick compared with incubator care (IC). Beat-to-beat heart rate (HR) and spectral power analysis of heart rate variability, low frequency power (LF), high frequency power (HF), and LF/HF ratio were measured in 26 infants. HR changes from Baseline to Heel Stick were significantly less in KC30 and KC15 than in IC, and more infants had HR decrease in IC than in 2 KC conditions. In IC, LF and HF significantly increased from Baseline to Heel Stick and dropped from Heel Stick to Recovery; in 2 KC conditions, no changes across study phases were found. During Heel Stick, LF and HF were significantly higher in IC than in KC30. In all 3 conditions, LF/HF ratio decreased from Baseline to Heel Stick and increased to Recovery; no differences were found between IC and two KC conditions. Both longer and shorter KC before and throughout heel stick can stabilize HR response in preterm infants, and longer KC significantly affected infants' sympathetic and parasympathetic responses during heel stick compared with incubator care. This study showed that KC has a significant effect on reducing autonomic pain responses in preterm infants. The findings support that KC is a safe and effective pain intervention in the neonatal intensive care unit. Copyright © 2012 American Pain Society. Published by Elsevier Inc. All rights reserved.

Identification of QTLs for rice brown spot resistance in backcross inbred lines derived from a cross between Koshihikari and CH45.

PubMed

Matsumoto, Kengo; Ota, Yuya; Seta, Satomi; Nakayama, Yukinori; Ohno, Teppei; Mizobuchi, Ritsuko; Sato, Hiroyuki

2017-12-01

Rice brown spot (BS), caused by Bipolaris oryzae , is one of the major diseases of rice in Japan. Quantitative resistance has been observed in local cultivars (e.g., CH45), but no economically useful resistant variety has been bred. Using simple sequence repeat (SSR) polymorphic markers, we conducted quantitative trait locus (QTL) analysis of BS resistance in backcross inbred lines (BILs) from a cross between indica CH45 (resistant) and japonica Koshihikari (susceptible). On the basis of field disease evaluations in 2015 and 2016, four QTLs contributing to BS resistance were identified on chromosomes 2 ( qBSR2-kc ), 7 ( qBSR7-kc ), 9 ( qBSR9-kc ), and 11 ( qBSR11-kc ). The 'CH45' alleles at qBSR2-kc , qBSR7-kc , and qBSR11-kc and the 'Koshihikari' allele at qBSR9-kc increased resistance. The major QTL qBSR11-kc explained 23.0%-25.9% of the total phenotypic variation. Two QTLs ( qBSR9-kc and qBSR11-kc ) were detected in both years, whereas the other two were detected only in 2016. Genetic markers flanking these four QTLs will be powerful tools for marker-assisted selection to improve BS resistance.

78 FR 77118 - KC Small Hydro, LLC; Notice of Amended Preliminary Permit Application Accepted for Filing and...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-20

..., Motions To Intervene, and Competing Applications On May 28, 2013, KC Scoby Hydro, LLC, filed an... 28, 2013, application and sent an acceptance letter to KC Scoby Hydro, LLC. Subsequently, On October 28, 2013, KC Scoby Hydro, LLC, amended its preliminary permit application to change its name to KC...

General purpose free floating platform for KC-135 flight experimentation

NASA Technical Reports Server (NTRS)

Borchers, Bruce A.; Yendler, Boris S.; Kliss, Mark H.; Gonzales, Andrew A.; Edwards, Mark T.

1994-01-01

The Controlled Ecological Life Support Systems (CELSS) program is evaluating higher plants as a means of providing life support functions aboard space craft. These plant systems will be capable of regenerating air and water while meeting some of the food requirements of the crew. In order to grow plants in space, a series of systems are required to provide the necessary plant support functions. Some of the systems required for CELSS experiments are such that is is likely that existing technologies will require refinement, or novel technologies will need to be developed. To evaluate and test these technologies, a series of KC-135 precursor flights are being proposed. A general purpose free floating experiment platform is being developed to allow the KC-135 flights to be used to their fullest. This paper will outline the basic design for the CELSS Free Floating Test Bed (FFTB), and the requirements for the individual subsystems. Several preliminary experiments suitable for the free floater will also be discussed.

Telling Tales: On Evaluation and Narrative. Advances in Program Evaluation. Volume 6.

ERIC Educational Resources Information Center

Abma, Tineke, Ed.

Essays in this collection explore what a narrative perspective can mean for the practice of program evaluation. Narratives illuminate the value and meaning of a program or policy and can indicate the actions that need to be taken to improve it or to prevent failures in the future. The essays are: (1) "Introduction: Narrative Perspectives on…

KC-135A Winglet Flight Flutter Program

NASA Technical Reports Server (NTRS)

Kehoe, M. W.

1982-01-01

The evaluation techniques, results and conclusions for the flight flutter testing conducted on a KC-135A airplane configured with and without winglets are discussed. Test results are presented for the critical symmetric and antisymmetric modes for a fuel distribution that consisted of 10,000 pounds in each wing main tank and empty reserve tanks. The results indicated that a lightly damped oscillation was experienced for a winglet configuration of a 0 deg cant and -4 deg incidence. The effects of cant and incidence angle variation on the critical modes are also discussed. Lightly damped oscillations were not encountered for any other winglet cant and incidence angles tested.

The dissociation constants of the cytostatic bosutinib by nonlinear least-squares regression of multiwavelength spectrophotometric and potentiometric pH-titration data.

