Options for the Future of the US National Strong-Motion Program
,
1997-01-01
This report constitutes the requested 'Options Document'. This report considers three options. Option I assumes a constant level of financial support for Operating Expenses (OE) with not additional personnel support. Option II assumes a slight increase in OE support of $150K for FY 99 and beyond. Option III considers the role that a NSMP must play if the nation's urgent need to record the main earthquake at locations of significance for society is to be met. Two parts of Option III are considered. The first part of this option, termed Option III A, considers the role that strong-motion recording in and near man-made structures must play if a near-real time hazard initiative is to be implemented in the United States; The second part of Option III; termed Option III B, considers the scope of a NSMP needed to address society's needs to record the main earthquake in locations of significance for future public earthquake safety.
76 FR 10735 - Medicaid Program; Community First Choice Option
Federal Register 2010, 2011, 2012, 2013, 2014
2011-02-25
... Vol. 76 Friday, No. 38 February 25, 2011 Part III Department of Health and Human Services Centers for Medicare & Medicaid Services 42 CFR Part 441 Medicaid Program; Community First Choice Option...; [[Page 10736
Application of Real Options Theory to DoD Software Acquisitions
2009-02-20
Future Combat Systems Program. Washington, DC. U.S. Government Printing Office. Damodaran , A. (2007). Investment Valuation : The Options To Expand... valuation methodology, when enhanced and properly formulated around a proposed or existing software investment employing the spiral development approach...THIS PAGE INTENTIONALLY LEFT BLANK iii ABSTRACT The traditional real options valuation methodology, when enhanced and properly formulated
The Job Training Partnership Act and Computer-Assisted Instruction. Research Report 88-13.
ERIC Educational Resources Information Center
Education Turnkey Systems, Inc., Falls Church, VA.
A study sought to (1) determine the current and potential instructional application of computers in Job Training Partnership Act (JTPA) Titles II, III, and IV programs; and (2) present policy options that would increase the effective use of this technology in employment and training programs. Research methodology involved conducting an assessment…
College Today, Part III: College Closings. Options in Education Transcript: Program No. 121.
ERIC Educational Resources Information Center
George Washington Univ., Washington, DC. Inst. for Educational Leadership.
The closing of a college is the topic of the third in a series of four transcripts of radio programs on college today. The dialogue includes: a press conference at Lone Mountain College, with a discussion of financial problems by the president and comments by Lone Mountain's student body president, college vice president, art department chairman,…
75 FR 10873 - Energy Conservation Program: Energy Conservation Standards for Small Electric Motors
Federal Register 2010, 2011, 2012, 2013, 2014
2010-03-09
... design option to be technologically feasible if it is in use by the respective industry or if research.... Baseline Motor Performance 3. Higher Efficiency Motor Designs a. Electrical Steel b. Thermal Analysis c... a variety of provisions designed to improve energy efficiency. Part A of Title III (42 U.S.C. 6291...
Federal Register 2010, 2011, 2012, 2013, 2014
2010-07-09
... $1 Strike Program such that these options are now among some of the most popular products traded on... interested parties. III. Date of Effectiveness of the Proposed Rule Change and Timing for Commission Action... action is necessary or appropriate in the public interest, for the protection of investors, or otherwise...
40 CFR 63.1564 - What are my requirements for metal HAP emissions from catalytic cracking units?
Code of Federal Regulations, 2010 CFR
2010-07-01
... with the PM emission limit (Option 2); (iii) You can elect to comply with the Nickel (Ni) lb/hr emission limit (Option 3); or (iv) You can elect to comply with the Ni lb/1,000 lbs of coke burn-off... coke burn. ER11AP02.004 (iii) If you elect Option 3 in paragraph (a)(1)(iii) of this section, the Ni lb...
40 CFR 63.1564 - What are my requirements for metal HAP emissions from catalytic cracking units?
Code of Federal Regulations, 2011 CFR
2011-07-01
... with the PM emission limit (Option 2); (iii) You can elect to comply with the Nickel (Ni) lb/hr emission limit (Option 3); or (iv) You can elect to comply with the Ni lb/1,000 lbs of coke burn-off... coke burn. ER11AP02.004 (iii) If you elect Option 3 in paragraph (a)(1)(iii) of this section, the Ni lb...
CARE3MENU- A CARE III USER FRIENDLY INTERFACE
NASA Technical Reports Server (NTRS)
Pierce, J. L.
1994-01-01
CARE3MENU generates an input file for the CARE III program. CARE III is used for reliability prediction of complex, redundant, fault-tolerant systems including digital computers, aircraft, nuclear and chemical control systems. The CARE III input file often becomes complicated and is not easily formatted with a text editor. CARE3MENU provides an easy, interactive method of creating an input file by automatically formatting a set of user-supplied inputs for the CARE III system. CARE3MENU provides detailed on-line help for most of its screen formats. The reliability model input process is divided into sections using menu-driven screen displays. Each stage, or set of identical modules comprising the model, must be identified and described in terms of number of modules, minimum number of modules for stage operation, and critical fault threshold. The fault handling and fault occurence models are detailed in several screens by parameters such as transition rates, propagation and detection densities, Weibull or exponential characteristics, and model accuracy. The system fault tree and critical pairs fault tree screens are used to define the governing logic and to identify modules affected by component failures. Additional CARE3MENU screens prompt the user for output options and run time control values such as mission time and truncation values. There are fourteen major screens, many with default values and HELP options. The documentation includes: 1) a users guide with several examples of CARE III models, the dialog required to input them to CARE3MENU, and the output files created; and 2) a maintenance manual for assistance in changing the HELP files and modifying any of the menu formats or contents. CARE3MENU is written in FORTRAN 77 for interactive execution and has been implemented on a DEC VAX series computer operating under VMS. This program was developed in 1985.
Federal Register 2010, 2011, 2012, 2013, 2014
2010-02-10
... Effectiveness of Proposed Rule Change Relating to the Penny Pilot Program February 3, 2010. Pursuant to Section... Exchange filed the proposal as a ``non- controversial'' proposed rule change pursuant to Section 19(b)(3)(A)(iii) of the Act \\3\\ and Rule 19b-4(f)(6) thereunder.\\4\\ The Commission is publishing this notice to...
Applications of GIFTS III to Structural Engineering Problems.
The paper describes the latest version of the GIFTS SYSTEM (Graphics Oriented Interactive Finite Element Package for Time-Sharing), due for release...at the end of March 1976. The paper gives a description of the program modules available in the GIFTS library and the options available within its...framework. Examples are given to demonstrate the use of GIFTS in design-oriented applications. Some performance measurements are included. Amongst the
FY16 ASME High Temperature Code Activities
DOE Office of Scientific and Technical Information (OSTI.GOV)
Swindeman, M. J.; Jetter, R. I.; Sham, T. -L.
2016-09-01
One of the objectives of the ASME high temperature Code activities is to develop and validate both improvements and the basic features of Section III, Division 5, Subsection HB, Subpart B (HBB). The overall scope of this task is to develop a computer program to be used to assess whether or not a specific component under specified loading conditions will satisfy the elevated temperature design requirements for Class A components in Section III, Division 5, Subsection HB, Subpart B (HBB). There are many features and alternative paths of varying complexity in HBB. The initial focus of this task is amore » basic path through the various options for a single reference material, 316H stainless steel. However, the program will be structured for eventual incorporation all the features and permitted materials of HBB. Since this task has recently been initiated, this report focuses on the description of the initial path forward and an overall description of the approach to computer program development.« less
The Strategic Design of Reward Systems.
1982-10-01
AuTO1 , 8 CO NTRACT Ok .NANT NUMO lll , Edward E. Lawler III N-00014-81-K-0048 9 PERFORMING ORGANIZATION NAME AND ADORErS 10. PROGRAM ELEMENT...SUPPLEMENTARY NOTES .iL L:~ 19 KEY WORDS (Continue on reveres side It necessary and Identify by block number) A Pay, performance appraisal, motivation...retention, culture development:, and skill development are considered. The relationship between these object iwv and such design options as performance pay
Federal Register 2010, 2011, 2012, 2013, 2014
2011-07-26
... SECURITIES AND EXCHANGE COMMISSION [Release No. 34-64929; File No. SR-C2-2011-015] Self-Regulatory... Rule Change To Extend a Pilot Program Related to the Exchange's Automated Improvement Mechanism July 20...(b)(1). \\2\\ 17 CFR 240.19b-4. \\3\\ 15 U.S.C. 78s(b)(3)(A)(iii). \\4\\ 17 CFR 240.19b-4(f)(6). I. Self...
Goodman, Michael; Dana Flanders, W
2007-04-01
We compare methodological approaches for evaluating gene-environment interaction using a planned study of pediatric leukemia as a practical example. We considered three design options: a full case-control study (Option I), a case-only study (Option II), and a partial case-control study (Option III), in which information on controls is limited to environmental exposure only. For each design option we determined its ability to measure the main effects of environmental factor E and genetic factor G, and the interaction between E and G. Using the leukemia study example, we calculated sample sizes required to detect and odds ratio (OR) of 2.0 for E alone, an OR of 10 for G alone and an interaction G x E of 3. Option I allows measuring both main effects and interaction, but requires a total sample size of 1,500 cases and 1,500 controls. Option II allows measuring only interaction, but requires just 121 cases. Option III allows calculating the main effect of E, and interaction, but not the main effect of G, and requires a total of 156 cases and 133 controls. In this case, the partial case-control study (Option III) appears to be more efficient with respect to its ability to answer the research questions for the amount of resources required. The design options considered in this example are not limited to observational epidemiology and may be applicable in studies of pharmacogenomics, survivorship, and other areas of pediatric ALL research.
Federal Register 2010, 2011, 2012, 2013, 2014
2012-04-03
... Change Relating to the Equity Options Fees and Singly Listed Option Fee March 28, 2012. Pursuant to... entitled ``Equity Options Fees'' to assess Professionals an Options Surcharge in certain Multiply Listed Options; (ii) amend Section III \\4\\ of the Fee Schedule entitled ``Singly Listed Options'' to specify...
DOE Office of Scientific and Technical Information (OSTI.GOV)
Swindeman, M. J.; Jetter, R. I.; Sham, T. -L.
One of the objectives of the high temperature design methodology activities is to develop and validate both improvements and the basic features of ASME Boiler and Pressure Vessel Code, Section III, Rules for Construction of Nuclear Facility Components, Division 5, High Temperature Reactors, Subsection HB, Subpart B (HBB). The overall scope of this task is to develop a computer program to aid assessment procedures of components under specified loading conditions in accordance with the elevated temperature design requirements for Division 5 Class A components. There are many features and alternative paths of varying complexity in HBB. The initial focus ofmore » this computer program is a basic path through the various options for a single reference material, 316H stainless steel. However, the computer program is being structured for eventual incorporation all of the features and permitted materials of HBB. This report will first provide a description of the overall computer program, particular challenges in developing numerical procedures for the assessment, and an overall approach to computer program development. This is followed by a more comprehensive appendix, which is the draft computer program manual for the program development. The strain limits rules have been implemented in the computer program. The evaluation of creep-fatigue damage will be implemented in future work scope.« less
Vision for the Future of the US National Strong-Motion Program
,
1997-01-01
This document provides the requested vision for the future of the National Strong-Motion Program operated by the US Geological Survey. Options for operation of the program are presented in a companion document. Each of the three major charges of the EHRP, program council pertaining to the vision document is addressed here. The 'Vision Summary' through a series of answers to specific questions is intended to provide a complete synopsis of the committees response to program council charges. The Vision for the Future of the NSMP is presented as section III of the Summary. Analysis and detailed discussion supporting the answers in the summary are presented as sections organized according to the charges of the program council. The mission for the program is adopted from that developed at the national workshop entitled 'Research Needs for Strong Motion Data to Support Earthquake Engineering' sponsored by the National Science Foundation.
17 CFR 3.33 - Withdrawal from registration.
Code of Federal Regulations, 2012 CFR
2012-04-01
... customer, retail forex customer or option customer agreements, if any, have been terminated; (ii) That all customer, retail forex customer or option customer positions, if any, have been transferred on behalf of customers or option customers or closed; (iii) That all customer, retail forex customer or option customer...
Application of Real Options Theory to DoD Software Acquisitions
2009-08-01
words.) The traditional real options valuation methodology, when enhanced and properly formulated around a proposed or existing software investment...Std 239-18 - ii - THIS PAGE INTENTIONALLY LEFT BLANK - iii - Abstract The traditional real options valuation ...founder and CEO of Real Options Valuation , Inc., a consulting, training, and software development firm specializing in strategic real options
The standardized live patient and mechanical patient models--their roles in trauma teaching.
Ali, Jameel; Al Ahmadi, Khalid; Williams, Jack Ivan; Cherry, Robert Allen
2009-01-01
We have previously demonstrated improved medical student performance using standardized live patient models in the Trauma Evaluation and Management (TEAM) program. The trauma manikin has also been offered as an option for teaching trauma skills in this program. In this study, we compare performance using both models. Final year medical students were randomly assigned to three groups: group I (n = 22) with neither model, group II (n = 24) with patient model, and group III (n = 24) with mechanical model using the same clinical scenario. All students completed pre-TEAM and post-TEAM multiple choice question (MCQ) exams and an evaluation questionnaire scoring five items on a scale of 1 to 5 with 5 being the highest. The items were objectives were met, knowledge improved, skills improved, overall satisfaction, and course should be mandatory. Students (groups II and III) then switched models, rating preferences in six categories: more challenging, more interesting, more dynamic, more enjoyable learning, more realistic, and overall better model. Scores were analyzed by ANOVA with p < 0.05 being considered statistically significant. All groups had similar scores (means % +/- SD)in the pretest (group I - 50.8 +/- 7.4, group II - 51.3 +/- 6.4, group III - 51.1 +/- 6.6). All groups improved their post-test scores but groups II and III scored higher than group I with no difference in scores between groups II and III (group I - 77.5 +/- 3.8, group II - 84.8 +/- 3.6, group III - 86.3 +/- 3.2). The percent of students scoring 5 in the questionnaire are as follows: objectives met - 100% for all groups; knowledge improved: group I - 91%, group II - 96%, group III - 92%; skills improved: group I - 9%, group II - 83%, group III - 96%; overall satisfaction: group I - 91%, group II - 92%, group III - 92%; should be mandatory: group I - 32%, group II - 96%, group III - 100%. Student preferences (48 students) are as follows: the mechanical model was more challenging (44 of 48); more interesting (40 of 48); more dynamic (46 of 48); more enjoyable (48 of 48); more realistic (32/48), and better overall model (42 of 48). Using the TEAM program, we have demonstrated that improvement in knowledge and skills are equally enhanced by using mechanical or patient models in trauma teaching. However, students overwhelmingly preferred the mechanical model.
45 CFR 1306.34 - Combination program option.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 45 Public Welfare 4 2010-10-01 2010-10-01 false Combination program option. 1306.34 Section 1306... START PROGRAM HEAD START STAFFING REQUIREMENTS AND PROGRAM OPTIONS Head Start Program Options § 1306.34 Combination program option. (a) Combination program option requirements: (1) Grantees implementing a...
All Roads Lead to Rome: Update on Rome III Criteria and New Treatment Options
Shih, David Q.; Kwan, Lola Y.
2010-01-01
The recently published Rome III criteria reflect current understanding of functional gastrointestinal disorders. These criteria include definitions of these conditions and their pathophysiologic subtypes and offer guidelines for their management. At the 2006 Annual Scientific Meeting of the American College of Gastroenterology, a panel of experts discussed these criteria as they pertain to irritable bowel syndrome, functional dyspepsia, and chronic constipation. This article reviews the panel’s findings, highlights the differences between the Rome II and III criteria, and summarizes best treatment options currently available to practitioners and their patients. PMID:21544252
Thermal neutron detector and gamma-ray spectrometer utilizing a single material
Stowe, Ashley; Burger, Arnold; Lukosi, Eric
2017-05-02
A combined thermal neutron detector and gamma-ray spectrometer system, including: a detection medium including a lithium chalcopyrite crystal operable for detecting thermal neutrons in a semiconductor mode and gamma-rays in a scintillator mode; and a photodetector coupled to the detection medium also operable for detecting the gamma rays. Optionally, the detection medium includes a .sup.6LiInSe.sub.2 crystal. Optionally, the detection medium comprises a compound formed by the process of: melting a Group III element; adding a Group I element to the melted Group III element at a rate that allows the Group I and Group III elements to react thereby providing a single phase I-III compound; and adding a Group VI element to the single phase I-III compound and heating; wherein the Group I element includes lithium.
24 CFR Appendix III to Subpart B... - Certification of Homebuyer Status
Code of Federal Regulations, 2011 CFR
2011-04-01
... Description Pt. 904, Subpt. B, App. III Appendix III to Subpart B of Part 904—Certification of Homebuyer... payment of the purchase price, exercise the option to purchase the Home in accordance with and subject to...
24 CFR Appendix III to Subpart B... - Certification of Homebuyer Status
Code of Federal Regulations, 2010 CFR
2010-04-01
... Description Pt. 904, Subpt. B, App. III Appendix III to Subpart B of Part 904—Certification of Homebuyer... payment of the purchase price, exercise the option to purchase the Home in accordance with and subject to...
45 CFR 1306.33 - Home-based program option.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 45 Public Welfare 4 2013-10-01 2013-10-01 false Home-based program option. 1306.33 Section 1306.33... PROGRAM HEAD START STAFFING REQUIREMENTS AND PROGRAM OPTIONS Head Start Program Options § 1306.33 Home-based program option. (a) Grantees implementing a home-based program option must: (1) Provide one home...
45 CFR 1306.33 - Home-based program option.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 45 Public Welfare 4 2014-10-01 2014-10-01 false Home-based program option. 1306.33 Section 1306.33... PROGRAM HEAD START STAFFING REQUIREMENTS AND PROGRAM OPTIONS Head Start Program Options § 1306.33 Home-based program option. (a) Grantees implementing a home-based program option must: (1) Provide one home...
45 CFR 1306.33 - Home-based program option.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 45 Public Welfare 4 2012-10-01 2012-10-01 false Home-based program option. 1306.33 Section 1306.33... PROGRAM HEAD START STAFFING REQUIREMENTS AND PROGRAM OPTIONS Head Start Program Options § 1306.33 Home-based program option. (a) Grantees implementing a home-based program option must: (1) Provide one home...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-03-24
...-Settled Foreign Currency Option Fees, in Section III of the Fee Schedule, with Singly Listed Options \\3...\\. The Exchange currently assesses fees for sector index options and U.S. Dollar-Settled foreign currency... U.S. Dollar-Settled Foreign Currency Option Fees.'' \\4\\ BKX represents the KBW Bank Index. \\5\\ RUT...
17 CFR 3.33 - Withdrawal from registration.
Code of Federal Regulations, 2013 CFR
2013-04-01
... all customer, retail forex customer or option customer agreements, if any, have been terminated; (ii) That all customer, retail forex customer or option customer positions, if any, have been transferred on behalf of customers or option customers or closed; (iii) That all customer, retail forex customer or...
17 CFR 3.33 - Withdrawal from registration.
Code of Federal Regulations, 2014 CFR
2014-04-01
... all customer, retail forex customer or option customer agreements, if any, have been terminated; (ii) That all customer, retail forex customer or option customer positions, if any, have been transferred on behalf of customers or option customers or closed; (iii) That all customer, retail forex customer or...
A Selected Annotated Bibliography on Work Time Options.
ERIC Educational Resources Information Center
Ivantcho, Barbara
This annotated bibliography is divided into three sections. Section I contains annotations of general publications on work time options. Section II presents resources on flexitime and the compressed work week. In Section III are found resources related to these reduced work time options: permanent part-time employment, job sharing, voluntary…
Azamian, Zeinab; Shirban, Farinaz
2016-01-01
It is very difficult to diagnose and treat Class III malocclusion. This type of malocclusion involves a number of cranial base and maxillary and mandibular skeletal and dental compensation components. In Class III malocclusion originating from mandibular prognathism, orthodontic treatment in growing patients is not a good choice and in most cases orthognathic surgery is recommended after the end of growth. Approximately 30–40% of Class III patients exhibit some degree of maxillary deficiency; therefore, devices can be used for maxillary protraction for orthodontic treatment in early mixed dentition. In cases in which dental components are primarily responsible for Class III malocclusion, early therapeutic intervention is recommended. An electronic search was conducted using the Medline database (Entrez PubMed), the Cochrane Collaboration Oral Health Group Database of Clinical Trials, Science Direct, and Scopus. In this review article, we described the treatment options for Class III malocclusion in growing patient with an emphasis on maxillary protraction. It seems that the most important factor for treatment of Class III malocclusion in growing patient is case selection. PMID:27144056
Conversion of LARSYS III.1 to an IBM 370 computer
NASA Technical Reports Server (NTRS)
Williams, G. N.; Leggett, J.; Hascall, G. A.
1975-01-01
A software system for processing multispectral aircraft or satellite data (LARSYS) was designed and written at the Laboratory for Applications of Remote Sensing at Purdue University. This system, being implemented on an IBM 360/67 computer utilizing the Cambridge Monitor System, is of an interactive nature. TAMU LARSYS maintains the essential capabilities of Purdue's LARSYS. The machine configuration for which it has been converted is an IBM-compatible Amdahl 470V/6 computer utilizing the time sharing option of the currently implemented OS/VS2 Operating System. Due to TSO limitations, the NASA-JSC deliverable TAMU LARSYS is comprised of two parts. Part one is a TSO Control Card Checker for LARSYS control cards, and part two is a batch version of LARSYS. Used together, they afford most of the capabilities of the original LARSYS III.1. Additionally, two programs have been written by TAMU to support LARSYS processing. The first is an ERTS-to-MIST conversion program used to convert ERTS data to the LARSYS input form, the MIST tape. The second is a system runtable code which maintains tape/file location information for the MIST data sets.
45 CFR 1306.32 - Center-based program option.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 45 Public Welfare 4 2010-10-01 2010-10-01 false Center-based program option. 1306.32 Section 1306... START PROGRAM HEAD START STAFFING REQUIREMENTS AND PROGRAM OPTIONS Head Start Program Options § 1306.32 Center-based program option. (a) Class size. (1) Head Start classes must be staffed by a teacher and an...
2014-09-04
This final rule changes the meaningful use stage timeline and the definition of certified electronic health record technology (CEHRT) to allow options in the use of CEHRT for the EHR reporting period in 2014. It also sets the requirements for reporting on meaningful use objectives and measures as well as clinical quality measure (CQM) reporting in 2014 for providers who use one of the CEHRT options finalized in this rule for their EHR reporting period in 2014. In addition, it finalizes revisions to the Medicare and Medicaid EHR Incentive Programs to adopt an alternate measure for the Stage 2 meaningful use objective for hospitals to provide structured electronic laboratory results to ambulatory providers; to correct the regulation text for the measures associated with the objective for hospitals to provide patients the ability to view online, download, and transmit information about a hospital admission; and to set a case number threshold exemption for CQM reporting applicable for eligible hospitals and critical access hospitals (CAHs) beginning with FY 2013. Finally, this rule finalizes the provisionally adopted replacement of the Data Element Catalog (DEC) and the Quality Reporting Document Architecture (QRDA) Category III standards with updated versions of these standards.
New Therapies Offer Valuable Options for Patients with Melanoma
Two phase III clinical trials of new therapies for patients with metastatic melanoma presented in June at the 2011 ASCO conference confirmed that vemurafenib and ipilimumab (Yervoy™) offer valuable new options for the disease.
Professionals' and laypersons' appreciation of various options for Class III surgical correction.
Fabré, M; Mossaz, C; Christou, P; Kiliaridis, S
2010-08-01
The objectives of this study were to evaluate the assessments of maxillofacial surgeons, orthodontists, and laypersons on the predicted aesthetic outcome of various surgical options in Class III correction and the associations between certain initial cephalometric values and the judges' preferred option. Pre-surgical lateral headfilms and coloured profile photographs of 18 skeletal Class III Caucasian adult patients (10 males and 8 females) with a mean age of 24.5 years were used. The headfilms were hand traced and digitized. Conventional cephalometric analysis was performed. Computerized predictions of three surgical options, mandibular setback, Le Fort I advancement, and bimaxillary surgery, were made. For each case, the pre-surgical profile photograph with the three predictions was presented on a printed page. The questionnaire was sent to 51 maxillofacial surgeons (response rate 45.1 per cent), 78 orthodontists (response rate 71.8 per cent), and 61 laypersons (response rate 100 per cent) to aesthetically evaluate the pre-surgical photographs and the surgical predictions by placing a mark along a 10-graded visual analogue scale (VAS) using a standard profile for calibration. Confidence interval was calculated for each patient. An independent samples t-test was used to detect initial cephalometric values associated with the judges' preferred option and analysis of variance/Tukey's honestly significant differences to evaluate differences between judges. Intra-observer reliability was assessed with a paired t-test. All treatment predictions led to improved scoring of facial aesthetics with the exception of the setback option for three patients. For 14 patients, general agreement for the preferred option existed between the three groups of judges. Laypersons tended to give lower improvement scores than professionals. Overjet, nasofacial, and nasomental angles were important in decision making between the mandibular setback and Le Fort I options (the more negative the overjet, the larger the nasofacial angle, the smaller the nasomental angle, the greater the preference for the Le Fort I option). Wits appraisal seemed to be important in decision making between the mandibular setback and bimaxillary options (the more negative the Wits appraisal, the greater the preference for the latter option).
Noar, Seth M.; Webb, Elizabeth M.; Van Stee, Stephanie K.; Redding, Colleen A.; Feist-Price, Sonja; Crosby, Richard; Troutman, Adewale
2011-01-01
New prevention options are urgently needed for African-Americans in the United States given the disproportionate impact of HIV/AIDS on this group. This combined with recent evidence supporting the efficacy of computer technology-based interventions in HIV prevention led our research group to pursue the development of a computer-delivered individually tailored intervention for heterosexually active African-Americans—the tailored information program for safer sex (TIPSS). In the current article, we discuss the development of the TIPSS program, including (i) the targeted population and behavior, (ii) theoretical basis for the intervention, (iii) design of the intervention, (iv) formative research, (v) technical development and testing and (vi) intervention delivery and ongoing randomized controlled trial. Given the many advantages of computer-based interventions, including low-cost delivery once developed, they offer much promise for the future of HIV prevention among African-Americans and other at-risk groups. PMID:21257676
Space Operations Center system analysis study extension. Volume 2: Programmatics and cost
NASA Technical Reports Server (NTRS)
1982-01-01
A summary of Space Operations Center (SOC) orbital space station costs, program options and program recommendations is presented. Program structure, hardware commonality, schedules and program phasing are considered. Program options are analyzed with respect to mission needs, design and technology options, and anticipated funding constraints. Design and system options are discussed.
45 CFR 1306.31 - Choosing a Head Start program option.
Code of Federal Regulations, 2013 CFR
2013-10-01
... program option, or a family child care option. (b) The program option chosen must meet the needs of the children and families as indicated by the community needs assessment conducted by the grantee. (c) When...
45 CFR 1306.31 - Choosing a Head Start program option.
Code of Federal Regulations, 2014 CFR
2014-10-01
... program option, or a family child care option. (b) The program option chosen must meet the needs of the children and families as indicated by the community needs assessment conducted by the grantee. (c) When...
45 CFR 1306.31 - Choosing a Head Start program option.
Code of Federal Regulations, 2012 CFR
2012-10-01
... program option, or a family child care option. (b) The program option chosen must meet the needs of the children and families as indicated by the community needs assessment conducted by the grantee. (c) When...
Durand, Céline; Duplantie, Andrée; Fortin, Marie-Chantal
2014-10-15
Kidney recipients in the O blood group are at a disadvantage in kidney exchange programs (KEPs) because they can only receive an organ from O blood group donors. A way to remedy this unfair situation is through altruistic unbalanced paired kidney exchange (AUPKE) where a compatible pair (CP) consisting of an O donor and a non-O recipient is invited to participate in a KEP. There is no established AUPKE program in Canada. The aim of this study was to gather transplant professionals' views on the conditions necessary for the implementation of an AUPKE program. Nineteen Canadian transplant professionals took part in semistructured interviews. The content of these interviews was analyzed using a qualitative data analysis method. Respondents' recommendations focused on the following: (i) the logistics of AUPKE (e.g., not delaying the transplantation for the CP, retrieving organs locally, providing a good quality organ to the CP, and maintaining anonymity); (ii) the transplantation teams (e.g., establishing a consensus among members and ensuring sufficient resources); (iii) information provided to CPs; and (iv) research (e.g., looking into all transplant options for O recipients, studying all potential impacts of KEPs and AUPKE). The respondents in our study made the following recommendations for the implementation of an AUPKE program: (i) CPs should not be disadvantaged, (ii) measures should be taken to ensure that all transplant team members agree to participate and that there are sufficient resources for implementation, (iii) comprehensive information should be provided to the CP, and (iv) further research is needed on AUPKE.
41 CFR 102-194.5 - What is the Standard and Optional Forms Management Program?
Code of Federal Regulations, 2010 CFR
2010-07-01
... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false What is the Standard and Optional Forms Management Program? 102-194.5 Section 102-194.5 Public Contracts and Property Management... PROGRAMS 194-STANDARD AND OPTIONAL FORMS MANAGEMENT PROGRAM § 102-194.5 What is the Standard and Optional...
75 FR 17412 - Cancer Therapy Evaluation Program Intellectual Property Option to Collaborator
Federal Register 2010, 2011, 2012, 2013, 2014
2010-04-06
... Program Intellectual Property Option to Collaborator AGENCY: National Cancer Institute (NCI), National... Evaluation Program (CTEP) INTELLECTUAL PROPERTY OPTION. The proposed policy, if finalized, would establish... recommended Intellectual Property Option and Institution Notification if they wish to be considered for...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-08-19
... Change Amending Commentary .07 to Rule 6.4 To Modify the Short-Term Option Series Program To Increase the... short-term option series (``Short-Term Option Series'' or ``STOS'') Program to increase the number of... program under their respective rules. \\3\\ A Short-Term Option Series is a series of an option class that...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-11-23
... Expanding the Short Term Option Series Program November 17, 2011. I. Introduction On September 28, 2011, The...,\\2\\ a proposed rule change to expand the Short Term Option Program (``Program'') to allow the NASDAQ Options Market (``NOM'' or ``Exchange'') to: (1) Select up to 30 option classes on which Short Term Option...
42 CFR 457.70 - Program options.
Code of Federal Regulations, 2010 CFR
2010-10-01
...) STATE CHILDREN'S HEALTH INSURANCE PROGRAMS (SCHIPs) ALLOTMENTS AND GRANTS TO STATES Introduction; State Plans for Child Health Insurance Programs and Outreach Strategies § 457.70 Program options. (a) Health... 42 Public Health 4 2010-10-01 2010-10-01 false Program options. 457.70 Section 457.70 Public...
Laznow, J; Daniel, J
1992-01-01
Under provision of the Clean Air Act Amendments of 1990 Title III, the EPA has proposed a regulation (Early Reduction Program) to allow a six-year compliance extension from Maximum Achievable Control Technology (MACT) standards for sources that voluntarily reduce emissions of Hazardous Air Pollutants (HAPs) by 90 percent or more (95 percent or more for particulates) from a base year of 1987 or later. The emission reduction must be made before the applicable MACT standard is proposed for the source category or be subject to an enforceable commitment to achieve the reduction by January 1, 1994 for sources subject to MACT standards prior to 1994. The primary purpose of this program is to encourage reduction of HAPs emissions sooner than otherwise required. Industry would be allowed additional time in evaluating emission reduction options and developing more cost-effective compliance strategies, although, under strict guidelines to ensure actual, significant and verifiable emission reductions occur.
Federal Register 2010, 2011, 2012, 2013, 2014
2013-12-11
... series expire (``Short Term Option Expiration Dates'') at one time; and (ii) state that additional series... Rule Change, as Modified by Amendment No. 1, Relating to the Short Term Option Series Program December... Exchange's Short Term Option Series Program (``Weeklys Program''). The proposed rule change was published...
Federal Register 2010, 2011, 2012, 2013, 2014
2010-08-31
... Rule Change Relating to Routing Fees, the Monthly Cap and Electronic Auctions August 25, 2010. Pursuant... Monthly Cap on equity option transaction fees; and (iii) clarify language relating to electronic auctions...-105. The Exchange also proposes to amend its Monthly Cap assessed on Registered Options Traders...
46 CFR 307.7 - Information required in report.
Code of Federal Regulations, 2010 CFR
2010-10-01
... information, and (viii) The keyword “MAREP”. If optional remarks are included, they must follow at the end of... (vi) The keyword “MAREP”. If optional remarks are included, they must follow at the end of the text... Radio Call Sign, (iii) Time at reported position, (iv) Latitude and longitude, and (v) The keyword...
Development of Internet algorithms and some calculations of power plant COP
NASA Astrophysics Data System (ADS)
Ustjuzhanin, E. E.; Ochkov, V. F.; Znamensky, V. E.
2017-11-01
The authors have analyzed Internet resources containing information on some thermodynamic properties of technically important substances (the water, the air etc.). There are considered databases those possess such resources and are hosted in organizations (Joint Institute for High Temperatures (Russian Academy of Sciences), Standartinform (Russia), National Institute of Standards and Technology (USA), Institute for Thermal Physics (Siberian Branch of the Russian Academy of Sciences), etc.). Currently, a typical form is an Internet resource that includes a text file, for example, it is a file containing tabulated properties, R = (ρ, s, h…), here ρ - the density, s - the entropy, h - the enthalpy of a substance. It is known a small number of Internet resources those have the following characteristic. The resource allows a customer to realize a number of options, for example: i) to enter the input data, Y = (p, T), here p - the pressure, T - the temperature, ii) to calculate R property using “an exe-file” program, iii) to copy the result X = (p, T, ρ, h, s, …). Recently, some researchers (including the authors of this report) have requested a software (SW) that is designed for R property calculations and has a form of an open interactive (OI) Internet resource (“a client function”, “template”). A computing part of OI resource is linked: 1) with a formula, which is applied to calculate R property, 2) with a Mathcad program, Code_1(R,Y). An interactive part of OI resource is based on Informatics and Internet technologies. We have proposed some methods and tools those are related to this part and let us: a) to post OI resource on a remote server, b) to link a client PC with the remote server, c) to implement a number of options to clients. Among these options, there are: i) to calculate R property at given Y arguments, ii) to copy mathematical formulas, iii) to copy Code_1(R,Y) as a whole. We have developed some OI - resources those are focused on sharing: a) SW that is used to design power plants, for an example, Code - GTP_1(Z,R,Y) and b) client functions those are aimed to determine R properties of the working fluid at fixed points of the thermodynamic cycle. The program let us calculate energy criteria, Z, including the internal coefficient of performance (COP) for a power plant. We have discussed OI resources, among them OI resource that includes Code - GTP_1(Z,R,Y) and connected with a complex power plant included: i) several gas turbines, i) several compressors etc.
Finishing occlusion in Class II or Class III molar relation: therapeutic Class II and III.
Nangia, A; Darendeliler, M A
2001-11-01
The most frequent extraction regime consists of the removal of upper and lower premolars. Depending on anchorage requirements, camouflage treatment options, surgical intervention, or the absence of teeth in only one arch, it may become necessary to finalize the occlusion with a one-dental-unit discrepancy between the upper and lower dental arches. Guidelines are presented for finishing occlusions in Class II or Class III molar relation.
