Characterization of 42 Microsatellite Markers from Poison Ivy, Toxicodendron radicans (Anacardiaceae)

PubMed Central

Hsu, Tsai-Wen; Shih, Huei-Chuan; Kuo, Chia-Chi; Chiang, Tzen-Yuh; Chiang, Yu-Chung

2013-01-01

Poison ivy, Toxicodendron radicans, and poison oaks, T. diversilobum and T. pubescens, are perennial woody species of the Anacardiaceae and are poisonous, containing strong allergens named urushiols that cause allergic contact dermatitis. Poison ivy is a species distributed from North America to East Asia, while T. diversilobum and T. pubescens are distributed in western and eastern North America, respectively. Phylogreography and population structure of these species remain unclear. Here, we developed microsatellite markers, via constructing a magnetic enriched microsatellite library, from poison ivy. We designed 51 primer pairs, 42 of which successfully yielded products that were subsequently tested for polymorphism in poison oak, and three subspecies of poison ivy. Among the 42 loci, 38 are polymorphic, while 4 are monomorphic. The number of alleles and the expected heterozygosity ranged from 1 to 12 and from 0.10 to 0.87, respectively, in poison ivy, while varied from 2 to 8 and, from 0.26 to 0.83, respectively in poison oak. Genetic analysis revealed distinct differentiation between poison ivy and poison oak, whereas slight genetic differentiation was detected among three subspecies of poison ivy. These highly polymorphic microsatellite fingerprints enable biologists to explore the population genetics, phylogeography, and speciation in Toxicodendron. PMID:24129176

Poison ivy dermatitis. Nuances in treatment.

PubMed

Williford, P M; Sheretz, E F

1994-02-01

Acute allergic contact dermatitis due to poison ivy or poison oak is a common presenting complaint in the practices of many primary care physicians. While the clinical features are well described, reported treatment regimens vary in both topical and systemic therapies. We review herein the variability of presenting morphologic features of the disease and common treatment regimens, with attention given to complications of therapy. We also comment on the correct botanical designation, incidence, and immune mechanisms of the disease state and review measures to avoid allergic contact dermatitis due to poison ivy and poison oak.

IVI human factors strategy

DOT National Transportation Integrated Search

1999-11-01

This document focuses on human factors research that supports the Intelligent Vehicle Initiative (IVI). The status of the problem areas within categories used often by the human factors community to organize human factors process is discussed. A simi...

Prevention of poison ivy dermatitis with oral homeopathic Rhus toxicodendron.

PubMed

Signore, Robert Joseph

2017-01-15

Acute allergic contact dermatitis to poison ivy is acommon and miserable dermatosis which affectsmillions of Americans each year. Preventativemeasures, such as avoidance, protective clothing,barrier creams, soaps, and solvents often fail despiteour patients' best attempts. Severe allergic reactionsto poison ivy are a significant source of decreasedemployee productivity owing to inability to work anda major health care expenditure. Patients may haveto leave their jobs and discontinue favorite outdoorrecreational activities as a result of severe urushiolsensitivity. Thus, a simple and effective method ofpreventing poison ivy dermatitis would be of greatbenefit to clinical dermatologists and their patients.Complementary and alternative medical practitionerscommonly prescribe homeopathic poison ivyproducts by mouth for the prevention of poisonivy dermatitis. Yet, conventional dermatologists aremostly unaware of this little known clinical pearl. Theauthor discusses two open studies and anecdotalexperience with administration of homeopathicpoison ivy in the prevention of acute allergic contactdermatitis related to poison ivy exposure. Potentialadvantages could include patient acceptability,ease of administration, affordability, and availability.Randomized clinical trials are needed to furtherevaluate the safety and efficacy of this interesting andpromising clinical tip.

Ivy League Trailblazer

ERIC Educational Resources Information Center

Cooper, Kenneth J.

2011-01-01

Ruth Simmons made a big news splash a decade ago when she was named president of Brown University, making her the first Black president of an Ivy League institution. She made another splash three years later by naming a committee to investigate Brown's role in the slave trade and make recommendations on possible reparations. Reflecting on her…

Isolation and chemical analysis of nanoparticles from English ivy (Hedera helix L.)

PubMed Central

Lenaghan, Scott C.; Burris, Jason N.; Chourey, Karuna; Huang, Yujian; Xia, Lijin; Lady, Belinda; Sharma, Ritin; Pan, Chongle; LeJeune, Zorabel; Foister, Shane; Hettich, Robert L.; Stewart, C. Neal; Zhang, Mingjun

2013-01-01

Bio-inspiration for novel adhesive development has drawn increasing interest in recent years with the discovery of the nanoscale morphology of the gecko footpad and mussel adhesive proteins. Similar to these animal systems, it was discovered that English ivy (Hedera helix L.) secretes a high strength adhesive containing uniform nanoparticles. Recent studies have demonstrated that the ivy nanoparticles not only contribute to the high strength of this adhesive, but also have ultraviolet (UV) protective abilities, making them ideal for sunscreen and cosmetic fillers, and may be used as nanocarriers for drug delivery. To make these applications a reality, the chemical nature of the ivy nanoparticles must be elucidated. In the current work, a method was developed to harvest bulk ivy nanoparticles from an adventitious root culture system, and the chemical composition of the nanoparticles was analysed. UV/visible spectroscopy, inductively coupled plasma mass spectrometry, Fourier transform infrared spectroscopy and electrophoresis were used in this study to identify the chemical nature of the ivy nanoparticles. Based on this analysis, we conclude that the ivy nanoparticles are proteinaceous. PMID:23883948

Milia after allergic contact dermatitis from poison ivy: two cases.

PubMed

Berk, David R; Hurt, Mark A; Reese, Lester T; Wagner, Laura; Bayliss, Susan J

2010-01-01

Milia have rarely been reported as a complication of severe allergic contact dermatitis. To our knowledge, milia have not previously been associated with poison ivy dermatitis. We present two cases of milia after allergic contact dermatitis to poison ivy.

Is it, or isn't it? Poison ivy look-a-likes.

PubMed

McGovern, T W; LaWarre, S R; Brunette, C

2000-06-01

Poison ivy causes more allergic contact dermatitis (ACD) than any other cause. Although physicians rightfully focus on the treatment of the dermatitis, prevention will be aided by recognition of the foreboding plant. Likewise, many other plants can masquerade as poison ivy and cause one to needlessly curtail his or her activities because of fear of a bad reaction. The most common poison ivy pretenders in the United States are discussed, and distinguishing plant characteristics are highlighted.

Sequencing and De Novo Assembly of the Toxicodendron radicans (Poison Ivy) Transcriptome

PubMed Central

Kim, Gunjune

2017-01-01

Contact with poison ivy plants is widely dreaded because they produce a natural product called urushiol that is responsible for allergenic contact delayed-dermatitis symptoms lasting for weeks. For this reason, the catchphrase most associated with poison ivy is “leaves of three, let it be”, which serves the purpose of both identification and an appeal for avoidance. Ironically, despite this notoriety, there is a dearth of specific knowledge about nearly all other aspects of poison ivy physiology and ecology. As a means of gaining a more molecular-oriented understanding of poison ivy physiology and ecology, Next Generation DNA sequencing technology was used to develop poison ivy root and leaf RNA-seq transcriptome resources. De novo assembled transcriptomes were analyzed to generate a core set of high quality expressed transcripts present in poison ivy tissue. The predicted protein sequences were evaluated for similarity to SwissProt homologs and InterProScan domains, as well as assigned both GO terms and KEGG annotations. Over 23,000 simple sequence repeats were identified in the transcriptome, and corresponding oligo nucleotide primer pairs were designed. A pan-transcriptome analysis of existing Anacardiaceae transcriptomes revealed conserved and unique transcripts among these species. PMID:29125533

Sequencing and De Novo Assembly of the Toxicodendron radicans (Poison Ivy) Transcriptome.

PubMed

Weisberg, Alexandra J; Kim, Gunjune; Westwood, James H; Jelesko, John G

2017-11-10

Contact with poison ivy plants is widely dreaded because they produce a natural product called urushiol that is responsible for allergenic contact delayed-dermatitis symptoms lasting for weeks. For this reason, the catchphrase most associated with poison ivy is "leaves of three, let it be", which serves the purpose of both identification and an appeal for avoidance. Ironically, despite this notoriety, there is a dearth of specific knowledge about nearly all other aspects of poison ivy physiology and ecology. As a means of gaining a more molecular-oriented understanding of poison ivy physiology and ecology, Next Generation DNA sequencing technology was used to develop poison ivy root and leaf RNA-seq transcriptome resources. De novo assembled transcriptomes were analyzed to generate a core set of high quality expressed transcripts present in poison ivy tissue. The predicted protein sequences were evaluated for similarity to SwissProt homologs and InterProScan domains, as well as assigned both GO terms and KEGG annotations. Over 23,000 simple sequence repeats were identified in the transcriptome, and corresponding oligo nucleotide primer pairs were designed. A pan-transcriptome analysis of existing Anacardiaceae transcriptomes revealed conserved and unique transcripts among these species.

Leadership Styles and Creativity: An Examination of the Four Female Ivy League Presidents

ERIC Educational Resources Information Center

Lawson-Graves, Winifert E.

2012-01-01

Increasingly, females are taking the helm as president of colleges and universities in the United States, yet men still hold the majority of presidential positions (ACE, 2012). The Ivy League is an exception. In the Ivy League, the presidency is held by an equal number of females and males. For three of four Ivy League institutions where females…

Isolation and chemical analysis of nanoparticles from English ivy (Hedera helix L.)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lenaghan, Scott C; Burris, Jason N; Chourey, Karuna

It was discovered that adventitious roots of English ivy secreted a high strength adhesive containing uniform nanoparticles. These nanoparticles were hypothesized to be organic in nature. Subsequent studies have revealed several applications for these nanoparticles, but their chemical composition remained unknown. Here, we describe an isolation procedure to obtain gram quantities of ivy nanoparticles from adventitious roots. In addition, ultraviolet/visible (UV/Vis) spectroscopy, inductively coupled plasma mass spectrometry (ICP-MS), elemental analysis, fourier transform infrared spectroscopy (FTIR), and gel electrophoresis were conducted to identify the chemical nature of the ivy nanoparticles. Based on this comprehensive analysis, we conclude that the ivy nanoparticlesmore » are proteinaceous consisting of 51.77% carbon, 4.72% nitrogen, and 0.32% sulfur, without the presence of metals. Liquid chromatography tandem mass spectrometry (LC-MS/MS) based protein profiling revealed the presence of at least 6 proteins, including heat shock proteins and other large molecular weight proteins. Identification of these protein candidates will facilitate gene discovery and bioproduction of ivy nanoparticles.« less

Germination Conditions For Poison Ivy

Treesearch

Nathan M. Schiff; Kristina F. Connor; Margaret S. Devall

2004-01-01

Several scarification and stratification treatments were tested to optimize germination conditions for poison ivy [Toxicodendron radicans (L.) Kunst]. Fall-collected seeds soaked for 1 hour in water showed increasing germination with increasing stratification. Scarification with concentrated sulphuric acid for 30 minutes resulted in approximately 65...

Microbiology of infected poison ivy dermatitis.

PubMed

Brook, I; Frazier, E H; Yeager, J K

2000-05-01

We report the aerobic and anaerobic microbiology of secondarily infected poison ivy dermatitis. The study involved retrospective review of clinical and microbiology laboratory records of patients with secondarily infected poison ivy lesions. Bacterial growth was noted in 33 specimens. Aerobic or facultative anaerobic bacteria only were present in 18 (55%) patients, anaerobic bacteria only in seven (21%), and mixed anaerobic-aerobic bacteria in eight (24%). Forty-five isolates were recovered (1.4 per specimen): 27 aerobic or facultative anaerobic bacteria, and 18 strict anaerobes. The predominant aerobic and facultative anaerobic bacteria were Staphylococcus aureus (13 isolates) and group A beta-haemolytic streptococci (six). The predominant anaerobes were Peptostreptococcus spp. (seven isolates), pigmented Prevotella and Porphyromonas spp. (four) and Fusobacterium spp. (two). Single bacterial isolates were recovered in 18 (55%) patients, eight of which were S. aureus. Nineteen of the organisms isolated from 16 (48%) patients produced the enzyme beta-lactamase. Organisms that resided in the mucous membranes close to the lesions predominated in those infections. Enteric gram-negative rods and Bacteroides fragilis group predominated in leg and buttock lesions. Group A beta-haemolytic streptococci, pigmented Prevotella and Porphyromonas and Fusobacterium spp. were most frequently recovered from lesions of the finger, face and neck. The polymicrobial aetiology of secondarily infected poison ivy lesions, and the association of bacterial flora with the anatomical site of the lesions, are demonstrated.

[Toxic contact dermatitis from poison ivy in a private garden in Germany].

PubMed

Schauder, S; Callauch, R; Hausen, B M

2006-07-01

A couple suffered for 5 years from recurrent eruptions with vesicles and bullae after contact with an unknown "climbing weed" in their private garden in Germany. After this plant was identified as poison ivy and eradicated, their skin problems were solved. This is the first report of poison ivy in this setting. Urushiols in poison ivy are not only strong allergens but also potent irritants. Negative patch tests in the husband suggest that the bullous dermatitis was a toxic reaction.

Operation IVY: 1952

DTIC Science & Technology

1982-12-01

USS Yuma had sailed from the proving ground on 8 November, before KING. During KING, Curtiss and Leo were at Kwa- "jalein, and LST-836 was at Bikini...KING Pacific Proving Ground 20. ABSTRACT (Contiru anm reywra, siate It necesaery amd identlfy by block number) IVY was a two-detonation atmospheric...in the Atomic Energy C0unmission’s (AEC) Pacific Proving Ground at Enewetak Atoll in the Marshall Islands during autumn 1952. The series consisted of

Hyposensitization to poison ivy after working in a cashew nut shell oil processing factory.

PubMed

Reginella, R F; Fairfield, J C; Marks, J G

1989-04-01

19 adults were patch tested to urushiol, the allergen in poison ivy/oak, to determine their sensitivity to this allergen after working in a cashew nut shell oil (CNSO) processing plant. The cashew nut tree and poison ivy/oak are in the same botanical family. Anacardiaceae, and they share similar chemicals which cause allergic contact dermatitis. 13 of the 19 workers had a preemployment history of poison ivy sensitivity, with 10 developing CNSO dermatitis. After working in this factory for several months, 9 of the 13 noticed a decreased sensitivity or no sensitivity to poison ivy/oak. When tested to urushiol extract, only 3 reacted positively, 2 minimally. These results imply that hyposensitization to poison ivy/oak occurred in these employees after development of hardening to cashew nut shell oil.

ALGERIAN IVY DERMATITIS—A California Disease

PubMed Central

Dorsey, Clete S.

1959-01-01

A hitherto unrecognized cause of contact dermatitis in California is the widely cultivated plant known as Algerian ivy. This plant, which grows in California (and its close relative, English ivy) causes a dermatitis which is similar to although milder than that caused by poison oak. Dermatitis from this cause occurs most frequently when persons who have become sensitive to it by previous contact trim the plant back in the spring after its seasonal spurt of growth. For persons whose occupations require repeated contact with the plant, dermatitis from this cause is an occupational hazard. Dermatitis from this plant is easily diagnosed by means of a simple patch test. In a series of 12 cases the only effective treatment was with corticosteroid agents. ImagesFigure 1.Figure 2. PMID:13629356

MALDI-MS Imaging of Urushiols in Poison Ivy Stem.

PubMed

Aziz, Mina; Sturtevant, Drew; Winston, Jordan; Collakova, Eva; Jelesko, John G; Chapman, Kent D

2017-04-29

Urushiols are the allergenic components of Toxicodendron radicans (poison ivy) as well as other Toxicodendron species. They are alk-(en)-yl catechol derivatives with a 15- or 17-carbon side chain having different degrees of unsaturation. Although several methods have been developed for analysis of urushiols in plant tissues, the in situ localization of the different urushiol congeners has not been reported. Here, we report on the first analysis of urushiols in poison ivy stems by matrix-assisted laser desorption/ionization-mass spectrometry imaging (MALDI-MSI). Our results show that the urushiol congeners with 15-carbon side chains are mainly localized to the resin ducts, while those with 17-carbon side chains are widely distributed in cortex and vascular tissues. The presence of these urushiols in stem extracts of poison ivy seedlings was confirmed by GC-MS. These novel findings provide new insights into the spatial tissue distribution of urushiols that might be biosynthetically or functionally relevant.

Ivy and neurogliaform interneurons are a major target of μ opioid receptor modulation

PubMed Central

Krook-Magnuson, Esther; Luu, Lillian; Lee, Sang-Hun; Varga, Csaba; Soltesz, Ivan

2011-01-01

Mu opioid receptors (μORs) are selectively expressed on interneurons in area CA1 of the hippocampus. Fast-spiking, parvalbumin expressing, basket cells express μORs, but circumstantial evidence suggests that another major, unidentified, GABAergic cell class must also be modulated by μORs. Here we report that the abundant, dendritically targeting, neurogliaform family of cells (Ivy and neurogliaform cells) is a previously unrecognized target of direct modulation by μORs. Ivy and neurogliaform cells are not only numerous, but also have unique properties, including promiscuous gap junctions formed with various interneuronal subtypes, volume transmission, and the ability to produce a postsynaptic GABAB response after a single presynaptic spike. Using a mouse line expressing green fluorescent protein under the neuropeptide Y promoter, we find that across all layers of CA1, activation of μORs hyperpolarizes Ivy and neurogliaform cells. Further, paired recordings between synaptically coupled Ivy and pyramidal cells show that Ivy cell terminals are dramatically inhibited by μOR-activation. Effects in Ivy and neurogliaform cells are seen at similar concentrations of agonist as those producing inhibition in fast-spiking PV basket cells. We also report that Ivy cells display the recently described phenomenon of persistent firing, a state of continued firing in the absence of continued input, and that induction of persistent firing is inhibited by μOR-activation. Together these findings identify a major, previously unrecognized, target of μOR-modulation. Given the prominence of this cell type in and beyond CA1, as well as its unique role in microcircuitry, opioid modulation of neurogliaform cells has wide implications. PMID:22016519

Ivy and neurogliaform interneurons are a major target of μ-opioid receptor modulation.

PubMed

Krook-Magnuson, Esther; Luu, Lillian; Lee, Sang-Hun; Varga, Csaba; Soltesz, Ivan

2011-10-19

μ-Opioid receptors (μORs) are selectively expressed on interneurons in area CA1 of the hippocampus. Fast-spiking, parvalbumin-expressing, basket cells express μORs, but circumstantial evidence suggests that another major, unidentified, GABAergic cell class must also be modulated by μORs. Here we report that the abundant, dendritically targeting, neurogliaform family of cells (Ivy and neurogliaform cells) is a previously unrecognized target of direct modulation by μORs. Ivy and neurogliaform cells are not only numerous but also have unique properties, including promiscuous gap junctions formed with various interneuronal subtypes, volume transmission, and the ability to produce a postsynaptic GABA(B) response after a single presynaptic spike. Using a mouse line expressing green fluorescent protein under the neuropeptide Y promoter, we find that, across all layers of CA1, activation of μORs hyperpolarizes Ivy and neurogliaform cells. Furthermore, paired recordings between synaptically coupled Ivy and pyramidal cells show that Ivy cell terminals are dramatically inhibited by μOR activation. Effects in Ivy and neurogliaform cells are seen at similar concentrations of agonist as those producing inhibition in fast-spiking parvalbumin basket cells. We also report that Ivy cells display the recently described phenomenon of persistent firing, a state of continued firing in the absence of continued input, and that induction of persistent firing is inhibited by μOR activation. Together, these findings identify a major, previously unrecognized, target of μOR modulation. Given the prominence of this cell type in and beyond CA1, as well as its unique role in microcircuitry, opioid modulation of neurogliaform cells has wide implications.

The Cultivation of Ivy. A Saga of the College in America.

ERIC Educational Resources Information Center

Thelin, John R

The popular image of the Ivy League is one of a slightly awesome bastion of the well-born, well-bred, and soon-to-be-powerful or, less charitably, a haven for "the effete, unAmerican, and hopelessly bookish." This pervasive idea of collegiate personality is analyzed, tracing the evolution of the Ivy League from an incongruous array of…

System description: IVY

DOE Office of Scientific and Technical Information (OSTI.GOV)

McCune, W.; Shumsky, O.

2000-02-04

IVY is a verified theorem prover for first-order logic with equality. It is coded in ACL2, and it makes calls to the theorem prover Otter to search for proofs and to the program MACE to search for countermodels. Verifications of Otter and MACE are not practical because they are coded in C. Instead, Otter and MACE give detailed proofs and models that are checked by verified ACL2 programs. In addition, the initial conversion to clause form is done by verified ACL2 code. The verification is done with respect to finite interpretations.

Exploring the mango-poison ivy connection: the riddle of discriminative plant dermatitis.

PubMed

Hershko, Klilah; Weinberg, Ido; Ingber, Arieh

2005-01-01

A relationship between sensitivity to poison oak or poison ivy and mango dermatitis has been suggested by previous publications. The observation that acute allergic contact dermatitis can arise on first exposure to mango in patients who have been sensitized beforehand by contact with other urushiol-containing plants has been documented previously. We report 17 American patients employed in mango picking at a summer camp in Israel, who developed a rash of varying severity. All patients were either in contact with poison ivy/oak in the past or lived in areas where these plants are endemic. None recalled previous contact with mango. In contrast, none of their Israeli companions who had never been exposed to poison ivy/oak developed mango dermatitis. These observations suggest that individuals with known history of poison ivy/oak allergy, or those residing in area where these plants are common, may develop allergic contact dermatitis from mango on first exposure. We hypothesize that previous oral exposure to urushiol in the local Israeli population might establish immune tolerance to these plants.

Nanospherical arabinogalactan proteins are a key component of the high-strength adhesive secreted by English ivy

NASA Astrophysics Data System (ADS)

Huang, Yujian; Wang, Yongzhong; Tan, Li; Sun, Leming; Petrosino, Jennifer; Cui, Mei-Zhen; Hao, Feng; Zhang, Mingjun

2016-06-01

Over 130 y have passed since Charles Darwin first discovered that the adventitious roots of English ivy (Hedera helix) exude a yellowish mucilage that promotes the capacity of this plant to climb vertical surfaces. Unfortunately, little progress has been made in elucidating the adhesion mechanisms underlying this high-strength adhesive. In the previous studies, spherical nanoparticles were observed in the viscous exudate. Here we show that these nanoparticles are predominantly composed of arabinogalactan proteins (AGPs), a superfamily of hydroxyproline-rich glycoproteins present in the extracellular spaces of plant cells. The spheroidal shape of the AGP-rich ivy nanoparticles results in a low viscosity of the ivy adhesive, and thus a favorable wetting behavior on the surface of substrates. Meanwhile, calcium-driven electrostatic interactions among carboxyl groups of the AGPs and the pectic acids give rise to the cross-linking of the exuded adhesive substances, favor subsequent curing (hardening) via formation of an adhesive film, and eventually promote the generation of mechanical interlocking between the adventitious roots of English ivy and the surface of substrates. Inspired by these molecular events, a reconstructed ivy-mimetic adhesive composite was developed by integrating purified AGP-rich ivy nanoparticles with pectic polysaccharides and calcium ions. Information gained from the subsequent tensile tests, in turn, substantiated the proposed adhesion mechanisms underlying the ivy-derived adhesive. Given that AGPs and pectic polysaccharides are also observed in bioadhesives exuded by other climbing plants, the adhesion mechanisms revealed by English ivy may forward the progress toward understanding the general principles underlying diverse botanic adhesives.

Nanospherical arabinogalactan proteins are a key component of the high-strength adhesive secreted by English ivy

PubMed Central

Huang, Yujian; Wang, Yongzhong; Tan, Li; Sun, Leming; Petrosino, Jennifer; Cui, Mei-Zhen; Hao, Feng; Zhang, Mingjun

2016-01-01

Over 130 y have passed since Charles Darwin first discovered that the adventitious roots of English ivy (Hedera helix) exude a yellowish mucilage that promotes the capacity of this plant to climb vertical surfaces. Unfortunately, little progress has been made in elucidating the adhesion mechanisms underlying this high-strength adhesive. In the previous studies, spherical nanoparticles were observed in the viscous exudate. Here we show that these nanoparticles are predominantly composed of arabinogalactan proteins (AGPs), a superfamily of hydroxyproline-rich glycoproteins present in the extracellular spaces of plant cells. The spheroidal shape of the AGP-rich ivy nanoparticles results in a low viscosity of the ivy adhesive, and thus a favorable wetting behavior on the surface of substrates. Meanwhile, calcium-driven electrostatic interactions among carboxyl groups of the AGPs and the pectic acids give rise to the cross-linking of the exuded adhesive substances, favor subsequent curing (hardening) via formation of an adhesive film, and eventually promote the generation of mechanical interlocking between the adventitious roots of English ivy and the surface of substrates. Inspired by these molecular events, a reconstructed ivy-mimetic adhesive composite was developed by integrating purified AGP-rich ivy nanoparticles with pectic polysaccharides and calcium ions. Information gained from the subsequent tensile tests, in turn, substantiated the proposed adhesion mechanisms underlying the ivy-derived adhesive. Given that AGPs and pectic polysaccharides are also observed in bioadhesives exuded by other climbing plants, the adhesion mechanisms revealed by English ivy may forward the progress toward understanding the general principles underlying diverse botanic adhesives. PMID:27217558

Plasmids for C-terminal tagging in Saccharomyces cerevisiae that contain improved GFP proteins, Envy and Ivy.

PubMed

Slubowski, Christian J; Funk, Alyssa D; Roesner, Joseph M; Paulissen, Scott M; Huang, Linda S

2015-04-01

Green fluorescent protein (GFP) has become an invaluable tool in biological research. Many GFP variants have been created that differ in brightness, photostability, and folding robustness. We have created two hybrid GFP variants, Envy and Ivy, which we placed in a vector for the C-terminal tagging of yeast proteins by PCR-mediated recombination. The Envy GFP variant combines mutations found in the robustly folding SuperfolderGFP and GFPγ, while the Ivy GFP variant is a hybrid of GFPγ and the yellow-green GFP variant, Clover. We compared Envy and Ivy to EGFP, SuperfolderGFP and GFPγ and found that Envy is brighter than the other GFP variants at both 30°C and 37°C, while Ivy is the most photostable. Envy and Ivy are recognized by a commonly used anti-GFP antibody, and both variants can be immunoprecipitated using the GFP TRAP Camelidae antibody nanotrap technology. Because Envy is brighter than the other GFP variants and is as photostable as GFPγ, we suggest that Envy should be the preferred GFP variant, while Ivy may be used in cases where photostability is of the utmost importance. Copyright © 2015 John Wiley & Sons, Ltd.

Studies on poison ivy. In vitro lymphocyte transformation by urushiol-protein conjugates.

PubMed

Dupuis, G

1979-12-01

The isolation and purification of poison ivy urushiol is described. The preparation of urushiol-ski protein and urushiol human serum albumin is also described. Lymphocytes from eleven donor naturally sensitized to poison ivy and from four non-sensitive individuals have been cultured for 5 days in the presence of urushiol-carrier conjugates. Lymphocytes from seven of the eleven sensitive donors responded with a stimulation index greater than 3.0 to urushiol-albumin conjugate. When urushiol-skin protein conjugate was used as a stimulant, lymphocytes from only three of the eleven sensitive donors responded. The results suggest that urushiol-protein conjugates can stimulate sensitive lymphocytes in vitro, although a response is not observed in every individual naturally sensitized to poison ivy.

IViPP: A Tool for Visualization in Particle Physics

NASA Astrophysics Data System (ADS)

Tran, Hieu; Skiba, Elizabeth; Baldwin, Doug

2011-10-01

Experiments and simulations in physics generate a lot of data; visualization is helpful to prepare that data for analysis. IViPP (Interactive Visualizations in Particle Physics) is an interactive computer program that visualizes results of particle physics simulations or experiments. IViPP can handle data from different simulators, such as SRIM or MCNP. It can display relevant geometry and measured scalar data; it can do simple selection from the visualized data. In order to be an effective visualization tool, IViPP must have a software architecture that can flexibly adapt to new data sources and display styles. It must be able to display complicated geometry and measured data with a high dynamic range. We therefore organize it in a highly modular structure, we develop libraries to describe geometry algorithmically, use rendering algorithms running on the powerful GPU to display 3-D geometry at interactive rates, and we represent scalar values in a visual form of scientific notation that shows both mantissa and exponent. This work was supported in part by the US Department of Energy through the Laboratory for Laser Energetics (LLE), with special thanks to Craig Sangster at LLE.

Treatment of poison ivy/oak allergic contact dermatitis with an extract of jewelweed.

PubMed

Long, D; Ballentine, N H; Marks, J G

1997-09-01

Jewelweed (Impatiens biflora) is a plant which has been used for centuries for the treatment of poison ivy/oak allergic contact dermatitis. Numerous claims for its effectiveness exist in the lay press, and over-the-counter medicaments containing jewelweed are reputed to be an effective remedy for poison ivy/oak dermatitis. Despite these claims, few scientific studies testing the effectiveness of jewelweed have been performed. Our objective in this pilot study was to test the efficacy of an extract of jewelweed in the treatment of experimentally induced allergic contact dermatitis to poison ivy/oak. A randomized, double-blinded, paired comparison investigation was performed. Ten adult volunteers were patch tested to urushiol, the allergenic resin in poison ivy/oak. For each volunteer, one patch test site was treated with an extract prepared from the fresh stems of jewelweed; the remaining site was treated with distilled water to serve as a control. Sites were examined on days 2, 3, 7, and 9 with reactions graded on a numerical scale. All subjects developed dermatitis at each patch test site. There was no statistically significant difference in the objective scores at the sites treated with jewelweed extract versus the distilled water control sites. This study demonstrated that an extract of jewelweed was not effective in the treatment of poison ivy/oak allergic contact dermatitis.

Nonenzymic spectrophotometric determination of potential poison ivy cross-reactors.

PubMed

Quattrone, A J

1977-03-01

I describe an inexpensive, nonenzymic analytical system for prescreening substances that might cross-react as Rhus toxing (e.g., poison ivy, poison oak, and sumac allergens) on human skin. By spectrophotometric assay after incubation with an oxidizing mixture of Cu(II)ammine complex and ammonium persulfate, I could accurately and reproducibly determine o-quinoidal products of several potential synthetic cross-reactors and native poison ivy allergen, and could distinguish these from catecholamines, resorcinol, p-hydroquinone, and a closely related phenol. A good correlation was obtained between this nonenzymic technique and an enzymic assay. This Cu(II)ammine/persulfate oxidative assay, however, is inexpensive and obviates any spectral interference from enzymic proteins.

Prevention of poison ivy and poison oak allergic contact dermatitis by quaternium-18 bentonite.

PubMed

Marks, J G; Fowler, J F; Sheretz, E F; Rietschel, R L

1995-08-01

Poison ivy and poison oak are the most common causes of allergic contact dermatitis in North America. We investigated whether a new topical lotion containing 5% quaternium-18 bentonite prevents experimentally induced poison ivy and poison oak allergic contact dermatitis. A single-blind, paired comparison, randomized, multicenter investigation was used to evaluate the effectiveness and safety of quaternium-18 bentonite lotion in preventing experimentally induced poison ivy and poison oak allergic contact dermatitis in susceptible volunteers. One hour before both forearms were patch tested with urushiol, the allergenic resin from poison ivy and poison oak, 5% quaternium-18 bentonite lotion was applied on one forearm. The test patches were removed after 4 hours and the sites interpreted for reaction 2, 5, and 8 days later. The difference in reactions between treated and untreated patch test sites was statistically analyzed. Two hundred eleven subjects with a history of allergic contact dermatitis to poison ivy and poison oak were studied. One hundred forty-four subjects had positive reactions to urushiol. The test sites pretreated with quaternium-18 bentonite lotion had absent or significantly reduced reactions to the urushiol compared with untreated control sites (p < 0.0001) on all test days. When it occurred, the reaction consistently appeared later on treated than on control sites (p < 0.0001). One occurrence of mild, transient erythema at the application site was the only side effect from the quaternium-18 bentonite lotion. Quaternium-18 bentonite lotion was effective in preventing or diminishing experimentally produced poison ivy and poison oak allergic contact dermatitis.

Whole-Genome Sequence and Classification of 11 Endophytic Bacteria from Poison Ivy (Toxicodendron radicans)

PubMed Central

Tran, Phuong N.; Tan, Nicholas E. H.; Lee, Yin Peng; Gan, Han Ming; Polter, Steven J.; Dailey, Lucas K.; Hudson, André O.

2015-01-01

Here, we report the whole-genome sequences and annotation of 11 endophytic bacteria from poison ivy (Toxicodendron radicans) vine tissue. Five bacteria belong to the genus Pseudomonas, and six single members from other genera were found present in interior vine tissue of poison ivy. PMID:26586879

Determination of saponins and flavonoids in ivy leaf extracts using HPLC-DAD.

PubMed

Yu, Miao; Shin, Young June; Kim, Nanyoung; Yoo, Guijae; Park, SeonJu; Kim, Seung Hyun

2015-04-01

A new method for the determination of six compounds, chlorogenic acid, rutin, nicotiflorin, hederacoside C, hederasaponin B and α-hederin, in ivy leaf extracts using high-performance liquid chromatography with diode array detector was developed. The chromatographic separation was performed on a YMC Hydrosphere C18 analytical column using a gradient elution of 0.1% phosphoric acid and acetonitrile. The method was validated in terms of specificity, linearity (r(2) > 0.9999), precision [relative standard deviation (RSD) < 0.36%] and accuracy (97.4-103.8%). The limit of detection and limit of quantification were <20.32 and 61.56 ng for all analytes, respectively. The tested compounds were found to be stable in the ivy leaf extract from 0 to 48 h, and the RSD value for each compound was <0.90%. The validated method was successfully applied to quantify all six compounds in a 30% ethanol ivy leaf extract and 13 ivy leaf extract products. The results showed that all the tested products satisfied the minimum requirement for the content of hederacoside C. However, there were some differences between the contents of other constituents. © The Author 2014. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Whole-Genome Sequence and Classification of 11 Endophytic Bacteria from Poison Ivy (Toxicodendron radicans).

PubMed

Tran, Phuong N; Tan, Nicholas E H; Lee, Yin Peng; Gan, Han Ming; Polter, Steven J; Dailey, Lucas K; Hudson, André O; Savka, Michael A

2015-11-19

Here, we report the whole-genome sequences and annotation of 11 endophytic bacteria from poison ivy (Toxicodendron radicans) vine tissue. Five bacteria belong to the genus Pseudomonas, and six single members from other genera were found present in interior vine tissue of poison ivy. Copyright © 2015 Tran et al.

Evaluating the influence of ivy canopy cover on brickwork: A case study from Warnham, West Sussex, UK

NASA Astrophysics Data System (ADS)

Coombes, Martin; Viles, Heather

2014-05-01

Biogeomorphological understanding is becoming increasingly applied in a range of environmental management contexts. The concept of 'bioprotection' is of particular relevance in the built environment. Here, the influence of higher plants on the condition of buildings and building materials, particularly vulnerable historic structures, is of great interest for conservationists and managing authorities tasked with preserving built cultural heritage. Ivy (Hedera spp.) is a widespread and prolific creeping and climbing plant that is commonly found on built structures. Opinion varies as to whether ivy is good or bad for buildings, but there is evidence to suggest it can have both protective and deteriorative influences. Here we present a case study assessment of ivy removal from a brick and mortar wall (c.100 years old) in West Sussex, UK. Using measurements of hardness (Equotip L), moisture (protimeter %WME) and visual inspection we find that the condition of brickwork varied with ivy canopy cover extent, but that this effect was not consistent between different heights on the wall. The roles of ivy in moderating wall moisture dynamics is discussed as a possible contributing factor.

Recognizing the Toxicodendrons (poison ivy, poison oak, and poison sumac).

PubMed

Guin, J D; Gillis, W T; Beaman, J H

1981-01-01

Poison ivy, poison oak, and poison sumac are now classified in the genus Toxicodendron which is readily distinguished from Rhus. In the United States, there are two species of poison oak, Toxicodendron diversilobum (western poison oak) and Toxicodendron toxicarium (eastern poison oak). There are also two species of poison ivy, Toxicodendron rydbergii, a nonclimbing subshrub, and Toxicodendron radicans, which may be either a shrub or a climbing vine. There are nine subspecies of T. radicans, six of which are found in the United States. One species of poison sumac, Toxicodendron vernix, occurs in the United States. Distinguishing features of these plants and characteristics that separate Toxicodendron from Rhus are outlined in the text and illustrated in color plates.

Oral hyposensitization to poison ivy and poison oak.

PubMed

Marks, J G; Trautlein, J J; Epstein, W L; Laws, D M; Sicard, G R

1987-04-01

We evaluated the safety and efficacy of a 1:1 mixture of pentadecylcatechol (PDC) and heptadecylcatechol (HDC) diacetate in reducing hypersensitivity to poison ivy and poison oak. The study was double-blind, parallel, randomized, and placebo controlled. The 44 subjects receiving the active drug ingested a cumulative dose of 306.5 mg over a five-week period. Subsequently, 14 patients were continued on a maintenance phase, ingesting an additional 960 mg of drug. The PDC-HDC diacetate was well tolerated, with no significant side effects. Evaluation of efficacy compared poststudy and prestudy reactions to patch tests using urushiol in doses of 0.025, 0.05, 0.125, 0.25, and 0.5 micrograms applied to the forearm. The results indicated that the induction phase as well as the maintenance phase did not induce a statistically significant hyposensitivity to urushiol, and we were thus unable to decrease sensitivity to poison ivy and poison oak in humans using orally ingested PDC-HDC diacetate.

Ivy Sign on Fluid-Attenuated Inversion Recovery Images in Moyamoya Disease: Correlation with Clinical Severity and Old Brain Lesions.

PubMed

Seo, Kwon-Duk; Suh, Sang Hyun; Kim, Yong Bae; Kim, Ji Hwa; Ahn, Sung Jun; Kim, Dong-Seok; Lee, Kyung-Yul

2015-09-01

Leptomeningeal collateral, in moyamoya disease (MMD), appears as an ivy sign on fluid-attenuated inversion-recovery (FLAIR) images. There has been little investigation into the relationship between presentation of ivy signs and old brain lesions. We aimed to evaluate clinical significance of ivy signs and whether they correlate with old brain lesions and the severity of clinical symptoms in patients with MMD. FLAIR images of 83 patients were reviewed. Each cerebral hemisphere was divided into 4 regions and each region was scored based on the prominence of the ivy sign. Total ivy score (TIS) was defined as the sum of the scores from the eight regions and dominant hemispheric ivy sign (DHI) was determined by comparing the ivy scores from each hemisphere. According to the degree of ischemic symptoms, patients were classified into four subgroups: 1) nonspecific symptoms without motor weakness, 2) single transient ischemic attack (TIA), 3) recurrent TIA, or 4) complete stroke. TIS was significantly different as follows: 4.86±2.55 in patients with nonspecific symptoms, 5.89±3.10 in patients with single TIA, 9.60±3.98 in patients with recurrent TIA and 8.37±3.39 in patients with complete stroke (p=0.003). TIS associated with old lesions was significantly higher than those not associated with old lesions (9.35±4.22 vs. 7.49±3.37, p=0.032). We found a significant correlation between DHI and motor symptoms (p=0.001). Because TIS has a strong tendency with severity of ischemic motor symptom and the presence of old lesions, the ivy sign may be useful in predicting severity of disease progression.

Retrospective: Ivy Lee and the German Dye Trust.

ERIC Educational Resources Information Center

Hainsworth, Brad E.

1987-01-01

Examines the relationship between public relations trailblazer Ivy Lee and the German Dye Trust, which became an agent for the policies of Adolf Hitler. Discusses how Lee's efforts to use this relationship to persuade his contacts to influence the Nazi leadership failed because of his formal connection with this group. (JD)

Ivy Sign on Fluid-Attenuated Inversion Recovery Images in Moyamoya Disease: Correlation with Clinical Severity and Old Brain Lesions

PubMed Central

Seo, Kwon-Duk; Suh, Sang Hyun; Kim, Yong Bae; Kim, Ji Hwa; Ahn, Sung Jun; Kim, Dong-Seok

2015-01-01

Purpose Leptomeningeal collateral, in moyamoya disease (MMD), appears as an ivy sign on fluid-attenuated inversion-recovery (FLAIR) images. There has been little investigation into the relationship between presentation of ivy signs and old brain lesions. We aimed to evaluate clinical significance of ivy signs and whether they correlate with old brain lesions and the severity of clinical symptoms in patients with MMD. Materials and Methods FLAIR images of 83 patients were reviewed. Each cerebral hemisphere was divided into 4 regions and each region was scored based on the prominence of the ivy sign. Total ivy score (TIS) was defined as the sum of the scores from the eight regions and dominant hemispheric ivy sign (DHI) was determined by comparing the ivy scores from each hemisphere. According to the degree of ischemic symptoms, patients were classified into four subgroups: 1) nonspecific symptoms without motor weakness, 2) single transient ischemic attack (TIA), 3) recurrent TIA, or 4) complete stroke. Results TIS was significantly different as follows: 4.86±2.55 in patients with nonspecific symptoms, 5.89±3.10 in patients with single TIA, 9.60±3.98 in patients with recurrent TIA and 8.37±3.39 in patients with complete stroke (p=0.003). TIS associated with old lesions was significantly higher than those not associated with old lesions (9.35±4.22 vs. 7.49±3.37, p=0.032). We found a significant correlation between DHI and motor symptoms (p=0.001). Conclusion Because TIS has a strong tendency with severity of ischemic motor symptom and the presence of old lesions, the ivy sign may be useful in predicting severity of disease progression. PMID:26256975

Differential response of pitted morning glory and ivy leaf morning glory to acifluorfen, fomesafen, and lactofen

DOE Office of Scientific and Technical Information (OSTI.GOV)

Higgins, J.M.

1987-01-01

Field and laboratory investigations were conducted to examine the response of soybeans (Glycine max (L.) Merr.), pitted morning glory (Ipomoea lacunosa L.number/sup 1/ IPOLA), and ivy leaf morning glory (Ipomoea hederacea (L.) Jacq. number IPOHE) to acifluorfen, fomesafen, and lactofen. In field studies, greatest soybean injury was observed with acifluorfen and lactofen. All treatments provided 80% or greater control of pitted morning glory 15 days after treatment. Only acifluorfen and fomesafen at 0.6 kg ai ha/sup -1/ provided 80% or greater ivy leaf morning glory. The differential response of pitted morning glory and ivy leaf morning glory to these diphenylmore » ether herbicides was reflected in soybean seed yields. In laboratory studies, 71 to 84% of applied /sup 14/C-acifluorfen was not absorbed into the leaf surface of ivy leaf morning glory. Thirty-two to 46% of applied acifluorfen was recovered from the leaf surface of pitted morning glory. Sixty-four percent of applied /sup 14/C-lactofen was recovered from leaf surfaces of both morning glory species 96 h after treatment. Treated leaves of pitted morning glory contained 35 to 37% more /sup 14/C-acifluorfen than ivy leaf morning glory. Less than 28% of applied /sup 14/C-lactofen was absorbed into treated leaves of both morning glory species at 24, 48, and 96 h harvests.« less

Inheritance of the lysozyme inhibitor Ivy was an important evolutionary step by Yersinia pestis to avoid the host innate immune response.

PubMed

Derbise, Anne; Pierre, François; Merchez, Maud; Pradel, Elizabeth; Laouami, Sabrina; Ricard, Isabelle; Sirard, Jean-Claude; Fritz, Jill; Lemaître, Nadine; Akinbi, Henry; Boneca, Ivo G; Sebbane, Florent

2013-05-15

Yersinia pestis (the plague bacillus) and its ancestor, Yersinia pseudotuberculosis (which causes self-limited bowel disease), encode putative homologues of the periplasmic lysozyme inhibitor Ivy and the membrane-bound lysozyme inhibitor MliC. The involvement of both inhibitors in virulence remains subject to debate. Mutants lacking ivy and/or mliC were generated. We evaluated the mutants' ability to counter lysozyme, grow in serum, and/or counter leukocytes; to produce disease in wild-type, neutropenic, or lysozyme-deficient rodents; and to induce host inflammation. MliC was not required for lysozyme resistance and the development of plague. Deletion of ivy decreased Y. pestis' ability to counter lysozyme and polymorphonuclear neutrophils, but it did not affect the bacterium's ability to grow in serum or resist macrophages. Y. pestis lacking Ivy had attenuated virulence, unless animals were neutropenic or lysozyme deficient. The Ivy mutant induced inflammation to a degree similar to that of the parental strain. Last, Y. pseudotuberculosis did not require Ivy to counter lysozyme and for virulence. Ivy is required to counter lysozyme during infection, but its role as a virulence factor is species dependent. Our study also shows that a gene that is not necessary for the virulence of an ancestral bacterium may become essential in the emergence of a new pathogen.

Hide and Seek: Diversity in the Ivy League

ERIC Educational Resources Information Center

Pierce, Yolanda

2005-01-01

The New York Times recently published an article titled "Little Advance Is Seen in Ivies' Hiring of Minorities and Women." The article leaves the reader with two distinct impressions: First, the pool of qualified minority scholars is just too small. And second, domestic issues make these high-powered jobs unattractive to female scholars.…

Black spot poison ivy: A report of 5 cases and a review of the literature.

PubMed

Kurlan, J G; Lucky, A W

2001-08-01

Black-spot poison ivy dermatitis is a rare manifestation of a common condition. It occurs on exposure to the resins of the plants of the Rhus family also known as Toxicodendron. We describe 5 patients with black deposits on their skin and clothing after contact with poison ivy and review the literature reflecting different aspects of this phenomenon including clinical presentation, histologic findings, and historical background.

Functional role of an endophytic Bacillus amyloliquefaciens in enhancing growth and disease protection of invasive English ivy (Hedera helix L.)

USGS Publications Warehouse

Soares, Marcos Antonio; Li, Jai-Yan; Bergen, Marshall; da Silva, Joaquim Manoel; Kowalski, Kurt P.; White, James Francis

2015-01-01

BackgroundWe hypothesize that invasive English ivy (Hedera helix) harbors endophytic microbes that promote plant growth and survival. To evaluate this hypothesis, we examined endophytic bacteria in English ivy and evaluated effects on the host plant.MethodsEndophytic bacteria were isolated from multiple populations of English ivy in New Brunswick, NJ. Bacteria were identified as a single species Bacillus amyloliquefaciens. One strain of B. amyloliquefaciens, strain C6c, was characterized for indoleacetic acid (IAA) production, secretion of hydrolytic enzymes, phosphate solubilization, and antibiosis against pathogens. PCR was used to amplify lipopeptide genes and their secretion into culture media was detected by MALDI-TOF mass spectrometry. Capability to promote growth of English ivy was evaluated in greenhouse experiments. The capacity of C6c to protect plants from disease was evaluated by exposing B+ (bacterium inoculated) and B− (non-inoculated) plants to the necrotrophic pathogen Alternaria tenuissima.ResultsB. amyloliquefaciens C6c systemically colonized leaves, petioles, and seeds of English ivy. C6c synthesized IAA and inhibited plant pathogens. MALDI-TOF mass spectrometry analysis revealed secretion of antifungal lipopeptides surfactin, iturin, bacillomycin, and fengycin. C6c promoted the growth of English ivy in low and high soil nitrogen conditions. This endophytic bacterium efficiently controlled disease caused by Alternaria tenuissima.ConclusionsThis study suggests that B. amyloliquefaciens plays an important role in enhancing growth and disease protection of English ivy.