PubMed

Meloun, Milan; Nečasová, Veronika; Javůrek, Milan; Pekárek, Tomáš

2016-02-20

Potentiometric and spectrophotometric pH-titration of the multiprotic cytostatics bosutinib for dissociation constants determination were compared. Bosutinib treats patients with positive chronic myeloid leukemia. Bosutinib exhibits four protonatable sites in a pH range from 2 to 11, where two pK are well separated (ΔpK>3), while the other two are near dissociation constants. In the neutral medium, bosutinib occurs in the slightly water soluble form LH that can be protonated to the soluble cation LH4(3+). The molecule LH can be dissociated to still difficultly soluble anion L(-). The set of spectra upon pH from 2 to 11 in the 239.3-375.0nm was divided into two absorption bands: the first one from 239.3 to 290.5nm and the second from 312.3 to 375.0nm, which differ in sensitivity of chromophores to a pH change. Estimates of pK of the entire set of spectra were compared with those of both absorption bands. Due to limited solubility of bosutinib the protonation in a mixed aqueous-methanolic medium was studied. In low methanol content of 3-6% three dissociation constants can be reliably determined with SPECFIT/32 and SQUAD(84) and after extrapolation to zero content of methanol they lead to pKc1=3.43(12), pKc2=4.54(10), pKc3=7.56(07) and pKc4=11.04(05) at 25°C and pKc1=3.44(06), pKc2=5.03(08) pKc3=7.33(05) and pKc4=10.92(06) at 37°C. With an increasing content of methanol in solvent the dissociation of bosutinib is suppressed and the percentage of LH3(2+) decreases and LH prevails. From the potentiometric pH-titration at 25°C the concentration dissociation constants were estimated with ESAB pKc1=3.51(02), pKc2=4.37(02), pKc3=7.97(02) and pKc4=11.05(03) and with HYPERQUAD: pKc1=3.29(12), pKc2=4.24(10), pKc3=7.95(07) and pKc4=11.29(05). Copyright © 2015 Elsevier B.V. All rights reserved.

Culturally Adaptive Walking Intervention for Korean-Chinese Female Migrant Workers.

PubMed

Cho, Sunghye; Lee, Hyeonkyeong; Kim, Jung Hee; Lee, Meenhye; Lee, Young-Me

2017-05-01

Although the literature has commonly cited that development of culturally adaptive interventions is key to improving the health outcomes of culturally and linguistically diverse populations, there have been limited culturally adaptive walking interventions specific to Korean-Chinese (KC) migrants. The objective of this study is to describe the process in development of culturally adaptive walking interventions for KC female migrant workers, using the intervention mapping (IM) method. The culturally adaptive walking intervention was developed using the IM method, which is a stepwise theory and evidence-based approach for planning interventions. The IM method process has six steps, including needs assessment, formulation of change objectives, selection of theory-based methods and practical strategies, development of an intervention program, development of an adoption and implementation plan, and development of an evaluation design. The determinants of walking behavior, including knowledge, self-efficacy, social support, and acculturation, were identified through an extensive literature review, community leader interviews, and a survey of female KC migrant workers. Appropriate intervention methods and strategies were identified based on relevant theories. Acculturation was a determinant of exercise behavior, and various methods to improve cultural adaptation were identified in the context of the lifestyles and working environments of the target population. The IM method provided a foundation for creating a health intervention for KC female migrant workers. This method could easily be useful for health care providers working with other groups.

STS 61-B crewmembers training on the KC-135 in zero-G

NASA Image and Video Library

1985-08-21

STS 61-B crewmembers training on the KC-135 in zero-G. Views include Payload specialist Charles D. Walker attempting to down the lower torso of his extravehicular mobility unit (EMU) in zero-G in the KC-135. He is being assisted by other participants in the training (39135); Payload specialist Rodolfo Neri floating in midair during training in the KC-135 (39136,39138); Mission specialist Mary L. Cleave floating in midair during her training aboard the KC-135 (39137); Astronaut Bryan D. O'Connor assists Astronaut Sherwood C. Spring in completing his donning of the EMU in the KC-135 (39139); Technicians aid Spring with his EMU in the KC-135 (39140); O'Connor appears to be leaping up in zero-G aboard the KC-135 (39141); Astronaut Brewster Shaw is assisted by a technician to don his EMU (39142); Shaw is attempting to don the EMU gloves while O'Connor watches (39143); Shaw does jumping jacks while Neri attempts to travel down a rope guideline (39144).

Supplementing with Opuntia ficus-indica Mill and Dioscorea nipponica Makino extracts synergistically attenuates menopausal symptoms in estrogen-deficient rats.

PubMed

Ko, Byoung-Seob; Lee, Hye Won; Kim, Da Sol; Kang, Suna; Ryuk, Jin Ah; Park, Sunmin

2014-08-08

Prickly pear cactus grown in Korea (Opuntia ficus-indica Mill, KC) and Buchema (Dioscorea nipponica Makino, B) have been traditionally used in East Asia and South America to treat various metabolic diseases. The aim of the present study was to determine whether the extracts of KC, B, and KC+B can prevent the impairments of energy, glucose, lipid and bone homeostasis in estrogen-deficient ovariectomized (OVX) rats and to explore their mechanisms. OVX rats were divided into 4 groups and fed high fat diets supplemented with either 3% dextrin (control), 3% KC, 3% B or 1.5% KC+1.5% B. Sham rats were fed 3% dextrin. After 12 weeks of diet consumption, energy, lipid, glucose and bone metabolisms were analyzed and Wnt signaling in the femur and hepatic signaling were determined. OVX impaired energy, glucose and lipid metabolism and decreased uterine and bone masses. B and KC+B prevented the decrease in energy expenditure, especially from fat oxidation, in OVX rats, but did not affect food intake. KC+B and B reduced body weight and visceral fat levels, as compared to the OVX-control, by decreasing fat synthesis and inhibiting FAS and SREBP-1c expression. KC+B and B prevented the increases in serum lipid levels and insulin resistance by improving hepatic insulin signaling (pIRS→pAkt→pGSK-3β). KC and KC+B also prevented decreases in bone mineral density (BMD) in the femur and lumbar spine in OVX rats. This was related to decreased expressions of bone turnover markers such as serum osteocalcin, alkaline phosphatase (ALP) and bone-specific ALP levels, and increased serum P levels. KC and KC+B upregulated low-density lipoprotein receptor-related protein 5 and β-catenin in OVX rats, but suppressed the expression of dickkopf-related protein 1. B alone improved energy, lipid and glucose homeostasis, but not bone loss, whereas KC alone enhanced BMD, but not energy, lipid or glucose homeostasis. KC+B synergistically attenuated impairments of bone, energy, lipid and glucose metabolism by OVX, suggesting potential efficacy of the combination for alleviating menopausal symptoms. Copyright © 2014. Published by Elsevier Ireland Ltd.