Gstat: a program for geostatistical modelling, prediction and simulation
NASA Astrophysics Data System (ADS)
Pebesma, Edzer J.; Wesseling, Cees G.
1998-01-01
Gstat is a computer program for variogram modelling, and geostatistical prediction and simulation. It provides a generic implementation of the multivariable linear model with trends modelled as a linear function of coordinate polynomials or of user-defined base functions, and independent or dependent, geostatistically modelled, residuals. Simulation in gstat comprises conditional or unconditional (multi-) Gaussian sequential simulation of point values or block averages, or (multi-) indicator sequential simulation. Besides many of the popular options found in other geostatistical software packages, gstat offers the unique combination of (i) an interactive user interface for modelling variograms and generalized covariances (residual variograms), that uses the device-independent plotting program gnuplot for graphical display, (ii) support for several ascii and binary data and map file formats for input and output, (iii) a concise, intuitive and flexible command language, (iv) user customization of program defaults, (v) no built-in limits, and (vi) free, portable ANSI-C source code. This paper describes the class of problems gstat can solve, and addresses aspects of efficiency and implementation, managing geostatistical projects, and relevant technical details.
Federal Register 2010, 2011, 2012, 2013, 2014
2012-06-06
... Term Option Series Program (``STOS Program'') to permit, during the expiration week of an option class... rule to open for trading Short Term Option Series at $0.50 strike price intervals for option classes... Short Term Option Series at $0.50 strike price intervals for option classes that trade in one dollar...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-10-13
... Short Term Options Series Program October 6, 2011. Pursuant to Section 19(b)(1) of the Securities... Proposed Rule Change The Exchange proposes to amend its rules to expand the Short Term Option Series... Term Option Series Program (``STOS Program'') \\3\\ so that the Exchange may select twenty-five option...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-11-23
... Short Term Option Series Program November 17, 2011. I. Introduction On September 28, 2011, NASDAQ OMX...,\\2\\ a proposed rule change to expand the Short Term Option Program (``Program'') to allow the Exchange to: (1) Select up to 30 option classes on which Short Term Option Series (``STO Series'') may be...
Neutron imaging systems utilizing lithium-containing semiconductor crystals
Stowe, Ashley C.; Burger, Arnold
2017-04-25
A neutron imaging system, including: a plurality of Li-III-VI.sub.2 semiconductor crystals arranged in an array, wherein III represents a Group III element and VI represents a Group VI element; and electronics operable for detecting and a charge in each of the plurality of crystals in the presence of neutrons and for imaging the neutrons. Each of the crystals is formed by: melting the Group III element; adding the Li to the melted Group III element at a rate that allows the Li and Group III element to react, thereby providing a single phase Li-III compound; and adding the Group VI element to the single phase Li-III compound and heating. Optionally, each of the crystals is also formed by doping with a Group IV element activator.
Federal Register 2010, 2011, 2012, 2013, 2014
2011-12-15
... Title III of the Higher Education Act of 1965, as Amended (HEA), and Programs Under Title V of the HEA...: Programs authorized under Part A, Title III of the HEA: Strengthening Institutions Program (Part A SIP... AANAPISI). Programs authorized under Part F, Title III of the HEA: Hispanic- Serving Institutions Stem and...
Federal Register 2010, 2011, 2012, 2013, 2014
2012-11-14
... Title III of the Higher Education Act of 1965, as Amended (HEA), and Programs Under Title V of the HEA...: Programs authorized under Part A, Title III of the HEA: Strengthening Institutions Program (Part A SIP...). Programs authorized under Part F, Title III of the HEA: Hispanic- Serving Institutions STEM and...
DOE Office of Scientific and Technical Information (OSTI.GOV)
Coltrin, M.E.; Kee, R.J.; Rupley, F.M.
1996-05-01
This document is the user`s manual for the SURFACE CHEMKIN-III package. Together with CHEMKIN-III, this software facilitates the formation, solution, and interpretation of problems involving elementary heterogeneous and gas-phase chemical kinetics in the presence of a solid surface. The package consists of two major software components: an Interpreter and a Surface Subroutine Library. The Interpreter is a program that reads a symbolic description of a user-specified chemical reaction mechanism. One output from the Interpreter is a data file that forms a link to the Surface Subroutine Library, which is a collection of about seventy modular Fortran subroutines that may bemore » called from a user`s application code to return information on chemical production rates and thermodynamic properties. This version of SURFACE CHEMKIN-III includes many modifications to allow treatment of multi-fluid plasma systems, for example modeling the reactions of highly energetic ionic species with a surface. Optional rate expressions allow reaction rates to depend upon ion energy rather than a single thermodynamic temperature. In addition, subroutines treat temperature as an array, allowing an application code to define a different temperature for each species. This version of SURFACE CHEMKIN-III allows use of real (non-integer) stoichiometric coefficients; the reaction order with respect to species concentrations can also be specified independent of the reaction`s stoichiometric coefficients. Several different reaction mechanisms can be specified in the Interpreter input file through the new construct of multiple materials.« less
10 CFR 420.17 - Optional elements of State Energy Program plans.
Code of Federal Regulations, 2012 CFR
2012-01-01
... 10 Energy 3 2012-01-01 2012-01-01 false Optional elements of State Energy Program plans. 420.17 Section 420.17 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION STATE ENERGY PROGRAM Formula Grant Procedures § 420.17 Optional elements of State Energy Program plans. (a) Other appropriate activities or...
10 CFR 420.17 - Optional elements of State Energy Program plans.
Code of Federal Regulations, 2011 CFR
2011-01-01
... 10 Energy 3 2011-01-01 2011-01-01 false Optional elements of State Energy Program plans. 420.17 Section 420.17 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION STATE ENERGY PROGRAM Formula Grant Procedures § 420.17 Optional elements of State Energy Program plans. (a) Other appropriate activities or...
10 CFR 420.17 - Optional elements of State Energy Program plans.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 10 Energy 3 2010-01-01 2010-01-01 false Optional elements of State Energy Program plans. 420.17 Section 420.17 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION STATE ENERGY PROGRAM Formula Grant Procedures § 420.17 Optional elements of State Energy Program plans. (a) Other appropriate activities or...
10 CFR 420.17 - Optional elements of State Energy Program plans.
Code of Federal Regulations, 2013 CFR
2013-01-01
... 10 Energy 3 2013-01-01 2013-01-01 false Optional elements of State Energy Program plans. 420.17 Section 420.17 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION STATE ENERGY PROGRAM Formula Grant Procedures § 420.17 Optional elements of State Energy Program plans. (a) Other appropriate activities or...
10 CFR 420.17 - Optional elements of State Energy Program plans.
Code of Federal Regulations, 2014 CFR
2014-01-01
... 10 Energy 3 2014-01-01 2014-01-01 false Optional elements of State Energy Program plans. 420.17 Section 420.17 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION STATE ENERGY PROGRAM Formula Grant Procedures § 420.17 Optional elements of State Energy Program plans. (a) Other appropriate activities or...
Reducing the Deficit: Spending and Revenue Options
2011-03-01
the Conservation Reserve Program 25AgricultureOption 6 Reduce the Premium Subsidy in the Crop Insurance Program 26Option 7 Reduce by 20 Percentage...Graduate Students 31Option 11 Change the Interest Rate Structure for Student Loans 32HealthOption 12 Add a “Public Plan” to the Health Insurance Exchanges...Health Episodes Covered by Medicare 48Option 21 Reduce Medicare Costs by Changing the Cost-Sharing Structures for Medicare and Medigap Insurance 49Option
NASA Technical Reports Server (NTRS)
Dick, J. W.; Benda, B. J.
1975-01-01
User and programmer oriented documentation for the flexible body option of the Takeoff and Landing Analysis (TOLA) computer program are provided. The user information provides sufficient knowledge of the development and use of the option to enable the engineering user to successfully operate the modified program and understand the results. The programmer's information describes the option structure and logic enabling a programmer to make major revisions to this part of the TOLA computer program.
ERIC Educational Resources Information Center
Bonar, John R., Ed.; Hathway, James A., Ed.
This is the student's text of one unit of the Intermediate Science Curriculum Study (ISCS) for level III students (grade 9). This unit focuses on diversity in human populations, measurement, and data collection. Numerous activities are given and optional excursions encourage students to pursue a topic in greater depth. Data tables within the…
32 CFR 199.5 - TRICARE Extended Care Health Option (ECHO).
Code of Federal Regulations, 2010 CFR
2010-07-01
...-eligible dependents: (i) A spouse, child, or unmarried person (as described in § 199.3(b)(2)(i), (b)(2)(ii.... (ii) An abused dependent as described in § 199.3(b)(2)(iii). (iii) A spouse, child, or unmarried... member for over one-half of such dependent's support. (iv) A spouse, child, or unmarried person (as...
General Military Training: Standardization and Reduction Options
2012-01-01
pregnancy prevention (navy) n Y n Y n Y III SGLI (Marine Corps) n n n Y n Y III Table A.1—Continued Our Assessment of Topics That Meet the Approved...sensitive issues promotes trust and unit esprit de corps. The Army chooses to uti - lize time for CMT as an opportunity for a unit leader to mentor
Federal Register 2010, 2011, 2012, 2013, 2014
2011-02-15
... Rule Change To Expand the Short Term Option Series Program February 9, 2011. Pursuant to Section 19(b... Series Program. The text of the proposed rule change is available on the Exchange's Web site http://www... Term Option Series Program (``STOS Program'') \\3\\ so that the Exchange may select fifteen option...
Addition of flexible body option to the TOLA computer program, part 1
NASA Technical Reports Server (NTRS)
Dick, J. W.; Benda, B. J.
1975-01-01
This report describes a flexible body option that was developed and added to the Takeoff and Landing Analysis (TOLA) computer program. The addition of the flexible body option to TOLA allows it to be used to study essentially any conventional type airplane in the ground operating environment. It provides the capability to predict the total motion of selected points on the analytical methods incorporated in the program and operating instructions for the option are described. A program listing is included along with several example problems to aid in interpretation of the operating instructions and to illustrate program usage.
2015-10-28
The U.S. Office of Personnel Management (OPM) is issuing a final rule to amend the Federal Employees Health Benefits (FEHB) Program regulations regarding enrollment options following the termination of a plan or plan option.
34 CFR 300.110 - Program options.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 34 Education 2 2010-07-01 2010-07-01 false Program options. 300.110 Section 300.110 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND... DISABILITIES State Eligibility Other Fape Requirements § 300.110 Program options. The State must ensure that...
Federal Register 2010, 2011, 2012, 2013, 2014
2012-08-15
...; and (iii) establish a fee of $0.10 per contract for NYSE Amex Options Market Maker executions of SPY... than SPY would continue to pay the existing transaction charges, as provided in the Fee Schedule. 2... for SPY options are currently $0.25 per contract, which, when coupled with the proposed $0.10 per...
Code of Federal Regulations, 2010 CFR
2010-04-01
... grouping rules of paragraph (c)(2)(iii) of this section. Separate charts are provided for ages 55, 60, and...) Simplified presentations permitted—(A) Grouping of certain optional forms. Two or more optional forms of... starting date, a reasonable assumption for the age of the participant's spouse, or, in the case of a...
Generalized worry disorder: a review of DSM-IV generalized anxiety disorder and options for DSM-V.
Andrews, Gavin; Hobbs, Megan J; Borkovec, Thomas D; Beesdo, Katja; Craske, Michelle G; Heimberg, Richard G; Rapee, Ronald M; Ruscio, Ayelet Meron; Stanley, Melinda A
2010-02-01
Generalized anxiety disorder (GAD) has undergone a series of substantial classificatory changes since its first inclusion in DSM-III. The majority of these revisions have been in response to its poor inter-rater reliability and concerns that it may lack diagnostic validity. This article provides options for the revision of the DSM-IV GAD criteria for DSM-V. First, searches were conducted to identify the evidence that previous DSM Work Groups relied upon when revising the DSM-III-R GAD and the overanxious disorder classifications. Second, the literature pertaining to the DSM-IV criteria for GAD was examined. The review presents a number of options to be considered for DSM-V. One option is for GAD to be re-labeled in DSM-V as generalized worry disorder. This would reflect its hallmark feature. Proposed revisions would result in a disorder that is characterized by excessive anxiety and worry generalized to a number of events or activities for 3 months or more. Worry acts as a cognitive coping strategy that manifests in avoidant behaviors. The reliability and validity of the proposed changes could be investigated in DSM-V validity tests and field trials.
Vaxevanidou, K; Christou, C; Kremmydas, G F; Georgakopoulos, D G; Papassiopi, N
2015-03-01
In this study two different treatment options were investigated for the release of arsenic from a contaminated soil sample. The first option was based on the "bioaugmentation" principle and involved addition of a pure Fe(III)-reducing culture, i.e. Desulfuromonas palmitatis. The second option consisted in the "biostimulation" of indigenous bacteria and involved simple addition of nutrients. Due to the strong association of As with soil ferric oxides, the reductive dissolution of soil oxides by D. palmitatis lead to 45 % arsenic release in solution (2.15 mM). When only nutrients were supplied to the soil, the same amounts of Fe and As were dissolved with slower rates and most aqueous As was found to be in the trivalent state, indicating the presence of arsenate reducing species. The arsenate reducing microorganisms were enriched with successive cultures, using Na2HAsO4 as electron acceptor. The phylogenetic analysis revealed that the enriched microbial consortium contained Desulfosporosinus species, which are known arsenate reducers.
Thermann, Florian; Ukkat, Jörg; Wollert, Ulrich; Dralle, Henning; Brauckhoff, Michael
2007-11-01
Dialysis shunt-associated steal syndrome (DASS) is a rare complication of hemodialysis access (HA) which preferably occurs in brachial fistulas. Treatment options are discussed controversially. Aim of this study was to evaluate flow-controlled fistula banding. Patients treated between 2002 and 2006 were included in this prospective survey. According to a classification we established, patients were typed DASS I-III (I: short history, no dermal lesions; II: long history, skin lesions; III: long history, gangrene). Surgical therapy was HA banding including controlled reduction (about 50% of initial flow) of HA blood flow (patients type I and II). Patients with type III underwent closure of the HA. In 15 patients with relevant DASS, blood-flow-controlled banding was performed. In ten patients (all type I), banding led to restitution of the hand function while preserving the HA. In five patients (all type II), banding was not successful; in two patients, closure of the HA was performed eventually. In five patients (type III), primary closure of the HA was performed. Four patients with DASS type II but only two with DASS type I had diabetes mellitus (p = 0.006). Banding under blood flow control resulting in an approximately 50% reduction in the initial blood flow is an adequate therapeutic option in patients with brachial HA and type I-DASS. In type II-DASS, banding does not lead to satisfying results, more complex surgical options might be more successful. Diabetes is associated with poor HA outcome in case of DASS.
46 CFR 115.650 - Alternative Hull Examination (AHE) Program options: Divers or underwater ROV.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 46 Shipping 4 2010-10-01 2010-10-01 false Alternative Hull Examination (AHE) Program options... MORE THAN 49 PASSENGERS INSPECTION AND CERTIFICATION Hull and Tailshaft Examinations § 115.650 Alternative Hull Examination (AHE) Program options: Divers or underwater ROV. To complete your underwater...
46 CFR 176.650 - Alternative Hull Examination Program options: Divers or underwater ROV.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 46 Shipping 7 2010-10-01 2010-10-01 false Alternative Hull Examination Program options: Divers or...) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) INSPECTION AND CERTIFICATION Hull and Tailshaft Examinations § 176.650 Alternative Hull Examination Program options: Divers or underwater ROV. To complete the...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-10-06
... the Number of Series Permitted per Class in the Short Term Option Series Program September 30, 2011..., Incorporated proposes to amend Rules 5.5 and 24.9 to increase the number of Short Term Options Series that may be opened for each option class that participates in the Exchange's Short Term Option Series Program...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-08-19
... Amending Commentary .10 to Rule 903 To Modify the Short-Term Option Series Program To Increase the Number... option series (``Short-Term Option Series'' or ``STOS'') Program to increase the number of classes that... respective rules. \\3\\ A Short-Term Option Series is a series of an option class that is approved for listing...
ERIC Educational Resources Information Center
Reesman, Cilla J.
This technical assistance guide presents the various options available to state planners and managers in considering five elements of active grant management. Each element is treated in a separate chapter. Chapter 1 addresses issues surrounding the setting of policies that ensure that Title III grants complement state agendas. Chapter 2 concerns…
Non-extraction treatment of a Class III skeletal case.
Gonzalez, Bulmario
2009-01-01
Adult Class III Skeletal treatment options have generally included some form of surgery (Maxillary advancement in midface deficient cases and/or Mandibular set-back). This article discusses non-surgical treatment of an adult patient using the combined concepts of mandibular molar distalization enhanced with TADs and non-extraction camouflage dental correction through maxillary incisor protraction and mandibular incisor lingualization.
ERIC Educational Resources Information Center
Bonar, John R., Ed.; Hathway, James A., Ed.
This is the teacher's edition of one of the eight units of the Intermediate Science Curriculum Study (ISCS) for level III students (grade 9). This unit focuses on diversity in human populations, measurement, and data collection. Optional excursions are described for students who wish to study a topic in greater depth. An introduction describes…
ERIC Educational Resources Information Center
Bonar, John R., Ed.; Hathway, James A., Ed.
This is the student's text of one unit of the Intermediate Science Curriculum Study (ISCS) for level III students (grade 9). The chapters contain basic information about rockets, space, and principles of physics, as well as activities related to the subject and optional excursions. A section of introductory notes to the student discusses how the…
ERIC Educational Resources Information Center
Bonar, John R., Ed.; Hathway, James A., Ed.
This is the teacher's edition of one of the eight units of the Intermediate Science Curriculum Study (ISCS) for level III students (grade 9). This unit and its activities focuses on environmental pollution and hazards. Optional excursions are suggested for students who wish to study an area in greater depth. An introduction describes the problem…
ERIC Educational Resources Information Center
Boland, William Casey
2018-01-01
To date, there has been little analysis of MSI Title III and V grant-funded programs across all MSI categories. For researchers, practitioners, and policymakers, it is imperative to explore the contributions of MSIs as manifested in Title III and V grant-funded programs. The purpose of this study is to analyze MSI Title III and V programs based on…
Code of Federal Regulations, 2010 CFR
2010-10-01
... 46 Shipping 3 2010-10-01 2010-10-01 false Alternative Hull Examination (AHE) program options...-27 Alternative Hull Examination (AHE) program options: Divers or underwater remotely operated vehicle... operations; (2) Provide permanent hull markings, a temporary grid system of wires or cables spaced not more...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-12-21
... Change To Extend the Penny Pilot Program December 15, 2011. Pursuant to Section 19(b)(1) of the... a proposal for the BATS Options Market (``BATS Options'') to extend through June 30, 2012, the Penny Pilot Program (``Penny Pilot'') in options classes in certain issues (``Pilot Program'') previously...
45 CFR 1306.32 - Center-based program option.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 45 Public Welfare 4 2014-10-01 2014-10-01 false Center-based program option. 1306.32 Section 1306... annually for each child enrolled in a center-based program option. These visits must be initiated and... give individual attention to children entering and leaving the center. (d) Full day variation. (1) A...
45 CFR 1306.32 - Center-based program option.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 45 Public Welfare 4 2013-10-01 2013-10-01 false Center-based program option. 1306.32 Section 1306... annually for each child enrolled in a center-based program option. These visits must be initiated and... give individual attention to children entering and leaving the center. (d) Full day variation. (1) A...
45 CFR 1306.32 - Center-based program option.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 45 Public Welfare 4 2012-10-01 2012-10-01 false Center-based program option. 1306.32 Section 1306... annually for each child enrolled in a center-based program option. These visits must be initiated and... give individual attention to children entering and leaving the center. (d) Full day variation. (1) A...
Workstation table crashworthiness tests
DOT National Transportation Integrated Search
2013-12-31
This report describes results from the Option C component of a research program aimed at improving crashworthiness of passenger train workstation tables. Research conducted in the Base, Option A, and Option B components of the program was focused on ...
Grant Administration Manual for Title III Coordinators.
ERIC Educational Resources Information Center
Mathis, Emily Duncan; Ashmore, Frances W.
Guidelines for coordinators of programs under Title III of the Higher Education Act of 1965 are presented, based on a national survey of Title III program coordinators. The responsibilities of the coordinator and information on administering the Strengthening Developing Institutions Program (SDIP) grant are covered. The program can either be a…
The early management of Class III malocclusions using protraction headgear.
Macey-Dare, L V
2000-12-01
Class III malocclusions affect approximately 3% of Caucasians. Treatment options include; growth modification, dental camouflage and, once growth has ceased, orthognathic surgery. Originally, Class III malocclusions were thought to arise primarily from an overdevelopment of the mandible, but it is now known that maxillary retrusion contributes in up to 60% of cases. Maxillary retrusion is best treated with a combination of protraction headgear and rapid maxillary expansion, preferably before the age of 9 years. This article provides an overview of the management of skeletal Class III cases using protraction headgear with particular guidance for the general dental practitioner on when and how to treat.
Federal Register 2010, 2011, 2012, 2013, 2014
2011-10-06
... the Text of NYSE Arca Options Rule 6.96(b)(1)(B) to More Accurately Reflect the Regulatory Services... conditions), and to clarify the text of NYSE Arca Options Rule 6.96(b)(1)(B) to more accurately reflect the... Release''). See also Notice, 76 FR at 53515, n.5 and accompanying text. \\7\\ See Notice. III. Discussion...
17 CFR 240.15c3-1a - Options (Appendix A to 17 CFR 240.15c3-1).
Code of Federal Regulations, 2012 CFR
2012-04-01
... terms theoretical gains and losses shall mean the gain and loss in the value of individual option series... paragraph (a)(1)(iii) of this section). Theoretical gains and losses shall be calculated using a theoretical... models. Any such model shall calculate theoretical gains and losses as described in paragraph (a)(1)(i)(A...
Federal Register 2010, 2011, 2012, 2013, 2014
2010-12-03
... Change To Extend the Penny Pilot Program November 29, 2010. Pursuant to Section 19(b)(1) of the... Options'') to extend the Penny Pilot Program (``Penny Pilot'') in options classes in certain issues... BATS Options, including rules applicable to BATS Options' participation in the Penny Pilot, were...
How federalism shapes public health financing, policy, and program options.
Ogden, Lydia L
2012-01-01
In the United States, fiscal and functional federalism strongly shape public health policy and programs. Federalism has implications for public health practice: it molds financing and disbursement options, including funding formulas, which affect allocations and program goals, and shapes how funding decisions are operationalized in a political context. This article explores how American federalism, both fiscal and functional, structures public health funding, policy, and program options, investigating the effects of intergovernmental transfers on public health finance and programs.
ERIC Educational Resources Information Center
Bonar, John R., Ed.; Hathway, James A., Ed.
This is the student's edition of the Record Book for the unit "What's Up" of the Intermediate Science Curriculum Study (ISCS) for level III students (grade 9). Space is provided for answers to the questions from the student text as well as for the optional excursions and the self evaluation. An introductory note to the student explains…
ERIC Educational Resources Information Center
Bonar, John R., Ed.; Hathway, James A., Ed.
This is the teacher's edition of one of the eight units of the Intermediate Science Curriculum Study (ISCS) for level III students (grade 9). This unit focuses on hazards to the body from drug use. Activities are given that relate to the topic. Optional excursions are suggested for students who wish to study an area in greater depth. An…
ERIC Educational Resources Information Center
Dunne, Faith; And Others
Designed to last approximately 12 days, Unit III of the 4-unit life planning and career development curriculum for rural high school students focuses on skills application. Through experience simulation, students apply skills learned in Unit II to the information from Unit I; they project their future lives and simulate their responses to problems…
Kalua, Thokozani; Tippett Barr, Beth A; van Oosterhout, Joep J; Mbori-Ngacha, Dorothy; Schouten, Erik J; Gupta, Sundeep; Sande, Amakobe; Zomba, Gerald; Tweya, Hannock; Lungu, Edgar; Kajoka, Deborah; Tih, Pius; Jahn, Andreas
2017-05-01
The acceleration of prevention of mother-to-child transmission (PMTCT) activities, coupled with the rollout of 2010 World Health Organization (WHO) guidelines, led to important discussions and innovations at global and country levels. One paradigm-shifting innovation was Option B+ in Malawi. It was later included in WHO guidelines and eventually adopted by all 22 Global Plan priority countries. This article presents Malawi's experience with designing and implementing Option B+ and provides complementary narratives from Cameroon and Tanzania. Malawi's HIV program started in 2002, but by 2009, the PMTCT program was lagging far behind the antiretroviral therapy (ART) program because of numerous health system challenges. When WHO recommended Option A and Option B for PMTCT in 2010, it was clear that Malawi's HIV program would not be able to successfully implement either option without increasing existing barriers to PMTCT services and potentially decreasing women's access to care. Subsequent stakeholder discussions led to the development of Option B+. Operationalizing Option B+ required several critical considerations, including the complete integration of ART and PMTCT programs, systematic reduction of barriers to facilitate doubling the number of ART sites in less than a year, building consensus with stakeholders, and securing additional resources for the new program. During the planning and implementation process, several lessons were learned which are considerations for countries transitioning to "treat-all": Comprehensive change requires effective government leadership and coordination; national clinical guidelines must accommodate health system limitations; ART services and commodities should be decentralized within facilities; the general public should be well informed about major changes in the national HIV program; and patients should be educated on clinic processes to improve program monitoring.
Federal Register 2010, 2011, 2012, 2013, 2014
2012-12-31
... Change To Extend the Penny Pilot Program December 21, 2012. Pursuant to Section 19(b)(1) \\1\\ of the... Options'') to extend through June 30, 2013, the Penny Pilot Program (``Penny Pilot'') in options classes... Options, including rules applicable to BATS Options' participation in the Penny Pilot, were approved on...
Stowe, Ashley; Burger, Arnold
2016-05-10
A method for synthesizing I-III-VI.sub.2 compounds, including: melting a Group III element; adding a Group I element to the melted Group III element at a rate that allows the Group I and Group III elements to react thereby providing a single phase I-III compound; and adding a Group VI element to the single phase I-III compound under heat, with mixing, and/or via vapor transport. The Group III element is melted at a temperature of between about 200 degrees C. and about 700 degrees C. Preferably, the Group I element consists of a neutron absorber and the group III element consists of In or Ga. The Group VI element and the single phase I-III compound are heated to a temperature of between about 700 degrees C. and about 1000 degrees C. Preferably, the Group VI element consists of S, Se, or Te. Optionally, the method also includes doping with a Group IV element activator.
Shak, S
1999-08-01
The recombinant humanized anti-HER2 monoclonal antibody trastuzumab (Herceptin; Genentech, San Francisco, CA) was evaluated in human clinical trials for treatment of women with metastatic breast cancer who have tumors that overexpress HER2. The trastuzumab clinical program consisted of a series of phase I, phase II, and phase III clinical trials. Clinical experience with this novel biologic has been obtained in more than 1,000 women with HER2-overexpressing metastatic breast cancer. Two pivotal trials were performed to evaluate trastuzumab efficacy and safety: (1) trastuzumab in combination with chemotherapy as first-line therapy and (2) trastuzumab as a single agent in second- and third-line chemotherapy. Preliminary results of the pivotal clinical trials that have been presented at national meetings are summarized below. The data suggest that trastuzumab will be an important new treatment option for women with HER2-overexpressing metastatic breast cancer.
Federal Register 2010, 2011, 2012, 2013, 2014
2011-11-23
... Short Term Options Series Program November 17, 2011. I. Introduction On September 23, 2011, the...\\ and Rule 19b-4 thereunder,\\2\\ a proposed rule change to expand the Short Term Options Series Program... Exchange may select up to 25 option classes to participate in the STOS Program \\5\\ and list up to 30 Short...
ERIC Educational Resources Information Center
General Accounting Office, Washington, DC.
In this report GAO recommends that the Secretary of Education assess the advantages of consolidation loans for borrowers and the government in light of program costs and identify options for reducing federal costs. Options could include targeting the program to borrowers at risk of default and extending existing consolidation alternatives to more…
Federal Register 2010, 2011, 2012, 2013, 2014
2013-04-01
...\\ and Rule 19b-4 thereunder,\\2\\ notice is hereby given that on March 20, 2013, the Chicago Board Options... (the ``Commission'') the proposed rule change as described in Items I and II below, which Items have... rule change pursuant to Section 19(b)(3)(A)(iii) of the Act \\3\\ and Rule 19b-4(f)(6) thereunder.\\4\\ The...
Multi-mesh gear dynamics program evaluation and enhancements
NASA Technical Reports Server (NTRS)
Boyd, L. S.; Pike, J.
1985-01-01
A multiple mesh gear dynamics computer program was continually developed and modified during the last four years. The program can handle epicyclic gear systems as well as single mesh systems with internal, buttress, or helical tooth forms. The following modifications were added under the current funding: variable contact friction, planet cage and ring gear rim flexibility options, user friendly options, dynamic side bands, a speed survey option and the combining of the single and multiple mesh options into one general program. The modified program was evaluated by comparing calculated values to published test data and to test data taken on a Hamilton Standard turboprop reduction gear-box. In general, the correlation between the test data and the analytical data is good.
20 CFR 411.355 - What payment options does a State VR agency have?
Code of Federal Regulations, 2010 CFR
2010-04-01
... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false What payment options does a State VR agency... Ticket to Work Program § 411.355 What payment options does a State VR agency have? (a) The Ticket to Work program provides different payment options that are available to a State VR agency for providing services...
20 CFR 411.355 - What payment options does a State VR agency have?
Code of Federal Regulations, 2011 CFR
2011-04-01
... 20 Employees' Benefits 2 2011-04-01 2011-04-01 false What payment options does a State VR agency... Ticket to Work Program § 411.355 What payment options does a State VR agency have? (a) The Ticket to Work program provides different payment options that are available to a State VR agency for providing services...
20 CFR 411.355 - What payment options does a State VR agency have?
Code of Federal Regulations, 2012 CFR
2012-04-01
... 20 Employees' Benefits 2 2012-04-01 2012-04-01 false What payment options does a State VR agency... Ticket to Work Program § 411.355 What payment options does a State VR agency have? (a) The Ticket to Work program provides different payment options that are available to a State VR agency for providing services...
20 CFR 411.355 - What payment options does a State VR agency have?
Code of Federal Regulations, 2013 CFR
2013-04-01
... 20 Employees' Benefits 2 2013-04-01 2013-04-01 false What payment options does a State VR agency... Ticket to Work Program § 411.355 What payment options does a State VR agency have? (a) The Ticket to Work program provides different payment options that are available to a State VR agency for providing services...
20 CFR 411.355 - What payment options does a State VR agency have?
Code of Federal Regulations, 2014 CFR
2014-04-01
... 20 Employees' Benefits 2 2014-04-01 2014-04-01 false What payment options does a State VR agency... Ticket to Work Program § 411.355 What payment options does a State VR agency have? (a) The Ticket to Work program provides different payment options that are available to a State VR agency for providing services...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-12-17
... the Related non-STO), and $1 or greater where the strike price is between $75 and $150. The proposed... expand the Short Term Options Program with respect to non-index options. The text of the proposed rule... proposes to expand the Short Term Options (``STO'') Program for non-index options so that the Exchange may...
Future directions for postdoctoral training in cancer prevention: insights from a panel of experts.
Nelson, David E; Faupel-Badger, Jessica; Phillips, Siobhan; Belcher, Britni; Chang, Shine; Abrams, David B; Kramer, Barnett S; White, Mary C; O'Malley, Michael; Varanasi, Arti P; Fabian, Carol J; Wiest, Jonathan S; Colditz, Graham A; Hall, Kara; Shields, Peter G; Weitzel, Jeffrey N
2014-04-01
Cancer prevention postdoctoral fellowships have existed since the 1970s. The National Cancer Institute facilitated a meeting by a panel of experts in April 2013 to consider four important topics for future directions for cancer prevention postdoctoral training programs: (i) future research needs; (ii) underrepresented disciplines; (iii) curriculum; and (iv) career preparation. Panelists proffered several areas needing more research or emphasis, ranging from computational science to culture. Health care providers, along with persons from nontraditional disciplines in scientific training programs such as engineers and lawyers, were among those recognized as being underrepresented in training programs. Curriculum suggestions were that fellows receive training in topics such as leadership and human relations, in addition to learning the principles of epidemiology, cancer biologic mechanisms, and behavioral science. For career preparation, there was a clear recognition of the diversity of employment options available besides academic positions, and that program leaders should do more to help fellows identify and prepare for different career paths. The major topics and strategies covered at this meeting can help form the basis for cancer prevention training program leaders to consider modifications or new directions, and keep them updated with the changing scientific and employment climate for doctoral degree recipients and postdoctoral fellows.
Shandra Bos, Lakshmi; Shorey, Shefaly; Kulantaipian, Tamill Salvee; Sng, Jane S P; Tam, Wilson W S; Koh, Serena S L
2018-05-17
This pilot study aimed to (i) evaluate the effectiveness of a neonatal discharge program, (ii) identify relationships between parent and infant factors and parental efficacy and psychological distress, and (iii) identify ways to improve the neonatal discharge program. A quasiexperimental 1-group pretest/posttest design was used. Through consecutive sampling, 42 participants were recruited. Data were collected using self-report questionnaires. Self-administering instruments gathered data on parental efficacy and psychological distress as well as feedback and recommendations on the intervention. A significant increase in parental efficacy and a reduction in psychological distress were observed from pre- to postdischarge intervention. Significant relationships were found between parental efficacy and infants' gestational age, birth weight, gender, and participants' level of education, and a significant relationship was found between psychological distress and number of children from previous pregnancies. Moreover, an Internet-based program, in addition to the face-to-face teaching, was identified as a preferred option to aid in information retention. It is important to evaluate and enhance the neonatal discharge program to suit the parents of today while providing them with informational and emotional support. Future studies should explore parental coping and the long-term effects of their infant's birth and the intervention.
A two-dimensional graphing program for the Tektronix 4050-series graphics computers
Kipp, K.L.
1983-01-01
A refined, two-dimensional graph-plotting program was developed for use on Tektronix 4050-series graphics computers. Important features of this program include: any combination of logarithmic and linear axes, optional automatic scaling and numbering of the axes, multiple-curve plots, character or drawn symbol-point plotting, optional cartridge-tape data input and plot-format storage, optional spline fitting for smooth curves, and built-in data-editing options. The program is run while the Tektronix is not connected to any large auxiliary computer, although data from files on an auxiliary computer easily can be transferred to data-cartridge for later plotting. The user is led through the plot-construction process by a series of questions and requests for data input. Five example plots are presented to illustrate program capability and the sequence of program operation. (USGS)
A computer program for the design and analysis of low-speed airfoils, supplement
NASA Technical Reports Server (NTRS)
Eppler, R.; Somers, D. M.
1980-01-01
Three new options were incorporated into an existing computer program for the design and analysis of low speed airfoils. These options permit the analysis of airfoils having variable chord (variable geometry), a boundary layer displacement iteration, and the analysis of the effect of single roughness elements. All three options are described in detail and are included in the FORTRAN IV computer program.