Single dose parenteral hyposensitization to poison ivy urushiol in guinea pigs.

PubMed

Walker, L A; Watson, E S; elSohly, M A

1995-08-01

Studies were carried out in guinea pigs to evaluate the potential for single dose hyposensitization to poison ivy urushiol dermatitis. Sensitization was induced by topical application of 1 mg of poison ivy urushiol to the back of the neck. In the first series of studies, three different analogs of poison ivy urushiol were studied: 1) a mixture of pentadecyl and heptadecyl catechols (PDC/HDC), the saturated side chain analog of the natural urushiol mixture; 2) a mixture of the diacetate esters of PDC and HDC (PDC/HDC Ac), the esterified form of the saturated sidechain analogs; 3) 2-n-pentadecyl hydroquinone diacetate (HQ Ac). Each of these compounds was administered as 5 mg of the free catechol i.m. each week for three weeks. A vehicle group received only corn oil injections. Reactivity to poison ivy urushiol (PIU) challenge was evaluated in skin tests at 1 and 5 weeks post-treatment. PDC/HDC Ac induced a marked reduction in both the incidence and the severity of lesions induced by PIU at both 1 and at 5 weeks post-treatment. Other analogs were ineffective at 5 weeks post-treatment, and were less effective than PDC/HDC Ac at 1 week post-treatment. In a second series of experiments, the efficacy of PDC/HDC Ac was evaluated in both single and multiple dose regiments. One treatment group received 5 mg of PDC/HDC Ac intramuscularly each week for 4 weeks, while another treatment group received a single dose of 20 mg PDC/HDC Ac i.m. Corresponding vehicle control groups were also included. At 1 week post-treatment in the single dose group, the PDC/HDC Ac was only modestly effective, with some reduction of severity of lesions at the higher challenge doses of PIU. However, at 4 and 7 weeks post-treatment, both the incidence and the severity of the lesions at all challenge doses were reduced. In the multiple dose group, the incidence and severity of lesions are reduced at 1 week and 4 weeks post-treatment (4 weeks and 7 weeks after the initial dose) but were not significantly

Harold and Kumar Go to the Ivy League

ERIC Educational Resources Information Center

Oppenheimer, Mark

2008-01-01

For having achieved a mild cult status after doing the movie "Harold & Kumar Go to White Castle," lead actors John Cho and Kal Penn deserve their fame, their million-dollar paychecks, and their groupies. Do they deserve Ivy League teaching jobs? This spring Penn (whose real name is Kalpen Modi) taught a large lecture class, "Images of Asian…

White paper : Mn/DOT driver acceptance : IVI FOT evaluation report

DOT National Transportation Integrated Search

2003-06-30

This white paper provides findings from surveys and interviews for the evaluation of driver acceptance as a component of Battelles independent evaluation of the Mn/DOT Intelligent Vehicle Initiative (IVI) Field Operational Test (FOT), sponsored by th...

Effects and mode of action of chitosan and ivy fruit saponins on the microbiome, fermentation and methanogenesis in the rumen simulation technique.

PubMed

Belanche, Alejandro; Pinloche, Eric; Preskett, David; Newbold, C Jamie

2016-01-01

This study investigates the effects of supplementing a control diet (CON) with chitosan (CHI) or ivy fruit saponins (IVY) as natural feed additives. Both additives had similar abilities to decrease rumen methanogenesis (-42% and -40%, respectively) using different mechanisms: due to its antimicrobial and nutritional properties CHI promoted a shift in the fermentation pattern towards propionate production which explained about two thirds of the decrease in methanogenesis. This shift was achieved by a simplification of the structure in the bacterial community and a substitution of fibrolytic (Firmicutes and Fibrobacteres) by amylolytic bacteria (Bacteroidetes and Proteobacteria) which led to greater amylase activity, lactate and microbial protein yield with no detrimental effect on feed digestibility. Contrarily, IVY had negligible nutritional properties promoting minor changes in the fermentation pattern and on the bacterial community. Instead, IVY modified the structure of the methanogen community and decreased its diversity. This specific antimicrobial effect of IVY against methanogens was considered its main antimethanogenic mechanism. IVY had however a negative impact on microbial protein synthesis. Therefore, CHI and IVY should be further investigated in vivo to determine the optimum doses which maintain low methanogenesis but prevent negative effects on the rumen fermentation and animal metabolism. © FEMS 2015.

Effects and mode of action of chitosan and ivy fruit saponins on the microbiome, fermentation and methanogenesis in the rumen simulation technique

PubMed Central

Belanche, Alejandro; Pinloche, Eric; Preskett, David; Newbold, C. Jamie

2015-01-01

This study investigates the effects of supplementing a control diet (CON) with chitosan (CHI) or ivy fruit saponins (IVY) as natural feed additives. Both additives had similar abilities to decrease rumen methanogenesis (–42% and –40%, respectively) using different mechanisms: due to its antimicrobial and nutritional properties CHI promoted a shift in the fermentation pattern towards propionate production which explained about two thirds of the decrease in methanogenesis. This shift was achieved by a simplification of the structure in the bacterial community and a substitution of fibrolytic (Firmicutes and Fibrobacteres) by amylolytic bacteria (Bacteroidetes and Proteobacteria) which led to greater amylase activity, lactate and microbial protein yield with no detrimental effect on feed digestibility. Contrarily, IVY had negligible nutritional properties promoting minor changes in the fermentation pattern and on the bacterial community. Instead, IVY modified the structure of the methanogen community and decreased its diversity. This specific antimicrobial effect of IVY against methanogens was considered its main antimethanogenic mechanism. IVY had however a negative impact on microbial protein synthesis. Therefore, CHI and IVY should be further investigated in vivo to determine the optimum doses which maintain low methanogenesis but prevent negative effects on the rumen fermentation and animal metabolism. PMID:26676056

A comparison of two IPv4/IPv6 transition mechanisms - OpenVPN and IVI

NASA Astrophysics Data System (ADS)

Vu, Cong Tuan; Tran, Quang Anh; Jiang, Frank

2012-09-01

This document presents a comparison of two IPv4/IPv6 transition mechanisms. They are OpenVPN and IVI. Meanwhile OpenVPN is based on tunneling technology, IVI is a stateless IPv4/IPv6 translation technique which is developed by China Education and Research Network (CERNET). This research focus on the quantitative and qualitative comparison of these two main mechanisms; how they are applied in practical situation by the Internet Service Providers, as well as their advantages and drawbacks.

Ivy League Agrees to End Collaboration on Financial Aid.

ERIC Educational Resources Information Center

Jaschik, Scott

1991-01-01

The Ivy League colleges, formally charged with violating federal antitrust laws, agreed to stop setting joint financial-aid policies and sharing information about aid packages. The Massachusetts Institute of Technology denies violating any laws. A group of 23 prestigious institutions, the Overlap Group, have collaborated annually on financial aid.…

Black-spot poison ivy dermatitis. An acute irritant contact dermatitis superimposed upon an allergic contact dermatitis.

PubMed

Hurwitz, R M; Rivera, H P; Guin, J D

1984-08-01

A black spot in the epidermis over a blister of poison ivy dermatitis is an uncommon finding. Four patients with the phenomenon are described. Histologic and histochemical studies were made on biopsy material and the blackish deposit on the skin surface was compared with black deposits in and on leaves of the species of poison ivy. This examination revealed a yellow, amorphous substance on the stratum corneum of the lesions and a similar substance in and on leaves of the poison ivy plant, Toxicodendron radicans ssp. negundo. Associated with the pigmentary deposits there were distinct changes of acute irritant contact dermatitis superimposed upon allergic contact dermatitis. Our findings support the view that the black material is the oleoresin of the plant, and that this substance behaves both as an irritant and an allergen.

Treatment of severe poison ivy: a randomized, controlled trial of long versus short course oral prednisone.

PubMed

Curtis, Gabrielle; Lewis, Amy C

2014-12-01

Toxidendron (poison ivy, oak, and sumac) contact dermatitis is a common complaint in the outpatient primary care setting with little evidence-based guidance on best treatment duration. This randomized, controlled trial examined the efficacy and side effects of a 5-day regimen of 40 mg oral prednisone daily (short course) compared to the same 5-day regimen followed by a prednisone taper of 30 mg daily for 2 days, 20 mg daily for 2 days, 10 mg daily for 2 days, and 5 mg daily for 4 days over a total of 15 days (long course) in patients with severe poison ivy dermatitis. In 49 patients with severe poison ivy, non-adherence rates, rash return, medication side effects, and time to improvement and complete healing of the rash were not significantly different between the two groups. Patients receiving the long course regimen were significantly less likely to utilize other medications (22.7% vs. 55.6%, P = 0.02, number needed to treat 3.05). This study suggests that a longer course prescription may save patients' time and exposure to excess medication in the treatment of severe poison ivy. Application of this information to clinical practice will save return visits and reduce excess non-prescription medication administration to individual patients.

Treatment of Severe Poison Ivy: A Randomized, Controlled Trial of Long Versus Short Course Oral Prednisone

PubMed Central

Curtis, Gabrielle; Lewis, Amy C.

2014-01-01

Background Toxidendron (poison ivy, oak, and sumac) contact dermatitis is a common complaint in the outpatient primary care setting with little evidence-based guidance on best treatment duration. Methods This randomized, controlled trial examined the efficacy and side effects of a 5-day regimen of 40 mg oral prednisone daily (short course) compared to the same 5-day regimen followed by a prednisone taper of 30 mg daily for 2 days, 20 mg daily for 2 days, 10 mg daily for 2 days, and 5 mg daily for 4 days over a total of 15 days (long course) in patients with severe poison ivy dermatitis. Results In 49 patients with severe poison ivy, non-adherence rates, rash return, medication side effects, and time to improvement and complete healing of the rash were not significantly different between the two groups. Patients receiving the long course regimen were significantly less likely to utilize other medications (22.7% vs. 55.6%, P = 0.02, number needed to treat 3.05). Conclusions This study suggests that a longer course prescription may save patients’ time and exposure to excess medication in the treatment of severe poison ivy. Application of this information to clinical practice will save return visits and reduce excess non-prescription medication administration to individual patients. PMID:25247016

Treatment of toxicodendron dermatitis (poison ivy and poison oak).

PubMed

Guin, J D

2001-04-01

Toxicodendron dermatitis results from a reaction to an oil soluble oleoresin that is present in many parts of the poison ivy and poison oak plants. Prophylactic measures include avoidance, protective clothing, barrier creams and hyposensitization. Treatments include washing the area immediately with a solvent suitable for lipids and the use of anti-inflammatory agents, especially corticosteroids.

IL-33/ST2 signaling excites sensory neurons and mediates itch response in a mouse model of poison ivy contact allergy.

PubMed

Liu, Boyi; Tai, Yan; Achanta, Satyanarayana; Kaelberer, Melanie M; Caceres, Ana I; Shao, Xiaomei; Fang, Jianqiao; Jordt, Sven-Eric

2016-11-22

Poison ivy-induced allergic contact dermatitis (ACD) is the most common environmental allergic condition in the United States. Case numbers of poison ivy ACD are increasing due to growing biomass and geographical expansion of poison ivy and increasing content of the allergen, urushiol, likely attributable to rising atmospheric CO 2 Severe and treatment-resistant itch is the major complaint of affected patients. However, because of limited clinical data and poorly characterized models, the pruritic mechanisms in poison ivy ACD remain unknown. Here, we aim to identify the mechanisms of itch in a mouse model of poison ivy ACD by transcriptomics, neuronal imaging, and behavioral analysis. Using transcriptome microarray analysis, we identified IL-33 as a key cytokine up-regulated in the inflamed skin of urushiol-challenged mice. We further found that the IL-33 receptor, ST2, is expressed in small to medium-sized dorsal root ganglion (DRG) neurons, including neurons that innervate the skin. IL-33 induces Ca 2+ influx into a subset of DRG neurons through neuronal ST2. Neutralizing antibodies against IL-33 or ST2 reduced scratching behavior and skin inflammation in urushiol-challenged mice. Injection of IL-33 into urushiol-challenged skin rapidly exacerbated itch-related scratching via ST2, in a histamine-independent manner. Targeted silencing of neuronal ST2 expression by intrathecal ST2 siRNA delivery significantly attenuated pruritic responses caused by urushiol-induced ACD. These results indicate that IL-33/ST2 signaling is functionally present in primary sensory neurons and contributes to pruritus in poison ivy ACD. Blocking IL-33/ST2 signaling may represent a therapeutic approach to ameliorate itch and skin inflammation related to poison ivy ACD.

GLC analysis of poison ivy and poison oak urushiol components in vegetable oil preparations.

PubMed

Elsohly, M A; Turner, C E

1980-05-01

A procedure is described for the analysis of urushiol content of pharmaceutical preparations containing extracts of poison ivy (Toxicodendron radicans) and poison oak (T. diversilobum) in vegetable oils. The procedure involves extraction of the urushiols from the oily solutions using 90% methanol in water followed by GLC analysis of the extracts. Recoveries of both poison ivy and poison oak urushiols from solutions in corn oil, olive oil, sesame seed oil, and cottonseed oil were calculated. Correlation coefficients (r2) ranged from 0.97 to 1.00, and the coefficients of variations ranged from 3.08 to 7.90%.

Operation Ivy. Report to the Scientific Director. Documentary photography

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gaylord, J.L.

1985-09-01

The objective of Task Unit 9 was to record on film, both still and motion picture, the activities connected with certain events and programs of Operation Ivy. Task Unit 9 accomplished all the necessary field photography and was still in the process of editing this footage to form a completed motion-picture record at the time this report was written.

IL-33/ST2 signaling excites sensory neurons and mediates itch response in a mouse model of poison ivy contact allergy

PubMed Central

Liu, Boyi; Tai, Yan; Achanta, Satyanarayana; Kaelberer, Melanie M.; Caceres, Ana I.; Shao, Xiaomei; Fang, Jianqiao; Jordt, Sven-Eric

2016-01-01

Poison ivy-induced allergic contact dermatitis (ACD) is the most common environmental allergic condition in the United States. Case numbers of poison ivy ACD are increasing due to growing biomass and geographical expansion of poison ivy and increasing content of the allergen, urushiol, likely attributable to rising atmospheric CO2. Severe and treatment-resistant itch is the major complaint of affected patients. However, because of limited clinical data and poorly characterized models, the pruritic mechanisms in poison ivy ACD remain unknown. Here, we aim to identify the mechanisms of itch in a mouse model of poison ivy ACD by transcriptomics, neuronal imaging, and behavioral analysis. Using transcriptome microarray analysis, we identified IL-33 as a key cytokine up-regulated in the inflamed skin of urushiol-challenged mice. We further found that the IL-33 receptor, ST2, is expressed in small to medium-sized dorsal root ganglion (DRG) neurons, including neurons that innervate the skin. IL-33 induces Ca2+ influx into a subset of DRG neurons through neuronal ST2. Neutralizing antibodies against IL-33 or ST2 reduced scratching behavior and skin inflammation in urushiol-challenged mice. Injection of IL-33 into urushiol-challenged skin rapidly exacerbated itch-related scratching via ST2, in a histamine-independent manner. Targeted silencing of neuronal ST2 expression by intrathecal ST2 siRNA delivery significantly attenuated pruritic responses caused by urushiol-induced ACD. These results indicate that IL-33/ST2 signaling is functionally present in primary sensory neurons and contributes to pruritus in poison ivy ACD. Blocking IL-33/ST2 signaling may represent a therapeutic approach to ameliorate itch and skin inflammation related to poison ivy ACD. PMID:27821781

Problem area descriptions : motor vehicle crashes - data analysis and IVI program analysis

DOT National Transportation Integrated Search

In general, the IVI program focuses on the more significant safety problem categories as : indicated by statistical analyses of crash data. However, other factors were considered in setting : program priorities and schedules. For some problem areas, ...

[Contact allergy caused by poison ivy (Toxicodendron spp].

PubMed

Fölster-Holst, R; Hausen, B M; Brasch, J; Christophers, E

2001-02-01

Within 3 days two female patients presented with an eruption featuring erythema, edema, vesicles and bullae. We suspected poison ivy allergy which was subsequently proven by history and positive patch tests. In Germany the risk of specific hypersensitivity to Toxicodendron species is low, since the distribution of such plants is confined to botanical gardens. Other species belonging to the family of Anacardiaceae contain urushiols as well (e.g., mango, cashew) and may cause allergic contact dermatitis.

New GLC analysis of urushiol congeners in different plant parts of poison ivy, Toxicodendron radicans.

PubMed

Craig, J C; Waller, C W; Billets, S; Elsohly, M A

1978-04-01

Methods are presented for the direct GLC analysis of the catechol C15 alkenyl side-chain congeners contained in the urushiol fraction of poison ivy (Toxicodendron radicans) and the C17 homologs of poison oak (Toxicodendron diversilobum). A number of liquid phases were investigated and demonstrated varying degrees of separation. The methods developed were applied to the analysis of the urushiol fractions obtained from different plant parts of poison ivy. The effects of extraction before and after drying demonstrated tht a larger percentage of urushiol was obtained when the fresh plant material was extracted with ethanol.

Biology and host range of the moth Digitivalva delaireae as one of two candidate agents for biological control of Cape-ivy

USDA-ARS?s Scientific Manuscript database

Cape-ivy (Delairea odorata, Asteraceae), native to coastal floodplains and mountains in eastern South Africa, is an invasive vine in coastal riparian, woodland and scrub habitats in California and southern Oregon, as well as mid-elevation regions on some of the Hawaiian Islands. Cape-ivy smothers na...

Biomass and toxicity responses of poison ivy (Toxicodendron radicans) to elevated atmospheric CO2.

PubMed

Mohan, Jacqueline E; Ziska, Lewis H; Schlesinger, William H; Thomas, Richard B; Sicher, Richard C; George, Kate; Clark, James S

2006-06-13

Contact with poison ivy (Toxicodendron radicans) is one of the most widely reported ailments at poison centers in the United States, and this plant has been introduced throughout the world, where it occurs with other allergenic members of the cashew family (Anacardiaceae). Approximately 80% of humans develop dermatitis upon exposure to the carbon-based active compound, urushiol. It is not known how poison ivy might respond to increasing concentrations of atmospheric carbon dioxide (CO(2)), but previous work done in controlled growth chambers shows that other vines exhibit large growth enhancement from elevated CO(2). Rising CO(2) is potentially responsible for the increased vine abundance that is inhibiting forest regeneration and increasing tree mortality around the world. In this 6-year study at the Duke University Free-Air CO(2) Enrichment experiment, we show that elevated atmospheric CO(2) in an intact forest ecosystem increases photosynthesis, water use efficiency, growth, and population biomass of poison ivy. The CO(2) growth stimulation exceeds that of most other woody species. Furthermore, high-CO(2) plants produce a more allergenic form of urushiol. Our results indicate that Toxicodendron taxa will become more abundant and more "toxic" in the future, potentially affecting global forest dynamics and human health.

Biomass and toxicity responses of poison ivy (Toxicodendron radicans) to elevated atmospheric CO2

PubMed Central

Mohan, Jacqueline E.; Ziska, Lewis H.; Schlesinger, William H.; Thomas, Richard B.; Sicher, Richard C.; George, Kate; Clark, James S.

2006-01-01

Contact with poison ivy (Toxicodendron radicans) is one of the most widely reported ailments at poison centers in the United States, and this plant has been introduced throughout the world, where it occurs with other allergenic members of the cashew family (Anacardiaceae). Approximately 80% of humans develop dermatitis upon exposure to the carbon-based active compound, urushiol. It is not known how poison ivy might respond to increasing concentrations of atmospheric carbon dioxide (CO2), but previous work done in controlled growth chambers shows that other vines exhibit large growth enhancement from elevated CO2. Rising CO2 is potentially responsible for the increased vine abundance that is inhibiting forest regeneration and increasing tree mortality around the world. In this 6-year study at the Duke University Free-Air CO2 Enrichment experiment, we show that elevated atmospheric CO2 in an intact forest ecosystem increases photosynthesis, water use efficiency, growth, and population biomass of poison ivy. The CO2 growth stimulation exceeds that of most other woody species. Furthermore, high-CO2 plants produce a more allergenic form of urushiol. Our results indicate that Toxicodendron taxa will become more abundant and more “toxic” in the future, potentially affecting global forest dynamics and human health. PMID:16754866

Erythema multiforme associated with contact dermatitis to poison ivy: three cases and a review of the literature.

PubMed

Cohen, L M; Cohen, J L

1998-09-01

Erythema multiforme (EM) is a hypersensitivity reaction that occurs mainly after exposure to certain medications or in the setting of infection, most commonly that due to herpes simplex virus. Rare cases of EM have been reported after allergic contact dermatitis due to various substances. There has been one case in the literature of EM following Rhus contact dermatitis. We report three patients who developed EM after allergic contact dermatitis due to poison ivy. In all three patients, targetoid lesions developed primarily on the palms and soles, either after a brief course of prednisone or during its taper. Two of the patients have had more than one episode of EM after poison ivy dermatitis. Although EM has been described after allergic contact dermatitis due to a variety of antigens (nickel being the most common), there is only one report in the literature of EM following Rhus contact dermatitis. Given the prevalence of allergic contact dermatitis due to poison ivy, this may be an under-reported complication.

Performance of dye-sensitized solar cells fabricated with extracts from fruits of ivy gourd and flowers of red frangipani as sensitizers

NASA Astrophysics Data System (ADS)

Shanmugam, Vinoth; Manoharan, Subbaiah; Anandan, Sambandam; Murugan, Ramaswamy

2013-03-01

Natural dyes extracted from fruits of ivy gourd and flowers of red frangipani were used as sensitizers to fabricate dye sensitized solar cells (DSSCs). The UV-Vis absorption spectroscopy, Fourier transform infrared (FTIR), Fourier transform Raman (FT-Raman) and liquid chromatography-mass spectrometry (LC-MS) studies indicated the presence of β-carotene in the fruits of ivy gourd and anthocyanins in the flowers of red frangipani. The extract of the flowers of red frangipani exhibits higher photosensitized performance compared to the fruits of ivy gourd and this is due to the better charge transfer between the dyes of flowers of red frangipani and the TiO2 photoanode surface.

Shoot growth and leaf dimorphism in Boston ivy (Parthenocissus tricuspidata)

Treesearch

William B. Critchfield

1970-01-01

Boston ivy, a common ornamental vine in the grape family, successively produces two kinds of leaves during the growing season. The two "early leaves" at the base of each shoot are preformed in the winter bud, and their expansion in the spring is accompanied by little stem elongation. At maturity they have large three-lobed blades and long petioles. Most short...

Immunologic studies of poisonous Anacardiaceae: I. Production of tolerance and desensitization to poison Ivy and oak urushiols using esterified urushiol derivatives in guinea pigs.

PubMed

Watson, E S; Murphy, J C; Wirth, P W; Waller, C W; Elsohly, M A

1981-03-01

The development of contact sensitivity to poison ivy urushiol in Hartley guinea pigs was inhibited by i.v. injection of the diacetate esters of poison ivy and oak urushiols into guinea pigs 2 weeks prior to attempted sensitization with homologous antigen. Immune tolerance to urushiols of poison ivy and oak developed in 80% or more of the treated animals and persisted for the duration of the study, 8 weeks. The tolerance was immunologically specific for urushiols since the tolerant animals were sensitizable to the unrelated sensitizer 2, 4-dinitrochlorobenzene. Guinea pigs already sensitive to urushiol were also desensitized or hyposensitizied by i.v. injection of urushiol acetates in successively increasing doses. After receiving the equivalent of 16 mg of poison ivy and oak urushiols in the acetate form over a period of 12 weeks, 54% of a group of guinea pigs were desensitized to poison ivy. all of the remaining 46% of the guinea pigs still sensitive to poison ivy were substantially hyposensitized (no longer responded to 1.5 or 0.80 microgram test doses of PDC). A control group of guinea pigs was not hyposensitized by injection of vehicle, and remained highly sensitive throughout the 15 week study. The majority of treated animals (less than 80%) were also hyposensitized to poison sumac and cashew nut shell liquid allergens.

Molecular analysis of ivy cells of the hippocampal CA1 stratum radiatum using spectral identification of immunofluorophores

PubMed Central

Somogyi, Jozsef; Szabo, Andras; Somogyi, Peter; Lamsa, Karri

2012-01-01

Neuronal nitric oxide synthase-expressing (nNOS+) GABAergic interneurons are common in hippocampal stratum (str.) radiatum. However, these cells are less well characterized than nNOS+ ivy cells in str. pyramidale or neurogliaform cells (NGC) in str. lacunosum-moleculare. Here we have studied the laminar distribution of the axons and dendrites, and the immunoreactivity of these neurons recorded in rat hippocampal slices. We have used spectral analysis of antibody- or streptavidin-conjugated fluorophores to improve recognition of genuine signals in reactions for molecules such as nNOS and neuropeptide-Y (NPY). We found that most nNOS+ cells with soma in the CA1 area str. radiatum exhibit characteristic properties of ivy cells, and were positive for NPY and negative for reelin. However, laminar distributions of their neurites differ from original characterization of ivy cells with the soma in or close to str. pyramidale. Both their dendrites and axon are mainly in str. radiatum and to a lesser extent in str. oriens, and in addition often extend to str. lacunosum-moleculare. We conclude that ivy cells in str. radiatum may predominantly be feedforward inhibitory interneurons in the CA1 area, and their axonal output delivering GABA, NPY, and NO can influence both the entorhinal cortex innervated and the CA3 innervated zones pre- and post-synaptically. Spectral analysis of fluorophores provides an objective algorithm to analyze signals in immunoreactions for neurochemical markers. PMID:22666191

Gas plant (Dictamnus albus) phytophotodermatitis simulating poison ivy.

PubMed Central

Henderson, J. A.; DesGroseilliers, J. P.

1984-01-01

A 48-year-old man presented with an itchy rash that resembled superficial burns or cane marks on his left forearm; similar lesions had appeared every summer for 5 years. Poison ivy dermatitis had been the initial diagnosis, but the patient knew that this plant was absent from his well tended garden. A visit to the garden revealed the gas plant Dictamnus albus, and occlusive patch testing with leaf cuttings produced a reaction after the skin was exposed to sunlight. Gas plant phytophotodermatitis was diagnosed. Images p889-a Fig. 1 Fig. 2 PMID:6231089

Toxicodendron dermatitis: poison ivy, oak, and sumac.

PubMed

Gladman, Aaron C

2006-01-01

Allergic contact dermatitis caused by the Toxicodendron (formerly Rhus) species-poison ivy, poison oak, and poison sumac-affects millions of North Americans every year. In certain outdoor occupations, for example, agriculture and forestry, as well as among many outdoor enthusiasts, Toxicodendron dermatitis presents a significant hazard. This review considers the epidemiology, identification, immunochemistry, pathophysiology, clinical features, treatment, and prevention of this common dermatologic problem. Recent research in prevention is emphasized, and resources to help in the identification of plants are provided in the bibliography. The literature was searched using a MEDLINE query for "Toxicodendron dermatitis", and the identified article bibliographies were searched as well.

Preservation of allergic contact dermatitis to poison ivy (urushiol) in late HIV disease. The implications and relevance to immunotherapy with contact allergens.

PubMed

Smith, K J; Skelton, H G; Nelson, A; Wagner, K F; Hackley, B E

1997-01-01

Delayed hypersensitivity reactions (DTH) are lost with progression of HIV disease. This loss of DTH commonly occurs before the onset of opportunistic infections and is an independent predictor of disease progression. We wanted to determine whether patients in late HIV disease with a history of allergic contact dermatitis (ACD) to poison ivy continue to react to poison ivy. Twelve HIV+ patients with a past history of ACD to poison ivy were tested with an extract prepared from poison ivy leaves. All but 1 patient had CD4+ T cell counts < 200/microliters, and 5 patients had had an opportunistic infection. All 12 patients showed positive reactions ranging from mild erythema and infiltration to marked erythema with bulla formation. ACD is considered a variant of DTH, and as DTH results in a T helper 1 cytokine pattern. However, the antigen-specific effector cells in ACD may be more diverse than in DTH. This diversity could explain the continued reaction to some contact allergens in late disease and may be important in the use of contact allergens for immunotherapy.

Impact of urban land use on the bacterial phyllosphere of ivy (Hedera sp.)

NASA Astrophysics Data System (ADS)

Smets, Wenke; Wuyts, Karen; Oerlemans, Eline; Wuyts, Sander; Denys, Siegfried; Samson, Roeland; Lebeer, Sarah

2016-12-01

The surface of the aerial parts of the plant, also termed the phyllosphere, is a selective habitat for microbes. The bacterial composition of the phyllosphere depends on host plant species, leaf characteristics, season, climate, and geographic location of the host plant. In this study, we investigated the effect of an urban environment on the bacterial composition of phyllosphere communities. We performed a passive biomonitoring experiment in which leaves were sampled from ivy (Hedera sp.), a common evergreen climber species, in urban and non-urban locations. Exposure to traffic-generated particulate matter was estimated using leaf biomagnetic analyses. The bacterial community composition was determined using 16S rRNA gene sequencing on the Illumina MiSeq. The phyllosphere microbial communities of ivy differed greatly between urban and non-urban locations, as we observed a shift in several of the dominant taxa: Beijerinckia and Methylocystaceae were most abundant in the non-urban phyllosphere, whereas Hymenobacter and Sphingomonadaceae were dominating the urban ivy phyllosphere. The richness, diversity and composition of the communities showed greater variability in the urban than in the non-urban locations, where traffic-generated PM was lower. Interestingly, the relative abundances of eight of the ten most dominant taxa correlated well with leaf magnetism, be it positive or negative. The results of this study indicate that an urban environment can greatly affect the local phyllosphere community composition. Although other urban-related factors cannot be ruled out, the relative abundance of most of the dominant taxa was significantly correlated with exposure to traffic-generated PM.

Discussing the Issues: A Report on the 2013 Ivies + Access Services Symposium

ERIC Educational Resources Information Center

Wilson, Andrew M.

2014-01-01

As access services emerges as a discrete discipline within the field of librarianship, opportunities for access services librarians to meet and discuss the issues facing today's libraries continue to grow. One annual meeting that has attracted less attention over the years is the Ivies + Access Services Symposium. Held at various member…

efficacy of dry extract of ivy leaves in the treatment of productive cough.

PubMed

Schönknecht, Karina; Fal, Andrzej M; Mastalerz-Migas, Agnieszka; Joachimiak, Monika; Doniec, Zbigniew

Introduction: Coughing is a physiological, spontaneous defense mechanism against irritants that stimulate respiratory mucosa. Productive cough should be not suppressed; instead, mucus-dissolving agents are recommended. One of the expectorants, which increases the excretion volume, is the herbal medicine derived from ivy leaves. The ivy extract contains triterpene saponins, which have secretory properties. The aim of this study was to determine the effectiveness and safety of the treatment with the medicinal product Hedussin®, containing dry ivy extract, in the therapy of productive cough in the course of the respiratory tract infection. Material and methods:This was a non-randomized, non-interventional, multicenter, open-label, post-authorization effectiveness study (PAES). The study group consisted of 464 patients aged 2-12 years with productive cough. The study was supported by a questionnaire that included: the type of cough etiological factor, Bronchitis Severity Score (BSS), temperature, and prescription of antibiotic therapy. Effectiveness and safety of the therapy with Hedussin® was assessed at the follow-up visit. Results and conclusion: Improvement in cough was reported in 93.3% subjects; improvement in chest pain on coughing was reported in 84.7%, in wheezing - in 90.0%, in dyspnoea - in 88.7%, and in auscultation changes - in 94.8%. In addition, decline or normalization of body temperature was found in 96.0% of subjects. No adverse drug reactions were reported in the study population. The non-antibiotic treated group showed similar proportions. The results of this study support the efficacy of Hedussin® prescribed for the treatment of productive cough in the course of respiratory tract infections. Hedussin® was well tolerated by sick children aged 2-12 years.

In-Vehicle Information Systems Behavioral Model and Design Support: IVIS Demand Prototype Software User's Manual

DOT National Transportation Integrated Search

2000-03-06

The purpose of this research was to develop a behavioral model and prototype computer program for evaluation of modern in-vehicle information systems (IVIS). These systems differ from earlier in-vehicle instruments and displays in that they may requi...

Yeast Ivy1p Is a Putative I-BAR-domain Protein with pH-sensitive Filament Forming Ability in vitro.

PubMed

Itoh, Yuzuru; Kida, Kazuki; Hanawa-Suetsugu, Kyoko; Suetsugu, Shiro

2016-01-01

Bin-Amphiphysin-Rvs161/167 (BAR) domains mold lipid bilayer membranes into tubules, by forming a spiral polymer on the membrane. Most BAR domains are thought to be involved in forming membrane invaginations through their concave membrane binding surfaces, whereas some members have convex membrane binding surfaces, and thereby mold membranes into protrusions. The BAR domains with a convex surface form a subtype called the inverse BAR (I-BAR) domain or IRSp53-MIM-homology domain (IMD). Although the mammalian I-BAR domains have been studied, those from other organisms remain elusive. Here, we found putative I-BAR domains in Fungi and animal-like unicellular organisms. The fungal protein containing the putative I-BAR-domain is known as Ivy1p in yeast, and is reportedly localized in the vacuole. The phylogenetic analysis of the I-BAR domains revealed that the fungal I-BAR-domain containing proteins comprise a distinct group from those containing IRSp53 or MIM. Importantly, Ivy1p formed a polymer with a diameter of approximately 20 nm in vitro, without a lipid membrane. The filaments were formed at neutral pH, but disassembled when pH was reverted to basic. Moreover, Ivy1p and the I-BAR domain expressed in mammalian HeLa cells was localized at a vacuole-like structure as filaments as revealed by super-resolved microscopy. These data indicate the pH-sensitive polymer forming ability and the functional conservation of Ivy1p in eukaryotic cells.

Poison ivy, oak, and sumac dermatitis identification, treatment, and prevention.

PubMed

Garner, L A

1999-05-01

Allergic contact dermatitis from poison ivy, oak, or sumac is common among people who work or exercise outdoors. The plants, classified in the genus Rhus or Toxicodendron, contain allergens that can cause reactions ranging from mild pruritus to severe urticaria or generalized maculopapular eruptions. Initial management includes cleansing, cold compresses, and, possibly, oral antihistamines for symptomatic relief. Topical corticosteroids are given for localized nonfacial eruptions; systemic corticosteroids are used for severe eruptions. Prevention involves avoiding contact with the plants and washing exposed skin within 2 hours.

Poison ivy/oak dermatitis. Use of polyamine salts of a linoleic acid dimer for topical prophylaxis.

PubMed

Orchard, S; Fellman, J H; Storrs, F J

1986-07-01

Closed patch tests were used to evaluate the ability of 156 different preparations (based on 22 different chemicals) to prevent poison ivy dermatitis. Several polyamine salts of a linoleic acid dimer were identified that were totally able to prevent the usual dermatitis in approximately 70% of subjects. The effectiveness of the preparations improved when the antigen and the protectant were washed off within eight to 12 hours, instead of remaining on the skin for 48 hours. When washed off, and depending on the protectant, concentration, and vehicle used, several of the preparations were totally able to prevent a dermatitis in a range of 56% to 100% of subjects tested. Further work with these compounds may greatly benefit the many people currently plagued by their allergy to poison ivy and poison oak.

Performance Evaluation of an Intel Haswell- and Ivy Bridge-Based Supercomputer Using Scientific and Engineering Applications

NASA Technical Reports Server (NTRS)

Saini, Subhash; Hood, Robert T.; Chang, Johnny; Baron, John

2016-01-01

We present a performance evaluation conducted on a production supercomputer of the Intel Xeon Processor E5- 2680v3, a twelve-core implementation of the fourth-generation Haswell architecture, and compare it with Intel Xeon Processor E5-2680v2, an Ivy Bridge implementation of the third-generation Sandy Bridge architecture. Several new architectural features have been incorporated in Haswell including improvements in all levels of the memory hierarchy as well as improvements to vector instructions and power management. We critically evaluate these new features of Haswell and compare with Ivy Bridge using several low-level benchmarks including subset of HPCC, HPCG and four full-scale scientific and engineering applications. We also present a model to predict the performance of HPCG and Cart3D within 5%, and Overflow within 10% accuracy.

[Contact allergy to Anacardiaceae. A review and case reports of poison ivy allergy in central Europe].

PubMed

Ippen, H

1983-01-01

In Europe, as opposed to North America, poison-ivy rash is hardly known. For this reason a detailed review of the allergenic members of the Anacardiaceae family is given, and the misleading nomenclature of "poison ivy", "poison oak", and some other species of this family are discussed. An up-to-date representation of the chemical structure of the allergenic substance group (denoted as "Urushiol") from this family is provided as well as botanical information regarding the plants themselves. Prevention of this dangerous sensitization and the therapy of this allergic reaction are discussed. The four cases presented are as follows: a young German woman who became sensitized to poison ivy or poison oak while in the USA and showed a cross reaction to other Rhus species (R. copallina, R. javanica (semialata), R. trichocarpa) as well as to Choerospondias axillaris var. japonica and to mangoes; a landscape gardener with an occupationally acquired allergy to Anacardium occidentale; and two control persons giving positive results to skin tests with Urushiol and Rhus trichocarpa respectively, to which the source of sensitization could not be clarified. Tests with three kinds of pistachio and two native-European Anacardiaceae (Rhus typhina and Cotinus coggygria) yielded negative results in each case. Prophylaxis to sensitization requires familiarity with the numerous Anacardiaceae and derivative products to which one could come in contact. These substances, summarized in a table, include mango, cashew and "sweet pepper".

In-vehicle Information Systems Behavioral Model and Design Support: IVIS Demand Prototype Software User’s Manual

DOT National Transportation Integrated Search

2000-03-06

The purpose of this research was to develop a behavioral model and prototype computer program for evaluation of modern in-vehicle information systems (IVIS). These systems differ from earlier in-vehicle instruments and displays in that they may requi...

THE RELATION OF CHEMICAL STRUCTURE IN CATECHOL COMPOUNDS AND DERIVATIVES TO POISON IVY HYPERSENSITIVENESS IN MAN AS SHOWN BY THE PATCH TEST

PubMed Central

Keil, Harry; Wasserman, David; Dawson, Charles R.

1944-01-01

1. Additional evidence is presented in support of the view which postulates a close chemical and biologic relation between the active ingredients in poison ivy and Japan lac. 2. Biologic evidence, based on the use of the patch test in man, is presented in support of the view that the active ingredient in poison ivy is a catechol derivative with a long, unsaturated side-chain in the 3-position. 3. Of the catechol compounds and derivatives studied, group reactions in patients sensitive to poison ivy leaves or extract were exhibited by the following compounds: 3-pentadecyl catechol (100 per cent of 21 cases), 4-pentadecyl catechol (38 per cent of 21 cases), "urushiol" dimethyl ether (33 per cent of 33 cases), 3-pentadecenyl-1'-veratrole (21 per cent of 14 cases), 3-methyl catechol (14 per cent of 21 cases), and hydrourushiol dimethyl ether (10 per cent of 20 cases). It has been found that 3-geranyl catechol shows a practically constant group reactivity in persons sensitive to poison ivy. 4. The uniformly positive group reaction to 3-pentadecyl catechol is notable since this substance possesses a saturated side-chain, whereas the active ingredient in poison ivy is known to have an unsaturated side-chain. 5. The group reactivity was not restricted to the 3-position, for in some instances 4-pentadecyl catechol also gave group reactions which, however, were less intense and less frequent than those shown by 3-pentadecyl catechol. This indicates that in some cases a long side-chain in the 4 position may be effective in producing group specific reactions. 6. Only an occasional person showed sensitiveness to 3-methyl catechol (short side-chain), and in one instance the group reactivity appeared to be specific for the 3-position. 7. The position of the side-chain in the catechol configuration has some bearing on the degree and incidence of group reactions in persons hypersensitive to poison ivy. 8. Evidence is presented to indicate that the introduction of double bonds in the

THE RELATION OF CHEMICAL STRUCTURE IN CATECHOL COMPOUNDS AND DERIVATIVES TO POISON IVY HYPERSENSITIVENESS IN MAN AS SHOWN BY THE PATCH TEST.

PubMed

Keil, H; Wasserman, D; Dawson, C R

1944-10-01

1. Additional evidence is presented in support of the view which postulates a close chemical and biologic relation between the active ingredients in poison ivy and Japan lac. 2. Biologic evidence, based on the use of the patch test in man, is presented in support of the view that the active ingredient in poison ivy is a catechol derivative with a long, unsaturated side-chain in the 3-position. 3. Of the catechol compounds and derivatives studied, group reactions in patients sensitive to poison ivy leaves or extract were exhibited by the following compounds: 3-pentadecyl catechol (100 per cent of 21 cases), 4-pentadecyl catechol (38 per cent of 21 cases), "urushiol" dimethyl ether (33 per cent of 33 cases), 3-pentadecenyl-1'-veratrole (21 per cent of 14 cases), 3-methyl catechol (14 per cent of 21 cases), and hydrourushiol dimethyl ether (10 per cent of 20 cases). It has been found that 3-geranyl catechol shows a practically constant group reactivity in persons sensitive to poison ivy. 4. The uniformly positive group reaction to 3-pentadecyl catechol is notable since this substance possesses a saturated side-chain, whereas the active ingredient in poison ivy is known to have an unsaturated side-chain. 5. The group reactivity was not restricted to the 3-position, for in some instances 4-pentadecyl catechol also gave group reactions which, however, were less intense and less frequent than those shown by 3-pentadecyl catechol. This indicates that in some cases a long side-chain in the 4 position may be effective in producing group specific reactions. 6. Only an occasional person showed sensitiveness to 3-methyl catechol (short side-chain), and in one instance the group reactivity appeared to be specific for the 3-position. 7. The position of the side-chain in the catechol configuration has some bearing on the degree and incidence of group reactions in persons hypersensitive to poison ivy. 8. Evidence is presented to indicate that the introduction of double bonds in the

The effectiveness of jewelweed, Impatiens capensis, the related cultivar I. balsamina and the component, lawsone in preventing post poison ivy exposure contact dermatitis.

PubMed

Abrams Motz, Vicki; Bowers, Christopher P; Mull Young, Linda; Kinder, David H

2012-08-30

Impatiens capensis (jewelweed) is native to the Eastern and Midwestern US and Canada. Many Native American tribes used I. capensis and its close relatives to treat/prevent rash from plant sources particularly Toxicodendron radicans and Urtica dioica. I. balsamina (garden balsam) a native of China was used by the indigenous people of Asia for similar purposes. This study aims to validate ethnopharmacological use of jewelweed in poison ivy (PI) dermatitis prevention and to refute scientific papers denying this efficacy. Additionally, the content of lawsone, the purported effective agent in jewelweed preparations, was measured to see if its concentration correlated with jewelweed preparation efficacy. Poison ivy was brushed onto forearms of volunteers in 6 locations and exposed areas were treated with jewelweed extracts, fresh plant mashes, soaps made of plant extracts, water and Dawn® dish soap. Rash development was scored on a scale of 0-14. Jewelweed mash was effective in reducing poison ivy dermatitis, supporting ethnobotanical use. However, jewelweed extracts were not effective; and soaps made of these extracts were effective but no more so than jewelweed-free soaps. Lawsone content varied with harvest season and did not appear to affect rash development. Jewelweed is an efficacious plant for preventing development of dermatitis following poison ivy contact, but soap is more effective. Lawsone content does not correlate with PI rash prevention. Perhaps saponins, the soapy component of jewelweed are the effective agents. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

Induction of tolerance to poison ivy urushiol in the guinea pig by epicutaneous application of the structural analog 5-methyl-3-n-pentadecylcatechol.

PubMed

Stampf, J L; Benezra, C; Byers, V; Castagnoli, N

1986-05-01

Previous studies have established that epicutaneous application of 5-methyl-3-n-pentadecylcatechol (5-Me-PDC), a synthetic analog of a poison ivy urushiol component, leads to immune tolerance to 3-n-pentadecylcatechol (PDC) in mice. The induction of tolerance by 5-Me-PDC may be mediated by a protein conjugate formed via selective reaction of thiol nucleophiles present on the carrier macromolecule with the corresponding o-quinone derived from the parent catechol. In order to examine further the tolerogenic properties of 5-Me-PDC, we have extended our studies to the guinea pig, the generally accepted experimental species for the study of contact allergy. The results have established that specific immune tolerance to poison ivy urushiol is induced following 2 epicutaneous applications of the PDC analog. Furthermore, we were able to show that the treated animals remained tolerant for at least 6 weeks, a period of time comparable to that observed following the intravenous administration of the O,O-bis-acetyl derivative of PDC. The data point to the possibility of developing a therapeutically effective topical tolerogen for poison ivy contact dermatitis.

Phylogenetic and paleobotanical evidence for late Miocene diversification of the Tertiary subtropical lineage of ivies (Hedera L., Araliaceae).

PubMed

Valcárcel, V; Guzmán, B; Medina, N G; Vargas, P; Wen, J

2017-06-22

Hedera (ivies) is one of the few temperate genera of the primarily tropical Asian Palmate group of the Araliaceae, which extends its range out of Asia to Europe and the Mediterranean basin. Phylogenetic and phylogeographic results suggested Asia as the center of origin and the western Mediterranean region as one of the secondary centers of diversification. The bird-dispersed fleshy fruits of ivies suggest frequent dispersal over long distances (e.g. Macaronesian archipelagos), although reducing the impact of geographic barriers to gene flow in mainland species. Genetic isolation associated with geographic barriers and independent polyploidization events have been postulated as the main driving forces of diversification. In this study we aim to evaluate past and present diversification patterns in Hedera within a geographic and temporal framework to clarify the biogeographic history of the genus. Phylogenetic (biogeographic, time divergence and diversification) and phylogeographic (coalescence) analyses using four DNA regions (nrITS, trnH-psbA, trnT-trnL, rpl32) revealed a complex spatial pattern of lineage divergence. Scarce geographic limitation to gene flow and limited diversification are observed during the early-mid Miocene, followed by a diversification rate increase related to geographic divergence from the Tortonian/Messinian. Genetic and palaeobotanical evidence points the origin of the Hedera clade in Asia, followed by a gradual E-W Asian extinction and the progressive E-W Mediterranean colonization. The temporal framework for the E Asia - W Mediterranean westward colonization herein reported is congruent with the fossil record. Subsequent range expansion in Europe and back colonization to Asia is also inferred. Uneven diversification among geographic areas occurred from the Tortonian/Messinian onwards with limited diversification in the newly colonized European and Asian regions. Eastern and western Mediterranean regions acted as refugia for Miocene and

The usefulness of the ivy sign on fluid-attenuated intensity recovery images in improved brain hemodynamic changes after superficial temporal artery-middle cerebral artery anastomosis in adult patients with moyamoya disease.