Teaching Reading.

ERIC Educational Resources Information Center

Ricketts, Mary

1980-01-01

Described are five approaches to teaching reading: Language Experience, Modified Alphabet, Linguistic, Programmed, and Basal. It is suggested that a good teacher, well trained, certified in his or her profession, an active participant in professional organizations, can teach reading successfully using almost any approach. (KC)

Subtoxic Concentrations of Hepatotoxic Drugs Lead to Kupffer Cell Activation in a Human In Vitro Liver Model: An Approach to Study DILI

PubMed Central

Kegel, Victoria; Pfeiffer, Elisa; Burkhardt, Britta; Liu, Jia L.; Zeilinger, Katrin; Nüssler, Andreas K.; Seehofer, Daniel; Damm, Georg

2015-01-01

Drug induced liver injury (DILI) is an idiosyncratic adverse drug reaction leading to severe liver damage. Kupffer cells (KC) sense hepatic tissue stress/damage and therefore could be a tool for the estimation of consequent effects associated with DILI. Aim of the present study was to establish a human in vitro liver model for the investigation of immune-mediated signaling in the pathogenesis of DILI. Hepatocytes and KC were isolated from human liver specimens. The isolated KC yield was 1.2 ± 0.9 × 106 cells/g liver tissue with a purity of >80%. KC activation was investigated by the measurement of reactive oxygen intermediates (ROI, DCF assay) and cell activity (XTT assay). The initial KC activation levels showed broad donor variability. Additional activation of KC using supernatants of hepatocytes treated with hepatotoxic drugs increased KC activity and led to donor-dependent changes in the formation of ROI compared to KC incubated with supernatants from untreated hepatocytes. Additionally, a compound- and donor-dependent increase in proinflammatory cytokines or in anti-inflammatory cytokines was detected. In conclusion, KC related immune signaling in hepatotoxicity was successfully determined in a newly established in vitro liver model. KC were able to detect hepatocyte stress/damage and to transmit a donor- and compound-dependent immune response via cytokine production. PMID:26491234

Coral-inferred Variability of Upstream Kuroshio Current from 1953-2004 AD

NASA Astrophysics Data System (ADS)

Li, X.; Yi, L.; Shen, C. C.; Hsin, Y. C.

2016-12-01

The Kuroshio Current (KC), one of the most important western boundary currents in the North Pacific Ocean, strongly impacts regional climate in East Asia and upper-ocean thermal structure. However, the responses of KC to regional and remote climate forcing are poorly understood owing to lacking of long-term KC observations. Here, we present a sea surface temperature (SST) record from 1953 to 2004 AD derived from monthly skeletal δ18O data of a living coral Porites core, drilled in Nanwan, southern Taiwan (22°N, 121°E), located on the western front of the Upstream KC. The increased/reduced Kuroshio transport would generate stronger/weaker upwelling in Southern Taiwan, which can cause lower/higher SST. Agreement between dynamics of interannual coral δ18O and modern KC data shows that the regional coral δ18O can be used as a promising proxy for Upstream KC intensity. The KC-induced SST anomaly record reveals prominent interannual and decadal variability predominantly controlled by the bifurcation latitude of North Equatorial Current. We also find that the reconstructed KC intensity at east of Taiwan and south of Japan have nearly simultaneous interannual changes, suggesting the same dominant forcing(s) for the entire KC system. Additional work is needed to understand the KC system with respect to the interannual to decadal climate variability and the influences of global warming.

Evaluation of cardiopulmonary resuscitation techniques in microgravity

NASA Technical Reports Server (NTRS)

Billica, Roger; Gosbee, John; Krupa, Debra T.

1991-01-01

Cardiopulmonary resuscitation (CPR) techniques were investigated in microgravity with specific application to planned medical capabilities for Space Station Freedom (SSF). A KC-135 parabolic flight test was performed with the goal of evaluating and quantifying the efficacy of different types of microgravity CPR techniques. The flight followed the standard 40 parabola profile with 20 to 25 seconds of near-zero gravity in each parabola. Three experiments were involved chosen for their clinical background, certification, and practical experience in prior KC-135 parabolic flight. The CPR evaluation was performed using a standard training mannequin (recording resusci-Annie) which was used in practice prior to the actual flight. Aboard the KC-135, the prototype medical restraint system (MRS) for the SSF Health Maintenance Facility (HMF) was used for part of the study. Standard patient and crew restraints were used for interface with the MRS. During the portion of study where CPR was performed without MRS, a set of straps for crew restraint similar to those currently employed for the Space Shuttle program were used. The entire study was recorded via still camera and video.

45 CFR 309.170 - What statistical and narrative reporting requirements apply to Tribal IV-D programs?

Code of Federal Regulations, 2011 CFR

2011-10-01

... 45 Public Welfare 2 2011-10-01 2011-10-01 false What statistical and narrative reporting... (IV-D) PROGRAM Statistical and Narrative Reporting Requirements § 309.170 What statistical and... organizations must submit the following information and statistics for Tribal IV-D program activity and caseload...

45 CFR 309.170 - What statistical and narrative reporting requirements apply to Tribal IV-D programs?

Code of Federal Regulations, 2010 CFR

2010-10-01

... 45 Public Welfare 2 2010-10-01 2010-10-01 false What statistical and narrative reporting... (IV-D) PROGRAM Statistical and Narrative Reporting Requirements § 309.170 What statistical and... organizations must submit the following information and statistics for Tribal IV-D program activity and caseload...