Space Station Systems Analysis Study. Volume 1: Executive summary, part 1 and 2
NASA Technical Reports Server (NTRS)
1977-01-01
The elements of space station programs required to support an operational base theme, a space laboratory theme, and advanced missions relatable to public needs/national interests are defined. Missions satisfying the foregoing requirements are identified, program scenarios/options are established. System options are evaluated for a selected number of program options. Subsystem analysis and programmatic comparisons are performed for selected primary concepts.
Code of Federal Regulations, 2011 CFR
2011-04-01
... 24 Housing and Urban Development 1 2011-04-01 2011-04-01 false Homeownership programs (sections 235(i) and 235(j), Turnkey III and Indian housing mutual self-help programs). 8.29 Section 8.29...), Turnkey III and Indian housing mutual self-help programs). Any housing units newly constructed or...
Code of Federal Regulations, 2010 CFR
2010-04-01
... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Homeownership programs (sections 235(i) and 235(j), Turnkey III and Indian housing mutual self-help programs). 8.29 Section 8.29...), Turnkey III and Indian housing mutual self-help programs). Any housing units newly constructed or...
40 CFR 147.650 - State-administrative program-Class I, II, III, IV, and V wells.
Code of Federal Regulations, 2010 CFR
2010-07-01
... CONTROL PROGRAMS Idaho § 147.650 State-administrative program—Class I, II, III, IV, and V wells. The UIC program for Class I, II, III, IV, and V wells in the State of Idaho, other than those on Indian lands, is the program administered by the Idaho Department of Water Resources, approved by EPA pursuant to...
NASA Technical Reports Server (NTRS)
Ortiz, James N.; Scott,Kelly; Smith, Harold
2004-01-01
The assembly and operation of the ISS has generated significant challenges that have ultimately impacted resources available to the program's primary mission: research. To address this, program personnel routinely perform trade-off studies on alternative options to enhance research. The approach, content level of analysis and resulting outputs of these studies vary due to many factors, however, complicating the Program Manager's job of selecting the best option. To address this, the program requested a framework be developed to evaluate multiple research-enhancing options in a thorough, disciplined and repeatable manner, and to identify the best option on the basis of cost, benefit and risk. The resulting framework consisted of a systematic methodology and a decision-support toolset. The framework provides quantifiable and repeatable means for ranking research-enhancing options for the complex and multiple-constraint domain of the space research laboratory. This paper describes the development, verification and validation of this framework and provides observations on its operational use.
Saturveithan, C; Premganesh, G; Fakhrizzaki, S; Mahathir, M; Karuna, K; Rauf, K; William, H; Akmal, H; Sivapathasundaram, N; Jaspreet, K
2016-07-01
Introduction: Intra-articular hyaluronic acid (HA) is widely utilized in the treatment of knee osteoarthritis whereas platelet rich plasma (PRP) enhances the regeneration of articular cartilage. This study analyses the efficacy of HA and PRP in grade III and IV knee osteoarthritis. Methodology: This is a cross sectional study with retrospective review of 64 patients (101 knees) which includes 56 knees injected with HA+ PRP, and 45 knees with HA only. Results: During the post six months International Knee Documentation Committee (IKDC) evaluation, HA+PRP group showed marked improvement of 24.33 compared to 12.15 in HA group. Decrement in visual analogue score (VAS) in HA+PRP was 1.9 compared to 0.8 in HA group. Conclusion: We propose intra-articular HA and PRP injections as an optional treatment modality in Grade III and IV knee osteoarthritis in terms of functional outcome and pain control for up to six months when arthroplasty is not an option.
Premganesh, G; Fakhrizzaki, S; Mahathir, M; Karuna, K; Rauf, K; William, H; Akmal, H; Sivapathasundaram, N; Jaspreet, K
2016-01-01
Introduction: Intra-articular hyaluronic acid (HA) is widely utilized in the treatment of knee osteoarthritis whereas platelet rich plasma (PRP) enhances the regeneration of articular cartilage. This study analyses the efficacy of HA and PRP in grade III and IV knee osteoarthritis. Methodology: This is a cross sectional study with retrospective review of 64 patients (101 knees) which includes 56 knees injected with HA+ PRP, and 45 knees with HA only. Results: During the post six months International Knee Documentation Committee (IKDC) evaluation, HA+PRP group showed marked improvement of 24.33 compared to 12.15 in HA group. Decrement in visual analogue score (VAS) in HA+PRP was 1.9 compared to 0.8 in HA group. Conclusion: We propose intra-articular HA and PRP injections as an optional treatment modality in Grade III and IV knee osteoarthritis in terms of functional outcome and pain control for up to six months when arthroplasty is not an option. PMID:28435559
Federal Register 2010, 2011, 2012, 2013, 2014
2013-11-01
... DEPARTMENT OF EDUCATION Implementation of Title I/II Program Initiatives; Extension of Public Comment Period; Correction AGENCY: Department of Education. ACTION: Correction notice. SUMMARY: On October... Title I/II Program Initiatives,'' Docket ID ED- 2013-ICCD-0090. The comment period for this information...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-07-11
...; Comment Request; Implementation of Title I/II Program Initiatives AGENCY: Institute of Educational... note that written comments received in response to this notice will be considered public records. Title of Collection: Implementation of Title I/II Program Initiatives. OMB Control Number: 1850-New. Type...
Unified Program Design: Organizing Existing Programming Models, Delivery Options, and Curriculum
ERIC Educational Resources Information Center
Rubenstein, Lisa DaVia; Ridgley, Lisa M.
2017-01-01
A persistent problem in the field of gifted education has been the lack of categorization and delineation of gifted programming options. To address this issue, we propose Unified Program Design as a structural framework for gifted program models. This framework defines gifted programs as the combination of delivery methods and curriculum models.…
26 CFR 1.752-1 - Treatment of partnership liabilities.
Code of Federal Regulations, 2010 CFR
2010-04-01
..., obligations under a short sale, and obligations under derivative financial instruments such as options, forward contracts, futures contracts, and swaps. (iii) Other liabilities. For obligations that are not § 1...
Code of Federal Regulations, 2014 CFR
2014-01-01
... chapter. (iii) Bylaw provisions that adopt the language of the model or optional bylaws in OTS's... body or bodies of law selected for its corporate governance procedures, and shall file a copy of such...
Code of Federal Regulations, 2012 CFR
2012-01-01
... chapter. (iii) Bylaw provisions that adopt the language of the model or optional bylaws in OTS's... body or bodies of law selected for its corporate governance procedures, and shall file a copy of such...
Code of Federal Regulations, 2013 CFR
2013-01-01
... chapter. (iii) Bylaw provisions that adopt the language of the model or optional bylaws in OTS's... body or bodies of law selected for its corporate governance procedures, and shall file a copy of such...
2015-07-31
vicinity of the enzyme , searching for the active site; (iii) find the active site and position the substrate at it, triggering the catalysis . As the...visualization options. The Lysozyme example is used to introduce the concepts of how enzymes work, and use a view option to visualize the surface of the... enzyme , its active site and its substrate. It is also in this example that we introduce the Foldit Biology notion of a ‘protein state’. Each protein
Federal Register 2010, 2011, 2012, 2013, 2014
2012-11-15
... Available Under the Short Term Option Series Program (``STOS Program''), To Allow for the Exchange To Delist... Program Under Limited Circumstances November 8, 2012. I. Introduction On September 6, 2012, NYSE Arca, Inc...'') to make certain modifications to the Exchange's Short Term Option Series Program (``STOS Program...
ERIC Educational Resources Information Center
Elliott, Norman, Comp.
An analysis of the development of diverse educational programs based on a common curriculum core is the purpose of this paper. After an overview of the major kinds of option/choice programs, a study of educational options in Utah and the United States is described. Three research methodologies were used to collect data: a statewide survey on…
ERIC Educational Resources Information Center
Gauchat, Tiffanie A.
2010-01-01
The purpose of this study was to determine the effect of a career, academic, personal, and social high school transition program option on 9th-grade students' achievement, behavior, and engagement. Students in the career, academic, personal, and social group (n = 30) and the comparison academic/elective course option programs group (n = 30)…
ERIC Educational Resources Information Center
Puerto Rico Univ., San Juan. School of Dentistry.
The Dental Auxiliary Department of the University of Puerto Rico designed a career option dental auxiliary training program which is a step ladder program with three exit points over a period of two academic years. The first option is a six-month track to train a traditional chairside dental auxiliary. The second option is a nine-month track to…
Shah, Saurin R; Keshri, Amit; Patadia, Simple; Sahu, Rabi Narayan; Srivastava, Arun Kumar; Behari, Sanjay
2015-10-01
To study outcomes with endoscopic-assisted midfacial degloving for Fisch stage III nasopharyngeal angiofibroma and propose a new staging system. Retrospective study of patients with Fisch stage III juvenile nasopharyngeal angiofibroma (JNA) including preoperative angiography, intraoperative blood loss and residue/recurrence following surgery. Tertiary care superspecialty referral center. Fifteen consecutive patients with Fisch stage III JNA undergoing operations over a period of 18 months. Preoperative angiography details, intraoperative blood loss, residue/recurrence, complications of surgery. Transarterial embolization with particulate agents followed by endoscopic-assisted midfacial degloving provides excellent outcomes with Fisch stage III JNAs. The modified Fisch staging system proposed would allow better preoperative evaluation and comparison of outcomes with different treatment options for stage III JNAs. Copyright © 2015 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved.
Code of Federal Regulations, 2010 CFR
2010-10-01
... result of economic price adjustment, (ii) termination notices, and (iii) purchase order modifications as... Optional Form 336 (OF 336), Continuation Sheet, or a blank sheet of paper, may be used as a continuation...
7 CFR 1468.4 - Establishing Conservation Farm Option (CFO) pilot project areas.
Code of Federal Regulations, 2011 CFR
2011-01-01
...) Conservation of soil, water, and related natural resources, (ii) Water quality protection or improvement, (iii... that can be geographically described and has specific environmental sensitivities or significant soil...
48 CFR 570.105-2 - Two-phase design-build selection procedures.
Code of Federal Regulations, 2010 CFR
2010-10-01
... lease construction projects with options to purchase the real property leased. Use the procedures in.... (iii) The capability and experience of potential contractors. (iv) The suitability of the project for...
[Usher syndrome: clinical features, diagnostic options, and therapeutic prospects].
Seeliger, M W; Fischer, M D; Pfister, M
2009-06-01
Usher syndrome denotes a clinically and genetically heterogeneous combination of retinitis pigmentosa and sensorineural deafness. The division into subtypes I, II, and III is based on the degree of hearing loss: Type I is characterized by deafness from birth together with ataxia and retarded motor development, type II by a stationary deafness of a moderate degree, and type III by a progressive deafness with adult onset. In Germany, Usher syndrome currently bears particular relevance because in January 2009 a new compulsory screening of auditory function in newborn infants was introduced. Consequently, it can be expected that a higher number of patients with Usher syndrome will be identified in early childhood and referred to ophthalmologists. The focus of this work is to introduce the typical clinical picture of Usher syndrome, summarize diagnostic options, and give an overview of therapeutic strategies.
Life prediction and constitutive models for engine hot section anisotropic materials program
NASA Technical Reports Server (NTRS)
Nissley, D. M.; Meyer, T. G.
1992-01-01
This report presents the results from a 35 month period of a program designed to develop generic constitutive and life prediction approaches and models for nickel-based single crystal gas turbine airfoils. The program is composed of a base program and an optional program. The base program addresses the high temperature coated single crystal regime above the airfoil root platform. The optional program investigates the low temperature uncoated single crystal regime below the airfoil root platform including the notched conditions of the airfoil attachment. Both base and option programs involve experimental and analytical efforts. Results from uniaxial constitutive and fatigue life experiments of coated and uncoated PWA 1480 single crystal material form the basis for the analytical modeling effort. Four single crystal primary orientations were used in the experiments: (001), (011), (111), and (213). Specific secondary orientations were also selected for the notched experiments in the optional program. Constitutive models for an overlay coating and PWA 1480 single crystal material were developed based on isothermal hysteresis loop data and verified using thermomechanical (TMF) hysteresis loop data. A fatigue life approach and life models were selected for TMF crack initiation of coated PWA 1480. An initial life model used to correlate smooth and notched fatigue data obtained in the option program shows promise. Computer software incorporating the overlay coating and PWA 1480 constitutive models was developed.
An Option in Applied Microbiology.
ERIC Educational Resources Information Center
Lee, William E., III
1988-01-01
Describes a program option for undergraduate chemical engineering students interested in biotechnology. Discusses how this program is deployed at the University of Southern Florida. Lists courses which apply to this program. Discusses the goals of teaching applied microbiology to engineering majors. (CW)
Molena, Daniela; Mungo, Benedetto; Stem, Miloslawa; Feinberg, Richard L; Lidor, Anne O
2014-08-01
The development of minimally invasive operative techniques and improvement in postoperative care has made surgery a viable option to a greater number of elderly patients. Our objective was to evaluate the outcomes of laparoscopic and open foregut operation in relation to the patient age. Patients who underwent gastric fundoplication, paraesophageal hernia repair, and Heller myotomy were identified via the National Surgical Quality Improvement Program (NSQIP) database (2005-2011). Patient characteristics and outcomes were compared between five age groups (group I: ≤65 years, II: 65-69 years; III: 70-74 years; IV: 75-79 years; and V: ≥80 years). Multivariable logistic regression analysis was used to predict the impact of age and operative approach on the studied outcomes. A total of 19,388 patients were identified. Advanced age was associated with increased rate of 30-day mortality, overall morbidity, serious morbidity, and extended length of stay, regardless of the operative approach. After we adjusted for other variables, advanced age was associated with increased odds of 30-day mortality compared with patients <65 years (III: odds ratio 2.70, 95% confidence interval 1.34-5.44, P = .01; IV: 2.80, 1.35-5.81, P = .01; V: 6.12, 3.41-10.99, P < .001). Surgery for benign foregut disease in elderly patients carries a burden of mortality and morbidity that needs to be acknowledged. Copyright © 2014 Mosby, Inc. All rights reserved.
Federal Register 2010, 2011, 2012, 2013, 2014
2012-11-15
... Available Under the Short Term Option Series Program (``STOS Program''), To Allow for the Exchange To Delist... Program Under Limited Circumstances November 8, 2012. I. Introduction On September 6, 2012, NYSE MKT LLC... make certain modifications to the Exchange's Short Term Option Series Program (``STOS Program''). The...
NASA Astrophysics Data System (ADS)
Stoitsov, M. V.; Schunck, N.; Kortelainen, M.; Michel, N.; Nam, H.; Olsen, E.; Sarich, J.; Wild, S.
2013-06-01
We describe the new version 2.00d of the code HFBTHO that solves the nuclear Skyrme-Hartree-Fock (HF) or Skyrme-Hartree-Fock-Bogoliubov (HFB) problem by using the cylindrical transformed deformed harmonic oscillator basis. In the new version, we have implemented the following features: (i) the modified Broyden method for non-linear problems, (ii) optional breaking of reflection symmetry, (iii) calculation of axial multipole moments, (iv) finite temperature formalism for the HFB method, (v) linear constraint method based on the approximation of the Random Phase Approximation (RPA) matrix for multi-constraint calculations, (vi) blocking of quasi-particles in the Equal Filling Approximation (EFA), (vii) framework for generalized energy density with arbitrary density-dependences, and (viii) shared memory parallelism via OpenMP pragmas. Program summaryProgram title: HFBTHO v2.00d Catalog identifier: ADUI_v2_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/ADUI_v2_0.html Program obtainable from: CPC Program Library, Queen's University, Belfast, N. Ireland Licensing provisions: GNU General Public License version 3 No. of lines in distributed program, including test data, etc.: 167228 No. of bytes in distributed program, including test data, etc.: 2672156 Distribution format: tar.gz Programming language: FORTRAN-95. Computer: Intel Pentium-III, Intel Xeon, AMD-Athlon, AMD-Opteron, Cray XT5, Cray XE6. Operating system: UNIX, LINUX, WindowsXP. RAM: 200 Mwords Word size: 8 bits Classification: 17.22. Does the new version supercede the previous version?: Yes Catalog identifier of previous version: ADUI_v1_0 Journal reference of previous version: Comput. Phys. Comm. 167 (2005) 43 Nature of problem: The solution of self-consistent mean-field equations for weakly-bound paired nuclei requires a correct description of the asymptotic properties of nuclear quasi-particle wave functions. In the present implementation, this is achieved by using the single-particle wave functions of the transformed harmonic oscillator, which allows for an accurate description of deformation effects and pairing correlations in nuclei arbitrarily close to the particle drip lines. Solution method: The program uses the axial Transformed Harmonic Oscillator (THO) single- particle basis to expand quasi-particle wave functions. It iteratively diagonalizes the Hartree-Fock-Bogoliubov Hamiltonian based on generalized Skyrme-like energy densities and zero-range pairing interactions until a self-consistent solution is found. A previous version of the program was presented in: M.V. Stoitsov, J. Dobaczewski, W. Nazarewicz, P. Ring, Comput. Phys. Commun. 167 (2005) 43-63. Reasons for new version: Version 2.00d of HFBTHO provides a number of new options such as the optional breaking of reflection symmetry, the calculation of axial multipole moments, the finite temperature formalism for the HFB method, optimized multi-constraint calculations, the treatment of odd-even and odd-odd nuclei in the blocking approximation, and the framework for generalized energy density with arbitrary density-dependences. It is also the first version of HFBTHO to contain threading capabilities. Summary of revisions: The modified Broyden method has been implemented, Optional breaking of reflection symmetry has been implemented, The calculation of all axial multipole moments up to λ=8 has been implemented, The finite temperature formalism for the HFB method has been implemented, The linear constraint method based on the approximation of the Random Phase Approximation (RPA) matrix for multi-constraint calculations has been implemented, The blocking of quasi-particles in the Equal Filling Approximation (EFA) has been implemented, The framework for generalized energy density functionals with arbitrary density-dependence has been implemented, Shared memory parallelism via OpenMP pragmas has been implemented. Restrictions: Axial- and time-reversal symmetries are assumed. Unusual features: The user must have access to the LAPACK subroutines DSYEVD, DSYTRF and DSYTRI, and their dependences, which compute eigenvalues and eigenfunctions of real symmetric matrices, the LAPACK subroutines DGETRI and DGETRF, which invert arbitrary real matrices, and the BLAS routines DCOPY, DSCAL, DGEMM and DGEMV for double-precision linear algebra (or provide another set of subroutines that can perform such tasks). The BLAS and LAPACK subroutines can be obtained from the Netlib Repository at the University of Tennessee, Knoxville: http://netlib2.cs.utk.edu/. Running time: Highly variable, as it depends on the nucleus, size of the basis, requested accuracy, requested configuration, compiler and libraries, and hardware architecture. An order of magnitude would be a few seconds for ground-state configurations in small bases N≈8-12, to a few minutes in very deformed configuration of a heavy nucleus with a large basis N>20.
33 CFR 105.257 - Security measures for newly-hired employees.
Code of Federal Regulations, 2011 CFR
2011-07-01
... or the FSO enters the following information on the new hire into the Coast Guard's Homeport website...; (iii) Social security number (optional); (iv) Employer name and 24 hour contact information; and (v...
33 CFR 105.257 - Security measures for newly-hired employees.
Code of Federal Regulations, 2012 CFR
2012-07-01
... or the FSO enters the following information on the new hire into the Coast Guard's Homeport website...; (iii) Social security number (optional); (iv) Employer name and 24 hour contact information; and (v...
33 CFR 105.257 - Security measures for newly-hired employees.
Code of Federal Regulations, 2010 CFR
2010-07-01
... or the FSO enters the following information on the new hire into the Coast Guard's Homeport website...; (iii) Social security number (optional); (iv) Employer name and 24 hour contact information; and (v...
33 CFR 105.257 - Security measures for newly-hired employees.
Code of Federal Regulations, 2014 CFR
2014-07-01
... or the FSO enters the following information on the new hire into the Coast Guard's Homeport website...; (iii) Social security number (optional); (iv) Employer name and 24 hour contact information; and (v...
33 CFR 105.257 - Security measures for newly-hired employees.
Code of Federal Regulations, 2013 CFR
2013-07-01
... or the VSO enters the following information on the new hire into the Coast Guard's Homeport website...; (iii) Social security number (optional); (iv) Employer name and 24 hour contact information; and (v...
NATIONAL FRAMEWORK FOR THE SUSTAINABILITY OF HEALTH KNOWLEDGE TRANSLATION INITIATIVES IN UGANDA.
Basaza, Robert; Kinegyere, Alison; Mutatina, Boniface; Sewankambo, Nelson
2018-01-01
The aim of this study was to provide evidence about the design and implementation of policies for advancing the sustainability of knowledge translation (KT) initiatives and policies in Uganda's health system. We searched for and reviewed evidence about KT sustainability issues in Uganda, the impacts of options, barriers to implementing these options, and implementation strategies to address such barriers. In instances where the systematic reviews provided limited evidence, these were supplemented with relevant primary studies. Documents such as the government reports and unpublished literature were also included in the search. Key informant interviews and a policy dialogue were conducted, and an expert working group guided the study. The KT sustainability issues identified were: the absence of a specific unit within the health sector to coordinate and synthesize research; health worker not familiar with KT activities and not often used. Furthermore, Uganda lacks a mechanism to sustain its current national health frameworks or platforms, and does not have a system to ensure the sustained coordination of existing national health KT platforms. The policy options proposed include: (i) the identification of a KT champion; (ii) the establishment of an operational KT framework; (iii) KT capacity building for researchers and research users, as well as policy and decision makers. The sustainability of KT will be influenced by the prevailing context and concerns within healthcare both in Uganda and internationally. Furthermore, the availability of resources for KT advocacy, communication, and program design will impact on the sustainability of Uganda's KT activities.
Federal Register 2010, 2011, 2012, 2013, 2014
2012-09-05
.... Introduction On May 21, 2012, the International Securities Exchange, LLC (``ISE'' or ``Exchange'') filed with... its Short Term Option Series Program (``STOS Program'') to permit, during the expiration week of an... open for trading Short Term Option Series at $0.50 strike price intervals for option classes that trade...
Banerjee, Shyamashree; Gupta, Parth Sarthi Sen; Nayek, Arnab; Das, Sunit; Sur, Vishma Pratap; Seth, Pratyay; Islam, Rifat Nawaz Ul; Bandyopadhyay, Amal K
2015-01-01
Automated genome sequencing procedure is enriching the sequence database very fast. To achieve a balance between the entry of sequences in the database and their analyses, efficient software is required. In this end PHYSICO2, compare to earlier PHYSICO and other public domain tools, is most efficient in that it i] extracts physicochemical, window-dependent and homologousposition-based-substitution (PWS) properties including positional and BLOCK-specific diversity and conservation, ii] provides users with optional-flexibility in setting relevant input-parameters, iii] helps users to prepare BLOCK-FASTA-file by the use of Automated Block Preparation Tool of the program, iv] performs fast, accurate and user-friendly analyses and v] redirects itemized outputs in excel format along with detailed methodology. The program package contains documentation describing application of methods. Overall the program acts as efficient PWS-analyzer and finds application in sequence-bioinformatics. PHYSICO2: is freely available at http://sourceforge.net/projects/physico2/ along with its documentation at https://sourceforge.net/projects/physico2/files/Documentation.pdf/download for all users.
Banerjee, Shyamashree; Gupta, Parth Sarthi Sen; Nayek, Arnab; Das, Sunit; Sur, Vishma Pratap; Seth, Pratyay; Islam, Rifat Nawaz Ul; Bandyopadhyay, Amal K
2015-01-01
Automated genome sequencing procedure is enriching the sequence database very fast. To achieve a balance between the entry of sequences in the database and their analyses, efficient software is required. In this end PHYSICO2, compare to earlier PHYSICO and other public domain tools, is most efficient in that it i] extracts physicochemical, window-dependent and homologousposition-based-substitution (PWS) properties including positional and BLOCK-specific diversity and conservation, ii] provides users with optional-flexibility in setting relevant input-parameters, iii] helps users to prepare BLOCK-FASTA-file by the use of Automated Block Preparation Tool of the program, iv] performs fast, accurate and user-friendly analyses and v] redirects itemized outputs in excel format along with detailed methodology. The program package contains documentation describing application of methods. Overall the program acts as efficient PWS-analyzer and finds application in sequence-bioinformatics. Availability PHYSICO2: is freely available at http://sourceforge.net/projects/physico2/ along with its documentation at https://sourceforge.net/projects/physico2/files/Documentation.pdf/download for all users. PMID:26339154
Integrating an HTLV-III Screening Program into a Community Based Family Health Service Agency.
ERIC Educational Resources Information Center
Klausmeier, Walter W.; Henshaw, Beverly
Acquired Immune Deficiency Syndrome (AIDS) has become one of the most serious epidemic disease problems in recent years. In 1985 the Public Health Service recommended establishment of test sites where individuals might be tested for Human T Lymphotropic Virus III (HTLV-III) antibody. An HTLV-III antibody screening program was integrated into a…
40 CFR 52.1771 - Classification of regions.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 40 Protection of Environment 4 2013-07-01 2013-07-01 false Classification of regions. 52.1771 Section 52.1771 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS... III III III III Eastern Piedmont Intrastate I III III III III Northern Coastal Intrastate I III III...
40 CFR 52.1771 - Classification of regions.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 40 Protection of Environment 4 2014-07-01 2014-07-01 false Classification of regions. 52.1771 Section 52.1771 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS... III III III III Eastern Piedmont Intrastate I III III III III Northern Coastal Intrastate I III III...
40 CFR 52.1771 - Classification of regions.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 40 Protection of Environment 4 2011-07-01 2011-07-01 false Classification of regions. 52.1771 Section 52.1771 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS... III III III III Eastern Piedmont Intrastate I III III III III Northern Coastal Intrastate I III III...
40 CFR 52.1771 - Classification of regions.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 40 Protection of Environment 4 2010-07-01 2010-07-01 false Classification of regions. 52.1771 Section 52.1771 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS... III III III III Eastern Piedmont Intrastate I III III III III Northern Coastal Intrastate I III III...
40 CFR 52.1771 - Classification of regions.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 40 Protection of Environment 4 2012-07-01 2012-07-01 false Classification of regions. 52.1771 Section 52.1771 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS... III III III III Eastern Piedmont Intrastate I III III III III Northern Coastal Intrastate I III III...
Life prediction and constitutive models for engine hot section anisotropic materials program
NASA Technical Reports Server (NTRS)
Nissley, D. M.; Meyer, T. G.; Walker, K. P.
1992-01-01
This report presents a summary of results from a 7 year program designed to develop generic constitutive and life prediction approaches and models for nickel-based single crystal gas turbine airfoils. The program was composed of a base program and an optional program. The base program addressed the high temperature coated single crystal regime above the airfoil root platform. The optional program investigated the low temperature uncoated single crystal regime below the airfoil root platform including the notched conditions of the airfoil attachment. Both base and option programs involved experimental and analytical efforts. Results from uniaxial constitutive and fatigue life experiments of coated and uncoated PWA 1480 single crystal material formed the basis for the analytical modeling effort. Four single crystal primary orientations were used in the experiments: group of zone axes (001), group of zone axes (011), group of zone axes (111), and group of zone axes (213). Specific secondary orientations were also selected for the notched experiments in the optional program. Constitutive models for an overlay coating and PWA 1480 single crystal materials were developed based on isothermal hysteresis loop data and verified using thermomechanical (TMF) hysteresis loop data. A fatigue life approach and life models were developed for TMF crack initiation of coated PWA 1480. A life model was developed for smooth and notched fatigue in the option program. Finally, computer software incorporating the overlay coating and PWA 1480 constitutive and life models was developed.
26 CFR 1.401(a)-4 - Optional forms of benefit (before 1994).
Code of Federal Regulations, 2012 CFR
2012-04-01
... nondiscriminatory group of employees. (iii) Special rule for certain governmental or church plans. Plans described... income taxation under section 501(a), including plans subject to section 403(b)(12)(A)(i) (nonelective...
26 CFR 1.401(a)-4 - Optional forms of benefit (before 1994).
Code of Federal Regulations, 2014 CFR
2014-04-01
... nondiscriminatory group of employees. (iii) Special rule for certain governmental or church plans. Plans described... income taxation under section 501(a), including plans subject to section 403(b)(12)(A)(i) (nonelective...
26 CFR 1.401(a)-4 - Optional forms of benefit (before 1994).
Code of Federal Regulations, 2013 CFR
2013-04-01
... nondiscriminatory group of employees. (iii) Special rule for certain governmental or church plans. Plans described... income taxation under section 501(a), including plans subject to section 403(b)(12)(A)(i) (nonelective...
An Update on the Current Management of Perforated Diverticulitis.
Zoog, Evon; Giles, W Heath; Maxwell, Robert A
2017-12-01
The management of perforated diverticulitis is a challenging aspect of general surgery. The prevalence of colonic diverticular disease has increased over the last decade and will continue to increase as the baby boomers add to the elderly population. Improvements in diagnostic imaging modalities, efforts to maintain intestinal continuity, and percutaneous drainage procedures now result in several alternatives when selecting a management strategy for complicated presentations. Specifically, laparoscopic lavage and resection with primary anastomosis have emerged as options for treatment of Hinchey III and IV diverticulitis in place of diversion in the appropriately selected patient. Percutaneous drainage of Hinchey II diverticulitis in centers equipped with interventional radiology provides another minimally invasive adjunct. The objective of this paper is to provide an update on the current management of perforated diverticulitis, with a focus on the advantages and disadvantages of the surgical options for the treatment of Hinchey III and IV diverticulitis.
This booklet, ETV Program Case Studies: Demonstrating Program Outcomes, Volume III contains two case studies, addressing verified environmental technologies for decentalized wastewater treatment and converting animal waste to energy. Each case study contains a brief description ...
31 CFR 344.2 - What general provisions apply to SLGS securities?
Code of Federal Regulations, 2014 CFR
2014-07-01
..., 2005, it is impermissible: (i) To use the SLGS program to create a cost-free option; (ii) To purchase a... a cost-free option. In addition, this practice is prohibited under paragraph (f)(1)(i) of this... would result in the SLGS program being used to create a cost-free option. In addition, this practice is...
Federal Register 2010, 2011, 2012, 2013, 2014
2012-09-05
... Strike Price Intervals in the Short Term Options Program August 29, 2012. I. Introduction On July 2, 2012...-4 thereunder,\\2\\ a proposed rule change to indicate that the interval between strike prices on short term options series (``STOs'') listed in accordance with its Short Term Option Series Program (``STO...
ERIC Educational Resources Information Center
Old Coyote, Elnora A.; Chesarek, John Stephen
A description of the history and development of the University of Montana's American Indian education option in elementary teacher education is presented. Objectives and goals for the federally funded project are given, and the core personnel involved in the program are introduced. Budgeting procedures for the implementation of the option are…
A Review of Research Methods Used to Examine Employee Assistance Program Delivery Options.
ERIC Educational Resources Information Center
Csiernik, Rick
1995-01-01
This review of literature on Employee Assistance Programs (EAPs) focuses on EAP delivery options. More than half of the 48 studies reviewed used a case study approach. EAPs provided by on-staff professionals were the most frequently discussed delivery option, although this is not the most dominant form of EAP provision. (SLD)
Expansion of epicyclic gear dynamic analysis program
NASA Technical Reports Server (NTRS)
Boyd, Linda Smith; Pike, James A.
1987-01-01
The multiple mesh/single stage dynamics program is a gear tooth analysis program which determines detailed geometry, dynamic loads, stresses, and surface damage factors. The program can analyze a variety of both epicyclic and single mesh systems with spur or helical gear teeth including internal, external, and buttress tooth forms. The modifications refine the options for the flexible carrier and flexible ring gear rim and adds three options: a floating Sun gear option; a natural frequency option; and a finite element compliance formulation for helical gear teeth. The option for a floating Sun incorporates two additional degrees of freedom at the Sun center. The natural frequency option evaluates the frequencies of planetary, star, or differential systems as well as the effect of additional springs at the Sun center and those due to a flexible carrier and/or ring gear rim. The helical tooth pair finite element calculated compliance is obtained from an automated element breakup of the helical teeth and then is used with the basic gear dynamic solution and stress postprocessing routines. The flexible carrier or ring gear rim option for planetary and star spur gear systems allows the output torque per carrier and ring gear rim segment to vary based on the dynamic response of the entire system, while the total output torque remains constant.
Space Station Systems Analysis Study. Volume 2: Program options, book 1, parts 1 and 2
NASA Technical Reports Server (NTRS)
1977-01-01
Program options are defined and requirements are determined for integrating crew, mass, volume, and electrical power for a space construction base which incorporates the space shuttle external tanks. Orbits, stabilization, flight control hardware, as well as modules and aids for orbital assembly and servicing are considered. The effectiveness of various program options for life science and radio astronomy missions, for the solar terrestrial observatory, and for public service platforms is assessed. Technology development items are identified and costs are estimated.
A computer graphics program for general finite element analyses
NASA Technical Reports Server (NTRS)
Thornton, E. A.; Sawyer, L. M.
1978-01-01
Documentation for a computer graphics program for displays from general finite element analyses is presented. A general description of display options and detailed user instructions are given. Several plots made in structural, thermal and fluid finite element analyses are included to illustrate program options. Sample data files are given to illustrate use of the program.
ERIC Educational Resources Information Center
Idaho State Dept. of Education. Special Education Section.
This manual is designed to help Idaho school districts establish or improve programs for gifted and talented (G/T) high school students. It describes specific program options and administrative issues relating to gifted education. Chapter 1, "Starting and Administering a G/T High School Program," answers common questions about G/T high…
Di Monta, Gianluca; Caracò, Corrado; Simeone, Ester; Grimaldi, Antonio Maria; Marone, Ugo; Di Marzo, Massimiliano; Vanella, Vito; Festino, Lucia; Palla, Marco; Mori, Stefano; Mozzillo, Nicola; Ascierto, Paolo Antonio
2017-04-26
Extensive squamous cell carcinoma has few therapeutic options. In such cases, electrochemotherapy involving electroporation combined with antineoplastic drug appears to be a new potential option and may be considered as an alternative treatment. The aim of this retrospective single-center study was to evaluate electrochemotherapy efficacy in treatment of locally advanced stage III squamous cell carcinoma, in which surgical procedures would have entailed wide tissue sacrifice. Clinical features, treatment response, and adverse effects were evaluated in 22 patients treated with electrochemotherapy with intravenous injection of bleomycin for extensive stage III cutaneous squamous cell carcinoma. Treatment of cutaneous lesions were performed according to the European Standard Operating Procedures of Electrochemotherapy. Overall response to electrochemotherapy treatment was observed in 18 (81.8%) patients. Clinical response with necrosis of tumor mass was observed from the first session and lasted for all follow up period that ranged between 5 and 48 months with a median of 34 months. Overall the treatment was well tolerated with a very low complication rate. Electrochemotherapy represents a safe and effective therapeutic approach, associated with a good tolerability.