PubMed

Lee, Jung Keun; Yoon, Byul Hee; Chung, Seung Young; Park, Moon Sun; Kim, Seong Min; Lee, Do Sung

2013-10-01

MR perfusion and single photon emission computerized tomography (SPECT) are well known imaging studies to evaluate hemodynamic change between prior to and following superficial temporal artery (STA)-middle cerebral artery (MCA) anastomosis in moyamoya disease. But their side effects and invasiveness make discomfort to patients. We evaluated the ivy sign on MR fluid attenuated inversion recovery (FLAIR) images in adult patients with moyamoya disease and compared it with result of SPECT and MR perfusion images. We enrolled twelve patients (thirteen cases) who were diagnosed with moyamoya disease and underwent STA-MCA anastomosis at our medical institution during a period ranging from September of 2010 to December of 2012. The presence of the ivy sign on MR FLAIR images was classified as Negative (0), Minimal (1), and Positive (2). Regions were classified into four territories: the anterior cerebral artery (ACA), the anterior MCA, the posterior MCA and the posterior cerebral artery. Ivy signs on preoperative and postoperative MR FLAIR were improved (8 and 4 in the ACA regions, 13 and 4 in the anterior MCA regions and 19 and 9 in the posterior MCA regions). Like this result, the cerebrovascular reserve (CVR) on SPECT was significantly increased in the sum of CVR in same regions after STA-MCA anastomosis. After STA-MCA anastomosis, ivy signs were decreased in the cerebral hemisphere. As compared with conventional diagnostic modalities such as SPECT and MR perfusion images, the ivy sign on MR FLAIR is considered as a useful indicator in detecting brain hemodynamic changes between preoperatively and postoperatively in adult moyamoya patients.

The Usefulness of the Ivy Sign on Fluid-Attenuated Intensity Recovery Images in Improved Brain Hemodynamic Changes after Superficial Temporal Artery-Middle Cerebral Artery Anastomosis in Adult Patients with Moyamoya Disease

PubMed Central

Lee, Jung Keun; Yoon, Byul Hee; Park, Moon Sun; Kim, Seong Min; Lee, Do Sung

2013-01-01

Objective MR perfusion and single photon emission computerized tomography (SPECT) are well known imaging studies to evaluate hemodynamic change between prior to and following superficial temporal artery (STA)-middle cerebral artery (MCA) anastomosis in moyamoya disease. But their side effects and invasiveness make discomfort to patients. We evaluated the ivy sign on MR fluid attenuated inversion recovery (FLAIR) images in adult patients with moyamoya disease and compared it with result of SPECT and MR perfusion images. Methods We enrolled twelve patients (thirteen cases) who were diagnosed with moyamoya disease and underwent STA-MCA anastomosis at our medical institution during a period ranging from September of 2010 to December of 2012. The presence of the ivy sign on MR FLAIR images was classified as Negative (0), Minimal (1), and Positive (2). Regions were classified into four territories: the anterior cerebral artery (ACA), the anterior MCA, the posterior MCA and the posterior cerebral artery. Results Ivy signs on preoperative and postoperative MR FLAIR were improved (8 and 4 in the ACA regions, 13 and 4 in the anterior MCA regions and 19 and 9 in the posterior MCA regions). Like this result, the cerebrovascular reserve (CVR) on SPECT was significantly increased in the sum of CVR in same regions after STA-MCA anastomosis. Conclusion After STA-MCA anastomosis, ivy signs were decreased in the cerebral hemisphere. As compared with conventional diagnostic modalities such as SPECT and MR perfusion images, the ivy sign on MR FLAIR is considered as a useful indicator in detecting brain hemodynamic changes between preoperatively and postoperatively in adult moyamoya patients. PMID:24294453

Indiana Regional Transfer Study: The Student Experience of Transfer Pathways between Ivy Tech Community College and Indiana University

ERIC Educational Resources Information Center

Kadlec, Alison; Gupta, Jyoti

2014-01-01

This report details findings from focus groups with college students across Indiana. All of these students were planning to transfer or had transferred from the state community college system, Ivy Tech, to a school in the Indiana University system. We wanted to find out what these students had to say about their experiences preparing for and…

The Crystal Structure of the Ivy delta4-16:0-ACP Desaturase Reveals Structural Details of the Oxidized Active Site and Potential Determinants of Regioselectivity

DOE Office of Scientific and Technical Information (OSTI.GOV)

Guy,J.; Whittle, E.; Kumaran, D.

2007-01-01

The multifunctional acyl-acyl carrier protein (ACP) desaturase from Hedera helix (English ivy) catalyzes the {Delta}{sup 4} desaturation of 16:0-ACP and the{Delta}{sup 9} desaturation of 18:0-ACP and further desaturates{Delta}{sup 9}-16:1 or {Delta}{sup 9}-18:1 to the corresponding {Delta}{sup 4,9} dienes. The crystal structure of the enzyme has been solved to 1.95{angstrom} resolution, and both the iron-iron distance of 3.2{angstrom} and the presence of a {mu}-oxo bridge reveal this to be the only reported structure of a desaturase in the oxidized FeIII-FeIII form. Significant differences are seen between the oxidized active site and the reduced active site of the Ricinus communis (castor) desaturase;more » His{sup 227} coordination to Fe2 is lost, and the side chain of Glu{sup 224}, which bridges the two iron ions in the reduced structure, does not interact with either iron. Although carboxylate shifts have been observed on oxidation of other diiron proteins, this is the first example of the residue moving beyond the coordination range of both iron ions. Comparison of the ivy and castor structures reveal surface amino acids close to the annulus of the substrate-binding cavity and others lining the lower portion of the cavity that are potential determinants of their distinct substrate specificities. We propose a hypothesis that differences in side chain packing explains the apparent paradox that several residues lining the lower portion of the cavity in the ivy desaturase are bulkier than their equivalents in the castor enzyme despite the necessity for the ivy enzyme to accommodate three more carbons beyond the diiron site.« less

Plant dermatitis. Possible culprits go far beyond poison ivy.

PubMed

Juckett, G

1996-09-01

Given the variety of existing plant species in the environment, it is remarkable that people have adjusted as well as they have to the many plants that can cause uncomfortable skin reactions. With a basic understanding of the types of reaction and the common plants that cause each type, physicians can help patients discover the source of the dermatitis and thus prevent reexposure. In immediate contact dermatitis, welts form rapidly after patients brush against an offending plant, but the urticarial rash is short-lived. In irritant contact dermatitis, the skin is traumatized mechanically (eg, with cactus spines) or chemically (eg, with capsaicin from hot peppers), producing a more persistent skin reaction. Phytophotodermatitis occurs when the skin is exposed to sunlight after contact with an offending plant; reactions are erythema, pruritus, vesiculation, and subsequent hyperpigmentation. Allergic contact dermatitis, typified by the rash of poison ivy, is a cell-mediated immune response that occurs in previously sensitized persons. Erythema, vesiculation, and pruritus, which usually heal without causing pigmentary changes, may last for several weeks.

IVisTMSA: Interactive Visual Tools for Multiple Sequence Alignments.

PubMed

Pervez, Muhammad Tariq; Babar, Masroor Ellahi; Nadeem, Asif; Aslam, Naeem; Naveed, Nasir; Ahmad, Sarfraz; Muhammad, Shah; Qadri, Salman; Shahid, Muhammad; Hussain, Tanveer; Javed, Maryam

2015-01-01

IVisTMSA is a software package of seven graphical tools for multiple sequence alignments. MSApad is an editing and analysis tool. It can load 409% more data than Jalview, STRAP, CINEMA, and Base-by-Base. MSA comparator allows the user to visualize consistent and inconsistent regions of reference and test alignments of more than 21-MB size in less than 12 seconds. MSA comparator is 5,200% efficient and more than 40% efficient as compared to BALiBASE c program and FastSP, respectively. MSA reconstruction tool provides graphical user interfaces for four popular aligners and allows the user to load several sequence files at a time. FASTA generator converts seven formats of alignments of unlimited size into FASTA format in a few seconds. MSA ID calculator calculates identity matrix of more than 11,000 sequences with a sequence length of 2,696 base pairs in less than 100 seconds. Tree and Distance Matrix calculation tools generate phylogenetic tree and distance matrix, respectively, using neighbor joining% identity and BLOSUM 62 matrix.

Study of the intravaginal insert (IVI): acceptability, side effects, and post-coital spermicidal activity.

PubMed

Ahmad, M; Asch, R H

1984-01-01

The authors describe their experience with a group of 49 sexually active, already protected women in order to evaluate the acceptability, side effects and post-coital spermicidal activity of a new vaginal contraceptive. The intravaginal insert (IVI) consists of a polyester resin plug (sponge) containing a 5% solution of nonoxynol-9 bound in a cold formation process, and having a cotton loop attached to the lower end. The results of this study indicate that this new vaginal contraceptive is free of major side effects, is well accepted by users, and has strong spermicidal and mechanical activity. Future clinical testing in order to try its anti-conceptive effectiveness is warranted.

Fabrication of Microfiber Patterns with Ivy Shoot-Like Geometries Using Improved Electrospinning

PubMed Central

Jeong, Young Hun; Lee, Jongwan

2016-01-01

Fibers and fibrous structures are used extensively in various fields due to their many advantages. Microfibers, as well as nanofibers, are considered to be some of the most valuable forms of advanced materials. Accordingly, various methods for fabricating microfibers have been developed. Electrospinning is a useful fabrication method for continuous polymeric nano- and microfibers with attractive merits. However, this technique has limitations in its ability to control the geometry of fibrous structures. Herein, advanced electrospinning with direct-writing functionality was used to fabricate microfiber patterns with ivy shoot-like geometries after experimentally investigating the effects of the process conditions on the fiber formation. The surface properties of the fibers were also modified by introducing nanoscale pores through the use of higher levels of humidity during the fabrication process. PMID:28773390

Fabrication of Microfiber Patterns with Ivy Shoot-Like Geometries Using Improved Electrospinning.

PubMed

Jeong, Young Hun; Lee, Jongwan

2016-04-01

Fibers and fibrous structures are used extensively in various fields due to their many advantages. Microfibers, as well as nanofibers, are considered to be some of the most valuable forms of advanced materials. Accordingly, various methods for fabricating microfibers have been developed. Electrospinning is a useful fabrication method for continuous polymeric nano- and microfibers with attractive merits. However, this technique has limitations in its ability to control the geometry of fibrous structures. Herein, advanced electrospinning with direct-writing functionality was used to fabricate microfiber patterns with ivy shoot-like geometries after experimentally investigating the effects of the process conditions on the fiber formation. The surface properties of the fibers were also modified by introducing nanoscale pores through the use of higher levels of humidity during the fabrication process.

Cost-effective post-exposure prevention of poison ivy dermatitis.

PubMed

Stibich, A S; Yagan, M; Sharma, V; Herndon, B; Montgomery, C

2000-07-01

Poison ivy (toxicodendron) dermatitis is the most common allergic contact dermatitis in the USA. No studies have shown an effect of washing after a short period of time for the prevention of binding of urushiol to the skin. Objective To evaluate the efficacy of three different modes of postcontact prevention using a surfactant (Dial ultra dishwashing soap), an oil-removing compound (Goop), and chemical inactivation (a commercial product Tecnu). A consented, unsponsored, volunteer experimental study on medical students from the University of Missouri School of Medicine, Kansas City. Each subject served as his/her own control, comparing four 2.5-cm exposed squares on the inner aspect of the forearm, three of which were treated and one untreated. Comparisons between the different agents were nonsignificant with P > 0.05. Each treatment, however, was significantly improved over the untreated control. Our study showed 70%, 61.8%, and 56. 4% protection with Tecnu, Goop, and Dial, respectively, when compared to the positive control, or to the possible maximum response, with a cost per ounce (in a local drug and automotive store) of $1.25, $0.07, and $0.07, respectively, for a decrease in protection that is nonsignificant.

"Sorry, but They Don't Want Chinese Americans to Participate": A Case Study of Tracking in an Ivy League Chinese Language Programme

ERIC Educational Resources Information Center

Tian, Ye

2017-01-01

This study examines a Chinese language programme in an Ivy League institution through the lens of Tracking to re-conceptualise the achievement gap between Chinese heritage language learners (CHLLs) and non-heritage language learners. Like most prestigious universities in the U.S., Chinese language learners in this case study are put on one of two…

Pre-release efficacy assessment of the leaf-mining moth Digitivalva delaireae (Lepidoptera: Glyphipterigidae), a potential biological control agent for Cape-ivy, Delairea odorata (Asteraceae), in western North America

USDA-ARS?s Scientific Manuscript database

The leaf-mining moth Digitivalva delaireae Gaedike & Kruger (Lepidoptera: Glyphipterigidae) is a potential biological control agent for the invasive vine Cape-ivy, Delairea odorata Lemaire (Asteraceae), in western North America, where two morphological varieties (stipulate and exstipulate) of Cape-i...

Outdoor Hazards & Preventive Measures: West Nile Virus: A Clinical Commentary for the Camp Health Care Community; Poison Ivy: A Primer for Prevention; Lyme Disease Prevention and Control.

ERIC Educational Resources Information Center

Reynolds, Ellen; Bauer, Holly; Ratner-Connolly, Heidi

2003-01-01

Transmitted by mosquitos, West Nile virus may cause serious illness, but the actual likelihood of infection is low. Prevention, implications, and recommendations for camps are discussed. Poison ivy identification, treatment, and complications are presented; a prevention quiz is included. Signs and symptoms of Lyme disease are described, as are…

Los Angeles congestion reduction demonstration (Metro ExpressLanes) program. National evaluation : transit system data test plan.

DOT National Transportation Integrated Search

1998-09-01

This flyer summarizes the activities and results of a preliminary human factors review for the Intelligent Vehicle Initiative (IVI) Program. As part of the IVI program, the Federal Highway Administration funded a project to investigate the human fact...

An empirical study of the nuclear explosion-induced lightning seen on IVY-MIKE

NASA Astrophysics Data System (ADS)

Colvin, J. D.; Mitchell, C. K.; Greig, J. R.; Murphy, D. P.; Pechacek, R. E.; Raleigh, M.

1987-05-01

We report the results of a unique study of the lightninglike phenomena that were seen to accompany the MIKE shot of operation IVY on October 31 1952. MIKE was a thermonuclear surface burst yielding 10.4 MT, which took place on Enewetak Atoll. During the period of approximately 10 ms after detonation, five discrete luminous channels were seen to start from the ground or sea surface at a distance of approximately 1 km from the burst point and to grow up into the clouds. We have reexamined the original photographic records of IVY-MIKE, obtaining effective brightnesses (optical powers per unit length) for the luminous channels at different altitudes as functions of time. The absolute calibration for the MIKE records was deduced by comparison with the photographic records of other events of that era, laboratory measurements of film sensitivity, and use of atmospheric transmission data taken just prior to the MIKE event. Errors in this analysis lead to an uncertainty of a factor of ˜2 in the brightnesses of the luminous channels. In the laboratory we have used laser-guided electric discharges to create long (100 cm), arclike plasma channels to simulate the observed luminous channels and to allow determination of an empirical relation between the brightness of the channel and the electric current flowing in the channel. These laboratory discharges had peak currents up to 100 kA and periods of ˜2 ms. Spectroscopic analysis showed that the luminous channels consisted primarily of normal air plasma with typical ground-level contaminants. Photographic studies showed that these long-duration discharges are unstable to the m = 1 magnetohydrodynamic (MHD) instability and become severely distorted in less than 1 ms. By direct comparison of the luminous channels seen at MIKE and the laboratory discharges, we deduce: (1) the peak current in the prominent (brightest) channel at MIKE was between 200 and 600 kA. Here the most likely value of the peak current was 250±50 kA, but

Regiospecific attack of nitrogen and sulfur nucleophiles on quinones derived from poison oak/ivy catechols (urushiols) and analogues as models for urushiol-protein conjugate formation.

PubMed

Liberato, D J; Byers, V S; Dennick, R G; Castagnoli, N

1981-01-01

Attempts to characterize potential biologically important covalent interactions between electrophilic quinones derived from catechols present in poison oak/ivy (urushiol) and biomacromolecules have led to the analysis of model reactions involving sulfur and amino nucleophiles with 3-heptadecylbenzoquinone. Characterization of the reaction products indicates that this quinone undergoes regiospecific attack by (S)-N-acetylcysteine at C-6 and by 1-aminopentane at C-5. The red solid obtained with 1-aminopentane proved to be 3-heptadecyl-5-(pentylamino)-1,2-benzoquinone. Analogous aminobenzoquinones were obtained with the quinones derived from the 4- and 6-methyl analogues of 3-pentadecylcatechol. All three adducts absorbed visible light at different wavelengths. When the starting catechols were incubated with human serum albumin almost identical chromophores were formed. These results establish that cathechols responsible for the production of the poison oak/ivy contact dermatitis in humans undergo a sequence of reactions in the presence of human serum albumin that lead to covalent attachment of the catechols to the protein via carbon-nitrogen bonds. Estimations of the extent of this binding indicate that, at least with human serum albumin, the reaction is quantitative.

Assisted reproductive technologies and fertility "tourism": examples from global Dubai and the Ivy League.

PubMed

Inhorn, Marcia C; Shrivastav, Pankaj; Patrizio, Pasquale

2012-01-01

What motivates the global movements of infertile people searching for assisted reproductive technologies (ARTs)? In this article, we attempt to answer this question by exploring infertile patients' practices of so-called "fertility tourism." Based on ethnographic research carried out with nearly 300 infertile travelers in two major ART centers--one in the global hub of the United Arab Emirates and the other at a major East Coast Ivy League university--we examine a diverse set of reasons for reproductive travel. We argue that reproductive "tourism" should be reconceptualized as reproductive "exile" in that infertile couples feel barred from accessing ARTs in their home countries. Listening to reproductive travel stories is key to understanding infertile couples' transnational "quests for conception." Stories of two couples, one from Lebanon and one from Italy, demonstrate the poignancy of these quests and begin to shed light on the complex calculus of factors governing this global movement of reproductive actors.

Protecting Gram-negative bacterial cell envelopes from human lysozyme: Interactions with Ivy inhibitor proteins from Escherichia coli and Pseudomonas aeruginosa.

PubMed

Liu, Zhihong; García-Díaz, Beatriz; Catacchio, Bruno; Chiancone, Emilia; Vogel, Hans J

2015-11-01

Lysozymes play an important role in host defense by degrading peptidoglycan in the cell envelopes of pathogenic bacteria. Several Gram-negative bacteria can evade this mechanism by producing periplasmic proteins that inhibit the enzymatic activity of lysozyme. The Escherichia coli inhibitor of vertebrate lysozyme, Ivyc and its Pseudomonas aeruginosa homolog, Ivyp1 have been shown to be potent inhibitors of hen egg white lysozyme (HEWL). Since human lysozyme (HL) plays an important role in the innate immune response, we have examined the binding of HL to Ivyc and Ivyp1. Our results show that Ivyp1 is a weaker inhibitor of HL than Ivyc even though they inhibit HEWL with similar potency. Calorimetry experiments confirm that Ivyp1 interacts more weakly with HL than HEWL. Analytical ultracentrifugation studies revealed that Ivyp1 in solution is a monomer and forms a 30kDa heterodimer with both HL and HEWL, while Ivyc is a homodimer that forms a tetramer with both enzymes. The interaction of Ivyp1 with HL was further characterized by NMR chemical shift perturbation experiments. In addition to the characteristic His-containing Ivy inhibitory loop that binds into the active site of lysozyme, an extended loop (P2) between the final two beta-strands also participates in forming protein-protein interactions. The P2 loop is not conserved in Ivyc and it constitutes a flexible region in Ivyp1 that becomes more rigid in the complex with HL. We conclude that differences in the electrostatic interactions at the binding interface between Ivy inhibitors and distinct lysozymes determine the strength of this interaction. This article is part of a Special Issue entitled: Bacterial Resistance to Antimicrobial Peptides. Copyright © 2015 Elsevier B.V. All rights reserved.

Keratinocyte interleukin-10 expression is upregulated in tape-stripped skin, poison ivy dermatitis, and Sezary syndrome, but not in psoriatic plaques.

PubMed

Nickoloff, B J; Fivenson, D P; Kunkel, S L; Strieter, R M; Turka, L A

1994-10-01

Despite the highly diverse reaction patterns of benign and malignant skin diseases involving T lymphocytes, polymerase chain reaction analysis of cytokine mRNAs present in biopsy samples has revealed that many cutaneous responses can be categorized into essentially two discrete groups. One group exemplified by psoriasis is characterized by consistently detectable mRNAs for IL-2, IFN-gamma, and TNF-alpha, but not IL-4, IL-5, IL-10, thereby closely resembling the murine Th1-type cell-mediated response. The second group exemplified by tape-stripped skin, poison ivy dermatitis, and Sezary syndrome contains predominantly IL-4, IL-5, and IL-10 mRNAs resembling the Th2-type cytokine profile. Because of the growing interest in the immunoregulatory role of IL-10, which can suppress IFN-gamma production and inhibit cell-mediated reactions, we produced a rabbit antiserum that was used to immunohistochemically localize IL-10 in a total of 27 biopsies. The results revealed that in Th2-type skin diseases, IL-10 was predominantly identified throughout all levels of epidermis in the cytoplasm of keratinocytes (KCs), with accentuation of their membranes in upper level cells. In Sezary syndrome, T cells were also immunoreactive for IL-10, which was confirmed using the HUT 78 T cell line derived from a Sezary syndrome patient. While normal skin was devoid of IL-10 expression, KCs began expressing it as early as 6 hr following tape stripping or application of poison ivy antigen and became strongly and diffusely positive by 18-24 hr. In contrast, psoriatic plaques contained no IL-10 immunoreactivity in either the parakeratotic scale or the epidermal KCs. These results confirm the earlier IL-10 mRNA analysis using whole skin samples and immunolocalize IL-10 to epidermal KCs in the Th2 diseases.

[Selected adjuvants as carriers of a dry extract of common ivy (Hedera helix L.)].

PubMed

Marczyński, Zbigniew; Zgoda, Marian Mikołaj; Bodek, Kazimiera Henryka

2011-01-01

The usefulness was tested of selected adjuvants: Vivapur 112, Carmellose calcium, Calcium carbonate CA 740, Calcium carbonate CA 800, Hypromellose as carriers of a dry extract of common ivy (Hedera helix L.) leaves in the process of direct tableting. The quality of the produced tablets was determined by examining their appearance, diameter, thickness, mass resistance to abrasion, crushing and disintegration time. Furthermore, the rate of release of biologically active components from the produced drug form to acceptor fluid was tested in accordance with the requirements of Polish Pharmacopoeia VII (PPVII). An attempt was made to estimate the effect of the used adjuvants on the course of this process. The applied adjuvants and acceptor fluid osmolarity decide significantly about the pharmaceutical availability of the therapeutic agents contained in the extract. The obtained model tablets are characterized by controlled release of biologically active substances, in majority of batches they fulfil the requirements as regards physicochemical properties. The formulation composition of the first batch (Extr. Hederae helices e fol.spir. sicc., Vivapur 112, Carmellose calcium, Sodium Stearyl Fumarate) appeared to be the most effective. The worked out method is optimal and provides technological reproducibility and high durability of the drug form.

Reconnaissance Report for Section 205 Flood Control: Illinois and Michigan Canal, La Salle and Grundy Counties, Illinois

DTIC Science & Technology

1989-09-01

cattail, rice cutgrass, jewelweed , poison ivy and many other species. This corridor provides habitat for deer, squirrel, raccoon, fox, skunk, rabbit, wood...typical bottomland species like sycamore, hackberry, cottonwood, silver maple, boxelder and green ash. Understory vegetation includes poison ivy , nettles... jewelweed , greenbrier, Solomon’s seal, and many other woody and herbaceous plants. The remnant of canal included in this project has little or no

Effects of nozzle type and spray angle on spray deposition in ivy pot plants.

PubMed

Foqué, Dieter; Nuyttens, David

2011-02-01

Fewer plant protection products are now authorised for use in ornamental growings. Frequent spraying with the same product or a suboptimal technique can lead to resistance in pests and diseases. Better application techniques could improve the sustainable use of the plant protection products still available. Spray boom systems--instead of the still predominantly used spray guns--might improve crop protection management in greenhouses considerably. The effect of nozzle type, spray pressure and spray angle on spray deposition and coverage in ivy pot plants was studied, with a focus on crop penetration and spraying the bottom side of the leaves in this dense crop. The experiments showed a significant and important effect of collector position on deposition and coverage in the plant. Although spray deposition and coverage on the bottom side of the leaves are generally low, they could be improved 3.0-4.9-fold using the appropriate application technique. When using a spray boom in a dense crop, the nozzle choice, spray pressure and spray angle should be well considered. The hollow-cone, the air-inclusion flat-fan and the standard flat-fan nozzle with an inclined spray angle performed best because of the effect of swirling droplets, droplets with a high momentum and droplet direction respectively. Copyright © 2010 Society of Chemical Industry.

Idea Project Final Report, Passive Optical Lane Position Monitor

DOT National Transportation Integrated Search

1996-01-01

INTELLIGENT VEHICLE INITIATIVE OR IVI : THIS INVESTIGATION WAS COMPLETED AS PART OF THE ITS-IDEA PROGRAM, WHICH IS ONE OF THREE IDEA PROGRAMS MANAGED BY THE TRANSPORTATION RESEARCH BOARD (TRB) TO FOSTER INNOVATIONS IN SURFACE TRANSPORTATION. IT FOCUS...

The Tn Antigen-Specific Lectin from Ground Ivy Is an Insecticidal Protein with an Unusual Physiology1

PubMed Central

Wang, Weifang; Hause, Bettina; Peumans, Willy J.; Smagghe, Guy; Mackie, Anne; Fraser, Robin; Van Damme, Els J.M.

2003-01-01

Leaves of ground ivy (Glechoma hederacea) contain a lectin (called Gleheda) that is structurally and evolutionary related to the classical legume lectins. Screening of a population of wild plants revealed that Gleheda accounts for more than one-third of the total leaf protein in some clones, whereas it cannot be detected in other clones growing in the same environment. Gleheda is predominantly expressed in the leaves where it accumulates during early leaf maturation. The lectin is not uniformly distributed over the leaves but exhibits a unique localization pattern characterized by an almost exclusive confinement to a single layer of palisade parenchyma cells. Insect feeding trials demonstrated that Gleheda is a potent insecticidal protein for larvae of the Colorado potato beetle (Leptinotarsa decemlineata). Because Gleheda is not cytotoxic, it is suggested that the insecticidal activity is linked to the carbohydrate-binding specificity of the lectin, which as could be demonstrated by agglutination assays with different types of polyagglutinable human erythrocytes is specifically directed against the Tn antigen structure (N-acetylgalactosamine O-linked to serine or threonine residues of proteins). PMID:12857814

Urushiol (poison ivy)-triggered suppressor T cell clone generated from peripheral blood.

PubMed Central

Kalish, R S; Morimoto, C

1988-01-01

Allergic contact dermatitis to Toxicodendron radicans (poison ivy) is mediated by the hapten urushiol. An urushiol-specific, interleukin 2 (IL-2)-dependent T cell clone (RLB9-7) was generated from the peripheral blood of a patient with a history of allergic contact dermatitis to T. radicans. This clone proliferated specifically to both leaf extract and pure urushiol. Although the clone had the phenotype CD3+CD4+CD8+, proliferation to antigen was blocked by anti-CD8 and anti-HLA-A, B, C, but not by anti-CD4, suggesting that CD4 was not functionally associated with the T cell receptor. Furthermore, studies with antigen-presenting cells from MHC-typed donors indicated that the clone was MHC class 1 restricted. RLB9-7 was WT31 positive, indicating it bears the alpha beta T cell receptor. The clone lacked significant natural killer cell activity and produced only low levels of IL-2 or gamma-interferon upon antigen stimulation. Addition of RLB9-7 to autologous peripheral blood mononuclear cells in the presence of urushiol inhibited the pokeweed mitogen-driven IgG synthesis. This suppression was resistant to irradiation (2,000 rad) and was not seen when RLB9-7 was added to allogeneic cells, even in the presence of irradiated autologous antigen-presenting cells, suggesting that suppression was MHC restricted and not mediated by nonspecific soluble factors. However, RLB9-7 cells in the presence of urushiol inhibited the synthesis of tetanus toxoid-specific IgG by autologous lymphocytes, indicating that the suppression, although triggered specifically by urushiol, was nonspecific. PMID:2458387

[Severe contact-allergy dermatitis due to poison ivy--a plant that is rarely encountered in The Netherlands; a family history].

PubMed

Leclercq, R M F M

2005-07-23

In successive years, three members of the same family (a man and woman aged 46 years and their son, aged 20) constantly developed severe pruritic, erythematous, vesicular and bullous dermatitis in the spring and summer after working in the garden. Although the findings were consistent with a photophytotoxic dermatitis, the causative plant remained unclear. Oral therapy with high doses ofprednisolone was necessary. When the man travelled to the USA and visited a doctor there, he recognised the symptoms as those of contact dermatitis caused by poison ivy (Toxicodendron radicans), a plant that is found sporadically in the wild state in Europe. Their grandparents had brought the plant back from a trip to the USA and planted it in the garden because of the beautiful fall colours. The family identified the plant via a search on Internet and eliminated it from the garden completely. Since then, the family has no longer suffered from contact-allergy dermatitis.

Status of biological control projects on terrestrial invasive alien weeds in California

USDA-ARS?s Scientific Manuscript database

In cooperation with foreign scientists, we are currently developing new classical biological control agents for five species of invasive alien terrestrial weeds. Cape-Ivy. A gall-forming fly, Parafreutreta regalis, and a stem-boring moth, Digitivalva delaireae, have been favorably reviewed by TAG...

Processing of urushiol (poison ivy) hapten by both endogenous and exogenous pathways for presentation to T cells in vitro.

PubMed

Kalish, R S; Wood, J A; LaPorte, A

1994-05-01

The antigen processing requirements for urushiol, the immunogen of poison ivy (Toxicodendron radicans), were tested by presentation of urushiol to cultured human urushiol-responsive T cells. Urushiol was added to antigen-presenting cells (APC) either before or after fixation with paraformaldehyde. Three distinct routes of antigen processing were detected. CD8+ and CD4+ T cells, which were dependent upon processing, proliferated if urushiol was added to APC before fixation, but did not proliferate when urushiol was added to APC after fixation. Processing of urushiol for presentation to CD8+ T cells was inhibited by azide, monensin, and brefeldin A. This suggests that urushiol was processed by the endogenous pathway. In contrast, presentation of urushiol to CD4+ T cells was inhibited by monensin but not by brefeldin A. This was compatible with antigen processing by the endosomal (exogenous) pathway. Finally, certain CD8+ T cells recognized urushiol in the absence of processing. These cells proliferated in response to APC incubated with urushiol after fixation. Classification of contact allergens by antigen processing pathway may predict the relative roles of CD4+ and CD8+ cells in the immunopathogensis of allergic contact dermatitis.

Processing of urushiol (poison ivy) hapten by both endogenous and exogenous pathways for presentation to T cells in vitro.

PubMed Central

Kalish, R S; Wood, J A; LaPorte, A

1994-01-01

The antigen processing requirements for urushiol, the immunogen of poison ivy (Toxicodendron radicans), were tested by presentation of urushiol to cultured human urushiol-responsive T cells. Urushiol was added to antigen-presenting cells (APC) either before or after fixation with paraformaldehyde. Three distinct routes of antigen processing were detected. CD8+ and CD4+ T cells, which were dependent upon processing, proliferated if urushiol was added to APC before fixation, but did not proliferate when urushiol was added to APC after fixation. Processing of urushiol for presentation to CD8+ T cells was inhibited by azide, monensin, and brefeldin A. This suggests that urushiol was processed by the endogenous pathway. In contrast, presentation of urushiol to CD4+ T cells was inhibited by monensin but not by brefeldin A. This was compatible with antigen processing by the endosomal (exogenous) pathway. Finally, certain CD8+ T cells recognized urushiol in the absence of processing. These cells proliferated in response to APC incubated with urushiol after fixation. Classification of contact allergens by antigen processing pathway may predict the relative roles of CD4+ and CD8+ cells in the immunopathogensis of allergic contact dermatitis. Images PMID:7910172

Isolation of a phytotoxic isocoumarin from Diaporthe eres-infected Hedera helix (English ivy) and synthesis of its phytotoxic analogs.

PubMed

Meepagala, Kumudini M; Briscoe, William E; Techen, Natascha; Johnson, Robert D; Clausen, Brandon M; Duke, Stephen O

2018-01-01

The fungus Diaporthe eres was isolated from a fungal pathogen-infected leaf of Hedera helix (English ivy) exhibiting necrosis. It is hypothesized that the causative fungus produces phytotoxins as evidenced by necrotic lesions on the leaves. The fungus was isolated and grown in Czapek Dox broth culture medium and potato dextrose broth culture medium and identified as Diaporthe eres. The ethyl acetate extracts of the culture broths were phytotoxic to lettuce (Lactuca sativa) and bentgrass (Agrostis stolonifera). 3,4-Dihydro-8-hydroxy-3,5-dimethylisocoumarin (1) and tyrosol (2) were isolated and identified as the phytotoxic constituents. Six analogs of 3,4-dihydro-isocoumarin were synthesized and shown to be phytotoxic. The synthesized 3,4-dihydro-8-hydroxy-3,7-dimethylisocoumarin and 3,4-dihydro-8-hydroxy-3,3,7-trimethylisocoumarin were two- to three-fold more phytotoxic than the naturally occurring 1 in a Lemna paucicostata growth bioassay. Synthesis and herbicidal activities of the several new analogs of 1 are reported for the first time. These promising molecules should be used as templates for synthesis and testing of more analogs. © 2017 Society of Chemical Industry. © 2017 Society of Chemical Industry.

Intelligent transportation systems publications

DOT National Transportation Integrated Search

1996-01-01

This compendium focuses on projects that represent activities which have supported the evolution of the Intelligent Vehicle Initiative (IVI) and partly or totally funded by the Federal Highway Administration (FHWA) or the National Highway Traffic Saf...

Induction of hapten-specific tolerance of human CD8+ urushiol (poison ivy)-reactive T lymphocytes.

PubMed

Kalish, R S; Wood, J A

1997-03-01

The interaction of CD28 with B7 molecules (CD80 or CD86) is an essential second signal for both the activation of CD4+ T cells through the T-cell receptor and the prevention of anergy. We studied the requirement of hapten-specific human CD8+ cells for CD28 co-stimulation in recognition of hapten, and anergy induction. Urushiol, the immunogenic hapten of poison ivy (Toxicodendron radicans), elicits a predominantly CD8+ T-cell response. Autologous PBMC were pre-incubated with urushiol prior to fixation by paraformaldehyde. Fixed antigen-presenting cells were unable to present urushiol to human CD8+ urushiol-specific T cells. Addition of anti-CD28, however, overcame this antigen-presenting defect, enabling CD8+ cells to proliferate. Fixation of antigen-presenting cells prevents upregulation of B7, and addition of anti-CD28 substitutes for this signal. Proliferation of CD8+ T cells in response to urushiol was blocked by CTLA4Ig, a recombinant fusion protein that blocks CD28/B7 interactions. Preincubation of urushiol-specific CD8+ cells with fixed PBMC + urushiol for 7 d induced anergy. Anergic CD8+ cells were viable and able to proliferate in response to IL-2, but not in response to urushiol. Induction of anergy required the presence of urushiol, and pre-incubation with irradiated PBMC + urushiol did not have this effect. It is proposed that anergy was induced by presentation of urushiol by fixed PBMC, in the absence of adequate co-stimulation signals. Induction of anergy by blocking of co-stimulation could potentially induce clinical hyposensitization to haptens.

Down-regulation of poison ivy/oak-induced contact sensitivity by treatment with a class II MHC binding peptide:hapten conjugate.

PubMed

Gelber, C; Gemmell, L; McAteer, D; Homola, M; Swain, P; Liu, A; Wilson, K J; Gefter, M

1997-03-01

Immune regulation of contact sensitivity to the poison ivy/oak catechol was studied at the level of class II MHC-restricted T cell recognition of hapten:peptide conjugates. In this study we have shown that 1) T cells from C3H/HeN (H-2k) mice, immunized with a synthetic I-Ak binding peptide coupled to 3-pentadecyl-catechol (PDC; a representative catechol in urushiol), recognized peptides derived from syngeneic cells linked to the same catechol; 2) T cells from draining lymph nodes of C3H/HeN mice skin-painted with PDC proliferated in response to a peptide carrier:PDC conjugate only when it was linked at the 7th, but not the 4th or the 10th, position on the peptide carrier; and 3) tolerization studies confirmed down-regulation of PDC-induced delayed-type hypersensitivity following treatment with a single I-Ak binding peptide carrying PDC covalently bound to a lysine residue at the middle (7th) TCR contact position. Tolerization with peptide:PDC conjugate resulted in abrogation of hapten-specific T cell proliferative responses that correlated with diminished IL-2 secretion. On the basis of these data we propose that it may be sufficient to couple the hapten at a single, well-chosen position on a carrier peptide to target a relevant population of T cells involved in contact sensitivity.

Kinesthetic Imagery Provides Additive Benefits to Internal Visual Imagery on Slalom Task Performance.

PubMed

Callow, Nichola; Jiang, Dan; Roberts, Ross; Edwards, Martin G

2017-02-01

Recent brain imaging research demonstrates that the use of internal visual imagery (IVI) or kinesthetic imagery (KIN) activates common and distinct brain areas. In this paper, we argue that combining the imagery modalities (IVI and KIN) will lead to a greater cognitive representation (with more brain areas activated), and this will cause a greater slalom-based motor performance compared with using IVI alone. To examine this assertion, we randomly allocated 56 participants to one of the three groups: IVI, IVI and KIN, or a math control group. Participants performed a slalom-based driving task in a driving simulator, with average lap time used as a measure of performance. Results revealed that the IVI and KIN group achieved significantly quicker lap times than the IVI and the control groups. The discussion includes a theoretical advancement on why the combination of imagery modalities might facilitate performance, with links made to the cognitive neuroscience literature and applied practice.

A comparative study to determine the optimal intravitreal injection angle to the eye: A computational fluid-structure interaction model.

PubMed

Karimi, Alireza; Razaghi, Reza; Biglari, Hasan; Sabbaghi, Hamideh; Sera, Toshihiro; Kudo, Susumu

2018-04-20

This study was aimed at investigating the role of IVI angle on the induced stresses and deformations among the components of the eye. Thereafter, the most optimal angle of IVI to minimize the complications of post IVI at the injection site on a basis of the computed stresses via a Fluid-Structure Interaction (FSI) computational model was proposed. IntraVitreal Injection (IVI) is broadly employed as a principal treatment of vascular vitro-retinal diseases. So far, there have been reports regarding the complications of post IVI and determine them as severe uveitis, tractional retinal detachment, IntraOcular Pressure (IOP) elevation as well as ocular haemorrhage. However, there is a lack of knowledge on how to reduce the subsequent ocular tissue damage and patient symptoms in the injection site. Seven different IVI angles were simulated, including 0∘, 15∘, 30∘, 45∘, 60∘, 75∘, and 90∘, through the Finite Element (FE) code; and the term, 'post IVI complication' or 'injury', in the results was interpreted as the level of maximal principal stress in the eye components. The results revealed the lowest amount of stresses at the angle of 45∘ in respect to the horizontal line (acute to the surface of the sclera) for the lens, iris, vitreous body, aqueous body, ciliary body, sclera, retina, and choroid. The cornea illustrated the same amount of stress at the angles of 45∘, 60∘, 75∘, and 90∘ with the highest one at the IVI angle of 30∘. The lowest and the highest stresses among the eye components regardless of IVI angle were observed in the choroid and retina/sclera, respectively, which imply the importance of the IVI angle on the stresses of these eye components. The findings of the contemporary research revealed that the IVI angle of 45∘ would trigger less post IVI complications and, as a result, a more effective surgery outcome compared to the other angles, i.e., 0∘, 15∘, 30∘, 60∘, 75∘, and 90∘.

2003 status report on transit intelligent vehicle initiative studies

DOT National Transportation Integrated Search

2003-06-01

This 2003 Status Report provides an overview and updates on studies in the transit Intelligent Vehicle Initiative (IVI) area. IVI emphasizes the significant and continuing role of drivers in roadway safety. IVI is aimed at accelerating the developmen...

Performance improvements from imagery: evidence that internal visual imagery is superior to external visual imagery for slalom performance

PubMed Central

Callow, Nichola; Roberts, Ross; Hardy, Lew; Jiang, Dan; Edwards, Martin Gareth

2013-01-01

We report three experiments investigating the hypothesis that use of internal visual imagery (IVI) would be superior to external visual imagery (EVI) for the performance of different slalom-based motor tasks. In Experiment 1, three groups of participants (IVI, EVI, and a control group) performed a driving-simulation slalom task. The IVI group achieved significantly quicker lap times than EVI and the control group. In Experiment 2, participants performed a downhill running slalom task under both IVI and EVI conditions. Performance was again quickest in the IVI compared to EVI condition, with no differences in accuracy. Experiment 3 used the same group design as Experiment 1, but with participants performing a downhill ski-slalom task. Results revealed the IVI group to be significantly more accurate than the control group, with no significant differences in time taken to complete the task. These results support the beneficial effects of IVI for slalom-based tasks, and significantly advances our knowledge related to the differential effects of visual imagery perspectives on motor performance. PMID:24155710

Report on Phase 2 Archaeological Testing at 21 AK 11, Big Sandy Lake, Aitkin County, Minnesota (June 10-11 and August 1-5 and 20-21, 1985)

DTIC Science & Technology

1987-10-05

Hazelnut Hazelnut Poison ivy Round-leaved Black currant Hazelnut dogwood’ Juneberry Round-leaved Downy arrowwood Chokecherry dogwood Poison ivy...Poison ivy Chokecherry Wild grape Sandbar Willow Black raspberry Bush honeysuckle Smooth wild rose Virginia creeper Bush honeysuckle Juneberry

Echolalic responses by a child with autism to four experimental conditions of sociolinguistic input.

PubMed

Violette, J; Swisher, L

1992-02-01

Studies of the immediate verbal imitations (IVIs) of subjects with echolalia report that features of linguistic or social input alone affect the number of IVIs elicited. This experimental study of a child with echolalia and autism controlled each of these variables while introducing a systematic change in the other. The subject produced more (p less than .05) IVIs in response to unknown lexical words presented with a high degree of directiveness (Condition D) than in response to three other conditions of stimulus presentation (e.g., unknown lexical words, minimally directive style.) Thus, an interaction between the effects of linguistic and social input was demonstrated. IVIs were produced across all conditions, primarily during first presentations of lexical stimuli. Only the IVIs elicited by first presentations of the lexical stimuli during Condition D differed significantly (p less than .05) from the number of IVIs elicited by first presentations of lexical stimuli in other conditions. These findings viewed together suggest that the occurrence of IVIs was related, at least for this child, to an uncertain or informative event and that this response was significantly greater when the lexical stimuli were unknown and presented in a highly directive style.

Moving Minds

ERIC Educational Resources Information Center

Parker, Terry; Hiett, Sandra; Marley, Donna

2006-01-01

This paper explores and examines a case study based at Ivy Bank Business and Enterprise College, The Imperial War Museum North, and Liverpool John Moores University. This collaboration took place from November 2004 until February 2005 culminating in an exhibition of children's artwork as part of the "Moving Minds" project at the IWM North. This…

Statement of Facts for 1983 City-Wide Mock Trial Competitions. The Case of Vickers v. Hearst. No. MT-84.

ERIC Educational Resources Information Center

National Inst. for Citizen Education in the Law, Washington, DC.

Prepared by the District of Columbia Street Law Project for its annual city-wide mock trial competition, this instructional handout provides material for a civil case over an automobile accident. After drinking heavily at a party hosted by Sandy Hearst, Dana Ivy ran a stop sign and struck the car of Terry Vickers, causing him to sustain a broken…

Scientific Literacy: A Non-Traditional Approach to Science for Students Outside of Technical Fields.

ERIC Educational Resources Information Center

Shotwell, R. Allen

Although the goal of science courses for non-majors should be to increase the scientific literacy of students, many such courses become watered down versions of courses in the major and do not provide enough depth to make science meaningful to students. At the Wabash Valley Region campus of Ivy Tech State College, in Indiana, a project was…

Current status of establishing a venous line in CPA patients by Emergency Life-Saving Technicians in the prehospital setting in Japan and a proposal for intraosseous infusion.

PubMed

Isayama, Kenji; Nakatani, Toshio; Tsuda, Masanobu; Hirakawa, Akihiko

2012-01-09

It is important to have a venous line in cardiopulmonary arrest (CPA) patients as an emergency treatment measure in prehospital settings, but establishment of a peripheral venous line is difficult in such patients. This study aimed to investigate the current status of intravenous infusion (IVI) in CPA patients by Emergency Life-Saving Technicians (ELSTs) in Japan. We also considered alternative measures in case IVI was difficult or impossible. We investigated a nationwide database between 1 January 2005 and 31 December 2008. From a total of 431,968 CPA cases, we calculated the IVI success rate and related parameters.The Bone Injection Gun (BIG) and simulator legs (adult, pediatric, and infant) were used by 100 ELSTs selected for the study to measure the time required and the success rate for intraosseous infusion (IOI). The number of CPA patients, IVI, adrenaline administration, and the IVI success rate in adult CPA patients increased every year. However, the IVI success rate in pediatric CPA patients did not increase. Although adrenaline administration elevated the ROSC rate, there was no improvement in the 1-month survival rate. The time required for IOI with BIG was not different among the leg models. The success rates of IOI with BIG were 93%, 94%, and 84% (p < 0.05 vs. adult and pediatric) in adult, pediatric, and infant models, respectively. The rate of success of IVI in adult CPA patients has been increased yearly in Japan. However, as establishing a peripheral venous line in pediatric patients (1-7 years old) by ELSTs is extremely difficult in prehospital settings, there was no increase in the IVI success rate in such patients. As the study findings indicated IOI with BIG was easy and rapid, it may be necessary to consider IOI with BIG as an alternative option in case IVI is difficult or impossible in adult and pediatric patients.

Revised generic placement of Brachypelma embrithes (Chamberlin & Ivie, 1936) and Brachypelma angustum Valerio, 1980, with definition of the taxonomic features for identification of female Sericopelma Ausserer, 1875 (Araneae, Theraphosidae)

PubMed Central

Gabriel, Ray; Longhorn, Stuart J.