Computer Series, 115.

ERIC Educational Resources Information Center

Birk, James P., Ed.

1990-01-01

Reviewed are six computer programs which may be useful in teaching college level chemistry. Topics include dynamic data storage in FORTRAN, "KC?DISCOVERER," pH of acids and bases, calculating percent boundary surfaces for orbitals, and laboratory interfacing with PT Nomograph for the Macintosh. (CW)

CXC chemokine KC fails to induce neutrophil infiltration and neoangiogenesis in a mouse model of myocardial infarction.

PubMed

Oral, Hasan; Kanzler, Isabella; Tuchscheerer, Nancy; Curaj, Adelina; Simsekyilmaz, Sakine; Sönmez, Tolga Taha; Radu, Eugen; Postea, Otilia; Weber, Christian; Schuh, Alexander; Liehn, Elisa A

2013-07-01

Chemokines and neutrophils, known as important players in the inflammatory cascade, also contribute to heart tissue recovery and scar formation after myocardial infarction (MI). The objective of this study was to determine the importance of ELR-containing CXC chemokine KC in neutrophil infiltration and neoangiogenesis, in a mouse model of chronic MI. MI was induced in mice divided in four groups: control (untreated), anti-KC "later" (anti-KC antibody injections started 4 days after MI and then delivered every 72 hours for 3 weeks, to inhibit angiogenesis), anti-KC "earlier" (anti-KC antibody injections 1 day before and 1 day after MI, to block neutrophil infiltration), anti-KC (anti-KC antibody injections 1 day before and 1 day after MI, and then every 72 hours for 3 weeks). The efficiency of the anti-KC treatment was determined by the measurement of KC serum concentration and immunofluorescence staining, in each of the four groups. Surprisingly, we did not find any difference in neutrophil infiltration in the infarcted area between untreated and treated animals. Moreover, the heart function, infarct size, and neoangiogenesis were not different between the four groups. As expected, a comparable anti-CXCR2 treatment of mice before and after MI was able to significantly reduce neutrophil infiltration into the infarcted area and angiogenesis, but also to reduce the infarction size after long or "later" treatment. The major finding of our study is that KC, a potent neutrophil chemoattractant and an established angiogenic factor, failed to interfere in the post-infarction inflammatory response, in wound healing and scar formation after MI. Therefore, these aspects need to be carefully taken into account when devising therapeutic strategies for myocardial infarction and ischemic cardiomyopathy. Copyright © 2013 Elsevier Ltd. All rights reserved.

E-4123

NASA Image and Video Library

1958-06-05

The Boeing KC-135 Stratotanker, besides being used extensively in its primary role as an inflight aircraft refueler, has assisted in several projects at the NASA Dryden Flight Research Center, Edwards, California. In 1957 and 1958, Dryden was asked by what was then the Civil Aeronautics Administration (later absorbed into the Federal Aviation Administration (FAA) in 1958) to help establish new approach procedure guidelines on cloud-ceiling and visibility minimums for Boeing's first jet airliner, the B-707. Dryden used a KC-135 (the military variant of the 707), seen here on the runway at Edwards Air Force Base, to aid the CAA in these tests. In 1979 and 1980, Dryden was again involved with general aviation research with the KC-135. This time, a special wingtip "winglet", developed by Richard Whitcomb of Langley Research Center, was tested on the jet aircraft. Winglets are small, nearly vertical fins installed on an airplane's wing tips to help produce a forward thrust in the vortices that typically swirl off the end of the wing, thereby reducing drag. This winglet idea was tested at the Dryden Flight Research Center on a KC-135A tanker loaned to NASA by the Air Force. The research showed that the winglets could increase an aircraft's range by as much as 7 percent at cruise speeds. The first application of NASA's winglet technology in industry was in general aviation business jets, but winglets are now being incorporated into most new commercial and military transport jets, including the Gulfstream III and IV business jets, the Boeing 747-400 and MD-11 airliners, and the C-17 military transport. In the 1980's, a KC-135 was used in support of the Space Shuttle program. Since the Shuttle was to be launched from Florida, researchers wanted to test the effect of rain on the sensitive thermal tiles. Tiles were mounted on special fixtures on an F-104 aircraft and a P-3 Orion. The F-104 was flown in actual rain conditions, and also behind the KC-135 spray tanker as it rel

Environmental controls on seasonal ecosystem evapotranspiration/potential evapotranspiration ratio as determined by the global eddy flux measurements

NASA Astrophysics Data System (ADS)

Liu, Chunwei; Sun, Ge; McNulty, Steven G.; Noormets, Asko; Fang, Yuan

2017-01-01

The evapotranspiration / potential evapotranspiration (AET / PET) ratio is traditionally termed as the crop coefficient (Kc) and has been generally used as ecosystem evaporative stress index. In the current hydrology literature, Kc has been widely used as a parameter to estimate crop water demand by water managers but has not been well examined for other types of ecosystems such as forests and other perennial vegetation. Understanding the seasonal dynamics of this variable for all ecosystems is important for projecting the ecohydrological responses to climate change and accurately quantifying water use at watershed to global scales. This study aimed at deriving monthly Kc for multiple vegetation cover types and understanding its environmental controls by analyzing the accumulated global eddy flux (FLUXNET) data. We examined monthly Kc data for seven vegetation covers, including open shrubland (OS), cropland (CRO), grassland (GRA), deciduous broad leaf forest (DBF), evergreen needle leaf forest (ENF), evergreen broad leaf forest (EBF), and mixed forest (MF), across 81 sites. We found that, except for evergreen forests (EBF and ENF), Kc values had large seasonal variation across all land covers. The spatial variability of Kc was well explained by latitude, suggesting site factors are a major control on Kc. Seasonally, Kc increased significantly with precipitation in the summer months, except in EBF. Moreover, leaf area index (LAI) significantly influenced monthly Kc in all land covers, except in EBF. During the peak growing season, forests had the highest Kc values, while croplands (CRO) had the lowest. We developed a series of multivariate linear monthly regression models for Kc by land cover type and season using LAI, site latitude, and monthly precipitation as independent variables. The Kc models are useful for understanding water stress in different ecosystems under climate change and variability as well as for estimating seasonal ET for large areas with mixed land covers.