Space Storable Rocket Technology program (SSRT). Option 1 program
NASA Astrophysics Data System (ADS)
Chazen, Melvin L.; Mueller, Thomas; Rust, Thomas
1993-08-01
The Space Storable Rocket Technology (SSRT) Option 1 Program was initiated in October 1991 after completion of the Basic Program. The program was restructured in mid-July 1992 to incorporate a Rhenium Technology Task and reduce the scope of the LO2-N2H4 engine development. The program was also extended to late February 1993 to allow for the Rhenium Technology Task completion. The Option 1 Program was devoted to evaluation of two new injector elements, evaluation of two different methods of thermal protection of the injector, evaluation of high temperature material properties of rhenium and evaluation of methods of joining the rhenium thrust chamber to the columbium injector and nozzle extension. In addition, critical experiments were conducted (Funded by Option 2) to evaluate mechanisms to understand the effects of GO2 injection into the chamber, helium injection into the main LO2, effect of the splash plate and effect of decreasing the aspect ratio of the 120-slot (-13a) element. The performance and thermal models were used to further correlate the test results with analyses. The results of the work accomplished are summarized.
Space Storable Rocket Technology program (SSRT). Option 1 program
NASA Technical Reports Server (NTRS)
Chazen, Melvin L.; Mueller, Thomas; Rust, Thomas
1993-01-01
The Space Storable Rocket Technology (SSRT) Option 1 Program was initiated in October 1991 after completion of the Basic Program. The program was restructured in mid-July 1992 to incorporate a Rhenium Technology Task and reduce the scope of the LO2-N2H4 engine development. The program was also extended to late February 1993 to allow for the Rhenium Technology Task completion. The Option 1 Program was devoted to evaluation of two new injector elements, evaluation of two different methods of thermal protection of the injector, evaluation of high temperature material properties of rhenium and evaluation of methods of joining the rhenium thrust chamber to the columbium injector and nozzle extension. In addition, critical experiments were conducted (Funded by Option 2) to evaluate mechanisms to understand the effects of GO2 injection into the chamber, helium injection into the main LO2, effect of the splash plate and effect of decreasing the aspect ratio of the 120-slot (-13a) element. The performance and thermal models were used to further correlate the test results with analyses. The results of the work accomplished are summarized.
A Kramers-Moyal approach to the analysis of third-order noise with applications in option valuation.
Popescu, Dan M; Lipan, Ovidiu
2015-01-01
We propose the use of the Kramers-Moyal expansion in the analysis of third-order noise. In particular, we show how the approach can be applied in the theoretical study of option valuation. Despite Pawula's theorem, which states that a truncated model may exhibit poor statistical properties, we show that for a third-order Kramers-Moyal truncation model of an option's and its underlier's price, important properties emerge: (i) the option price can be written in a closed analytical form that involves the Airy function, (ii) the price is a positive function for positive skewness in the distribution, (iii) for negative skewness, the price becomes negative only for price values that are close to zero. Moreover, using third-order noise in option valuation reveals additional properties: (iv) the inconsistencies between two popular option pricing approaches (using a "delta-hedged" portfolio and using an option replicating portfolio) that are otherwise equivalent up to the second moment, (v) the ability to develop a measure R of how accurately an option can be replicated by a mixture of the underlying stocks and cash, (vi) further limitations of second-order models revealed by introducing third-order noise.
Federal Register 2010, 2011, 2012, 2013, 2014
2010-03-30
... schedule to execution charges for inbound ``Linkage Orders'' which only applied to the execution of linkage... in footnote (6) regarding the marketing fee; (iii) delete references to the old linkage in footnote...
Federal Register 2010, 2011, 2012, 2013, 2014
2010-07-09
... calculated index at about the time that the Short Term Option Series is opened. If the Exchange opens less... Securities Exchange, LLC To Expand and Permanently Establish Its Short Term Option Series Program July 2... proposes to amend its rules to regarding the Short Term Option Series Program. The text of the proposed...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-12-20
... Effectiveness of a Proposed Rule Relating to the Quarterly Option Series Program December 16, 2013. Pursuant to... the Quarterly Options Series (``QOS'') Program to eliminate the cap on the number of additional series... eliminate the cap on the number of additional series that may be listed per expiration month for each QOS in...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-12-09
... 3120 To Extend the Pilot Program That Eliminated the Position Limits for Options on SPDR S&P 500 ETF... extend the pilot program that eliminated the position limits for options on SPDR S&P 500 ETF (``SPY...- regulatory organizations (``SROs'') have adopted similar rules eliminating position limits on SPY and market...
45 CFR 308.3 - Optional program areas of review.
Code of Federal Regulations, 2013 CFR
2013-10-01
... SUPPORT ENFORCEMENT PROGRAM), ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN... experience, or job search. (c) A State may provide any of the optional information in paragraphs (a) and (b...
45 CFR 308.3 - Optional program areas of review.
Code of Federal Regulations, 2014 CFR
2014-10-01
... SUPPORT ENFORCEMENT PROGRAM), ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN... experience, or job search. (c) A State may provide any of the optional information in paragraphs (a) and (b...
45 CFR 308.3 - Optional program areas of review.
Code of Federal Regulations, 2011 CFR
2011-10-01
... SUPPORT ENFORCEMENT PROGRAM), ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN... experience, or job search. (c) A State may provide any of the optional information in paragraphs (a) and (b...
45 CFR 308.3 - Optional program areas of review.
Code of Federal Regulations, 2012 CFR
2012-10-01
... SUPPORT ENFORCEMENT PROGRAM), ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN... experience, or job search. (c) A State may provide any of the optional information in paragraphs (a) and (b...
Space Tug systems study (storable). Volume 3: Executive summary
NASA Technical Reports Server (NTRS)
1974-01-01
Space tug program options that consider key issues and mission requirements are assessed, component and subsystem candidates are evaluated, and tug configurations synthesized. Three tug program options are defined and evaluated.
45 CFR 1306.36 - Additional Head Start program option variations.
Code of Federal Regulations, 2010 CFR
2010-10-01
... HUMAN DEVELOPMENT SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES THE ADMINISTRATION FOR CHILDREN..., home-based, combination programs, and family child care options defined in this part, the Director of the Office of Head Start retains the right to fund alternative program variations to meet the unique...
Code of Federal Regulations, 2014 CFR
2014-04-01
... for homeownership assistance for disabled families. 982.642 Section 982.642 Housing and Urban... option: Pilot program for homeownership assistance for disabled families. (a) General. This section... Act of 2000. Under the pilot program, a PHA may provide homeownership assistance to a disabled family...
Code of Federal Regulations, 2011 CFR
2011-04-01
... for homeownership assistance for disabled families. 982.642 Section 982.642 Housing and Urban... option: Pilot program for homeownership assistance for disabled families. (a) General. This section... Act of 2000. Under the pilot program, a PHA may provide homeownership assistance to a disabled family...
Code of Federal Regulations, 2010 CFR
2010-04-01
... for homeownership assistance for disabled families. 982.642 Section 982.642 Housing and Urban... option: Pilot program for homeownership assistance for disabled families. (a) General. This section... Act of 2000. Under the pilot program, a PHA may provide homeownership assistance to a disabled family...
Code of Federal Regulations, 2012 CFR
2012-04-01
... for homeownership assistance for disabled families. 982.642 Section 982.642 Housing and Urban... option: Pilot program for homeownership assistance for disabled families. (a) General. This section... Act of 2000. Under the pilot program, a PHA may provide homeownership assistance to a disabled family...
Code of Federal Regulations, 2013 CFR
2013-04-01
... for homeownership assistance for disabled families. 982.642 Section 982.642 Housing and Urban... option: Pilot program for homeownership assistance for disabled families. (a) General. This section... Act of 2000. Under the pilot program, a PHA may provide homeownership assistance to a disabled family...
Education for Entrepreneurship in the Curriculum at University Level.
ERIC Educational Resources Information Center
Fleming, Patricia
1999-01-01
An integrated entrepreneurship education program at the University of Limerick, Ireland, promotes awareness of business ownership as a career option. Based on a process model of entrepreneurship, the program includes an entrepreneurship minor option and a required core module for all in the business studies program. (SK)
Computer program documentation: CYBER to Univac binary conversion user's guide
NASA Technical Reports Server (NTRS)
Martin, E. W.
1980-01-01
A user's guide for a computer program which will convert SINDA temperature history data from CDC (Cyber) binary format to UNIVAC 1100 binary format is presented. The various options available, the required input, the optional output, file assignments, and the restrictions of the program are discussed.
The Community Options Program: An Evaluation of Early Implementation Experience.
ERIC Educational Resources Information Center
Wisconsin State Dept. of Health and Social Services, Madison.
This document contains a preliminary report on the implementation of Wisconsin's Community Options Program (COP), a program designed both to divert persons from entering nursing homes and to deinstitutionalize current nursing home residents who can be effectively served by community-based alternatives. The introduction of this report provides a…
Expansion/Facemask Treatment of an Adult Class III Malocclusion.
Jackson, Gregory W; Kravitz, Neal D
2014-01-01
The orthodontic treatment of class III malocclusion with a maxillary deficiency is often treated with maxillary protraction with or without expansion. Skeletal and dental changes have been documented which have combined for the protraction of the maxilla and the correction of the class III malocclusion. Concerning the ideal time to treat a developing class III malocclusion, studies have reported that, although early treatment may be the most effective, face mask therapy can provide a viable option for older children as well. But what about young adults? Can the skeletal and dental changes seen in expansion/facemask therapy in children and adolescents be demonstrated in this age group as well, possibly eliminating the need for orthodontic dental camouflage treatment or orthognathic surgery? A case report is presented of an adult class III malocclusion with a Class III skeletal pattern and maxillary retrusion. Treatment was with nonextraction, comprehensive edgewise mechanics with slow maxillary expansion with a bonded expander and protraction facemask.
2013-01-01
Background Despite the widespread use of multiple-choice assessments in medical education assessment, current practice and published advice concerning the number of response options remains equivocal. This article describes an empirical study contrasting the quality of three 60 item multiple-choice test forms within the Royal Australian and New Zealand College of Obstetricians and Gynaecologists (RANZCOG) Fetal Surveillance Education Program (FSEP). The three forms are described below. Methods The first form featured four response options per item. The second form featured three response options, having removed the least functioning option from each item in the four-option counterpart. The third test form was constructed by retaining the best performing version of each item from the first two test forms. It contained both three and four option items. Results Psychometric and educational factors were taken into account in formulating an approach to test construction for the FSEP. The four-option test performed better than the three-option test overall, but some items were improved by the removal of options. The mixed-option test demonstrated better measurement properties than the fixed-option tests, and has become the preferred test format in the FSEP program. The criteria used were reliability, errors of measurement and fit to the item response model. Conclusions The position taken is that decisions about the number of response options be made at the item level, with plausible options being added to complete each item on both psychometric and educational grounds rather than complying with a uniform policy. The point is to construct the better performing item in providing the best psychometric and educational information. PMID:23453056
Zoanetti, Nathan; Beaves, Mark; Griffin, Patrick; Wallace, Euan M
2013-03-04
Despite the widespread use of multiple-choice assessments in medical education assessment, current practice and published advice concerning the number of response options remains equivocal. This article describes an empirical study contrasting the quality of three 60 item multiple-choice test forms within the Royal Australian and New Zealand College of Obstetricians and Gynaecologists (RANZCOG) Fetal Surveillance Education Program (FSEP). The three forms are described below. The first form featured four response options per item. The second form featured three response options, having removed the least functioning option from each item in the four-option counterpart. The third test form was constructed by retaining the best performing version of each item from the first two test forms. It contained both three and four option items. Psychometric and educational factors were taken into account in formulating an approach to test construction for the FSEP. The four-option test performed better than the three-option test overall, but some items were improved by the removal of options. The mixed-option test demonstrated better measurement properties than the fixed-option tests, and has become the preferred test format in the FSEP program. The criteria used were reliability, errors of measurement and fit to the item response model. The position taken is that decisions about the number of response options be made at the item level, with plausible options being added to complete each item on both psychometric and educational grounds rather than complying with a uniform policy. The point is to construct the better performing item in providing the best psychometric and educational information.
Atezolizumab: A Review in Previously Treated Advanced Non-Small Cell Lung Cancer.
Blair, Hannah A
2018-05-21
Atezolizumab (TECENTRIQ™), an immune checkpoint inhibitor, is an immunoglobulin G1 monoclonal antibody that binds to programmed death ligand 1 (PD-L1) and blocks its interactions with programmed death 1 and B7.1 receptors. Atezolizumab is approved as monotherapy in several countries worldwide for the treatment of patients with advanced non-small cell lung cancer (NSCLC) who have previously received chemotherapy. Approval was based on its clinical benefit in this setting in the phase II POPLAR and phase III OAK trials. In these studies, atezolizumab significantly prolonged overall survival (OS) relative to docetaxel, regardless of PD-L1 status. Increasing PD-L1 expression was associated with OS improvements. Atezolizumab also demonstrated efficacy in the phase II FIR and BIRCH trials, as assessed by objective response rates (ORRs) in patients with tumours expressing PD-L1. Higher ORRs were seen in patients with high PD-L1 expression. Atezolizumab had an acceptable, manageable tolerability profile, with a low incidence of immune-related adverse events. Therefore, atezolizumab is a valuable treatment option for patients with advanced NSCLC that has progressed during or after chemotherapy.
Routine Treatment of Cervical Cytological Cell Changes
Huber, J.; Pötsch, B.; Gantschacher, M.; Templ, M.
2016-01-01
Introduction: Diagnosis and treatment of vaginal and cervical cytological cell changes are described in European and national guidelines. The aim of this data collection was to evaluate the remission rates of PAP III and PAP III D cytological findings in patients over a period of 3–4 months. Method: The current state of affairs in managing suspicious and cytological findings (PAP III, and III D) in gynecological practice was assessed in the context of a data collection survey. An evaluation over a period of 24 months was conducted on preventative measures, the occurrence and changes to normal/suspect/pathological findings and therapy management (for suspicious or pathological findings). Results: 307 female patients were included in the analysis. At the time of the survey 186 patients (60.6 %) had PAP III and 119 (38.8 %) had PAP III D findings. The spontaneous remission rate of untreated PAP III patients was 6 % and that of untreated PAP III D patients was 11 %. The remission rates of patients treated with a vaginal gel were 77 % for PAP III and 71 % for PAP III D. Conclusion: A new treatment option was used in gynecological practice on patients with PAP III and PAP III D findings between confirmation and the next follow-up with excellent success. PMID:27761030
ERIC Educational Resources Information Center
Brodersen, R. Marc; Melluzzo, Daniel
2017-01-01
This report summarizes the methodology, measures, and findings of research on the influence on student achievement outcomes of K-12 online and blended face-to-face and online learning programs that offer differentiated learning options. The report also describes the characteristics of the learning programs. Most of the examined programs used…
Federal Register 2010, 2011, 2012, 2013, 2014
2010-01-11
... OMX PHLX, Inc. To Amend the $1 Strike Program To Allow Low-Strike LEAPS January 4, 2010. Pursuant to... 1012 (Series of Options Open for Trading) to expand the Exchange's $1 Strike Price Program (``Program'' or ``$1 Strike Program'') \\3\\ to allow listing long-term option series (``LEAPS'') \\4\\ in $1 strike...
COMOC 2: Two-dimensional aerodynamics sequence, computer program user's guide
NASA Technical Reports Server (NTRS)
Manhardt, P. D.; Orzechowski, J. A.; Baker, A. J.
1977-01-01
The COMOC finite element fluid mechanics computer program system is applicable to diverse problem classes. The two dimensional aerodynamics sequence was established for solution of the potential and/or viscous and turbulent flowfields associated with subsonic flight of elementary two dimensional isolated airfoils. The sequence is constituted of three specific flowfield options in COMOC for two dimensional flows. These include the potential flow option, the boundary layer option, and the parabolic Navier-Stokes option. By sequencing through these options, it is possible to computationally construct a weak-interaction model of the aerodynamic flowfield. This report is the user's guide to operation of COMOC for the aerodynamics sequence.
ST-analyzer: a web-based user interface for simulation trajectory analysis.
Jeong, Jong Cheol; Jo, Sunhwan; Wu, Emilia L; Qi, Yifei; Monje-Galvan, Viviana; Yeom, Min Sun; Gorenstein, Lev; Chen, Feng; Klauda, Jeffery B; Im, Wonpil
2014-05-05
Molecular dynamics (MD) simulation has become one of the key tools to obtain deeper insights into biological systems using various levels of descriptions such as all-atom, united-atom, and coarse-grained models. Recent advances in computing resources and MD programs have significantly accelerated the simulation time and thus increased the amount of trajectory data. Although many laboratories routinely perform MD simulations, analyzing MD trajectories is still time consuming and often a difficult task. ST-analyzer, http://im.bioinformatics.ku.edu/st-analyzer, is a standalone graphical user interface (GUI) toolset to perform various trajectory analyses. ST-analyzer has several outstanding features compared to other existing analysis tools: (i) handling various formats of trajectory files from MD programs, such as CHARMM, NAMD, GROMACS, and Amber, (ii) intuitive web-based GUI environment--minimizing administrative load and reducing burdens on the user from adapting new software environments, (iii) platform independent design--working with any existing operating system, (iv) easy integration into job queuing systems--providing options of batch processing either on the cluster or in an interactive mode, and (v) providing independence between foreground GUI and background modules--making it easier to add personal modules or to recycle/integrate pre-existing scripts utilizing other analysis tools. The current ST-analyzer contains nine main analysis modules that together contain 18 options, including density profile, lipid deuterium order parameters, surface area per lipid, and membrane hydrophobic thickness. This article introduces ST-analyzer with its design, implementation, and features, and also illustrates practical analysis of lipid bilayer simulations. Copyright © 2014 Wiley Periodicals, Inc.
Rural Energy Options Analysis Training Development and Implementation at NREL
DOE Office of Scientific and Technical Information (OSTI.GOV)
Gilman, P.
2005-01-01
NREL has developed a rural energy options analysis training program for rural energy decision makers that provides knowledge, skills and tools for the evaluation of technologies, including renewables, for rural energy applications. Through the Department of Energy (DOE) Solar Energy Technologies Program (SETP), NREL has refined materials for the program and developed a module that offers hands-on training in the preparation of data for options analysis using HOMER, NREL's micropower optimization model. NREL has used the materials for training in Brazil, the Maldives, Mexico, and Sri Lanka.
Understanding your capital options.
Payne, Christopher T
2012-05-01
When planning capital expenditures, hospitals and health systems should understand the following financing considerations: Traditional fixed-rate tax-exempt bonds; Variable-rate financing alternatives; Basel III Accord requirements; Direct tax-exempt bank loans; Total return swaps Taxable financings; Interest-rate swaps and collateral requirements
Smart Columbus : Systems Engineering Management Plan (SEMP) for Smart Columbus Demonstration Program
DOT National Transportation Integrated Search
2018-01-16
The Smart City Demonstration Program is intended to improve access through expanded mobility options in major job centers, enhance visitor experience by better connecting visitors to transportation options, stimulate regional economic prosperity and ...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-04-08
... amend Phlx Rule 1079 (FLEX Index, Equity and Currency Options) to extend a pilot program that eliminates...\\ \\3\\ In addition to FLEX Options, FLEX currency options are also traded on the Exchange. These flexible index, equity, and currency options provide investors the ability to customize basic option...
Federal Register 2010, 2011, 2012, 2013, 2014
2012-04-06
... Index, Equity and Currency Options) to extend a pilot program that eliminates minimum value sizes for... FLEX Options, FLEX currency options are also traded on the Exchange. These flexible index, equity, and currency options provide investors the ability to customize basic option features including size...
Federal Register 2010, 2011, 2012, 2013, 2014
2012-06-07
... Index, Equity and Currency Options) to extend a pilot program that eliminates minimum value sizes for... FLEX Options, FLEX currency options are also traded on the Exchange. These flexible index, equity, and currency options provide investors the ability to customize basic option features including size...
NASA Technical Reports Server (NTRS)
Kanning, G.
1975-01-01
A digital computer program written in FORTRAN is presented that implements the system identification theory for deterministic systems using input-output measurements. The user supplies programs simulating the mathematical model of the physical plant whose parameters are to be identified. The user may choose any one of three options. The first option allows for a complete model simulation for fixed input forcing functions. The second option identifies up to 36 parameters of the model from wind tunnel or flight measurements. The third option performs a sensitivity analysis for up to 36 parameters. The use of each option is illustrated with an example using input-output measurements for a helicopter rotor tested in a wind tunnel.
ERIC Educational Resources Information Center
North Carolina State Dept. of Public Education, Raleigh.
SUPERSTARS III is a K-8 program designed as an enrichment opportunity for self-directed learners in mathematics. The basic purpose of SUPERSTARS III is to provide the extra challenge that self-motivated students need in mathematics and to do so in a structured, long-term program that does not impinge on the normal classroom routine or the…
ERIC Educational Resources Information Center
North Carolina State Dept. of Public Education, Raleigh.
SUPERSTARS III is a K-8 program designed as an enrichment opportunity for self-directed learners in mathematics. The basic purpose of SUPERSTARS III is to provide the extra challenge that self-motivated students need in mathematics and to do so in a structured, long-term program that does not impinge on the normal classroom routine or the…
ERIC Educational Resources Information Center
North Carolina State Dept. of Public Education, Raleigh.
SUPERSTARS III is a K-8 program designed as an enrichment opportunity for self-directed learners in mathematics. The basic purpose of SUPERSTARS III is to provide the extra challenge that self-motivated students need in mathematics and to do so in a structured, long-term program that does not impinge on the normal classroom routine or the…
2006-09-30
unlimited. Prepared for: Naval Postgraduate School, Monterey, California 93943 Integrated Portfolio Analysis : Return on Investment and Real Options... Analysis of Intelligence Information Systems (Cryptologic Carry On Program) 30 September 2006 by LCDR Cesar G. Rios, Jr., Naval Postgraduate...October 2005 – 30 September 2006 4. TITLE AND SUBTITLE Integrated Portfolio Analysis : Return on Investment and Real Options Analysis of Intelligence
A Kramers-Moyal Approach to the Analysis of Third-Order Noise with Applications in Option Valuation
Popescu, Dan M.; Lipan, Ovidiu
2015-01-01
We propose the use of the Kramers-Moyal expansion in the analysis of third-order noise. In particular, we show how the approach can be applied in the theoretical study of option valuation. Despite Pawula’s theorem, which states that a truncated model may exhibit poor statistical properties, we show that for a third-order Kramers-Moyal truncation model of an option’s and its underlier’s price, important properties emerge: (i) the option price can be written in a closed analytical form that involves the Airy function, (ii) the price is a positive function for positive skewness in the distribution, (iii) for negative skewness, the price becomes negative only for price values that are close to zero. Moreover, using third-order noise in option valuation reveals additional properties: (iv) the inconsistencies between two popular option pricing approaches (using a “delta-hedged” portfolio and using an option replicating portfolio) that are otherwise equivalent up to the second moment, (v) the ability to develop a measure R of how accurately an option can be replicated by a mixture of the underlying stocks and cash, (vi) further limitations of second-order models revealed by introducing third-order noise. PMID:25625856
International Space Programs. Aerospace Education III.
ERIC Educational Resources Information Center
Bulmer, S. B.
This book, one in the series on Aerospace Education III, is a collection of the diverse information available regarding the international space programs. The five goals listed for the book are: to examine the Soviet space program, to understand the future of Soviet space activity, to examine other national and international space programs, to…
18 CFR 806.23 - Standards for water withdrawals.
Code of Federal Regulations, 2010 CFR
2010-04-01
... of groundwater or stream flow levels; rendering competing supplies unreliable; affecting other water..., at its own expense, an alternate water supply or other mitigating measures. (iii) Require the project... deficiencies, identify alternative water supply options, and support existing and proposed future withdrawals. ...
Code of Federal Regulations, 2012 CFR
2012-07-01
... (c)(12)(iii) of this section. If the latter reporting option is chosen, you must report: (i) Annual... flow meter's primary element (e.g., the orifice plate), or when there is only a differential pressure...
46 CFR 308.546 - Standard optional endorsement No. 1-A, Form MA-316-A.
Code of Federal Regulations, 2010 CFR
2010-10-01
.... 308.546 Section 308.546 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Cargo Insurance Iii-Facultative War Risk Cargo Insurance § 308.546... from the American War Risk Agency or MARAD. ...
46 CFR 308.546 - Standard optional endorsement No. 1-A, Form MA-316-A.
Code of Federal Regulations, 2011 CFR
2011-10-01
.... 308.546 Section 308.546 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Cargo Insurance Iii-Facultative War Risk Cargo Insurance § 308.546... from the American War Risk Agency or MARAD. ...
46 CFR 308.546 - Standard optional endorsement No. 1-A, Form MA-316-A.
Code of Federal Regulations, 2013 CFR
2013-10-01
.... 308.546 Section 308.546 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Cargo Insurance Iii-Facultative War Risk Cargo Insurance § 308.546... from the American War Risk Agency or MARAD. ...
46 CFR 308.546 - Standard optional endorsement No. 1-A, Form MA-316-A.
Code of Federal Regulations, 2012 CFR
2012-10-01
.... 308.546 Section 308.546 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Cargo Insurance Iii-Facultative War Risk Cargo Insurance § 308.546... from the American War Risk Agency or MARAD. ...
DOT National Transportation Integrated Search
1981-09-01
Volume III is the third and last volume of a three volume document describing the computer program HEVSIM. This volume includes appendices which list the HEVSIM program, sample part data, some typical outputs and updated nomenclature.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Haas, J.C.; Olivo, C.A.; Wilson, K.B.
1994-04-01
An experimental test plan has been prepared for DOE/METC review and approval to develop a filter media suitable for multi-contaminant control in granular-bed filter (GBF) applications. The plan includes identification, development, and demonstration of methods for enhanced media morphology, chemical reactivity, and mechanical strength. The test plan includes media preparation methods, physical and chemical characterization methods for fresh and reacted media, media evaluation criteria, details of test and analytical equipment, and test matrix of the proposed media testing. A filter media composed of agglomerated limestone and clay was determined to be the best candidate for multi-contaminate control in GBF operation.more » The combined limestone/clay agglomerate has the potential to remove sulfur and alkali species, in addition to particulate, and possibly halogens and trace heavy metals from coal process streams.« less
UAVSAR Program: Initial Results from New Instrument Capabilities
NASA Technical Reports Server (NTRS)
Lou, Yunling; Hensley, Scott; Moghaddam, Mahta; Moller, Delwyn; Chapin, Elaine; Chau, Alexandra; Clark, Duane; Hawkins, Brian; Jones, Cathleen; Marks, Phillip;
2013-01-01
UAVSAR is an imaging radar instrument suite that serves as NASA's airborne facility instrument to acquire scientific data for Principal Investigators as well as a radar test-bed for new radar observation techniques and radar technology demonstration. Since commencing operational science observations in January 2009, the compact, reconfigurable, pod-based radar has been acquiring L-band fully polarimetric SAR (POLSAR) data with repeat-pass interferometric (RPI) observations underneath NASA Dryden's Gulfstream-III jet to provide measurements for science investigations in solid earth and cryospheric studies, vegetation mapping and land use classification, archaeological research, soil moisture mapping, geology and cold land processes. In the past year, we have made significant upgrades to add new instrument capabilities and new platform options to accommodate the increasing demand for UAVSAR to support scientific campaigns to measure subsurface soil moisture, acquire data in the polar regions, and for algorithm development, verification, and cross-calibration with other airborne/spaceborne instruments.
[Necessary and unnecessary treatment options for hemorrhoids].
Zindel, Joel; Inglin, Roman; Brügger, Lukas
2014-12-01
Up to one third of the general population suffers from symptoms caused by hemorrhoids. Conservative treatment comes first unless the patient presents with an acute hemorrhoidal prolapse or a thrombosis. A fiber enriched diet is the primary treatment option, recommended in the perioperative period as well as a long-term prophylaxis. A timely limited application of topical ointments or suppositories and/or flavonoids are further treatment options. When symptoms persist interventional procedures for grade I-II hemorrhoids, and surgery for grade III-IV hemorrhoids should be considered. Rubber band ligation is the interventional treatment of choice. A comparable efficacy using sclerosing or infrared therapy has not yet been demonstrated. We therefore do not recommend these treatment options for the cure of hemorrhoids. Self-treatment by anal insertion of bougies is of lowrisk and may be successful, particularly in the setting of an elevated sphincter pressure. Anal dilation, sphincterotomy, cryosurgery, bipolar diathermy, galvanic electrotherapy, and heat therapy should be regarded as obsolete given the poor or missing data reported for these methods. For a long time, the classic excisional hemorrhoidectomy was considered to be the gold standard as far as surgical procedures are concerned. Primary closure (Ferguson) seems to be superior compared to the "open" version (Milligan Morgan) with respect to postoperative pain and wound healing. The more recently proposed stapled hemorrhoidopexy (Longo) is particularly advisable for circular hemorrhoids. Compared to excisional hemorrhoidectomy the Longo-operation is associated with reduced postoperative pain, shorter operation time and hospital stay as well as a faster recovery, with the disadvantage though of a higher recurrence rate. Data from Hemorrhoidal Artery Ligation (HAL)-, if appropriate in combination with a Recto-Anal Repair (HAL/RAR)-, demonstrates a similar trend towards a better tolerance of the procedure at the expense of a higher recurrence rate. These relatively "new" procedures equally qualify for the treatment of grade III and IV hemorrhoids, and, in the case of stapled hemorrhoidopexy, may even be employed in the emergency situation of an acute anal prolapse. While under certain circumstances different treatment options are equivalent, there is a clear specificity with respect to the application of those procedures in other situations. The respective pros and cons need to be discussed separately with every patient. According to their own requirements a treatment strategy has to be defined according to their individual requirements.
Gaining Options: A Mathematics Program for Potentially Talented At-Risk Adolescent Girls
ERIC Educational Resources Information Center
Reid, Pamela Trotman; Roberts, Sally K.
2006-01-01
In response to indicators that a decline in interest in mathematics occurs among girls--particularly those from low-income and minority groups--during middle school, the GO-GIRL (Gaining Options: Girls Investigate Real Life) program was designed to help potentially talented at-risk girls. The program aimed to build mathematical confidence, skills,…
Federal Register 2010, 2011, 2012, 2013, 2014
2013-01-07
... Effectiveness of Proposed Rule Change To Extend the Penny Pilot Program December 31, 2012. Pursuant to Section... certain options in pennies (the ``Penny Pilot Program'') and to adopt a procedure for replacing in the Penny Pilot Program option classes that have been delisted. The text of the proposed rule change is...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-06-27
... Rule Change To Extend the Penny Pilot Program June 21, 2013. Pursuant to Section 19(b)(1) of the... options in pennies (``Penny Pilot Program'') and to revise the provision describing how the Exchange specifies which option classes trade in the Penny Pilot Program. The text of the proposed rule change is...
Federal Register 2010, 2011, 2012, 2013, 2014
2012-07-06
... Rule Change To Extend the Penny Pilot Program June 29, 2012. Pursuant to Section 19(b)(1) \\1\\ of the... program to quote and to trade certain options in pennies (``Penny Pilot Program''). The text of the... penny pilot issues that have been delisted with the next most actively traded multiply listed options...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-12-09
... Effectiveness of Proposed Rule Change To Extend the Penny Pilot Program December 3, 2013. Pursuant to Section 19... certain options in pennies (the ``Penny Pilot Program''). The text of the proposed rule change is... quoting and trading of certain option classes in penny increments (the ``Penny Pilot Program'' or...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-06-24
... Effectiveness of Proposed Rule Change to Extend the Penny Pilot Program June 18, 2013. Pursuant to Section 19(b... Policies .01 to extend the pilot program for the quoting and trading of certain options in pennies (the ``Penny Pilot Program'') and to revise the provision describing how the Exchange specifies which option...
Federal Register 2010, 2011, 2012, 2013, 2014
2012-12-05
... Rule Change Regarding the Short Term Option Series Program November 29, 2012. Pursuant to Section 19(b... number of expirations available under the Short Term Option Series Program (``STOS Program''), to allow for the Exchange to delist certain series in the STOS that do not have open interest and to expand the...
Developing fire management mixes for fire program planning
Armando González-Cabán; Patricia B. Shinkle; Thomas J. Mills
1986-01-01
Evaluating economic efficiency of fire management program options requires information on the firefighting inputs, such as vehicles and crews, that would be needed to execute the program option selected. An algorithm was developed to translate automatically dollars allocated to type of firefighting inputs to numbers of units, using a set of weights for a specific fire...
Trojan, Jörg; Waidmann, Oliver
2016-01-01
Sorafenib is still the only systemic drug approved for the treatment of advanced hepatocellular carcinoma (HCC). In recent years, several investigational agents mainly targeting angiogenesis failed in late-phase clinical development due to either toxicity or lack of benefit. Recently, data of the RESORCE trial, a placebo-controlled Phase III study that evaluated the efficacy and safety of regorafenib in patients with HCC and documented disease progression after systemic first-line treatment with sorafenib, were presented at the ESMO World Congress on Gastrointestinal Cancer, 2016. Regorafenib treatment resulted in a 2.8-month survival benefit compared to placebo (10.6 months vs 7.8 months). Side effects were consistent with the known profile of regorafenib. The approval of regorafenib for this indication is expected in 2017. Further candidate agents in Phase III evaluation for second-line treatment of patients with HCC are the MET inhibitors tivantinib and cabozantinib, the vascular endothelial growth factor receptor-2 antibody ramucirumab, and the programmed death receptor-1 (PD-1) blocking antibody pembrolizumab. Furthermore, results from two first-line trials with either the tyrosine kinase inhibitor lenvatinib or the PD-1 antibody nivolumabin in comparison to sorafenib are awaited in the near future and might further change the treatment sequence of advanced HCC. PMID:27703962
Trojan, Jörg; Waidmann, Oliver
2016-01-01
Sorafenib is still the only systemic drug approved for the treatment of advanced hepatocellular carcinoma (HCC). In recent years, several investigational agents mainly targeting angiogenesis failed in late-phase clinical development due to either toxicity or lack of benefit. Recently, data of the RESORCE trial, a placebo-controlled Phase III study that evaluated the efficacy and safety of regorafenib in patients with HCC and documented disease progression after systemic first-line treatment with sorafenib, were presented at the ESMO World Congress on Gastrointestinal Cancer, 2016. Regorafenib treatment resulted in a 2.8-month survival benefit compared to placebo (10.6 months vs 7.8 months). Side effects were consistent with the known profile of regorafenib. The approval of regorafenib for this indication is expected in 2017. Further candidate agents in Phase III evaluation for second-line treatment of patients with HCC are the MET inhibitors tivantinib and cabozantinib, the vascular endothelial growth factor receptor-2 antibody ramucirumab, and the programmed death receptor-1 (PD-1) blocking antibody pembrolizumab. Furthermore, results from two first-line trials with either the tyrosine kinase inhibitor lenvatinib or the PD-1 antibody nivolumabin in comparison to sorafenib are awaited in the near future and might further change the treatment sequence of advanced HCC.