2015-01-01

Abstract The tarantula genus Sericopelma was originally defined based on male specimens, most notably lacking tibial spurs on leg I. Early female specimens were unrecognised as Sericopelma, and typically placed in Eurypelma – a dumping ground for problem specimens. The first females were only later recognised, but authors failed to adequately define female Sericopelma. Here, the holotypes of the southern-most alleged Brachypelma species, Brachypelma embrithes (Chamberlin & Ivie, 1936) and Brachypelma angustum Valerio, 1980 were examined, and finding both to possess defining characteristics of Sericopelma were transferred. The taxonomic attributes to define Sericopelma relative to Brachypelma and select other Neotropical genera are discussed, especially for females. As important diagnostic characters for Sericopelma, the single (unilobar) spermathecae swollen at the apex forming a P-shaped cross-section, metatarsus IV with trace scopula, femur IV with a dense retrolateral pad of plumose hair, plus other attributes. Some past confusion in these characters are clarified and Sericopelma relative to Brachypelma and Megaphobema mesomelas are discussed. Finally recommendations are given about these taxonomic changes for CITES regulations. PMID:26487826

Final Programmatic Environmental Impact Statement, Lake Darling Flood Control Project, Souris River, North Dakota and Final Feature Environmental Impact Statement, Velva Flood Control, Velva, North Dakota.

DTIC Science & Technology

1983-11-01

plant species found in the floodplain forest are elm, green ash, box elder, bur oak, willow, cottonwood, hawthorn, chokecherry , dogwood, wolfberry, and...understory of grape, sorrel, meadow rue, poison ivy, rose, and cocklebur. These species plus chokecherry and black currant grow in some of the upland

Draft Programmatic Environmental Impact Statement, Lake Darling Flood Control Project, Souris River, North Dakota and Draft Feature Environmental Impact Statement Velva Flood Control, Velva, North Dakota.

DTIC Science & Technology

1982-10-01

oak, willow, cottonwood, hawthorn, chokecherry , dogwood, wolfberry, and wild rose. 9 - . -t 4.17 Wetlands - The three general categories of wetlands of...an understory of grape, sorrel, meadow rue, poison ivy, rose, cocklebur, and chokecherry and black currant in some of the upland areas. Evidence of

Talking to your car can drive you to distraction.

PubMed

Strayer, David L; Cooper, Joel M; Turrill, Jonna; Coleman, James R; Hopman, Rachel J

2016-01-01

This research examined the impact of in-vehicle information system (IVIS) interactions on the driver's cognitive workload; 257 subjects participated in a weeklong evaluation of the IVIS interaction in one of ten different model-year 2015 automobiles. After an initial assessment of the cognitive workload associated with using the IVIS, participants took the vehicle home for 5 days and practiced using the system. At the end of the 5 days of practice, participants returned and the workload of these IVIS interactions was reassessed. The cognitive workload was found to be moderate to high, averaging 3.34 on a 5-point scale and ranged from 2.37 to 4.57. The workload was associated with the intuitiveness and complexity of the system and the time it took participants to complete the interaction. The workload experienced by older drivers was significantly greater than that experienced by younger drivers performing the same operations. Practice did not eliminate the interference from IVIS interactions. In fact, IVIS interactions that were difficult on the first day were still relatively difficult to perform after a week of practice. Finally, there were long-lasting residual costs after the IVIS interactions had terminated. The higher levels of workload should serve as a caution that these voice-based interactions can be cognitively demanding and ought not to be used indiscriminately while operating a motor vehicle.

Second-year visual acuity outcomes of nAMD patients treated with aflibercept: data analysis from the UK Aflibercept Users Group.

PubMed

Almuhtaseb, H; Johnston, R L; Talks, J S; Lotery, A J

2017-11-01

PurposeTo audit the visual acuity (VA) outcomes achieved at the end of year two in 17 UK centres, which followed the year 1 VIEW protocol in year 1, but a variable approach in year 2 for aflibercept for neovascular macular degeneration (nAMD).Patients and methodsRetrospective data analysis, from an electronic medical record, of a consecutive series of treatment-naive nAMD patients who received aflibercept for 2 consecutive years, having followed the VIEW protocol in year one, defined as eyes having received 7 or 8 injections from baseline.ResultsThe mean number of intravitreal injections (IVI)s during year 2 was 3.7 in 1180 eyes (1083 patients). The mean baseline VA of the whole cohort was 56.3 ETDRS letters, improving to 61.3 at 1 year (+5) and 59.1 (+2.8) at the end of year 2. The mean VA letter score at the end of year 2, stratified by number of IVIs into three groups was as follows: group A, 57.3 (gain of +1.7) (44% of eyes (IVIs)); group B, 59.8 (+3.8) (34% of eyes (4-5 IVIs)); group C, 61.7 (+3.7) (22% of eyes (>/=6 IVIs)). Even though there were VA gains in the three groups over the 2-years, there was a drop in VA in year one to two. Eyes that received >/=6 IVIs (group C) had a smaller reduction of VA during year 2 than those which received IVIs (group A) (P=0.0014).ConclusionsProviding a higher number of injections after a Q8 regime in year 1 results in higher VA gains in year 2 of treatment.

Improving the antiprotozoal effect of saponins in the rumen by combination with glycosidase inhibiting iminosugars or by modification of their chemical structure.

PubMed

Ramos-Morales, Eva; de la Fuente, Gabriel; Nash, Robert J; Braganca, Radek; Duval, Stephane; Bouillon, Marc E; Lahmann, Martina; Newbold, C Jamie

2017-01-01

The antiprotozoal effect of saponins is transitory, as when saponins are deglycosylated to sapogenins by rumen microorganisms they become inactive. We hypothesised that the combination of saponins with glycosidase-inhibiting iminosugars might potentially increase the effectiveness of saponins over time by preventing their deglycosylation in the rumen. Alternatively, modifying the structure of the saponins by substituting the sugar moiety with other small polar residues might maintain their activity as the sugar substitute would not be enzymatically cleaved. The aim of this in vitro study was to evaluate the acute antiprotozoal effect and the stability of this effect over a 24 h incubation period using ivy saponins, a stevia extract rich in iminosugars, ivy saponins with stevia extract, and a chemically modified ivy saponin, hederagenin bis-succinate (HBS). The effects on fermentation parameters and rumen bacterial communities were also studied. Ivy saponins with stevia and HBS had a greater antiprotozoal effect than ivy saponins, and this effect was maintained after 24 h of incubation (P<0.001). The combination of ivy and stevia extracts was more effective in shifting the fermentation pattern towards higher propionate (+39%) and lower butyrate (-32%) and lower ammonia concentration (-64%) than the extracts incubated separately. HBS caused a decrease in butyrate (-45%) and an increase in propionate (+43%) molar proportions. However, the decrease in ammonia concentration (-42%) observed in the presence of HBS was less than that caused by ivy saponins, either alone or with stevia. Whereas HBS and stevia impacted on bacterial population in terms of community structure, only HBS had an effect in terms of biodiversity (P<0.05). It was concluded that ivy saponins with stevia and the modified saponin HBS had a strong antiprotozoal effect, although they differed in their effects on fermentation parameters and bacteria communities. Ivy saponins combined with an iminosugar

Improving the antiprotozoal effect of saponins in the rumen by combination with glycosidase inhibiting iminosugars or by modification of their chemical structure

PubMed Central

de la Fuente, Gabriel; Nash, Robert J.; Braganca, Radek; Duval, Stephane; Bouillon, Marc E.; Lahmann, Martina; Newbold, C. Jamie

2017-01-01

The antiprotozoal effect of saponins is transitory, as when saponins are deglycosylated to sapogenins by rumen microorganisms they become inactive. We hypothesised that the combination of saponins with glycosidase-inhibiting iminosugars might potentially increase the effectiveness of saponins over time by preventing their deglycosylation in the rumen. Alternatively, modifying the structure of the saponins by substituting the sugar moiety with other small polar residues might maintain their activity as the sugar substitute would not be enzymatically cleaved. The aim of this in vitro study was to evaluate the acute antiprotozoal effect and the stability of this effect over a 24 h incubation period using ivy saponins, a stevia extract rich in iminosugars, ivy saponins with stevia extract, and a chemically modified ivy saponin, hederagenin bis-succinate (HBS). The effects on fermentation parameters and rumen bacterial communities were also studied. Ivy saponins with stevia and HBS had a greater antiprotozoal effect than ivy saponins, and this effect was maintained after 24 h of incubation (P<0.001). The combination of ivy and stevia extracts was more effective in shifting the fermentation pattern towards higher propionate (+39%) and lower butyrate (-32%) and lower ammonia concentration (-64%) than the extracts incubated separately. HBS caused a decrease in butyrate (-45%) and an increase in propionate (+43%) molar proportions. However, the decrease in ammonia concentration (-42%) observed in the presence of HBS was less than that caused by ivy saponins, either alone or with stevia. Whereas HBS and stevia impacted on bacterial population in terms of community structure, only HBS had an effect in terms of biodiversity (P<0.05). It was concluded that ivy saponins with stevia and the modified saponin HBS had a strong antiprotozoal effect, although they differed in their effects on fermentation parameters and bacteria communities. Ivy saponins combined with an iminosugar

Coordinate Intracellular Expression of Salmonella Genes Induced during Infection

PubMed Central

Heithoff, Douglas M.; Conner, Christopher P.; Hentschel, Ute; Govantes, Fernando; Hanna, Philip C.; Mahan, Michael J.

1999-01-01

Salmonella typhimurium in vivo-induced (ivi) genes were grouped by their coordinate behavior in response to a wide variety of environmental and genetic signals, including pH, Mg2+, Fe2+, and PhoPQ. All of the seven ivi fusions that are induced by both low pH and low Mg2+ (e.g., iviVI-A) are activated by the PhoPQ regulatory system. Iron-responsive ivi fusions include those induced under iron limitation (e.g., entF) as well as one induced by iron excess but only in the absence of PhoP (pdu). Intracellular expression studies showed that each of the pH- and Mg2+-responsive fusions is induced upon entry into and growth within three distinct mammalian cell lines: RAW 264.7 murine macrophages and two cultured human epithelial cell lines: HEp-2 and Henle-407. Each ivi fusion has a characteristic level of induction consistent within all three cell types, suggesting that this class of coordinately expressed ivi genes responds to general intracellular signals that are present both in initial and in progressive stages of infection and may reflect their responses to similar vacuolar microenvironments in these cell types. Investigation of ivi expression patterns reveals not only the inherent versatility of pathogens to express a given gene(s) at various host sites but also the ability to modify their expression within the context of different animal hosts, tissues, cell types, or subcellular compartments. PMID:9922242

Coadministration of Hedera helix L. Extract Enabled Mice to Overcome Insufficient Protection against Influenza A/PR/8 Virus Infection under Suboptimal Treatment with Oseltamivir

PubMed Central

Shim, Aeri; Lee, Bo-Ra; Kwon, Bo-Eun; Song, Hyuk-Hwan; Kim, Yeon-Jeong; Chang, Sun-Young; Jeong, Hyeon Gun; Kim, Jong Geal; Seo, Sang-Uk; Kim, HyunPyo; Kwon, YongSoo; Ko, Hyun-Jeong

2015-01-01

Several anti-influenza drugs that reduce disease manifestation exist, and although these drugs provide clinical benefits in infected patients, their efficacy is limited by the emergence of drug-resistant influenza viruses. In the current study, we assessed the therapeutic strategy of enhancing the antiviral efficacy of an existing neuraminidase inhibitor, oseltamivir, by coadministering with the leaf extract from Hedera helix L, commonly known as ivy. Ivy extract has anti-inflammatory, antibacterial, antifungal, and antihelminthic properties. In the present study, we investigated its potential antiviral properties against influenza A/PR/8 (PR8) virus in a mouse model with suboptimal oseltamivir that mimics a poor clinical response to antiviral drug treatment. Suboptimal oseltamivir resulted in insufficient protection against PR8 infection. Oral administration of ivy extract with suboptimal oseltamivir increased the antiviral activity of oseltamivir. Ivy extract and its compounds, particularly hedrasaponin F, significantly reduced the cytopathic effect in PR8-infected A549 cells in the presence of oseltamivir. Compared with oseltamivir treatment alone, coadministration of the fraction of ivy extract that contained the highest proportion of hedrasaponin F with oseltamivir decreased pulmonary inflammation in PR8-infected mice. Inflammatory cytokines and chemokines, including tumor necrosis factor-alpha and chemokine (C-C motif) ligand 2, were reduced by treatment with oseltamivir and the fraction of ivy extract. Analysis of inflammatory cell infiltration in the bronchial alveolar of PR8-infected mice revealed that CD11b+Ly6G+ and CD11b+Ly6Cint cells were recruited after virus infection; coadministration of the ivy extract fraction with oseltamivir reduced infiltration of these inflammatory cells. In a model of suboptimal oseltamivir treatment, coadministration of ivy extract fraction that includes hedrasaponin F increased protection against PR8 infection that could be

Coadministration of Hedera helix L. Extract Enabled Mice to Overcome Insufficient Protection against Influenza A/PR/8 Virus Infection under Suboptimal Treatment with Oseltamivir.

PubMed

Hong, Eun-Hye; Song, Jae-Hyoung; Shim, Aeri; Lee, Bo-Ra; Kwon, Bo-Eun; Song, Hyuk-Hwan; Kim, Yeon-Jeong; Chang, Sun-Young; Jeong, Hyeon Gun; Kim, Jong Geal; Seo, Sang-Uk; Kim, HyunPyo; Kwon, YongSoo; Ko, Hyun-Jeong

2015-01-01

Several anti-influenza drugs that reduce disease manifestation exist, and although these drugs provide clinical benefits in infected patients, their efficacy is limited by the emergence of drug-resistant influenza viruses. In the current study, we assessed the therapeutic strategy of enhancing the antiviral efficacy of an existing neuraminidase inhibitor, oseltamivir, by coadministering with the leaf extract from Hedera helix L, commonly known as ivy. Ivy extract has anti-inflammatory, antibacterial, antifungal, and antihelminthic properties. In the present study, we investigated its potential antiviral properties against influenza A/PR/8 (PR8) virus in a mouse model with suboptimal oseltamivir that mimics a poor clinical response to antiviral drug treatment. Suboptimal oseltamivir resulted in insufficient protection against PR8 infection. Oral administration of ivy extract with suboptimal oseltamivir increased the antiviral activity of oseltamivir. Ivy extract and its compounds, particularly hedrasaponin F, significantly reduced the cytopathic effect in PR8-infected A549 cells in the presence of oseltamivir. Compared with oseltamivir treatment alone, coadministration of the fraction of ivy extract that contained the highest proportion of hedrasaponin F with oseltamivir decreased pulmonary inflammation in PR8-infected mice. Inflammatory cytokines and chemokines, including tumor necrosis factor-alpha and chemokine (C-C motif) ligand 2, were reduced by treatment with oseltamivir and the fraction of ivy extract. Analysis of inflammatory cell infiltration in the bronchial alveolar of PR8-infected mice revealed that CD11b+Ly6G+ and CD11b+Ly6Cint cells were recruited after virus infection; coadministration of the ivy extract fraction with oseltamivir reduced infiltration of these inflammatory cells. In a model of suboptimal oseltamivir treatment, coadministration of ivy extract fraction that includes hedrasaponin F increased protection against PR8 infection that could be

The origins of informed consent: the International Scientific Commission on Medical War Crimes, and the Nuremburg code.

PubMed

Weindling, P

2001-01-01

The Nuremberg Code has generally been seen as arising from the Nuremberg Medical Trial. This paper examines developments prior to the Trial, involving the physiologist Andrew Conway Ivy and an inter-Allied Scientific Commission on Medical War Crimes. The paper traces the formulation of the concept of a medical war crime by the physiologist John West Thompson, as part of the background to Ivy's code on human experiments of 1 August 1946. It evaluates subsequent responses by the American Medical Association, and by other war crimes experts, notably Leo Alexander, who developed Ivy's conceptual framework. Ivy's interaction with the judges at Nuremberg alerted them to the importance of formulating ethical guidelines for clinical research.

Serial Metabolome Changes in a Prospective Cohort of Subjects with Influenza Viral Infection and Comparison with Dengue Fever.

PubMed

Cui, Liang; Fang, Jinling; Ooi, Eng Eong; Lee, Yie Hou

2017-07-07

Influenza virus infection (IVI) and dengue virus infection (DVI) are major public health threats. Between IVI and DVI, clinical symptoms can be overlapping yet infection-specific, but host metabolome changes are not well-described. Untargeted metabolomics and targeted oxylipinomic analyses were performed on sera serially collected at three phases of infection from a prospective cohort study of adult subjects with either H3N2 influenza infection or dengue fever. Untargeted metabolomics identified 26 differential metabolites, and major perturbed pathways included purine metabolism, fatty acid biosynthesis and β-oxidation, tryptophan metabolism, phospholipid catabolism, and steroid hormone pathway. Alterations in eight oxylipins were associated with the early symptomatic phase of H3N2 flu infection, were mostly arachidonic acid-derived, and were enriched in the lipoxygenase pathway. There was significant overlap in metabolome profiles in both infections. However, differences specific to IVI and DVI were observed. DVI specifically attenuated metabolites including serotonin, bile acids and biliverdin. Additionally, metabolome changes were more persistent in IVI in which metabolites such as hypoxanthine, inosine, and xanthine of the purine metabolism pathway remained significantly elevated at 21-27 days after fever onset. This study revealed the dynamic metabolome changes in IVI subjects and provided biochemical insights on host physiological similarities and differences between IVI and DVI.

Poison Ivy

MedlinePlus

... leaves of the plants. Look Out for Poison Plants These plants can be anywhere — from the woods ... pill or liquid form. Preventing Rashes From Poison Plants The best approach is to avoid getting the ...

Intelligent Visual Input: A Graphical Method for Rapid Entry of Patient-Specific Data

PubMed Central

Bergeron, Bryan P.; Greenes, Robert A.

1987-01-01

Intelligent Visual Input (IVI) provides a rapid, graphical method of data entry for both expert system interaction and medical record keeping purposes. Key components of IVI include: a high-resolution graphic display; an interface supportive of rapid selection, i.e., one utilizing a mouse or light pen; algorithm simplification modules; and intelligent graphic algorithm expansion modules. A prototype IVI system, designed to facilitate entry of physical exam findings, is used to illustrates the potential advantages of this approach.

Breadboard development of a fluid infusion system

NASA Technical Reports Server (NTRS)

Thompson, R. W.

1974-01-01

A functional breadboard of a zero gravity Intravenous Infusion System (IVI) is presented. Major components described are: (1) infusate pack pressurizers; (2) pump module; (3) infusion set; and (4) electronic control package. The IVI breadboard was designed to demonstrate the feasibility of using the parallel solenoid pump and spring powered infusate source pressurizers for the emergency infusion of various liquids in a zero gravity environment. The IVI was tested for flow rate and sensitivity to back pressure at the needle. Results are presented.

Impetigo

MedlinePlus

... is already irritated by another problem, such as eczema , poison ivy , insect bites , and cuts or scrapes . ... injuries (cuts, scrapes, bug bites, etc.), areas of eczema, and rashes such as poison ivy. Keep these ...

Air quality impacts of intercity freight. Volume 1 : guidebook

DOT National Transportation Integrated Search

2000-01-01

Driver error remains the leading cause of highway crashes. Through the Intelligent Vehicle Initiative (IVI), the Department of Transportation hopes to reduce crashes by helping drivers avoid hazardous mistakes. IVI aims to accelerate the development ...

Driving safely into the future with applied technology

DOT National Transportation Integrated Search

1999-10-01

Driver error remains the leading cause of highway crashes. Through the Intelligent Vehicle Initiative (IVI), the Department of Transportation hopes to reduce crashes by helping drivers avoid hazardous mistakes. IVI aims to accelerate the development ...

21 CFR 347.3 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-04-01

... called “lip balm.” Poison ivy, oak, sumac dermatitis. An allergic contact dermatitis due to exposure to plants of the genus Rhus (poison ivy, poison oak, poison sumac), which contain urushiol, a potent skin...

21 CFR 347.3 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-04-01

... called “lip balm.” Poison ivy, oak, sumac dermatitis. An allergic contact dermatitis due to exposure to plants of the genus Rhus (poison ivy, poison oak, poison sumac), which contain urushiol, a potent skin...

21 CFR 347.3 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-04-01

... called “lip balm.” Poison ivy, oak, sumac dermatitis. An allergic contact dermatitis due to exposure to plants of the genus Rhus (poison ivy, poison oak, poison sumac), which contain urushiol, a potent skin...

Vesicles

MedlinePlus

... herpetiformis Chickenpox Contact dermatitis (may be caused by poison ivy) Herpes simplex (cold sores, genital herpes ) Herpes zoster ( ... available for certain conditions that cause vesicles, including poison ivy and cold sores. When to Contact a Medical ...

First Aid: Rashes

MedlinePlus

... for: Parents Kids Teens First Aid: Skin Infections Poison Ivy Erythema Multiforme Hives (Urticaria) Erythema Toxicum Eczema Pityriasis ... Fifth Disease Shingles Diaper Rash Word Find: Skin Poison Ivy Rashes: The Itchy Truth Your Skin Impetigo Ringworm ...

Volvo Trucks field operational test : evaluation of advanced safety systems for heavy truck tractors

DOT National Transportation Integrated Search

2005-02-15

The Intelligent Vehicle Initiative (IVI) was established by the United States Department of Transportation as an integral part of the Intelligent Transportation System (ITS) program. By reducing the probability of motor vehicle collisions, the IVI wa...

In situ changes in the relative abundance of human epidermal cytokine messenger RNA levels following exposure to the poison ivy/oak contact allergen urushiol.

PubMed

Boehm, K D; Yun, J K; Strohl, K P; Trefzer, U; Häffner, A; Elmets, C A

1996-06-01

Abstract: Epidermal keratinocytes in culture have been shown to produce many cytokines, and their proteins have been identified in skin tissue samples. It has therefore been assumed that these cytokines are transcribed in vivo by the epidermis in response to contact allergens. In this report, in situ hybridization was used to detect the messenger RNAs for interleukin-1 alpha (IL-1 alpha), interleukin-1 beta (IL-1 beta) and tumour necrosis factor-alpha (TNF-alpha) in samples of human skin prior to and at various times after application of urushiol, the immunogenic component of poison ivy/oak. In sensitive subjects, IL-1 alpha and TNF-alpha mRNAs showed a progressive increase in transcript levels that paralleled the clinical and histological features of the inflammatory process. The time-course of the IL-1 beta response differed from that of IL-1 alpha and TNF-alpha, in that there was an early (by 6 h after urushiol administration) elevation in IL-1 beta mRNA that occurred before there was evidence of inflammation and had returned to background levels by 72 h when the reaction had reached its peak. In contrast to urushiol-sensitive subjects, urushiol-anergic individuals did not exhibit an increase in IL-1 alpha, IL-1 beta or TNF-alpha mRNA levels. The data provide evidence for an in vivo role for epidermal IL-1 alpha, IL-1 beta and TNF-alpha transcription in the regulation of IL-1 beta and TNF-alpha polypeptide levels in the epidermis in response to this common contact allergen.

Phase II driver survey report: Volvo intelligent vehicle initiative field operational test

DOT National Transportation Integrated Search

2004-10-28

The United States Department of Transportation (USDOT) established an Intelligent Vehicle Initiative (IVI) as a major component of the Intelligent Transportation System (ITS) program. The intent of the IVI is to improve significantly the safety and e...

Hotspot Patterns: The Formal Definition and Automatic Detection of Architecture Smells

DTIC Science & Technology

2015-01-15

serious question for a project manager or architect: how to determine which parts of the code base should be given higher priority for maintenance and...services framework; Hadoop8 is a tool for distributed processing of large data sets; HBase9 is the Hadoop database; Ivy10 is a dependency management tool...answer this question more rigorously, we conducted Pearson Correlation Analysis to test the dependency between the number of issues a file involves

Bacterial infection as assessed by in vivo gene expression

PubMed Central

Heithoff, Douglas M.; Conner, Christopher P.; Hanna, Philip C.; Julio, Steven M.; Hentschel, Ute; Mahan, Michael J.

1997-01-01

In vivo expression technology (IVET) has been used to identify >100 Salmonella typhimurium genes that are specifically expressed during infection of BALB/c mice and/or murine cultured macrophages. Induction of these genes is shown to be required for survival in the animal under conditions of the IVET selection. One class of in vivo induced (ivi) genes, iviVI-A and iviVI-B, constitute an operon that resides in a region of the Salmonella genome with low G+C content and presumably has been acquired by horizontal transfer. These ivi genes encode predicted proteins that are similar to adhesins and invasins from prokaryotic and eukaryotic pathogens (Escherichia coli [tia], Plasmodium falciparum [PfEMP1]) and have coopted the PhoPQ regulatory circuitry of Salmonella virulence genes. Examination of the in vivo induction profile indicates (i) many ivi genes encode regulatory functions (e.g., phoPQ and pmrAB) that serve to enhance the sensitivity and amplitude of virulence gene expression (e.g., spvB); (ii) the biochemical function of many metabolic genes may not represent their sole contribution to virulence; (iii) the host ecology can be inferred from the biochemical functions of ivi genes; and (iv) nutrient limitation plays a dual signaling role in pathogenesis: to induce metabolic functions that complement host nutritional deficiencies and to induce virulence functions required for immediate survival and spread to subsequent host sites. PMID:9023360

Intelligent vehicle initiative : 2002 annual report -- saving lives through advanced vehicle safety technology

DOT National Transportation Integrated Search

2003-05-15

This Annual Report provides an overview of the Intelligent Vehicle Initiatives (IVIs) progress and accomplishments during 2002. The 1998 Transportation Efficiency Act for the 21st Century (TEA-21) authorized IVI as part of the Department of Tra...

Evaluation of the Mack Intelligent Vehicle Field Operational Test: September 2006

DOT National Transportation Integrated Search

2006-09-01

This report presents the final results of an independent evaluation of the U.S. Department of Transportation (USDOT) Mack Intelligent Vehicle Initiative (IVI) Field Operational Test (FOT). The IVI is a cooperative effort to conduct FOTs of advanced i...

Intelligent Vehicle Initiative: Business Plan

DOT National Transportation Integrated Search

1997-11-01

The U.S. Department of Transportation (USDOT) is embarking on a new program called the Intelligent Vehicle Initiative (IVI). The USDOT intends to jointly define the program plan and conduct the IVI in cooperation with the motor vehicle, trucking, and...

IVHS institutional issues and case studies : Travtek case study

DOT National Transportation Integrated Search

1997-11-01

The U.S. Department of Transportation (USDOT) is embarking on a new program called the Intelligent Vehicle Initiative (IVI). The USDOT intends to jointly define the program plan and conduct the IVI in cooperation with the motor vehicle, trucking, and...

π-Extended Isoindigo-Based Derivative: A Promising Electron-Deficient Building Block for Polymer Semiconductors.

PubMed

Xu, Long; Zhao, Zhiyuan; Xiao, Mingchao; Yang, Jie; Xiao, Jian; Yi, Zhengran; Wang, Shuai; Liu, Yunqi

2017-11-22

The exploration of novel electron-deficient building blocks is a key task for developing high-performance polymer semiconductors in organic thin-film transistors. In view of the situation of the lack of strong electron-deficient building blocks, we designed two novel π-extended isoindigo-based electron-deficient building blocks, IVI and F 4 IVI. Owing to the strong electron-deficient nature and the extended π-conjugated system of the two acceptor units, their copolymers, PIVI2T and PF 4 IVI2T, containing 2,2'-bithiophene donor units, are endowed with deep-lying highest occupied molecular orbital (HOMO)/lowest unoccupied molecular orbital (LUMO) energy levels and strong intermolecular interactions. In comparison to PIVI2T, the fluorinated PF 4 IVI2T exhibits stronger intra- and intermolecular interactions, lower HOMO/LUMO energy levels up to -5.74/-4.17 eV, and more ordered molecular packing with a smaller π-π stacking distance of up to 3.53 Å, resulting in an excellent ambipolar transporting behavior and a promising application in logic circuits for PF 4 IVI2T in ambient with hole and electron mobilities of up to 1.03 and 1.82 cm 2 V -1 s -1 , respectively. The results reveal that F 4 IVI is a promising and strong electron-deficient building unit to construct high-performance semiconducting polymers, which provides an insight into the structure-property relationships for the exploration and molecular engineering of excellent electron-deficient building blocks in the field of organic electronics.

76 FR 65109 - New Animal Drugs for Use in Animal Feeds; Melengestrol; Monensin; Tylosin

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-20

.... FDA-2011-N-0003] New Animal Drugs for Use in Animal Feeds; Melengestrol; Monensin; Tylosin AGENCY...) is amending the animal drug regulations to reflect approval of a supplemental abbreviated new animal drug application (ANADA) filed by Ivy Laboratories, Division of Ivy Animal Health, Inc. The...

To twist or poke? A method for identifying usability issues with the rotary controller and touch screen for control of in-vehicle information systems.

PubMed

Harvey, Catherine; Stanton, Neville A; Pickering, Carl A; McDonald, Mike; Zheng, Pengjun

2011-07-01

In-vehicle information systems (IVIS) can be controlled by the user via direct or indirect input devices. In order to develop the next generation of usable IVIS, designers need to be able to evaluate and understand the usability issues associated with these two input types. The aim of this study was to investigate the effectiveness of a set of empirical usability evaluation methods for identifying important usability issues and distinguishing between the IVIS input devices. A number of usability issues were identified and their causal factors have been explored. These were related to the input type, the structure of the menu/tasks and hardware issues. In particular, the translation between inputs and on-screen actions and a lack of visual feedback for menu navigation resulted in lower levels of usability for the indirect device. This information will be useful in informing the design of new IVIS, with improved usability. STATEMENT OF RELEVANCE: This paper examines the use of empirical methods for distinguishing between direct and indirect IVIS input devices and identifying usability issues. Results have shown that the characteristics of indirect input devices produce more serious usability issues, compared with direct devices and can have a negative effect on the driver-vehicle interaction.

Fractional sunburn threshold UVR doses generate equivalent vitamin D and DNA damage in skin types I-VI, but with epidermal DNA damage gradient correlated to skin darkness.

PubMed

Shih, Barbara B; Farrar, Mark D; Cooke, Marcus S; Osman, Joanne; Langton, Abigail K; Kift, Richard; Webb, Ann R; Berry, Jacqueline L; Watson, Rachel E B; Vail, Andy; de Gruijl, Frank R; Rhodes, Lesley E

2018-05-03

Public health guidance recommends limiting sun-exposure to sub-sunburn levels, but it's unknown whether these can gain vitamin D (for musculoskeletal health) whilst avoiding epidermal DNA damage (initiates skin cancer). Well-characterised healthy humans of all skin types (I-VI; lightest to darkest skin) were exposed to a low dose-series of solar simulated UVR of 20-80% their individual sunburn threshold dose (minimal erythemal dose, MED). Significant UVR dose-responses were seen for serum 25(OH)D and whole epidermal CPD, with as little as 0.2 MED concurrently producing 25(OH)D and CPD. Notably, fractional MEDs generated equivalent levels of whole epidermal CPD and 25(OH)D across all skin types. Crucially, we demonstrated an epidermal gradient of CPD formation strongly correlated with skin darkness (r=0.74; P<0.0001), which reflected melanin content and revealed increasing protection across the skin types, ranging from darkest skin, where high CPD levels occurred superficially with none in the germinative basal layer, through to lightest skin where CPD were induced evenly across the epidermal depth. Darker skin people can be encouraged to utilise sub-sunburn UVR-exposure to enhance their vitamin D. In lighter skin people, basal cell damage occurs concurrent with vitamin D synthesis at exquisitely low UVR levels, providing an explanation for their high skin cancer incidence; greater caution is required. Copyright © 2018 The Authors. Published by Elsevier Inc. All rights reserved.

SPECIAL ISSUE VETERINARY IMMUNOLOGY IMMUNOPATHOLOGY: PROCEEDINGS 8TH INTERNATIONAL VETERINARY IMMUNOLOGY SYMPOSIUM

USDA-ARS?s Scientific Manuscript database

This is the Special Issue of Vet. Immunol. Immunopathol. that summarizes the 8th International Veterinary Immunology Symposium (8 th IVIS) held August 15th-19th, 2007, in Ouro Preto, Brazil. The 8 th IVIS highlighted the importance of veterinary immunology for animal health, vaccinology, reproducti...

76 FR 60721 - New Animal Drugs for Use in Animal Feeds; Melengestrol; Monensin

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-30

.... FDA-2011-N-0003] New Animal Drugs for Use in Animal Feeds; Melengestrol; Monensin AGENCY: Food and... amending the animal drug regulations to reflect approval of a supplemental abbreviated new animal drug application (ANADA) filed by Ivy Laboratories, Division of Ivy Animal Health, Inc. The supplemental ANADA...

75 FR 20917 - New Animal Drugs for Use in Animal Feeds; Melengestrol, Monensin, and Ractopamine

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-22

.... FDA-2010-N-0002] New Animal Drugs for Use in Animal Feeds; Melengestrol, Monensin, and Ractopamine... (FDA) is amending the animal drug regulations to reflect approval of a supplemental abbreviated new animal drug application (ANADA) filed by Ivy Laboratories, Div. of Ivy Animal Health, Inc. The...

Behavior-dependent specialization of identified hippocampal interneurons

PubMed Central

Lapray, Damien; Lasztoczi, Balint; Lagler, Michael; Viney, Tim James; Katona, Linda; Valenti, Ornella; Hartwich, Katja; Borhegyi, Zsolt; Somogyi, Peter; Klausberger, Thomas

2012-01-01

A large variety of GABAergic interneurons control information processing in hippocampal circuits governing the formation of neuronal representations. Whether distinct hippocampal interneuron types contribute differentially to information-processing during behavior is not known. We employed a novel technique for recording and labeling interneurons and pyramidal cells in drug-free, freely-moving rats. Recorded parvalbumin-expressing basket interneurons innervate somata and proximal pyramidal cell dendrites, whereas nitric-oxide-synthase- and neuropeptide-Y-expressing ivy cells provide synaptic and extrasynaptic dendritic modulation. Basket and ivy cells showed distinct spike timing dynamics, firing at different rates and times during theta and ripple oscillations. Basket but not ivy cells changed their firing rates during movement, sleep and quiet wakefulness, suggesting that basket cells coordinate cell assemblies in a behavioral state-contingent manner, whereas persistently-firing ivy cells might control network excitability and homeostasis. Different interneuron types provide GABA to specific subcellular domains at defined times and rates, thus differentially controlling network activity during behavior. PMID:22864613

Using Interactive Video Instruction To Enhance Public Speaking Instruction.

ERIC Educational Resources Information Center

Cronin, Michael W.; Kennan, William R.

Noting that interactive video instruction (IVI) should not and cannot replace classroom instruction, this paper offers an introduction to interactive video instruction as an innovative technology that can be used to expand pedagogical opportunities in public speaking instruction. The paper: (1) defines the distinctive features of IVI; (2) assesses…

Comparison of Shear Shredder with Hammermill for Size Reduction of Navy Solid Waste

DTIC Science & Technology

1986-03-01

IVY CASE) IS. $1,249,650 $1,002,420 11" MAJOR EQUIPMENT ,EPL-..EMENT COST $ $737,660 $499,100 144 115 KAXINL’ PRACTICAL PROJECT LIfE YEARS 20 20 116...DC DEFFUELSUPPCEN DFSC-OWE, Alexandria VA DLSIE Army Logistics Mgt Center, Fort Lee . VA DOE Whid’Ocean Tech Div. Tobacco. ’AD ENVIRONMENTAL PROTECHION...UNIVERSITY W.B. Ledbetter . College Station. TX UNIVERSITY OF CALIFORNIA Energy Engineer, Davis CA; Prof E.A. Pearson. Berkeley, CA; CE Dept (Mitchell

Reference Book of Nuclear Testing Contractors 1945-1965. Revision 1

DTIC Science & Technology

1987-05-30

Corps of Engineers W49-129-Eng-148 Armour Research Foundation of Illinois Institute of Technology Project 3.3 AF 33(038)9761 (Air Material Command...VnVnPT^^flW1iVi’U’*J ’^." v*-" I*H*JI w VI«HIIWIWI^I ^ -i« - BUSTER JANGLE Armour Research Foundation Illinois Institute of Technology Chicago, IL...v TUMBLER SNAPPER Armour Research Foundation (ARF) AF 33(616)3218 Bendix Corp/Bendix Aviation Aviation Pacific Division Development

Air Force Public Affairs: The Four Models of Public Relations and Excellence in Public Relations

DTIC Science & Technology

1991-01-01

1984), publicity was used to fight large business organizations. Journalists who exposed corrupt business practices were called "muckrakers." Ivy Lee , a...master’s thesis, University of Maryland, College Park, Md. Hiebert, R.E. (1966). Courtier %o the crowd: The story of Ivy Lee and the development of public

Echolalic Responses by a Child with Autism to Four Experimental Conditions of Sociolinguistic Input.

ERIC Educational Resources Information Center

Violette, Joseph; Swisher, Linda

1992-01-01

The immediate verbal imitations (IVIs) of a boy (age five) with autism and echolalia were studied, with variables of linguistic familiarity and instructor's style of directiveness being manipulated. The occurrence of IVIs was related to uncertain or informative events, and was significantly greater when lexical stimuli were unknown and presented…

Poison Ivy Treatment

MedlinePlus

... skin reactions. These skin reactions are forms of contact dermatitis. Treatment Treating reactions to poison ivy—the most frequent of these forms of contact dermatitis—is a straightforward matter. Prevention is the best ...

Poison Ivy Dermatitis

MedlinePlus

... rashes need treatment to ease the misery and disability they cause. The very first time this rash ... the compresses and apply only the cream. Cream applied before the blisters and swelling go down are ...

Ocular side effects following intravitreal injection therapy for retinoblastoma: a systematic review.

PubMed

Smith, Stephen J; Smith, Brian D; Mohney, Brian G

2014-03-01

To describe the ocular side effects in patients receiving intravitreal injection therapy (IViT) for retinoblastoma. PubMed (1946-present), Scopus (all years), Science Citation Index (1900-present) and Conference Proceedings Citation Index-Science (1990-present) electronic databases were searched to identify all published reports of therapeutic intravitreal injections for retinoblastoma in humans. Ten studies with original IViT ocular side effect data were included in this systematic review. In these combined reports, a total of 1287 intravitreal injections were given to 306 eyes of 295 patients, with a mean follow-up of 74.1 months. Two hundred sixty-one (88.5%) patients received comparatively standard melphalan IViT doses (8-30 mcg). Ocular side effects occurred in 38 patients (17 significant, 21 minor). The proportion of patients experiencing potentially significant ocular side effects following standard melphalan IViT regimens was 0.031 (8/261; 95% CI 0.013 to 0.06). The side effects of these eight included iris atrophy in three, two each with chorioretinal atrophy and vitreous haemorrhage and one with retinal detachment. Of the other nine patients with significant complications, five experienced sight-threatening complications following dramatic dose escalations (four with melphalan, one with thiotepa), three experienced complications that are commonly associated with concurrent therapies given to these patients and one had a retinal detachment. Of the 61 patients receiving IViT via safety-enhancing injection techniques, all six significant side effects were either attributed to the therapeutic dose or confounded by concurrent treatments. Significant ocular complications following IViT for retinoblastoma are uncommon, and this risk may be reduced further by the use of careful injection technique and standard dosing regimens. Care must be taken in the dosing of intravitreal treatments to avoid potentially irreversible vision loss.

Improving Warfighters’ Sustainment and Performance in Extreme Environmental Conditions

DTIC Science & Technology

2008-02-18

Physiol, 485 ( Pt 2) (1995) 525-530. 9. Puchowicz,M.A., Xu,K., Sun,X., Ivy,A., Emancipator,D., and LaManna,J.C., Diet-induced ketosis increases...2002) 1131-1139. 27. Puchowicz,M.A., Xu,K., Sun,X., Ivy,A., Emancipator,D., and LaManna,J.C., Diet-induced ketosis increases capillary density

Towards a More Complete Picture: Dissimilatory Metal Reduction by Anaeromyxobacter Species

DOE Office of Scientific and Technical Information (OSTI.GOV)

Loeffler, Frank E.

2005-06-01

Towards a More Complete Picture: Dissimilatory Metal Reduction by Anaeromyxobacter Species The overarching goal of this 3-year project is to explore uranium reduction in Anaeromyxobacter species. Specifically, we explore the physiological requirements of available Anaeromyxobacter isolates, design molecular biology tools to detect and quantify Anaeromyxobacter in pure cultures, consortia, and environmental samples, assess their diversity, distribution, and abundance in the environment, including DOE sites, and attempt the isolation of additional Anaeromyxobacter species from the Oak Ridge Field Research Center (FRC). The performers on this project include Frank Loeffler (PI), Robert Sanford (Co-PI), Qingzhong Wu (postdoc), Sara Henry (graduate student withmore » fellowship, no charges to NABIR project), Ivy Thomson (graduate student, no charges to NABIR project), and Ryan Wagner (''Special Topics'' bioinformatics undergraduate student, no charges to NABIR project). Exploratory MALDI-TOF MS experiments for the specific detection of Anaeromyxobacter species were performed by Kerry Preston (graduate student, no charges to NABIR project).« less

Phase 2 Site Investigations Report. Volume 2 of 3: site-Specific Investigations

DTIC Science & Technology

1994-09-01

overstory regeneration. In addition, poison ivy and Virginia creeper are common vines. Various asters, grasses, and goldenrods comprise the sparsely...and silky dogwood. Poison ivy dominates the ground cover. In general these areas combine several distinct upland habitats which support wildlife...hemlock, speckled alder, red maple saplings and a variety of herbaceous and emergent plants, such as water lilies, cattails, jewelweed , sensitive fern

Safety implications of providing real-time feedback to distracted drivers.

PubMed

Donmez, Birsen; Boyle, Linda Ng; Lee, John D

2007-05-01

A driving simulator study was conducted to assess whether real-time feedback on a driver's state can influence the driver's interaction with in-vehicle information systems (IVIS). Previous studies have shown that IVIS tasks can undermine driver safety by increasing driver distraction. Thus, mitigating driver distraction using a feedback mechanism appears promising. This study was designed to test real-time feedback that alerts drivers based on their off-road eye glances. Feedback was displayed in two display locations (vehicle-centered, and IVIS-centered) to 16 young and 13 middle-aged drivers. Distraction was observed as problematic for both age groups with delayed responses to a lead vehicle-braking event as indicated by delayed accelerator releases. Significant benefits were not observed for braking and steering behavior for this experiment, but there was a significant change in drivers' interaction with IVIS. When given feedback on their distracted state, drivers looked at the in-vehicle display less frequently regardless of where feedback was displayed in the vehicle. This indicates that real-time feedback based on the driver state can positively alter driver's engagement in distracting activities, helping them attend better to the roadway.

Skill acquisition while operating in-vehicle information systems: interface design determines the level of safety-relevant distractions.

PubMed

Jahn, Georg; Krems, Josef F; Gelau, Christhard

2009-04-01

This study tested whether the ease of learning to use human-machine interfaces of in-vehicle information systems (IVIS) can be assessed at standstill. Assessing the attentional demand of IVIS should include an evaluation of ease of learning, because the use of IVIS at low skill levels may create safety-relevant distractions. Skill acquisition in operating IVIS was quantified by fitting the power law of practice to training data sets collected in a driving study and at standstill. Participants practiced manual destination entry with two route guidance systems differing in cognitive demand. In Experiment 1, a sample of middle-aged participants was trained while steering routes of varying driving demands. In Experiment 2, another sample of middle-aged participants was trained at standstill. In Experiment 1, display glance times were less affected by driving demands than by total task times and decreased at slightly higher speed-up rates (0.02 higher on average) than task times collected at standstill in Experiment 2. The system interface that minimized cognitive demand was operated more quickly and was easier to learn. Its system delays increased static task times, which still predicted 58% of variance in display glance times compared with even 76% for the second system. The ease of learning to use an IVIS interface and the decrease in attentional demand with training can be assessed at standstill. Fitting the power law of practice to static task times yields parameters that predict display glance times while driving, which makes it possible to compare interfaces with regard to ease of learning.

Recommended oral sodium bicarbonate administration for urine alkalinization did not affect the concentration of mitomycin-C in non-muscle invasive bladder cancer patients.

PubMed

Seo, Ho Kyung; Kim, Sung Han; Ahn, Kyung-Ohk; Lee, Sang-Jin; Park, Weon Seo; Kim, Sohee; Hwang, Sang-Hyun; Lee, Do Hoon; Joung, Jae Young; Chung, Jinsoo; Joo, Jungnam; Jeong, Kyung-Chae

2017-11-10

Sodium bicarbonate has been reported to maximize the efficacy of intravesical instillation of mitomycin-C (IVI-MMC) therapy by urine alkalinization in non-muscle-invasive bladder cancer (NMIBC). This study aimed to analyze the changes in MMC concentration according to urinary pH and evaluate the efficacy of sodium bicarbonate to maintain the concentration of active form of MMC during IVI-MMC. We prospectively enrolled 26 patients with NMIBC after transurethral resection of bladder tumor. Patients with very high-risk and low-risk NMIBC were excluded. Urinary creatinine, volume, pH, and concentrations of MMC and its degraded form were measured immediately before and after IVI-MMC. The patients were administered 1.5 g of oral sodium bicarbonate during the preceding evening, in the morning, and immediately before the fourth cycle of the six-cycle IVI-MMC. The correlation between MMC concentration and urinary pH changes was explored with or without oral bicarbonate therapy. Recurrence without progression to muscle-invasive disease was noted in 4 of 26 patients in a 23.7-month follow-up. The mean urinary pH before and after the therapy increased from 6.03 to 6.50, and 6.46 to 7.24, without or with oral SB therapy, respectively. Despite this increase, the concentration of active form of MMC did not change significantly. No correlation was found between urinary pH and MMC concentration. Urine alkalinization by SB administration did not maintain the high concentration of urinary MMC. Urine alkalinization by sodium bicarbonate administration for IVI-MMC did not maintain the high concentration of active urinary MMC in NMIBC.

Survey of intravitreal injection techniques and treatment protocols among retina specialists in Canada.

PubMed

Xing, Lin; Dorrepaal, Stephen J; Gale, Jeffrey

2014-06-01

To describe intravitreal injection (IVI) techniques and treatment protocols by retina specialists in Canada from August 1, 2012, to October 1, 2012. Cross-sectional survey. All fellowship-trained retina specialists across Canada, as identified from the Canadian Ophthalmological Society directory and the Canadian Retina and Vitreous Society directory. An anonymous 28-question survey was sent to 125 retina specialists across Canada by email. Reminder letters were sent by email, mail, and fax as necessary. A total of 75 (63%) retina specialists responded to the survey. Most IVIs were performed in the office. Most surgeons did not use gloves (61%), sterile draping (91%), or surgical mask (71%). Antisepsis was used on conjunctiva by 100% and on periocular skin by 48%. Nearly all specialists used a sterile lid speculum (91%). Common anaesthetics included topical proparacaine or lidocaine drops (90%), topical lidocaine gel (25%), topical pledget (23%), and subconjunctival lidocaine injections (23%). Most (83%) dilate the pupil before IVI. Prophylactic topical antibiotics were used by 43%; 50% of these were started immediately after IVI. Injection location was estimated by visualization by 45%. A majority (63%) inject inferotemporally. Anterior chamber paracentesis was performed routinely by 5%. Optic nerve perfusion was formally assessed by 48%. The most common treatment protocol for age-related macular degeneration was treat and extend. For both diabetic and retinal vein occlusion-related macular edema, the most common protocol was 3 initial monthly injections with PRN follow-up. A wide variety of IVI practice patterns exist in terms of aseptic technique, anaesthetics, prophylactic antibiotics, postinjection monitoring, and treatment protocol. Copyright © 2014 Canadian Ophthalmological Society. Published by Elsevier Inc. All rights reserved.