75 FR 11527 - KC Hydro LLC; Notice of Competing Preliminary Permit Application Accepted for Filing and...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-11

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 13617-000] KC Hydro LLC..., 2010. On November 6, 2009, KC Hydro LLC filed an application for a preliminary permit, pursuant to... Sackheim, KC Hydro LLC, 5096 Cocoa Palm Way, Fair Oaks, CA 95628, phone: (916) 962-2271, e-mail: oregon...

Dual Role Airlift, Fee for Service?

DTIC Science & Technology

2011-06-01

XBB45R40B337 CHANL ETAR 02 DEC 2008 1140 KC10A 305AMW 6BB45R30B343 CHANL KWRI 08 DEC 2008 0230 18.8 4 KC10A 305AMW 6BB45R30B343 CHANL EGUN 09...LERT 29 JUL 2009 2130 1.5 3 KC10A 305AMW XVM101372174 SAAM EGUN 07 JUL 2009 0530 5.2 20 KC10A 305AMW 6JM109099188 SAAM KWRI 07 JUL 2009 1315...305AMW XAM111772209 SAAM OTBH 29 JUL 2009 1230 4.2 34 KC10A 305AMW XAM111772209 SAAM EGUN 30 JUL 2009 1600 KC10A 305AMW 6BW45Y50A214 CHANL

Finite-mode spectral model of homogeneous and isotropic Navier-stokes turbulence: a rapidly depleted energy cascade.

PubMed

Lévêque, E; Koudella, C R

2001-04-30

An eddy-viscous term is added to Navier-Stokes dynamics at wave numbers k greater than the inflection point kc of the energy flux F(log(k)). The eddy viscosity is fixed so that the energy spectrum satisfies E(k) = E(kc) (k/kc)(-3) for k>kc. This resulting forcing induces a rapid depletion of the energy cascade at k>kc. It is observed numerically that the model reproduces turbulence energetics at k< or =kc and statistics of two-point velocity correlations at scales r>lambda (Taylor microscale). Compared to a direct numerical simulation of R(lambda) = 130 an equivalent run with the present model results in a gain of a factor 20 in CPU time.

Kangaroo care: research results, and practice implications and guidelines.

PubMed

Ludington-Hoe, S M; Thompson, C; Swinth, J; Hadeed, A J; Anderson, G C

1994-02-01

Results of two studies of the effects of 2 to 3 hours of kangaroo care (KC), one a randomized trial of 25 premature infants in open-air cribs and the other a pilot of 6 premature infants who were at least 24 hours postextubation, who were cared for in incubators are reviewed. Both studies incorporated a pretest/posttest control group design. Heart rate and abdominal skin temperature rose for KC infants during KC. Heat loss did not occur during KC, and infants slept more during KC. Kangaroo care had a comforting effect on infants and their mothers. Apnea and periodic breathing episodes dropped during KC for incubator infants. Suggestions and guidelines for selection of infants and practice based on these studies are presented.

Air Force KC-X Tanker Aircraft Program: Background and Issues for Congress

DTIC Science & Technology

2010-03-12

obtained by CRS. 16 Gopal Ratnam and Alison Fitzgerald , “Northrop Declines Tanker Bid on...1-50. 19 Statement of General Duncan J. McNabb, USAF, Commander, United States Transportation Command, Before the House Armed Services Air & Land

DMA Modern Programming Environment Study.

DTIC Science & Technology

1980-01-01

capabilities. The centers are becoming increasingly dependent upon the computer and digital data in the fulfillment of MC&G goals. Successful application...ftticrcsrccessors C140 by Herbert AlteroDigital Citmmuncaticns C141 0 Structuredl Design ’-:orkshocr by Ned Chapin KC 156o Digital Systems En17lrceriirg CC 139 o3...on a programming environment. The study, which resulted in production of a paper entitled An EXEC 8 Programming Support Libary , contends that most of

Synthesis and application of polypyrrole/carrageenan nano-bio composite as a cathode catalyst in microbial fuel cells.

PubMed

Esmaeili, Chakavak; Ghasemi, Mostafa; Heng, Lee Yook; Hassan, Sedky H A; Abdi, Mahnaz M; Daud, Wan Ramli Wan; Ilbeygi, Hamid; Ismail, Ahmad Fauzi

2014-12-19

A novel nano-bio composite polypyrrole (PPy)/kappa-carrageenan(KC) was fabricated and characterized for application as a cathode catalyst in a microbial fuel cell (MFC). High resolution SEM and TEM verified the bud-like shape and uniform distribution of the PPy in the KC matrix. X-ray diffraction (XRD) has approved the amorphous structure of the PPy/KC as well. The PPy/KC nano-bio composites were then studied as an electrode material, due to their oxygen reduction reaction (ORR) ability as the cathode catalyst in the MFC and the results were compared with platinum (Pt) as the most common cathode catalyst. The produced power density of the PPy/KC was 72.1 mW/m(2) while it was 46.8 mW/m(2) and 28.8 mW/m(2) for KC and PPy individually. The efficiency of the PPy/KC electrode system is slightly lower than a Pt electrode (79.9 mW/m(2)) but due to the high cost of Pt electrodes, the PPy/KC electrode system has potential to be an alternative electrode system for MFCs. Copyright © 2014 Elsevier Ltd. All rights reserved.

Comparison of central corneal thickness measurements with a rotating scheimpflug camera, a specular microscope, optical low-coherence reflectometry, and ultrasound pachymetry in keratoconic eyes.