Aerospace engineering educational program
NASA Technical Reports Server (NTRS)
Craft, William; Klett, David; Lai, Steven
1992-01-01
The principle goal of the educational component of NASA CORE is the creation of aerospace engineering options in the mechanical engineering program at both the undergraduate and graduate levels. To accomplish this goal, a concerted effort during the past year has resulted in detailed plans for the initiation of aerospace options in both the BSME and MSME programs in the fall of 1993. All proposed new courses and the BSME aerospace option curriculum must undergo a lengthy approval process involving two cirriculum oversight committees (School of Engineering and University level) and three levels of general faculty approval. Assuming approval is obtained from all levels, the options will officially take effect in Fall '93. In anticipation of this, certain courses in the proposed curriculum are being offered during the current academic year under special topics headings so that current junior level students may graduate in May '94 under the BSME aerospace option. The proposed undergraduate aerospace option curriculum (along with the regular mechanical engineering curriculum for reference) is attached at the end of this report, and course outlines for the new courses are included in the appendix.
Preliminary Results From the C-Pulse OPTIONS HF European Multicenter Post-Market Study.
Schulz, Antonia; Krabatsch, Thomas; Schmitto, Jan D; Hetzer, Roland; Seidel, Mirko; Dohmen, Pascal M; Hotz, Holger
2016-02-18
BACKGROUND The C-Pulse System is an extra-aortic balloon counterpulsation device. It is used to treat patients with heart failure disease in NYHA functional class III or ambulatory class IV. MATERIAL AND METHODS We present preliminary site-reported 6-month data from 3 centers in Germany as part of the prospective observational post-market OPTIONS HF study. RESULTS Between May 2013 and March 2014, the C-Pulse System was implanted in 8 patients (7 male) with a mean age of 61.6±9.3 years. Four had ischemic and 4 had non-ischemic cardiomyopathy. No stroke, myocardial infarction, major bleeding, or major infection due to the device were reported. One patient developed non-device-related refractory tachycardia with worsening heart failure 12 h after surgery and underwent left ventricular assist device implantation. Within 6 months of observation, functional status improved from NYHA III to II in 5 patients, and 2 remained in NYHA III. Mean left ventricular ejection fraction increased from 24.3±7.9% to 44.5±4.5% (p<0.0001). Mean Kansas City Cardiomyopathy Questionnaire overall score improved from 28.6±19.1 to 59.1±22.5 (p=0.0183). Six-minute walk test was performed in 6 out of 7 patients at follow-up. The mean distance improved from 252.0±85.1 m to 279.2±87.5 m (p>0.05). One patient was weaned off the device after 6 months of support. CONCLUSIONS The C-Pulse System provides a therapeutic option for patients with moderate-to-severe heart failure and seems to improve quality of life and cardiac function over time.
Nontraditional Options Workshop. Participants Workbook.
ERIC Educational Resources Information Center
Pierce, Beth Ann, Comp.
This workbook presents materials for a Nontraditional Options Workshop designed to introduce women to predominantly male vocational programs and careers. The workshop provides career awareness, vocational information, and hands-on exploration of nontraditional programs offered at Blackhawk Technical College (BTC), Wisconsin. Introductory materials…
Federal Register 2010, 2011, 2012, 2013, 2014
2013-06-28
... Permit BX Options To Accept Inbound Options Orders From NASDAQ OMX PHLX LLC and NASDAQ Options Market... permanent approval of the Exchange's pilot program that permits the BX Options System to accept inbound orders routed by Nasdaq Options Services LLC (``NOS'') from the NASDAQ OMX PHLX LLC (``PHLX'') and The...
Tyk2 as a target for immune regulation in human viral/bacterial pneumonia.
Berg, Johanna; Zscheppang, Katja; Fatykhova, Diana; Tönnies, Mario; Bauer, Torsten T; Schneider, Paul; Neudecker, Jens; Rückert, Jens C; Eggeling, Stephan; Schimek, Maria; Gruber, Achim D; Suttorp, Norbert; Hippenstiel, Stefan; Hocke, Andreas C
2017-07-01
The severity and lethality of influenza A virus (IAV) infections is frequently aggravated by secondary bacterial pneumonia. However, the mechanisms in human lung tissue that provoke this increase in fatality are unknown and therapeutic immune modulatory options are lacking.We established a human lung ex vivo co-infection model to investigate innate immune related mechanisms contributing to the susceptibility of secondary pneumococcal pneumonia.We revealed that type I and III interferon (IFN) inhibits Streptococcus pneumoniae -induced interleukin (IL)-1β release. The lack of IL-1β resulted in the repression of bacterially induced granulocyte-macrophage colony-stimulating factor (GM-CSF) liberation. Specific inhibition of IFN receptor I and III-associated tyrosine kinase 2 (Tyk2) completely restored the S. pneumoniae -induced IL-1β-GM-CSF axis, leading to a reduction of bacterial growth. A preceding IAV infection of the human alveolus leads to a type I and III IFN-dependent blockade of the early cytokines IL-1β and GM-CSF, which are key for orchestrating an adequate innate immune response against bacteria. Their virally induced suppression may result in impaired bacterial clearance and alveolar repair.Pharmacological inhibition of Tyk2 might be a new treatment option to sustain beneficial endogenous GM-CSF levels in IAV-associated secondary bacterial pneumonia. Copyright ©ERS 2017.
Nuclear Fuel Cycle Options Catalog: FY16 Improvements and Additions
DOE Office of Scientific and Technical Information (OSTI.GOV)
Price, Laura L.; Barela, Amanda Crystal; Schetnan, Richard Reed
2016-08-31
The United States Department of Energy, Office of Nuclear Energy, Fuel Cycle Technology Program sponsors nuclear fuel cycle research and development. As part of its Fuel Cycle Options campaign, the DOE has established the Nuclear Fuel Cycle Options Catalog. The catalog is intended for use by the Fuel Cycle Technologies Program in planning its research and development activities and disseminating information regarding nuclear energy to interested parties. The purpose of this report is to document the improvements and additions that have been made to the Nuclear Fuel Cycle Options Catalog in the 2016 fiscal year.
Burkhart, Diane N; Lischka, Terri A
2011-04-01
Students in colleges of osteopathic medicine have several options when considering postdoctoral training programs. In addition to training programs approved solely by the American Osteopathic Association or accredited solely by the Accreditation Council for Graduate Medical Education (ACGME), students can pursue programs accredited by both organizations (ie, dually accredited programs) or osteopathic programs that occur side-by-side with ACGME programs (ie, parallel programs). In the present article, we report on the availability and growth of these 2 training options and describe their benefits and drawbacks for trainees and the osteopathic medical profession as a whole.
A System Dynamics Approach for the Selection of Contaminated Land Management Options
NASA Astrophysics Data System (ADS)
McKnight, U. S.; Kuebert, M.; Finkel, M.; Bieg, M.
2006-12-01
Large-scale contaminated land and groundwater is a widespread problem that can severely impact human health, the environment and the economy at many urban sites all over the world. Usually a considerable number of potential management solutions exist at each of these sites. A detailed investigation of all these options, however, is not economically feasible which makes streamlining of the planning and decision process a mandatory requirement. Decisions to be taken should be made as early as possible in order to reduce expenditures on site investigation. Therefore, a tiered decision-making procedure is required, including (i) identification and prioritization of focal areas of risks, (ii) feasibility screening of remediation targets and available management alternatives to narrow the range of possible options for (iii) subsequent detailed investigations of only a select group of preferable options. For each of these elements, tailored decision and investigation concepts are required. These concepts and applied methods should be specifically adapted to the type and scale of the particular decision to be taken- more target-oriented, cost-efficient investigation programs, as well as model-based assessment methods are needed (Ruegner et al. 2006). A gap exists within this framework with respect to preliminary assessment methodologies representing the first decision level. To fill this gap, a new system dynamics approach has been developed that represents the system of source- pathway-receptor sequences by means of a mass flux model. The dynamics are governed by the effects of possible remedial actions, which are described as mass flux change over time (Serapiglia et al. 2005). This approach has been implemented in the preliminary evaluation tool CARO-plus (Cost-efficiency Assessment of Remediation Options) that models the effects of potential remedial actions, including tackling the contaminant source and managing the groundwater plume. The model represents the causal relationships that exist between the state of the system, the effects of the technologies and their costs, and may considerably impact the outcome to be predicted. The tool enables a fast and effective "screening" of management scenarios using simplified approaches (analytical models). Replacing the concept of total cleanup of sites based on concentration standards, the evaluation tool contains risk modules that describe exposure pathways, i.e. transfer of contaminants from groundwater to the receptor "human being", in accordance to MEPAS (Strenge & Chamberlain 1995). As multiple lines of evidence may apply, the effects of remediation options can be analyzed on the basis of contaminant mass flux, concentrations, and/or risk indices (carcinogenic/noncarcinogenic). Costs are calculated in terms of net present values. Uncertainty is taken into account using Monte-Carlo sensitivity analyses. In the presentation, examples will be shown for how the proposed approach helps to pre-select compatible remediation options by giving an overview to the following set of questions: (i) what is the time scale for risks expected at a particular site, (ii) does the scenario reduce/control risk at the receptor, (iii) is the scenario compatible with cleanup objectives (e.g. in the case that concentration standards are still required for specific compounds present at a site), (iv) does the scenario satisfy cost objectives and can therefore be considered financially viable, (v) is the scenario acceptable to regulators and the community, and (vi) what factors are most critical to the decision-making process.
ERIC Educational Resources Information Center
Cohen, Arthur M.; Brawer, Florence B.; Kozeracki, Carol A.
This final report for the JumpStart III program presents a summary of the entrepreneurship training programs developed by each of the four JumpStart III partners selected in March 1997. Grants for the colleges totaled $354,546 over 2 years. The Jumpstart funding has been only a starting point for these and the other 12 Jumpstart partners in…
40 CFR 147.2650 - State-administered program-Class I, II, III, IV, and V wells.
Code of Federal Regulations, 2010 CFR
2010-07-01
... CONTROL PROGRAMS Puerto Rico § 147.2650 State-administered program—Class I, II, III, IV, and V wells. The Underground Injection Control Program for all classes of wells in the Commonwealth of Puerto Rico, other than those on Indian lands, is the program administered by Puerto Rico's Environmental Quality Board (EQB...
40 CFR 147.2650 - State-administered program-Class I, II, III, IV, and V wells.
Code of Federal Regulations, 2011 CFR
2011-07-01
... CONTROL PROGRAMS Puerto Rico § 147.2650 State-administered program—Class I, II, III, IV, and V wells. The Underground Injection Control Program for all classes of wells in the Commonwealth of Puerto Rico, other than those on Indian lands, is the program administered by Puerto Rico's Environmental Quality Board (EQB...
40 CFR 147.2650 - State-administered program-Class I, II, III, IV, and V wells.
Code of Federal Regulations, 2013 CFR
2013-07-01
... CONTROL PROGRAMS Puerto Rico § 147.2650 State-administered program—Class I, II, III, IV, and V wells. The Underground Injection Control Program for all classes of wells in the Commonwealth of Puerto Rico, other than those on Indian lands, is the program administered by Puerto Rico's Environmental Quality Board (EQB...
ESEA, Title III Dissemination Program Evaluation Report, 1972-73, 1973-74. Sections I and II.
ERIC Educational Resources Information Center
Soper, Dorothy B.
This report evaluates the New Jersey ESEA Title III dissemination program during its first two years, 1972-74. Purposes of the program are to (a) determine if essential elements of successful education programs can be transferred from originating districts to adopter districts while yielding comparable student gains, and (b) provide educators with…
Cetuximab in locally advanced head-and-neck cancer: defining the population
Ho, C.
2010-01-01
Encouraging data for targeted therapy in head-and-neck squamous cell carcinoma are opening new options for treatment. Phase III trials of cetuximab, an antibody directed against the epidermal growth factor receptor (egfr) have demonstrated benefit in the locally advanced and metastatic settings. Recognizing the importance of emerging therapies, Cancer Care Ontario published guideline recommendations for egfr-targeted therapy in stage iii and iv head-and-neck cancer. The present paper takes a further look at the population for whom an offer of cetuximab therapy may be appropriate. PMID:20697514
DSN command system Mark III-78. [data processing
NASA Technical Reports Server (NTRS)
Stinnett, W. G.
1978-01-01
The Deep Space Network command Mark III-78 data processing system includes a capability for a store-and-forward handling method. The functions of (1) storing the command files at a Deep Space station; (2) attaching the files to a queue; and (3) radiating the commands to the spacecraft are straightforward. However, the total data processing capability is a result of assuming worst case, failure-recovery, or nonnominal operating conditions. Optional data processing functions include: file erase, clearing the queue, suspend radiation, command abort, resume command radiation, and close window time override.
Lang, Carrie L; Simon, Diane; Kilgore, Jane
The American College of Surgeons Committee on Trauma revised the Resources for Optimal Care of the Injured Patient to include the criteria for trauma centers to participate in a risk-adjusted benchmarking system. Trauma Quality Improvement Program is currently the risk-adjusted benchmarking program sponsored by the American College of Surgeons, which will be required of all trauma centers to participate in early 2017. Prior to this, there were no risk-adjusted programs for Level III verified trauma centers. The Ohio Society of Trauma Nurse Leaders is a collaborative group made up of trauma program managers, coordinators, and other trauma leaders who meet 6 times a year. Within this group, a Level III Subcommittee was formed initially to provide a place for the Level III centers to discuss issues specific to the Level III centers. When the new requirement regarding risk-adjustment became official, the subcommittee agreed to begin reporting simple data points with the idea to risk adjust in the future.
77 FR 25319 - Commodity Options
Federal Register 2010, 2011, 2012, 2013, 2014
2012-04-27
... marketing loan program would not be considered swaps.\\25\\ \\25\\ After CFTC staff reviewed the ``options to redeem'' with both USDA staff members responsible for managing the cotton marketing loan program and industry representatives from Amcot (an association of US cotton marketing cooperatives), the Commission...
Specializations in Rehabilitation Counseling: One Program's Vision
ERIC Educational Resources Information Center
Bernacchio, Charles; Burker, Eileen J.; Falvo, Donna; Porter, Patricia; Carone, Stacia
2008-01-01
The option for specialization is explored to address expanding roles for rehabilitation counselors. Several important considerations are identified for Rehabilitation Counselor Education (RCE) program faculty opting for a specialization. Development of specialty tracks in psychiatric and developmental disabilities are offered as viable options for…
DOT National Transportation Integrated Search
1981-09-01
Volume III is the third and last volume of a three volume document describing the computer program HEVSIM. This volume includes appendices which list the HEVSIM program, sample part data, some typical outputs and updated nomenclature.
48 CFR 234.004 - Acquisition strategy.
Code of Federal Regulations, 2010 CFR
2010-10-01
... acquisition strategy. The documentation— (A) Shall include an explanation of the level of program risk; and (B... the reasons for proceeding with Milestone B approval despite the high level of program risk; and (iii...'s written determination that— (A) The program is so complex and technically challenging that it...
31 CFR 344.2 - What general provisions apply to SLGS securities?
Code of Federal Regulations, 2010 CFR
2010-07-01
... program to create a cost-free option; (ii) To purchase a SLGS security with any amount received from the... would result in the SLGS program being used to create a cost-free option. In addition, this practice is... ability to cancel in these circumstances would result in the SLGS program being used to create a cost-free...
31 CFR 344.2 - What general provisions apply to SLGS securities?
Code of Federal Regulations, 2013 CFR
2013-07-01
... program to create a cost-free option; (ii) To purchase a SLGS security with any amount received from the... would result in the SLGS program being used to create a cost-free option. In addition, this practice is... ability to cancel in these circumstances would result in the SLGS program being used to create a cost-free...
31 CFR 344.2 - What general provisions apply to SLGS securities?
Code of Federal Regulations, 2011 CFR
2011-07-01
... program to create a cost-free option; (ii) To purchase a SLGS security with any amount received from the... would result in the SLGS program being used to create a cost-free option. In addition, this practice is... ability to cancel in these circumstances would result in the SLGS program being used to create a cost-free...
Federal Register 2010, 2011, 2012, 2013, 2014
2010-07-09
... stocks on which option series may be listed at $1 strike price intervals. To be eligible for inclusion in..., 2003) (SR-Phlx-2002-55) (approval of pilot program). The Strike Program was then extended several times... option series with $1 strike price intervals for any class selected for the program, except as...
"Children's Health Care, Parts 1-4." Options in Education Takes Listeners to the Core of the Issues.
ERIC Educational Resources Information Center
George Washington Univ., Washington, DC. Inst. for Educational Leadership.
The scripts of four programs of National Public Radio's Options in Education series are presented. The first program has sequences involving the use of high technology in childbirth. Interviews with doctors and expectant mothers explore the use and availability of electronic monitoring equipment in prenatal care. In the second program, the high…
Federal Register 2010, 2011, 2012, 2013, 2014
2010-12-10
... Rule Change Related to the Penny Pilot Program December 3, 2010. Pursuant to Section 19(b)(1) of the... relating to the Penny Pilot Program. The text of the proposed rule change is available on the Exchange's... language regarding the Penny Pilot Program tracks that of the language of Chicago Board Options Exchange...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-01-07
... Change Relating to the Exchange Penny Pilot Program December 31, 2012. Pursuant to Section 19(b)(1) \\1... Penny Pilot Program. The text of the proposed rule change is provided below. [(additions are italicized... increments for bids and offers for all series of the option classes participating in the Penny Pilot Program...
Code of Federal Regulations, 2010 CFR
2010-04-01
... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Options. 35.120 Section 35.120... and Definitions for All Programs. § 35.120 Options. (a) Standard treatments. Where interim controls are required by this part, the designated party has the option to presume that lead-based paint or...
42 CFR 436.201 - Individuals included in optional groups.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 42 Public Health 4 2010-10-01 2010-10-01 false Individuals included in optional groups. 436.201... SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS ELIGIBILITY IN GUAM, PUERTO RICO, AND THE VIRGIN ISLANDS Options for Coverage as Categorically Needy § 436.201 Individuals included in optional groups. (a) The...
Federal Register 2010, 2011, 2012, 2013, 2014
2012-11-21
...-Regulatory Organizations; Chicago Board Options Exchange, Incorporated; Notice of Filing and Immediate Effectiveness of a Proposed Rule Change To Amend the Weekly Options Program November 15, 2012. Pursuant to... is hereby given that, on November 9, 2012, the Chicago Board Options Exchange, Incorporated (the...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-09-12
... Rule Change Relating to $0.50 and $1 Strike Price Intervals for Classes in the Short Term Option Series... options classes that trade in one dollar increments and are in the Short Term Option Series Program... business day, series of options on no more than thirty option classes that expire on each of the next five...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-05-30
... Change Relating to $0.50 and $1 Strike Price Intervals for Classes in the Short Term Option Series... amend Rule 1012 (Series of Options Open for Trading) and Rule 1101A (Terms of Option Contracts) to give... Term Option Series Program (referred to as a ``Related non-Short Term Option series''), for the Related...
Federal Register 2010, 2011, 2012, 2013, 2014
2010-10-14
...] Solicitation of Applications for the Public Works, Economic Adjustment Assistance, and Global Climate Change... Program; and (iii) Global Climate Change Mitigation Incentive Fund (GCCMIF) Program. To enhance the...; and (iii) Global Climate Change Mitigation Incentive Fund (GCCMIF) Program. EDA will publish separate...
Code of Federal Regulations, 2010 CFR
2010-10-01
... ELIGIBILITY IN GUAM, PUERTO RICO, AND THE VIRGIN ISLANDS Options for Coverage as Categorically Needy Options... programs. The agency may provide Medicaid to any group or groups of individuals specified under § 436.201(a...
School Management Options for American Indians.
ERIC Educational Resources Information Center
Streiff, Paul R.
In response to the Presidential/Secretarial Educational Objective of 1975 which called for a statement from American Indian communities relative to their educational management preferences, the Office of Indian Education Programs (OIEP) established a program for gathering and disseminating educational management options to Indian people. A seven…
34 CFR 300.110 - Program options.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 34 Education 2 2011-07-01 2010-07-01 true Program options. 300.110 Section 300.110 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND REHABILITATIVE SERVICES, DEPARTMENT OF EDUCATION ASSISTANCE TO STATES FOR THE EDUCATION OF CHILDREN WITH...
45 CFR 1306.34 - Combination program option.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 45 Public Welfare 4 2012-10-01 2012-10-01 false Combination program option. 1306.34 Section 1306.34 Public Welfare Regulations Relating to Public Welfare (Continued) OFFICE OF HUMAN DEVELOPMENT SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES THE ADMINISTRATION FOR CHILDREN, YOUTH AND FAMILIES, HEAD...
45 CFR 1306.34 - Combination program option.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 45 Public Welfare 4 2013-10-01 2013-10-01 false Combination program option. 1306.34 Section 1306.34 Public Welfare Regulations Relating to Public Welfare (Continued) OFFICE OF HUMAN DEVELOPMENT SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES THE ADMINISTRATION FOR CHILDREN, YOUTH AND FAMILIES, HEAD...
45 CFR 1306.34 - Combination program option.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 45 Public Welfare 4 2014-10-01 2014-10-01 false Combination program option. 1306.34 Section 1306.34 Public Welfare Regulations Relating to Public Welfare (Continued) OFFICE OF HUMAN DEVELOPMENT SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES THE ADMINISTRATION FOR CHILDREN, YOUTH AND FAMILIES, HEAD...
45 CFR 1306.34 - Combination program option.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 45 Public Welfare 4 2011-10-01 2011-10-01 false Combination program option. 1306.34 Section 1306.34 Public Welfare Regulations Relating to Public Welfare (Continued) OFFICE OF HUMAN DEVELOPMENT SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES THE ADMINISTRATION FOR CHILDREN, YOUTH AND FAMILIES, HEAD...
75 FR 30385 - Defense Transportation Regulation, Part IV
Federal Register 2010, 2011, 2012, 2013, 2014
2010-06-01
... extensions will be considered due to the timelines associated with funding and programming future Phase III... extensions will be considered due to the timelines associated with funding and programming future Phase III...
2008-10-03
This final rule provides guidance to States that want to administer self-directed personal assistance services through their State Plans, as authorized by the Deficit Reduction Act of 2005. The State plan option allows beneficiaries, through an approved self-directed services plan and budget, to purchase personal assistance services. The rule also provides guidance to ensure beneficiary health and welfare and financial accountability of the State Plan option.
GBM heterogeneity as a function of variable epidermal growth factor receptor variant III activity.
Lindberg, Olle R; McKinney, Andrew; Engler, Jane R; Koshkakaryan, Gayane; Gong, Henry; Robinson, Aaron E; Ewald, Andrew J; Huillard, Emmanuelle; David James, C; Molinaro, Annette M; Shieh, Joseph T; Phillips, Joanna J
2016-11-29
Abnormal activation of the epidermal growth factor receptor (EGFR) due to a deletion of exons 2-7 of EGFR (EGFRvIII) is a common alteration in glioblastoma (GBM). While this alteration can drive gliomagenesis, tumors harboring EGFRvIII are heterogeneous. To investigate the role for EGFRvIII activation in tumor phenotype we used a neural progenitor cell-based murine model of GBM driven by EGFR signaling and generated tumor progenitor cells with high and low EGFRvIII activation, pEGFRHi and pEGFRLo. In vivo, ex vivo, and in vitro studies suggested a direct association between EGFRvIII activity and increased tumor cell proliferation, decreased tumor cell adhesion to the extracellular matrix, and altered progenitor cell phenotype. Time-lapse confocal imaging of tumor cells in brain slice cultures demonstrated blood vessel co-option by tumor cells and highlighted differences in invasive pattern. Inhibition of EGFR signaling in pEGFRHi promoted cell differentiation and increased cell-matrix adhesion. Conversely, increased EGFRvIII activation in pEGFRLo reduced cell-matrix adhesion. Our study using a murine model for GBM driven by a single genetic driver, suggests differences in EGFR activation contribute to tumor heterogeneity and aggressiveness.
Findings from an Evaluation of a Comprehensive Parent Education Program for School-Age Parents.
ERIC Educational Resources Information Center
Braun, Maureen H.; Fuscaldo, Diane P.
This study evaluates the impact of the Parent Linking Project III (PLP III) on its participants. The PLP III is a comprehensive program for teenage mothers which offers workshops in parenting, mother-child interaction, and vocational awareness, and provides day care services that allow teen mothers to take the opportunity to complete their high…
76 FR 9820 - Notice of Information Collection
Federal Register 2010, 2011, 2012, 2013, 2014
2011-02-22
... . SUPPLEMENTARY INFORMATION: I. Abstract LaRC leadership desires to seek out customer feedback across all mission..., customers will have the option to provide their feedback via e-mail, Web-based survey, or phone conversation in accordance with their preference. III. Data Title: LaRC Customer Satisfaction Assessment OMB...
Computer program for calculation of oxygen uptake
NASA Technical Reports Server (NTRS)
Castle, B. L.; Castle, G.; Greenleaf, J. E.
1979-01-01
A description and operational precedures are presented for a computer program, written in Super Basic, that calculates oxygen uptake, carbon dioxide production, and related ventilation parameters. Program features include: (1) the option of entering slope and intercept values of calibration curves for the O2 and CO2 and analyzers; (2) calculation of expired water vapor pressure; and (3) the option of entering inspured O2 and CO2 concentrations. The program is easily adaptable for programmable laboratory calculators.
Navy CG(X) Cruiser Program: Background, Oversight Issues, and Options for Congress
2009-04-10
Options for Congress 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e . TASK NUMBER 5f. WORK...Sees Lessons in Shipbuilding Program Failures,” GovernmentExecutive.com, September 24, 2008) quoted Admiral Gary Roughead, the Chief of Naval...question is whether the schedule for procuring CG(X)s is properly aligned with foreign-country ballistic missile development programs. A 2005 defense
Navy CG(X) Cruiser Program: Background, Oversight Issues, and Options for Congress
2009-09-18
and Options for Congress 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e . TASK NUMBER 5f...October 27, 2008. Another press report (Katherine McIntire Peters, “Navy’s Top Officer Sees Lessons in Shipbuilding Program Failures... aligned with foreign-country ballistic missile development programs. A 2005 defense trade press report, for example, states that “navy officials
Fast Track Option: An Accelerated Associate's Degree Program.
ERIC Educational Resources Information Center
Price, J. Randall
1998-01-01
Alternative instructional delivery options such as self-paced and flexible enrollment courses are designed to increase enrollment, promote retention, and encourage student success without lowering academic standards. The Fast Track Associate's Degree Program, developed by a team of faculty, staff, and administrators at Richland Community College,…
Resource Sharing and Public Education. Project Evaluation Report.
ERIC Educational Resources Information Center
Leton, Donald A.
Two exemplary projects developed to maximize student options through the sharing of facilities, programs, and options were evaluated. The Remedial-Developmental Program developed a communications network between McKinley and Roosevelt High Schools and Kapiolani Community College to share student information and use it for individual student…
State Options for Supporting Delinquency Prevention: A Working Paper.
ERIC Educational Resources Information Center
Croan, Gerald M.; And Others
A supplement to the related document "Delinquency Prevention: Theories and Strategies," this paper analyzes the options for state agencies (particularly state planning agencies participating in the Law Enforcement Assistance Administration formula grant program) to promote and support program forms recommended in the companion document.…
45 CFR 1306.36 - Additional Head Start program option variations.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 45 Public Welfare 4 2013-10-01 2013-10-01 false Additional Head Start program option variations. 1306.36 Section 1306.36 Public Welfare Regulations Relating to Public Welfare (Continued) OFFICE OF HUMAN DEVELOPMENT SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES THE ADMINISTRATION FOR CHILDREN...
45 CFR 1306.36 - Additional Head Start program option variations.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 45 Public Welfare 4 2012-10-01 2012-10-01 false Additional Head Start program option variations. 1306.36 Section 1306.36 Public Welfare Regulations Relating to Public Welfare (Continued) OFFICE OF HUMAN DEVELOPMENT SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES THE ADMINISTRATION FOR CHILDREN...
45 CFR 1306.36 - Additional Head Start program option variations.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 45 Public Welfare 4 2011-10-01 2011-10-01 false Additional Head Start program option variations. 1306.36 Section 1306.36 Public Welfare Regulations Relating to Public Welfare (Continued) OFFICE OF HUMAN DEVELOPMENT SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES THE ADMINISTRATION FOR CHILDREN...
45 CFR 1306.36 - Additional Head Start program option variations.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 45 Public Welfare 4 2014-10-01 2014-10-01 false Additional Head Start program option variations. 1306.36 Section 1306.36 Public Welfare Regulations Relating to Public Welfare (Continued) OFFICE OF HUMAN DEVELOPMENT SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES THE ADMINISTRATION FOR CHILDREN...
NASA Technical Reports Server (NTRS)
Balasubramanian, Kunjithapatham; Shaklan, Stuart; Give'on, Amir; Cady, Eric; Marchen, Luis
2011-01-01
The NASA Exoplanet program and the Cosmic Origins program are exploring technical options to combine the visible to NIR performance requirements of a space coronagraph with the general astrophysics requirements of a space telescope covering the deep UV spectrum. Are there compatible options in terms of mirror coatings and telescope architecture to satisfy both goals? In this paper, we address some of the main concerns, particularly relating to polarization in the visible and throughput in the UV. Telescope architectures employing different coating options compatible with current technology are considered in this trade study.
Federal Register 2010, 2011, 2012, 2013, 2014
2013-12-24
...-Regulatory Organizations; Chicago Board Options Exchange, Incorporated; Notice of Filing and Immediate Effectiveness of a Proposed Rule Change Relating to the Credit Option Margin Pilot Program December 18, 2013... thereunder,\\2\\ notice is hereby given that on December 12, 2013, Chicago Board Options Exchange, Incorporated...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-12-20
...-Regulatory Organizations; Chicago Board Options Exchange, Incorporated; Notice of Filing and Immediate Effectiveness of a Proposed Rule Change Relating to the Short Term Option Series Program December 16, 2013... Rule 19b-4 thereunder,\\2\\ notice is hereby given that, on December 11, 2013, Chicago Board Options...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-11-23
... Rule To Increase the Number of Series Permitted Per Class in the Short Term Option Series Program November 17, 2011. I. Introduction On September 19, 2011, the Chicago Board Options Exchange, Incorporated... proposed rule change to increase the number of series permitted per class in the Short Term Options Series...
Distributed Energy Implementation Options
DOE Office of Scientific and Technical Information (OSTI.GOV)
Shah, Chandralata N
2017-09-13
This presentation covers the options for implementing distributed energy projects. It distinguishes between options available for distributed energy that is government owned versus privately owned, with a focus on the privately owned options including Energy Savings Performance Contract Energy Sales Agreements (ESPC ESAs). The presentation covers the new ESPC ESA Toolkit and other Federal Energy Management Program resources.
Federal Register 2010, 2011, 2012, 2013, 2014
2013-10-22
... The Exchange proposes to amend interpretive material to Rule 5050 (Series of Options Contracts Open... Proposed Rule Change 1. Purpose The Exchange proposes to amend IM-5050-6 to Rule 5050 (Series of Options... the strike price interval setting parameters for their Short Term Option Series (``STOS'') Programs...
Federal Register 2010, 2011, 2012, 2013, 2014
2010-02-04
... series.\\8\\ The annual report will also contain information and analysis of FLEX Options trading patterns... will also contain information and analysis of FLEX Options trading patterns, and index price volatility... To Establish a Pilot Program To Modify FLEX Option Exercise Settlement Values and Minimum Value Sizes...
ERIC Educational Resources Information Center
General Accounting Office, Washington, DC. Div. of Human Resources.
Thirty options for reducing guaranteed student loan defaults and related federal costs are provided by the General Accounting Office (GAO). The options are presented by groups of program participants: students, schools, lenders, guaranty agencies, and the Department of Education. These options include: adopt GAO's past recommendation to increase…
DOE Office of Scientific and Technical Information (OSTI.GOV)
Eckert-Gallup, Aubrey Celia; Lewis, John R.; Brooks, Dusty Marie
This report describes the methods, results, and conclusions of the analysis of 11 scenarios defined to exercise various options available in the xLPR (Extremely Low Probability of Rupture) Version 2 .0 code. The scope of the scenario analysis is three - fold: (i) exercise the various options and components comprising xLPR v2.0 and defining each scenario; (ii) develop and exercise methods for analyzing and interpreting xLPR v2.0 outputs ; and (iii) exercise the various sampling options available in xLPR v2.0. The simulation workflow template developed during the course of this effort helps to form a basis for the application ofmore » the xLPR code to problems with similar inputs and probabilistic requirements and address in a systematic manner the three points covered by the scope.« less
40 CFR 147.251 - EPA-administered program-Class I, III, IV and V wells and Indian lands.
Code of Federal Regulations, 2011 CFR
2011-07-01
..., IV and V wells and Indian lands. 147.251 Section 147.251 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS (CONTINUED) STATE, TRIBAL, AND EPA-ADMINISTERED UNDERGROUND INJECTION CONTROL PROGRAMS California § 147.251 EPA-administered program—Class I, III, IV and V wells and...
40 CFR 147.301 - EPA-administered program-Class I, III, IV, V wells and Indian lands.
Code of Federal Regulations, 2011 CFR
2011-07-01
..., IV, V wells and Indian lands. 147.301 Section 147.301 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS (CONTINUED) STATE, TRIBAL, AND EPA-ADMINISTERED UNDERGROUND INJECTION CONTROL PROGRAMS Colorado § 147.301 EPA-administered program—Class I, III, IV, V wells and Indian...
Youth Services Training Program 1972-1976: A Title III Project.
ERIC Educational Resources Information Center
Luskin, Bernice; And Others
Described is a Title III work study model to provide a 4-year vocational training program for approximately 40 handicapped junior and senior high school students in Westport, Connecticut. Program activities (such as conferences with employers) and the needed professional personnel (such as a school psychologist) are outlined for each of the…
25 CFR 36.12 - Standard III-Program needs assessment.
Code of Federal Regulations, 2013 CFR
2013-04-01
... 25 Indians 1 2013-04-01 2013-04-01 false Standard III-Program needs assessment. 36.12 Section 36... Management § 36.12 Standard III—Program needs assessment. The policy and procedures of each school and its curricula shall be developed and revised based on an assessment of educational needs. This needs assessment...
25 CFR 36.12 - Standard III-Program needs assessment.
Code of Federal Regulations, 2012 CFR
2012-04-01
... 25 Indians 1 2012-04-01 2011-04-01 true Standard III-Program needs assessment. 36.12 Section 36.12... § 36.12 Standard III—Program needs assessment. The policy and procedures of each school and its curricula shall be developed and revised based on an assessment of educational needs. This needs assessment...
25 CFR 36.12 - Standard III-Program needs assessment.
Code of Federal Regulations, 2011 CFR
2011-04-01
... 25 Indians 1 2011-04-01 2011-04-01 false Standard III-Program needs assessment. 36.12 Section 36... Management § 36.12 Standard III—Program needs assessment. The policy and procedures of each school and its curricula shall be developed and revised based on an assessment of educational needs. This needs assessment...
25 CFR 36.12 - Standard III-Program needs assessment.
Code of Federal Regulations, 2014 CFR
2014-04-01
... 25 Indians 1 2014-04-01 2014-04-01 false Standard III-Program needs assessment. 36.12 Section 36... Management § 36.12 Standard III—Program needs assessment. The policy and procedures of each school and its curricula shall be developed and revised based on an assessment of educational needs. This needs assessment...