Endophthalmitis after intravitreal injections. Incidence, management and prognosis.

PubMed

Tarragó, R; Olea, J L; Ramírez, C; Escudero, L

2017-03-01

To assess the rate of endophthalmitis after intravitreal injection (IVI) in a «clean room» of a single health centre, following the guidelines of the Spanish Vitreo-Retinal Society (SERV). An analysis was performed on the culture specimens, response to treatment, and final outcomes (guidelines). A retrospective, observational study was conducted on a consecutive case series of patients diagnosed with infectious endophthalmitis after IVI in a single health centre between 2010 and 2015. Intravitreal and systemic treatment was given following the SERV guidelines. The patients were followed up the case was resolved. There were 5 cases of endophthalmitis out of 9467 IVI (incidence 0.053%). Positive cultures were obtained in aqueous and/or vitreous fluid in all cases, with Staphylococcus epidermidis being involved in 4 out of 5 cases. In 2 cases, final visual acuity was non-light perception due to intractable retinal detachments after resolution of the infectious process. IVI performed in a «clean room» have a low incidence of endophthalmitis. The most common infectious agent was Staphylococcus species. In 2 cases the functional prognosis was poor. Copyright © 2016 Sociedad Española de Oftalmología. Publicado por Elsevier España, S.L.U. All rights reserved.

In vitro screening of natural feed additives from crustaceans, diatoms, seaweeds and plant extracts to manipulate rumen fermentation.

PubMed

Belanche, Alejandro; Ramos-Morales, Eva; Newbold, C Jamie

2016-07-01

Eight natural products from animal, unicellular algae, brown seaweed and plant origins were chosen according to their theoretical antimicrobial activity: Diatomaceous earths (DE), insoluble chitosan (ICHI), soluble chitosan (CHI), seaweed meal (SWM), Ascophyllum nodosum (ASC), Laminaria digitata (LAM), neem oil (NOIL) and an ivy fruit extract rich in saponins (IVY). Dose-response incubations were conducted to determine their effect on rumen fermentation pattern and gas production, while their anti-protozoal activity was tested using (14) C-labelled bacteria. DE, SWM, NOIL and ICHI had very small effects on rumen function when used at inclusion rate up to 2 g L(-1) . ASC had anti-protozoal effects (up to -23%) promoting a decrease in gas production and methanogenesis (-15%). LAM increased VFA production (+7%) and shifted from butyrate to acetate. CHI also shifted fermentation towards propionate production and lower methane (-23%) and protozoal activity (-56%). IVY decreased protozoal activity (-39%) and ammonia concentration (-56%), as well as increased feed fermentation (+11% VFA concentration) and shifted from acetate to propionate production. ASC, LAM, CHI and IVY showed promising potential in vitro as feed additives to improve rumen function, thus more research is needed to investigate their mode of action in the rumen microbial ecosystem. © 2015 Society of Chemical Industry. © 2015 Society of Chemical Industry.

Poison ivy - oak - sumac

MedlinePlus

... an allergic reaction that results from touching the sap of these plants. The sap may be on the plant, in the ashes ... garden tools, and sports equipment. Small amounts of sap can remain under a person's fingernails for several ...

Poison Ivy/Oak/Sumac

MedlinePlus

... burning, or blistering. Severe, widespread rashes require medical treatment. Signs and Symptoms an itchy red rash that appears within 4 hours to 4 days after touching the plant oil blisters that ooze clear fluid bumps and ...

Comprehensive characterizations of nanoparticle biodistribution following systemic injection in mice

NASA Astrophysics Data System (ADS)

Liao, Wei-Yin; Li, Hui-Jing; Chang, Ming-Yao; Tang, Alan C. L.; Hoffman, Allan S.; Hsieh, Patrick C. H.

2013-10-01

Various nanoparticle (NP) properties such as shape and surface charge have been studied in an attempt to enhance the efficacy of NPs in biomedical applications. When trying to undermine the precise biodistribution of NPs within the target organs, the analytical method becomes the determining factor in measuring the precise quantity of distributed NPs. High performance liquid chromatography (HPLC) represents a more powerful tool in quantifying NP biodistribution compared to conventional analytical methods such as an in vivo imaging system (IVIS). This, in part, is due to better curve linearity offered by HPLC than IVIS. Furthermore, HPLC enables us to fully analyze each gram of NPs present in the organs without compromising the signals and the depth-related sensitivity as is the case in IVIS measurements. In addition, we found that changing physiological conditions improved large NP (200-500 nm) distribution in brain tissue. These results reveal the importance of selecting analytic tools and physiological environment when characterizing NP biodistribution for future nanoscale toxicology, therapeutics and diagnostics.Various nanoparticle (NP) properties such as shape and surface charge have been studied in an attempt to enhance the efficacy of NPs in biomedical applications. When trying to undermine the precise biodistribution of NPs within the target organs, the analytical method becomes the determining factor in measuring the precise quantity of distributed NPs. High performance liquid chromatography (HPLC) represents a more powerful tool in quantifying NP biodistribution compared to conventional analytical methods such as an in vivo imaging system (IVIS). This, in part, is due to better curve linearity offered by HPLC than IVIS. Furthermore, HPLC enables us to fully analyze each gram of NPs present in the organs without compromising the signals and the depth-related sensitivity as is the case in IVIS measurements. In addition, we found that changing physiological

Intraosseous Hydroxocobalamin in the Treatment of Acute, Severe Cyanide Induced Cardiotoxicity in a Swine (Sus Scrofa) Model - An Alternate Administration Route for Chemical Mass Casualties

DTIC Science & Technology

2012-04-05

Ut:IVI:I... I 11:111VI:> Hydroxocobalamin, hypotension, cyanide, poisoning , intraosseous, Vitamin B 12a, Vitamin B 12 I 1:). :>CI...U I111 T L.L~:>:>II...34II...A I IUIII Ul": I I. LIIVIII ~II UN Ur- I 0. IIIUIVItl1:11 I ::1a . 1\\I~ IVI I: ur- 111:.:>t’UN:>It:ILC 1ŕ:11:>UN II. 111:1"UI1 I D.Ati:>II1~L.I c

Environmental Impact Study of the Northern Section of the Upper Mississippi River. Pool 9.

DTIC Science & Technology

1973-11-01

Poison Ivy are the most common shrub layer vegetation, although neither is abundant in the forest proper. Vine form Poison Ivy, Virginia Creeper...Parthenocissus sp.), Wild Grape (Vitis sp.) and Smilax sp. are the common woody vines . The high unshaded edges of running sloughs in the forest areas...the forest edge, or be succeeded by 1a shrub willow zone, which ends abruptly at the forest edge. The forest 4margin is most often dominated by red or

Nuremberg and the issue of wartime experiments on US prisoners. The Green Committee.

PubMed

Harkness, J M

1996-11-27

Defense attorneys at the Nuremberg Medical Trial argued that no ethical difference existed between experiments in Nazi concentration camps and research in US prisons. Investigations that had taken place in an Illinois prison became an early focus of this argument. Andrew C. Ivy, MD, whom the American Medical Association had selected as a consultant to the Nuremberg prosecutors, responded to courtroom criticism of research in his home state by encouraging the Illinois governor to establish a committee to evaluate prison research. The governor named a committee and accepted Ivy's offer to chair the panel. Late in the trial, Ivy testified--drawing on the authority of this committee--that research on US prisoners was ethically ideal. However, the governor's committee had never met. After the trial's conclusion, the committee report was published in JAMA, where it became a source of support for experimentation on prisoners.

Subfoveal Choroidal Thickness as a Potential Predictor of Clinical Response to Stereotactic Radiotherapy for Neovascular Age-Related Macular Degeneration.

PubMed

Ranjbar, Mahdy; Kurz, Maximilian; Holzhey, Annekatrin; Rades, Dirk; Grisanti, Salvatore

2018-05-01

Stereotactic radiotherapy (SRT) is a new adjuvant treatment modality that has been shown to reduce the need for repetitive intravitreal injections (IVIs) in patients with neovascular age-related macular degeneration (nAMD). The authors aimed to determine baseline predictors of clinical response to SRT. This was a retrospective, observational case series of patients with nAMD who underwent SRT and subsequently had at least 12 months of complete follow-up. After SRT and one mandatory IVI, patients were examined every 4 weeks and received further treatment on a pro re nata basis. Examination included enhanced depth imaging spectral-domain optical coherence tomography (SD-OCT) to measure subfoveal choroidal thickness (SFCT) and central macular thickness (CMT). Patients' data were retrieved from medical records and included demographics, disease duration, lesion size, best-corrected visual acuity (BCVA), previous number of IVIs, and type of drug applied. A total of 35 eyes of 35 patients (76.23 years ± 7.05 years) were included, and 21 eyes (60%) responded well to SRT. The annual injection rate decreased from 6.86 before SRT to 3.46 afterward, whereas BCVA improved from 0.49 logMAR at baseline to 0.37 logMAR at final follow-up. From a morphologic point of view, CMT and SFCT decreased by 71 μm and 37 μm, respectively, at 12-month follow-up compared to baseline. Of all investigated parameters, only SFCT proved to be significant, as a higher baseline SFCT was found to be a strong negative predictor for the number of IVIs needed after SRT (regression coefficient: -0.678; P < .001). Baseline SFCT may help predict which patients with nAMD will respond more favorably to SRT. The authors found eyes with a thicker baseline SFCT needed fewer IVIs after SRT. [Ophthalmic Surg Lasers Imaging Retina. 2018;49:320-328.]. Copyright 2018, SLACK Incorporated.

Expression of lysozymes from Erwinia amylovora phages and Erwinia genomes and inhibition by a bacterial protein.

PubMed

Müller, Ina; Gernold, Marina; Schneider, Bernd; Geider, Klaus

2012-01-01

Genes coding for lysozyme-inhibiting proteins (Ivy) were cloned from the chromosomes of the plant pathogens Erwinia amylovora and Erwinia pyrifoliae. The product interfered not only with activity of hen egg white lysozyme, but also with an enzyme from E. amylovora phage ΦEa1h. We have expressed lysozyme genes from the genomes of three Erwinia species in Escherichia coli. The lysozymes expressed from genes of the E. amylovora phages ΦEa104 and ΦEa116, Erwinia chromosomes and Arabidopsis thaliana were not affected by Ivy. The enzyme from bacteriophage ΦEa1h was fused at the N- or C-terminus to other peptides. Compared to the intact lysozyme, a His-tag reduced its lytic activity about 10-fold and larger fusion proteins abolished activity completely. Specific protease cleavage restored lysozyme activity of a GST-fusion. The bacteriophage-encoded lysozymes were more active than the enzymes from bacterial chromosomes. Viral lyz genes were inserted into a broad-host range vector, and transfer to E. amylovora inhibited cell growth. Inserted in the yeast Pichia pastoris, the ΦEa1h-lysozyme was secreted and also inhibited by Ivy. Here we describe expression of unrelated cloned 'silent' lyz genes from Erwinia chromosomes and a novel interference of bacterial Ivy proteins with a viral lysozyme. Copyright © 2012 S. Karger AG, Basel.

Flood-inundation maps for Suwanee Creek from the confluence of Ivy Creek to the Noblin Ridge Drive bridge, Gwinnett County, Georgia

USGS Publications Warehouse

Musser, Jonathan W.

2012-01-01

Digital flood-inundation maps for a 6.9-mile reach of Suwanee Creek, from the confluence of Ivy Creek to the Noblin Ridge Drive bridge, were developed by the U.S. Geological Survey (USGS) in cooperation with Gwinnett County, Georgia. The inundation maps, which can be accessed through the USGS Flood Inundation Mapping Science Web site at http://water.usgs.gov/osw/flood_inundation/, depict estimates of the areal extent and depth of flooding corresponding to selected water levels (stages) at the USGS streamgage at Suwanee Creek at Suwanee, Georgia (02334885). Current stage at this USGS streamgage may be obtained at http://waterdata.usgs.gov/ and can be used in conjunction with these maps to estimate near real-time areas of inundation. The National Weather Service (NWS) is incorporating results from this study into the Advanced Hydrologic Prediction Service (AHPS) flood-warning system (http://water.weather.gov/ahps/). The NWS forecasts flood hydrographs at many places that commonly are collocated at USGS streamgages. The forecasted peak-stage information for the USGS streamgage at Suwanee Creek at Suwanee (02334885), available through the AHPS Web site, may be used in conjunction with the maps developed in this study to show predicted areas of flood inundation. A one-dimensional step-backwater model was developed using the U.S. Army Corps of Engineers HEC-RAS software for Suwanee Creek and was used to compute flood profiles for a 6.9-mile reach of the creek. The model was calibrated using the most current stage-discharge relations at the Suwanee Creek at Suwanee streamgage (02334885). The hydraulic model was then used to determine 19 water-surface profiles for flood stages at the Suwanee Creek streamgage at 0.5-foot intervals referenced to the streamgage. The profiles ranged from just above bankfull stage (7.0 feet) to approximately 1.7 feet above the highest recorded water level at the streamgage (16.0 feet). The simulated water-surface profiles were then combined

Management of iatrogenic crystalline lens injury occurred during intravitreal injection.

PubMed

Erdogan, Gurkan; Gunay, Betul Onal; Unlu, Cihan; Gunay, Murat; Ergin, Ahmet

2016-08-01

To evaluate the approach to management of iatrogenic crystalline lens injury occurred during intravitreal injection (IVI). The patients who were managed operatively or followed-up without intervention after the iatrogenic lens injury due to IVI were included in the study. Capsular breaks remained either quiescent or resulted in cataract formation in the patients with inadvertent crystalline lens capsule damage. Phacoemulsification surgery was performed in patients with cataract formation with lower fluidic settings. A total of 9 cases included in the study. Seven cases underwent phacoemulsification with intraocular lens implantation. Two cases remained as quiescent lens injury during the follow-up. In 2 cases, dislocation of lens fragments occurred during phacoemulsification where pars plana vitrectomy was performed at the same session. After iatrogenic crystalline lens injury, capsular damage could remain quiescent or progress to cataract formation. Although phacoemulsification surgery can be performed with appropriate parameters, lens fragment dislocation can be observed in cases with traumatic lens damage secondary to IVI.

Occurrence of intraocular air bubbles during intravitreal injections for retinopathy of prematurity.

PubMed

Sukgen, Emine Alyamac; Gunay, Murat; Kocluk, Yusuf

2017-02-01

This study aims to present five cases with retinopathy of prematurity (ROP) who were found to have intraocular air bubbles after intravitreal injection (IVI) treatment. The medical records of 148 infants who underwent IVI for ROP were retrospectively reviewed and the ones who demonstrated post-injection intraocular air bubble formation were recruited. Of the 148 patients (31 babies received ranibizumab, 20 babies received aflibercept, 97 babies received bevacizumab), five were found to have intraocular air bubbles right after the IVI. Two infants received intravitreal ranibizumab and three received intravitreal bevacizumab injections. Although intraocular pressure increased temporarily, no intraocular sterile or infective reactions were observed in the postoperative period. The air bubble was found to resorb spontaneously within 72 h. The occurrence rate of the intravitreal air bubbles in our series was 3.37 % despite previously not been reported in the literature. Due to the intravitreal air injection risk, it is important to be more careful while preparing the intravitreal medication before treatment in premature babies.

Invasive Shrub Mapping in an Urban Environment from Hyperspectral and LiDAR-Derived Attributes

PubMed Central

Chance, Curtis M.; Coops, Nicholas C.; Plowright, Andrew A.; Tooke, Thoreau R.; Christen, Andreas; Aven, Neal

2016-01-01

Proactive management of invasive species in urban areas is critical to restricting their overall distribution. The objective of this work is to determine whether advanced remote sensing technologies can help to detect invasions effectively and efficiently in complex urban ecosystems such as parks. In Surrey, BC, Canada, Himalayan blackberry (Rubus armeniacus) and English ivy (Hedera helix) are two invasive shrub species that can negatively affect native ecosystems in cities and managed urban parks. Random forest (RF) models were created to detect these two species using a combination of hyperspectral imagery, and light detection and ranging (LiDAR) data. LiDAR-derived predictor variables included irradiance models, canopy structural characteristics, and orographic variables. RF detection accuracy ranged from 77.8 to 87.8% for Himalayan blackberry and 81.9 to 82.1% for English ivy, with open areas classified more accurately than areas under canopy cover. English ivy was predicted to occur across a greater area than Himalayan blackberry both within parks and across the entire city. Both Himalayan blackberry and English ivy were mostly located in clusters according to a Local Moran’s I analysis. The occurrence of both species decreased as the distance from roads increased. This study shows the feasibility of producing highly accurate detection maps of plant invasions in urban environments using a fusion of remotely sensed data, as well as the ability to use these products to guide management decisions. PMID:27818664

Real-Time Impact Visualization Inspection of Aerospace Composite Structures with Distributed Sensors.

PubMed

Si, Liang; Baier, Horst

2015-07-08

For the future design of smart aerospace structures, the development and application of a reliable, real-time and automatic monitoring and diagnostic technique is essential. Thus, with distributed sensor networks, a real-time automatic structural health monitoring (SHM) technique is designed and investigated to monitor and predict the locations and force magnitudes of unforeseen foreign impacts on composite structures and to estimate in real time mode the structural state when impacts occur. The proposed smart impact visualization inspection (IVI) technique mainly consists of five functional modules, which are the signal data preprocessing (SDP), the forward model generator (FMG), the impact positioning calculator (IPC), the inverse model operator (IMO) and structural state estimator (SSE). With regard to the verification of the practicality of the proposed IVI technique, various structure configurations are considered, which are a normal CFRP panel and another CFRP panel with "orange peel" surfaces and a cutout hole. Additionally, since robustness against several background disturbances is also an essential criterion for practical engineering demands, investigations and experimental tests are carried out under random vibration interfering noise (RVIN) conditions. The accuracy of the predictions for unknown impact events on composite structures using the IVI technique is validated under various structure configurations and under changing environmental conditions. The evaluated errors all fall well within a satisfactory limit range. Furthermore, it is concluded that the IVI technique is applicable for impact monitoring, diagnosis and assessment of aerospace composite structures in complex practical engineering environments.

Real-Time Impact Visualization Inspection of Aerospace Composite Structures with Distributed Sensors

PubMed Central

Si, Liang; Baier, Horst

2015-01-01

For the future design of smart aerospace structures, the development and application of a reliable, real-time and automatic monitoring and diagnostic technique is essential. Thus, with distributed sensor networks, a real-time automatic structural health monitoring (SHM) technique is designed and investigated to monitor and predict the locations and force magnitudes of unforeseen foreign impacts on composite structures and to estimate in real time mode the structural state when impacts occur. The proposed smart impact visualization inspection (IVI) technique mainly consists of five functional modules, which are the signal data preprocessing (SDP), the forward model generator (FMG), the impact positioning calculator (IPC), the inverse model operator (IMO) and structural state estimator (SSE). With regard to the verification of the practicality of the proposed IVI technique, various structure configurations are considered, which are a normal CFRP panel and another CFRP panel with “orange peel” surfaces and a cutout hole. Additionally, since robustness against several background disturbances is also an essential criterion for practical engineering demands, investigations and experimental tests are carried out under random vibration interfering noise (RVIN) conditions. The accuracy of the predictions for unknown impact events on composite structures using the IVI technique is validated under various structure configurations and under changing environmental conditions. The evaluated errors all fall well within a satisfactory limit range. Furthermore, it is concluded that the IVI technique is applicable for impact monitoring, diagnosis and assessment of aerospace composite structures in complex practical engineering environments. PMID:26184196

Invasive Shrub Mapping in an Urban Environment from Hyperspectral and LiDAR-Derived Attributes.

PubMed

Chance, Curtis M; Coops, Nicholas C; Plowright, Andrew A; Tooke, Thoreau R; Christen, Andreas; Aven, Neal

2016-01-01

Proactive management of invasive species in urban areas is critical to restricting their overall distribution. The objective of this work is to determine whether advanced remote sensing technologies can help to detect invasions effectively and efficiently in complex urban ecosystems such as parks. In Surrey, BC, Canada, Himalayan blackberry ( Rubus armeniacus ) and English ivy ( Hedera helix ) are two invasive shrub species that can negatively affect native ecosystems in cities and managed urban parks. Random forest (RF) models were created to detect these two species using a combination of hyperspectral imagery, and light detection and ranging (LiDAR) data. LiDAR-derived predictor variables included irradiance models, canopy structural characteristics, and orographic variables. RF detection accuracy ranged from 77.8 to 87.8% for Himalayan blackberry and 81.9 to 82.1% for English ivy, with open areas classified more accurately than areas under canopy cover. English ivy was predicted to occur across a greater area than Himalayan blackberry both within parks and across the entire city. Both Himalayan blackberry and English ivy were mostly located in clusters according to a Local Moran's I analysis. The occurrence of both species decreased as the distance from roads increased. This study shows the feasibility of producing highly accurate detection maps of plant invasions in urban environments using a fusion of remotely sensed data, as well as the ability to use these products to guide management decisions.

Ethics in human experimentation: the two military physicians who helped develop the Nuremberg Code.

PubMed

Temme, Leonard A

2003-12-01

The Nuremberg Code is generally considered the beginning of modern ethics in human experimentation. The Code is a list of 10 principles that Judge Walter Beals included in the judgment he delivered at the close of the Nuremberg Medical Trial on 19 August 1947. Recently, scholars have studied the origin of the Code, who wrote it, and why. This is important to military medicine and the Aerospace Medical Association in particular because many of the defendants claimed their crimes were experiments in aviation and environmental physiology conducted under wartime conditions. The chief prosecutor of the Nuremberg Medical Trial, General Telford Taylor, relied on the guidance of an advisor provided by the American Medical Association, Andrew C. Ivy, one of the foremost physiologists of his time. The neurologist, Leo Alexander, then a colonel in the U.S. Army Reserves, was another medical advisor. Both men were crucial to the development of Taylor's courtroom strategy. The material Alexander and Ivy provided was incorporated verbatim in the section of the judgment that became the Code. Although both men contributed to the Code, Ivy provided what seems to be the first formulation of many of these principles during a meeting of Allied medical investigators at the Pasteur Institute in July 1946. Naval researchers should note that Ivy had been the Director of the Research Division of the Naval Medical Research Institute when it was commissioned on October 27, 1942.

Poison ivy - oak - sumac rash

MedlinePlus

... reaction can vary from mild to severe. In rare cases, the person with the rash needs to be treated in the hospital. The worst symptoms are often seen during days 4 to 7 after coming in contact with the plant. The rash may last for 1 to 3 ...

Poison Ivy, Oak, and Sumac

MedlinePlus

... on your skin, it causes a blistering skin rash. The rash can range from mild to severe, depending on ... respiratory system. The best way to avoid the rash is to learn what the plants look like ...

Poison Ivy, Oak, and Sumac

MedlinePlus

... Us Media contacts Advertising contacts AAD logo Advertising, marketing and sponsorships Legal notice Copyright © 2018 American Academy ... prohibited without prior written permission. AAD logo Advertising, marketing and sponsorships Legal notice Copyright © 2017 American Academy ...

Status of biological control projects on yellow starthistle, Russian thistle, Scotch thistle, Cape-ivy and French broom

USDA-ARS?s Scientific Manuscript database

The USDA-ARS quarantine laboratory in Albany, CA, in cooperation with foreign scientists, is currently developing classical biological control agents for five species of invasive alien terrestrial weeds. Host specificity testing of the yellow starthistle rosette weevil, Ceratapion basicorne, indica...

Pharmacokinetics of hederacoside C, an active ingredient in AG NPP709, in rats.

PubMed

Kim, Ju Myung; Yoon, Ji Na; Jung, Ji Won; Choi, Hye Duck; Shin, Young June; Han, Chang Kyun; Lee, Hye Suk; Kang, Hee Eun

2013-11-01

1. Hederacoside C (HDC) is one of the active ingredients in Hedera helix leaf extract (Ivy Ex.) and AG NPP709, a new botanical drug to treat acute respiratory infection and chronic inflammatory bronchitis. However, information regarding its pharmacokinetic properties remains limited. 2. Here, we report the pharmacokinetics of HDC in rats after intravenous administration of HDC (3, 12.5, and 25 mg/kg) and after oral administration of HDC, Ivy Ex., and AG NPP709 (equivalent to 12.5, 25, and 50 mg/kg HDC). 3. Linear pharmacokinetics of HDC were identified upon its intravenous administration at doses of 3-25 mg/kg. Intravenous administration of HDC results in relatively slow clearance (1.46-2.08 mL/min/kg) and a small volume of distribution at steady state (138-222 mL/kg), while oral administration results in a low absolute oral bioavailability (F) of 0.118-0.250%. The extremely low F of HDC may be due to poor absorption of HDC from the gastrointestinal (GI) tract and/or its decomposition therein. 4. The oral pharmacokinetics of HDC did not differ significantly among pure HDC, Ivy Ex., and AG NPP709.

Are ecologically important tree species the most useful? A case study from indigenous people in the Bolivian Amazon.

PubMed

Guèze, Maximilien; Luz, Ana Catarina; Paneque-Gálvez, Jaime; Macía, Manuel J; Orta-Martínez, Martí; Pino, Joan; Reyes-García, Victoria

2014-03-01

Researchers have argued that indigenous peoples preferably use the most apparent plant species, particularly for medicinal uses. However, the association between the ecological importance of a species and its usefulness remains unclear. In this paper we quantify such association for six use categories (firewood, construction, materials, food, medicines and other uses). We collected data on the uses of 58 tree species, as reported by 93 informants in 22 villages in the Tsimane' territory (Bolivian Amazon). We calculated the ecological importance of the same species by deriving their importance value index (IVI) in 48 0.1-ha old-growth forest plots. Matching both data sets, we found a positive relation between the IVI of a species and its overall use value (UV) as well as with its UV for construction and materials. We found a negative relation between IVI and UV for species that were reportedly used for medicine and food uses, and no clear pattern for the other categories. We hypothesize that species used for construction or crafting purposes because of their physical properties are more easily substitutable than species used for medicinal or edible purposes because of their chemical properties.

Are ecologically important tree species the most useful? A case study from indigenous people in the Bolivian Amazon

PubMed Central

Guèze, Maximilien; Luz, Ana Catarina; Paneque-Gálvez, Jaime; Macía, Manuel J.; Orta-Martínez, Martí; Pino, Joan; Reyes-García, Victoria

2015-01-01

Researchers have argued that indigenous peoples preferably use the most apparent plant species, particularly for medicinal uses. However, the association between the ecological importance of a species and its usefulness remains unclear. In this paper we quantify such association for six use categories (firewood, construction, materials, food, medicines and other uses). We collected data on the uses of 58 tree species, as reported by 93 informants in 22 villages in the Tsimane’ territory (Bolivian Amazon). We calculated the ecological importance of the same species by deriving their importance value index (IVI) in 48 0.1-ha old-growth forest plots. Matching both data sets, we found a positive relation between the IVI of a species and its overall use value (UV) as well as with its UV for construction and materials. We found a negative relation between IVI and UV for species that were reportedly used for medicine and food uses, and no clear pattern for the other categories. We hypothesize that species used for construction or crafting purposes because of their physical properties are more easily substitutable than species used for medicinal or edible purposes because of their chemical properties. PMID:26097243

Comparative cyto-histological study of needle tip aspirates and entry sites after intravitreal injection using different needle types

PubMed Central

Lytvynchuk, Lyubomyr; Sergienko, Andrij; Savytska, Iryna; Albert, Réka; Glittenberg, Carl; Binder, Susanne; Petrovski, Goran

2017-01-01

A comparison of the cellular content of needle tip aspirates and entry sites after transconjunctival intravitreal injection (IVI) using different needle types was performed. White outbred rats and human cadaver eyes were used for IVI by hypodermic 27 gauge (G) and 30G needles, and spinal anesthesia Pencan 27G needles. Aspiration of vitreous for quantitative morphological and cell cultivation analysis, as well as cyto-histological analysis of aspirates and entry sites were carried out. The most common cells in the aspirates from all needle types were conjunctival epithelial-, ciliary body non-pigmented epithelial- and sclerocyte-like cells and granular proteins. Crystallized vitreous specimens were present in each aspirate. The entry sites of hypodermic needles showed marked trauma in all wall layers of rat and human eyes accompanied by cellular destruction and hemorrhages. Pencan 27G needle caused less tissue trauma with partial reposition of sclerocytes. Transconjunctival IVIs with hypodermic 27G and 30G, and Pencan 27G needles result in trauma of all layers of the eyeball. The possible consequences of cellular content being cut and injected into the eye, as well as the entry site wound shape deserve future consideration and improvements. PMID:28692684

One project`s waste is another project`s resource

DOE Office of Scientific and Technical Information (OSTI.GOV)

Short, J.

1997-02-01

The author describes the efforts being made toward pollution prevention within the DOE complex, as a way to reduce overall project costs, in addition to decreasing the amount of waste to be handled. Pollution prevention is a concept which is trying to be ingrained into project planning. Part of the program involves the concept that ultimately the responsibility for waste comes back to the generator. Parts of the program involve efforts to reuse materials and equipment on new projects, to recycle wastes to generate offsetting revenue, and to increase awareness, accountability and incentives so as to stimulate action on thismore » plan. Summaries of examples are presented in tables.« less

Overview of Future of Probabilistic Methods and RMSL Technology and the Probabilistic Methods Education Initiative for the US Army at the SAE G-11 Meeting

NASA Technical Reports Server (NTRS)

Singhal, Surendra N.

2003-01-01

The SAE G-11 RMSL Division and Probabilistic Methods Committee meeting sponsored by the Picatinny Arsenal during March 1-3, 2004 at Westin Morristown, will report progress on projects for probabilistic assessment of Army system and launch an initiative for probabilistic education. The meeting features several Army and industry Senior executives and Ivy League Professor to provide an industry/government/academia forum to review RMSL technology; reliability and probabilistic technology; reliability-based design methods; software reliability; and maintainability standards. With over 100 members including members with national/international standing, the mission of the G-11s Probabilistic Methods Committee is to enable/facilitate rapid deployment of probabilistic technology to enhance the competitiveness of our industries by better, faster, greener, smarter, affordable and reliable product development.

The plant hopper Issus coleoptratus can detoxify phloem sap saponins including the degradation of the terpene core

PubMed Central

Himmelsbach, Markus; Weth, Agnes; Böhme, Christine; Schwarz, Martin; Bräunig, Peter; Baumgartner, Werner

2016-01-01

ABSTRACT Issus coleoptratus is a small plant hopper which mainly feeds on the phloem sap from ivy. Although all parts of ivy are poisonous as the plant contains saponins, especially hederasaponins, I. coleoptratus can cope with the poison. In contrast to other animals like the stick insect Carausius morosus which accumulates saponins in its body, I. coleoptratus can degrade and disintegrate not only the saponins but even the genines, i.e. the triterpene core of the substances. This is perhaps made possible by a specialised midgut and/or the salivary glands. When the glands and the gut are dissected and added to saponins in solution, the saponins, including the genines, are degraded ex vivo. PMID:26863940

OBLIQUE VIEW, REAR ELEVATION, LOOKING NORTHEAST Mountain Home Air ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

OBLIQUE VIEW, REAR ELEVATION, LOOKING NORTHEAST - Mountain Home Air Force Base 1958 Senior Officers' Housing, General's Residence, Rabeni Street (originally Ivy Street), Mountain Home, Elmore County, ID

Use of prescribed burning for managing natural and historic resources in Chickamauga and Chattanooga National Military Park, USA

NASA Astrophysics Data System (ADS)

Faulkner, Jerry L.; Clebsch, Edward E. C.; Sanders, William L.

1989-09-01

The purpose of this study was to provide the National Park Service with quantitative information regarding the effect of fire on fuel loads and pest species such as Lonicera japonica, Ligustrum sinense, and Rhus radicans. Three study areas of ten plots each were located in Chickamauga Battlefield Reservation of the Chickamauga and Chattanooga National Military Park. Fuel weights, aboveground biomass of honeysuckle, and counts of privet and poison ivy were collected both before and after prescribed fire. Additionally, one fourth of each of 14 plots was treated with glyphosate (tradename Roundup) to test for the use of fire as a herbicide pretreatment. This was a randomized block design with subsampling. Prescribed burning did significantly (α = 0.05) reduce fuel loads and the biomass of honeysuckle on burned plots. There was a statistically different response in fuel load reduction between fall and winter burns. Poison ivy significantly increased on burned plots, while privet counts did not vary significantly. Applications of glyphosate negatively impacted all three target species. Honeysuckle appeared to be damaged more readily on untreated plots, while no difference in response was noted on privet. Significantly more poison ivy growing points were killed by herbicide applications on burned plots than on unburned plots.

Project management of life-science research projects: project characteristics, challenges and training needs.

PubMed

Beukers, Margot W

2011-02-01

Thirty-four project managers of life-science research projects were interviewed to investigate the characteristics of their projects, the challenges they faced and their training requirements. A set of ten discriminating parameters were identified based on four project categories: contract research, development, discovery and call-based projects--projects set up to address research questions defined in a call for proposals. The major challenges these project managers are faced with relate to project members, leadership without authority and a lack of commitment from the respective organization. Two-thirds of the project managers indicated that they would be interested in receiving additional training, mostly on people-oriented, soft skills. The training programs that are currently on offer, however, do not meet their needs. Copyright © 2010 Elsevier Ltd. All rights reserved.

Determination of Surface Charge of Titanium Dioxide (Anatase) at High Ionic Strength

NASA Astrophysics Data System (ADS)

Schoonen, M. A.; Strongin, D. R.

2014-12-01

Charge development on mineral surfaces is an important control on the fate of minor and trace elements in a wide range of environments, including in possible radioactive waste repositories. Formation waters have often a high ionic strength. In this study, we determined the zeta potential (ζ) of anatase in potassium chloride solutions with concentrations up to 3M (25°C). The zeta potential is the potential at the hydrodynamic shear plane. In this study, we made use of the electro-acoustic effect. This effect is based on the development of a measureable potential/current when the electrical double layer outside the shearplane is separated from a charged particle through rapid oscillation induced by a sound wave. The advantage of this type of measurement is that the particles are not subjected to a high electric field (common to typical zeta potential measurements), which leads to electrode reactions and a shift of solution pH. Measurements were collected by subtracting the ion vibration current (IVI) due to the presence of potassium and chloride ions from the CVI. The correction is necessary for measurements in solutions with I > 0.25 M. This subtraction was done at each of the measurement conditions by centrifuging the slurrly, measuring the IVI of the supernatant, reconstituting the slurry, and then measuring CVI of the slurry. Subtraction of IVI at each condition is critical because IVI changes with pH and accounts for most of raw signal. The results show that the anatase isoelectric point shifts from a pH ~6.5 to a value of ~4.5 at 1M KCl. At ionic strength in excess of 1 M KCl, the surface appears to be slightly negatively charged accross the pH range accessible by this technique (pH 2.5-10). The loss of an isoelectric point suggests that KCl is no longer an indifferent electrolyte at 1 M KCl and higher. The results are in disagreement with earlier measurements in which anatase was shown to have a positive charge at high ionic strength across the pH scale. The

OBLIQUE VIEW, REAR ELEVATION, LOOKING SOUTHSOUTHWEST Mountain Home Air ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

OBLIQUE VIEW, REAR ELEVATION, LOOKING SOUTH-SOUTHWEST - Mountain Home Air Force Base 1958 Senior Officers' Housing, General's Residence, Rabeni Street (originally Ivy Street), Mountain Home, Elmore County, ID

OBLIQUE VIEW, FRONT ELEVATION, LOOKING WESTSOUTHWEST Mountain Home Air ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

OBLIQUE VIEW, FRONT ELEVATION, LOOKING WEST-SOUTHWEST - Mountain Home Air Force Base 1958 Senior Officers' Housing, General's Residence, Rabeni Street (originally Ivy Street), Mountain Home, Elmore County, ID

The Agenda-Setting of Ivy Lee.

ERIC Educational Resources Information Center

Olasky, Marvin N.

Journalism historians in recent years have made good use of agenda-setting theory in research, but there has been one drawback: in concentrating on the political and economic views of publishers, editors, and reporters, the agendas of those working behind the scenes, the public relations men and women have been overlooked. The public relations…

Poison in the Halls of Ivy.

ERIC Educational Resources Information Center

Zirkel, Perry A.

1997-01-01

Discusses a California case involving a tenured professor's controversial teaching style, which focused on "obscene" topics and assignments that allegedly humiliated female students. The professor eventually prevailed in a Ninth Circuit appeal. The lesson: when attempting to eradicate sexual harassment, we cannot abandon important First…

Integrated corridor management initiative : demonstration phase evaluation, San Diego traveler response analysis test plan.

DOT National Transportation Integrated Search

1995-10-01

REAL-TIME TRAFFIC INFORMATION, ROUTE GUIDANCE, ROUTE PLANNING, INTELLIGENT VEHICLE INITIATIVE OR IVI ">">KEYWORDS: OPERATIONAL TESTS, TRAVTEK, ADVANCED TRAVELER INFORMATION SYSTEMS OR ATIS, ADVANCED TRAFFIC MANAGEMENT SYSTEMS OR ATMS, INTELLI...

Concentrating Solar Power Projects - Power Tower Projects | Concentrating

Science.gov Websites

(CSP) projects that use power tower systems are listed below-alphabetically by project name. You can browse a project profile by clicking on the project name. You can also find related information on power Aurora Solar Energy Project Copiapó Crescent Dunes Solar Energy Project (Tonopah) Dahan Power Plant DEWA

Ace Project as a Project Management Tool

ERIC Educational Resources Information Center

Cline, Melinda; Guynes, Carl S.; Simard, Karine

2010-01-01

The primary challenge of project management is to achieve the project goals and objectives while adhering to project constraints--usually scope, quality, time and budget. The secondary challenge is to optimize the allocation and integration of resources necessary to meet pre-defined objectives. Project management software provides an active…

Project Success in Agile Development Software Projects

ERIC Educational Resources Information Center

Farlik, John T.

2016-01-01

Project success has multiple definitions in the scholarly literature. Research has shown that some scholars and practitioners define project success as the completion of a project within schedule and within budget. Others consider a successful project as one in which the customer is satisfied with the product. This quantitative study was conducted…

An IS Project Management Course Project

ERIC Educational Resources Information Center

Frank, Ronald L.

2010-01-01

Information Systems curricula should provide project management (PM) theory, current practice, and hands-on experience. The schedule usually does not allow time in Analysis and Design courses for development oriented project management instruction other than a short introduction. Similarly, networking courses usually don't put project management…

Project Panama: An International Service Project

ERIC Educational Resources Information Center

Aydlett, Lydia; Randolph, Mickey; Wells, Gayle

2010-01-01

Participation in service learning projects is a growing phenomenon at universities and colleges. Research indicates service projects are beneficial for college students and adults. There is little data investigating developmental differences in how younger versus older participants perceive the service learning process. In this project, older…

Concentrating Solar Power Projects - Godawari Solar Project | Concentrating

Science.gov Websites

Solar Power | NREL Godawari Solar Project This page provides information on Godawari Solar Project, a concentrating solar power (CSP) project, with data organized by background, participants, and power plant configuration. Status Date: February 13, 2014 Project Overview Project Name: Godawari Solar

Quality Assurance Project Plan for Citizen Science Projects

EPA Pesticide Factsheets

The Quality Assurance Project Plan is necessary for every project that collects or uses environmental data. It documents the project planning process and serves as a blueprint for how your project will run.

Development Of Performance Specifications For Collision Avoidance Systems For Lane Change, Merging, And Backing, Task 3 - Interim Report: Test Of Existing Hardware

DOT National Transportation Integrated Search

1995-05-01

KEYWORDS : ADVANCED VEHICLE CONTROL & SAFETY SYSTEMS OR AVCSS, COLLISION WARNING/AVOIDANCE SYSTEMS, CRASH REDUCTION, INTELLIGENT VEHICLE INITIATIVE OR IVI : RESULTS FROM THE TESTING OF ELEVEN COLLISION AVOIDANCE SYSTEMS (CAS) FOR LANE CHANGE, ...

Projective-anticipating, projective, and projective-lag synchronization of time-delayed chaotic systems on random networks.

PubMed

Feng, Cun-Fang; Xu, Xin-Jian; Wang, Sheng-Jun; Wang, Ying-Hai

2008-06-01

We study projective-anticipating, projective, and projective-lag synchronization of time-delayed chaotic systems on random networks. We relax some limitations of previous work, where projective-anticipating and projective-lag synchronization can be achieved only on two coupled chaotic systems. In this paper, we realize projective-anticipating and projective-lag synchronization on complex dynamical networks composed of a large number of interconnected components. At the same time, although previous work studied projective synchronization on complex dynamical networks, the dynamics of the nodes are coupled partially linear chaotic systems. In this paper, the dynamics of the nodes of the complex networks are time-delayed chaotic systems without the limitation of the partial linearity. Based on the Lyapunov stability theory, we suggest a generic method to achieve the projective-anticipating, projective, and projective-lag synchronization of time-delayed chaotic systems on random dynamical networks, and we find both its existence and sufficient stability conditions. The validity of the proposed method is demonstrated and verified by examining specific examples using Ikeda and Mackey-Glass systems on Erdos-Renyi networks.

Study for online range monitoring with the interaction vertex imaging method.

PubMed

Finck, Ch; Karakaya, Y; Reithinger, V; Rescigno, R; Baudot, J; Constanzo, J; Juliani, D; Krimmer, J; Rinaldi, I; Rousseau, M; Testa, E; Vanstalle, M; Ray, C

2017-11-21

Ion beam therapy enables a highly accurate dose conformation delivery to the tumor due to the finite range of charged ions in matter (i.e. Bragg peak (BP)). Consequently, the dose profile is very sensitive to patients anatomical changes as well as minor mispositioning, and so it requires improved dose control techniques. Proton interaction vertex imaging (IVI) could offer an online range control in carbon ion therapy. In this paper, a statistical method was used to study the sensitivity of the IVI technique on experimental data obtained from the Heidelberg Ion-Beam Therapy Center. The vertices of secondary protons were reconstructed with pixelized silicon detectors. The statistical study used the [Formula: see text] test of the reconstructed vertex distributions for a given displacement of the BP position as a function of the impinging carbon ions. Different phantom configurations were used with or without bone equivalent tissue and air inserts. The inflection points in the fall-off region of the longitudinal vertex distribution were computed using different methods, while the relation with the BP position was established. In the present setup, the resolution of the BP position was about 4-5 mm in the homogeneous phantom under clinical conditions (10 6 incident carbon ions). Our results show that the IVI method could therefore monitor the BP position with a promising resolution in clinical conditions.

Study for online range monitoring with the interaction vertex imaging method

NASA Astrophysics Data System (ADS)

Finck, Ch; Karakaya, Y.; Reithinger, V.; Rescigno, R.; Baudot, J.; Constanzo, J.; Juliani, D.; Krimmer, J.; Rinaldi, I.; Rousseau, M.; Testa, E.; Vanstalle, M.; Ray, C.

2017-12-01

Ion beam therapy enables a highly accurate dose conformation delivery to the tumor due to the finite range of charged ions in matter (i.e. Bragg peak (BP)). Consequently, the dose profile is very sensitive to patients anatomical changes as well as minor mispositioning, and so it requires improved dose control techniques. Proton interaction vertex imaging (IVI) could offer an online range control in carbon ion therapy. In this paper, a statistical method was used to study the sensitivity of the IVI technique on experimental data obtained from the Heidelberg Ion-Beam Therapy Center. The vertices of secondary protons were reconstructed with pixelized silicon detectors. The statistical study used the χ2 test of the reconstructed vertex distributions for a given displacement of the BP position as a function of the impinging carbon ions. Different phantom configurations were used with or without bone equivalent tissue and air inserts. The inflection points in the fall-off region of the longitudinal vertex distribution were computed using different methods, while the relation with the BP position was established. In the present setup, the resolution of the BP position was about 4-5 mm in the homogeneous phantom under clinical conditions (106 incident carbon ions). Our results show that the IVI method could therefore monitor the BP position with a promising resolution in clinical conditions.

Project-Based Teaching: Helping Students Make Project Connections

NASA Astrophysics Data System (ADS)

Johnson, Heather Jo Pusich

Project-based curriculum materials are designed to support students in engaging with scientific content and practices in meaningful ways, with the goal of improving students' science learning. However, students need to understand the connections between what they are doing on a day-to-day basis with respect to the goals of the overall project for students to get the motivational and cognitive benefits of a project-based approach. In this dissertation, I looked at the challenges that four ninth grade science teachers faced as they helped students to make these connections using a project-based environmental science curriculum. The analysis revealed that in general when the curriculum materials made connections explicit, teachers were better able to articulate the relationship between the lesson and the project during enactment. However, whether the connections were explicit or implicit in the materials, enactments of the same lesson across teachers revealed that teachers leveraged different aspects of the project context in different ways depending on their knowledge, beliefs, and goals about project-based teaching. The quantitative analysis of student data indicated that when teacher enactments supported project goals explicitly, students made stronger connections between a lesson and the project goal. Therefore, a teacher's ability to make clear connections during classroom instruction is essential. Furthermore, when students made connections between each lesson and the larger project goals their attitudes toward the lesson were more positive and they performed better on the final assessment. These findings suggest that connections between individual lessons and the goals of the project are critical to the effectiveness of project-based learning. This study highlights that while some teachers were able to forge these connections successfully as a result of leveraging cognitive resources, teachers' beliefs, knowledge and goals about project-based teaching are

Poison plants (image)

MedlinePlus

... by poor circulation, even stress. An example of contact dermatitis is the reaction of a sensitive person's skin to poison ivy, oak or sumac. Contact with these plants, which contain a chemical called ...

SAE J2735 standard : applying the systems engineering process.

DOT National Transportation Integrated Search

1998-11-01

As part of the U.S. Department of Transportations Intelligent Vehicle Initiative (IVI) program, the Federal Highway Administration investigated the human factors research needs for integrating in-vehicle safety and driver information technologies ...

20 CFR 654.404 - Housing site.

Code of Federal Regulations, 2014 CFR

2014-04-01

... similar hazards. (c) Grounds within the housing site shall be free from debris, noxious plants (poison ivy, etc.) and uncontrolled weeds or brush. (d) The housing site shall provide a space for recreation...

20 CFR 654.404 - Housing site.

Code of Federal Regulations, 2013 CFR

2013-04-01

... similar hazards. (c) Grounds within the housing site shall be free from debris, noxious plants (poison ivy, etc.) and uncontrolled weeds or brush. (d) The housing site shall provide a space for recreation...

20 CFR 654.404 - Housing site.

Code of Federal Regulations, 2011 CFR

2011-04-01

... similar hazards. (c) Grounds within the housing site shall be free from debris, noxious plants (poison ivy, etc.) and uncontrolled weeds or brush. (d) The housing site shall provide a space for recreation...