PubMed

Cinar, Yasin; Cingu, Abdullah Kursat; Turkcu, Fatih Mehmet; Cinar, Tuba; Sahin, Alparslan; Yuksel, Harun; Ari, Seyhmus

2015-03-01

To compare central corneal thickness (CCT) measurements with a rotating Scheimpflug camera (RSC), noncontact specular microscopy (SM), optical low-coherence reflectometry (OLCR), and ultrasonic pachymetry (UP) in keratoconus (KC) patients. In this prospective study, four CCT measurements taken with an RSC, SM, OLCR, and UP were compared in 81 eyes of 44 consecutive KC patients. The KC patients were divided into four subgroups according to Amsler-Krumeich's KC classification. The RSC and UP measurements of the CCT were not statistically significant in all the groups. Comparison of the SM vs. the OLCR measurements yielded statistically significant differences in all the KC patients and in all KC stages. In all the KC patients, RSC and OLCR showed a high correlation coefficient factor (r = 0.87, p = 0.000). CCT measurements with RSC are comparable to those achieved with UP. Compared with the other devices, according to SM measurements, the central cornea is thicker in all keratoconic eyes and in all KC grades, and it is thinner according to OLCR. RSC, UP, SM, and OLCR should not be used interchangeably in keratoconic eyes.

Effects of daily kangaroo care on cardiorespiratory parameters in preterm infants.

PubMed

Mitchell, A J; Yates, C; Williams, K; Hall, R W

2013-01-01

Kangaroo care (KC) has possible benefits for promoting physiological stability and positive developmental outcomes in preterm infants. The purpose of this study was to compare bradycardia and oxygen desaturation events in preterm infants in standard incubator care versus KC. Thirty-eight infants 27 to 30 weeks gestational age were randomly assigned to 2 hours of KC daily between days of life 5 to 10 or to standard incubator care. Infants were monitored for bradycardia (heart rate <80) or oxygen desaturation (<80%). Analysis of hourly events was based on three sets of data: standard care group 24 hours daily, KC group during incubator time 22 hours daily, and KC group during holding time 2 hours daily. The KC group had fewer bradycardia events per hour while being held compared to time spent in an incubator (p = 0.048). The KC group also had significantly fewer oxygen desaturation events while being held than while in the incubator (p = 0.017) and significantly fewer desaturation events than infants in standard care (p = 0.02). KC reduces bradycardia and oxygen desaturation events in preterm infants, providing physiological stability and possible benefits for neurodevelopmental outcomes.

Flow around circular cylinder oscillating at low Keulegan-Carpenter number

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sunahara, Shunji; Kinoshita, Takeshi

1994-12-31

This paper shows experimental results of hydrodynamic forces acting on a vertical circular cylinder oscillating sinusoidally at low frequencies in the still water and results of the flow visualization, to examine the flow around a circular cylinder, particularly the lift forces at low Keulegan-Carpenter number Kc. The instability of streaked flow of which section is mushroom shape is observed by flow visualization, and the flows are asymmetrical in some cases. The asymmetrical streaked flow may have a close relationship to the lift force at low Kc, Kc {le} 4 or 5. Asymmetrical mushroom vortex ring is visible for Kc {le}more » 1. The mushroom vortex ring is symmetrical, or the streaks of the rings arrange themselves alternately for 1 {le} Kc {le} 1.5. A clear ring of mushroom vortices is not formed due to diffusion of dye sheets, though a flow streaked with mushroom vortices is visible for 1.5 {le} Kc {le} 2.5 and for Kc {ge} 2.5 the flow is almost turbulent.« less

The 'Parent Circle' Peace Education Program: Does it Make Any Change?

PubMed

Braun-Lewensohn, Orna; Kitain, Boaz

2016-02-01

This study evaluated a peace education program facilitated by the 'parents circle family forum.' The program aims to expose Jewish and Palestinian-Arab adolescents to personal stories of bereavement as a result of the Israeli-Palestinian conflict. One hundred and sixty-four Jewish twelfth-grade adolescents from schools throughout Israel filled out questionnaires before the start of the educational program, and 135 Jewish adolescents filled out the same questionnaire up to a week after it ended. Questionnaires included empathy, anger, and legitimacy toward 'self' and 'others' narratives. Results indicate that, overall, there were not any significant differences before and after the educational program with regard to adolescents' attitudes toward 'self' and 'others' narratives. However, when examining differences between subgroups in Israeli society, significant differences between 'secular' and 'traditional' adolescents emerged. The attitudes of secular adolescents favored narratives of the 'others,' while the attitudes of the traditional adolescents favored the 'self' narratives. After the program, these differences diminished, meaning that the program had a different impact on each subgroup. The traditional adolescents became more favorable to the 'others' narratives, while the secular adolescents became more favorable to their own narratives. Results are discussed on the basis of the theoretical foundation of psychological impacts of intractable conflicts.

Peer Models Prevent Smoking among Pre-Adolescents.

ERIC Educational Resources Information Center

Williamson, John A.; Campbell, Lloyd P.

1980-01-01

It is suggested that the most desirable approach to combatting the smoking problem is to prevent youngsters from beginning to smoke, rather than prescribing treatment for them after they have become steady smokers. A program, which uses peer models, is described in this paper. (Author/KC)

Music for the Eyes: Slide/Tape and Video Techniques.

ERIC Educational Resources Information Center

Pembrook, Randall G.

1983-01-01

Slide/tape and videotape presentations can be used in music education to project music scores, document music tours and special programs, and present self-contained units for student mastery of specific skills. Materials needed, cost, and procedures for teacher-developed materials are outlined. (KC)

A story of change: The influence of narrative on African-Americans with diabetes

PubMed Central

Goddu, Anna P.; Raffel, Katie E.; Peek, Monica E.