40 CFR 147.251 - EPA-administered program-Class I, III, IV and V wells and Indian lands.
Code of Federal Regulations, 2010 CFR
2010-07-01
..., IV and V wells and Indian lands. 147.251 Section 147.251 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS (CONTINUED) STATE, TRIBAL, AND EPA-ADMINISTERED UNDERGROUND INJECTION CONTROL PROGRAMS California § 147.251 EPA-administered program—Class I, III, IV and V wells and...
40 CFR 147.301 - EPA-administered program-Class I, III, IV, V wells and Indian lands.
Code of Federal Regulations, 2010 CFR
2010-07-01
..., IV, V wells and Indian lands. 147.301 Section 147.301 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS (CONTINUED) STATE, TRIBAL, AND EPA-ADMINISTERED UNDERGROUND INJECTION CONTROL PROGRAMS Colorado § 147.301 EPA-administered program—Class I, III, IV, V wells and Indian...
Options for demonstrating the use of solar energy in california buildings
NASA Technical Reports Server (NTRS)
Davis, E. S.; Yanow, G.
1976-01-01
Three programmatic options for demonstrating the most economically attractive applications of solar energy to buildings located in California are formulated. The unique characteristics of solar energy demonstration programs and the involvement of key decision makers are discussed in detail. The demonstration programs are related to specific purposes. The priority structure used to select the generic projects making up each program is discussed in relationship to the purposes of the program. In addition, some implications of the nature of the demonstration program for management are outlined.
Brief 74 Nuclear Engineering Enrollments and Degrees Survey, 2014 Data
DOE Office of Scientific and Technical Information (OSTI.GOV)
None, None
2015-03-15
The 2014 survey includes degrees granted between September 1, 2013 and August 31, 2014, and enrollments for fall 2014. There are three academic programs new to this year's survey. Thirty-five academic programs reported having nuclear engineering programs during 2014, and data were provided by all thirty-five. The enrollments and degrees data include students majoring in nuclear engineering or in an option program equivalent to a major. Two nuclear engineering programs have indicated that health physics option enrollments and degrees are also reported in the health physics enrollments and degrees survey.
40 CFR 147.2200 - State-administered program-Class I, III, IV, and V wells.
Code of Federal Regulations, 2010 CFR
2010-07-01
... the in situ combustion of coal are regulated by the Rail Road Commission of Texas under a separate UIC... program for Class I, III, IV, and V wells in the State of Texas, except for those wells on Indian lands... (SDWA). Notice of the original approval for Class I, III, IV, and V wells was published in the Federal...
40 CFR 147.2200 - State-administered program-Class I, III, IV, and V wells.
Code of Federal Regulations, 2012 CFR
2012-07-01
... the in situ combustion of coal are regulated by the Rail Road Commission of Texas under a separate UIC... program for Class I, III, IV, and V wells in the State of Texas, except for those wells on Indian lands... (SDWA). Notice of the original approval for Class I, III, IV, and V wells was published in the Federal...
ERIC Educational Resources Information Center
American Chemical Society, Columbus, OH. Chemical Abstracts Service.
This Annual Report describes in detail the work performed during the first year of Task III of Contract NSF-C414 and the present status of Task III work. The programs and achievements described constitute the first significant efforts to develop a user-oriented, cooperative program between major secondary scientific and technical information…
40 CFR Appendix III to Part 1068 - High-Altitude Counties
Code of Federal Regulations, 2011 CFR
2011-07-01
... 40 Protection of Environment 33 2011-07-01 2011-07-01 false High-Altitude Counties III Appendix III to Part 1068 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR POLLUTION CONTROLS GENERAL COMPLIANCE PROVISIONS FOR ENGINE PROGRAMS Pt. 1068, App. III Appendix III to Part 1068...
40 CFR Appendix III to Part 1068 - High-Altitude Counties
Code of Federal Regulations, 2010 CFR
2010-07-01
... 40 Protection of Environment 32 2010-07-01 2010-07-01 false High-Altitude Counties III Appendix III to Part 1068 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR POLLUTION CONTROLS GENERAL COMPLIANCE PROVISIONS FOR ENGINE PROGRAMS Pt. 1068, App. III Appendix III to Part 1068...
The diet game. Weighing the options.
Lemaire, D.
1993-01-01
As a major source of nutrition information for the public, physicians have a responsibility to assist their patients to make safe choices about weight loss programs. While most diet programs result in weight loss, the "quick fix" potentially is harmful. This article describes weight control options and their strengths and weaknesses. PMID:8471909
Biomedical Engineering Education: A Conservative Approach
ERIC Educational Resources Information Center
Niemi, Eugene E., Jr.
1973-01-01
Describes the demand for graduates from biomedical engineering programs as being not yet fully able to absorb the supply. Suggests small schools interested in entering the field consider offering their programs at the undergraduate level via a minor or an option. Examples of such options and student projects are included. (CC)
45 CFR 1306.35 - Family child care program option.
Code of Federal Regulations, 2012 CFR
2012-10-01
... cognitive, socio-emotional, and physical development, including both gross and fine motor. Family child care... 45 Public Welfare 4 2012-10-01 2012-10-01 false Family child care program option. 1306.35 Section 1306.35 Public Welfare Regulations Relating to Public Welfare (Continued) OFFICE OF HUMAN DEVELOPMENT...
45 CFR 1306.35 - Family child care program option.
Code of Federal Regulations, 2014 CFR
2014-10-01
... cognitive, socio-emotional, and physical development, including both gross and fine motor. Family child care... 45 Public Welfare 4 2014-10-01 2014-10-01 false Family child care program option. 1306.35 Section 1306.35 Public Welfare Regulations Relating to Public Welfare (Continued) OFFICE OF HUMAN DEVELOPMENT...
45 CFR 1306.35 - Family child care program option.
Code of Federal Regulations, 2013 CFR
2013-10-01
... cognitive, socio-emotional, and physical development, including both gross and fine motor. Family child care... 45 Public Welfare 4 2013-10-01 2013-10-01 false Family child care program option. 1306.35 Section 1306.35 Public Welfare Regulations Relating to Public Welfare (Continued) OFFICE OF HUMAN DEVELOPMENT...
45 CFR 1306.35 - Family child care program option.
Code of Federal Regulations, 2011 CFR
2011-10-01
... cognitive, socio-emotional, and physical development, including both gross and fine motor. Family child care... 45 Public Welfare 4 2011-10-01 2011-10-01 false Family child care program option. 1306.35 Section 1306.35 Public Welfare Regulations Relating to Public Welfare (Continued) OFFICE OF HUMAN DEVELOPMENT...
41 CFR 102-194.25 - What is an automated Standard or Optional format?
Code of Federal Regulations, 2010 CFR
2010-07-01
... Property Management Regulations System (Continued) FEDERAL MANAGEMENT REGULATION ADMINISTRATIVE PROGRAMS 194-STANDARD AND OPTIONAL FORMS MANAGEMENT PROGRAM § 102-194.25 What is an automated Standard or... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false What is an automated...
ERIC Educational Resources Information Center
Poulsen, Joyce G.
This paper describes the Winnebago County (Wisconsin) Community Options Program, begun in January, 1982, which provides for a comprehensive assessment of all elderly persons within the target area who are at risk of becoming institutionalized. The paper focuses on the planning activities for the first year of the pilot program including community…
Expanding Educational Services for Adults. OPTIONS. Publicity Kit.
ERIC Educational Resources Information Center
Ohio State Univ., Columbus. National Center for Research in Vocational Education.
This publicity kit is intended to provide adult educators with materials for promoting and recruiting students into an adult education program designed according to the OPTIONS model (i.e., programs geared toward teaching the literacy, technical, and entrepreneurship skills that are necessary to adapt to changing labor market conditions resulting…
Garvelink, Mirjam Marjolein; Jones, C Allyson; Archambault, Patrick M; Roy, Noémie; Blair, Louisa
2017-01-01
Background Seniors with loss of autonomy may face decisions about whether they should stay at home or move elsewhere. Most seniors would prefer to stay home and be independent for as long as possible, but most are unaware of options that would make this possible. Objective The study aimed to develop and test the acceptability of an interactive website for seniors, their caregivers, and health professionals with short interlinked videos presenting information about options for staying independent at home. Methods The approach for design and data collection varied, involving a multipronged, user-centered design of the development process, qualitative interviews, and end-user feedback to determine content (ie, needs assessment) in phase I; module development (in English and French) in phase II; and survey to test usability and acceptability with end users in phase III. Phase I participants were a convenience sample of end users, that is, seniors, caregivers, and professionals with expertise in modifiable factors (eg, day centers, home redesign, equipment, community activities, and finances), enabling seniors to stay independent at home for longer in Quebec and Alberta, Canada. Phase II participants were bilingual actors; phase III participants included phase I participants and new participants recruited through snowballing. Qualitative interviews were thematically analyzed in phase II to determine relevant topics for the video-scripts, which were user-checked by interview participants. In phase III, the results of a usability questionnaire were analyzed using descriptive statistics. Results In phase I, interviews with 29 stakeholders, including 4 seniors, 3 caregivers, and 22 professionals, showed a need for a one-stop information resource about options for staying independent at home. They raised issues relating to 6 categories: cognitive autonomy, psychological or mental well-being, functional autonomy, social autonomy, financial autonomy, and people involved. A script was developed and evaluated by participants. In phase II, after 4 days in a studio with 15 bilingual actors, 30 videos were made of various experts (eg, family doctor, home care nurse, and social worker) presenting options and guidance for the decision-making process. These were integrated into an interactive website, which included a comments tool for visitors to add information. In phase III (n=21), 8 seniors (7 women, mean age 75 years), 7 caregivers, and 6 professionals evaluated the acceptability of the module and suggested improvements. Clarity of the videos scored 3.6 out of 4, length was considered right by 17 (separate videos) and 13 participants (all videos together), and 18 participants considered the module acceptable. They suggested that information should be tailored more, and that seniors may need someone to help navigate it. Conclusions Our interactive website with interlinked videos presenting information about options for staying independent at home was deemed acceptable and potentially helpful by a diverse group of stakeholders. PMID:29242178
21 CFR 145.175 - Canned pears.
Code of Federal Regulations, 2010 CFR
2010-04-01
... optional ingredients. (i) Natural and artificial flavors. (ii) Spice. (iii) Vinegar, lemon juice, or... characterizes the product as specified in § 101.22 of this chapter and a declaration of any spice or seasoning that characterizes the product; for example, “Spice added”, or in lieu of the word “Spice”, the common...
7 CFR 1468.4 - Establishing Conservation Farm Option (CFO) pilot project areas.
Code of Federal Regulations, 2014 CFR
2014-01-01
...) Conservation of soil, water, and related natural resources, (ii) Water quality protection or improvement, (iii) Wetland restoration and protection, and (iv) Wildlife habitat development and protection, (v) Or other... production flexibility contract, which is authorized by the Agricultural Marketing and Transition Act of 1996...
7 CFR 1468.4 - Establishing Conservation Farm Option (CFO) pilot project areas.
Code of Federal Regulations, 2012 CFR
2012-01-01
...) Conservation of soil, water, and related natural resources, (ii) Water quality protection or improvement, (iii) Wetland restoration and protection, and (iv) Wildlife habitat development and protection, (v) Or other... production flexibility contract, which is authorized by the Agricultural Marketing and Transition Act of 1996...
7 CFR 1468.4 - Establishing Conservation Farm Option (CFO) pilot project areas.
Code of Federal Regulations, 2013 CFR
2013-01-01
...) Conservation of soil, water, and related natural resources, (ii) Water quality protection or improvement, (iii) Wetland restoration and protection, and (iv) Wildlife habitat development and protection, (v) Or other... production flexibility contract, which is authorized by the Agricultural Marketing and Transition Act of 1996...
40 CFR 89.102 - Effective dates, optional inclusion, flexibility for equipment manufacturers.
Code of Federal Regulations, 2010 CFR
2010-07-01
... exemptions for technical or engineering hardship. You may request additional engine allowances under... technical or engineering problems that prevent you from meeting the requirements of this part. You must show... your engine supplier to design products. (iii) Describe the engineering or technical problems causing...
Code of Federal Regulations, 2014 CFR
2014-10-01
... agency imposes cost sharing under § 447.54, the process by which hospital emergency room services are... State option, cost sharing imposed for any service (other than for drugs and non-emergency services... group under § 447.56(a), and (iii) For cost sharing imposed for non-emergency services furnished in an...
40 CFR 89.102 - Effective dates, optional inclusion, flexibility for equipment manufacturers.
Code of Federal Regulations, 2013 CFR
2013-07-01
... exemptions for technical or engineering hardship. You may request additional engine allowances under... technical or engineering problems that prevent you from meeting the requirements of this part. You must show... your engine supplier to design products. (iii) Describe the engineering or technical problems causing...
40 CFR 89.102 - Effective dates, optional inclusion, flexibility for equipment manufacturers.
Code of Federal Regulations, 2012 CFR
2012-07-01
... exemptions for technical or engineering hardship. You may request additional engine allowances under... technical or engineering problems that prevent you from meeting the requirements of this part. You must show... your engine supplier to design products. (iii) Describe the engineering or technical problems causing...
Reframing Reality: Christmas at the Mall.
ERIC Educational Resources Information Center
Long, Nicholas J.; Daniels, Doug
1993-01-01
Presents Life Space Interview (LSI), effective intervention strategy for use during crisis work with troubled students, as it was applied to case of eight-year-old boy attending Option III class for emotionally handicapped students when he accompanied class to mall for holiday shopping trip. Following interview are instructional comments on the…
77 FR 67269 - Voluntary Licensing of Amateur Rocket Operations; Withdrawal
Federal Register 2010, 2011, 2012, 2013, 2014
2012-11-09
...-0318; Amdt. No. 400-4] RIN 2120-AK16 Voluntary Licensing of Amateur Rocket Operations; Withdrawal... that conduct certain amateur rocket launches to voluntarily apply for a commercial space transportation... give operators of Class 3 advanced high-power rockets the option of applying for a chapter III launch...
75 FR 3941 - Notice of Information Collection
Federal Register 2010, 2011, 2012, 2013, 2014
2010-01-25
... collection and analysis of worldwide safety issues. II. Method of Collection Aviation stakeholders will be... option of printing it and filling it out manually and then returning it via traditional mail, filling it.... III. Data Title: Biennial NextGen Safety Issue Survey. OMB Number: 2700-XXXX. Type of Review: New...
Huber, J; Pötsch, B; Gantschacher, M; Templ, M
2016-10-01
Introduction: Diagnosis and treatment of vaginal and cervical cytological cell changes are described in European and national guidelines. The aim of this data collection was to evaluate the remission rates of PAP III and PAP III D cytological findings in patients over a period of 3-4 months. Method: The current state of affairs in managing suspicious and cytological findings (PAP III, and III D) in gynecological practice was assessed in the context of a data collection survey. An evaluation over a period of 24 months was conducted on preventative measures, the occurrence and changes to normal/suspect/pathological findings and therapy management (for suspicious or pathological findings). Results: 307 female patients were included in the analysis. At the time of the survey 186 patients (60.6 %) had PAP III and 119 (38.8 %) had PAP III D findings. The spontaneous remission rate of untreated PAP III patients was 6 % and that of untreated PAP III D patients was 11 %. The remission rates of patients treated with a vaginal gel were 77 % for PAP III and 71 % for PAP III D. Conclusion: A new treatment option was used in gynecological practice on patients with PAP III and PAP III D findings between confirmation and the next follow-up with excellent success.
Navy CG(X) Cruiser Program: Background, Oversight Issues, and Options for Congress
2009-11-20
and Options for Congress 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e . TASK NUMBER 5f. WORK...Another press report (Katherine McIntire Peters, “Navy’s Top Officer Sees Lessons in Shipbuilding Program Failures,” GovernmentExecutive.com, September...whether the schedule for procuring CG(X)s is properly aligned with foreign-country ballistic missile development programs. A 2005 defense trade
Navy CG(X) Cruiser Program: Background, Oversight Issues, and Options for Congress
2009-10-21
and Options for Congress 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e . TASK NUMBER 5f. WORK...Navy’s Top Officer Sees Lessons in Shipbuilding Program Failures,” GovernmentExecutive.com, September 24, 2008) quoted Admiral Gary Roughead, the...related question is whether the schedule for procuring CG(X)s is properly aligned with foreign-country ballistic missile development programs. A 2005
NASA Technical Reports Server (NTRS)
Collins, L.; Saunders, D.
1986-01-01
User information for program PROFILE, an aerodynamics design utility for refining, plotting, and tabulating airfoil profiles is provided. The theory and implementation details for two of the more complex options are also presented. These are the REFINE option, for smoothing curvature in selected regions while retaining or seeking some specified thickness ratio, and the OPTIMIZE option, which seeks a specified curvature distribution. REFINE uses linear techniques to manipulate ordinates via the central difference approximation to second derivatives, while OPTIMIZE works directly with curvature using nonlinear least squares techniques. Use of programs QPLOT and BPLOT is also described, since all of the plots provided by PROFILE (airfoil coordinates, curvature distributions) are achieved via the general purpose QPLOT utility. BPLOT illustrates (again, via QPLOT) the shape functions used by two of PROFILE's options. The programs were designed and implemented for the Applied Aerodynamics Branch at NASA Ames Research Center, Moffett Field, California, and written in FORTRAN and run on a VAX-11/780 under VMS.
ERIC Educational Resources Information Center
National Public Radio, Washington, DC.
This booklet is a transcription of a program from the radio series, "Options in Education." It is part 2 of a two-part series dealing with sexism in education. It deals with sex discrimination in various aspects of public education, including textbooks, teacher promotion, sports programs and children's literature. There is also a…
Recent updates of precision therapy for gastric cancer: Towards optimal tailored management.
Joo, Moon Kyung; Park, Jong-Jae; Chun, Hoon Jai
2016-05-21
Signaling pathways of gastric carcinogenesis and gastric cancer progression are being avidly studied to seek optimal treatment of gastric cancer. Among them, hepatocyte growth factor (HGF)/c-MET, phosphoinositide 3-kinase (PI3K)/Akt/mammalian target of rapamycin (mTOR) and janus kinase 2/signal transducer and activator of transcription 3 (JAK2/STAT3) pathways have been widely investigated. Their aberrant expression or mutation has been significantly associated with advanced stage or poor prognosis of gastric cancer. Recently, aberrations of immune checkpoints including programmed cell death-1/programmed cell death ligand-1 (PD-1/PD-L1) have been suggested as an important step in the formation of a microenvironment favorable for gastric cancer. Accomplishments in basic research have led to the development of novel agents targeting these signaling pathways. However, phase III studies of selective anti-HGF/c-MET antibodies and mTOR inhibitor failed to show significant benefits in terms of overall survival and progression-free survival. Few agents directly targeting STAT3 have been developed. However, this target is still critical issue in terms of chemoresistance, and SH2-containing protein tyrosine phosphatase 1 might be a significant link to effectively inhibit STAT3 activity. Inhibition of PD-1/PD-L1 showed durable efficacy in phase I studies, and phase III evaluation is warranted. Therapeutic strategy to concurrently inhibit multiple tyrosine kinases is a reasonable option, however, lapatinib needs to be further evaluated to identify good responders. Regorafenib has shown promising effectiveness in prolonging progression-free survival in a phase II study. In this topic highlight, we review the biologic roles and outcomes of clinical studies targeting these signaling pathways.
Singh, Ashbindu; Shi, Hua; Foresman, T.; Fosnight, Eugene A.
2001-01-01
Historically, it appears that some of the WRCF have survived because i) they lack sufficient quantity of commercially valuable species; ii) they are located in remote or inaccessible areas; or iii) they have been protected as national parks and sanctuaries. Forests will be protected when people who are deciding the fate of forests conclude than the conservation of forests is more beneficial, e.g. generates higher incomes or has cultural or social values, than their clearance. If this is not the case, forests will continue to be cleared and converted. In the future, the WRCF may be protected only by focused attention. The future policy options may include strategies for strong protection measures, the raising of public awareness about the value of forests, and concerted actions for reducing pressure on forest lands by providing alternatives to forest exploitation to meet the growing demands of forest products. Many areas with low population densities offer an opportunity for conservation if appropriate steps are taken now by the national governments and international community. This opportunity must be founded upon the increased public and government awareness that forests have vast importance to the welfare of humans and ecosystems' services such as biodiversity, watershed protection, and carbon balance. Also paramount to this opportunity is the increased scientific understanding of forest dynamics and technical capability to install global observation and assessment systems. High-resolution satellite data such as Landsat 7 and other technologically advanced satellite programs will provide unprecedented monitoring options for governing authorities. Technological innovation can contribute to the way forests are protected. The use of satellite imagery for regular monitoring and Internet for information dissemination provide effective tools for raising worldwide awareness about the significance of forests and intrinsic value of nature.
Maclayton, Darego O; Hall, Ronald G
2007-02-01
To discuss current and potential treatment options for nosocomial pneumonia due to methicillin-resistant Staphylococcus aureus (MRSA). A MEDLINE search (1966-January 2007) was conducted to identify English-language literature on pharmacotherapy of nosocomial pneumonia and the bibliographies of pertinent articles. Programs and abstracts from infectious disease meetings were also searched. Search terms included MRSA, nosocomial pneumonia, pulmonary infections, vancomycin, quinupristin/dalfopristin, linezolid, daptomycin, tigecycline, dalbavancin, oritavancin, and ceftobiprole. DATA SELECTION AND DATA EXTRACTION: All articles were critically evaluated and all pertinent information was included in this review. Vancomycin has been the drug of choice for MRSA infections for many years. Recent data suggest that linezolid may be superior to vancomycin in the treatment of MRSA nosocomial pneumonia. However, there are limitations to the available data. Therefore, prospective, randomized studies are needed before linezolid is recommended as the preferred first-line therapy. Other approved agents for nosocomial MRSA infections, such as quinupristin/dalfopristin and daptomycin, should not be used in the treatment of MRSA pneumonia, as they were inferior in clinical trials. Tigecycline has excellent activity against MRSA in vitro, but should not be routinely used for the treatment of MRSA pneumonia, as clinical data are lacking. In a Phase III clinical trial, an anti-MRSA cephalosporin, ceftobiprole, is being evaluated for effectiveness against nosocomial pneumonia. Investigational glycopeptides may eventually have a role in the treatment of nosocomial pneumonia, but data are currently lacking. Vancomycin is still the drug of choice for treatment of MRSA pneumonia, and linezolid should be used as an alternative agent. Linezolid should carry strong consideration for patients with vancomycin-induced nephrotoxicity or a documented lack of response to vancomycin. Tigecycline and investigational agents with activity against MRSA may be future options for nosocomial pneumonia due to MRSA.
Farooqui, Muhammad Assad; Tan, Yock-Theng; Bilger, Marcel; Finkelstein, Eric A
2014-02-10
There is extensive evidence that regular physical activity confers numerous health benefits. Despite this, high rates of physical inactivity prevail among older adults. This study aimed to ascertain if incentives could be effective in motivating physical activity through improving uptake of walking programs, either with or without an enrolment fee to cover corresponding costs. A discrete-choice conjoint survey was fielded to a national sample of older adults in Singapore. Each respondent was given ten pairs of hypothetical walking programs and asked to choose the option they preferred. Each option varied along several dimensions, including the level and type (cash, voucher, or health savings credit) of incentive and an enrolment fee. For each option, they were asked how likely they would be to join their preferred program. A random utility model (RUM) was used to analyze the responses. Results suggest that a free 6-month program with a $500 cash incentive would generate enrolment rates of 58.5%; charging $50 to enroll lowers this to 55.7%. In terms of incentive type, cash payments were the most preferred incentive but not significantly different from supermarket vouchers. Both were preferred to health savings credits and sporting goods vouchers. Concerns of adverse selection were minimal because those who were inactive represented at least 72% of new participants for any offered program(s) and were the majority. Study results demonstrate the potential for even modest incentives to increase program uptake among inactive older adults. Moreover, although cash was the most preferred option, supermarket vouchers, which could potentially be purchased at a discount, were a close alternative. Results also suggest that an enrolment fee is a viable option to offset the costs of incentives as it has only minimal impact on participation.
34 CFR 299.2 - What general administrative regulations apply to ESEA programs?
Code of Federal Regulations, 2010 CFR
2010-07-01
... programs under title III of the Goals 2000: Educate America Act (title III of Goals 2000), unless a State...). Note: To meet the first of the three standards, alternative State provisions must, among other things...
24 CFR 982.630 - Homeownership option: Homeownership counseling.
Code of Federal Regulations, 2013 CFR
2013-04-01
... counseling. 982.630 Section 982.630 Housing and Urban Development REGULATIONS RELATING TO HOUSING AND URBAN... Types Homeownership Option § 982.630 Homeownership option: Homeownership counseling. (a) Before... pre-assistance homeownership and housing counseling program required by the PHA (pre-assistance...
24 CFR 982.630 - Homeownership option: Homeownership counseling.
Code of Federal Regulations, 2012 CFR
2012-04-01
... counseling. 982.630 Section 982.630 Housing and Urban Development REGULATIONS RELATING TO HOUSING AND URBAN... Types Homeownership Option § 982.630 Homeownership option: Homeownership counseling. (a) Before... pre-assistance homeownership and housing counseling program required by the PHA (pre-assistance...
24 CFR 982.630 - Homeownership option: Homeownership counseling.
Code of Federal Regulations, 2014 CFR
2014-04-01
... counseling. 982.630 Section 982.630 Housing and Urban Development REGULATIONS RELATING TO HOUSING AND URBAN... Types Homeownership Option § 982.630 Homeownership option: Homeownership counseling. (a) Before... pre-assistance homeownership and housing counseling program required by the PHA (pre-assistance...
24 CFR 982.630 - Homeownership option: Homeownership counseling.
Code of Federal Regulations, 2011 CFR
2011-04-01
... counseling. 982.630 Section 982.630 Housing and Urban Development REGULATIONS RELATING TO HOUSING AND URBAN... Types Homeownership Option § 982.630 Homeownership option: Homeownership counseling. (a) Before... pre-assistance homeownership and housing counseling program required by the PHA (pre-assistance...
24 CFR 982.630 - Homeownership option: Homeownership counseling.
Code of Federal Regulations, 2010 CFR
2010-04-01
... counseling. 982.630 Section 982.630 Housing and Urban Development Regulations Relating to Housing and Urban... Types Homeownership Option § 982.630 Homeownership option: Homeownership counseling. (a) Before... pre-assistance homeownership and housing counseling program required by the PHA (pre-assistance...
Elit, Laurie; Jimenez, Waldo; McAlpine, Jessica; Ghatage, Prafull; Miller, Dianne; Plante, Marie
2011-03-01
To help care providers understand the current status of cervical cancer in low-resource countries. The most effective and practical options for cervical screening and treatment in low-resource countries are evaluated. Improvement in rates of prevention and early detection of cervical cancer in low-resource countries. PubMed or Medline, CINAHL, and The Cochrane Library were searched for studies published in English between January 2006 and December 2009. Results were restricted to systematic reviews, randomized control trials/controlled clinical trials, and observational studies. Grey (unpublished) literature was identified through searching the websites of health technology assessment and health technology assessment-related agencies, clinical practice guideline collections, clinical trial registries, and national and international medical specialty societies. The quality of evidence was rated using the criteria described in the Report of the Canadian Task Force on Preventive Health Care. Recommendations for practice were ranked according to the method described in that report (Table). RECOMMENDATIONS 1. All girls 9 years old or over should have access to the cervical cancer vaccine before they become sexually active. (I-A) 2. Cervical cancer screening by visual inspection with acetic acid is suggested for low-resource settings acceptable. Cervical cytology or human papillomavirus testing may also be used when practical. (II-2B) 3. Cryotherapy is a safe, effective, and low-cost therapy that should be included in pre-invasive cervical cancer treatment. (III-B) 4. All countries should have a documented cervical cancer prevention strategy that includes public education built on existing outreach programs. (III-C) 5. Countries should define a centre or centres of excellence for the management of cervical cancer. (III-C) Because these units would serve a larger population, they would be able to identify leaders and develop their skills, and would be able to invest in costly radiation equipment. 6. All women with cervical cancer should have access to pain management. (III-C).
Federal Register 2010, 2011, 2012, 2013, 2014
2012-12-11
...-Regulatory Organizations; BOX Options Exchange LLC; Notice of Filing and Immediate Effectiveness of a Proposal To Expand the Short Term Options Series Program December 5, 2012. Pursuant to Section 19(b)(1) of... that, on December 4, 2012, BOX Options Exchange LLC (the ``Exchange'') filed with the Securities and...
2018-01-01
Abstract Dopamine has been suggested to be crucially involved in effort-related choices. Key findings are that dopamine depletion (i) changed preference for a high-cost, large-reward option to a low-cost, small-reward option, (ii) but not when the large-reward option was also low-cost or the small-reward option gave no reward, (iii) while increasing the latency in all the cases but only transiently, and (iv) that antagonism of either dopamine D1 or D2 receptors also specifically impaired selection of the high-cost, large-reward option. The underlying neural circuit mechanisms remain unclear. Here we show that findings i–iii can be explained by the dopaminergic representation of temporal-difference reward-prediction error (TD-RPE), whose mechanisms have now become clarified, if (1) the synaptic strengths storing the values of actions mildly decay in time and (2) the obtained-reward-representing excitatory input to dopamine neurons increases after dopamine depletion. The former is potentially caused by background neural activity–induced weak synaptic plasticity, and the latter is assumed to occur through post-depletion increase of neural activity in the pedunculopontine nucleus, where neurons representing obtained reward exist and presumably send excitatory projections to dopamine neurons. We further show that finding iv, which is nontrivial given the suggested distinct functions of the D1 and D2 corticostriatal pathways, can also be explained if we additionally assume a proposed mechanism of TD-RPE calculation, in which the D1 and D2 pathways encode the values of actions with a temporal difference. These results suggest a possible circuit mechanism for the involvements of dopamine in effort-related choices and, simultaneously, provide implications for the mechanisms of TD-RPE calculation. PMID:29468191
NASA Technical Reports Server (NTRS)
Fortenbaugh, R. L.
1980-01-01
Instructions for using Vertical Attitude Takeoff and Landing Aircraft Simulation (VATLAS), the digital simulation program for application to vertical attitude takeoff and landing (VATOL) aircraft developed for installation on the NASA Ames CDC 7600 computer system are described. The framework for VATLAS is the Off-Line Simulation (OLSIM) routine. The OLSIM routine provides a flexible framework and standardized modules which facilitate the development of off-line aircraft simulations. OLSIM runs under the control of VTOLTH, the main program, which calls the proper modules for executing user specified options. These options include trim, stability derivative calculation, time history generation, and various input-output options.
NASA Technical Reports Server (NTRS)
Nakazawa, Shohei
1989-01-01
The user options available for running the MHOST finite element analysis package is described. MHOST is a solid and structural analysis program based on the mixed finite element technology, and is specifically designed for 3-D inelastic analysis. A family of 2- and 3-D continuum elements along with beam and shell structural elements can be utilized, many options are available in the constitutive equation library, the solution algorithms and the analysis capabilities. The outline of solution algorithms is discussed along with the data input and output, analysis options including the user subroutines and the definition of the finite elements implemented in the program package.
A Second Year Evaluation of the ESEA Title III Urban Leadership Program.
ERIC Educational Resources Information Center
Frerichs, Allen H.
The Urban Leadership Program, funded under Title III of the Elementary and Secondary Education Act, was carried out among sixth graders at the Albert Einstein School in Chicago, Illinois. The primary purpose of the program was to develop skills and competence to prepare participants for survival and success in a large urban environment. A…
Oregon Small Schools Program: A Title III Project. Independent Evaluation Report, 1972.
ERIC Educational Resources Information Center
Miller, Donald F.
An Elementary and Secondary Education Act (ESEA) Title III project, the 1971-72 Oregon Small Schools Program (OSSP) objectives were (1) to increase member schools receptivity to new and better ideas in education; (2) to implement new programs and apply new techniques consistent with the Oregon Board of Education priority objectives and with the…
ERIC Educational Resources Information Center
Boyle, E.; Carlson, K.
Volume III of a study of the Education Professions Development Act (EPDA) training programs for higher education personnel presents the second of a three-faceted approach to assess current needs. This document reviews the task of profiling EPDA V-E training programs to produce a small-scale information system. Section one reviews the profiling…
Rothschild, Uta; Muller, Laurent; Lechner, Axel; Schlösser, Hans A; Beutner, Dirk; Läubli, Heinz; Zippelius, Alfred; Rothschild, Sacha I
2018-05-14
Head and neck squamous cell carcinoma (HNSCC) is a frequent tumour arising from multiple anatomical subsites in the head and neck region. The treatment for early-stage disease is generally single modality, either surgery or radiotherapy. The treatment for locally advanced tumours is multimodal. For recurrent/metastatic HNSCC palliative chemotherapy is standard of care. The prognosis is limited and novel treatment approaches are urgently needed. HNSCC evades immune responses through multiple resistance mechanisms. HNSCC is particularly characterised by an immunosuppressive environment which includes the release of immunosuppressive factors, activation, expansion of immune cells with inhibitory activity and decreased tumour immunogenicity. An in-depth understanding of these mechanisms led to rational design of immunotherapeutic approaches and clinical trials. Currently, only immune checkpoint inhibitors, namely monoclonal antibodies targeting the immune inhibitory receptor programmed cell death 1 (PD-1) and its ligand PD-L1 have proven clinical efficacy in randomised phase III trials. The PD-1 inhibitor nivolumab is the only drug approved for platinum-refractory recurrent/metastatic HNSCC. However, many more immunotherapeutic treatment options are currently under investigation. Ongoing trials are investigating immunotherapeutic approaches also in the curative setting and combination therapies using different immunotherapeutic approaches. This review article summarises current knowledge of the role of the immune system in the development and progression of HNSCC, and provides a comprehensive overview on the development of immunotherapeutic approaches.
78 FR 77365 - Federal Employees' Group Life Insurance Program: Options B and C
Federal Register 2010, 2011, 2012, 2013, 2014
2013-12-23
... 3206-AM96 Federal Employees' Group Life Insurance Program: Options B and C AGENCY: U.S. Office of... proposing to amend the Federal Employees' Group Life Insurance (FEGLI) regulations to provide an election... into law. This law, the Federal Employees Life Insurance Improvement Act, changed many parts of the...
45 CFR 1306.32 - Center-based program option.
Code of Federal Regulations, 2011 CFR
2011-10-01
... Center-based program option. (a) Class size. (1) Head Start classes must be staffed by a teacher and an aide or two teachers and, whenever possible, a volunteer. (2) Grantees must determine their class size based on the predominant age of the children who will participate in the class and whether or not a...
42 CFR 422.105 - Special rules for self-referral and point of service option.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 42 Public Health 3 2010-10-01 2010-10-01 false Special rules for self-referral and point of service option. 422.105 Section 422.105 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICARE PROGRAM MEDICARE ADVANTAGE PROGRAM Benefits and...
Social Media in Diabetes Education: A Viable Option?
ERIC Educational Resources Information Center
Cooper, Julie; Cox, Jill N.; Corbin, Marilyn A.