20 CFR 654.404 - Housing site.

Code of Federal Regulations, 2012 CFR

2012-04-01

... similar hazards. (c) Grounds within the housing site shall be free from debris, noxious plants (poison ivy, etc.) and uncontrolled weeds or brush. (d) The housing site shall provide a space for recreation...

20 CFR 654.404 - Housing site.

Code of Federal Regulations, 2010 CFR

2010-04-01

... similar hazards. (c) Grounds within the housing site shall be free from debris, noxious plants (poison ivy, etc.) and uncontrolled weeds or brush. (d) The housing site shall provide a space for recreation...

Integrated ITS Capabilities In Transit Vehicles: Human Factors Research Needs

DOT National Transportation Integrated Search

1998-11-01

As part of the U.S. Department of Transportation's Intelligent Vehicle Initiative (IVI) program, the Federal Highway Administration (FHWA) investigated human factors research needs for integrating in-vehicle safety and driver information technologies...

Variable Dynamic Testbed Vehicle Dynamics Analysis

DOT National Transportation Integrated Search

1996-03-01

ANTI-ROLL BAR, EMULATION, FOUR-WHEEL-STEERING, LATERAL RESPONSE CHARACTERISTICS, SIMULATION, VARIABLE DYNAMIC TESTBED VEHICLE, INTELLIGENT VEHICLE INITIATIVE OR IVI : THE VARIABLE DYNAMIC TESTBED VEHICLE (VDTV) CONCEPT HAS BEEN PROPOSED AS A TOOL...

Integrated ITS capabilities in transit vehicles : human factors research needs

DOT National Transportation Integrated Search

1998-11-01

As part of the U.S. Department of Transportation's Intelligent Vehicle Initiative (IVI) program, the Federal Highway Administration (FHWA) investigated human factors research needs for integrating in-vehicle safety and driver information technologies...

Concentrating Solar Power Projects - Parabolic Trough Projects |

Science.gov Websites

Project Godawari Solar Project Gujarat Solar One Gulang 100MW Thermal Oil Parabolic Trough project Guzmán Kuraymat (ISCC Kuraymat) Kathu Solar Park KaXu Solar One KVK Energy Solar Project La Africana La Dehesa La Power Facility Nevada Solar One (NSO) NOOR I NOOR II Olivenza 1 Orellana Palma del Río I Palma del Río

Efficacy of the saponin component of Impatiens capensis Meerb.in preventing urushiol-induced contact dermatitis.

PubMed

Motz, Vicki A; Bowers, Christopher P; Kneubehl, Alexander R; Lendrum, Elizabeth C; Young, Linda M; Kinder, David H

2015-03-13

Many different tribes of American Indians used jewelweed, Impatiens capensis Meerb, as a plant mash to reduce development of poison ivy dermatitis. Saponins are a natural soapy constituent found within plants. A 2012 study suggested that saponins may be present in jewelweed which could be responsible for its efficacy in preventing rash development following contact with Toxicodendron radicans (L.) Kuntze (poison ivy). This study validated this hypothesis and demonstrated additional biological activity of the jewelweed saponin containing extract. Fresh I. capensis leaves were extracted with methanol and further partitioned between ethyl acetate and water, with a final separation between water and n-butanol, to obtain a saponin containing extract. The presence of saponins in the extract was demonstrated by the observation of foaming and using a vanillin colorimetric assay for total saponins. Efficacy of the saponin containing extracts in rash reduction was tested by brushing poison ivy (PI) onto the forearms of volunteers (N=23) in six locations and treating these PI exposed areas with distilled water (control), saponin containing extracts, fresh plant mashes, and soaps made with and without plant extracts. Saponin containing extracts were further tested for biological activity against both gram negative and gram positive bacteria and against cancer cell lines A-375, HT-29, and MCF-7. Additionally, because saponins have been shown to have a stimulatory effect in cardiac muscle 2 µl saponin extract was applied superficially to black worms, Lumbriculus variegatus (N=5). Both saponin containing extracts and all soaps tested were effective in reducing poison ivy dermatitis; thus, saponin content correlates with PI rash prevention. No apparent antibiosis was observed against any bacteria tested; however, dose response cytotoxicity was documented against MCF-7 breast cancer cells and cytostatic activity was seen against the HT-29 colon cancer cell lines. Lumbriculus

Adapting Project Management Practices to Research-Based Projects

NASA Technical Reports Server (NTRS)

Bahr, P.; Baker, T.; Corbin, B.; Keith, L.; Loerch, L.; Mullenax, C.; Myers, R.; Rhodes, B.; Skytland, N.

2007-01-01

From dealing with the inherent uncertainties in outcomes of scientific research to the lack of applicability of current NASA Procedural Requirements guidance documentation, research-based projects present challenges that require unique application of classical project management techniques. If additionally challenged by the creation of a new program transitioning from basic to applied research in a technical environment often unfamiliar with the cost and schedule constraints addressed by project management practices, such projects can find themselves struggling throughout their life cycles. Finally, supplying deliverables to a prime vehicle customer, also in the formative stage, adds further complexity to the development and management of research-based projects. The Biomedical Research and Countermeasures Projects Branch at NASA Johnson Space Center encompasses several diverse applied research-based or research-enabling projects within the newly-formed Human Research Program. This presentation will provide a brief overview of the organizational structure and environment in which these projects operate and how the projects coordinate to address and manage technical requirements. We will identify several of the challenges (cost, technical, schedule, and personnel) encountered by projects across the Branch, present case reports of actions taken and techniques implemented to deal with these challenges, and then close the session with an open forum discussion of remaining challenges and potential mitigations.

The CHPRC Columbia River Protection Project Quality Assurance Project Plan

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fix, N. J.

Pacific Northwest National Laboratory researchers are working on the CHPRC Columbia River Protection Project (hereafter referred to as the Columbia River Project). This is a follow-on project, funded by CH2M Hill Plateau Remediation Company, LLC (CHPRC), to the Fluor Hanford, Inc. Columbia River Protection Project. The work scope consists of a number of CHPRC funded, related projects that are managed under a master project (project number 55109). All contract releases associated with the Fluor Hanford Columbia River Project (Fluor Hanford, Inc. Contract 27647) and the CHPRC Columbia River Project (Contract 36402) will be collected under this master project. Each projectmore » within the master project is authorized by a CHPRC contract release that contains the project-specific statement of work. This Quality Assurance Project Plan provides the quality assurance requirements and processes that will be followed by the Columbia River Project staff.« less

Operation IVY, Pacific Proving Grounds, November 1952. Project 11.5. Radiobiological Studies at Eniwetok before and after Mike Shot

DTIC Science & Technology

1953-06-01

by Species 4.3.3 Radiochemical Analysis 4.4 Invertebrates 4.4.1 Pretest . 4.4.2 Posttest . 15 16 16 18 19 19 19 19 20 20...with Highest Activity, Pretest 4.7 Frequencies of Invertebrate Ashed-sample Counts by Magnitudes, Pre- anc" Posttest .......... 4.8...JANET) BOGOMBOGO (BELLE) BOGALLUA (ALICE) 0 1 2 3 4 5 - PRETEST STATION • - POSTTEST STATION AOMON (SALLY) BIIJIRI (TILDA) ROJOA (URSULA

Veterinary Immunology Committee Toolkit Workshop 2010: progress and plans.

PubMed

Entrican, Gary; Lunney, Joan K

2012-07-15

The 3rd Veterinary Immunology Committee (VIC) Toolkit Workshop took place at the 9th International Veterinary Immunology Symposium (IVIS) in Tokyo, Japan on 18th August 2010. The Workshop built on previous Toolkit Workshops and covered various aspects of reagent development, commercialization and provision to the veterinary immunology research community. The emphasis was on open communication about current progress and future plans to avoid duplication of effort and to update priorities for reagent development. There were presentations on the major reagent development and networking projects such as the BBSRC/RERAD Immunological Toolbox (2004-2009), US Veterinary Immune Reagent Network (VIRN 2006-2010) that has just received renewal funding for 2010-2014, and EU Network for Animal Diseases Infectiology Research Facilities project (NADIR 2009-2013). There were also presentations and discussions on the use of reagents for assay development, particularly multiplexing, and how these new technologies will underpin basic research developments. Mechanisms for improved information exchange, especially though websites with VIC playing a central role, were identified. Copyright © 2011 Elsevier B.V. All rights reserved.

Impetigo

MedlinePlus

... Development Infections Diseases & Conditions Pregnancy & Baby Nutrition & Fitness Emotions & Behavior School & Family Life First Aid & Safety Doctors & ... scratch your skin because of a bug bite , eczema , or poison ivy , germs may find a way ...

Onycholysis

MedlinePlus

... reaction to "poison Ivy") to nail hardener or adhesives used to attach the nail tips, or simply ... avoid mechanical cleaning under nails. One should not bandage or cover the cut nails. A drying agent ...

Basic Collision Warning and Driver Information Systems: Human Factors Research Needs

DOT National Transportation Integrated Search

1998-11-01

As part of the U.S. Department of Transportation's Intelligent Vehicle Initiative (IVI) program, the Federal Highway Administration (FHWA) investigated the human factors research needs for integrating in-vehicle safety and driver information technolo...

Integrated Capabilities in Heavy Vehicles: Human Factors Research Needs

DOT National Transportation Integrated Search

1998-11-01

As part of the U.S. Department of Transportation's Intelligent Vehicle Initiative (IVI) program, the Federal Highway Administration (FHWA) investigated the human factors research needs for integrating in-vehicle safety and driver information technolo...

Driving Simulator Based Interactive Experiments : Understanding Driver Behavior, Cognition and Technology Uptake under Information and Communication Technologies

DOT National Transportation Integrated Search

2018-01-31

Advanced Traveler Information Systems (ATIS) and in-vehicle information systems (IVIS) are becoming an integral part of the current driving experience. Although information through in-vehicle technologies provides assistance to drivers with diverse t...

Advanced Traveler Information System Capabilities : Human Factors Research Needs

DOT National Transportation Integrated Search

1998-11-01

As part of the U.S. Department of Transportation's Intelligent Vehicle Initiative (IVI) program, the Federal Highway Administration investigated the human factors research needs for integrating in-vehicle safety and driver information technologies in...

Rear-End Crashes: Problem Size Assessment And Statistical Description

DOT National Transportation Integrated Search

1993-05-01

KEYWORDS : RESEARCH AND DEVELOPMENT OR R&D, ADVANCED VEHICLE CONTROL & SAFETY SYSTEMS OR AVCSS, INTELLIGENT VEHICLE INITIATIVE OR IVI : THIS DOCUMENT PRESENTS PROBLEM SIZE ASSESSMENTS AND STATISTICAL CRASH DESCRIPTION FOR REAR-END CRASHES, INC...

Concentrating Solar Power Projects - Genesis Solar Energy Project |

Science.gov Websites

Concentrating Solar Power | NREL Genesis Solar Energy Project This page provides information on the Genesis Solar Energy Project, a concentrating solar power (CSP) project, with data organized by background, participants, and power plant configuration. The Project includes two 125-MW units incorporating

In Vivo Imaging of Influenza Virus Infection in Immunized Mice

PubMed Central

Czakó, Rita; Vogel, Leatrice; Lamirande, Elaine W.; Bock, Kevin W.; Moore, Ian N.; Ellebedy, Ali H.; Ahmed, Rafi

2017-01-01

ABSTRACT Immunization is the cornerstone of seasonal influenza control and represents an important component of pandemic preparedness strategies. Using a bioluminescent reporter virus, we demonstrate the application of noninvasive in vivo imaging system (IVIS) technology to evaluate the preclinical efficacy of candidate vaccines and immunotherapy in a mouse model of influenza. Sequential imaging revealed distinct spatiotemporal kinetics of bioluminescence in groups of mice passively or actively immunized by various strategies that accelerated the clearance of the challenge virus at different rates and by distinct mechanisms. Imaging findings were consistent with conclusions derived from virus titers in the lungs and, notably, were more informative than conventional efficacy endpoints in some cases. Our findings demonstrate the reliability of IVIS as a qualitative approach to support preclinical evaluation of candidate medical countermeasures for influenza in mice. PMID:28559489

Research Project Evaluation-Learnings from the PATHWAYS Project Experience.

PubMed

Galas, Aleksander; Pilat, Aleksandra; Leonardi, Matilde; Tobiasz-Adamczyk, Beata

2018-05-25

Every research project faces challenges regarding how to achieve its goals in a timely and effective manner. The purpose of this paper is to present a project evaluation methodology gathered during the implementation of the Participation to Healthy Workplaces and Inclusive Strategies in the Work Sector (the EU PATHWAYS Project). The PATHWAYS project involved multiple countries and multi-cultural aspects of re/integrating chronically ill patients into labor markets in different countries. This paper describes key project's evaluation issues including: (1) purposes, (2) advisability, (3) tools, (4) implementation, and (5) possible benefits and presents the advantages of a continuous monitoring. Project evaluation tool to assess structure and resources, process, management and communication, achievements, and outcomes. The project used a mixed evaluation approach and included Strengths (S), Weaknesses (W), Opportunities (O), and Threats (SWOT) analysis. A methodology for longitudinal EU projects' evaluation is described. The evaluation process allowed to highlight strengths and weaknesses and highlighted good coordination and communication between project partners as well as some key issues such as: the need for a shared glossary covering areas investigated by the project, problematic issues related to the involvement of stakeholders from outside the project, and issues with timing. Numerical SWOT analysis showed improvement in project performance over time. The proportion of participating project partners in the evaluation varied from 100% to 83.3%. There is a need for the implementation of a structured evaluation process in multidisciplinary projects involving different stakeholders in diverse socio-environmental and political conditions. Based on the PATHWAYS experience, a clear monitoring methodology is suggested as essential in every multidisciplinary research projects.

Project Notes

ERIC Educational Resources Information Center

School Science Review, 1978

1978-01-01

Presents sixteen project notes developed by pupils of Chipping Norton School and Bristol Grammar School, in the United Kingdom. These Projects include eight biology A-level projects and eight Chemistry A-level projects. (HM)

Concentrating Solar Power Projects - eCare Solar Thermal Project |

Science.gov Websites

Concentrating Solar Power | NREL eCare Solar Thermal Project This page provides information on eCare Solar Thermal Project, a concentrating solar power (CSP) project, with data organized by Project Name: eCare Solar Thermal Project Country: Morocco Location: Undefined Owner(s): CNIM (100

Red, Itchy Rash? Get the Skinny on Dermatitis

MedlinePlus

... poison ivy. The stems and leaves of these plants produce a chemical that’s likely to cause allergies. ... even pets—that come into contact with these plants. Mild cases of allergic contact dermatitis usually disappear ...

Investigation Of Alternative Displays For Side Collision Avoidance Systems, Final Report

DOT National Transportation Integrated Search

1996-12-01

DRIVER-VEHICLE INTERFACE OR DVI, HUMAN FACTORS, DRIVER PREFERENCES, INTELLIGENT VEHICLE INITIATIVE OR IVI : SIDE COLLISION AVOIDANCE SYSTEMS (SCAS) ARE DESIGNED TO WARN OF IMPENDING COLLISIONS AND CAN DETECT NOT ONLY ADJACENT VEHICLES BUT VEHICLES...

21 CFR 310.545 - Drug products containing certain active ingredients offered over-the-counter (OTC) for certain uses.

Code of Federal Regulations, 2014 CFR

2014-04-01

... products. Aspirin Chloral hydrate Chlorobutanol Cyclomethycaine sulfate Eugenol Hexylresorcinol... isothiocyanate Aspirin Bismuth sodium tartrate Camphor (exceeding 3 percent) Capsaicin Capsicum Capsicum... oxide (vii) Poison ivy, poison oak, and poison sumac drug products. Alcohol Aspirin Benzethonium...

21 CFR 310.545 - Drug products containing certain active ingredients offered over-the-counter (OTC) for certain uses.

Code of Federal Regulations, 2013 CFR

2013-04-01

... products. Aspirin Chloral hydrate Chlorobutanol Cyclomethycaine sulfate Eugenol Hexylresorcinol... isothiocyanate Aspirin Bismuth sodium tartrate Camphor (exceeding 3 percent) Capsaicin Capsicum Capsicum... oxide (vii) Poison ivy, poison oak, and poison sumac drug products. Alcohol Aspirin Benzethonium...

21 CFR 310.545 - Drug products containing certain active ingredients offered over-the-counter (OTC) for certain uses.

Code of Federal Regulations, 2012 CFR

2012-04-01

... products. Aspirin Chloral hydrate Chlorobutanol Cyclomethycaine sulfate Eugenol Hexylresorcinol... isothiocyanate Aspirin Bismuth sodium tartrate Camphor (exceeding 3 percent) Capsaicin Capsicum Capsicum... oxide (vii) Poison ivy, poison oak, and poison sumac drug products. Alcohol Aspirin Benzethonium...

Managing Projects for Change: Contextualised Project Management

ERIC Educational Resources Information Center

Tynan, Belinda; Adlington, Rachael; Stewart, Cherry; Vale, Deborah; Sims, Rod; Shanahan, Peter

2010-01-01

This paper will detail three projects which focussed on enhancing online learning at a large Australian distance education University within a School of Business, School of Health and School of Education. Each project had special funding and took quite distinctive project management approaches, which reflect the desire to embed innovation and…

Latex Allergy

MedlinePlus

... skin reactions when using latex. They include: Allergic contact dermatitis. This reaction results from the chemical additives used ... hours after exposure, similar to poison ivy. Irritant contact dermatitis. Not an allergy, this skin irritation is caused ...

Skin, Hair, and Nails

MedlinePlus

... as asthma and seasonal, environmental, and food allergies. Contact dermatitis. This occurs when the skin comes into contact ... or sensitive to. The best-known cause of contact dermatitis is poison ivy, but there are many others, ...

An examination of driver performance under reduced visibility conditions when using an in-vehicle signing and information system (ISIS)

DOT National Transportation Integrated Search

1999-12-01

Recent technological innovations and the need for increased safety and congestion reduction on the world's roads have led to the introduction of In-Vehicle Information Systems (IVIS). These systems will provide navigation and advisory information to ...

49 CFR 325.5 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-10-01

... this part, a traffic railing must have at least 35 percent of its vertical height, from the ground... various low, dense-growing plants, such as ivy, myrtle, low weeds, or brush. (4) Traffic railing means any...

49 CFR 325.5 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-10-01

... this part, a traffic railing must have at least 35 percent of its vertical height, from the ground... various low, dense-growing plants, such as ivy, myrtle, low weeds, or brush. (4) Traffic railing means any...

49 CFR 325.5 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-10-01

... this part, a traffic railing must have at least 35 percent of its vertical height, from the ground... various low, dense-growing plants, such as ivy, myrtle, low weeds, or brush. (4) Traffic railing means any...

Protecting Yourself from Poisonous Plants

MedlinePlus

... NIOSH NIOSH Fast Facts: Protecting Yourself from Poisonous Plants Language: English (US) Español (Spanish) Kreyol Haitien (Hatian ... outdoors is at risk of exposure to poisonous plants, such as poison ivy, poison oak, and poison ...

Taking Care of Your Skin

MedlinePlus

... care you need. Solving Skin Problems Bug bites , bee stings, and poison ivy are all common skin ... Notice of Nondiscrimination Visit the Nemours Web site. Note: All information on KidsHealth® is for educational purposes ...

Shop Projects.

ERIC Educational Resources Information Center

Patton, Bob

Vocational agriculture teachers in Oklahoma prepared the shop project drawings which comprise the document. Seventy-one projects, with lists of required materials, diagrams, and measurements, are included. Construction projects fall into six categories (number of projects in parentheses): Trailers (5), racks (3), livestock production projects…

Environmental Science: 49 Science Fair Projects. Science Fair Projects Series.

ERIC Educational Resources Information Center

Bonnet, Robert L.; Keen, G. Daniel

This book contains 49 science fair projects designed for 6th to 9th grade students. Projects are organized by the topics of soil, ecology (projects in habitat and life cycles), pests and controls (projects in weeds and insects), recycling (projects in resources and conservation), waste products (projects in decomposition), microscopic organisms,…

Project Communication in Functions, Process and Project-Oriented Industiral Companies

NASA Astrophysics Data System (ADS)

Samáková, Jana; Koltnerová, Kristína; Rybanský, Rudolf

2012-12-01

The article is focused on the project communication management. Industrial enterprises, which use project management must constantly search the new ways for improving. One of the possibilities is the change of management from a functional oriented to the projectoriented or process-oriented. Process-oriented and project-oriented companies have better project communication management during the all project life cycle. Communication in the project is a very important factor. According to the arguments of several authors, one of the biggest problem is that threaten the success of the project is just the communication. In each project is an important pillar - and that is communication. Only on the base of communication can the project move forward and achieve the target.

On the reliability of the occlusion technique as a tool for the assessment of the HMI of in-vehicle information and communication systems.

PubMed

Gelau, Christhard; Henning, Matthias J; Krems, Josef F

2009-03-01

In recent years considerable efforts have been spent on the development of the occlusion technique as a procedure for the assessment of the human-machine interface of in-vehicle information and communication systems (IVIS) designed to be used by the driver while driving. The importance and significance of the findings resulting from the application of this procedure depends essentially on its reliability. Because there is a lack of evidence as to whether this basic criterion of measurement is met with this procedure, and because questionable reliability can lead to doubts about their validity, our project strove to clarify this issue. This paper reports on a statistical reanalysis of data obtained from previous experiments. To summarise, the characteristic values found for internal consistency were almost all in the range of .90 for the occlusion technique, which can be considered satisfactory.

The Role Of Driver Inattention In Crashes; New Statistics From The 1995 Crashworthiness Data System

DOT National Transportation Integrated Search

1996-08-08

INTELLIGENT VEHICLE INITIATIVE OR IVI : IN 1995, NHTSA BEGAN EMPLOYING THE CRASHWORTHINESS DATA SYSTEM (CDS) TO OBTAIN MORE IN-DEPTH INFORMATION ON DRIVER INATTENTION-RELATED CRASH CAUSES, INCLUDING DROWSINESS AND MANY FORMS OF DISTRACTION. CDS IS PO...

Run-Off-Road Collision Avoidance Countermeasures Using IVHS Countermeasures, Task 3, Volume 2, Final Report

DOT National Transportation Integrated Search

1995-08-01

INTELLIGENT VEHICLE INITIATIVE OR IVI : THE RUN-OFF-ROAD COLLISION AVOIDANCE USING IVHS COUNTERMEASURES PROGRAM IS TO ADDRESS THE SINGLE VEHICLE CRASH PROBLEM THROUGH APPLICATION OF TECHNOLOGY TO PREVENT AND/OR REDUCE THE SEVERITY OF THESE CRASHES. :...

Releases of Psyttalia fletcheri (Hymenoptera: Braconidae) and sterile flies to suppress melon fly (Diptera: Tephritidae) in Hawaii.

PubMed

Vargas, Roger I; Long, Jay; Miller, Neil W; Delate, Kathleen; Jackson, Charles G; Uchida, Grant K; Bautista, Renato C; Harris, Ernie J

2004-10-01

Ivy gourd, Coccinia grandis (L.) Voigt, patches throughout Kailua-Kona, Hawaii Island, HI, were identified as persistent sources of melon fly, Bactrocera cucurbitae (Coquillett). These patches had a low incidence of Psyttalia fletcheri (Silvestri), its major braconid parasitoid natural enemy in Hawaii, and were used to evaluate augmentative releases of P. fletcheri against melon fly. In field cage studies of releases, numbers of melon flies emerging from ivy gourd fruit placed inside treatment cages were reduced up to 21-fold, and numbers of parasitoids were increased 11-fold. In open field releases of P. fletcheri into ivy gourd patches, parasitization rates were increased 4.7 times in release plots compared with those in control plots. However, there was no significant reduction in emergence of melon flies from fruit. In subsequent cage tests with sterile melon flies and P. fletcheri, combinations of sterile flies and P. fletcheri produced the greatest reduction (9-fold) in melon fly emergence from zucchini, Cucurbita pepo L. Reductions obtained with sterile flies alone or in combination with parasitoids were significantly greater than those in the control, whereas those for parasitoids alone were not. Although these results suggest that the effects of sterile flies were greater than those for parasitoids, from a multitactic melon fly management strategy, sterile flies would complement the effects of P. fletcheri. Cost and sustainability of these nonchemical approaches will be examined further in an ongoing areawide pest management program for melon fly in Hawaii.

Driver memory retention of in-vehicle information system messages

DOT National Transportation Integrated Search

1997-01-01

Memory retention of drivers was tested for traffic- and traveler-related messages displayed on an in-vehicle information system (IVIS). Three research questions were asked: (a) How does in-vehicle visual message format affect comprehension? (b) How d...

Draft version 1.0 final report : evaluation methods and lessons learned from the Minnesota Department of Transportation intelligent vehicle initiative field operational test

DOT National Transportation Integrated Search

2003-09-26

This report on the Evaluation Methods and Lessons Learned for the Mn/DOT Intelligent Vehicle Initiative (IVI) Field Operational Test (FOT) documents the goals and objectives, research approach, methods, and findings of a program to measure the feasib...

Factors in Decisions to Make, Purchase, and Use On-board Safety Technologies

DOT National Transportation Integrated Search

2005-12-01

In support of its goal to reduce large truck-related fatalities and crashes, FMCSA plans to facilitate the deployment of Intelligent Vehicle Initiative (IVI) technologies that have shown a potential to improve the safety of commercial vehicle operati...

Intelligent Vehicle Initiative : needs assessment

DOT National Transportation Integrated Search

1999-11-01

The aim of the Intelligent Vehicle Initiative (IVI) is to accelerate the development and availability of advanced safety and information systems for a variety of vehicle types. Public transit, through the Federal Transit Administration (FTA), is an a...

Asymmetrical social mach bands: exaggeration of social identities on the more esteemed side of group borders.

PubMed

Rozin, Paul; Scott, Sydney E; Zickgraf, Hana F; Ahn, Flora; Jiang, Hong

2014-10-01

Perceptual processes generally enhance borders, because of their high information value. Mach bands are an example in vision. In the social world, borders are also of special significance; one side of a border is generally more esteemed or valued than the other. We claim that entities (individuals, groups) that are just over the border on the positive side tend to exaggerate their membership on the positive side (asymmetrical social Mach bands). We demonstrate this by showing that (a) master's-degree universities use the word university to describe themselves more than major graduate universities do, (b) small international airports use the word international to describe themselves more than major airports do, and (c) University of Pennsylvania students, who are affiliated with a "marginal" Ivy League school, use the word Ivy to describe their school more than Harvard students do. © The Author(s) 2014.

36 CFR 64.9 - Project costs (State and local projects).

Code of Federal Regulations, 2013 CFR

2013-07-01

... 36 Parks, Forests, and Public Property 1 2013-07-01 2013-07-01 false Project costs (State and... RIGHTS-OF-WAY § 64.9 Project costs (State and local projects). To be eligible, acquisition and development costs must be incurred after the date of project approval and during the project period. The...

36 CFR 64.9 - Project costs (State and local projects).

Code of Federal Regulations, 2012 CFR

2012-07-01

... 36 Parks, Forests, and Public Property 1 2012-07-01 2012-07-01 false Project costs (State and... RIGHTS-OF-WAY § 64.9 Project costs (State and local projects). To be eligible, acquisition and development costs must be incurred after the date of project approval and during the project period. The...

36 CFR 64.9 - Project costs (State and local projects).

Code of Federal Regulations, 2014 CFR

2014-07-01

... 36 Parks, Forests, and Public Property 1 2014-07-01 2014-07-01 false Project costs (State and... RIGHTS-OF-WAY § 64.9 Project costs (State and local projects). To be eligible, acquisition and development costs must be incurred after the date of project approval and during the project period. The...

36 CFR 64.9 - Project costs (State and local projects).

Code of Federal Regulations, 2011 CFR

2011-07-01

... 36 Parks, Forests, and Public Property 1 2011-07-01 2011-07-01 false Project costs (State and... RIGHTS-OF-WAY § 64.9 Project costs (State and local projects). To be eligible, acquisition and development costs must be incurred after the date of project approval and during the project period. The...

Operation IVY. Joint Task Force 132, 1952

DTIC Science & Technology

1985-09-01

and auxiliary lenses (filters) must have been selected with great care. Knowledge of the light intensities to be experienced is essen- tial in making...pounds. b. !!et’od (1) The theory behind Bhangmeter operation can be described as follows. The light intensity emanated from an atomic bomb explosion...temperature distribution was made by observing the Light signals from selected spots on the outer surface of the steel case. The very early MM1K case

Measuring the Value of an Ivy Degree.

ERIC Educational Resources Information Center

Gose, Ben

2000-01-01

Study examining the earnings of students accepted by elite colleges but who chose to attend less-selective institutions finds that students do not enhance earnings by graduating from colleges with high average Scholastic Assessment Test scores, suggesting that admissions decisions fail to account for intangibles such as students' ambition,…

Ivy League Experience: Increasing Care, Increasing Engagement

ERIC Educational Resources Information Center

Mata, Silvester G., Jr.

2017-01-01

The purpose of this personal narrative is to document initiatives that were designed and implemented to increase engagement and inclusivity for international students. The university campus of focus is a historically elite institution that enrolls one out of five international undergraduate students when compared to domestic peers. Initiatives…

Examination of the relationship between project management critical success factors and project success of oil and gas drilling projects

NASA Astrophysics Data System (ADS)

Alagba, Tonye J.

Oil and gas drilling projects are the primary means by which oil companies recover large volumes of commercially available hydrocarbons from deep reservoirs. These types of projects are complex in nature, involving management of multiple stakeholder interfaces, multidisciplinary personnel, complex contractor relationships, and turbulent environmental and market conditions, necessitating the application of proven project management best practices and critical success factors (CSFs) to achieve success. Although there is some practitioner oriented literature on project management CSFs for drilling projects, none of these is based on empirical evidence, from research. In addition, the literature has reported alarming rates of oil and gas drilling project failure, which is attributable not to technical factors, but to failure of project management. The aim of this quantitative correlational study therefore, was to discover an empirically verified list of project management CSFs, which consistent application leads to successful implementation of oil and gas drilling projects. The study collected survey data online, from a random sample of 127 oil and gas drilling personnel who were members of LinkedIn's online community "Drilling Supervisors, Managers, and Engineers". The results of the study indicated that 10 project management factors are individually related to project success of oil and gas drilling projects. These 10 CSFs are namely; Project mission, Top management support, Project schedule/plan, Client consultation, Personnel, Technical tasks, Client acceptance, Monitoring and feedback, Communication, and Troubleshooting. In addition, the study found that the relationships between the 10 CSFs and drilling project success is unaffected by participant and project demographics---role of project personnel, and project location. The significance of these findings are both practical, and theoretical. Practically, application of an empirically verified CSFs list to oil

Concentrating Solar Power Projects - eLLO Solar Thermal Project |

Science.gov Websites

Concentrating Solar Power | NREL eLLO Solar Thermal Project This page provides information on Llo Solar Thermal Project, a concentrating solar power (CSP) project, with data organized by Name: eLLO Solar Thermal Project (Llo) Country: France Location: Llo (Pyrénées Orientales) Owner(s

A Correlational Study Assessing the Relationships among Information Technology Project Complexity, Project Complication, and Project Success

ERIC Educational Resources Information Center

Williamson, David J.

2011-01-01

The specific problem addressed in this study was the low success rate of information technology (IT) projects in the U.S. Due to the abstract nature and inherent complexity of software development, IT projects are among the most complex projects encountered. Most existing schools of project management theory are based on the rational systems…

Saving lives through advanced vehicle safety technology : intelligent vehicle initiative

DOT National Transportation Integrated Search

2005-09-01

This final report provides an overview of the intelligent vehicle initiative's (IVI) progress and accomplishments. Authorized in the 1998 Transportation Equity Act for the 21st Century (TEA-21) as part of the U.S. DOT's Intelligent Transportation Sys...

Response, Emergency Staging, Communications, Uniform Management, and Evacuation (R.E.S.C.U.M.E.) : report on functional and performance requirements, and high-level data and communication needs.

DOT National Transportation Integrated Search

1995-06-01

INTELLIGENT VEHICLE INITIATIVE OR IVI ABSTRACT THE GOAL OF THE TRAVTEK CAMERA CAR STUDY WAS TO FURNISH A DETAILED EVALUATION OF DRIVING AND NAVIGATION PERFORMANCE, SYSTEM USABILITY, AND SAFETY FOR THE TRAVTEK SYSTEM. TO ACHIEVE THIS GOAL, AN INSTRUME...

Climate Projections from the NARCliM Project: Bayesian Model Averaging of Maximum Temperature Projections

NASA Astrophysics Data System (ADS)

Olson, R.; Evans, J. P.; Fan, Y.

2015-12-01

NARCliM (NSW/ACT Regional Climate Modelling Project) is a regional climate project for Australia and the surrounding region. It dynamically downscales 4 General Circulation Models (GCMs) using three Regional Climate Models (RCMs) to provide climate projections for the CORDEX-AustralAsia region at 50 km resolution, and for south-east Australia at 10 km resolution. The project differs from previous work in the level of sophistication of model selection. Specifically, the selection process for GCMs included (i) conducting literature review to evaluate model performance, (ii) analysing model independence, and (iii) selecting models that span future temperature and precipitation change space. RCMs for downscaling the GCMs were chosen based on their performance for several precipitation events over South-East Australia, and on model independence.Bayesian Model Averaging (BMA) provides a statistically consistent framework for weighing the models based on their likelihood given the available observations. These weights are used to provide probability distribution functions (pdfs) for model projections. We develop a BMA framework for constructing probabilistic climate projections for spatially-averaged variables from the NARCliM project. The first step in the procedure is smoothing model output in order to exclude the influence of internal climate variability. Our statistical model for model-observations residuals is a homoskedastic iid process. Comparing RCMs with Australian Water Availability Project (AWAP) observations is used to determine model weights through Monte Carlo integration. Posterior pdfs of statistical parameters of model-data residuals are obtained using Markov Chain Monte Carlo. The uncertainty in the properties of the model-data residuals is fully accounted for when constructing the projections. We present the preliminary results of the BMA analysis for yearly maximum temperature for New South Wales state planning regions for the period 2060-2079.

Map projections

USGS Publications Warehouse

,

1993-01-01

A map projection is used to portray all or part of the round Earth on a flat surface. This cannot be done without some distortion. Every projection has its own set of advantages and disadvantages. There is no "best" projection. The mapmaker must select the one best suited to the needs, reducing distortion of the most important features. Mapmakers and mathematicians have devised almost limitless ways to project the image of the globe onto paper. Scientists at the U. S. Geological Survey have designed projections for their specific needs—such as the Space Oblique Mercator, which allows mapping from satellites with little or no distortion. This document gives the key properties, characteristics, and preferred uses of many historically important projections and of those frequently used by mapmakers today.

Projection, introjection, and projective identification: a reformulation.

PubMed

Malancharuvil, Joseph M

2004-12-01

In this essay, the author recommends a reformulation of the psychoanalytic concept of projection. The author proposes that projective processes are not merely defensive maneuvers that interfere with perception, but rather an essential means by which human perception is rendered possible. It is the manner in which human beings test and-evaluate reality in terms of their experiential structure, and their needs for survival and nourishment. Projection is the early phase of introjection.

Project Future Workplace Literacy Project. Final Performance Report.

ERIC Educational Resources Information Center

Jefferson County Public Schools, Louisville, KY.

Project Future was a 3-year project begun in 1994 as a partnership between the Jefferson County Public Schools and Futura Plastics and Engineering, Inc., Louisville, Kentucky. The project targeted the workplace basic skills of plastic injection molding production workers. The skills classes improved the general education of the workers with…

Concentrating Solar Power Projects - Linear Fresnel Reflector Projects |

Science.gov Websites

Kimberlina solar thermal power plant, a linear Fresnel reflector system located near Bakersfield, California Solar Thermal Project eLLO Solar Thermal Project (Llo) IRESEN 1 MWe CSP-ORC pilot project Kimberlina Solar Thermal Power Plant (Kimberlina) Liddell Power Station Puerto Errado 1 Thermosolar Power Plant

Skin Rashes and Other Problems

MedlinePlus

... in that area. Start OverDiagnosisThis could be IRRITANT CONTACT DERMATITIS. It’s caused by a reaction to detergents, perfumes ... other soothing lotions. Start OverDiagnosisThis could be ALLERGIC CONTACT DERMATITIS, caused by POISON IVY, poison oak or poison ...

Veterinary Immunology Committee Toolkit Workshop 2010: Progress and plans

USDA-ARS?s Scientific Manuscript database

The Third Veterinary Immunology Committee (VIC) Toolkit Workshop took place at the Ninth International Veterinary Immunology Symposium (IVIS) in Tokyo, Japan on August 18, 2020. The Workshop built on previous Toolkit Workshops and covered various aspects of reagent development, commercialisation an...

21 CFR 347.50 - Labeling of skin protectant drug products.

Code of Federal Regulations, 2011 CFR

2011-04-01

...: ‘[bullet] rashes’ ‘[bullet] eczema’ ‘[bullet] poison ivy, oak, or sumac’ ‘[bullet] insect bites’].” (5) For... irritation and itching due to: [select one or more of the following: ‘rashes’ or ‘eczema’].” [If both...

21 CFR 347.50 - Labeling of skin protectant drug products.

Code of Federal Regulations, 2012 CFR

2012-04-01

...: ‘[bullet] rashes’ ‘[bullet] eczema’ ‘[bullet] poison ivy, oak, or sumac’ ‘[bullet] insect bites’].” (5) For... irritation and itching due to: [select one or more of the following: ‘rashes’ or ‘eczema’].” [If both...

21 CFR 347.50 - Labeling of skin protectant drug products.

Code of Federal Regulations, 2013 CFR

2013-04-01

...: ‘[bullet] rashes’ ‘[bullet] eczema’ ‘[bullet] poison ivy, oak, or sumac’ ‘[bullet] insect bites’].” (5) For... irritation and itching due to: [select one or more of the following: ‘rashes’ or ‘eczema’].” [If both...

21 CFR 347.50 - Labeling of skin protectant drug products.

Code of Federal Regulations, 2014 CFR

2014-04-01

...: ‘[bullet] rashes’ ‘[bullet] eczema’ ‘[bullet] poison ivy, oak, or sumac’ ‘[bullet] insect bites’].” (5) For... irritation and itching due to: [select one or more of the following: ‘rashes’ or ‘eczema’].” [If both...

STS-133 crew members Lindsey, Boe and Drew during Tool/Repair Kits training with instructor

NASA Image and Video Library

2010-01-26

JSC2010-E-014264 (26 Jan. 2010) --- NASA astronaut Eric Boe, STS-133 pilot, participates in an ISS tools and repair kits training session in the Space Vehicle Mock-up Facility at NASA's Johnson Space Center. Instructor Ivy Apostolakopoulos assisted Boe.

In-Vehicle Information Systems Demand Model (Research Update)

DOT National Transportation Integrated Search

2000-04-01

The goal of in-vehicle information system (IVIS) technologies is to increase the mobility, improve the efficiency, and increase the safety and/or convenience of the motoring public. To achieve this goal, IVISs must be designed to include good human f...

Project Scoping Guidebook for Metropolitan Planning Organization Transportation Projects

DOT National Transportation Integrated Search

2017-08-01

To obtain state and federal funding for proposed transportation projects in metropolitan areas, local governments submit project proposals to their Metropolitan Planning Organization (MPO) during the early stages of project planning. The purpose of t...

Manpower Projection Model Project, Ventura County.

ERIC Educational Resources Information Center

Van Zant, John L.; Lawson, William H.

The final report on Phase 1 of the Manpower Projection Model (MPM) Project provides a guide for implementation of the model system by area Vocational Education Practitioners within any Standard Metropolitan Statistical Area (SMSA). A cooperative effort between Ventura County Superintendent of Schools Office and the Community College District, the…

Watchdog Project

DOE Office of Scientific and Technical Information (OSTI.GOV)

Smith, Rhett; Campbell, Jack; Hadley, Mark

The Watchdog Project completed 100% of the project Statement of Project Objective (SOPO). The Watchdog project was a very aggressive project looking to accomplish commercialization of technology that had never been commercialized, as a result it took six years to complete not the original three that were planned. No additional federal funds were requested from the original proposal and SEL contributed the additional cost share required to complete the project. The result of the Watchdog Project is the world’s first industrial rated Software Defined Network (SDN) switch commercially available. This technology achieved the SOPOO and DOE Roadmap goals to havemore » strong network access control, improve reliability and network performance, and give the asset owner the ability to minimize attack surface before and during an attack. The Watchdog project is an alliance between CenterPoint Energy Houston Electric, Pacific Northwest National Laboratories (PNNL), and Schweitzer Engineering Laboratories, Inc. (SEL). SEL is the world’s leader in microprocessor-based electronic equipment for protecting electric power systems. PNNL performs basic and applied research to deliver energy, environmental, and national security for our nation. CenterPoint Energy is the third largest publicly traded natural gas delivery company in the U.S and third largest combined electricity and natural gas delivery company. The Watchdog Project efforts were combined with the SDN Project efforts to produce the entire SDN system solution for the critical infrastructure. The Watchdog project addresses Topic Area of Interest 5: Secure Communications, for the DEFOA- 0000359 by protecting the control system local area network itself and the communications coming from and going to the electronic devices on the local network. Local area networks usually are not routed and have little or no filtering capabilities. Combine this with the fact control system protocols are designed with inherent trust the

Building Excellence in Project Execution: Integrated Project Management

DTIC Science & Technology

2015-04-30

challenge by adopting and refining the CMMI Model and building the tenets of integrated project management (IPM) into project planning and execution...Systems Center Pacific (SSC Pacific) is addressing this challenge by adopting and refining the CMMI Model, and building the tenets of integrated project...successfully managing stakeholder expectations and meeting requirements. Under the Capability Maturity Model Integration ( CMMI ), IPM is defined as

ART/Ada design project, phase 1: Project plan

NASA Technical Reports Server (NTRS)

Allen, Bradley P.

1988-01-01

The plan and schedule for Phase 1 of the Ada based ESBT Design Research Project is described. The main platform for the project is a DEC Ada compiler on VAX mini-computers and VAXstations running the Virtual Memory System (VMS) operating system. The Ada effort and lines of code are given in tabular form. A chart is given of the entire project life cycle.

Home Healthcare Workers: How to Prevent Latex Allergies

MedlinePlus

... delayed hypersensitivity) This skin reaction looks like the rash from contact with poison ivy and usually shows up 24– ... after using gloves. • Recognize symptoms of latex allergy (rash; hives; flushing; ... Avoid direct contact with latex gloves and other latex-containing products ...

The ninth international veterinary immunology symposium

USDA-ARS?s Scientific Manuscript database

This Introduction to the special issue of Veterinary Immunology and Immunopathology summarizes the Proceedings of the 9th International Veterinary Immunology Symposium (9th IVIS) held August, 2010, in Tokyo, Japan. Over 340 delegates from 30 countries discussed research progress analyzing the immune...

The Leadership Alliance: Twenty Years of Developing a Diverse Research Workforce

ERIC Educational Resources Information Center

Ghee, Medeva; Collins, Deborah; Wilson, Valerie; Pearson, Willie, Jr.

2014-01-01

The Leadership Alliance is a national academic consortium currently comprising 32 academic institutions including Ivy League and major-research and minority-serving institutions, including Historically Black Colleges and Universities (HBCUs). For 2 decades these institutions have worked collaboratively to train, mentor, and support…

A new genus of mimetic longhorned beetle from St. Lucia, Lesser Antilles (Coleoptera: Cerambycidae: Rhinotragini)

USDA-ARS?s Scientific Manuscript database

A species originally described as Fortuneleptura romei Touroult 2011 (Lepturinae) is placed in a new genus, Iyanola Lingafelter & Ivie (Cerambycinae: Rhinotragini). Along with the new genus description, the species is redescribed and additional collection data is recorded. A key to the genera and ...

Invasive Species Guidebook for Department of Defense Installations in the Chesapeake Bay Watershed: Identification, Control, and Restoration

DTIC Science & Technology

2007-11-01

INSTALLATIONS IN THE CHESAPEAKE BAY WATERSHED IDENTIFICATION AND CONTROL METHODS Cogongrass ( Imperata cylindrica ) Description & Biology – A large...Crown vetch Coronilla varia MD, VA 14 Leafy spurge Euphorbia esula VA 15 Ground ivy Glechoma hederacea DC, MD, PA, VA, WV 17 Cogongrass Imperata

Mosquitocidal activity of a naturally occurring isochroman and synthetic analogs from the plant pathogenic fungus, Diaporthe eres against Aedes aegypti ( Diptera: Culicidae)

USDA-ARS?s Scientific Manuscript database

The culture filtrate of a plant pathogenic fungus that infects English ivy (Hegera helix) was investigated for mosquitocidal constituents by bioassay guided isolation. The fungus responsible for pathogenic effects on the plant Hegera helix has been identified as Diaporthe eres by molecular technique...

Project: "Project!"

ERIC Educational Resources Information Center

Grayson, Katherine

2007-01-01

In November 2006, the editors of "Campus Technology" launched their first-ever High-Resolution Projection Study, to find out if the latest in projector technology could really make a significant difference in teaching, learning, and educational innovation on US campuses. The author and her colleagues asked campus educators,…

Competency model for the project managers of technical projects

NASA Astrophysics Data System (ADS)

Duncan, William R.

1992-05-01

Traditional job description techniques were developed to support compensation decisions for hourly wage earners in a manufacturing environment. Their resultant focus on activities performed on the job works well in this environment where the ability to perform the activity adequately is objectively verifiable by testing and observation. Although many organizations have adapted these techniques for salaried employees and service environments, the focus on activities performed has never been satisfactory. For example, stating that a project manager `prepares regular project status reports' tells us little about what to look for in a potential project manager or how to determine if a practicing project manager is ready for additional responsibilities. The concept of a `competency model' has been developed within the last decade to address this shortcoming. Competency models focus on what skills are needed to perform the tasks defined by the job description. For example, a project manager must be able to communicate well both orally and in writing in order to `prepare regular project status reports.'

How Does a Project Manager's Level of Development Influence Conceptualizations of Project Management and the Project Development Environment?

ERIC Educational Resources Information Center

Lynch, Margaret M.

2013-01-01

This study explores the meaning project managers (PMs) make of their project environment, how they lead their teams and have incorporate complexity into their project management approach. The exploration of the PM's developmental level and meaning making offers a different angle on the project management and leadership literature. The study…

The 9th International Veterinary Immunology Symposium.