2015-01-01

Objective To understand if narratives can be effective tools for diabetes empowerment, from the perspective of African-American participants in a program that improved diabetes self-efficacy and self-management. Methods In-depth interviews and focus groups were conducted with program graduates. Participants were asked to comment on the program's film, storytelling, and role-play, and whether those narratives had contributed to their diabetes behavior change. An iterative process of coding, analyzing, and summarizing transcripts was completed using the framework approach. Results African-American adults (n = 36) with diabetes reported that narratives positively influenced the diabetes behavior change they had experienced by improving their attitudes/beliefs while increasing their knowledge/skills. The social proliferation of narrative – discussing stories, rehearsing their messages with role-play, and building social support through storytelling – was reported as especially influential. Conclusion Utilizing narratives in group settings may facilitate health behavior change, particularly in minority communities with traditions of storytelling. Theoretical models explaining narrative's effect on behavior change should consider the social context of narratives. Practice implications Narratives may be promising tools to promote diabetes empowerment. Interventions using narratives may be more effective if they include group time to discuss and rehearse the stories presented, and if they foster an environment conducive to social support among participants. PMID:25986500

A story of change: The influence of narrative on African-Americans with diabetes.

PubMed

Goddu, Anna P; Raffel, Katie E; Peek, Monica E

2015-08-01

To understand if narratives can be effective tools for diabetes empowerment, from the perspective of African-American participants in a program that improved diabetes self-efficacy and self-management. In-depth interviews and focus groups were conducted with program graduates. Participants were asked to comment on the program's film, storytelling, and role-play, and whether those narratives had contributed to their diabetes behavior change. An iterative process of coding, analyzing, and summarizing transcripts was completed using the framework approach. African-American adults (n=36) with diabetes reported that narratives positively influenced the diabetes behavior change they had experienced by improving their attitudes/beliefs while increasing their knowledge/skills. The social proliferation of narrative - discussing stories, rehearsing their messages with role-play, and building social support through storytelling - was reported as especially influential. Utilizing narratives in group settings may facilitate health behavior change, particularly in minority communities with traditions of storytelling. Theoretical models explaining narrative's effect on behavior change should consider the social context of narratives. Narratives may be promising tools to promote diabetes empowerment. Interventions using narratives may be more effective if they include group time to discuss and rehearse the stories presented, and if they foster an environment conducive to social support among participants. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

Isolation and analysis of a multifunctional triterpene synthase KcMS promoter region from mangrove plant kandelia candel

NASA Astrophysics Data System (ADS)

Basyuni, M.; Wati, R.; Sulistiyono, N.; Sumardi; Oku, H.; Baba, S.; Sagami, H.

2018-03-01

Molecular cloning of Kandelia candel KcMS gene has previously been cloned and encoded a multifunctional triterpene synthase. In this study, the KcMS gene promoter was cloned through Genome walking, sequenced, and analyzed. A 1,358 bp genomic DNA fragment of KcMS promoter was obtained. PLACE and PlantCARE analysis of the KcMS promoter revealed that there was some regulatory elements in response to environmental signals and involved in the regulation of gene expression. Results showed that four kinds of elements are regulated by hormone binding, namely 2 MeJA-responsiveness elements (CGTCA-motif and TGACG-motif), the ABRE (TACGTG) involved in abscisic acid responsiveness, gibberellin-related GARE-motif (AAACAGA), and the TGA-element (AACGAC) as an auxin-responsive element. Several elements in the KcMS have been shown in other plants to be responsive to abiotic stress. These motifs were MBS (CAACTG), TC-rich repeats, and eight light responsive elements. The KcMS promoter was also involved in the activation of defense genes in plants such as HSE (AAAAAATTC) and four circadian control elements (CAANNNNATC). The presence of multipotential regulatory motifs suggested that KcMS may be involved in regulation of plant tolerance to several types of stresses.

Rotating Scheimpflug Imaging Indices in Different Grades of Keratoconus

PubMed Central

2016-01-01

Purpose. To evaluate accuracy of various Keratoconus (KC) screening indices, in relation to Topographic Keratoconus (TKC) grading. Setting. Al Watany Eye Hospital, Cairo, Egypt. Methods. Data of 103 normal (group 1) and 73 KC eyes (group 2), imaged by Pentacam (branded as Allegro Oculyzer), were analysed. Group 2 was divided into 2a: 14 eyes (TKC = 1, early KC), 2b: 25 eyes (TKC = 1 to 2 or 2, moderate KC), and 2c: 34 eyes (TKC = 2 to 3 up to 4, severe KC). Participants were followed up for six years to confirm diagnosis. Area under the receiver operating characteristic curve (AUROC) was calculated for evaluated curvature, elevation, and pachymetry indices with various reference shapes at different diameters. Results. When comparing normal to KC eyes, ten indices had significantly higher AUROC. Only five of them had significantly higher AUROC in early KC compared to normal corneas: Pachymetry Progression Index- (PPI-) Maximum (Max), Ambrósio's Relational Thickness- (ART-) Max, PPI-Max minus PPI-Minimum (Min), central corneal thickness (CCT), and diagonal decentration of thinnest point from the apex (AUROC = 0.690, 0.690, 0.687, 0.683, and 0.674, resp.). Conclusion. Generally, ten pachymetry and elevation-based indices had significantly higher AUROC. Five indices had statistically significant high AUROC when comparing early KC to normal corneas. PMID:27579178

Myths, Mummies and Museums.

ERIC Educational Resources Information Center

Norby, Shirley

1979-01-01

Greek mythology, Egyptian mummies, and the Metropolitan Museum of Art in New York City are the focus of a one-semester course given at the Sea Girt (New Jersey) Elementary School. It is an interdisciplinary program wherein students (grade 8) study ancient civilizations and do projects related to their studies. (KC)

Clio and the Marketplace: Teaching American Business History.

ERIC Educational Resources Information Center

Bracken, Alexander E.; Geelhoed, E. Bruce

1981-01-01

Presents rationale for including business history surveys and seminars in the curriculum of the contemporary business student. The approach is a pragmatic response to the need to expand and diversify history departments. Also, major corporations are good sources of corporate history and archival programs. (Author/KC)

High School Teachers Venture into Business World.