2012-01-01
As Extension educators are encouraged to implement more cost-effective and efficient means of programming, the use of Web-based social media has become a popular option. Penn State Extension implemented a social media awareness survey among participants in its community-based diabetes education program to determine familiarity with this medium,…
Code of Federal Regulations, 2010 CFR
2010-07-01
... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false For what Standard or... Contracts and Property Management Federal Property Management Regulations System (Continued) FEDERAL MANAGEMENT REGULATION ADMINISTRATIVE PROGRAMS 194-STANDARD AND OPTIONAL FORMS MANAGEMENT PROGRAM § 102-194.40...
EPA is evaluating ecosystem restoration and management techniques to ensure they create sustainable solutions for degraded watersheds. ORD NRMRL initiated the Restoration Plus (RePlus) program in 2002 to a) evaluate ecosystem restoration and management options, b) assess the non-...
Federal Register 2010, 2011, 2012, 2013, 2014
2012-03-05
... (``PFOF'') program that helps its Specialists \\5\\ and Directed Registered Options Traders [[Page 13163... flow provider directing some or all of its order flow to that Specialist or Directed ROT. This program is funded through fees paid by Registered Options Traders (``ROTs''), Specialists and Directed ROTs...
Space industrialization. Volume 3: Space industrialization implementation concepts
NASA Technical Reports Server (NTRS)
1978-01-01
Methods for selecting the most viable program options were examined along with techniques for hardware development. Several separate program options were defined, and future plans for space exploitation were reviewed. Hardware elements in various sectors of space are discussed in detail to provide a definition for the major functional elements and operations.
Options in Education, Transcript: Fantasy Magazine, Program No. 33.
ERIC Educational Resources Information Center
George Washington Univ., Washington, DC. Inst. for Educational Leadership.
"Options in Education" is a radio news program which focuses on issues and developments in education. This transcript contains discussions with Bruno Bettelheim on the importance of fairy tales for children, with Frank Williams on tensions in children when they try to create, and with Donald Bigelow on "Loudmouse" by Richard…
This document is the final report for EPA's Mine WAste Technology Program (MWTP) Activity III, Project 20--Selenium Treatment/Removal Alternatives Demonstration project. Selenium contamination originates from many sources including mining operations, mineral processing, abandoned...
IMP: Interactive mass properties program. Volume 1: Program description
NASA Technical Reports Server (NTRS)
Stewart, W. A.
1976-01-01
A method of computing a weights and center of gravity analysis of a flight vehicle using interactive graphical capabilities of the Adage 340 computer is described. The equations used to calculate area, volume, and mass properties are based on elemental surface characteristics. The input/output methods employ the graphic support of the Adage computer. Several interactive program options are available for analyzing the mass properties of a vehicle. These options are explained.
Rattanavipapong, Waranya; Anothaisintawee, Thunyarat; Teerawattananon, Yot
2018-01-01
Thailand is encountering challenges to introduce the high-cost sofosbuvir for chronic hepatitis C treatment as part of the Universal Health Care's benefit package. This study was conducted in respond to policy demand from the Thai government to assess the value for money and budget impact of introducing sofosbuvir-based regimens in the tax-based health insurance scheme. The Markov model was constructed to assess costs and benefits of the four treatment options that include: (i) current practice-peginterferon alfa (PEG) and ribavirin (RBV) for 24 weeks in genotype 3 and 48 weeks for other genotypes; (ii) Sofosbuvir plus peginterferon alfa and ribavirin (SOF+PEG-RBV) for 12 weeks; (iii) Sofosbuvir and daclatasvir (SOF+DCV) for 12 weeks; (iv) Sofosbuvir and ledipasvir (SOF+LDV) for 12 weeks for non-3 genotypes and SOF+PEG-RBV for 12 weeks for genotype 3 infection. Given that policy options (ii) and (iii) are for pan-genotypic infection, the cost of genotype testing was applied only for policy options (i) and (iv). Results reveal that all sofosbuvir-based regimens had greater quality adjusted life years (QALY) gains compared with the current treatment, therefore associated with lower lifetime costs and more favourable health outcomes. Additionally, among the three regimens of sofosbuvir, SOF+PEG-RBV for genotype 3 and SOF+LDV for non-3 genotype are the most cost-effective treatment option with the threshold of 160,000 THB per QALY gained. The results of this study had been used in policy discussion which resulted in the recent inclusion of SOF+PEG-RBV for genotype 3 and SOF+LDV for non-3 genotype in the Thailand's benefit package.
Process mining in oncology using the MIMIC-III dataset
NASA Astrophysics Data System (ADS)
Prima Kurniati, Angelina; Hall, Geoff; Hogg, David; Johnson, Owen
2018-03-01
Process mining is a data analytics approach to discover and analyse process models based on the real activities captured in information systems. There is a growing body of literature on process mining in healthcare, including oncology, the study of cancer. In earlier work we found 37 peer-reviewed papers describing process mining research in oncology with a regular complaint being the limited availability and accessibility of datasets with suitable information for process mining. Publicly available datasets are one option and this paper describes the potential to use MIMIC-III, for process mining in oncology. MIMIC-III is a large open access dataset of de-identified patient records. There are 134 publications listed as using the MIMIC dataset, but none of them have used process mining. The MIMIC-III dataset has 16 event tables which are potentially useful for process mining and this paper demonstrates the opportunities to use MIMIC-III for process mining in oncology. Our research applied the L* lifecycle method to provide a worked example showing how process mining can be used to analyse cancer pathways. The results and data quality limitations are discussed along with opportunities for further work and reflection on the value of MIMIC-III for reproducible process mining research.
Code of Federal Regulations, 2010 CFR
2010-07-01
... Implementation Plan Revisions Concerning CAIR SO2 Opt-In Units A Appendix A to Subpart III of Part 97 Protection... BUDGET TRADING PROGRAM AND CAIR NOX AND SO2 TRADING PROGRAMS CAIR SO2 Opt-in Units Pt. 97, Subpt. III... Concerning CAIR SO2 Opt-In Units 1. The following States have State Implementation Plan revisions under § 51...
Swertz, Morris A; De Brock, E O; Van Hijum, Sacha A F T; De Jong, Anne; Buist, Girbe; Baerends, Richard J S; Kok, Jan; Kuipers, Oscar P; Jansen, Ritsert C
2004-09-01
Genomic research laboratories need adequate infrastructure to support management of their data production and research workflow. But what makes infrastructure adequate? A lack of appropriate criteria makes any decision on buying or developing a system difficult. Here, we report on the decision process for the case of a molecular genetics group establishing a microarray laboratory. Five typical requirements for experimental genomics database systems were identified: (i) evolution ability to keep up with the fast developing genomics field; (ii) a suitable data model to deal with local diversity; (iii) suitable storage of data files in the system; (iv) easy exchange with other software; and (v) low maintenance costs. The computer scientists and the researchers of the local microarray laboratory considered alternative solutions for these five requirements and chose the following options: (i) use of automatic code generation; (ii) a customized data model based on standards; (iii) storage of datasets as black boxes instead of decomposing them in database tables; (iv) loosely linking to other programs for improved flexibility; and (v) a low-maintenance web-based user interface. Our team evaluated existing microarray databases and then decided to build a new system, Molecular Genetics Information System (MOLGENIS), implemented using code generation in a period of three months. This case can provide valuable insights and lessons to both software developers and a user community embarking on large-scale genomic projects. http://www.molgenis.nl
International Space Programs. Aerospace Education III.
ERIC Educational Resources Information Center
Air Univ., Maxwell AFB, AL. Junior Reserve Office Training Corps.
This curriculum guide is prepared for the Aerospace Education III series publication entitled "International Space Programs." The guide is organized according to specific chapters in the textbook. It provides guidelines for teachers in terms of objectives, behavioral objectives, suggested outlines, orientation, suggested key points,…
Lonardi, S; Sobrero, A; Rosati, G; Di Bartolomeo, M; Ronzoni, M; Aprile, G; Massida, B; Scartozzi, M; Banzi, M; Zampino, M G; Pasini, F; Marchetti, P; Cantore, M; Zaniboni, A; Rimassa, L; Ciuffreda, L; Ferrari, D; Barni, S; Zagonel, V; Maiello, E; Rulli, E; Labianca, R
2016-11-01
Six months of oxaliplatin-based adjuvant chemotherapy is standard of care for radically resected stage III colon cancer and an accepted option for high-risk stage II. A shorter duration of therapy, if equally efficacious, would be advantageous for patients and Health-Care Systems. TOSCA ['Randomized trial investigating the role of FOLFOX-4 or XELOX (3 versus 6 months) regimen duration and bevacizumab as adjuvant therapy for patients with stage II/III colon cancer] is an open-label, phase III, multicenter, noninferiority trial randomizing patients with high-risk stage II or stage III radically resected colon cancer to receive 3 months (arm 3 m) versus 6 months (arm 6 m) of FOLFOX4/XELOX. Primary end-point was relapse-free survival. We present here safety and compliance data. From June 2007 to March 2013, 3759 patients were accrued from 130 Italian sites, 64% receiving FOLFOX4 and 36% XELOX in either arm. Treatment completion rate without any modification was 35% versus 12% and with delays or dose reduction 52% versus 44% in arm 3 and 6 m. Treatment was permanently discontinued in 8% (arm 3 m) and 33% (arm 6 m). In arm 6 m, 50% of patients discontinuing treatment did so after completing 80% of planned program. Grade 3+ toxicities were higher in arm 6 m than that in 3 m. Grade 2+ neuropathy was 31.2% versus 8.8% (P < 0.0001) while grade 3+ was 8.4 versus 1.3 (P < 0.0001), in arm 3 and 6 m. Seven deaths within 30 days from last treatment administration in arm 6 m and three deaths in arm 3 m were observed (0.3% versus 0.1%, P = 0.34). TOSCA is the first trial comparing 3 versus 6 months of adjuvant chemotherapy completing accrual within the international initiative of treatment duration evaluation (International Duration Evaluation of Adjuvant, IDEA). High compliance to treatment in control arm will allow a correct assessment of potential differences between the two treatment durations. NCT00646607. © The Author 2016. Published by Oxford University Press on behalf of the European Society for Medical Oncology. All rights reserved. For permissions, please email: journals.permissions@oup.com.
ERIC Educational Resources Information Center
Crelinsten, Michael, Ed.
Part of the documentation for Katimavik, a nine-month volunteer community service and learning program for 17 to 21-year-old Canadians, the bilingual student manual focuses on the work skills portion of the learning program. The manual includes learning program objectives, trimester guidelines and a checklist for activity participation, optional…
78 FR 54200 - Virginia: Final Authorization of State Hazardous Waste Management Program Revisions
Federal Register 2010, 2011, 2012, 2013, 2014
2013-09-03
... take effect. We will then respond to public comments in a later final rule based on this proposal. You... Programs, U.S. EPA Region III, 1650 Arch Street, Philadelphia, PA 19103-2029. 4. Hand Delivery: At the... 3LC50, Office of State Programs, U.S. EPA Region III, 1650 Arch Street, Philadelphia, PA 19103-2029...
ERIC Educational Resources Information Center
Office of English Language Acquisition, US Department of Education, 2013
2013-01-01
This is the fourth biennial report to Congress on the implementation of the "Elementary and Secondary Education Act's" Title III State Formula Grant Program (also known as the English Language Acquisition State Grants Program). This report provides information reported by states to the U.S. Department of Education regarding services…
ERIC Educational Resources Information Center
Office of English Language Acquisition, US Department of Education, 2012
2012-01-01
This is the third biennial report to Congress on the implementation of the "Elementary and Secondary Education Act's" Title III State Formula Grant Program (also known as the English Language Acquisition State Grants Program). This report provides information regarding the U.S. Department of Education's efforts to hold states accountable…
42 CFR 408.65 - Payment options.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 42 Public Health 2 2010-10-01 2010-10-01 false Payment options. 408.65 Section 408.65 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES MEDICARE PROGRAM PREMIUMS FOR SUPPLEMENTARY MEDICAL INSURANCE Direct Remittance: Individual Payment § 408.65 Payment options...
Efficient Trajectory Options Allocation for the Collaborative Trajectory Options Program
NASA Technical Reports Server (NTRS)
Rodionova, Olga; Arneson, Heather; Sridhar, Banavar; Evans, Antony
2017-01-01
The Collaborative Trajectory Options Program (CTOP) is a Traffic Management Initiative (TMI) intended to control the air traffic flow rates at multiple specified Flow Constrained Areas (FCAs), where demand exceeds capacity. CTOP allows flight operators to submit the desired Trajectory Options Set (TOS) for each affected flight with associated Relative Trajectory Cost (RTC) for each option. CTOP then creates a feasible schedule that complies with capacity constraints by assigning affected flights with routes and departure delays in such a way as to minimize the total cost while maintaining equity across flight operators. The current version of CTOP implements a Ration-by-Schedule (RBS) scheme, which assigns the best available options to flights based on a First-Scheduled-First-Served heuristic. In the present study, an alternative flight scheduling approach is developed based on linear optimization. Results suggest that such an approach can significantly reduce flight delays, in the deterministic case, while maintaining equity as defined using a Max-Min fairness scheme.
Code of Federal Regulations, 2011 CFR
2011-01-01
... FEDERAL TRADE COMMISSION THE FAIR CREDIT REPORTING ACT FREE ANNUAL FILE DISCLOSURES § 610.2 Centralized... request methods, at the consumers' option: (i) A single, dedicated Internet website, (ii) A single, dedicated toll-free telephone number; and (iii) Mail directed to a single address; (2) Be designed, funded...
Code of Federal Regulations, 2012 CFR
2012-01-01
... FEDERAL TRADE COMMISSION THE FAIR CREDIT REPORTING ACT FREE ANNUAL FILE DISCLOSURES § 610.2 Centralized... request methods, at the consumers' option: (i) A single, dedicated Internet website, (ii) A single, dedicated toll-free telephone number; and (iii) Mail directed to a single address; (2) Be designed, funded...
Study of Default Options in Advance Directives
2015-06-29
COPD; Severe or Very Severe Airflow Obstruction and/or Receiving or Eligible to Receive Long-term Oxygen Therapy; Idiopathic Pulmonary Fibrosis; Other Interstitial Lung Disease Without Curative Therapy; Congestive Heart Failure; NYHA Class IV or NYHA Class III Plus 1 Hospitalization in the Past Year; Malignancy; Any Stage 3B or 4 Solid Tumor
21 CFR 145.180 - Canned pineapple.
Code of Federal Regulations, 2010 CFR
2010-04-01
... optional ingredients: (i) Natural fruit flavors. (ii) Mint flavor. (iii) Spices, spice oils. (iv) Vinegar... declaration of any spice or seasoning that characterizes the product; for example, “Spice added”, or, in lieu of the word “Spice”, the common name of the spice; or “Seasoned with vinegar” or, in lieu of the word...
5 CFR 870.506 - Optional insurance: Cancelling a waiver.
Code of Federal Regulations, 2010 CFR
2010-01-01
... can increase the number of multiples, upon his/her marriage or divorce, upon a spouse's death, or upon... children, the number of eligible children acquired; and (iii) For divorce or death of a spouse, the total... coverage upon divorce or death of a spouse, if the employee has any eligible children. (ii) An employee...
34 CFR 200.37 - Notice of identification for improvement, corrective action, or restructuring.
Code of Federal Regulations, 2013 CFR
2013-07-01
... of each child enrolled in the school of this identification. (b) The notice referred to in paragraph... explanation of the parents' option to transfer their child to another public school, including the provision... schools to which the child may transfer. (iii) The explanation may include other information on the school...
34 CFR 200.37 - Notice of identification for improvement, corrective action, or restructuring.
Code of Federal Regulations, 2010 CFR
2010-07-01
... of each child enrolled in the school of this identification. (b) The notice referred to in paragraph... explanation of the parents' option to transfer their child to another public school, including the provision... schools to which the child may transfer. (iii) The explanation may include other information on the school...
34 CFR 200.37 - Notice of identification for improvement, corrective action, or restructuring.
Code of Federal Regulations, 2014 CFR
2014-07-01
... of each child enrolled in the school of this identification. (b) The notice referred to in paragraph... explanation of the parents' option to transfer their child to another public school, including the provision... schools to which the child may transfer. (iii) The explanation may include other information on the school...
34 CFR 200.37 - Notice of identification for improvement, corrective action, or restructuring.
Code of Federal Regulations, 2011 CFR
2011-07-01
... of each child enrolled in the school of this identification. (b) The notice referred to in paragraph... explanation of the parents' option to transfer their child to another public school, including the provision... schools to which the child may transfer. (iii) The explanation may include other information on the school...
34 CFR 200.37 - Notice of identification for improvement, corrective action, or restructuring.
Code of Federal Regulations, 2012 CFR
2012-07-01
... of each child enrolled in the school of this identification. (b) The notice referred to in paragraph... explanation of the parents' option to transfer their child to another public school, including the provision... schools to which the child may transfer. (iii) The explanation may include other information on the school...
76 FR 57745 - Agency Information Collection Activities: Submission for OMB Review; Comment Request
Federal Register 2010, 2011, 2012, 2013, 2014
2011-09-16
... Information Collection: Standardized Pharmacy Notice: Your Prescription Cannot be Filled (f/k/a Medicare... eliminate the previously available option of posting the standardized notice at the pharmacy. Revised 423.562(a)(3) and an associated regulatory provision at Sec. 423.128(b)(7)(iii) require the pharmacy to...
Code of Federal Regulations, 2010 CFR
2010-04-01
... a high vacuum in the container. (iii) The color type used only when the product consists of white... manner, before or after being sealed in a container, so as to prevent spoilage. (2) Styles. The optional... liquid in the container, as determined by the method prescribed in paragraph (b)(2)(i) of this section...
42 CFR 447.52 - Minimum and maximum income-related charges.
Code of Federal Regulations, 2013 CFR
2013-10-01
... agency imposes cost sharing under § 447.54, the process by which hospital emergency room services are... option, cost sharing imposed for any service (other than for drugs and non-emergency services furnished... group under § 447.56(a), and (iii) For cost sharing imposed for non-emergency services furnished in an...
40 CFR 80.164 - Certification test fuels.
Code of Federal Regulations, 2014 CFR
2014-07-01
... certification option in § 80.163(a)(1)(iii) are contained in § 80.177. (1) Quantitative specifications for the... compositional data must be collected only from samples of premium gasoline. (ii) The fuel composition survey... and that all survey data must have been collected within three years of the date the certification...
Near-Term Options for Improving Security at Los Angeles International Airport
2004-09-26
the Transportation Security Administration (TSA), the Los Angeles Police Department ( LAPD ), and LAX to make sure the list was reasonable...World Airports; the Transportation Security Agency; the Los Angeles International Airport Police Department ; the Los Angeles Police Department ; the Los ...Airports. iii PREFACE This document assesses near-term security
21 CFR 312.305 - Requirements for all expanded access uses.
Code of Federal Regulations, 2010 CFR
2010-04-01
... options; (iii) The criteria for patient selection or, for an individual patient, a description of the... 21 Food and Drugs 5 2010-04-01 2010-04-01 false Requirements for all expanded access uses. 312.305 Section 312.305 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES...
Successful and stable orthodontic camouflage of a mandibular asymmetry with sliding jigs.
Oliveira, Dauro Douglas; Oliveira, Bruno Franco de; Mordente, Carolina Morsani; Godoy, Gabriela Martins; Soares, Rodrigo Villamarim; Seraidarian, Paulo Isaías
2018-03-12
The purpose of this paper is to present and discuss a simple and low-cost clinical approach to correct an asymmetric skeletal Class III combined to an extensive dental open bite that significantly compromised the occlusal function and smile aesthetics of an adult male patient. The patient did not accept the idealistic surgical-orthodontic treatment option, neither the use of temporary anchorage devices to facilitate the camouflage of the asymmetrical skeletal Class III/open bite. Therefore, a very simple and inexpensive biomechanical approach using sliding jigs in the mandibular arch was implemented as the compensatory treatment of the malocclusion. Although minor enhancements in facial aesthetics were obtained, the occlusal function and dental aesthetics were significantly improved. Furthermore, the patient was very satisfied with his new smile appearance. Some advantages of this treatment option included the small invasiveness and the remarkably low financial costs involved. Moreover, the final results fulfilled all realistic treatment objectives and the patient's expectations. Results remained stable 5 years post-treatment demonstrating that excellent results can be obtained when simple and low cost, but well-controlled mechanics are conducted.
Emerging pharmacological therapies in schizophrenia: what's new, what's different, what's next?
Citrome, Leslie
2016-12-01
There are several new and emerging medication interventions for both the acute and maintenance treatment phases of schizophrenia. Recently approved are 2 new dopamine receptor partial agonists, brexpiprazole and cariprazine, as well as 2 new long-acting injectable antipsychotic formulations, aripiprazole lauroxil and 3-month paliperidone palmitate. Although differences in efficacy compared to other available choices are not expected, the new oral options offer different tolerability profiles that may be attractive for individual patients who have had difficulties with older medications. The new long-acting injectable options provide additional flexibility in terms of increasing the time interval between injections. In Phase III of clinical development is a novel antipsychotic, lumateperone (ITI-007), that appears to have little in the way of significant adverse effects. Deutetrabenazine and valbenazine are agents in Phase III for the treatment of tardive dyskinesia, a condition that can be found among persons receiving chronic antipsychotic therapy. On the horizon are additional injectable formulations of familiar antipsychotics, aripiprazole and risperidone, that may be more convenient than what is presently available.
Federal Register 2010, 2011, 2012, 2013, 2014
2012-10-24
... Organizations; C2 Options Exchange, Incorporated; Order Approving a Proposed Rule Change To Adopt a Designated... thereunder,\\2\\ a proposed rule change to adopt a Designated Primary Market-Maker (``DPM'') program. The... the Notice, C2 has proposed to adopt a DPM program. The associated proposed rules are based on the...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-04-07
... clearing organizations. In the internal cross-margining program, there is no need for two separate accounts... Organizations; The Options Clearing Corporation; Notice of Filing of Proposed Rule Change to Allow for an Expansion of OCC's Internal Cross-Margining Program to Include the Ability of a Pair of Affiliated Clearing...
Federal Register 2010, 2011, 2012, 2013, 2014
2012-05-25
... program related to an incentive plan for certain Foreign Currency (``FX'') options traded on the Exchange... Rule Change to Terminate a Pilot Program Related to an Incentive Plan for Certain Foreign Currency Options Traded on the Exchange and To Make a Technical Change to the Schedule of Fees May 21, 2012...
Federal Register 2010, 2011, 2012, 2013, 2014
2012-07-06
... Rule Change To Extend the Penny Pilot Program June 28, 2012. Pursuant to Section 19(b)(1) \\1\\ of the... December 31, 2012, the Penny Pilot Program (``Penny Pilot'') in options classes in certain issues (``Pilot... applicable to BATS Options' participation in the Penny Pilot, were approved on January 26, 2010. See...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-06-24
... Change To Extend the Penny Pilot Program June 18, 2013. Pursuant to Section 19(b)(1) of the Securities... December 31, 2013, the Penny Pilot Program (``Penny Pilot'') in options classes in certain issues (``Pilot... applicable to BATS Options' participation in the Penny Pilot, were approved on January 26, 2010. See...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-06-24
... Proposed Rule Change Relating to Extension of the Exchange's Penny Pilot Program and Replacement of Penny... NASDAQ Options Market (``NOM'') to extend through December 31, 2013, the Penny Pilot Program in options classes in certain issues (``Penny Pilot'' or ``Pilot''), and to change the date when delisted classes may...
Federal Register 2010, 2011, 2012, 2013, 2014
2012-12-19
... Proposed Rule Change To Extend the Penny Pilot Program December 13, 2012. Pursuant to Section 19(b)(1) of... Proposed Rule Change BOX Options Exchange LLC (the ``Exchange'') proposes to amend Rule 7260 (Penny Pilot... penny increments (``Penny Pilot Program''). The text of the proposed rule change is available from the...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-01-07
... Effectiveness of a Proposed Rule Change Relating to the Exchange Penny Pilot Program December 31, 2012. Pursuant... its rules relating to the Penny Pilot Program. The text of the proposed rule change is provided below... decimal increments for bids and offers for all series of the option classes participating in the Penny...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-12-23
... Proposed Rule Change Relating to Extension of the Exchange's Penny Pilot Program and Replacement of Penny... the rules of the NASDAQ Options Market (``NOM'') to extend through June 30, 2014, the Penny Pilot Program in options classes in certain issues (``Penny Pilot'' or ``Pilot''), and to change the date when...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-12-20
... Change To Extend the Penny Pilot Program December 16, 2013. Pursuant to Section 19(b)(1) of the... through June 30, 2014, the Penny Pilot Program (``Penny Pilot'') in options classes in certain issues... rules applicable to BATS Options' participation in the Penny Pilot, were approved on January 26, 2010...
5 CFR 870.603 - Conversion of Basic and Optional insurance.
Code of Federal Regulations, 2011 CFR
2011-01-01
... 5 Administrative Personnel 2 2011-01-01 2011-01-01 false Conversion of Basic and Optional... SERVICE REGULATIONS (CONTINUED) FEDERAL EMPLOYEES' GROUP LIFE INSURANCE PROGRAM Termination and Conversion § 870.603 Conversion of Basic and Optional insurance. (a)(1) When group coverage terminates for any...
40 CFR 158.510 - Tiered testing options for nonfood pesticides.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 40 Protection of Environment 25 2013-07-01 2013-07-01 false Tiered testing options for nonfood pesticides. 158.510 Section 158.510 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS DATA REQUIREMENTS FOR PESTICIDES Toxicology § 158.510 Tiered testing options for nonfood...
42 CFR 438.356 - State contract options.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 42 Public Health 4 2010-10-01 2010-10-01 false State contract options. 438.356 Section 438.356 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS MANAGED CARE External Quality Review § 438.356 State contract options...
Olchanski, Natalia; Mathews, Charles; Fusfeld, Lauren; Jarvis, William
2011-03-01
To compare the impacts of different methicillin-resistant Staphylococcus aureus (MRSA) screening test options (eg, polymerase chain reaction [PCR], rapid culture) and program characteristics on the clinical outcomes and budget of a typical US hospital. We developed an Excel-based decision-analytic model, using published literature to calculate and compare hospital costs and MRSA infection rates for PCR- or culture-based MRSA screening and then used multivariate sensitivity analysis to evaluate key variables. Same-day PCR testing for a representative 370-bed teaching hospital in the United States was assessed in different populations (high-risk patients, intensive care unit [ICU] patients, or all patients) and compared with other test options. Different screening program populations (all patients, high-risk patients, ICU patients, or patients with previous MRSA colonization or infection only) represented a potential savings of $12,158-$76,624 per month over no program ($188,618). Analysis of multiple test options in high-risk population screening indicated that same-day PCR testing of high-risk patients resulted in fewer infections over 1,720 patient-days (2.9, compared with 3.5 for culture on selective media and 3.8 for culture on nonselective media) and the lowest total cost ($112,012). The costs of other testing approaches ranged from $113,742 to $123,065. Sensitivity analysis revealed that variations in transmission rate, conversion to infection, prevalence increases, and hospital size are important to determine program impact. Among test characteristics, turnaround time is highly influential. All screening options showed reductions in infection rates and cost impact improvement over no screening program. Among the options, same-day PCR testing for high-risk patients slightly edges out the others in terms of fewest infections and greatest potential cost savings.
Palliative Care Options for a Young Adult Patient with a Diffuse Intrinsic Pontine Glioma.
Sison, Julian; Tran, Hung; Margol, Ashley; Tiwari, Nishant; Garcia, Karla M; Cotter, Jennifer; Kiehna, Erin; Olch, Arthur J; Wong, Kenneth
2017-08-18
Diffuse intrinsic pontine gliomas (DIPGs) are rare but devastating brain tumors that occur primarily in children. These gliomas have poor prognoses and present options focus on palliation of symptoms and prolongation of life. Here, we present a case of a 16-year-old female diagnosed with a DIPG whose age group has been mostly left out of discussions regarding psychosocial support options. This report is meant to start a conversation about the different support options available at our institution that have shown promising results in the literature for palliative care applications. These options can include camps for patients with brain tumors, psychological counseling, the Ronald McDonald House, and other psychosocial programs. Many of these programs can be tailored to meet the specific needs of adolescent and young adult (AYA) patients and will hopefully be integrated into a comprehensive palliative care regimen in future studies.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
1977-11-01
Ford, Bacon and Davis Utah Inc. has performed an engineering assessment of the problems resulting from the existence of radioactive uranium mill tailings at Durango, Colorado. The Phase II, Title I services include the preparation of topographic maps, the performance of core drillings and radiometric measurements sufficient to determine areas and volumes of tailings and other radium-contaminated materials, the evaluation of resulting radiation exposures of individuals and nearby populations, the investigation of site hydrology and meteorology and the evaluation and costing of alternative corrective actions. Radon gas release from the 1.555 million tons of tailings at the Durango site constitutesmore » the most significant environmental impact, although windblown tailings and external gamma radiation are also factors. The eight alternative actions presented range from vegetative stabilization (Option I), to contouring and stabilizing in-place with varying depths of cover material (Options II and III), to removal to an isolated long-term disposal site (Options V to VIII). All options include remedial action costs for offsite locations where tailings have been placed. Costs estimated for the eight options range from $4,340,000 to $13,590,000. Reprocessing the tailings for uranium is sufficiently economically attractive to justify reprocessing in conjunction with each of the options.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
1977-11-01
Ford, Bacon and Davis Utah Inc. has performed an engineering assessment of the problems resulting from the existence of radioactive uranium mill tailings at Durango, Colorado. The Phase II, Title I services include the preparation of topographic maps, the performance of core drillings and radiometric measurements sufficient to determine areas and volumes of tailings and other radium-contaminated materials, the evaluation of resulting radiation exposures of individuals and nearby populations, the investigation of site hydrology and meteorology and the evaluation and costing of alternative corrective actions. Radon gas release from the 1.555 million tons of tailings at the Durango site constitutesmore » the most significant environmental impact, although windblown tailings and external gamma radiation are also factors. The eight alternative actions presented range from vegetative stabilization (Option I), to contouring and stabilizing in-place with varying depths of cover material (Options II and III), to removal to an isolated long-term disposal site (Options V to VIII). All options include remedial action costs for offsite locations where tailings have been placed. Costs estimated for the eight options range from $4,340,000 to $13,590,000. Reprocessing the tailings for uranium is sufficiently economically attractive to justify reprocessing in conjunction with each of the options.« less
Goodman, Karyn A; Patton, Caroline E; Fisher, George A; Hoffe, Sarah E; Haddock, Michael G; Parikh, Parag J; Kim, John; Baxter, Nancy N; Czito, Brian G; Hong, Theodore S; Herman, Joseph M; Crane, Christopher H; Hoffman, Karen E
2016-01-01
To summarize results of a Clinical Practice Statement on radiation therapy for stage II-III rectal cancer, which addressed appropriate customization of (neo)adjuvant radiation therapy and use of non-surgical therapy for patients who are inoperable or refuse abdominoperineal resection. The RAND/University of California, Los Angeles, Appropriateness Method was applied to combine current evidence with multidisciplinary expert opinion. A systematic literature review was conducted and used by the expert panel to rate appropriateness of radiation therapy options for different clinical scenarios. Treatments were categorized by median rating as Appropriate, May Be Appropriate, or Rarely Appropriate. In the neoadjuvant setting, chemoradiation was rated Appropriate and the ratings indicated short-course radiation therapy, chemotherapy alone, and no neoadjuvant therapy are potential options in selected patients. However, neoadjuvant endorectal brachytherapy was rated Rarely Appropriate. For adjuvant therapy, chemoradiation (plus ≥4 months of chemotherapy) was rated Appropriate and chemotherapy alone May Be Appropriate for most scenarios. For medically inoperable patients, definitive external beam radiation therapy and chemotherapy alone were rated May Be Appropriate, whereas endorectal brachytherapy and chemoradiation plus endorectal brachytherapy were possible approaches for some scenarios. The last option, definitive chemoradiation, was rated Appropriate to May Be Appropriate based on performance status. Finally, for patients with low-lying tumors refusing abdominoperineal resection, definitive chemoradiation alone, chemoradiation plus endorectal brachytherapy, and chemoradiation plus external beam radiation therapy were all rated Appropriate. This Clinical Practice Statement demonstrated the central role of radiation therapy in stage II-III rectal cancer management and evaluated ways to better individualize its use in the neoadjuvant, adjuvant, and definitive settings. Ongoing trials may clarify areas of continuing uncertainty and allow further customization. Copyright © 2015 American Society for Radiation Oncology. Published by Elsevier Inc. All rights reserved.
Evolution of Class III treatment in orthodontics.
Ngan, Peter; Moon, Won
2015-07-01
Angle, Tweed, and Moyers classified Class III malocclusions into 3 types: pseudo, dentoalveolar, and skeletal. Clinicians have been trying to identify the best timing to intercept a Class III malocclusion that develops as early as the deciduous dentition. With microimplants as skeletal anchorage, orthopedic growth modification became more effective, and it also increased the scope of camouflage orthodontic treatment for patients who were not eligible for orthognathic surgery. However, orthodontic treatment combined with orthognathic surgery remains the only option for patients with a severe skeletal Class III malocclusion or a craniofacial anomaly. Distraction osteogenesis can now be performed intraorally at an earlier age. The surgery-first approach can minimize the length of time that the malocclusion needs to worsen before orthognathic surgery. Finally, the use of computed tomography scans for 3-dimensional diagnosis and treatment planning together with advances in imaging technology can improve the accuracy of surgical movements and the esthetic outcomes for these patients. Copyright © 2015 American Association of Orthodontists. Published by Elsevier Inc. All rights reserved.
Benyahia, Hicham; Azaroual, Mohamed Faouzi; Garcia, Claude; Hamou, Edith; Abouqal, Redouane; Zaoui, Fatima
2011-06-01
The choice of treatment in adult skeletal Class III occlusions often poses a particularly tricky problem for the orthodontist. Faced with the option of either orthodontic camouflage or orthognathic surgery, the clinician's clinical experience is of paramount importance, especially in borderline cases. The aim of our study was to uncover a guide model enabling the practitioner to distinguish between skeletal Class III cases which can be suitably treated with orthodontics and those requiring orthognathic surgery. The lateral headfilms of 47 adult patients exhibiting skeletal Class III occlusions were analyzed. The orthodontic group comprised 22 patients and the surgical group 25. Twenty-seven linear, proportional and angular measurements were scrutinized. Stepwise discriminant analysis was used to identify the dentoskeletal and esthetic variables which most distinguished the two groups. The Holdaway angle was chosen to differentiate between patients prior to treatment. This model enables us to classify 87.2% of patients correctly. Copyright © 2011 CEO. Published by Elsevier Masson SAS. All rights reserved.
NASA Astrophysics Data System (ADS)
Baaquie, Belal E.
2007-09-01
Foreword; Preface; Acknowledgements; 1. Synopsis; Part I. Fundamental Concepts of Finance: 2. Introduction to finance; 3. Derivative securities; Part II. Systems with Finite Number of Degrees of Freedom: 4. Hamiltonians and stock options; 5. Path integrals and stock options; 6. Stochastic interest rates' Hamiltonians and path integrals; Part III. Quantum Field Theory of Interest Rates Models: 7. Quantum field theory of forward interest rates; 8. Empirical forward interest rates and field theory models; 9. Field theory of Treasury Bonds' derivatives and hedging; 10. Field theory Hamiltonian of forward interest rates; 11. Conclusions; Appendix A: mathematical background; Brief glossary of financial terms; Brief glossary of physics terms; List of main symbols; References; Index.