PubMed

Lunney, Joan K; Kai, Chieko; Inumaru, Shigeki; Onodera, Takashi

2012-07-15

This special issue of Veterinary Immunology and Immunopathology summarizes the Proceedings of the 9th International Veterinary Immunology Symposium (9th IVIS) held August 2010, in Tokyo, Japan. Over 340 delegates from 30 countries discussed research progress analyzing the immune systems of numerous food animals and wildlife, probing basic immunity and the influence of stress, genetics, nutrition, endocrinology and reproduction. Major presentations addressed defense against pathogens and alternative control and prevention strategies including vaccines, adjuvants and novel biotherapeutics. A special Organisation for Economic Co-operation and Development (OECD) Co-operative Research Programme Sponsored Conference on "Vaccination and Diagnosis for Food Safety in Agriculture" highlighted the particular issue of "Immunology in Bovine Paratuberculosis". In April 2010 there was an outbreak of foot-and-mouth disease (FMD) in the southern part of Japan. This stimulated a special 9th IVIS session on FMD, sponsored by the World Organization for Animal Health (OIE) and the Ministry of Agriculture, Forestry and Fisheries (MAFF) of Japan, to discuss improvements of FMD vaccines, their use in FMD control, and risk assessment for decision management. The 9th IVIS was supported by the Veterinary Immunology Committee (VIC) of the International Union of Immunological Societies (IUIS) and included workshops for its MHC and Toolkit Committees. Finally VIC IUIS presented its 2010 Distinguished Service Award to Dr. Kazuya Yamanouchi for "outstanding contributions to the veterinary immunology community" and its 2010 Distinguished Veterinary Immunologist Award to Dr. Douglas F. Antczak for "outstanding research on equine immunology". Published by Elsevier B.V.

Perceptions of Project Representatives Concerning Project Success and Pre-Project Planning Effort

DTIC Science & Technology

1993-12-01

25 Table 2. What are your main reasons for the project’s level of success? ........... 28 Table 3. What , if anything...Table 3a. Other Categories for Table 3 .......................................................... 32 Table 4. What are your main reasons for your...assessment of the level of effort expended on pre-project planning? ............................. ....... .. .......... .. . .. 33 Table 5. What concerning

Highlight removal based on the regional-projection fringe projection method

NASA Astrophysics Data System (ADS)

Qi, Zhaoshuai; Wang, Zhao; Huang, Junhui; Xing, Chao; Gao, Jianmin

2018-04-01

In fringe projection profilometry, highlight usually causes the saturation and blooming in captured fringes and reduces the measurement accuracy. To solve the problem, a regional-projection fringe projection (RP-FP) method is proposed. Regional projection patterns (RP patterns) are projected onto the tested object surface to avoid the saturation and blooming. Then, an image inpainting technique is employed to reconstruct the missing phases in the captured RP patterns and a complete surface of the tested object is obtained. Experiments verified the effectiveness of the proposed method. The method can be widely used in industrial inspections and quality controlling in mechanical and manufacturing industries.

Postharvest fumigation of California table grapes with ozone to control Western black widow spider (Araneae: Theridiidae)

USDA-ARS?s Scientific Manuscript database

Ozone fumigations were evaluated for postharvest control of Western black widow spider (BWS), Latrodectus hesperus (Chamberlin and Ivie), in fresh table grapes destined for export from California USA. Mature adult female black widow spiders were contained in separate gas-permeable cages within a flo...

Woods and Camping Safety for the Whole Family

MedlinePlus

... mouth are effective for allergic reactions or itchy rashes — from contact with poison ivy to mosquito bites to bee ... Staying Safe Around Animals Going Away to Camp Rashes: The Itchy Truth Hey! A Tick Bit Me! ... Us Partners Editorial Policy Permissions Guidelines Privacy Policy & ...

76 FR 72403 - Access to Confidential Business Information by Primus Solutions, Inc.

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-23

...), Office of Pollution Prevention and Toxics, Environmental Protection Agency, 1200 Pennsylvania Ave., NW... Primus of 6303 Ivy Lane, Suite 130, Greenbelt, MD, will assist the Office of Pollution Prevention and... Director, Information Management Division, Office of Pollution Prevention and Toxics. [FR Doc. 2011-30143...

Highlights of the 8th International Veterinary Immunology Symposium

USDA-ARS?s Scientific Manuscript database

Veterinary immunologists have expanded understanding of the immune systems for our companion animals and developed new vaccines and therapeutics. This manuscript summarizes the highlights of the 8th International Veterinary Immunology Symposium (8 th IVIS) held August 15th-19th, 2007, in Ouro Preto,...

76 FR 758 - Disapproval and Promulgation of Air Quality Implementation Plans; Montana; Revisions to the...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-06

... I-VI, codified as ARM 17.8.1601, 17.8.1602, 17.8.1603, 17.8.1604, 17.8.1605, and 17.8.1606....1605, and 17.8.1606 provide, generally, that an owner or operator of an oil and gas well facility for...

Science project

NASA Image and Video Library

2012-08-23

DRIFTER sensor devices were designed by the Applied Science and Technology Project Office as inexpensive tools that can be used for science projects in local schools. The devices transmit information about water temperature and conductivity for use by Gulf Coast researchers. The DRIFTER project began as an effort to help Gulf Coast oyster fishermen dealing with the effects of fresh water intrusion.

Guidelines for Project Management

NASA Technical Reports Server (NTRS)

Ben-Arieh, David

2001-01-01

Project management is an important part of the professional activities at Kennedy Space Center (KSC). Project management is the means by which many of the operations at KSC take shape. Moreover, projects at KSC are implemented in a variety of ways in different organizations. The official guidelines for project management are provided by NASA headquarters and are quite general. The project reported herein deals with developing practical and detailed project management guidelines in support of the project managers. This report summarizes the current project management effort in the Process Management Division and presents a new modeling approach of project management developed by the author. The report also presents the Project Management Guidelines developed during the summer.

Managing a project's legacy: implications for organizations and project management

NASA Technical Reports Server (NTRS)

Cooper, Lynne P.; Hecht, Michael H.; Majchrzak, Ann

2003-01-01

Organizations that rely on projects to implement their products must find effective mechanisms for propagating lessons learned on one project throughout the organization. A broad view of what constitutes a project's 'legacy' is presented that includes not just the design products and leftover parts, but new processes, relationships, technology, skills, planning data, and performance metrics. Based on research evaluating knowledge reuse in innovative contexts, this paper presents an approach to project legacy management that focuses on collecting and using legacy knowledge to promote organizational learning and effective reuse, while addressing factors of post-project responsibility, information obsolescence, and the importance of ancillary contextual information. .

Lessons Learned from Client Projects in an Undergraduate Project Management Course

ERIC Educational Resources Information Center

Pollard, Carol E.

2012-01-01

This work proposes that a subtle combination of three learning methods offering "just in time" project management knowledge, coupled with hands-on project management experience can be particularly effective in producing project management students with employable skills. Students were required to apply formal project management knowledge to gain…

Georgia Deaf-Blind Pilot Project: Project EPIC. Final Report. Optional Pilot Projects for Children with Deaf-Blindness.

ERIC Educational Resources Information Center

Georgia State Dept. of Education, Atlanta.

This final report describes activities and accomplishments of Project EPIC (Effective Partner Interaction in the Community), a 3-year federally supported project in Georgia to facilitate the establishment and implementation of effective educational practices with students having deaf-blindness. The project was designed to expand students' present…

Project HOLD: A Secondary Learning Disability Project.

ERIC Educational Resources Information Center

Snyder, Marjorie Sims

This document discusses Project HOLD, a Title VI-G Child Service Demonstration Center which was established as a cooperative effort between Northeast Louisiana University and the Ouachita Parish School System. The primary purpose of the project is to plan, explore, implement, and refine a program for students in grades 7 through 12 who have been…

GHPsRUS Project

DOE Data Explorer

Battocletti, Liz

2013-07-09

The GHPsRUS Project's full name is "Measuring the Costs and Benefits of Nationwide Geothermal Heat Pump Deployment." The dataset contains employment and installation price data collected by four economic surveys: (1)GHPsRUS Project Manufacturer & OEM Survey, (2) GHPsRUS Project Geothermal Loop Survey, (3) GHPsRUS Project Mechanical Equipment Installation Survey, and (4) GHPsRUS Geothermal Heat Pump Industry Survey

Educational Project Management Instructional System. Module One. Project Management Executive Orientation.

ERIC Educational Resources Information Center

Cummings, C. Peter; Cook, Desmond L.

This module is the first in a self-instructional program designed to train public school personnel in how to manage educational projects. These may include federally funded projects (such as Title I projects), court-ordered programs (such as a desegregation plan), or locally initiated projects (such as a new math program). The purpose of this…

Construction Project Management for RED HORSE Troop Training Projects

DTIC Science & Technology

1989-02-02

estimating, scheduling, and cost control required for project management decision making in RED HORSE construction projects. The expected benefits of...After receiving tentative approval for a project, either the benefiting base engineering section or the appropriate RED HORSE squadron executes the...approved by the benefiting base commander and forwarded to RED HORSE for review. Once the design has started, the benefiting base reports to Headquarters

Traditional Project Management and the Visual Workplace Environment to Improve Project Success

ERIC Educational Resources Information Center

Fichera, Christopher E.

2016-01-01

A majority of large IT projects fail to meet scheduled deadlines, are over budget and do not satisfy the end user. Many projects fail in spite of utilizing traditional project management techniques. Research of project management has not identified the use of a visual workspace as a feature affecting or influencing the success of a project during…

Plants to Avoid

USDA-ARS?s Scientific Manuscript database

Knowledge of poisonous plants is extremely important for home owners, gardeners, farmers, hunters, hikers, and the rest of the general public. Among the most important plants to avoid in the Delta Region are poison ivy, bull nettle, eastern black nightshade, Queen Ann’s lace, jimsonweed, and trumpe...

The Cornell Urban Scholars Program: Cultivating New York City's Next Generation of Civic Leaders

ERIC Educational Resources Information Center

Reardon, Kenneth M.

2005-01-01

This article describes the origins, evolution, and development of a comprehensive civic engagement program designed to encourage Ivy League students to pursue public service careers with nonprofits and municipal government organizations serving New York City's poorest children, families, and neighborhoods. The article offers a detailed description…

Shopping for Jobs: Mall Internship Program Opens Doors for HVAC Students.

ERIC Educational Resources Information Center

Nolot, Terry

1995-01-01

Ivy Tech State College uses River Falls, a shopping mall, as an enormous heating, ventilation, and air conditioning laboratory. Students spend Saturdays working with full-time technicians getting invaluable training and experience. Students see the program as a professional opportunity and a direct route to jobs. (JOW)

The Black Faculty Gap.

ERIC Educational Resources Information Center

Glazer, Nathan

2003-01-01

Reviews Cole and Barber's "Increasing Faculty Diversity: The Occupational Choices of High-Achieving Minority Students," which has aroused controversy because its findings bear directly on the University of Michigan's affirmative action cases. Cole and Barber surveyed minority and white students in Ivy League, elite, and historically…

10 CFR 1800.10 - Purpose and scope.

Code of Federal Regulations, 2010 CFR

2010-01-01

... NORTHEAST INTERSTATE LOW-LEVEL RADIOACTIVE WASTE COMMISSION DECLARATION OF PARTY STATE ELIGIBILITY FOR NORTHEAST INTERSTATE LOW-LEVEL RADIOACTIVE WASTE COMPACT § 1800.10 Purpose and scope. Pursuant to Articles IV.i.(1), (7), (15), and VII.e. of the Northeast Interstate Low-Level Radioactive Waste Compact...

10 CFR 1800.10 - Purpose and scope.

Code of Federal Regulations, 2012 CFR

2012-01-01

... NORTHEAST INTERSTATE LOW-LEVEL RADIOACTIVE WASTE COMMISSION DECLARATION OF PARTY STATE ELIGIBILITY FOR NORTHEAST INTERSTATE LOW-LEVEL RADIOACTIVE WASTE COMPACT § 1800.10 Purpose and scope. Pursuant to Articles IV.i.(1), (7), (15), and VII.e. of the Northeast Interstate Low-Level Radioactive Waste Compact...

A Locality-Based Threading Algorithm for the Configuration-Interaction Method

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shan, Hongzhang; Williams, Samuel; Johnson, Calvin

The Configuration Interaction (CI) method has been widely used to solve the non-relativistic many-body Schrodinger equation. One great challenge to implementing it efficiently on manycore architectures is its immense memory and data movement requirements. To address this issue, within each node, we exploit a hybrid MPI+OpenMP programming model in lieu of the traditional flat MPI programming model. Here in this paper, we develop optimizations that partition the workloads among OpenMP threads based on data locality,-which is essential in ensuring applications with complex data access patterns scale well on manycore architectures. The new algorithm scales to 256 threadson the 64-core Intelmore » Knights Landing (KNL) manycore processor and 24 threads on dual-socket Ivy Bridge (Xeon) nodes. Compared with the original implementation, the performance has been improved by up to 7× on theKnights Landing processor and 3× on the dual-socket Ivy Bridge node.« less

A Locality-Based Threading Algorithm for the Configuration-Interaction Method

DOE PAGES

Shan, Hongzhang; Williams, Samuel; Johnson, Calvin; ...

2017-07-03

The Configuration Interaction (CI) method has been widely used to solve the non-relativistic many-body Schrodinger equation. One great challenge to implementing it efficiently on manycore architectures is its immense memory and data movement requirements. To address this issue, within each node, we exploit a hybrid MPI+OpenMP programming model in lieu of the traditional flat MPI programming model. Here in this paper, we develop optimizations that partition the workloads among OpenMP threads based on data locality,-which is essential in ensuring applications with complex data access patterns scale well on manycore architectures. The new algorithm scales to 256 threadson the 64-core Intelmore » Knights Landing (KNL) manycore processor and 24 threads on dual-socket Ivy Bridge (Xeon) nodes. Compared with the original implementation, the performance has been improved by up to 7× on theKnights Landing processor and 3× on the dual-socket Ivy Bridge node.« less

A current perspective on availability of tools, resources and networks for veterinary immunology.

PubMed

Entrican, Gary; Lunney, Joan K; Rutten, Victor P; Baldwin, Cynthia L

2009-03-15

There are many diseases of fish, livestock and companion animals that impact negatively on animal health, welfare and productivity and for which there are no effective vaccines. The development of new vaccines is reliant on the availability of well-characterised immunological tools and reagents to understand host-pathogen interactions and identify protective immune responses. Veterinary immunology has always lagged behind mouse and human immunology in terms of development and availability of tools and reagents. However, several initiatives are underway to address this. The Veterinary Immunology Committee (VIC) Toolkit was initiated 6 years ago at the sixth International Veterinary Immunology Symposium (IVIS) in Uppsala and in the intervening period there have been several notable developments that have advanced reagent development and information exchange. This review will discuss advances in veterinary reagent development, networks, databases and commercial availability with particular reference to the second VIC Toolkit workshop held at the eighth IVIS in Ouro Preto, Brazil on the 15th of August 2007.

Concentrating Solar Power Projects - Hami 50 MW CSP Project | Concentrating

Science.gov Websites

Solar Power | NREL Hami 50 MW CSP Project Status Date: April 6, 2018 Project Overview Project MW Status: Under construction Do you have more information, corrections, or comments? Background Technology: Power tower Status: Under construction Country: China City: Hami Region: Xinjiang Autonomous

How to Grow Project Scientists: A Systematic Approach to Developing Project Scientists

NASA Technical Reports Server (NTRS)

Kea, Howard

2011-01-01

The Project Manager is one of the key individuals that can determine the success or failure of a project. NASA is fully committed to the training and development of Project Managers across the agency to ensure that highly capable individuals are equipped with the competencies and experience to successfully lead a project. An equally critical position is that of the Project Scientist. The Project Scientist provides the scientific leadership necessary for the scientific success of a project by insuring that the mission meets or exceeds the scientific requirements. Traditionally, NASA Goddard project scientists were appointed and approved by the Center Science Director based on their knowledge, experience, and other qualifications. However the process to obtain the necessary knowledge, skills and abilities was not documented or done in a systematic way. NASA Goddard's current Science Director, Nicholas White saw the need to create a pipeline for developing new projects scientists, and appointed a team to develop a process for training potential project scientists. The team members were Dr. Harley Thronson, Chair, Dr. Howard Kea, Mr. Mark Goldman, DACUM facilitator and the late Dr. Michael VanSteenberg. The DACUM process, an occupational analysis and evaluation system, was used to produce a picture of the project scientist's duties, tasks, knowledge, and skills. The output resulted in a 3-Day introductory course detailing all the required knowledge, skills and abilities a scientist must develop over time to be qualified for selections as a Project Scientist.

Underestimation of Project Costs

NASA Technical Reports Server (NTRS)

Jones, Harry W.

2015-01-01

Large projects almost always exceed their budgets. Estimating cost is difficult and estimated costs are usually too low. Three different reasons are suggested: bad luck, overoptimism, and deliberate underestimation. Project management can usually point to project difficulty and complexity, technical uncertainty, stakeholder conflicts, scope changes, unforeseen events, and other not really unpredictable bad luck. Project planning is usually over-optimistic, so the likelihood and impact of bad luck is systematically underestimated. Project plans reflect optimism and hope for success in a supposedly unique new effort rather than rational expectations based on historical data. Past project problems are claimed to be irrelevant because "This time it's different." Some bad luck is inevitable and reasonable optimism is understandable, but deliberate deception must be condemned. In a competitive environment, project planners and advocates often deliberately underestimate costs to help gain project approval and funding. Project benefits, cost savings, and probability of success are exaggerated and key risks ignored. Project advocates have incentives to distort information and conceal difficulties from project approvers. One naively suggested cure is more openness, honesty, and group adherence to shared overall goals. A more realistic alternative is threatening overrun projects with cancellation. Neither approach seems to solve the problem. A better method to avoid the delusions of over-optimism and the deceptions of biased advocacy is to base the project cost estimate on the actual costs of a large group of similar projects. Over optimism and deception can continue beyond the planning phase and into project execution. Hard milestones based on verified tests and demonstrations can provide a reality check.

Influence of Selected Stakeholders of Construction Investment Projects on the Course of Project

NASA Astrophysics Data System (ADS)

Bizon-Górecka, Jadwiga; Górecki, Jarosław

2017-10-01

The article presents an entity perspective of the construction investment projects. In a course of the project there are stakeholders who have an indirect influence (e.g. decision-makers in the selection of projects) or a direct influence (e.g. members of the project team). An intuitive opinion about a significant influence of project stakeholders on the project’s course encouraged the authors to undertake a research in this area. The article illustrates the initial phases of the construction project life cycle in a perspective of the entities and, in particular, a role of different stakeholders in making decisions that affect a course of the project. An analysis of the structure of the construction project life cycle makes a substantial involvement of various subjects in the initial phases of the project, i.e. in an initial phase and during a creation of the structures. A key point is to underline the factors of decision-making by the participants of the construction process. It was indicated that the stakeholders have a different impact on the course of the project. In large projects, which have many stakeholders, their role in the implementation of the investment project can vary, depending on the life cycle of the project. They can have positive or negative impacts on achieving the project objectives. The paper presents the results of 100 surveys made among participants of the building processes, executors of the construction projects in the Kuyavian-Pomeranian region. The study was conducted in December 2016 and January 2017. It revealed what is the impact of individual stakeholders of the construction projects on the course of the project. A special attention was paid to a complex relationship between objectives of the project and stakeholders’ goals. A great care to the smallest possible number of risks, which may arise from the different objectives of the project and its stakeholders’ goals, should be focused on the augmentation of correlation of

51. Projection room, looking SW. Original Movietone projection equipment intact. ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

51. Projection room, looking SW. Original Movietone projection equipment intact. Old photo label identifying directional view is inaccurate. This image proves the projection room was expanded southward from its original design prior to the theatre's opening (see also photo WA-197-36). - Fox Theater, Seventh Avenue & Olive Way, Seattle, King County, WA

The Inter-Sectoral Impact Model Intercomparison Project (ISI–MIP): Project framework

PubMed Central

Warszawski, Lila; Frieler, Katja; Huber, Veronika; Piontek, Franziska; Serdeczny, Olivia; Schewe, Jacob

2014-01-01

The Inter-Sectoral Impact Model Intercomparison Project offers a framework to compare climate impact projections in different sectors and at different scales. Consistent climate and socio-economic input data provide the basis for a cross-sectoral integration of impact projections. The project is designed to enable quantitative synthesis of climate change impacts at different levels of global warming. This report briefly outlines the objectives and framework of the first, fast-tracked phase of Inter-Sectoral Impact Model Intercomparison Project, based on global impact models, and provides an overview of the participating models, input data, and scenario set-up. PMID:24344316

Little River Project.

ERIC Educational Resources Information Center

Naisbitt, Ian

1995-01-01

Describes the adoption of an old riverside landfill by an elementary school as a Habitat 2000 community project. Contains a "how-to" checklist for such a project, information on building school-community community partnerships, and promotional ideas for stewardship projects. (LZ)

40 CFR 403.20 - Pretreatment Program Reinvention Pilot Projects Under Project XL.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 30 2013-07-01 2012-07-01 true Pretreatment Program Reinvention Pilot Projects Under Project XL. 403.20 Section 403.20 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... OF POLLUTION § 403.20 Pretreatment Program Reinvention Pilot Projects Under Project XL. The Approval...

21 CFR 347.3 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-04-01

... FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS FOR HUMAN USE SKIN PROTECTANT DRUG PRODUCTS FOR OVER-THE-COUNTER HUMAN USE General Provisions § 347.3 Definitions. As... plants of the genus Rhus (poison ivy, poison oak, poison sumac), which contain urushiol, a potent skin...

The Overlap Group: A Study of Nonprofit Competition.

ERIC Educational Resources Information Center

Matlock, Thao P.

1994-01-01

In 1991 the Department of Justice brought an antitrust action against the Massachusetts Institute of Technology and eight Ivy League colleges and universities for participating in a financial aid disbursement scheme. Argues that antitrust laws should apply only if competition among nonprofit organizations tends to enhance efficiency and consumer…

Idea Bank.

ERIC Educational Resources Information Center

Science Teacher, 1986

1986-01-01

Provides descriptions of activities and programs that have been successful with secondary science students. Includes ideas related to repairing radio-controlled cars, cooperative science-library center, observation exercises, recordkeeping skills and peer grading, DC power supply, chemistry of poison ivy, spore science, and a tic-tac-toe review…

77 FR 15145 - Ares Capital Corporation et al.;

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-14

...] Ares Capital Corporation et al.; Notice of Application March 9, 2012. AGENCY: Securities and Exchange... Company Act of 1940 (the ``Act'') for an exemption from section 12(d)(3) of the Act. Applicants: Ares Capital Corporation (the ``Company''), Ares Capital Management LLC (``ACM'') and Ivy Hill Asset Management...

The Status of Blacks in Academic Philosophy.

ERIC Educational Resources Information Center

Harris, Leonard

1995-01-01

Reveals that there is a near total absence of black faculty teaching philosophy courses at American universities, particularly Ivy League Schools. The author explains why this has happened, why the trend is likely to continue, and why black colleges cannot be expected to pick up the slack. (GR)

Who Gets In and Why: A Former Admissions Officer Tells All.

ERIC Educational Resources Information Center

Gose, Ben

1997-01-01

A former Dartmouth College (New Hampshire) admissions officer has written a book about the college admissions process at Ivy League and other selective colleges. She details factors in admissions decision making that contradict stated policies and admissions principles. Admissions professionals at Dartmouth and other colleges criticize the book as…

Harvard Project Physics Newsletter 10. The Project Physics Course, Text.

ERIC Educational Resources Information Center

Harvard Univ., Cambridge, MA. Harvard Project Physics.

A short description of the availability of Harvard Project Physics course components is given as is a discussion of the growth of the use of Project Physics in schools, including some enrollment data and survey results. Locations of the 1970 and 1971 Summer Institutes are listed. Adaptations of Project Physics course outside the United States are…

Space Projects: Improvements Needed in Selecting Future Projects for Private Financing

NASA Technical Reports Server (NTRS)

1990-01-01

The Office of Management and Budget (OMB) and NASA jointly selected seven projects for commercialization to reduce NASA's fiscal year 1990 budget request and to help achieve the goal of increasing private sector involvement in space. However, the efforts to privately finance these seven projects did not increase the commercial sector's involvement in space to the extent desired. The General Accounting Office (GAO) determined that the projects selected were not a fair test of the potential of increasing commercial investment in space at an acceptable cost to the government, primarily because the projects were not properly screened. That is, neither their suitability for commercialization nor the economic consequences of seeking private financing for them were adequately evaluated before selection. Evaluations and market tests done after selection showed that most of the projects were not viable candidates for private financing. GAO concluded that projects should not be removed from NASA's budget for commercial development until after careful screening has been done to determine whether adequate commercial demand exists, development risks are commercially acceptable and private financing is found or judged to be highly likely, and the cost effectiveness of such a decision is acceptable. Premature removal of projects from NASA's budget ultimately can cause project delays and increased costs when unsuccessful commercialization candidates must be returned to the budget. NASA also needs to ensure appropriate comparisons of government and private financing options for future commercialization projects.

The Environmental Management Project Manager`s Handbook for improved project definition

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1995-02-01

The United States Department of Energy (DOE) is committed to providing high quality products that satisfy customer needs and are the associated with this goal, DOE personnel must possess the knowledge, skills, and abilities to ensure successful job performance. In addition, there must be recognition that the greatest obstacle to proper project performance is inadequate project definition. Without strong project definition, DOE environmental management efforts are vulnerable to fragmented solutions, duplication of effort, and wastes resources. The primary means of ensuring environmental management projects meet cost and schedule milestones is through a structured and graded approach to project definition, whichmore » is the focus of this handbook.« less

A Qualitative Study of the Relationship between a Banking IT Troubled Project and the Executive Project Sponsor's Project Management Maturity Level

ERIC Educational Resources Information Center

Northcraft, Terry G.

2017-01-01

This qualitative study examined the effect the level of project management maturity a banking IT project sponsor has on project success. Project management maturity is gauged by the amount of modern project management training, knowledge and organizational skills an individual or organization has and applies to their project lifecycle experiences.…

Remote control of regioselectivity in acyl-acyl carrier protein-desaturases.

PubMed

Guy, Jodie E; Whittle, Edward; Moche, Martin; Lengqvist, Johan; Lindqvist, Ylva; Shanklin, John

2011-10-04

Regiospecific desaturation of long-chain saturated fatty acids has been described as approaching the limits of the discriminatory power of enzymes because the substrate entirely lacks distinguishing features close to the site of dehydrogenation. To identify the elusive mechanism underlying regioselectivity, we have determined two crystal structures of the archetypal Δ9 desaturase from castor in complex with acyl carrier protein (ACP), which show the bound ACP ideally situated to position C9 and C10 of the acyl chain adjacent to the diiron active site for Δ9 desaturation. Analysis of the structures and modeling of the complex between the highly homologous ivy Δ4 desaturase and ACP, identified a residue located at the entrance to the binding cavity, Asp280 in the castor desaturase (Lys275 in the ivy desaturase), which is strictly conserved within Δ9 and Δ4 enzymes but differs between them. We hypothesized that interaction between Lys275 and the phosphate of the pantetheine, seen in the ivy model, is key to positioning C4 and C5 adjacent to the diiron center for Δ4 desaturation. Mutating castor Asp280 to Lys resulted in a major shift from Δ9 to Δ4 desaturation. Thus, interaction between desaturase side-chain 280 and phospho-serine 38 of ACP, approximately 27 Å from the site of double-bond formation, predisposes ACP binding that favors either Δ9 or Δ4 desaturation via repulsion (acidic side chain) or attraction (positively charged side chain), respectively. Understanding the mechanism underlying remote control of regioselectivity provides the foundation for reengineering desaturase enzymes to create designer chemical feedstocks that would provide alternatives to those currently obtained from petrochemicals.

Activating the Wnt/β-Catenin Pathway Did Not Protect Immature Retina from Hypoxic-Ischemic Injury.

PubMed

Huang, Hsiu-Mei; Huang, Chao-Ching; Wang, Feng-Sheng; Hung, Pi-Liang; Chang, Ying-Chao

2015-07-01

Visual loss associated with hypoxic-ischemic (HI) brain damage is the most common cause of visual impairment in children of developed countries. A neuroprotective role for Wnt/β-catenin signaling has been demonstrated in several neurodegenerative disorders. The association of Wnt signaling with HI injury in immature retina has not been established. On postnatal day 7 (P7), HI was induced by unilateral common carotid artery ligation followed by 8% oxygen hypoxia for 2 hours. The pups received intravitreous injection (i.v.i) of PBS, Dickkopf-1 (DKK-1, the negative modulator of Wnt/β-catenin pathway) antisense (AS) or sense (S) oligonucleotides at various concentrations for pretreatment (24 and 1 hour before HI) or post treatment (1 and 4 hours after HI). For chronic treatments, animals received repeated intraperitoneal (i.p.) injection of DKK-1-AS, DKK-1-S, lithium chloride (LiCl), or vehicles after HI. The retinal injury was assessed by electroretinography (ERG, P21, and P30) and immunohistochemical staining (P8 or P30). Pretreatment with DKK-1-AS (i.v.i.) attenuated DKK-1 and enhanced β-catenin expression, but did not protect immature retina against HI injury at both pathological and functional levels. Post treatment with DKK-1-AS (i.v.i. or i.p.) also did not rescue HI retinopathy. Chronic systemic LiCl treatment did not decrease Müller cell activation or neuronal damage in HI retinal injury. Our data demonstrated that DKK-1 inhibition or chronic lithium treatment did not protect the immature retina from HI injury. It is speculated that the enhanced canonical Wnt/β-catenin signaling is not sufficient to protect the immature retina from HI injury.

Forecast Inaccuracies in Power Plant Projects From Project Managers' Perspectives

NASA Astrophysics Data System (ADS)

Sanabria, Orlando

Guided by organizational theory, this phenomenological study explored the factors affecting forecast preparation and inaccuracies during the construction of fossil fuel-fired power plants in the United States. Forecast inaccuracies can create financial stress and uncertain profits during the project construction phase. A combination of purposeful and snowball sampling supported the selection of participants. Twenty project managers with over 15 years of experience in power generation and project experience across the United States were interviewed within a 2-month period. From the inductive codification and descriptive analysis, 5 themes emerged: (a) project monitoring, (b) cost control, (c) management review frequency, (d) factors to achieve a precise forecast, and (e) factors causing forecast inaccuracies. The findings of the study showed the factors necessary to achieve a precise forecast includes a detailed project schedule, accurate labor cost estimates, monthly project reviews and risk assessment, and proper utilization of accounting systems to monitor costs. The primary factors reported as causing forecast inaccuracies were cost overruns by subcontractors, scope gaps, labor cost and availability of labor, and equipment and material cost. Results of this study could improve planning accuracy and the effective use of resources during construction of power plants. The study results could contribute to social change by providing a framework to project managers to lessen forecast inaccuracies, and promote construction of power plants that will generate employment opportunities and economic development.

Assessing the Relationship between Ethical Project Management and Information Technology Project Success

ERIC Educational Resources Information Center

Howell, Byron Winter

2010-01-01

The purpose of this quantitative study was to assess the relationship between ethical project management and information technology (IT) project success. The success of IT projects is important for organizational success, but the rate of IT projects is historically low, costing billions of dollars annually. Using four key ethical variables…

FME Senior Project Managers: A Juggling Act of Multiple Projects | Poster

Cancer.gov

By Peggy Pearl, Contributing Writer It was not until the 1950s that organizations in the United States began to apply project management tools and techniques to complex construction and engineering projects (http://en.m.wikipedia.org/wiki/Project_life_cycle).

Project Risk Management

NASA Technical Reports Server (NTRS)

Jr., R. F. Miles

1995-01-01

Project risk management is primarily concerned with performance, reliability, cost, and schedule. Environmental risk management is primarily concerned with human health and ecological hazards and likelihoods. This paper discusses project risk management and compares it to environmental risk management, both with respect to goals and implementation. The approach of the Jet Propulsion Laboratory to risk management is presented as an example of a project risk management approach that is an extension to NASA NHB 7120.5: Management of Major System Programs and Projects.

Research Projects 1968.

ERIC Educational Resources Information Center

Swedish Council for Personnel Administration, Stockholm.

The 39 research projects described cover several fields within the social and behavioral sciences related to personnel administration. The project description format includes: (1) project title, (2) principal investigator, (3) institution, (4) advisor, (5) grants, (6) background and purpose, (7) scope, material, methods, experimental design, (8)…

The Impact of Project Management Maturity upon IT/IS Project Management Outcomes

ERIC Educational Resources Information Center

Carcillo, Anthony Joseph, Jr.

2013-01-01

Although it is assumed that increasing the institutionalization (or maturity) of project management in an organization leads to greater project success, the literature has diverse views. The purpose of this mixed methods study was to examine the correlation between project management maturity and IT/IS project outcomes. The sample consisted of two…

Cooperative Projects - Challenges and Opportunities

NASA Astrophysics Data System (ADS)

Schubotz, Wiebke; Brücher, Tim; Vamborg, Freja

2017-04-01

Today's research in Germany is often organized in large projects and collaborations, so-called cooperative projects ("Verbundprojekte" in German). These projects are defined by a large number of members (more than 50) and participating institutes, e.g. institutes of research organizations such as the Max-Planck society and the Leibniz association, Helmholtz centres, and universities. For coordination purposes these projects usually have a general project manager or project coordinator close to the speaker of the project. Despite this overarching position, it is often challenging for the project manager to really overview the entire project as he is, for example, not involved in the individual institute's recruitment processes or research connections to other institutes via other projects. Additionally, there is neither a formal obligation for the principal investigators and project scientists to report changes within their sub-projects, nor any formal dependency between these sub-projects and the coordination office to ensure a contemporary update of changes and progress in their specific tasks of the project. Therefore, the idea of a coordinating position to oversee the entire cooperative project is sometimes difficult to reach. Furthermore, project managers usually have no formal connection to other project managers. This means that recurrent tasks, for which cooperation between project managers would be helpful, need to be reinvented for each project anew. Due to the lack of this more formalized cooperation between project managers, acquired expertise is often lost. We will illustrate the challenges of this kind of project management based on projects at the Max Planck Institute for Meteorology (Hamburg) and the Helmholtz Centre for Ocean Research (GEOMAR, Kiel), but also point out opportunities that arise within a large collaboration of partners. Moreover, we present an approach to coordinate management processes in order to overcome some of the aforementioned

The Proposal Project

ERIC Educational Resources Information Center

Pierce, Elizabeth

2007-01-01

The proposal project stretches over a significant portion of the semester-long sophomore course Professional Communication (ENG 250) at Monroe Community College. While developing their proposal project, students need to use time management skills to successfully complete a quality project on time. In addition, excellent oral and written…

Ranking the Project Management Success Factors for Construction Project in South India

NASA Astrophysics Data System (ADS)

Aneesha, K.; Haridharan, M. K.

2017-07-01

In Today’s construction industry, to achieve a greater advantage over the firms, success of each project and efficiency is required. Effective Project Management overcomes these types of challenges. This study identifies the success factors which are important for project management in construction project success. From the literature review, 26 factors were found to be critical. Project managers, construction managers, civil engineers, contractors and site engineers were the respondents. After analyzing the data in SPSS software, the dominant factors from the regression analysis are top management support, competent project team, abilities to solve problems, realistic cost and time estimates, information/communication, competency of the project manager are the 6 factors out of 12 in 26 factors. Effective communication between stakeholders got highest priority and client involvement, good leadership, clarity of project goals got second priority. Informal communication gives better results compared to formal communications like written formats. To remove communication barrier with the stakeholders, informal communication like speaking face-to-face with the language this fits for the stakeholders.

Past Project Expo Sites

EPA Pesticide Factsheets

This page provides information for Project Expo sites that were featured at the LMOP Conferences in 2013 and 2014. Project Expo sites were featured as being interested in identifying project partners for the development of an LFG energy project.

A Professor Realizes the Potential Poison of Ivy.

ERIC Educational Resources Information Center

Machell, David F.

1991-01-01

A form of melancholia characterized by the negating of a college faculty member's professional motivation, positive attitudinal focus, and personal self-esteem is described. This "professorial melancholia" has three stages: (1) causal factors are beginning to have an effect; (2) progressive influence and noticeable impact; and (3) serious impact…

Poison ivy: an underreported cause of erythema multiforme.

PubMed

Werchniak, Andrew E; Schwarzenberger, Kathryn

2004-11-01

The relationship between herpes simplex virus (HSV) and erythema multiforme (EM) has been well described. Many authors contend that EM (excluding Stevens-Johnson syndrome and toxic epidermal necrolysis) occurs almost exclusively as a response to HSV infection. During the past year, however, we have observed several cases of EM complicating severe Rhus allergic contact dermatitis. Although this association has been previously documented, the paucity of cases in the literature, along with our experience, suggests that this is an underreported phenomenon. We describe 4 of our cases.

Mechanics of the Adhesive Properties of Ivy Nanoparticles

DTIC Science & Technology

2013-11-21

macromolecule with multiple physiological functions in the growth of plants, such as signaling, cell wall plasticizer, guiding pollen tube growth, and many...others. The AGPs on the stigma surface were believed to act as an adhesive base for pollens , indicating the adhesion function that AGPs play in plants

Simple projects guidebook : federal-aid procedure for simple projects

DOT National Transportation Integrated Search

2002-06-01

Experience has shown that a simple project generally 1) does not have any right-of-way involvement and 2) has a Programmatic Categorical Exclusion or Categorical Exclusion environmental determination. Page 7 outlines the definition of simple projects...

Projection: A Bibliography.

ERIC Educational Resources Information Center

Pedrini, D. T.; Pedrini, Bonnie C.

Sigmund Freud and his associates did much clinical work with the dynamic of projection, especially with regard to paranoid symptoms and syndromes. Much experimental work has also been done with projection. Sears evaluated the results of some of those studies. Murstein and Pryer sub-classified projection and reviewed typical studies. The…

Harvard Observing Project (HOP): Involving Undergraduates in Research Projects

NASA Astrophysics Data System (ADS)

Bieryla, Allyson

2017-01-01

The Harvard Observing Project (HOP) is designed to get students excited about observational astronomy while collecting data valuable to the scientific community. The primary goal is to give undergraduates a chance to try out observing with “no strings attached”. Observations are led by experienced observers, mostly graduate students. This not only gives graduate students extra opportunities to interact and teach undergraduates, but also a chance for them to get more observing experience. Each semester, we choose an interesting target and monitor it each week over the course of the semester using Harvard University’s 16-inch DFM Clay Telescope. These observing projects often produce large amounts of data. This provides an excellent dataset for a young undergraduate to analyze. Some successful semester-long observing projects have included variable stars, supernova and binary systems. Short-term projects have included exoplanet candidate followup, asteroid and comet followup and collaborating with the Pro-Am White Dwarf Monitoring (PAWM) project in attempts to detect a transiting Earth-sized planet orbiting a white dwarf. Each dataset is an opportunity for an undergraduate to be introduced to scientific research and present the results to the community.

Greenery - an opportunity for forest landowners

Treesearch

A.L. Hammett; J.L. Chamberlain

2002-01-01

For generations, materials gathered from American forests have been used for holiday decorations and floral arrangements including Christmas wreaths, roping, swags, and sprays. Forest species utilized for these products include Fraser fir, Norway and blue spruce, mountain laurel, boxwood, ivy, grape vine, juniper, Douglas fir, incense cedar, and holly. White pine (...

EL:?:40

EPA Pesticide Factsheets

2015-09-10

... 'f::f~;~]rt:!t!! 'l?~i:::;,l: ~i,:t:~c; i!i lijkii:~, j1.l: l[:r~r:i;r~fi; ' $,[I::, I:: ji,8[:~t:~ . . Lbji~ivi s:it:)r~ of Techn:i.ca I!, ,,E[$!ly~~r:i.ces & :pdi[:jn:it~:or iLly: (-,, ...

The "Commodification of Higher Education" Myth

ERIC Educational Resources Information Center

Chaplin, David; Forseth, Nate

2015-01-01

Despite concerns over the commodification of higher education in North America, Great Britain, and Oceania (Shumar, 1997; Sappey, 2005; Kaye, Bickel & Birtwistle, 2006; Lewis, 2010) the evidence does not justify such fears. Drawing on price elasticity of demand data and enrollment patterns for public, elite private (Ivy League) and Council for…

Measuring International Service Outcomes: Implications for International Social Work Field Placements

ERIC Educational Resources Information Center

Lough, Benjamin J.; McBride, Amanda Moore; Sherraden, Margaret S.

2012-01-01

International field placements are a unique educational opportunity for social work students to develop the skills they need for social work practice in a globalized world; however, outcomes of international placements have not been rigorously studied. This article reports on the International Volunteer Impacts Survey (IVIS), a 48-item survey…

Along the Pawnee Trail: Cultural Resource Survey and Testing at Wilson Lake, Kansas.

DTIC Science & Technology

1986-08-01

freshwater jellyfish were noted. A variety of pests such as ticks, deer flies, chiggers, wasps, and poison ivy also made themselves evident to the...radiocarbon date of 13,140+100 B.P on mammoth bone collagen indicates a pre-Clovis date for the deposit, but the investigators were cautious about

A Compilation of Federal Education Laws. Volume IV--Vocational Education, Job Training, Rehabilitation and Related Statutes. As Amended through December 31, 1991. Prepared for the Use of the Committee on Education and Labor, U.S. House of Representatives. One Hundred Second Congress, First Session.

ERIC Educational Resources Information Center

Congress of the U.S., Washington, DC. House Committee on Education and Labor.

This document contains the complete text of federal laws related to vocational education, job training, rehabilitation, and related areas as amended through December 31, 1991. Statutes included are the: (1) Carl D. Perkins Vocational Education Act (Titles I-V); (2) Job Training Partnership Act (Titles I-VI); (3) Displaced Homemakers…

Researchers' experience with project management in health and medical research: Results from a post-project review

PubMed Central

2011-01-01

Background Project management is widely used to deliver projects on time, within budget and of defined quality. However, there is little published information describing its use in managing health and medical research projects. We used project management in the Alcohol and Pregnancy Project (2006-2008) http://www.ichr.uwa.edu.au/alcoholandpregnancy and in this paper report researchers' opinions on project management and whether it made a difference to the project. Methods A national interdisciplinary group of 20 researchers, one of whom was the project manager, formed the Steering Committee for the project. We used project management to ensure project outputs and outcomes were achieved and all aspects of the project were planned, implemented, monitored and controlled. Sixteen of the researchers were asked to complete a self administered questionnaire for a post-project review. Results The project was delivered according to the project protocol within the allocated budget and time frame. Fifteen researchers (93.8%) completed a questionnaire. They reported that project management increased the effectiveness of the project, communication, teamwork, and application of the interdisciplinary group of researchers' expertise. They would recommend this type of project management for future projects. Conclusions Our post-project review showed that researchers comprehensively endorsed project management in the Alcohol and Pregnancy Project and agreed that project management had contributed substantially to the research. In future, we will project manage new projects and conduct post-project reviews. The results will be used to encourage continuous learning and continuous improvement of project management, and provide greater transparency and accountability of health and medical research. The use of project management can benefit both management and scientific outcomes of health and medical research projects. PMID:21635721

Post-project geomorphic assessment of a large process-based river restoration project

USGS Publications Warehouse

Erwin, Susannah O.; Schmidt, John C.; Allred, Tyler M.

2016-01-01

This study describes channel changes following completion of the Provo River Restoration Project (PRRP), the largest stream restoration project in Utah and one of the largest projects in the United States in which a gravel-bed river was fully reconstructed. We summarize project objectives and the design process, and we analyze monitoring data collected during the first 7 years after project completion. Post-project channel adjustment during the study period included two phases: (i) an initial phase of rapid, but small-scale, adjustment during the first years after stream flow was introduced to the newly constructed channel and (ii) a subsequent period of more gradual topographic adjustment and channel migration. Analysis of aerial imagery and ground-survey data demonstrate that the channel has been more dynamic in the downstream 4 km where a local source contributes a significant annual supply of bed material. Here, the channel migrates and exhibits channel adjustments that are more consistent with project objectives. The upstream 12 km of the PRRP are sediment starved, the channel has been laterally stable, and this condition may not be consistent with large-scale project objectives.

The Sidewalk Project

ERIC Educational Resources Information Center

Church, William

2005-01-01

In this article, the author features "the sidewalk project" in Littleton High School. The sidewalk project is a collaboration of more than 40 high school physics students, 10 local mentors, and a few regional and national organizations who worked together to invent a way to heat a sidewalk with an alternative energy source. The project, which…

Designing Effective Projects: Decision Options for Maximizing Learning and Project Success

ERIC Educational Resources Information Center

Volkema, Roger J.

2010-01-01

In recent years, more and more business schools have introduced team-based projects into their curricula as a means of addressing corporate, small business, and community-service issues while teaching students a variety of project management skills (technical and sociocultural). In designing a project-oriented course, an instructor has a number of…

The Project Approach Catalog 2 by the Project Approach Study Group.

ERIC Educational Resources Information Center

Helm, Judy Harris, Ed.

Projects are in-depth studies of a topic undertaken by a class, a group, or an individual child. Projects are intended to strengthen children's dispositions to be interested, absorbed, and involved in in-depth observation, investigation, and representation of worthwhile phenomena in their own environments. This Catalog on the Project Approach, the…

Project Lodestar Special Report.

ERIC Educational Resources Information Center

Brown, Peggy, Ed.

1981-01-01

The Association of American Colleges' (AAC) Project Lodestar is addressed in an article and descriptions of the pilot phase of the project at 13 institutions. In "Project Lodestar: Realistically Assessing the Future," Peggy Brown provides an overview of the project, which is designed to help colleges and universities in assessment of…

Project CHECO Southeast Asia Report. Project RED HORSE

DTIC Science & Technology

1969-09-01

It 0,Il 1IC1I lll Examination of C’urrentI,,,,,,,,[ I prations IIR / IE IP𔃻 0 R IT - PROJECT RED HORSE 1 SEPTEMBER 1969 HQ PACAF Directorate...3 CHAPTER II RED HORSE ORGANIZATIONS IN SOUTHEAST ASIA .................. 5 Introduction...RED HORSE Combat Defense Teams....................... ...... 59 III. 555th CES (HR) Projects...................................... 62 IV. 820th CES

Project CLIMB.

ERIC Educational Resources Information Center

DeLucca, Adolph

1982-01-01

As a state and national model for a basic skills curriculum for Kindergarten through grade 12 students, Coordination Learning Integration--Middlesex Basics (Project CLIMB) is described. The unified system was developed by teachers with administrative support to accomodate all students' reading and mathematics needs. Project CLIMB's development and…

Puerto Rico`s EcoElectrica LNG/power project marks a project financing first

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lammers, R.; Taylor, S.

1998-02-23

On Dec. 15, 1997, Enron International and Kenetech Energy Services achieved financial close on the $670 million EcoElectrica liquefied natural gas terminal and cogeneration project proposed for Puerto Rico. The project involves construction of a liquefied natural gas terminal, cogeneration plant, and desalination unit on the southern coast of Puerto Rico, in the Penuelas/Guayanilla area. EcoElectrica will include a 500-mw, combined-cycle cogeneration power plant fueled mainly by LNG imported from the 400 MMcfd Atlantic LNG project on the island of Trinidad. Achieving financial close on a project of this size is always a time-consuming matter and one with a numbermore » of challenges. These challenges were increased by the unique nature of both the project and its financing--no project financing had ever before been completed that combined an LNG terminal and power plant. The paper discusses the project, financing details and challenges, key investment considerations, and integrated project prospects.« less

Flat-plate solar array project. Volume 8: Project analysis and integration

NASA Technical Reports Server (NTRS)

Mcguire, P.; Henry, P.