ERIC Educational Resources Information Center

Roper, Jack

1979-01-01

The author describes a program designed to place teachers in short-term positions in local businesses and industry, which plan would act as a motivation device in the wake of Proposition 13, and would ascertain whether teacher skills are sufficient to be employable outside of education. (KC)

TV as storyteller: how exposure to television narratives impacts at-risk preschoolers' story knowledge and narrative skills.

PubMed

Linebarger, Deborah L; Piotrowski, Jessica Taylor

2009-03-01

Educational media serve as informal educators within the home by supplementing young children's development. Substantial evidence documents the contributions of educational television to preschoolers' acquisition of a variety of skills; however, television's natural capacity as storyteller and the role it plays in preschoolers' early literacy development has been largely overlooked. This study examined the effects of viewing different TV program types on 311 at-risk preschoolers' story knowledge and narrative skills. Children were assigned to one of 4 viewing conditions (i.e. watching up to 40 episodes of a particular program type): no viewing; expository; embedded narrative; or traditional narrative. Story knowledge scores were higher for those viewing either narrative type. In contrast, viewing specific narrative types differentially affected the component skills of narrative competence. Story retelling and identification of explicit story events were higher after repeat viewing of embedded narratives while generating implicit story content was higher after repeat viewing of traditional narratives.

Contributions of microtubule rotation and dynamic instability to kinetochore capture

NASA Astrophysics Data System (ADS)

Sweezy-Schindler, Oliver; Edelmaier, Christopher; Blackwell, Robert; Glaser, Matt; Betterton, Meredith

2014-03-01

The capture of lost kinetochores (KCs) by microtubules (MTs) is a crucial part of prometaphase during mitosis. Microtubule dynamic instability has been considered the primary mechanism of KC capture, but recent work discovered that lateral KC attachment to pivoting MTs enabled rapid capture even with significantly reduced MT dynamics. We aim to understand the relative contributions of MT rotational diffusion and dynamic instability to KC capture, as well as KC capture through end-on and/or lateral attachment. Our model consists of rigid MTs and a spherical KC, which are allowed to diffuse inside a spherical nuclear envelope consistent with the geometry of fission yeast. For simplicity, we include a single spindle pole body, which is anchored to the nuclear membrane, and its associated polar MTs. Brownian dynamics treats the diffusion of the MTs and KC and kinetic Monte Carlo models stochastic processes such as dynamic instability. NSF 1546021.

Modulation of keratinocyte motility. Correlation with production of extracellular matrix molecules in response to growth promoting and antiproliferative factors.

PubMed Central

Nickoloff, B. J.; Mitra, R. S.; Riser, B. L.; Dixit, V. M.; Varani, J.

1988-01-01

Normal human epidermal keratinocytes (KC) grown under conditions that maintain the undifferentiated state are highly motile. Migration of these cells as measured in two different assays (migration out of an agarose drop explant, and into micropore filters in a modified Boyden chamber), is stimulated by fibronectin (FN) and to a lesser extent by thrombospondin (TSP). In contrast, laminin (LN) inhibits KC migration. Cultivation of the cells for 1 day under conditions that induce differentiation (ie, in the presence of 1.4 mM Ca2+) suppresses KC motility. A number of soluble growth modulating polypeptide factors also influence KC migration. Transforming growth factor-beta (TGF-beta) and epidermal growth factor (EGF) stimulate KC motility. These factors simultaneously induce KC production of FN and a significant portion of the stimulated motility can be inhibited with antibodies to FN. EGF and somatomedin-C (SM-C), but not TGF-beta, also stimulate TSP production while EGF and SM-C (but not TGF-beta) induce KC proliferation. In contrast to these factors, interferon-gamma (INF-gamma) inhibits KC production of both FN and TSP and concomitantly inhibits both motility and proliferation. These data suggest that KC properties essential for normal wound healing (ie, motility and proliferation) are regulated by both extracellular matrix molecules and soluble peptide factors. Finally, these effects of various growth promoting and antiproliferative factors on KCs may, in part, be mediated through alteration in the endogenous production of extracellular matrix molecules by KCs. Images Figure 2 PMID:2458044

KC-46 Tanker Aircraft: Program Generally Stable but Improvements in Managing Schedule Are Needed

DTIC Science & Technology

2013-02-27

testing, and supplier management. An important contractual requirement (and best practice ) is for Boeing to release 90 percent of the total engineering...design is stable, and manufacturing processes are mature. As we reported last year, while the program has implemented many acquisition best practices ...assessed the program’s acquisition plan to determine compliance with acquisition legislation and acquisition best practices . What GAO Recommends GAO

Coral record of variability in the upstream Kuroshio Current during 1953-2004

NASA Astrophysics Data System (ADS)

Li, Xiaohua; Liu, Yi; Hsin, Yi-Chia; Liu, Weiguo; Shi, Zhengguo; Chiang, Hong-Wei; Shen, Chuan-Chou

2017-08-01

The Kuroshio Current (KC), one of the most important western boundary currents in the North Pacific Ocean, strongly affects regional hydroclimate in East Asia and upper ocean thermal structure. Limited by few on-site observations, the responses of the KC to regional and remote climate forcings are still poorly understood. Here we use monthly coral δ18O data to reconstruct a KC transport record with annual to interannual resolution for the interval 1953-2004. The field site is located in southern Taiwan on the western flank of the upstream KC. Increased (reduced) KC transport would generate strong (weak) upwelling, resulting in relatively high (low) local coral δ18O. The upstream KC transport and downstream transport, off Tatsukushi Bay, Japan, covary on interannual and decadal time scales. This suggests common forcings, such as meridional drift of the North Equatorial Current bifurcation, or zonal climatic oscillations in the Pacific. The intensities of KC transport off southeastern and northeastern Taiwan are in phase before 1990 and antiphase after 1990. This difference may be due to a poleward shift of the subtropical western boundary current as a response to global warming.