Federal Register 2010, 2011, 2012, 2013, 2014
2011-08-23
... (ADEC) in four phases. Phases I-III have been transferred from the EPA to ADEC. In March 2011, ADEC made a submission for approval for a one year extension of the transfer of Phase IV of the APDES program... facilities not previously transferred in Phases I-III. The EPA approved the one year extension for Phase IV...
Nuclear Engine System Simulation (NESS). Version 2.0: Program user's guide
NASA Technical Reports Server (NTRS)
Pelaccio, Dennis G.; Scheil, Christine M.; Petrosky, Lyman
1993-01-01
This Program User's Guide discusses the Nuclear Thermal Propulsion (NTP) engine system design features and capabilities modeled in the Nuclear Engine System Simulation (NESS): Version 2.0 program (referred to as NESS throughout the remainder of this document), as well as its operation. NESS was upgraded to include many new modeling capabilities not available in the original version delivered to NASA LeRC in Dec. 1991, NESS's new features include the following: (1) an improved input format; (2) an advanced solid-core NERVA-type reactor system model (ENABLER 2); (3) a bleed-cycle engine system option; (4) an axial-turbopump design option; (5) an automated pump-out turbopump assembly sizing option; (6) an off-design gas generator engine cycle design option; (7) updated hydrogen properties; (8) an improved output format; and (9) personal computer operation capability. Sample design cases are presented in the user's guide that demonstrate many of the new features associated with this upgraded version of NESS, as well as design modeling features associated with the original version of NESS.
Final Report: Pilot Region-Based Optimization Program for Fund-Lead Sites, EPA Region III
This report describes a pilot study for a Region-based optimization program, implemented by a Regional Optimization Evaluation Team (ROET) that was conducted in U.S. EPA Region III at Fund-lead sites with pump-and-treat (P&T) systems.
NASA Technical Reports Server (NTRS)
Allan, R. D.
1978-01-01
The Definition Study of a Variable Cycle Experimental Engine (VCEE) and Associated Test Program and Test Plan, was initiated to identify the most cost effective program for a follow-on to the AST Test Bed Program. The VCEE Study defined various subscale VCE's based on different available core engine components, and a full scale VCEE utilizing current technology. The cycles were selected, preliminary design accomplished and program plans and engineering costs developed for several program options. In addition to the VCEE program plans and options, a limited effort was applied to identifying programs that could logically be accomplished on the AST Test Bed Program VCE to extend the usefulness of this test hardware. Component programs were provided that could be accomplished prior to the start of a VCEE program.
24 CFR 206.107 - Mortgagee election of assignment or shared premium option.
Code of Federal Regulations, 2010 CFR
2010-04-01
... Obligations Mortgage Insurance Premiums § 206.107 Mortgagee election of assignment or shared premium option... shared premium option. 206.107 Section 206.107 Housing and Urban Development Regulations Relating to... COMMISSIONER, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT MORTGAGE AND LOAN INSURANCE PROGRAMS UNDER NATIONAL...
24 CFR 206.107 - Mortgagee election of assignment or shared premium option.
Code of Federal Regulations, 2011 CFR
2011-04-01
... Obligations Mortgage Insurance Premiums § 206.107 Mortgagee election of assignment or shared premium option... shared premium option. 206.107 Section 206.107 Housing and Urban Development Regulations Relating to... COMMISSIONER, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT MORTGAGE AND LOAN INSURANCE PROGRAMS UNDER NATIONAL...
Development and 10-year history of a biosimilar: the example of Binocrit®
Aapro, Matti; Krendyukov, Andriy; Höbel, Nadja; Seidl, Andreas; Gascón, Pere
2018-01-01
Patent expirations for several biological products have prompted the development of alternative versions, termed ‘biosimilars’, which have comparable quality, safety and efficacy to a licensed biological medicine (also referred to as the ‘reference’ medicine). The first biosimilars developed in oncology were the supportive-care agents filgrastim and epoetin. Binocrit® (HX575) is a biosimilar version of epoetin alfa, indicated in the oncology setting for the treatment of chemotherapy-induced anemia (CIA). The process for development and approval of Binocrit® as a biosimilar included extensive analytical characterization and comparison with the reference epoetin alfa. This was followed by a clinical development program comprising phase I pharmacokinetic/pharmacodynamic studies to show bioequivalence to the reference medicine and a confirmatory phase III study to confirm therapeutic effectiveness in CIA. Since its approval, Binocrit® has been extensively used and studied in real-world clinical practice. The accumulated data confirm that Binocrit® is an effective and well-tolerated option for the treatment of CIA in patients with cancer.
The role of the sickness funds in the Belgian health care market.
Nonneman, W; van Doorslaer, E
1994-11-01
This article reviews some of the salient features of the Belgian health care finance and delivery system. Special attention is paid to the role played by the third-party payers, i.e. the Health Insurance Associations (HIAs) in administering the compulsory national health insurance program. It is shown how, despite extensive government regulation, the markets for GP, specialist and hospital services exhibit fierce competition of the non-price variety. Next, the paper considers the three problems perceived to be the most pressing ones at present: (i) the problem of raising sufficient revenues to cover the public share of health expenditures; (ii) the (related) cost containment problem; and (iii) the problem of ensuring efficiency through appropriate incentive mechanisms. Finally, two recently proposed options for reform are discussed and complemented with a third proposal based on the ideas of regulated competition. It is concluded that strengthening the role of the third-party payers remains crucial in any attempt to reshape the system to make it efficient and affordable while keeping it equitable.
Navy CG(X) Cruiser Program: Background, Oversight Issues, and Options for Congress
2009-06-04
Options for Congress 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e . TASK NUMBER 5f. WORK UNIT...Inside the Navy, October 27, 2008. Another press report (Katherine McIntire Peters, “Navy’s Top Officer Sees Lessons in Shipbuilding Program...X)s could change.38 A related question is whether the schedule for procuring CG(X)s is properly aligned with foreign-country ballistic missile
Navy CG(X) Cruiser Program: Background, Oversight Issues, and Options for Congress
2009-12-22
and Options for Congress 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e . TASK NUMBER 5f. WORK...press report (Katherine McIntire Peters, “Navy’s Top Officer Sees Lessons in Shipbuilding Program Failures,” GovernmentExecutive.com, September 24, 2008...changes would have led to a bigger problem—a future surface combatant force that was both unaffordable and poorly aligned with projected mission needs
Navy LPD-17 Amphibious Ship Procurement: Background, Issues, and Options for Congress
2011-04-20
and Options for Congress 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e . TASK NUMBER 5f...construction sequence and application of lessons learned for follow-on vessels in these programs. In the LPD 17 program, the Navy’s reliance on an immature...deeply concerned about Northrop Grumman Ship Systems’ ( NGSS ) ability to recover in the aftermath of Hurricane Katrina, particularly in regard to
Navy CG(X) Cruiser Program: Background, Oversight Issues, and Options for Congress
2009-07-17
Options for Congress 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e . TASK NUMBER 5f. WORK...McIntire Peters, “Navy’s Top Officer Sees Lessons in Shipbuilding Program Failures,” GovernmentExecutive.com, September 24, 2008) quoted Admiral Gary...defined, the total required number of CG(X)s could change.38 A related question is whether the schedule for procuring CG(X)s is properly aligned
The $2000 Electric Powertrain Option-1 Program. Final technical report
DOE Office of Scientific and Technical Information (OSTI.GOV)
NONE
1999-06-01
This report describes the tasks accomplished as part of Northrop Grumman's TRP $2000 Electric Powertrain Option-1 program. Northrop Grumman has strived to achieve technology advances and development considered as high priority to the success of future electric vehicles. Northrop Grumman has achieved the intent of the program by taking several steps toward reducing the cost of the electric vehicle powertrain, demonstrating technologies in the form of hardware and introducing enhancements into production that are consistent with the needs of the market.
Garvelink, Mirjam Marjolein; Jones, C Allyson; Archambault, Patrick M; Roy, Noémie; Blair, Louisa; Légaré, France
2017-12-14
Seniors with loss of autonomy may face decisions about whether they should stay at home or move elsewhere. Most seniors would prefer to stay home and be independent for as long as possible, but most are unaware of options that would make this possible. The study aimed to develop and test the acceptability of an interactive website for seniors, their caregivers, and health professionals with short interlinked videos presenting information about options for staying independent at home. The approach for design and data collection varied, involving a multipronged, user-centered design of the development process, qualitative interviews, and end-user feedback to determine content (ie, needs assessment) in phase I; module development (in English and French) in phase II; and survey to test usability and acceptability with end users in phase III. Phase I participants were a convenience sample of end users, that is, seniors, caregivers, and professionals with expertise in modifiable factors (eg, day centers, home redesign, equipment, community activities, and finances), enabling seniors to stay independent at home for longer in Quebec and Alberta, Canada. Phase II participants were bilingual actors; phase III participants included phase I participants and new participants recruited through snowballing. Qualitative interviews were thematically analyzed in phase II to determine relevant topics for the video-scripts, which were user-checked by interview participants. In phase III, the results of a usability questionnaire were analyzed using descriptive statistics. In phase I, interviews with 29 stakeholders, including 4 seniors, 3 caregivers, and 22 professionals, showed a need for a one-stop information resource about options for staying independent at home. They raised issues relating to 6 categories: cognitive autonomy, psychological or mental well-being, functional autonomy, social autonomy, financial autonomy, and people involved. A script was developed and evaluated by participants. In phase II, after 4 days in a studio with 15 bilingual actors, 30 videos were made of various experts (eg, family doctor, home care nurse, and social worker) presenting options and guidance for the decision-making process. These were integrated into an interactive website, which included a comments tool for visitors to add information. In phase III (n=21), 8 seniors (7 women, mean age 75 years), 7 caregivers, and 6 professionals evaluated the acceptability of the module and suggested improvements. Clarity of the videos scored 3.6 out of 4, length was considered right by 17 (separate videos) and 13 participants (all videos together), and 18 participants considered the module acceptable. They suggested that information should be tailored more, and that seniors may need someone to help navigate it. Our interactive website with interlinked videos presenting information about options for staying independent at home was deemed acceptable and potentially helpful by a diverse group of stakeholders. ©Mirjam Marjolein Garvelink, C Allyson Jones, Patrick M Archambault, Noémie Roy, Louisa Blair, France Légaré. Originally published in JMIR Human Factors (http://humanfactors.jmir.org), 14.12.2017.
Space Civil Engineering option - A progress report
NASA Technical Reports Server (NTRS)
Criswell, Marvin E.; Sadeh, Willy Z.
1992-01-01
Space Civil Engineering is an emerging engineering discipline that focuses on extending and expanding Civil Engineering to the development, operation, and maintenance of infrastructures on celestial bodies. Space Civil Engineering is presently being developed as a new discipline within the Department of Civil Engineering at Colorado State University and with support of the NASA Space Grant College Program. Academic programs geared toward creating Space Civil Engineering Options at both undergraduate and graduate levels are being formulated. Basic ideas and concepts and the current status of the curriculum in the Space Civil Engineering Option primarily at the undergraduate level are presented.
ERIC Educational Resources Information Center
George Washington Univ., Washington, DC. Inst. for Educational Leadership.
"Options in Education" is a weekly radio magazine covering news, features, policy, and people in the field of education produced by National Public Radio and the Institute for Educational Leadership. This broadcast presents Geoffrey Blodgett discussing students' heroes, villains, and ideals; Rose Tobin on student mood at Berkeley; and…
ERIC Educational Resources Information Center
Martínez, Yolanda García; Velázquez, Claudia Alvarado; Castillo, Rolando Delgado
2016-01-01
This paper pursues to define the pillars for designing the specific (SC) and optional curricula (OC) of Unit Operations and Processes (UOP) Discipline in the Chemical Engineering Program. To achieve this objective a methodology was developed, which was characterized by the participation of every member in the educational process: professors,…
Nondegree Options for Expanding a Leadership Portfolio.
Bleich, Michael R; Jones-Schenk, Jan
2016-07-01
Organizational leaders are time-challenged to stay attuned with dynamic health care and business environments, leaving time for professional development at a premium. Beyond interorganizational leadership programs, learning options for nondegree-enhanced education are provided, referencing some of the high-quality, high-volume programs available at no or low cost. J Contin Educ Nurs. 2016;47(7):299-301. Copyright 2016, SLACK Incorporated.
2013-12-01
Programming code in the Python language used in AIS data preprocessing is contained in Appendix A. The MATLAB programming code used to apply the Hough...described in Chapter III is applied to archived AIS data in this chapter. The implementation of the method, including programming techniques used, is...is contained in the second. To provide a proof of concept for the algorithm described in Chapter III, the PYTHON programming language was used for
78 FR 18325 - Defense Transportation Regulation, Part IV
Federal Register 2010, 2011, 2012, 2013, 2014
2013-03-26
... received in connection with the Defense Personal Property Program (DP3) Phase III Direct Procurement Method... at http://www.transcom.mil/dtr/part-iv/phaseiii.cfm (DPM SECTION). All identified changes will be... Defense Personal Property System (DPS) Phase III programming projected for FY17. FOR FURTHER INFORMATION...
76 FR 36095 - Defense Transportation Regulation, Part IV
Federal Register 2010, 2011, 2012, 2013, 2014
2011-06-21
... with the Defense Personal Property Program (DP3) Phase III Domestic Small Shipments (dS2) and... Regulation, Part IV Web site at http://www.transcom.mil/dtr/part-iv/phaseiii.cfm . All identified changes... based on completion of Defense Personal Property System (DPS) Phase III programming projected for FY15...
Software Reviews: Programs Worth a Second Look.
ERIC Educational Resources Information Center
Classroom Computer Learning, 1989
1989-01-01
Reviewed are three computer software programs: (1) "World GeoGraph"--geography, discovery tool, grades 6-12, Apple IIGS; (2) "Grammatik III"--language arts, grade 7-adult, IBM, PS/2, Tandy 1000; (3) "Words & Concepts I, II, III"--language and concept training for special education, age 3-9, Apple II with speech…
75 FR 27538 - Submission for OMB Review; Comment Request
Federal Register 2010, 2011, 2012, 2013, 2014
2010-05-17
... Paperwork Reduction Act (44 U.S.C. Chapter 35). Agency: Green Technology Pilot Program. Form Number(s): PTO... Examination Pilot Program for Green Technologies, (ii) the public may protest a pending application, and (iii...'s Obligation: Required to obtain or retain benefits. OMB Desk Officer: Nicholas A. Fraser, e-mail...
76 FR 67764 - Finance, Budget & Program Committee Board of Directors Meeting; Sunshine Act
Federal Register 2010, 2011, 2012, 2013, 2014
2011-11-02
... NEIGHBORHOOD REINVESTMENT CORPORATION Finance, Budget & Program Committee Board of Directors..., Assistant Corporate Secretary (202) 220-2376; [email protected] . Agenda: I. Call To Order II. Executive Session III. Financial Report III. Budget Report IV. Lease Update V. Corporate Scorecard VI. NFMC & EHLP VII...
Quantitative option analysis for implementation and management of landfills.
Kerestecioğlu, Merih
2016-09-01
The selection of the most feasible strategy for implementation of landfills is a challenging step. Potential implementation options of landfills cover a wide range, from conventional construction contracts to the concessions. Montenegro, seeking to improve the efficiency of the public services while maintaining affordability, was considering privatisation as a way to reduce public spending on service provision. In this study, to determine the most feasible model for construction and operation of a regional landfill, a quantitative risk analysis was implemented with four steps: (i) development of a global risk matrix; (ii) assignment of qualitative probabilities of occurrences and magnitude of impacts; (iii) determination of the risks to be mitigated, monitored, controlled or ignored; (iv) reduction of the main risk elements; and (v) incorporation of quantitative estimates of probability of occurrence and expected impact for each risk element in the reduced risk matrix. The evaluated scenarios were: (i) construction and operation of the regional landfill by the public sector; (ii) construction and operation of the landfill by private sector and transfer of the ownership to the public sector after a pre-defined period; and (iii) operation of the landfill by the private sector, without ownership. The quantitative risk assessment concluded that introduction of a public private partnership is not the most feasible option, unlike the common belief in several public institutions in developing countries. A management contract for the first years of operation was advised to be implemented, after which, a long term operating contract may follow. © The Author(s) 2016.
Quick-start guide for version 3.0 of EMINERS - Economic Mineral Resource Simulator
Bawiec, Walter J.; Spanski, Gregory T.
2012-01-01
Quantitative mineral resource assessment, as developed by the U.S. Geological Survey (USGS), consists of three parts: (1) development of grade and tonnage mineral deposit models; (2) delineation of tracts permissive for each deposit type; and (3) probabilistic estimation of the numbers of undiscovered deposits for each deposit type (Singer and Menzie, 2010). The estimate of the number of undiscovered deposits at different levels of probability is the input to the EMINERS (Economic Mineral Resource Simulator) program. EMINERS uses a Monte Carlo statistical process to combine probabilistic estimates of undiscovered mineral deposits with models of mineral deposit grade and tonnage to estimate mineral resources. It is based upon a simulation program developed by Root and others (1992), who discussed many of the methods and algorithms of the program. Various versions of the original program (called "MARK3" and developed by David H. Root, William A. Scott, and Lawrence J. Drew of the USGS) have been published (Root, Scott, and Selner, 1996; Duval, 2000, 2012). The current version (3.0) of the EMINERS program is available as USGS Open-File Report 2004-1344 (Duval, 2012). Changes from version 2.0 include updating 87 grade and tonnage models, designing new templates to produce graphs showing cumulative distribution and summary tables, and disabling economic filters. The economic filters were disabled because embedded data for costs of labor and materials, mining techniques, and beneficiation methods are out of date. However, the cost algorithms used in the disabled economic filters are still in the program and available for reference for mining methods and milling techniques included in Camm (1991). EMINERS is written in C++ and depends upon the Microsoft Visual C++ 6.0 programming environment. The code depends heavily on the use of Microsoft Foundation Classes (MFC) for implementation of the Windows interface. The program works only on Microsoft Windows XP or newer personal computers. It does not work on Macintosh computers. This report demonstrates how to execute EMINERS software using default settings and existing deposit models. Many options are available when setting up the simulation. Information and explanations addressing these optional parameters can be found in the EMINERS Help files. Help files are available during execution of EMINERS by selecting EMINERS Help from the pull-down menu under Help on the EMINERS menu bar. There are four sections in this report. Part I describes the installation, setup, and application of the EMINERS program, and Part II illustrates how to interpret the text file that is produced. Part III describes the creation of tables and graphs by use of the provided Excel templates. Part IV summarizes grade and tonnage models used in version 3.0 of EMINERS.
40 CFR Appendix III to Part 92 - Smoke Standards for Non-Normalized Measurements
Code of Federal Regulations, 2013 CFR
2013-07-01
...) AIR PROGRAMS (CONTINUED) CONTROL OF AIR POLLUTION FROM LOCOMOTIVES AND LOCOMOTIVE ENGINES Pt. 92, App. III Appendix III to Part 92—Smoke Standards for Non-Normalized Measurements Table III-1—Equivalent... 40 Protection of Environment 21 2013-07-01 2013-07-01 false Smoke Standards for Non-Normalized...
40 CFR Appendix III to Part 92 - Smoke Standards for Non-Normalized Measurements
Code of Federal Regulations, 2011 CFR
2011-07-01
...) AIR PROGRAMS (CONTINUED) CONTROL OF AIR POLLUTION FROM LOCOMOTIVES AND LOCOMOTIVE ENGINES Pt. 92, App. III Appendix III to Part 92—Smoke Standards for Non-Normalized Measurements Table III-1—Equivalent... 40 Protection of Environment 20 2011-07-01 2011-07-01 false Smoke Standards for Non-Normalized...
40 CFR Appendix III to Part 92 - Smoke Standards for Non-Normalized Measurements
Code of Federal Regulations, 2012 CFR
2012-07-01
...) AIR PROGRAMS (CONTINUED) CONTROL OF AIR POLLUTION FROM LOCOMOTIVES AND LOCOMOTIVE ENGINES Pt. 92, App. III Appendix III to Part 92—Smoke Standards for Non-Normalized Measurements Table III-1—Equivalent... 40 Protection of Environment 21 2012-07-01 2012-07-01 false Smoke Standards for Non-Normalized...
40 CFR Appendix III to Part 92 - Smoke Standards for Non-Normalized Measurements
Code of Federal Regulations, 2014 CFR
2014-07-01
...) AIR PROGRAMS (CONTINUED) CONTROL OF AIR POLLUTION FROM LOCOMOTIVES AND LOCOMOTIVE ENGINES Pt. 92, App. III Appendix III to Part 92—Smoke Standards for Non-Normalized Measurements Table III-1—Equivalent... 40 Protection of Environment 20 2014-07-01 2013-07-01 true Smoke Standards for Non-Normalized...
40 CFR Appendix III to Part 92 - Smoke Standards for Non-Normalized Measurements
Code of Federal Regulations, 2010 CFR
2010-07-01
...) AIR PROGRAMS (CONTINUED) CONTROL OF AIR POLLUTION FROM LOCOMOTIVES AND LOCOMOTIVE ENGINES Pt. 92, App. III Appendix III to Part 92—Smoke Standards for Non-Normalized Measurements Table III-1—Equivalent... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Smoke Standards for Non-Normalized...
Computer user's manual for a generalized curve fit and plotting program
NASA Technical Reports Server (NTRS)
Schlagheck, R. A.; Beadle, B. D., II; Dolerhie, B. D., Jr.; Owen, J. W.
1973-01-01
A FORTRAN coded program has been developed for generating plotted output graphs on 8-1/2 by 11-inch paper. The program is designed to be used by engineers, scientists, and non-programming personnel on any IBM 1130 system that includes a 1627 plotter. The program has been written to provide a fast and efficient method of displaying plotted data without having to generate any additions. Various output options are available to the program user for displaying data in four different types of formatted plots. These options include discrete linear, continuous, and histogram graphical outputs. The manual contains information about the use and operation of this program. A mathematical description of the least squares goodness of fit test is presented. A program listing is also included.
An implementation of the programming structural synthesis system (PROSSS)
NASA Technical Reports Server (NTRS)
Rogers, J. L., Jr.; Sobieszczanski-Sobieski, J.; Bhat, R. B.
1981-01-01
A particular implementation of the programming structural synthesis system (PROSSS) is described. This software system combines a state of the art optimization program, a production level structural analysis program, and user supplied, problem dependent interface programs. These programs are combined using standard command language features existing in modern computer operating systems. PROSSS is explained in general with respect to this implementation along with the steps for the preparation of the programs and input data. Each component of the system is described in detail with annotated listings for clarification. The components include options, procedures, programs and subroutines, and data files as they pertain to this implementation. An example exercising each option in this implementation to allow the user to anticipate the type of results that might be expected is presented.
77 FR 7640 - Self-Regulatory Organizations; BATS Y-Exchange, Inc.; Notice of Filing and Immediate...
Federal Register 2010, 2011, 2012, 2013, 2014
2012-02-13
... 30 days after the date of the filing, or such shorter time as the Commission may designate, it has...-4(f)(6)(iii) \\8\\ permits the Commission to designate a shorter time if such action is consistent... without further delay. The Exchange notes that the introduction of the additional optional variation of...
Federal Register 2010, 2011, 2012, 2013, 2014
2012-02-13
... 30 days after the date of the filing, or such shorter time as the Commission may designate, it has...-4(f)(6)(iii) \\8\\ permits the Commission to designate a shorter time if such action is consistent... trading costs without further delay. The Exchange notes that the introduction of the additional optional...
38 CFR 36.4253 - Title and lien requirements.
Code of Federal Regulations, 2014 CFR
2014-07-01
..., which right by the terms thereof is exercisable only if: (i) An owner elects to sell, (ii) The option price is not less than the price at which the then owner is willing to sell to another, and (iii... the then owner of the then owner's election to sell, stating the price and the identity of the...
38 CFR 36.4253 - Title and lien requirements.
Code of Federal Regulations, 2012 CFR
2012-07-01
..., which right by the terms thereof is exercisable only if: (i) An owner elects to sell, (ii) The option price is not less than the price at which the then owner is willing to sell to another, and (iii... the then owner of the then owner's election to sell, stating the price and the identity of the...
38 CFR 36.4253 - Title and lien requirements.
Code of Federal Regulations, 2013 CFR
2013-07-01
..., which right by the terms thereof is exercisable only if: (i) An owner elects to sell, (ii) The option price is not less than the price at which the then owner is willing to sell to another, and (iii... the then owner of the then owner's election to sell, stating the price and the identity of the...
38 CFR 36.4253 - Title and lien requirements.
Code of Federal Regulations, 2011 CFR
2011-07-01
..., which right by the terms thereof is exercisable only if: (i) An owner elects to sell, (ii) The option price is not less than the price at which the then owner is willing to sell to another, and (iii... the then owner of the then owner's election to sell, stating the price and the identity of the...
38 CFR 36.4253 - Title and lien requirements.
Code of Federal Regulations, 2010 CFR
2010-07-01
..., which right by the terms thereof is exercisable only if: (i) An owner elects to sell, (ii) The option price is not less than the price at which the then owner is willing to sell to another, and (iii... the then owner of the then owner's election to sell, stating the price and the identity of the...
USDA-ARS?s Scientific Manuscript database
The effects of various production practices on biomass, C, and nutrient content, accumulation, and loss were assessed over 2 years in a mature organic trailing blackberry (Rubus L. subgenus Rubus, Watson) production system. Treatments included two irrigation options (no irrigation after harvest and ...
24 CFR 291.415 - Lease with option to purchase properties for use by the homeless.
Code of Federal Regulations, 2013 CFR
2013-04-01
... child care expenses); (ii) Ten percent of the family's monthly income; or (iii) If the family is.... (d) Damage to leased properties. Any damage to leased property caused by the intentional or negligent... not make the necessary repairs within a reasonable time after the damage occurs, HUD may, at its...
24 CFR 291.415 - Lease with option to purchase properties for use by the homeless.
Code of Federal Regulations, 2012 CFR
2012-04-01
... child care expenses); (ii) Ten percent of the family's monthly income; or (iii) If the family is.... (d) Damage to leased properties. Any damage to leased property caused by the intentional or negligent... not make the necessary repairs within a reasonable time after the damage occurs, HUD may, at its...
24 CFR 291.415 - Lease with option to purchase properties for use by the homeless.
Code of Federal Regulations, 2014 CFR
2014-04-01
... child care expenses); (ii) Ten percent of the family's monthly income; or (iii) If the family is.... (d) Damage to leased properties. Any damage to leased property caused by the intentional or negligent... not make the necessary repairs within a reasonable time after the damage occurs, HUD may, at its...
24 CFR 291.415 - Lease with option to purchase properties for use by the homeless.
Code of Federal Regulations, 2011 CFR
2011-04-01
... child care expenses); (ii) Ten percent of the family's monthly income; or (iii) If the family is.... (d) Damage to leased properties. Any damage to leased property caused by the intentional or negligent... not make the necessary repairs within a reasonable time after the damage occurs, HUD may, at its...
24 CFR 291.415 - Lease with option to purchase properties for use by the homeless.
Code of Federal Regulations, 2010 CFR
2010-04-01
... child care expenses); (ii) Ten percent of the family's monthly income; or (iii) If the family is.... (d) Damage to leased properties. Any damage to leased property caused by the intentional or negligent... not make the necessary repairs within a reasonable time after the damage occurs, HUD may, at its...
34 CFR 200.48 - Funding for choice-related transportation and supplemental educational services.
Code of Federal Regulations, 2012 CFR
2012-07-01
... Agencies Lea and School Improvement § 200.48 Funding for choice-related transportation and supplemental... all requests for supplemental educational services under § 200.45; or (iii) Pay for both paragraph (a... school choice options under § 200.44, in the amounts required under paragraph (a)(2) of this section; and...
34 CFR 200.48 - Funding for choice-related transportation and supplemental educational services.
Code of Federal Regulations, 2014 CFR
2014-07-01
... Agencies Lea and School Improvement § 200.48 Funding for choice-related transportation and supplemental... all requests for supplemental educational services under § 200.45; or (iii) Pay for both paragraph (a... school choice options under § 200.44, in the amounts required under paragraph (a)(2) of this section; and...
Code of Federal Regulations, 2011 CFR
2011-07-01
... the option in paragraph (a)(1)(iii) in § 63.1564 (Ni lb/hr), and you use continuous parameter monitoring systems, you must establish an operating limit for the equilibrium catalyst Ni concentration based on the laboratory analysis of the equilibrium catalyst Ni concentration from the initial performance...
The Effect of an End-of-Clerkship Review Session on NBME Psychiatry Subject Exam Scores
ERIC Educational Resources Information Center
Sidhu, Shawn S.; Chandra, Rohit M.; Wang, Lei; Gollan, Jacqueline K.; Rasminsky, Sonya; Brar, Simerjeet K.; Anzia, Joan M.
2012-01-01
Objective: The NBME Psychiatry Subject Examination (PSE) is used throughout North America to test MS-III end-of-clerkship knowledge; yet, literature on PSE preparatory methods remains sparse. This study assesses the effect of a curriculum intervention on NBME PSE scores. Method: An optional 1.5-hour review session and accompanying…
75 FR 67258 - Position Reports for Physical Commodity Swaps
Federal Register 2010, 2011, 2012, 2013, 2014
2010-11-02
... Cattle. CME Milk Class III. Comex (``CMX'') Copper Grade 1. CMX Gold. CMX Silver. ICE Futures US (``ICUS... Oats. CME Butter. CME Cheese. CME Dry Whey. CME Hardwood Pulp. CME Lean Hogs. CME Non Fat Dry Milk. CME... contract--The ICE WTI Average Price Option is indirectly linked to a 20.2 listed futures contract because...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-01-19
...); (ii) establish a VIX Tier Appointment; (iii) amend the monthly fee for Floor Broker Trading Permits... demutualization, CBOE amended its Fees Schedule to establish Trading Permit, tier appointment and bandwidth packet... permit ($) 1 permit 10 permits 6,000 Tier 1 11 permits 20 permits 4,800 Tier 2 21 or more permits...
40 CFR 53.23 - Test procedures.
Code of Federal Regulations, 2013 CFR
2013-07-01
... up and stabilize. Determine measurement noise at each of two fixed concentrations, first using zero.... Note to § 53.23(b)(2): Use of a chart recorder in addition to the DM is optional. (iii) Measure zero... atmosphere concentration of 80 ±5 percent of the URL instead of zero air, and let S at 80 percent of the URL...
40 CFR 53.23 - Test procedures.
Code of Federal Regulations, 2012 CFR
2012-07-01
... up and stabilize. Determine measurement noise at each of two fixed concentrations, first using zero.... Note to § 53.23(b)(2): Use of a chart recorder in addition to the DM is optional. (iii) Measure zero... atmosphere concentration of 80 ±5 percent of the URL instead of zero air, and let S at 80 percent of the URL...
40 CFR 53.23 - Test procedures.
Code of Federal Regulations, 2014 CFR
2014-07-01
... up and stabilize. Determine measurement noise at each of two fixed concentrations, first using zero.... Note to § 53.23(b)(2): Use of a chart recorder in addition to the DM is optional. (iii) Measure zero... atmosphere concentration of 80 ±5 percent of the URL instead of zero air, and let S at 80 percent of the URL...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-04-17
... System (a) Definition: No change. (b) Types of Complex Orders: No change. (c) Complex Order Book (i)-(iii..., the System will evaluate the COB when a complex order enters the COB, when the Exchange BBO changes... System may generate leg orders for the remaining size of the complex order in accordance with...
26 CFR 1.743-1 - Optional adjustment to basis of partnership property.
Code of Federal Regulations, 2012 CFR
2012-04-01
... acquired partnership interest); and decreased by (iii) The amount of tax gain (including any remedial.... See § 1.460-4(k)(3)(v)(B) for a rule relating to the computation of income or loss that would be... immediately after the hypothetical transaction, decreased by $7,000, the amount of tax gain allocated to T...
26 CFR 1.743-1 - Optional adjustment to basis of partnership property.
Code of Federal Regulations, 2011 CFR
2011-04-01
... acquired partnership interest); and decreased by (iii) The amount of tax gain (including any remedial.... See § 1.460-4(k)(3)(v)(B) for a rule relating to the computation of income or loss that would be... immediately after the hypothetical transaction, decreased by $7,000, the amount of tax gain allocated to T...
26 CFR 1.743-1 - Optional adjustment to basis of partnership property.
Code of Federal Regulations, 2013 CFR
2013-04-01
... acquired partnership interest); and decreased by (iii) The amount of tax gain (including any remedial.... See § 1.460-4(k)(3)(v)(B) for a rule relating to the computation of income or loss that would be... immediately after the hypothetical transaction, decreased by $7,000, the amount of tax gain allocated to T...
26 CFR 1.743-1 - Optional adjustment to basis of partnership property.
Code of Federal Regulations, 2010 CFR
2010-04-01
... acquired partnership interest); and decreased by (iii) The amount of tax gain (including any remedial.... See § 1.460-4(k)(3)(v)(B) for a rule relating to the computation of income or loss that would be... immediately after the hypothetical transaction, decreased by $7,000, the amount of tax gain allocated to T...
26 CFR 1.743-1 - Optional adjustment to basis of partnership property.
Code of Federal Regulations, 2014 CFR
2014-04-01
... acquired partnership interest); and decreased by (iii) The amount of tax gain (including any remedial.... See § 1.460-4(k)(3)(v)(B) for a rule relating to the computation of income or loss that would be... immediately after the hypothetical transaction, decreased by $7,000, the amount of tax gain allocated to T...
1978-08-01
12°±30’ 1180±2° OPTIONAL .0005 IN./IN. BACK TAPER 015 RAD LIPS TO BE WITHIN .002 OF TRUE ANGULAR POSITION NOTES: 1. LAND WIDTH: 28% ± .005... horoscope and dye-penetrant requirements. 79 PHASE 1 PHASE II PHASE III PHASE IV CUTTING DRILLING MACHINING NONDESTRUCTIVE EVALUATION METHOD MATERIAL
50 CFR 680.41 - Transfer of QS, PQS, IFQ and IPQ.
Code of Federal Regulations, 2013 CFR
2013-10-01
...://alaskafisheries.noaa.gov, or by contacting NMFS at: 800-304-4846, Option 2. (c) Eligibility to receive QS, PQS... to any person on request or on the Internet at http://www.fakr.noaa.gov/. (ii) Contents. A complete... permit is issued and the QS holder must re-apply for any subsequent transfers. (iii) NMFS will not...
50 CFR 680.41 - Transfer of QS, PQS, IFQ and IPQ.
Code of Federal Regulations, 2012 CFR
2012-10-01
...://alaskafisheries.noaa.gov, or by contacting NMFS at: 800-304-4846, Option 2. (c) Eligibility to receive QS, PQS... to any person on request or on the Internet at http://www.fakr.noaa.gov/. (ii) Contents. A complete... permit is issued and the QS holder must re-apply for any subsequent transfers. (iii) NMFS will not...