1986-01-01

Project Analysis and Integration (PA&I) performed planning and integration activities to support management of the various Flat-Plate Solar Array (FSA) Project R&D activities. Technical and economic goals were established by PA&I for each R&D task within the project to coordinate the thrust toward the National Photovoltaic Program goals. A sophisticated computer modeling capability was developed to assess technical progress toward meeting the economic goals. These models included a manufacturing facility simulation, a photovoltaic power station simulation and a decision aid model incorporating uncertainty. This family of analysis tools was used to track the progress of the technology and to explore the effects of alternative technical paths. Numerous studies conducted by PA&I signaled the achievement of milestones or were the foundation of major FSA project and national program decisions. The most important PA&I activities during the project history are summarized. The PA&I planning function is discussed and how it relates to project direction and important analytical models developed by PA&I for its analytical and assessment activities are reviewed.

The Canada Goose Project: A First Project with Children under 3

ERIC Educational Resources Information Center

Brewer, Ruth A.

2010-01-01

This project report describes how five children (an infant, three toddlers, and a preschooler) enrolled at a private day care home engaged in their first journey into project work through a study of Canada geese living on a nearby body of water. Prior to the experience described in this paper, the author had used the Project Approach only with…

Project-based fieldwork: perspectives of graduate entry students and project sponsors.

PubMed

Fortune, Tracy; McKinstry, Carol

2012-08-01

This article builds on an earlier viewpoint regarding the need for project-focussed fieldwork. It presents the findings of an evaluative study into the value of project placements undertaken by final year graduate entry master's students as part of a capstone subject. The authors argue that provision of project placements enable impending graduates to develop and implement macro level strategies to develop prevention, resource and service development skills often required of contemporary occupational therapy practitioners. A qualitative approach is adopted. Student cohorts from 2005 and 2006 completed open-ended, written questionnaires, and agency project sponsors were interviewed to obtain their perspectives of the project placement experience. Despite some concern that project placements might be undertaken at the expense of 'clinical' placements these findings reveal that projects managed by students were perceived by services to add great value enabling them to advance important priorities. Students and sponsors highlighted a range of positive learning outcomes, including the ability to work collaboratively with supervisors and develop advanced communication skills and political acumen. The success of such placements depends on supportive supervision from academic staff. CONCLUSIONS AND SIGNIFICANCE OF THE STUDY: The findings promote project placements as a highly authentic aspect of work integrated learning enabling learners to draw together a range of attributes that support the ability to manage complex issues that have occupational relevance at a macro level. In addition, such experiences help learners to develop agency and political acumen both increasingly important capabilities for the contemporary workplace. © 2012 The Authors Australian Occupational Therapy Journal © 2012 Occupational Therapy Australia.

Earth System Science Project

ERIC Educational Resources Information Center

Rutherford, Sandra; Coffman, Margaret

2004-01-01

For several decades, science teachers have used bottles for classroom projects designed to teach students about biology. Bottle projects do not have to just focus on biology, however. These projects can also be used to engage students in Earth science topics. This article describes the Earth System Science Project, which was adapted and developed…

Interactions of the NAEG information support project with other projects

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pfuderer, H.A.

In the past year the Information Support Project to the Nevada Applied Ecology Group has interacted with many other research projects on the transuranics and other radionuclides. Group interactions through symposiums, workshops, and responding to search requests have proven to be mutually beneficial. The NAEG Information Support Project will draw on the information resources of the Oak Ridge National Laboratory to produce a bibliography of the radionuclides (other than the transuranics) of interest to the Nevada Test Site. (auth)

Scaffolding Project-Based Learning with the Project Management Body of Knowledge (PMBOK[R])

ERIC Educational Resources Information Center

van Rooij, Shahron Williams

2009-01-01

This paper reports the results of a study of the extent to which processes and procedures from the discipline of project management can scaffold online project-based learning in a graduate-level instructional technology course, by facilitating intra-team interaction, enhancing project outcomes and promoting a positive project team experience. With…

Punting Our Future: College Athletics and Admissions

ERIC Educational Resources Information Center

Fried, Barbara H.

2007-01-01

Jeremiads about intercollegiate sports have been around for about as long as intercollegiate sports. In recent decades, critics have focused on headlines about abuses involving the big-time, NCAA Division IA sports teams, citing elite Division III schools and Ivy League schools as the poster children for reform. Unlike Division IA programs, whose…

Diversity and Senior Leadership at Elite Institutions of Higher Education

ERIC Educational Resources Information Center

Gasman, Marybeth; Abiola, Ufuoma; Travers, Christopher

2015-01-01

This article explores the lack of diversity at the 8 Ivy League institutions using a Critical Race Theory lens. It includes a comprehensive literature review of the scholarship related to diversity in academe, but especially within the areas of elite institutions and administration. The article also provides data pertaining to the senior…

Commodity Ed

ERIC Educational Resources Information Center

Waters, John K.

2013-01-01

With schools and students now able to secure high-quality online courses from beyond the ivy-covered walls, faculty--and institutions themselves--are weighing whether their stock is rising or falling. Increasingly, online courses and their content--previously the jealously guarded domain of professors--are being offered as out-of-the-box solutions…

The Grapes of Class: Teaching Chemistry Concepts at a Winery

ERIC Educational Resources Information Center

Luck, Linda A.; Blondo, Ryan M.

2012-01-01

Nonscience majors often believe that the concepts and techniques in chemistry have little relevance to someone outside the "ivy-covered walls of academia". The challenge for science instructors is to develop and implement lessons that present science in a way that will capture the interest of the nonscience major, while remaining rigorous enough…

STS-133 crew members Lindsey, Boe and Drew during Tool/Repair Kits training with instructor

NASA Image and Video Library

2010-01-26

JSC2010-E-014262 (26 Jan. 2010) --- NASA astronauts Eric Boe (left), STS-133 pilot; Steve Lindsey, commander; and Alvin Drew, mission specialist, participate in an ISS tools and repair kits training session in the Space Vehicle Mock-up Facility at NASA's Johnson Space Center. Instructor Ivy Apostolakopoulos assisted the crew members.

Pesticide Applicator Training Manual, Category 8A: General Public Health Pest Control for New Jersey. A Training Program for the Certification of Commercial Pesticide Applicators, and Study Questions.

ERIC Educational Resources Information Center

Schulze, Terry L.; Kriner, Ray R.

This training manual provides information needed to meet the minimum EPA standards for certification as a commercial applicator of pesticides in the public health pest control category. The text discusses invertebrate pests such as cockroaches, lice, fleas, and mites, vertebrate pests; and plant pests such as poison ivy and ragweed. A study guide…

Game Playing: Negotiating Rules and Identities

ERIC Educational Resources Information Center

Winther-Lindqvist, Ditte

2009-01-01

Beginning with Lev Vygotsky's long-established assertion that the play of children always involves both imaginary play and rules of behavior, this article argues for a theoretical framework that connects such play with the construction of social identities in kindergarten peer groups. It begins with a discussion of Ivy Schousboe's model of the…

The Changing Face of Student Aid

ERIC Educational Resources Information Center

Farrell, Elizabeth F.

2008-01-01

A recent flurry of announcements from some of the wealthiest and most competitive private colleges brought welcome news to lower- and middle-income families. Many Ivy League institutions, along with dozens of smaller colleges that also attract high-achieving students, unveiled student-aid plans that will significantly lower the cost of attendance…

21 CFR 347.3 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-04-01

... SKIN PROTECTANT DRUG PRODUCTS FOR OVER-THE-COUNTER HUMAN USE General Provisions § 347.3 Definitions. As used in this part: Astringent drug product. A drug product applied to the skin or mucous membranes for... plants of the genus Rhus (poison ivy, poison oak, poison sumac), which contain urushiol, a potent skin...

NCMS ESS 2000 Project

NASA Technical Reports Server (NTRS)

Gibbel, Mark; Bellamy, Marvin; DeSantis, Charlie; Hess, John; Pattok, Tracy; Quintero, Andrew; Silver, R.

1996-01-01

ESS 2000 has the vision of enhancing the knowledge necessary to implement cost-effective, leading-edge ESS technologies and procedures in order to increase U.S. electronics industry competitiveness. This paper defines EES and discusses the factors driving the project, the objectives of the project, its participants, the three phases of the project, the technologies involved, and project deliverables.

The 100 People Project

ERIC Educational Resources Information Center

McLeod, Keri

2007-01-01

This article describes the 100 People Project and how the author integrates the project in her class. The 100 People Project is a nonprofit organization based in New York City. The organization poses the question: If there were only 100 people in the world, what would the world look like? Through the project, students were taught about ethics in…

KSC History Project

NASA Technical Reports Server (NTRS)

Dethloff, Henry C.

2001-01-01

The KSC History Project focuses on archival research and oral history interviews on the history of Kennedy Space Center (KSC). Related projects include the preparation of a precis and chapter outline for a proposed book-length narrative history, a bibliography of key primary and secondary resources, a brief monograph overview of the history of KSC, and a monograph on the history of safety at the Center. Finally, there is work on the development of a web page and a personal history data base associated with the oral history project. The KSC History Project has been a joint endeavor between Henry C. Dethloff and Dr. Noble Lee Snaples, Jr.

Sliding Window Generalized Kernel Affine Projection Algorithm Using Projection Mappings

NASA Astrophysics Data System (ADS)

Slavakis, Konstantinos; Theodoridis, Sergios

2008-12-01

Very recently, a solution to the kernel-based online classification problem has been given by the adaptive projected subgradient method (APSM). The developed algorithm can be considered as a generalization of a kernel affine projection algorithm (APA) and the kernel normalized least mean squares (NLMS). Furthermore, sparsification of the resulting kernel series expansion was achieved by imposing a closed ball (convex set) constraint on the norm of the classifiers. This paper presents another sparsification method for the APSM approach to the online classification task by generating a sequence of linear subspaces in a reproducing kernel Hilbert space (RKHS). To cope with the inherent memory limitations of online systems and to embed tracking capabilities to the design, an upper bound on the dimension of the linear subspaces is imposed. The underlying principle of the design is the notion of projection mappings. Classification is performed by metric projection mappings, sparsification is achieved by orthogonal projections, while the online system's memory requirements and tracking are attained by oblique projections. The resulting sparsification scheme shows strong similarities with the classical sliding window adaptive schemes. The proposed design is validated by the adaptive equalization problem of a nonlinear communication channel, and is compared with classical and recent stochastic gradient descent techniques, as well as with the APSM's solution where sparsification is performed by a closed ball constraint on the norm of the classifiers.

Innovative Project Activities in Science [From the NSTA Study of Innovative Project Activities

ERIC Educational Resources Information Center

Science Teacher, 1975

1975-01-01

Describes four projects chosen as innovative project activities in science which exhibited identification of unique or novel problems and creative approaches to their solutions. Projects included a study of fish in Lake Erie, a goat raising project, an analysis of terrestrial plant ecology and soil composition, and a study of marine and wetlands…

Managing Projects with KPRO

NASA Technical Reports Server (NTRS)

Braden, Barry M.

2004-01-01

How does a Project Management Office provide: Consistent, familiar, easily used scheduling tools to Project Managers and project team members? Provide a complete list of organization resources available for use on the project? Facilitate resource tracking and visibility? Provide the myriad reports that the organization requires? Facilitate consistent budget planning and cost performance information? Provide all of this to the entire organization? Provide for the unique requirement of the organization? and get people to use it? Answer: Implementation of the Kennedy space Center Projects and Resources Online (KPRO), a modified COTS solution.

Fourth Year Status Report. Computerized Training Systems Project. Project ABACUS.

DTIC Science & Technology

1976-08-01

in 7 9. PERFORMING ORGANIZATION NAME AND ADOMEN ,,, 10. PROGRAM ELEMENT. PROJECT , TASK US Army Tra ining Support Center A R E A S WORK UNIT NUMBERS...transp ired during the fourth year of Project ABACUS, the A rmy ’s program for the development of a Computerized Training System. It inc l udes a...have transpired durlnq the fourth year of Project ABACUS, the Army ’s program for the developmen t o~ aprototype Computer i zed Training System. It

Project Wild (Project Tame).

ERIC Educational Resources Information Center

Siegenthaler, David

For 37 states in the United States, Project Wild has become an officially sanctioned, distributed and funded "environemtnal and conservation education program." For those who are striving to implement focused, sequential, learning programs, as well as those who wish to promote harmony through a non-anthropocentric world view, Project…

Program and Project Management Framework

NASA Technical Reports Server (NTRS)

Butler, Cassandra D.

2002-01-01

The primary objective of this project was to develop a framework and system architecture for integrating program and project management tools that may be applied consistently throughout Kennedy Space Center (KSC) to optimize planning, cost estimating, risk management, and project control. Project management methodology used in building interactive systems to accommodate the needs of the project managers is applied as a key component in assessing the usefulness and applicability of the framework and tools developed. Research for the project included investigation and analysis of industrial practices, KSC standards, policies, and techniques, Systems Management Office (SMO) personnel, and other documented experiences of project management experts. In addition, this project documents best practices derived from the literature as well as new or developing project management models, practices, and techniques.

The Human Genome Diversity Project

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cavalli-Sforza, L.

1994-12-31

The Human Genome Diversity Project (HGD Project) is an international anthropology project that seeks to study the genetic richness of the entire human species. This kind of genetic information can add a unique thread to the tapestry knowledge of humanity. Culture, environment, history, and other factors are often more important, but humanity`s genetic heritage, when analyzed with recent technology, brings another type of evidence for understanding species` past and present. The Project will deepen the understanding of this genetic richness and show both humanity`s diversity and its deep and underlying unity. The HGD Project is still largely in its planningmore » stages, seeking the best ways to reach its goals. The continuing discussions of the Project, throughout the world, should improve the plans for the Project and their implementation. The Project is as global as humanity itself; its implementation will require the kinds of partnerships among different nations and cultures that make the involvement of UNESCO and other international organizations particularly appropriate. The author will briefly discuss the Project`s history, describe the Project, set out the core principles of the Project, and demonstrate how the Project will help combat the scourge of racism.« less

Mercury Project

NASA Image and Video Library

1959-04-27

Astronaut L. Gordon Cooper, Jr., one of the original seven astronauts for Mercury Project selected by NASA on April 27, 1959. The MA-9 mission, boosted by the Mercury-Atlas launch vehicle, was the last flight of the Mercury Project. The Faith 7 spacecraft orbited the Earth 22 times in 1-1/2 days.

We Scrum Every Day: Using Scrum Project Management Framework for Group Projects

ERIC Educational Resources Information Center

Pope-Ruark, Rebecca

2012-01-01

Collaborative group projects have documented learning benefits, yet collaboration is challenging for students because the educational system values individual achievement. This article explores Scrum, an approach to framing, planning, and managing group projects used in Web-software development. Designed for multi-faceted projects, this approach…

Determinants of project success

NASA Technical Reports Server (NTRS)

Murphy, D. C.; Baker, B. N.; Fisher, D.

1974-01-01

The interactions of numerous project characteristics, with particular reference to project performance, were studied. Determinants of success are identified along with the accompanying implications for client organization, parent organization, project organization, and future research. Variables are selected which are found to have the greatest impact on project outcome, and the methodology and analytic techniques to be employed in identification of those variables are discussed.

Project HIRE.

ERIC Educational Resources Information Center

Weisz, Vera C.

Project HIRE is a special program conducted by Middlesex Community College since October 1978 to help people 55 years of age and older find paid employment. The specific goals of the project, as it was originally conceived, were to: (1) open three intake centers; (2) register clients at the centers; (3) provide career counseling; (4) offer…

Project Management in Real Time: A Service-Learning Project

ERIC Educational Resources Information Center

Larson, Erik; Drexler, John A., Jr.

2010-01-01

This article describes a service-learning assignment for a project management course. It is designed to facilitate hands-on student learning of both the technical and the interpersonal aspects of project management, and it involves student engagement with real customers and real stakeholders in the creation of real events with real outcomes. As…

Evaluation of Project Symbiosis: An Interdisciplinary Science Education Project.

ERIC Educational Resources Information Center

Altschuld, James W.

1993-01-01

The goal of this report is to provide a summary of the evaluation of Project Symbiosis which focused on enhancing the teaching of science principles in high school agriculture courses. The project initially involved 15 teams of science and agriculture teachers and was characterized by an extensive evaluation component consisting of six formal…

Iliac Vein Interrogation Augments Venous Ulcer Healing in Patients Who Have Failed Standard Compression Therapy along with Pathological Venous Closure.

PubMed

Mousa, Albeir Y; Broce, Mike; Yacoub, Michael; AbuRahma, Ali F

2016-07-01

Treatment of venous ulcers is demanding for patients, as well as clinicians, and the investigation of underlying venous hypertension is the cornerstone of therapy. We propose that occult iliac vein stenosis should be ruled out by iliac vein interrogation (IVI) in patients with advanced venous stasis. We conducted a systematic retrospective analysis of a consecutive series of patients who presented with CEAP (clinical, etiological, anatomical, and pathophysiological) 6 venous disease. All patients had great saphenous vein ablation, compressive treatment, wound care (including Unna boot compression), and perforator closure using ablation therapy. Iliac vein stenosis was defined as ≥50% stenosis in cross-sectional surface area on intravascular ultrasound. Primary outcomes include time of venous ulcer healing and/or measurable change in the Venous Clinical Severity Score. Twenty-two patients with CEAP 6 venous disease met the inclusion criteria (active ulcers >1.5 cm in diameter). The average age and body mass index were 62.2 ± 9.2 years and 41.7 ± 16.7, respectively. The majority were female (72.7%) with common comorbidities, such as hyperlipidemia (54.5%), hypertension (36.4%), and diabetes mellitus (27.3%). Twenty-nine ulcers with an average diameter of 3.4 ± 1.9 cm and a depth of 2.2 ± 0.5 mm were treated. The majority of the ulcers occurred on the left limb (n = 17, 58.6%). Average perforator venous reflux was 3.6 ± 0.8 sec, while common femoral reflux was 1.8 ± 1.6. The majority (n = 19, 64.5%) of the perforator veins were located at the base of the ulcer, while the remainder (n = 10, 34.5%) were within 2 cm from the base. Of the 13 patients who underwent IVI, 8 patients (61.5%) had stenosis >50% that was corrected with iliac vein angioplasty and stenting (IVAS). There was a strong trend toward shorter healing time in the IVI group (7.9 ± 9.5 weeks) than for patients in the no iliac vein interrogation (NIVI) group (20.2 ± 15

The project management office: transforming healthcare in the context of a hospital redevelopment project.

PubMed

Richer, Marie-Claire; Marchionni, Caroline; Lavoie-Tremblay, Melanie; Aubry, Monique

2013-01-01

It has been shown that classifying projects into a typology allows improved allocation of resources and promotes project success. However, a typology of healthcare projects has yet to be developed. The projects encountered by the Transition Support Office at the McGill University Health Centre in Montreal, Quebec, where a major redevelopment project is under way, were classified into a typology unique to the healthcare context. Examples of the 3 project types, Process, People, and Practice, are provided to clarify the specific support strategies and context-adapted interventions that were instrumental to their success.

Project Management for International Development.

ERIC Educational Resources Information Center

Axelrod, Valija M.; Magisos, Joel H.

A project developed a content model for international project management training. It also compiled a bibliography of project management references, identified specific project management training needs based upon a survey of international sponsors and contractor personnel, and documented the training needs of international project managers. Data…

Multi-Role Project (MRP): A New Project-Based Learning Method for STEM

ERIC Educational Resources Information Center

Warin, Bruno; Talbi, Omar; Kolski, Christophe; Hoogstoel, Frédéric

2016-01-01

This paper presents the "Multi-Role Project" method (MRP), a broadly applicable project-based learning method, and describes its implementation and evaluation in the context of a Science, Technology, Engineering, and Mathematics (STEM) course. The MRP method is designed around a meta-principle that considers the project learning activity…

KSC History Project

NASA Technical Reports Server (NTRS)

Snaples, Lee

2001-01-01

The project is a joint endeavor between Dr. Henry Dethloff and myself and is producing a number of products related to KSC history. This report is a summary of those projects. First, there is an overview monograph covering KSC history. Second, there is a chapter outline for an eventual book-length history. Third, there is monograph on safety at KSC. Finally, there is a web page and database dedicated to the KSC oral history project.

Project ArchimedeZ

DTIC Science & Technology

2015-05-18

of information is estimated to average 1 hour per response, including the time for reviewing instructions, searching existing data sources, gathering...describe the proposed content of Project ArchimedeZ, 4 ) describe incentives that Project ArchimedeZ will give to Total Force Airmen to participate and...engaged, most of the time, in some sort of PME but at a manageable level. Rather than a three- hour block, for example, Project ArchimedeZ would deliver

Adding access to a video magnifier to standard vision rehabilitation: initial results on reading performance and well-being from a prospective, randomized study.

PubMed

Jackson, Mary Lou; Schoessow, Kimberly A; Selivanova, Alexandra; Wallis, Jennifer

2017-01-01

Both optical and electronic magnification are available to patients with low vision. Electronic video magnifiers are more expensive than optical magnifiers, but they offer additional benefits, including variable magnification and contrast. This study aimed to evaluate the effect of access to a video magnifier (VM) added to standard comprehensive vision rehabilitation (VR). In this prospective study, 37 subjects with central field loss were randomized to receive standard VR (VR group, 18 subjects) or standard VR plus VM (VM group, 19 subjects). Subjects read the International Reading Speed Texts (IReST), a bank check, and a phone number at enrollment, at 1 month, and after occupational therapy (OT) as indicated to address patient goals. The Impact of Vision Impairment (IVI) questionnaire, a version of the Activity Inventory (AI), and the Depression Anxiety and Stress Scale (DASS) were administered at enrollment, 1 month, after OT, 1 month later, and 1 year after enrollment. Assessments at enrollment and 1 month later were evaluated. At 1 month, the VM group displayed significant improvement in reading continuous print as measured by the IReST ( P = 0.01) but did not differ on IVI, AI, or DASS. From enrollment to 1 month all subjects improved in their ability to spot read (phone number and check; P < 0.01 for both). The VM group improved in their ability to find and read a number in a phone book more than the VR group at 1 month after initial consultation ( P = 0.02). All reported better well-being ( P = 0.02). All subjects reported better well-being on the IVI. The VM group read faster and was better at two spot reading tasks but did not differ from the VR group in other outcome measures.

Adding access to a video magnifier to standard vision rehabilitation: initial results on reading performance and well-being from a prospective, randomized study

PubMed Central

Jackson, Mary Lou; Schoessow, Kimberly A.; Selivanova, Alexandra; Wallis, Jennifer

2017-01-01

Purpose Both optical and electronic magnification are available to patients with low vision. Electronic video magnifiers are more expensive than optical magnifiers, but they offer additional benefits, including variable magnification and contrast. This study aimed to evaluate the effect of access to a video magnifier (VM) added to standard comprehensive vision rehabilitation (VR). Methods In this prospective study, 37 subjects with central field loss were randomized to receive standard VR (VR group, 18 subjects) or standard VR plus VM (VM group, 19 subjects). Subjects read the International Reading Speed Texts (IReST), a bank check, and a phone number at enrollment, at 1 month, and after occupational therapy (OT) as indicated to address patient goals. The Impact of Vision Impairment (IVI) questionnaire, a version of the Activity Inventory (AI), and the Depression Anxiety and Stress Scale (DASS) were administered at enrollment, 1 month, after OT, 1 month later, and 1 year after enrollment. Assessments at enrollment and 1 month later were evaluated. Results At 1 month, the VM group displayed significant improvement in reading continuous print as measured by the IReST (P = 0.01) but did not differ on IVI, AI, or DASS. From enrollment to 1 month all subjects improved in their ability to spot read (phone number and check; P < 0.01 for both). The VM group improved in their ability to find and read a number in a phone book more than the VR group at 1 month after initial consultation (P = 0.02). All reported better well-being (P = 0.02). Conclusions All subjects reported better well-being on the IVI. The VM group read faster and was better at two spot reading tasks but did not differ from the VR group in other outcome measures. PMID:28924412

Outcomes of 23-gauge transconjunctival sutureless vitrectomy for acute postoperative endophthalmitis.

PubMed

Hsu, Chia-Ming; Chen, Shih-Chou; Wu, Tsung-Tien; Sheu, Shwu-Jiuan

2017-08-01

To report our 3-year experience of 23-gauge transconjunctival sutureless vitrectomy (TSV) for acute postoperative endophthalmitis at a tertiary referral center in southern Taiwan. This retrospective chart review study included 19 patients with acute postoperative endophthalmitis who underwent 23-gauge TSV from January 2011 to January 2015 at Kaohsiung Veterans General Hospital, Taiwan. Bacterial and fungal cultures from aqueous samples, vitreous samples, or both were performed. Nineteen patients (12 male; 7 female) were included. The mean age was 72.4 ± 8.29 years. Acute postoperative endophthalmitis was noted in 18 patients after cataract surgery and in 1 patient after 23-gauge vitrectomy for a rhegmatogenous retinal detachment. Upon presentation, visual acuity was less than hand movement for 80% of the patients. Chief complaints included blurred vision (19 patients, 100%), followed by pain (10 patients, 52.6%) and red eye (4 patients, 21%). All patients were administered an intravitreal injection (IVI) of antibiotics and 23-gauge TSV, and the average number of IVIs was 2.68 ± 1.73 (1-9 IVIs). The interval between their initial eye symptoms and vitrectomy was 4.11 ± 4.73 days (0-2 days), and the interval between diagnosis with endophthalmitis and a vitrectomy was 1.11 ± 1.52 days (0-6 days). The final visual acuity was no light perception for 1 patient (5.3%), between 6/60 and 6/12 for 8 patients (42.1%), and 6/12 or better for 9 patients (47.4%). No retinal detachment or hypotony was noted postoperatively in any case. 23-gauge vitrectomy is safe and effective for the management of acute postoperative endophthalmitis. Early diagnosis and treatment with 23-gauge vitrectomy may provide a good visual outcome. Copyright © 2017. Published by Elsevier Taiwan LLC.

Toward best practice in Human Machine Interface design for older drivers: A review of current design guidelines.

PubMed

Young, K L; Koppel, S; Charlton, J L

2017-09-01

Older adults are the fastest growing segment of the driving population. While there is a strong emphasis for older people to maintain their mobility, the safety of older drivers is a serious community concern. Frailty and declines in a range of age-related sensory, cognitive, and physical impairments can place older drivers at an increased risk of crash-related injuries and death. A number of studies have indicated that in-vehicle technologies such as Advanced Driver Assistance Systems (ADAS) and In-Vehicle Information Systems (IVIS) may provide assistance to older drivers. However, these technologies will only benefit older drivers if their design is congruent with the complex needs and diverse abilities of this driving cohort. The design of ADAS and IVIS is largely informed by automotive Human Machine Interface (HMI) guidelines. However, it is unclear to what extent the declining sensory, cognitive and physical capabilities of older drivers are addressed in the current guidelines. This paper provides a review of key current design guidelines for IVIS and ADAS with respect to the extent they address age-related changes in functional capacities. The review revealed that most of the HMI guidelines do not address design issues related to older driver impairments. In fact, in many guidelines driver age and sensory cognitive and physical impairments are not mentioned at all and where reference is made, it is typically very broad. Prescriptive advice on how to actually design a system so that it addresses the needs and limitations of older drivers is not provided. In order for older drivers to reap the full benefits that in-vehicle technology can afford, it is critical that further work establish how older driver limitations and capabilities can be supported by the system design process, including their inclusion into HMI design guidelines. Copyright © 2016 Elsevier Ltd. All rights reserved.

Remote control of regioselectivity in acyl-acyl carrier protein-desaturases

PubMed Central

Guy, Jodie E.; Whittle, Edward; Moche, Martin; Lengqvist, Johan; Lindqvist, Ylva; Shanklin, John

2011-01-01

Regiospecific desaturation of long-chain saturated fatty acids has been described as approaching the limits of the discriminatory power of enzymes because the substrate entirely lacks distinguishing features close to the site of dehydrogenation. To identify the elusive mechanism underlying regioselectivity, we have determined two crystal structures of the archetypal Δ9 desaturase from castor in complex with acyl carrier protein (ACP), which show the bound ACP ideally situated to position C9 and C10 of the acyl chain adjacent to the diiron active site for Δ9 desaturation. Analysis of the structures and modeling of the complex between the highly homologous ivy Δ4 desaturase and ACP, identified a residue located at the entrance to the binding cavity, Asp280 in the castor desaturase (Lys275 in the ivy desaturase), which is strictly conserved within Δ9 and Δ4 enzymes but differs between them. We hypothesized that interaction between Lys275 and the phosphate of the pantetheine, seen in the ivy model, is key to positioning C4 and C5 adjacent to the diiron center for Δ4 desaturation. Mutating castor Asp280 to Lys resulted in a major shift from Δ9 to Δ4 desaturation. Thus, interaction between desaturase side-chain 280 and phospho-serine 38 of ACP, approximately 27 Å from the site of double-bond formation, predisposes ACP binding that favors either Δ9 or Δ4 desaturation via repulsion (acidic side chain) or attraction (positively charged side chain), respectively. Understanding the mechanism underlying remote control of regioselectivity provides the foundation for reengineering desaturase enzymes to create designer chemical feedstocks that would provide alternatives to those currently obtained from petrochemicals. PMID:21930947

Patient pain during intravitreal injections under topical anesthesia: a systematic review.

PubMed

Shiroma, Helio Francisco; Takaschima, Augusto Key Karazawa; Farah, Michel Eid; Höfling-Lima, Ana Luisa; de Luca Canto, Graziela; Benedetti, Roberto Henrique; Rodrigues, Eduardo Buchele

2017-01-01

Intravitreal injection (IVI) is a very common vitreoretinal procedure, and multiple injections are often required per patient. This systematic review was conducted to evaluate the effectiveness of various local anesthetic techniques in reducing pain during injection. A systematic review was conducted based on searches of Cochrane, LILACS, PubMed, Scopus, Web of Science, and the gray literature (Google Scholar). The end search date was February 19, 2016, across all databases. We classified pain by converting visual analog scale (VAS) scores (0-100 mm) into Jensen's classification levels: 0-4, no pain; 5-44, mild pain; 45-74, moderate pain; and 75-100, severe pain. An intervention was considered clinically significant when pain score change was >12 mm on a 100-mm scale. Eight studies out of 23 met the eligibility criteria. The total number of patients was 847. Most studies (5/8 [62.5%]) were at unclear risk of bias because of unclear randomization, thus providing only moderate evidence to this review. The anesthetic techniques included eye drops with proparacaine, tetracaine or cocaine, a lidocaine pledget or gel, and subconjunctival injection of 2% lidocaine or 0.75% levobupivacaine. No study comprised all of the techniques. Pain was mild (VAS scores, 5-44 mm) regardless of anesthetic technique. A clinically significant intervention (pain score change >12 mm) was found for only one study comparing proparacaine drops, lidocaine gel, and subconjunctival lidocaine; in that study, a subconjunctival injection of 2% lidocaine provided the greatest pain reduction. A meta-analysis was not possible due to study heterogeneity. Patient pain during IVI under topical anesthesia is mild regardless of anesthetic technique. A subconjunctival injection of 2% lidocaine could be an option for highly sensitive patients. However, with moderate level of evidence, no single anesthetic technique could be defined as the best option for IVI.

Servant leadership behaviors of aerospace and defense project managers and their relation to project success

NASA Astrophysics Data System (ADS)

Dominik, Michael T.

The success of a project is dependent in part on the skills, knowledge, and behavior of its leader, the project manager. Despite advances in project manager certifications and professional development, the aerospace and defense industry has continued to see highly visible and expensive project failures partially attributable to failures in leadership. Servant leadership is an emerging leadership theory whose practitioners embrace empowerment, authenticity, humility, accountability, forgiveness, courage, standing back, and stewardship, but has not yet been fully examined in the context of the project manager as leader. The objective of this study was to examine the relationship between servant leadership behaviors demonstrated by aerospace and defense project managers and the resulting success of their projects. Study participants were drawn from aerospace and defense oriented affinity groups from the LinkedInRTM social media web system. The participants rated their project managers using a 30-item servant leadership scale, and rated the success of their project using a 12-item project success scale. One hundred and fifteen valid responses were analyzed from 231 collected samples from persons who had worked for a project manager on an aerospace and defense project within the past year. The results of the study demonstrated statistically significant levels of positive correlation to project success for all eight servant leadership factors independently evaluated. Using multiple linear regression methods, the servant leadership factors of empowerment and authenticity were determined to be substantial and statistically significant predictors of project success. The study results established the potential application of servant leadership as a valid approach for improving outcomes of projects.

Census U.S. Civil Aircraft Calendar Year 1993

DTIC Science & Technology

1993-12-31

20 - - - - - - - - - Mountain Air Cargo Inc. 24 -. - - - 24 - 24 - - - - - Nations Air Express dba Miami Air Charter ...... - - - - - - 1 - - 1...Ivi ition Associ - ates Inc ......... 12 - - - - 12 - 12 - - - - - - Aviation Sales Incorporated 8 2 - - 2 2 - 2 - 4 - - 4 - - Aviation Serv- ices dba...4.5 Verm ont 791....................................................... ............... 68 9,609 79 9 576 13.3 Northwest Mountain -Total

Playing the Private College Admissions Game.

ERIC Educational Resources Information Center

Moll, Richard

Truths and myths involved with student admission to Ivy League colleges are revealed by a director of admissions whose experience includes admission work at Vassar, Bowdoin, Harvard and Yale. Several basic concepts are offered as fact: most private colleges in America today are not highly selective; many colleges pose as being more selective than…

Effective Partnership between Public Education and Private Industry.

ERIC Educational Resources Information Center

Smith, Sue Griffith; Beatty, David

From the perspectives of both school and industry, this paper outlines the past, present, and future of a partnership between Ivy Tech State College (Columbus, Indiana) and Cummins Engine Company and other local industries formed to provide the southern Indiana area with a highly skilled workforce. First, David Beatty traces on-the-job training at…

Plant Identification.

ERIC Educational Resources Information Center

National Audubon Society, New York, NY.

This set of teaching aids consists of 12 Audubon Nature Bulletins, providing teachers and students with informational reading on plants. The bulletins include these titles: The Parade of Spring Wild Flowers, Wild Flowers of Our Prairies, Seeds and How They Travel, Poison Ivy and Other Poisonous Plants, The Forest Community, Common Trees and Their…

Successful treatment of poison oak dermatitis treated with Grindelia spp. (Gumweed).

PubMed

Canavan, Don; Yarnell, Eric

2005-08-01

Poison oak and related hypersensitivity dermatitides are age-old problems that have historically been treated with herbal medicines before the availability of corticosteroids. Few of these historical therapies have been rigorously investigated. The case presented here provides some insight into the potential efficacy of certain herbs for relieving mild-to-moderate poison ivy dermatitis.

Moving Heaven and Earth: Administrative Search and Selection Processes and the Experience of an African American Woman Senior Administrator

ERIC Educational Resources Information Center

Barnett-Johnson, Kim R.

2009-01-01

The purpose of this case/phenomenological study was to examine a collegiate administrative search and selection process and the experience of an African American woman who was selected to the position of chancellor. A case concerning the search process of a regional campus of Ivy Tech Community College of Indiana was identified and chosen.…

The Shape of Things to Come: A Photo Essay

ERIC Educational Resources Information Center

Connection: The Journal of the New England Board of Higher Education, 2002

2002-01-01

Think of New England higher education and one probably thinks of ivy-covered brick or perhaps 1950s concrete, but the environment of New England's college campuses is far more diverse, more complex, more daring, and more educational than the stereotype. It is changing fast, thanks to profound forces such as consumerization among students,…

The Well-Read College-Bound Student.

ERIC Educational Resources Information Center

Epstein, Connie C.

1984-01-01

Presents results of poll of 13 English departments of Ivy League and Seven Sister colleges and universities undertaken in order to offer high school librarians an up-to-date checklist of basic titles that should be included in their collections. Fifty-three authors cited and a bibliography of 51 recommended titles are included. (EJS)

Sensemaking during the Use of Learning Analytics in the Context of a Large College System

ERIC Educational Resources Information Center

Morse, Robert Kenneth

2017-01-01

This research took place as a cognitive exploration of sensemaking of learning analytics at Ivy Tech Community College of Indiana. For the courses with the largest online enrollment, quality standards in the course design are maintained by creating sections from a course design framework. This means all sections have the same starting content and…

Holistic Support That Promotes Student Learning

ERIC Educational Resources Information Center

Dennis, Sophie Lampard; Osterholt, Dorothy A.

2011-01-01

For decades, the cost of serving college students, from community colleges to Ivy League institutions, has been a barrier that has blocked access for many who want an education. With a recent massification effort aimed at producing more college graduates for the workplace, the enrollment numbers have increased and student debt load has become a…

Argumentative and Trustworthy Scholars: The Construction of Academic Staff at Research-Intensive Universities

ERIC Educational Resources Information Center

McKenna, Sioux; Boughey, Chrissie

2014-01-01

Research-intensive universities, such as the Russell Group in the UK, the Ivy League Colleges in the USA and the Sandstone Universities in Australia, enjoy particular status in the higher education landscape. They are, however, also often associated with social elitism and selectivity, and this has led to critique as higher education systems seek…

main_title.html

Science.gov Websites

Poison Ivy Prairie Insects in Winter Red-tailed Hawk West Nile Virus Woodchuck Prairie Resources Deer and Beaver Bird Nests Buffalo Canada Geese Deer Fungi Grass Insects Lichens Math Patterns in Nature ;, Educational Images Ltd., Elmira, NY, used with permission. Red-tailed hawk: Original artwork: Louis Agassiz

A System Status Monitor for the National Aerospace Plane.

DTIC Science & Technology

1987-12-01

12 4.5 Remediation Function .. 17 V. Results .. .. . .. . . .. . . .. . . . . ... .... . 5.1 Test IA...5.2 Test IlB.... .. .. .. .. .. .............. .G2 . 5.3 Test IC . . . . . . ..... 5.5 Te.st ILE . 71 -N IVI ,. .**,*, 𔃻’ d* *-*-’ . d...8217*?~~** ~ % ~~ *~*%’** ~ %?, P age 5.6 Test 2A .. .. .... .... ... .... .... .... .... .... .... 73 5.7 Test213. .. ... .... .... .... ... .... .... .... ..... 7

Layoffs Introduce a College Town to Uncertainty

ERIC Educational Resources Information Center

Fischer, Karin

2009-01-01

For the first time in decades, the economic headlines are hitting Hanover residents where they live. In February, Dartmouth College, a member of the Ivy League and the region's second-largest employer, announced it was laying off 60 workers, all in nonfaculty positions, and eliminating another 90 jobs through early retirements and attrition, part…

AGRI Grain Power ethanol-for-fuel project feasibility-study report. Volume I. Project conceptual design

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1981-04-01

The AGRI GRAIN POWER (AGP) Project, hereafter referred to as the Project, was formed to evaluate the commercial viability and assess the desireability of implementing a large grain based grass-roots anhydrous ethanol fuel project to be sited near Des Moines, Iowa. This report presents the results of a Project feasibility evaluation. The Project concept is based on involving a very strong managerial, financial and technical joint venture that is extremely expert in all facets of planning and implementing a large ethanol project; on locating the ethanol project at a highly desireable site; on utilizing a proven ethanol process; and onmore » developing a Project that is well suited to market requirements, resource availability and competitive factors. The Project conceptual design is presented in this volume.« less

An Innovative Project in Educational Technology: The Panama-Venezuela Project.

ERIC Educational Resources Information Center

Rojas, Alicia Mabel

1980-01-01

Describes a project which is being implemented in the field of educational technology in Panama and Venezuela. The project emphasizes inservice training of a cadre of professionals who will direct efforts to identify and resolve significant problems in education. (Author/CHC)

SDN Project

DOE Office of Scientific and Technical Information (OSTI.GOV)

Smith, Rhett

The SDN Project completed on time and on budget and successfully accomplished 100% of the scope of work outlined in the original Statement of Project Objective (SOPO). The SDN Project formed an alliance between Ameren Corporation, University of Illinois Urbana- Champaign (UIUC), Pacific Northwest National Laboratories (PNNL), and Schweitzer Engineering Laboratories, Inc. (SEL). The objective of the SDN Project is to address Topic Area of Interest 2: Sustain critical energy delivery functions while responding to a cyber-intrusion under Funding Opportunity Announcement DE-FOA-0000797. The goal of the project is to design and commercially release technology that provides a method to sustainmore » critical energy delivery functions during a cyber intrusion and to do this control system operators need the ability to quickly identify and isolate the affected network areas, and re-route critical information and control flows around. The objective of the SDN Project is to develop a Flow Controller that monitors, configures, and maintains the safe, reliable network traffic flows of all the local area networks (LANs) on a control system in the Energy sector. The SDN team identified the core attributes of a control system and produced an SDN flow controller that has the same core attributes enabling networks to be designed, configured and deployed that maximize the whitelisted, deny-bydefault and purpose built networks. This project researched, developed and commercially released technology that: Enables all field networks be to configured and monitored as if they are a single asset to be protected; Enables greatly improved and even precalculated response actions to reliability and cyber events; Supports pre-configured localized response actions tailored to provide resilience against failures and centralized response to cyber-attacks that improve network reliability and availability; Architecturally enables the right subject matter experts, who are usually the information

Evaluation of nanoformulated therapeutics in an ex-vivo bovine corneal irritation model.

PubMed

Bhasker, Sriramoju; Kislay, Roy; Rupinder, Kanwar K; Jagat, Kanwar R

2015-08-01

To determine the internalization and protective effects of potential ophthalmic formulations and nanoformulated natural proteins in ex-vivo bovine corneal alkali burn model. The bovine cornea obtained were subjected to the 0.5N NaOH insult that induced alkali burn and inflammation as observed in the in vivo situation. The toxic effects of the nanoformulation were evaluated in the normal and insult induced cornea using histological analysis. Internalization studies were carried out using in vivo imaging and analysis (IVIS, PerkinElmer, USA). The nanoformulations employed in this study showed no obvious changes in the integrity of the cornea. Further, improvements in the light transmittance and reduced inflammation were observed. The IVIS showed a dose dependant increase in the uptake of the nanoformulations with time. The nanoformulated bovine lactoferrin and SurR9-C84A (SR9) proteins evaluated in the ex vivo bovine corneal irritation model is the first of its kind, and we report here the non-toxic and therapeutic potential of these formulations for topical applications. Copyright © 2015 Elsevier Ltd. All rights reserved.

Identification of Actinobacillus pleuropneumoniae Genes Preferentially Expressed During Infection Using In Vivo-Induced Antigen Technology (IVIAT).

PubMed

Zhang, Fei; Zhang, Yangyi; Wen, Xintian; Huang, Xiaobo; Wen, Yiping; Wu, Rui; Yan, Qigui; Huang, Yong; Ma, Xiaoping; Zhao, Qin; Cao, Sanjie

2015-10-01

Porcine pleuropneumonia is an infectious disease caused by Actinobacillus pleuropneumoniae. The identification of A. pleuropneumoniae genes, specially expressed in vivo, is a useful tool to reveal the mechanism of infection. IVIAT was used in this work to identify antigens expressed in vivo during A. pleuropneumoniae infection, using sera from individuals with chronic porcine pleuropneumonia. Sequencing of DNA inserts from positive clones showed 11 open reading frames with high homology to A. pleuropneumoniae genes. Based on sequence analysis, proteins encoded by these genes were involved in metabolism, replication, transcription regulation, and signal transduction. Moreover, three function-unknown proteins were also indentified in this work. Expression analysis using quantitative real-time PCR showed that most of the genes tested were up-regulated in vivo relative to their expression levels in vitro. IVI (in vivoinduced) genes that were amplified by PCR in different A. pleuropneumoniae strains showed that these genes could be detected in almost all of the strains. It is demonstrated that the identified IVI antigen may have important roles in the infection of A. pleuropneumoniae.

Project Artemis

NASA Technical Reports Server (NTRS)

Birchenough, Shawn; Kato, Denise; Kennedy, Fred; Akin, David

1990-01-01

The goals of Project Artemis are designed to meet the challege of President Bush to return to the Moon, this time to stay. The first goal of the project is to establish a permanent manned base on the Moon for the purposes of scientific research and technological development. The knowledge gained from the establishment and operations of the lunar base will then be used to achieve the second goal of Project Artemis, the establishment of a manned base on the Martian surface. Throughout both phases of the program, crew safety will be the number one priority. There are four main issues that have governed the entire program: crew safety and mission success, commonality, growth potential, and costing and scheduling. These issues are discussed in more detail.

Research Projects for Undergraduates

NASA Astrophysics Data System (ADS)

Troncalli, Andra

2010-03-01

Physics majors, by enrolling in our research experience in physics course, have the opportunity to work in small groups on independent research projects. Over the last few years, I have directed a few of these research projects; some were closely related to my own research in the field of high temperature superconductivity, and students participated in growing and characterizing samples. Other projects involved nanotechnology, Hall probes, and programming in LabVIEW. For some students, this was their very first research project, while others had more experience. I will talk about the projects and about the particular type of challenges and benefits this type of course brings to both students and instructors.

The Role of the Project Management Office on Information Technology Project Success

ERIC Educational Resources Information Center

Stewart, Jacob S.

2010-01-01

The rate of failed and challenged Information Technology (IT) projects is too high according to the CHAOS Studies by the Standish Group and the literature on project management (Standish Group, 2008). The CHAOS Studies define project success as meeting the triple constraints of scope, time, and cost. Assessing critical success factors is another…

The Interactions among Information Technology Organizational Learning, Project Learning, and Project Success

ERIC Educational Resources Information Center

McKay, Donald S., II

2012-01-01

Knowledge gained from completed information technology (IT) projects was not often shared with emerging project teams. Learning lessons from other project teams was not pursued because people lack time, do not see value in learning, fear a potentially painful process, and had concerns that sharing knowledge will hurt their career. Leaders could…

Draft project management update to the Iowa DOT Project Development Manual : final report.

DOT National Transportation Integrated Search

2016-08-01

This work supported drafting project management guidance for the Iowa Department of Transportation (DOT). The goal is to : incorporate a greater focus on project management in their project development process. : A technical advisory committee (TAC) ...

I-15 North Project

DOT National Transportation Integrated Search

2013-11-05

Goals of this project were as follows: (1) Conduct a comprehensive evaluation study on Nevada's I-15 North Design Build Project; (2) Analyze project implementation with respect to construction zone rules by which the contractor had to abide; (3) Anal...

Project management process.

DOT National Transportation Integrated Search

2007-03-01

This course provides INDOT staff with foundational knowledge and skills in project management principles and methodologies. INDOTs project management processes provide the tools for interdisciplinary teams to efficiently and effectively deliver pr...

"Cheesy Pizza": The Pizza Project

ERIC Educational Resources Information Center

Gallick, Barbara; Lee, Lisa

2009-01-01

A class of 3- to 5-year-old children in a midwestern child care center chose to study pizza restaurants as a group project. This article discusses how the project evolved, describes the three phases of the project, and provides the teachers' reflections on the project. Photos taken during the project and children's sketches are included. (Contains…